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Sample records for modeling system mims

  1. MIMS - MEDICAL INFORMATION MANAGEMENT SYSTEM

    Science.gov (United States)

    Frankowski, J. W.

    1994-01-01

    MIMS, Medical Information Management System is an interactive, general purpose information storage and retrieval system. It was first designed to be used in medical data management, and can be used to handle all aspects of data related to patient care. Other areas of application for MIMS include: managing occupational safety data in the public and private sectors; handling judicial information where speed and accuracy are high priorities; systemizing purchasing and procurement systems; and analyzing organizational cost structures. Because of its free format design, MIMS can offer immediate assistance where manipulation of large data bases is required. File structures, data categories, field lengths and formats, including alphabetic and/or numeric, are all user defined. The user can quickly and efficiently extract, display, and analyze the data. Three means of extracting data are provided: certain short items of information, such as social security numbers, can be used to uniquely identify each record for quick access; records can be selected which match conditions defined by the user; and specific categories of data can be selected. Data may be displayed and analyzed in several ways which include: generating tabular information assembled from comparison of all the records on the system; generating statistical information on numeric data such as means, standard deviations and standard errors; and displaying formatted listings of output data. The MIMS program is written in Microsoft FORTRAN-77. It was designed to operate on IBM Personal Computers and compatibles running under PC or MS DOS 2.00 or higher. MIMS was developed in 1987.

  2. MIMS - MEDICAL INFORMATION MANAGEMENT SYSTEM

    Science.gov (United States)

    Frankowski, J. W.

    1994-01-01

    MIMS, Medical Information Management System is an interactive, general purpose information storage and retrieval system. It was first designed to be used in medical data management, and can be used to handle all aspects of data related to patient care. Other areas of application for MIMS include: managing occupational safety data in the public and private sectors; handling judicial information where speed and accuracy are high priorities; systemizing purchasing and procurement systems; and analyzing organizational cost structures. Because of its free format design, MIMS can offer immediate assistance where manipulation of large data bases is required. File structures, data categories, field lengths and formats, including alphabetic and/or numeric, are all user defined. The user can quickly and efficiently extract, display, and analyze the data. Three means of extracting data are provided: certain short items of information, such as social security numbers, can be used to uniquely identify each record for quick access; records can be selected which match conditions defined by the user; and specific categories of data can be selected. Data may be displayed and analyzed in several ways which include: generating tabular information assembled from comparison of all the records on the system; generating statistical information on numeric data such as means, standard deviations and standard errors; and displaying formatted listings of output data. The MIMS program is written in Microsoft FORTRAN-77. It was designed to operate on IBM Personal Computers and compatibles running under PC or MS DOS 2.00 or higher. MIMS was developed in 1987.

  3. Modular Integrated Monitoring System (MIMS) field test installations

    Energy Technology Data Exchange (ETDEWEB)

    Martinez, R.L.; Waymire, D.R. [Sandia National Labs., Albuquerque, NM (United States); Fuess, D.A. [Lawrence Livermore National Lab., CA (United States)] [and others

    1995-07-01

    The MIMS program is funded by the Department of Energy under the Office of Nonproliferation and National Security. The program objective is to develop cost effective, modular, multi-sensor monitoring systems. Both in-plant and ground based sensors are envisioned. It is also desirable to develop sensors/systems that can be fielded/deployed in a rapid fashion. A MIMS architecture was selected to allow modular integration of sensors and systems and is based on LonWorks technology, commercially developed by Echelon Corporation. The first MIMS fieldable hardware was demonstrated at Lawrence Livermore National Laboratory. The field test, known within the DOE as the Item Tracking and Transparency (IT&I) demonstration, involved the collaboration and cooperation of five DOE laboratories (Sandia (SNL), Lawrence Livermore (LLNL), Pacific Northwest (PNL), Los Alamos (LANL), and Oak Ridge (ORNL)). The IT&T demonstration involved the monitoring of special nuclear material as it was transported around the facility utilizing sensors from the participating labs. The scenario was programmed to ignore normal activity in the facility until entry into the room where the material was stored. A second demonstration, which involved three separate scenarios, was conducted at Idaho National Engineering Laboratory (INEL). The participants included representatives from SNL, LLNL, PNL, and INEL. DOE has selected INEL as the long term testbed for MIMS developed sensors, systems, and scenarios. This paper will describe the installation, intended purpose, and results of the field demonstrations at LLNL and INEL under the MIMS program.

  4. MIMS for TRIM

    Science.gov (United States)

    MIMS supports complex computational studies that use multiple interrelated models / programs, such as the modules within TRIM. MIMS is used by TRIM to run various models in sequence, while sharing input and output files.

  5. Mainz Isoprene Mechanism 2 (MIM2: an isoprene oxidation mechanism for regional and global atmospheric modelling

    Directory of Open Access Journals (Sweden)

    D. Taraborrelli

    2009-04-01

    Full Text Available We present an oxidation mechanism of intermediate size for isoprene (2-methyl-1,3-butadiene suitable for simulations in regional and global atmospheric chemistry models, which we call MIM2. It is a reduction of the corresponding detailed mechanism in the Master Chemical Mechanism (MCM v3.1 and intended as the second version of the well-established Mainz Isoprene Mechanism (MIM. Our aim is to improve the representation of tropospheric chemistry in regional and global models under all NOx regimes. We evaluate MIM2 and re-evaluate MIM through comparisons with MCM v3.1. We find that MIM and MIM2 compute similar O3, OH and isoprene mixing ratios. Unlike MIM, MIM2 produces small relative biases for NOx and organic nitrogen-containing species due to a good representation of the alkyl and peroxy acyl nitrates (RONO2 and RC(OOONO2. Moreover, MIM2 computes only small relative biases with respect to hydrogen peroxide (H2O2, methyl peroxide (CH3OOH, methanol (CH3OH, formaldehyde (HCHO, peroxy acetyl nitrate (PAN, and formic and acetic acids (HCOOH and CH3C(OOH, being always below ≈6% in all NOx scenarios studied. Most of the isoprene oxidation products are represented explicitly, including methyl vinyl ketone (MVK, methacrolein (MACR, hydroxyacetone and methyl glyoxal. MIM2 is mass-conserving with respect to carbon, including CO2 as well. Therefore, it is suitable for studies assessing carbon monoxide (CO from biogenic sources, as well as for studies focused on the carbon cycle. Compared to MIM, MIM2 considers new species like acetaldehyde (CH3CHO, propene (CH2=CHCH3 and glyoxal (CHOCHO with global chemical production rates for the year 2005 of 7.3, 9.5 and 33.8 Tg/yr, respectively. Our new mechanism is expected to substantially improve the results of atmospheric chemistry models by

  6. Mainz Isoprene Mechanism 2 (MIM2: an isoprene oxidation mechanism for regional and global atmospheric modelling

    Directory of Open Access Journals (Sweden)

    D. Taraborrelli

    2008-07-01

    Full Text Available We present an oxidation mechanism of intermediate size for isoprene (2-methyl-1,3-butadiene suitable for simulations in regional and global atmospheric chemistry models, which we call MIM2. It is a reduction of the corresponding detailed mechanism in the Master Chemical Mechanism (MCM v3.1 and intended as the second version of the well-established Mainz Isoprene Mechanism (MIM. Our aim is to improve the representation of tropospheric chemistry in regional and global models under all NOx regimes. We evaluate MIM2 and re-evaluate MIM through comparisons with MCM v3.1. We find that MIM and MIM2 compute similar O3, OH and isoprene mixing ratios. Unlike MIM, MIM2 produces small relative biases for NOx and organic nitrogen-containing species due to a good representation of the alkyl and peroxy acyl nitrates (RONO2 and RC(OOONO2. Moreover, MIM2 computes only small relative biases with respect to hydrogen peroxide (H2O2, methyl peroxide (CH3OOH, methanol (CH3OH, formaldehyde (HCHO, peroxy acetyl nitrate (PAN, and formic and acetic acids (HCOOH and CH3C(OOH, being always below ≈6% in all NOx scenarios studied. Most of the isoprene oxidation products are represented explicitly, including methyl vinyl ketone (MVK, methacrolein (MACR, hydroxyacetone and methyl glyoxal. MIM2 is mass-conserving with respect to carbon, including CO2 as well. Therefore, it is suitable for studies assessing carbon monoxide (CO from biogenic sources, as well as for studies focused on the carbon cycle. Compared to MIM, MIM2 considers new species like acetaldehyde (CH3CHO, propene (CH2=CHCH3 and glyoxal (CHOCHO with global chemical production rates for the year 2005 of 7.3, 9.5 and 33.8 Tg/yr, respectively. Our new mechanism is expected to substantially improve the results of atmospheric chemistry models by more

  7. Interaction of pepsin-[C16mim]Br system: interfacial dilational rheology and conformational studies.

    Science.gov (United States)

    Huang, Tian; Cao, Chong; Liu, Zi-lin; Li, Yang; Du, Feng-pei

    2014-09-21

    The interfacial rheological property is closely related to the stabilities of foams and emulsions, yet there have been limited studies on the interaction between proteins with ionic liquid-type imidazolium surfactants at the decane-water interface as well as in the bulk. Herein, we investigated the interfacial and bulk properties of pepsin (PEP) and an ionic liquid (IL), 1-hexadecyl-3-methylimidazolium bromide, [C(16)mim]Br. The interfacial pressure and dilational rheology studies were performed to describe the formation of [C(16)mim]Br-pepsin complexes. The influence of the oscillating frequency and the bulk concentration of [C(16)mim]Br on the dilational properties were explored. The conformational changes were studied by monitoring the fluorescence and far UV-CD spectra. The results reveal that the globular structure of pepsin is one of the decisive factors controlling the nature of the interfacial film. The monotonous increase in the dilational elastic modulus of pepsin-[C(16)mim]Br solutions with the surface age indicates that no loops and tails had formed. Interestingly, with an increase in the concentration of [C(16)mim]Br, the εd-c curve first passes through a plateau value due to steric hindrance and the electrostatic barrier of already absorbed tenacious pepsin-[C(16)mim]Br complexes. With the further addition of [C(16)mim]Br, the remarkable decrease in dilational elastic modulus indicates that the compact structure is destroyed gradually. The results of the fluorescence spectra and far UV-CD spectra confirm that [C(16)mim]Br did not produce perceptible changes in pepsin at the concentrations studied in the dilational experiment. Possible schematic programs of the pepsin-[C(16)mim]Br interaction model at the interface and in bulk phase are proposed.

  8. Determination and modelling of osmotic coefficients and vapour pressures of binary systems 1- and 2-propanol with C{sub n}MimNTf{sub 2} ionic liquids (n = 2, 3, and 4) at T = 323.15 K

    Energy Technology Data Exchange (ETDEWEB)

    Calvar, Noelia [LSRE - Laboratory of Separation and Reaction Engineering, Associate Laboratory, LSRE/LCM, Department of Chemical Engineering, Faculty of Engineering, Rua Dr. Roberto Frias s/n, Porto 4200-465 (Portugal); Gomez, Elena; Dominguez, Angeles [Advanced Separation Processes Group, Department of Chemical Engineering, University of Vigo, 36310 Vigo (Spain); Macedo, Eugenia A., E-mail: eamacedo@fe.up.pt [LSRE - Laboratory of Separation and Reaction Engineering, Associate Laboratory, LSRE/LCM, Department of Chemical Engineering, Faculty of Engineering, Rua Dr. Roberto Frias s/n, Porto 4200-465 (Portugal)

    2011-08-15

    Highlights: > Osmotic coefficients of 1- and 2-propanol with C{sub n}MimNTf{sub 2} (n = 2, 3, and 4) are determined. > Experimental data were correlated with extended Pitzer model of Archer and MNRTL. > Mean molal activity coefficients and excess Gibbs free energies were calculated. > Effect of the anion is studied comparing these results with literature. - Abstract: The osmotic and activity coefficients and vapour pressures of binary mixtures containing 1-propanol, or 2-propanol and imidazolium-based ionic liquids with bis(trifluoromethylsulfonyl)imide as anion (1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide, C{sub 2}MimNTf{sub 2}, 1-methyl-3-propylimidazolium bis(trifluoromethylsulfonyl)imide, C{sub 3}MimNTf{sub 2}, and 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide, C{sub 4}MimNTf{sub 2}) were determined at T = 323.15 K using the vapour pressure osmometry technique. The experimental osmotic coefficients were correlated using the extended Pitzer model modified by Archer and the MNRTL model, obtaining standard deviations lower than 0.033 and 0.064, respectively. The mean molal activity coefficients and the excess Gibbs free energy for the mixtures studied were calculated from the parameters of the extended Pitzer model modified by Archer. Besides the effect of the alkyl-chain of the cation, the effect of the anion can be assessed comparing the experimental results with those previously obtained for imidazolium ionic liquids with sulphate anions.

  9. Medical Information Management System (MIMS): A generalized interactive information system

    Science.gov (United States)

    Alterescu, S.; Friedman, C. A.; Hipkins, K. R.

    1975-01-01

    An interactive information system is described. It is a general purpose, free format system which offers immediate assistance where manipulation of large data bases is required. The medical area is a prime area of application. Examples of the system's operation, commentary on the examples, and a complete listing of the system program are included.

  10. Medical Information Management System (MIMS): A Generalized Interactive Information System.

    Science.gov (United States)

    Alterescu,Sidney; And Others

    This report describes an interactive information system. It is a general purpose, free format system which can offer immediate assistance where manipulation of large data bases is required. The medical area is a prime area of application. The report is designed to serve as a manual for potential users--nontechnical personnel who will use the…

  11. Metastable Innershell Molecular State (MIMS) IV: Heteronucleus K-shell MIMS with H+ and He+

    OpenAIRE

    Bae, Young K.

    2014-01-01

    The model of MIMS (Metastable Innershell Molecular State) has been applied to interpreting the Kα X-ray satellite data of target atoms in H+ and He+ ion impact on Al, Ca and Ti targets. The binding energies of the heteronucleus H-K-MIMS (K-shell MIMS formed with H and a target atom) and He-K-MIMS have been obtained. The binding energy trend of the H-K-MIMS shows a Z2 dependency similar to that of the homonucleus K-MIMS, while that of the He-K-MIMS shows a transitional behavior from the former...

  12. Image fusion using MIM software via picture archiving and communication system

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The preliminary studies of the multimodality image registration andfusion were performed using an image fusion software and a picture archiving andcommunication system (PACS) to explore the methodology. Original image voluminaldata were acquired with a CT scanner, MR and dual-head coincidence SPECT, respec-tively. The data sets from all imaging devices were queried, retrieved, transferred andaccessed via DICOM PACS. The image fusion was performed at thc SPECT ICONwork-station, where the MIM (Medical Image Merge) fusion software was installed.The images were created by reslicing original volume on the fly. The image volumeswere aligned by translation and rotation of these view ports with respect to the origi-nal volume orientation. The transparency factor and contrast were adjusted in orderthat both volumes can be visualized in the merged images. The image volume data ofCT, MR and nuclear medicine were transferred, accessed and loaded via PACS suc-cessfully. The perfect fused images of chest CT/18F-FDG and brain MR/SPECT wereobtained. These results showed that image fusion technique using PACS was feasibleand practical. Further experimentation and larger validation studies were needed toexplore the full potential of the clinical use.

  13. Implementation of a Marauding Insect Module (MIM, version 1.0) in the Integrated BIosphere Simulator (IBIS, version 2.6b4) dynamic vegetation-land surface model

    Science.gov (United States)

    Landry, Jean-Sébastien; Price, David T.; Ramankutty, Navin; Parrott, Lael; Damon Matthews, H.

    2016-04-01

    Insects defoliate and kill plants in many ecosystems worldwide. The consequences of these natural processes on terrestrial ecology and nutrient cycling are well established, and their potential climatic effects resulting from modified land-atmosphere exchanges of carbon, energy, and water are increasingly being recognized. We developed a Marauding Insect Module (MIM) to quantify, in the Integrated BIosphere Simulator (IBIS), the consequences of insect activity on biogeochemical and biogeophysical fluxes, also accounting for the effects of altered vegetation dynamics. MIM can simulate damage from three different insect functional types: (1) defoliators on broadleaf deciduous trees, (2) defoliators on needleleaf evergreen trees, and (3) bark beetles on needleleaf evergreen trees, with the resulting impacts being estimated by IBIS based on the new, insect-modified state of the vegetation. MIM further accounts for the physical presence and gradual fall of insect-killed dead standing trees. The design of MIM should facilitate the addition of other insect types besides the ones already included and could guide the development of similar modules for other process-based vegetation models. After describing IBIS-MIM, we illustrate the usefulness of the model by presenting results spanning daily to centennial timescales for vegetation dynamics and cycling of carbon, energy, and water in a simplified setting and for bark beetles only. More precisely, we simulated 100 % mortality events from the mountain pine beetle for three locations in western Canada. We then show that these simulated impacts agree with many previous studies based on field measurements, satellite data, or modelling. MIM and similar tools should therefore be of great value in assessing the wide array of impacts resulting from insect-induced plant damage in the Earth system.

  14. Mindfulness Integrative Model (MIM: cultivating positive states of mind towards oneself and the others through mindfulness and self-compassion

    Directory of Open Access Journals (Sweden)

    Raquel Rodríguez-Carvajal

    Full Text Available There are more and more studies showing the effectiveness of Mindfulness-based interventions (MBI in well-being. However, there are few studies that explore the mechanisms underlying this effect. The aim of this study is to present and validate the Integrative Model of Mindfulness (MIM. MIM main hypothesis is that mindfulness practice leads to an increment in mindfulness trait, which leads to an increase of selfcompassion, and these in turn, lead to increase positive mental states towards others and oneself. A MBI intensive three-week with non-randomized controlled group was designed. Participants (N = 87 were differentiated by meditation experience as well. The results show large effect sizes regarding the effect of MBI on mindfulness trait, self-compassion and positive mental states to oneself and to others. The data support the MIM, indicating that the practice of mindfulness meditation leads in a sequentially way to the cultivation of mindfulness and self-compassion, which subsequently appears to lead to the development of positive mental states towards others and oneself.

  15. Metastable Innershell Molecular State (MIMS IV: Heteronucleus K-shell MIMS with H+ and He+

    Directory of Open Access Journals (Sweden)

    Young K. Bae

    2014-01-01

    Full Text Available The model of MIMS (Metastable Innershell Molecular State has been applied to interpreting the Kα X-ray satellite data of target atoms in H+ and He+ ion impact on Al, Ca and Ti targets. The binding energies of the heteronucleus H-K-MIMS (K-shell MIMS formed with H and a target atom and He-K-MIMS have been obtained. The binding energy trend of the H-K-MIMS shows a Z2 dependency similar to that of the homonucleus K-MIMS, while that of the He-K-MIMS shows a transitional behavior from the former to the latter. These behaviors were interpreted with the Z-expansion theory of heteronucleus molecules.

  16. Metastable Innershell Molecular State (MIMS) IV: Heteronucleus K-shell MIMS with H+ and He+

    Science.gov (United States)

    Bae, Young K.

    The model of MIMS (Metastable Innershell Molecular State) has been applied to interpreting the Kα X-ray satellite data of target atoms in H+ and He+ ion impact on Al, Ca and Ti targets. The binding energies of the heteronucleus H-K-MIMS (K-shell MIMS formed with H and a target atom) and He-K-MIMS have been obtained. The binding energy trend of the H-K-MIMS shows a Z2 dependency similar to that of the homonucleus K-MIMS, while that of the He-K-MIMS shows a transitional behavior from the former to the latter. These behaviors were interpreted with the Z-expansion theory of heteronucleus molecules.

  17. GENERATING SOPHISTICATED SPATIAL SURROGATES USING THE MIMS SPATIAL ALLOCATOR

    Science.gov (United States)

    The Multimedia Integrated Modeling System (MIMS) Spatial Allocator is open-source software for generating spatial surrogates for emissions modeling, changing the map projection of Shapefiles, and performing other types of spatial allocation that does not require the use of a comm...

  18. Measurement of spatial and temporal variation in volatile hazardous air pollutants in Tacoma, Washington, using a mobile membrane introduction mass spectrometry (MIMS) system.

    Science.gov (United States)

    Davey, Nicholas G; Fitzpatrick, Cole T E; Etzkorn, Jacob M; Martinsen, Morten; Crampton, Robert S; Onstad, Gretchen D; Larson, Timothy V; Yost, Michael G; Krogh, Erik T; Gilroy, Michael; Himes, Kathy H; Saganić, Erik T; Simpson, Christopher D; Gill, Christopher G

    2014-09-19

    The objective of this study was to use membrane introduction mass spectrometry (MIMS), implemented on a mobile platform, in order to provide real-time, fine-scale, temporally and spatially resolved measurements of several hazardous air pollutants. This work is important because there is now substantial evidence that fine-scale spatial and temporal variations of air pollutant concentrations are important determinants of exposure to air pollution and adverse health outcomes. The study took place in Tacoma, WA during periods of impaired air quality in the winter and summer of 2008 and 2009. Levels of fine particles were higher in winter compared to summer, and were spatially uniform across the study area. Concentrations of vapor phase pollutants measured by membrane introduction mass spectrometry (MIMS), notably benzene and toluene, had relatively uniform spatial distributions at night, but exhibited substantial spatial variation during the day-daytime levels were up to 3-fold higher at traffic-impacted locations compared to a reference site. Although no direct side-by-side comparison was made between the MIMS system and traditional fixed site monitors, the MIMS system typically reported higher concentrations of specific VOCs, particularly benzene, ethylbenzene and naphthalene, compared to annual average concentrations obtained from SUMA canisters and gas chromatographic analysis at the fixed sites.

  19. Mindfulness Integrative Model (MIM): Cultivating positive states of mind towards oneself and the others through mindfulness and self-compassion

    National Research Council Canada - National Science Library

    Raquel Rodríguez-Carvajal; Carlos García-Rubio; David Paniagua; Gustavo García-Diex

    2016-01-01

    ...). MIM main hypothesis is that mindfulness practice leads to an increment in mindfulness trait, which leads to an increase of self-compassion, and these in turn, lead to increase positive mental states...

  20. Characterization of Stainless Steel 316L Feedstock for Metal Injection Molding (MIM) Using Waste Polystyrene and Palm Kernel Oil Binder System

    Science.gov (United States)

    Asmawi, R.; Ibrahim, M. H. I.; Amin, A. M.; Mustafa, N.

    2016-11-01

    This paper presents the homogeneity characterisation of MIM feedstock consisting Stainless steel alloy (316 L) powder mix with binder 60wt% of waste polystyrene and 40wt% palm kernel oil. It is one of a critical step that must be conducted in MIM process in order to have a feedstock that is homogeneous and moldable. Water atomised Stainless Steel powder was mixed with the newly developed binder system in a Brabender Plastograph EC rotary mixer. Several tests were performed to assess the homogeneity of the feedstock that was produced at 60 vol % powder loading . The 60 vol.% was chosen because the Critical Powder Volume Concentration (CPVC) of the Powder was found to be 64.8 vol.%. The tests conducted were feedstock density, binder burn-out, rheology and SEM morphology observation. Rheological results exhibited pseudoplastic or shear thinning flow behavior, where its viscosity decreased with increasing shear rate. The feedstock viscosity also decreased with increasing temperature and was found to be suitable for molding. From all the tests conducted, it was found that the feedstock shows good homogeneity and suitable for subsequent processes in MIM.

  1. Monolithic interconnected modules (MIMs) for thermophotovoltaic energy conversion

    Science.gov (United States)

    Wilt, David; Wehrer, Rebecca; Palmisiano, Marc; Wanlass, Mark; Murray, Christopher

    2003-05-01

    Monolithic interconnected modules (MIMs) are under development for thermophotovoltaic (TPV) energy conversion applications. MIM devices are typified by series-interconnected photovoltaic cells on a common, semi-insulating substrate and generally include rear-surface infrared (IR) reflectors. The MIM architecture is being implemented in InGaAsSb materials without semi-insulating substrates through the development of alternative isolation methodologies. Motivations for developing the MIM structure include: reduced resistive losses, higher output power density than for systems utilizing front surface spectral control, improved thermal coupling and ultimately higher system efficiency. Numerous design and material changes have been investigated since the introduction of the MIM concept in 1994. These developments as well as the current design strategies are addressed.

  2. THE EPA MULTIMEDIA INTEGRATED MODELING SYSTEM SOFTWARE SUITE

    Science.gov (United States)

    The U.S. EPA is developing a Multimedia Integrated Modeling System (MIMS) framework that will provide a software infrastructure or environment to support constructing, composing, executing, and evaluating complex modeling studies. The framework will include (1) common software ...

  3. Metastable Innershell Molecular State (MIMS)

    CERN Document Server

    Bae, Young K

    2008-01-01

    We propose that the existence of Metastable Innershell Molecular State (MIMS) was experimentally discovered by Bae et al. in hypervelocity (v>100km/s) impact of nanoparticles. The decay of MIMS resulted in the observed intense soft x-rays in the range of 75 - 100 eV in agreement with Winterberg's recent prediction.

  4. Metastable innershell molecular state (MIMS)

    Science.gov (United States)

    Bae, Young K.

    2008-07-01

    We propose that the existence of Metastable innershell molecular state (MIMS) was experimentally discovered by Bae et al. in hypervelocity ( v>100 km/s) impact of nanoparticles. The decay of MIMS resulted in the observed intense soft x-rays in the range of 75-100 eV in agreement with Winterberg's recent prediction.

  5. Radiation effects on hydrophobic ionic liquid [C4mim][NTf2] during extraction of strontium ions.

    Science.gov (United States)

    Yuan, Liyong; Peng, Jing; Xu, Ling; Zhai, Maolin; Li, Jiuqiang; Wei, Genshuan

    2009-07-02

    The applications of room-temperature ionic liquids (RTILs) in separation of high level radioactive nuclides demand a comprehensive knowledge of the stability and metal ion extraction of RTILs under radiation. Herein, we assessed the influence of gamma-irradiation on the [C(4)mim][NTf(2)]-based extraction system, where [C(4)mim](+) is 1-butyl-3-methylimidazolium and [NTf(2)](-) is bis(trifluoromethylsulfonyl)imide, by solvent extraction of Sr(2+) using irradiated [C(4)mim][NTf(2)] in combination with dicyclohexyl-18-crown-6 (DCH18C6). It was found that the degree of extraction for Sr(2+) from water to irradiated [C(4)mim][NTf(2)] decreased compared with that to unirradiated [C(4)mim][NTf(2)], and the decrement enhanced obviously with increasing dose. NMR spectroscopic probe analysis revealed the formation of acids during irradiation of [C(4)mim][NTf(2)]. The decrease of Sr(2+) partitioning in irradiated [C(4)mim][NTf(2)] is attributed to the competition between H(+) with Sr(2+) to interact with DCH18C6. Accordingly, washing irradiated [C(4)mim][NTf(2)] with water gives a simple way of ionic liquid recycling. Furthermore, the degree of extraction for Sr(2+) from 3 mol.L(-1) nitric acid solution to [C(4)mim][NTf(2)] is independent of the irradiation of [C(4)mim][NTf(2)] since the amount of the radiation-generated H(+) is negligible in such a high acidic solution.

  6. Thermodynamic study of binary mixture of x{sub 1}[C{sub 6}mim][BF{sub 4}] + x{sub 2}1-propanol: Measurements and molecular modeling

    Energy Technology Data Exchange (ETDEWEB)

    Kermanpour, F., E-mail: kermanpour@basu.ac.ir [Faculty of Chemistry, Bu-Ali Sina University, Hamadan 65178-38695 (Iran, Islamic Republic of); Sharifi, T. [Faculty of Chemistry, Bu-Ali Sina University, Hamadan 65178-38695 (Iran, Islamic Republic of)

    2012-01-10

    Highlights: Black-Right-Pointing-Pointer Densities and viscosities for binary mixture of {l_brace}x{sub 1}[C{sub 6}mim][BF{sub 4}] + x{sub 2}1-propanol{r_brace} were measured at different temperatures. Black-Right-Pointing-Pointer The excess molar functions were calculated from the obtained experimental data. Black-Right-Pointing-Pointer These data were correlated with the Redlich-Kister equation and PFP model to obtain the coefficients and standard deviations. - Abstract: Densities, {rho}, and viscosities, {eta}, of pure 1-hexyl-3-methylimidazoliumtetrafluoro borate ([C{sub 6}mim][BF{sub 4}]) and 1-propanol, and their binary mixture {l_brace}x{sub 1}[C{sub 6}mim][BF{sub 4}] + x{sub 2}1-propanol{r_brace} were measured at atmospheric pressure and in the temperature range of 293.15-333.15 K. The excess molar volumes, V{sub m}{sup E}, thermal expansion coefficients, {alpha}, and their excess values, {alpha}{sup E}, isothermal coefficient of excess molar enthalpy, ({partial_derivative}H{sub m}{sup E}/{partial_derivative}p){sub T,x} and excess viscosities, {eta}{sup E}, were calculated from the experimental values of densities and viscosities. The excess molar volumes of the binary mixture are negative over the entire mole fraction range and increase with increasing temperature. Excess viscosities are negative over the entire mole fraction range of the mixture and decrease with increasing temperature. The obtained excess molar volumes and excess viscosities were correlated with the Redlich-Kister equation. The experimental results have also been used to examine the applicability of Prigogine-Flory-Patterson (PFP) theory in predicting the excess molar volume of the binary mixture. It is indicated that agreement between excess molar volumes calculated via PFP theory and the experimental results is good in all temperatures.

  7. Biocompatibility of MIM 316L stainless steel

    Institute of Scientific and Technical Information of China (English)

    ZHU Shai-hong; WANG Guo-hui; ZHAO Yan-zhong; LI Yi-ming; ZHOU Ke-chao; HUANG Bai-yun

    2005-01-01

    To evaluate the bioeompatibility of MIM 316L stainless steel, the percentage of S-period cells were detected by flow cytometry after L929 incubated with extraction of MIM 316L stainless steel, using titanium implant materials of clinical application as the contrast. Both materials were implanted in animal and the histopathological evaluations were carried out. The statistical analyses show that there are no significant differences between two groups (P>0.05), which demonstrates that MIM 316L stainless steel has a good biocompatibility.

  8. Metastable Innershell Molecular State (MIMS II: K-shell X-ray satellites in heavy ion impact on solids

    Directory of Open Access Journals (Sweden)

    Young K. Bae

    2014-01-01

    Full Text Available Metastable Innershell Molecular State (MIMS, an innershell-bound ultra-high-energy molecule, was previously proposed to explain a ∼40% efficiency of soft-X-ray generation in ∼0.05 keV/amu nanoparticle impact on solids. Here, the MIMS model has been extended and applied to interpreting the experimental K-shell X-ray satellite spectra for more than 40 years in keV-MeV/amu heavy-ion impact on solids. The binding energies of the K-shell MIMS of elements from Al to Ti were determined to be 80–200 eV. The successful extension of the model to the K-shell MIMS confirms that all elements in the periodic table and their combinations are subjected to the MIMS formation.

  9. Metastable Innershell Molecular State (MIMS) II: K-shell X-ray satellites in heavy ion impact on solids

    Science.gov (United States)

    Bae, Young K.

    Metastable Innershell Molecular State (MIMS), an innershell-bound ultra-high-energy molecule, was previously proposed to explain a ∼40% efficiency of soft-X-ray generation in ∼0.05 keV/amu nanoparticle impact on solids. Here, the MIMS model has been extended and applied to interpreting the experimental K-shell X-ray satellite spectra for more than 40 years in keV-MeV/amu heavy-ion impact on solids. The binding energies of the K-shell MIMS of elements from Al to Ti were determined to be 80-200 eV. The successful extension of the model to the K-shell MIMS confirms that all elements in the periodic table and their combinations are subjected to the MIMS formation.

  10. Achieving clinical statement interoperability using R-MIM and archetype-based semantic transformations.

    Science.gov (United States)

    Kilic, Ozgur; Dogac, Asuman

    2009-07-01

    Effective use of electronic healthcare records (EHRs) has the potential to positively influence both the quality and the cost of health care. Consequently, sharing patient's EHRs is becoming a global priority in the healthcare information technology domain. This paper addresses the interoperability of EHR structure and content. It describes how two different EHR standards derived from the same reference information model (RIM) can be mapped to each other by using archetypes, refined message information model (R-MIM) derivations, and semantic tools. It is also demonstrated that well-defined R-MIM derivation rules help tracing the class properties back to their origins when the R-MIMs of two EHR standards are derived from the same RIM. Using well-defined rules also enable finding equivalences in the properties of the source and target EHRs. Yet an R-MIM still defines the concepts at the generic level. Archetypes (or templates), on the other hand, constrain an R-MIM to domain-specific concepts, and hence, provide finer granularity semantics. Therefore, while mapping clinical statements between EHRs, we also make use of the archetype semantics. Derivation statements are inferred from the Web Ontology Language definitions of the RIM, the R-MIMs, and the archetypes. Finally, we show how to transform Health Level Seven clinical statement instances to EHRcom clinical statement instances and vice versa by using the generated mapping definitions.

  11. Investigation of MIM Diodes for RF Applications

    KAUST Repository

    Khan, Adnan

    2015-05-01

    Metal Insulator Metal (MIM) diodes that work on fast mechanism of tunneling have been used in a number of very high frequency applications such as (Infra-Red) IR detectors and optical Rectennas for energy harvesting. Their ability to operate under zero bias condition as well as the possibility of realizing them through printing makes them attractive for (Radio Frequency) RF applications. However, MIM diodes have not been explored much for RF applications. One reason preventing their widespread RF use is the requirement of a very thin oxide layer essential for the tunneling operation that requires sophisticated nano-fabrication processes. Another issue is that the reliability and stable performance of MIM diodes is highly dependent on the surface roughness of the metallic electrodes. Finally, comprehensive RF characterization has not been performed for MIM diodes reported in the literature, particularly from the perspective of their integration with antennas as well as their rectification abilities. In this thesis, various metal deposition methods such as sputtering, electron beam evaporation, and Atomic Layer Deposition (ALD) are compared in pursuit of achieving low surface roughness. It is worth mentioning here that MIM diodes realized through ALD method have been presented for the first time in this thesis. Amorphous metal alloy have also been investigated in terms of their low surface roughness. Zinc-oxide has been investigated for its suitability as a thin dielectric layer for MIM diodes. Finally, comprehensive RF characterization of MIM diodes has been performed in two ways: 1) by standard S-parameter methods, and 2) by investigating their rectification ability under zero bias operation. It is concluded from the Atomic Force Microscopy (AFM) imaging that surface roughness as low as sub 1 nm can be achieved reliably from crystalline metals such as copper and platinum. This value is comparable to surface roughness achieved from amorphous alloys, which are non

  12. A New Explicit Algorithm for Bi-Phasic Mixture Flow in MIM

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Metal injection moulding (MIM) is a new technology to manufacture small intricate parts in large quantity. Numerical simulation plays an important role in its development. To predict the specific segregation effect in MIM injection, mixture theory is adopted to model the injection flow by a bi-phasic model. This model conducts to the solution of two-coupled Stokes equations. It is an extremely computational consuming solution in the scope of the traditional algorithms, which induce a serious challenge to cost-effectivity of the MIM simulation. Referred to some methods proposed by Lewis in mono-phasic simulation and the implicit algorithms in MIM simulation, a new explicit algorithm is proposed and realized to perform efficiently this type of bi-phasic flow. Numerically this algorithm is devised to perform the simulation in a fully uncoupled manner except for a global solution of the pressure field in each time step. The physical coupling is taken into account in a sequential pattern by fractional steps. This special algorithm does not need any iteration, so it is straightforward and robust, suitable for MIM simulation and other sorts of simulations for multi-phasic flow.

  13. Distance measurements between paramagnetic centers and a planar object by matrix Mims electron nuclear double resonance

    Science.gov (United States)

    Zänker, Paul-Philipp; Jeschke, Gunnar; Goldfarb, Daniella

    2005-01-01

    Frequency-domain electron nuclear double resonance (ENDOR), two time-domain electron nuclear double resonance techniques, and electron spin echo envelope modulation spectroscopy are compared with respect to their merit in measurements of small hyperfine couplings to nuclei with intermediate gyromagnetic ratio such as 31P. The frequency-domain Mims ENDOR experiment is found to provide the most faithful line shapes. In the limit of long electron-nuclear distances of more than 0.5 nm, sensitivity of this experiment is optimized by matching the first interpulse delay to the transverse relaxation time of the electron spins. In the same limit, Mims ENDOR efficiency scales inversely with the sixth power of distance. Hyperfine splittings as small as 33 kHz can be detected, corresponding to an electron-31P distance of 1 nm. In systems, where a certain kind of nuclei is distributed in a plane, measurements of intermolecular hyperfine couplings can be analyzed in terms of a distance of closest approach of a paramagnetic center to that plane. By applying this technique to spin-labeled lipids in a fully hydrated lipid bilayer it is found that for a fraction of lipids, chain tilt angles can be 25° larger than the mean tilt angle of the lipid chains. This model of all-trans hydrocarbon chains with a broad distribution of tilt angles is also consistent with orientation selection effects in high-field ENDOR spectra.

  14. MIMS circuit scrapbook V.I.

    CERN Document Server

    Mims, Forrest

    2000-01-01

    Here it is--a collection of Forrest Mims's classic work from the original Popular Electronics magazine! Using commonly available components and remarkable ingenuity, Forrest shows you how to build and experiment with circuits like these:analog computers color organs digital phase-locked loops frequency-to-voltage and voltage-to-frequency converters interval timers LED oscilloscopes light wave communicators magnetic field sensors optoelectronics pseudorandom number generators tone sequencers and much, much, more!

  15. Measurement and modeling of the molar heat capacity of the dicationic ionic liquid [ C4 (MIM) 2 ] [ PF6 ] 2%双阳离子型离子液体[C4(MIM)2][PF6]2的比热容测定及其模型化

    Institute of Scientific and Technical Information of China (English)

    杨许召; 王军; 孙新科

    2011-01-01

    利用差示扫描量热计(DSC)测定了双阳离子型离子液体1,1'-(丁烷-1,4-二基)-双(3-甲基-1H-咪唑鎓-1-基)双六氟磷酸盐([C4(MIM)2][PF6]2)在293.15~513.15 K温区内的摩尔比热容.结果表明,在293.15~363.15 K和398.15~513.15 K温区内,该化合物无相变及其他热异常现象发生,比热容随温度变化符合二次方程.在363.15~398.15 K温区内,该物质发生固-液熔化相变,其熔化温度、熔化焓及熔化熵分别为384.71 K、28.243kJ/mol和73.414 J/(K·mol).根据热力学函数关系式,计算出[C4(MIM)2][PF6]:相对于标准参考温度298.15K的热力学函数值.采用基团贡献法对液相区的热容进行了估算,结果表明,估算值与实验值符合很好.%The molar heat capacity of the dicationic ionic liquid 1, 1 '-( butane-l, 4-diyl)-bis(3-methyl-1 H- imidazolium-l-yl) dihexafluorophosphate ( [C4 (MIM)2 ] [ PF6 ]2 ) has been measured using a differential scanning calorimeter (DSC) at temperatures from 293. 15 K to 513. 15 K. No phase transition or other thermal anomaly was observed in the temperature ranges 293.15 -363.15 K and 398.15 -513.15 K, in which the molar heat capacities were fitted to two polynomials. The melting point, molar enthalpy and entropy of fusion were determined to be 384.71 K, 28.243 kJ/mol and 73.414 J/( K· mol), respectively. The thermodynamic functions of [ C4 ( MIM ) 2 ] [ PF6 ] 2 relative to the reference temperature 298. 15 K were derived based on the heat capacity data. A group contribution method was used to calculate the molar heat capacity of [ C4 ( MIM )2 ] [ PF6 ]2 in the liquid region. The results showed that the calculated values are in good agreement with the experimental values.

  16. Two solid-phase recycling method for basic ionic liquid [C4mim]Ac by macroporous resin and ion exchange resin from Schisandra chinensis fruits extract.

    Science.gov (United States)

    Ma, Chun-hui; Zu, Yuan-gang; Yang, Lei; Li, Jian

    2015-01-22

    In this study, two solid-phase recycling method for basic ionic liquid (IL) 1-butyl-3-methylimidazolium acetate ([C4mim]Ac) were studied through a digestion extraction system of extracting biphenyl cyclooctene lignans from Schisandra chinensis. The RP-HPLC detection method for [C4mim]Ac was established in order to investigate the recovery efficiency of IL. The recycling method of [C4mim]Ac is divided into two steps, the first step was the separation of lignans from the IL solution containing HPD 5000 macroporous resin, the recovery efficiency and purity of [C4mim]Ac achieved were 97.8% and 67.7%, respectively. This method cannot only separate the lignans from [C4mim]Ac solution, also improve the purity of lignans, the absorption rate of lignans in [C4mim]Ac solution was found to be higher (69.2%) than that in ethanol solution (57.7%). The second step was the purification of [C4mim]Ac by the SK1B strong acid ion exchange resin, an [C4mim]Ac recovery efficiency of 55.9% and the purity higher than 90% were achieved. Additionally, [C4mim]Ac as solvent extraction of lignans from S. chinensis was optimized, the hydrolysis temperature was 90°C and the hydrolysis time was 2h.

  17. MULTIMEDIA INTEGRATED MODELING FOR ENVIRONMENTAL PROTECTION: INTRODUCTION TO A COLLABORATIVE FRAMEWORK

    Science.gov (United States)

    The EPA's Office of Research and Development is embarking on a long term project to develop a Multimedia Integrated Modeling System (MIMS). The system will have capabilities to represent the transport and fate of nutrients and chemical stressors over multiple scales. MIMS will ...

  18. Field Continuous Measurement of Dissolved Gases with a CF-MIMS: Applications to the Physics and Biogeochemistry of Groundwater Flow.

    Science.gov (United States)

    Chatton, Eliot; Labasque, Thierry; de La Bernardie, Jérôme; Guihéneuf, Nicolas; Bour, Olivier; Aquilina, Luc

    2017-01-17

    In the perspective of a temporal and spatial exploration of aquatic environments (surface and groundwater), we developed a technique for field continuous measurements of dissolved gases with a precision better than 1% for N2, O2, CO2, He, Ar, 2% for Kr, 8% for Xe, and 3% for CH4, N2O and Ne. With a large resolution (from 1 × 10(-9) to 1 × 10(-2) ccSTP/g) and a capability of high frequency analysis (1 measure every 2 s), the CF-MIMS (Continuous Flow Membrane Inlet Mass Spectrometer) is an innovative tool allowing the investigation of a large panel of hydrological and biogeochemical processes in aquatic systems. Based on the available MIMS technology, this study introduces the development of the CF-MIMS (conception for field experiments, membrane choices, ionization) and an original calibration procedure allowing the quantification of mass spectral overlaps and temperature effects on membrane permeability. This study also presents two field applications of the CF-MIMS involving the well-logging of dissolved gases and the implementation of groundwater tracer tests with dissolved (4)He. The results demonstrate the analytical capabilities of the CF-MIMS in the field. Therefore, the CF-MIMS is a valuable tool for the field characterization of biogeochemical reactivity, aquifer transport properties, groundwater recharge, groundwater residence time and aquifer-river exchanges from few hours to several weeks experiments.

  19. Streamlining U.S. Army Military Installation Map (MIM) Production

    Science.gov (United States)

    2010-06-01

    Assurance Plans ( QAPs ). Serves as the standardized data structure across all Army training and testing installations. Once populated, this...produced NGA MIMs and supporting documentation. All aspects reflect the layout, fonts, and features which are common to MIMs. Based on SRP QAP (CIP

  20. Comparison of force fields on the basis of various model approaches--how to design the best model for the [CnMIM][NTf2] family of ionic liquids.

    Science.gov (United States)

    Köddermann, Thorsten; Reith, Dirk; Ludwig, Ralf

    2013-10-07

    In this contribution, we present two new united-atom force fields (UA-FFs) for 1-alkyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide [C(n)MIM][NTf(2)] (n=1, 2, 4, 6, 8) ionic liquids (ILs). One is parametrized manually, and the other is developed with the gradient-based optimization workflow (GROW). By doing so, we wanted to perform a hard test to determine how researchers could benefit from semiautomated optimization procedures. As with our already published all-atom force field (AA-FF) for [C(n)MIM][NTf(2)] (T. Köddermann, D. Paschek, R. Ludwig, ChemPhysChem- 2007, 8, 2464), the new force fields were derived to fit experimental densities, self-diffusion coefficients, and NMR rotational correlation times for the IL cation and for water molecules dissolved in [C(2)MIM][NTf(2)]. In the manual force field, the alkyl chains of the cation and the CF3 groups of the anion were treated as united atoms. In the GROW force field, only the alkyl chains of the cation were united. All other parts of the structures of the ions remained unchanged to prevent any loss of physical information. Structural, dynamic, and thermodynamic properties such as viscosity, cation rotational correlation times, and heats of vaporization calculated with the new force fields were compared with values simulated with the previous AA-FF and the experimental data. All simulated properties were in excellent agreement with the experimental values. Altogether, the UA-FFs are slightly superior for speed-up reasons. The UA-FF speeds up the simulation by about 100 % and reduces the demanded disk space by about 78 %. More importantly, real time and efforts to generate force fields could be significantly reduced by utilizing GROW. The real time for the GROW parametrization in this work was 2 months. Manual parametrization, in contrast, may take up to 12 months, and this is, therefore, a significant increase in speed, though it is difficult to estimate the duration of manual parametrization.

  1. Efficient removal of H2S at high temperature using the ionic liquid solutions of [C4mim]3PMo12O40-An organic polyoxometalate.

    Science.gov (United States)

    Ma, Yunqian; Liu, Xinpeng; Wang, Rui

    2017-06-05

    An innovative approach to H2S capture and sulfur recovery via liquid redox at high temperature has been developed using [C4mim]3PMo12O40 at temperatures ranging from 80 to 180°C, which is superior to the conventional water-based system with an upper limit of working temperature normally below 60°C. The ionic liquids used as solvents include [C4mim]Cl, [C4mim]BF4, [C4mim]PF6 and [C4mim]NTf2. Microscopic observation and turbidity measurement were used to investigate the dissolution of [C4mim]3PMo12O40 in the ionic liquids. Stabilization energy between H2S and the anion of ionic liquid as well as H2O was calculated to illustrate the interaction between H2S and the solvents. The cavity theory can be adopted to illustrate the mechanism for H2S absorption: the Cl(-) ion with small radius can be incorporated into the cavities of [C4mim]3PMo12O40, and interact with H2S strongly. The underlying mechanism for sulfur formation is the redox reaction between H2S and PMo12O40(3-). H2S can be oxidized to elemental sulfur and Mo(6+) is partly reduced during absorption, according to UV-vis and FTIR spectra. The [C4mim]3PMo12O40-[C4mim]Cl after reaction can be readily regenerated by air and thus enabling its efficient and repeatitive use. The absorbent of [C4mim]3PMo12O40-ionic liquid system provides a new approach for wet oxidation desulfurization at high temperature. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. ON THE USE OF NEXRAD STAGE IV DATA IN THE MULTIMEDIA MODELING OF POLLUTANT TRANSPORT

    Science.gov (United States)

    The Environmental Protection Agency (EPA) is designing the Multimedia Integrated Modeling System (MIMS) to model the cycling of pollutants and nutrients between the atmosphere and the earth's surface, including water bodies and groundwater. Our ability to accurately model both ...

  3. Metastable innershell molecular state (MIMS) III: The universal binding energy and bond length of the homonucleus K-shell MIMS

    Science.gov (United States)

    Bae, Young K.

    2016-03-01

    This paper reports the discovery of a universal Z2-dependency of the binding energy of the homonucleus K-shell MIMS (K-MIMS: Metastable Innershell Molecular State bound by K-shell electrons), which has been established by analyzing extensive existing experimental data over several decades. An intuitive analytical theory on the K-MIMS has been developed for the homologous molecules to the He*2 excimer, which elucidates the universal Z-dependent behavior of the K-MIMS. The theory predicts a 1 / Z-dependency of the K-MIMS bond length, which is in agreement with the quasimolecule sizes estimated from the x-ray generation cross-sections in H-like Bi82+ and U91+ impact on Au solids.

  4. [Study on biocompatibility of MIM 316L stainless steel].

    Science.gov (United States)

    Wang, Guohui; Zhu, Shaihong; Li, Yiming; Zhao, Yanzhong; Zhou, Kechao; Huang, Boyun

    2007-04-01

    This study was aimed to evaluate the biocompatibility of metal powder injection molding (MIM) 316L stainless steel. The percentage of S-period cells was detected by flow cytometry after L929 cells being incubated with extraction of MIM 316L stainless steel, and titanium implant materials for clinical application were used as control. In addition, both materials were implanted in animals and the histopathological evaluations were carried out. The statistical analyses show that there are no significant differences between the two groups (P > 0.05), which demonstrate that MIM 316L stainless steel has good biocompatibility.

  5. Field continuous measurement of dissolved gases with a CF-MIMS: Applications to the physics and biogeochemistry of groundwater flow

    Science.gov (United States)

    Chatton, Eliot; Labasque, Thierry; de La Bernardie, Jérôme; Guihéneuf, Nicolas; Bour, Olivier; Aquilina, Luc

    2017-04-01

    In the perspective of a temporal and spatial exploration of aquatic environments (surface and ground water), we developed a technique for precise field continuous measurements of dissolved gases (N2, O2, CO2, CH4, N2O, H2, He, Ne, Ar, Kr, Xe). With a large resolution (from 1×10-9 to 1×10-2 ccSTP/g) and a capability of high frequency analysis (1 measure every 2 seconds), the CF-MIMS (Continuous Flow Membrane Inlet Mass Spectrometer) is an innovative tool allowing the investigation of a large panel of hydrological and biogeochemical processes in aquatic systems. Based on the available MIMS technology, this study introduces the development of the CF-MIMS (conception for field experiments, membrane choices, ionisation) and an original calibration procedure allowing the quantification of mass spectral overlaps and temperature effects on membrane permeability. This study also presents two field applications of the CF-MIMS (Chatton et al, 2016) involving the well-logging of dissolved gases and the implementation of groundwater tracer tests with dissolved 4He. The results demonstrate the analytical capabilities of the CF-MIMS in the field. Therefore, the CF-MIMS is a valuable tool for the field characterisation of biogeochemical reactivity, aquifer transport properties, groundwater recharge, groundwater residence time and aquifer-river exchanges from few hours to several weeks experiments. Eliot Chatton, Thierry Labasque, Jérôme de La Bernardie, Nicolas Guihéneuf, Olivier Bour and Luc Aquilina; Field Continuous Measurement of Dissolved Gases with a CF-MIMS: Applications to the Physics and Biogeochemistry of Groundwater Flow; Environmental Science & Technology, in press, 2016.

  6. [Schimmelpenning-Feuerstein-Mims syndrome: a case report].

    Science.gov (United States)

    Bahloul, E; Abid, I; Masmoudi, A; Makni, S; Kamoun, F; Boudawara, T; Triki, C; Turki, H

    2015-11-01

    Schimmelpenning-Feuerstein-Mims syndrome (SFM) is a congenital neurocutaneous disorder characterized by the association of nevus sebaceous with extracutaneous abnormalities. We report a new case of Schimmelpenning-Feuerstein-Mims with aortic coarctation and drug-resistant West syndrome. This case emphasizes the importance of exploring and monitoring patients with nevus sebaceous in order to diagnose associated anomalies. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  7. Materials and process development for the monolithic interconnected module (MIM) InGaAs/InP TPV cells

    Energy Technology Data Exchange (ETDEWEB)

    Fatemi, N.S.; Jenkins, P.P.; Hoffman, R.W. Jr.; Weizer, V.G. [Essential Research, Inc., Cleveland, OH (United States); Wilt, D.M. [National Aeronautics and Space Administration, Cleveland, OH (United States). Lewis Research Center; Murray, C.S.; Riley, D. [Westinghouse Electric Corp., West Mifflin, PA (United States)

    1997-06-01

    Four major components of a thermophotovoltaic (TPV) energy conversion system are a heat source, a graybody or a selective emitter, spectrum shaping elements such as filters, and photovoltaic (PV) cells. One approach to achieving a high voltage/low current configuration is to fabricate a device, where small area PV cells are monolithically series connected. The authors have termed this device a monolithic interconnected module (MIM). A MIM device has other advantages over conventional one-junction cells, such as simplified array interconnections and heat-sinking, and radiation recycling capability via a back surface reflector (BSR). The authors confine the contents of this article to the MIM materials, process development, and some optical results. The successful fabrication of InGaAs/InP MIM devices entails the development and optimization of several key components and processes. These include: isolation trench via geometry, selective chemical etching, contact and interconnect metallization, dielectric isolation barrier, back surface reflector (BSR), and anti-reflection (AR) coating. The selection, development, and testing of the materials and processes described above for MIM fabrication will be described.

  8. Influence of thermal debinding on the final properties of Fe–Si soft magnetic alloys for metal injection molding (MIM)

    Energy Technology Data Exchange (ETDEWEB)

    Páez-Pavón, A.; Jiménez-Morales, A. [Dpto. Ciencia e Ing. de materiales e Ing. Química, Universidad Carlos III de Madrid, 28911 Leganés, Madrid (Spain); Santos, T.G. [UNIDEMI, Departamento de Engenharia Mecânica e Industrial, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica (Portugal); Quintino, L. [Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa (Portugal); Torralba, J.M. [Dpto. Ciencia e Ing. de materiales e Ing. Química, Universidad Carlos III de Madrid, 28911 Leganés, Madrid (Spain)

    2016-10-15

    Metal injection molding (MIM) may be used to produce soft magnetic materials with optimal mechanical and magnetic properties. Unlike other techniques, MIM enables the production of complex and small Fe–Si alloy parts with silicon contents greater than 3% by weight. In MIM process development, it is critical to design a proper debinding cycle not only to ensure complete removal of the binder system but also to obtain improved properties in the final part. This work is a preliminary study on the production of Fe-3.8Si soft magnetic parts by MIM using pre-alloyed powders and a non-industrialized binder. Two different heating rates during thermal debinding were used to study their effect on the final properties of the part. The final properties of the sintered parts are related to thermal debinding. It has been demonstrated that the heating rate during thermal debinding has a strong influence on the final properties of Fe–Si soft magnetic alloys. - Highlights: • The properties of MIM Fe-Si alloy are influenced by the debinding heating rate. • The slow debinding led to a lower porosity, lower oxygen content and grain growth. • The magnetization of the sintered samples improved after a slow thermal debinding.

  9. Thermal Preconditioning of MIMS Type K Thermocouples to Reduce Drift

    Science.gov (United States)

    Webster, E. S.

    2017-01-01

    Type K thermocouples are the most widely used temperature sensors in industry and are often used in the convenient mineral-insulated metal-sheathed (MIMS) format. The MIMS format provides almost total immunity to oxide-related drift in the 800°C-1000°C range. However, crystalline ordering of the atomic structure causes drift in the range 200°C-600°C. Troublesomely, the effects of this ordering are reversible, leading to hysteresis in some applications. Typically, MIMS cable is subjected to a post-manufacturing high-temperature recrystallization anneal to remove cold-work and place the thermocouple in a `known state.' However, variations in the temperatures and times of these exposures can lead to variations in the `as-received state.' This study gives guidelines on the best thermal preconditioning of 3 mm MIMS Type K thermocouples in order to minimize drift and achieve the most reproducible temperature measurements. Experimental results demonstrate the consequences of using Type K MIMS thermocouples in different states, including the as-received state, after a high-temperature recrystallization anneal and after preconditioning anneals at 200°C, 300°, 400°C and and 500°C. It is also shown that meaningful calibration is possible with the use of regular preconditioning anneals.

  10. MIM-Induced Membrane Bending Promotes Dendritic Spine Initiation.

    Science.gov (United States)

    Saarikangas, Juha; Kourdougli, Nazim; Senju, Yosuke; Chazal, Genevieve; Segerstråle, Mikael; Minkeviciene, Rimante; Kuurne, Jaakko; Mattila, Pieta K; Garrett, Lillian; Hölter, Sabine M; Becker, Lore; Racz, Ildikó; Hans, Wolfgang; Klopstock, Thomas; Wurst, Wolfgang; Zimmer, Andreas; Fuchs, Helmut; Gailus-Durner, Valérie; Hrabě de Angelis, Martin; von Ossowski, Lotta; Taira, Tomi; Lappalainen, Pekka; Rivera, Claudio; Hotulainen, Pirta

    2015-06-22

    Proper morphogenesis of neuronal dendritic spines is essential for the formation of functional synaptic networks. However, it is not known how spines are initiated. Here, we identify the inverse-BAR (I-BAR) protein MIM/MTSS1 as a nucleator of dendritic spines. MIM accumulated to future spine initiation sites in a PIP2-dependent manner and deformed the plasma membrane outward into a proto-protrusion via its I-BAR domain. Unexpectedly, the initial protrusion formation did not involve actin polymerization. However, PIP2-dependent activation of Arp2/3-mediated actin assembly was required for protrusion elongation. Overexpression of MIM increased the density of dendritic protrusions and suppressed spine maturation. In contrast, MIM deficiency led to decreased density of dendritic protrusions and larger spine heads. Moreover, MIM-deficient mice displayed altered glutamatergic synaptic transmission and compatible behavioral defects. Collectively, our data identify an important morphogenetic pathway, which initiates spine protrusions by coupling phosphoinositide signaling, direct membrane bending, and actin assembly to ensure proper synaptogenesis. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. Reliability characterization of MEMS switch using MIM test structures

    Directory of Open Access Journals (Sweden)

    Vaibhav Dubey

    2014-12-01

    Full Text Available Silicon nitride thin film dielectrics are used in capacitive radio frequency micro-electromechanical systems (MEMS switches since they provide a low insertion loss, good isolation, and low return loss. The lifetime of these switches is believed to be adversely affected by charge trapping in the silicon nitride. The goal of this research was to characterize Si3N4-based MIM (Metal–Insulator–Metal capacitors to describe the mechanisms responsible for the conduction and trapping behaviour in MEMS switches. The silicon nitride films were deposited by ICP chemical vapour deposition at room temperatures. The upper Si3N4 layer was removed by the reactive ion etching process (RIE in order to provide contact paths to the bottom electrode. In the near-stoichiometric films, different electrical characterizations were performed to study dependence of the leakage current on different electrical parameters. It was concluded that the Poole–Frenkel mechanism dominated the conduction in the silicon nitride films at high fields.

  12. Plasma-Charging Damage of Floating MIM Capacitors

    NARCIS (Netherlands)

    Wang, Zhichun; Ackaert, Jan; Salm, Cora; Kuper, Fred G.; Tack, Marnix; De Backer, Eddy; Coppens, Peter; De Schepper, Luc; Vlachakis, Basil

    2004-01-01

    In this paper, the mechanism of plasma-charging damage (PCD) of metal-insulator-metal (MIM) capacitors as well as possible protection schemes are discussed. A range of test structures with different antennas simulating interconnect layout variations have been used to investigate the mechanism of PCD

  13. Phacomatosis pigmentokeratotica or the Schimmelpenning-Feuerstein-Mims syndrome?

    Science.gov (United States)

    Gamayunov, Boris N; Korotkiy, Nikolay G; Baranova, Elena E

    2016-06-01

    Cutaneous symptoms in some patients with clinical picture of Schimmelpenning-Feuerstein-Mims syndrome can include a speckled lentiginous nevus, also known as nevus spilus. Recent investigations show that somatic heterozygous HRAS mutations are present in the sebaceous and speckled lentiginous nevus tissues of patients with combination of two nevi.

  14. Metal Injection Molding (MIM of Magnesium and Its Alloys

    Directory of Open Access Journals (Sweden)

    Martin Wolff

    2016-05-01

    Full Text Available Current research has highlighted that magnesium and its alloys as biodegradable material are highly suitable for biomedical applications. The new material fully degrades into nontoxic elements and offers material properties matching those of human bone tissue. As biomedical implants are rather small and complex in shape, the metal injection molding (MIM technique seems to be well suited for the near net shape mass production of such parts. Furthermore, MIM of Mg-alloys is of high interest in further technical fields. This study focusses on the performance of MIM-processing of magnesium alloy powders. It includes Mg-specific development of powder blending, feedstock preparation, injection molding, solvent and thermal debinding and final sintering. Even though Mg is a highly oxygen-affine material forming a stable oxide layer on each particle surface, the material can be sintered to nearly dense parts, providing mechanical properties matching those of as cast material. An ultimate tensile strength of 142 MPa, yield strength of 67 MPa, elastic modulus of 40 GPa and 8% elongation at fracture could be achieved using novel organic polymer binders for the feedstock preparation. Thus, first implant demonstrator parts could be successfully produced by the MIM technique.

  15. Plasma-charging damage of floating MIM capacitors

    NARCIS (Netherlands)

    Wang, Zhichun; Ackaert, Jan; Salm, Cora; Kuper, F.G.; Tack, Marnix; de Backer, Eddy; Coppens, Peter; De Schepper, Luc; Vlachakis, Basil

    2004-01-01

    In this paper, the mechanism of plasma-charging damage (PCD) of metal-insulator-metal (MIM) capacitors as well as possible protection schemes are discussed. A range of test structures with different antennas simulating interconnect layout variations have been used to investigate the mechanism of PCD

  16. Raman Spectroscopy and Ab-Initio Model Calculations on Ionic Liquids

    DEFF Research Database (Denmark)

    Berg, Rolf W.

    2007-01-01

    spectroscopy and ab-initio molecular orbital calculations. A discussion is given, based mainly on some recent FT-Raman spectroscopic results on the model ionic liquid system of 1-butyl-3-methylimidazolium ([C4mim][X]) salts. The rotational isomerism of the [C4mim]þ cation is described: the presence of anti...... will be applied to many more systems in the future. A few examples will be discussed....

  17. Continuous in-situ monitoring of dissolved gases for the characterization of the Critical Zone with a MIMS

    Science.gov (United States)

    Chatton, Eliot; Labasque, Thierry; Aquilina, Luc; de la Bernardie, Jérôme; Guihéneuf, Nicolas

    2016-04-01

    In the perspective of a temporal and spatial exploration of the Critical Zone, we developed an in situ monitoring instrument for continuous dissolved gas analysis (N2, O2, CO2, CH4, He, Ne, Ar, Kr, Xe). With a large resolution (5 orders of magnitude) and a capability of high frequency multi-tracer analysis (1 gas every 1.5 seconds), the MIMS (Membrane Inlet Mass Spectrometer) is an innovative tool allowing the investigation of a large panel of physical and biogeochemical processes. First of all, this study presents the results of groundwater tracer tests using dissolved gases in order to evaluate transport properties of a fractured media in Brittany, France (Ploemeur, ORE H+). The tracer test experiment showed that the MIMS is perfectly suitable for field work. The instrument provides precise measurements accurate enough to produce breakthrough curves during groundwater tracer tests. The results derived from 4He data gives transport parameters in good agreement with the results obtained with a fluorescent tracer. Combined with a pump and a multi-parameter probe, the MIMS is also capable to perform accurate dissolved gases well-logs allowing a real-time estimation of recharge conditions (temperature, excess air), aquifer stratification, redox conditions and groundwater residence time by 4He dating. Therefore, the MIMS is a valuable tool for in situ characterization of biogeochemical reactivity in aquatic systems, the determination of aquifer transport properties, the monitoring of groundwater recharge conditions and the characterization of aquifer-river exchanges.

  18. Influence of thermal debinding on the final properties of Fe-Si soft magnetic alloys for metal injection molding (MIM)

    Science.gov (United States)

    Páez-Pavón, A.; Jiménez-Morales, A.; Santos, T. G.; Quintino, L.; Torralba, J. M.

    2016-10-01

    Metal injection molding (MIM) may be used to produce soft magnetic materials with optimal mechanical and magnetic properties. Unlike other techniques, MIM enables the production of complex and small Fe-Si alloy parts with silicon contents greater than 3% by weight. In MIM process development, it is critical to design a proper debinding cycle not only to ensure complete removal of the binder system but also to obtain improved properties in the final part. This work is a preliminary study on the production of Fe-3.8Si soft magnetic parts by MIM using pre-alloyed powders and a non-industrialized binder. Two different heating rates during thermal debinding were used to study their effect on the final properties of the part. The final properties of the sintered parts are related to thermal debinding. It has been demonstrated that the heating rate during thermal debinding has a strong influence on the final properties of Fe-Si soft magnetic alloys.

  19. Effects of surfactant on properties of MIM feedstock

    Institute of Scientific and Technical Information of China (English)

    LI Yi-min; LIU Xiang-quan; LUO Feng-hua; YUE Jian-ling

    2007-01-01

    Effects of the surfactant for improving the properties of MIM feedstock were investigated. Feedstocks were prepared by 17-4PH stainless steel(SS) powder and paraffin wax-based binder containing different contents of stearic acid(SA) as the surfactant. The viscosity of the feedstock decreases significantly when the SA is added. Besides, the wetting angle of the binder against the 17-4PH SS powder decreases greatly and the critical solid loading increases with the adding of the SA. Fourier transformation infrared spectroscopy(FTIR) analysis was used to prove the interaction between the SA and the 17-4PH SS powder. Chemical bonding is found on the surface of 17-4PH SS powder after mixing and it helps a lot to enhance the interacting force between the binder and the powder. Then an adsorbing model was adopted to estimate the least content of the surfactant that formed a monolayer adsorption on the mono-sized spherical powder (with smooth surface). The least content of the surfactant is calculated to be 0.19%. Whereas, the experiments indicate that about 5% is the optimal value to improve the properties of the feedstock. The reason may come from two aspects: firstly, the powders used in current experiment are not all mono-sized spheres and the coarse surface of the powder has a great effect on the adsorptive capacity of the powder; secondly, multilayer adsorption is likely to occur on the powder surface, which will also increase the adsorptive capacity.

  20. Metal Injection Molding (MIM of NdFeB Magnets

    Directory of Open Access Journals (Sweden)

    Hartwig T.

    2014-07-01

    Full Text Available Due to the increased and unstable prices for Rare Earth elements there are activities to develop alternative hard magnetic materials. Reducing the amount of material necessary to produce complex sintered NdFeB magnets can also help to reduce some of the supply problem. Metal Injection Molding (MIM is able to produce near net shape parts and can reduce the amount of finishing to achieve final geometry. Although MIM of NdFeB has been patented and published fairly soon after the development of the NdFeB magnets there has never been an industrial production. This could be due to the fact that MIM was very young at that time and hardly developed. Thus, the feasibility of the process needs to be revaluated. This paper presents results of our work on determining the process parameters influencing the magnetic properties of the sintered magnets as well as the shrinkage during processing. The role of binder and powder loading on the alignment of the particles as well as on the carbon and oxygen contamination was examined.

  1. Delicate polydimethylsiloxane hollow fibre membrane interfaces for condensed phase membrane introduction mass spectrometry (CP-MIMS).

    Science.gov (United States)

    Willis, Megan D; Duncan, Kyle D; Krogh, Erik T; Gill, Chris G

    2014-04-15

    On-line analytical techniques such as condensed phase membrane introduction mass spectrometry (CP-MIMS) permit direct and rapid analyte measurements in complex samples. Direct, rapid analytical methods are desirable because they eliminate potential contamination and/or dilution from sample workup steps, facilitate rapid sample screening and allow 'real-time' monitoring applications. PDMS hollow fibre membrane (HFM) flow cell interfaces (215 µm, 35 µm, and 0.5 µm thick composite) were coupled with an electrospray ionization (ESI) triple quadrupole mass spectrometer. A simultaneous push/pull methanol acceptor phase delivery system and membrane mounting via epoxy potting ensured that the delicate membranes were not ruptured during construction or sample measurements. Both flow cell and direct insertion 'J-Probe' interfaces using the 0.5 µm thick composite PDMS HFM were utilized for direct naphthenic acid measurements. Delicate HFM CP-MIMS interfaces were used for the rapid screening and continuous, on-line monitoring of carboxylic acids and hydroxylated compounds directly in complex sample matrices under ambient conditions at pptr - ppb detection limits. Push/pull acceptor phase (methanol) delivery maintained ambient hydrostatic pressures within the HFMs, improving ESI stability and analytical sensitivity, especially with stopped acceptor flow operation. Signal response times less than 2 min were achieved for thin, composite PDMS HFMs at 30°C. The continuous monitoring of naphthenic acid degradation was demonstrated. Delicate PDMS HFM CP-MIMS interfaces were developed and used for the direct, on-line detection of low volatility, polar analytes in complex aqueous samples. Composite PDMS HFM interfaces yielded the best overall analytical performance improvements, and were used to demonstrate the direct measurement of naphthenic acids in complex aqueous samples. Copyright © 2014 John Wiley & Sons, Ltd.

  2. Parameter Optimization Of Natural Hydroxyapatite/SS316l Via Metal Injection Molding (MIM)

    Science.gov (United States)

    Mustafa, N.; Ibrahim1, M. H. I.; Amin, A. M.; Asmawi, R.

    2017-01-01

    Metal injection molding (MIM) are well known as a worldwide application of powder injection molding (PIM) where as applied the shaping concept and the beneficial of plastic injection molding but develops the applications to various high performance metals and alloys, plus metal matrix composites and ceramics. This study investigates the strength of green part by using stainless steel 316L/ Natural hydroxyapatite composite as a feedstock. Stainless steel 316L (SS316L) was mixed with Natural hydroxyapatite (NHAP) by adding 40 wt. % Low Density Polyethylene and 60 %wt. Palm Stearin as a binder system at 63 wt. % powder loading consist of 90 % wt. of SS316 L and 10 wt. % NHAP prepared thru critical powder volume percentage (CPVC). Taguchi method was functional as a tool in determining the optimum green strength for Metal Injection Molding (MIM) parameters. The green strength was optimized with 4 significant injection parameter such as Injection temperature (A), Mold temperature (B), Pressure (C) and Speed (D) were selected throughout screening process. An orthogonal array of L9 (3)4 was conducted. The optimum injection parameters for highest green strength were established at A1, B2, C0 and D1 and where as calculated based on Signal to Noise Ratio.

  3. Identification of radiolytic products of [C4mim][PF6] underγ-irradiation

    Institute of Scientific and Technical Information of China (English)

    敖银勇; 徐敏; 彭静; 李久强; 翟茂林; 吴国忠

    2015-01-01

    The trace water-soluble radiolytic products of neat 1-butyl-3-methylimidazolium hexafluorophosphate ([C4mim][PF6]) were identified by analysing water-washed samples of γ-irradiated ionic liquids. HF and difluorophosphinic acid were confirmed as the main radiolytic products of [C4mim][PF6], and their radiation chemical yields were quantified by 19F NMR (G(F−)=0.14 µmol/J, G(HOP(O)F2)=0.053 µmol/J). Com-pared to [C4mim][NTf2], [C4mim][PF6] shows better radiation stability.

  4. Effects of polarizability on the structural and thermodynamics properties of [C{sub n}mim][Gly] ionic liquids (n = 1–4) using EEM/MM molecular dynamic simulations

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Yang; Hu, Na; Yue, Lili; Wei, Lihong; Guan, Wei [Key Laboratory of Green Synthesis and Preparative Chemistry of Advanced Materials, College of Chemistry, Liaoning University, Shenyang 110036 (China)

    2015-02-14

    An extended electronegativity equalization method/molecular mechanics (EEM/MM) model for ionic liquids is used to investigate the structures and properties of 1-alkyl-3-methylimidazolium glycine ionic liquids [C{sub n}mim][Gly] (n = 1–4) with alkyl substituents of different lengths. The EEM/MM model describes the electrostatic interactions of atoms and their changes in different ambient environments. This property is the most outstanding characteristic of the model. EEM parameters (i.e., valence electronegativities and valence hardness parameters) are calibrated using linear regression and least-squares methods, which can accurately predict the gas-phase properties of [C{sub n}mim]{sup +}, [Gly]{sup −}, and [C{sub n}mim][Gly] ion pairs. We utilize the EEM/MM force field to systematically investigate the effects of polarizability on the accuracy of [C{sub n}mim][Gly] properties predicted through the molecular dynamic simulations. EEM/MM explicitly describes the atom-based polarizability of [C{sub n}mim][Gly]; thus, the densities, enthalpies of vaporization, self-diffusion coefficients, and conductivities of the [C{sub n}mim][Gly] are consistent with the experimental values. The calculated radial distribution functions provide a mechanistic understanding of the effects of polarizability on ionic aggregations in amino acid ionic liquids. The effects of alkyl chain length on the diffusion coefficient and conductivity are also discussed.

  5. Molecularly imprinted membranes (MIMs) for selective removal of polychlorinated biphenyls (PCBs) in environmental waters: fabrication and characterization.

    Science.gov (United States)

    Mkhize, Dennis S; Nyoni, Hlengilizwe; Quinn, Laura P; Mamba, Bhekie B; Msagati, Titus A M

    2017-04-01

    Molecularly imprinted membranes (MIMs) with selective removal properties for polychlorinated biphenyls (PCBs) were prepared through the phase inversion technique. The MIMs were obtained from casting the viscous solutions of molecularly imprinted polymers (MIPs), polysulfone (PSf), and N-methyl-2-pyrrolidone (NMP) as the casting solvent. Different membranes were prepared at different concentration of MIPs and PSf. The resulting MIMs were characterized by atomic force microscope (AFM), scanning electron microscope (SEM), and Fourier transform infrared spectroscopy (FTIR). Moreover, the performance of the membranes was evaluated by determining and interpreting the rejection (%), flux (F), permeability coefficient (P), permselectivity factor ( α (')PCB/DDT or anthracene), and enrichment factors of PCBs, dichlorodiphenyltrichloroethane (p,p'-DDT), and anthracene from model contaminated water using the dead-end filtration cell. Molecularly imprinted membrane prepared with 18 wt% PSf and 20 wt% MIP 4 exhibited a well-defined porous structure, which was accompanied by enhanced PCB enrichment. Furthermore, molecularly imprinted membrane showed good enrichment factors for PCBs even from spiked natural water samples of Hartbeespoort dam.

  6. Equation of state modelling of systems with ionic liquids: Literature review and application with the Cubic Plus Association (CPA) model

    DEFF Research Database (Denmark)

    Maia, Filipa Meireles; Tsivintzelis, Ioannis; Rodriguez, Oscar

    2012-01-01

    -ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([C2mim][NTf2]) and 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide([C4mim][NTf2]). The first step was to study an adequate approach for the determination of pure component parameters for the ionic liquids. The parameters were...... obtained by fitting the predictions of the model to experimental vapour pressure and liquid density data. The parameters provide a good description of both experimental vapour pressures and liquid density, with maximum percentage deviations of respectively 8.9 and 1.3% for [C2mim][NTf2] and 5.7 and 0.......5% for [C4mim][NTf2]. Different sets of pure component parameters for each ionic liquid were considered and their suitability to describe the behaviour of ionic liquids was evaluated by modelling the vapour–liquid equilibria (VLE) of mixtures with CO2 and the liquid–liquid equilibria (LLE) with water...

  7. X-ray computed microtomography studies of MIM and DPR parts

    CSIR Research Space (South Africa)

    Muchavi, Noluntu S

    2016-10-01

    Full Text Available of the evolution of porosity in metal injection moulding (MIM) and direct powder rolling (DPR) products. 17-4 PH stainless steel (as-moulded, as-debound and sintered) dog-bone samples produced via MIM and Ti-HDH strips (as-rolled and sintered) produced via DPR...

  8. MIM, a Potential Metastasis Suppressor Gene in Bladder Cancer

    Directory of Open Access Journals (Sweden)

    Young-Goo Lee

    2002-01-01

    Full Text Available Using a modified version of the mRNA differential display technique, five human bladder cancer cell lines from low grade to metastatic were analyzed to identify differences in gene expression. A 316-bp cDNA (C11300 was isolated that was not expressed in the metastatic cell line TccSuP. Sequence analysis revealed that this gene was identical to KIAA 0429, has a 5.3-kb transcript that mapped to 8824.1. The protein is predicted to be 356 amino acids in size and has an actin-binding WH2 domain. Northern blot revealed expression in multiple normal tissues, but none in a metastatic breast cancer cell line (SKBR3 or in metastatic prostatic cancer cell lines (LNCaP, PC3. We have named this gene Missing in Metastasis (MIM and our data suggest that it may be involved in cytoskeletal organization.

  9. Realizing of plasmon Fano resonance with a metal nanowall moving along MIM waveguide

    Science.gov (United States)

    Chen, Fang; Yao, Duanzheng

    2016-06-01

    A larger number of complicated plasmonic nanostructures have been realized to exhibit Fano interference. In this paper, we demonstrate a simple nanostructure, side coupled waveguide resonator system with a metal nanowall located in the metal-insulator-metal waveguide (MIM), which can also achieve multiple plasmonic Fano resonance. In the proposed nanostructure, the asymmetric line shape originates from the interference between the slot resonator and the new resonator. Therefore, the Fano line shape can be actively controlled by the phase difference of the two resonators and the thickness of the metal nanowall. A scattering matrix method is used to calculate the transmission spectra. Results obtained by the scattering matrix theory are consistent with those from the finite-difference time-domain simulations (FDTD). Moreover, Fano resonances in the proposed structure show high sensitivity, which may have important application in plasmonic nanosensor and modulator.

  10. Investigation of high-temperature charge transport mechanism in Al-Gd2O3-Al-based metal-insulator-metal (MIM) structure

    Science.gov (United States)

    Wasiq, M. F.; Mahmood, Khalid; Aen, Faiza; Warsi, Muhammad Farooq; Khan, Muhammad Azhar

    2016-12-01

    In this paper, the charge conduction mechanism at high temperature in Al-Gd2O3 (MIM) structure has been investigated by performing temperature-dependent current-voltage measurements in the temperature range 280-390 K. MIM structure is realized by electron beam evaporation system where thin films of Gd2O3 (40, 60 and 80 nm) and Al metal on both sides of dielectric film were deposited on glass substrate. The possibility of different transport mechanisms has been testified by plotting various graphs. The nonlinear behavior of Ln V versus Ln I and V 1/2 versus Ln V/ I graphs ruled out the possibility of space-charge-limited conduction (SCLC) and Poole-Frenkel mechanism in Al-Gd2O3-Al MIM structure. The straight lines Ln I- V 1/2 graphs at various temperatures confirmed that Schottky emission is the dominant transport mechanism in Al-Gd2O3-Al structure. The calculated values of field barrier lowering coefficient at different measurement temperatures were in good agreement with the theoretical prediction confirming conduction is via Schottky emission. The field-dependent Ln( I/ T 2) versus 1000/ T plots were obeyed a linear relationship according to Schottky emission theory. Furthermore, the dielectric thickness dependence room-temperature current-voltage characteristics of Al-Gd2O3-Al MIM structure were showed strong dependence of current on dielectric film thickness according to Schottky emission theory of conduction current.

  11. Improved detection of low vapor pressure compounds in air by serial combination of single-sided membrane introduction with fiber introduction mass spectrometry (SS-MIMS-FIMS).

    Science.gov (United States)

    Cotte-Rodríguez, Ismael; Handberg, Eric; Noll, Robert J; Kilgour, David P A; Cooks, R Graham

    2005-05-01

    The use of two methods in tandem, single-sided membrane introduction mass spectrometry (SS-MIMS) and fiber introduction mass spectrometry (FIMS), is presented as a technique for field analysis. The combined SS-MIMS-FIMS technique was employed in both a modified commercial mass spectrometer and a miniature mass spectrometer for the selective preconcentration of the explosive simulant o-nitrotoluene (ONT) and the chemical warfare agent simulant, methyl salicylate (MeS), in air. A home-built FIMS inlet was fabricated to allow introduction of the solid-phase microextraction (SPME) fiber into the mass spectrometer chamber and subsequent desorption of the trapped compounds using resistive heating. The SS-MIMS preconcentration system was also home-built from commercial vacuum parts. Optimization experiments were done separately for each preconcentration system to achieve the best extraction conditions prior to use of the two techniques in combination. Improved limits of detection, in the low ppb range, were observed for the combination compared to FIMS alone, using several SS-MIMS preconcentration cycles. The SS-MIMS-FIMS response for both instruments was found to be linear over the range 50 to 800 ppb. Other parameters studied were absorption time profiles, effects of sample flow rate, desorption temperature, fiber background, memory effects, and membrane fatigue. This simple, sensitive, accurate, robust, selective, and rapid sample preconcentration and introduction technique shows promise for field analysis of low vapor pressure compounds, where analyte concentrations will be extremely low and the compounds are difficult to extract from a matrix like air.

  12. Model Systems

    Directory of Open Access Journals (Sweden)

    Francisco Rodríguez-Trelles

    1998-12-01

    Full Text Available Current efforts to study the biological effects of global change have focused on ecological responses, particularly shifts in species ranges. Mostly ignored are microevolutionary changes. Genetic changes may be at least as important as ecological ones in determining species' responses. In addition, such changes may be a sensitive indicator of global changes that will provide different information than that provided by range shifts. We discuss potential candidate systems to use in such monitoring programs. Studies of Drosophila subobscura suggest that its chromosomal inversion polymorphisms are responding to global warming. Drosophila inversion polymorphisms can be useful indicators of the effects of climate change on populations and ecosystems. Other species also hold the potential to become important indicators of global change. Such studies might significantly influence ecosystem conservation policies and research priorities.

  13. Quantitative imaging of selenoprotein with multi-isotope imaging mass spectrometry (MIMS).

    Science.gov (United States)

    Tang, Shiow-Shih; Guillermier, Christelle; Wang, Mei; Poczatek, Joseph Collin; Suzuki, Noriyuki; Loscalzo, Joseph; Lechene, Claude

    2014-11-01

    Multi-isotope imaging mass spectrometry (MIMS) allows high resolution quantitative imaging of protein and nucleic acid synthesis at the level of a single cell using stable isotope labels. We employed MIMS to determine the compartmental localization of selenoproteins tagged with stable isotope selenium compounds in human aortic endothelial cells (HAEC), and to compare the efficiency of labeling (to determine the ideal selenium source) from these compounds: [(82)Se]-selenite, [(77)Se]-seleno-methionine, and [(76)Se]-methyl-selenocysteine. We found that all three selenium sources appear to be localized in the nucleus as well as in the cytoplasm in HAEC. Seleno-methionine appears to be a better source for (seleno)protein synthesis. For MIMS detection, we compared freeze-drying to thin layer vs. thin sectioning for sample preparation. MIMS provides a unique and novel way to dissect selenoprotein synthesis in cells.

  14. Chronic effects of the ionic liquid [C4mim][Cl] towards the microalga Scenedesmus quadricauda.

    Science.gov (United States)

    Deng, Yun; Beadham, Ian; Wu, Jie; Chen, Xiao-Di; Hu, Lan; Gu, Jun

    2015-09-01

    Chronic effects of the ionic liquid [C4mim][Cl] (mp 73 °C) towards the microalga, Scenedesmus quadricauda were studied by flow cytometry, monitoring multiple endpoints of cell density, esterase activity, membrane integrity, reactive oxygen species and chlorophyll fluorescence. Toxicity was clearly in evidence, and although increased esterase activity indicated hormesis during initial exposure to [C4mim][Cl], inhibition of both esterase activity and chlorophyll fluorescence became apparent after 3 days. Cell density was also decreased by culturing with [C4mim][Cl], but this effect was clearly concentration-dependent and only became significant during the second half of the experiment. In contrast, [C4mim][Cl] had only a modest effect on reactive oxygen species (ROS) and caused little damage to cell membranes.

  15. Field assisted hot pressing of sintering Inconel 718 MIM samples

    Science.gov (United States)

    Dugauguez, Olivier; Torralba, Jose Manuel; Barriere, Thierry; Gelin, Jean-Claude

    2016-10-01

    In this investigation on samples obtained by Metal Injection Molding (MIM), the conventional way of sintering in a furnace will be compared to Field Assisted Hot pressing (FAHP) sintering. The difficulty of this method is to be able to control the shrinkage of the sample and so its shape. It has yet not been investigated with a super alloy powder and so, the effects of a high sintering rate. By accelerating the sintering kinetics, the thermal behavior may be modified. Hence, the behavior of the Inconel 718 sintered by FAHP has been investigated. The sintered samples were all injected from a feedstock composed of a fine particle Inconel powder and a binder principally composed of Cellulose Acetate Butyrate CAB and Poly-Ethylene Glycol PEG. The effects of the two methods on the microstructure and the mechanical properties are then compared. There was no difference in distribution of pores between the conventional sintering and the FAHP sintering but a finer grain size showed better hardness.

  16. An enzyme derivatized polydimethylsiloxane (PDMS) membrane for use in membrane introduction mass spectrometry (MIMS).

    Science.gov (United States)

    Creba, A Skye; Weissfloch, Alexandra N E; Krogh, Erik T; Gill, Chris G

    2007-06-01

    Membrane introduction mass spectrometry (MIMS) provides direct measurement of volatile and semivolatile analytes in condensed and gas-phase samples without sample preparation steps. Although MIMS has numerous advantages that include direct, on-line, real-time analysis with low detection limits, current applications of MIMS are predominantly limited to volatile and semivolatile analytes that permeate hydrophobic membranes (e.g., polydimethylsiloxane; PDMS). We report the first enzyme modified PDMS membrane for use with MIMS. This was achieved by immobilizing Candida rugosa lipase directly onto the surface of oxidized PDMS. These surface immobilized enzymes catalyze ester hydrolysis, releasing an alcohol product at the membrane interface that is readily detected. We have successfully used an enzyme modified membrane for the analysis and quantification of low-volatility and hydrophilic esters. We report the quantification of several carboxylic acid esters in dilute aqueous solutions, including a phthalate monoester carboxylate that is not readily detected by conventional MIMS. This new interface demonstrates the potential for extending the range and versatility of MIMS.

  17. Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT-MIM interaction.

    Science.gov (United States)

    Osako, Yohei; Maemoto, Yuki; Tanaka, Ryohei; Suzuki, Hironori; Shibata, Hideki; Maki, Masatoshi

    2010-11-01

    Calpain 7, a mammalian ortholog of yeast Cpl1/Rim13 and fungal PalB, is an atypical calpain that lacks a penta-EF-hand domain. Previously, we reported that a region containing a tandem repeat of microtubule-interacting and transport (MIT) domains in calpain 7 interacts with a subset of endosomal sorting complex required for transport (ESCRT)-III-related proteins, suggesting involvement of calpain 7 in the ESCRT system. Although yeast and fungal calpains are thought to be involved in alkaline adaptation via limited proteolysis of specific transcription factors, proteolytic activity of calpain 7 has not been demonstrated yet. In this study, we investigated the interaction between calpain 7 and a newly reported ESCRT-III family member, increased sodium tolerance-1 (IST1), which possesses two different types of MIT-interacting motifs (MIM1 and MIM2). We found that glutathione-S-transferase (GST)-fused tandem MIT domains of calpain 7 (calpain 7MIT) pulled down FLAG-tagged IST1 expressed in HEK293T cells. Coimmunoprecipitation assays with various deletion or point mutants of epitope-tagged calpain 7 and IST1 revealed that both repetitive MIT domains and MIMs are required for efficient interaction. Direct MIT-MIM binding was confirmed by a pulldown experiment with GST-fused IST1 MIM and purified recombinant calpain 7MIT. Furthermore, we found that the GST-MIM protein enhances the autolysis of purified Strep-tagged monomeric green fluorescent protein (mGFP)-fused calpain 7 (mGFP-calpain 7-Strep). The autolysis was almost completely abolished by 10 mmN-ethylmaleimide but only partially inhibited by 1 mm leupeptin or E-64. The putative catalytic Cys290-substituted mutant (mGFP-calpain 7(C290S)-Strep) showed no autolytic activity. These results demonstrate for the first time that human calpain 7 is proteolytically active, and imply that calpain 7 is activated in the ESCRT system. © 2010 The Authors Journal compilation © 2010 FEBS.

  18. The idiosyncrasies of (BBIM-alkane)DB30C10 MIMs

    Science.gov (United States)

    Ghosh, Sabari; Chaudhuri, Tandrima; Padmanaban, E.; Mukhopadhyay, Chhanda

    2015-10-01

    In this present study we explore the mechanically interlocked molecules (MIMs) resulting from the combination of the BBIM(bis-benzimidazolium)-alkane systems with DB30C10 (Dibenzo-30-crown-10) in solvent acetonitrile. The (BBIM-alkane)DB30C10 systems chosen for the study are (BBIM)DB30C10, (BBIM-methane)DB30C10, (BBIM-ethane)DB30C10, (BBIM-propane)DB30C10 and (BBIM-butane)DB30C10. 1H NMR, 2D-NMR (COSY and NOESY), Monte Carlo calculations and HRMS have been done on the studied assemblies. Even though (BBIM)DB30C10 and (BBIM-methane)DB30C10 form normal threaded structures, in (BBIM-ethane)DB30C10, (BBIM-propane)DB30C10 and (BBIM-butane)DB30C10 systems the respective axles are cradled inside the crown ether. That is, the axles BBIM-ethane, BBIM-propane and BBIM-butane are cradled inside the boat-like cavity of DB30C10.

  19. Magnesium Powder Injection Molding (MIM) of Orthopedic Implants for Biomedical Applications

    Science.gov (United States)

    Wolff, M.; Schaper, J. G.; Suckert, M. R.; Dahms, M.; Ebel, T.; Willumeit-Römer, R.; Klassen, T.

    2016-04-01

    Metal injection molding (MIM) has a high potential for the economic near-net-shape mass production of small-sized and complex-shaped parts. The motivation for launching Mg into the MIM processing chain for manufacturing biodegradable medical implants is related to its compatibility with human bone and its degradation in a non-toxic matter. It has been recognized that the load-bearing capacity of MIM Mg parts is superior to that of biodegradable polymeric components. However, the choice of appropriate polymeric binder components and alloying elements enabling defect-free injection molding and sintering is a major challenge for the use of MIM Mg parts. This study considered the full processing chain for MIM of Mg-Ca alloys to achieve ultimate tensile strength of up to 141 MPa with tensile yield strength of 73 MPa, elongation at fracture Af of 7% and a Young's modulus of 38 GPa. To achieve these mechanical properties, a thermal debinding study was performed to determine optimal furnace and atmosphere conditions, sintering temperature, heating rates, sintering time and pressure.

  20. Continuous system modeling

    Science.gov (United States)

    Cellier, Francois E.

    1991-01-01

    A comprehensive and systematic introduction is presented for the concepts associated with 'modeling', involving the transition from a physical system down to an abstract description of that system in the form of a set of differential and/or difference equations, and basing its treatment of modeling on the mathematics of dynamical systems. Attention is given to the principles of passive electrical circuit modeling, planar mechanical systems modeling, hierarchical modular modeling of continuous systems, and bond-graph modeling. Also discussed are modeling in equilibrium thermodynamics, population dynamics, and system dynamics, inductive reasoning, artificial neural networks, and automated model synthesis.

  1. Fluids and Materials Science Studies Utilizing the Microgravity-vibration Isolation Mount (MIM)

    Science.gov (United States)

    Herring, Rodney; Tryggvason, Bjarni; Duval, Walter

    1998-01-01

    Canada's Microgravity Sciences Program (MSP) is the smallest program of the ISS partners and so can participate in only a few, highly focused projects in order to make a scientific and technological impact. One focused project involves determining the effect of accelerations (g-jitter) on scientific measurements in a microgravity environment utilizing the Microgravity-vibration Isolation Mount (MIM). Many experiments share the common characteristic of having a fluid stage in their process. The quality of the experimental measurements have been expected to be affected by g-jitters which has lead the ISS program to include specifications to limit the level of acceleration allowed on a subset of experimental racks. From finite element analysis (FEM), the ISS structure will not be able to meet the acceleration specifications. Therefore, isolation systems are necessary. Fluid science results and materials science results show significant sensitivity to g-jitter. The work done to date should be viewed only as a first look at the issue of g-jitter sensitivity. The work should continue with high priority such that the international science community and the ISS program can address the requirement and settle on an agreed to overall approach as soon as possible.

  2. Detection of immunolabels with multi-isotope imaging mass spectrometry (MIMS).

    Science.gov (United States)

    Thiery-Lavenant, G; Guillermier, C; Wang, M; Lechene, C

    2014-11-01

    We have developed a method that combines the use of stable isotopes, MIMS and antibody. We began with using well-established antibodies, anti-actin and anti-synaptophysin, in mouse intestinal cells. We extended the method to an immunogold assay to specifically localize Ribeye, a major protein component of retina synaptic ribbons, or to localize a synaptic vesicle-containing protein, synaptophysin. Both are localized in presynaptic nerve terminal of photoreceptors cells in retina. Our results show that by MIMS analysis of the Au signal we can directly identify antibodies tagged with non amplified 1.4 nm gold nanoparticles. They also demonstrate that the gold nanoparticle-tagged antibodies do not dilute the (15)N/(14)N signal used for measuring protein turnover. Thus we can simultaneously and directly use MIMS to measure protein turnover and to identify cell type or specific protein.

  3. The Use of MIMS-MS-MS in field locations as an on-line quantitative environmental monitoring technique for trace contaminants in air and water.

    Science.gov (United States)

    Etzkorn, J M; Davey, N G; Thompson, A J; Creba, A S; Leblanc, C W; Simpson, C D; Krogh, E T; Gill, C G

    2009-01-01

    Membrane introduction mass spectrometry (MIMS) is emerging as an important technique for on-line, real-time environmental monitoring. Because MIMS interfaces are simple and robust, they are ideally suited for operation in MS instrumentation used for in-field applications. We report the use of an on-line permeation tube to continuously infuse an isotopically labeled internal standard for continuous quantitative determinations in atmospheric and aqueous samples without the need for off-line calibration. This approach also provides important information on the operational performance of the analytical system during multi-day deployments. We report measured signal stability during on-line deployments in air and water of 7% based on variation of the internal standard response and have used this technique to quantify BTEX (benzene, toluene, ethylbenzenes, and xylenes), pinenes, naphthalene and 2-methoxyphenol (guaiacol) in urban air plumes at parts-per-billion by volume levels. Presented are several recent applications of MIMS-MS-MS for on-line environmental monitoring in atmospheric and aqueous environmental samples demonstrating laboratory, remote and mobile deployments. We also present the use of a thermally assisted MIMS interface for the direct measurement of polyaromatic hydrocarbons, alkylphenols, and other SVOCs in the low ppb range in aqueous environmental samples and discuss improvements in both the sensitivity and response times for selected SVOCs. The work presented in this paper represents significant improvements in field deployable mass spectrometric techniques, which can be applied to direct on-site analytical measurements of VOC and SVOCs in environmental samples.

  4. Molal Enthalpy of Solution of Ionic Liquid [C2mim][GaCl4

    Institute of Scientific and Technical Information of China (English)

    GUAN,Wei; LIU,Li; WANG,Caixia; YANG,Jiazhen

    2009-01-01

    An ionic liquid (IL),[C2mim][GaCl4](l-ethyl-3-methylimidazolium chlorogallate),was prepared by directly mixing 1-ethyl-3-methylimidazolium chloride ([C2mim][Cl]) and anhydrous GaCI3 with a molar ratio of 1/1 under dry argon.The molal enthalpies of solution,△sHm,of [C2mim][GaCl4],were measured over a molality range of about 0.008-0.1 mol·kg 1 by a solution reaction isoperibol calorimeter at 298.15 K.Considering the hydrolization of anion [GaCl4]- in dissolution process of the IL,a new method of determining the standard molal enthalpy of solution,△sH(⊙)m,was put forward on the basis of Pitzer's mixed electrolyte solution theory so that △sH(⊙)m = -132kJ·mol-1 and the sum of Pitzer's parameters;4β(0)GaCl + 4β(0)[C2mim].Cl + ΦGa,[C2mim]= -0.1373076,β(1)LGa,Cl + β(1)L[C2mim].C=0.3484209 were obtained.In terms of thermodynamic cycle and Glasser's theory of lattice energy for IL,the dissociation enthalpy of [GaCl4]-(g),△Hdis([GaCl4]-)≈5855 kJ·mol-1,that is enthalpy change for the reaction:[GaCl4]-(g)→Ga3+(g) +4Cl- (g),was estimated.

  5. Characterization of a condensed-phase membrane introduction mass spectrometry (CP-MIMS) interface using a methanol acceptor phase coupled with electrospray ionization for the continuous on-line quantitation of polar, low-volatility analytes at trace levels in complex aqueous samples.

    Science.gov (United States)

    Duncan, K D; McCauley, E P B; Krogh, E T; Gill, C G

    2011-05-15

    We report the development and application of a capillary hollow fibre membrane interface using methanol as an acceptor phase to deliver target analytes to an electrospray ionization source and a triple quadrupole mass spectrometer. Superior fluid handling systems lead to greater signal stability and membrane integrity for the continuous on-line monitoring of polar and charged analytes in complex aqueous samples with detection limits in the parts-per-trillion to parts-per-billion range. The system can be operated in either a continuous flow or a stopped acceptor flow mode - the latter giving rise to greater sensitivity. We report detection limits, enrichment factors and signal response times for selected analytes with polydimethylsiloxane and Nafion® polymer membrane interfaces. In addition, we demonstrate the use of this interface to detect pharmaceuticals and other contaminants in natural water and artificial urine. The improved sensitivity and analytical response times of our CP-MIMS system make it possible to continuously monitor dynamic chemical systems with temporal resolutions on the order of minutes. Presented is a comparison of the performance of CP-MIMS versus direct infusion electrospray ionization, demonstrating the potential advantages over direct infusion for trace analyte measurements in complex, high ionic strength samples. Furthermore, by continuously flowing a reaction mixture in a closed loop over the interface, we demonstrate the use of the system as an in situ reaction-monitoring platform for the chlorination of a model organic compound in aqueous solution. Copyright © 2011 John Wiley & Sons, Ltd.

  6. Improvement of magnetic properties of Fe-50mass%Ni in MIM process; MIM process ni okeru Fe-50mass%Ni no jiki tokusei kaizen

    Energy Technology Data Exchange (ETDEWEB)

    Miura, H. [Kumamoto University, Kumamoto (Japan). Faculty of Engineering; Fujita, S. [Kumamoto University, Kumamoto (Japan); Fujita, M.; Ninomiya, R. [Mitsuikinzoku Co. Ltd., Tokyo (Japan)

    2000-12-15

    Metal injection molding (MIM) process is hoped to be one of processing for required to more complicated parts of magnetic components. In this study, the effect of different types of powders (prealloyed and mixed elemental powders) on the magnetic properties of permalloy (Fe-50mass%Ni) through the MIM technique was investigated. Approximately 94% of theoretical density was obtained by using the prealloyed powder, and the retained carbon and oxygen contents were controlled to be low. On the other hand, 96% of theoretical density was obtained by using the mixed elemental powder, but the magnetic properties were inferior to that of prealloyed powder's because of high retained oxygen content. By using the carbonyl Fe powder with high carbon, the retained oxygen and carbon content could be controlled to be low, resulting in the improved magnetic properties. (author)

  7. The contributions to drift of positive and negative thermoelements in type K MIMS thermocouples

    Science.gov (United States)

    Scervini, M.; Rae, C.

    2013-09-01

    As part of the European project HEATTOP a study on drift of MIMS type K thermocouples above 1000°C has been undertaken: in particular the investigation focused on type K thermoelements of Rescal composition. The approach of this study is based on separating the contributions of each thermoelement to the drift which allows a deeper level of understanding of the contributions of different metallurgical modifications for each thermoelement. At temperature above 1000°C contamination of the thermoelements from the sheath becomes an important factor. The negative thermoelement is particularly prone to drift in MIMS configurations.

  8. On the leakage problem of MIM capacitors due to improper etching of titanium nitride

    NARCIS (Netherlands)

    Groenland, A.W.; Wolters, R.A.M.; Kovalgin, A.Y.; Schmitz, J.

    2010-01-01

    In this work, Metal-insulator-metal (MIM) capacitor structures are fabricated in a technology using TiN as electrode material. The electrical characterization revealed devices with small and large leakage currents. Scanning Electron Microscopy (SEM) inspection showed a correlation between high leaka

  9. Usability and User Satisfaction of Multimedia Instructional Message (MIM) for Packet Tracer Simulation

    Science.gov (United States)

    Elias, Mohd Syahrizad; Mohamad Ali, Ahmad Zamzuri

    2016-01-01

    Simulation-aided learning has capability in improving student's learning performance. However, the positive effect of simulation-aided learning still being discussed, which at times has not played the purported role expected. To address these problems, Multimedia Instructional Message (MIM) appeared to be an essential supporting tool in ensuring…

  10. Minimally Invasive Molecular Staging (MIMS) RT-PCR Breast Cancer Study

    Science.gov (United States)

    2007-03-31

    31-03-2007 Final Report 19990426 - 20061231 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Minimally Invasive Molecular Staging (MIMS) N00014-99-1-0784 RT...carcinoma micrometastases in axillary lymph nodes by means of reverse-transcriptase Polymerase chain reaction: comparison between mucl mRNA and keratin-19

  11. Modeling of all-optical even and odd parity generator circuits using metal-insulator-metal plasmonic waveguides

    Science.gov (United States)

    Singh, Lokendra; Bedi, Amna; Kumar, Santosh

    2017-01-01

    Plasmonic metal-insulator-metal (MIM) waveguides sustain excellent property of confining the surface plasmons up to a deep subwavelength scale. In this paper, linear and S-shaped MIM waveguides are cascaded together to design the model of Mach-Zehnder interferometer (MZI). Nonlinear material has been used for switching of light across its output ports. The structures of even and odd parity generators are projected by cascading the MZIs. Parity generator and checker circuit are used for error correction and detection in an optical communication system. Study and analysis of proposed designs are carried out by using the MATLAB simulation and finite-differencetime-domain (FDTD) method.

  12. Extraction of Am(III) using novel solvent systems containing a tripodal diglycolamide ligand in room temperature ionic liquids: a 'green' approach for radioactive waste processing

    NARCIS (Netherlands)

    Sengupta, A; Mohapatra, P.K.; Iqbal, M.; Verboom, Willem; Huskens, Jurriaan; Godbole, S.V.

    2012-01-01

    Extraction of Am3+ from acidic feed solutions was investigated using novel solvent systems containing a tripodal diglycolamide (T-DGA) in three room temperature ionic liquids (RTIL), viz. [C4mim][NTf2], [C6mim][NTf2] and [C8mim][NTf2]. Compared to the results obtained with N,N,N′,N′-tetra-n-octyl

  13. Effect of C8mimPF6 on miniemulsion polymerization for application in new latex coating products.

    Science.gov (United States)

    Hu, Binjie; Kong, Yiyang; Zheng, Rongmeihui; Dong, Jie; Choy, Kwang-Leong; Zhao, Huanhuan

    2016-08-15

    C8mimPF6, as a type of room temperature ionic liquid (RTIL) with non-volatility and a low melting point, may replace conventional coalescing agents in latex coatings, thus preventing volatile organic compound (VOC) emissions caused by coalescing agents. In this study, systematic investigations on the effect of various factors including initiator type, initiator concentration, temperature and C8mimPF6 concentration on the conversion of latex and droplet/particle size of a miniemulsion during polymerization have been conducted. The presence of C8mimPF6 has shown to have a marked effect on the reaction rate. Such an effect strongly depends on the type of initiator being used. For polymerization initiated by 2,2-azobis (isobutyronitrile) (AIBN), C8mimPF6 had a promoting effect on the reaction rate at low concentrations, but this effect might be reversed upon certain C8mimPF6 concentrations, e.g. 10 wt%. While initiated by H2O2/Vc, this promoting effect faded even at low C8mimPF6 concentrations. The different limiting factors, which determine the reaction rate with different types of initiator, may contribute to the results. For reactions initiated by hydrophobic AIBN, the reaction was dominated by kinetics. The presence of C8mimPF6 may cause an enhanced chain propagation rate and reduced chain termination rate, which may further contribute to the increase in reaction rate at lower concentrations of C8mimPF6. With hydrophilic H2O2/Vc, the resistance for the transfer of radicals into a droplet/particle might be increased significantly with increasing C8mimPF6 concentration due to a tighter interfacial structure at lower concentrations of C8mimPF6. Thus, such transfer of radicals may become a limiting step whilst the presence of C8mimPF6 increases the transfer resistance on radicals resulting in a decrease in reaction rate. The reaction temperature, which is related to the decomposition temperature of the initiator being used, was another factor affecting the conversion

  14. Modelling Railway Interlocking Systems

    DEFF Research Database (Denmark)

    Lindegaard, Morten Peter; Viuf, P.; Haxthausen, Anne Elisabeth

    2000-01-01

    In this report we present a model of interlocking systems, and describe how the model may be validated by simulation. Station topologies are modelled by graphs in which the nodes denote track segments, and the edges denote connectivity for train traÆc. Points and signals are modelled by annotatio...

  15. Exploring Possibilities for Transforming Established Subscription-based Scientific Journals into Open Access Journals. Present Situation, Transformation Criteria, and Exemplary Implementation within Trans-O-MIM.

    Science.gov (United States)

    Haux, Reinhold; Kuballa, Stefanie; Schulze, Mareike; Böhm, Claudia; Gefeller, Olaf; Haaf, Jan; Henning, Peter; Mielke, Corinna; Niggemann, Florian; Schürg, Andrea; Bergemann, Dieter

    2016-12-07

    Based on today's information and communication technologies the open access paradigm has become an important approach for adequately communicating new scientific knowledge. Summarizing the present situation for journal transformation. Presenting criteria for adequate transformation as well as a specific approach for it. Describing our exemplary implementation of such a journal transformation. Studying the respective literature as well as discussing this topic in various discussion groups and meetings (primarily of editors and publishers, but also of authors and readers), with long term experience as editors and /or publishers of scientific publications as prerequisite. There is a clear will, particularly of political and funding organizations, towards open access publishing. In spite of this, there is still a large amount of scientific knowledge, being communicated through subscription-based journals. For successfully transforming such journals into open access, sixteen criteria for a goal-oriented, stepwise, sustainable, and fair transformation are suggested. The Tandem Model as transformation approach is introduced. Our exemplary implementation is done in the Trans-O-MIM project. It is exploring strategies, models and evaluation metrics for journal transformation. As instance the journal Methods of Information in Medicine will apply the Tandem Model from 2017 onwards. Within Trans-O-MIM we will reach at least nine of the sixteen criteria for adequate transformation. It was positive to implement Trans-O-MIM as international research project. After first steps for transforming Methods have successfully been made, challenges will remain, among others, in identifying appropriate incentives for open access publishing in order to support its transformation.

  16. Application of solventing-out process on the synthesis of ionic liquid[ C5mim ] [ OAc ]%溶析结晶法在离子液体[ C5mim][OAc]合成中的应用

    Institute of Scientific and Technical Information of China (English)

    付桂红; 李龙; 马晓雪; 佟静; 关伟

    2011-01-01

    研究了用溶析结晶法辅助合成一种新型的碱性离子液体:1-甲基-3-戊基咪唑醋酸盐([C5mim] [OAc]),并通过1HNMR进行了表征.合成[c5mim][ OAc]所需中间体溴代1-甲基-3-戊基咪唑[C5mim][ Br],因其凝固点很低给重结晶纯化带来了难度.基于这一点,本文提出了用二次去离子水作为析出剂进行离子液体[ C5mim][ Br]重结晶提纯.通过多次水平实验,得到了提纯中析出剂加入量的最加配比,并就提纯后产物的回收率进行了讨论.%A new ionic liquid [C5mim] [Oac] ( l-methyl-3-amylimidazolium acetate) was synthesized by solventing-out process and the sample was confirmed by 'HNMR. Anion exchange resin was used to synthesize [C,mim] [Oac]. Because the difficult of purification of [ C,mim] [ Br] by recrys-tallization due to low freezing point in its synthesis process of intermediate [C3mim] [ Br ] ( 1-methyl-3-amylimidazolium bromine) the secondary deionized water as precipitation agent of recrystallization about purification of ionic liquid [Cjinim] [ Br] was used. The most precipitation agent addition ratio in the purification were obtained, and the recovery ratio of product was discussed in the after purification.

  17. Therapeutic effects of CO2 laser therapy of linear nevus sebaceous in the course of the Schimmelpenning-Feuerstein-Mims syndrome.

    Science.gov (United States)

    Kiedrowicz, Magdalena; Kacalak-Rzepka, Anna; Królicki, Andrzej; Maleszka, Romuald; Bielecka-Grzela, Stanisława

    2013-10-01

    The Schimmelpenning-Feuerstein-Mims (SFM) syndrome is a rare phakomatosis which comprises a nevus sebaceous of Jadassohn, seizures and developmental delay associated with a wide spectrum of extracutaneous abnormalities including neurological, skeletal, ocular, cardiovascular and urogenital defects. We are presenting a case of an 18-year-old patient with systemic features of the SFM syndrome and an extensive linear nevus sebaceous partially removed with a carbon dioxide (CO2) laser. The treatment options of skin lesions in patients with SFM are discussed.

  18. Development of feedstock of tungsten-nickel-iron- polyformaldehyde for MIM technology

    Science.gov (United States)

    Kostin, D. V.; Parkhomenko, A. V.; Amosov, A. P.; Samboruk, A. R.; Chemashkin, A. V.

    2016-11-01

    The article presents the results of the research and development of technology and formulation of the feedstock from domestic metal powders and polymers to fabricate complexshaped components from heavy alloy of VNZh 7-3 brand (90 wt. % tungsten - 7% nickel - 3% iron) by Metal Injection Molding (MIM technology). The metal part of the feedstock is composed of powders of tungsten, nickel and iron, and the polymer part is composed of polyformaldehyde with the addition of low-density polyethylene and beeswax. The modes of mixing the components and the influence of the composition of the feedstock on the melt flow rate and the homogeneity of the feedstock were investigated. The optimal formulation of the feedstock was determined. Microstructure, density and hardness of control samples fabricated by MIM technology from the developed feedstock, correspond to, and in some respects are superior to the samples of VNZh 7-3 alloy fabricated by technology of traditional powder metallurgy.

  19. 绿色荧光蛋白探针标记的 MIM-I-BAR 基因构建和表达%Construction and expression of GFP conjugated MIM-I-BAR

    Institute of Scientific and Technical Information of China (English)

    曹萌; 常维维; 许阳; 方琳静; 刘袁; 顾宁

    2015-01-01

    为制备可视化的转移消失蛋白(MIM)的 I-BAR 结构域重组体,克隆了顺联绿色荧光蛋白(GFP)探针编码序列的 MIM-I-BAR 基因.在6xHis 标签原核表达质粒上成功构建了 DNA 序列.同时,实现了未标记荧光探针基因的 MIM-I-BAR 质粒的构建以作实验对照.成功转染至 BL21(DE3)大肠杆菌细胞后,GFP 偶联的 MIM-I-BAR (MIM-I-BAR-GFP)蛋白表现出很强的可视荧光,该表达产物可方便的通过目测、荧光显微镜、免疫印迹和紫外可见分光光度计等多种手段进行检测.此外,在考察不同条件下的蛋白表达效率过程中发现,带有 GFP 探针的 MIM-I-BAR 重组蛋白在温度为10℃时产率最高,而并非37℃.这一特征与非荧光标记的 MIM-I-BAR 明显不同.研究证实该最佳表达温度条件适用于重组蛋白产品中量制备.所开发的带有荧光探针的 MIM-I-BAR 蛋白产品及其制备工艺在科学研究、生物医学应用以及药物开发过程中均有较高的应用价值.%To achieve a visible inverse Bin-amphiphysin-Rvs (I-BAR)domain recombinant of missing in metastasis (MIM) protein,the green fluorescent protein (GFP)encoding gene was cloned at the terminal of MIM-I-BAR as a probe.The DNA was successfully constructed on a 6xHis-tagged prokaryotic expression plasmid.The non-GFP labeled MIM-I-BAR encoding plasmid was also constructed as a control. Being successfully transformed into BL21 (DE3 )cells,the GFP-conjugated MIM-I-BAR (MIM-I-BAR-GFP ) exhibits strong visible fluorescence,and the expression product can be easily detected by visual inspection, a fluorescence microscope, Western blot or ultraviolet and visible spectrophotometer. Moreover, examination of expression efficiency under various culture conditions revealed that the MIM-I-BAR-GFP gene has a high protein yield at 10 ℃,but not at the culture temperature of 37 ℃.This property is much different from that of the non

  20. Inelastic and Reactive Scattering Dynamics of Hyperthermal Oxygen Atoms on Ionic Liquid Surfaces: [emim][NTf2] and [C12mim][NTf2

    Science.gov (United States)

    Wu, Bohan; Zhang, Jianming; Minton, Timothy K.; McKendrick, Kenneth G.; Slattery, John M.; Yockel, Scott; Schatz, George C.

    2011-05-01

    Collisions of hyperthermal oxygen atoms, with an average translational energy of 520 kJ mol-1, on continuously refreshed ionic liquids, 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl) imide ([emim][NTf2]) and 1-dodecyl-3-methylimidazolium bis(trifluoromethylsulfonyl) imide ([C12mim][NTf2]), were studied with the use of a beam-surface scattering technique. Time-of-flight and angular distributions of inelastically scattered O and reactively scattered OH and H2O were collected for various angles of incidence with the use of a rotatable mass spectrometer detector. For both O and OH, two distinct scattering processes were identified, which can be empirically categorized as thermal and non-thermal. Non-thermal scattering is more probable for both O and OH products. The observation of OH confirms that at least some reactive sites, presumably alkyl groups, must be exposed at the surface. The ionic liquid with the longer alkyl chain, [C12mim][NTf2], is substantially more reactive than the liquid with the shorter alkyl chain, [emim][NTf2], and proportionately much more so than would be predicted simply from stoichiometry based on the number of abstractable hydrogen atoms. Molecular dynamics models of these surfaces shed light on this change in reactivity. The scattering behavior of O is distinctly different from that of OH. However, no such differences between inelastic and reactive scattering dynamics have been seen in previous work on pure hydrocarbon liquids, in particular the benchmark, partially branched hydrocarbon, squalane (C30H62). The comparison between inelastic and reactive scattering dynamics indicates that inelastic scattering from the ionic liquid surfaces takes place predominantly at non-reactive sites that are effectively stiffer than the reactive alkyl chains, with a higher proportion of collisions sampling such sites for [emim][NTf2] than for [C12mim][NTf2].

  1. A miniature condensed-phase membrane introduction mass spectrometry (CP-MIMS) probe for direct and on-line measurements of pharmaceuticals and contaminants in small, complex samples.

    Science.gov (United States)

    Duncan, Kyle D; Willis, Megan D; Krogh, Erik T; Gill, Christopher G

    2013-06-15

    High-throughput, automated analytical measurements are desirable in many analytical scenarios, as are rapid sample pre-screening techniques to identify 'positive' samples for subsequent measurements using more time-consuming conventional methodologies (e.g., liquid chromatography/mass spectrometry (LC/MS)). A miniature condensed-phase membrane introduction mass spectrometry (CP-MIMS) probe for the direct and continuous, on-line measurement of pharmaceuticals and environmental contaminants in small, complex samples is presented. A miniature polydimethylsiloxane hollow fibre membrane (PDMS-HFM) probe is coupled with an electrospray ionization (ESI) triple quadrupole mass spectrometer. Analytes are transported from the probe to the ESI source by a methanol acceptor phase. The probe can be autosampler mounted and directly inserted in small samples (≥400 μL) allowing continuous and simultaneous pptr-ppb level detection of target analytes (chlorophenols, triclosan, gemfibrozil, nonylphenol) in complex samples (artificial urine, beer, natural water, waste water, plant tissue). The probe has been characterized and optimized for acceptor phase flow rate, sample mixing and probe washing. Signal response times, detection limits and calibration data are given for selected ion monitoring (SIM) and tandem mass spectrometry (MS/MS) measurements of target analytes at trace levels. Comparisons with flow cell type CP-MIMS systems are given. Analyte depletion effects are evaluated for small samples (≥400 μL). On-line measurements in small volumes of complex samples, temporally resolved reaction monitoring and in situ/in vivo demonstrations are presented. The miniature CP-MIMS probe developed was successfully used for the direct, on-line detection of target analytes in small volumes (40 mL to 400 μL) of complex samples at pptr to low ppb levels. The probe can be readily automated as well as deployed for in situ/in vivo monitoring, including reaction monitoring, small sample

  2. Selected System Models

    Science.gov (United States)

    Schmidt-Eisenlohr, F.; Puñal, O.; Klagges, K.; Kirsche, M.

    Apart from the general issue of modeling the channel, the PHY and the MAC of wireless networks, there are specific modeling assumptions that are considered for different systems. In this chapter we consider three specific wireless standards and highlight modeling options for them. These are IEEE 802.11 (as example for wireless local area networks), IEEE 802.16 (as example for wireless metropolitan networks) and IEEE 802.15 (as example for body area networks). Each section on these three systems discusses also at the end a set of model implementations that are available today.

  3. Structural Fine-Tuning of MIT-Interacting Motif 2 (MIM2) and Allosteric Regulation of ESCRT-III by Vps4 in Yeast.

    Science.gov (United States)

    Kojima, Rieko; Obita, Takayuki; Onoue, Kousuke; Mizuguchi, Mineyuki

    2016-06-05

    The endosomal sorting complex required for transport (ESCRT) facilitates roles in membrane remodeling, such as multivesicular body biogenesis, enveloped virus budding and cell division. In yeast, Vps4 plays a crucial role in intraluminal vesicle formation by disassembling ESCRT proteins. Vps4 is recruited by ESCRT-III proteins to the endosomal membrane through the interaction between the microtubule interacting and trafficking (MIT) domain of Vps4 and the C-terminal MIT-interacting motif (MIM) of ESCRT-III proteins. Here, we have determined the crystal structure of Vps4-MIT in a complex with Vps20, a member of ESCRT-III, and revealed that Vps20 adopts a unique MIM2 conformation. Based on structural comparisons with other known MIM2s, we have refined the consensus sequence of MIM2. We have shown that another ESCRT-III protein, Ist1, binds to Vps4-MIT via its C-terminal MIM1 with higher affinity than Vps2, but lacks MIM2 by surface plasmon resonance. Surprisingly, the Ist1 MIM1 competed with the MIM2 of Vfa1, a regulator of Vps4, for binding to Vps4-MIT, even though these MIMs bind in non-overlapping sites on the MIT. These findings provide insight into the allosteric recognition of MIMs of ESCRT-III by Vps4 and also the regulation of ESCRT machinery at the last step of membrane remodeling. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Modeling cellular systems

    CERN Document Server

    Matthäus, Franziska; Pahle, Jürgen

    2017-01-01

    This contributed volume comprises research articles and reviews on topics connected to the mathematical modeling of cellular systems. These contributions cover signaling pathways, stochastic effects, cell motility and mechanics, pattern formation processes, as well as multi-scale approaches. All authors attended the workshop on "Modeling Cellular Systems" which took place in Heidelberg in October 2014. The target audience primarily comprises researchers and experts in the field, but the book may also be beneficial for graduate students.

  5. Multiscale Cloud System Modeling

    Science.gov (United States)

    Tao, Wei-Kuo; Moncrieff, Mitchell W.

    2009-01-01

    The central theme of this paper is to describe how cloud system resolving models (CRMs) of grid spacing approximately 1 km have been applied to various important problems in atmospheric science across a wide range of spatial and temporal scales and how these applications relate to other modeling approaches. A long-standing problem concerns the representation of organized precipitating convective cloud systems in weather and climate models. Since CRMs resolve the mesoscale to large scales of motion (i.e., 10 km to global) they explicitly address the cloud system problem. By explicitly representing organized convection, CRMs bypass restrictive assumptions associated with convective parameterization such as the scale gap between cumulus and large-scale motion. Dynamical models provide insight into the physical mechanisms involved with scale interaction and convective organization. Multiscale CRMs simulate convective cloud systems in computational domains up to global and have been applied in place of contemporary convective parameterizations in global models. Multiscale CRMs pose a new challenge for model validation, which is met in an integrated approach involving CRMs, operational prediction systems, observational measurements, and dynamical models in a new international project: the Year of Tropical Convection, which has an emphasis on organized tropical convection and its global effects.

  6. Design, Fabrication and Characterization of MIM Diodes and Frequency Selective Thermal Emitters for Solar Energy Harvesting and Detection Devices

    Science.gov (United States)

    Sharma, Saumya

    could be achieved in this case. These long chain polymeric molecules exhibit a two-dimensional molecular assembly thereby reducing the tunneling distance between the metal electrodes on either side of the insulating layer. Rectification ratios as high as 450:1 at +/-200mV were obtained for an MIM diode configuration of Ni-LB films of Arachidic Acid films-(Au/Pd). The bandwidth of the incident radiation that can be used by this rectenna assembly is limited to 9.5% of 30THz or +/-1.5THz from the center frequency based on the antenna designs which were proposed for this research. This bandwidth constraint has led to research in the field of frequency selective emitters capable of providing a narrowband emission around 30THz. Several grating structures were fabricated in the form of Ni-Si periodic arrays, in a cleanroom environment using photolithography, sputtering and deep reactive ion etching. These frequency selective samples were characterized with the help of focusing optics, monochromators and HgCdTe detectors. The results obtained from the emission spectra were utilized to calibrate a simulation model with Computer Simulation Technology (CST) which uses numerous robust solving techniques, such as the finite element method, in order to obtain the optical parameters for the model. Thereafter, a thorough analysis of the different dimensional and material parameters was performed, to understand their dependence on the emissivity of the selective emitter. Further research on the frequency selectivity of the periodic nano-disk or nano-hole array led to the temperature dependence of the simulated spectra, because the material parameters, such as refractive index or drude model collision frequency, vary with temperature. Thus, the design of frequency selective absorbers/emitters was found to be significantly affected with temperature range of operation of these structures.

  7. Dynamic Systems Modeling

    Directory of Open Access Journals (Sweden)

    Sorin Dan ŞANDOR

    2003-01-01

    Full Text Available System Dynamics was introduced by Jay W. Forrester in the 1960s. Since then the methodology was adopted in many areas of natural or social sciences. This article tries to present briefly how this methodology works, both as Systems Thinking and as Modelling with Vensim computer software.

  8. Rheological assessment of titanium MIM feedstocks [Conference paper

    CSIR Research Space (South Africa)

    Benson, JM

    2010-10-01

    Full Text Available � ������������������������������������������������������������������������������ � Page 348� � 2. Experimental Procedure A binder system, based on EVA and a wax, was used to prepare feedstock with varying powder loadings. In all three cases the total mass of the binder components were kept constant, while only the mass... ivit ric s In nfe ic �� IC eri e cu ess ap e se e ent y r mo fr ill ed e me ati an ibe n t u t ies an iti ren hte ��� A J al xc rre th art tot re tal ial e-m uld om in bi mo nt ve d m s t he...

  9. Low-Temperature Drift in MIMS Base-Metal Thermocouples

    Science.gov (United States)

    Webster, E. S.

    2014-04-01

    Inhomogeneities are known to develop within thermoelements exposed to elevated temperatures, resulting in temperature measurement errors. While the Seebeck coefficient drift in base-metal thermocouples due to aging at temperatures over has been extensively investigated, there have been very few investigations into possible Seebeck changes at lower temperatures. Despite warnings about possible effects, most practitioners assume changes in homogeneity are either not significant or not able to develop at temperatures less than . This study reports on measurements of inhomogeneities in base-metal thermocouples arising from heat treatment at temperatures in the region of . Thermoelectric scans of thermocouples were carried out following exposure of a range of mineral-insulated metal-sheathed base-metal thermocouples, from two large manufacturers, of Types E, J, K, N, and T, to either a linear-gradient furnace within the range of to or uniform temperature zones of , , and . The experiments reveal noticeable drift in all base-metal types for temperatures as low as and exposure times as short as 1 h. The most sensitive thermoelement alloys appear to be Constantan, Alumel, and Nicrosil. It is concluded that the common working assumption that base-metal thermocouples suffer no thermally induced changes in the Seebeck coefficient below is false. This observation has significant implications for many high-stability monitoring and control systems reliant on base-metal thermocouples that operate in the range of to . Additionally, thermoelectric scanning of base-metal thermocouples should be carried out at temperatures well below to avoid erasure of strain effects or imprinting of new thermal signatures.

  10. The Extent of Denitrification in Long Island Groundwater using MIMS

    Science.gov (United States)

    Young, C.; Hanson, G. N.; Kroeger, K. D.

    2009-12-01

    Long Island drinking water is provided by a sole source aquifer with nitrate levels in some North Shore communities approaching or exceeding the drinking water standard of 10 mgL-1. Previous workers, using mass balance approaches, suggested that the primary source of nitrogen is sewage effluent and observed a 50% deficit of nitrate in Long Island’s groundwater system. We analyzed dissolved N2/Ar ratios in groundwater from wells to determine if groundwater denitrification is the cause of the nitrogen deficit at two locations where septic tanks are used for sewage treatment and the effluent leaches to the groundwater; a suburban community on the north shore of Long Island (Northport, NY) and parkland on a barrier island at the south shore of Long Island (Watch Hill, Fire Island National Seashore). In Northport we found 0 to 20 % of the nitrate in groundwater denitrified with excess N-NO3- concentrations ranging from 0 to 1.5 mgL-1. These samples had concentrations high in dissolved oxygen (DO), 6 to 11 mgL-1, and low in dissolved organic carbon (DOC), 0.4 to 2.8 mgL-1. At Watch Hill nitrogen is primarily retained as ammonium or dissolved organic nitrogen. Where nitrate is formed, we found up to 99% denitrification. Excess N-NO3- ranged from 0 to 8 mgL-1 with concentrations low in DO, 0.3 to 3.4 mgL-1, and high in DOC, 5.3 to 18.4 mgL-1. The vadose zone in the Northport area has an average thickness of 10-100 feet whereas at Watch Hill it is 1 - 2 feet thick. We hypothesize that the vadose zone thickness affects the extent of denitrification by controlling the amount of DOC and DO that reaches the groundwater. A thick vadose zone allows for more extensive interaction of infiltrating sewage effluent with atmospheric oxygen in the vadose zone which oxidizes DOC. In Northport groundwater has high DO, low DOC and essentially no denitrification leaving 2 to 11 mgL-1 N-NO3- remaining. At the Watch Hill site a thin vadose zone below the sewage leach field provides

  11. Modeling Sustainable Food Systems

    Science.gov (United States)

    Allen, Thomas; Prosperi, Paolo

    2016-05-01

    The processes underlying environmental, economic, and social unsustainability derive in part from the food system. Building sustainable food systems has become a predominating endeavor aiming to redirect our food systems and policies towards better-adjusted goals and improved societal welfare. Food systems are complex social-ecological systems involving multiple interactions between human and natural components. Policy needs to encourage public perception of humanity and nature as interdependent and interacting. The systemic nature of these interdependencies and interactions calls for systems approaches and integrated assessment tools. Identifying and modeling the intrinsic properties of the food system that will ensure its essential outcomes are maintained or enhanced over time and across generations, will help organizations and governmental institutions to track progress towards sustainability, and set policies that encourage positive transformations. This paper proposes a conceptual model that articulates crucial vulnerability and resilience factors to global environmental and socio-economic changes, postulating specific food and nutrition security issues as priority outcomes of food systems. By acknowledging the systemic nature of sustainability, this approach allows consideration of causal factor dynamics. In a stepwise approach, a logical application is schematized for three Mediterranean countries, namely Spain, France, and Italy.

  12. Modeling Complex Systems

    CERN Document Server

    Boccara, Nino

    2010-01-01

    Modeling Complex Systems, 2nd Edition, explores the process of modeling complex systems, providing examples from such diverse fields as ecology, epidemiology, sociology, seismology, and economics. It illustrates how models of complex systems are built and provides indispensable mathematical tools for studying their dynamics. This vital introductory text is useful for advanced undergraduate students in various scientific disciplines, and serves as an important reference book for graduate students and young researchers. This enhanced second edition includes: . -recent research results and bibliographic references -extra footnotes which provide biographical information on cited scientists who have made significant contributions to the field -new and improved worked-out examples to aid a student’s comprehension of the content -exercises to challenge the reader and complement the material Nino Boccara is also the author of Essentials of Mathematica: With Applications to Mathematics and Physics (Springer, 2007).

  13. Distributed generation systems model

    Energy Technology Data Exchange (ETDEWEB)

    Barklund, C.R.

    1994-12-31

    A slide presentation is given on a distributed generation systems model developed at the Idaho National Engineering Laboratory, and its application to a situation within the Idaho Power Company`s service territory. The objectives of the work were to develop a screening model for distributed generation alternatives, to develop a better understanding of distributed generation as a utility resource, and to further INEL`s understanding of utility concerns in implementing technological change.

  14. A narrativa dos afetos no documentário O Samba que mora em mim

    Directory of Open Access Journals (Sweden)

    Maria Angela Pavan

    2013-08-01

    Full Text Available This article intents to understand the affectionate look of theBrazilian filmmaker Geórgia Guerra-Peixe. We can see that look in her documentarycalled O samba que mora em mim, winner of the jury special award of the São PauloFilm Festival [Mostra de Cinema de São Paulo], in 2010. For this study we interviewedGeórgia, collected information published in the press when the documentary was release,in february 2011, and we make a film analysis.

  15. Standards and the INSDC: Submission of MIGS, MIMS, MIENS (GSC8 Meeting)

    Energy Technology Data Exchange (ETDEWEB)

    Mizrachi, Ilene [NCBI

    2009-09-09

    The Genomic Standards Consortium was formed in September 2005. It is an international, open-membership working body which promotes standardization in the description of genomes and the exchange and integration of genomic data. The 2009 meeting was an activity of a five-year funding "Research Coordination Network" from the National Science Foundation and was organized held at the DOE Joint Genome Institute with organizational support provided by the JGI and by the University of California - San Diego. Ilene Mizrachi of the NCBI talks about submission of MIGS/MIMS/MIENS information at the Genomic Standards Consortium's 8th meeting at the DOE JGI in Walnut Creek, Calif. on Sept. 9, 2009.

  16. Analysis and Geometry : MIMS-GGTM, in Honour of Mohammed Salah Baouendi

    CERN Document Server

    Kacimi, Aziz; Kallel, Sadok; Mir, Nordine

    2015-01-01

    This book includes selected papers presented at the MIMS (Mediterranean Institute for the Mathematical Sciences) - GGTM (Geometry and Topology Grouping for the Maghreb) conference, held in memory of Mohammed Salah Baouendi, a most renowned figure in the field of several complex variables, who passed away in 2011. All research articles were written by leading experts, some of whom are prize winners in the fields of complex geometry, algebraic geometry and analysis. The book offers a valuable resource for all researchers interested in recent developments in analysis and geometry.

  17. Brain stem cell division and maintenance studied using multi-isotope imaging mass spectrometry (MIMS).

    Science.gov (United States)

    Enikolopov, G; Guillermier, C; Wang, M; Trakimas, L; Steinhauser, M; Lechene, C

    2014-11-01

    New neurons are continuously produced from neural stem cells in specific regions of the adult brain of animals and humans. In the hippocampus, a region crucial for cognitive function, neurogenesis responds to a multitude of extrinsic stimuli; emerging evidence indicates that it may be important for behavior, pathophysiology, brain repair, and response to drugs. We have developed an approach to identify and quantify the cellular targets of pro- and anti-neurogenic stimuli, based on reporter transgenic mouse lines in which neural stem and progenitor cells or their progeny are marked by fluorescent proteins. Here, we demonstrate the feasibility of using MIMS for studying adult neurogenesis.

  18. Modeling the earth system

    Energy Technology Data Exchange (ETDEWEB)

    Ojima, D. [ed.

    1992-12-31

    The 1990 Global Change Institute (GCI) on Earth System Modeling is the third of a series organized by the Office for Interdisciplinary Earth Studies to look in depth at particular issues critical to developing a better understanding of the earth system. The 1990 GCI on Earth System Modeling was organized around three themes: defining critical gaps in the knowledge of the earth system, developing simplified working models, and validating comprehensive system models. This book is divided into three sections that reflect these themes. Each section begins with a set of background papers offering a brief tutorial on the subject, followed by working group reports developed during the institute. These reports summarize the joint ideas and recommendations of the participants and bring to bear the interdisciplinary perspective that imbued the institute. Since the conclusion of the 1990 Global Change Institute, research programs, nationally and internationally, have moved forward to implement a number of the recommendations made at the institute, and many of the participants have maintained collegial interactions to develop research projects addressing the needs identified during the two weeks in Snowmass.

  19. Development of InGaAsSb Based Monolithic Interconnected Modules (MIMs)

    Science.gov (United States)

    Palmisiano, M. N.; Biefeld, R. M.; Cederberg, J. G.; Hafich, M. J.; Peake, G. M.

    2003-01-01

    The quaternary Sb-based materials are attractive for use in TPV devices due to the versatility associated with being able to grow InGaAsSb and AlGaAsSb material with a wide range of band gaps lattice matched to a GaSb substrate. Photodiodes (0.60 eV) consisting of an InGaAsSb p/n junction grown on GaSb were fabricated and characterized to establish baseline electrical performance of the material. In order to fabricate monolithic interconnected modules (MIMs) from these photodiodes using a conductive GaSb substrate, an electrical isolation layer must be added between the active layers and the substrate. For this purpose, AlGaAsSb cell isolation diodes (CIDs) were developed and characterized with respect to their ability to block current in reverse bias. These structures were combined in the first MIM structures grown and fabricated from Sb-based materials on GaSb substrates.

  20. Development of Metal Plate with Internal Structure Utilizing the Metal Injection Molding (MIM Process

    Directory of Open Access Journals (Sweden)

    Kwangho Shin

    2013-12-01

    Full Text Available In this study, we focus on making a double-sided metal plate with an internal structure, such as honeycomb. The stainless steel powder was used in the metal injection molding (MIM process. The preliminary studies were carried out for the measurement of the viscosity of the stainless steel feedstock and for the prediction of the filling behavior through Computer Aided Engineering (CAE simulation. PE (high density polyethylene (HDPE and low density polyethylene (LDPE and polypropylene (PP resins were used to make the sacrificed insert with a honeycomb structure using a plastic injection molding process. Additionally, these sacrificed insert parts were inserted in the metal injection mold, and the metal injection molding process was carried out to build a green part with rectangular shape. Subsequently, debinding and sintering processes were adopted to remove the sacrificed polymer insert. The insert had a suitable rigidity that was able to endure the filling pressure. The core shift analysis was conducted to predict the deformation of the insert part. The 17-4PH feedstock with a low melting temperature was applied. The glass transition temperature of the sacrificed polymer insert would be of a high grade, and this insert should be maintained during the MIM process. Through these processes, a square metal plate with a honeycomb structure was made.

  1. Binding of Substrates to the Central Pore of the Vps4 ATPase Is Autoinhibited by the Microtubule Interacting and Trafficking (MIT) Domain and Activated by MIT Interacting Motifs (MIMs)*

    Science.gov (United States)

    Han, Han; Monroe, Nicole; Votteler, Jörg; Shakya, Binita; Sundquist, Wesley I.; Hill, Christopher P.

    2015-01-01

    The endosomal sorting complexes required for transport (ESCRT) pathway drives reverse topology membrane fission events within multiple cellular pathways, including cytokinesis, multivesicular body biogenesis, repair of the plasma membrane, nuclear membrane vesicle formation, and HIV budding. The AAA ATPase Vps4 is recruited to membrane necks shortly before fission, where it catalyzes disassembly of the ESCRT-III lattice. The N-terminal Vps4 microtubule-interacting and trafficking (MIT) domains initially bind the C-terminal MIT-interacting motifs (MIMs) of ESCRT-III subunits, but it is unclear how the enzyme then remodels these substrates in response to ATP hydrolysis. Here, we report quantitative binding studies that demonstrate that residues from helix 5 of the Vps2p subunit of ESCRT-III bind to the central pore of an asymmetric Vps4p hexamer in a manner that is dependent upon the presence of flexible nucleotide analogs that can mimic multiple states in the ATP hydrolysis cycle. We also find that substrate engagement is autoinhibited by the Vps4p MIT domain and that this inhibition is relieved by binding of either Type 1 or Type 2 MIM elements, which bind the Vps4p MIT domain through different interfaces. These observations support the model that Vps4 substrates are initially recruited by an MIM-MIT interaction that activates the Vps4 central pore to engage substrates and generate force, thereby triggering ESCRT-III disassembly. PMID:25833946

  2. Binding of Substrates to the Central Pore of the Vps4 ATPase Is Autoinhibited by the Microtubule Interacting and Trafficking (MIT) Domain and Activated by MIT Interacting Motifs (MIMs).

    Science.gov (United States)

    Han, Han; Monroe, Nicole; Votteler, Jörg; Shakya, Binita; Sundquist, Wesley I; Hill, Christopher P

    2015-05-22

    The endosomal sorting complexes required for transport (ESCRT) pathway drives reverse topology membrane fission events within multiple cellular pathways, including cytokinesis, multivesicular body biogenesis, repair of the plasma membrane, nuclear membrane vesicle formation, and HIV budding. The AAA ATPase Vps4 is recruited to membrane necks shortly before fission, where it catalyzes disassembly of the ESCRT-III lattice. The N-terminal Vps4 microtubule-interacting and trafficking (MIT) domains initially bind the C-terminal MIT-interacting motifs (MIMs) of ESCRT-III subunits, but it is unclear how the enzyme then remodels these substrates in response to ATP hydrolysis. Here, we report quantitative binding studies that demonstrate that residues from helix 5 of the Vps2p subunit of ESCRT-III bind to the central pore of an asymmetric Vps4p hexamer in a manner that is dependent upon the presence of flexible nucleotide analogs that can mimic multiple states in the ATP hydrolysis cycle. We also find that substrate engagement is autoinhibited by the Vps4p MIT domain and that this inhibition is relieved by binding of either Type 1 or Type 2 MIM elements, which bind the Vps4p MIT domain through different interfaces. These observations support the model that Vps4 substrates are initially recruited by an MIM-MIT interaction that activates the Vps4 central pore to engage substrates and generate force, thereby triggering ESCRT-III disassembly. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  3. Mechanical Systems, Classical Models

    CERN Document Server

    Teodorescu, Petre P

    2009-01-01

    This third volume completes the Work Mechanical Systems, Classical Models. The first two volumes dealt with particle dynamics and with discrete and continuous mechanical systems. The present volume studies analytical mechanics. Topics like Lagrangian and Hamiltonian mechanics, the Hamilton-Jacobi method, and a study of systems with separate variables are thoroughly discussed. Also included are variational principles and canonical transformations, integral invariants and exterior differential calculus, and particular attention is given to non-holonomic mechanical systems. The author explains in detail all important aspects of the science of mechanics, regarded as a natural science, and shows how they are useful in understanding important natural phenomena and solving problems of interest in applied and engineering sciences. Professor Teodorescu has spent more than fifty years as a Professor of Mechanics at the University of Bucharest and this book relies on the extensive literature on the subject as well as th...

  4. NEP systems model

    Science.gov (United States)

    George, Jeffrey A.

    A new nuclear electric propulsion (NEP) systems analysis code is discussed. The new code is modular and consists of a driver code and various subsystem models. The code models five different subsystems: (1) reactor/shield; (2) power conversion; (3) heat rejection; (4) power management and distribution (PMAD); and (5) thrusters. The code optimizes for the following design criteria: minimum mass; minimum radiator area; and low mass/low area. The code also optimizes the following parameters: separation distance; temperature ratio; pressure ratio; and transmission frequency. The discussion is presented in vugraph form.

  5. The ESO-MIM Star Trek: A broadbased public oriented short interactive exhibition for an introduction to contemporary astrophysics

    Science.gov (United States)

    Marco, O.; Miranda, F.

    2005-12-01

    In the course of the European Southern Observatory (ESO) Public Relations work in Chile, we have created a permanent exhibition of astronomy for a broad section of the public in the Museo Interactivo Mirador-MIM (Interactive Museum of science, Chile), a collaboration between ESO and MIM. This Museum is mostly directed towards schoolchildren (7-14 years old), with adult visits at weekends. It is funded by public money and is unique in Chile. We decided to present the most recent questions relative to astronomy, based on pictures taken mostly at ESO observatories, and to skip the basics of astronomy that are taught at school.

  6. National Energy Modeling System

    Energy Technology Data Exchange (ETDEWEB)

    Skinner, C.W. (Energy Information Administration, Washington, DC (United States))

    1993-01-01

    The Energy Information Administration is developing a new National Energy Modeling System to provide annual forecasts of energy supply, demand, and prices on a regional basis in the United States and, to a limited extent, in the rest of the world. The design for the system was based on a requirements analysis, a comparison of requirements with existing modeling capabilities, and a series of widely circulated issue papers defining the choices and tradeoffs for 13 key design decisions. An initial prototpye of the new NEMS was implemented in late 1992, with a more complete, operational version in 1993. NEMS is expected to provide EIA and other users with a greatly enhanced ability to illustrate quickly and effectively the effects of a wide range of energy policy proposals.

  7. Modeling Novo Nordisk Production Systems

    DEFF Research Database (Denmark)

    Miller, Thomas Dedenroth

    1997-01-01

    This report describes attributes of models and systems, and how models can be used for description of production systems. There are special attention on the 'Theory of Domains'.......This report describes attributes of models and systems, and how models can be used for description of production systems. There are special attention on the 'Theory of Domains'....

  8. System of systems modeling and analysis.

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, James E.; Anderson, Dennis James; Longsine, Dennis E. (Intera, Inc., Austin, TX); Shirah, Donald N.

    2005-01-01

    This report documents the results of an LDRD program entitled 'System of Systems Modeling and Analysis' that was conducted during FY 2003 and FY 2004. Systems that themselves consist of multiple systems (referred to here as System of Systems or SoS) introduce a level of complexity to systems performance analysis and optimization that is not readily addressable by existing capabilities. The objective of the 'System of Systems Modeling and Analysis' project was to develop an integrated modeling and simulation environment that addresses the complex SoS modeling and analysis needs. The approach to meeting this objective involved two key efforts. First, a static analysis approach, called state modeling, has been developed that is useful for analyzing the average performance of systems over defined use conditions. The state modeling capability supports analysis and optimization of multiple systems and multiple performance measures or measures of effectiveness. The second effort involves time simulation which represents every system in the simulation using an encapsulated state model (State Model Object or SMO). The time simulation can analyze any number of systems including cross-platform dependencies and a detailed treatment of the logistics required to support the systems in a defined mission.

  9. Toxicity of [C_8mim]PF_6 to aquatic organisms%离子液体[C_8mim]PF_6对水生生物的毒性作用

    Institute of Scientific and Technical Information of China (English)

    牧辉; 彭新晶; 戴宁; 陈继; 张凤君

    2009-01-01

    Three standard test methods for evaluating the toxicity of chemicals to aquatic organisms were applied to assess the toxic effects of l-octyl-3-methylimidazolium PF_6([C_8mim]PF_6)on the three aquatic organisms: Chlorella vulgaris, Daphnia magna and zebra fish. Growth and chlorophyll a content of C. vulgaris were inhibited in the experimental content of [C_8mim]PF_6, the inhibiting effect increased significantly with increasing concentrations, and the toxic effects on chlorophyll a content were stronger than that of growth. The C. vulgaris cell even would be lethal in the higher concentration group (200mg/L). The toxic effects of [C_8mim] PF_6 was high-toxic to Daphnia magna, while was low-toxic to zebra fish, and the 48h LC_(50) and 96h LC_(50) was 4.47mg/L and 126.08mg/L, respectively. EC50/LC50 changed regularly with the test time. Maybe the two main reasons leading to the potential threat to the aquatic organisms were the affinity of [C_8mim]PF_6 with algae and lipophilic property itself.%运用评价化学品对水生生物毒性的标准试验方法,探讨离子液体1-辛基-3-甲基-咪唑六氟磷酸盐([C_8mim]PF_6)对普通小球藻、大型蚤和斑马鱼的毒性影响.结果表明,[C_8mim]PF_6在实验浓度下,对普通小球藻的生长和叶绿素a的产生均有抑制作用,浓度越高抑制作用越明显,且对叶绿素a含量的影响更为显著.高浓度组(200mg/L)可致死部分小球藻细胞;[C_8mim]PF_6对大型蚤的48h LC50为4.47mg/L,属于高毒性;[C_8mim]PF_6对斑马鱼的96h LC50为126.08mg/L,属于低毒性.[C_8mim]PF_6对这3种水生生物的抑制率/致死率(EC50/LC50)随时间呈规律性变化.[C_8mim]PF_6与藻类的亲和性及其亲脂特性可能是其对水生生物存在潜在毒性的2个主要原因.

  10. Discordance for Schimmelpenning-Feuerstein-Mims syndrome in monochorionic twins supports the concept of a postzygotic mutation.

    Science.gov (United States)

    Rijntjes-Jacobs, Esther G J; Lopriore, Enrico; Steggerda, Sylke J; Kant, Sarina G; Walther, Frans J

    2010-11-01

    The Schimmelpenning-Feuerstein-Mims (SFM) syndrome comprises a craniofacial nevus sebaceus, seizures, developmental delay, ocular and skeletal abnormalities. It is a sporadic condition and hypothesized to result from mosaicism involving a lethal autosomal dominant gene. We report a second occurrence of discordant monozygotic (MZ) twins with severe SFM, supporting the concept of a postzygotic mutation. © 2010 Wiley-Liss, Inc.

  11. Jacob y el otro: una lectura desde el deseo mimético

    OpenAIRE

    Navascués, J. (Javier) de

    2009-01-01

    El artículo propone el análisis del cuento de Juan Carlos Onetti “Jacob y el otro” a partir de la teoría antropológica de René Girard. Así, el universo de Onetti aparece configurado por distintos aspectos del llamado “deseo mimético”. Este concepto determina que las relaciones de deseo entre un sujeto y un objeto no se establecen de forma directa, sino a través de un juego triangular formado por un sujeto, un modelo y un objeto. Al objeto se llega a través del modelo, a quien Girard denomina ...

  12. A case of sebaceous nevus sindrome (Schimmelpen-ning-Feuerstein-Mims syndrome).

    Science.gov (United States)

    Rubegni, P; Poggiali, S; Sbano, P; Nami, N; Hayek, J; Motolese, P A; Fimiani, M

    2009-10-01

    The sebaceous nevus syndrome (SNS) is characterized by the presence of a sebaceous nevus and extracutaneous abnormalities, usually involving organs derived from the neuroectoderm. The authors report the case of a 22 year-old patient with a systematized sebaceous nevus on the forehead and scalp and a history of developmental delay and severe seizure disorders. The father of the patient also indicated prior surgery to correct an ocular coloboma and prior removal of a squamous cell epithelioma of the tongue. Firstly described by Gustav Schimmelpenning in 1957, SNS, also known as 'Schimmelpenning-Feuerstein-Mims syndrome', is one of the six different types of epidermal nevus syndromes. In patients with SNS the risk of developing neoplasms is higher than that of the general population. The particularity of our case lies in the late diagnosis. The authors believe that early diagnosis and awareness of the potential presence of neoplasms are important for those involved in the care of patients with SNS.

  13. A novel design for monolithic interconnected modules (MIMs) for thermophotovoltaic (TPV) power conversion

    Energy Technology Data Exchange (ETDEWEB)

    Ward, J.S.; Duda, A.; Wanlass, M.W. [National Renewable Energy Lab., Golden, CO (United States)] [and others

    1997-06-01

    The design for the fabrication of Monolithic Interconnected Modules (MIMs) for thermophotovoltaic (TPV) power conversion described in this paper utilizes a novel, interdigitated contacting scheme that increases the flexibility in the size of the component cells and hence the output current and voltage of the module. This flexibility is gained at the expense of only minimally increased grid obscuration. Because the design uses the grid fingers of the component cells as the interconnect structure, the area of the device used for this purpose becomes negligible. In this paper the authors report on the specifics of the design as well as issues related to the fabrication of the modules. Preliminary performance data for representative modules also are offered.

  14. Strong coupling effects between a meta-atom and MIM nanocavity

    Directory of Open Access Journals (Sweden)

    San Chen

    2012-09-01

    Full Text Available In this paper, we investigate the strong coupling effects between a meta-atom and a metal-insulator-metal (MIM nanocavity. By changing the meta-atom sizes, we achieve the meta-atomic electric dipole, quadrupole or multipole interaction with the plasmonic nanocavity, in which characteristic anticrossing behaviors demonstrate the occurrence of the strong coupling. The various interactions present obviously different splitting values and behaviors of dependence on the meta-atomic position. The largest Rabi-type splittings, about 360.0 meV and 306.1 meV, have been obtained for electric dipole and quadrupole interaction, respectively. We attribute the large splitting to the highly-confined cavity mode and the large transition dipole of the meta-atom. Also the Rabi-type oscillation in time domain is given.

  15. IR detection and energy harvesting using antenna coupled MIM tunnel diodes

    Science.gov (United States)

    Yesilkoy, Filiz

    The infrared (IR) spectrum lies between the microwave and optical frequency ranges, which are well suited for communication and energy harvesting purposes, respectively. The long wavelength IR (LWIR) spectrum, corresponding to wavelengths from 8microm to 15microm, includes the thermal radiation emitted by objects at room temperature and the Earth's terrestrial radiation. Therefore, LWIR detectors are very appealing for thermal imaging purposes. Thermal detectors developed so far either demand cryogenic operation for fast detection, or they rely on the accumulation of thermal energy in their mass and subsequent measurable changes in material properties. Therefore, they are relatively slow. Quantum detectors allow for tunable and instantaneous detection but are expensive and require complex processes for fabrication. Bolometer detectors are simple and cheap but do not allow for tunability or for rapid detection. Harvesting the LWIR radiation energy sourced by the Earth's heating/cooling cycle is very important for the development of mobile energy resources. While speed is not as significant an issue here, conversion efficiency is an eminent problem for cheap, large area energy transduction. This dissertation addresses the development of tunable, fast, and low cost wave detectors that can operate at room temperature and, when produced in large array format, can harvest Earth's terrestrial radiation energy. This dissertation demonstrates the design, fabrication and testing of Antenna Coupled Metal-Insulator-Metal (ACMIM) tunnel diodes optimized for 10microm wavelength radiation detection. ACMIM tunnel diodes operate as electromagnetic wave detectors: the incident radiation is coupled by an antenna and converted into a 30 terahertz signal that is rectified by a fast tunneling MIM diode. For efficient IR radiation coupling, the antenna geometry and its critical dimensions are studied using a commercial finite-element based multi-physics simulation tool, and the half

  16. Quantitative imaging of inositol distribution in yeast using multi-isotope imaging mass spectrometry (MIMS).

    Science.gov (United States)

    Saiardi, A; Guillermier, C; Loss, O; Poczatek, J C; Lechene, C

    2014-11-01

    Despite the widely recognized importance of the several species of inositol polyphosphates in cell biology, inositol has not been successfully imaged and quantified inside cells using traditional spectrophotometry. Multi-isotope imaging mass spectrometry (MIMS) technology, however, has facilitated direct imaging and measurement of cellular inositol. After pulsing cells with inositol labeled with the stable isotope Carbon-13 ((13)C), the label was detected in subcellular volumes by MIMS. The tridimensional localization of (13)C within the cell illustrated cellular distribution and local accumulation of inositol. In parallel, we performed control experiments with (13)C-Glucose to compare a different (13)C distribution pattern. Because many functions recently attributed to inositol polyphosphates are localized in the nucleus, we analyzed its relative nuclear concentration. We engineered yeast with human thymidine permease and viral thymidine kinase, then fed them with (15)N-thymidine. This permitted direct analysis of the nuclear DNA through the detection of the (15)N isotopic signal. We found practically no co-localization between inositol signal ((13)C-isotope) and nuclear signal ((15)N-isotope). The (13)C-tag (inositol) accumulation was highest at the plasma membrane and in cytoplasmic domains. In time-course labeling experiments performed with wild type yeast (WT) or modified yeast unable to synthesize inositol from glucose (ino1Δ), the half-time of labeled inositol accumulation was ~1 hour in WT and longer in ino1Δ. These studies should serve as a template to study metabolism and physiological role of inositol using genetically modified yeasts.

  17. Submitting MIGS, MIMS, MIENS Information to EMBL and Standards and the Sequencing Pipelines of the Gordon and Betty Moore Foundation (GSC8 Meeting)

    Energy Technology Data Exchange (ETDEWEB)

    Vaughan, Bob [EMBL; Kaye, Jon [Gordon and Betty Moore Foundation

    2009-09-09

    The Genomic Standards Consortium was formed in September 2005. It is an international, open-membership working body which promotes standardization in the description of genomes and the exchange and integration of genomic data. The 2009 meeting was an activity of a five-year funding "Research Coordination Network" from the National Science Foundation and was organized held at the DOE Joint Genome Institute with organizational support provided by the JGI and by the University of California - San Diego. Bob Vaughan of EMBL on submitting MIGS/MIMS/MIENS information to EMBL-EBI's system, followed by a brief talk from Jon Kaye of the Gordon and Betty Moore Foundation on standards and the foundation's sequencing pipelines at the Genomic Standards Consortium's 8th meeting at the DOE JGI in Walnut Creek, Calif. on Sept. 9, 2009

  18. Biogenesis of the mitochondrial TOM complex: Mim1 promotes insertion and assembly of signal-anchored receptors.

    Science.gov (United States)

    Becker, Thomas; Pfannschmidt, Sylvia; Guiard, Bernard; Stojanovski, Diana; Milenkovic, Dusanka; Kutik, Stephan; Pfanner, Nikolaus; Meisinger, Chris; Wiedemann, Nils

    2008-01-04

    The translocase of the outer membrane (TOM complex) is the central entry gate for nuclear-encoded mitochondrial precursor proteins. All Tom proteins are also encoded by nuclear genes and synthesized as precursors in the cytosol. The channel-forming beta-barrel protein Tom40 is targeted to mitochondria via Tom receptors and inserted into the outer membrane by the sorting and assembly machinery (SAM complex). A further outer membrane protein, Mim1, plays a less defined role in assembly of Tom40 into the TOM complex. The three receptors Tom20, Tom22, and Tom70 are anchored in the outer membrane by a single transmembrane alpha-helix, located at the N terminus in the case of Tom20 and Tom70 (signal-anchored) or in the C-terminal portion in the case of Tom22 (tail-anchored). Insertion of the precursor of Tom22 into the outer membrane requires pre-existing Tom receptors while the import pathway of the precursors of Tom20 and Tom70 is only poorly understood. We report that Mim1 is required for efficient membrane insertion and assembly of Tom20 and Tom70, but not Tom22. We show that Mim1 associates with SAM(core) components to a large SAM complex, explaining its role in late steps of the assembly pathway of Tom40. We conclude that Mim1 is not only required for biogenesis of the beta-barrel protein Tom40 but also for membrane insertion and assembly of signal-anchored Tom receptors. Thus, Mim1 plays an important role in the efficient assembly of the mitochondrial TOM complex.

  19. ECO-BIOLOGICAL SYSTEM MODELING

    Directory of Open Access Journals (Sweden)

    T. I. Burak

    2015-01-01

    Full Text Available The methodology for computer modeling of complex eco-biological models is presented in this paper. It is based on system approach of J. Forrester. Developed methodology is universal for complex ecological and biological systems. Modeling algorithm considers specialties of eco-biological systems and shows adequate and accurate results in practice. 

  20. Mathematical System Theory and System Modeling

    OpenAIRE

    1980-01-01

    Choosing models related effectively to the questions to be addressed is a central issue in the craft of systems analysis. Since the mathematical description the analyst chooses constrains the types of issues he candeal with, it is important for these models to be selected so as to yield limitations that are acceptable in view of the questions the systems analysis seeks to answer. In this paper, the author gives an overview of the central issues affecting the question of model choice. To ...

  1. Model Reduction of Hybrid Systems

    DEFF Research Database (Denmark)

    Shaker, Hamid Reza

    systems are derived in this thesis. The results are used for output feedback control of switched nonlinear systems. Model reduction of piecewise affine systems is also studied in this thesis. The proposed method is based on the reduction of linear subsystems inside the polytopes. The methods which......High-Technological solutions of today are characterized by complex dynamical models. A lot of these models have inherent hybrid/switching structure. Hybrid/switched systems are powerful models for distributed embedded systems design where discrete controls are applied to continuous processes...... of hybrid systems, designing controllers and implementations is very high so that the use of these models is limited in applications where the size of the state space is large. To cope with complexity, model reduction is a powerful technique. This thesis presents methods for model reduction and stability...

  2. Modelling on fuzzy control systems

    Institute of Scientific and Technical Information of China (English)

    LI; Hongxing(李洪兴); WANG; Jiayin(王加银); MIAO; Zhihong(苗志宏)

    2002-01-01

    A kind of modelling method for fuzzy control systems is first proposed here, which is calledmodelling method based on fuzzy inference (MMFI). It should be regarded as the third modelling method thatis different from two well-known modelling methods, that is, the first modelling method, mechanism modellingmethod (MMM), and the second modelling method, system identification modelling method (SlMM). Thismethod can, based on the interpolation mechanism on fuzzy logic system, transfer a group of fuzzy inferencerules describing a practice system into a kind of nonlinear differential equation with variable coefficients, calledHX equations, so that the mathematical model of the system can be obtained. This means that we solve thedifficult problem of how to get a model represented as differential equations on a complicated or fuzzy controlsystem.

  3. Energy System Modeling with REopt

    Energy Technology Data Exchange (ETDEWEB)

    Simpkins, Travis; Anderson, Kate; Cutler, Dylan; Olis, Dan; Elgqvist, Emma; DiOrio, Nick; Walker, Andy

    2016-07-15

    This poster details how REopt - NREL's software modeling platform for energy systems integration and optimization - can help to model energy systems. Some benefits of modeling with REopt include optimizing behind the meter storage for cost and resiliency, optimizing lab testing, optimizing dispatch of utility scale storage, and quantifying renewable energy impact on outage survivability.

  4. An effective method for enhancing metal-ions' selectivity of ionic liquid-based extraction system: Adding water-soluble complexing agent.

    Science.gov (United States)

    Sun, Xiao Qi; Peng, Bo; Chen, Ji; Li, De Qian; Luo, Fang

    2008-01-15

    Selective extraction-separation of yttrium(III) from heavy lanthanides into 1-octyl-3-methylimidazolium hexafluorophosphate ([C(8)mim][PF(6)]) containing Cyanex 923 was achieved by adding a water-soluble complexing agent (EDTA) to aqueous phase. The simple and environmentally benign complexing method was proved to be an effective strategy for enhancing the selectivity of [C(n)mim][PF(6)]/[Tf(2)N]-based extraction system without increasing the loss of [C(n)mim](+).

  5. A standard MIGS/MIMS compliant XML Schema: toward the development of the Genomic Contextual Data Markup Language (GCDML).

    Science.gov (United States)

    Kottmann, Renzo; Gray, Tanya; Murphy, Sean; Kagan, Leonid; Kravitz, Saul; Lombardot, Thierry; Field, Dawn; Glöckner, Frank Oliver

    2008-06-01

    The Genomic Contextual Data Markup Language (GCDML) is a core project of the Genomic Standards Consortium (GSC) that implements the "Minimum Information about a Genome Sequence" (MIGS) specification and its extension, the "Minimum Information about a Metagenome Sequence" (MIMS). GCDML is an XML Schema for generating MIGS/MIMS compliant reports for data entry, exchange, and storage. When mature, this sample-centric, strongly-typed schema will provide a diverse set of descriptors for describing the exact origin and processing of a biological sample, from sampling to sequencing, and subsequent analysis. Here we describe the need for such a project, outline design principles required to support the project, and make an open call for participation in defining the future content of GCDML. GCDML is freely available, and can be downloaded, along with documentation, from the GSC Web site (http://gensc.org).

  6. Cerebral manifestations, hemihypertrophy and lymphoedema of one leg in a child with epidermal nevus syndrome (Schimmelpenning-Feuerstein-Mims)

    Energy Technology Data Exchange (ETDEWEB)

    Neumann, Luitgard M.; Kunze, Juergen [Institute of Human Genetics, Charite, Campus Virchow-Klinikum, Augustenburger Platz 1, Humboldt University, 13353 Berlin (Germany); Scheer, Ianina; Stoever, Brigitte [Pediatric Radiology Strahlenklinik und Poliklinik, Charite, Campus Virchow-Klinikum, Humboldt-University, Berlin (Germany)

    2003-09-01

    The report focuses on a rare variant form of epidermal nevus syndrome (ENS) (Schimmelpenning-Feuerstein-Mims syndrome) describing lesions involving the skin, eyes, skeleton, heart and brain in an 11-year-old boy. Despite his evident brain pathology, the boy lacks neurological symptoms and mental retardation. We describe his unusual MRI appearances and radiographic skeletal findings. To our knowledge this is the first report of ENS with lymphoedema occurring together in the same individual. (orig.)

  7. A novel approach of manufacturing Nickel Wicks for loop heat pipes using Metal Injection Moulding (MIM)

    Indian Academy of Sciences (India)

    S K Samanta; Prosenjit Das; A K Lohar; H Roy; S Kumar; A K Chowdhury

    2013-04-01

    Sintered nickel powder is proposed to be used as porous wicks in loop heat pipes used for space applications such as satellites and space crafts. In this work, the manufacturing procedure for tubular wicks through novel Metal Injection Moulding (MIM) route is discussed. Nickel powder, Polypropylene powder and thermoplastic binder are used to produce feedstock for injection moulding. Ideal sintering condition identified as 900° C and 60 minutes. Porosity, pore diameter of the wicks are evaluated by geometric measurements using an electronic weight measuring machine and a micrometer and extrusion flow Porosimeter, respectively. Permeability was calculated according to the Carmen–Kozeny equation. Experimental finding shows that porosity level of 55 vol%, average pore diameter of 2.6 m, permeability of 1.94 × 10−12m2 and roundness of 5% have been achieved in the porous wick. SEM investigation of pore structures shows the presence of large pores which leads to enhanced porosity and interconnected fine pore network responsible for generation of required capillary pumping pressure.

  8. The mental illness microaggressions scale-perpetrator version (MIMS-P): Reliability and validity.

    Science.gov (United States)

    Gonzales, Lauren; Davidoff, Kristin C; DeLuca, Joseph S; Yanos, Philip T

    2015-09-30

    The study objective was to develop a new measure for use in the empirical measurement of microaggression behaviors perpetrated towards persons with mental illness and examine its psychometric properties. Following development of an initial item pool, 505 participants (students at a large college in New York City and community members recruited through Amazon's Mechanical Turk program) completed an online survey including a 20-item measure of microaggression behaviors. Exploratory factor analysis revealed three subscales: Assumption of Inferiority (α=0.81), Patronization (α=0.78), and Fear of Mental Illness (α=0.63). Additional analyses supported convergent validity of the measure with two widely used measures of mental illness stigma. The MIMS-P is the first instrument to measure microaggressions endorsed by perpetrators against a socially marginalized group and demonstrates strong psychometric properties. Inclusion of this scale in future research can help facilitate understanding of perpetrator perspectives and assist with intervention development. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  9. Effect of an anti-depressant on mouse hippocampus protein turnover using MIMS.

    Science.gov (United States)

    Filiou, M D; Moy, J; Wang, M; Guillermier, C; Poczatek, J C; Turck, C; Lechene, C

    2014-11-01

    Although antidepressants have been used in the treatment of affective disorders for over fifty years, the precise mechanism of their action remains unknown. Treatment regimens are based by and large on empirical parameters and characterized by a trial and error scheme. A better understanding of the mechanisms involved in antidepressant drug response is of fundamental importance for the development of new compounds that have a higher success rate and specificity. In order to elucidate the molecular pathways involved in the action of antidepressants, we wish to identify brain areas, cell types, and organelles that are targeted by antidepressant treatment in mice. Multi-isotope Imaging Mass Spectrometry (MIMS) allows a quantitative approach to this analysis, allowing us to delineate antidepressant effect on protein synthesis in the brain at single cell and organelle resolution. In these experiments, we obtained a global analysis of protein turnover in the hippocampus dentate gyrus (DG) and in the Cornu Ammonis (CA) regions, together with a subcellular analysis in the granular cells and others.

  10. Quantifying cell division with deuterated water and multi-isotope imaging mass spectrometry (MIMS).

    Science.gov (United States)

    Steinhauser, Matthew L; Guillermier, Christelle; Wang, Mei; Lechene, Claude P

    2014-11-01

    Cell division is commonly quantified by the administration of nucleotide labels that are incorporated by the nucleotide salvage pathway. A new approach uses precursors of the de novo nucleotide synthesis pathway, such as labeled water or glucose. Because such precursors are not specific for DNA synthesis, studies utilizing this approach have analyzed isolated genomic DNA to exclude nonspecific background labeling. We hypothesized that pulse-chase administration of stable isotope labeled water would result in sufficient nuclear labeling to enable discrimination of recently divided cells by quantitative ion microscopy. We administered deuterated (D)-water and (15)N-thymidine to mice concurrently, guided by the rationale that (15)N-thymidine incorporation would serve as a "gold standard" to identify dividing cells. We show both qualitatively and quantitatively that dividing cells in the small intestine ((15)N-labeled) demonstrate a discernable D-signal in the nucleus not observed in undivided cells ((15)N-unlabled). Correlation with (31)P(-) and (12)C(15)N(-):(12)C(14)N(-) images demonstrate preferential localization of (2)H labeling in regions of the nucleus with high DNA content as expected of labeling being incorporated during DNA synthesis and cell division. These data support the concept that stable isotope tagged precursors of the de novo nucleotide synthesis pathway can be used in concert with NanoSIMS to study cell division in vivo. A major implication of this study then is the possibility of using stable isotope tagged water and MIMS to study human cell turnover.

  11. Sputter deposition of thin film MIM capacitors on LTCC substrates for RF bypass and filtering applications

    Energy Technology Data Exchange (ETDEWEB)

    Murray, Jack [Missouri University of Science and Technology; O' Keefe, Matthew J. [Missouri University of Science and Technology; Wilder, Kristina [Missouri University of Science and Technology; Eatinger, Ryan [Kansas State University; Kuhn, William [Kansas State University; Krueger, Daniel S. [Honeywell Federal Manufacturing & Technologies; Wolf, J. Ambrose [Honeywell Federal Manufacturing & Technologies

    2011-08-31

    Thin film capacitors for RF bypass and filtering applications were sputter deposited onto low temperature co-fired ceramic (LTCC) substrates. The capacitors were configured in a metal-insulator-metal (MIM) design featuring 200 nm thick Al electrodes and a 300 nm thick Al{sub 2}O{sub 3} dielectric layer, with dimensions varied between ~150x150 μm and ~750x750 μm. DC current-voltage measurements (E ≤ 5 MV/cm) coupled with impedance analysis (≤15 MHz) was used to characterize the resulting devices. More than 90% of the devices functioned as capacitors with high DC resistance (>20 MΩ) and low loss (tan δ <0.1). A second set of capacitors were made under the same experimental conditions with device geometries optimized for high frequency (≥200 MHz) applications. These capacitors featured temperature coefficient of capacitance (TCC) values between 500 and 1000 ppm/°C as well as low loss and high self-resonant frequency performance (ESR <0.6 Ohms at self-resonance of 5.7 GHz for 82 pF). Capacitance and loss values were comparable between the capacitor structures of similar areas at the different frequency regimes.

  12. Modeling soft interface dominated systems

    NARCIS (Netherlands)

    Lamorgese, A.; Mauri, R.; Sagis, L.M.C.

    2017-01-01

    The two main continuum frameworks used for modeling the dynamics of soft multiphase systems are the Gibbs dividing surface model, and the diffuse interface model. In the former the interface is modeled as a two dimensional surface, and excess properties such as a surface density, or surface energy

  13. Validation of systems biology models

    NARCIS (Netherlands)

    Hasdemir, D.

    2015-01-01

    The paradigm shift from qualitative to quantitative analysis of biological systems brought a substantial number of modeling approaches to the stage of molecular biology research. These include but certainly are not limited to nonlinear kinetic models, static network models and models obtained by the

  14. Modeling of deterministic chaotic systems

    Energy Technology Data Exchange (ETDEWEB)

    Lai, Y. [Department of Physics and Astronomy and Department of Mathematics, The University of Kansas, Lawrence, Kansas 66045 (United States); Grebogi, C. [Institute for Plasma Research, University of Maryland, College Park, Maryland 20742 (United States); Grebogi, C.; Kurths, J. [Department of Physics and Astrophysics, Universitaet Potsdam, Postfach 601553, D-14415 Potsdam (Germany)

    1999-03-01

    The success of deterministic modeling of a physical system relies on whether the solution of the model would approximate the dynamics of the actual system. When the system is chaotic, situations can arise where periodic orbits embedded in the chaotic set have distinct number of unstable directions and, as a consequence, no model of the system produces reasonably long trajectories that are realized by nature. We argue and present physical examples indicating that, in such a case, though the model is deterministic and low dimensional, statistical quantities can still be reliably computed. {copyright} {ital 1999} {ital The American Physical Society}

  15. Modelling of wastewater systems

    DEFF Research Database (Denmark)

    Bechmann, Henrik

    In this thesis, models of pollution fluxes in the inlet to 2 Danish wastewater treatment plants (WWTPs) as well as of suspended solids (SS) concentrations in the aeration tanks of an alternating WWTP and in the effluent from the aeration tanks are developed. The latter model is furthermore used...

  16. Simulating suppression effects in Pulsed ENDOR, and the 'hole in the middle' of Mims and Davies ENDOR Spectra.

    Science.gov (United States)

    Doan, Peter E; Lees, Nicholas S; Shanmugam, Muralidharan; Hoffman, Brian M

    2010-01-01

    All pulsed ENDOR techniques, and in particular the Mims and Davies sequences, suffer from detectability biases ('blindspots') that are directly correlated to the size of the hyperfine interactions of coupled nuclei. Our efforts at ENDOR 'crystallography' and 'mechanism determination' with these techniques has led our group to refine our simulations of pulsed ENDOR spectra to take into account these biases, and we here describe the process and illustrate it with several examples. We first focus on an issue whose major significance is not widely appreciated, the 'hole in the middle' of pulsed ENDOR spectra caused by the n = 0 suppression hole in Mims ENDOR and by the analogous A→0 suppression in Davies ENDOR (Section I). This section discusses the issue for nuclei with I = ½ and also for (2)H (I = 1), using the treatment of Section II. In Section II we discuss the general treatment of suppression effects for I = 1, illustrating it with a treatment of Mims suppression for (14)N (I = 1) (Section II).

  17. Modelling Epistemic Systems

    CERN Document Server

    Martins, Andre C R

    2012-01-01

    In this Chapter, I will explore the use of modeling in order to understand how Science works. I will discuss the modeling of scientific communities, providing a general, non-comprehensive overview of existing models, with a focus on the use of the tools of Agent-Based Modeling and Opinion Dynamics. A special attention will be paid to models inspired by a Bayesian formalism of Opinion Dynamics. The objective of this exploration is to better understand the effect that different conditions might have on the reliability of the opinions of a scientific community. We will see that, by using artificial worlds as exploring grounds, we can prevent some epistemological problems with the definition of truth and obtain insights on the conditions that might cause the quest for more reliable knowledge to fail.

  18. From Numeric Models to Granular System Modeling

    Directory of Open Access Journals (Sweden)

    Witold Pedrycz

    2015-03-01

    To make this study self-contained, we briefly recall the key concepts of granular computing and demonstrate how this conceptual framework and its algorithmic fundamentals give rise to granular models. We discuss several representative formal setups used in describing and processing information granules including fuzzy sets, rough sets, and interval calculus. Key architectures of models dwell upon relationships among information granules. We demonstrate how information granularity and its optimization can be regarded as an important design asset to be exploited in system modeling and giving rise to granular models. With this regard, an important category of rule-based models along with their granular enrichments is studied in detail.

  19. Pluralistic Modeling of Complex Systems

    CERN Document Server

    Helbing, Dirk

    2010-01-01

    The modeling of complex systems such as ecological or socio-economic systems can be very challenging. Although various modeling approaches exist, they are generally not compatible and mutually consistent, and empirical data often do not allow one to decide what model is the right one, the best one, or most appropriate one. Moreover, as the recent financial and economic crisis shows, relying on a single, idealized model can be very costly. This contribution tries to shed new light on problems that arise when complex systems are modeled. While the arguments can be transferred to many different systems, the related scientific challenges are illustrated for social, economic, and traffic systems. The contribution discusses issues that are sometimes overlooked and tries to overcome some frequent misunderstandings and controversies of the past. At the same time, it is highlighted how some long-standing scientific puzzles may be solved by considering non-linear models of heterogeneous agents with spatio-temporal inte...

  20. Integrated Modeling Systems

    Science.gov (United States)

    1989-01-01

    American Economic Review , 71:1 (March 1981). 181 J.M. Jones and F. Zufryden. "Adding Explanatory Variables to a Consumer Purchase Behavior Model: An...McCall. "An Operational Measure of Liquidity," The American Economic Review , 761 (March 1986). WMSI Working Paper 329. 212 Nelson, R., R. Sarin, and R

  1. Robust Disaster Recovery System Model

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Highly security-critical system should possess features of continuous service. We present a new Robust Disaster Recovery System Model (RDRSM). Through strengthening the ability of safe communications, RDRSM guarantees the secure and reliable command on disaster recovery. Its self-supervision capability can monitor the integrality and security of disaster recovery system itself. By 2D and 3D real-time visible platform provided by GIS, GPS and RS, the model makes the using, management and maintenance of disaster recovery system easier. RDRSM possesses predominant features of security, robustness and controllability. And it can be applied to highly security-critical environments such as E-government and bank. Conducted by RDRSM, an important E-government disaster recovery system has been constructed successfully. The feasibility of this model is verified by practice. We especially emphasize the significance of some components of the model, such as risk assessment, disaster recovery planning, system supervision and robust communication support.

  2. Mechanical Systems, Classical Models

    CERN Document Server

    Teodorescu, Petre P

    2007-01-01

    All phenomena in nature are characterized by motion; this is an essential property of matter, having infinitely many aspects. Motion can be mechanical, physical, chemical or biological, leading to various sciences of nature, mechanics being one of them. Mechanics deals with the objective laws of mechanical motion of bodies, the simplest form of motion. In the study of a science of nature mathematics plays an important role. Mechanics is the first science of nature which was expressed in terms of mathematics by considering various mathematical models, associated to phenomena of the surrounding nature. Thus, its development was influenced by the use of a strong mathematical tool; on the other hand, we must observe that mechanics also influenced the introduction and the development of many mathematical notions. In this respect, the guideline of the present book is precisely the mathematical model of mechanics. A special accent is put on the solving methodology as well as on the mathematical tools used; vectors, ...

  3. Studies of Catalytic Model Systems

    DEFF Research Database (Denmark)

    Holse, Christian

    The overall topic of this thesis is within the field of catalysis, were model systems of different complexity have been studied utilizing a multipurpose Ultra High Vacuum chamber (UHV). The thesis falls in two different parts. First a simple model system in the form of a ruthenium single crystal...... is investigated. Second the development of a complex Cu/ZnO nanoparticle model system is described and gas-induced dynamical changes in the model system is investigated. The ruthenium crystal serves as an extremely simple model for studying CO dissociation which is the rate limiting step of the methanation...... process. The Ru(0 1 54) surface is studied by means of Scanning Tunneling Microscopy (STM), Temperature Programmed Desoprtion (TPD), and Oxygen Titration (OT) experiments. Real space evidence of periodic features on every second monatomic step is observed via STM when the a clean ruthenium surface...

  4. Relocatable Coastal Modeling System

    Science.gov (United States)

    2016-06-07

    These relationships are stored on a variable-resolution grid (illustrated in figure 1b below) with sampling of 1 degree in deep water (and in data...version is referred to as MODAS2.1, which is now operational at NAVO. The NOMADS interface is being replaced by a system-independent, web -based version...inside the user’s web browser plus Perl CGI scripts which ran on a webserver. This permitted the user to run MODAS (and POM and other modules as they are

  5. Solvent Debinding of MIM Parts in a Polystyrene-Palm Oil Based Binder System

    Science.gov (United States)

    Asmawi, R.; Ibrahim, M. H. I.; Amin, A. M.; Mustafa, N.

    2016-11-01

    The influence of the leaching temperatures on the solvent debinding process of SS316L stainless steel alloy compact has been investigated. Solvent debinding process of injection moulded SS316L feedstock was conducted to eliminate palm kernel oil by using n- heptane solution at various temperatures of 40, 50 and 60°C and at different time duration up to 9 hours. The samples were prepared by injection molding a mixture of stainless steel SS316L alloy with waste polystyrene polymer and palm kernel oil at powder loading 60% vol. The weight loss percentages of palm kernel were calculated and the pore structure evolution was analyzed by scanning electron micrograph to observe the pores created after solvent extraction process. Results show that a complete diffusion of the palm kernel molecules out of the compact part best at 60°C within 6 hours of extraction time

  6. Hydronic distribution system computer model

    Energy Technology Data Exchange (ETDEWEB)

    Andrews, J.W.; Strasser, J.J.

    1994-10-01

    A computer model of a hot-water boiler and its associated hydronic thermal distribution loop has been developed at Brookhaven National Laboratory (BNL). It is intended to be incorporated as a submodel in a comprehensive model of residential-scale thermal distribution systems developed at Lawrence Berkeley. This will give the combined model the capability of modeling forced-air and hydronic distribution systems in the same house using the same supporting software. This report describes the development of the BNL hydronics model, initial results and internal consistency checks, and its intended relationship to the LBL model. A method of interacting with the LBL model that does not require physical integration of the two codes is described. This will provide capability now, with reduced up-front cost, as long as the number of runs required is not large.

  7. Data management system performance modeling

    Science.gov (United States)

    Kiser, Larry M.

    1993-01-01

    This paper discusses analytical techniques that have been used to gain a better understanding of the Space Station Freedom's (SSF's) Data Management System (DMS). The DMS is a complex, distributed, real-time computer system that has been redesigned numerous times. The implications of these redesigns have not been fully analyzed. This paper discusses the advantages and disadvantages for static analytical techniques such as Rate Monotonic Analysis (RMA) and also provides a rationale for dynamic modeling. Factors such as system architecture, processor utilization, bus architecture, queuing, etc. are well suited for analysis with a dynamic model. The significance of performance measures for a real-time system are discussed.

  8. National Energy Outlook Modelling System

    Energy Technology Data Exchange (ETDEWEB)

    Volkers, C.M. [ECN Policy Studies, Petten (Netherlands)

    2013-12-15

    For over 20 years, the Energy research Centre of the Netherlands (ECN) has been developing the National Energy Outlook Modelling System (NEOMS) for Energy projections and policy evaluations. NEOMS enables 12 energy models of ECN to exchange data and produce consistent and detailed results.

  9. ABSTRACT MODELS FOR SYSTEM VIRTUALIZATION

    Directory of Open Access Journals (Sweden)

    M. G. Koveshnikov

    2015-05-01

    Full Text Available The paper is dedicated to issues of system objects securing (system files and user system or application configuration files against unauthorized access including denial of service attacks. We have suggested the method and developed abstract system virtualization models, which are used toresearch attack scenarios for different virtualization modes. Estimation for system tools virtualization technology effectiveness is given. Suggested technology is based on redirection of access requests to system objects shared among access subjects. Whole and partial system virtualization modes have been modeled. The difference between them is the following: in the whole virtualization mode all copies of access system objects are created whereon subjects’ requests are redirected including corresponding application objects;in the partial virtualization mode corresponding copies are created only for part of a system, for example, only system objects for applications. Alternative solutions effectiveness is valued relating to different attack scenarios. We consider proprietary and approved technical solution which implements system virtualization method for Microsoft Windows OS family. Administrative simplicity and capabilities of correspondingly designed system objects security tools are illustrated on this example. Practical significance of the suggested security method has been confirmed.

  10. Aerodynamic and Mechanical System Modelling

    DEFF Research Database (Denmark)

    Jørgensen, Martin Felix

    This thesis deals with mechanical multibody-systems applied to the drivetrain of a 500 kW wind turbine. Particular focus has been on gearbox modelling of wind turbines. The main part of the present project involved programming multibody systems to investigate the connection between forces, moments...

  11. Experimental Modeling of Dynamic Systems

    DEFF Research Database (Denmark)

    Knudsen, Morten Haack

    2006-01-01

    An engineering course, Simulation and Experimental Modeling, has been developed that is based on a method for direct estimation of physical parameters in dynamic systems. Compared with classical system identification, the method appears to be easier to understand, apply, and combine with physical...

  12. Dissolved methane plume mapping using Membrane Inlet Mass-Spectrometry (MIMS) at a blow out site in the North Sea

    Science.gov (United States)

    Sommer, S.; Schmidt, M.; Linke, P.

    2012-04-01

    A blow out site in the North Sea (well 22/4-b, UK EEZ) in a water depth of 83 m, served as a test area to demonstrate MIMS as a powerful tool for the continuous measurement of dissolved methane simultaneously to the partial pressure of carbon dioxide, nitrogen and oxygen as well as other gases. A pump-CTD arrangement was used to generate a continuous water stream through a 2.5 cm thick tube to the ship laboratory and was analyzed using a membrane inlet quadrupole mass spectrometer (GAM 200, InProcessInstruments). The pump-CTD was further equipped with calibrated HydroC CH4/CO2 sensors. The MIMS measurements were conducted under fully controlled temperature conditions and were calibrated for CH4, N2, O2, and pCO2. The pump-CTD arrangement was towed along transects across the blow out and dissolved gas concentrations as well as physical water column data were synchronized and geo-referenced. The transects were repeated in three different depth layers, including a bottom layer of ~ 2 m above the sea floor, 60 m above the sea floor just below the thermocline and a third plane in 10 m water depth. During the tows water samples were taken for later onboard methane analysis and cross-calibration with the MIMS and HydroC data. After data selection under consideration of the tidal regime lateral and vertical plume dimensions of dissolved methane were constructed. Dissolved methane concentrations ranged between background and up to about 18µM. Below the thermocline, which represents an effective barrier for the vertical distribution of dissolved methane, methane distinctively spreads laterally. Only at locations were the gas bubble stream and concurrently advected water from below the thermocline reaches the sea surface enhanced methane emission into the atmosphere took place.

  13. Polymer Inclusion Membranes with Condensed Phase Membrane Introduction Mass Spectrometry (CP-MIMS): Improved Analytical Response Time and Sensitivity.

    Science.gov (United States)

    Vandergrift, Gregory W; Krogh, Erik T; Gill, Chris G

    2017-05-16

    Condensed phase membrane introduction mass spectrometry (CP-MIMS) is an online, in situ analysis technique for low volatility analytes. Analytes diffuse through a hollow fiber membrane, where they are then dissolved by a liquid (condensed) acceptor phase flowing through the membrane lumen. Permeating analytes are entrained to an atmospheric pressure ionization source for subsequent measurement by a mass spectrometer. Larger analytes, with inherently lower diffusivities, suffer from lengthy response times and lower sensitivity, limiting the use of CP-MIMS for their online, real-time measurement. We present the use of a heptane cosolvent in a methanol acceptor phase in combination with a polydimethylsiloxane (PDMS) membrane. The heptane generates an in situ polymer inclusion membrane (PIM) with the PDMS. We report improved measurement response times and greater sensitivity across a suite of analytes studied (gemfibrozil, nonylphenol, triclosan, 2,4,6-trichlorophenol, and naphthenic acids), with detection limits in the low parts per trillion (ppt) range. These improvements are attributed to increasing analyte diffusivities, as well as increased analyte partitioning across the PIM. Response times are ∼3× faster for the larger analytes studied, and calibration sensitivity is improved by up to ∼3.5× using 0.046 mole fraction heptane in the methanol acceptor. We report the use of short sample exposure times and the use of non-steady-state signals to reduce the analytical duty cycle, and illustrate that the use of a PIM provides a simple and robust variant of CP-MIMS amenable to rapid screening of analytes in complex samples.

  14. An extensible analysable system model

    DEFF Research Database (Denmark)

    Probst, Christian W.; Hansen, Rene Rydhof

    2008-01-01

    , this does not hold for real physical systems. Approaches such as threat modelling try to target the formalisation of the real-world domain, but still are far from the rigid techniques available in security research. Many currently available approaches to assurance of critical infrastructure security...... allows for easy development of analyses for the abstracted systems. We briefly present one application of our approach, namely the analysis of systems for potential insider threats....

  15. Evaluation of synthesis characterization and simulation study of magnetic nanoparticles for ammonia synthesis in MIM

    Science.gov (United States)

    Irfan, Muhammad; Yahya, Noorhana; Shafie, Afza; Soleimani, Hassan; Alqasem, Bilal; Rehman, Zia Ur; Qureshi, Saima

    2016-11-01

    It is generally understood that magnetic energy is much smaller than thermal energy which dominates the chemical equilibrium. Magnetic nanoparticles (NiO) as catalyst were synthesized by chemical reduction routes following micro emulsion method having an average size of 239 nm and 207.2 nm followed by FESEM and TEM analysis respectively. EDX analysis of nanoparticles (NPs) with 90.80 weight% Ni, 9.20 weight % O2 and 72.90 atomic% Ni, 27.10 atomic% O2 falls it into the category of formation of nickel and oxide NPs. TEM for parallel Ni EELs vs intensity is 840.0 eV to 860.0 eV and 70 to 80 respectively. TEM diffraction and fringe spacing analysis of NPs reveals the details about diffraction planes as (200), (311), (400) and lattice parameter 4.136 nm respectively. Both RAMAN spectroscopy and FTIR spectroscopy analysis of NPs elaborate the consistency between peak intensity and RAMAN shift (cm-1) as 318.74 cm-1, 522.78 cm-1, 620.28 cm-1 and 450 cm-1, 515.84 cm-1and 720.08 cm-1 respectively. The saturation magnetization (Ms) of NiO NPs was measured to be 32.524 emu/g by VSM for a specific mass of 14.1x10-3 g. Simulation study based on DFT in term of catalytic effect related to sorbents and sorbates atomistic, thermodynamic and quantum mechanical interactions including adsorption is illustrated in this article using first principal DFT simulation study. The average total energy, average total adsorption energy, average adsorption energy of H2, and N2 over NiO (111) surface are reported as 4.414 kcal/mol, 4.4145 kcal/mol, -1.671 kcal/mol, and 0.869 kcal/mol respectively. Whereas, isosteric heats of adsorption energies for H2, N2 over NiO (111) cleaved surface were calculated to 1.617kcal/mol, and -0.881 kcal/mol respectively. Ammonia synthesis carried out by MIM and peaks were detected by FTIR and yield was quantified by Kjeldahl method in few thousands μmole gcat-1 h-1.

  16. Modeling Multi-Level Systems

    CERN Document Server

    Iordache, Octavian

    2011-01-01

    This book is devoted to modeling of multi-level complex systems, a challenging domain for engineers, researchers and entrepreneurs, confronted with the transition from learning and adaptability to evolvability and autonomy for technologies, devices and problem solving methods. Chapter 1 introduces the multi-scale and multi-level systems and highlights their presence in different domains of science and technology. Methodologies as, random systems, non-Archimedean analysis, category theory and specific techniques as model categorification and integrative closure, are presented in chapter 2. Chapters 3 and 4 describe polystochastic models, PSM, and their developments. Categorical formulation of integrative closure offers the general PSM framework which serves as a flexible guideline for a large variety of multi-level modeling problems. Focusing on chemical engineering, pharmaceutical and environmental case studies, the chapters 5 to 8 analyze mixing, turbulent dispersion and entropy production for multi-scale sy...

  17. Reaching state-of-the art requirements for MIM capacitors with a single-layer anodic Al2O3 dielectric and imprinted electrodes

    Science.gov (United States)

    Hourdakis, Emmanouel; Nassiopoulou, Androula G.

    2017-07-01

    Metal-Insulator-Metal (MIM) capacitors with a high capacitance density and low non-linearity coefficient using a single-layer dielectric of barrier-type anodic alumina (Al2O3) and an imprinted bottom Al electrode are presented. Imprinting of the bottom electrode aimed at increasing the capacitor effective surface area by creating a three-dimensional MIM capacitor architecture. The bottom Al electrode was only partly nanopatterned so as to ensure low series resistance of the MIM capacitor. With a 3 nm thick anodic Al2O3 dielectric, the capacitor with the imprinted electrode showed a 280% increase in capacitance density compared to the flat electrode capacitor, reaching a value of 20.5 fF/μm2. On the other hand, with a 30 nm thick anodic Al2O3 layer, the capacitance density was 7.9 fF/μm2 and the non-linearity coefficient was as low as 196 ppm/V2. These values are very close to reaching all requirements of the last International Technology Roadmap for Semiconductors for MIM capacitors [ITRS, http://www.itrs2.net/2013-itrs.html for ITRS Roadmap (2013)], and they are achieved by a single-layer dielectric instead of the complicated dielectric stacks of the literature. The obtained results constitute a real progress compared to previously reported results by our group for MIM capacitors using imprinted electrodes.

  18. Distribution system modeling and analysis

    CERN Document Server

    Kersting, William H

    2002-01-01

    For decades, distribution engineers did not have the sophisticated tools developed for analyzing transmission systems-often they had only their instincts. Things have changed, and we now have computer programs that allow engineers to simulate, analyze, and optimize distribution systems. Powerful as these programs are, however, without a real understanding of the operating characteristics of a distribution system, engineers using the programs can easily make serious errors in their designs and operating procedures.Distribution System Modeling and Analysis helps prevent those errors. It gives re

  19. Stirling Engine Dynamic System Modeling

    Science.gov (United States)

    Nakis, Christopher G.

    2004-01-01

    The Thermo-Mechanical systems branch at the Glenn Research Center focuses a large amount time on Stirling engines. These engines will be used on missions where solar power is inefficient, especially in deep space. I work with Tim Regan and Ed Lewandowski who are currently developing and validating a mathematical model for the Stirling engines. This model incorporates all aspects of the system including, mechanical, electrical and thermodynamic components. Modeling is done through Simplorer, a program capable of running simulations of the model. Once created and then proven to be accurate, a model is used for developing new ideas for engine design. My largest specific project involves varying key parameters in the model and quantifying the results. This can all be done relatively trouble-free with the help of Simplorer. Once the model is complete, Simplorer will do all the necessary calculations. The more complicated part of this project is determining which parameters to vary. Finding key parameters depends on the potential for a value to be independently altered in the design. For example, a change in one dimension may lead to a proportional change to the rest of the model, and no real progress is made. Also, the ability for a changed value to have a substantial impact on the outputs of the system is important. Results will be condensed into graphs and tables with the purpose of better communication and understanding of the data. With the changing of these parameters, a more optimal design can be created without having to purchase or build any models. Also, hours and hours of results can be simulated in minutes. In the long run, using mathematical models can save time and money. Along with this project, I have many other smaller assignments throughout the summer. My main goal is to assist in the processes of model development, validation and testing.

  20. Tracer transfer in consolidated porous medium and fractured porous medium: experimentations and modelling; Transferts d'un traceur en milieu poreux consolide et en milieu poreux fissure: experimentations et modelisations

    Energy Technology Data Exchange (ETDEWEB)

    Dalla Costa, C

    2007-07-15

    We try to identify and model physical and chemical mechanisms governing the water flow and the solute transport in fractured consolidated porous medium. An original experimental device was built. The 'cube' consists of an idealized fractured medium reproduced by piling up consolidated porous cubes of 5 cm edge. Meanwhile, columns of the homogeneous consolidated porous medium are studied. The same anionic tracing technique is used in both cases. Using a system analysis approach, we inject concentration pulses in the device to obtain breakthrough curves. After identifying the mass balance and the residence time, we fit the CD and the MIM models to the experimental data. The MIM model is able to reproduce experimental curves of the homogeneous consolidated porous medium better than the CD model. The mobile water fraction is in accordance with the porous medium geometry. The study of the flow rate influence highlights an interference dispersion regime. It was not possible to highlight the observation length influence in this case. On the contrary, we highlight the effect of the observation scale on the fractured and porous medium, comparing the results obtained on a small 'cube' and a big 'cube'. The CD model is not satisfactory in this case. Even if the MIM model can fit the experimental breakthrough curves, it was not possible to obtain unique parameters for the set of experiments. (author)

  1. Kinetic Modeling of Biological Systems

    Energy Technology Data Exchange (ETDEWEB)

    Resat, Haluk; Petzold, Linda; Pettigrew, Michel F.

    2009-04-21

    The dynamics of how its constituent components interact define the spatio-temporal response of a natural system to stimuli. Modeling the kinetics of the processes that represent a biophysical system has long been pursued with the aim of improving our understanding of the studied system. Due to the unique properties of biological systems, in addition to the usual difficulties faced in modeling the dynamics of physical or chemical systems, biological simulations encounter difficulties that result from intrinsic multiscale and stochastic nature of the biological processes. This chapter discusses the implications for simulation of models involving interacting species with very low copy numbers, which often occur in biological systems and give rise to significant relative fluctuations. The conditions necessitating the use of stochastic kinetic simulation methods and the mathematical foundations of the stochastic simulation algorithms are presented. How the well-organized structural hierarchies often seen in biological systems can lead to multiscale problems, and possible ways to address the encountered computational difficulties are discussed. We present the details of the existing kinetic simulation methods, and discuss their strengths and shortcomings. A list of the publicly available kinetic simulation tools and our reflections for future prospects are also provided.

  2. Executive Information Systems' Multidimensional Models

    Directory of Open Access Journals (Sweden)

    2007-01-01

    Full Text Available Executive Information Systems are design to improve the quality of strategic level of management in organization through a new type of technology and several techniques for extracting, transforming, processing, integrating and presenting data in such a way that the organizational knowledge filters can easily associate with this data and turn it into information for the organization. These technologies are known as Business Intelligence Tools. But in order to build analytic reports for Executive Information Systems (EIS in an organization we need to design a multidimensional model based on the business model from the organization. This paper presents some multidimensional models that can be used in EIS development and propose a new model that is suitable for strategic business requests.

  3. Quantitative imaging of cells with multi-isotope imaging mass spectrometry (MIMS)—Nanoautography with stable isotope tracers

    Science.gov (United States)

    McMahon, Greg; Glassner, Brian J.; Lechene, Claude P.

    2006-07-01

    We describe some technical aspects of the application of multi-isotope imaging mass spectrometry (MIMS) to biological research, particularly the use of isotopic tags to localize and measure their incorporation into intracellular compartments. We touch on sample preparation, on image formation, on drift correction and on extraction of quantitative data from isotope ratio imaging. We insist on the wide variety of sample types that can be used, ranging from whole cells prepared directly on Si supports, to thin sections of cells and tissues on Si supports, to ultrathin TEM sections on carbon-coated grid. We attempt to dispel the myth of difficulties in sample preparation, which we view as a needless deterrent to the application of MIMS to the general biological community. We present protocols for the extraction of isotope ratio data from mass images. We illustrate the benefits of using sequential image plane acquisition followed by the application of an autocorrelation algorithm (nanotracking) to remove the effects of specimen drift. We insist on the advantages to display the isotope ratios as hue saturation intensity images.

  4. Removal of Nitrogen Compounds from Shale Diesel Fraction Using Ionic Liquid [C4mim]HSO4

    Institute of Scientific and Technical Information of China (English)

    Liu Jie; Ma Bo

    2016-01-01

    Ionic liquid (IL) 1-butyl-3-methylimidazolium hydrosulphate ([C4mim]HSO4) was synthesized and its denitroge-nation performance was investigated for diesel fraction with high content of nitride from oil shale. The effects of the tem-perature, the mass ratio of oil to IL, the mass ratio of water to IL, the extraction time, the settling time and the regeneration of IL on the N-removal efficiency were studied. Experimental results showed that the ionic liquid [C4mim]HSO4exhibited excellent denitrogenation performance, and about a 90% basic N-extraction efficiency and a 71% total N-extraction ef-ficiency were achieved under the conditions covering a temperature of 30℃, an oil/IL mass ratio of 7:1, a H2O/ IL mass ratio of 2:1, an extraction time of 20 min and a settling time of 120 min. In addition, the basic N-removal efficiency can still reach 74% during five recycles of the ionic liquid.

  5. Plasmonic nanogratings on MIM and SOI thin-film solar cells: comparison and optimization of optical and electric enhancements.

    Science.gov (United States)

    Heydari, Mehdi; Sabaeian, Mohammad

    2017-03-01

    In this work, Ag nanogratings comprised of arrays of nanostrips with three different cross sections of triangular, rectangular, and trapezoidal shape were considered and put at the top of the thin-film metal-insulator-metal (MIM) and semiconductor-on-insulator (SOI) solar cells. Then, the optical absorption and the short-circuit current density (JSC) enhancement (relative to a bare cell) were calculated and compared. In addition, the best strip cross section among three types of cross sections and the optimum grating period were found. The results showed that for the transverse electric (TE) mode, only the waveguide modes were excited inside the Si active layer with the assistance of Ag nanogratings. For the transverse magnetic (TM) mode, the waveguide as well as the localized surface plasmonic (LSP) modes were excited. The LSP modes, which were excited at the longer wavelengths centered on ∼600  nm, led to an additional and consequently a larger JSC enhancement. Finally, among the various types of plasmonic SOI and MIM solar cells, a SOI cell with a 300 nm grating period, comprised of rectangular nanostrips, showed a 40% enhancement in JSC, which is the highest possible value achieved in this work.

  6. Structural and Electrical Properties of Sol-Gel-Derived Lead Titanate Nanofilms with Different Pb Contents for MIM Capacitors

    Science.gov (United States)

    Nurbaya, Z.; Wahid, M. H.; Rozana, M. D.; Alrokayan, S. A. H.; Khan, H. A.; Gan, W. C.; Majid, W. H. A.; Rusop, M.

    2015-12-01

    Metal-insulator-metal (MIM) capacitors based on lead titanate (PbTiO3) nanofilms were prepared using a novel method involving modified spin coating onto the bare electrodes of a coated glass. Different solutions were prepared by adding different concentrations of lead acetate (PbAc) powder to improve the electrical properties of the PbTiO3 films. The nanofilms were characterized in terms of their surface morphology, dielectric properties, and current-voltage characteristics. Physical and dielectric properties are related to the increased PbAc content in the films prepared within the range of 5-25 wt.%. The films with 10 wt.% PbAc provide acceptable dielectric permittivity, low loss factor, and improved capacitance density at frequencies lower than 100 kHz. Low leakage current densities and high resistivity behavior can be obtained at approximately 10-7 A cm2. Therefore, the resultant films are suitable for MIM capacitor applications and exhibit potential for memory storage applications.

  7. Numerical Modeling of Microelectrochemical Systems

    DEFF Research Database (Denmark)

    Adesokan, Bolaji James

    for the reactants in the bulk electrolyte that are traveling waves. The first paper presents the mathematical model which describes an electrochemical system and simulates an electroanalytical technique called cyclic voltammetry. The model is governed by a system of advection–diffusion equations with a nonlinear...... reaction term at the boundary. We investigate the effect of flow rates, scan rates, and concentration on the cyclic voltammetry. We establish that high flow rates lead to the reduced hysteresis in the cyclic voltammetry curves and increasing scan rates lead to more pronounced current peaks. The final part...... of the paper shows that the response current in a cyclic voltammetry increases proportionally to the electrolyte concentration. In the second paper we present an experiment of an electrochemical system in a microfluidc system and compare the result to the numerical solutions. We investigate how the position...

  8. Quark Model and multiquark system

    CERN Document Server

    da Silva, Cristiane Oldoni

    2010-01-01

    The discovery of many particles, especially in the 50's, when the firsts accelerators appeared, caused the searching for a model that would describe in a simple form the whole of known particles. The Quark Model, based in the mathematical structures of group theory, provided in the beginning of the 60's a simplified description of hadronic matter already known, proposing that three particles, called quarks, would originate all the observed hadrons. This model was able to preview the existence of particles that were later detected, confirming its consistency. Extensions of the Quark Model were made in the beginning of the 70's, focusing in describing observed particles that were excited states of the fundamental particles and others that presented new quantum numbers (flavors). Recently, exotic states as tetraquarks and pentaquarks types, also called multiquarks systems, previewed by the model, were observed, what renewed the interest in the way as quarks are confined inside the hadrons. In this article we pre...

  9. Safety and efficacy of MIM D3 ophthalmic solutions in a randomized placebo controlled Phase 2 clinical trial in patients with dry eye

    Directory of Open Access Journals (Sweden)

    Meerovitch K

    2013-06-01

    Full Text Available Karen Meerovitch,1 Gail Torkildsen,2 John Lonsdale,3 Heidi Goldfarb,4 Teresa Lama,1 Garth Cumberlidge,1 George W Ousler III5 1Mimetogen Pharmaceuticals Inc, Montreal, QC, Canada; 2Andover Eye Associates, Andover, MA, USA; 3Central Maine Eye Care, Lewiston, ME, USA; 4SDC, Tempe, AZ, USA; 5Ora Inc, Andover, MA, USA Purpose: To evaluate the safety and efficacy of ophthalmic MIM-D3, a tyrosine kinase TrkA receptor agonist, in patients with dry eye. Design: A prospective, two-center, randomized, double-masked, placebo-controlled Phase 2 study. Methods: A total of 150 dry eye patients were randomized 1:1:1 to study medication (1% MIM-D3, 5% MIM-D3, or placebo and dosed twice daily (BID for 28 days. Key eligibility criteria included exacerbation in corneal staining and ocular discomfort in the Controlled Adverse Environment (CAESM on two visits, separated by 1 week of BID dosing with artificial tears. Safety and efficacy were evaluated at baseline, throughout treatment, and for 2 weeks post-treatment. The pre-specified primary outcome measures were fluorescein corneal staining post-CAE at day 28 and diary worst symptom scores over 28 days. Secondary outcomes included the pre-, post-, and the change from pre- to post-CAE fluorescein and lissamine green staining in both corneal and conjunctival regions, as well as individual diary symptoms. Results: The prespecified primary endpoints were not met. Compared with placebo, fluorescein corneal staining at day 28 was significantly improved (P < 0.05 in the 1% MIM-D3 group for the assessment of change from pre-CAE to post-CAE. In addition, following CAE exposure, patients in the 1% MIM-D3 group showed significant improvements versus placebo (P < 0.05 in inferior fluorescein and lissamine green staining after 14 and 28 days. Compared with placebo, patients in the 5% MIM-D3 group reported significantly lower daily diary scores for ocular dryness (P < 0.05. In a subgroup defined by higher symptom scores during

  10. GENERIC model for multiphase systems

    NARCIS (Netherlands)

    Sagis, L.M.C.

    2010-01-01

    GENERIC is a nonequilibrium thermodynamic formalism in which the dynamic behavior of a system is described by a single compact equation involving two types of brackets: a Poisson bracket and a dissipative bracket. This formalism has proved to be a very powerful instrument to model the dynamic behavi

  11. PHASE EQUILIBRIA FOR BINARY SYSTEMS CONTAINING IONIC LIQUID WITH WATER OR HYDROCARBONS

    Directory of Open Access Journals (Sweden)

    Dheiver Santos

    2015-12-01

    Full Text Available Abstract In this work, the mutual solubilities of sets of ionic liquids ([CnMIM] [TF2N] (n = 4, 8, 12, [C4PY] [TF2N], [C8MIM] [OTF] and organic compounds (heptane, o-xylene, toluene, or water are investigated. The experimental data measured for these systems were used to adjust the binary interaction parameters between their components for the Non-Random Two Liquid (NRTL model. The results showed that the solubility increased with temperature, with high hygroscopicity (10-1 in terms of mole fraction of the ILs, low interactions with aliphatic hydrocarbons, high interactions with aromatic hydrocarbons and the presence of a lower critical solution temperature (LCST. In addition, this study is the first to show that [C12MIM] [TF2N] is completely soluble in toluene and ortho-xylene between 273.15 and 373.15 K at 1 bar. The average deviations related to the mole fraction between the experimental and calculated values by the NRTL were less than 2.4%.

  12. Cotangent Models for Integrable Systems

    Science.gov (United States)

    Kiesenhofer, Anna; Miranda, Eva

    2017-03-01

    We associate cotangent models to a neighbourhood of a Liouville torus in symplectic and Poisson manifolds focusing on b-Poisson/ b-symplectic manifolds. The semilocal equivalence with such models uses the corresponding action-angle theorems in these settings: the theorem of Liouville-Mineur-Arnold for symplectic manifolds and an action-angle theorem for regular Liouville tori in Poisson manifolds (Laurent- Gengoux et al., IntMath Res Notices IMRN 8: 1839-1869, 2011). Our models comprise regular Liouville tori of Poisson manifolds but also consider the Liouville tori on the singular locus of a b-Poisson manifold. For this latter class of Poisson structures we define a twisted cotangent model. The equivalence with this twisted cotangent model is given by an action-angle theorem recently proved by the authors and Scott (Math. Pures Appl. (9) 105(1):66-85, 2016). This viewpoint of cotangent models provides a new machinery to construct examples of integrable systems, which are especially valuable in the b-symplectic case where not many sources of examples are known. At the end of the paper we introduce non-degenerate singularities as lifted cotangent models on b-symplectic manifolds and discuss some generalizations of these models to general Poisson manifolds.

  13. INTEGRATED HYDROGEN STORAGE SYSTEM MODEL

    Energy Technology Data Exchange (ETDEWEB)

    Hardy, B

    2007-11-16

    Hydrogen storage is recognized as a key technical hurdle that must be overcome for the realization of hydrogen powered vehicles. Metal hydrides and their doped variants have shown great promise as a storage material and significant advances have been made with this technology. In any practical storage system the rate of H2 uptake will be governed by all processes that affect the rate of mass transport through the bed and into the particles. These coupled processes include heat and mass transfer as well as chemical kinetics and equilibrium. However, with few exceptions, studies of metal hydrides have focused primarily on fundamental properties associated with hydrogen storage capacity and kinetics. A full understanding of the complex interplay of physical processes that occur during the charging and discharging of a practical storage system requires models that integrate the salient phenomena. For example, in the case of sodium alanate, the size of NaAlH4 crystals is on the order of 300nm and the size of polycrystalline particles may be approximately 10 times larger ({approx}3,000nm). For the bed volume to be as small as possible, it is necessary to densely pack the hydride particles. Even so, in packed beds composed of NaAlH{sub 4} particles alone, it has been observed that the void fraction is still approximately 50-60%. Because of the large void fraction and particle to particle thermal contact resistance, the thermal conductivity of the hydride is very low, on the order of 0.2 W/m-{sup o}C, Gross, Majzoub, Thomas and Sandrock [2002]. The chemical reaction for hydrogen loading is exothermic. Based on the data in Gross [2003], on the order of 10{sup 8}J of heat of is released for the uptake of 5 kg of H{sub 2}2 and complete conversion of NaH to NaAlH{sub 4}. Since the hydride reaction transitions from hydrogen loading to discharge at elevated temperatures, it is essential to control the temperature of the bed. However, the low thermal conductivity of the hydride

  14. Probabilistic models for feedback systems.

    Energy Technology Data Exchange (ETDEWEB)

    Grace, Matthew D.; Boggs, Paul T.

    2011-02-01

    In previous work, we developed a Bayesian-based methodology to analyze the reliability of hierarchical systems. The output of the procedure is a statistical distribution of the reliability, thus allowing many questions to be answered. The principal advantage of the approach is that along with an estimate of the reliability, we also can provide statements of confidence in the results. The model is quite general in that it allows general representations of all of the distributions involved, it incorporates prior knowledge into the models, it allows errors in the 'engineered' nodes of a system to be determined by the data, and leads to the ability to determine optimal testing strategies. In this report, we provide the preliminary steps necessary to extend this approach to systems with feedback. Feedback is an essential component of 'complexity' and provides interesting challenges in modeling the time-dependent action of a feedback loop. We provide a mechanism for doing this and analyze a simple case. We then consider some extensions to more interesting examples with local control affecting the entire system. Finally, a discussion of the status of the research is also included.

  15. Modeling Advance Life Support Systems

    Science.gov (United States)

    Pitts, Marvin; Sager, John; Loader, Coleen; Drysdale, Alan

    1996-01-01

    Activities this summer consisted of two projects that involved computer simulation of bioregenerative life support systems for space habitats. Students in the Space Life Science Training Program (SLSTP) used the simulation, space station, to learn about relationships between humans, fish, plants, and microorganisms in a closed environment. One student complete a six week project to modify the simulation by converting the microbes from anaerobic to aerobic, and then balancing the simulation's life support system. A detailed computer simulation of a closed lunar station using bioregenerative life support was attempted, but there was not enough known about system restraints and constants in plant growth, bioreactor design for space habitats and food preparation to develop an integrated model with any confidence. Instead of a completed detailed model with broad assumptions concerning the unknown system parameters, a framework for an integrated model was outlined and work begun on plant and bioreactor simulations. The NASA sponsors and the summer Fell were satisfied with the progress made during the 10 weeks, and we have planned future cooperative work.

  16. Minisuperspace models of discrete systems

    CERN Document Server

    Baytaş, Bekir

    2016-01-01

    A discrete quantum spin system is presented in which several modern methods of canonical quantum gravity can be tested with promising results. In particular, features of interacting dynamics are analyzed with an emphasis on homogeneous configurations and the dynamical building-up and stability of long-range correlations. Different types of homogeneous minisuperspace models are introduced for the system, including one based on condensate states, and shown to capture different aspects of the discrete system. They are evaluated with effective methods and by means of continuum limits, showing good agreement with operator calculations whenever the latter are available. As a possibly quite general result, it is concluded that an analysis of the building-up of long-range correlations in discrete systems requires non-perturbative solutions of the dynamical equations. Some questions related to stability can be analyzed perturbatively, but suggest that matter couplings may be relevant for this question in the context o...

  17. A new mobile-immobile model for reactive solute transport with scale-dependent dispersion

    Science.gov (United States)

    Gao, Guangyao; Zhan, Hongbin; Feng, Shaoyuan; Fu, Bojie; Ma, Ying; Huang, Guanhua

    2010-08-01

    This study proposed a new mobile-immobile model (MIM) to describe reactive solute transport with scale-dependent dispersion in heterogeneous porous media. The model was derived from the conventional MIM but assumed the dispersivity to be a linear or exponential function of travel distance. The linear adsorption and the first-order degradation of solute were also considered in the model. The Laplace transform technique and the de Hoog numerical Laplace inversion method were applied to solve the developed model. Solute breakthrough curves (BTCs) obtained from MIM with scale-dependent and constant dispersions were compared, and a constant effective dispersivity was provided to reflect the lumped scale-dependent dispersion effect. The effective dispersivity was calculated by arithmetically averaging the distance-dependent dispersivity. With this effective dispersivity, MIM could produce similar BTC as that from MIM with scale-dependent dispersion in porous media with moderate heterogeneity. The applicability of the proposed new model was tested with concentration data from a 1,250-cm long and highly heterogeneous soil column. The simulation results indicated that MIM with constant and linear distance-dependent dispersivities were unable to adequately describe the measured BTCs in the column, while MIM with exponential distance-dependent dispersivity satisfactorily captured the evolution of BTCs.

  18. 盐碱湖杆菌菌株MIM18的培养特性%Cultural Characteristics of a Bacterium,MIM18,Isolated from Salt Alkaline Lake

    Institute of Scientific and Technical Information of China (English)

    孟建宇; 李德林; 郑冬梅

    2013-01-01

    对分离自内蒙古自治区浑善达克盐碱湖的一株杆菌菌株MIM18的培养特征进行了研究.结果表明,该菌为革兰氏阳性杆菌,粉红色,分泌过氧化氢酶、精氨酸双水解酶和赖氨酸脱羧酶,对常见的抗生素高度敏感.生长盐浓度为0~55 g/L,最适盐浓度为10 g/L;温度范围24~40℃,最适温度33℃;pH 6.0~11.0,最适pH 9.5.好氧,属于兼性嗜碱菌.%The cultural characteristics of a strain,MIM18,isolated from the Hunshandake salt alkaline lake in Inner Mongolia were investigated.The results showed that the strain was found to be a gram-positive,rods and pink-pigmented bacterium,secreted catalase,arginine dihydrolase and lysine decarboxylase,was sensitive to common antibiotics.The strain was able to grow in 0~55 g/L total salts and the optimal concentration was 10 g/L.The range of temperature for this strain was 24~40 ℃ and the optimal temperature was 33 ℃.The range of pH was 6.0~ll.0 and the optimal pH was 9.5.This strain was aerobe and facultative alkalophile.

  19. The Control System Modeling Language

    CERN Document Server

    Zagar, K; Sekoranja, M; Tkacik, G; Vodovnik, A; Zagar, Klemen; Plesko, Mark; Sekoranja, Matej; Tkacik, Gasper; Vodovnik, Anze

    2001-01-01

    The well-known Unified Modeling Language (UML) describes software entities, such as interfaces, classes, operations and attributes, as well as relationships among them, e.g. inheritance, containment and dependency. The power of UML lies in Computer Aided Software Engineering (CASE) tools such as Rational Rose, which are also capable of generating software structures from visual object definitions and relations. UML also allows add-ons that define specific structures and patterns in order to steer and automate the design process. We have developed an add-on called Control System Modeling Language (CSML). It introduces entities and relationships that we know from control systems, such as "property" representing a single controllable point/channel, or an "event" specifying that a device is capable of notifying its clients through events. Entities can also possess CSML-specific characteristics, such as physical units and valid ranges for input parameters. CSML is independent of any specific language or technology...

  20. Contextual Modelling of Collaboration System

    Directory of Open Access Journals (Sweden)

    Wafaa DACHRY

    2012-03-01

    Full Text Available Faced with new environmental constraints, firms decide to collaborate in collective entities and adopt new patterns of behavior. So, this firms’ collaboration becomes an unavoidable approach. Indeed, our aim interest in our study is to propose a collaborative information system for supply chain. Our proposed platform ensures cooperation and information sharing between partners in real time. In fact, several questions have to be asked: What is the information nature may be shared between partners? What processes are implemented between actors? What functional services are supported by the platform? In order to answer these questions, we present, in this article, our methodological approach of modelling, called CMCS (Contextual Modelling of Collaborative System

  1. Stochastic Models of Polymer Systems

    Science.gov (United States)

    2016-01-01

    field limit of a dynamical model for polymer systems, Science China Mathematics , (11 2012): 0. doi: TOTAL: 1 Number of Non Peer-Reviewed Conference...4.0 (4.0 max scale): Number of graduating undergraduates funded by a DoD funded Center of Excellence grant for Education , Research and Engineering...undergraduates funded by your agreement who graduated during this period and will receive scholarships or fellowships for further studies in science

  2. Model reduction of parametrized systems

    CERN Document Server

    Ohlberger, Mario; Patera, Anthony; Rozza, Gianluigi; Urban, Karsten

    2017-01-01

    The special volume offers a global guide to new concepts and approaches concerning the following topics: reduced basis methods, proper orthogonal decomposition, proper generalized decomposition, approximation theory related to model reduction, learning theory and compressed sensing, stochastic and high-dimensional problems, system-theoretic methods, nonlinear model reduction, reduction of coupled problems/multiphysics, optimization and optimal control, state estimation and control, reduced order models and domain decomposition methods, Krylov-subspace and interpolatory methods, and applications to real industrial and complex problems. The book represents the state of the art in the development of reduced order methods. It contains contributions from internationally respected experts, guaranteeing a wide range of expertise and topics. Further, it reflects an important effor t, carried out over the last 12 years, to build a growing research community in this field. Though not a textbook, some of the chapters ca...

  3. Computational models of complex systems

    CERN Document Server

    Dabbaghian, Vahid

    2014-01-01

    Computational and mathematical models provide us with the opportunities to investigate the complexities of real world problems. They allow us to apply our best analytical methods to define problems in a clearly mathematical manner and exhaustively test our solutions before committing expensive resources. This is made possible by assuming parameter(s) in a bounded environment, allowing for controllable experimentation, not always possible in live scenarios. For example, simulation of computational models allows the testing of theories in a manner that is both fundamentally deductive and experimental in nature. The main ingredients for such research ideas come from multiple disciplines and the importance of interdisciplinary research is well recognized by the scientific community. This book provides a window to the novel endeavours of the research communities to present their works by highlighting the value of computational modelling as a research tool when investigating complex systems. We hope that the reader...

  4. Some Issues on Teaching and Research of MIM in Junior Schools%初中数学MIM教学与研究的几个问题

    Institute of Scientific and Technical Information of China (English)

    李吉宝; 李树臣

    2001-01-01

    MIM是指人们从事各种数学活动时,所表现出来的种种数学观念及思维方式.其结构的核心是数学观念和数学意识,以及数学思想、解题的一般方法和解题术.新的数学课程必须强化和渗透一些具有普遍意义MIM,MIM的教学可分为4个阶段:渗透与启迪阶段,意识与顿悟阶段,形成与应用阶段及深化与发展阶段.%It appeared to be more and more important to strengthen the teaching and rescarch of mathematical idea and methods (MIM). MIM was the mathematical views and thinking methods during the course of mathematics studying active. The core of MIM's structure contained mathematical view, mathcmatical conscious, mathematical idea, mcthods of problem solving. Modern mathematics teaching needed to show some MIM which could take effect anywhere.

  5. Development of a transient response technique for heterogeneous catalysis in liquid phase, Part 2: Applying membrane inlet mass spectrometry (MIMS) for detection of dissolved gasses.

    NARCIS (Netherlands)

    Radivojevic, D.; Ruitenbeek, M.; Seshan, Kulathuiyer; Lefferts, Leonardus

    2008-01-01

    A home-made analyzer for dissolved gasses in water, based on membrane inlet mass spectrometry (MIMS), was successfully applied for the first time as an in-line method for detection of gases dissolved in an aqueous stream, at the exit of a catalytic reactor in a transient experiment. The technique

  6. Evolution of microstructure and dimension of as-molded parts during thermal removal process of wax-based MIM binder

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The evolution of the microstructure and the dimension of as-molded parts were studied on the basis of the thermogravimetric analysis of wax-based MIM binder. The results show that the binder removal speeds are different in different temperature ranges during binder removal process. The evolution of the microstructure of as-molded parts during binder removal process clearly showed the initiation and formation of connected pore structure, which is the removal channel of the binder. The as-molded parts almost continuously shrank through binder removal process, except an expansion stage during 320~440  ℃, which is the dissolution expansion effect due to the dissolution of VPW in the polymer melt.

  7. Reconstitution of cellulose and lignin after [C2mim][OAc] pretreatment and its relation to enzymatic hydrolysis.

    Science.gov (United States)

    Yuan, Tong-Qi; Wang, Wei; Zhang, Li-Ming; Xu, Feng; Sun, Run-Cang

    2013-03-01

    Although the effects of cellulose crystallinity and lignin content as two major structural features on enzymatic hydrolysis have been extensively studied, debates regarding their effects still exist. In this study, reconstitution of cellulose and lignin after 1-ethyl-3-methylimidazolium acetate ([C(2)mim][OAc]) pretreatment was proposed as a new method to study their effects on enzymatic digestibility. Different mechanisms of lignin content for reduction of cellulose hydrolysis were found between the proposed method and the traditional method (mixing of cellulose and lignin). The results indicated that a slight change of the crystallinity of the reconstituted materials may play a minor role in the change of enzyme efficiency. In addition, the present study suggested that the lignin content does not significantly affect the digestibility of cellulose, whereas the conversion of cellulose fibers from the cellulose I to the cellulose II crystal phase plays an important role when an ionic liquid pretreatment of biomass was conducted. Copyright © 2012 Wiley Periodicals, Inc.

  8. Identification and Modelling of Linear Dynamic Systems

    Directory of Open Access Journals (Sweden)

    Stanislav Kocur

    2006-01-01

    Full Text Available System identification and modelling are very important parts of system control theory. System control is only as good as good is created model of system. So this article deals with identification and modelling problems. There are simple classification and evolution of identification methods, and then the modelling problem is described. Rest of paper is devoted to two most known and used models of linear dynamic systems.

  9. ISSM: Ice Sheet System Model

    Science.gov (United States)

    Larour, Eric; Schiermeier, John E.; Seroussi, Helene; Morlinghem, Mathieu

    2013-01-01

    In order to have the capability to use satellite data from its own missions to inform future sea-level rise projections, JPL needed a full-fledged ice-sheet/iceshelf flow model, capable of modeling the mass balance of Antarctica and Greenland into the near future. ISSM was developed with such a goal in mind, as a massively parallelized, multi-purpose finite-element framework dedicated to ice-sheet modeling. ISSM features unstructured meshes (Tria in 2D, and Penta in 3D) along with corresponding finite elements for both types of meshes. Each finite element can carry out diagnostic, prognostic, transient, thermal 3D, surface, and bed slope simulations. Anisotropic meshing enables adaptation of meshes to a certain metric, and the 2D Shelfy-Stream, 3D Blatter/Pattyn, and 3D Full-Stokes formulations capture the bulk of the ice-flow physics. These elements can be coupled together, based on the Arlequin method, so that on a large scale model such as Antarctica, each type of finite element is used in the most efficient manner. For each finite element referenced above, ISSM implements an adjoint. This adjoint can be used to carry out model inversions of unknown model parameters, typically ice rheology and basal drag at the ice/bedrock interface, using a metric such as the observed InSAR surface velocity. This data assimilation capability is crucial to allow spinning up of ice flow models using available satellite data. ISSM relies on the PETSc library for its vectors, matrices, and solvers. This allows ISSM to run efficiently on any parallel platform, whether shared or distrib- ISSM: Ice Sheet System Model NASA's Jet Propulsion Laboratory, Pasadena, California uted. It can run on the largest clusters, and is fully scalable. This allows ISSM to tackle models the size of continents. ISSM is embedded into MATLAB and Python, both open scientific platforms. This improves its outreach within the science community. It is entirely written in C/C++, which gives it flexibility in its

  10. Integrated Modeling for Flood Hazard Mapping Using Watershed Modeling System

    National Research Council Canada - National Science Library

    Seyedeh S. Sadrolashrafi; Thamer A. Mohamed; Ahmad R.B. Mahmud; Majid K. Kholghi; Amir Samadi

    2008-01-01

    ...) with the Watershed Modeling System (WMS) for flood modeling is developed. It also interconnects the terrain models and the GIS software, with commercial standard hydrological and hydraulic models, including HEC-1, HEC-RAS, etc...

  11. SO(2) saturation of the room temperature ionic liquid [C(2)mim][NTf(2)] much reduces the activation energy for diffusion.

    Science.gov (United States)

    Barrosse-Antle, Laura E; Hardacre, Christopher; Compton, Richard G

    2009-01-29

    The physical effect of high concentrations of reversibly dissolved SO(2) on [C(2)mim][NTf(2)] was examined using cyclic voltammetry, chronoamperometry, and ESR spectroscopy. Cyclic voltammetry of the oxidation of solutions of ferrocene, N,N,N',N'-tetramethyl-p-phenylenediamine (TMPD), and chloride in the room temperature ionic liquid (RTIL) 1-ethyl-3-methylimidazolium bis(trifluoromethanesufonyl)imide ([C(2)mim][NTf(2)]) reveals an increase in limiting current of each species corresponding to the addition of increasing concentrations of sulfur dioxide. Quantitative chronoamperometry reveals an increase in each species' diffusion coefficient with SO(2) concentration. When chronoamperometric data were obtained for ferrocene in [C(2)mim][NTf(2)] at a range of temperatures, the translational diffusion activation energy (29.0 +/- 0.5 kJ mol(- 1)) was found to be in good agreement with previous studies. Adding SO(2) results in apparent near-activationless translational diffusion. A significant decrease in the activation energy of rotational diffusion with the SO(2) saturation of a 2,2,6,6-tetramethyl-1-piperidinyloxyl (TEMPO) solution in [C(2)mim][NTf(2)] (29.9 +/- 2.0 to 7.7 +/- 5.3 kJ mol(- 1)) was observed using electron spin resonance (ESR) spectroscopy. The reversible physical absorption of SO(2) by [C(2)mim][NTf(2)] should have no adverse effect on the ability of that ionic liquid to be employed as a solvent in an electrochemical gas sensor, and it is possible that the SO(2)-mediated reduction of RTIL viscosity could have intrinsic utility.

  12. Network models in anatomical systems.

    Science.gov (United States)

    Esteve-Altava, Borja; Marugán-Lobón, Jesús; Botella, Héctor; Rasskin-Gutman, Diego

    2011-01-01

    Network theory has been extensively used to model the underlying structure of biological processes. From genetics to ecology, network thinking is changing our understanding of complex systems, specifically how their internal structure determines their overall behavior. Concepts such as hubs, scale-free or small-world networks, common in the complexity literature, are now used more and more in sociology, neurosciences, as well as other anthropological fields. Even though the use of network models is nowadays so widely applied, few attempts have been carried out to enrich our understanding in the classical morphological sciences such as in comparative anatomy or physical anthropology. The purpose of this article is to introduce the usage of network tools in morphology; specifically by building anatomical networks, dealing with the most common analyses and problems, and interpreting their outcome.

  13. Thermodynamic modeling of complex systems

    DEFF Research Database (Denmark)

    Liang, Xiaodong

    Offshore reservoirs represent one of the major growth areas of the oil and gas industry, and environmental safety is one of the biggest challenges for the offshore exploration and production. The oil accidents in the Gulf of Mexico in 1979 and 2010 were two of the biggest disasters in history...... after an oil spill. Engineering thermodynamics could be applied in the state-of-the-art sonar products through advanced artificial technology, if the speed of sound, solubility and density of oil-seawater systems could be satisfactorily modelled. The addition of methanol or glycols into unprocessed well...

  14. Models for Gaze Tracking Systems

    Directory of Open Access Journals (Sweden)

    Villanueva Arantxa

    2007-01-01

    Full Text Available One of the most confusing aspects that one meets when introducing oneself into gaze tracking technology is the wide variety, in terms of hardware equipment, of available systems that provide solutions to the same matter, that is, determining the point the subject is looking at. The calibration process permits generally adjusting nonintrusive trackers based on quite different hardware and image features to the subject. The negative aspect of this simple procedure is that it permits the system to work properly but at the expense of a lack of control over the intrinsic behavior of the tracker. The objective of the presented article is to overcome this obstacle to explore more deeply the elements of a video-oculographic system, that is, eye, camera, lighting, and so forth, from a purely mathematical and geometrical point of view. The main contribution is to find out the minimum number of hardware elements and image features that are needed to determine the point the subject is looking at. A model has been constructed based on pupil contour and multiple lighting, and successfully tested with real subjects. On the other hand, theoretical aspects of video-oculographic systems have been thoroughly reviewed in order to build a theoretical basis for further studies.

  15. Models for Gaze Tracking Systems

    Directory of Open Access Journals (Sweden)

    Arantxa Villanueva

    2007-10-01

    Full Text Available One of the most confusing aspects that one meets when introducing oneself into gaze tracking technology is the wide variety, in terms of hardware equipment, of available systems that provide solutions to the same matter, that is, determining the point the subject is looking at. The calibration process permits generally adjusting nonintrusive trackers based on quite different hardware and image features to the subject. The negative aspect of this simple procedure is that it permits the system to work properly but at the expense of a lack of control over the intrinsic behavior of the tracker. The objective of the presented article is to overcome this obstacle to explore more deeply the elements of a video-oculographic system, that is, eye, camera, lighting, and so forth, from a purely mathematical and geometrical point of view. The main contribution is to find out the minimum number of hardware elements and image features that are needed to determine the point the subject is looking at. A model has been constructed based on pupil contour and multiple lighting, and successfully tested with real subjects. On the other hand, theoretical aspects of video-oculographic systems have been thoroughly reviewed in order to build a theoretical basis for further studies.

  16. Area Logistics System Based on System Dynamics Model

    Institute of Scientific and Technical Information of China (English)

    GUI Shouping; ZHU Qiang; LU Lifang

    2005-01-01

    At present, there are few effective ways to analyze area logistics systems. This paper uses system dynamics to analyze the area logistics system and establishes a system dynamics model for the area logistics system based on the characteristics of the area logistics system and system dynamics. Numerical simulations with the system dynamic model were used to analyze a logistic system. Analysis of the Guangzhou economy shows that the model can reflect the actual state of the system objectively and can be used to make policy and harmonize environment.

  17. Enterprise Modelling supported by Manufacturing Systems Theory

    OpenAIRE

    MYKLEBUST, Odd

    2002-01-01

    There exist today a large number of enterprise models or enterprise modelling approaches. In a study of standards and project developed models there are two approaches: CIMOSA “The Open Systems Architecture for CIM” and GERAM, “Generalised Enterprise Reference Architecture”, which show a system orientation that can be further followed as interesting research topics for a system theory oriented approach for enterprise models. In the selection of system theories, manufacturing system theory...

  18. Modeling learning technology systems as business systems

    NARCIS (Netherlands)

    Avgeriou, Paris; Retalis, Symeon; Papaspyrou, Nikolaos

    2003-01-01

    The design of Learning Technology Systems, and the Software Systems that support them, is largely conducted on an intuitive, ad hoc basis, thus resulting in inefficient systems that defectively support the learning process. There is now justifiable, increasing effort in formalizing the engineering o

  19. Modeling learning technology systems as business systems

    NARCIS (Netherlands)

    Avgeriou, Paris; Retalis, Symeon; Papaspyrou, Nikolaos

    2003-01-01

    The design of Learning Technology Systems, and the Software Systems that support them, is largely conducted on an intuitive, ad hoc basis, thus resulting in inefficient systems that defectively support the learning process. There is now justifiable, increasing effort in formalizing the engineering

  20. Nonlinear System Identification and Behavioral Modeling

    CERN Document Server

    Huq, Kazi Mohammed Saidul; Kabir, A F M Sultanul

    2010-01-01

    The problem of determining a mathematical model for an unknown system by observing its input-output data pair is generally referred to as system identification. A behavioral model reproduces the required behavior of the original analyzed system, such as there is a one-to-one correspondence between the behavior of the original system and the simulated system. This paper presents nonlinear system identification and behavioral modeling using a work assignment.

  1. A View of Earth System Model Development

    Institute of Scientific and Technical Information of China (English)

    ZHOU Tianjun; YU Yongqiang; WANG Bin

    2009-01-01

    This paper gives a definition of earth system model and shows three development phases of it, including physical climate system model, earth climate system model, and earth system model, based on an inves-tigation of climate system models in the world. It provides an expatiation on the strategic significance of future development of earth system model, an introduction of some representative scientific research plans on development of earth system model home and abroad, and a review of its status and trends based on the models of the fourth assessment report (AR4) of the Intergovernmental Panel on Climate Change (IPCC).Some suggestions on future development of earth system model in China are given, which are expected to be helpful to advance the development.

  2. System identification application using Hammerstein model

    Indian Academy of Sciences (India)

    SABAN OZER; HASAN ZORLU; SELCUK METE

    2016-06-01

    Generally, memoryless polynomial nonlinear model for nonlinear part and finite impulse response (FIR) model or infinite impulse response model for linear part are preferred in Hammerstein models in literature. In this paper, system identification applications of Hammerstein model that is cascade of nonlinear second order volterra and linear FIR model are studied. Recursive least square algorithm is used to identify the proposed Hammerstein model parameters. Furthermore, the results are compared to identify the success of proposed Hammerstein model and different types of models

  3. Modeling of economic systems with Petri nets

    Directory of Open Access Journals (Sweden)

    Pavel Valeryevich Skorodumov

    2014-09-01

    Full Text Available Modeling is one of the most important tools to study complex systems. Components of both continuous and discrete nature are present in the behavior of contemporary economic systems. The article uses formalism of nested hybrid Petri nets as a tool to study complex economic systems. The author describes basic approaches of simulation modelling, concepts of classical Petri nets, modified means of nested hybrid Petri nets, benefits of their use for systems modeling. The article presents the concept of a universal system of simulation modeling. On the basis of considered approaches the article proposes to develop a universal system of simulation modeling on the basis of the modified machine Petri nets

  4. Modeling Power Systems as Complex Adaptive Systems

    Energy Technology Data Exchange (ETDEWEB)

    Chassin, David P.; Malard, Joel M.; Posse, Christian; Gangopadhyaya, Asim; Lu, Ning; Katipamula, Srinivas; Mallow, J V.

    2004-12-30

    Physical analogs have shown considerable promise for understanding the behavior of complex adaptive systems, including macroeconomics, biological systems, social networks, and electric power markets. Many of today's most challenging technical and policy questions can be reduced to a distributed economic control problem. Indeed, economically based control of large-scale systems is founded on the conjecture that the price-based regulation (e.g., auctions, markets) results in an optimal allocation of resources and emergent optimal system control. This report explores the state-of-the-art physical analogs for understanding the behavior of some econophysical systems and deriving stable and robust control strategies for using them. We review and discuss applications of some analytic methods based on a thermodynamic metaphor, according to which the interplay between system entropy and conservation laws gives rise to intuitive and governing global properties of complex systems that cannot be otherwise understood. We apply these methods to the question of how power markets can be expected to behave under a variety of conditions.

  5. Neuman systems model in holland: an update.

    Science.gov (United States)

    Merks, André; Verberk, Frans; de Kuiper, Marlou; Lowry, Lois W

    2012-10-01

    The authors of this column, leading members of the International Neuman Systems Model Association, provide an update on the use of Neuman systems model in Holland and document the various changes in The Netherlands that have influenced the use of the model in that country. The model's link to systems theory and stress theory are discussed, as well as a shift to greater emphasis on patient self-management. The model is also linked to healthcare quality improvement and interprofessional collaboration in Holland.

  6. New model systems for experimental evolution.

    Science.gov (United States)

    Collins, Sinéad

    2013-07-01

    Microbial experimental evolution uses a few well-characterized model systems to answer fundamental questions about how evolution works. This special section highlights novel model systems for experimental evolution, with a focus on marine model systems that can be used to understand evolutionary responses to global change in the oceans.

  7. Performance modeling of automated manufacturing systems

    Science.gov (United States)

    Viswanadham, N.; Narahari, Y.

    A unified and systematic treatment is presented of modeling methodologies and analysis techniques for performance evaluation of automated manufacturing systems. The book is the first treatment of the mathematical modeling of manufacturing systems. Automated manufacturing systems are surveyed and three principal analytical modeling paradigms are discussed: Markov chains, queues and queueing networks, and Petri nets.

  8. Modeling human operator involvement in robotic systems

    NARCIS (Netherlands)

    Wewerinke, P.H.

    1991-01-01

    A modeling approach is presented to describe complex manned robotic systems. The robotic system is modeled as a (highly) nonlinear, possibly time-varying dynamic system including any time delays in terms of optimal estimation, control and decision theory. The role of the human operator(s) is modeled

  9. Visual computing model for immune system and medical system.

    Science.gov (United States)

    Gong, Tao; Cao, Xinxue; Xiong, Qin

    2015-01-01

    Natural immune system is an intelligent self-organizing and adaptive system, which has a variety of immune cells with different types of immune mechanisms. The mutual cooperation between the immune cells shows the intelligence of this immune system, and modeling this immune system has an important significance in medical science and engineering. In order to build a comprehensible model of this immune system for better understanding with the visualization method than the traditional mathematic model, a visual computing model of this immune system was proposed and also used to design a medical system with the immune system, in this paper. Some visual simulations of the immune system were made to test the visual effect. The experimental results of the simulations show that the visual modeling approach can provide a more effective way for analyzing this immune system than only the traditional mathematic equations.

  10. Externalizing Behaviour for Analysing System Models

    NARCIS (Netherlands)

    Ivanova, Marieta Georgieva; Probst, Christian W.; Hansen, René Rydhof; Kammüller, Florian

    Systems models have recently been introduced to model organisationsandevaluate their vulnerability to threats and especially insiderthreats. Especially for the latter these models are very suitable, since insiders can be assumed to have more knowledge about the attacked organisation than outside

  11. CONTROL SYSTEM IDENTIFICATION THROUGH MODEL MODULATION METHODS

    Science.gov (United States)

    identification has been achieved by using model modulation techniques to drive dynamic models into correspondence with operating control systems. The system ... identification then proceeded from examination of the model and the adaptive loop. The model modulation techniques applied to adaptive control

  12. Two sustainable energy system analysis models

    DEFF Research Database (Denmark)

    Lund, Henrik; Goran Krajacic, Neven Duic; da Graca Carvalho, Maria

    2005-01-01

    This paper presents a comparative study of two energy system analysis models both designed with the purpose of analysing electricity systems with a substantial share of fluctuating renewable energy.......This paper presents a comparative study of two energy system analysis models both designed with the purpose of analysing electricity systems with a substantial share of fluctuating renewable energy....

  13. A mobile information management system used in textile enterprises

    Energy Technology Data Exchange (ETDEWEB)

    Huang, C-R; Yu, W-D [College of Textiles, Donghua University, 1882 west Yan-an Road, Shanghai 200051 (China)], E-mail: wdyu@dhu.edu.cn

    2008-02-15

    The mobile information management system (MIMS) for textile enterprises is based on Microsoft Visual Studios. NET2003 Server, Microsoft SQL Server 2000, C{sup ++} language and wireless application protocol (WAP) and wireless markup language (WML) technology. The portable MIMS is composed of three-layer structures, i.e. showing layer; operating layer; and data visiting layer corresponding to the port-link module; processing module; and database module. By using the MIMS, not only the information exchanges become more convenient and easier, but also the compatible between the giant information capacity and a micro-cell phone and functional expansion nature in operating and designing can be realized by means of build-in units. The development of MIMS is suitable for the utilization in textile enterprises.

  14. A mobile information management system used in textile enterprises

    Science.gov (United States)

    Huang, C.-R.; Yu, W.-D.

    2008-02-01

    The mobile information management system (MIMS) for textile enterprises is based on Microsoft Visual Studios. NET2003 Server, Microsoft SQL Server 2000, C++ language and wireless application protocol (WAP) and wireless markup language (WML) technology. The portable MIMS is composed of three-layer structures, i.e. showing layer; operating layer; and data visiting layer corresponding to the port-link module; processing module; and database module. By using the MIMS, not only the information exchanges become more convenient and easier, but also the compatible between the giant information capacity and a micro-cell phone and functional expansion nature in operating and designing can be realized by means of build-in units. The development of MIMS is suitable for the utilization in textile enterprises.

  15. Graphical Model Debugger Framework for Embedded Systems

    DEFF Research Database (Denmark)

    Zeng, Kebin; Guo, Yu; Angelov, Christo K.

    2010-01-01

    Model Driven Software Development has offered a faster way to design and implement embedded real-time software by moving the design to a model level, and by transforming models to code. However, the testing of embedded systems has remained at the code level. This paper presents a Graphical Model...... Debugger Framework, providing an auxiliary avenue of analysis of system models at runtime by executing generated code and updating models synchronously, which allows embedded developers to focus on the model level. With the model debugger, embedded developers can graphically test their design model...

  16. Particle Tracking Model (PTM) with Coastal Modeling System (CMS)

    Science.gov (United States)

    2014-10-31

    System ( CMS ) 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER...www.erdc.usace.army.mil/Missions/WaterResources/CIRP.aspx Coastal Inlets Research Program Particle Tracking Model (PTM) with Coastal Modeling System ( CMS ) The...System ( CMS ), which provides coupled wave and current forcing for PTM simulations. CMS -PTM is implemented in the Surface-water Modeling System, a

  17. Analysis hierarchical model for discrete event systems

    Science.gov (United States)

    Ciortea, E. M.

    2015-11-01

    The This paper presents the hierarchical model based on discrete event network for robotic systems. Based on the hierarchical approach, Petri network is analysed as a network of the highest conceptual level and the lowest level of local control. For modelling and control of complex robotic systems using extended Petri nets. Such a system is structured, controlled and analysed in this paper by using Visual Object Net ++ package that is relatively simple and easy to use, and the results are shown as representations easy to interpret. The hierarchical structure of the robotic system is implemented on computers analysed using specialized programs. Implementation of hierarchical model discrete event systems, as a real-time operating system on a computer network connected via a serial bus is possible, where each computer is dedicated to local and Petri model of a subsystem global robotic system. Since Petri models are simplified to apply general computers, analysis, modelling, complex manufacturing systems control can be achieved using Petri nets. Discrete event systems is a pragmatic tool for modelling industrial systems. For system modelling using Petri nets because we have our system where discrete event. To highlight the auxiliary time Petri model using transport stream divided into hierarchical levels and sections are analysed successively. Proposed robotic system simulation using timed Petri, offers the opportunity to view the robotic time. Application of goods or robotic and transmission times obtained by measuring spot is obtained graphics showing the average time for transport activity, using the parameters sets of finished products. individually.

  18. Extensions in model-based system analysis

    OpenAIRE

    Graham, Matthew R.

    2007-01-01

    Model-based system analysis techniques provide a means for determining desired system performance prior to actual implementation. In addition to specifying desired performance, model-based analysis techniques require mathematical descriptions that characterize relevant behavior of the system. The developments of this dissertation give ex. tended formulations for control- relevant model estimation as well as model-based analysis conditions for performance requirements specified as frequency do...

  19. Inductive modelling of an entrepreneurial system

    OpenAIRE

    Yearworth, M

    2010-01-01

    We describe the development of a novel approach to generating theory about the behaviour of an entrepreneurial or start-up system. The new technology business creation system in and around the cities of Bath and Bristol in the UK was analysed using an inductive modelling approach that hybridises grounded theory with system dynamics, a technique we have called grounded systems modelling. Three models that represent the stages of development of an idea through to successful exploitation have be...

  20. Control model for reconfigurable assembly systems

    Institute of Scientific and Technical Information of China (English)

    Yu Jianfeng; Yin Yuehong; Chen Zhaoneng

    2005-01-01

    This paper proposes knowledge based object-oriented timed colored Petri net, a modeling method for reconfigurable assembly systems. Combining knowledge and object-oriented method into timed colored Petri net, a comprehensive and powerful representation model for control of RAS is obtained. With object-oriented method the whole system can be decomposed into concrete objects explicitly, and their relationships are constructed according to the system assembly requirements. Finally, a simple assembly system modeled by the KTCOPN is presented.

  1. Modelling Immune System: Principles, Models,Analysis and Perspectives

    Institute of Scientific and Technical Information of China (English)

    Xiang-hua Li; Zheng-xuan Wang; Tian-yang Lu; Xiang-jiu Che

    2009-01-01

    The biological immune system is a complex adaptive system. There are lots of benefits for building the model of the immune system. For biological researchers, they can test some hypotheses about the infection process or simulate the responses of some drugs. For computer researchers, they can build distributed, robust and fault tolerant networks inspired by the functions of the immune system. This paper provides a comprehensive survey of the literatures on modelling the immune system. From the methodology perspective, the paper compares and analyzes the existing approaches and models, and also demonstrates the focusing research effort on the future immune models in the next few years.

  2. Comparison of Photovoltaic Models in the System Advisor Model: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Blair, N. J.; Dobos, A. P.; Gilman, P.

    2013-08-01

    The System Advisor Model (SAM) is free software developed by the National Renewable Energy Laboratory (NREL) for predicting the performance of renewable energy systems and analyzing the financial feasibility of residential, commercial, and utility-scale grid-connected projects. SAM offers several options for predicting the performance of photovoltaic (PV) systems. The model requires that the analyst choose from three PV system models, and depending on that choice, possibly choose from three module and two inverter component models. To obtain meaningful results from SAM, the analyst must be aware of the differences between the model options and their applicability to different modeling scenarios. This paper presents an overview the different PV model options and presents a comparison of results for a 200-kW system using different model options.

  3. Graphical Model Debugger Framework for Embedded Systems

    DEFF Research Database (Denmark)

    Zeng, Kebin

    2010-01-01

    Debugger Framework, providing an auxiliary avenue of analysis of system models at runtime by executing generated code and updating models synchronously, which allows embedded developers to focus on the model level. With the model debugger, embedded developers can graphically test their design model......Model Driven Software Development has offered a faster way to design and implement embedded real-time software by moving the design to a model level, and by transforming models to code. However, the testing of embedded systems has remained at the code level. This paper presents a Graphical Model...... and check the running status of the system, which offers a debugging capability on a higher level of abstraction. The framework intends to contribute a tool to the Eclipse society, especially suitable for model-driven development of embedded systems....

  4. Reactive-Atom Scattering from Liquid Crystals at the Liquid-Vacuum Interface: [C12mim][BF4] and 4-Cyano-4'-Octylbiphenyl (8CB).

    Science.gov (United States)

    Purcell, Simon M; Tesa-Serrate, Maria A; Marshall, Brooks C; Bruce, Duncan W; D'Andrea, Lucía; Costen, Matthew L; Slattery, John M; Smoll, Eric J; Minton, Timothy K; McKendrick, Kenneth G

    2016-10-04

    Two complementary approaches were used to study the liquid-vacuum interface of the liquid-crystalline ionic liquid 1-dodecyl-3-methylimidazolium tetrafluoroborate ([C12mim][BF4]) in the smectic A (SmA) and isotropic phases. O atoms with two distinct incident translational energies were scattered from the surface of [C12mim][BF4]. Angle-dependent time-of-flight distributions and OH yields, respectively, were recorded from high- and low-energy O atoms. There were no significant changes in the measurements using either approach, nor the properties derived from them, accompanying the transition from the SmA to the isotropic phase. This indicates that the surface structure of [C12mim][BF4] remains essentially unchanged across the phase boundary, implying that the bulk order and surface structure are not strongly correlated for this material. This effect is ascribed to the strong propensity for the outer surfaces of ionic liquids to be dominated by alkyl chains, over an underlying layer rich in anions and cation head groups, whether or not the bulk material is a liquid crystal. In a comparative study, the OH yield from the surface of the liquid crystal, 8CB, was found to be affected by the bulk order, showing a surprising step increase at the SmA-nematic transition temperature, whose origin is the subject of speculation.

  5. Molecular dynamics simulation of the interfacial structure of [C(n)mim][PF6] adsorbed on a graphite surface: effects of temperature and alkyl chain length.

    Science.gov (United States)

    Dou, Q; Sha, M L; Fu, H Y; Wu, G Z

    2011-05-01

    The structures and diffusion behaviors of a series of ionic liquids [C(n)mim][PF(6)] (n = 1, 4, 8 and 12) on a graphite surface have been investigated by means of molecular dynamics simulation. It was found that three or four ordering layers of ionic liquids were formed near the graphite surface, and this layering structure was stable over the temperature range investigated. At the liquid/vacuum interface, the ionic liquid with a butyl chain had a monolayer ordering surface, while [C(8)mim][PF(6)] and [C(12)mim][PF(6)] exhibited a bilayer ordering with a polar domain sandwiched between two orientational nonpolar domains. More impressively, the simulated results showed that for the ionic liquids with alkyl chains longer than C(4), the adjacent alkyl chains in the whole film tended to be parallel to each other, with the imidazolium rings packed closely together. This indicated that the ionic liquids have a better regulated short-range structure than was previously expected. It was also found that both in the bottom layer and in the bulk region, the diffusion of the alkyl chains was much faster than that of the polar groups. However, as the alkyl chain length increased, the charge delocalization in the cation and the enhanced van der Waals interaction between the nonpolar groups contributed by reducing this difference in the diffusivity of major groups.

  6. 沙丁胺醇在离子液体[BnMIM]PF6修饰碳糊电极上的电催化氧化及电分析方法%Electrocatalytic Oxidation of Salbutamol at a [BnMIM]PF6 Modified Carbon Paste Electrode and Its Electrochemical Determination

    Institute of Scientific and Technical Information of China (English)

    吴锐; 马少宁; 张艳梅; 高作宁

    2013-01-01

    The electrocatalytic oxidation and electrochemical kinetic of Salbutamol (SAL) were investigated at a 1-Benzyl-3-Methylimidazole hexafluorophosphate([BnMIM]PF6) modified carbon paste electrode([BnMIM]PF6/CPE).The experimental results showed that the [BnMIM]PF6/CPE showed an excellent electrocatalytic activity toward SAL.The reaction rate constant for catalytic oxidation k was obtained as (2.10± 0.05) × 103 (mol· L-1)-1 · s-1 by chronoamperometry(CA).The catalytic oxidation peak current of SAL and its concentration had a good linear relationship in the range of 6.0× 10-7-1.0×10-3 mol· L-1,with a detection limit of 3.7 × 10-8 mol· L 1 (S/N=3) obtained by differential pulse voltammetry (DPV).The proposed method has been successfully applied in the electrochemical quantitative determination of SAL content in the commercial inhaled salbutamol solution.%研究了沙丁胺醇(Salbutamol,SAL)在离子液体1-苄基-3-甲基咪唑六氟磷酸盐([BnMIM]PF6)修饰碳糊电极([BnMIM]PF6/CPE)上的电催化氧化行为和电化学动力学性质.实验结果表明,[BnMIM]PF6/CPE对SAL的电化学氧化具有良好的催化作用.用计时电流法(CA)测定了SAL在[BnMIM] PF6/CPE上的电催化氧化反应速率常数k为(2.10±0.05)×103(mol·L-1)1·s-1.用微分脉冲伏安法(DPV)测得催化氧化峰电流与SAL的浓度在6.0×10-7~1.0×10-3mol· L-1范围内呈良好线性关系,检测限(S/N=3)为3.27×10-8 mol·L-1,同时运用该方法对吸入用沙丁胺醇溶液中的SAL含量进行了电化学定量测定.

  7. Modeling and Identification of Multirate Systems

    Institute of Scientific and Technical Information of China (English)

    Feng DING; Tongwen CHEN

    2005-01-01

    Multirate systems are abundant in industry; for example, many soft-sensor design problems are related to modeling, parameter identification, or state estimation involving multirate systems. The study of multirate systems goes back to the early 1950's, and has become an active research area in systems and control. This paper briefly surveys the history of development in the area of multirate systems, and introduces some basic concepts and latest results on multirate systems, including a polynomial transformation technique and the lifting technique as tools for handling multirate systems, lifted state space models, parameter identification of dual-rate systems, how to determine fast single-rate models from dual-rate models and directly from dual-rate data, and a hierarchical identification method for general multirate systems. Finally, some further research topics for multirate systems are given.

  8. On Problems of Multicomponent System Maintenance Modelling

    Institute of Scientific and Technical Information of China (English)

    Tomasz Nowakowski; Sylwia Werbinka

    2009-01-01

    We present an overview of some recent developments in the area of mathematical modeling of maintenance decisions for multi-unit systems. The emphasis is on three main groups of multicomponent maintenance optimization models: the block replacement models, group maintenance models, and opportunistic maintenance models. Moreover, an example of a two-unit system maintenance process is provided in order to compare various maintenance policies.

  9. Traffic Modeling in WCDMA System Level Simulations

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Traffic modeling is a crucial element in WCDMA system level simulations. A clear understanding of the nature of traffic in the WCDMA system and subsequent selection of an appropriate random traffic model are critical to the success of the modeling enterprise. The resultant performances will evidently be of a function that our design has been well adapted to the traffic, channel and user mobility models, and these models are also accurate. In this article, our attention will be focused on modeling voice and WWW data traffic with the SBBP model and Victor model respectively.

  10. Towards Modelling of Hybrid Systems

    DEFF Research Database (Denmark)

    Wisniewski, Rafal

    2006-01-01

    The article is an attempt to use methods of category theory and topology for analysis of hybrid systems. We use the notion of a directed topological space; it is a topological space together with a set of privileged paths. Dynamical systems are examples of directed topological spaces. A hybrid...... system consists of a number of dynamical systems that are glued together according to information encoded in the discrete part of the system. We develop a definition of a hybrid system as a functor from the category generated by a transition system to the category of directed topological spaces. Its...... directed homotopy colimit (geometric realization) is a single directed topological space. The behavior of hybrid systems can be then understood in terms of the behavior of dynamical systems through the directed homotopy colimit....

  11. Federated data bases for the development of an operational monitoring and forecasting system of the ocean: the THREDDS Dataset Merger

    Directory of Open Access Journals (Sweden)

    S. Nativi

    2006-01-01

    Full Text Available During the last decade, operational monitoring and forecasting systems have been developed in all the European seas. The exchange of data and products and the development of services for a wide community of users pose some fundamental issues, whose solution has become a priority in integrated and GMES referring projects, such as the MERSEA European project. These projects aim to develop a European system for operational monitoring and forecasting on global and regional scales of ocean physics, bio-chemistry and ecosystems. GMES system and its operational projects need to federate resources and expertise coming from diverse organizations working on different Earth Sciences fields (e.g. satellite data processing, in situ observing systems, data management, ocean and ecosystem modeling, etc.. Therefore, it is required a Marine Information Management (MIM system capable of facilitating the regular real-time exchange of high quality information, data and products. Moreover, MIM system must provide appropriate information for a wide range of external users both in real-time and delayed mode. In this paper an architecture based on the OPeNDAP/THREDDS technology is proposed as a solution for these operational systems. In this context, a catalog merging solution is introduced for the MIM system, which results in the design and development of the THREDDS Dataset Merger (TDM: a set of services meant to merge THREDDS Dataset Inventory Catalogs, so to achieve a unique catalog service for a whole database federation. TDM service merges distributed and autonomous THREDDS catalogs in order to work out a virtual merged catalog. The TDM service was extended in order to provide automatic catalogs synchronization. This service allows extending the pull-based TDM paradigm to support push-based applications. Some security issues are also considered.

  12. Service systems concepts, modeling, and programming

    CERN Document Server

    Cardoso, Jorge; Poels, Geert

    2014-01-01

    This SpringerBrief explores the internal workings of service systems. The authors propose a lightweight semantic model for an effective representation to capture the essence of service systems. Key topics include modeling frameworks, service descriptions and linked data, creating service instances, tool support, and applications in enterprises.Previous books on service system modeling and various streams of scientific developments used an external perspective to describe how systems can be integrated. This brief introduces the concept of white-box service system modeling as an approach to mo

  13. Hydrological modelling in forested systems

    Science.gov (United States)

    This chapter provides a brief overview of forest hydrology modelling approaches for answering important global research and management questions. Many hundreds of hydrological models have been applied globally across multiple decades to represent and predict forest hydrological p...

  14. Modeling, Control and Coordination of Helicopter Systems

    CERN Document Server

    Ren, Beibei; Chen, Chang; Fua, Cheng-Heng; Lee, Tong Heng

    2012-01-01

    Modeling, Control and Coordination of Helicopter Systems provides a comprehensive treatment of helicopter systems, ranging from related nonlinear flight dynamic modeling and stability analysis to advanced control design for single helicopter systems, and also covers issues related to the coordination and formation control of multiple helicopter systems to achieve high performance tasks. Ensuring stability in helicopter flight is a challenging problem for nonlinear control design and development. This book is a valuable reference on modeling, control and coordination of helicopter systems,providing readers with practical solutions for the problems that still plague helicopter system design and implementation. Readers will gain a complete picture of helicopters at the systems level, as well as a better understanding of the technical intricacies involved. This book also: Presents a complete picture of modeling, control and coordination for helicopter systems Provides a modeling platform for a general class of ro...

  15. Electronic Education System Model-2

    Science.gov (United States)

    Güllü, Fatih; Kuusik, Rein; Laanpere, Mart

    2015-01-01

    In this study we presented new EES Model-2 extended from EES model for more productive implementation in e-learning process design and modelling in higher education. The most updates were related to uppermost instructional layer. We updated learning processes object of the layer for adaptation of educational process for young and old people,…

  16. Network and adaptive system of systems modeling and analysis.

    Energy Technology Data Exchange (ETDEWEB)

    Lawton, Craig R.; Campbell, James E. Dr. (.; .); Anderson, Dennis James; Eddy, John P.

    2007-05-01

    This report documents the results of an LDRD program entitled ''Network and Adaptive System of Systems Modeling and Analysis'' that was conducted during FY 2005 and FY 2006. The purpose of this study was to determine and implement ways to incorporate network communications modeling into existing System of Systems (SoS) modeling capabilities. Current SoS modeling, particularly for the Future Combat Systems (FCS) program, is conducted under the assumption that communication between the various systems is always possible and occurs instantaneously. A more realistic representation of these communications allows for better, more accurate simulation results. The current approach to meeting this objective has been to use existing capabilities to model network hardware reliability and adding capabilities to use that information to model the impact on the sustainment supply chain and operational availability.

  17. On Verification Modelling of Embedded Systems

    NARCIS (Netherlands)

    Brinksma, Ed; Mader, Angelika

    2004-01-01

    Computer-aided verification of embedded systems hinges on the availability of good verification models of the systems at hand. Such models must be much simpler than full design models or specifications to be of practical value, because of the unavoidable combinatorial complexities in the verificatio

  18. Applying Modeling Tools to Ground System Procedures

    Science.gov (United States)

    Di Pasquale, Peter

    2012-01-01

    As part of a long-term effort to revitalize the Ground Systems (GS) Engineering Section practices, Systems Modeling Language (SysML) and Business Process Model and Notation (BPMN) have been used to model existing GS products and the procedures GS engineers use to produce them.

  19. Identification of F- and SO42- as the radiolytic products of the ionic liquid C4mimNTf2 and their effect on the extraction of UO22+

    Science.gov (United States)

    Sun, Taoxiang; Shen, Xinghai; Chen, Qingde; Ma, Jingyuan; Zhang, Shuo; Huang, Yuying

    2013-02-01

    A precipitate was found at the interface between the aqueous phase and the ionic liquid (IL) phase during the separation of UO22+/Eu3+ using irradiated IL 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imides (C4mimNTf2), and was analyzed by SEM, EDS, XPS and PXRD. The anions F- and SO42- were identified as the radiolytic products of C4mimNTf2. The radiation effect on the extraction of UO22+ from aqueous solution by tri-n-butyl phosphate (TBP) in C4mimNTf2 was studied. For the presence of F- and SO42-, the utilization of irradiated C4mimNTf2 as diluent reduced the extraction efficiency of UO22+. The EXAFS measurement showed that the degradation of C4mimNTf2 insignificantly influenced the coordination environment of UO22+ in the IL phase. Furthermore, it was suggested that the complex of uranyl ion with four TBP molecules is predominant during the extraction of UO22+ by TBP in C4mimNTf2 from aqueous solution in the absence of nitric acid. This work gives a further assessment for the application of ILs in the processing of spent nuclear fuel.

  20. System Level Modelling and Performance Estimation of Embedded Systems

    DEFF Research Database (Denmark)

    Tranberg-Hansen, Anders Sejer

    is simulation based and allows performance estimation to be carried out throughout all design phases ranging from early functional to cycle accurate and bit true descriptions of the system, modelling both hardware and software components in a unied way. Design space exploration and performance estimation...... an efficient system level design methodology, a modelling framework for performance estimation and design space exploration at the system level is required. This thesis presents a novel component based modelling framework for system level modelling and performance estimation of embedded systems. The framework...... is performed by having the framework produce detailed quantitative information about the system model under investigation. The project is part of the national Danish research project, Danish Network of Embedded Systems (DaNES), which is funded by the Danish National Advanced Technology Foundation. The project...

  1. EXPOSURE ANALYSIS MODELING SYSTEM (EXAMS): USER MANUAL AND SYSTEM DOCUMENTATION

    Science.gov (United States)

    The Exposure Analysis Modeling System, first published in 1982 (EPA-600/3-82-023), provides interactive computer software for formulating aquatic ecosystem models and rapidly evaluating the fate, transport, and exposure concentrations of synthetic organic chemicals - pesticides, ...

  2. SU-E-J-89: Comparative Analysis of MIM and Velocity’s Image Deformation Algorithm Using Simulated KV-CBCT Images for Quality Assurance

    Energy Technology Data Exchange (ETDEWEB)

    Cline, K; Narayanasamy, G; Obediat, M; Stanley, D; Stathakis, S; Kirby, N [University of Texas Health Science Center at San Antonio, Cancer Therapy and Research Center, San Antonio, TX (United States); Kim, H [University of California San Francisco, San Francisco, CA (United States)

    2015-06-15

    Purpose: Deformable image registration (DIR) is used routinely in the clinic without a formalized quality assurance (QA) process. Using simulated deformations to digitally deform images in a known way and comparing to DIR algorithm predictions is a powerful technique for DIR QA. This technique must also simulate realistic image noise and artifacts, especially between modalities. This study developed an algorithm to create simulated daily kV cone-beam computed-tomography (CBCT) images from CT images for DIR QA between these modalities. Methods: A Catphan and physical head-and-neck phantom, with known deformations, were used. CT and kV-CBCT images of the Catphan were utilized to characterize the changes in Hounsfield units, noise, and image cupping that occur between these imaging modalities. The algorithm then imprinted these changes onto a CT image of the deformed head-and-neck phantom, thereby creating a simulated-CBCT image. CT and kV-CBCT images of the undeformed and deformed head-and-neck phantom were also acquired. The Velocity and MIM DIR algorithms were applied between the undeformed CT image and each of the deformed CT, CBCT, and simulated-CBCT images to obtain predicted deformations. The error between the known and predicted deformations was used as a metric to evaluate the quality of the simulated-CBCT image. Ideally, the simulated-CBCT image registration would produce the same accuracy as the deformed CBCT image registration. Results: For Velocity, the mean error was 1.4 mm for the CT-CT registration, 1.7 mm for the CT-CBCT registration, and 1.4 mm for the CT-simulated-CBCT registration. These same numbers were 1.5, 4.5, and 5.9 mm, respectively, for MIM. Conclusion: All cases produced similar accuracy for Velocity. MIM produced similar values of accuracy for CT-CT registration, but was not as accurate for CT-CBCT registrations. The MIM simulated-CBCT registration followed this same trend, but overestimated MIM DIR errors relative to the CT

  3. Pǎun's systems as models of economic systems

    Institute of Scientific and Technical Information of China (English)

    Waldemar Korczynski

    2007-01-01

    In the paper a concept for modeling the economic systems by the formalism of Pǎun's systems is proposed. The main idea is to represent economic systems as homomorphic images of Petri nets corresponding to the (super) cells of Pǎun's systems.

  4. Modeling Control Situations in Power System Operations

    DEFF Research Database (Denmark)

    Saleem, Arshad; Lind, Morten; Singh, Sri Niwas

    2010-01-01

    Increased interconnection and loading of the power system along with deregulation has brought new challenges for electric power system operation, control and automation. Traditional power system models used in intelligent operation and control are highly dependent on the task purpose. Thus, a model...... for intelligent operation and control must represent system features, so that information from measurements can be related to possible system states and to control actions. These general modeling requirements are well understood, but it is, in general, difficult to translate them into a model because of the lack...... of explicit principles for model construction. This paper presents a work on using explicit means-ends model based reasoning about complex control situations which results in maintaining consistent perspectives and selecting appropriate control action for goal driven agents. An example of power system...

  5. Modeling Control Situations in Power System Operations

    DEFF Research Database (Denmark)

    Saleem, Arshad; Lind, Morten; Singh, Sri Niwas

    2010-01-01

    Increased interconnection and loading of the power system along with deregulation has brought new challenges for electric power system operation, control and automation. Traditional power system models used in intelligent operation and control are highly dependent on the task purpose. Thus, a model...... for intelligent operation and control must represent system features, so that information from measurements can be related to possible system states and to control actions. These general modeling requirements are well understood, but it is, in general, difficult to translate them into a model because of the lack...... of explicit principles for model construction. This paper presents a work on using explicit means-ends model based reasoning about complex control situations which results in maintaining consistent perspectives and selecting appropriate control action for goal driven agents. An example of power system...

  6. Modeling noisy resonant system response

    Science.gov (United States)

    Weber, Patrick Thomas; Walrath, David Edwin

    2017-02-01

    In this paper, a theory-based model replicating empirical acoustic resonant signals is presented and studied to understand sources of noise present in acoustic signals. Statistical properties of empirical signals are quantified and a noise amplitude parameter, which models frequency and amplitude-based noise, is created, defined, and presented. This theory-driven model isolates each phenomenon and allows for parameters to be independently studied. Using seven independent degrees of freedom, this model will accurately reproduce qualitative and quantitative properties measured from laboratory data. Results are presented and demonstrate success in replicating qualitative and quantitative properties of experimental data.

  7. Generic Model Host System Design

    Energy Technology Data Exchange (ETDEWEB)

    Chu, Chungming; /SLAC; Wu, Juhao; /SLAC; Qiang, Ji; /LBL, Berkeley; Shen, Guobao; /Brookhaven

    2012-06-22

    There are many simulation codes for accelerator modelling; each one has some strength but not all. A platform which can host multiple modelling tools would be ideal for various purposes. The model platform along with infrastructure support can be used not only for online applications but also for offline purposes. Collaboration is formed for the effort of providing such a platform. In order to achieve such a platform, a set of common physics data structure has to be set. Application Programming Interface (API) for physics applications should also be defined within a model data provider. A preliminary platform design and prototype is discussed.

  8. Four MATLAB-Simulink models ofphotovoltaic system

    Directory of Open Access Journals (Sweden)

    Jawad Radhi Mahmood, Nasir Hussein Selman

    2016-01-01

    Full Text Available This paper presents four different MATLAB models to simulate the output I-V and P-V characteristics of photovoltaic (PV cells or systems. All of the models are implemented with Matlab-Simulink. Detailed modeling procedure for one-diode equivalent circuit model with all equations and numerical values is presented. The parameters required for the modeling have been taken from manufacturer's datasheet for 240W SOLIMPEKS solar panel. I-V and P-V characteristics of a typical 1.92 kW PV system have been simulated using the proposed models. The simulation took into account the sunlight insolation and temperature effect. Results of the models are validated with I-V and P-V curves provided by the manufacturer(s. The proposed models are very useful for those interested in working in the field of solar systems because they emulate and analyze the characteristics of all the solar systems easily.

  9. CTL Model Update for System Modifications

    CERN Document Server

    Ding, Yulin; Zhang, Yan; Zhang, Y; 10.1613/jair.2420

    2011-01-01

    Model checking is a promising technology, which has been applied for verification of many hardware and software systems. In this paper, we introduce the concept of model update towards the development of an automatic system modification tool that extends model checking functions. We define primitive update operations on the models of Computation Tree Logic (CTL) and formalize the principle of minimal change for CTL model update. These primitive update operations, together with the underlying minimal change principle, serve as the foundation for CTL model update. Essential semantic and computational characterizations are provided for our CTL model update approach. We then describe a formal algorithm that implements this approach. We also illustrate two case studies of CTL model updates for the well-known microwave oven example and the Andrew File System 1, from which we further propose a method to optimize the update results in complex system modifications.

  10. Computational Models for Nonlinear Aeroelastic Systems Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Clear Science Corp. and Duke University propose to develop and demonstrate new and efficient computational methods of modeling nonlinear aeroelastic systems. The...

  11. Model Updating Nonlinear System Identification Toolbox Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ZONA Technology (ZONA) proposes to develop an enhanced model updating nonlinear system identification (MUNSID) methodology that utilizes flight data with...

  12. Modeling and analysis of biomass production systems

    Energy Technology Data Exchange (ETDEWEB)

    Mishoe, J.W.; Lorber, M.N.; Peart, R.M.; Fluck, R.C.; Jones, J.W.

    1984-01-01

    BIOMET is an interactive simulation model that is used to analyze specific biomass and methane production systems. The system model is composed of crop growth models, harvesting, transportation, conversion and economic submodels. By use of menus the users can configure the structure and set selected parameters of the system to analyze the effects of variables within the component models. For example, simulations of a water hyacinth system resulted in yields of 63, 48 and 37 mg/ha/year for different harvest schedules. For napier grass, unit methane costs were $3.04, $2.86 and $2.98 for various yields of biomass. 10 references.

  13. Error Propagation in a System Model

    Science.gov (United States)

    Schloegel, Kirk (Inventor); Bhatt, Devesh (Inventor); Oglesby, David V. (Inventor); Madl, Gabor (Inventor)

    2015-01-01

    Embodiments of the present subject matter can enable the analysis of signal value errors for system models. In an example, signal value errors can be propagated through the functional blocks of a system model to analyze possible effects as the signal value errors impact incident functional blocks. This propagation of the errors can be applicable to many models of computation including avionics models, synchronous data flow, and Kahn process networks.

  14. Hydrological modeling in forested systems

    Science.gov (United States)

    H.E. Golden; G.R. Evenson; S. Tian; Devendra Amatya; Ge Sun

    2015-01-01

    Characterizing and quantifying interactions among components of the forest hydrological cycle is complex and usually requires a combination of field monitoring and modelling approaches (Weiler and McDonnell, 2004; National Research Council, 2008). Models are important tools for testing hypotheses, understanding hydrological processes and synthesizing experimental data...

  15. Stochastic Modelling of Energy Systems

    DEFF Research Database (Denmark)

    Andersen, Klaus Kaae

    2001-01-01

    equations are expressed in terms of stochastic differential equations. From a theoretical viewpoint the techniques for experimental design, parameter estimation and model validation are considered. From the practical viewpoint emphasis is put on how this methods can be used to construct models adequate...

  16. Stochastic Modelling of Hydrologic Systems

    DEFF Research Database (Denmark)

    Jonsdottir, Harpa

    2007-01-01

    In this PhD project several stochastic modelling methods are studied and applied on various subjects in hydrology. The research was prepared at Informatics and Mathematical Modelling at the Technical University of Denmark. The thesis is divided into two parts. The first part contains an introduct......In this PhD project several stochastic modelling methods are studied and applied on various subjects in hydrology. The research was prepared at Informatics and Mathematical Modelling at the Technical University of Denmark. The thesis is divided into two parts. The first part contains...... an introduction and an overview of the papers published. Then an introduction to basic concepts in hydrology along with a description of hydrological data is given. Finally an introduction to stochastic modelling is given. The second part contains the research papers. In the research papers the stochastic methods...

  17. Hypervirial Models of Stellar Systems

    CERN Document Server

    Evans, N W

    2005-01-01

    A family of cusped potential-density pairs is introduced for modelling galaxies and dark haloes. The density profile is cusped like 1/r^(2-p) at small radii. The distribution function takes the simple form L^(p-2) E^([3p+1]/2) (where E is the binding energy and L is the angular momentum). The models all possess the remarkable property that the virial theorem holds locally, from which they earn their name as the hypervirial family. Famously, this property was first discovered by Eddington to hold for the Plummer model in 1916. In fact, the seductive properties of the Plummer model extend to the whole hypervirial family, including the members possessing the cosmologically important cusps with density behaving like 1/r or 1/r^1.5 or 1/r^1.33. The intrinsic and projected properties of the family of models are discussed in some detail.

  18. Semantic models for adaptive interactive systems

    CERN Document Server

    Hussein, Tim; Lukosch, Stephan; Ziegler, Jürgen; Calvary, Gaëlle

    2013-01-01

    Providing insights into methodologies for designing adaptive systems based on semantic data, and introducing semantic models that can be used for building interactive systems, this book showcases many of the applications made possible by the use of semantic models.Ontologies may enhance the functional coverage of an interactive system as well as its visualization and interaction capabilities in various ways. Semantic models can also contribute to bridging gaps; for example, between user models, context-aware interfaces, and model-driven UI generation. There is considerable potential for using

  19. Model reduction of linear conservative mechanical systems

    NARCIS (Netherlands)

    Schaft, van der A.J.; Oeloff, J.E.

    1990-01-01

    An approach for model reduction of linear conservative or weakly damped mechanical systems is proposed. It is based on the balancing of an associated gradient system. It uses the joint knowledge of the system matrix and the input and output matrices of the Hamiltonian system. The key idea is to asso

  20. Modeling complex work systems - method meets reality

    OpenAIRE

    Veer, van der, C.G.; Hoeve, Machteld; Lenting, Bert F.

    1996-01-01

    Modeling an existing task situation is often a first phase in the (re)design of information systems. For complex systems design, this model should consider both the people and the organization involved, the work, and situational aspects. Groupware Task Analysis (GTA) as part of a method for the design of complex systems, has been applied in a situation of redesign of a Dutch public administration system. The most feasible method to collect information in this case was ethnography, the resulti...

  1. Modeling of power electronic systems with EMTP

    Science.gov (United States)

    Tam, Kwa-Sur; Dravid, Narayan V.

    1989-01-01

    In view of the potential impact of power electronics on power systems, there is need for a computer modeling/analysis tool to perform simulation studies on power systems with power electronic components as well as to educate engineering students about such systems. The modeling of the major power electronic components of the NASA Space Station Freedom Electric Power System is described along with ElectroMagnetic Transients Program (EMTP) and it is demonstrated that EMTP can serve as a very useful tool for teaching, design, analysis, and research in the area of power systems with power electronic components. EMTP modeling of power electronic circuits is described and simulation results are presented.

  2. Models of the venous system

    DEFF Research Database (Denmark)

    Mehlsen, J

    2000-01-01

    of the venous system require at least three elements: a resistor, a capacitor and an inductor, with the latter being of more importance in the venous than in the arterial system. Non-linearities must be considered in pressure/flow relations in the small venules, during venous collapse, or low flow conditions...

  3. Learning Markov models for stationary system behaviors

    DEFF Research Database (Denmark)

    Chen, Yingke; Mao, Hua; Jaeger, Manfred

    2012-01-01

    Establishing an accurate model for formal verification of an existing hardware or software system is often a manual process that is both time consuming and resource demanding. In order to ease the model construction phase, methods have recently been proposed for automatically learning accurate...... system models from data in the form of observations of the target system. Common for these approaches is that they assume the data to consist of multiple independent observation sequences. However, for certain types of systems, in particular many running embedded systems, one would only have access...... the learned model. Experiments demonstrate that system properties (formulated as stationary probabilities of LTL formulas) can be reliably identified using the learned model....

  4. Integrating systems biology models and biomedical ontologies

    Directory of Open Access Journals (Sweden)

    de Bono Bernard

    2011-08-01

    Full Text Available Abstract Background Systems biology is an approach to biology that emphasizes the structure and dynamic behavior of biological systems and the interactions that occur within them. To succeed, systems biology crucially depends on the accessibility and integration of data across domains and levels of granularity. Biomedical ontologies were developed to facilitate such an integration of data and are often used to annotate biosimulation models in systems biology. Results We provide a framework to integrate representations of in silico systems biology with those of in vivo biology as described by biomedical ontologies and demonstrate this framework using the Systems Biology Markup Language. We developed the SBML Harvester software that automatically converts annotated SBML models into OWL and we apply our software to those biosimulation models that are contained in the BioModels Database. We utilize the resulting knowledge base for complex biological queries that can bridge levels of granularity, verify models based on the biological phenomenon they represent and provide a means to establish a basic qualitative layer on which to express the semantics of biosimulation models. Conclusions We establish an information flow between biomedical ontologies and biosimulation models and we demonstrate that the integration of annotated biosimulation models and biomedical ontologies enables the verification of models as well as expressive queries. Establishing a bi-directional information flow between systems biology and biomedical ontologies has the potential to enable large-scale analyses of biological systems that span levels of granularity from molecules to organisms.

  5. Integrating systems biology models and biomedical ontologies

    Science.gov (United States)

    2011-01-01

    Background Systems biology is an approach to biology that emphasizes the structure and dynamic behavior of biological systems and the interactions that occur within them. To succeed, systems biology crucially depends on the accessibility and integration of data across domains and levels of granularity. Biomedical ontologies were developed to facilitate such an integration of data and are often used to annotate biosimulation models in systems biology. Results We provide a framework to integrate representations of in silico systems biology with those of in vivo biology as described by biomedical ontologies and demonstrate this framework using the Systems Biology Markup Language. We developed the SBML Harvester software that automatically converts annotated SBML models into OWL and we apply our software to those biosimulation models that are contained in the BioModels Database. We utilize the resulting knowledge base for complex biological queries that can bridge levels of granularity, verify models based on the biological phenomenon they represent and provide a means to establish a basic qualitative layer on which to express the semantics of biosimulation models. Conclusions We establish an information flow between biomedical ontologies and biosimulation models and we demonstrate that the integration of annotated biosimulation models and biomedical ontologies enables the verification of models as well as expressive queries. Establishing a bi-directional information flow between systems biology and biomedical ontologies has the potential to enable large-scale analyses of biological systems that span levels of granularity from molecules to organisms. PMID:21835028

  6. Very Large System Dynamics Models - Lessons Learned

    Energy Technology Data Exchange (ETDEWEB)

    Jacob J. Jacobson; Leonard Malczynski

    2008-10-01

    This paper provides lessons learned from developing several large system dynamics (SD) models. System dynamics modeling practice emphasize the need to keep models small so that they are manageable and understandable. This practice is generally reasonable and prudent; however, there are times that large SD models are necessary. This paper outlines two large SD projects that were done at two Department of Energy National Laboratories, the Idaho National Laboratory and Sandia National Laboratories. This paper summarizes the models and then discusses some of the valuable lessons learned during these two modeling efforts.

  7. Precipitation-runoff modeling system; user's manual

    Science.gov (United States)

    Leavesley, G.H.; Lichty, R.W.; Troutman, B.M.; Saindon, L.G.

    1983-01-01

    The concepts, structure, theoretical development, and data requirements of the precipitation-runoff modeling system (PRMS) are described. The precipitation-runoff modeling system is a modular-design, deterministic, distributed-parameter modeling system developed to evaluate the impacts of various combinations of precipitation, climate, and land use on streamflow, sediment yields, and general basin hydrology. Basin response to normal and extreme rainfall and snowmelt can be simulated to evaluate changes in water balance relationships, flow regimes, flood peaks and volumes, soil-water relationships, sediment yields, and groundwater recharge. Parameter-optimization and sensitivity analysis capabilites are provided to fit selected model parameters and evaluate their individual and joint effects on model output. The modular design provides a flexible framework for continued model system enhancement and hydrologic modeling research and development. (Author 's abstract)

  8. Network model of security system

    Directory of Open Access Journals (Sweden)

    Adamczyk Piotr

    2016-01-01

    Full Text Available The article presents the concept of building a network security model and its application in the process of risk analysis. It indicates the possibility of a new definition of the role of the network models in the safety analysis. Special attention was paid to the development of the use of an algorithm describing the process of identifying the assets, vulnerability and threats in a given context. The aim of the article is to present how this algorithm reduced the complexity of the problem by eliminating from the base model these components that have no links with others component and as a result and it was possible to build a real network model corresponding to reality.

  9. Evaluation Model of System Survivability

    Institute of Scientific and Technical Information of China (English)

    LIU Yuling; PAN Shiying; TIAN Junfeng

    2006-01-01

    This paper puts forward a survivability evaluation model, SQEM(Survivability Quantitative Evaluation Model), based on lucubrating the main method existed. Then it defines the measurement factors and parses the survivability mathematically, introduces state change probability and the idea of setting the weights of survivability factors dynamically into the evaluating process of SQEM, which improved the accuracy of evaluation. An example is presented to illustrate the way SQEM works, which demonstrated the validity and feasibility of the method.

  10. Brief history of agricultural systems modeling.

    Science.gov (United States)

    Jones, James W; Antle, John M; Basso, Bruno; Boote, Kenneth J; Conant, Richard T; Foster, Ian; Godfray, H Charles J; Herrero, Mario; Howitt, Richard E; Janssen, Sander; Keating, Brian A; Munoz-Carpena, Rafael; Porter, Cheryl H; Rosenzweig, Cynthia; Wheeler, Tim R

    2017-07-01

    Agricultural systems science generates knowledge that allows researchers to consider complex problems or take informed agricultural decisions. The rich history of this science exemplifies the diversity of systems and scales over which they operate and have been studied. Modeling, an essential tool in agricultural systems science, has been accomplished by scientists from a wide range of disciplines, who have contributed concepts and tools over more than six decades. As agricultural scientists now consider the "next generation" models, data, and knowledge products needed to meet the increasingly complex systems problems faced by society, it is important to take stock of this history and its lessons to ensure that we avoid re-invention and strive to consider all dimensions of associated challenges. To this end, we summarize here the history of agricultural systems modeling and identify lessons learned that can help guide the design and development of next generation of agricultural system tools and methods. A number of past events combined with overall technological progress in other fields have strongly contributed to the evolution of agricultural system modeling, including development of process-based bio-physical models of crops and livestock, statistical models based on historical observations, and economic optimization and simulation models at household and regional to global scales. Characteristics of agricultural systems models have varied widely depending on the systems involved, their scales, and the wide range of purposes that motivated their development and use by researchers in different disciplines. Recent trends in broader collaboration across institutions, across disciplines, and between the public and private sectors suggest that the stage is set for the major advances in agricultural systems science that are needed for the next generation of models, databases, knowledge products and decision support systems. The lessons from history should be

  11. Information modeling system for blast furnace control

    Science.gov (United States)

    Spirin, N. A.; Gileva, L. Y.; Lavrov, V. V.

    2016-09-01

    Modern Iron & Steel Works as a rule are equipped with powerful distributed control systems (DCS) and databases. Implementation of DSC system solves the problem of storage, control, protection, entry, editing and retrieving of information as well as generation of required reporting data. The most advanced and promising approach is to use decision support information technologies based on a complex of mathematical models. The model decision support system for control of blast furnace smelting is designed and operated. The basis of the model system is a complex of mathematical models created using the principle of natural mathematical modeling. This principle provides for construction of mathematical models of two levels. The first level model is a basic state model which makes it possible to assess the vector of system parameters using field data and blast furnace operation results. It is also used to calculate the adjustment (adaptation) coefficients of the predictive block of the system. The second-level model is a predictive model designed to assess the design parameters of the blast furnace process when there are changes in melting conditions relative to its current state. Tasks for which software is developed are described. Characteristics of the main subsystems of the blast furnace process as an object of modeling and control - thermal state of the furnace, blast, gas dynamic and slag conditions of blast furnace smelting - are presented.

  12. MODELING AND ANALYSIS OF REGIONAL BOUNDARY SYSTEM

    Institute of Scientific and Technical Information of China (English)

    YAN Guangle; WANG Huanchen

    2001-01-01

    In this paper, the problems of modeling and analyzing the system with change able boundary are researched. First, a kind of expanding system is set up, in which the changeable boundary is dealt with as a regional boundary. Then some relative models are developed to describe the regional boundary system. Next, the transition or the driftage of bifurcation points in the system is discussed. A fascinating case is studied in which two or more than two classes of chaotic attractive points coexist together or exist alternatively in the same system. Lastly, an effective new method of chaos avoidance for the system is put forward.

  13. Formal heterogeneous system modeling with SystemC

    DEFF Research Database (Denmark)

    Niaki, Seyed Hosein Attarzadeh; Jakobsen, Mikkel Koefoed; Sulonen, Tero;

    2012-01-01

    Electronic System Level (ESL) design of embedded systems proposes raising the abstraction level of the design entry to cope with the increasing complexity of such systems. To exploit the benefits of ESL, design languages should allow specification of models which are a) heterogeneous, to describe...... different aspects of systems; b) formally defined, for application of analysis and synthesis methods; c) executable, to enable early detection of specification; and d) parallel, to exploit the multi- and many-core platforms for simulation and implementation. We present a modeling library on top of System......C, targeting heterogeneous embedded system design, based on four models of computation. The library has a formal basis where all elements are well defined and lead in construction of analyzable models. The semantics of communication and computation are implemented by the library, which allows the designer...

  14. Grey Box Modelling of Hydrological Systems

    DEFF Research Database (Denmark)

    Thordarson, Fannar Ørn

    The main topic of the thesis is grey box modelling of hydrologic systems, as well as formulation and assessment of their embedded uncertainties. Grey box model is a combination of a white box model, a physically-based model that is traditionally formulated using deterministic ordinary differential...... the lack of fit in state space formulation, and further support decisions for a model expansion. By using stochastic differential equations to formulate the dynamics of the hydrological system, either the complexity of the model can be increased by including the necessary hydrological processes...... in the model, or formulation of process noise can be considered so that it meets the physical limits of the hydrological system and give an adequate description of the embedded uncertainty in model structure. The thesis consists of two parts: a summary report and a part which contains six scientific papers...

  15. A Model-Based Systems Engineering Methodology for Employing Architecture In System Analysis: Developing Simulation Models Using Systems Modeling Language Products to Link Architecture and Analysis

    Science.gov (United States)

    2016-06-01

    ENGINEERING METHODOLOGY FOR EMPLOYING ARCHITECTURE IN SYSTEM ANALYSIS: DEVELOPING SIMULATION MODELS USING SYSTEMS MODELING LANGUAGE PRODUCTS TO LINK... ENGINEERING METHODOLOGY FOR EMPLOYING ARCHITECTURE IN SYSTEM ANALYSIS: DEVELOPING SIMULATION MODELS USING SYSTEMS MODELING LANGUAGE PRODUCTS TO LINK...to model-based systems engineering (MBSE) by formally defining an MBSE methodology for employing architecture in system analysis (MEASA) that presents

  16. System Advisor Model: Flat Plate Photovoltaic Performance Modeling Validation Report

    Energy Technology Data Exchange (ETDEWEB)

    Freeman, J.; Whitmore, J.; Kaffine, L.; Blair, N.; Dobos, A. P.

    2013-12-01

    The System Advisor Model (SAM) is a free software tool that performs detailed analysis of both system performance and system financing for a variety of renewable energy technologies. This report provides detailed validation of the SAM flat plate photovoltaic performance model by comparing SAM-modeled PV system generation data to actual measured production data for nine PV systems ranging from 75 kW to greater than 25 MW in size. The results show strong agreement between SAM predictions and field data, with annualized prediction error below 3% for all fixed tilt cases and below 8% for all one axis tracked cases. The analysis concludes that snow cover and system outages are the primary sources of disagreement, and other deviations resulting from seasonal biases in the irradiation models and one axis tracking issues are discussed in detail.

  17. Modeling Cytoskeletal Active Matter Systems

    Science.gov (United States)

    Blackwell, Robert

    Active networks of filamentous proteins and crosslinking motor proteins play a critical role in many important cellular processes. One of the most important microtubule-motor protein assemblies is the mitotic spindle, a self-organized active liquid-crystalline structure that forms during cell division and that ultimately separates chromosomes into two daughter cells. Although the spindle has been intensively studied for decades, the physical principles that govern its self-organization and function remain mysterious. To evolve a better understanding of spindle formation, structure, and dynamics, I investigate course-grained models of active liquid-crystalline networks composed of microtubules, modeled as hard spherocylinders, in diffusive equilibrium with a reservoir of active crosslinks, modeled as hookean springs that can adsorb to microtubules and and translocate at finite velocity along the microtubule axis. This model is investigated using a combination of brownian dynamics and kinetic monte carlo simulation. I have further refined this model to simulate spindle formation and kinetochore capture in the fission yeast S. pombe. I then make predictions for experimentally realizable perturbations in motor protein presence and function in S. pombe.

  18. Systemic change increases model projection uncertainty

    NARCIS (Netherlands)

    Verstegen, Judith; Karssenberg, Derek; van der Hilst, Floortje; Faaij, André

    2014-01-01

    Most spatio-temporal models are based on the assumption that the relationship between system state change and its explanatory processes is stationary. This means that model structure and parameterization are usually kept constant over time, ignoring potential systemic changes in this relationship re

  19. Dynamic modeling of the INAPRO aquaponic system

    NARCIS (Netherlands)

    Karimanzira, Divas; Keesman, Karel J.; Kloas, Werner; Baganz, Daniela; Rauschenbach, Thomas

    2016-01-01

    The use of modeling techniques to analyze aquaponics systems is demonstrated with an example of dynamic modeling for the production of Nile tilapia (Oreochromis niloticus) and tomatoes (Solanum lycopersicon) using the innovative double recirculating aquaponic system ASTAF-PRO. For the management and

  20. Modeling complex work systems - method meets reality

    NARCIS (Netherlands)

    van der Veer, Gerrit C.; Hoeve, Machteld; Lenting, Bert

    1996-01-01

    Modeling an existing task situation is often a first phase in the (re)design of information systems. For complex systems design, this model should consider both the people and the organization involved, the work, and situational aspects. Groupware Task Analysis (GTA) as part of a method for the

  1. Modeling complex work systems - method meets reality

    NARCIS (Netherlands)

    Veer, van der Gerrit C.; Hoeve, Machteld; Lenting, Bert F.

    1996-01-01

    Modeling an existing task situation is often a first phase in the (re)design of information systems. For complex systems design, this model should consider both the people and the organization involved, the work, and situational aspects. Groupware Task Analysis (GTA) as part of a method for the desi

  2. System dynamics modelling of situation awareness

    CSIR Research Space (South Africa)

    Oosthuizen, R

    2015-11-01

    Full Text Available . The feedback loops and delays in the Command and Control system also contribute to the complex dynamic behavior. This paper will build on existing situation awareness models to develop a System Dynamics model to support a qualitative investigation through...

  3. Statistical Model Checking for Stochastic Hybrid Systems

    DEFF Research Database (Denmark)

    David, Alexandre; Du, Dehui; Larsen, Kim Guldstrand

    2012-01-01

    This paper presents novel extensions and applications of the UPPAAL-SMC model checker. The extensions allow for statistical model checking of stochastic hybrid systems. We show how our race-based stochastic semantics extends to networks of hybrid systems, and indicate the integration technique ap...

  4. Models of the venous system

    DEFF Research Database (Denmark)

    Mehlsen, J

    2000-01-01

    Cardiac output is largely controlled by venous return, the driving force of which is the energy remaining at the postcapillary venous site. This force is influenced by forces acting close to the right atrium, and internally or externally upon the veins along their course. Analogue models....... The venous capacitance is also non-linear, but may be considered linear under certain conditions. The models have to include time varying pressure sources created by respiration and skeletal muscles, and if the description includes the upright position, the partly unidirectional flow through the venous...

  5. Systematic modelling and simulation of refrigeration systems

    DEFF Research Database (Denmark)

    Rasmussen, Bjarne D.; Jakobsen, Arne

    1998-01-01

    The task of developing a simulation model of a refrigeration system can be very difficult and time consuming. In order for this process to be effective, a systematic method for developing the system model is required. This method should aim at guiding the developer to clarify the purpose of the s......The task of developing a simulation model of a refrigeration system can be very difficult and time consuming. In order for this process to be effective, a systematic method for developing the system model is required. This method should aim at guiding the developer to clarify the purpose...... of the simulation, to select appropriate component models and to set up the equations in a well-arranged way. In this paper the outline of such a method is proposed and examples showing the use of this method for simulation of refrigeration systems are given....

  6. Heating, ventilation and air conditioning system modelling

    Energy Technology Data Exchange (ETDEWEB)

    Whalley, R.; Abdul-Ameer, A. [British University in Dubai (United Arab Emirates)

    2011-03-15

    Heating, ventilation and air conditioning modelling methods, for large scale, spatially dispersed systems are considered. Existing techniques are discussed and proposals for the application of novel analysis approaches are outlined. The use of distributed-lumped parameter procedures enabling the incorporation of the relatively concentrated and significantly dispersed, system element characteristics, is advocated. A dynamic model for a heating, ventilation and air conditioning system comprising inlet and exhaust fans, with air recirculation, heating/cooling and filtration units is presented. Pressure, airflow and temperature predictions within the system are computed following input, disturbance changes and purging operations. The generalised modelling advancements adopted and the applicability of the model for heating, ventilation and air conditioning system simulation, re-configuration and diagnostics is emphasised. The employment of the model for automatic, multivariable controller design purposes is commented upon. (author)

  7. Model Driven Development of Data Sensitive Systems

    DEFF Research Database (Denmark)

    Olsen, Petur

    2014-01-01

    Model-driven development strives to use formal artifacts during the development process. Formal artifacts enables automatic analyses of some aspects of the system under development. This serves to increase the understanding of the (intended) behavior of the system as well as increasing error...... detection and pushing error detection to earlier stages of development. The complexity of modeling and the size of systems which can be analyzed is severely limited when introducing data variables. The state space grows exponentially in the number of variable and the domain size of the variables...... to the values of variables. This theses strives to improve model-driven development of such data-sensitive systems. This is done by addressing three research questions. In the first we combine state-based modeling and abstract interpretation, in order to ease modeling of data-sensitive systems, while allowing...

  8. Modeling and analysis of stochastic systems

    CERN Document Server

    Kulkarni, Vidyadhar G

    2011-01-01

    Based on the author's more than 25 years of teaching experience, Modeling and Analysis of Stochastic Systems, Second Edition covers the most important classes of stochastic processes used in the modeling of diverse systems, from supply chains and inventory systems to genetics and biological systems. For each class of stochastic process, the text includes its definition, characterization, applications, transient and limiting behavior, first passage times, and cost/reward models. Along with reorganizing the material, this edition revises and adds new exercises and examples. New to the second edi

  9. System Convergence in Transport Modelling

    DEFF Research Database (Denmark)

    Rich, Jeppe; Nielsen, Otto Anker; Cantarella, Guilio E.

    2010-01-01

    -of-successive-averages (MSA) have been proposed. Convergence of the MSA under fairly weak regularity conditions was shown in Robbins and Monro (1951). The iteration between demand and assignment ? the external equilibrium ? are in many models either decoupled or follow a very simple iteration pattern. However, as demand...

  10. Models of the venous system

    DEFF Research Database (Denmark)

    Mehlsen, J

    2000-01-01

    . The venous capacitance is also non-linear, but may be considered linear under certain conditions. The models have to include time varying pressure sources created by respiration and skeletal muscles, and if the description includes the upright position, the partly unidirectional flow through the venous...

  11. Systems Engineering Model for ART Energy Conversion

    Energy Technology Data Exchange (ETDEWEB)

    Mendez Cruz, Carmen Margarita [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Rochau, Gary E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Wilson, Mollye C. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-02-01

    The near-term objective of the EC team is to establish an operating, commercially scalable Recompression Closed Brayton Cycle (RCBC) to be constructed for the NE - STEP demonstration system (demo) with the lowest risk possible. A systems engineering approach is recommended to ensure adequate requirements gathering, documentation, and mode ling that supports technology development relevant to advanced reactors while supporting crosscut interests in potential applications. A holistic systems engineering model was designed for the ART Energy Conversion program by leveraging Concurrent Engineering, Balance Model, Simplified V Model, and Project Management principles. The resulting model supports the identification and validation of lifecycle Brayton systems requirements, and allows designers to detail system-specific components relevant to the current stage in the lifecycle, while maintaining a holistic view of all system elements.

  12. Building multivariate systems biology models

    NARCIS (Netherlands)

    Kirwan, G.M.; Johansson, E.; Kleemann, R.; Verheij, E.R.; Wheelock, A.M.; Goto, S.; Trygg, J.; Wheelock, C.E.

    2012-01-01

    Systems biology methods using large-scale "omics" data sets face unique challenges: integrating and analyzing near limitless data space, while recognizing and removing systematic variation or noise. Herein we propose a complementary multivariate analysis workflow to both integrate "omics" data from

  13. Models of complex attitude systems

    DEFF Research Database (Denmark)

    Sørensen, Bjarne Taulo

    production, food and the environment, technological progress, animal welfare, local employment and the local economy. In addition, the survey included a conjoint task by which participants’ evaluations of the importance of production system attributes were measured. The data were analysed by means of causal...

  14. Adsorption Rate Models for Multicomponent Adsorption Systems

    Institute of Scientific and Technical Information of China (English)

    姚春才

    2004-01-01

    Three adsorption rate models are derived for multicomponent adsorption systems under either pore diffusion or surface diffusion control. The linear driving force (LDF) model is obtained by assuming a parabolic intraparticle concentration profile. Models I and Ⅱ are obtained from the parabolic concentration layer approximation. Examples are presented to demonstrate the usage and accuracy of these models. It is shown that Model I is suitable for batch adsorption calculations and Model Ⅱ provides a good approximation in fixed-bed adsorption processes while the LDF model should not be used in batch adsorption and may be considered acceptable in fixed-bed adsorption where the parameter Ti is relatively large.

  15. Modeling approach suitable for energy system

    Energy Technology Data Exchange (ETDEWEB)

    Goetschel, D. V.

    1979-01-01

    Recently increased attention has been placed on optimization problems related to the determination and analysis of operating strategies for energy systems. Presented in this paper is a nonlinear model that can be used in the formulation of certain energy-conversion systems-modeling problems. The model lends itself nicely to solution approaches based on nonlinear-programming algorithms and, in particular, to those methods falling into the class of variable metric algorithms for nonlinearly constrained optimization.

  16. Development and application of earth system models

    OpenAIRE

    Prinn, Ronald G.

    2012-01-01

    The global environment is a complex and dynamic system. Earth system modeling is needed to help understand changes in interacting subsystems, elucidate the influence of human activities, and explore possible future changes. Integrated assessment of environment and human development is arguably the most difficult and most important “systems” problem faced. To illustrate this approach, we present results from the integrated global system model (IGSM), which consists of coupled submodels address...

  17. Statistical Model Checking for Stochastic Hybrid Systems

    DEFF Research Database (Denmark)

    David, Alexandre; Du, Dehui; Larsen, Kim Guldstrand

    2012-01-01

    This paper presents novel extensions and applications of the UPPAAL-SMC model checker. The extensions allow for statistical model checking of stochastic hybrid systems. We show how our race-based stochastic semantics extends to networks of hybrid systems, and indicate the integration technique...... applied for implementing this semantics in the UPPAAL-SMC simulation engine. We report on two applications of the resulting tool-set coming from systems biology and energy aware buildings....

  18. A model for international border management systems.

    Energy Technology Data Exchange (ETDEWEB)

    Duggan, Ruth Ann

    2008-09-01

    To effectively manage the security or control of its borders, a country must understand its border management activities as a system. Using its systems engineering and security foundations as a Department of Energy National Security Laboratory, Sandia National Laboratories has developed such an approach to modeling and analyzing border management systems. This paper describes the basic model and its elements developed under Laboratory Directed Research and Development project 08-684.

  19. A Conceptual Data Model of Datum Systems

    Science.gov (United States)

    McCaleb, Michael R.

    1999-01-01

    A new conceptual data model that addresses the geometric dimensioning and tolerancing concepts of datum systems, datums, datum features, datum targets, and the relationships among these concepts, is presented. Additionally, a portion of a related data model, Part 47 of STEP (ISO 10303-47), is reviewed and a comparison is made between it and the new conceptual data model.

  20. Modelling of Generic Slung Load System

    DEFF Research Database (Denmark)

    Bisgaard, Morten; Bendtsen, Jan Dimon; La Cour-Harbo, Anders

    2006-01-01

    This paper presents the result of modelling and verification of a generic slung load system using a small-scale helicopter. The model is intended for use in simulation, pilot training, estimation, and control. The model is derived using a redundant coordinate formulation based on Gauss Principle ...

  1. Human performance modeling for system of systems analytics.

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, Kevin R.; Lawton, Craig R.; Basilico, Justin Derrick; Longsine, Dennis E. (INTERA, Inc., Austin, TX); Forsythe, James Chris; Gauthier, John Henry; Le, Hai D.

    2008-10-01

    A Laboratory-Directed Research and Development project was initiated in 2005 to investigate Human Performance Modeling in a System of Systems analytic environment. SAND2006-6569 and SAND2006-7911 document interim results from this effort; this report documents the final results. The problem is difficult because of the number of humans involved in a System of Systems environment and the generally poorly defined nature of the tasks that each human must perform. A two-pronged strategy was followed: one prong was to develop human models using a probability-based method similar to that first developed for relatively well-understood probability based performance modeling; another prong was to investigate more state-of-art human cognition models. The probability-based modeling resulted in a comprehensive addition of human-modeling capability to the existing SoSAT computer program. The cognitive modeling resulted in an increased understanding of what is necessary to incorporate cognition-based models to a System of Systems analytic environment.

  2. Complex system modelling for veterinary epidemiology.

    Science.gov (United States)

    Lanzas, Cristina; Chen, Shi

    2015-02-01

    The use of mathematical models has a long tradition in infectious disease epidemiology. The nonlinear dynamics and complexity of pathogen transmission pose challenges in understanding its key determinants, in identifying critical points, and designing effective mitigation strategies. Mathematical modelling provides tools to explicitly represent the variability, interconnectedness, and complexity of systems, and has contributed to numerous insights and theoretical advances in disease transmission, as well as to changes in public policy, health practice, and management. In recent years, our modelling toolbox has considerably expanded due to the advancements in computing power and the need to model novel data generated by technologies such as proximity loggers and global positioning systems. In this review, we discuss the principles, advantages, and challenges associated with the most recent modelling approaches used in systems science, the interdisciplinary study of complex systems, including agent-based, network and compartmental modelling. Agent-based modelling is a powerful simulation technique that considers the individual behaviours of system components by defining a set of rules that govern how individuals ("agents") within given populations interact with one another and the environment. Agent-based models have become a recent popular choice in epidemiology to model hierarchical systems and address complex spatio-temporal dynamics because of their ability to integrate multiple scales and datasets.

  3. Using Interaction Scenarios to Model Information Systems

    DEFF Research Database (Denmark)

    Bækgaard, Lars; Bøgh Andersen, Peter

    The purpose of this paper is to define and discuss a set of interaction primitives that can be used to model the dynamics of socio-technical activity systems, including information systems, in a way that emphasizes structural aspects of the interaction that occurs in such systems. The primitives...

  4. Port-based modeling of mechatronic systems

    NARCIS (Netherlands)

    Breedveld, Peter C.

    2004-01-01

    Many engineering activities, including mechatronic design, require that a multidomain or ‘multi-physics’ system and its control system be designed as an integrated system. This contribution discusses the background and tools for a port-based approach to integrated modeling and simulation of physical

  5. 离子液体[C4mim][PF6]与N,N-二甲基甲酰胺二元混合物在298.15 K~318.15 K的密度和粘度%Densities and Viscosities of the Ionic Liquid [C4mim][PF6]+N,N-dimethylformamide Binary Mixtures at 293.15 K to 318.15 K

    Institute of Scientific and Technical Information of China (English)

    耿彦芳; 王腾芳; 虞大红; 彭昌军; 刘洪来; 胡英

    2008-01-01

    Viscosities and densities for 1-butyl-3-methylimidazolium hexafluorophosphate ([C4mim][PF6]) and N,N-dimethylformamide (DMF) binary mixtures have been measured at the temperature range from 293.15 K to 318.15 K. It is shown that the viscosities and densities decrease monotonously with temperature and the content of DME Various correlation methods including Arrhenius-like equation, Seddon et al.'s equation, Redlich-Kister equation with four parameters, and other empirical equations were applied to evaluate these experimental data. A model based on an equation of state for estimating the viscosity of mixtures containing ionic liquids were proposed by coupling with the excess Gibbs free energy model of viscosity, which can synchronously calculate the viscosity and the molar volume. The results show that the model gives a deviation of 8.29% for the viscosity, and a deviation of 1.05% for the molar volume when only one temperature-independent adjustable parameter is adopted. The cor-relation accuracy is further improved when two parameters or one temperature-dependent parameter is used.

  6. Lattice models of ionic systems

    Science.gov (United States)

    Kobelev, Vladimir; Kolomeisky, Anatoly B.; Fisher, Michael E.

    2002-05-01

    A theoretical analysis of Coulomb systems on lattices in general dimensions is presented. The thermodynamics is developed using Debye-Hückel theory with ion-pairing and dipole-ion solvation, specific calculations being performed for three-dimensional lattices. As for continuum electrolytes, low-density results for simple cubic (sc), body-centered cubic (bcc), and face-centered cubic (fcc) lattices indicate the existence of gas-liquid phase separation. The predicted critical densities have values comparable to those of continuum ionic systems, while the critical temperatures are 60%-70% higher. However, when the possibility of sublattice ordering as well as Debye screening is taken into account systematically, order-disorder transitions and a tricritical point are found on sc and bcc lattices, and gas-liquid coexistence is suppressed. Our results agree with recent Monte Carlo simulations of lattice electrolytes.

  7. Mindfulness in Motion (MIM): An Onsite Mindfulness Based Intervention (MBI) for Chronically High Stress Work Environments to Increase Resiliency and Work Engagement.

    Science.gov (United States)

    Klatt, Maryanna; Steinberg, Beth; Duchemin, Anne-Marie

    2015-07-01

    A pragmatic mindfulness intervention to benefit personnel working in chronically high-stress environments, delivered onsite during the workday, is timely and valuable to employee and employer alike. Mindfulness in Motion (MIM) is a Mindfulness Based Intervention (MBI) offered as a modified, less time intensive method (compared to Mindfulness-Based Stress Reduction), delivered onsite, during work, and intends to enable busy working adults to experience the benefits of mindfulness. It teaches mindful awareness principles, rehearses mindfulness as a group, emphasizes the use of gentle yoga stretches, and utilizes relaxing music in the background of both the group sessions and individual mindfulness practice. MIM is delivered in a group format, for 1 hr/week/8 weeks. CDs and a DVD are provided to facilitate individual practice. The yoga movement is emphasized in the protocol to facilitate a quieting of the mind. The music is included for participants to associate the relaxed state experienced in the group session with their individual practice. To determine the intervention feasibility/efficacy we conducted a randomized wait-list control group in Intensive Care Units (ICUs). ICUs represent a high-stress work environment where personnel experience chronic exposure to catastrophic situations as they care for seriously injured/ill patients. Despite high levels of work-related stress, few interventions have been developed and delivered onsite for such environments. The intervention is delivered on site in the ICU, during work hours, with participants receiving time release to attend sessions. The intervention is well received with 97% retention rate. Work engagement and resiliency increase significantly in the intervention group, compared to the wait-list control group, while participant respiration rates decrease significantly pre-post in 6/8 of the weekly sessions. Participants value institutional support, relaxing music, and the instructor as pivotal to program success

  8. Quantitative Models and Analysis for Reactive Systems

    DEFF Research Database (Denmark)

    Thrane, Claus

    phones and websites. Acknowledging that now more than ever, systems come in contact with the physical world, we need to revise the way we construct models and verification algorithms, to take into account the behavior of systems in the presence of approximate, or quantitative information, provided...... by the environment in which they are embedded. This thesis studies the semantics and properties of a model-based framework for re- active systems, in which models and specifications are assumed to contain quantifiable information, such as references to time or energy. Our goal is to develop a theory of approximation......, by studying how small changes to our models affect the verification results. A key source of motivation for this work can be found in The Embedded Systems Design Challenge [HS06] posed by Thomas A. Henzinger and Joseph Sifakis. It contains a call for advances in the state-of-the-art of systems verification...

  9. Simulation Model of Brushless Excitation System

    Directory of Open Access Journals (Sweden)

    Ahmed N.A.  Alla

    2007-01-01

    Full Text Available Excitation system is key element in the dynamic performance of electric power systems, accurate excitation models are of great importance in simulating and investigating the power system transient phenomena. Parameter identification of the Brushless excitation system was presented. First a block diagram for the EXS parameter was proposed based on the documents and maps in the power station. To identify the parameters of this model, a test procedure to obtain step response, was presented. Using the Genetic Algorithm with the Matlab-software it was possible to identify all the necessary parameters of the model. Using the same measured input signals the response from the standard model showed nearly the same behavior as the excitation system.

  10. Mechatronic Systems Design Methods, Models, Concepts

    CERN Document Server

    Janschek, Klaus

    2012-01-01

    In this textbook, fundamental methods for model-based design of mechatronic systems are presented in a systematic, comprehensive form. The method framework presented here comprises domain-neutral methods for modeling and performance analysis: multi-domain modeling (energy/port/signal-based), simulation (ODE/DAE/hybrid systems), robust control methods, stochastic dynamic analysis, and quantitative evaluation of designs using system budgets. The model framework is composed of analytical dynamic models for important physical and technical domains of realization of mechatronic functions, such as multibody dynamics, digital information processing and electromechanical transducers. Building on the modeling concept of a technology-independent generic mechatronic transducer, concrete formulations for electrostatic, piezoelectric, electromagnetic, and electrodynamic transducers are presented. More than 50 fully worked out design examples clearly illustrate these methods and concepts and enable independent study of th...

  11. Improvements in continuum modeling for biomolecular systems

    CERN Document Server

    Qiao, Yu

    2015-01-01

    Modeling of biomolecular systems plays an essential role in understanding biological processes, such as ionic flow across channels, protein modification or interaction, and cell signaling. The continuum model described by the Poisson-Boltzmann (PB)/Poisson-Nernst-Planck (PNP) equations has made great contributions towards simulation of these processes. However, the model has shortcomings in its commonly used form and cannot capture (or cannot accurately capture) some important physical properties of biological systems. Considerable efforts have been made to improve the continuum model to account for discrete particle interactions and to make progress in numerical methods to provide accurate and efficient simulation. This review will summarize recent main improvements in continuum modeling for biomolecular systems, with focus on the size-modified models, the coupling of the classical density functional theory and PNP equations, the coupling of polar and nonpolar interactions, and numerical progress.

  12. Structural system identification: Structural dynamics model validation

    Energy Technology Data Exchange (ETDEWEB)

    Red-Horse, J.R.

    1997-04-01

    Structural system identification is concerned with the development of systematic procedures and tools for developing predictive analytical models based on a physical structure`s dynamic response characteristics. It is a multidisciplinary process that involves the ability (1) to define high fidelity physics-based analysis models, (2) to acquire accurate test-derived information for physical specimens using diagnostic experiments, (3) to validate the numerical simulation model by reconciling differences that inevitably exist between the analysis model and the experimental data, and (4) to quantify uncertainties in the final system models and subsequent numerical simulations. The goal of this project was to develop structural system identification techniques and software suitable for both research and production applications in code and model validation.

  13. FSM Model of a Simple Photovoltaic System

    Directory of Open Access Journals (Sweden)

    Martina Latkova

    2015-01-01

    Full Text Available The paper describes a simulation model of a simple photovoltaic system intended as a tool for testing the use of finite state machines for simulations representing a long-term operation of renewable energy sources. The mathematical model of the photovoltaic system is described first. Then it is used to build a finite state machine model that calculates a power output of the photovoltaic system for changing values of a solar irradiance and a temperature. Data measured on a real photovoltaic installation are used to verify model’s accuracy through its comparison with a previously created and verified Matlab model. The finite state machine model presented in this paper was created using Ptolemy II software.

  14. Simulation-based Manufacturing System Modeling

    Institute of Scientific and Technical Information of China (English)

    卫东; 金烨; 范秀敏; 严隽琪

    2003-01-01

    In recent years, computer simulation appears to be very advantageous technique for researching the resource-constrained manufacturing system. This paper presents an object-oriented simulation modeling method, which combines the merits of traditional methods such as IDEF0 and Petri Net. In this paper, a four-layer-one-angel hierarchical modeling framework based on OOP is defined. And the modeling description of these layers is expounded, such as: hybrid production control modeling and human resource dispatch modeling. To validate the modeling method, a case study of an auto-product line in a motor manufacturing company has been carried out.

  15. Modelling of Generic Slung Load System

    DEFF Research Database (Denmark)

    Bisgaard, Morten; Bendtsen, Jan Dimon; La Cour-Harbo, Anders

    2006-01-01

    of Least Constraint using the Udwadia-Kalaba equation and can be used to model all body to body slung load suspension types. The model gives an intuitive and easy-to-use way of modelling and simulating di erent slung load suspension types and it includes detection and response of wire slacking......This paper presents the result of modelling and verification of a generic slung load system using a small-scale helicopter. The model is intended for use in simulation, pilot training, estimation, and control. The model is derived using a redundant coordinate formulation based on Gauss Principle...

  16. HVDC System Characteristics and Simulation Models

    Energy Technology Data Exchange (ETDEWEB)

    Moon, S.I.; Han, B.M.; Jang, G.S. [Electric Enginnering and Science Research Institute, Seoul (Korea)

    2001-07-01

    This report deals with the AC-DC power system simulation method by PSS/E and EUROSTAG for the development of a strategy for the reliable operation of the Cheju-Haenam interconnected system. The simulation using both programs is performed to analyze HVDC simulation models. In addition, the control characteristics of the Cheju-Haenam HVDC system as well as Cheju AC system characteristics are described in this work. (author). 104 figs., 8 tabs.

  17. La filogénesis humana según la teoría mimética de René Girard

    OpenAIRE

    Moreno Fernandéz, Agustín

    2015-01-01

    La teoría mimética de René Girard contiene una interpretación acerca del origen de la especie humana y el proceso de hominización. Su propuesta destaca por el afán de aunar las aportaciones de la etología animal y de la antropología cultural, en torno al mimetismo y su hipótesis del mecanismo del chivo expiatorio. Nuestro objetivo es presentar una síntesis de sus consideraciones acerca de la antropogénesis, presentes a lo largo de su obra.

  18. Modeling the Dynamics of an Information System

    Directory of Open Access Journals (Sweden)

    Jacek Unold

    2003-11-01

    Full Text Available The article concentrates on the nature of a social subsystem of an information system. It analyzes the nature of information processes of collectivity within an IS and introduces a model of IS dynamics. The model is based on the assumption that a social subsystem of an information system works as a nonlinear dynamic system. The model of IS dynamics is verified on the indexes of the stock market. It arises from the basic assumption of the technical analysis of the markets, that is, the index chart reflects the play of demand and supply, which in turn represents the crowd sentiment on the market.

  19. Systematic modelling and simulation of refrigeration systems

    DEFF Research Database (Denmark)

    Rasmussen, Bjarne D.; Jakobsen, Arne

    1998-01-01

    The task of developing a simulation model of a refrigeration system can be very difficult and time consuming. In order for this process to be effective, a systematic method for developing the system model is required. This method should aim at guiding the developer to clarify the purpose...... of the simulation, to select appropriate component models and to set up the equations in a well-arranged way. In this paper the outline of such a method is proposed and examples showing the use of this method for simulation of refrigeration systems are given....

  20. MODEL DRIVEN DEVELOPMENT OF ONLINE BANKING SYSTEMS

    Directory of Open Access Journals (Sweden)

    Bresfelean Vasile Paul

    2011-07-01

    Full Text Available In case of online applications the cycle of software development varies from the routine. The online environment, the variety of users, the treatability of the mass of information created by them, the reusability and the accessibility from different devices are all factors of these systems complexity. The use of model drive approach brings several advantages that ease up the development process. Working prototypes that simplify client relationship and serve as the base of model tests can be easily made from models describing the system. These systems make possible for the banks clients to make their desired actions from anywhere. The user has the possibility of accessing information or making transactions.

  1. Development and Integration of Control System Models

    Science.gov (United States)

    Kim, Young K.

    1998-01-01

    The computer simulation tool, TREETOPS, has been upgraded and used at NASA/MSFC to model various complicated mechanical systems and to perform their dynamics and control analysis with pointing control systems. A TREETOPS model of Advanced X-ray Astrophysics Facility - Imaging (AXAF-1) dynamics and control system was developed to evaluate the AXAF-I pointing performance for Normal Pointing Mode. An optical model of Shooting Star Experiment (SSE) was also developed and its optical performance analysis was done using the MACOS software.

  2. Ionic liquid-in-oil microemulsions composed of double chain surface active ionic liquid as a surfactant: temperature dependent solvent and rotational relaxation dynamics of coumarin-153 in [Py][TF2N]/[C4mim][AOT]/benzene microemulsions.

    Science.gov (United States)

    Rao, Vishal Govind; Mandal, Sarthak; Ghosh, Surajit; Banerjee, Chiranjib; Sarkar, Nilmoni

    2012-07-19

    In the recent past, nonaqueous microemulsions containing ionic liquids (ILs) have been utilized for performing chemical reactions, preparation of nanomaterials, and synthesis of nanostructured polymers and in drug delivery systems. The most promising fact about IL-in-oil microemulsions is their high thermal stability compared to that of aqueous microemulsions. In our earlier publication (Rao, V. G.; Ghosh, S.; Ghatak, C.; Mandal, S.; Brahmachari, U.; Sarkar, N. J. Phys. Chem. B 2012, 116, 2850-2855), we presented for the first time the possibility of creating huge number of IL-in-oil microemulsions, just by replacing the inorganic cation, Na(+), of NaAOT by any organic cation and using different ionic liquids as the polar core. In this manuscript we are interested in exploring the effect of temperature on such systems. We have characterized the phase diagram of the [Py][TF2N]/[C4mim][AOT]/benzene ternary system at 298 K. We have shown that in the experimental temperature range employed in this study, the microemulsions remain stable and a slight decrease in the size of the microemulsions is observed with increasing temperature. We have reported the detailed study of solvent and rotational relaxation of coumarin 153 (C-153) in neat IL, N-methyl-N-propylpyrrolidinium bis((trifluoromethyl)sulfonyl)imide ([Py][TF2N]), and in [Py][TF2N]/[C4mim][AOT]/benzene microemulsions using steady state and picosecond time-resolved spectroscopy. We have monitored the effect of (i) varying the [Py][TF2N]/[C4mim][AOT] molar ratio (R value) and (ii) temperature on solvent and rotational relaxation of C-153. The features observed in absorption and emission spectra clearly indicate that (i) the probe molecules reside at the polar interfacial region of the [Py][TF2N]/[C4mim][AOT]/benzene microemulsions and (ii) with increasing R value the probe molecules move toward the polar IL-pool of the microemulsion. We have shown that the increase in solvation time on going from neat [Py][TF2N] to

  3. Models for the study of whole systems.

    Science.gov (United States)

    Bell, Iris R; Koithan, Mary

    2006-12-01

    This article summarizes a network and complex systems science model for research on whole systems of complementary and alternative medicine (CAM) such as homeopathy and traditional Chinese medicine. The holistic concepts of networks and nonlinear dynamical complex systems are well matched to the global and interactive perspectives of whole systems of CAM, whereas the reductionistic science model is well matched to the isolated local organ, cell, and molecular mechanistic perspectives of pharmaceutically based biomedicine. Whole systems of CAM are not drugs with specific actions. The diagnostic and therapeutic approaches of whole systems of CAM produce effects that involve global and patterned shifts across multiple subsystems of the person as a whole. For homeopathy, several characteristics of complex systems, including the probabilistic nature of attractor patterns, variable sensitivity of complex systems to initial conditions, and emergent behaviors in the evolution of a system in its full environmental context over time, could help account for the mixed basic science and controlled clinical trial research findings, in contrast with the consistently positive outcomes of observational studies in the literature. Application of theories and methods from complex systems and network science can open a new era of advances in understanding factors that lead to good versus poor individual global outcome patterns and to rational triage of patients to one type of care over another. The growing reliance on complex systems thinking and systems biology for cancer research affords a unique opportunity to bridge between the CAM and conventional medical worlds with some common language and conceptual models.

  4. Use of an operational model evaluation system for model intercomparison

    Energy Technology Data Exchange (ETDEWEB)

    Foster, K. T., LLNL

    1998-03-01

    The Atmospheric Release Advisory Capability (ARAC) is a centralized emergency response system used to assess the impact from atmospheric releases of hazardous materials. As part of an on- going development program, new three-dimensional diagnostic windfield and Lagrangian particle dispersion models will soon replace ARAC`s current operational windfield and dispersion codes. A prototype model performance evaluation system has been implemented to facilitate the study of the capabilities and performance of early development versions of these new models relative to ARAC`s current operational codes. This system provides tools for both objective statistical analysis using common performance measures and for more subjective visualization of the temporal and spatial relationships of model results relative to field measurements. Supporting this system is a database of processed field experiment data (source terms and meteorological and tracer measurements) from over 100 individual tracer releases.

  5. Evaluation of SystemC Modelling of Reconfigurable Embedded Systems

    CERN Document Server

    Rissa, Tero; Luk, Wayne

    2011-01-01

    This paper evaluates the use of pin and cycle accurate SystemC models for embedded system design exploration and early software development. The target system is MicroBlaze VanillaNet Platform running MicroBlaze uClinux operating system. The paper compares Register Transfer Level (RTL) Hardware Description Language (HDL) simulation speed to the simulation speed of several different SystemC models. It is shown that simulation speed of pin and cycle accurate models can go up to 150 kHz, compared to 100 Hz range of HDL simulation. Furthermore, utilising techniques that temporarily compromise cycle accuracy, effective simulation speed of up to 500 kHz can be obtained.

  6. Demonstration of 6DOF Arc-mim/mm Control in the FCT Using Proba-3 Metrology and Control System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Implement in FCT avionics and attitude control architecture and software that enables order of magnitude increase in control capability for next-generation formation...

  7. Modeling of Generic Slung Load System

    DEFF Research Database (Denmark)

    Bisgaard, Morten; Bendtsen, Jan Dimon; la Cour-Harbo, Anders

    2009-01-01

    This paper presents the result of the modelling and verification of a generic slung load system using a small-scale helicopter. The model is intended for use in simulation, pilot training, estimation, and control. The model is derived using a redundant coordinate formulation based on Gauss......' Principle of Least Constraint using the Udwadia-Kalaba equation and can be used to model all body to body slung load suspension types. The model provides intuitive and easy-to-use means of modelling and simulating different slung load suspension types. It includes detection of, and response to, wire...... slackening and tightening as well as aerodynamic coupling between the helicopter and the load. Furthermore, it is shown how the model can be easily used for multi-lift systems either with multiple helicopters or multiple loads. A numerical stabilisation algorithm is introduced and finally the use...

  8. Systems Evaluation Methods, Models, and Applications

    CERN Document Server

    Liu, Siefeng; Xie, Naiming; Yuan, Chaoqing

    2011-01-01

    A book in the Systems Evaluation, Prediction, and Decision-Making Series, Systems Evaluation: Methods, Models, and Applications covers the evolutionary course of systems evaluation methods, clearly and concisely. Outlining a wide range of methods and models, it begins by examining the method of qualitative assessment. Next, it describes the process and methods for building an index system of evaluation and considers the compared evaluation and the logical framework approach, analytic hierarchy process (AHP), and the data envelopment analysis (DEA) relative efficiency evaluation method. Unique

  9. Analytical performance modeling for computer systems

    CERN Document Server

    Tay, Y C

    2013-01-01

    This book is an introduction to analytical performance modeling for computer systems, i.e., writing equations to describe their performance behavior. It is accessible to readers who have taken college-level courses in calculus and probability, networking and operating systems. This is not a training manual for becoming an expert performance analyst. Rather, the objective is to help the reader construct simple models for analyzing and understanding the systems that they are interested in.Describing a complicated system abstractly with mathematical equations requires a careful choice of assumpti

  10. Modeling the variation trends of glacier systems

    Directory of Open Access Journals (Sweden)

    Z. Xie

    2013-01-01

    Full Text Available The basic principles and methods for a functional glacier systems model are introduced and applied for glaciers of Northwest China. When running the model we assume that a glacier system is under steady state conditions in the initial year. The median size of a glacier system is used as representative for the system. The curve of glacier area distribution against elevation is used to compute the increase in equilibrium line altitude (ELA, and the annual glacier ablation is calculated using a global formula a = 1.33(9.66 + ts².⁸⁵ [4, p. 96]. The net mass balance near the ELA under steady state conditions represents the net mass balance of the whole glacier system, and the time required for glacier runoff to return to the initial year level is calculated according to the law of glacier runoff variation, and used to calculate the variation of glacier area. The variation of glacier runoff is modeled according to ablation at the ELA, and the variation of glacier volume is modeled according to the absolute value of the mass balance. The observed changes in surveyed glaciers in China over recent decades were broadly consistent with predictions of the glacier system model. The model therefore offers a reliable method for the prediction of changes in glacier systems in response to changing climate.

  11. Photovoltaic System Modeling. Uncertainty and Sensitivity Analyses

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Clifford W. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Martin, Curtis E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-08-01

    We report an uncertainty and sensitivity analysis for modeling AC energy from ph otovoltaic systems . Output from a PV system is predicted by a sequence of models. We quantify u ncertainty i n the output of each model using empirical distribution s of each model's residuals. We propagate uncertainty through the sequence of models by sampli ng these distributions to obtain a n empirical distribution of a PV system's output. We consider models that: (1) translate measured global horizontal, direct and global diffuse irradiance to plane - of - array irradiance; (2) estimate effective irradiance; (3) predict cell temperature; (4) estimate DC voltage, current and power ; (5) reduce DC power for losses due to inefficient maximum power point tracking or mismatch among modules; and (6) convert DC to AC power . O ur analysis consider s a notional PV system com prising an array of FirstSolar FS - 387 modules and a 250 kW AC inverter ; we use measured irradiance and weather at Albuquerque, NM. We found the uncertainty in PV syste m output to be relatively small, on the order of 1% for daily energy. We found that unce rtainty in the models for POA irradiance and effective irradiance to be the dominant contributors to uncertainty in predicted daily energy. Our analysis indicates that efforts to reduce the uncertainty in PV system output predictions may yield the greatest improvements by focusing on the POA and effective irradiance models.

  12. Climate Model Diagnostic Analyzer Web Service System

    Science.gov (United States)

    Lee, S.; Pan, L.; Zhai, C.; Tang, B.; Kubar, T. L.; Li, J.; Zhang, J.; Wang, W.

    2015-12-01

    Both the National Research Council Decadal Survey and the latest Intergovernmental Panel on Climate Change Assessment Report stressed the need for the comprehensive and innovative evaluation of climate models with the synergistic use of global satellite observations in order to improve our weather and climate simulation and prediction capabilities. The abundance of satellite observations for fundamental climate parameters and the availability of coordinated model outputs from CMIP5 for the same parameters offer a great opportunity to understand and diagnose model biases in climate models. In addition, the Obs4MIPs efforts have created several key global observational datasets that are readily usable for model evaluations. However, a model diagnostic evaluation process requires physics-based multi-variable comparisons that typically involve large-volume and heterogeneous datasets, making them both computationally- and data-intensive. In response, we have developed a novel methodology to diagnose model biases in contemporary climate models and implementing the methodology as a web-service based, cloud-enabled, provenance-supported climate-model evaluation system. The evaluation system is named Climate Model Diagnostic Analyzer (CMDA), which is the product of the research and technology development investments of several current and past NASA ROSES programs. The current technologies and infrastructure of CMDA are designed and selected to address several technical challenges that the Earth science modeling and model analysis community faces in evaluating and diagnosing climate models. In particular, we have three key technology components: (1) diagnostic analysis methodology; (2) web-service based, cloud-enabled technology; (3) provenance-supported technology. The diagnostic analysis methodology includes random forest feature importance ranking, conditional probability distribution function, conditional sampling, and time-lagged correlation map. We have implemented the

  13. CTBT integrated verification system evaluation model supplement

    Energy Technology Data Exchange (ETDEWEB)

    EDENBURN,MICHAEL W.; BUNTING,MARCUS; PAYNE JR.,ARTHUR C.; TROST,LAWRENCE C.

    2000-03-02

    Sandia National Laboratories has developed a computer based model called IVSEM (Integrated Verification System Evaluation Model) to estimate the performance of a nuclear detonation monitoring system. The IVSEM project was initiated in June 1994, by Sandia's Monitoring Systems and Technology Center and has been funded by the U.S. Department of Energy's Office of Nonproliferation and National Security (DOE/NN). IVSEM is a simple, ''top-level,'' modeling tool which estimates the performance of a Comprehensive Nuclear Test Ban Treaty (CTBT) monitoring system and can help explore the impact of various sensor system concepts and technology advancements on CTBT monitoring. One of IVSEM's unique features is that it integrates results from the various CTBT sensor technologies (seismic, in sound, radionuclide, and hydroacoustic) and allows the user to investigate synergy among the technologies. Specifically, IVSEM estimates the detection effectiveness (probability of detection), location accuracy, and identification capability of the integrated system and of each technology subsystem individually. The model attempts to accurately estimate the monitoring system's performance at medium interfaces (air-land, air-water) and for some evasive testing methods such as seismic decoupling. The original IVSEM report, CTBT Integrated Verification System Evaluation Model, SAND97-25 18, described version 1.2 of IVSEM. This report describes the changes made to IVSEM version 1.2 and the addition of identification capability estimates that have been incorporated into IVSEM version 2.0.

  14. CTBT integrated verification system evaluation model supplement

    Energy Technology Data Exchange (ETDEWEB)

    EDENBURN,MICHAEL W.; BUNTING,MARCUS; PAYNE JR.,ARTHUR C.; TROST,LAWRENCE C.

    2000-03-02

    Sandia National Laboratories has developed a computer based model called IVSEM (Integrated Verification System Evaluation Model) to estimate the performance of a nuclear detonation monitoring system. The IVSEM project was initiated in June 1994, by Sandia's Monitoring Systems and Technology Center and has been funded by the U.S. Department of Energy's Office of Nonproliferation and National Security (DOE/NN). IVSEM is a simple, ''top-level,'' modeling tool which estimates the performance of a Comprehensive Nuclear Test Ban Treaty (CTBT) monitoring system and can help explore the impact of various sensor system concepts and technology advancements on CTBT monitoring. One of IVSEM's unique features is that it integrates results from the various CTBT sensor technologies (seismic, in sound, radionuclide, and hydroacoustic) and allows the user to investigate synergy among the technologies. Specifically, IVSEM estimates the detection effectiveness (probability of detection), location accuracy, and identification capability of the integrated system and of each technology subsystem individually. The model attempts to accurately estimate the monitoring system's performance at medium interfaces (air-land, air-water) and for some evasive testing methods such as seismic decoupling. The original IVSEM report, CTBT Integrated Verification System Evaluation Model, SAND97-25 18, described version 1.2 of IVSEM. This report describes the changes made to IVSEM version 1.2 and the addition of identification capability estimates that have been incorporated into IVSEM version 2.0.

  15. Model Updating Nonlinear System Identification Toolbox Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ZONA Technology proposes to develop an enhanced model updating nonlinear system identification (MUNSID) methodology by adopting the flight data with state-of-the-art...

  16. Model and method for optimizing heterogeneous systems

    Science.gov (United States)

    Antamoshkin, O. A.; Antamoshkina, O. A.; Zelenkov, P. V.; Kovalev, I. V.

    2016-11-01

    Methodology of distributed computing performance boost by reduction of delays number is proposed. Concept of n-dimentional requirements triangle is introduced. Dynamic mathematical model of resource use in distributed computing systems is described.

  17. Modelling the evolution of human trail systems

    Science.gov (United States)

    Helbing, Dirk; Keltsch, Joachim; Molnár, Péter

    1997-07-01

    Many human social phenomena, such as cooperation, the growth of settlements, traffic dynamics and pedestrian movement, appear to be accessible to mathematical descriptions that invoke self-organization. Here we develop a model of pedestrian motion to explore the evolution of trails in urban green spaces such as parks. Our aim is to address such questions as what the topological structures of these trail systems are, and whether optimal path systems can be predicted for urban planning. We use an `active walker' model that takes into account pedestrian motion and orientation and the concomitant feedbacks with the surrounding environment. Such models have previously been applied to the study of complex structure formation in physical, chemical and biological systems. We find that our model is able to reproduce many of the observed large-scale spatial features of trail systems.

  18. Power system coherency and model reduction

    CERN Document Server

    Chow, Joe H

    2014-01-01

    This book provides a comprehensive treatment for understanding interarea modes in large power systems and obtaining reduced-order models using the coherency concept and selective modal analysis method.

  19. Propulsion System Models for Rotorcraft Conceptual Design

    Science.gov (United States)

    Johnson, Wayne

    2014-01-01

    The conceptual design code NDARC (NASA Design and Analysis of Rotorcraft) was initially implemented to model conventional rotorcraft propulsion systems, consisting of turboshaft engines burning jet fuel, connected to one or more rotors through a mechanical transmission. The NDARC propulsion system representation has been extended to cover additional propulsion concepts, including electric motors and generators, rotor reaction drive, turbojet and turbofan engines, fuel cells and solar cells, batteries, and fuel (energy) used without weight change. The paper describes these propulsion system components, the architecture of their implementation in NDARC, and the form of the models for performance and weight. Requirements are defined for improved performance and weight models of the new propulsion system components. With these new propulsion models, NDARC can be used to develop environmentally-friendly rotorcraft designs.

  20. Spinal Cord Injury Model System Information Network

    Science.gov (United States)

    ... Go New to Website Managing Bowel Function After Spinal Cord Injury Resilience, Depression and Bouncing Back after SCI Getting ... the UAB-SCIMS Contact the UAB-SCIMS UAB Spinal Cord Injury Model System Newly Injured Health Daily Living Consumer ...

  1. Systemic Therapy: A New Brief Intervention Model.

    Science.gov (United States)

    Searight, H. Russell; Openlander, Patrick

    1984-01-01

    Describes a newly developing mode of problem-oriented brief therapy. The systemic therapy model emphasizes the interactional context of clients' problems and represents an efficient intervention paradigm. (Author/JAC)

  2. Computational Models for Nonlinear Aeroelastic Systems Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Clear Science Corp. and Duke University propose to develop and demonstrate a new and efficient computational method of modeling nonlinear aeroelastic systems. The...

  3. Regional Ocean Modeling System (ROMS): Samoa

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 7-day, 3-hourly forecast for the region surrounding the islands of Samoa at approximately 3-km resolution. While considerable...

  4. Regional Ocean Modeling System (ROMS): CNMI

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 7-day, 3-hourly forecast for the region surrounding the Commonwealth of the Northern Mariana Islands (CNMI) at approximately...

  5. Forecasting Models in the State Education System

    Directory of Open Access Journals (Sweden)

    Gintautas DZEMYDA

    2003-04-01

    Full Text Available This paper presents model-based assessment and forecasting of the Lithuanian education system in the period of 2001-2010. In order to obtain satisfactory forecasting results, constructing of models used for these aims should be grounded on some interactive data mining. Data mining of data stored in the system of the Lithuanian teacher's database and of data from other sources representing the state of education system and the demographic changes in Lithuania was used. The models cover the estimation of data quality in the databases, the analysis of flow of teachers and pupils, the clustering of schools, the model of dynamics of pedagogical staff and pupils, and the quality analysis of teachers. The main results of forecasting and integrated analysis of the Lithuanian teachers' database with other data reflecting the state of the education system and demographic changes in Lithuania are presented.

  6. System Identification, Environmental Modelling, and Control System Design

    CERN Document Server

    Garnier, Hugues

    2012-01-01

    System Identification, Environmetric Modelling, and Control Systems Design is dedicated to Professor Peter Young on the occasion of his seventieth birthday. Professor Young has been a pioneer in systems and control, and over the past 45 years he has influenced many developments in this field. This volume is comprised of a collection of contributions by leading experts in system identification, time-series analysis, environmetric modelling and control system design – modern research in topics that reflect important areas of interest in Professor Young’s research career. Recent theoretical developments in and relevant applications of these areas are explored treating the various subjects broadly and in depth. The authoritative and up-to-date research presented here will be of interest to academic researcher in control and disciplines related to environmental research, particularly those to with water systems. The tutorial style in which many of the contributions are composed also makes the book suitable as ...

  7. Heuristic approaches to models and modeling in systems biology

    NARCIS (Netherlands)

    MacLeod, Miles

    2016-01-01

    Prediction and control sufficient for reliable medical and other interventions are prominent aims of modeling in systems biology. The short-term attainment of these goals has played a strong role in projecting the importance and value of the field. In this paper I identify the standard models must m

  8. Model of the Human Sleep Wake System

    CERN Document Server

    Rogers, Lisa

    2012-01-01

    A model and analysis of the human sleep/wake system is presented. The model is derived using the known neuronal groups, and their various projections, involved with sleep and wake. Inherent in the derivation is the existence of a slow time scale associated with homeostatic regulation, and a faster time scale associated with the dynamics within the sleep phase. A significant feature of the model is that it does not contain a periodic forcing term, common in other models, reflecting the fact that sleep/wake is not dependent upon a diurnal stimulus. Once derived, the model is analyzed using a linearized stability analysis. We then use experimental data from normal sleep-wake systems and orexin knockout systems to verify the physiological validity of the equations.

  9. Modelling of Signal - Level Crossing System

    Directory of Open Access Journals (Sweden)

    Daniel Novak

    2006-01-01

    Full Text Available The author presents an object-oriented model of a railway level-crossing system created for the purpose of functional requirements specification. Unified Modelling Language (UML, version 1.4, which enables specification, visualisation, construction and documentation of software system artefacts, was used. The main attention was paid to analysis and design phases. The former phase resulted in creation of use case diagrams and sequential diagrams, the latter in creation of class/object diagrams and statechart diagrams.

  10. A Prison/Parole System Simulation Model,

    Science.gov (United States)

    parole system on future prison and parole populations. A simulation model is presented, viewing a prison / parole system as a feedback process for...ciminal offenders . Transitions among the states in which an offender might be located, imprisoned, paroled , and discharged, are assumed to be in...accordance with a discrete time semi-Markov process. Projected prison and parole populations for sample data and applications of the model are discussed. (Author)

  11. Constructing a systems psychodynamic wellness model

    OpenAIRE

    Sanchen Henning; Frans Cilliers

    2012-01-01

    Orientation: The researchers constructed a Systems Psychodynamic Wellness Model (SPWM) by merging theory and concepts from systems psychodynamics and positive psychology. They then refined the model for application in organisations during a Listening Post (LP) that comprised experienced subject experts.Research purpose: The purpose of the research was to construct and refine the SPWM in order to understand psychological wellness at the individual, group and organisational levels.Motivation fo...

  12. New Directions in Modeling the Lighting Systems

    Directory of Open Access Journals (Sweden)

    P. Fiala

    2004-12-01

    Full Text Available This paper presents information about new directions in the modelingof lighting systems, and an overview of methods for the modeling oflighting systems. The new R-FEM method is described, which is acombination of the Radiosity method and the Finite Elements Method. Thepaper contains modeling results and their verification by experimentalmeasurements and by the Matlab simulation for this R-FEM method.

  13. Quantitative Models and Analysis for Reactive Systems

    DEFF Research Database (Denmark)

    Thrane, Claus

    phones and websites. Acknowledging that now more than ever, systems come in contact with the physical world, we need to revise the way we construct models and verification algorithms, to take into account the behavior of systems in the presence of approximate, or quantitative information, provided......, allowing verification procedures to quantify judgements, on how suitable a model is for a given specification — hence mitigating the usual harsh distinction between satisfactory and non-satisfactory system designs. This information, among other things, allows us to evaluate the robustness of our framework......, by studying how small changes to our models affect the verification results. A key source of motivation for this work can be found in The Embedded Systems Design Challenge [HS06] posed by Thomas A. Henzinger and Joseph Sifakis. It contains a call for advances in the state-of-the-art of systems verification...

  14. Hybrid Energy System Modeling in Modelica

    Energy Technology Data Exchange (ETDEWEB)

    William R. Binder; Christiaan J. J. Paredis; Humberto E. Garcia

    2014-03-01

    In this paper, a Hybrid Energy System (HES) configuration is modeled in Modelica. Hybrid Energy Systems (HES) have as their defining characteristic the use of one or more energy inputs, combined with the potential for multiple energy outputs. Compared to traditional energy systems, HES provide additional operational flexibility so that high variability in both energy production and consumption levels can be absorbed more effectively. This is particularly important when including renewable energy sources, whose output levels are inherently variable, determined by nature. The specific HES configuration modeled in this paper include two energy inputs: a nuclear plant, and a series of wind turbines. In addition, the system produces two energy outputs: electricity and synthetic fuel. The models are verified through simulations of the individual components, and the system as a whole. The simulations are performed for a range of component sizes, operating conditions, and control schemes.

  15. Model Reduction of Fuzzy Logic Systems

    Directory of Open Access Journals (Sweden)

    Zhandong Yu

    2014-01-01

    Full Text Available This paper deals with the problem of ℒ2-ℒ∞ model reduction for continuous-time nonlinear uncertain systems. The approach of the construction of a reduced-order model is presented for high-order nonlinear uncertain systems described by the T-S fuzzy systems, which not only approximates the original high-order system well with an ℒ2-ℒ∞ error performance level γ but also translates it into a linear lower-dimensional system. Then, the model approximation is converted into a convex optimization problem by using a linearization procedure. Finally, a numerical example is presented to show the effectiveness of the proposed method.

  16. Economic model of pipeline transportation systems

    Energy Technology Data Exchange (ETDEWEB)

    Banks, W. F.

    1977-07-29

    The objective of the work reported here was to develop a model which could be used to assess the economic effects of energy-conservative technological innovations upon the pipeline industry. The model is a dynamic simulator which accepts inputs of two classes: the physical description (design parameters, fluid properties, and financial structures) of the system to be studied, and the postulated market (throughput and price) projection. The model consists of time-independent submodels: the fluidics model which simulates the physical behavior of the system, and the financial model which operates upon the output of the fluidics model to calculate the economics outputs. Any of a number of existing fluidics models can be used in addition to that developed as a part of this study. The financial model, known as the Systems, Science and Software (S/sup 3/) Financial Projection Model, contains user options whereby pipeline-peculiar characteristics can be removed and/or modified, so that the model can be applied to virtually any kind of business enterprise. The several dozen outputs are of two classes: the energetics and the economics. The energetics outputs of primary interest are the energy intensity, also called unit energy consumption, and the total energy consumed. The primary economics outputs are the long-run average cost, profit, cash flow, and return on investment.

  17. A multilingual programming model for coupled systems.

    Energy Technology Data Exchange (ETDEWEB)

    Ong, E. T.; Larson, J. W.; Norris, B.; Tobis, M.; Steder, M.; Jacob, R. L.; Mathematics and Computer Science; Univ. of Wisconsin; Univ. of Chicago; The Australian National Univ.

    2008-01-01

    Multiphysics and multiscale simulation systems share a common software requirement-infrastructure to implement data exchanges between their constituent parts-often called the coupling problem. On distributed-memory parallel platforms, the coupling problem is complicated by the need to describe, transfer, and transform distributed data, known as the parallel coupling problem. Parallel coupling is emerging as a new grand challenge in computational science as scientists attempt to build multiscale and multiphysics systems on parallel platforms. An additional coupling problem in these systems is language interoperability between their constituent codes. We have created a multilingual parallel coupling programming model based on a successful open-source parallel coupling library, the Model Coupling Toolkit (MCT). This programming model's capabilities reach beyond MCT's native Fortran implementation to include bindings for the C++ and Python programming languages. We describe the method used to generate the interlanguage bindings. This approach enables an object-based programming model for implementing parallel couplings in non-Fortran coupled systems and in systems with language heterogeneity. We describe the C++ and Python versions of the MCT programming model and provide short examples. We report preliminary performance results for the MCT interpolation benchmark. We describe a major Python application that uses the MCT Python bindings, a Python implementation of the control and coupling infrastructure for the community climate system model. We conclude with a discussion of the significance of this work to productivity computing in multidisciplinary computational science.

  18. The Guided System Development Framework: Modeling and Verifying Communication Systems

    DEFF Research Database (Denmark)

    Carvalho Quaresma, Jose Nuno; Probst, Christian W.; Nielson, Flemming

    2014-01-01

    In a world that increasingly relies on the Internet to function, application developers rely on the implementations of protocols to guarantee the security of data transferred. Whether a chosen protocol gives the required guarantees, and whether the implementation does the same, is usually unclear....... The Guided System Development framework contributes to more secure communication systems by aiding the development of such systems. The framework features a simple modelling language, step-wise refinement from models to implementation, interfaces to security verification tools, and code generation from...

  19. Human performance modeling for system of systems analytics :soldier fatigue.

    Energy Technology Data Exchange (ETDEWEB)

    Lawton, Craig R.; Campbell, James E.; Miller, Dwight Peter

    2005-10-01

    The military has identified Human Performance Modeling (HPM) as a significant requirement and challenge of future systems modeling and analysis initiatives as can be seen in the Department of Defense's (DoD) Defense Modeling and Simulation Office's (DMSO) Master Plan (DoD 5000.59-P 1995). To this goal, the military is currently spending millions of dollars on programs devoted to HPM in various military contexts. Examples include the Human Performance Modeling Integration (HPMI) program within the Air Force Research Laboratory, which focuses on integrating HPMs with constructive models of systems (e.g. cockpit simulations) and the Navy's Human Performance Center (HPC) established in September 2003. Nearly all of these initiatives focus on the interface between humans and a single system. This is insufficient in the era of highly complex network centric SoS. This report presents research and development in the area of HPM in a system-of-systems (SoS). Specifically, this report addresses modeling soldier fatigue and the potential impacts soldier fatigue can have on SoS performance.

  20. On modeling and controlling intelligent systems

    Energy Technology Data Exchange (ETDEWEB)

    Dress, W.B.

    1993-11-01

    The aim of this paper is to show how certain diverse and advanced techniques of information processing and system theory might be integrated into a model of an intelligent, complex entity capable of materially enhancing an advanced information management system. To this end, we first examine the notion of intelligence and ask whether a semblance thereof can arise in a system consisting of ensembles of finite-state automata. Our goal is to find a functional model of intelligence in an information-management setting that can be used as a tool. The purpose of this tool is to allow us to create systems of increasing complexity and utility, eventually reaching the goal of an intelligent information management system that provides and anticipates needed data and information. We base our attempt on the ideas of general system theory where the four topics of system identification, modeling, optimization, and control provide the theoretical framework for constructing a complex system that will be capable of interacting with complex systems in the real world. These four key topics are discussed within the purview of cellular automata, neural networks, and evolutionary programming. This is a report of ongoing work, and not yet a success story of a synthetic intelligent system.

  1. On modeling and controlling intelligent systems

    Energy Technology Data Exchange (ETDEWEB)

    Dress, W.B.

    1993-11-01

    The aim of this paper is to show how certain diverse and advanced techniques of information processing and system theory might be integrated into a model of an intelligent, complex entity capable of materially enhancing an advanced information management system. To this end, we first examine the notion of intelligence and ask whether a semblance thereof can arise in a system consisting of ensembles of finite-state automata. Our goal is to find a functional model of intelligence in an information-management setting that can be used as a tool. The purpose of this tool is to allow us to create systems of increasing complexity and utility, eventually reaching the goal of an intelligent information management system that provides and anticipates needed data and information. We base our attempt on the ideas of general system theory where the four topics of system identification, modeling, optimization, and control provide the theoretical framework for constructing a complex system that will be capable of interacting with complex systems in the real world. These four key topics are discussed within the purview of cellular automata, neural networks, and evolutionary programming. This is a report of ongoing work, and not yet a success story of a synthetic intelligent system.

  2. Behavioral Reference Model for Pervasive Healthcare Systems.

    Science.gov (United States)

    Tahmasbi, Arezoo; Adabi, Sahar; Rezaee, Ali

    2016-12-01

    The emergence of mobile healthcare systems is an important outcome of application of pervasive computing concepts for medical care purposes. These systems provide the facilities and infrastructure required for automatic and ubiquitous sharing of medical information. Healthcare systems have a dynamic structure and configuration, therefore having an architecture is essential for future development of these systems. The need for increased response rate, problem limited storage, accelerated processing and etc. the tendency toward creating a new generation of healthcare system architecture highlight the need for further focus on cloud-based solutions for transfer data and data processing challenges. Integrity and reliability of healthcare systems are of critical importance, as even the slightest error may put the patients' lives in danger; therefore acquiring a behavioral model for these systems and developing the tools required to model their behaviors are of significant importance. The high-level designs may contain some flaws, therefor the system must be fully examined for different scenarios and conditions. This paper presents a software architecture for development of healthcare systems based on pervasive computing concepts, and then models the behavior of described system. A set of solutions are then proposed to improve the design's qualitative characteristics including, availability, interoperability and performance.

  3. XML Model of Planning System in Foundry

    Directory of Open Access Journals (Sweden)

    A. Stawowy

    2007-07-01

    Full Text Available Contemporary enterprises (including those manufacturing iron castings have at their disposal advanced computer resources for the management of production processes. The disadvantage of these solutions is an incoherent language for writing production planning and scheduling problems. The lack of the standard for data exchange and model description makes the work on designing, development and implementation difficult. Various dialects of XML language, among others for production planning purposes, which may change this situation have been developed for the last several years. The paper describes a PSLX language, which can be viewed first of all as an ontology and communication protocol inside and outside of the Advanced Planning and Scheduling (APS system, as well as an XML standard for production planning and scheduling. This language has been then used to develop a model of planning system in a foundry. The model consists of customer’s order model, resources model and scheduling model.

  4. Externalizing Behaviour for Analysing System Models

    DEFF Research Database (Denmark)

    Ivanova, Marieta Georgieva; Probst, Christian W.; Hansen, René Rydhof

    2013-01-01

    attackers. Therefore, many attacks are considerably easier to be performed for insiders than for outsiders. However, current models do not support explicit specification of different behaviours. Instead, behaviour is deeply embedded in the analyses supported by the models, meaning that it is a complex......, if not impossible task to change behaviours. Especially when considering social engineering or the human factor in general, the ability to use different kinds of behaviours is essential. In this work we present an approach to make the behaviour a separate component in system models, and explore how to integrate......System models have recently been introduced to model organisations and evaluate their vulnerability to threats and especially insider threats. Especially for the latter these models are very suitable, since insiders can be assumed to have more knowledge about the attacked organisation than outside...

  5. Reusing knowledge in embedded system modelling

    NARCIS (Netherlands)

    Marincic, J.; Mader, Angelika H.; Wieringa, Roelf J.; Lucas, Yan

    2013-01-01

    Model-based design is a promising technique to improve the quality of software and the efficiency of the software development process. We are investigating how to efficiently model embedded software and its environment to verify the requirements for the system controlled by the software. The softwar

  6. Complex Systems and Human Performance Modeling

    Science.gov (United States)

    2013-12-01

    constitute a cognitive architecture or decomposing the work flows and resource constraints that characterize human-system interactions, the modeler...also explored the generation of so-called “ fractal ” series from simple task network models where task times are the calculated by way of a moving

  7. Immune System Model Calibration by Genetic Algorithm

    NARCIS (Netherlands)

    Presbitero, A.; Krzhizhanovskaya, V.; Mancini, E.; Brands, R.; Sloot, P.

    2016-01-01

    We aim to develop a mathematical model of the human immune system for advanced individualized healthcare where medication plan is fine-tuned to fit a patient's conditions through monitored biochemical processes. One of the challenges is calibrating model parameters to satisfy existing experimental

  8. Test-driven modeling of embedded systems

    DEFF Research Database (Denmark)

    Munck, Allan; Madsen, Jan

    2015-01-01

    To benefit maximally from model-based systems engineering (MBSE) trustworthy high quality models are required. From the software disciplines it is known that test-driven development (TDD) can significantly increase the quality of the products. Using a test-driven approach with MBSE may have a sim...

  9. A system dynamics model for communications networks

    Science.gov (United States)

    Awcock, A. J.; King, T. E. G.

    1985-09-01

    An abstract model of a communications network in system dynamics terminology is developed as implementation of this model by a FORTRAN program package developed at RSRE is discussed. The result of this work is a high-level simulation package in which the performance of adaptive routing algorithms and other network controls may be assessed for a network of arbitrary topology.

  10. System level modelling with open source tools

    DEFF Research Database (Denmark)

    Jakobsen, Mikkel Koefoed; Madsen, Jan; Niaki, Seyed Hosein Attarzadeh;

    , called ForSyDe. ForSyDe is available under the open Source approach, which allows small and medium enterprises (SME) to get easy access to advanced modeling capabilities and tools. We give an introduction to the design methodology through the system level modeling of a simple industrial use case, and we...

  11. Probabilistic modeling of solar power systems

    Science.gov (United States)

    Safie, Fayssal M.

    1989-01-01

    The author presents a probabilistic approach based on Markov chain theory to model stand-alone photovoltaic power systems and predict their long-term service performance. The major advantage of this approach is that it allows designers and developers of these systems to analyze the system performance as well as the battery subsystem performance in the long run and determine the system design requirements that meet a specified service performance level. The methodology presented is illustrated by using data for a radio repeater system for the Boston, Massachusetts, location.

  12. Cost and Performance Model for Photovoltaic Systems

    Science.gov (United States)

    Borden, C. S.; Smith, J. H.; Davisson, M. C.; Reiter, L. J.

    1986-01-01

    Lifetime cost and performance (LCP) model assists in assessment of design options for photovoltaic systems. LCP is simulation of performance, cost, and revenue streams associated with photovoltaic power systems connected to electric-utility grid. LCP provides user with substantial flexibility in specifying technical and economic environment of application.

  13. Economic Models and Algorithms for Distributed Systems

    CERN Document Server

    Neumann, Dirk; Altmann, Jorn; Rana, Omer F

    2009-01-01

    Distributed computing models for sharing resources such as Grids, Peer-to-Peer systems, or voluntary computing are becoming increasingly popular. This book intends to discover fresh avenues of research and amendments to existing technologies, aiming at the successful deployment of commercial distributed systems

  14. Eclectic Model in the Malaysian Education System

    Science.gov (United States)

    Othman, Nooraini; Mohamad, Khairul Azmi; Ilmuwan, Yayasan

    2011-01-01

    The present work aims at analysing the adoption of eclectic model in the Malaysian education system. The analysis is specifically looked from the angle of Islam and the Muslims. Malaysia has a long history of education system developments, from pre to post independence of the country. From what was initially traditional, modernity later came to…

  15. CTBT Integrated Verification System Evaluation Model

    Energy Technology Data Exchange (ETDEWEB)

    Edenburn, M.W.; Bunting, M.L.; Payne, A.C. Jr.

    1997-10-01

    Sandia National Laboratories has developed a computer based model called IVSEM (Integrated Verification System Evaluation Model) to estimate the performance of a nuclear detonation monitoring system. The IVSEM project was initiated in June 1994, by Sandia`s Monitoring Systems and Technology Center and has been funded by the US Department of Energy`s Office of Nonproliferation and National Security (DOE/NN). IVSEM is a simple, top-level, modeling tool which estimates the performance of a Comprehensive Nuclear Test Ban Treaty (CTBT) monitoring system and can help explore the impact of various sensor system concepts and technology advancements on CTBT monitoring. One of IVSEM`s unique features is that it integrates results from the various CTBT sensor technologies (seismic, infrasound, radionuclide, and hydroacoustic) and allows the user to investigate synergy among the technologies. Specifically, IVSEM estimates the detection effectiveness (probability of detection) and location accuracy of the integrated system and of each technology subsystem individually. The model attempts to accurately estimate the monitoring system`s performance at medium interfaces (air-land, air-water) and for some evasive testing methods such as seismic decoupling. This report describes version 1.2 of IVSEM.

  16. Fem Modelling of Lumbar Vertebra System

    Directory of Open Access Journals (Sweden)

    Rimantas Kačianauskas

    2014-02-01

    Full Text Available The article presents modeling of human lumbar vertebra and it‘sdeformation analysis using finite elements method. The problemof tissue degradation is raised. Using the computer aided modelingwith SolidWorks software the models of lumbar vertebra(L1 and vertebra system L1-L4 were created. The article containssocial and medical problem analysis, description of modelingmethods and the results of deformation test for one vertebramodel and for model of 4 vertebras (L1-L4.

  17. Power electronics system modeling and simulation

    Energy Technology Data Exchange (ETDEWEB)

    Lai, Jih-Sheng

    1994-12-31

    This paper introduces control system design based softwares, SIMNON and MATLAB/SIMULINK, for power electronics system simulation. A complete power electronics system typically consists of a rectifier bridge along with its smoothing capacitor, an inverter, and a motor. The system components, featuring discrete or continuous, linear or nonlinear, are modeled in mathematical equations. Inverter control methods,such as pulse-width-modulation and hysteresis current control, are expressed in either computer algorithms or digital circuits. After describing component models and control methods, computer programs are then developed for complete systems simulation. Simulation results are mainly used for studying system performances, such as input and output current harmonics, torque ripples, and speed responses. Key computer programs and simulation results are demonstrated for educational purposes.

  18. Modelling and control of dynamic systems using gaussian process models

    CERN Document Server

    Kocijan, Juš

    2016-01-01

    This monograph opens up new horizons for engineers and researchers in academia and in industry dealing with or interested in new developments in the field of system identification and control. It emphasizes guidelines for working solutions and practical advice for their implementation rather than the theoretical background of Gaussian process (GP) models. The book demonstrates the potential of this recent development in probabilistic machine-learning methods and gives the reader an intuitive understanding of the topic. The current state of the art is treated along with possible future directions for research. Systems control design relies on mathematical models and these may be developed from measurement data. This process of system identification, when based on GP models, can play an integral part of control design in data-based control and its description as such is an essential aspect of the text. The background of GP regression is introduced first with system identification and incorporation of prior know...

  19. Chain modeling for life cycle systems engineering

    Energy Technology Data Exchange (ETDEWEB)

    Rivera, J.J. [Sandia National Lab., Albuquerque, NM (United States); Shapiro, V. [Univ. of Wisconsin, Madison, WI (United States). Spatial Automation Lab.

    1997-12-01

    Throughout Sandia`s history, products have been represented by drawings. Solid modeling systems have recently replaced drawings as the preferred means for representing product geometry. These systems are used for product visualization, engineering analysis and manufacturing planning. Unfortunately, solid modeling technology is inadequate for life cycle systems engineering, which requires maintenance of technical history, efficient management of geometric and non-geometric data, and explicit representation of engineering and manufacturing characteristics. Such information is not part of the mathematical foundation of solid modeling. The current state-of-the-art in life cycle engineering is comprised of painstakingly created special purpose tools, which often are incompatible. New research on {open_quotes}chain modeling{close_quotes} provides a method of chaining the functionality of a part to the geometric representation. Chain modeling extends classical solid modeling to include physical, manufacturing, and procedural information required for life cycle engineering. In addition, chain modeling promises to provide the missing theoretical basis for Sandia`s parent/child product realization paradigm. In chain modeling, artifacts and systems are characterized in terms of their combinatorial properties: cell complexes, chains, and their operators. This approach is firmly rooted in algebraic topology and is a natural extension of current technology. The potential benefits of this approach include explicit hierarchical and combinatorial representation of physics, geometry, functionality, test, and legacy data in a common computational framework that supports a rational decision process and partial design automation. Chain modeling will have a significant impact on design preservation, system identification, parameterization, system reliability, and design simplification.

  20. World energy projection system: Model documentation

    Energy Technology Data Exchange (ETDEWEB)

    1992-06-01

    The World Energy Project System (WEPS) is an accounting framework that incorporates projects from independently documented models and assumptions about the future energy intensity of economic activity (ratios of total energy consumption divided by gross domestic product) and about the rate of incremental energy requirements met by hydropower, geothermal, coal, and natural gas to produce projections of world energy consumption published annually by the Energy Information Administration (EIA) in the International Energy Outlook (IEO) (Figure 1). Two independently documented models presented in Figure 1, the Oil Market Simulation (OMS) model and the World Integrated Nuclear Evaluation System (WINES) provide projections of oil and nuclear power consumption published in the IEO. Output from a third independently documented model, and the International Coal Trade Model (ICTM), is not published in the IEO but is used in WEPS as a supply check on projections of world coal consumption produced by WEPS and published in the IEO. A WEPS model of natural gas production documented in this report provides the same type of implicit supply check on the WEPS projections of world natural gas consumption published in the IEO. Two additional models are included in Figure 1, the OPEC Capacity model and the Non-OPEC Oil Production model. These WEPS models provide inputs to the OMS model and are documented in this report.

  1. Systemic change increases model projection uncertainty

    Science.gov (United States)

    Verstegen, Judith; Karssenberg, Derek; van der Hilst, Floor; Faaij, André

    2014-05-01

    Most spatio-temporal models are based on the assumption that the relationship between system state change and its explanatory processes is stationary. This means that model structure and parameterization are usually kept constant over time, ignoring potential systemic changes in this relationship resulting from e.g., climatic or societal changes, thereby overlooking a source of uncertainty. We define systemic change as a change in the system indicated by a system state change that cannot be simulated using a constant model structure. We have developed a method to detect systemic change, using a Bayesian data assimilation technique, the particle filter. The particle filter was used to update the prior knowledge about the model structure. In contrast to the traditional particle filter approach (e.g., Verstegen et al., 2014), we apply the filter separately for each point in time for which observations are available, obtaining the optimal model structure for each of the time periods in between. This allows us to create a time series of the evolution of the model structure. The Runs test (Wald and Wolfowitz, 1940), a stationarity test, is used to check whether variation in this time series can be attributed to randomness or not. If not, this indicates systemic change. The uncertainty that the systemic change adds to the existing model projection uncertainty can be determined by comparing model outcomes of a model with a stationary model structure and a model with a model structure changing according to the variation found in the time series. To test the systemic change detection methodology, we apply it to a land use change cellular automaton (CA) (Verstegen et al., 2012) and use observations of real land use from all years from 2004 to 2012 and associated uncertainty as observational data in the particle filter. A systemic change was detected for the period 2006 to 2008. In this period the influence on the location of sugar cane expansion of the driver sugar cane in

  2. Information systems validation using formal models

    Directory of Open Access Journals (Sweden)

    Azadeh Sarram

    2014-03-01

    Full Text Available During the past few years, there has been growing interest to use unified modeling language (UML to consider the functional requirements. However, lacking a tool to detect the accuracy and the logic of diagrams in this language makes a formal model indispensable. In this study, conversion of primary UML model of a system to a colored Petri net has been accomplished in order to examine the precision of the model. For this purpose, first the definition of priority and implementation tags for UML activity diagram are provided; then it is turned into colored Petri net. Second, the proposed model provides translated tags in terms of net transitions and some monitoring are used to control the system characteristics. Finally, an executable model of UML activity diagram is provided so that the designer could simulate the model by using the simulation results to detect and to refine the problems of the model. In addition, by checking the results, we find out the proposed method enhances authenticity and accuracy of early models and the ratio of system validation increases compared with previous methods.

  3. Reactivity of the metal-->BX3 dative sigma-bond: 1,2-addition reactions of the Fe-->BX3 moiety of the ferraboratrane complex [kappa4-B(mimBu t)3]Fe(CO)2.

    Science.gov (United States)

    Figueroa, Joshua S; Melnick, Jonathan G; Parkin, Gerard

    2006-09-04

    The ferraboratrane [kappa4-B(mim(Bu)t)3]Fe(CO)2 (mim(Bu)t = 2-mercapto-1-tert-butylimidazolyl), the first example of a complex which possesses a retrodative (i.e., metal-to-ligand) Fe-->B bond, is obtained via reaction of the tris(2-mercapto-1-tert-butylimidazolyl)hydroborato complex [Tm(Bu)t]FeCl with LiCH2SiMe3 followed by treatment with CO. Significantly, [kappa4-B(mim(Bu)t)3]Fe(CO)2 exhibits novel reactivity towards a variety of reagents that results in eradication of the Fe-->B bond via a formal 1,2-addition process and the formation of B-functionalized tris(mercaptoimidazolyl)borate derivatives, [XTm(Bu)t]FeY.

  4. Security Communication Model of Wireless Trade System

    Institute of Scientific and Technical Information of China (English)

    ZHANG Wen-kai; ZHANG Si-yu

    2005-01-01

    This paper proposes a C/S system model for K Java and PDA named Net-Wireless. It is a discussion and proposal on information security and solutions for K-Java handsets and PDAs in wireless network. It also explains the scheme which between client security module and server security module. Also, We have developed a Security Server and a K-Java encryption module for e-commerce system and other trade systems.

  5. Expert System Model for Educational Personnel Selection

    Directory of Open Access Journals (Sweden)

    Héctor A. Tabares-Ospina

    2013-06-01

    Full Text Available The staff selection is a difficult task due to the subjectivity that the evaluation means. This process can be complemented using a system to support decision. This paper presents the implementation of an expert system to systematize the selection process of professors. The management of software development is divided into 4 parts: requirements, design, implementation and commissioning. The proposed system models a specific knowledge through relationships between variables evidence and objective.

  6. PENAKERJA: IMPLEMENTASI PERMENDIKBUD NOMOR 111 TAHUN 2014 TENTANG BIMBINGAN DAN KONSELING PADA PENDIDIKAN DASAR DAN MENENGAH DI SD MUHHAMMADIYAH PK SURAKARTA DAN MIM PK KARTASURA

    Directory of Open Access Journals (Sweden)

    Saring Marsudi

    2015-09-01

    Full Text Available The general objective of this community service activity is facilitating the theoretical and practical BK services in Muhammadiyah Elementary School of Special Program in Surakarta and MIM Kartasura in implementing Permendikbud No. 111 of 2014 in an effort to improve the professionalism of teachers. In particular, the purpose of the community service is to facilitate the understanding the partner schools in Counselling services in the areas of personal, social, learning, and career. The service activities include socialization Permendikbud No. 111 of 2014 concerning guidance and counseling services in primary school, a discussion on the basic concept of guidance and counseling, and workshops on the implementation of guidance and counseling in Muhammadiyah Elementary School of Special Program in Surakarta and MIM Kartasura. Community service activities have received positive responses namely the formation of a formal institution Institute of Guidance and Counseling in each school. These institutions equipped with the personnel in charge, coordinator and teacher who oversees areas: personal, social, learning, and career.

  7. Model Based Control of Refrigeration Systems

    DEFF Research Database (Denmark)

    Larsen, Lars Finn Sloth

    of the supermarket refrigeration systems therefore greatly relies on a human operator to detect and accommodate failures, and to optimize system performance under varying operational condition. Today these functions are maintained by monitoring centres located all over the world. Initiated by the growing need...... for automation of these procedures, that is to incorporate some "intelligence" in the control system, this project was started up. The main emphasis of this work has been on model based methods for system optimizing control in supermarket refrigeration systems. The idea of implementing a system optimizing.......e. by degrading the performance. The method has been successfully applied on a test frigeration system for minimization of the power consumption; the hereby gained experimental results will be presented. The present control structure in a supermarket refrigeration system is distributed, which means...

  8. Business Models for Power System Flexibility

    DEFF Research Database (Denmark)

    Boscan, Luis; Poudineh, Rahmatallah

    2016-01-01

    -enabling business models, adding new activities to the existing supply chain. Ranging from technological to market-based innovation, this chapter reviews the latest developments in these emerging models. The main conclusion is that when flexibility becomes scarce in the system, new players with their innovative......As intermittent, renewable resources gain more share in the generation mix, the need for power system flexibility increases more than ever. Parallel to this, technological change and the emergence of new players bringing about innovative solutions are boosting the development of flexibility...... business models will play an important role in ensuring sufficiency and efficiency of flexibility services....

  9. Application of RBAC Model in System Kernel

    Directory of Open Access Journals (Sweden)

    Guan Keqing

    2012-11-01

    Full Text Available In the process of development of some technologies about Ubiquitous computing, the application of embedded intelligent devices is booming. Meanwhile, information security will face more serious threats than before. To improve the security of information terminal’s operation system, this paper analyzed the threats to system’s information security which comes from the abnormal operation by processes, and applied RBAC model into the safety management mechanism of operation system’s kernel. We built an access control model of system’s process, and proposed an implement framework. And the methods of implementation of the model for operation systems were illustrated.

  10. OFFl Models: Novel Schema for Dynamical Modeling of Biological Systems.

    Science.gov (United States)

    Ogbunugafor, C Brandon; Robinson, Sean P

    2016-01-01

    Flow diagrams are a common tool used to help build and interpret models of dynamical systems, often in biological contexts such as consumer-resource models and similar compartmental models. Typically, their usage is intuitive and informal. Here, we present a formalized version of flow diagrams as a kind of weighted directed graph which follow a strict grammar, which translate into a system of ordinary differential equations (ODEs) by a single unambiguous rule, and which have an equivalent representation as a relational database. (We abbreviate this schema of "ODEs and formalized flow diagrams" as OFFL.) Drawing a diagram within this strict grammar encourages a mental discipline on the part of the modeler in which all dynamical processes of a system are thought of as interactions between dynamical species that draw parcels from one or more source species and deposit them into target species according to a set of transformation rules. From these rules, the net rate of change for each species can be derived. The modeling schema can therefore be understood as both an epistemic and practical heuristic for modeling, serving both as an organizational framework for the model building process and as a mechanism for deriving ODEs. All steps of the schema beyond the initial scientific (intuitive, creative) abstraction of natural observations into model variables are algorithmic and easily carried out by a computer, thus enabling the future development of a dedicated software implementation. Such tools would empower the modeler to consider significantly more complex models than practical limitations might have otherwise proscribed, since the modeling framework itself manages that complexity on the modeler's behalf. In this report, we describe the chief motivations for OFFL, carefully outline its implementation, and utilize a range of classic examples from ecology and epidemiology to showcase its features.

  11. OFFl Models: Novel Schema for Dynamical Modeling of Biological Systems.

    Directory of Open Access Journals (Sweden)

    C Brandon Ogbunugafor

    Full Text Available Flow diagrams are a common tool used to help build and interpret models of dynamical systems, often in biological contexts such as consumer-resource models and similar compartmental models. Typically, their usage is intuitive and informal. Here, we present a formalized version of flow diagrams as a kind of weighted directed graph which follow a strict grammar, which translate into a system of ordinary differential equations (ODEs by a single unambiguous rule, and which have an equivalent representation as a relational database. (We abbreviate this schema of "ODEs and formalized flow diagrams" as OFFL. Drawing a diagram within this strict grammar encourages a mental discipline on the part of the modeler in which all dynamical processes of a system are thought of as interactions between dynamical species that draw parcels from one or more source species and deposit them into target species according to a set of transformation rules. From these rules, the net rate of change for each species can be derived. The modeling schema can therefore be understood as both an epistemic and practical heuristic for modeling, serving both as an organizational framework for the model building process and as a mechanism for deriving ODEs. All steps of the schema beyond the initial scientific (intuitive, creative abstraction of natural observations into model variables are algorithmic and easily carried out by a computer, thus enabling the future development of a dedicated software implementation. Such tools would empower the modeler to consider significantly more complex models than practical limitations might have otherwise proscribed, since the modeling framework itself manages that complexity on the modeler's behalf. In this report, we describe the chief motivations for OFFL, carefully outline its implementation, and utilize a range of classic examples from ecology and epidemiology to showcase its features.

  12. Modeling the heart and the circulatory system

    CERN Document Server

    2015-01-01

    The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the preprocessing of clinical data to the development of mathematical equations, their numerical solution, and both in-vivo and in-vitro validation. They discuss the flow in the systemic arterial tree and the complex electro-fluid-mechanical coupling in the human heart. Many examples of patient-specific simulations are presented. This book is addressed to all scientists interested in the mathematical modeling and numerical simulation of the human cardiocirculatory system.

  13. Modeling and simulation of discrete event systems

    CERN Document Server

    Choi, Byoung Kyu

    2013-01-01

    Computer modeling and simulation (M&S) allows engineers to study and analyze complex systems. Discrete-event system (DES)-M&S is used in modern management, industrial engineering, computer science, and the military. As computer speeds and memory capacity increase, so DES-M&S tools become more powerful and more widely used in solving real-life problems. Based on over 20 years of evolution within a classroom environment, as well as on decades-long experience in developing simulation-based solutions for high-tech industries, Modeling and Simulation of Discrete-Event Systems is the only book on

  14. Modelling ecological systems in a changing world.

    Science.gov (United States)

    Evans, Matthew R

    2012-01-19

    The world is changing at an unprecedented rate. In such a situation, we need to understand the nature of the change and to make predictions about the way in which it might affect systems of interest; often we may also wish to understand what might be done to mitigate the predicted effects. In ecology, we usually make such predictions (or forecasts) by making use of mathematical models that describe the system and projecting them into the future, under changed conditions. Approaches emphasizing the desirability of simple models with analytical tractability and those that use assumed causal relationships derived statistically from data currently dominate ecological modelling. Although such models are excellent at describing the way in which a system has behaved, they are poor at predicting its future state, especially in novel conditions. In order to address questions about the impact of environmental change, and to understand what, if any, action might be taken to ameliorate it, ecologists need to develop the ability to project models into novel, future conditions. This will require the development of models based on understanding the processes that result in a system behaving the way it does, rather than relying on a description of the system, as a whole, remaining valid indefinitely.

  15. Intelligent Mechatronic Systems Modeling, Control and Diagnosis

    CERN Document Server

    Merzouki, Rochdi; Pathak, Pushparaj Mani; Ould Bouamama, Belkacem

    2013-01-01

    Acting as a support resource for practitioners and professionals looking to advance their understanding of complex mechatronic systems, Intelligent Mechatronic Systems explains their design and recent developments from first principles to practical applications. Detailed descriptions of the mathematical models of complex mechatronic systems, developed from fundamental physical relationships, are built on to develop innovative solutions with particular emphasis on physical model-based control strategies. Following a concurrent engineering approach, supported by industrial case studies, and drawing on the practical experience of the authors, Intelligent Mechatronic Systems covers range of topic and includes:  • An explanation of a common graphical tool for integrated design and its uses from modeling and simulation to the control synthesis • Introductions to key concepts such as different means of achieving fault tolerance, robust overwhelming control and force and impedance control • Dedicated chapters ...

  16. Modelling and Analysing Socio-Technical Systems

    DEFF Research Database (Denmark)

    Aslanyan, Zaruhi; Ivanova, Marieta Georgieva; Nielson, Flemming

    2015-01-01

    with social engineering. Due to this combination of attack steps on technical and social levels, risk assessment in socio-technical systems is complex. Therefore, established risk assessment methods often abstract away the internal structure of an organisation and ignore human factors when modelling...... and assessing attacks. In our work we model all relevant levels of socio-technical systems, and propose evaluation techniques for analysing the security properties of the model. Our approach simplifies the identification of possible attacks and provides qualified assessment and ranking of attacks based...... on the expected impact. We demonstrate our approach on a home-payment system. The system is specifically designed to help elderly or disabled people, who may have difficulties leaving their home, to pay for some services, e.g., care-taking or rent. The payment is performed using the remote control of a television...

  17. Incremental System Modelling in Event-B

    DEFF Research Database (Denmark)

    Hallerstede, Stefan

    2009-01-01

    the specification is the right one for the given requirements. Sometimes requirements also concern features of a system closely related to its implementation. This would make an abstract specification necessarily incomplete. We believe that it is better not to follow the rigid approach to modelling described above......A reasonable approach to formal modelling is to start with a specification that captures the requirements of a system and then use formal refinement to implement it. The problem with this approach is that for complex systems the specification itself is complex. It becomes a challenge to say whether....... Instead, we argue that the specification itself should be elaborated by refinement. Ultimately, the distinction between specification and implementation is no longer made in the strict sense above. There is only one model of the system that is connected by successive refinements. Using Event-B, we...

  18. Model Based Testing for Agent Systems

    Science.gov (United States)

    Zhang, Zhiyong; Thangarajah, John; Padgham, Lin

    Although agent technology is gaining world wide popularity, a hindrance to its uptake is the lack of proper testing mechanisms for agent based systems. While many traditional software testing methods can be generalized to agent systems, there are many aspects that are different and which require an understanding of the underlying agent paradigm. In this paper we present certain aspects of a testing framework that we have developed for agent based systems. The testing framework is a model based approach using the design models of the Prometheus agent development methodology. In this paper we focus on model based unit testing and identify the appropriate units, present mechanisms for generating suitable test cases and for determining the order in which the units are to be tested, present a brief overview of the unit testing process and an example. Although we use the design artefacts from Prometheus the approach is suitable for any plan and event based agent system.

  19. Stochastic Modelling Of The Repairable System

    Directory of Open Access Journals (Sweden)

    Andrzejczak Karol

    2015-11-01

    Full Text Available All reliability models consisting of random time factors form stochastic processes. In this paper we recall the definitions of the most common point processes which are used for modelling of repairable systems. Particularly this paper presents stochastic processes as examples of reliability systems for the support of the maintenance related decisions. We consider the simplest one-unit system with a negligible repair or replacement time, i.e., the unit is operating and is repaired or replaced at failure, where the time required for repair and replacement is negligible. When the repair or replacement is completed, the unit becomes as good as new and resumes operation. The stochastic modelling of recoverable systems constitutes an excellent method of supporting maintenance related decision-making processes and enables their more rational use.

  20. User Modeling for Personalized Recommender Systems

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    This paper models a user's interest and value related characteristics based on the extension by using neural networks and econometric techniques to the concept of user model in recommender systems. A two-dimensional taxonomy of user model was proposed in terms of the content and persistence of user characteristics. A user interest model and a customer lifetime value model were developed for the proposed taxonomy framework, to capture the time-dependent evolving nature of user's interests and his/her long-term profitability. The proposed models were empirically validated by using real customer data from a bee product company in health care industry. The experimental results show that these models provide effective assistant tools for the company to target its most valuable customers and implement one-to-one personalized services.

  1. Summary of photovoltaic system performance models

    Energy Technology Data Exchange (ETDEWEB)

    Smith, J. H.; Reiter, L. J.

    1984-01-15

    The purpose of this study is to provide a detailed overview of photovoltaics (PV) performance modeling capabilities that have been developed during recent years for analyzing PV system and component design and policy issues. A set of 10 performance models have been selected which span a representative range of capabilities from generalized first-order calculations to highly specialized electrical network simulations. A set of performance modeling topics and characteristics is defined and used to examine some of the major issues associated with photovoltaic performance modeling. Next, each of the models is described in the context of these topics and characteristics to assess its purpose, approach, and level of detail. Then each of the issues is discussed in terms of the range of model capabilities available and summarized in tabular form for quick reference. Finally, the models are grouped into categories to illustrate their purposes and perspectives.

  2. Advanced modelling of optical coherence tomography systems

    DEFF Research Database (Denmark)

    Andersen, Peter E.; Thrane, L.; Yura, H.T.;

    2004-01-01

    Analytical and numerical models for describing and understanding the light propagation in samples imaged by optical coherence tomography (OCT) systems are presented. An analytical model for calculating the OCT signal based on the extended Huygens–Fresnel principle valid both for the single...... and multiple scattering regimes is reviewed. An advanced Monte Carlo model for calculating the OCT signal is also reviewed, and the validity of this model is shown through a mathematical proof based on the extended Huygens–Fresnel principle. Moreover, for the first time the model is verified experimentally....... From the analytical model, an algorithm for enhancing OCT images is developed; the so-called true-reflection algorithm in which the OCT signal may be corrected for the attenuation caused by scattering. For the first time, the algorithm is demonstrated by using the Monte Carlo model as a numerical...

  3. Brand Equity Evolution: a System Dynamics Model

    Directory of Open Access Journals (Sweden)

    Edson Crescitelli

    2009-04-01

    Full Text Available One of the greatest challenges in brand management lies in monitoring brand equity over time. This paper aimsto present a simulation model able to represent this evolution. The model was drawn on brand equity concepts developed by Aaker and Joachimsthaler (2000, using the system dynamics methodology. The use ofcomputational dynamic models aims to create new sources of information able to sensitize academics and managers alike to the dynamic implications of their brand management. As a result, an easily implementable model was generated, capable of executing continuous scenario simulations by surveying casual relations among the variables that explain brand equity. Moreover, the existence of a number of system modeling tools will allow extensive application of the concepts used in this study in practical situations, both in professional and educational settings

  4. Model validation in soft systems practice

    Energy Technology Data Exchange (ETDEWEB)

    Checkland, P. [Univ. of Lancaster (United Kingdom)

    1995-03-01

    The concept of `a model` usually evokes the connotation `model of part of the real world`. That is an almost automatic response. It makes sense especially in relation to the way the concept has been developed and used in natural science. Classical operational research (OR), with its scientific aspirations, and systems engineering, use the concept in the same way and in addition use models as surrogates for the real world, on which experimentation is cheap. In these fields the key feature of a model is representativeness. In soft systems methodology (SSM) models are not of part of the world; they are only relevant to debate about the real world and are used in a cyclic learning process. The paper shows how the different concepts of validation in classical OR and SSM lead to a way of sharply defining the nature of `soft OR`. 21 refs.

  5. OFFl Models: Novel Schema for Dynamical Modeling of Biological Systems

    Science.gov (United States)

    2016-01-01

    Flow diagrams are a common tool used to help build and interpret models of dynamical systems, often in biological contexts such as consumer-resource models and similar compartmental models. Typically, their usage is intuitive and informal. Here, we present a formalized version of flow diagrams as a kind of weighted directed graph which follow a strict grammar, which translate into a system of ordinary differential equations (ODEs) by a single unambiguous rule, and which have an equivalent representation as a relational database. (We abbreviate this schema of “ODEs and formalized flow diagrams” as OFFL.) Drawing a diagram within this strict grammar encourages a mental discipline on the part of the modeler in which all dynamical processes of a system are thought of as interactions between dynamical species that draw parcels from one or more source species and deposit them into target species according to a set of transformation rules. From these rules, the net rate of change for each species can be derived. The modeling schema can therefore be understood as both an epistemic and practical heuristic for modeling, serving both as an organizational framework for the model building process and as a mechanism for deriving ODEs. All steps of the schema beyond the initial scientific (intuitive, creative) abstraction of natural observations into model variables are algorithmic and easily carried out by a computer, thus enabling the future development of a dedicated software implementation. Such tools would empower the modeler to consider significantly more complex models than practical limitations might have otherwise proscribed, since the modeling framework itself manages that complexity on the modeler’s behalf. In this report, we describe the chief motivations for OFFL, carefully outline its implementation, and utilize a range of classic examples from ecology and epidemiology to showcase its features. PMID:27270918

  6. Prototype models for the MOIRA computerised system

    Energy Technology Data Exchange (ETDEWEB)

    Monte, Luigi [ENEA, Centro Ricerche Casaccia, Rome (Italy). Dipt. Ambiente; Hakanson, Lars [Uppsala, Univ. (Sweden). Institute of Earth Sciences; Brittain, John [Oslo, Univ. (Norway). Zoological Museum

    1997-06-01

    The main aim of the present report is to describe selected models and the principles of the Decision Analysis theory that will be applied to develop the model-based computerised system `MOIRA`. A dose model and a model for predicting radiocaesium migration in lakes and the effects of countermeasures to reduce the contamination levels in the components of lacustrine system are described in detail. The principles for developing prototype models for predicting the migration of {sup 90}Sr in lake abiotic and biotic components are discussed. The environmental models described in the report are based on the use of `collective parameters` which due to mutual compensation effects of different phenomena occurring in complex systems, show low variability when the environmental conditions change. Use of such `collective parameters` not only increases the predictive power of the models, but also increases the practical applicability of the model. Among the main results described in the report, the development of an objective hierarchy table for evaluating the effectiveness of a countermeasure when the economic, social and ecological impacts are accounted for, deserves special attention.

  7. Integrated Modeling for Flood Hazard Mapping Using Watershed Modeling System

    Directory of Open Access Journals (Sweden)

    Seyedeh S. Sadrolashrafi

    2008-01-01

    Full Text Available In this stduy, a new framework which integrates the Geographic Information System (GIS with the Watershed Modeling System (WMS for flood modeling is developed. It also interconnects the terrain models and the GIS software, with commercial standard hydrological and hydraulic models, including HEC-1, HEC-RAS, etc. The Dez River Basin (about 16213 km2 in Khuzestan province, IRAN, is domain of study because of occuring frequent severe flash flooding. As a case of study, a major flood in autumn of 2001 is chosen to examine the modeling framework. The model consists of a rainfall-runoff model (HEC-1 that converts excess precipitation to overland flow and channel runoff and a hydraulic model (HEC-RAS that simulates steady state flow through the river channel network based on the HEC-1, peak hydrographs. In addition, it delineates the maps of potential flood zonation for the Dez River Basin. These are achieved based on the state of the art GIS with using WMS software. Watershed parameters are calibrated manually to perform a good simulation of discharge at three sub-basins. With the calibrated discharge, WMS is capable of producing flood hazard map. The modeling framework presented in this study demonstrates the accuracy and usefulness of the WMS software for flash flooding control. The results of this research will benefit future modeling efforts by providing validate hydrological software to forecast flooding on a regional scale. This model designed for the Dez River Basin, while this regional scale model may be used as a prototype for model applications in other areas.

  8. Spatial Models and Networks of Living Systems

    DEFF Research Database (Denmark)

    Juul, Jeppe Søgaard

    . Such systems are known to be stabilized by spatial structure. Finally, I analyse data from a large mobile phone network and show that people who are topologically close in the network have similar communication patterns. This main part of the thesis is based on six different articles, which I have co...... variables of the system. However, this approach disregards any spatial structure of the system, which may potentially change the behaviour drastically. An alternative approach is to construct a cellular automaton with nearest neighbour interactions, or even to model the system as a complex network...... with interactions defined by network topology. In this thesis I first describe three different biological models of ageing and cancer, in which spatial structure is important for the system dynamics. I then turn to describe characteristics of ecosystems consisting of three cyclically interacting species...

  9. Modelling supervisory controller for hybrid power systems

    Energy Technology Data Exchange (ETDEWEB)

    Pereira, A.; Bindner, H.; Lundsager, P. [Risoe National Lab., Roskilde (Denmark); Jannerup, O. [Technical Univ. of Denmark, Dept. of Automation, Lyngby (Denmark)

    1999-03-01

    Supervisory controllers are important to achieve optimal operation of hybrid power systems. The performance and economics of such systems depend mainly on the control strategy for switching on/off components. The modular concept described in this paper is an attempt to design standard supervisory controllers that could be used in different applications, such as village power and telecommunication applications. This paper presents some basic aspects of modelling and design of modular supervisory controllers using the object-oriented modelling technique. The functional abstraction hierarchy technique is used to formulate the control requirements and identify the functions of the control system. The modular algorithm is generic and flexible enough to be used with any system configuration and several goals (different applications). The modularity includes accepting modification of system configuration and goals during operation with minor or no changes in the supervisory controller. (au)

  10. Decision models in designing flexible production systems

    Directory of Open Access Journals (Sweden)

    Florescu Adriana

    2017-01-01

    Full Text Available Flexible production system is a complex whole that raise some issues in terms of its design and in relation to the conditions for implementing it. To implement a flexible production system configuration must be found that satisfies both economic and system performance requirements. The configuration which best meet the objectives of introducing a flexible production system must be sought in the set of alternatives defined and evaluated. In this paper we present a methodology of realising the configuration and complex evaluation of the analyzed system. It will be developed models which generate new alternative configurations, optimization and evaluation models of the performance of the flexible production system. This will create a framework for interactive decision support, user-oriented that can be used by management to solve this selection problem. The applicative character of the study consist in tracking of the technological process in real time using the developed software package on the designed system, based on mathematical models for configuration and optimization of the system.

  11. Intrinsic Uncertainties in Modeling Complex Systems.

    Energy Technology Data Exchange (ETDEWEB)

    Cooper, Curtis S; Bramson, Aaron L.; Ames, Arlo L.

    2014-09-01

    Models are built to understand and predict the behaviors of both natural and artificial systems. Because it is always necessary to abstract away aspects of any non-trivial system being modeled, we know models can potentially leave out important, even critical elements. This reality of the modeling enterprise forces us to consider the prospective impacts of those effects completely left out of a model - either intentionally or unconsidered. Insensitivity to new structure is an indication of diminishing returns. In this work, we represent a hypothetical unknown effect on a validated model as a finite perturba- tion whose amplitude is constrained within a control region. We find robustly that without further constraints, no meaningful bounds can be placed on the amplitude of a perturbation outside of the control region. Thus, forecasting into unsampled regions is a very risky proposition. We also present inherent difficulties with proper time discretization of models and representing in- herently discrete quantities. We point out potentially worrisome uncertainties, arising from math- ematical formulation alone, which modelers can inadvertently introduce into models of complex systems. Acknowledgements This work has been funded under early-career LDRD project #170979, entitled "Quantify- ing Confidence in Complex Systems Models Having Structural Uncertainties", which ran from 04/2013 to 09/2014. We wish to express our gratitude to the many researchers at Sandia who con- tributed ideas to this work, as well as feedback on the manuscript. In particular, we would like to mention George Barr, Alexander Outkin, Walt Beyeler, Eric Vugrin, and Laura Swiler for provid- ing invaluable advice and guidance through the course of the project. We would also like to thank Steven Kleban, Amanda Gonzales, Trevor Manzanares, and Sarah Burwell for their assistance in managing project tasks and resources.

  12. Hot Water Distribution System Model Enhancements

    Energy Technology Data Exchange (ETDEWEB)

    Hoeschele, M. [Alliance for Residential Building Innovation (ARBI), Davis, CA (United States); Weitzel, E. [Alliance for Residential Building Innovation (ARBI), Davis, CA (United States)

    2012-11-01

    This project involves enhancement of the HWSIM distribution system model to more accurately model pipe heat transfer. Recent laboratory testing efforts have indicated that the modeling of radiant heat transfer effects is needed to accurately characterize piping heat loss. An analytical methodology for integrating radiant heat transfer was implemented with HWSIM. Laboratory test data collected in another project was then used to validate the model for a variety of uninsulated and insulated pipe cases (copper, PEX, and CPVC). Results appear favorable, with typical deviations from lab results less than 8%.

  13. Mathematical Modeling of Hybrid Electrical Engineering Systems

    Directory of Open Access Journals (Sweden)

    A. A. Lobaty

    2016-01-01

    Full Text Available A large class of systems that have found application in various industries and households, electrified transportation facilities and energy sector has been classified as electrical engineering systems. Their characteristic feature is a combination of continuous and discontinuous modes of operation, which is reflected in the appearance of a relatively new term “hybrid systems”. A wide class of hybrid systems is pulsed DC converters operating in a pulse width modulation, which are non-linear systems with variable structure. Using various methods for linearization it is possible to obtain linear mathematical models that rather accurately simulate behavior of such systems. However, the presence in the mathematical models of exponential nonlinearities creates considerable difficulties in the implementation of digital hardware. The solution can be found while using an approximation of exponential functions by polynomials of the first order, that, however, violates the rigor accordance of the analytical model with characteristics of a real object. There are two practical approaches to synthesize algorithms for control of hybrid systems. The first approach is based on the representation of the whole system by a discrete model which is described by difference equations that makes it possible to synthesize discrete algorithms. The second approach is based on description of the system by differential equations. The equations describe synthesis of continuous algorithms and their further implementation in a digital computer included in the control loop system. The paper considers modeling of a hybrid electrical engineering system using differential equations. Neglecting the pulse duration, it has been proposed to describe behavior of vector components in phase coordinates of the hybrid system by stochastic differential equations containing generally non-linear differentiable random functions. A stochastic vector-matrix equation describing dynamics of the

  14. TOWARDS MODELING DISEASE OUTBREAK NOTIFICATION SYSTEMS

    Directory of Open Access Journals (Sweden)

    Farag Azzedin

    2014-06-01

    Full Text Available Disease outbreak detection, monitoring and notification systems play an important role in assessing threats to public health since disease outbreaks are becoming increasingly common world-wide. There are several systems in use around the world, with coverage of national, international and global disease outbreaks. These systems use different taxonomies and classifications for the detection and prioritization of potential disease outbreaks. In this paper, we study and analyze the current disease outbreak systems. Subsequently, we extract features and functions of typical and generic disease outbreak systems. We then propose a generic model for disease outbreak notification systems. Our effort is directed towards standardizing the design process for typical disease outbreak systems.

  15. Modeling Web-based Educational Systems: Process Design Teaching Model

    Directory of Open Access Journals (Sweden)

    Elena Rokou

    2004-01-01

    Full Text Available Using modeling languages is essential to the construction of educational systems based on software engineering principles and methods. Furthermore, the instructional design is undoubtedly the cornerstone of the design and development of educational systems. Although several methodologies and languages have been proposed for the specification of isolated educational multimedia systems, none has optimum results for the description of these systems and, especially, for their pedagogical aspect. Of course this is due primarily to how these systems function and are applied; it is not due to the language itself, although its special characteristics contribute substantially to the development of these systems sometimes positively and sometimes negatively. In this paper, we briefly describe the introduction of stereotypes to the pedagogical design of educational systems and appropriate modifications of the existing package diagrams of UML (Unified Modeling Language. The main objective of these new stereotypes is to describe sufficiently the mechanisms of generation, monitoring and re-adapting of teaching and student’s models which can be used in the educational applications.

  16. Description and implementation of a MiXed Layer model (MXL, v1.0) for the dynamics of the atmospheric boundary layer in the Modular Earth Submodel System (MESSy)

    Science.gov (United States)

    Janssen, R. H. H.; Pozzer, A.

    2015-03-01

    We present a new submodel for the Modular Earth Submodel System (MESSy): the MiXed Layer (MXL) model for the diurnal dynamics of the convective boundary layer, including explicit representations of entrainment and surface fluxes. This submodel is embedded in a new MESSy base model (VERTICO), which represents a single atmospheric column. With the implementation of MXL in MESSy, MXL can be used in combination with other MESSy submodels that represent processes related to atmospheric chemistry. For instance, the coupling of MXL with more advanced modules for gas-phase chemistry (such as the Mainz Isoprene Mechanism 2 (MIM2)), emissions, dry deposition and organic aerosol formation than in previous versions of the MXL code is possible. Since MXL is now integrated in the MESSy framework, it can take advantage of future developments of this framework, such as the inclusion of new process submodels. The coupling of MXL with submodels that represent other processes relevant to chemistry in the atmospheric boundary layer (ABL) yields a computationally inexpensive tool that is ideally suited for the analysis of field data, for evaluating new parametrizations for 3-D models, and for performing systematic sensitivity analyses. A case study for the DOMINO campaign in southern Spain is shown to demonstrate the use and performance of MXL/MESSy in reproducing and analysing field observations.

  17. Spatial Models and Networks of Living Systems

    DEFF Research Database (Denmark)

    Juul, Jeppe Søgaard

    variables of the system. However, this approach disregards any spatial structure of the system, which may potentially change the behaviour drastically. An alternative approach is to construct a cellular automaton with nearest neighbour interactions, or even to model the system as a complex network....... Such systems are known to be stabilized by spatial structure. Finally, I analyse data from a large mobile phone network and show that people who are topologically close in the network have similar communication patterns. This main part of the thesis is based on six different articles, which I have co...

  18. Modelling and Analyses of Embedded Systems Design

    DEFF Research Database (Denmark)

    Brekling, Aske Wiid

    We present the MoVES languages: a language with which embedded systems can be specified at a stage in the development process where an application is identified and should be mapped to an execution platform (potentially multi- core). We give a formal model for MoVES that captures and gives......-based verification is a promising approach for assisting developers of embedded systems. We provide examples of system verifications that, in size and complexity, point in the direction of industrially-interesting systems....

  19. Structure Model of Urban Traffic System Evolution

    Institute of Scientific and Technical Information of China (English)

    JIANG Ke-jin; ZHANG Dian-ye

    2008-01-01

    A structure model of urban traffic system evolution is built based on the analysis of the factors influencing the system evolution and the hierarchy between the factors. Then the influencing degrees of the factors are quantificationally analyzed by DEMATE (decision making trial and evaluation laboratory). The analysis results indicate that the traffic mode structure which achieves the highest central degree is the dominant influencing factor of the urban traffic system evolution, and that economy development and the traffic poficy axe the second important factors that also affect the traffic mode structures. Furthermore, physical geography is a basic restriction to the urban traffic system evolution.

  20. Systems biology and integrative physiological modelling.

    Science.gov (United States)

    Hester, Robert L; Iliescu, Radu; Summers, Richard; Coleman, Thomas G

    2011-03-01

    Over the last 10 years, 'Systems Biology' has focused on the integration of biology and medicine with information technology and computation. The current challenge is to use the discoveries of the last 20 years, such as genomics and proteomics, to develop targeted therapeutical strategies. These strategies are the result of understanding the aetiologies of complex diseases. Scientists predict the data will make personalized medicine rapidly available. However, the data need to be considered as a highly complex system comprising multiple inputs and feedback mechanisms. Translational medicine requires the functional and conceptual linkage of genetics to proteins, proteins to cells, cells to organs, organs to systems and systems to the organism. To help understand the complex integration of these systems, a mathematical model of the entire human body, which accurately links the functioning of all organs and systems together, could provide a framework for the development and testing of new hypotheses that will be important in clinical outcomes. There are several efforts to develop a 'Human Physiome', with the strengths and weaknesses of each being presented here. The development of a 'Human Model', with verification, documentation and validation of the underlying and integrative responses, is essential to provide a usable environment. Future development of a 'Human Model' requires integrative physiologists working in collaboration with other scientists, who have expertise in all areas of human biology, to develop the most accurate and usable human model.

  1. Modeling and Control of Underwater Robotic Systems

    Energy Technology Data Exchange (ETDEWEB)

    Schjoelberg, I:

    1996-12-31

    This doctoral thesis describes modeling and control of underwater vehicle-manipulator systems. The thesis also presents a model and a control scheme for a system consisting of a surface vessel connected to an underwater robotic system by means of a slender marine structure. The equations of motion of the underwater vehicle and manipulator are described and the system kinematics and properties presented. Feedback linearization technique is applied to the system and evaluated through a simulation study. Passivity-based controllers for vehicle and manipulator control are presented. Stability of the closed loop system is proved and simulation results are given. The equation of motion for lateral motion of a cable/riser system connected to a surface vessel at the top end and to a thruster at the bottom end is described and stability analysis and simulations are presented. The equations of motion in 3 degrees of freedom of the cable/riser, surface vessel and robotic system are given. Stability analysis of the total system with PD-controllers is presented. 47 refs., 32 figs., 7 tabs.

  2. Models of cuspy triaxial stellar systems. IV: Rotating systems

    CERN Document Server

    Carpintero, D D

    2016-01-01

    We built two self-consistent models of triaxial, cuspy, rotating stellar systems adding rotation to non-rotating models presented in previous papers of this series. The final angular velocity of the material is not constant and varies with the distance to the center and with the height over the equator of the systems, but the figure rotation is very uniform in both cases. Even though the addition of rotation to the models modifies their original semiaxes ratios, the final rotating models are considerably flattened and triaxial. An analysis of the orbital content of the models shows that about two thirds of their orbits are chaotic yet the models are very stable over intervals of the order of one Hubble time. The bulk of regular orbits are short axis tubes, while long axis tubes are replaced by tubes whose axes lie on the short-long axes plane, but do not coincide with the major axis. Other types of regular orbits that do not appear in non-rotating systems, like horseshoes and orbits that cross themselves, are...

  3. Modeling and Simulation Tools: From Systems Biology to Systems Medicine.

    Science.gov (United States)

    Olivier, Brett G; Swat, Maciej J; Moné, Martijn J

    2016-01-01

    Modeling is an integral component of modern biology. In this chapter we look into the role of the model, as it pertains to Systems Medicine, and the software that is required to instantiate and run it. We do this by comparing the development, implementation, and characteristics of tools that have been developed to work with two divergent methodologies: Systems Biology and Pharmacometrics. From the Systems Biology perspective we consider the concept of "Software as a Medical Device" and what this may imply for the migration of research-oriented, simulation software into the domain of human health.In our second perspective, we see how in practice hundreds of computational tools already accompany drug discovery and development at every stage of the process. Standardized exchange formats are required to streamline the model exchange between tools, which would minimize translation errors and reduce the required time. With the emergence, almost 15 years ago, of the SBML standard, a large part of the domain of interest is already covered and models can be shared and passed from software to software without recoding them. Until recently the last stage of the process, the pharmacometric analysis used in clinical studies carried out on subject populations, lacked such an exchange medium. We describe a new emerging exchange format in Pharmacometrics which covers the non-linear mixed effects models, the standard statistical model type used in this area. By interfacing these two formats the entire domain can be covered by complementary standards and subsequently the according tools.

  4. Cockpit System Situational Awareness Modeling Tool

    Science.gov (United States)

    Keller, John; Lebiere, Christian; Shay, Rick; Latorella, Kara

    2004-01-01

    This project explored the possibility of predicting pilot situational awareness (SA) using human performance modeling techniques for the purpose of evaluating developing cockpit systems. The Improved Performance Research Integration Tool (IMPRINT) was combined with the Adaptive Control of Thought-Rational (ACT-R) cognitive modeling architecture to produce a tool that can model both the discrete tasks of pilots and the cognitive processes associated with SA. The techniques for using this tool to predict SA were demonstrated using the newly developed Aviation Weather Information (AWIN) system. By providing an SA prediction tool to cockpit system designers, cockpit concepts can be assessed early in the design process while providing a cost-effective complement to the traditional pilot-in-the-loop experiments and data collection techniques.

  5. The Red Sea Modeling and Forecasting System

    KAUST Repository

    Hoteit, Ibrahim

    2015-04-01

    Despite its importance for a variety of socio-economical and political reasons and the presence of extensive coral reef gardens along its shores, the Red Sea remains one of the most under-studied large marine physical and biological systems in the global ocean. This contribution will present our efforts to build advanced modeling and forecasting capabilities for the Red Sea, which is part of the newly established Saudi ARAMCO Marine Environmental Research Center at KAUST (SAMERCK). Our Red Sea modeling system compromises both regional and nested costal MIT general circulation models (MITgcm) with resolutions varying between 8 km and 250 m to simulate the general circulation and mesoscale dynamics at various spatial scales, a 10-km resolution Weather Research Forecasting (WRF) model to simulate the atmospheric conditions, a 4-km resolution European Regional Seas Ecosystem Model (ERSEM) to simulate the Red Sea ecosystem, and a 1-km resolution WAVEWATCH-III model to simulate the wind driven surface waves conditions. We have also implemented an oil spill model, and a probabilistic dispersion and larval connectivity modeling system (CMS) based on a stochastic Lagrangian framework and incorporating biological attributes. We are using the models outputs together with available observational data to study all aspects of the Red Sea circulations. Advanced monitoring capabilities are being deployed in the Red Sea as part of the SAMERCK, comprising multiple gliders equipped with hydrographical and biological sensors, high frequency (HF) surface current/wave mapping, buoys/ moorings, etc, complementing the available satellite ocean and atmospheric observations and Automatic Weather Stations (AWS). The Red Sea models have also been equipped with advanced data assimilation capabilities. Fully parallel ensemble-based Kalman filtering (EnKF) algorithms have been implemented with the MITgcm and ERSEM for assimilating all available multivariate satellite and in-situ data sets. We

  6. Functional Risk Modeling for Lunar Surface Systems

    Science.gov (United States)

    Thomson, Fraser; Mathias, Donovan; Go, Susie; Nejad, Hamed

    2010-01-01

    We introduce an approach to risk modeling that we call functional modeling , which we have developed to estimate the capabilities of a lunar base. The functional model tracks the availability of functions provided by systems, in addition to the operational state of those systems constituent strings. By tracking functions, we are able to identify cases where identical functions are provided by elements (rovers, habitats, etc.) that are connected together on the lunar surface. We credit functional diversity in those cases, and in doing so compute more realistic estimates of operational mode availabilities. The functional modeling approach yields more realistic estimates of the availability of the various operational modes provided to astronauts by the ensemble of surface elements included in a lunar base architecture. By tracking functional availability the effects of diverse backup, which often exists when two or more independent elements are connected together, is properly accounted for.

  7. Spatial Database Modeling for Indoor Navigation Systems

    Science.gov (United States)

    Gotlib, Dariusz; Gnat, Miłosz

    2013-12-01

    For many years, cartographers are involved in designing GIS and navigation systems. Most GIS applications use the outdoor data. Increasingly, similar applications are used inside buildings. Therefore it is important to find the proper model of indoor spatial database. The development of indoor navigation systems should utilize advanced teleinformation, geoinformatics, geodetic and cartographical knowledge. The authors present the fundamental requirements for the indoor data model for navigation purposes. Presenting some of the solutions adopted in the world they emphasize that navigation applications require specific data to present the navigation routes in the right way. There is presented original solution for indoor data model created by authors on the basis of BISDM model. Its purpose is to expand the opportunities for use in indoor navigation.

  8. Infectious disease modeling a hybrid system approach

    CERN Document Server

    Liu, Xinzhi

    2017-01-01

    This volume presents infectious diseases modeled mathematically, taking seasonality and changes in population behavior into account, using a switched and hybrid systems framework. The scope of coverage includes background on mathematical epidemiology, including classical formulations and results; a motivation for seasonal effects and changes in population behavior, an investigation into term-time forced epidemic models with switching parameters, and a detailed account of several different control strategies. The main goal is to study these models theoretically and to establish conditions under which eradication or persistence of the disease is guaranteed. In doing so, the long-term behavior of the models is determined through mathematical techniques from switched systems theory. Numerical simulations are also given to augment and illustrate the theoretical results and to help study the efficacy of the control schemes.

  9. The Consumer Health Information System Adoption Model.

    Science.gov (United States)

    Monkman, Helen; Kushniruk, Andre W

    2015-01-01

    Derived from overlapping concepts in consumer health, a consumer health information system refers to any of the broad range of applications, tools, and educational resources developed to empower consumers with knowledge, techniques, and strategies, to manage their own health. As consumer health information systems become increasingly popular, it is important to explore the factors that impact their adoption and success. Accumulating evidence indicates a relationship between usability and consumers' eHealth Literacy skills and the demands consumer HISs place on their skills. Here, we present a new model called the Consumer Health Information System Adoption Model, which depicts both consumer eHealth literacy skills and system demands on eHealth literacy as moderators with the potential to affect the strength of relationship between usefulness and usability (predictors of usage) and adoption, value, and successful use (actual usage outcomes). Strategies for aligning these two moderating factors are described.

  10. Chaos and irreversibility in simple model systems.

    Science.gov (United States)

    Hoover, Wm. G.; Posch, Harald A.

    1998-06-01

    The multifractal link between chaotic time-reversible mechanics and thermodynamic irreversibility is illustrated for three simple chaotic model systems: the Baker Map, the Galton Board, and many-body color conductivity. By scaling time, or the momenta, or the driving forces, it can be shown that the dissipative nature of the three thermostated model systems has analogs in conservative Hamiltonian and Lagrangian mechanics. Links between the microscopic nonequilibrium Lyapunov spectra and macroscopic thermodynamic dissipation are also pointed out. (c) 1998 American Institute of Physics.

  11. Trends in modeling Biomedical Complex Systems

    Directory of Open Access Journals (Sweden)

    Remondini Daniel

    2009-10-01

    Full Text Available Abstract In this paper we provide an introduction to the techniques for multi-scale complex biological systems, from the single bio-molecule to the cell, combining theoretical modeling, experiments, informatics tools and technologies suitable for biological and biomedical research, which are becoming increasingly multidisciplinary, multidimensional and information-driven. The most important concepts on mathematical modeling methodologies and statistical inference, bioinformatics and standards tools to investigate complex biomedical systems are discussed and the prominent literature useful to both the practitioner and the theoretician are presented.

  12. Model-based testing for embedded systems

    CERN Document Server

    Zander, Justyna; Mosterman, Pieter J

    2011-01-01

    What the experts have to say about Model-Based Testing for Embedded Systems: "This book is exactly what is needed at the exact right time in this fast-growing area. From its beginnings over 10 years ago of deriving tests from UML statecharts, model-based testing has matured into a topic with both breadth and depth. Testing embedded systems is a natural application of MBT, and this book hits the nail exactly on the head. Numerous topics are presented clearly, thoroughly, and concisely in this cutting-edge book. The authors are world-class leading experts in this area and teach us well-used

  13. Modeling the Dynamic Digestive System Microbiome

    Directory of Open Access Journals (Sweden)

    Anne M. Estes

    2015-08-01

    Full Text Available “Modeling the Dynamic Digestive System Microbiome” is a hands-on activity designed to demonstrate the dynamics of microbiome ecology using dried pasta and beans to model disturbance events in the human digestive system microbiome. This exercise demonstrates how microbiome diversity is influenced by: 1 niche availability and habitat space and 2 a major disturbance event, such as antibiotic use. Students use a pictorial key to examine prepared models of digestive system microbiomes to determine what the person with the microbiome “ate.” Students then model the effect of taking antibiotics by removing certain “antibiotic sensitive” pasta. Finally, they add in “environmental microbes” or “native microbes” to recolonize the digestive system, determine how resilient their model microbome community is to disturbance, and discuss the implications. Throughout the exercise, students discuss differences in the habitat space available and microbiome community diversity. This exercise can be modified to discuss changes in the microbiome due to diet shifts and the emergence of antibiotic resistance in more depth.

  14. Modelling Inteligent Systems with Level Petri Nets

    Directory of Open Access Journals (Sweden)

    Corina BOCĂNEALĂ

    2008-12-01

    Full Text Available Level Petri Nets are formalism for modeling hierarchical multi-agent system. They are a Petri nets extension, allowing tokens to be nets themselves. This paper is inspired by two classes of level Petri nets: object Petri nets and nested Petri nets. We present some concepts from the artificial intelligence field and we use them to illustrate the modeling power of Petri nets with multi levels.

  15. Complex Systems and Self-organization Modelling

    CERN Document Server

    Bertelle, Cyrille; Kadri-Dahmani, Hakima

    2009-01-01

    The concern of this book is the use of emergent computing and self-organization modelling within various applications of complex systems. The authors focus their attention both on the innovative concepts and implementations in order to model self-organizations, but also on the relevant applicative domains in which they can be used efficiently. This book is the outcome of a workshop meeting within ESM 2006 (Eurosis), held in Toulouse, France in October 2006.

  16. Modelling Coagulation Systems: A Stochastic Approach

    CERN Document Server

    Ryazanov, V V

    2011-01-01

    A general stochastic approach to the description of coagulating aerosol system is developed. As the object of description one can consider arbitrary mesoscopic values (number of aerosol clusters, their size etc). The birth-and-death formalism for a number of clusters can be regarded as a partial case of the generalized storage model. An application of the storage model to the number of monomers in a cluster is discussed.

  17. A Web Interface for Eco System Modeling

    Science.gov (United States)

    McHenry, K.; Kooper, R.; Serbin, S. P.; LeBauer, D. S.; Desai, A. R.; Dietze, M. C.

    2012-12-01

    We have developed the Predictive Ecosystem Analyzer (PEcAn) as an open-source scientific workflow system and ecoinformatics toolbox that manages the flow of information in and out of regional-scale terrestrial biosphere models, facilitates heterogeneous data assimilation, tracks data provenance, and enables more effective feedback between models and field research. The over-arching goal of PEcAn is to make otherwise complex analyses transparent, repeatable, and accessible to a diverse array of researchers, allowing both novice and expert users to focus on using the models to examine complex ecosystems rather than having to deal with complex computer system setup and configuration questions in order to run the models. Through the developed web interface we hide much of the data and model details and allow the user to simply select locations, ecosystem models, and desired data sources as inputs to the model. Novice users are guided by the web interface through setting up a model execution and plotting the results. At the same time expert users are given enough freedom to modify specific parameters before the model gets executed. This will become more important as more and more models are added to the PEcAn workflow as well as more and more data that will become available as NEON comes online. On the backend we support the execution of potentially computationally expensive models on different High Performance Computers (HPC) and/or clusters. The system can be configured with a single XML file that gives it the flexibility needed for configuring and running the different models on different systems using a combination of information stored in a database as well as pointers to files on the hard disk. While the web interface usually creates this configuration file, expert users can still directly edit it to fine tune the configuration.. Once a workflow is finished the web interface will allow for the easy creation of plots over result data while also allowing the user to

  18. Fujisaki Model Based Intonation Modeling for Korean TTS System

    Science.gov (United States)

    Kim, Byeongchang; Lee, Jinsik; Lee, Gary Geunbae

    One of the enduring problems in developing high-quality TTS (text-to-speech) system is pitch contour generation. Considering language specific knowledge, an adjusted Fujisaki model for Korean TTS system is introduced along with refined machine learning features. The results of quantitative and qualitative evaluations show the validity of our system: the accuracy of the phrase command prediction is 0.8928; the correlations of the predicted amplitudes of a phrase command and an accent command are 0.6644 and 0.6002, respectively; our method achieved the level of "fair" naturalness (3.6) in a MOS scale for generated F0 curves.

  19. Analysis of modeling errors in system identification

    Science.gov (United States)

    Hadaegh, F. Y.; Bekey, G. A.

    1986-01-01

    This paper is concerned with the identification of a system in the presence of several error sources. Following some basic definitions, the notion of 'near-equivalence in probability' is introduced using the concept of near-equivalence between a model and process. Necessary and sufficient conditions for the identifiability of system parameters are given. The effect of structural error on the parameter estimates for both deterministic and stochastic cases are considered.

  20. Energy Systems Modelling Research and Analysis

    DEFF Research Database (Denmark)

    Møller Andersen, Frits; Alberg Østergaard, Poul

    2015-01-01

    This editorial introduces the seventh volume of the International Journal of Sustainable Energy Planning and Management. The volume presents part of the outcome of the project Energy Systems Modelling Research and Analysis (ENSYMORA) funded by the Danish Innovation Fund. The project carried out...... by 11 university and industry partners has improved the basis for decision-making within energy planning and energy scenario making by providing new and improved tools and methods for energy systems analyses....

  1. Modelling Driver Assitance Systems by Optimal Control

    OpenAIRE

    Wang, M.; Daamen, W.; Hoogendoorn, S.P.; Van Arem, B.

    2012-01-01

    Driver assistance systems support drivers in operating vehicles in a safe, comfortable and efficient way, and thus may induce changes in traffic flow characteristics. This paper put forward a receding horizon control framework to model driver assistance systems. The accelerations of automated vehicles are determined to optimise a cost function, assuming other vehicles driving at stationary conditions over a prediction horizon. The flexibility of the framework is demonstrated with controller d...

  2. Combustion modeling in advanced gas turbine systems

    Energy Technology Data Exchange (ETDEWEB)

    Smoot, L.D.; Hedman, P.O.; Fletcher, T.H. [Brigham Young Univ., Provo, UT (United States)] [and others

    1995-10-01

    The goal of the U.S. Department of Energy`s Advanced Turbine Systems (ATS) program is to help develop and commercialize ultra-high efficiency, environmentally superior, and cost competitive gas turbine systems for base-load applications in the utility, independent power producer, and industrial markets. Combustion modeling, including emission characteristics, has been identified as a needed, high-priority technology by key professionals in the gas turbine industry.

  3. Improvements in continuum modeling for biomolecular systems

    Science.gov (United States)

    Yu, Qiao; Ben-Zhuo, Lu

    2016-01-01

    Modeling of biomolecular systems plays an essential role in understanding biological processes, such as ionic flow across channels, protein modification or interaction, and cell signaling. The continuum model described by the Poisson- Boltzmann (PB)/Poisson-Nernst-Planck (PNP) equations has made great contributions towards simulation of these processes. However, the model has shortcomings in its commonly used form and cannot capture (or cannot accurately capture) some important physical properties of the biological systems. Considerable efforts have been made to improve the continuum model to account for discrete particle interactions and to make progress in numerical methods to provide accurate and efficient simulations. This review will summarize recent main improvements in continuum modeling for biomolecular systems, with focus on the size-modified models, the coupling of the classical density functional theory and the PNP equations, the coupling of polar and nonpolar interactions, and numerical progress. Project supported by the National Natural Science Foundation of China (Grant No. 91230106) and the Chinese Academy of Sciences Program for Cross & Cooperative Team of the Science & Technology Innovation.

  4. Modeling leaks from liquid hydrogen storage systems.

    Energy Technology Data Exchange (ETDEWEB)

    Winters, William Stanley, Jr.

    2009-01-01

    This report documents a series of models for describing intended and unintended discharges from liquid hydrogen storage systems. Typically these systems store hydrogen in the saturated state at approximately five to ten atmospheres. Some of models discussed here are equilibrium-based models that make use of the NIST thermodynamic models to specify the states of multiphase hydrogen and air-hydrogen mixtures. Two types of discharges are considered: slow leaks where hydrogen enters the ambient at atmospheric pressure and fast leaks where the hydrogen flow is usually choked and expands into the ambient through an underexpanded jet. In order to avoid the complexities of supersonic flow, a single Mach disk model is proposed for fast leaks that are choked. The velocity and state of hydrogen downstream of the Mach disk leads to a more tractable subsonic boundary condition. However, the hydrogen temperature exiting all leaks (fast or slow, from saturated liquid or saturated vapor) is approximately 20.4 K. At these temperatures, any entrained air would likely condense or even freeze leading to an air-hydrogen mixture that cannot be characterized by the REFPROP subroutines. For this reason a plug flow entrainment model is proposed to treat a short zone of initial entrainment and heating. The model predicts the quantity of entrained air required to bring the air-hydrogen mixture to a temperature of approximately 65 K at one atmosphere. At this temperature the mixture can be treated as a mixture of ideal gases and is much more amenable to modeling with Gaussian entrainment models and CFD codes. A Gaussian entrainment model is formulated to predict the trajectory and properties of a cold hydrogen jet leaking into ambient air. The model shows that similarity between two jets depends on the densimetric Froude number, density ratio and initial hydrogen concentration.

  5. Guideliness for system modeling: fault tree [analysis

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Yoon Hwan; Yang, Joon Eon; Kang, Dae Il; Hwang, Mee Jeong

    2004-07-01

    This document, the guidelines for system modeling related to Fault Tree Analysis(FTA), is intended to provide the guidelines with the analyzer to construct the fault trees in the level of the capability category II of ASME PRA standard. Especially, they are to provide the essential and basic guidelines and the related contents to be used in support of revising the Ulchin 3 and 4 PSA model for risk monitor within the capability category II of ASME PRA standard. Normally the main objective of system analysis is to assess the reliability of system modeled by Event Tree Analysis (ETA). A variety of analytical techniques can be used for the system analysis, however, FTA method is used in this procedures guide. FTA is the method used for representing the failure logic of plant systems deductively using AND, OR or NOT gates. The fault tree should reflect all possible failure modes that may contribute to the system unavailability. This should include contributions due to the mechanical failures of the components, Common Cause Failures (CCFs), human errors and outages for testing and maintenance. This document identifies and describes the definitions and the general procedures of FTA and the essential and basic guidelines for reving the fault trees. Accordingly, the guidelines for FTA will be capable to guide the FTA to the level of the capability category II of ASME PRA standard.

  6. Cognitive Systems Modeling and Analysis of Command and Control Systems

    Science.gov (United States)

    Norlander, Arne

    2012-01-01

    Military operations, counter-terrorism operations and emergency response often oblige operators and commanders to operate within distributed organizations and systems for safe and effective mission accomplishment. Tactical commanders and operators frequently encounter violent threats and critical demands on cognitive capacity and reaction time. In the future they will make decisions in situations where operational and system characteristics are highly dynamic and non-linear, i.e. minor events, decisions or actions may have serious and irreversible consequences for the entire mission. Commanders and other decision makers must manage true real time properties at all levels; individual operators, stand-alone technical systems, higher-order integrated human-machine systems and joint operations forces alike. Coping with these conditions in performance assessment, system development and operational testing is a challenge for both practitioners and researchers. This paper reports on research from which the results led to a breakthrough: An integrated approach to information-centered systems analysis to support future command and control systems research development. This approach integrates several areas of research into a coherent framework, Action Control Theory (ACT). It comprises measurement techniques and methodological advances that facilitate a more accurate and deeper understanding of the operational environment, its agents, actors and effectors, generating new and updated models. This in turn generates theoretical advances. Some good examples of successful approaches are found in the research areas of cognitive systems engineering, systems theory, and psychophysiology, and in the fields of dynamic, distributed decision making and naturalistic decision making.

  7. Transforming Graphical System Models to Graphical Attack Models

    DEFF Research Database (Denmark)

    Ivanova, Marieta Georgieva; Probst, Christian W.; Hansen, Rene Rydhof;

    2016-01-01

    Manually identifying possible attacks on an organisation is a complex undertaking; many different factors must be considered, and the resulting attack scenarios can be complex and hard to maintain as the organisation changes. System models provide a systematic representation of organisations that...

  8. Transforming graphical system models to graphical attack models

    NARCIS (Netherlands)

    Ivanova, Marieta Georgieva; Probst, Christian W.; Hansen, René Rydhof; Kammüller, Florian; Mauw, S.; Kordy, B.

    2015-01-01

    Manually identifying possible attacks on an organisation is a complex undertaking; many different factors must be considered, and the resulting attack scenarios can be complex and hard to maintain as the organisation changes. System models provide a systematic representation of organisations that he

  9. Cognitive engineering models in space systems

    Science.gov (United States)

    Mitchell, Christine M.

    1993-01-01

    NASA space systems, including mission operations on the ground and in space, are complex, dynamic, predominantly automated systems in which the human operator is a supervisory controller. Models of cognitive functions in complex systems are needed to describe human performance and form the theoretical basis of operator workstation design, including displays, controls, and decision aids. Currently, there several candidate modeling methodologies. They include the Rasmussen abstraction/aggregation hierarchy and decision ladder, the goal-means network, the problem behavior graph, and the operator function model. The research conducted under the sponsorship of this grant focuses on the extension of the theoretical structure of the operator function model and its application to NASA Johnson mission operations and space station applications. The initial portion of this research consists of two parts. The first is a series of technical exchanges between NASA Johnson and Georgia Tech researchers. The purpose is to identify candidate applications for the current operator function model; prospects include mission operations and the Data Management System Testbed. The second portion will address extensions of the operator function model to tailor it to the specific needs of Johnson applications. At this point, we have accomplished two things. During a series of conversations with JSC researchers, we have defined the technical goal of the research supported by this grant to be the structural definition of the operator function model and its computer implementation, OFMspert. Both the OFM and OFMspert have matured to the point that they require infrastructure to facilitate use by researchers not involved in the evolution of the tools. The second accomplishment this year was the identification of the Payload Deployment and Retrieval System (PDRS) as a candidate system for the case study. In conjunction with government and contractor personnel in the Human-Computer Interaction Lab

  10. Constructing a systems psychodynamic wellness model

    Directory of Open Access Journals (Sweden)

    Sanchen Henning

    2012-01-01

    Full Text Available Orientation: The researchers constructed a Systems Psychodynamic Wellness Model (SPWM by merging theory and concepts from systems psychodynamics and positive psychology. They then refined the model for application in organisations during a Listening Post (LP that comprised experienced subject experts.Research purpose: The purpose of the research was to construct and refine the SPWM in order to understand psychological wellness at the individual, group and organisational levels.Motivation for the study: There is no psychological wellness model that integrates the principles of systems psychodynamics and positive psychology. Systems psychodynamics traditionally focuses on so-called negative behaviour whilst positive psychology tends to idealise positive behaviour. This research tried to merge these views in order to apply them to individual, group and organisational behaviour.Research design, approach and method: The researchers used qualitative, descriptive and conceptual research. They conducted an in-depth literature study to construct the model. They then refined it using the LP.Main findings: The researchers identified 39 themes. They categorised them into three different levels. Three first-level themes emerged as the highest level of integration: identity, hope and love. The nine second-level themes each consisted of three more themes. They were less complex and abstract than the first-level themes. The least complex 27 third-level themes followed.Practical/managerial implications: One can apply the SPWM as a qualitative diagnostic tool for understanding individual, group and organisational wellness and for consulting on systemic wellness.Contribution/value-add: The SPWM offers a model for understanding individual, group and organisational wellness and for consulting on systemic wellness.

  11. Adaptive cyber-attack modeling system

    Science.gov (United States)

    Gonsalves, Paul G.; Dougherty, Edward T.

    2006-05-01

    The pervasiveness of software and networked information systems is evident across a broad spectrum of business and government sectors. Such reliance provides an ample opportunity not only for the nefarious exploits of lone wolf computer hackers, but for more systematic software attacks from organized entities. Much effort and focus has been placed on preventing and ameliorating network and OS attacks, a concomitant emphasis is required to address protection of mission critical software. Typical software protection technique and methodology evaluation and verification and validation (V&V) involves the use of a team of subject matter experts (SMEs) to mimic potential attackers or hackers. This manpower intensive, time-consuming, and potentially cost-prohibitive approach is not amenable to performing the necessary multiple non-subjective analyses required to support quantifying software protection levels. To facilitate the evaluation and V&V of software protection solutions, we have designed and developed a prototype adaptive cyber attack modeling system. Our approach integrates an off-line mechanism for rapid construction of Bayesian belief network (BN) attack models with an on-line model instantiation, adaptation and knowledge acquisition scheme. Off-line model construction is supported via a knowledge elicitation approach for identifying key domain requirements and a process for translating these requirements into a library of BN-based cyber-attack models. On-line attack modeling and knowledge acquisition is supported via BN evidence propagation and model parameter learning.

  12. An interacting systems model of infant habituation.

    Science.gov (United States)

    Sirois, Sylvain; Mareschal, Denis

    2004-10-01

    Habituation and related procedures are the primary behavioral tools used to assess perceptual and cognitive competence in early infancy. This article introduces a neurally constrained computational model of infant habituation. The model combines the two leading process theories of infant habituation into a single functional system that is grounded in functional brain circuitry. The HAB model (for Habituation, Autoassociation, and Brain) proposes that habituation behaviors emerge from the opponent, complementary processes of hippocampal selective inhibition and cortical long-term potentiation. Simulations of a seminal experiment by Fantz [Visual experience in infants: Decreased attention familiar patterns relative to novel ones. Science, 146, 668-670, 1964] are reported. The ability of the model to capture the fine detail of infant data (especially age-related changes in performance) underlines the useful contribution of neurocomputational models to our understanding of behavior in general, and of early cognition in particular.

  13. Statistical Model Checking for Biological Systems

    DEFF Research Database (Denmark)

    David, Alexandre; Larsen, Kim Guldstrand; Legay, Axel

    2014-01-01

    Statistical Model Checking (SMC) is a highly scalable simulation-based verification approach for testing and estimating the probability that a stochastic system satisfies a given linear temporal property. The technique has been applied to (discrete and continuous time) Markov chains, stochastic...... proved very useful for identifying interesting properties of biological systems. Our aim is to offer the best of the two worlds: optimal domain specific interfaces and formalisms suited to biology combined with powerful SMC analysis techniques for stochastic and hybrid systems. This goal is obtained...

  14. Modelling water uptake efficiency of root systems

    Science.gov (United States)

    Leitner, Daniel; Tron, Stefania; Schröder, Natalie; Bodner, Gernot; Javaux, Mathieu; Vanderborght, Jan; Vereecken, Harry; Schnepf, Andrea

    2016-04-01

    Water uptake is crucial for plant productivity. Trait based breeding for more water efficient crops will enable a sustainable agricultural management under specific pedoclimatic conditions, and can increase drought resistance of plants. Mathematical modelling can be used to find suitable root system traits for better water uptake efficiency defined as amount of water taken up per unit of root biomass. This approach requires large simulation times and large number of simulation runs, since we test different root systems under different pedoclimatic conditions. In this work, we model water movement by the 1-dimensional Richards equation with the soil hydraulic properties described according to the van Genuchten model. Climatic conditions serve as the upper boundary condition. The root system grows during the simulation period and water uptake is calculated via a sink term (after Tron et al. 2015). The goal of this work is to compare different free software tools based on different numerical schemes to solve the model. We compare implementations using DUMUX (based on finite volumes), Hydrus 1D (based on finite elements), and a Matlab implementation of Van Dam, J. C., & Feddes 2000 (based on finite differences). We analyse the methods for accuracy, speed and flexibility. Using this model case study, we can clearly show the impact of various root system traits on water uptake efficiency. Furthermore, we can quantify frequent simplifications that are introduced in the modelling step like considering a static root system instead of a growing one, or considering a sink term based on root density instead of considering the full root hydraulic model (Javaux et al. 2008). References Tron, S., Bodner, G., Laio, F., Ridolfi, L., & Leitner, D. (2015). Can diversity in root architecture explain plant water use efficiency? A modeling study. Ecological modelling, 312, 200-210. Van Dam, J. C., & Feddes, R. A. (2000). Numerical simulation of infiltration, evaporation and shallow

  15. Data Model Management for Space Information Systems

    Science.gov (United States)

    Hughes, J. Steven; Crichton, Daniel J.; Ramirez, Paul; Mattmann, chris

    2006-01-01

    The Reference Architecture for Space Information Management (RASIM) suggests the separation of the data model from software components to promote the development of flexible information management systems. RASIM allows the data model to evolve independently from the software components and results in a robust implementation that remains viable as the domain changes. However, the development and management of data models within RASIM are difficult and time consuming tasks involving the choice of a notation, the capture of the model, its validation for consistency, and the export of the model for implementation. Current limitations to this approach include the lack of ability to capture comprehensive domain knowledge, the loss of significant modeling information during implementation, the lack of model visualization and documentation capabilities, and exports being limited to one or two schema types. The advent of the Semantic Web and its demand for sophisticated data models has addressed this situation by providing a new level of data model management in the form of ontology tools. In this paper we describe the use of a representative ontology tool to capture and manage a data model for a space information system. The resulting ontology is implementation independent. Novel on-line visualization and documentation capabilities are available automatically, and the ability to export to various schemas can be added through tool plug-ins. In addition, the ingestion of data instances into the ontology allows validation of the ontology and results in a domain knowledge base. Semantic browsers are easily configured for the knowledge base. For example the export of the knowledge base to RDF/XML and RDFS/XML and the use of open source metadata browsers provide ready-made user interfaces that support both text- and facet-based search. This paper will present the Planetary Data System (PDS) data model as a use case and describe the import of the data model into an ontology tool

  16. Data Model Management for Space Information Systems

    Science.gov (United States)

    Hughes, J. Steven; Crichton, Daniel J.; Ramirez, Paul; Mattmann, chris

    2006-01-01

    The Reference Architecture for Space Information Management (RASIM) suggests the separation of the data model from software components to promote the development of flexible information management systems. RASIM allows the data model to evolve independently from the software components and results in a robust implementation that remains viable as the domain changes. However, the development and management of data models within RASIM are difficult and time consuming tasks involving the choice of a notation, the capture of the model, its validation for consistency, and the export of the model for implementation. Current limitations to this approach include the lack of ability to capture comprehensive domain knowledge, the loss of significant modeling information during implementation, the lack of model visualization and documentation capabilities, and exports being limited to one or two schema types. The advent of the Semantic Web and its demand for sophisticated data models has addressed this situation by providing a new level of data model management in the form of ontology tools. In this paper we describe the use of a representative ontology tool to capture and manage a data model for a space information system. The resulting ontology is implementation independent. Novel on-line visualization and documentation capabilities are available automatically, and the ability to export to various schemas can be added through tool plug-ins. In addition, the ingestion of data instances into the ontology allows validation of the ontology and results in a domain knowledge base. Semantic browsers are easily configured for the knowledge base. For example the export of the knowledge base to RDF/XML and RDFS/XML and the use of open source metadata browsers provide ready-made user interfaces that support both text- and facet-based search. This paper will present the Planetary Data System (PDS) data model as a use case and describe the import of the data model into an ontology tool

  17. A structured and object oriented approach to training system modeling

    OpenAIRE

    Malysheva Elena Yuryevna; Bobrovsky Sergey Michailovich

    2015-01-01

    Structured Analysis and Object Oriented Analysis are widely adopted for system modelling. The article describes the examples of university training system modeling as examples of structured modeling and object-oriented modeling.

  18. Model-based control of networked systems

    CERN Document Server

    Garcia, Eloy; Montestruque, Luis A

    2014-01-01

    This monograph introduces a class of networked control systems (NCS) called model-based networked control systems (MB-NCS) and presents various architectures and control strategies designed to improve the performance of NCS. The overall performance of NCS considers the appropriate use of network resources, particularly network bandwidth, in conjunction with the desired response of the system being controlled.   The book begins with a detailed description of the basic MB-NCS architecture that provides stability conditions in terms of state feedback updates . It also covers typical problems in NCS such as network delays, network scheduling, and data quantization, as well as more general control problems such as output feedback control, nonlinear systems stabilization, and tracking control.   Key features and topics include: Time-triggered and event-triggered feedback updates Stabilization of uncertain systems subject to time delays, quantization, and extended absence of feedback Optimal control analysis and ...

  19. Building a generalized distributed system model

    Science.gov (United States)

    Mukkamala, R.

    1992-01-01

    The key elements in the second year (1991-92) of our project are: (1) implementation of the distributed system prototype; (2) successful passing of the candidacy examination and a PhD proposal acceptance by the funded student; (3) design of storage efficient schemes for replicated distributed systems; and (4) modeling of gracefully degrading reliable computing systems. In the third year of the project (1992-93), we propose to: (1) complete the testing of the prototype; (2) enhance the functionality of the modules by enabling the experimentation with more complex protocols; (3) use the prototype to verify the theoretically predicted performance of locking protocols, etc.; and (4) work on issues related to real-time distributed systems. This should result in efficient protocols for these systems.

  20. Modeling-Enabled Systems Nutritional Immunology

    Directory of Open Access Journals (Sweden)

    Meghna eVerma

    2016-02-01

    Full Text Available This review highlights the fundamental role of nutrition in the maintenance of health, the immune response and disease prevention. Emerging global mechanistic insights in the field of nutritional immunology cannot be gained through reductionist methods alone or by analyzing a single nutrient at a time. We propose to investigate nutritional immunology as a massively interacting system of interconnected multistage and multiscale networks that encompass hidden mechanisms by which nutrition, microbiome, metabolism, genetic predisposition and the immune system interact to delineate health and disease. The review sets an unconventional path to applying complex science methodologies to nutritional immunology research, discovery and development through ‘use cases’ centered around the impact of nutrition on the gut microbiome and immune responses. Our systems nutritional immunology analyses, that include modeling and informatics methodologies in combination with pre-clinical and clinical studies, have the potential to discover emerging systems-wide properties at the interface of the immune system, nutrition, microbiome, and metabolism.

  1. Model based control of refrigeration systems

    Energy Technology Data Exchange (ETDEWEB)

    Sloth Larsen, L.F.

    2005-11-15

    The subject for this Ph.D. thesis is model based control of refrigeration systems. Model based control covers a variety of different types of controls, that incorporates mathematical models. In this thesis the main subject therefore has been restricted to deal with system optimizing control. The optimizing control is divided into two layers, where the system oriented top layers deals with set-point optimizing control and the lower layer deals with dynamical optimizing control in the subsystems. The thesis has two main contributions, i.e. a novel approach for set-point optimization and a novel approach for desynchronization based on dynamical optimization. The focus in the development of the proposed set-point optimizing control has been on deriving a simple and general method, that with ease can be applied on various compositions of the same class of systems, such as refrigeration systems. The method is based on a set of parameter depended static equations describing the considered process. By adapting the parameters to the given process, predict the steady state and computing a steady state gradient of the cost function, the process can be driven continuously towards zero gradient, i.e. the optimum (if the cost function is convex). The method furthermore deals with system constrains by introducing barrier functions, hereby the best possible performance taking the given constrains in to account can be obtained, e.g. under extreme operational conditions. The proposed method has been applied on a test refrigeration system, placed at Aalborg University, for minimization of the energy consumption. Here it was proved that by using general static parameter depended system equations it was possible drive the set-points close to the optimum and thus reduce the power consumption with up to 20%. In the dynamical optimizing layer the idea is to optimize the operation of the subsystem or the groupings of subsystems, that limits the obtainable system performance. In systems

  2. Mars 2020 Model Based Systems Engineering Pilot

    Science.gov (United States)

    Dukes, Alexandra Marie

    2017-01-01

    The pilot study is led by the Integration Engineering group in NASA's Launch Services Program (LSP). The Integration Engineering (IE) group is responsible for managing the interfaces between the spacecraft and launch vehicle. This pilot investigates the utility of Model-Based Systems Engineering (MBSE) with respect to managing and verifying interface requirements. The main objectives of the pilot are to model several key aspects of the Mars 2020 integrated operations and interface requirements based on the design and verification artifacts from Mars Science Laboratory (MSL) and to demonstrate how MBSE could be used by LSP to gain further insight on the interface between the spacecraft and launch vehicle as well as to enhance how LSP manages the launch service. The method used to accomplish this pilot started through familiarization of SysML, MagicDraw, and the Mars 2020 and MSL systems through books, tutorials, and NASA documentation. MSL was chosen as the focus of the model since its processes and verifications translate easily to the Mars 2020 mission. The study was further focused by modeling specialized systems and processes within MSL in order to demonstrate the utility of MBSE for the rest of the mission. The systems chosen were the In-Flight Disconnect (IFD) system and the Mass Properties process. The IFD was chosen as a system of focus since it is an interface between the spacecraft and launch vehicle which can demonstrate the usefulness of MBSE from a system perspective. The Mass Properties process was chosen as a process of focus since the verifications for mass properties occur throughout the lifecycle and can demonstrate the usefulness of MBSE from a multi-discipline perspective. Several iterations of both perspectives have been modeled and evaluated. While the pilot study will continue for another 2 weeks, pros and cons of using MBSE for LSP IE have been identified. A pro of using MBSE includes an integrated view of the disciplines, requirements, and

  3. Packet models revisited: tandem and priority systems

    NARCIS (Netherlands)

    Mandjes, M.R.H.

    2004-01-01

    We examine two extensions of traditional single-node packet-scale queueing models: tandem networks and (strict) priority systems. Two generic input processes are considered: periodic and Poisson arrivals. For the two-node tandem, an exact expression is derived for the joint distribution of the total

  4. Packet models revisited: tandem and priority systems

    NARCIS (Netherlands)

    M.R.H. Mandjes

    2004-01-01

    Abstract : We examine two extensions of traditional single-node packet-scale queueing models: tandem networks and (strict) priority systems. Two generic input processes are considered: periodic and Poisson arrivals. For the two-node tandem, an exact expression is derived for the joint distribution o

  5. Quantitative system validation in model driven design

    DEFF Research Database (Denmark)

    Hermanns, Hilger; Larsen, Kim Guldstrand; Raskin, Jean-Francois;

    2010-01-01

    The European STREP project Quasimodo1 develops theory, techniques and tool components for handling quantitative constraints in model-driven development of real-time embedded systems, covering in particular real-time, hybrid and stochastic aspects. This tutorial highlights the advances made, focus...

  6. Modelling energy systems for developing countries

    NARCIS (Netherlands)

    Urban, F.; Benders, R.M.J.; Moll, H.C.

    2007-01-01

    Developing countries' energy use is rapidly increasing, which affects global climate change and global and regional energy settings. Energy models are helpful for exploring the future of developing and industrialised countries. However, energy systems of developing countries differ from those of ind

  7. Energy Systems Modelling Research and Analysis

    DEFF Research Database (Denmark)

    Møller Andersen, Frits; Alberg Østergaard, Poul

    2015-01-01

    This editorial introduces the seventh volume of the International Journal of Sustainable Energy Planning and Management. The volume presents part of the outcome of the project Energy Systems Modelling Research and Analysis (ENSYMORA) funded by the Danish Innovation Fund. The project carried out...

  8. Integrated Model of Bioenergy and Agriculture System

    DEFF Research Database (Denmark)

    Sigurjonsson, Hafthor Ægir; Elmegaard, Brian; Clausen, Lasse Røngaard

    2015-01-01

    approach that builds on Life Cycle Inventory and carries out Life Cycle Impact Assessment for a con- sequential Life Cycle Assessment on integrated bioenergy and agriculture systems. The model framework is built in Python which connects various freely available soft- ware that handle different aspects...

  9. Modeling and simulation for RF system design

    CERN Document Server

    Frevert, Ronny; Jancke, Roland; Knöchel, Uwe; Schwarz, Peter; Kakerow, Ralf; Darianian, Mohsen

    2005-01-01

    Focusing on RF specific modeling and simulation methods, and system and circuit level descriptions, this work contains application-oriented training material. Accompanied by a CD- ROM, it combines the presentation of a mixed-signal design flow, an introduction into VHDL-AMS and Verilog-A, and the application of commercially available simulators.

  10. Systems modelling for effective mine water management

    Energy Technology Data Exchange (ETDEWEB)

    Cote, C.M.; Moran, C.J.; Hedemann, C.J.; Koch, C. [University of Queensland, Brisbane, Qld. (Australia)

    2010-12-15

    Concerns about the difficulties in securing water have led the Australian coal mining industry to seek innovative ways to improve its water management and to adopt novel strategies that will lead to less water being used and more water being reused. Simulation tools are essential to assess current water management performance and to predict the efficiency of potential strategies. As water systems on coal mines are complex and consist of various inter-connected elements, a systems approach was selected, which views mine site water management as a system that obtains water from various sources (surface, groundwater), provides sufficient water of suitable quality to the mining tasks (coal beneficiation, dust suppression, underground operations) and maintains environmental performance. In this paper, the model is described and its calibration is illustrated. The results of applying the model for the comparison of the water balances of 7 coal mines in the northern Bowen Basin (Queensland, Australia) are presented. The model is used to assess the impact of applying specific water management strategies. Results show that a simple systems model is an appropriate tool for assessing site performance, for providing guidance to improve performance through strategic planning, and for guiding adoption of site objectives.

  11. Formal Modeling and Analysis of Timed Systems

    DEFF Research Database (Denmark)

    Larsen, Kim Guldstrand; Niebert, Peter

    This book constitutes the thoroughly refereed post-proceedings of the First International Workshop on Formal Modeling and Analysis of Timed Systems, FORMATS 2003, held in Marseille, France in September 2003. The 19 revised full papers presented together with an invited paper and the abstracts...

  12. Control Architecture Modeling for Future Power Systems

    DEFF Research Database (Denmark)

    Heussen, Kai

    and operation structures; and finally the application to some concrete study cases, including a present system balancing, and proposed control structures such as Microgrids and Cells. In the second part, the main contributions are the outline of a formation strategy, integrating the design and model...

  13. Research in Adaptronic Automatic Control System and Biosensor System Modelling

    Directory of Open Access Journals (Sweden)

    Skopis Vladimir

    2015-07-01

    Full Text Available This paper describes the research on adaptronic systems made by the author and offers to use biosensors that can be later inserted into the adaptronic systems. Adaptronic systems are based, on the one hand, on the adaptronic approach when the system is designed not to always meet the worst condition, but to change the structure of the system according to the external conditions. On the other hand, it is an extension of common automatic control ad adaptive systems. So, in the introduction firstly the adaptronic approach and biosensor as a term is explained. Adaptive systems, upon which adaptronic ones are based, are also mentioned. Then the construction of biosensor is described, as well as some information is given about the classification of biosensors and their main groups. Also it is suggested to use lichen indicators in industry to control concentration of chemical substances in the air. After that mathematical models and computer experiments for adaptronic system and biosensor analysis are given.

  14. Parameter optimization in S-system models

    Directory of Open Access Journals (Sweden)

    Vasconcelos Ana

    2008-04-01

    Full Text Available Abstract Background The inverse problem of identifying the topology of biological networks from their time series responses is a cornerstone challenge in systems biology. We tackle this challenge here through the parameterization of S-system models. It was previously shown that parameter identification can be performed as an optimization based on the decoupling of the differential S-system equations, which results in a set of algebraic equations. Results A novel parameterization solution is proposed for the identification of S-system models from time series when no information about the network topology is known. The method is based on eigenvector optimization of a matrix formed from multiple regression equations of the linearized decoupled S-system. Furthermore, the algorithm is extended to the optimization of network topologies with constraints on metabolites and fluxes. These constraints rejoin the system in cases where it had been fragmented by decoupling. We demonstrate with synthetic time series why the algorithm can be expected to converge in most cases. Conclusion A procedure was developed that facilitates automated reverse engineering tasks for biological networks using S-systems. The proposed method of eigenvector optimization constitutes an advancement over S-system parameter identification from time series using a recent method called Alternating Regression. The proposed method overcomes convergence issues encountered in alternate regression by identifying nonlinear constraints that restrict the search space to computationally feasible solutions. Because the parameter identification is still performed for each metabolite separately, the modularity and linear time characteristics of the alternating regression method are preserved. Simulation studies illustrate how the proposed algorithm identifies the correct network topology out of a collection of models which all fit the dynamical time series essentially equally well.

  15. Size and complexity in model financial systems.

    Science.gov (United States)

    Arinaminpathy, Nimalan; Kapadia, Sujit; May, Robert M

    2012-11-06

    The global financial crisis has precipitated an increasing appreciation of the need for a systemic perspective toward financial stability. For example: What role do large banks play in systemic risk? How should capital adequacy standards recognize this role? How is stability shaped by concentration and diversification in the financial system? We explore these questions using a deliberately simplified, dynamic model of a banking system that combines three different channels for direct transmission of contagion from one bank to another: liquidity hoarding, asset price contagion, and the propagation of defaults via counterparty credit risk. Importantly, we also introduce a mechanism for capturing how swings in "confidence" in the system may contribute to instability. Our results highlight that the importance of relatively large, well-connected banks in system stability scales more than proportionately with their size: the impact of their collapse arises not only from their connectivity, but also from their effect on confidence in the system. Imposing tougher capital requirements on larger banks than smaller ones can thus enhance the resilience of the system. Moreover, these effects are more pronounced in more concentrated systems, and continue to apply, even when allowing for potential diversification benefits that may be realized by larger banks. We discuss some tentative implications for policy, as well as conceptual analogies in ecosystem stability and in the control of infectious diseases.

  16. Size and complexity in model financial systems

    Science.gov (United States)

    Arinaminpathy, Nimalan; Kapadia, Sujit; May, Robert M.

    2012-01-01

    The global financial crisis has precipitated an increasing appreciation of the need for a systemic perspective toward financial stability. For example: What role do large banks play in systemic risk? How should capital adequacy standards recognize this role? How is stability shaped by concentration and diversification in the financial system? We explore these questions using a deliberately simplified, dynamic model of a banking system that combines three different channels for direct transmission of contagion from one bank to another: liquidity hoarding, asset price contagion, and the propagation of defaults via counterparty credit risk. Importantly, we also introduce a mechanism for capturing how swings in “confidence” in the system may contribute to instability. Our results highlight that the importance of relatively large, well-connected banks in system stability scales more than proportionately with their size: the impact of their collapse arises not only from their connectivity, but also from their effect on confidence in the system. Imposing tougher capital requirements on larger banks than smaller ones can thus enhance the resilience of the system. Moreover, these effects are more pronounced in more concentrated systems, and continue to apply, even when allowing for potential diversification benefits that may be realized by larger banks. We discuss some tentative implications for policy, as well as conceptual analogies in ecosystem stability and in the control of infectious diseases. PMID:23091020

  17. Improving models for urban soundscape systems

    Directory of Open Access Journals (Sweden)

    Lawrence Harvey

    2013-12-01

    Full Text Available Large-scale urban soundscape systems offer novel environments for electroacoustic composers, sound artists and sound designers to extend their practice beyond concert halls, art galleries and screen-based digital media. One such system with 156 loudspeakers was installed in 1991 on the Southgate Arts and Leisure Precinct in central Melbourne. Over the next 15 years another three large multichannel soundscape systems were installed on other sites close to the first. A fifth system was established for a single work of art in 2006. Despite this private and public investment in sound art estimated at over one million Australian dollars, several systems are no longer in operation while some remaining systems require technical and curatorial development to ensure their continued cultural presence. To investigate why some systems had failed, interviews were conducted with key players in the development and operation of the five systems. A report from the interviews was produced and is the basis of this paper framing critical issues for improving models of urban soundscape practice. Following a brief overview of related studies in urban sound practices, and descriptions of the system and original study, key themes that emerged from the interviews are examined.

  18. Engineering design of systems models and methods

    CERN Document Server

    Buede, Dennis M

    2009-01-01

    The ideal introduction to the engineering design of systems-now in a new edition. The Engineering Design of Systems, Second Edition compiles a wealth of information from diverse sources to provide a unique, one-stop reference to current methods for systems engineering. It takes a model-based approach to key systems engineering design activities and introduces methods and models used in the real world. Features new to this edition include: * The addition of Systems Modeling Language (SysML) to several of the chapters, as well as the introduction of new terminology * Additional material on partitioning functions and components * More descriptive material on usage scenarios based on literature from use case development * Updated homework assignments * The software product CORE (from Vitech Corporation) is used to generate the traditional SE figures and the software product MagicDraw UML with SysML plugins (from No Magic, Inc.) is used for the SysML figures This book is designed to be an introductory reference ...

  19. Lit appearance modeling of illumination systems

    Science.gov (United States)

    Koshel, R. John

    2002-09-01

    In illumination systems the look and feel are often more important than objective criterion, such as uniformity and efficiency. The reason for this is two fold: the lit appearance often sells an item and substantial variation in the illumination distribution (up to 50%) over a broad region is not noticeable to an observer. Therefore, subjective criterion, such as the lit appearance, typically plays a crucial role in the development of an illumination system. Additionally, by using computer models to ascertain the lit appearance before manufacture of the system, it allows the designer to modify the system while not demanding investment to produce prototypes. I discuss methods of determining the lit appearance for illumination systems. This modeling includes the inclusion of material and surface properties, such as surface finish, spectral transmission, and internal scattering; the response of the human eye; and the amount of rays that must be traced. By archiving the ray data, animations as a function of position and angle can be developed. Examples are developed to highlight the utility of this technique. These examples include taillights for the automotive industry and a backlit LCD screen for a laptop. Animations of these models demonstrate their luminance.

  20. Modeling delayed processes in biological systems

    Science.gov (United States)

    Feng, Jingchen; Sevier, Stuart A.; Huang, Bin; Jia, Dongya; Levine, Herbert

    2016-09-01

    Delayed processes are ubiquitous in biological systems and are often characterized by delay differential equations (DDEs) and their extension to include stochastic effects. DDEs do not explicitly incorporate intermediate states associated with a delayed process but instead use an estimated average delay time. In an effort to examine the validity of this approach, we study systems with significant delays by explicitly incorporating intermediate steps. We show that such explicit models often yield significantly different equilibrium distributions and transition times as compared to DDEs with deterministic delay values. Additionally, different explicit models with qualitatively different dynamics can give rise to the same DDEs revealing important ambiguities. We also show that DDE-based predictions of oscillatory behavior may fail for the corresponding explicit model.