WorldWideScience

Sample records for minimum detection limits

  1. Minimum detection limit and spatial resolution of thin-sample field-emission electron probe microanalysis

    International Nuclear Information System (INIS)

    Kubo, Yugo; Hamada, Kotaro; Urano, Akira

    2013-01-01

    The minimum detection limit and spatial resolution for a thinned semiconductor sample were determined by electron probe microanalysis (EPMA) using a Schottky field emission (FE) electron gun and wavelength dispersive X-ray spectrometry. Comparison of the FE-EPMA results with those obtained using energy dispersive X-ray spectrometry in conjunction with scanning transmission electron microscopy, confirmed that FE-EPMA is largely superior in terms of detection sensitivity. Thin-sample FE-EPMA is demonstrated as a very effective method for high resolution, high sensitivity analysis in a laboratory environment because a high probe current and high signal-to-noise ratio can be achieved. - Highlights: • Minimum detection limit and spatial resolution determined for FE-EPMA. • Detection sensitivity of FE-EPMA greatly superior to that of STEM-EDX. • Minimum detection limit and spatial resolution controllable by probe current

  2. 22 CFR 151.4 - Minimum limits for motor vehicle insurance.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Minimum limits for motor vehicle insurance. 151.4 Section 151.4 Foreign Relations DEPARTMENT OF STATE DIPLOMATIC PRIVILEGES AND IMMUNITIES COMPULSORY LIABILITY INSURANCE FOR DIPLOMATIC MISSIONS AND PERSONNEL § 151.4 Minimum limits for motor vehicle...

  3. Detection of minimum-ionizing particles in hydrogenated amorphous silicon

    International Nuclear Information System (INIS)

    Kaplan, S.N.; Fujieda, I.; Perez-Mendez, V.; Qureshi, S.; Ward, W.; Street, R.A.

    1987-09-01

    Based on previously-reported results of the successful detection of alpha particles and 1- and 2-MeV protons with hydrogenated amorphous silicon (a-Si : H) diodes, detection of a single minimum-ionizing particle will require a total sensitive thickness of approximately 100 to 150 μm, either in the form of a single thick diode, or as a stack of several thinner diodes. Signal saturation at high dE/dx makes it necessary to simulate minimum ionization in order to evaluate present detectors. Two techniques, using pulsed infrared light, and pulsed x-rays, give single-pulse signals large enough for direct measurements. A third, using beta rays, requires multiple-transit signal averaging to produce signals measurable above noise. Signal amplitudes from the a-Si : H limit at 60% of the signal size from Si crystals extrapolated to the same thickness. This is consistent with an a-Si : H radiation ionization energy, W = 6 eV/electron-hole pair. Beta-ray signals are observed at the expected amplitude

  4. Minimum detectable gas concentration performance evaluation method for gas leak infrared imaging detection systems.

    Science.gov (United States)

    Zhang, Xu; Jin, Weiqi; Li, Jiakun; Wang, Xia; Li, Shuo

    2017-04-01

    Thermal imaging technology is an effective means of detecting hazardous gas leaks. Much attention has been paid to evaluation of the performance of gas leak infrared imaging detection systems due to several potential applications. The minimum resolvable temperature difference (MRTD) and the minimum detectable temperature difference (MDTD) are commonly used as the main indicators of thermal imaging system performance. This paper establishes a minimum detectable gas concentration (MDGC) performance evaluation model based on the definition and derivation of MDTD. We proposed the direct calculation and equivalent calculation method of MDGC based on the MDTD measurement system. We build an experimental MDGC measurement system, which indicates the MDGC model can describe the detection performance of a thermal imaging system to typical gases. The direct calculation, equivalent calculation, and direct measurement results are consistent. The MDGC and the minimum resolvable gas concentration (MRGC) model can effectively describe the performance of "detection" and "spatial detail resolution" of thermal imaging systems to gas leak, respectively, and constitute the main performance indicators of gas leak detection systems.

  5. Minimum Delay Moving Object Detection

    KAUST Repository

    Lao, Dong

    2017-11-09

    We present a general framework and method for detection of an object in a video based on apparent motion. The object moves relative to background motion at some unknown time in the video, and the goal is to detect and segment the object as soon it moves in an online manner. Due to unreliability of motion between frames, more than two frames are needed to reliably detect the object. Our method is designed to detect the object(s) with minimum delay, i.e., frames after the object moves, constraining the false alarms. Experiments on a new extensive dataset for moving object detection show that our method achieves less delay for all false alarm constraints than existing state-of-the-art.

  6. Minimum Delay Moving Object Detection

    KAUST Repository

    Lao, Dong

    2017-01-08

    We present a general framework and method for detection of an object in a video based on apparent motion. The object moves relative to background motion at some unknown time in the video, and the goal is to detect and segment the object as soon it moves in an online manner. Due to unreliability of motion between frames, more than two frames are needed to reliably detect the object. Our method is designed to detect the object(s) with minimum delay, i.e., frames after the object moves, constraining the false alarms. Experiments on a new extensive dataset for moving object detection show that our method achieves less delay for all false alarm constraints than existing state-of-the-art.

  7. Minimum Delay Moving Object Detection

    KAUST Repository

    Lao, Dong; Sundaramoorthi, Ganesh

    2017-01-01

    We present a general framework and method for detection of an object in a video based on apparent motion. The object moves relative to background motion at some unknown time in the video, and the goal is to detect and segment the object as soon it moves in an online manner. Due to unreliability of motion between frames, more than two frames are needed to reliably detect the object. Our method is designed to detect the object(s) with minimum delay, i.e., frames after the object moves, constraining the false alarms. Experiments on a new extensive dataset for moving object detection show that our method achieves less delay for all false alarm constraints than existing state-of-the-art.

  8. Minimum Delay Moving Object Detection

    KAUST Repository

    Lao, Dong

    2017-05-14

    This thesis presents a general framework and method for detection of an object in a video based on apparent motion. The object moves, at some unknown time, differently than the “background” motion, which can be induced from camera motion. The goal of proposed method is to detect and segment the object as soon it moves in an online manner. Since motion estimation can be unreliable between frames, more than two frames are needed to reliably detect the object. Observing more frames before declaring a detection may lead to a more accurate detection and segmentation, since more motion may be observed leading to a stronger motion cue. However, this leads to greater delay. The proposed method is designed to detect the object(s) with minimum delay, i.e., frames after the object moves, constraining the false alarms, defined as declarations of detection before the object moves or incorrect or inaccurate segmentation at the detection time. Experiments on a new extensive dataset for moving object detection show that our method achieves less delay for all false alarm constraints than existing state-of-the-art.

  9. Correction to the count-rate detection limit and sample/blank time-allocation methods

    International Nuclear Information System (INIS)

    Alvarez, Joseph L.

    2013-01-01

    A common form of count-rate detection limits contains a propagation of uncertainty error. This error originated in methods to minimize uncertainty in the subtraction of the blank counts from the gross sample counts by allocation of blank and sample counting times. Correct uncertainty propagation showed that the time allocation equations have no solution. This publication presents the correct form of count-rate detection limits. -- Highlights: •The paper demonstrated a proper method of propagating uncertainty of count rate differences. •The standard count-rate detection limits were in error. •Count-time allocation methods for minimum uncertainty were in error. •The paper presented the correct form of the count-rate detection limit. •The paper discussed the confusion between count-rate uncertainty and count uncertainty

  10. Verification of Minimum Detectable Activity for Radiological Threat Source Search

    Science.gov (United States)

    Gardiner, Hannah; Myjak, Mitchell; Baciak, James; Detwiler, Rebecca; Seifert, Carolyn

    2015-10-01

    The Department of Homeland Security's Domestic Nuclear Detection Office is working to develop advanced technologies that will improve the ability to detect, localize, and identify radiological and nuclear sources from airborne platforms. The Airborne Radiological Enhanced-sensor System (ARES) program is developing advanced data fusion algorithms for analyzing data from a helicopter-mounted radiation detector. This detector platform provides a rapid, wide-area assessment of radiological conditions at ground level. The NSCRAD (Nuisance-rejection Spectral Comparison Ratios for Anomaly Detection) algorithm was developed to distinguish low-count sources of interest from benign naturally occurring radiation and irrelevant nuisance sources. It uses a number of broad, overlapping regions of interest to statistically compare each newly measured spectrum with the current estimate for the background to identify anomalies. We recently developed a method to estimate the minimum detectable activity (MDA) of NSCRAD in real time. We present this method here and report on the MDA verification using both laboratory measurements and simulated injects on measured backgrounds at or near the detection limits. This work is supported by the US Department of Homeland Security, Domestic Nuclear Detection Office, under competitively awarded contract/IAA HSHQDC-12-X-00376. This support does not constitute an express or implied endorsement on the part of the Gov't.

  11. Discuss the technology for decrease the detection limit of NaI(Tl) gamma spectrometer

    International Nuclear Information System (INIS)

    Guo Xiaobin; Qu Guopu; Liu Zhiying; Wang Hongyan; Wang Lieming

    2011-01-01

    The radioelement species is complex and quantity is few after nuclear explosion, thus it is hard to tell the difference when using the Nal (TI) Gamma spectrometer detection due to several kinds of the peak of nuclide overlapped in the scattering region. So there is a high demand for spectrometer stability, energy resolution, solution spectrum and minimum detective activity. The paper analysed the influenced factors to Nal (TI) Gamma spectrometer and the measures of detection limit decrease by experiments and MCNP simulation, which proposed the methods to reduce background through shielding in order to improve minimum detective activity. The experiment shows that choosing reasonable shielding can reduce the background effectively and improve the spectrometer low level radioactive detect ability. (authors)

  12. Minimum Detectable Activity for Tomographic Gamma Scanning System

    Energy Technology Data Exchange (ETDEWEB)

    Venkataraman, Ram [Canberra Industries (AREVA BDNM), Meriden, CT (United States); Smith, Susan [Canberra Industries (AREVA BDNM), Meriden, CT (United States); Kirkpatrick, J. M. [Canberra Industries (AREVA BDNM), Meriden, CT (United States); Croft, Stephen [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-01-01

    For any radiation measurement system, it is useful to explore and establish the detection limits and a minimum detectable activity (MDA) for the radionuclides of interest, even if the system is to be used at far higher values. The MDA serves as an important figure of merit, and often a system is optimized and configured so that it can meet the MDA requirements of a measurement campaign. The non-destructive assay (NDA) systems based on gamma ray analysis are no exception and well established conventions, such the Currie method, exist for estimating the detection limits and the MDA. However, the Tomographic Gamma Scanning (TGS) technique poses some challenges for the estimation of detection limits and MDAs. The TGS combines high resolution gamma ray spectrometry (HRGS) with low spatial resolution image reconstruction techniques. In non-imaging gamma ray based NDA techniques measured counts in a full energy peak can be used to estimate the activity of a radionuclide, independently of other counting trials. However, in the case of the TGS each “view” is a full spectral grab (each a counting trial), and each scan consists of 150 spectral grabs in the transmission and emission scans per vertical layer of the item. The set of views in a complete scan are then used to solve for the radionuclide activities on a voxel by voxel basis, over 16 layers of a 10x10 voxel grid. Thus, the raw count data are not independent trials any more, but rather constitute input to a matrix solution for the emission image values at the various locations inside the item volume used in the reconstruction. So, the validity of the methods used to estimate MDA for an imaging technique such as TGS warrant a close scrutiny, because the pair-counting concept of Currie is not directly applicable. One can also raise questions as to whether the TGS, along with other image reconstruction techniques which heavily intertwine data, is a suitable method if one expects to measure samples whose activities

  13. Signal detection without finite-energy limits to quantum resolution

    OpenAIRE

    Luis Aina, Alfredo

    2013-01-01

    We show that there are extremely simple signal detection schemes where the finiteness of energy resources places no limit on the resolution. On the contrary, larger resolution can be obtained with lower energy. To this end the generator of the signal-dependent transformation encoding the signal information on the probe state must be different from the energy. We show that the larger the deviation of the probe state from being the minimum-uncertainty state, the better the resolution.

  14. A Computable Plug-In Estimator of Minimum Volume Sets for Novelty Detection

    KAUST Repository

    Park, Chiwoo; Huang, Jianhua Z.; Ding, Yu

    2010-01-01

    A minimum volume set of a probability density is a region of minimum size among the regions covering a given probability mass of the density. Effective methods for finding the minimum volume sets are very useful for detecting failures or anomalies in commercial and security applications-a problem known as novelty detection. One theoretical approach of estimating the minimum volume set is to use a density level set where a kernel density estimator is plugged into the optimization problem that yields the appropriate level. Such a plug-in estimator is not of practical use because solving the corresponding minimization problem is usually intractable. A modified plug-in estimator was proposed by Hyndman in 1996 to overcome the computation difficulty of the theoretical approach but is not well studied in the literature. In this paper, we provide theoretical support to this estimator by showing its asymptotic consistency. We also show that this estimator is very competitive to other existing novelty detection methods through an extensive empirical study. ©2010 INFORMS.

  15. A Computable Plug-In Estimator of Minimum Volume Sets for Novelty Detection

    KAUST Repository

    Park, Chiwoo

    2010-10-01

    A minimum volume set of a probability density is a region of minimum size among the regions covering a given probability mass of the density. Effective methods for finding the minimum volume sets are very useful for detecting failures or anomalies in commercial and security applications-a problem known as novelty detection. One theoretical approach of estimating the minimum volume set is to use a density level set where a kernel density estimator is plugged into the optimization problem that yields the appropriate level. Such a plug-in estimator is not of practical use because solving the corresponding minimization problem is usually intractable. A modified plug-in estimator was proposed by Hyndman in 1996 to overcome the computation difficulty of the theoretical approach but is not well studied in the literature. In this paper, we provide theoretical support to this estimator by showing its asymptotic consistency. We also show that this estimator is very competitive to other existing novelty detection methods through an extensive empirical study. ©2010 INFORMS.

  16. Calculation of the detection limit in radiation measurements with systematic uncertainties

    International Nuclear Information System (INIS)

    Kirkpatrick, J.M.; Russ, W.; Venkataraman, R.; Young, B.M.

    2015-01-01

    The detection limit (L D ) or Minimum Detectable Activity (MDA) is an a priori evaluation of assay sensitivity intended to quantify the suitability of an instrument or measurement arrangement for the needs of a given application. Traditional approaches as pioneered by Currie rely on Gaussian approximations to yield simple, closed-form solutions, and neglect the effects of systematic uncertainties in the instrument calibration. These approximations are applicable over a wide range of applications, but are of limited use in low-count applications, when high confidence values are required, or when systematic uncertainties are significant. One proposed modification to the Currie formulation attempts account for systematic uncertainties within a Gaussian framework. We have previously shown that this approach results in an approximation formula that works best only for small values of the relative systematic uncertainty, for which the modification of Currie's method is the least necessary, and that it significantly overestimates the detection limit or gives infinite or otherwise non-physical results for larger systematic uncertainties where such a correction would be the most useful. We have developed an alternative approach for calculating detection limits based on realistic statistical modeling of the counting distributions which accurately represents statistical and systematic uncertainties. Instead of a closed form solution, numerical and iterative methods are used to evaluate the result. Accurate detection limits can be obtained by this method for the general case

  17. Material limitations on the detection limit in refractometry.

    Science.gov (United States)

    Skafte-Pedersen, Peder; Nunes, Pedro S; Xiao, Sanshui; Mortensen, Niels Asger

    2009-01-01

    We discuss the detection limit for refractometric sensors relying on high-Q optical cavities and show that the ultimate classical detection limit is given by min {Δn} ≳ η, with n + iη being the complex refractive index of the material under refractometric investigation. Taking finite Q factors and filling fractions into account, the detection limit declines. As an example we discuss the fundamental limits of silicon-based high-Q resonators, such as photonic crystal resonators, for sensing in a bio-liquid environment, such as a water buffer. In the transparency window (λ ≳ 1100 nm) of silicon the detection limit becomes almost independent on the filling fraction, while in the visible, the detection limit depends strongly on the filling fraction because the silicon absorbs strongly.

  18. Material Limitations on the Detection Limit in Refractometry

    Directory of Open Access Journals (Sweden)

    Niels Asger Mortensen

    2009-10-01

    Full Text Available We discuss the detection limit for refractometric sensors relying on high-Q optical cavities and show that the ultimate classical detection limit is given by min {Δn} ≳ η with n + iη being the complex refractive index of the material under refractometric investigation. Taking finite Q factors and filling fractions into account, the detection limit declines. As an example we discuss the fundamental limits of silicon-based high-Q resonators, such as photonic crystal resonators, for sensing in a bio-liquid environment, such as a water buffer. In the transparency window (λ ≳ 1100 nm of silicon the detection limit becomes almost independent on the filling fraction, while in the visible, the detection limit depends strongly on the filling fraction because the silicon absorbs strongly.

  19. Reliability and Minimum Detectable Change of Temporal-Spatial, Kinematic, and Dynamic Stability Measures during Perturbed Gait.

    Directory of Open Access Journals (Sweden)

    Christopher A Rábago

    Full Text Available Temporal-spatial, kinematic variability, and dynamic stability measures collected during perturbation-based assessment paradigms are often used to identify dysfunction associated with gait instability. However, it remains unclear which measures are most reliable for detecting and tracking responses to perturbations. This study systematically determined the between-session reliability and minimum detectable change values of temporal-spatial, kinematic variability, and dynamic stability measures during three types of perturbed gait. Twenty young healthy adults completed two identical testing sessions two weeks apart, comprised of an unperturbed and three perturbed (cognitive, physical, and visual walking conditions in a virtual reality environment. Within each session, perturbation responses were compared to unperturbed walking using paired t-tests. Between-session reliability and minimum detectable change values were also calculated for each measure and condition. All temporal-spatial, kinematic variability and dynamic stability measures demonstrated fair to excellent between-session reliability. Minimal detectable change values, normalized to mean values ranged from 1-50%. Step width mean and variability measures demonstrated the greatest response to perturbations with excellent between-session reliability and low minimum detectable change values. Orbital stability measures demonstrated specificity to perturbation direction and sensitivity with excellent between-session reliability and low minimum detectable change values. We observed substantially greater between-session reliability and lower minimum detectable change values for local stability measures than previously described which may be the result of averaging across trials within a session and using velocity versus acceleration data for reconstruction of state spaces. Across all perturbation types, temporal-spatial, orbital and local measures were the most reliable measures with the

  20. Material Limitations on the Detection Limit in Refractometry

    OpenAIRE

    Skafte-Pedersen, Peder; Nunes, Pedro S.; Xiao, Sanshui; Mortensen, Niels Asger

    2009-01-01

    We discuss the detection limit for refractometric sensors relying on high-Q optical cavities and show that the ultimate classical detection limit is given by min {Δn} ≳ η with n + iη being the complex refractive index of the material under refractometric investigation. Taking finite Q factors and filling fractions into account, the detection limit declines. As an example we discuss the fundamental limits of silicon-based high-Q resonators, such as photonic crystal resonators, for sensing in a...

  1. Minimum ionizing particle detection using amorphous silicon diodes

    Energy Technology Data Exchange (ETDEWEB)

    Xi, J.; Hollingsworth, R.E.; Buitrago, R.H. (Glasstech Solar, Inc., Wheat Ridge, CO (USA)); Oakley, D.; Cumalat, J.P.; Nauenberg, U. (Colorado Univ., Boulder (USA). Dept. of Physics); McNeil, J.A. (Colorado School of Mines, Golden (USA). Dept. of Physics); Anderson, D.F. (Fermi National Accelerator Lab., Batavia, IL (USA)); Perez-Mendez, V. (Lawrence Berkeley Lab., CA (USA))

    1991-03-01

    Hydrogenated amorphous silicon pin diodes have been used to detect minimum ionizing electrons with a pulse height signal-to-noise ratio exceeding 3. A distinct signal was seen for shaping times from 100 to 3000 ns. The devices used had a 54 {mu}m thick intrinsic layer and an active area of 0.1 cm{sup 2}. The maximum signal was 3200 electrons with a noise width of 950 electrons for a shaping time of 250 ns. (orig.).

  2. Energy-minimum sub-threshold self-timed circuits using current-sensing completion detection

    DEFF Research Database (Denmark)

    Akgun, O. C.; Rodrigues, J. N.; Sparsø, Jens

    2011-01-01

    This study addresses the design of self-timed energy-minimum circuits, operating in the sub-VT domain and a generic implementation template using bundled-data circuitry and current sensing completion detection (CSCD). Furthermore, a fully decoupled latch controller was developed, which integrates......V. Spice simulations indicate a gain of 52.58% in throughput because of asynchronous operation. By trading the throughput improvement, energy dissipation is reduced by 16.8% at the energy-minimum supply voltage....

  3. Material limitations on the detection limit in refractometry

    DEFF Research Database (Denmark)

    Skafte-Pedersen, Peder; Nunes, Pedro; Xiao, Sanshui

    2009-01-01

    We discuss the detection limit for refractometric sensors relying on high-Q optical cavities and show that the ultimate classical detection limit is given by min {Δn} ≳ η with n + iη being the complex refractive index of the material under refractometric investigation. Taking finite Q factors and...

  4. Estimation of minimum detectable concentration of chlorine in the blast furnace slag cement concrete

    Energy Technology Data Exchange (ETDEWEB)

    Naqvi, A.A., E-mail: aanaqvi@kfupm.edu.s [Department of Physics, King Fahd University of Petroleum and Minerals, Dhahran 31261 (Saudi Arabia); Maslehuddin, M. [Center for Engineering Research, King Fahd University of Petroleum and Minerals, Dhahran 31261 (Saudi Arabia); Garwan, M.A.; Nagadi, M.M. [Department of Physics, King Fahd University of Petroleum and Minerals, Dhahran 31261 (Saudi Arabia); Al-Amoudi, O.S.B. [Department of Civil Engineering, King Fahd University of Petroleum and Minerals, Dhahran 31261 (Saudi Arabia); Khateeb-ur-Rehman,; Raashid, M. [Department of Physics, King Fahd University of Petroleum and Minerals, Dhahran 31261 (Saudi Arabia)

    2011-01-01

    The Prompt Gamma Neutron Activation Analysis technique was used to measure the concentration of chloride in the blast furnace slag (BFS) cement concrete to assess the possibility of reinforcement corrosion. The experimental setup was optimized using Monte Carlo calculations. The BFS concrete specimens containing 0.8-3.5 wt.% chloride were prepared and the concentration of chlorine was evaluated by determining the yield of 6.11, 6.62, 7.41, 7.79 and 8.58 MeV gamma-rays. The Minimum Detectable Concentration (MDC) of chlorine in the BFS cement concrete was estimated. The best value of MDC limit of chlorine in the BFS cement concrete was found to be 0.034 {+-} 0.011 and 0.038 {+-} 0.012 wt.% for 6.11 and 6.62 MeV prompt gamma-rays. Within the statistical uncertainty the lower bound of the measured MDC of chlorine in the BFS cement concrete meets the maximum permissible limit of 0.03 wt.% of chloride set by the American Concrete Institute.

  5. Minimum Symbol Error Rate Detection in Single-Input Multiple-Output Channels with Markov Noise

    DEFF Research Database (Denmark)

    Christensen, Lars P.B.

    2005-01-01

    Minimum symbol error rate detection in Single-Input Multiple- Output(SIMO) channels with Markov noise is presented. The special case of zero-mean Gauss-Markov noise is examined closer as it only requires knowledge of the second-order moments. In this special case, it is shown that optimal detection...

  6. Aerosol quantification with the Aerodyne Aerosol Mass Spectrometer: detection limits and ionizer background effects

    Directory of Open Access Journals (Sweden)

    S. Borrmann

    2009-02-01

    Full Text Available Systematic laboratory experiments were performed to investigate quantification of various species with two versions of the Aerodyne Aerosol Mass Spectrometer, a Quadrupole Aerosol Mass Spectrometer (Q-AMS and a compact Time-of-Flight Aerosol Mass Spectrometer (c-ToF-AMS. Here we present a new method to continuously determine the detection limits of the AMS analyzers during regular measurements, yielding detection limit (DL information under various measurement conditions. Minimum detection limits range from 0.03 μg m−3 (nitrate, sulfate, and chloride up to 0.5 μg m−3 (organics for the Q-AMS. Those of the c-ToF-AMS are found between 0.003 μg m−3 (nitrate, sulfate and 0.03 μg m−3 (ammonium, organics. The DL values found for the c-ToF-AMS were ~10 times lower than those of the Q-AMS, mainly due to differences in ion duty cycle. Effects causing an increase of the detection limits include long-term instrument contamination, measurement of high aerosol mass concentrations and short-term instrument history. The self-cleaning processes which reduce the instrument background after measurement of large aerosol concentrations as well as the influences of increased instrument background on mass concentration measurements are discussed. Finally, improvement of detection limits by extension of averaging time intervals, selected or reduced ion monitoring, and variation of particle-to-background measurement ratio are investigated.

  7. Preliminary minimum detectable limit measurements in 208-L drums for selected actinide isotopes in mock-waste matrices

    International Nuclear Information System (INIS)

    Camp, D.C.; Wang, Tzu-Fang; Martz, H.E.

    1992-01-01

    Preliminary minimum detectable levels (MDLS) of selected actinide isotopes have been determined in full-scale, 55-gallon drums filled with a range of mock-waste materials from combustibles (0.14 g/CM 3 ) to sand (1.7 g/CM 3 ). Measurements were recorded from 100 to 10,000 seconds with selected actinide sources located in these drums at an edge position, on the center axis of a drum and midway between these two positions. Measurements were also made with a 166 Ho source to evaluate the attenuation of these mock-matrix materials as a function of energy. By knowing where the source activity is located within a drum, our preliminary results show that a simply collimated 90% HPGE detector can differentiate between TRU (>100 nCi/g) and LLW amounts of 239 Pu in only 100s of measurement time and with sufficient accuracy in both low and medium density, low Z materials. Other actinides measured so far include 235 U, 241 Am, and 244 Cm. These measurements begin to establish the probable MDLs achievable in the nondestructive assays of real waste drums when using active and passive CT. How future measurements may differ from these preliminary measurements is also discussed

  8. Improvement in minimum detectable activity for low energy gamma by optimization in counting geometry

    Directory of Open Access Journals (Sweden)

    Anil Gupta

    2017-01-01

    Full Text Available Gamma spectrometry for environmental samples of low specific activities demands low minimum detection levels of measurement. An attempt has been made to lower the gamma detection level of measurement by optimizing the sample geometry, without compromising on the sample size. Gamma energy of 50–200 keV range was chosen for the study, since low energy gamma photons suffer the most self-attenuation within matrix. The simulation study was carried out using MCNP based software “EffCalcMC” for silica matrix and cylindrical geometries. A volume of 250 ml sample geometry of 9 cm diameter is optimized as the best suitable geometry for use, against the in-practice 7 cm diameter geometry of same volume. An increase in efficiency of 10%–23% was observed for the 50–200 keV gamma energy range and a corresponding lower minimum detectable activity of 9%–20% could be achieved for the same.

  9. Minimum detection efficiency for the loophole-free confirmation of quantum contextuality

    International Nuclear Information System (INIS)

    Xiang Yang; Hong Fang-Yu

    2013-01-01

    Klyachko—Can—Binicioğlu—Shumovsky (KCBS) inequality is a Bell-like inequality, the violation of which can be used to confirm the existence of quantum contextuality. However, the imperfection of detection efficiency may cause the so-called loophole in actual KCBS's experiments. We derive an alternative KCBS inequality to deal with the loophole in actual KCBS's experiments. We prove that if the experimental data violate this KCBS inequality, the loophole-free violation of the original KCBS inequality will occur. We show that the minimum detection efficiency needed for a loophole-free violation of the KCBS inequality is about 0.9738

  10. Minimum size limits for yellow perch (Perca flavescens) in western Lake Erie

    Science.gov (United States)

    Hartman, Wilbur L.; Nepszy, Stephen J.; Scholl, Russell L.

    1980-01-01

    During the 1960's yellow perch (Perca flavescens) of Lake Erie supported a commercial fishery that produced an average annual catch of 23 million pounds, as well as a modest sport fishery. Since 1969, the resource has seriously deteriorated. Commercial landings amounted to only 6 million pounds in 1976, and included proportionally more immature perch than in the 1960's. Moreover, no strong year classes were produced between 1965 and 1975. An interagency technical committee was appointed in 1975 by the Lake Erie Committee of the Great Lakes Fishery Commission to develop an interim management strategy that would provide for greater protection of perch in western Lake Erie, where declines have been the most severe. The committee first determined the age structure, growth and mortality rates, maturation schedule, and length-fecundity relationship for the population, and then applied Ricker-type equilibrium yield models to determine the effects of various minimum length limits on yield, production, average stock weight, potential egg deposition, and the Abrosov spawning frequency indicator (average number of spawning opportunities per female). The committee recommended increasing the minimum length limit of 5.0 inches to at least 8.5 inches. Theoretically, this change would increase the average stock weight by 36% and potential egg deposition by 44%, without significantly decreasing yield. Abrosov's spawning frequency indicator would rise from the existing 0.6 to about 1.2.

  11. Limits of detection and decision. Part 4

    International Nuclear Information System (INIS)

    Voigtman, E.

    2008-01-01

    Probability density functions (PDFs) have been derived for a number of commonly used limit of detection definitions, including several variants of the Relative Standard Deviation of the Background-Background Equivalent Concentration (RSDB-BEC) method, for a simple linear chemical measurement system (CMS) having homoscedastic, Gaussian measurement noise and using ordinary least squares (OLS) processing. All of these detection limit definitions serve as both decision and detection limits, thereby implicitly resulting in 50% rates of Type 2 errors. It has been demonstrated that these are closely related to Currie decision limits, if the coverage factor, k, is properly defined, and that all of the PDFs are scaled reciprocals of noncentral t variates. All of the detection limits have well-defined upper and lower limits, thereby resulting in finite moments and confidence limits, and the problem of estimating the noncentrality parameter has been addressed. As in Parts 1-3, extensive Monte Carlo simulations were performed and all the simulation results were found to be in excellent agreement with the derived theoretical expressions. Specific recommendations for harmonization of detection limit methodology have also been made

  12. How long is enough to detect terrestrial animals? Estimating the minimum trapping effort on camera traps

    Directory of Open Access Journals (Sweden)

    Xingfeng Si

    2014-05-01

    Full Text Available Camera traps is an important wildlife inventory tool for estimating species diversity at a site. Knowing what minimum trapping effort is needed to detect target species is also important to designing efficient studies, considering both the number of camera locations, and survey length. Here, we take advantage of a two-year camera trapping dataset from a small (24-ha study plot in Gutianshan National Nature Reserve, eastern China to estimate the minimum trapping effort actually needed to sample the wildlife community. We also evaluated the relative value of adding new camera sites or running cameras for a longer period at one site. The full dataset includes 1727 independent photographs captured during 13,824 camera days, documenting 10 resident terrestrial species of birds and mammals. Our rarefaction analysis shows that a minimum of 931 camera days would be needed to detect the resident species sufficiently in the plot, and c. 8700 camera days to detect all 10 resident species. In terms of detecting a diversity of species, the optimal sampling period for one camera site was c. 40, or long enough to record about 20 independent photographs. Our analysis of evaluating the increasing number of additional camera sites shows that rotating cameras to new sites would be more efficient for measuring species richness than leaving cameras at fewer sites for a longer period.

  13. Improved detection limits for electrospray ionization on a magnetic sector mass spectrometer by using an array detector.

    Science.gov (United States)

    Cody, R B; Tamura, J; Finch, J W; Musselman, B D

    1994-03-01

    Array detection was compared with point detection for solutions of hen egg-white lysozyme, equine myoglobin, and ubiquitin analyzed by electrospray ionization with a magnetic sector mass spectrometer. The detection limits for samples analyzed by using the array detector system were at least 10 times lower than could be achieved by using a point detector on the same mass spectrometer. The minimum detectable quantity of protein corresponded to a signal-to-background ratio of approximately 2∶1 for a 500 amol/μL solution of hen egg-white lysozyme. However, the ultimate practical sample concentrations appeared to be in the 10-100 fmol/μL range for the analysis of dilute solutions of relatively pure proteins or simple mixtures.

  14. Minimum detectable activities for natural radionuclides for IRIS-XP airborne gamma-spectrometer

    International Nuclear Information System (INIS)

    Ohera, Marcel; Sladek, Petr

    2009-01-01

    To subtract the 90 Sr background in the helicopter (the 90 Sr source is used as a freezing deposit indicator in Mi-17 helicopters), a spectrum at the altitude of more than 500 metre altitude above the ground for 10 minutes was acquired. The spectra at 50, 100 and 150 m altitude were corrected for the aircraft and the cosmics, stripping and height attenuation in K, U and Th peak windows. For IRIS-XP, better results have been obtained than presented so far. The new calculated minimum detectable activities (MDAs) are 114 Bq/kg for 40 K, 16 Bq/kg for 238 U and 8 Bq/kg for 232 Th at 95% confidence interval for 1 second spectra at 100 m altitude. This work deals with counting statistics and the estimate of the MDAs for natural radionuclides for the IRIS-XP airborne gamma-ray spectrometer (4 x 4 litre NaI(Tl)) produced by PICO Envirotec, Inc. in Toronto, Canada. The detection sensitivities (MDA) for 4 x 4 NaI(Tl) crystals at the altitude of 90 m presented by Pico Envirotec, Inc. are too high compared with the detection sensitivities presented by other airborne gamma-ray spectrometer producers. This was the reason why to calculate and verify the MDA for IRIS-XP. Firstly, the minimum detectable activities for IRIS-XP for 4 x 4 litre NaI(Tl) crystals were determined based on the data acquired on the calibration pads at the Holland Landing Airport in Toronto, Canada to test the method of calculation used. This method on calibration pads provides all available window sensitivities, stripping factors and counts in the natural radionuclide windows to verify the computing method. Secondly, the MDAs under the real flight conditions were also estimated for the IRIS-XP (4 x 4 litre NaI(Tl) crystals) which was delivered to the Czech Armed Forces. The MDAs were calculated based on the data acquired during the tests at the Military Training Area in Vyskov, Czech Republic. The data was collected at three different altitudes (50 m, 100 m and 150 m) when the Mi-17 helicopter with IRIS

  15. Cellulose accessibility limits the effectiveness of minimum cellulase loading on the efficient hydrolysis of pretreated lignocellulosic substrates

    Directory of Open Access Journals (Sweden)

    Saddler Jack N

    2011-02-01

    Full Text Available Abstract A range of lignocellulosic feedstocks (including agricultural, softwood and hardwood substrates were pretreated with either sulfur dioxide-catalyzed steam or an ethanol organosolv procedure to try to establish a reliable assessment of the factors governing the minimum protein loading that could be used to achieve efficient hydrolysis. A statistical design approach was first used to define what might constitute the minimum protein loading (cellulases and β-glucosidase that could be used to achieve efficient saccharification (defined as at least 70% glucan conversion of the pretreated substrates after 72 hours of hydrolysis. The likely substrate factors that limit cellulose availability/accessibility were assessed, and then compared with the optimized minimum amounts of protein used to obtain effective hydrolysis. The optimized minimum protein loadings to achieve efficient hydrolysis of seven pretreated substrates ranged between 18 and 63 mg protein per gram of glucan. Within the similarly pretreated group of lignocellulosic feedstocks, the agricultural residues (corn stover and corn fiber required significantly lower protein loadings to achieve efficient hydrolysis than did the pretreated woody biomass (poplar, douglas fir and lodgepole pine. Regardless of the substantial differences in the source, structure and chemical composition of the feedstocks, and the difference in the pretreatment technology used, the protein loading required to achieve efficient hydrolysis of lignocellulosic substrates was strongly dependent on the accessibility of the cellulosic component of each of the substrates. We found that cellulose-rich substrates with highly accessible cellulose, as assessed by the Simons' stain method, required a lower protein loading per gram of glucan to obtain efficient hydrolysis compared with substrates containing less accessible cellulose. These results suggest that the rate-limiting step during hydrolysis is not the catalytic

  16. Minimum detectable activities of contamination control survey equipment

    International Nuclear Information System (INIS)

    Goles, R.W.; Baumann, B.L.; Johnson, M.L.

    1991-08-01

    The Instrumentation ampersand External Dosimetry (I ampersand ED) Section of the Health Physics Department at the Pacific Northwest Laboratory (PNL) has performed a series of tests to determine the ability of portable survey instruments used at Hanford to detect radioactive contamination at levels required by DOE 5480.11. This semi-empirical study combines instrumental, statistical, and human factors as necessary to derive operational detection limits. These threshold detection values have been compared to existing contamination control requirements, and detection deficiencies have been identified when present. Portable survey instruments used on the Hanford Site identify the presence of radioactive surface contamination based on the detection of α-, β-, γ-, and/or x-radiation. However, except in some unique circumstances, most contamination monitors in use at Hanford are configured to detect either α-radiation alone or β- and γ-radiation together. Testing was therefore conducted on only these two categories of radiation detection devices. Nevertheless, many of the results obtained are generally applicable to all survey instruments, allowing performance evaluations to be extended to monitoring devices which are exclusively γ- and/or x-ray- sensitive. 6 figs., 2 tabs

  17. Detection limit calculations for different total reflection techniques

    International Nuclear Information System (INIS)

    Sanchez, H.J.

    2000-01-01

    In this work, theoretical calculations of detection limits for different total-reflection techniques are presented.. Calculations include grazing incidence (TXRF) and gracing exit (GEXRF) conditions. These calculations are compared with detection limits obtained for conventional x-ray fluorescence (XRF). In order to compute detection limits the Shiraiwa and Fujino's model to calculate x-ray fluorescence intensities was used. This model made certain assumptions and approximations to achieve the calculations, specially in the case of the geometrical conditions of the sample, and the incident and takeoff beams. Nevertheless the calculated data of detection limits for conventional XRF and total-reflection XRF show a good agreement with previous results. The model proposed here allows to analyze the different sources of background and the influence of the excitation geometry, which contribute to the understanding of the physical processes involved in the XRF analysis by total reflection. Finally, a comparison between detection limits in total-reflection analysis at grazing incidence and at grazing exit is carried out. Here a good agreement with the theoretical predictions of the reversibility principle is found, showing that detection limits are similar for both techniques. (author)

  18. PROBABILITY CALIBRATION BY THE MINIMUM AND MAXIMUM PROBABILITY SCORES IN ONE-CLASS BAYES LEARNING FOR ANOMALY DETECTION

    Data.gov (United States)

    National Aeronautics and Space Administration — PROBABILITY CALIBRATION BY THE MINIMUM AND MAXIMUM PROBABILITY SCORES IN ONE-CLASS BAYES LEARNING FOR ANOMALY DETECTION GUICHONG LI, NATHALIE JAPKOWICZ, IAN HOFFMAN,...

  19. Cs2AgBiBr6 single-crystal X-ray detectors with a low detection limit

    Science.gov (United States)

    Pan, Weicheng; Wu, Haodi; Luo, Jiajun; Deng, Zhenzhou; Ge, Cong; Chen, Chao; Jiang, Xiaowei; Yin, Wan-Jian; Niu, Guangda; Zhu, Lujun; Yin, Lixiao; Zhou, Ying; Xie, Qingguo; Ke, Xiaoxing; Sui, Manling; Tang, Jiang

    2017-11-01

    Sensitive X-ray detection is crucial for medical diagnosis, industrial inspection and scientific research. The recently described hybrid lead halide perovskites have demonstrated low-cost fabrication and outstanding performance for direct X-ray detection, but they all contain toxic Pb in a soluble form. Here, we report sensitive X-ray detectors using solution-processed double perovskite Cs2AgBiBr6 single crystals. Through thermal annealing and surface treatment, we largely eliminate Ag+/Bi3+ disordering and improve the crystal resistivity, resulting in a detector with a minimum detectable dose rate as low as 59.7 nGyair s-1, comparable to the latest record of 0.036 μGyair s-1 using CH3NH3PbBr3 single crystals. Suppressed ion migration in Cs2AgBiBr6 permits relatively large external bias, guaranteeing efficient charge collection without a substantial increase in noise current and thus enabling the low detection limit.

  20. Activation analysis. Detection limits

    International Nuclear Information System (INIS)

    Revel, G.

    1999-01-01

    Numerical data and limits of detection related to the four irradiation modes, often used in activation analysis (reactor neutrons, 14 MeV neutrons, photon gamma and charged particles) are presented here. The technical presentation of the activation analysis is detailed in the paper P 2565 of Techniques de l'Ingenieur. (A.L.B.)

  1. Probe-Specific Procedure to Estimate Sensitivity and Detection Limits for 19F Magnetic Resonance Imaging.

    Directory of Open Access Journals (Sweden)

    Alexander J Taylor

    Full Text Available Due to low fluorine background signal in vivo, 19F is a good marker to study the fate of exogenous molecules by magnetic resonance imaging (MRI using equilibrium nuclear spin polarization schemes. Since 19F MRI applications require high sensitivity, it can be important to assess experimental feasibility during the design stage already by estimating the minimum detectable fluorine concentration. Here we propose a simple method for the calibration of MRI hardware, providing sensitivity estimates for a given scanner and coil configuration. An experimental "calibration factor" to account for variations in coil configuration and hardware set-up is specified. Once it has been determined in a calibration experiment, the sensitivity of an experiment or, alternatively, the minimum number of required spins or the minimum marker concentration can be estimated without the need for a pilot experiment. The definition of this calibration factor is derived based on standard equations for the sensitivity in magnetic resonance, yet the method is not restricted by the limited validity of these equations, since additional instrument-dependent factors are implicitly included during calibration. The method is demonstrated using MR spectroscopy and imaging experiments with different 19F samples, both paramagnetically and susceptibility broadened, to approximate a range of realistic environments.

  2. Probe-Specific Procedure to Estimate Sensitivity and Detection Limits for 19F Magnetic Resonance Imaging.

    Science.gov (United States)

    Taylor, Alexander J; Granwehr, Josef; Lesbats, Clémentine; Krupa, James L; Six, Joseph S; Pavlovskaya, Galina E; Thomas, Neil R; Auer, Dorothee P; Meersmann, Thomas; Faas, Henryk M

    2016-01-01

    Due to low fluorine background signal in vivo, 19F is a good marker to study the fate of exogenous molecules by magnetic resonance imaging (MRI) using equilibrium nuclear spin polarization schemes. Since 19F MRI applications require high sensitivity, it can be important to assess experimental feasibility during the design stage already by estimating the minimum detectable fluorine concentration. Here we propose a simple method for the calibration of MRI hardware, providing sensitivity estimates for a given scanner and coil configuration. An experimental "calibration factor" to account for variations in coil configuration and hardware set-up is specified. Once it has been determined in a calibration experiment, the sensitivity of an experiment or, alternatively, the minimum number of required spins or the minimum marker concentration can be estimated without the need for a pilot experiment. The definition of this calibration factor is derived based on standard equations for the sensitivity in magnetic resonance, yet the method is not restricted by the limited validity of these equations, since additional instrument-dependent factors are implicitly included during calibration. The method is demonstrated using MR spectroscopy and imaging experiments with different 19F samples, both paramagnetically and susceptibility broadened, to approximate a range of realistic environments.

  3. Minimum variance and variance of outgoing quality limit MDS-1(c1, c2) plans

    Science.gov (United States)

    Raju, C.; Vidya, R.

    2016-06-01

    In this article, the outgoing quality (OQ) and total inspection (TI) of multiple deferred state sampling plans MDS-1(c1,c2) are studied. It is assumed that the inspection is rejection rectification. Procedures for designing MDS-1(c1,c2) sampling plans with minimum variance of OQ and TI are developed. A procedure for obtaining a plan for a designated upper limit for the variance of the OQ (VOQL) is outlined.

  4. How low can you go? Assessing minimum concentrations of NSC in carbon limited tree saplings

    Science.gov (United States)

    Hoch, Guenter; Hartmann, Henrik; Schwendener, Andrea

    2016-04-01

    Tissue concentrations of non-structural carbohydrates (NSC) are frequently used to determine the carbon balance of plants. Over the last years, an increasing number of studies have inferred carbon starvation in trees under environmental stress like drought from low tissue NSC concentrations. However, such inferences are limited by the fact that minimum concentrations of NSC required for survival are not known. So far, it was hypothesized that even under lethal carbon starvation, starch and low molecular sugar concentrations cannot be completely depleted and that minimum NSC concentrations at death vary across tissues and species. Here we present results of an experiment that aimed to determine minimum NSC concentrations in different tissues of saplings of two broad-leaved tree species (Acer pseudoplatanus and Quercus petratea) exposed to lethal carbon starvation via continuous darkening. In addition, we investigated recovery rates of NSC concentrations in saplings that had been darkened for different periods of time and were then re-exposed to light. Both species survived continuous darkening for about 12 weeks (confirmed by testing the ability to re-sprout after darkness). In all investigated tissues, starch concentrations declined close to zero within three to six weeks of darkness. Low molecular sugars also decreased strongly within the first weeks of darkness, but seemed to stabilize at low concentrations of 0.5 to 2 % dry matter (depending on tissue and species) almost until death. NSC concentrations recovered surprisingly fast in saplings that were re-exposed to light. After 3 weeks of continuous darkness, tissue NSC concentrations recovered within 6 weeks to levels of unshaded control saplings in all tissues and in both species. To our knowledge, this study represents the first experimental attempt to quantify minimum tissue NSC concentrations at lethal carbon starvation. Most importantly, our results suggest that carbon-starved tree saplings are able to

  5. Establishment of limits of detection and decision

    International Nuclear Information System (INIS)

    Mende, O.; Michel, R.

    1995-01-01

    The purpose of this project was to develop and test procedures to establish limits of decision and detection for spectrometric nuclear radiation measurements. Beside the determination of the limits of application of DIN 25482 part 2 and 5 - both primarily suitable for high resoluted spectra areas -the statistical model was expanded in such a way that henceforth blanks and influences of sample treatment can also be taken into account; the corresponding procedures to calculate the limits of decision and detection have a high precision. Additional procedures of calculation were developed to take the special characteristics of the analysis of complex spectra areas into account. (orig.) [de

  6. ON COMPUTING UPPER LIMITS TO SOURCE INTENSITIES

    International Nuclear Information System (INIS)

    Kashyap, Vinay L.; Siemiginowska, Aneta; Van Dyk, David A.; Xu Jin; Connors, Alanna; Freeman, Peter E.; Zezas, Andreas

    2010-01-01

    A common problem in astrophysics is determining how bright a source could be and still not be detected in an observation. Despite the simplicity with which the problem can be stated, the solution involves complicated statistical issues that require careful analysis. In contrast to the more familiar confidence bound, this concept has never been formally analyzed, leading to a great variety of often ad hoc solutions. Here we formulate and describe the problem in a self-consistent manner. Detection significance is usually defined by the acceptable proportion of false positives (background fluctuations that are claimed as detections, or Type I error), and we invoke the complementary concept of false negatives (real sources that go undetected, or Type II error), based on the statistical power of a test, to compute an upper limit to the detectable source intensity. To determine the minimum intensity that a source must have for it to be detected, we first define a detection threshold and then compute the probabilities of detecting sources of various intensities at the given threshold. The intensity that corresponds to the specified Type II error probability defines that minimum intensity and is identified as the upper limit. Thus, an upper limit is a characteristic of the detection procedure rather than the strength of any particular source. It should not be confused with confidence intervals or other estimates of source intensity. This is particularly important given the large number of catalogs that are being generated from increasingly sensitive surveys. We discuss, with examples, the differences between these upper limits and confidence bounds. Both measures are useful quantities that should be reported in order to extract the most science from catalogs, though they answer different statistical questions: an upper bound describes an inference range on the source intensity, while an upper limit calibrates the detection process. We provide a recipe for computing upper

  7. Working with Detection Limits in X-Ray and Nuclear Spectrometry

    International Nuclear Information System (INIS)

    Van Espen, P.

    2003-01-01

    Full Text: Detection limits are important in many measurement procedures. Especially in analytical work we often need to take a decision about the presence or absence of a compound, or we need to guarantee that or instrument can detect the compound. Especially in regulatory work the concept of detection limits plays a crucial role. Data acquisition in x-ray and gamma-ray spectrometry is done by counting events for a preset time; hence the fluctuations in the observed spectra are governed by Poisson (counting) statistics. This makes the calculation of detection limits in principle very easy. However it is observed that there exists a great deal of confusion concerning the definition(s) and especially concerning the practical calculation and reporting of detection limits. In this contribution a simple but rigorous treatment of the concept of detection limits will be given, emphasizing on aspects such as a-priori and a-posterior i limits and on the effect of sample blank and instrumental blank in the calculation of the true detection limit. The problem of near zero background as observed in e.g. total reflection x-ray fluorescence analysis (T-XRF) and some low level counting applications will also be discussed. In this case Poisson statistics might not be applicable, affecting the decision limits with respect to the presence of absence of a signal. Finally handling data sets that contain detection limit values next to normal measured values, the so called problem of missing data will be discussed. Some suggestions to deal with this frequently occurring situation will be given

  8. Limits of qualitative detection and quantitative determination

    International Nuclear Information System (INIS)

    Curie, L.A.

    1976-01-01

    The fact that one can find a series of disagreeing and limiting definitions of the detection limit leads to the reinvestigation of the problems of signal detection and signal processing in analytical and nuclear chemistry. Three cut-off levels were fixed: Lsub(C) - the net signal level (sensitivity of the equipment), above which an observed signal can be reliably recognized as 'detected'; Lsub(D) - the 'true' net signal level, from which one can a priori expect a detection; Lsub(Q) - the level at which the measuring accuracy is sufficient for quantitative determination. Exact definition equations as well as a series of working formulae are given for the general analytical case and for the investigation of radioactivity. As it is assumed that the radioactivity of the Poisson distribution is determined, it is dealt with in such a manner that precise limits can be derived for short-lived and long-lived radionuclides with or without disturbance. The fundamentals are made clear by simple examples for spectrophotometry and radioactivity and by a complicated example for activation analysis in which one must choose between alternative nuclear reactions. (orig./LH) [de

  9. On the lower of limit detection of radiometric systems

    International Nuclear Information System (INIS)

    Kamburov, H.; Boneva, S.

    1983-01-01

    The existing definitions of the quantity Asub(min), the lower detection limit, introduced as a characteristic of the sensitivity of radiometric systems are reviewed. A convenient way is found for comparing the different definitions by showing that each definition is connected with a specific value of the probability a of Type I error. The detection limits are calculated for a normal and Poisson distributions of the measured quantities. A criterion is proposed for the applicability of the normal distiribution to the problem of determining the lower detection limit

  10. Determination of detection limits for a VPD ICPMS method of analysis; Determination des limites de detection d'une methode d'analyse VPD ICPMS

    Energy Technology Data Exchange (ETDEWEB)

    Badard, M.; Veillerot, M

    2007-07-01

    This training course report presents the different methods of detection and quantifying of metallic impurities in semiconductors. One of the most precise technique is the collection of metal impurities by vapor phase decomposition (VPD) followed by their analysis by ICPMS (inductively coupled plasma mass spectrometry). The study shows the importance of detection limits in the domain of chemical analysis and the way to determine them for the ICPMS analysis. The results found on detection limits are excellent. Even if the detection limits reached with ICPMS performed after manual or automatic VPD are much higher than detection limits of ICPMS alone, this method remains one of the most sensible for ultra-traces analysis. (J.S.)

  11. Detection Limits Of The 125I Air Sampler ''RIS125''

    International Nuclear Information System (INIS)

    Belaish, I.; Levinson, S.; German, U.; Kravchik, T.

    1999-01-01

    A system for 125 I monitoring in air (RIS-125) was designed and manufactured at NRCN. The main features of the system are described elsewhere. The system can monitor 125 I air contamination in gaseous and aerosol forms. An air monitoring system should have a fast response and the lowest available Minimum Detectable Activity (MDA). The present work presents the characteristic MDA values of the system

  12. Limits of Tumor Detectability in Nuclear Medicine and PET

    Directory of Open Access Journals (Sweden)

    Yusuf Emre Erdi

    2012-04-01

    Full Text Available Objective: Nuclear medicine is becoming increasingly important in the early detection of malignancy. The advantage of nuclear medicine over other imaging modalities is the high sensitivity of the gamma camera. Nuclear medicine counting equipment has the capability of detecting levels of radioactivity which exceed background levels by as little as 2.4 to 1. This translates to only a few hundred counts per minute on a regular gamma camera or as few as 3 counts per minute when using coincidence detection on a positron emission tomography (PET camera. Material and Methods: We have experimentally measured the limits of detectability using a set of hollow spheres in a Jaszczak phantom at various tumor-to-background ratios. Imaging modalities for this work were (1 planar, (2 SPECT, (3 PET, and (4 planar camera with coincidence detection capability (MCD. Results: When there is no background (infinite contrast activity present, the detectability of tumors is similar for PET and planar imaging. With the presence of the background activity , PET can detect objects in an order of magnitude smaller in size than that can be seen by conventional planar imaging especially in the typical clinical low (3:1 T/B ratios. The detection capability of the MCD camera lies between a conventional nuclear medicine (planar / SPECT scans and the detection capability of a dedicated PET scanner Conclusion: Among nuclear medicine’s armamentarium, PET is the closest modality to CT or MR imaging in terms of limits of detection. Modern clinical PET scanners have a resolution limit of 4 mm, corresponding to the detection of tumors with a volume of 0.2 ml (7 mm diameter in 5:1 T/B ratio. It is also possible to obtain better resolution limits with dedicated brain and animal scanners. The future holds promise in development of new detector materials, improved camera design, and new reconstruction algorithms which will improve sensitivity, resolution, contrast, and thereby further

  13. Quantifying environmental limiting factors on tree cover using geospatial data.

    Science.gov (United States)

    Greenberg, Jonathan A; Santos, Maria J; Dobrowski, Solomon Z; Vanderbilt, Vern C; Ustin, Susan L

    2015-01-01

    Environmental limiting factors (ELFs) are the thresholds that determine the maximum or minimum biological response for a given suite of environmental conditions. We asked the following questions: 1) Can we detect ELFs on percent tree cover across the eastern slopes of the Lake Tahoe Basin, NV? 2) How are the ELFs distributed spatially? 3) To what extent are unmeasured environmental factors limiting tree cover? ELFs are difficult to quantify as they require significant sample sizes. We addressed this by using geospatial data over a relatively large spatial extent, where the wall-to-wall sampling ensures the inclusion of rare data points which define the minimum or maximum response to environmental factors. We tested mean temperature, minimum temperature, potential evapotranspiration (PET) and PET minus precipitation (PET-P) as potential limiting factors on percent tree cover. We found that the study area showed system-wide limitations on tree cover, and each of the factors showed evidence of being limiting on tree cover. However, only 1.2% of the total area appeared to be limited by the four (4) environmental factors, suggesting other unmeasured factors are limiting much of the tree cover in the study area. Where sites were near their theoretical maximum, non-forest sites (tree cover demand, and closed-canopy forests were not limited by any particular environmental factor. The detection of ELFs is necessary in order to fully understand the width of limitations that species experience within their geographic range.

  14. Determination of limits for smallest detectable and largest subcritical leakage cracks in piping systems

    International Nuclear Information System (INIS)

    Bieselt, R.; Wolf, M.

    1995-01-01

    Nuclear power plant piping systems - those still in their original as-built condition as well as upgraded designs - are subject to safety analysis. In order to limit the consequences of postulated piping failures, the basic safety concept incorporating rupture preclusion criteria is applied to specific high-energy piping systems. Leak-before-break analyses are also conducted within the framework of this concept. These analyses serve to determine the potential consequences of jet and reaction forces due to maximum subcritical leakage cracks while also establishing the minimum crack sizes that would be reliably detectable by the leakage rates resulting from these cracks. The boundary conditions for these analyses are not clearly defined. Using various examples as a basis, this paper presents and discusses how the leak-before-break concept can be applied. (orig.)

  15. Search times and probability of detection in time-limited search

    Science.gov (United States)

    Wilson, David; Devitt, Nicole; Maurer, Tana

    2005-05-01

    When modeling the search and target acquisition process, probability of detection as a function of time is important to war games and physical entity simulations. Recent US Army RDECOM CERDEC Night Vision and Electronics Sensor Directorate modeling of search and detection has focused on time-limited search. Developing the relationship between detection probability and time of search as a differential equation is explored. One of the parameters in the current formula for probability of detection in time-limited search corresponds to the mean time to detect in time-unlimited search. However, the mean time to detect in time-limited search is shorter than the mean time to detect in time-unlimited search and the relationship between them is a mathematical relationship between these two mean times. This simple relationship is derived.

  16. Feedback damping of a microcantilever at room temperature to the minimum vibration amplitude limited by the noise level.

    Science.gov (United States)

    Kawamura, Y; Kanegae, R

    2016-06-17

    Cooling the vibration amplitude of a microcantilever as low as possible is important to improve the sensitivity and resolutions of various types of scanning type microscopes and sensors making use of it. When the vibration amplitude is controlled to be smaller using a feed back control system, it is known that the obtainable minimum amplitude of the vibration is limited by the floor noise level of the detection system. In this study, we demonstrated that the amplitude of the thermal vibration of a microcantilever was suppressed to be about 0.15 pmHz(-1/2), which is the same value with the floor noise level, without the assistance of external cryogenic cooling. We think that one of the reason why we could reach the smaller amplitude at room temperature is due to stiffer spring constant of the lever, which leads to higher natural frequency and consequently lower floor noise level. The other reason is considered to be due to the increase in the laser power for the diagnostics, which lead to the decrease in the signal to noise ratio determined by the optical shot noise.

  17. 40 CFR Table 11 to Subpart Xxxx of... - Minimum Data for Continuous Compliance With the Emission Limits for Tire Cord Production Affected...

    Science.gov (United States)

    2010-07-01

    ... With the Emission Limits for Tire Cord Production Affected Sources 11 Table 11 to Subpart XXXX of Part... for Hazardous Air Pollutants: Rubber Tire Manufacturing Pt. 63, Subpt. XXXX, Table 11 Table 11 to Subpart XXXX of Part 63—Minimum Data for Continuous Compliance With the Emission Limits for Tire Cord...

  18. Methodologies for the practical determination and use of method detection limits

    International Nuclear Information System (INIS)

    Rucker, T.L.

    1995-01-01

    Method detection limits have often been misunderstood and misused. The basic definitions developed by Lloyd Currie and others have been combined with assumptions that are inappropriate for many types of radiochemical analyses. A partical way for determining detection limits based on Currie's basic definition is presented that removes the reliance on assumptions and that accounts for the total measurement uncertainty. Examples of proper and improper use of detection limits are also presented, including detection limits reported by commercial software for gamma spectroscopy and neutron activation analyses. (author) 6 refs.; 2 figs

  19. No evidence for an item limit in change detection.

    Directory of Open Access Journals (Sweden)

    Shaiyan Keshvari

    Full Text Available Change detection is a classic paradigm that has been used for decades to argue that working memory can hold no more than a fixed number of items ("item-limit models". Recent findings force us to consider the alternative view that working memory is limited by the precision in stimulus encoding, with mean precision decreasing with increasing set size ("continuous-resource models". Most previous studies that used the change detection paradigm have ignored effects of limited encoding precision by using highly discriminable stimuli and only large changes. We conducted two change detection experiments (orientation and color in which change magnitudes were drawn from a wide range, including small changes. In a rigorous comparison of five models, we found no evidence of an item limit. Instead, human change detection performance was best explained by a continuous-resource model in which encoding precision is variable across items and trials even at a given set size. This model accounts for comparison errors in a principled, probabilistic manner. Our findings sharply challenge the theoretical basis for most neural studies of working memory capacity.

  20. 40 CFR Table 13 to Subpart Xxxx of... - Minimum Data for Continuous Compliance With the Emission Limitations for Puncture Sealant...

    Science.gov (United States)

    2010-07-01

    ... XXXX of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... Standards for Hazardous Air Pollutants: Rubber Tire Manufacturing Pt. 63, Subpt. XXXX, Table 13 Table 13 to Subpart XXXX of Part 63—Minimum Data for Continuous Compliance With the Emission Limitations for Puncture...

  1. Determination of detection limits for a VPD ICPMS method of analysis

    International Nuclear Information System (INIS)

    Badard, M.; Veillerot, M.

    2007-01-01

    This training course report presents the different methods of detection and quantifying of metallic impurities in semiconductors. One of the most precise technique is the collection of metal impurities by vapor phase decomposition (VPD) followed by their analysis by ICPMS (inductively coupled plasma mass spectrometry). The study shows the importance of detection limits in the domain of chemical analysis and the way to determine them for the ICPMS analysis. The results found on detection limits are excellent. Even if the detection limits reached with ICPMS performed after manual or automatic VPD are much higher than detection limits of ICPMS alone, this method remains one of the most sensible for ultra-traces analysis. (J.S.)

  2. Quantifying environmental limiting factors on tree cover using geospatial data.

    Directory of Open Access Journals (Sweden)

    Jonathan A Greenberg

    Full Text Available Environmental limiting factors (ELFs are the thresholds that determine the maximum or minimum biological response for a given suite of environmental conditions. We asked the following questions: 1 Can we detect ELFs on percent tree cover across the eastern slopes of the Lake Tahoe Basin, NV? 2 How are the ELFs distributed spatially? 3 To what extent are unmeasured environmental factors limiting tree cover? ELFs are difficult to quantify as they require significant sample sizes. We addressed this by using geospatial data over a relatively large spatial extent, where the wall-to-wall sampling ensures the inclusion of rare data points which define the minimum or maximum response to environmental factors. We tested mean temperature, minimum temperature, potential evapotranspiration (PET and PET minus precipitation (PET-P as potential limiting factors on percent tree cover. We found that the study area showed system-wide limitations on tree cover, and each of the factors showed evidence of being limiting on tree cover. However, only 1.2% of the total area appeared to be limited by the four (4 environmental factors, suggesting other unmeasured factors are limiting much of the tree cover in the study area. Where sites were near their theoretical maximum, non-forest sites (tree cover < 25% were primarily limited by cold mean temperatures, open-canopy forest sites (tree cover between 25% and 60% were primarily limited by evaporative demand, and closed-canopy forests were not limited by any particular environmental factor. The detection of ELFs is necessary in order to fully understand the width of limitations that species experience within their geographic range.

  3. Computation of distribution of minimum resolution for log-normal distribution of chromatographic peak heights.

    Science.gov (United States)

    Davis, Joe M

    2011-10-28

    General equations are derived for the distribution of minimum resolution between two chromatographic peaks, when peak heights in a multi-component chromatogram follow a continuous statistical distribution. The derivation draws on published theory by relating the area under the distribution of minimum resolution to the area under the distribution of the ratio of peak heights, which in turn is derived from the peak-height distribution. Two procedures are proposed for the equations' numerical solution. The procedures are applied to the log-normal distribution, which recently was reported to describe the distribution of component concentrations in three complex natural mixtures. For published statistical parameters of these mixtures, the distribution of minimum resolution is similar to that for the commonly assumed exponential distribution of peak heights used in statistical-overlap theory. However, these two distributions of minimum resolution can differ markedly, depending on the scale parameter of the log-normal distribution. Theory for the computation of the distribution of minimum resolution is extended to other cases of interest. With the log-normal distribution of peak heights as an example, the distribution of minimum resolution is computed when small peaks are lost due to noise or detection limits, and when the height of at least one peak is less than an upper limit. The distribution of minimum resolution shifts slightly to lower resolution values in the first case and to markedly larger resolution values in the second one. The theory and numerical procedure are confirmed by Monte Carlo simulation. Copyright © 2011 Elsevier B.V. All rights reserved.

  4. Minimum Delay Moving Object Detection

    KAUST Repository

    Lao, Dong; Sundaramoorthi, Ganesh

    2017-01-01

    We present a general framework and method for detection of an object in a video based on apparent motion. The object moves relative to background motion at some unknown time in the video, and the goal is to detect and segment the object as soon

  5. Importance of the lower limit of detection in radiological safety

    International Nuclear Information System (INIS)

    Rafael Terol T.; Hermenegildo Maldonado M.

    1991-01-01

    The concept of the Lower Limit of Detection (LLD) it contributes in the solution of some problems related with the radiological safety, such as the realization of the tests of flight of the sealed radioactive sources; the determination of radioisotopes in environmental samples; the estimate of present radionuclides in polluted foods; in general, the detection of small quantities of radioactive materials present in materials of use or consumption by part of the man in his daily life; as the one Lower Limit of Detection is related with topics of statistics, in this work a small review of them is made, it was superficially discussed the mensuration problems related with the establishment of the Lower Limit of Detection

  6. Confirmation of identity and detection limit in neutron activation analysis

    International Nuclear Information System (INIS)

    Yustina Tri Handayani; Slamet Wiyuniati; Tulisna

    2010-01-01

    Neutron Activation Analysis (NAA) based on neutron capture by nuclides. Of the various possibilities of radionuclides that occur, radionuclides and gamma radiation which provides the identity of the element were analyzed and the best sensitivity should be determined. Confirmation for elements in sediment samples was done theoretically and experimentally. The result of confirmation shows that Al, V, Cr K, Na, Ca and Zn were analyzed based on radionuclides of Al-28, V-52, Cr-51 , K-42, Na-24, Ca-48, Zn-65. Elements of Mg, Mn, Fe, Co were analyzed based on radionuclides of Mg-27, Mn-56, Fe-59, Co-60 through peak which the highest value of combined probability of radiation emission and efficiency. Cu can be analyzed through Cu-64 or Cu-66, but the second is more sensitive. Detection limit is determined at a certain measurement conditions carried out by a laboratory. Detection limit in the NAA is determined based on the Compton continue area by Curie method. The detection limit of Al, V, Ca, Mg, Mn, As, K, Na, Mg, Ce, Co, Cr, Fe, La, Sc, and Zn in sediment samples are 240, 27, 4750, 2600, 21, 3.3 , 75, 1.4, 1.8, 0.5, 2.7, 29, 1, 0.05, and 37 ppm. Analysis of Cu in sediments which concentrations of 98.6 ppm, Cu-66 is not detected. Tests using pure standard solutions of Cu obtained detection limit of 0.12 µg, or 7.9 ppm in samples of 15 mg. In general, the detection limit obtained was higher than the detection limit of the reference, it was caused by the differences in the sample matrix and analytical conditions. (author)

  7. Stochastic fluctuations and the detectability limit of network communities.

    Science.gov (United States)

    Floretta, Lucio; Liechti, Jonas; Flammini, Alessandro; De Los Rios, Paolo

    2013-12-01

    We have analyzed the detectability limits of network communities in the framework of the popular Girvan and Newman benchmark. By carefully taking into account the inevitable stochastic fluctuations that affect the construction of each and every instance of the benchmark, we come to the conclusion that the native, putative partition of the network is completely lost even before the in-degree/out-degree ratio becomes equal to that of a structureless Erdös-Rényi network. We develop a simple iterative scheme, analytically well described by an infinite branching process, to provide an estimate of the true detectability limit. Using various algorithms based on modularity optimization, we show that all of them behave (semiquantitatively) in the same way, with the same functional form of the detectability threshold as a function of the network parameters. Because the same behavior has also been found by further modularity-optimization methods and for methods based on different heuristics implementations, we conclude that indeed a correct definition of the detectability limit must take into account the stochastic fluctuations of the network construction.

  8. Optimum allocation of imaging time and minimum detectable activity in dual isotope blood pool subtraction indium-111 platelet imaging

    International Nuclear Information System (INIS)

    Machac, J.; Horowitz, S.F.; Goldsmith, S.J.; Fuster, V.

    1984-01-01

    Indium-111 labeled platelet imaging is a tool for detection of thrombus formation in vascular spaces. Dual isotope blood pool subtraction may help differentiate focal platelet accumulation from blood pool activity. This study used a computer model to calculate the minimum excess-to-blood pool platelet ratio (EX/BP) and the optimum dual isotope imaging times under varied conditions of lesion size. The model simulated usual human imaging doses of 500 μCi of In-111 platelets and 5mCi of Tc-99m labeled RBCs giving a reference cardiac blood pool region (100cc) of 10000 cpm for Tc-99m and 500 cpm for In-111. The total imaging time was fixed at 20 minutes, while the two isotope imaging times (TIn/TTc) were varied, as were the simulated lesion size (cc) and EX/BP. The relative error of the excess counts was calculated using propagation of error theory. At the critical level of detection, where the excess lesion counts equal 3 times the standard deviation, the optimum TIn/TTc and minimum Ex/BP were determined for each lesion size. For the smallest lesion size (0.1cc), the minimum detectable EX/BP ratio was 1.6, with the best TIn/TTC ratio of 18/2 minutes, and for large lesions, an EX/BP of 0.1, with a TIn/TTc of 16/4. This model provides an estimate of the sensitivity and optimizes imaging times in dual isotope subtraction platelet imaging. The model is adaptable to varying isotope doses, total imaging times and lesion size. This information will be helpful in future in- vivo imaging studies of intravascular thrombi in humans

  9. Pushing the limits of NAA. Accuracy, uncertainty and detection limits

    International Nuclear Information System (INIS)

    Greenberg, R.R.

    2008-01-01

    This paper describes some highlights from the author's efforts to improve neutron activation analysis (NAA) detection limits through development and optimization of radiochemical separations, as well as to improve the overall accuracy of NAA measurements by identifying, quantifying and reducing measurement biases and uncertainties. Efforts to demonstrate the metrological basis of NAA, and to establish it as a 'Primary Method of Measurement' will be discussed. (author)

  10. What value, detection limits

    International Nuclear Information System (INIS)

    Currie, L.A.

    1986-01-01

    Specific approaches and applications of LLD's to nuclear and ''nuclear-related'' measurements are presented in connection with work undertaken for the U.S. Nuclear Regulatory Commission and the International Atomic Energy Agency. In this work, special attention was given to assumptions and potential error sources, as well as to different types of analysis. For the former, the authors considered random and systematic error associated with the blank and the calibration and sample preparation processes, as well as issues relating to the nature of the random error distributions. Analysis types considered included continuous monitoring, ''simple counting'' involving scalar quantities, and spectrum fitting involving data vectors. The investigation of data matrices and multivariate analysis is also described. The most important conclusions derived from this study are: that there is a significant lack of communication and compatibility resulting from diverse terminology and conceptual bases - including no-basis ''ad hoc'' definitions; that the distinction between detection decisions and detection limits is frequently lost sight of; and that quite erroneous LOD estimates follow from inadequate consideration of the actual variability of the blank, and systematic error associated with the blank, the calibration-recovery factor, matrix effects, and ''black box'' data reduction models

  11. The limit of detection for explosives in spectroscopic differential reflectometry

    Science.gov (United States)

    Dubroca, Thierry; Vishwanathan, Karthik; Hummel, Rolf E.

    2011-05-01

    In the wake of recent terrorist attacks, such as the 2008 Mumbai hotel explosion or the December 25th 2009 "underwear bomber", our group has developed a technique (US patent #7368292) to apply differential reflection spectroscopy to detect traces of explosives. Briefly, light (200-500 nm) is shone on a surface such as a piece of luggage at an airport. Upon reflection, the light is collected with a spectrometer combined with a CCD camera. A computer processes the data and produces in turn a differential reflection spectrum involving two adjacent areas of the surface. This differential technique is highly sensitive and provides spectroscopic data of explosives. As an example, 2,4,6, trinitrotoluene (TNT) displays strong and distinct features in differential reflectograms near 420 nm. Similar, but distinctly different features are observed for other explosives. One of the most important criteria for explosive detection techniques is the limit of detection. This limit is defined as the amount of explosive material necessary to produce a signal to noise ratio of three. We present here, a method to evaluate the limit of detection of our technique. Finally, we present our sample preparation method and experimental set-up specifically developed to measure the limit of detection for our technology. This results in a limit ranging from 100 nano-grams to 50 micro-grams depending on the method and the set-up parameters used, such as the detector-sample distance.

  12. Acoustic observation of living organisms reveals the upper limit of the oxygen minimum zone.

    Directory of Open Access Journals (Sweden)

    Arnaud Bertrand

    Full Text Available BACKGROUND: Oxygen minimum zones (OMZs are expanding in the World Ocean as a result of climate change and direct anthropogenic influence. OMZ expansion greatly affects biogeochemical processes and marine life, especially by constraining the vertical habitat of most marine organisms. Currently, monitoring the variability of the upper limit of the OMZs relies on time intensive sampling protocols, causing poor spatial resolution. METHODOLOGY/PRINCIPAL FINDINGS: Using routine underwater acoustic observations of the vertical distribution of marine organisms, we propose a new method that allows determination of the upper limit of the OMZ with a high precision. Applied in the eastern South-Pacific, this original sampling technique provides high-resolution information on the depth of the upper OMZ allowing documentation of mesoscale and submesoscale features (e.g., eddies and filaments that structure the upper ocean and the marine ecosystems. We also use this information to estimate the habitable volume for the world's most exploited fish, the Peruvian anchovy (Engraulis ringens. CONCLUSIONS/SIGNIFICANCE: This opportunistic method could be implemented on any vessel geared with multi-frequency echosounders to perform comprehensive high-resolution monitoring of the upper limit of the OMZ. Our approach is a novel way of studying the impact of physical processes on marine life and extracting valid information about the pelagic habitat and its spatial structure, a crucial aspect of Ecosystem-based Fisheries Management in the current context of climate change.

  13. Design for minimum energy in interstellar communication

    Science.gov (United States)

    Messerschmitt, David G.

    2015-02-01

    Microwave digital communication at interstellar distances is the foundation of extraterrestrial civilization (SETI and METI) communication of information-bearing signals. Large distances demand large transmitted power and/or large antennas, while the propagation is transparent over a wide bandwidth. Recognizing a fundamental tradeoff, reduced energy delivered to the receiver at the expense of wide bandwidth (the opposite of terrestrial objectives) is advantageous. Wide bandwidth also results in simpler design and implementation, allowing circumvention of dispersion and scattering arising in the interstellar medium and motion effects and obviating any related processing. The minimum energy delivered to the receiver per bit of information is determined by cosmic microwave background alone. By mapping a single bit onto a carrier burst, the Morse code invented for the telegraph in 1836 comes closer to this minimum energy than approaches used in modern terrestrial radio. Rather than the terrestrial approach of adding phases and amplitudes increases information capacity while minimizing bandwidth, adding multiple time-frequency locations for carrier bursts increases capacity while minimizing energy per information bit. The resulting location code is simple and yet can approach the minimum energy as bandwidth is expanded. It is consistent with easy discovery, since carrier bursts are energetic and straightforward modifications to post-detection pattern recognition can identify burst patterns. Time and frequency coherence constraints leading to simple signal discovery are addressed, and observations of the interstellar medium by transmitter and receiver constrain the burst parameters and limit the search scope.

  14. Detection of colloidal silver chloride near solubility limit

    Science.gov (United States)

    Putri, K. Y.; Adawiah, R.

    2018-03-01

    Detection of nanoparticles in solution has been made possible by several means; one of them is laser-induced breakdown detection (LIBD). LIBD is able to distinguish colloids of various sizes and concentrations. This technique has been used in several solubility studies. In this study, the formation of colloids in a mixed system of silver nitrate and sodium chloride was observed by acoustic LIBD. Silver chloride has low solubility limit, therefore LIBD measurement is appropriate. Silver and chloride solutions with equal concentrations, set at below and above the solubility of silver chloride as the expected solid product, were mixed and the resulting colloids were observed. The result of LIBD measurement showed that larger particles were present as more silver and chloride introduced. However, once the concentrations exceeded the solubility limit of silver chloride, the detected particle size seemed to be decreasing, hence suggested the occurrence of coprecipitation process. This phenomenon indicated that the ability of LIBD to detect even small changes in colloid amounts might be a useful tool in study on formation and stability of colloids, i.e. to confirm whether nanoparticles synthesis has been successfully performed and whether the system is stable or not.

  15. Impact of sensor detection limits on protecting water distribution systems from contamination events

    International Nuclear Information System (INIS)

    McKenna, Sean Andrew; Hart, David Blaine; Yarrington, Lane

    2006-01-01

    Real-time water quality sensors are becoming commonplace in water distribution systems. However, field deployable, contaminant-specific sensors are still in the development stage. As development proceeds, the necessary operating parameters of these sensors must be determined to protect consumers from accidental and malevolent contamination events. This objective can be quantified in several different ways including minimization of: the time necessary to detect a contamination event, the population exposed to contaminated water, the extent of the contamination within the network, and others. We examine the ability of a sensor set to meet these objectives as a function of both the detection limit of the sensors and the number of sensors in the network. A moderately sized distribution network is used as an example and different sized sets of randomly placed sensors are considered. For each combination of a certain number of sensors and a detection limit, the mean values of the different objectives across multiple random sensor placements are calculated. The tradeoff between the necessary detection limit in a sensor and the number of sensors is evaluated. Results show that for the example problem examined here, a sensor detection limit of 0.01 of the average source concentration is adequate for maximum protection. Detection of events is dependent on the detection limit of the sensors, but for those events that are detected, the values of the performance measures are not a function of the sensor detection limit. The results of replacing a single sensor in a network with a sensor having a much lower detection limit show that while this replacement can improve results, the majority of the additional events detected had performance measures of relatively low consequence.

  16. Censoring approach to the detection limits in X-ray fluorescence analysis

    International Nuclear Information System (INIS)

    Pajek, M.; Kubala-Kukus, A.

    2004-01-01

    We demonstrate that the effect of detection limits in the X-ray fluorescence analysis (XRF), which limits the determination of very low concentrations of trace elements and results in appearance of the so-called 'nondetects', can be accounted for using the statistical concept of censoring. More precisely, the results of such measurements can be viewed as the left random censored data, which can further be analyzed using the Kaplan-Meier method correcting the data for the presence of nondetects. Using this approach, the results of measured, detection limit censored concentrations can be interpreted in a nonparametric manner including the correction for the nondetects, i.e. the measurements in which the concentrations were found to be below the actual detection limits. Moreover, using the Monte Carlo simulation technique we show that by using the Kaplan-Meier approach the corrected mean concentrations for a population of the samples can be estimated within a few percent uncertainties with respect of the simulated, uncensored data. This practically means that the final uncertainties of estimated mean values are limited in fact by the number of studied samples and not by the correction procedure itself. The discussed random-left censoring approach was applied to analyze the XRF detection-limit-censored concentration measurements of trace elements in biomedical samples

  17. Quantifying Environmental Limiting Factors on Tree Cover Using Geospatial Data

    NARCIS (Netherlands)

    Greenberg, Jonathan; Ferreira Dos Santos, Maria Joao; Dobrowski, Solomon; Vanderbilt, Vern; Ustin, Susan

    2015-01-01

    Environmental limiting factors (ELFs) are the thresholds that determine the maximum or minimum biological response for a given suite of environmental conditions. We asked the following questions: 1) Can we detect ELFs on percent tree cover across the eastern slopes of the Lake Tahoe Basin, NV? 2)

  18. Importance of the lower limit of detection in radiological safety; Importancia del limite inferior de deteccion en seguridad radiologica

    Energy Technology Data Exchange (ETDEWEB)

    Rafael, Terol T; Hermenegildo, Maldonado M [Comision Nacional de Seguridad Nuclear y Salvaguardias (Mexico)

    1991-07-01

    The concept of the Lower Limit of Detection (LLD) it contributes in the solution of some problems related with the radiological safety, such as the realization of the tests of flight of the sealed radioactive sources; the determination of radioisotopes in environmental samples; the estimate of present radionuclides in polluted foods; in general, the detection of small quantities of radioactive materials present in materials of use or consumption by part of the man in his daily life; as the one Lower Limit of Detection is related with topics of statistics, in this work a small review of them is made, it was superficially discussed the mensuration problems related with the establishment of the Lower Limit of Detection.

  19. 40 CFR Table 9 to Subpart Xxxx of... - Minimum Data for Continuous Compliance With the Emission Limits for Tire Production Affected Sources

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 12 2010-07-01 2010-07-01 true Minimum Data for Continuous Compliance With the Emission Limits for Tire Production Affected Sources 9 Table 9 to Subpart XXXX of Part 63... Hazardous Air Pollutants: Rubber Tire Manufacturing Pt. 63, Subpt. XXXX, Table 9 Table 9 to Subpart XXXX of...

  20. Critical review for the determination of the minimum detectable activity (MDA) of alpha-emitter radionuclides in environmental samples

    International Nuclear Information System (INIS)

    Gasco, C.; Anton, M.P.

    1996-12-01

    Different criteria for the calculation of the Minimum Detectable Activity (MDA) of an alpha emitter in environmental levels are reviewed in this report. Practical examples of its application to previously analyzed samples are shown. The authors propose a criteria based on prior calculations that applies to the radiochemical activities performed in the laboratory. The calculation procedure has been discussed with scientist from other laboratories in order to establish a general criteria to calculate the MDA

  1. Detection limits of antimicrobials in ewe milk by delvotest photometric measurements.

    Science.gov (United States)

    Althaus, R L; Torres, A; Montero, A; Balasch, S; Molina, M P

    2003-02-01

    The Delvotest method detection limits per manufacturer's instructions at a fixed reading time of 3 h for 24 antimicrobial agents were determined in ewe milk by photometric measurement. For each drug, eight concentrations were tested on 20 ewe milk samples from individual ewes. Detection limits, determined by means of logistic regression models, were (microg/kg): 3, amoxycillin; 2, ampicillin; 18, cloxacillin; 1, penicillin "G"; 34, cefadroxil; 430, cephalosporin "C"; 40, cephalexin; 20, cefoperazone; 33, Ceftiofur; 18, cefuroxime; 6100, streptomycin; 1200, gentamycin; 2600, neomycin; 830, erythromycin; 100, tylosin; 180, doxycycline; 320, oxytetracycline; 590, tetracycline; 88, sulfadiazine; 44, sulfamethoxazole; 140, sulfametoxypyridazine; 48, sulfaquinoxaline; 12,000, chloramphenicol; and 290, trimethoprim. Whereas the beta-lactam antibiotics, sulphonamides, and tylosin were detected by Delvotest method at levels equal to those of maximum residue limits, its sensitivity needs to be enhanced to detect aminoglycosides, tetracyclines, streptomycin, chloramphenicol, and trimethoprim residues in ewe milk or to develop an integrated residue detection system for ewe milk with different sensitive microorganisms for each group of antiinfectious agents.

  2. Limiter discriminator detection of M-ary FSK signals

    Science.gov (United States)

    Fonseka, John P.

    1990-10-01

    The performance of limiter discriminator detection of M-ary FSK signals is analyzed at arbitrary modulation indices. It is shown that the error rate performance of limiter discriminator detection can be significantly improved by increasing the modulation index above 1/M. The optimum modulation index that minimizes the overall error probability is determined for the cases M = 2, 4 and 8. The analysis is carried out for wideband and bandlimited channels with Gaussian and second-order Butterworth filters. It is shown that the optimum modulation index depends on the signal/noise ratio (SNR), in a wideband channel, and on both SNR and time-bandwidth product in a bandlimited channel. Finally, it is shown that the optimum sampling instance in presence of a nonzero phase IF filter can be approximately determined by using only the worst case symbol pattern.

  3. Realistic limitations of detecting planets around young active stars

    Directory of Open Access Journals (Sweden)

    Pinfield D.

    2013-04-01

    Full Text Available Current planet hunting methods using the radial velocity method are limited to observing middle-aged main-sequence stars where the signatures of stellar activity are much less than on young stars that have just arrived on the main-sequence. In this work we apply our knowledge from the surface imaging of these young stars to place realistic limitations on the possibility of detecting orbiting planets. In general we find that the magnitude of the stellar jitter is directly proportional to the stellar vsini. For G and K dwarfs, we find that it is possible, for models with high stellar activity and low stellar vsini, to be able to detect a 1 MJupiter mass planet within 50 epochs of observations and for the M dwarfs it is possible to detect a habitable zone Earth-like planet in 10s of observational epochs.

  4. Risk control and the minimum significant risk

    International Nuclear Information System (INIS)

    Seiler, F.A.; Alvarez, J.L.

    1996-01-01

    Risk management implies that the risk manager can, by his actions, exercise at least a modicum of control over the risk in question. In the terminology of control theory, a management action is a control signal imposed as feedback on the system to bring about a desired change in the state of the system. In the terminology of risk management, an action is taken to bring a predicted risk to lower values. Even if it is assumed that the management action taken is 100% effective and that the projected risk reduction is infinitely well known, there is a lower limit to the desired effects that can be achieved. It is based on the fact that all risks, such as the incidence of cancer, exhibit a degree of variability due to a number of extraneous factors such as age at exposure, sex, location, and some lifestyle parameters such as smoking or the consumption of alcohol. If the control signal is much smaller than the variability of the risk, the signal is lost in the noise and control is lost. This defines a minimum controllable risk based on the variability of the risk over the population considered. This quantity is the counterpart of the minimum significant risk which is defined by the uncertainties of the risk model. Both the minimum controllable risk and the minimum significant risk are evaluated for radiation carcinogenesis and are shown to be of the same order of magnitude. For a realistic management action, the assumptions of perfectly effective action and perfect model prediction made above have to be dropped, resulting in an effective minimum controllable risk which is determined by both risk limits. Any action below that effective limit is futile, but it is also unethical due to the ethical requirement of doing more good than harm. Finally, some implications of the effective minimum controllable risk on the use of the ALARA principle and on the evaluation of remedial action goals are presented

  5. Maximum/minimum asymmetric rod detection

    International Nuclear Information System (INIS)

    Huston, J.T.

    1990-01-01

    This patent describes a system for determining the relative position of each control rod within a control rod group in a nuclear reactor. The control rod group having at least three control rods therein. It comprises: means for producing a signal representative of a position of each control rod within the control rod group in the nuclear reactor; means for establishing a signal representative of the highest position of a control rod in the control rod group in the nuclear reactor; means for establishing a signal representative of the lowest position of a control rod in the control rod group in the nuclear reactor; means for determining a difference between the signal representative of the position of the highest control rod and the signal representative of the position of the lowest control rod; means for establishing a predetermined limit for the difference between the signal representative of the position of the highest control rod and the signal representative of the position of the lowest control rod; and means for comparing the difference between the signals with the predetermined limit. The comparing means producing an output signal when the difference between the signals exceeds the predetermined limit

  6. Minimum Delay Moving Object Detection

    KAUST Repository

    Lao, Dong

    2017-01-01

    This thesis presents a general framework and method for detection of an object in a video based on apparent motion. The object moves, at some unknown time, differently than the “background” motion, which can be induced from camera motion. The goal

  7. Efficiency calibration and minimum detectable activity concentration of a real-time UAV airborne sensor system with two gamma spectrometers.

    Science.gov (United States)

    Tang, Xiao-Bin; Meng, Jia; Wang, Peng; Cao, Ye; Huang, Xi; Wen, Liang-Sheng; Chen, Da

    2016-04-01

    A small-sized UAV (NH-UAV) airborne system with two gamma spectrometers (LaBr3 detector and HPGe detector) was developed to monitor activity concentration in serious nuclear accidents, such as the Fukushima nuclear accident. The efficiency calibration and determination of minimum detectable activity concentration (MDAC) of the specific system were studied by MC simulations at different flight altitudes, different horizontal distances from the detection position to the source term center and different source term sizes. Both air and ground radiation were considered in the models. The results obtained may provide instructive suggestions for in-situ radioactivity measurements of NH-UAV. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Theoretical detection limit of PIXE analysis using 20 MeV proton beams

    Science.gov (United States)

    Ishii, Keizo; Hitomi, Keitaro

    2018-02-01

    Particle-induced X-ray emission (PIXE) analysis is usually performed using proton beams with energies in the range 2∼3 MeV because at these energies, the detection limit is low. The detection limit of PIXE analysis depends on the X-ray production cross-section, the continuous background of the PIXE spectrum and the experimental parameters such as the beam currents and the solid angle and detector efficiency of X-ray detector. Though the continuous background increases as the projectile energy increases, the cross-section of the X-ray increases as well. Therefore, the detection limit of high energy proton PIXE is not expected to increase significantly. We calculated the cross sections of continuous X-rays produced in several bremsstrahlung processes and estimated the detection limit of a 20 MeV proton PIXE analysis by modelling the Compton tail of the γ-rays produced in the nuclear reactions, and the escape effect on the secondary electron bremsstrahlung. We found that the Compton tail does not affect the detection limit when a thin X-ray detector is used, but the secondary electron bremsstrahlung escape effect does have an impact. We also confirmed that the detection limit of the PIXE analysis, when used with 4 μm polyethylene backing film and an integrated beam current of 1 μC, is 0.4∼2.0 ppm for proton energies in the range 10∼30 MeV and elements with Z = 16-90. This result demonstrates the usefulness of several 10 MeV cyclotrons for performing PIXE analysis. Cyclotrons with these properties are currently installed in positron emission tomography (PET) centers.

  9. Censoring: a new approach for detection limits in total-reflection X-ray fluorescence

    International Nuclear Information System (INIS)

    Pajek, M.; Kubala-Kukus, A.; Braziewicz, J.

    2004-01-01

    It is shown that the detection limits in the total-reflection X-ray fluorescence (TXRF), which restrict quantification of very low concentrations of trace elements in the samples, can be accounted for using the statistical concept of censoring. We demonstrate that the incomplete TXRF measurements containing the so-called 'nondetects', i.e. the non-measured concentrations falling below the detection limits and represented by the estimated detection limit values, can be viewed as the left random-censored data, which can be further analyzed using the Kaplan-Meier (KM) method correcting for nondetects. Within this approach, which uses the Kaplan-Meier product-limit estimator to obtain the cumulative distribution function corrected for the nondetects, the mean value and median of the detection limit censored concentrations can be estimated in a non-parametric way. The Monte Carlo simulations performed show that the Kaplan-Meier approach yields highly accurate estimates for the mean and median concentrations, being within a few percent with respect to the simulated, uncensored data. This means that the uncertainties of KM estimated mean value and median are limited in fact only by the number of studied samples and not by the applied correction procedure for nondetects itself. On the other hand, it is observed that, in case when the concentration of a given element is not measured in all the samples, simple approaches to estimate a mean concentration value from the data yield erroneous, systematically biased results. The discussed random-left censoring approach was applied to analyze the TXRF detection-limit-censored concentration measurements of trace elements in biomedical samples. We emphasize that the Kaplan-Meier approach allows one to estimate the mean concentrations being substantially below the mean level of detection limits. Consequently, this approach gives a new access to lower the effective detection limits for TXRF method, which is of prime interest for

  10. In situ quantification of ultra-low O2 concentrations in oxygen minimum zones

    DEFF Research Database (Denmark)

    Larsen, Morten; Lehner, Philipp; Borisov, Sergey M.

    2016-01-01

    based on the palladium(II)-benzoporphyrin luminophore, immobilized in a perfluorinated matrix with high O2 permeability. The trace sensor has a detection limit of ∼5 nmol L−1 with a dynamic range extending up to ∼2 μmol L−1. The sensor demonstrates a response time ..., and fully reversible response to hydrostatic pressure and temperature. The sensor showed excellent stability for continuously measurements during depth profiling in Oxygen Minimum Zones (OMZ). The novel sensor was deployed in situ using a Trace Oxygen Profiler instrument (TOP) equipped with two additional O...

  11. Optical Coherence Tomography Minimum Intensity as an Objective Measure for the Detection of Hydroxychloroquine Toxicity.

    Science.gov (United States)

    Allahdina, Ali M; Stetson, Paul F; Vitale, Susan; Wong, Wai T; Chew, Emily Y; Ferris, Fredrick L; Sieving, Paul A; Cukras, Catherine

    2018-04-01

    As optical coherence tomography (OCT) minimum intensity (MI) analysis provides a quantitative assessment of changes in the outer nuclear layer (ONL), we evaluated the ability of OCT-MI analysis to detect hydroxychloroquine toxicity. Fifty-seven predominantly female participants (91.2% female; mean age, 55.7 ± 10.4 years; mean time on hydroxychloroquine, 15.0 ± 7.5 years) were enrolled in a case-control study and categorized into affected (i.e., with toxicity, n = 19) and unaffected (n = 38) groups using objective multifocal electroretinographic (mfERG) criteria. Spectral-domain OCT scans of the macula were analyzed and OCT-MI values quantitated for each subfield of the Early Treatment Diabetic Retinopathy Study (ETDRS) grid. A two-sample U-test and a cross-validation approach were used to assess the sensitivity and specificity of toxicity detection according to OCT-MI criteria. The medians of the OCT-MI values in all nine of the ETDRS subfields were significantly elevated in the affected group relative to the unaffected group (P < 0.005 for all comparisons), with the largest difference found for the inner inferior subfield (P < 0.0001). The receiver operating characteristic analysis of median MI values of the inner inferior subfields showed high sensitivity and high specificity in the detection of toxicity with area under the curve = 0.99. Retinal changes secondary to hydroxychloroquine toxicity result in increased OCT reflectivity in the ONL that can be detected and quantitated using OCT-MI analysis. Analysis of OCT-MI values demonstrates high sensitivity and specificity for detecting the presence of hydroxychloroquine toxicity in this cohort and may contribute additionally to current screening practices.

  12. The influence of random and systematic errors on a general definition of minimum detectable amount (MDA) applicable to all radiobioassay measurements

    International Nuclear Information System (INIS)

    Brodsky, A.

    1985-01-01

    An approach to defining minimum detectable amount (MDA) of radioactivity in a sample will be discussed, with the aim of obtaining comments helpful in developing a formulation of MDA that will be broadly applicable to all kinds of radiobioassay measurements, and acceptable to the scientists who make these measurements. Also, the influence of random and systematic errors on the defined MDA are examined

  13. Accuracy, precision, and lower detection limits (a deficit reduction approach)

    International Nuclear Information System (INIS)

    Bishop, C.T.

    1993-01-01

    The evaluation of the accuracy, precision and lower detection limits of the determination of trace radionuclides in environmental samples can become quite sophisticated and time consuming. This in turn could add significant cost to the analyses being performed. In the present method, a open-quotes deficit reduction approachclose quotes has been taken to keep costs low, but at the same time provide defensible data. In order to measure the accuracy of a particular method, reference samples are measured over the time period that the actual samples are being analyzed. Using a Lotus spreadsheet, data are compiled and an average accuracy is computed. If pairs of reference samples are analyzed, then precision can also be evaluated from the duplicate data sets. The standard deviation can be calculated if the reference concentrations of the duplicates are all in the same general range. Laboratory blanks are used to estimate the lower detection limits. The lower detection limit is calculated as 4.65 times the standard deviation of a set of blank determinations made over a given period of time. A Lotus spreadsheet is again used to compile data and LDLs over different periods of time can be compared

  14. Minimum resolvable power contrast model

    Science.gov (United States)

    Qian, Shuai; Wang, Xia; Zhou, Jingjing

    2018-01-01

    Signal-to-noise ratio and MTF are important indexs to evaluate the performance of optical systems. However,whether they are used alone or joint assessment cannot intuitively describe the overall performance of the system. Therefore, an index is proposed to reflect the comprehensive system performance-Minimum Resolvable Radiation Performance Contrast (MRP) model. MRP is an evaluation model without human eyes. It starts from the radiance of the target and the background, transforms the target and background into the equivalent strips,and considers attenuation of the atmosphere, the optical imaging system, and the detector. Combining with the signal-to-noise ratio and the MTF, the Minimum Resolvable Radiation Performance Contrast is obtained. Finally the detection probability model of MRP is given.

  15. Electronic Nose Testing Procedure for the Definition of Minimum Performance Requirements for Environmental Odor Monitoring

    Directory of Open Access Journals (Sweden)

    Lidia Eusebio

    2016-09-01

    Full Text Available Despite initial enthusiasm towards electronic noses and their possible application in different fields, and quite a lot of promising results, several criticalities emerge from most published research studies, and, as a matter of fact, the diffusion of electronic noses in real-life applications is still very limited. In general, a first step towards large-scale-diffusion of an analysis method, is standardization. The aim of this paper is describing the experimental procedure adopted in order to evaluate electronic nose performances, with the final purpose of establishing minimum performance requirements, which is considered to be a first crucial step towards standardization of the specific case of electronic nose application for environmental odor monitoring at receptors. Based on the experimental results of the performance testing of a commercialized electronic nose type with respect to three criteria (i.e., response invariability to variable atmospheric conditions, instrumental detection limit, and odor classification accuracy, it was possible to hypothesize a logic that could be adopted for the definition of minimum performance requirements, according to the idea that these are technologically achievable.

  16. Prediction of the limit of detection of an optical resonant reflection biosensor.

    Science.gov (United States)

    Hong, Jongcheol; Kim, Kyung-Hyun; Shin, Jae-Heon; Huh, Chul; Sung, Gun Yong

    2007-07-09

    A prediction of the limit of detection of an optical resonant reflection biosensor is presented. An optical resonant reflection biosensor using a guided-mode resonance filter is one of the most promising label-free optical immunosensors due to a sharp reflectance peak and a high sensitivity to the changes of optical path length. We have simulated this type of biosensor using rigorous coupled wave theory to calculate the limit of detection of the thickness of the target protein layer. Theoretically, our biosensor has an estimated ability to detect thickness change approximately the size of typical antigen proteins. We have also investigated the effects of the absorption and divergence of the incident light on the detection ability of the biosensor.

  17. The effects of oxygen on process rates and gene expression of anammox and denitrification in the Eastern South Pacific oxygen minimum zone

    DEFF Research Database (Denmark)

    Dalsgaard, Tage; Stewart, Frank; De Brabandere, Loreto

    Oxygen concentrations were consistently below our detection limit of 90 nM for a distance of > 2000 km in the oxygen minimum zone (OMZ) along the coasts of Chile and Peru. In most cases, anammox and denitrification were only detected when in situ oxygen concentrations were below detection...... differently to oxygen. When normalized to a housekeeping gene (rpoB), the expression of 4 out of 9 N-cycle-genes changed with increasing oxygen concentration: The expression of ammonium monooxygenase (amoC) was stimulated, whereas expression of nitrite reductase (nirS), nitric oxide reductase (nor...

  18. Reliability, standard error, and minimum detectable change of clinical pressure pain threshold testing in people with and without acute neck pain.

    Science.gov (United States)

    Walton, David M; Macdermid, Joy C; Nielson, Warren; Teasell, Robert W; Chiasson, Marco; Brown, Lauren

    2011-09-01

    Clinical measurement. To evaluate the intrarater, interrater, and test-retest reliability of an accessible digital algometer, and to determine the minimum detectable change in normal healthy individuals and a clinical population with neck pain. Pressure pain threshold testing may be a valuable assessment and prognostic indicator for people with neck pain. To date, most of this research has been completed using algometers that are too resource intensive for routine clinical use. Novice raters (physiotherapy students or clinical physiotherapists) were trained to perform algometry testing over 2 clinically relevant sites: the angle of the upper trapezius and the belly of the tibialis anterior. A convenience sample of normal healthy individuals and a clinical sample of people with neck pain were tested by 2 different raters (all participants) and on 2 different days (healthy participants only). Intraclass correlation coefficient (ICC), standard error of measurement, and minimum detectable change were calculated. A total of 60 healthy volunteers and 40 people with neck pain were recruited. Intrarater reliability was almost perfect (ICC = 0.94-0.97), interrater reliability was substantial to near perfect (ICC = 0.79-0.90), and test-retest reliability was substantial (ICC = 0.76-0.79). Smaller change was detectable in the trapezius compared to the tibialis anterior. This study provides evidence that novice raters can perform digital algometry with adequate reliability for research and clinical use in people with and without neck pain.

  19. Leak detection : Principles and practice

    International Nuclear Information System (INIS)

    Rama Rao, V.V.K.

    1981-01-01

    Principles of leak detection are explained and various aspects of leak detection techniques and leak detectors are reviewed. The review covers: units for leaks and leak tightness, classification of leaks, timing of leak testing, designing for ease of leak testing of any job, methods of leak detection, their ranges of application and limitations, leak detectors, response time of leak test, minimum detectable concentration of search gas during leak tests, and validity of leak tests. Helium mass spectrometer type leak detector and technique are described in detail. Recent improvements in leak detectors and techniques, particularly mass spectrometer leak detectors using gases other than helium (e.g. hydrogen, argon) are also covered in the review. (M.G.B.)

  20. Minimum Benefits for HIV/AIDS in South African Medical Schemes ...

    African Journals Online (AJOL)

    ... to the Minister of Health in respect of the extent of prescribed minimum benefits for HIV/AIDS. Medical schemes are required to provide the PMBs to their members without limits or co-payments. Keywords: Medical schemes; HIV; AIDS; benefits; prescribed minimum benefits. South African Actuarial Journal: 2003 3: 77-112 ...

  1. The Effect of Minimum Wage Rates on High School Completion

    Science.gov (United States)

    Warren, John Robert; Hamrock, Caitlin

    2010-01-01

    Does increasing the minimum wage reduce the high school completion rate? Previous research has suffered from (1. narrow time horizons, (2. potentially inadequate measures of states' high school completion rates, and (3. potentially inadequate measures of minimum wage rates. Overcoming each of these limitations, we analyze the impact of changes in…

  2. Improvement in Limit of Detection of Enzymatic Biogas Sensor Utilizing Chromatography Paper for Breath Analysis.

    Science.gov (United States)

    Motooka, Masanobu; Uno, Shigeyasu

    2018-02-02

    Breath analysis is considered to be an effective method for point-of-care diagnosis due to its noninvasiveness, quickness and simplicity. Gas sensors for breath analysis require detection of low-concentration substances. In this paper, we propose that reduction of the background current improves the limit of detection of enzymatic biogas sensors utilizing chromatography paper. After clarifying the cause of the background current, we reduced the background current by improving the fabrication process of the sensors utilizing paper. Finally, we evaluated the limit of detection of the sensor with the sample vapor of ethanol gas. The experiment showed about a 50% reduction of the limit of detection compared to previously-reported sensor. This result presents the possibility of the sensor being applied in diagnosis, such as for diabetes, by further lowering the limit of detection.

  3. Determining the lower limit of detection for personnel dosimetry systems

    International Nuclear Information System (INIS)

    Roberson, P.L.; Carlson, R.D.

    1992-01-01

    A simple method for determining the lower limit of detection (LLD) for personnel dosimetry systems is described. The method relies on the definition of a critical level and a detection level. The critical level is the signal level above which a result has a small probability of being due to a fluctuation of the background. All results below the critical level should not be reported as an indication of a positive result. The detection level is the net signal level (i.e., dose received) above which there is a high confidence that a true reading will be detected and reported as a qualitatively positive result. The detection level may be identified as the LLD. A simple formula is derived to allow the calculation of the LLD under various conditions. This type of formula is being used by the Department of Energy Laboratory Accreditation Program (DOELAP) for personnel dosimetry. Participants in either the National Voluntary Laboratory Accreditation Program (NVLAP) for personnel dosimetry or DOELAP can use performance test results along with a measurement of background levels to estimate the LLDs for their dosimetry system. As long as they maintain their dosimetry system such that the LLDs are less than half the lower limit of the NVLAP or DOELAP test exposure ranges, dosimetry laboratories can avoid testing failures due to poor performance at very low exposures

  4. How low can the detection limit go with VPD-TXRF

    International Nuclear Information System (INIS)

    Wang, J.; Balazs, M.; Pianetta, P.; Baur, K.; Brennan, S.; Boone, T.; Rosamilia, J.

    2000-01-01

    The detection limit for synchrotron radiation total reflection x-ray fluorescence (TXRF) that can routinely be achieved for transition metals is about 8E7 atoms/cm 2 for a standard 1000 second counting time. This high sensitivity can be further improved by using a pre-concentration process such as vapor phase decomposition (VPD). The sensitivity enhancement of VPD-TXRF over TXRF is usually estimated from the ratio of the total wafer surface area to the instrumental sampling area on the wafer. For example, a 200 mm wafer with a 5 mm edge exclusion has a total surface area of 283.5 cm 2 . Assuming a sampling area of 0.126 cm 2 for the TXRF instrument at the Stanford Synchrotron Radiation Laboratory (SSRL) the gain in sensitivity for the VPD-TXRF technique will be 1 : 2250. This means, theoretically, that the TXRF detection limit of 8E7 atoms/cm 2 could be further reduced to 3.6 E4 atoms/cm 2 by applying this technique. During the VPD process, the contaminants on the wafer surface will be collected into a single droplet and dried on the wafer surface for TXRF analysis. However, impurities in the UPW (ultra pure water), chemicals or from handling cannot be ignored. Our investigation of wafers subjected, to different cleaning processes has revealed that background signals on the dry spot could arise from the VPD process itself. Therefore, the baseline determined by the purity of the UPW and starting chemicals limits the detection limits of VPD-SR-TXRF. (author)

  5. Visualizing the Limits of Low Vision in Detecting Natural Image Features

    NARCIS (Netherlands)

    Hogervorst, M.A.; Damme, W.J.M. van

    2008-01-01

    Purpose. The purpose of our study was to develop a tool to visualize the limitations posed by visual impairments in detecting small and low-contrast elements in natural images. This visualization tool incorporates existing models of several aspects of visual perception, such as the band-limited

  6. Quality control of radiation counting systems and measurement of minimum detectable activity

    International Nuclear Information System (INIS)

    Song, Byoung Chul; Han, Sung Sim; Kim, Young Bok; Jee, Kwang Yong; Sohn, Se Chul

    2004-01-01

    Various radiation counters have been using to determine radioactivity of radwastes for disposal. A radiation counting system was set up using a radiation detector chosen in this study and its stability was investigated through the periodic determination of background and counting efficiencies in accordance with a quality control program to increase the confidence level. The average background level for the γ-spectrometer was 1.59 cps and the average counting level for the standard sample was 45248 dps within 20 confidence levels. The average alpha background level for the low background α/β counting system was 0.31 cpm and the efficiency for alpha counting was 34.38 %. The average beta background level for the α/β counting system was 1.30 cpm and the efficiency for beta counting was 46.5%. The background level in the region of 3H and 14C for the liquid scintillation counting system was 2.52 and 3.31 cpm and the efficiency for alpha counting was 58.5 and 95.6%, respectively. The minimum detectable activity for the γ-spectrometer was found to be 3.2 Bq/mL and 3.8 Bq/mL for the liquid scintillation counter, and 20.5 and 23.0 Bq/mL, respectively for the α and β counting system

  7. Accuracy and detection limits for bioassay measurements in radiation protection. Statistical considerations

    International Nuclear Information System (INIS)

    Brodsky, A.

    1986-04-01

    This report provides statistical concepts and formulas for defining minimum detectable amount (MDA), bias and precision of sample analytical measurements of radioactivity for radiobioassay purposes. The defined statistical quantities and accuracy criteria were developed for use in standard performance criteria for radiobioassay, but are also useful in intralaboratory quality assurance programs. This report also includes a literature review and analysis of accuracy needs and accuracy recommendations of national and international scientific organizations for radiation or radioactivity measurements used for radiation protection purposes. Computer programs are also included for calculating the probabilities of passing or failing multiple analytical tests for different acceptable ranges of bias and precision

  8. Calculation of risk-based detection limits for radionuclides in the liquid effluents from Korean nuclear power plants

    International Nuclear Information System (INIS)

    Cheong, Jae Hak

    2017-01-01

    In order to review if present detection limits of radionuclides in liquid effluent from nuclear power plants are effective enough to warrant compliance with regulatory discharge limits, a risk-based approach is developed to derive a new detection limit for each radionuclide based on radiological criteria. Equations and adjustment factors are also proposed to discriminate the validity of the detection limits for multiple radionuclides in the liquid effluent with or without consideration of the nuclide composition. From case studies to three nuclear power plants in Korea with actual operation data from 2006 to 2015, the present detection limits have turned out to be effective for Hanul Unit 1 but may not be sensitive enough for Kori Unit 1 (8 out of 14 radionuclides) and Wolsong Unit 1 (9 out of 42 radionuclides). However, it is shown that the present detection limits for the latter two nuclear power plants can be justified, if credit is given to the radionuclide composition. Otherwise, consideration should be given to adjustment of the present detection limits. The risk-based approach of this study can be used to determine the validity of established detection limits of a specific nuclear power plant. (author)

  9. Gold nanoparticle-based low limit of detection Love wave biosensor for carcinoembryonic antigens.

    Science.gov (United States)

    Li, Shuangming; Wan, Ying; Su, Yan; Fan, Chunhai; Bhethanabotla, Venkat R

    2017-09-15

    In this work, a Love wave biosensing platform is described for detecting cancer-related biomarker carcinoembryonic antigen (CEA). An ST 90°-X quartz Love wave device with a layer of SiO 2 waveguide was combined with gold nanoparticles (Au NPs) to amplify the mass loading effect of the acoustic wave sensor to achieve a limit of detection of 37pg/mL. The strategy involves modifying the Au NPs with anti-CEA antibody conjugates to form nanoprobes in a sandwich immunoassay. The unamplified detection limit of the Love wave biosensor is 9.4ng/mL. This 2-3 order of magnitude reduction in the limit of detection brings the SAW platform into the range useful for clinical diagnosis. Measurement electronics and microfluidics are easily constructed for acoustic wave biosensors, such as the Love wave device described here, allowing for robust platforms for point of care applications for cancer biomarkers in general. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. On the relationship of minimum detectable contrast to dose and lesion size in abdominal CT

    International Nuclear Information System (INIS)

    Zhou, Yifang; Scott, Alexander II; Allahverdian, Janet; Lee, Christina; Kightlinger, Blake; Azizyan, Avetis; Miller, Joseph

    2015-01-01

    CT dose optimization is typically guided by pixel noise or contrast-to-noise ratio that does not delineate low contrast details adequately. We utilized the statistically defined low contrast detectability to study its relationship to dose and lesion size in abdominal CT. A realistically shaped medium sized abdomen phantom was customized to contain a cylindrical void of 4 cm diameter. The void was filled with a low contrast (1% and 2%) insert containing six groups of cylindrical targets ranging from 1.2 mm to 7 mm in size. Helical CT scans were performed using a Siemens 64-slice mCT and a GE Discovery 750 HD at various doses. After the subtractions between adjacent slices, the uniform sections of the filtered backprojection reconstructed images were partitioned to matrices of square elements matching the sizes of the targets. It was verified that the mean values from all the elements in each matrix follow a Gaussian distribution. The minimum detectable contrast (MDC), quantified by the mean signal to background difference equal to the distribution’s standard deviation multiplied by 3.29, corresponding to 95% confidence level, was found to be related to the phantom specific dose and the element size by a power law (R 2   >  0.990). Independent readings on the 5 mm and 7 mm targets were compared to the measured contrast to the MDC ratios. The results showed that 93% of the cases were detectable when the measured contrast exceeds the MDC. The correlation of the MDC to the pixel noise and target size was also identified and the relationship was found to be the same for the scanners in the study. To quantify the impact of iterative reconstructions to the low contrast detectability, the noise structure was studied in a similar manner at different doses and with different ASIR blending fractions. The relationship of the dose to the blending fraction and low contrast detectability is presented. (paper)

  11. On the relationship of minimum detectable contrast to dose and lesion size in abdominal CT

    Science.gov (United States)

    Zhou, Yifang; Scott, Alexander, II; Allahverdian, Janet; Lee, Christina; Kightlinger, Blake; Azizyan, Avetis; Miller, Joseph

    2015-10-01

    CT dose optimization is typically guided by pixel noise or contrast-to-noise ratio that does not delineate low contrast details adequately. We utilized the statistically defined low contrast detectability to study its relationship to dose and lesion size in abdominal CT. A realistically shaped medium sized abdomen phantom was customized to contain a cylindrical void of 4 cm diameter. The void was filled with a low contrast (1% and 2%) insert containing six groups of cylindrical targets ranging from 1.2 mm to 7 mm in size. Helical CT scans were performed using a Siemens 64-slice mCT and a GE Discovery 750 HD at various doses. After the subtractions between adjacent slices, the uniform sections of the filtered backprojection reconstructed images were partitioned to matrices of square elements matching the sizes of the targets. It was verified that the mean values from all the elements in each matrix follow a Gaussian distribution. The minimum detectable contrast (MDC), quantified by the mean signal to background difference equal to the distribution’s standard deviation multiplied by 3.29, corresponding to 95% confidence level, was found to be related to the phantom specific dose and the element size by a power law (R^2  >  0.990). Independent readings on the 5 mm and 7 mm targets were compared to the measured contrast to the MDC ratios. The results showed that 93% of the cases were detectable when the measured contrast exceeds the MDC. The correlation of the MDC to the pixel noise and target size was also identified and the relationship was found to be the same for the scanners in the study. To quantify the impact of iterative reconstructions to the low contrast detectability, the noise structure was studied in a similar manner at different doses and with different ASIR blending fractions. The relationship of the dose to the blending fraction and low contrast detectability is presented.

  12. 49 CFR 387.303 - Security for the protection of the public: Minimum limits.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Security for the protection of the public: Minimum... Insurance for Motor Carriers and Property Brokers § 387.303 Security for the protection of the public... convenience of the user, the revised text is set forth as follows: § 387.303 Security for the protection of...

  13. Detection limit of 238U by gamma spectrometry

    International Nuclear Information System (INIS)

    Tartaglione, A.; Blostein, J.; Mayer, R

    2004-01-01

    The detection limit of 238 U was determined by gamma spectra measurements of a depleted uranium sample using four NaI(Tl) scintillators in a compact arrangement.The sample was shielded with 5 and 10 cm of lead.Two different methods for data processing were used and compared.It was established that an appropriate array of 40 detectors could establish the presence of 220 g of this material in only 5 minutes [es

  14. The impact of the minimum wage on health.

    Science.gov (United States)

    Andreyeva, Elena; Ukert, Benjamin

    2018-03-07

    This study evaluates the effect of minimum wage on risky health behaviors, healthcare access, and self-reported health. We use data from the 1993-2015 Behavioral Risk Factor Surveillance System, and employ a difference-in-differences strategy that utilizes time variation in new minimum wage laws across U.S. states. Results suggest that the minimum wage increases the probability of being obese and decreases daily fruit and vegetable intake, but also decreases days with functional limitations while having no impact on healthcare access. Subsample analyses reveal that the increase in weight and decrease in fruit and vegetable intake are driven by the older population, married, and whites. The improvement in self-reported health is especially strong among non-whites, females, and married.

  15. Practical low dose limits for passive personal dosemeters and the implications for uncertainties close to the limit of detection

    International Nuclear Information System (INIS)

    Gilvin, P. J.; Perks, C. A.

    2011-01-01

    Recent years have seen the increasing use of passive dosemeters that have high sensitivities and, in laboratory conditions, detection limits of <10 μSv. However, in real operational use the detection limits will be markedly higher, because a large fraction of the accrued dose will be due to natural background, and this must be subtracted in order to obtain the desired occupational dose. No matter how well known the natural background is, the measurement uncertainty on doses of a few tens of microsieverts will be large. Individual monitoring services need to recognise this and manage the expectations of their clients by providing sufficient information. (authors)

  16. The minimum mass of detectable planets in protoplanetary discs and the derivation of planetary masses from high-resolution observations.

    Science.gov (United States)

    Rosotti, Giovanni P; Juhasz, Attila; Booth, Richard A; Clarke, Cathie J

    2016-07-01

    We investigate the minimum planet mass that produces observable signatures in infrared scattered light and submillimetre (submm) continuum images and demonstrate how these images can be used to measure planet masses to within a factor of about 2. To this end, we perform multi-fluid gas and dust simulations of discs containing low-mass planets, generating simulated observations at 1.65, 10 and 850 μm. We show that the minimum planet mass that produces a detectable signature is ∼15 M ⊕ : this value is strongly dependent on disc temperature and changes slightly with wavelength (favouring the submm). We also confirm previous results that there is a minimum planet mass of ∼20 M ⊕ that produces a pressure maximum in the disc: only planets above this threshold mass generate a dust trap that can eventually create a hole in the submm dust. Below this mass, planets produce annular enhancements in dust outwards of the planet and a reduction in the vicinity of the planet. These features are in steady state and can be understood in terms of variations in the dust radial velocity, imposed by the perturbed gas pressure radial profile, analogous to a traffic jam. We also show how planet masses can be derived from structure in scattered light and submm images. We emphasize that simulations with dust need to be run over thousands of planetary orbits so as to allow the gas profile to achieve a steady state and caution against the estimation of planet masses using gas-only simulations.

  17. Determination and Interpretation of Characteristic Limits for Radioactivity Measurements: Decision Threshhold, Detection Limit and Limits of the Confidence Interval

    International Nuclear Information System (INIS)

    2017-01-01

    Since 2004, the environment programme of the IAEA has included activities aimed at developing a set of procedures for analytical measurements of radionuclides in food and the environment. Reliable, comparable and fit for purpose results are essential for any analytical measurement. Guidelines and national and international standards for laboratory practices to fulfil quality assurance requirements are extremely important when performing such measurements. The guidelines and standards should be comprehensive, clearly formulated and readily available to both the analyst and the customer. ISO 11929:2010 is the international standard on the determination of the characteristic limits (decision threshold, detection limit and limits of the confidence interval) for measuring ionizing radiation. For nuclear analytical laboratories involved in the measurement of radioactivity in food and the environment, robust determination of the characteristic limits of radioanalytical techniques is essential with regard to national and international regulations on permitted levels of radioactivity. However, characteristic limits defined in ISO 11929:2010 are complex, and the correct application of the standard in laboratories requires a full understanding of various concepts. This publication provides additional information to Member States in the understanding of the terminology, definitions and concepts in ISO 11929:2010, thus facilitating its implementation in Member State laboratories.

  18. Derivatizations for improved detection of alcohols by gas chromatography and photoionization detection (GC-PID)

    International Nuclear Information System (INIS)

    Krull, I.S.; Swartz, M.; Driscoll, J.N.

    1984-01-01

    Pentafluorophenyldimethylsilyl chloride (flophemesyl chloride, Fl) is a well known derivatization reagent for improved electron capture detection (ECD) in gas chromatography (GC)(GC-ECD), but it has never been utilized for improved detectability and sensitivity in GC-photoionization detection (GC-PID). A wide variety of flophemesyl alcohol derivatives have been used in order to show a new approach for realizing greatly reduced minimum detection limits (MDL) of virtually all alcohol derivatives in GC-PID analysis. This particular derivatization approach is inexpensive and easy to apply, leading to quantitative or near 100% conversion of the starting alcohols to the expected flophemesyl ethers (silyl ethers). Detection limits can be lowered by 2-3 orders of magnitude for such derivatives when compared with the starting alcohols, along with calibration plots that are linear over 5-7 orders of magnitude. Specific GC conditions have been developed for many flophemesyl derivatives, in all cases using packed columns. Both ECD and PID relative response factors (RRFs) and normalized RRFs have been determined, and such ratios can now be used for improved analytic identification from complex sample matrices, where appropriate. 28 references, 2 figures, 5 tables

  19. Calculating exclusion limits for weakly interacting massive particle direct detection experiments without background subtraction

    International Nuclear Information System (INIS)

    Green, Anne M.

    2002-01-01

    Competitive limits on the weakly interacting massive particle (WIMP) spin-independent scattering cross section are currently being produced by 76 Ge detectors originally designed to search for neutrinoless double beta decay, such as the Heidelberg-Moscow and IGEX experiments. In the absence of background subtraction, limits on the WIMP interaction cross section are set by calculating the upper confidence limit on the theoretical event rate, given the observed event rate. The standard analysis technique involves calculating the 90% upper confidence limit on the number of events in each bin, and excluding any set of parameters (WIMP mass and cross section) which produces a theoretical event rate for any bin which exceeds the 90% upper confidence limit on the event rate for that bin. We show that, if there is more than one energy bin, this produces exclusion limits that are actually at a lower degree of confidence than 90%, and are hence erroneously tight. We formulate criteria which produce true 90% confidence exclusion limits in these circumstances, including calculating the individual bin confidence limit for which the overall probability that no bins exceed this confidence limit is 90% and calculating the 90% minimum confidence limit on the number of bins which exceed their individual bin 90% confidence limits. We then compare the limits on the WIMP cross section produced by these criteria with those found using the standard technique, using data from the Heidelberg-Moscow and IGEX experiments

  20. Weighted Polynomial Approximation for Automated Detection of Inspiratory Flow Limitation

    Directory of Open Access Journals (Sweden)

    Sheng-Cheng Huang

    2017-01-01

    Full Text Available Inspiratory flow limitation (IFL is a critical symptom of sleep breathing disorders. A characteristic flattened flow-time curve indicates the presence of highest resistance flow limitation. This study involved investigating a real-time algorithm for detecting IFL during sleep. Three categories of inspiratory flow shape were collected from previous studies for use as a development set. Of these, 16 cases were labeled as non-IFL and 78 as IFL which were further categorized into minor level (20 cases and severe level (58 cases of obstruction. In this study, algorithms using polynomial functions were proposed for extracting the features of IFL. Methods using first- to third-order polynomial approximations were applied to calculate the fitting curve to obtain the mean absolute error. The proposed algorithm is described by the weighted third-order (w.3rd-order polynomial function. For validation, a total of 1,093 inspiratory breaths were acquired as a test set. The accuracy levels of the classifications produced by the presented feature detection methods were analyzed, and the performance levels were compared using a misclassification cobweb. According to the results, the algorithm using the w.3rd-order polynomial approximation achieved an accuracy of 94.14% for IFL classification. We concluded that this algorithm achieved effective automatic IFL detection during sleep.

  1. Efficiency calibration and minimum detectable activity concentration of a real-time UAV airborne sensor system with two gamma spectrometers

    International Nuclear Information System (INIS)

    Tang, Xiao-Bin; Meng, Jia; Wang, Peng; Cao, Ye; Huang, Xi; Wen, Liang-Sheng; Chen, Da

    2016-01-01

    A small-sized UAV (NH-UAV) airborne system with two gamma spectrometers (LaBr_3 detector and HPGe detector) was developed to monitor activity concentration in serious nuclear accidents, such as the Fukushima nuclear accident. The efficiency calibration and determination of minimum detectable activity concentration (MDAC) of the specific system were studied by MC simulations at different flight altitudes, different horizontal distances from the detection position to the source term center and different source term sizes. Both air and ground radiation were considered in the models. The results obtained may provide instructive suggestions for in-situ radioactivity measurements of NH-UAV. - Highlights: • A small-sized UAV airborne sensor system was developed. • Three radioactive models were chosen to simulate the Fukushima accident. • Both the air and ground radiation were considered in the models. • The efficiency calculations and MDAC values were given. • The sensor system is able to monitor in serious nuclear accidents.

  2. Measurement limits to 134Cs concentration in soil

    International Nuclear Information System (INIS)

    Ahn, J.K.; Kim, J.S.; Lee, H.M.; Kim, H.; Kim, T.H.; Park, J.N.; Kang, Y.S.; Lee, H.S.; Kim, S.J.; Park, J.Y.; Ryu, S.Y.; Kim, H.-Ch.; Kang, W.G.; Kim, S.K.

    2011-01-01

    We investigate the caesium concentrations in soils in mountain areas near Gori nuclear power plant in Korea, focusing on the measurement limits to the 134 Cs. In order to lower the minimum detectable amount (MDA) of activity for the 134 Cs, we have used the ammonium molybdophosphate (AMP) precipitation method to get rid of the 40 K existing in natural radioactivity, which reduces the MDA activity about 10 times smaller than those without the AMP precipitation method. The MDA results for the 134 Cs were found to be in the range between 0.015 and 0.044 Bq/kg-dry weight. In order to diminish the background, we also have measured a part of the soil samples in Yangyang, a small town in the east coast of Korea. However, it turns out that in order to detect the 134 Cs in the samples the MDA should be reduced to the level of mBq/kg-dry weight. - Highlights: → We study the caesium concentrations in soils in mountain areas near Gori NPT in Korea. → We use the AMP precipitation method to lower the minimum detectable amount (MDA) of activity for the 134 Cs. → The results of the MDA for the 134 Cs turn out to be in the range between 0.015 and 0.044. → In order to detect the 134 Cs in the samples, the MDA should be reduced to the level of mBq/kg-dry weight.

  3. Including Below Detection Limit Samples in Post Decommissioning Soil Sample Analyses

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jung Hwan; Yim, Man Sung [KAIST, Daejeon (Korea, Republic of)

    2016-05-15

    To meet the required standards the site owner has to show that the soil at the facility has been sufficiently cleaned up. To do this one must know the contamination of the soil at the site prior to clean up. This involves sampling that soil to identify the degree of contamination. However there is a technical difficulty in determining how much decontamination should be done. The problem arises when measured samples are below the detection limit. Regulatory guidelines for site reuse after decommissioning are commonly challenged because the majority of the activity in the soil at or below the limit of detection. Using additional statistical analyses of contaminated soil after decommissioning is expected to have the following advantages: a better and more reliable probabilistic exposure assessment, better economics (lower project costs) and improved communication with the public. This research will develop an approach that defines an acceptable method for demonstrating compliance of decommissioned NPP sites and validates that compliance. Soil samples from NPP often contain censored data. Conventional methods for dealing with censored data sets are statistically biased and limited in their usefulness.

  4. Discriminating between antihydrogen and mirror-trapped antiprotons in a minimum-B trap

    CERN Document Server

    Amole, C; Ashkezari, M D; Baquero-Ruiz, M; Bertsche, W; Butler, E; Cesar, C L; Chapman, S; Charlton, M; Deller, A; Eriksson, S; Fajans, J; Friesen, T; Fujiwara, M C; Gill, D R; Gutierrez, A; Hangst, J S; Hardy, W N; Hayden, M E; Humphries, A J; Hydomako, R; Kurchaninov, L; Jonsell, S; Madsen, N; Menary, S; Nolan, P; Olchanski, K; Olin, A; Povilus, A; Pusa, P; Robicheaux, F; Sarid, E; Silveira, D M; So, C; Storey, J W; Thompson, R I; van der Werf, D P; Wurtele, J S

    2012-01-01

    Recently, antihydrogen atoms were trapped at CERN in a magnetic minimum (minimum-B) trap formed by superconducting octupole and mirror magnet coils. The trapped antiatoms were detected by rapidly turning off these magnets, thereby eliminating the magnetic minimum and releasing any antiatoms contained in the trap. Once released, these antiatoms quickly hit the trap wall, whereupon the positrons and antiprotons in the antiatoms annihilated. The antiproton annihilations produce easily detected signals; we used these signals to prove that we trapped antihydrogen. However, our technique could be confounded by mirror-trapped antiprotons, which would produce seemingly-identical annihilation signals upon hitting the trap wall. In this paper, we discuss possible sources of mirror-trapped antiprotons and show that antihydrogen and antiprotons can be readily distinguished, often with the aid of applied electric fields, by analyzing the annihilation locations and times. We further discuss the general properties of antipr...

  5. Detection limit for rate fluctuations in inhomogeneous Poisson processes

    Science.gov (United States)

    Shintani, Toshiaki; Shinomoto, Shigeru

    2012-04-01

    Estimations of an underlying rate from data points are inevitably disturbed by the irregular occurrence of events. Proper estimation methods are designed to avoid overfitting by discounting the irregular occurrence of data, and to determine a constant rate from irregular data derived from a constant probability distribution. However, it can occur that rapid or small fluctuations in the underlying density are undetectable when the data are sparse. For an estimation method, the maximum degree of undetectable rate fluctuations is uniquely determined as a phase transition, when considering an infinitely long series of events drawn from a fluctuating density. In this study, we analytically examine an optimized histogram and a Bayesian rate estimator with respect to their detectability of rate fluctuation, and determine whether their detectable-undetectable phase transition points are given by an identical formula defining a degree of fluctuation in an underlying rate. In addition, we numerically examine the variational Bayes hidden Markov model in its detectability of rate fluctuation, and determine whether the numerically obtained transition point is comparable to those of the other two methods. Such consistency among these three principled methods suggests the presence of a theoretical limit for detecting rate fluctuations.

  6. Detection limit for rate fluctuations in inhomogeneous Poisson processes.

    Science.gov (United States)

    Shintani, Toshiaki; Shinomoto, Shigeru

    2012-04-01

    Estimations of an underlying rate from data points are inevitably disturbed by the irregular occurrence of events. Proper estimation methods are designed to avoid overfitting by discounting the irregular occurrence of data, and to determine a constant rate from irregular data derived from a constant probability distribution. However, it can occur that rapid or small fluctuations in the underlying density are undetectable when the data are sparse. For an estimation method, the maximum degree of undetectable rate fluctuations is uniquely determined as a phase transition, when considering an infinitely long series of events drawn from a fluctuating density. In this study, we analytically examine an optimized histogram and a Bayesian rate estimator with respect to their detectability of rate fluctuation, and determine whether their detectable-undetectable phase transition points are given by an identical formula defining a degree of fluctuation in an underlying rate. In addition, we numerically examine the variational Bayes hidden Markov model in its detectability of rate fluctuation, and determine whether the numerically obtained transition point is comparable to those of the other two methods. Such consistency among these three principled methods suggests the presence of a theoretical limit for detecting rate fluctuations.

  7. Improved detection limits for phthalates by selective solid-phase micro-extraction

    KAUST Repository

    Zia, Asif I.; Afsarimanesh, Nasrin; Xie, Li; Nag, Anindya; Al-Bahadly, I. H.; Yu, P. L.; Kosel, Jü rgen

    2016-01-01

    Presented research reports on an improved method and enhanced limits of detection for phthalates; a hazardous additive used in the production of plastics by solid-phase micro-extraction (SPME) polymer in comparison to molecularly imprinted solid

  8. Fabrication of Stretchable Copper Coated Carbon Nanotube Conductor for Non-Enzymatic Glucose Detection Electrode with Low Detection Limit and Selectivity

    Directory of Open Access Journals (Sweden)

    Dawei Jiang

    2018-03-01

    Full Text Available The increasing demand for wearable glucose sensing has stimulated growing interest in stretchable electrodes. The development of the electrode materials having large stretchability, low detection limit, and good selectivity is the key component for constructing high performance wearable glucose sensors. In this work, we presented fabrication of stretchable conductor based on the copper coated carbon nanotube sheath-core fiber, and its application as non-enzymatic electrode for glucose detection with high stretchability, low detection limit, and selectivity. The sheath-core fiber was fabricated by coating copper coated carbon nanotube on a pre-stretched rubber fiber core followed by release of pre-stretch, which had a hierarchically buckled structure. It showed a small resistance change as low as 27% as strain increasing from 0% to 500% strain, and a low resistance of 0.4 Ω·cm−1 at strain of 500%. This electrode showed linear glucose concentration detection in the range between 0.05 mM and 5 mM and good selectivity against sucrose, lactic acid, uric acid, acrylic acid in phosphate buffer saline solution, and showed stable signal in high salt concentration. The limit of detection (LOD was 0.05 mM, for the range of 0.05–5 mM, the sensitivity is 46 mA·M−1. This electrode can withstand large strain of up to 60% with negligible influence on its performance.

  9. The detection limits of antimicrobial agents in cow's milk by a simple Yoghurt Culture Test.

    Science.gov (United States)

    Mohsenzadeh, M; Bahrainipour, A

    2008-09-15

    The aim of this study was to study performance of Yoghurt Culture Test (YCT) in the detection of antimicrobial residues in milk. For this purpose, the sensitivity of YCT for 15 antibiotics were determined. For each drug, 8 concentrations were tested. The detection limits of YCT at 2.5 h and 4 h incubation were determined (microg kg(-1)): 15 and 37.5, penicillin G; 4 and 5, ampicillin; 5 and 7.5, amoxycillin; 100 and 200, cephalexin; 80 and 100, cefazoline; 100 and 200, oxytetracycline; 500 and 100, chlortetracycline; 100 and 200, tetracycline; 150 and 200, doxycycline; 200 and 400, sulphadimidine; 500 and 1000, gentamycin; 1000 and 1500, spectinomycin; 400 and 500, erythromycin; 50 and 100, tylosin; 5000 and 10000, chloramphenicol. The YCT detection limits at 2.5 h incubation for ampicillin, cephalexin, tetracycline, oxytetracycline and tylosin are similar to those obtained as Maximum Residue Limit (MRL) according to Regulation 2377/90 EEC as set out by the European Union. In addition the detection limits of YCT for some antibiotics were lower than some of microbial inhibitor test.

  10. Widespread functional anoxia in the oxygen minimum zone of the Eastern South Pacific

    Science.gov (United States)

    Thamdrup, Bo; Dalsgaard, Tage; Revsbech, Niels Peter

    Oxygen minimum zones (OMZs) as found in the Eastern Pacific and Indian Ocean are biogeochemical hot spots with a disproportionately large role in the marine nitrogen cycle, and they are important components of the highly productive ecosystems in which they occur. Although the oxygen-depleted waters have been known for a century, oxygen levels inside them are not well constrained and the regulation of their anaerobic processes by oxygen is poorly understood. We deployed highly sensitive STOX oxygen sensors with a detection limit of 10 nmol kg-1 in combination with conventional hydrographic oxygen sensors along a cruise track transecting the Eastern South Pacific OMZ from South to North along the coast of Chile and Peru. Oxygen was below the detection limit throughout the ˜200 m thick OMZ core in most casts with STOX sensors. The only exception was an offshore location off Peru where oxygen was 10-50 nmol kg-1 in the core, likely as the result of a transient intrusion. Oxygen was also not detected in the OMZ core in further casts with conventional sensors, which had a detection limit of 90 nmol kg-1 after STOX-based zero calibration. Our measurements tighten the constraints on typical oxygen concentrations in the inner part of the OMZ by at least an order of magnitude relative to previous reports. Nitrite only accumulated when oxygen was depleted below 50 nmol kg-1, which indicates that nitrogen cycling is much more sensitive to oxygen than previously estimated. We argue that extreme oxygen depletion to low nanomalar or even picomolar concentrations is a normal condition in the South Pacific OMZ, and suggest that the OMZ core is in fact functionally anoxic over wide regions for extended periods. Our results further indicate that oxygen dynamics in the low nanomolar range play an important role in OMZ biogeochemistry.

  11. Deformed special relativity with an energy barrier of a minimum speed

    International Nuclear Information System (INIS)

    Nassif, Claudio

    2011-01-01

    Full text: This research aims to introduce a new principle of symmetry in the flat space-time by means of the elimination of the classical idea of rest, and by including a universal minimum limit of speed in the quantum world. Such a limit, unattainable by the particles, represents a preferred inertial reference frame associated with a universal background field that breaks Lorentz symmetry. So there emerges a new relativistic dynamics where a minimum speed forms an inferior energy barrier. One of the interesting implications of the existence of such a minimum speed is that it prevents the absolute zero temperature for an ultracold gas, according to the third law of thermodynamics. So we will be able to provide a fundamental dynamical explanation for the third law by means of a connection between such a phenomenological law and the new relativistic dynamics with a minimum speed. In other words we say that our relevant investigation is with respect to the problem of the absolute zero temperature in the thermodynamics of an ideal gas. We have made a connection between the 3 rd law of Thermodynamics and the new dynamics with a minimum speed by means of a relation between the absolute zero temperature (T = 0 deg K) and a minimum average speed (V) for a gas with N particles (molecules or atoms). Since T = 0 deg K is thermodynamically unattainable, we have shown this is due to the impossibility of reaching V from the new dynamics standpoint. (author)

  12. Limited interlaboratory comparison of Schmallenberg virus antibody detection in serum samples

    DEFF Research Database (Denmark)

    van der Poel, W. H. M.; Cay, B.; Zientara, S.

    2014-01-01

    Eight veterinary institutes in seven different countries in Europe participated in a limited interlaboratory comparison trial to evaluate laboratory performances of Schmallenberg virus (SBV) antibody detection in serum. Seven different sheep sera and three different cattle sera were circulated, a...

  13. Detection limits for nanoparticles in solution with classical turbidity spectra

    Science.gov (United States)

    Le Blevennec, G.

    2013-09-01

    Detection of nanoparticles in solution is required to manage safety and environmental problems. Spectral transmission turbidity method has now been known for a long time. It is derived from the Mie Theory and can be applied to any number of spheres, randomly distributed and separated by large distance compared to wavelength. Here, we describe a method for determination of size, distribution and concentration of nanoparticles in solution using UV-Vis transmission measurements. The method combines Mie and Beer Lambert computation integrated in a best fit approximation. In a first step, a validation of the approach is completed on silver nanoparticles solution. Verification of results is realized with Transmission Electronic Microscopy measurements for size distribution and an Inductively Coupled Plasma Mass Spectrometry for concentration. In view of the good agreement obtained, a second step of work focuses on how to manage the concentration to be the most accurate on the size distribution. Those efficient conditions are determined by simple computation. As we are dealing with nanoparticles, one of the key points is to know what the size limits reachable are with that kind of approach based on classical electromagnetism. In taking into account the transmission spectrometer accuracy limit we determine for several types of materials, metals, dielectrics, semiconductors the particle size limit detectable by such a turbidity method. These surprising results are situated at the quantum physics frontier.

  14. Improvement of detection limits of PIXE by substrate signal reduction

    International Nuclear Information System (INIS)

    Beaulieu, S.; Nejedly, Z.; Campbell, J.L.; Edwards, G.C.; Dias, G.M.

    2002-01-01

    Limits of detection (LODs) for aerosol samples collected using PIXE International cascade impactors, were improved approximately 50% after reducing the cross-sectional area of the analytical beam based on results obtained from microscope photographs of aerosol deposits. Improvements in LODs were most noticeable for selected elements collected on the smaller stages of the impactor (stages 1-3)

  15. [Comparison of the "Trigger" tool with the minimum basic data set for detecting adverse events in general surgery].

    Science.gov (United States)

    Pérez Zapata, A I; Gutiérrez Samaniego, M; Rodríguez Cuéllar, E; Gómez de la Cámara, A; Ruiz López, P

    Surgery is a high risk for the occurrence of adverse events (AE). The main objective of this study is to compare the effectiveness of the Trigger tool with the Hospital National Health System registration of Discharges, the minimum basic data set (MBDS), in detecting adverse events in patients admitted to General Surgery and undergoing surgery. Observational and descriptive retrospective study of patients admitted to general surgery of a tertiary hospital, and undergoing surgery in 2012. The identification of adverse events was made by reviewing the medical records, using an adaptation of "Global Trigger Tool" methodology, as well as the (MBDS) registered on the same patients. Once the AE were identified, they were classified according to damage and to the extent to which these could have been avoided. The area under the curve (ROC) were used to determine the discriminatory power of the tools. The Hanley and Mcneil test was used to compare both tools. AE prevalence was 36.8%. The TT detected 89.9% of all AE, while the MBDS detected 28.48%. The TT provides more information on the nature and characteristics of the AE. The area under the curve was 0.89 for the TT and 0.66 for the MBDS. These differences were statistically significant (P<.001). The Trigger tool detects three times more adverse events than the MBDS registry. The prevalence of adverse events in General Surgery is higher than that estimated in other studies. Copyright © 2017 SECA. Publicado por Elsevier España, S.L.U. All rights reserved.

  16. Calculation of the detection limits for radionuclides identified in gamma-ray spectra based on post-processing peak analysis results.

    Science.gov (United States)

    Korun, M; Vodenik, B; Zorko, B

    2018-03-01

    A new method for calculating the detection limits of gamma-ray spectrometry measurements is presented. The method is applicable for gamma-ray emitters, irrespective of the influences of the peaked background, the origin of the background and the overlap with other peaks. It offers the opportunity for multi-gamma-ray emitters to calculate the common detection limit, corresponding to more peaks. The detection limit is calculated by approximating the dependence of the uncertainty in the indication on its value with a second-order polynomial. In this approach the relation between the input quantities and the detection limit are described by an explicit expression and can be easy investigated. The detection limit is calculated from the data usually provided by the reports of peak-analyzing programs: the peak areas and their uncertainties. As a result, the need to use individual channel contents for calculating the detection limit is bypassed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. The Unusual Minimum of Cycle 23: Observations and Interpretation

    Science.gov (United States)

    Martens, Petrus C.; Nandy, D.; Munoz-Jaramillo, A.

    2009-05-01

    The current minimum of cycle 23 is unusual in its long duration, the very low level to which Total Solar Irradiance (TSI) has fallen, and the small flux of the open polar fields. The deep minimum of TSI seems to be related to an unprecedented dearth of polar faculae, and hence to the small amount of open flux. Based upon surface flux transport models it has been suggested that the causes of these phenomena may be an unusually vigorous meridional flow, or even a deviation from Joy's law resulting in smaller Joy angles than usual for emerging flux in cycle 23. There is also the possibility of a connection with the recently inferred emergence in polar regions of bipoles that systematically defy Hale's law. Much speculation has been going on as to the consequences of this exceptional minimum: are we entering another global minimum, is this the end of the 80 year period of exceptionally high solar activity, or is this just a statistical hiccup? Dynamo simulations are underway that may help answer this question. As an aside it must be mentioned that the current minimum of TSI puts an upper limit in the TSI input for global climate simulations during the Maunder minimum, and that a possible decrease in future solar activity will result in a very small but not insignificant reduction in the pace of global warming.

  18. Minimum reporting standards for clinical research on groin pain in athletes

    DEFF Research Database (Denmark)

    Delahunt, Eamonn; Thorborg, Kristian; Khan, Karim M

    2015-01-01

    Groin pain in athletes is a priority area for sports physiotherapy and sports medicine research. Heterogeneous studies with low methodological quality dominate research related to groin pain in athletes. Low-quality studies undermine the external validity of research findings and limit the ability...... to generalise findings to the target patient population. Minimum reporting standards for research on groin pain in athletes are overdue. We propose a set of minimum reporting standards based on best available evidence to be utilised in future research on groin pain in athletes. Minimum reporting standards...... are provided in relation to: (1) study methodology, (2) study participants and injury history, (3) clinical examination, (4) clinical assessment and (5) radiology. Adherence to these minimum reporting standards will strengthen the quality and transparency of research conducted on groin pain in athletes...

  19. In vitro bioassays for detecting dioxin-like activity--application potentials and limits of detection, a review.

    Science.gov (United States)

    Eichbaum, Kathrin; Brinkmann, Markus; Buchinger, Sebastian; Reifferscheid, Georg; Hecker, Markus; Giesy, John P; Engwall, Magnus; van Bavel, Bert; Hollert, Henner

    2014-07-15

    Use of in vitro assays as screening tool to characterize contamination of a variety of environmental matrices has become an increasingly popular and powerful toolbox in the field of environmental toxicology. While bioassays cannot entirely substitute analytical methods such as gas chromatography-mass spectrometry (GC-MS), the increasing improvement of cell lines and standardization of bioassay procedures enhance their utility as bioanalytical pre-screening tests prior to more targeted chemical analytical investigations. Dioxin-receptor-based assays provide a holistic characterization of exposure to dioxin-like compounds (DLCs) by integrating their overall toxic potential, including potentials of unknown DLCs not detectable via e.g. GC-MS. Hence, they provide important additional information with respect to environmental risk assessment of DLCs. This review summarizes different in vitro bioassay applications for detection of DLCs and considers the comparability of bioassay and chemical analytically derived toxicity equivalents (TEQs) of different approaches and various matrices. These range from complex samples such as sediments through single reference to compound mixtures. A summary of bioassay derived detection limits (LODs) showed a number of current bioassays to be equally sensitive as chemical methodologies, but moreover revealed that most of the bioanalytical studies conducted to date did not report their LODs, which represents a limitation with regard to low potency samples. Copyright © 2014 Elsevier B.V. All rights reserved.

  20. Study of a charge-coupled device for high-energy-particle detection

    International Nuclear Information System (INIS)

    Bhuiya, A.H.

    1983-05-01

    This presentation is based on measurements made to evaluate the application of charge-coupled devices as detectors of high-energy particles. The experiment was performed with a Fairchild Linear 256-Cell CCD111 array (size 8μm x 17 μm/cell), utilizing a light source instead of a particle beam. It was observed that the minimum detectable signal was limited to approx. 488 electrons at -50 0 C, where the readout and exposure times were about 260 ms and 400 ms respectively. The transfer inefficiency of the CCD111 was determined to be approx. 10 -4 . It has been concluded that at a lower temperature (approx. -100 0 C) or with faster readout (approx. 10 ms), the CCD111 would be able to detect the total deposited energy of minimum-ionizing charged particles

  1. Method to Solve the Problem of the Radioactivity Detection in Environmental Samples. Characteristic Limits

    International Nuclear Information System (INIS)

    Gasco, C.; Martinez, M.; Heras, M.

    2009-01-01

    The problem of the detection or when the radioactivity can be considered as higher than the background using different measurement techniques has been the objective of several statistical studies and controversies. The detection limit and the critical limit were studied by Currie in year 1968 and used by radiochemistry laboratories considering different ways of calculation that introduced confusion and not correct implementations. In the last few years, and due to the increasing number of standardization processes on the field of radioactivity and accreditation, several international institutions have chosen to unify the criteria for using common determination of detection limits. The most used methods are those developed by MARLAP and International Standard Organization ISO (Standard-11929). In this report are summarised both standards doing a comparative study and giving some examples of how to apply these limits. In same cases, little differences in the uncertainty calculation have been observed but the final results have been concordant. A deeply study of these standards can be done consulting the web page of the American Labs that developed MARLAP or buying the original ISO standard ISO-11929 recently approved (2009). (Author) 17 refs

  2. Predictive inference for best linear combination of biomarkers subject to limits of detection.

    Science.gov (United States)

    Coolen-Maturi, Tahani

    2017-08-15

    Measuring the accuracy of diagnostic tests is crucial in many application areas including medicine, machine learning and credit scoring. The receiver operating characteristic (ROC) curve is a useful tool to assess the ability of a diagnostic test to discriminate between two classes or groups. In practice, multiple diagnostic tests or biomarkers are combined to improve diagnostic accuracy. Often, biomarker measurements are undetectable either below or above the so-called limits of detection (LoD). In this paper, nonparametric predictive inference (NPI) for best linear combination of two or more biomarkers subject to limits of detection is presented. NPI is a frequentist statistical method that is explicitly aimed at using few modelling assumptions, enabled through the use of lower and upper probabilities to quantify uncertainty. The NPI lower and upper bounds for the ROC curve subject to limits of detection are derived, where the objective function to maximize is the area under the ROC curve. In addition, the paper discusses the effect of restriction on the linear combination's coefficients on the analysis. Examples are provided to illustrate the proposed method. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  3. Minimum exposure limits and measured relationships between the vitamin D, erythema and international commission on non-ionizing radiation protection solar ultraviolet.

    Science.gov (United States)

    Downs, Nathan; Parisi, Alfio; Butler, Harry; Turner, Joanna; Wainwright, Lisa

    2015-01-01

    The International Commission on Non-Ionizing Radiation Protection (ICNIRP) has established guidelines for exposure to ultraviolet radiation in outdoor occupational settings. Spectrally weighted ICNIRP ultraviolet exposures received by the skin or eye in an 8 h period are limited to 30 J m(-2). In this study, the time required to reach the ICNIRP exposure limit was measured daily in 10 min intervals upon a horizontal plane at a subtropical Australian latitude over a full year and compared with the effective Vitamin D dose received to one-quarter of the available skin surface area for all six Fitzpatrick skin types. The comparison of measured solar ultraviolet exposures for the full range of sky conditions in the 2009 measurement period, including a major September continental dust event, show a clear relationship between the weighted ICNIRP and the effective vitamin D dose. Our results show that the horizontal plane ICNIRP ultraviolet exposure may be used under these conditions to provide minimum guidelines for the healthy moderation of vitamin D, scalable to each of the six Fitzpatrick skin types. © 2014 The American Society of Photobiology.

  4. Are There Long-Run Effects of the Minimum Wage?

    Science.gov (United States)

    Sorkin, Isaac

    2015-04-01

    An empirical consensus suggests that there are small employment effects of minimum wage increases. This paper argues that these are short-run elasticities. Long-run elasticities, which may differ from short-run elasticities, are policy relevant. This paper develops a dynamic industry equilibrium model of labor demand. The model makes two points. First, long-run regressions have been misinterpreted because even if the short- and long-run employment elasticities differ, standard methods would not detect a difference using US variation. Second, the model offers a reconciliation of the small estimated short-run employment effects with the commonly found pass-through of minimum wage increases to product prices.

  5. Potential minimum cost of electricity of superconducting coil tokamak power reactors

    International Nuclear Information System (INIS)

    Reid, R.L.; Peng, Y-K. M.

    1989-01-01

    The potential minimum cost of electricity (COE) for superconducting tokamak power reactors is estimated by increasing the physics (confinement, beta limit, bootstrap current fraction) and technology [neutral beam energy, toroidal field (TF) coil allowable stresses, divertor heat flux, superconducting coil critical field, critical temperature, and quench temperature rise] constraints far beyond those assumed for ITER until the point of diminishing returns is reached. A version of the TETRA systems code, calibrated with the ITER design and modified for power reactors, is used for this analysis, limiting this study to reactors with the same basic device configuration and costing algorithms as ITER. A minimum COE is reduced from >200 to about 80 mill/kWh when the allowable design constraints are raised to 2 times those of ITER. At 4 times the ITER allowables, a minimum COE of about 60 mill/kWh is obtained. The corresponding tokamak has a major radius of approximately 4 m, a plasma current close to 10 MA, an aspect ratio of 4, a confinement H- factor ≤3, a beta limit of approximately 2 times the first stability regime, a divertor heat flux of about 20 MW/m 2 , a Β max ≤ 18 T, and a TF coil average current density about 3 times that of ITER. The design constraints that bound the minimum COE are the allowable stresses in the TF coil, the neutral beam energy, and the 99% bootstrap current (essentially free current drive). 14 refs., 4 figs., 2 tabs

  6. Decreasing of the detection limit for gamma-ray Spectrometry with the influence of sample treatment

    International Nuclear Information System (INIS)

    Karami, M.; Sadighzadeh, A.; Asgharizadeh, F.; Sardari, D.; Tavassoli, A.; Arbabi, A.; Hochaghani, O.

    2009-01-01

    Full text: In this study the ash method has been applied for environmental sample treatment in order to decrease of the detection limit in gamma-ray spectrometry for low level radioactivity measurements. Detection limit in gamma ray spectrometry is the smallest expectation value of the net counting rate that can be detected on given probabilities. The environmental test samples have been changed into ash using a suitable oven. The heating were made under controlled temperature to avoid the escape of some radionuclides such as radiocaesium. The ash samples were measured by high resolution gamma-ray spectrometry system. (author)

  7. Limit of sensitivity of low-background counting equipment

    International Nuclear Information System (INIS)

    Homann, S.G.

    1991-01-01

    The Hazards Control Department's Radiological Measurements Laboratory (RML) analyzes many types of sample media in support of the Laboratory's health and safety program. The Department has determined that the equation for the minimum limit of sensitivity, MDC(α,β) = 2.71 + 3.29 (r b t s ) 1/2 is also adequate for RML counting systems with very-low-background levels. This paper reviews the normal distribution case and address the special case of determining the limit of sensitivity of a counting system when the background count rate is well known and small. In the latter case, we must use an exact test procedure based on the binomial distribution. However, the error in using the normal distribution for calculating a detection system's limit of sensitivity is not significant even as the total observed number of counts approaches or equals zero. 2 refs., 4 figs

  8. 40 CFR Appendix B to Part 136 - Definition and Procedure for the Determination of the Method Detection Limit-Revision 1.11

    Science.gov (United States)

    2010-07-01

    ... calculated method detection limit. To insure that the estimate of the method detection limit is a good...) where: MDL = the method detection limit t(n-1,1- α=.99) = the students' t value appropriate for a 99... Determination of the Method Detection Limit-Revision 1.11 B Appendix B to Part 136 Protection of Environment...

  9. The Detection of Helicobacter hepaticus Using Whispering-Gallery Mode Microcavity Optical Sensors

    Directory of Open Access Journals (Sweden)

    Mark E. Anderson

    2015-08-01

    Full Text Available Current bacterial detection techniques are relatively slow, require bulky instrumentation, and usually require some form of specialized training. The gold standard for bacterial detection is culture testing, which can take several days to receive a viable result. Therefore, simpler detection techniques that are both fast and sensitive could greatly improve bacterial detection and identification. Here, we present a new method for the detection of the bacteria Helicobacter hepaticus using whispering-gallery mode (WGM optical microcavity-based sensors. Due to minimal reflection losses and low material adsorption, WGM-based sensors have ultra-high quality factors, resulting in high-sensitivity sensor devices. In this study, we have shown that bacteria can be non-specifically detected using WGM optical microcavity-based sensors. The minimum detection for the device was 1 × 104 cells/mL, and the minimum time of detection was found to be 750 s. Given that a cell density as low as 1 × 103 cells/mL for Helicobacter hepaticus can cause infection, the limit of detection shown here would be useful for most levels where Helicobacter hepaticus is biologically relevant. This study suggests a new approach for H. hepaticus detection using label-free optical sensors that is faster than, and potentially as sensitive as, standard techniques.

  10. Limits of detection of americium-241 in air

    International Nuclear Information System (INIS)

    Bereznai, T.

    1995-01-01

    Seven semiconductor detectors with various characteristics (type, form, size, etc.) were tested and compared in gamma-spectrometric assays for Am-241 aerosols in air. The problem at hand (determining a low activity or attaining a set detection limit (approx. 2 mBq/m 3 ) as soon as possible after sampling) was solved best by a large-volume n-type detector with a Be-window. In addition to the detector parameters commonly used (energy resolution and effectiveness), the peak-to-background ratio and the background counting rate at the gamma-energy of the nuclide to be determined are important criteria influencing the choice of equipment. (orig.) [de

  11. Physiological minimum temperatures for root growth in seven common European broad-leaved tree species.

    Science.gov (United States)

    Schenker, Gabriela; Lenz, Armando; Körner, Christian; Hoch, Günter

    2014-03-01

    Temperature is the most important factor driving the cold edge distribution limit of temperate trees. Here, we identified the minimum temperatures for root growth in seven broad-leaved tree species, compared them with the species' natural elevational limits and identified morphological changes in roots produced near their physiological cold limit. Seedlings were exposed to a vertical soil-temperature gradient from 20 to 2 °C along the rooting zone for 18 weeks. In all species, the bulk of roots was produced at temperatures above 5 °C. However, the absolute minimum temperatures for root growth differed among species between 2.3 and 4.2 °C, with those species that reach their natural distribution limits at higher elevations also tending to have lower thermal limits for root tissue formation. In all investigated species, the roots produced at temperatures close to the thermal limit were pale, thick, unbranched and of reduced mechanical strength. Across species, the specific root length (m g(-1) root) was reduced by, on average, 60% at temperatures below 7 °C. A significant correlation of minimum temperatures for root growth with the natural high elevation limits of the investigated species indicates species-specific thermal requirements for basic physiological processes. Although these limits are not necessarily directly causative for the upper distribution limit of a species, they seem to belong to a syndrome of adaptive processes for life at low temperatures. The anatomical changes at the cold limit likely hint at the mechanisms impeding meristematic activity at low temperatures.

  12. time of arrival 3-d position estimation using minimum ads-b receiver ...

    African Journals Online (AJOL)

    HOD

    The location from which a signal is transmitted can be estimated using the time it takes to be detected at a receiver. The difference between transmission time and the detection time is known as time of arrival (TOA). In this work, an algorithm for 3-dimensional (3-D) position estimation (PE) of an emitter using the minimum ...

  13. Detection and grading of dAVF: prospects and limitations of 3T MRI.

    Science.gov (United States)

    Bink, Andrea; Berkefeld, Joachim; Wagner, Marlies; You, Se-Jong; Ackermann, Hanns; Lorenz, Matthias W; Senft, Christian; du Mesnil de Rochemont, Richard

    2012-02-01

    DSA is currently the criterion standard for the assessment of dural arteriovenous fistulas (dAVF). Recently, evolving MRA techniques have emerged as a non-invasive alternative. The aim of this study is to assess the value of 3 T MRI in detecting and describing dAVF and to determine whether MRI can replace DSA as diagnostic procedure. A total of 19 patients with dAVF and 19 without dAVF underwent the same MRI protocol, including 3D time-of-flight MRA and time-resolved contrast-enhanced MRA. The images were evaluated retrospectively by three independent readers with different levels of experience blinded to clinical information. The readers assessed the presence, the site, the venous drainage and the feeders of dAVF. Sensitivity, specificity, accuracy, intertechnique and interobserver agreements were calculated. DAVF can be detected with high sensitivity, specificity and accuracy by experienced and also by less experienced readers. However, MRI has limitations when used for grading and evaluation of the angioarchitecture of the dAVF. Different experience, the limited resolution of MRI and its inability to selectively display arteries were the reasons for these limitations. With MRI dAVF can be detected reliably. Nevertheless, at present MRI can not fully replace DSA, especially for treatment planning.

  14. Setting a minimum age for juvenile justice jurisdiction in California.

    Science.gov (United States)

    S Barnert, Elizabeth; S Abrams, Laura; Maxson, Cheryl; Gase, Lauren; Soung, Patricia; Carroll, Paul; Bath, Eraka

    2017-03-13

    Purpose Despite the existence of minimum age laws for juvenile justice jurisdiction in 18 US states, California has no explicit law that protects children (i.e. youth less than 12 years old) from being processed in the juvenile justice system. In the absence of a minimum age law, California lags behind other states and international practice and standards. The paper aims to discuss these issues. Design/methodology/approach In this policy brief, academics across the University of California campuses examine current evidence, theory, and policy related to the minimum age of juvenile justice jurisdiction. Findings Existing evidence suggests that children lack the cognitive maturity to comprehend or benefit from formal juvenile justice processing, and diverting children from the system altogether is likely to be more beneficial for the child and for public safety. Research limitations/implications Based on current evidence and theory, the authors argue that minimum age legislation that protects children from contact with the juvenile justice system and treats them as children in need of services and support, rather than as delinquents or criminals, is an important policy goal for California and for other national and international jurisdictions lacking a minimum age law. Originality/value California has no law specifying a minimum age for juvenile justice jurisdiction, meaning that young children of any age can be processed in the juvenile justice system. This policy brief provides a rationale for a minimum age law in California and other states and jurisdictions without one.

  15. Bayesian-statistical decision threshold, detection limit, and confidence interval in nuclear radiation measurement

    International Nuclear Information System (INIS)

    Weise, K.

    1998-01-01

    When a contribution of a particular nuclear radiation is to be detected, for instance, a spectral line of interest for some purpose of radiation protection, and quantities and their uncertainties must be taken into account which, such as influence quantities, cannot be determined by repeated measurements or by counting nuclear radiation events, then conventional statistics of event frequencies is not sufficient for defining the decision threshold, the detection limit, and the limits of a confidence interval. These characteristic limits are therefore redefined on the basis of Bayesian statistics for a wider applicability and in such a way that the usual practice remains as far as possible unaffected. The principle of maximum entropy is applied to establish probability distributions from available information. Quantiles of these distributions are used for defining the characteristic limits. But such a distribution must not be interpreted as a distribution of event frequencies such as the Poisson distribution. It rather expresses the actual state of incomplete knowledge of a physical quantity. The different definitions and interpretations and their quantitative consequences are presented and discussed with two examples. The new approach provides a theoretical basis for the DIN 25482-10 standard presently in preparation for general applications of the characteristic limits. (orig.) [de

  16. Inductively coupled plasma emission spectrometric detection of simulated high performance liquid chromatographic peaks

    International Nuclear Information System (INIS)

    Fraley, D.M.; Yates, D.; Manahan, S.E.

    1979-01-01

    Because of its multielement capability, element-specificity, and low detection limits, inductively coupled plasma optical emission spectrometry (ICP) is a very promising technique for the detection of specific elemental species separated by high performance liquid chromatography (HPLC). This paper evaluated ICP as a detector for HPLC peaks containing specific elements. Detection limits for a number of elements have been evaluated in terms of the minimum detectable concentration of the element at the chromatographic peak maximum. The elements studies were Al, As, B, Ba, Ca, Cd, Co, Cr, Cu, Fe, K, Li, Mg, Mn, Mo, Na, Ni, P, Pb, Sb, Se, Sr, Ti, V, and Zn. In addition, ICP was compared with atomic absorption spectrometry for the detection of HPLC peaks composed of EDTA and NTA chelates of copper. Furthermore, ICP was compared to uv solution absorption for the detection of copper chelates. 6 figures, 4 tables

  17. Limits of detection in instrumental neutron activation analysis

    International Nuclear Information System (INIS)

    Guinn, V.P.

    1990-01-01

    Lower limits of detection (LLODs), frequently referred to simply as limits of detection and abbreviated as LODs, often appear in the literature of analytical chemistry - for numerous different methods of elemental and/or molecular analysis. In this chapter, one particular method of quantitative elemental analysis, that of instrumental neutron activation analysis (INAA), is the subject discussed, with reference to LODs. Particularly in the literature of neutron activation analysis (NAA), many tables of 'interference-free' NAA LODs are available. Not all of these are of much use, because (1) for many the definition used for LOD is not clear, or reasonable, (2) for many, the analysis conditions used are not clearly specified, and (3) for many, the analysis conditions used are specified, but not very practicable for most laboratories. For NAA work, such tables of interference-free LODs are, in any case, only applicable to samples in which, at the time of counting, only one radionuclide is present to any significant extent in the activated sample. It is important to note that tables of INAA LODs, per se, do not exist - since the LOD for a given element, under stated analysis conditions, can vary by orders of magnitude, depending on the elemental composition of the matrix in which it is present. For any given element, its INAA LOD will always be as large as, and usually much larger than, its tabulated 'interference-free' NAA LOD - how much larger depending upon the elemental composition of the matrix in which it is present. As discussed in this chapter, however, an INAA computer program exists that can calculate realistic INAA LODs for any elements of interest, in any kind of specified sample matrix, under any given set of analysis conditions

  18. N2 production rates limited by nitrite availability in the Bay of Bengal oxygen minimum zone

    Digital Repository Service at National Institute of Oceanography (India)

    Bristow, L.A; Callbeck, C.M.; Larsen, M.; Altabet, M.A; Dekaezemacker, J.; Forth, M.; Gauns, M.; Glud, R.N.; Kuypers, M.M.M.; Lavik, G.; Milucka, J.; Naqvi, S.W.A; Pratihary, A; Revsbech, N.P.; Thamdrup, B.; Treusch, A; Canfield, D.E.

    A third or more of the fixed nitrogen lost from the oceans as N2 is removed by anaerobic microbial processes in open ocean oxygen minimum zones. These zones have expanded over the past decades, and further anthropogenically induced...

  19. Do Minimum Wages Fight Poverty?

    OpenAIRE

    David Neumark; William Wascher

    1997-01-01

    The primary goal of a national minimum wage floor is to raise the incomes of poor or near-poor families with members in the work force. However, estimates of employment effects of minimum wages tell us little about whether minimum wages are can achieve this goal; even if the disemployment effects of minimum wages are modest, minimum wage increases could result in net income losses for poor families. We present evidence on the effects of minimum wages on family incomes from matched March CPS s...

  20. Gravitational wave detection using laser interferometry beyond the standard quantum limit

    Science.gov (United States)

    Heurs, M.

    2018-05-01

    Interferometric gravitational wave detectors (such as advanced LIGO) employ high-power solid-state lasers to maximize their detection sensitivity and hence their reach into the universe. These sophisticated light sources are ultra-stabilized with regard to output power, emission frequency and beam geometry; this is crucial to obtain low detector noise. However, even when all laser noise is reduced as far as technically possible, unavoidable quantum noise of the laser still remains. This is a consequence of the Heisenberg Uncertainty Principle, the basis of quantum mechanics: in this case, it is fundamentally impossible to simultaneously reduce both the phase noise and the amplitude noise of a laser to arbitrarily low levels. This fact manifests in the detector noise budget as two distinct noise sources-photon shot noise and quantum radiation pressure noise-which together form a lower boundary for current-day gravitational wave detector sensitivities, the standard quantum limit of interferometry. To overcome this limit, various techniques are being proposed, among them different uses of non-classical light and alternative interferometer topologies. This article explains how quantum noise enters and manifests in an interferometric gravitational wave detector, and gives an overview of some of the schemes proposed to overcome this seemingly fundamental limitation, all aimed at the goal of higher gravitational wave event detection rates. This article is part of a discussion meeting issue `The promises of gravitational-wave astronomy'.

  1. Modeling an Application's Theoretical Minimum and Average Transactional Response Times

    Energy Technology Data Exchange (ETDEWEB)

    Paiz, Mary Rose [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-04-01

    The theoretical minimum transactional response time of an application serves as a ba- sis for the expected response time. The lower threshold for the minimum response time represents the minimum amount of time that the application should take to complete a transaction. Knowing the lower threshold is beneficial in detecting anomalies that are re- sults of unsuccessful transactions. On the converse, when an application's response time falls above an upper threshold, there is likely an anomaly in the application that is causing unusual performance issues in the transaction. This report explains how the non-stationary Generalized Extreme Value distribution is used to estimate the lower threshold of an ap- plication's daily minimum transactional response time. It also explains how the seasonal Autoregressive Integrated Moving Average time series model is used to estimate the upper threshold for an application's average transactional response time.

  2. Study on minimum heat-flux point during boiling heat transfer on horizontal plates

    International Nuclear Information System (INIS)

    Nishio, Shigefumi

    1985-01-01

    The characteristics of boiling heat transfer are usually shown by the boiling curve of N-shape having the maximum and minimum points. As for the limiting heat flux point, that is, the maximum point, there have been many reports so far, as it is related to the physical burn of heat flux-controlling type heating surfaces. But though the minimum heat flux point is related to the quench point as the problems in steel heat treatment, the core safety of LWRs, the operational stability of superconducting magnets, the start-up characteristics of low temperature machinery, the condition of vapor explosion occurrence and so on, the systematic information has been limited. In this study, the effects of transient property and the heat conductivity of heating surfaces on the minimum heat flux condition in the pool boiling on horizontal planes were experimentally examined by using liquid nitrogen. The experimental apparatuses for steady boiling, for unsteady boiling with a copper heating surface, and for unsteady boiling with a heating surface other than copper were employed. The boiling curves obtained with these apparatuses and the minimum heat flux point condition are discussed. (Kako, I.)

  3. N2 production rates limited by nitrite availability in the Bay of Bengal oxygen minimum zone

    DEFF Research Database (Denmark)

    Bristow, Laura A.; Callbeck, C. M.; Larsen, M

    2017-01-01

    with isotopically labelled nitrogen compounds and analyse geochemical signatures of these processes in the water column. We find that the Bay of Bengal supports denitrifier and anammox microbial populations, mediating low, but significant N loss. Yet, unlike other oxygen minimum zones, our measurements using...

  4. Setting a minimum age for juvenile justice jurisdiction in California

    Science.gov (United States)

    Barnert, Elizabeth S.; Abrams, Laura S.; Maxson, Cheryl; Gase, Lauren; Soung, Patricia; Carroll, Paul; Bath, Eraka

    2018-01-01

    Purpose Despite the existence of minimum age laws for juvenile justice jurisdiction in 18 US states, California has no explicit law that protects children (i.e. youth less than 12 years old) from being processed in the juvenile justice system. In the absence of a minimum age law, California lags behind other states and international practice and standards. The paper aims to discuss these issues. Design/methodology/approach In this policy brief, academics across the University of California campuses examine current evidence, theory, and policy related to the minimum age of juvenile justice jurisdiction. Findings Existing evidence suggests that children lack the cognitive maturity to comprehend or benefit from formal juvenile justice processing, and diverting children from the system altogether is likely to be more beneficial for the child and for public safety. Research limitations/implications Based on current evidence and theory, the authors argue that minimum age legislation that protects children from contact with the juvenile justice system and treats them as children in need of services and support, rather than as delinquents or criminals, is an important policy goal for California and for other national and international jurisdictions lacking a minimum age law. Originality/value California has no law specifying a minimum age for juvenile justice jurisdiction, meaning that young children of any age can be processed in the juvenile justice system. This policy brief provides a rationale for a minimum age law in California and other states and jurisdictions without one. Paper type Conceptual paper PMID:28299968

  5. 40 CFR Figure C-4 to Subpart C of... - Illustration of the Minimum Limits for Correlation Coefficient for PM2.5 and PM10−2.5 Class II...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Illustration of the Minimum Limits for Correlation Coefficient for PM2.5 and PM10â2.5 Class II and III Methods C Figure C-4 to Subpart C of Part 53... Methods and Reference Methods Pt. 53, Subpt. C, Fig. C-4 Figure C-4 to Subpart C of Part 53—Illustration...

  6. Investigation of a gamma sensitive Ge-detector with Marinelligeometry. Determination of the detection limits

    International Nuclear Information System (INIS)

    Moricz, P.

    1984-01-01

    Different Marinelli geometries have been compared with a 180 ml standard plastic breaker geometry as a reference. The results show that the Marinelli geometries are the best. E.g. the detection limit with a Marinelli geometry of 0.5 l is only half compared with the limit when the standard geometry is used. (Edv)

  7. The influence of gender and bruxism on human minimum interdental threshold ability

    Directory of Open Access Journals (Sweden)

    Patrícia dos Santos Calderon

    2009-06-01

    Full Text Available OBJECTIVE: To evaluate the influence of gender and bruxism on the ability to discriminate minimum interdental threshold. MATERIAL AND METHODS: One hundred and fifteen individuals, representing both genders, bruxers and non-bruxers, with a mean age of 23.64 years, were selected for this study. For group allocation, every individual was subjected to a specific physical examination to detect bruxism (performed by three different examiners. Evaluation of the ability to discriminate minimum interdental threshold was performed using industrialized 0.010 mm-, 0.024 mm-, 0.030 mm-, 0.050 mm-, 0.080 mm- and 0.094 mm-thick aluminum foils that were placed between upper and lower premolars. Data were analyzed statistically by multiple linear regression analysis at 5% significance level. RESULTS: Neither gender nor bruxism influenced the ability to discriminate minimum interdental threshold (p>0.05. CONCLUSIONS: Gender and the presence of bruxism do not play a role in the minimum interdental threshold.

  8. Rising above the Minimum Wage.

    Science.gov (United States)

    Even, William; Macpherson, David

    An in-depth analysis was made of how quickly most people move up the wage scale from minimum wage, what factors influence their progress, and how minimum wage increases affect wage growth above the minimum. Very few workers remain at the minimum wage over the long run, according to this study of data drawn from the 1977-78 May Current Population…

  9. Trace element analysis by EPMA in geosciences: detection limit, precision and accuracy

    Science.gov (United States)

    Batanova, V. G.; Sobolev, A. V.; Magnin, V.

    2018-01-01

    Use of the electron probe microanalyser (EPMA) for trace element analysis has increased over the last decade, mainly because of improved stability of spectrometers and the electron column when operated at high probe current; development of new large-area crystal monochromators and ultra-high count rate spectrometers; full integration of energy-dispersive / wavelength-dispersive X-ray spectrometry (EDS/WDS) signals; and the development of powerful software packages. For phases that are stable under a dense electron beam, the detection limit and precision can be decreased to the ppm level by using high acceleration voltage and beam current combined with long counting time. Data on 10 elements (Na, Al, P, Ca, Ti, Cr, Mn, Co, Ni, Zn) in olivine obtained on a JEOL JXA-8230 microprobe with tungsten filament show that the detection limit decreases proportionally to the square root of counting time and probe current. For all elements equal or heavier than phosphorus (Z = 15), the detection limit decreases with increasing accelerating voltage. The analytical precision for minor and trace elements analysed in olivine at 25 kV accelerating voltage and 900 nA beam current is 4 - 18 ppm (2 standard deviations of repeated measurements of the olivine reference sample) and is similar to the detection limit of corresponding elements. To analyse trace elements accurately requires careful estimation of background, and consideration of sample damage under the beam and secondary fluorescence from phase boundaries. The development and use of matrix reference samples with well-characterised trace elements of interest is important for monitoring and improving of the accuracy. An evaluation of the accuracy of trace element analyses in olivine has been made by comparing EPMA data for new reference samples with data obtained by different in-situ and bulk analytical methods in six different laboratories worldwide. For all elements, the measured concentrations in the olivine reference sample

  10. Analytical review of minimum critical mass values for selected uranium and plutonium materials

    International Nuclear Information System (INIS)

    Morman, J.A.; Henrikson, D.J.; Garcia, A.S.

    1997-01-01

    Current subcritical limits for a number of uranium and plutonium materials (metals and compounds) as given in the ANSI/ANS standards for criticality safety are based on evaluations performed in the late 1970s and early 1980s. This paper presents the results of an analytical study of the minimum critical mass values for a set of materials using current codes and standard cross section sets. This work is meant to produce a consistent set of minimum critical mass values that can form the basis for adding new materials to the single-parameter tables in ANSI/ANS-8.1. Minimum critical mass results are presented for bare and water reflected full-density spheres and for full density moist (1.5 wt-% water) as calculated with KENO-Va, MCNP4A and ONEDANT. Calculations were also performed for both dry and moist materials at one-half density. Some KENO calculations were repeated using several cross section sets to examine potential bias differences. The results of the calculations were compared to the currently accepted subcritical limits. The calculated minimum critical mass values are reasonably consistent for the three codes, and differences most likely reflect differences in the cross section sets. The results are also consistent with values given in ANSI/ANS-8.1. 3 refs., 2 tabs

  11. Application of Statistical Methods to Activation Analytical Results near the Limit of Detection

    DEFF Research Database (Denmark)

    Heydorn, Kaj; Wanscher, B.

    1978-01-01

    Reporting actual numbers instead of upper limits for analytical results at or below the detection limit may produce reliable data when these numbers are subjected to appropriate statistical processing. Particularly in radiometric methods, such as activation analysis, where individual standard...... deviations of analytical results may be estimated, improved discrimination may be based on the Analysis of Precision. Actual experimental results from a study of the concentrations of arsenic in human skin demonstrate the power of this principle....

  12. TXRF 'measurements' of concentration distribution below the detection limit

    International Nuclear Information System (INIS)

    Kubala-Kukus, A.; Banas, D.; Braziewicz, J.; Majewska, U.; Mrowczynski, S.; Pajek, M.

    2000-01-01

    We demonstrate that a shape of the concentration distribution of the element in a set of samples, as measured by the TXRF method, can be determined even for the concentrations below the detection limit (DL). This can be done, when the measurements reporting the concentration below DL level are included properly in the analysis of the results. The method developed for such correction is presented and discussed. It is demonstrated that this correction is particularly important when the studied concentrations are close to the DL level of the method, which is a common case for TXRF. In the paper a precision of the developed correction is discussed in details, by using the results of numerical simulations of experiments for different concentration distributions and number of performed measurements. It is demonstrated that the factor, which limits the accuracy of the correction, is the number of measurements, not the correction procedure itself. The applicability and importance of the developed correction is demonstrated for routine TXRF analysis of different types of samples of bio-medical interest. (author)

  13. Investigation on feasibility and detection limits for determination of coating film thickness by neutron activation analysis

    International Nuclear Information System (INIS)

    Yao Maoying; Xu Jiayun; Zhang Dida; Yang Zunyong; Yao Zhenqiang; Wang Mingqiu; Gao Dangzhong

    2010-01-01

    A method for the determination of coating film thickness by neutron activation was proposed in this paper. After Au, Al and Cu et al.films were activated with a Am-Be neutron source, the characteristic γ-rays emitted by the activated nuclides in the films were counted with a HPGe γ spectrometer. The detection limits of film thickness by using a nuclear reactor neutron source were deduced on the basis of the γ-ray counts and the Monte-Carlo simulated detection efficiencies. The possible detection limits are typically 4-5 orders of magnitude better than those by fluorescent X-ray method, which is currently widely used to determine coating film thickness. (authors)

  14. Evaluation of a single-item screening question to detect limited health literacy in peritoneal dialysis patients.

    Science.gov (United States)

    Jain, Deepika; Sheth, Heena; Bender, Filitsa H; Weisbord, Steven D; Green, Jamie A

    2014-01-01

    Studies have shown that a single-item question might be useful in identifying patients with limited health literacy. However, the utility of the approach has not been studied in patients receiving maintenance peritoneal dialysis (PD). We assessed health literacy in a cohort of 31 PD patients by administering the Rapid Estimate of Adult Literacy in Medicine (REALM) and a single-item health literacy (SHL) screening question "How confident are you filling out medical forms by yourself?" (Extremely, Quite a bit, Somewhat, A little bit, or Not at all). To determine the accuracy of the single-item question for detecting limited health literacy, we performed sensitivity and specificity analyses of the SHL and plotted the area under the receiver operating characteristic (AUROC) curve using the REALM as a reference standard. Using a cut-off of "Somewhat" or less confident, the sensitivity of the SHL for detecting limited health literacy was 80%, and the specificity was 88%. The positive likelihood ratio was 6.9. The SHL had an AUROC of 0.79 (95% confidence interval: 0.52 to 1.00). Our results show that the SHL could be effective in detecting limited health literacy in PD patients.

  15. Employment effects of minimum wages

    OpenAIRE

    Neumark, David

    2014-01-01

    The potential benefits of higher minimum wages come from the higher wages for affected workers, some of whom are in low-income families. The potential downside is that a higher minimum wage may discourage employers from using the low-wage, low-skill workers that minimum wages are intended to help. Research findings are not unanimous, but evidence from many countries suggests that minimum wages reduce the jobs available to low-skill workers.

  16. RCRA materials analysis by laser-induced breakdown spectroscopy: Detection limits in soils

    International Nuclear Information System (INIS)

    Koskelo, A.; Cremers, D.A.

    1994-01-01

    The goal of the Technical Task Plan (TTP) that this report supports is research, development, testing and evaluation of a portable analyzer for RCRA and other metals. The instrumentation to be built will be used for field-screening of soils. Data quality is expected to be suitable for this purpose. The data presented in this report were acquired to demonstrate the detection limits for laser-induced breakdown spectroscopy (LIBS) of soils using instrument parameters suitable for fieldable instrumentation. The data are not expected to be the best achievable with the high pulse energies available in laboratory lasers. The report presents work to date on the detection limits for several elements in soils using LIBS. The elements targeted in the Technical Task Plan are antimony, arsenic, beryllium, cadmium, chromium, lead, selenium, and zirconium. Data for these elements are presented in this report. Also included are other data of interest to potential customers for the portable LIBS apparatus. These data are for barium, mercury, cesium and strontium. Data for uranium and thorium will be acquired during the tasks geared toward mixed waste characterization

  17. Minimum depth of investigation for grounded-wire TEM due to self-transients

    Science.gov (United States)

    Zhou, Nannan; Xue, Guoqiang

    2018-05-01

    The grounded-wire transient electromagnetic method (TEM) has been widely used for near-surface metalliferous prospecting, oil and gas exploration, and hydrogeological surveying in the subsurface. However, it is commonly observed that such TEM signal is contaminated by the self-transient process occurred at the early stage of data acquisition. Correspondingly, there exists a minimum depth of investigation, above which the observed signal is not applicable for reliable data processing and interpretation. Therefore, for achieving a more comprehensive understanding of the TEM method, it is necessary to perform research on the self-transient process and moreover develop an approach for quantifying the minimum detection depth. In this paper, we first analyze the temporal procedure of the equivalent circuit of the TEM method and present a theoretical equation for estimating the self-induction voltage based on the inductor of the transmitting wire. Then, numerical modeling is applied for building the relationship between the minimum depth of investigation and various properties, including resistivity of the earth, offset, and source length. It is guide for the design of survey parameters when the grounded-wire TEM is applied to the shallow detection. Finally, it is verified through applications to a coal field in China.

  18. Power-limited low-thrust trajectory optimization with operation point detection

    Science.gov (United States)

    Chi, Zhemin; Li, Haiyang; Jiang, Fanghua; Li, Junfeng

    2018-06-01

    The power-limited solar electric propulsion system is considered more practical in mission design. An accurate mathematical model of the propulsion system, based on experimental data of the power generation system, is used in this paper. An indirect method is used to deal with the time-optimal and fuel-optimal control problems, in which the solar electric propulsion system is described using a finite number of operation points, which are characterized by different pairs of thruster input power. In order to guarantee the integral accuracy for the discrete power-limited problem, a power operation detection technique is embedded in the fourth-order Runge-Kutta algorithm with fixed step. Moreover, the logarithmic homotopy method and normalization technique are employed to overcome the difficulties caused by using indirect methods. Three numerical simulations with actual propulsion systems are given to substantiate the feasibility and efficiency of the proposed method.

  19. A comparison of six software packages for evaluation of solid lung nodules using semi-automated volumetry: What is the minimum increase in size to detect growth in repeated CT examinations

    International Nuclear Information System (INIS)

    Hoop, Bartjan de; Gietema, Hester; Prokop, Mathias; Ginneken, Bram van; Zanen, Pieter; Groenewegen, Gerard

    2009-01-01

    We compared interexamination variability of CT lung nodule volumetry with six currently available semi-automated software packages to determine the minimum change needed to detect the growth of solid lung nodules. We had ethics committee approval. To simulate a follow-up examination with zero growth, we performed two low-dose unenhanced CT scans in 20 patients referred for pulmonary metastases. Between examinations, patients got off and on the table. Volumes of all pulmonary nodules were determined on both examinations using six nodule evaluation software packages. Variability (upper limit of the 95% confidence interval of the Bland-Altman plot) was calculated for nodules for which segmentation was visually rated as adequate. We evaluated 214 nodules (mean diameter 10.9 mm, range 3.3 mm-30.0 mm). Software packages provided adequate segmentation in 71% to 86% of nodules (p < 0.001). In case of adequate segmentation, variability in volumetry between scans ranged from 16.4% to 22.3% for the various software packages. Variability with five to six software packages was significantly less for nodules ≥8 mm in diameter (range 12.9%-17.1%) than for nodules <8 mm (range 18.5%-25.6%). Segmented volumes of each package were compared to each of the other packages. Systematic volume differences were detected in 11/15 comparisons. This hampers comparison of nodule volumes between software packages. (orig.)

  20. Limit analysis and design of containment vessels

    International Nuclear Information System (INIS)

    Save, M.

    1984-01-01

    In the introduction, the theory of plastic analysis of shells is briefly recalled. Minimum-volume design for assigned load factor at plastic collapse is then considered and optimality criteria are derived for plates and shells of continuously varying or piecewise-constant thickness. In the first part, containers made of metal are examined. Analytical and numerical limit analysis solutions and corresponding experimental results are considered for various types of vessels, including intersecting shells. Attention is given to experimental post-yield behavior. Some tests up to fracture are discussed. New theoretical and experimental results of limit analysis of stiffened cylindrical vessels are presented, in which reinforcing rings are treated as discrete structural element (no smearing out) and due account is taken of their strong curvature. Cases of collapse by instability under internal pressure are pointed out. Minimum-volume design of circular plates and cylindrical shells is then formulated and various examples are presented of sandwich and solid metal structures. Containers of piecewise-constant thickness are given particular attention. Available experimental evidence on minimum-volume design of plates and shells is reviewed and commented upon. The second part deals with reinforced concrete vessels. Cylindrical containers are studied, from both points of view of limit analysis and of limit design with minimum volume of reinforcement. The practical use of the latter solutions is discussed. A third part reviews other loading cases (including cyclic and impact loads) and gives indications on corresponding theories, formulations and solution methods. The last part is devoted to a discussion of the limitations of the methods presented, within the frame of the 'limit states' design philosophy, which is first briefly recalled. Considerations on further research in the field conclude the paper. (orig.)

  1. STATISTICAL METHODS FOR ENVIRONMENTAL APPLICATIONS USING DATA SETS WITH BELOW DETECTION LIMIT OBSERVATIONS AS INCORPORTED IN PROUCL 4.0

    Science.gov (United States)

    Nondetect (ND) or below detection limit (BDL) results cannot be measured accurately, and, therefore, are reported as less than certain detection limit (DL) values. However, since the presence of some contaminants (e.g., dioxin) in environmental media may pose a threat to human he...

  2. CARIES DETECTION WITH LASER FLUORESCENCE DEVICES. LIMITATIONS OF THEIR USE

    Directory of Open Access Journals (Sweden)

    Andreas Spaveras

    2017-03-01

    Data synthesis: DD and DDPen are useful devices for caries detection on the occlusal tooth surfaces. Their main advantages are the very high reproducibility of measurements (>0.90, the ease of handling and the quantification and monitoring capacity. Their main limitations are the relatively low specificity for enamel lesions, the necessity of unstained surfaces and absence of plaque and pastes during measurements and the absence of a universal, clinically functional calibration value (COV. Conclusion: Further studies are required for more reliable data analysis and clinical interpretation of the relevant results.

  3. Proposal for a methodology for the determination of the Detection Limit: Case of bulks detector for the Chlorothalonil

    International Nuclear Information System (INIS)

    Gonzalez G, J.; Parra M, C.M.; Romero R, R.M.

    1998-01-01

    As it usually found in the literature, the Lower Detection Limit for an analytical method is obtained by means of a simple statistical exercise whose value is seldom attained in practice. For this reason a method was designed for achieving a Practical Lower Detection Limit for the lowest concentration of the compound that could be detected, S= 2 R, with a probability of at least, 0.90. A methodological design was formulated to get a Practical Lower Detection Limit that is not timed consuming for the analyst. It is presented using an example and, additionally its benefits are discussed versus the unattainable values that are obtained by the traditional use of the standard deviation of a series of measurements of the compound at concentrations near zero, which is then multiplied by the t student for a one tailed test for n-1 degrees of freedom

  4. Minimum Wages and Poverty

    OpenAIRE

    Fields, Gary S.; Kanbur, Ravi

    2005-01-01

    Textbook analysis tells us that in a competitive labor market, the introduction of a minimum wage above the competitive equilibrium wage will cause unemployment. This paper makes two contributions to the basic theory of the minimum wage. First, we analyze the effects of a higher minimum wage in terms of poverty rather than in terms of unemployment. Second, we extend the standard textbook model to allow for incomesharing between the employed and the unemployed. We find that there are situation...

  5. Minimum number of transfer units and reboiler duty for multicomponent distillation columns

    International Nuclear Information System (INIS)

    Pleşu, Valentin; Bonet Ruiz, Alexandra Elena; Bonet, Jordi; Llorens, Joan; Iancu, Petrica

    2013-01-01

    Some guidelines to evaluate distillation columns, considering only basic thermodynamic data and principles, are provided in this paper. The method allows a first insight to the problem by simple calculations, without requiring column variables to ensure rational use of energy and low environmental impact. The separation system is approached by two complementary ways: minimum and infinite reflux flow rate. The minimum reflux provides the minimum energy requirements, and the infinite reflux provides the feasibility conditions. The difficulty of separation can be expressed in terms of number of transfer units (NTU). The applicability of the method is not mathematically limited by the number of components in the mixture. It is also applicable to reactive distillation. Several mixtures, including reactive distillation, are rigorously simulated as illustrative examples, to verify the applicability of the approach. The separation of the mixtures, performed by distillation columns, is feasible if a minimum NTU can be calculated between the distillate and bottom products. Once verified the feasibility of the separation, the maximum thermal efficiency depends only on boiling point of bottom and distillate streams. The minimum energy requirements corresponding to the reboiler can be calculated from the maximum thermal efficiency, and the variation of entropy and enthalpy of mixing between distillate and bottom streams. -- Highlights: • Feasibility analysis complemented with difficulty of separation parameters • Minimum and infinite reflux simplified models for distillation columns • Minimum number of transfer units (NTU) for packed columns at early design stages • Calculation of minimum energy distillation requirements at early design stages • Thermodynamic cycle approach and efficiency for distillation columns

  6. 75 FR 6151 - Minimum Capital

    Science.gov (United States)

    2010-02-08

    ... capital and reserve requirements to be issued by order or regulation with respect to a product or activity... minimum capital requirements. Section 1362(a) establishes a minimum capital level for the Enterprises... entities required under this section.\\6\\ \\3\\ The Bank Act's current minimum capital requirements apply to...

  7. UNUSUAL TRENDS IN SOLAR P-MODE FREQUENCIES DURING THE CURRENT EXTENDED MINIMUM

    International Nuclear Information System (INIS)

    Tripathy, S. C.; Jain, K.; Hill, F.; Leibacher, J. W.

    2010-01-01

    We investigate the behavior of the intermediate-degree mode frequencies of the Sun during the current extended minimum phase to explore the time-varying conditions in the solar interior. Using contemporaneous helioseismic data from the Global Oscillation Network Group (GONG) and the Michelson Doppler Imager (MDI), we find that the changes in resonant mode frequencies during the activity minimum period are significantly greater than the changes in solar activity as measured by different proxies. We detect a seismic minimum in MDI p-mode frequency shifts during 2008 July-August but no such signature is seen in mean shifts computed from GONG frequencies. We also analyze the frequencies of individual oscillation modes from GONG data as a function of latitude and observe a signature of the onset of the solar cycle 24 in early 2009. Thus, the intermediate-degree modes do not confirm the onset of the cycle 24 during late 2007 as reported from the analysis of the low-degree Global Oscillations at Low Frequency frequencies. Further, both the GONG and MDI frequencies show a surprising anti-correlation between frequencies and activity proxies during the current minimum, in contrast to the behavior during the minimum between cycles 22 and 23.

  8. A Pareto-Improving Minimum Wage

    OpenAIRE

    Eliav Danziger; Leif Danziger

    2014-01-01

    This paper shows that a graduated minimum wage, in contrast to a constant minimum wage, can provide a strict Pareto improvement over what can be achieved with an optimal income tax. The reason is that a graduated minimum wage requires high-productivity workers to work more to earn the same income as low-productivity workers, which makes it more difficult for the former to mimic the latter. In effect, a graduated minimum wage allows the low-productivity workers to benefit from second-degree pr...

  9. Low-Cost Resonant Cavity Raman Gas Probe for Multi-Gas Detection

    Science.gov (United States)

    Thorstensen, J.; Haugholt, K. H.; Ferber, A.; Bakke, K. A. H.; Tschudi, J.

    2014-12-01

    Raman based gas sensing can be attractive in several industrial applications, due to its multi-gas sensing capabilities and its ability to detect O_2 and N_2. In this article, we have built a Raman gas probe, based on low-cost components, which has shown an estimated detection limit of 0.5 % for 30 second measurements of N_2 and O_2. While this detection limit is higher than that of commercially available equipment, our estimated component cost is approximately one tenth of the price of commercially available equipment. The use of a resonant Fabry-Pérot cavity increases the scattered signal, and hence the sensitivity, by a factor of 50. The cavity is kept in resonance using a piezo-actuated mirror and a photodiode in a feedback loop. The system described in this article was made with minimum-cost components to demonstrate the low-cost principle. However, it is possible to decrease the detection limit using a higher-powered (but still low-cost) laser and improving the collection optics. By applying these improvements, the detection limit and estimated measurement precision will be sufficient for e.g. the monitoring of input gases in combustion processes, such as e.g. (bio-)gas power plants. In these processes, knowledge about gas compositions with 0.1 % (absolute) precision can help regulate and optimize process conditions. The system has the potential to provide a low-cost, industrial Raman sensor that is optimized for specific gas-detection applications.

  10. Detection limits should be a thing of the past in gamma-ray spectrometry in general as well as in neutron activation analysis

    NARCIS (Netherlands)

    Blaauw, Menno

    2016-01-01

    In gamma-ray spectrometry with high-resolution detectors, full-energy peaks are often to be detected by a peak-search algorithm, with a threshold for detection. Detection limits can be derived from this. Detection limits are often computed along with measured activities or concentrations. When an

  11. Optimising Mycobacterium tuberculosis detection in resource limited settings.

    Science.gov (United States)

    Alfred, Nwofor; Lovette, Lawson; Aliyu, Gambo; Olusegun, Obasanya; Meshak, Panwal; Jilang, Tunkat; Iwakun, Mosunmola; Nnamdi, Emenyonu; Olubunmi, Onuoha; Dakum, Patrick; Abimiku, Alash'le

    2014-03-03

    The light-emitting diode (LED) fluorescence microscopy has made acid-fast bacilli (AFB) detection faster and efficient although its optimal performance in resource-limited settings is still being studied. We assessed the optimal performances of light and fluorescence microscopy in routine conditions of a resource-limited setting and evaluated the digestion time for sputum samples for maximum yield of positive cultures. Cross-sectional study. Facility-based involving samples of routine patients receiving tuberculosis treatment and care from the main tuberculosis case referral centre in northern Nigeria. The study included 450 sputum samples from 150 new patients with clinical diagnosis of pulmonary tuberculosis. The 450 samples were pooled into 150 specimens, examined independently with mercury vapour lamp (FM), LED CysCope (CY) and Primo Star iLED (PiLED) fluorescence microscopies, and with the Ziehl-Neelsen (ZN) microscopy to assess the performance of each technique compared with liquid culture. The cultured specimens were decontaminated with BD Mycoprep (4% NaOH-1% NLAC and 2.9% sodium citrate) for 10, 15 and 20 min before incubation in Mycobacterium growth incubator tube (MGIT) system and growth examined for acid-fast bacilli (AFB). Of the 150 specimens examined by direct microscopy: 44 (29%), 60 (40%), 49 (33%) and 64 (43%) were AFB positive by ZN, FM, CY and iLED microscopy, respectively. Digestion of sputum samples for 10, 15 and 20 min yielded mycobacterial growth in 72 (48%), 81 (54%) and 68 (45%) of the digested samples, respectively, after incubation in the MGIT system. In routine laboratory conditions of a resource-limited setting, our study has demonstrated the superiority of fluorescence microscopy over the conventional ZN technique. Digestion of sputum samples for 15 min yielded more positive cultures.

  12. Estimation of the limit of detection with a bootstrap-derived standard error by a partly non-parametric approach. Application to HPLC drug assays

    DEFF Research Database (Denmark)

    Linnet, Kristian

    2005-01-01

    Bootstrap, HPLC, limit of blank, limit of detection, non-parametric statistics, type I and II errors......Bootstrap, HPLC, limit of blank, limit of detection, non-parametric statistics, type I and II errors...

  13. Detection limits for real-time source water monitoring using indigenous freshwater microalgae

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez Jr, Miguel [ORNL; Greenbaum, Elias [ORNL

    2009-01-01

    This research identified toxin detection limits using the variable fluorescence of naturally occurring microalgae in source drinking water for five chemical toxins with different molecular structures and modes of toxicity. The five chemicals investigated were atrazine, Diuron, paraquat, methyl parathion, and potassium cyanide. Absolute threshold sensitivities of the algae for detection of the toxins in unmodified source drinking water were measured. Differential kinetics between the rate of action of the toxins and natural changes in algal physiology, such as diurnal photoinhibition, are significant enough that effects of the toxin can be detected and distinguished from the natural variance. This is true even for physiologically impaired algae where diminished photosynthetic capacity may arise from uncontrollable external factors such as nutrient starvation. Photoinhibition induced by high levels of solar radiation is a predictable and reversible phenomenon that can be dealt with using a period of dark adaption of 30 minutes or more.

  14. Limits of 2D-TCA in detecting BOLD responses to epileptic activity.

    Science.gov (United States)

    Khatamian, Yasha Borna; Fahoum, Firas; Gotman, Jean

    2011-05-01

    Two-dimensional temporal clustering analysis (2D-TCA) is a relatively new functional MRI (fMRI) based technique that breaks blood oxygen level dependent activity into separate components based on timing and has shown potential for localizing epileptic activity independently of electroencephalography (EEG). 2D-TCA has only been applied to detect epileptic activity in a few studies and its limits in detecting activity of various forms (i.e. activation size, amplitude, and frequency) have not been investigated. This study evaluated 2D-TCA's ability to detect various forms of both simulated epileptic activity and EEG-fMRI activity detected in patients. When applied to simulated data, 2D-TCA consistently detected activity in 6min runs containing 5 spikes/run, 10 spikes/run, and one 5s long event with hemodynamic response function amplitudes of at least 1.5%, 1.25%, and 1% above baseline respectively. When applied to patient data, while detection of interictal spikes was inconsistent, 2D-TCA consistently produced results similar to those obtained by EEG-fMRI when at least 2 prolonged interictal events (a few seconds each) occurred during the run. However, even for such cases it was determined that 2D-TCA can only be used to validate localization by other means or to create hypotheses as to where activity may occur, as it also detects changes not caused by epileptic activity. Copyright © 2011 Elsevier B.V. All rights reserved.

  15. Minimum critical mass systems

    International Nuclear Information System (INIS)

    Dam, H. van; Leege, P.F.A. de

    1987-01-01

    An analysis is presented of thermal systems with minimum critical mass, based on the use of materials with optimum neutron moderating and reflecting properties. The optimum fissile material distributions in the systems are obtained by calculations with standard computer codes, extended with a routine for flat fuel importance search. It is shown that in the minimum critical mass configuration a considerable part of the fuel is positioned in the reflector region. For 239 Pu a minimum critical mass of 87 g is found, which is the lowest value reported hitherto. (author)

  16. Simulated minimum detectable activity concentration (MDAC) for a real-time UAV airborne radioactivity monitoring system with HPGe and LaBr_3 detectors

    International Nuclear Information System (INIS)

    Tang, Xiao-Bin; Meng, Jia; Wang, Peng; Cao, Ye; Huang, Xi; Wen, Liang-Sheng; Chen, Da

    2016-01-01

    An automatic real-time UAV airborne radioactivity monitoring system with high-purity germanium (HPGe) and lanthanum bromide (LaBr_3) detectors (NH-UAV) was developed to precisely obtain small-scope nuclide information in major nuclear accidents. The specific minimum detectable activity concentration (MDAC) calculation method for NH-UAV in the atmospheric environment was deduced in this study for a priori evaluation and quantification of the suitability of NH-UAV in the Fukushima nuclear accident, where the MDAC values of this new equipment were calculated based on Monte Carlo simulation. The effects of radioactive source term size and activity concentration on the MDAC values were analyzed to assess the detection performance of NH-UAV in more realistic environments. Finally, the MDAC values were calculated at different shielding thicknesses of the HPGe detector to improve the detection capabilities of the HPGe detector, and the relationship between the MDAC and the acquisition time of the system was deduced. The MDAC calculation method and data results in this study may be used as a reference for in-situ radioactivity measurement of NH-UAV. - Highlights: • A real-time UAV airborne radioactivity monitoring system (NH-UAV) was developed. • The efficiency calculations and MDAC values are given. • NH-UAV is able to monitor major nuclear accidents, such as the Fukushima accident. • The source term size can influence the detection sensitivity of the system. • The HPGe detector possesses measurement thresholds on activity concentration.

  17. Mini-column assay for rapid detection of malachite green in fish.

    Science.gov (United States)

    Shalaby, Ali R; Emam, Wafaa H; Anwar, Mervat M

    2017-07-01

    A simple, rapid and economical mini-column method for detecting malachite green (MG) residue in fish was developed. The method used a column with 2mm ID that was tightly packed with silica gel followed by alumina. Detection of MG was performed by viewing the developed mini-column at visible light by naked eye; where MG was seen as compact green band at the confluence of the silica gel layer with alumina layer. The limit of detection of the assay was 2ng which conform the minimum required performance limit (MRPL). Evaluation utility of the method indicated that all blank and spiked samples at levels below MRPL were assessed as accepted. The intensity of the green band increased whenever MG level in the extract increased; indicated that suggested mini-column technique could be used for semi-quantitative determination of MG in fish samples. The method can be used to select the questionable samples. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea

    Energy Technology Data Exchange (ETDEWEB)

    Bowers, Robert M.; Kyrpides, Nikos C.; Stepanauskas, Ramunas; Harmon-Smith, Miranda; Doud, Devin; Reddy, T. B. K.; Schulz, Frederik; Jarett, Jessica; Rivers, Adam R.; Eloe-Fadrosh, Emiley A.; Tringe, Susannah G.; Ivanova, Natalia N.; Copeland, Alex; Clum, Alicia; Becraft, Eric D.; Malmstrom, Rex R.; Birren, Bruce; Podar, Mircea; Bork, Peer; Weinstock, George M.; Garrity, George M.; Dodsworth, Jeremy A.; Yooseph, Shibu; Sutton, Granger; Glöckner, Frank O.; Gilbert, Jack A.; Nelson, William C.; Hallam, Steven J.; Jungbluth, Sean P.; Ettema, Thijs J. G.; Tighe, Scott; Konstantinidis, Konstantinos T.; Liu, Wen-Tso; Baker, Brett J.; Rattei, Thomas; Eisen, Jonathan A.; Hedlund, Brian; McMahon, Katherine D.; Fierer, Noah; Knight, Rob; Finn, Rob; Cochrane, Guy; Karsch-Mizrachi, Ilene; Tyson, Gene W.; Rinke, Christian; Kyrpides, Nikos C.; Schriml, Lynn; Garrity, George M.; Hugenholtz, Philip; Sutton, Granger; Yilmaz, Pelin; Meyer, Folker; Glöckner, Frank O.; Gilbert, Jack A.; Knight, Rob; Finn, Rob; Cochrane, Guy; Karsch-Mizrachi, Ilene; Lapidus, Alla; Meyer, Folker; Yilmaz, Pelin; Parks, Donovan H.; Eren, A. M.; Schriml, Lynn; Banfield, Jillian F.; Hugenholtz, Philip; Woyke, Tanja

    2017-08-08

    We present two standards developed by the Genomic Standards Consortium (GSC) for reporting bacterial and archaeal genome sequences. Both are extensions of the Minimum Information about Any (x) Sequence (MIxS). The standards are the Minimum Information about a Single Amplified Genome (MISAG) and the Minimum Information about a Metagenome-Assembled Genome (MIMAG), including, but not limited to, assembly quality, and estimates of genome completeness and contamination. These standards can be used in combination with other GSC checklists, including the Minimum Information about a Genome Sequence (MIGS), Minimum Information about a Metagenomic Sequence (MIMS), and Minimum Information about a Marker Gene Sequence (MIMARKS). Community-wide adoption of MISAG and MIMAG will facilitate more robust comparative genomic analyses of bacterial and archaeal diversity.

  19. 5 CFR 551.301 - Minimum wage.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Minimum wage. 551.301 Section 551.301... FAIR LABOR STANDARDS ACT Minimum Wage Provisions Basic Provision § 551.301 Minimum wage. (a)(1) Except... employees wages at rates not less than the minimum wage specified in section 6(a)(1) of the Act for all...

  20. Detection Limits for Spectro-fluorometry: A Case Study in the Region of Finstersee, Canton Zug, Northern Switzerland

    Science.gov (United States)

    Otz, M. H.; Otz, H. K.; Keller, P.

    2002-05-01

    Synthetic fluorescent dyes, applied below the visual detection limit (< 0.1 mg/L), have been used as tracers of ground water flow paths since the beginning of the 1950s. Since 1965, we have used spectro-fluorometers with photomultipliers to measure low concentrations of fluorescent dyes in ground water in Switzerland. In collaboration with the Engineering Geology Department of the ETH, we have separated uranine at 0.1 ng/L and Na-naphtionate at 1 ng/L from background fluorescence of spring water in the Finstersee region. These values are 10-100 times lower than postulated detection limits in the literature. The use of low dye concentrations prevents a study region from being contaminated by increased background levels due to remnant dye within the aquifer, thereby leaving the region available for future dye tracing studies. Lower detection limits also can solve particular hydraulic problems where conventional methods fail and enhance the possibility for using artificial dyes in environmentally sensitive aquifer settings.

  1. Radiotracer technique for leakage detection under simulated conditions

    International Nuclear Information System (INIS)

    Yelgaonkar, V.N.; Sharma, V.K.; Tapase, A.S.

    2001-01-01

    Radiotracer techniques are often used to locate leaks in underground pipelines. An attempt was made to standardize radiotracer pulse migration in terms of minimum detectable limit. For this purpose a 6 inch diameter 1200 long steel pipe was used. Two leak rates viz. 10 litres per minute and 1 litre per minute with an accuracy of ± 10% were simulated. The experiments on this pipeline showed that this method could be used to locate a leak of the order of 1 litre per minute in a 6 inch diameter isolated underground pipeline. (author)

  2. Matrix effect on the detection limit and accuracy in total reflection X-ray fluorescence analysis of trace elements in environmental and biological samples

    International Nuclear Information System (INIS)

    Karjou, J.

    2007-01-01

    The effect of matrix contents on the detection limit of total reflection X-ray fluorescence analysis was experimentally investigated using a set of multielement standard solutions (500 ng/mL of each element) in variable concentrations of NH 4 NO 3 . It was found that high matrix concentration, i.e. 0.1-10% NH 4 NO 3 , had a strong effect on the detection limits for all investigated elements, whereas no effect was observed at lower matrix concentration, i.e. 0-0.1% NH 4 NO 3 . The effect of soil and blood sample masses on the detection limit was also studied. The results showed decreasing the detection limit (in concentration unit, μg/g) with increasing the sample mass. However, the detection limit increased (in mass unit, ng) with increasing sample mass. The optimal blood sample mass of ca. 200 μg was sufficient to improve the detection limit of Se determination by total reflection X-ray fluorescence. The capability of total reflection X-ray fluorescence to analyze different kinds of samples was discussed with respect to the accuracy and detection limits based on certified and reference materials. Direct analysis of unknown water samples from several sources was also presented in this work

  3. Detection limits of Legionella pneumophila in environmental samples after co-culture with Acanthamoeba polyphaga

    Science.gov (United States)

    2013-01-01

    Background The efficiency of recovery and the detection limit of Legionella after co-culture with Acanthamoeba polyphaga are not known and so far no investigations have been carried out to determine the efficiency of the recovery of Legionella spp. by co-culture and compare it with that of conventional culturing methods. This study aimed to assess the detection limits of co-culture compared to culture for Legionella pneumophila in compost and air samples. Compost and air samples were spiked with known concentrations of L. pneumophila. Direct culturing and co-culture with amoebae were used in parallel to isolate L. pneumophila and recovery standard curves for both methods were produced for each sample. Results The co-culture proved to be more sensitive than the reference method, detecting 102-103 L. pneumophila cells in 1 g of spiked compost or 1 m3 of spiked air, as compared to 105-106 cells in 1 g of spiked compost and 1 m3 of spiked air. Conclusions Co-culture with amoebae is a useful, sensitive and reliable technique to enrich L. pneumophila in environmental samples that contain only low amounts of bacterial cells. PMID:23442526

  4. Time-limited optimal dynamics beyond the Quantum Speed Limit

    DEFF Research Database (Denmark)

    Gajdacz, Miroslav; Das, Kunal K.; Arlt, Jan

    2015-01-01

    The quantum speed limit sets the minimum time required to transfer a quantum system completely into a given target state. At shorter times the higher operation speed has to be paid with a loss of fidelity. Here we quantify the trade-off between the fidelity and the duration in a system driven......-off expressed in terms of the direct Hilbert velocity provides a robust prediction of the quantum speed limit and allows to adapt the control optimization such that it yields a predefined fidelity. The results are verified numerically in a multilevel system with a constrained Hamiltonian, and a classification...

  5. The Impact of Including Below Detection Limit Samples in Post Decommissioning Soil Sample Analyses

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jung Hwan; Yim, Man-Sung [KAIST, Daejeon (Korea, Republic of)

    2016-10-15

    To meet the required standards the site owner has to show that the soil at the facility has been sufficiently cleaned up. To do this one must know the contamination of the soil at the site prior to clean up. This involves sampling that soil to identify the degree of contamination. However there is a technical difficulty in determining how much decontamination should be done. The problem arises when measured samples are below the detection limit. Regulatory guidelines for site reuse after decommissioning are commonly challenged because the majority of the activity in the soil at or below the limit of detection. Using additional statistical analyses of contaminated soil after decommissioning is expected to have the following advantages: a better and more reliable probabilistic exposure assessment, better economics (lower project costs) and improved communication with the public. This research will develop an approach that defines an acceptable method for demonstrating compliance of decommissioned NPP sites and validates that compliance. Soil samples from NPP often contain censored data. Conventional methods for dealing with censored data sets are statistically biased and limited in their usefulness. In this research, additional methods are performed using real data from a monazite manufacturing factory.

  6. Development of detection techniques for the Swedish noble gas sampler

    International Nuclear Information System (INIS)

    Ringbom, A.

    1998-11-01

    A short review on the radioactive properties of noble gas isotopes relevant for monitoring of nuclear activities is given, together with a brief discussion of the existing systems for detection of radioactive noble gases. A 4π detection system to be used in the automatic version of the Swedish noble gas sampling device is described. Monte Carlo calculations of the total gamma and beta efficiency for different detector designs have been performed, together with estimates of the resulting minimum detectable concentration (MDC). The estimated MDC values for detection of the 133g Xe 81 keV and the 135g Xe 250 keV gamma lines are around 0.3 mBq/m 3 in both cases. This is a factor of three lower than the detection limit required for a sampling station in the Comprehensive Nuclear-Test-Ban Treaty monitoring network. The possibility to modify the system to detect 85 Kr is also discussed

  7. Development of detection techniques for the Swedish noble gas sampler

    Energy Technology Data Exchange (ETDEWEB)

    Ringbom, A

    1998-11-01

    A short review on the radioactive properties of noble gas isotopes relevant for monitoring of nuclear activities is given, together with a brief discussion of the existing systems for detection of radioactive noble gases. A 4{pi} detection system to be used in the automatic version of the Swedish noble gas sampling device is described. Monte Carlo calculations of the total gamma and beta efficiency for different detector designs have been performed, together with estimates of the resulting minimum detectable concentration (MDC). The estimated MDC values for detection of the {sup 133g}Xe 81 keV and the {sup 135g}Xe 250 keV gamma lines are around 0.3 mBq/m{sup 3} in both cases. This is a factor of three lower than the detection limit required for a sampling station in the Comprehensive Nuclear-Test-Ban Treaty monitoring network. The possibility to modify the system to detect {sup 85}Kr is also discussed 27 refs, 13 figs, 3 tabs

  8. Theoretical detection threshold of the proton-acoustic range verification technique

    International Nuclear Information System (INIS)

    Ahmad, Moiz; Yousefi, Siavash; Xing, Lei; Xiang, Liangzhong

    2015-01-01

    Purpose: Range verification in proton therapy using the proton-acoustic signal induced in the Bragg peak was investigated for typical clinical scenarios. The signal generation and detection processes were simulated in order to determine the signal-to-noise limits. Methods: An analytical model was used to calculate the dose distribution and local pressure rise (per proton) for beams of different energy (100 and 160 MeV) and spot widths (1, 5, and 10 mm) in a water phantom. In this method, the acoustic waves propagating from the Bragg peak were generated by the general 3D pressure wave equation implemented using a finite element method. Various beam pulse widths (0.1–10 μs) were simulated by convolving the acoustic waves with Gaussian kernels. A realistic PZT ultrasound transducer (5 cm diameter) was simulated with a Butterworth bandpass filter with consideration of random noise based on a model of thermal noise in the transducer. The signal-to-noise ratio on a per-proton basis was calculated, determining the minimum number of protons required to generate a detectable pulse. The maximum spatial resolution of the proton-acoustic imaging modality was also estimated from the signal spectrum. Results: The calculated noise in the transducer was 12–28 mPa, depending on the transducer central frequency (70–380 kHz). The minimum number of protons detectable by the technique was on the order of 3–30 × 10 6 per pulse, with 30–800 mGy dose per pulse at the Bragg peak. Wider pulses produced signal with lower acoustic frequencies, with 10 μs pulses producing signals with frequency less than 100 kHz. Conclusions: The proton-acoustic process was simulated using a realistic model and the minimal detection limit was established for proton-acoustic range validation. These limits correspond to a best case scenario with a single large detector with no losses and detector thermal noise as the sensitivity limiting factor. Our study indicated practical proton-acoustic range

  9. Theoretical detection threshold of the proton-acoustic range verification technique

    Energy Technology Data Exchange (ETDEWEB)

    Ahmad, Moiz; Yousefi, Siavash; Xing, Lei, E-mail: lei@stanford.edu [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305-5847 (United States); Xiang, Liangzhong [Center for Bioengineering and School of Electrical and Computer Engineering, University of Oklahoma, Norman, Oklahoma 73019-1101 (United States)

    2015-10-15

    Purpose: Range verification in proton therapy using the proton-acoustic signal induced in the Bragg peak was investigated for typical clinical scenarios. The signal generation and detection processes were simulated in order to determine the signal-to-noise limits. Methods: An analytical model was used to calculate the dose distribution and local pressure rise (per proton) for beams of different energy (100 and 160 MeV) and spot widths (1, 5, and 10 mm) in a water phantom. In this method, the acoustic waves propagating from the Bragg peak were generated by the general 3D pressure wave equation implemented using a finite element method. Various beam pulse widths (0.1–10 μs) were simulated by convolving the acoustic waves with Gaussian kernels. A realistic PZT ultrasound transducer (5 cm diameter) was simulated with a Butterworth bandpass filter with consideration of random noise based on a model of thermal noise in the transducer. The signal-to-noise ratio on a per-proton basis was calculated, determining the minimum number of protons required to generate a detectable pulse. The maximum spatial resolution of the proton-acoustic imaging modality was also estimated from the signal spectrum. Results: The calculated noise in the transducer was 12–28 mPa, depending on the transducer central frequency (70–380 kHz). The minimum number of protons detectable by the technique was on the order of 3–30 × 10{sup 6} per pulse, with 30–800 mGy dose per pulse at the Bragg peak. Wider pulses produced signal with lower acoustic frequencies, with 10 μs pulses producing signals with frequency less than 100 kHz. Conclusions: The proton-acoustic process was simulated using a realistic model and the minimal detection limit was established for proton-acoustic range validation. These limits correspond to a best case scenario with a single large detector with no losses and detector thermal noise as the sensitivity limiting factor. Our study indicated practical proton

  10. Thermal ionization mass spectrometry (TIMS) of actinides: Pushing the limits of accuracy and detection

    Energy Technology Data Exchange (ETDEWEB)

    Buerger, Stefan; Boulyga, Sergei; Cunningham, Alan; Klose, Dilani; Koepf, Andreas; Poths, Jane [Safeguards Analytical Laboratory, International Atomic Energy Agency, Vienna (Austria); Richter, Stephan [Institute for Reference Materials and Measurements, JRC-EU, Geel (Belgium)

    2010-07-01

    New method developments in multi-collector thermal ionization mass spectrometry (MC-TIMS) for actinide isotope ratio analysis to improve accuracy and limits of detection will be presented. With respect to limits of detection, results on improving work function using various carbon additives will be reviewed and presented as well as developments in cavity ion source (as compared to standard flat ribbon filament ion source) for femto- and attogram levels of uranium, plutonium, and americium. With respect to accuracy, results on isotope ratio measurements of isotopes of uranium (relative accuracy of 0.3% to 0.01%) are presented with an example being U-234-Th-230 age-dating (NBL CRM 112-A). In this context, the importance of traceability (to the S.I. units) and the use of (certified) reference materials are emphasized. The focus of this presentation is on applications to nuclear safeguards / forensics.

  11. Flexible Modeling of Survival Data with Covariates Subject to Detection Limits via Multiple Imputation.

    Science.gov (United States)

    Bernhardt, Paul W; Wang, Huixia Judy; Zhang, Daowen

    2014-01-01

    Models for survival data generally assume that covariates are fully observed. However, in medical studies it is not uncommon for biomarkers to be censored at known detection limits. A computationally-efficient multiple imputation procedure for modeling survival data with covariates subject to detection limits is proposed. This procedure is developed in the context of an accelerated failure time model with a flexible seminonparametric error distribution. The consistency and asymptotic normality of the multiple imputation estimator are established and a consistent variance estimator is provided. An iterative version of the proposed multiple imputation algorithm that approximates the EM algorithm for maximum likelihood is also suggested. Simulation studies demonstrate that the proposed multiple imputation methods work well while alternative methods lead to estimates that are either biased or more variable. The proposed methods are applied to analyze the dataset from a recently-conducted GenIMS study.

  12. Evaluation on the detection limit of blood hemoglobin using photolepthysmography based on path-length optimization

    Science.gov (United States)

    Sun, Di; Guo, Chao; Zhang, Ziyang; Han, Tongshuai; Liu, Jin

    2016-10-01

    The blood hemoglobin concentration's (BHC) measurement using Photoplethysmography (PPG), which gets blood absorption to near infrared light from the instantaneous pulse of transmitted light intensity, has not been applied to the clinical use due to the non-enough precision. The main challenge might be caused of the non-enough stable pulse signal when it's very weak and it often varies in different human bodies or in the same body with different physiological states. We evaluated the detection limit of BHC using PPG as the measurement precision level, which can be considered as a best precision result because we got the relative stable subject's pulse signals recorded by using a spectrometer with high signal-to-noise ratio (SNR) level, which is about 30000:1 in short term. Moreover, we optimized the used pathlength using the theory based on optimum pathlength to get a better sensitivity to the absorption variation in blood. The best detection limit was evaluated as about 1 g/L for BHC, and the best SNR of pulse for in vivo measurement was about 2000:1 at 1130 and 1250 nm. Meanwhile, we conclude that the SNR of pulse signal should be better than 400:1 when the required detection limit is set to 5 g/L. Our result would be a good reference to the BHC measurement to get a desired BHC measurement precision of real application.

  13. Limits on surface gravities of Kepler planet-candidate host stars from non-detection of solar-like oscillations

    Energy Technology Data Exchange (ETDEWEB)

    Campante, T. L.; Chaplin, W. J.; Handberg, R.; Miglio, A.; Davies, G. R.; Elsworth, Y. P. [School of Physics and Astronomy, University of Birmingham, Edgbaston, Birmingham B15 2TT (United Kingdom); Lund, M. N.; Arentoft, T.; Christensen-Dalsgaard, J.; Karoff, C.; Kjeldsen, H.; Lundkvist, M. [Stellar Astrophysics Centre (SAC), Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, DK-8000 Aarhus C (Denmark); Huber, D. [NASA Ames Research Center, MS 244-30, Moffett Field, CA 94035 (United States); Hekker, S. [Astronomical Institute, " Anton Pannekoek," University of Amsterdam, Amsterdam (Netherlands); García, R. A. [Laboratoire AIM, CEA/DSM-CNRS-Université Paris Diderot (France); IRFU/SAp, Centre de Saclay, F-91191 Gif-sur-Yvette Cedex (France); Corsaro, E. [Instituut voor Sterrenkunde, KU Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Basu, S. [Department of Astronomy, Yale University, New Haven, CT 06520 (United States); Bedding, T. R. [Sydney Institute for Astronomy, School of Physics, University of Sydney, Sydney (Australia); Gilliland, R. L. [Center for Exoplanets and Habitable Worlds, The Pennsylvania State University, University Park, PA 16802 (United States); Kawaler, S. D., E-mail: campante@bison.ph.bham.ac.uk [Department of Physics and Astronomy, Iowa State University, Ames, IA 50011 (United States); and others

    2014-03-10

    We present a novel method for estimating lower-limit surface gravities (log g) of Kepler targets whose data do not allow the detection of solar-like oscillations. The method is tested using an ensemble of solar-type stars observed in the context of the Kepler Asteroseismic Science Consortium. We then proceed to estimate lower-limit log g for a cohort of Kepler solar-type planet-candidate host stars with no detected oscillations. Limits on fundamental stellar properties, as provided by this work, are likely to be useful in the characterization of the corresponding candidate planetary systems. Furthermore, an important byproduct of the current work is the confirmation that amplitudes of solar-like oscillations are suppressed in stars with increased levels of surface magnetic activity.

  14. Detection Limits for Nanoscale Biosensors

    National Research Council Canada - National Science Library

    Sheehan, Paul E; Whitman, Lloyd J

    2005-01-01

    We examine through analytical calculations and finite element simulations how the detection efficiency of disk and wire-like biosensors in unmixed fluids varies with size from the micrometer to nanometer scales...

  15. MINIMUM REQUIREMENTS FOR DETECTING A STOCHASTIC GRAVITATIONAL WAVE BACKGROUND USING PULSARS

    International Nuclear Information System (INIS)

    Cordes, J. M.; Shannon, R. M.

    2012-01-01

    We assess the detectability of a nanohertz gravitational wave (GW) background in a pulsar timing array (PTA) program by considering the shape and amplitude of the cross-correlation function summed over pulsar pairs. The distribution of correlation amplitudes is found to be non-Gaussian and highly skewed, which significantly influences detection and false-alarm probabilities. When only white noise combines with GWs in timing data, our detection results are consistent with those found by others. Contamination by red noise from spin variations and from any uncorrected interstellar plasma effects significantly increases the false-alarm probability. The number of arrival times (and thus the observing cadence) is important only as long as the residuals are dominated by white noise. When red noise and GWs dominate, the statistical significance of the correlation estimate can be improved only by increasing the number of pulsars. We characterize plausible detection regimes by evaluating the number of millisecond pulsars (MSPs) that must be monitored in a high-cadence, five-year timing program to detect a GW background spectrum h c (f) = A(f/f 0 ) –2/3 with f 0 = 1 yr –1 and A = 10 –15 . Our results indicate that a sample of 20 super-stable MSPs—those with rms timing residuals σ r ∼ –15 ) from red-noise contributions over a five-year span—will allow detection of the GW background and study of its spectrum. However, a timing program on ∼> 50-100 MSPs is likely needed for a complete PTA program, particularly if red noise is generally present in MSPs.

  16. Picomolar detection limits with current-polarized Pb2+ ion-selective membranes.

    Science.gov (United States)

    Pergel, E; Gyurcsányi, R E; Tóth, K; Lindner, E

    2001-09-01

    Minor ion fluxes across ion-selective membranes bias submicromolar activity measurements with conventional ion-selective electrodes. When ion fluxes are balanced, the lower limit of detection is expected to be dramatically improved. As proof of principle, the flux of lead ions across an ETH 5435 ionophore-based lead-selective membrane was gradually compensated by applying a few nanoamperes of galvanostatic current. When the opposite ion fluxes were matched, and the undesirable leaching of primary ions was eliminated, Nernstian response down to 3 x 10(-12) M was achieved.

  17. Minimum income protection in the Netherlands

    NARCIS (Netherlands)

    van Peijpe, T.

    2009-01-01

    This article offers an overview of the Dutch legal system of minimum income protection through collective bargaining, social security, and statutory minimum wages. In addition to collective agreements, the Dutch statutory minimum wage offers income protection to a small number of workers. Its

  18. 50 CFR 640.21 - Harvest limitations.

    Science.gov (United States)

    2010-10-01

    ... § 640.21 Harvest limitations. (a) Berried lobsters. A berried (egg-bearing) spiny lobster or slipper...) Undersized attractants. A live spiny lobster under the minimum size limit specified in paragraph (b)(1) of... future use as an attractant in a trap provided it is held in a live well aboard the vessel. No more than...

  19. High-Field Quench Behavior and Protection of $Bi_2 Sr_2 Ca Cu_2 O_x$ Coils: Minimum and Maximum Quench Detection Voltages

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Tengming [Fermilab; Ye, Liyang [NCSU, Raleigh; Turrioni, Daniele [Fermilab; Li, Pei [Fermilab

    2015-01-01

    Small insert coils have been built using a multifilamentary Bi2Sr2CaCu2Ox round wire, and characterized in background fields to explore the quench behaviors and limits of Bi2Sr2CaCu2Ox superconducting magnets, with an emphasis on assessing the impact of slow normal zone propagation on quench detection. Using heaters of various lengths to initiate a small normal zone, a coil was quenched safely more than 70 times without degradation, with the maximum coil temperature reaching 280 K. Coils withstood a resistive voltage of tens of mV for seconds without quenching, showing the high stability of these coils and suggesting that the quench detection voltage shall be greater than 50 mV to not to falsely trigger protection. The hot spot temperature for the resistive voltage of the normal zone to reach 100 mV increases from ~40 K to ~80 K with increasing the operating wire current density Jo from 89 A/mm2 to 354 A/mm2 whereas for the voltage to reach 1 V, it increases from ~60 K to ~140 K, showing the increasing negative impact of slow normal zone propagation on quench detection with increasing Jo and the need to limit the quench detection voltage to < 1 V. These measurements, coupled with an analytical quench model, were used to access the impact of the maximum allowable voltage and temperature upon quench detection on the quench protection, assuming to limit the hot spot temperature to <300 K.

  20. Minimum deterrence and regional security. Section 2. Other regions

    International Nuclear Information System (INIS)

    Azikiwe, A.E.

    1993-01-01

    Compared to European political and security circumstance, minimum deterrence is less an illusion in other regions where weapon free zones already exist. It will continue to be relevant to the security of other regions. Strategic arms limitation should be pursued vigorously in a constructive and pragmatic manner, bearing in mind the need to readjust to new global challenges. The Comprehensive Test Ban Treaty is the linchpin on which the Non-proliferation Treaty rests

  1. Extension of Gutenberg-Richter distribution to MW -1.3, no lower limit in sight

    Science.gov (United States)

    Boettcher, Margaret S.; McGarr, A.; Johnston, Malcolm

    2009-05-01

    With twelve years of seismic data from TauTona Gold Mine, South Africa, we show that mining-induced earthquakes follow the Gutenberg-Richter relation with no scale break down to the completeness level of the catalog, at moment magnitude M W -1.3. Events recorded during relatively quiet hours in 2006 indicate that catalog detection limitations, not earthquake source physics, controlled the previously reported minimum magnitude in this mine. Within the Natural Earthquake Laboratory in South African Mines (NELSAM) experiment's dense seismic array, earthquakes that exhibit shear failure at magnitudes as small as M W -3.9 are observed, but we find no evidence that M W -3.9 represents the minimum magnitude. In contrast to previous work, our results imply small nucleation zones and that earthquake processes in the mine can readily be scaled to those in either laboratory experiments or natural faults.

  2. The study on the lidar's detection limit for Iodine Gas

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Dong-lyul; Baik, Seung-Hoon; Park, Seung-Kyu; Park, Nak-Gyu; Ahn, Yong-Jin [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    A powerful and reliable tool for range-resolved remote sensing of gas concentrations that has proven its capabilities in a variety of studies is the differential absorption lidar (DIAL). Differential absorption lidar (DIAL) is frequently used for atmospheric gas monitoring to detect impurities such as nitrogen dioxide, sulfur dioxide, iodine, and ozone. DIAL can measure air pollutant concentrations with a high spatial resolution by adopting two laser systems with different degrees of absorption between the two different wavelengths. The absorption of the reference wavelength is very weak, while the absorption of the other wavelength is very strong. In this paper, we measured the limit of detection capability of our designed DIAL system. The DIAL measurements were performed using a target iodine cell in the laboratory. We confirmed that the concentration of iodine gas ratio increased after the laser passed through the iodine cell. The system of DIAL(Differential Absorption Lidar) was effective to detect the iodine gas. We obtained the signals from the iodine target cell and the lidar signal from the iodine target cell was proportional to frequency locking ratios.

  3. First direct detection limits on sub-GeV dark matter from XENON10.

    Science.gov (United States)

    Essig, Rouven; Manalaysay, Aaron; Mardon, Jeremy; Sorensen, Peter; Volansky, Tomer

    2012-07-13

    The first direct detection limits on dark matter in the MeV to GeV mass range are presented, using XENON10 data. Such light dark matter can scatter with electrons, causing ionization of atoms in a detector target material and leading to single- or few-electron events. We use 15  kg day of data acquired in 2006 to set limits on the dark-matter-electron scattering cross section. The strongest bound is obtained at 100 MeV where σ(e)dark-matter masses between 20 MeV and 1 GeV are bounded by σ(e)dark-matter candidates with masses well below the GeV scale.

  4. Evaluation of the minimum iodine concentration for contrast-enhanced subtraction mammography

    International Nuclear Information System (INIS)

    Baldelli, P; Bravin, A; Maggio, C Di; Gennaro, G; Sarnelli, A; Taibi, A; Gambaccini, M

    2006-01-01

    Early manifestation of breast cancer is often very subtle and is displayed in a complex and variable pattern of normal anatomy that may obscure the disease. The use of dual-energy techniques, that can remove the structural noise, and contrast media, that enhance the region surrounding the tumour, could help us to improve the detectability of the lesions. The aim of this work is to investigate the use of an iodine-based contrast medium in mammography with two different double exposure techniques: K-edge subtraction mammography and temporal subtraction mammography. Both techniques have been investigated by using an ideal source, like monochromatic beams produced at a synchrotron radiation facility and a clinical digital mammography system. A dedicated three-component phantom containing cavities filled with different iodine concentrations has been developed and used for measurements. For each technique, information about the minimum iodine concentration, which provides a significant enhancement of the detectability of the pathology by minimizing the risk due to high dose and high concentration of contrast medium, has been obtained. In particular, for cavities of 5 and 8 mm in diameter filled with iodine solutions, the minimum concentration needed to obtain a contrast-to-noise ratio of 5 with a mean glandular dose of 2 mGy has been calculated. The minimum concentrations estimated with monochromatic beams and K-edge subtraction mammography are 0.9 mg ml -1 and 1.34 mg ml -1 for the biggest and smallest details, respectively, while for temporal subtraction mammography they are 0.84 mg ml -1 and 1.31 mg ml -1 . With the conventional clinical system the minimum concentrations for the K-edge subtraction mammography are 4.13 mg ml -1 (8 mm diameter) and 5.75 mg ml -1 (5 mm diameter), while for the temporal subtraction mammography they are 1.01 mg ml -1 (8 mm diameter) and 1.57 mg ml -1 (5 mm diameter)

  5. Improved superficial brain hemorrhage visualization in susceptibility weighted images by constrained minimum intensity projection

    Science.gov (United States)

    Castro, Marcelo A.; Pham, Dzung L.; Butman, John

    2016-03-01

    Minimum intensity projection is a technique commonly used to display magnetic resonance susceptibility weighted images, allowing the observer to better visualize hemorrhages and vasculature. The technique displays the minimum intensity in a given projection within a thick slab, allowing different connectivity patterns to be easily revealed. Unfortunately, the low signal intensity of the skull within the thick slab can mask superficial tissues near the skull base and other regions. Because superficial microhemorrhages are a common feature of traumatic brain injury, this effect limits the ability to proper diagnose and follow up patients. In order to overcome this limitation, we developed a method to allow minimum intensity projection to properly display superficial tissues adjacent to the skull. Our approach is based on two brain masks, the largest of which includes extracerebral voxels. The analysis of the rind within both masks containing the actual brain boundary allows reclassification of those voxels initially missed in the smaller mask. Morphological operations are applied to guarantee accuracy and topological correctness, and the mean intensity within the mask is assigned to all outer voxels. This prevents bone from dominating superficial regions in the projection, enabling superior visualization of cortical hemorrhages and vessels.

  6. The ground fault detection system for the Tore Supra toroidal pump limiter

    International Nuclear Information System (INIS)

    Zunino, K.; Cara, P.; Fejoz, P.; Hourtoule, J.; Loarer, T.; Pomaro, N.; Santagiustina, A.; Spuig, P.; Villecroze, F.

    2003-01-01

    The toroidal pump limiter (TPL) of Tore Supra is electrically insulated from the vacuum-vessel, to allow its polarization at a voltage of up to 1 kV. In order to monitor continuously the integrity of the TPL electrical insulation, an electronic diagnostic system called TPL ground fault detection system (GFDS) has been developed. The paper will report on the design and the operation experience of the GFD system and on the evolution of the TPL grounding

  7. A comparison of minimum dietary diversity in Bangladesh in 2011 and 2014.

    Science.gov (United States)

    Blackstone, Sarah; Sanghvi, Tina

    2018-04-16

    Improving infant and young child feeding practices is critical for improving growth and reducing child mortality and morbidity. This paper aims to compare predictors of minimum dietary diversity, an important indicator of adequate complementary feeding practices, in Bangladesh in 2011 and 2014. The 2011 and 2014 Bangladesh Demographic and Health Survey were used to examine predictors of minimum dietary diversity among 6-23 months. An additional analysis was conducted for the 18-23-month group, because a significant increase in meeting minimum dietary diversity recommendations was seen in this age group only. Factors found to be associated with practices were compared across time points. In 2011, minimum dietary diversity was 23.8% and increased to 28.8% in 2014. Among children 18-23 months, in 2011, minimum dietary diversity was 32.5% and increased to 42.8% in 2014. Among all children, wealth, education, exposure to media, and antenatal care were significant predictors of dietary diversity. In the 18-23-month age group, significant predictors in 2011 were wealth and decision making. In 2014, significant predictors were education and exposure to media. Demographic trends indicated a significant increase in education and exposure to media between 2011 and 2014. As these were significant for minimum dietary diversity in 2014 overall and for 18-23 months, they might be important targets of future interventions, specifically utilizing media channels and tailoring special strategies for women with low education and limited exposure to media. © 2018 John Wiley & Sons Ltd.

  8. Detection capabilities and accuracy requirements of concentrations of radioactive material in air for radiation protection purposes

    International Nuclear Information System (INIS)

    Brodsky, A.

    1987-01-01

    Recent developments in the formulation of detection capability and accuracy criteria for bioassay measurements will be interpreted and adapted to provide similar criteria for the measurement of air concentrations of radioactive material for radiation protection purposes. Considerations of accuracy will be related to the known variability of measurement processes, as well as the uncertainties in the calculated limits of intake that serve as the basis of regulatory and voluntary standards of practice. Formulations and criteria will be presented for minimum detection amounts (MDA) and precision and bias of measurements for radiation protection purposes. 17 references

  9. [Storage of plant protection products in farms: minimum safety requirements].

    Science.gov (United States)

    Dutto, Moreno; Alfonzo, Santo; Rubbiani, Maristella

    2012-01-01

    Failure to comply with requirements for proper storage and use of pesticides in farms can be extremely hazardous and the risk of accidents involving farm workers, other persons and even animals is high. There are still wide differences in the interpretation of the concept of "securing or making safe", by workers in this sector. One of the critical points detected, particularly in the fruit sector, is the establishment of an adequate storage site for plant protection products. The definition of "safe storage of pesticides" is still unclear despite the recent enactment of Legislative Decree 81/2008 regulating health and work safety in Italy. In addition, there are no national guidelines setting clear minimum criteria for storage of plant protection products in farms. The authors, on the basis of their professional experience and through analysis of recent legislation, establish certain minimum safety standards for storage of pesticides in farms.

  10. The Need for Higher Minimum Staffing Standards in U.S. Nursing Homes

    Science.gov (United States)

    Harrington, Charlene; Schnelle, John F.; McGregor, Margaret; Simmons, Sandra F.

    2016-01-01

    Many U.S. nursing homes have serious quality problems, in part, because of inadequate levels of nurse staffing. This commentary focuses on two issues. First, there is a need for higher minimum nurse staffing standards for U.S. nursing homes based on multiple research studies showing a positive relationship between nursing home quality and staffing and the benefits of implementing higher minimum staffing standards. Studies have identified the minimum staffing levels necessary to provide care consistent with the federal regulations, but many U.S. facilities have dangerously low staffing. Second, the barriers to staffing reform are discussed. These include economic concerns about costs and a focus on financial incentives. The enforcement of existing staffing standards has been weak, and strong nursing home industry political opposition has limited efforts to establish higher standards. Researchers should study the ways to improve staffing standards and new payment, regulatory, and political strategies to improve nursing home staffing and quality. PMID:27103819

  11. The impact of the UK National Minimum Wage on mental health

    Directory of Open Access Journals (Sweden)

    Christoph Kronenberg

    2017-12-01

    Full Text Available Despite an emerging literature, there is still sparse and mixed evidence on the wider societal benefits of Minimum Wage policies, including their effects on mental health. Furthermore, causal evidence on the relationship between earnings and mental health is limited. We focus on low-wage earners, who are at higher risk of psychological distress, and exploit the quasi-experiment provided by the introduction of the UK National Minimum Wage (NMW to identify the causal impact of wage increases on mental health. We employ difference-in-differences models and find that the introduction of the UK NMW had no effect on mental health. Our estimates do not appear to support earlier findings which indicate that minimum wages affect mental health of low-wage earners. A series of robustness checks accounting for measurement error, as well as treatment and control group composition, confirm our main results. Overall, our findings suggest that policies aimed at improving the mental health of low-wage earners should either consider the non-wage characteristics of employment or potentially larger wage increases.

  12. The impact of the UK National Minimum Wage on mental health.

    Science.gov (United States)

    Kronenberg, Christoph; Jacobs, Rowena; Zucchelli, Eugenio

    2017-12-01

    Despite an emerging literature, there is still sparse and mixed evidence on the wider societal benefits of Minimum Wage policies, including their effects on mental health. Furthermore, causal evidence on the relationship between earnings and mental health is limited. We focus on low-wage earners, who are at higher risk of psychological distress, and exploit the quasi-experiment provided by the introduction of the UK National Minimum Wage (NMW) to identify the causal impact of wage increases on mental health. We employ difference-in-differences models and find that the introduction of the UK NMW had no effect on mental health. Our estimates do not appear to support earlier findings which indicate that minimum wages affect mental health of low-wage earners. A series of robustness checks accounting for measurement error, as well as treatment and control group composition, confirm our main results. Overall, our findings suggest that policies aimed at improving the mental health of low-wage earners should either consider the non-wage characteristics of employment or potentially larger wage increases.

  13. Implications of Liebig’s law of the minimum for tree-ring reconstructions of climate

    Science.gov (United States)

    Stine, A. R.; Huybers, P.

    2017-11-01

    A basic principle of ecology, known as Liebig’s Law of the Minimum, is that plant growth reflects the strongest limiting environmental factor. This principle implies that a limiting environmental factor can be inferred from historical growth and, in dendrochronology, such reconstruction is generally achieved by averaging collections of standardized tree-ring records. Averaging is optimal if growth reflects a single limiting factor and noise but not if growth also reflects locally variable stresses that intermittently limit growth. In this study a collection of Arctic tree ring records is shown to follow scaling relationships that are inconsistent with the signal-plus-noise model of tree growth but consistent with Liebig’s Law acting at the local level. Also consistent with law-of-the-minimum behavior is that reconstructions based on the least-stressed trees in a given year better-follow variations in temperature than typical approaches where all tree-ring records are averaged. Improvements in reconstruction skill occur across all frequencies, with the greatest increase at the lowest frequencies. More comprehensive statistical-ecological models of tree growth may offer further improvement in reconstruction skill.

  14. Physiological techniques for detecting expiratory flow limitation during tidal breathing

    Directory of Open Access Journals (Sweden)

    N.G. Koulouris

    2011-09-01

    Full Text Available Patients with severe chronic obstructive pulmonary disease (COPD often exhale along the same flow–volume curve during quiet breathing as they do during the forced expiratory vital capacity manoeuvre, and this has been taken as an indicator of expiratory flow limitation at rest (EFLT. Therefore, EFLT, namely attainment of maximal expiratory flow during tidal expiration, occurs when an increase in transpulmonary pressure causes no increase in expiratory flow. EFLT leads to small airway injury and promotes dynamic pulmonary hyperinflation, with concurrent dyspnoea and exercise limitation. In fact, EFLT occurs commonly in COPD patients (mainly in Global Initiative for Chronic Obstructive Lung Disease III and IV stage, in whom the latter symptoms are common, but is not exclusive to COPD, since it can also be detected in other pulmonary and nonpulmonary diseases like asthma, acute respiratory distress syndrome, heart failure and obesity, etc. The existing up to date physiological techniques of assessing EFLT are reviewed in the present work. Among the currently available techniques, the negative expiratory pressure has been validated in a wide variety of settings and disorders. Consequently, it should be regarded as a simple, noninvasive, practical and accurate new technique.

  15. Understanding the Minimum Wage: Issues and Answers.

    Science.gov (United States)

    Employment Policies Inst. Foundation, Washington, DC.

    This booklet, which is designed to clarify facts regarding the minimum wage's impact on marketplace economics, contains a total of 31 questions and answers pertaining to the following topics: relationship between minimum wages and poverty; impacts of changes in the minimum wage on welfare reform; and possible effects of changes in the minimum wage…

  16. Youth minimum wages and youth employment

    NARCIS (Netherlands)

    Marimpi, Maria; Koning, Pierre

    2018-01-01

    This paper performs a cross-country level analysis on the impact of the level of specific youth minimum wages on the labor market performance of young individuals. We use information on the use and level of youth minimum wages, as compared to the level of adult minimum wages as well as to the median

  17. Diamond-based electrochemical aptasensor realizing a femtomolar detection limit of bisphenol A.

    Science.gov (United States)

    Ma, Yibo; Liu, Junsong; Li, Hongdong

    2017-06-15

    In this study, we designed and fabricated an electrochemical impedance aptasensor based on Au nanoparticles (Au-NPs) coated boron-doped diamond (BDD) modified with aptamers, and 6-mercapto-1-hexanol (MCH) for the detection of bisphenol A (BPA). The constructed BPA aptasensor exhibits good linearity from 1.0×10 -14 to 1.0×10 -9 molL -1 . The detection limitation of 7.2×10 -15 molL -1 was achieved, which can be attributed to the synergistic effect of combining BDD with Au-NPs, aptamers, and MCH. The examine results of BPA traces in Tris-HCl buffer and in milk, UV spectra of aptamer/BPA and interference test revealed that the novel aptasensors are of high sensitivity, specificity, stability and repeatability, which could be promising in practical applications. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Discretization of space and time: determining the values of minimum length and minimum time

    OpenAIRE

    Roatta , Luca

    2017-01-01

    Assuming that space and time can only have discrete values, we obtain the expression of the minimum length and the minimum time interval. These values are found to be exactly coincident with the Planck's length and the Planck's time but for the presence of h instead of ħ .

  19. Minimum wage development in the Russian Federation

    OpenAIRE

    Bolsheva, Anna

    2012-01-01

    The aim of this paper is to analyze the effectiveness of the minimum wage policy at the national level in Russia and its impact on living standards in the country. The analysis showed that the national minimum wage in Russia does not serve its original purpose of protecting the lowest wage earners and has no substantial effect on poverty reduction. The national subsistence minimum is too low and cannot be considered an adequate criterion for the setting of the minimum wage. The minimum wage d...

  20. Improved sensitivity and limit-of-detection of lateral flow devices using spatial constrictions of the flow-path.

    Science.gov (United States)

    Katis, Ioannis N; He, Peijun J W; Eason, Robert W; Sones, Collin L

    2018-05-03

    We report on the use of a laser-direct write (LDW) technique that allows the fabrication of lateral flow devices with enhanced sensitivity and limit of detection. This manufacturing technique comprises the dispensing of a liquid photopolymer at specific regions of a nitrocellulose membrane and its subsequent photopolymerisation to create impermeable walls inside the volume of the membrane. These polymerised structures are intentionally designed to create fluidic channels which are constricted over a specific length that spans the test zone within which the sample interacts with pre-deposited reagents. Experiments were conducted to show how these constrictions alter the fluid flow rate and the test zone area within the constricted channel geometries. The slower flow rate and smaller test zone area result in the increased sensitivity and lowered limit of detection for these devices. We have quantified these via the improved performance of a C-Reactive Protein (CRP) sandwich assay on our lateral flow devices with constricted flow paths which demonstrate an improvement in its sensitivity by 62x and in its limit of detection by 30x when compared to a standard lateral flow CRP device. Crown Copyright © 2018. Published by Elsevier B.V. All rights reserved.

  1. Limit of detection for the determination of Pt in biological material by RNAA using electrolytic separation of gold

    International Nuclear Information System (INIS)

    Xilei, L.; Heydorn, K.; Rietz, B.

    1992-01-01

    Neutron activation analysis based on the 199 Au indicator for platinum requires the separation of gold at high radiochemical purity. The limit of detection is strongly affected by the presence of gold; with a gold content of 50 pg/g, irradiating for 5 days at 5*10 13 n/cm 2 is needed to achieve a limit of detection of approximately 30 pg/g. In this case the nuclear interference from gold will exceeded the level of platium by several orders of magnitude and has to be determined with exceedingly high precision. Preliminary results for SRM 1577 Bovine Liver with 95% yield gave consistent results for Au, but Pt could not be detected. (author) 23 refs.; 3 figs.; 4 tabs

  2. Efficient alpha particle detection by CR-39 applying 50 Hz-HV electrochemical etching method

    International Nuclear Information System (INIS)

    Sohrabi, M.; Soltani, Z.

    2016-01-01

    Alpha particles can be detected by CR-39 by applying either chemical etching (CE), electrochemical etching (ECE), or combined pre-etching and ECE usually through a multi-step HF-HV ECE process at temperatures much higher than room temperature. By applying pre-etching, characteristics responses of fast-neutron-induced recoil tracks in CR-39 by HF-HV ECE versus KOH normality (N) have shown two high-sensitivity peaks around 5–6 and 15–16 N and a large-diameter peak with a minimum sensitivity around 10–11 N at 25°C. On the other hand, 50 Hz-HV ECE method recently advanced in our laboratory detects alpha particles with high efficiency and broad registration energy range with small ECE tracks in polycarbonate (PC) detectors. By taking advantage of the CR-39 sensitivity to alpha particles, efficacy of 50 Hz-HV ECE method and CR-39 exotic responses under different KOH normalities, detection characteristics of 0.8 MeV alpha particle tracks were studied in 500 μm CR-39 for different fluences, ECE duration and KOH normality. Alpha registration efficiency increased as ECE duration increased to 90 ± 2% after 6–8 h beyond which plateaus are reached. Alpha track density versus fluence is linear up to 10 6  tracks cm −2 . The efficiency and mean track diameter versus alpha fluence up to 10 6  alphas cm −2 decrease as the fluence increases. Background track density and minimum detection limit are linear functions of ECE duration and increase as normality increases. The CR-39 processed for the first time in this study by 50 Hz-HV ECE method proved to provide a simple, efficient and practical alpha detection method at room temperature. - Highlights: • Alpha particles of 0.8 MeV were detected in CR-39 by 50 Hz-HV ECE method. • Efficiency/track diameter was studied vs fluence and time for 3 KOH normality. • Background track density and minimum detection limit vs duration were studied. • A new simple, efficient and low-cost alpha detection method

  3. Detection limits of pollutants in water for PGNAA using Am-Be source

    International Nuclear Information System (INIS)

    Khelifi, R.; Amokrane, A.; Bode, P.

    2007-01-01

    A basic PGNAA facility with an Am-Be neutron source is described to analyze the pollutants in water. The properties of neutron flux were determined by MCNP calculations. In order to determine the efficiency curve of a HPGe detector, the prompt-gamma rays from chlorine were used and an exponential curve was fitted. The detection limits for typical water sample are also estimated using the statistical fluctuations of the background level in the areas of recorded the prompt-gamma spectrum

  4. Minimum emittance of three-bend achromats

    International Nuclear Information System (INIS)

    Li Xiaoyu; Xu Gang

    2012-01-01

    The calculation of the minimum emittance of three-bend achromats (TBAs) made by Mathematical software can ignore the actual magnets lattice in the matching condition of dispersion function in phase space. The minimum scaling factors of two kinds of widely used TBA lattices are obtained. Then the relationship between the lengths and the radii of the three dipoles in TBA is obtained and so is the minimum scaling factor, when the TBA lattice achieves its minimum emittance. The procedure of analysis and the results can be widely used in achromats lattices, because the calculation is not restricted by the actual lattice. (authors)

  5. Direct Detection Electron Energy-Loss Spectroscopy: A Method to Push the Limits of Resolution and Sensitivity.

    Science.gov (United States)

    Hart, James L; Lang, Andrew C; Leff, Asher C; Longo, Paolo; Trevor, Colin; Twesten, Ray D; Taheri, Mitra L

    2017-08-15

    In many cases, electron counting with direct detection sensors offers improved resolution, lower noise, and higher pixel density compared to conventional, indirect detection sensors for electron microscopy applications. Direct detection technology has previously been utilized, with great success, for imaging and diffraction, but potential advantages for spectroscopy remain unexplored. Here we compare the performance of a direct detection sensor operated in counting mode and an indirect detection sensor (scintillator/fiber-optic/CCD) for electron energy-loss spectroscopy. Clear improvements in measured detective quantum efficiency and combined energy resolution/energy field-of-view are offered by counting mode direct detection, showing promise for efficient spectrum imaging, low-dose mapping of beam-sensitive specimens, trace element analysis, and time-resolved spectroscopy. Despite the limited counting rate imposed by the readout electronics, we show that both core-loss and low-loss spectral acquisition are practical. These developments will benefit biologists, chemists, physicists, and materials scientists alike.

  6. 30 CFR 57.19021 - Minimum rope strength.

    Science.gov (United States)

    2010-07-01

    ... feet: Minimum Value=Static Load×(7.0−0.001L) For rope lengths 3,000 feet or greater: Minimum Value=Static Load×4.0. (b) Friction drum ropes. For rope lengths less than 4,000 feet: Minimum Value=Static Load×(7.0−0.0005L) For rope lengths 4,000 feet or greater: Minimum Value=Static Load×5.0. (c) Tail...

  7. 30 CFR 56.19021 - Minimum rope strength.

    Science.gov (United States)

    2010-07-01

    ... feet: Minimum Value=Static Load×(7.0-0.001L) For rope lengths 3,000 feet or greater: Minimum Value=Static Load×4.0 (b) Friction drum ropes. For rope lengths less than 4,000 feet: Minimum Value=Static Load×(7.0-0.0005L) For rope lengths 4,000 feet or greater: Minimum Value=Static Load×5.0 (c) Tail ropes...

  8. The power of reordering for online minimum makespan scheduling

    OpenAIRE

    Englert, Matthias; Özmen, Deniz; Westermann, Matthias

    2014-01-01

    In the classic minimum makespan scheduling problem, we are given an input sequence of jobs with processing times. A scheduling algorithm has to assign the jobs to m parallel machines. The objective is to minimize the makespan, which is the time it takes until all jobs are processed. In this paper, we consider online scheduling algorithms without preemption. However, we do not require that each arriving job has to be assigned immediately to one of the machines. A reordering buffer with limited...

  9. ROBUST ESTIMATION OF MEAN AND VARIANCE USING ENVIRONMENTAL DATA SETS WITH BELOW DETECTION LIMIT OBSERVATIONS

    Science.gov (United States)

    Scientists, especially environmental scientists often encounter trace level concentrations that are typically reported as less than a certain limit of detection, L. Type 1, left-censored data arise when certain low values lying below L are ignored or unknown as they cannot be mea...

  10. Method to Solve the Problem of the Radioactivity Detection in Environmental Samples. Characteristic Limits; Metodos para la Resolucion del Problema de la Detecfcion de Radiactividad en Muestras Ambientales. Limites Caracteristicos

    Energy Technology Data Exchange (ETDEWEB)

    Gasco, C.; Martinez, M.; Heras, M.

    2009-07-21

    The problem of the detection or when the radioactivity can be considered as higher than the background using different measurement techniques has been the objective of several statistical studies and controversies. The detection limit and the critical limit were studied by Currie in year 1968 and used by radiochemistry laboratories considering different ways of calculation that introduced confusion and not correct implementations. In the last few years, and due to the increasing number of standardization processes on the field of radioactivity and accreditation, several international institutions have chosen to unify the criteria for using common determination of detection limits. The most used methods are those developed by MARLAP and International Standard Organization ISO (Standard-11929). In this report are summarised both standards doing a comparative study and giving some examples of how to apply these limits. In same cases, little differences in the uncertainty calculation have been observed but the final results have been concordant. A deeply study of these standards can be done consulting the web page of the American Labs that developed MARLAP or buying the original ISO standard ISO-11929 recently approved (2009). (Author) 17 refs.

  11. 30 CFR 77.1431 - Minimum rope strength.

    Science.gov (United States)

    2010-07-01

    ... feet: Minimum Value=Static Load×(7.0−0.001L) For rope lengths 3,000 feet or greater: Minimum Value=Static Load×4.0 (b) Friction drum ropes. For rope lengths less than 4,000 feet: Minimum Value=Static Load×(7.0−0.0005L) For rope lengths 4,000 feet or greater: Minimum Value=Static Load×5.0 (c) Tail ropes...

  12. Detecting terrestrial nutrient limitation: a global meta-analysis of foliar nutrient concentrations after fertilization

    Directory of Open Access Journals (Sweden)

    Rebecca eOstertag

    2016-03-01

    Full Text Available Examining foliar nutrient concentrations after fertilization provides an alternative method for detecting nutrient limitation of ecosystems, which is logistically simpler to measure than biomass change. We present a meta-analysis of response ratios of foliar nitrogen and phosphorus (RRN, RRP after addition of fertilizer of nitrogen (N, phosphorus (P, or the two elements in combination, in relation to climate, ecosystem type, life form, family, and methodological factors. Results support other meta-analyses using biomass, and demonstrate there is strong evidence for nutrient limitation in natural communities. However, because N fertilization experiments greatly outnumber P fertilization trials, it is difficult to discern the absolute importance of N vs. P vs. co-limitation across ecosystems. Despite these caveats, it is striking that results did not follow conventional wisdom that temperate ecosystems are N-limited and tropical ones are P-limited. In addition, the use of ratios of N-to-P rather than response ratios also are a useful index of nutrient limitation, but due to large overlap in values, there are unlikely to be universal cutoff values for delimiting N vs. P limitation. Differences in RRN and RRP were most significant across ecosystem types, plant families, life forms, and between competitive environments, but not across climatic variables.

  13. A Phosphate Minimum in the Oxygen Minimum Zone (OMZ) off Peru

    Science.gov (United States)

    Paulmier, A.; Giraud, M.; Sudre, J.; Jonca, J.; Leon, V.; Moron, O.; Dewitte, B.; Lavik, G.; Grasse, P.; Frank, M.; Stramma, L.; Garcon, V.

    2016-02-01

    The Oxygen Minimum Zone (OMZ) off Peru is known to be associated with the advection of Equatorial SubSurface Waters (ESSW), rich in nutrients and poor in oxygen, through the Peru-Chile UnderCurrent (PCUC), but this circulation remains to be refined within the OMZ. During the Pelágico cruise in November-December 2010, measurements of phosphate revealed the presence of a phosphate minimum (Pmin) in various hydrographic stations, which could not be explained so far and could be associated with a specific water mass. This Pmin, localized at a relatively constant layer ( 20minimum with a mean vertical phosphate decrease of 0.6 µM but highly variable between 0.1 and 2.2 µM. In average, these Pmin are associated with a predominant mixing of SubTropical Under- and Surface Waters (STUW and STSW: 20 and 40%, respectively) within ESSW ( 25%), complemented evenly by overlying (ESW, TSW: 8%) and underlying waters (AAIW, SPDW: 7%). The hypotheses and mechanisms leading to the Pmin formation in the OMZ are further explored and discussed, considering the physical regional contribution associated with various circulation pathways ventilating the OMZ and the local biogeochemical contribution including the potential diazotrophic activity.

  14. Analysis of detection limit to time-resolved coherent anti-Stokes Raman scattering nanoscopy

    International Nuclear Information System (INIS)

    Liu Wei; Liu Shuang-Long; Chen Dan-Ni; Niu Han-Ben

    2014-01-01

    In the implementation of CARS nanoscopy, signal strength decreases with focal volume size decreasing. A crucial problem that remains to be solved is whether the reduced signal generated in the suppressed focal volume can be detected. Here reported is a theoretical analysis of detection limit (DL) to time-resolved CARS (T-CARS) nanoscopy based on our proposed additional probe-beam-induced phonon depletion (APIPD) method for the low concentration samples. In order to acquire a detailed shot-noise limited signal-to-noise (SNR) and the involved parameters to evaluate DL, the T-CARS process is described with full quantum theory to estimate the extreme power density levels of the pump and Stokes beams determined by saturation behavior of coherent phonons, which are both actually on the order of ∼ 10 9 W/cm 2 . When the pump and Stokes intensities reach such values and the total intensity of the excitation beams arrives at a maximum tolerable by most biological samples in a certain suppressed focal volume (40-nm suppressed focal scale in APIPD method), the DL correspondingly varies with exposure time, for example, DL values are 10 3 and 10 2 when exposure times are 20 ms and 200 ms respectively. (electromagnetism, optics, acoustics, heat transfer, classical mechanics, and fluid dynamics)

  15. New limits on the detection of a composition-dependent macroscopic force

    International Nuclear Information System (INIS)

    Boynton, P.; Aronson, S.

    1990-01-01

    We report here on a continuing experimental search for a macroscopic, composition dependent force coupling to ordinary matter. Within the phenomenological framework commonly employed -- a Yukawa representation of the interaction potential, and composition specified as some linear combination of baryon and lepton numbers -- the Index 3 experiment sets the most stringent upper limits yet on the interaction strength for coupling from B-2L to B-L, and for an interaction range from 200 m to 10 km. It is also the first null result to conflict with the marginal detection reported for the Index 1 experiment for all relevant values of the composition and range parameters

  16. First NuSTAR Limits on Quiet Sun Hard X-Ray Transient Events

    DEFF Research Database (Denmark)

    Marsh, Andrew J.; Smith, David M.; Glesener, Lindsay

    2017-01-01

    We present the first results of a search for transient hard X-ray (HXR) emission in the quiet solar corona with the Nuclear Spectroscopic Telescope Array (NuSTAR) satellite. While NuSTAR was designed as an astrophysics mission, it can observe the Sun above 2 keV with unprecedented sensitivity due...... to its pioneering use of focusing optics. NuSTAR first observed quiet-Sun regions on 2014 November 1, although out-of-view active regions contributed a notable amount of background in the form of single-bounce (unfocused) X-rays. We conducted a search for quiet-Sun transient brightenings on timescales...... as model-independent photon fluxes. The limits in both bands are well below previous HXR microflare detections, though not low enough to detect events of equivalent T and EM as quiet-Sun brightenings seen in soft X-ray observations. We expect future observations during solar minimum to increase the Nu...

  17. Minimum current principle and variational method in theory of space charge limited flow

    Energy Technology Data Exchange (ETDEWEB)

    Rokhlenko, A. [Department of Mathematics, Rutgers University, Piscataway, New Jersey 08854-8019 (United States)

    2015-10-21

    In spirit of the principle of least action, which means that when a perturbation is applied to a physical system, its reaction is such that it modifies its state to “agree” with the perturbation by “minimal” change of its initial state. In particular, the electron field emission should produce the minimum current consistent with boundary conditions. It can be found theoretically by solving corresponding equations using different techniques. We apply here the variational method for the current calculation, which can be quite effective even when involving a short set of trial functions. The approach to a better result can be monitored by the total current that should decrease when we on the right track. Here, we present only an illustration for simple geometries of devices with the electron flow. The development of these methods can be useful when the emitter and/or anode shapes make difficult the use of standard approaches. Though direct numerical calculations including particle-in-cell technique are very effective, but theoretical calculations can provide an important insight for understanding general features of flow formation and even sometimes be realized by simpler routines.

  18. Molecular techniques for detection and identification of pathogens in food: advantages and limitations

    OpenAIRE

    Palomino-Camargo, Carolina; Instituto de Ciencia y Tecnología de Alimentos, Facultad de Ciencias, Universidad Central de Venezuela. Caracas, Venezuela. Magíster en Ciencia y Tecnología de los Alimentos licenciada en Biología; González-Muñoz, Yuniesky; Instituto de Ciencia y Tecnología de Alimentos, Facultad de Ciencias, Universidad Central de Venezuela. Caracas, Venezuela. Ministerio del Poder Popular para la Alimentación. Caracas, Venezuela. licenciado en Ciencias de los Alimentos.

    2014-01-01

    Foodborne diseases, caused by pathogenic microorganisms, are a major public health problem worldwide. Microbiological methods commonly used in the detection of these foodborne pathogens are laborious and time consuming. This situation, coupled with the demand for immediate results and with technological advances, has led to the development of a wide range of rapid methods in recent decades. On this basis, this review describes the advantages and limitations of the main molecular methods used ...

  19. Minimum detection efficiencies for a loophole-free observable-asymmetric Bell-type test

    International Nuclear Information System (INIS)

    Garbarino, G.

    2010-01-01

    We discuss the problem of finding the most favorable conditions for closing the detection loophole in a test of local realism with a Bell inequality. For a generic nonmaximally entangled two-qubit state and two incompatible bases to be adopted for alternative measurements of two observables a and b on each party, we apply Hardy's proof of nonlocality without inequality and derive an Eberhard-like inequality. For an infinity of nonmaximally entangled states we find that it is possible to refute local realism by requiring perfect detection efficiency for only one of the two observables, say b, to be measured on each party: The test is free from the detection loophole for any value of the detection efficiency corresponding to the other observable a. The maximum tolerable noise in such a loophole-free observable-asymmetric test is also evaluated.

  20. Evaluation of the limits of visual detection of image misregistration in a brain fluorine-18 fluorodeoxyglucose PET-MRI study

    International Nuclear Information System (INIS)

    Wong, J.C.H.; Studholme, C.; Hawkes, D.J.; Maisey, M.N.

    1997-01-01

    In routine clinical work, registration accuracy is assessed by visual inspection. However, the accuracy of visual assessment of registration has not been evaluated. This study establishes the limits of visual detection of misregistration in a registered brain fluorine-18 fluorodeoxyglucose positron emission tomography to magnetic resonance image volume. The ''best'' registered image volume was obtained by automatic registration using mutual information optimization. Translational movements by 1 mm, 2 mm, 3 mm and 4 mm, and rotational movements by 1 , 2 , 3 and 4 in the positive and negative directions in the x- (lateral), y- (anterior-posterior) and z- (axial) axes were introduced to this standard. These 48 images plus six ''best'' registered images were presented in random sequence to five observers for visual categorization of registration accuracy. No observer detected a definite misregistration in the ''best'' registered image. Evaluation for inter-observer variation using observer pairings showed a high percentage of agreement in assigned categories for both translational and rotational misregistrations. Assessment of the limits of detection of misregistration showed that a 2-mm translational misregistration was detectable by all observers in the x- and y-axes and 3-mm translational misregistration in the z-axis. With rotational misregistrations, rotation around the z-axis was detectable by all at 2 rotation whereas rotation around the y-axis was detected at 3-4 . Rotation around the x-axis was not symmetric with a positive rotation being identified at 2 whereas negative rotation was detected by all only at 4 . Therefore, visual analysis appears to be a sensitive and practical means to assess image misregistration accuracy. The awareness of the limits of visual detection of misregistration will lead to increase care when evaluating registration quality in both research and clinical settings. (orig.). With 6 figs., 3 tabs

  1. Rate based failure detection

    Science.gov (United States)

    Johnson, Brett Emery Trabun; Gamage, Thoshitha Thanushka; Bakken, David Edward

    2018-01-02

    This disclosure describes, in part, a system management component and failure detection component for use in a power grid data network to identify anomalies within the network and systematically adjust the quality of service of data published by publishers and subscribed to by subscribers within the network. In one implementation, subscribers may identify a desired data rate, a minimum acceptable data rate, desired latency, minimum acceptable latency and a priority for each subscription. The failure detection component may identify an anomaly within the network and a source of the anomaly. Based on the identified anomaly, data rates and or data paths may be adjusted in real-time to ensure that the power grid data network does not become overloaded and/or fail.

  2. Analysis of uncertainties and detection limits for the double measurement method of {sup 90}Sr and {sup 89}Sr

    Energy Technology Data Exchange (ETDEWEB)

    Herranz, M., E-mail: m.herranz@ehu.es [Department of Nuclear Engineering and Fluid Mechanics, University of the Basque Country (UPV/EHU), Alameda de Urquijo s/n 48013 Bilbao (Spain); Idoeta, R.; Legarda, F. [Department of Nuclear Engineering and Fluid Mechanics, University of the Basque Country (UPV/EHU), Alameda de Urquijo s/n 48013 Bilbao (Spain)

    2011-08-15

    The determination process of the {sup 90}Sr and {sup 89}Sr contents in a sample, although it involves their radiochemical isolation, results always in a complex measurement process due to the interferences among their respective beta emissions and also among those of the daughter of {sup 90}Sr, {sup 90}Y, a beta emitter as well. In this paper, the process consisting in a double measurement method after the Sr radiochemical isolation is analyzed, developing the formulae to obtain activity concentrations, uncertainties and detection limits. A study of the trend of uncertainties and detection limits as function of the time in which the first measurement since the isolation is done, the delay between the two measurements and the activity concentration of each strontium isotope in the sample is carried out as well. Results show that with a very precise determination of the times involved in the whole process (isolation, measurement and duration of measurements) this method permits a reliable assessment of both strontium radioisotopes. The quicker the first measurement since the isolation is done and the longer the delay between measurements is chosen, the lower are the detection limits and the uncertainties of the activities obtained. - Highlights: > The double measurement method for {sup 90}Sr and {sup 89}Sr determination is analysed. > Uncertainties and detection limits are determined and their dependences studied. > Proposals for the optimization of the method are given.

  3. Lower limit of detection: definition and elaboration of a proposed position for radiological effluent and environmental measurements

    International Nuclear Information System (INIS)

    Currie, L.A.

    1984-09-01

    A manual is provided to define and illustrate a proposed use of the Lower Limit of Detection (LLD) for Radiological Effluent and Environmental Measurements. The manual contains a review of information regarding LLD practices gained from site visits; a review of the literature and a summary of basic principles underlying the concept of detection in Nuclear and Analytical Chemistry; a detailed presentation of the application of LLD principles to a range of problem categories (simple counting to multinuclide spectroscopy), including derivations, equations, and numerical examples; and a brief examination of related issues such as reference samples, numerical quality control, and instrumental limitations. An appendix contains a summary of notation and terminology, a bibliography, and worked-out examples. 100 references, 10 figures, 7 tables

  4. A Limit on the Warm Dark Matter Particle Mass from the Redshifted 21 cm Absorption Line

    Science.gov (United States)

    Safarzadeh, Mohammadtaher; Scannapieco, Evan; Babul, Arif

    2018-06-01

    The recent Experiment to Detect the Global Epoch of Reionization Signature (EDGES) collaboration detection of an absorption signal at a central frequency of ν = 78 ± 1 MHz points to the presence of a significant Lyα background by a redshift of z = 18. The timing of this signal constrains the dark matter particle mass (m χ ) in the warm dark matter (WDM) cosmological model. WDM delays the formation of small-scale structures, and therefore a stringent lower limit can be placed on m χ based on the presence of a sufficiently strong Lyα background due to star formation at z = 18. Our results show that coupling the spin temperature to the gas through Lyα pumping requires a minimum mass of m χ > 3 keV if atomic cooling halos dominate the star formation rate at z = 18, and m χ > 2 keV if {{{H}}}2 cooling halos also form stars efficiently at this redshift. These limits match or exceed the most stringent limits cited to date in the literature, even in the face of the many uncertainties regarding star formation at high redshift.

  5. A green, reusable SERS film with high sensitivity for in-situ detection of thiram in apple juice

    Science.gov (United States)

    Sun, Hongbao; Liu, Hai; Wu, Yiyong

    2017-09-01

    We report a green and reusable surface-enhanced Raman scattering (SERS) film based on PMMA/Ag NPs/graphene. By using this Raman substrate, the SERS signals of R6G were significantly enhanced reaching a minimum detectable concentration of 5 × 10-8 M, due to having lots of hot spots adhered backside to the exposed graphene. The SERS film can be used for in-situ monitoring of trace thiram in apple juice with a detection limit of 1 × 10-6 M (0.24 ppm), which is below the maximal residue limit (MRL) of 7 ppm in fruit prescribed by the U.S. Environmental Protection Agency (EPA). Furthermore, reusability studies show that the SERS film can be used repeatedly. In addition, the graphene-enhanced SERS technique shows great potential applications for the in-situ detection and identification of pesticide residues in environmental water, fruits and vegetables.

  6. 12 CFR 564.4 - Minimum appraisal standards.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Minimum appraisal standards. 564.4 Section 564.4 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY APPRAISALS § 564.4 Minimum appraisal standards. For federally related transactions, all appraisals shall, at a minimum: (a...

  7. The minimum wage in the Czech enterprises

    OpenAIRE

    Eva Lajtkepová

    2010-01-01

    Although the statutory minimum wage is not a new category, in the Czech Republic we encounter the definition and regulation of a minimum wage for the first time in the 1990 amendment to Act No. 65/1965 Coll., the Labour Code. The specific amount of the minimum wage and the conditions of its operation were then subsequently determined by government regulation in February 1991. Since that time, the value of minimum wage has been adjusted fifteenth times (the last increase was in January 2007). ...

  8. Minimum Wages and Regional Disparity: An analysis on the evolution of price-adjusted minimum wages and their effects on firm profitability (Japanese)

    OpenAIRE

    MORIKAWA Masayuki

    2013-01-01

    This paper, using prefecture level panel data, empirically analyzes 1) the recent evolution of price-adjusted regional minimum wages and 2) the effects of minimum wages on firm profitability. As a result of rapid increases in minimum wages in the metropolitan areas since 2007, the regional disparity of nominal minimum wages has been widening. However, the disparity of price-adjusted minimum wages has been shrinking. According to the analysis of the effects of minimum wages on profitability us...

  9. Amorphous semiconductors for particle detection: Physical and technical limits and possibilities

    International Nuclear Information System (INIS)

    Equer, B.; Karar, A.

    1989-01-01

    Amorphous silicon is used, at an industrial level, in at least three different fields of application: photovoltaic cells, flat TV screens and line scanners for image processing. In the last two cases, thin film transistors (TFT) are produced with the same technology. Particle detection with amorphous silicon has been demonstrated, but present performances are limited to ionizing particles. In this paper, we discuss the physical basis of amorphous semiconductors and the possible future development that can be expected on the basis of the existing technology. It is concluded that substitution of amorphous for crystalline silicon brings no clear advantage, if possible at all. Positive assets are to be found in using specific properties of thin layers: large area structures like arrays of photodiodes with associated readout are in the state of the art; vertical structures alternating layers of differently doped materials and/or of different semiconductors can be produced by the same technique. The development of large area pixel detectors is technically feasible but requires a very large effort. A joint development effort with industries involved in X-ray detection and 2D photodetectors might be the most appropriate solution. (orig.)

  10. Minimum entropy density method for the time series analysis

    Science.gov (United States)

    Lee, Jeong Won; Park, Joongwoo Brian; Jo, Hang-Hyun; Yang, Jae-Suk; Moon, Hie-Tae

    2009-01-01

    The entropy density is an intuitive and powerful concept to study the complicated nonlinear processes derived from physical systems. We develop the minimum entropy density method (MEDM) to detect the structure scale of a given time series, which is defined as the scale in which the uncertainty is minimized, hence the pattern is revealed most. The MEDM is applied to the financial time series of Standard and Poor’s 500 index from February 1983 to April 2006. Then the temporal behavior of structure scale is obtained and analyzed in relation to the information delivery time and efficient market hypothesis.

  11. 41 CFR 50-201.1101 - Minimum wages.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Minimum wages. 50-201... Contracts PUBLIC CONTRACTS, DEPARTMENT OF LABOR 201-GENERAL REGULATIONS § 50-201.1101 Minimum wages. Determinations of prevailing minimum wages or changes therein will be published in the Federal Register by the...

  12. Mechanisms Controlling Species Responses to Climate Change: Thermal Tolerances and Shifting Range Limits. (Invited)

    Science.gov (United States)

    Sage, R. F.; Bykova, O.; Coiner, H.

    2010-12-01

    One of the main effects of anthropogenic climate change will be widespread shifts in species distribution, with the common assumption that they will migrate to higher elevation and latitude. While this assumption is supported by migration patterns following climate warming in the past 20,000 years, it has not been rigorously evaluated in terms of physiological mechanism, despite the implication that migration in response to climate warming is controlled by some form of thermal adaptation. We have been evaluating the degree to which species range limits are controlled by physiological patterns of thermal tolerance in bioinvaders of North America. Bioinvaders presumably have few biotic controls over their distribution and thus are more likely to fully exploit their thermal niche. In cheatgrass (Bromus tectorum), the minimum lethal temperature in winter is -32C, which corresponds to the mean winter minimum temperature at its northern range limit. In red brome (Bromus rubens), the minimum lethal temperature is also near -32C, which is well below the minimum winter temperature near -20C that corresponds to its northern distribution limit. In kudzu (Pueraria lobata), the minimum lethal temperature is near -20C, which corresponds to the midwinter minimum at its northern distribution limit; however, overwintering kudzu tissues are insulated by soil and snow cover, and thus do not experience lethal temperatures at kudzu's northern range limit. These results demonstrate that some invasive species can exploit the potential range defined by their low temperature tolerance and thus can be predicted by mechanistic models to migrate to higher latitudes with moderation of winter cold. The distribution of other invaders such as kudzu and red brome are not controlled by tolerance of midwinter cold. Developing mechanistic models of their distributions, and how these might change with climate warming, will require extensive physiological study.

  13. Enhancement of laser-induced breakdown spectroscopy (LIBS) Detection limit using a low-pressure and short-pulse laser-induced plasma process.

    Science.gov (United States)

    Wang, Zhen Zhen; Deguchi, Yoshihiro; Kuwahara, Masakazu; Yan, Jun Jie; Liu, Ji Ping

    2013-11-01

    Laser-induced breakdown spectroscopy (LIBS) technology is an appealing technique compared with many other types of elemental analysis because of the fast response, high sensitivity, real-time, and noncontact features. One of the challenging targets of LIBS is the enhancement of the detection limit. In this study, the detection limit of gas-phase LIBS analysis has been improved by controlling the pressure and laser pulse width. In order to verify this method, low-pressure gas plasma was induced using nanosecond and picosecond lasers. The method was applied to the detection of Hg. The emission intensity ratio of the Hg atom to NO (IHg/INO) was analyzed to evaluate the LIBS detection limit because the NO emission (interference signal) was formed during the plasma generation and cooling process of N2 and O2 in the air. It was demonstrated that the enhancement of IHg/INO arose by decreasing the pressure to a few kilopascals, and the IHg/INO of the picosecond breakdown was always much higher than that of the nanosecond breakdown at low buffer gas pressure. Enhancement of IHg/INO increased more than 10 times at 700 Pa using picosecond laser with 35 ps pulse width. The detection limit was enhanced to 0.03 ppm (parts per million). We also saw that the spectra from the center and edge parts of plasma showed different features. Comparing the central spectra with the edge spectra, IHg/INO of the edge spectra was higher than that of the central spectra using the picosecond laser breakdown process.

  14. Minimum Wage Laws and the Distribution of Employment.

    Science.gov (United States)

    Lang, Kevin

    The desirability of raising the minimum wage long revolved around just one question: the effect of higher minimum wages on the overall level of employment. An even more critical effect of the minimum wage rests on the composition of employment--who gets the minimum wage job. An examination of employment in eating and drinking establishments…

  15. 29 CFR 505.3 - Prevailing minimum compensation.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Prevailing minimum compensation. 505.3 Section 505.3 Labor... HUMANITIES § 505.3 Prevailing minimum compensation. (a)(1) In the absence of an alternative determination...)(2) of this section, the prevailing minimum compensation required to be paid under the Act to the...

  16. Assessment of Hydrogen Sulfide Minimum Detection Limits of an Open Path Tunable Diode Laser

    Science.gov (United States)

    During June 2007, U.S. EPA conducted a feasibility study to determine whether the EPA OTM 10 measurement approach, also known as radial plume mapping (RPM), was feasible. A Boreal open-path tunable diode laser (OP-TDL) to collect path-integrated hydrogen sulfide measurements alon...

  17. A novel dNTP-limited PCR and HRM assay to detect Williams-Beuren syndrome.

    Science.gov (United States)

    Zhang, Lichen; Zhang, Xiaoqing; You, Guoling; Yu, Yongguo; Fu, Qihua

    2018-06-01

    Williams-Beuren syndrome (WBS) is caused by a microdeletion of chromosome arm 7q11.23. A rapid and inexpensive genotyping method to detect microdeletion on 7q11.23 needs to be developed for the diagnosis of WBS. This study describes the development of a new type of molecular diagnosis method to detect microdeletion on 7q11.23 based upon high-resolution melting (HRM). Four genes on 7q11.23 were selected as the target genes for the deletion genotyping. dNTP-limited duplex PCR was used to amplify the reference gene, CFTR, and one of the four genes respectively on 7q11.23. An HRM assay was performed on the PCR products, and the height ratio of the negative derivative peaks between the target gene and reference gene was employed to analyze the copy number variation of the target region. A new genotyping method for detecting 7q11.23 deletion was developed based upon dNTP-limited PCR and HRM, which cost only 96 min. Samples from 15 WBS patients and 12 healthy individuals were genotyped by this method in a blinded fashion, and the sensitivity and specificity was 100% (95% CI, 0.80-1, and 95% CI, 0.75-1, respectively) which was proved by CytoScan HD array. The HRM assay we developed is an rapid, inexpensive, and highly accurate method for genotyping 7q11.23 deletion. It is potentially useful in the clinical diagnosis of WBS. Copyright © 2018 Elsevier B.V. All rights reserved.

  18. Neutron activation analysis detection limits using 252Cf sources

    International Nuclear Information System (INIS)

    DiPrete, D.P.; Sigg, R.A.

    2000-01-01

    The Savannah River Technology Center (SRTC) developed a neutron activation analysis (NAA) facility several decades ago using low-flux 252 Cf neutron sources. Through this time, the facility has addressed areas of applied interest in managing the Savannah River Site (SRS). Some applications are unique because of the site's operating history and its chemical-processing facilities. Because sensitivity needs for many applications are not severe, they can be accomplished using an ∼6-mg 252 Cf NAA facility. The SRTC 252 Cf facility continues to support applied research programs at SRTC as well as other SRS programs for environmental and waste management customers. Samples analyzed by NAA include organic compounds, metal alloys, sediments, site process solutions, and many other materials. Numerous radiochemical analyses also rely on the facility for production of short-lived tracers, yielding by activation of carriers and small-scale isotope production for separation methods testing. These applications are more fully reviewed in Ref. 1. Although the flux [approximately2 x 10 7 n/cm 2 ·s] is low relative to reactor facilities, more than 40 elements can be detected at low and sub-part-per-million levels. Detection limits provided by the facility are adequate for many analytical projects. Other multielement analysis methods, particularly inductively coupled plasma atomic emission and inductively coupled plasma mass spectrometry, can now provide sensitivities on dissolved samples that are often better than those available by NAA using low-flux isotopic sources. Because NAA allows analysis of bulk samples, (a) it is a more cost-effective choice when its sensitivity is adequate than methods that require digestion and (b) it eliminates uncertainties that can be introduced by digestion processes

  19. A Review of Voiture Minimum. Le Corbusier and the Automobile

    Directory of Open Access Journals (Sweden)

    Christoph Schnoor

    2013-03-01

    Full Text Available Here is a full-on celebration of cars and someone’s addiction to cars. In its midst drives Le Corbusier. The book, Voiture Minimum. Le Corbusier and the Automobile (Cambridge, Mass. and London: MIT Press, 2011, has recently been published by Spanish architect and academic Antonio Amado. What a curious book. It is something between a detective story circling around determining the date of a single drawing (1928 or 1936 and, simultaneously, it is “Everything you always wanted to know about Le Corbusier and cars but were afraid to ask”.

  20. Do Some Workers Have Minimum Wage Careers?

    Science.gov (United States)

    Carrington, William J.; Fallick, Bruce C.

    2001-01-01

    Most workers who begin their careers in minimum-wage jobs eventually gain more experience and move on to higher paying jobs. However, more than 8% of workers spend at least half of their first 10 working years in minimum wage jobs. Those more likely to have minimum wage careers are less educated, minorities, women with young children, and those…

  1. Does the Minimum Wage Affect Welfare Caseloads?

    Science.gov (United States)

    Page, Marianne E.; Spetz, Joanne; Millar, Jane

    2005-01-01

    Although minimum wages are advocated as a policy that will help the poor, few studies have examined their effect on poor families. This paper uses variation in minimum wages across states and over time to estimate the impact of minimum wage legislation on welfare caseloads. We find that the elasticity of the welfare caseload with respect to the…

  2. 29 CFR 4.159 - General minimum wage.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true General minimum wage. 4.159 Section 4.159 Labor Office of... General minimum wage. The Act, in section 2(b)(1), provides generally that no contractor or subcontractor... a contract less than the minimum wage specified under section 6(a)(1) of the Fair Labor Standards...

  3. A program for the a priori evaluation of detection limits in instrumental neutron activation analysis using a SLOWPOKE II reactor

    International Nuclear Information System (INIS)

    Galinier, J.L.; Zikovsky, L.

    1982-01-01

    A program that permits the a priori calculation of detection limits in monoelemental matrices, adapted to instrumental neutron activation analysis using a SLOWPOKE II reactor, is described. A simplified model of the gamma spectra is proposed. Products of (n,p) and (n,α) reactions induced by the fast components of the neutron flux that accompanies the thermal flux at the level of internal irradiation sites in the reactor have been included in the list of interfering radionuclides. The program calculates in a systematic way the detection limits of 66 elements in an equal number of matrices using 153 intermediary radionuclides. Experimental checks carried out with silicon (for short lifetimes) and aluminum and magnesium (for intermediate lifetimes) show satisfactory agreement with the calculations. These results show in particular the importance of the contribution of the (n,p) and (n,α) reactions in the a priori evaluation of detection limits with a SLOWPOKE type reactor [fr

  4. Re-evaluation of groundwater monitoring data for glyphosate and bentazone by taking detection limits into account

    DEFF Research Database (Denmark)

    Hansen, Claus Toni; Ritz, Christian; Gerhard, Daniel

    2015-01-01

    .e. samples with concentrations below the detection limit, as left-censored observations. The median calculated pesticide concentrations are shown to be reduced 10(4) to 10(5) fold for two representative herbicides (glyphosate and bentazone) relative to the median concentrations based upon observations above...

  5. Zero-Forcing and Minimum Mean-Square Error Multiuser Detection in Generalized Multicarrier DS-CDMA Systems for Cognitive Radio

    Directory of Open Access Journals (Sweden)

    Lie-Liang Yang

    2008-01-01

    Full Text Available In wireless communications, multicarrier direct-sequence code-division multiple access (MC DS-CDMA constitutes one of the highly flexible multiple access schemes. MC DS-CDMA employs a high number of degrees-of-freedom, which are beneficial to design and reconfiguration for communications in dynamic communications environments, such as in the cognitive radios. In this contribution, we consider the multiuser detection (MUD in MC DS-CDMA, which motivates lowcomplexity, high flexibility, and robustness so that the MUD schemes are suitable for deployment in dynamic communications environments. Specifically, a range of low-complexity MUDs are derived based on the zero-forcing (ZF, minimum mean-square error (MMSE, and interference cancellation (IC principles. The bit-error rate (BER performance of the MC DS-CDMA aided by the proposed MUDs is investigated by simulation approaches. Our study shows that, in addition to the advantages provided by a general ZF, MMSE, or IC-assisted MUD, the proposed MUD schemes can be implemented using modular structures, where most modules are independent of each other. Due to the independent modular structure, in the proposed MUDs one module may be reconfigured without yielding impact on the others. Therefore, the MC DS-CDMA, in conjunction with the proposed MUDs, constitutes one of the promising multiple access schemes for communications in the dynamic communications environments such as in the cognitive radios.

  6. Zero-Forcing and Minimum Mean-Square Error Multiuser Detection in Generalized Multicarrier DS-CDMA Systems for Cognitive Radio

    Directory of Open Access Journals (Sweden)

    Wang Li-Chun

    2008-01-01

    Full Text Available Abstract In wireless communications, multicarrier direct-sequence code-division multiple access (MC DS-CDMA constitutes one of the highly flexible multiple access schemes. MC DS-CDMA employs a high number of degrees-of-freedom, which are beneficial to design and reconfiguration for communications in dynamic communications environments, such as in the cognitive radios. In this contribution, we consider the multiuser detection (MUD in MC DS-CDMA, which motivates lowcomplexity, high flexibility, and robustness so that the MUD schemes are suitable for deployment in dynamic communications environments. Specifically, a range of low-complexity MUDs are derived based on the zero-forcing (ZF, minimum mean-square error (MMSE, and interference cancellation (IC principles. The bit-error rate (BER performance of the MC DS-CDMA aided by the proposed MUDs is investigated by simulation approaches. Our study shows that, in addition to the advantages provided by a general ZF, MMSE, or IC-assisted MUD, the proposed MUD schemes can be implemented using modular structures, where most modules are independent of each other. Due to the independent modular structure, in the proposed MUDs one module may be reconfigured without yielding impact on the others. Therefore, the MC DS-CDMA, in conjunction with the proposed MUDs, constitutes one of the promising multiple access schemes for communications in the dynamic communications environments such as in the cognitive radios.

  7. On the definition of the detection limit for non-selective determination of low activities

    International Nuclear Information System (INIS)

    Tschurlovits, M.

    1977-01-01

    Based on the latest published results, a detection limit which is easy to use in practical work without intensive consideration of counting statistics, is presented. The primary application of the given definition is the determination of gross activity. In the definition the error of the second kind as well as one-sided boundedness of the normal distribution are included. The results are given in graphical form. (orig.) [de

  8. [Validation of the Kit for Detecting Mycoplasma Genitalium from the Male Urethritis].

    Science.gov (United States)

    Hamasuna, Ryoichi; Matsumoto, Masahiro; Thi LE, Phuong; Fujimoto, Naohiro; Matsumoto, Tetsuro

    Mycoplasma genitalium is one of the pathogenic microorganisms in male urethritis as a sexually transmitted infection (STI). M.genitalium is detected in the urine specimens of 15-25% male patients with urethritis. The emergence of macrolide- or fluoroquinolone-resistant M.genitalium has become a serious problem in the treatment of male urethritis worldwide, but there is no commercial-based detecting kits accepted by the national insurance in Japan. In this study, we tested the validity of a molecular kit for detecting seven microorganisms related to STI (Anyplex™ II STI-7 Detection which detects Neisseria gonorrhoeae, Chlamydia trachomatis, M.genitalium, Mycoplasma hominis, Ureaplasma urealyticum, Ureaplasma parvum, Trichomonas vaginalis) produced by Seegene company in Korea. Seventeen M.genitalium strains were used to determine the detection limit of M.genitalium. M.genitalium DNA samples were extracted from M.genitalium strains and the diluted DNA samples were reacted to detect M.genitalium by the Anyplex™ II STI-7 Detection. The detection limit was determined as the maximum dilution of DNA samples and the number of M.genitalium DNA copies calculated. In this study, the minimum DNA copies to detect M.genitalium by the Anyplex™ II STI-7 Detection was determined to be around 50 per reaction. The detection rates of M.genitalium in urine specimens were compared between MgPa gene PCR and the Anyplex™ II STI-7 Detection. The positive and negative concordant rates were high as 96.4% (27/28) and 98.6% (71/72), respectively. The validity of the kit for detecting seven microorganisms related to STI (Anyplex™ II STI-7 Detection) was high and thought to be useful for clinical uses.

  9. Experimental investigations of the minimum ignition energy and the minimum ignition temperature of inert and combustible dust cloud mixtures

    Energy Technology Data Exchange (ETDEWEB)

    Addai, Emmanuel Kwasi, E-mail: emmanueladdai41@yahoo.com; Gabel, Dieter; Krause, Ulrich

    2016-04-15

    Highlights: • Ignition sensitivity of a highly flammable dust decreases upon addition of inert dust. • Minimum ignition temperature of a highly flammable dust increases when inert concentration increase. • Minimum ignition energy of a highly flammable dust increases when inert concentration increase. • The permissible range for the inert mixture to minimize the ignition risk lies between 60 to 80%. - Abstract: The risks associated with dust explosions still exist in industries that either process or handle combustible dust. This explosion risk could be prevented or mitigated by applying the principle of inherent safety (moderation). This is achieved by adding an inert material to a highly combustible material in order to decrease the ignition sensitivity of the combustible dust. The presented paper deals with the experimental investigation of the influence of adding an inert dust on the minimum ignition energy and the minimum ignition temperature of the combustible/inert dust mixtures. The experimental investigation was done in two laboratory scale equipment: the Hartmann apparatus and the Godbert-Greenwald furnace for the minimum ignition energy and the minimum ignition temperature test respectively. This was achieved by mixing various amounts of three inert materials (magnesium oxide, ammonium sulphate and sand) and six combustible dusts (brown coal, lycopodium, toner, niacin, corn starch and high density polyethylene). Generally, increasing the inert materials concentration increases the minimum ignition energy as well as the minimum ignition temperatures until a threshold is reached where no ignition was obtained. The permissible range for the inert mixture to minimize the ignition risk lies between 60 to 80%.

  10. Experimental investigations of the minimum ignition energy and the minimum ignition temperature of inert and combustible dust cloud mixtures

    International Nuclear Information System (INIS)

    Addai, Emmanuel Kwasi; Gabel, Dieter; Krause, Ulrich

    2016-01-01

    Highlights: • Ignition sensitivity of a highly flammable dust decreases upon addition of inert dust. • Minimum ignition temperature of a highly flammable dust increases when inert concentration increase. • Minimum ignition energy of a highly flammable dust increases when inert concentration increase. • The permissible range for the inert mixture to minimize the ignition risk lies between 60 to 80%. - Abstract: The risks associated with dust explosions still exist in industries that either process or handle combustible dust. This explosion risk could be prevented or mitigated by applying the principle of inherent safety (moderation). This is achieved by adding an inert material to a highly combustible material in order to decrease the ignition sensitivity of the combustible dust. The presented paper deals with the experimental investigation of the influence of adding an inert dust on the minimum ignition energy and the minimum ignition temperature of the combustible/inert dust mixtures. The experimental investigation was done in two laboratory scale equipment: the Hartmann apparatus and the Godbert-Greenwald furnace for the minimum ignition energy and the minimum ignition temperature test respectively. This was achieved by mixing various amounts of three inert materials (magnesium oxide, ammonium sulphate and sand) and six combustible dusts (brown coal, lycopodium, toner, niacin, corn starch and high density polyethylene). Generally, increasing the inert materials concentration increases the minimum ignition energy as well as the minimum ignition temperatures until a threshold is reached where no ignition was obtained. The permissible range for the inert mixture to minimize the ignition risk lies between 60 to 80%.

  11. Internal Dosimetry Monitoring- Detection Limits for a Selected Set of Radionuclides and Their Translation Into Committed Effective Dose

    International Nuclear Information System (INIS)

    Brandl, A.; Hrnecek, E.; Steger, F.

    2004-01-01

    To harmonize the practice of internal dosimetry monitoring across the country, the Austrian Standards Institute is currently drafting a new set of standards which are concerned with occupational incorporation monitoring of individuals handling non-sealed radioactive material. This set of standards is expected to consist of three parts discussing the general necessity and frequency, the requirements for monitoring institutions, and the determination and rigorous calculation of committed effective dose after incorporation of radioactive material, respectively. Considerations of the requirements for routine monitoring laboratories have led to an evaluation of the detection limits for routine monitoring equipment. For a selected set of radionuclides, these detection limits are investigated in detail. The main emphasis is placed on the decay chains of naturally occurring radionuclides showing some significant potential for being out of equilibrium due to chemical processes in certain mining industries. The radionuclides considered in this paper are 226Ra, 228Ra, 228Th, 232Th, 234U, 235U, and 238U. Given the routine monitoring intervals of the Austrian Standard, these detection limits are translated into information on committed effective dose. This paper investigates whether routine monitoring equipment is sufficient to ensure compliance with EC directive 96/29/Euratom for this selected set of radionuclides. (Author) 9 refs

  12. Comparison of detection limits in environmental analysis--is it possible? An approach on quality assurance in the lower working range by verification.

    Science.gov (United States)

    Geiss, S; Einax, J W

    2001-07-01

    Detection limit, reporting limit and limit of quantitation are analytical parameters which describe the power of analytical methods. These parameters are used for internal quality assurance and externally for competing, especially in the case of trace analysis in environmental compartments. The wide variety of possibilities for computing or obtaining these measures in literature and in legislative rules makes any comparison difficult. Additionally, a host of terms have been used within the analytical community to describe detection and quantitation capabilities. Without trying to create an order for the variety of terms, this paper is aimed at providing a practical proposal for answering the main questions for the analysts concerning quality measures above. These main questions and related parameters were explained and graphically demonstrated. Estimation and verification of these parameters are the two steps to get real measures. A rule for a practical verification is given in a table, where the analyst can read out what to measure, what to estimate and which criteria have to be fulfilled. In this manner verified parameters detection limit, reporting limit and limit of quantitation now are comparable and the analyst himself is responsible to the unambiguity and reliability of these measures.

  13. New Minimum Wage Research: A Symposium.

    Science.gov (United States)

    Ehrenberg, Ronald G.; And Others

    1992-01-01

    Includes "Introduction" (Ehrenberg); "Effect of the Minimum Wage [MW] on the Fast-Food Industry" (Katz, Krueger); "Using Regional Variation in Wages to Measure Effects of the Federal MW" (Card); "Do MWs Reduce Employment?" (Card); "Employment Effects of Minimum and Subminimum Wages" (Neumark,…

  14. Development and calibration of a portable detection device for in vivo measurement of high-energy photon emitters incorporated by humans

    International Nuclear Information System (INIS)

    Soares, A.B.; Arbach, M.N.; Lucena, E.A.; Dantas, A.L.A.; Dantas, B.M.

    2017-01-01

    This work presents the evaluation of the applicability and sensitivity of a portable detection device specially designed for in vivo measurement of high-energy photon emitters in the human body. The calibration was performed at the In-Vivo Monitoring Laboratory of the IRD. The equipment consists of a lead-collimated NaI (Tl) 3″ x 3″ scintillation detector assembled on a tripod. The detector and its compact associated electronics are connected via USB cable to a portable PC. Spectrum acquisition and analysis is controlled by specific commercially available software. The calibration was performed using a standard liquid source of 152 Eu contained in 3 L polyethylene bottles. The evaluation of the system is based on the estimation of the minimum committed effective doses associated to the minimum detectable activities, calculated using current biokinetic and dosimetric models available in the literature. The dose detection limits for selected radionuclides of interest in an emergency scenario have shown to be far below 1 mSv allowing the system to be useful in accident situations. (author)

  15. Development and calibration of a portable detection device for in vivo measurement of high-energy photon emitters incorporated by humans

    Energy Technology Data Exchange (ETDEWEB)

    Soares, A.B.; Arbach, M.N.; Lucena, E.A.; Dantas, A.L.A.; Dantas, B.M., E-mail: alexandrebaso@globo.com [Instituto de Radioproteção e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil). Lab. de Monitoração Interna

    2017-07-01

    This work presents the evaluation of the applicability and sensitivity of a portable detection device specially designed for in vivo measurement of high-energy photon emitters in the human body. The calibration was performed at the In-Vivo Monitoring Laboratory of the IRD. The equipment consists of a lead-collimated NaI (Tl) 3″ x 3″ scintillation detector assembled on a tripod. The detector and its compact associated electronics are connected via USB cable to a portable PC. Spectrum acquisition and analysis is controlled by specific commercially available software. The calibration was performed using a standard liquid source of {sup 152}Eu contained in 3 L polyethylene bottles. The evaluation of the system is based on the estimation of the minimum committed effective doses associated to the minimum detectable activities, calculated using current biokinetic and dosimetric models available in the literature. The dose detection limits for selected radionuclides of interest in an emergency scenario have shown to be far below 1 mSv allowing the system to be useful in accident situations. (author)

  16. Teaching the Minimum Wage in Econ 101 in Light of the New Economics of the Minimum Wage.

    Science.gov (United States)

    Krueger, Alan B.

    2001-01-01

    Argues that the recent controversy over the effect of the minimum wage on employment offers an opportunity for teaching introductory economics. Examines eight textbooks to determine topic coverage but finds little consensus. Describes how minimum wage effects should be taught. (RLH)

  17. Minimum heat flux (MHF) point in pool and external-flow boiling

    International Nuclear Information System (INIS)

    Nishio, Shigefumi

    1983-01-01

    As for the boiling phenomena near a minimum heat flux (MHF) point to which attention has been paid recently concerning the safety analysis of LWR cores, the results of research have not been put in order sufficiently. Therefore in this explanation, the object is limited to pool boiling and external flow boiling, and it is attempted to rearrange the present knowledge on the phenomena near a MHF point from the viewpoint of the relation to the state of solid-liquid contact, the effect of various factors on a MHF point and the modeling of a MHF point. The heat transfer characteristics in boiling phenomena are represented by a curve with one maximum and one minimum points. The MHF point is called also minimum film boiling point. In a heat flux-controlled heating surface, temperature jump arises when heat flux is decreased at a MHF point. The phenomena near a MHF point and the technological background when a MHF point becomes a problem are explained. Near a MHF point, only partial, intermittent solid-liquid contact is maintained. The effects of solid-liquid contact mode, the geometry of a heating surface, pressure and others on a MHF point are discussed. (Kako, I.)

  18. DETERMINATION OF LIMIT DETECTION OF THE ELEMENTS N, P, K, Si, Al, Fe, Cu, Cd, WITH FAST NEUTRON ACTIVATION USING NEUTRON GENERATOR

    Directory of Open Access Journals (Sweden)

    Sunardi Sunardi

    2010-06-01

    Full Text Available Determination of limit detection of the elements N, P, K, Si, Al, Fe, Cu, Cd, with fast neutron activation using neutron generator has been done.  Samples prepared from SRM 2704, N, P, K elements from MERCK, Cu, Cd, Al from activation foil made in San Carlos, weighted and packed for certain weight then iradiated during 30 minutes with 14 MeV fast neutron using the neutron generator and then counted with gamma spectrometry (accuspec.  At this research condition of neutron generator was set at current 1 mA that produced neutron flux about 5,47.107 n/cm2.s and  experimental result shown that the limit detection for the elements N, P, K, Si, Al, Fe, Cu, Cd are  2,44 ppm, 1,88 ppm, 2,15 ppm, 1,44 ppm, 1,26 ppm, 1,35 ppm, 1,05 ppm, 2,99 ppm, respectively.  The data  indicate that the limit detection or sensitivity of appliance of neutron generator to analyze the element is very good, which is feasible to get accreditation AANC laboratory using neutron generator.   Keywords: limit detection, AANC, neutron generator

  19. 30 CFR 75.1431 - Minimum rope strength.

    Science.gov (United States)

    2010-07-01

    ..., including rotation resistant). For rope lengths less than 3,000 feet: Minimum Value=Static Load×(7.0−0.001L) For rope lengths 3,000 feet or greater: Minimum Value=Static Load×4.0 (b) Friction drum ropes. For rope lengths less than 4,000 feet: Minimum Value=Static Load×(7.0−0.0005L) For rope lengths 4,000 feet...

  20. Near-Threshold Computing and Minimum Supply Voltage of Single-Rail MCML Circuits

    Directory of Open Access Journals (Sweden)

    Ruiping Cao

    2014-01-01

    Full Text Available In high-speed applications, MOS current mode logic (MCML is a good alternative. Scaling down supply voltage of the MCML circuits can achieve low power-delay product (PDP. However, the current almost all MCML circuits are realized with dual-rail scheme, where the NMOS configuration in series limits the minimum supply voltage. In this paper, single-rail MCML (SRMCML circuits are described, which can avoid the devices configuration in series, since their logic evaluation block can be realized by only using MOS devices in parallel. The relationship between the minimum supply voltage of the SRMCML circuits and the model parameters of MOS transistors is derived, so that the minimum supply voltage can be estimated before circuit designs. An MCML dynamic flop-flop based on SRMCML is also proposed. The optimization algorithm for near-threshold sequential circuits is presented. A near-threshold SRMCML mode-10 counter based on the optimization algorithm is verified. Scaling down the supply voltage of the SRMCML circuits is also investigated. The power dissipation, delay, and power-delay products of these circuits are carried out. The results show that the near-threshold SRMCML circuits can obtain low delay and small power-delay product.

  1. Detection of actinides and rare earths in natural matrices with the AGLAE new, high sensitivity detection set-up

    Science.gov (United States)

    Zucchiatti, Alessandro; Alonso, Ursula; Lemasson, Quentin; Missana, Tiziana; Moignard, Brice; Pacheco, Claire; Pichon, Laurent; Camarena de la Mora, Sandra

    2014-08-01

    A series of granite samples (Grimsel and Äspö) enriched by sorption with natU (10-3 M, 10-4 M, 10-5 M in solution) and La (10-3 M, 10-4 M in solution) has been scanned by PIXE over a surface of 1920 × 1920 mm2 together with non-enriched Grimsel and Äspö granites and a glass standard. An assessment of minimum detection limits, MDL's, for several elements has been performed with the use of standard materials. Due to mapping and the high sensitivity of the new AGLAE detection system, U levels around 30 ppm can be detected from the whole PIXE spectrum (one low energy detector and four summed filtered detectors) while U reach grains, inhomogeneously distributed over the surface can be clearly identified through the multi elemental maps and analyzed separately. Even the nominally enriched samples have La levels below the MDL, probably because precipitation of the element (and not adsorption) mostly took place, and precipitates were eliminated after surface cleaning carried out before PIXE analyses. A multi detector system that implies a PIXE detection solid angle much wider than in any other similar set-up (a factor of 2-5); a higher events selectivity, given by the possibility of filtering individually up to 4 PIXE detectors; a double RBS detector, the new Ion Beam Induced Luminescence (IBIL) spectrometry and gamma spectrometry. Full mapping capability in air, assisted by a powerful event by event reconstruction software. These features allow lower Minimum Detection Limits (MDL) which are highly beneficial to the analysis of cultural heritage objects, meaning generally a reduction of irradiation time. Paintings will then be studied without any damage to the pigments that have color change tendencies which is a major drawback of the previous system. Alternatively they could allow an increase in information collected at equal time, particularly considering the detector's fast response and therefore the potential for high beam currents when sample damage can be

  2. Generalized linear mixed model for binary outcomes when covariates are subject to measurement errors and detection limits.

    Science.gov (United States)

    Xie, Xianhong; Xue, Xiaonan; Strickler, Howard D

    2018-01-15

    Longitudinal measurement of biomarkers is important in determining risk factors for binary endpoints such as infection or disease. However, biomarkers are subject to measurement error, and some are also subject to left-censoring due to a lower limit of detection. Statistical methods to address these issues are few. We herein propose a generalized linear mixed model and estimate the model parameters using the Monte Carlo Newton-Raphson (MCNR) method. Inferences regarding the parameters are made by applying Louis's method and the delta method. Simulation studies were conducted to compare the proposed MCNR method with existing methods including the maximum likelihood (ML) method and the ad hoc approach of replacing the left-censored values with half of the detection limit (HDL). The results showed that the performance of the MCNR method is superior to ML and HDL with respect to the empirical standard error, as well as the coverage probability for the 95% confidence interval. The HDL method uses an incorrect imputation method, and the computation is constrained by the number of quadrature points; while the ML method also suffers from the constrain for the number of quadrature points, the MCNR method does not have this limitation and approximates the likelihood function better than the other methods. The improvement of the MCNR method is further illustrated with real-world data from a longitudinal study of local cervicovaginal HIV viral load and its effects on oncogenic HPV detection in HIV-positive women. Copyright © 2017 John Wiley & Sons, Ltd.

  3. Applying ISO 11929:2010 Standard to detection limit calculation in least-squares based multi-nuclide gamma-ray spectrum evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Kanisch, G., E-mail: guenter.kanisch@hanse.net

    2017-05-21

    The concepts of ISO 11929 (2010) are applied to evaluation of radionuclide activities from more complex multi-nuclide gamma-ray spectra. From net peak areas estimated by peak fitting, activities and their standard uncertainties are calculated by weighted linear least-squares method with an additional step, where uncertainties of the design matrix elements are taken into account. A numerical treatment of the standard's uncertainty function, based on ISO 11929 Annex C.5, leads to a procedure for deriving decision threshold and detection limit values. The methods shown allow resolving interferences between radionuclide activities also in case of calculating detection limits where they can improve the latter by including more than one gamma line per radionuclide. The co'mmon single nuclide weighted mean is extended to an interference-corrected (generalized) weighted mean, which, combined with the least-squares method, allows faster detection limit calculations. In addition, a new grouped uncertainty budget was inferred, which for each radionuclide gives uncertainty budgets from seven main variables, such as net count rates, peak efficiencies, gamma emission intensities and others; grouping refers to summation over lists of peaks per radionuclide.

  4. Limitation of radioactive discharges from NPP based on radionuclide specific monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Bucina, I; Malatova, I; Vidlakova, J [National Radaition Protection Institute, Prague (Czech Republic)

    1996-12-31

    Monitoring of nuclear power plants (NPP) discharges into atmosphere and hydrosphere based on particulate-iodine-gas (PIG) measurements and gross beta and gamma plus tritium measurements respectively is being improved by nuclide specific measurements employing semiconductor gamma and alpha spectrometry and radiochemical methods. In connection with the progress new concept of authorized effluent limits and the related regulations is being implemented in the Czech Republic. Activities of all principally contributing to the effective dose radionuclides discharges during a year multiplied by a Sv/Bq conversion coefficient based on a standard model are summed up and the effective dose is compared with the new limit. These limits should be authorized for discharges into atmosphere as per caput collective committed effective dose in the NPP surrounding or as its value multiplied by the number of surrounding segment providing thus committed effective dose to member of a vital critical group and into the hydrosphere as committed effective dose to the critical group member. The criteria for obligatory evaluation of the specific radionuclide contribution and the resulting requirements on minimum detectable activities for both the shorter and longer monitoring intervals are included in the new regulations. The PIG and gross activity measurement results will be compared with investigation levels only and no more used for limitation purposes. (authors).

  5. THE NASA-UC ETA-EARTH PROGRAM. II. A PLANET ORBITING HD 156668 WITH A MINIMUM MASS OF FOUR EARTH MASSES

    International Nuclear Information System (INIS)

    Howard, Andrew W.; Marcy, Geoffrey W.; Isaacson, Howard; Johnson, John Asher; Fischer, Debra A.; Wright, Jason T.; Henry, Gregory W.; Valenti, Jeff A.; Anderson, Jay; Piskunov, Nikolai E.

    2011-01-01

    We report the discovery of HD 156668 b, an extrasolar planet with a minimum mass of M P sin i = 4.15 M + . This planet was discovered through Keplerian modeling of precise radial velocities from Keck-HIRES and is the second super-Earth to emerge from the NASA-UC Eta-Earth Survey. The best-fit orbit is consistent with circular and has a period of P = 4.6455 days. The Doppler semi-amplitude of this planet, K = 1.89 m s -1 , is among the lowest ever detected, on par with the detection of GJ 581 e using HARPS. A longer period (P ∼ 2.3 years), low-amplitude signal of unknown origin was also detected in the radial velocities and was filtered out of the data while fitting the short-period planet. Additional data are required to determine if the long-period signal is due to a second planet, stellar activity, or another source. Photometric observations using the Automated Photometric Telescopes at Fairborn Observatory show that HD 156668 (an old, quiet K3 dwarf) is photometrically constant over the radial velocity period to 0.1 mmag, supporting the existence of the planet. No transits were detected down to a photometric limit of ∼3 mmag, ruling out transiting planets dominated by extremely bloated atmospheres, but not precluding a transiting solid/liquid planet with a modest atmosphere.

  6. Analysis of background components in Ge-spectrometry and their influence on detection limits

    Energy Technology Data Exchange (ETDEWEB)

    Heusser, G [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany)

    1997-03-01

    In low radioactivity measurements the system own background of the spectrometer is, besides the counting efficiency, the limiting factor for the achievable sensitivity. Since the latter is mostly fixed, background reduction is the only way to gain sensitivity, although it is inversely proportional only to the square root of the background rate but directly proportional to the counting efficiency. A thorough understanding of the background sources and their quantitative contribution helps to choose the most adequate suppression method in order to reach a certain required level of detection limit. For Ge-spectrometry the background can be reduced by 5 to 6 orders of magnitude compared to the unshielded case applying state-of-the-art techniques. This reduction factor holds for the continuous background spectrum as well as for the line background as demonstrated for a Ge detector of the Heidelberg-Moscow double beta decay experiment. (orig./DG)

  7. Effects of intermediate load on performance limitations in excitation control

    Directory of Open Access Journals (Sweden)

    Pichai Aree

    2008-05-01

    Full Text Available The stability of excitation control systems is of great concern in power system operations. In this paper, the effects of intermediate load on performance limitation in excitation control are studied. The results reveal that the open-loop characteristic of synchronous machine’s flux linkage can be changed from minimum to non-minimum phase at a high level of intermediate load. This change leads to instability of synchronous machines under manual excitation control. A particular emphasis is also given to investigate the fundamental limitations in excitation control, imposed by non-minimum phases with regard to the open-loop right-half-plane (ORHP pole. The study demonstrates the difficulties of excitation control tuning to achieve the desired performance and robustness under the ORHP pole occurrence. Moreover, this paper shows the conditional stability in excitation control loop, where either an increase or decrease of the exciter gain causes a destabilization of the system’s stability. Frequency response techniques are used for these investigations.

  8. A minimum-size tokamak concept for conditions near ignition

    International Nuclear Information System (INIS)

    Lehnert, B.

    1983-01-01

    Based on a combination of Alcator scaling and a recent theory on the Murakami density limit, a minimum-size tokamak concept (Minitor) is proposed. Even if this concept does not aim at alpha particle containment, it has the important goal of reaching plasma core temperatures and Lawson parameter values required for ignition, by ohmic heating alone and under macroscopically stable conditions. The minimized size, and the associated enhancement of the plasma current density, are found to favour high plasma temperatues, average densities, and beta values. The goal of this concept appears to be realizable by relatively modest technical means. (author)

  9. 30 CFR 281.30 - Minimum royalty.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Minimum royalty. 281.30 Section 281.30 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE LEASING OF MINERALS OTHER THAN OIL, GAS, AND SULPHUR IN THE OUTER CONTINENTAL SHELF Financial Considerations § 281.30 Minimum royalty...

  10. WE-H-207A-09: Theoretical Limits to Molecular Biomarker Detection Using Magnetic Nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Weaver, J [Dartmouth-Hitchcock Medical Center, Lebanon, NH (United States); Geisel School of Medicine, Dartmouth College, Hanover, NH (United States)

    2016-06-15

    Purpose: Estimate the limits of molecular biomarker detection using magnetic nanoparticle methods like in vivo ELISA. Methods: Magnetic nanoparticles in an alternating magnetic field produce a magnetization that can be detected at exceedingly low levels because the signal at the harmonic frequencies is uniquely produced by the nanoparticles. Because the magnetization can also be used to characterize the nanoparticle rotational freedom, the bound state can be found. If the nanoparticles are coated with molecules that bind the desired biomarker, the rotational freedom reflects the biomarker concentration. The irreducible noise limit is the thermal noise or Johnson noise of the tissue and the contrast that can be measured must be larger than that limit. The contrast produced is a function of the applied field and depends strongly on nanoparticle volume. We have estimated the contrast using a Langevin function of a single composite variable to approximate the full stochastic Langevin equation for nanoparticle dynamics. Results: The thermal noise for a bandwidth reasonable for spectroscopy suggests mid zeptomolar (10–21) to low attomolar (10–18) concentrations can be measured in a volume that is 10cm in scale. The suggested sensitivity is far below the physiologically concentrations of almost all critical biomarkers including cytokines (picomolar), hormones (nanomolar) and heat shock proteins. Conclusion: The sensitivity of in vivo ELISA concentration measurements should be sufficient to measure physiological concentrations of critical biomarkers like cytokines in vivo. Further the sensitivity should be sufficient to measure concentrations of other biomarkers that are six to eight orders of magnitude lower in concentration than immune signaling molecules like cytokines. NIH - 1U54CA151662-01 Department of Radiology.

  11. State cigarette minimum price laws - United States, 2009.

    Science.gov (United States)

    2010-04-09

    Cigarette price increases reduce the demand for cigarettes and thereby reduce smoking prevalence, cigarette consumption, and youth initiation of smoking. Excise tax increases are the most effective government intervention to increase the price of cigarettes, but cigarette manufacturers use trade discounts, coupons, and other promotions to counteract the effects of these tax increases and appeal to price-sensitive smokers. State cigarette minimum price laws, initiated by states in the 1940s and 1950s to protect tobacco retailers from predatory business practices, typically require a minimum percentage markup to be added to the wholesale and/or retail price. If a statute prohibits trade discounts from the minimum price calculation, these laws have the potential to counteract discounting by cigarette manufacturers. To assess the status of cigarette minimum price laws in the United States, CDC surveyed state statutes and identified those states with minimum price laws in effect as of December 31, 2009. This report summarizes the results of that survey, which determined that 25 states had minimum price laws for cigarettes (median wholesale markup: 4.00%; median retail markup: 8.00%), and seven of those states also expressly prohibited the use of trade discounts in the minimum retail price calculation. Minimum price laws can help prevent trade discounting from eroding the positive effects of state excise tax increases and higher cigarette prices on public health.

  12. Optimization Strategies for Bruch's Membrane Opening Minimum Rim Area Calculation: Sequential versus Simultaneous Minimization.

    Science.gov (United States)

    Enders, Philip; Adler, Werner; Schaub, Friederike; Hermann, Manuel M; Diestelhorst, Michael; Dietlein, Thomas; Cursiefen, Claus; Heindl, Ludwig M

    2017-10-24

    To compare a simultaneously optimized continuous minimum rim surface parameter between Bruch's membrane opening (BMO) and the internal limiting membrane to the standard sequential minimization used for calculating the BMO minimum rim area in spectral domain optical coherence tomography (SD-OCT). In this case-control, cross-sectional study, 704 eyes of 445 participants underwent SD-OCT of the optic nerve head (ONH), visual field testing, and clinical examination. Globally and clock-hour sector-wise optimized BMO-based minimum rim area was calculated independently. Outcome parameters included BMO-globally optimized minimum rim area (BMO-gMRA) and sector-wise optimized BMO-minimum rim area (BMO-MRA). BMO area was 1.89 ± 0.05 mm 2 . Mean global BMO-MRA was 0.97 ± 0.34 mm 2 , mean global BMO-gMRA was 1.01 ± 0.36 mm 2 . Both parameters correlated with r = 0.995 (P < 0.001); mean difference was 0.04 mm 2 (P < 0.001). In all sectors, parameters differed by 3.0-4.2%. In receiver operating characteristics, the calculated area under the curve (AUC) to differentiate glaucoma was 0.873 for BMO-MRA, compared to 0.866 for BMO-gMRA (P = 0.004). Among ONH sectors, the temporal inferior location showed the highest AUC. Optimization strategies to calculate BMO-based minimum rim area led to significantly different results. Imposing an additional adjacency constraint within calculation of BMO-MRA does not improve diagnostic power. Global and temporal inferior BMO-MRA performed best in differentiating glaucoma patients.

  13. Fluctuation Scaling, Calibration of Dispersion, and Detection of Differences.

    Science.gov (United States)

    Holland, Rianne; Rebmann, Roman; Williams, Craig; Hanley, Quentin S

    2017-11-07

    Fluctuation scaling describes the relationship between the mean and standard deviation of a set of measurements. An example is Horwitz scaling, which has been reported from interlaboratory studies. Horwitz and similar studies have reported simple exponential and segmented scaling laws with exponents (α) typically between 0.85 (Horwitz) and 1 when not operating near a detection limit. When approaching a detection limit, the exponents change and approach an apparently Gaussian (α = 0) model. This behavior is often presented as a property of interlaboratory studies, which makes controlled replication to understand the behavior costly to perform. To assess the contribution of instrumentation to larger scale fluctuation scaling, we measured the behavior of two inductively coupled plasma atomic emission spectrometry (ICP-AES) systems, in two laboratories measuring thulium using two emission lines. The standard deviation universally increased with the uncalibrated signal, indicating the system was heteroscedastic. The response from all lines and both instruments was consistent with a single exponential dispersion model having parameters α = 1.09 and β = 0.0035. No evidence of Horwitz scaling was found, and there was no evidence of Poisson noise limiting behavior. The "Gaussian" component was a consequence of background subtraction for all lines and both instruments. The observation of a simple exponential dispersion model in the data allows for the definition of a difference detection limit (DDL) with universal applicability to systems following known dispersion. The DDL is the minimum separation between two points along a dispersion model required to claim they are different according to a particular statistical test. The DDL scales transparently with the mean and works at any location in a response function.

  14. Lower detectable limit of sulfur by fast neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Shani, G; Cohen, D [Ben-Gurion Univ. of the Negev, Beersheba (Israel). Dept. of Nuclear Engineering

    1976-07-01

    For the purpose of air pollution research, the possibility of fast neutron activation analysis of sulfur was investigated. The only reaction that can be used for this purpose is S/sup 34/(n, p)P/sup 34/. A rabbit system was installed, synchronized with a 150 kV D-T neutron generator and an electronic analysing system. The whole system was operated so that the sample was irradiated for 10 sec and the 2.13 MeV ..gamma..-ray was counted for 10 sec. 5 samples were prepared containing sulfur from 0.5 to 0.1 g. Each measurement lasted 30 min and the activity was plotted as a function of sulfur weight. The relative error is increased very much when the amount of sulfur is below 0.1 g. This is what sets the lower detectable limit. Collection of more than 0.1 g of sulfur even during a long collection time means a very high SO/sub 2/ concentration in the air.

  15. Evaluation of MidIR fibre optic reflectance: Detection limit, reproducibility and binary mixture discrimination

    Science.gov (United States)

    Sessa, Clarimma; Bagán, Héctor; García, José Francisco

    2013-11-01

    MidIR fibre optic reflectance (MidIR-FORS) is a promising analytical technique in the field of science conservation, especially because it is non-destructive. Another advantage of MidIR-FORS is that the obtained information is representative, as a large amount of spectral data can be collected. Although the technique has a high potential and is almost routinely applied, its quality parameters have not been thoroughly studied in the specific application of analysis of artistic materials. The objective of this study is to evaluate the instrumental capabilities of MidIR-FORS for the analysis of artwork materials in terms of detection limit, reproducibility, and mixture characterisation. The study has been focused on oil easel painting and several paints of known composition have been analysed. Paint layers include blue pigments not only because of their important role along art history, but also because their physical and spectroscopic characteristics allow a better evaluation of the MidIR-FORS capabilities. The results of the analysis indicate that MidIR-FORS supplies a signal affected by different factors, such as the optical, morphological and physical properties of the surface, in addition to the composition of materials analysed. Consequently, the detection limits established are relatively high for artistic objects (Prussian blue - PB 2.1-6.5%; Phthalocyanine blue - Pht 6.3-10.2%; synthetic Ultramarine blue - UM 12.1%) and may therefore lead to an incomplete description of the artwork. Reproducibility of the technique over time and across surface has been determined. The results show that the major sources of dispersion are the heterogeneity of the pigments distribution, physical features, and band shape distortions. The total dispersion is around 4% for the most intense bands (oil) and increases up to 26% when weak or overlapped bands are considered (PB, Pht, UM). The application of different pre-treatments (cutoff of fibres absorption, Savizky-Golay smoothing

  16. Intracavity Faraday modulation spectroscopy (INFAMOS): A tool for radical detection

    Science.gov (United States)

    Gianella, Michele; Pinto, Tomas H. P.; Wu, Xia; Ritchie, Grant A. D.

    2017-08-01

    We present the intra-cavity Faraday modulation spectroscopy technique, whereby optical feedback cavity-enhanced spectroscopy is coupled with Faraday modulation spectroscopy to greatly enhance the interaction path length of a laser beam with a paramagnetic sample in a magnetic field. We describe a first prototype based upon a cw quantum cascade laser targeting a selection of fundamental rovibrational R-branch transitions of nitric oxide (1890 cm-1), consisting of a linear cavity (finesse F =6300 ) and a water-cooled solenoid. We demonstrate a minimum detectable Verdet constant of Vmin=4.7 ×10-14 rad cm-1 G-1 H z-1/2 (at SNR = 1), corresponding to a single-pass rotation angle of 1.6 ×10-10 rad Hz-1/2 and a limit of detection of 0.21 ppbv Hz-1/2 NO.

  17. Intracavity Faraday modulation spectroscopy (INFAMOS): A tool for radical detection.

    Science.gov (United States)

    Gianella, Michele; Pinto, Tomas H P; Wu, Xia; Ritchie, Grant A D

    2017-08-07

    We present the intra-cavity Faraday modulation spectroscopy technique, whereby optical feedback cavity-enhanced spectroscopy is coupled with Faraday modulation spectroscopy to greatly enhance the interaction path length of a laser beam with a paramagnetic sample in a magnetic field. We describe a first prototype based upon a cw quantum cascade laser targeting a selection of fundamental rovibrational R-branch transitions of nitric oxide (1890 cm -1 ), consisting of a linear cavity (finesse F=6300) and a water-cooled solenoid. We demonstrate a minimum detectable Verdet constant of V min =4.7×10 -14  rad cm -1  G -1  Hz -1/2 (at SNR = 1), corresponding to a single-pass rotation angle of 1.6×10 -10  rad Hz -1/2 and a limit of detection of 0.21 ppbv Hz -1/2 NO.

  18. Investigation of detection limits for diffuse optical tomography systems: II. Analysis of slab and cup geometry for breast imaging.

    Science.gov (United States)

    Ziegler, Ronny; Brendel, Bernhard; Rinneberg, Herbert; Nielsen, Tim

    2009-01-21

    Using a statistical (chi-square) test on simulated data and a realistic noise model derived from the system's hardware we study the performance of diffuse optical tomography systems for fluorescence imaging. We compare the predicted smallest size of detectable lesions at various positions in slab and cup geometry and model how detection sensitivity depends on breast compression and lesion fluorescence contrast. Our investigation shows that lesion detection is limited by relative noise in slab geometry and by absolute noise in cup geometry.

  19. 9 CFR 147.51 - Authorized laboratory minimum requirements.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Authorized laboratory minimum requirements. 147.51 Section 147.51 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... Authorized Laboratories and Approved Tests § 147.51 Authorized laboratory minimum requirements. These minimum...

  20. Robustification and Optimization in Repetitive Control For Minimum Phase and Non-Minimum Phase Systems

    Science.gov (United States)

    Prasitmeeboon, Pitcha

    repetitive control FIR compensator. The aim is to reduce the final error level by using real time frequency response model updates to successively increase the cutoff frequency, each time creating the improved model needed to produce convergence zero error up to the higher cutoff. Non-minimum phase systems present a difficult design challenge to the sister field of Iterative Learning Control. The third topic investigates to what extent the same challenges appear in RC. One challenge is that the intrinsic non-minimum phase zero mapped from continuous time is close to the pole of repetitive controller at +1 creating behavior similar to pole-zero cancellation. The near pole-zero cancellation causes slow learning at DC and low frequencies. The Min-Max cost function over the learning rate is presented. The Min-Max can be reformulated as a Quadratically Constrained Linear Programming problem. This approach is shown to be an RC design approach that addresses the main challenge of non-minimum phase systems to have a reasonable learning rate at DC. Although it was illustrated that using the Min-Max objective improves learning at DC and low frequencies compared to other designs, the method requires model accuracy at high frequencies. In the real world, models usually have error at high frequencies. The fourth topic addresses how one can merge the quadratic penalty to the Min-Max cost function to increase robustness at high frequencies. The topic also considers limiting the Min-Max optimization to some frequencies interval and applying an FIR zero-phase low-pass filter to cutoff the learning for frequencies above that interval.

  1. Experimental investigations of the minimum ignition energy and the minimum ignition temperature of inert and combustible dust cloud mixtures.

    Science.gov (United States)

    Addai, Emmanuel Kwasi; Gabel, Dieter; Krause, Ulrich

    2016-04-15

    The risks associated with dust explosions still exist in industries that either process or handle combustible dust. This explosion risk could be prevented or mitigated by applying the principle of inherent safety (moderation). This is achieved by adding an inert material to a highly combustible material in order to decrease the ignition sensitivity of the combustible dust. The presented paper deals with the experimental investigation of the influence of adding an inert dust on the minimum ignition energy and the minimum ignition temperature of the combustible/inert dust mixtures. The experimental investigation was done in two laboratory scale equipment: the Hartmann apparatus and the Godbert-Greenwald furnace for the minimum ignition energy and the minimum ignition temperature test respectively. This was achieved by mixing various amounts of three inert materials (magnesium oxide, ammonium sulphate and sand) and six combustible dusts (brown coal, lycopodium, toner, niacin, corn starch and high density polyethylene). Generally, increasing the inert materials concentration increases the minimum ignition energy as well as the minimum ignition temperatures until a threshold is reached where no ignition was obtained. The permissible range for the inert mixture to minimize the ignition risk lies between 60 to 80%. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. Underage drinking: does the minimum age drinking law offer enough protection?

    Science.gov (United States)

    Green, Rivka; Jason, Hannah; Ganz, Debora

    2015-05-01

    Underage drinking is a significant problem in the US. It is responsible for several thousand mortalities and fatalities each year, both among minors and other members of society. Additionally, underage alcohol consumption produces a severe economic burden in the US. Introduction to alcohol in youth poses serious long-term risks for adolescents, including occupational, educational, and psychosocial impairments, and increases the risk for developing alcohol abuse disorders in adulthood. In order to address and mitigate this problem, the US has set a minimum age drinking law of 21 in all 50 states, and has implemented several supplementary laws limiting the possession and consumption of alcohol. Though these laws have successfully reduced underage drinking, several additional strategies are noteworthy, including preventative and intervention efforts incorporating environmental, individual, communal, and parental factors. The following literature review describes these concepts as they relate to underage drinking laws in the US. Directions for future research, interventions, and ongoing challenges related to the minimum drinking age in the US are also discussed.

  3. Minimum beam-energy spread of a high-current rf linac

    International Nuclear Information System (INIS)

    Chan, K.C.D.; Fraser, J.S.

    1987-01-01

    Energy spread is an important parameter of an electron linac and, usually, is determined by the time dependence of the external rf accelerating field. By using a combination of fundamental and higher harmonic frequencies, the accelerating field can be maintained approximately constant over a beam bunch with the resultant energy spread approximately zero. This technique is no longer adequate when the longitudinal wake field of the beam bunch is taken into account. The wake-field variation along the bunch length introduces an energy spread that cannot be exactly compensated for with the use of fundamental and higher harmonic frequencies. The achievable minimum energy spread including the wake-field effect is therefore limited. In this paper, we report the minimum energy spreads achievable using the fundamental and third-harmonic frequencies, calculated using a least-squares algorithm, for some typical structures in use at Los Alamos National Laboratory. The dependence of these results on bunch shape, bunch charge, and structure frequency is discussed. Also included are discussions of schemes for implementing the third-harmonic frequency and their effectiveness

  4. Minimum Price Guarantees In a Consumer Search Model

    NARCIS (Netherlands)

    M.C.W. Janssen (Maarten); A. Parakhonyak (Alexei)

    2009-01-01

    textabstractThis paper is the first to examine the effect of minimum price guarantees in a sequential search model. Minimum price guarantees are not advertised and only known to consumers when they come to the shop. We show that in such an environment, minimum price guarantees increase the value of

  5. Limit of detection of a fiber optics gyroscope using a super luminescent radiation source

    International Nuclear Information System (INIS)

    Sandoval R, G.E.; Nikolaev, V.A.

    2003-01-01

    The main objective of this work is to establish the dependence of characteristics of the fiber optics gyroscope (FOG) with respect to the parameters of the super luminescent emission source based on doped optical fiber with rare earth elements (Super luminescent Fiber Source, SFS), argument the pumping rate election of the SFS to obtain characteristics limits of the FOG sensibility. By using this type of emission source in the FOG is recommend to use the rate when the direction of the pumping signal coincide with the super luminescent signal. The most results are the proposition and argumentation of the SFS election as emission source to be use in the FOG of the phase type. Such a decision allow to increase the characteristics of the FOG sensibility in comparison with the use of luminescent source of semiconductors emission which are extensively used in the present time. The use of emission source of the SFS type allow to come closer to the threshold of the obtained sensibility limit (detection limit) which is determined with the shot noise. (Author)

  6. Limit of detection of a fiber optics gyroscope using a super luminescent radiation source

    CERN Document Server

    Sandoval, G E

    2003-01-01

    The main objective of this work is to establish the dependence of characteristics of the fiber optics gyroscope (FOG) with respect to the parameters of the super luminescent emission source based on doped optical fiber with rare earth elements (Super luminescent Fiber Source, SFS), argument the pumping rate election of the SFS to obtain characteristics limits of the FOG sensibility. By using this type of emission source in the FOG is recommend to use the rate when the direction of the pumping signal coincide with the super luminescent signal. The most results are the proposition and argumentation of the SFS election as emission source to be use in the FOG of the phase type. Such a decision allow to increase the characteristics of the FOG sensibility in comparison with the use of luminescent source of semiconductors emission which are extensively used in the present time. The use of emission source of the SFS type allow to come closer to the threshold of the obtained sensibility limit (detection limit) which i...

  7. Ultrasensitive leak detection

    International Nuclear Information System (INIS)

    Winkelman, C.R.; Davidson, H.G.

    1978-01-01

    The objective of this investigation was to develop a method of detecting leaks to a sensitivity of 1.0 x 10 -13 std/cm 3 /s in vacuum devices and to develop a qualifiable standard leak to provide system calibration at this leak rate. The development work demonstrated that minimum detectable leak rates of 6.5 x 10 -14 std/cm 3 /s and 5.5 x 10 -15 std/cm 3 /s are possible for respective analog and digital measurement modes

  8. Radioactivity analyses and detection limit problems of environmental surveillance at a gas-cooled reactor

    International Nuclear Information System (INIS)

    Johnson, J.E.; Johnson, J.A.

    1988-01-01

    The lower limit of detection (LLD) values required by the USNRC for nuclear power facilities are often difficult to attain even using state of the art detection systems, e.g. the required LLD for I-131 in air is 70 fCi/m 3 . For a gas-cooled reactor where I-131 has never been observed in effluents, occasional false positive values occur due to: Counting statistics using high resolution Ge(Li) detectors, contamination from nuclear medicine releases and spectrum analysis systematic error. Statistically negative concentration values are often observed. These measurements must be included in the estimation of true mean values. For this and other reasons, the frequency distributions of this and other reasons, the frequency distributions of measured values appear to be log-normal. Difficulties in stating the true means and standard deviations are discussed for these situations

  9. Limited copy number-high resolution melting (LCN-HRM) enables the detection and identification by sequencing of low level mutations in cancer biopsies.

    Science.gov (United States)

    Do, Hongdo; Dobrovic, Alexander

    2009-10-08

    Mutation detection in clinical tumour samples is challenging when the proportion of tumour cells, and thus mutant alleles, is low. The limited sensitivity of conventional sequencing necessitates the adoption of more sensitive approaches. High resolution melting (HRM) is more sensitive than sequencing but identification of the mutation is desirable, particularly when it is important to discriminate false positives due to PCR errors or template degradation from true mutations.We thus developed limited copy number - high resolution melting (LCN-HRM) which applies limiting dilution to HRM. Multiple replicate reactions with a limited number of target sequences per reaction allow low level mutations to be detected. The dilutions used (based on Ct values) are chosen such that mutations, if present, can be detected by the direct sequencing of amplicons with aberrant melting patterns. Using cell lines heterozygous for mutations, we found that the mutations were not readily detected when they comprised 10% of total alleles (20% tumour cells) by sequencing, whereas they were readily detectable at 5% total alleles by standard HRM. LCN-HRM allowed these mutations to be identified by direct sequencing of those positive reactions.LCN-HRM was then used to review formalin-fixed paraffin-embedded (FFPE) clinical samples showing discordant findings between sequencing and HRM for KRAS exon 2 and EGFR exons 19 and 21. Both true mutations present at low levels and sequence changes due to artefacts were detected by LCN-HRM. The use of high fidelity polymerases showed that the majority of the artefacts were derived from the damaged template rather than replication errors during amplification. LCN-HRM bridges the sensitivity gap between HRM and sequencing and is effective in distinguishing between artefacts and true mutations.

  10. Assessing Seasonal and Inter-Annual Variations of Lake Surface Areas in Mongolia during 2000-2011 Using Minimum Composite MODIS NDVI.

    Science.gov (United States)

    Kang, Sinkyu; Hong, Suk Young

    2016-01-01

    A minimum composite method was applied to produce a 15-day interval normalized difference vegetation index (NDVI) dataset from Moderate Resolution Imaging Spectroradiometer (MODIS) daily 250 m reflectance in the red and near-infrared bands. This dataset was applied to determine lake surface areas in Mongolia. A total of 73 lakes greater than 6.25 km2in area were selected, and 28 of these lakes were used to evaluate detection errors. The minimum composite NDVI showed a better detection performance on lake water pixels than did the official MODIS 16-day 250 m NDVI based on a maximum composite method. The overall lake area detection performance based on the 15-day minimum composite NDVI showed -2.5% error relative to the Landsat-derived lake area for the 28 evaluated lakes. The errors increased with increases in the perimeter-to-area ratio but decreased with lake size over 10 km(2). The lake area decreased by -9.3% at an annual rate of -53.7 km(2) yr(-1) during 2000 to 2011 for the 73 lakes. However, considerable spatial variations, such as slight-to-moderate lake area reductions in semi-arid regions and rapid lake area reductions in arid regions, were also detected. This study demonstrated applicability of MODIS 250 m reflectance data for biweekly monitoring of lake area change and diagnosed considerable lake area reduction and its spatial variability in arid and semi-arid regions of Mongolia. Future studies are required for explaining reasons of lake area changes and their spatial variability.

  11. Wage inequality, minimum wage effects and spillovers

    OpenAIRE

    Stewart, Mark B.

    2011-01-01

    This paper investigates possible spillover effects of the UK minimum wage. The halt in the growth in inequality in the lower half of the wage distribution (as measured by the 50:10 percentile ratio) since the mid-1990s, in contrast to the continued inequality growth in the upper half of the distribution, suggests the possibility of a minimum wage effect and spillover effects on wages above the minimum. This paper analyses individual wage changes, using both a difference-in-differences estimat...

  12. Improvement in operational characteristics of KEPCO’s line-commutation-type superconducting hybrid fault current limiter

    International Nuclear Information System (INIS)

    Yim, S.-W.; Park, B.-C.; Jeong, Y.-T.; Kim, Y.-J.; Yang, S.-E.; Kim, W.-S.; Kim, H.-R.; Du, H.-I.

    2013-01-01

    Highlights: ► A line-commutation type hybrid FCL was modified for 1st peak current limitation. ► A superconducting module of current limitation and fault detection was fabricated. ► The superconducting module was applied to a hybrid FCL system and tested. ► 7.4 kA p fault current was limited to 4.3 kA p at the first-half cycle by the FCL. -- Abstract: A 22.9 kV class hybrid fault current limiter (FCL) developed by Korea Electric Power Corporation and LS Industrial Systems in 2006 operates using the line commutation mechanism and begins to limit the fault current after the first half-cycle. The first peak of the fault current is available for protective coordination in the power system. However, it also produces a large electromagnetic force and imposes a huge stress on power facilities such as the main transformer and gas-insulated switchgear. In this study, we improved the operational characteristics of the hybrid FCL in order to reduce the first peak of the fault current. While maintaining the structure of the hybrid FCL system, we developed a superconducting module that detects and limits the fault current during the first half-cycle. To maintain the protective coordination capacity, the hybrid FCL was designed to reduce the first peak value of the fault current by up to approximately 30%. The superconducting module was also designed to produce a minimum AC loss, generating a small, uniform magnetic field distribution during normal operation. Performance tests confirmed that when applied to the hybrid FCL, the superconducting module showed successful current limiting operation without any damage

  13. Application and Limitations of GPS Radio Occultation (GPS-RO) Data for Atmospheric Boundary Layer Height Detection over the Arctic.

    Science.gov (United States)

    Ganeshan, M.; Wu, D. L.

    2014-12-01

    Due to recent changes in the Arctic environment, it is important to monitor the atmospheric boundary layer (ABL) properties over the Arctic Ocean, especially to explore the variability in ABL clouds (such as sensitivity and feedback to sea ice loss). For example, radiosonde and satellite observations of the Arctic ABL height (and low-cloud cover) have recently suggested a positive response to sea ice loss during October that may not occur during the melt season (June-September). Owing to its high vertical and spatiotemporal resolution, an independent ABL height detection algorithm using GPS Radio Occultation (GPS-RO) refractivity in the Arctic is explored. Similar GPS-RO algorithms developed previously typically define the level of the most negative moisture gradient as the ABL height. This definition is favorable for subtropical oceans where a stratocumulus-topped ABL is often capped by a layer of sharp moisture lapse rate (coincident with the temperature inversion). The Arctic Ocean is also characterized by stratocumulus cloud cover, however, the specific humidity does not frequently decrease in the ABL capping inversion. The use of GPS-RO refractivity for ABL height retrieval therefore becomes more complex. During winter months (December-February), when the total precipitable water in the troposphere is a minimum, a fairly straightforward algorithm for ABL height retrieval is developed. The applicability and limitations of this method for other seasons (Spring, Summer, Fall) is determined. The seasonal, interannual and spatial variability in the GPS-derived ABL height over the Arctic Ocean, as well as its relation to the underlying surface (ice vs. water), is investigated. The GPS-RO profiles are also explored for the evidence of low-level moisture transport in the cold Arctic environment.

  14. Minimum Variance Portfolios in the Brazilian Equity Market

    Directory of Open Access Journals (Sweden)

    Alexandre Rubesam

    2013-03-01

    Full Text Available We investigate minimum variance portfolios in the Brazilian equity market using different methods to estimate the covariance matrix, from the simple model of using the sample covariance to multivariate GARCH models. We compare the performance of the minimum variance portfolios to those of the following benchmarks: (i the IBOVESPA equity index, (ii an equally-weighted portfolio, (iii the maximum Sharpe ratio portfolio and (iv the maximum growth portfolio. Our results show that the minimum variance portfolio has higher returns with lower risk compared to the benchmarks. We also consider long-short 130/30 minimum variance portfolios and obtain similar results. The minimum variance portfolio invests in relatively few stocks with low βs measured with respect to the IBOVESPA index, being easily replicable by individual and institutional investors alike.

  15. Network single-walled carbon nanotube biosensors for fast and highly sensitive detection of proteins

    International Nuclear Information System (INIS)

    Hu Pingan; Zhang Jia; Wen Zhenzhong; Zhang Can

    2011-01-01

    Detection of proteins is powerfully assayed in the diagnosis of diseases. A strategy for the development of an ultrahigh sensitivity biosensor based on a network single-walled carbon nanotube (SWNT) field-effect transistor (FET) has been demonstrated. Metallic SWNTs (m-SWNTs) in the network nanotube FET were selectively removed or cut via a carefully controlled procedure of electrical break-down (BD), and left non-conducting m-SWNTs which magnified the Schottky barrier (SB) area. This nanotube FET exhibited ultrahigh sensitivity and fast response to biomolecules. The lowest detection limit of 0.5 pM was achieved by exploiting streptavidin (SA) or a biotin/SA pair as the research model, and BD-treated nanotube biosensors had a 2 x 10 4 -fold lower minimum detectable concentration than the device without BD treatment. The response time is in the range of 0.3-3 min.

  16. Choice of filters for the detection of gravitational waves from coalescing binaries 2: Detection in coloured noise

    International Nuclear Information System (INIS)

    Dhurandhar, S.V.; Sathyaprakash, B.S.

    1992-10-01

    We discuss the problem of detecting gravitational wave signals embedded in coloured noise from coalescing binary systems. The signal is assumed to be Newtonian and matched filtering techniques are employed to filter out the signal. The problem is discussed at first for a general power spectral density of the noise and then specific numerical results are obtained for the standard recycling case. Since the signal parameters are unknown, a bank of filters is needed to carry out the signal detection. The number of filters in a bank, the spacing between filters etc. is obtained for different values of the minimum strength of the signal relative to the threshold. We also present an approximate analytical formula which relates the spacing between filters to the minimum strength. Finally, we discuss the problem of detection probabilities given a data train. (author). 21 refs, 2 figs, 3 tabs

  17. Minimum Time Search in Uncertain Dynamic Domains with Complex Sensorial Platforms

    Science.gov (United States)

    Lanillos, Pablo; Besada-Portas, Eva; Lopez-Orozco, Jose Antonio; de la Cruz, Jesus Manuel

    2014-01-01

    The minimum time search in uncertain domains is a searching task, which appears in real world problems such as natural disasters and sea rescue operations, where a target has to be found, as soon as possible, by a set of sensor-equipped searchers. The automation of this task, where the time to detect the target is critical, can be achieved by new probabilistic techniques that directly minimize the Expected Time (ET) to detect a dynamic target using the observation probability models and actual observations collected by the sensors on board the searchers. The selected technique, described in algorithmic form in this paper for completeness, has only been previously partially tested with an ideal binary detection model, in spite of being designed to deal with complex non-linear/non-differential sensorial models. This paper covers the gap, testing its performance and applicability over different searching tasks with searchers equipped with different complex sensors. The sensorial models under test vary from stepped detection probabilities to continuous/discontinuous differentiable/non-differentiable detection probabilities dependent on distance, orientation, and structured maps. The analysis of the simulated results of several static and dynamic scenarios performed in this paper validates the applicability of the technique with different types of sensor models. PMID:25093345

  18. Minimum Covers of Fixed Cardinality in Weighted Graphs.

    Science.gov (United States)

    White, Lee J.

    Reported is the result of research on combinatorial and algorithmic techniques for information processing. A method is discussed for obtaining minimum covers of specified cardinality from a given weighted graph. By the indicated method, it is shown that the family of minimum covers of varying cardinality is related to the minimum spanning tree of…

  19. Determining the 95% limit of detection for waterborne pathogen analyses from primary concentration to qPCR

    Science.gov (United States)

    Stokdyk, Joel P.; Firnstahl, Aaron; Spencer, Susan K.; Burch, Tucker R; Borchardt, Mark A.

    2016-01-01

    The limit of detection (LOD) for qPCR-based analyses is not consistently defined or determined in studies on waterborne pathogens. Moreover, the LODs reported often reflect the qPCR assay alone rather than the entire sample process. Our objective was to develop an approach to determine the 95% LOD (lowest concentration at which 95% of positive samples are detected) for the entire process of waterborne pathogen detection. We began by spiking the lowest concentration that was consistently positive at the qPCR step (based on its standard curve) into each procedural step working backwards (i.e., extraction, secondary concentration, primary concentration), which established a concentration that was detectable following losses of the pathogen from processing. Using the fraction of positive replicates (n = 10) at this concentration, we selected and analyzed a second, and then third, concentration. If the fraction of positive replicates equaled 1 or 0 for two concentrations, we selected another. We calculated the LOD using probit analysis. To demonstrate our approach we determined the 95% LOD for Salmonella enterica serovar Typhimurium, adenovirus 41, and vaccine-derived poliovirus Sabin 3, which were 11, 12, and 6 genomic copies (gc) per reaction (rxn), respectively (equivalent to 1.3, 1.5, and 4.0 gc L−1 assuming the 1500 L tap-water sample volume prescribed in EPA Method 1615). This approach limited the number of analyses required and was amenable to testing multiple genetic targets simultaneously (i.e., spiking a single sample with multiple microorganisms). An LOD determined this way can facilitate study design, guide the number of required technical replicates, aid method evaluation, and inform data interpretation.

  20. 49 CFR 192.229 - Limitations on welders.

    Science.gov (United States)

    2010-10-01

    ... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Welding of Steel in Pipelines § 192.229 Limitations on welders. (a) No welder whose qualification is based on nondestructive testing may weld compressor station pipe and components. (b) No welder may weld with a particular welding process unless, within the...

  1. Detection of land mines by amplified fluorescence quenching of polymer films: a man-portable chemical sniffer for detection of ultratrace concentrations of explosives emanating from land mines

    Science.gov (United States)

    la Grone, Marcus J.; Cumming, Colin J.; Fisher, Mark E.; Fox, Michael J.; Jacob, Sheena; Reust, Dennis; Rockley, Mark G.; Towers, Eric

    2000-08-01

    The explosive charge within a landmine is the source for a mixture of chemical vapors that form a distinctive 'chemical signature' indicative of a landmine. The concentration of these compounds in the air over landmines is extremely low, well below the minimum detection limits of most field- portable chemical sensors. Described in this paper is a man- portable landmine detection system that has for the first time demonstrated the ability to detect landmines by direct sensing of the vapors of signature compounds in the air over landmines. The system utilizes fluorescent polymers developed by collaborators at the MIT. The sensor can detect ultra-trace concentrations of TNT vapor and other nitroaromatic compounds found in many landmine explosives. Thin films of the polymers exhibit intense fluorescence, but when exposed to vapors of nitroaromatic explosives the intensity of the light emitted from the films decreases. A single molecule of TNT binding to a receptor site quenches the fluorescence from many polymer repeat units, increasing the sensitivity by orders of magnitude. A sensor prototype has been develop that response in near real-time to low femtogram quantities of nitroaromatic explosives. The prototype is portable, lightweight, has low power consumption, is simple to operate, and is relatively inexpensive. Simultaneous field testing of the sensor and experienced canine landmine detection teams was recently completed. Although the testing was limited in scope, the performance of the senor met or exceeded that of the canines against buried landmines.

  2. Digitizing Tablet and Fahn–Tolosa–Marín Ratings of Archimedes Spirals have Comparable Minimum Detectable Change in Essential Tremor

    Directory of Open Access Journals (Sweden)

    Rodger J. Elble

    2017-07-01

    Full Text Available Background: Drawing Archimedes spirals is a popular and valid method of assessing action tremor in the upper limbs. We performed the first blinded comparison of Fahn–Tolosa–Marín (FTM ratings and tablet measures of essential tremor to determine if a digitizing tablet is better than 0–4 ratings in detecting changes in essential tremor that exceed random variability in tremor amplitude.Methods: The large and small spirals of FTM were drawn with each hand on two consecutive days by 14 men and four women (age 60±8.7 years [mean±SD] with mild to severe essential tremor. The drawings were simultaneously digitized with a digitizing tablet. Tremor in each digitized drawing was computed with spectral analysis in an independent laboratory, blinded to the clinical ratings. The mean peak-to-peak tremor displacement (cm in the four spirals and mean FTM ratings were compared statistically.Results: Test–retest intraclass correlations (ICCs (two-way random single measures, absolute agreement were excellent for the FTM ratings (ICC 0.90, 95% CI 0.76–0.96 and tablet (ICC 0.97, 95% CI 0.91–0.99. Log10 tremor amplitude (T and FTM were strongly correlated (logT = αFTM + β, α≈0.6, β≈–1.27, r = 0.94. The minimum detectable change for the tablet and FTM were 51% and 67% of the initial assessment.Discussion: Digitizing tablets are much more precise than clinical ratings, but this advantage is mitigated by the natural variability in tremor. Nevertheless, the digitizing tablet is a robust method of quantifying tremor that can be used in lieu of or in combination with clinical ratings.

  3. Vertical and horizontal extension of the oxygen minimum zone in the eastern South Pacific Ocean

    Science.gov (United States)

    Fuenzalida, Rosalino; Schneider, Wolfgang; Garcés-Vargas, José; Bravo, Luis; Lange, Carina

    2009-07-01

    Recent hydrographic measurements within the eastern South Pacific (1999-2001) were combined with vertically high-resolution data from the World Ocean Circulation Experiment, high-resolution profiles and bottle casts from the World Ocean Database 2001, and the World Ocean Atlas 2001 in order to evaluate the vertical and horizontal extension of the oxygen minimum zone (oxygen minimum zone to be 9.82±3.60×10 6 km 2 and 2.18±0.66×10 6 km 3, respectively. The oxygen minimum zone is thickest (>600 m) off Peru between 5 and 13°S and to about 1000 km offshore. Its upper boundary is shallowest (zone in some places. Offshore, the thickness and meridional extent of the oxygen minimum zone decrease until it finally vanishes at 140°W between 2° and 8°S. Moving southward along the coast of South America, the zonal extension of the oxygen minimum zone gradually diminishes from 3000 km (15°S) to 1200 km (20°S) and then to 25 km (30°S); only a thin band is detected at ˜37°S off Concepción, Chile. Simultaneously, the oxygen minimum zone's maximum thickness decreases from 300 m (20°S) to less than 50 m (south of 30°S). The spatial distribution of Ekman suction velocity and oxygen minimum zone thickness correlate well, especially in the core. Off Chile, the eastern South Pacific Intermediate Water mass introduces increased vertical stability into the upper water column, complicating ventilation of the oxygen minimum zone from above. In addition, oxygen-enriched Antarctic Intermediate Water clashes with the oxygen minimum zone at around 30°S, causing a pronounced sub-surface oxygen front. The new estimates of vertical and horizontal oxygen minimum zone distribution in the eastern South Pacific complement the global quantification of naturally hypoxic continental margins by Helly and Levin [2004. Global distribution of naturally occurring marine hypoxia on continental margins. Deep-Sea Research I 51, 1159-1168] and provide new baseline data useful for studies on the

  4. Uncertainty and minimum detectable concentrations using relative, absolute and K*0-IAEA standardization for the INAA laboratory of the ETRR-2

    International Nuclear Information System (INIS)

    Khalil, M. Y.

    2006-01-01

    Full text: The Instrumental Neutron Activation Analysis (INAA) Laboratory of Egypt Second Training and Research Reactor (ETRR-2) is increasingly requested to perform multi-element analysis to large number of samples from different origins. The INAA laboratory has to demonstrate competence by conforming to appropriate internationally and nationally accepted standards. The objective of this work is to determine the uncertainty budget and sensitivity of the INAA laboratory measurements. Concentrations of 9 elements; Mn, Na, K, Ca, Co, Cr, Fe, Rb, and Cs, were measured against a certified test sample. Relative, absolute, and Ko-IAEA standardization methods were employed and results compared. The flux was monitored using cadmium covered gold method, and multifoil (gold, nickel and zirconium) method. The combined and expanded uncertainties were estimated. Uncertainty of concentrations ranged between 2-21% depending on the standardization method used. The relative method, giving the lowest uncertainty, produced uncertainty budget between 2 and 11%. The minimum detectable concentration was the lowest for Cs ranging between 0.36 and 0.59 ppb and the highest being for K in the range of 0.32 to 8.64 ppm

  5. Who Benefits from a Minimum Wage Increase?

    OpenAIRE

    John W. Lopresti; Kevin J. Mumford

    2015-01-01

    This paper addresses the question of how a minimum wage increase affects the wages of low-wage workers. Most studies assume that there is a simple mechanical increase in the wage for workers earning a wage between the old and the new minimum wage, with some studies allowing for spillovers to workers with wages just above this range. Rather than assume that the wages of these workers would have remained constant, this paper estimates how a minimum wage increase impacts a low-wage worker's wage...

  6. The minimum wage in the Czech enterprises

    Directory of Open Access Journals (Sweden)

    Eva Lajtkepová

    2010-01-01

    Full Text Available Although the statutory minimum wage is not a new category, in the Czech Republic we encounter the definition and regulation of a minimum wage for the first time in the 1990 amendment to Act No. 65/1965 Coll., the Labour Code. The specific amount of the minimum wage and the conditions of its operation were then subsequently determined by government regulation in February 1991. Since that time, the value of minimum wage has been adjusted fifteenth times (the last increase was in January 2007. The aim of this article is to present selected results of two researches of acceptance of the statutory minimum wage by Czech enterprises. The first research makes use of the data collected by questionnaire research in 83 small and medium-sized enterprises in the South Moravia Region in 2005, the second one the data of 116 enterprises in the entire Czech Republic (in 2007. The data have been processed by means of the standard methods of descriptive statistics and of the appropriate methods of the statistical analyses (Spearman correlation coefficient of sequential correlation, Kendall coefficient, χ2 - independence test, Kruskal-Wallis test, and others.

  7. Effects of Kapton Sample Cell Windows on the Detection Limit of Smectite: Implications for CheMin on the Mars Science Laboratory Mission

    Science.gov (United States)

    Achilles, C. N.; Ming, Douglas W.; Morris, R. V.; Blake, D. F.

    2012-01-01

    The CheMin instrument on the Mars Science Laboratory (MSL) rover Curiosity is an X-ray diffraction (XRD) and X-ray fluorescence (XRF) instrument capable of providing the mineralogical and chemical compositions of rocks and soils on the surface of Mars. CheMin uses a microfocus X-ray tube with a Co target, transmission geometry, and an energy-discriminating X-ray sensitive CCD to produce simultaneous 2-D XRD patterns and energy-dispersive X-ray histograms from powdered samples. CheMin has two different window materials used for sample cells -- Mylar and Kapton. Instrument details are provided elsewhere. Fe/Mg-smectite (e.g., nontronite) has been identified in Gale Crater, the MSL future landing site, by CRISM spectra. While large quantities of phyllosilicate minerals will be easily detected by CheMin, it is important to establish detection limits of such phases to understand capabilities and limitations of the instrument. A previous study indicated that the (001) peak of smectite at 15 Ang was detectable in a mixture of 1 wt.% smectite with olivine when Mylar is the window material for the sample cell. Complications arise when Kapton is the window material because Kapton itself also has a diffraction peak near 15 Ang (6.8 deg 2 Theta). This study presents results of mineral mixtures of smectite and olivine to determine smectite detection limits for Kapton sample cells. Because the intensity and position of the smectite (001) peak depends on the hydration state, we also analyzed mixtures with "hydrated" and "dehydrated"h smectite to examine the effects of hydration state on detection limits.

  8. How unprecedented a solar minimum was it?

    Science.gov (United States)

    Russell, C T; Jian, L K; Luhmann, J G

    2013-05-01

    The end of the last solar cycle was at least 3 years late, and to date, the new solar cycle has seen mainly weaker activity since the onset of the rising phase toward the new solar maximum. The newspapers now even report when auroras are seen in Norway. This paper is an update of our review paper written during the deepest part of the last solar minimum [1]. We update the records of solar activity and its consequent effects on the interplanetary fields and solar wind density. The arrival of solar minimum allows us to use two techniques that predict sunspot maximum from readings obtained at solar minimum. It is clear that the Sun is still behaving strangely compared to the last few solar minima even though we are well beyond the minimum phase of the cycle 23-24 transition.

  9. Dynamical limits on dark mass in the outer solar system

    International Nuclear Information System (INIS)

    Hogg, D.W.; Quinlan, G.D.; Tremaine, S.

    1991-01-01

    Simplified model solar systems with known observational errors are considered in conducting a dynamical search for dark mass and its minimum detectable amount, and in determining the significance of observed anomalies. The numerical analysis of the dynamical influence of dark mass on the orbits of outer planets and comets is presented in detail. Most conclusions presented are based on observations of the four giant planets where the observational errors in latitude and longitude are independent Gaussian variables with a standard deviation. Neptune's long orbital period cannot be predicted by modern ephemerides, and no evidence of dark mass is found in considering this planet. Studying the improvement in fit when observations are fitted to models that consider dark mass is found to be an efficient way to detect dark mass. Planet X must have a mass of more than about 10 times the minimum detectable mass to locate the hypothetical planet. It is suggested that the IRAS survey would have already located the Planet X if it is so massive and close that it dynamically influences the outer planets. Orbital residuals from comets are found to be more effective than those from planets in detecting the Kuiper belt. 35 refs

  10. Minimum-Cost Reachability for Priced Timed Automata

    DEFF Research Database (Denmark)

    Behrmann, Gerd; Fehnker, Ansgar; Hune, Thomas Seidelin

    2001-01-01

    This paper introduces the model of linearly priced timed automata as an extension of timed automata, with prices on both transitions and locations. For this model we consider the minimum-cost reachability problem: i.e. given a linearly priced timed automaton and a target state, determine...... the minimum cost of executions from the initial state to the target state. This problem generalizes the minimum-time reachability problem for ordinary timed automata. We prove decidability of this problem by offering an algorithmic solution, which is based on a combination of branch-and-bound techniques...

  11. Minimum Q Electrically Small Antennas

    DEFF Research Database (Denmark)

    Kim, O. S.

    2012-01-01

    Theoretically, the minimum radiation quality factor Q of an isolated resonance can be achieved in a spherical electrically small antenna by combining TM1m and TE1m spherical modes, provided that the stored energy in the antenna spherical volume is totally suppressed. Using closed-form expressions...... for a multiarm spherical helix antenna confirm the theoretical predictions. For example, a 4-arm spherical helix antenna with a magnetic-coated perfectly electrically conducting core (ka=0.254) exhibits the Q of 0.66 times the Chu lower bound, or 1.25 times the minimum Q....

  12. 5 CFR 551.702 - Time limits.

    Science.gov (United States)

    2010-01-01

    ... at any time file a complaint under the child labor provisions of the Act or an FLSA claim challenging... claim concerning his or her entitlement to minimum wage or overtime pay for work performed under the Act... limitations is 3 years. In deciding a claim, a determination must be made as to whether the cause or basis of...

  13. Use of sulfur hexafluoride and perfluorocarbon tracers in plutonium storage containers for leak detection

    International Nuclear Information System (INIS)

    Kung, J.K.

    1998-05-01

    This study involves an investigation of the feasibility of a tracer-based leak detection system for long-term interim plutonium storage. In particular, a protocol has been developed based on the use of inert tracers with varying concentrations in order to open-quotes fingerprintclose quotes or open-quotes tagclose quotes specific containers. A particular combination of tracers at specific ratios could be injected into the free volume of each container, allowing for the detection of leaks as well as determination of the location of leaking containers. Based on plutonium storage considerations, sulfur hexafluoride and four perfluorocarbon tracers were selected and should allow a wide range of viable fingerprinting combinations. A open-quotes high-lowclose quotes protocol which uses two distinct chromatographic peak areas or concentration levels, is recommended. Combinations of air exchange rates, detection durations, and detectability limits are examined in order to predict minimum tracer concentrations required for injection in storage containers

  14. Improved detection limit for {sup 59}Ni using the technique of accelerator mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Persson, Per; Erlandsson, Bengt; Hellborg, Ragnar; Kiisk, Madis; Larsson, Ragnar; Skog, Goeran; Stenstroem, Kristina [Lund Univ. (Sweden). Dept. of Nuclear Physics

    2002-11-01

    59 Ni is produced by neutron activation in the stainless steel close to the core of a nuclear reactor. To be able to classify the different parts of the reactor with respect to their content of long-lived radionuclides before final storage it is important to measure the 59 Ni level. Accelerator mass spectrometry is an ultra-sensitive method for counting atoms, suitable for 59 Ni measurements. Improvements in the reduction of the background and in the chemical reduction of cobalt, the interfering isobar, have been made. This chemical purification is essential when using small tandem accelerators, <3 MV, combined with the detection of characteristic projectile X-rays. These improvements have lowered the detection limit for 59 Ni by a factor of twenty compared with the first value reported for the Lund AMS facility. Material from the Swedish nuclear industry has been analysed and examples of the results are presented.

  15. Stochastic variational approach to minimum uncertainty states

    Energy Technology Data Exchange (ETDEWEB)

    Illuminati, F.; Viola, L. [Dipartimento di Fisica, Padova Univ. (Italy)

    1995-05-21

    We introduce a new variational characterization of Gaussian diffusion processes as minimum uncertainty states. We then define a variational method constrained by kinematics of diffusions and Schroedinger dynamics to seek states of local minimum uncertainty for general non-harmonic potentials. (author)

  16. Detection thresholds of macaque otolith afferents.

    Science.gov (United States)

    Yu, Xiong-Jie; Dickman, J David; Angelaki, Dora E

    2012-06-13

    The vestibular system is our sixth sense and is important for spatial perception functions, yet the sensory detection and discrimination properties of vestibular neurons remain relatively unexplored. Here we have used signal detection theory to measure detection thresholds of otolith afferents using 1 Hz linear accelerations delivered along three cardinal axes. Direction detection thresholds were measured by comparing mean firing rates centered on response peak and trough (full-cycle thresholds) or by comparing peak/trough firing rates with spontaneous activity (half-cycle thresholds). Thresholds were similar for utricular and saccular afferents, as well as for lateral, fore/aft, and vertical motion directions. When computed along the preferred direction, full-cycle direction detection thresholds were 7.54 and 3.01 cm/s(2) for regular and irregular firing otolith afferents, respectively. Half-cycle thresholds were approximately double, with excitatory thresholds being half as large as inhibitory thresholds. The variability in threshold among afferents was directly related to neuronal gain and did not depend on spike count variance. The exact threshold values depended on both the time window used for spike count analysis and the filtering method used to calculate mean firing rate, although differences between regular and irregular afferent thresholds were independent of analysis parameters. The fact that minimum thresholds measured in macaque otolith afferents are of the same order of magnitude as human behavioral thresholds suggests that the vestibular periphery might determine the limit on our ability to detect or discriminate small differences in head movement, with little noise added during downstream processing.

  17. Use of FTA sampling cards for molecular detection of avian influenza virus in wild birds.

    Science.gov (United States)

    Keeler, Shamus P; Ferro, Pamela J; Brown, Justin D; Fang, Xingwang; El-Attrache, John; Poulson, Rebecca; Jackwood, Mark W; Stallknecht, David E

    2012-03-01

    Current avian influenza (AI) virus surveillance programs involving wild birds rely on sample collection methods that require refrigeration or low temperature freezing to maintain sample integrity for virus isolation and/or reverse-transcriptase (RT) PCR. Maintaining the cold chain is critical for the success of these diagnostic assays but is not always possible under field conditions. The aim of this study was to test the utility of Finders Technology Associates (FTA) cards for reliable detection of AI virus from cloacal and oropharyngeal swabs of wild birds. The minimum detectable titer was determined, and the effect of room temperature storage was evaluated experimentally using multiple egg-propagated stock viruses (n = 6). Using real time RT-PCR, we compared results from paired cloacal swab and samples collected on FTA cards from both experimentally infected mallards (Anasplatyrhynchos) and hunter-harvested waterfowl sampled along the Texas Gulf Coast. Based on the laboratory trials, the average minimal detectable viral titer was determined to be 1 x 10(4.7) median embryo infectious dose (EID50)/ml (range: 1 x 10(4.3) to 1 x 10(5.4) EID50/ml), and viral RNA was consistently detectable on the FTA cards for a minimum of 20 days and up to 30 days for most subtypes at room temperature (23 C) storage. Real-time RT-PCR of samples collected using the FTA cards showed fair to good agreement in live birds when compared with both real-time RT-PCR and virus isolation of swabs. AI virus detection rates in samples from several wild bird species were higher when samples were collected using the FTA cards compared with cloacal swabs. These results suggest that FTA cards can be used as an alternative sample collection method when traditional surveillance methods are not possible, especially in avian populations that have historically received limited testing or situations in which field conditions limit the ability to properly store or ship swab samples.

  18. Minimum entropy production principle

    Czech Academy of Sciences Publication Activity Database

    Maes, C.; Netočný, Karel

    2013-01-01

    Roč. 8, č. 7 (2013), s. 9664-9677 ISSN 1941-6016 Institutional support: RVO:68378271 Keywords : MINEP Subject RIV: BE - Theoretical Physics http://www.scholarpedia.org/article/Minimum_entropy_production_principle

  19. Parker limit for monopoles with large magnetic charge

    International Nuclear Information System (INIS)

    Hodges, H.M.; Kolb, E.W.; Turner, M.S.

    1986-01-01

    The survival of galactic magnetic fields places a limit on the flux of magnetic monopoles, the so-called ''Parker limit.'' Previous discussions of the Parker limit have assumed that the charge of the monopole is the Dirac value, g/sub Dirac/ = 2π/e. However, if the grand unified group is broken by Wilson lines, as is assumed in some superstring models, the minimum value of the magnetic charge is not the Dirac quantum, but an integer multiple of it. In this brief report we investigate the dependence of the Parker limit on the charge of the magnetic monopole. 10 refs., 1 fig

  20. Microbial eukaryote diversity in the marine oxygen minimum zone off northern Chile

    OpenAIRE

    Parris, Darren J.; Ganesh, Sangita; Edgcomb, Virginia P.; Stewart, Frank J.; DeLong, Edward

    2014-01-01

    Molecular surveys are revealing diverse eukaryotic assemblages in oxygen-limited ocean waters. These communities may play pivotal ecological roles through autotrophy, feeding, and a wide range of symbiotic associations with prokaryotes. We used 18S rRNA gene sequencing to provide the first snapshot of pelagic microeukaryotic community structure in two cellular size fractions (0.2-1.6 µm, >1.6 µm) from seven depths through the anoxic oxygen minimum zone (OMZ) off northern Chile. Sequencing ...

  1. X-ray nanoprobes and diffraction-limited storage rings: opportunities and challenges of fluorescence tomography of biological specimens

    Energy Technology Data Exchange (ETDEWEB)

    Jonge, Martin D. de, E-mail: martin.dejonge@synchrotron.org.au [Australian Synchrotron, 800 Blackburn Road, Clayton, Victoria 3168 (Australia); Ryan, Christopher G. [CSIRO Earth Science and Research Engineering, Clayton, Victoria 3168 (Australia); Jacobsen, Chris J. [Advanced Photon Source, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL 60439 (United States); Department of Physics, Chemistry of Life Processes Institute, Northwestern University, 2170 Campus Drive, Evanston, IL 60208 (United States); Chemistry of Life Processes Institute, Northwestern University, 2170 Campus Drive, Evanston, IL 60208 (United States)

    2014-08-27

    Nanoscale X-ray scanning microscopes, or X-ray nanoprobes, will benefit greatly from diffraction-limited storage rings. Here the requirements for nanoscale fluorescence tomography are explored to gain insight into the scientific opportunities and technical challenges that such sources offer. X-ray nanoprobes require coherent illumination to achieve optic-limited resolution, and so will benefit directly from diffraction-limited storage rings. Here, the example of high-resolution X-ray fluorescence tomography is focused on as one of the most voracious demanders of coherent photons, since the detected signal is only a small fraction of the incident flux. Alternative schemes are considered for beam delivery, sample scanning and detectors. One must consider as well the steps before and after the X-ray experiment: sample preparation and examination conditions, and analysis complexity due to minimum dose requirements and self-absorption. By understanding the requirements and opportunities for nanoscale fluorescence tomography, one gains insight into the R&D challenges in optics and instrumentation needed to fully exploit the source advances that diffraction-limited storage rings offer.

  2. Microbial oceanography of anoxic oxygen minimum zones

    DEFF Research Database (Denmark)

    Ulloa, Osvaldo; Canfield, Donald E; DeLong, Edward F

    2012-01-01

    oxide (N(2)O) gases. Anaerobic microbial processes, including the two pathways of N(2) production, denitrification and anaerobic ammonium oxidation, are oxygen-sensitive, with some occurring only under strictly anoxic conditions. The detection limit of the usual method (Winkler titrations) for measuring...

  3. Minimum emittance in TBA and MBA lattices

    Science.gov (United States)

    Xu, Gang; Peng, Yue-Mei

    2015-03-01

    For reaching a small emittance in a modern light source, triple bend achromats (TBA), theoretical minimum emittance (TME) and even multiple bend achromats (MBA) have been considered. This paper derived the necessary condition for achieving minimum emittance in TBA and MBA theoretically, where the bending angle of inner dipoles has a factor of 31/3 bigger than that of the outer dipoles. Here, we also calculated the conditions attaining the minimum emittance of TBA related to phase advance in some special cases with a pure mathematics method. These results may give some directions on lattice design.

  4. Minimum emittance in TBA and MBA lattices

    International Nuclear Information System (INIS)

    Xu Gang; Peng Yuemei

    2015-01-01

    For reaching a small emittance in a modern light source, triple bend achromats (TBA), theoretical minimum emittance (TME) and even multiple bend achromats (MBA) have been considered. This paper derived the necessary condition for achieving minimum emittance in TBA and MBA theoretically, where the bending angle of inner dipoles has a factor of 3 1/3 bigger than that of the outer dipoles. Here, we also calculated the conditions attaining the minimum emittance of TBA related to phase advance in some special cases with a pure mathematics method. These results may give some directions on lattice design. (authors)

  5. Globally optimal, minimum stored energy, double-doughnut superconducting magnets.

    Science.gov (United States)

    Tieng, Quang M; Vegh, Viktor; Brereton, Ian M

    2010-01-01

    The use of the minimum stored energy current density map-based methodology of designing closed-bore symmetric superconducting magnets was described recently. The technique is further developed to cater for the design of interventional-type MRI systems, and in particular open symmetric magnets of the double-doughnut configuration. This extends the work to multiple magnet domain configurations. The use of double-doughnut magnets in MRI scanners has previously been hindered by the ability to deliver strong magnetic fields over a sufficiently large volume appropriate for imaging, essentially limiting spatial resolution, signal-to-noise ratio, and field of view. The requirement of dedicated interventional space restricts the manner in which the coils can be arranged and placed. The minimum stored energy optimal coil arrangement ensures that the field strength is maximized over a specific region of imaging. The design method yields open, dual-domain magnets capable of delivering greater field strengths than those used prior to this work, and at the same time it provides an increase in the field-of-view volume. Simulation results are provided for 1-T double-doughnut magnets with at least a 50-cm 1-ppm (parts per million) field of view and 0.7-m gap between the two doughnuts. Copyright (c) 2009 Wiley-Liss, Inc.

  6. Thermal background noise limitations

    Science.gov (United States)

    Gulkis, S.

    1982-01-01

    Modern detection systems are increasingly limited in sensitivity by the background thermal photons which enter the receiving system. Expressions for the fluctuations of detected thermal radiation are derived. Incoherent and heterodyne detection processes are considered. References to the subject of photon detection statistics are given.

  7. A reversed-phase compatible thin-layer chromatography autography for the detection of acetylcholinesterase inhibitors.

    Science.gov (United States)

    Ramallo, I Ayelen; García, Paula; Furlan, Ricardo L E

    2015-11-01

    A dual readout autographic assay to detect acetylcholinesterase inhibitors present in complex matrices adsorbed on reversed-phase or normal-phase thin-layer chromatography plates is described. Enzyme gel entrapment with an amphiphilic copolymer was used for assay development. The effects of substrate and enzyme concentrations, pH, incubation time, and incubation temperature on the sensitivity and the detection limit of the assay were evaluated. Experimental design and response surface methodology were used to optimize conditions with a minimum number of experiments. The assay allowed the detection of 0.01% w/w of physostigmine in both a spiked Sonchus oleraceus L. extract chromatographed on normal phase and a spiked Pimenta racemosa (Mill.) J.W. Moore leaf essential oil chromatographed on reversed phase. Finally, the reversed-phase thin-layer chromatography assay was applied to reveal the presence of an inhibitor in the Cymbopogon citratus (DC.) Stapf essential oil. The developed assay is able to detect acetylcholinesterase inhibitors present in complex matrixes that were chromatographed in normal phase or reversed-phase thin-layer chromatography. The detection limit for physostigmine on both normal and reversed phase was of 1×10(-4) μg. The results can be read by a change in color and/or a change in fluorescence. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Detailed spectroscopy in the superdeformed second minimum of 240Pu

    International Nuclear Information System (INIS)

    Thirolf, P.G.; Gassmann, D.; Habs, D.; Chromik, M.J.; Eisermann, Y.; Graw, G.; Hertenberger, R.; Maier, H.J.; Metz, A.; Reiter, P.

    2000-01-01

    Complete text of publication follows. Superdeformed prolate nuclei, having an axis ratio of about 2:1, have first been discovered in fission isomers in the actinide region almost 40 years ago by Polikanov et al.. Their interpretation of being the result of microscopic shell corrections on top of the macroscopic liquid drop potential leading to a second minimum in the nuclear potential energy surface is well established. 240 Pu with its 3.7 ns fission isomer may be regarded as the prototype nucleus for spectroscopic studies of superdeformed actinide nuclei since the identification of the ground state rotational band in conversion electron measurements [1]. Though from the knowledge on excited states in the first minimum and previous measurements in the second minimum low-lying collective excitations in the second minimum low-lying collective excitations in the second well of 240 Pu can be expected, none of them has been experimentally identified so far. Quite surprisingly, no low-lying collective quadrupole excitations could be observed in a recent detailed high-resolution and high-efficiency γ-spectroscopy experiment [2]. Complementary information could be obtained in conversion electron measurements in coincidence with isomeric fission performed at the Garching Accelerator Laboratory, resulting in the first identification of the lowest β-vibrational band [3]. In a combined analysis of the γ-spectroscopic and conversion electron data conversion coefficients α K or limits on α K could be deduced, thus allowing to determine the multipolarities of the transitions. A predominant population of negative parity states in the second well could be observed that can be explained by the filtering function of the inner and outer fission barrier. Complementary transmission resonance measurements have been performed, yielding new information on the fine structure of (β-)vibrational multi-phonon states. A new method could be established to determine the excitation energy of

  9. Conversion and matched filter approximations for serial minimum-shift keyed modulation

    Science.gov (United States)

    Ziemer, R. E.; Ryan, C. R.; Stilwell, J. H.

    1982-01-01

    Serial minimum-shift keyed (MSK) modulation, a technique for generating and detecting MSK using series filtering, is ideally suited for high data rate applications provided the required conversion and matched filters can be closely approximated. Low-pass implementations of these filters as parallel inphase- and quadrature-mixer structures are characterized in this paper in terms of signal-to-noise ratio (SNR) degradation from ideal and envelope deviation. Several hardware implementation techniques utilizing microwave devices or lumped elements are presented. Optimization of parameter values results in realizations whose SNR degradation is less than 0.5 dB at error probabilities of .000001.

  10. 41 CFR 50-202.2 - Minimum wage in all industries.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Minimum wage in all... Public Contracts PUBLIC CONTRACTS, DEPARTMENT OF LABOR 202-MINIMUM WAGE DETERMINATIONS Groups of Industries § 50-202.2 Minimum wage in all industries. In all industries, the minimum wage applicable to...

  11. Detection limits in the chromatographic element trace analysis - quantitative TLC, HPLC and GC with the example of beryllium acetylacetonate

    International Nuclear Information System (INIS)

    Schwedt, G.

    1981-01-01

    Chromatographic analyses of beryllium acetylacetonate are carried out in synthetic solutions within the nano- and picogram range of beryllium. For thin-layer chromatography (TLC) normal and silanized silica gel is used, for high-performance liquid chromatography (HPLC) silica gel of 7 μm particles, for gas chromatography (GC) silicone SE-30 as stationary phase. Visual evaluation and remission measurements in TLC, UV-254 nm absorption measurements in HPLC and measurements with a FID in GC are employed for the determination of the calibration curves. A calibration curve through the origin and a detection limit of 150 pg Be determinable form are received by HPLC only. For trace analyses by GC a new definition of a detection limit for the evaluation of substance peaks on a solvent tailing is suggested. (orig.) [de

  12. Estimation of the limit of detection in semiconductor gas sensors through linearized calibration models.

    Science.gov (United States)

    Burgués, Javier; Jiménez-Soto, Juan Manuel; Marco, Santiago

    2018-07-12

    The limit of detection (LOD) is a key figure of merit in chemical sensing. However, the estimation of this figure of merit is hindered by the non-linear calibration curve characteristic of semiconductor gas sensor technologies such as, metal oxide (MOX), gasFETs or thermoelectric sensors. Additionally, chemical sensors suffer from cross-sensitivities and temporal stability problems. The application of the International Union of Pure and Applied Chemistry (IUPAC) recommendations for univariate LOD estimation in non-linear semiconductor gas sensors is not straightforward due to the strong statistical requirements of the IUPAC methodology (linearity, homoscedasticity, normality). Here, we propose a methodological approach to LOD estimation through linearized calibration models. As an example, the methodology is applied to the detection of low concentrations of carbon monoxide using MOX gas sensors in a scenario where the main source of error is the presence of uncontrolled levels of humidity. Copyright © 2018 Elsevier B.V. All rights reserved.

  13. 29 CFR 525.13 - Renewal of special minimum wage certificates.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Renewal of special minimum wage certificates. 525.13... minimum wage certificates. (a) Applications may be filed for renewal of special minimum wage certificates.... (c) Workers with disabilities may not continue to be paid special minimum wages after notice that an...

  14. Study of the influence of the time temperature profile on the minimum detectable dose of TLD-100

    Energy Technology Data Exchange (ETDEWEB)

    Meireles, Leonardo S.; Lacerda, Marco Aurelio S.; Meira-Belo, Luiz C.; Ferreira, Hudson R., E-mail: meirelesls@cdtn.br, E-mail: masl@cdtn.br, E-mail: lcmb@cdtn.br, E-mail: hrf@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2013-07-01

    Monitoring of workers and workplaces is an integral part of any radiation protection programme (RPP). It is essential to demonstrate compliance with regulations that limit the allowable dose to the public from manmade sources and to enable the responsible of the installations to verify compliance with the legal dose limits to the workers and ALARA goals. Thermoluminescent dosemeters (TLDs) are generally employed to assess the environmental and personnel doses. To completely characterize a TLD dosimetry system is fundamental to determine the Lowest Dose that the system is capable of measuring. As the amount of the light emitted by TLD material is a function of the time temperature profile (TTP), in the present study, the influence of the TTP on the Detection Threshold (MDD) of the LiF:Mg,Ti (TLD-100) detectors was evaluated. Eighteen different TTPs were tested for two different annealing processes: (I) utilization of the TTP itself and; (II) a microprocessor controlled oven annealing procedure. Results showed that TTP choice can influence significantly in the MDD values. The worst results were generally found for TLDs annealed by the TTP itself. The lack of pattern or the unexpected behavior to the influence of some parameters of the TTP on the calculated MDDs must be carefully investigated. Greater variations on the TTP parameters must be undertaken. Special attention must be also done on the methodology of calculating the MDDs. (author)

  15. Study of the influence of the time temperature profile on the minimum detectable dose of TLD-100

    International Nuclear Information System (INIS)

    Meireles, Leonardo S.; Lacerda, Marco Aurelio S.; Meira-Belo, Luiz C.; Ferreira, Hudson R.

    2013-01-01

    Monitoring of workers and workplaces is an integral part of any radiation protection programme (RPP). It is essential to demonstrate compliance with regulations that limit the allowable dose to the public from manmade sources and to enable the responsible of the installations to verify compliance with the legal dose limits to the workers and ALARA goals. Thermoluminescent dosemeters (TLDs) are generally employed to assess the environmental and personnel doses. To completely characterize a TLD dosimetry system is fundamental to determine the Lowest Dose that the system is capable of measuring. As the amount of the light emitted by TLD material is a function of the time temperature profile (TTP), in the present study, the influence of the TTP on the Detection Threshold (MDD) of the LiF:Mg,Ti (TLD-100) detectors was evaluated. Eighteen different TTPs were tested for two different annealing processes: (I) utilization of the TTP itself and; (II) a microprocessor controlled oven annealing procedure. Results showed that TTP choice can influence significantly in the MDD values. The worst results were generally found for TLDs annealed by the TTP itself. The lack of pattern or the unexpected behavior to the influence of some parameters of the TTP on the calculated MDDs must be carefully investigated. Greater variations on the TTP parameters must be undertaken. Special attention must be also done on the methodology of calculating the MDDs. (author)

  16. An Empirical Analysis of the Relationship between Minimum Wage ...

    African Journals Online (AJOL)

    An Empirical Analysis of the Relationship between Minimum Wage, Investment and Economic Growth in Ghana. ... In addition, the ratio of public investment to tax revenue must increase as minimum wage increases since such complementary changes are more likely to lead to economic growth. Keywords: minimum wage ...

  17. 12 CFR 3.6 - Minimum capital ratios.

    Science.gov (United States)

    2010-01-01

    ... should have well-diversified risks, including no undue interest rate risk exposure; excellent control... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Minimum capital ratios. 3.6 Section 3.6 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY MINIMUM CAPITAL RATIOS; ISSUANCE...

  18. 12 CFR 615.5330 - Minimum surplus ratios.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Minimum surplus ratios. 615.5330 Section 615.5330 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM FUNDING AND FISCAL AFFAIRS, LOAN POLICIES AND OPERATIONS, AND FUNDING OPERATIONS Surplus and Collateral Requirements § 615.5330 Minimum...

  19. Unmanned Aircraft Systems Detect and Avoid System: End-to-End Verification and Validation Simulation Study of Minimum Operations Performance Standards for Integrating Unmanned Aircraft into the National Airspace System

    Science.gov (United States)

    Ghatas, Rania W.; Jack, Devin P.; Tsakpinis, Dimitrios; Sturdy, James L.; Vincent, Michael J.; Hoffler, Keith D.; Myer, Robert R.; DeHaven, Anna M.

    2017-01-01

    As Unmanned Aircraft Systems (UAS) make their way to mainstream aviation operations within the National Airspace System (NAS), research efforts are underway to develop a safe and effective environment for their integration into the NAS. Detect and Avoid (DAA) systems are required to account for the lack of "eyes in the sky" due to having no human on-board the aircraft. The technique, results, and lessons learned from a detailed End-to-End Verification and Validation (E2-V2) simulation study of a DAA system representative of RTCA SC-228's proposed Phase I DAA Minimum Operational Performance Standards (MOPS), based on specific test vectors and encounter cases, will be presented in this paper.

  20. 5 CFR 551.601 - Minimum age standards.

    Science.gov (United States)

    2010-01-01

    ... ADMINISTRATION UNDER THE FAIR LABOR STANDARDS ACT Child Labor § 551.601 Minimum age standards. (a) 16-year... subject to its child labor provisions, with certain exceptions not applicable here. (b) 18-year minimum... occupation found and declared by the Secretary of Labor to be particularly hazardous for the employment of...

  1. 12 CFR 932.8 - Minimum liquidity requirements.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Minimum liquidity requirements. 932.8 Section... CAPITAL STANDARDS FEDERAL HOME LOAN BANK CAPITAL REQUIREMENTS § 932.8 Minimum liquidity requirements. In addition to meeting the deposit liquidity requirements contained in § 965.3 of this chapter, each Bank...

  2. Non-targeted detection of chemical contamination in carbonated soft drinks using NMR spectroscopy, variable selection and chemometrics

    Energy Technology Data Exchange (ETDEWEB)

    Charlton, Adrian J. [Department for Environment, Food and Rural Affairs, Central Science Laboratory, Sand Hutton, York YO41 1LZ (United Kingdom)], E-mail: adrian.charlton@csl.gov.uk; Robb, Paul; Donarski, James A.; Godward, John [Department for Environment, Food and Rural Affairs, Central Science Laboratory, Sand Hutton, York YO41 1LZ (United Kingdom)

    2008-06-23

    An efficient method for detecting malicious and accidental contamination of foods has been developed using a combined {sup 1}H nuclear magnetic resonance (NMR) and chemometrics approach. The method has been demonstrated using a commercially available carbonated soft drink, as being capable of identifying atypical products and to identify contaminant resonances. Soft-independent modelling of class analogy (SIMCA) was used to compare {sup 1}H NMR profiles of genuine products (obtained from the manufacturer) against retail products spiked in the laboratory with impurities. The benefits of using feature selection for extracting contaminant NMR frequencies were also assessed. Using example impurities (paraquat, p-cresol and glyphosate) NMR spectra were analysed using multivariate methods resulting in detection limits of approximately 0.075, 0.2, and 0.06 mM for p-cresol, paraquat and glyphosate, respectively. These detection limits are shown to be approximately 100-fold lower than the minimum lethal dose for paraquat. The methodology presented here is used to assess the composition of complex matrices for the presence of contaminating molecules without a priori knowledge of the nature of potential contaminants. The ability to detect if a sample does not fit into the expected profile without recourse to multiple targeted analyses is a valuable tool for incident detection and forensic applications.

  3. Non-targeted detection of chemical contamination in carbonated soft drinks using NMR spectroscopy, variable selection and chemometrics

    International Nuclear Information System (INIS)

    Charlton, Adrian J.; Robb, Paul; Donarski, James A.; Godward, John

    2008-01-01

    An efficient method for detecting malicious and accidental contamination of foods has been developed using a combined 1 H nuclear magnetic resonance (NMR) and chemometrics approach. The method has been demonstrated using a commercially available carbonated soft drink, as being capable of identifying atypical products and to identify contaminant resonances. Soft-independent modelling of class analogy (SIMCA) was used to compare 1 H NMR profiles of genuine products (obtained from the manufacturer) against retail products spiked in the laboratory with impurities. The benefits of using feature selection for extracting contaminant NMR frequencies were also assessed. Using example impurities (paraquat, p-cresol and glyphosate) NMR spectra were analysed using multivariate methods resulting in detection limits of approximately 0.075, 0.2, and 0.06 mM for p-cresol, paraquat and glyphosate, respectively. These detection limits are shown to be approximately 100-fold lower than the minimum lethal dose for paraquat. The methodology presented here is used to assess the composition of complex matrices for the presence of contaminating molecules without a priori knowledge of the nature of potential contaminants. The ability to detect if a sample does not fit into the expected profile without recourse to multiple targeted analyses is a valuable tool for incident detection and forensic applications

  4. Responsiveness and minimum important change of the Oswestry Disability Index in Italian subjects with symptomatic lumbar spondylolisthesis.

    Science.gov (United States)

    Vanti, Carla; Ferrari, Silvano; Villafañe, Jorge Hugo; Berjano, Pedro; Monticone, Marco

    2017-06-01

    This study aims to investigate the responsiveness and the minimum important change of the Italian version of the Oswestry Disability Index (ODI-I) in subjects with symptomatic specific low back pain associated with lumbar spondylolisthesis (SPL). One hundred and fifty-one patients with symptomatic SPL completed the ODI-I, a 0-100 numerical rating scale (NRS), and performed the prone and supine bridge tests. The global perception of effectiveness was measured with a 7-point Likert scale. Responsiveness was assessed by distribution methods (minimum detectable change [MDC], effect size [ES], standardized response mean [SRM]) and anchor-based methods (ROC curves). The MDC was 4.23, the ES was 0.95 and the SRM was 1.25. ROC analysis revealed an area under the curve of 0.76 indicating moderate discriminating capacity. The best cut-off point for the dichotomous outcome was 7.5 (sensitivity 90.3%, specificity 56.7%). . The ODI-I proved to be responsive in detecting changes after conservative treatment in subjects with lumbar SPL. II.

  5. A prototype detection system for atmospheric monitoring of xenon radioisotopes

    Science.gov (United States)

    Czyz, Steven A.; Farsoni, Abi T.; Ranjbar, Lily

    2018-03-01

    The design of a radioxenon detection system utilizing a CdZeTe crystal and a plastic scintillator coupled to an array of SiPMs to conduct beta-gamma coincidence detection for atmospheric radioxenon monitoring, as well as the measurement of 135Xe and 133/133mXe, have been detailed previously. This paper presents recent measurements of 133/133mXe and 131mXe and the observation of conversion electrons in their coincidence spectra, as well as a 48-hour background measurement to calculate the Minimum Detectable Concentration (MDC) of radioxenon isotopes in the system. The identification of Regions of Interest (ROIs) in the coincidence spectra yielded from the radioxenon measurements, and the subsequent calculation of the MDCs of the system for 135Xe, 133/133mXe, and 131mXe, are also discussed. Calculated MDCs show that the detection system preforms respectably when compared to other state of the art radioxenon detection systems and achieved an MDC of less than 1 mBq/m3 for 131mXe, 133Xe, and 133mXe, in accordance with limits set by the Comprehensive Nuclear-Test-Ban Treaty (CTBTO). The system also provides the advantage of room temperature operation, compactness, low noise operation and having simple readout electronics.

  6. [Hospitals failing minimum volumes in 2004: reasons and consequences].

    Science.gov (United States)

    Geraedts, M; Kühnen, C; Cruppé, W de; Blum, K; Ohmann, C

    2008-02-01

    In 2004 Germany introduced annual minimum volumes nationwide on five surgical procedures: kidney, liver, stem cell transplantation, complex oesophageal, and pancreatic interventions. Hospitals that fail to reach the minimum volumes are no longer allowed to perform the respective procedures unless they raise one of eight legally accepted exceptions. The goal of our study was to investigate how many hospitals fell short of the minimum volumes in 2004, whether and how this was justified, and whether hospitals that failed the requirements experienced any consequences. We analysed data on meeting the minimum volume requirements in 2004 that all German hospitals were obliged to publish as part of their biannual structured quality reports. We performed telephone interviews: a) with all hospitals not achieving the minimum volumes for complex oesophageal, and pancreatic interventions, and b) with the national umbrella organisations of all German sickness funds. In 2004, one quarter of all German acute care hospitals (N=485) performed 23,128 procedures where minimum volumes applied. 197 hospitals (41%) did not meet at least one of the minimum volumes. These hospitals performed N=715 procedures (3.1%) where the minimum volumes were not met. In 43% of these cases the hospitals raised legally accepted exceptions. In 33% of the cases the hospitals argued using reasons that were not legally acknowledged. 69% of those hospitals that failed to achieve the minimum volumes for complex oesophageal and pancreatic interventions did not experience any consequences from the sickness funds. However, one third of those hospitals reported that the sickness funds addressed the issue and partially announced consequences for the future. The sickness funds' umbrella organisations stated that there were only sparse activities related to the minimum volumes and that neither uniform registrations nor uniform proceedings in case of infringements of the standards had been agreed upon. In spite of the

  7. The Distribution of the Sample Minimum-Variance Frontier

    OpenAIRE

    Raymond Kan; Daniel R. Smith

    2008-01-01

    In this paper, we present a finite sample analysis of the sample minimum-variance frontier under the assumption that the returns are independent and multivariate normally distributed. We show that the sample minimum-variance frontier is a highly biased estimator of the population frontier, and we propose an improved estimator of the population frontier. In addition, we provide the exact distribution of the out-of-sample mean and variance of sample minimum-variance portfolios. This allows us t...

  8. radiation safety culture for developing country: Basis for s minimum operational radiation protection programme

    International Nuclear Information System (INIS)

    Rozental, J. J.

    1997-01-01

    The purpose of this document is to present a methodology for an integrated strategy aiming at establishing an adequate radiation Safety infrastructure for developing countries, non major power reactor programme. Its implementation will allow these countries, about 50% of the IAEA's Member States, to improve marginal radiation safety, specially to those recipients of technical assistance and do not meet the Minimum radiation Safety Requirements of the IAEA's Basic Safety Standards for radiation protection Progress in the implementation of safety regulations depends on the priority of the government and its understanding and conviction about the basic requirements for protection against the risks associated with exposure to ionizing radiation. There is no doubt to conclude that the reasons for the deficiency of sources control and dose limitation are related to the lack of an appropriate legal and regulatory framework, specially considering the establishment of an adequate legislation; A minimum legal infrastructure; A minimum operational radiation safety programme; Alternatives for a Point of Optimum Contact, to avoid overlap and conflict, that is: A 'Memorandum of Understanding' among Regulatory Authorities in the Country, dealing with similar type of licensing and inspection

  9. Characteristics of low-latitude ionospheric depletions and enhancements during solar minimum

    Science.gov (United States)

    Haaser, R. A.; Earle, G. D.; Heelis, R. A.; Klenzing, J.; Stoneback, R.; Coley, W. R.; Burrell, A. G.

    2012-10-01

    Under the waning solar minimum conditions during 2009 and 2010, the Ion Velocity Meter, part of the Coupled Ion Neutral Dynamics Investigation aboard the Communication/Navigation Outage Forecasting System satellite, is used to measure in situ nighttime ion densities and drifts at altitudes between 400 and 550 km during the hours 21:00-03:00 solar local time. A new approach to detecting and classifying well-formed ionospheric plasma depletions and enhancements (bubbles and blobs) with scale sizes between 50 and 500 km is used to develop geophysical statistics for the summer, winter, and equinox seasons during the quiet solar conditions. Some diurnal and seasonal geomagnetic distribution characteristics confirm previous work on equatorial irregularities and scintillations, while other elements reveal new behaviors that will require further investigation before they may be fully understood. Events identified in the study reveal very different and often opposite behaviors of bubbles and blobs during solar minimum. In particular, more bubbles demonstrating deeper density fluctuations and faster perturbation plasma drifts typically occur earlier near the magnetic equator, while blobs of similar magnitude occur more often far away from the geomagnetic equator closer to midnight.

  10. 24 CFR 891.145 - Owner deposit (Minimum Capital Investment).

    Science.gov (United States)

    2010-04-01

    ... General Program Requirements § 891.145 Owner deposit (Minimum Capital Investment). As a Minimum Capital... Investment shall be one-half of one percent (0.5%) of the HUD-approved capital advance, not to exceed $25,000. ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Owner deposit (Minimum Capital...

  11. SU-F-J-206: Systematic Evaluation of the Minimum Detectable Shift Using a Range- Finding Camera

    Energy Technology Data Exchange (ETDEWEB)

    Platt, M; Platt, M [College of Medicine University of Cincinnati, Cincinnati, OH (United States); Lamba, M [University of Cincinnati, Cincinnati, OH (United States); Mascia, A [University of Cincinnati Medical Center, Cincinnati, OH (United States); Huang, K [UC Health Barret Cancer Center, Cincinnati, OH (United States)

    2016-06-15

    Purpose: The robotic table used for patient alignment in proton therapy is calibrated only at commissioning under well-defined conditions and table shifts may vary over time and with differing conditions. The purpose of this study is to systematically investigate minimum detectable shifts using a time-of-flight (TOF) range-finding camera for table position feedback. Methods: A TOF camera was used to acquire one hundred 424 × 512 range images from a flat surface before and after known shifts. Range was assigned by averaging central regions of the image across multiple images. Depth resolution was determined by evaluating the difference between the actual shift of the surface and the measured shift. Depth resolution was evaluated for number of images averaged, area of sensor over which depth was averaged, distance from camera to surface, central versus peripheral image regions, and angle of surface relative to camera. Results: For one to one thousand images with a shift of one millimeter the range in error was 0.852 ± 0.27 mm to 0.004 ± 0.01 mm (95% C.I.). For varying regions of the camera sensor the range in error was 0.02 ± 0.05 mm to 0.47 ± 0.04 mm. The following results are for 10 image averages. For areas ranging from one pixel to 9 × 9 pixels the range in error was 0.15 ± 0.09 to 0.29 ± 0.15 mm (1σ). For distances ranging from two to four meters the range in error was 0.15 ± 0.09 to 0.28 ± 0.15 mm. For an angle of incidence between thirty degrees and ninety degrees the average range in error was 0.11 ± 0.08 to 0.17 ± 0.09 mm. Conclusion: It is feasible to use a TOF camera for measuring shifts in flat surfaces under clinically relevant conditions with submillimeter precision.

  12. Installation of high-resolution ERDA in UTTAC at the University of Tsukuba: Determination of the energy resolution and the detection limit for hydrogen

    Energy Technology Data Exchange (ETDEWEB)

    Sekiba, D., E-mail: sekiba@tac.tsukuba.ac.jp [Institute of Applied Physics, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki 305-8573 (Japan); University of Tsukuba, Tandem Accelerator Complex (UTTAC), Tennodai 1-1-1, Tsukuba, Ibaraki 305-8577 (Japan); Chito, K.; Harayama, I. [Institute of Applied Physics, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki 305-8573 (Japan); Watahiki, Y.; Ishii, S. [University of Tsukuba, Tandem Accelerator Complex (UTTAC), Tennodai 1-1-1, Tsukuba, Ibaraki 305-8577 (Japan); Ozeki, K. [Department of Mechanical Engineering, Ibaraki University, Nakanarusawa 4-12-1, Hitachi, Ibaraki 316-8511 (Japan)

    2017-06-15

    A newly developed high-resolution elastic recoil detection analysis (HERDA) system installed at the 1 MV Tandetron in UTTAC at the University of Tsukuba is introduced. The effective solid angle of detector, energy resolution and detection limit for hydrogen are, for the first time, determined quantitatively by the measurements on an a-C:H (and D) film deposited on a Si substrate. In the case of a 500 keV {sup 16}O{sup +} as the incident beam, an energy resolution of ∼0.45 keV and a detection limit of ∼3.8 × 10{sup 20} atoms/cm{sup 3} (∼0.18 at.%) with a data acquisition time of ∼310 s are derived.

  13. Minimum Wages and the Distribution of Family Incomes

    OpenAIRE

    Dube, Arindrajit

    2017-01-01

    Using the March Current Population Survey data from 1984 to 2013, I provide a comprehensive evaluation of how minimum wage policies influence the distribution of family incomes. I find robust evidence that higher minimum wages shift down the cumulative distribution of family incomes at the bottom, reducing the share of non-elderly individuals with incomes below 50, 75, 100, and 125 percent of the federal poverty threshold. The long run (3 or more years) minimum wage elasticity of the non-elde...

  14. 7 CFR 1610.5 - Minimum Bank loan.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Minimum Bank loan. 1610.5 Section 1610.5 Agriculture Regulations of the Department of Agriculture (Continued) RURAL TELEPHONE BANK, DEPARTMENT OF AGRICULTURE LOAN POLICIES § 1610.5 Minimum Bank loan. A Bank loan will not be made unless the applicant qualifies for a Bank...

  15. Minimum Wage Effects in the Longer Run

    Science.gov (United States)

    Neumark, David; Nizalova, Olena

    2007-01-01

    Exposure to minimum wages at young ages could lead to adverse longer-run effects via decreased labor market experience and tenure, and diminished education and training, while beneficial longer-run effects could arise if minimum wages increase skill acquisition. Evidence suggests that as individuals reach their late 20s, they earn less the longer…

  16. 29 CFR 783.43 - Computation of seaman's minimum wage.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Computation of seaman's minimum wage. 783.43 Section 783.43...'s minimum wage. Section 6(b) requires, under paragraph (2) of the subsection, that an employee...'s minimum wage requirements by reason of the 1961 Amendments (see §§ 783.23 and 783.26). Although...

  17. 12 CFR 931.3 - Minimum investment in capital stock.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Minimum investment in capital stock. 931.3... CAPITAL STANDARDS FEDERAL HOME LOAN BANK CAPITAL STOCK § 931.3 Minimum investment in capital stock. (a) A Bank shall require each member to maintain a minimum investment in the capital stock of the Bank, both...

  18. Current limitations and challenges in nanowaste detection, characterisation and monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Part, Florian; Zecha, Gudrun [Department of Water-Atmosphere-Environment, University of Natural Resources and Life Sciences, Institute of Waste Management, Muthgasse 107, 1190 Vienna (Austria); Causon, Tim [Department of Chemistry, Division of Analytical Chemistry, University of Natural Resources and Life Sciences, Muthgasse 18, 1190 Vienna (Austria); Sinner, Eva-Kathrin [Department of Nanobiotechnology, Institute for Synthetic Bioarchitectures, University of Natural Resources and Life Sciences, Muthgasse 11/II, 1190 Vienna (Austria); Huber-Humer, Marion, E-mail: marion.huber-humer@boku.ac.at [Department of Water-Atmosphere-Environment, University of Natural Resources and Life Sciences, Institute of Waste Management, Muthgasse 107, 1190 Vienna (Austria)

    2015-09-15

    Highlights: • First review on detection of nanomaterials in complex waste samples. • Focus on nanoparticles in solid, liquid and gaseous waste samples. • Summary of current applicable methods for nanowaste detection and characterisation. • Limitations and challenges of characterisation of nanoparticles in waste. - Abstract: Engineered nanomaterials (ENMs) are already extensively used in diverse consumer products. Along the life cycle of a nano-enabled product, ENMs can be released and subsequently accumulate in the environment. Material flow models also indicate that a variety of ENMs may accumulate in waste streams. Therefore, a new type of waste, so-called nanowaste, is generated when end-of-life ENMs and nano-enabled products are disposed of. In terms of the precautionary principle, environmental monitoring of end-of-life ENMs is crucial to allow assessment of the potential impact of nanowaste on our ecosystem. Trace analysis and quantification of nanoparticulate species is very challenging because of the variety of ENM types that are used in products and low concentrations of nanowaste expected in complex environmental media. In the framework of this paper, challenges in nanowaste characterisation and appropriate analytical techniques which can be applied to nanowaste analysis are summarised. Recent case studies focussing on the characterisation of ENMs in waste streams are discussed. Most studies aim to investigate the fate of nanowaste during incineration, particularly considering aerosol measurements; whereas, detailed studies focusing on the potential release of nanowaste during waste recycling processes are currently not available. In terms of suitable analytical methods, separation techniques coupled to spectrometry-based methods are promising tools to detect nanowaste and determine particle size distribution in liquid waste samples. Standardised leaching protocols can be applied to generate soluble fractions stemming from solid wastes, while

  19. Impact limiter retention using a tape joint

    International Nuclear Information System (INIS)

    Gonzales, A.; Eakes, R.G.

    1986-01-01

    The Beneficial Uses Shipping System (BUSS) Cask employs polyurethane foam impact limiters that fit onto the ends of the cask. A foam impact limiter takes energy out of a system during a hypothetical accident condition by allowing foam crush and large deformations to occur. This, in turn, precludes high stresses or deformations from occurring to the cask. Because of the need to transmit significant amounts of heat to the environment, the BUSS cask impact limiters were designed to shield a minimum amount of the cask surface area. With this design impact limiter retention after the initial impact resulting from the 9 meter regulatory drops becomes a concern. Retention is essential to ensure the cask does not experience higher stresses during any secondary or rebound effects without impact limiters than it does during the 9 meter regulatory drop with impact limiters in place

  20. Minimum-Cost Reachability for Priced Timed Automata

    DEFF Research Database (Denmark)

    Behrmann, Gerd; Fehnker, Ansgar; Hune, Thomas Seidelin

    2001-01-01

    This paper introduces the model of linearly priced timed automata as an extension of timed automata, with prices on both transitions and locations. For this model we consider the minimum-cost reachability problem: i.e. given a linearly priced timed automaton and a target state, determine...... the minimum cost of executions from the initial state to the target state. This problem generalizes the minimum-time reachability problem for ordinary timed automata. We prove decidability of this problem by offering an algorithmic solution, which is based on a combination of branch-and-bound techniques...... and a new notion of priced regions. The latter allows symbolic representation and manipulation of reachable states together with the cost of reaching them....

  1. Is the minimum enough? Affordability of a nutritious diet for minimum wage earners in Nova Scotia (2002-2012).

    Science.gov (United States)

    Newell, Felicia D; Williams, Patricia L; Watt, Cynthia G

    2014-05-09

    This paper aims to assess the affordability of a nutritious diet for households earning minimum wage in Nova Scotia (NS) from 2002 to 2012 using an economic simulation that includes food costing and secondary data. The cost of the National Nutritious Food Basket (NNFB) was assessed with a stratified, random sample of grocery stores in NS during six time periods: 2002, 2004/2005, 2007, 2008, 2010 and 2012. The NNFB's cost was factored into affordability scenarios for three different household types relying on minimum wage earnings: a household of four; a lone mother with three children; and a lone man. Essential monthly living expenses were deducted from monthly net incomes using methods that were standardized from 2002 to 2012 to determine whether adequate funds remained to purchase a basic nutritious diet across the six time periods. A 79% increase to the minimum wage in NS has resulted in a decrease in the potential deficit faced by each household scenario in the period examined. However, the household of four and the lone mother with three children would still face monthly deficits ($44.89 and $496.77, respectively, in 2012) if they were to purchase a nutritiously sufficient diet. As a social determinant of health, risk of food insecurity is a critical public health issue for low wage earners. While it is essential to increase the minimum wage in the short term, adequately addressing income adequacy in NS and elsewhere requires a shift in thinking from a focus on minimum wage towards more comprehensive policies ensuring an adequate livable income for everyone.

  2. Employment Effects of Minimum and Subminimum Wages. Recent Evidence.

    Science.gov (United States)

    Neumark, David

    Using a specially constructed panel data set on state minimum wage laws and labor market conditions, Neumark and Wascher (1992) presented evidence that countered the claim that minimum wages could be raised with no cost to employment. They concluded that estimates indicating that minimum wages reduced employment on the order of 1-2 percent for a…

  3. Minimum Wage Effects on Educational Enrollments in New Zealand

    Science.gov (United States)

    Pacheco, Gail A.; Cruickshank, Amy A.

    2007-01-01

    This paper empirically examines the impact of minimum wages on educational enrollments in New Zealand. A significant reform to the youth minimum wage since 2000 has resulted in some age groups undergoing a 91% rise in their real minimum wage over the last 10 years. Three panel least squares multivariate models are estimated from a national sample…

  4. Zero forcing parameters and minimum rank problems

    NARCIS (Netherlands)

    Barioli, F.; Barrett, W.; Fallat, S.M.; Hall, H.T.; Hogben, L.; Shader, B.L.; Driessche, van den P.; Holst, van der H.

    2010-01-01

    The zero forcing number Z(G), which is the minimum number of vertices in a zero forcing set of a graph G, is used to study the maximum nullity/minimum rank of the family of symmetric matrices described by G. It is shown that for a connected graph of order at least two, no vertex is in every zero

  5. Minimum bias measurement at 13 TeV

    CERN Document Server

    Orlando, Nicola; The ATLAS collaboration

    2017-01-01

    The modelling of Minimum Bias (MB) is a crucial ingredient to learn about the description of soft QCD processes and to simulate the environment at the LHC with many concurrent pp interactions (pile-up). We summarise the ATLAS minimum bias measurements with proton-proton collision at 13 TeV center-of-mass-energy at the Large Hadron Collider.

  6. Minimum airflow reset of single-duct VAV terminal boxes

    Science.gov (United States)

    Cho, Young-Hum

    Single duct Variable Air Volume (VAV) systems are currently the most widely used type of HVAC system in the United States. When installing such a system, it is critical to determine the minimum airflow set point of the terminal box, as an optimally selected set point will improve the level of thermal comfort and indoor air quality (IAQ) while at the same time lower overall energy costs. In principle, this minimum rate should be calculated according to the minimum ventilation requirement based on ASHRAE standard 62.1 and maximum heating load of the zone. Several factors must be carefully considered when calculating this minimum rate. Terminal boxes with conventional control sequences may result in occupant discomfort and energy waste. If the minimum rate of airflow is set too high, the AHUs will consume excess fan power, and the terminal boxes may cause significant simultaneous room heating and cooling. At the same time, a rate that is too low will result in poor air circulation and indoor air quality in the air-conditioned space. Currently, many scholars are investigating how to change the algorithm of the advanced VAV terminal box controller without retrofitting. Some of these controllers have been found to effectively improve thermal comfort, indoor air quality, and energy efficiency. However, minimum airflow set points have not yet been identified, nor has controller performance been verified in confirmed studies. In this study, control algorithms were developed that automatically identify and reset terminal box minimum airflow set points, thereby improving indoor air quality and thermal comfort levels, and reducing the overall rate of energy consumption. A theoretical analysis of the optimal minimum airflow and discharge air temperature was performed to identify the potential energy benefits of resetting the terminal box minimum airflow set points. Applicable control algorithms for calculating the ideal values for the minimum airflow reset were developed and

  7. Predicting Minimum Control Speed on the Ground (VMCG) and Minimum Control Airspeed (VMCA) of Engine Inoperative Flight Using Aerodynamic Database and Propulsion Database Generators

    Science.gov (United States)

    Hadder, Eric Michael

    There are many computer aided engineering tools and software used by aerospace engineers to design and predict specific parameters of an airplane. These tools help a design engineer predict and calculate such parameters such as lift, drag, pitching moment, takeoff range, maximum takeoff weight, maximum flight range and much more. However, there are very limited ways to predict and calculate the minimum control speeds of an airplane in engine inoperative flight. There are simple solutions, as well as complicated solutions, yet there is neither standard technique nor consistency throughout the aerospace industry. To further complicate this subject, airplane designers have the option of using an Automatic Thrust Control System (ATCS), which directly alters the minimum control speeds of an airplane. This work addresses this issue with a tool used to predict and calculate the Minimum Control Speed on the Ground (VMCG) as well as the Minimum Control Airspeed (VMCA) of any existing or design-stage airplane. With simple line art of an airplane, a program called VORLAX is used to generate an aerodynamic database used to calculate the stability derivatives of an airplane. Using another program called Numerical Propulsion System Simulation (NPSS), a propulsion database is generated to use with the aerodynamic database to calculate both VMCG and VMCA. This tool was tested using two airplanes, the Airbus A320 and the Lockheed Martin C130J-30 Super Hercules. The A320 does not use an Automatic Thrust Control System (ATCS), whereas the C130J-30 does use an ATCS. The tool was able to properly calculate and match known values of VMCG and VMCA for both of the airplanes. The fact that this tool was able to calculate the known values of VMCG and VMCA for both airplanes means that this tool would be able to predict the VMCG and VMCA of an airplane in the preliminary stages of design. This would allow design engineers the ability to use an Automatic Thrust Control System (ATCS) as part

  8. Experimental detection of domain wall propagation above the Walker field

    International Nuclear Information System (INIS)

    Kondou, Kouta; Chiba, Daichi; Kobayashi, Kensuke; Ono, Teruo; Ohshima, Norikazu; Kasai, Shinya

    2012-01-01

    The domain wall (DW) velocity above the Walker field drops abruptly with increasing magnetic field, because of the so-called Walker breakdown, where the DW moves with a precessional mode. On applying the higher field, the DW velocity again starts to increase gradually. We report the DW propagation around this local minimum regime in detail, investigated through the time-resolved electrical detection technique, with a magnetic tunnel junction. Just above the Walker field, we succeeded in detecting the precessional motion of the DW in a real-time regime, while a different mode appeared around the local minimum of the DW velocity. (paper)

  9. Completely boundary-free minimum and maximum principles for neutron transport and their least-squares and Galerkin equivalents

    International Nuclear Information System (INIS)

    Ackroyd, R.T.

    1982-01-01

    Some minimum and maximum variational principles for even-parity neutron transport are reviewed and the corresponding principles for odd-parity transport are derived by a simple method to show why the essential boundary conditions associated with these maximum principles have to be imposed. The method also shows why both the essential and some of the natural boundary conditions associated with these minimum principles have to be imposed. These imposed boundary conditions for trial functions in the variational principles limit the choice of the finite element used to represent trial functions. The reasons for the boundary conditions imposed on the principles for even- and odd-parity transport point the way to a treatment of composite neutron transport, for which completely boundary-free maximum and minimum principles are derived from a functional identity. In general a trial function is used for each parity in the composite neutron transport, but this can be reduced to one without any boundary conditions having to be imposed. (author)

  10. Minimum wall pressure coefficient of orifice plate energy dissipater

    Directory of Open Access Journals (Sweden)

    Wan-zheng Ai

    2015-01-01

    Full Text Available Orifice plate energy dissipaters have been successfully used in large-scale hydropower projects due to their simple structure, convenient construction procedure, and high energy dissipation ratio. The minimum wall pressure coefficient of an orifice plate can indirectly reflect its cavitation characteristics: the lower the minimum wall pressure coefficient is, the better the ability of the orifice plate to resist cavitation damage is. Thus, it is important to study the minimum wall pressure coefficient of the orifice plate. In this study, this coefficient and related parameters, such as the contraction ratio, defined as the ratio of the orifice plate diameter to the flood-discharging tunnel diameter; the relative thickness, defined as the ratio of the orifice plate thickness to the tunnel diameter; and the Reynolds number of the flow through the orifice plate, were theoretically analyzed, and their relationships were obtained through physical model experiments. It can be concluded that the minimum wall pressure coefficient is mainly dominated by the contraction ratio and relative thickness. The lower the contraction ratio and relative thickness are, the larger the minimum wall pressure coefficient is. The effects of the Reynolds number on the minimum wall pressure coefficient can be neglected when it is larger than 105. An empirical expression was presented to calculate the minimum wall pressure coefficient in this study.

  11. Intrinsic spatial resolution limitations due to differences between positron emission position and annihilation detection localization

    International Nuclear Information System (INIS)

    Perez, Pedro; Malano, Francisco; Valente, Mauro

    2012-01-01

    Since its successful implementation for clinical diagnostic, positron emission tomography (PET) represents the most promising medical imaging technique. The recent major growth of PET imaging is mainly due to its ability to trace the biologic pathways of different compounds in the patient's body, assuming the patient can be labeled with some PET isotope. Regardless of the type of isotope, the PET imaging method is based on the detection of two 511-keV gamma photons being emitted in opposite directions, with almost 180 deg between them, as a consequence of electron-positron annihilation. Therefore, this imaging method is intrinsically limited by random uncertainties in spatial resolutions, related with differences between the actual position of positron emission and the location of the detected annihilation. This study presents an approach with the Monte Carlo method to analyze the influence of this effect on different isotopes of potential implementation in PET. (author)

  12. Breath Analysis Using Laser Spectroscopic Techniques: Breath Biomarkers, Spectral Fingerprints, and Detection Limits

    Directory of Open Access Journals (Sweden)

    Peeyush Sahay

    2009-10-01

    Full Text Available Breath analysis, a promising new field of medicine and medical instrumentation, potentially offers noninvasive, real-time, and point-of-care (POC disease diagnostics and metabolic status monitoring. Numerous breath biomarkers have been detected and quantified so far by using the GC-MS technique. Recent advances in laser spectroscopic techniques and laser sources have driven breath analysis to new heights, moving from laboratory research to commercial reality. Laser spectroscopic detection techniques not only have high-sensitivity and high-selectivity, as equivalently offered by the MS-based techniques, but also have the advantageous features of near real-time response, low instrument costs, and POC function. Of the approximately 35 established breath biomarkers, such as acetone, ammonia, carbon dioxide, ethane, methane, and nitric oxide, 14 species in exhaled human breath have been analyzed by high-sensitivity laser spectroscopic techniques, namely, tunable diode laser absorption spectroscopy (TDLAS, cavity ringdown spectroscopy (CRDS, integrated cavity output spectroscopy (ICOS, cavity enhanced absorption spectroscopy (CEAS, cavity leak-out spectroscopy (CALOS, photoacoustic spectroscopy (PAS, quartz-enhanced photoacoustic spectroscopy (QEPAS, and optical frequency comb cavity-enhanced absorption spectroscopy (OFC-CEAS. Spectral fingerprints of the measured biomarkers span from the UV to the mid-IR spectral regions and the detection limits achieved by the laser techniques range from parts per million to parts per billion levels. Sensors using the laser spectroscopic techniques for a few breath biomarkers, e.g., carbon dioxide, nitric oxide, etc. are commercially available. This review presents an update on the latest developments in laser-based breath analysis.

  13. Potentials and Limitations of Real-Time Elastography for Prostate Cancer Detection: A Whole-Mount Step Section Analysis

    Directory of Open Access Journals (Sweden)

    Daniel Junker

    2012-01-01

    Full Text Available Objectives. To evaluate prostate cancer (PCa detection rates of real-time elastography (RTE in dependence of tumor size, tumor volume, localization and histological type. Materials and Methods. Thirdy-nine patients with biopsy proven PCa underwent RTE before radical prostatectomy (RPE to assess prostate tissue elasticity, and hard lesions were considered suspicious for PCa. After RPE, the prostates were prepared as whole-mount step sections and were compared with imaging findings for analyzing PCa detection rates. Results. RTE detected 6/62 cancer lesions with a maximum diameter of 0–5 mm (9.7%, 10/37 with a maximum diameter of 6–10 mm (27%, 24/34 with a maximum diameter of 11–20 20 mm (70.6%, 14/14 with a maximum diameter of >20 mm (100% and 40/48 with a volume ≥0.2 cm3 (83.3%. Regarding cancer lesions with a volume ≥ 0.2 cm³ there was a significant difference in PCa detection rates between Gleason scores with predominant Gleason pattern 3 compared to those with predominant Gleason pattern 4 or 5 (75% versus 100%; P=0.028. Conclusions. RTE is able to detect PCa of significant tumor volume and of predominant Gleason pattern 4 or 5 with high confidence, but is of limited value in the detection of small cancer lesions.

  14. Future changes over the Himalayas: Maximum and minimum temperature

    Science.gov (United States)

    Dimri, A. P.; Kumar, D.; Choudhary, A.; Maharana, P.

    2018-03-01

    An assessment of the projection of minimum and maximum air temperature over the Indian Himalayan region (IHR) from the COordinated Regional Climate Downscaling EXperiment- South Asia (hereafter, CORDEX-SA) regional climate model (RCM) experiments have been carried out under two different Representative Concentration Pathway (RCP) scenarios. The major aim of this study is to assess the probable future changes in the minimum and maximum climatology and its long-term trend under different RCPs along with the elevation dependent warming over the IHR. A number of statistical analysis such as changes in mean climatology, long-term spatial trend and probability distribution function are carried out to detect the signals of changes in climate. The study also tries to quantify the uncertainties associated with different model experiments and their ensemble in space, time and for different seasons. The model experiments and their ensemble show prominent cold bias over Himalayas for present climate. However, statistically significant higher warming rate (0.23-0.52 °C/decade) for both minimum and maximum air temperature (Tmin and Tmax) is observed for all the seasons under both RCPs. The rate of warming intensifies with the increase in the radiative forcing under a range of greenhouse gas scenarios starting from RCP4.5 to RCP8.5. In addition to this, a wide range of spatial variability and disagreements in the magnitude of trend between different models describes the uncertainty associated with the model projections and scenarios. The projected rate of increase of Tmin may destabilize the snow formation at the higher altitudes in the northern and western parts of Himalayan region, while rising trend of Tmax over southern flank may effectively melt more snow cover. Such combined effect of rising trend of Tmin and Tmax may pose a potential threat to the glacial deposits. The overall trend of Diurnal temperature range (DTR) portrays increasing trend across entire area with

  15. The Impact of a City-Level Minimum-Wage Policy on Supermarket Food Prices in Seattle-King County.

    Science.gov (United States)

    Otten, Jennifer J; Buszkiewicz, James; Tang, Wesley; Aggarwal, Anju; Long, Mark; Vigdor, Jacob; Drewnowski, Adam

    2017-09-09

    Background : Many states and localities throughout the U.S. have adopted higher minimum wages. Higher labor costs among low-wage food system workers could result in higher food prices. Methods : Using a market basket of 106 foods, food prices were collected at affected chain supermarket stores in Seattle and same-chain unaffected stores in King County (n = 12 total, six per location). Prices were collected at 1 month pre- (March 2015) and 1-month post-policy enactment (May 2015), then again 1-year post-policy enactment (May 2016). Unpaired t-tests were used to detect price differences by location at fixed time while paired t-tests were used to detect price difference across time with fixed store chain. A multi-level, linear differences-in-differences model, was used to detect the changes in the average market basket item food prices over time across regions, overall and by food group. Results : There were no significant differences in overall market basket or item-level costs at one-month (-$0.01, SE = 0.05, p = 0.884) or one-year post-policy enactment (-$0.02, SE = 0.08, p = 0.772). No significant increases were observed by food group. Conclusions : There is no evidence of change in supermarket food prices by market basket or increase in prices by food group in response to the implementation of Seattle's minimum wage ordinance.

  16. 76 FR 15368 - Minimum Security Devices and Procedures

    Science.gov (United States)

    2011-03-21

    ... DEPARTMENT OF THE TREASURY Office of Thrift Supervision Minimum Security Devices and Procedures... concerning the following information collection. Title of Proposal: Minimum Security Devices and Procedures... security devices and procedures to discourage robberies, burglaries, and larcenies, and to assist in the...

  17. What is the minimum value of the safety factor on the magnetic axis

    International Nuclear Information System (INIS)

    Bussac, M.N.; Pellat, R.; Edery, D.; Soule, J.L.

    This paper is presented in the following way: in chapter 2 the main stability properties in the vicinity of the magnetic axis with respect to the localized modes is recalled. The possibility of decreasing the minimum value of the safety factor q below unity, without violating Mercier's criterion is emphasized. In chapter 3 the ideal internal kink in cylindrical geometry for non-circular cross-sections is studied. The main findings are the small destabilizing effect of an elliptical deformation and the larger stabilizing effect of a triangular deformation. In chapter 4 the previous analysis is completed by toroidal corrections and the complete result for the ideal internal kink for circular magnetic surfaces is given. This mode may be stable in toroidal geometry provided the minimum value of q remains larger than 1/2. In chapter 5 the resistive internal kink and its collisionless high temperature limit is discussed. Toroidal effects and non-linear effects in the non-linear development of the tearing modes are compared

  18. Comparison of sensitivities and detection limits between direct excitation and secondary excitation modes in energy dispersive x-ray fluorescence analysis

    International Nuclear Information System (INIS)

    Artz, B.E.; Short, M.A.

    1976-01-01

    A comparison was made between the direct tube excitation mode and the secondary target excitation mode using a Kevex 0810 energy dispersive x-ray fluorescence system. Relative sensitivities and detection limits were determined with two system configurations. The first configuration used a standard, high power, x-ray fluorescence tube to directly excite the specimen. Several x-ray tubes, including chromium, molybdenum, and tungsten, both filtered and not filtered, were employed. The second configuration consisted of using the x-ray tube to excite a secondary target which in turn excited the specimen. Appropriate targets were compared to the direct excitation results. Relative sensitivities and detection limits were determined for K-series lines for elements from magnesium to barium contained in a low atomic number matrix and in a high atomic number matrix

  19. Scheme for efficient extraction of low-frequency signal beyond the quantum limit by frequency-shift detection.

    Science.gov (United States)

    Yang, R G; Zhang, J; Zhai, Z H; Zhai, S Q; Liu, K; Gao, J R

    2015-08-10

    Low-frequency (Hz~kHz) squeezing is very important in many schemes of quantum precision measurement. But it is more difficult than that at megahertz-frequency because of the introduction of laser low-frequency technical noise. In this paper, we propose a scheme to obtain a low-frequency signal beyond the quantum limit from the frequency comb in a non-degenerate frequency and degenerate polarization optical parametric amplifier (NOPA) operating below threshold with type I phase matching by frequency-shift detection. Low-frequency squeezing immune to laser technical noise is obtained by a detection system with a local beam of two-frequency intense laser. Furthermore, the low-frequency squeezing can be used for phase measurement in Mach-Zehnder interferometer, and the signal-to-noise ratio (SNR) can be enhanced greatly.

  20. Experimental study to optimize time resolution and detection limit of online 222Rn-in-water measurements

    International Nuclear Information System (INIS)

    Just, G.; Freyer, K.; Treutler, H.C.; Philipsborn, H. von

    2001-01-01

    The possibility to detect short-term variations of the activity concentration of 222 Rn in water by online monitoring with temporal resolutions of a few minutes and a lower limit of detection of about 1 Bq/l enhances the applicability of such measurements. New applications would be possible in the field of hydro-geology in which Rn is used as tracer gas, the monitoring of pumping procedures, for the study of exchange processes during groundwater sampling and for various applications with geophysical effects. A suitable, simple method is the measuring principle proposed by Surbeck (Fribourg) some years ago which is based on the separation of air and water by a diffusion membrane. Process parameters enhancing the time resolution of the method as well as the efficiency of different radon detectors have been studied. (orig.) [de

  1. Effect of sample matrix composition on INAA sample weights, measurement precisions, limits of detection, and optimum conditions

    International Nuclear Information System (INIS)

    Guinn, V.P.; Nakazawa, L.; Leslie, J.

    1984-01-01

    The instrumental neutron activation analysis (INAA) Advance Prediction Computer Program (APCP) is extremely useful in guiding one to optimum subsequent experimental analyses of samples of all types of matrices. By taking into account the contributions to the cumulative Compton-continuum levels from all significant induced gamma-emitting radionuclides, it provides good INAA advance estimates of detectable photopeaks, measurement precisions, concentration lower limits of detection (LOD's) and optimum irradiation/decay/counting conditions - as well as of the very important maximum allowable sample size for each set of conditions calculated. The usefulness and importance of the four output parameters cited in the title are discussed using the INAA APCP outputs for NBS SRM-1632 Coal as the example

  2. Determination of chromium(VI) in water by PIXE analysis using ion exchange paper. Limit of detection and interference by coexisting anions

    International Nuclear Information System (INIS)

    Thomyasirigul, Sureerat; Fukuda, Hitoshi; Hasegawa, Jun; Oguri, Yoshiyuki

    2009-01-01

    Concerning the PIXE analysis of Cr(VI) in water using ion-exchange filters, the limit of detection (LOD) and the influence of matrix anions were investigated. In order to look for the experimental condition for obtaining the minimum LOD, we measured the Cr-Kα X-ray counts and background counts under the Kα X-ray peak as a function of the incident proton energy and the thickness of the Mylar absorber foil in front of the detector. To investigate the interference by coexisting anions, each of PO 4 3- , SO 4 2- , NO 3 - , Cl - , and F - ions and Cr(VI) ions were mixed in aqueous solutions and adsorbed on DE81-DEAE cellulose paper, a weakly basic anion exchanger with diethylaminoethyl functional groups. Then the filter samples were measured by PIXE using 2.5 MeV proton beams. We obtained a LOD of 0.16 μg or 8 ppb for 20 mL samples at a proton energy of 2.5 MeV and a Mylar film thickness of 50 or 100 μm. The experimental results on the mixed solutions indicated that NO 3 - , Cl - , and F - as coexisting ions didn't interfere significantly with determination of a 50 μg/L Cr(VI) concentration for 40 mL total solution volume, despite the total amount of anions was about 90% of ion exchange capacity of a filter. On the other hand, slight interferences by PO 4 3- ions were observed. However, under the same condition, we found that if the total amount of SO 4 2- ions was higher than 20% of ion exchange capacity, they induced significant interferences in determining Cr(VI). (author)

  3. [Long-term outcome of vitrectomy combined with internal limiting membrane peeling for idiopathic macular holes].

    Science.gov (United States)

    Yamamoto, Kaori; Hori, Sadao

    2011-01-01

    To elucidate the long-term outcome of internal limiting membrane (ILM) peeling on visual function during vitrectomy for idiopathic macular holes using scanning laser ophthalmoscope (SLO) microperimetry. Prospective uncontrolled study. We studied 31 eyes (29 patients) with idiopathic macular holes. All patients underwent vitrectomy with ILM peeling. The SLO microperimetry was performed preoperatively, and once a year for 3 years postoperatively to detect scotomas in and around the macular holes, and both within and in close vicinity to the areas of ILM peeling. Closure of macular holes after one surgery was confirmed in all cases except for 2 with second surgery. The visual acuity by logarithmic minimum angle of resolution (logMAR) averaged 0.71 +/- 0.36 before surgery, 0.23 +/- 0.31 one year, 0.14 +/- 0.27 two years and 0.12 +/- 0.26 three years after surgery. There was significant improvement up to 2 years after the surgery. All scotomas detected before surgery in the holes, and 77.4% of those detected around the holes decreased gradually. No scotomas were detected in or around the area of ILM peeling either before or after surgery. ILM peeling in vitrectomy for idiopathic macular holes successfully improved visual acuity and did not influence retinal sensitivity in and around the area of ILM peeling. The scotomas detected in and around the holes before surgery gradually reduced or disappeared.

  4. 76 FR 30243 - Minimum Security Devices and Procedures

    Science.gov (United States)

    2011-05-24

    ... DEPARTMENT OF THE TREASURY Office of Thrift Supervision Minimum Security Devices and Procedures.... Title of Proposal: Minimum Security Devices and Procedures. OMB Number: 1550-0062. Form Number: N/A... respect to the installation, maintenance, and operation of security devices and procedures to discourage...

  5. Does increasing the minimum wage reduce poverty in developing countries?

    OpenAIRE

    Gindling, T. H.

    2014-01-01

    Do minimum wage policies reduce poverty in developing countries? It depends. Raising the minimum wage could increase or decrease poverty, depending on labor market characteristics. Minimum wages target formal sector workers—a minority of workers in most developing countries—many of whom do not live in poor households. Whether raising minimum wages reduces poverty depends not only on whether formal sector workers lose jobs as a result, but also on whether low-wage workers live in poor househol...

  6. Discovery of X-Ray Emission from the Crab Pulsar at Pulse Minimum

    Science.gov (United States)

    Tennant, Allyn F.; Becker, Werner; Juda, Michael; Elsner, Ronald F.; Kolodziejczak, Jeffery J.; Murray, Stephen S.; ODell, Stephen L.; Paerels, Frits; Swartz, Douglas A.

    2001-01-01

    The Chandra X-Ray Observatory observed the Crab pulsar using the Low-Energy Transmission Grating with the High-Resolution Camera. Time-resolved zeroth-order images reveal that the pulsar emits X-rays at all pulse phases. Analysis of the flux at minimum - most likely non-thermal in origin - places an upper limit (T(sub infinity) < 2.1 MK) on the surface temperature of the underlying neutron star. In addition, analysis of the pulse profile establishes that the error in the Chandra-determined absolute time is quite small, -0.2 +/- 0.1 ms.

  7. The SME gauge sector with minimum length

    Science.gov (United States)

    Belich, H.; Louzada, H. L. C.

    2017-12-01

    We study the gauge sector of the Standard Model Extension (SME) with the Lorentz covariant deformed Heisenberg algebra associated to the minimum length. In order to find and estimate corrections, we clarify whether the violation of Lorentz symmetry and the existence of a minimum length are independent phenomena or are, in some way, related. With this goal, we analyze the dispersion relations of this theory.

  8. The SME gauge sector with minimum length

    Energy Technology Data Exchange (ETDEWEB)

    Belich, H.; Louzada, H.L.C. [Universidade Federal do Espirito Santo, Departamento de Fisica e Quimica, Vitoria, ES (Brazil)

    2017-12-15

    We study the gauge sector of the Standard Model Extension (SME) with the Lorentz covariant deformed Heisenberg algebra associated to the minimum length. In order to find and estimate corrections, we clarify whether the violation of Lorentz symmetry and the existence of a minimum length are independent phenomena or are, in some way, related. With this goal, we analyze the dispersion relations of this theory. (orig.)

  9. Akibat Hukum Bagi Bank Bila Kewajiban Modal Inti Minimum Tidak Terpenuhi

    Directory of Open Access Journals (Sweden)

    Indira Retno Aryatie

    2012-02-01

    Full Text Available As an implementation of the Indonesian Banking Architecture policy, the government issues Bank Indonesia Regulation No. 9/16/ PBI/2007 on Minimum Tier One Capital that increases the minimum capital to 100 billion rupiah. This writing discusses the legal complication that a bank will face should it fail to fulfil the minimum ratio. Sebagai tindak lanjut dari kebijakan Arsitektur Perbankan Indonesia, pemerintah mengeluarkan Peraturan Bank Indonesia 9/16/PBI/2007 tentang Kewajiban Modal Inti Minimum Bank yang menaikkan modal inti minimum bank umum menjadi 100 miliar rupiah. Tulisan ini membahas akibat hukum yang akan dialami bank bila kewajiban modal minimum tersebut gagal dipenuhi.

  10. The impact of minimum wage adjustments on Vietnamese wage inequality

    DEFF Research Database (Denmark)

    Hansen, Henrik; Rand, John; Torm, Nina

    Using Vietnamese Labour Force Survey data we analyse the impact of minimum wage changes on wage inequality. Minimum wages serve to reduce local wage inequality in the formal sectors by decreasing the gap between the median wages and the lower tail of the local wage distributions. In contrast, local...... wage inequality is increased in the informal sectors. Overall, the minimum wages decrease national wage inequality. Our estimates indicate a decrease in the wage distribution Gini coefficient of about 2 percentage points and an increase in the 10/50 wage ratio of 5-7 percentage points caused...... by the adjustment of the minimum wages from 2011to 2012 that levelled the minimum wage across economic sectors....

  11. A factor analysis to detect factors influencing building national brand

    Directory of Open Access Journals (Sweden)

    Naser Azad

    Full Text Available Developing a national brand is one of the most important issues for development of a brand. In this study, we present factor analysis to detect the most important factors in building a national brand. The proposed study uses factor analysis to extract the most influencing factors and the sample size has been chosen from two major auto makers in Iran called Iran Khodro and Saipa. The questionnaire was designed in Likert scale and distributed among 235 experts. Cronbach alpha is calculated as 84%, which is well above the minimum desirable limit of 0.70. The implementation of factor analysis provides six factors including “cultural image of customers”, “exciting characteristics”, “competitive pricing strategies”, “perception image” and “previous perceptions”.

  12. Improved detection limit in rapid detection of human enterovirus 71 and coxsackievirus A16 by a novel reverse transcription-isothermal multiple-self-matching-initiated amplification assay.

    Science.gov (United States)

    Ding, Xiong; Nie, Kai; Shi, Lei; Zhang, Yong; Guan, Li; Zhang, Dan; Qi, Shunxiang; Ma, Xuejun

    2014-06-01

    Rapid detection of human enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) is important in the early phase of hand-foot-and-mouth disease (HFMD). In this study, we developed and evaluated a novel reverse transcription-isothermal multiple-self-matching-initiated amplification (RT-IMSA) assay for the rapid detection of EV71 and CVA16 by use of reverse transcriptase, together with a strand displacement DNA polymerase. Real-time RT-IMSA assays using a turbidimeter and visual RT-IMSA assays to detect EV71 and CVA16 were established and completed in 1 h, and the reported corresponding real-time reverse transcription-loop-mediated isothermal amplification (RT-LAMP) assays targeting the same regions of the VP1 gene were adopted as parallel tests. Through testing VP1 RNAs transcribed in vitro, the real-time RT-IMSA assays exhibited better linearity of quantification, with R(2) values of 0.952 (for EV71) and 0.967 (for CVA16), than the real-time RT-LAMP assays, which had R(2) values of 0.803 (for EV71) and 0.904 (for CVA16). Additionally, the detection limits of the real-time RT-IMSA assays (approximately 937 for EV71 and 67 for CVA16 copies/reaction) were higher than those of real-time RT-LAMP assays (approximately 3,266 for EV71 and 430 for CVA16 copies/reaction), and similar results were observed in the visual RT-IMSA assays. The new approaches also possess high specificities for the corresponding targets, with no cross-reactivity observed. In clinical assessment, compared to commercial reverse transcription-quantitative PCR (qRT-PCR) kits, the diagnostic sensitivities of the real-time RT-IMSA assays (96.4% for EV71 and 94.6% for CVA16) were higher than those of the real-time RT-LAMP assays (91.1% for EV71 and 90.8% for CVA16). The visual RT-IMSA assays also exhibited the same results. In conclusion, this proof-of-concept study suggests that the novel RT-IMSA assay is superior to the RT-LAMP assay in terms of detection limit and has the potential to rapidly detect EV71

  13. The possibility of the dose limitation system application non-ionizing radiation protection

    International Nuclear Information System (INIS)

    Ranisavljevic, M., Markovic, S.

    1997-01-01

    Modern conception of the ionizing radiation protection is based on Dose Limitation System. In the base of every human decision lies compromise. Balance between positive and negative factors, benefit and detriment, profit and expense includes the decision about possibilities for realization any defined radiation practice. The optimal option for the given value of the varying parameter gives the maximum benefit and the minimum detriment. In radiation protection field, detriment is related with human health or expenses, and varying parameter is level of radiation protection (for example dimensions of the installed shielding). The problem lies in fact that for the given value of the varying shielding parameter the maximum benefit and the minimum detriment are not achievable simultaneously because the greater benefit includes the greater expense. The problems which have to be solved because of introducing Dose Limitation System, in regard to create Modified Dose Limitation System, are presented. (author)

  14. 42 CFR 84.197 - Respirator containers; minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Respirator containers; minimum requirements. 84.197... Cartridge Respirators § 84.197 Respirator containers; minimum requirements. Respirators shall be equipped with a substantial, durable container bearing markings which show the applicant's name, the type and...

  15. 42 CFR 84.174 - Respirator containers; minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Respirator containers; minimum requirements. 84.174... Air-Purifying Particulate Respirators § 84.174 Respirator containers; minimum requirements. (a) Except..., durable container bearing markings which show the applicant's name, the type of respirator it contains...

  16. Left ventricular time volume curve analysis in the detection of limited ischaemic heart disease

    International Nuclear Information System (INIS)

    Liechtenstein, M.; Blanchett, W.; Andrews, J.; Hunt, D.

    1982-01-01

    The aim of the study was to determine whether limited coronary artery disease (CAD) could be accurately detected using the Cardiac Gated Blood Pool (CGBP) scan with exercise. Regional left ventricular time volume curves (RLTVD) were generated from 52 studies (46 patients: 22 normals, 24 abnormals). The parameters assessed both globally and regionally and at rest (R) and exercise (Ex) were: (1) the ejection fraction (EF) (2) the change in ejection fraction from R to Ex (δEF) (3) an early contraction index (ECI) (4) a maximal emptying index (DR) and (5) a maximal refilling index (AR). After careful analysis of these parameters it was decided that our diagnostic criteria would rely on the following: (1) the EF at R and Ex (2) the δ EF (3) the ECI at Ex (4) the AR at Ex This study showed that both the sensitivity and the specificity of the CGBP scan can be improved considerably with the inclusion of RLTVC from the levels obtained when the EF parameters alone are considered. It is possible with this technique to accurately diagnose limited CAD. (Author)

  17. A highly sensitive and selective aptamer-based colorimetric sensor for the rapid detection of PCB 77.

    Science.gov (United States)

    Cheng, Ruojie; Liu, Siyao; Shi, Huijie; Zhao, Guohua

    2018-01-05

    A highly sensitive, specific and simple colorimetric sensor based on aptamer was established for the detection of polychlorinated biphenyls (PCB 77). The use of unmodified gold nanoparticles as a colorimetric probe for aptamer sensors enabled the highly sensitive and selective detection of polychlorinated biphenyls (PCB 77). A linear range of 0.5nM to 900nM was obtained for the colorimetric assay with a minimum detection limit of 0.05nM. In addition, by the methods of circular dichroism, UV and naked eyes, we found that the 35 base fragments retained after cutting 5 bases from the 5 'end of aptamer plays the most significant role in the PCB 77 specific recognition process. We found a novel way to truncated nucleotides to optimize the detection of PCB 77, and the selected nucleotides also could achieve high affinity with PCB 77. At the same time, the efficient detection of the PCB 77 by our colorimetric sensor in the complex environmental water samples was realized, which shows a good application prospect. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Design of a minimum emittance nBA lattice

    Science.gov (United States)

    Lee, S. Y.

    1998-04-01

    An attempt to design a minimum emittance n-bend achromat (nBA) lattice has been made. One distinct feature is that dipoles with two different lengths were used. As a multiple bend achromat, five bend achromat lattices with six superperiod were designed. The obtained emittace is three times larger than the theoretical minimum. Tunes were chosen to avoid third order resonances. In order to correct first and second order chromaticities, eight family sextupoles were placed. The obtained emittance of five bend achromat lattices is almost equal to the minimum emittance of five bend achromat lattice consisting of dipoles with equal length.

  19. Quantum mechanics the theoretical minimum

    CERN Document Server

    Susskind, Leonard

    2014-01-01

    From the bestselling author of The Theoretical Minimum, an accessible introduction to the math and science of quantum mechanicsQuantum Mechanics is a (second) book for anyone who wants to learn how to think like a physicist. In this follow-up to the bestselling The Theoretical Minimum, physicist Leonard Susskind and data engineer Art Friedman offer a first course in the theory and associated mathematics of the strange world of quantum mechanics. Quantum Mechanics presents Susskind and Friedman’s crystal-clear explanations of the principles of quantum states, uncertainty and time dependence, entanglement, and particle and wave states, among other topics. An accessible but rigorous introduction to a famously difficult topic, Quantum Mechanics provides a tool kit for amateur scientists to learn physics at their own pace.

  20. Suspension Array for Multiplex Detection of Eight Fungicide-Resistance Related Alleles in Botrytis cinerea

    Directory of Open Access Journals (Sweden)

    Xin Zhang

    2016-09-01

    Full Text Available A simple and high-throughput assay to detect fungicide resistance is required for large-scale monitoring of the emergence of resistant strains of Botrytis cinerea. Using suspension array technology performed on a Bio-Plex 200 System, we developed a single-tube allele-specific primer extension (ASPE assay that can simultaneously detect eight alleles in one reaction. These eight alleles include E198 and 198A of the β-Tubulin gene (BenA, H272 and 272Y of the Succinate dehydrogenase iron–sulfur subunit gene (SdhB, I365 and 365S of the putative osmosensor histidine kinase gene (BcOS1, and F412 and 412S of the 3-ketoreductase gene (erg27. This assay was first established and optimized with eight plasmid templates containing the DNA sequence variants BenA-E198, BenA-198A, SdhB-H272, SdhB-272Y, BcOS1-I365, BcOS1-365S, erg27-F412, and erg27-412S. Results indicated that none of the probes showed cross-reactivity with one another. The minimum limit of detection for these genotypes was one copy per test. Four mutant plasmids were mixed with 10 ng/μL wild-type genomic DNA in different ratios. Detection sensitivity of mutant loci was 0.45% for BenA-E198A, BcOS1-I365S, and erg27-F412S, and was 4.5% for SdhB-H272Y. A minimum quantity of 0.1 ng of genomic DNA was necessary to obtain reliable results. This is the first reported assay that can simultaneously detect mutations in BenA, SdhB, BcOS1, and erg27.

  1. Suspension Array for Multiplex Detection of Eight Fungicide-Resistance Related Alleles in Botrytis cinerea.

    Science.gov (United States)

    Zhang, Xin; Xie, Fei; Lv, Baobei; Zhao, Pengxiang; Ma, Xuemei

    2016-01-01

    A simple and high-throughput assay to detect fungicide resistance is required for large-scale monitoring of the emergence of resistant strains of Botrytis cinerea . Using suspension array technology performed on a Bio-Plex 200 System, we developed a single-tube allele-specific primer extension assay that can simultaneously detect eight alleles in one reaction. These eight alleles include E198 and 198A of the β-Tubulin gene ( BenA ), H272 and 272Y of the Succinate dehydrogenase iron-sulfur subunit gene ( SdhB) , I365 and 365S of the putative osmosensor histidine kinase gene ( BcOS1 ), and F412 and 412S of the 3-ketoreductase gene ( erg27 ). This assay was first established and optimized with eight plasmid templates containing the DNA sequence variants BenA- E198, BenA- 198A, SdhB- H272, SdhB- 272Y, BcOS1- I365, BcOS1- 365S, erg27 -F412, and erg27 -412S. Results indicated that none of the probes showed cross-reactivity with one another. The minimum limit of detection for these genotypes was one copy per test. Four mutant plasmids were mixed with 10 ng/μL wild-type genomic DNA in different ratios. Detection sensitivity of mutant loci was 0.45% for BenA- E198A, BcOS1- I365S, and erg27 -F412S, and was 4.5% for SdhB- H272Y. A minimum quantity of 0.1 ng of genomic DNA was necessary to obtain reliable results. This is the first reported assay that can simultaneously detect mutations in BenA , SdhB , BcOS1 , and erg27 .

  2. Improved detection limits for phthalates by selective solid-phase micro-extraction

    KAUST Repository

    Zia, Asif I.

    2016-03-30

    Presented research reports on an improved method and enhanced limits of detection for phthalates; a hazardous additive used in the production of plastics by solid-phase micro-extraction (SPME) polymer in comparison to molecularly imprinted solid-phase extraction (MISPE) polymer. The polymers were functionalized on an interdigital capacitive sensor for selective binding of phthalate molecules from a complex mixture of chemicals. Both polymers owned predetermined selectivity by formation of valuable molecular recognition sites for Bis (2-ethylhexyl) phthalate (DEHP). Polymers were immobilized on planar electrochemical sensor fabricated on a single crystal silicon substrate with 500 nm sputtered gold electrodes fabricated using MEMS fabrication techniques. Impedance spectra were obtained using electrochemical impedance spectroscopy (EIS) to determine sample conductance for evaluation of phthalate concentration in the spiked sample solutions with various phthalate concentrations. Experimental results revealed that the ability of SPME polymer to adsorb target molecules on the sensing surface is better than that of MISPE polymer for phthalates in the sensing system. Testing the extracted samples using high performance liquid chromatography with photodiode array detectors validated the results.

  3. Counter-current flow limited CHF in thin rectangular channels

    International Nuclear Information System (INIS)

    Cheng, L.Y.

    1990-01-01

    An analytical expression for counter-current-flow-limitation (CCFL) was used to predict critical heat flux (CHF) for downward flow in thin vertical rectangular channels which are prototypes of coolant channels in test and research nuclear reactors. Top flooding is the mechanism for counter-current flow limited CHF. The CCFL correlation also was used to determine the circulation and flooding-limited CHF. Good agreements were observed between the period the model predictions and data on the CHF for downflow. The minimum CHF for downflow is lower than the flooding-limited CHF and it is predicted to occur at a liquid flow rate higher than that at the flooding limit. 17 refs., 7 figs

  4. Physiological Limits along an Elevational Gradient in a Radiation of Montane Ground Beetles.

    Science.gov (United States)

    Slatyer, Rachel A; Schoville, Sean D

    2016-01-01

    A central challenge in ecology and biogeography is to determine the extent to which physiological constraints govern the geographic ranges of species along environmental gradients. This study tests the hypothesis that temperature and desiccation tolerance are associated with the elevational ranges of 12 ground beetle species (genus Nebria) occurring on Mt. Rainier, Washington, U.S.A. Species from higher elevations did not have greater cold tolerance limits than lower-elevation species (all species ranged from -3.5 to -4.1°C), despite a steep decline in minimum temperature with elevation. Although heat tolerance limits varied among species (from 32.0 to 37.0°C), this variation was not generally associated with the relative elevational range of a species. Temperature gradients and acute thermal tolerance do not support the hypothesis that physiological constraints drive species turnover with elevation. Measurements of intraspecific variation in thermal tolerance limits were not significant for individuals taken at different elevations on Mt. Rainier, or from other mountains in Washington and Oregon. Desiccation resistance was also not associated with a species' elevational distribution. Our combined results contrast with previously-detected latitudinal gradients in acute physiological limits among insects and suggest that other processes such as chronic thermal stress or biotic interactions might be more important in constraining elevational distributions in this system.

  5. Calculation of the minimum critical mass of fissile nuclides

    International Nuclear Information System (INIS)

    Wright, R.Q.; Hopper, Calvin Mitchell

    2008-01-01

    The OB-1 method for the calculation of the minimum critical mass of fissile actinides in metal/water systems was described in a previous paper. A fit to the calculated minimum critical mass data using the extended criticality parameter is the basis of the revised method. The solution density (grams/liter) for the minimum critical mass is also obtained by a fit to calculated values. Input to the calculation consists of the Maxwellian averaged fission and absorption cross sections and the thermal values of nubar. The revised method gives more accurate values than the original method does for both the minimum critical mass and the solution densities. The OB-1 method has been extended to calculate the uncertainties in the minimum critical mass for 12 different fissile nuclides. The uncertainties for the fission and capture cross sections and the estimated nubar uncertainties are used to determine the uncertainties in the minimum critical mass, either in percent or grams. Results have been obtained for U-233, U-235, Pu-236, Pu-239, Pu-241, Am-242m, Cm-243, Cm-245, Cf-249, Cf-251, Cf-253, and Es-254. Eight of these 12 nuclides are included in the ANS-8.15 standard.

  6. 40 CFR Appendix C to Part 425 - Definition and Procedure for the Determination of the Method Detection Limit 1

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Definition and Procedure for the Determination of the Method Detection Limit 1 C Appendix C to Part 425 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS LEATHER TANNING AND FINISHING POINT SOURCE...

  7. 42 CFR 84.134 - Respirator containers; minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Respirator containers; minimum requirements. 84.134... Respirators § 84.134 Respirator containers; minimum requirements. Supplied-air respirators shall be equipped with a substantial, durable container bearing markings which show the applicant's name, the type and...

  8. 42 CFR 84.1134 - Respirator containers; minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Respirator containers; minimum requirements. 84... Combination Gas Masks § 84.1134 Respirator containers; minimum requirements. (a) Except as provided in paragraph (b) of this section each respirator shall be equipped with a substantial, durable container...

  9. 42 CFR 84.74 - Apparatus containers; minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Apparatus containers; minimum requirements. 84.74...-Contained Breathing Apparatus § 84.74 Apparatus containers; minimum requirements. (a) Apparatus may be equipped with a substantial, durable container bearing markings which show the applicant's name, the type...

  10. Minimum K-S estimator using PH-transform technique

    Directory of Open Access Journals (Sweden)

    Somchit Boonthiem

    2016-07-01

    Full Text Available In this paper, we propose an improvement of the Minimum Kolmogorov-Smirnov (K-S estimator using proportional hazards transform (PH-transform technique. The data of experiment is 47 fire accidents data of an insurance company in Thailand. This experiment has two operations, the first operation, we minimize K-S statistic value using grid search technique for nine distributions; Rayleigh distribution, gamma distribution, Pareto distribution, log-logistic distribution, logistic distribution, normal distribution, Weibull distribution, lognormal distribution, and exponential distribution and the second operation, we improve K-S statistic using PHtransform. The result appears that PH-transform technique can improve the Minimum K-S estimator. The algorithms give better the Minimum K-S estimator for seven distributions; Rayleigh distribution, logistic distribution, gamma distribution, Pareto distribution, log-logistic distribution, normal distribution, Weibull distribution, log-normal distribution, and exponential distribution while the Minimum K-S estimators of normal distribution and logistic distribution are unchanged

  11. NEW EVIDENCE FOR CHARGE-SIGN-DEPENDENT MODULATION DURING THE SOLAR MINIMUM OF 2006 TO 2009

    Energy Technology Data Exchange (ETDEWEB)

    Di Felice, V. [INFN, Sezione di Roma “Tor Vergata,” I-00133 Rome (Italy); Munini, R. [INFN, Sezione di Trieste, I-34149 Trieste (Italy); Vos, E. E.; Potgieter, M. S. [Centre for Space Research, North-West University, 2520 Potchefstroom (South Africa)

    2017-01-01

    The PAMELA space experiment, in orbit since 2006, has measured cosmic rays (CRs) through the most recent period of minimum solar activity with the magnetic field polarity as A  < 0. During this entire time, galactic electrons and protons have been detected down to 70 MV and 400 MV, respectively, and their differential variation in intensity with time has been monitored with unprecedented accuracy. These observations are used to show how differently electrons and protons responded to the quiet modulation conditions that prevailed from 2006 to 2009. It is well known that particle drifts, as one of four major mechanisms for the solar modulation of CRs, cause charge-sign-dependent solar modulation. Periods of minimum solar activity provide optimal conditions in which to study these drift effects. The observed behavior is compared to the solutions of a three-dimensional model for CRs in the heliosphere, including drifts. The numerical results confirm that the difference in the evolution of electron and proton spectra during the last prolonged solar minimum is attributed to a large extent to particle drifts. We therefore present new evidence of charge-sign-dependent solar modulation, with a perspective on its peculiarities for the observed period from 2006 to 2009.

  12. The Einstein-Hilbert gravitation with minimum length

    Science.gov (United States)

    Louzada, H. L. C.

    2018-05-01

    We study the Einstein-Hilbert gravitation with the deformed Heisenberg algebra leading to the minimum length, with the intention to find and estimate the corrections in this theory, clarifying whether or not it is possible to obtain, by means of the minimum length, a theory, in D=4, which is causal, unitary and provides a massive graviton. Therefore, we will calculate and analyze the dispersion relationships of the considered theory.

  13. Improvement in operational characteristics of KEPCO’s line-commutation-type superconducting hybrid fault current limiter

    Science.gov (United States)

    Yim, S.-W.; Park, B.-C.; Jeong, Y.-T.; Kim, Y.-J.; Yang, S.-E.; Kim, W.-S.; Kim, H.-R.; Du, H.-I.

    2013-01-01

    A 22.9 kV class hybrid fault current limiter (FCL) developed by Korea Electric Power Corporation and LS Industrial Systems in 2006 operates using the line commutation mechanism and begins to limit the fault current after the first half-cycle. The first peak of the fault current is available for protective coordination in the power system. However, it also produces a large electromagnetic force and imposes a huge stress on power facilities such as the main transformer and gas-insulated switchgear. In this study, we improved the operational characteristics of the hybrid FCL in order to reduce the first peak of the fault current. While maintaining the structure of the hybrid FCL system, we developed a superconducting module that detects and limits the fault current during the first half-cycle. To maintain the protective coordination capacity, the hybrid FCL was designed to reduce the first peak value of the fault current by up to approximately 30%. The superconducting module was also designed to produce a minimum AC loss, generating a small, uniform magnetic field distribution during normal operation. Performance tests confirmed that when applied to the hybrid FCL, the superconducting module showed successful current limiting operation without any damage.

  14. Reducing tobacco use and access through strengthened minimum price laws.

    Science.gov (United States)

    McLaughlin, Ian; Pearson, Anne; Laird-Metke, Elisa; Ribisl, Kurt

    2014-10-01

    Higher prices reduce consumption and initiation of tobacco products. A minimum price law that establishes a high statutory minimum price and prohibits the industry's discounting tactics for tobacco products is a promising pricing strategy as an alternative to excise tax increases. Although some states have adopted minimum price laws on the basis of statutorily defined price "markups" over the invoice price, existing state laws have been largely ineffective at increasing the retail price. We analyzed 3 new variations of minimum price laws that hold great potential for raising tobacco prices and reducing consumption: (1) a flat rate minimum price law similar to a recent enactment in New York City, (2) an enhanced markup law, and (3) a law that incorporates both elements.

  15. A novel cell weighing method based on the minimum immobilization pressure for biological applications

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Qili [Robotics and Mechatronics Research Laboratory, Department of Mechanical and Aerospace Engineering, Monash University, Clayton 3800 (Australia); Institute of Robotics and Automatic Information System, Nankai University, Tianjin 300071 (China); Shirinzadeh, Bijan [Robotics and Mechatronics Research Laboratory, Department of Mechanical and Aerospace Engineering, Monash University, Clayton 3800 (Australia); Cui, Maosheng [Biotechnology Lab of Animal Reproduction, Tianjin Animal Sciences, Tianjin 300112 (China); Sun, Mingzhu; Liu, Yaowei; Zhao, Xin, E-mail: zhaoxin@nankai.edu.cn [Institute of Robotics and Automatic Information System, Nankai University, Tianjin 300071 (China)

    2015-07-28

    A novel weighing method for cells with spherical and other regular shapes is proposed in this paper. In this method, the relationship between the cell mass and the minimum aspiration pressure to immobilize the cell (referred to as minimum immobilization pressure) is derived for the first time according to static theory. Based on this relationship, a robotic cell weighing process is established using a traditional micro-injection system. Experimental results on porcine oocytes demonstrate that the proposed method is able to weigh cells at an average speed of 16.3 s/cell and with a success rate of more than 90%. The derived cell mass and density are in accordance with those reported in other published results. The experimental results also demonstrated that this method is able to detect less than 1% variation of the porcine oocyte mass quantitatively. It can be conducted by a pair of traditional micropipettes and a commercial pneumatic micro-injection system, and is expected to perform robotic operation on batch cells. At present, the minimum resolution of the proposed method for measuring the cell mass can be 1.25 × 10{sup −15 }kg. Above advantages make it very appropriate for quantifying the amount of the materials injected into or moved out of the cells in the biological applications, such as nuclear enucleations and embryo microinjections.

  16. A novel cell weighing method based on the minimum immobilization pressure for biological applications

    International Nuclear Information System (INIS)

    Zhao, Qili; Shirinzadeh, Bijan; Cui, Maosheng; Sun, Mingzhu; Liu, Yaowei; Zhao, Xin

    2015-01-01

    A novel weighing method for cells with spherical and other regular shapes is proposed in this paper. In this method, the relationship between the cell mass and the minimum aspiration pressure to immobilize the cell (referred to as minimum immobilization pressure) is derived for the first time according to static theory. Based on this relationship, a robotic cell weighing process is established using a traditional micro-injection system. Experimental results on porcine oocytes demonstrate that the proposed method is able to weigh cells at an average speed of 16.3 s/cell and with a success rate of more than 90%. The derived cell mass and density are in accordance with those reported in other published results. The experimental results also demonstrated that this method is able to detect less than 1% variation of the porcine oocyte mass quantitatively. It can be conducted by a pair of traditional micropipettes and a commercial pneumatic micro-injection system, and is expected to perform robotic operation on batch cells. At present, the minimum resolution of the proposed method for measuring the cell mass can be 1.25 × 10 −15  kg. Above advantages make it very appropriate for quantifying the amount of the materials injected into or moved out of the cells in the biological applications, such as nuclear enucleations and embryo microinjections

  17. Confocal laser-induced fluorescence detector for narrow capillary system with yoctomole limit of detection.

    Science.gov (United States)

    Weaver, Mitchell T; Lynch, Kyle B; Zhu, Zaifang; Chen, Huang; Lu, Joann J; Pu, Qiaosheng; Liu, Shaorong

    2017-04-01

    Laser-induced fluorescence (LIF) detectors for low-micrometer and sub-micrometer capillary on-column detection are not commercially available. In this paper, we describe in details how to construct a confocal LIF detector to address this issue. We characterize the detector by determining its limit of detection (LOD), linear dynamic range (LDR) and background signal drift; a very low LOD (~70 fluorescein molecules or 12 yoctomole fluorescein), a wide LDR (greater than 3 orders of magnitude) and a small background signal drift (~1.2-fold of the root mean square noise) are obtained. For detecting analytes inside a low-micrometer and sub-micrometer capillary, proper alignment is essential. We present a simple protocol to align the capillary with the optical system and use the position-lock capability of a translation stage to fix the capillary in position during the experiment. To demonstrate the feasibility of using this detector for narrow capillary systems, we build a 2-μm-i.d. capillary flow injection analysis (FIA) system using the newly developed LIF prototype as a detector and obtain an FIA LOD of 14 zeptomole fluorescein. We also separate a DNA ladder sample by bare narrow capillary - hydrodynamic chromatography and use the LIF prototype to monitor the resolved DNA fragments. We obtain not only well-resolved peaks but also the quantitative information of all DNA fragments. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. 12 CFR 567.2 - Minimum regulatory capital requirement.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Minimum regulatory capital requirement. 567.2... Regulatory Capital Requirements § 567.2 Minimum regulatory capital requirement. (a) To meet its regulatory capital requirement a savings association must satisfy each of the following capital standards: (1) Risk...

  19. 29 CFR 525.24 - Advisory Committee on Special Minimum Wages.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Advisory Committee on Special Minimum Wages. 525.24 Section 525.24 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... Special Minimum Wages. The Advisory Committee on Special Minimum Wages, the members of which are appointed...

  20. Transverse micro-erosion meter measurements; determining minimum sample size

    Science.gov (United States)

    Trenhaile, Alan S.; Lakhan, V. Chris

    2011-11-01

    Two transverse micro-erosion meter (TMEM) stations were installed in each of four rock slabs, a slate/shale, basalt, phyllite/schist, and sandstone. One station was sprayed each day with fresh water and the other with a synthetic sea water solution (salt water). To record changes in surface elevation (usually downwearing but with some swelling), 100 measurements (the pilot survey), the maximum for the TMEM used in this study, were made at each station in February 2010, and then at two-monthly intervals until February 2011. The data were normalized using Box-Cox transformations and analyzed to determine the minimum number of measurements needed to obtain station means that fall within a range of confidence limits of the population means, and the means of the pilot survey. The effect on the confidence limits of reducing an already small number of measurements (say 15 or less) is much greater than that of reducing a much larger number of measurements (say more than 50) by the same amount. There was a tendency for the number of measurements, for the same confidence limits, to increase with the rate of downwearing, although it was also dependent on whether the surface was treated with fresh or salt water. About 10 measurements often provided fairly reasonable estimates of rates of surface change but with fairly high percentage confidence intervals in slowly eroding rocks; however, many more measurements were generally needed to derive means within 10% of the population means. The results were tabulated and graphed to provide an indication of the approximate number of measurements required for given confidence limits, and the confidence limits that might be attained for a given number of measurements.

  1. Detection of medically important Candida species by absolute quantitation real-time polymerase chain reaction.

    Science.gov (United States)

    Than, Leslie Thian Lung; Chong, Pei Pei; Ng, Kee Peng; Seow, Heng Fong

    2015-01-01

    The number of invasive candidiasis cases has risen especially with an increase in the number of immunosuppressed and immunocom promised patients. The early detection of Candida species which is specific and sensitive is important in determining the correct administration of antifungal drugs to patients. This study aims to develop a method for the detection, identification and quantitation of medically important Candida species through quantitative polymerase chain reaction (qPCR). The isocitrate lyase (ICL) gene which is not found in mammals was chosen as the target gene of real-time PCR. Absolute quantitation of the gene copy number was achieved by constructing the plasmid containing the ICL gene which is used to generate standard curve. Twenty fungal species, two bacterial species and human DNA were tested to check the specificity of the detection method. All eight Candida species were successfully detected, identified and quantitated based on the ICL gene. A seven-log range of the gene copy number and a minimum detection limit of 10(3) copies were achieved. A one-tube absolute quantification real-time PCR that differentiates medically important Candida species via individual unique melting temperature was achieved. Analytical sensitivity and specificity were not compromised.

  2. Minimum inhibitory concentration of vancomycin to methicillin resistant Staphylococcus aureus isolated from different clinical samples at a tertiary care hospital in Nepal

    Directory of Open Access Journals (Sweden)

    Arjun Ojha Kshetry

    2016-07-01

    Full Text Available Abstract Background Methicillin resistant Staphylococcus aureus (MRSA has evolved as a serious threat to public health. It has capability to cause infections not only in health care settings but also in community. Due to the multidrug resistance shown by MRSA, there are limited treatment options for the infections caused by this superbug. Vancomycin is used as the drug of choice for the treatment of infections caused by MRSA. Different studies from all around the world have documented the emergence of strains of S. aureus those are intermediate sensitive or resistant to vancomycin. And recently, there have been reports of reduced susceptibility of MRSA to vancomycin, from Nepal also. So the main purpose of this study was to determine the minimum inhibitory concentration (MIC of vancomycin to methicillin resistant S. aureus isolated from different clinical specimens. Methods Total 125 strains of S. aureus isolated from different clinical samples at KIST Medical College and Teaching Hospital, Lalitpur, Nepal from Nov 2012 to June 2013, were subjected to MRSA detection by cefoxitin disc diffusion method. The minimum inhibitory concentrations of vancomycin to confirmed MRSA strains were determined by agar dilution method. Yellow colored colonies in mannitol salt agar, which were gram positive cocci, catalase positive and coagulase positive were confirmed to be S. aureus. Results Among, total 125 S. aureus strains isolated; 47(37.6% were MRSA. Minimum inhibitory concentrations of vancomycin to the strains of MRSA ranged from 0.125 μg/ml to 1 μg/ml. Conclusion From our findings we concluded that the rate of isolation of MRSA among all the strains of S. aureus isolated from clinical samples was very high. However, none of the MRSA strains were found to be vancomycin intermediate-sensitive or vancomycin-resistant.

  3. Limited magnetic resonance imaging of the lumbar spine has high sensitivity for detection of acute fractures, infection, and malignancy

    International Nuclear Information System (INIS)

    Wang, Benjamin; Fintelmann, Florian J.; Kamath, Ravi S.; Kattapuram, Susan V.; Rosenthal, Daniel I.

    2016-01-01

    The objective of this study is to determine how a limited protocol MR examination compares to a full conventional MR examination for the detection of non-degenerative pathology such as acute fracture, infection, and malignancy. A sample of 349 non-contrast MR exams was selected retrospectively containing a 3:1:1:1 distribution of negative/degenerative change only, acute fracture, infection, and malignancy. This resulted in an even distribution of pathology and non-pathology. A limited protocol MR exam was simulated by extracting T1-weighted sagittal and T2-weighted fat-saturated (or STIR) sagittal sequences from each exam and submitting them for blinded review by two experienced musculoskeletal radiologists. The exams were evaluated for the presence or absence of non-degenerative pathology. Interpretation of the limited exam was compared to the original report of the full examination. If either reader disagreed with the original report, the case was submitted for an unblinded adjudication process with the participation of a third musculoskeletal radiologist to establish a consensus diagnosis. There were five false negatives for a sensitivity of 96.9 % for the limited protocol MR exam. Infection in the psoas, paraspinal muscles, and sacroiliac joint, as well as acute fractures in transverse processes and sacrum were missed by one or more readers. No cases of malignancy were missed. Overall diagnostic accuracy was 96.0 % (335/349). MR imaging of the lumbar spine limited to sagittal T1-weighted and sagittal T2 fat-saturated (or STIR) sequences has high sensitivity for the detection of acute fracture, infection, or malignancy compared to a conventional MR examination. (orig.)

  4. Limited magnetic resonance imaging of the lumbar spine has high sensitivity for detection of acute fractures, infection, and malignancy

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Benjamin; Fintelmann, Florian J.; Kamath, Ravi S.; Kattapuram, Susan V.; Rosenthal, Daniel I. [Massachusetts General Hospital, Department of Radiology, Boston, MA (United States)

    2016-12-15

    The objective of this study is to determine how a limited protocol MR examination compares to a full conventional MR examination for the detection of non-degenerative pathology such as acute fracture, infection, and malignancy. A sample of 349 non-contrast MR exams was selected retrospectively containing a 3:1:1:1 distribution of negative/degenerative change only, acute fracture, infection, and malignancy. This resulted in an even distribution of pathology and non-pathology. A limited protocol MR exam was simulated by extracting T1-weighted sagittal and T2-weighted fat-saturated (or STIR) sagittal sequences from each exam and submitting them for blinded review by two experienced musculoskeletal radiologists. The exams were evaluated for the presence or absence of non-degenerative pathology. Interpretation of the limited exam was compared to the original report of the full examination. If either reader disagreed with the original report, the case was submitted for an unblinded adjudication process with the participation of a third musculoskeletal radiologist to establish a consensus diagnosis. There were five false negatives for a sensitivity of 96.9 % for the limited protocol MR exam. Infection in the psoas, paraspinal muscles, and sacroiliac joint, as well as acute fractures in transverse processes and sacrum were missed by one or more readers. No cases of malignancy were missed. Overall diagnostic accuracy was 96.0 % (335/349). MR imaging of the lumbar spine limited to sagittal T1-weighted and sagittal T2 fat-saturated (or STIR) sequences has high sensitivity for the detection of acute fracture, infection, or malignancy compared to a conventional MR examination. (orig.)

  5. Statistical physics when the minimum temperature is not absolute zero

    Science.gov (United States)

    Chung, Won Sang; Hassanabadi, Hassan

    2018-04-01

    In this paper, the nonzero minimum temperature is considered based on the third law of thermodynamics and existence of the minimal momentum. From the assumption of nonzero positive minimum temperature in nature, we deform the definitions of some thermodynamical quantities and investigate nonzero minimum temperature correction to the well-known thermodynamical problems.

  6. 42 CFR 422.382 - Minimum net worth amount.

    Science.gov (United States)

    2010-10-01

    ... that CMS considers appropriate to reduce, control or eliminate start-up administrative costs. (b) After... section. (c) Calculation of the minimum net worth amount—(1) Cash requirement. (i) At the time of application, the organization must maintain at least $750,000 of the minimum net worth amount in cash or cash...

  7. Minimum Competencies in Undergraduate Motor Development. Guidance Document

    Science.gov (United States)

    National Association for Sport and Physical Education, 2004

    2004-01-01

    The minimum competency guidelines in Motor Development described herein at the undergraduate level may be gained in one or more motor development course(s) or through other courses provided in an undergraduate curriculum. The minimum guidelines include: (1) Formulation of a developmental perspective; (2) Knowledge of changes in motor behavior…

  8. Modelling nitrite dynamics and associated feedback processes in the Benguela oxygen minimum zone

    Science.gov (United States)

    Mashifane, T. B.; Vichi, M.; Waldron, H. N.; Machu, E.; Garçonc, V.

    2016-08-01

    Understanding nitrite dynamics in oxygen minimum zones (OMZs) is a challenge as it represents an intermediary nitrogen species with a short turnover time. Nitrite is also reduced to nitrogen in OMZs, preventing its accumulation. This creates difficulties in detecting nitrite with colorimetric methods as concentrations may occur below detection limits in some regions. Nitrite concentrations are key to understanding intermediate nitrogen processes and their implication for nitrogen loss in OMZs. A coupled physical-biogeochemical model is applied in the Benguela OMZ to study nitrite dynamics and its associated feedback processes. Simulated results show occurrence of primary and secondary nitrite maxima in the Benguela shelf waters. The primary nitrite maxima in the Benguela are attributed to nitrification and nitrate assimilation as they occur in association with the nitracline. Secondary nitrite maxima accumulate in the Angola-Benguela Front (ABF) OMZ and are attributed to denitrification. The secondary nitrite maxima are consumed by anaerobic ammonium oxidation (anammox) off Walvis Bay. Nitrite maxima are restricted to the shelf off Walvis Bay and advected offshore in the ABF region. Interchanges between the poleward South Atlantic Central Water (SACW) and the equatorward, well-aerated Eastern South Atlantic Central Water (ESACW) drive the seasonality of nitrogen processes in the Benguela. Subsequent nitrite reduction in the Benguela OMZ leads to nitrous oxide production, with high concentrations occurring in the ABF region as a result of nitrification and denitrification. Off Walvis Bay, nitrous oxide production is low since nitrite is consumed by anammox. Nitrous oxide production occurs in thermocline, intermediate and deeper water masses in the ABF region. High N fluxes in the Benguela are attributed to nitrification as compared to anammox and denitrification. Results from this study demonstrate the role of intermediate nitrogen species in nitrogen feedback

  9. Minimum Wages and Skill Acquisition: Another Look at Schooling Effects.

    Science.gov (United States)

    Neumark, David; Wascher, William

    2003-01-01

    Examines the effects of minimum wage on schooling, seeking to reconcile some of the contradictory results in recent research using Current Population Survey data from the late 1970s through the 1980s. Findings point to negative effects of minimum wages on school enrollment, bolstering the findings of negative effects of minimum wages on enrollment…

  10. Minimum indoor temperature threshold recommendations for English homes in winter - A systematic review.

    Science.gov (United States)

    Jevons, R; Carmichael, C; Crossley, A; Bone, A

    2016-07-01

    To identify and assess the available evidence on the impacts of cold indoor temperature thresholds on human health and make evidence-based recommendations for English homes. Systematic literature review. A systematic search of peer-reviewed published literature from the UK and countries with similar climates, and grading of the evidence using the National Institute of Health (NIH) framework was followed by a discussion with experts and formulation of recommendations. Twenty papers were included. Studies were included if they were conducted outside England but were from countries considered to have similar climates. Studies included two small randomised controlled trials, two cohort studies and one case control study; other studies were cross-sectional, largely laboratory-based studies. Health effects in the general population start to occur at around 18 °C. Effects in older people are more profound than in younger adults. Older people are less able to perceive low temperatures. Although evidence was limited, a strong argument for setting thresholds remains. The effects observed on the general population and the effects on those more vulnerable makes a case for a recommended minimum temperature for all. Health messages should be clear and simple, allowing informed choices to be made. A threshold of 18 °C was considered the evidence based and practical minimum temperature at which a home should be kept during winter in England. There is limited evidence available on minimum temperature thresholds for homes. However a recommendation of at least 18 °C for the whole population with nuancing of messages for those more vulnerable to the effects of cold can be made from the results of the retrieved studies. Heating homes to at least 18 °C (65 °F) in winter poses minimal risk to the health of a sedentary person, wearing suitable clothing. Copyright © 2016 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  11. 14 CFR 91.155 - Basic VFR weather minimums.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Basic VFR weather minimums. 91.155 Section...) AIR TRAFFIC AND GENERAL OPERATING RULES GENERAL OPERATING AND FLIGHT RULES Flight Rules Visual Flight Rules § 91.155 Basic VFR weather minimums. (a) Except as provided in paragraph (b) of this section and...

  12. Potential and limits of Raman spectroscopy for carotenoid detection in microorganisms: implications for astrobiology

    Science.gov (United States)

    Jehlička, Jan; Edwards, Howell G. M.; Osterrothová, Kateřina; Novotná, Julie; Nedbalová, Linda; Kopecký, Jiří; Němec, Ivan; Oren, Aharon

    2014-01-01

    In this paper, it is demonstrated how Raman spectroscopy can be used to detect different carotenoids as possible biomarkers in various groups of microorganisms. The question which arose from previous studies concerns the level of unambiguity of discriminating carotenoids using common Raman microspectrometers. A series of laboratory-grown microorganisms of different taxonomic affiliation was investigated, such as halophilic heterotrophic bacteria, cyanobacteria, the anoxygenic phototrophs, the non-halophilic heterotrophs as well as eukaryotes (Ochrophyta, Rhodophyta and Chlorophyta). The data presented show that Raman spectroscopy is a suitable tool to assess the presence of carotenoids of these organisms in cultures. Comparison is made with the high-performance liquid chromatography approach of analysing pigments in extracts. Direct measurements on cultures provide fast and reliable identification of the pigments. Some of the carotenoids studied are proposed as tracers for halophiles, in contrast with others which can be considered as biomarkers of other genera. The limits of application of Raman spectroscopy are discussed for a few cases where the current Raman spectroscopic approach does not allow discriminating structurally very similar carotenoids. The database reported can be used for applications in geobiology and exobiology for the detection of pigment signals in natural settings. PMID:25368348

  13. Evaluating Small Sphere Limit of the Wang-Yau Quasi-Local Energy

    Science.gov (United States)

    Chen, Po-Ning; Wang, Mu-Tao; Yau, Shing-Tung

    2018-01-01

    In this article, we study the small sphere limit of the Wang-Yau quasi-local energy defined in Wang and Yau (Phys Rev Lett 102(2):021101, 2009, Commun Math Phys 288(3):919-942, 2009). Given a point p in a spacetime N, we consider a canonical family of surfaces approaching p along its future null cone and evaluate the limit of the Wang-Yau quasi-local energy. The evaluation relies on solving an "optimal embedding equation" whose solutions represent critical points of the quasi-local energy. For a spacetime with matter fields, the scenario is similar to that of the large sphere limit found in Chen et al. (Commun Math Phys 308(3):845-863, 2011). Namely, there is a natural solution which is a local minimum, and the limit of its quasi-local energy recovers the stress-energy tensor at p. For a vacuum spacetime, the quasi-local energy vanishes to higher order and the solution of the optimal embedding equation is more complicated. Nevertheless, we are able to show that there exists a solution that is a local minimum and that the limit of its quasi-local energy is related to the Bel-Robinson tensor. Together with earlier work (Chen et al. 2011), this completes the consistency verification of the Wang-Yau quasi-local energy with all classical limits.

  14. Minimum Wages and Teen Employment: A Spatial Panel Approach

    OpenAIRE

    Charlene Kalenkoski; Donald Lacombe

    2011-01-01

    The authors employ spatial econometrics techniques and Annual Averages data from the U.S. Bureau of Labor Statistics for 1990-2004 to examine how changes in the minimum wage affect teen employment. Spatial econometrics techniques account for the fact that employment is correlated across states. Such correlation may exist if a change in the minimum wage in a state affects employment not only in its own state but also in other, neighboring states. The authors show that state minimum wages negat...

  15. Composite Estimation for Single-Index Models with Responses Subject to Detection Limits

    KAUST Repository

    Tang, Yanlin; Wang, Huixia Judy; Liang, Hua

    2017-01-01

    We propose a semiparametric estimator for single-index models with censored responses due to detection limits. In the presence of left censoring, the mean function cannot be identified without any parametric distributional assumptions, but the quantile function is still identifiable at upper quantile levels. To avoid parametric distributional assumption, we propose to fit censored quantile regression and combine information across quantile levels to estimate the unknown smooth link function and the index parameter. Under some regularity conditions, we show that the estimated link function achieves the non-parametric optimal convergence rate, and the estimated index parameter is asymptotically normal. The simulation study shows that the proposed estimator is competitive with the omniscient least squares estimator based on the latent uncensored responses for data with normal errors but much more efficient for heavy-tailed data under light and moderate censoring. The practical value of the proposed method is demonstrated through the analysis of a human immunodeficiency virus antibody data set.

  16. Composite Estimation for Single-Index Models with Responses Subject to Detection Limits

    KAUST Repository

    Tang, Yanlin

    2017-11-03

    We propose a semiparametric estimator for single-index models with censored responses due to detection limits. In the presence of left censoring, the mean function cannot be identified without any parametric distributional assumptions, but the quantile function is still identifiable at upper quantile levels. To avoid parametric distributional assumption, we propose to fit censored quantile regression and combine information across quantile levels to estimate the unknown smooth link function and the index parameter. Under some regularity conditions, we show that the estimated link function achieves the non-parametric optimal convergence rate, and the estimated index parameter is asymptotically normal. The simulation study shows that the proposed estimator is competitive with the omniscient least squares estimator based on the latent uncensored responses for data with normal errors but much more efficient for heavy-tailed data under light and moderate censoring. The practical value of the proposed method is demonstrated through the analysis of a human immunodeficiency virus antibody data set.

  17. Nowcasting daily minimum air and grass temperature

    Science.gov (United States)

    Savage, M. J.

    2016-02-01

    Site-specific and accurate prediction of daily minimum air and grass temperatures, made available online several hours before their occurrence, would be of significant benefit to several economic sectors and for planning human activities. Site-specific and reasonably accurate nowcasts of daily minimum temperature several hours before its occurrence, using measured sub-hourly temperatures hours earlier in the morning as model inputs, was investigated. Various temperature models were tested for their ability to accurately nowcast daily minimum temperatures 2 or 4 h before sunrise. Temperature datasets used for the model nowcasts included sub-hourly grass and grass-surface (infrared) temperatures from one location in South Africa and air temperature from four subtropical sites varying in altitude (USA and South Africa) and from one site in central sub-Saharan Africa. Nowcast models used employed either exponential or square root functions to describe the rate of nighttime temperature decrease but inverted so as to determine the minimum temperature. The models were also applied in near real-time using an open web-based system to display the nowcasts. Extrapolation algorithms for the site-specific nowcasts were also implemented in a datalogger in an innovative and mathematically consistent manner. Comparison of model 1 (exponential) nowcasts vs measured daily minima air temperatures yielded root mean square errors (RMSEs) <1 °C for the 2-h ahead nowcasts. Model 2 (also exponential), for which a constant model coefficient ( b = 2.2) was used, was usually slightly less accurate but still with RMSEs <1 °C. Use of model 3 (square root) yielded increased RMSEs for the 2-h ahead comparisons between nowcasted and measured daily minima air temperature, increasing to 1.4 °C for some sites. For all sites for all models, the comparisons for the 4-h ahead air temperature nowcasts generally yielded increased RMSEs, <2.1 °C. Comparisons for all model nowcasts of the daily grass

  18. Detection limits for radioanalytical counting techniques

    International Nuclear Information System (INIS)

    Hartwell, J.K.

    1975-06-01

    In low-level radioanalysis it is usually necessary to test the sample net counts against some ''Critical Level'' in order to determine if a given result indicates detection. This is an interpretive review of the work by Nicholson (1963), Currie (1968) and Gilbert (1974). Nicholson's evaluation of three different computational formulas for estimation of the ''Critical Level'' is discussed. The details of Nicholson's evaluation are presented along with a basic discussion of the testing procedures used. Recommendations are presented for calculation of confidence intervals, for reporting of analytical results, and for extension of the derived formula to more complex cases such as multiple background counts, multiple use of a single background count, and gamma spectrometric analysis

  19. Assessment of detection limits of fiber-optic distributed temperature sensing for detection of illicit connections

    NARCIS (Netherlands)

    Nienhuis, J.; De Haan, C.; Langeveld, J.G.; Klootwijk, M.; Clemens, F.H.L.R.

    2012-01-01

    Distributed Temperature Sensing (DTS) with fiber-optic cables is a powerful tool to detect illicit connections in storm sewer systems. High frequency temperature measurements along the in-sewer cable create a detailed representation of temperature anomalies due to illicit discharges. The detection

  20. A note on minimum-variance theory and beyond

    Energy Technology Data Exchange (ETDEWEB)

    Feng Jianfeng [Department of Informatics, Sussex University, Brighton, BN1 9QH (United Kingdom); Tartaglia, Giangaetano [Physics Department, Rome University ' La Sapienza' , Rome 00185 (Italy); Tirozzi, Brunello [Physics Department, Rome University ' La Sapienza' , Rome 00185 (Italy)

    2004-04-30

    We revisit the minimum-variance theory proposed by Harris and Wolpert (1998 Nature 394 780-4), discuss the implications of the theory on modelling the firing patterns of single neurons and analytically find the optimal control signals, trajectories and velocities. Under the rate coding assumption, input control signals employed in the minimum-variance theory should be Fitts processes rather than Poisson processes. Only if information is coded by interspike intervals, Poisson processes are in agreement with the inputs employed in the minimum-variance theory. For the integrate-and-fire model with Fitts process inputs, interspike intervals of efferent spike trains are very irregular. We introduce diffusion approximations to approximate neural models with renewal process inputs and present theoretical results on calculating moments of interspike intervals of the integrate-and-fire model. Results in Feng, et al (2002 J. Phys. A: Math. Gen. 35 7287-304) are generalized. In conclusion, we present a complete picture on the minimum-variance theory ranging from input control signals, to model outputs, and to its implications on modelling firing patterns of single neurons.

  1. A note on minimum-variance theory and beyond

    International Nuclear Information System (INIS)

    Feng Jianfeng; Tartaglia, Giangaetano; Tirozzi, Brunello

    2004-01-01

    We revisit the minimum-variance theory proposed by Harris and Wolpert (1998 Nature 394 780-4), discuss the implications of the theory on modelling the firing patterns of single neurons and analytically find the optimal control signals, trajectories and velocities. Under the rate coding assumption, input control signals employed in the minimum-variance theory should be Fitts processes rather than Poisson processes. Only if information is coded by interspike intervals, Poisson processes are in agreement with the inputs employed in the minimum-variance theory. For the integrate-and-fire model with Fitts process inputs, interspike intervals of efferent spike trains are very irregular. We introduce diffusion approximations to approximate neural models with renewal process inputs and present theoretical results on calculating moments of interspike intervals of the integrate-and-fire model. Results in Feng, et al (2002 J. Phys. A: Math. Gen. 35 7287-304) are generalized. In conclusion, we present a complete picture on the minimum-variance theory ranging from input control signals, to model outputs, and to its implications on modelling firing patterns of single neurons

  2. Systematic optimization of multiplex zymography protocol to detect active cathepsins K, L, S, and V in healthy and diseased tissue: compromise among limits of detection, reduced time, and resources.

    Science.gov (United States)

    Dumas, Jerald E; Platt, Manu O

    2013-07-01

    Cysteine cathepsins are a family of proteases identified in cancer, atherosclerosis, osteoporosis, arthritis, and a number of other diseases. As this number continues to rise, so does the need for low cost, broad use quantitative assays to detect their activity and can be translated to the clinic in the hospital or in low resource settings. Multiplex cathepsin zymography is one such assay that detects subnanomolar levels of active cathepsins K, L, S, and V in cell or tissue preparations observed as clear bands of proteolytic activity after gelatin substrate SDS-PAGE with conditions optimal for cathepsin renaturing and activity. Densitometric analysis of the zymogram provides quantitative information from this low cost assay. After systematic modifications to optimize cathepsin zymography, we describe reduced electrophoresis time from 2 h to 10 min, incubation assay time from overnight to 4 h, and reduced minimal tissue protein necessary while maintaining sensitive detection limits; an evaluation of the pros and cons of each modification is also included. We further describe image acquisition by Smartphone camera, export to Matlab, and densitometric analysis code to quantify and report cathepsin activity, adding portability and replacing large scale, darkbox imaging equipment that could be cost prohibitive in limited resource settings.

  3. Systematic optimization of multiplex zymography protocol to detect active cathepsins K, L, S, and V in healthy and diseased tissue: compromise between limits of detection, reduced time, and resources

    Science.gov (United States)

    Dumas, Jerald E.; Platt, Manu O.

    2013-01-01

    Cysteine cathepsins are a family of proteases identified in cancer, atherosclerosis, osteoporosis, arthritis and a number of other diseases. As this number continues to rise, so does the need for low cost, broad use quantitative assays to detect their activity and can be translated to the clinic in the hospital or in low resource settings. Multiplex cathepsin zymography is one such assay that detects subnanomolar levels of active cathepsins K, L, S, and V in cell or tissue preparations observed as cleared bands of proteolytic activity after gelatin substrate SDS-PAGE with conditions optimal for cathepsin renaturing and activity. Densitometric analysis of the zymogram provides quantitative information from this low cost assay. After systematic modifications to optimize cathepsin zymography, we describe reduced electrophoresis time from 2 hours to 10 minutes, incubation assay time from overnight to 4 hours, and reduced minimal tissue protein necessary while maintaining sensitive detection limits; an evaluation of the pros and cons of each modification is also included. We further describe image acquisition by smartphone camera, export to Matlab, and densitometric analysis code to quantify and report cathepsin activity, adding portability and replacing large scale, darkbox imaging equipment that could be cost prohibitive in limited resource settings. PMID:23532386

  4. Split-plot fractional designs: Is minimum aberration enough?

    DEFF Research Database (Denmark)

    Kulahci, Murat; Ramirez, Jose; Tobias, Randy

    2006-01-01

    Split-plot experiments are commonly used in industry for product and process improvement. Recent articles on designing split-plot experiments concentrate on minimum aberration as the design criterion. Minimum aberration has been criticized as a design criterion for completely randomized fractional...... factorial design and alternative criteria, such as the maximum number of clear two-factor interactions, are suggested (Wu and Hamada (2000)). The need for alternatives to minimum aberration is even more acute for split-plot designs. In a standard split-plot design, there are several types of two...... for completely randomized designs. Consequently, we provide a modified version of the maximum number of clear two-factor interactions design criterion to be used for split-plot designs....

  5. Support vector machine as a binary classifier for automated object detection in remotely sensed data

    International Nuclear Information System (INIS)

    Wardaya, P D

    2014-01-01

    In the present paper, author proposes the application of Support Vector Machine (SVM) for the analysis of satellite imagery. One of the advantages of SVM is that, with limited training data, it may generate comparable or even better results than the other methods. The SVM algorithm is used for automated object detection and characterization. Specifically, the SVM is applied in its basic nature as a binary classifier where it classifies two classes namely, object and background. The algorithm aims at effectively detecting an object from its background with the minimum training data. The synthetic image containing noises is used for algorithm testing. Furthermore, it is implemented to perform remote sensing image analysis such as identification of Island vegetation, water body, and oil spill from the satellite imagery. It is indicated that SVM provides the fast and accurate analysis with the acceptable result

  6. Support vector machine as a binary classifier for automated object detection in remotely sensed data

    Science.gov (United States)

    Wardaya, P. D.

    2014-02-01

    In the present paper, author proposes the application of Support Vector Machine (SVM) for the analysis of satellite imagery. One of the advantages of SVM is that, with limited training data, it may generate comparable or even better results than the other methods. The SVM algorithm is used for automated object detection and characterization. Specifically, the SVM is applied in its basic nature as a binary classifier where it classifies two classes namely, object and background. The algorithm aims at effectively detecting an object from its background with the minimum training data. The synthetic image containing noises is used for algorithm testing. Furthermore, it is implemented to perform remote sensing image analysis such as identification of Island vegetation, water body, and oil spill from the satellite imagery. It is indicated that SVM provides the fast and accurate analysis with the acceptable result.

  7. Acousto-Optic Q-Switched Fiber Laser-Based Intra-Cavity Photoacoustic Spectroscopy for Trace Gas Detection.

    Science.gov (United States)

    Zhang, Qinduan; Chang, Jun; Wang, Qiang; Wang, Zongliang; Wang, Fupeng; Qin, Zengguang

    2017-12-25

    We proposed a new method for gas detection in photoacoustic spectroscopy based on acousto-optic Q-switched fiber laser by merging a transmission PAS cell (resonant frequency f ₀ = 5.3 kHz) inside the fiber laser cavity. The Q-switching was achieved by an acousto-optic modulator, achieving a peak pulse power of ~679 mW in the case of the acousto-optic modulation signal with an optimized duty ratio of 10%. We used a custom-made fiber Bragg grating with a central wavelength of 1530.37 nm (the absorption peak of C₂H₂) to select the laser wavelength. The system achieved a linear response (R² = 0.9941) in a concentration range from 400 to 7000 ppmv, and the minimum detection limit compared to that of a conventional intensity modulation system was enhanced by 94.2 times.

  8. DNA isolation protocols affect the detection limit of PCR approaches of bacteria in samples from the human gastrointestinal tract

    NARCIS (Netherlands)

    Zoetendal, E.G.; Ben-Amor, K.; Akkermans, A.D.L.; Abee, T.; Vos, de W.M.

    2001-01-01

    A major concern in molecular ecological studies is the lysis efficiency of different bacteria in a complex ecosystem. We used a PCR-based 16S rDNA approach to determine the effect of two DNA isolation protocols (i.e. the bead beating and Triton-X100 method) on the detection limit of seven

  9. Applicability of the minimum entropy generation method for optimizing thermodynamic cycles

    Institute of Scientific and Technical Information of China (English)

    Cheng Xue-Tao; Liang Xin-Gang

    2013-01-01

    Entropy generation is often used as a figure of merit in thermodynamic cycle optimizations.In this paper,it is shown that the applicability of the minimum entropy generation method to optimizing output power is conditional.The minimum entropy generation rate and the minimum entropy generation number do not correspond to the maximum output power when the total heat into the system of interest is not prescribed.For the cycles whose working medium is heated or cooled by streams with prescribed inlet temperatures and prescribed heat capacity flow rates,it is theoretically proved that both the minimum entropy generation rate and the minimum entropy generation number correspond to the maximum output power when the virtual entropy generation induced by dumping the used streams into the environment is considered.However,the minimum principle of entropy generation is not tenable in the case that the virtual entropy generation is not included,because the total heat into the system of interest is not fixed.An irreversible Carnot cycle and an irreversible Brayton cycle are analysed.The minimum entropy generation rate and the minimum entropy generation number do not correspond to the maximum output power if the heat into the system of interest is not prescribed.

  10. Applicability of the minimum entropy generation method for optimizing thermodynamic cycles

    International Nuclear Information System (INIS)

    Cheng Xue-Tao; Liang Xin-Gang

    2013-01-01

    Entropy generation is often used as a figure of merit in thermodynamic cycle optimizations. In this paper, it is shown that the applicability of the minimum entropy generation method to optimizing output power is conditional. The minimum entropy generation rate and the minimum entropy generation number do not correspond to the maximum output power when the total heat into the system of interest is not prescribed. For the cycles whose working medium is heated or cooled by streams with prescribed inlet temperatures and prescribed heat capacity flow rates, it is theoretically proved that both the minimum entropy generation rate and the minimum entropy generation number correspond to the maximum output power when the virtual entropy generation induced by dumping the used streams into the environment is considered. However, the minimum principle of entropy generation is not tenable in the case that the virtual entropy generation is not included, because the total heat into the system of interest is not fixed. An irreversible Carnot cycle and an irreversible Brayton cycle are analysed. The minimum entropy generation rate and the minimum entropy generation number do not correspond to the maximum output power if the heat into the system of interest is not prescribed. (general)

  11. Minimum Moduli in Von Neumann Algebras | Gopalraj | Quaestiones ...

    African Journals Online (AJOL)

    In this paper we answer a question raised in [12] in the affirmative, namely that the essential minimum modulus of an element in a von. Neumann algebra, relative to any norm closed two-sided ideal, is equal to the minimum modulus of the element perturbed by an element from the ideal. As a corollary of this result, we ...

  12. Subjective well-being and minimum wages: Evidence from U.S. states.

    Science.gov (United States)

    Kuroki, Masanori

    2018-02-01

    This paper investigates whether increases in minimum wages are associated with higher life satisfaction by using monthly-level state minimum wages and individual-level data from the 2005-2010 Behavioral Risk Factor Surveillance System. The magnitude I find suggests that a 10% increase in the minimum wage is associated with a 0.03-point increase in life satisfaction for workers without a high school diploma, on a 4-point scale. Contrary to popular belief that higher minimum wages hurt business owners, I find little evidence that higher minimum wages lead to the loss of well-being among self-employed people. Copyright © 2017 John Wiley & Sons, Ltd.

  13. Minimum training requirement in ultrasound imaging of peripheral arterial disease.

    Science.gov (United States)

    Eiberg, J P; Hansen, M A; Grønvall Rasmussen, J B; Schroeder, T V

    2008-09-01

    To demonstrate the minimum training requirement when performing ultrasound of peripheral arterial disease. Prospective and blinded comparative study. 100 limbs in 100 consecutive patients suffering from peripheral arterial disease, 74% suffering critical limb ischemia, were enrolled during a 9 months period. One physician with limited ultrasound experience performed all the ultrasound examinations of the arteries of the most symptomatic limb. Before enrolling any patients 15 duplex ultrasound examinations were performed supervised by an experienced vascular technologist. All patients had a digital subtraction arteriography performed by an experienced vascular radiologist, unaware of the ultrasound result. The number of insufficiently insonated segments (non-diagnostic segments) was significantly reduced during the study; from 9% among the initial 50 limbs to 2% among the last 50 limbs (Pultrasound and arteriography from the initial 50 patients (overall Kappa=0.66, (95%-CI: 0.60-0.72); supragenicular Kappa=0.73 (95%-CI: 0.64-0.82); infragenicular Kappa=0.61 (95%-CI: 0.54-0.69)) to the last 50 patients (overall Kappa=0.66 (95%-CI: 0.60-0.72), supragenicular Kappa=0.67 (95%-CI: 0.57-0.76); infragenicular Kappa=0.66 (95%-CI: 0.58-0.73)). The minimum training requirement in ultrasound imaging of peripheral arterial disease appears to be less than 50 ultrasound examinations (probably only 15 examinations) for the supragenicular segments and 100 examinations for the infragenicular segments.

  14. Six months into Myanmar's minimum wage: Reflecting on progress ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-04-25

    Apr 25, 2016 ... Participants examined recent results from an IDRC-funded enterprise survey, ... of a minimum wage, and how they have coped with the new situation.” ... Debate on the impact of minimum wages on employment continues ...

  15. Do minimum wages reduce poverty? Evidence from Central America ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-12-16

    Dec 16, 2010 ... Raising minimum wages has traditionally been considered a way to protect poor ... However, the effect of raising minimum wages remains an empirical question ... ​More than 70 of Vietnamese entrepreneurs choose to start a ...

  16. Experimental performance assessment of the sub-band minimum variance beamformer for ultrasound imaging

    DEFF Research Database (Denmark)

    Diamantis, Konstantinos; Greenaway, Alan H.; Anderson, Tom

    2017-01-01

    Recent progress in adaptive beamforming techniques for medical ultrasound has shown that current resolution limits can be surpassed. One method of obtaining improved lateral resolution is the Minimum Variance (MV) beamformer. The frequency domain implementation of this method effectively divides...... the broadband ultrasound signals into sub-bands (MVS) to conform with the narrow-band assumption of the original MV theory. This approach is investigated here using experimental Synthetic Aperture (SA) data from wire and cyst phantoms. A 7 MHz linear array transducer is used with the SARUS experimental...

  17. Sensitive helium leak detection in a deuterium atmosphere using a high-resolution quadrupole mass spectrometer

    International Nuclear Information System (INIS)

    Hiroki, S.; Abe, T.; Murakami, Y.

    1996-01-01

    In fusion machines, realizing a high-purity plasma is a key to improving the plasma parameters. Thus, leak detection is a necessary part of reducing the leak rate to a tolerable level. However, a conventional helium ( 4 He) leak detector is useless in fusion machines with a deuterium (D 2 ) plasma, because retained D particles on the first walls release D 2 for a long period and the released D 2 interferes with the signals from the leaked 4 He due to the near identical masses of 4.0026 u ( 4 He) and 4.0282 u (D 2 ). A high-resolution quadrupole mass spectrometer (HR-QMS) that we have recently developed, can detect a 4 He + population as small as 10 -4 peak in a D 2 atmosphere. Thus, the HR-QMS has been applied to detect 4 He leaks. To improve the minimum detectable limit of 4 He leak, a differentially pumped HR-QMS analyzer was attached to a chamber of the 4 He leak detector. In conclusion, the improved 4 He leak detector could detect 4 He leaks of the order of 10 -10 Pa · m 3 /s in a D 2 atmosphere. (Author)

  18. Nonlinear dimension reduction and clustering by Minimum Curvilinearity unfold neuropathic pain and tissue embryological classes.

    Science.gov (United States)

    Cannistraci, Carlo Vittorio; Ravasi, Timothy; Montevecchi, Franco Maria; Ideker, Trey; Alessio, Massimo

    2010-09-15

    Nonlinear small datasets, which are characterized by low numbers of samples and very high numbers of measures, occur frequently in computational biology, and pose problems in their investigation. Unsupervised hybrid-two-phase (H2P) procedures-specifically dimension reduction (DR), coupled with clustering-provide valuable assistance, not only for unsupervised data classification, but also for visualization of the patterns hidden in high-dimensional feature space. 'Minimum Curvilinearity' (MC) is a principle that-for small datasets-suggests the approximation of curvilinear sample distances in the feature space by pair-wise distances over their minimum spanning tree (MST), and thus avoids the introduction of any tuning parameter. MC is used to design two novel forms of nonlinear machine learning (NML): Minimum Curvilinear embedding (MCE) for DR, and Minimum Curvilinear affinity propagation (MCAP) for clustering. Compared with several other unsupervised and supervised algorithms, MCE and MCAP, whether individually or combined in H2P, overcome the limits of classical approaches. High performance was attained in the visualization and classification of: (i) pain patients (proteomic measurements) in peripheral neuropathy; (ii) human organ tissues (genomic transcription factor measurements) on the basis of their embryological origin. MC provides a valuable framework to estimate nonlinear distances in small datasets. Its extension to large datasets is prefigured for novel NMLs. Classification of neuropathic pain by proteomic profiles offers new insights for future molecular and systems biology characterization of pain. Improvements in tissue embryological classification refine results obtained in an earlier study, and suggest a possible reinterpretation of skin attribution as mesodermal. https://sites.google.com/site/carlovittoriocannistraci/home.

  19. Few molecule SERS detection using nanolens based plasmonic nanostructure: application to point mutation detection

    KAUST Repository

    Das, Gobind

    2016-10-27

    Advancements in nanotechnology fabrication techniques allow the possibility to design and fabricate a device with a minimum gap (<10 nm) between the composing nanostructures in order to obtain better control over the creation and spatial definition of plasmonic hot-spots. The present study is intended to show the fabrication of nanolens and their application to single/few molecules detection. Theoretical simulations were performed on different designs of real structures, including comparison of rough and smooth surfaces. Various molecules (rhodamine 6G, benzenethiol and BRCA1/BRCT peptides) were examined in this regard. Single molecule detection was possible for synthetic peptides, with a possible application in early detection of diseases. © The Royal Society of Chemistry.

  20. Few molecule SERS detection using nanolens based plasmonic nanostructure: application to point mutation detection

    KAUST Repository

    Das, Gobind; Alrasheed, Salma; Coluccio, Maria Laura; Gentile, Francesco; Nicastri, Annalisa; Candeloro, Patrizio; Cuda, Giovanni; Perozziello, Gerardo; Di Fabrizio, Enzo M.

    2016-01-01

    Advancements in nanotechnology fabrication techniques allow the possibility to design and fabricate a device with a minimum gap (<10 nm) between the composing nanostructures in order to obtain better control over the creation and spatial definition of plasmonic hot-spots. The present study is intended to show the fabrication of nanolens and their application to single/few molecules detection. Theoretical simulations were performed on different designs of real structures, including comparison of rough and smooth surfaces. Various molecules (rhodamine 6G, benzenethiol and BRCA1/BRCT peptides) were examined in this regard. Single molecule detection was possible for synthetic peptides, with a possible application in early detection of diseases. © The Royal Society of Chemistry.