WorldWideScience

Sample records for mexico initiative targets

  1. New Mexico Clean Energy Initiatives

    Science.gov (United States)

    This presentation addresses New Mexico oil and gas development, brownfields, mining development, renewable energy development, renewable resources, renewable standards, solar opportunities, climate change, and energy efficiency.

  2. NASA Gulf of Mexico Initiative Hypoxia Research

    Science.gov (United States)

    Armstrong, Curtis D.

    2012-01-01

    The Applied Science & Technology Project Office at Stennis Space Center (SSC) manages NASA's Gulf of Mexico Initiative (GOMI). Addressing short-term crises and long-term issues, GOMI participants seek to understand the environment using remote sensing, in-situ observations, laboratory analyses, field observations and computational models. New capabilities are transferred to end-users to help them make informed decisions. Some GOMI activities of interest to the hypoxia research community are highlighted.

  3. Inflation targeting and economic performance: The case of Mexico

    Directory of Open Access Journals (Sweden)

    Carrasco Carlos A.

    2011-01-01

    Full Text Available In the paper we analyze the impact of Inflation Targeting (IT in Mexico. The objective is to evaluate the impact of the implementation of inflation targeting and full-fledged inflation targeting (FFIT on the level and the variability of the inflation and the output in the Mexican economy. We conclude that inflation rates had been reduced in Mexico before the introduction of IT and FFIT. In our opinion, the structural reforms, including the Banxico reforms, are the main determinants of the decrease in inflation and its variability. The main impact of IT would have been the lock-in of inflation expectations around a low rate of inflation.

  4. The Gulf of Mexico research initiative: It takes a village

    Science.gov (United States)

    Colwell, Rita R.

    2016-07-01

    The Gulf of Mexico Research Initiative (GoMRI) was established at the time of one of the most significant ecological events in recent memory, the Deepwater Horizon oil spill. Defined by the discharge of over 150 million gallons of crude oil and the introduction of over 1.8 million gallons of chemical dispersants into the Gulf system, the impacts of the Deepwater Horizon disaster reached the Gulf Coast's wetlands and beaches and impacted the surface and deep ocean. The ecological story of the event reveals a strong linkage between the deep sea research community and research priorities in the Gulf of Mexico (coastal processes, human health, etc.). Deep Sea research efforts have revealed critical parts of the story, providing information on transport, fate, and effects of the Deepwater Horizon oil release and subsequent recovery of the Gulf of Mexico ecosystems.

  5. Targeted Radiation Therapy for Cancer Initiative

    Science.gov (United States)

    2017-11-01

    AWARD NUMBER: W81XWH-08-2-0174 TITLE: Targeted Radiation Therapy for Cancer Initiative PRINCIPAL INVESTIGATOR: Dusten Macdonald, MD...for Cancer Initiative 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Dusten Macdonald, MD 5d. PROJECT NUMBER...Cancer Initiative Final Report INTRODUCTION: The full potential of radiation therapy has not been realized due to the inability to locate and

  6. 76 FR 25328 - New Mexico Green Initiatives, LLC; Supplemental Notice That Initial Market-Based Rate Filing...

    Science.gov (United States)

    2011-05-04

    ... Mexico Green Initiatives, LLC's application for market-based rate authority, with an accompanying rate... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ER11-3431-000] New Mexico Green Initiatives, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes Request for...

  7. United States-Mexico cross-border health insurance initiatives: Salud Migrante and Medicare in Mexico.

    Science.gov (United States)

    Vargas Bustamante, Arturo; Laugesen, Miriam; Caban, Mabel; Rosenau, Pauline

    2012-01-01

    While U.S. health care reform will most likely reduce the overall number of uninsured Mexican-Americans, it does not address challenges related to health care coverage for undocumented Mexican immigrants, who will remain uninsured under the measures of the reform; documented low-income Mexican immigrants who have not met the five-year waiting period required for Medicaid benefits; or the growing number of retired U.S. citizens living in Mexico, who lack easy access to Medicare-supported services. This article reviews two promising binational initiatives that could help address these challenges-Salud Migrante and Medicare in Mexico; discusses their prospective applications within the context of U.S. health care reform; and identifies potential challenges to their implementation (legal, political, and regulatory), as well as the possible benefits, including coverage of uninsured Mexican immigrants, and their integration into the U.S. health care system (through Salud Migrante), and access to lower-cost Medicare-supported health care for U.S. retirees in Mexico (Medicare in Mexico).

  8. Quantifying uncertainty in Gulf of Mexico forecasts stemming from uncertain initial conditions

    KAUST Repository

    Iskandarani, Mohamed; Le Hé naff, Matthieu; Srinivasan, Ashwanth; Knio, Omar

    2016-01-01

    Polynomial Chaos (PC) methods are used to quantify the impacts of initial conditions uncertainties on oceanic forecasts of the Gulf of Mexico circulation. Empirical Orthogonal Functions are used as initial conditions perturbations with their modal

  9. Merida Initiative: Insight Into U.S. Mexico Relations

    Science.gov (United States)

    2016-09-01

    LEGISLATION IN THE UNITED STATES ....................................................................................................33 E. MEXICO AS...United States and Mexico go far beyond sheer geography.” She goes on to say, “Bound by economic, environmental , cultural, familial, security, and...attribute the rise in prevalence of Mexican cartels to U.S. seizures of drugs in the Caribbean, essentially closing this route down and forcing Colombian

  10. [Food assistance programs in Mexico, coverage and targeting].

    Science.gov (United States)

    Morales-Ruán, Ma del Carmen; Shamah-Levy, Teresa; Mundo-Rosas, Verónica; Cuevas-Nasu, Lucía; Romero-Martínez, Martín; Villalpando, Salvador; Rivera-Dommarco, Juan Ángel

    2013-01-01

    To describe the distribution of social food assistance programs in Mexico. Information about 36 150 households from the National Health and Nutrition Survey (ENSANUT 2012) was included. The distribution of the social assistance food programs by characteristics as rural/urban locality, country region, ethnicity, socioeconomic level and nutritional status was observed. At the national level, food assistance programs with the greater coverage are Oportunidades (reaching 18.8% of the population), Liconsa (milk distribution, 9.7%) and School Breakfasts (12.2%). The program that assists in the best way the target population is Oportunidades, where 75% of its beneficiaries belong to the "low" and "lower" socioeconomic levels, in contrast to Liconsa and School Breakfasts programs, where only 42% and 55% of the beneficiaries are in such levels, respectively. Current focus and application of the food assistance programs must be adjusted under the perspective of wellness, health and nutrition of the children population.

  11. [Initial experience in robot-assisted colorectal surgery in Mexico].

    Science.gov (United States)

    Villanueva-Sáenz, Eduardo; Ramírez-Ramírez, Moisés Marino; Zubieta-O'Farrill, Gregorio; García-Hernández, Luis

    Colorectal surgery has advanced notably since the introduction of the mechanical suture and the minimally invasive approach. Robotic surgery began in order to satisfy the needs of the patient-doctor relationship, and migrated to the area of colorectal surgery. An initial report is presented on the experience of managing colorectal disease using robot-assisted surgery, as well as an analysis of the current role of this platform. A retrospective study was conducted in order to review five patients with colorectal disease operated using a robot-assisted technique over one year in the initial phase of the learning curve. Gender, age, diagnosis and surgical indication, surgery performed, surgical time, conversion, bleeding, post-operative complications, and hospital stay, were analysed and described. A literature review was performed on the role of robotic assisted surgery in colorectal disease and cancer. The study included 5 patients, 3 men and 2 women, with a mean age of 62.2 years. Two of them were low anterior resections with colorectal primary anastomoses, one of them extended with a loop protection ileostomy, a Frykman-Goldberg procedure, and two left hemicolectomies with primary anastomoses. The mean operating time was 6hours and robot-assisted 4hours 20minutes. There were no conversions and the mean hospital stay was 5 days. This technology is currently being used worldwide in different surgical centres because of its advantages that have been clinically demonstrated by various studies. We report the first colorectal surgical cases in Mexico, with promising results. There is enough evidence to support and recommend the use of this technology as a viable and safe option. Copyright © 2016 Academia Mexicana de Cirugía A.C. Publicado por Masson Doyma México S.A. All rights reserved.

  12. 76 FR 23548 - Galvanized Steel Wire From the People's Republic of China and Mexico: Initiation of Antidumping...

    Science.gov (United States)

    2011-04-27

    ... Wire From the People's Republic of China and Mexico: Initiation of Antidumping Duty Investigations... Imports of Galvanized Steel Wire from the People's Republic of China (the PRC) and Mexico and... Initiation Checklist at 6-10 and Mexico Initiation Checklist at 6- 10. Export Price The PRC For the PRC...

  13. Final report to DOE [Global guardianship initiative in southern Mexico

    Energy Technology Data Exchange (ETDEWEB)

    None

    2000-07-01

    The objective of this project is to establish models for community renewable energy deployment as a strategy for protected area management and an alternative to grid extension in developing countries in Latin America and Asia. Working together with the Nature Conservancy, the Center for Resource Solutions chose Southern Mexico and its 10 protected areas to launch this program. DOE funds supported Phase One activities: establishment of an advisory committee and selection of six to ten communities for renewable energy plans.

  14. Mexico City Air Quality Research Initiative; Volume 5, Strategic evaluation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    Members of the Task HI (Strategic Evaluation) team were responsible for the development of a methodology to evaluate policies designed to alleviate air pollution in Mexico City. This methodology utilizes information from various reports that examined ways to reduce pollutant emissions, results from models that calculate the improvement in air quality due to a reduction in pollutant emissions, and the opinions of experts as to the requirements and trade-offs that are involved in developing a program to address the air pollution problem in Mexico City. The methodology combines these data to produce comparisons between different approaches to improving Mexico City`s air quality. These comparisons take into account not only objective factors such as the air quality improvement or cost of the different approaches, but also subjective factors such as public acceptance or political attractiveness of the different approaches. The end result of the process is a ranking of the different approaches and, more importantly, the process provides insights into the implications of implementing a particular approach or policy.

  15. Three Years of the New Mexico Laptop Learning Initiative (NMLLI): Stumbling toward Innovation

    Science.gov (United States)

    Rutledge, David; Duran, James; Carroll-Miranda, Joseph

    2007-01-01

    This article presents qualitative results of the first three years of the New Mexico Laptop Learning Initiative (NMLLI). Results suggest that teachers, students, and their communities support this initiative to improve student learning. Descriptive statistics were used during year two to further understand how the laptops were being used by…

  16. 76 FR 39850 - Seamless Refined Copper Pipe and Tube From Mexico: Notice of Initiation of Antidumping Duty New...

    Science.gov (United States)

    2011-07-07

    ... and Tube From Mexico and the People's Republic of China: Antidumping Duty Orders and Amended Final... copper pipe and tube from Mexico exported by GD, for the period November 22, 2010, through April 30, 2011... and Tube From Mexico: Notice of Initiation of Antidumping Duty New Shipper Review AGENCY: Import...

  17. Mexico.

    Science.gov (United States)

    Semaan, Leslie

    The text explores Mexico's history, geography, art, religion, and lifestyles in the context of its complex economy. The text focuses on Mexico's economy and reasons for its current situation. Part I of this teaching unit includes: Teacher Overview, Why Study Mexico, Mexico Fact Sheet, Map of Mexico, the Land and Climate, History, Government,…

  18. 77 FR 3152 - New Mexico: Final Authorization of State-Initiated Changes and Incorporation-by-Reference of...

    Science.gov (United States)

    2012-01-23

    ... relations, Penalties, Reporting and recordkeeping requirements, Water pollution control, Water supply... Mexico: Final Authorization of State-Initiated Changes and Incorporation-by-Reference of State Hazardous.... SUMMARY: During a review of New Mexico's regulations, the EPA identified a variety of State-initiated...

  19. Influence of Translation Initiation on Organellar Protein Targeting in Arabidopsis

    Energy Technology Data Exchange (ETDEWEB)

    Sally A. Mackenzie

    2011-04-18

    A primary focus of the Mackenzie laboratory is the elucidation of processes and machinery for mitochondrial genome maintenance and transmission in higher plants. We have found that numerous organellar DNA maintenance components in plants appear to be dual targeted to mitochondria and plastids. Of particular interest was the observation that some twin (tandemly arrayed) dual targeting presequences appeared to utilize non-AUG alternative translation initiation, allowing for multiple translation starts at a single gene. Two aspects of this phenomenon were of particular interest: (1) Alternative translation initiation might provide a mechanism to regulate protein targeting temporally and spatially, a possibility that had not been demonstrated previously, and (2) alternative translation initiation might occur in genes involved in nuclear-controlled mitochondrial genome recombination, thought to be exclusively mitochondrial in their function. During the course of this research, we pursued three aims, with an emphasis on two specific genes of interest: POLgamma2, an organellar DNA polymerase, and MSH1, a MutS homolog thought to participate in mitochondrial, but not plastid, genome recombination surveillance. Our aims were to (1) Identify additional genes within Arabidopsis and other genomes that employ non-AUG alternative translation initiation, (2) Locate sequences upstream to the annotated AUG that confer alternative non-AUG translation initiation activity, and (3) Identify cis and trans factors that influence start site selection in genes with non-AUG starts. Toward these ends, we have shown that non-AUG initiation occurs in a number of genes, likely influencing targeting behavior of the protein. We have also shown that start site selection is strongly influenced by Kozak consensus sequence environment, indicating that alternative translation initiation in plants occurs by relaxation of ribosome scanning.

  20. Cross-border migration and initiation of others into drug injecting in Tijuana, Mexico.

    Science.gov (United States)

    Rafful, Claudia; Melo, Jason; Medina-Mora, María Elena; Rangel, Gudelia; Sun, Xiaoying; Jain, Sonia; Werb, Dan

    2018-04-01

    Efforts to prevent injection drug use (IDU) are increasingly focusing on the role that people who inject drugs (PWID) play in facilitating the entry of others into this behaviour. This is particularly relevant in settings experiencing high levels of IDU, such as Mexico's northern border region, where cross-border migration, particularly through forced deportation, has been found to increase a range of health and social harms related to injecting. PWID enrolled in a prospective cohort study in Tijuana, Mexico, since 2011 were interviewed semi-annually, which solicited responses on their experiences initiating others into injecting. Univariate and multivariable logistic regression analyses were conducted at the Preventing Injection by Modifying Existing Responses (PRIMER) baseline, with the dependent variable defined as reporting ever initiating others into injection. The primary independent variable was lifetime deportation from the USA to Mexico. Among 532 participants, 14% (n = 76) reported initiating others into injecting, the majority of participants reporting initiating acquaintances (74%, n = 56). In multivariable analyses, initiating others into injecting was independently associated with reporting living in the USA for 1-5 years [adjusted odds ratio (AOR) = 2.42; 95% confidence interval (CI) 1.22-4.79, P = 0.01], and methamphetamine and heroin injection combined (AOR = 3.67; 95% CI 1.11-12.17, P = 0.03). Deportation was not independently associated with initiating others into injecting. The impact of migration needs to be considered within binational programming seeking to prevent the expansion of epidemics of injecting and HIV transmission among mobile populations residing in the Mexico-USA border region. © 2017 Australasian Professional Society on Alcohol and other Drugs.

  1. The Environmental Health/Home Safety Education Project: a successful and practical U.S.-Mexico border initiative.

    Science.gov (United States)

    Forster-Cox, Susan C; Mangadu, Thenral; Jacquez, Benjamín; Fullerton, Lynne

    2010-05-01

    The Environmental Health/Home Safety Education Project (Proyecto de Salud Ambiental y Seguridad en el Hogar) has been developed in response to a wide array of severe and often preventable environmental health issues occurring in and around homes on the U.S.-Mexico border. Utilizing well-trained community members, called promotoras , homes are visited and assessed for potential environmental hazards, including home fire and food safety issues. Data analyzed from project years 2002 to 2005 shows a significant impact in knowledge levels and initial behavior change among targeted participants as it relates to fire and food safety issues. Since the initiation of the project in 1999, hundreds of participants have improved their quality of life by making their homes safer. The project has proven to be sustainable, replicable, flexible, and attractive to funders.

  2. Detection of soil moisture impact in convective initiation in the central region of Mexico

    Science.gov (United States)

    Dolores, Edgar; Caetano, Ernesto

    2017-04-01

    Soil moisture is important for understanding hydrological cycle variability in many regions. Local surface heat and moisture fluxes represent a major source of convective rainfall in Mexico during the summer, driven by positive evaporation-precipitation feedback. The effects of soil moisture are directly reflected in the limitation of evapotranspiration, affecting the development of the planetary boundary layer and, therefore, the initiation and intensity of convective precipitation. This study presents preliminary analysis of the role of soil moisture in convective initiations in central Mexico, for which a methodology for the detection of convective initiations similar to Taylor (2015) has been considered. The results show that the moisture fluxes from the surface influence the development of convection favored by mesoscale circulations at low levels. Initiations are more frequent in regions less humid than their surroundings with the very strong signal during the month of September. The knowledge of the soil predisposition to allow the development of deep convection suggests an alternative tool for the prediction of convective rains in Mexico.

  3. First Trimester Prenatal Care Initiation Among Hispanic Women Along the U.S.-Mexico Border

    OpenAIRE

    Selchau, Katherine; Babuca, Maricela; Bower, Kara; Castro, Yara; Coakley, Eugenie; Flores, Araceli; Garcia, Jonah O.; Reyes, Maria Lourdes F.; Rojas, Yvonne; Rubin, Jason; Samuels, Deanne; Shattuck, Laura

    2017-01-01

    Background First trimester prenatal care (FTPNC) is associated with improved birth outcomes. U.S.-Mexico border Hispanic women have lower FTPNC than non-border or non-Hispanic women. This study aimed to identify (1) what demographic, knowledge and care-seeking factors influence FTPNC among Hispanic women in border counties served by five Healthy Start sites, and (2) what FTPNC barriers may be unique to this target population. Healthy Starts work to eliminate disparities in perinatal health in...

  4. 76 FR 79169 - Power Network New Mexico, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes...

    Science.gov (United States)

    2011-12-21

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ER12-605-000] Power Network New Mexico, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes Request for... Power Network New Mexico, LLC's application for market-based rate authority, with an accompanying rate...

  5. The Initiative to extend Medicare into Mexico: a case study in changing U.S. Health Care Policy

    Directory of Open Access Journals (Sweden)

    Roberto A. Ibarra

    2011-10-01

    Full Text Available This study examines the geo-political activities of interest groups, governments and multinational corporations involved in an initiative to extend Medicare to U.S. retirees residing in Mexico.  If the initiative to change the current Medicare policy succeeds, the relocation of Medicare-eligible populations from the U.S. to Mexico is likely to increase; the U.S. is expected to gain cost-savings for taxpayers on Medicare; Mexico can develop senior-housing and options for long-term care it currently lacks; and foreign-led multinational corporations will increase their profits and dominance, fostering even more privatization in Mexico’s health care sector. By exploring new issues about retirement migration and health this study seeks to gain knowledge about the phenomena in a number of areas.  First, the retirement migration of North Americans to Latin America is an under-studied phenomenon in the fields of social gerontology, migration research, and health policy studies.  Second, the Medicare in Mexico initiative is even less well-known among health policy scholars than the retirement migration phenomenon into Mexico. Yet this initiative is inherently international in scope and involves a number of US-based institutions and interest groups actively promoting the project from within Mexico. Thus, the initiative has important geo-political and socio-economic implications for reforming health care systems in the U.S. and Mexico.

  6. Development of labelled biomolecules for targeted radiotherapy. Mexico

    International Nuclear Information System (INIS)

    Arteaga de Murphy, Consuelo

    2000-01-01

    The scope of the co-ordinated research project (Dec 15 1997) included the following activities: 1) develop coupling techniques using bifunctional chelating agents for monoclonal antibodies and peptides; 2) optimise radiolabelling procedures and reaction parameters using Sm-153 and Re-188; 3) investigate direct methods of labelling monoclonal antibodies and peptides with Re-188; 4) initiate animal distribution studies. The modifications specified for the period 1999/02/15 to 2000/02/14 are as follows: a) continue with the optimisation of Re-188-peptide labelling; b) continue with the work to prepare a kit; c) in-vivo and in-vitro studies; d) Lanreotide labelling. The group formed by researchers from several Mexican institutions have worked together and in different aspects of the CRP in order to fulfil the proposed aims

  7. Quantifying uncertainty in Gulf of Mexico forecasts stemming from uncertain initial conditions

    KAUST Repository

    Iskandarani, Mohamed

    2016-06-09

    Polynomial Chaos (PC) methods are used to quantify the impacts of initial conditions uncertainties on oceanic forecasts of the Gulf of Mexico circulation. Empirical Orthogonal Functions are used as initial conditions perturbations with their modal amplitudes considered as uniformly distributed uncertain random variables. These perturbations impact primarily the Loop Current system and several frontal eddies located in its vicinity. A small ensemble is used to sample the space of the modal amplitudes and to construct a surrogate for the evolution of the model predictions via a nonintrusive Galerkin projection. The analysis of the surrogate yields verification measures for the surrogate\\'s reliability and statistical information for the model output. A variance analysis indicates that the sea surface height predictability in the vicinity of the Loop Current is limited to about 20 days. © 2016. American Geophysical Union. All Rights Reserved.

  8. Analysis of the Activities of Children in Initial Education in Indigenous Communities of Oaxaca, Mexico

    Directory of Open Access Journals (Sweden)

    Julián Jiménez Ramírez

    2016-01-01

    Full Text Available This study provides partial results of a 200-hour intensive training experience (called a diplomado lasting one school year (2011-2012 for 35 indigenous teachers of Initial education who attend children 0 to 3 years old in marginalized communities of Oaxaca, mexico. Children’s spontaneous activities and those planned by teachers, presented through photographs and accompanying teacher’ narratives, are part of the written and photographic evidence submitted by the participants in their final diplomado portfolio of tasks. the purposes of the diplomado were to enrich teachers’communal knowledge and equip them with research skills to investigate and honor the communal practices, forms of governance, and the perspectives of the rural indigenous communities where they teach, in order to generate an authentic, alternative, community-based approach to initial education for babies and toddlers.

  9. Musculoskeletal ultrasound in rheumatology in Korea: targeted ultrasound initiative survey.

    Science.gov (United States)

    Kang, Taeyoung; Wakefield, Richard J; Emery, Paul

    2016-04-01

    In collaboration with the Targeted Ultrasound Initiative (TUI), to conduct the first study in Korea to investigate current practices in ultrasound use among Korean rheumatologists. We translated the TUI Global Survey into Korean and added questions to better understand the specific challenges facing rheumatologists in Korea. To target as many rheumatologists in Korea as possible, we created an on-line version of this survey, which was conducted from March to April 2013. Rheumatologists are in charge of ultrasound in many Korean hospitals. Rheumatologists in hospitals and private clinics use ultrasound to examine between one and five patients daily; they use ultrasound for diagnosis more than monitoring and receive compensation of about US$30-50 per patient. There are marked differences in the rates of ultrasound usage between rheumatologists who work in private practice compared with tertiary hospitals. Korean rheumatologists not currently using ultrasound in their practice appear eager to do so. This survey provides important insights into the current status of ultrasound in rheumatology in Korea and highlights several priorities; specifically, greater provision of formal training, standardization of reporting and accrual of greater experience among ultrasound users. If these needs are addressed, all rheumatology departments in Korea are likely to use ultrasound or have access to it in the future. © 2014 Asia Pacific League of Associations for Rheumatology and Wiley Publishing Asia Pty Ltd.

  10. Teaching Our Own Babies: Teachers' Life Journeys into Community - Based Initial Education in Indigenous Oaxaca, Mexico

    Directory of Open Access Journals (Sweden)

    Lois M. Meyer

    2016-02-01

    Full Text Available In an era when U.S. and Mexican teachers are valued more for their academic achievements than their community-based knowledge and local/ethnic identity (e.g. Teach for America, or its off-shoot, Teach for Mexico, this study provides initial results of a one-year (2011-2012 intensive professional development experience (called a diplomado for 35 indigenous teachers of Initial Education who are “teaching their own babies” in marginalized communities of Oaxaca, Mexico, as documented in portfolios of written and photographic evidence produced by the teachers as their final diplomado product. The goal was to enrich these local teachers' background knowledge and equip them with research skills to investigate and honor the communal practices, governance, and perspectives (known as comunalidad of the rural indigenous communities where they teach, in order to generate an authentic, community-based approach to Initial Education for pregnant mothers, babies and toddlers up to 3 years old – a ground-breaking alternative to the Mexican government’s homogeneous Initial Education approach. Early findings indicate that these Oaxacan indigenous teachers faced a complex of internal and external challenges in this radical, regenerative work: they are young, female, mostly novice teachers, they lack professional preparation, and they have confronted racism throughout their own lives, especially and intensely in Mexican public schools. In the process of documenting communal life and early childhood socialization practices in rural communities where they teach, they confronted their own (often uneasy biculturalism and bilingualism. “Communalizing” early education in indigenous Oaxaca involves reconstructing and revitalizing the indigenous identities and language use of children and teachers alike. Preparing these local indigenous teachers to “teach their own babies” is a challenging but invaluable and achievable task.

  11. Targeting sarcoma tumor-initiating cells through differentiation therapy

    Directory of Open Access Journals (Sweden)

    Dan Han

    2017-05-01

    Full Text Available Human leukocyte antigen class I (HLA-I down-regulation has been reported in many human cancers to be associated with poor clinical outcome. However, its connection to tumor-initiating cells (TICs remains unknown. In this study, we report that HLA-I is down-regulated in a subpopulation of cells that have high tumor initiating capacity in different types of human sarcomas. Detailed characterization revealed their distinct molecular profiles regarding proliferation, apoptosis and stemness programs. Notably, these TICs can be induced to differentiate along distinct mesenchymal lineages, including the osteogenic pathway. The retinoic acid receptor signaling pathway is overexpressed in HLA-1 negative TICs. All-trans retinoic acid treatment successfully induced osteogenic differentiation of this subpopulation, in vitro and in vivo, resulting in significantly decreased tumor formation. Thus, our findings indicate down-regulated HLA-I is a shared feature of TICs in a variety of human sarcomas, and differentiation therapy strategies may specifically target undifferentiated TICs and inhibit tumor formation.

  12. Odour-baited targets to control New World screwworm: A preliminary field study in Mexico

    International Nuclear Information System (INIS)

    Torr, S.J.; Hall, M.J.R.

    1992-01-01

    Biconical, F3 and Wind Oriented (WOT) traps and black cloth targets, baited with swormlure-4, were assessed as catching and killing devices for the New World screwworm fly, Cochliomyia hominivorax, in Mexico. The WOT was significantly better than the other trap designs, with a mean catch 2.7 and 86.4 times better than those of the Biconical and F3, respectively. It was demonstrated that the release of swormlure-4 could be reduced from the standard 10 ml/day to 2 ml/day without a reduction in the numbers of screwworm caught in a WOT. Use of electric nets demonstrated that a visual target was not necessary for the precise location of a swormlure-4 source by screwworm. Target colour was important with respect to the landing response of screwworms on targets: in a two-choice situation, flies landed much more frequently on black than on blue or yellow, and more on these two colours than they did on white. Screwworm tend not to circle a target before landing on it: about 75% of the flies caught on a combination of electrified black target plus electric flanking net were caught on the target. 6 tabs

  13. A collaborative initiative for the containment of antimicrobial resistance in Mexico.

    Science.gov (United States)

    Zaidi, Mussaret B; Dreser, Anahi; Figueroa, Inda Marcela

    2015-04-01

    Antimicrobial resistance exacts worldwide an increasingly significant clinical and economic toll. Despite the international calls for urgent action, antimicrobial use and resistance have been low on the Mexican government's policy agenda. In early 2010, a multidisciplinary group of experts launched a national initiative for containment of antimicrobial resistance that was endorsed by major medical, veterinary and public health institutions. The initiative called for seven priority actions including the creation of an ad hoc intersectoral advisory group, a requirement that human and veterinary antibiotics be dispensed only with prescription, and the establishment of effective surveillance systems. A consensus document was disseminated among key decision-makers at the ministries of Health and Agriculture and the legislature. The Ministry of Health (MoH) enacted a decree effective as of August 2010, which enforced the regulations that required medical prescriptions for the sale of human antibiotics. While the information disseminated by the MoH did focus on the dangers of self-medication, it failed to highlight the inherent perils of antibiotic resistance or the consequences of antibiotic use in food-animals. Following the decree, there was a surge of medical offices controlled by retail pharmacies. In the veterinary sector, voluntary guidelines were developed for good husbandry practices, including antibiotic use in food animals; five antimicrobials for use in food-animals were banned. No intersectoral advisory group or surveillance systems were established. This study describes a bottom-top approach in Mexico for the development of a national strategy to improve antibiotic use and contain antimicrobial resistance. Its experiences suggest that, in countries such as Mexico that lack strong regulatory systems and surveillance capacities, a more systemic approach is warranted. Future efforts should begin with early involvement of key stakeholders and informing policy

  14. Mexico.

    Science.gov (United States)

    1993-01-01

    The background notes on Mexico provide text and recent statistical information on the geography, population, government, economy, and foreign relations, specifically the North American Free Trade Agreement with US. The 1992 population is estimated at 89 million of which 60% are mestizo (Indian-Spanish), 30% are American Indian, 9% are Caucasian, and 1% are other. 90% are Roman Catholic. There are 8 years of compulsory education. Infant mortality is 30/1000 live births. Life expectancy for males is 68 years and 76 years for females. The labor force is comprised of 30% in services, 24% in agriculture and fishing, 19% in manufacturing, 13% in commerce, 7% in construction, 4% in transportation and communication, and .4% in mining. There are 31 states and a federal district. Gross domestic product (GDP) per capita was $3200 in 1991. Military expenditures were .5% of GDP in 1991. The average inflation rate is 19%. Mexico City with 20 million is the largest urban center in the world. In recent years, the economy has been restructured with market oriented reforms; the result has been a growth of GDP of 3.6% in 1991 from 2% in 1987. Dependence on oil exports has decreased. There has been privatization and deregulation of state-owned companies. Subsidies to inefficient companies have been stopped. Tariff rates were reduced. The financial debt has been reduced and turned into a surplus of .8% in 1992. Mexico's foreign debt has been reduced from its high in 1987 of $107 billion. Agricultural reforms have been ongoing for 50 years. Land was redistributed, but standards of living and productivity have improved only slightly. Rural land tenure regulations have been changed, and other economic reforms are expected. Mexico engages in ad hoc international groups and is selective about membership in international organizations.

  15. Canada-United States-Mexico Trilateral Cooperation on Childhood Obesity Initiative

    Directory of Open Access Journals (Sweden)

    Cristina Rabadán-Diehl

    Full Text Available ABSTRACT Childhood obesity is an important public health problem that affects countries in the Americas. In 2014, Pan American Health Organization (PAHO Member States agreed on a Plan of Action for the Prevention of Obesity in Children and Adolescents in an effort to address the impact of this disorder in the Americas region. The interventions laid out in this regional plan are multi-faceted and require multi-sectoral partnerships. Building on a strong history of successful trilateral collaboration, Canada, Mexico, and the United States formed a partnership to address the growing epidemic of childhood obesity in the North American region. This collaborative effort, known as the Trilateral Cooperation on Childhood Obesity Initiative, is the first initiative in the region to address chronic noncommunicable diseases by bringing together technical and policy experts, with strong leadership and support from the secretaries and ministers of health. The Initiative’s goals include increasing levels of physical activity and reducing sedentary behavior through 1 increased social mobilization and citizen engagement, 2 community- based outreach, and 3 changes to the built (man-made environment. This article describes the background and development process of the Initiative; specific goals, activities, and actions achieved to date; and opportunities and next steps. This information may be useful for those forming other partnerships designed to address childhood obesity or other complex public health challenges in the region.

  16. First Trimester Prenatal Care Initiation Among Hispanic Women Along the U.S.-Mexico Border.

    Science.gov (United States)

    Selchau, Katherine; Babuca, Maricela; Bower, Kara; Castro, Yara; Coakley, Eugenie; Flores, Araceli; Garcia, Jonah O; Reyes, Maria Lourdes F; Rojas, Yvonne; Rubin, Jason; Samuels, Deanne; Shattuck, Laura

    2017-12-01

    Background First trimester prenatal care (FTPNC) is associated with improved birth outcomes. U.S.-Mexico border Hispanic women have lower FTPNC than non-border or non-Hispanic women. This study aimed to identify (1) what demographic, knowledge and care-seeking factors influence FTPNC among Hispanic women in border counties served by five Healthy Start sites, and (2) what FTPNC barriers may be unique to this target population. Healthy Starts work to eliminate disparities in perinatal health in areas with high poverty and poor birth outcomes. Methods 403 Hispanic women of reproductive age in border communities of California, Arizona, New Mexico and Texas were surveyed on knowledge and behaviors related to prenatal care (PNC) and basic demographic information. Chi square analyses and logistic regressions were used to identify important relationships. Results Chi square analyses revealed that primiparous women were significantly less likely to start FTPNC than multiparous women (χ 2 = 6.8372, p = 0.0089). Women with accurate knowledge about FTPNC were more likely to obtain FTPNC (χ 2  = 29.280, p < .001) and more likely to have seen a doctor within the past year (χ 2  = 5.550, p = .018). Logistic regression confirmed that multiparity was associated with FTPNC and also that living in Texas was negatively associated with FTPNC (R 2  = 0.066, F(9,340) = 2.662, p = .005). Among 27 women with non-FTPNC, barriers included late pregnancy recognition (n = 19) and no medical insurance (n = 5). Conclusions This study supports research that first time pregnancies have lower FTPNC, and demonstrated a strong association between delayed PNC and late pregnancy recognition. Strengthened investments in preconception planning could improve FTPNC in this population.

  17. Mexico

    International Nuclear Information System (INIS)

    2003-06-01

    This document summarizes the key energy data for Mexico: 1 - energy organizations and policy: Ministry of energy (SENER), Comision Reguladora de Energia (CRE), Ministry of Finances, Ministry of trade and industrial development (SECOFI), national commission for energy savings (CONAE); 2 - companies: federal commission of electricity (CFE), Minera Carbonifera Rio Escondido (MICARE - coal), Pemex (petroleum); 3 - energy production: resources, electric power, petroleum, natural gas; 4 - energy consumption; 5 - stakes and perspectives. Some economic and energy indicators are summarized in a series of tables: general indicators, supply indicators (reserves, refining and electric capacity, energy production, foreign trade), demand indicators (consumption trends, end use, energy independence, energy efficiency, CO 2 emissions), energy status per year and per energy source. (J.S.)

  18. Rural Revitalization in New Mexico: A Grass Roots Initiative Involving School and Community

    Science.gov (United States)

    Pitzel, Gerald R.; Benavidez, Alicia C.; Bianchi, Barbara C.; Croom, Linda L.; de la Riva, Brandy R.; Grein, Donna L.; Holloway, James E.; Rendon, Andrew T.

    2007-01-01

    The Rural Education Bureau of the New Mexico Public Education Department has established a program to address the special needs of schools and communities in the extensive rural areas of the state. High poverty rates, depopulation and a general lack of viable economic opportunity have marked rural New Mexico for decades. The program underway aims…

  19. Mitochondria: An intriguing target for killing tumour-initiating cells

    Czech Academy of Sciences Publication Activity Database

    Yan, B.; Dong, L.; Neužil, Jiří

    2016-01-01

    Roč. 26, JAN 2016 (2016), s. 86-93 ISSN 1567-7249 R&D Projects: GA MŠk(CZ) ED1.1.00/02.0109 Institutional support: RVO:86652036 Keywords : Tumour-initiating cells * ALPHA-TOCOPHERYL SUCCINATE * Therapeutic resistance * Mitochondria Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 3.704, year: 2016

  20. The Gulf of Mexico Research Initiative: Managing a Multidisciplinary Data Explosion

    Science.gov (United States)

    Howard, M. K.; Gibeaut, J. C.; Reed, D.

    2011-12-01

    On April 20, 2010 the Deepwater Horizon drilling unit located in the northeastern Gulf of Mexico, experienced a catastrophic wellhead blowout. Roughly 5 billion barrels of oil and 1 million U.S. gallons of dispersant were released near the wellhead over the next three months. Within weeks of the blowout, BP announced the Gulf of Mexico Research Initiative (GRI) and pledged 50M/yr over 10 years for independent scientific research on the spill's impact on the ecosystem. Two months after the blowout three institutions were awarded a total of 25M in fast-track grants (Louisiana State University, Northern Gulf Institute, and Florida Institute of Oceanography). Soon after the Alabama Marine Environmental Sciences Consortium and the National Institutes of Health were awarded 5M and 10M, respectively. These five institutions began to generate data almost immediately. First year grants funded 100's of researchers from nearly 100 research units. Their activities included numerical modeling, field data collection, and laboratory experiments. Measured parameters included those associated with chemical analyses of oil, gas, and dispersants, studies of bacteria, plants and animals -from phytoplankton to marsh grasses, from zooplankton to cetaceans. Studies were conducted from estuaries to the deep Gulf, from atmosphere to sediments. Parameters from physical oceanography, marine meteorology, and biogeochemistry were measured in abundance. Additionally, impact studies on human mental, physical health and businesses were made. Proposals for years 2-4 of the program were to be awarded in August 2011 supporting 4-8 research consortia. Consortia may have up to 20 named researchers. In aggregate, these studies yielded a multidisciplinary data explosion. Following the fast-track awards the GRI Administrative Unit (AU) was established and a data management activity initiated. That activity became the GRI Information and Data Cooperative (GRIIDC). "Cooperative" emphasizes the

  1. Targeted initiatives. Support for nuclear engineering education in the USA

    International Nuclear Information System (INIS)

    Gutteridge, John

    2001-01-01

    Recruitment and education of a new generation of nuclear engineers stands to benefit in the USA from a range of programmes involving governmental bodies, universities, and industry groups. They are part of efforts to attract more students to consider and prepare for careers in the nuclear industry, and to provide financial support for nuclear research and education. Career prospects in the nuclear field are brightening. The demand for nuclear engineers and nuclear trained personnel is on the rise as the new century opens. During the past year several studies were completed in an attempt to ascertain the problems in nuclear engineering education and define initiatives to address these problems

  2. Northern Gulf Littoral Initiative (NGLI), Geology and Physical Properties of Marine Sediments in the N.E. Gulf of Mexico: Data Report

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Northern Gulf Littoral Initiative (NGLI), Geology and Physical Properties of Marine Sediments in the N.E. gulf of Mexico: Data Report, was produced by the U.S....

  3. The Gulf of Mexico Research Initiative Information and Data Cooperative: Multidisciplinary data management from the ground up

    Science.gov (United States)

    Showalter, L. M.; Gibeaut, J. C.

    2015-12-01

    As more journals and funding organizations require data to be made available, more and more scientists are being exposed to the world of data science, metadata development, and data standards so they can ensure future funding and publishing success. The Gulf of Mexico Research Initiative Information and Data Cooperative (GRIIDC) is the vehicle by which the Gulf of Mexico Research Initiative (GOMRI) is making all data collected in this program publically available. This varied group of researchers all have different levels of experience with data management standards and protocols, thus GRIIDC has evolved to embrace the cooperative nature of our work and develop a number of tools and training materials to help ensure data managers and researchers in the GoMRI program are submitting high quality data and metadata that will be useful for years to come. GRIIDC began with a group of 8 data managers many of which had only ever managed their own data, who were then expected to manage the data of a large group of geographically distant researchers. As the program continued to evolve these data managers worked with the GRIIDC team to help identify and develop much needed resources for training and communication for themselves and the scientists they represented. This essential cooperation has developed a team of highly motivated scientists, computer programmers and data scientists who are working to ensure a data and information legacy that promotes continual scientific discovery and public awareness of the Gulf of Mexico Ecosystem and beyond.

  4. Introduction to the Yogurt in Nutrition Initiative at the First Symposium of Yogurt in Mexico: The Balanced Diet Initiative.

    Science.gov (United States)

    Tovar, Armando R; Herrera, Guadalupe

    2017-01-01

    In some European countries, yogurt consumption is common. However, such consumption is not common in Latin America, particularly in Mexico, partially because of the lack of a cultural tradition of consuming yogurt. Moreover, we also know that little information about the health benefits associated with yogurt consumption has been provided to the Mexican population. Thus, there is an immediate need to provide, at least to the nutrition community in the country, current scientific evidence about the health benefits of yogurt, with the aim that yogurt be included as part of the functional foods recommended to the population. Currently, extensive research has been conducted to investigate the mechanisms through which yogurt generates beneficial effects. Gut microbiota appear to be an important factor that can be modified by dietary prebiotics, as well as probiotics such as yogurt. The prevention or attenuation of gut microbiota dysbiosis is now associated with improvements observed in individuals with metabolic syndrome and cardiovascular disease. Thus, it is important to establish guidelines for the consumption of dairy products, including yogurt. Such guidelines are necessary to increase the consumption of dairy products in Mexico and other countries. © 2017 American Society for Nutrition.

  5. Hydrothermal Petroleum in Active Continental Rift: Lake Chapala, Western Mexico, Initial Results.

    Science.gov (United States)

    Zarate-del Valle, P. F.; Simoneit, B. R.; Ramirez-Sanchez, H. U.

    2003-12-01

    Lake Chapala in western Mexico is located partially in the Citala Rift, which belongs to the well-known neotectonic Jalisco continental triple junction. The region is characterized by active volcanism (Ceboruco, Volcan de Fuego), tectonic (1995 earthquake, M=8, 40-50 mm to SW) and hydrothermal (San Juan Cosala & Villa Corona spas and La Calera sinter deposit) activities. Hydrothermal petroleum has been described in active continental rift (East African Rift) and marine spreading zones (Guaymas Basin, Gulf of California). In 1868 the Mexican local press reported that manifestations of bitumen were appearing in front of the Columba Cap on the mid south shore of Lake Chapala. This bitumen is linked to the lake bottom and when the water level decreases sufficiently it is possible to access these tar bodies as islands. Because of these manifestations the Mexican oil company (PEMEX) drilled an exploration well (2,348m) at Tizapan El Alto without success. Hydrothermal activity is evident in the tar island zone as three in-shore thermal springs (26.8 m depth, 48.5° C, pH 7.8 and oriented N-S). The preliminary analyses by GC-MS of the tar from these islands indicate hydrothermal petroleum derived from lake sedimentary organic matter, generated at low temperatures (150° -200° C). The tars contain no n-alkanes, no PAH or other aromatics, but a major UCM of branched and cyclic hydrocarbons and mature biomarkers derived from lacustrine biota. The biomarkers consist of mainly 17α (H),21β (H)-hopanes ranging from C27 to C34 (no C28), gammacerane, tricyclic terpanes (C20-C26), carotane and its cracking products, and drimanes (C14-C16). The biomarker composition indicates an organic matter source from bacteria and algae, typical of lacustrine ecosystems. 14C dating of samples from two tar islands yielded ages exceeding 40 kyrs, i.e., old carbon from hydrothermal/tectonic remobilization of bitumen from deeper horizons to the surface. The occurrence of hydrothermal petroleum in

  6. The Gulf of Mexico Research Initiative: A Funding Model for Science, Engineering, and Technology

    Science.gov (United States)

    Colwell, R. R.

    2016-12-01

    The Deepwater Horizon oil spill, a massive ecological event, resulted in the tragic loss of 11 lives, and an environmental release of more than 130 million gallons of crude oil. Approximately 1.8 million gallons of dispersants were used in remediation efforts. An immediate response by BP was to establish a ten-year research program, with funding of 500 million. The funding was to determine the impact and long-term ecological and public health effects of oil spills and to develop improved preparation in the event of future oil or gas release into the environment. This Gulf of Mexico Research Initiative (GoMRI), established by BP, provided independent leadership for both the program and administration of the 500 million funding, and the Research Board provides oversight, assisted by excellent staff. The Research Board of the GoMRI comprises twenty scientists, many of whom have prior scientific research administrative expertise. The Research Board, in accordance with its charge, develops research programs and carries out their evaluation and oversight, employing the peer review and operational principles of the National Science Foundation and the National Academies of Science. With these guiding principles, the Research Board established procedures for conflict of interest oversight and requesting and evaluating research programs. It has also focused on communicating the research findings accurately and responsibly. The GoMRI Research Board operates with transparency and ensures availability of all scientific results and data. GoMRI, currently midway through its 10-year mandate, has funded more than 3,000 scientists, representing 278 institutions in 42 states and 17 countries, who have produced more than 1,000 peer-reviewed publications to date. The Research Board is exploring mechanisms by which the GoMRI science findings can be communicated to the broader community and the public and to continue availability of data when the program has ended. A major contribution

  7. Complete fabrication of target experimental chamber and implement initial target diagnostics to be used for the first target experiments in NDCX-1

    International Nuclear Information System (INIS)

    Bieniosek, F.M.; Bieniosek, F.M.; Dickinson, M.R.; Henestroza, E.; Katayanagi, T.; Jung, J.Y.; Lee, C.W.; Leitner, M.; Ni, P.; Roy, P.; Seidl, P.; Waldron, W.; Welch, D.

    2008-01-01

    The Heavy Ion Fusion Science Virtual National Laboratory (HIFS-VNL) has completed the fabrication of a new experimental target chamber facility for future Warm Dense Matter (WDM) experiments, and implemented initial target diagnostics to be used for the first target experiments in NDCX-1. The target chamber has been installed on the NDCX-I beamline. This achievement provides to the HIFS-VNL unique and state-of-the-art experimental capabilities in preparation for the planned target heating experiments using intense heavy ion beams

  8. Identifying and characterizing transboundary aquifers along the Mexico-US border: An initial assessment

    Science.gov (United States)

    Sanchez, Rosario; Lopez, Victoria; Eckstein, Gabriel

    2016-04-01

    The transboundary nature of water dividing Mexico and the United States (U.S.) transforms the entire border region into an instrument of cooperation, a source of conflict, a national security issue, and an environmental concern. Reasonable data collection and research analysis have been conducted for surface waters by joint governmental institutions and non-governmental bodies. However, with the exception of the U.S. Transboundary Assessment Act Program (TAAP) (focusing on the Hueco Bolson, Mesilla Bolson, San Pedro and Santa Cruz aquifers), there is no comparable research, institutional development, or assessment of transboundary groundwater issues on the frontier. Moreover, data collection and methodologies vary between the two countries, there is no broadly accepted definition of the transboundary nature of an aquifer, and available legal and policy frameworks are constrained by non-hydrological considerations. Hence, there is a conceptual and institutional void regarding transboundary groundwater resources between Mexico and the U.S. The purpose of this paper is to bridge this void and characterize transboundary aquifers on the Mexico-US border. It reviews existing international frameworks for identifying hydrological and social criteria that characterize an aquifer as transboundary. It then assesses data from both countries to propose where and which aquifers could be considered transboundary. Finally, the paper proposes an agenda for assessing Mexico-US transboundary aquifers as a means for improving groundwater management in the border region.

  9. Quality Improvement Initiative in School-Based Health Centers across New Mexico

    Science.gov (United States)

    Booker, John M.; Schluter, Janette A.; Carrillo, Kris; McGrath, Jane

    2011-01-01

    Background: Quality improvement principles have been applied extensively to health care organizations, but implementation of quality improvement methods in school-based health centers (SBHCs) remains in a developmental stage with demonstration projects under way in individual states and nationally. Rural areas, such as New Mexico, benefit from the…

  10. An Analysis of Current Energy Policy Initiatives in New Mexico. What are the Potential Impacts to the State's Water Resources?

    Science.gov (United States)

    Klise, G. T.; Hart, W. E.; Kobos, P. H.; Malczynski, L. A.; Tidwell, V. C.

    2008-12-01

    Population in New Mexico is increasing rapidly with recent projections showing that the state will add more than 1 million people by 2035. This growth will create a demand for additional energy and water supplies that have yet to be developed. New Mexico currently exports about 50% of the energy generated within the state to neighboring states, and existing power plants predominately utilize traditional fossil fuels such as coal, oil and natural gas. Because traditional electric generation technologies utilize large quantities of water, New Mexico can also be seen as exporting water for the benefit of electricity consumed in neighboring states. As it is, both surface water and groundwater supplies are stretched thin and these internal and external stresses stemming from population growth will have a substantial impact on the state's water resources. In 2004, the Governor laid out a plan to make New Mexico a "Clean Energy State" by implementing renewable portfolio standards, developing renewable energy transmission infrastructure, creating an alternative energy innovation fund and creating state specific tax credits for renewable energy production and manufacturing. Recent work in the National Energy-Water Roadmap has pointed out that certain renewable sources of energy utilize less water than traditional power plants, and technological fixes to existing power plants will result in less water consumption. If New Mexico carries out its energy initiative, what will be the impacts to the state's water resources? Will it be possible to meet competing demands for this water? These questions and others will be analyzed in a decision-support tool that can look at the connection between both the physical and economic systems to see what the tradeoffs might be as a result of specific policy decisions. The ability to plan for future energy needs and understanding potential impacts to the state's limited water resources will be an invaluable tool for decision-makers in New

  11. Canada-United States-Mexico Trilateral Cooperation on Childhood Obesity Initiative.

    Science.gov (United States)

    Rabadán-Diehl, Cristina; Safdie, Margarita; Rodin, Rachel

    2016-08-01

    Childhood obesity is an important public health problem that affects countries in the Americas. In 2014, Pan American Health Organization (PAHO) Member States agreed on a Plan of Action for the Prevention of Obesity in Children and Adolescents in an effort to address the impact of this disorder in the Americas region. The interventions laid out in this regional plan are multi-faceted and require multi-sectoral partnerships. Building on a strong history of successful trilateral collaboration, Canada, Mexico, and the United States formed a partnership to address the growing epidemic of childhood obesity in the North American region. This collaborative effort, known as the Trilateral Cooperation on Childhood Obesity Initiative, is the first initiative in the region to address chronic noncommunicable diseases by bringing together technical and policy experts, with strong leadership and support from the secretaries and ministers of health. The Initiative's goals include increasing levels of physical activity and reducing sedentary behavior through 1) increased social mobilization and citizen engagement, 2) community- based outreach, and 3) changes to the built (man-made) environment. This article describes the background and development process of the Initiative; specific goals, activities, and actions achieved to date; and opportunities and next steps. This information may be useful for those forming other partnerships designed to address childhood obesity or other complex public health challenges in the region. RESUMEN La obesidad infantil es un problema de salud pública importante que afecta a los países de las Américas. En el 2014, los Estados Miembros de la Organización Panamericana de la Salud (OPS) acordaron un Plan de acción para la prevención de la obesidad en la niñez y la adolescencia con el fin de hacer frente a las repercusiones de este trastorno en la Región de las Américas. Las intervenciones que componen este plan regional son multifacéticas y

  12. PERSPECTIVES OF TEACHER TRAINING AND INITIAL LITERACY IMPLIED IN EDUCATIONAL PROGRAMS OF THE NORMAL SCHOOLS OF MEXICO

    OpenAIRE

    Efrén Viramontes Anaya; Marivel Gutiérrez Fierro; y Luz Divina Núñez Si-fuentes

    2013-01-01

    Introduction. The stage or phase of this research project is intended to perform an analysis of approaches for teacher ́s training and early literacy of current language programs in Mexico ́s teacher education. The central con-tent of the document contains the analysis of approaches of teachers ́ trai-ning and initial literacy that lie behind educational programs. The theoretical approach is supported by Pérez Gómez (1996) and in the field of literacy in Ferreiro and Teberobsky (2007) and...

  13. On the first occupational medicine initiatives in Mexico: The Real del Monte miners’ hospital.

    Science.gov (United States)

    Gómez, José Luis; Rodríguez-Paz, Carlos Agustín

    2018-01-01

    Despite the legislation of Otto von Bismarck (1815-1898) on social security rights formulated in 1883 in Germany where it is stated that it is the duty of the State to promote the welfare of all members of society, particularly the weakest and most needy, using the means available to them, and the proposals of laws against accidents issued on April 30, 1904 in the State of Mexico in 1904, in the Mexico of the Porfirio Díaz era, providing workers with formal medical care was not contemplated, except in the case of some railway companies, hospitals for the care of patients with occupational diseases were not built. One of these exceptions was the Hospital del Mineral del Real del Monte de Pachuca, founded in the late nineteenth century and after the mining company passed to the Americans in 1906, it was agreed that the company acquired the hospital and equated it with the medical and surgical advances of the time for immediate care of injuries, especially of the orthopedic type, which enabled not only the healing of wounds, but also rehabilitation. This hospital is one of the oldest in Mexico with regard to three disciplines: orthopedics, occupational medicine and rehabilitation. It ceased to operate in 1982, and currently it is a museum with a rich collection of documents and instruments related to the aforementioned disciplines. Copyright: © 2018 SecretarÍa de Salud.

  14. Mexico City air quality research initiative. Volume IV. Characterization and measurement

    Energy Technology Data Exchange (ETDEWEB)

    Mauzy, A. [ed.

    1994-04-01

    This volume describes the methods and the data gathered in an attempt to measure and characterize the meteorological factors and the concentration of different pollutants in the Mexico City Metropolitan Area. The main objective of this document was to provide input for the simulation models and to obtain information that could be used to test and improve the models` performance. Four field campaigns were conducted, as well as routine monitoring, in order to obtain a database of atmospheric dynamics and air pollution characteristics. Sections include Airborne measurements, Remote sensing measurements, and Traditional (in situ) measurements.

  15. Local participation in biodiversity conservation initiatives: a comparative analysis of different models in South East Mexico.

    Science.gov (United States)

    Méndez-López, María Elena; García-Frapolli, Eduardo; Pritchard, Diana J; Sánchez González, María Consuelo; Ruiz-Mallén, Isabel; Porter-Bolland, Luciana; Reyes-Garcia, Victoria

    2014-12-01

    In Mexico, biodiversity conservation is primarily implemented through three schemes: 1) protected areas, 2) payment-based schemes for environmental services, and 3) community-based conservation, officially recognized in some cases as Indigenous and Community Conserved Areas. In this paper we compare levels of local participation across conservation schemes. Through a survey applied to 670 households across six communities in Southeast Mexico, we document local participation during the creation, design, and implementation of the management plan of different conservation schemes. To analyze the data, we first calculated the frequency of participation at the three different stages mentioned, then created a participation index that characterizes the presence and relative intensity of local participation for each conservation scheme. Results showed that there is a low level of local participation across all the conservation schemes explored in this study. Nonetheless, the payment for environmental services had the highest local participation while the protected areas had the least. Our findings suggest that local participation in biodiversity conservation schemes is not a predictable outcome of a specific (community-based) model, thus implying that other factors might be important in determining local participation. This has implications on future strategies that seek to encourage local involvement in conservation. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Mexico City air quality research initiative. Volume 2, Problem definition, background, and summary of prior research

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    Air pollution in Mexico City has increased along with the growth of the city, the movement of its population, and the growth of employment created by industry. The main cause of pollution in the city is energy consumption. Therefore, it is necessary to take into account the city`s economic development and its prospects when considering the technological relationships between well-being and energy consumption. Air pollution in the city from dust and other particles suspended in the air is an old problem. However, pollution as we know it today began about 50 years ago with the growth of industry, transportation, and population. The level of well-being attained in Mexico City implies a high energy use that necessarily affects the valley`s natural air quality. However, the pollution has grown so fast that the City must act urgently on three fronts: first, following a comprehensive strategy, transform the economic foundation of the city with nonpolluting activities to replace the old industries, second, halt pollution growth through the development of better technologies; and third, use better fuels, emission controls, and protection of wooded areas.

  17. Non-injection Drug Use and Injection Initiation Assistance among People Who Inject Drugs in Tijuana, Mexico.

    Science.gov (United States)

    Ben Hamida, Amen; Rafful, Claudia; Jain, Sonia; Sun, Shelly; Gonzalez-Zuniga, Patricia; Rangel, Gudelia; Strathdee, Steffanie A; Werb, Dan

    2018-02-01

    Although most people who inject drugs (PWID) report receiving assistance during injection initiation events, little research has focused on risk factors among PWID for providing injection initiation assistance. We therefore sought to determine the influence of non-injection drug use among PWID on their risk to initiate others. We used generalized estimating equation (GEE) models on longitudinal data among a prospective cohort of PWID in Tijuana, Mexico (Proyecto El Cuete IV), while controlling for potential confounders. At baseline, 534 participants provided data on injection initiation assistance. Overall, 14% reported ever initiating others, with 4% reporting this behavior recently (i.e., in the past 6 months). In a multivariable GEE model, recent non-injection drug use was independently associated with providing injection initiation assistance (adjusted odds ratio [AOR] = 2.42, 95% confidence interval [CI] = 1.39-4.20). Further, in subanalyses examining specific drug types, recent non-injection use of cocaine (AOR = 9.31, 95% CI = 3.98-21.78), heroin (AOR = 4.00, 95% CI = 1.88-8.54), and methamphetamine (AOR = 2.03, 95% CI = 1.16-3.55) were all significantly associated with reporting providing injection initiation assistance. Our findings may have important implications for the development of interventional approaches to reduce injection initiation and related harms. Further research is needed to validate findings and inform future approaches to preventing entry into drug injecting.

  18. The Cretaceous-Paleogene transition and Chicxulub impact ejecta in the northwestern Gulf of Mexico: Paleoenvironments, sequence stratigraphic setting and target lithologies

    Science.gov (United States)

    Schulte, Peter

    2003-07-01

    The Cretaceous-Paleogene (K-P) transition is characterized by a period of mass extinctions, the Chicxulub impact event, sea-level changes, and considerable climate changes (e.g., cooling). The Gulf of Mexico region is a key area for addressing these issues, specifically because of the proximity to the large Chicxulub impact structure in southern Mexico, and because of its shallow shelf areas throughout the Maastrichtian to Danian period. This study presents the results of a multidisciplinary investigation of Chicxulub impact ejecta and marine sediments from the K-P transition in the western Gulf of Mexico. Sedimentological, mineralogical, and geochemical aspects of K-P sections and cores from northeastern Mexico, Texas, and Alabama have been by studied with focus on Chicxulub ejecta, long- or short-term facies change, and sequence stratigraphic setting. CHICXULUB EJECTA: The Chicxulub ejecta (or impact spherule) deposits from northeastern Mexico and Texas revealed an unexpected complex and localized ejecta composition. Fe-Mg-rich chlorite- as well as Si-Al-K-rich glass-spherules are the predominant silicic ejecta components in northeastern Mexico, whereas in Texas, spherules of Mg-rich smectite compositions were encountered. Spherules contain Fe-Ti-K-rich schlieren, Fe-Mg-rich globules, and rare µm-sized metallic and sulfidic Ni-Co-(Ir-?) rich inclusions. This composition provides evidence for a distinct range of target rocks of mafic to intermediate composition, presumably situated in the northwestern sector of the Chicxulub impact structure, in addition to the possibility of contamination by meteoritic material. The absence of spinels and the ubiquitous presence of hematite and goethite points to high oxygen fugacity during the impact process. Besides these silicic phases, the most prominent ejecta component is carbonate.! Carbonate is found in ejecta deposits as unshocked clasts, accretionary lapilli-like grains, melt globules (often with quenching textures

  19. Modelling initial mortality of Abies religiosa in a crown fire in Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Temiño-Villota, S.; Rodríguez-Trejo, D.A.; Molina Terrén, D.M.; Ryan, K.

    2016-07-01

    Aim of the study: The objectives of this work were to determine which morphological and fire severity variables may help explain the mortality of adult Abies religiosa (Kunth) Schltdl. & Cham., to model the probability of this species after being affected by crown fire, and to obtain more elements to classify the sacred fir in terms of fire resistance. This type of studies are relevant to estimate the impact of crown fires on the climax forests that forms this species. Area of study: The burned forest was located in the southern Mexico City, borough. Material and methods: Morphological variables and fire severity indicators were collected for 335 Abies religiosa trees burned by a mixed severity fire. Logistic regression was used to analyze data and develop models that best explained tree mortality. Main results: Survival was 26.9%. The models for height (p≤0.0001), diameter at breast height (p=0.0082), crown length (p≤0.0001) and crown base height (p≤0.0001) were significant, with a negative relationship between each one of these variables and probability of mortality. The significant severity variables were lethal scorch height (p≤0.0001) and crown kill (p≤ 0.0001), which have a direct relationship with probability of mortality. Highlights: This species is moderately fire-resistant. Crown kill ≥ 70% markedly increases mortality. Silvicultural activities such as pruning, thinning and fuel management can reduce the risk of crown fires. (Author)

  20. Climate Change Community Outreach Initiative (CCCOI)--A Gulf of Mexico Education Partnership

    Science.gov (United States)

    Walker, S. H.; Stone, D.; Schultz, T.; LeBlanc, T.; Miller-Way, T.; Estrada, P.

    2012-12-01

    This five-year, Gulf of Mexico regional collaborative is funded by the National Oceanic and Atmospheric Administration (NOAA)-Office of Education and represents a successful grant submitted by the FL Aquarium as a member of the Association of Zoos and Aquariums (AZA). This climate change effort focuses on enhanced content knowledge and the manner in which personal actions and behaviors contribute to sustainability and stewardship. Diverse audiences—represented by visitors at the informal centers listed above—have been and are involved in the following activities: social networking via responses to climate change surveys; an "ocean and climate change defender" computer game, specifically designed for this project; an average of 10 annual outreach events implemented by these facilities at community festivals; climate change lectures provided to family audiences; and professional development workshops for informal and formal educators. This presentation will provide opportunities and challenges encountered during the first two years of implementation. This regional effort is also aligned with both the Ocean Literacy: Essential Principles and the Climate Literacy: Essential Principles. Additional partners include: Normandeau Associates, Conservation Enterprises, Unlimited, and Mindclay Creative.

  1. Modelling initial mortality of Abies religiosa in a crown fire in Mexico

    Directory of Open Access Journals (Sweden)

    Salomé Temiño-Villota

    2016-04-01

    Full Text Available Aim of study: The objectives of this work were to determine which morphological and fire severity variables may help explain the mortality of adult Abies religiosa (Kunth Schltdl. & Cham., to model the probability of this species after being affected by crown fire, and to obtain more elements to classify the sacred fir in terms of fire resistance. This type of studies are relevant to estimate the impact of crown fires on the climax forests that forms this species.Area of study: The burned forest was located in the southern Mexico City, borough.Material and methods: Morphological variables and fire severity indicators were collected for 335 Abies religiosa trees burned by a mixed severity fire. Logistic regression was used to analyze data and develop models that best explained tree mortality.Main results: Survival was 26.9%. The models for height (p≤0.0001, diameter at breast height (p=0.0082, crown length (p≤0.0001 and crown base height (p≤0.0001 were significant, with a negative relationship between each one of these variables and probability of mortality. The significant severity variables were lethal scorch height (p≤0.0001 and crown kill (p≤ 0.0001, which have a direct relationship with probability of mortality.Highlights: This species is moderately fire-resistant. Crown kill ≥ 70% markedly increases mortality. Silvicultural activities such as pruning, thinning and fuel management can reduce the risk of crown fires.

  2. Spirometry utilisation among Danish adults initiating medication targeting obstructive lung disease

    DEFF Research Database (Denmark)

    Koefoed, Mette

    2015-01-01

    performed. RESULTS: A total of 40,969 adults initiated medication targeting obstructive lung medication in 2008 in Denmark. The mean age of the cohort was 55.6 years (SD18.7) and approximately half of the mediations users had spirometry test performed. Initiating several types of medication targeting......UNLABELLED: This PhD thesis was written during my employment at the Research Unit of General Practice in Odense, University of Southern Denmark. It comprises an overview and three papers, all published or submitted for publication in international peer-reviewed scientific journals. BACKGROUND: Non...... with pharmacotherapy targeting obstructive lung disease and only few have additional tests conducted, although the predictive value of respiratory symptoms for diagnosing obstructive lung disease has proven to be low. Spirometry is recommended as the gold standard for confirming obstructive lung disease, and testing...

  3. Gulf of Mexico Research Initiative Information and Data Cooperative (GRIIDC): Developing a Data Sharing Culture in the Wake of the Deepwater Horizon Oil Spill

    Science.gov (United States)

    Showalter, L. M.; Gibeaut, J. C.

    2016-02-01

    Following the 2010 Deepwater Horizon BP Oil Spill in the Gulf of Mexico, BP committed $500 million (USD) for a research program that investigates the impacts of oil, dispersed oil, and dispersant on the environment and to develop strategies for response to future disasters. This research program, the Gulf of Mexico Research Initiative (GoMRI), is mandated to make all the data produced available to the public. To fulfill this goal, GoMRI developed the Gulf of Mexico Research Initiative Information and Data Cooperative (GRIIDC). GRIIDC is the vehicle by which GoMRI is addressing the data and information needs of this large and varied community of more than 3,000 scientists. The mission of GRIIDC is to ensure a data and information legacy that promotes continual scientific discovery and public awareness of the Gulf of Mexico Ecosystem. As part of its effort to encourage data sharing among scientists interested in oil-spill related research in the Gulf of Mexico GRIIDC provides tools to researchers to facilitate all aspects of the data management process, from developing data management plans, to creating robust metadata records, to ensuring the data is made discoverable by the public. GRIIDC also provides a service to ensure that GoMRI funded publications have any associated data linked and available. This cradle to grave approach to data management has been extremely effective in developing data management practices that will ensure better data stewardship and preservation of all the data created in the GoMRI research program.

  4. Neuroblastoma cell lines contain pluripotent tumor initiating cells that are susceptible to a targeted oncolytic virus.

    Directory of Open Access Journals (Sweden)

    Yonatan Y Mahller

    Full Text Available Although disease remission can frequently be achieved for patients with neuroblastoma, relapse is common. The cancer stem cell theory suggests that rare tumorigenic cells, resistant to conventional therapy, are responsible for relapse. If true for neuroblastoma, improved cure rates may only be achieved via identification and therapeutic targeting of the neuroblastoma tumor initiating cell. Based on cues from normal stem cells, evidence for tumor populating progenitor cells has been found in a variety of cancers.Four of eight human neuroblastoma cell lines formed tumorspheres in neural stem cell media, and all contained some cells that expressed neurogenic stem cell markers including CD133, ABCG2, and nestin. Three lines tested could be induced into multi-lineage differentiation. LA-N-5 spheres were further studied and showed a verapamil-sensitive side population, relative resistance to doxorubicin, and CD133+ cells showed increased sphere formation and tumorigenicity. Oncolytic viruses, engineered to be clinically safe by genetic mutation, are emerging as next generation anticancer therapeutics. Because oncolytic viruses circumvent typical drug-resistance mechanisms, they may represent an effective therapy for chemotherapy-resistant tumor initiating cells. A Nestin-targeted oncolytic herpes simplex virus efficiently replicated within and killed neuroblastoma tumor initiating cells preventing their ability to form tumors in athymic nude mice.These results suggest that human neuroblastoma contains tumor initiating cells that may be effectively targeted by an oncolytic virus.

  5. The use of international service learning initiatives for global health education: case studies from Rwanda and Mexico.

    Science.gov (United States)

    Plumb, Ellen; Roe, Kathleen; Plumb, James; Sepe, Priscilla; Soin, Komal; Ramirez, Aragon; Baganizi, Edmond; Simmons, Rob; Khubchandani, Jagdish

    2013-05-01

    Global health education and health promotion have the potential to engage students, scholars, and practitioners in ways that go beyond the classroom teaching routine. This engagement in global communities, can range from reflection on continuing deep-seated questions about human rights and civic responsibility to the use of health education and promotion-related theoretical, intellectual, and practical skills. In the arena of global health education and promotion, these skills also range from leadership and advocacy to decision making, critical and creative thinking, teamwork, and problem solving. In recent times, there has been a growing interest in cross-cultural collaborations and educational initiatives to improve stakeholder's understanding of global health principles and practices, to enrich the experiences of health professionals, and to improve the lives of those who are disenfranchised and live across borders. In this article of Health Promotion Practice, we highlight two unique cases of cross-national collaborations and provide a glimpse of the various shapes and forms taken by cross-cultural educational initiatives for global health education and promotion. We summarize the history, philosophy, and current working practices relevant to these collaborations, keeping in view the global health domains, competencies, and activities. In addition, we also compare the key components and activities of these two case studies from Rwanda and Mexico, wherein communities in these two countries collaborated with academic institutions and health professionals in the United States.

  6. Terrace Geochemistry at the Shiprock, New Mexico, Disposal Site - WM2017-17232 Initial Phase

    Energy Technology Data Exchange (ETDEWEB)

    Kautsky, Mark [USDOE Office of Legacy Management, Washington, DC (United States); Ranalli, Tony [Navarro Research and Engineering, Oak Ridge, TN (United States); Dander, David [Navarro Research and Engineering, Oak Ridge, TN (United States); Miller, David [Navarro Research and Engineering, Oak Ridge, TN (United States)

    2017-03-08

    The objective of this investigation was to identify and differentiate potential non- mill-related water inputs to a shallow terrace groundwater system through the use of aqueous chemical and isotopic tracers at a former uranium- and vanadium-ore processing facility. Terrace groundwater in the vicinity of the Shiprock, New Mexico, site is hypothesized to be largely anthropogenic because natural rates of recharge in the terrace are likely insufficient to sustain a continuous water table in the terrace alluvial system, as observed in several analogue terrace locations east of the site and in response to post-mill dewatering efforts across the site. The terrace is composed of alluvial sand and gravel and weathered and unweathered Mancos Shale. Terrace groundwater exists and flows in the alluvium and to a much less extent in the Mancos Shale. Historical data established that in both the terrace and floodplain below the terrace, mill-derived uranium and sulfate is found primarily in the alluvium and the upper portion of the weathered Mancos Shale. Groundwater extraction is being conducted in the vicinity of former mill operations and in washes and seeps to dewater the formation and remove contamination, thus eliminating these exposure pathways and minimizing movement to the floodplain. However, past and present contribution of non-mill anthropogenic water sources may be hindering the dewatering effort, resulting in reduced remedy effectiveness. Groundwater source signatures can be determined based on chemical and isotopic ratios and are used to help identify and delineate both mill and non-mill water contributions. Aqueous chemical and isotopic tracers, such as 234U/238U activity ratios and uranium concentrations, δ34S sulfate and sulfate concentrations, tritium concentrations, and δ2Hwater and δ18O water are being used in this Phase I study. The aqueous chemical and isotopic analysis has identified areas on the terrace where groundwater is derived from mill

  7. Estimating the Impact of Earlier ART Initiation and Increased Testing Coverage on HIV Transmission among Men Who Have Sex with Men in Mexico using a Mathematical Model.

    Science.gov (United States)

    Caro-Vega, Yanink; del Rio, Carlos; Lima, Viviane Dias; Lopez-Cervantes, Malaquias; Crabtree-Ramirez, Brenda; Bautista-Arredondo, Sergio; Colchero, M Arantxa; Sierra-Madero, Juan

    2015-01-01

    To estimate the impact of late ART initiation on HIV transmission among men who have sex with men (MSM) in Mexico. An HIV transmission model was built to estimate the number of infections transmitted by HIV-infected men who have sex with men (MSM-HIV+) MSM-HIV+ in the short and long term. Sexual risk behavior data were estimated from a nationwide study of MSM. CD4+ counts at ART initiation from a representative national cohort were used to estimate time since infection. Number of MSM-HIV+ on treatment and suppressed were estimated from surveillance and government reports. Status quo scenario (SQ), and scenarios of early ART initiation and increased HIV testing were modeled. We estimated 14239 new HIV infections per year from MSM-HIV+ in Mexico. In SQ, MSM take an average 7.4 years since infection to initiate treatment with a median CD4+ count of 148 cells/mm3(25th-75th percentiles 52-266). In SQ, 68% of MSM-HIV+ are not aware of their HIV status and transmit 78% of new infections. Increasing the CD4+ count at ART initiation to 350 cells/mm3 shortened the time since infection to 2.8 years. Increasing HIV testing to cover 80% of undiagnosed MSM resulted in a reduction of 70% in new infections in 20 years. Initiating ART at 500 cells/mm3 and increasing HIV testing the reduction would be of 75% in 20 years. A substantial number of new HIV infections in Mexico are transmitted by undiagnosed and untreated MSM-HIV+. An aggressive increase in HIV testing coverage and initiating ART at a CD4 count of 500 cells/mm3 in this population would significantly benefit individuals and decrease the number of new HIV infections in Mexico.

  8. Initiated chemical vapor deposited nanoadhesive for bonding National Ignition Facility's targets

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Tom [Univ. of California, Berkeley, CA (United States)

    2016-05-19

    Currently, the target fabrication scientists in National Ignition Facility Directorate at Lawrence Livermore National Laboratory (LLNL) is studying the propagation force resulted from laser impulses impacting a target. To best study this, they would like the adhesive used to glue the target substrates to be as thin as possible. The main objective of this research project is to create adhesive glue bonds for NIF’s targets that are ≤ 1 μm thick. Polyglycidylmethacrylate (PGMA) thin films were coated on various substrates using initiated chemical vapor deposition (iCVD). Film quality studies using white light interferometry reveal that the iCVD PGMA films were smooth. The coated substrates were bonded at 150 °C under vacuum, with low inflow of Nitrogen. Success in bonding most of NIF’s mock targets at thicknesses ≤ 1 μm indicates that our process is feasible in bonding the real targets. Key parameters that are required for successful bonding were concluded from the bonding results. They include inert bonding atmosphere, sufficient contact between the PGMA films, and smooth substrates. Average bond strength of 0.60 MPa was obtained from mechanical shearing tests. The bonding failure mode of the sheared interfaces was observed to be cohesive. Future work on this project will include reattempt to bond silica aerogel to iCVD PGMA coated substrates, stabilize carbon nanotube forests with iCVD PGMA coating, and kinetics study of PGMA thermal crosslinking.

  9. Targeting cytokine signaling checkpoint CIS activates NK cells to protect from tumor initiation and metastasis

    Science.gov (United States)

    Putz, Eva M.; Guillerey, Camille; Kos, Kevin; Stannard, Kimberley; Miles, Kim; Delconte, Rebecca B.; Nicholson, Sandra E.; Huntington, Nicholas D.; Smyth, Mark J.

    2017-01-01

    ABSTRACT The cytokine-induced SH2-containing protein CIS belongs to the suppressor of cytokine signaling (SOCS) protein family. Here, we show the critical role of CIS in suppressing natural killer (NK) cell control of tumor initiation and metastasis. Cish-deficient mice were highly resistant to methylcholanthrene-induced sarcoma formation and protected from lung metastasis of B16F10 melanoma and RM-1 prostate carcinoma cells. In contrast, the growth of primary subcutaneous tumors, including those expressing the foreign antigen OVA, was unchanged in Cish-deficient mice. The combination of Cish deficiency and relevant targeted and immuno-therapies such as combined BRAF and MEK inhibitors, immune checkpoint blockade antibodies, IL-2 and type I interferon revealed further improved control of metastasis. The data clearly indicate that targeting CIS promotes NK cell antitumor functions and CIS holds great promise as a novel target in NK cell immunotherapy. PMID:28344878

  10. Initial research of np scattering with polarized deuterium target at ANKE/COSY

    Energy Technology Data Exchange (ETDEWEB)

    Gou, Boxing [Institut fuer Kernphysik, Forschungszentrum Juelich, 52425 Juelich (Germany); Institute of Modern Physics, Chinese Academy of Sciences, 73000 Lanzhou (China); Collaboration: ANKE-Collaboration

    2014-07-01

    With the goal of understanding the nuclear forces, the ANKE collaboration has been working on a systematic NN spin program for many years. Due to the lack of free neutron sources experimental data of np scattering are very rare, especially at higher energies. It has been shown that using phase shift analysis (PSA) it is possible to reconstruct np scattering amplitudes from the spin observables of pd → {pp}{sub {sup 1}S{sub 0}}n charge-exchange reaction. So far experiments were conducted using polarized deuteron beams and hydrogen target, which led to valuable results. To extend the research up to the highest nucleon energy available at COSY (2.8 GeV), proton beam and polarized deuterium target will be used. This talk presents the results of the commissioning experiment of a deuterium target at ANKE with emphasis on the initial research of charge-exchange reaction.

  11. INITIAL TEST WELL CONDITIONING AT NOPAL I URANIUM DEPOSIT, SIERRA PENA BLANCA, CHIHUAHUA, MEXICO

    Energy Technology Data Exchange (ETDEWEB)

    R.D. Oliver; J.C. Dinsmoor; S.J. Goldstein; I. Reyes; R. De La Garza

    2005-07-11

    Three test wells, PB-1, PB-2, and PB-3, were drilled at the Nopal I uranium deposit as part of a natural analogue study to evaluate radionuclide transport processes during March-April 2003. The initial pumping to condition the wells was completed during December 2003. The PB-1 well, drilled immediately adjacent to the Nopal I ore body, was continuously cored to a depth of 250 m, terminating 20 m below the top of the measured water level. The PB-2 and PB-3 wells, which were drilled on opposite sides of PB-1 at a radial distance of approximately 40 to 50 m outside of the remaining projected ore body, were also drilled to about 20 m below the top of the measured water level. Each test well was completed with 4-inch (10.2-cm) diameter PVC casing with a slotted liner below the water table. Initial conditioning of all three wells using a submersible pump at low pump rates [less than 1 gallon (3.8 1) per minute] resulted in measurable draw down and recoveries. The greatest drawdown ({approx}15 m) was observed in PB-2, whereas only minor (<1 m) drawdown occurred in PB-3. For PB-1 and PB-2, the water turbidity decreased as the wells were pumped and the pH values decreased, indicating that the contamination from the drilling fluid was reduced as the wells were conditioned. Test wells PB-1 and PB-2 showed increased inflow after several borehole volumes of fluid were removed, but their inflow rates remained less that the pumping rate. Test well PB-3 showed the smallest drawdown and least change in pH and conductivity during initial pumping and quickest recovery with a rise in measured water level after conditioning. The 195 gallons (750 l) of water pumped from PB-3 during conditioning was discharged through a household sponge. That sponge showed measurable gamma radiation, which decayed to background values in less than 12 hours. Preliminary interpretations include filtration of a radioisotope source with a short half-life or of a radioisotope that volatized as the sponge

  12. INITIAL TEST WELL CONDITIONING AT NOPAL I URANIUM DEPOSIT, SIERRA PENA BLANCA, CHIHUAHUA, MEXICO

    International Nuclear Information System (INIS)

    Oliver, R.D.; Dinsmoor, J.C.; Goldstein, S.J.; Reyes, I.; De La Garza, R.

    2005-01-01

    Three test wells, PB-1, PB-2, and PB-3, were drilled at the Nopal I uranium deposit as part of a natural analogue study to evaluate radionuclide transport processes during March-April 2003. The initial pumping to condition the wells was completed during December 2003. The PB-1 well, drilled immediately adjacent to the Nopal I ore body, was continuously cored to a depth of 250 m, terminating 20 m below the top of the measured water level. The PB-2 and PB-3 wells, which were drilled on opposite sides of PB-1 at a radial distance of approximately 40 to 50 m outside of the remaining projected ore body, were also drilled to about 20 m below the top of the measured water level. Each test well was completed with 4-inch (10.2-cm) diameter PVC casing with a slotted liner below the water table. Initial conditioning of all three wells using a submersible pump at low pump rates [less than 1 gallon (3.8 1) per minute] resulted in measurable draw down and recoveries. The greatest drawdown (∼15 m) was observed in PB-2, whereas only minor (<1 m) drawdown occurred in PB-3. For PB-1 and PB-2, the water turbidity decreased as the wells were pumped and the pH values decreased, indicating that the contamination from the drilling fluid was reduced as the wells were conditioned. Test wells PB-1 and PB-2 showed increased inflow after several borehole volumes of fluid were removed, but their inflow rates remained less that the pumping rate. Test well PB-3 showed the smallest drawdown and least change in pH and conductivity during initial pumping and quickest recovery with a rise in measured water level after conditioning. The 195 gallons (750 l) of water pumped from PB-3 during conditioning was discharged through a household sponge. That sponge showed measurable gamma radiation, which decayed to background values in less than 12 hours. Preliminary interpretations include filtration of a radioisotope source with a short half-life or of a radioisotope that volatized as the sponge dried

  13. New Mexico Parks

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset provides an initial version of the locations of parks in New Mexico, in point form, with limited attributes, compiled using available data from a...

  14. New Mexico State Parks

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset provides an initial version of the generalized physical boundaries of New Mexico State Parks, in polygonal form with limited attributes, compiled using...

  15. [How to reduce health inequities by targeting social determinants: the role of the health sector in Mexico].

    Science.gov (United States)

    Martínez Valle, Adolfo; Terrazas, Paulina; Alvarez, Fernando

    2014-04-01

    To study lines of action implemented in Mexico by the health sector from 2007 to 2012 in order to combat health inequities by targeting social determinants. To contribute to better understanding and knowledge of how health system inequalities in the Region of the Americas can be reduced. To formulate recommendations for designing a future public policy agenda to address the social determinants associated with health inequities in Mexico. The policies and programs established in the National Health Program (PRONASA) 2007 - 2012 were reviewed, and those that met four criteria were selected: i) they affected the social determinants of health (SDH); ii) they developed specific lines of action aimed at reducing health inequities; iii) they set concrete goals; and iv) they had been evaluated to determine whether those goals had been met. Three programs were selected: Seguro Popular, Programa de Desarrollo Humano Oportunidades (PDHO), and Caravanas de la Salud. Once each program's specific lines of action targeting SDH had been identified, the monitoring and evaluation indicators established in PRONASA 2007 - 2012, along with other available evaluations and empirical evidence, were used to measure the extent to which the goals were met. The findings showed that Seguro Popular had had a positive impact in terms of the financial protection of lower-income households. Moreover, the reduction in the gap between workers covered by the social security system and those who were not was more evident. By reducing poverty among its beneficiaries, the PDHO also managed to reduce health inequities. The indicators for Caravanas de la Salud, on the other hand, did not show statistically significant differences between the control localities and the localities covered by the program, except in the case of Pap tests. These findings have important public policy implications for designing an agenda that promotes continued targeting of SDH and heightening its impact in terms of reducing

  16. Modifying chemotherapy response by targeted inhibition of eukaryotic initiation factor 4A

    International Nuclear Information System (INIS)

    Cencic, R; Robert, F; Galicia-Vázquez, G; Malina, A; Ravindar, K; Somaiah, R; Pierre, P; Tanaka, J; Deslongchamps, P; Pelletier, J

    2013-01-01

    Translation is regulated predominantly at the initiation phase by several signal transduction pathways that are often usurped in human cancers, including the PI3K/Akt/mTOR axis. mTOR exerts unique administration over translation by regulating assembly of eukaryotic initiation factor (eIF) 4F, a heterotrimeric complex responsible for recruiting 40S ribosomes (and associated factors) to mRNA 5′ cap structures. Hence, there is much interest in targeted therapies that block eIF4F activity to assess the consequences on tumor cell growth and chemotherapy response. We report here that hippuristanol (Hipp), a translation initiation inhibitor that selectively inhibits the eIF4F RNA helicase subunit, eIF4A, resensitizes Eμ-Myc lymphomas to DNA damaging agents, including those that overexpress eIF4E—a modifier of rapamycin responsiveness. As Mcl-1 levels are significantly affected by Hipp, combining its use with the Bcl-2 family inhibitor, ABT-737, leads to a potent synergistic response in triggering cell death in mouse and human lymphoma and leukemia cells. Suppression of eIF4AI using RNA interference also synergized with ABT-737 in murine lymphomas, highlighting eIF4AI as a therapeutic target for modulating tumor cell response to chemotherapy

  17. Activation Kinetics and Off-Target Effects of Thymus-Initiated Cre Transgenes

    Science.gov (United States)

    Shi, Jianjun; Petrie, Howard T.

    2012-01-01

    The bacteriophage enzyme Cre is a site-specific recombinase widely used to delete loxP-flanked DNA sequences in lineage-specific fashion. Several mouse lines that direct Cre expression to lymphoid progenitors in the thymus have been established, but a side-by-side comparison of when they first become active, and/or their relative efficiency at various developmental stages, has been lacking. In this study, we evaluated these in four common Cre transgenic strains with thymus-initiated promoters (Lck, Cd2, or Cd4). We found that while all of them eventually labeled nearly all thymocytes, their kinetics were dramatically different, and other than Cd4[Cre], did not faithfully recapitulate the expression pattern of the corresponding endogenous gene. Perhaps even more importantly, while thymuses from some strains compared favorably to thymuses from control (Cre-negative) mice, we found that Cre expression could also result in off-target effects, including moderate to severe decreases in thymic cellularity. These effects occurred in the absence of loxP-flanked DNA target genes, and were dose and copy number dependent. Loss of cellularity was attributable to a specific decrease in CD4+8+ immature cells, and corresponds to an increased rate of programmed cell death. In addition to a comprehensive analysis of activation kinetics in thymus-initiated Cre transgenes, our data show that Cre is toxic to CD4+8+ cells in a dose-dependent fashion, and emphasize that the choice of thymus-initiated Cre strain is critically important for minimizing off-target effects of Cre. PMID:23049709

  18. Salt Reduction Initiatives around the World - A Systematic Review of Progress towards the Global Target.

    Science.gov (United States)

    Trieu, Kathy; Neal, Bruce; Hawkes, Corinna; Dunford, Elizabeth; Campbell, Norm; Rodriguez-Fernandez, Rodrigo; Legetic, Branka; McLaren, Lindsay; Barberio, Amanda; Webster, Jacqui

    2015-01-01

    To quantify progress with the initiation of salt reduction strategies around the world in the context of the global target to reduce population salt intake by 30% by 2025. A systematic review of the published and grey literature was supplemented by questionnaires sent to country program leaders. Core characteristics of strategies were extracted and categorised according to a pre-defined framework. A total of 75 countries now have a national salt reduction strategy, more than double the number reported in a similar review done in 2010. The majority of programs are multifaceted and include industry engagement to reformulate products (n = 61), establishment of sodium content targets for foods (39), consumer education (71), front-of-pack labelling schemes (31), taxation on high-salt foods (3) and interventions in public institutions (54). Legislative action related to salt reduction such as mandatory targets, front of pack labelling, food procurement policies and taxation have been implemented in 33 countries. 12 countries have reported reductions in population salt intake, 19 reduced salt content in foods and 6 improvements in consumer knowledge, attitudes or behaviours relating to salt. The large and increasing number of countries with salt reduction strategies in place is encouraging although activity remains limited in low- and middle-income regions. The absence of a consistent approach to implementation highlights uncertainty about the elements most important to success. Rigorous evaluation of ongoing programs and initiation of salt reduction programs, particularly in low- and middle- income countries, will be vital to achieving the targeted 30% reduction in salt intake.

  19. Salt Reduction Initiatives around the World - A Systematic Review of Progress towards the Global Target.

    Directory of Open Access Journals (Sweden)

    Kathy Trieu

    Full Text Available To quantify progress with the initiation of salt reduction strategies around the world in the context of the global target to reduce population salt intake by 30% by 2025.A systematic review of the published and grey literature was supplemented by questionnaires sent to country program leaders. Core characteristics of strategies were extracted and categorised according to a pre-defined framework.A total of 75 countries now have a national salt reduction strategy, more than double the number reported in a similar review done in 2010. The majority of programs are multifaceted and include industry engagement to reformulate products (n = 61, establishment of sodium content targets for foods (39, consumer education (71, front-of-pack labelling schemes (31, taxation on high-salt foods (3 and interventions in public institutions (54. Legislative action related to salt reduction such as mandatory targets, front of pack labelling, food procurement policies and taxation have been implemented in 33 countries. 12 countries have reported reductions in population salt intake, 19 reduced salt content in foods and 6 improvements in consumer knowledge, attitudes or behaviours relating to salt.The large and increasing number of countries with salt reduction strategies in place is encouraging although activity remains limited in low- and middle-income regions. The absence of a consistent approach to implementation highlights uncertainty about the elements most important to success. Rigorous evaluation of ongoing programs and initiation of salt reduction programs, particularly in low- and middle- income countries, will be vital to achieving the targeted 30% reduction in salt intake.

  20. Predicting 2D target velocity cannot help 2D motion integration for smooth pursuit initiation.

    Science.gov (United States)

    Montagnini, Anna; Spering, Miriam; Masson, Guillaume S

    2006-12-01

    Smooth pursuit eye movements reflect the temporal dynamics of bidimensional (2D) visual motion integration. When tracking a single, tilted line, initial pursuit direction is biased toward unidimensional (1D) edge motion signals, which are orthogonal to the line orientation. Over 200 ms, tracking direction is slowly corrected to finally match the 2D object motion during steady-state pursuit. We now show that repetition of line orientation and/or motion direction does not eliminate the transient tracking direction error nor change the time course of pursuit correction. Nonetheless, multiple successive presentations of a single orientation/direction condition elicit robust anticipatory pursuit eye movements that always go in the 2D object motion direction not the 1D edge motion direction. These results demonstrate that predictive signals about target motion cannot be used for an efficient integration of ambiguous velocity signals at pursuit initiation.

  1. Targeting the eIF4F translation initiation complex: a critical nexus for cancer development.

    Science.gov (United States)

    Pelletier, Jerry; Graff, Jeremy; Ruggero, Davide; Sonenberg, Nahum

    2015-01-15

    Elevated protein synthesis is an important feature of many cancer cells and often arises as a consequence of increased signaling flux channeled to eukaryotic initiation factor 4F (eIF4F), the key regulator of the mRNA-ribosome recruitment phase of translation initiation. In many cellular and preclinical models of cancer, eIF4F deregulation results in changes in translational efficiency of specific mRNA classes. Importantly, many of these mRNAs code for proteins that potently regulate critical cellular processes, such as cell growth and proliferation, enhanced cell survival and cell migration that ultimately impinge on several hallmarks of cancer, including increased angiogenesis, deregulated growth control, enhanced cellular survival, epithelial-to-mesenchymal transition, invasion, and metastasis. By being positioned as the molecular nexus downstream of key oncogenic signaling pathways (e.g., Ras, PI3K/AKT/TOR, and MYC), eIF4F serves as a direct link between important steps in cancer development and translation initiation. Identification of mRNAs particularly responsive to elevated eIF4F activity that typifies tumorigenesis underscores the critical role of eIF4F in cancer and raises the exciting possibility of developing new-in-class small molecules targeting translation initiation as antineoplastic agents. ©2014 American Association for Cancer Research.

  2. Initial investigations of (np)-scattering with a polarized deuterium target at ANKE-COSY

    Energy Technology Data Exchange (ETDEWEB)

    Gou, Boxing

    2015-07-01

    The understanding of the forces among nucleons is fundamental to the whole of nuclear and hadronic physics. The nucleon-nucleon (NN) scattering is the ideal probe to study the nuclear forces. The scattering amplitudes for the complete description of the NN interactions can be reconstructed from phase-shift analyses (PSA), which requires measurements with polarized experiments. The existing data allow to extract unambiguous proton-proton (pp) amplitudes below 2 GeV. However, there is very little known about the neutron-proton (np) system above 800 MeV nucleon energy. THE ANKE-COSY collaboration has embarked on a systematic program which aims to extract the np scattering amplitudes through the deuteron-proton charge-exchange process dp→{pp}{sub s}n. First part of the program via polarized deuteron beam and hydrogen target allowed successful measurement of np amplitudes up to 1.135 GeV nucleon energy, which is the maximum nucleon energy that can be accessed with deuteron beam at COSY. Via inverse kinematics, i.e. using a proton beam incident on a polarized deuterium target will allow to enhance the np study up to 2.8 GeV, the highest energy available at COSY. The method of inverse kinematics has to be validated prior to the production experiment. As the proof-of-principle (POP) experiment, the initial research has been conducted at proton energy T{sub p}=600 MeV using a polarized deuterium target. The projectiles were measured by two silicon tracking telescopes (STT) placed closed to the target and by the ANKE sub-detection systems. Four polarization modes of the deuterium target were employed. In order to increase the effective target thickness, polarized deuterium atoms produced by the atomic beam source (ABS) was filled into a storage cell, where the circulating COSY beam collides with the target. The target polarizations were measured using the proton-deuteron elastic reaction. The vector and tensor analyzing powers A{sub y} and A{sub yy} of pvector d

  3. Spirometry utilisation among Danish adults initiating medication targeting obstructive lung disease.

    Science.gov (United States)

    Koefoed, Mette Marie

    2015-02-01

    This PhD thesis was written during my employment at the Research Unit of General Practice in Odense, University of Southern Denmark. It comprises an overview and three papers, all published or submitted for publication in international peer-reviewed scientific journals.   Non-infectious dyspnoea, chronic cough and wheezing are common symptoms in the population. Patients often present with these symptoms in general practice and have a high probability of having obstructive lung diseases. However, there is an indication that the majority of these patients are treated empirically with pharmacotherapy targeting obstructive lung disease and only few have additional tests conducted, although the predictive value of respiratory symptoms for diagnosing obstructive lung disease has proven to be low. Spirometry is recommended as the gold standard for confirming obstructive lung disease, and testing can also rule out airway obstruction in patients with respiratory symptoms caused by other illnesses, such as heart failure or lung cancer. Initiating medication for obstructive lung disease without spirometry entails the risk of these patients experiencing unnecessary delay in the diagnostic process and being exposed to unnecessary economic costs and medication risks. The literature has indicated that many users of medication targeting obstructive lung medication have not had spirometry performed and do not actually have obstructive lung disease. This potential quality gap needs to be assessed. Also, in order to target interventions enhancing earlier spirometry utilisation among patients initiating medication targeting obstructive lung disease, improved knowledge on patient and practice factors associated with spirometry testing is needed.   Among first time users of obstructive lung medication we aimed: - To assess to what extent spirometry was performed within the first year of medication use (Study I) - To assess if patient characteristics like socioeconomic and demographic

  4. The antidepressant sertraline inhibits translation initiation by curtailing mammalian target of rapamycin signaling.

    Science.gov (United States)

    Lin, Chen-Ju; Robert, Francis; Sukarieh, Rami; Michnick, Stephen; Pelletier, Jerry

    2010-04-15

    Sertraline, a selective serotonin reuptake inhibitor, is a widely used antidepressant agent. Here, we show that sertraline also exhibits antiproliferative activity. Exposure to sertraline leads to a concentration-dependent decrease in protein synthesis. Moreover, polysome profile analysis of sertraline-treated cells shows a reduction in polysome content and a concomitant increase in 80S ribosomes. The inhibition in translation caused by sertraline is associated with decreased levels of the eukaryotic initiation factor (eIF) 4F complex, altered localization of eIF4E, and increased eIF2alpha phosphorylation. The latter event leads to increased REDD1 expression, which in turn impinges on the mammalian target of rapamycin (mTOR) pathway by affecting TSC1/2 signaling. Sertraline also independently targets the mTOR signaling pathway downstream of Rheb. In the Emu-myc murine lymphoma model where carcinogenesis is driven by phosphatase and tensin homologue (PTEN) inactivation, sertraline is able to enhance chemosensitivity to doxorubicin. Our results indicate that sertraline exerts antiproliferative activity by targeting the mTOR signaling pathway in a REDD1-dependent manner. (c) 2010 AACR.

  5. Targeting the initial investigation and management in cases of acute pulmonary embolism.

    Science.gov (United States)

    Moore, Nicholas; Hawkins, Peter

    2013-01-01

    It was noted by consultants in our hospital that the early investigation of suspected pulmonary embolism (PE) lacked structure. This was causing delays in definitive diagnosis and early management. The resulting unnecessary use of investigation was also wasting resources. In particular, the inappropriate use of serum d-dimer tests was causing concern. The National Institute of Clinical Excellence (NICE) guidelines recommend use of the 2-level Well's score to target investigation in suspected PE. A baseline audit against the NICE guideline revealed that Well's scores were rarely used (only calculated in 12% of cases) and confirmed the suspicion that early investigation was poorly targeted. This project intervened using educational talks promoting the use of Well's scores in cases of suspected PE. Well's score proformas were placed in the emergency department and emergency assessment unit for reference. Their availability was advertised. This significantly increased the use of Well's scores (46% vs 11%, p<0.001). Fewer patients underwent unnecessary d-dimer measurements in cases of likely PE (65% vs 86%). Initial investigation was more targeted in cases where a Well's score had been calculated than in cases without a Well's score. For example, significantly fewer unnecessary d-dimer tests were performed in these cases (45% vs 100%, p<0.05). The cost of unnecessary investigation in suspected PE is not only significant financially but also in the resulting delay in definitive diagnosis and management for the patient. The simple intervention used here was effective in addressing this problem.

  6. PERSPECTIVES OF TEACHER TRAINING AND INITIAL LITERACY IMPLIED IN EDUCATIONAL PROGRAMS OF THE NORMAL SCHOOLS OF MEXICO

    Directory of Open Access Journals (Sweden)

    Efrén Viramontes Anaya

    2013-09-01

    Full Text Available Introduction. The stage or phase of this research project is intended to perform an analysis of approaches for teacher ́s training and early literacy of current language programs in Mexico ́s teacher education. The central con-tent of the document contains the analysis of approaches of teachers ́ trai-ning and initial literacy that lie behind educational programs. The theoretical approach is supported by Pérez Gómez (1996 and in the field of literacy in Ferreiro and Teberobsky (2007 and Lerner (2001. The research methodology is projected into the reconstructive critical pa-radigm as a diagnostic part of a future participative action research that will be conducted in two remaining stages. The perspective of analysis is established by the methodological contributions of Habermas (2008, in the hermeneutic reconstruction of implicit in the analyzed documents approaches. The results and discussion of them that provide lines of analysis of educa-tional programs, the relationship between theory and practice in curriculum approaches and a proposal of teachers profile requirements of language courses for teaching training as well as suggestions for future restructuring of curricula for teacher ́s colleges. In the conclusion, it is established that the perspective and the teacher training approach identified in the curriculum of Primary Education Degree (1997 and 2012 Preschool Education Degree (1999 and 2012 is mainly a model technical decision-making. This explains that the formative processes in teaching students of Tea-chers colleges , there is a tendency to engage in activities that are based on the theory, performing analytical processes that lead to understand the di-dactical principles of approaches for teaching reading instruction and writing, which will be applied in decision-making processes in situ of teaching practi-ce. Initial literacy approaches identified in the curriculum of Elementary and Preschool Degrees 1997 and 1999 plans

  7. Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling

    Directory of Open Access Journals (Sweden)

    Huang Chih-Yang

    2010-10-01

    Full Text Available Abstract Background Head and neck squamous cell carcinoma (HNSCC is a highly lethal cancer that contains cellular and functional heterogeneity. Previously, we enriched a subpopulation of highly tumorigenic head and neck cancer initiating cells (HN-CICs from HNSCC. However, the molecular mechanisms by which to govern the characteristics of HN-CICs remain unclear. GRP78, a stress-inducible endoplasmic reticulum chaperone, has been reported to play a crucial role in the maintenance of embryonic stem cells, but the role of GRP78 in CICs has not been elucidated. Results Initially, we recognized GRP78 as a putative candidate on mediating the stemness and tumorigenic properties of HN-CICs by differential systemic analyses. Subsequently, cells with GRP78 anchored at the plasma membrane (memGRP78+ exerted cancer stemness properties of self-renewal, differentiation and radioresistance. Of note, xenotransplantation assay indicated merely 100 memGRP78+ HNSCCs resulted in tumor growth. Moreover, knockdown of GRP78 significantly reduced the self-renewal ability, side population cells and expression of stemness genes, but inversely promoted cell differentiation and apoptosis in HN-CICs. Targeting GRP78 also lessened tumorigenicity of HN-CICs both in vitro and in vivo. Clinically, co-expression of GRP78 and Nanog predicted the worse survival prognosis of HNSCC patients by immunohistochemical analyses. Finally, depletion of GRP78 in HN-CICs induced the expression of Bax, Caspase 3, and PTEN. Conclusions In summary, memGRP78 should be a novel surface marker for isolation of HN-CICs, and targeting GRP78 signaling might be a potential therapeutic strategy for HNSCC through eliminating HN-CICs.

  8. A Targetable EGFR-Dependent Tumor-Initiating Program in Breast Cancer

    Directory of Open Access Journals (Sweden)

    Paul Savage

    2017-10-01

    Full Text Available Summary: Therapies targeting epidermal growth factor receptor (EGFR have variable and unpredictable responses in breast cancer. Screening triple-negative breast cancer (TNBC patient-derived xenografts (PDXs, we identify a subset responsive to EGFR inhibition by gefitinib, which displays heterogeneous expression of wild-type EGFR. Deep single-cell RNA sequencing of 3,500 cells from an exceptional responder identified subpopulations displaying distinct biological features, where elevated EGFR expression was significantly enriched in a mesenchymal/stem-like cellular cluster. Sorted EGFRhi subpopulations exhibited enhanced stem-like features, including ALDH activity, sphere-forming efficiency, and tumorigenic and metastatic potential. EGFRhi cells gave rise to EGFRhi and EGFRlo cells in primary and metastatic tumors, demonstrating an EGFR-dependent expansion and hierarchical state transition. Similar tumorigenic EGFRhi subpopulations were identified in independent PDXs, where heterogeneous EGFR expression correlated with gefitinib sensitivity. This provides new understanding for an EGFR-dependent hierarchy in TNBC and for patient stratification for therapeutic intervention. : Savage et al. demonstrate that sensitivity to EGFR inhibitor, gefitinib, in triple-negative breast cancer is paradoxically associated with EGFR heterogeneity. Using single-cell RNA sequencing in conjunction with functional assays, they identify TNBC tumors in which EGFR expression identifies cells with tumor-initiating capacity whose proliferative expansion is sensitive to EGFR inhibition. Keywords: breast cancer, tumor heterogeneity, patient-derived xenograft, single-cell RNA sequencing, EGFR inhibition, therapeutic response, tumor-initiating cell, cell hierarchy, BRCA1 mutation

  9. Health initiatives to target obesity in surface transport industries: Review and implications for action

    Directory of Open Access Journals (Sweden)

    Anjum Naweed

    2015-06-01

    Full Text Available Lifestyle-related chronic diseases pose a considerable burden to the individual and the wider society, with correspondingly negative effects on industry. Obesity is a particular problem for the Australasian road and rail industries where it is associated with specific cardiac and fatigue-related safety risks, and levels are higher than those found in the general population. Despite this recognition, and the introduction of National Standards, very little consensus exists regarding approaches to preventative health for surface transport workers. A review of evidence regarding effective health promotion initiatives is urgently needed to inform best practice in this cohort. This review draws together research informing the scope and effectiveness of health promotion programs, initiatives and interventions targeting overweight and obesity in safety critical surface transport domains including the truck, bus and rail industries. A number of health interventions demonstrated measurable successes, including incentivising, peer mentoring, verbal counselling, development of personalised health profiles, and offer of healthier on-site food choices – some of which also resulted in sizeable return on investment over the long term.

  10. Solar Europe industry initiative: research technology development and demonstration in support of 2020 and long-term targets

    NARCIS (Netherlands)

    Sinke, W.C.; Fraile Montoro, D.; Despotou, E.; Nowak, S.; Perezagua, E.

    2010-01-01

    The European Union has set an ambitious target for the implementation of renewable energy technologies by 2020, i.e. a share of 20% of the total energy consumption. In support of these targets the Strategic Energy Technology (SET) Plan has been initiated by the European Commission. One of the key

  11. Increased sensitivity to ionizing radiation by targeting the homologous recombination pathway in glioma initiating cells.

    Science.gov (United States)

    Lim, Yi Chieh; Roberts, Tara L; Day, Bryan W; Stringer, Brett W; Kozlov, Sergei; Fazry, Shazrul; Bruce, Zara C; Ensbey, Kathleen S; Walker, David G; Boyd, Andrew W; Lavin, Martin F

    2014-12-01

    Glioblastoma is deemed the most malignant form of brain tumour, particularly due to its resistance to conventional treatments. A small surviving group of aberrant stem cells termed glioma initiation cells (GICs) that escape surgical debulking are suggested to be the cause of this resistance. Relatively quiescent in nature, GICs are capable of driving tumour recurrence and undergo lineage differentiation. Most importantly, these GICs are resistant to radiotherapy, suggesting that radioresistance contribute to their survival. In a previous study, we demonstrated that GICs had a restricted double strand break (DSB) repair pathway involving predominantly homologous recombination (HR) associated with a lack of functional G1/S checkpoint arrest. This unusual behaviour led to less efficient non-homologous end joining (NHEJ) repair and overall slower DNA DSB repair kinetics. To determine whether specific targeting of the HR pathway with small molecule inhibitors could increase GIC radiosensitivity, we used the Ataxia-telangiectasia mutated inhibitor (ATMi) to ablate HR and the DNA-dependent protein kinase inhibitor (DNA-PKi) to inhibit NHEJ. Pre-treatment with ATMi prior to ionizing radiation (IR) exposure prevented HR-mediated DNA DSB repair as measured by Rad51 foci accumulation. Increased cell death in vitro and improved in vivo animal survival could be observed with combined ATMi and IR treatment. Conversely, DNA-PKi treatment had minimal impact on GICs ability to resolve DNA DSB after IR with only partial reduction in cell survival, confirming the major role of HR. These results provide a mechanistic insight into the predominant form of DNA DSB repair in GICs, which when targeted may be a potential translational approach to increase patient survival. Copyright © 2014. Published by Elsevier B.V.

  12. Where to Go Next? Identifying Target Areas in the North Atlantic for Future Seafloor Mapping Initiatives

    Science.gov (United States)

    Woelfl, A. C.; Jencks, J.; Johnston, G.; Varner, J. D.; Devey, C. W.

    2017-12-01

    Human activities are rapidly expanding into the oceans, yet detailed bathymetric maps do not exist for most of the seafloor that would permit governments to formulate sensible usage rules. Changing this situation will require an enormous international mapping effort. To ensure that this effort is directed towards the regions most in need of mapping, we need to know which areas have already been mapped and which areas are potentially most interesting. Despite various mapping efforts in recent years, large parts of the Atlantic still lack detailed bathymetric information. To successfully plan for future mapping efforts to fill these gaps, knowledge of current data coverage is imperative to avoid duplication of effort. While certain datasets are publically available online (e.g. NOAA's NCEI, EMODnet, IHO-DCDB, LDEO's GMRT), many are not. However, with the limited information we do have at hand, the question remains, where should we map next? And what criteria should we take into account? In 2016, a study was taken on as part of the efforts of the International Atlantic Seabed Mapping Working Group (ASMIWG). The ASMIWG, established by the Tri-Partite Galway Statement Implementation Committee, was tasked to develop a cohesive seabed mapping strategy for the Atlantic Ocean. The aim of our study was to develop a reproducible process for identifying and evaluating potential target areas within the North Atlantic that represent suitable sites for future bathymetric surveys. The sites were selected by applying a GIS-based suitability analysis that included specific user group-based parameters of the marine environment. Furthermore, information regarding current data coverage were gathered to take into account in the selection process. The results reveal the suitability of sites within the North Atlantic based on the selected criteria. Three potential target sites should be seen as flexible suggestions for future mapping initiatives rather than a rigid, defined set of areas

  13. Public health incident management: logistical and operational aspects of the 2009 initial outbreak of H1N1 influenza in Mexico.

    Science.gov (United States)

    Cruz, Miguel A; Hawk, Nicole M; Poulet, Christopher; Rovira, Jose; Rouse, Edward N

    2015-01-01

    Hosting an international outbreak response team can pose a challenge to jurisdictions not familiar with incident management frameworks. Basic principles of team forming, organizing, and executing mission critical activities require simple and flexible communication that can be easily understood by the host country's public health leadership and international support agencies. Familiarity with incident command system principles before a public health emergency could save time and effort during the initial phases of the response and aid in operationalizing and sustaining complex field activities throughout the response. The 2009 initial outbreak of H1N1 in Mexico highlighted the importance of adequately organizing and managing limited resources and expertise using incident management principles. This case study describes logistical and operational aspects of the response and highlights challenges faced during this response that may be relevant to the organization of public health responses and incidents requiring international assistance and cooperation.

  14. Using Deep Learning for Targeted Data Selection, Improving Satellite Observation Utilization for Model Initialization

    Science.gov (United States)

    Lee, Y. J.; Bonfanti, C. E.; Trailovic, L.; Etherton, B.; Govett, M.; Stewart, J.

    2017-12-01

    At present, a fraction of all satellite observations are ultimately used for model assimilation. The satellite data assimilation process is computationally expensive and data are often reduced in resolution to allow timely incorporation into the forecast. This problem is only exacerbated by the recent launch of Geostationary Operational Environmental Satellite (GOES)-16 satellite and future satellites providing several order of magnitude increase in data volume. At the NOAA Earth System Research Laboratory (ESRL) we are researching the use of machine learning the improve the initial selection of satellite data to be used in the model assimilation process. In particular, we are investigating the use of deep learning. Deep learning is being applied to many image processing and computer vision problems with great success. Through our research, we are using convolutional neural network to find and mark regions of interest (ROI) to lead to intelligent extraction of observations from satellite observation systems. These targeted observations will be used to improve the quality of data selected for model assimilation and ultimately improve the impact of satellite data on weather forecasts. Our preliminary efforts to identify the ROI's are focused in two areas: applying and comparing state-of-art convolutional neural network models using the analysis data from the National Center for Environmental Prediction (NCEP) Global Forecast System (GFS) weather model, and using these results as a starting point to optimize convolution neural network model for pattern recognition on the higher resolution water vapor data from GOES-WEST and other satellite. This presentation will provide an introduction to our convolutional neural network model to identify and process these ROI's, along with the challenges of data preparation, training the model, and parameter optimization.

  15. First confirmation and characterization of target and non-target site resistance to glyphosate in Palmer amaranth (Amaranthus palmeri) from Mexico.

    Science.gov (United States)

    Dominguez-Valenzuela, Jose Alfredo; Gherekhloo, Javid; Fernández-Moreno, Pablo Tomás; Cruz-Hipolito, Hugo Enrique; Alcántara-de la Cruz, Ricardo; Sánchez-González, Eduardo; De Prado, Rafael

    2017-06-01

    Following the introduction of glyphosate-resistant (GR)-cotton crops in Mexico, farmers have relied upon glyphosate as being the only herbicide for in-season weed control. Continuous use of glyphosate within the same year and over multiple successive years has resulted in the selection of glyphosate resistance in Palmer amaranth (Amarantus palmeri). Dose-response assays confirmed resistance in seven different accessions. The resistance ratio based on GR 50 values (50% growth reduction) varied between 12 and 83. At 1000 μM glyphosate, shikimic acid accumulation in the S-accession was 30- to 2-fold higher at compared to R-accessions. At 96 h after treatment, 35-44% and 61% of applied 14 C-glyphosate was taken up by leaves of plants from R- and S-accessions, respectively. At this time, a significantly higher proportion of the glyphosate absorbed remained in the treated leaf of R-plants (55-69%) compared to S-plants (36%). Glyphosate metabolism was low and did not differ between resistant and susceptible plants. Glyphosate was differentially metabolized to AMPA and glyoxylate in plants of R- and S-accessions, although it was low in both accessions (glyphosate collected from GR-cotton crops from Mexico. This is the first study demonstrating glyphosate-resistance in Palmer amaranth from Mexico. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  16. Initial thermal state of the Los Humeros, Puebla, Mexico, geothermal field; Estado termico inicial del campo geotermico de Los Humeros, Puebla, Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Garcia Gutierrez, Alfonso [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico)]. E-mail: aggarcia@iie.org.mx

    2009-01-15

    The initial temperatures field is presented for 40 wells in the Los Humeros geothermal reservoir, along with an elevation curve based on the formation temperature or the most probable reservoir temperature. Stabilized temperatures were estimated using the Radial Spherical Heat Flow method, chosen over the Horner method based on the numerical simulation of the circulation and stop processes of well H-26. In this well, the last temperature log series was reproduced, considering circulation losses. The temperatures were used to produce isothermal curves over three geological sections of the field, which represent the initial distribution of temperatures in the reservoir and show the thermal characteristics and the relationships among thermal anomalies and faults in the reservoir. The elevation curve plotted against the initial temperature of the formation was generated based on detection of the main feed zones at each well, which in turn was developed using detailed analyses of diverse information, such as temperature logs, circulation losses, lithology, well completion, and heat velocities. Based on the results, two groups of wells may be distinguished: one between 1000 and 1600 masl with temperatures from 290 to 330 degrees Celsius, and one between 900 and 0 masl with temperatures from 300 to 400 degrees Celsius. [Spanish] En este trabajo se presenta el campo de temperatura inicial del yacimiento geotermico de Los Humeros y una curva de elevacion contra la temperatura de formacion o temperatura mas probable del yacimiento, obtenida para 40 pozos del campo. Las temperaturas estabilizadas se estimaron mediante el metodo de Flujo de Calor Esferico Radial, y su eleccion sobre las temperaturas del metodo de Horner se soporta con simulacion numerica de los procesos de circulacion y paro del pozo H-26, en la cual la ultima serie de registros se reprodujo considerando perdidas de circulacion. Con estas temperaturas se generaron curvas isotermicas para tres secciones

  17. Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner

    Czech Academy of Sciences Publication Activity Database

    Yan, B.; Stantic, M.; Zobalová, Renata; Bezawork-Geleta, A.; Stapelberg, M.; Stursa, J.; Prokopová, Kateřina; Dong, L.; Neužil, Jiří

    2015-01-01

    Roč. 15, č. 401 (2015) ISSN 1471-2407 R&D Projects: GA MZd NT14078; GA MŠk(CZ) ED1.1.00/02.0109 Institutional support: RVO:86652036 Keywords : Tumour-initiating cells * Mitochondrially targeted vitamin E succinate * Complex II Subject RIV: FD - Oncology ; Hematology Impact factor: 3.265, year: 2015

  18. Lack of spirometry use in Danish patients initiating medication targeting obstructive lung disease

    DEFF Research Database (Denmark)

    Koefoed, Mette; Christensen, René Depont; Søndergaard, Jens

    2012-01-01

    Research indicates that a large proportion of patients using medication targeting obstructive lung disease have no history of spirometry testing.......Research indicates that a large proportion of patients using medication targeting obstructive lung disease have no history of spirometry testing....

  19. Influence of socioeconomic and demographic status on spirometry testing in patients initiating medication targeting obstructive lung disease

    DEFF Research Database (Denmark)

    Koefoed, Mette M; Søndergaard, Jens; Christensen, René Depont

    2013-01-01

    a possible association between education, income, labour market affiliation, cohabitation status and having spirometry performed when initiating medication targeting obstructive pulmonary disease. METHODS: We conducted a population-based cohort study. Danish national registers were linked, retrieving data...... on prescriptions, spirometry testing, socioeconomic and demographic variables in all first time users of medication targeting obstructive lung disease in 2008. RESULTS: A total of 37,734 persons were included and approximately half of the cohort had spirometry performed. Among medication users under 65 years...... spirometry performed among men (OR = 0.78, CI = 0.69-0.88). CONCLUSION: Social inequity in spirometry testing among patients initiating medication targeting obstructive lung disease was confirmed in this study. Increased focus on spirometry testing among elderly men living alone, among the unemployed...

  20. Initial evaluations of a Gulf of Mexico/Caribbean ocean forecast system in the context of the Deepwater Horizon disaster

    Science.gov (United States)

    Zaron, Edward D.; Fitzpatrick, Patrick J.; Cross, Scott L.; Harding, John M.; Bub, Frank L.; Wiggert, Jerry D.; Ko, Dong S.; Lau, Yee; Woodard, Katharine; Mooers, Christopher N. K.

    2015-12-01

    In response to the Deepwater Horizon (DwH) oil spill event in 2010, the Naval Oceanographic Office deployed a nowcast-forecast system covering the Gulf of Mexico and adjacent Caribbean Sea that was designated Americas Seas, or AMSEAS, which is documented in this manuscript. The DwH disaster provided a challenge to the application of available ocean-forecast capabilities, and also generated a historically large observational dataset. AMSEAS was evaluated by four complementary efforts, each with somewhat different aims and approaches: a university research consortium within an Integrated Ocean Observing System (IOOS) testbed; a petroleum industry consortium, the Gulf of Mexico 3-D Operational Ocean Forecast System Pilot Prediction Project (GOMEX-PPP); a British Petroleum (BP) funded project at the Northern Gulf Institute in response to the oil spill; and the Navy itself. Validation metrics are presented in these different projects for water temperature and salinity profiles, sea surface wind, sea surface temperature, sea surface height, and volume transport, for different forecast time scales. The validation found certain geographic and time biases/errors, and small but systematic improvements relative to earlier regional and global modeling efforts. On the basis of these positive AMSEAS validation studies, an oil spill transport simulation was conducted using archived AMSEAS nowcasts to examine transport into the estuaries east of the Mississippi River. This effort captured the influences of Hurricane Alex and a non-tropical cyclone off the Louisiana coast, both of which pushed oil into the western Mississippi Sound, illustrating the importance of the atmospheric influence on oil spills such as DwH.

  1. Setting ART initiation targets in response to changing guidelines: The importance of addressing both steady-state and backlog.

    Science.gov (United States)

    Martin, Catherine; Naidoo, Nicolette P; Venter, W D Francois; Jaffer, Ambereen; Barker, Pierre M

    2014-05-12

    Target setting is useful in planning, assessing and improving antiretroviral treatment (ART) programmes. In the past 4 years, the ART initiation environment has been transformed due to the change in eligibility criteria (starting ART at a CD4+ count ART. To describe and illustrate the use of a target-setting model for estimating district-based targets in the era of an expanding ART programme and changing CD4+ count thresholds for ART initiation. Using previously described models and data for annual new HIV infections, we estimated both steady-state need for ART initiation and backlog in a North West Province district, accounting for the shift in eligibility. Comparison of actual v. targeted ART initiations was undertaken. The change in CD4+ count threshold adds a once-off group of newly eligible patients to the pool requiring ART - the backlog. The steady-state remains unchanged as it is determined by the annual rate of new HIV infections in previous years. The steady-state need for the district was 639 initiations/month, and the backlog was ~15,388 patients. After the shift in eligibility in September 2011, the steady-state target was exceeded over several months with some backlog addressed. Of the total backlog for this district, 72% remains to be cleared. South Africa has two pools of patients who need ART: the steady-state of HIV-infected patients entering the programme each year, determined by historical infection rates; and the backlog created by the shift in eligibility. The healthcare system needs to build long- term capacity to meet the steady-state need for ART and additional capacity to address the backlog.

  2. HIV-1 reverse transcription initiation: a potential target for novel antivirals?

    NARCIS (Netherlands)

    Abbink, Truus E. M.; Berkhout, Ben

    2008-01-01

    Reverse transcription is an essential step in the retroviral life cycle, as it converts the genomic RNA into DNA. In this review, we describe recent developments concerning the initiation step of this complex, multi-step reaction. During initiation of reverse transcription, a cellular tRNA primer is

  3. The Nike KrF laser facility: Performance and initial target experiments

    Science.gov (United States)

    Obenschain, S. P.; Bodner, S. E.; Colombant, D.; Gerber, K.; Lehmberg, R. H.; McLean, E. A.; Mostovych, A. N.; Pronko, M. S.; Pawley, C. J.; Schmitt, A. J.; Sethian, J. D.; Serlin, V.; Stamper, J. A.; Sullivan, C. A.; Dahlburg, J. P.; Gardner, J. H.; Chan, Y.; Deniz, A. V.; Hardgrove, J.; Lehecka, T.; Klapisch, M.

    1996-05-01

    Krypton-fluoride (KrF) lasers are of interest to laser fusion because they have both the large bandwidth capability (≳THz) desired for rapid beam smoothing and the short laser wavelength (1/4 μm) needed for good laser-target coupling. Nike is a recently completed 56-beam KrF laser and target facility at the Naval Research Laboratory. Because of its bandwidth of 1 THz FWHM (full width at half-maximum), Nike produces more uniform focal distributions than any other high-energy ultraviolet laser. Nike was designed to study the hydrodynamic instability of ablatively accelerated planar targets. First results show that Nike has spatially uniform ablation pressures (Δp/pNike laser in producing uniform illumination, and its performance in correspondingly uniform acceleration of targets.

  4. Initial Pressure Distribution in the Geothermal Field of Los Humeros, Puebla, Mexico; Distribucion de presion inicial en el campo geotermico de Los Humeros, Puebla, Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Arellano, Victor M.; Izquierdo, Georgina; Aragon, Alfonso; Barragan, Rosa Maria; Garcia, Alfonso [Instituto de Investigaciones Electricas (Mexico); Pizano, Arturo [Comision Federal de Electricidad (Mexico)

    2001-09-01

    To obtain the undisturbed distribution of pressures of a field flow, a significant amount of data concerning geological, geochemical, geophysical, and field drilling and engineering aspects, from 42 wells located at the geothermal field of Los Humeros, was analysed. Based on the studied data, models of the field pressure distribution in its initial state were developed. The models reveal the existence of at least two deposits. One of them, the most superficial, is located between 1025 and 1600 meters over the sea level, and from its excellent congruence with the pressure profile of a boiling water column, it may be considered as a predominantly liquid field. The pressure profile of this field is that of a boiling water column, at a temperature of about 300-330 Celsius degrees. The second field is below 850 meters over the sea level and from the known data it reaches at least 100 meters over the sea level. It is considered a low-liquid saturated field. The temperatures of the wells supplied by this field were estimated to be about 300-40 Celsius degrees. [Spanish] Para inferir las distribuciones de presion no perturbadas del fluido del yacimiento, se analizo una considerable cantidad de informacion relacionada con los aspectos geologicos, geoquimicos, geofisicos, de perforacion e ingenieria de yacimientos, correspondiente a 42 pozos del camo geotermico de Los Humeros, Puebla. Sobre la base de los datos analizados se desarrollaron modelos de distribucion de la presion del yacimiento en su estado inicial. Dichos modelos revelan la existencia de, cuando menos, dos yacimientos. El primero y mas superficial se encuentra localizado entre 1,600 y 1,025 metros sobre el nivel del mar (msnm), y dada su excelente concordancia con el perfil de presion correspondiente a una columna de agua en ebullicion, puede afirmarse que se trata de un yacimiento de liquido dominante. El perfil de presion de este yacimiento corresponde a una columna de agua en ebullicion de 300 a 330

  5. The Nike KrF laser facility: Performance and initial target experiments

    International Nuclear Information System (INIS)

    Obenschain, S.P.; Bodner, S.E.; Colombant, D.; Gerber, K.; Lehmberg, R.H.; McLean, E.A.; Mostovych, A.N.; Pronko, M.S.; Pawley, C.J.; Schmitt, A.J.; Sethian, J.D.; Serlin, V.; Stamper, J.A.; Sullivan, C.A.; Dahlburg, J.P.; Gardner, J.H.; Chan, Y.; Deniz, A.V.; Hardgrove, J.; Lehecka, T.; Klapisch, M.

    1996-01-01

    Krypton-fluoride (KrF) lasers are of interest to laser fusion because they have both the large bandwidth capability (approx-gt THz) desired for rapid beam smoothing and the short laser wavelength (1/4 μm) needed for good laser endash target coupling. Nike is a recently completed 56-beam KrF laser and target facility at the Naval Research Laboratory. Because of its bandwidth of 1 THz FWHM (full width at half-maximum), Nike produces more uniform focal distributions than any other high-energy ultraviolet laser. Nike was designed to study the hydrodynamic instability of ablatively accelerated planar targets. First results show that Nike has spatially uniform ablation pressures (Δp/p<2%). Targets have been accelerated for distances sufficient to study hydrodynamic instability while maintaining good planarity. In this review we present the performance of the Nike laser in producing uniform illumination, and its performance in correspondingly uniform acceleration of targets. copyright 1996 American Institute of Physics

  6. Tumor initiating cells and chemoresistance: which is the best strategy to target colon cancer stem cells?

    Science.gov (United States)

    Paldino, Emanuela; Tesori, Valentina; Casalbore, Patrizia; Gasbarrini, Antonio; Puglisi, Maria Ausiliatrice

    2014-01-01

    There is an emerging body of evidence that chemoresistance and minimal residual disease result from selective resistance of a cell subpopulation from the original tumor that is molecularly and phenotypically distinct. These cells are called "cancer stem cells" (CSCs). In this review, we analyze the potential targeting strategies for eradicating CSCs specifically in order to develop more effective therapeutic strategies for metastatic colon cancer. These include induction of terminal epithelial differentiation of CSCs or targeting some genes expressed only in CSCs and involved in self-renewal and chemoresistance. Ideal targets could be cell regulators that simultaneously control the stemness and the resistance of CSCs. Another important aspect of cancer biology, which can also be harnessed to create novel broad-spectrum anticancer agents, is the Warburg effect, also known as aerobic glycolysis. Actually, little is yet known with regard to the metabolism of CSCs population, leaving an exciting unstudied avenue in the dawn of the emerging field of metabolomics.

  7. 76 FR 33218 - Carbon and Certain Alloy Steel Wire Rod From Mexico: Initiation of Anti-Circumvention Inquiry of...

    Science.gov (United States)

    2011-06-08

    ... ArcelorMittal USA, et al.) and Nucor Corporation and Cascade Steel Rolling Mills, Inc. (collectively, Nucor/Cascade) requested that the Department of Commerce (the Department) initiate a scope inquiry...

  8. Perspectives on the Cultural Appropriacy of Hong Kong's Target-Oriented Curriculum (TOC) Initiative.

    Science.gov (United States)

    Carless, David Robert

    1999-01-01

    Explores the impact of Chinese culture on the school curriculum in Hong Kong. Argues that the Target-Oriented Curriculum (TOC) transplanted from western-based concepts is not commensurate with the local Chinese cultural context, and therefore leads to many problems when being implemented in schools. (Author/VWL)

  9. Workplace bullying as sensemaking: An analysis of target and actor perspectives on initial hostile interactions

    Czech Academy of Sciences Publication Activity Database

    Zábrodská, Kateřina; Ellwood, C.; Zaemdaar, S.; Mudrák, Jiří

    2016-01-01

    Roč. 22, č. 2 (2016), s. 136-157 ISSN 1475-9551 R&D Projects: GA ČR GPP407/10/P146; GA ČR GA14-02098S Institutional support: RVO:68081740 Keywords : workplace bullying * workplace hostility * sensemaking * target * actor * collective biography * stories Subject RIV: AN - Psychology Impact factor: 0.489, year: 2016

  10. Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner

    International Nuclear Information System (INIS)

    Yan, Bing; Stantic, Marina; Zobalova, Renata; Bezawork-Geleta, Ayenachew; Stapelberg, Michael; Stursa, Jan; Prokopova, Katerina; Dong, Lanfeng; Neuzil, Jiri

    2015-01-01

    Accumulating evidence suggests that breast cancer involves tumour-initiating cells (TICs), which play a role in initiation, metastasis, therapeutic resistance and relapse of the disease. Emerging drugs that target TICs are becoming a focus of contemporary research. Mitocans, a group of compounds that induce apoptosis of cancer cells by destabilising their mitochondria, are showing their potential in killing TICs. In this project, we investigated mitochondrially targeted vitamin E succinate (MitoVES), a recently developed mitocan, for its in vitro and in vivo efficacy against TICs. The mammosphere model of breast TICs was established by culturing murine NeuTL and human MCF7 cells as spheres. This model was verified by stem cell marker expression, tumour initiation capacity and chemotherapeutic resistance. Cell susceptibility to MitoVES was assessed and the cell death pathway investigated. In vivo efficacy was studied by grafting NeuTL TICs to form syngeneic tumours. Mammospheres derived from NeuTL and MCF7 breast cancer cells were enriched in the level of stemness, and the sphere cells featured altered mitochondrial function. Sphere cultures were resistant to several established anti-cancer agents while they were susceptible to MitoVES. Killing of mammospheres was suppressed when the mitochondrial complex II, the molecular target of MitoVES, was knocked down. Importantly, MitoVES inhibited progression of syngeneic HER2 high tumours derived from breast TICs by inducing apoptosis in tumour cells. These results demonstrate that using mammospheres, a plausible model for studying TICs, drugs that target mitochondria efficiently kill breast tumour-initiating cells. The online version of this article (doi:10.1186/s12885-015-1394-7) contains supplementary material, which is available to authorized users

  11. Initial Time Of Two High Altitude Crater Lakes (Nevado De Toluca, Central Mexico Recorded In Subfossil Cladocera

    Directory of Open Access Journals (Sweden)

    Szeroczyńska Krystyna

    2015-12-01

    Full Text Available The objective of this study was the recognition and reconstruction of the origin of two high altitude lakes and the ecological conditions of their early existence based on subfossil Cladocera and chemical analyses. The study focused on the oldest lacustrine sediments from Lake Sol and Lake Luna, located in the crater of Volcano Nevado de Toluca (Central Mexico. The Nevado de Toluca crater developed approximately 12 ka yr BP. According to the literature, the volcano was last active approximately 3.3 ka yr BP, and the lakes developed after that eruption. The remains of nine Cladocera species were found in the bottom sediments of both lakes. The most dominant taxa were two endemic littoral species: Alona manueli and Iliocryptus nevadensis. The total frequency of Cladocera specimens in both of the sediment cores was very low. No Cladocera remains were recorded in the sediment layer at depths between 123–103 m from Lake Luna. The results of the lithological and geochemical analyses showed that this sediment layer was composed of allochthonous material, probably originating from slid down from the volcanic cone. This was suggested by the content of silica (up to 13%, iron (up to 12%, and titanium (up to 4%. The Cladocera remains recorded in the bottom sediments suggested that both reservoirs developed as freshwater lakes at the beginning of the sedimentation. The calibrated radiocarbon dates obtained for the bottom samples were 4040 to 3990 yr BP for Lake Luna (129 cm and 4485 to 4485 yr BP for Lake Sol (89 cm. The obtained ages were older than the dates of the last eruption, which occurred approximately 3300 yr BP. This result was likely related to the type of radiocarbon dated materials (charcoals.

  12. Detection of Traffic Initiated by Mobile Malware Targeting Android Devices in 3GPP Networks

    OpenAIRE

    Kühnel, Marián

    2017-01-01

    Android devices have become the most popular of mobile devices; omnipresent in both business and private use. They are virtually always on and offer functionalities exceeding those of desktop computers. These properties, as well as sensitive information stored on Android devices, render them an attractive target for mobile malware authors. As the volume of mobile malware increases, analysis is becoming challenging and, sometimes, infeasible. Additionally, current network-based intrusion detec...

  13. Rapid Automated Target Segmentation and Tracking on 4D Data without Initial Contours

    International Nuclear Information System (INIS)

    Chebrolu, V.V.; Chebrolu, V.V.; Saenz, D.; Tewatia, D.; Paliwal, B.R.; Chebrolu, V.V.; Saenz, D.; Paliwal, B.R.; Sethares, W.A.; Cannon, G.

    2014-01-01

    To achieve rapid automated delineation of gross target volume (GTV) and to quantify changes in volume/position of the target for radiotherapy planning using four-dimensional (4D) CT. Methods and Materials. Novel morphological processing and successive localization (MPSL) algorithms were designed and implemented for achieving auto segmentation. Contours automatically generated using MPSL method were compared with contours generated using state-of-the-art deformable registration methods (using Elastix © and MIMV ista software). Metrics such as the Dice similarity coefficient, sensitivity, and positive predictive value (PPV) were analyzed. The target motion tracked using the centroid of the GTV estimated using MPSL method was compared with motion tracked using deformable registration methods. Results. MPSL algorithm segmented the GTV in 4DCT images in 27.0 ±11.1 seconds per phase ( 512 ×512 resolution) as compared to 142.3±11.3 seconds per phase for deformable registration based methods in 9 cases. Dice coefficients between MPSL generated GTV contours and manual contours (considered as ground-truth) were 0.865 ± 0.037. In comparison, the Dice coefficients between ground-truth and contours generated using deformable registration based methods were 0.909 ± 0.051. Conclusions. The MPSL method achieved similar segmentation accuracy as compared to state-of-the-art deformable registration based segmentation methods, but with significant reduction in time required for GTV segmentation.

  14. Tumor Initiating Cells and Chemoresistance: Which Is the Best Strategy to Target Colon Cancer Stem Cells?

    Directory of Open Access Journals (Sweden)

    Emanuela Paldino

    2014-01-01

    Full Text Available There is an emerging body of evidence that chemoresistance and minimal residual disease result from selective resistance of a cell subpopulation from the original tumor that is molecularly and phenotypically distinct. These cells are called “cancer stem cells” (CSCs. In this review, we analyze the potential targeting strategies for eradicating CSCs specifically in order to develop more effective therapeutic strategies for metastatic colon cancer. These include induction of terminal epithelial differentiation of CSCs or targeting some genes expressed only in CSCs and involved in self-renewal and chemoresistance. Ideal targets could be cell regulators that simultaneously control the stemness and the resistance of CSCs. Another important aspect of cancer biology, which can also be harnessed to create novel broad-spectrum anticancer agents, is the Warburg effect, also known as aerobic glycolysis. Actually, little is yet known with regard to the metabolism of CSCs population, leaving an exciting unstudied avenue in the dawn of the emerging field of metabolomics.

  15. Rapid Automated Target Segmentation and Tracking on 4D Data without Initial Contours

    Directory of Open Access Journals (Sweden)

    Venkata V. Chebrolu

    2014-01-01

    Full Text Available Purpose. To achieve rapid automated delineation of gross target volume (GTV and to quantify changes in volume/position of the target for radiotherapy planning using four-dimensional (4D CT. Methods and Materials. Novel morphological processing and successive localization (MPSL algorithms were designed and implemented for achieving autosegmentation. Contours automatically generated using MPSL method were compared with contours generated using state-of-the-art deformable registration methods (using Elastix© and MIMVista software. Metrics such as the Dice similarity coefficient, sensitivity, and positive predictive value (PPV were analyzed. The target motion tracked using the centroid of the GTV estimated using MPSL method was compared with motion tracked using deformable registration methods. Results. MPSL algorithm segmented the GTV in 4DCT images in 27.0±11.1 seconds per phase (512×512 resolution as compared to 142.3±11.3 seconds per phase for deformable registration based methods in 9 cases. Dice coefficients between MPSL generated GTV contours and manual contours (considered as ground-truth were 0.865±0.037. In comparison, the Dice coefficients between ground-truth and contours generated using deformable registration based methods were 0.909 ± 0.051. Conclusions. The MPSL method achieved similar segmentation accuracy as compared to state-of-the-art deformable registration based segmentation methods, but with significant reduction in time required for GTV segmentation.

  16. Rapid Automated Target Segmentation and Tracking on 4D Data without Initial Contours.

    Science.gov (United States)

    Chebrolu, Venkata V; Saenz, Daniel; Tewatia, Dinesh; Sethares, William A; Cannon, George; Paliwal, Bhudatt R

    2014-01-01

    Purpose. To achieve rapid automated delineation of gross target volume (GTV) and to quantify changes in volume/position of the target for radiotherapy planning using four-dimensional (4D) CT. Methods and Materials. Novel morphological processing and successive localization (MPSL) algorithms were designed and implemented for achieving autosegmentation. Contours automatically generated using MPSL method were compared with contours generated using state-of-the-art deformable registration methods (using Elastix© and MIMVista software). Metrics such as the Dice similarity coefficient, sensitivity, and positive predictive value (PPV) were analyzed. The target motion tracked using the centroid of the GTV estimated using MPSL method was compared with motion tracked using deformable registration methods. Results. MPSL algorithm segmented the GTV in 4DCT images in 27.0 ± 11.1 seconds per phase (512 × 512 resolution) as compared to 142.3 ± 11.3 seconds per phase for deformable registration based methods in 9 cases. Dice coefficients between MPSL generated GTV contours and manual contours (considered as ground-truth) were 0.865 ± 0.037. In comparison, the Dice coefficients between ground-truth and contours generated using deformable registration based methods were 0.909 ± 0.051. Conclusions. The MPSL method achieved similar segmentation accuracy as compared to state-of-the-art deformable registration based segmentation methods, but with significant reduction in time required for GTV segmentation.

  17. 77 FR 4007 - Large Residential Washers From the Republic of Korea and Mexico: Initiation of Antidumping Duty...

    Science.gov (United States)

    2012-01-26

    ... washing machines. The petitioner relied on the FY 2010 consolidated financial statements of the same two... consolidated financial statements of the Mexican producer's parent company. See Mexican Initiation Checklist... CV to reflect the financial expenses based on the FY 2010 consolidated financial statements of the...

  18. Targets for Marine Corps Purchasing and Supply Management Initiatives: Spend Analysis Findings

    Science.gov (United States)

    2011-01-01

    Corps Purchasing and Supply Management Initiatives: Spend Analysis Findings source contracts with providers in them. We also examine contract “ churn ...repair, and rebuilding of equipment; general purpose ADP equipment; ADP and telecommunication ser- vices—are also shown in the previous chart for top...to $469 million in FY 2004. The spend for other ADP and telecommunication services, $264 million in FY 2004, was not even in the top ten in FY 2003

  19. The global threat reduction initiative and conversion of isotope production to LEU targets

    International Nuclear Information System (INIS)

    Kuperman, A. J.

    2005-01-01

    The U.S. Global Threat Reduction Initiative (GTRI) has given a decisive impetus to the RERTR program's longstanding goal of converting worldwide production of medical radioisotopes from reliance on bomb-grade, highly enriched uranium (HEU) to low-enriched uranium (LEU) unsuitable for weapons. Although the four major; isotope producers continue to resist calls for conversion, they face mounting pressure from a variety of fronts including: (1) GTRI; (2) a related, multilateral U.S. initiative to forge agreement on conversion among the states that are home to the major producers; (3) an IAEA effort to provide technical assistance that will facilitate large-scale production of medical isotopes using LEU by producers who seek to do so; (4) planned production in the United States of substantial quantities of medical isotopes using LEU; and (5) pending U.S. legislation that would prohibit the export of HEU for production of isotopes as soon as alternative, LEU-produced isotopes are available. Accordingly, it now appears inevitable that worldwide isotope production will be converted from reliance on HEU to LEU. The only remaining question is which producers will be the first to reliably deliver sizeable quantities of LEU-produced isotopes and thereby capture global market share from the others. (author)

  20. A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor.

    Science.gov (United States)

    Gadd, Samantha; Huff, Vicki; Walz, Amy L; Ooms, Ariadne H A G; Armstrong, Amy E; Gerhard, Daniela S; Smith, Malcolm A; Auvil, Jaime M Guidry; Meerzaman, Daoud; Chen, Qing-Rong; Hsu, Chih Hao; Yan, Chunhua; Nguyen, Cu; Hu, Ying; Hermida, Leandro C; Davidsen, Tanja; Gesuwan, Patee; Ma, Yussanne; Zong, Zusheng; Mungall, Andrew J; Moore, Richard A; Marra, Marco A; Dome, Jeffrey S; Mullighan, Charles G; Ma, Jing; Wheeler, David A; Hampton, Oliver A; Ross, Nicole; Gastier-Foster, Julie M; Arold, Stefan T; Perlman, Elizabeth J

    2017-10-01

    We performed genome-wide sequencing and analyzed mRNA and miRNA expression, DNA copy number, and DNA methylation in 117 Wilms tumors, followed by targeted sequencing of 651 Wilms tumors. In addition to genes previously implicated in Wilms tumors (WT1, CTNNB1, AMER1, DROSHA, DGCR8, XPO5, DICER1, SIX1, SIX2, MLLT1, MYCN, and TP53), we identified mutations in genes not previously recognized as recurrently involved in Wilms tumors, the most frequent being BCOR, BCORL1, NONO, MAX, COL6A3, ASXL1, MAP3K4, and ARID1A. DNA copy number changes resulted in recurrent 1q gain, MYCN amplification, LIN28B gain, and MIRLET7A loss. Unexpected germline variants involved PALB2 and CHEK2. Integrated analyses support two major classes of genetic changes that preserve the progenitor state and/or interrupt normal development.

  1. A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor

    KAUST Repository

    Gadd, Samantha

    2017-08-21

    We performed genome-wide sequencing and analyzed mRNA and miRNA expression, DNA copy number, and DNA methylation in 117 Wilms tumors, followed by targeted sequencing of 651 Wilms tumors. In addition to genes previously implicated in Wilms tumors (WT1, CTNNB1, AMER1, DROSHA, DGCR8, XPO5, DICER1, SIX1, SIX2, MLLT1, MYCN, and TP53), we identified mutations in genes not previously recognized as recurrently involved in Wilms tumors, the most frequent being BCOR, BCORL1, NONO, MAX, COL6A3, ASXL1, MAP3K4, and ARID1A. DNA copy number changes resulted in recurrent 1q gain, MYCN amplification, LIN28B gain, and MIRLET7A loss. Unexpected germline variants involved PALB2 and CHEK2. Integrated analyses support two major classes of genetic changes that preserve the progenitor state and/or interrupt normal development.

  2. A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor

    KAUST Repository

    Gadd, Samantha; Huff, Vicki; Walz, Amy L; Ooms, Ariadne H A G; Armstrong, Amy E; Gerhard, Daniela S; Smith, Malcolm A; Auvil, Jaime M Guidry; Meerzaman, Daoud; Chen, Qing-Rong; Hsu, Chih Hao; Yan, Chunhua; Nguyen, Cu; Hu, Ying; Hermida, Leandro C; Davidsen, Tanja; Gesuwan, Patee; Ma, Yussanne; Zong, Zusheng; Mungall, Andrew J; Moore, Richard A; Marra, Marco A; Dome, Jeffrey S; Mullighan, Charles G; Ma, Jing; Wheeler, David A; Hampton, Oliver A; Ross, Nicole; Gastier-Foster, Julie M; Arold, Stefan T.; Perlman, Elizabeth J

    2017-01-01

    We performed genome-wide sequencing and analyzed mRNA and miRNA expression, DNA copy number, and DNA methylation in 117 Wilms tumors, followed by targeted sequencing of 651 Wilms tumors. In addition to genes previously implicated in Wilms tumors (WT1, CTNNB1, AMER1, DROSHA, DGCR8, XPO5, DICER1, SIX1, SIX2, MLLT1, MYCN, and TP53), we identified mutations in genes not previously recognized as recurrently involved in Wilms tumors, the most frequent being BCOR, BCORL1, NONO, MAX, COL6A3, ASXL1, MAP3K4, and ARID1A. DNA copy number changes resulted in recurrent 1q gain, MYCN amplification, LIN28B gain, and MIRLET7A loss. Unexpected germline variants involved PALB2 and CHEK2. Integrated analyses support two major classes of genetic changes that preserve the progenitor state and/or interrupt normal development.

  3. Please Ask Gently: Using Culturally Targeted Communication Strategies to Initiate End-of-Life Care Discussions With Older Chinese Americans.

    Science.gov (United States)

    Chi, Han-Lin; Cataldo, Janine; Ho, Evelyn Y; Rehm, Roberta S

    2018-01-01

    Health-care providers (HCPs) find facilitating end-of-life (EOL) care discussions challenging, especially with patients whose ethnicities differ from their own. Currently, there is little guidance on how to initiate and facilitate such discussions with older Chinese Americans (≥55 years) and their families. To explore communication strategies for HCPs to initiate EOL care discussions with older Chinese Americans in the San Francisco Bay Area. This qualitative (focused) ethnographic study included field observations and individual semistructured interviews with 14 community-dwelling older Chinese Americans who lived independently at home, 9 adult children, and 7 HCPs. Responses were analyzed using open coding, memos, and comparison across participants. The study participants emphasized the importance of assessing readiness for early EOL care discussions. All recommended using indirect communication approaches to determine older Chinese Americans' readiness. Indirect communication can be culturally targeted and applied at both system-wide (ie, health-care system) and individual (ie, HCP) levels. To institutionalize the practice, health-care facilities should implement EOL care discussion inquiries as part of routine during check-in or intake questionnaires. In individual practice, using depersonalized communication strategies to initiate the discussion was recommended to determine older Chinese Americans' readiness. Assessing readiness should be an essential and necessary action for early EOL care discussions. Culturally targeted assessment of older Chinese Americans includes using indirect communication approaches to initiate an EOL care discussion to determine their readiness. In addition to health-care system integration, providers should implement and evaluate proposed EOL discussion initiation prompts with their older Chinese American patients.

  4. BMI-1 targeting interferes with patient-derived tumor-initiating cell survival and tumor growth in prostate cancer

    Science.gov (United States)

    Yusuff, Shamila; Davis, Stephani; Flaherty, Kathleen; Huselid, Eric; Patrizii, Michele; Jones, Daniel; Cao, Liangxian; Sydorenko, Nadiya; Moon, Young-Choon; Zhong, Hua; Medina, Daniel J.; Kerrigan, John; Stein, Mark N.; Kim, Isaac Y.; Davis, Thomas W.; DiPaola, Robert S.; Bertino, Joseph R.; Sabaawy, Hatem E.

    2016-01-01

    Purpose Current prostate cancer (PCa) management calls for identifying novel and more effective therapies. Self-renewing tumor-initiating cells (TICs) hold intrinsic therapy-resistance and account for tumor relapse and progression. As BMI-1 regulates stem cell self-renewal, impairing BMI-1 function for TICs-tailored therapies appears to be a promising approach. Experimental design We have previously developed a combined immunophenotypic and time-of-adherence assay to identify CD49bhiCD29hiCD44hi cells as human prostate TICs. We utilized this assay with patient derived prostate cancer cells and xenograft models to characterize the effects of pharmacological inhibitors of BMI-1. Results We demonstrate that in cell lines and patient-derived TICs, BMI-1 expression is upregulated and associated with stem cell-like traits. From a screened library, we identified a number of post-transcriptional small molecules that target BMI-1 in prostate TICs. Pharmacological inhibition of BMI-1 in patient-derived cells significantly decreased colony formation in vitro and attenuated tumor initiation in vivo, thereby functionally diminishing the frequency of TICs, particularly in cells resistant to proliferation- and androgen receptor (AR)-directed therapies, without toxic effects on normal tissues. Conclusions Our data offer a paradigm for targeting TICs and support the development of BMI-1-targeting therapy for a more effective PCa treatment. PMID:27307599

  5. SF3B1-initiating mutations in MDS-RSs target lymphomyeloid hematopoietic stem cells.

    Science.gov (United States)

    Mortera-Blanco, Teresa; Dimitriou, Marios; Woll, Petter S; Karimi, Mohsen; Elvarsdottir, Edda; Conte, Simona; Tobiasson, Magnus; Jansson, Monika; Douagi, Iyadh; Moarii, Matahi; Saft, Leonie; Papaemmanuil, Elli; Jacobsen, Sten Eirik W; Hellström-Lindberg, Eva

    2017-08-17

    Mutations in the RNA splicing gene SF3B1 are found in >80% of patients with myelodysplastic syndrome with ring sideroblasts (MDS-RS). We investigated the origin of SF3B1 mutations within the bone marrow hematopoietic stem and progenitor cell compartments in patients with MDS-RS. Screening for recurrently mutated genes in the mononuclear cell fraction revealed mutations in SF3B1 in 39 of 40 cases (97.5%), combined with TET2 and DNMT3A in 11 (28%) and 6 (15%) patients, respectively. All recurrent mutations identified in mononuclear cells could be tracked back to the phenotypically defined hematopoietic stem cell (HSC) compartment in all investigated patients and were also present in downstream myeloid and erythroid progenitor cells. While in agreement with previous studies, little or no evidence for clonal ( SF3B1 mutation) involvement could be found in mature B cells, consistent involvement at the pro-B-cell progenitor stage was established, providing definitive evidence for SF3B1 mutations targeting lymphomyeloid HSCs and compatible with mutated SF3B1 negatively affecting lymphoid development. Assessment of stem cell function in vitro as well as in vivo established that only HSCs and not investigated progenitor populations could propagate the SF3B1 mutated clone. Upon transplantation into immune-deficient mice, SF3B1 mutated MDS-RS HSCs differentiated into characteristic ring sideroblasts, the hallmark of MDS-RS. Our findings provide evidence of a multipotent lymphomyeloid HSC origin of SF3B1 mutations in MDS-RS patients and provide a novel in vivo platform for mechanistically and therapeutically exploring SF3B1 mutated MDS-RS. © 2017 by The American Society of Hematology.

  6. Effect of initial-state target polarization on the single ionization of helium by 1-keV electron impact

    International Nuclear Information System (INIS)

    Sun Shi-Yan; Ma Xiao-Yan; Li Xia; Miao Xiang-Yang; Jia Xiang-Fu

    2012-01-01

    We report new results of triple differential cross sections for the single ionization of helium by 1-KeV electron impact at the ejection energy of 10 eV. Investigations have been made for both the perpendicular plane and the plane perpendicular to the momentum transfer geometries. The present calculation is based on the three-Coulomb wave function. Here we have also incorporated the effect of target polarization in the initial state. A comparison is made between the present calculation with the results of other theoretical methods and a recent experiment [Dürr M, Dimopoulou C, Najjari B, Dorn A, Bartschat K, Bray I, Fursa D V, Chen Z, Madison D H and Ullrich J 2008 Phys. Rev. A 77 032717]. At an impact energy of 1 KeV, the target polarization is found to induce a substantial change of the cross section for the ionization process. We observe that the effect of target polarization plays a dominant role in deciding the shape of triple differential cross sections. (atomic and molecular physics)

  7. New Mexico Museums and Cultural Centers

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset provides an initial version of the locations of museums and cultural centers in New Mexico, in point form, with limited attributes, compiled using...

  8. Targeted Cancer Therapy: Vital Oncogenes and a New Molecular Genetic Paradigm for Cancer Initiation Progression and Treatment

    Science.gov (United States)

    Willis, Rudolph E.

    2016-01-01

    It has been declared repeatedly that cancer is a result of molecular genetic abnormalities. However, there has been no working model describing the specific functional consequences of the deranged genomic processes that result in the initiation and propagation of the cancer process during carcinogenesis. We no longer need to question whether or not cancer arises as a result of a molecular genetic defect within the cancer cell. The legitimate questions are: how and why? This article reviews the preeminent data on cancer molecular genetics and subsequently proposes that the sentinel event in cancer initiation is the aberrant production of fused transcription activators with new molecular properties within normal tissue stem cells. This results in the production of vital oncogenes with dysfunctional gene activation transcription properties, which leads to dysfunctional gene regulation, the aberrant activation of transduction pathways, chromosomal breakage, activation of driver oncogenes, reactivation of stem cell transduction pathways and the activation of genes that result in the hallmarks of cancer. Furthermore, a novel holistic molecular genetic model of cancer initiation and progression is presented along with a new paradigm for the approach to personalized targeted cancer therapy, clinical monitoring and cancer diagnosis. PMID:27649156

  9. Doing Business in Mexico

    OpenAIRE

    Zimmermann, Thomas A.

    2002-01-01

    On 1 July 2001, a far-reaching free trade agreement between the EFTA States and Mexico entered into force. ”Doing Business in Mexico” provides targeted assistance to Swiss Small and Medium-Sized Enterprises (SME) that wish to tap the potential of Mexico as both an export destination and investment location. This comprehensive guide contains information and advice on market research, market entry, and investment in this fascinating country. Part I introduces the reader to this fascinating ...

  10. A demographic dividend of the FP2020 Initiative and the SDG reproductive health target: Case studies of India and Nigeria.

    Science.gov (United States)

    Li, Qingfeng; Rimon, Jose G

    2018-02-22

    Background: The demographic dividend, defined as the economic growth potential resulting from favorable shifts in population age structure following rapid fertility decline, has been widely employed to advocate improving access to family planning. The current framework focuses on the long-term potential, while the short-term benefits may also help persuade policy makers to invest in family planning. Methods: We estimate the short- and medium-term economic benefits from two major family planning goals: the Family Planning 2020 (FP2020)'s goal of adding 120 million modern contraceptive users by 2020; Sustainable Development Goals (SDG) 3.7 of ensuring universal access to family planning by 2030. We apply the cohort component method to World Population Prospects and National Transfer Accounts data. India and Nigeria, respectively the most populous Asian and African country under the FP2020 initiative, are used as case studies. Results: Meeting the FP2020 target implies that on average, the number of children that need to be supported by every 100 working-age people would decrease by 8 persons in India and 11 persons in Nigeria in 2020; the associated reduction remains at 8 persons in India, but increases to 14 persons in Nigeria by 2030 under the SDG 3.7. In India meeting the FP2020 target would yield a saving of US$18.2 billion (PPP) in consumption expenditures for children and youth in the year 2020 alone, and that increased to US$89.7 billion by 2030. In Nigeria the consumption saved would be US$2.5 billion in 2020 and $12.9 billion by 2030. Conclusions: The tremendous economic benefits from meeting the FP2020 and SDG family planning targets demonstrate the cost-effectiveness of investment in promoting access to contraceptive methods. The gap already apparent between the observed and targeted trajectories indicates tremendous missing opportunities. Accelerated progress is needed to achieve the FP2020 and SDG goals and so reap the demographic dividend.

  11. Opportunities for market-based programs worldwide that reduce greenhouse gas emissions: Initial Observations from Missions to the Philippines, South Africa, and Mexico

    International Nuclear Information System (INIS)

    Stanton-Hoyle, D.R.

    1998-01-01

    Globally, governments and industries are implementing innovative voluntary programs to reduce greenhouse gas emissions. Often these programs encourage groups to use cost effective technologies that capture market-based forces. These programs are successful because they capitalize on existing opportunities where both the environment and the participants can benefit (i.e., win-win opportunities). This paper documents efforts to investigate these kinds of win-win opportunities in three developing countries: the Philippines, South Africa, and Mexico. Initial observations are provided as fresh information from the field, drawing on six missions during the last nine months. Utility costs, interest rates, and overall economic health appear to critically affect opportunities in each country. By contrast, details of heating, ventilating and air-conditioning (HVAC) design and local climate were often important differences between countries. These affect opportunities, for example, to achieve significant savings from cooling systems or not. Looking at the success of ESCOs was somewhat surprising. One might expect to see the most successful ESCO activity where utility costs are high and upgrade opportunities are plentiful (such as in the Philippines). This was not the case, however, as research in the Philippines did not reveal even one active ESCO contract yet. Design practices for new construction were in need of the same thing that helps US design teams do a better job of energy-efficient design, better communications between design team members. Finally, industrial firms were doing a variety of EE upgrades in each country, but this level of activity was relatively small compared to what should be cost effective

  12. Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome

    DEFF Research Database (Denmark)

    da Rocha, Simão Teixeira; Boeva, Valentina; Escamilla-Del-Arenal, Martin

    2014-01-01

    complex, unlike at other parts of the genome, such as CG-rich regions, where Jarid2 and PRC2 binding are interdependent. Conversely, we show that Jarid2 loss prevents efficient PRC2 and H3K27me3 enrichment to Xist-coated chromatin. Jarid2 thus represents an important intermediate between PRC2 and Xist RNA......During X chromosome inactivation (XCI), the Polycomb Repressive Complex 2 (PRC2) is thought to participate in the early maintenance of the inactive state. Although Xist RNA is essential for the recruitment of PRC2 to the X chromosome, the precise mechanism remains unclear. Here, we demonstrate...... for the initial targeting of the PRC2 complex to the X chromosome during onset of XCI....

  13. Long-lasting insecticide-treated house screens and targeted treatment of productive breeding-sites for dengue vector control in Acapulco, Mexico.

    Science.gov (United States)

    Che-Mendoza, Azael; Guillermo-May, Guillermo; Herrera-Bojórquez, Josué; Barrera-Pérez, Mario; Dzul-Manzanilla, Felipe; Gutierrez-Castro, Cipriano; Arredondo-Jiménez, Juan I; Sánchez-Tejeda, Gustavo; Vazquez-Prokopec, Gonzalo; Ranson, Hilary; Lenhart, Audrey; Sommerfeld, Johannes; McCall, Philip J; Kroeger, Axel; Manrique-Saide, Pablo

    2015-02-01

    Long-lasting insecticidal net screens (LLIS) fitted to domestic windows and doors in combination with targeted treatment (TT) of the most productive Aedes aegypti breeding sites were evaluated for their impact on dengue vector indices in a cluster-randomised trial in Mexico between 2011 and 2013. Sequentially over 2 years, LLIS and TT were deployed in 10 treatment clusters (100 houses/cluster) and followed up over 24 months. Cross-sectional surveys quantified infestations of adult mosquitoes, immature stages at baseline (pre-intervention) and in four post-intervention samples at 6-monthly intervals. Identical surveys were carried out in 10 control clusters that received no treatment. LLIS clusters had significantly lower infestations compared to control clusters at 5 and 12 months after installation, as measured by adult (male and female) and pupal-based vector indices. After addition of TT to the intervention houses in intervention clusters, indices remained significantly lower in the treated clusters until 18 (immature and adult stage indices) and 24 months (adult indices only) post-intervention. These safe, simple affordable vector control tools were well-accepted by study participants and are potentially suitable in many regions at risk from dengue worldwide. © The author 2015. The World Health Organization has granted Oxford University Press permission for the reproduction of this article.

  14. PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target

    Science.gov (United States)

    Li, Jiarong; Karaplis, Andrew C.; Huang, Dao C.; Siegel, Peter M.; Camirand, Anne; Yang, Xian Fang; Muller, William J.; Kremer, Richard

    2011-01-01

    Parathyroid hormone–related protein (PTHrP) is a secreted factor expressed in almost all normal fetal and adult tissues. It is involved in a wide range of developmental and physiological processes, including serum calcium regulation. PTHrP is also associated with the progression of skeletal metastases, and its dysregulated expression in advanced cancers causes malignancy-associated hypercalcemia. Although PTHrP is frequently expressed by breast tumors and other solid cancers, its effects on tumor progression are unclear. Here, we demonstrate in mice pleiotropic involvement of PTHrP in key steps of breast cancer — it influences the initiation and progression of primary tumors and metastases. Pthrp ablation in the mammary epithelium of the PyMT-MMTV breast cancer mouse model caused a delay in primary tumor initiation, inhibited tumor progression, and reduced metastasis to distal sites. Mechanistically, it reduced expression of molecular markers of cell proliferation (Ki67) and angiogenesis (factor VIII), antiapoptotic factor Bcl-2, cell-cycle progression regulator cyclin D1, and survival factor AKT1. PTHrP also influenced expression of the adhesion factor CXCR4, and coexpression of PTHrP and CXCR4 was crucial for metastatic spread. Importantly, PTHrP-specific neutralizing antibodies slowed the progression and metastasis of human breast cancer xenografts. Our data identify what we believe to be new functions for PTHrP in several key steps of breast cancer and suggest that PTHrP may constitute a novel target for therapeutic intervention. PMID:22056386

  15. Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction

    Science.gov (United States)

    Lamb, Rebecca; Harrison, Hannah; Smith, Duncan L.; Townsend, Paul A.; Jackson, Thomas; Ozsvari, Bela; Martinez-Outschoorn, Ubaldo E.; Pestell, Richard G.; Howell, Anthony; Lisanti, Michael P.; Sotgia, Federica

    2015-01-01

    We have used an unbiased proteomic profiling strategy to identify new potential therapeutic targets in tumor-initiating cells (TICs), a.k.a., cancer stem cells (CSCs). Towards this end, the proteomes of mammospheres from two breast cancer cell lines were directly compared to attached monolayer cells. This allowed us to identify proteins that were highly over-expressed in CSCs and/or progenitor cells. We focused on ribosomal proteins and protein folding chaperones, since they were markedly over-expressed in mammospheres. Overall, we identified >80 molecules specifically associated with protein synthesis that were commonly upregulated in mammospheres. Most of these proteins were also transcriptionally upregulated in human breast cancer cells in vivo, providing evidence for their potential clinical relevance. As such, increased mRNA translation could provide a novel mechanism for enhancing the proliferative clonal expansion of TICs. The proteomic findings were functionally validated using known inhibitors of protein synthesis, via three independent approaches. For example, puromycin (which mimics the structure of tRNAs and competitively inhibits protein synthesis) preferentially targeted CSCs in both mammospheres and monolayer cultures, and was ~10-fold more potent for eradicating TICs, than “bulk” cancer cells. In addition, rapamycin, which inhibits mTOR and hence protein synthesis, was very effective at reducing mammosphere formation, at nanomolar concentrations. Finally, mammosphere formation was also markedly inhibited by methionine restriction, which mimics the positive effects of caloric restriction in cultured cells. Remarkably, mammosphere formation was >18-fold more sensitive to methionine restriction and replacement, as directly compared to monolayer cell proliferation. Methionine is absolutely required for protein synthesis, since every protein sequence starts with a methionine residue. Thus, the proliferation and survival of CSCs is very sensitive to

  16. Powering Mexico

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This article examines Mexico's demand for electricity and the market for independent power generation. The topics discussed in the article include the outlook for the 1990s for growth in Mexico's economy and energy demand, renewable energy, energy conservation, small-scale, off-grid renewable energy systems, and estimates of Mexico's market for electric power generating equipment

  17. When are they old enough to drink? Outcomes of an Australian social marketing intervention targeting alcohol initiation.

    Science.gov (United States)

    Jones, Sandra C; Andrews, Kelly; Francis, Kate L; Akram, Muhammad

    2018-04-01

    This paper reports on the evaluation of an Australian whole-of-community social marketing intervention targeting social norms, which aimed to reduce inflated perceptions of the prevalence of underage drinking and increase the age at which alcohol initiation is considered acceptable. A community-wide intervention was delivered in a single community over a period of 2 years, targeting adolescents, parents and community members. Pre-and post-intervention computer-assisted telephone interview surveys were conducted in the intervention and a matched comparison (control) community. A total of 417 respondents completed both surveys (215 in the intervention community and 202 in the control community). The intervention community saw an increase of 6 months in the average age at which it is perceived to be acceptable for young people to have a sip/taste of alcohol and 5 months in the average age at which it is perceived to be acceptable to have weak/watered down alcohol. Furthermore, there was a reduction in the perception of the prevalence of alcohol consumption by young people to a level consistent with actual underage drinking rates. In comparison, the control community saw no change in any of these variables. This study provides preliminary evidence that a whole-of-community social marketing intervention can change perceptions of the prevalence, and acceptability, of underage drinking. Given the central role of social norms in decisions regarding alcohol consumption, these changes have the potential to reduce parental supply and thus underage drinking. © 2018 Australasian Professional Society on Alcohol and other Drugs.

  18. Mexico Geoid Heights (MEXICO97)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This 2' geoid height grid for Mexico, and North-Central America, is the MEXICO97 geoid model. The computation used about one million terrestrial and marine gravity...

  19. Iron deficiency anemia referral to the hematologist. Real-world data from Mexico: the need for targeted teaching in primary care.

    Science.gov (United States)

    López-García, Yadith Karina; Colunga-Pedraza, Perla Rocío; Tarín-Arzaga, Luz; López Garza, Mariana Itzel; Jaime-Pérez, José Carlos; Gómez-Almaguer, David

    2018-04-11

    To determine the referral patterns and etiology of iron deficiency anemia (IDA) at an academic hematology center in northeast Mexico. We included all consecutive outpatients older than 16 years, non-pregnant, with IDA diagnosed in the Hematology Service of the Dr. José E. González University Hospital between January 2012 and May 2017. Appropriate data were collected retrospectively from the electronic medical record. Data regarding first medical contact (primary care physician or hematologist) were compared. One hundred fifty-three patients were included in this study. The median age was 43 years (interquartile range, 35-51) and 85.6% were female; 128 (83.7%) patients were seen by a primary care physician before our evaluation. Abnormal uterine bleeding (AUB) was the cause of IDA in 76 patients (49.6%), gastrointestinal bleeding (GIB) in 31 (20.2%), H. pylori infection in 12 (7.8%), urinary tract bleeding in three (1.9%) and malabsorption-syndrome in two (1.3%). The etiology remained unknown in 29 (18.9%). The p value was <0.05 between groups according to the first medical contact, including frequency of at least one sign or symptom of IDA, previous use of iron supplementation and blood transfusion, comorbidities, complete blood count at diagnosis, and resolution rates of anemia. The majority of our IDA patients were referred by another physician. Nearly half of the patients with IDA had AUB. IDA remains a diagnostic challenge for first contact physicians requiring a targeted educational intervention to improve IDA awareness and diagnostic skills.

  20. Practical aspects of treatment with target specific anticoagulants: initiation, payment and current market, transitions, and venous thromboembolism treatment.

    Science.gov (United States)

    Mahan, Charles E

    2015-04-01

    Target specific anticoagulants (TSOACs) have recently been introduced to the US market for multiple indications including venous thromboembolism (VTE) prevention in total hip and knee replacement surgeries, VTE treatment and reduction in the risk of stroke in patients with non-valvular atrial fibrillation (NVAF). Currently, three TSOACs are available including rivaroxaban, apixaban, and dabigatran with edoxaban currently under Food and Drug Administration review for VTE treatment and stroke prevention in NVAF. The introduction of these agents has created a paradigm shift in anticoagulation by considerably simplifying treatment and anticoagulant initiation for patients by giving clinicians the opportunity to use a rapid onset, rapid offset, oral agent. The availability of these rapid onset TSOACs is allowing for outpatient treatment of low risk pulmonary embolism and deep vein thrombosis which can greatly reduce healthcare costs by avoiding inpatient hospitalizations and treatment for the disease. Additionally with this practice, the complications of an inpatient hospitalization may also be avoided such as nosocomial infections. Single-agent approaches with TSOACs represent a paradigm shift in the treatment of VTE versus the complicated overlap of a parenteral agent with warfarin. Transitions between anticoagulants, including TSOACs, are a high-risk period for the patient, and clinicians must carefully consider patient characteristics such as renal function as well as the agents that are being transitioned. TSOAC use appears to be growing slowly with improved payment coverage throughout the US.

  1. Life histories predict genetic diversity and population structure within three species of octopus targeted by small-scale fisheries in Northwest Mexico

    Science.gov (United States)

    Ceballos-Vázquez, Bertha P.; Arellano-Martínez, Marcial; García-Rodríguez, Francisco J.; Culver, Melanie; Reyes-Bonilla, Hector

    2018-01-01

    The fishery for octopus in Northwest Mexico has increased to over 2,000 tons annually, but to date the specific composition of the catch has been ignored. With at least three main species targeted by artisanal fisheries in the region with distinct life histories, the lack of basic biological information about the distribution, metapopulation size and structure of each species could impede effective fisheries management to avoid overexploitation. We tested if different life histories of three species of octopus could help predict observed patterns of genetic diversity, population dynamics, structure and connectivity and how this information could be relevant to the sustainable management of the fishery. We sequenced two mitochondrial genes and genotyped seven nuclear microsatellite loci to identify the distribution of each species in 20 locations from the Gulf of California and the west coast of the Baja California peninsula. We tested five hypotheses derived from population genetic theory based on differences in the fecundity and dispersal potential for each species. We discovered that Octopus bimaculoides with low fecundity and direct development (without a planktonic phase) had lower average effective population size and genetic diversity, but higher levels of kinship, population structure, and richness of private alleles, than the other two species. These features indicated limited dispersal and high local recruitment. In contrast, O. bimaculatus and O. hubbsorum with higher fecundity and planktonic phase as paralarvae had higher effective population size and genetic diversity, and overall lower kinship and population structure than O. bimaculoides. These observations supported higher levels of gene flow over a larger geographical scale. O. bimaculatus with the longest planktonic paralarval duration and therefore larger dispersal potential had differences in the calculated parameters possibly associated with increased connectivity. We propose O

  2. Gills are an initial target of zinc oxide nanoparticles in oysters Crassostrea gigas, leading to mitochondrial disruption and oxidative stress

    International Nuclear Information System (INIS)

    Trevisan, Rafael; Delapedra, Gabriel; Mello, Danielle F.; Arl, Miriam; Schmidt, Éder C.; Meder, Fabian; Monopoli, Marco; Cargnin-Ferreira, Eduardo; Bouzon, Zenilda L.; Fisher, Andrew S.; Sheehan, David; Dafre, Alcir L.

    2014-01-01

    count). At 24 h post exposure, decreased (−29%) glutathione reductase (GR) activity was observed in gills, but other biochemical responses were observed only after 48 h of exposure: lower GR activity (−28%) and levels of protein thiols (−21%), increased index of lipid peroxidation (+49%) and GPx activity (+26%). In accordance with ultrastructural changes and zinc load, digestive gland showed delayed biochemical responses. Except for a decreased GR activity (−47%) at 48 h post exposure, the biochemical alterations seen in gills were not present in digestive gland. The results indicate that gills are able to incorporate zinc prior (24 h) to digestive gland (48 h), leading to earlier mitochondrial disruption and oxidative stress. Our data suggest that gills are the initial target of ZnONP and that mitochondria are organelles particularly susceptible to ZnONP in C. gigas

  3. Gills are an initial target of zinc oxide nanoparticles in oysters Crassostrea gigas, leading to mitochondrial disruption and oxidative stress

    Energy Technology Data Exchange (ETDEWEB)

    Trevisan, Rafael; Delapedra, Gabriel; Mello, Danielle F.; Arl, Miriam [Department of Biochemistry, Federal University of Santa Catarina, 88040-900 Florianópolis, SC (Brazil); Schmidt, Éder C. [Department of Cell Biology, Embryology and Genetic, Federal University of Santa Catarina, 88049-900 Florianópolis, SC (Brazil); Meder, Fabian; Monopoli, Marco [Centre for Bionano Interactions, University College Dublin, Dublin (Ireland); Cargnin-Ferreira, Eduardo [Federal Institute of Santa Catarina, Campus Garopaba, Laboratory of Histological Markers, 88495-000 Garopaba, SC (Brazil); Bouzon, Zenilda L. [Department of Cell Biology, Embryology and Genetic, Federal University of Santa Catarina, 88049-900 Florianópolis, SC (Brazil); Fisher, Andrew S. [School of Geography, Earth and Environmental Sciences, University of Plymouth, PL4 8AA Plymouth (United Kingdom); Sheehan, David [Department of Biochemistry, University College Cork, Cork (Ireland); Dafre, Alcir L., E-mail: alcir.dafre@ufsc.br [Department of Biochemistry, Federal University of Santa Catarina, 88040-900 Florianópolis, SC (Brazil)

    2014-08-15

    hemocyte count). At 24 h post exposure, decreased (−29%) glutathione reductase (GR) activity was observed in gills, but other biochemical responses were observed only after 48 h of exposure: lower GR activity (−28%) and levels of protein thiols (−21%), increased index of lipid peroxidation (+49%) and GPx activity (+26%). In accordance with ultrastructural changes and zinc load, digestive gland showed delayed biochemical responses. Except for a decreased GR activity (−47%) at 48 h post exposure, the biochemical alterations seen in gills were not present in digestive gland. The results indicate that gills are able to incorporate zinc prior (24 h) to digestive gland (48 h), leading to earlier mitochondrial disruption and oxidative stress. Our data suggest that gills are the initial target of ZnONP and that mitochondria are organelles particularly susceptible to ZnONP in C. gigas.

  4. Angular distribution of thick-target bremsstrahlung produced by electrons with initial energies ranging from 10 to 20 keV incident on Ag

    Energy Technology Data Exchange (ETDEWEB)

    Gonzales, D.; Cavness, B.; Williams, S. [Department of Physics, Angelo State University, San Angelo, Texas 76909 (United States)

    2011-11-15

    Experimental results are presented comparing the intensities of the bremsstrahlung produced by electrons with initial energies ranging from 10 to 20 keV incident on a thick Ag target, measured at forward angles in the range of 0 degree sign to 55 degree sign . When the data are corrected for attenuation due to photon absorption within the target, the results indicate that the detected radiation is distributed anisotropically only at photon energies k that are approximately equal to the initial energy of the incident electrons E{sub 0}. The results of our experiments suggest that, as k/E{sub 0}{yields} 0, the detected radiation essentially becomes isotropic due primarily to the scattering of electrons within the target. A comparison to the theory of Kissel et al.[At. Data Nucl. Data Tables 28, 381 (1983)] suggests that the angular distribution of bremsstrahlung emitted by electrons incident on thick targets is similar to the angular distribution of bremsstrahlung emitted by electrons incident on free-atom targets only when k/E{sub 0}{approx_equal} 1. The experimental data also are in approximate agreement with the angular distribution predictions of the Monte Carlo program penelope.

  5. Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage

    DEFF Research Database (Denmark)

    Syljuåsen, Randi G; Sørensen, Claus Storgaard; Hansen, Lasse Tengbjerg

    2005-01-01

    by increased amounts of nonextractable RPA protein, formation of single-stranded DNA, and induction of DNA strand breaks. Moreover, these responses were prevented by siRNA-mediated downregulation of Cdk2 or the replication initiation protein Cdc45, or by addition of the CDK inhibitor roscovitine. We propose...

  6. Factors associated with reaching or not reaching target HbA1c after initiation of basal or premixed insulin in patients with type 2 diabetes.

    Science.gov (United States)

    Scheen, A J; Schmitt, H; Jiang, H H; Ivanyi, T

    2017-02-01

    To evaluate factors associated with reaching or not reaching target glycated haemoglobin (HbA 1c ) levels by analysing the respective contributions of fasting hyperglycaemia (FHG), also referred to as basal hyperglycaemia, vs postprandial hyperglycaemia (PHG) before and after initiation of a basal or premixed insulin regimen in patients with type 2 diabetes. This post-hoc analysis of insulin-naïve patients in the DURABLE study randomised to receive either insulin glargine or insulin lispro mix 25 evaluated the percentages of patients achieving a target HbA 1c of <7.0% (<53mmol/mol) per baseline HbA 1c quartiles, and the effect of each insulin regimen on the relative contributions of PHG and FHG to overall hyperglycaemia. Patients had comparable demographic characteristics and similar HbA 1c and FHG values at baseline in each HbA 1c quartile regardless of whether they reached the target HbA 1c . The higher the HbA 1c quartile, the greater was the decrease in HbA 1c , but also the smaller the percentage of patients achieving the target HbA 1c . HbA 1c and FHG decreased more in patients reaching the target, resulting in significantly lower values at endpoint in all baseline HbA 1c quartiles with either insulin treatment. Patients not achieving the target HbA 1c had slightly higher insulin doses, but lower total hypoglycaemia rates. Smaller decreases in FHG were associated with not reaching the target HbA 1c , suggesting a need to increase basal or premixed insulin doses to achieve targeted fasting plasma glucose and improve patient response before introducing more intensive prandial insulin regimens. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  7. Therapeutic Targeting of the Mitochondria Initiates Excessive Superoxide Production and Mitochondrial Depolarization Causing Decreased mtDNA Integrity.

    Science.gov (United States)

    Pokrzywinski, Kaytee L; Biel, Thomas G; Kryndushkin, Dmitry; Rao, V Ashutosh

    2016-01-01

    Mitochondrial dysregulation is closely associated with excessive reactive oxygen species (ROS) production. Altered redox homeostasis has been implicated in the onset of several diseases including cancer. Mitochondrial DNA (mtDNA) and proteins are particularly sensitive to ROS as they are in close proximity to the respiratory chain (RC). Mitoquinone (MitoQ), a mitochondria-targeted redox agent, selectively damages breast cancer cells possibly through damage induced via enhanced ROS production. However, the effects of MitoQ and other triphenylphosphonium (TPP+) conjugated agents on cancer mitochondrial homeostasis remain unknown. The primary objective of this study was to determine the impact of mitochondria-targeted agent [(MTAs) conjugated to TPP+: mitoTEMPOL, mitoquinone and mitochromanol-acetate] on mitochondrial physiology and mtDNA integrity in breast (MDA-MB-231) and lung (H23) cancer cells. The integrity of the mtDNA was assessed by quantifying the degree of mtDNA fragmentation and copy number, as well as by measuring mitochondrial proteins essential to mtDNA stability and maintenance (TFAM, SSBP1, TWINKLE, POLG and POLRMT). Mitochondrial status was evaluated by measuring superoxide production, mitochondrial membrane depolarization, oxygen consumption, extracellular acidification and mRNA or protein levels of the RC complexes along with TCA cycle activity. In this study, we demonstrated that all investigated MTAs impair mitochondrial health and decrease mtDNA integrity in MDA-MB-231 and H23 cells. However, differences in the degree of mitochondrial damage and mtDNA degradation suggest unique properties among each MTA that may be cell line, dose and time dependent. Collectively, our study indicates the potential for TPP+ conjugated molecules to impair breast and lung cancer cells by targeting mitochondrial homeostasis.

  8. Influence of socioeconomic and demographic status on spirometry testing in patients initiating medication targeting obstructive lung disease: a population-based cohort study

    Science.gov (United States)

    2013-01-01

    Background Socioeconomic status is known to influence the prevalence, severity and mortality of obstructive lung diseases, but it is uncertain whether it affects the use of diagnostic spirometry in patients initiating treatment for these conditions. The objective of this paper was to examine a possible association between education, income, labour market affiliation, cohabitation status and having spirometry performed when initiating medication targeting obstructive pulmonary disease. Methods We conducted a population-based cohort study. Danish national registers were linked, retrieving data on prescriptions, spirometry testing, socioeconomic and demographic variables in all first time users of medication targeting obstructive lung disease in 2008. Results A total of 37,734 persons were included and approximately half of the cohort had spirometry performed. Among medication users under 65 years of age, being unemployed was significantly associated with reduced odds of having spirometry performed, the strongest association was seen in men (OR = 0.82, CI = 0.73-0.91). Medium income was associated with increased odds of having spirometry performed in men (OR = 1.18, CI = 1.06-1.30) and high educational level (>12 years) was associated with reduced odds of having spirometry performed in women (OR = 0.86, CI = 0.78-0.94). Cohabitation status was not associated with having spirometry performed. Among medication users over 65 years of age, living alone was associated with reduced odds of having spirometry performed among men (OR = 0.78, CI = 0.69-0.88). Conclusion Social inequity in spirometry testing among patients initiating medication targeting obstructive lung disease was confirmed in this study. Increased focus on spirometry testing among elderly men living alone, among the unemployed and among women with higher education is required when initiating medication. PMID:23768408

  9. A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor. | Office of Cancer Genomics

    Science.gov (United States)

    We performed genome-wide sequencing and analyzed mRNA and miRNA expression, DNA copy number, and DNA methylation in 117 Wilms tumors, followed by targeted sequencing of 651 Wilms tumors. In addition to genes previously implicated in Wilms tumors (WT1, CTNNB1, AMER1, DROSHA, DGCR8, XPO5, DICER1, SIX1, SIX2, MLLT1, MYCN, and TP53), we identified mutations in genes not previously recognized as recurrently involved in Wilms tumors, the most frequent being BCOR, BCORL1, NONO, MAX, COL6A3, ASXL1, MAP3K4, and ARID1A.

  10. Identification and Initial Characterization of the Effectors of an Anther Smut Fungus and Potential Host Target Proteins

    Directory of Open Access Journals (Sweden)

    Venkata S. Kuppireddy

    2017-11-01

    Full Text Available (1 Background: Plant pathogenic fungi often display high levels of host specificity and biotrophic fungi; in particular, they must manipulate their hosts to avoid detection and to complete their obligate pathogenic lifecycles. One important strategy of such fungi is the secretion of small proteins that serve as effectors in this process. Microbotryum violaceum is a species complex whose members infect members of the Caryophyllaceae; M. lychnidis-dioicae, a parasite on Silene latifolia, is one of the best studied interactions. We are interested in identifying and characterizing effectors of the fungus and possible corresponding host targets; (2 Methods: In silico analysis of the M. lychnidis-dioicae genome and transcriptomes allowed us to predict a pool of small secreted proteins (SSPs with the hallmarks of effectors, including a lack of conserved protein family (PFAM domains and also localized regions of disorder. Putative SSPs were tested for secretion using a yeast secretion trap method. We then used yeast two-hybrid analyses for candidate-secreted effectors to probe a cDNA library from a range of growth conditions of the fungus, including infected plants; (3 Results: Roughly 50 SSPs were identified by in silico analysis. Of these, 4 were studied further and shown to be secreted, as well as examined for potential host interactors. One of the putative effectors, MVLG_01732, was found to interact with Arabidopsis thaliana calcium-dependent lipid binding protein (AtCLB and with cellulose synthase interactive protein 1 orthologues; and (4 Conclusions: The identification of a pool of putative effectors provides a resource for functional characterization of fungal proteins that mediate the delicate interaction between pathogen and host. The candidate targets of effectors, e.g., AtCLB, involved in pollen germination suggest tantalizing insights that could drive future studies.

  11. Advances in in vivo EPR Tooth Biodosimetry: Meeting the targets for initial triage following a large-scale radiation event

    International Nuclear Information System (INIS)

    Flood, Ann Barry; Schreiber, Wilson; Du, Gaixin; Wood, Victoria A.; Kmiec, Maciej M.; Petryakov, Sergey V.; Williams, Benjamin B.; Swartz, Harold M.; Demidenko, Eugene; Boyle, Holly K.; Dong, Ruhong; Geimer, Shireen; Jarvis, Lesley A.; Kobayashi, Kyo; Nicolalde; Roberto, J.; Crist, Jason; Gupta, Ankit; Raynolds, Timothy; Brugger, Spencer; Budzioh, Pawel; Carr, Brandon; Feldman, Matthew; Gimi, Barjor; Grinberg, Oleg; Krymov, Vladimir; Lesniewski, Piotr; Mariani, Michael; Meaney, Paul M.; Rychert, Kevin M.; Salikhov, Ildar; Tipikin, Dmitriy S.; Tseytlin, Mark; Edwards, Brian R.; Herring, Christopher D.; Lindsay, Catherine; Rosenbaum, Traci; Ali, Arif; Carlson, David; Froncisz, Wojciech; Hirata, Hiroshi; Sidabras, Jason; Swarts, Steven G.

    2016-01-01

    Several important recent advances in the development and evolution of in vivo Tooth Biodosimetry using Electron Paramagnetic Resonance (EPR) allow its performance to meet or exceed the U.S. targeted requirements for accuracy and ease of operation and throughput in a large-scale radiation event. Ergonomically based changes to the magnet, coupled with the development of rotation of the magnet and advanced software to automate collection of data, have made it easier and faster to make a measurement. From start to finish, measurements require a total elapsed time of 5 min, with data acquisition taking place in less than 3 min. At the same time, the accuracy of the data for triage of large populations has improved, as indicated using the metrics of sensitivity, specificity and area under the ROC curve. Applying these standards to the intended population, EPR in vivo Tooth Biodosimetry has approximately the same diagnostic accuracy as the purported 'gold standard' (dicentric chromosome assay). Other improvements include miniaturisation of the spectrometer, leading to the creation of a significantly lighter and more compact prototype that is suitable for transporting for Point of Care (POC) operation and that can be operated off a single standard power outlet. Additional advancements in the resonator, including use of a disposable sensing loop attached to the incisor tooth, have resulted in a biodosimetry method where measurements can be made quickly with a simple 5-step workflow and by people needing only a few minutes of training (which can be built into the instrument as a training video). In sum, recent advancements allow this prototype to meet or exceed the US Federal Government's recommended targets for POC biodosimetry in large-scale events. (authors)

  12. Final Environmental Assessment for the Establishment of an Air-to-Surface Helicopter Gunnery Training Target Set at White Sands Missile Range, New Mexico

    Science.gov (United States)

    2007-12-01

    Mockingbird Mountains. The range would consist of two target groups, with armored personnel carrier hulks in the target groups. One Helicopter...valley between Fairview Mountain and the Mockingbird Mountains (see Figure 2-2). The range would consist of two target groups, with armored personnel...pursue, hunt, take, capture, or kill ; attempt to take, capture, or kill ; possess, offer to or sell, barter, purchase, deliver, or cause to be shipped

  13. The role of landowners in jaguar conservation in Sonora, Mexico.

    Science.gov (United States)

    Rosas-Rosas, Octavio C; Valdez, Raul

    2010-04-01

    The northernmost known breeding population of jaguars occurs in the municipality of Nácori Chico, Sonora, Mexico about 270 km from the United States-Mexico border and may be the source from which jaguars sighted in the United States dispersed. Since 1999 at least 11 jaguars (Panthera onca) had been illegally killed in the area due to predator control programs. We initiated a jaguar landowner-based conservation plan in 2004. The eight participating landowners agreed to suspend predator control programs targeting jaguars and pumas (Puma concolor) only if cattle losses were compensated. A private outfitter, with the consent of landowners, initiated white-tailed deer (Odocoileus virginianus) hunts in 2004 and agreed to pay the group of participating landowners US$1500 for every deer hunt permit sold. The funds paid to the landowners from deer hunts were sufficient to convince landowners to suspend all predator-control efforts of jaguars and pumas. The involvement of landowners in the jaguar conservation program in northeastern Sonora is a successful, private, wildlife-conservation initiative that provides an example for jaguar conservation efforts in northern Mexico.

  14. A dimensionless dynamic contrast enhanced MRI parameter for intra-prostatic tumour target volume delineation: initial comparison with histology

    Science.gov (United States)

    Hrinivich, W. Thomas; Gibson, Eli; Gaed, Mena; Gomez, Jose A.; Moussa, Madeleine; McKenzie, Charles A.; Bauman, Glenn S.; Ward, Aaron D.; Fenster, Aaron; Wong, Eugene

    2014-03-01

    Purpose: T2 weighted and diffusion weighted magnetic resonance imaging (MRI) show promise in isolating prostate tumours. Dynamic contrast enhanced (DCE)-MRI has also been employed as a component in multi-parametric tumour detection schemes. Model-based parameters such as Ktrans are conventionally used to characterize DCE images and require arterial contrast agent (CR) concentration. A robust parameter map that does not depend on arterial input may be more useful for target volume delineation. We present a dimensionless parameter (Wio) that characterizes CR wash-in and washout rates without requiring arterial CR concentration. Wio is compared to Ktrans in terms of ability to discriminate cancer in the prostate, as demonstrated via comparison with histology. Methods: Three subjects underwent DCE-MRI using gadolinium contrast and 7 s imaging temporal resolution. A pathologist identified cancer on whole-mount histology specimens, and slides were deformably registered to MR images. The ability of Wio maps to discriminate cancer was determined through receiver operating characteristic curve (ROC) analysis. Results: There is a trend that Wio shows greater area under the ROC curve (AUC) than Ktrans with median AUC values of 0.74 and 0.69 respectively, but the difference was not statistically significant based on a Wilcoxon signed-rank test (p = 0.13). Conclusions: Preliminary results indicate that Wio shows potential as a tool for Ktrans QA, showing similar ability to discriminate cancer in the prostate as Ktrans without requiring arterial CR concentration.

  15. Stem-like tumor-initiating cells isolated from IL13Rα2 expressing gliomas are targeted and killed by IL13-zetakine-redirected T Cells.

    Science.gov (United States)

    Brown, Christine E; Starr, Renate; Aguilar, Brenda; Shami, Andrew F; Martinez, Catalina; D'Apuzzo, Massimo; Barish, Michael E; Forman, Stephen J; Jensen, Michael C

    2012-04-15

    To evaluate IL13Rα2 as an immunotherapeutic target for eliminating glioma stem-like cancer initiating cells (GSC) of high-grade gliomas, with particular focus on the potential of genetically engineered IL13Rα2-specific primary human CD8(+) CTLs (IL13-zetakine(+) CTL) to target this therapeutically resistant glioma subpopulation. A panel of low-passage GSC tumor sphere (TS) and serum-differentiated glioma lines were expanded from patient glioblastoma specimens. These glioblastoma lines were evaluated for expression of IL13Rα2 and for susceptibility to IL13-zetakine(+) CTL-mediated killing in vitro and in vivo. We observed that although glioma IL13Rα2 expression varies between patients, for IL13Rα2(pos) cases this antigen was detected on both GSCs and more differentiated tumor cell populations. IL13-zetakine(+) CTL were capable of efficient recognition and killing of both IL13Rα2(pos) GSCs and IL13Rα2(pos) differentiated cells in vitro, as well as eliminating glioma-initiating activity in an orthotopic mouse tumor model. Furthermore, intracranial administration of IL13-zetakine(+) CTL displayed robust antitumor activity against established IL13Rα2(pos) GSC TS-initiated orthotopic tumors in mice. Within IL13Rα2 expressing high-grade gliomas, this receptor is expressed by GSCs and differentiated tumor populations, rendering both targetable by IL13-zetakine(+) CTLs. Thus, our results support the potential usefullness of IL13Rα2-directed immunotherapeutic approaches for eradicating therapeutically resistant GSC populations. ©2012 AACR.

  16. Target temperature management of 33°C and 36°C in patients with out-of-hospital cardiac arrest with initial non-shockable rhythm

    DEFF Research Database (Denmark)

    Frydland, Martin; Kjaergaard, Jesper; Erlinge, David

    2015-01-01

    PURPOSE: Despite a lack of randomized trials in comatose survivors of out-of-hospital cardiac arrest (OHCA) with an initial non-shockable rhythm (NSR), guidelines recommend induced hypothermia to be considered in these patients. We assessed the effect on outcome of two levels of induced hypothermia...... in comatose patient resuscitated from NSR. METHODS: Hundred and seventy-eight patients out of 950 in the TTM trial with an initial NSR were randomly assigned to targeted temperature management at either 33°C (TTM33, n=96) or 36°C (TTM36, n=82). We assessed mortality, neurologic function (Cerebral Performance...... Score (CPC) and modified Rankin Scale (mRS)), and organ dysfunction (Sequential Organ Failure Assessment (SOFA) score). RESULTS: Patients with NSR were older, had longer time to ROSC, less frequently had bystander CPR and had higher lactate levels at admission compared to patients with shockable rhythm...

  17. Optimised labeling, preclinical and initial clinical aspects of CCK-2 receptor-targeting with 3 radiolabeled peptides

    International Nuclear Information System (INIS)

    Breeman, Wouter A.P.; Froeberg, A.C.; Blois, E. de; Gameren, A. van; Melis, M.; Jong, M. de; Maina, T.; Nock, B.A.; Erion, J.L.; Maecke, H.R.; Krenning, E.P.

    2008-01-01

    Medullary thyroid carcinoma (MTC) expresses CCK-2 receptors. 111 In-labeled DOTA-DGlu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH 2 (DOTA-MG11), DOTA-DAsp-Tyr-Nle-Gly-Trp-Nle-Asp-Phe-NH 2 (DOTA-CCK), and 99m Tc-labeled N 4 -Gly-DGlu-(Glu) 5 -Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH 2 ( 99m Tc-Demogastrin 2) are analogs developed for CCK-2 receptor-targeted scintigraphy. All 3 radiolabeled analogs were selected on the basis of their high CCK-2 receptor affinity and their good in vitro serum stability, with in vitro serum t 1/2 values of several hours. Radiolabeling of DOTA-peptides with 111 In requires a heating procedure, typically in the range of 80 deg. - 100 deg. C up to 30 min. Following this procedure with DOTA-MG11 resulted in a >98 % incorporation of 111 In, however, with a radiochemical purity (RCP) of 111 In involved 5 min heating at 80 deg. C and led to an incorporation of 111 In of >98 %. In addition, all analogs were radiolabeled in the presence of quenchers to prevent radiolysis and oxidation resulting in a RCP of >90 %. All 3 radiolabeled analogs were i.v. administered to 6 MTC patients: radioactivity cleared rapidly by the kidneys, with no significant differences in the excretion pattern of the 3 radiotracers. All 3 radiolabeled analogs exhibited a low in vivo stability in patients, as revealed during analysis of blood samples, with the respective t 1/2 found in the order of minutes. In patient blood, the rank of radiopeptide in vivo stability was: 99m Tc-Demogastrin 2 (t 1/2 10-15 min)> 111 In-DOTA-CCK (t 1/2 ∼5-10 min)> 111 In-DOTA-MG11 (t 1/2 <5 min)

  18. Optimised labeling, preclinical and initial clinical aspects of CCK-2 receptor-targeting with 3 radiolabeled peptides

    Energy Technology Data Exchange (ETDEWEB)

    Breeman, Wouter A.P. [Department of Nuclear Medicine, Erasmus MC Rotterdam' s 3015 CE Rotterdam (Netherlands)], E-mail: w.a.p.breeman@erasmusmc.nl; Froeberg, A.C.; Blois, E. de; Gameren, A. van; Melis, M.; Jong, M. de [Department of Nuclear Medicine, Erasmus MC Rotterdam' s 3015 CE Rotterdam (Netherlands); Maina, T.; Nock, B.A. [Molecular Radiopharmacy Section, I/R-RP, NCSR ' Demokritos' , Athens (Greece); Erion, J.L. [BioSynthema Inc., St. Louis, MO (United States); Maecke, H.R. [Radiological Chemistry, University Hospital Basel (Switzerland); Krenning, E.P. [Department of Nuclear Medicine, Erasmus MC Rotterdam' s 3015 CE Rotterdam (Netherlands); Department of Internal Medicine, Erasmus MC, Rotterdam (Netherlands)

    2008-11-15

    Medullary thyroid carcinoma (MTC) expresses CCK-2 receptors. {sup 111}In-labeled DOTA-DGlu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH{sub 2} (DOTA-MG11), DOTA-DAsp-Tyr-Nle-Gly-Trp-Nle-Asp-Phe-NH{sub 2} (DOTA-CCK), and {sup 99m}Tc-labeled N{sub 4}-Gly-DGlu-(Glu){sub 5}-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH{sub 2} ({sup 99m}Tc-Demogastrin 2) are analogs developed for CCK-2 receptor-targeted scintigraphy. All 3 radiolabeled analogs were selected on the basis of their high CCK-2 receptor affinity and their good in vitro serum stability, with in vitro serum t{sub 1/2} values of several hours. Radiolabeling of DOTA-peptides with {sup 111}In requires a heating procedure, typically in the range of 80 deg. - 100 deg. C up to 30 min. Following this procedure with DOTA-MG11 resulted in a >98 % incorporation of {sup 111}In, however, with a radiochemical purity (RCP) of <50 %. The decrease in RCP was found to be due to oxidation of the methionine residue in the molecule. Moreover, this oxidized compound lost its CCK-2 receptor affinity. Therefore, conditions during radiolabeling were optimised: labeling of DOTA-MG11 and DOTA-CCK with {sup 111}In involved 5 min heating at 80 deg. C and led to an incorporation of {sup 111}In of >98 %. In addition, all analogs were radiolabeled in the presence of quenchers to prevent radiolysis and oxidation resulting in a RCP of >90 %. All 3 radiolabeled analogs were i.v. administered to 6 MTC patients: radioactivity cleared rapidly by the kidneys, with no significant differences in the excretion pattern of the 3 radiotracers. All 3 radiolabeled analogs exhibited a low in vivo stability in patients, as revealed during analysis of blood samples, with the respective t{sub 1/2} found in the order of minutes. In patient blood, the rank of radiopeptide in vivo stability was: {sup 99m}Tc-Demogastrin 2 (t{sub 1/2} 10-15 min)>{sup 111}In-DOTA-CCK (t{sub 1/2}{approx}5-10 min)>{sup 111}In-DOTA-MG11 (t{sub 1/2}<5 min)

  19. Neuropsychology in Mexico.

    Science.gov (United States)

    Ostrosky Shejet, Feggy; Velez Garcia, Alicia

    2016-11-01

    This invited paper explores the diverse pathways that have led to the development of neuropsychology in Mexico. The authors conducted a review of the literature and their own experiences to describe the seminal events and people relevant to the development of this area of research and practice. The master's degree is the usual level of educational attainment for those who wish to practice clinical neuropsychology. As of now, there is not a board certification process in neuropsychology, although there is one in clinical psychology. Neuropsychology and other mental health disciplines in Mexico and Latin America have historically been poorly funded, and have lacked optimal means of communication as to research findings and clinical initiatives and standards. However, there is reason to think that this will be improved upon in coming years.

  20. Youth programmes in Mexico.

    Science.gov (United States)

    Rodriguez De Macias, G

    1990-12-01

    Research indicates that in-school adolescents in Mexico have their first sexual contact at the average age of 15.5 years. In 50% of cases, such contact is with a boyfriend or girlfriend, 28.1% with a fiance, and 18.3% with a prostitute. First sexual intercourse occurs with a spouse in only 1.3% of cases. Since only one in six young people in Mexico use a form of contraception, many unwanted pregnancies outside of marriage result. 450,000 births in 1989 were to mothers below 20 years old, with 15% of births annually being among teenage mothers. An estimated three million abortions occur annually in Mexico, and abortions are the fifth major cause of death at the national level. Teen pregnancy is decisively linked with poor living conditions and life expectancy, a relatively lower level of education, and rural residence. As for psychological and anthropological variables, most teens who become pregnant belong to large, unstable families with poor family communication, and are characterized as submissive, highly dependent, and of low self-esteem. Targeting students, workers, and other youths, the MEXFAM Youth Program selects and trains program coordinators over age 21 and volunteer promoters of both sexes aged 16-20 in urban/marginal communities. Promoters offer information to their peers and other youths in their local communities, distribute barrier contraceptives, and channel medical, psychological, and legal services to young people in need. Program procedure is described.

  1. Initial temperature distribution in Los Humeros, Mexico, geothermal field; Distribucion de temperatura inicial en el campo geotermico de Los Humeros, Puebla

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, A; Arellano, V; Aragon, A; Barragan, R.M; Izquierdo, G [Instituto de Investigaciones Electricas, Temixco, Morelos (Mexico); Pizano, A [Comision federal de Electricidad, Los Humeros, Puebla (Mexico)

    2000-12-01

    The initial formation temperatures surrounding 40 wells from the Los Humeros geothermal field are presented. These temperatures were estimated using the Horner and the sphere methods. A brief discussion on the applicability of each method is presented and previous applications are detailed. Then the more likely reservoir temperature of each well versus elevation is plotted based on the estimations about the main feed zone and the temperature of each well. The boiling with depth curve for pure water is also included. Two longitudinal and one traverse geological sections are presented to illustrate the field initial temperature distribution, the lithology and layers thickness, the basement topography and the wells traversed along each sections. Also, the main feed zones of the wells are indicated. Finally, the last series of measured temperature logs in well H-26 are produced by numerical simulation. This considers the well circulation losses and an assumed initial temperature profile. This profile iteratively modified until the computed profiles match the measured temperature profiles. The last assumed temperature profile is then considered as the best approximation to the undisturbed formation temperature around well H-26 and it is then compared with the stabilized temperatures obtained via the Horner and Sphere methods. [Spanish] Se presentan las temperaturas iniciales o estabilizadas de la formacion circundante a 40 pozos del campo geotermico Los Humeros, las cuales se estimaron mediante los metodos de Horner y el metodo de la esfera. Se presenta una discusion sobre la aplicacion de cada metodo y se detallan las aplicaciones previas del metodo de la esfera. Posteriormente y con base en las estimaciones de las principales zonas de aporte de cada pozo y sus correspondientes temperaturas se grafican las temperaturas mas probables de yacimiento para cada pozo contra la elevacion y se incluye en la misma grafica la curva de ebullicion del agua contra la elevacion. Se

  2. Mobile exhibition in Mexico

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1960-04-15

    Since January this year, a mobile atomic energy exhibition has been touring the principal cities of Mexico. In organizing this exhibition, the National Nuclear Energy Commission of Mexico was assisted by the International Atomic Energy Agency which has placed its second mobile radioisotope laboratory at the disposal of the Mexican authorities. In many States of the Republic, the visit of the mobile laboratory has given a powerful impetus to atomic training and research. Universities have made use of the laboratory for the training of young scientists in the basic isotope techniques. As a sequel to the work initiated with its aid, some universities are planning to start regular training courses in this field. The laboratory, which is a gift to the Agency from the United States, has been put to its first assignment in Mexico. It will shortly be sent to Argentina for a period of six months for use in training courses. IAEA's first mobile radioisotope unit, also donated by the United States, has been used for training purposes in Austria, the Federal Republic of Germany, Greece and Yugoslavia, and has now been sent to the Far East

  3. Mobile exhibition in Mexico

    International Nuclear Information System (INIS)

    1960-01-01

    Since January this year, a mobile atomic energy exhibition has been touring the principal cities of Mexico. In organizing this exhibition, the National Nuclear Energy Commission of Mexico was assisted by the International Atomic Energy Agency which has placed its second mobile radioisotope laboratory at the disposal of the Mexican authorities. In many States of the Republic, the visit of the mobile laboratory has given a powerful impetus to atomic training and research. Universities have made use of the laboratory for the training of young scientists in the basic isotope techniques. As a sequel to the work initiated with its aid, some universities are planning to start regular training courses in this field. The laboratory, which is a gift to the Agency from the United States, has been put to its first assignment in Mexico. It will shortly be sent to Argentina for a period of six months for use in training courses. IAEA's first mobile radioisotope unit, also donated by the United States, has been used for training purposes in Austria, the Federal Republic of Germany, Greece and Yugoslavia, and has now been sent to the Far East

  4. Report of the Inaugural Meeting of the TFOS i(2) = initiating innovation Series: Targeting the Unmet Need for Dry Eye Treatment.

    Science.gov (United States)

    Chao, Wendy; Belmonte, Carlos; Benitez Del Castillo, José M; Bron, Anthony J; Dua, Harminder S; Nichols, Kelly K; Novack, Gary D; Schrader, Stefan; Willcox, Mark D; Wolffsohn, James S; Sullivan, David A

    2016-04-01

    On March 21, 2015, a meeting was held in London, United Kingdom, to address the progress in targeting the unmet need for dry eye disease (DED) treatment. The meeting, which launched the i(2) = initiating innovation series, was sponsored by the Tear Film & Ocular Surface Society (TFOS; www.TearFilm.org) and supported by Dompé. The TFOS i(2) meeting was designed to review advances in the understanding of DED since publication of the 2007 TFOS International Dry Eye WorkShop (DEWS) report, and to help launch the highly anticipated sequel, DEWS II. The meeting was structured to discuss the scope of the DED problem, to review the clinical challenges of DED, and to consider the treatment challenges of DED. This article provides a synopsis of the presentations of this TFOS i(2) meeting. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Human NK cells selective targeting of colon cancer-initiating cells: A role for natural cytotoxicity receptors and MHC class i molecules

    KAUST Repository

    Tallerico, Rossana

    2013-01-23

    Tumor cell populations have been recently proposed to be composed of two compartments: tumor-initiating cells characterized by a slow and asymmetrical growth, and the "differentiated" cancer cells with a fast and symmetrical growth. Cancer stem cells or cancer-initiating cells (CICs) play a crucial role in tumor recurrence. The resistance of CICs to drugs and irradiation often allows them to survive traditional therapy. NK cells are potent cytotoxic lymphocytes that can recognize tumor cells. In this study, we have analyzed the NK cell recognition of tumor target cells derived from the two cancer cell compartments of colon adenocarcinoma lesions. Our data demonstrate that freshly purified allogeneic NK cells can recognize and kill colorectal carcinoma- derived CICs whereas the non-CIC counterpart of the tumors (differentiated tumor cells), either autologous or allogeneic, is less susceptible to NK cells. This difference in the NK cell susceptibility correlates with higher expression on CICs of ligands for NKp30 and NKp44 in the natural cytotoxicity receptor (NCR) group of activating NK receptors. In contrast, CICs express lower levels of MHC class I, known to inhibit NK recognition, on their surface than do the "differentiated" tumor cells. These data have been validated by confocal microscopy where NCR ligands and MHC class I molecule membrane distribution have been analyzed. Moreover, NK cell receptor blockade in cytotoxicity assays demonstrates that NCRs play a major role in the recognition of CIC targets. This study strengthens the idea that biology-based therapy harnessing NK cells could be an attractive opportunity in solid tumors. Copyright © 2013 by The American Association of Immunologists, Inc. All rights reserved.

  6. Human NK cells selective targeting of colon cancer-initiating cells: A role for natural cytotoxicity receptors and MHC class i molecules

    KAUST Repository

    Tallerico, Rossana; Todaro, Matilde; Di Franco, Simone; MacCalli, Cristina; Garofalo, Cinzia; Sottile, Rosa; Palmieri, Camillo; Tirinato, Luca; Pangigadde, Pradeepa N.; La Rocca, Rosanna; Mandelboim, Ofer; Stassi, Giorgio; Di Fabrizio, Enzo M.; Parmiani, Giorgio; Moretta, Alessandro; Dieli, Francesco; Kã rre, Klas; Carbone, Ennio

    2013-01-01

    Tumor cell populations have been recently proposed to be composed of two compartments: tumor-initiating cells characterized by a slow and asymmetrical growth, and the "differentiated" cancer cells with a fast and symmetrical growth. Cancer stem cells or cancer-initiating cells (CICs) play a crucial role in tumor recurrence. The resistance of CICs to drugs and irradiation often allows them to survive traditional therapy. NK cells are potent cytotoxic lymphocytes that can recognize tumor cells. In this study, we have analyzed the NK cell recognition of tumor target cells derived from the two cancer cell compartments of colon adenocarcinoma lesions. Our data demonstrate that freshly purified allogeneic NK cells can recognize and kill colorectal carcinoma- derived CICs whereas the non-CIC counterpart of the tumors (differentiated tumor cells), either autologous or allogeneic, is less susceptible to NK cells. This difference in the NK cell susceptibility correlates with higher expression on CICs of ligands for NKp30 and NKp44 in the natural cytotoxicity receptor (NCR) group of activating NK receptors. In contrast, CICs express lower levels of MHC class I, known to inhibit NK recognition, on their surface than do the "differentiated" tumor cells. These data have been validated by confocal microscopy where NCR ligands and MHC class I molecule membrane distribution have been analyzed. Moreover, NK cell receptor blockade in cytotoxicity assays demonstrates that NCRs play a major role in the recognition of CIC targets. This study strengthens the idea that biology-based therapy harnessing NK cells could be an attractive opportunity in solid tumors. Copyright © 2013 by The American Association of Immunologists, Inc. All rights reserved.

  7. Establishment and Application of a High Throughput Screening System Targeting the Interaction between HCV Internal Ribosome Entry Site and Human Eukaryotic Translation Initiation Factor 3

    Directory of Open Access Journals (Sweden)

    Yuying Zhu

    2017-05-01

    Full Text Available Viruses are intracellular obligate parasites and the host cellular machinery is usually recruited for their replication. Human eukaryotic translation initiation factor 3 (eIF3 could be directly recruited by the hepatitis C virus (HCV internal ribosome entry site (IRES to promote the translation of viral proteins. In this study, we establish a fluorescence polarization (FP based high throughput screening (HTS system targeting the interaction between HCV IRES and eIF3. By screening a total of 894 compounds with this HTS system, two compounds (Mucl39526 and NP39 are found to disturb the interaction between HCV IRES and eIF3. And these two compounds are further demonstrated to inhibit the HCV IRES-dependent translation in vitro. Thus, this HTS system is functional to screen the potential HCV replication inhibitors targeting human eIF3, which is helpful to overcome the problem of viral resistance. Surprisingly, one compound HP-3, a kind of oxytocin antagonist, is discovered to significantly enhance the interaction between HCV IRES and eIF3 by this HTS system. HP-3 is demonstrated to directly interact with HCV IRES and promote the HCV IRES-dependent translation both in vitro and in vivo, which strongly suggests that HP-3 has potentials to promote HCV replication. Therefore, this HTS system is also useful to screen the potential HCV replication enhancers, which is meaningful for understanding the viral replication and screening novel antiviral drugs. To our knowledge, this is the first HTS system targeting the interaction between eIF3 and HCV IRES, which could be applied to screen both potential HCV replication inhibitors and enhancers.

  8. September 1985 Mexico City, Mexico Images

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The magnitude 8.1 earthquake occurred off the Pacific coast of Mexico. The damage was concentrated in a 25 square km area of Mexico City, 350 km from the epicenter....

  9. Mexico and the 21st Century Power Partnership (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2015-02-01

    The 21st Century Power Partnership's program in Mexico (21CPP Mexico) is one initiative of the Clean Energy Ministerial, carried out in cooperation with government and local stakeholders, drawing upon an international community of power system expertise. The overall goal of this program is to support Mexico's power system transformation by accelerating the transition to a reliable, financially robust, and low-carbon system. 21CPP Mexico activities focus on achieving positive outcomes for all participants, especially addressing critical questions and challenges facing policymakers, regulators, and system operators. In support of this goal, 21CPP Mexico taps into deep networks of expertise and professional connections.

  10. Opportunity for America: Mexico`s coal future

    Energy Technology Data Exchange (ETDEWEB)

    Loose, V.W.

    1993-09-01

    This study examines the history, current status and future prospects for increased coal use in Mexico. Environmental implications of the power-generation capacity expansion plans are examined in general terms. Mexican environmental law and regulations are briefly reviewed along with the new sense of urgency in the cleanup of existing environmental problems and avoidance of new problems as clearly mandated in recent Mexican government policy initiatives. It is expected that new capital facilities will need to incorporate the latest in process and technology to comply with existing environmental regulation. Technology developments which address these issues are identified. What opportunities have new initiatives caused by the recent diversification of Mexico`s energy economy offered US firms? This report looks at the potential future use of coal in the Mexican energy economy, examining this issue with an eye toward identifying markets that might be available to US coal producers and the best way to approach them. Market opportunities are identified by examining new developments in the Mexican economy generally and the energy economy particularly. These developments are examined in light of the current situation and the history which brought Mexico to its present status.

  11. Mexico; Mexique

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-06-01

    This document summarizes the key energy data for Mexico: 1 - energy organizations and policy: Ministry of energy (SENER), Comision Reguladora de Energia (CRE), Ministry of Finances, Ministry of trade and industrial development (SECOFI), national commission for energy savings (CONAE); 2 - companies: federal commission of electricity (CFE), Minera Carbonifera Rio Escondido (MICARE - coal), Pemex (petroleum); 3 - energy production: resources, electric power, petroleum, natural gas; 4 - energy consumption; 5 - stakes and perspectives. Some economic and energy indicators are summarized in a series of tables: general indicators, supply indicators (reserves, refining and electric capacity, energy production, foreign trade), demand indicators (consumption trends, end use, energy independence, energy efficiency, CO{sub 2} emissions), energy status per year and per energy source. (J.S.)

  12. Eukaryotic initiation factor 2α--a downstream effector of mammalian target of rapamycin--modulates DNA repair and cancer response to treatment.

    Directory of Open Access Journals (Sweden)

    Liron Tuval-Kochen

    Full Text Available In an effort to circumvent resistance to rapamycin--an mTOR inhibitor--we searched for novel rapamycin-downstream-targets that may be key players in the response of cancer cells to therapy. We found that rapamycin, at nM concentrations, increased phosphorylation of eukaryotic initiation factor (eIF 2α in rapamycin-sensitive and estrogen-dependent MCF-7 cells, but had only a minimal effect on eIF2α phosphorylation in the rapamycin-insensitive triple-negative MDA-MB-231 cells. Addition of salubrinal--an inhibitor of eIF2α dephosphorylation--decreased expression of a surface marker associated with capacity for self renewal, increased senescence and induced clonogenic cell death, suggesting that excessive phosphorylation of eIF2α is detrimental to the cells' survival. Treating cells with salubrinal enhanced radiation-induced increase in eIF2α phosphorylation and clonogenic death and showed that irradiated cells are more sensitive to increased eIF2α phosphorylation than non-irradiated ones. Similar to salubrinal--the phosphomimetic eIF2α variant--S51D--increased sensitivity to radiation, and both abrogated radiation-induced increase in breast cancer type 1 susceptibility gene, thus implicating enhanced phosphorylation of eIF2α in modulation of DNA repair. Indeed, salubrinal inhibited non-homologous end joining as well as homologous recombination repair of double strand breaks that were induced by I-SceI in green fluorescent protein reporter plasmids. In addition to its effect on radiation, salubrinal enhanced eIF2α phosphorylation and clonogenic death in response to the histone deacetylase inhibitor--vorinostat. Finally, the catalytic competitive inhibitor of mTOR--Ku-0063794--increased phosphorylation of eIF2α demonstrating further the involvement of mTOR activity in modulating eIF2α phosphorylation. These experiments suggest that excessive phosphorylation of eIF2α decreases survival of cancer cells; making eIF2α a worthy target for

  13. Rethinking Molecular Mimicry in Rheumatic Heart Disease andAutoimmune Myocarditis: Laminin, Collagen IV, CAR and B1AR as Initial Targets of Disease

    Directory of Open Access Journals (Sweden)

    Robert eRoot-Bernstein

    2014-08-01

    Full Text Available Rationale: Molecular mimicry theory (MMT suggests that epitope mimicry between pathogens and human proteins can activate autoimmune disease. Group A streptococci (GAS mimics human cardiac myosin in rheumatic heart disease (RHD and coxsackie viruses (CX mimic actin in autoimmune myocarditis (AM. But myosin and actin are immunologically inaccessible and unlikely initial targets. Extracellular cardiac proteins that mimic GAS and CX would be more likely.Objectives: To determine whether extracellular cardiac proteins such as coxsackie and adenovirus receptor (CAR, beta 1 adrenergic receptor (B1AR, CD55/DAF, laminin, and collagen IV mimic GAS, CX and/or cardiac myosin or actin. Methods: BLAST 2.0 and LALIGN searches of the UniProt protein database were employed to identify potential molecular mimics. Quantitative ELISA was used to measure antibody cross-reactivity. Measurements: Similarities were considered to be significant if a sequence contained at least 5 identical amino acids in 10. Antibodies were considered to be cross-reactive if the binding constant had a Kd less than 10-9 M. Main Results: GAS mimics laminin, CAR and myosin. CX mimics actin and collagen IV and B1AR. The similarity search results are mirrored by antibody cross-reactivities. Additionally, antibodies against laminin recognize antibodies against collagen IV; antibodies against actin recognize antibodies against myosin, and antibodies against GAS recognize antibodies against CX. Thus, there is both mimicry of extracellular proteins and antigenic complementarity between GAS-CX in RHD/AM.Conclusions: RHD/AM may be due to combined infections of GAS with CX localize at cardiomyocytes may produce a synergistic, hyperinflammatory response that cross-reacts with laminin, collagen IV, CAR and/or B1AR. Epitope drift shifts the immune response to myosin and actin after cardiomyocytes become damaged.

  14. EC-LEDS Mexico: Advancing Clean Energy Goals

    Energy Technology Data Exchange (ETDEWEB)

    2016-07-01

    EC-LEDS works with the government of Mexico to help meet its goals of reducing greenhouse gas emissions from the energy sector. The program targets specific, highly technical areas where Mexico has indicated the program can add value and make an impact.

  15. New Mexico Ghost Towns

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data provides locations and non-spatial attributes of many ghost towns in the State of New Mexico, compiled from various sources. Locations provided with...

  16. Comparison of Deep Brain Stimulation Lead Targeting Accuracy and Procedure Duration between 1.5- and 3-Tesla Interventional Magnetic Resonance Imaging Systems: An Initial 12-Month Experience.

    Science.gov (United States)

    Southwell, Derek G; Narvid, Jared A; Martin, Alastair J; Qasim, Salman E; Starr, Philip A; Larson, Paul S

    2016-01-01

    Interventional magnetic resonance imaging (iMRI) allows deep brain stimulator lead placement under general anesthesia. While the accuracy of lead targeting has been described for iMRI systems utilizing 1.5-tesla magnets, a similar assessment of 3-tesla iMRI procedures has not been performed. To compare targeting accuracy, the number of lead targeting attempts, and surgical duration between procedures performed on 1.5- and 3-tesla iMRI systems. Radial targeting error, the number of targeting attempts, and procedure duration were compared between surgeries performed on 1.5- and 3-tesla iMRI systems (SmartFrame and ClearPoint systems). During the first year of operation of each system, 26 consecutive leads were implanted using the 1.5-tesla system, and 23 consecutive leads were implanted using the 3-tesla system. There was no significant difference in radial error (Mann-Whitney test, p = 0.26), number of lead placements that required multiple targeting attempts (Fisher's exact test, p = 0.59), or bilateral procedure durations between surgeries performed with the two systems (p = 0.15). Accurate DBS lead targeting can be achieved with iMRI systems utilizing either 1.5- or 3-tesla magnets. The use of a 3-tesla magnet, however, offers improved visualization of the target structures and allows comparable accuracy and efficiency of placement at the selected targets. © 2016 S. Karger AG, Basel.

  17. English Teaching in Mexico.

    Science.gov (United States)

    Salazar, Denise

    2002-01-01

    Discusses teaching English in Mexico, a country with important social, cultural, and economic ties to the United States. Looks at the various English teaching situations as well as teacher education for teachers in Mexico. Concludes that the English teaching situation in Mexico reflects great diversity and growth, and that the knowledge of English…

  18. Psychology in Mexico

    Science.gov (United States)

    Ruiz, Eleonora Rubio

    2011-01-01

    The first formal psychology course taught in Mexico was in 1896 at Mexico's National University; today, National Autonomous University of Mexico (UNAM in Spanish). The modern psychology from Europe and the US in the late 19th century were the primary influences of Mexican psychology, as well as psychoanalysis and both clinical and experimental…

  19. Relations between Mexico and the European Community

    Directory of Open Access Journals (Sweden)

    Pilar Alonso

    1992-12-01

    Full Text Available Mexico-EC bilateral relations must be considered within the general relation ECLatin America which -as the author remarks, do not appear among EC's preferential relations.Latin America can benefit from the Generalized Preference System which is not discriminatory, without reciprocity and generalized, but has some restrictions: for some products as textile, leather or oil. This affects some Latin American countries and specifically Mexico.Mexico initiates its relation with the EC in 1960; in 1975 both parts sign the Agreement on Economic and Trade Cooperation which has been substituted by the new General Agreement on Cooperation signed on April26, 1991. A new factor that will condition this relation is the Free Trade Agreement recently signed between USA, Canada and Mexico.

  20. Old age pensions in Mexico: Toward universal coverage

    OpenAIRE

    Willmore, Larry

    2014-01-01

    This paper chronicles the rise of social pensions in Mexico. First it summarizes the pension system prior to introduction of social pensions. Next it describes how Mexico City, the federal government, and seventeen of Mexico’s 31 states initiated social pensions, a policy supported eventually by each of the three major political parties. It concludes with thoughts on what remains to be done.

  1. The co registration of initial PET on the CT-radiotherapy reduces significantly the variabilities of anatomo-clinical target volume in the child hodgkin disease

    International Nuclear Information System (INIS)

    Metwally, H.; Blouet, A.; David, I.; Rives, M.; Izar, F.; Courbon, F.; Filleron, T.; Laprie, A.; Plat, G.; Vial, J.

    2009-01-01

    It exists a great interobserver variability for the anatomo-clinical target volume (C.T.V.) definition in children suffering of Hodgkin disease. In this study, the co-registration of the PET with F.D.G. on the planning computed tomography has significantly lead to a greater coherence in the clinical target volume definition. (N.C.)

  2. Priority setting for bird conservation in Mexico: the role of the Important Bird Areas program

    Science.gov (United States)

    Ma. del Coro Arizmendi; Laura Marquez Valdelamar; Humberto Berlanga

    2005-01-01

    Many species in Mexico are threatened and in need of protection. At least seventy species are considered to be globally threatened, yet conservation actions have been scarce and not coordinated. In 1996 BirdLife International’s Important Bird Areas Program was initiated in Mexico to identify a network of the most important places in Mexico for birds, with the...

  3. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Chino Mine in Silver City, New Mexico. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Kiatreungwattana, K.; Geiger, J.; Healey, V.; Mosey, G.

    2013-04-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Chino Mine site in Silver City, New Mexico, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  4. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Peru Mill Industrial Park in the City of Deming, New Mexico. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Kiatreungwattana, K.; Geiger, J.; Healey, V.; Mosey, G.

    2013-04-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Peru Mill Industrial Park site in the City of Deming, New Mexico, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  5. Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative

    NARCIS (Netherlands)

    Cuppens, T.; Annibali, D.; Coosemans, A.; Trovik, J.; Haar, N. Ter; Colas, E.; Garcia-Jimenez, A.; Vijver, K. van der; Kruitwagen, R.P.; Brinkhuis, M.; Zikan, M.; Dundr, P.; Huvila, J.; Carpen, O.; Haybaeck, J.; Moinfar, F.; Salvesen, H.B.; Stukan, M.; Mestdagh, C.; Zweemer, R.P.; Massuger, L.F.A.G.; Mallmann, M.R.; Wardelmann, E.; Mints, M.; Verbist, G.; Thomas, D; Gomme, E.; Hermans, E; Moerman, P.; Bosse, T.; Amant, F.

    2017-01-01

    Purpose: Uterine sarcomas are rare and heterogeneous tumors characterized by an aggressive clinical behavior. Their high rates of recurrence and mortality point to the urgent need for novel targeted therapies and alternative treatment strategies. However, no molecular prognostic or predictive

  6. Enhancing mTOR-targeted cancer therapy by preventing mTOR/raptor inhibition-initiated, mTOR/rictor-independent Akt activation

    OpenAIRE

    Wang, Xuerong; Yue, Ping; Kim, Young Ae; Fu, Haian; Khuri, Fadlo R.; Sun, Shi-Yong

    2008-01-01

    It has been shown that mTOR inhibitors activate Akt while inhibiting mTOR signaling. However, the underlying mechanisms and the impact of the Akt activation on mTOR-targeted cancer therapy are unclear. The present work focused on addressing the role of mTOR/rictor in mTOR inhibitor-induced Akt activation and the impact of sustained Akt activation on mTOR-targeted cancer therapy. Thus, we have demonstrated that mTOR inhibitors increase Akt phosphorylation through a mechanism independent of mTO...

  7. Impact of a universal intervention targeting childhood disruptive behavior problems on tobacco and alcohol initiation from age 10 to 13 years

    NARCIS (Netherlands)

    van Lier, P.A.C.; Huizink, A.C.; Crijnen, A.A.M.

    2008-01-01

    The distal impact of a school based universal preventive intervention targeting disruptive behavior problems on tobacco and alcohol use from age 10 to 13 years was explored. Second grade classrooms (children aged 7 years) were randomly assigned to the intervention or a control condition. Tobacco and

  8. Impact of a preventive intervention targeting childhood disruptive behavior problems on tobacco and alcohol initiation from age 10 to 13 years

    NARCIS (Netherlands)

    van Lier, P.A.C.; Huizink, A.; Crijnen, A.A.

    2009-01-01

    The distal impact of a school based universal preventive intervention targeting disruptive behavior problems on tobacco and alcohol use from age 10 to 13 years was explored. Second grade classrooms (children aged 7 years) were randomly assigned to the intervention or a control condition. Tobacco and

  9. Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers: Results from the Initial Screening Round of the IMPACT Study

    NARCIS (Netherlands)

    Bancroft, Elizabeth K.; Page, Elizabeth C.; Castro, Elena; Lilja, Hans; Vickers, Andrew; Sjoberg, Daniel; Assel, Melissa; Foster, Christopher S.; Mitchell, Gillian; Drew, Kate; Mæhle, Lovise; Axcrona, Karol; Evans, D. Gareth; Bulman, Barbara; Eccles, Diana; McBride, Donna; van Asperen, Christi; Vasen, Hans; Kiemeney, Lambertus A.; Ringelberg, Janneke; Cybulski, Cezary; Wokolorczyk, Dominika; Selkirk, Christina; Hulick, Peter J.; Bojesen, Anders; Skytte, Anne-Bine; Lam, Jimmy; Taylor, Louise; Oldenburg, Rogier; Cremers, Ruben; Verhaegh, Gerald; van Zelst-Stams, Wendy A.; Oosterwijk, Jan C.; Blanco, Ignacio; Salinas, Monica; Cook, Jackie; Rosario, Derek J.; Buys, Saundra; Conner, Tom; Ausems, Margreet G.; Ong, Kai-Ren; Hoffman, Jonathan; Domchek, Susan; Powers, Jacquelyn; Teixeira, Manuel R.; Maia, Sofia; Foulkes, William D.; Taherian, Nassim; Ruijs, Marielle; van Os, Theo

    2014-01-01

    Background: Men with germline breast cancer 1, early onset (BRCA1) or breast cancer 2, early onset (BRCA2) gene mutations have a higher risk of developing prostate cancer (PCa) than noncarriers. IMPACT (Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted screening in

  10. Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers : Results from the Initial Screening Round of the IMPACT Study

    NARCIS (Netherlands)

    Bancroft, Elizabeth K.; Page, Elizabeth C.; Castro, Elena; Lilja, Hans; Vickers, Andrew; Sjoberg, Daniel; Assel, Melissa; Foster, Christopher S.; Mitchell, Gillian; Drew, Kate; Maehle, Lovise; Axcrona, Karol; Evans, D. Gareth; Bulman, Barbara; Eccles, Diana; McBride, Donna; van Asperen, Christi; Vasen, Hans; Kiemeney, Lambertus A.; Ringelberg, Janneke; Cybulski, Cezary; Wokolorczyk, Dominika; Selkirk, Christina; Hulick, Peter J.; Bojesen, Anders; Skytte, Anne-Bine; Lam, Jimmy; Taylor, Louise; Oldenburg, Rogier; Cremers, Ruben; Verhaegh, Gerald; van Zelst-Stams, Wendy A.; Oosterwijk, Jan C.; Blanco, Ignacio; Salinas, Monica; Cook, Jackie; Rosario, Derek J.; Buys, Saundra; Conner, Tom; Ausems, Margreet G.; Ong, Kai-ren; Hoffman, Jonathan; Domchek, Susan; Powers, Jacquelyn; Teixeira, Manuel R.; Maia, Sofia; Foulkes, William D.; Taherian, Nassim; Ruijs, Marielle; Helderman-van den Enden, Apollonia T.

    Background: Men with germline breast cancer 1, early onset (BRCA1) or breast cancer 2, early onset (BRCA2) gene mutations have a higher risk of developing prostate cancer (PCa) than noncarriers. IMPACT (Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted screening in

  11. Mexico-Canada Knowledge Translation Partnership | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    This project will strengthen the capacity of INSP to promote evidence-informed decision making in Mexico through the adoption of selected tools and methods from the CHSRF and other related international initiatives. Specifically, an experienced senior program officer from CHSRF will spend two years with the Institute as ...

  12. Transcription factor HIF1A: downstream targets, associated pathways, polymorphic hypoxia response element (HRE) sites, and initiative for standardization of reporting in scientific literature.

    Science.gov (United States)

    Slemc, Lucija; Kunej, Tanja

    2016-11-01

    Hypoxia-inducible factor-1α (HIF-1α) has crucial role in adapting cells to hypoxia through expression regulation of many genes. Identification of HIF-1α target genes (HIF-1α-TGs) is important for understanding the adapting mechanism. The aim of the present study was to collect known HIF-1α-TGs and identify their associated pathways. Targets and associated genomics data were retrieved using PubMed, WoS ( http://apps.webofknowledge.com/ ), HGNC ( http://www.genenames.org/ ), NCBI ( http://www.ncbi.nlm.nih.gov/ ), Ensemblv.84 ( http://www.ensembl.org/index.html ), DAVID Bioinformatics Resources ( https://david.ncifcrf.gov /), and Disease Ontology database ( http://disease-ontology.org/ ). From 51 papers, we collected 98 HIF-1α TGs found to be associated with 20 pathways, including metabolism of carbohydrates and pathways in cancer. Reanalysis of genomic coordinates of published HREs (hypoxia response elements) revealed six polymorphisms within HRE sites (HRE-SNPs): ABCG2, ACE, CA9, and CP. Due to large heterogeneity of results presentation in scientific literature, we also propose a first step towards reporting standardization of HIF-1α-target interactions consisting of ten relevant data types. Suggested minimal checklist for reporting will enable faster development of a complete catalog of HIF-1α-TGs, data sharing, bioinformatics analyses, and setting novel more targeted hypotheses. The proposed format for data standardization is not yet complete but presents a baseline for further optimization of the protocol with additional details, for example, regarding the experimental validation.

  13. Mexico: perspectives in school health.

    Science.gov (United States)

    Allensworth, D M; Greene, A G

    1990-09-01

    The school health program in Mexico, directed by the Office of School Hygiene (la Unidad de Higiene Escolar), is in a state of flux. The program will change substantially if an initiative between the national offices of health and education is enacted. The initiative would establish a national commission to be replicated at state, county, and district levels. Commissions would oversee integration of the health services component, social participation, and research into the school health program which currently only focuses on health instruction and a healthy school environment. The initiative would restore and improve a former model that incorporated health services as a part of the school health program. The history of the school health program, which can trace its roots to 1861 and President Benito Juarez, is provided.

  14. Factors associated with cognitive function in older adults in Mexico

    Directory of Open Access Journals (Sweden)

    Jenny Miu

    2016-03-01

    Full Text Available Background: As populations age, cognitive decline and dementia pose significant burdens for societies and health care systems, including low- and middle-income countries such as Mexico. Minor age-related declines in cognitive function appear to represent a stable but heterogeneous phase in the continuum between normal cognitive ageing and dementia. Loss of cognitive function has impacts at societal and individual levels and understanding the risk factors can help provide a framework for health policies and interventions to target at-risk groups. Design: A cohort of older Mexican adults (50+ from the World Health Organization's Study on global AGEing and adult health (WHO SAGE was used to examine cognitive function, including a total of 2315 respondents, with 325 respondents aged 80 years and older. Cognition was objectively evaluated using verbal recall, verbal fluency, forward digit span and backward digit span, with differences in an overall cognitive score assessed against sociodemographic variables, and associated factors using linear regression. Results: The most significant predictors of poorer cognitive function were found to be older age (β=−13.88, rural living (β=−2.25, low income (β=−8.28, self-reported severe or extreme memory difficulties (β=−6.62, and difficulty with two or more activities of daily living (β=−2.02. Conclusions: These findings can inform public health initiatives to address cognitive impairment in ageing populations in Mexico and other middle-income countries.

  15. [Aging in Mexico].

    Science.gov (United States)

    Contreras de Lehr, E

    1986-01-01

    Demographic social and economic aspects of the situation of the elderly in Mexico are described with special emphasis upon education programmes and types of care in nursing homes. Considering the future trends of an increase in Mexico's elderly population, the author calls for more efforts in research and training in the field of gerontology. First results in this area are reported.

  16. 78 FR 29325 - Prestressed Concrete Steel Rail Tie Wire From Mexico, the People's Republic of China, and...

    Science.gov (United States)

    2013-05-20

    ...] Prestressed Concrete Steel Rail Tie Wire From Mexico, the People's Republic of China, and Thailand: Initiation... of prestressed concrete steel rail tie wire (``PC tie wire'') from Mexico, the PRC, and Thailand... Prestressed Concrete Steel Rail Tie Wire from the PRC, Mexico, and Thailand, filed on April 23, 2013 (the...

  17. 78 FR 57619 - Prestressed Concrete Steel Rail Tie Wire From Mexico, Thailand, and the People's Republic of...

    Science.gov (United States)

    2013-09-19

    ...] Prestressed Concrete Steel Rail Tie Wire From Mexico, Thailand, and the People's Republic of China... prestressed concrete steel rail tie wire from Mexico, Thailand, and the People's Republic of China. See Prestressed Concrete Steel Rail Tie Wire From Mexico, the People's Republic of China, and Thailand: Initiation...

  18. Different target-discrimination times can be followed by the same saccade-initiation timing in different stimulus conditions during visual searches

    Science.gov (United States)

    Tanaka, Tomohiro; Nishida, Satoshi

    2015-01-01

    The neuronal processes that underlie visual searches can be divided into two stages: target discrimination and saccade preparation/generation. This predicts that the length of time of the prediscrimination stage varies according to the search difficulty across different stimulus conditions, whereas the length of the latter postdiscrimination stage is stimulus invariant. However, recent studies have suggested that the length of the postdiscrimination interval changes with different stimulus conditions. To address whether and how the visual stimulus affects determination of the postdiscrimination interval, we recorded single-neuron activity in the lateral intraparietal area (LIP) when monkeys (Macaca fuscata) performed a color-singleton search involving four stimulus conditions that differed regarding luminance (Bright vs. Dim) and target-distractor color similarity (Easy vs. Difficult). We specifically focused on comparing activities between the Bright-Difficult and Dim-Easy conditions, in which the visual stimuli were considerably different, but the mean reaction times were indistinguishable. This allowed us to examine the neuronal activity when the difference in the degree of search speed between different stimulus conditions was minimal. We found that not only prediscrimination but also postdiscrimination intervals varied across stimulus conditions: the postdiscrimination interval was longer in the Dim-Easy condition than in the Bright-Difficult condition. Further analysis revealed that the postdiscrimination interval might vary with stimulus luminance. A computer simulation using an accumulation-to-threshold model suggested that the luminance-related difference in visual response strength at discrimination time could be the cause of different postdiscrimination intervals. PMID:25995344

  19. Energy, environment and development in Mexico

    International Nuclear Information System (INIS)

    Lohmann, J.

    1990-01-01

    Mexico is a country at the crossroads. It has huge potentials in energy, in natural resources and in human resources. It is currently experiencing one of the most serious crises in its history - economic, ecological, political - and it is making efforts to overcome the problems behind these crises, which may affect us all because of Mexico's importance as energy producer and energy consumer. Mexico is one of the developing countries which has participated actively in finding solutions to the worlds environmental problems not least the problem of climatic changes as a result of increasing energy consumption. Mexico is seeing the consequences at local and national level, and is taking steps to change course. At the same time, it has also expressed interest in participating in international initiatives and cooperation to solve these problem. But Mexico finds itself in a situation not unlike that of many East European countries after the fall of the communist regimes. The old system is tumbling, the will to change is present, but there is a lack of resources. 123 refs., 45 tabs

  20. Policies to reduce carbon emissions from Mexico

    International Nuclear Information System (INIS)

    Mendoza, Y.

    1991-01-01

    The two long-term scenarios carried out for Mexico attempt to paint a picture of carbon emissions and energy use in the year 2025. The scenarios reveal that Mexico's current energy path is not optimal; the energy-intensity indicators show an increasing reliance on petroleum products and electricity over the next 40 years. Thus, Mexico must embark on a program of energy conservation in the near future. Mexico recently has undertaken several energy conservation efforts. The Mexican government implemented a National Program for Energy Modernization. This program identifies the promotion of energy conservation in Mexico as one of its top priorities between 1990 and 1994. It incorporates a number of actions geared at improving energy conservation, including: establishing pricing policies which pay special attention to electricity tariffs; setting aside budget appropriations for energy-savings programs; carrying out an energy diagnosis in the transportation and industrial sectors; promoting cogeneration and new legislation in this field; setting efficiency standards for equipment; initiating a public education campaign to inform people about energy conservation; promoting the participation of research institutes and consulting firms in the research of the technological aspects of energy-saving measures; and creating agreement with industrial and commerce associations

  1. A target-driven collaborative care model for Major Depressive Disorder is effective in primary care in the Netherlands. A randomized clinical trial from the depression initiative.

    Science.gov (United States)

    Huijbregts, Klaas M L; de Jong, Fransina J; van Marwijk, Harm W J; Beekman, Aartjan T F; Adèr, Herman J; Hakkaart-van Roijen, Leona; Unützer, Jürgen; van der Feltz-Cornelis, Christina M

    2013-04-25

    Practice variation in the primary care treatment of depression may be considerable in the Netherlands, due to relatively small and unregulated practices. We adapted the collaborative care model for the treatment of Major Depressive Disorder (MDD) to accommodate existing practice variation and tested whether this had added value over Care as Usual (CAU). A cluster randomized controlled trial was conducted to compare an adapted target driven collaborative care model with Care as Usual (CAU). Randomization was at the level of 18 (sub)urban primary care centers. The care manager and GP were supported by a web-based tracking and decision aid system that advised targeted treatment actions to achieve rapid response and if possible remission, and that warned the consultant psychiatrist if such treatment advice was not followed up. Eligible patients had a score of 10 or higher on the PHQ9, and met diagnostic criteria for major depression at the subsequent MINI Neuropsychiatric interview. A total of 93 patients were identified by screening. They received either collaborative care (CC) or CAU. Another 56 patients received collaborative care after identification by the GP. The outcome measures were response to treatment (50% or greater reduction of the PHQ9-total score from baseline) at three, six, nine and twelve months, and remission (a score of 0-4 on the PHQ9 at follow-up). Treatment response and remission in CAU were low. Collaborative care was more effective on achieving treatment response than CAU at three months for the total group of patients who received collaborative care [OR 5.2 ((1.41-16.09), NNT 2] and at nine months [OR 5.6 ((1.40-22.58)), NNT 3]. The effect was not statistically significant at 6 and 12 months. A relatively high percentage of patients (36.5%) did not return one or more follow-up questionnaires. There was no evidence for selective non response. Our adapted target driven CC was considerably more effective than CAU for MDD in primary care in the

  2. Mexico and Central America.

    Science.gov (United States)

    Bronfman, M

    1998-01-01

    This article reviews the literature on migration and HIV/AIDS in Mexico and Central America, including Belize, Costa Rica, El Salvador, Guatemala, Honduras, Mexico, Nicaragua, and Panama. Most migrants travel to the US through Mexico. US-Mexico trade agreements created opportunities for increased risk of HIV transmission. The research literature focuses on Mexico. Most countries, with the exception of Belize and Costa Rica, are sending countries. Human rights of migrants are violated in transit and at destination. Migration policies determine migration processes. The Mexican-born population in the US is about 3% of US population and 8% of Mexico's population. About 22% arrived during 1992-97, and about 500,000 are naturalized US citizens. An additional 11 million have a Mexican ethnic background. Mexican migrants are usually economically active men who had jobs before leaving and were urban people who settled in California, Texas, Illinois, and Arizona. Most Mexican migrants enter illegally. Many return to Mexico. The main paths of HIV transmission are homosexual, heterosexual, and IV-drug-injecting persons. Latino migrants frequently use prostitutes, adopt new sexual practices including anal penetration among men, greater diversity of sexual partners, and use of injectable drugs.

  3. Paramedic Initiation of Neuroprotective Agent Infusions: Successful Achievement of Target Blood Levels and Attained Level Effect on Clinical Outcomes in the FAST-MAG Pivotal Trial (Field Administration of Stroke Therapy - Magnesium).

    Science.gov (United States)

    Shkirkova, Kristina; Starkman, Sidney; Sanossian, Nerses; Eckstein, Marc; Stratton, Samuel; Pratt, Frank; Conwit, Robin; Hamilton, Scott; Sharma, Latisha; Liebeskind, David; Restrepo, Lucas; Valdes-Sueiras, Miguel; Saver, Jeffrey L

    2017-07-01

    Paramedic use of fixed-size lumen, gravity-controlled tubing to initiate intravenous infusions in the field may allow rapid start of neuroprotective therapy for acute stroke. In a large, multicenter trial, we evaluated its efficacy in attaining target serum levels of candidate neuroprotective agent magnesium sulfate and the relation of achieved magnesium levels to outcome. The FAST-MAG phase 3 trial (Field Administration of Stroke Therapy - Magnesium) randomized 1700 patients within 2 hours of onset to paramedic-initiated, a 15-minute loading intravenous infusion of magnesium or placebo followed by a 24-hour maintenance dose. The drug delivery strategy included fixed-size lumen, gravity-controlled tubing for field drug administration, and a shrink-wrapped ambulance kit containing both the randomized field loading and hospital maintenance doses for seamless continuation. Among patient randomized to active treatment, magnesium levels in the first 72 hours were assessed 987 times in 572 patients. Mean patient age was 70 years (SD±14 years), and 45% were women. During the 24-hour period of active infusion, mean achieved serum level was 3.91 (±0.8), consistent with trial target. Mg levels were increased by older age, female sex, lower weight, height, body mass index, and estimated glomerular filtration rate, and higher blood urea nitrogen, hemoglobin, and higher hematocrit. Adjusted odds for clinical outcomes did not differ by achieved Mg level, including disability at 90 days, symptomatic hemorrhage, or death. Paramedic infusion initiation using gravity-controlled tubing permits rapid achievement of target serum levels of potential neuroprotective agents. The absence of association of clinical outcomes with achieved magnesium levels provides further evidence that magnesium is not biologically neuroprotective in acute stroke. © 2017 American Heart Association, Inc.

  4. Effects of Three Motivationally Targeted Mobile Device Applications on Initial Physical Activity and Sedentary Behavior Change in Midlife and Older Adults: A Randomized Trial.

    Directory of Open Access Journals (Sweden)

    Abby C King

    Full Text Available While there has been an explosion of mobile device applications (apps promoting healthful behaviors, including physical activity and sedentary patterns, surprisingly few have been based explicitly on strategies drawn from behavioral theory and evidence.This study provided an initial 8-week evaluation of three different customized physical activity-sedentary behavior apps drawn from conceptually distinct motivational frames in comparison with a commercially available control app.Ninety-five underactive adults ages 45 years and older with no prior smartphone experience were randomized to use an analytically framed app, a socially framed app, an affectively framed app, or a diet-tracker control app. Daily physical activity and sedentary behavior were measured using the smartphone's built-in accelerometer and daily self-report measures.Mixed-effects models indicated that, over the 8-week period, the social app users showed significantly greater overall increases in weekly accelerometry-derived moderate to vigorous physical activity relative to the other three arms (P values for between-arm differences = .04-.005; Social vs. Control app: d = 1.05, CI = 0.44,1.67; Social vs. Affect app: d = 0.89, CI = 0.27,1.51; Social vs. Analytic app: d = 0.89, CI = 0.27,1.51, while more variable responses were observed among users of the other two motivationally framed apps. Social app users also had significantly lower overall amounts of accelerometry-derived sedentary behavior relative to the other three arms (P values for between-arm differences = .02-.001; Social vs. Control app: d = 1.10,CI = 0.48,1.72; Social vs. Affect app: d = 0.94, CI = 0.32,1.56; Social vs. Analytic app: d = 1.24, CI = 0.59,1.89. Additionally, Social and Affect app users reported lower overall sitting time compared to the other two arms (P values for between-arm differences < .001; Social vs. Control app: d = 1.59,CI = 0.92, 2.25; Social vs. Analytic app: d = 1.89,CI = 1.17, 2.61; Affect

  5. Effects of Three Motivationally Targeted Mobile Device Applications on Initial Physical Activity and Sedentary Behavior Change in Midlife and Older Adults: A Randomized Trial.

    Science.gov (United States)

    King, Abby C; Hekler, Eric B; Grieco, Lauren A; Winter, Sandra J; Sheats, Jylana L; Buman, Matthew P; Banerjee, Banny; Robinson, Thomas N; Cirimele, Jesse

    2016-01-01

    While there has been an explosion of mobile device applications (apps) promoting healthful behaviors, including physical activity and sedentary patterns, surprisingly few have been based explicitly on strategies drawn from behavioral theory and evidence. This study provided an initial 8-week evaluation of three different customized physical activity-sedentary behavior apps drawn from conceptually distinct motivational frames in comparison with a commercially available control app. Ninety-five underactive adults ages 45 years and older with no prior smartphone experience were randomized to use an analytically framed app, a socially framed app, an affectively framed app, or a diet-tracker control app. Daily physical activity and sedentary behavior were measured using the smartphone's built-in accelerometer and daily self-report measures. Mixed-effects models indicated that, over the 8-week period, the social app users showed significantly greater overall increases in weekly accelerometry-derived moderate to vigorous physical activity relative to the other three arms (P values for between-arm differences = .04-.005; Social vs. Control app: d = 1.05, CI = 0.44,1.67; Social vs. Affect app: d = 0.89, CI = 0.27,1.51; Social vs. Analytic app: d = 0.89, CI = 0.27,1.51), while more variable responses were observed among users of the other two motivationally framed apps. Social app users also had significantly lower overall amounts of accelerometry-derived sedentary behavior relative to the other three arms (P values for between-arm differences = .02-.001; Social vs. Control app: d = 1.10,CI = 0.48,1.72; Social vs. Affect app: d = 0.94, CI = 0.32,1.56; Social vs. Analytic app: d = 1.24, CI = 0.59,1.89). Additionally, Social and Affect app users reported lower overall sitting time compared to the other two arms (P values for between-arm differences < .001; Social vs. Control app: d = 1.59,CI = 0.92, 2.25; Social vs. Analytic app: d = 1.89,CI = 1.17, 2.61; Affect vs. Control

  6. Mexico's nuclear paradox

    International Nuclear Information System (INIS)

    Redclift, M.

    1989-01-01

    Opposition to Mexico's nuclear reactors at Laguna Verde has grown during the last two years. The nuclear programme is blamed for being expensive and wasteful, and the decision to rely on the USA contradicts Mexico's espoused policy of greater independence from the USA. The way in which petroleum revenues were used to precipitate the nuclear option is compared with the lack of urgency given to renewable energy and greater energy efficiency. From a social and environmental perspective, as well as an economic one, Mexico's nuclear programme is judged expensive and irrelevant. (author)

  7. Supply-side interventions to improve health: Findings from the Salud Mesoamérica Initiative.

    Science.gov (United States)

    Mokdad, Ali H; Palmisano, Erin B; Zúñiga-Brenes, Paola; Ríos-Zertuche, Diego; Johanns, Casey K; Schaefer, Alexandra; Desai, Sima S; Haakenstad, Annie; Gagnier, Marielle C; McNellan, Claire R; Colombara, Danny V; López Romero, Sonia; Castillo, Leolin; Salvatierra, Benito; Hernandez, Bernardo; Betancourt-Cravioto, Miguel; Mujica-Rosales, Ricardo; Regalia, Ferdinando; Tapia-Conyer, Roberto; Iriarte, Emma

    2018-01-01

    Results-based aid (RBA) is increasingly used to incentivize action in health. In Mesoamerica, the region consisting of southern Mexico and Central America, the RBA project known as the Salud Mesoamérica Initiative (SMI) was designed to target disparities in maternal and child health, focusing on the poorest 20% of the population across the region. Data were first collected in 365 intervention health facilities to establish a baseline of indicators. For the first follow-up measure, 18 to 24 months later, 368 facilities were evaluated in these same areas. At both stages, we measured a near-identical set of supply-side performance indicators in line with country-specific priorities in maternal and child health. All countries showed progress in performance indicators, although with different levels. El Salvador, Honduras, Nicaragua, and Panama reached their 18-month targets, while the State of Chiapas in Mexico, Guatemala, and Belize did not. A second follow-up measurement in Chiapas and Guatemala showed continued progress, as they achieved previously missed targets nine to 12 months later, after implementing a performance improvement plan. Our findings show an initial success in the supply-side indicators of SMI. Our data suggest that the RBA approach can be a motivator to improve availability of drugs and services in poor areas. Moreover, our innovative monitoring and evaluation framework will allow health officials with limited resources to identify and target areas of greatest need.

  8. Translation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma

    Science.gov (United States)

    Stenson, Mary J.; Maurer, Matthew J.; Wellik, Linda E.; Link, Brian; Hege, Kristen; Dogan, Ahmet; Sotomayor, Eduardo; Witzig, Thomas; Gupta, Mamta

    2015-01-01

    Deregulated mRNA translation has been implicated in disease development and in part is controlled by a eukaryotic initiation complex eIF4F (composed of eIF4E, eIF4G and eIF4A). We demonstrate here that the cap bound fraction from lymphoma cells was enriched with eIF4G and eIF4E indicating that lymphoma cells exist in an activated translational state. Moreover, 77% (110/142) of diffuse large B cell lymphoma tumors expressed eIF4E and this was associated with an inferior event free survival. Over-expression of wild-type eIF4E (eIF4EWT) but not cap-mutant eIF4E (eIF4Ecap mutant) increased the activation of the eIF4F complex. Treatment with the active-site dual mTOR inhibitor CC214-1 reduced the level of the eIF4F complex by decreasing the cap bound fraction of eIF4G and increasing the levels of 4E-BP1. CC214-1 inhibited both the cap dependent and global protein translation. CC214-1 inhibited c-Myc, and cyclin D3 translation by decreasing polysomal fractions from lymphoma cells. Inhibition of eIF4E with shRNA further decreased the CC214-1 induced inhibition of the eIF4F complex, c-Myc, cyclin D3 translation, and colony formation. These studies demonstrate that the eIF4F complex is deregulated in aggressive lymphoma and that dual mTOR therapy has therapeutic potential in these patients. PMID:25839159

  9. Targeted inhibition of TGF-β results in an initial improvement but long-term deficit in force production after contraction-induced skeletal muscle injury.

    Science.gov (United States)

    Gumucio, Jonathan P; Flood, Michael D; Phan, Anthony C; Brooks, Susan V; Mendias, Christopher L

    2013-08-15

    Transforming growth factor-β (TGF-β) is a proinflammatory cytokine that regulates the response of many tissues following injury. Previous studies in our lab have shown that treating muscles with TGF-β results in a dramatic accumulation of type I collagen, substantial fiber atrophy, and a marked decrease in force production. Because TGF-β promotes atrophy and fibrosis, our objective was to investigate whether the inhibition of TGF-β after injury would enhance the recovery of muscle following injury. We hypothesized that inhibiting TGF-β after contraction-induced injury would improve the functional recovery of muscles by preventing muscle fiber atrophy and weakness, and by limiting the accumulation of fibrotic scar tissue. To test this hypothesis, we induced an injury using a series of in situ lengthening contractions to extensor digitorum longus muscles of mice treated with either a bioneutralizing antibody against TGF-β or a sham antibody. Compared with controls, muscles from mice receiving TGF-β inhibitor showed a greater recovery in force 3 days and 7 days after injury but had a decrease in force compared with controls at the 21-day time point. The early enhancement in force in the TGF-β inhibitor group was associated with an initial improvement in tissue morphology, but, at 21 days, while the control group was fully recovered, the TGF-β inhibitor group displayed an irregular extracellular matrix and an increase in atrogin-1 gene expression. These results indicate that the inhibition of TGF-β promotes the early recovery of muscle function but is detrimental overall to full muscle recovery following moderate to severe muscle injuries.

  10. Initiating NTD programs targeting schistosomiasis and soil-transmitted helminthiasis in two provinces of the Democratic Republic of the Congo: Establishment of baseline prevalence for mass drug administration.

    Science.gov (United States)

    Kabore, Achille; Ibikounle, Moudachirou; Tougoue, Jean Jacques; Mupoyi, Sylvain; Ndombe, Martin; Shannon, Scott; Ottesen, Eric A; Mukunda, Faustin; Awaca, Naomi

    2017-02-01

    prevalence of hookworm, roundworm and whipworm were 51.62% (32.40%-71.50%), 15.77% (0.50%-39.60%) and 13.46 (0.50%-33.20%), respectively. This study provided the evidence base for implementing programs targeting SCH and STH in these Health Zones. Observations also reinforce the operational value and feasibility of the POC-CCA test to detect S. mansoni and, for the first time, S. intercalatum infections in a routine NTD program setting. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. The paredon, Mexico, obsidian source and early formative exchange.

    Science.gov (United States)

    Charlton, T H; Grove, D C; Hopke, P K

    1978-09-01

    In 1975, archeological surface surveys of trade routes located again a pre-Hispanic obsidian source in central Mexico first reported in 1902. Initial trace element studies of the Paredón source through an analysis by neutron activation have been compared with similar studies of the obsidian found at Chalcatzingo 150 kilometers from the source. These comparisons indicate that obsidian from Paredón, rather than Otumba, was of primary importance during the Early Formative in central Mexico.

  12. Silencing criticism in Mexico

    Directory of Open Access Journals (Sweden)

    Ximena Suárez

    2017-10-01

    Full Text Available Journalists and human rights defenders in Mexico are being attacked in an attempt to silence their criticism. Many are forced to flee or risk being assassinated. The consequences are both personal and of wider social significance.

  13. New Mexico State Boundary

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The TIGER/Line Shapefiles are an extract of selected geographic and cartographic information from the Census MAF/TIGER database. The Census MAF/TIGER database...

  14. New Mexico Federal Lands

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This map layer consists of federally owned or administered lands of the United States, Puerto Rico, and the U.S. Virgin Islands. Only areas of 640 acres or more are...

  15. New Mexico Mountain Ranges

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The Geographic Names Information System (GNIS) actively seeks data from and partnerships with Government agencies at all levels and other interested organizations....

  16. Mexico - Surface Weather Observations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Mexican Surface Daily Observations taken at 94 observatories located throughout Mexico, beginning in 1872 and going up through 1981. The data resided on paper...

  17. About the RAS Initiative

    Science.gov (United States)

    The RAS Initiative, a "hub and spoke" model, connects researchers to better understand and target the more than 30% of cancers driven by mutations in RAS genes. Includes oversight and contact information.

  18. Mexico tornado climatology

    Directory of Open Access Journals (Sweden)

    Manuel Macías Medrano

    2013-07-01

    Full Text Available A brief introduction on some features of tornado database in Mexico is exposed showing its substantive criteria. We resent a brief analysis about main Mexican tornadoes´ characteristics, based on data collected between 2000 to 2010, talking about spatial and temporal expressions (historical, seasonal and horary in order to show the importance of it destruction capacity and also the people´s vulnerability in Mexico.

  19. Occupational health in Mexico.

    Science.gov (United States)

    Carreón, Tania; Santos-Burgoa, Carlos; Baron, Sherry; Hernández, Sendy

    2002-01-01

    The authors discuss the maquiladoras and child labor, and offer an overview of the history of occupational safety and health in Mexico that covers laws and regulations, social security, unions, and enforcement of legislation. The organization and structure of the various institutions responsible for occupational safety and health (OSH), as well as administrative procedures, are described. This article concludes with a list of the new challenges for OSH in Mexico.

  20. Initiative hard coal; Initiative Steinkohle

    Energy Technology Data Exchange (ETDEWEB)

    Leonhardt, J.

    2007-08-02

    In order to decrease the import dependence of hard coal in the European Union, the author has submitted suggestions to the director of conventional sources of energy (directorate general for energy and transport) of the European community, which found a positive resonance. These suggestions are summarized in an elaboration 'Initiative Hard Coal'. After clarifying the starting situation and defining the target the presupposition for a better use of hard coal deposits as raw material in the European Union are pointed out. On that basis concrete suggestions for measures are made. Apart from the conditions of the deposits it concerns thereby also new mining techniques and mining-economical developments, connected with tasks for the mining-machine industry. (orig.)

  1. Geothermal energy from deep sedimentary basins: The Valley of Mexico (Central Mexico)

    Science.gov (United States)

    Lenhardt, Nils; Götz, Annette E.

    2015-04-01

    The geothermal potential of the Valley of Mexico has not been addressed in the past, although volcaniclastic settings in other parts of the world contain promising target reservoir formations. A first assessment of the geothermal potential of the Valley of Mexico is based on thermophysical data gained from outcrop analogues, covering all lithofacies types, and evaluation of groundwater temperature and heat flow values from literature. Furthermore, the volumetric approach of Muffler and Cataldi (1978) leads to a first estimation of ca. 4000 TWh (14.4 EJ) of power generation from Neogene volcanic rocks within the Valley of Mexico. Comparison with data from other sedimentary basins where deep geothermal reservoirs are identified shows the high potential of the Valley of Mexico for future geothermal reservoir utilization. The mainly low permeable lithotypes may be operated as stimulated systems, depending on the fracture porosity in the deeper subsurface. In some areas also auto-convective thermal water circulation might be expected and direct heat use without artificial stimulation becomes reasonable. Thermophysical properties of tuffs and siliciclastic rocks qualify them as promising target horizons (Lenhardt and Götz, 2015). The here presented data serve to identify exploration areas and are valuable attributes for reservoir modelling, contributing to (1) a reliable reservoir prognosis, (2) the decision of potential reservoir stimulation, and (3) the planning of long-term efficient reservoir utilization. References Lenhardt, N., Götz, A.E., 2015. Geothermal reservoir potential of volcaniclastic settings: The Valley of Mexico, Central Mexico. Renewable Energy. [in press] Muffler, P., Cataldi, R., 1978. Methods for regional assessment of geothermal resources. Geothermics, 7, 53-89.

  2. Water Markets in Mexico: Opportunities and Constraints

    OpenAIRE

    Hearne, Robert R.; Trava, Jose L.

    1997-01-01

    In 1992, the Government of Mexico initiated a new national water law which decentralised water resources management and allowed the market transfer of water-use concessions between individual irrigators. These reforms were expected to improve water resources management through greater user participation in irrigation management, as well as to increase irrigators incentives to improve water-use efficiency. At the time of its proposal the 1992 Federal Water Law was considered to the first step ...

  3. INITIAL TRAINING OF RESEARCHERS

    Directory of Open Access Journals (Sweden)

    Karina Alejandra Cruz-Pallares

    2015-07-01

    Full Text Available The document presents results of a research that used as strategy a complementary training project with thirty-three students of a Bachelors Degree in Primary School 1997(DPS,1997 of an Education Faculty for the initial training of investigators, applied by four teachers members of the academic research group in Mexico; that develops through process of action research methodology. Highlighted in results is the strengthening of the competition of reading, understanding and writing scientific texts, which is analogous to the first feature of the graduate profile called intellectual skills. Among the conclusions it is emphasized that the initial training of teachers in a task that is quite interesting, challenging and complex, as is the educational complex phenomenon.

  4. New Mexico Property Tax Districts

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This layer represents boundaries for New Mexico tax district "OUT" categories and incorporated/municipal "IN" categories as identified on the "Certificate of Tax...

  5. New Mexico State Forestry Districts

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries of the New Mexico Forestry Districts, plus the names of the district offices. It is in a vector digital structure digitized from a...

  6. HSIP Hospitals in New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Hospitals in New Mexico The term "hospital" ... means an institution which- (1) is primarily engaged in providing, by or under the supervision of physicians, to...

  7. The economic impact of Sandia National Laboratories on central New Mexico and the state of New Mexico fiscal year 1997

    International Nuclear Information System (INIS)

    Lansford, R.R.; Nielsen, T.G.; Schultz, J.; Adcock, L.D.; Gentry, L.M.

    1998-01-01

    Sandia National Laboratories (SNL) was established in 1949 to perform the engineering development and ordnance responsibilities associated with nuclear weapons. By the early 1960's the facility had evolved into an engineering research and development laboratory and became a multiprogram laboratory during the 1970s. Sandia is operated for the US Department of Energy by the Sandia Corporation, a wholly-owned subsidiary of Lockheed Martin, Incorporated. For several years, the US Department of Energy (DOE) Albuquerque Operations Office (AL) and New Mexico State University (NMSU) have maintained an inter-industry, input-output model with capabilities to assess the impacts of developments initiated outside the economy such as federal DOE monies that flow into the state, on an economy. This model will be used to assess economic, personal income and employment impacts of SNL on central New Mexico and the state of New Mexico. For this report, the reference period is FY 1997 (October 1, 1996, through September 30, 1997) and includes two major impact analyses: the impact of SNL activities on central New Mexico and the economic impacts of SNL on the state of New Mexico. For purposes of this report, the central New Mexico region includes Bernalillo, Sandoval, Valencia, and Torrance counties. Total impact represents both direct and indirect respending by business, including induced effects (respending by households). The standard multipliers used in determining impacts results from the inter-industry, input-output models developed for the four-county region and the state of New Mexico. 6 figs., 10 tabs

  8. Teledermatology in Tijuana, Mexico.

    Science.gov (United States)

    Brown, Megan

    2016-12-01

    The Health Frontiers in Tijuana (HFiT) clinic is a binational partnership between the University of California, San Diego School of Medicine (San Diego, California); the Universidad Autónoma de Baja California School of Medicine (Tijuana, Mexico); and Desayunador Salesiano Padre Chava, a community grassroots organization in Tijuana, Mexico. Health Frontiers in Tijuana provides accessible quality health care for the underserved in Tijuana's Zona Norte. This article is a narrative meant to share my clinical experience as a dermatology resident who worked with HFiT to establish teledermatology services at this clinic.

  9. Mexico: a solar future

    International Nuclear Information System (INIS)

    2016-01-01

    Immersed in the global price instability of fossil fuels and with an upsurge in renewables as the agent for development, countries like Mexico, that largely depend on this resource to generate income and whose national electrical energy generation mainly comes from these fuels, find themselves obliged to take decisions that allow them to maintain their appeal compared to other emerging markets. In this decision-making process, Mexico has been slow to implement its long-awaited Energy Reform that incentivises direct foreign investment and avoids the monopolies that have until recently prevailed in the Mexican energy and electricity sector. (Author)

  10. Medical knowledge related to Rocky Mountain spotted fever in Sonora, Mexico.

    Science.gov (United States)

    Alvarez-Hernandez, Gerardo; Ernst, Kacey; Acuña-Melendrez, Natalia Haydee; Vargas-Ortega, Anabel Patricia; Candia-Plata, Maria Del Carmen

    2018-03-01

    Rocky Mountain spotted fever (RMSF) is a tick-borne disease with a high case-fatality rate unless diagnosed promptly and treated timely with doxycycline. Physician knowledge about presentation and treatment can improve outcomes of RMSF in endemic regions, such as Sonora in northern Mexico, where RMSF has caused 1348 non-fatal cases and 247 deaths from 2003 to 2016. A cross-sectional study was conducted with 343 physicians working in medical facilities in Sonora, Mexico. A 25-item questionnaire explored physician knowledge of clinical, epidemiological and preventive aspects of RMSF. Only 62% of physicians agreed that doxycycline should be used as the first choice treatment for children under 8 years with suspected RMSF. Additionally, 40% of primary care physicians correctly identified the time to initiate doxycycline, and 32% correctly identified the case-fatality rate of untreated RMSF in all patients. Inadequate medical knowledge may adversely affect how patients infected with Rickettsia rickettsii are diagnosed and treated. Educational programs that improve the risk perception and medical knowledge about RMSF should be targeted at physicians most likely to have initial contact with diseased patients.

  11. Adolescents get the picture in Mexico.

    Science.gov (United States)

    1999-11-01

    The Mexican Family Planning Association (MEXFAM) started the Gente Joven program in 1986, targeting young people in the neediest urban and rural areas of Mexico to counteract the lack of sexual and reproductive health information and services for the youth. This lack of information has led to over half a million children being born to teenage mothers each year in Mexico. Studies also show that only 1 in 6 sexually active teenager uses some kind of protection against unwanted pregnancies and sexually transmitted diseases. To address this problem, the Gente Joven program disseminates adolescent sexual health information, produces IEC materials, provides adolescent health services and trains health and education professionals in human sexuality. As part of the program, audiovisual equipment was purchased and used since it has shown to be very effective in disseminating information. The purchase of audiovisual equipment for 36 MEXFAM clinics and centers would mean that field level staff would be able to carry out their duties more effectively.

  12. Real-World Economic Outcomes During Time on Treatment Among Patients Who Initiated Sunitinib or Pazopanib as First Targeted Therapy for Advanced Renal Cell Carcinoma: A Retrospective Analysis of Medicare Claims Data.

    Science.gov (United States)

    Vogelzang, Nicholas J; Pal, Sumanta K; Ghate, Sameer R; Li, Nanxin; Swallow, Elyse; Peeples, Miranda; Zichlin, Miriam L; Meiselbach, Mark K; Perez, Jose Ricardo; Agarwal, Neeraj

    2018-06-01

    The median age at renal cell carcinoma (RCC) diagnosis is 64 years. However, few studies have assessed the real-world time on treatment (TOT), health resource utilization (HRU), costs, or treatment compliance associated with targeted therapy use among patients in this age group with RCC. To assess the HRU, costs, and compliance during TOT among Medicare patients aged ≥ 65 years with advanced RCC (aRCC) who initiated first targeted therapy with pazopanib or sunitinib. Patients with aRCC were identified in the 100% Medicare + Part D databases administered by the Centers for Medicare & Medicaid Services. Eligible patients initiated first targeted therapy with sunitinib or pazopanib (index drug) on or after their first diagnosis of secondary neoplasm between October 19, 2009, and January 1, 2014, and were aged ≥ 65 years as of 1 year before first targeted therapy initiation (index date). Included patients were stratified into pazopanib and sunitinib cohorts based on first targeted therapy and matched 1:1 on baseline characteristics using propensity scores. TOT was defined as the time from the index date to treatment discontinuation (prescription gap > 90 days) or death. Compliance was defined as the ratio of drug supply days to TOT. Monthly all-cause costs and costs associated with RCC diagnosis (medical and pharmacy in 2015 U.S. dollars) and HRU (inpatient [admissions, readmissions, and days], outpatient, and emergency room visits) were assessed in the 1-year post-index period during TOT. Matched cohorts' TOT was compared using Kaplan-Meier analyses and univariable Cox models, and compliance, HRU, and costs were compared using Wilcoxon signed-rank tests. Of 1,711 included patients, 526 initiated pazopanib and 1,185 initiated sunitinib. Before matching, more patients in the pazopanib cohort were white, diagnosed in 2010-2014 versus 2006-2009, and had lung metastases compared with the sunitinib cohort (all P < 0.05). The pazopanib cohort also had higher mean

  13. Petroleum exploration and development opportunities in Mexico

    International Nuclear Information System (INIS)

    Jensen, R.; Daschle, R.

    2002-01-01

    This paper presents a historical overview of the energy sector in Mexico, an important player in the world energy market, whose trade and market policies support economic development and foreign investment. Trade, commerce and investment between Canada and Mexico has been increasing steadily ever since the North American Free Trade Agreement (NAFTA) came into effect in January 1994. TransAlta Corporation and Westcoast Energy Inc. are two very active investors in the energy sector. Westcoast has invested in increasing natural gas and oil production from the Cantarell field in the Gulf of Mexico through the Campeche Natural Gas Compression Service Project and the Cantarell Nitrogen Plant. TransAlta has invested in two natural gas fired power plants which are both expected to be in service for the second quarter of 2003. These include the 252 MW Campeche facility and the 259 MW Chihuahua facility. Mexico has proven crude oil reserves of 27 billion barrels, proven natural gas reserves of 30 tcf, and in 2000 had a crude oil production of 3.4 mmbl/d, of which half was exported. The energy sector in Mexico may need about $120 billion of investment by 2010, of which half will be used for crude oil exploration and production, transportation and refining and the other half for natural gas exploration and production, transportation and distribution and power generation. Recently, the Mexican government embarked on two initiatives. The first to increase the productivity and profitability of PEMEX, the largest corporation in Mexico and one of the largest in the world, and to allow a form of private investment in the development of non-associated natural gas fields. This paper discussed the significance of the Multiple Service Contracts (MSC) program which involves domestic and international petroleum exploration and development. It also discussed forms of business organizations, taxation and structuring, financial issues, employment and the North American Free Trade Agreement

  14. Protection gaps in Mexico

    Directory of Open Access Journals (Sweden)

    Andrea Villasenor

    2017-10-01

    Full Text Available With Mexico a major destination – and transit – country for people displaced by violence in the Northern Triangle of Central America, the Mexican government needs urgently to improve its asylum systems and procedures if they are to be fit for purpose.

  15. The Art of Mexico.

    Science.gov (United States)

    Saccardi, Marianne

    1997-01-01

    Provides an annotated bibliography of books for grades K and up which explores the folklore, poetry, fiction, and art of Mexico, and focuses on the Mayans and Aztecs and Diego Rivera and Frida Kahlo. Also suggests various research, reading, drama, music, social studies, physical education, and art activities and lists related videos and Internet…

  16. [Food security in Mexico].

    Science.gov (United States)

    Urquía-Fernández, Nuria

    2014-01-01

    An overview of food security and nutrition in Mexico is presented, based on the analysis of the four pillars of food security: availability, access, utilization of food, and stability of the food supply. In addition, the two faces of malnutrition in Mexico were analyzed: obesity and undernourishment. Data were gathered from the food security indicators of the United Nations's Food and Agriculture Organization, from the Mexican Scale of Food Security, and from the National Health and Nutrition Survey. Mexico presents an index of availability of 3 145 kilocalories per person per day, one of the highest indexes in the world, including both food production and imports. In contrast, Mexico is affected by a double burden of malnutrition: whereas children under five present 14% of stunt, 30% of the adult population is obese. Also, more than 18% of the population cannot afford the basic food basket (food poverty). Using perception surveys, people reports important levels of food insecurity, which concentrates in seven states of the Mexican Federation. The production structure underlying these indicators shows a very heterogeneous landscape, which translates in to a low productivity growth across the last years. Food security being a multidimensional concept, to ensure food security for the Mexican population requires a revision and redesign of public productive and social policies, placing a particular focus on strengthening the mechanisms of institutional governance.

  17. Christmas in Mexico.

    Science.gov (United States)

    Kern County Superintendent of Schools, Bakersfield, CA.

    The Christmas season in Mexico starts on December 16 with "las posadas," a series of religious processions in which families or neighbors reenact Joseph's search for shelter for Mary en route to Bethlehem. Those representing pilgrims travel from home to home until they are finally accepted by those representing innkeepers at a home with…

  18. New Mexico Math Pathways Taskforce Report

    Science.gov (United States)

    New Mexico Higher Education Department, 2016

    2016-01-01

    In April 2015 New Mexico faculty, Dana Center staff, and New Mexico Higher Education (NMHED) co-presented the need for better math pathways statewide. Faculty from 6 institutions (New Mexico State University, New Mexico Highlands University, Dine College, Eastern New Mexico University, El Paso Community College, and San Juan College) participated…

  19. Fatal Rocky Mountain Spotted Fever along the United States-Mexico Border, 2013-2016.

    Science.gov (United States)

    Drexler, Naomi A; Yaglom, Hayley; Casal, Mariana; Fierro, Maria; Kriner, Paula; Murphy, Brian; Kjemtrup, Anne; Paddock, Christopher D

    2017-10-01

    Rocky Mountain spotted fever (RMSF) is an emerging public health concern near the US-Mexico border, where it has resulted in thousands of cases and hundreds of deaths in the past decade. We identified 4 patients who had acquired RMSF in northern Mexico and subsequently died at US healthcare facilities. Two patients sought care in Mexico before being admitted to US-based hospitals. All patients initially had several nonspecific signs and symptoms, including fever, headache, nausea, vomiting, or myalgia, but deteriorated rapidly without receipt of a tetracycline-class antimicrobial drug. Each patient experienced respiratory failure late in illness. Although transborder cases are not common, early recognition and prompt initiation of appropriate treatment are vital for averting severe illness and death. Clinicians on both sides of the US-Mexico border should consider a diagnosis of RMSF for patients with rapidly progressing febrile illness and recent exposure in northern Mexico.

  20. Fatal Rocky Mountain Spotted Fever along the United States–Mexico Border, 2013–2016

    Science.gov (United States)

    Yaglom, Hayley; Casal, Mariana; Fierro, Maria; Kriner, Paula; Murphy, Brian; Kjemtrup, Anne; Paddock, Christopher D.

    2017-01-01

    Rocky Mountain spotted fever (RMSF) is an emerging public health concern near the US–Mexico border, where it has resulted in thousands of cases and hundreds of deaths in the past decade. We identified 4 patients who had acquired RMSF in northern Mexico and subsequently died at US healthcare facilities. Two patients sought care in Mexico before being admitted to US-based hospitals. All patients initially had several nonspecific signs and symptoms, including fever, headache, nausea, vomiting, or myalgia, but deteriorated rapidly without receipt of a tetracycline-class antimicrobial drug. Each patient experienced respiratory failure late in illness. Although transborder cases are not common, early recognition and prompt initiation of appropriate treatment are vital for averting severe illness and death. Clinicians on both sides of the US–Mexico border should consider a diagnosis of RMSF for patients with rapidly progressing febrile illness and recent exposure in northern Mexico. PMID:28930006

  1. Integrating climate change in transportation and land use scenario planning : an example from central New Mexico

    Science.gov (United States)

    2015-04-01

    The Central New Mexico Climate Change Scenario Planning Project, an Interagency Transportation, Land Use, and Climate Change Initiative, utilized a scenario planning process to develop a multiagency transportation- and land use-focused development st...

  2. New Mexico geothermal commercialization planning. Semi-annual progress report, January 1, 1979-June 30, 1979

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez, P.; Scudella, G.; Fedor, D.

    1979-06-01

    The market potential for geothermal energy development in New Mexico is estimated. Barriers to market penetration and geothermal development initiatives were identified. Statutes and regulations affecting geothermal development are appended.

  3. Supply Chain Initiatives Database

    Energy Technology Data Exchange (ETDEWEB)

    None

    2012-11-01

    The Supply Chain Initiatives Database (SCID) presents innovative approaches to engaging industrial suppliers in efforts to save energy, increase productivity and improve environmental performance. This comprehensive and freely-accessible database was developed by the Institute for Industrial Productivity (IIP). IIP acknowledges Ecofys for their valuable contributions. The database contains case studies searchable according to the types of activities buyers are undertaking to motivate suppliers, target sector, organization leading the initiative, and program or partnership linkages.

  4. Radon availability in New Mexico

    International Nuclear Information System (INIS)

    McLemore, V.T.

    1995-01-01

    The New Mexico Bureau of Mines and Mineral Resources (NMBMMR) in cooperation with the Radiation Licensing and Registration Section of the New Mexico Environment Department (NMED) and the US Environmental Protection Agency (EPA) have been evaluating geologic and soil conditions that may contribute to elevated levels of indoor radon throughout New Mexico. Various data have been integrated and interpreted in order to determine areas of high radon availability. The purpose of this paper is to summarize some of these data for New Mexico and to discuss geologic controls on the distribution of radon. Areas in New Mexico have been identified from these data as having a high radon availability. It is not the intent of this report to alarm the public, but to provide data on the distribution of radon throughout New Mexico

  5. U.S.-Mexico energy

    International Nuclear Information System (INIS)

    1991-05-01

    This paper reports that while Mexico's petrochemical industry has grown rapidly, it now faces shortages both in investment funds and in supplies of basic petrochemicals due to a financial crisis in the 1980s. Mexico has undertaken a series of policy reforms aimed at encouraging foreign and private investment, but these efforts have generally failed to entice U.S. investment in Mexico. U.S. petrochemical companies have cited unfavorable market conditions, insufficient basic petrochemical capacity in Mexico, concern about the reversibility of Mexican reforms, inadequate Mexican protection of intellectual property rights, and lack of investment protection for U.S. businesses as impediments to investment in Mexico. Cooperation between the two nations in overcoming these obstacles could help U.S. petrochemical companies maintain their positions in a competitive global market, while at the same time provide Mexico with much needed capital investment and technological expertise

  6. ALARA development in Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Lopez, M.A.M. [Instituto Nacional de Investigaciones Nucleares, Col Lomas de Barrilaco (Mexico)

    1995-03-01

    Even though the ALARA philosophy was formally implemented in the early 1980`s, to some extent, ALARA considerations already had been incorporated into the design of most commercial equipment and facilities based on experience and engineering development. In Mexico, the design of medical and industrial facilities were based on international recommendations containing those considerations. With the construction of Laguna Verde Nuclear Power Station, formal ALARA groups were created to review some parts of its design, and to prepare the ALARA Program and related procedures necessary for its commercial operation. This paper begins with a brief historical description of ALARA development in Mexico, and then goes on to discuss our regulatory frame in Radiation Protection, some aspects of the ALARA Program, efforts in controlling and reducing of sources of radiation, and finally, future perspectives in the ALARA field.

  7. Dust storm, northern Mexico

    Science.gov (United States)

    1983-01-01

    This large dust storm along the left side of the photo, covers a large portion of the state of Coahuila, Mexico (27.5N, 102.0E). The look angle of this oblique photo is from the south to the north. In the foreground is the Sierra Madre Oriental in the states Coahuila and Nuevo Leon with the Rio Grande River, Amistad Reservoir and Texas in the background.

  8. Seismology in Mexico

    Science.gov (United States)

    Lomnitz, C.

    1982-01-01

    Mexico is situated at the intersection of four major crustal Plates: the Americas Plate, the Pacific Plate, the Caribbean Plate, and the Cocos Plate. The interaction of these four plates is very complex. The pattern of earthquake risk is, therefore, among the most complicated in the world. The average release of seismic energy each is 55x1021 ergs-more than twice the figure for California. 

  9. Mexico and the CTBT

    International Nuclear Information System (INIS)

    Aguirre G, J.; Martinez L, J.; Ruiz E, L. J.; Aragon M, I. B.

    2013-10-01

    The Comprehensive Nuclear Test-Ban-Treaty (CTBT) is a treaty that prohibits all the nuclear explosions by anybody and in any place, either on the terrestrial surface, in the atmosphere, under the sea or underground. From the adoption of this Treaty by the United Nations, Mexico has had interest for its entrance in vigor, as integral part to assure the international peace. For this reason, our country signed the Treaty since it was open in September 24, 1996 and three years later ratified it, due to Mexico is part of the group of necessary countries for their entrance in vigor. During 13 years, the country has been committed and helped to the installation of monitoring stations, actions that allow the strengthening of the International System of Surveillance. The purpose of this work is to divulge the Treaty,its technologies and benefits; and also to diffuse the works realized by Mexico regarding the radionuclides monitoring station and noble gases both certified ones for the CTBT. Besides the radionuclides technology, Mexico has taken charge of the installation and operation of the seismic stations and hydro-acoustics that have been certified too. The radionuclides station Rn-44 located in Guerrero Negro, BCS has two technologies, an automated sampler of suspended particles in air brand Cinderella/ARAME and a noble gases system Sauna used for the particles detection of radioactive material gamma emitting and Xenon radioisotopes product of nuclear assays. Both technologies are transmitting data in real time to the International Center of Data. These technologies are shown in this work. (Author)

  10. [Obesity in Mexico].

    Science.gov (United States)

    Dávila-Torres, Javier; González-Izquierdo, José Jesús; Barrera-Cruz, Antonio

    2015-01-01

    Excess body weight (overweight and obesity) is currently recognized as one of the most important challenges of public health in the world, given its size, speed of growth and the negative effect it has on the health of the population that suffers. Overweight and obesity significantly increases the risk of chronic no communicable diseases, premature mortality and the social cost of health. An estimated 90 % of cases of type 2 diabetes mellitus attributable to overweight and obesity. Today, Mexico is second global prevalence of obesity in the adult population, which is ten times higher than that of countries like Japan and Korea. With regard to children, Mexico ranks fourth worldwide obesity prevalence, behind Greece, USA and Italy. In our country, over 70 % of the adult population, between 30 and 60 years are overweight. The prevalence of overweight is higher in men than females, while the prevalence of obesity is higher in women than men. Until 2012, 26 million Mexican adults are overweight and 22 million obese, which represents a major challenge for the health sector in terms of promoting healthy lifestyles in the population and development of public policies to reverse this scenario epidemiology. Mexico needs to plan and implement strategies and action cost effective for the prevention and control of obesity of children, adolescents and adults. Global experience shows that proper care of obesity and overweight, required to formulate and coordinate multisectoral strategies and efficient for enhancing protective factors to health, particularly to modify individual behavior, family and community.

  11. Manufacturing Initiative

    Data.gov (United States)

    National Aeronautics and Space Administration — The Advanced Manufacturing Technologies (AMT) Project supports multiple activities within the Administration's National Manufacturing Initiative. A key component of...

  12. Mexico and the 21st Century Power Partnership: Paving the Way to a Greener, Smarter, More Flexible Grid

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2016-05-01

    The 21st Century Power Partnership's program in Mexico (21CPP Mexico) is one initiative of the Clean Energy Ministerial carried out in cooperation with government and local stakeholders, drawing upon an international community of power system expertise.The overall goal of this program is to support Mexico's power system transformation by accelerating the transition to a reliable, financially robust, and low-carbon system.

  13. Mexico: Rasgos de Su Historia. (Mexico: Highlights of Its History).

    Science.gov (United States)

    Orozco, Cecilio

    Intended for both teachers and students, this publication, written in Spanish, briefly traces Mexico's history from its Conquest in 1519 to the overthrow of Porfirio Diaz in 1910. The following are briefly discussed: Mexico's Conquest in 1519; events immediately after the fall of Tenochtitlan; the War for Independence; Texas' separation from…

  14. Financing options in Mexico`s energy industry

    Energy Technology Data Exchange (ETDEWEB)

    McKenna, J.J. [PricewaterhouseCoopers Securities, Houston, TX (United States)

    1999-10-01

    A series of brief notes accompanied this presentation which was divided into seven sections entitled: (1) capital markets update, (2) Mexican financial market update, (3) financing options in the energy industry, (4) the Venezuelan experience at La Apertura, (5) private and strategic equity alternatives, (6) Pricewaterhouse Coopers Securities, and (7) Mexico energy 2005 prediction. The paper focused on how the financial crisis and merger activity in Latin America will impact electricity reform in Mexico. It was noted that under Mexico`s Policy Proposal for Electricity Reform of the Mexican Electricity Industry, the financial community will seek to back companies in power generation, transportation and distribution. The difficulty of financing government businesses undergoing privatization was also discussed with particular emphasis on the challenge of accepting political and regulatory risks. The Latin private equity market and Canadian investment in Mexico was also reviewed. Since NAFTA (North American Free Trade Agreement) went into affect in 1994, Canadian investment in Mexico has more than tripled. Canadian companies have invested more than C$1.7 billion in Mexico since NAFTA. Pricewaterhouse Coopers Securities is a global investment bank which sees large opportunities in the Mexican energy market. They predict that in five years, Mexico will experience a gradual liberalization of the oil and gas sector, and a full liberalization of the gas pipeline and distribution business and the power generation, transmission and distribution business. 3 figs.

  15. Factors associated with pathways toward concurrent sex work and injection drug use among female sex workers who inject drugs in northern Mexico.

    Science.gov (United States)

    Morris, Meghan D; Lemus, Hector; Wagner, Karla D; Martinez, Gustavo; Lozada, Remedios; Gómez, Rangel María Gudelia; Strathdee, Steffanie A

    2013-01-01

    To identify factors associated with time to initiation of (i) sex work prior to injecting drugs initiation; (ii) injection drug use prior to sex work initiation; and (iii) concurrent sex work and injection drug use (i.e. initiated at the same age) among female sex workers who currently inject drugs (FSW-IDU). Parametric survival analysis of baseline data for time to initiation event. Tijuana and Ciudad Juarez situated on the Mexico-US border. A total of 557 FSW-IDUs aged ≥18 years. Interview-administered surveys assessing context of sex work and injection drug use initiation. Nearly half (n = 258) initiated sex work prior to beginning to inject, a third (n = 163) initiated injection first and a quarter (n = 136) initiated both sex work and injection drug use concurrently. Low education and living in Ciudad Juarez accelerated time to sex work initiation. Being from a southern Mexican state and initiating drug use with inhalants delayed the time to first injection drug use. Having an intimate partner encourage entry into sex work and first injecting drugs to deal with depression accelerated time to initiating sex work and injection concurrently. Early physical abuse accelerated time to initiating sex work and injection, and substantially accelerated time to initiation of both behaviors concurrently. Among female sex workers who currently inject drugs in two Mexican-US border cities, nearly half appear to initiate sex work prior to beginning to inject, nearly one-third initiate injection drug use before beginning sex work and one-quarter initiate both behaviors concurrently. Predictors of these three trajectories differ, and this provides possible modifiable targets for prevention. © 2012 The Authors, Addiction © 2012 Society for the Study of Addiction.

  16. Comparison of Alternative Androgen Receptor-axis-targeted Agent (ARATA) and Docetaxel as Second-line Therapy for Patients With Metastatic Castration-resistant Prostate Cancer With Progression After Initial ARATA in Real-world Clinical Practice in Japan.

    Science.gov (United States)

    Miyake, Hideaki; Sugiyama, Takayuki; Aki, Ryota; Matsushita, Yuto; Tamura, Keita; Motoyama, Daisuke; Ito, Toshiki; Otsuka, Atsushi

    2018-06-01

    The objective of the present study was to assess the oncologic outcomes of patients receiving second-line therapy against metastatic castration-resistant prostate cancer (mCRPC). The present study included 222 consecutive mCRPC patients with progression during initial androgen receptor-axis-targeted agent (ARATA) therapy with either abiraterone acetate (AA) or enzalutamide (Enz). Of these 222 patients, 108 subsequently received an alternative ARATA (AA-to-Enz, n = 49; Enz-to-AA, n = 59) and 114 received docetaxel (DTX; AA-to-DTX, n = 54; Enz-to-DTX, n = 60). The prostate-specific antigen (PSA) level in the 114 patients receiving DTX was significantly greater than that in the 108 patients receiving ARATA. However, no significant differences were found in the remaining parameters between the 2 groups. The PSA response rate, PSA progression-free survival (PFS), and overall survival (OS) during second-line therapy in the DTX group (n = 114) were significantly superior to those for the ARATA group (n = 108; PSA response rate, 42.1% vs. 21.3%; median PSA PFS, 7.2 vs. 4.2 months; median OS, 17.5 vs. 14.5 months). Similar trends were confirmed by comparing these outcomes among 4 therapy groups, with significant differences (PSA response rate, Enz-to-AA vs. AA-to-DTX and Enz-to-AA vs. Enz-to-DTX; PSA PFS, AA-to-Enz vs. Enz-to-AA, AA-to-Enz vs. AA-to-DTX, Enz-to-AA vs. AA-to-DTX, and Enz-to-AA vs. Enz-to-DTX; and OS, Enz-to-AA vs. AA-to-DTX and Enz-to-AA vs. Enz-to-DTX). Furthermore, the introduction of DTX was independently associated with improved PSA PFS, but not OS, on multivariate analysis. Favorable oncologic outcomes can be expected with DTX treatment, rather than with alternative ARATA, for mCRPC patients after failure of an initial ARATA. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Police Victimization Among Persons Who Inject Drugs Along the U.S.-Mexico Border.

    Science.gov (United States)

    Pinedo, Miguel; Burgos, Jose Luis; Zuniga, Maria Luisa; Perez, Ramona; Macera, Caroline A; Ojeda, Victoria D

    2015-09-01

    Problematic policing practices are an important driver of HIV infection among persons who inject drugs (PWID) in the U.S.-Mexico border region. This study identifies factors associated with recent (i.e., past 6 months) police victimization (e.g., extortion, physical and sexual violence) in the border city of Tijuana, Mexico. From 2011 to 2013, 733 PWID (62% male) were recruited in Tijuana and completed a structured questionnaire. Eligible participants were age 18 years or older, injected illicit drugs within the past month, and spoke Spanish or English. Multivariable logistic regression analyses identified correlates of recent experiences of police victimization (e.g., bribes, unlawful confiscation, physical and sexual violence). Overall, 56% of PWID reported a recent police victimization experience in Tijuana. In multivariable logistic regression analyses, factors independently associated with recent police victimization included recent injection of methamphetamine (adjusted odds ratio [AOR] = 1.62; 95% CI [1.18, 2.21]) and recently received injection assistance by a "hit doctor" (AOR = 1.56; 95% CI [1.03, 2.36]). Increased years lived in Tijuana (AOR = 0.98 per year; 95% CI [0.97, 0.99]) and initiating drug use at a later age (AOR = 0.96 per year; 95% CI [0.92, 0.99]) were inversely associated with recent police victimization. Physical drugusing markers may increase PWID susceptibility to police targeting and contribute to experiences of victimization. Interventions aimed at reducing police victimization events in the U.S.-Mexico border region should consider PWID's drug-using behaviors. Reducing problematic policing practices may be a crucial public health strategy to reduce HIV risk among PWID in this region.

  18. Development of distributed target

    CERN Document Server

    Yu Hai Jun; Li Qin; Zhou Fu Xin; Shi Jin Shui; Ma Bing; Chen Nan; Jing Xiao Bing

    2002-01-01

    Linear introduction accelerator is expected to generate small diameter X-ray spots with high intensity. The interaction of the electron beam with plasmas generated at the X-ray converter will make the spot on target increase with time and debase the X-ray dose and the imaging resolving power. A distributed target is developed which has about 24 pieces of thin 0.05 mm tantalum films distributed over 1 cm. due to the structure adoption, the distributed target material over a large volume decreases the energy deposition per unit volume and hence reduces the temperature of target surface, then reduces the initial plasma formalizing and its expansion velocity. The comparison and analysis with two kinds of target structures are presented using numerical calculation and experiments, the results show the X-ray dose and normalized angle distribution of the two is basically the same, while the surface of the distributed target is not destroyed like the previous block target

  19. Natural gas in Mexico

    International Nuclear Information System (INIS)

    Ramirez, M.

    1999-01-01

    A series of overhead viewgraphs accompanied this presentation which focused on various aspects of the natural gas industry in Mexico. Some of the viewgraphs depicted statistics from 1998 regarding natural gas throughput from various companies in North America, natural gas reserves around the world, and natural gas reserves in Mexico. Other viewgraphs depicted associated and non-associated natural gas production from 1988 to 1998 in million cubic feet per day. The Burgos Basin and the Cantarell Basin gas production from 1997 to 2004 was also depicted. Other viewgraphs were entitled: (1) gas processing infrastructure for 1999, (2) cryogenic plant at Cd. PEMEX, (3) average annual growth of dry natural gas production for 1997-2004 is estimated at 5.2 per cent, (4) gas flows for December 1998, (5) PGPB- interconnect points, (6) U.S. Mexico gas trade for 1994-1998, (7) PGPB's interconnect projects with U.S., and (8) natural gas storage areas. Technological innovations in the industry include more efficient gas turbines which allow for cogeneration, heat recovery steam generators which reduce pollutant emissions by 21 per cent, cold boxes which increase heat transfer efficiency, and lateral reboilers which reduce energy consumption and total costs. A pie chart depicting natural gas demand by sector shows that natural gas for power generation will increase from 16 per cent in 1997 to 31 per cent in 2004. The opportunities for cogeneration projects were also reviewed. The Comision Federal de Electricidad and independent power producers represent the largest opportunity. The 1997-2001 investment program proposes an 85 per cent sulphur dioxide emission reduction compared to 1997 levels. This presentation also noted that during the 1998-2001 period, total ethane production will grow by 58 tbd. 31 figs

  20. Mexico: Imports or exports?

    International Nuclear Information System (INIS)

    Estrada, J.

    2002-01-01

    This presentation provides an overview of Mexico's energy sector. Proven oil reserves place Mexico in ninth position in the world and fourth largest in natural gas reserves. Energy is one of the most important economic activities of the country, representing 3 per cent of Gross Domestic Product (GDP). Oil exports represent 8.4 per cent of total exports. Approximately 40 per cent of total public investment is earmarked for energy projects. The author discusses energy resources and energy sector limitations. The energy sector plan for the period 2001-2006 is discussed. Its goals are to ensure energy supply, to develop the energy sector, to stimulate participation of Mexican enterprises, to promote renewable energy sources, and to strengthen international energy cooperation. The regulatory framework is being adapted to increase private investment. Some graphs are presented, displaying the primary energy production and primary energy consumption. Energy sector reforms are reviewed, as are electricity and natural gas reforms. The energy sector demand for 2000-2010 and investment requirements are reviewed, as well as fuel consumption for power generation. The author discusses the National Pipeline System (SNG) and the bottlenecks caused by pressure efficiency in the northeast, flow restriction on several pipeline segments, variability of the Petroleos Mexicanos (PEMEX) own use, and pressure drop on central regions. The entire prospect for natural gas in the country is reviewed, along with the Strategic Gas Program (PEG) consisting of 20 projects, including 4 non-associated natural gas, 9 exploration and 7 optimization. A section dealing with multiple service contracts is included in the presentation. The authors conclude by stating that the priority is a national energy policy to address Mexico's energy security requirements, to increase natural gas production while promoting the diversification of imports, and a regulatory framework to be updated in light of current

  1. Unilateral initiatives

    International Nuclear Information System (INIS)

    Anon.

    1988-01-01

    This paper reports on arms control which is generally thought of in terms of formal negotiations with an opponent, with the resulting agreements embodied in a treaty. This is not surprising, since arms control discussions between opponents are both important and politically visible. There are, however, strong reasons for countries to consider and frequently take unilateral initiatives. To do so is entirely consistent with the established major precepts of arms control which state that arms control is designed to reduce the risk of war, the costs of preparing for war, and the death and destruction if war should come. Unilateral initiatives on what weapons are purchased, which ones are eliminated and how forces are deployed can all relate to these objectives. There are two main categories of motives for unilateral initiatives in arms control. In one category, internal national objectives are the dominant, often sole, driving force; the initiative is undertaken for our own good

  2. Ports Initiative

    Science.gov (United States)

    EPA's Ports Initiative works in collaboration with the port industry, communities, and government to improve environmental performance and increase economic prosperity. This effort helps people near ports breath cleaner air and live better lives.

  3. Gulf of Mexico development

    International Nuclear Information System (INIS)

    Krenz, D.

    1998-01-01

    In recent years, the Gulf of Mexico (GOM) has seen significant deepwater growth. An overview of the GOM deepwater leaseholds by Shell and developments by competing companies is presented. Deepwater GOM developments, total production from the shelf and from deepwater wells, new offshore pipeline capacity and ownership, and processing plant capacity are also discussed. Significant deepwater growth in the Gulf is anticipated. Despite significant economic and technological challenges, the area is judged to be the prime exploration and production opportunity in the lower 48 states of the USA. tabs., figs

  4. Trends in traffic fatalities in Mexico: examining progress on the decade of action for road safety 2011-2020.

    Science.gov (United States)

    Cervantes-Trejo, Arturo; Leenen, Iwin; Fabila-Carrasco, John Stewart; Rojas-Vargas, Roy

    2016-11-01

    We explore demographic, temporal and geographic patterns of 256,588 road traffic fatalities from 1998 to 2013 in Mexico, in context of UN´s decade of action for road safety 2010-2020 (DARS). Combined traffic mortality data and population counts were analyzed using mixed-effects logistic regression, distinguishing sex-age groups, vulnerable and protected road users, and municipal size. Rapid growth from 1998 to 2008 in traffic mortality rates has been reversed since 2009. Most deaths averted are among young male protected road users (reduction of 0.95 fatalities per 100,000 per year in males 12-49). In spite of a steady decrease over the full study period, mortality rates remain high in vulnerable road users over 50, with a high mortality rate of 26 per 100,000 males over 75 years in 2013. Progress on the reduction of deaths advances in Mexico, in line with DARS targets. National road safety efforts require strengthening. Initiatives should target vulnerable road users, specifically adults >50 years in urban areas. Strengthening of drink driving programs aimed at young drivers/occupants is promising.

  5. Gulf of Mexico Regional Collaborative Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Judd, Kathleen S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Judd, Chaeli [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Engel-Cox, Jill A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Gulbransen, Thomas [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Anderson, Michael G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Woodruff, Dana L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Thom, Ronald M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Guzy, Michael [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hardin, Danny [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Estes, Maury [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2007-12-01

    This report presents the results of the Gulf of Mexico Regional Collaborative (GoMRC), a year-long project funded by NASA. The GoMRC project was organized around end user outreach activities, a science applications team, and a team for information technology (IT) development. Key outcomes are summarized below for each of these areas. End User Outreach; Successfully engaged federal and state end users in project planning and feedback; With end user input, defined needs and system functional requirements; Conducted demonstration to End User Advisory Committee on July 9, 2007 and presented at Gulf of Mexico Alliance (GOMA) meeting of Habitat Identification committee; Conducted significant engagement of other end user groups, such as the National Estuary Programs (NEP), in the Fall of 2007; Established partnership with SERVIR and Harmful Algal Blooms Observing System (HABSOS) programs and initiated plan to extend HABs monitoring and prediction capabilities to the southern Gulf; Established a science and technology working group with Mexican institutions centered in the State of Veracruz. Key team members include the Federal Commission for the Protection Against Sanitary Risks (COFEPRIS), the Ecological Institute (INECOL) a unit of the National Council for science and technology (CONACYT), the Veracruz Aquarium (NOAA’s first international Coastal Ecology Learning Center) and the State of Veracruz. The Mexican Navy (critical to coastal studies in the Southern Gulf) and other national and regional entities have also been engaged; and Training on use of SERVIR portal planned for Fall 2007 in Veracruz, Mexico Science Applications; Worked with regional scientists to produce conceptual models of submerged aquatic vegetation (SAV) ecosystems; Built a logical framework and tool for ontological modeling of SAV and HABs; Created online guidance for SAV restoration planning; Created model runs which link potential future land use trends, runoff and SAV viability; Analyzed SAV

  6. The Merida Initiative: Security-Surveillance Harmonization in Latin America

    OpenAIRE

    Nelson Arteaga Botello

    2009-01-01

    This work analyses the Merida Initiative, whose objective is to coordinate the information systems used against terrorism, organized crime, and drug and arms trafficking between the United States, Mexico and Central America. This implies the introduction of communication equipment, data bases and surveillance technology, which not only reinforces the security policies of the ‘western hemisphere’, but also consolidates and broadens the spaces of exception in Mexico and Central America, thus er...

  7. 21 CFR 808.81 - New Mexico.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false New Mexico. 808.81 Section 808.81 Food and Drugs... and Local Exemptions § 808.81 New Mexico. The following New Mexico medical device requirement is... from preemption under section 521(b) of the act: New Mexico Statutes Annotated, section 67-36-16(F...

  8. Binational collaboration to study Gulf of Mexico's harmful algae

    Science.gov (United States)

    Soto, Inia; Hu, Chuanmin; Steidinger, Karen; Muller-Karger, Frank; Cannizzaro, Jennifer; Wolny, Jennifer; Cerdeira-Estrada, Sergio; Santamaria-del-Angel, Eduardo; Tafoya-del-Angel, Fausto; Alvarez-Torres, Porfirio; Herrera Silveira, Jorge; Allen, Jeanne

    2012-01-01

    Blooms of the toxic marine dinoflagellate Karenia brevis cause massive fish kills and other public health and economic problems in coastal waters throughout the Gulf of Mexico [Steidinger, 2009]. These harmful algal blooms (HABs) are a gulf-wide problem that require a synoptic observing system for better serving decision-making needs. The major nutrient sources that initiate and maintain these HABs and the possible connectivity of blooms in different locations are important questions being addressed through new collaborations between Mexican and U.S. researchers and government institutions. These efforts were originally organized under the U.S./Mexico binational partnership for the HABs Observing System (HABSOS), led by the U.S. Environmental Protection Agency's Gulf of Mexico Program (EPAGMP) and several agencies in Veracruz, Mexico, since 2006. In 2010 these efforts were expanded to include other Mexican states and institutions with the integrated assessment and management of the Gulf of Mexico Large Marine Ecosystem (GoMLME) program sponsored by the Global Environment Facility (GEF), the United Nations Industrial Development Organization (UNIDO), the Secretaría de Medio Ambiente y Recursos Naturales (SEMARNAT), and the National Oceanic and Atmospheric Administration (NOAA).

  9. CERN: Fixed target targets

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1993-03-15

    Full text: While the immediate priority of CERN's research programme is to exploit to the full the world's largest accelerator, the LEP electron-positron collider and its concomitant LEP200 energy upgrade (January, page 1), CERN is also mindful of its long tradition of diversified research. Away from LEP and preparations for the LHC proton-proton collider to be built above LEP in the same 27-kilometre tunnel, CERN is also preparing for a new generation of heavy ion experiments using a new source, providing heavier ions (April 1992, page 8), with first physics expected next year. CERN's smallest accelerator, the LEAR Low Energy Antiproton Ring continues to cover a wide range of research topics, and saw a record number of hours of operation in 1992. The new ISOLDE on-line isotope separator was inaugurated last year (July, page 5) and physics is already underway. The remaining effort concentrates around fixed target experiments at the SPS synchrotron, which formed the main thrust of CERN's research during the late 1970s. With the SPS and LEAR now approaching middle age, their research future was extensively studied last year. Broadly, a vigorous SPS programme looks assured until at least the end of 1995. Decisions for the longer term future of the West Experimental Area of the SPS will have to take into account the heavy demand for test beams from work towards experiments at big colliders, both at CERN and elsewhere. The North Experimental Area is the scene of larger experiments with longer lead times. Several more years of LEAR exploitation are already in the pipeline, but for the longer term, the ambitious Superlear project for a superconducting ring (January 1992, page 7) did not catch on. Neutrino physics has a long tradition at CERN, and this continues with the preparations for two major projects, the Chorus and Nomad experiments (November 1991, page 7), to start next year in the West Area. Delicate neutrino oscillation effects could become visible for the first

  10. Mexico Wind Resource Assessment Project

    Energy Technology Data Exchange (ETDEWEB)

    Schwartz, M.N.; Elliott, D.L.

    1995-05-01

    A preliminary wind energy resource assessment of Mexico that produced wind resource maps for both utility-scale and rural applications was undertaken as part of the Mexico-U.S. Renewable Energy Cooperation Program. This activity has provided valuable information needed to facilitate the commercialization of small wind turbines and windfarms in Mexico and to lay the groundwork for subsequent wind resource activities. A surface meteorological data set of hourly data in digital form was utilized to prepare a more detailed and accurate wind resource assessment of Mexico than otherwise would have been possible. Software was developed to perform the first ever detailed analysis of the wind characteristics data for over 150 stations in Mexico. The hourly data set was augmented with information from weather balloons (upper-air data), ship wind data from coastal areas, and summarized wind data from sources in Mexico. The various data were carefully evaluated for their usefulness in preparing the wind resource assessment. The preliminary assessment has identified many areas of good-to-excellent wind resource potential and shows that the wind resource in Mexico is considerably greater than shown in previous surveys.

  11. CERN: Fixed target targets

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    Full text: While the immediate priority of CERN's research programme is to exploit to the full the world's largest accelerator, the LEP electron-positron collider and its concomitant LEP200 energy upgrade (January, page 1), CERN is also mindful of its long tradition of diversified research. Away from LEP and preparations for the LHC proton-proton collider to be built above LEP in the same 27-kilometre tunnel, CERN is also preparing for a new generation of heavy ion experiments using a new source, providing heavier ions (April 1992, page 8), with first physics expected next year. CERN's smallest accelerator, the LEAR Low Energy Antiproton Ring continues to cover a wide range of research topics, and saw a record number of hours of operation in 1992. The new ISOLDE on-line isotope separator was inaugurated last year (July, page 5) and physics is already underway. The remaining effort concentrates around fixed target experiments at the SPS synchrotron, which formed the main thrust of CERN's research during the late 1970s. With the SPS and LEAR now approaching middle age, their research future was extensively studied last year. Broadly, a vigorous SPS programme looks assured until at least the end of 1995. Decisions for the longer term future of the West Experimental Area of the SPS will have to take into account the heavy demand for test beams from work towards experiments at big colliders, both at CERN and elsewhere. The North Experimental Area is the scene of larger experiments with longer lead times. Several more years of LEAR exploitation are already in the pipeline, but for the longer term, the ambitious Superlear project for a superconducting ring (January 1992, page 7) did not catch on. Neutrino physics has a long tradition at CERN, and this continues with the preparations for two major projects, the Chorus and Nomad experiments (November 1991, page 7), to start next year in the West Area. Delicate neutrino oscillation effects could become

  12. Texas-Mexico multimodal transportation: developments in Mexico

    Science.gov (United States)

    Boske, Leigh B.

    1994-03-01

    This presentation highlights the results of a recently completed study that examines the Texas- Mexico multimodal transport system already in place, current plans for improvements or expansion, and opportunities and constraints faced by each transport mode -- motor carriage, rail, maritime, and air. Particular emphasis is given to findings regarding transportation developments in Mexico. The study concludes that in Mexico, all modes are working at establishing new services and strategic alliances, intermodal arrangements are on the rise, and private-sector participation in infrastructure improvements is growing daily at Mexican seaports and airports as well as within that nation's highway and rail systems. This presentation looks at developments that concern privatization, deregulation, infrastructure improvements, financing arrangements, and new services in Mexico.

  13. Initial Study

    DEFF Research Database (Denmark)

    Torp, Kristian

    2009-01-01

    increased. In the initial study presented here, the time it takes to pass an intersection is studied in details. Two major signal-controlled four-way intersections in the center of the city Aalborg are studied in details to estimate the congestion levels in these intersections, based on the time it takes...

  14. The first educational interferometer in Mexico (FEYMANS): A novel project

    Science.gov (United States)

    Villicana Pedraza, Ilhuiyolitzin; Guesten, Rolf; Saucedo Morales, Julio Cesar; Carreto, Francisco; Valdes Estrada, Erik; Wendolyn Blanco Cardenas, Monica; Rodríguez Garza, Carolina B.; Pech Castillo, Gerardo A.; Ángel Vaquerizo, Juan

    2016-07-01

    An interferometer is composed of several radio telescopes (dishes) separated by a defined distance and used in synchrony. This kind of array produces a superior angular resolution, better than the resolution achieved by a single dish of the same combined area. In this work we propose the First Educational Youth Mexican Array North South, FEYMANS. It consists of an educational interferometer with initially four dishes. This array harvests Mexico's geography by locating each dish at the periphery of the country; creating new scientific links of provincial populations with the capital. The FEYMANS project focus in high school students and their projects on physics, chemistry and astronomy as a final project. Also, it can be used for bachelor theses. The initial and central dish-node is planed to be in Mexico City. After its construction, the efforts will focus to build subsequent nodes, on the Northwest region, Northeast, or Southeast. Region Northwest will give service to Baja California, Sonora and Chihuahua states. Region Northeast will cover Coahuila, Nuevo Leon and Tamaulipas. Finally, region Southeast will give access to Yucatan, Quintana Roo, Campeche, Tabasco and Chiapas. This project has been conceived by young professional astronomers and Mexican experts that will operate each node. Also, we have the technical support of the "Max Planck Institute fuer Radioastronomy in Bonn Germany" and the educational model of the "PARTNeR" project in Spain. This interferometer will be financed by Mexico's Federal Congress and by Mexico City's Legislative Assembly (ALDF).

  15. Mexico City aerosol study

    International Nuclear Information System (INIS)

    Falcon, Y.I.; Ramirez, C.R.

    1987-01-01

    A major task in the field of air pollution monitoring is the development of devices for determining the mass and composition of airborne particulate matter as a function of size - and time. The sample collection device must be designed giving consideration to the nature of the aerosol and to the effects of the aerosol on human health. It has been established that particles smaller than 3.5 μm in diameter can penetrate deeply into the human respiratory system, and that larger particles are trapped in the upper respiratory passages. For these reasons, it is desirable to use a dichotomous sampler to collect particles in two size ranges, rather than to collect total particulates on a single filter. The authors discuss a study in Mexico City using a dichotomous sampler

  16. Mexico introduces pentavalent vaccine.

    Science.gov (United States)

    1999-08-01

    Combination vaccines have been introduced in Mexico. The national immunization program has incorporated the measles-mumps-rubella (MMR) vaccines in 1998, and the pentavalent vaccine in 1999. The two categories of antigen composition in combination vaccines are: 1) multiple different antigenic types of a single pathogen, such as the 23 valent pneumococcal polysaccharide vaccine, and 2) antigens from different pathogens causing different diseases, such as the DPT and MMR vaccines. Pentavalent vaccines are included in the second category. The vaccine protects against diphtheria, tetanus, pertussis, hepatitis B, and other diseases produced by Haemophilus influenzae type b (Hib). Combined diphtheria, tetanus, pertussis, hepatitis B, and Haemophilus influenza type b (DTP-HB/Hib) vaccine has been distributed to 87% of Mexican children under 1 year of age. Over 800,000 doses of pentavalent vaccine have been administered.

  17. New Mexico, 2010 Census Place

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  18. New Mexico, 2010 Congressional Districts

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  19. New Mexico Urban Areas - Current

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The TIGER/Line Shapefiles are an extract of selected geographic and cartographic information from the Census MAF/TIGER database. The Census MAF/TIGER database...

  20. August 1973 Veracruz, Mexico Images

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — South of Veracruz, southeastern Mexico. Damage: Severe. The earthquake caused heavy damage in the states of Morelos, Puebla, and Veracruz. Thousands were left...

  1. United States Strategy for Mexico

    National Research Council Canada - National Science Library

    Centner, Robert C

    2005-01-01

    The security and stability of Mexico is of national interest to the United States, and a strong, effective alliance between the two countries is pivotal to our national defense strategy and economic prosperity...

  2. Target laboratory

    International Nuclear Information System (INIS)

    Ephraim, D.C.; Pednekar, A.R.

    1993-01-01

    A target laboratory to make stripper foils for the accelerator and various targets for use in the experiments is set up in the pelletron accelerator facility. The facilities available in the laboratory are: (1) D.C. glow discharge setup, (2) carbon arc set up, and (3) vacuum evaporation set up (resistance heating), electron beam source, rolling mill - all for target preparation. They are described. Centrifugal deposition technique is used for target preparation. (author). 3 figs

  3. [Public and private: insurance companies and medical care in Mexico].

    Science.gov (United States)

    Tamez, S; Bodek, C; Eibenschutz, C

    1995-01-01

    During the late 70's and early 80's in Mexico, as in the rest of Latin-America, sanitary policies were directed to support the growth of the private sector of health care at the expense of the public sector. This work analyzes the evolution of the health insurance market as a part of the privatization process of health care. The analysis based on economic data, provides the political profile behind the privatization process as well as the changes in the relations between the State and the health sector. The central hypothesis is that the State promotes and supports the growth of the private market of medical care via a series of legal, fiscal and market procedures. It also discusses the State roll in the legal changes related to the national insurance activity. A comparative analysis is made about the evolution of the insurance industry in Argentina, Brazil, Chile and Mexico during the period 1986-1992, with a particular enfasis in the last country. One of the principal results is that the Premium/GNP and Premium/per capita, display a general growth in the 4 countries. This growth is faster for Mexico for each one) because the privatization process occurred only during the most recent years. For the 1984-1991 period in Mexico the direct premium as percentage of the GNP raised from 0.86% to 1.32%. If one focussed only in the insurance for health and accidents branches the rice goes form 8.84% in 1984 to 19.08% in 1991. This indicates that the insurance industry is one of the main targets of the privatization process of the health care system in Mexico. This is also shown by the State support to fast expansion of the big medical industrial complex of the country. Considering this situation in the continuity of the neoliberal model of Mexico, this will profound the inequity and inequality.

  4. Ice targets

    International Nuclear Information System (INIS)

    Pacheco, C.; Stark, C.; Tanaka, N.; Hodgkins, D.; Barnhart, J.; Kosty, J.

    1979-12-01

    This report presents a description of ice targets that were constructed for research work at the High Resolution Spectrometer (HRS) and at the Energetic Pion Channel and Spectrometer (EPICS). Reasons for using these ice targets and the instructions for their construction are given. Results of research using ice targets will be published at a later date

  5. Transportation energy use in Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Sheinbaum, C.; Meyers, S.; Sathaye, J.

    1994-07-01

    This report presents data on passenger travel and freight transport and analysis of the consequent energy use in Mexico during the 1970--1971 period. We describe changes in modal shares for passenger travel and freight transport, and analyze trends in the energy intensity of different modes. We look in more detail at transportation patterns, energy use, and the related environmental problems in the Mexico City Metropolitan Area, and also discuss policies that have been implemented there to reduce emissions from vehicles.

  6. Uranium resources in New Mexico

    International Nuclear Information System (INIS)

    McLemore, V.T.; Chenoweth, W.L.

    1989-01-01

    For nearly three decades (1951-1980), the Grants uranium district in northwestern New Mexico produced more uranium than any other district in the world. The most important host rocks containing economic uranium deposits in New Mexico are sandstones within the Jurassic Morrison Formation. Approximately 334,506,000 lb of U 3 O 8 were produced from this unit from 1948 through 1987, accounting for 38% of the total uranium production from the US. All of the economic reserves and most of the resources in New Mexico occur in the Morrison Formation. Uranium deposits also occur in sandstones of Paleozoic, Triassic, Cretaceous, Tertiary, and Quaternary formations; however, only 468,680 lb of U 3 O 8 or 0.14% of the total production from New Mexico have been produced from these deposits. Some of these deposits may have a high resource potential. In contrast, almost 6.7 million lb of U 3 O 8 have been produced from uranium deposits in the Todilto Limestone of the Wanakah Formation (Jurassic), but potential for finding additional economic uranium deposits in the near future is low. Other uranium deposits in New Mexico include those in other sedimentary rocks, vein-type uranium deposits, and disseminated magmatic, pegmatitic, and contact metasomatic uranium deposits in igneous and metamorphic rocks. Production from these deposits have been insignificant (less than 0.08% of the total production from New Mexico), but there could be potential for medium to high-grade, medium-sized uranium deposits in some areas. Total uranium production from New Mexico from 1948 to 1987 amounts to approximately 341,808,000 lb of U 3 O 8 . New Mexico has significant uranium reserves and resources. Future development of these deposits will depend upon an increase in price for uranium and lowering of production costs, perhaps by in-situ leaching techniques

  7. Manufacture of reconstruction-bricks in Mexico

    Science.gov (United States)

    Rojas-Valencia, Ma. Neftalí; Penagos, Armando Aguilar; Rojas, Denise Y. Fernández; López, Alberto López; Gálves, David Morillón

    2017-12-01

    In Mexico, around 33.600 tons of construction wastes are generated every day, Mexico City contributing for around tons/day, with fewer than 1.000 tons/day being sent to be recycled. For that reason the purpose of this study was to manufacture sustainable bricks, based on three types of wastes generated in the building industry: wood cutting residues, wastes from the excavation process (From Coapa and Cuautlancingo, Puebla, Mexico) and recycled aggregates. Water was added as kneading material, and Opuntia ficus-indica (mucilage) was supplemented as natural additive to improve the workability of the mixtures. Conventional firing process was substituted by drying in a solar drying chamber. Nine mixtures were prepared using 62% excavation wastes, 4% wood cutting residues and 11%, 17% and 34% recycled aggregates. These mixtures were classified in two groups depending on their granulometry: the first one denominated cementitious recycled aggregates only having granulometry from 25.4 mm, 9.52 mm to 6.35 mm to fines and the second group denominated all in one recycled aggregates having granulometry of 6.35 mm to fines. The quality of the sustainable bricks was evaluated according to compressive strength and water absorption parameters. The results of nine mixtures showed that the reconstruction-bricks manufactured with the mixture seven consisting of 9.52 mm and 6.35 mm construction residues (all in one) fines presented the highest strength values, lowest maximum initial absorption (4 g/min) compared to the norm NMX-C-037-ONNCCE-2013 which establishes that the maximum limit for walls exposed to the outside is 5 g/min. Using a solar desiccator made from construction residues, the bricks were dried in 11 days, the maximum temperature was 76 °C and the maximum solar radiation captured was 733.4 W/m2.

  8. Defective modernization and health in Mexico.

    Science.gov (United States)

    Simonelli, J M

    1987-01-01

    This paper uses data gathered in a semi-arid, mountain region of the border state of Sonora, Mexico to illustrate that modernization and the importation of urban ideas and values can influence health status in unexpected ways. It traces the historic process of modernization in a rural municipio, relating this to social promises and economic cycles in Mexico. Modernization is seen to encompass life standard improvements and access to medical care; extension of road and transportation systems; and the widespread availability of information and education, as well as lifestyle changes required to incorporate these 'urban' influences. Reviewing the link between climate and health in arid lands, the paper notes that such modernization can be a well-meaning intrusion upon a set of cultural and social practices which had proved adaptive in dealing with climatic extremes. Initial modernization produces impressive declines in mortality and morbidity, as illustrated in an analysis of mortality figures and causes in relation to age cohorts and decades for the years 1955-1984. However, reductions in epidermic-related infant mortality are shown to be offset by increases in deaths due to trauma, chronic conditions and endemic disease. An analysis of morbidity for the year 1983-84 indicates that continuing high rates of infectious disease are related to conditions which result from increasingly defective modernization. To maintain technology, including water, electrical, and sewage systems, continual capital expenditure on both the public and private level is required. The economic crisis in Mexico is reducing available funds at a time when the community has adjusted its traditional lifestyle to incorporate technological improvements. In light of this, it is likely that inroads against infectious disease will not just continue to be stalemated, but could actually be reversed. This finding has implications for towns and villages on both sides of the Mexican-American border.

  9. Natural Analog Studies at Pena Blanca, Mexico

    Energy Technology Data Exchange (ETDEWEB)

    A.M. Simmons

    2005-07-11

    The significance of the Pena Blanca uranium deposits in the State of Chihuahua, Mexico as potential natural analogs for a nuclear waste repository in unsaturated welded tuff was first recognized in the 1980s. In the 1970s, the Pena Blanca region was a major target of uranium exploration and exploitation by the Mexican government. Since then the Nopal I uranium deposit has been studied extensively by researchers in the U.S., Mexico, and Europe. The Nopal I deposit represents an environment similar to that of the proposed high-level radioactive waste repository at Yucca Mountain in many ways. Both are located in semi-arid regions. Both are located in Tertiary rhyolitic tuffs overlying carbonate rocks that have been subjected to basin and range-style tectonic deformation. Both are located in a chemically oxidizing, unsaturated zone 200 m or more above the water table. The alteration of uraninite to secondary minerals at Nopal I may be similar to the alteration of uranium fuel rods in this type of setting. Investigations at Nopal I and in the surrounding Sierra Pena Blanca have included detailed outcrop mapping, hydrologic and isotopic studies of flow and transport, studies of mineral alteration, modeling, and performance assessment.

  10. Natural Analog Studies at Pena Blanca, Mexico

    International Nuclear Information System (INIS)

    A.M. Simmons

    2005-01-01

    The significance of the Pena Blanca uranium deposits in the State of Chihuahua, Mexico as potential natural analogs for a nuclear waste repository in unsaturated welded tuff was first recognized in the 1980s. In the 1970s, the Pena Blanca region was a major target of uranium exploration and exploitation by the Mexican government. Since then the Nopal I uranium deposit has been studied extensively by researchers in the U.S., Mexico, and Europe. The Nopal I deposit represents an environment similar to that of the proposed high-level radioactive waste repository at Yucca Mountain in many ways. Both are located in semi-arid regions. Both are located in Tertiary rhyolitic tuffs overlying carbonate rocks that have been subjected to basin and range-style tectonic deformation. Both are located in a chemically oxidizing, unsaturated zone 200 m or more above the water table. The alteration of uraninite to secondary minerals at Nopal I may be similar to the alteration of uranium fuel rods in this type of setting. Investigations at Nopal I and in the surrounding Sierra Pena Blanca have included detailed outcrop mapping, hydrologic and isotopic studies of flow and transport, studies of mineral alteration, modeling, and performance assessment

  11. Considerations to the nuclear safety in Mexico

    International Nuclear Information System (INIS)

    Salas M, B.

    2006-01-01

    The uncertain future of the hydrocarbons like main source of energy, force us to think on the nuclear energy as the suitable substitute that we can inherit to those future generations. Mexico therefore should multiply the number of nuclear power centrals and to be in this way prepared for the new challenges, however, it is necessary and advisable, to restate the mexican nuclear plan that includes mainly the transparency. The 'WANO Report' (World Association of Nuclear Operators - for their initials in English), result of a technical audit to the Nuclear Power station of Laguna Verde (CNLV), it is a polemic topic, because in accordance with David Lochbaum of 'The Union of Concerned Scientists' of the United States of America and of John Large of 'Large and Associates' of the Great Britain, the security in the CNLV is questionable. The pronouncements of concern of Abel J. Gonzalez and Ken E. Brockman, high officials of the International Atomic Energy Agency who took knowledge of diverse irregularities in the CNLV, should be analysis reason for to take actions in pro of the future of the nuclear energy in Mexico. (Author)

  12. Governability in Contemporary Mexico

    Directory of Open Access Journals (Sweden)

    Leonardo Curzio Gutiérrez

    1998-04-01

    Full Text Available Given the difficulties to establish a concept of governability and the frequent ideological usage of the term, it is much more operative to turn to the principle of governability, in the broad sense, which supports itself on five pillars: the political legitimacy of the government, the governmental efficiency to attend to the demands of society, the existence of shared social project, the agreement with the principle special interest groups, and international viability. The analysis of the structure and relevance of these five points during the long period of political transition that Mexico underwent between 1988 and 1997 shows how it was possible for this country to play off certain factors against each other in order to secure governability and safeguard against the consequences of any resultant imbalances. Between 1998-1993, the government of Salinas de Gotari based itself on the viability of a neoliberal project within an international context, and on this projectís attention to domestic demands as well as on the governmentís pact with elites. Institutional integration and legitimacy made up, then, for a process of discreet liberalization and the lack of democratic electoral commitment, which culminated in the PRI’s 1994 elections victory.The assassination of Colosia, though, and the appearance of the EZLN and the subsequent crisis surrounding the peso’s devaluation that accompanied Ernesto Zedilloís rise to power soon led to the collapse of those pillars of support. Crowning the process of the silenttransition were the elections of 1997, which makes it possible to say that in Mexico today there are now smooth elections, but that reform of the State is still unresolved —a subject that includes the reduction of the president’s competence. Seen in the short term, the most direct threats to Mexico’s governability will come as a result of the lack of attention to those demands of society’s underprivileged and the ill

  13. Biodiversity in the Madrean Archipelago of Sonora, Mexico

    Science.gov (United States)

    Thomas R. Van Devender; Sergio Avila-Villegas; Melanie Emerson; Dale Turner; Aaron D. Flesch; Nicholas S. Deyo

    2013-01-01

    Flowery rhetoric often gives birth to new terms that convey images and concepts, lead to inspiration and initiative. On the 1892-1894 expedition to resurvey the United States-Mexico boundary, Lieutenant David Dubose Gaillard described the Arizona-Sonora borderlands as “bare, jagged mountains rising out of the plains like islands from the sea” (Mearns 1907; Hunt and...

  14. 75 FR 28555 - Executive Green ICT & Energy Efficiency Trade Mission to Mexico City, Mexico

    Science.gov (United States)

    2010-05-21

    ... Trade Mission to Mexico City, Mexico AGENCY: International Trade Administration, Department of Commerce... Trade Mission to Mexico City from September 27-29, 2010. This Executive led mission will focus on... & Energy Efficiency conference will take place at the World Trade Center in Mexico City. Relevant issues on...

  15. Mexico's critical choices

    International Nuclear Information System (INIS)

    Marcos, E.

    1990-01-01

    In Mexico, the 1982 fall in international oil prices shook the national conscience and pushed the Mexican people in search of a new national image and toward the choices they must make to attain that image. But, according to the author of this paper, the country as a whole has already made critical choices for overall strategy and there are reasons for optimism. In the current economic environment of growing domestic demand and enhanced international competitiveness, the author sees PEMEX (the Mexican national oil company) facing not only the challenge of responding to the rapid changes taking place in the Mexican economy, but also making a significant contribution toward the solid and stable growth of the country. The relevant question is how PEMEX will live up to these expectations. This paper describes several steps PEMEX has taken already or is preparing to take in order to meet this challenge, including: investment in the domestic petrochemical industry; entry into the Eurobond market; development of new methods of project financing

  16. New Mexico HUC-10 Boundaries - 2013

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data set is a complete digital hydrologic unit boundary layer to the watershed (10-digit) 10th level for the State of New Mexico. This data set consists of...

  17. Mexico Terrain Corrected Free Air Anomalies (97)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This 2' gravity anomaly grid for Mexico, North-Central America and the Western Caribbean Sea is NOT the input data set used in the development of the MEXICO97 model....

  18. New Mexico HUC-8 Boundaries - 2013

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data set is a complete digital hydrologic unit boundary layer to the Subbasin (8-digit) 8th level for the State of New Mexico. This data set consists of...

  19. HSIP Fire Stations in New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Fire Stations in New Mexico Any location where fire fighters are stationed or based out of, or where equipment that such personnel use in carrying out their jobs is...

  20. Rationale, Design, and Baseline Data of the Insulin Glargine (Lantus) Versus Insulin Detemir (Levemir) Treat-To-Target (L2T3) Study: A Multinational, Randomized Noninferiority Trial of Basal Insulin Initiation in Type 2 Diabetes

    NARCIS (Netherlands)

    Swinnen, Sanne G. H. A.; Snoek, Frank J.; Dain, Marie-Paule; DeVries, J. Hans; Hoekstra, Joost B. L.; Holleman, Frits

    2009-01-01

    Objective: To discuss the design and baseline data of the Lantus (R) (sanofi-aventis, Paris, France) versus Levemir (R) (Novo Nordisk A/S, Bagsvaerd, Denmark) Treat-To-Target (L2T3) study, a multinational, randomized comparison between the basal insulin analogs insulin glargine and insulin detemir.

  1. Monetary Targeting

    Directory of Open Access Journals (Sweden)

    Krušković Borivoje D.

    2015-09-01

    Full Text Available In this paper we test the existence of long-term relationship between money supply and inflation, money supply and GDP and money supply and unemployment. Three independent panel cointegration regressions are evaluated where money supply is the explanatory variable, while inflation, GDP and unemployment rates occur as dependent variables. The sample consists of 17 countries (Australia, Canada, Chile, Denmark, Israel, Japan, South Korea, Mexico, New Zealand, Poland, Switzerland, United Kingdom and United States. The data are annual and refer to the period from 1990 to 2013. The results of the empirical analysis in this paper show that there is no significant long-term relationship between inflation and money supply, while there is statistically significant long-term relationship between GDP and money supply, as well as between unemployment rates and the money supply.

  2. Measurements of VOCs in Mexico City during the MILAGRO Campaign

    Science.gov (United States)

    Baker, A. K.; Beyersdorf, A. J.; Blake, N. J.; Meinardi, S.; Atlas, E.; Rowland, F.; Blake, D. R.

    2006-12-01

    During March of 2006 we participated in MILAGRO (Megacities Initiative: Local and Global Research Observations), a multi-platform campaign to measure pollutants in and in outflow from the Mexico City metropolitan area. As part of MILAGRO we collected whole air canister samples at two Mexico City ground sites: the Instituto Mexicano del Petroleo, located in the city, northeast of the center, and the Universidad Technologica de Tecamac, a suburban site approximately 50 km northeast of the city center. Samples were also collected in various other locations throughout Mexico City. Over 300 whole air samples were collected and analyzed for a wide range of volatile organic compounds (VOCs) including methane, carbon monoxide, nonmethane hydrocarbons (NMHCs) and halocarbons. Propane was the most abundant NMHC at both the urban and suburban locations, with mixing ratios frequently in excess of 10 parts per billion at both locations. This is likely the result of the widespread use of liquefied petroleum gas (LPG) of which propane is the major component. For most species, median mixing ratios at the urban sites were significantly greater than at the suburban site. Here we compare results from both urban and suburban locations and also examine the influence of transport on the composition of outflow from Mexico City.

  3. Initiatives: Swaziland.

    Science.gov (United States)

    Mdluli, N

    1996-04-01

    Men in Swaziland have many misconceptions and fears about the use of modern contraception. The Family Life Association of Swaziland (FLAS) operates in that context to increase men's level of awareness of the importance of family planning, while assuring them that contraceptive use is safe. FLAS has undertaken a number of interventions to help increase male involvement in family planning, to increase family planning knowledge, to address men's fears and negative attitudes toward the family planning concept and certain contraceptive methods, and to assure them that family planning is a universal practice. Approximately 2000 men were reached annually through education interventions in army barracks on family planning, sexually transmitted diseases (STDs), and AIDS; a comprehensive educational program was established in Usuthu Pulp, Big Bend, Mhlume, Shiselweni Forest, and Cadbury industries; roadshows reached out to a number of target audiences; and a male symposium of 60 men from the Manzini region was held to discuss the importance of family planning, STDs, and AIDS in the country.

  4. The University of New Mexico Center for Molecular Discovery

    Science.gov (United States)

    Edwards, Bruce S.; Gouveia, Kristine; Oprea, Tudor I.; Sklar, Larry A.

    2015-01-01

    The University of New Mexico Center for Molecular Discovery (UNMCMD) is an academic research center that specializes in discovery using high throughput flow cytometry (HTFC) integrated with virtual screening, as well as knowledge mining and drug informatics. With a primary focus on identifying small molecules that can be used as chemical probes and as leads for drug discovery, it is a central core resource for research and translational activities at UNM that supports implementation and management of funded screening projects as well as “up-front” services such as consulting for project design and implementation, assistance in assay development and generation of preliminary data for pilot projects in support of competitive grant applications. The HTFC platform in current use represents advanced, proprietary technology developed at UNM that is now routinely capable of processing bioassays arrayed in 96-, 384- and 1536-well formats at throughputs of 60,000 or more wells per day. Key programs at UNMCMD include screening of research targets submitted by the international community through NIH’s Molecular Libraries Program; a multi-year effort involving translational partnerships at UNM directed towards drug repurposing - identifying new uses for clinically approved drugs; and a recently established personalized medicine initiative for advancing cancer therapy by the application of “smart” oncology drugs in selected patients based on response patterns of their cancer cells in vitro. UNMCMD discoveries, innovation, and translation have contributed to a wealth of inventions, patents, licenses and publications, as well as startup companies, clinical trials and a multiplicity of domestic and international collaborative partnerships to further the research enterprise. PMID:24409953

  5. The economic impact of Sandia National Laboratories on Central New Mexico and the State of New Mexico Fiscal Year 1998

    Energy Technology Data Exchange (ETDEWEB)

    Lansford, Robert R.; Adcock, Larry D.; Gentry, Lucille M.; Ben-David, Shaul; Temple, John

    1999-08-09

    Sandia National Laboratories (SNL) is a Department of Energy federally funded national security laboratory that uses engineering and science to ensure the security of the Nation. SNL provides scientific and engineering solutions to meet national needs in nuclear weapons and related defense systems, energy security, and environmental integrity. SNL works in partnerships with universities and industry to enhance their mission and transfer technology that will address emerging national challenges for both government and industry. For several years, the U.S. Department of Energy (DOE) Albuquerque Operations Office (AL) and New Mexico State University (NMSU) have maintained an inter-industry, input-output (I/O) model with capabilities to assess the impacts of developments initiated outside the economy such as federal DOE monies that flow into the state, on an economy. This model will be used to assess economic, personal income and employment impacts of SNL on Central New Mexico and the State of New Mexico. Caution should be exercised when comparing economic impacts between fiscal years prior to this report. The I/O model was rebased for FY 1998. The fringe benefits coefficients have been updated for the FY 1996 and FY 1997 economic impacts analysis. Prior to FY 1993 two different I/O base models were used to estimate the impacts. New technical information was released by the Bureau of Economic Analysis (BEA), U.S. Department of Commerce in 1991 and in 1994 and was incorporated in FY 1991, FY 1993, and FY 1994 I/O models. Also in 1993, the state and local tax coefficients and expenditure patterns were updated from a 1986 study for the FY 1992 report. Further details about the input-output model can be found in ''The Economic Impact of the Department of Energy on the State of New Mexico--FY 1998'' report by Lansford, et al. (1999). For this report, the reference period is FY 1998 (October 1, 1997, through September 30, 1998) and includes two major

  6. Openness initiative

    International Nuclear Information System (INIS)

    Duncan, S.S.

    1995-01-01

    Although antinuclear campaigns seem to be effective, public communication and education efforts on low-level radioactive waste have mixed results. Attempts at public information programs on low-level radioactive waste still focus on influencing public opinion. A question then is: open-quotes Is it preferable to have a program focus on public education that will empower individuals to make informed decisions rather than trying to influence them in their decisions?close quotes To address this question, a case study with both quantitative and qualitative data will be used. The Ohio Low-Level Radioactive Waste Education Program has a goal to provide people with information they want/need to make their own decisions. The program initiated its efforts by conducting a statewide survey to determine information needed by people and where they turned for that information. This presentation reports data from the survey and then explores the program development process in which programs were designed and presented using the information. Pre and post data from the programs reveal attitude and knowledge shifts

  7. Openness initiative

    Energy Technology Data Exchange (ETDEWEB)

    Duncan, S.S. [Los Alamos National Lab., NM (United States)

    1995-12-31

    Although antinuclear campaigns seem to be effective, public communication and education efforts on low-level radioactive waste have mixed results. Attempts at public information programs on low-level radioactive waste still focus on influencing public opinion. A question then is: {open_quotes}Is it preferable to have a program focus on public education that will empower individuals to make informed decisions rather than trying to influence them in their decisions?{close_quotes} To address this question, a case study with both quantitative and qualitative data will be used. The Ohio Low-Level Radioactive Waste Education Program has a goal to provide people with information they want/need to make their own decisions. The program initiated its efforts by conducting a statewide survey to determine information needed by people and where they turned for that information. This presentation reports data from the survey and then explores the program development process in which programs were designed and presented using the information. Pre and post data from the programs reveal attitude and knowledge shifts.

  8. Subsurface gas hydrates in the northern Gulf of Mexico

    Science.gov (United States)

    Boswell, Ray; Collett, Timothy S.; Frye, Matthew; Shedd, William; McConnell, Daniel R.; Shelander, Dianna

    2012-01-01

    The northernGulf of Mexico (GoM) has long been a focus area for the study of gashydrates. Throughout the 1980s and 1990s, work focused on massive gashydrates deposits that were found to form at and near the seafloor in association with hydrocarbon seeps. However, as global scientific and industrial interest in assessment of the drilling hazards and resource implications of gashydrate accelerated, focus shifted to understanding the nature and abundance of "buried" gashydrates. Through 2005, despite the drilling of more than 1200 oil and gas industry wells through the gashydrate stability zone, published evidence of significant sub-seafloor gashydrate in the GoM was lacking. A 2005 drilling program by the GoM GasHydrate Joint Industry Project (the JIP) provided an initial confirmation of the occurrence of gashydrates below the GoM seafloor. In 2006, release of data from a 2003 industry well in Alaminos Canyon 818 provided initial documentation of gashydrate occurrence at high concentrations in sand reservoirs in the GoM. From 2006 to 2008, the JIP facilitated the integration of geophysical and geological data to identify sites prospective for gashydrate-bearing sands, culminating in the recommendation of numerous drilling targets within four sites spanning a range of typical deepwater settings. Concurrent with, but independent of, the JIP prospecting effort, the Bureau of Ocean Energy Management (BOEM) conducted a preliminary assessment of the GoM gashydratepetroleum system, resulting in an estimate of 607 trillion cubic meters (21,444 trillion cubic feet) gas-in-place of which roughly one-third occurs at expected high concentrations in sand reservoirs. In 2009, the JIP drilled seven wells at three sites, discovering gashydrate at high saturation in sand reservoirs in four wells and suspected gashydrate at low to moderate saturations in two other wells. These results provide an initial confirmation of the complex nature and occurrence of gashydrate-bearing sands in

  9. Working without a Union in New Mexico

    Science.gov (United States)

    Adele, Niame; Rack, Christine

    2008-01-01

    In this article, the authors provide a description of the academic climate in New Mexico. Like many other places in the world today, New Mexico is trying to find an identity in an environment that the authors label "increasingly privatized, corporatized, and militarized." New Mexico's higher education salaries are lower than those in…

  10. New Mexico Charter Schools Annual Report

    Science.gov (United States)

    New Mexico Public Education Department, 2013

    2013-01-01

    In 2011, the New Mexico legislature passed changes to the Charter School Act that provided more accountability for both charters and authorizers in New Mexico. As part of that law, the Public Education Department (PED) is asked to submit an annual report on the status of charter schools in New Mexico. This is the first report submitted under that…

  11. California-Mexico gas exports eyed

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This paper reports that two California utilities have proposed providing natural gas transportation services to Mexico. The arrangement would provide a second U.S. export sales point at the U.S.-Mexico border and perhaps help alleviate an expected surplus of gas pipeline capacity available to California. Mexico currently imports about 200 MMcfd of U.S. gas via pipelines in Texas

  12. Digital Geologic Map of New Mexico - Formations

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The geologic map was created in GSMAP at Socorro, New Mexico by Orin Anderson and Glen Jones and published as the Geologic Map of New Mexico 1:500,000 in GSMAP...

  13. CERN servers go to Mexico

    CERN Multimedia

    Stefania Pandolfi

    2015-01-01

    On Wednesday, 26 August, 384 servers from the CERN Computing Centre were donated to the Faculty of Science in Physics and Mathematics (FCFM) and the Mesoamerican Centre for Theoretical Physics (MCTP) at the University of Chiapas, Mexico.   CERN’s Director-General, Rolf Heuer, met the Mexican representatives in an official ceremony in Building 133, where the servers were prepared for shipment. From left to right: Frédéric Hemmer, CERN IT Department Head; Raúl Heredia Acosta, Deputy Permanent Representative of Mexico to the United Nations and International Organizations in Geneva; Jorge Castro-Valle Kuehne, Ambassador of Mexico to the Swiss Confederation and the Principality of Liechtenstein; Rolf Heuer, CERN Director-General; Luis Roberto Flores Castillo, President of the Swiss Chapter of the Global Network of Qualified Mexicans Abroad; Virginia Romero Tellez, Coordinator of Institutional Relations of the Swiss Chapter of the Global Network of Qualified Me...

  14. Health technology assessment in Mexico.

    Science.gov (United States)

    Gómez-Dantés, Octavio; Frenk, Julio

    2009-07-01

    The history of health technology assessment (HTA) in Mexico is examined, starting with the efforts to incorporate this topic into the policy agenda and culminating with the recent creation of a specialized public agency. Information was gathered through a bibliographic search and interviews with actors involved in HTA in Mexico. HTA efforts were developed in Mexico since the mid-1980s with the participation both of academics and of policy makers, a relationship that eventually led to the creation of the Center for Technological Excellence within the Ministry of Health. Institutionalization of HTA in resource-constrained settings requires the development of a critical mass of researchers involved in this field, the implementation of information efforts, and the establishment of strong relationships between HTA experts and policy makers.

  15. New Mexico low-temperature geothermal resources and economic development programs

    International Nuclear Information System (INIS)

    Whittier, J.; Schoenmackers, R.

    1990-01-01

    This paper reports on New Mexico's low-temperature geothermal resources which have been utilized to promote economic development initiatives within the state. Public funds have been leveraged to foster exploration activities which have led to the establishment of several direct-use projects at various sites within New Mexico. State policies have focused on attracting one business sector, the commercial greenhouse industry, to expand and/or relocate in New Mexico. Geothermal-related promotional activities have begun to show success in achieving economic growth. New Mexico now has almost half of the geothermally-heated greenhouse space in the nation. It is anticipated that the greenhouse sector will continue to grow within the state. Future economic development activities, also relying upon the geothermal resource base, will include vegetable dehydration and aquaculture with a focus on the microalgae sector

  16. Country watch: Mexico.

    Science.gov (United States)

    San Miguel Aguirre, E

    1997-01-01

    This article describes the program activities of the Mexican National Commission on Human Rights (CNDH), which in 1994 created a program to address human rights issues of HIV-infected victims. The aim was to answer complaints of discrimination against HIV-infected persons and to modify confrontational attitudes of groups that feel infringed upon by the rights of HIV-infected persons. CNDH formed a task force of HIV/AIDS medical experts, which recommended actions for three types of discriminatory practices. Persons with HIV/AIDS (PWHA) who were confined in prison filed complaints about the lack of necessary medications or medical attention. The Official Mexican Norm for the Prevention and Control of HIV stipulates, in its Manual for the Attention of Complaints Regarding HIV/AIDS, protocols for treatment of PWHA. This manual was distributed to 31 State Human Rights Commissions in Mexico. CNDH implemented an outreach program to educate the public about HIV/AIDS, to offer training courses, and to publish written materials about discrimination against PWHA. The CNDH conducted conferences and training sessions for workers in the health services, where most violations of human rights take place. CNDH works closely with the National Board for the Prevention and Control of AIDS to assess clinical records, train staff handling complaints, and channel complaints that require CNDH intervention. CNDH conducts training workshops for nongovernmental organizations. CNDH is constrained by bureaucratic procedures that slow the process of resolving complaints and by the small CNDH staff responsible for handling the more complex cases. However, CNDH has successfully resolved a number of complaints and improved the prison conditions of PWHA.

  17. Antiproton Target

    CERN Multimedia

    1980-01-01

    Antiproton target used for the AA (antiproton accumulator). The first type of antiproton production target used from 1980 to 1982 comprised a rod of copper 3mm diameter and 120mm long embedded in a graphite cylinder that was itself pressed into a finned aluminium container. This assembly was air-cooled and it was used in conjunction with the Van der Meer magnetic horn. In 1983 Fermilab provided us with lithium lenses to replace the horn with a view to increasing the antiproton yield by about 30%. These lenses needed a much shorter target made of heavy metal - iridium was chosen for this purpose. The 50 mm iridium rod was housed in an extension to the original finned target container so that it could be brought very close to the entrance to the lithium lens. Picture 1 shows this target assembly and Picture 2 shows it mounted together with the lithium lens. These target containers had a short lifetime due to a combination of beam heating and radiation damage. This led to the design of the water-cooled target in...

  18. Designing Distributed Generation in Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Linvill, Carl [Regulatory Assistance Project, Montepelier, VT (United States); Brutkoski, Donna [Regulatory Assistance Project, Montepelier, VT (United States)

    2017-05-15

    Mexico's energy reform will have far-reaching effects on how people produce and consume electricity in the country. Market liberalization will open the door to an increasing number of options for Mexican residential, commercial, and industrial consumers, and distributed generation (DG), which for Mexico includes generators of less than 500 kilowatts (kW) of capacity connected to the distribution network. Distributed generation is an option for consumers who want to produce their own electricity and provide electricity services to others. This report seeks to provide guidance to Mexican officials on designing DG economic and regulatory policies.

  19. New Mexico Geothermal Data Base

    International Nuclear Information System (INIS)

    Witcher, J.C.; Whittier, J.; Morgan, R.

    1990-01-01

    This paper reports on the New Mexico Geothermal Data Base (NMGDB) which is a comprehensive public-domain data base of low-temperature geothermal resource information for New Mexico that is designed to assist researchers and developers. A broad range of geoscience, engineering, climatic, economic, and land status information are complied in the dBASE III PLUS data base management system for use on an IBM or IBM-compatible personal computer. A user friendly menu format with on-screen prompts allows easy and convenient use

  20. Barriers to treatment access for Chagas disease in Mexico.

    Science.gov (United States)

    Manne, Jennifer M; Snively, Callae S; Ramsey, Janine M; Salgado, Marco Ocampo; Bärnighausen, Till; Reich, Michael R

    2013-01-01

    According to World Health Organization (WHO) prevalence estimates, 1.1 million people in Mexico are infected with Trypanosoma cruzi, the etiologic agent of Chagas disease (CD). However, limited information is available about access to antitrypanosomal treatment. This study assesses the extent of access in Mexico, analyzes the barriers to access, and suggests strategies to overcome them. Semi-structured in-depth interviews were conducted with 18 key informants and policymakers at the national level in Mexico. Data on CD cases, relevant policy documents and interview data were analyzed using the Flagship Framework for Pharmaceutical Policy Reform policy interventions: regulation, financing, payment, organization, and persuasion. Data showed that 3,013 cases were registered nationally from 2007-2011, representing 0.41% of total expected cases based on Mexico's national prevalence estimate. In four of five years, new registered cases were below national targets by 11-36%. Of 1,329 cases registered nationally in 2010-2011, 834 received treatment, 120 were pending treatment as of January 2012, and the treatment status of 375 was unknown. The analysis revealed that the national program mainly coordinated donation of nifurtimox and that important obstacles to access include the exclusion of antitrypanosomal medicines from the national formulary (regulation), historical exclusion of CD from the social insurance package (organization), absence of national clinical guidelines (organization), and limited provider awareness (persuasion). Efforts to treat CD in Mexico indicate an increased commitment to addressing this disease. Access to treatment could be advanced by improving the importation process for antitrypanosomal medicines and adding them to the national formulary, increasing education for healthcare providers, and strengthening clinical guidelines. These recommendations have important implications for other countries in the region with similar problems in access to

  1. [The treatment received by public health services users in Mexico].

    Science.gov (United States)

    Puentes Rosas, Esteban; Gómez Dantés, Octavio; Garrido Latorre, Francisco

    2006-06-01

    To document the fact that differences in the treatment received by health services users in Mexico are mainly dependent on the type of provider, regardless of the users' socioeconomic status. The data were obtained by means of a survey of 18 018 users who visited 73 health services in 13 states within Mexico. They were asked to grade the way the institution had performed in seven of the eight domains that define appropriate user treatment (autonomy, confidentiality, communication, respectful manner, condition of basic facilities, access to social assistance networks, and free user choice). The questionnaire included some vignettes to help determine user expectations. A composite ordinal probit model was applied; the perception of quality in connection with each of the appropriate treatment domains was the independent variable, whereas gender, educational level, age, type of provider, and user expectations were used as control variables. The type of provider was the main factor that determined users' perceptions regarding the treatment they received when visiting health services in Mexico. Institutions belonging to the social security system performed the worst, while the services provided under the program targeting the rural population (IMSS Oportunidades) received the highest scores. Overall, the domain that was most highly ranked was respectful manner, whereas the lowest score was given to the ability to choose the provider. Men felt they had been able to communicate better than women, while respectful manner, communication, and social support showed a significant negative association with educational level (P < 0.05). Differences were noted in the way different public health service providers in Mexico treat their users, regardless of the latter's socioeconomic status. Social security system providers showed the greatest deficiencies in this respect. Respectful manner was the domain that received the highest scores in the case of all providers. Organizational

  2. Las Tierras de Nuevo Mexico. [The Lands of New Mexico.

    Science.gov (United States)

    Swadesh, Frances Leon; And Others

    New Mexico was inhabited thousands of years ago. Each group of settlers saw the land in distinct ways. For some, its beauty consisted of its quality, the abundance of water, and the hope of a good harvest. For others, its beautiful sites were of more importance. Thus, each group established its own manner of living on the land and of using it.…

  3. Interactions between the Laramide Foreland and the passive margin of the Gulf of Mexico: Tectonics and sedimentation in the Golden Lane area, Veracruz State, Mexico

    NARCIS (Netherlands)

    Alzaga-Ruiz, H.; Lopez, M.; Roure, F.; Séranne, M.

    2009-01-01

    This paper focuses on the analyses of the clastic sedimentary infill of the Coastal Plain of Eastern Mexico, which initiated synchronously with the Laramide orogeny in the vicinity of the Golden Lane. Results of these analyses are used as boundary conditions for calibrating/interpreting seismic

  4. Community Rates of Breastfeeding Initiation.

    Science.gov (United States)

    Grubesic, Tony H; Durbin, Kelly M

    2016-11-01

    Breastfeeding initiation rates vary considerably across racial and ethnic groups, maternal age, and education level, yet there are limited data concerning the influence of geography on community rates of breastfeeding initiation. This study aimed to describe how community rates of breastfeeding initiation vary in geographic space, highlighting "hot spots" and "cool spots" of initiation and exploring the potential connections between race, socioeconomic status, and urbanization levels on these patterns. Birth certificate data from the Kentucky Department of Health for 2004-2010 were combined with county-level geographic base files, Census 2010 demographic and socioeconomic data, and Rural-Urban Continuum Codes to conduct a spatial statistical analysis of community rates of breastfeeding initiation. Between 2004 and 2010, the average rate of breastfeeding initiation for Kentucky increased from 43.84% to 49.22%. Simultaneously, the number of counties identified as breastfeeding initiation hot spots also increased, displaying a systematic geographic pattern in doing so. Cool spots of breastfeeding initiation persisted in rural, Appalachian Kentucky. Spatial regression results suggested that unemployment, income, race, education, location, and the availability of International Board Certified Lactation Consultants are connected to breastfeeding initiation. Not only do spatial analytics facilitate the identification of breastfeeding initiation hot spots and cool spots, but they can be used to better understand the landscape of breastfeeding initiation and help target breastfeeding education and/or support efforts.

  5. Juvenile Justice in Mexico

    Directory of Open Access Journals (Sweden)

    Martha Frías Armenta

    2014-08-01

    Full Text Available The first tribunal in Mexico was established in the central state of San Luis Potosi in 1926. The Law Regarding Social Prevention and Juvenile Delinquency for the Federal District and Mexican territories was promulgated in 1928. In 2005, Article 18 of the Mexican Constitution was modified to establish a comprehensive system (“Sistema Integral de justicia” in Spanish of justice for juveniles between 12 and 18 years old who had committed a crime punishable under criminal law. Its objective was to guarantee juveniles all the due process rights established for adults, in addition to the special ones recognized for minors. The constitutional reform also provides a framework that includes special tribunals as well as alternative justice options for juveniles. With these reforms, institutionalization of minors was to be considered an extreme measure applicable only to felonies and to juveniles older than 14. In 2006, all states within the Mexican federation enacted the “Law of justice for adolescents”. This system, at both the federal and state levels, formalizes a new global paradigm with regard to the triangular relationship between children, the State and the Law. It recognizes that children are also bearers of the inherent human rights recognized for all individuals, instead of simply objects in need of protection. However, despite formally aligning Mexican juvenile justice law with the Convention on the Rights of the Child (CRC, issues of actual substantive rights remained and new ones have appeared. For example, juveniles younger than 14 who have not committed a felony are released from institutions without any rehabilitation or treatment options, and alternative forms of justice were included without evaluating their possibilities of application or their conditions for success. In addition, the economic status of most juvenile detainees continues to be one of the most important determining factors in the administration of justice

  6. Mexico: The Accidental Narco?

    Science.gov (United States)

    2011-06-30

    9 Gonzales, Maria de la Luz (2009-03-25). "Suman 10 mil 475 ejecuciones en esta administracion : PGR" (in Spanish). El Universal. http...the Sinaloa cartel, Ignacio Coronel was killed in 2010. The leader of La Familia, Nazario Moreno Gonzalez, could not escape the reach of Mexican...cartel, La Familia, had proposed truces with the government and promised a reduction in violence if the government focuses more on targeting its

  7. The MEGAPIE Initiative

    International Nuclear Information System (INIS)

    Salvatores, M.; Bauer, G.S.; Heusener, G.

    2000-10-01

    MEGAPIE (Megawatt Pilot Experiment) is a joint initiative by Commissariat a l'Energie Atomique (CEA), France, Forschungszentrum Karlsruhe (FZK), Germany, and Paul Scherrer Institut (PSI), Switzerland, to design, build, operate and explore a liquid lead-bismuth spallation target for 1MW of beam power, taking advantage of the existing spallation neutron facility SINQ at PSI. Such a target based on an eutectic mixture with a melting point as low as 125 o C and a boiling point as high as 1670 o C is the preferred concept in several studies aiming at utilising accelerators to drive subcritical assemblies in order to transmute long lived nuclear waste into shorter lived isotopes in an effort to ease problems of long term storage and final disposal. MEGAPIE will be an essential step towards demonstrating the feasibility of the coupling of a high power accelerator, a spallation target and a subcritical assembly. It will specifically address one of the most critical issues, namely the behaviour of a liquid metal target under realistic operating conditions. As an intensely instrumented pilot experiment it will provide valuable data for benchmarking of frequently used computer codes and will allow to gain important experience in the safe handling of components that have been irradiated with PbBi. It will be installed at the ring cyclotron at PSI with 590 MeV proton energy and a continuous current of 1.8 mA. The basic concept of the MEGAPIE target as well as the definition of the project phases and of the supporting research and development activities at the participating laboratories are described in the present report

  8. ( Didelphis virginiana ) from Yucatan, Mexico

    African Journals Online (AJOL)

    Toxoplasma gondii is an obligate intracellular parasite recognized as a causal agent of toxoplasmosis; zoonotic disease endemic in many countries worldwide, including Mexico. Different species of animals participate in the wild cycle infection, including opossums of the species Didelphis virginiana. Thirteen D. virginiana ...

  9. Radioactive waste management in Mexico

    International Nuclear Information System (INIS)

    Paredes, L.; Reyes L, J.; Jimenez D, J.

    2000-01-01

    This paper describes the radioactive waste management in Mexico, particularly the activities that the National Institute of Nuclear Research (NINR) is undertaking in this field. Classification and annual generation of radioactive waste, together with practices and facilities relating to the management of radioactive waste are addressed. The respective national legal framework and policy are outlined. (author)

  10. Shell Trumpets from Western Mexico

    Directory of Open Access Journals (Sweden)

    Robert Novella

    1991-11-01

    Full Text Available Marine shells have been used as musical instruments in almost all parts of the world (Izikowitz 1935, including Mesoamerica, where large univalves, also called conch shells in the literature, had a utilitarian function as trumpets. Their use is well documented in most cultural areas of Mesoamerica, as in Western Mexico, through their various occurrences in archaeological contexts and museums collections.

  11. Pemex and Mexico's mixed emotions

    International Nuclear Information System (INIS)

    Dombey, D.

    1997-01-01

    Pemex, Mexico's state owned oil company, has long been a byword for overmanning, inefficiency, disregard for the environment and for having all the ills of state incorporation, with few of the benefits. Matters, however, are changing. Pemex wants to be normal. (author)

  12. Alternative Education Spaces in Mexico

    Science.gov (United States)

    Gray, Chloe

    2010-01-01

    This article explores the architecture of the Red de Innovacion y Aprendizaje (RIA), or Learning and Innovation Network, which is a group of education centres that provide access to computers, the Internet and quality education to low-income communities in Mexico. The RIA began in May 2009 when ten pilot centres were opened in four municipalities…

  13. Mexico: swapping crude for atoms

    International Nuclear Information System (INIS)

    Navarro, B.

    1982-01-01

    Mexico, considered the Saudi Arabia of the Western Hemisphere because of its proven and potential petroleum reserves, has surprised the world: it has embarked on the biggest nuclear-electric program in the Third World, only to postpone it days before scheduled approval of an international bidding (on which the atomic energy industry had pinned its hopes). A graph shows Mexican supplies of electricity by source with official projections to 1990. The point of entrance of the first nuclear reactor, originally scheduled for 1982, won't come onstream until 1983; and how nuclear-generated electricity grows close to 5% of the total in 1990. The big question is, will the future President of Mexico give the green light to the atomic megaproject. And if he does, how will Mexico deal with the serious logistics problems and grave ecological implications confronting the industry worldwide. In this issue, the author and Energy Detente touch on these questions and review the nuclear power status of Mexico, as well as addressing some of its global problems. Also presented in this issue is an update of the fuel price/tax series for the Western Hemisphere countries

  14. Village Dogs in Coastal Mexico

    NARCIS (Netherlands)

    Ruiz Izaguirre, Eliza; Hebinck, P.G.M.; Eilers, C.H.A.M.

    2018-01-01

    Village dogs are important for households in coastal Mexico, yet they are seen as out of place by etic stakeholders (public health and wildlife experts, and animal welfarists). Caregivers of village dogs are considered irresponsible, a view that is reinforced by Mexican policy. We describe two

  15. Structural Damage in Mexico City

    OpenAIRE

    Hall, John F.; Beck, James L.

    1986-01-01

    This paper describes the structural damage in Mexico City caused by the September 19, 1985 earthquake. Photographs which illustrate various features of structural behavior are included. One explanation is presented as to why buildings with fundamental periods of elastic vibration considerably below the predominant two‐second period of the ground motion were most vulnerable to damage.

  16. "Mexico in Transition." Curriculum Units.

    Science.gov (United States)

    Oregon Univ., Eugene. Foreign Language Resource Center.

    These curriculum units were developed in a National Endowment for the Humanities 1994 summer seminar "Mexico in Transition." The 23 lessons are written in Spanish. Lessons are entitled: (1) "La Migracion Mexicana Vista a Traves del Cuento 'Paso del Norte' de Juan Rulfo" (Jose Jorge Armendariz); (2) "Los Grupos Indigenas de…

  17. Lighting the city. First poetic representations of Mexico City

    Directory of Open Access Journals (Sweden)

    Claudia Kerik

    2018-01-01

    Full Text Available The first impressions that caused the changes made in Mexico City in its process of transformation into a modern city were captured by its poets drawing attention to different aspects of life in the capital. While from the popular poetry the record of the entrance of the electricity in the public road was left, from the official poetry was tried to witness the new cosmopolitan status of the Mexico City in the Porfirian era, through the fashion and the customs that were revealed in one of the main streets of the city. Comparing these poems allows us to know the initial strategies of poetic figuration of urban space that will continue to develop along different paths throughout the twentieth century until we reach our days.

  18. Study of Grants, new Mexico, uranium miners: current status

    International Nuclear Information System (INIS)

    Samet, J.M.; Morgan, M.V.; Buechley, R.W.; Key, C.R.; Valdivia, A.A.

    1981-01-01

    The Uranium Epidemiology Study at the University of New Mexico was initiated in 1977 with the objective of assessing health effects of uranium mining in the Grants, New Mexico, area. The planned approach was a cohort study of mortality that would capitalize on the availability of health records at the Grants Clinic. The first year's work confirmed the study's feasibility (Buechley, 1979). Subsequent efforts have focused on the health and exposure data base and comprehensive follow-up. A retrospective cohort study of early miners is in progress; a prospective cohort study of miners who began working under the current federal standard is planned. This report will summarize the current status of the Uranium Epidemiology Study

  19. External Police Oversight in Mexico: Experiences, Challenges, and Lessons Learned

    Directory of Open Access Journals (Sweden)

    Rubén Guzmán Sánchez

    2014-11-01

    Full Text Available After nearly 20 years of ‘reformist’ measures, the police in Mexico continues to be an ineffective, unreliable, and ‘far from citizen’ institution. The efforts made so far have faded amongst political interests and agendas; multidimensional frameworks out-dated at both conceptual and interagency levels; short-sighted competition for resources; evaluation and performance monitors that are handicapped by bureaucratic inaction; and weak transparency and accountability that perpetuate the opacity in which the police operate. In this context, the agenda of external police oversight is still at a rudimentary stage. However, there are several initiatives that have managed to push the issue to the frontier of new knowledge and promising practices. This paper outlines the experiences and challenges of—as well as the lessons learned by—the Institute for Security and Democracy (Insyde A.C., one of the most recognised think tanks in Mexico.

  20. Aerobiology of Juniperus Pollen in Oklahoma, Texas, and New Mexico

    Science.gov (United States)

    Levetin, Estelle; Bunderson, Landon; VandeWater, Pete; Luvall, Jeff

    2014-01-01

    Pollen from members of the Cupressaceae are major aeroallergens in many parts of the world. In the south central and southwest United States, Juniperus pollen is the most important member of this family with J. ashei (JA) responsible for severe winter allergy symptoms in Texas and Oklahoma. In New Mexico, pollen from J. monosperma (JM) and other Juniperus species are important contributors to spring allergies, while J. pinchotii (JP) pollinates in the fall affecting sensitive individuals in west Texas, southwest Oklahoma and eastern New Mexico. Throughout this region, JA, JM, and JP occur in dense woodland populations. Generally monitoring for airborne allergens is conducted in urban areas, although the source for tree pollen may be forested areas distant from the sampling sites. Improved pollen forecasts require a better understanding of pollen production at the source. The current study was undertaken to examine the aerobiology of several Juniperus species at their source areas for the development of new pollen forecasting initiatives.

  1. Efficacy of melflufen, a peptidase targeted therapy, and dexamethasone in an ongoing open-label phase 2a study in patients with relapsed and relapsed-refractory multiple myeloma (RRMM) including an initial report on progression free survival

    DEFF Research Database (Denmark)

    Voorhees, P. M.; Magarotto, V.; Sonneveld, P.

    2015-01-01

    to DNA or is readily metabolized by intracellular peptidases into hydrophilic alkylating metabolites. With targeted delivery of alkylating metabolites to tumor cells in vitro (such as multiple myeloma that are rich in activating peptidase), melflufen exerts a 20-100 fold higher anti-tumor potency...... and produces a 20 fold higher intracellular concentration of alkylating moieties compared with melphalan. Methods: Melflufen is evaluated in combination with dexamethasone (dex) 40 mg weekly in an ongoing Phase 1/2a study. RRMM patients with measurable disease and at least 2 prior lines of therapy are eligible......%) and constipation and epistaxis (13%). Treatment-related Grade 3 or 4 AEs were reported in 27 patients (87%). Those occurring in >5% of patients were thrombocytopenia (68%), neutropenia (55%), anemia (42%), leukopenia (32%) and febrile neutropenia, fatigue, pyrexia, asthenia and hyperglycemia each occurred in 6...

  2. 9 CFR 93.427 - Cattle from Mexico.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Cattle from Mexico. 93.427 Section 93... CONVEYANCE AND SHIPPING CONTAINERS Ruminants Mexico 10 § 93.427 Cattle from Mexico. (a) Cattle and other ruminants imported from Mexico, except animals being transported in bond for immediate return to Mexico or...

  3. 7 CFR 319.8-13 - From Northwest Mexico.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false From Northwest Mexico. 319.8-13 Section 319.8-13... for the Entry of Cotton and Covers from Mexico § 319.8-13 From Northwest Mexico. Contingent upon continued freedom of Northwest Mexico and of the West Coast of Mexico from infestations of the pink bollworm...

  4. GRIIDC: A Data Repository for Gulf of Mexico Science

    Science.gov (United States)

    Ellis, S.; Gibeaut, J. C.

    2017-12-01

    The Gulf of Mexico Research Initiative Information & Data Cooperative (GRIIDC) system is a data management solution appropriate for any researcher sharing Gulf of Mexico and oil spill science data. Our mission is to ensure a data and information legacy that promotes continual scientific discovery and public awareness of the Gulf of Mexico ecosystem. GRIIDC developed an open-source software solution to manage data from the Gulf of Mexico Research Initiative (GoMRI). The GoMRI program has over 2500 researchers from diverse fields of study with a variety of attitudes, experiences, and capacities for data sharing. The success of this solution is apparent through new partnerships to share data generated by RESTORE Act Centers of Excellence Programs, the National Academies of Science, and others. The GRIIDC data management system integrates dataset management planning, metadata creation, persistent identification, and data discoverability into an easy-to-use web application. No specialized software or program installations are required to support dataset submission or discovery. Furthermore, no data transformations are needed to submit data to GRIIDC; common file formats such as Excel, csv, and text are all acceptable for submissions. To ensure data are properly documented using the GRIIDC implementation of the ISO 19115-2 metadata standard, researchers submit detailed descriptive information through a series of interactive forms and no knowledge of metadata or xml formats are required. Once a dataset is documented and submitted the GRIIDC team performs a review of the dataset package. This review ensures that files can be opened and contain data, and that data are completely and accurately described. This review does not include performing quality assurance or control of data points, as GRIIDC expects scientists to perform these steps during the course of their work. Once approved, data are made public and searchable through the GRIIDC data discovery portal and the Data

  5. Targeted Learning

    CERN Document Server

    van der Laan, Mark J

    2011-01-01

    The statistics profession is at a unique point in history. The need for valid statistical tools is greater than ever; data sets are massive, often measuring hundreds of thousands of measurements for a single subject. The field is ready to move towards clear objective benchmarks under which tools can be evaluated. Targeted learning allows (1) the full generalization and utilization of cross-validation as an estimator selection tool so that the subjective choices made by humans are now made by the machine, and (2) targeting the fitting of the probability distribution of the data toward the targe

  6. Target preparation

    International Nuclear Information System (INIS)

    Hinn, G.M.

    1984-01-01

    A few of the more interesting of the 210 targets prepared in the Laboratory last year are listed. In addition the author continues to use powdered silver mixed with /sup 9,10/BeO to produce sources for accelerator radio dating of Alaskan and South Polar snow. Currently, he is trying to increase production by multiple sample processing. Also the author routinely makes 3 μg/cm 2 cracked slacked carbon stripper foils and is continuing research with some degree of success in making enriched 28 Si targets starting with the oxide

  7. Considerations to the nuclear safety in Mexico; Consideraciones a la seguridad nuclear en Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Salas M, B. [UNAM, Facultad de Ciencias, Departamento de Fisica, Laboratorio de Analisis Radiologicos de Muestras Ambientales, Ciudad Universitaria, 04510 Mexico D.F. (Mexico)]. e-mail: salasmarb@yahoo.com.mx

    2006-07-01

    The uncertain future of the hydrocarbons like main source of energy, force us to think on the nuclear energy as the suitable substitute that we can inherit to those future generations. Mexico therefore should multiply the number of nuclear power centrals and to be in this way prepared for the new challenges, however, it is necessary and advisable, to restate the mexican nuclear plan that includes mainly the transparency. The 'WANO Report' (World Association of Nuclear Operators - for their initials in English), result of a technical audit to the Nuclear Power station of Laguna Verde (CNLV), it is a polemic topic, because in accordance with David Lochbaum of 'The Union of Concerned Scientists' of the United States of America and of John Large of 'Large and Associates' of the Great Britain, the security in the CNLV is questionable. The pronouncements of concern of Abel J. Gonzalez and Ken E. Brockman, high officials of the International Atomic Energy Agency who took knowledge of diverse irregularities in the CNLV, should be analysis reason for to take actions in pro of the future of the nuclear energy in Mexico. (Author)

  8. Laser targets: introduction

    International Nuclear Information System (INIS)

    Rosen, M.D.

    1985-01-01

    The laser target design group was engaged in three main tasks in 1984: (1) analyzing Novette implosion and hohlraum-scaling data, (2) planning for the first experiments on Nova, and (3) designing laboratory x-ray laser targets and experiments. The Novette implosion and hohlraum scaling data are mostly classified and are therefore not discussed in detail here. The authors achieved average final/initial pusher pr ratios of about 50, some 3 times higher than the value achieved in the best Shiva shots. These pr values imply a fuel compression to 100 times liquid density, although this figure and other aspects of the experiments are subject to further interpretation because of detailed questions of target symmetry and stability. Their main long-term goal for Nova is to produce a so-called hydrodynamically equivalent target (HET) - that is, a target whose hydrodynamic behavior (implosion velocity, convergence ratio, symmetry and stability requirements, etc.) is very much like that of a high-gain target, but one that is scaled down in size to match the energy available from Nova and is too small to achieve enough hot-spot pr to ignite the cold, near-Fermi-degenerate fuel around it. Their goal for Nova's first year is to do experiments that will teach them how to achieve the symmetry and stability conditions required by an HET

  9. Deepwater Horizon - baseline fisheries surveys conducted in the Gulf of Mexico from 1987-04-16 to 2010-08-01 (NCEI Accession 0150631)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In 2010, the Deepwater Horizon oil spill occurred in the Gulf of Mexico and the Natural Resources Damage Assessment (NRDA) was initiated to determine the extent of...

  10. Analysis of bluetooth and wi-fi technology to measure wait times of personal vehicles at Arizona-Mexico ports of entry : [executive summary].

    Science.gov (United States)

    2015-11-01

    The Arizona Department of Transportation (ADOT), Office of P3 Initiatives and International : Affairs selected Lee Engineering to analyze the penetration rate of Anonymous Re-Identification : (ARID) technology to measure wait time of U.S. and Mexico ...

  11. Initiative for safe driving and enhanced utilization of crash data

    Science.gov (United States)

    Wagner, John F.

    1994-03-01

    This initiative addresses the utilization of current technology to increase the efficiency of police officers to complete required Driving Under the Influence (DUI) forms and to enhance their ability to acquire and record crash and accident information. The project is a cooperative program among the New Mexico Alliance for Transportation Research (ATR), Science Applications International Corporation (SAIC), Los Alamos National Laboratory, and the New Mexico State Highway and Transportation Department. The approach utilizes an in-car computer and associated sensors for information acquisition and recording. Los Alamos artificial intelligence technology is leveraged to ensure ease of data entry and use.

  12. Mexico City air quality: Progress of an international collaborative project to define air quality management options

    International Nuclear Information System (INIS)

    Streit, G.E.

    1992-01-01

    Mexico City, faces a severe air pollution problem due to a combination of circumstances. The city is in a high mountain basin at a subtropical latitude. The basin setting inhibits dispersion of pollution and contributes to frequent wintertime thermal inversions which further trap pollutants near the surface. The elevation and latitude combine to provide plentiful sunshine which, in comparison to more northern latitudes, is enhanced in the UV radiation which drives atmospheric photochemistry to produce secondary pollutants such as ozone. The Area Metropolitana de la Ciudad de Mexico AMCW is defined to include the 16 delegations of the Federal District (D.F.) and 17 highly urbanized municipalities in the State of Mexico which border the D.F. The 1990 census (XI Censo General de Poblacion y Vivienda de 1990) records that slightly over 15 million people live in the AMCM. There are numerous other nearby communities which are in the airshed region of Mexico City, but which are not included in the definition and population of the AMCM. The Mexico City Air Quality Research Initiative is one project that is examining the complex relationship between air pollution, economic growth, societal values, and air quality management policies. The project utilizes a systems approach including computer modeling, comprehensive measurement studies of Mexico City's air pollutants, environmental chemical reaction studies and socioeconomic analysis. Los Alamos National Laboratory (USA) and the Mexican Petroleum Institute are the designated lead institutions

  13. 76 FR 64248 - Gulf of Mexico Reef Fish Fishery; Closure of the 2011 Gulf of Mexico Commercial Sector for...

    Science.gov (United States)

    2011-10-18

    .... 040205043-4043-01] RIN 0648-XA766 Gulf of Mexico Reef Fish Fishery; Closure of the 2011 Gulf of Mexico... the commercial sector for greater amberjack in the exclusive economic zone (EEZ) of the Gulf of Mexico... Reef Fish Resources of the Gulf of Mexico (FMP). The FMP was prepared by the Gulf of Mexico Fishery...

  14. Mexico and the CTBT; Mexico y el CTBT

    Energy Technology Data Exchange (ETDEWEB)

    Aguirre G, J.; Martinez L, J.; Ruiz E, L. J.; Aragon M, I. B., E-mail: jaguirre@cnsns.gob.mx [Comision Nacional de Seguridad Nuclear y Salvaguardias, Dr. Barragan 779, Col. Narvarte, 03020 Mexico D. F. (Mexico)

    2013-10-15

    The Comprehensive Nuclear Test-Ban-Treaty (CTBT) is a treaty that prohibits all the nuclear explosions by anybody and in any place, either on the terrestrial surface, in the atmosphere, under the sea or underground. From the adoption of this Treaty by the United Nations, Mexico has had interest for its entrance in vigor, as integral part to assure the international peace. For this reason, our country signed the Treaty since it was open in September 24, 1996 and three years later ratified it, due to Mexico is part of the group of necessary countries for their entrance in vigor. During 13 years, the country has been committed and helped to the installation of monitoring stations, actions that allow the strengthening of the International System of Surveillance. The purpose of this work is to divulge the Treaty,its technologies and benefits; and also to diffuse the works realized by Mexico regarding the radionuclides monitoring station and noble gases both certified ones for the CTBT. Besides the radionuclides technology, Mexico has taken charge of the installation and operation of the seismic stations and hydro-acoustics that have been certified too. The radionuclides station Rn-44 located in Guerrero Negro, BCS has two technologies, an automated sampler of suspended particles in air brand Cinderella/ARAME and a noble gases system Sauna used for the particles detection of radioactive material gamma emitting and Xenon radioisotopes product of nuclear assays. Both technologies are transmitting data in real time to the International Center of Data. These technologies are shown in this work. (Author)

  15. Pharmacies, communication, and condoms. Research report: Mexico.

    Science.gov (United States)

    Pick De Weiss, S

    1995-01-01

    The Institute Mexicano de Investigacion de Familia y Poblacion, A.C. (IMIFAP) tested the effectiveness of a training course and educational materials that were designed to increase the awareness and knowledge of pharmacy employees concerning acquired immunodeficiency syndrome (AIDS) and its prevention, and to promote condoms. 174 employees participated in workshops that included information on transmission and prevention of sexually transmitted diseases (STDs) and AIDS, and condom usage. Pre- and post-session tests were performed to ascertain the short-term retention of information; the long-term effect was assessed via incognito shopper visits and monitoring of condom sales. Short, intensive training, when reinforced by posters, pamphlets, and video, significantly increased knowledge of AIDS (symptoms, transmission, and prevention) and correct condom usage. Awareness of risk behaviors and groups at risk for AIDS improved. Printed materials alone did not have a substantial impact on knowledge or sales of condoms, and increased knowledge alone did not increase information disseminated. After 6 months there was a significantly higher rise in condom sales (16%) in the course-plus-materials group. This group also took a greater initiative in providing information to clients. In spite of these positive results, knowledge and initiative are still unsatisfactory, especially when the role of pharmacies in general health care and the suspected prevalence of sexually transmitted diseases and human immunodeficiency virus in Mexico are considered.

  16. Georeferenced Population Datasets of Mexico (GEO-MEX): Urban Place GIS Coverage of Mexico

    Data.gov (United States)

    National Aeronautics and Space Administration — The Urban Place GIS Coverage of Mexico is a vector based point Geographic Information System (GIS) coverage of 696 urban places in Mexico. Each Urban Place is...

  17. A report on the indoor residual spraying (IRS) in the control of Phlebotomus argentipes, the vector of visceral leishmaniasis in Bihar (India): an initiative towards total elimination targeting 2015 (Series-1).

    Science.gov (United States)

    Kumar, V; Kesari, S; Dinesh, D S; Tiwari, A K; Kumar, A J; Kumar, R; Singh, V P; Das, P

    2009-09-01

    Visceral leishmaniasis, commonly known as kala-azar is endemic in Bihar state, India. Current vector control programme in Bihar focuses mainly on spraying the sandfly infested dwellings with DDT. The Government of India in collaboration with WHO has fixed the target 2015 for total elimination of kala-azar. The present study was carried out to see the impact of DDT and improved IEC in the containment of vector density vis-à-vis disease transmission. Before the start of the spraying operations training was imparted to all the medical and paramedical personnel regarding the methods of spraying operations. Pre- and post-sandfly density was monitored in four selected districts. Incidences of kala-azar cases were compared for pre- and post-spray periods. Social acceptability and perceptions of households was collected through questionnaires from 500 randomly selected households in the study districts. House index in three study districts reduced considerably during post-spray when compared to pre-spray. Kala-azar incidence in many districts was reduced after the DDT spray. Either partial or complete refusal was reported in 14.4%, while 35% were not satisfied with the suspension concentration and coverage; and 46.6% were found satisfied with the spraying procedure. Strengthening the IEC activities to sensitise the community, proper training of health personnel, monitoring of spray, good surveillance, proper treatment of cases and two rounds of DDT spray with good coverage in the endemic districts up to three years are essential to achieve the desired total elimination of kala-azar in Bihar state.

  18. Manufacturing real wages in Mexico

    Directory of Open Access Journals (Sweden)

    López V Antonia

    2006-01-01

    Full Text Available In this paper we analyse the recent evolution and determinants of real wages in Mexico?s manufacturing sector, using theories based on the assumption of imperfect competition both in the product and in the labour markets, especially wage-bargain theory, insider-outsider and mark-up models. We show evidence that the Mexican labour market does not behave as a traditional competitive market. The proposed explanation for this fact is that some workers benefit from advantages when compared with others, so that they can get a greater share of the proceedings of the productive process. Also, we find that changes in the degree of competition in the market for output influence the behaviour of real wages.

  19. History of nonnative Monk Parakeets in Mexico.

    Science.gov (United States)

    Hobson, Elizabeth A; Smith-Vidaurre, Grace; Salinas-Melgoza, Alejandro

    2017-01-01

    Nonnative Monk Parakeets have been reported in increasing numbers across many cities in Mexico, and were formally classified as an invasive species in Mexico in late 2016. However, there has not been a large-scale attempt to determine how international pet trade and national and international governmental regulations have played a part in colonization, and when the species appeared in different areas. We describe the changes in regulations that led the international pet trade market to shift to Mexico, then used international trade data to determine how many parakeets were commercially imported each year and where those individuals originated. We also quantified the recent increases in Monk Parakeet (Myiopsitta monachus) sightings in Mexico in both the scientific literature and in citizen science reports. We describe the timeline of increased reports to understand the history of nonnative Monk Parakeets in Mexico. As in other areas where the species has colonized, the main mode of transport is through the international pet trade. Over half a million Monk Parakeets were commercially imported to Mexico during 2000-2015, with the majority of importation (90%) occurring in 2008-2014, and almost all (98%) were imported from Uruguay. The earliest record of a free-flying Monk Parakeet was observed during 1994-1995 in Mexico City, but sightings of the parakeets did not become geographically widespread in either the scientific literature or citizen science databases until 2012-2015. By 2015, parakeets had been reported in 97 cities in Mexico. Mexico City has consistently seen steep increases in reporting since this species was first reported in Mexico. Here we find that both national and international legal regulations and health concerns drove a rise and fall in Monk Parakeet pet trade importations, shortly followed by widespread sightings of feral parakeets across Mexico. Further monitoring of introduced Monk Parakeet populations in Mexico is needed to understand the

  20. Significance of Hemispheric Security for Mexico

    Science.gov (United States)

    2003-04-07

    La Seguridad Internacional, la Nueva Geopolitica Continental y Mexico ,” Seminario Internacional sobre Misiones de Paz, Seguridad y Defensa, Rio de...USAWC STRATEGY RESEARCH PROJECT SIGNIFICANCE OF HEMISPHERIC SECURITY FOR MEXICO by LTC Enrique Garcia Jaramillo Cavalry, Mexican Army COL Joseph R...xx-xx-2002 to xx-xx-2003 4. TITLE AND SUBTITLE Significance of Hemispheric Security for Mexico Unclassified 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c

  1. Initiation devices, initiation systems including initiation devices and related methods

    Energy Technology Data Exchange (ETDEWEB)

    Daniels, Michael A.; Condit, Reston A.; Rasmussen, Nikki; Wallace, Ronald S.

    2018-04-10

    Initiation devices may include at least one substrate, an initiation element positioned on a first side of the at least one substrate, and a spark gap electrically coupled to the initiation element and positioned on a second side of the at least one substrate. Initiation devices may include a plurality of substrates where at least one substrate of the plurality of substrates is electrically connected to at least one adjacent substrate of the plurality of substrates with at least one via extending through the at least one substrate. Initiation systems may include such initiation devices. Methods of igniting energetic materials include passing a current through a spark gap formed on at least one substrate of the initiation device, passing the current through at least one via formed through the at least one substrate, and passing the current through an explosive bridge wire of the initiation device.

  2. Binational Teacher Development: Teacher Ambassador Exchange Program, New Mexico, USA and Nuevo Leon, Mexico.

    Science.gov (United States)

    Habermann, Mary Jean

    The report describes the rationale for and history of an exchange program for Nuevo Leon (Mexico) and New Mexico bilingual education teachers. The program evolved from the need to help Spanish-speaking students maintain their own language and culture while in the United States. New Mexico's state policy concerning language-minority children and…

  3. Elimination of Onchocerciasis from Mexico

    Science.gov (United States)

    Rodríguez-Pérez, Mario A.; Fernández-Santos, Nadia A.; Orozco-Algarra, María E.; Rodríguez-Atanacio, José A.; Domínguez-Vázquez, Alfredo; Rodríguez-Morales, Kristel B.; Real-Najarro, Olga; Prado-Velasco, Francisco G.; Cupp, Eddie W.; Richards, Frank O.; Hassan, Hassan K.; González-Roldán, Jesús F.; Kuri-Morales, Pablo A.; Unnasch, Thomas R.

    2015-01-01

    Background Mexico is one of the six countries formerly endemic for onchocerciasis in Latin America. Transmission has been interrupted in the three endemic foci of that country and mass drug distribution has ceased. Three years after mass drug distribution ended, post-treatment surveillance (PTS) surveys were undertaken which employed entomological indicators to check for transmission recrudescence. Methodology/Principal findings In-depth entomologic assessments were performed in 18 communities in the three endemic foci of Mexico. None of the 108,212 Simulium ochraceum s.l. collected from the three foci were found to contain parasite DNA when tested by polymerase chain reaction-enzyme-linked immunosorbent assay (PCR-ELISA), resulting in a maximum upper bound of the 95% confidence interval (95%-ULCI) of the infective rate in the vectors of 0.035/2,000 flies examined. This is an order of magnitude below the threshold of a 95%-ULCI of less than one infective fly per 2,000 flies tested, the current entomological criterion for interruption of transmission developed by the international community. The point estimate of seasonal transmission potential (STP) was zero, and the upper bound of the 95% confidence interval for the STP ranged from 1.2 to 1.7 L3/person/season in the different foci. This value is below all previous estimates for the minimum transmission potential required to maintain the parasite population. Conclusions/Significance The results from the in-depth entomological post treatment surveillance surveys strongly suggest that transmission has not resumed in the three foci of Mexico during the three years since the last distribution of ivermectin occurred; it was concluded that transmission remains undetectable without intervention, and Onchocerca volvulus has been eliminated from Mexico. PMID:26161558

  4. The outer Gulf of Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Henery, D. [Shell Internationale Petroleum Maatschappij BV, Den Haag (Netherlands)

    1996-12-31

    This paper deals with the offshore activity in the Gulf of Mexico. Up to the end of 1995 there have been close to 300 exploratory wells drilled in water depths beyond 450 metres, and over 50 development wells. In addition approximately 1.500 leases have been awarded in the deep water. Themes discussed are deep water discoveries, average well rates, and key learnings points

  5. Elimination of Onchocerciasis from Mexico.

    Directory of Open Access Journals (Sweden)

    Mario A Rodríguez-Pérez

    Full Text Available Mexico is one of the six countries formerly endemic for onchocerciasis in Latin America. Transmission has been interrupted in the three endemic foci of that country and mass drug distribution has ceased. Three years after mass drug distribution ended, post-treatment surveillance (PTS surveys were undertaken which employed entomological indicators to check for transmission recrudescence.In-depth entomologic assessments were performed in 18 communities in the three endemic foci of Mexico. None of the 108,212 Simulium ochraceum s.l. collected from the three foci were found to contain parasite DNA when tested by polymerase chain reaction-enzyme-linked immunosorbent assay (PCR-ELISA, resulting in a maximum upper bound of the 95% confidence interval (95%-ULCI of the infective rate in the vectors of 0.035/2,000 flies examined. This is an order of magnitude below the threshold of a 95%-ULCI of less than one infective fly per 2,000 flies tested, the current entomological criterion for interruption of transmission developed by the international community. The point estimate of seasonal transmission potential (STP was zero, and the upper bound of the 95% confidence interval for the STP ranged from 1.2 to 1.7 L3/person/season in the different foci. This value is below all previous estimates for the minimum transmission potential required to maintain the parasite population.The results from the in-depth entomological post treatment surveillance surveys strongly suggest that transmission has not resumed in the three foci of Mexico during the three years since the last distribution of ivermectin occurred; it was concluded that transmission remains undetectable without intervention, and Onchocerca volvulus has been eliminated from Mexico.

  6. Real, Regulated and Relative Poverty in the U.S.-Mexico Borderlands.

    Science.gov (United States)

    Stoddard, Ellwyn R.

    The essay explores the extent to which poverty exists among the residents of the U.S.-Mexico Borderlands. The sequence followed in this analysis is an initial clarification of some conceptual perspectives surrounding the problem followed by a survey of current economic conditions and growth potential for the Borderlands region. Following a brief…

  7. Gambling Trends in the State of New Mexico: 1996-1998

    Science.gov (United States)

    Blankenship, Jason; Starling, Randall; Woodall, W. G.; May, Philip A.

    2009-01-01

    New Mexico experienced a surge in the gaming industry during the mid-1990s with the initiation of a state lottery and other new gaming opportunities, as well as the development of many Indian gaming establishments. This paper explores patterns associated with gambling in two random samples of the adult population (N = 2674) in the entire State of…

  8. Modernizing Schools in Mexico: The Rise of Teacher Assessment and School-Based Management Policies

    Science.gov (United States)

    Echávarri, Jaime; Peraza, Cecilia

    2017-01-01

    In this paper we analyze the evolution of the teacher assessment policy and the origins of school-based management initiatives in the Mexican education context from the late 1980s until the last 2012-2013 Education Reform (RE2012-2013). Mexico joined the Global Education Reform Movement during the 1990s through the National Agreement for the…

  9. Early radioisotope uses in Mexico

    International Nuclear Information System (INIS)

    Segovia, N.; Tejera, A.; Bulbulian, S.; Palma, F.

    1991-10-01

    Mexico is traditionally a mining country and the first information about the presence of uranium is related to mine exploitation. Around 1945 when uranium became economically important, a rumor had spread that large amounts of black ceramics from Oaxaca were being purchased and sent abroad because of its assumed high uranium content. It was only in 1949 when minerals containing thorium and uranium were declared by law as 'National Reserves'. In those years a radium emanation plant was installed at the 'Hospital General' in Mexico City with the main purpose of carrying out radon seed implantation in tumors. In the fifties a radium dial painting facility was operating in the city of Toluca some 70 km from Mexico City. In 1955, when the National Commission of Nuclear Energy (CNEN) was founded by a government decree, two main activities were in sight: a training program on 'Radioisotope Techniques and Nuclear Instrumentation' and the creation of specialized laboratories. In this paper a general description of these events and undertakings spanning the decades 1940 to 1970 is given. (Author)

  10. Early radioisotope uses in Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Segovia, N; Tejera, A; Bulbulian, S; Palma, F

    1991-10-15

    Mexico is traditionally a mining country and the first information about the presence of uranium is related to mine exploitation. Around 1945 when uranium became economically important, a rumor had spread that large amounts of black ceramics from Oaxaca were being purchased and sent abroad because of its assumed high uranium content. It was only in 1949 when minerals containing thorium and uranium were declared by law as 'National Reserves'. In those years a radium emanation plant was installed at the 'Hospital General' in Mexico City with the main purpose of carrying out radon seed implantation in tumors. In the fifties a radium dial painting facility was operating in the city of Toluca some 70 km from Mexico City. In 1955, when the National Commission of Nuclear Energy (CNEN) was founded by a government decree, two main activities were in sight: a training program on 'Radioisotope Techniques and Nuclear Instrumentation' and the creation of specialized laboratories. In this paper a general description of these events and undertakings spanning the decades 1940 to 1970 is given. (Author)

  11. Yes… Mexico is a racist country

    DEFF Research Database (Denmark)

    Carrales, Juan Carlos Finck

    2017-01-01

    According to recent official statistics, in Mexico there is a relation between people’s privileges and their skin color: The lighter, the more privilege. However, social exclusion by racist practices in Mexico has been common practically since its Spanish conquest between 1519 and 1521, in which...... privileges where absorbed and monopolized by European settlers in Mexico (Spanish people: peninsulares) and their descendants (creole: criollos). As a consequence, currently in Mexico, the color of skin affects people’s economic and political privileges and powers in individual and social levels related...

  12. Country watch: Mexico.

    Science.gov (United States)

    Brito Lemus, A

    1996-01-01

    "LETRA S. SIDA. Cultura y Vida Cotidiana" is a monthly 16-page supplement that appears in the Mexican national newspaper "La Jornada." The supplement is produced by a nongovernmental organization (NGO) of the same name, and advertisements pay for the costs of production. Each issue studies a different AIDS theme, including women, indigenous people, migration, safe sex, homophobia, religion, and education. Each theme is approached from various perspectives, including epidemiology, medicine, sexuality, human rights, social science research, culture, and the arts. Populations most at risk are targeted. The aim is to arouse cultural criticism of taboos, prejudice and discrimination, sexual inequality, and gender issues that facilitate the transmission of HIV. Official health policies and the activities of groups, conservative and religious, which reject prevention programs are scrutinized. Each issue of the supplement includes a journalistic investigation providing statistics, facts, and opinions; interviews with health and education officials, politicians, state governors, and NGO staff; background articles by intellectuals, researchers, and well-known persons in Mexican society; PHA testimonies; reports on research and conferences; letters to the editor; cultural reviews relating to the theme of the issue; and a directory of NGOs doing HIV/AIDS work and of health institutions serving PHAs. The supplement has gone from a print run of 25,000 copies, when it was published as part of "El Nacional" (another government newspaper), to 70,000 in "La Jornada." The NGO has recently won the "Francisco Estrada Valle" award for its work.

  13. Sexual debut in Mexico: a comparison of household national surveys.

    Directory of Open Access Journals (Sweden)

    Cecilia Gayet

    2014-11-01

    Full Text Available Objective. To estimate calendar of sexual debut in Mexico and its trends using national representative household surveys. Materials and methods. Analysis of five birth cohorts extracted from four national population based household surveys in Mexico (National Health Survey 2000, National Survey on Demographic Dynamics 2009, National Youth Survey 2010, and National Health and Nutrition Survey 2012, using as outcome the proportion of individuals that reported sexual debut before the age of 16 and before the age of 20. Results. Overall, the four analyzed surveys produce consistent results, although some differences were found. While a larger proportion among younger cohorts reported sexual debut before the age of 20, that was not the case for sexual debut before 16 years. Conclusions. While data seems to reflect a relative stable age of sexual debut in Mexico, there is a recent trend to prepone sexual initiation that highlights the need to strengthen comprehensive sexual education and the supply of sexual and reproductive health services that are accessible and friendly to adolescents thus responding to the growing demand from this age group.

  14. Uranium solution mining: comparison of New Mexico with South Texas

    International Nuclear Information System (INIS)

    Conine, W.D.

    1980-01-01

    In-situ uranium-leaching or solution-mining operations are currently underway in both south Texas and Wyoming. Mobil Oil Corporation is in the process of applying solution-mining technology, such as that developed at the O'Hern facility in south Texas, to uranium orebodies located near Crownpoint, New Mexico. The O'Hern facility uses an alkaline-leach process to bring the uranium to the surface, where it is removed from solution using ion-exchange resin and chemical precipitation. Line-drive and five-spot well field patterns are used to inject and recover the leach solutions. Although details of ore occurrence in New Mexico differ from those in south Texas, laboratory, engineering-design, and field-hydrology tests indicate that solution mining of uranium should be feasible in New Mexico. To determine the commercial feasibility, Mobil is proceeding with the construction of pilot-plant facilities for a 75-gallon-perminute (gpm) test at an orebody near Crownpoint. The pilot test will use five-spot patterns at various spacings for production of uranium-bearing leachate. Initial surface processing will be the same as that used in south Texas

  15. The Enzyme Function Initiative.

    Science.gov (United States)

    Gerlt, John A; Allen, Karen N; Almo, Steven C; Armstrong, Richard N; Babbitt, Patricia C; Cronan, John E; Dunaway-Mariano, Debra; Imker, Heidi J; Jacobson, Matthew P; Minor, Wladek; Poulter, C Dale; Raushel, Frank M; Sali, Andrej; Shoichet, Brian K; Sweedler, Jonathan V

    2011-11-22

    The Enzyme Function Initiative (EFI) was recently established to address the challenge of assigning reliable functions to enzymes discovered in bacterial genome projects; in this Current Topic, we review the structure and operations of the EFI. The EFI includes the Superfamily/Genome, Protein, Structure, Computation, and Data/Dissemination Cores that provide the infrastructure for reliably predicting the in vitro functions of unknown enzymes. The initial targets for functional assignment are selected from five functionally diverse superfamilies (amidohydrolase, enolase, glutathione transferase, haloalkanoic acid dehalogenase, and isoprenoid synthase), with five superfamily specific Bridging Projects experimentally testing the predicted in vitro enzymatic activities. The EFI also includes the Microbiology Core that evaluates the in vivo context of in vitro enzymatic functions and confirms the functional predictions of the EFI. The deliverables of the EFI to the scientific community include (1) development of a large-scale, multidisciplinary sequence/structure-based strategy for functional assignment of unknown enzymes discovered in genome projects (target selection, protein production, structure determination, computation, experimental enzymology, microbiology, and structure-based annotation), (2) dissemination of the strategy to the community via publications, collaborations, workshops, and symposia, (3) computational and bioinformatic tools for using the strategy, (4) provision of experimental protocols and/or reagents for enzyme production and characterization, and (5) dissemination of data via the EFI's Website, http://enzymefunction.org. The realization of multidisciplinary strategies for functional assignment will begin to define the full metabolic diversity that exists in nature and will impact basic biochemical and evolutionary understanding, as well as a wide range of applications of central importance to industrial, medicinal, and pharmaceutical efforts.

  16. An Initiative for the Study and Use of Genetic Diversity of Domesticated Plants and Their Wild Relatives

    Science.gov (United States)

    Mastretta-Yanes, Alicia; Acevedo Gasman, Francisca; Burgeff, Caroline; Cano Ramírez, Margarita; Piñero, Daniel; Sarukhán, José

    2018-01-01

    Domestication has been influenced by formal plant breeding since the onset of intensive agriculture and the Green Revolution. Despite providing food security for some regions, intensive agriculture has had substantial detrimental consequences for the environment and does not fulfill smallholder’s needs under most developing countries conditions. Therefore, it is necessary to look for alternative plant production techniques, effective for each environmental, socio-cultural, and economic conditions. This is particularly relevant for countries that are megadiverse and major centers of plant domestication and diversification. In this white paper, a Mexico-centered initiative is proposed, with two main objectives: (1) to study, understand, conserve, and sustainably use the genetic diversity of domesticated plants and their wild relatives, as well as the ongoing evolutionary processes that generate and maintain it; and (2) to strengthen food and forestry production in a socially fair and environmentally friendly way. To fulfill these objectives, the initiative focuses on the source of variability available for domestication (genetic diversity and functional genomics), the context in which domestication acts (breeding and production) and one of its main challenges (environmental change). Research on these components can be framed to target and connect both the theoretical understanding of the evolutionary processes, the practical aspects of conservation, and food and forestry production. The target, main challenges, problems to be faced and key research questions are presented for each component, followed by a roadmap for the consolidation of this proposal as a national initiative. PMID:29515612

  17. An Initiative for the Study and Use of Genetic Diversity of Domesticated Plants and Their Wild Relatives

    Directory of Open Access Journals (Sweden)

    Alicia Mastretta-Yanes

    2018-02-01

    Full Text Available Domestication has been influenced by formal plant breeding since the onset of intensive agriculture and the Green Revolution. Despite providing food security for some regions, intensive agriculture has had substantial detrimental consequences for the environment and does not fulfill smallholder’s needs under most developing countries conditions. Therefore, it is necessary to look for alternative plant production techniques, effective for each environmental, socio-cultural, and economic conditions. This is particularly relevant for countries that are megadiverse and major centers of plant domestication and diversification. In this white paper, a Mexico-centered initiative is proposed, with two main objectives: (1 to study, understand, conserve, and sustainably use the genetic diversity of domesticated plants and their wild relatives, as well as the ongoing evolutionary processes that generate and maintain it; and (2 to strengthen food and forestry production in a socially fair and environmentally friendly way. To fulfill these objectives, the initiative focuses on the source of variability available for domestication (genetic diversity and functional genomics, the context in which domestication acts (breeding and production and one of its main challenges (environmental change. Research on these components can be framed to target and connect both the theoretical understanding of the evolutionary processes, the practical aspects of conservation, and food and forestry production. The target, main challenges, problems to be faced and key research questions are presented for each component, followed by a roadmap for the consolidation of this proposal as a national initiative.

  18. An Initiative for the Study and Use of Genetic Diversity of Domesticated Plants and Their Wild Relatives.

    Science.gov (United States)

    Mastretta-Yanes, Alicia; Acevedo Gasman, Francisca; Burgeff, Caroline; Cano Ramírez, Margarita; Piñero, Daniel; Sarukhán, José

    2018-01-01

    Domestication has been influenced by formal plant breeding since the onset of intensive agriculture and the Green Revolution. Despite providing food security for some regions, intensive agriculture has had substantial detrimental consequences for the environment and does not fulfill smallholder's needs under most developing countries conditions. Therefore, it is necessary to look for alternative plant production techniques, effective for each environmental, socio-cultural, and economic conditions. This is particularly relevant for countries that are megadiverse and major centers of plant domestication and diversification. In this white paper, a Mexico-centered initiative is proposed, with two main objectives: (1) to study, understand, conserve, and sustainably use the genetic diversity of domesticated plants and their wild relatives, as well as the ongoing evolutionary processes that generate and maintain it; and (2) to strengthen food and forestry production in a socially fair and environmentally friendly way. To fulfill these objectives, the initiative focuses on the source of variability available for domestication ( genetic diversity and functional genomics ), the context in which domestication acts ( breeding and production ) and one of its main challenges ( environmental change ). Research on these components can be framed to target and connect both the theoretical understanding of the evolutionary processes, the practical aspects of conservation, and food and forestry production. The target, main challenges, problems to be faced and key research questions are presented for each component, followed by a roadmap for the consolidation of this proposal as a national initiative.

  19. Targets and timelines for reducing salt in processed food in the Americas.

    Science.gov (United States)

    Campbell, Norm; Legowski, Barbara; Legetic, Branka; Ferrante, Daniel; Nilson, Eduardo; Campbell, Christine; L'Abbé, Mary

    2014-09-01

    Reducing dietary salt is one of the most effective interventions to lessen the burden of premature death and disability. In high-income countries and those in nutrition transition, processed foods are a significant if not the main source of dietary salt. Reformulating these products to reduce their salt content is recommended as a best buy to prevent chronic diseases across populations. In the Americas, there are targets and timelines for reduced salt content of processed foods in 8 countries--Argentina, Brazil, Canada, Chile, Ecuador, Mexico, and the National Salt Reduction Initiative in the United States and Paraguay. While there are common elements across the countries, there are notable differences in their approaches: 4 countries have exclusively voluntary targets, 2 countries have combined voluntary and regulated components, and 1 country has only regulations. The countries have set different types of targets and in some cases combined them: averages, sales-weighted averages, upper limits, and percentage reductions. The foods to which the targets apply vary from single categories to comprehensive categories accounting for all processed products. The most accessible and transparent targets are upper limits per food category. Most likely to have a substantive and sustained impact on salt intake across whole populations is the combination of sales-weighted averages and upper limits. To assist all countries with policies to improve the overall nutritional value of processed foods, the authors call for food companies to supply food composition data and product sales volume data to transparent and open-access platforms and for global companies to supply the products that meet the strictest targets to all markets. Countries participating in common markets at the subregional level can consider harmonizing targets, nutrition labels, and warning labels. ©2014 Wiley Periodicals, Inc.

  20. Deportation and mental health among migrants who inject drugs along the US-Mexico border

    Science.gov (United States)

    Pinedo, Miguel; Burgos, José Luis; Zúñiga, María Luisa; Perez, Ramona; Macera, Caroline A.; Ojeda, Victoria D.

    2016-01-01

    Objective This study describes the prevalence and factors of depressive symptoms among a sample of persons who inject drugs (PWID) with a history of deportation from the US in Tijuana, Mexico. In 2014, 132 deported PWID completed a structured questionnaire. Depressive symptoms were measured using the Center for Epidemiologic Studies Short Depression Scale (CESD-10) screening instrument. Eligible participants were ≥18 years old, injected drugs in the past month, spoke English or Spanish, and resided in Tijuana. Multivariate analyses identified factors associated with depressive symptoms. Among deported PWID, 45% reported current symptoms of depression. Deported PWID who were initially detained in the US for a crime-related reason before being deported (Adjusted Odds Ratio (AOR): 5.27; 95% CI: 1.79–15.52) and who perceived needing help with their drug use (AOR: 2.15; 95% 1.01–4.61) had higher odds of reporting depressive symptoms. Our findings highlight the need for effective strategies targeting deported migrants who inject drugs to treat mental health and drug abuse in Tijuana. Investing in the mental health of deported PWID may also be a viable HIV prevention strategy. PMID:27132880

  1. Vibrio cholerae Classical Biotype Strains Reveal Distinct Signatures in Mexico

    OpenAIRE

    Alam, Munirul; Islam, M. Tarequl; Rashed, Shah Manzur; Johura, Fatema-tuz; Bhuiyan, Nurul A.; Delgado, Gabriela; Morales, Rosario; Mendez, Jose Luis; Navarro, Armando; Watanabe, Haruo; Hasan, Nur-A; Colwell, Rita R.; Cravioto, Alejandro

    2012-01-01

    Vibrio cholerae O1 classical (CL) biotype caused the fifth and sixth pandemics, and probably the earlier cholera pandemics, before the El Tor (ET) biotype initiated the seventh pandemic in Asia in the 1970s by completely displacing the CL biotype. Although the CL biotype was thought to be extinct in Asia and although it had never been reported from Latin America, V. cholerae CL and ET biotypes, including a hybrid ET, were found associated with areas of cholera endemicity in Mexico between 199...

  2. Guidebook to Rio Grande rift in New Mexico

    Science.gov (United States)

    Hawley, J.W.

    1978-01-01

    Discusses the details of geologic features along the rift zone. Included are short papers on topics relative to the overall region. These papers and the road logs are of special interest to any one pursuing further study of the rift. This book is a comprehensive guide to the middle and late Cenozoic geology of the Rio Grande region of Colorado and New Mexico. Though initially used on field trips for the International Symposium on Tectonics and Magmatism of the Rio Grande rift, the guidebook will be useful to anyone interested in the Cenozoic history of the 600-mi-long area extending from central Colorado to El Paso, Texas.

  3. Combat Wound Initiative program.

    Science.gov (United States)

    Stojadinovic, Alexander; Elster, Eric; Potter, Benjamin K; Davis, Thomas A; Tadaki, Doug K; Brown, Trevor S; Ahlers, Stephen; Attinger, Christopher E; Andersen, Romney C; Burris, David; Centeno, Jose; Champion, Hunter; Crumbley, David R; Denobile, John; Duga, Michael; Dunne, James R; Eberhardt, John; Ennis, William J; Forsberg, Jonathan A; Hawksworth, Jason; Helling, Thomas S; Lazarus, Gerald S; Milner, Stephen M; Mullick, Florabel G; Owner, Christopher R; Pasquina, Paul F; Patel, Chirag R; Peoples, George E; Nissan, Aviram; Ring, Michael; Sandberg, Glenn D; Schaden, Wolfgang; Schultz, Gregory S; Scofield, Tom; Shawen, Scott B; Sheppard, Forest R; Stannard, James P; Weina, Peter J; Zenilman, Jonathan M

    2010-07-01

    The Combat Wound Initiative (CWI) program is a collaborative, multidisciplinary, and interservice public-private partnership that provides personalized, state-of-the-art, and complex wound care via targeted clinical and translational research. The CWI uses a bench-to-bedside approach to translational research, including the rapid development of a human extracorporeal shock wave therapy (ESWT) study in complex wounds after establishing the potential efficacy, biologic mechanisms, and safety of this treatment modality in a murine model. Additional clinical trials include the prospective use of clinical data, serum and wound biomarkers, and wound gene expression profiles to predict wound healing/failure and additional clinical patient outcomes following combat-related trauma. These clinical research data are analyzed using machine-based learning algorithms to develop predictive treatment models to guide clinical decision-making. Future CWI directions include additional clinical trials and study centers and the refinement and deployment of our genetically driven, personalized medicine initiative to provide patient-specific care across multiple medical disciplines, with an emphasis on combat casualty care.

  4. Energy Technologies Research and Education Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Ghassemi, Abbas [New Mexico State Univ., Las Cruces, NM (United States); Ranade, Satish [New Mexico State Univ., Las Cruces, NM (United States)

    2014-12-31

    For this project, the intended goal of the microgrid component was to investigate issues in policy and technology that would drive higher penetration of renewable energy, and to demonstrate implementation in a utility system. The work accomplished on modeling the dynamics of photovoltaic (PV) penetration can be expanded for practical application. Using such a tool those involved in public policy can examine what the effect of a particular policy initiative, e.g., renewable portfolio standards (RPS) requirements, might be in terms of the desired targets. The work in the area of microgrid design, protection, and operation is fundamental to the development of microgrids. In particular the “Energy Delivery” paradigm provides new opportunities and business models for utilities. Ultimately, Energy Delivery could accrue significant benefits in terms of costs and resiliency. The experimental microgrid will support continued research and allow the demonstration of technology for better integration of renewables. The algal biofuels component of the project was developed to enhance the test facility and to investigate the technical and economic feasibility of a commercial-scale geothermal algal biofuels operation for replication elsewhere in the arid Southwest. The project was housed at New Mexico State University’s (NMSU’s) Geothermal Aquaculture Facility (GAF) and a design for the inoculation train and algae grow-out process was developed. The facility was upgraded with modifications to existing electrical, plumbing and structural components on the GAF and surrounding grounds. The research work was conducted on biomass-processing, harvesting, dewatering, and extraction. Additionally, research was conducted to determine viability of using low-cost, wastewater from municipal treatment plants in the cultivation units as make-up water and as a source of nutrients, including nitrogen and soluble phosphorus. Data was collected on inputs and outputs, growth evaluation and

  5. Initial response of a rock penetrator

    International Nuclear Information System (INIS)

    Longcope, D.B.; Grady, D.E.

    1977-12-01

    An analysis based on elastic rod theory is given for the early-time axisymmetric response of pointed penetrators. Results of measurements by laser interferometry of the back surface particle velocity of laboratory scale penetrators impacted by sandstone targets are presented. Values of the initial pressure on the penetrator tip are determined which give good agreement between the analytical and experimental results. These initial tip pressures are found to be approximated by the stress-particle velocity Hugoniot for the target material

  6. On some birds from southern Mexico

    NARCIS (Netherlands)

    Mees, G.F.

    1970-01-01

    In the years 1962/64 our museum purchased from Mr. Otto Epping, now of Pittsburgh, U.S.A., a collection of 700 bird-specimens from southern Mexico (mainly from Vera Cruz and Oaxaca, a few specimens from Puebla). As our museum was poorly provided with material from Mexico, this was a very welcome

  7. Facing NAFTA: Literacy and Work in Mexico.

    Science.gov (United States)

    Flores, Gloria Hernandez; Lankshear, Colin

    2000-01-01

    Outlines the deep and complex challenge faced by Mexico in its quest for closer economic integration with so-called advanced economies. Discusses extensive poverty and illiteracy, and the systematic exclusion of many people from access to the very kinds of learning required by Mexico's economic project. Argues that extraordinary efforts and…

  8. Interdisciplinary Education and Research in Mexico

    Science.gov (United States)

    Villa-Soto, Juan Carlos

    2016-01-01

    In this article we discuss interdisciplinary teaching and research in Latin America through the lens of Mexican perspectives, in particular the experiences at the National Autonomous University of Mexico (UNAM). The history of these experiences goes back to the creation of the frst interdisciplinary education programs in Mexico in the 1970s and…

  9. LCA of road infrastructure in Mexico City.

    NARCIS (Netherlands)

    Rosales Carreon, Jesus

    2007-01-01

    Vehicular traffic is a major problem in metropolitan areas and Mexico City is no exception. Located in a pollutant-trapping valley, Mexico City (one of the largest cities in the world) is famous for its size, its history, and the warmth of its people. Nev

  10. Plutonium in the Gulf of Mexico

    International Nuclear Information System (INIS)

    Scott, M.R.; Salter, P.F.

    The geochemistry of fallout plutonium in the sediments of the Gulf of Mexico was studied. A series of sediment cores was collected in a traverse from the deep Gulf of Mexico to the Mississippi Delta. The cores were sliced into 1 cm intervals and analyzed for plutonium. Explanations for the variations in concentration are presented

  11. New Mexico English Remediation Taskforce Report

    Science.gov (United States)

    New Mexico Higher Education Department, 2016

    2016-01-01

    In March, 2016, the state of New Mexico established a Remediation Task Force to examine remediation reform efforts across the state's higher education institutions. On March 11, the Task Force met for the "New Mexico Corequisite Remediation at Scale Policy Institute" in order to learn about the results of the latest national reform…

  12. 50 CFR 32.50 - New Mexico.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false New Mexico. 32.50 Section 32.50 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) THE... § 32.50 New Mexico. The following refuge units have been opened for hunting and/or fishing, and are...

  13. 40 CFR 81.332 - New Mexico.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false New Mexico. 81.332 Section 81.332... AREAS FOR AIR QUALITY PLANNING PURPOSES Section 107 Attainment Status Designations § 81.332 New Mexico. New Mexico—TSP Designated area Does not meet primary standards Does not meet secondary standards...

  14. 40 CFR 81.421 - New Mexico.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false New Mexico. 81.421 Section 81.421 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF... Visibility Is an Important Value § 81.421 New Mexico. Area name Acreage Public Law establishing Federal land...

  15. New Mexico Known Mineral Deposit Areas

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains all Known Mineral Deposit Areas in the state of New Mexico. It is in a vector digital structure digitized from a 1:500,000 scale map of the...

  16. Postgraduate Professional Pedagogical Education in Mexico

    Science.gov (United States)

    Zhyzhko, Olena

    2015-01-01

    This article is the result of scientific comparative-pedagogical research, which purpose was to highlight the main features of postgraduate professional pedagogical education in Mexico. The author found that the postgraduate professional pedagogical education in Mexico is performed by public and private higher education institutions: higher…

  17. Eco-bio-social determinants for house infestation by non-domiciliated Triatoma dimidiata in the Yucatan Peninsula, Mexico.

    Directory of Open Access Journals (Sweden)

    Eric Dumonteil

    Full Text Available BACKGROUND: Chagas disease is a vector-borne disease of major importance in the Americas. Disease prevention is mostly limited to vector control. Integrated interventions targeting ecological, biological and social determinants of vector-borne diseases are increasingly used for improved control. METHODOLOGY/PRINCIPAL FINDINGS: We investigated key factors associated with transient house infestation by T. dimidiata in rural villages in Yucatan, Mexico, using a mixed modeling approach based on initial null-hypothesis testing followed by multimodel inference and averaging on data from 308 houses from three villages. We found that the presence of dogs, chickens and potential refuges, such as rock piles, in the peridomicile as well as the proximity of houses to vegetation at the periphery of the village and to public light sources are major risk factors for infestation. These factors explain most of the intra-village variations in infestation. CONCLUSIONS/SIGNIFICANCE: These results underline a process of infestation distinct from that of domiciliated triatomines and may be used for risk stratification of houses for both vector surveillance and control. Combined integrated vector interventions, informed by an Ecohealth perspective, should aim at targeting several of these factors to effectively reduce infestation and provide sustainable vector control.

  18. Technological Middle Level Education in Mexico

    Directory of Open Access Journals (Sweden)

    Silvia Cruz Prieto

    2014-02-01

    Full Text Available Technological middle level education in Mexico trains young people between 15 to 18 years old to continue higher studies or to enter the labor market. It serves about 807,433 students through its 755 campuses with an educational model that has a focus on developing competences. High School Educational Reform, in operation since 2008, has initiated some programs to serve students, with the aim of reducing dropout rates. It also has implemented innovative management and information systems. In 2013, an educational reform was begun with an orientation to working conditions, focusing on the evaluation of school administrators and teachers. Received: 25/09/2013 / Accepted: 03/10/2013How to reference this articleCruz Prieto, S., Egido, I. (2014. La Educación Tecnológica de Nivel Medio Superior en México. Foro de Educación, 12(16, pp. 99-121. doi: http://dx.doi.org/10.14516/fde.2014.012.016.004

  19. Saving and credit cooperatives in Mexico

    Directory of Open Access Journals (Sweden)

    Martha E. Izquierdo Muciño

    2015-11-01

    Full Text Available The Saving service and Credit Popular (Cajas de Ahorro y Credito Popular first appeared in Mexico in 1951 at the initiative of the priest Pedro Velazquez, similar to the popular savings banks that existed in Canada, which had been founded by Alphonse Desjardins in the early XX century.These savings service (Cajas de Ahorro were developing successfully in almost all Mexican communities, most of them remained faithful to the principles and ordinances of the church that gave rise to them, without the government participate in this activity and without policies encouraging or regulatory actions. It was not until 1991 when the General Law of Organizations and Auxiliary Credit Activities (Ley General de Organizaciones y Actividades was enacted. However in 2000 they began to emerge problems arising from fraudulent activities by some people taking advantage of loopholes established irregular saving services. Consequently and in order to solve these problems was changing the law. The last of the fraud occurred with the popular financial called FICREA (2015, to which was amended regulatory law again and while thus sought to avoid another fraud, who really was affected is a large amount very poor indigenous and peasants.Received: 03.06.2015Accepted: 17.07.2015

  20. Inertial confinement fusion target

    International Nuclear Information System (INIS)

    Bourdier, A.

    2001-12-01

    A simple, zero-dimensional model describing the temporal behaviour of an imploding-shell, magnetized fuel inertial confinement fusion target is formulated. The addition of a magnetic field to the fuel reduces thermal conduction losses. As a consequence, it might lead to high gains and reduce the driver requirements. This beneficial effect of the magnetic field on thermonuclear gains is confirmed qualitatively by the zero-dimensional model results. Still, the extent of the initial-condition space for which significant gains can occur is not, by far, as large as previously reported. One-dimensional CEA code simulations which confirm this results are also presented. Finally, we suggest to study the approach proposed by Hasegawa. In this scheme, the laser target is not imploded, and the life-time of the plasma can be very much increased. (author)

  1. Advisable alternative fuels for Mexico; Combustibles alternativos convenientes para Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Aguilar Gonzalez, Jorge Luis [ICA Fluor (Mexico)

    2007-07-15

    The alternative fuels are born with the goal of not damaging the environment; biodiesel, electricity, ethanol, hydrogen, methanol, natural gas, LP gas, are the main alternative fuels. However, the biodiesel and bioetanol are the only completely renewable ones, this makes them ideal to be developed in Mexico, since the agricultural sector could be fortified, the technological independence be favored, improve the conservation of the oil resources and by all means not to affect the environment. On the other hand, also efficient cultivation techniques should be developed to guarantee the economy of the process. [Spanish] Los combustibles alternativos nacen con la meta de no danar el medio ambiente; el biodiesel, electricidad, etanol, hidrogeno, metanol, gas natural, gas LP, son los principales combustibles alternativos. No obstante, el biodiesel y el bioetanol son los unicos completamente renovables, esto los hace ideales para desarrollarse en Mexico, ya que se podria fortalecer el sector agricola, favorecer la independencia tecnologica, mejorar la administracion de los recursos petroleros y por supuesto no afectar al medio ambiente. Por otro lado tambien se tendrian que desarrollar tecnicas de cultivo eficientes para garantizar la economia del proceso.

  2. Update of Geothermics in Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Gutierrez Negrin, Luis C.A.; Quijano Leon, Jose Luis [Comision Federal de Electricidad, Morelia, Michoacan (Mexico)

    2004-12-01

    Four geothermal fields are currently operating in Mexico (Cerro Prieto, Los Azufres, Los Humeros and Las Tres Virgenes), with a total installed geothermal-electric capacity of 953 megawatts (MW). This means the country is located in third place, worldwide, just behind the USA and Philippines. Thirty-six power plants of several types (condensing, back pressure and binary cycle), between 1.5 and 110 MW, operate in the fields, fed by 197 wells with a combined production of 7,700 metric tons of steam per hour (t/h). These production wells have depths between 600 and 4,400 meters. Steam comes with 8,750 t/h of brine that is injected through 19 injection wells or treated in a solar evaporation pond of 14 km2 in Cerro Prieto. During 2003, steam produced in those fields equaled 67.5 million metric tons, and the power plants generated 6,282 gigawatt-hours (GWh), which represented 3.1% of the electric energy produced in Mexico. All the power plants and the geothermal fields are operated bye the public utility, the Comision Federal de Electricidad (Comision Federal de Electricidad (CFE)). [Spanish] Actualmente se operan en Mexico cuatro campos geotermicos (Cerro Prieto, Los Azufres, Los Humeros y Las Tres Virgenes), con una capacidad geotermoelectrica total de 953 megawatts (MW). Esto coloca al pais en el tercer lugar mundial, detras de Estados Unidos y Filipinas. En esos campos operan treinta y seis unidades de tipos diversos (a condensacion, a contrapresion y de ciclo binario), entre 1.5 y 110 MW, alimentadas por 197 pozos con una produccion combinada de 7,700 toneladas de vapor por hora (t/h). Estos pozos productores tienen profundidades entre 600 y 4,400 metros. El vapor sale acompanado por 8,750 t/h de salmuera, que se inyecta en 19 pozos inyectores o se trata en una laguna de evaporacion solar de 14 km2 en Cerro Prieto. Durante 2003 el vapor producido en los campos sumo 67.5 millones de toneladas y las unidades generaron 6,282 gigawatts-hora (GWh), lo que represento el

  3. SANDIA MOUNTAIN WILDERNESS, NEW MEXICO.

    Science.gov (United States)

    Hedlund, D.C.; Kness, R.F.

    1984-01-01

    Geologic and mineral-resource investigations in the Sandia Mountains in New Mexico indicate that a small part of the area has a probable mineral-resource potential. Most of the mineral occurrences are small barite-fluorite veins that occur along faults on the eastern slope of the range. The barite veins in the Landsend area and in the Tunnel Spring area are classed as having a probable mineral-resource potential. Fluorite veins which occur at the La Luz mine contain silver-bearing galeana and the area near this mine is regarded as having a probable resource potential for silver. No energy resources were identified in this study.

  4. Toward better access to health insurance coverage for U.S. retirees in Mexico.

    Science.gov (United States)

    Warner, D C; Jahnke, L R

    2001-01-01

    Many retirees from the United States of America have limited health insurance coverage while living in Mexico. Medicare and Medicaid benefits are not portable to other countries and Medigap (private insurance that supplements Medicare) is very limited. This causes economic and medical hardships and serves as a barrier to retirement to Mexico. Increasing numbers of U.S. retirees will be interested in moving to Mexico in the future because of the climate, the culture, and the lower cost of living. The numbers are increasing as a result of several factors such as aging "baby boomers" and the rapidly growing Mexican-origin population in the U.S.A. who are citizens or permanent residents but would like to return to their communities of origin after working in the U.S.A. There are several policy initiatives that could provide opportunities for improving health insurance coverage for these retirees that could be cost-effective.

  5. 9 CFR 93.325 - Horses from Mexico.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Horses from Mexico. 93.325 Section 93... CONVEYANCE AND SHIPPING CONTAINERS Horses Mexico 18 § 93.325 Horses from Mexico. Horses offered for entry from Mexico shall be inspected as provided in §§ 93.306 and 93.323; shall be accompanied by a...

  6. Lidar Monitoring of Mexico City's Atmosphere During High Air Pollution Episodes

    Science.gov (United States)

    Quick, C. R., Jr.; Archuleta, F. L.; Hof, D. E.; Karl, R. R., Jr.; Tiee, J. J., Jr.; Eichinger, W. E.; Holtkamp, D. B.; Tellier, L.

    1992-01-01

    Over the last two decades, Mexico City, like many large industrial and populous urban areas, has developed a serious air pollution problem, especially during the winter months when there are frequent temperature inversions and weak winds. The deteriorating air quality is the result of several factors. The basin within which Mexico City lies in Mexico's center of political, administrative and economic activity, generating 34 percent of the gross domestic product and 42 percent of the industrial revenue, and supporting a population which is rapidly approaching the 20 million mark. The basin is surrounded by mountains on three sides which end up preventing rapid dispersal of pollutants. Emissions from the transportation fleet (more than 3 million vehicles) are one of the primary pollution sources, and most are uncontrolled. Catalytic converters are just now working their way into the fleet. The Mexico City Air Quality Research Initiative in an international collaboration project between the Los Alamos National Laboratory and the Mexican Petroleum Institute are dedicated to the investigation of the air quality problem in Mexico City. The main objective of the project is to identify and assess the cost and benefits of major options being proposed to improve the air quality. The project is organized into three main activity areas: (1) modeling and simulation; (2) characterization and measurements; and (3) strategic evaluation.

  7. The wind power of Mexico

    International Nuclear Information System (INIS)

    Hernandez-Escobedo, Q.; Manzano-Agugliaro, F.; Zapata-Sierra, A.

    2010-01-01

    The high price of fossil fuels and the environmental damage they cause have encouraged the development of renewable energy resources, especially wind power. This work discusses the potential of wind power in Mexico, using data collected every 10 min between 2000 and 2008 at 133 automatic weather stations around the country. The wind speed, the number of hours of wind useful for generating electricity and the potential electrical power that could be generated were estimated for each year via the modelling of a wind turbine employing a logistic curve. A linear correlation of 90.3% was seen between the mean annual wind speed and the mean annual number of hours of useful wind. Maps were constructed of the country showing mean annual wind speeds, useful hours of wind, and the electrical power that could be generated. The results show that Mexico has great wind power potential with practically the entire country enjoying more than 1700 h of useful wind per year and the potential to generate over 2000 kW of electrical power per year per wind turbine installed (except for the Chiapas's State). Indeed, with the exception of six states, over 5000 kW per year could be generated by each turbine. (author)

  8. Multiagency Initiative to Provide Greenhouse Gas Information

    Science.gov (United States)

    Boland, Stacey W.; Duren, Riley M.

    2009-11-01

    Global Greenhouse Gas Information System Workshop; Albuquerque, New Mexico, 20-22 May 2009; The second Greenhouse Gas Information System (GHGIS) workshop brought together 74 representatives from 28 organizations including U.S. government agencies, national laboratories, and members of the academic community to address issues related to the understanding, operational monitoring, and tracking of greenhouse gas emissions and carbon offsets. The workshop was held at Sandia National Laboratories and organized by an interagency collaboration among NASA centers, Department of Energy laboratories, and the U.S. National Oceanic and Atmospheric Administration. It was motivated by the perceived need for an integrated interagency, community-wide initiative to provide information about greenhouse gas sources and sinks at policy-relevant temporal and spatial scales. Such an initiative could significantly enhance the ability of national and regional governments, industry, and private citizens to implement and evaluate effective climate change mitigation policies.

  9. 78 FR 14983 - Fisheries of the Gulf of Mexico; Gulf of Mexico Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-03-08

    ... the Gulf of Mexico; Gulf of Mexico Fishery Management Council; Public Meeting AGENCY: National Marine... of Gulf of Mexico Fishery Management Council Spanish Mackerel and Cobia Stock Assessment Review Workshop. SUMMARY: Independent peer review of Gulf of Mexico Spanish Mackerel and Cobia stocks will be...

  10. 77 FR 56168 - Reef Fish Fishery of the Gulf of Mexico; Gulf of Mexico Individual Fishing Quota Programs

    Science.gov (United States)

    2012-09-12

    .... 090206140-91081-03] RIN 0648-XC227 Reef Fish Fishery of the Gulf of Mexico; Gulf of Mexico Individual... red snapper and grouper/tilefish components of the reef fish fishery in the Gulf of Mexico (Gulf), the... INFORMATION: The reef fish fishery of the Gulf of Mexico is managed under the Fishery Management Plan for Reef...

  11. Motivation Factors for Female Entrepreneurship in Mexico

    Directory of Open Access Journals (Sweden)

    Martha Cantú Cavada

    2017-09-01

    Full Text Available Objective: The objective of this paper is to analyse motivation factors for female entrepreneurship in Mexico. In the proposed article, the authors discuss the factors which compelled women to start their enterprises in Mexico. Research Design & Methods: Based on in-depth interviews with female entrepreneurs and entrepreneurship experts, the authors show which factors motivated women to start their own business in Mexico. Findings: The study proves that women in Mexico are motivated by a combination of push and pull factors, where the majority of the factors are pull factors. The findings of the study help to conclude that female entrepreneurship development is influenced by different factors including the entrepreneurs’ personal traits, social and economic factors. Due to their conservative traditional attitude, risk adverse tendency, and non-cooperation of family members, etc. women entrepreneurs are sometimes deterred to start a business in Mexico. Implications & Recommendations: It is necessary to raise the awareness of different factors that promote female entrepreneurship in Mexico. Governmental programmes which support female entrepreneurship, business incubators, and networking could be very helpful for women when starting their own business. Contribution & Value Added: The originality of this work lies in studying motivational factors for female entrepreneurship in Mexico. The Mexican society faces a big revolution towards female entrepreneurship. Based on the change of family structure and traditions, women nowadays are having more opportunities to develop as entrepreneurs.

  12. The environmental policy in Mexico: Crisis and perspectives; La politica ambiental en Mexico: Crisis y perspectivas

    Energy Technology Data Exchange (ETDEWEB)

    Urquidi, Victor [Colegio de Mexico, Mexico, D. F. (Mexico)

    1996-12-31

    In this paper some aspects of the environmental situation in Mexico are condensed. The main roll performed by the modality of the energy resources consumption and the evolution of the environmental policy in Mexico from 1971 to 1996 is analyzed. It is concluded that in Mexico it has not been able to define the environmental policy in all its extension requiring, therefore, a greater participation of all the sectors to protect Nature and fight against the industrial and municipal pollution [Espanol] En esta ponencia se resumen algunos aspectos de la situacion ambiental actual de Mexico. Se analiza el papel central desempenado por la modalidad del consumo de energeticos y la evolucion de la politica ambiental en Mexico desde 1971 hasta 1996. Se concluye en que la politica ambiental en Mexico no se ha podido definir todavia en todos sus alcances por lo que se requiere una mayor participacion de todos los sectores para proteger la naturaleza y combatir la contaminacion industrial y municipal

  13. The environmental policy in Mexico: Crisis and perspectives; La politica ambiental en Mexico: Crisis y perspectivas

    Energy Technology Data Exchange (ETDEWEB)

    Urquidi, Victor [Colegio de Mexico, Mexico, D. F. (Mexico)

    1997-12-31

    In this paper some aspects of the environmental situation in Mexico are condensed. The main roll performed by the modality of the energy resources consumption and the evolution of the environmental policy in Mexico from 1971 to 1996 is analyzed. It is concluded that in Mexico it has not been able to define the environmental policy in all its extension requiring, therefore, a greater participation of all the sectors to protect Nature and fight against the industrial and municipal pollution [Espanol] En esta ponencia se resumen algunos aspectos de la situacion ambiental actual de Mexico. Se analiza el papel central desempenado por la modalidad del consumo de energeticos y la evolucion de la politica ambiental en Mexico desde 1971 hasta 1996. Se concluye en que la politica ambiental en Mexico no se ha podido definir todavia en todos sus alcances por lo que se requiere una mayor participacion de todos los sectores para proteger la naturaleza y combatir la contaminacion industrial y municipal

  14. First report of myxomatosis in Mexico.

    Science.gov (United States)

    Licón Luna, R M

    2000-07-01

    An outbreak of myxomatosis occurred between September and October 1993 on a rabbit farm in Punta Colnett (Ensenada, Baja California in northwestern Mexico, Transpeninsular Highway, km 128) and was confirmed by the Mexico-USA Commission for Prevention of Foreign Diseases of Animals (CPA). This represents the first officially confirmed case of the disease in Mexico. Like the cases in California (USA), the brush rabbit (Sylvilagus bachmani) seems to be the carrier of the virus, since serum samples from wild rabbits from different areas of the peninsula of Baja California were found to contain antibodies against the myxoma virus.

  15. NAFTA and Mexico's Tax Policy Reform

    OpenAIRE

    Jorge Martinez-Vazquez; Duanje Chen

    2001-01-01

    The North American Free Trade Agreement (NAFTA) has had a significant effect on Mexico’s economy and institutions. The ongoing consideration of tax reform in Mexico requires an evaluation of the role of NAFTA in Mexico’s economy, including its tax structure; it also requires an assessment of the impact of the Mexico’s tax system on the trade and capital flows between Mexico and its NAFTA partners, the United States and Canada. Clearly, no good tax reform in Mexico can ignore the role of NAFTA...

  16. The economic impact of Sandia National Laboratories on Central New Mexico and the State of New Mexico Fiscal Year 1998; ANNUAL

    International Nuclear Information System (INIS)

    Lansford, Robert R.; Adcock, Larry D.; Gentry, Lucille M.; Ben-David, Shaul; Temple, John

    1999-01-01

    Sandia National Laboratories (SNL) is a Department of Energy federally funded national security laboratory that uses engineering and science to ensure the security of the Nation. SNL provides scientific and engineering solutions to meet national needs in nuclear weapons and related defense systems, energy security, and environmental integrity. SNL works in partnerships with universities and industry to enhance their mission and transfer technology that will address emerging national challenges for both government and industry. For several years, the U.S. Department of Energy (DOE) Albuquerque Operations Office (AL) and New Mexico State University (NMSU) have maintained an inter-industry, input-output (I/O) model with capabilities to assess the impacts of developments initiated outside the economy such as federal DOE monies that flow into the state, on an economy. This model will be used to assess economic, personal income and employment impacts of SNL on Central New Mexico and the State of New Mexico. Caution should be exercised when comparing economic impacts between fiscal years prior to this report. The I/O model was rebased for FY 1998. The fringe benefits coefficients have been updated for the FY 1996 and FY 1997 economic impacts analysis. Prior to FY 1993 two different I/O base models were used to estimate the impacts. New technical information was released by the Bureau of Economic Analysis (BEA), U.S. Department of Commerce in 1991 and in 1994 and was incorporated in FY 1991, FY 1993, and FY 1994 I/O models. Also in 1993, the state and local tax coefficients and expenditure patterns were updated from a 1986 study for the FY 1992 report. Further details about the input-output model can be found in ''The Economic Impact of the Department of Energy on the State of New Mexico-FY 1998'' report by Lansford, et al. (1999). For this report, the reference period is FY 1998 (October 1, 1997, through September 30, 1998) and includes two major impact analyses: The

  17. AECL's new environmental initiatives

    International Nuclear Information System (INIS)

    McDonnell, F.N.

    1993-01-01

    AECL's research and development expenditures in environmental sciences and waste management technology are about $50 M per year. The main focus of these programs is the Nuclear Fuel Waste Management Program. This research is supplemented by activities in support of laboratory, Environmental Authority and internal waste management requirements, as well as provision of non-nuclear services. AECL intends to become more involved in performing environmental research and development with broader application. The goal is to achieve a relationship with Canadian industry that would involve a substantial portion of AECL's environmental research capabilities. The research directions and priorities of the resulting partnership would be set by the private sector in accordance with their needs and requirements. It is expected that the activities associated with this new environmental initiative will start small and grow in response to perceived needs. AECL is now increasing its non-nuclear research efforts by targeting those markets that appear most attractive. The thrust can be divided into three broad categories: environmental research, environmental services, and environmental products. (Author)

  18. The Man Who Tamed Mexico's Tiger: General Joaquin Amaro and the Professionalization of Mexico's Revolutionary Army

    National Research Council Canada - National Science Library

    Carriedo, Robert

    2005-01-01

    .... While effective in overthrowing Diaz, Mexico's revolutionary armies neither disbanded nor submitted themselves to civilian rule, but instead retained their character as undisciplined and fiercely...

  19. Anisotropic models to account for large borehole washouts to estimate gas hydrate saturations in the Gulf of Mexico Gas Hydrate Joint Industry Project Leg II Alaminos 21 B well

    Science.gov (United States)

    Lee, M.W.; Collett, T.S.; Lewis, K.A.

    2012-01-01

    Through the use of 3-D seismic amplitude mapping, several gashydrate prospects were identified in the Alaminos Canyon (AC) area of the Gulf of Mexico. Two locations were drilled as part of the Gulf of MexicoGasHydrate Joint Industry Project Leg II (JIP Leg II) in May of 2009 and a comprehensive set of logging-while-drilling (LWD) logs were acquired at each well site. LWD logs indicated that resistivity in the range of ~2 ohm-m and P-wave velocity in the range of ~1.9 km/s were measured in the target sand interval between 515 and 645 feet below sea floor. These values were slightly elevated relative to those measured in the sediment above and below the target sand. However, the initial well log analysis was inconclusive regarding the presence of gashydrate in the logged sand interval, mainly because largewashouts caused by drilling in the target interval degraded confidence in the well log measurements. To assess gashydratesaturations in the sedimentary section drilled in the Alaminos Canyon 21B (AC21-B) well, a method of compensating for the effect of washouts on the resistivity and acoustic velocities was developed. The proposed method models the washed-out portion of the borehole as a vertical layer filled with sea water (drilling fluid) and the apparent anisotropic resistivity and velocities caused by a vertical layer are used to correct the measured log values. By incorporating the conventional marine seismic data into the well log analysis, the average gashydratesaturation in the target sand section in the AC21-Bwell can be constrained to the range of 8–28%, with 20% being our best estimate.

  20. Electric Power Regulation in Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Landa, J V [Universidad Nacional Autonoma de Mexico, Mexico City (Mexico)

    1994-12-31

    The history of the electrical power sector in Mexico, the prominent role that government plays in the generation, transformation, distribution and supply of electrical power, and the implications of the North American Free Trade Agreement (NAFTA) for this sector were summarized. The slow pace of the Mexican electricity sector in achieving cost efficiency through pricing policy was criticized, and the issue of regulation versus deregulation of the electricity sector was examined in the context of NAFTA, emphasizing the contradiction between the idea of international trade and a highly regulated industry. Revisions of the original constitutional article to exclude electrical power generation from governmental control and to allow market mechanisms and competition to lower costs and increase efficiency was recommended.It was considered a pre-condition to a stable balance between competition and energy efficient environmentally friendly practices.

  1. An Energy Overview of Mexico

    International Nuclear Information System (INIS)

    2003-01-01

    The DOE Office of Fossil Energy is maintaining a web site that is meant to provide useful business- and energy-related information about countries and regions of the world for exporters, project developers, and researchers. The site consists of more than 130 country pages (organized into seven different world regions), with each country page having its own set of links to information sources about that country. There are also more than 30 Country Energy Overviews at the web site -- each of these is a comprehensive review of a specific country's entire energy situation, including sections on Energy Policy, Oil, Natural Gas, Coal, Hydroelectric/Renewables, Nuclear Power, Energy Transmission Infrastructure, Electricity, Electric Industry Overview, Environmental Activities, Privatization, Trade, and Economic Situation. The specific country highlighted in this Country Energy Overview is Mexico. The site is designed to be dynamic. Updates to the overviews will be made as need and resources permit

  2. Gamma irradiation service in Mexico

    International Nuclear Information System (INIS)

    Liceaga C, G.; Martinez A, L.; Mendez T, D.; Ortiz A, G.; Olvera G, R.

    1997-01-01

    In 1980 it was installed in Mexico, on the National Institute of Nuclear Research, an irradiator model J S-6500 of a canadian manufacture. Actually, this is the greatest plant in the Mexican Republic that offers a gamma irradiation process at commercial level to diverse industries. However, seeing that the demand for sterilize those products were not so much as the irradiation capacity it was opted by the incursion in other types of products. During 17 years had been irradiated a great variety of products grouped of the following form: dehydrated foods, disposable products for medical use, cosmetics, medicaments, various. Nowadays the capacity of the irradiator is saturated virtue of it is operated the 24 hours during the 365 days of the year and only its operation is suspended by the preventive and corrective maintenance. However, the fresh food market does not be attended since this irradiator was designed for doses greater than 10 kGy (1.0 Mrad)

  3. [Fertility and health in Mexico].

    Science.gov (United States)

    Urbina-Fuentes, M; Echánove-Fernández, E

    1989-01-01

    Fertility, health, and family planning are not independent factors, but rather involve a series of biological and social mechanisms in close interaction with one another. The impact that a high fertility rate has on health is reflected mainly in a rise in the rates of maternal and child mortality. Similarly, fertility has a greater negative effect upon the health of groups characterized by high reproductive risk, high parity, short intergenesic intervals, and unwanted pregnancies. On the other hand, family planning -and specifically the use of contraceptive methods-helps to achieve a lowering of the fertility rate and also has a positive effect on maternal-child health. This situation can be observed in the case of Mexico, where fertility rates and tendencies, as well as maternal and child mortality, have been reduced during the past decade.

  4. [Migratory circuits in western Mexico].

    Science.gov (United States)

    Durand, J

    1986-11-01

    The author examines patterns of internal and international migration in western Mexico. "Drawing on data from different sources and statistics, the essay demonstrates the importance of both types of migration, the changes in endogenous and exogenous factors which have affected the life and the migratory patterns of the population of this region. The migratory circuit being a flow not only of persons, but of goods and capital as well, the cities, specifically that of Guadalajara, have a strategic importance. They fulfill various functions and have become the backbone of the migratory process: they serve as centers for attracting and 'hosting' internal migrants as well as places of origin for other migrants; jumping-off points for international migrants; and the milieu in which many returning migrants of rural origin settle." (SUMMARY IN ENG AND FRE) excerpt

  5. Validation of the Spanish Version of the Emotional Skills Assessment Process (ESAP) with College Students in Mexico

    Science.gov (United States)

    Teliz Triujeque, Rosalia

    2009-01-01

    The major purpose of the study was to determine the construct validity of the Spanish version of the Emotional Skills Assessment Process (ESAP) in a targeted population of agriculture college students in Mexico. The ESAP is a self assessment approach that helps students to identify and understand emotional intelligence skills relevant for…

  6. Magnetic resonance imaging in Mexico

    Science.gov (United States)

    Rodriguez, A. O.; Rojas, R.; Barrios, F. A.

    2001-10-01

    MR imaging has experienced an important growth worldwide and in particular in the USA and Japan. This imaging technique has also shown an important rise in the number of MR imagers in Mexico. However, the development of MRI has followed a typical way of Latin American countries, which is very different from the path shown in the industrialised countries. Despite the fact that Mexico was one the very first countries to install and operate MR imagers in the world, it still lacks of qualified clinical and technical personnel. Since the first MR scanner started to operate, the number of units has grown at a moderate space that now sums up approximately 60 system installed nationwide. Nevertheless, there are no official records of the number of MR units operating, physicians and technicians involved in this imaging modality. The MRI market is dominated by two important companies: General Electric (approximately 51%) and Siemens (approximately 17.5%), the rest is shared by other five companies. According to the field intensity, medium-field systems (0.5 Tesla) represent 60% while a further 35% are 1.0 T or higher. Almost all of these units are in private hospitals and clinics: there is no high-field MR imagers in any public hospital. Because the political changes in the country, a new public plan for health care is still in the process and will be published soon this year. This plan will be determined by the new Congress. North American Free Trade Agreement (NAFTA) and president Fox. Experience acquired in the past shows that the demand for qualified professionals will grow in the new future. Therefore, systematic training of clinical and technical professionals will be in high demand to meet the needs of this technique. The National University (UNAM) and the Metropolitan University (UAM-Iztapalapa) are collaborating with diverse clinical groups in private facilities to create a systematic training program and carry out research and development in MRI

  7. Isotropic, anisotropic, and borehole washout analyses in Gulf of Mexico Gas Hydrate Joint Industry Project Leg II, Alaminos Canyon well 21-A

    Science.gov (United States)

    Lee, Myung W.

    2012-01-01

    Through the use of three-dimensional seismic amplitude mapping, several gas hydrate prospects were identified in the Alaminos Canyon area of the Gulf of Mexico. Two of the prospects were drilled as part of the Gulf of Mexico Gas Hydrate Joint Industry Program Leg II in May 2009, and a suite of logging-while-drilling logs was acquired at each well site. Logging-while-drilling logs at the Alaminos Canyon 21–A site indicate that resistivities of approximately 2 ohm-meter and P-wave velocities of approximately 1.9 kilometers per second were measured in a possible gas-hydrate-bearing target sand interval between 540 and 632 feet below the sea floor. These values are slightly elevated relative to those measured in the hydrate-free sediment surrounding the sands. The initial well log analysis is inconclusive in determining the presence of gas hydrate in the logged sand interval, mainly because large washouts in the target interval degraded well log measurements. To assess gas-hydrate saturations, a method of compensating for the effect of washouts on the resistivity and acoustic velocities is required. To meet this need, a method is presented that models the washed-out portion of the borehole as a vertical layer filled with seawater (drilling fluid). Owing to the anisotropic nature of this geometry, the apparent anisotropic resistivities and velocities caused by the vertical layer are used to correct measured log values. By incorporating the conventional marine seismic data into the well log analysis of the washout-corrected well logs, the gas-hydrate saturation at well site AC21–A was estimated to be in the range of 13 percent. Because gas hydrates in the vertical fractures were observed, anisotropic rock physics models were also applied to estimate gas-hydrate saturations.

  8. Initialized Fractional Calculus

    Science.gov (United States)

    Lorenzo, Carl F.; Hartley, Tom T.

    2000-01-01

    This paper demonstrates the need for a nonconstant initialization for the fractional calculus and establishes a basic definition set for the initialized fractional differintegral. This definition set allows the formalization of an initialized fractional calculus. Two basis calculi are considered; the Riemann-Liouville and the Grunwald fractional calculi. Two forms of initialization, terminal and side are developed.

  9. Protected Areas Database for New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The Protected Areas Database of the United States (PAD-US) is a geodatabase, managed by USGS GAP, that illustrates and describes public land ownership, management...

  10. Mexico East-West Deflections (DMEX97)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This 2' surface deflection of the vertical grid for Mexico, and North-Central is the DMEX97 model. The computation used about one million terrestrial and marine...

  11. Building the gas sector in Mexico

    International Nuclear Information System (INIS)

    Navarrete, J.E.

    1996-01-01

    Hydrocarbon reserves in Mexico, ranked 8th in the world, were discussed. On January 1, 1996, Mexico's hydrocarbon proven reserves were 62.1 billion barrels ( a decline of some 10 billion barrels since 1984). Of this 48.8 billion corresponded to crude oil and 13.3 billion to natural gas. Mexico's natural gas pipeline network includes 10,280 kilometres in transmission and 2,211 kilometres in distribution, concentrated along the Gulf of Mexico and in the central and northern regions of the country. A new regulatory framework for natural gas, passed in Congress in 1995, was outlined. The new amendments were designed to strengthen the natural gas industry through private investment in the storage, transportation and distribution of natural gas. Stages for third party access were identified. Increased North American regional integration by interconnections between Mexican, American and Canadian pipeline networks, and the effects of such integration on investments, were examined. figs

  12. West Nile virus infection of birds, Mexico.

    Science.gov (United States)

    Guerrero-Sánchez, Sergio; Cuevas-Romero, Sandra; Nemeth, Nicole M; Trujillo-Olivera, María Teresa Jesús; Worwa, Gabriella; Dupuis, Alan; Brault, Aaron C; Kramer, Laura D; Komar, Nicholas; Estrada-Franco, José Guillermo

    2011-12-01

    West Nile virus (WNV) has caused disease in humans, equids, and birds at lower frequency in Mexico than in the United States. We hypothesized that the seemingly reduced virulence in Mexico was caused by attenuation of the Tabasco strain from southeastern Mexico, resulting in lower viremia than that caused by the Tecate strain from the more northern location of Baja California. During 2006-2008, we tested this hypothesis in candidate avian amplifying hosts: domestic chickens, rock pigeons, house sparrows, great-tailed grackles, and clay-colored thrushes. Only great-tailed grackles and house sparrows were competent amplifying hosts for both strains, and deaths occurred in each species. Tecate strain viremia levels were higher for thrushes. Both strains produced low-level viremia in pigeons and chickens. Our results suggest that certain avian hosts within Mexico are competent for efficient amplification of both northern and southern WNV strains and that both strains likely contribute to bird deaths.

  13. Migratory Bird Joint Ventures of New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — A joint venture is a self-directed partnership of agencies, organizations, corporations, tribes, or individuals that has formally accepted the responsibility of...

  14. New Mexico Populated Places (GNIS), 2009

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The Geographic Names Information System (GNIS) actively seeks data from and partnerships with Government agencies at all levels and other interested organizations....

  15. Mexico North-South Deflections (DMEX97)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This 2' surface deflection of the vertical grid for Mexico, and North-Central is the DMEX97 model. The computation used about one million terrestrial and marine...

  16. HSIP New Mexico State Government Buildings

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset includes buildings occupied by the headquarters of cabinet level state government executive departments, legislative offices buildings outside of the...

  17. Landscape Conservative Cooperatives for New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Landscape conservation cooperatives (LCCs) are conservation-science partnerships between the U.S. Fish and Wildlife Service, U.S. Geological Survey (USGS), and other...

  18. Level III Eco Regions for New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Ecoregions by state were extracted from the seamless national shapefile. Ecoregions denote areas of general similarity in ecosystems and in the type, quality, and...

  19. Sustainability analysis of agave production in Mexico

    NARCIS (Netherlands)

    Ibarrola Rivas, Maria Jose

    2010-01-01

    Worldwide food production is done in different types of agricultural production systems. The main difference is whether it is an intensive or extensive system. The agave production in Mexico has been developed in these two different ways. Firstly, agave f

  20. Gulf of Mexico Ecosystem Status Report

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Gulf of Mexico is one of the most ecologically and economically valuable marine ecosystems in the world and is affected by a variety of natural and anthropogenic...

  1. Gulf of Mexico Nutrient, carbon, CTD data

    Data.gov (United States)

    U.S. Environmental Protection Agency — Gulf of Mexico cruise, nearshore and CTD data collected by the USEPA during 2002 - 2008. This dataset is associated with the following publications: Pauer , J., T....

  2. New Mexico County Boundaries (2010 Census)

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  3. HSIP Correctional Institutions in New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Jails and Prisons (Correctional Institutions). The Jails and Prisons sub-layer is part of the Emergency Law Enforcement Sector and the Critical Infrastructure...

  4. HSIP Law Enforcement Locations in New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Law Enforcement Locations Any location where sworn officers of a law enforcement agency are regularly based or stationed. Law Enforcement agencies "are publicly...

  5. Level IV Eco Regions for New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Ecoregions by state were extracted from the seamless national shapefile. Ecoregions denote areas of general similarity in ecosystems and in the type, quality, and...

  6. A new Proposal to Mexico Valley Zonification

    Science.gov (United States)

    Flores-Estrella, H. C.; Yussim, S.; Lomnitz, C.

    2004-12-01

    The effects of the Michoacan earthquake (19th September, 1985, Mw 8.1) in Mexico City caused a significant change in the political, social and scientific history, as it was considered the worst seismic disaster ever lived in Mexico. Since then, numerous efforts have been made to understand and determine the parameters that caused the special features registered. One of these efforts had began on 1960 with the work by Marsal and Masari, who published the Mexico Valley seismological and geotechnical zonification (1969), based on gravimetric and shallow borehole data. In this work, we present a revision of the studies that proposed the zonification, a description of the valley geology, and basing on it we propose a new zonification for Mexico Valley.

  7. 2013 Gulf of Mexico SPCE angler survey

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This survey provides economic data related to marine recreational fishing in the Gulf of Mexico. The data collected include preference and opinion information...

  8. Southeast Gulf of Mexico Sperm Whale Study

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Large vessel surveys were conducted during the summers of 2012 and 2014 in the southeastern Gulf of Mexico north of the Dry Tortugas. Data were collected on the...

  9. Historical account of venereal diseases in Mexico.

    OpenAIRE

    Conde-Glez, C J; Calderón, E; Juárez-Figueroa, L; Hernández-Avila, M

    1993-01-01

    This paper reviews the history of sexually acquired diseases in Mexico. It is divided into four major chronological sections which discuss social attitudes and values, the development of services and of official policy, and historical epidemiology.

  10. New Mexico, 2010 Census American Indian

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The TIGER/Line Files are shapefiles and related database files (.dbf) that are an extract of selected geographic and cartographic information from the U.S. Census...

  11. Predictors of needle exchange program utilization during its implementation and expansion in Tijuana, Mexico.

    Science.gov (United States)

    Smith, Danielle M; Werb, Dan; Abramovitz, Daniela; Magis-Rodriguez, Carlos; Vera, Alicia; Patterson, Thomas L; Strathdee, Steffanie A

    2016-03-01

    Until the early 2000s, there was only one needle exchange program (NEP) offered in Mexico. In 2004, the second Mexican NEP opened in Tijuana, but its utilization has not been studied. We studied predictors of initiating NEP during its early expansion in Tijuana, Mexico. From April 2006 to April 2007, people who inject drugs (PWID) residing in Tijuana who had injected within the last month were recruited using respondent-driven sampling. Weighted Poisson regression incorporating generalized estimating equations was used to identify predictors of initiating NEP, while accounting for correlation between recruiter and recruits. NEP uptake increased from 20% at baseline to 59% after 6 months. Among a subsample of PWID not accessing NEP at baseline (n = 480), 83% were male and median age was 37 years (Interquartile Range: 32-43). At baseline, 4.4% were HIV-infected and 5.9% had syphilis titers >1:8. In multivariate models, factors associated with NEP initiation (p 2500 pesos/month (ARR: .66); and reporting needle sharing (ARR: .71). Uptake of NEP expansion in Tijuana was vigorous among PWID. We identified a range of factors that influenced the likelihood of NEP initiation, including police interaction. These findings have important implications for the scale-up of NEP in Mexico. © American Academy of Addiction Psychiatry.

  12. Bilateral relations Mexico-Korea today

    Directory of Open Access Journals (Sweden)

    Cecilia Ramírez Figueroa

    2007-06-01

    Full Text Available The ambassador of the Republic of Korea in Mexico, Sr. Cho Kyuhyung, remember us the first century if the korean migration to Mexico. In this one hundred years ours countries have approched and lauched a joint work with great value. They have worked for growth of trade and investment, They have promoted cultural and scientific exchanges. They have worked, especially in the enrichment of a friendship that will surely last for many more years.

  13. Epidemic Risk from Cholera Introductions into Mexico

    OpenAIRE

    Moore, Sean M.; Shannon, Kerry L.; Zelaya, Carla E.; Azman, Andrew S.; Lessler, Justin

    2014-01-01

    Stemming from the 2010 cholera outbreak in Haiti, cholera transmission in Hispaniola continues with over 40,000 cases in 2013. The presence of an ongoing cholera outbreak in the region poses substantial risks to countries throughout the Americas, particularly in areas with poor infrastructure. Since September 9, 2013 nearly 200 cholera cases have been reported in Mexico, as a result of introductions from Hispaniola or Cuba. There appear to have been multiple introductions into Mexico resultin...

  14. China in Mexico: More Opportunity than Risk

    Science.gov (United States)

    2011-10-17

    factory.55 Mexico’s percent of Ford’s U.S. car production went from 11.8 in 2006 to 16 percent in 2008.56 Nissan , Mazda, Volkswagen, Audi, Toyota ... compared to the time lag (and increased cost) of over a week required to transport products from China to the United States. Even in the well...and Honda also produce cars in Mexico, all increasing investment and manufacturing facilities.57 China, in selecting Mexico as a major FDI

  15. Water Scarcity and Water Policy in Mexico

    OpenAIRE

    Facchini, Gianluca

    2009-01-01

    This thesis addresses the possible solutions to control demand and supply of water for a sustainable environment in Mexico, along with a detailed analyses of economic implications related to the water sector. At the same time it focuses on the opportunities and constraints to improve the use of water and the allocation in the agricultural sector, by a system of transferable water-use permits. Actual examples are provided nationwide to the current situation in Mexico, focusing on problems rela...

  16. The Zapatista Social Netwar in Mexico

    Science.gov (United States)

    1998-01-01

    on the Internet. 4From a statement by Subcommandante Marcos, March 4, 1994, as reported by the Academia Mexicana de Derechos Humanos , Special...Indigenas de Mexico, Mexico City: Comisiön Nacional de Derechos Humanos , 1995. Evan, William M., "An Organization-Set Model of Interorganizational...City: Comision Nacional de Dere- chos Humanos , 1995. Meisel, James, The Fall of the Republic: Military Revolt in France, Ann Arbor: University of

  17. The economic impact of the Department of Energy on the state of New Mexico fiscal year 1997

    Energy Technology Data Exchange (ETDEWEB)

    Lansford, R.R.; Nielsen, T.G.; Schultz, J. [New Mexico State Univ., Las Cruces, NM (United States); Adcock, L.D.; Gentry, L.M. [Dept. of Energy, Albuquerque, NM (United States). Albuquerque Operations Office; Ben-David, S. [Univ. of New Mexico, Albuquerque, NM (United States). Dept. of Economics; Temple, J. [Temple (John), Albuquerque, NM (United States)

    1998-05-29

    The US Department of Energy (DOE) provides a major source of economic benefits in New Mexico. The agency`s far-reaching economic influence within the state is the focus of this report. Economic benefits arising from the various activities and functions of both DOE and its contractors have accrued to the state continuously for over 50 years. For several years, DOE/Albuquerque Operations Office (AL) and New Mexico State University (NMSU) have maintained inter-industry, input-output modeling capabilities to assess DOE`s impacts on the state of New Mexico and the other substate regions most directly impacted by DOE activities. One of the major uses of input-output techniques is to assess the effects of developments initiated outside the economy such as federal DOE monies that flow into the state, on an economy. The information on which the models are based is updated periodically to ensure the most accurate depiction possible of the economy for the period of reference. For this report, the reference periods are Fiscal Year (FY) 1996 and FY 1997. Total impacts represents both direct and indirect impacts (respending by business), including induced (respending by households) effects. The standard multipliers used in determining impacts result from the inter-industry, input-output models uniquely developed for New Mexico. This report includes seven main sections: (1) introduction; (2) profile of DOE activities in New Mexico; (3) DOE expenditure patterns; (4) measuring DOE/New Mexico`s economic impact; (5) technology transfer within the federal labs funded by DOE/New Mexico; (6) glossary of terms; and (7) technical appendix containing a description of the model. 9 figs., 19 tabs.

  18. Electric power and environment in Mexico

    International Nuclear Information System (INIS)

    Quintanilla, J.

    1997-01-01

    This volume is one of the three resulting volumes about the project named Document analysis and prospective organized by the National Autonomous University of Mexico (UNAM) through it University Energy Program (PUE). It is a non-periodical publication collection of the variable content and extent that as a whole constitutes an information heritage and an original contribution about the energy problematic as International level as at the country context and the University activities. In this book the manners of producing electrical energy are discussed, so how satisfying the growing necessities of this energy in Mexico without contaminating environment and how doing rational and efficient use of energy. The content of each document of this book is however exclusive responsibility of authors, as in the information as in their told opinions. The following papers were presented: 1) Hydroelectricity, soils use and water management. 2) The electric generation in Mexico and its environmental impacts: Past, present and future. 3) The nucleo electricity and the radioactive materials management. 4) Exposure to electromagnetic fields and its association with leukemia in children. 5) The electric power in Mexico and the supportable development. 6) Potential of electric generation at great scale with eolic energy in Mexico. 7) Toward an electric generation scheme distributed with non-conventional energies. 8) Renewable sources of energy in Mexico at the Century 21. (Author)

  19. Mexico joins the venture: Joint Implementation and Greenhouse Gas Emissions

    Energy Technology Data Exchange (ETDEWEB)

    Imaz, M.; Gay, C.; Friedmann, R.; Goldberg, B.

    1998-11-01

    Joint Implementation (JI) and its pilot phase of Activities Implemented Jointly (AIJ) are envisioned as an economic way of reducing global emissions of greenhouse gases. This paper draws upon the Mexican experience with AIJ to identify Mexican concerns with AIJ/JI and proposed solutions to these. Three approved Mexican AIJ projects (Ilumex, Scolel Te, and Salicornia) are described in detail. The Ilurnex project promotes the use of compact fluorescent lamps in Mexican homes of the States of Jalisco and Nuevo Leon, to reduce electric demand. Scolel Te is a sustainable forest management project in Chiapas. Salicornia examines the potential for carbon sequestration with a Halophyte-based crop irrigated with saline waters in Sonora. These three projects are reviewed to clarify the issues and concerns that Mexico has with AIJ and JI and propose measures to deal with them. These initial Mexican AIJ projects show that there is a need for creation of standard project evaluation procedures, and criteria and institutions to oversee project design, selection, and implementation. Further JI development will be facilitated by national and international clarification of key issues such as additionality criteria, carbon-credit sharing, and valuation of non-GHG environmental and/or social benefits and impacts for AIJ projects. Mexico is concerned that JI funding could negatively impact official development assistance or that OECD countries will use JI to avoid taking significant GHG mitigation actions in their own countries. The lack of carbon credit trading in the AIJ stage must be removed to provide useful experience on how to share carbon credits. National or international guidelines are needed to ensure that a portion of the carbon credits is allocated to Mexico.

  20. Nuclear desalination for the northwest of Mexico

    International Nuclear Information System (INIS)

    Ortega C, R. F.

    2008-01-01

    The IMPULSA project of the Engineering Institute of UNAM, it has dedicated from the year 2005 to the study and development of new desalination technologies of seawater with renewable energies. The objective is to form a group of expert engineers and investigators in the desalination topics able to transform their scientific knowledge in engineering solutions, with a high grade of knowledge of the environment and the renewable energies. In the middle of 2007 was took the initiative in the IMPULSA project to study the nuclear desalination topic. It is evident that before the high cost of the hydrocarbons and its high environmental impact, the nuclear generation alternative of energy becomes extremely attractive, mainly for desalination projects of seawater of great size. The Northwest of Mexico is particularly attractive as the appropriate site for one nuclear desalination plant of great size given its shortage of drink water and the quick growth of its population; as well as its level of tourist, agricultural and industrial activity. In this study was revised the state of the art of the nuclear desalination on the world and it is simulated some couplings and operation forms of nuclear reactors and desalination units, from the thermodynamic and economic viewpoint with the purpose of identifying the main peculiarities of this technology. The objective of the study was to characterize several types and sizes of nuclear reactors of the last generation that could be couple to a desalination technology as multi-stage distillation, type flash distillation or inverse osmosis. It is used for this effect the DEEP 3.1 program of the IAEA to simulate the coupling and to carry out an economic preliminary evaluation. Was found cost very competitive of 0.038-0.044 US$/kWh for the electric power production and 0.60 to 0.77 US$/m 3 for the drink water produced, without including the water transport cost or the use of carbon certificates. (Author)

  1. Diversity of amphibians and reptiles associated with grasslands of Janos-Casas Grandes, Chihuahua, Mexico (La diversidad de anfibios y reptiles asociada a los pastizales de Janos-Casas Grandes, Chihuahua, Mexico)

    Science.gov (United States)

    Georgina Santos-Barrera; Jesus Pacheco-Rodriguez

    2006-01-01

    Prairie-dog (Cynomys ludovicianus) colonies in northwest Chihuahua, Mexico, have been of great significance not only in initiating protection programs for the species but also in learning about the biological diversity (flora and fauna) of the natural grasslands of Janos-Casas Grandes, Chihuahua. Therefore a study of the herpetological fauna within the prairie-dog...

  2. The personal dosimetry in Mexico; La dosimetria personal en Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Salazar, M.A. [Proxtronics/ Asesoria Integral en Dosimetria Termoluminiscente S.A. de C.V., Canal de Miramontes 2030-14, Col. Educacion, 04400 Mexico D.F. (Mexico)]. e-mail: aidtsa@avantel.net

    2006-07-01

    The Personal Dosimetry in Mexico, has an approximately 30 year-old history; and it had been and it is at the moment, one of the more important resources with which the personnel that works with ionizing radiation sources counts for its protection. The Personal Dosimetry begins with the film dosimetry, technique that even continues being used at the present time by some users, and the main reason of its use is for economic reasons. At the moment this technique, it has been surpassed, by the Thermoluminescent dosimetry, which has taken a lot of peak, mainly by the technological development with which it is counted at the present time; what has given as a result that this technique becomes tip technology; that supported in the characteristic of the used materials, as the handling and processing of the information associated with the new PC, digitizer cards, software etc, what has allowed increases it potential. In this work the current necessities of the market are presented as well as an analysis of the future real necessities in Mexico, at national level, the companies that provide this service and that they spread to satisfy this necessity of the market, including the different used technologies are also mentioned. The application ranges, at the same time, of the advantages and disadvantages of the different systems of Personal Dosimetry in the market. The companies that at the moment provide the service of Personal Dosimetry, its use materials and equipment in indistinct form, for the monitoring of gamma radiation, beta particles, different qualities of x-ray radiation, and sometimes neutrons. The monitoring of the exposed personnel at the diverse sources of ionizing radiation mentioned is carried out in many occasions without having with the materials (detectors), neither the appropriate infrastructure and therefore without the quality control that guarantees a correct evaluation of the dose equivalent, as a result of the exposure to the ionizing radiations; it

  3. The accountability imperative for quantifying the uncertainty of emission forecasts: evidence from Mexico

    International Nuclear Information System (INIS)

    Puig, Daniel; Bakhtiari, Fatemeh; Morales-Napoles, Oswaldo; Landa Rivera, Gissela

    2017-01-01

    Governmental climate change mitigation targets are typically developed with the aid of forecasts of greenhouse-gas emissions. The robustness and credibility of such forecasts depends, among other issues, on the extent to which forecasting approaches can reflect prevailing uncertainties. We apply a transparent and replicable method to quantify the uncertainty associated with projections of gross domestic product growth rates for Mexico, a key driver of greenhouse-gas emissions in the country. We use those projections to produce probabilistic forecasts of greenhouse-gas emissions for Mexico. We contrast our probabilistic forecasts with Mexico's governmental deterministic forecasts. We show that, because they fail to reflect such key uncertainty, deterministic forecasts are ill-suited for use in target-setting processes. We argue that (i) guidelines should be agreed upon, to ensure that governmental forecasts meet certain minimum transparency and quality standards, and (ii) governments should be held accountable for the appropriateness of the forecasting approach applied to prepare governmental forecasts, especially when those forecasts are used to derive climate change mitigation targets. (authors)

  4. Co-control of urban air pollutants and greenhouse gases in Mexico City.

    Science.gov (United States)

    West, J Jason; Osnaya, Patricia; Laguna, Israel; Martínez, Julia; Fernández, Adrián

    2004-07-01

    This study addresses the synergies of mitigation measures to control urban air pollutant and greenhouse gas (GHG) emissions, in developing integrated "co-control" strategies for Mexico City. First, existing studies of emissions reduction measures--PROAIRE (the air quality plan for Mexico City) and separate GHG studies--are used to construct a harmonized database of options. Second, linear programming (LP) is developed and applied as a decision-support tool to analyze least-cost strategies for meeting co-control targets for multiple pollutants. We estimate that implementing PROAIRE measures as planned will reduce 3.1% of the 2010 metropolitan CO2 emissions, in addition to substantial local air pollutant reductions. Applying the LP, PROAIRE emissions reductions can be met at a 20% lower cost, using only the PROAIRE measures, by adjusting investments toward the more cost-effective measures; lower net costs are possible by including cost-saving GHG mitigation measures, but with increased investment. When CO2 emission reduction targets are added to PROAIRE targets, the most cost-effective solutions use PROAIRE measures for the majority of local pollutant reductions, and GHG measures for additional CO2 control. Because of synergies, the integrated planning of urban-global co-control can be beneficial, but we estimate that for Mexico City these benefits are often small.

  5. Where Do Mexico and Chile Stand on Inclusive Education? Short Title: Inclusion in Mexico and Chile

    Science.gov (United States)

    García-Cedillo, Ismael; Romero-Contreras, Silvia; Ramos-Abadie, Liliana

    2015-01-01

    This paper discusses the background, current situation and challenges of educational integration and inclusive education in Mexico and Chile. These countries obtained similar low results on the academic achievement of their students (Mexico last and Chile second last) among OECD countries; and above average scores, among Latin-American countries.…

  6. Trace gas and particle emissions from domestic and industrial biofuel use and garbage burning in central Mexico

    Science.gov (United States)

    T. J. Christian; R. J. Yokelson; B. Cardenas; L. T. Molina; G. Engling; S.-C. Hsu

    2010-01-01

    In central Mexico during the spring of 2007 we measured the initial emissions of 12 gases and the aerosol speciation for elemental and organic carbon (EC, OC), anhydrosugars, Cl-, NO-3 , and 20 metals from 10 cooking fires, four garbage fires, three brick making kilns, three charcoal making kilns, and two crop residue fires. Global biofuel use has been...

  7. Use of deuterium and oxygen-18 in hydrological problems at Villa de Reyes, S.L.P. Mexico

    International Nuclear Information System (INIS)

    Morales, P.; Castillo C, R.

    1983-01-01

    A survey of an initial study in order to understand the general behaviour of ground water at Villa de Reyes, S.L.P. Mexico is presented. Deuterium and oxygen results are discussed and two geothermometers were used in order to search for a geothermal area. (author)

  8. Trace gas and particle emissions from domestic and industrial biofuel use and garbage burning in central Mexico

    Science.gov (United States)

    T. J. Christian; R. J. Yokelson; B. Cardenas; L. T. Molina; G. Engling; S.-C. Hsu

    2009-01-01

    In central Mexico during the spring of 2007 we measured the initial emissions of 12 gases and the aerosol speciation for elemental and organic carbon (EC, OC), anhydrosugars, Cl-, NO-3 , and 20 metals from 10 cooking fires, four garbage fires, three brick making kilns, three charcoal making kilns, and two crop residue fires. Biofuel use has been estimated at over 2600...

  9. Executive Succession and Institutional Change: A Case Study of the University of New Mexico, 1967-1972.

    Science.gov (United States)

    Bjork, Lars G.

    The history of the University of New Mexico during 1967-1972, when a new president was appointed, is examined. Attention is focused primarily on the environmental milieu relating to federal support of university research and the president's leadership initiative in establishing the Office of the Vice President for Research. In reviewing…

  10. Statistical properties of the surface velocity field in the northern Gulf of Mexico sampled by GLAD drifters

    NARCIS (Netherlands)

    Mariano, A.J.; Ryan, E.H.; Huntley, H.S.; Laurindo, L.C.; Coelho, E.; Ozgokmen, TM; Berta, M.; Bogucki, D; Chen, S.S.; Curcic, M.; Drouin, K.L.; Gough, M; Haus, BK; Haza, A.C.; Hogan, P; Iskandarani, M; Jacobs, G; Kirwan Jr., A.D.; Laxague, N; Lipphardt Jr., B.; Magaldi, M.G.; Novelli, G.; Reniers, A.J.H.M.; Restrepo, J.M.; Smith, C; Valle-Levinson, A.; Wei, M.

    2016-01-01

    The Grand LAgrangian Deployment (GLAD) used multiscale sampling and GPS technology to observe time series of drifter positions with initial drifter separation of O(100 m) to O(10 km), and nominal 5 min sampling, during the summer and fall of 2012 in the northern Gulf of Mexico. Histograms of the

  11. English Language Teaching in Public Primary Schools in Mexico: The Practices and Challenges of Implementing a National Language Education Program

    Science.gov (United States)

    Ramírez Romero, José Luis; Sayer, Peter; Pamplón Irigoyen, Elva Nora

    2014-01-01

    Over the past 15?years, many state governments in Mexico have initiated local programs to introduce English at the primary school level. In 2009, the Mexican Ministry of Education formalized the "Programa Nacional de Inglés en Educación Básica" (PNIEB) as part of the national curriculum, based on the argument that increasing the number…

  12. The Impact of the Chile Intervention on the Food Served in Head Start Centers in Rural New Mexico

    Science.gov (United States)

    Morshed, Alexandra B.; Davis, Sally M.; Keane, Patricia C.; Myers, Orrin B.; Mishra, Shiraz I.

    2016-01-01

    Background: The Child Health Initiative for Lifelong Eating and Exercise is a multicomponent obesity-prevention intervention, which was evaluated among Head Start (HS) centers in American Indian and predominantly Hispanic communities in rural New Mexico. This study examines the intervention's foodservice outcomes: fruits, vegetables, whole grains,…

  13. Systemic Competitiveness of SMEs in Mexico City, Mexico

    Directory of Open Access Journals (Sweden)

    Maria Luisa Saavedra García

    2015-07-01

    Full Text Available The objective of this work was to apply the model of systemic competitiveness, SMEs in Mexico City. Developing four levels of competitiveness: macro level (economic environment, meso level (regional environment, Level Goal (Environment Socioeconomic and micro Level (internal factors. Data collection was done through fieldwork and archival research. The main findings are among the major strengths of the economic environment: high level of gross domestic product, high labor productivity and fiscal autonomy, the main weaknesses: the unions and the unemployment rate; meanwhile stand between foreign investment opportunities between threats and insecurity, corruption and difficulty in business transactions. In the regional setting a positive and 1 perfect relationship between the number of economic units and per capita GDP was found. With regard to socio-cultural factors, presents lower levels of poverty and unemployment to the rest of the country. Finally, at the micro level, the competitiveness of SMEs is in direct relation to the size of the company and the industry sector shows higher competitiveness trade and services sectors.

  14. Initial performance parameters on FXR

    International Nuclear Information System (INIS)

    Kulke, B.; Innes, T.G.; Kihara, R.; Scarpetti, R.D.

    1982-01-01

    Construction of the new flash x-ray induction LINAC (FXR) at Lawrence Livermore National Laboratory has been completed. Initial tuning of the machine has produced stable current pulses in excess of 2 kA at the design energy of 20 MeV, with an 80 ns FWHM pulse width, producing single-pulse radiation doses near 500 Roentgen at one meter from the target. The electronic spot size on the bremsstrahlung target is estimated at 3 to 5 mm. In this paper we will discuss the basic FXR design; running-in and tuning of the machine; emittance measurements; beam stability; switch gap synchronization; and measurements of the radiation dose and angular distribution

  15. The fabrication of nuclear fuel elements in Mexico

    International Nuclear Information System (INIS)

    Guerrero Morillo, H.L.

    1977-01-01

    The situation of nuclear electricity generation in Mexico in 1976 is described: two nuclear reactors were under construction but no definite programme on the type and start-up dates for the next power plants existed. However, the existence of a general plan on nuclear power plants is mentioned, which, according to the latest estimates, will provide 10,000MW installed by 1990. The national intention, as laid down in an appropriate Law, is to supply domestic nuclear fuel to the power reactors operating in the country, starting with the first reloading of the two BWRs at the first national station in Laguna Verde, required at the end of 1981 and 1982, respectively. Before this can be achieved and to provide the relatively small amounts of fuel elements for the two reactors, Mexico must adopt a strategy of fuel elements fabrication. The two main options are analysed: (1) to delay local fabrication until a national nuclear programme has been defined, meanwhile purchasing abroad the necessary initial cores and refuelling; (2) to start local fabrication of fuel elements as soon as possible in order to provide the first refuelling of the first unit of Laguna Verde, confronting the economic risks of such a decision with the advantages of immediate action. Both options are analysed in detail, comparing them especially from the economic point of view. Current information from potential licensors for design and manufacture are used in the analysis. (author)

  16. Drugs, Violence, and Trauma in Mexico and the USA

    Science.gov (United States)

    Puyana, Juan Carlos; Puyana, Juan Carlos Jacob; Rubiano, Andres Mariano; Montenegro, Jorge Hernan; Estebanez, Glyn O.; Sanchez, Alvaro Ignacio; Vega-Rivera, Felipe

    2017-01-01

    The impact of illicit drug markets on the occurrence of violence varies tremendously depending on many factors. Over the last years, Mexico and the USA have increased security border issues that included many aspects of drug-related trade and criminal activities. Mexico experienced only a small reduction in trauma deaths after the enforcement of severe crime reinforcement policies. This strategy in the war on drugs is shifting the drug market to other Central American countries. This phenomenon is called the ballooning effect, whereby the pressure to control illicit drug-related activities in one particular area forces a shift to other more vulnerable areas that leads to an increase in crime and violence. A human rights crisis characterized by suffering, injury, and death related to drug trafficking continues to expand, resulting in the exorbitant loss of lives and cost in productivity across the continent. The current climate of social violence in Central America and the illegal immigration to the USA may be partially related to this phenomenon of drug trafficking, gang violence, and crime. A health care initiative as an alternative to the current war approach may be one of the interventions needed to reduce this crisis. PMID:28329741

  17. Colorectal Cancer Incidence and Mortality Disparities in New Mexico

    International Nuclear Information System (INIS)

    Hoffman, R. M.; Gonzales, M.; Wiggins, C. L.; Hoffman, R. M.

    2014-01-01

    Previous analyses indicated that New Mexican Hispanics and American Indians (AI) did not experience the declining colorectal cancer (CRC) incidence and mortality rates observed among non-Hispanic whites (NHW). We evaluated more recent data to determine whether racial/ethnic differences persisted. Methods. We used New Mexico Surveillance Epidemiology and End Results data from 1995 to 2009 to calculate age-specific incidence rates and age-adjusted incidence rates overall and by tumor stage. We calculated mortality rates using National Center for Health Statistics’ data. We used join point regression to determine annual percentage change (APC) in age-adjusted incidence rates. Analyses were stratified by race/ethnicity and gender. Results. Incidence rates continued declining in NHW (APC −1.45% men, −1.06% women), while non significantly increasing for AI (1.67% men, 1.26% women) and Hispanic women (0.24%). The APC initially increased in Hispanic men through 2001 (3.33%, P = 0.06), before declining (−3.10%, P = 0,003). Incidence rates declined in NHW and Hispanics aged 75 and older. Incidence rates for distant-stage cancer remained stable for all groups. Mortality rates declined significantly in NHW and Hispanics. Conclusions. Racial/ethnic disparities in CRC persist in New Mexico. Incidence differences could be related to risk factors or access to screening; mortality differences could be due to patterns of care for screening or treatment.

  18. Gulf of Mexico soundscapes as indicators of ecological stressors

    Science.gov (United States)

    Sidorovskaia, N.; Li, K.; Tiemann, C.; Ackleh, A. S.; Tang, T.; Risbourg, J. H.

    2016-12-01

    Soundscapes in the Northern Gulf of Mexico are complex and represent a combination of anthropogenic noise (oil exploration and production, shipping, rig construction, etc.), bio-soundscapes (sound of marine mammals and fish), and geo-soundscapes (weather events, submarine landslides, distant earthquakes, natural gas seeps). We will discuss how Passive Acoustic Monitoring in the deep Gulf has been utilized during the past decade to study the soundscape variability on daily, monthly, and yearly timescales and what environmental information can be extracted from this variability. Isolation of bio-soundscapes, identification of their sources, and abundance estimates based on acoustic cues are used to track the recovery of marine mammal species after major ecological disasters, such as the recent 2010 oil spill. Association of acoustic activity of marine species with anthropogenic noise levels and other environmental variables can provide base data that can be used to build ecological models of habitat preferences for different marine species. Understanding how the variability of anthropogenic soundscapes correlates with marine species distributions is critically important for regional conservation and mitigation strategies. Such studies can also assist in forecasting the long-term ecosystem health status and ecosystem response to disturbances of different spatial and temporal extent, including slow variations associated with climate change. [This research was made possible in part by a grant from The Gulf of Mexico Research Initiative, and in part by funding provided by ONR and The Joint Industry Programme.

  19. The personal dosimetry in Mexico

    International Nuclear Information System (INIS)

    Salazar, M.A.

    2006-01-01

    The Personal Dosimetry in Mexico, has an approximately 30 year-old history; and it had been and it is at the moment, one of the more important resources with which the personnel that works with ionizing radiation sources counts for its protection. The Personal Dosimetry begins with the film dosimetry, technique that even continues being used at the present time by some users, and the main reason of its use is for economic reasons. At the moment this technique, it has been surpassed, by the Thermoluminescent dosimetry, which has taken a lot of peak, mainly by the technological development with which it is counted at the present time; what has given as a result that this technique becomes tip technology; that supported in the characteristic of the used materials, as the handling and processing of the information associated with the new PC, digitizer cards, software etc, what has allowed increases it potential. In this work the current necessities of the market are presented as well as an analysis of the future real necessities in Mexico, at national level, the companies that provide this service and that they spread to satisfy this necessity of the market, including the different used technologies are also mentioned. The application ranges, at the same time, of the advantages and disadvantages of the different systems of Personal Dosimetry in the market. The companies that at the moment provide the service of Personal Dosimetry, its use materials and equipment in indistinct form, for the monitoring of gamma radiation, beta particles, different qualities of x-ray radiation, and sometimes neutrons. The monitoring of the exposed personnel at the diverse sources of ionizing radiation mentioned is carried out in many occasions without having with the materials (detectors), neither the appropriate infrastructure and therefore without the quality control that guarantees a correct evaluation of the dose equivalent, as a result of the exposure to the ionizing radiations; it

  20. `A novel, spicy delicacy': tamales, advertising, and late 19th-century imaginative geographies of Mexico

    OpenAIRE

    Monrreal , Sahar

    2008-01-01

    Abstract This article explores how the tamale entered the national market as a mass-produced foodstuff at the end of 19th century. Closely reading advertising images, the article examines how the Armour Packing Company placed their chicken tamale in relation to imaginative geographies of Mexico from this era. Through tracing the symbolic transformations of the tamale from its existence in the street life of the late 19th century US to the nation-wide advertising campaign initiated ...

  1. Temporal analysis and fungicide management strategies to control mango anthracnose epidemics in Guerrero, Mexico

    OpenAIRE

    Monteon Ojeda, Abraham; Mora Aguilera, José Antonio; Villegas Monter, Ángel; Nava Diaz, Cristian; Hernández Castro, Elías; Otero-Colina, Gabriel; Hernández Morales, Javier

    2012-01-01

    The temporal progress of anthracnose (Colletotrichum gloeosporioides) epidemics was studied in mango (Mangifera indica) orchards treated with fungicides from different chemical groups, mode of action, and application sequences in two regions of contrasting climates (sub-humid and dry tropics) in Guerrero, Mexico. Full flowering, initial setting, and 8-15mm Ø fruits were identified as critical stages for infection. Epidemics started 20-26 days after swollen buds, and maximum severity was attai...

  2. Urban planning and habitat III: indications of a necessary reform for Mexico

    OpenAIRE

    Juan Jose Gutierrez Chaparro

    2018-01-01

    Initiatives are being promoted to implement the New Urban Agenda in several cities around the world. This occurs about a year after the New Agenda was adopted in Habitat III. Accelerated urbanization and the aspiration to achieve a sustainable development are the common axes that coincide with Mexico, although our cities continue to grow well beyond any forecasting strategy. The Urban Development Plans in our country follow the same precepts as their predecessors, whose bases correspond to th...

  3. Dioxin Exposure Initiative

    Science.gov (United States)

    The Dioxin Exposure Initiative (DEI) is no longer active. This page contains a summary of the dioxin exposure initiative with illustrations, contact and background information.Originally supported by scientist Matthew Lorber, who retired in Mar 2017.

  4. Magnetic confinement system using charged ammonia targets

    International Nuclear Information System (INIS)

    Porter, G.D.; Bogdanoff, A.

    1979-01-01

    A system is described for guiding charged laser targets to a predetermined focal spot of a laser along generally arbitrary, and especially horizontal, directions which comprises a series of electrostatic sensors which provide inputs to a computer for real time calculation of position, velocity, and direction of the target along an initial injection trajectory

  5. OPORTUNITIES PROGRAM IN MEXICO AND SONORA: IMPACT, EFFICIENCY AND EFFECTIVENESS

    Directory of Open Access Journals (Sweden)

    Irasema Lilian Mancillas-Alvarez

    2015-07-01

    Full Text Available The concept of poverty is based on the monetary approach, which is measured by the method of poverty lines (Foster, Greer and Thoerbecke, 1984; Sen, 1976; while the static microsimulation technique (Bourguignon and Spadaro, 2006 helps quantify the impact of Oportunities in reducing poverty in Mexico and Sonora during the years 2010-2012. The information for this study is obtained from the National Survey of Income and Expenditure Household INEGI (2010, 2012.Lower percentages of poverty were found in Sonora in comparison with the country and no significant impact from the program; the greatest impact was seen in the country since food poverty was reduced (-2.14%, capabilities poverty (- 1.86% and patrimonial poverty (-0.81%. In regards to targeting of the program, in the country there is a slight improvement in efficiency but not in effectiveness and Sonora experienced a significant improvement in efficiency and effectiveness.

  6. Descriptive documentation for New Mexico uranium milling model

    International Nuclear Information System (INIS)

    Bonem, G.; Livevano, R.J.

    1981-01-01

    The New Mexico Uranium Milling Model is a linear programming model. It can demonstrate how cost minimizing management can reduce the costs of milling uranium subject to a series of environmental, resource, and technological constraints. For example, if 15,000 tons were the targeted level of milling output, the model would provide the minimum cost of this production level, given certain levels of environmental, fuel, water, and technological constraints. The model was developed to allow state policymakers to assess the uranium industry from various standpoints. Through the use of the model, state policymakers can determine the effects of air and water discharge standards and limited capital availability on: milling costs of production; uses of electricity, fuel, and water; and levels of air and water emissions. The model covers the following: process technologies which are acid leach and carbonate leach; raw materials mix; air and water discharges; residual treatment process; and plant types

  7. [Prevalence of previously diagnosed diabetes mellitus in Mexico.

    Science.gov (United States)

    Rojas-Martínez, Rosalba; Basto-Abreu, Ana; Aguilar-Salinas, Carlos A; Zárate-Rojas, Emiliano; Villalpando, Salvador; Barrientos-Gutiérrez, Tonatiuh

    2018-01-01

    To compare the prevalence of previously diagnosed diabetes in 2016 with previous national surveys and to describe treatment and its complications. Mexico's national surveys Ensa 2000, Ensanut 2006, 2012 and 2016 were used. For 2016, logistic regression models and measures of central tendency and dispersion were obtained. The prevalence of previously diagnosed diabetes in 2016 was 9.4%. The increase of 2.2% relative to 2012 was not significant and only observed in patients older than 60 years. While preventive measures have increased, the access to medical treatment and lifestyle has not changed. The treatment has been modified, with an increase in insulin and decrease in hypoglycaemic agents. Population aging, lack of screening actions and the increase in diabetes complications will lead to an increase on the burden of disease. Policy measures targeting primary and secondary prevention of diabetes are crucial.

  8. Tall Buildings Initiative

    Science.gov (United States)

    Initiative 2017 TBI Guidelines Version 2.03 Now Available Screen Shot 2017-10-10 at 3.05.10 PM PEER has just initiative to develop design criteria that will ensure safe and usable tall buildings following future earthquakes. Download the primary product of this initiative: Guidelines for Performance-Based Seismic Design

  9. Repetitive output laser system and method using target reflectivity

    International Nuclear Information System (INIS)

    Johnson, R.R.

    1978-01-01

    An improved laser system and method for implosion of a thermonuclear fuel pellet is described in which that portion of a laser pulse reflected by the target pellet is utilized in the laser system to initiate a succeeding target implosion, and in which the energy stored in the laser system to amplify the initial laser pulse, but not completely absorbed thereby, is used to amplify succeeding laser pulses initiated by target refγlection

  10. Does the cerebellum initiate movement?

    Science.gov (United States)

    Thach, W T

    2014-02-01

    Opinion is divided on what the exact function of the cerebellum is. Experiments are summarized that support the following views: (1) the cerebellum is a combiner of multiple movement factors; (2) it contains anatomically fixed permanent focal representation of individual body parts (muscles and segments) and movement modes (e.g., vestibular driven vs. cognitive driven); (3) it contains flexible changing representations/memory of physical properties of the body parts including muscle strength, segment inertia, joint viscosity, and segmental interaction torques (dynamics); (4) it contains mechanisms for learning and storage of the properties in item no. 3 through trial-and-error practice; (5) it provides for linkage of body parts, motor modes, and motordynamics via the parallel fiber system; (6) it combines and integrates the many factors so as to initiate coordinated movements of the many body parts; (7) it is thus enabled to play the unique role of initiating coordinated movements; and (8) this unique causative role is evidenced by the fact that: (a) electrical stimulation of the cerebellum can initiate compound coordinated movements; (b) in naturally initiated compound movements, cerebellar discharge precedes that in downstream target structures such as motor cerebral cortex; and (c) cerebellar ablation abolishes the natural production of compound movements in the awake alert individuals.

  11. [Virtual Campus of Public Health: six years of human resources education in Mexico].

    Science.gov (United States)

    Ramos Herrera, Igor; Alfaro Alfaro, Noé; Fonseca León, Joel; García Sandoval, Cristóbal; González Castañeda, Miguel; López Zermeño, María Del Carmen; Benítez Morales, Ricardo

    2014-11-01

    This paper discusses the gestation process, implementation methodology, and results obtained from the initiative to use e-learning to train human resources for health, six years after the launch of the Virtual Campus of Public Health of the University of Guadalajara (Mexico); the discussion is framed by Pan American Health Organization (PAHO) standards and practices. This is a special report on the work done by the institutional committee of the Virtual Campus in western Mexico to create an Internet portal that follows the guidelines of the strategic model established by Nodo México and PAHO for the Region of the Americas. This Virtual Campus began its activities in 2007, on the basis of the use of free software and institutional collaboration. Since the initial year of implementation of the node, over 500 health professionals have been trained using virtual courses, the node's educational platform, and a repository of virtual learning resources that are interoperable with other repositories in Mexico and the Region of the Americas. The University of Guadalajara Virtual Campus committee has followed the proposed model as much as possible, thereby achieving most of the goals set in the initial work plan, despite a number of administrative challenges and the difficulty of motivating committee members.

  12. Cuba's opening to oil in the Gulf of Mexico: between Mexico's opposition to change and the United States' Blockade

    International Nuclear Information System (INIS)

    De la Vega Navarro, A.

    2007-01-01

    The future of oil for Cuba, Mexico and the United States, which have common maritime borders, lies in the deep waters of the Gulf of Mexico. Cuba faces an energy transition where that source of energy still lays a role, considering the economic and technological structures from the past. Among others, it has opened its territory to international companies, providing them with access to carbon hydride resources in an area of strategic importance, in the midst of a world energy situation where each barrel of oil counts. In addition to economic and technological factors, the Cuban oil opening is explained by the critical situation generated after the termination of the relationship that the country had maintained for several decades with the USSR. The out-come and credibility of such opening should be put into perspective with its ability to build an institutional and regulatory environment likely to attract foreign investments in high risk exploration and production activities. At the same time, Cuba has managed to complete the internal effort conducted with the help of international companies, by engaging in a special relationship with Venezuela, as part of new regional integration programmes and energy cooperation initiated by that country. (author)

  13. Resetting our priorities in environmental health: an example from the South-North partnership in Lake Chapala, Mexico.

    Science.gov (United States)

    Cifuentes, Enrique; Kasten, Felipe Lozano; Trasande, Leonardo; Goldman, Rose H

    2011-08-01

    Lake Chapala is a major source of water for crop irrigation and subsistence fishing for a population of 300,000 people in central Mexico. Economic activities have created increasing pollution and pressure on the whole watershed resources. Previous reports of mercury concentrations detected in fish caught in Lake Chapala have raised concerns about health risks to local families who rely on fish for both their livelihood and traditional diet. Our own data has indicated that 27% of women of childbearing age have elevated hair mercury levels, and multivariable analysis indicated that frequent consumption of carp (i.e., once a week or more) was associated with significantly higher hair mercury concentrations. In this paper we describe a range of environmental health research projects. Our main priorities are to build the necessary capacities to identify sources of water pollution, enhance early detection of environmental hazardous exposures, and deliver feasible health protection measures targeting children and pregnant women. Our projects are led by the Children's Environmental Health Specialty Unit nested in the University of Guadalajara, in collaboration with the Department of Environmental Health of Harvard School of Public Health and Department of Pediatrics of the New York School of Medicine. Our partnership focuses on translation of knowledge, building capacity, advocacy and accountability. Communication will be enhanced among women's advocacy coalitions and the Ministries of Environment and Health. We see this initiative as an important pilot program with potential to be strengthened and replicated regionally and internationally. Published by Elsevier Inc.

  14. Heavy-ion targets

    International Nuclear Information System (INIS)

    Adair, H.L.; Kobisk, E.H.

    1985-01-01

    This chapter examines the characteristics of targets required in heavy-ion accelerator physics experiments. The effects of target parameters on heavy-ion experimental results are reviewed. The target fabrication and characterization techniques used to minimize experimental problems during heavy-ion bombardment are described. Topics considered include target thickness and uniformity, target lifetime, target purity, substrate materials, Doppler shift effects, metal preparations, and target preparation methods

  15. HSIP Emergency Operations Centers (EOC) in New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Emergency Operations Centers (EOC) in New Mexico "The physical location at which the coordination of information and resources to support domestic incident...

  16. All projects related to mexico | Page 5 | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Region: Argentina, South America, Mexico, North and Central America, Peru ... West Indies, Argentina, Chile, Costa Rica, Dominican Republic, Mexico ... which interact in the diffusion, production and use of new and economically useful ...

  17. All projects related to Mexico | Page 4 | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    State and Community Responses to Drug-related Violence in Mexico. Project. Violent conflict related to drug trafficking in Mexico has had a profound impact on the quality of life and health of .... Program: Food, Environment, and Health.

  18. USDA FS Inventoried Roadless Areas in New Mexico, Sept. 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains all National Forest Inventoried Roadless Areas (IRAs) for New Mexico. The IRA data was originally submitted to GSTC by all national forests...

  19. Soil and Water Conservation Districts of New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The New Mexico Soil and Water Conservation District (SWCD) shapefile includes forty-seven boudaries which cover each SWCD throughout the State.

  20. Contexts of offerings and ritual maize in the pictographic record in Central Mexico

    Directory of Open Access Journals (Sweden)

    Natalia Moragas Segura

    2015-01-01

    Full Text Available The objective of this article is an initial enquiry into the evidence and classification of the offerings of maize in Central Mexico from the Classic period to early colonial times. In order to achieve this goal, we will analyse the presence of maize in Central Mexico according to the evidence found in mural paintings and some pictographic codices. Two Mesoamerican cultures will be considered to achieve our analysis: the Teotihuacan and Mexico-Tenochtitlan. Maize was instrumental in the performance of daily rituals and in the diet of these ancient Mesoamerican cultures and the cereal also had sacred connotations in pre-Hispanic, colonial and contemporary narratives. We suggest this by reading the iconographic and symbolic representations of corn in the form of seeds and pods, or as an ingredient in cooked foods which are represented in the mural paintings of Teotihuacan as well as some codices of the post-Classic Nahua tradition. These methodological enquiries reveal evidence of a cultural continuity in Central Mexico as a contrasting perspective on the archaeological and ethno-historical period.