无
2010-01-01
China[Guangzheu] International Trade Fair for Home Textiles Date:March 18th- March 21st,2011 Venue:China Import and Export Fair Complex（Guangzhou,China） Organizers:China National Textile&Apparel Council China Foreign Trade Center（Group） China Home Textile Association China Foreign Trade Guangzhou Exhibition Corp.
Staff Association
2017-01-01
A Look of Hope Islam Mahmoud Sweity From 19 to 30 June 2017 CERN Meyrin, Main Building Islam Mahmoud Sweity Islam Mahmoud Sweity was born in 1997 at Beit Awwa, Palestine. She is currently following a course to get an Art diploma of Painting at the college of Fine Arts at An-Najah National University under the supervision of Esmat Al As'aad. Her portraits, landscapes and still life paintings are full of life and shining colours. Charged of emotional empathy they catch the attention of the viewer and are reminding us that life is beautiful and worth living in spite of all difficulties we have to go through. She participated in many exhibitions and has exposed her drawings in 2015 at CERN and in France in the framework of the exhibition "The Origin“, and in 2017 in the Former Yugoslav Republic of Macedonia, Palestina and Jordan. In this exhibition the oil paintings made in the past year will be presented. For more information : staff.association@cern.ch | T&eacu...
Staff Association
2016-01-01
Encounters Hanne Blitz From February 1st to 12th 2016 CERN Meyrin, Main Building What is our reaction to a first encounter with a tourist attraction? Contemporary Dutch painter Hanne Blitz captures visitors' responses to art and architecture, sweeping vistas and symbolic memorials. Encounters, a series of oil paintings curated specially for this CERN exhibition, depicts tourists visiting cultural highlights around the world. A thought-provoking journey not to be missed, and a tip of the hat to CERN's large Hadron Collider.
Staff Association
2017-01-01
Sintropie Flavio Pellegrini From 13 to 24 March 2017 CERN Meyrin, Main Building Energia imprigionata - Flavio Pellegrini. The exhibition is composed by eleven wood artworks with the expression of movement as theme. The artworks are the result of harmonics math applied to sculpture. The powerful black colour is dominated by the light source, generating reflexes and modulations. The result is a continuous variation of perspective visions. The works generate, at a first approach, an emotion of mystery and incomprehension, only a deeper contemplation lets one discover entangling and mutative details, evidencing the elegance of the lines and letting the meaning emerge. For more information : staff.association@cern.ch | Tél: 022 766 37 38
A content-oriented model for science exhibit engineering
Achiam, Marianne
2013-01-01
: as a means to operationalize the link between exhibit features and visitor activities; and as a template to transform scientists’ practices in the research context into visitors’ activities in the exhibit context. The resulting model of science exhibit engineering is presented and exemplified, and its...... in prompting visitors to carry out intended actions, exhibits do not necessarily promote the intended interpretations of these actions among visitors. Here, the notion of praxeology from didactics research is suggested as a model to remedy this shortcoming. The suggested role of praxeology is twofold......Recently, science museums have begun to review their educational purposes and redesign their pedagogies. At the most basic level, this entails accounting for the performance of individual exhibits, and indeed, in some cases, research indicates shortcomings in exhibit design: While often successful...
Magnetization direction in the Heisenberg model exhibiting fractional Brownian motion
Zhang, Zhengping; Mouritsen, Ole G.; Zuckermann, Martin J.
1993-01-01
The temporal magnetization-direction fluctuations in the three-dimensional classical ferromagnetic Heisenberg model have been generated by Monte Carlo simulation and analyzed by the rescaled-range method to yield the Hurst exponent H. A value of H congruent-to 1 has been found to apply...
Rossetti, Manuel D
2015-01-01
Emphasizes a hands-on approach to learning statistical analysis and model building through the use of comprehensive examples, problems sets, and software applications With a unique blend of theory and applications, Simulation Modeling and Arena®, Second Edition integrates coverage of statistical analysis and model building to emphasize the importance of both topics in simulation. Featuring introductory coverage on how simulation works and why it matters, the Second Edition expands coverage on static simulation and the applications of spreadsheets to perform simulation. The new edition als
A Social Network Model Exhibiting Tunable Overlapping Community Structure
Liu, D.; Blenn, N.; Van Mieghem, P.F.A.
2012-01-01
Social networks, as well as many other real-world networks, exhibit overlapping community structure. In this paper, we present formulas which facilitate the computation for characterizing the overlapping community structure of networks. A hypergraph representation of networks with overlapping
Computer Modeling and Simulation
Pronskikh, V. S. [Fermilab
2014-05-09
Verification and validation of computer codes and models used in simulation are two aspects of the scientific practice of high importance and have recently been discussed by philosophers of science. While verification is predominantly associated with the correctness of the way a model is represented by a computer code or algorithm, validation more often refers to model’s relation to the real world and its intended use. It has been argued that because complex simulations are generally not transparent to a practitioner, the Duhem problem can arise for verification and validation due to their entanglement; such an entanglement makes it impossible to distinguish whether a coding error or model’s general inadequacy to its target should be blamed in the case of the model failure. I argue that in order to disentangle verification and validation, a clear distinction between computer modeling (construction of mathematical computer models of elementary processes) and simulation (construction of models of composite objects and processes by means of numerical experimenting with them) needs to be made. Holding on to that distinction, I propose to relate verification (based on theoretical strategies such as inferences) to modeling and validation, which shares the common epistemology with experimentation, to simulation. To explain reasons of their intermittent entanglement I propose a weberian ideal-typical model of modeling and simulation as roles in practice. I suggest an approach to alleviate the Duhem problem for verification and validation generally applicable in practice and based on differences in epistemic strategies and scopes
Theory Modeling and Simulation
Shlachter, Jack [Los Alamos National Laboratory
2012-08-23
Los Alamos has a long history in theory, modeling and simulation. We focus on multidisciplinary teams that tackle complex problems. Theory, modeling and simulation are tools to solve problems just like an NMR spectrometer, a gas chromatograph or an electron microscope. Problems should be used to define the theoretical tools needed and not the other way around. Best results occur when theory and experiments are working together in a team.
Modelling the equilibrium bed topography of submarine meanders that exhibit reversed secondary flows
Darby, Stephen E.; Peakall, Jeff
2012-08-01
Submarine meandering channels formed by turbidity currents are common; however, their location on the ocean floor and their inactive status make it difficult to measure process dynamics and bed morphology. Conceptual models have, therefore, instead been developed by analogy with the well understood mechanics of fluvial bends. However, unlike fluvial currents, in turbidity currents the downstream velocity maximum typically occurs near the bed and recent experimental and theoretical studies suggest that, under certain hydraulic and morphological conditions, this forces the secondary flow to exhibit the reverse sense to that encountered in fluvial bends. Herein the possible morphological implications of a reversal of secondary flow are explored by modelling the force balance on sediment grains moving through either (i) field and laboratory submarine meander bends that are known to exhibit ‘reversed' secondary flows, or (ii) inactive submarine meander bends where the nature of the secondary flow in the formative turbidity currents can be inferred to be reversed. Exploratory simulations are undertaken for a single hypothetical submarine bend with morphological properties based on nine relic meanders observed on the floor of the Gulf of Alaska. Reconstructions of secondary flow properties within the Gulf of Alaska bends indicate that they likely exhibited reversed secondary flows. Results of the exploratory simulations indicate that, unlike typical fluvial meanders, the transverse bed profile gradient of the hypothetical bend is very low and the point bar is located downstream of the bend apex.
Simulation modeling of carcinogenesis.
Ellwein, L B; Cohen, S M
1992-03-01
A discrete-time simulation model of carcinogenesis is described mathematically using recursive relationships between time-varying model variables. The dynamics of cellular behavior is represented within a biological framework that encompasses two irreversible and heritable genetic changes. Empirical data and biological supposition dealing with both control and experimental animal groups are used together to establish values for model input variables. The estimation of these variables is integral to the simulation process as described in step-by-step detail. Hepatocarcinogenesis in male F344 rats provides the basis for seven modeling scenarios which illustrate the complexity of relationships among cell proliferation, genotoxicity, and tumor risk.
Casetti, E.; Vogt, W.G.; Mickle, M.H.
1984-01-01
This conference includes papers on the uses of supercomputers, multiprocessors, artificial intelligence and expert systems in various energy applications. Topics considered include knowledge-based expert systems for power engineering, a solar air conditioning laboratory computer system, multivariable control systems, the impact of power system disturbances on computer systems, simulating shared-memory parallel computers, real-time image processing with multiprocessors, and network modeling and simulation of greenhouse solar systems.
Validation of simulation models
Rehman, Muniza; Pedersen, Stig Andur
2012-01-01
In philosophy of science, the interest for computational models and simulations has increased heavily during the past decades. Different positions regarding the validity of models have emerged but the views have not succeeded in capturing the diversity of validation methods. The wide variety...... of models has been somewhat narrow-minded reducing the notion of validation to establishment of truth. This article puts forward the diversity in applications of simulation models that demands a corresponding diversity in the notion of validation....... of models with regards to their purpose, character, field of application and time dimension inherently calls for a similar diversity in validation approaches. A classification of models in terms of the mentioned elements is presented and used to shed light on possible types of validation leading...
Larsen, Gunner Chr.; Madsen Aagaard, Helge; Larsen, Torben J.;
, have the potential to include also mutual wake interaction phenomenons. The basic conjecture behind the dynamic wake meandering (DWM) model is that wake transportation in the atmospheric boundary layer is driven by the large scale lateral- and vertical turbulence components. Based on this conjecture...... and trailed vorticity, has been approached by a simple semi-empirical model essentially based on an eddy viscosity philosophy. Contrary to previous attempts to model wake loading, the DWM approach opens for a unifying description in the sense that turbine power- and load aspects can be treated simultaneously...... methodology has been implemented in the aeroelastic code HAWC2, and example simulations of wake situations, from the small Tjæreborg wind farm, have been performed showing satisfactory agreement between predictions and measurements...
Stochastic Model of Gap Junctions Exhibiting Rectification and Multiple Closed States of Slow Gates.
Snipas, Mindaugas; Kraujalis, Tadas; Paulauskas, Nerijus; Maciunas, Kestutis; Bukauskas, Feliksas F
2016-03-29
Gap-junction (GJ) channels formed from connexin (Cx) proteins provide direct pathways for electrical and metabolic cell-cell communication. Earlier, we developed a stochastic 16-state model (S16SM) of voltage gating of the GJ channel containing two pairs of fast and slow gates, each operating between open (o) and closed (c) states. However, experimental data suggest that gates may in fact contain two or more closed states. We developed a model in which the slow gate operates according to a linear reaction scheme, o↔c1↔c2, where c1 and c2 are initial-closed and deep-closed states that both close the channel fully, whereas the fast gate operates between the open state and the closed state and exhibits a residual conductance. Thus, we developed a stochastic 36-state model (S36SM) of GJ channel gating that is sensitive to transjunctional voltage (Vj). To accelerate simulation and eliminate noise in simulated junctional conductance (gj) records, we transformed an S36SM into a Markov chain 36-state model (MC36SM) of GJ channel gating. This model provides an explanation for well-established experimental data, such as delayed gj recovery after Vj gating, hysteresis of gj-Vj dependence, and the low ratio of functional channels to the total number of GJ channels clustered in junctional plaques, and it has the potential to describe chemically mediated gating, which cannot be reflected using an S16SM. The MC36SM, when combined with global optimization algorithms, can be used for automated estimation of gating parameters including probabilities of c1↔c2 transitions from experimental gj-time and gj-Vj dependencies.
Puerto Rico Univ., San Juan. School of Dentistry.
This annex supplements the Puerto Rico Experimental Model Dental Training Program Comprehensive Report (CE 028 213) and is comprised of exhibits A through F. Among the information included in the exhibits is the experimental model schedule, the schematic representation, the content display, and the course outlines for all courses in the program.…
Delay modeling in logic simulation
Acken, J. M.; Goldstein, L. H.
1980-01-01
As digital integrated circuit size and complexity increases, the need for accurate and efficient computer simulation increases. Logic simulators such as SALOGS (SAndia LOGic Simulator), which utilize transition states in addition to the normal stable states, provide more accurate analysis than is possible with traditional logic simulators. Furthermore, the computational complexity of this analysis is far lower than that of circuit simulation such as SPICE. An eight-value logic simulation environment allows the use of accurate delay models that incorporate both element response and transition times. Thus, timing simulation with an accuracy approaching that of circuit simulation can be accomplished with an efficiency comparable to that of logic simulation. 4 figures.
Preparations, models, and simulations.
Rheinberger, Hans-Jörg
2015-01-01
This paper proposes an outline for a typology of the different forms that scientific objects can take in the life sciences. The first section discusses preparations (or specimens)--a form of scientific object that accompanied the development of modern biology in different guises from the seventeenth century to the present: as anatomical-morphological specimens, as microscopic cuts, and as biochemical preparations. In the second section, the characteristics of models in biology are discussed. They became prominent from the end of the nineteenth century onwards. Some remarks on the role of simulations--characterising the life sciences of the turn from the twentieth to the twenty-first century--conclude the paper.
Puerto Rico Univ., San Juan. School of Dentistry.
This annex supplements the Puerto Rico Experimental Model Dental Training Program Comprehensive Report (CE 028 213) and is comprised of exhibits G through L. Among the information included in the exhibits is the evaluation reports of the commission on accreditation, the detailed curriculum, and the accredited program's scope, sequence, and course…
Lunar soil simulant and synthesized nanoparticles of magnetite exhibit diverse neurotoxic potential
Borisova, Tatiana; Krisanova, Natalia; Sivko, Roman; Nazarova, Anastasiya; Borysov, Arseniy
Lunar soli simulant can be deleterious to human physiology and the components of lunar soil may be internalized by lung epithelium and may overcome the blood-brain barrier. Nanoparticles of ferric oxide are one of the components of Lunar soil simulants. Neurotoxic potential of lunar soil simulant and synthesized nanoparticles of magnetite was analyzed. The size of particles, their effects on membrane potential, acidification of synaptic vesicles, uptake and ambient level of glutamate, which is the major excitatory neurotransmitter in the CNS, were studied in isolated rat brain nerve terminals (synaptosomes) using photon correlation spectroscopy, spectrofluorimetry, radiolabeled assay, respectively. No significant effect of Lunar soil simulant and synthesized nanoparticles of magnetite on acidification of synaptic vesicles were found in synaptosomes. Also, nanoparticles did not influence the potential of the plasma membrane of synaptosomes. Unspecific binding of L-[14C]glutamate to synaptosomes was not altered by nanoparticles of magnetite, whereas in the presence of Lunar soil simulant this parameter was changed. Thus, it was suggested that Lunar soil simulant might disturb glutamate homeostasis in the mammalian CNS.
Mortensen, Marianne Foss
) a synthesis of the findings from the first two studies with findings from the literature to generate two types of results: a coherent series of suggestions for a design iteration of the studied exhibit as well as a more general normative model for exhibit engineering. Finally, another perspective...
Notes on modeling and simulation
Redondo, Antonio [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
2017-03-10
These notes present a high-level overview of how modeling and simulation are carried out by practitioners. The discussion is of a general nature; no specific techniques are examined but the activities associated with all modeling and simulation approaches are briefly addressed. There is also a discussion of validation and verification and, at the end, a section on why modeling and simulation are useful.
Modeling and simulation with operator scaling
Cohen, Serge; Rosinski, Jan
2009-01-01
Self-similar processes are useful in modeling diverse phenomena that exhibit scaling properties. Operator scaling allows a different scale factor in each coordinate. This paper develops practical methods for modeling and simulating stochastic processes with operator scaling. A simulation method for operator stable Levy processes is developed, based on a series representation, along with a Gaussian approximation of the small jumps. Several examples are given to illustrate practical applications. A classification of operator stable Levy processes in two dimensions is provided according to their exponents and symmetry groups. We conclude with some remarks and extensions to general operator self-similar processes.
Evaluating uncertainty in simulation models
McKay, M.D.; Beckman, R.J.; Morrison, J.D.; Upton, S.C.
1998-12-01
The authors discussed some directions for research and development of methods for assessing simulation variability, input uncertainty, and structural model uncertainty. Variance-based measures of importance for input and simulation variables arise naturally when using the quadratic loss function of the difference between the full model prediction y and the restricted prediction {tilde y}. The concluded that generic methods for assessing structural model uncertainty do not now exist. However, methods to analyze structural uncertainty for particular classes of models, like discrete event simulation models, may be attainable.
Simulation Model of a Transient
Jauch, Clemens; Sørensen, Poul; Bak-Jensen, Birgitte
2005-01-01
This paper describes the simulation model of a controller that enables an active-stall wind turbine to ride through transient faults. The simulated wind turbine is connected to a simple model of a power system. Certain fault scenarios are specified and the turbine shall be able to sustain operation...... in case of such faults. The design of the controller is described and its performance assessed by simulations. The control strategies are explained and the behaviour of the turbine discussed....
Simulation Model of a Transient
Jauch, Clemens; Sørensen, Poul; Bak-Jensen, Birgitte
2005-01-01
This paper describes the simulation model of a controller that enables an active-stall wind turbine to ride through transient faults. The simulated wind turbine is connected to a simple model of a power system. Certain fault scenarios are specified and the turbine shall be able to sustain operation...
Simulation - modeling - experiment; Simulation - modelisation - experience
NONE
2004-07-01
After two workshops held in 2001 on the same topics, and in order to make a status of the advances in the domain of simulation and measurements, the main goals proposed for this workshop are: the presentation of the state-of-the-art of tools, methods and experiments in the domains of interest of the Gedepeon research group, the exchange of information about the possibilities of use of computer codes and facilities, about the understanding of physical and chemical phenomena, and about development and experiment needs. This document gathers 18 presentations (slides) among the 19 given at this workshop and dealing with: the deterministic and stochastic codes in reactor physics (Rimpault G.); MURE: an evolution code coupled with MCNP (Meplan O.); neutronic calculation of future reactors at EdF (Lecarpentier D.); advance status of the MCNP/TRIO-U neutronic/thermal-hydraulics coupling (Nuttin A.); the FLICA4/TRIPOLI4 thermal-hydraulics/neutronics coupling (Aniel S.); methods of disturbances and sensitivity analysis of nuclear data in reactor physics, application to VENUS-2 experimental reactor (Bidaud A.); modeling for the reliability improvement of an ADS accelerator (Biarotte J.L.); residual gas compensation of the space charge of intense beams (Ben Ismail A.); experimental determination and numerical modeling of phase equilibrium diagrams of interest in nuclear applications (Gachon J.C.); modeling of irradiation effects (Barbu A.); elastic limit and irradiation damage in Fe-Cr alloys: simulation and experiment (Pontikis V.); experimental measurements of spallation residues, comparison with Monte-Carlo simulation codes (Fallot M.); the spallation target-reactor coupling (Rimpault G.); tools and data (Grouiller J.P.); models in high energy transport codes: status and perspective (Leray S.); other ways of investigation for spallation (Audoin L.); neutrons and light particles production at intermediate energies (20-200 MeV) with iron, lead and uranium targets (Le Colley F
IVOA Recommendation: Simulation Data Model
Lemson, Gerard; Cervino, Miguel; Gheller, Claudio; Gray, Norman; LePetit, Franck; Louys, Mireille; Ooghe, Benjamin; Wagner, Rick; Wozniak, Herve
2014-01-01
In this document and the accompanying documents we describe a data model (Simulation Data Model) describing numerical computer simulations of astrophysical systems. The primary goal of this standard is to support discovery of simulations by describing those aspects of them that scientists might wish to query on, i.e. it is a model for meta-data describing simulations. This document does not propose a protocol for using this model. IVOA protocols are being developed and are supposed to use the model, either in its original form or in a form derived from the model proposed here, but more suited to the particular protocol. The SimDM has been developed in the IVOA Theory Interest Group with assistance of representatives of relevant working groups, in particular DM and Semantics.
Modeling and Simulation with INS.
Roberts, Stephen D.; And Others
INS, the Integrated Network Simulation language, puts simulation modeling into a network framework and automatically performs such programming activities as placing the problem into a next event structure, coding events, collecting statistics, monitoring status, and formatting reports. To do this, INS provides a set of symbols (nodes and branches)…
Point Processes Modeling of Time Series Exhibiting Power-Law Statistics
Kaulakys, B; Gontis, V
2010-01-01
We consider stochastic point processes generating time series exhibiting power laws of spectrum and distribution density (Phys. Rev. E 71, 051105 (2005)) and apply them for modeling the trading activity in the financial markets and for the frequencies of word occurrences in the language.
Simulation modeling of estuarine ecosystems
Johnson, R. W.
1980-01-01
A simulation model has been developed of Galveston Bay, Texas ecosystem. Secondary productivity measured by harvestable species (such as shrimp and fish) is evaluated in terms of man-related and controllable factors, such as quantity and quality of inlet fresh-water and pollutants. This simulation model used information from an existing physical parameters model as well as pertinent biological measurements obtained by conventional sampling techniques. Predicted results from the model compared favorably with those from comparable investigations. In addition, this paper will discuss remotely sensed and conventional measurements in the framework of prospective models that may be used to study estuarine processes and ecosystem productivity.
On the modelling of strength differential and anisotropy exhibited by titanium
Manopulo, Niko; Raemy, Christian; Hora, Pavel
2016-08-01
Modelling the response of titanium alloys under plastic deformation is challenging. In addition to strong anisotropy, these materials exhibit tension-compression asymmetry as well as anisotropic hardening even under monotonous loading conditions. The present contribution aims to propose a new modelling approach for titanium materials, by a homogeneous introduction of asymmetry into existing symmetric yield functions. Furthermore, anisotropic hardening effects are tracked describing the strain dependant yield surface evolution. The results are validated using the earing profile of deep drawn cups.
Modeling and Simulating Environmental Effects
Guest, Peter S.; Murphree, Tom; Frederickson, Paul A.; Guest, Arlene A.
2012-01-01
MOVES Research & Education Systems Seminar: Presentation; Session 4: Collaborative NWDC/NPS M&S Research; Moderator: Curtis Blais; Modeling and Simulating Environmental Effects; speakers: Peter Guest, Paul Frederickson & Tom Murphree Environmental Effects Group
TREAT Modeling and Simulation Strategy
DeHart, Mark David [Idaho National Lab. (INL), Idaho Falls, ID (United States)
2015-09-01
This report summarizes a four-phase process used to describe the strategy in developing modeling and simulation software for the Transient Reactor Test Facility. The four phases of this research and development task are identified as (1) full core transient calculations with feedback, (2) experiment modeling, (3) full core plus experiment simulation and (4) quality assurance. The document describes the four phases, the relationship between these research phases, and anticipated needs within each phase.
Stochastic modeling analysis and simulation
Nelson, Barry L
1995-01-01
A coherent introduction to the techniques for modeling dynamic stochastic systems, this volume also offers a guide to the mathematical, numerical, and simulation tools of systems analysis. Suitable for advanced undergraduates and graduate-level industrial engineers and management science majors, it proposes modeling systems in terms of their simulation, regardless of whether simulation is employed for analysis. Beginning with a view of the conditions that permit a mathematical-numerical analysis, the text explores Poisson and renewal processes, Markov chains in discrete and continuous time, se
Model reduction for circuit simulation
Hinze, Michael; Maten, E Jan W Ter
2011-01-01
Simulation based on mathematical models plays a major role in computer aided design of integrated circuits (ICs). Decreasing structure sizes, increasing packing densities and driving frequencies require the use of refined mathematical models, and to take into account secondary, parasitic effects. This leads to very high dimensional problems which nowadays require simulation times too large for the short time-to-market demands in industry. Modern Model Order Reduction (MOR) techniques present a way out of this dilemma in providing surrogate models which keep the main characteristics of the devi
A VRLA battery simulation model
Pascoe, P.E.; Anbuky, A.H. [Invensys Energy Systems NZ Limited, Christchurch (New Zealand)
2004-05-01
A valve regulated lead acid (VRLA) battery simulation model is an invaluable tool for the standby power system engineer. The obvious use for such a model is to allow the assessment of battery performance. This may involve determining the influence of cells suffering from state of health (SOH) degradation on the performance of the entire string, or the running of test scenarios to ascertain the most suitable battery size for the application. In addition, it enables the engineer to assess the performance of the overall power system. This includes, for example, running test scenarios to determine the benefits of various load shedding schemes. It also allows the assessment of other power system components, either for determining their requirements and/or vulnerabilities. Finally, a VRLA battery simulation model is vital as a stand alone tool for educational purposes. Despite the fundamentals of the VRLA battery having been established for over 100 years, its operating behaviour is often poorly understood. An accurate simulation model enables the engineer to gain a better understanding of VRLA battery behaviour. A system level multipurpose VRLA battery simulation model is presented. It allows an arbitrary battery (capacity, SOH, number of cells and number of strings) to be simulated under arbitrary operating conditions (discharge rate, ambient temperature, end voltage, charge rate and initial state of charge). The model accurately reflects the VRLA battery discharge and recharge behaviour. This includes the complex start of discharge region known as the coup de fouet. (author)
Modelling and Simulation: An Overview
M.J. McAleer (Michael); F. Chan (Felix); L. Oxley (Les)
2013-01-01
textabstractThe papers in this special issue of Mathematics and Computers in Simulation cover the following topics: improving judgmental adjustment of model-based forecasts, whether forecast updates are progressive, on a constrained mixture vector autoregressive model, whether all estimators are bor
General introduction to simulation models
Hisham Beshara Halasa, Tariq; Boklund, Anette
2012-01-01
Monte Carlo simulation can be defined as a representation of real life systems to gain insight into their functions and to investigate the effects of alternative conditions or actions on the modeled system. Models are a simplification of a system. Most often, it is best to use experiments and field...
Modelling, simulating and optimizing Boilers
Sørensen, Kim; Condra, Thomas Joseph; Houbak, Niels
2003-01-01
of the boiler has been developed and simulations carried out by means of the Matlab integration routines. The model is prepared as a dynamic model consisting of both ordinary differential equations and algebraic equations, together formulated as a Differential-Algebraic- Equation system. Being able to operate...
NIUShu-Li; PENGYu; JIANGGao-Ming; LIYong-Geng; GAOLei-Ming; LIUMei-Zhen; CUIHong-Xia; DINGLi
2004-01-01
To assess the ecophysiological responses and adaptive strategies to rainfall exhibited by different plant functional types, we compared gas exchange, leaf water potential (ψleaf) and PS photochemical efficiency (Fv/Fm) between Hedysarum fruticosum Pall. (shrub) and Salsola collina Y. L. Chang(herb) under a series of simulated rainfalls. The experiment was conducted in Hunshandak Sandy Land, North China. The values of net photosynthetic rate (Pn), transpiration rate (E), stomatal conductance (gs), Fv/Fm and ψleaf always elevated with the increasing amount of simulated rainfall. Whereas water useefficiency (WUE) maintained constant in H. fruticosum while always decreased in S.collina. Both speciesfully recovered their Pn and Fv/Fm 3d after rainfall, while gs and ψleaf recovered only within 2 d. However, the response patterns were obviously different. H.fruticosu promote its physiological traits within 5-15 mm rainfall but no further positive enhancement was noted when rainfall was larger than 15 mm. In S.collina, however, the enhancement continued with more water applied. We inferred that H.fruticosum and S.collina responded similarly to rainfall in time courses but differential to simulated precipitation change. S.collina was likely to be physiologically sensitive to instant increasing soil water, that can be regarded as a prodigal water use type; whilst H.fruticosum was a conservative water user.
Vehicle dynamics modeling and simulation
Schramm, Dieter; Bardini, Roberto
2014-01-01
The authors examine in detail the fundamentals and mathematical descriptions of the dynamics of automobiles. In this context different levels of complexity will be presented, starting with basic single-track models up to complex three-dimensional multi-body models. A particular focus is on the process of establishing mathematical models on the basis of real cars and the validation of simulation results. The methods presented are explained in detail by means of selected application scenarios.
Stochastic models: theory and simulation.
Field, Richard V., Jr.
2008-03-01
Many problems in applied science and engineering involve physical phenomena that behave randomly in time and/or space. Examples are diverse and include turbulent flow over an aircraft wing, Earth climatology, material microstructure, and the financial markets. Mathematical models for these random phenomena are referred to as stochastic processes and/or random fields, and Monte Carlo simulation is the only general-purpose tool for solving problems of this type. The use of Monte Carlo simulation requires methods and algorithms to generate samples of the appropriate stochastic model; these samples then become inputs and/or boundary conditions to established deterministic simulation codes. While numerous algorithms and tools currently exist to generate samples of simple random variables and vectors, no cohesive simulation tool yet exists for generating samples of stochastic processes and/or random fields. There are two objectives of this report. First, we provide some theoretical background on stochastic processes and random fields that can be used to model phenomena that are random in space and/or time. Second, we provide simple algorithms that can be used to generate independent samples of general stochastic models. The theory and simulation of random variables and vectors is also reviewed for completeness.
Computational Modeling of Simulation Tests.
1980-06-01
Mexico , March 1979. 14. Kinney, G. F.,.::. IeiN, .hoce 1h Ir, McMillan, p. 57, 1962. 15. Courant and Friedrichs, ,U: r. on moca an.: Jho...AD 79 275 NEW MEXICO UNIV ALBUGUERGUE ERIC H WANG CIVIL ENGINE-ETC F/6 18/3 COMPUTATIONAL MODELING OF SIMULATION TESTS.(U) JUN 80 6 LEIGH, W CHOWN, B...COMPUTATIONAL MODELING OF SIMULATION TESTS00 0G. Leigh W. Chown B. Harrison Eric H. Wang Civil Engineering Research Facility University of New Mexico
SIMULATION OF COLLECTIVE RISK MODEL
Viera Pacáková
2007-12-01
Full Text Available The article focuses on providing brief theoretical definitions of the basic terms and methods of modeling and simulations of insurance risks in non-life insurance by means of mathematical and statistical methods using statistical software. While risk assessment of insurance company in connection with its solvency is a rather complex and comprehensible problem, its solution starts with statistical modeling of number and amount of individual claims. Successful solution of these fundamental problems enables solving of curtail problems of insurance such as modeling and simulation of collective risk, premium an reinsurance premium calculation, estimation of probabiliy of ruin etc. The article also presents some essential ideas underlying Monte Carlo methods and their applications to modeling of insurance risk. Solving problem is to find the probability distribution of the collective risk in non-life insurance portfolio. Simulation of the compound distribution function of the aggregate claim amount can be carried out, if the distibution functions of the claim number process and the claim size are assumed given. The Monte Carlo simulation is suitable method to confirm the results of other methods and for treatments of catastrophic claims, when small collectives are studied. Analysis of insurance risks using risk theory is important part of the project Solvency II. Risk theory is analysis of stochastic features of non-life insurance process. The field of application of risk theory has grown rapidly. There is a need to develop the theory into form suitable for practical purposes and demostrate their application. Modern computer simulation techniques open up a wide field of practical applications for risk theory concepts, without requiring the restricive assumptions and sophisticated mathematics. This article presents some comparisons of the traditional actuarial methods and of simulation methods of the collective risk model.
A Simulation Model Articulation of the REA Ontology
Laurier, Wim; Poels, Geert
This paper demonstrates how the REA enterprise ontology can be used to construct simulation models for business processes, value chains and collaboration spaces in supply chains. These models support various high-level and operational management simulation applications, e.g. the analysis of enterprise sustainability and day-to-day planning. First, the basic constructs of the REA ontology and the ExSpect modelling language for simulation are introduced. Second, collaboration space, value chain and business process models and their conceptual dependencies are shown, using the ExSpect language. Third, an exhibit demonstrates the use of value chain models in predicting the financial performance of an enterprise.
MODELLING, SIMULATING AND OPTIMIZING BOILERS
Sørensen, K.; Condra, T.; Houbak, Niels
2003-01-01
This paper describes the modelling, simulating and optimizing including experimental verification as being carried out as part of a Ph.D. project being written resp. supervised by the authors. The work covers dynamic performance of both water-tube boilers and fire tube boilers. A detailed dynamic...... model of the boiler has been developed and simulations carried out by means of the Matlab integration routines. The model is prepared as a dynamic model consisting of both ordinary differential equations and algebraic equations, together formulated as a Differential-Algebraic-Equation system. Being able...... to operate a boiler plant dynamically means that the boiler designs must be able to absorb any fluctuations in water level and temperature gradients resulting from the pressure change in the boiler. On the one hand a large water-/steam space may be required, i.e. to build the boiler as big as possible. Due...
Intelligent Mobility Modeling and Simulation
2015-03-04
cog.cs.drexel.edu/act-r/index.html) •Models sensory / motor performance of human driver or teleoperator 27UNCLASSIFIED: Distribution Statement A. Approved for...U.S. ARMY TANK AUTOMOTIVE RESEARCH, DEVELOPMENT AND ENGINEERING CENTER Intelligent Mobility Modeling and Simulation 1 Dr. P. Jayakumar, S. Arepally...Prescribed by ANSI Std Z39-18 Contents 1. Mobility - Autonomy - Latency Relationship 2. Machine - Human Partnership 3. Development of Shared Control
Design and creating model and interactive presentation of GEM for Microcosm Exhibition
Lakdee, Natthaphop
2017-01-01
GEM or Gas Electron Multiplier is the newer and easier way to amplify electron signal than conventional CSS. It was first created by Fabio Sauli at CERN in 1997 and was developed to get better efficiency over time. Right now, it was brought to use in many detector stations at CERN. To make GEM more publicly known, one of the ways is show in Microcosm Exhibition which is always visited by people from around the world everyday, so my main project as summer student is to design and create the model and interactive presentation which make GEM interesting and easy to understand by ordinary people.
Droplet Lamp Design exhibition
Unver, Ertu; Dean, Lionel Theodore
2011-01-01
This paper describes experiments in the use of digital fluid simulation techniques within a\\ud product design context. It discusses the adoption and adaptation of virtual modelling tools in\\ud 3D creative practice. This work is exhibited at EuroMold, the world-wide fair in Germany for\\ud mold making, tooling, design and application development with around 60.000 visitors and lasts\\ud 4 days. The fair brings together professionals from design, prototyping and manufacturing.
MODELLING, SIMULATING AND OPTIMIZING BOILERS
Sørensen, Kim; Condra, Thomas Joseph; Houbak, Niels
2004-01-01
on the boiler) have been dened. Furthermore a number of constraints related to: minimum and maximum boiler load gradient, minimum boiler size, Shrinking and Swelling and Steam Space Load have been dened. For dening the constraints related to the required boiler volume a dynamic model for simulating the boiler...... performance has been developed. Outputs from the simulations are shrinking and swelling of water level in the drum during for example a start-up of the boiler, these gures combined with the requirements with respect to allowable water level uctuations in the drum denes the requirements with respect to drum...... size. The model has been formulated with a specied building-up of the pressure during the start-up of the plant, i.e. the steam production during start-up of the boiler is output from the model. The steam outputs together with requirements with respect to steam space load have been utilized to dene...
Modeling and Simulation of Nanoindentation
Huang, Sixie; Zhou, Caizhi
2017-08-01
Nanoindentation is a hardness test method applied to small volumes of material which can provide some unique effects and spark many related research activities. To fully understand the phenomena observed during nanoindentation tests, modeling and simulation methods have been developed to predict the mechanical response of materials during nanoindentation. However, challenges remain with those computational approaches, because of their length scale, predictive capability, and accuracy. This article reviews recent progress and challenges for modeling and simulation of nanoindentation, including an overview of molecular dynamics, the quasicontinuum method, discrete dislocation dynamics, and the crystal plasticity finite element method, and discusses how to integrate multiscale modeling approaches seamlessly with experimental studies to understand the length-scale effects and microstructure evolution during nanoindentation tests, creating a unique opportunity to establish new calibration procedures for the nanoindentation technique.
Multiscale Stochastic Simulation and Modeling
James Glimm; Xiaolin Li
2006-01-10
Acceleration driven instabilities of fluid mixing layers include the classical cases of Rayleigh-Taylor instability, driven by a steady acceleration and Richtmyer-Meshkov instability, driven by an impulsive acceleration. Our program starts with high resolution methods of numerical simulation of two (or more) distinct fluids, continues with analytic analysis of these solutions, and the derivation of averaged equations. A striking achievement has been the systematic agreement we obtained between simulation and experiment by using a high resolution numerical method and improved physical modeling, with surface tension. Our study is accompanies by analysis using stochastic modeling and averaged equations for the multiphase problem. We have quantified the error and uncertainty using statistical modeling methods.
Assessment of Molecular Modeling & Simulation
None
2002-01-03
This report reviews the development and applications of molecular and materials modeling in Europe and Japan in comparison to those in the United States. Topics covered include computational quantum chemistry, molecular simulations by molecular dynamics and Monte Carlo methods, mesoscale modeling of material domains, molecular-structure/macroscale property correlations like QSARs and QSPRs, and related information technologies like informatics and special-purpose molecular-modeling computers. The panel's findings include the following: The United States leads this field in many scientific areas. However, Canada has particular strengths in DFT methods and homogeneous catalysis; Europe in heterogeneous catalysis, mesoscale, and materials modeling; and Japan in materials modeling and special-purpose computing. Major government-industry initiatives are underway in Europe and Japan, notably in multi-scale materials modeling and in development of chemistry-capable ab-initio molecular dynamics codes.
Animal models for simulating weightlessness
Morey-Holton, E.; Wronski, T. J.
1982-01-01
NASA has developed a rat model to simulate on earth some aspects of the weightlessness alterations experienced in space, i.e., unloading and fluid shifts. Comparison of data collected from space flight and from the head-down rat suspension model suggests that this model system reproduces many of the physiological alterations induced by space flight. Data from various versions of the rat model are virtually identical for the same parameters; thus, modifications of the model for acute, chronic, or metabolic studies do not alter the results as long as the critical components of the model are maintained, i.e., a cephalad shift of fluids and/or unloading of the rear limbs.
William eLennon
2014-12-01
Full Text Available While the anatomy of the cerebellar microcircuit is well studied, how it implements cerebellar function is not understood. A number of models have been proposed to describe this mechanism but few emphasize the role of the vast network Purkinje cells (PKJs form with the molecular layer interneurons (MLIs – the stellate and basket cells. We propose a model of the MLI-PKJ network composed of simple spiking neurons incorporating the major anatomical and physiological features. In computer simulations, the model reproduces the irregular firing patterns observed in PKJs and MLIs in vitro and a shift toward faster, more regular firing patterns when inhibitory synaptic currents are blocked. In the model, the time between PKJ spikes is shown to be proportional to the amount of feedforward inhibition from an MLI on average. The two key elements of the model are: (1 spontaneously active PKJs and MLIs due to an endogenous depolarizing current, and (2 adherence to known anatomical connectivity along a parasagittal strip of cerebellar cortex. We propose this model to extend previous spiking network models of the cerebellum and for further computational investigation into the role of irregular firing and MLIs in cerebellar learning and function.
Simulation Tool for Inventory Models: SIMIN
Pratiksha Saxen; Tulsi Kushwaha
2014-01-01
In this paper, an integrated simulation optimization model for the inventory system is developed. An effective algorithm is developed to evaluate and analyze the back-end stored simulation results. This paper proposes simulation tool SIMIN (Inventory Simulation) to simulate inventory models. SIMIN is a tool which simulates and compares the results of different inventory models. To overcome various practical restrictive assumptions, SIMIN provides values for a number of performance measurement...
Jerry S Chen
2014-06-01
Full Text Available Notch-Delta signaling is a fundamental cell-cell communication mechanism that governs the differentiation of many cell types. Most existing mathematical models of Notch-Delta signaling are based on a feedback loop between Notch and Delta leading to lateral inhibition of neighboring cells. These models result in a checkerboard spatial pattern whereby adjacent cells express opposing levels of Notch and Delta, leading to alternate cell fates. However, a growing body of biological evidence suggests that Notch-Delta signaling produces other patterns that are not checkerboard, and therefore a new model is needed. Here, we present an expanded Notch-Delta model that builds upon previous models, adding a local Notch activity gradient, which affects long-range patterning, and the activity of a regulatory microRNA. This model is motivated by our experiments in the ascidian Ciona intestinalis showing that the peripheral sensory neurons, whose specification is in part regulated by the coordinate activity of Notch-Delta signaling and the microRNA miR-124, exhibit a sparse spatial pattern whereby consecutive neurons may be spaced over a dozen cells apart. We perform rigorous stability and bifurcation analyses, and demonstrate that our model is able to accurately explain and reproduce the neuronal pattern in Ciona. Using Monte Carlo simulations of our model along with miR-124 transgene over-expression assays, we demonstrate that the activity of miR-124 can be incorporated into the Notch decay rate parameter of our model. Finally, we motivate the general applicability of our model to Notch-Delta signaling in other animals by providing evidence that microRNAs regulate Notch-Delta signaling in analogous cell types in other organisms, and by discussing evidence in other organisms of sparse spatial patterns in tissues where Notch-Delta signaling is active.
A Bounding Surface Plasticity Model for Intact Rock Exhibiting Size-Dependent Behaviour
Masoumi, Hossein; Douglas, Kurt J.; Russell, Adrian R.
2016-01-01
A new constitutive model for intact rock is presented recognising that rock strength, stiffness and stress-strain behaviour are affected by the size of the rock being subjected to loading. The model is formulated using bounding surface plasticity theory. It is validated against a new and extensive set of unconfined compression and triaxial compression test results for Gosford sandstone. The samples tested had diameters ranging from 19 to 145 mm and length-to-diameter ratios of 2. The model captures the continuous nonlinear stress-strain behaviour from initial loading, through peak strength to large shear strains, including transition from brittle to ductile behaviour. The size dependency was accounted for through a unified size effect law applied to the unconfined compressive strength—a key model input parameter. The unconfined compressive strength increases with sample size before peaking and then decreasing with further increasing sample size. Inside the constitutive model two hardening laws act simultaneously, each driven by plastic shear strains. The elasticity is stress level dependent. Simple linear loading and bounding surfaces are adopted, defined using the Mohr-Coulomb criterion, along with a non-associated flow rule. The model simulates well the stress-strain behaviour of Gosford sandstone at confining pressures ranging from 0 to 30 MPa for the variety of sample sizes considered.
Standard for Models and Simulations
Steele, Martin J.
2016-01-01
This NASA Technical Standard establishes uniform practices in modeling and simulation to ensure essential requirements are applied to the design, development, and use of models and simulations (MS), while ensuring acceptance criteria are defined by the program project and approved by the responsible Technical Authority. It also provides an approved set of requirements, recommendations, and criteria with which MS may be developed, accepted, and used in support of NASA activities. As the MS disciplines employed and application areas involved are broad, the common aspects of MS across all NASA activities are addressed. The discipline-specific details of a given MS should be obtained from relevant recommended practices. The primary purpose is to reduce the risks associated with MS-influenced decisions by ensuring the complete communication of the credibility of MS results.
WiBro Mobility Simulation Model
Junaid Qayyum
2011-09-01
Full Text Available WiBro, or Wireless Broadband, is the newest variety of mobile wireless broadband access. WiBro technology is being developed by the Korean Telecoms industry. It is based on the IEEE 802.16e (Mobile WiMax international standard. Korean based fixed-line operators KT, SK Telecom were the first to get the licenses by the South Korean government to provide WiBro Commercially. Samsung had a demonstration on WiBro Mobile Phones and Systems at the "APEC IT Exhibition 2006". WiBro is comprised of two phases namely WiBro Phase I and WiBro Phase II. Samsung Electronics has been extensively contributing to Koreas WiBro (Wireless Broadband initiative as well as the IEEE 802.16 standards. The WiBro is a specific subset of the 802.16 standards, specially focusing on supporting full mobility of wireless access systems with OFDMA PHY interface. In this work, we have developed a simulation model of the WiBro system consisting of a set of Base Stations and Mobile Subscriber Stations by using the OPNET Modeler. The simulation model has been utilized to evaluate effective MAC layer throughput, resource usage efficiency, QoS class differentiation, and system capacity and performance under various simulation scenarios.
Ruith, Michael Rudolf
Vortex breakdown of nominally axisymmetric, swirling incompressible jets and wakes issuing into a semi-infinite domain is studied by means of direct numerical simulations, as well as local and global linear stability analyses. From the point of view of specifying conditions at the open boundaries, this class of flows is particularly challenging due to its ability to support traveling waves. Several boundary conditions, ranging from free-slip and various homogeneous Neumann conditions to radiation conditions, are implemented in a staggered grid, finite difference algorithm that solves the unsteady Navier-Stokes equations in cylindrical coordinates by means of a fractional step method. Their advantages and shortcomings are evaluated in detail, and the question of the proper implementation of intermediate step boundary conditions is addressed. The data obtained from a large variety of test simulations points to the radiation condition as the most suitable lateral and outflow boundary condition for both high and low entrainment jets and wakes. A two-parameterc low entrainment velocity profile for which the steady, axisymmetric breakdown is well studied is selected for further investigation. Hence, issues regarding the role of three-dimensionality and unsteadiness with respect to the existence, mode selection, and internal structure of vortex breakdown can be addressed in terms of the two governing parameters and the Reynolds number. Low Reynolds numbers are found to yield flow fields lacking breakdown bubbles or helical breakdown modes even for high swirl. In contrast, highly swirling flows at large Reynolds numbers exhibit bubble, helical or double helical breakdown modes, where the axisymmetric mode is promoted by a jet-like axial velocity profile, while a wake-like profile renders the flow helically unstable and ultimately yields non-axisymmetric breakdown modes. It is shown that a transition from super- to subcritical flow, accurately predicts the parameter
Model for Simulation Atmospheric Turbulence
Lundtang Petersen, Erik
1976-01-01
A method that produces realistic simulations of atmospheric turbulence is developed and analyzed. The procedure makes use of a generalized spectral analysis, often called a proper orthogonal decomposition or the Karhunen-Loève expansion. A set of criteria, emphasizing a realistic appearance, a co....... The method is unique in modeling the three velocity components simultaneously, and it is found that important cross-statistical features are reasonably well-behaved. It is concluded that the model provides a practical, operational simulator of atmospheric turbulence.......A method that produces realistic simulations of atmospheric turbulence is developed and analyzed. The procedure makes use of a generalized spectral analysis, often called a proper orthogonal decomposition or the Karhunen-Loève expansion. A set of criteria, emphasizing a realistic appearance......, a correct spectral shape, and non-Gaussian statistics, is selected in order to evaluate the model turbulence. An actual turbulence record is analyzed in detail providing both a standard for comparison and input statistics for the generalized spectral analysis, which in turn produces a set of orthonormal...
Modeling Information for Three-Dimensional Space: Lessons Learned from Museum Exhibit Design.
Carliner, Saul
2001-01-01
Reports results of an observational study of museum exhibit design. Suggests eight communication practices from successful museum exhibit design that could be transferred to information design for the Web. (SR)
Magnetostriction simulation using anisotropic vector Preisach-type models
Adly, A.A. [Cairo Univ., Giza (Egypt). Electric Power and Machines Dept.; Mayergoyz, I.D. [Univ. of Maryland, College Park, MD (United States). Electrical Engineering Dept.
1996-09-01
Magnetic materials exhibiting gigantic magnetostriction, especially Terfenol, are currently being widely used in fine positioning and active vibration damping devices. By involving accurate magnetostriction models during design stages, precision of such devices may be significantly enhanced. In this paper a straight-forward approach that employs anisotropic vector Preisach-type hysteresis models in simulating field-stress effects on magnetic materials is presented. Formulation of the proposed model is given and its identification problem is solved. The presented approach has been numerically implemented and numerous digital computer simulations have been performed for Terfenol material. Sample simulation results as well as comparisons with experimentally observed magnetostriction curves are reported in the paper.
Sønderholm, Majken; Kragh, Kasper Nørskov; Koren, Klaus; Jakobsen, Tim Holm; Darch, Sophie E; Alhede, Maria; Jensen, Peter Østrup; Whiteley, Marvin; Kühl, Michael; Bjarnsholt, Thomas
2017-05-01
Alginate beads represent a simple and highly reproducible in vitro model system for diffusion-limited bacterial growth. In this study, alginate beads were inoculated with Pseudomonas aeruginosa and followed for up to 72 h. Confocal microscopy revealed that P. aeruginosa formed dense clusters similar in size to in vivo aggregates observed ex vivo in cystic fibrosis lungs and chronic wounds. Bacterial aggregates primarily grew in the bead periphery and decreased in size and abundance toward the center of the bead. Microsensor measurements showed that the O2 concentration decreased rapidly and reached anoxia ∼100 μm below the alginate bead surface. This gradient was relieved in beads supplemented with NO3(-) as an alternative electron acceptor allowing for deeper growth into the beads. A comparison of gene expression profiles between planktonic and alginate-encapsulated P. aeruginosa confirmed that the bacteria experienced hypoxic and anoxic growth conditions. Furthermore, alginate-encapsulated P. aeruginosa exhibited a lower respiration rate than the planktonic counterpart and showed a high tolerance toward antibiotics. The inoculation and growth of P. aeruginosa in alginate beads represent a simple and flexible in vivo-like biofilm model system, wherein bacterial growth exhibits central features of in vivo biofilms. This was observed by the formation of small cell aggregates in a secondary matrix with O2-limited growth, which was alleviated by the addition of NO3(-) as an alternative electron acceptor, and by reduced respiration rates, as well as an enhanced tolerance to antibiotic treatment.IMPORTANCEPseudomonas aeruginosa has been studied intensively for decades due to its involvement in chronic infections, such as cystic fibrosis and chronic wounds, where it forms biofilms. Much research has been dedicated to biofilm formation on surfaces; however, in chronic infections, most biofilms form small aggregates of cells not attached to a surface, but embedded in
Advances in Intelligent Modelling and Simulation Simulation Tools and Applications
Oplatková, Zuzana; Carvalho, Marco; Kisiel-Dorohinicki, Marek
2012-01-01
The human capacity to abstract complex systems and phenomena into simplified models has played a critical role in the rapid evolution of our modern industrial processes and scientific research. As a science and an art, Modelling and Simulation have been one of the core enablers of this remarkable human trace, and have become a topic of great importance for researchers and practitioners. This book was created to compile some of the most recent concepts, advances, challenges and ideas associated with Intelligent Modelling and Simulation frameworks, tools and applications. The first chapter discusses the important aspects of a human interaction and the correct interpretation of results during simulations. The second chapter gets to the heart of the analysis of entrepreneurship by means of agent-based modelling and simulations. The following three chapters bring together the central theme of simulation frameworks, first describing an agent-based simulation framework, then a simulator for electrical machines, and...
Verifying and Validating Simulation Models
Hemez, Francois M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
2015-02-23
This presentation is a high-level discussion of the Verification and Validation (V&V) of computational models. Definitions of V&V are given to emphasize that “validation” is never performed in a vacuum; it accounts, instead, for the current state-of-knowledge in the discipline considered. In particular comparisons between physical measurements and numerical predictions should account for their respective sources of uncertainty. The differences between error (bias), aleatoric uncertainty (randomness) and epistemic uncertainty (ignorance, lack-of- knowledge) are briefly discussed. Four types of uncertainty in physics and engineering are discussed: 1) experimental variability, 2) variability and randomness, 3) numerical uncertainty and 4) model-form uncertainty. Statistical sampling methods are available to propagate, and analyze, variability and randomness. Numerical uncertainty originates from the truncation error introduced by the discretization of partial differential equations in time and space. Model-form uncertainty is introduced by assumptions often formulated to render a complex problem more tractable and amenable to modeling and simulation. The discussion concludes with high-level guidance to assess the “credibility” of numerical simulations, which stems from the level of rigor with which these various sources of uncertainty are assessed and quantified.
MODELLING, SIMULATING AND OPTIMIZING BOILERS
Sørensen, Kim; Condra, Thomas Joseph; Houbak, Niels
2004-01-01
on the boiler) have been dened. Furthermore a number of constraints related to: minimum and maximum boiler load gradient, minimum boiler size, Shrinking and Swelling and Steam Space Load have been dened. For dening the constraints related to the required boiler volume a dynamic model for simulating the boiler...... size. The model has been formulated with a specied building-up of the pressure during the start-up of the plant, i.e. the steam production during start-up of the boiler is output from the model. The steam outputs together with requirements with respect to steam space load have been utilized to dene...... of the boiler is (with an acceptable accuracy) proportional with the volume of the boiler. For the dynamic operation capability a cost function penalizing limited dynamic operation capability and vise-versa has been dened. The main idea is that it by mean of the parameters in this function is possible to t its...
Simulated annealing model of acupuncture
Shang, Charles; Szu, Harold
2015-05-01
The growth control singularity model suggests that acupuncture points (acupoints) originate from organizers in embryogenesis. Organizers are singular points in growth control. Acupuncture can cause perturbation of a system with effects similar to simulated annealing. In clinical trial, the goal of a treatment is to relieve certain disorder which corresponds to reaching certain local optimum in simulated annealing. The self-organizing effect of the system is limited and related to the person's general health and age. Perturbation at acupoints can lead a stronger local excitation (analogous to higher annealing temperature) compared to perturbation at non-singular points (placebo control points). Such difference diminishes as the number of perturbed points increases due to the wider distribution of the limited self-organizing activity. This model explains the following facts from systematic reviews of acupuncture trials: 1. Properly chosen single acupoint treatment for certain disorder can lead to highly repeatable efficacy above placebo 2. When multiple acupoints are used, the result can be highly repeatable if the patients are relatively healthy and young but are usually mixed if the patients are old, frail and have multiple disorders at the same time as the number of local optima or comorbidities increases. 3. As number of acupoints used increases, the efficacy difference between sham and real acupuncture often diminishes. It predicted that the efficacy of acupuncture is negatively correlated to the disease chronicity, severity and patient's age. This is the first biological - physical model of acupuncture which can predict and guide clinical acupuncture research.
Towards a model for research-based exhibition development using design-based research as a framework
Zachariassen, Maria; Magnussen, Rikke; Thiel Sandholdt, Cathrina
2016-01-01
practices. A research-based approach can expand understanding of exhibitions as a media, encouraging a more systematised, theory-based and documented practice. This premise forms the basis for creating a model for collaboration between research and exhibition development in a science centre context......This paper argues that a higher level of research activity is necessary at all levels in the creation of science centre exhibitions. Science centres focus greatly on their role as an informal learning space but rarely integrate learning theories or develop documented knowledge in their exhibition...... that facilitates an iterative research-based development process and that emphasises focusing on learning elements. We present a new model for developing research-based exhibitions and provide an accompanying analysis based on PULSE, a four-year project involving the development of a health promotion exhibition...
Uterine Contraction Modeling and Simulation
Liu, Miao; Belfore, Lee A.; Shen, Yuzhong; Scerbo, Mark W.
2010-01-01
Building a training system for medical personnel to properly interpret fetal heart rate tracing requires developing accurate models that can relate various signal patterns to certain pathologies. In addition to modeling the fetal heart rate signal itself, the change of uterine pressure that bears strong relation to fetal heart rate and provides indications of maternal and fetal status should also be considered. In this work, we have developed a group of parametric models to simulate uterine contractions during labor and delivery. Through analysis of real patient records, we propose to model uterine contraction signals by three major components: regular contractions, impulsive noise caused by fetal movements, and low amplitude noise invoked by maternal breathing and measuring apparatus. The regular contractions are modeled by an asymmetric generalized Gaussian function and least squares estimation is used to compute the parameter values of the asymmetric generalized Gaussian function based on uterine contractions of real patients. Regular contractions are detected based on thresholding and derivative analysis of uterine contractions. Impulsive noise caused by fetal movements and low amplitude noise by maternal breathing and measuring apparatus are modeled by rational polynomial functions and Perlin noise, respectively. Experiment results show the synthesized uterine contractions can mimic the real uterine contractions realistically, demonstrating the effectiveness of the proposed algorithm.
Applications of Joint Tactical Simulation Modeling
1997-12-01
NAVAL POSTGRADUATE SCHOOL Monterey, California THESIS APPLICATIONS OF JOINT TACTICAL SIMULATION MODELING by Steve VanLandingham December 1997...SUBTITLE APPLICATIONS OF JOINT TACTICAL SIMULATION MODELING 5. FUNDING NUMBERS 6. AUTHOR(S) VanLandingham, Steve 7. PERFORMING ORGANIZATION NAME(S...release; distribution is unlimited. APPLICATIONS OF JOINT TACTICAL SIMULATION MODELING Steve VanLandingham Lieutenant, United States Navy B.S
Benchmark simulation models, quo vadis?
Jeppsson, U.; Alex, J; Batstone, D. J.
2013-01-01
As the work of the IWA Task Group on Benchmarking of Control Strategies for wastewater treatment plants (WWTPs) is coming to an end, it is essential to disseminate the knowledge gained. For this reason, all authors of the IWA Scientific and Technical Report on benchmarking have come together to p...... already being done within the context of the benchmarking simulation models (BSMs) or applicable work in the wider literature. Of key importance is increasing capability, usability and transparency of the BSM package while avoiding unnecessary complexity. © IWA Publishing 2013....... and spatial extension, process modifications within the WWTP, the realism of models, control strategy extensions and the potential for new evaluation tools within the existing benchmark system. We find that there are major opportunities for application within all of these areas, either from existing work...
SWEEPOP a simulation model for Target Simulation Mode minesweeping
Keus, H.E.; Beckers, A.L.D.; Cleophas, P.L.H.
2005-01-01
SWEEPOP is a flexible model that simulates the physical interaction between objects in a maritime underwater environment. The model was built to analyse the deployment and the performance of a Target Simulation Mode (TSM) minesweeping system for the Royal Netherlands Navy (RNLN) and to support its p
Techniques and Simulation Models in Risk Management
Mirela GHEORGHE
2012-01-01
In the present paper, the scientific approach of the research starts from the theoretical framework of the simulation concept and then continues in the setting of the practical reality, thus providing simulation models for a broad range of inherent risks specific to any organization and simulation of those models, using the informatics instrument @Risk (Palisade). The reason behind this research lies in the need for simulation models that will allow the person in charge with decision taking i...
Modelling, simulation and inference for multivariate time series of counts
Veraart, Almut E. D.
2016-01-01
This article presents a new continuous-time modelling framework for multivariate time series of counts which have an infinitely divisible marginal distribution. The model is based on a mixed moving average process driven by L\\'{e}vy noise - called a trawl process - where the serial correlation and the cross-sectional dependence are modelled independently of each other. Such processes can exhibit short or long memory. We derive a stochastic simulation algorithm and a statistical inference meth...
Bridging experiments, models and simulations
Carusi, Annamaria; Burrage, Kevin; Rodríguez, Blanca
2012-01-01
Computational models in physiology often integrate functional and structural information from a large range of spatiotemporal scales from the ionic to the whole organ level. Their sophistication raises both expectations and skepticism concerning how computational methods can improve our understan...... that contributes to defining the specific aspects of cardiac electrophysiology the MSE system targets, rather than being only an external test, and that this is driven by advances in experimental and computational methods and the combination of both....... of biovariability; 2) testing and developing robust techniques and tools as a prerequisite to conducting physiological investigations; 3) defining and adopting standards to facilitate the interoperability of experiments, models, and simulations; 4) and understanding physiological validation as an iterative process...... understanding of living organisms and also how they can reduce, replace, and refine animal experiments. A fundamental requirement to fulfill these expectations and achieve the full potential of computational physiology is a clear understanding of what models represent and how they can be validated. The present...
Distributed simulation a model driven engineering approach
Topçu, Okan; Oğuztüzün, Halit; Yilmaz, Levent
2016-01-01
Backed by substantive case studies, the novel approach to software engineering for distributed simulation outlined in this text demonstrates the potent synergies between model-driven techniques, simulation, intelligent agents, and computer systems development.
Benchmark simulation models, quo vadis?
Jeppsson, U; Alex, J; Batstone, D J; Benedetti, L; Comas, J; Copp, J B; Corominas, L; Flores-Alsina, X; Gernaey, K V; Nopens, I; Pons, M-N; Rodríguez-Roda, I; Rosen, C; Steyer, J-P; Vanrolleghem, P A; Volcke, E I P; Vrecko, D
2013-01-01
As the work of the IWA Task Group on Benchmarking of Control Strategies for wastewater treatment plants (WWTPs) is coming to an end, it is essential to disseminate the knowledge gained. For this reason, all authors of the IWA Scientific and Technical Report on benchmarking have come together to provide their insights, highlighting areas where knowledge may still be deficient and where new opportunities are emerging, and to propose potential avenues for future development and application of the general benchmarking framework and its associated tools. The paper focuses on the topics of temporal and spatial extension, process modifications within the WWTP, the realism of models, control strategy extensions and the potential for new evaluation tools within the existing benchmark system. We find that there are major opportunities for application within all of these areas, either from existing work already being done within the context of the benchmarking simulation models (BSMs) or applicable work in the wider literature. Of key importance is increasing capability, usability and transparency of the BSM package while avoiding unnecessary complexity.
Andreassen, Rikke
From 1870s to 1910s, more than 50 exhibitions of so-called exotic people took place in Denmark. Here large numbers of people of Asian and African origin were exhibited for the entertainment and ‘education’ of a mass audience. Several of these exhibitions took place in Copenhagen Zoo. Here different...... light on the staging of exhibitions, the daily life of the exhibitees, the wider connections between shows across Europe and the thinking of the time on matters of race, science, gender and sexuality. A window onto contemporary racial understandings, the book presents interviews with the descendants...... of displayed people, connecting the attitudes and science of the past with both our (continued) modern fascination with ‘the exotic’, and contemporary language and popular culture. As such, it will be of interest to scholars of sociology, anthropology and history working in the areas of gender and sexuality...
Structured building model reduction toward parallel simulation
Dobbs, Justin R. [Cornell University; Hencey, Brondon M. [Cornell University
2013-08-26
Building energy model reduction exchanges accuracy for improved simulation speed by reducing the number of dynamical equations. Parallel computing aims to improve simulation times without loss of accuracy but is poorly utilized by contemporary simulators and is inherently limited by inter-processor communication. This paper bridges these disparate techniques to implement efficient parallel building thermal simulation. We begin with a survey of three structured reduction approaches that compares their performance to a leading unstructured method. We then use structured model reduction to find thermal clusters in the building energy model and allocate processing resources. Experimental results demonstrate faster simulation and low error without any interprocessor communication.
Simulation and Modeling Methodologies, Technologies and Applications
Filipe, Joaquim; Kacprzyk, Janusz; Pina, Nuno
2014-01-01
This book includes extended and revised versions of a set of selected papers from the 2012 International Conference on Simulation and Modeling Methodologies, Technologies and Applications (SIMULTECH 2012) which was sponsored by the Institute for Systems and Technologies of Information, Control and Communication (INSTICC) and held in Rome, Italy. SIMULTECH 2012 was technically co-sponsored by the Society for Modeling & Simulation International (SCS), GDR I3, Lionphant Simulation, Simulation Team and IFIP and held in cooperation with AIS Special Interest Group of Modeling and Simulation (AIS SIGMAS) and the Movimento Italiano Modellazione e Simulazione (MIMOS).
An introduction to enterprise modeling and simulation
Ostic, J.K.; Cannon, C.E. [Los Alamos National Lab., NM (United States). Technology Modeling and Analysis Group
1996-09-01
As part of an ongoing effort to continuously improve productivity, quality, and efficiency of both industry and Department of Energy enterprises, Los Alamos National Laboratory is investigating various manufacturing and business enterprise simulation methods. A number of enterprise simulation software models are being developed to enable engineering analysis of enterprise activities. In this document the authors define the scope of enterprise modeling and simulation efforts, and review recent work in enterprise simulation at Los Alamos National Laboratory as well as at other industrial, academic, and research institutions. References of enterprise modeling and simulation methods and a glossary of enterprise-related terms are provided.
A physiological production model for cacao : results of model simulations
Zuidema, P.A.; Leffelaar, P.A.
2002-01-01
CASE2 is a physiological model for cocoa (Theobroma cacao L.) growth and yield. This report introduces the CAcao Simulation Engine for water-limited production in a non-technical way and presents simulation results obtained with the model.
A physiological production model for cacao : results of model simulations
Zuidema, P.A.; Leffelaar, P.A.
2002-01-01
CASE2 is a physiological model for cocoa (Theobroma cacao L.) growth and yield. This report introduces the CAcao Simulation Engine for water-limited production in a non-technical way and presents simulation results obtained with the model.
SIRS Dynamics on Random Networks: Simulations and Analytical Models
Rozhnova, Ganna; Nunes, Ana
The standard pair approximation equations (PA) for the Susceptible-Infective-Recovered-Susceptible (SIRS) model of infection spread on a network of homogeneous degree k predict a thin phase of sustained oscillations for parameter values that correspond to diseases that confer long lasting immunity. Here we present a study of the dependence of this oscillatory phase on the parameter k and of its relevance to understand the behaviour of simulations on networks. For k = 4, we compare the phase diagram of the PA model with the results of simulations on regular random graphs (RRG) of the same degree. We show that for parameter values in the oscillatory phase, and even for large system sizes, the simulations either die out or exhibit damped oscillations, depending on the initial conditions. This failure of the standard PA model to capture the qualitative behaviour of the simulations on large RRGs is currently being investigated.
Simulation modeling and analysis with Arena
Altiok, Tayfur
2007-01-01
Simulation Modeling and Analysis with Arena is a highly readable textbook which treats the essentials of the Monte Carlo discrete-event simulation methodology, and does so in the context of a popular Arena simulation environment. It treats simulation modeling as an in-vitro laboratory that facilitates the understanding of complex systems and experimentation with what-if scenarios in order to estimate their performance metrics. The book contains chapters on the simulation modeling methodology and the underpinnings of discrete-event systems, as well as the relevant underlying probability, statistics, stochastic processes, input analysis, model validation and output analysis. All simulation-related concepts are illustrated in numerous Arena examples, encompassing production lines, manufacturing and inventory systems, transportation systems, and computer information systems in networked settings.· Introduces the concept of discrete event Monte Carlo simulation, the most commonly used methodology for modeli...
Nonsmooth Modeling and Simulation for Switched Circuits
Acary, Vincent; Brogliato, Bernard
2011-01-01
"Nonsmooth Modeling and Simulation for Switched Circuits" concerns the modeling and the numerical simulation of switched circuits with the nonsmooth dynamical systems (NSDS) approach, using piecewise-linear and multivalued models of electronic devices like diodes, transistors, switches. Numerous examples (ranging from introductory academic circuits to various types of power converters) are analyzed and many simulation results obtained with the INRIA open-source SICONOS software package are presented. Comparisons with SPICE and hybrid methods demonstrate the power of the NSDS approach
Juno model rheometry and simulation
Sampl, Manfred; Macher, Wolfgang; Oswald, Thomas; Plettemeier, Dirk; Rucker, Helmut O.; Kurth, William S.
2016-10-01
The experiment Waves aboard the Juno spacecraft, which will arrive at its target planet Jupiter in 2016, was devised to study the plasma and radio waves of the Jovian magnetosphere. We analyzed the Waves antennas, which consist of two nonparallel monopoles operated as a dipole. For this investigation we applied two independent methods: the experimental technique, rheometry, which is based on a downscaled model of the spacecraft to measure the antenna properties in an electrolytic tank and numerical simulations, based on commercial computer codes, from which the quantities of interest (antenna impedances and effective length vectors) are calculated. In this article we focus on the results for the low-frequency range up to about 4 MHz, where the antenna system is in the quasi-static regime. Our findings show that there is a significant deviation of the effective length vectors from the physical monopole directions, caused by the presence of the conducting spacecraft body. The effective axes of the antenna monopoles are offset from the mechanical axes by more than 30°, and effective lengths show a reduction to about 60% of the antenna rod lengths. The antennas' mutual capacitances are small compared to the self-capacitances, and the latter are almost the same for the two monopoles. The overall performance of the antennas in dipole configuration is very stable throughout the frequency range up to about 4-5 MHz and therefore can be regarded as the upper frequency bound below which the presented quasi-static results are applicable.
Network Modeling and Simulation A Practical Perspective
Guizani, Mohsen; Khan, Bilal
2010-01-01
Network Modeling and Simulation is a practical guide to using modeling and simulation to solve real-life problems. The authors give a comprehensive exposition of the core concepts in modeling and simulation, and then systematically address the many practical considerations faced by developers in modeling complex large-scale systems. The authors provide examples from computer and telecommunication networks and use these to illustrate the process of mapping generic simulation concepts to domain-specific problems in different industries and disciplines. Key features: Provides the tools and strate
VHDL simulation with access to transistor models
Gibson, J.
1991-01-01
Hardware description languages such as VHDL have evolved to aid in the design of systems with large numbers of elements and a wide range of electronic and logical abstractions. For high performance circuits, behavioral models may not be able to efficiently include enough detail to give designers confidence in a simulation's accuracy. One option is to provide a link between the VHDL environment and a transistor level simulation environment. The coupling of the Vantage Analysis Systems VHDL simulator and the NOVA simulator provides the combination of VHDL modeling and transistor modeling.
Mortensen, Marianne Foss
of tools and processes to guide the design of educational science exhibits. The guiding paradigm for this development is design-based research, which is characterised by an iterative cycle of design, enactment, and analysis. In the design phase, an educational intervention is planned and carried out based...... on a hypothesised learning process and the means of supporting it. In the enactment phase, the educational intervention is implemented (i.e. the planned lesson is taught, or the museum exhibit is opened to the public). Finally, the analysis phase establishes causality between emergent characteristics...... of the learning outcomes and the design characteristics of the intervention. The analysis process can yield two types of outcomes: Suggestions for the refinement of the specific design in question, and “humble” theory, which is theory that can guide the design of a category of educational interventions...
Modeling and Simulation of Low Voltage Arcs
Ghezzi, L.; Balestrero, A.
2010-01-01
Modeling and Simulation of Low Voltage Arcs is an attempt to improve the physical understanding, mathematical modeling and numerical simulation of the electric arcs that are found during current interruptions in low voltage circuit breakers. An empirical description is gained by refined electrical
Modeling and Simulation of Low Voltage Arcs
Ghezzi, L.; Balestrero, A.
2010-01-01
Modeling and Simulation of Low Voltage Arcs is an attempt to improve the physical understanding, mathematical modeling and numerical simulation of the electric arcs that are found during current interruptions in low voltage circuit breakers. An empirical description is gained by refined electrical m
Whole-building Hygrothermal Simulation Model
Rode, Carsten; Grau, Karl
2003-01-01
An existing integrated simulation tool for dynamic thermal simulation of building was extended with a transient model for moisture release and uptake in building materials. Validation of the new model was begun with comparison against measurements in an outdoor test cell furnished with single mat...
Gielen, A.W.J.
2008-01-01
A well known foam for naval sandwiches is PVC (polyvinyl chloride) foam. This foam exhibits elasto-damage behavior under tension and elasto-plastic behavior under compression. A proper material model is required for the prediction of the failure and post-failure behavior of these sandwiches during (
Whole-building Hygrothermal Simulation Model
Rode, Carsten; Grau, Karl
2003-01-01
An existing integrated simulation tool for dynamic thermal simulation of building was extended with a transient model for moisture release and uptake in building materials. Validation of the new model was begun with comparison against measurements in an outdoor test cell furnished with single...... materials. Almost quasi-steady, cyclic experiments were used to compare the indoor humidity variation and the numerical results of the integrated simulation tool with the new moisture model. Except for the case with chipboard as furnishing, the predictions of indoor humidity with the detailed model were...
Simulation model of metallurgical production management
P. Šnapka
2013-07-01
Full Text Available This article is focused to the problems of the metallurgical production process intensification. The aim is the explaining of simulation model which presents metallurgical production management system adequated to new requirements. The knowledge of a dynamic behavior and features of metallurgical production system and its management are needed to this model creation. Characteristics which determine the dynamics of metallurgical production process are characterized. Simulation model is structured as functional blocks and their linkages with regard to organizational and temporal hierarchy of their actions. The creation of presented simulation model is based on theoretical findings of regulation, hierarchical systems and optimization.
Morra, Edward A; Heim, Christine S; Greenwald, A Seth
2012-09-19
Computational models that predict clinical surface damage of the tibial insert during activities of daily living are emerging as powerful tools to assess the safety and efficacy of contemporary total knee arthroplasty designs. These models have the advantage of quickly determining the performance of new designs at low cost, and they allow direct comparison with the performance of classic, clinically successful designs. This study validated finite element and kinematic modeling predictions through comparison with preclinical physical testing results, damage patterns on retrieved tibial inserts, and clinically measured knee motion. There is a mounting body of evidence to support the role of computational modeling as a preclinical tool that enables the optimization of total knee arthroplasty designs and the auditing of component quality control before large-scale manufacturing is undertaken.
Model-Based Fatigue Prognosis of Fiber-Reinforced Laminates Exhibiting Concurrent Damage Mechanisms
Corbetta, M.; Sbarufatti, C.; Saxena, A.; Giglio, M.; Goebel, K.
2016-01-01
Prognostics of large composite structures is a topic of increasing interest in the field of structural health monitoring for aerospace, civil, and mechanical systems. Along with recent advancements in real-time structural health data acquisition and processing for damage detection and characterization, model-based stochastic methods for life prediction are showing promising results in the literature. Among various model-based approaches, particle-filtering algorithms are particularly capable in coping with uncertainties associated with the process. These include uncertainties about information on the damage extent and the inherent uncertainties of the damage propagation process. Some efforts have shown successful applications of particle filtering-based frameworks for predicting the matrix crack evolution and structural stiffness degradation caused by repetitive fatigue loads. Effects of other damage modes such as delamination, however, are not incorporated in these works. It is well established that delamination and matrix cracks not only co-exist in most laminate structures during the fatigue degradation process but also affect each other's progression. Furthermore, delamination significantly alters the stress-state in the laminates and accelerates the material degradation leading to catastrophic failure. Therefore, the work presented herein proposes a particle filtering-based framework for predicting a structure's remaining useful life with consideration of multiple co-existing damage-mechanisms. The framework uses an energy-based model from the composite modeling literature. The multiple damage-mode model has been shown to suitably estimate the energy release rate of cross-ply laminates as affected by matrix cracks and delamination modes. The model is also able to estimate the reduction in stiffness of the damaged laminate. This information is then used in the algorithms for life prediction capabilities. First, a brief summary of the energy-based damage model
Lisboa, Marcio V.; Aciole, Gilberth T. S.; Oliveira, Susana C. P. S.; Marques, Aparecida M. C.; Baptista, Abrahão F.; Pinheiro, Antonio L. B.; Aguiar, Marcio C.; Santos, Jean N.
2010-05-01
The role of occlusion on Tempormandibular Disorders (TMD) is still unclear, mainly regarding muscular function. The aim of this study was to evaluate the occlusion highlights on masseter ultra morphology. Twenty Wistar rats were randomly divided in four groups: 10 for control group, 10 for occlusal alteration group (CCO). Rats underwent unilateral amputation of the left inferior and superior molar cusps to simulate an occlusal wear situation. The rats of control group had no occlusal wear. Half of the animals of each group was sacrificed in 14 days after the occlusal consuming and half 30 days after the occlusal consuming. The masseter muscles ipsilateral to the amputated molars were excised and processed for light microscopy, electron microscopy. The light microscopy did not show differences between the groups. The electron microscopy was able to detect a degree of intracellular damage in muscle fibers of CCO group: swollen mitochondria with disrupted cristae and cleared matrix, signs of hypercontraction of I bands and myofibril disorganization.
Simulation modeling for the health care manager.
Kennedy, Michael H
2009-01-01
This article addresses the use of simulation software to solve administrative problems faced by health care managers. Spreadsheet add-ins, process simulation software, and discrete event simulation software are available at a range of costs and complexity. All use the Monte Carlo method to realistically integrate probability distributions into models of the health care environment. Problems typically addressed by health care simulation modeling are facility planning, resource allocation, staffing, patient flow and wait time, routing and transportation, supply chain management, and process improvement.
Limi Elizabeth Mathew
2014-12-01
Full Text Available Dolichos biflorus (Muthira is a branched, suberect, and downing herb, native to most parts of India, and found at altitudes of up to 1000 m, whose seeds can be cooked and eaten. Nutrition plays a key role in building immunity and preventing noncommunicable diseases to a certain extent. The purpose of this study was to evaluate the anti-inflammatory and antioxidant effects of 70% methanolic extract of seeds of D. biflorus (DME in carrageenan-induced inflammation. DME exhibited maximum percentage of oedema inhibition at a dose of 50 mg/kg at the 3rd hour of carrageenan induction. The effect was higher than that of the standard drug Voveran. The activities of cyclooxygenase, lipoxygenase, nitric oxide synthase, myeloperoxidase, and malondialdehyde showed significant (p < 0.05 reduction whereas the activities of antioxidant enzymes, vitamins C, and reduced glutathione level were increased significantly (p < 0.05 on treatment with DME. Also levels of the acute phase protein, ceruloplasmin, were brought to their normal range in DME-treated rats. Phytochemical analysis showed that the extract contains alkaloids, flavonoids, carbohydrates, proteins, and tannins, which may contribute to its anti-inflammatory and antioxidant activity. Thus the results demonstrate the potential beneficiary effect of DME on carrageenan-induced inflammation in rats.
Warehouse Simulation Through Model Configuration
Verriet, J.H.; Hamberg, R.; Caarls, J.; Wijngaarden, B. van
2013-01-01
The pre-build development of warehouse systems leads from a specific customer request to a specific customer quotation. This involves a process of configuring a warehouse system using a sequence of steps that contain increasingly more details. Simulation is a helpful tool in analyzing warehouse desi
Modeling and Simulation of Matrix Converter
Liu, Fu-rong; Klumpner, Christian; Blaabjerg, Frede
2005-01-01
This paper discusses the modeling and simulation of matrix converter. Two models of matrix converter are presented: one is based on indirect space vector modulation and the other is based on power balance equation. The basis of these two models is• given and the process on modeling is introduced...
Quantum simulation of the t- J model
Yamaguchi, Fumiko; Yamamoto, Yoshihisa
2002-12-01
Computer simulation of a many-particle quantum system is bound to reach the inevitable limits of its ability as the system size increases. The primary reason for this is that the memory size used in a classical simulator grows polynomially whereas the Hilbert space of the quantum system does so exponentially. Replacing the classical simulator by a quantum simulator would be an effective method of surmounting this obstacle. The prevailing techniques for simulating quantum systems on a quantum computer have been developed for purposes of computing numerical algorithms designed to obtain approximate physical quantities of interest. The method suggested here requires no numerical algorithms; it is a direct isomorphic translation between a quantum simulator and the quantum system to be simulated. In the quantum simulator, physical parameters of the system, which are the fixed parameters of the simulated quantum system, are under the control of the experimenter. A method of simulating a model for high-temperature superconducting oxides, the t- J model, by optical control, as an example of such a quantum simulation, is presented.
CAUSA - An Environment For Modeling And Simulation
Dilger, Werner; Moeller, Juergen
1989-03-01
CAUSA is an environment for modeling and simulation of dynamic systems on a quantitative level. The environment provides a conceptual framework including primitives like objects, processes and causal dependencies which allow the modeling of a broad class of complex systems. The facility of simulation allows the quantitative and qualitative inspection and empirical investigation of the behavior of the modeled system. CAUSA is implemented in Knowledge-Craft and runs on a Symbolics 3640.
A Stochastic model for two-station hydraulics exhibiting transient impact
Jacobsen, Judith L.; Madsen, Henrik; Harremoës, Poul
1997-01-01
The objective of the paper is to interpret data on water level variation in a river affected by overflow from a sewer system during rain. The simplest possible, hydraulic description is combined with stochastic methods for data analysis and model parameter estimation. This combination of determin......The objective of the paper is to interpret data on water level variation in a river affected by overflow from a sewer system during rain. The simplest possible, hydraulic description is combined with stochastic methods for data analysis and model parameter estimation. This combination...
Parallel plate model for trabecular bone exhibits volume fraction-dependant bias
Day, J; Ding, Ming; Odgaard, A;
2000-01-01
Unbiased stereological methods were used in conjunction with microcomputed tomographic (micro-CT) scans of human and animal bone to investigate errors created when the parallel plate model was used to calculate morphometric parameters. Bone samples were obtained from the human proximal tibia......, canine distal femur, rat tail, and pig spine and scanned in a micro-CT scanner. Trabecular thickness, trabecular spacing, and trabecular number were calculated using the parallel plate model. Direct thickness, and spacing and connectivity density were calculated using unbiased three-dimensional methods...
Modeling and Simulation of Matrix Converter
Liu, Fu-rong; Klumpner, Christian; Blaabjerg, Frede
2005-01-01
This paper discusses the modeling and simulation of matrix converter. Two models of matrix converter are presented: one is based on indirect space vector modulation and the other is based on power balance equation. The basis of these two models is• given and the process on modeling is introduced...... in details. The results of simulations developed for different researches reveal that different mdel may be suitable for different purpose, thus the model should be chosen different carefully. Some details and tricks in modeling are also introduced which give a reference for further research....
Simulation-based Manufacturing System Modeling
卫东; 金烨; 范秀敏; 严隽琪
2003-01-01
In recent years, computer simulation appears to be very advantageous technique for researching the resource-constrained manufacturing system. This paper presents an object-oriented simulation modeling method, which combines the merits of traditional methods such as IDEF0 and Petri Net. In this paper, a four-layer-one-angel hierarchical modeling framework based on OOP is defined. And the modeling description of these layers is expounded, such as: hybrid production control modeling and human resource dispatch modeling. To validate the modeling method, a case study of an auto-product line in a motor manufacturing company has been carried out.
Modeling cavities exhibiting strong lateral confinement using open geometry Fourier modal method
Häyrynen, Teppo; Gregersen, Niels
2016-01-01
We have developed a computationally eﬃcient Fourier-Bessel expansion based open geometry formalism for modeling the optical properties of rotationally symmetric photonic nanostructures. The lateral computation domain is assumed inﬁnite so that no artiﬁcial boundary conditions are needed. Instead...
Parallel plate model for trabecular bone exhibits volume fraction-dependent bias
J.S. Day (Judd); M. Ding; A. Odgaard; D.R. Sumner (Dale); I. Hvid (Ivan); H.H. Weinans (Harrie)
2000-01-01
textabstractUnbiased stereological methods were used in conjunction with microcomputed tomographic (micro-CT) scans of human and animal bone to investigate errors created when the parallel plate model was used to calculate morphometric parameters. Bone samples were obtained from the human proximal t
Multiscale Model Approach for Magnetization Dynamics Simulations
De Lucia, Andrea; Tretiakov, Oleg A; Kläui, Mathias
2016-01-01
Simulations of magnetization dynamics in a multiscale environment enable rapid evaluation of the Landau-Lifshitz-Gilbert equation in a mesoscopic sample with nanoscopic accuracy in areas where such accuracy is required. We have developed a multiscale magnetization dynamics simulation approach that can be applied to large systems with spin structures that vary locally on small length scales. To implement this, the conventional micromagnetic simulation framework has been expanded to include a multiscale solving routine. The software selectively simulates different regions of a ferromagnetic sample according to the spin structures located within in order to employ a suitable discretization and use either a micromagnetic or an atomistic model. To demonstrate the validity of the multiscale approach, we simulate the spin wave transmission across the regions simulated with the two different models and different discretizations. We find that the interface between the regions is fully transparent for spin waves with f...
Systematic modelling and simulation of refrigeration systems
Rasmussen, Bjarne D.; Jakobsen, Arne
1998-01-01
The task of developing a simulation model of a refrigeration system can be very difficult and time consuming. In order for this process to be effective, a systematic method for developing the system model is required. This method should aim at guiding the developer to clarify the purpose of the s......The task of developing a simulation model of a refrigeration system can be very difficult and time consuming. In order for this process to be effective, a systematic method for developing the system model is required. This method should aim at guiding the developer to clarify the purpose...... of the simulation, to select appropriate component models and to set up the equations in a well-arranged way. In this paper the outline of such a method is proposed and examples showing the use of this method for simulation of refrigeration systems are given....
Campbell, Stuart G; Hatfield, P Chris; Campbell, Kenneth S
2011-09-01
A skeletal muscle fiber that is stimulated to contract and then stretched from L₁ to L₂ produces more force after the initial transient decays than if it is stimulated at L₂. This behavior has been well studied experimentally, and is known as residual force enhancement. The underlying mechanism remains controversial. We hypothesized that residual force enhancement could reflect mechanical interactions between heterogeneous half-sarcomeres. To test this hypothesis, we subjected a computational model of interacting heterogeneous half-sarcomeres to the same activation and stretch protocols that produce residual force enhancement in real preparations. Following a transient period of elevated force associated with active stretching, the model predicted a slowly decaying force enhancement lasting >30 seconds after stretch. Enhancement was on the order of 13% above isometric tension at the post-stretch muscle length, which agrees well with experimental measurements. Force enhancement in the model was proportional to stretch magnitude but did not depend strongly on the velocity of stretch, also in agreement with experiments. Even small variability in the strength of half-sarcomeres (2.1% standard deviation, normally distributed) was sufficient to produce a 5% force enhancement over isometric tension. Analysis of the model suggests that heterogeneity in half-sarcomeres leads to residual force enhancement by storing strain energy introduced during active stretch in distributions of bound cross-bridges. Complex interactions between the heterogeneous half-sarcomeres then dissipate this stored energy at a rate much slower than isolated cross-bridges would cycle. Given the variations in half-sarcomere length that have been observed in real muscle preparations and the stochastic variability inherent in all biological systems, half-sarcomere heterogeneity cannot be excluded as a contributing source of residual force enhancement.
Cristina García Magro
2015-06-01
Full Text Available Purpose: The aims of the paper is offers a model of analysis which allows to measure the impact on the performance of fairs, as well as the knowledge or not of the motives of participation of the visitors on the part of the exhibitors. Design/methodology: A review of the literature is established concerning two of the principal interested agents, exhibitors and visitors, focusing. The study is focused on the line of investigation referred to the motives of participation or not in a trade show. According to the information thrown by each perspectives of study, a comparative analysis is carried out in order to determine the degree of existing understanding between both. Findings: The trade shows allow to be studied from an integrated strategic marketing approach. The fit model between the reasons for participation of exhibitors and visitors offer information on the lack of an understanding between exhibitors and visitors, leading to dissatisfaction with the participation, a fact that is reflected in the fair success. The model identified shows that a strategic plan must be designed in which the reason for participation of visitor was incorporated as moderating variable of the reason for participation of exhibitors. The article concludes with the contribution of a series of proposals for the improvement of fairground results. Social implications: The fit model that improve the performance of trade shows, implicitly leads to successful achievement of targets for multiple stakeholders beyond the consideration of visitors and exhibitors. Originality/value: The integrated perspective of stakeholders allows the study of the existing relationships between the principal groups of interest, in such a way that, having knowledge on the condition of the question of the trade shows facilitates the task of the investigator in future academic works and allows that the interested groups obtain a better performance to the participation in fairs, as visitor or as
Software-Engineering Process Simulation (SEPS) model
Lin, C. Y.; Abdel-Hamid, T.; Sherif, J. S.
1992-01-01
The Software Engineering Process Simulation (SEPS) model is described which was developed at JPL. SEPS is a dynamic simulation model of the software project development process. It uses the feedback principles of system dynamics to simulate the dynamic interactions among various software life cycle development activities and management decision making processes. The model is designed to be a planning tool to examine tradeoffs of cost, schedule, and functionality, and to test the implications of different managerial policies on a project's outcome. Furthermore, SEPS will enable software managers to gain a better understanding of the dynamics of software project development and perform postmodern assessments.
Systematic modelling and simulation of refrigeration systems
Rasmussen, Bjarne D.; Jakobsen, Arne
1998-01-01
The task of developing a simulation model of a refrigeration system can be very difficult and time consuming. In order for this process to be effective, a systematic method for developing the system model is required. This method should aim at guiding the developer to clarify the purpose...... of the simulation, to select appropriate component models and to set up the equations in a well-arranged way. In this paper the outline of such a method is proposed and examples showing the use of this method for simulation of refrigeration systems are given....
HVDC System Characteristics and Simulation Models
Moon, S.I.; Han, B.M.; Jang, G.S. [Electric Enginnering and Science Research Institute, Seoul (Korea)
2001-07-01
This report deals with the AC-DC power system simulation method by PSS/E and EUROSTAG for the development of a strategy for the reliable operation of the Cheju-Haenam interconnected system. The simulation using both programs is performed to analyze HVDC simulation models. In addition, the control characteristics of the Cheju-Haenam HVDC system as well as Cheju AC system characteristics are described in this work. (author). 104 figs., 8 tabs.
Simulation modeling and analysis with Arena
Tayfur Altiok; Benjamin Melamed [Rutgers University, NJ (United States). Department of Industrial and Systems Engineering
2007-06-15
The textbook which treats the essentials of the Monte Carlo discrete-event simulation methodology, and does so in the context of a popular Arena simulation environment. It treats simulation modeling as an in-vitro laboratory that facilitates the understanding of complex systems and experimentation with what-if scenarios in order to estimate their performance metrics. The book contains chapters on the simulation modeling methodology and the underpinnings of discrete-event systems, as well as the relevant underlying probability, statistics, stochastic processes, input analysis, model validation and output analysis. All simulation-related concepts are illustrated in numerous Arena examples, encompassing production lines, manufacturing and inventory systems, transportation systems, and computer information systems in networked settings. Chapter 13.3.3 is on coal loading operations on barges/tugboats.
Fischer, Audrey; Wolman, Marc; Granato, Michael; Parsons, Michael; McCallion, Andrew S; Proescher, Jody; English, Emily
2015-01-01
Pyridostigmine bromide (PB) is an FDA-approved drug for the treatment of myasthenia gravis and a prophylactic pre-treatment for organophosphate nerve agent poisoning. Current methods for evaluating nerve agent treatments include enzymatic studies and mammalian models. Rapid whole animal screening tools for assessing the effects of nerve agent pre-treatment and post-exposure drugs represent an underdeveloped area of research. We used zebrafish as a model for acute and chronic developmental exposure to PB and two related carbamate acetylcholinesterase (AChE) inhibitors, neostigmine bromide (NB) and physostigmine (PS). Lethal doses and gross morphological phenotypes resulting from exposure to sub-lethal doses of these compounds were determined. Quantitative analyses of motility impairment and AChE enzyme inhibition were used to determine optimal dosing conditions for evaluation of the effects of carbamate exposures on neuronal development; ~50% impairment of response to startle stimuli and >50% inhibition of AChE activity were observed at 80 mMPB, 20 mM NB and 0.1 mM PS. PB induced stunted somite length, but no other phenotypic effects were observed. In contrast, NB and PS induced more severe phenotypic morphological defects than PB as well as neurite outgrowth mislocalization. Additionally, NB induced mislocalization of nicotinic acetylcholine receptors, resulting in impaired synapse formation. Taken together, these data suggest that altered patterns of neuronal connectivity contribute to the developmental neurotoxicity of carbamates and demonstrate the utility of the zebrafish model for distinguishing subtle structure-based differential effects of AChE inhibitors, which include nerve agents, pesticides and drugs. Copyright © 2015 Elsevier Inc. All rights reserved.
Object Oriented Modelling and Dynamical Simulation
Wagner, Falko Jens; Poulsen, Mikael Zebbelin
1998-01-01
This report with appendix describes the work done in master project at DTU.The goal of the project was to develop a concept for simulation of dynamical systems based on object oriented methods.The result was a library of C++-classes, for use when both building componentbased models and when...... onduction simulation experiments....
Modeling and simulation for RF system design
Frevert, Ronny; Jancke, Roland; Knöchel, Uwe; Schwarz, Peter; Kakerow, Ralf; Darianian, Mohsen
2005-01-01
Focusing on RF specific modeling and simulation methods, and system and circuit level descriptions, this work contains application-oriented training material. Accompanied by a CD- ROM, it combines the presentation of a mixed-signal design flow, an introduction into VHDL-AMS and Verilog-A, and the application of commercially available simulators.
Pajtler, Kristian W; Sadowski, Natalie; Ackermann, Sandra; Althoff, Kristina; Schönbeck, Kerstin; Batzke, Katharina; Sch, Simonäfers; Odersky, Andrea; Heukamp, Lukas; Astrahantseff, Kathy; Künkele, Annette; Deubzer, Hedwig E; Schramm, Alexander; Spr, Annikaüssel; Thor, Theresa; Lindner, Sven; Eggert, Angelika; Fischer, Matthias; Schulte, Johannes H
2017-01-01
Polo-like kinase 1 (PLK1) is a serine/threonine kinase that promotes G2/M-phase transition, is expressed in elevated levels in high-risk neuroblastomas and correlates with unfavorable patient outcome. Recently, we and others have presented PLK1 as a potential drug target for neuroblastoma, and reported that the BI2536 PLK1 inhibitor showed antitumoral actvity in preclinical neuroblastoma models. Here we analyzed the effects of GSK461364, a competitive inhibitor for ATP binding to PLK1, on typical tumorigenic properties of preclinical in vitro and in vivo neuroblastoma models. GSK461364 treatment of neuroblastoma cell lines reduced cell viability and proliferative capacity, caused cell cycle arrest and massively induced apoptosis. These phenotypic consequences were induced by treatment in the low-dose nanomolar range, and were independent of MYCN copy number status. GSK461364 treatment strongly delayed established xenograft tumor growth in nude mice, and significantly increased survival time in the treatment group. These preclinical findings indicate PLK1 inhibitors may be effective for patients with high-risk or relapsed neuroblastomas with upregulated PLK1 and might be considered for entry into early phase clinical trials in pediatric patients. PMID:28036269
Siegfried, Robert
2014-01-01
Robert Siegfried presents a framework for efficient agent-based modeling and simulation of complex systems. He compares different approaches for describing structure and dynamics of agent-based models in detail. Based on this evaluation the author introduces the "General Reference Model for Agent-based Modeling and Simulation" (GRAMS). Furthermore he presents parallel and distributed simulation approaches for execution of agent-based models -from small scale to very large scale. The author shows how agent-based models may be executed by different simulation engines that utilize underlying hard
MCMC simulation of GARCH model to forecast network traffic load
Akhter Raza Syed
2012-05-01
Full Text Available The performance of a computer network can be enhanced by increasing number of servers, upgrading the hardware, and gaining additional bandwidth but this solution require the huge amount to invest. In contrast to increasing the bandwidth and hardware resources, network traffic modeling play a significant role in enhancing the network performance. As the emphasis of telecommunication service providers shifted towards the high-speed networks providing integrated services at a prescribed Quality of Service (QoS, the role of accurate traffic models in network design and network simulation becomes ever more crucial. We analyze a traffic volume time series of internet requests made to a workstation. This series exhibits a long-range dependence and self-similarity in large time scale and exhibits multifractal in small time scale. In this paper, for this time series, we proposed Generalized Autoregressive Conditional Heteroscedastic, (GARCH model, and practical techniques for model fitting, Markov Chain Monte Carlo simulation and forecasting issues are demonstrated. The proposed model provides us simple and accurate approach for simulating internet data traffic patterns.
Nemeth, A.A.; Hulscher, S.J.M.H.; Damme, van R.M.J.
2003-01-01
Sand waves form a prominent regular pattern in the offshore seabeds of sandy shallow seas. A two dimensional vertical (2DV) flow and morphological numerical model describing the behaviour of these sand waves has been developed. The model contains the 2DV shallow water equations, with a free water su
Modelling Reactive and Proactive Behaviour in Simulation
Majid, Mazlina Abdul; Aickelin, Uwe
2010-01-01
This research investigated the simulation model behaviour of a traditional and combined discrete event as well as agent based simulation models when modelling human reactive and proactive behaviour in human centric complex systems. A departmental store was chosen as human centric complex case study where the operation system of a fitting room in WomensWear department was investigated. We have looked at ways to determine the efficiency of new management policies for the fitting room operation through simulating the reactive and proactive behaviour of staff towards customers. Once development of the simulation models and their verification had been done, we carried out a validation experiment in the form of a sensitivity analysis. Subsequently, we executed a statistical analysis where the mixed reactive and proactive behaviour experimental results were compared with some reactive experimental results from previously published works. Generally, this case study discovered that simple proactive individual behaviou...
Challenges in SysML Model Simulation
Mara Nikolaidou
2016-07-01
Full Text Available Systems Modeling Language (SysML is a standard proposed by the OMG for systems-of-systems (SoS modeling and engineering. To this end, it provides the means to depict SoS components and their behavior in a hierarchical, multi-layer fashion, facilitating alternative engineering activities, such as system design. To explore the performance of SysML, simulation is one of the preferred methods. There are many efforts targeting simulation code generation from SysML models. Numerous simulation methodologies and tools are employed, while different SysML diagrams are utilized. Nevertheless, this process is not standardized, although most of current approaches tend to follow the same steps, even if they employ different tools. The scope of this paper is to provide a comprehensive understanding of the similarities and differences of existing approaches and identify current challenges in fully automating SysML models simulation process.
SIMULATION MODELING SLOW SPATIALLY HETER- OGENEOUS COAGULATION
P. A. Zdorovtsev
2013-01-01
Full Text Available A new model of spatially inhomogeneous coagulation, i.e. formation of larger clusters by joint interaction of smaller ones, is under study. The results of simulation are compared with known analytical and numerical solutions.
Theory, modeling, and simulation annual report, 1992
1993-05-01
This report briefly discusses research on the following topics: development of electronic structure methods; modeling molecular processes in clusters; modeling molecular processes in solution; modeling molecular processes in separations chemistry; modeling interfacial molecular processes; modeling molecular processes in the atmosphere; methods for periodic calculations on solids; chemistry and physics of minerals; graphical user interfaces for computational chemistry codes; visualization and analysis of molecular simulations; integrated computational chemistry environment; and benchmark computations.
Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation.
Reilly, Patrick; Winston, Charisse N; Baron, Kelsey R; Trejo, Margarita; Rockenstein, Edward M; Akers, Johnny C; Kfoury, Najla; Diamond, Marc; Masliah, Eliezer; Rissman, Robert A; Yuan, Shauna H
2017-10-01
Tauopathies are a class of neurodegenerative diseases, including Alzheimer's disease, frontotemporal dementia and progressive supranuclear palsy, which are associated with the pathological aggregation of tau protein into neurofibrillary tangles (NFT). Studies have characterized tau as a "prion-like" protein given its ability to form distinct, stable amyloid conformations capable of transcellular and multigenerational propagation in clonal fashion. It has been proposed that progression of tauopathy could be due to the prion-like propagation of tau, suggesting the possibility that end-stage pathologies, like NFT formation, may require an instigating event such as tau seeding. To investigate this, we applied a novel human induced pluripotent stem cell (hiPSC) system we have developed to serve as a human neuronal model. We introduced the tau repeat domain (tau-RD) with P301L and V337M (tau-RD-LM) mutations into hiPSC-derived neurons and observed expression of tau-RD at levels similar to total tau in postmortem AD brains. Tau aggregation occurred without the addition of recombinant tau fibrils. The conditioned media from tau-RD cultures contained tau-RD seeds, which were capable of inducing aggregate formation in homotypic mode in non-transduced recipient neuronal cultures. The resultant NFTs were thioflavin-positive, silver stain-positive, and assumed fibrillary appearance on transmission electron microscopy (TEM) with immunogold, which revealed paired helical filament 1 (PHF1)-positive NFTs, representing possible recruitment of endogenous tau in the aggregates. Functionally, expression of tau-RD caused neurotoxicity that manifested as axon retraction, synaptic density reduction, and enlargement of lysosomes. The results of our hiPSC study were reinforced by the observation that Tau-RD-LM is excreted in exosomes, which mediated the transfer of human tau to wild-type mouse neurons in vivo. Our hiPSC human neuronal system provides a model for further studies of tau
Application of Chebyshev Polynomial to simulated modeling
CHI Hai-hong; LI Dian-pu
2006-01-01
Chebyshev polynomial is widely used in many fields, and used usually as function approximation in numerical calculation. In this paper, Chebyshev polynomial expression of the propeller properties across four quadrants is given at first, then the expression of Chebyshev polynomial is transformed to ordinary polynomial for the need of simulation of propeller dynamics. On the basis of it,the dynamical models of propeller across four quadrants are given. The simulation results show the efficiency of mathematical model.
Collisionless Electrostatic Shock Modeling and Simulation
2016-10-21
Briefing Charts 3. DATES COVERED (From - To) 30 September 2016 – 21 October 2016 4. TITLE AND SUBTITLE Collisionless Electrostatic Shock Modeling and...release: distribution unlimited. PA#16490 Air Force Research Laboratory Collisionless Electrostatic Shock Modeling and Simulation Daniel W. Crews In-Space...unlimited. PA#16490 Overview • Motivation and Background • What is a Collisionless Shock Wave? • Features of the Collisionless Shock • The Shock Simulation
Canine parvovirus NS1 protein exhibits anti-tumor activity in a mouse mammary tumor model.
Gupta, Shishir Kumar; Yadav, Pavan Kumar; Gandham, Ravi Kumar; Sahoo, A P; Harish, D R; Singh, Arvind Kumar; Tiwari, A K
2016-02-02
Many viral proteins have the ability to kill tumor cells specifically without harming the normal cells. These proteins, on ectopic expression, cause lysis or induction of apoptosis in the target tumor cells. Parvovirus NS1 is one of such proteins, which is known to kill high proliferating tumor cells. In the present study, we assessed the apoptosis inducing ability of canine parvovirus type 2 NS1 protein (CPV2.NS1) in vitro in 4T1 cells, and found it to cause significant cell death due to induction of apoptosis through intrinsic or mitochondrial pathway. Further, we also evaluated the oncolytic activity of CPV2.NS1 protein in a mouse mammary tumor model. The results suggested that CPV2.NS1 was able to inhibit the growth of 4T1 induced mouse mammary tumor as indicated by significantly reduced tumor volume, mitotic, AgNOR and PCNA indices. Further, inhibition of tumor growth was found to be because of induction of apoptosis in the tumor cells, which was evident by a significant increase in the number of TUNEL positive cells. Further, CPV2.NS1 was also able to stimulate the immune cells against the tumor antigens as indicated by the increased CD4+ and CD8+ counts in the blood of CVP2.NS1 treated mice. Further optimization of the delivery of NS1 protein and use of an adjuvant may further enhance its anti-tumor activity. Copyright © 2015 Elsevier B.V. All rights reserved.
Ts65Dn, a mouse model of Down syndrome, exhibits increased GABAB-induced potassium current.
Best, Tyler K; Siarey, Richard J; Galdzicki, Zygmunt
2007-01-01
Down syndrome (DS) is the most common nonheritable cause of mental retardation. DS is the result of the presence of an extra chromosome 21 and its phenotype may be a consequence of overexpressed genes from that chromosome. One such gene is Kcnj6/Girk2, which encodes the G-protein-coupled inward rectifying potassium channel subunit 2 (GIRK2). We have recently shown that the DS mouse model, Ts65Dn, overexpresses GIRK2 throughout the brain and in particular the hippocampus. Here we report that this overexpression leads to a significant increase ( approximately 2-fold) in GABA(B)-mediated GIRK current in primary cultured hippocampal neurons. The dose response curves for peak and steady-state GIRK current density is significantly shifted left toward lower concentrations of baclofen in Ts65Dn neurons compared with diploid controls, consistent with increased functional expression of GIRK channels. Stationary fluctuation analysis of baclofen-induced GIRK current from Ts65Dn neurons indicated no significant change in single-channel conductance compared with diploid. However, significant increases in GIRK channel density was found in Ts65Dn neurons. In normalized baclofen-induced GIRK current and GIRK current kinetics no difference was found between diploid and Ts65Dn neurons, which suggests unimpaired mechanisms of interaction between GIRK channel and GABA(B) receptor. These results indicate that increased expression of GIRK2 containing channels have functional consequences that likely affect the balance between excitatory and inhibitory neuronal transmission.
Modeling of magnetic particle suspensions for simulations
Satoh, Akira
2017-01-01
The main objective of the book is to highlight the modeling of magnetic particles with different shapes and magnetic properties, to provide graduate students and young researchers information on the theoretical aspects and actual techniques for the treatment of magnetic particles in particle-based simulations. In simulation, we focus on the Monte Carlo, molecular dynamics, Brownian dynamics, lattice Boltzmann and stochastic rotation dynamics (multi-particle collision dynamics) methods. The latter two simulation methods can simulate both the particle motion and the ambient flow field simultaneously. In general, specialized knowledge can only be obtained in an effective manner under the supervision of an expert. The present book is written to play such a role for readers who wish to develop the skill of modeling magnetic particles and develop a computer simulation program using their own ability. This book is therefore a self-learning book for graduate students and young researchers. Armed with this knowledge,...
Modelling and Simulation of Wave Loads
Sørensen, John Dalsgaard; Thoft-Christensen, Palle
A simple model of the wave load on slender members of offshore structures is described. The wave elevation of the sea state is modelled by a stationary Gaussian process. A new procedure to simulate realizations of the wave loads is developed. The simulation method assumes that the wave particle...... velocity can be approximated by a Gaussian Markov process. Known approximate results for the first-passage density or equivalently, the distribution of the extremes of wave loads are presented and compared with rather precise simulation results. It is demonstrated that the approximate results...
Modelling and Simulation of Wave Loads
Sørensen, John Dalsgaard; Thoft-Christensen, Palle
1985-01-01
A simple model of the wave load on stender members of offshore structures is described . The wave elevation of the sea stateis modelled by a stationary Gaussian process. A new procedure to simulate realizations of the wave loads is developed. The simulation method assumes that the wave particle...... velocity can be approximated by a Gaussian Markov process. Known approximate results for the first passage density or equivalently, the distribution of the extremes of wave loads are presented and compared with rather precise simulation results. It is demonstrated that the approximate results...
Modeling and simulation of multiport RF switch
Vijay, J [Student, Department of Instrumentation and Control Engineering, National Institute of Technology, Tiruchirappalli-620015 (India); Saha, Ivan [Scientist, Indian Space Research Organisation (ISRO) (India); Uma, G [Lecturer, Department of Instrumentation and Control Engineering, National Institute of Technology, Tiruchirappalli-620015 (India); Umapathy, M [Assistant Professor, Department of Instrumentation and Control Engineering, National Institute of Technology, Tiruchirappalli-620015 (India)
2006-04-01
This paper describes the modeling and simulation of 'Multi Port RF Switch' where the latching mechanism is realized with two hot arm electro thermal actuators and the switching action is realized with electrostatic actuators. It can act as single pole single thrown as well as single pole multi thrown switch. The proposed structure is modeled analytically and required parameters are simulated using MATLAB. The analytical simulation results are validated using Finite Element Analysis of the same in the COVENTORWARE software.
Modeling and simulation of discrete event systems
Choi, Byoung Kyu
2013-01-01
Computer modeling and simulation (M&S) allows engineers to study and analyze complex systems. Discrete-event system (DES)-M&S is used in modern management, industrial engineering, computer science, and the military. As computer speeds and memory capacity increase, so DES-M&S tools become more powerful and more widely used in solving real-life problems. Based on over 20 years of evolution within a classroom environment, as well as on decades-long experience in developing simulation-based solutions for high-tech industries, Modeling and Simulation of Discrete-Event Systems is the only book on
Traffic Modeling in WCDMA System Level Simulations
无
2002-01-01
Traffic modeling is a crucial element in WCDMA system level simulations. A clear understanding of the nature of traffic in the WCDMA system and subsequent selection of an appropriate random traffic model are critical to the success of the modeling enterprise. The resultant performances will evidently be of a function that our design has been well adapted to the traffic, channel and user mobility models, and these models are also accurate. In this article, our attention will be focused on modeling voice and WWW data traffic with the SBBP model and Victor model respectively.
2000-01-01
Have you ever wondered how the engineers at John C. Stennis Space Center in Hancock County, Miss., test fire a Space Shuttle Main Engine? The Test Control Center exhibit at StenniSphere can answer your questions by simulating the test firing of a Space Shuttle Main Engine. A recreation of one of NASA's test control centers, the exhibit explains and portrays the 'shake, rattle and roar' that happens during a real test firing.
Modeling and simulation of luminescence detection platforms.
Salama, Khaled; Eltoukhy, Helmy; Hassibi, Arjang; El-Gamal, Abbas
2004-06-15
Motivated by the design of an integrated CMOS-based detection platform, a simulation model for CCD and CMOS imager-based luminescence detection systems is developed. The model comprises four parts. The first portion models the process of photon flux generation from luminescence probes using ATP-based and luciferase label-based assay kinetics. An optics simulator is then used to compute the incident photon flux on the imaging plane for a given photon flux and system geometry. Subsequently, the output image is computed using a detailed imaging sensor model that accounts for photodetector spectral response, dark current, conversion gain, and various noise sources. Finally, signal processing algorithms are applied to the image to enhance detection reliability and hence increase the overall system throughput. To validate the model, simulation results are compared to experimental results obtained from a CCD-based system that was built to emulate the integrated CMOS-based platform.
SOFT MODELLING AND SIMULATION IN STRATEGY
Luciano Rossoni
2006-06-01
Full Text Available A certain resistance on the part of the responsible controllers for the strategy exists, in using techniques and tools of modeling and simulation. Many find them excessively complicated, already others see them as rigid and mathematical for excessively for the use of strategies in uncertain and turbulent environments. However, some interpretative boarding that take care of, in part exist, the necessities of these borrowers of decision. The objective of this work is to demonstrate of a clear and simple form, some of the most powerful boarding, methodologies and interpretative tools (soft of modeling and simulation in the business-oriented area of strategy. We will define initially, what they are on models, simulation and some aspects to the modeling and simulation in the strategy area. Later we will see some boarding of modeling soft, that they see the modeling process much more of that simply a mechanical process, therefore, as seen for Simon, the human beings rationally are limited and its decisions are influenced by a series of questions of subjective character, related to the way where it is inserted. Keywords: strategy, modeling and simulation, soft systems methodology, cognitive map, systems dynamics.
Modeling and Simulation of Hydraulic Engine Mounts
DUAN Shanzhong; Marshall McNea
2012-01-01
Hydraulic engine mounts are widely used in automotive powertrains for vibration isolation.A lumped mechanical parameter model is a traditional approach to model and simulate such mounts.This paper presents a dynamical model of a passive hydraulic engine mount with a double-chamber,an inertia track,a decoupler,and a plunger.The model is developed based on analogy between electrical systems and mechanical-hydraulic systems.The model is established to capture both low and high frequency dynatmic behaviors of the hydraulic mount.The model will be further used to find the approximate pulse responses of the mounts in terms of the force transmission and top chamber pressure.The close form solution from the simplifiod linear model may provide some insight into the highly nonlinear behavior of the mounts.Based on the model,computer simulation has been carried out to study dynamic performance of the hydraulic mount.
Modelling and simulating fire tube boiler performance
Sørensen, K.; Condra, T.; Houbak, Niels;
2003-01-01
A model for a flue gas boiler covering the flue gas and the water-/steam side has been formulated. The model has been formulated as a number of sub models that are merged into an overall model for the complete boiler. Sub models have been defined for the furnace, the convection zone (split in 2......: a zone submerged in water and a zone covered by steam), a model for the material in the boiler (the steel) and 2 models for resp. the water/steam zone (the boiling) and the steam. The dynamic model has been developed as a number of Differential-Algebraic-Equation system (DAE). Subsequently Mat......Lab/Simulink has been applied for carrying out the simulations. To be able to verify the simulated results experiments has been carried out on a full scale boiler plant....
Modelling and simulating fire tube boiler performance
Sørensen, Kim; Karstensen, Claus; Condra, Thomas Joseph;
2003-01-01
A model for a ue gas boiler covering the ue gas and the water-/steam side has been formulated. The model has been formulated as a number of sub models that are merged into an overall model for the complete boiler. Sub models have been dened for the furnace, the convection zone (split in 2: a zone...... submerged in water and a zone covered by steam), a model for the material in the boiler (the steel) and 2 models for resp. the water/steam zone (the boiling) and the steam. The dynamic model has been developed as a number of Differential-Algebraic- Equation system (DAE). Subsequently MatLab/Simulink has...... been applied for carrying out the simulations. To be able to verify the simulated results an experiments has been carried out on a full scale boiler plant....
Computer simulations of the random barrier model
Schrøder, Thomas; Dyre, Jeppe
2002-01-01
A brief review of experimental facts regarding ac electronic and ionic conduction in disordered solids is given followed by a discussion of what is perhaps the simplest realistic model, the random barrier model (symmetric hopping model). Results from large scale computer simulations are presented......, focusing on universality of the ac response in the extreme disorder limit. Finally, some important unsolved problems relating to hopping models for ac conduction are listed....
Modeling and simulating of unloading welding transformer
无
2001-01-01
The simulation model of an unloading welding transformer was established on the basis of MATLAB software, and the modeling principle was described in detail in the paper. The model was made up of three sub-models, i.e. the linear inductor sub-model, the non-linear inductor sub-model and series connection sub-model controlled by current, and these sub-models were jointed together by means of segmented linearization. The simulating results showed that, in the conditions of the high convert frequency and the large cross section of the magnet core of a welding transformer, the non-linear inductor sub-model can be substituted by a linear inductor sub-model in the model; and the leakage reactance in the welding transformer is one of the main reasons of producing over-current and over-voltage in the inverter. The simulation results demonstrate that the over-voltage produced by leakage reactance is nearly two times of the input voltage supplied to the transformer, and the lasting time of over-voltage depends on time constant τ1. With reducing of τ1, the amplitude of the over-current will increase, and the lasting time becomes shorter. Contrarily, with increasing of τ1, the amplitude of the over-current will decrease, and the lasting time becomes longer. The model has played the important role for the development of the inverter resistance welding machine.
Lattice Boltzmann modeling of directional wetting: Comparing simulations to experiments
Jansen, H. Patrick; Sotthewes, Kai; van Swigchem, Jeroen; Zandvliet, Harold J. W.; Kooij, E. Stefan
2013-07-01
Lattice Boltzmann Modeling (LBM) simulations were performed on the dynamic behavior of liquid droplets on chemically striped patterned surfaces, ultimately with the aim to develop a predictive tool enabling reliable design of future experiments. The simulations accurately mimic experimental results, which have shown that water droplets on such surfaces adopt an elongated shape due to anisotropic preferential spreading. Details of the contact line motion such as advancing of the contact line in the direction perpendicular to the stripes exhibit pronounced similarities in experiments and simulations. The opposite of spreading, i.e., evaporation of water droplets, leads to a characteristic receding motion first in the direction parallel to the stripes, while the contact line remains pinned perpendicular to the stripes. Only when the aspect ratio is close to unity, the contact line also starts to recede in the perpendicular direction. Very similar behavior was observed in the LBM simulations. Finally, droplet movement can be induced by a gradient in surface wettability. LBM simulations show good semiquantitative agreement with experimental results of decanol droplets on a well-defined striped gradient, which move from high- to low-contact angle surfaces. Similarities and differences for all systems are described and discussed in terms of the predictive capabilities of LBM simulations to model direction wetting.
Revolutions in energy through modeling and simulation
Tatro, M.; Woodard, J.
1998-08-01
The development and application of energy technologies for all aspects from generation to storage have improved dramatically with the advent of advanced computational tools, particularly modeling and simulation. Modeling and simulation are not new to energy technology development, and have been used extensively ever since the first commercial computers were available. However, recent advances in computing power and access have broadened the extent and use, and, through increased fidelity (i.e., accuracy) of the models due to greatly enhanced computing power, the increased reliance on modeling and simulation has shifted the balance point between modeling and experimentation. The complex nature of energy technologies has motivated researchers to use these tools to understand better performance, reliability and cost issues related to energy. The tools originated in sciences such as the strength of materials (nuclear reactor containment vessels); physics, heat transfer and fluid flow (oil production); chemistry, physics, and electronics (photovoltaics); and geosciences and fluid flow (oil exploration and reservoir storage). Other tools include mathematics, such as statistics, for assessing project risks. This paper describes a few advancements made possible by these tools and explores the benefits and costs of their use, particularly as they relate to the acceleration of energy technology development. The computational complexity ranges from basic spreadsheets to complex numerical simulations using hardware ranging from personal computers (PCs) to Cray computers. In all cases, the benefits of using modeling and simulation relate to lower risks, accelerated technology development, or lower cost projects.
Inventory Reduction Using Business Process Reengineering and Simulation Modeling.
1996-12-01
center is analyzed using simulation modeling and business process reengineering (BPR) concepts. The two simulation models were designed and evaluated by...reengineering and simulation modeling offer powerful tools to aid the manager in reducing cycle time and inventory levels.
Simulation and modeling of turbulent flows
Gatski, Thomas B; Lumley, John L
1996-01-01
This book provides students and researchers in fluid engineering with an up-to-date overview of turbulent flow research in the areas of simulation and modeling. A key element of the book is the systematic, rational development of turbulence closure models and related aspects of modern turbulent flow theory and prediction. Starting with a review of the spectral dynamics of homogenous and inhomogeneous turbulent flows, succeeding chapters deal with numerical simulation techniques, renormalization group methods and turbulent closure modeling. Each chapter is authored by recognized leaders in their respective fields, and each provides a thorough and cohesive treatment of the subject.
Modeling & Simulation Executive Agent Panel
2007-11-02
Richard W. ; 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME AND ADDRESS Office of the Oceanographer of the Navy...acquisition, and training communities.” MSEA Role • Facilitator in the project startup phase • Catalyst during development • Certifier in the...ACOUSTIC MODELS Parabolic Equation 5.0 ASTRAL 5.0 ASPM 4.3 Gaussian Ray Bundle 1.0 High Freq Env Acoustic (HFEVA) 1.0 COLOSSUS II 1.0 Low Freq Bottom LOSS
MODELLING, SIMULATING AND OPTIMIZING BOILERS
Sørensen, K.; Condra, T.; Houbak, Niels
2003-01-01
, and the total stress level (i.e. stresses introduced due to internal pressure plus stresses introduced due to temperature gradients) must always be kept below the allowable stress level. In this way, the increased water-/steam space that should allow for better dynamic performance, in the end causes limited...... freedom with respect to dynamic operation of the plant. By means of an objective function including as well the price of the plant as a quantification of the value of dynamic operation of the plant an optimization is carried out. The dynamic model of the boiler plant is applied to define parts...
Modelling, simulating and optimizing Boilers
Sørensen, Kim; Condra, Thomas Joseph; Houbak, Niels
2003-01-01
, and the total stress level (i.e. stresses introduced due to internal pressure plus stresses introduced due to temperature gradients) must always be kept below the allowable stress level. In this way, the increased water-/steam space that should allow for better dynamic performance, in the end causes limited...... freedom with respect to dynamic operation of the plant. By means of an objective function including as well the price of the plant as a quantication of the value of dynamic operation of the plant an optimization is carried out. The dynamic model of the boiler plant is applied to dene parts...
Simulering af dagslys i digitale modeller
Villaume, René Domine; Ørstrup, Finn Rude
2004-01-01
Projektet undersøger via forskellige simuleringer af dagslys, kvaliteten af visualiseringer af komplekse lysforhold i digitale modeller i forbindelse med formidling af arkitektur via nettet. I en digital 3D model af Utzon Associates Paustians hus, simulers naturligt dagslysindfald med forskellig...... Renderingsmetoder som: "shaded render" / ”raytraceing” / "Final Gather / ”Global Illumination”...
Validity of microgravity simulation models on earth
Regnard, J; Heer, M; Drummer, C
2001-01-01
Many studies have used water immersion and head-down bed rest as experimental models to simulate responses to microgravity. However, some data collected during space missions are at variance or in contrast with observations collected from experimental models. These discrepancies could reflect inc...
Molecular simulation and modeling of complex I.
Hummer, Gerhard; Wikström, Mårten
2016-07-01
Molecular modeling and molecular dynamics simulations play an important role in the functional characterization of complex I. With its large size and complicated function, linking quinone reduction to proton pumping across a membrane, complex I poses unique modeling challenges. Nonetheless, simulations have already helped in the identification of possible proton transfer pathways. Simulations have also shed light on the coupling between electron and proton transfer, thus pointing the way in the search for the mechanistic principles underlying the proton pump. In addition to reviewing what has already been achieved in complex I modeling, we aim here to identify pressing issues and to provide guidance for future research to harness the power of modeling in the functional characterization of complex I. This article is part of a Special Issue entitled Respiratory complex I, edited by Volker Zickermann and Ulrich Brandt. Copyright © 2016 Elsevier B.V. All rights reserved.
Hybrid simulation models of production networks
Kouikoglou, Vassilis S
2001-01-01
This book is concerned with a most important area of industrial production, that of analysis and optimization of production lines and networks using discrete-event models and simulation. The book introduces a novel approach that combines analytic models and discrete-event simulation. Unlike conventional piece-by-piece simulation, this method observes a reduced number of events between which the evolution of the system is tracked analytically. Using this hybrid approach, several models are developed for the analysis of production lines and networks. The hybrid approach combines speed and accuracy for exceptional analysis of most practical situations. A number of optimization problems, involving buffer design, workforce planning, and production control, are solved through the use of hybrid models.
Weiland, C.; Chadwick, W. W.; Hanshumaker, W.; Osis, V.; Hamilton, C.
2002-12-01
We have created a new interactive exhibit in which the user can sit down and simulate that they are making a dive to the seafloor with the remotely operated vehicle (ROV) named ROPOS. The exhibit immerses the user in an interactive experience that is naturally fun but also educational. This new public display is located at the Hatfield Marine Science Visitor Center in Newport, Oregon. The exhibit is designed to look like the real ROPOS control console and includes three video monitors, a PC, a DVD player, an overhead speaker, graphic panels, buttons, lights, dials, and a seat in front of a joystick. The dives are based on real seafloor settings at Axial seamount, an active submarine volcano on the Juan de Fuca Ridge (NE Pacific) that is also the location of a seafloor observatory called NeMO. The user can choose between 1 of 3 different dives sites in the caldera of Axial Volcano. Once a dive is chosen, then the user watches ROPOS being deployed and then arrives into a 3-D computer-generated seafloor environment that is based on the real world but is easier to visualize and navigate. Once on the bottom, the user is placed within a 360 degree panorama and can look in all directions by manipulating the joystick. By clicking on markers embedded in the scene, the user can then either move to other panorama locations via movies that travel through the 3-D virtual environment, or they can play video clips from actual ROPOS dives specifically related to that scene. Audio accompanying the video clips informs the user where they are going or what they are looking at. After the user is finished exploring the dive site they end the dive by leaving the bottom and watching the ROV being recovered onto the ship at the surface. The user can then choose a different dive or make the same dive again. Within the three simulated dives there are a total of 6 arrival and departure movies, 7 seafloor panoramas, 12 travel movies, and 23 ROPOS video clips. The exhibit software was created
Majid, Mazlina Abdul; Siebers, Peer-Olaf
2010-01-01
In this paper, we investigate output accuracy for a Discrete Event Simulation (DES) model and Agent Based Simulation (ABS) model. The purpose of this investigation is to find out which of these simulation techniques is the best one for modelling human reactive behaviour in the retail sector. In order to study the output accuracy in both models, we have carried out a validation experiment in which we compared the results from our simulation models to the performance of a real system. Our experiment was carried out using a large UK department store as a case study. We had to determine an efficient implementation of management policy in the store's fitting room using DES and ABS. Overall, we have found that both simulation models were a good representation of the real system when modelling human reactive behaviour.
Power electronics system modeling and simulation
Lai, Jih-Sheng
1994-12-31
This paper introduces control system design based softwares, SIMNON and MATLAB/SIMULINK, for power electronics system simulation. A complete power electronics system typically consists of a rectifier bridge along with its smoothing capacitor, an inverter, and a motor. The system components, featuring discrete or continuous, linear or nonlinear, are modeled in mathematical equations. Inverter control methods,such as pulse-width-modulation and hysteresis current control, are expressed in either computer algorithms or digital circuits. After describing component models and control methods, computer programs are then developed for complete systems simulation. Simulation results are mainly used for studying system performances, such as input and output current harmonics, torque ripples, and speed responses. Key computer programs and simulation results are demonstrated for educational purposes.
Simulation of Gravity Currents Using VOF Model
邹建锋; 黄钰期; 应新亚; 任安禄
2002-01-01
By the Volume of Fluid (VOF) multiphase flow model two-dimensional gravity currents with three phases including air are numerically simulated in this article. The necessity of consideration of turbulence effect for high Reynolds numbers is demonstrated quantitatively by LES (the Large Eddy Simulation) turbulence model. The gravity currents are simulated for h ≠ H as well as h = H, where h is the depth of the gravity current before the release and H is the depth of the intruded fluid. Uprising of swell occurs when a current flows horizontally into another lighter one for h ≠ H. The problems under what condition the uprising of swell occurs and how long it takes are considered in this article. All the simulated results are in reasonable agreement with the experimental results available.
Development of NASA's Models and Simulations Standard
Bertch, William J.; Zang, Thomas A.; Steele, Martin J.
2008-01-01
From the Space Shuttle Columbia Accident Investigation, there were several NASA-wide actions that were initiated. One of these actions was to develop a standard for development, documentation, and operation of Models and Simulations. Over the course of two-and-a-half years, a team of NASA engineers, representing nine of the ten NASA Centers developed a Models and Simulation Standard to address this action. The standard consists of two parts. The first is the traditional requirements section addressing programmatics, development, documentation, verification, validation, and the reporting of results from both the M&S analysis and the examination of compliance with this standard. The second part is a scale for evaluating the credibility of model and simulation results using levels of merit associated with 8 key factors. This paper provides an historical account of the challenges faced by and the processes used in this committee-based development effort. This account provides insights into how other agencies might approach similar developments. Furthermore, we discuss some specific applications of models and simulations used to assess the impact of this standard on future model and simulation activities.
Modelling and Simulation of Crude Oil Dispersion
Abdulfatai JIMOH
2006-01-01
Full Text Available This research work was carried out to develop a model equation for the dispersion of crude oil in water. Seven different crude oils (Bonny Light, Antan Terminal, Bonny Medium, Qua Iboe Light, Brass Light Mbede, Forcados Blend and Heavy H were used as the subject crude oils. The developed model equation in this project which is given as...It was developed starting from the equation for the oil dispersion rate in water which is given as...The developed equation was then simulated with the aid of MathCAD 2000 Professional software. The experimental and model results obtained from the simulation of the model equation were plotted on the same axis against time of dispersion. The model results revealed close fittings between the experimental and the model results because the correlation coefficients and the r-square values calculated using Spreadsheet Program were both found to be unity (1.00.
Simulation Modeling of Software Development Processes
Calavaro, G. F.; Basili, V. R.; Iazeolla, G.
1996-01-01
A simulation modeling approach is proposed for the prediction of software process productivity indices, such as cost and time-to-market, and the sensitivity analysis of such indices to changes in the organization parameters and user requirements. The approach uses a timed Petri Net and Object Oriented top-down model specification. Results demonstrate the model representativeness, and its usefulness in verifying process conformance to expectations, and in performing continuous process improvement and optimization.
Incorporation of RAM techniques into simulation modeling
Nelson, S.C. Jr.; Haire, M.J.; Schryver, J.C.
1995-07-01
This work concludes that reliability, availability, and maintainability (RAM) analytical techniques can be incorporated into computer network simulation modeling to yield an important new analytical tool. This paper describes the incorporation of failure and repair information into network simulation to build a stochastic computer model represents the RAM Performance of two vehicles being developed for the US Army: The Advanced Field Artillery System (AFAS) and the Future Armored Resupply Vehicle (FARV). The AFAS is the US Army`s next generation self-propelled cannon artillery system. The FARV is a resupply vehicle for the AFAS. Both vehicles utilize automation technologies to improve the operational performance of the vehicles and reduce manpower. The network simulation model used in this work is task based. The model programmed in this application requirements a typical battle mission and the failures and repairs that occur during that battle. Each task that the FARV performs--upload, travel to the AFAS, refuel, perform tactical/survivability moves, return to logistic resupply, etc.--is modeled. Such a model reproduces a model reproduces operational phenomena (e.g., failures and repairs) that are likely to occur in actual performance. Simulation tasks are modeled as discrete chronological steps; after the completion of each task decisions are programmed that determine the next path to be followed. The result is a complex logic diagram or network. The network simulation model is developed within a hierarchy of vehicle systems, subsystems, and equipment and includes failure management subnetworks. RAM information and other performance measures are collected which have impact on design requirements. Design changes are evaluated through ``what if`` questions, sensitivity studies, and battle scenario changes.
Testing turbulent closure models with convection simulations
Snellman, J E; Mantere, M J; Rheinhardt, M; Dintrans, B
2012-01-01
Aims: To compare simple analytical closure models of turbulent Boussinesq convection for stellar applications with direct three-dimensional simulations both in homogeneous and inhomogeneous (bounded) setups. Methods: We use simple analytical closure models to compute the fluxes of angular momentum and heat as a function of rotation rate measured by the Taylor number. We also investigate cases with varying angles between the angular velocity and gravity vectors, corresponding to locating the computational domain at different latitudes ranging from the pole to the equator of the star. We perform three-dimensional numerical simulations in the same parameter regimes for comparison. The free parameters appearing in the closure models are calibrated by two fit methods using simulation data. Unique determination of the closure parameters is possible only in the non-rotating case and when the system is placed at the pole. In the other cases the fit procedures yield somewhat differing results. The quality of the closu...
Analyzing Strategic Business Rules through Simulation Modeling
Orta, Elena; Ruiz, Mercedes; Toro, Miguel
Service Oriented Architecture (SOA) holds promise for business agility since it allows business process to change to meet new customer demands or market needs without causing a cascade effect of changes in the underlying IT systems. Business rules are the instrument chosen to help business and IT to collaborate. In this paper, we propose the utilization of simulation models to model and simulate strategic business rules that are then disaggregated at different levels of an SOA architecture. Our proposal is aimed to help find a good configuration for strategic business objectives and IT parameters. The paper includes a case study where a simulation model is built to help business decision-making in a context where finding a good configuration for different business parameters and performance is too complex to analyze by trial and error.
Hemispherical sky simulator for daylighting model studies
Selkowitz, S.
1981-07-01
The design of a 24-foot-diameter hemispherical sky simulator recently completed at LBL is described. The goal was to produce a facility in which large models could be tested; which was suitable for research, teaching, and design; which could provide a uniform sky, an overcast sky, and several clear-sky luminance distributions, as well as accommodating an artificial sun. Initial operating experience with the facility is described, the sky simulator capabilities are reviewed, and its strengths and weaknesses relative to outdoor modeling tests are discussed.
Wind Shear Target Echo Modeling and Simulation
Xiaoyang Liu
2015-01-01
Full Text Available Wind shear is a dangerous atmospheric phenomenon in aviation. Wind shear is defined as a sudden change of speed or direction of the wind. In order to analyze the influence of wind shear on the efficiency of the airplane, this paper proposes a mathematical model of point target rain echo and weather target signal echo based on Doppler effect. The wind field model is developed in this paper, and the antenna model is also studied by using Bessel function. The spectrum distribution of symmetric and asymmetric wind fields is researched by using the mathematical model proposed in this paper. The simulation results are in accordance with radial velocity component, and the simulation results also confirm the correctness of the established model of antenna.
A Modal Model to Simulate Typical Structural Dynamic Nonlinearity
Pacini, Benjamin Robert [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Mayes, Randall L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Roettgen, Daniel R [Univ. of Wisconsin, Madison, WI (United States)
2015-10-01
Some initial investigations have been published which simulate nonlinear response with almost traditional modal models: instead of connecting the modal mass to ground through the traditional spring and damper, a nonlinear Iwan element was added. This assumes that the mode shapes do not change with amplitude and there are no interactions between modal degrees of freedom. This work expands on these previous studies. An impact experiment is performed on a structure which exhibits typical structural dynamic nonlinear response, i.e. weak frequency dependence and strong damping dependence on the amplitude of vibration. Use of low level modal test results in combination with high level impacts are processed using various combinations of modal filtering, the Hilbert Transform and band-pass filtering to develop response data that are then fit with various nonlinear elements to create a nonlinear pseudo-modal model. Simulations of forced response are compared with high level experimental data for various nonlinear element assumptions.
Nuclear reactor core modelling in multifunctional simulators
Puska, E.K. [VTT Energy, Nuclear Energy, Espoo (Finland)
1999-06-01
The thesis concentrates on the development of nuclear reactor core models for the APROS multifunctional simulation environment and the use of the core models in various kinds of applications. The work was started in 1986 as a part of the development of the entire APROS simulation system. The aim was to create core models that would serve in a reliable manner in an interactive, modular and multifunctional simulator/plant analyser environment. One-dimensional and three-dimensional core neutronics models have been developed. Both models have two energy groups and six delayed neutron groups. The three-dimensional finite difference type core model is able to describe both BWR- and PWR-type cores with quadratic fuel assemblies and VVER-type cores with hexagonal fuel assemblies. The one- and three-dimensional core neutronics models can be connected with the homogeneous, the five-equation or the six-equation thermal hydraulic models of APROS. The key feature of APROS is that the same physical models can be used in various applications. The nuclear reactor core models of APROS have been built in such a manner that the same models can be used in simulator and plant analyser applications, as well as in safety analysis. In the APROS environment the user can select the number of flow channels in the three-dimensional reactor core and either the homogeneous, the five- or the six-equation thermal hydraulic model for these channels. The thermal hydraulic model and the number of flow channels have a decisive effect on the calculation time of the three-dimensional core model and thus, at present, these particular selections make the major difference between a safety analysis core model and a training simulator core model. The emphasis on this thesis is on the three-dimensional core model and its capability to analyse symmetric and asymmetric events in the core. The factors affecting the calculation times of various three-dimensional BWR, PWR and WWER-type APROS core models have been
Battery thermal models for hybrid vehicle simulations
Pesaran, Ahmad A.
This paper summarizes battery thermal modeling capabilities for: (1) an advanced vehicle simulator (ADVISOR); and (2) battery module and pack thermal design. The National Renewable Energy Laboratory's (NREL's) ADVISOR is developed in the Matlab/Simulink environment. There are several battery models in ADVISOR for various chemistry types. Each one of these models requires a thermal model to predict the temperature change that could affect battery performance parameters, such as resistance, capacity and state of charges. A lumped capacitance battery thermal model in the Matlab/Simulink environment was developed that included the ADVISOR battery performance models. For thermal evaluation and design of battery modules and packs, NREL has been using various computer aided engineering tools including commercial finite element analysis software. This paper will discuss the thermal ADVISOR battery model and its results, along with the results of finite element modeling that were presented at the workshop on "Development of Advanced Battery Engineering Models" in August 2001.
Kanban simulation model for production process optimization
Golchev Riste
2015-01-01
Full Text Available A long time has passed since the KANBAN system has been established as an efficient method for coping with the excessive inventory. Still, the possibilities for its improvement through its integration with other different approaches should be investigated further. The basic research challenge of this paper is to present benefits of KANBAN implementation supported with Discrete Event Simulation (DES. In that direction, at the beginning, the basics of KANBAN system are presented with emphasis on the information and material flow, together with a methodology for implementation of KANBAN system. Certain analysis on combining the simulation with this methodology is presented. The paper is concluded with a practical example which shows that through understanding the philosophy of the implementation methodology of KANBAN system and the simulation methodology, a simulation model can be created which can serve as a basis for a variety of experiments that can be conducted within a short period of time, resulting with production process optimization.
Mathematical modeling and stochastic simulation of soft materials
Zeng, Yun
Soft materials are all around us; they may appear as consumer products, foods, or biological materials. The interest in studying the properties of soft materials both experimentally and theoretically has steadily increased due to their wide range of industrial applications. One example of a soft material is wormlike micellar solutions. Depending on the temperature and composition, these solvent-surfactant-salt mixtures may exhibit close to mono-exponential or, alternatively, power-law or stretched-exponential stress decay. Of particular interest to this thesis is the development of stochastic models that can capture the stress relaxation behavior of such materials in the small strain limit, which is non-exponential in time as opposed to exponential. Continuous time random walk (CTRW) or subordinated Langevin processes are utilized to model systems exhibiting non-exponential relaxation behavior or anomalous diffusion. Stochastic simulations using the CTRW approach or the subordination method are carried out in this thesis for one-dimensional systems in which the probability density distribution of particle positions is described by a fractional Fokker-Planck equation (FFPE). The equivalence of the CTRW simulation and the subordination simulation with that of the FFPE is analyzed through the simulation of an ensemble of particle trajectories. The simulated particle dynamics suggest that CTRW processes or subordinated Langevin dynamics can be included in soft material mesoscale dynamics to capture the anomalous transport. To model the non-exponential stress relaxation dynamics of soft gel systems (three-dimensional fluids), stochastic models are simulated using transient network theory as developed and combined with the CTRW and subordinated Langevin processes. This approach enables us to connect the microstructural dynamics of certain soft gel-like materials with macroscale experimental observations by examining the material properties under homogeneous shear flow
Nikolakis, Georgios; Seltmann, Holger; Hossini, Amir M; Makrantonaki, Evgenia; Knolle, Jürgen; Zouboulis, Christos C
2015-07-01
The sebaceous gland displays key functions of the human skin, such as hormone synthesis in situ, antimicrobial activity and participation to inflammatory responses. Consequently, there is an emerging need of advanced in vitro models to study complex interactions between the sebaceous gland and the other skin compartments. Despite the evolution of both full-skin organ culture and reconstructed three-dimensional skin models, no satisfactory solutions have been provided for the integration of sebaceous glands and/or sebaceous gland cells in those models, probably due to their problematic maintenance both in vitro and ex vivo. We have developed a coculture model of explant skin in direct contact with immortalized SZ95 sebocytes, which resulted in overall improved structural integrity of the epidermis, higher percentage of proliferating basal epidermal cells and reduced apoptosis of differentiating keratinocytes after 6 days, as detected by Ki67 and TUNEL staining, respectively. Furthermore SZ95 sebocytes exhibited morphological and biochemical signs of normal differentiation and lipid accumulation, while interleukin-6 expression in the supernatant of the cocultures was decreased in comparison with the control. The data provide evidence of a beneficial interaction between sebocytes and skin explants and provide the rationale for their integration in future three-dimensional skin models.
CAMBIO: software for modelling and simulation of bioprocesses.
Farza, M; Chéruy, A
1991-07-01
CAMBIO, a software package devoted to bioprocess modelling, which runs on Apollo computers, is described. This software enables bioengineers to easily and interactively design appropriate mathematical models directly from their perception of the process. CAMBIO provides the user with a set of design symbols and mnemonic icons in order to interactively design a functional diagram. This diagram has to exhibit the most relevant components with their related interactions through biological and physico-chemical reactions. Then, CAMBIO automatically generates the dynamical material balance equations of the process in the form of an algebraic-differential system by taking advantage of the knowledge involved in the functional diagram. The model may be used for control design purpose or completed by kinetics expressions with a view to simulation. CAMBIO offers facilities to generate a simulation model (for coding of kinetics, introducing auxiliary variables, etc.). This model is automatically interfaced with a specialized simulation software which allows an immediate visualization of the process dynamical behaviour under various operational conditions (possibly involving feedback control strategies). An example of an application dealing with yeast fermentation is given.
TRANSFORM - TRANsient Simulation Framework of Reconfigurable Models
2017-09-01
Existing development tools for early stage design and scoping of energy systems are often time consuming to use, proprietary, and do not contain the necessary function to model complete systems (i.e., controls, primary, and secondary systems) in a common platform. The Modelica programming language based TRANSFORM tool (1) provides a standardized, common simulation environment for early design of energy systems (i.e., power plants), (2) provides a library of baseline component modules to be assembled into full plant models using available geometry, design, and thermal-hydraulic data, (3) defines modeling conventions for interconnecting component models, and (4) establishes user interfaces and support tools to facilitate simulation development (i.e., configuration and parameterization), execution, and results display and capture.
EXACT SIMULATION OF A BOOLEAN MODEL
Christian Lantuéjoul
2013-06-01
Full Text Available A Boolean model is a union of independent objects (compact random subsets located at Poisson points. Two algorithms are proposed for simulating a Boolean model in a bounded domain. The first one applies only to stationary models. It generates the objects prior to their Poisson locations. Two examples illustrate its applicability. The second algorithm applies to stationary and non-stationary models. It generates the Poisson points prior to the objects. Its practical difficulties of implementation are discussed. Both algorithms are based on importance sampling techniques, and the generated objects are weighted.
Biological transportation networks: Modeling and simulation
Albi, Giacomo
2015-09-15
We present a model for biological network formation originally introduced by Cai and Hu [Adaptation and optimization of biological transport networks, Phys. Rev. Lett. 111 (2013) 138701]. The modeling of fluid transportation (e.g., leaf venation and angiogenesis) and ion transportation networks (e.g., neural networks) is explained in detail and basic analytical features like the gradient flow structure of the fluid transportation network model and the impact of the model parameters on the geometry and topology of network formation are analyzed. We also present a numerical finite-element based discretization scheme and discuss sample cases of network formation simulations.
Modeling and Simulation of Nuclear Fuel Materials
Devanathan, Ramaswami; Van Brutzel, Laurent; Chartier, Alan; Gueneau, Christine; Mattsson, Ann E.; Tikare, Veena; Bartel, Timothy; Besmann, T. M.; Stan, Marius; Van Uffelen, Paul
2010-10-01
We review the state of modeling and simulation of nuclear fuels with emphasis on the most widely used nuclear fuel, UO2. The hierarchical scheme presented represents a science-based approach to modeling nuclear fuels by progressively passing information in several stages from ab initio to continuum levels. Such an approach is essential to overcome the challenges posed by radioactive materials handling, experimental limitations in modeling extreme conditions and accident scenarios, and the small time and distance scales of fundamental defect processes. When used in conjunction with experimental validation, this multiscale modeling scheme can provide valuable guidance to development of fuel for advanced reactors to meet rising global energy demand.
Simulation modeling of health care policy.
Glied, Sherry; Tilipman, Nicholas
2010-01-01
Simulation modeling of health reform is a standard part of policy development and, in the United States, a required element in enacting health reform legislation. Modelers use three types of basic structures to build models of the health system: microsimulation, individual choice, and cell-based. These frameworks are filled in with data on baseline characteristics of the system and parameters describing individual behavior. Available data on baseline characteristics are imprecise, and estimates of key empirical parameters vary widely. A comparison of estimated and realized consequences of several health reform proposals suggests that models provided reasonably accurate estimates, with confidence bounds of approximately 30%.
Modeling and simulation of epidemic spread
Shatnawi, Maad; Lazarova-Molnar, Sanja; Zaki, Nazar
2013-01-01
and control such epidemics. This paper presents an overview of the epidemic spread modeling and simulation, and summarizes the main technical challenges in this field. It further investigates the most relevant recent approaches carried out towards this perspective and provides a comparison and classification...
Object Oriented Modelling and Dynamical Simulation
Wagner, Falko Jens; Poulsen, Mikael Zebbelin
1998-01-01
This report with appendix describes the work done in master project at DTU.The goal of the project was to develop a concept for simulation of dynamical systems based on object oriented methods.The result was a library of C++-classes, for use when both building componentbased models and when...
Modeling and Simulating Virtual Anatomical Humans
Madehkhaksar, Forough; Luo, Zhiping; Pronost, Nicolas; Egges, Arjan
2014-01-01
This chapter presents human musculoskeletal modeling and simulation as a challenging field that lies between biomechanics and computer animation. One of the main goals of computer animation research is to develop algorithms and systems that produce plausible motion. On the other hand, the main chall
Modeling and Simulation in Healthcare Future Directions
2010-07-13
Quantify performance (Competency - based) 6. Simulate before practice ( Digital Libraries ) Classic Education and Examination What is the REVOLUTION in...av $800,000 yr 2.) Actor patients - $250,000 – $400,000/yr 2. Digital Libraries or synthetic tissue models a. Subscription vs up-front costs
Simulation Versus Models: Which One and When?
Dorn, William S.
1975-01-01
Describes two types of computer-based experiments: simulation (which assumes no student knowledge of the workings of the computer program) is recommended for experiments aimed at inductive reasoning; and modeling (which assumes student understanding of the computer program) is recommended for deductive processes. (MLH)
Love Kills:. Simulations in Penna Ageing Model
Stauffer, Dietrich; Cebrat, Stanisław; Penna, T. J. P.; Sousa, A. O.
The standard Penna ageing model with sexual reproduction is enlarged by adding additional bit-strings for love: Marriage happens only if the male love strings are sufficiently different from the female ones. We simulate at what level of required difference the population dies out.
Inverse modeling for Large-Eddy simulation
Geurts, Bernardus J.
1998-01-01
Approximate higher order polynomial inversion of the top-hat filter is developed with which the turbulent stress tensor in Large-Eddy Simulation can be consistently represented using the filtered field. Generalized (mixed) similarity models are proposed which improved the agreement with the kinetic
Microdata Simulation Modeling After Twenty Years.
Haveman, Robert H.
1986-01-01
This article describes the method and the development of microdata simulation modeling over the past two decades. After tracing a brief history of this evaluation method, its problems and prospects are assessed. The effects of this research method on the development of the social sciences are examined. (JAZ)
Simulation Modeling on the Macintosh using STELLA.
Costanza, Robert
1987-01-01
Describes a new software package for the Apple Macintosh computer which can be used to create elaborate simulation models in a fraction of the time usually required without using a programming language. Illustrates the use of the software which relates to water usage. (TW)
Simulation Modeling of Radio Direction Finding Results
K. Pelikan
1994-12-01
Full Text Available It is sometimes difficult to determine analytically error probabilities of direction finding results for evaluating algorithms of practical interest. Probalistic simulation models are described in this paper that can be to study error performance of new direction finding systems or to geographical modifications of existing configurations.
A Prison/Parole System Simulation Model,
parole system on future prison and parole populations. A simulation model is presented, viewing a prison / parole system as a feedback process for...ciminal offenders . Transitions among the states in which an offender might be located, imprisoned, paroled , and discharged, are assumed to be in...accordance with a discrete time semi-Markov process. Projected prison and parole populations for sample data and applications of the model are discussed. (Author)
Twitter's tweet method modelling and simulation
Sarlis, Apostolos S.; Sakas, Damianos P.; Vlachos, D. S.
2015-02-01
This paper seeks to purpose the concept of Twitter marketing methods. The tools that Twitter provides are modelled and simulated using iThink in the context of a Twitter media-marketing agency. The paper has leveraged the system's dynamic paradigm to conduct Facebook marketing tools and methods modelling, using iThink™ system to implement them. It uses the design science research methodology for the proof of concept of the models and modelling processes. The following models have been developed for a twitter marketing agent/company and tested in real circumstances and with real numbers. These models were finalized through a number of revisions and iterators of the design, develop, simulate, test and evaluate. It also addresses these methods that suit most organized promotion through targeting, to the Twitter social media service. The validity and usefulness of these Twitter marketing methods models for the day-to-day decision making are authenticated by the management of the company organization. It implements system dynamics concepts of Twitter marketing methods modelling and produce models of various Twitter marketing situations. The Tweet method that Twitter provides can be adjusted, depending on the situation, in order to maximize the profit of the company/agent.
Sønderholm, Majken; Kragh, Kasper Nørskov; Koren, Klaus
2017-01-01
Alginate beads represent a simple and highly reproducible in vitro model system for diffusion-limited bacterial growth. In this study, alginate beads were inoculated with Pseudomonas aeruginosa and followed for up to 72 h. Confocal microscopy revealed that P. aeruginosa formed dense clusters...... and reached anoxia ∼100 μm below the alginate bead surface. This gradient was relieved in beads supplemented with NO3− as an alternative electron acceptor allowing for deeper growth into the beads. A comparison of gene expression profiles between planktonic and alginate-encapsulated P. aeruginosa confirmed...... that the bacteria experienced hypoxic and anoxic growth conditions. Furthermore, alginate-encapsulated P. aeruginosa exhibited a lower respiration rate than the planktonic counterpart and showed a high tolerance toward antibiotics. The inoculation and growth of P. aeruginosa in alginate beads represent a simple...
Fault diagnosis based on continuous simulation models
Feyock, Stefan
1987-01-01
The results are described of an investigation of techniques for using continuous simulation models as basis for reasoning about physical systems, with emphasis on the diagnosis of system faults. It is assumed that a continuous simulation model of the properly operating system is available. Malfunctions are diagnosed by posing the question: how can we make the model behave like that. The adjustments that must be made to the model to produce the observed behavior usually provide definitive clues to the nature of the malfunction. A novel application of Dijkstra's weakest precondition predicate transformer is used to derive the preconditions for producing the required model behavior. To minimize the size of the search space, an envisionment generator based on interval mathematics was developed. In addition to its intended application, the ability to generate qualitative state spaces automatically from quantitative simulations proved to be a fruitful avenue of investigation in its own right. Implementations of the Dijkstra transform and the envisionment generator are reproduced in the Appendix.
Modelling and simulation of affinity membrane adsorption.
Boi, Cristiana; Dimartino, Simone; Sarti, Giulio C
2007-08-24
A mathematical model for the adsorption of biomolecules on affinity membranes is presented. The model considers convection, diffusion and adsorption kinetics on the membrane module as well as the influence of dead end volumes and lag times; an analysis of flow distribution on the whole system is also included. The parameters used in the simulations were obtained from equilibrium and dynamic experimental data measured for the adsorption of human IgG on A2P-Sartoepoxy affinity membranes. The identification of a bi-Langmuir kinetic mechanisms for the experimental system investigated was paramount for a correct process description and the simulated breakthrough curves were in good agreement with the experimental data. The proposed model provides a new insight into the phenomena involved in the adsorption on affinity membranes and it is a valuable tool to assess the use of membrane adsorbers in large scale processes.
Multiphase reacting flows modelling and simulation
Marchisio, Daniele L
2007-01-01
The papers in this book describe the most widely applicable modeling approaches and are organized in six groups covering from fundamentals to relevant applications. In the first part, some fundamentals of multiphase turbulent reacting flows are covered. In particular the introduction focuses on basic notions of turbulence theory in single-phase and multi-phase systems as well as on the interaction between turbulence and chemistry. In the second part, models for the physical and chemical processes involved are discussed. Among other things, particular emphasis is given to turbulence modeling strategies for multiphase flows based on the kinetic theory for granular flows. Next, the different numerical methods based on Lagrangian and/or Eulerian schemes are presented. In particular the most popular numerical approaches of computational fluid dynamics codes are described (i.e., Direct Numerical Simulation, Large Eddy Simulation, and Reynolds-Averaged Navier-Stokes approach). The book will cover particle-based meth...
Modeling, simulation and optimization of bipedal walking
Berns, Karsten
2013-01-01
The model-based investigation of motions of anthropomorphic systems is an important interdisciplinary research topic involving specialists from many fields such as Robotics, Biomechanics, Physiology, Orthopedics, Psychology, Neurosciences, Sports, Computer Graphics and Applied Mathematics. This book presents a study of basic locomotion forms such as walking and running is of particular interest due to the high demand on dynamic coordination, actuator efficiency and balance control. Mathematical models and numerical simulation and optimization techniques are explained, in combination with experimental data, which can help to better understand the basic underlying mechanisms of these motions and to improve them. Example topics treated in this book are Modeling techniques for anthropomorphic bipedal walking systems Optimized walking motions for different objective functions Identification of objective functions from measurements Simulation and optimization approaches for humanoid robots Biologically inspired con...
A Superbubble Feedback Model for Galaxy Simulations
Keller, B W; Benincasa, S M; Couchman, H M P
2014-01-01
We present a new stellar feedback model that reproduces superbubbles. Superbubbles from clustered young stars evolve quite differently to individual supernovae and are substantially more efficient at generating gas motions. The essential new components of the model are thermal conduction, sub-grid evaporation and a sub-grid multi-phase treatment for cases where the simulation mass resolution is insufficient to model the early stages of the superbubble. The multi-phase stage is short compared to superbubble lifetimes. Thermal conduction physically regulates the hot gas mass without requiring a free parameter. Accurately following the hot component naturally avoids overcooling. Prior approaches tend to heat too much mass, leaving the hot ISM below $10^6$ K and susceptible to rapid cooling unless ad-hoc fixes were used. The hot phase also allows feedback energy to correctly accumulate from multiple, clustered sources, including stellar winds and supernovae. We employ high-resolution simulations of a single star ...
Estes, Patricia S.; Daniel, Scott G.; Mccallum, Abigail P.; Boehringer, Ashley V.; Sukhina, Alona S.; Zwick, Rebecca A.; Zarnescu, Daniela C.
2013-01-01
SUMMARY Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by complex neuronal and glial phenotypes. Recently, RNA-based mechanisms have been linked to ALS via RNA-binding proteins such as TDP-43, which has been studied in vivo using models ranging from yeast to rodents. We have developed a Drosophila model of ALS based on TDP-43 that recapitulates several aspects of pathology, including motor neuron loss, locomotor dysfunction and reduced survival. Here we report the phenotypic consequences of expressing wild-type and four different ALS-linked TDP-43 mutations in neurons and glia. We show that TDP-43-driven neurodegeneration phenotypes are dose- and age-dependent. In motor neurons, TDP-43 appears restricted to nuclei, which are significantly misshapen due to mutant but not wild-type protein expression. In glia and in the developing neuroepithelium, TDP-43 associates with cytoplasmic puncta. TDP-43-containing RNA granules are motile in cultured motor neurons, although wild-type and mutant variants exhibit different kinetic properties. At the neuromuscular junction, the expression of TDP-43 in motor neurons versus glia leads to seemingly opposite synaptic phenotypes that, surprisingly, translate into comparable locomotor defects. Finally, we explore sleep as a behavioral readout of TDP-43 expression and find evidence of sleep fragmentation consistent with hyperexcitability, a suggested mechanism in ALS. These findings support the notion that although motor neurons and glia are both involved in ALS pathology, at the cellular level they can exhibit different responses to TDP-43. In addition, our data suggest that individual TDP-43 alleles utilize distinct molecular mechanisms, which will be important for developing therapeutic strategies. PMID:23471911
Patricia S. Estes
2013-05-01
Amyotrophic lateral sclerosis (ALS is a fatal disease characterized by complex neuronal and glial phenotypes. Recently, RNA-based mechanisms have been linked to ALS via RNA-binding proteins such as TDP-43, which has been studied in vivo using models ranging from yeast to rodents. We have developed a Drosophila model of ALS based on TDP-43 that recapitulates several aspects of pathology, including motor neuron loss, locomotor dysfunction and reduced survival. Here we report the phenotypic consequences of expressing wild-type and four different ALS-linked TDP-43 mutations in neurons and glia. We show that TDP-43-driven neurodegeneration phenotypes are dose- and age-dependent. In motor neurons, TDP-43 appears restricted to nuclei, which are significantly misshapen due to mutant but not wild-type protein expression. In glia and in the developing neuroepithelium, TDP-43 associates with cytoplasmic puncta. TDP-43-containing RNA granules are motile in cultured motor neurons, although wild-type and mutant variants exhibit different kinetic properties. At the neuromuscular junction, the expression of TDP-43 in motor neurons versus glia leads to seemingly opposite synaptic phenotypes that, surprisingly, translate into comparable locomotor defects. Finally, we explore sleep as a behavioral readout of TDP-43 expression and find evidence of sleep fragmentation consistent with hyperexcitability, a suggested mechanism in ALS. These findings support the notion that although motor neurons and glia are both involved in ALS pathology, at the cellular level they can exhibit different responses to TDP-43. In addition, our data suggest that individual TDP-43 alleles utilize distinct molecular mechanisms, which will be important for developing therapeutic strategies.
Advancing Material Models for Automotive Forming Simulations
Vegter, H.; An, Y.; ten Horn, C. H. L. J.; Atzema, E. H.; Roelofsen, M. E.
2005-08-01
Simulations in automotive industry need more advanced material models to achieve highly reliable forming and springback predictions. Conventional material models implemented in the FEM-simulation models are not capable to describe the plastic material behaviour during monotonic strain paths with sufficient accuracy. Recently, ESI and Corus co-operate on the implementation of an advanced material model in the FEM-code PAMSTAMP 2G. This applies to the strain hardening model, the influence of strain rate, and the description of the yield locus in these models. A subsequent challenge is the description of the material after a change of strain path. The use of advanced high strength steels in the automotive industry requires a description of plastic material behaviour of multiphase steels. The simplest variant is dual phase steel consisting of a ferritic and a martensitic phase. Multiphase materials also contain a bainitic phase in addition to the ferritic and martensitic phase. More physical descriptions of strain hardening than simple fitted Ludwik/Nadai curves are necessary. Methods to predict plastic behaviour of single-phase materials use a simple dislocation interaction model based on the formed cells structures only. At Corus, a new method is proposed to predict plastic behaviour of multiphase materials have to take hard phases into account, which deform less easily. The resulting deformation gradients create geometrically necessary dislocations. Additional micro-structural information such as morphology and size of hard phase particles or grains is necessary to derive the strain hardening models for this type of materials. Measurements available from the Numisheet benchmarks allow these models to be validated. At Corus, additional measured values are available from cross-die tests. This laboratory test can attain critical deformations by large variations in blank size and processing conditions. The tests are a powerful tool in optimising forming simulations
Modelling and simulation of thermal power plants
Eborn, J.
1998-02-01
Mathematical modelling and simulation are important tools when dealing with engineering systems that today are becoming increasingly more complex. Integrated production and recycling of materials are trends that give rise to heterogenous systems, which are difficult to handle within one area of expertise. Model libraries are an excellent way to package engineering knowledge of systems and units to be reused by those who are not experts in modelling. Many commercial packages provide good model libraries, but they are usually domain-specific and closed. Heterogenous, multi-domain systems requires open model libraries written in general purpose modelling languages. This thesis describes a model database for thermal power plants written in the object-oriented modelling language OMOLA. The models are based on first principles. Subunits describe volumes with pressure and enthalpy dynamics and flows of heat or different media. The subunits are used to build basic units such as pumps, valves and heat exchangers which can be used to build system models. Several applications are described; a heat recovery steam generator, equipment for juice blending, steam generation in a sulphuric acid plant and a condensing steam plate heat exchanger. Model libraries for industrial use must be validated against measured data. The thesis describes how parameter estimation methods can be used for model validation. Results from a case-study on parameter optimization of a non-linear drum boiler model show how the technique can be used 32 refs, 21 figs
Dynamics modeling and simulation of flexible airships
Li, Yuwen
The resurgence of airships has created a need for dynamics models and simulation capabilities of these lighter-than-air vehicles. The focus of this thesis is a theoretical framework that integrates the flight dynamics, structural dynamics, aerostatics and aerodynamics of flexible airships. The study begins with a dynamics model based on a rigid-body assumption. A comprehensive computation of aerodynamic effects is presented, where the aerodynamic forces and moments are categorized into various terms based on different physical effects. A series of prediction approaches for different aerodynamic effects are unified and applied to airships. The numerical results of aerodynamic derivatives and the simulated responses to control surface deflection inputs are verified by comparing to existing wind-tunnel and flight test data. With the validated aerodynamics and rigid-body modeling, the equations of motion of an elastic airship are derived by the Lagrangian formulation. The airship is modeled as a free-free Euler-Bernoulli beam and the bending deformations are represented by shape functions chosen as the free-free normal modes. In order to capture the coupling between the aerodynamic forces and the structural elasticity, local velocity on the deformed vehicle is used in the computation of aerodynamic forces. Finally, with the inertial, gravity, aerostatic and control forces incorporated, the dynamics model of a flexible airship is represented by a single set of nonlinear ordinary differential equations. The proposed model is implemented as a dynamics simulation program to analyze the dynamics characteristics of the Skyship-500 airship. Simulation results are presented to demonstrate the influence of structural deformation on the aerodynamic forces and the dynamics behavior of the airship. The nonlinear equations of motion are linearized numerically for the purpose of frequency domain analysis and for aeroelastic stability analysis. The results from the latter for the
Modelling and simulation of surface morphology driven by ion bombardment
Yewande, E.O.
2006-05-02
Non-equilibrium surfaces, at nanometer length scales, externally driven via bombardment with energetic particles are known to exhibit well ordered patterns with a variety of applications in nano-technology. These patterns emerge at time scales on the order of minutes. Continuum theory has been quite successful in giving a general picture of the processes that interplay to give the observed patterns, as well as how such competition might determine the properties of the nanostructures. However, continuum theoretical descriptions are ideal only in the asymptotic limit. The only other theoretical alternative, which happens to be more suitable for the characteristic length-and time-scales of pattern formation, is Monte Carlo simulation. In this thesis, surface morphology is studied using discrete solid-on-solid Monte Carlo models of sputtering and surface diffusion. The simulations are performed in the context of the continuum theories and experiments. In agreement with the experiments, the ripples coarsen with time and the ripple velocity exhibits a power-law behaviour with the ripple wavelength, in addition, the exponent was found to depend on the simulation temperature, which suggests future experimental studies of flux dependence. Moreover, a detailed exploration of possible topographies, for different sputtering conditions, corresponding to different materials, was performed. And different surface topographies e.g. holes, ripples, and dots, were found at oblique incidence, without sample rotation. With sample rotation no new topography was found, its only role being to destroy any inherent anisotropy in the system. (orig.)
Mathematical models and numerical simulation in electromagnetism
Bermúdez, Alfredo; Salgado, Pilar
2014-01-01
The book represents a basic support for a master course in electromagnetism oriented to numerical simulation. The main goal of the book is that the reader knows the boundary-value problems of partial differential equations that should be solved in order to perform computer simulation of electromagnetic processes. Moreover it includes a part devoted to electric circuit theory based on ordinary differential equations. The book is mainly oriented to electric engineering applications, going from the general to the specific, namely, from the full Maxwell’s equations to the particular cases of electrostatics, direct current, magnetostatics and eddy currents models. Apart from standard exercises related to analytical calculus, the book includes some others oriented to real-life applications solved with MaxFEM free simulation software.
Modeling and simulation of economic processes
Bogdan Brumar
2010-12-01
Full Text Available In general, any activity requires a longer action often characterized by a degree of uncertainty, insecurity, in terms of size of the objective pursued. Because of the complexity of real economic systems, the stochastic dependencies between different variables and parameters considered, not all systems can be adequately represented by a model that can be solved by analytical methods and covering all issues for management decision analysis-economic horizon real. Often in such cases, it is considered that the simulation technique is the only alternative available. Using simulation techniques to study real-world systems often requires a laborious work. Making a simulation experiment is a process that takes place in several stages.
First Principles Modelling of Shape Memory Alloys Molecular Dynamics Simulations
Kastner, Oliver
2012-01-01
Materials sciences relate the macroscopic properties of materials to their microscopic structure and postulate the need for holistic multiscale research. The investigation of shape memory alloys is a prime example in this regard. This particular class of materials exhibits strong coupling of temperature, strain and stress, determined by solid state phase transformations of their metallic lattices. The present book presents a collection of simulation studies of this behaviour. Employing conceptually simple but comprehensive models, the fundamental material properties of shape memory alloys are qualitatively explained from first principles. Using contemporary methods of molecular dynamics simulation experiments, it is shown how microscale dynamics may produce characteristic macroscopic material properties. The work is rooted in the materials sciences of shape memory alloys and covers thermodynamical, micro-mechanical and crystallographical aspects. It addresses scientists in these research fields and thei...
Deep Drawing Simulations With Different Polycrystalline Models
Duchêne, Laurent; de Montleau, Pierre; Bouvier, Salima; Habraken, Anne Marie
2004-06-01
The goal of this research is to study the anisotropic material behavior during forming processes, represented by both complex yield loci and kinematic-isotropic hardening models. A first part of this paper describes the main concepts of the `Stress-strain interpolation' model that has been implemented in the non-linear finite element code Lagamine. This model consists of a local description of the yield locus based on the texture of the material through the full constraints Taylor's model. The texture evolution due to plastic deformations is computed throughout the FEM simulations. This `local yield locus' approach was initially linked to the classical isotropic Swift hardening law. Recently, a more complex hardening model was implemented: the physically-based microstructural model of Teodosiu. It takes into account intergranular heterogeneity due to the evolution of dislocation structures, that affects isotropic and kinematic hardening. The influence of the hardening model is compared to the influence of the texture evolution thanks to deep drawing simulations.
Facebook's personal page modelling and simulation
Sarlis, Apostolos S.; Sakas, Damianos P.; Vlachos, D. S.
2015-02-01
In this paper we will try to define the utility of Facebook's Personal Page marketing method. This tool that Facebook provides, is modelled and simulated using iThink in the context of a Facebook marketing agency. The paper has leveraged the system's dynamic paradigm to conduct Facebook marketing tools and methods modelling, using iThink™ system to implement them. It uses the design science research methodology for the proof of concept of the models and modelling processes. The following model has been developed for a social media marketing agent/company, Facebook platform oriented and tested in real circumstances. This model is finalized through a number of revisions and iterators of the design, development, simulation, testing and evaluation processes. The validity and usefulness of this Facebook marketing model for the day-to-day decision making are authenticated by the management of the company organization. Facebook's Personal Page method can be adjusted, depending on the situation, in order to maximize the total profit of the company which is to bring new customers, keep the interest of the old customers and deliver traffic to its website.
Towards Better Coupling of Hydrological Simulation Models
Penton, D.; Stenson, M.; Leighton, B.; Bridgart, R.
2012-12-01
Standards for model interoperability and scientific workflow software provide techniques and tools for coupling hydrological simulation models. However, model builders are yet to realize the benefits of these and continue to write ad hoc implementations and scripts. Three case studies demonstrate different approaches to coupling models, the first using tight interfaces (OpenMI), the second using a scientific workflow system (Trident) and the third using a tailored execution engine (Delft Flood Early Warning System - Delft-FEWS). No approach was objectively better than any other approach. The foremost standard for coupling hydrological models is the Open Modeling Interface (OpenMI), which defines interfaces for models to interact. An implementation of the OpenMI standard involves defining interchange terms and writing a .NET/Java wrapper around the model. An execution wrapper such as OatC.GUI or Pipistrelle executes the models. The team built two OpenMI implementations for eWater Source river system models. Once built, it was easy to swap river system models. The team encountered technical challenges with versions of the .Net framework (3.5 calling 4.0) and with the performance of the execution wrappers when running daily simulations. By design, the OpenMI interfaces are general, leaving significant decisions around the semantics of the interfaces to the implementer. Increasingly, scientific workflow tools such as Kepler, Taverna and Trident are able to replace custom scripts. These tools aim to improve the provenance and reproducibility of processing tasks. In particular, Taverna and the myExperiment website have had success making many bioinformatics workflows reusable and sharable. The team constructed Trident activities for hydrological software including IQQM, REALM and eWater Source. They built an activity generator for model builders to build activities for particular river systems. The models were linked at a simulation level, without any daily time
Modeling and simulation of the human eye
Duran, R.; Ventura, L.; Nonato, L.; Bruno, O.
2007-02-01
The computational modeling of the human eye has been wide studied for different sectors of the scientific and technological community. One of the main reasons for this increasing interest is the possibility to reproduce eye optic properties by means of computational simulations, becoming possible the development of efficient devices to treat and to correct the problems of the vision. This work explores this aspect still little investigated of the modeling of the visual system, considering a computational sketch that make possible the use of real data in the modeling and simulation of the human visual system. This new approach makes possible the individual inquiry of the optic system, assisting in the construction of new techniques used to infer vital data in medical investigations. Using corneal topography to collect real data from patients, a computational model of cornea is constructed and a set of simulations were build to ensure the correctness of the system and to investigate the effect of corneal abnormalities in retinal image formation, such as Plcido Discs, Point Spread Function, Wave front and the projection of a real image and it's visualization on retina.
A superbubble feedback model for galaxy simulations
Keller, B. W.; Wadsley, J.; Benincasa, S. M.; Couchman, H. M. P.
2014-08-01
We present a new stellar feedback model that reproduces superbubbles. Superbubbles from clustered young stars evolve quite differently to individual supernovae and are substantially more efficient at generating gas motions. The essential new components of the model are thermal conduction, subgrid evaporation and a subgrid multiphase treatment for cases where the simulation mass resolution is insufficient to model the early stages of the superbubble. The multiphase stage is short compared to superbubble lifetimes. Thermal conduction physically regulates the hot gas mass without requiring a free parameter. Accurately following the hot component naturally avoids overcooling. Prior approaches tend to heat too much mass, leaving the hot interstellar medium (ISM) below 106 K and susceptible to rapid cooling unless ad hoc fixes were used. The hot phase also allows feedback energy to correctly accumulate from multiple, clustered sources, including stellar winds and supernovae. We employ high-resolution simulations of a single star cluster to show the model is insensitive to numerical resolution, unresolved ISM structure and suppression of conduction by magnetic fields. We also simulate a Milky Way analogue and a dwarf galaxy. Both galaxies show regulated star formation and produce strong outflows.
Theory, modeling and simulation: Annual report 1993
Dunning, T.H. Jr.; Garrett, B.C.
1994-07-01
Developing the knowledge base needed to address the environmental restoration issues of the US Department of Energy requires a fundamental understanding of molecules and their interactions in insolation and in liquids, on surfaces, and at interfaces. To meet these needs, the PNL has established the Environmental and Molecular Sciences Laboratory (EMSL) and will soon begin construction of a new, collaborative research facility devoted to advancing the understanding of environmental molecular science. Research in the Theory, Modeling, and Simulation program (TMS), which is one of seven research directorates in the EMSL, will play a critical role in understanding molecular processes important in restoring DOE`s research, development and production sites, including understanding the migration and reactions of contaminants in soils and groundwater, the development of separation process for isolation of pollutants, the development of improved materials for waste storage, understanding the enzymatic reactions involved in the biodegradation of contaminants, and understanding the interaction of hazardous chemicals with living organisms. The research objectives of the TMS program are to apply available techniques to study fundamental molecular processes involved in natural and contaminated systems; to extend current techniques to treat molecular systems of future importance and to develop techniques for addressing problems that are computationally intractable at present; to apply molecular modeling techniques to simulate molecular processes occurring in the multispecies, multiphase systems characteristic of natural and polluted environments; and to extend current molecular modeling techniques to treat complex molecular systems and to improve the reliability and accuracy of such simulations. The program contains three research activities: Molecular Theory/Modeling, Solid State Theory, and Biomolecular Modeling/Simulation. Extended abstracts are presented for 89 studies.
Simulation modelling of fynbos ecosystems: Systems analysis and conceptual models
Kruger, FJ
1985-03-01
Full Text Available This report outlines progress with the development of computer based dynamic simulation models for ecosystems in the fynbos biome. The models are planned to run on a portable desktop computer with 500 kbytes of memory, extended BASIC language...
A Model Management Approach for Co-Simulation Model Evaluation
Zhang, X.C.; Broenink, Johannes F.; Filipe, Joaquim; Kacprzyk, Janusz; Pina, Nuno
2011-01-01
Simulating formal models is a common means for validating the correctness of the system design and reduce the time-to-market. In most of the embedded control system design, multiple engineering disciplines and various domain-specific models are often involved, such as mechanical, control, software
A transport model for computer simulation of wildfires
Linn, R. [Los Alamos National Lab., NM (United States)
1997-12-31
Realistic self-determining simulation of wildfires is a difficult task because of a large variety of important length scales (including scales on the size of twigs or grass and the size of large trees), imperfect data, complex fluid mechanics and heat transfer, and very complicated chemical reactions. The author uses a transport approach to produce a model that exhibits a self-determining propagation rate. The transport approach allows him to represent a large number of environments such as those with nonhomogeneous vegetation and terrain. He accounts for the microscopic details of a fire with macroscopic resolution by dividing quantities into mean and fluctuating parts similar to what is done in traditional turbulence modeling. These divided quantities include fuel, wind, gas concentrations, and temperature. Reaction rates are limited by the mixing process and not the chemical kinetics. The author has developed a model that includes the transport of multiple gas species, such as oxygen and volatile hydrocarbons, and tracks the depletion of various fuels and other stationary solids and liquids. From this model he develops a simplified local burning model with which he performs a number of simulations that demonstrate that he is able to capture the important physics with the transport approach. With this simplified model he is able to pick up the essence of wildfire propagation, including such features as acceleration when transitioning to upsloping terrain, deceleration of fire fronts when they reach downslopes, and crowning in the presence of high winds.
eShopper modeling and simulation
Petrushin, Valery A.
2001-03-01
The advent of e-commerce gives an opportunity to shift the paradigm of customer communication into a highly interactive mode. The new generation of commercial Web servers, such as the Blue Martini's server, combines the collection of data on a customer behavior with real-time processing and dynamic tailoring of a feedback page. The new opportunities for direct product marketing and cross selling are arriving. The key problem is what kind of information do we need to achieve these goals, or in other words, how do we model the customer? The paper is devoted to customer modeling and simulation. The focus is on modeling an individual customer. The model is based on the customer's transaction data, click stream data, and demographics. The model includes the hierarchical profile of a customer's preferences to different types of products and brands; consumption models for the different types of products; the current focus, trends, and stochastic models for time intervals between purchases; product affinity models; and some generalized features, such as purchasing power, sensitivity to advertising, price sensitivity, etc. This type of model is used for predicting the date of the next visit, overall spending, and spending for different types of products and brands. For some type of stores (for example, a supermarket) and stable customers, it is possible to forecast the shopping lists rather accurately. The forecasting techniques are discussed. The forecasting results can be used for on- line direct marketing, customer retention, and inventory management. The customer model can also be used as a generative model for simulating the customer's purchasing behavior in different situations and for estimating customer's features.
NUMERICAL MODEL APPLICATION IN ROWING SIMULATOR DESIGN
Petr Chmátal
2016-04-01
Full Text Available The aim of the research was to carry out a hydraulic design of rowing/sculling and paddling simulator. Nowadays there are two main approaches in the simulator design. The first one includes a static water with no artificial movement and counts on specially cut oars to provide the same resistance in the water. The second approach, on the other hand uses pumps or similar devices to force the water to circulate but both of the designs share many problems. Such problems are affecting already built facilities and can be summarized as unrealistic feeling, unwanted turbulent flow and bad velocity profile. Therefore, the goal was to design a new rowing simulator that would provide nature-like conditions for the racers and provide an unmatched experience. In order to accomplish this challenge, it was decided to use in-depth numerical modeling to solve the hydraulic problems. The general measures for the design were taken in accordance with space availability of the simulator ́s housing. The entire research was coordinated with other stages of the construction using BIM. The detailed geometry was designed using a numerical model in Ansys Fluent and parametric auto-optimization tools which led to minimum negative hydraulic phenomena and decreased investment and operational costs due to the decreased hydraulic losses in the system.
Advanced Modeling, Simulation and Analysis (AMSA) Capability Roadmap Progress Review
Antonsson, Erik; Gombosi, Tamas
2005-01-01
Contents include the following: NASA capability roadmap activity. Advanced modeling, simulation, and analysis overview. Scientific modeling and simulation. Operations modeling. Multi-special sensing (UV-gamma). System integration. M and S Environments and Infrastructure.
Macro Level Simulation Model Of Space Shuttle Processing
2000-01-01
The contents include: 1) Space Shuttle Processing Simulation Model; 2) Knowledge Acquisition; 3) Simulation Input Analysis; 4) Model Applications in Current Shuttle Environment; and 5) Model Applications for Future Reusable Launch Vehicles (RLV's). This paper is presented in viewgraph form.
Interactive Modelling and Simulation of Human Motion
Engell-Nørregård, Morten Pol
Dansk resumé Denne ph.d.-afhandling beskæftiger sig med modellering og simulation af menneskelig bevægelse. Emnerne i denne afhandling har mindst to ting til fælles. For det første beskæftiger de sig med menneskelig bevægelse. Selv om de udviklede modeller også kan benyttes til andre ting,er det ....... Endvidere kan den anvendes med enhver softbody simuleringsmodel som finite elements eller mass spring systemer. • En kontrol metode til deformerbare legemer baseret på rum tids opti- mering. fremgangsmåden kan anvendes til at styre sammentrækning af muskler i en muskel simulering....
Computer Modelling and Simulation for Inventory Control
G.K. Adegoke
2012-07-01
Full Text Available This study concerns the role of computer simulation as a device for conducting scientific experiments on inventory control. The stores function utilizes a bulk of physical assets and engages a bulk of financial resources in a manufacturing outfit therefore there is a need for an efficient inventory control. The reason being that inventory control reduces cost of production and thereby facilitates the effective and efficient accomplishment of production objectives of an organization. Some mathematical and statistical models were used to compute the Economic Order Quantity (EOQ. Test data were gotten from a manufacturing company and same were simulated. The results generated were used to predict a real life situation and have been presented and discussed. The language of implementation for the three models is Turbo Pascal due to its capability, generality and flexibility as a scientific programming language.
Model parameters for simulation of physiological lipids
McGlinchey, Nicholas
2016-01-01
Coarse grain simulation of proteins in their physiological membrane environment can offer insight across timescales, but requires a comprehensive force field. Parameters are explored for multicomponent bilayers composed of unsaturated lipids DOPC and DOPE, mixed‐chain saturation POPC and POPE, and anionic lipids found in bacteria: POPG and cardiolipin. A nonbond representation obtained from multiscale force matching is adapted for these lipids and combined with an improved bonding description of cholesterol. Equilibrating the area per lipid yields robust bilayer simulations and properties for common lipid mixtures with the exception of pure DOPE, which has a known tendency to form nonlamellar phase. The models maintain consistency with an existing lipid–protein interaction model, making the force field of general utility for studying membrane proteins in physiologically representative bilayers. © 2016 The Authors. Journal of Computational Chemistry Published by Wiley Periodicals, Inc. PMID:26864972
Theory, Modeling and Simulation Annual Report 2000
Dixon, David A.; Garrett, Bruce C.; Straatsma, Tp; Jones, Donald R.; Studham, Ronald S.; Harrison, Robert J.; Nichols, Jeffrey A.
2001-11-01
This annual report describes the 2000 research accomplishments for the Theory, Modeling, and Simulation (TM&S) directorate, one of the six research organizations in the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) at Pacific Northwest National Laboratory (PNNL). EMSL is a U.S. Department of Energy (DOE) national scientific user facility and is the centerpiece of the DOE commitment to providing world-class experimental, theoretical, and computational capabilities for solving the nation's environmental problems.
Theory, Modeling and Simulation Annual Report 2000
Dixon, David A; Garrett, Bruce C; Straatsma, TP; Jones, Donald R; Studham, Scott; Harrison, Robert J; Nichols, Jeffrey A
2001-11-01
This annual report describes the 2000 research accomplishments for the Theory, Modeling, and Simulation (TM and S) directorate, one of the six research organizations in the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) at Pacific Northwest National Laboratory (PNNL). EMSL is a U.S. Department of Energy (DOE) national scientific user facility and is the centerpiece of the DOE commitment to providing world-class experimental, theoretical, and computational capabilities for solving the nation's environmental problems.
Catalog of Wargaming and Military Simulation Models
1992-02-07
PROPONENT: USAF ASD, McDonnell Douglas Corp. POINT OF CONTACT: Photon Research Associates (Alias): Mr. Jeff Johnson , (619) 455-9741; McDonnell Douglas...POINTOF CONTACT: Dr. R. Johnson , (DSN) 295-1593 or (301) 295-1593. PURPOSE: The model provides simulation of airland activities in a theater of operations...training, and education. PROPONENT: J-8 Political Military Affairs Directorate. POINT OF CONTACT: LTC Steven G. Stainer . PURPOSE: RDSS is a system
Fully Adaptive Radar Modeling and Simulation Development
2017-04-01
Organization (NATO) Sensors Electronics Technology (SET)-227 Panel on Cognitive Radar. The FAR M&S architecture developed in Phase I allows for...Air Force’s previously developed radar M&S tools. This report is organized as follows. In Chapter 3, we provide an overview of the FAR framework...AFRL-RY-WP-TR-2017-0074 FULLY ADAPTIVE RADAR MODELING AND SIMULATION DEVELOPMENT Kristine L. Bell and Anthony Kellems Metron, Inc
Difficulties with True Interoperability in Modeling & Simulation
2011-12-01
Standards in M&S cover multiple layers of technical abstraction. There are middleware specifica- tions, such as the High Level Architecture (HLA) ( IEEE Xplore ... IEEE Xplore Digital Library. 2010. 1516-2010 IEEE Standard for Modeling and Simulation (M&S) High Level Architecture (HLA) – Framework and Rules...using different communication protocols being able to allow da- 2642978-1-4577-2109-0/11/$26.00 ©2011 IEEE Report Documentation Page Form ApprovedOMB No
Modelling interplanetary CMEs using magnetohydrodynamic simulations
P. J. Cargill
Full Text Available The dynamics of Interplanetary Coronal Mass Ejections (ICMEs are discussed from the viewpoint of numerical modelling. Hydrodynamic models are shown to give a good zero-order picture of the plasma properties of ICMEs, but they cannot model the important magnetic field effects. Results from MHD simulations are shown for a number of cases of interest. It is demonstrated that the strong interaction of the ICME with the solar wind leads to the ICME and solar wind velocities being close to each other at 1 AU, despite their having very different speeds near the Sun. It is also pointed out that this interaction leads to a distortion of the ICME geometry, making cylindrical symmetry a dubious assumption for the CME field at 1 AU. In the presence of a significant solar wind magnetic field, the magnetic fields of the ICME and solar wind can reconnect with each other, leading to an ICME that has solar wind-like field lines. This effect is especially important when an ICME with the right sense of rotation propagates down the heliospheric current sheet. It is also noted that a lack of knowledge of the coronal magnetic field makes such simulations of little use in space weather forecasts that require knowledge of the ICME magnetic field strength.
Key words. Interplanetary physics (interplanetary magnetic fields Solar physics, astrophysics, and astronomy (flares and mass ejections Space plasma physics (numerical simulation studies
Interactive Modelling and Simulation of Human Motion
Engell-Nørregård, Morten Pol
Dansk resumé Denne ph.d.-afhandling beskæftiger sig med modellering og simulation af menneskelig bevægelse. Emnerne i denne afhandling har mindst to ting til fælles. For det første beskæftiger de sig med menneskelig bevægelse. Selv om de udviklede modeller også kan benyttes til andre ting,er det...... menneskers led, der udviser både ikke-konveksitet og flere frihedsgrader • En generel og alsidig model for aktivering af bløde legemer. Modellen kan anvendes som et animations værktøj, men er lige så velegnet til simulering af menneskelige muskler, da den opfylder de grundlæggende fysiske principper...... primære fokus på at modellere den menneskelige krop. For det andet, beskæftiger de sig alle med simulering som et redskab til at syntetisere bevægelse og dermed skabe animationer. Dette er en vigtigt pointe, da det betyder, at vi ikke kun skaber værktøjer til animatorer, som de kan bruge til at lave sjove...
Progress in Modeling and Simulation of Batteries
Turner, John A [ORNL
2016-01-01
Modeling and simulation of batteries, in conjunction with theory and experiment, are important research tools that offer opportunities for advancement of technologies that are critical to electric motors. The development of data from the application of these tools can provide the basis for managerial and technical decision-making. Together, these will continue to transform batteries for electric vehicles. This collection of nine papers presents the modeling and simulation of batteries and the continuing contribution being made to this impressive progress, including topics that cover: * Thermal behavior and characteristics * Battery management system design and analysis * Moderately high-fidelity 3D capabilities * Optimization Techniques and Durability As electric vehicles continue to gain interest from manufacturers and consumers alike, improvements in economy and affordability, as well as adoption of alternative fuel sources to meet government mandates are driving battery research and development. Progress in modeling and simulation will continue to contribute to battery improvements that deliver increased power, energy storage, and durability to further enhance the appeal of electric vehicles.
Leonardo Leiderman
1992-03-01
Full Text Available Simulating an Optimizing Model of Currency Substitution This paper reports simulations based on the parameter estimates of an intertemporal model of currency substitution under nonexpected utility obtained by Bufman and Leiderman (1991. Here we first study the quantitative impact of changes in the degree of dollarization and in the elasticity of currency substitution on government seigniorage. Then, when examine whether the model can account for the comovement of consumption growth and assets' returnr after the 1985 stabilization program, and in particular for the consumption boom of 1986-87. The results are generally encouraging for future applications of optimizing models of currencysubstitution to policy and practical issues.
Computer Models Simulate Fine Particle Dispersion
2010-01-01
Through a NASA Seed Fund partnership with DEM Solutions Inc., of Lebanon, New Hampshire, scientists at Kennedy Space Center refined existing software to study the electrostatic phenomena of granular and bulk materials as they apply to planetary surfaces. The software, EDEM, allows users to import particles and obtain accurate representations of their shapes for modeling purposes, such as simulating bulk solids behavior, and was enhanced to be able to more accurately model fine, abrasive, cohesive particles. These new EDEM capabilities can be applied in many industries unrelated to space exploration and have been adopted by several prominent U.S. companies, including John Deere, Pfizer, and Procter & Gamble.
Consolidation modelling for thermoplastic composites forming simulation
Xiong, H.; Rusanov, A.; Hamila, N.; Boisse, P.
2016-10-01
Pre-impregnated thermoplastic composites are widely used in the aerospace industry for their excellent mechanical properties, Thermoforming thermoplastic prepregs is a fast manufacturing process, the automotive industry has shown increasing interest in this manufacturing processes, in which the reconsolidation is an essential stage. The model of intimate contact is investigated as the consolidation model, compression experiments have been launched to identify the material parameters, several numerical tests show the influents of the temperature and pressure applied during processing. Finally, a new solid-shell prismatic element has been presented for the simulation of consolidation step in the thermoplastic composites forming process.
Modeling and simulation of reactive flows
Bortoli, De AL; Pereira, Felipe
2015-01-01
Modelling and Simulation of Reactive Flows presents information on modeling and how to numerically solve reactive flows. The book offers a distinctive approach that combines diffusion flames and geochemical flow problems, providing users with a comprehensive resource that bridges the gap for scientists, engineers, and the industry. Specifically, the book looks at the basic concepts related to reaction rates, chemical kinetics, and the development of reduced kinetic mechanisms. It considers the most common methods used in practical situations, along with equations for reactive flows, and va
Solar Electric Bicycle Body Modeling and Simulation
Zhikun Wang
2013-10-01
Full Text Available A new solar electric bicycle design and study were carried out on in this paper. Application of CAD technology to establish three-dimension geometric model, using the kinetic analysis on the frame and other parts for numerical simulation and static strength analysis for the vehicle model design, virtual assembly, complete frame dynamics analysis and vibration analysis, with considering other factors, first on the frame structure improvement, second on security of design calculation analysis and comparison, finally get the ideal body design.
Viscoelastic flow simulations in model porous media
De, S.; Kuipers, J. A. M.; Peters, E. A. J. F.; Padding, J. T.
2017-05-01
We investigate the flow of unsteadfy three-dimensional viscoelastic fluid through an array of symmetric and asymmetric sets of cylinders constituting a model porous medium. The simulations are performed using a finite-volume methodology with a staggered grid. The solid-fluid interfaces of the porous structure are modeled using a second-order immersed boundary method [S. De et al., J. Non-Newtonian Fluid Mech. 232, 67 (2016), 10.1016/j.jnnfm.2016.04.002]. A finitely extensible nonlinear elastic constitutive model with Peterlin closure is used to model the viscoelastic part. By means of periodic boundary conditions, we model the flow behavior for a Newtonian as well as a viscoelastic fluid through successive contractions and expansions. We observe the presence of counterrotating vortices in the dead ends of our geometry. The simulations provide detailed insight into how flow structure, viscoelastic stresses, and viscoelastic work change with increasing Deborah number De. We observe completely different flow structures and different distributions of the viscoelastic work at high De in the symmetric and asymmetric configurations, even though they have the exact same porosity. Moreover, we find that even for the symmetric contraction-expansion flow, most energy dissipation is occurring in shear-dominated regions of the flow domain, not in extensional-flow-dominated regions.
LISP based simulation generators for modeling complex space processes
Tseng, Fan T.; Schroer, Bernard J.; Dwan, Wen-Shing
1987-01-01
The development of a simulation assistant for modeling discrete event processes is presented. Included are an overview of the system, a description of the simulation generators, and a sample process generated using the simulation assistant.
Biomedical Simulation Models of Human Auditory Processes
Bicak, Mehmet M. A.
2012-01-01
Detailed acoustic engineering models that explore noise propagation mechanisms associated with noise attenuation and transmission paths created when using hearing protectors such as earplugs and headsets in high noise environments. Biomedical finite element (FE) models are developed based on volume Computed Tomography scan data which provides explicit external ear, ear canal, middle ear ossicular bones and cochlea geometry. Results from these studies have enabled a greater understanding of hearing protector to flesh dynamics as well as prioritizing noise propagation mechanisms. Prioritization of noise mechanisms can form an essential framework for exploration of new design principles and methods in both earplug and earcup applications. These models are currently being used in development of a novel hearing protection evaluation system that can provide experimentally correlated psychoacoustic noise attenuation. Moreover, these FE models can be used to simulate the effects of blast related impulse noise on human auditory mechanisms and brain tissue.
Simulation Model of Brushless Excitation System
Ahmed N.A. Alla
2007-01-01
Full Text Available Excitation system is key element in the dynamic performance of electric power systems, accurate excitation models are of great importance in simulating and investigating the power system transient phenomena. Parameter identification of the Brushless excitation system was presented. First a block diagram for the EXS parameter was proposed based on the documents and maps in the power station. To identify the parameters of this model, a test procedure to obtain step response, was presented. Using the Genetic Algorithm with the Matlab-software it was possible to identify all the necessary parameters of the model. Using the same measured input signals the response from the standard model showed nearly the same behavior as the excitation system.
Modeling and simulation of direct contact evaporators
F.B. Campos
2001-09-01
Full Text Available A dynamic model of a direct contact evaporator was developed and coupled to a recently developed superheated bubble model. The latter model takes into account heat and mass transfer during the bubble formation and ascension stages and is able to predict gas holdup in nonisothermal systems. The results of the coupled model, which does not have any adjustable parameter, were compared with experimental data. The transient behavior of the liquid-phase temperature and the vaporization rate under quasi-steady-state conditions were in very good agreement with experimental data. The transient behavior of liquid height was only reasonably simulated. In order to explain this partial disagreement, some possible causes were analyzed.
Efficient Turbulence Modeling for CFD Wake Simulations
van der Laan, Paul
, that can accurately and efficiently simulate wind turbine wakes. The linear k-ε eddy viscosity model (EVM) is a popular turbulence model in RANS; however, it underpredicts the velocity wake deficit and cannot predict the anisotropic Reynolds-stresses in the wake. In the current work, nonlinear eddy...... viscosity models (NLEVM) are applied to wind turbine wakes. NLEVMs can model anisotropic turbulence through a nonlinear stress-strain relation, and they can improve the velocity deficit by the use of a variable eddy viscosity coefficient, that delays the wake recovery. Unfortunately, all tested NLEVMs show...... numerically unstable behavior for fine grids, which inhibits a grid dependency study for numerical verification. Therefore, a simpler EVM is proposed, labeled as the k-ε - fp EVM, that has a linear stress-strain relation, but still has a variable eddy viscosity coefficient. The k-ε - fp EVM is numerically...
Integrating Visualizations into Modeling NEST Simulations.
Nowke, Christian; Zielasko, Daniel; Weyers, Benjamin; Peyser, Alexander; Hentschel, Bernd; Kuhlen, Torsten W
2015-01-01
Modeling large-scale spiking neural networks showing realistic biological behavior in their dynamics is a complex and tedious task. Since these networks consist of millions of interconnected neurons, their simulation produces an immense amount of data. In recent years it has become possible to simulate even larger networks. However, solutions to assist researchers in understanding the simulation's complex emergent behavior by means of visualization are still lacking. While developing tools to partially fill this gap, we encountered the challenge to integrate these tools easily into the neuroscientists' daily workflow. To understand what makes this so challenging, we looked into the workflows of our collaborators and analyzed how they use the visualizations to solve their daily problems. We identified two major issues: first, the analysis process can rapidly change focus which requires to switch the visualization tool that assists in the current problem domain. Second, because of the heterogeneous data that results from simulations, researchers want to relate data to investigate these effectively. Since a monolithic application model, processing and visualizing all data modalities and reflecting all combinations of possible workflows in a holistic way, is most likely impossible to develop and to maintain, a software architecture that offers specialized visualization tools that run simultaneously and can be linked together to reflect the current workflow, is a more feasible approach. To this end, we have developed a software architecture that allows neuroscientists to integrate visualization tools more closely into the modeling tasks. In addition, it forms the basis for semantic linking of different visualizations to reflect the current workflow. In this paper, we present this architecture and substantiate the usefulness of our approach by common use cases we encountered in our collaborative work.
Integrating Visualizations into Modeling NEST Simulations
Christian eNowke
2015-12-01
Full Text Available Modeling large-scale spiking neural networks showing realistic biological behavior in their dynamics is a complex and tedious task. Since these networks consist of millions of interconnected neurons, their simulation produces an immense amount of data. In recent years it has become possible to simulate even larger networks. However, solutions to assist researchers in understanding the simulation's complex emergent behavior by means of visualization are still lacking. While developing tools to partially fill this gap, we encountered the challenge to integrate these tools easily into the neuroscientists' daily workflow. To understand what makes this so challenging, we looked into the workflows of our collaborators and analyzed how they use the visualizations to solve their daily problems. We identified two major issues: first, the analysis process can rapidly change focus which requires to switch the visualization tool that assists in the current problem domain. Second, because of the heterogeneous data that results from simulations, researchers want to relate data to investigate these effectively. Since a monolithic application model, processing and visualizing all data modalities and reflecting all combinations of possible workflows in a holistic way, is most likely impossible to develop and to maintain, a software architecture that offers specialized visualization tools that run simultaneously and can be linked together to reflect the current workflow, is a more feasible approach. To this end, we have developed a software architecture that allows neuroscientists to integrate visualization tools more closely into the modeling tasks. In addition, it forms the basis for semantic linking of different visualizations to reflect the current workflow. In this paper, we present this architecture and substantiate the usefulness of our approach by common use cases we encountered in our collaborative work.
Laura Zambonin
2012-01-01
Full Text Available Caffeic, syringic, and protocatechuic acids are phenolic acids derived directly from food intake or come from the gut metabolism of polyphenols. In this study, the antioxidant activity of these compounds was at first evaluated in membrane models, where caffeic acid behaved as a very effective chain-breaking antioxidant, whereas syringic and protocatechuic acids were only retardants of lipid peroxidation. However, all three compounds acted as good scavengers of reactive species in cultured cells subjected to exogenous oxidative stress produced by low level of H2O2. Many tumour cells are characterised by increased ROS levels compared with their noncancerous counterparts. Therefore, we investigated whether phenolic acids, at low concentrations, comparable to those present in human plasma, were able to decrease basal reactive species. Results show that phenolic acids reduced ROS in a leukaemia cell line (HEL, whereas no effect was observed in normal cells, such as HUVEC. The compounds exhibited no toxicity to normal cells while they decreased proliferation in leukaemia cells, inducing apoptosis. In the debate on optimal ROS-manipulating strategies in cancer therapy, our work in leukaemia cells supports the antioxidant ROS-depleting approach.
Simulation modeling for microbial risk assessment.
Cassin, M H; Paoli, G M; Lammerding, A M
1998-11-01
Quantitative microbial risk assessment implies an estimation of the probability and impact of adverse health outcomes due to microbial hazards. In the case of food safety, the probability of human illness is a complex function of the variability of many parameters that influence the microbial environment, from the production to the consumption of a food. The analytical integration required to estimate the probability of foodborne illness is intractable in all but the simplest of models. Monte Carlo simulation is an alternative to computing analytical solutions. In some cases, a risk assessment may be commissioned to serve a larger purpose than simply the estimation of risk. A Monte Carlo simulation can provide insights into complex processes that are invaluable, and otherwise unavailable, to those charged with the task of risk management. Using examples from a farm-to-fork model of the fate of Escherichia coli O157:H7 in ground beef hamburgers, this paper describes specifically how such goals as research prioritization, risk-based characterization of control points, and risk-based comparison of intervention strategies can be objectively achieved using Monte Carlo simulation.
Application of simulation models for the optimization of business processes
Jašek, Roman; Sedláček, Michal; Chramcov, Bronislav; Dvořák, Jiří
2016-06-01
The paper deals with the applications of modeling and simulation tools in the optimization of business processes, especially in solving an optimization of signal flow in security company. As a modeling tool was selected Simul8 software that is used to process modeling based on discrete event simulation and which enables the creation of a visual model of production and distribution processes.
Raytracing simulations of coupled dark energy models
Pace, Francesco; Moscardini, Lauro; Bacon, David; Crittenden, Robert
2014-01-01
Dark matter and dark energy are usually assumed to be independent, coupling only gravitationally. An extension to this simple picture is to model dark energy as a scalar field which is directly coupled to the cold dark matter fluid. Such a non-trivial coupling in the dark sector leads to a fifth force and a time-dependent dark matter particle mass. In this work we examine the impact that dark energy-dark matter couplings have on weak lensing statistics by constructing realistic simulated weak-lensing maps using raytracing techniques through a suite of N-body cosmological simulations. We construct maps for an array of different lensing quantities, covering a range of scales from a few arcminutes to several degrees. The concordance $\\Lambda$CDM model is compared to different coupled dark energy models, described either by an exponential scalar field potential (standard coupled dark energy scenario) or by a SUGRA potential (bouncing model). We analyse several statistical quantities, in particular the power spect...
Closed loop models for analyzing engineering requirements for simulators
Baron, S.; Muralidharan, R.; Kleinman, D.
1980-01-01
A closed loop analytic model, incorporating a model for the human pilot, (namely, the optimal control model) that would allow certain simulation design tradeoffs to be evaluated quantitatively was developed. This model was applied to a realistic flight control problem. The resulting model is used to analyze both overall simulation effects and the effects of individual elements. The results show that, as compared to an ideal continuous simulation, the discrete simulation can result in significant performance and/or workload penalties.
Induction generator models in dynamic simulation tools
Knudsen, Hans; Akhmatov, Vladislav
1999-01-01
For AC network with large amount of induction generators (windmills) the paper demonstrates a significant discrepancy in the simulated voltage recovery after fault in weak networks when comparing dynamic and transient stability descriptions and the reasons of discrepancies are explained. It is fo......For AC network with large amount of induction generators (windmills) the paper demonstrates a significant discrepancy in the simulated voltage recovery after fault in weak networks when comparing dynamic and transient stability descriptions and the reasons of discrepancies are explained....... It is found to be possible to include a transient model in dynamic stability tools and, then, obtain correct results also in dynamic tools. The representation of the rotating system influences on the voltage recovery shape which is an important observation in case of windmills, where a heavy mill is connected...
Galaxy alignments: Theory, modelling and simulations
Kiessling, Alina; Joachimi, Benjamin; Kirk, Donnacha; Kitching, Thomas D; Leonard, Adrienne; Mandelbaum, Rachel; Schäfer, Björn Malte; Sifón, Cristóbal; Brown, Michael L; Rassat, Anais
2015-01-01
The shapes of galaxies are not randomly oriented on the sky. During the galaxy formation and evolution process, environment has a strong influence, as tidal gravitational fields in large-scale structure tend to align the shapes and angular momenta of nearby galaxies. Additionally, events such as galaxy mergers affect the relative alignments of galaxies throughout their history. These "intrinsic galaxy alignments" are known to exist, but are still poorly understood. This review will offer a pedagogical introduction to the current theories that describe intrinsic galaxy alignments, including the apparent difference in intrinsic alignment between early- and late-type galaxies and the latest efforts to model them analytically. It will then describe the ongoing efforts to simulate intrinsic alignments using both $N$-body and hydrodynamic simulations. Due to the relative youth of this field, there is still much to be done to understand intrinsic galaxy alignments and this review summarises the current state of the ...
A Simulation Model for Component Commonality
ZHU Xiao-chi; ZHANG Zi-gang
2002-01-01
Component commonality has been cited as a powerful approach for manufacturers to cope with increased component proliferation and to control inventory costs. To fully realize its potential benefits, one needs a clear understanding of its impacts on the system. In this paper, the feasibility of using a simulation model to provide a systematic perspective for manufacturing firms to implement a commonality strategy is demonstrated. Alternative commonality strategies including the stage of employing commonality and the allocation policies are simulated. Several interesting results on effects of commonality, allocation policies,and optimal solutions are obtained. We then summarize qualitative insights and managerial implications into the component commonality design and implementation, and inventory management in a general multi-stage assembly system.
Assumed PDF modeling in rocket combustor simulations
Lempke, M.; Gerlinger, P.; Aigner, M.
2013-03-01
In order to account for the interaction between turbulence and chemistry, a multivariate assumed PDF (Probability Density Function) approach is used to simulate a model rocket combustor with finite-rate chemistry. The reported test case is the PennState preburner combustor with a single shear coaxial injector. Experimental data for the wall heat flux is available for this configuration. Unsteady RANS (Reynolds-averaged Navier-Stokes) simulation results with and without the assumed PDF approach are analyzed and compared with the experimental data. Both calculations show a good agreement with the experimental wall heat flux data. Significant changes due to the utilization of the assumed PDF approach can be observed in the radicals, e. g., the OH mass fraction distribution, while the effect on the wall heat flux is insignificant.
Continuum damage modeling and simulation of hierarchical dental enamel
Ma, Songyun; Scheider, Ingo; Bargmann, Swantje
2016-05-01
Dental enamel exhibits high fracture toughness and stiffness due to a complex hierarchical and graded microstructure, optimally organized from nano- to macro-scale. In this study, a 3D representative volume element (RVE) model is adopted to study the deformation and damage behavior of the fibrous microstructure. A continuum damage mechanics model coupled to hyperelasticity is developed for modeling the initiation and evolution of damage in the mineral fibers as well as protein matrix. Moreover, debonding of the interface between mineral fiber and protein is captured by employing a cohesive zone model. The dependence of the failure mechanism on the aspect ratio of the mineral fibers is investigated. In addition, the effect of the interface strength on the damage behavior is studied with respect to geometric features of enamel. Further, the effect of an initial flaw on the overall mechanical properties is analyzed to understand the superior damage tolerance of dental enamel. The simulation results are validated by comparison to experimental data from micro-cantilever beam testing at two hierarchical levels. The transition of the failure mechanism at different hierarchical levels is also well reproduced in the simulations.
Traffic flow dynamics data, models and simulation
Treiber, Martin
2013-01-01
This textbook provides a comprehensive and instructive coverage of vehicular traffic flow dynamics and modeling. It makes this fascinating interdisciplinary topic, which to date was only documented in parts by specialized monographs, accessible to a broad readership. Numerous figures and problems with solutions help the reader to quickly understand and practice the presented concepts. This book is targeted at students of physics and traffic engineering and, more generally, also at students and professionals in computer science, mathematics, and interdisciplinary topics. It also offers material for project work in programming and simulation at college and university level. The main part, after presenting different categories of traffic data, is devoted to a mathematical description of the dynamics of traffic flow, covering macroscopic models which describe traffic in terms of density, as well as microscopic many-particle models in which each particle corresponds to a vehicle and its driver. Focus chapters on ...
Biomechanics trends in modeling and simulation
Ogden, Ray
2017-01-01
The book presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues. Seven well-known scientists working in that particular field discuss topics such as biomolecules, networks and cells as well as failure, multi-scale, agent-based, bio-chemo-mechanical and finite element models appropriate for computational analysis. Applications include arteries, the heart, vascular stents and valve implants as well as adipose, brain, collagenous and engineered tissues. The mechanics of the whole cell and sub-cellular components as well as the extracellular matrix structure and mechanotransduction are described. In particular, the formation and remodeling of stress fibers, cytoskeletal contractility, cell adhesion and the mechanical regulation of fibroblast migration in healing myocardial infarcts are discussed. The essential ingredients of continuum mechanics are provided. Constitutive models of fiber-reinforced materials with an emphasis on arterial walls ...
Hierarchical Boltzmann simulations and model error estimation
Torrilhon, Manuel; Sarna, Neeraj
2017-08-01
A hierarchical simulation approach for Boltzmann's equation should provide a single numerical framework in which a coarse representation can be used to compute gas flows as accurately and efficiently as in computational fluid dynamics, but a subsequent refinement allows to successively improve the result to the complete Boltzmann result. We use Hermite discretization, or moment equations, for the steady linearized Boltzmann equation for a proof-of-concept of such a framework. All representations of the hierarchy are rotationally invariant and the numerical method is formulated on fully unstructured triangular and quadrilateral meshes using a implicit discontinuous Galerkin formulation. We demonstrate the performance of the numerical method on model problems which in particular highlights the relevance of stability of boundary conditions on curved domains. The hierarchical nature of the method allows also to provide model error estimates by comparing subsequent representations. We present various model errors for a flow through a curved channel with obstacles.
Modelling and Simulation for Major Incidents
Eleonora Pacciani
2015-11-01
Full Text Available In recent years, there has been a rise in Major Incidents with big impact on the citizens health and the society. Without the possibility of conducting live experiments when it comes to physical and/or toxic trauma, only an accurate in silico reconstruction allows us to identify organizational solutions with the best possible chance of success, in correlation with the limitations on available resources (e.g. medical team, first responders, treatments, transports, and hospitals availability and with the variability of the characteristic of event (e.g. type of incident, severity of the event and type of lesions. Utilizing modelling and simulation techniques, a simplified mathematical model of physiological evolution for patients involved in physical and toxic trauma incident scenarios has been developed and implemented. The model formalizes the dynamics, operating standards and practices of medical response and the main emergency service in the chain of emergency management during a Major Incident.
Vertical eddy heat fluxes from model simulations
Stone, Peter H.; Yao, Mao-Sung
1991-01-01
Vertical eddy fluxes of heat are calculated from simulations with a variety of climate models, ranging from three-dimensional GCMs to a one-dimensional radiative-convective model. The models' total eddy flux in the lower troposphere is found to agree well with Hantel's analysis from observations, but in the mid and upper troposphere the models' values are systematically 30 percent to 50 percent smaller than Hantel's. The models nevertheless give very good results for the global temperature profile, and the reason for the discrepancy is unclear. The model results show that the manner in which the vertical eddy flux is carried is very sensitive to the parameterization of moist convection. When a moist adiabatic adjustment scheme with a critical value for the relative humidity of 100 percent is used, the vertical transports by large-scale eddies and small-scale convection on a global basis are equal: but when a penetrative convection scheme is used, the large-scale flux on a global basis is only about one-fifth to one-fourth the small-scale flux. Comparison of the model results with observations indicates that the results with the latter scheme are more realistic. However, even in this case, in mid and high latitudes the large and small-scale vertical eddy fluxes of heat are comparable in magnitude above the planetary boundary layer.
Heinrich events modeled in transient glacial simulations
Ziemen, Florian; Kapsch, Marie; Mikolajewicz, Uwe
2017-04-01
Heinrich events are among the most prominent events of climate variability recorded in proxies across the northern hemisphere. They are the archetype of ice sheet — climate interactions on millennial time scales. Nevertheless, the exact mechanisms that cause Heinrich events are still under debate, and their climatic consequences are far from being fully understood. We address open questions by studying Heinrich events in a coupled ice sheet model (ISM) atmosphere-ocean-vegetation general circulation model (AOVGCM) framework, where this variability occurs as part of the model generated internal variability. The framework consists of a northern hemisphere setup of the modified Parallel Ice Sheet Model (mPISM) coupled to the global AOVGCM ECHAM5/MPIOM/LPJ. The simulations were performed fully coupled and with transient orbital and greenhouse gas forcing. They span from several millennia before the last glacial maximum into the deglaciation. To make these long simulations feasible, the atmosphere is accelerated by a factor of 10 relative to the other model components using a periodical-synchronous coupling technique. To disentangle effects of the Heinrich events and the deglaciation, we focus on the events occurring before the deglaciation. The modeled Heinrich events show a peak ice discharge of about 0.05 Sv and raise the sea level by 2.3 m on average. The resulting surface water freshening reduces the Atlantic meridional overturning circulation and ocean heat release. The reduction in ocean heat release causes a sub-surface warming and decreases the air temperature and precipitation regionally and downstream into Eurasia. The surface elevation decrease of the ice sheet enhances moisture transport onto the ice sheet and thus increases precipitation over the Hudson Bay area, thereby accelerating the recovery after an event.
Modeling and Simulation. III. Simulation of a Model for Development of Visual Cortical Specificity.
1986-12-15
of parameter values. Experiment, model, and simulation 5’ The simulations we consider mimic, in form, classic deprivation experiments. Kittens are...second paper of the series (ref. 8) reviews the results of numerous experiments on the neuronal development of kitten visual cortex. We have...restricted to a very limited range of oriented contours (see citations in ref. 8). Kittens were raised, for example, viewing only horizontal or only vertical
An Agent-Based Monetary Production Simulation Model
Bruun, Charlotte
2006-01-01
An Agent-Based Simulation Model Programmed in Objective Borland Pascal. Program and source code is downloadable......An Agent-Based Simulation Model Programmed in Objective Borland Pascal. Program and source code is downloadable...
An Agent-Based Monetary Production Simulation Model
Bruun, Charlotte
2006-01-01
An Agent-Based Simulation Model Programmed in Objective Borland Pascal. Program and source code is downloadable......An Agent-Based Simulation Model Programmed in Objective Borland Pascal. Program and source code is downloadable...
The simulation model of planar electrochemical transducer
Zhevnenko, D. A.; Vergeles, S. S.; Krishtop, T. V.; Tereshonok, D. V.; Gornev, E. S.; Krishtop, V. G.
2016-12-01
Planar electrochemical systems are very perspective to build modern motion and pressure sensors. Planar microelectronic technology is successfully used for electrochemical transducer of motion parameters. These systems are characterized by an exceptionally high sensitivity towards mechanic exposure due to high rate of conversion of the mechanic signal to electric current. In this work, we have developed a mathematical model of this planar electrochemical system, which detects the mechanical signals. We simulate the processes of mass and charge transfer in planar electrochemical transducer and calculated its transfer function with different geometrical parameters of the system.
Agent-based modeling and simulation
Taylor, Simon
2014-01-01
Operational Research (OR) deals with the use of advanced analytical methods to support better decision-making. It is multidisciplinary with strong links to management science, decision science, computer science and many application areas such as engineering, manufacturing, commerce and healthcare. In the study of emergent behaviour in complex adaptive systems, Agent-based Modelling & Simulation (ABMS) is being used in many different domains such as healthcare, energy, evacuation, commerce, manufacturing and defense. This collection of articles presents a convenient introduction to ABMS with pa
Petroleum reservoir data for testing simulation models
Lloyd, J.M.; Harrison, W.
1980-09-01
This report consists of reservoir pressure and production data for 25 petroleum reservoirs. Included are 5 data sets for single-phase (liquid) reservoirs, 1 data set for a single-phase (liquid) reservoir with pressure maintenance, 13 data sets for two-phase (liquid/gas) reservoirs and 6 for two-phase reservoirs with pressure maintenance. Also given are ancillary data for each reservoir that could be of value in the development and validation of simulation models. A bibliography is included that lists the publications from which the data were obtained.
Schwinger model simulations with dynamical overlap fermions
Bietenholz, W; Volkholz, J
2007-01-01
We present simulation results for the 2-flavour Schwinger model with dynamical overlap fermions. In particular we apply the overlap hypercube operator at seven light fermion masses. In each case we collect sizable statistics in the topological sectors 0 and 1. Since the chiral condensate Sigma vanishes in the chiral limit, we observe densities for the microscopic Dirac spectrum, which have not been addressed yet by Random Matrix Theory (RMT). Nevertheless, by confronting the averages of the lowest eigenvalues in different topological sectors with chiral RMT in unitary ensemble we obtain -- for the very light fermion masses -- values for $\\Sigma$ that follow closely the analytical predictions in the continuum.
Schwinger model simulations with dynamical overlap fermions
Bietenholz, W. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Shcheredin, S. [Bielefeld Univ. (Germany). Fakultaet fuer Physik; Volkholz, J. [Humboldt-Universitaet, Berlin (Germany). Inst. fuer Physik
2007-11-15
We present simulation results for the 2-flavour Schwinger model with dynamical overlap fermions. In particular we apply the overlap hypercube operator at seven light fermion masses. In each case we collect sizable statistics in the topological sectors 0 and 1. Since the chiral condensate {sigma} vanishes in the chiral limit, we observe densities for the microscopic Dirac spectrum, which have not been addressed yet by Random Matrix Theory (RMT). Nevertheless, by confronting the averages of the lowest eigenvalues in different topological sectors with chiral RMT in unitary ensemble we obtain - for the very light fermion masses - values for {sigma} that follow closely the analytical predictions in the continuum. (orig.)
Induction generator models in dynamic simulation tools
Knudsen, Hans; Akhmatov, Vladislav
1999-01-01
. It is found to be possible to include a transient model in dynamic stability tools and, then, obtain correct results also in dynamic tools. The representation of the rotating system influences on the voltage recovery shape which is an important observation in case of windmills, where a heavy mill is connected......For AC network with large amount of induction generators (windmills) the paper demonstrates a significant discrepancy in the simulated voltage recovery after fault in weak networks when comparing dynamic and transient stability descriptions and the reasons of discrepancies are explained...
CASTOR detector Model, objectives and simulated performance
Angelis, Aris L S; Bartke, Jerzy; Bogolyubsky, M Yu; Chileev, K; Erine, S; Gladysz-Dziadus, E; Kharlov, Yu V; Kurepin, A B; Lobanov, M O; Maevskaya, A I; Mavromanolakis, G; Nicolis, N G; Panagiotou, A D; Sadovsky, S A; Wlodarczyk, Z
2001-01-01
We present a phenomenological model describing the formation and evolution of a Centauro fireball in the baryon-rich region in nucleus-nucleus interactions in the upper atmosphere and at the LHC. The small particle multiplicity and imbalance of electromagnetic and hadronic content characterizing a Centauro event and also the strongly penetrating particles (assumed to be strangelets) frequently accompanying them can be naturally explained. We describe the CASTOR calorimeter, a subdetector of the ALICE experiment dedicated to the search for Centauro in the very forward, baryon-rich region of central Pb+Pb collisions at the LHC. The basic characteristics and simulated performance of the calorimeter are presented. (22 refs).
CASTOR detector. Model, objectives and simulated performance
Angelis, A. L. S.; Mavromanolakis, G.; Panagiotou, A. D. [University of Athens, Nuclear and Particle Physics Division, Athens (Greece); Aslanoglou, X.; Nicolis, N. [Ioannina Univ., Ioannina (Greece). Dept. of Physics; Bartke, J.; Gladysz-Dziadus, E. [Institute of Nuclear Physics, Cracow (Poland); Lobanov, M.; Erine, S.; Kharlov, Y.V.; Bogolyubsky, M.Y. [Institute for High Energy Physics, Protvino (Russian Federation); Kurepin, A.B.; Chileev, K. [Institute for Nuclear Research, Moscow (Russian Federation); Wlodarczyk, Z. [Pedagogical University, Institute of Physics, Kielce (Poland)
2001-10-01
It is presented a phenomenological model describing the formation and evolution of a Centauro fireball in the baryon-rich region in nucleus-nucleus interactions in the upper atmosphere and at the LHC. The small particle multiplicity and imbalance of electromagnetic and hadronic content characterizing a Centauro event and also the strongly penetrating particles (assumed to be strangelets) frequently accompanying them can be naturally explained. It is described the CASTOR calorimeter, a sub detector of the ALICE experiment dedicated to the search for Centauro in the very forward, baryon-rich region of central Pb+Pb collisions at the LHC. The basic characteristics and simulated performance of the calorimeter are presented.
Modelling and simulations of controlled release fertilizer
Irfan, Sayed Ameenuddin; Razali, Radzuan; Shaari, Ku Zilati Ku; Mansor, Nurlidia
2016-11-01
The recent advancement in controlled release fertilizer has provided an alternative solution to the conventional urea, controlled release fertilizer has a good plant nutrient uptake they are environment friendly. To have an optimum plant intake of nutrients from controlled release fertilizer it is very essential to understand the release characteristics. A mathematical model is developed to predict the release characteristics from polymer coated granule. Numerical simulations are performed by varying the parameters radius of granule, soil water content and soil porosity to study their effect on fertilizer release. Understanding these parameters helps in the better design and improve the efficiency of controlled release fertilizer.
Monte Carlo Simulation of River Meander Modelling
Posner, A. J.; Duan, J. G.
2010-12-01
This study first compares the first order analytical solutions for flow field by Ikeda et. al. (1981) and Johanesson and Parker (1989b). Ikeda et. al.’s (1981) linear bank erosion model was implemented to predict the rate of bank erosion in which the bank erosion coefficient is treated as a stochastic variable that varies with physical properties of the bank (e.g. cohesiveness, stratigraphy, vegetation density). The developed model was used to predict the evolution of meandering planforms. Then, the modeling results were analyzed and compared to the observed data. Since the migration of meandering channel consists of downstream translation, lateral expansion, and downstream or upstream rotations. Several measures are formulated in order to determine which of the resulting planform is closest to the experimental measured one. Results from the deterministic model highly depend on the calibrated erosion coefficient. Since field measurements are always limited, the stochastic model yielded more realistic predictions of meandering planform evolutions. Due to the random nature of bank erosion coefficient, the meandering planform evolution is a stochastic process that can only be accurately predicted by a stochastic model. Quasi-2D Ikeda (1989) flow solution with Monte Carlo Simulation of Bank Erosion Coefficient.
Axisymmetric Vortex Simulations with Various Turbulence Models
Brian Howard Fiedler
2010-10-01
Full Text Available The CFD code FLUENT^{TM} has been applied to a vortex within an updraft above a frictional lower boundary. The sensitivity of vortex intensity and structure to the choice of turbulent model is explored. A high Reynolds number of 10^{8} is employed to make the investigation relevant to the atmospheric vortex known as a tornado. The simulations are axisymmetric and are integrated forward in time to equilibrium. In a variety of turbulence models tested, the Reynolds Stress Model allows for the greatest intensification of the vortex, with the azimuthal wind speed near the surface being 2.4 times the speed of the updraft, consistent with the destructive nature of tornadoes. The Standard k-e Model, which is simpler than the Reynolds Stress Model but still more detailed than what is commonly available in numerical weather prediction models, produces an azimuthal wind speed near the surface of at most 0.6 times the updraft speed.
Simulation model for port shunting yards
Rusca, A.; Popa, M.; Rosca, E.; Rosca, M.; Dragu, V.; Rusca, F.
2016-08-01
Sea ports are important nodes in the supply chain, joining two high capacity transport modes: rail and maritime transport. The huge cargo flows transiting port requires high capacity construction and installation such as berths, large capacity cranes, respectively shunting yards. However, the port shunting yards specificity raises several problems such as: limited access since these are terminus stations for rail network, the in-output of large transit flows of cargo relatively to the scarcity of the departure/arrival of a ship, as well as limited land availability for implementing solutions to serve these flows. It is necessary to identify technological solutions that lead to an answer to these problems. The paper proposed a simulation model developed with ARENA computer simulation software suitable for shunting yards which serve sea ports with access to the rail network. Are investigates the principal aspects of shunting yards and adequate measures to increase their transit capacity. The operation capacity for shunting yards sub-system is assessed taking in consideration the required operating standards and the measure of performance (e.g. waiting time for freight wagons, number of railway line in station, storage area, etc.) of the railway station are computed. The conclusion and results, drawn from simulation, help transports and logistics specialists to test the proposals for improving the port management.
The mathematical model of a LUNG simulator
František Šolc
2014-12-01
Full Text Available The paper discusses the design, modelling, implementation and testing of a specific LUNG simulator,. The described research was performed as a part of the project AlveoPic – Advanced Lung Research for Veterinary Medicine of Particles for Inhalation. The simulator was designed to establish a combined study programme comprising Biomedical Engineering Sciences (FEEC BUT and Healthcare and Rehabilitation Technology (FH Technikum Wien. The simulator is supposed to be an advanced laboratory equipment which should enhance the standard of the existing research activities within the above-mentioned study programs to the required level. Thus, the proposed paper introduces significant technical equipment for the laboratory education of students at both FH Technikum Wien and the Faculty of Electrical Engineering and Communication, Brno University of Technology. The apparatuses described here will be also used to support cooperative research activities. In the given context, the authors specify certain technical solutions and parameters related to artificial lungs, present the electrical equipment of the system, and point out the results of the PC-based measurement and control.
Three-dimensional conceptual model for service-oriented simulation
Wen-guang WANG; Wei-ping WANG; Justyna ZANDER; Yi-fan ZHU
2009-01-01
In this letter, we propose a novel three-dimensional conceptual model for an emerging service-oriented simulation paradigm. The model can be used as a guideline or an analytic means to find the potential and possible future directions of the current simulation frameworks, In particular, the model inspects the crossover between the disciplines of modeling and simulation,service-orientation, and software/systems engineering. Finally, two specific simulation frameworks are studied as examples.
Three-dimensional conceptual model for service-oriented simulation
Wang, Wenguang; Zander, Justyna; Zhu, Yifan; 10.1631/jzus.A0920258
2009-01-01
In this letter, we propose a novel three-dimensional conceptual model for an emerging service-oriented simulation paradigm. The model can be used as a guideline or an analytic means to find the potential and possible future directions of the current simulation frameworks. In particular, the model inspects the crossover between the disciplines of modeling and simulation, service-orientation, and software/systems engineering. Finally, two specific simulation frameworks are studied as examples.
Numerical Simulations of Separated Flows Using Wall-Modeled LES
Vane, Zachary; Ortega, Jason; Salari, Kambiz
2014-11-01
Calculations using an unstructured, wall-modeled large eddy simulation (WMLES) solver are performed for several high Reynolds number test cases of interest. While the equilibrium formulation of this wall-model (Bodart, Larsson & Moin, AIAA 2013-2724) has proven to be accurate for steady, attached boundary layers, its application to non-equilibrium or highly three-dimensional problems has yet to be fully explored. A series of turbulent flows that exhibit boundary layer separation due to the geometries involved in each test case are considered. First, spanwise-periodic simulations for the flow over periodic hills are performed at multiple Reynolds numbers. Next, calculations involving separation caused by three-dimensional bodies are used to generate more complex flow fields and to evaluate the accuracy of the WMLES in the separated wake region downstream. The performance of the WMLES is quantified through comparisons with existing numerical and experimental data sets. The effects of grid resolution and variations in several wall-model parameters are also investigated to determine their influence on the overall calculation.
Global Solar Dynamo Models: Simulations and Predictions
Mausumi Dikpati; Peter A. Gilman
2008-03-01
Flux-transport type solar dynamos have achieved considerable success in correctly simulating many solar cycle features, and are now being used for prediction of solar cycle timing and amplitude.We first define flux-transport dynamos and demonstrate how they work. The essential added ingredient in this class of models is meridional circulation, which governs the dynamo period and also plays a crucial role in determining the Sun’s memory about its past magnetic fields.We show that flux-transport dynamo models can explain many key features of solar cycles. Then we show that a predictive tool can be built from this class of dynamo that can be used to predict mean solar cycle features by assimilating magnetic field data from previous cycles.
Design and Simulation of Toroidal Twister Model
TIAN Huifang; LIN Xizhen; ZENG Qinqin
2006-01-01
Toroidal composite vessel winded with fiber is a new kind of structural pressure vessels, which not only has high structure efficiency of compound materials pressure vessel, good security and so on, but also has special shape and the property of utilizing toroidal space, and the prospect of the application of toroidal composite vessel winded with fiber is extremely broad. By introducing parameters establishment of toroidal vessel and elaborating the principle of filament winding for toroidal vessel, the design model of filament winding machine for toroidal vessel has been introduced, and the design model has been dynamically simulated by the software of ADAMS, which will give more referrence for the design of real toroidal vessel twister.
VISION: Verifiable Fuel Cycle Simulation Model
Jacob J. Jacobson; Abdellatif M. Yacout; Gretchen E. Matthern; Steven J. Piet; David E. Shropshire
2009-04-01
The nuclear fuel cycle is a very complex system that includes considerable dynamic complexity as well as detail complexity. In the nuclear power realm, there are experts and considerable research and development in nuclear fuel development, separations technology, reactor physics and waste management. What is lacking is an overall understanding of the entire nuclear fuel cycle and how the deployment of new fuel cycle technologies affects the overall performance of the fuel cycle. The Advanced Fuel Cycle Initiative’s systems analysis group is developing a dynamic simulation model, VISION, to capture the relationships, timing and delays in and among the fuel cycle components to help develop an understanding of how the overall fuel cycle works and can transition as technologies are changed. This paper is an overview of the philosophy and development strategy behind VISION. The paper includes some descriptions of the model and some examples of how to use VISION.
Modeling and visual simulation of Microalgae photobioreactor
Zhao, Ming; Hou, Dapeng; Hu, Dawei
Microalgae is a kind of nutritious and high photosynthetic efficiency autotrophic plant, which is widely distributed in the land and the sea. It can be extensively used in medicine, food, aerospace, biotechnology, environmental protection and other fields. Photobioreactor which is important equipment is mainly used to cultivate massive and high-density microalgae. In this paper, based on the mathematical model of microalgae which grew under different light intensity, three-dimensional visualization model was built and implemented in 3ds max, Virtools and some other three dimensional software. Microalgae is photosynthetic organism, it can efficiently produce oxygen and absorb carbon dioxide. The goal of the visual simulation is to display its change and impacting on oxygen and carbon dioxide intuitively. In this paper, different temperatures and light intensities were selected to control the photobioreactor, and dynamic change of microalgal biomass, Oxygen and carbon dioxide was observed with the aim of providing visualization support for microalgal and photobioreactor research.
A rainfall simulation model for agricultural development in Bangladesh
M. Sayedur Rahman
2000-01-01
Full Text Available A rainfall simulation model based on a first-order Markov chain has been developed to simulate the annual variation in rainfall amount that is observed in Bangladesh. The model has been tested in the Barind Tract of Bangladesh. Few significant differences were found between the actual and simulated seasonal, annual and average monthly. The distribution of number of success is asymptotic normal distribution. When actual and simulated daily rainfall data were used to drive a crop simulation model, there was no significant difference of rice yield response. The results suggest that the rainfall simulation model perform adequately for many applications.
Toy Models for Galaxy Formation versus Simulations
Dekel, A; Tweed, D; Cacciato, M; Ceverino, D; Primack, J R
2013-01-01
We describe simple useful toy models for key processes of galaxy formation in its most active phase, at z > 1, and test the approximate expressions against the typical behaviour in a suite of high-resolution hydro-cosmological simulations of massive galaxies at z = 4-1. We address in particular the evolution of (a) the total mass inflow rate from the cosmic web into galactic haloes based on the EPS approximation, (b) the penetration of baryonic streams into the inner galaxy, (c) the disc size, (d) the implied steady-state gas content and star-formation rate (SFR) in the galaxy subject to mass conservation and a universal star-formation law, (e) the inflow rate within the disc to a central bulge and black hole as derived using energy conservation and self-regulated Q ~ 1 violent disc instability (VDI), and (f) the implied steady state in the disc and bulge. The toy models provide useful approximations for the behaviour of the simulated galaxies. We find that (a) the inflow rate is proportional to mass and to (...
Modelling and simulation of multitechnological machine systems
Holopainen, T. (ed.) [VTT Manufacturing Technology, Espoo (Finland)
2001-07-01
The Smart Machines and Systems 2010 (SMART) technology programme 1997-2000 aimed at supporting the machine and electromechanical industries in incorporating the modern technology into their products and processes. The public research projects in this programme were planned to accumulate the latest research results and transfer them for the benefit of industrial product development. The major research topic in the SMART programme was called Modelling and Simulation of Multitechnological Mechatronic Systems. The behaviour of modern machine systems and subsystems addresses many different types of physical phenomena and their mutual interactions: mechanical behaviour of structures, electromagnetic effects, hydraulics, vibrations and acoustics etc. together with associated control systems and software. The actual research was carried out in three separate projects called Modelling and Simulation of Mechtronic Machine Systems for Product Development and Condition Monitoring Purposes (MASI), Virtual Testing of Hydraulically Driven Machines (HYSI), and Control of Low Frequency Vibration of a Mobile Machine (AKSUS). This publication contains the papers presented at the final seminar of these three research projects, held on November 30th at Otaniemi Espoo. (orig.)
Towards Modelling and Simulation of Crowded Environments in Cell Biology
Bittig, Arne T.; Jeschke, Matthias; Uhrmacher, Adelinde M.
2010-09-01
In modelling and simulation of cell biological processes, spatial homogeneity in the distribution of components is a common but not always valid assumption. Spatial simulation methods differ in computational effort and accuracy, and usually rely on tool-specific input formats for model specification. A clear separation between modelling and simulation allows a declarative model specification thereby facilitating reuse of models and exploiting different simulators. We outline a modelling formalism covering both stochastic spatial simulation at the population level and simulation of individual entities moving in continuous space as well as the combination thereof. A multi-level spatial simulator is presented that combines populations of small particles simulated according to the Next Subvolume Method with individually represented large particles following Brownian motion. This approach entails several challenges that need to be overcome, but nicely balances between calculation effort and required levels of detail.
Modeling and simulation of cascading contingencies
Zhang, Jianfeng
This dissertation proposes a new approach to model and study cascading contingencies in large power systems. The most important contribution of the work involves the development and validation of a heuristic analytic model to assess the likelihood of cascading contingencies, and the development and validation of a uniform search strategy. We model the probability of cascading contingencies as a function of power flow and power flow changes. Utilizing logistic regression, the proposed model is calibrated using real industry data. This dissertation analyzes random search strategies for Monte Carlo simulations and proposes a new uniform search strategy based on the Metropolis-Hastings Algorithm. The proposed search strategy is capable of selecting the most significant cascading contingencies, and it is capable of constructing an unbiased estimator to provide a measure of system security. This dissertation makes it possible to reasonably quantify system security and justify security operations when economic concerns conflict with reliability concerns in the new competitive power market environment. It can also provide guidance to system operators about actions that may be taken to reduce the risk of major system blackouts. Various applications can be developed to take advantage of the quantitative security measures provided in this dissertation.
The fractional-nonlinear robotic manipulator: Modeling and dynamic simulations
David, S. A.; Balthazar, J. M.; Julio, B. H. S.; Oliveira, C.
2012-11-01
In this paper, we applied the Riemann-Liouville approach and the fractional Euler-Lagrange equations in order to obtain the fractional-order nonlinear dynamics equations of a two link robotic manipulator. The aformentioned equations have been simulated for several cases involving: integer and non-integer order analysis, with and without external forcing acting and some different initial conditions. The fractional nonlinear governing equations of motion are coupled and the time evolution of the angular positions and the phase diagrams have been plotted to visualize the effect of fractional order approach. The new contribution of this work arises from the fact that the dynamics equations of a two link robotic manipulator have been modeled with the fractional Euler-Lagrange dynamics approach. The results reveal that the fractional-nonlinear robotic manipulator can exhibit different and curious behavior from those obtained with the standard dynamical system and can be useful for a better understanding and control of such nonlinear systems.
Nonlinear distortion in wireless systems modeling and simulation with Matlab
Gharaibeh, Khaled M
2011-01-01
This book covers the principles of modeling and simulation of nonlinear distortion in wireless communication systems with MATLAB simulations and techniques In this book, the author describes the principles of modeling and simulation of nonlinear distortion in single and multichannel wireless communication systems using both deterministic and stochastic signals. Models and simulation methods of nonlinear amplifiers explain in detail how to analyze and evaluate the performance of data communication links under nonlinear amplification. The book addresses the analysis of nonlinear systems
AISIM (Automated Interactive Simulation Modeling System) VAX Version Training Manual.
1985-02-01
AD-Ri6t 436 AISIM (RUTOMATED INTERACTIVE SIMULATION MODELING 1/2 SYSTEM) VAX VERSION TRAI (U) HUGHES AIRCRAFT CO FULLERTON CA GROUND SYSTEMS GROUP S...Continue on reverse if necessary and Identify by block number) THIS DOCUMENT IS THE TRAINING MANUAL FOR THE AUTOMATED INTERACTIVE SIMULATION MODELING SYSTEM...form. Page 85 . . . . . . . . APPENDIX B SIMULATION REPORT FOR WORKING EXAMPLE Pa jPage.8 7AD-Ai6i 46 ISIM (AUTOMATED INTERACTIVE SIMULATION MODELING 2
Tecnomatix Plant Simulation modeling and programming by means of examples
Bangsow, Steffen
2015-01-01
This book systematically introduces the development of simulation models as well as the implementation and evaluation of simulation experiments with Tecnomatix Plant Simulation. It deals with all users of Plant Simulation, who have more complex tasks to handle. It also looks for an easy entry into the program. Particular attention has been paid to introduce the simulation flow language SimTalk and its use in various areas of the simulation. The author demonstrates with over 200 examples how to combine the blocks for simulation models and how to deal with SimTalk for complex control and analys
Comparing Productivity Simulated with Inventory Data Using Different Modelling Technologies
Klopf, M.; Pietsch, S. A.; Hasenauer, H.
2009-04-01
The Lime Stone National Park in Austria was established in 1997 to protect sensible lime stone soils from degradation due to heavy forest management. Since 1997 the management activities were successively reduced and standing volume and coarse woody debris (CWD) increased and degraded soils began to recover. One option to study the rehabilitation process towards natural virgin forest state is the use of modelling technology. In this study we will test two different modelling approaches for their applicability to Lime Stone National Park. We will compare standing tree volume simulated resulting from (i) the individual tree growth model MOSES, and (ii) the species and management sensitive adaptation of the biogeochemical-mechanistic model Biome-BGC. The results from the two models are compared with filed observations form repeated permanent forest inventory plots of the Lime Stone National Park in Austria. The simulated CWD predictions of the BGC-model were compared with dead wood measurements (standing and lying dead wood) recorded at the permanent inventory plots. The inventory was established between 1994 and 1996 and remeasured from 2004 to 2005. For this analysis 40 plots of this inventory were selected which comprise the required dead wood components and are dominated by a single tree species. First we used the distance dependant individual tree growth model MOSES to derive the standing timber and the amount of mortality per hectare. MOSES is initialized with the inventory data at plot establishment and each sampling plot is treated as forest stand. The Biome-BGC is a process based biogeochemical model with extensions for Austrian tree species, a self initialization and a forest management tool. The initialization for the actual simulations with the BGC model was done as follows: We first used spin up runs to derive a balanced forest vegetation, similar to an undisturbed forest. Next we considered the management history of the past centuries (heavy clear cuts
Modeling human response errors in synthetic flight simulator domain
Ntuen, Celestine A.
1992-01-01
This paper presents a control theoretic approach to modeling human response errors (HRE) in the flight simulation domain. The human pilot is modeled as a supervisor of a highly automated system. The synthesis uses the theory of optimal control pilot modeling for integrating the pilot's observation error and the error due to the simulation model (experimental error). Methods for solving the HRE problem are suggested. Experimental verification of the models will be tested in a flight quality handling simulation.
Cognitive Modeling for Agent-Based Simulation of Child Maltreatment
Hu, Xiaolin; Puddy, Richard
This paper extends previous work to develop cognitive modeling for agent-based simulation of child maltreatment (CM). The developed model is inspired from parental efficacy, parenting stress, and the theory of planned behavior. It provides an explanatory, process-oriented model of CM and incorporates causality relationship and feedback loops from different factors in the social ecology in order for simulating the dynamics of CM. We describe the model and present simulation results to demonstrate the features of this model.
LADEE Satellite Modeling and Simulation Development
Adams, Michael; Cannon, Howard; Frost, Chad
2011-01-01
As human activity on and around the Moon increases, so does the likelihood that our actions will have an impact on its atmosphere. The Lunar Atmosphere and Dust Environment Explorer (LADEE), a NASA satellite scheduled to launch in 2013, will orbit the Moon collecting composition, density, and time variability data to characterize the current state of the lunar atmosphere. LADEE will also test the concept of the "Modular Common Bus" spacecraft architecture, an effort to reduce both development time and cost by designing reusable, modular components for use in multiple missions with similar requirements. An important aspect of this design strategy is to both simulate the spacecraft and develop the flight code in Simulink, a block diagram-style programming language that allows easy algorithm visualization and performance testing. Before flight code can be tested, however, a realistic simulation of the satellite and its dynamics must be generated and validated. This includes all of the satellite control system components such as actuators used for force and torque generation and sensors used for inertial orientation reference. My primary responsibilities have included designing, integrating, and testing models for the LADEE thrusters, reaction wheels, star trackers, and rate gyroscopes.
Modeling and simulation of axisymmetric stagnation flames
Sone, Kazuo
Laminar flame modeling is an important element in turbulent combustion research. The accuracy of a turbulent combustion model is highly dependent upon our understanding of laminar flames and their behavior in many situations. How much we understand combustion can only be measured by how well the model describes and predicts combustion phenomena. One of the most commonly used methane combustion models is GRI-Mech 3.0. However, how well the model describes the reacting flow phenomena is still uncertain even after many attempts to validate the model or quantify uncertainties. In the present study, the behavior of laminar flames under different aerodynamic and thermodynamic conditions is studied numerically in a stagnation-flow configuration. In order to make such a numerical study possible, the spectral element method is reformulated to accommodate the large density variations in methane reacting flows. In addition, a new axisymmetric basis function set for the spectral element method that satisfies the correct behavior near the axis is developed, and efficient integration techniques are developed to accurately model axisymmetric reacting flow within a reasonable amount of computational time. The numerical method is implemented using an object-oriented programming technique, and the resulting computer program is verified with several different verification methods. The present study then shows variances with the commonly used GRI-Mech 3.0 chemical kinetics model through a direct simulation of laboratory flames that allows direct comparison to experimental data. It is shown that the methane combustion model based on GRI-Mech 3.0 works well for methane-air mixtures near stoichiometry. However, GRI-Mech 3.0 leads to an overprediction of laminar flame speed for lean mixtures and an underprediction for rich mixtures. This result is slightly different from conclusion drawn in previous work, in which experimental data are compared with a one-dimensional numerical solutions
Modeling and simulation technology readiness levels.
Clay, Robert L.; Shneider, Max S.; Marburger, S. J.; Trucano, Timothy Guy
2006-01-01
This report summarizes the results of an effort to establish a framework for assigning and communicating technology readiness levels (TRLs) for the modeling and simulation (ModSim) capabilities at Sandia National Laboratories. This effort was undertaken as a special assignment for the Weapon Simulation and Computing (WSC) program office led by Art Hale, and lasted from January to September 2006. This report summarizes the results, conclusions, and recommendations, and is intended to help guide the program office in their decisions about the future direction of this work. The work was broken out into several distinct phases, starting with establishing the scope and definition of the assignment. These are characterized in a set of key assertions provided in the body of this report. Fundamentally, the assignment involved establishing an intellectual framework for TRL assignments to Sandia's modeling and simulation capabilities, including the development and testing of a process to conduct the assignments. To that end, we proposed a methodology for both assigning and understanding the TRLs, and outlined some of the restrictions that need to be placed on this process and the expected use of the result. One of the first assumptions we overturned was the notion of a ''static'' TRL--rather we concluded that problem context was essential in any TRL assignment, and that leads to dynamic results (i.e., a ModSim tool's readiness level depends on how it is used, and by whom). While we leveraged the classic TRL results from NASA, DoD, and Sandia's NW program, we came up with a substantially revised version of the TRL definitions, maintaining consistency with the classic level definitions and the Predictive Capability Maturity Model (PCMM) approach. In fact, we substantially leveraged the foundation the PCMM team provided, and augmented that as needed. Given the modeling and simulation TRL definitions and our proposed assignment methodology, we
Modeling and simulation of surface roughness
Patrikar, Rajendra M
2004-04-30
With the technology advancement, electronic devices are miniaturized at every development node. Physical parameters such as microscopic roughness are affecting these devices because surface to volume ratio is increasing rapidly. On all the real surfaces microscopic roughness appears, which affects many electronic properties of the material, which in turn decides the yield and reliability of the devices. Different type of parameters and simulation methods are used to describe the surface roughness. Classically surface roughness was modeled by methods such as power series and Fast Fourier Transform (FFT). Limitations of this methods lead to use the concept of self-similar fractals to model the rough surface through Mandelbrot-Weierstrass function. It is difficult to express surface roughness as a function of process parameters in the form of analytical functions. Method based on neural networks has been used to model these surfaces to map the process parameters to roughness parameters. Finally, change in electrical parameters such as capacitance, resistance and noise due to surface roughness has been computed by numerical methods.
Aminoglycoside nephrotoxicity: modeling, simulation, and control.
Rougier, Florent; Claude, Daniel; Maurin, Michel; Sedoglavic, Alexandre; Ducher, Michel; Corvaisier, Stéphane; Jelliffe, Roger; Maire, Pascal
2003-03-01
The main constraints on the administration of aminoglycosides are the risks of nephrotoxicity and ototoxicity, which can lead to acute, renal, vestibular, and auditory toxicities. In the present study we focused on nephrotoxicity. No reliable predictor of nephrotoxicity has been found to date. We have developed a deterministic model which describes the pharmacokinetic behavior of aminoglycosides (with a two-compartment model), the kinetics of aminoglycoside accumulation in the renal cortex, the effects of aminoglycosides on renal cells, the resulting effects on renal function by tubuloglomerular feedback, and the resulting effects on serum creatinine concentrations. The pharmacokinetic parameter values were estimated by use of the NPEM program. The estimated pharmacodynamic parameter values were obtained after minimization of the least-squares objective function between the measured and the calculated serum creatinine concentrations. A simulation program assessed the influences of the dosage regimens on the occurrence of nephrotoxicity. We have also demonstrated the relevancy of modeling of the circadian rhythm of the renal function. We have shown the ability of the model to fit with 49 observed serum creatinine concentrations for a group of eight patients treated for endocarditis by comparison with 49 calculated serum creatinine concentrations (r(2) = 0.988; P < 0.001). We have found that for the same daily dose, the nephrotoxicity observed with a thrice-daily administration schedule appears more rapidly, induces a greater decrease in renal function, and is more prolonged than those that occur with less frequent administration schedules (for example, once-daily administration). Moreover, for once-daily administration, we have demonstrated that the time of day of administration can influence the incidence of aminoglycoside nephrotoxicity. The lowest level of nephrotoxicity was observed when aminoglycosides were administered at 1:30 p.m. Clinical application of this
Cokonis, T. J.
The papers presented in this volume provide examples of the impact of computers on present engineering practice and indicate some future trends in computer-aided design, manufacturing, and simulation. Topics discussed include computer-aided design of turbine cycle configuration, managing and development of engineering computer systems, computer-aided manufacturing with robots in the automotive industry, and computer-aided design/analysis techniques of composite materials in the cure phase. Papers are also presented on computer simulation of vehicular propulsion systems, the performance of a hydraulic system simulator in a CAD environment, and computer simulation of hovercraft heave dynamics and control.
The modeling of miniature UAV flight visualization simulation platform
Li, Dong-hui; Li, Xin; Yang, Le-le; Li, Xiong
2015-12-01
This paper combines virtual technology with visualization visual simulation theory, construct the framework of visual simulation platform, apply open source software FlightGear simulator combined with GoogleEarth design a small UAV flight visual simulation platform. Using software AC3D to build 3D models of aircraft and complete the model loading based on XML configuration, the design and simulation of visualization modeling visual platform is presented. By using model-driven and data transforming in FlightGear , the design of data transmission module is realized based on Visual Studio 2010 development platform. Finally combined with GoogleEarth it can achieve the tracking and display.
Shuttle operations simulation model programmers'/users' manual
Porter, D. G.
1972-01-01
The prospective user of the shuttle operations simulation (SOS) model is given sufficient information to enable him to perform simulation studies of the space shuttle launch-to-launch operations cycle. The procedures used for modifying the SOS model to meet user requirements are described. The various control card sequences required to execute the SOS model are given. The report is written for users with varying computer simulation experience. A description of the components of the SOS model is included that presents both an explanation of the logic involved in the simulation of the shuttle operations cycle and a description of the routines used to support the actual simulation.
Discrete Element Simulation of Asphalt Mastics Based on Burgers Model
LIU Yu; FENG Shi-rong; HU Xia-guang
2007-01-01
In order to investigate the viscoelastic performance of asphalt mastics, a micro-mechanical model for asphalt mastics was built by applying Burgers model to discrete element simulation and constructing Burgers contact model. Then the numerical simulation of creep tests was conducted, and results from the simulation were compared with the analytical solution for Burgers model. The comparision snowed that the two results agreed well with each other, suggesting that discrete element model based on Burgers model could be employed in the numerical simulation for asphalt mastics.
A Geostationary Earth Orbit Satellite Model Using Easy Java Simulation
Wee, Loo Kang; Goh, Giam Hwee
2013-01-01
We develop an Easy Java Simulation (EJS) model for students to visualize geostationary orbits near Earth, modelled using a Java 3D implementation of the EJS 3D library. The simplified physics model is described and simulated using a simple constant angular velocity equation. We discuss four computer model design ideas: (1) a simple and realistic…
Knowledge-based modeling of discrete-event simulation systems
H. de Swaan Arons
1999-01-01
textabstractModeling a simulation system requires a great deal of customization. At first sight no system seems to resemble exactly another system and every time a new model has to be designed the modeler has to start from scratch. The present simulation languages provide the modeler with powerful
Knowledge-based modeling of discrete-event simulation systems
H. de Swaan Arons
1999-01-01
textabstractModeling a simulation system requires a great deal of customization. At first sight no system seems to resemble exactly another system and every time a new model has to be designed the modeler has to start from scratch. The present simulation languages provide the modeler with powerful t
A Geostationary Earth Orbit Satellite Model Using Easy Java Simulation
Wee, Loo Kang; Goh, Giam Hwee
2013-01-01
We develop an Easy Java Simulation (EJS) model for students to visualize geostationary orbits near Earth, modelled using a Java 3D implementation of the EJS 3D library. The simplified physics model is described and simulated using a simple constant angular velocity equation. We discuss four computer model design ideas: (1) a simple and realistic…
Gustafsson, Leif; Sternad, Mikael
2007-10-01
Population models concern collections of discrete entities such as atoms, cells, humans, animals, etc., where the focus is on the number of entities in a population. Because of the complexity of such models, simulation is usually needed to reproduce their complete dynamic and stochastic behaviour. Two main types of simulation models are used for different purposes, namely micro-simulation models, where each individual is described with its particular attributes and behaviour, and macro-simulation models based on stochastic differential equations, where the population is described in aggregated terms by the number of individuals in different states. Consistency between micro- and macro-models is a crucial but often neglected aspect. This paper demonstrates how the Poisson Simulation technique can be used to produce a population macro-model consistent with the corresponding micro-model. This is accomplished by defining Poisson Simulation in strictly mathematical terms as a series of Poisson processes that generate sequences of Poisson distributions with dynamically varying parameters. The method can be applied to any population model. It provides the unique stochastic and dynamic macro-model consistent with a correct micro-model. The paper also presents a general macro form for stochastic and dynamic population models. In an appendix Poisson Simulation is compared with Markov Simulation showing a number of advantages. Especially aggregation into state variables and aggregation of many events per time-step makes Poisson Simulation orders of magnitude faster than Markov Simulation. Furthermore, you can build and execute much larger and more complicated models with Poisson Simulation than is possible with the Markov approach.
Modeling and Simulation at Tidewater Community College
Summers, Michael
2008-01-01
Investment of $1.5 million in medical simulation technology. Integration of medical simulation activities into the curriculum. Support from TCC leadership. Individual and team activities. Skill development and critical thinking/problem solving skills.
Model simulations of rainfall over southern Africa and its eastern ...
2016-01-01
Jan 1, 2016 ... 2015). Two different types of CCAM simulations are ana- lysed here. Firstly, an ...... Sweden: observation versus model simulation. Tellus A 63 http:// ... for Atmospheric Sciences, September 2011, Hartebeeshoek. NESBITT SW ...
Lattice Boltzmann modeling of directional wetting: Comparing simulations to experiments
Jansen, H.P.; Sotthewes, K.; Swigchem, van J.; Zandvliet, H.J.W.; Kooij, E.S.
2013-01-01
Lattice Boltzmann Modeling (LBM) simulations were performed on the dynamic behavior of liquid droplets on chemically striped patterned surfaces, ultimately with the aim to develop a predictive tool enabling reliable design of future experiments. The simulations accurately mimic experimental results,
An educational model for ensemble streamflow simulation and uncertainty analysis
AghaKouchak, A; Nakhjiri, N; Habib, E
2013-01-01
...) are interconnected. The educational toolbox includes a MATLAB Graphical User Interface (GUI) and an ensemble simulation scheme that can be used for teaching uncertainty analysis, parameter estimation, ensemble simulation and model sensitivity...
Simulation and Modeling Application in Agricultural Mechanization
R. M. Hudzari
2012-01-01
Full Text Available This experiment was conducted to determine the equations relating the Hue digital values of the fruits surface of the oil palm with maturity stage of the fruit in plantation. The FFB images were zoomed and captured using Nikon digital camera, and the calculation of Hue was determined using the highest frequency of the value for R, G, and B color components from histogram analysis software. New procedure in monitoring the image pixel value for oil palm fruit color surface in real-time growth maturity was developed. The estimation of day harvesting prediction was calculated based on developed model of relationships for Hue values with mesocarp oil content. The simulation model is regressed and predicts the day of harvesting or a number of days before harvest of FFB. The result from experimenting on mesocarp oil content can be used for real-time oil content determination of MPOB color meter. The graph to determine the day of harvesting the FFB was presented in this research. The oil was found to start developing in mesocarp fruit at 65 days before fruit at ripe maturity stage of 75% oil to dry mesocarp.
Modelling toolkit for simulation of maglev devices
Peña-Roche, J.; Badía-Majós, A.
2017-01-01
A stand-alone App1 has been developed, focused on obtaining information about relevant engineering properties of magnetic levitation systems. Our modelling toolkit provides real time simulations of 2D magneto-mechanical quantities for superconductor (SC)/permanent magnet structures. The source code is open and may be customised for a variety of configurations. Ultimately, it relies on the variational statement of the critical state model for the superconducting component and has been verified against experimental data for YBaCuO/NdFeB assemblies. On a quantitative basis, the values of the arising forces, induced superconducting currents, as well as a plot of the magnetic field lines are displayed upon selection of an arbitrary trajectory of the magnet in the vicinity of the SC. The stability issues related to the cooling process, as well as the maximum attainable forces for a given material and geometry are immediately observed. Due to the complexity of the problem, a strategy based on cluster computing, database compression, and real-time post-processing on the device has been implemented.
Simulation Models for Socioeconomic Inequalities in Health: A Systematic Review
Niko Speybroeck
2013-11-01
Full Text Available Background: The emergence and evolution of socioeconomic inequalities in health involves multiple factors interacting with each other at different levels. Simulation models are suitable for studying such complex and dynamic systems and have the ability to test the impact of policy interventions in silico. Objective: To explore how simulation models were used in the field of socioeconomic inequalities in health. Methods: An electronic search of studies assessing socioeconomic inequalities in health using a simulation model was conducted. Characteristics of the simulation models were extracted and distinct simulation approaches were identified. As an illustration, a simple agent-based model of the emergence of socioeconomic differences in alcohol abuse was developed. Results: We found 61 studies published between 1989 and 2013. Ten different simulation approaches were identified. The agent-based model illustration showed that multilevel, reciprocal and indirect effects of social determinants on health can be modeled flexibly. Discussion and Conclusions: Based on the review, we discuss the utility of using simulation models for studying health inequalities, and refer to good modeling practices for developing such models. The review and the simulation model example suggest that the use of simulation models may enhance the understanding and debate about existing and new socioeconomic inequalities of health frameworks.
Powertrain modeling and simulation for off-road vehicles
Ouellette, S. [McGill Univ., Montreal, PQ (Canada)
2010-07-01
Standard forward facing automotive powertrain modeling and simulation methodology did not perform equally for all vehicles in all applications in the 2010 winter Olympics, 2009 world alpine ski championships, summit station in Greenland, the McGill Formula Hybrid, Unicell QuickSider, and lunar mobility. This presentation provided a standard automotive powertrain modeling and simulation flow chart as well as an example. It also provided a flow chart for location based powertrain modeling and simulation and discussed location based powertrain modeling and simulation implementation. It was found that in certain applications, vehicle-environment interactions cannot be neglected in order to have good model fidelity. Powertrain modeling and simulation of off-road vehicles demands a new approach to powertrain modeling and simulation. It was concluded that the proposed location based methodology could improve the results for off-road vehicles. tabs., figs.
A Simulation Model for Evaluating Distributed Systems Dependability
Dobre, Ciprian; Cristea, Valentin
2012-01-01
In this paper we present a new simulation model designed to evaluate the dependability in distributed systems. This model extends the MONARC simulation model with new capabilities for capturing reliability, safety, availability, security, and maintainability requirements. The model has been implemented as an extension of the multithreaded, process oriented simulator MONARC, which allows the realistic simulation of a wide-range of distributed system technologies, with respect to their specific components and characteristics. The extended simulation model includes the necessary components to inject various failure events, and provides the mechanisms to evaluate different strategies for replication, redundancy procedures, and security enforcement mechanisms, as well. The results obtained in simulation experiments presented in this paper probe that the use of discrete-event simulators, such as MONARC, in the design and development of distributed systems is appealing due to their efficiency and scalability.
Parallel Exhibits: Combining Physical and Virtual Exhibits
L. Lischke; T. Dingler; S. Schneegaß; A. Schmidt; M. van der Vaart; P. Wozniak
2014-01-01
People have a special fascination for original physical objects, their texture, and visible history. However, the digitization of exhibits and the use of these data is a current challenge for museums. We believe that museums need to capitalize on the affordances of physical exhibits to help users na
Sunspot Modeling: From Simplified Models to Radiative MHD Simulations
Rolf Schlichenmaier
2011-09-01
Full Text Available We review our current understanding of sunspots from the scales of their fine structure to their large scale (global structure including the processes of their formation and decay. Recently, sunspot models have undergone a dramatic change. In the past, several aspects of sunspot structure have been addressed by static MHD models with parametrized energy transport. Models of sunspot fine structure have been relying heavily on strong assumptions about flow and field geometry (e.g., flux-tubes, "gaps", convective rolls, which were motivated in part by the observed filamentary structure of penumbrae or the necessity of explaining the substantial energy transport required to maintain the penumbral brightness. However, none of these models could self-consistently explain all aspects of penumbral structure (energy transport, filamentation, Evershed flow. In recent years, 3D radiative MHD simulations have been advanced dramatically to the point at which models of complete sunspots with sufficient resolution to capture sunspot fine structure are feasible. Here overturning convection is the central element responsible for energy transport, filamentation leading to fine-structure and the driving of strong outflows. On the larger scale these models are also in the progress of addressing the subsurface structure of sunspots as well as sunspot formation. With this shift in modeling capabilities and the recent advances in high resolution observations, the future research will be guided by comparing observation and theory.
Predictive Capability Maturity Model for computational modeling and simulation.
Oberkampf, William Louis; Trucano, Timothy Guy; Pilch, Martin M.
2007-10-01
The Predictive Capability Maturity Model (PCMM) is a new model that can be used to assess the level of maturity of computational modeling and simulation (M&S) efforts. The development of the model is based on both the authors experience and their analysis of similar investigations in the past. The perspective taken in this report is one of judging the usefulness of a predictive capability that relies on the numerical solution to partial differential equations to better inform and improve decision making. The review of past investigations, such as the Software Engineering Institute's Capability Maturity Model Integration and the National Aeronautics and Space Administration and Department of Defense Technology Readiness Levels, indicates that a more restricted, more interpretable method is needed to assess the maturity of an M&S effort. The PCMM addresses six contributing elements to M&S: (1) representation and geometric fidelity, (2) physics and material model fidelity, (3) code verification, (4) solution verification, (5) model validation, and (6) uncertainty quantification and sensitivity analysis. For each of these elements, attributes are identified that characterize four increasing levels of maturity. Importantly, the PCMM is a structured method for assessing the maturity of an M&S effort that is directed toward an engineering application of interest. The PCMM does not assess whether the M&S effort, the accuracy of the predictions, or the performance of the engineering system satisfies or does not satisfy specified application requirements.
Simulation modeling for long duration spacecraft control systems
Boyd, Mark A.; Bavuso, Salvatore J.
1993-01-01
The use of simulation is described and it is contrasted to analytical solution techniques for evaluation of analytical reliability models. The role importance sampling plays in simulation of models of this type was also discussed. The simulator tool used for our analysis is described. Finally, the use of the simulator tool was demonstrated by applying it to evaluate the reliability of a fault tolerant hypercube multiprocessor intended for spacecraft designed for long duration missions. The reliability analysis was used to highlight the advantages and disadvantages offered by simulation over analytical solution of Markovian and non-Markovian reliability models.
A new model to simulate impact breakup
Cordelli, Alessandro; Farinella, Paolo
1997-12-01
We have developed a preliminary version of a new type of code to simulate the outcomes of impacts between solid bodies, which we plan to further refine for application to both asteroid science and space debris studies. In the current code, colliding objects are modeled as two-dimensional arrays of finite elements, which can interact with each other in both an elastic and a shock-wave regime. The finite elements are hard spheres with a given value for mass and radius. When two of them come into contact the laws of inelastic scattering are applied, thus giving rise to the propagation of shock waves. Moreover each spherical element interacts elastically with its nearest neighbours. The interaction force corresponds to that of a spring having an equilibrium length equal to the lattice spacing, and results into the propagation of elastic waves in the lattice. Dissipation effects are modeled by means of a dissipative force term proportional to the relative velocity, with a given characteristic time of decay. The possible occurrence of fractures in the material is modeled by assuming that when the distance of two neighbouring elements exceeds a threshold value, the binding force between them disappears for ever. This model requires finding a plausible correspondence between the input parameters appearing in the equations of motion, and the physical properties of real solid materials. Some of the required links are quite obvious (e.g., the relationship between mass of the elements and elastic constant on one side, and material density and sound velocity on the other side), some others a priori are unclear, and additional hypotheses on them must be made (e.g., on the restitution coefficient of inelastic scattering). Despite the preliminary character of the model, we have obtained some interesting results, which appear to mimic in a realistic way the outcomes of actual impacts. For instance, we have observed the formation of craters and fractures, and (for high impact
H. W. Ter Maat
2010-08-01
Full Text Available This paper is a case study to investigate what the main controlling factors are that determine atmospheric carbon dioxide content for a region in the centre of The Netherlands. We use the Regional Atmospheric Modelling System (RAMS, coupled with a land surface scheme simulating carbon, heat and momentum fluxes (SWAPS-C, and including also submodels for urban and marine fluxes, which in principle should include the dominant mechanisms and should be able to capture the relevant dynamics of the system. To validate the model, observations are used that were taken during an intensive observational campaign in central Netherlands in summer 2002. These include flux-tower observations and aircraft observations of vertical profiles and spatial fluxes of various variables.
The simulations performed with the coupled regional model (RAMS-SWAPS-C are in good qualitative agreement with the observations. The station validation of the model demonstrates that the incoming shortwave radiation and surface fluxes of water and CO_{2} are well simulated. The comparison against aircraft data shows that the regional meteorology (i.e. wind, temperature is captured well by the model. Comparing spatially explicitly simulated fluxes with aircraft observed fluxes we conclude that in general latent heat fluxes are underestimated by the model compared to the observations but that the latter exhibit large variability within all flights. Sensitivity experiments demonstrate the relevance of the urban emissions of carbon dioxide for the carbon balance in this particular region. The same tests also show the relation between uncertainties in surface fluxes and those in atmospheric concentrations.
Beyond Modeling: All-Atom Olfactory Receptor Model Simulations
Peter C Lai
2012-05-01
Full Text Available Olfactory receptors (ORs are a type of GTP-binding protein-coupled receptor (GPCR. These receptors are responsible for mediating the sense of smell through their interaction with odor ligands. OR-odorant interactions marks the first step in the process that leads to olfaction. Computational studies on model OR structures can validate experimental functional studies as well as generate focused and novel hypotheses for further bench investigation by providing a view of these interactions at the molecular level. Here we have shown the specific advantages of simulating the dynamic environment that is associated with OR-odorant interactions. We present a rigorous methodology that ranges from the creation of a computationally-derived model of an olfactory receptor to simulating the interactions between an OR and an odorant molecule. Given the ubiquitous occurrence of GPCRs in the membranes of cells, we anticipate that our OR-developed methodology will serve as a model for the computational structural biology of all GPCRs.
Aero-acoustic modeling using large eddy simulation
Shen, Wen Zhong; Sørensen, Jens Nørkær
2007-01-01
The splitting technique for aero-acoustic computations is extended to simulate three-dimensional flow and acoustic waves from airfoils. The aero-acoustic model is coupled to a sub-grid-scale turbulence model for Large-Eddy Simulations. In the first test case, the model is applied to compute laminar...
IDEF method-based simulation model design and development framework
Ki-Young Jeong
2009-09-01
Full Text Available The purpose of this study is to provide an IDEF method-based integrated framework for a business process simulation model to reduce the model development time by increasing the communication and knowledge reusability during a simulation project. In this framework, simulation requirements are collected by a function modeling method (IDEF0 and a process modeling method (IDEF3. Based on these requirements, a common data model is constructed using the IDEF1X method. From this reusable data model, multiple simulation models are automatically generated using a database-driven simulation model development approach. The framework is claimed to help both requirement collection and experimentation phases during a simulation project by improving system knowledge, model reusability, and maintainability through the systematic use of three descriptive IDEF methods and the features of the relational database technologies. A complex semiconductor fabrication case study was used as a testbed to evaluate and illustrate the concepts and the framework. Two different simulation software products were used to develop and control the semiconductor model from the same knowledge base. The case study empirically showed that this framework could help improve the simulation project processes by using IDEF-based descriptive models and the relational database technology. Authors also concluded that this framework could be easily applied to other analytical model generation by separating the logic from the data.
Simulation Modeling of a Facility Layout in Operations Management Classes
Yazici, Hulya Julie
2006-01-01
Teaching quantitative courses can be challenging. Similarly, layout modeling and lean production concepts can be difficult to grasp in an introductory OM (operations management) class. This article describes a simulation model developed in PROMODEL to facilitate the learning of layout modeling and lean manufacturing. Simulation allows for the…
Maneuver simulation model of an experimental hovercraft for the Antarctic
Murao, Rinichi
Results of an investigation of a hovercraft model designed for Antarctic conditions are presented. The buoyancy characteristics, the propellant control system, and simulation model control are examined. An ACV (air cushion vehicle) model of the hovercraft is used to examine the flexibility and friction of the skirt. Simulation results are presented which show the performance of the hovercraft.
Quantification of Modelling Uncertainties in Turbulent Flow Simulations
Edeling, W.N.
2015-01-01
The goal of this thesis is to make predictive simulations with Reynolds-Averaged Navier-Stokes (RANS) turbulence models, i.e. simulations with a systematic treatment of model and data uncertainties and their propagation through a computational model to produce predictions of quantities of interest w
Quantification of Modelling Uncertainties in Turbulent Flow Simulations
Edeling, W.N.
2015-01-01
The goal of this thesis is to make predictive simulations with Reynolds-Averaged Navier-Stokes (RANS) turbulence models, i.e. simulations with a systematic treatment of model and data uncertainties and their propagation through a computational model to produce predictions of quantities of interest
Simulation Modeling of a Facility Layout in Operations Management Classes
Yazici, Hulya Julie
2006-01-01
Teaching quantitative courses can be challenging. Similarly, layout modeling and lean production concepts can be difficult to grasp in an introductory OM (operations management) class. This article describes a simulation model developed in PROMODEL to facilitate the learning of layout modeling and lean manufacturing. Simulation allows for the…
Historical Development of Simulation Models of Recreation Use
Jan W. van Wagtendonk; David N. Cole
2005-01-01
The potential utility of modeling as a park and wilderness management tool has been recognized for decades. Romesburg (1974) explored how mathematical decision modeling could be used to improve decisions about regulation of wilderness use. Cesario (1975) described a computer simulation modeling approach that utilized GPSS (General Purpose Systems Simulator), a...
A simulation model of a star computer network
Gomaa, H
1979-01-01
A simulation model of the CERN (European Organization for Nuclear Research) SPS star computer network is described. The model concentrates on simulating the message handling computer, through which all messages in the network pass. The implementation of the model and its calibration are also described. (6 refs).
无
2002-01-01
Water yield and sediment yield in the Teba catchment, Spain, were simulated using SWRRB (Simulator for Water Resources in Rural Basins) model. The model is composed of 198 mathematical equations. About 120 items (variables) were input for the simulation, including meteorological and climatic factors, hydrologic factors, topographic factors, parent materials, soils, vegetation, human activities, etc. The simulated results involved surface runoff, subsurface runoff, sediment, peak flow, evapotranspiration, soil water, total biomass,etc. Careful and thorough input data preparation and repeated simulation experiments are the key to get the accurate results. In this work the simulation accuracy for annual water yield prediction reached to 83.68%.``
Four Models of In Situ Simulation
Musaeus, Peter; Krogh, Kristian; Paltved, Charlotte
2014-01-01
that there are four fruitful approaches to in situ simulation: (1) In situ simulation informed by reported critical incidents and adverse events from emergency departments (ED) in which team training is about to be conducted to write scenarios. (2) In situ simulation through ethnographic studies at the ED. (3) Using...... prewritten scenarios from the simulation lab and transferring them to in situ simulation. (4) Action research – insider or participant action research to obtain in-depth understanding of team processes to guide scenario design. We evaluate the approach relying on Marks’ et al. taxonomy that posits...... the following processes: Transition processes, Action processes and Interpersonal processes. Design and purpose This abstract suggests four approaches to in situ simulation. A pilot study will evaluate the different approaches in two emergency departments in the Central Region of Denmark. Methods The typology...
Bertin; CERN PhotoLab
1969-01-01
The United Kingdom inaugurated the Industrial Exhibitions in 1968, and it wasn't till 1971 that other countries staged exhibitions at CERN. This photo was taken in 1969, at the second British exhibition, where 16 companies were present.
A New Model for Simulating TSS Washoff in Urban Areas
E. Crobeddu
2011-01-01
Full Text Available This paper presents the formulation and validation of the conceptual Runoff Quality Simulation Model (RQSM that was developed to simulate the erosion and transport of solid particles in urban areas. The RQSM assumes that solid particle accumulation on pervious and impervious areas is infinite. The RQSM simulates soil erosion using rainfall kinetic energy and solid particle transport with linear system theory. A sensitivity analysis was conducted on the RQSM to show the influence of each parameter on the simulated load. Total suspended solid (TSS loads monitored at the outlet of the borough of Verdun in Canada and at three catchment outlets of the City of Champaign in the United States were used to validate the RQSM. TSS loads simulated by the RQSM were compared to measured loads and to loads simulated by the Rating Curve model and the Exponential model of the SWMM software. The simulation performance of the RQSM was comparable to the Exponential and Rating Curve models.
An Integrated Approach to Flexible Modelling and Animated Simulation
Li Shuliang; Wu Zhenye
1994-01-01
Based on the software support of SIMAN/CINEMA, this paper presents an integrated approach to flexible modelling and simulation with animation. The methodology provides a structured way of integrating mathematical and logical model, statistical experinentation, and statistical analysis with computer animation. Within this methodology, an animated simulation study is separated into six different activities: simulation objectives identification , system model development, simulation experiment specification, animation layout construction, real-time simulation and animation run, and output data analysis. These six activities are objectives driven, relatively independent, and integrate through software organization and simulation files. The key ideas behind this methodology are objectives orientation, modelling flexibility,simulation and animation integration, and application tailorability. Though the methodology is closely related to SIMAN/CINEMA, it can be extended to other software environments.
Evaluation of Marine Corps Manpower Computer Simulation Model
2016-12-01
MARINE CORPS MANPOWER COMPUTER SIMULATION MODEL by Eric S. Anderson December 2016 Thesis Advisor: Arnold Buss Second Reader: Neil Rowe...Master’s thesis 4. TITLE AND SUBTITLE EVALUATION OF MARINE CORPS MANPOWER COMPUTER SIMULATION MODEL 5. FUNDING NUMBERS ACCT: 622716 JON...overall end strength are maintained. To assist their mission, an agent-based computer simulation model was developed in the Java computer language
Business Process Simulation: Requirements for Business and Resource Models
Audrius Rima
2015-07-01
Full Text Available The purpose of Business Process Model and Notation (BPMN is to provide easily understandable graphical representation of business process. Thus BPMN is widely used and applied in various areas one of them being a business process simulation. This paper addresses some BPMN model based business process simulation problems. The paper formulate requirements for business process and resource models in enabling their use for business process simulation.
Discrete Event Simulation Modeling and Analysis of Key Leader Engagements
2012-06-01
SIMULATION MODELING AND ANALYSIS OF KEY LEADER ENGAGEMENTS by Clifford C. Wakeman June 2012 Thesis Co-Advisors: Arnold H. Buss Susan...DATE June 2012 3. REPORT TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE Discrete Event Simulation Modeling and Analysis of Key...for public release; distribution is unlimited DISCRETE EVENT SIMULATION MODELING AND ANALYSIS OF KEY LEADER ENGAGEMENTS Clifford C. Wakeman
The COD Model: Simulating Workgroup Performance
Biggiero, Lucio; Sevi, Enrico
Though the question of the determinants of workgroup performance is one of the most central in organization science, precise theoretical frameworks and formal demonstrations are still missing. In order to fill in this gap the COD agent-based simulation model is here presented and used to study the effects of task interdependence and bounded rationality on workgroup performance. The first relevant finding is an algorithmic demonstration of the ordering of interdependencies in terms of complexity, showing that the parallel mode is the most simplex, followed by the sequential and then by the reciprocal. This result is far from being new in organization science, but what is remarkable is that now it has the strength of an algorithmic demonstration instead of being based on the authoritativeness of some scholar or on some episodic empirical finding. The second important result is that the progressive introduction of realistic limits to agents' rationality dramatically reduces workgroup performance and addresses to a rather interesting result: when agents' rationality is severely bounded simple norms work better than complex norms. The third main finding is that when the complexity of interdependence is high, then the appropriate coordination mechanism is agents' direct and active collaboration, which means teamwork.
Diversity modelling for electrical power system simulation
Sharip, R. M.; Abu Zarim, M. A. U. A.
2013-12-01
This paper considers diversity of generation and demand profiles against the different future energy scenarios and evaluates these on a technical basis. Compared to previous studies, this research applied a forecasting concept based on possible growth rates from publically electrical distribution scenarios concerning the UK. These scenarios were created by different bodies considering aspects such as environment, policy, regulation, economic and technical. In line with these scenarios, forecasting is on a long term timescale (up to every ten years from 2020 until 2050) in order to create a possible output of generation mix and demand profiles to be used as an appropriate boundary condition for the network simulation. The network considered is a segment of rural LV populated with a mixture of different housing types. The profiles for the 'future' energy and demand have been successfully modelled by applying a forecasting method. The network results under these profiles shows for the cases studied that even though the value of the power produced from each Micro-generation is often in line with the demand requirements of an individual dwelling there will be no problems arising from high penetration of Micro-generation and demand side management for each dwellings considered. The results obtained highlight the technical issues/changes for energy delivery and management to rural customers under the future energy scenarios.
Osaki, Yoshinori; Nakagawa, Yoshimi; Miyahara, Shoko; Iwasaki, Hitoshi; Ishii, Akiko; Matsuzaka, Takashi; Kobayashi, Kazuto; Yatoh, Shigeru; Takahashi, Akimitsu; Yahagi, Naoya; Suzuki, Hiroaki; Sone, Hirohito; Ohashi, Ken; Ishibashi, Shun; Yamada, Nobuhiro; Shimano, Hitoshi
2015-10-23
HMG-CoA reductase (HMGCR) catalyzes the conversion of HMG-CoA to mevalonic acid (MVA); this is the rate-limiting enzyme of the mevalonate pathway that synthesizes cholesterol. Statins, HMGCR inhibitors, are widely used as cholesterol-reducing drugs. However, statin-induced myopathy is the most adverse side effect of statins. To eludicate the mechanisms underlying statin the myotoxicity and HMGCR function in the skeletal muscle, we developed the skeletal muscle-specific HMGCR knockout mice. Knockout mice exhibited postnatal myopathy with elevated serum creatine kinase levels and necrosis. Myopathy in knockout mice was completely rescued by the oral administration of MVA. These results suggest that skeletal muscle toxicity caused by statins is dependent on the deficiencies of HMGCR enzyme activity and downstream metabolites of the mevalonate pathway in skeletal muscles rather than the liver or other organs. Copyright © 2015 Elsevier Inc. All rights reserved.
Graph model of behavior simulator. [Interactive simulator developed as part of UCLA SARA system
Razouk, R.R.; Estrin, G.
1966-01-01
An interactive simulator developed at UCLA as part of the SARA system is described. This simulator, in conjunction with other design tools of the SARA system, allows the user to model the behavior of the system being designed at various levels of detail. The models which drive the simulator are control graphs and associated data graphs. The simulator uses the control graph to express synchronization of sequences of events. Initiation of any control node triggers the simulator to call on the data graph model to provide interpretation of a process at a desired level of abstraction. The simulator gives the user the capability to examine, or modify, the state of the control and data graphs during a simulation. 8 figures.
Modeling, Simulation and Position Control of 3DOF Articulated Manipulator
Hossein Sadegh Lafmejani
2014-08-01
Full Text Available In this paper, the modeling, simulation and control of 3 degrees of freedom articulated robotic manipulator have been studied. First, we extracted kinematics and dynamics equations of the mentioned manipulator by using the Lagrange method. In order to validate the analytical model of the manipulator we compared the model simulated in the simulation environment of Matlab with the model was simulated with the SimMechanics toolbox. A sample path has been designed for analyzing the tracking subject. The system has been linearized with feedback linearization and then a PID controller was applied to track a reference trajectory. Finally, the control results have been compared with a nonlinear PID controller.
Runoff Simulation of Shitoukoumen Reservoir Basin Based on SWAT Model
XIE; Miao; LI; Hong-yan; LIU; Tie-juan; RU; Shi-rong
2012-01-01
[Objective]The study aimed to simulate the runoff of Shitoukoumen Reservoir basin by using SWAT model. [Method] Based on DEM elevation, land use type, soil type and hydrometeorological data, SWAT model, a distributed hydrological model was established to simulate the monthly runoff of Shitoukoumen Reservoir basin, and the years 2006 and 2010 were chosen as the calibration and validation period respectively. [Result] The simulation results indicated that SWAT model could be used to simulate the runoff of Shitoukoumen Reservoir basin, and the simulation effect was good. However, the response of the model to local rainstorm was not obvious, so that the actual runoff in June and July of 2010 was abnormally higher than the simulation value. [Conclusion] The research could provide theoretical references for the plan and management of water resources in Shitoukoumen Reservoir basin in future.
A model for educational simulation of infant cardiovascular physiology.
Goodwin, Jane A; van Meurs, Willem L; Sá Couto, Carla D; Beneken, Jan E W; Graves, Shirley A
2004-12-01
Full-body patient simulators provide the technology and the environment necessary for excellent clinical education while eliminating risk to the patient. The extension of simulator-based training into management of basic and critical situations in complex patient populations is natural. We describe the derivation of an infant cardiovascular model through the redefinition of a complete set of parameters for an existing adult model. Specifically, we document a stepwise parameter estimation process, explicit simplifying assumptions, and sources for these parameters. The simulated vital signs are within the target hemodynamic variables, and the simulated systemic arterial pressure wave form and left ventricular pressure volume loop are realistic. The system reacts appropriately to blood loss, and incorporation of aortic stenosis is straightforward. This infant cardiovascular model can form the basis for screen-based educational simulations. The model is also an essential step in attaining a full-body, model-driven infant simulator.
Qualitative and Quantitative Integrated Modeling for Stochastic Simulation and Optimization
Xuefeng Yan
2013-01-01
Full Text Available The simulation and optimization of an actual physics system are usually constructed based on the stochastic models, which have both qualitative and quantitative characteristics inherently. Most modeling specifications and frameworks find it difficult to describe the qualitative model directly. In order to deal with the expert knowledge, uncertain reasoning, and other qualitative information, a qualitative and quantitative combined modeling specification was proposed based on a hierarchical model structure framework. The new modeling approach is based on a hierarchical model structure which includes the meta-meta model, the meta-model and the high-level model. A description logic system is defined for formal definition and verification of the new modeling specification. A stochastic defense simulation was developed to illustrate how to model the system and optimize the result. The result shows that the proposed method can describe the complex system more comprehensively, and the survival probability of the target is higher by introducing qualitative models into quantitative simulation.
Theory, modeling and simulation of superconducting qubits
Berman, Gennady P [Los Alamos National Laboratory; Kamenev, Dmitry I [Los Alamos National Laboratory; Chumak, Alexander [INSTIT OF PHYSICS, KIEV; Kinion, Carin [LLNL; Tsifrinovich, Vladimir [POLYTECHNIC INSTIT OF NYU
2011-01-13
We analyze the dynamics of a qubit-resonator system coupled with a thermal bath and external electromagnetic fields. Using the evolution equations for the set of Heisenberg operators that describe the whole system, we derive an expression for the resonator field, that includes the resonator-drive, the resonator-bath, and resonator-qubit interactions. The renormalization of the resonator frequency, caused by the qubit-resonator interaction, is accounted for. Using the solutions for the resonator field, we derive the equation that describes the qubit dynamics. The dependence of the qubit evolution during the measurement time on the fidelity of a single-shot measurement is studied. The relation between the fidelity and measurement time is shown explicitly. We proposed a novel adiabatic method for the phase qubit measurement. The method utilizes a low-frequency, quasi-classical resonator inductively coupled to the qubit. The resonator modulates the qubit energy, and the back reaction of the qubit causes a shift in the phase of the resonator. The resonator phase shift can be used to determine the qubit state. We have simulated this measurement taking into the account the energy levels outside the phase qubit manifold. We have shown that, for qubit frequencies in the range of 8-12GHZ, a resonator frequency of 500 MHz and a measurement time of 100 ns, the phase difference between the two qubit states is greater than 0.2 rad. This phase difference exceeds the measurement uncertainty, and can be detected using a classical phase-meter. A fidelity of 0.9999 can be achieved for a relaxation time of 0.5 ms. We also model and simulate a microstrip-SQUID amplifier of frequency about 500 MHz, which could be used to amplify the resonator oscillations in the phase qubit adiabatic measurement. The voltage gain and the amplifier noise temperature are calculated. We simulate the preparation of a generalized Bell state and compute the relaxation times required for achieving high
Theory, modeling and simulation of superconducting qubits
Berman, Gennady P [Los Alamos National Laboratory; Kamenev, Dmitry I [Los Alamos National Laboratory; Chumak, Alexander [INSTIT OF PHYSICS, KIEV; Kinion, Carin [LLNL; Tsifrinovich, Vladimir [POLYTECHNIC INSTIT OF NYU
2011-01-13
We analyze the dynamics of a qubit-resonator system coupled with a thermal bath and external electromagnetic fields. Using the evolution equations for the set of Heisenberg operators that describe the whole system, we derive an expression for the resonator field, that includes the resonator-drive, the resonator-bath, and resonator-qubit interactions. The renormalization of the resonator frequency, caused by the qubit-resonator interaction, is accounted for. Using the solutions for the resonator field, we derive the equation that describes the qubit dynamics. The dependence of the qubit evolution during the measurement time on the fidelity of a single-shot measurement is studied. The relation between the fidelity and measurement time is shown explicitly. We proposed a novel adiabatic method for the phase qubit measurement. The method utilizes a low-frequency, quasi-classical resonator inductively coupled to the qubit. The resonator modulates the qubit energy, and the back reaction of the qubit causes a shift in the phase of the resonator. The resonator phase shift can be used to determine the qubit state. We have simulated this measurement taking into the account the energy levels outside the phase qubit manifold. We have shown that, for qubit frequencies in the range of 8-12GHZ, a resonator frequency of 500 MHz and a measurement time of 100 ns, the phase difference between the two qubit states is greater than 0.2 rad. This phase difference exceeds the measurement uncertainty, and can be detected using a classical phase-meter. A fidelity of 0.9999 can be achieved for a relaxation time of 0.5 ms. We also model and simulate a microstrip-SQUID amplifier of frequency about 500 MHz, which could be used to amplify the resonator oscillations in the phase qubit adiabatic measurement. The voltage gain and the amplifier noise temperature are calculated. We simulate the preparation of a generalized Bell state and compute the relaxation times required for achieving high
MODEL OF HEAT SIMULATOR FOR DATA CENTERS
Jan Novotný
2016-08-01
Full Text Available The aim of this paper is to present a design and a development of a heat simulator, which will be used for a flow research in data centers. The designed heat simulator is based on an ideological basis of four-processor 1U Supermicro server. The designed heat simulator enables to control the flow and heat output within the range of 10–100 %. The paper covers also the results of testing measurements of mass flow rates and heat flow rates in the simulator. The flow field at the outlet of the server was measured by the stereo PIV method. The heat flow rate was determined, based on measuring the temperature field at the inlet and outlet of the simulator and known mass flow rate.
Andressoo, Jaan-Olle; Mitchell, James R; Wit, Jan de; Hoogstraten, Deborah; Volker, Marcel; Toussaint, Wendy; Speksnijder, Ewoud; Beems, Rudolf B; Steeg, Harry van; Jans, Judith; Zeeuw, Chris I de; Jaspers, Nicolaas G J; Raams, Anja; Lehmann, Alan R; Vermeulen, Wim; Hoeijmakers, Jan H J; Horst, Gijsbertus T J van der
2006-01-01
Inborn defects in nucleotide excision DNA repair (NER) can paradoxically result in elevated cancer incidence (xeroderma pigmentosum [XP]) or segmental progeria without cancer predisposition (Cockayne syndrome [CS] and trichothiodystrophy [TTD]). We report generation of a knockin mouse model for the
Andressoo, Jaan-Olle; Mitchell, James R; Wit, Jan de; Hoogstraten, Deborah; Volker, Marcel; Toussaint, Wendy; Speksnijder, Ewoud; Beems, Rudolf B; Steeg, Harry van; Jans, Judith; Zeeuw, Chris I de; Jaspers, Nicolaas G J; Raams, Anja; Lehmann, Alan R; Vermeulen, Wim; Hoeijmakers, Jan H J; Horst, Gijsbertus T J van der
2006-01-01
Inborn defects in nucleotide excision DNA repair (NER) can paradoxically result in elevated cancer incidence (xeroderma pigmentosum [XP]) or segmental progeria without cancer predisposition (Cockayne syndrome [CS] and trichothiodystrophy [TTD]). We report generation of a knockin mouse model for the
Research on system architecture of modeling and simulation
WANG Jiangyun; WANG Xingren
2007-01-01
The modeling and simulation(M&S)architecture describes and defines the relationship between the difeerent parts of a simulation.The simulation system architecture and simulation support platform architecture are discussed separately.The simulation support platform architecture consists of the management layer,the resource layer,the communication layer,the application layer and the infrastructure layer.The best Wav is to design and realize the M&S collaborative environment for simulation support platform in the resource-communication-application three-dimension space.
Relative importance of secondary settling tank models in WWTP simulations
Ramin, Elham; Flores-Alsina, Xavier; Sin, Gürkan
2012-01-01
Results obtained in a study using the Benchmark Simulation Model No. 1 (BSM1) show that a one-dimensional secondary settling tank (1-D SST) model structure and its parameters are among the most significant sources of uncertainty in wastewater treatment plant (WWTP) simulations [Ramin et al., 2011......]. The sensitivity results consistently indicate that the prediction of sludge production is most sensitive to the variation of the settling parameters. In the present study, we use the Benchmark Simulation Model No. 2 (BSM2), a plant-wide benchmark, that combines the Activated Sludge Model No. 1 (ASM1......) with the Anaerobic Digestion Model No. 1 (ADM1). We use BSM2 as a vehicle to compare two different 1-D SST models, and to assess the relative significance of their performance on WWTP simulation model outputs. The two 1-D SST models assessed include the firstorder model by Takács et al. [1991] and the second...
Optimisation of a Crossdocking Distribution Centre Simulation Model
Adewunmi, Adrian
2010-01-01
This paper reports on continuing research into the modelling of an order picking process within a Crossdocking distribution centre using Simulation Optimisation. The aim of this project is to optimise a discrete event simulation model and to understand factors that affect finding its optimal performance. Our initial investigation revealed that the precision of the selected simulation output performance measure and the number of replications required for the evaluation of the optimisation objective function through simulation influences the ability of the optimisation technique. We experimented with Common Random Numbers, in order to improve the precision of our simulation output performance measure, and intended to use the number of replications utilised for this purpose as the initial number of replications for the optimisation of our Crossdocking distribution centre simulation model. Our results demonstrate that we can improve the precision of our selected simulation output performance measure value using C...
Simulating colloids with Baxter's adhesive hard sphere model
Miller, M.A.; Frenkel, D.
2004-01-01
The structure of the Baxter adhesive hard sphere fluid is examined using computer simulation. The radial distribution function (which exhibits unusual discontinuities due to the particle adhesion) and static structure factor are calculated with high accuracy over a range of conditions and compared w
Simulating colloids with Baxter's adhesive hard sphere model
Miller, M.A.; Frenkel, D.
2004-01-01
The structure of the Baxter adhesive hard sphere fluid is examined using computer simulation. The radial distribution function (which exhibits unusual discontinuities due to the particle adhesion) and static structure factor are calculated with high accuracy over a range of conditions and compared
On-line simulations of models for backward masking.
Francis, Gregory
2003-11-01
Five simulations of quantitative models of visual backward masking are available on the Internet at http://www.psych.purdue.edu/-gfrancis/Publications/BackwardMasking/. The simulations can be run in a Web browser that supports the Java programming language. This article describes the motivation for making the simulations available and gives a brief introduction as to how the simulations are used. The source code is available on the Web page, and this article describes how the code is organized.
Theory of compressive modeling and simulation
Szu, Harold; Cha, Jae; Espinola, Richard L.; Krapels, Keith
2013-05-01
Modeling and Simulation (M&S) has been evolving along two general directions: (i) data-rich approach suffering the curse of dimensionality and (ii) equation-rich approach suffering computing power and turnaround time. We suggest a third approach. We call it (iii) compressive M&S (CM&S); because the basic Minimum Free-Helmholtz Energy (MFE) facilitating CM&S can reproduce and generalize Candes, Romberg, Tao & Donoho (CRT&D) Compressive Sensing (CS) paradigm as a linear Lagrange Constraint Neural network (LCNN) algorithm. CM&S based MFE can generalize LCNN to 2nd order as Nonlinear augmented LCNN. For example, during the sunset, we can avoid a reddish bias of sunlight illumination due to a long-range Rayleigh scattering over the horizon. With CM&S we can take instead of day camera, a night vision camera. We decomposed long wave infrared (LWIR) band with filter into 2 vector components (8~10μm and 10~12μm) and used LCNN to find pixel by pixel the map of Emissive-Equivalent Planck Radiation Sources (EPRS). Then, we up-shifted consistently, according to de-mixed sources map, to the sub-micron RGB color image. Moreover, the night vision imaging can also be down-shifted at Passive Millimeter Wave (PMMW) imaging, suffering less blur owing to dusty smokes scattering and enjoying apparent smoothness of surface reflectivity of man-made objects under the Rayleigh resolution. One loses three orders of magnitudes in the spatial Rayleigh resolution; but gains two orders of magnitude in the reflectivity, and gains another two orders in the propagation without obscuring smog . Since CM&S can generate missing data and hard to get dynamic transients, CM&S can reduce unnecessary measurements and their associated cost and computing in the sense of super-saving CS: measuring one & getting one's neighborhood free .
Nanoindentation shape effect: experiments, simulations and modelling
Calabri, L [CNR-INFM-National Research Center on nanoStructures and bioSystems at Surfaces (S3), Via Campi 213/a, 41100 Modena (Italy); Pugno, N [Department of Structural Engineering, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Turin (Italy); Rota, A [CNR-INFM-National Research Center on nanoStructures and bioSystems at Surfaces (S3), Via Campi 213/a, 41100 Modena (Italy); Marchetto, D [CNR-INFM-National Research Center on nanoStructures and bioSystems at Surfaces (S3), Via Campi 213/a, 41100 Modena (Italy); Valeri, S [CNR-INFM-National Research Center on nanoStructures and bioSystems at Surfaces (S3), Via Campi 213/a, 41100 Modena (Italy)
2007-10-03
AFM nanoindentation is nowadays commonly used for the study of mechanical properties of materials at the nanoscale. The investigation of surface hardness of a material using AFM means that the probe has to be able to indent the surface, but also to image it. Usually standard indenters are not sharp enough to obtain high-resolution images, but on the other hand measuring the hardness behaviour of a material with a non-standard sharp indenter gives only comparative results affected by a significant deviation from the commonly used hardness scales. In this paper we try to understand how the shape of the indenter affects the hardness measurement, in order to find a relationship between the measured hardness of a material and the corner angle of a pyramidal indenter. To achieve this we performed a full experimental campaign, indenting the same material with three focused ion beam (FIB) nanofabricated probes with a highly altered corner angle. We then compared the results obtained experimentally with those obtained by numerical simulations, using the finite element method (FEM), and by theoretical models, using a general scaling law for nanoindentation available for indenters with a variable size and shape. The comparison between these three approaches (experimental, numerical and theoretical approaches) reveals a good agreement and allowed us to find a theoretical relationship which links the measured hardness value with the shape of the indenter. The same theoretical approach has also been used to fit the hardness experimental results considering the indentation size effect. In this case we compare the measured data, changing the applied load.
Medical simulation: Overview, and application to wound modelling and management
Dinker R Pai
2012-01-01
Full Text Available Simulation in medical education is progressing in leaps and bounds. The need for simulation in medical education and training is increasing because of a overall increase in the number of medical students vis-à-vis the availability of patients; b increasing awareness among patients of their rights and consequent increase in litigations and c tremendous improvement in simulation technology which makes simulation more and more realistic. Simulation in wound care can be divided into use of simulation in wound modelling (to test the effect of projectiles on the body and simulation for training in wound management. Though this science is still in its infancy, more and more researchers are now devising both low-technology and high-technology (virtual reality simulators in this field. It is believed that simulator training will eventually translate into better wound care in real patients, though this will be the subject of further research.
Towards Automatic Processing of Virtual City Models for Simulations
Piepereit, R.; Schilling, A.; Alam, N.; Wewetzer, M.; Pries, M.; Coors, V.
2016-10-01
Especially in the field of numerical simulations, such as flow and acoustic simulations, the interest in using virtual 3D models to optimize urban systems is increasing. The few instances in which simulations were already carried out in practice have been associated with an extremely high manual and therefore uneconomical effort for the processing of models. Using different ways of capturing models in Geographic Information System (GIS) and Computer Aided Engineering (CAE), increases the already very high complexity of the processing. To obtain virtual 3D models suitable for simulation, we developed a tool for automatic processing with the goal to establish ties between the world of GIS and CAE. In this paper we introduce a way to use Coons surfaces for the automatic processing of building models in LoD2, and investigate ways to simplify LoD3 models in order to reduce unnecessary information for a numerical simulation.
Large-scale Monte Carlo simulations for the depinning transition in Ising-type lattice models
Si, Lisha; Liao, Xiaoyun; Zhou, Nengji
2016-12-01
With the developed "extended Monte Carlo" (EMC) algorithm, we have studied the depinning transition in Ising-type lattice models by extensive numerical simulations, taking the random-field Ising model with a driving field and the driven bond-diluted Ising model as examples. In comparison with the usual Monte Carlo method, the EMC algorithm exhibits greater efficiency of the simulations. Based on the short-time dynamic scaling form, both the transition field and critical exponents of the depinning transition are determined accurately via the large-scale simulations with the lattice size up to L = 8912, significantly refining the results in earlier literature. In the strong-disorder regime, a new universality class of the Ising-type lattice model is unveiled with the exponents β = 0.304(5) , ν = 1.32(3) , z = 1.12(1) , and ζ = 0.90(1) , quite different from that of the quenched Edwards-Wilkinson equation.
Understanding Emergency Care Delivery through Computer Simulation Modeling.
Laker, Lauren F; Torabi, Elham; France, Daniel J; Froehle, Craig M; Goldlust, Eric J; Hoot, Nathan R; Kasaie, Parastu; Lyons, Michael S; Barg-Walkow, Laura H; Ward, Michael J; Wears, Robert L
2017-08-10
In 2017, Academic Emergency Medicine convened a consensus conference entitled, "Catalyzing System Change through Health Care Simulation: Systems, Competency, and Outcomes." This manuscript, a product of the breakout session on "understanding complex interactions through systems modeling," explores the role that computer simulation modeling can and should play in research and development of emergency care delivery systems. This manuscript discusses areas central to the use of computer simulation modeling in emergency care research. The four central approaches to computer simulation modeling are described (Monte Carlo Simulation, System Dynamics modeling, Discrete-Event Simulation, and Agent Based Simulation), along with problems amenable to their use and relevant examples to emergency care. Also discussed is an introduction to available software modeling platforms and how to explore their use for research, along with a research agenda for computer simulation modeling. Through this manuscript, our goal is to enhance adoption of computer simulation, a set of methods which hold great promise in addressing emergency care organization and design challenges. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.
Conceptual Modeling for Discrete-Event Simulation
Robinson, Stewart
2010-01-01
What is a conceptual model? How is conceptual modeling performed in general and in specific modeling domains? What is the role of established approaches in conceptual modeling? This book addresses these issues
Mathematical Simulating Model of Phased-Array Antenna in Multifunction Array Radar
无
1999-01-01
A mathematical simulating model of phased-array antenna in multifunction array radar has been approached in this paper, including the mathematical simulating model of plane phased-array pattern, the mathematical simulating model of directionality factor, the mathematical simulating model of array factor, the mathematical simulating model of array element factor and the mathematical simulating model of beam steering.
Hieber, Simone E.; Koumoutsakos, Petros
2008-11-01
We present a novel Lagrangian particle method for the simulation of linear and nonlinear elastic models of soft tissue. Linear solids are represented by the Lagrangian formulation of the stress-strain relationship that is extended to nonlinear solids by using the Lagrangian evolution of the deformation gradient described in a moving framework. The present method introduces a level set description, along with the particles, to capture the body deformations and to enforce the boundary conditions. Furthermore, the accuracy of the method in cases of large deformations is ensured by implementing a particle remeshing procedure. The method is validated in several benchmark problems, in two and three dimensions and the results compare well with the results of respective finite elements simulations. In simulations of large solid deformation under plane strain compression, the finite element solver exhibits spurious structures that are not present in the Lagrangian particle simulations. The particle simulations are compared with experimental results in an aspiration test of liver tissue.
Marshall, Deborah A; Burgos-Liz, Lina; IJzerman, Maarten J; Crown, William; Padula, William V; Wong, Peter K; Pasupathy, Kalyan S; Higashi, Mitchell K; Osgood, Nathaniel D
2015-03-01
In a previous report, the ISPOR Task Force on Dynamic Simulation Modeling Applications in Health Care Delivery Research Emerging Good Practices introduced the fundamentals of dynamic simulation modeling and identified the types of health care delivery problems for which dynamic simulation modeling can be used more effectively than other modeling methods. The hierarchical relationship between the health care delivery system, providers, patients, and other stakeholders exhibits a level of complexity that ought to be captured using dynamic simulation modeling methods. As a tool to help researchers decide whether dynamic simulation modeling is an appropriate method for modeling the effects of an intervention on a health care system, we presented the System, Interactions, Multilevel, Understanding, Loops, Agents, Time, Emergence (SIMULATE) checklist consisting of eight elements. This report builds on the previous work, systematically comparing each of the three most commonly used dynamic simulation modeling methods-system dynamics, discrete-event simulation, and agent-based modeling. We review criteria for selecting the most suitable method depending on 1) the purpose-type of problem and research questions being investigated, 2) the object-scope of the model, and 3) the method to model the object to achieve the purpose. Finally, we provide guidance for emerging good practices for dynamic simulation modeling in the health sector, covering all aspects, from the engagement of decision makers in the model design through model maintenance and upkeep. We conclude by providing some recommendations about the application of these methods to add value to informed decision making, with an emphasis on stakeholder engagement, starting with the problem definition. Finally, we identify areas in which further methodological development will likely occur given the growing "volume, velocity and variety" and availability of "big data" to provide empirical evidence and techniques
Evaluation of a proposed optimization method for discrete-event simulation models
Alexandre Ferreira de Pinho
2012-12-01
Full Text Available Optimization methods combined with computer-based simulation have been utilized in a wide range of manufacturing applications. However, in terms of current technology, these methods exhibit low performance levels which are only able to manipulate a single decision variable at a time. Thus, the objective of this article is to evaluate a proposed optimization method for discrete-event simulation models based on genetic algorithms which exhibits more efficiency in relation to computational time when compared to software packages on the market. It should be emphasized that the variable's response quality will not be altered; that is, the proposed method will maintain the solutions' effectiveness. Thus, the study draws a comparison between the proposed method and that of a simulation instrument already available on the market and has been examined in academic literature. Conclusions are presented, confirming the proposed optimization method's efficiency.
Research on the modeling method of soybean leafs structure simulation
无
2007-01-01
Leaf is one of the most important organs of soybean. The modeling of soybean leaf structure is useful to research of leaf function. The paper discussed it from two aspects that were distilling method of leaf profile and establishing method of leaf simulation model. It put forward basic method of soybean leaf digital process, and successfully established simulation model of soybean leaf structure based on L-system. It also solved a critical problem in the process of establishing soybean growth simulation model. And the research had guiding significance to establishment of soybean plant model.
Stochastic models to simulate paratuberculosis in dairy herds
Nielsen, S.S.; Weber, M.F.; Kudahl, Anne Margrethe Braad
2011-01-01
Stochastic simulation models are widely accepted as a means of assessing the impact of changes in daily management and the control of different diseases, such as paratuberculosis, in dairy herds. This paper summarises and discusses the assumptions of four stochastic simulation models and their use...... the models are somewhat different in their underlying principles and do put slightly different values on the different strategies, their overall findings are similar. Therefore, simulation models may be useful in planning paratuberculosis strategies in dairy herds, although as with all models caution...
A simulation model for forecasting downhill ski participation
Daniel J. Stynes; Daniel M. Spotts
1980-01-01
The purpose of this paper is to describe progress in the development of a general computer simulation model to forecast future levels of outdoor recreation participation. The model is applied and tested for downhill skiing in Michigan.
Logistics of Trainsets Creation with the Use of Simulation Models
Sedláček, Michal; Pavelka, Hynek
2016-12-01
This paper focuses on rail transport in following the train formation operational processes problem using computer simulations. The problem has been solved using SIMUL8 and applied to specific train formation station in the Czech Republic. The paper describes a proposal simulation model of the train formation work. Experimental modeling with an assessment of achievements and design solution for optimizing of the train formation operational process is also presented.
Modeling and Simulation for Design of Suspended MEMS
2003-05-21
simulating systems with complicated electronics is limited. Exporting reduced-order models to aHDLs enables co-simulation with transistor-level...circuit-level behavioral simulation, the models are implemented in analog hardware description languages ( aHDLs ) or directly in element matrices, both...end of module The physical equations could be implemented in the aHDLs in multiple alternative ways. It has been noticed that the language
Cross-Paradigm Simulation Modeling: Challenges and Successes
2011-12-01
This paper addresses the broad topic area of cross-paradigm simulation modeling with a focus on the discrete-event, system dynamics and agent-based...used in simulation modeling are also discussed, and the implications of these mechanisms for each paradigm is explored....and definitions are presented. The difference between the process-oriented worldview and the event-oriented worldview within discrete-event simulation
Software Requirements Specification Verifiable Fuel Cycle Simulation (VISION) Model
D. E. Shropshire; W. H. West
2005-11-01
The purpose of this Software Requirements Specification (SRS) is to define the top-level requirements for a Verifiable Fuel Cycle Simulation Model (VISION) of the Advanced Fuel Cycle (AFC). This simulation model is intended to serve a broad systems analysis and study tool applicable to work conducted as part of the AFCI (including costs estimates) and Generation IV reactor development studies.
Learning-Testing Process in Classroom: An Empirical Simulation Model
Buda, Rodolphe
2009-01-01
This paper presents an empirical micro-simulation model of the teaching and the testing process in the classroom (Programs and sample data are available--the actual names of pupils have been hidden). It is a non-econometric micro-simulation model describing informational behaviors of the pupils, based on the observation of the pupils'…
Active site modeling in copper azurin molecular dynamics simulations
Rizzuti, B; Swart, M; Sportelli, L; Guzzi, R
2004-01-01
Active site modeling in molecular dynamics simulations is investigated for the reduced state of copper azurin. Five simulation runs (5 ns each) were performed at room temperature to study the consequences of a mixed electrostatic/constrained modeling for the coordination between the metal and the po
Object Oriented Toolbox for Modelling and Simulation of Dynamic Systems
Thomsen, Per Grove; Poulsen, Mikael Zebbelin; Wagner, Falko Jens;
1999-01-01
Design and Implementation of a simulation toolbox based on Object Oriented modelling Techniques.Experimental implementation in C++ using the Godess ODE-solution platform.......Design and Implementation of a simulation toolbox based on Object Oriented modelling Techniques.Experimental implementation in C++ using the Godess ODE-solution platform....
Application of computer simulated persons in indoor environmental modeling
Topp, C.; Nielsen, P. V.; Sørensen, Dan Nørtoft
2002-01-01
Computer simulated persons are often applied when the indoor environment is modeled by computational fluid dynamics. The computer simulated persons differ in size, shape, and level of geometrical complexity, ranging from simple box or cylinder shaped heat sources to more humanlike models. Little...
Exploiting Modelling and Simulation in Support of Cyber Defence
Klaver, M.H.A.; Boltjes, B.; Croom-Jonson, S.; Jonat, F.; Çankaya, Y.
2014-01-01
The rapidly evolving environment of Cyber threats against the NATO Alliance has necessitated a renewed focus on the development of Cyber Defence policy and capabilities. The NATO Modelling and Simulation Group is looking for ways to leverage Modelling and Simulation experience in research, analysis
Exploiting Modelling and Simulation in Support of Cyber Defence
Klaver, M.H.A.; Boltjes, B.; Croom-Jonson, S.; Jonat, F.; Çankaya, Y.
2014-01-01
The rapidly evolving environment of Cyber threats against the NATO Alliance has necessitated a renewed focus on the development of Cyber Defence policy and capabilities. The NATO Modelling and Simulation Group is looking for ways to leverage Modelling and Simulation experience in research, analysis
Combat Simulation Modeling in Naval Special Warfare Mission Planning.
1995-12-01
This thesis explores the potential role of combat simulation modeling in the Naval Special Warfare mission planning cycle. It discusses methods for...at the tactical level. The thesis concludes by discussing additional applications of combat simulation modeling within the Naval Special Warfare community and makes recommendations for its effective and efficient implementation.
Flow Through a Laboratory Sediment Sample by Computer Simulation Modeling
2006-09-07
Flow through a laboratory sediment sample by computer simulation modeling R.B. Pandeya’b*, Allen H. Reeda, Edward Braithwaitea, Ray Seyfarth0, J.F...through a laboratory sediment sample by computer simulation modeling 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S
Autonomous underwater vehicles modeling, control design and simulation
Wadoo, Sabiha
2010-01-01
Underwater vehicles present some difficult and very particular control system design problems. These are often the result of nonlinear dynamics and uncertain models, as well as the presence of sometimes unforeseeable environmental disturbances that are difficult to measure or estimate. Autonomous Underwater Vehicles: Modeling, Control Design, and Simulation outlines a novel approach to help readers develop models to simulate feedback controllers for motion planning and design. The book combines useful information on both kinematic and dynamic nonlinear feedback control models, providing simula
Adaptive Simulated Annealing Based Protein Loop Modeling of Neurotoxins
陈杰; 黄丽娜; 彭志红
2003-01-01
A loop modeling method, adaptive simulated annealing, for ab initio prediction of protein loop structures, as an optimization problem of searching the global minimum of a given energy function, is proposed. An interface-friendly toolbox-LoopModeller in Windows and Linux systems, VC++ and OpenGL environments is developed for analysis and visualization. Simulation results of three short-chain neurotoxins modeled by LoopModeller show that the method proposed is fast and efficient.
T=S Model to Simulate Regional Economic Development
WangQing; ChenGuo-jie; ZhangYu; ChenYong
2003-01-01
This paper proposes a mechanism theory on regional development by using a modified Logistic model. It reveals regional evolution is an integration of fluctuation in temporal dimension and disparity in spatial dimension. T=S model is established by using Logistic model to simulate the growth of per capita GDP in China from 1990 to 1999. The result shows that T=S model accurately simulates the tracks of economic growth.
T=S Model to Simulate Regional Economic Development
Wang Qing; Chen Guo-jie; Zhang Yu; Chen Yong
2003-01-01
This paper proposes a mechanism theory on regional development by using a modified Logistic model. It reveals regional evolution is an integration of fluctuation in temporal dimcnsion and disparity in spatial dimension. T = S model is established by using Logistic model to simulate the growth of per capita GDP in China from 1990 to 1999. The result shows that T= S model accurately simulates the tracks of economic growth.
Photodiode Circuit Macro-model for SPICE Simulation
无
2006-01-01
An accurate photodiode circuit macro-model is proposed for SPICE simulation. The definition and implementation of the macro-model is based on carrier stationary continuity equation. In this macro-model, the photodiode is a device of three pins, one for light intensity input and the other two for photocurrent output, which represent the relationship between photocurrent and incident light. The validity of the proposed macro-model is demonstrated with its PSPICE simulation result compared with reported experimental data.
Dynamic wind turbine models in power system simulation tool
Hansen, A.; Jauch, Clemens; Soerensen, P.
The present report describes the dynamic wind turbine models implemented in the power system simulation tool DIgSILENT. The developed models are a part of the results of a national research project, whose overall objective is to create a model database in different simulation tools. The report...... provides a description of the wind turbine modelling, both at a component level and at a system level....
A novel computer simulation for modeling grain growth
Chen, L.Q. (Pennsylvania State Univ., University Park, PA (United States). Dept. of Materials Science and Engineering)
1995-01-01
In this paper, the author proposes a new computer simulation model for investigating grain growth kinetics, born from the recent work on the domain growth kinetics of a quenched system with many non-conserved order parameters. A key new feature of this model for studying grain growth is that the grain boundaries are diffuse, as opposed to previous meanfield and statistical theories and Monte-Carlo simulations which assumed that grain boundaries were sharp. Unlike the Monte-Carlo simulations in which grain boundaries are made up of kinks, grain boundaries in the continuum model are smooth. Below, he describes this model in detail, give prescriptions for computer simulation, and then present computer simulation results on a two-dimensional model system.
Catalog of Wargaming and Military Simulation Models
1989-09-01
Generic Missile Model . MODEL TYPE: Analysis. PROPONENT: WftDC, Avionics Laboratory...requirements. Users: Primarily WRDC/AAWA. Comments: N/A. G-4 TITLE: GFGMMLCM - GEneric Missile Model with Tracking Loops and Counter-Measure SMODEI TYPE...Structure Trade-Off Analysis Model ............ F-31 G2WS - G2 Workstation ................. ..................... C-I GEUI - Generic Missile Model ................................
Hann, Raiford E.
1991-01-01
An equivalent circuit model (ECM) approach is used to predict the scattering behavior of temperature-activated, electrically lossy dielectric layers. The total electrical response of the dielectric (relaxation + conductive) is given by the ECM and used in combination with transmission line theory to compute reflectance spectra for a Dallenbach layer configuration. The effects of thermally-activated relaxation processes on the scattering properties is discussed. Also, the effect of relaxation and conduction activation energy on the electrical properties of the dielectric is described.
Hybrid Modeling and Simulation of Automotive Supply Chain Network
Wen Wang
2013-07-01
Full Text Available According to the operation of automotive supply chain and the features of various simulation methods, we create and simulate a automotive supply chain network model with the core enterprise of two vehicle manufacturers, consisting of several parts suppliers, vehicle distributors and logistics service providers. On this basis of a conceptual model including the establishment of enterprise layer, business layer and operation layer, we establish a detailed model of the network system according to the network structure of automotive supply chain, the operation process and the internal business process of core enterprises; then we use System Dynamics (SD, Discrete Event Simulation (DES and Agent Based Modeling (ABM to describe the operating state of each node in the network model. We execute and analyze the simulation model of the whole network system described by Anylogic, using the results of the distributors’ inventory, inventory cost and customer’s satisfaction to prove the effectiveness of the model.
SDG-based Model Validation in Chemical Process Simulation
张贝克; 许欣; 马昕; 吴重光
2013-01-01
Signed direct graph (SDG) theory provides algorithms and methods that can be applied directly to chemical process modeling and analysis to validate simulation models, and is a basis for the development of a soft-ware environment that can automate the validation activity. This paper is concentrated on the pretreatment of the model validation. We use the validation scenarios and standard sequences generated by well-established SDG model to validate the trends fitted from the simulation model. The results are helpful to find potential problems, as-sess possible bugs in the simulation model and solve the problem effectively. A case study on a simulation model of boiler is presented to demonstrate the effectiveness of this method.
A Simulation and Modeling Framework for Space Situational Awareness
Olivier, S S
2008-09-15
This paper describes the development and initial demonstration of a new, integrated modeling and simulation framework, encompassing the space situational awareness enterprise, for quantitatively assessing the benefit of specific sensor systems, technologies and data analysis techniques. The framework is based on a flexible, scalable architecture to enable efficient, physics-based simulation of the current SSA enterprise, and to accommodate future advancements in SSA systems. In particular, the code is designed to take advantage of massively parallel computer systems available, for example, at Lawrence Livermore National Laboratory. The details of the modeling and simulation framework are described, including hydrodynamic models of satellite intercept and debris generation, orbital propagation algorithms, radar cross section calculations, optical brightness calculations, generic radar system models, generic optical system models, specific Space Surveillance Network models, object detection algorithms, orbit determination algorithms, and visualization tools. The use of this integrated simulation and modeling framework on a specific scenario involving space debris is demonstrated.
Maclean, Kenneth N; Sikora, Jakub; Kožich, Viktor; Jiang, Hua; Greiner, Lori S; Kraus, Eva; Krijt, Jakub; Overdier, Katherine H; Collard, Renata; Brodsky, Gary L; Meltesen, Lynne; Crnic, Linda S; Allen, Robert H; Stabler, Sally P; Elleder, Milan; Rozen, Rima; Patterson, David; Kraus, Jan P
2010-01-01
Cystathionine beta-synthase (CBS) catalyzes the condensation of homocysteine (Hcy) and serine to cystathionine, which is then hydrolyzed to cysteine by cystathionine gamma-lyase. Inactivation of CBS results in CBS-deficient homocystinuria more commonly referred to as classical homocystinuria, which, if untreated, results in mental retardation, thromboembolic complications, and a range of connective tissue disorders. The molecular mechanisms that underlie the pathology of this disease are poorly understood. We report here the generation of a new mouse model of classical homocystinuria in which the mouse cbs gene is inactivated and that exhibits low-level expression of the human CBS transgene under the control of the human CBS promoter. This mouse model, designated "human only" (HO), exhibits severe elevations in both plasma and tissue levels of Hcy, methionine, S-adenosylmethionine, and S-adenosylhomocysteine and a concomitant decrease in plasma and hepatic levels of cysteine. HO mice exhibit mild hepatopathy but, in contrast to previous models of classical homocystinuria, do not incur hepatic steatosis, fibrosis, or neonatal death with approximately 90% of HO mice living for at least 6months. Tail bleeding determinations indicate that HO mice are in a hypercoagulative state that is significantly ameliorated by betaine treatment in a manner that recapitulates the disease as it occurs in humans. Our findings indicate that this mouse model will be a valuable tool in the study of pathogenesis in classical homocystinuria and the rational design of novel treatments. Copyright © 2010 Elsevier Inc. All rights reserved.
Studies of climate dynamics with innovative global-model simulations
Shi, Xiaoming
. Motivated by the fact that natural variability of the atmosphere could obscure the signal of anthropogenic warming on time scales of years to decades, the large scale variability of the atmosphere is also studied. Analysis using simulations in the Community Earth System Model Large Ensemble project reveals that the Northern Annular Mode (NAM) does not have a stable spatial pattern when 50-year long segments of data are used to calculate it. Some segments of data result in NAM-like variability with a very strong North Pacific center of action, while in some others it exhibits a more symmetric structure, with North Pacific and Euro-Atlantic centers of comparable strength. Perhaps somewhat puzzling, the NAM's North Pacific center of action is found to have a strengthening trend under anthropogenic warming. Lastly, the large-scale character of an atmosphere in rotating Radiative-Convective Equilibrium (RCE) is studied, using a global atmospheric model with prescribed globally uniform sea surface temperature and no insolation. In such an equilibrium state, numerous tropical cyclone-like vortices develop in the extratropics, which move slowly poleward and westward. The typical spacing of simulated tropical cyclone-like vortices is comparable to the Rossby radius of deformation, while the production of available potential energy is at a scale slightly smaller than that of the vortices. It is hypothesized that the growth of tropical cyclone-like vortices is driven by the self-aggregation of convection, while baroclinic instability destabilizes any vortices that grow significantly larger than the deformation radius. A weak Hadley circulation dominates in the deep tropics, and an eastward-propagating wavenumber one MJO-like mode with a period of 30 to 40 days develops along the equator.
Sônia Regina Nogueira Ignácio Reis
2007-12-01
Full Text Available An important cytokine role in dengue fever pathogenesis has been described. These molecules can be associated with haemorrhagic manifestations, coagulation disorders, hypotension and shock, all symptoms implicated in vascular permeability and disease worsening conditions. Several immunological diseases have been treated by cytokine modulation and dexamethasone is utilized clinically to treat pathologies with inflammatory and autoimmune ethiologies. We established an in vitro model with human monocytes infected by dengue virus-2 for evaluating immunomodulatory and antiviral activities of potential pharmaceutical products. Flow cytometry analysis demonstrated significant dengue antigen detection in target cells two days after infection. TNF-alpha, IFN-alpha, IL-6 and IL-10 are produced by in vitro infected monocytes and are significantly detected in cell culture supernatants by multiplex microbead immunoassay. Dexamethasone action was tested for the first time for its modulation in dengue infection, presenting optimistic results in both decreasing cell infection rates and inhibiting TNF-alpha, IFN-alpha and IL-10 production. This model is proposed for novel drug trials yet to be applyed for dengue fever.
Reis, Sônia Regina Nogueira Ignácio; Sampaio, André Luiz Franco; Henriques, Maria das Graças Muller; Gandini, Mariana; Azeredo, Elzinandes Leal; Kubelka, Claire Fernandes
2007-12-01
An important cytokine role in dengue fever pathogenesis has been described. These molecules can be associated with haemorrhagic manifestations, coagulation disorders, hypotension and shock, all symptoms implicated in vascular permeability and disease worsening conditions. Several immunological diseases have been treated by cytokine modulation and dexamethasone is utilized clinically to treat pathologies with inflammatory and autoimmune etiologies. We established an in vitro model with human monocytes infected by dengue virus-2 for evaluating immunomodulatory and antiviral activities of potential pharmaceutical products. Flow cytometry analysis demonstrated significant dengue antigen detection in target cells two days after infection. TNF-alpha, IFN-alpha, IL-6 and IL-10 are produced by in vitro infected monocytes and are significantly detected in cell culture supernatants by multiplex microbead immunoassay. Dexamethasone action was tested for the first time for its modulation in dengue infection, presenting optimistic results in both decreasing cell infection rates and inhibiting TNF-alpha, IFN-alpha and IL-10 production. This model is proposed for novel drug trials yet to be applied for dengue fever.
Hoda M. Eid
2014-01-01
Full Text Available Vaccinium vitis-idaea, commonly known as lingonberry, has been identified among species used by the Cree of Eeyou Istchee of northern Quebec to treat symptoms of diabetes. In a previous study, the ethanol extract of berries of V. vitis-idaea enhanced glucose uptake in C2C12 muscle cells via stimulation of AMP-activated protein kinase (AMPK pathway. The purpose of this study was to examine the effect of plant extract in a dietary mouse model of mild type 2 diabetes. C57BL/6 mice fed a high-fat diet (HFD, ∼35% lipids for 8 weeks that become obese and insulin-resistant (diet-induced obesity, DIO were used. Treatment began by adding V. vitis-idaea extract to HFD at 3 different concentrations (125, 250, and 500 mg/Kg for a subsequent period of 8 weeks (total HFD, 16 weeks. The plant extract significantly decreased glycemia and strongly tended to decrease insulin levels in this model. This was correlated with a significant increase in GLUT4 content and activation of the AMPK and Akt pathways in skeletal muscle. V. vitis-idaea treatment also improved hepatic steatosis by decreasing hepatic triglyceride levels and significantly activated liver AMPK and Akt pathways. The results of the present study confirm that V. vitis-idaea represents a culturally relevant treatment option for Cree diabetics and pave the way to clinical studies.
A Jitter Less VCO Model in PLL for EMTP Simulation
Funaki, Tsuyoshi; Hikihara, Takashi
PLL is used to synchronize the phase of an inverter AC output with that of an utility AC. The dynamic PLL behavior must be accurately simulated for it governs the control performance of an inverter. The VCO part of a PLL conventionally consists of an integrator, which is reset at the instant when it exceeds 2π. A numerical simulation, such as an EMTP simulation, with a fixed time step calculation cannot detect these accurate reset timings. This inconsistency in reset timing induces a phase jitter. The phase error, due to jitter, becomes a severe problem when a large time step is employed to simulate long period phenomena, and the inverter is modeled by the state-space averaging method. This paper proposes a jitter less VCO model for EMTP simulation. The phase jitter of the proposed VCO model is completely suppressed, regardless of the time step length. The improvements are confirmed through EMTP simulations.
Numerical Simulation of the Flow over a Model of the Cavities on a Butterfly Wing
无
1995-01-01
The objective of this paper is to present results of numerical simulations for the flow over cavities modeling the scale structures on the upper surface of a typical butterly wing,The numerical results,obtained using a vortex method,Show that the dynamics of the flow are strongly dependent on the Reynolds number of the flow.The large coherent structures,formed in the cavity of adjoining scales,exhibit a stationary behaviour for low Reynolds number flows,while they exhibit stong dynamics and instabilities for high Reynolds number flows.The numerical resuts are in very good agreement with corresponding experimental results available in the literature.
Teasdale, Normand; Simoneau, Martin; Hudon, Lisa; Germain Robitaille, Mathieu; Moszkowicz, Thierry; Laurendeau, Denis; Bherer, Louis; Duchesne, Simon; Hudon, Carol
2016-01-01
The driving performance of individuals with mild cognitive impairment (MCI) is suboptimal when compared to healthy older adults. It is expected that the driving will worsen with the progression of the cognitive decline and thus, whether or not these individuals should continue to drive is a matter of debate. The aim of the study was to provide support to the claim that individuals with MCI can benefit from a training program and improve their overall driving performance in a driving simulator. Fifteen older drivers with MCI participated in five training sessions in a simulator (over a 21-day period) and in a 6-month recall session. During training, they received automated auditory feedback on their performance when an error was noted about various maneuvers known to be suboptimal in MCI individuals (for instance, weaving, omitting to indicate a lane change, to verify a blind spot, or to engage in a visual search before crossing an intersection). The number of errors was compiled for eight different maneuvers for all sessions. For the initial five sessions, a gradual and significant decrease in the number of errors was observed, indicating learning and safer driving. The level of performance, however, was not maintained at the 6-month recall session. Nevertheless, the initial learning observed opens up possibilities to undertake more regular interventions to maintain driving skills and safe driving in MCI individuals. PMID:28082883
Simulation modeling on the growth of firm's safety management capability
LIU Tie-zhong; LI Zhi-xiang
2008-01-01
Aiming to the deficiency of safety management measure, established simulation model about firm's safety management capability(FSMC) based on organizational learning theory. The system dynamics(SD) method was used, in which level and rate system, variable equation and system structure flow diagram was concluded. Simulation model was verified from two aspects: first, model's sensitivity to variable was tested from the gross of safety investment and the proportion of safety investment; second, variables dependency was checked up from the correlative variable of FSMC and organizational learning. The feasibility of simulation model is verified though these processes.
Simplified Model of Brushless Synchronous Generator for Real Time Simulation
Lopez, M D; Rebollo, E; Blanquez, F R
2015-01-01
This paper presents a simplified model of brushless synchronous machine for saving hardware resources in a real time simulation system. Firstly, a brushless excitation system model is described. Thereafter, the simplified transfer function of an AC exciter and rotating diodes of the brushless excitation system is estimated. Finally, the complete system is simulated, comparing the main generator's voltage with both detailed and simplified excitation systems in several scenarios. These results show the accuracy of the simplified model against the detailed simulation model, resulting on an important hardware resources savings.
Handbook of Real-World Applications in Modeling and Simulation
Sokolowski, John A
2012-01-01
This handbook provides a thorough explanation of modeling and simulation in the most useful, current, and predominant applied areas, such as transportation, homeland security, medicine, operational research, military science, and business modeling. The authors offer a concise look at the key concepts and techniques of modeling and simulation and then discuss how and why the presented domains have become leading applications. The book begins with an introduction of why modeling and simulation is a reliable analysis assessment tool for complex syste
Optical modeling and simulation of thin-film photovoltaic devices
Krc, Janez
2013-01-01
In wafer-based and thin-film photovoltaic (PV) devices, the management of light is a crucial aspect of optimization since trapping sunlight in active parts of PV devices is essential for efficient energy conversions. Optical modeling and simulation enable efficient analysis and optimization of the optical situation in optoelectronic and PV devices. Optical Modeling and Simulation of Thin-Film Photovoltaic Devices provides readers with a thorough guide to performing optical modeling and simulations of thin-film solar cells and PV modules. It offers insight on examples of existing optical models
A study for production simulation model generation system based on data model at a shipyard
Myung-Gi Back
2016-09-01
Full Text Available Simulation technology is a type of shipbuilding product lifecycle management solution used to support production planning or decision-making. Normally, most shipbuilding processes are consisted of job shop production, and the modeling and simulation require professional skills and experience on shipbuilding. For these reasons, many shipbuilding companies have difficulties adapting simulation systems, regardless of the necessity for the technology. In this paper, the data model for shipyard production simulation model generation was defined by analyzing the iterative simulation modeling procedure. The shipyard production simulation data model defined in this study contains the information necessary for the conventional simulation modeling procedure and can serve as a basis for simulation model generation. The efficacy of the developed system was validated by applying it to the simulation model generation of the panel block production line. By implementing the initial simulation model generation process, which was performed in the past with a simulation modeler, the proposed system substantially reduced the modeling time. In addition, by reducing the difficulties posed by different modeler-dependent generation methods, the proposed system makes the standardization of the simulation model quality possible.
Quantifying Stress Using mDFA: Heartbeats Exhibit Stress/Fear/Anxiety in Animal Model and Humans
Toru Yazawa
2015-08-01
Full Text Available Stress has not been fully defined in terms of neuroscience. But, it might be possible to quantify it, like body temperature. The aim of this study was to develop a method to quantify stress, fear and anxiety that has not been accomplished. In the present study, we present a method to quantify them using the biomedical vital information, i.e., the timing of heartbeat. Here electrocardiograms of both animal models and humans were analyzed by modified detrended fluctuation analysis (mDFA, which calculates a scaling exponent (SI from the heartbeat interval time series. The SI was able to numerically distinguish between normal and abnormal hearts. SI values varied with heart conditions, i.e., healthy basal or stressful conditions. This study suggests that mDFA has potential as a practical method for the construction of a device for health management.
Kalin, Jay H; Zhang, Hankun; Gaudrel-Grosay, Sophie; Vistoli, Giulio; Kozikowski, Alan P
2012-03-05
Mercaptoacetamide-based ligands have been designed as a new class of histone deacetylase (HDAC) inhibitors for possible use in the treatment of neurodegenerative diseases. The thiol group of these compounds provides a key binding element for interaction with the catalytic zinc ion, and thus differs from the more typically employed hydroxamic acid based zinc binding groups. Herein we disclose the chemistry and biology of some substituted mercaptoacetamides with the intention of increasing HDAC6 isoform selectivity while maintaining potency similar to their hydroxamic acid analogues. The introduction of a stereocenter α to the thiol group was found to have a considerable impact on HDAC inhibitor potency. These new compounds were also profiled for their therapeutic potential in an in vitro model of stress-induced neuronal injury and were found to act as nontoxic neuroprotective agents. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Soliman, Ahmed M; Fortin, Daniel; Zysman-Colman, Eli; Harvey, Pierre D
2012-04-13
Trans- dichlorobis(tri-n-butylphosphine)platinum(II) reacts with bis(2- phenylpyridinato)-(5,5'-diethynyl-2,2'-bipyridine)iridium(III) hexafluorophosphate to form the luminescent conjugated polymer poly[trans-[(5,5'-ethynyl-2,2'-bipyridine)bis(2- phenylpyridinato)-iridium(III)]bis(tri-n-butylphosphine)platinum(II)] hexafluorophosphate ([Pt]-[Ir])n. Gel permeation chromatography indicates a degree of polymerization of 9 inferring the presence of an oligomer. Comparison of the absorption and emission band positions and their temperature dependence, emission quantum yields, and lifetimes with those for models containing only the [Pt] or the [Ir] units indicates hybrid excited states including features from both chromophores.
Arlt, Matthias J E; Walters, Denise K; Banke, Ingo J; Steinmann, Patrick; Puskas, Gabor J; Bertz, Josefine; Rentsch, Katharina M; Ehrensperger, Felix; Born, Walter; Fuchs, Bruno
2012-09-01
Osteosarcoma (OS) is the most frequent primary bone tumor. Despite multiagent neoadjuvant chemotherapy, patients with metastatic disease have a poor prognosis. Moreover, currently used chemotherapeutics have severe toxic side effects. Thus, novel agents with improved antimetastatic activity and reduced toxicity are needed. Taurolidine, a broad-spectrum antimicrobial, has recently been shown to have antineoplastic properties against a variety of tumors and low systemic toxicity. Consequently, we investigated in our study the antineoplastic potential of taurolidine against OS in two different mouse models. Although both OS cell lines, K7M2 and LM8, were sensitive for the compound in vitro, intraperitoneal application of taurolidine failed to inhibit primary tumor growth. Moreover, it enhanced the metastatic load in both models 1.7- to 20-fold and caused severe liver deformations and up to 40% mortality. Thus, systemic toxicity was further investigated in tumor-free mice histologically, by electron microscopy and by measurements of representative liver enzymes. Taurolidine dose-dependent fibrous thickening of the liver capsule and adhesions and atrophies of the liver lobes were comparable in healthy and tumor-bearing mice. Liver toxicity was further indicated by up to eightfold elevated levels of the liver enzymes alanine transaminase, aspartate transaminase and GLDH in the circulation. Ultrastructural analysis of affected liver tissue showed swollen mitochondria with cristolysis and numerous lipid vacuoles in the cytoplasm of hepatocytes. The findings of our study question the applicability of taurolidine for OS treatment and may suggest the need for caution regarding the widespread clinical use of taurolidine as an antineoplastic agent.
In-vehicle group activity modeling and simulation in sensor-based virtual environment
Shirkhodaie, Amir; Telagamsetti, Durga; Poshtyar, Azin; Chan, Alex; Hu, Shuowen
2016-05-01
Human group activity recognition is a very complex and challenging task, especially for Partially Observable Group Activities (POGA) that occur in confined spaces with limited visual observability and often under severe occultation. In this paper, we present IRIS Virtual Environment Simulation Model (VESM) for the modeling and simulation of dynamic POGA. More specifically, we address sensor-based modeling and simulation of a specific category of POGA, called In-Vehicle Group Activities (IVGA). In VESM, human-alike animated characters, called humanoids, are employed to simulate complex in-vehicle group activities within the confined space of a modeled vehicle. Each articulated humanoid is kinematically modeled with comparable physical attributes and appearances that are linkable to its human counterpart. Each humanoid exhibits harmonious full-body motion - simulating human-like gestures and postures, facial impressions, and hands motions for coordinated dexterity. VESM facilitates the creation of interactive scenarios consisting of multiple humanoids with different personalities and intentions, which are capable of performing complicated human activities within the confined space inside a typical vehicle. In this paper, we demonstrate the efficiency and effectiveness of VESM in terms of its capabilities to seamlessly generate time-synchronized, multi-source, and correlated imagery datasets of IVGA, which are useful for the training and testing of multi-source full-motion video processing and annotation. Furthermore, we demonstrate full-motion video processing of such simulated scenarios under different operational contextual constraints.
NONE
2005-02-15
In connection with the ERP project 'Dynamic modelling of staged gasification processes' a gasification simulator has been constructed. The simulator consists of: a mathematical model of the gasification process developed at Technical University of Denmark, a user interface programme, IGSS, and a communication interface between the two programmes. (BA)
Probabilistic Based Modeling and Simulation Assessment
2010-06-01
but with the head and neck replaced with a high fidelity cervical spine and head model. The occupant models were used to determine the effects of...fidelity cervical spine and head model... vertebrae , including the disks, ligaments and musculature, Figure 6. In total there are 57837 elements with 63713 nodes. A full description of the model
Digital collections and exhibits
Denzer, Juan
2015-01-01
Today's libraries are taking advantage of cutting-edge technologies such as flat panel displays using touch, sound, and hands-free motions to design amazing exhibits using everything from simple computer hardware to advanced technologies such as the Microsoft Kinect. Libraries of all types are striving to add new interactive experiences for their patrons through exciting digital exhibits, both online and off. Digital Collections and Exhibits takes away the mystery of designing stunning digital exhibits to spotlight library trea
Model and simulation of Krause model in dynamic open network
Zhu, Meixia; Xie, Guangqiang
2017-08-01
The construction of the concept of evolution is an effective way to reveal the formation of group consensus. This study is based on the modeling paradigm of the HK model (Hegsekmann-Krause). This paper analyzes the evolution of multi - agent opinion in dynamic open networks with member mobility. The results of the simulation show that when the number of agents is constant, the interval distribution of the initial distribution will affect the number of the final view, The greater the distribution of opinions, the more the number of views formed eventually; The trust threshold has a decisive effect on the number of views, and there is a negative correlation between the trust threshold and the number of opinions clusters. The higher the connectivity of the initial activity group, the more easily the subjective opinion in the evolution of opinion to achieve rapid convergence. The more open the network is more conducive to the unity of view, increase and reduce the number of agents will not affect the consistency of the group effect, but not conducive to stability.
Modeling and simulation of membrane process
Staszak, Maciej
2017-06-01
The article presents the different approaches to polymer membrane mathematical modeling. Traditional models based on experimental physicochemical correlations and balance models are presented in the first part. Quantum and molecular mechanics models are presented as they are more popular for polymer membranes in fuel cells. The initial part is enclosed by neural network models which found their use for different types of processes in polymer membranes. The second part is devoted to models of fluid dynamics. The computational fluid dynamics technique can be divided into solving of Navier-Stokes equations and into Boltzmann lattice models. Both approaches are presented focusing on membrane processes.
Application of simulation modeling to lipid peroxidation processes.
Tappel, A L; Tappel, A A; Fraga, C G
1989-01-01
A quantitative simulation model was developed that utilized present knowledge of lipid peroxidation in biological systems. The simulation model incorporated the following features: peroxidizability of polyunsaturated lipids, activation of inducers and their initiation of lipid peroxidation, concurrent autoxidation, inhibition of lipid peroxidation by vitamin E, reduction of some of the hydroperoxides by glutathione peroxidase, and formation of thiobarbituric acid-reactive substances. Simulation calculations were done using a computer spreadsheet program. When the simulation program was applied to tissue slice and microsomal peroxidizing systems, the results of the stimulation were in agreement with the experimental data.
A View on Future Building System Modeling and Simulation
Wetter, Michael
2011-04-01
This chapter presents what a future environment for building system modeling and simulation may look like. As buildings continue to require increased performance and better comfort, their energy and control systems are becoming more integrated and complex. We therefore focus in this chapter on the modeling, simulation and analysis of building energy and control systems. Such systems can be classified as heterogeneous systems because they involve multiple domains, such as thermodynamics, fluid dynamics, heat and mass transfer, electrical systems, control systems and communication systems. Also, they typically involve multiple temporal and spatial scales, and their evolution can be described by coupled differential equations, discrete equations and events. Modeling and simulating such systems requires a higher level of abstraction and modularisation to manage the increased complexity compared to what is used in today's building simulation programs. Therefore, the trend towards more integrated building systems is likely to be a driving force for changing the status quo of today's building simulation programs. Thischapter discusses evolving modeling requirements and outlines a path toward a future environment for modeling and simulation of heterogeneous building systems.A range of topics that would require many additional pages of discussion has been omitted. Examples include computational fluid dynamics for air and particle flow in and around buildings, people movement, daylight simulation, uncertainty propagation and optimisation methods for building design and controls. For different discussions and perspectives on the future of building modeling and simulation, we refer to Sahlin (2000), Augenbroe (2001) and Malkawi and Augenbroe (2004).
Reducing outpatient waiting time: a simulation modeling approach.
Aeenparast, Afsoon; Tabibi, Seyed Jamaleddin; Shahanaghi, Kamran; Aryanejhad, Mir Bahador
2013-09-01
The objective of this study was to provide a model for reducing outpatient waiting time by using simulation. A simulation model was constructed by using the data of arrival time, service time and flow of 357 patients referred to orthopedic clinic of a general teaching hospital in Tehran. The simulation model was validated before constructing different scenarios. In this study 10 scenarios were presented for reducing outpatient waiting time. Patients waiting time was divided into three levels regarding their physicians. These waiting times for all scenarios were computed by simulation model. According to the final scores the 9th scenario was selected as the best way for reducing outpatient's waiting time. Using the simulation as a decision making tool helps us to decide how we can reduce outpatient's waiting time. Comparison of outputs of this scenario and the based- case scenario in simulation model shows that combining physician's work time changing with patient's admission time changing (scenario 9) would reduce patient waiting time about 73.09%. Due to dynamic and complex nature of healthcare systems, the application of simulation for the planning, modeling and analysis of these systems has lagged behind traditional manufacturing practices. Rapid growth in health care system expenditures, technology and competition has increased the complexity of health care systems. Simulation is a useful tool for decision making in complex and probable systems.
Calibration of the simulation model of the VINCY cyclotron magnet
Ćirković Saša
2002-01-01
Full Text Available The MERMAID program will be used to isochronise the nominal magnetic field of the VINCY Cyclotron. This program simulates the response, i. e. calculates the magnetic field, of a previously defined model of a magnet. The accuracy of 3D field calculation depends on the density of the grid points in the simulation model grid. The size of the VINCY Cyclotron and the maximum number of grid points in the XY plane limited by MERMAID define the maximumobtainable accuracy of field calculations. Comparisons of the field simulated with maximum obtainable accuracy with the magnetic field measured in the first phase of the VINCY Cyclotron magnetic field measurements campaign has shown that the difference between these two fields is not as small as required. Further decrease of the difference between these fields is obtained by the simulation model calibration, i. e. by adjusting the current through the main coils in the simulation model.
Calibration of the simulation model of the Vincy cyclotron magnet
Cirkovic, S; Vorozhtsov, A S; Vorozhtsov, S B
2002-01-01
The MERMAID program will be used to isochronise the nominal magnetic field of the VINCY Cyclotron. This program simulates the response, i. e. calculates the magnetic field, of a previously defined model of a magnet. The accuracy of 3D field calculation depends on the density of the grid points in the simulation model grid. The size of the VINCY Cyclotron and the maximum number of grid points in the XY plane limited by MERMAID define the maximum obtainable accuracy of field calculations. Comparisons of the field simulated with maximum obtainable accuracy with the magnetic field measured in the first phase of the VINCY Cyclotron magnetic field measurements campaign has shown that the difference between these two fields is not as small as required. Further decrease of the difference between these fields is obtained by the simulation model calibration, i. e. by adjusting the current through the main coils in the simulation model.
Spin-dynamics simulations of the antiferromagnetic triangular XY model*
Nho, Kwangsik; Landau, D. P.
2002-03-01
Using Monte Carlo and spin-dynamics methods, we have simulated the dynamic behavior of the classical, antiferromagnetic XY model on a triangular lattice. The temporal evolutions of spin configurations were obtained by solving numerically the coupled equations of motion for each spin using fourth-order Suzuki-Trotter decompositions of exponential operators. From space-and time-displaced spin-spin correlation functions and their space-time Fourier transforms we obtained the dynamic structure factor S(q,w) for momentum q and frequency w. Below T_c, where long-range order appears in the staggered chirality[1], S(q,w) exhibits very strong and sharp spin-wave peaks in the in-plane-component S^xx. We also observe two-spin-wave peaks at low w and an almost dispersionless domain-wall peak at high w. Above T_c, a weak spin-wave peak persists but the domain-wall peak disappears for all q. We have calculated the dispersion relation and the linewidth of the spin-wave peak in S^xx by fitting the line shape to simple Lorentzians. *Supported by NSF [1] D.H. Lee, J.D. Joannopoulos, J.W. Negele, and D.P. Landau, Phys. Rev. Lett. 52, 433 (1984)
MODELING OF HIGH STORAGE SHEET DEPOT WITH PLANT SIMULATION
Andrzej Jardzioch
2013-03-01
Full Text Available Manufacturing processes are becoming increasingly automated. Introduction of innovative solutions often necessitate processing very large number of signals from various devices. Correctness tests of the components configuration becomes a compiled operation requiring vast expenditure of time and knowledge. The models may be a mathematical reflection of the actual object. Many actions can be computer-assisted to varying degree. One example is construction of simulation models. These can also be simulation models developed in advanced software. The stages of creating a model may be purely random. This paper aims at a closer analysis of the simulation model based on the high storage sheet depot modeling using Plant Simulation software. The results of analysis can be used for optimization, but this stage is a separate issue.
A framework for the calibration of social simulation models
Ciampaglia, Giovanni Luca
2013-01-01
Simulation with agent-based models is increasingly used in the study of complex socio-technical systems and in social simulation in general. This paradigm offers a number of attractive features, namely the possibility of modeling emergent phenomena within large populations. As a consequence, often the quantity in need of calibration may be a distribution over the population whose relation with the parameters of the model is analytically intractable. Nevertheless, we can simulate. In this paper we present a simulation-based framework for the calibration of agent-based models with distributional output based on indirect inference. We illustrate our method step by step on a model of norm emergence in an online community of peer production, using data from three large Wikipedia communities. Model fit and diagnostics are discussed.
Mangum, Joshua E.; Hardee, Justin P.; Fix, Dennis K.; Puppa, Melissa J.; Elkes, Johnathon; Altomare, Diego; Bykhovskaya, Yelena; Campagna, Dean R.; Schmidt, Paul J.; Sendamarai, Anoop K.; Lidov, Hart G. W.; Barlow, Shayne C.; Fischel-Ghodsian, Nathan; Fleming, Mark D.; Carson, James A.; Patton, Jeffrey R.
2016-01-01
Mitochondrial myopathy with lactic acidosis and sideroblastic anemia (MLASA) is an oxidative phosphorylation disorder, with primary clinical manifestations of myopathic exercise intolerance and a macrocytic sideroblastic anemia. One cause of MLASA is recessive mutations in PUS1, which encodes pseudouridine (Ψ) synthase 1 (Pus1p). Here we describe a mouse model of MLASA due to mutations in PUS1. As expected, certain Ψ modifications were missing in cytoplasmic and mitochondrial tRNAs from Pus1−/− animals. Pus1−/− mice were born at the expected Mendelian frequency and were non-dysmorphic. At 14 weeks the mutants displayed reduced exercise capacity. Examination of tibialis anterior (TA) muscle morphology and histochemistry demonstrated an increase in the cross sectional area and proportion of myosin heavy chain (MHC) IIB and low succinate dehydrogenase (SDH) expressing myofibers, without a change in the size of MHC IIA positive or high SDH myofibers. Cytochrome c oxidase activity was significantly reduced in extracts from red gastrocnemius muscle from Pus1−/− mice. Transmission electron microscopy on red gastrocnemius muscle demonstrated that Pus1−/− mice also had lower intermyofibrillar mitochondrial density and smaller mitochondria. Collectively, these results suggest that alterations in muscle metabolism related to mitochondrial content and oxidative capacity may account for the reduced exercise capacity in Pus1−/− mice. PMID:27197761
2004-01-01
EARLY this year an exhibition on the ancient civilization of Etruria was held at the Beijing-based China Millennium Monument.The theme of the exhibition was Etruscan Culture and on show were the most representative cultural and historical relics of this ancient civilization unearthed in the past 20 years. The 349 exhibits from various
Vick, Randy M.
2011-01-01
This article discusses ethical questions raised by an exhibition of work by an artist with a history of mental illness and the exhibition's relevance to art therapy and “outsider art” discourse on the subject. Considerations for how such an exhibit could be handled had the circumstances included an art therapist and art therapy client are…
NATO Modelling and Simulation Standards Profile
Huiskamp, W.; Igarza, J.L.; Voiculet, A.
2012-01-01
Open and common standards are essential enablers for simulation interoperability and re-use. This includes: Technical architecture standards - e.g. HLA - the High Level Architecture, Data interchange standards - e.g. SEDRIS - Synthetic Environment Data Representation and Interchange
Motion perception modelling in flight simulation
Groen, E.L.; Hosman, R.J.A.W.; Bos, J.E.; Dominicus, J.W.
2004-01-01
Motion cueing algorithms are indispensable to transform aircraft motions into simulator motions. Usually, such algorithms apply to the whole flight envelope. Since a motion base should stay within its six degrees of freedom workspace, the parameter settings necessarily involve concessions, which may
Cognitive model supported tactical training simulation
Doesburg, W.A. van; Bosch, K. van den
2005-01-01
Simulation-based tactical training can be made more effective by using cognitive software agents to play key roles (e.g. team mate, adversaries, instructor). Due to the dynamic and complex nature of military tactics, it is hard to create agents that behave realistically and support the training lead
System Simulation Modeling: A Case Study Illustration of the Model Development Life Cycle
Janice K. Wiedenbeck; D. Earl Kline
1994-01-01
Systems simulation modeling techniques offer a method of representing the individual elements of a manufacturing system and their interactions. By developing and experimenting with simulation models, one can obtain a better understanding of the overall physical system. Forest products industries are beginning to understand the importance of simulation modeling to help...
Plant growth simulation for landscape scale hydrologic modeling
Landscape scale hydrologic models can be improved by incorporating realistic, process-oriented plant models for simulating crops, grasses, and woody species. The objective of this project was to present some approaches for plant modeling applicable to hydrologic models like SWAT that can affect the...
A transient model to simulate HTPEM fuel cell impedance spectra
Vang, Jakob Rabjerg; Andreasen, Søren Juhl; Kær, Søren Knudsen
2012-01-01
This paper presents a spatially resolved transient fuel cell model applied to the simulation of high temperature PEM fuel cell impedance spectra. The model is developed using a 2D finite volume method approach. The model is resolved along the channel and across the membrane. The model considers...
Discrete event simulation: Modeling simultaneous complications and outcomes
Quik, E.H.; Feenstra, T.L.; Krabbe, P.F.M.
2012-01-01
OBJECTIVES: To present an effective and elegant model approach to deal with specific characteristics of complex modeling. METHODS: A discrete event simulation (DES) model with multiple complications and multiple outcomes that each can occur simultaneously was developed. In this DES model parameters,
Geometry model construction in infrared image theory simulation of buildings
谢鸣; 李玉秀; 徐辉; 谈和平
2004-01-01
Geometric model construction is the basis of infrared image theory simulation. Taking the construction of the geometric model of one building in Harbin as an example, this paper analyzes the theoretical groundings of simplification and principles of geometric model construction of buildings. It then discusses some particular treatment methods in calculating the radiation transfer coefficient in geometric model construction using the Monte Carlo Method.
Olsen, Martin; Troldborg, Lars; Boegh, Eva
2008-01-01
The consequences of using simulated discharge from a conventional hydrological model as input in stream physical habitat modelling was investigated using output from the Danish national hydrological model and a physical habitat model of three small streams. It was found that low flow simulation...... errors could have large impact on simulation of physical habitat conditions. If these two models are to be used to assess groundwater abstraction impact on physical habitat conditions the hydrological model should be tuned to the purpose...
Olsen, Martin; Troldborg, Lars; Boegh, Eva;
2008-01-01
The consequences of using simulated discharge from a conventional hydrological model as input in stream physical habitat modelling was investigated using output from the Danish national hydrological model and a physical habitat model of three small streams. It was found that low flow simulation...... errors could have large impact on simulation of physical habitat conditions. If these two models are to be used to assess groundwater abstraction impact on physical habitat conditions the hydrological model should be tuned to the purpose...
Air Gun Launch Simulation Modeling and Finite Element Model Sensitivity Analysis
2006-01-01
Air Gun Launch Simulation Modeling and Finite Element Model Sensitivity Analysis by Mostafiz R. Chowdhury and Ala Tabiei ARL-TR-3703...Adelphi, MD 20783-1145 ARL-TR-3703 January 2006 Air Gun Launch Simulation Modeling and Finite Element Model Sensitivity Analysis...GRANT NUMBER 4. TITLE AND SUBTITLE Air Gun Launch Simulation Modeling and Finite Element Model Sensitivity Analysis 5c. PROGRAM
Zvaritch, Elena; MacLennan, David H., E-mail: david.maclennan@utoronto.ca
2015-04-24
Muscle spindles from the hind limb muscles of adult Ryr1{sup I4895T/wt} (IT/+) mice exhibit severe structural abnormalities. Up to 85% of the spindles are separated from skeletal muscle fascicles by a thick layer of connective tissue. Many intrafusal fibers exhibit degeneration, with Z-line streaming, compaction and collapse of myofibrillar bundles, mitochondrial clumping, nuclear shrinkage and pyknosis. The lesions resemble cores observed in the extrafusal myofibers of this animal model and of core myopathy patients. Spindle abnormalities precede those in extrafusal fibers, indicating that they are a primary pathological feature in this murine Ryr1-related core myopathy. Muscle spindle involvement, if confirmed for human core myopathy patients, would provide an explanation for an array of devastating clinical features characteristic of these diseases and provide novel insights into the pathology of RYR1-related myopathies. - Highlights: • Muscle spindles exhibit structural abnormalities in a mouse model of core myopathy. • Myofibrillar collapse and mitochondrial clumping is observed in intrafusal fibers. • Myofibrillar degeneration follows a pattern similar to core formation in extrafusal myofibers. • Muscle spindle abnormalities are a part of the pathological phenotype in the mouse model of core myopathy. • Direct involvement of muscle spindles in the pathology of human RYR1-related myopathies is proposed.
Colon-available raspberry polyphenols exhibit anti-cancer effects on in vitro models of colon cancer
McDougall Gordon
2007-01-01
Full Text Available Abstract Background There is a probable association between consumption of fruit and vegetables and reduced risk of cancer, particularly cancer of the digestive tract. This anti-cancer activity has been attributed in part to anti-oxidants present in these foods. Raspberries in particular are a rich source of the anti-oxidant compounds, such as polyphenols, anthocyanins and ellagitannins. Methods A "colon-available" raspberry extract (CARE was prepared that contained phytochemicals surviving a digestion procedure that mimicked the physiochemical conditions of the upper gastrointestinal tract. The polyphenolic-rich extract was assessed for anti-cancer properties in a series of in vitro systems that model important stages of colon carcinogenesis, initiation, promotion and invasion. Results The phytochemical composition of CARE was monitored using liquid chromatography mass spectrometry. The colon-available raspberry extract was reduced in anthocyanins and ellagitannins compared to the original raspberry juice but enriched in other polyphenols and polyphenol breakdown products that were more stable to gastrointestinal digestion. Initiation – CARE caused significant protective effects against DNA damage induced by hydrogen peroxide in HT29 colon cancer cells measured using single cell microgelelectrophoresis. Promotion – CARE significantly decreased the population of HT29 cells in the G1 phase of the cell cycle, effectively reducing the number of cells entering the cell cycle. However, CARE had no effect on epithelial integrity (barrier function assessed by recording the trans-epithelial resistance (TER of CACO-2 cell monolayers. Invasion – CARE caused significant inhibition of HT115 colon cancer cell invasion using the matrigel invasion assay. Conclusion The results indicate that raspberry phytochemicals likely to reach the colon are capable of inhibiting several important stages in colon carcinogenesis in vitro.
Heterogeneous Speed Profiles in Discrete Models for Pedestrian Simulation
Bandini, Stefania; Crociani, Luca; Vizzari, Giuseppe
2014-01-01
Discrete pedestrian simulation models are viable alternatives to particle based approaches based on a continuous spatial representation. The effects of discretisation, however, also imply some difficulties in modelling certain phenomena that can be observed in reality. This paper focuses on the possibility to manage heterogeneity in the walking speed of the simulated population of pedestrians by modifying an existing multi-agent model extending the floor field approach. Whereas some discrete ...
Verilog-A modeling of SPAD for circuit simulations
Yang, Hong-jiao; Jin, Xiang-liang; Zhou, Xiao-ya; Chen, Chang-ping; Luo, Jun
2013-08-01
A behavior mode for simulating single-photon avalanche diodes is presented. The model is developed using Verilog-A description language. The derived model is able to describe the static, the dynamic behavior, the triggering, the self-sustaining and the self-quenching processes, and it also correctly characterizes the reverse current-voltage curve. Simulation results confirmed the validity of the proposed model.
Integrated simulation and modeling capability for alternate magnetic fusion concepts
Cohen, B. I.; Hooper, E.B.; Jarboe, T. R.; LoDestro, L. L.; Pearlstein, L. D.; Prager, S. C.; Sarff, J. S.
1998-11-03
This document summarizes a strategic study addressing the development of a comprehensive modeling and simulation capability for magnetic fusion experiments with particular emphasis on devices that are alternatives to the mainline tokamak device. A code development project in this area supports two defined strategic thrust areas in the Magnetic Fusion Energy Program: (1) comprehensive simulation and modeling of magnetic fusion experiments and (2) development, operation, and modeling of magnetic fusion alternate- concept experiment
Jeannin-Girardon, Anne; Ballet, Pascal; Rodin, Vincent
2015-01-01
The complexity of biological tissue morphogenesis makes in silico simulations of such system very interesting in order to gain a better understanding of the underlying mechanisms ruling the development of multicellular tissues. This complexity is mainly due to two elements: firstly, biological tissues comprise a large amount of cells; secondly, these cells exhibit complex interactions and behaviors. To address these two issues, we propose two tools: the first one is a virtual cell model that comprise two main elements: firstly, a mechanical structure (membrane, cytoskeleton, and cortex) and secondly, the main behaviors exhibited by biological cells, i.e., mitosis, growth, differentiation, molecule consumption, and production as well as the consideration of the physical constraints issued from the environment. An artificial chemistry is also included in the model. This virtual cell model is coupled to an agent-based formalism. The second tool is a simulator that relies on the OpenCL framework. It allows efficient parallel simulations on heterogenous devices such as micro-processors or graphics processors. We present two case studies validating the implementation of our model in our simulator: cellular proliferation controlled by cell signalling and limb growth in a virtual organism.
Methodology for characterizing modeling and discretization uncertainties in computational simulation
ALVIN,KENNETH F.; OBERKAMPF,WILLIAM L.; RUTHERFORD,BRIAN M.; DIEGERT,KATHLEEN V.
2000-03-01
This research effort focuses on methodology for quantifying the effects of model uncertainty and discretization error on computational modeling and simulation. The work is directed towards developing methodologies which treat model form assumptions within an overall framework for uncertainty quantification, for the purpose of developing estimates of total prediction uncertainty. The present effort consists of work in three areas: framework development for sources of uncertainty and error in the modeling and simulation process which impact model structure; model uncertainty assessment and propagation through Bayesian inference methods; and discretization error estimation within the context of non-deterministic analysis.
Four Order Electrostatic Discharge Circuit Model and its Simulation
Xiaodong Wang
2012-12-01
Full Text Available According to the international electrotechnical commission issued IEC61000-4-2 test standard, through the electrostatic discharge current waveform characteristics analysis and numerical experiment method, and construct a new ESD current expression. Using Laplasse transform, established the ESD system mathematical model. According to the mathematical model, construction of passive four order ESD system circuit model and active four order ESD system circuit model, and simulation. The simulation results meet the IEC61000-4-2 standard, and verify the consistency of the ESD current expression, the mathematical model and the circuit model.
Monte Carlo simulation of Prussian blue analogs described by Heisenberg ternary alloy model
Yüksel, Yusuf
2015-11-01
Within the framework of Monte Carlo simulation technique, we simulate magnetic behavior of Prussian blue analogs based on Heisenberg ternary alloy model. We present phase diagrams in various parameter spaces, and we compare some of our results with those based on Ising counterparts. We clarify the variations of transition temperature and compensation phenomenon with mixing ratio of magnetic ions, exchange interactions, and exchange anisotropy in the present ferro-ferrimagnetic Heisenberg system. According to our results, thermal variation of the total magnetization curves may exhibit N, L, P, Q, R type behaviors based on the Néel classification scheme.
Optimization of Operations Resources via Discrete Event Simulation Modeling
Joshi, B.; Morris, D.; White, N.; Unal, R.
1996-01-01
The resource levels required for operation and support of reusable launch vehicles are typically defined through discrete event simulation modeling. Minimizing these resources constitutes an optimization problem involving discrete variables and simulation. Conventional approaches to solve such optimization problems involving integer valued decision variables are the pattern search and statistical methods. However, in a simulation environment that is characterized by search spaces of unknown topology and stochastic measures, these optimization approaches often prove inadequate. In this paper, we have explored the applicability of genetic algorithms to the simulation domain. Genetic algorithms provide a robust search strategy that does not require continuity and differentiability of the problem domain. The genetic algorithm successfully minimized the operation and support activities for a space vehicle, through a discrete event simulation model. The practical issues associated with simulation optimization, such as stochastic variables and constraints, were also taken into consideration.
Semiempirical model for nanoscale device simulations
Stokbro, Kurt; Petersen, Dan Erik; Smidstrup, Søren;
2010-01-01
We present a semiempirical model for calculating electron transport in atomic-scale devices. The model is an extension of the extended Hückel method with a self-consistent Hartree potential that models the effect of an external bias and corresponding charge rearrangements in the device. It is als...
A universal simulator for ecological models
Holst, Niels
2013-01-01
Software design is an often neglected issue in ecological models, even though bad software design often becomes a hindrance for re-using, sharing and even grasping an ecological model. In this paper, the methodology of agile software design was applied to the domain of ecological models. Thus...
Modeling Physics with Easy Java Simulations
Christian, Wolfgang; Esquembre, Francisco
2007-01-01
Modeling has been shown to correct weaknesses of traditional instruction by engaging students in the design of physical models to describe, explain, and predict phenomena. Although the modeling method can be used without computers, the use of computers allows students to study problems that are difficult and time consuming, to visualize their…
Coastal zone simulations with variational Boussinesq modelling
Adytia, Didit
2012-01-01
The main challenge in deriving a Boussinesq model for water wave is to model accurately the dispersion and nonlinearity of waves. The dispersion is a depth-dependent relation between the wave speed and the wavelength. A Boussinesq-type model can be derived from the so-called variational principle
Overnight Index Rate: Model, calibration and simulation
Olga Yashkir; Yuri Yashkir
2014-01-01
In this study, the extended Overnight Index Rate (OIR) model is presented. The fitting function for the probability distribution of the OIR daily returns is based on three different Gaussian distributions which provide modelling of the narrow central peak and the wide fat-tailed component. The calibration algorithm for the model is developed and investigated using the historical OIR data.
Overnight Index Rate: Model, calibration and simulation
Olga Yashkir
2014-12-01
Full Text Available In this study, the extended Overnight Index Rate (OIR model is presented. The fitting function for the probability distribution of the OIR daily returns is based on three different Gaussian distributions which provide modelling of the narrow central peak and the wide fat-tailed component. The calibration algorithm for the model is developed and investigated using the historical OIR data.
Overnight Index Rate: Model, Calibration, and Simulation
Olga Yashkir; Yuri Yashkir
2013-01-01
In this study, the extended Overnight Index Rate (OIR) model is presented. The fitting function for the probability distribution of the OIR daily returns is based on three different Gaussian distributions which provide modelling of the narrow central peak and the wide fat-tailed component. The calibration algorithm for the model is developed and investigated using the historical OIR data.
The Effects of Model Resolution on the Simulation of Regional Climate Extreme Events
无
2007-01-01
The fifth-generation Pennsylvania State University/NCAR Mesoscale Model Version 3 (MM5V3) was used to simulate extreme heavy rainfall events over the Yangtze River Basin in June 1999. The effects of model's horizontal and vertical resolution on the extreme climate events were investigated in detail. In principle, the model was able to characterize the spatial distribution of monthly heavy precipitation. The results indicated that the increase in horizontal resolution could reduce the bias of the modeled heavy rain and reasonably simulate the change of daily precipitation during the study period. A finer vertical resolution led to obviously improve rainfall simulations with smaller biases, and hence, better resolve heavy rainfall events. The increase in both horizontal and vertical resolution could produce better predictions of heavy rainfall events. Not only the rainfall simulation altered in the cases of different horizontal and vertical grid spacing, but also other meteorological fields demonstrated diverse variations in terms of resolution change in the model. An evident improvement in the simulated sea level pressure resulted from the increase of horizontal resolution, but the simulation was insensitive to vertical grid spacing. The increase in vertical resolution could enhance the simulation of surface temperature as well as atmospheric circulation at low levels, while the simulation of circulation at middle and upper levels were found to be much less dependent on changing resolution. In addition, cumulus parameterization schemes showed high sensitivity to horizontal resolution. Different convective schemes exhibited large discrepancies in rainfall simulations with regards to changing resolution. The percentage of convective precipitation in the Grell scheme increased with increasing horizontal resolution. In contrast, the Kain-Fritsch scheme caused a reduced ratio of convective precipitation to total rainfall accumulations corresponding to increasing
Modeling neutron guides using Monte Carlo simulations
Wang, D Q; Crow, M L; Wang, X L; Lee, W T; Hubbard, C R
2002-01-01
Four neutron guide geometries, straight, converging, diverging and curved, were characterized using Monte Carlo ray-tracing simulations. The main areas of interest are the transmission of the guides at various neutron energies and the intrinsic time-of-flight (TOF) peak broadening. Use of a delta-function time pulse from a uniform Lambert neutron source allows one to quantitatively simulate the effect of guides' geometry on the TOF peak broadening. With a converging guide, the intensity and the beam divergence increases while the TOF peak width decreases compared with that of a straight guide. By contrast, use of a diverging guide decreases the intensity and the beam divergence, and broadens the width (in TOF) of the transmitted neutron pulse.
ISM Simulations: An Overview of Models
de Avillez, M A; Asgekar, A; Spitoni, E
2013-01-01
Until recently the dynamical evolution of the interstellar medium (ISM) was simulated using collisional ionization equilibrium (CIE) conditions. However, the ISM is a dynamical system, in which the plasma is naturally driven out of equilibrium due to atomic and dynamic processes operating on different timescales. A step forward in the field comprises a multi-fluid approach taking into account the joint thermal and dynamical evolutions of the ISM gas.
Impact of reactive settler models on simulated WWTP performance.
Gernaey, K V; Jeppsson, U; Batstone, D J; Ingildsen, P
2006-01-01
Including a reactive settler model in a wastewater treatment plant model allows representation of the biological reactions taking place in the sludge blanket in the settler, something that is neglected in many simulation studies. The idea of including a reactive settler model is investigated for an ASM1 case study. Simulations with a whole plant model including the non-reactive Takács settler model are used as a reference, and are compared to simulation results considering two reactive settler models. The first is a return sludge model block removing oxygen and a user-defined fraction of nitrate, combined with a non-reactive Takács settler. The second is a fully reactive ASM1 Takács settler model. Simulations with the ASM1 reactive settler model predicted a 15.3% and 7.4% improvement of the simulated N removal performance, for constant (steady-state) and dynamic influent conditions respectively. The oxygen/nitrate return sludge model block predicts a 10% improvement of N removal performance under dynamic conditions, and might be the better modelling option for ASM1 plants: it is computationally more efficient and it will not overrate the importance of decay processes in the settler.
Statistical Modeling of Large-Scale Scientific Simulation Data
Eliassi-Rad, T; Baldwin, C; Abdulla, G; Critchlow, T
2003-11-15
With the advent of massively parallel computer systems, scientists are now able to simulate complex phenomena (e.g., explosions of a stars). Such scientific simulations typically generate large-scale data sets over the spatio-temporal space. Unfortunately, the sheer sizes of the generated data sets make efficient exploration of them impossible. Constructing queriable statistical models is an essential step in helping scientists glean new insight from their computer simulations. We define queriable statistical models to be descriptive statistics that (1) summarize and describe the data within a user-defined modeling error, and (2) are able to answer complex range-based queries over the spatiotemporal dimensions. In this chapter, we describe systems that build queriable statistical models for large-scale scientific simulation data sets. In particular, we present our Ad-hoc Queries for Simulation (AQSim) infrastructure, which reduces the data storage requirements and query access times by (1) creating and storing queriable statistical models of the data at multiple resolutions, and (2) evaluating queries on these models of the data instead of the entire data set. Within AQSim, we focus on three simple but effective statistical modeling techniques. AQSim's first modeling technique (called univariate mean modeler) computes the ''true'' (unbiased) mean of systematic partitions of the data. AQSim's second statistical modeling technique (called univariate goodness-of-fit modeler) uses the Andersen-Darling goodness-of-fit method on systematic partitions of the data. Finally, AQSim's third statistical modeling technique (called multivariate clusterer) utilizes the cosine similarity measure to cluster the data into similar groups. Our experimental evaluations on several scientific simulation data sets illustrate the value of using these statistical models on large-scale simulation data sets.
Modeling and Real-Time Simulation of UPFC
Kimura, Misao; Takahashi, Choei; Kishibe, Hideto; Miyazaki, Yasuyuki; Noro, Yasuhiro; Iio, Naotaka
We have developed a digital real time simulator of Power Electronics Controllers, so called FACTS (Flexible AC Transmission Systems) Controllers and/or Custom Power by using MATLABTM/SIMULINKTM and dSPACETM System. This paper describes the modeling and the calculation accuracy of a UPFC (Unified Power Flow Controller) model. Hence the developed simulator operates at a large time step, in order to improve simulation accuracy, a correction processing of the switching delay is implemented into the UPFC model. Calculation accuracy of the real time UPFC model is the same level as EMTDCTM results. We confirm stable operation of the developed UPFC model with connecting a commercial real time digital simulator (RTDSTM).
Modelling and simulation of superalloys. Book of abstracts
Rogal, Jutta; Hammerschmidt, Thomas; Drautz, Ralf (eds.)
2014-07-01
Superalloys are multi-component materials with complex microstructures that offer unique properties for high-temperature applications. The complexity of the superalloy materials makes it particularly challenging to obtain fundamental insight into their behaviour from the atomic structure to turbine blades. Recent advances in modelling and simulation of superalloys contribute to a better understanding and prediction of materials properties and therefore offer guidance for the development of new alloys. This workshop will give an overview of recent progress in modelling and simulation of materials for superalloys, with a focus on single crystal Ni-base and Co-base alloys. Topics will include electronic structure methods, atomistic simulations, microstructure modelling and modelling of microstructural evolution, solidification and process simulation as well as the modelling of phase stability and thermodynamics.
A dynamic skull model for simulation of cerebral cortex folding.
Chen, Hanbo; Guo, Lei; Nie, Jingxin; Zhang, Tuo; Hu, Xintao; Liu, Tianming
2010-01-01
The mechanisms of human cerebral cortex folding and their interactions during brain development are largely unknown, partly due to the difficulties in biological experiments and data acquisition for the developing fetus brain. Computational modeling and simulation provide a novel approach to the understanding of cortex folding processes in normal or aberrant neurodevelopment. Based on our recently developed computational model of the cerebral cortex folding using neuronal growth model and mechanical skull constraint, this paper presents a computational dynamic model of the brain skull that regulates the cortical folding simulation. Our simulation results show that the dynamic skull model is more biologically realistic and significantly improves our cortical folding simulation results. This work provides further computational support to the hypothesis that skull is an important regulator of cortical folding.
Automatic identification of model reductions for discrete stochastic simulation
Wu, Sheng; Fu, Jin; Li, Hong; Petzold, Linda
2012-07-01
Multiple time scales in cellular chemical reaction systems present a challenge for the efficiency of stochastic simulation. Numerous model reductions have been proposed to accelerate the simulation of chemically reacting systems by exploiting time scale separation. However, these are often identified and deployed manually, requiring expert knowledge. This is time-consuming, prone to error, and opportunities for model reduction may be missed, particularly for large models. We propose an automatic model analysis algorithm using an adaptively weighted Petri net to dynamically identify opportunities for model reductions for both the stochastic simulation algorithm and tau-leaping simulation, with no requirement of expert knowledge input. Results are presented to demonstrate the utility and effectiveness of this approach.
Adaptive deployment of model reductions for tau-leaping simulation.
Wu, Sheng; Fu, Jin; Petzold, Linda R
2015-05-28
Multiple time scales in cellular chemical reaction systems often render the tau-leaping algorithm inefficient. Various model reductions have been proposed to accelerate tau-leaping simulations. However, these are often identified and deployed manually, requiring expert knowledge. This is time-consuming and prone to error. In previous work, we proposed a methodology for automatic identification and validation of model reduction opportunities for tau-leaping simulation. Here, we show how the model reductions can be automatically and adaptively deployed during the time course of a simulation. For multiscale systems, this can result in substantial speedups.
An Integrated Simulation Tool for Modeling the Human Circulatory System
Asami, Ken'ichi; Kitamura, Tadashi
This paper presents an integrated simulation of the circulatory system in physiological movement. The large circulatory system model includes principal organs and functional units in modules in which comprehensive physiological changes such as nerve reflexes, temperature regulation, acid/base balance, O2/CO2 balance, and exercise are simulated. A beat-by-beat heart model, in which the corresponding electrical circuit problems are solved by a numerical analytic method, enables calculation of pulsatile blood flow to the major organs. The integration of different perspectives on physiological changes makes this simulation model applicable for the microscopic evaluation of blood flow under various conditions in the human body.
Microbial Growth Modeling and Simulation Based on Cellular Automata
Hong Men
2013-07-01
Full Text Available In order to simulate the micro-evolutionary process of the microbial growth, [Methods] in this study, we adopt two-dimensional cellular automata as its growth space. Based on evolutionary mechanism of microbial and cell-cell interactions, we adopt Moore neighborhood and make the transition rules. Finally, we construct the microbial growth model. [Results] It can describe the relationships among the cell growth, division and death. And also can effectively reflect spatial inhibition effect and substrate limitation effect. [Conclusions] The simulation results show that CA model is not only consistent with the classic microbial kinetic model, but also be able to simulate the microbial growth and evolution.
Simulation of a mass-spring model for global deformation
Tong CUI; Aiguo SONG; Juan WU
2009-01-01
This article addresses a largely open problem in haptic simulation and rendering:contact force and deformation modeling for haptic simulation of a discrete globe mass-spring model,especially for global deforma-tion.The mass-spring system is composed of nodes connected with radially distributed springs.We tackle the problem using the theory of virtual work,and relations between the virtual force and nodal displacements are analyzed to obtain elastic deformations.The global deformation is controlled by the total nodal deformations based on a force equation at each node.The simulation results verify the efficiency of the contact force and deformation model with reasonable realism.
VEHICLE SIMULATION MODEL FOR DEVELOPING AN INTELLIGENT SLOPE SHIFT STRATEGY
Jin Hui; Ge Anlin
2004-01-01
With the rapid development of electronics and the growing demand for higher vehicle performance,intelligent shift technology is becoming increasingly important,and it promises to be a developing trend in vehicle automatic transmissions.A new simulation model is presented,which includes engine,powertrain,tire and vehicle dynamics models.Based on the model,simulation experiments are conducted to investigate the slope shift strategy.The data and conclusions obtained from the simulations are valuable contributions to the development of an intelligent slope shift strategy.
Adaptive deployment of model reductions for tau-leaping simulation
Wu, Sheng; Fu, Jin; Petzold, Linda R.
2015-05-01
Multiple time scales in cellular chemical reaction systems often render the tau-leaping algorithm inefficient. Various model reductions have been proposed to accelerate tau-leaping simulations. However, these are often identified and deployed manually, requiring expert knowledge. This is time-consuming and prone to error. In previous work, we proposed a methodology for automatic identification and validation of model reduction opportunities for tau-leaping simulation. Here, we show how the model reductions can be automatically and adaptively deployed during the time course of a simulation. For multiscale systems, this can result in substantial speedups.
LR-Spring Mass Model for Cardiac Surgical Simulation
Mosegaard, Jesper
2004-01-01
The purpose of the research conducted was to develop a real-time surgical simulator for preoperative planning of surgery in congenital heart disease. The main problem simulating procedures on cardiac morphology is the need for a large degree of detail and simulation speed. In combination...... with a demand for physically realistic real-time behaviour this gives us tradeoffs not easily balanced. The LR-Spring Mass model handles these constraints by the use of domain specific knowledge....
Games and simulations in distance learning: the AIDLET Model
Bidarra, José; Rothschild, Meagan; Squire, Kurt
2011-01-01
This chapter discusses the selection and potential use of electronic games and simulations in distance learning supported by an operational model called AIDLET. After analyzing the different approaches to the use of games and simulations in education, and discussing their benefits and shortcomings, a framework was developed to facilitate the selection, repurposing, design and implementation of games and simulations, with focus on the practical aspects of the processes used in Open and Distanc...
An Appraisal of Coupled Climate Model Simulations
Sperber, K; Gleckler, P; Covey, C; Taylor, K; Bader, D; Phillips, T; Fiorino, M; Achutarao, K
2004-02-24
In 2002, the Program for Climate Model Diagnosis and Intercomparison (PCMDI) proposed the concept for a state-of-the-science appraisal of climate models to be performed approximately every two years. Motivation for this idea arose from the perceived needs of the international modeling groups and the broader climate research community to document progress more frequently than provided by the Intergovernmental Panel on Climate Change (IPCC) Assessment Reports. A committee of external reviewers, which included senior researchers from four leading international modeling centers, supported the concept by stating in its review: ''The panel enthusiastically endorses the suggestion that PCMDI develop an independent appraisal of coupled model performance every 2-3 years. This would provide a useful 'mid-course' evaluation of modeling progress in the context of larger IPCC and national assessment activities, and should include both coupled and single-component model evaluations.''
Ainsworth, Nathan; Hariri, Ali; Prabakar, Kumaraguru; Pratt, Annabelle; Baggu, Murali
2016-11-21
Power hardware-in-the-loop (PHIL) simulation, where actual hardware under text is coupled with a real-time digital model in closed loop, is a powerful tool for analyzing new methods of control for emerging distributed power systems. However, without careful design and compensation of the interface between the simulated and actual systems, PHIL simulations may exhibit instability and modeling inaccuracies. This paper addresses issues that arise in the PHIL simulation of a hardware battery inverter interfaced with a simulated distribution feeder. Both the stability and accuracy issues are modeled and characterized, and a methodology for design of PHIL interface compensation to ensure stability and accuracy is presented. The stability and accuracy of the resulting compensated PHIL simulation is then shown by experiment.
Simulation modeling of outcomes and cost effectiveness.
Ramsey, S D; McIntosh, M; Etzioni, R; Urban, N
2000-08-01
Modeling will continue to be used to address important issues in clinical practice and health policy issues that have not been adequately studied with high-quality clinical trials. The apparent ad hoc nature of models belies the methodologic rigor that is applied to create the best models in cancer prevention and care. Models have progressed from simple decision trees to extremely complex microsimulation analyses, yet all are built using a logical process based on objective evaluation of the path between intervention and outcome. The best modelers take great care to justify both the structure and content of the model and then test their assumptions using a comprehensive process of sensitivity analysis and model validation. Like clinical trials, models sometimes produce results that are later found to be invalid as other data become available. When weighing the value of models in health care decision making, it is reasonable to consider the alternatives. In the absence of data, clinical policy decisions are often based on the recommendations of expert opinion panels or on poorly defined notions of the standard of care or medical necessity. Because such decision making rarely entails the rigorous process of data collection, synthesis, and testing that is the core of well-conducted modeling, it is usually not possible for external audiences to examine the assumptions and data that were used to derive the decisions. One of the modeler's most challenging tasks is to make the structure and content of the model transparent to the intended audience. The purpose of this article is to clarify the process of modeling, so that readers of models are more knowledgeable about their uses, strengths, and limitations.
National Aeronautics and Space Administration — There are significant logistical barriers to entry-level high performance computing (HPC) modeling and simulation (M&S) users. Performing large-scale, massively...
A flexible architecture for modeling and simulation of diffusional association
Haack, Fiete; Uhrmacher, Adelinde M; 10.4204/EPTCS.19.5
2010-01-01
Up to now, it is not possible to obtain analytical solutions for complex molecular association processes (e.g. Molecule recognition in Signaling or catalysis). Instead Brownian Dynamics (BD) simulations are commonly used to estimate the rate of diffusional association, e.g. to be later used in mesoscopic simulations. Meanwhile a portfolio of diffusional association (DA) methods have been developed that exploit BD. However, DA methods do not clearly distinguish between modeling, simulation, and experiment settings. This hampers to classify and compare the existing methods with respect to, for instance model assumptions, simulation approximations or specific optimization strategies for steering the computation of trajectories. To address this deficiency we propose FADA (Flexible Architecture for Diffusional Association) - an architecture that allows the flexible definition of the experiment comprising a formal description of the model in SpacePi, different simulators, as well as validation and analysis methods....
Modification of Core Model for KNTC 2 Simulator
Lee, Y.K.; Lee, J.G.; Park, J.E.; Bae, S.N.; Chin, H.C. [Korea Electric Power Research Institute, Taejeon (Korea, Republic of)
1997-12-31
KNTC 2 simulator was developed in 1986 referencing YGN 1. Since the YGN 1 has changed its fuel cycle to long term cycle(cycle 9), the data such as rod worth, boron worth, moderator temperature coefficient, and etc. of the simulator and those of the YGN 1 became different. To incorporate these changes into the simulator and make the simulator more close to the reference plant, core model upgrade became a necessity. During this research, core data for the simulator was newly generated using APA of the WH. And to make it easy tuning and verification of the key characteristics of the reactor model, PC-Based tool was also developed. And to facilitate later core model upgrade, two procedures-`the Procedures for core characteristic generation` and `the Procedures for core characteristic modification`-were also developed. (author). 16 refs., 22 figs., 1 tab.
Modeling and simulation of Si crystal growth from melt
Liu, Lijun; Liu, Xin; Li, Zaoyang [National Engineering Research Center for Fluid Machinery and Compressors, School of Energy and Power Engineering, Xi' an Jiaotong University, Xi' an, Shaanxi 710049 (China); Miyazawa, Hiroaki; Nakano, Satoshi; Kakimoto, Koichi [Research Institute for Applied Mechanics, Kyushu University, Kasuga 816-8580 (Japan)
2009-07-01
A numerical simulator was developed with a global model of heat transfer for any crystal growth taking place at high temperature. Convective, conductive and radiative heat transfers in the furnace are solved together in a conjugated way by a finite volume method. A three-dimensional (3D) global model was especially developed for simulation of heat transfer in any crystal growth with 3D features. The model enables 3D global simulation be conducted with moderate requirement of computer resources. The application of this numerical simulator to a CZ growth and a directional solidification process for Si crystals, the two major production methods for crystalline Si for solar cells, was introduced. Some typical results were presented, showing the importance and effectiveness of numerical simulation in analyzing and improving these kinds of Si crystal growth processes from melt. (copyright 2009 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)
COMPARISON OF RF CAVITY TRANSPORT MODELS FOR BBU SIMULATIONS
Ilkyoung Shin,Byung Yunn,Todd Satogata,Shahid Ahmed
2011-03-01
The transverse focusing effect in RF cavities plays a considerable role in beam dynamics for low-energy beamline sections and can contribute to beam breakup (BBU) instability. The purpose of this analysis is to examine RF cavity models in simulation codes which will be used for BBU experiments at Jefferson Lab and improve BBU simulation results. We review two RF cavity models in the simulation codes elegant and TDBBU (a BBU simulation code developed at Jefferson Lab). elegant can include the Rosenzweig-Serafini (R-S) model for the RF focusing effect. Whereas TDBBU uses a model from the code TRANSPORT which considers the adiabatic damping effect, but not the RF focusing effect. Quantitative comparisons are discussed for the CEBAF beamline. We also compare the R-S model with the results from numerical simulations for a CEBAF-type 5-cell superconducting cavity to validate the use of the R-S model as an improved low-energy RF cavity transport model in TDBBU. We have implemented the R-S model in TDBBU. It will improve BBU simulation results to be more matched with analytic calculations and experimental results.
Silvis, Maurits H
2015-01-01
Assuming a general constitutive relation for the turbulent stresses in terms of the local large-scale velocity gradient, we constructed a class of subgrid-scale models for large-eddy simulation that are consistent with important physical and mathematical properties. In particular, they preserve symmetries of the Navier-Stokes equations and exhibit the proper near-wall scaling. They furthermore show desirable dissipation behavior and are capable of describing nondissipative effects. We provided examples of such physically-consistent models and showed that existing subgrid-scale models do not all satisfy the desired properties.
Ground Contact Model for Mars Science Laboratory Mission Simulations
Raiszadeh, Behzad; Way, David
2012-01-01
The Program to Optimize Simulated Trajectories II (POST 2) has been successful in simulating the flight of launch vehicles and entry bodies on earth and other planets. POST 2 has been the primary simulation tool for the Entry Descent, and Landing (EDL) phase of numerous Mars lander missions such as Mars Pathfinder in 1997, the twin Mars Exploration Rovers (MER-A and MER-B) in 2004, Mars Phoenix lander in 2007, and it is now the main trajectory simulation tool for Mars Science Laboratory (MSL) in 2012. In all previous missions, the POST 2 simulation ended before ground impact, and a tool other than POST 2 simulated landing dynamics. It would be ideal for one tool to simulate the entire EDL sequence, thus avoiding errors that could be introduced by handing off position, velocity, or other fight parameters from one simulation to the other. The desire to have one continuous end-to-end simulation was the motivation for developing the ground interaction model in POST 2. Rover landing, including the detection of the postlanding state, is a very critical part of the MSL mission, as the EDL landing sequence continues for a few seconds after landing. The method explained in this paper illustrates how a simple ground force interaction model has been added to POST 2, which allows simulation of the entire EDL from atmospheric entry through touchdown.
A Novel Software Simulator Model Based on Active Hybrid Architecture
Amr AbdElHamid
2015-01-01
Full Text Available The simulated training is an important issue for any type of missions such as aerial, ground, sea, or even space missions. In this paper, a new flexible aerial simulator based on active hybrid architecture is introduced. The simulator infrastructure is applicable to any type of training missions and research activities. This software-based simulator is tested on aerial missions to prove its applicability within time critical systems. The proposed active hybrid architecture is introduced via using the VB.NET and MATLAB in the same simulation loop. It exploits the remarkable computational power of MATLAB as a backbone aircraft model, and such mathematical model provides realistic dynamics to the trainee. Meanwhile, the Human-Machine Interface (HMI, the mission planning, the hardware interfacing, data logging, and MATLAB interfacing are developed using VB.NET. The proposed simulator is flexible enough to perform navigation and obstacle avoidance training missions. The active hybrid architecture is used during the simulated training, and also through postmission activities (like the generation of signals playback reports for evaluation purposes. The results show the ability of the proposed architecture to fulfill the aerial simulator demands and to provide a flexible infrastructure for different simulated mission requirements. Finally, a comparison with some existing simulators is introduced.
A perspective on modeling and simulation of complex dynamical systems
Åström, K. J.
2011-09-01
There has been an amazing development of modeling and simulation from its beginning in the 1920s, when the technology was available only at a handful of University groups who had access to a mechanical differential analyzer. Today, tools for modeling and simulation are available for every student and engineer. This paper gives a perspective on the development with particular emphasis on technology and paradigm shifts. Modeling is increasingly important for design and operation of complex natural and man-made systems. Because of the increased use of model based control such as Kalman filters and model predictive control, models are also appearing as components of feedback systems. Modeling and simulation are multidisciplinary, it is used in a wide variety of fields and their development have been strongly influenced by mathematics, numerics, computer science and computer technology.
A Study of the Simulation Model in WCDMA Systems
无
2002-01-01
@@ In this dissertation, we establish an end-to-end simulation model for the performance evaluation of WCDMA/ATM-based third-generation cellular systems where we take into account the quality of services in the integrated voice-data environment. This dissertation aims to provide a framework for performance analysis and evaluation of algorithms in mobile networks. In order to model such a complicated system, three challenges face us: modeling the wireless channel, modeling the traffic sources and modeling the broadband access network. In Chapter 1, the architecture of this system simulation model is concisely described. The author's contribution is to propose an abstract model of the air interface that has the same abstraction level as the broadband access network, which makes the integration of radio links and transport infrastructure feasible. The most important parts of this dissertation are in-depth researches on the three critical problems we mentioned above. Foreach topic, we derive an analytical model and implement it using Block Oriented Network Simulator (BONeS) of Cadence Corporation, USA.In Chapter 2, a digital channel model is established based on the simulation testbed which has developed successfully in the wireless communication laboratory in BUPT. This channel model is a key block in the abstract air-interface simulation module. The author's contributions are:
Tidal simulation using regional ocean modeling systems (ROMS)
Wang, Xiaochun; Chao, Yi; Li, Zhijin; Dong, Changming; Farrara, John; McWilliams, James C.; Shum, C. K.; Wang, Yu; Matsumoto, Koji; Rosenfeld, Leslie K.; Paduan, Jeffrey D.
2006-01-01
The purpose of our research is to test the capability of ROMS in simulating tides. The research also serves as a necessary exercise to implement tides in an operational ocean forecasting system. In this paper, we emphasize the validation of the model tide simulation. The characteristics and energetics of tides of the region will be reported in separate publications.