Estudio experimental de la radiación global ultravioleta en San Jose, Costa Rica (ING

Directory of Open Access Journals (Sweden)

Jaime Wright

2016-03-01

Full Text Available Se midieron las radiaciones ultravioleta global y solar global en San José, Costa Rica (latitud: 9°56´, longitud: 84°54´, altitud: 1.172m durante el periodo de octubre 1993 a enero 1995 y se analizaron en función de su variación estacional y de la correlación entre ambas. La dependencia entre la radiación ultravioleta y el índice de claridad del cielo también fue investigada, y se encontró una pobre correlación entre el cociente de la radiación ultravioleta y la radiación solar global (Hv/Hg y el índice de claridad. El coeficiente de correlación entre Hv/Hg y Hg/Ho no fue mayor de 0,25 para cuatro categorías de tipos de cielos, i.e., cielos cubiertos, cielos despejados, así como dos ámbitos intermedios, lo que demuestra que la radiación ultravioleta no solamente está asociada con la claridad del cielo, sino también con otras condiciones de transmisión atmosférica. Un análisis de regresión entre los valores horarios de las radiaciones ultravioleta y global mostró una relación lineal con un coeficiente de determinación mayor del 98%. Esta regresión simple es confiable para la estimación de la radiación ultravioleta a partir de datos de radiación global.

Giant Occipital Intradiploic Epidermoid Cyst.

Science.gov (United States)

Oommen, Arun; Govindan, Jayasree; Peroor, Devan Surendran; Azeez, C Roshan; Rashmi, R; Abdul Jalal, Muhammed Jasim

2018-01-01

Intraparenchymal or intradiploic epidermoid cysts are very rare. Most of these cysts, when present, tend to involve the frontal and temporal lobes, and occasionally, the pineal gland or the brain stem. Here, we report a 45-year-old female, who presented with localized occipital headache and a tender occipital swelling, gradually increasing in size. She was hemodynamically and neurologically stable and did not have any focal neurological deficits. Whole skull and brain imaging revealed a well-demarcated expansile lytic lesion in the right occipital bone, which was hypointense on T1-weighted and hyperintense on both T2-weighted imaging and diffusion-weighted imaging without any contrast enhancement. The patient underwent a right occipital craniotomy and total excision of the intradiploic space occupying lesion. Histopathological examination confirmed the lytic bone lesion over occipital bone as intradiploic epidermoid cyst.

Epidermoid cyst causing hemifacial spasm epidermoid cyst in cerebellopontine angle presenting with hemifacial spasm

Directory of Open Access Journals (Sweden)

Murat Alemdar

2012-01-01

Full Text Available Hemifacial Spasm (HS occurs idiopathically or secondary to the lesions compressing the root exit zone of the facial nerve symptomatically. Symptomatic HS is generally due to vascular compression. We report on a 23-year-old male with right sided HS for a month. Magnetic resonance imaging (MRI of the brain revealed a well-demarcated epidermoid cyst in the right cerebellopontine cistern. It was hypointense on T1-weighted imaging, hyperintense on T2-weighted imaging without contrast enhancement, hyperintense on DWI, and slightly hypointense on ADC relative to the brain. Although it caused shifting of the pons and medulla to the left side and compression of the right cerebellar peduncles and fourth ventricle, the sole symptom of the patient was HS. Clinicians are advised to request MRI/scan for brainstem lesions from the patients with HS. Epidermoid cysts in cerebellopontine cistern may present with HS as the sole symptom.

Gamma knife radiosurgery for cerebellopontine angle epidermoid tumors.

Science.gov (United States)

El-Shehaby, Amr M N; Reda, Wael A; Abdel Karim, Khaled M; Emad Eldin, Reem M; Nabeel, Ahmed M

2017-01-01

Intracranial epidermoid tumors are commonly found in the cerebellopontine angle where they usually present with either trigeminal neuralgia or hemifacial spasm. Radiosurgery for these tumors has rarely been reported. The purpose of this study is to assess the safety and clinical outcome of the treatment of cerebellopontine epidermoid tumors with gamma knife radiosurgery. This is a retrospective study involving 12 patients harboring cerebellopontine angle epidermoid tumors who underwent 15 sessions of gamma knife radiosurgery. Trigeminal pain was present in 8 patients and hemifacial spasm in 3 patients. All cases with trigeminal pain were receiving medication and still uncontrolled. One patient with hemifacial spasm was medically controlled before gamma knife and the other two were not. Two patients had undergone surgical resection prior to gamma knife treatment. The median prescription dose was 11 Gy (10-11 Gy). The tumor volumes ranged from 3.7 to 23.9 cc (median 10.5 cc). The median radiological follow up was 2 years (1-5 years). All tumors were controlled and one tumor shrank. The median clinical follow-up was 5 years. The trigeminal pain improved or disappeared in 5 patients, and of these, 4 cases stopped their medication and one decreased it. The hemifacial spasm resolved in 2 patients who were able to stop their medication. Facial palsy developed in 1 patient and improved with conservative treatment. Transient diplopia was also reported in 2 cases. Gamma knife radiosurgery provides good clinical control for cerebellopontine angle epidermoid tumors.

Malignant Transformation Six Months after Removal of Intracranial Epidermoid Cyst: A Case Report

Directory of Open Access Journals (Sweden)

Fayçal Lakhdar

2011-01-01

Full Text Available Intracranial epidermoid cysts are uncommon benign tumors of developmental origin; malignant transformation of benign epidermoid cysts is rare, and their prognosis remains poor. We report a case of squamous cell carcinoma arising in the cerebellopontine angle. A 52-year-old man presented with left facial paralysis and cerebellar ataxia. He had undergone total removal of a benign epidermoid cyst six months previously. Postoperative magnetic resonance imaging of the brain revealed a heterogeneous and cystic lesion in the left cerebellopontine angle with hydrocephalus. The cyst wall was enhanced by gadolinium. He underwent ventricle-peritoneal shunt and removal again; the histopathological examination revealed a squamous cell carcinoma possibly arising from an underlying epidermoid cyst. This entity is being reported for its rarity. The presence of contrast enhancement at the site of an epidermoid cyst combined with an acute, progressive neurological deficit should alert the neurosurgeon to the possibility of a malignant transformation.

Consecuencias del estrés oxidativo de la piel por radiaciones ultravioleta

OpenAIRE

Alvarez Fontanet, Ernesto

1995-01-01

Se ha avanzado en el conocimiento de la participación de las especies reactivas del oxígeno en la fisiopatología de muchas entidades y fenómenos patológicos. La piel es probablemente uno de los órganos que con mayor frecuencia sufre estrés oxidativo. Las radiaciones ultravioleta constituyen el principal factor generador de estrés oxidativo a este nivel. El fotoestrés oxidativo de la piel por radiaciones ultravioleta está mediado por diferentes mecanismos y favorecido por diversas circunstanci...

Spinal epidermoid cyst with sudden onset of paraplegia

Directory of Open Access Journals (Sweden)

Munshi Anusheel

2009-01-01

Full Text Available Spinal epidermoid cysts, whether congenital or iatrogenic, are relatively uncommon in the spinal cord. When they occur, the typical location is in the subdural, extramedullary space of the lumbo-sacral region. We describe an unusual presentation in a 3-year-old male child which mimicked astrocytoma clinicoradiologically. The child developed sudden onset of inability in walking and weakness of both lower limbs after a fall. There was a dramatic reversal of symptoms after surgery. Histopathology revealed an epidermoid cyst of the spine. On the first follow-up visit at 3 months, the child was asymptomatic.

Differentiated nasosinusal epidermoid carcinoma

International Nuclear Information System (INIS)

Palomo Luna, Jorge; Bestard Hartman, Isel de la Caridad; Fe Soca, Andres Manuel de la

2012-01-01

Two case reports of young patients, who were treated in the Otolaryngology Department from 'Dr. Joaquin Castillo Duany' Teaching Clinical Surgical Hospital in Santiago de Cuba are presented. One of the cases presented nasal obstruction, rhinorrhoea and facial pain, for 7 months; the other one presented an increase of volume in the right ocular globe. In both, the results of the biopsy confirmed the diagnosis of differentiated nasosinusal epidermoid carcinoma

La radiación ultravioleta y su incidencia en la ciudad de Chimbote

OpenAIRE

Uribe Santos, Genaro

2014-01-01

En este artículo se describe la función que cumple la capa de ozono para permitir el desarrollo de la vida en la Tierra, y cómo esta capa se encuentra afectada por el agujero producido a causa de la emisión de gases provocada a su vez por la intensa actividad industrial. Específicamente, se analiza el caso de la ciudad de Chimbote, y se hacen las necesarias recomendaciones para reducir los efectos de los rayos ultravioletas.Palabras clave: radiación ultravioleta, capa de ozono, calentamiento ...

Iatrogenic intraspinal epidermoid tumor: Myelo-CT and MRI diagnosis

Energy Technology Data Exchange (ETDEWEB)

Visciani, A.; Balestrini, M.R.; Solero, C.L.; Savoiardo, M.

1989-07-01

An 11-year-old boy, treated for acute lymphatic leukemia at the age of 2 with intrathecal injections of Methotrexate, presented with a two year history of pain and signs of lumbo-sacral lesion. MRI, myelography and myelo-CT demonstrated an intradural L4-L5 epidermoid tumor which was removed. Iatrogenic implantation of epithelial cells at the age of two with lumbar punctures is most likely. Decline in incidence of lumbar iatrogenic epidermoid cysts, now an exceedingly rare event, is probably related to improved needles for lumbar punctures. (orig.).

Iatrogenic intraspinal epidermoid tumor: Myelo-CT and MRI diagnosis

International Nuclear Information System (INIS)

Visciani, A.; Balestrini, M.R.; Solero, C.L.; Savoiardo, M.

1989-01-01

An 11-year-old boy, treated for acute lymphatic leukemia at the age of 2 with intrathecal injections of Methotrexate, presented with a two year history of pain and signs of lumbo-sacral lesion. MRI, myelography and myelo-CT demonstrated an intradural L4-L5 epidermoid tumor which was removed. Iatrogenic implantation of epithelial cells at the age of two with lumbar punctures is most likely. Decline in incidence of lumbar iatrogenic epidermoid cysts, now an exceedingly rare event, is probably related to improved needles for lumbar punctures. (orig.)

Diffusion tensor mode in imaging of intracranial epidermoid cysts: one step ahead of fractional anisotropy

International Nuclear Information System (INIS)

Jolapara, Milan; Kesavadas, Chandrasekharan; Saini, Jitender; Patro, Satya Narayan; Gupta, Arun Kumar; Kapilamoorthy, Tirur Raman; Bodhey, Narendra; Radhakrishnan, V.V.

2009-01-01

The signal characteristics of an epidermoid on T2-weighted imaging have been attributed to the presence of increased water content within the tumor. In this study, we explore the utility of diffusion tensor imaging (DTI) and diffusion tensor metrics (DTM) in knowing the microstructural anatomy of epidermoid cysts. DTI was performed in ten patients with epidermoid cysts. Directionally averaged mean diffusivity (D av ), exponential diffusion, and DTM-like fractional anisotropy (FA), diffusion tensor mode (mode), linear (CL), planar (CP), and spherical (CS) anisotropy were measured from the tumor as well as from the normal-looking white matter. Epidermoid cysts showed high FA. However, D av and exponential diffusion values did not show any restriction of diffusion. Diffusion tensor mode values were near -1, and CP values were high within the tumor. This suggested preferential diffusion of water molecules along a two-dimensional geometry (plane) in epidermoid cysts, which could be attributed to the parallel-layered arrangement of keratin filaments and flakes within these tumors. Thus, advanced imaging modalities like DTI with DTM can provide information regarding the microstructural anatomy of the epidermoid cysts. (orig.)

Epidermoid Causing Ischemic Stroke in the Brainstem

Directory of Open Access Journals (Sweden)

Raghvendra Ramdasi

2014-01-01

Full Text Available Intracranial tumors may rarely cause stroke. We report an epidermoid cyst causing stroke in a pediatric patient. We have also reviewed the literature and pathogenesis of stroke caused by intracranial tumors.

Efecto de la radiación ultravioleta sobre los ecosistemas acuáticos

OpenAIRE

Zagarese, H.E.; Cravero, W.R.; Villafane, V.; Helbling, W.

1998-01-01

Hasta hace poco tiempo se consideraba que la radiación ultravioleta carecía de importancia como factor ambiental en los ecosistemas acuáticos, ya que se suponía que se absorbía totalmente en los primeros centímetros de la columna de agua. Gracias al desarrollo de mejores instrumentos de medición, hoy se sabe que la penetración de la radiación ultravioleta en el agua es mucho mayor que la estimada anteriormente, y que sus efectos biológicos resultan observables hasta decenas de metros de profu...

An epidermoid cyst of accessory spleen simulating tumors of the tail of pancreas

Directory of Open Access Journals (Sweden)

Amit Kumar Sinha

2015-07-01

Full Text Available An epidermoid cyst of accessory spleen, a rare condition may present as pseudocyst of pancreas and other cystic tumors of the pancreas. This case report along with the review of literature attributes some clinical features and investigative pattern to differentiate between epidermoid cyst of accessory spleen and other cystic tumor of pancreas.

Sublingual epidermoid cyst presenting with distinctive magnetic resonance imaging findings.

Science.gov (United States)

Yoshida, Naohiro; Kodama, Kozue; Iino, Yukiko

2014-06-18

A case of sublingual epidermoid cyst presenting distinctive magnetic resonance imaging (MRI) findings is described. A 39-year-old man presented to our hospital with a three months progressive left submandibular swelling, difficulty moving his tongue, and snoring. Preoperative evaluation with MRI and fine needle aspiration cytology (FNAC) revealed that the heterogeneous cystic lesion contained the squamous cells, which is compatible with ectodermal tissue. The mass was located above the mylohyoid muscle and spread to the pharyngeal space. By considering the size, infection history, patient age, and location, the cyst was completely resected under general anesthesia via cervical approach without any complication. Histopathologically, the cyst wall was lined by stratified squamous epithelium with no skin appendage, suggesting an epidermoid cyst. Ultrasound (US), MRI and FNAC were very useful of the preoperative diagnosis for oral and sublingual lesion. The postoperative course was uneventful and without recurrence after 24 months. This case showed that epidermoid cysts formed the rarely heterogeneous cystic tumor and it underlined usefulness of preoperative diagnosis, such as US, MRI and FNAC for oral and sublingual tumor.

Orbital dermoid and epidermoid cysts: Case study

Directory of Open Access Journals (Sweden)

Veselinović Dragan

2010-01-01

Full Text Available Introduction. Dermoid and epidermoid cysts of the orbit belong to choristomas, tumours that originate from the aberrant primordial tissue. Clinically, they manifest as cystic movable formations mostly localized in the upper temporal quadrant of the orbit. They are described as both superficial and deep formations with most frequently slow intermittent growth. Apart from aesthetic effects, during their growth, dermoid and epidermoid cysts can cause disturbances in the eye motility, and in rare cases, also an optical nerve compression syndrome. Case Outline. In this paper, we described a child with a congenital orbital dermoid cyst localized in the upper-nasal quadrant that was showing signs of a gradual enlargement and progression. The computerized tomography revealed a cyst of 1.5-2.0 cm in size. At the Maxillofacial Surgery Hospital in Niš, the dermoid cyst was extirpated in toto after orbitotomy performed by superciliary approach. Postoperative course was uneventful, without inflammation signs, and after two weeks excellent functional and aesthetic effects were achieved. Conclusion. Before the decision to treat the dermoid and epidermoid cysts operatively, a detailed diagnostic procedure was necessary to be done in order to locate the cyst precisely and determine its size and possible propagation into the surrounding periorbital structures. Apart from cosmetic indications, operative procedures are recommended in the case of cysts with constant progressions, which cause the pressure to the eye lobe, lead to motility disturbances and indirectly compress the optical nerve and branches of the cranial nerves III, IV and VI.

Magnetic resonance imaging and quantitative analysis of contents of epidermoid and dermoid cysts

Energy Technology Data Exchange (ETDEWEB)

Takeshita, Mikihiko; Kubo, Osami; Hiyama, Hirofumi; Tajika, Yasuhiko; Izawa, Masahiro; Kagawa, Mizuo; Takakura, Kintomo; Kobayashi, Naotoshi; Toyoda, Masako [Tokyo Women' s Medical Coll. (Japan)

1994-07-01

The intracapsular cholesterol protein, and calcium contents of epidermoid and dermoid cysts from seven patients were compared with the signal intensities on T[sub 1]-weighted spin-echo magnetic resonance (MR) images. All specimens had a paste-like consistency when resected. Epidermoid and dermoid cysts demonstrated a wide range of cholesterol and calcium contents, and epidermoid cysts were not always rich in cholesterol. Five patients had cysts with lower signal intensity than white matter, which contained more than 18.3 mg/g wet weight of protein. One of these patients had the highest cholesterol content of all seven patients (22.25 mg/g wet weight) and another had the highest calcium content (0.75 mg/g wet weight). Two patients had cysts with higher signal intensity than white matter, with protein contents of lower than 4.3 mg/g wet weight. High protein content (>18.3 mg/g wet weight) may decrease signal intensity on T[sub 1]-weighted MR images, while low protein content (<4.3 mg/g wet weight) may increase signal intensity in epidermoid and dermoid cysts with high viscosity (paste-like consistency) contents. (author).

CISS MR imaging findings of epidermoid tumor : comparison with spin-echo images

Energy Technology Data Exchange (ETDEWEB)

Kim, Yong Woo; Kim, Hak Jin; Choi, Sang Yoel; Heo, Jin Sam; Jung, Hoon Sik; Lee, Suck Hong; Kim, Byung Soo [Pusan National Univ. College of Medicine, Pusan (Korea, Republic of); Lee, Jong Wha [Ulsan Univ. Hospital, Ulsan (Korea, Republic of)

1999-03-01

To evaluate CISS MR imaging findings of epidermoid tumor in comparison with conventional spin-echo images. We studied 6 cases of epidermoid tumor in the subarachnoid space. We used a 1.5T MR unit to obtain CISS images(TR/TE/FA ; 12.3msec/5.9 msec/700) and T1- and T2- weighted spin-echo images. CISS MR imaging findings were evaluated with respect to tumor's signal intensity , contour, and relation with adjacent structures. Conspicuity of the tumor was compared between CISS and spin-echo images. A quantitative analysis was performed by measuring tumor to CSF contrast. In qualitative analysis, three radiologists independently compared CISS image and conventional spin-echo images for visibility of the tumor and graded them into three categories( poor, good, and excellent). Epidermoid tumors were located in the cerebellopontine angle in 4 cases, the prepontine cisstern in 1 case, and the cerebellopontine angle-prepontine cistern in 1 case. The tumors were hyperintense relative to brain parenchyma and hypointense relative to CSF on CISS images, were lobulated, encased adjacent cranial nerve and vessels, and invaginated into brain parenchyma. In qualitative analysis, CISS images showed clear demarcation between tumor and CSF, exact tumor extension, and tumor's relation with cranial nerves and vessels better than conventional spin-echo images. In quantitative analysis, the mean contrast values of tumor to CSF on T1-, T2-weighted images, and CISS images were 0.12, 0.06, and 0.52, respectively. The contrast value for CISS images was significantly higher than that for T1-and T2-weighted images(p<0.05). Epidermoid tumors in the subarachnoid space are better demonstrated on CISS images than on conventional spin-echo images. This special MR sequence can be added as a routine protocol in the diagnosis of subarachnoid epidermoid tumor.

Desenvolvimento de um sistema para irradiação por ultravioleta de biomoléculas

OpenAIRE

Mota, Carlos Daniel Silva

2011-01-01

Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para a obtenção do grau de Mestre em Engenharia Biomédica Foi desenvolvido um sistema destinado ao estudo do efeito da radiação Ultravioleta em amostras biológicas, nomeadamente em estruturas membranares constituídas por lípidos, proteínas, DNA e moléculas intercalantes de DNA potenciadoras do efeito da radiação. O sistema desenvolvido é constituído por uma fonte de luz Ultravioleta, uma lâmpada de...

Case of a spontaneously ruptured epidermoid cyst

Energy Technology Data Exchange (ETDEWEB)

Shiroyama, Y; Saiki, M; Ueda, H; Katayama, S; Mitani, T

1987-02-01

Intracranial fat-containing congenital tumors are characterized by negative absorption values on CT. We hereby report a case of an epidermoid cyst with subarachnoid free fats diagnosed preoperatively by CT. A 21-year-old female was admitted to our hospital because of continuous mild headache and nausea. At the time of admission, the results of her physical and neurological examinations were normal. CT, however, demonstrated multiple subarachnoid low-density spots and a suprasellar low-density area with high-density spots. In addition, there were negative absorption values (-12 -- -77), suggesting free fats. A spontaneously ruptured epidermoid or dermoid cyst was diagnosed on the basis of these findings. At surgery, a suprasellar tumor containing a yellowish, cheese-like material was confirmed. The patient made an uneventful recovery and was discharged 14 days after surgery. There have been several published reports of CT appearances of intracranial fat-containing tumors. However, spontaneously ruptured cases diagnosed by CT are rare. CT was found to be useful for the diagnosis of spontaneously ruptured cases of fat-containing tumors.

Subconjunctival epidermoid cysts in Gorlin-Goltz syndrome.

Science.gov (United States)

De Craene, S; Batteauw, A; Van Lint, M; Claerhout, I; Decock, C

2014-08-01

Epidermoid cysts are common benign cysts which occur particularly on the skin of the face, neck and upper trunk. Subconjunctival location of these cysts is very rare and, until today, only seen in patients with Gorlin-Goltz syndrome. Histopathological examination of these cysts show similarities with odontogenic keratocysts, a typical clinical manifestation of Gorlin-Goltz syndrome.

Rare Locations of Epidermoid Cyst: Case Reports and Review ...

African Journals Online (AJOL)

Hence, we aim at highlighting the differential diagnosis pertaining to the anatomical location. ... Another case in our report was localized in the upper lip. ... Epidermoid cyst, Dermoid cyst , Lower one third of face, Mandibular body, Upper lip.

Experiencias para observar el fenómeno de fluorescencia con luz ultravioleta

Directory of Open Access Journals (Sweden)

Heredia Avalos, S.

2008-09-01

Full Text Available La fluorescencia tiene lugar cuando una sustancia emite luz visible al absorber radiación de una longitud de onda menor, como por ejemplo luz ultravioleta. La diferencia entre la energía absorbida (del fotón ultravioleta y la emitida (del fotón visible se disipa en forma de calor. Se dice que la sustancia posee fluorescenciacuando este proceso es muy rápido; si es más lento se dice que la sustancia posee fosforescencia. A continuación se describen varias experiencias sencillas para poner de manifiesto el fenómeno de fluorescencia. Todas ellas requieren de reactivos y materiales fácilmente accesibles y asequibles y se pueden realizar con alumnos de secundaria o de bachillerato para poner de manifiesto este fenómeno. Además, también se propone una experiencia en la que se observa la reversibilidad de las reacciones químicas ácido-base a través de la fluorescencia.

Evaluation of radiotherapy and chemoradiotherapy for anal canal epidermoid cancer in our center

International Nuclear Information System (INIS)

Obara, Kunihiko; Sahara, Rikisaburo; Yamana, Tetsuro; Okamoto, Kinya; Takahashi, Tomoko; Furukawa, Satomi; Okada, Daisuke; Kaneko, Yasushi; Matsumoto, Atsuo

2008-01-01

The efficacy and safety of radiotherapy (RT) and chemoradiotherapy (CRT) for anal canal epidermoid cancer were evaluated. Twenty-four patients with anal canal epidermoid cancer were treated in our center between 1988 and 2006, consisting of 13 patients treated by RT and 11 by CRT. In these patients, the efficacy and safety of RT and CRT were evaluated in terms of adverse events, 5-year local control rates, 5-year disease-free survival rates, and 5-year survival rates. No grade 3 or higher adverse events were noted in patients receiving RT. In contrast, anorexia, diarrhea, neutropenia, and anemia were observed in 33.3%, 10%, 33.3%, and 10%, respectively, of the patients receiving CRT. The anal preserving rate, 5-year local control rate, 5-year disease-free survival rate, and 5-year survival rate were 66.7%, 73%, 77.5%, and 88.4%, respectively. RT and CRT for anal canal epidermoid cancer should be first-line treatments because of their safety and efficacy. (author)

Surgical treatment of intradiploic epidermoid cyst treated as depression

Directory of Open Access Journals (Sweden)

Živković Nenad

2014-01-01

Full Text Available Introduction. Extradural intradiploic epidermoid cysts are rare, representing less than 0.25% of all primary intracranial tumors. They can be neurologically silent and can only present psychiatric symptoms like depression, cognitive or personality changes. Case Outline. A 68-year-old male with two year long history of depressive mood, lack of motivation, helplessness, hopelessness and poor response to antidepressive drug therapy was described. CT scan showed a well-defined mass in the parietal scalp with destruction of the scull. He underwent intracranial tumor resection. Surgical resection and cranioplasty were performed. Pathology confirmed intradiploic epidermoid cyst. Conclusion. Total removal of these cysts and repeated washing of the cavity with 0.9 % saline may prevent recurrence and aseptic meningitis and may improve mental state of the patient. We also emphasize the need for neuroimaging studies in a patient with atypical changes in mental status, even without neurological signs or symptoms.

Epidermoid carcinoma of the external auditory canal

International Nuclear Information System (INIS)

Alfonso Rodriguez, Javier; Llerena Suarez, Jose Angel; Campis Cruz, Hipolito Amable

2009-01-01

A 43 years-old, urban, male patient assists the consultation of Otolaryngology with a long evolving otorrhea (around two years), receiving several treatments against the external otitis he suffered. With those antecedents and what we found when examining him, we decided to take a sample (biopsy) of the area, diagnosing an epidermoid carcinoma of the left external canal, an infrequent pathology in our settings

A case of a spontaneously ruptured epidermoid cyst

International Nuclear Information System (INIS)

Shiroyama, Yujiro; Saiki, Masahide; Ueda, Hiroyuki; Katayama, Sanao; Mitani, Tetsumi

1987-01-01

Intracranial fat-containing congenital tumors are characterized by negative absorption values on CT. We hereby report a case of an epidermoid cyst with subarachnoid free fats diagnosed preoperatively by CT. A 21-year-old female was admitted to our hospital because of continuous mild headache and nausea. At the time of admission, the results of her physical and neurological examinations were normal. CT, however, demonstrated multiple subarachnoid low-density spots and a suprasellar low-density area with high-density spots. In addition, there were negative absorption values (-12 ∼ -77), suggesting free fats. A spontaneously ruptured epidermoid or dermoid cyst was diagnosed on the basis of these findings. At surgery, a suprasellar tumor containing a yellowish, cheese-like material was confirmed. The patient made an uneventful recovery and was discharged 14 days after surgery. There have been several published reports of CT appearances of intracranial fat-containing tumors. However, spontaneously ruptured cases diagnosed by CT are rare. CT was found to be useful for the diagnosis of spontaneously ruptured cases of fat-containing tumors. (author)

Radiosurgery of epidermoid tumors with gamma knife. Possiblity of radiosurgical nerve decompression

International Nuclear Information System (INIS)

Kida, Yoshihisa; Yoshimoto, Masayuki; Hasegawa, Toshinori; Fujitani, Shigeru

2006-01-01

Long-term results of radiosurgery for epidermoid tumors are reported. There are 7 cases including 2 males and 5 females, ages ranging from 6 to 46 (mean: 33.3 years). At radiosurgery whole tumor was covered in 4 cases and partially covered in 3 cases in attempting to relieve cranial nerve signs like trigeminal neuralgia and facial spasm. The mean maximum and marginal doses were 25.6 Gy and 14.6 Gy respectively. In the mean follow-up of 52.7 months, all the tumors showed good tumor control without any progression and tumor shrinkage has been confirmed in 2 out of the 7 cases. Symptomatic trigeminal neuralgia improved or disappeared in all 4 cases and facial spasm disappeared in one. No neurological deterioration was found in any of the cases after the treatment. In conclusion, it is apparent that epidermoid tumors do respond well to radiosurgery and the accompanying hyperactive dysfunction of cranial nerves is significantly improved by gamma knife treatment with either entire or partial tumor coverage. Therefore the radiosurgical nerve decompression for epidermoid tumor seems to be achieved by gamma-radiosurgery. (author)

A calcified epidermoid cyst within right lateral ventricle: A report of a rare case

Directory of Open Access Journals (Sweden)

Ranjan Kumar Sahoo

2016-01-01

Full Text Available A young patient reported to neurosurgery outdoor department with symptoms of increased intracranial pressure. Noncontrast computed tomography examination showed a single calcified mass within right lateral ventricle with mild hydrocephalus. Contrast-enhanced magnetic resonance imaging revealed nonenhancing single mass within right lateral ventricle with mild hydrocephalus. Intraventricular calcified choroid papilloma/calcified epidermoid were radiological differentials. The mass was excised, removed from the lateral ventricles and found to be calcified epidermoid on gross and microscopic examination, which is rare.

Comparative study of cell alterations in oral lichen planus and epidermoid carcinoma of the mouth mucosa.

Science.gov (United States)

Sousa, Fernando Augusto Cervantes Garcia de; Paradella, Thaís Cachuté; Brandão, Adriana Aigotti Haberbeck; Rosa, Luiz Eduardo Blumer

2009-01-01

Currently, much is discussed regarding the pre-malignant nature of mouth mucosa lichen planus. The present study aims at analyzing the alterations found in the epithelial cells present in the oral cavity lichen planus, comparing them to those found in epidermoid carcinoma. Histological cross-sections of oral lichen planus and epidermoid carcinoma, dyed by hematoxylineosin, were analyzed through light microscopy. The most frequently found alterations in oral lichen planus were: an increase in the nucleus/cytoplasm relation (93.33%), nucleus membrane thickness (86.67%) and bi-nucleus or multinucleous (86.67%). The Student t test (alpha=5%) revealed a statistically significant difference between the average number of cell alterations in oral lichen planus (5.87+/-1.57) and in epidermoid carcinoma (7.60+/-1.81). As to the types of alterations, the chi-squared test also revealed statistically significant differences among the lesions assessed in relation to the following cell alterations: nuclear excess chromatism, atypical mitoses, cellular pleomorphism and abnormal cell differentiation (poral lichen planus, the results obtained in this study show that the alterations present in oral lichen planus differ considerably from those seen in epidermoid carcinoma, thus showing how distinct these two diseases are.

Large and small cells non-keratinizing epidermoid vaginal carcinoma

International Nuclear Information System (INIS)

Maso Anaya, Ofelia; Morales Larramendi, Maria Elena; Diaz Perez, Dolores

2012-01-01

Five case reports of patients who were assisted at the cervix Pathology Department from 'Mariana Grajales Coello' Provincial Gynecological Obstetrical Hospital in Santiago de Cuba due to vaginal bleeding, low abdominal pain, leukorrhea and vaginal injuries are presented. The pathological study confirmed the diagnosis of squamous or epidermoid cells carcinoma

Ruptured splenic epidermoid cyst: case report and imaging appearances

International Nuclear Information System (INIS)

Spencer, N.J.B.; Arthur, R.J.; Stringer, M.D.

1996-01-01

Traumatic rupture of a splenic epidermoid cyst is a rare but recognised cause of ''acute abdomen'' in a child. We describe such a case occurring after very minor trauma, show the influence that imaging had in making an accurate diagnosis, and discuss how this influenced clinical management. (orig.). With 1 fig

Ruptured splenic epidermoid cyst: case report and imaging appearances

Energy Technology Data Exchange (ETDEWEB)

Spencer, N.J.B. [Department of Paediatric Radiology, Clarendon Wing, General Infirmary, Leeds (United Kingdom); Arthur, R.J. [Department of Paediatric Radiology, Clarendon Wing, General Infirmary, Leeds (United Kingdom); Stringer, M.D. [Department of Paediatric Surgery, General Infirmary, Leeds (United Kingdom)

1996-12-01

Traumatic rupture of a splenic epidermoid cyst is a rare but recognised cause of ``acute abdomen`` in a child. We describe such a case occurring after very minor trauma, show the influence that imaging had in making an accurate diagnosis, and discuss how this influenced clinical management. (orig.). With 1 fig.

La radiación ultravioleta y la piel del deportista

Directory of Open Access Journals (Sweden)

José Moncada Jiménez

2003-01-01

Full Text Available En este artículo se presenta una revisión de literatura acerca de la relación entre la radiación solar y las lesiones de la piel. Se sabe que una parte de la población se expone diariamente, y a veces durante muchas horas, a la radiación ultravioleta de los rayos solares. Sin embargo, por desconocimiento o por negligencia, muchas personas sufren de lesiones por la exposición aguda o crónica a los rayos solares. En Costa Rica, las lesiones relacionadas con la exposición al sol son comunes; solamente durante el trienio de 1994 a 1996, el cáncer de piel fue el de mayor incidencia entre las mujeres y el segundo entre los hombres. Se ha llegado a determinar que el riesgo para adquirir cáncer de piel aumenta si se poseen ciertas características fenotípicas, como por ejemplo, piel blanca, cabello color rubio o rojo, y ojos color verde o azul. Aún queda por determinar la posible asociación entre la exposición a los rayos ultravioleta en personas que se exponen diariamente durante largos períodos de tiempo a los rayos solares, como por ejemplo los educadores físicos y los deportistas

Iso-effect tables and therapeutic ratios for epidermoid cancer and normal tissue stroma

International Nuclear Information System (INIS)

Cohen, L.; Creditor, M.

1983-01-01

Available literature on radiation injury to normal tissue stroma and ablation of epidermoid carcinoma was surveyed. Computer programs (RAD3 and RAD1) were then used to derive cell kinetic parameters and generate iso-effect tables for the relevant tissues. The two tables provide a set of limiting doses for tolerance of normal connective tissue (16% risk of injury) and for ablation of epidermoid cancer (16% risk of recurrence) covering a wide range of treatment schedules. Calculating the ratios of normal tissue tolerance to tumor control doses for each treatment scheme provides an array of therapeutic ratios, from which appropriate treatment schemes can be selected

[Epidermoid cyst of the testis difficult to make a preoperative diagnosis on the echoic examination: a case report].

Science.gov (United States)

Yamamoto, Keisuke; Takada, Tsuyoshi; Momohara, Chikahiro; Komori, Kazuhiko; Honda, Masahito; Fujioka, Hideki

2003-04-01

A case of epidermoid cyst of the testis is presented. The patient was a 64-year-old man who complained of a painless mass in the left scrotum. Physical examination revealed a hen-egg sized enlargement of the left scrotal contents. The ultrasonographic appearance did not show a hyperechoic partition, which is called echogenic rim, a characteristic of this tumor on the echoic examination, and was homogeneous, almost similar to that of a normal testis. Because malignant testicular tumors could not be excluded preoperatively, excisional biopsy of the left testis was performed first. Histological diagnosis was an epidermoid cyst of the testis. As the left testis was almost completely occupied by the tumor and no normal testicular tissue was recognized, we performed orchiectomy additionally. Epidermoid cyst of the testis is a rare benign tumor that accounts for about 1 percent of all testicular tumors. It clinically resembles malignant testicular tumors, and orchiectomy is often performed for treatment. About 154 cases of testicular epidermoid cyst have been reported in the Japanese literature and are reviewed briefly here.

Epidermoid cyst of the conus medullaris: atypical MRI and angiographic features

International Nuclear Information System (INIS)

Debray, M.P.; Gaston, A.

1996-01-01

We report a 50-year-old man with an epidermoid cyst of the conus medullaris which showed a nodular gadolinium enhancement on MRI and a blush on angiography. These radiological features are compared with pathological examination. (orig.)

Quantification of diffusion and anisotropy in intracranial epidermoids using diffusion tensor metrics and p: q tensor decomposition.

Science.gov (United States)

Srinivasan, K; Thomas, B; Shah, D; Kannath, S K; Menon, G; Sandhyamani, S; Kesavadas, C; Kapilamoorthy, T R

2016-12-01

To quantitatively evaluate the diffusion tensor metrics p, q, L and fractional anisotropy in intracranial epidermoids in comparison with normal white matter in the splenium of the corpus callosum. This retrospective study included 20 consecutive patients referred to our institute. All patients had a magnetic resonance imaging (MRI) study on a 1.5-Tesla MR system. A spin-echo echo-planar DTI sequence with diffusion gradients along 30 non-collinear directions was performed. The eigen values (λ 1 , λ 2 , λ 3 ) were computed for each voxel and, using p: q tensor decomposition, the DTI metrics p, q and L-values and fractional anositropy (FA) were calculated. The region of interest (ROI) (6 pixels each) was placed within the lesion in all the cases and in the splenium of the corpus callosum. The mean FA in the lesion and splenium were 0.50 and 0.88 respectively, with a statistically significant difference between them (Ptensor decomposition, the mean p-value in the epidermoid was 1.55±0.24 and 1.35±0.20 in the splenium; the mean q-values in the epidermoid was 0.67±0.13 and 1.27±0.17 in the splenium; the differences were statistically significant (P=0.01 and <0.01 respectively). The significant difference between p- and q-values in epidermoids compared with the splenium of callosum was probably due to structural and orientation differences in the keratin flakes in epidermoids and white matter bundles in the callosum. However, no significant statistical difference in L-values was noted (P=0.44). DTI metrics p and q have the potential to quantify the diffusion and anisotropy in various tissues thereby gaining information about their internal architecture. The results also suggest that significant differences of DTI metrics p and q between epidermoid and the splenium of the corpus callosum are due to the difference in structural organization within them. Copyright © 2016. Published by Elsevier Masson SAS.

Gardner syndrome associated with multiple osteomas, intestinal polyposis, and epidermoid cysts

Energy Technology Data Exchange (ETDEWEB)

Koh, Kwang Joon; Park, Ha Na; Kim, Kyoung A [Dept. of Oral and Maxillofacial Radiology, School of Dentistry and Institute of Oral Bioscience, Chonbuk National University, Jeonju (Korea, Republic of)

2016-12-15

Gardner syndrome is known as a variant of familial adenomatous polyposis. This syndrome is characterized by multiple intestinal polyposes, osteomas, and epidermoid cysts. In addition, dental abnormalities include an increased frequency of multiple odontomas, as well as supernumerary and impacted teeth. The authors report the case of a 7-year-old male patient with Gardner syndrome. Radiographic findings revealed multiple osteomas in both sides of the maxilla, multiple diffuse enostoses in both jaws, and a complex odontoma in the left mandibular body. Two years later, multiple epidermoid cysts on the scalp were found. Since this patient was suspected to have Gardner syndrome, the authors recommended gastrointestinal endoscopy to check for intestinal polyposis. Gastrointestinal endoscopic examination revealed multiple polyposes in the upper gastrointestinal tract and fundus of the stomach. As a result, the final diagnosis was Gardner syndrome.

Epidermoid Cyst in the Floor of the Mouth of a 3-Year-Old

Directory of Open Access Journals (Sweden)

Rossana Pascual Dabán

2015-01-01

Full Text Available Epidermoid cysts are a rare entity in the oral cavity and are even less frequent in the floor of the mouth, representing less than 0.01% of all the cases. We present the case of a 3-year-old girl with a growth in the floor of the mouth with 2 months of evolution and without changes since it was discovered by her parents. The lesion was asymptomatic; it did not cause dysphagia, dyspnea, or any other alteration. A CT scan with contrast was done which revealed the location and exact size of the lesion, allowing an intraoral approach for its excision. The histological examination confirmed the clinical speculation of an epidermoid cyst.

LE «SOTTIGLIEZZE DI CERTA DIDATTICA SUPERLATIVA» DELLA GRAMMATICA ELEMENTARE: STORIA (ATTESTATA DEL METODO RAFFORZISTA (1814-1914

Directory of Open Access Journals (Sweden)

Michela Dota

2018-03-01

Full Text Available Il contributo ripercorre la storia e le peculiarità del metodo rafforzista, metodo glottodidattico per l’insegnamento della lettura e della scrittura. Il metodo, nato in Italia nel primo Ottocento, nell’epoca postunitaria era praticato nelle scuole elementari soprattutto dell’Italia meridionale, nonché nelle scuole reggimentali e in alcuni istituti per sordomuti. Le sue fondamenta, aberranti rispetto alla norma ortografica e ortoepica tradizionale, lo resero obiettivo di un tenace ostracismo da parte del Ministero dell’Istruzione pubblica, sostenuto per questa occasione da due tra i più eminenti glottologi dell’epoca: Graziadio Isaia Ascoli e Francesco Lorenzo Pullè. Il metodo finì per estinguersi nel secondo decennio del Novecento.   The history of the “metodo rafforzista” for teaching Italian (1814-1914 This article retraces the history and peculiarities of the “metodo rafforzista”, a language teaching method developed in Italy during the first part of 1800s. In the post-Unitarian period, it was used in elementary schools, especially in Southern Italy, and also in military schools and in some institutes for the Deaf and Dumb. Orthographic and orthoepic models proposed by the “metodo rafforzista” diverged from rules of traditional Italian grammar. The method, supported by Graziadio Isaia Ascoli and Francesco Lorenzo Pullè, two of the most distinguished Italian linguists at that time, was subsequently rejected by the Ministry of Public Education, and it vanished during the second half of 1900s.

Isodense epidermoid cyst in the pineal region

International Nuclear Information System (INIS)

Yamanouchi, Yasuo; Takahara, Nobuhiko; Kawamura, Yasuo; Matsumura, Hiroshi

1985-01-01

A 69-year-old male was admitted complaining of gait disturbances and diplopia, 2.5 years after an episode of serous meningitis. Neurological examination on admission disclosed Parinaud's sign, unsteady gait and dysdiadochokinesis on the left side. A striking finding on the computerized tomography (CT) was the left to right shift of the posterior portion of the third ventricle without visualization of the quadrigeminal and ambient cisterns, which were almost completely occupied by an isodense mass accompanied by high dense flecks and a low dense part. Enhanced CT showed positive enhancement in the vicinity of the pineal calcification. By the suboccipital supracerebellar approach, an encapsulated mass containing brownish yellow fluid was subtotally removed and a histological examination of it revealed epidermoid tissue and hemosiderin deposits in the solid portion. Few reports of isodense epidermoid cysts have so far been found in the literature giving a full explanation for this unusual CT attenuation value. Based on the clinical course and histology of this case, the pathogenesis of the unusual density is discussed along the following lines: The mixture of the low dense factor due to cholesterin and the high dense factor due to prior bleeding is believed to result in the isodense attenuation value in the liquid portion. Also, in the solid part, a microscopically mixed texture of deposited hemosiderin and cholesterin clefts in the inflammatory granulomatous tissue could explain its density on the CT scan. (author)

Balancing the shortcomings of microscope and endoscope: endoscope-assisted technique in microsurgical removal of recurrent epidermoid cysts in the posterior fossa.

Science.gov (United States)

Ebner, F H; Roser, F; Thaher, F; Schittenhelm, J; Tatagiba, M

2010-10-01

We report about endoscope-assisted surgery of epidermoid cysts in the posterior fossa focusing on the application of neuro-endoscopy and the clinical outcome in cases of recurrent epidermoid cysts. 25 consecutively operated patients with an epidermoid cyst in the posterior fossa were retrospectively analysed. Surgeries were performed both with an operating microscope (OPMI Pentero or NC 4, Zeiss Company, Oberkochen, Germany) and endoscopic equipment (4 mm rigid endoscopes with 30° and 70° optics; Karl Storz Company, Tuttlingen, Germany) under continuous intraoperative monitoring. Surgical reports and DVD-recordings were evaluated for identification of adhesion areas and surgical details. 7 (28%) of the 25 patients were recurrences of previously operated epidermoid cysts. Mean time to recurrence was 17 years (8-22 years). In 5 cases the endoscope was used as an adjunctive tool for inspection/endoscope-assisted removal of remnants. The effective time of use of the endoscope was limited to the end stage of the procedure, but was very effective. In a modern operative setting and with the necessary surgical experience recurrent epidermoid cysts may be removed with excellent clinical results. The combined use of microscope and endoscope offers relevant advantages in demanding anatomic situations. © Georg Thieme Verlag KG Stuttgart · New York.

Gigantocellular macrophagal reaction in epidermoid cancer of the lung in patients exposed to preoperative irradiation

International Nuclear Information System (INIS)

Galil-Ogly, G.A.; Kharchenko, V.P.; Poroshin, K.K.; Pereslegin, O.I.; Krylov, L.M.; Ivanov, E.D.

1980-01-01

The histologic and electron microscopic study of frequently occurring gigantocellular macrophagal reaction in the stroma of 83 irradiated epidermoid carcinomas of the lung is carried out. It is found that gigantic multinuclear macrophages take part in the resorption of necrotic and corneous masses as well as in the absorption of viable tumour cells. The presence of gigantocellular macrophagal reaction in the stroma of irradiated tumoUr evidences a more favourable prognosis in patients after the combined treatment of epidermoid lung cancer. Gigantocellular macrophagal reaction should be considered as the manifestation of cell antitumour immunity which makes stronger the tumour irradiation damage

Scienza e conoscenza: sul valore del metodo scientifico

Directory of Open Access Journals (Sweden)

Riccardo Luciano Appolloni

2014-05-01

Full Text Available L’antico problema di riconoscere una forma di conoscenza oggettivae fondata è ancora vivo; in questo scritto cercheremo di capire se la scienza moderna possa essere una forma di conoscenza tale e, quindi, privilegiata. A tal fine ci serviremo del pensiero di alcuni epistemologi e scienziati. In particolare, nel trattare il problema del valore epistemologico del metodo scientifico, non potremo esimerci dal fare i conti con l’anarchismo metodologico di Paul K. Feyerabend, verso il quale l’esito del presente articolo sarà fondamentalmente critico. A partire dai fecondi spunti di questo filosofo, tenteremo dapprima di analizzare i caratteri distintivi della scienza e del suo metodo rispetto ad altre forme di sapere; quindi, cercheremo di individuare alcuni limiti della conoscenza razionale.

Magnetic resonance imaging of epidermoid, including diffusion weighted images and an atypical case

International Nuclear Information System (INIS)

Takahashi, Shoki; Higano, Shuichi; Kurihara, Noriko

1994-01-01

In order to study the role of magnetic resonance imaging (MRI) in diagnosing intracranial epidermoid, we evaluated the MRI findings on five cases with such tumor, all of which were surgically verified. In addition to standard spin-echo (SE) images obtained in all cases, diffusion-weighted images were acquired in two patients. In four patients, the tumor revealed to be almost isointense relative to cerebrospinal fluid (CSF) on both T 1 -and T 2 -weighted images, while it tended to show slightly hyperintense to CSF on proton-density-weighted images; thus, based on the signal intensity on standard SE images the distinction between epidermoid and arachnoid cyst may be difficult. Furthermore, the presence of the tumor which has a tendency to grow in and along the subarachnoid space causing relatively minimal mass effect may be overlooked. Diffusion-weighted images were shown to have advantages in such cases by demonstrating the tumor unequivocally as a mass of high signal, and differentiating it from arachnoid cysts. In the remaining patient, its appearance was atypical, showing bright signal on both T 1 -and T 2 -weighted images. In conclusion free of bone artifacts, multiplanar MRI with additional diffusion-weighted images provides a clear demonstration of epidermoid, and its differentiation from arachnoid cyst, thus obviating the need for CT cisternography. (author)

Dosis de radiación ultravioleta en escolares mexicanos

Directory of Open Access Journals (Sweden)

Castanedo-Cázares Juan Pablo

2003-01-01

Full Text Available OBJETIVO: Determinar la dosis de radiación ultravioleta que reciben los niños y adolescentes durante su asistencia a la escuela primaria, secundaria o preparatoria en la ciudad de San Luis Potosí. MATERIAL Y MÉTODOS: Estudio de cohorte hecho en la ciudad de San Luis Potosí entre mayo de 2001 y abril de 2002. Se evaluaron 80 escolares escogidos al azar de 6 a 19 años de edad, de uno u otro sexo. La dosis se cuantificó durante todo un ciclo escolar mediante el registro del tiempo de exposición solar para cada uno de los alumnos, de modo simultáneo al monitoreo de radiación ultravioleta, para lo cual se utilizaron equipos de radiometría terrestre. Se excluyeron las vacaciones y los fines de semana. Los datos se analizaron en forma univariada y comparativamente, por sexo y meses de exposición; además, se buscó un modelo de regresión para explicar la dosis de exposición solar. RESULTADOS: La dosis promedio ajustada al espectro de eritematógeno acción fue de 16 456 J/m²/año.Hubo diferencias por género: 14 264 J/m²/año/mujeres vs. 18 648 J/m²/año/hombres (Kolmogorov-Smirnof, p=0.003. No hubo diferencias significativas entre grupos, pero sí entre los meses de exposición (Kruskall-Wallis, p=<0.0001. Utilizando la técnica estadística de modelos lineales generalizados, y mediante técnica escalonada y calificación del índice de Akaike se escogió el mejor modelo que explica la dosis de radiación según el mes de exposición, mediante la fórmula 587.20+438.45 (género+500.16(mes-49.65(mes². El resultado muestra mayores dosis de radiación de marzo a septiembre. CONCLUSIONES: Proponemos un marco teórico para la creación de políticas dirigidas a proteger a los alumnos de la sobrexposición solar durante su asistencia a la escuela en México. Se justifica la implantación de medidas preventivas durante al menos el periodo de mayor exposición (marzo a junio, ya que en este lapso se recibe 51% de la dosis anual de radiaci

Magnetic resonance imaging of the intradural prepontine chordoma mimicking an epidermoid cyst: Pathologic correlation

Energy Technology Data Exchange (ETDEWEB)

Cho, Hyoun; Yu, In Kyu; Kim, Seung Min; Kim, Han Kyu [Eulji Univ. Hospital, Daejeon (Korea, Republic of)

2012-08-15

Intracranial chordomas, originating from remnants of the primitive notochord, are extradural tumors arising mostly at the sphenooccipital synchondrosis in the clivus. We present an unusual case of intradural chordoma at the prepontine cistern, with parenchymal compressive invasion to the pons. It was excised subtotally, followed by a second operation due to the increasing remnant tumor size during 8 months. A differential diagnosis for intradural chordoma must be considered when the preoperative MRI features are not consistent with an epidermoid cyst if there are multiple fine enhancing lesions on enhanced magnetic resonance images and no bright signal intensity on diffusion weighted images. This report is concerned with the radiological findings in the intradural chordoma and the differential diagnosis focused on the epidermoid cyst.

Magnetic resonance imaging of the intradural prepontine chordoma mimicking an epidermoid cyst: Pathologic correlation

International Nuclear Information System (INIS)

Cho, Hyoun; Yu, In Kyu; Kim, Seung Min; Kim, Han Kyu

2012-01-01

Intracranial chordomas, originating from remnants of the primitive notochord, are extradural tumors arising mostly at the sphenooccipital synchondrosis in the clivus. We present an unusual case of intradural chordoma at the prepontine cistern, with parenchymal compressive invasion to the pons. It was excised subtotally, followed by a second operation due to the increasing remnant tumor size during 8 months. A differential diagnosis for intradural chordoma must be considered when the preoperative MRI features are not consistent with an epidermoid cyst if there are multiple fine enhancing lesions on enhanced magnetic resonance images and no bright signal intensity on diffusion weighted images. This report is concerned with the radiological findings in the intradural chordoma and the differential diagnosis focused on the epidermoid cyst

Combined regional chemotherapy and radiation therapy in the treatment of epidermoid carcinoma in the oro-facial region

Energy Technology Data Exchange (ETDEWEB)

Danko, J; Satko, I [Komenskeho Univ., Bratislava (Czechoslovakia). Lekarska Fakulta; Durkovsky, J [Institute of Clinical Oncology, Bratislava (Czechoslovakia)

1979-01-01

Treatment was studied of oro-facial epidermoid carcinoma by combined chemo- and radiotherapy and eventual surgery. Cytostatic drugs were applied intraarterially. After a monocytostatic treatment trial with Methotrexate (MTX), a combined cytostatic program was developed alternating two cytostatic drugs, viz., MTX and Bleomycin (BLM). The usefulness of chemotherapy and its inclusion in the treatment of epidermoid carcinoma in the oro-facial region was found justified for combined therapy. The selected intraarterial administration, however, is not suitable for routine application. For this reason, the combination irradiation or surgical therapy with chemotherapy was adopted.

Prognostic significance of s-phase fraction detected by antithymidine antibodies in epidermoid cervix carcinomas

International Nuclear Information System (INIS)

Zamulaeva, Irina A.; Podgorodnichenko, Vladimir K.; Guseva, Ludmila I.; Krikunova, Ludmila I.; Saenko, Alexander S.

1996-01-01

Purpose: To assess the predictive value of pretreatment proliferative activity of epidermoid cervix carcinoma cells with respect to short- and long-term results of radiotherapy. Methods and Materials: The proliferative activity of 25 epidermoid cervix carcinomas was evaluated as the immunofluorescent labelling index (LI) by rabbit antithymidine antibodies reacting specifically with single-stranded DNA of replication forks in S-phase cells. The short-term clinical outcome was estimated at 3-6 months after treatment by visual and palpatory examination. Three-year follow-up data were obtained through hospital charts and correspondence with referring physicians for only 19 patients. Results: There was no statistically significant association between LI and such conventional prognostic factors as clinical stage. The LI value of cervix carcinomas was significantly associated with complete regression at 3-6 months after radiotherapy and 3-year disease-free survival. Complete regression at 3-6 months was observed in 87.5% patients with fast proliferating tumors (LI > 7.0%), and only in 41.2% patients with slowly proliferating tumors (p = 0.03). Probability of 3-year disease-free survival was 85.7% in patients with fast proliferating tumors and 50.0% in those with slowly proliferating tumors (p = 0.05). Conclusions: The immunofluorescent LI of epidermoid cervix carcinoma is able to provide prognostic information on short-term tumor response to radiotherapy and disease-free survival

Epidermoid Cysts – A Wide Spectrum of Clinical Presentation and Successful Treatment by Surgery: A Retrospective 10-Year Analysis and Literature Review

Directory of Open Access Journals (Sweden)

Uwe Wollina

2018-01-01

Full Text Available Epidermoid cysts are common benign lesions of hair-bearing, and less often glabrous skin. They can also occur in oral mucosa and internal organs. In case of cutaneous lesions, an epidermal punctum is a clinical diagnostic hallmark. The clinical presentation is variable leading to some differential diagnoses. Diagnosis of epidermoid cysts needs histopathological confirmation – not only of the potential of malignant transformation. The treatment of choice is surgery. We report a retrospective analysis of 2159 epidermoid cysts treated surgically. Most of the cases can be performed under local anaesthesia. The complication rate of 2.2% is low. To avoid relapses, the cyst wall has to be removed completely. Rare genetic disorders with multiple cysts are Gardner and Lowe syndrome.

Carcinoma epidermoide del margen anal contra calidad de vida

Directory of Open Access Journals (Sweden)

Miguel A Reyes Argudín

Full Text Available La calidad de vida de los pacientes debe tenerse en cuenta. Esta representa el resultado final de la actuación médica desde la perspectiva del paciente. En ocasiones solo nos basamos en este criterio para tomar decisiones terapéuticas ante determinadas enfermedades, como el carcinoma epidermoide de margen anal en estadío terminal. El tratamiento y conducta con fines paliativos tiene como objetivo mejorar la calidad de vida de estas personas. Presentamos el caso de paciente varón de 48 años de edad que acude a consulta por presentar lesión en el ano que no le permitía sentarse y después de realizársele todo el estudio necesario para determinar su diagnóstico definitivo (carcinoma epidermoide de ano evaluarlo y determinar el tratamiento requerido para el grado de la enfermedad, nos percatamos que el tratamiento radical no cambiaba la evolución de su estado y se decide tratamiento paliativo para mejorar la calidad de vida. En ocasiones acuden a consulta pacientes que al culminar su estudio, obtienen el diagnóstico de una enfermedad avanzada y es, a partir de este momento, que nuestro pensamiento médico debe cambiar y encaminar nuestros esfuerzos a mejorar la calidad de vida y no llevarlos a un final tormentoso con el objetivo de revertir la evolución de una enfermedad que no tiene regresión.

Isodense epidermoid cyst in the pineal region. Case report

Energy Technology Data Exchange (ETDEWEB)

Yamanouchi, Yasuo; Takahara, Nobuhiko; Kawamura, Yasuo; Matsumura, Hiroshi

1985-02-01

A 69-year-old male was admitted complaining of gait disturbances and diplopia, 2.5 years after an episode of serous meningitis. Neurological examination on admission disclosed Parinaud's sign, unsteady gait and dysdiadochokinesis on the left side. A striking finding on the computerized tomography (CT) was the left to right shift of the posterior portion of the third ventricle without visualization of the quadrigeminal and ambient cisterns, which were almost completely occupied by an isodense mass accompanied by high dense flecks and a low dense part. Enhanced CT showed positive enhancement in the vicinity of the pineal calcification. By the suboccipital supracerebellar approach, an encapsulated mass containing brownish yellow fluid was subtotally removed and a histological examination of it revealed epidermoid tissue and hemosiderin deposits in the solid portion. Few reports of isodense epidermoid cysts have so far been found in the literature giving a full explanation for this unusual CT attenuation value. Based on the clinical course and histology of this case, the pathogenesis of the unusual density is discussed along the following lines: The mixture of the low dense factor due to cholesterin and the high dense factor due to prior bleeding is believed to result in the isodense attenuation value in the liquid portion. Also, in the solid part, a microscopically mixed texture of deposited hemosiderin and cholesterin clefts in the inflammatory granulomatous tissue could explain its density on the CT scan.

Combination of radiotherapy and cetuximab for patients suffering from of an advanced and non operable epidermoid carcinoma of the ORL sphere: results and side effects; Association de radiotherapie et de cetuximab chez des patients atteints d'un carcinome epidermoide de la sphere ORL evolue non operable: resultats et effets secondaires

Energy Technology Data Exchange (ETDEWEB)

Acevedo, C.; Valette, G.; Bouchekoua, M.; Marianowski, R.; Pradier, O. [CHU Morvan, 29 - Brest (France)

2010-10-15

The authors report a retrospective survey of a set of locally advanced epidermoid carcinomas treated by irradiation and cetuximab. They assessed the response to the treatment, the specific survival, and the global survival as well as the tolerance. The survey is based on 31 men and 5 women suffering from different stage 4 non-metastatic advanced epidermoid carcinomas of the ORL sphere. Short communication

Efeito do filtro de ultravioleta em lentes de contato hidrofílicas de alta hidratação Ultraviolet filter effect on hydrophilic high hydrated contact lenses

Directory of Open Access Journals (Sweden)

Arlindo José Freire Portes

2008-06-01

Full Text Available A exposição à radiação ultravioleta está relacionada ao aparecimento de patologias oculares como ceratites, cataratas, degenerações maculares ou pterígio. Esta radiação está dividida em 3 tipos de acordo com o seu comprimento de onda: Uv-A (320-400nm, Uv-B (290-320nm e Uv-C (100-290nm. A indústria óptica desenvolveu filtros de ultravioleta para lentes intra-oculares, lentes de contato e lentes de óculos. OBJETIVO: Avaliar a eficácia do filtro de ultravioleta em lentes de contato de alta hidratação. MÉTODOS: Seis grupos de lentes de contato de alta hidratação e de marcas diferentes, contendo 3 unidades novas e iguais foram estudadas, observando-se o percentual de transmissão da energia luminosa de 200 a 400 nm através de um espectofotômetro. RESULTADOS: Os 3 grupos que apresentavam filtro de ultravioleta causaram uma queda abrupta na transmissão da radiação ultravioleta de 400 nm até 340 nm, ocorrendo um aumento na transmissão entre 240 a 300 nm até um nível máximo de 45%. Abaixo de 240 nm e entre 300 e 340 nm, houve um completo bloqueio da transmissão da radiação ultravioleta. Os 3 grupos que não apresentavam filtros de ultravioleta causaram uma queda abrupta na transmissão da radiação ultravioleta abaixo de 240 nm, ocorrendo um bloqueio completo de transmissão abaixo de 220 nm. CONCLUSÃO: As lentes de contato sem filtro Uv testadas não bloquearam com eficácia a radiação Uv-A, B ou C, e as com filtro bloquearam quase totalmente a radiação Uv-B e parcialmente a radiação Uv-A e Uv-C.The exposure to ultraviolet radiation is associated with the beginning of ocular pathologies like keratites, cataract, age-related macular degeneration and pterygium. This radiation is divided in 3 bands according to the wave length: Uv-A (320-400, Uv-B (290-320, Uv-C (100-290. The optic industry developed ultraviolet filters to intraocular lenses, contact lenses and spectacle lenses. PURPOSE: The issue of this work is

Concurrent Extravasation Mucocele and Epidermoid Cyst of the Lower Lip: A Case Report

Directory of Open Access Journals (Sweden)

Wen-Chen Wang

2005-10-01

Full Text Available An uncommon case of concurrent extravasation mucocele and epidermoid cyst in the lower lip of a 13-year-old boy is described. To our knowledge, there is no other report of such a concurrence, neither at the same site nor at different locations, involving these two lesions in the oral mucosa.

Perspectives for the treatment of epidermoid oesophageal cancer

International Nuclear Information System (INIS)

Lozac'h, P.

1995-01-01

Prior to the eighties, most patients with a diagnosis of epidermoid oesophageal cancer only received palliative symptomatic care. To date, most all undergo either surgery or medical treatment or both. Late diagnosis due to lack of clinical signs in the early phases of the disease, and perhaps insufficient attempts at identifying patients at risk who could benefit from systematic screening, is still an important problem although the number of diagnosed cases continues to rise (from 104 in 1985 to 151 in 1989 in Finistere in western France). Two different therapeutic attitudes could improve the prognosis: extensive surgery as proposed by the Japanese with dissection of all invaded lymph nodes whatever the localization and a multimodal approach combining radiochemotherapy and surgery. Although outcome can apparently be improved in certain types of oesophageal cancer, the proposal of aggressive extensive dissection could have an effect on respiratory complications and would not necessarily be adapted to the risk involved in western patients. Certain teams have nevertheless taken this route and will soon report their results. In France two phase II trials combining radiotherapy, chemotherapy (cisplatinium) and surgery have reported encouraging results with complete sterilization in 24% of the cases and 50% survival at 18 months. In our own series of 68 patients, we have obtained 41% sterilization and 56,3% survival at 3 years with the multi-modal protocol. The high number on non-responders to chemotherapy emphasizes the importance of maintaining surgical resection whenever possible. The discouraging reports published before 1980 have been contradicted by improvements in outcome achieved over the last decade. Today, all patients with a diagnosis of epidermoid cancer of the oesophagus should benefit from either palliative or curative care based on the latest advances in radiotherapy, chemotherapy and surgery. (author). 10 refs

Estudos sôbre o complemento: II - Análise eletroforética do complemento inativado pelas radiações ultravioleta

Directory of Open Access Journals (Sweden)

F. Rocha Lagôa

1953-12-01

Full Text Available Foi realizada a análise eletroforética de sôros de cobaio, contendo complemento inativado pelas radiações ultravioleta, sendo verificada a existência de modificação na quantidade de albumina e um acréscimo correspondente da zona eletroforética das alfa-globulinas o que confirma a observação anterior de que a fraçãoo do complemento sensível as radiações ultravioleta, e o seu segundo componente (C2.The electrophoretic analysis of sera from guinea pigs was made with complement inactivated by ultraviolet radiations. It was found that the quantity of albumin changed, and an increase of the corresponding electrophoretic area of the globulins-alpha also took place, therefore, confirming the observations made previously that the fraction of the complement destroyed by ultraviolet radiations is its second component (albumin fraction, C2.

Combination of radiotherapy and cetuximab for patients suffering from of an advanced and non operable epidermoid carcinoma of the ORL sphere: results and side effects

International Nuclear Information System (INIS)

Acevedo, C.; Valette, G.; Bouchekoua, M.; Marianowski, R.; Pradier, O.

2010-01-01

The authors report a retrospective survey of a set of locally advanced epidermoid carcinomas treated by irradiation and cetuximab. They assessed the response to the treatment, the specific survival, and the global survival as well as the tolerance. The survey is based on 31 men and 5 women suffering from different stage 4 non-metastatic advanced epidermoid carcinomas of the ORL sphere. Short communication

A calcified epidermoid cyst within right lateral ventricle: A report of a rare case

OpenAIRE

Ranjan Kumar Sahoo; Debahuti Mohapatra; Pradipta Tripathy

2016-01-01

A young patient reported to neurosurgery outdoor department with symptoms of increased intracranial pressure. Noncontrast computed tomography examination showed a single calcified mass within right lateral ventricle with mild hydrocephalus. Contrast-enhanced magnetic resonance imaging revealed nonenhancing single mass within right lateral ventricle with mild hydrocephalus. Intraventricular calcified choroid papilloma/calcified epidermoid were radiological differentials. The mass was excised, ...

Intraparenchymal epidermoid cyst: proper surgical management may lead to satisfactory outcome.

Science.gov (United States)

Zheng, Jian; Wang, Chun; Liu, Fengqiang

2018-03-12

Intraparenchymal epidermoid cysts (IECs) are rare lesions, thus the preoperative diagnosis and proper surgical management are still a challenge. We searched the database at our institution and performed a search of English literature in PubMed and Google Scholar. Keywords used were as follows: "intraparenchymal"; "intracerebral"; "intraaxial"; "epidermoid cyst"; "brainstem"; "cholesteatoma"; "pearly tumor". Only cases that were true intraparenchymally located and contained adequate clinical information were included. Six cases of IECs were recorded at our institution. Total removal was achieved in all the six patients with good outcomes. 29 cases meeting the above criteria were found in the literature. Including ours, a total of 35 patients were analyzed. Females were more frequently affected (F/M ratio, 1.9:1). Most of them were located in the brainstem (42.9%) and temporal lobe (22.9%). While in children, all were located in the brainstem. 45.2% showed subtle peripheral enhancement on Magnetic Resonance Imaging (MRI), and all appeared hyperintense on Diffusion Weighted Imaging (DWI). In the subgroup of cerebral lobes and cerebellums, total resection was achieved in 89.5%, and they all showed good outcomes. While in the subgroup of brainstem, 46.7% (seven cases) underwent total resection and 50% (three cases) of them died postoperatively. MRI with DWI is helpful in the preoperative diagnosis. Total resection should be achieved for the IECs located in cerebral lobes and cerebellums, while subtotal resection is a wise and safe strategy for the IECs located in the brainstem.

Novedoso fotodetector selectivo al ultravioleta basado en dióxido de titanio nanocristalino

Directory of Open Access Journals (Sweden)

H. Wang

2011-01-01

Full Text Available Normal 0 21 false false false MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} Las potencialidades como sensor selectivo de ultravioleta (UV de una celda fotoelectroquímica sellada basada en TiO2 nanocristalino son estudiadas. La componente ultravioleta del espectro solar origina afectaciones en la piel y otras enfermedades; además de provocar limitaciones al desarrollo de los animales y plantas El incremento de la radiación UV exige el uso de sensores para este rango espectral. El TiO2 nanocristalino es un material barato, inocuo y muy estable; actualmente estudiado intensamente debido a sus aplicaciones en celdas solares sensibilizadas. Se describen la obtención y  estructura de los dispositivos y se estudian dos tipos de fotodetectores con diferentes estructuras de capas. Para ello se analizan parámetros característicos del fotodetector tales como la sensibilidad espectral, la eficiencia cuántica externa, la dependencia de la fotocorriente vs la intensidad luminosa y la curva volt-ampérica en oscuridad e iluminada. Los valores de sensibilidad obtenidos y la dependencia lineal de la fotocorriente con la intensidad incidente, unidos a su bajo costo, confieren buenas perspectivas para el desarrollo de este tipo de sensor.

Desinfecção de água de chuva por radiação ultravioleta Disinfection of rainwater by ultraviolet radiation

Directory of Open Access Journals (Sweden)

Elisabeth Wisbeck

2011-12-01

Full Text Available O objetivo deste trabalho foi avaliar o tratamento de água de chuva, de duas regiões industriais de Joinville (SC, por radiação ultravioleta. O reator operou em processo contínuo, de modo que cada partícula permanecesse sob radiação por 60 segundos. As amostras de água foram analisadas em termos de coliformes totais, coliformes termotolerantes e bactérias heterotróficas antes do tratamento por ultravioleta, após o tratamento e após tratadas e armazenadas por 24, 48 e 72 horas. Verificou-se a eficiência da desinfecção de água de chuva direta e de telhado por radiação ultravioleta com a inativação de 100% dos coliformes totais e dos coliformes termotolerantes e o não recrescimento desses micro-organismos em amostras tratadas e estocados por até 72 horas, no entanto, bactérias heterotróficas persistiram e foram identificadas após 24, 48 e 72 horas ao tratamento.The objective of this study was to evaluate the treatment of rainwater in two industrial regions in Joinville (SC, Brazil by ultraviolet radiation. The reactor was operating in continuous process with each particle remaining under radiation for 60 seconds. The samples were evaluated in terms of total coliforms, fecal coliform and heterotrophic bacteria prior to ultraviolet treatment, after treatment and further treated and stored for 24, 48 and 72 hours. The efficiency of disinfection of direct rainwater and that collected from roofing by ultraviolet radiation was verified with 100% inactivation of total coliforms and fecal coliform and these microorganisms did not reappear in samples treated and stored for up to 72 hours, however, heterotrophic bacteria persisted and were identified after 24, 48 and 72 hours of treatment.

Subtotal resection and omentoplasty of the epidermoid splenic cyst: a case report

Science.gov (United States)

Spahija, Gazmend S; Hashani, Shemsedin I; Osmani, Eshref A; Hoxha, Sejdullah A; Hamza, Astrit H; Gashi-Luci, Lumturije H

2009-01-01

Introduction Nonparasitic splenic cysts are uncommon clinical entity and because of it, there is no information regarding their optimal surgical treatment. Case presentation A 41-years-old female with incidentally diagnosed nonparasitic splenic cyst which initially was asymptomatic. After two years of follow up, the patient underwent surgery; subtotal cystectomy and omentoplasty as an additional procedure. Postoperative course was uneventful. Conclusion Short and mid term results showed that near total cystectomy with omentoplasty was a safe successful procedure for treatment of epidermoid splenic cyst. PMID:19829799

MODELO CINÉTICO PARA LA INACTIVACIÓN DE MICROORGANISMOS EN DESINFECCIÓN DEL AGUA CON LUZ ULTRAVIOLETA Y ENERGÍA SOLAR

Directory of Open Access Journals (Sweden)

Antonio Sarmiento Sera

2011-02-01

Full Text Available En el reporte se expone un modelo para el proceso cinético de inactivación de microorganismos en unsistema de desinfección del agua que utiliza luz ultravioleta y energía solar fotovoltaica. Se presentanlos resultados de dos experimentos y el comportamiento del modelo propuesto para la caracterizacióncinética del proceso. El sistema está analizado como una posibilidad para la desinfección del aguacon luz ultravioleta en tanques o recipientes domésticos, donde no es factible el uso de sistemas aflujo.  In the report, a model is exposed for the kinetic process of microorganisms inactivation in awater disinfecting system that uses ultraviolet light and photovoltaic solar energy. The resultsof two experiments and the behavior of the proposed model for the kinetic characterization ofthe process are presented. The system is analyzed as a possibility for the water disinfecting withultraviolet light in tanks or domestic recipients, where it is not feasible the use of flow systems.

Induction of apoptosis and antiproliferative activity of naringenin in human epidermoid carcinoma cell through ROS generation and cell cycle arrest.

Directory of Open Access Journals (Sweden)

Md Sultan Ahamad

Full Text Available A natural predominant flavanone naringenin, especially abundant in citrus fruits, has a wide range of pharmacological activities. The search for antiproliferative agents that reduce skin carcinoma is a task of great importance. The objective of this study was to analyze the anti-proliferative and apoptotic mechanism of naringenin using MTT assay, DNA fragmentation, nuclear condensation, change in mitochondrial membrane potential, cell cycle kinetics and caspase-3 as biomarkers and to investigate the ability to induce reactive oxygen species (ROS initiating apoptotic cascade in human epidermoid carcinoma A431 cells. Results showed that naringenin exposure significantly reduced the cell viability of A431 cells (p<0.01 with a concomitant increase in nuclear condensation and DNA fragmentation in a dose dependent manner. The intracellular ROS generation assay showed statistically significant (p<0.001 dose-related increment in ROS production for naringenin. It also caused naringenin-mediated epidermoid carcinoma apoptosis by inducing mitochondrial depolarization. Cell cycle study showed that naringenin induced cell cycle arrest in G0/G1 phase of cell cycle and caspase-3 analysis revealed a dose dependent increment in caspase-3 activity which led to cell apoptosis. This study confirms the efficacy of naringenin that lead to cell death in epidermoid carcinoma cells via inducing ROS generation, mitochondrial depolarization, nuclear condensation, DNA fragmentation, cell cycle arrest in G0/G1 phase and caspase-3 activation.

FGF2 mediates DNA repair in epidermoid carcinoma cells exposed to ionizing radiation

International Nuclear Information System (INIS)

Marie, Melanie; Hafner, Sophie; Moratille, Sandra; Vaigot, Pierre; Rigaud, Odile; Martin, Michele T.; Mine, Solene

2012-01-01

Fibroblast growth factor 2 (FGF2) is a well-known survival factor. However, its role in DNA repair is poorly documented. The present study was designed to investigate in epidermoid carcinoma cells the potential role of FGF2 in DNA repair. The side population (SP) with cancer stem cell-like properties and the main population (MP) were isolated from human A431 squamous carcinoma cells. Radiation-induced DNA damage and repair were assessed using the alkaline comet assay. FGF2 expression was quantified by enzyme linked immunosorbent assay (ELISA). SP cells exhibited rapid repair of radiation induced DNA damage and a high constitutive level of nuclear FGF2. Blocking FGF2 signaling abrogated the rapid DNA repair. In contrast, in MP cells, a slower repair of damage was associated with low basal expression of FGF2. Moreover, the addition of exogenous FGF2 accelerated DNA repair in MP cells. When irradiated, SP cells secreted FGF2, whereas MP cells did not. FGF2 was found to mediate DNA repair in epidermoid carcinoma cells. We postulate that carcinoma stem cells would be intrinsically primed to rapidly repair DNA damage by a high constitutive level of nuclear FGF2. In contrast, the main population with a low FGF2 content exhibits a lower repair rate which can be increased by exogenous FGF2. (authors)

Multimodality approach to surgical management of locally advanced epidermoid carcinoma of the anorectum

International Nuclear Information System (INIS)

Wanebo, H.J.; Futrell, W.; Constable, W.

1981-01-01

Seven patients (five female, two male) had locally advanced epidermoid carcinoma of the anal canal. Three patients had recurrent or persistent disease previously treated and four had advanced primary cancer. Five patients had groin node metastasis. The treatment protocol consisted of chemotherapy with continuous 5-day infusion of 5-fluorouracil, 750 mg/m2, and mitomycin C, 15 mg/m2, by bolus injection and radiation 3000 rads. All patients received one or two cycles of chemotherapy pre-operatively and four (not previously irradiated) received radiation. Tumor regression greater than 50% occurred in five patients, minor regression (25-50%) occurred in one patient and one patient showed no regression (on chemotherapy alone). All patients had total resection of all gross tumor with microscopic clear margins and five had groin dissection. One patient had no residual cancer in specimen and one patient had a microscopic focus only. Four of five patients had residual nodal metastases at groin dissection. Currently three patients are free of disease at 24, 24, and 26 months. Two patients died with disease at 6 months and 34 months, and two patients died of other causes while still free of disease, at 4 and 5 months after resection. Multimodality therapy of locally advanced epidermoid cancer of anal canal can provide effective control and palliation of many of these tumors and, in some, possibly effect cure

Estudio numerico y experimental del proceso de soldeo MIG sobre la aleacion 6063--T5 utilizando el metodo de Taguchi

Science.gov (United States)

Meseguer Valdenebro, Jose Luis

improvement on mechanical properties in aluminum metal joint. Los procesos de soldadura por arco electrico representan unas de las tecnicas mas utilizadas en los procesos de fabricacion de componentes mecanicos en la industria moderna. Los procesos de soldeo por arco se han adaptado a las necesidades actuales, haciendose un modo de fabricacion flexible y versatil. Los resultados obtenidos numericamente en el proceso de soldadura son validados experimentalmente. Los principales metodos numericos mas empleados en la actualidad son tres, metodo por diferencias finitas, metodos por elementos finitos y metodo por volumenes finitos. El metodo numerico mas empleado para el modelado de uniones soldadas, es el metodo por elementos finitos, debido a que presenta una buena adaptacion a las condiciones geometricas y de contorno ademas de que existe una diversidad de programas comerciales que utilizan el metodo por elementos finitos como base de calculo. Este trabajo de investigacion presenta un estudio experimental de una union soldada mediante el proceso MIG de la aleacion de aluminio 6063-T5. El metodo numerico se valida experimentalmente aplicando el metodo de los elementos finitos con el programa de calculo ANSYS. Los resultados experimentales obtenidos son: las curvas de enfriamiento, el tiempo critico de enfriamiento t4/3, geometria del cordon, microdurezas obtenidas en la union soldada, zona afectada termicamente y metal base, dilucion del proceso, areas criticas intersecadas entre las curvas de enfriamiento y la curva TTP. Los resultados numericos son: las curvas del ciclo termico, que representan tanto el calentamiento hasta alcanzar la temperatura maxima y un posterior enfriamiento. Se calculan el tiempo critico de enfriamiento t4/3, el rendimiento termico y se representa la geometria del cordon obtenida experimentalmente. La zona afectada termicamente se obtiene diferenciando las zonas que se encuentran a diferentes temperaturas, las areas criticas intersecadas entre las

The place of radiotherapy in muco-epidermoid carcinomas of salivary glands in child

International Nuclear Information System (INIS)

Thariat, J.; Temam, S.; Orbach, D.; Nicollas, R.; Penicaud, M.; Toussaint, B.; Makeieff, M.; Laprie, A.; Castillo, L.; Vedrin, P.

2011-01-01

As muco-epidermoid carcinomas are the most frequent tumours of salivary glands for child, the authors report the study of the role of radiotherapy. This study is based on a survey performed in 34 paediatric departments. The authors analyse the age and gender, the use of irradiation, the tumour location, the tumour grade and size, the use of surgery and of radiotherapy, and survival. Radiotherapy is beneficial for high grade tumours, but cannot be recommended for low and intermediate grades. Short communication

Interest of the serous dosage of HER-2/neu, EGFr, VEGF, IL6 and Ac anti-P53 among patients damaged by an esophagus epidermoid carcinoma, type epidermoid carcinoma whom treatment was an exclusive chemoradiotherapy

International Nuclear Information System (INIS)

Metges, J.P.; Le Tallec-Jestin, V.; Mahlaire, J.P.; Pradier, O.; Guenet, D.; Volant, A.; Codet, J.P.

2006-01-01

The serous concentrations of EGFr and HER2/neu seem to have a potential interest in the framework of the assumption of esophagus epidermoid carcinomas. A next step consists in comparing the serous value of these markers with their tissue expression on biopsies. A prospective study in parallel of a therapeutic trial is starting up to validate these results on a bigger number of patients. (N.C.)

Novel Tc-99m labeled ELR-containing 6-mer peptides for tumor imaging in epidermoid carcinoma xenografts model. A pilot study

International Nuclear Information System (INIS)

Kim, Dae-Weung; Kim, Woo-Hyoung; Kim, Myoung-Hyoun; Kim, Chang-Guhn

2013-01-01

ELR-containing peptides targeting CXCR2 could be the excellent candidate for targeting ligand of molecular tumor imaging. In this study, we had developed two ELR-containing 6-mer peptides and evaluated the diagnostic performance of Tc-99m labeled 6-mer peptides as a molecular imaging agent in murine models bearing KB epidermoid carcinoma. Peptides were synthesized using Fmoc solid phase peptide synthesis. Radiolabeling efficiency with Tc-99m was evaluated using instant thin-layer chromatography. In KB epidermoid cancer-bearing mice, gamma images had acquired and tumor-to-muscle uptake ratio was calculated. Competition and biodistribution studies had performed. Two 6-mer peptides, ELR-ECG and ECG-ELR were successfully synthesized. After radiolabeling procedures with Tc-99m, the complex Tc-99m ELR-ECG and Tc-99m ECG-ELR were prepared in high yield. In the gamma camera imaging of murine model, Tc-99m ELR-ECG was substantially accumulated in the subcutaneously engrafted tumor and tumor uptake had been suppressed by the free ELR co-injection. However, Tc-99m ECG-ELR was minimally accumulated in the tumor. Two ELR-containing 6-mer peptides, ELR-ECG and ECG-ELR, were developed as a molecular imaging agent to target CXCR2 of epidermoid carcinoma. Tc-99m ELR-ECG had showed significant uptake in tumor and it was good candidate for a tumor imaging. (author)

Interest of the serous dosage of HER-2/neu, EGFr, VEGF, IL6 and Ac anti-P53 among patients damaged by an esophagus epidermoid carcinoma, type epidermoid carcinoma whom treatment was an exclusive chemoradiotherapy; Interet du dosage serique de HER-2/neu, EGFr, VEGF, IL6 et Ac anti-P53 chez des patients atteints d'un carcinome epidermoide de l'oesophage de type carcinome epidermoide dont le traitement etait une chimioradiotherapie exclusive

Energy Technology Data Exchange (ETDEWEB)

Metges, J.P.; Le Tallec-Jestin, V.; Mahlaire, J.P.; Pradier, O. [Departement de Cancerologie, 29 - Brest (France); Guenet, D.; Volant, A. [Service d' anatomopathologie, 29 - Brest (France); Codet, J.P. [Service de Medecine Nucleaire, 29 - Brest (France)

2006-11-15

The serous concentrations of EGFr and HER2/neu seem to have a potential interest in the framework of the assumption of esophagus epidermoid carcinomas. A next step consists in comparing the serous value of these markers with their tissue expression on biopsies. A prospective study in parallel of a therapeutic trial is starting up to validate these results on a bigger number of patients. (N.C.)

Review of photodynamic therapy with 5-methyl aminolevulinate in actinic keratosis, epidermoid carcinoma and basal cell carcinoma

International Nuclear Information System (INIS)

Fallas Moya, Said

2013-01-01

A bibliographic review was conduced on the use of 5-methyl aminolevulinate in dermatology, specifically in the treatment of actinic keratosis, epidermoid carcinoma and basal cell carcinoma. The basic fundamentals of photodynamic therapy are described. The preparation and method of use of photodynamic therapy with 5-methyl aminolevulinate (MAL-PDT) are detailed. The clinical studies that were realized with photodynamic therapy for the treatment of actinic keratosis, epidermoid carcinoma and basal cell carcinoma are mentioned. Different photo-inducible agents and other current therapeutic options of first-line are compared. The MAL-PDT has have the advantage of to present less side effects and the same have been more tolerable than liquid nitrogen and 5 fluorouracil. The MAL-PDT has been considered as an effective option for the treatment of Bowen's disease. Invasive epidermoid carcinoma has existed without evidence to support the routine use of this therapeutic. For superficial basal cell carcinoma, the MAL-PDT has presented a high cure rate and transient and manageable side effects in extensive and multiple lesions. The MAL-PDT has been an effective and safe treatment in patients with basal cell carcinoma, for those with less depth of 2mm. The MAL-PDT could play an important role in the field of prevention with immunosuppressed patients, particularly, those that have required transplant and its immunosuppression has been pharmacological. The use or not of the MAL-PDT, should be evaluated individually for each patient and to have suitable characteristics for each disease that was cited in this review. The photodynamic therapy with 5-methyl aminolevulinate has been a therapeutic modality of considerable economy, however, it should be evaluated in the context of number of inquiries and side effects that have offered other therapeutic modalities [es

Osservazioni sul principio di legalità come idea e come metodo nell’esperienza giuridica della Chiesa

Directory of Open Access Journals (Sweden)

Beatrice Serra

2012-10-01

SOMMARIO: 1. Introduzione - 2. – La struttura essenziale del concetto di legalità e la sua realizzazione radicale nel diritto della Chiesa. - 3. L’idea di legalità come “regola che sta prima” nel ius commune e la sua coesistenza con un approccio empirico, essenzialmente giurisprudenziale e dottrinale, di costruzione del diritto. Il principio di legalità come metodo di produzione del diritto nel pensiero giuridico moderno- 4. Il legame storico-concettuale fra il principio di legalità e i Codici moderni - 5. Il Codex iuris canonici del 1917 e il principio di legalità come metodo di costruzione del ius ecclesiae in funzione della certezza del diritto - 6. (segueUlteriori riflessi della prima codificazione canonica sul principio di legalità.:

APLICACIÓN DE LA ESPECTROFOTOMETRÍA ULTRAVIOLETA PARA DETERMINAR EL OXÍGENO DISUELTO EN AGUA POR EL MÉTODO WINKLER

OpenAIRE

Ramírez T., Gustavo

1992-01-01

Se utilizó la espectrofotometría ultravioleta en reemplazo de la titulación convencional con tiosulfato de sodio para determinar el oxígeno disuelto en aguas naturales por el método Winkler. La determinación del oxígeno en aguas de diferente salinidad (Río Manzanares, Ciénaga Grande y Bahía de Santa Marta) no mostró diferencias estadísticas significativas (p

Efeitos da aplicação do L.A.S.E.R. HeNe e do ultravioleta B no vitiligo

Directory of Open Access Journals (Sweden)

Ana Carolina Brandt de Macedo

Full Text Available INTRODUÇÃO: O vitiligo é uma doença crônica despigmentante da pele, ocasionada pela perda funcional dos melanócitos da epiderme. Este estudo teve como objetivo comparar os efeitos da aplicação do L.A.S.E.R. HeNe e do ultravioleta B em pacientes com vitiligo. MÉTODO: Foram selecionados 22 pacientes (11 mulheres e 11 homens, com idade entre 12 e 60 anos (31,68 ± 16,29. Os pacientes foram distribuídos aleatoriamente, de acordo com a ordem de comparecimento no serviço e foram divididos randomicamente em dois grupos: o grupo A (n = 12, submetido à aplicação do L.A.S.E.R. HeNe, para o qual a técnica utilizada foi a pontual com aproximadamente 3 cm de distância entre cada ponto, perpendicularmente à pele, e o grupo B (n = 10, exposto ao Ultravioleta B, aplicado de forma perpendicular com 10 cm de afastamento da pele do paciente. Para mensuração da área tratada, utilizou-se o programa AUTOCAD 2002, no qual foi delimitada a borda da mácula em fotos tiradas no início e no fim do tratamento. RESULTADOS: Inicialmente, no grupo A, a área era de 4,87 cm² ± 3,70 e, após a aplicação, foi de 4,15 cm² ± 2,89, com diferença média de 0,72 cm² (1,89. No grupo B, verificou-se que antes da aplicação a média era de 5,36 cm² ± 6,36 e, a após a aplicação, foi de 4,43 cm² ± 5,17, com diferença média de 0,92 cm² ± 1,29. CONCLUSÃO: Ambos os aparelhos obtiveram resultados significativos na redução da mácula, com maior redução no grupo da ultravioleta.

Exposición a fuentes de radiación ultravioleta en los lugares y situaciones más insospechadas

OpenAIRE

Aguilera, J.

2015-01-01

Antecedentes: Existen determinadas situaciones en las que es común la exposición a fuentes de radiación ultravioleta artificial que normalmente pasa de forma asintomática para la mayoría de las personas. No obstante, existen determinadas fotodermatosis que dan lugar al paciente un grado de sensibildad muy alto a dicha exposición con respuestas anómalas a corto y medio plazo. El conocimiento tanto de la calidad espectral y la intensidad de la radiación a la que el paciente puede estar potencia...

Microscale adaptation of the potentiometric method with ion-selective electrode for the quantification of fluoride; Adaptacion a microescala del metodo potenciometrico con electrodo ion selectivo para la cuantificacion de fluoruro

Energy Technology Data Exchange (ETDEWEB)

Guevara Ruiz, Paulina; Ortiz Perez, Maria Deogracias [Laboratorio de Bioquimica, Facultad de de Medicina, Universidad Autonoma de San Luis Potosi, San Luis Potosi, San Luis Potosi, (Mexico)]. E-mail: mdortiz@uaslp.mx

2009-05-15

Similarly to other countries, ground water from Mexico is naturally polluted by fluoride. The main effects of fluoride at typical ground water concentrations are dental fluorosis, neurological deficits and reproductive disorders. In order to verify that the fluoride concentration is within the allowed guideline in Mexico (NOM 127 and 201), it is important to monitor fluoride levels in water and commercial beverages. The aim of this work is to develop a modification of the standard potentiometric method for fluoride determination in water, in order to reduce costs and amount of potentially toxic waste substances. Both methods were validated, the standard potentiometric method with the ion selective electrode and the microscale modification proposed in this paper. The methods were compared using statistic tests and graphics, followed by the comparison of 125 samples of commercial bottled water sold in the city of San Luis Potosi. Optimal results were obtained for the validation of both methods, and the microscale modification showed statistically identical results to those obtained with the standard method in all samples of bottled water. The microscale modification is a good alternative for fluoride assessment in water and beverages, and it represents a 95 % reduction of costs and chemical waste. [Spanish] En varios paises, incluido Mexico se presenta una contaminacion natural con fluoruro en agua subterranea; los principales efectos en la salud observados en poblacion expuesta a concentraciones mayores al valor permisible (que en Mexico es de 1.5 mg/L) son la fluorosis dental y esqueletica, asi como dano reproductivo y neurologico. En varios estados de la republica Mexicana, este problema es aun desconocido, de ahi la necesidad de evaluar las concentraciones de fluoruro en agua de consumo en varias comunidades. Asi, el objetivo de este trabajo es desarrollar un metodo a microescala para la determinacion de fluoruro en agua, que al reducir la cantidad de reactivo y

LA RADIACIÓN ULTRAVIOLETA EN EL DOCENTE DE EDUCACIÓN FÍSICA: PREVENCIÓN DE RIESGOS LABORALES

OpenAIRE

José Rizo Agüera; Ángel Bernal Valero; Ester Hernández García

2008-01-01

Los docentes de Educación Física representan un grupo de población que se expone crónicamente a la radiación solar. "La importancia de la radiación ultravioleta (RUV) en la inducción de cáncer cutáneo fue demostrada directamente en 1959 por Blum" (Serra y Tribó, 1994, p. 329). Existen pocas investigaciones descriptivas del cuidado de la piel de los educadores físicos. El presente artículo tiene por objeto la reflexión de los riesgos que de la exposición solar se derivan en la labor docente, t...

Granulomatosis de Wegener Semejando Cáncer Epidermoide de Nasofaringe y Metástasis Pulmonares.

Directory of Open Access Journals (Sweden)

Gustavo Adolfo Martín Small

2011-01-01

Full Text Available La granulomatosis de Wegener (GW es una enfermedad idiopática, con posible componente autoinmune, que aparece generalmente en la quinta década de vida, caracterizándose por lesiones granulomatosas necrotizantes y vasculitis en vías aéreas y riñón. Paciente femenino de 54 años, quien desde Noviembre del 2008, presenta rinorrea, prurito y eritema en borde nasal inferior izquierdo, recibe antibióticos sin mejoría de los síntomas. En las radiografías torácicas, se observan dos radiopacidades redondeadas, de 4 cm de diámetro, sugestivas de lesiones tumorales en ambos campos pulmonares. La biopsia reporta cáncer epidermoide de alto grado, sospechándose primario en nasofaringe. Es remitida, por deterioro de condiciones, al Servicio de Neumonología del Hospital Universitario de Caracas el 18/03/2009, presentando disnea, tos productiva, placas purpúricas dolorosas en manos y pies, hipoacusia, hiperpigmentación del paladar duro, leucoplaquias y lesiones costrosas en lengua, insuficiencia renal (creatinina en 6,11 mg/dL y trombocitopenia. En TAC de tórax, se evidencian tumores mayores de 5 cm de diámetro, algunos con bordes bien definidos y otros mal delimitados con broncograma aéreo. Diagnostico definitivo de GW por serología. La GW con su afectación sistémica puede simular otras entidades como neoplasias de cabeza y cuello con metástasis pulmonares. Cuando las manifestaciones sistémicas son floridas debe sospecharse GW como diagnóstico diferencial. Palabras claves: Wegener, Granulomatosis, Vasculitis, Cáncer epidermoide.

DOLOČITEV POVRŠINSKE NAPETOSTI Z METODO KAPILARNEGA DVIGA DVOFAZNIH SISTEMOV

OpenAIRE

Kravanja, Gregor

2014-01-01

Namen magistrske naloge je bil postavitev merilne naprave in razvoj nove metode merjenja površinske napetosti s kapilarnim dvigom dvofaznih sistemov v okolici kritične točke. Za pridobitev natančnih in primerljivih meritev je bilo potrebno poznati natančni notranji premer tankih kapilar. Določili smo ga z metodo laserskega tipanja na nemški koordinatni merilni napravi ZEISS tipa UMC-850 s pomočjo merilne programske opreme CALYPSO 5.1.4. Za merjenje ravnotežne višine smo uporabili računalniški...

Herpetic keratitis after corneal collagen cross-linking with riboflavin and ultraviolet-A for progressive keratoconus.

Science.gov (United States)

Yuksel, Nilay; Bilgihan, Kamil; Hondur, Ahmet M

2011-12-01

To describe a case of herpetic keratitis after corneal collagen cross-linking (CXL) with riboflavin and ultraviolet-A for progressive keratoconus. A 31-year-old woman with rapidly progressive keratoconus in the left eye was treated with CXL. Four days postoperatively, a dendritic ulcer developed in the treated eye. The diagnosis was confirmed with polymerase chain reaction analysis of the corneal swab for herpes simplex. The patient had no prior history of herpetic eye disease or cold sores. The keratitis resolved in 10 days with treatment. At 1 month, the visual acuity was stable, but a mild superficial opacity was noted. Herpetic keratitis can be induced by CXL even in patients with no history of previous herpetic eye disease. Early diagnosis and proper treatment can facilitate successful management of this rare but important complication.

Tumores dermóides e epidermóides intra-espinhas Intraspinal epidermoid and dermoid tumours

Directory of Open Access Journals (Sweden)

Oscar Fontenelle Filho

1971-03-01

Full Text Available São relatados dois casos de tumores epidermóides e um de tumor dermóide, todos intrarraquianos. Este último era de localização epidural ao nível da coluna torácica (caso 3; os dois tumores epidermóides situavam-se na coluna tóraco-lombar (caso 1 e lombar (caso 2, respectivamente, sendo o primeiro intramedular e o segundo intradural. Em dois casos (casos 2 e 3 os tumores associavam-se a fístula dérmica congênita. Um paciente (caso 3 foi operado aos dois meses de idade; a descoberta do tumor deveu-se à realização da raquimanometria que revelou bloqueio, apesar do paciente não apresentar qualquer sinal neurológico de compressão medular. Os autores são de opinião que, em presença de fístula dérmica congênita ao nível da coluna vertebral, principalmente quando localizada acima do segmento lombosacro, deve-se sempre suspeitar da possibilidade do tumor epidermóide ou dermóide intrarraquiano, mesmo na ausência de sinais neurológicos. A combinação de sintomas neurológicos de longa duração, a evidência radiológica de erosão e alargamento do canal raquiano e a história de fístula dérmica congênita proporcionaram o diagnóstico pré-operatório correto no caso 2.Two cases of epidermoids and one case of dermoid intraspinal tumours are reported. The last case was located at thoracic level (T7 (case 3 and was epidural in localization. The two epidermoids tumours were located at the thoracic-lumbar (case 1 and lumbar (case 2 level, respectively; the first was intramedullary and the second subdural in localization. In two (cases 2 and 3 there was associated communicating pilonidal sinuses. One of the patients (case 3 was operated within the second month of age. The early discovery of the tumour in this patient was made through a lumbar raquimanometry that disclosed a complete subarachnoid block. In spite of this the patient did not presented any neurological symptoms. The authors are of opinion that in presence of a

AUMENTO DEL ÍNDICE SOLAR ULTRAVIOLETA CON LA ALTURA SOLAR ULTRAVIOLET INDEX INCREASE WITH ALTITUDE

Directory of Open Access Journals (Sweden)

Miguel Rivas A

2008-09-01

Full Text Available En este trabajo se presentan los resultados obtenidos al realizar comparaciones entre mediciones experimentales de Índice solar ultravioleta (IUV obtenido a partir de datos experimentales y también de resultados teóricos proveniente del cálculo del IUV mediante el modelo TUV (modelo ultravioleta troposféricol. En especial se destacan los aumentos de la irradianza solar ultravioleta B (UVB 280-320 nm que se reciben a nivel del suelo debido a los aumentos de la altitud del lugar sobre el nivel del mar (efecto altitudinal. Los cálculos mediante el modelo TUV se realizaron en un período comprendido entre los años 1996-2003, introduciendo los parámetros de los lugares geográficos en que se hicieron las mediciones experimentales. Dado que una de las variables importantes de la que depende el IUV es la altitud sobre el nivel del mar y considerando que la zona norte de Chile es un lugar con características especiales para realizar este tipo de estudios, es que se han realizado experimentos para medir la irradianza solar UVB entre 0-3.200 m de altura, y a partir de estos datos se ha obtenido el IUV. La importancia de estos resultados radica en el hecho que a partir de ellos se pueden cuantificar el incremento de la irradianza UVB por cada 1.000 m de altitud sobre el nivel del mar. Un número creciente de personas se desplazan continuamente entre el nivel del mar y altitudes cercanas a los 5.000 m, debido a trabajos relacionados con: minería, turismo, transporte. En todos estos casos estas personas reciben importantes incrementos de irradianza solar UV, que pueden afectar gravemente su salud si no se informan de los riesgos para que puedan tomar precauciones.In this work we present results from ultraviolet solar index (IUV comparisons between values obtained from experimental measurements, with theoretical results obtained from tropospherical ultraviolet model (TUV. It is important to emphasise the observed increase in solar ultraviolet B (UVB

LA RADIACIÓN ULTRAVIOLETA EN EL DOCENTE DE EDUCACIÓN FÍSICA: PREVENCIÓN DE RIESGOS LABORALES

Directory of Open Access Journals (Sweden)

José Rizo Agüera

2008-01-01

Full Text Available Los docentes de Educación Física representan un grupo de población que se expone crónicamente a la radiación solar. "La importancia de la radiación ultravioleta (RUV en la inducción de cáncer cutáneo fue demostrada directamente en 1959 por Blum" (Serra y Tribó, 1994, p. 329. Existen pocas investigaciones descriptivas del cuidado de la piel de los educadores físicos. El presente artículo tiene por objeto la reflexión de los riesgos que de la exposición solar se derivan en la labor docente, tomando conciencia de los mismos y estableciendo una serie de recomendaciones preventivas.

Contrasting effects of ultraviolet-A and ultraviolet B exposure on induction of contact sensitivity in human skin

DEFF Research Database (Denmark)

Skov, Lone; Hansen, Henrik; Barker, J. N.

1997-01-01

Ultraviolet-B (UVB), in addition to direct effects on DNA, induces immunological changes in the skin that predispose to the development of skin cancer. Whether ultraviolet-A (UVA) induces similar changes is unknown. This effect can be investigated in humans in vivo using epicutaneous antigens...... as a model of tumour antigens. Volunteers (n = 46) were randomly assigned to received no sensitization, sensitization with the allergen diphenylcyclopropenone (DPCP) on non-UV-exposed normal skin, or sensitization with DPCP on skin exposed to three minimal erythema doses (MED) of either UVA or UVB radiation...... the immunization rate compared with sensitization on non-irradiated skin (P UVA radiation did not result in a decreased immunization rate compared with non-irradiated skin. These results indicate that in humans erythemagenic...

Observaciones del disco solar y de una protuberancia quiescente en radiación ultravioleta

Science.gov (United States)

Cirigliano, D.; Vial, J.-C.; Rovira, M.

Observaciones del disco solar y de una protuberancia quiescente en el rango de longitudes de onda ultravioleta fueron obtenidas con el instrumento CDS (Coronal Diagnostic Spectrograph) y SUMER (Solar Ultraviolet Measurements of emitted radiation) a bordo de la sonda SOHO. El propósito es investigar las velocidades macroscópicas de varias especies metálicas que se observan tanto en el disco solar como en el plasma de las protuberancias. Para calcular las velocidades del disco solar aplicamos una técnica mixta para modelar la distribución de estructuras en UV en el Sol quieto. Las velocidades macroscópicas en las protuberancias se calcularon a partir de los corrimientos Doppler en cada línea espectral y luego se tomaron las del disco solar como referencia. Obtuvimos valores absolutos para las velocidades macroscópicas entre 5 y 40 km/seg. También detectamos comportamientos diferentes en las velocidades de las protuberancias en el centro con respecto a los bordes.

Re-irradiation in stereotactic conditions and cetuximab for local relapses of epidermoid carcinoma of head and neck; Reirradiation en conditions stereotaxiques et cetuximab pour des recidives locales de carcinome epidermoide de la tete et du cou

Energy Technology Data Exchange (ETDEWEB)

Vasseur, F.; Comet, B.; Faivre-Pierret, M.; Coche-Dequeant, B.; Degardin, M.; Lefebvre, J.L.; Lacornerie, T.; Lartigau, E. [Departement universitaire de radiotherapie, centre Oscar Lambret, 59 - Lille (France); Universite Lille-2, 59 (France)

2010-10-15

The authors report a work aimed at assessing the feasibility and toxicity of a re-irradiation treatment in stereotactic conditions using CyberKnife and cetuximab in the case of local relapses of epidermoid cancers of the ORL sphere. Thirty three patients have been submitted to this treatment between June 2007 and April 2009. Although six patients died by six months, this treatment seems to be a good alternative, and presents an acceptable short-term toxicity. Further studies are needed to compare this technique to other therapeutic techniques, and to assess the risk of long term complications. Short communication

Vulvar Epidermoid Cyst and Type 2 Radical Genital Mutilation

Directory of Open Access Journals (Sweden)

Ozer Birge

2015-01-01

Full Text Available About 100 million women are estimated to be circumcised globally. Various rates of complications have been encountered, especially after circumcision, such as bleeding, infection, shock, menstrual irregularity, difficulty in urination or common urinary tract infections, inguinal pain, difficulty in sexual intercourse, and genital circumcision scar especially at the vulvar region, and cystic or solid character mass in short and long term. Furthermore, the maternal-fetal morbidity and mortality increase due to bleeding and fistula, which develop after prolonged labor, travail, and difficult labors. Our aim in this paper was to discuss a 42-year-old multiparous female case who had undergone type 2 radical genital mutilation (circumcision when she was 7 years of age, along with the literature, which has been evaluated for the gradually growing mass at the left inguinal canal region in the last 10 years and diagnosed as epidermoid inclusion cyst developing secondary to postcircumcision surgical ground trauma, since there was no other case found in the literature search that had been circumcised at such an early age and developing after circumcision at such advanced age, and, therefore, this is suggested to be the first case on this subject.

Acquired Encephalocele With Hydrocephalus and Pineal Region Epidermoid Cyst.

Science.gov (United States)

Toktaş, Zafer Orkun; Yilmaz, Baran; Ekşi, Murat Şakir; Bayoumi, Ahmed B; Akakin, Akin; Yener, Yasin; Demir, Mustafa Kemal; Kiliç, Türker

2016-07-01

A combination of trauma and a missed inflammatory response (nasal operation) concomitant with hydrocephalus and tumor in secondary encephalocele has not been described in the English literature yet. A 38-year-old man was admitted to the clinic with rhinorrhea that started 3 months ago. In his medical history, nothing abnormal was present except a nasal operation performed 1 year ago. Brain magnetic resonance imaging depicted left frontal encephalocele concomitant with obstructive hydrocephalus caused by an epidermoid cyst originated from the pineal region. A 2-staged surgery was planned. In the first stage, a ventriculoperitoneal shunt insertion was conveyed successfully. In the second-stage surgery, the herniated brain tissue was excised, and the frontal sinus was cleansed with serum saline combined with antibiotic. The bony defect and the dura defect were repaired. The patient's presenting complaint recovered fully, and he was discharged to home in a well condition. Acquired encephalocele is a rare entity. In case of rhinorrhea and encephalocele, even in the presence of prior history of nasal surgery, intracranial evaluation should be conveyed to exclude the presence of hydrocephalus and/or tumor. The cranial defect should be repaired to prevent future infections and brain tissue damage.

Radiación ultravioleta y lesiones melanocíticas. Implicación en prevención y diagnóstico precoz de melanoma.

OpenAIRE

Carrera Álvarez, Cristina

2013-01-01

La radiación ultravioleta (RUV) juega un papel fundamental en el desarrollo de lesiones melanocíticas adquiridas, benignas y malignas, siendo al igual que la presencia de nevus, los principales factores de riesgo para el desarrollo de melanoma. Asimismo, las nuevas clasificaciones moleculares del melanoma han suscitado un creciente interés por el papel etiopatogénico de la RUV. A pesar de los revolucionarios avances en terapéutica, la prevención continúa siendo la pieza clave de la lucha con...

La radiación ultravioleta en el docente de Educación Física: Prevención de Riesgos Laborales

OpenAIRE

Rizo Agüera, José; Bernal Valero, Ángel; Hernández García, Ester

2008-01-01

Los docentes de Educación Física representan un grupo de población que se expone crónicamente a la radiación solar. “La importancia de la radiación ultravioleta (RUV) en la inducción de cáncer cutáneo fue demostrada directamente en 1959 por Blum” (Serra y Tribó, 1994, p. 329). Existen pocas investigaciones descriptivas del cuidado de la piel de los educadores físicos. El presente artículo tiene por objeto la reflexión de los riesgos que de la exposición solar se derivan en la labor docente...

Estudio espectroscópico de la radiación electromagnética ultravioleta, visible e infrarroja cercana sobre la obra pictórica.

OpenAIRE

D'ANTONI, PABLO LUIS

2013-01-01

La Tesis "Estudio Espectroscópico de la Radiación Electromagnética, Ultravioleta Visible e Infrarroja cercana sobre la Obra Pictórica" de Pablo D'Antoni desarrolla un método no invasivo para caracterizar, medir y predecir daños a los pigmentos y aglutinantes en obras pictóricas, probablemente por la radiación electromagnética (REM). Usando 3 formas de Espectroscopia: 1) Irradiancia, 2) FORS(Espectroscopía de Reflectancia (y Absorbancia) con Fibra Optica, se analizan los efectos producidos por...

Torque calculation in the induction motor with the finite element method; Calculo del par en el motor de induccion con el metodo del elemento finito

Energy Technology Data Exchange (ETDEWEB)

Castillo Diaz, Ramon

2002-06-15

In this work the method of the finite element is applied to the bi-dimensional analysis of the induction motor in operation in steady state, excited by sine sources of laminar currents and sine sources of voltage. The analysis is focused mainly in the calculation of the electromagnetic torque. The topics of electromagnetic theory are covered and in an idealized model of the induction motor, analytically and numerically with the method of the finite element, in the variant method of Galerkin, the vectorial potential and the torque are calculated. The results obtained with the analytical and numerical methods are compared. Three formulations are developed to calculate the torque with the method of the finite element, using triangular elements of first order, based in the equation of force of Lorentz, the Maxwell tensor and the principle of the virtual work. Finally, a motor of induction of real characteristics is simulated, assuming it is connected to a three-phase voltage source. In this motor it is analyzed the convergence and the evolution in the results obtained of the torque with different discretions, and the torque-velocity performance curve is calculated. [Spanish] En este trabajo se aplica el metodo del elemento finito al analisis bidimensional del motor de induccion en operacion en estado estable, excitado por fuentes de corriente laminar senoidales y fuentes de voltaje senoidales. El analisis se enfoca principalmente en el calculo del par electromagnetico. Se tratan los topicos de teoria electromagnetica involucrados y en un modelo idealizado del motor de induccion, se calculan analitica y numericamente con el metodo del elemento finito, en la variante metodo de Galerkin, el potencial vectorial y el par. Se comparan resultados obtenidos con los metodos analiticos y numericos. Se desarrollan tres formulaciones para calcular el par con el metodo del elemento finito, utilizando elementos triangulares de primer orden, basadas en la ecuacion de fuerza de

Polimorfismo do fungo simbionte de formigas cortadeiras submetido à luz ultravioleta Polymorphism of the cutting ants symbiotic fungus submitted to ultraviolet light

Directory of Open Access Journals (Sweden)

Regina da Silva Borba

2007-10-01

Full Text Available O presente trabalho teve por objetivo verificar o efeito de diferentes períodos de luz ultravioleta sobre a similaridade genética do fungo simbionte de formigas cortadeiras pertencentes às espécies Acromyrmex ambiguus, Acromyrmex crassispinus e Acromyrmex lundi, através da técnica AFLP. Os fungos foram inoculados em meio de cultura Pagnocca e mantidos em câmaras climatizadas à temperatura de 25 + 1°C e escotofase de 24h, por um período de 15 dias. Posteriormente, foram expostos à luz ultravioleta por períodos de: 0, 5, 10, 15, 20, 25 e 30 minutos. Aos 45 dias após o tratamento, foi realizada a extração do DNA e padronização, realizando-se as reações de PCR por meio de 24 combinações de primers AFLP, das quais quatro foram selecionadas por apresentarem maior polimorfismo e consistência. Os dados moleculares foram transformados em matriz binária e analisados pelo programa estatístico NTSYS v. 2.1. As quatro combinações de primers utilizadas geraram 152 bandas polimórficas. As populações de fungos originárias de diferentes espécies de Acromyrmex apresentaram uma similaridade genética média de 37%, sendo que a indução de mutação através da luz ultravioleta permitiu obter isolados mais dissimilares.The present research was aimed at verifing the effect of different periods of ultraviolet light on the development of the symbiont fungus of leaf cutting ants belonging to the species Acromyrmex ambiguus, Acromyrmex crassispinus and Acromyrmex lundi, through the AFLP technique. The fungus were inoculated in Pagnocca's medium and maintained in climatized cameras at 25 + 1°C and 24 hours of darkness, for a period of 15 days. After that, they were exposed to ultraviolet light for 0, 5, 10, 15, 20, 25, and 30 minutes. At 45 days after the treatment, the extraction and standardization of DNA was performed. PCR reactions were tested using 24 AFLP primer combinations, from which four were selected because they presented

Correlacion entre metodos de analisis de Zn disponible en cuatro ordenes de suelos de Costa Rica

Directory of Open Access Journals (Sweden)

Eloy Molina

2001-01-01

Full Text Available Se realizo una comparación entre métodos analisis del Zn disponible en 4 ordenes de sue- Analytilos de Costa Rica (Ultisoles, Vertisoles, Andisoles Inceptisoles, 25 de c/u, utilizando las siguientes soluciones extractoras: Olsen Modificado, Meh- lich 3, Morgan Modificado, DTPA y HC1. Las cantidades de Zn extrafdas dependieron de la natu- raleza qufmica de la solucion extractora. El HCl presento los contenidos mas altos de Zn en los chasuelos, excepto en Vertisoles. Las soluciones que hicontienen el agente quelante EDTA (Olsen Modi- ficado y Mehlich`3, extrajeron niveles interme- Modidios de Zn, en tanto que los metodos que contie- Den el quelato DTPA (Morgan Modificado y DT - PA, obtuvieron los valores mas bajos. Las corre- laciones de Zn extrafble entre los 5 metodos fue- signifirOD significativas en la mayona de los casos, tanto nivel de orden de suelos como en el conjunto de indivilos 100 suelos analizados. Los coeficientes de co- rrelacion mas altos, se presentaron entre Mehlich Morgan Modificado y DTPA. Las correlaciones Modifueron consistentes en los 4 ordenes, 10 que indica que estas soluciones poseen un amplio margen de adaptacion a diferentes tipos de suelo, siendo una caractenstica ventajosa para la selección de un metodo de analisis. El Olsen Modificado fue mas slighteficiente para la extraccion de Zn en suelos de pH ligeramente acido 0 neutro (Vertisoles e Inceptiso- les, que en suelos acidos (Ultisoles y Andisoles. EI HCI extrajo cantidades muy aItas de Zn que Moraparentementestan relacionadas con formas no disponibles para lag plantas. Se concluye que lag soluciones Mehlich 3, Morgan Modificado y DT - PA son semejantes en la forma de extraer Zn dispo- Dible, y podrian seT una altemativa para sustituir el metoda tradicional de Olsen Modificado utilizado en Costa Rica. Sin embargo,la eficiencia de ellas no puede seT establecida sino a traves de log estudios de correlacion contra rendimiento en invernadero y campo.

EVALUACIÓN DE LA ACTIVIDAD ANTIOXIDANTE DE ACEITES ESENCIALES EN EMULSIONES DEGRADADAS POR RADIACIÓN ULTRAVIOLETA

Directory of Open Access Journals (Sweden)

Geovanna Tafur

2008-03-01

Full Text Available En este trabajo se evaluaron las actividades antioxidantes in vitro de los aceites esenciales de Origanum vulgare L., Rosmarinusofficinalis L. y Coriandrum sativum L., en emulsiones de agua en aceite (Ag/Ac y aceite en agua (Ac/Ag, sometidas al deterioro oxidativo por medio de la radiación ultravioleta A-visible (UVAVIS.En la emulsión de Ag/Ac (margarina, el aceite esencial de orégano presentó actividad antioxidante superior a la del cilantro y el romero, e incluso a la de la vitamina E, en concentraciones de 1, 10 y 20 g/kg. Se estableció además, que la acción antioxidante in vitro de los aceitesesenciales de orégano y cilantro aumentaba con su concentración en la margarina.Por último, el aceite esencial de orégano presentó una acción protectora más baja en la emulsión de Ac/Ag.

Proteção à radiação ultravioleta: recursos disponíveis na atualidade em fotoproteção Ultraviolet radiation protection: current available resources in photoprotection

Directory of Open Access Journals (Sweden)

Tatiana Santana Balogh

2011-08-01

Full Text Available A radiação ultravioleta pode provocar danos ao DNA, imunossupressão, alterações químicas e histológicas na epiderme, envelhecimento precoce, cataratas e carcinogênese, dentre outras deteriorações. A fotoproteção previne estes e outros efeitos danosos da radiação ultravioleta. Protetores solares, vestimentas, acessórios adequados e exposição segura ao sol são ferramentas essenciais da fotoproteção. Neste artigo, são apresentadas e discutidas as principais formas de fotoproteção, incluindo os protetores solares com filtros inorgânicos e orgânicos, a avaliação da eficácia dos mesmos e atualizações envolvendo o temaUltraviolet radiation can damage the DNA, cause immunosuppression, chemical and histological alterations in the epidermis, early photoaging, cataracts and carcinogenesis, among others. Photoprotection prevents these and other harmful effects of ultraviolet radiation. Sunscreens, protective clothing, proper accessories and safe sun exposure are essential photoprotection tools. The main forms of photoprotection are presented and discussed in this article, including sunscreens containing organic and inorganic filters, the assessment of their efficacy and current developments on the topic

Method to allow the estimation of heat transfer coefficients in solar stills; Metodo para determinar coeficientes locales de transferencia de calor en destiladores solares

Energy Technology Data Exchange (ETDEWEB)

Rubio Cerda, Eduardo; Porta Gandara, Miguel A [CIBNOR, Mexico D.F (Mexico); Fernandez Zayas, Jose Luis [UNAM Mexico, D.F. (Mexico)

2000-07-01

This work reports an experimental method that allows to estimate the heat transfer coefficients in the neighborhood of walls or flat plates subject to convective transport phenomena. This method can be applied to a great variety of thermal systems since it is based on the knowledge of the border condition for the temperature at the surface of the plate, and the temperature profile that characterize the dimensionless coefficient of heat transfer in the fluid, according to its definition given by the Nusselt number. The approach of this work are the foundations of the method and the system that has been developed to apply it, that incorporates automatic acquisition equipment for continuos monitoring of the information and elements to control the parameters of interest. In addition, the experimental cavities on which the method will be evaluated are discussed, considering two different scales, as well as experiments in cavities filled with air, and with a mixture of air and steam water, as is the case for solar distillation. [Spanish] En este trabajo se presenta un metodo que permite determinar de manera experimental coeficientes de transferencia de calor por conveccion. Este metodo puede ser aplicado a una gran variedad de sistemas termicos ya que se fundamenta en el conocimiento de la condicion de frontera para la temperatura en la superficie de la placa, y del perfil de temperaturas que caracteriza el coeficiente adimensional de transferencia de calor en el fluido, de acuerdo a la definicion de este, dada por el numero de Nusselt. El trabajo que aqui se reporta esta enfocado a la fundamentacion del metodo y al equipamiento que se ha desarrollado para instrumentarlo, que incorpora equipos automaticos de adquisicion continua de informacion y elementos de control para los parametros de interes. Se presentan ademas, las cavidades experimentales sobre las que sera evaluado el metodo, que considera dos escalas diferentes, asi como experimentos en cavidades llenas de aire

Method of identifying the friction of rotors using the wavelet transform; Metodo para identificar el rozamiento de rotores utilizado la transformada wavelet

Energy Technology Data Exchange (ETDEWEB)

Jauregui Correa, Juan Carlos; Rubio Cerda, Eduardo; Gonzalez Brambila, Oscar [CIATEQ, A.C., Queretaro (Mexico)

2007-11-15

The modern processes of signal analysis that measure mechanical vibrations are based on the fast transform of Fourier (FFT), nevertheless, this method is not able to identify transient phenomena nor of nonlinear nature. Although many efforts have been made to try to identify these phenomena in the frequency spectra, it is not possible to correlate the spectra with the physical characteristics of this type of phenomena. Within these phenomena on the rubbing of a rotor against the housing or trunnion of a bearing, this phenomenon has a nonlinear behavior, as it is demonstrated in this paper. In the first part a method based on the of signal analysis type wavelets is presented and how this technique can be used to predict transient and nonlinear phenomena. Once defined the method, its application in the identification of the friction of rotors is demonstrated. With this, one demonstrates that the method presented in this paper allows to also identifying in real time the rubbing phenomenon and also that it can be used as an of analysis technique in the preventive maintenance systems. [Spanish] Los procesos modernos de analisis de senales que miden vibraciones mecanicas se basan en la transformada rapida de Fourier (FFT por sus siglas en ingles), sin embargo, este metodo no es capaz de identificar fenomenos transitorios ni de naturaleza no lineal. A pesar de que se han hecho muchos esfuerzos para tratar de identificar estos fenomenos en los espectros de frecuencia, no es posible correlacionar el espectro con las caracteristicas fisicas de este tipo de fenomenos. Dentro de estos fenomenos sobre el rozamiento de un rotor contra la carcasa o munon de una chumacera, este fenomeno tiene un comportamiento no lineal, como se demuestra en este trabajo. En la primera parte se presenta un metodo basado en el analisis de senales tipo wavelets y como esta tecnica puede utilizarse para predecir fenomenos transitorios y no lineales. Una vez definido el metodo, se demuestra su

Treatment of epidermoid tumors with gamma knife radiosurgery: Case series.

Science.gov (United States)

Vasquez, Javier A Jacobo; Fonnegra, Julio R; Diez, Juan C; Fonnegra, Andres

2016-01-01

Epidermoid tumors (ETs) are benign lesions that are treated mainly by means of surgical resection, with overall good results. External beam radiotherapy is an alternative treatment for those recurrent tumors, in which a second surgery might not be the best choice for the patient. A little information exists about the effectiveness of gamma knife radiosurgery for the treatment of newly diagnosed and recurrent ETs. We present three cases of ETs treated with gamma knife radiosurgery. Case 1 is a 21-year-old female with an ET located in the left cerebellopontine angle (CPA) with symptoms related to VIII cranial nerve dysfunction. Symptom control was achieved and maintained after single session radiosurgery with gamma knife. Case 2 is a 59-year-old female patient with the history of trigeminal neuralgia secondary to a recurrent ET located in the left CPA. Significant pain improvement was achieved after treatment with gamma knife radiosurgery. Case 3 is a 29-year-old male patient with a CPA ET causing long lasting trigeminal neuralgia, pain relief was achieved in this patient after gamma knife radiosurgery. Long-term symptom relief was achieved in all three cases proving that gamma knife radiosurgery is a good and safe alternative for patients with recurrent or nonsurgically treated ETs.

Flow in potential cascades by means of the finite element method; Flujo en cascadas potenciales mediante el metodo del elemento finito

Energy Technology Data Exchange (ETDEWEB)

Sosa Cordero, Rodolfo; Fernandez Valencia, Gonzalo [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

1987-12-31

This article presents a mathematical model and its solution by means of the finite element method with approximate Garlekin formulation, for the flow analysis in a circular cascade, in a surface of revolution current of a turbo- machine, that can be axial, mixed or radial. To the revolution surface an agreed transformation is applied to obtain a plane, eliminating in this form one term in the equation succeeding in avoiding an iterative solution. Likewise, the finite element method allows to solve the equation in partial derivatives of the elliptical type in its quasi-harmonic form. Additionally, the method followed to introduce the contour conditions is presented; specially, the Kutta-Joukowsky conditions and the one of periodicity, which distinguishes this problem from the classical problems of ideal flows evaluated in the contour. [Espanol] En este articulo se presenta un modelo matematico y su solucion mediante el empleo del metodo del elemento finito con formulacion aproximada de Galerkin, para el analisis del flujo en una cascada circular, en una superficie de corriente de revolucion de una turbomaquina, que puede ser axial, mixta o radial. A la superficie de revolucion se le aplica una transformacion conforme para obtener un plano, eliminando de esta forma un termino en la ecuacion logrando evitar la solucion iterativa. Asimismo, el metodo del elemento finito permite resolver la ecuacion en derivadas parciales del tipo eliptico en su forma cuasiarmonica. Se presenta, ademas, el metodo seguido para introducir las condiciones de contorno; en especial, las condiciones de Kutta-Joukowsky y la de periodicidad, que distinguen a este problema de los problemas clasicos de flujos ideales valuados en el contorno.

Flow in potential cascades by means of the finite element method; Flujo en cascadas potenciales mediante el metodo del elemento finito

Energy Technology Data Exchange (ETDEWEB)

Sosa Cordero, Rodolfo; Fernandez Valencia, Gonzalo [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

1986-12-31

This article presents a mathematical model and its solution by means of the finite element method with approximate Garlekin formulation, for the flow analysis in a circular cascade, in a surface of revolution current of a turbo- machine, that can be axial, mixed or radial. To the revolution surface an agreed transformation is applied to obtain a plane, eliminating in this form one term in the equation succeeding in avoiding an iterative solution. Likewise, the finite element method allows to solve the equation in partial derivatives of the elliptical type in its quasi-harmonic form. Additionally, the method followed to introduce the contour conditions is presented; specially, the Kutta-Joukowsky conditions and the one of periodicity, which distinguishes this problem from the classical problems of ideal flows evaluated in the contour. [Espanol] En este articulo se presenta un modelo matematico y su solucion mediante el empleo del metodo del elemento finito con formulacion aproximada de Galerkin, para el analisis del flujo en una cascada circular, en una superficie de corriente de revolucion de una turbomaquina, que puede ser axial, mixta o radial. A la superficie de revolucion se le aplica una transformacion conforme para obtener un plano, eliminando de esta forma un termino en la ecuacion logrando evitar la solucion iterativa. Asimismo, el metodo del elemento finito permite resolver la ecuacion en derivadas parciales del tipo eliptico en su forma cuasiarmonica. Se presenta, ademas, el metodo seguido para introducir las condiciones de contorno; en especial, las condiciones de Kutta-Joukowsky y la de periodicidad, que distinguen a este problema de los problemas clasicos de flujos ideales valuados en el contorno.

Técnicas de medición de ozono: Métodos tradicionales frente al método de cámara de absorción con led ultravioleta como fuente de luz

Directory of Open Access Journals (Sweden)

Amado Ospina Montoya

2013-08-01

Full Text Available En este artículo se describen las técnicas tradicionales de medición de ozono en la bajaatmósfera. Se hace énfasis en el método de cámara de absorción con diodo Led ultravioleta comofuente de luz por su alto desempeño, y se finaliza con un análisis de las ventajas y desventajas decada método.

Definitive radiation therapy for clinical stage N0-N1 epidermoid carcinoma of the lung

International Nuclear Information System (INIS)

Hayakawa, Kazushige; Mitsuhashi, Norio; Saito, Yoshihiro; Yamakawa, Michitaka; Nakayama, Yuko; Katano, Susumu; Furuta, Masaya; Niibe, Hideo

1993-01-01

From 1976 through 1989, 94 patients with epidermoid carcinoma of the lung without mediastinal nodal involvement were treated with definitive radiation therapy (RT) at Gunma University Hospital. All patients were treated with 10 MV X-rays and the mediastinum was treated in 86% of the patients. The total dose ranged from 60 Gy to 80 Gy with once-daily conventional fractionation. The actuarial two and five-year survival rates of the entire group were 44% and 22%, respectively, with a median survival time (MST) of 17 months. Patients with a performance status of 0-1 lived longer than those with a status of 2 or more (MST 22.5 vs. 12 months). The survival of 60 patients with T2 tumors was better than that of 24 patients with T3 tumors (MST 19 vs. 13.5 months). Forty-seven patients with tumors less than 5 cm in diameter had a two-year progression rate of 25%, in comparison with 39% for 47 patients with tumors greater than 5 cm. The survival difference between these two groups was statistically significant (p<0.01). Patients given a total dose of 80 Gy or over had only 20% local progression at the time of the last follow-up, but they had a lower long-term survival rate than those given a total dose of 60-74 Gy because of the development of pulmonary insufficiency after high-dose irradiation. There was no relapse in the field given 40 Gy or more to the mediastinum for prophylaxis in the patients with no evidence of primary progression. The actuarial five-year survival rates for the patients given 40 Gy or more to the mediastinum, and for the patients given less than 40 Gy were 32% and 9%, respectively. These was a statistically significant difference between these two survival curves, (p<0.05). Differences in survival did not depend on age, sex, or location of the primary tumor. These results should provide support for definitive RT to manage patients with medically inoperable or unresectable epidermoid carcinoma of the lung without mediastinal nodal involvement. (author)

Relación de la radiación ultravioleta y el pterigión primario Relation of ultraviolet radiation and primary pterygium

Directory of Open Access Journals (Sweden)

Belmary Aragonés Cruz

2009-06-01

Full Text Available El pterigión está presente a nivel mundial, pero es más común en climas cálidos y secos, predomina en países comprendidos entre 0º y 30º de latitud norte y sur. Existe evidencia epidemiológica en estudios poblacionales experimentales y observacionales que confirman que la radiación ultravioleta es el desencadenante inicial en la aparición del pterigión y un factor de riesgo significativo en su desarrollo. Los fenómenos físicos y climatológicos que explican la patogenia del pterigión son poco conocidos. La epidemiología del pterigión es una herramienta básica para conocer tanto su incidencia como su prevalencia. A partir de esta revisión nos propusimos reflexionar acerca del pterigión como marcador del grado de insolación del organismo y enfatizar en cuanto a la importancia de protección ante la posible exposición a la radiación ultravioleta en el resultado final de una cirugía de pterigión.Pterygium is present worldwide but it is more common in dry warm climates and predominates in countries situated 0º and 30º on North and South latitudes. There are epidemiological pieces of evidence in experimental and observational population studies that confirm that ultraviolet radiation is the initial unleashing factor in occurrence of pterygium and a significant risk factor for its development. The physical and climate phenomena accounting for the pathogeny of pterygium are almost unknown. Pterygium epidemiology is a basic tool for identifying its incidence and prevalence. On the basis of this review, we intended to make reflections on pterygium as a marker of degree of insolation of the human body and to emphasize the importance of protection against possible exposure to ultraviolet radiations in the final outcome of pterygium surgery.

Radiation therapy of non-resected epidermoid carcinoma of the esophagus

International Nuclear Information System (INIS)

Matsudaira, Naoya

1989-01-01

During the period between January 1972 and March 1987, 72 patients with locoregional or extensive epidermoid carcinomas of the esophagus were treated with radiation. Patients were subdivided into three groups ; 17 patients who received a radiation dose of more than 50 Gy to locoregional carcinomas (curative group), 44 patients who received more than 50 Gy to extensive carcinomas (non-curative group) and 11 patients who received less than 50 Gy to locoregional or extensive carcinomas (palliative group). Both local control and survival rates were excellent and highest in the curative group, followed by the non-curative and palliative groups, respectively. Survival rates at 1, 2, 3, and 5 years were, 50.0, 31.3, 25.0 and 18.8% in the curative group; 23.3, 7.0, 2.4% and no survivors at 4 years in the non-curative group; and 11.1% and no survivors at 2 years in the palliative group, respectively. The median survival periods were 290, 170 and 149 days in the curative, non-curative and palliative group, respectively. Assuming the survival of patients beyond 2 years to be the excellent result of radiation therapy of carcinoma of the esophagus, the favorable factors were determined to be as follows. Stage I or II carcinomas, a tumor length of less than 5 cm, complete tumor response to radiation (CR), duration of symptoms of more than 6 months, and radiation dose of more than 71 Gy. (author)

The growth of human fibroblasts and A431 epidermoid carcinoma cells on gamma-irradiated human amnion collagen substrata.

Science.gov (United States)

Liu, B; Harrell, R; Lamb, D J; Dresden, M H; Spira, M

1989-10-15

Human fibroblasts and A431 human epidermoid carcinoma cells were cultured on gamma-irradiated human amnion collagen as well as on plastic dishes and non-irradiated collagen coated dishes. The morphology, attachment, growth and short-term cytotoxicity of these culture conditions have been determined. Both irradiated and non-irradiated amnion collagen enhanced the attachment and proliferation of fibroblasts as compared to the plastic dishes. No differences in these properties were observed for A431 cells cultured on irradiated collagen when compared with culture on non-irradiated collagen substrates. Cytotoxicity assays showed that irradiated and non-irradiated collagens were not cytotoxic for either fibroblasts or A431 cells. The results demonstrated that amnion collagen irradiated at doses of 0.25-2.0 Mrads is optimal for cell growth.

Radiation therapy for epidermoid carcinoma of the anal canal, clinical and treatment factors associated with outcome

International Nuclear Information System (INIS)

Myerson, Robert J.; Kong, Fengming; Birnbaum, Elisa H.; Fleshman, James W.; Kodner, Ira J.; Picus, Joel; Ratkin, Gary A.; Read, Thomas E.; Walz, Bruce J.

2001-01-01

Background and purpose: In recent years, treatment with combined chemotherapy and radiation has become the standard of care for epidermoid carcinoma of the anus. However, optimal radiotherapy techniques and doses are not well established. Materials and methods: During the period 1975-1997, 106 patients with epidermoid carcinoma of the anal canal underwent radiation therapy. Treatment policies evolved from radiation therapy alone or with surgery, to combined chemotherapy and radiation followed by surgery, to combined chemotherapy and radiation. Results: Overall 74% of patients were NED (no evidence of disease) at last follow-up. The most important clinical correlate with ultimate freedom from disease (includes the contribution of salvage surgery) was extent of disease. The 5-year ultimate freedom from disease was 87±5% for T1/T2N0, 78±10% for T3N0 (15% salvaged by surgery), and 43±10% for either T4N0 or any N+ lesions (P<0.001, Tarone-Ware). There was no difference between planned vs. expectant surgery (5-year ultimate NED: 67±11% planned surgery vs. 73±5% expectant surgery). The most important correlate with late toxicity was a history of major pelvic surgery (surgical vs. non-surgical group: P=0.013, Fisher's exact test, two-tailed summation). Thirty-three additional malignancies have been seen in 26 patients. The most common additional malignancies were gynecologic (nine cases), head and neck (six cases), and lung cancer (five cases). Conclusions: For T1/T2N0 disease, moderate doses of radiation combined with chemotherapy provided adequate treatment. T4N0 and N+ lesions are the most appropriate candidates for investigational protocols evaluating dose intensification. T3N0 tumors may also be appropriate for investigation; however, dose intensification may ultimately prove counterproductive if the cure rate is not improved and salvage surgery is rendered more difficult. The volume of irradiated small bowel should be minimized for patients who have a past

PKI 166 induced redox signalling and apoptosis through activation of p53, MAP kinase and caspase pathway in epidermoid carcinoma.

Science.gov (United States)

Das, Subhasis; Dey, Kaushik Kumar; Bharti, Rashmi; MaitiChoudhury, Sujata; Maiti, Sukumar; Mandal, Mahitosh

2012-01-01

Cellular redox changes have emerged as a pivotal and proximal event in cancer. PKI 166 is used to determine the effects of redox sensitive inhibition of EGFR, metastasis and apoptosis in epidermoid carcinoma. Cytotoxicity study of PKI 166 (IC50 1.0 microM) treated A431 cells were performed by MTT assay for 48 and 72 hrs. Morphological analysis of PKI 166 treated A431 cells for 48 hrs. revealed the cell shrinkage, loss of filopodia and lamellipodia by phase contrast and SEM images in dose dependent manner. It has cytotoxic effects through inhibiting cellular proliferation, leads to the induction of apoptosis, as increased fraction of sub-G1 phase of the cell cycle, chromatin condensation and DNA ladder. It inhibited cyclin-D1 and cyclin-E expression and induced p53, p21 expression in dose dependent manner. Consequently, an imbalance of Bax/Bcl-2 ratio triggered caspase cascade and subsequent cleavage of PARP, thereby shifting the balance in favour of apoptosis. PKI 166 treatment actively stimulated reactive oxygen species (ROS) and mitochondrial membrane depolarization. It inhibited some metastatic properties of A431 cells supressing colony formation by soft agar assay and inhibition of MMP 9 activity by gelatin zymography and western blot analysis. PKI 166 inhibited growth factor induced phosphorylation of EGFR, Akt, MAPK, JNK and colony formation in A431 cells. Thus the inhibition of proliferation was associated with redox regulation of the caspase cascade, EGFR, Akt/PI3K, MAPK/ ERK and JNK pathway. On the other hand, increased antioxidant activity leads to decreased ROS generation inhibit the anti-proliferative and apoptotic properties of PKI 166 in A431 cells. These observations indicated PKI 166 induced redox signalling dependent inhibition of cell proliferation, metastatic properties and induction of apoptotic potential in epidermoid carcinoma.

Ultraviolet radiation response of two heterotropy Antarctic marine bacterial; Respuesta a la radiacion ultravioleta de dos cepas bacterianas marinas heterotrofas antarticas

Energy Technology Data Exchange (ETDEWEB)

Hernandez, Edgardo A [Buenos Aires Univ. (Argentina). Facultad de Farmacia y Bioquimica; Ferreyra, Gustavo A; Mac Cormack, Walter P [Direccion Nacional del Antartico, Buenos Aires (Argentina). Instituto Antartico Argentino

2004-07-01

Two Antarctic marine bacterial strains, were exposed to different irradiance of ultraviolet (UV) solar radiation using several experimental protocols and interferential filters. Results showed that both, UV-A and UV-B radiation produce deleterious effects on two tested bacterial strains. The mortality values under UVB treatments were higher than those observed under UVA treatments. UVvi strain proved to be more resistant to UV radiation than the UVps strain. (author) [Spanish] Dos cepas marinas antarticas fueron expuestas a diferentes irradiancias de radiacion solar ultravioleta (UV) utilizando diferentes protocolos experimentales y filtros interferenciales. Los resultados mostraron que tanto la radiacion UV-A como UV-B produce efectos deletereos sobre las dos cepas bacterianas analizadas. Los valores de mortalidad bajo tratamiento UV-B fueron mayores que los observados bajo tratamiento UV-A. La cepa UVvi mostro mayor resistencia a la radiacion UV que la cepa UVps. (autor)

Subsurface microbial ecology. Epi fluorescence direct counts; Ecologia microbica del sottosuolo: metodo di conta diretta in epifluorescenza

Energy Technology Data Exchange (ETDEWEB)

Barra Caracciolo, A.; Silvestri, C.; Creo, C.; Izzo, G. [ENEA, Centro Ricerche Casaccia, Rome (Italy). Dipt. Ambiente

1998-07-01

To the aim of recognize the importance of microorganisms in affecting or even determining the fate of xenobiotics in the subsurface environment evaluating bacteria concentration in a subsurface ecosystem, the report discusses a soil sample treatment method which has been developed for epi fluorescence direct counting with DAPI. [Italian] Lo studio discute un metodo di trattamento del campione per la conta diretta in epifluorescenza con un marcatore selettivo per il DNA, il DAPI, al fine di quantificare la concentrazione batterica del sottosuolo e studiare il ruolo dei microrganismi nella biodegradazione delle molecole esogene, ancora poco indagato.

Phosphorylation of chloroform soluble compounds in plasma membranes of human epidermoid carcinoma A431 cells

International Nuclear Information System (INIS)

Brautigan, D.L.; Randazzo, P.; Shriner, C.; Fain, J.N.

1985-01-01

This study investigated a possible role for the epidermal growth factor (EGF) receptor protein tyrosine kinase in phosphoinositide metabolism with plasma membrane vesicles from human epidermoid carcinoma (A431) cells. The authors found a novel chloroform-soluble product radiolabeled with [gamma- 32 P]ATP that did not migrate from the origin in the thin layer system designed to separate the phosphoinositides, appeared as a single band of Mr = 3500 on polyacrylamide gels in the presence of dodecyl sulfate, had an ultraviolet absorbance spectrum with a maximum at 275 nm and stained with Coomassie dye. Based on these properties this phosphorylation product is referred to as a proteolipid. The 32 P label was not detected in phosphotyrosine [Tyr(P)], phosphoserine [Ser(P)] or phosphothreonine [Thr(P)] and was lost during acid or base hydrolysis. Phosphorylation of proteolipid was increased significantly by EGF, whereas phosphorylation of phosphatidic acid was decreased and labeling of phosphoinositides was unaffected. Thus, it appears that in A431 membranes the EGF receptor/kinase does not utilize phosphatidylinositol as a substrate, but does phosphorylate a membrane proteolipid

Flow measurement in a 170-MW hydraulic turbine using the Gibson method; Medicion del flujo de una turbina hidraulica de 170 MW utilizando el metodo Gibson

Energy Technology Data Exchange (ETDEWEB)

Urquiza, Gustavo [Universidad Autonoma del Estado de Morelos (Mexico); Adamkowski, Adam [The Szewalski Institute of Fluid-Flow Machinery (Poland); Kubiak, Janusz; Sierra, Fernando [Universidad Autonoma del Estado de Morelos (Mexico); Janicki, Waldemar [The Szewalski Institute of Fluid-Flow Machinery (Poland); Fernandez, J. Manuel [Comision Federal de Electricidad (Mexico)

2007-07-15

This paper describes the methodology applied for measuring water flow through a 170-MW hydraulic turbine. The flow rate was measured using the pressure-time method, also known as the Gibson method. This method uses the well-known water hammer phenomenon in pipelines; in turbine penstocks, for instance. The version of this method used here is based on measuring, during total stop of the water stream, the time-history of pressure change in one section of the turbine penstock and relate it to the pressure in the upper reservoir to which the penstock is connected. The volumetric flow rate is determined from the relevant integration of the measured temporary pressure rise. Flow measurement was possible this way because the influence of the penstock inlet was negligible as far as an error of the measurement is concerned. The length of the penstock was 300 m. Previous experience and a standard IEC-41-1991 were the criteria adopted and applied. A fast and efficient acquisition system, including a 16 bit card, was used. The flow rate was calculated using a computer program developed and tested on several cases. The results obtained with the Gibson method were used for calibration of the on-line flow measuring system based on the Winter-Kennedy method as one of the index methods. This method is very often used for continuous monitoring of the flow rate through hydraulic turbines, when the calibration has been done on site by using the results of measurements obtained by the absolute method. Having measured the flow rate and output power, the efficiency was calculated for any operating conditions. A curve showing the best operating conditions based on the highest efficiency is presented and discussed. The details of the instrumentation, its installation, and the results obtained are discussed in the paper. [Spanish] Este articulo describe la metodologia aplicada para la medicion del flujo en una turbina hidraulica de 170 MW. El flujo se midio utilizando el metodo de presion

Influencia de la turbidez en el efecto antimicrobiano de la luz ultravioleta y de los pulsos luminosos de luz blanca en néctar de naranja (citrus sinensis

Directory of Open Access Journals (Sweden)

Meregildo Silva Ramirez

2010-01-01

Full Text Available La presente investigación tuvo por objetivo determinar la influencia del nivel de turbidez en el efecto antimicrobiano de la luz ultravioleta y luz blanca en néctar de naranja (Citrus sinensis L.. Dicha investigación fue realizada en una cámara de tratamiento de luz UVC con paredes de espejo y una lámpara de luz ultravioleta de 15 watts. El néctar, sometido a un proceso de pasteurización (90 °C, 10 minutos, se inoculó con levadura liofilizada (Saccharomyces cerevisiae, cepa MIT L51, hasta concentraciones de 1.0; 0.1 y 0.01 % (p/p y se determinó la turbidez de las diluciones, reportando valores de turbidez de 10564, 1304 y 813 UTN respectivamente. Las muestras fueron expuestas a tres diferentes dosis, 0.57; 1.14 y 1.71 J/cm2, tomando una muestra testigo denominada “0” minutos, para efectos de análisis inicial de microorganismos. Posteriormente a la aplicación del tratamiento se realizó el recuento en placas, en medio agar Sabouraud. Obtenidos los datos en la lectura de las colonias resultantes se determinó la tasa de supervivencia en cada tratamiento y el valor de la constante de reducción decimal “D” en J/cm2. Dichos datos mostraron que la turbidez, debido a los sólidos disueltos, influencia adversamente la actividad antimicrobiana de la luz UVC. Se concluye que la actividad antimicrobiana expresada en términos de la constante de reducción decimal “D”, bajo las condiciones de tratamiento en el néctar de naranja, depende directamente de la turbidez e indirectamente del la energía total transmitida.

The Comparative Accuracy of the 4 {pi} Liquid Scintillation Counting Method of Radioisotope Standardization; L'exactitude comparee de la methode de comptage 4 {pi} a scintillateurs liquides pour l'etalonnage des radioisotopes; Sravnitel'naya tochnost' 4 {pi} zhidkogo stsintillatsionnogo metoda podscheta standartiziruemykh radioizotopov; Exactitud del metodo de recuento con centelleador liquido 4 {pi} para normalizar radioisotopos, comparada con la de otros metodos

Energy Technology Data Exchange (ETDEWEB)

Steyn, J [National Physical Research Laboratory, Pretoria (South Africa)

1960-06-15

The accuracy of the 4 {pi} liquid scintillation counting method of standardizing {beta} emitters was compared to 4 l{pi} {beta}-{gamma} coincidence counting for the nuclides Co{sup 60}, I{sup 131} and Au{sup 198}. For P{sup 32} the liquid counting results were compared to 4 {pi} proportional counting. The efficiency of the liquid scintillation counting method was found to be energy dependent, dropping to about 97.5% for Co{sup 60} which was the lowest energy {beta} emitter investigated. (author) [French] La precision de la methode de comptage 4 {pi} a scintillateurs liquides pour l'etalonnage des emetteurs {beta} a ete comparee au comptage par coincidences 4 {pi} {beta}-{gamma} pour le So{sup 60}, le I{sup 131} et le Au{sup 198}. Dans le cas du P{sup 32}, les resultats du comptage au liquide ont ete compares a ceux du comptage 4 {pi} proportionnel. On a constate que le rendement de la methode de comptage a scintillateurs liquides variait en fonction de l'energie emise et qu'il descendait a environ 97.5% pour le Co{sup 60} qui, de tous les emetteurs {beta} etudies, emet l'energie la plus faible. (author) [Spanish] El autor compara la precision del metodo de recuento con centelleador iquido 4 {pi} para normalizar emisores {beta} con la del metodo de coincidencias {beta}-{gamma} 4 {pi}, para los siguientes nuclidos: So{sup 60}, I{sup 131} y Au{sup 198}. En el caso del P{sup 32}, confronta los resultados del primer metodo con los obtenidos mediante el recuento proporcional 4 {pi}. Comprueba que la eficacia del metodo de recuento con centelleador liquido depende de la energia y desciende al 97.5%, aproximadamente, para el Co{sup 60}, que fue el emisor {beta} mas debil que se investigo. (author) [Russian] Tochnost' 4 {pi} zhidkogo stsintillyatsionnog o metoda podscheta standartiziruemogo {beta}-izluchatelya sravnivalas' s 4 {pi} {beta}-{gamma} metodom podscheta na sovpadeniyakh dlya izotopov So{sup 60}, I{sup 131} i Au{sup 198}. Dlya R{sup 32} rezultaty zhidkogo

The place of radiotherapy in muco-epidermoid carcinomas of salivary glands in child; Place de la radiotherapie dans les carcinomes mucoepidermoides des glandes salivaires de l'enfant

Energy Technology Data Exchange (ETDEWEB)

Thariat, J. [Centre Antoine-Lacassagne, Nice (France); Temam, S. [Institut Gustave-Roussy, Villejuif (France); Orbach, D. [Institut Curie, Paris (France); Nicollas, R.; Penicaud, M. [Hopital La Timone, Marseille (France); Toussaint, B. [CHU, Nancy (France); Makeieff, M. [CHU, Montpellier (France); Laprie, A. [Institut Claudius-Regaud, Toulouse (France); Castillo, L. [CHU, Nice (France); Vedrin, P. [CHC de Cannes, Cannes (France)

2011-10-15

As muco-epidermoid carcinomas are the most frequent tumours of salivary glands for child, the authors report the study of the role of radiotherapy. This study is based on a survey performed in 34 paediatric departments. The authors analyse the age and gender, the use of irradiation, the tumour location, the tumour grade and size, the use of surgery and of radiotherapy, and survival. Radiotherapy is beneficial for high grade tumours, but cannot be recommended for low and intermediate grades. Short communication

Preparação de Carodnia vieirai (Mammalia: Xenungulata Utilizando Luz Ultravioleta.

Directory of Open Access Journals (Sweden)

Rafael de Castro Medeiros Junger

2007-07-01

Full Text Available A utilização de luz ultravioleta (“luz negra” ouUV, na paleontologia, tem ampla aplicação. Seu êxitoestá nos fósseis calcários, cuja presença de fosfatode cálcio provoca fluorescência do fóssil, o quepermite delimitar, com maior precisão, a presença deestruturas completamente invisíveis ou pouco visíveisà luz natural. Através da fluorescência, em triagensrealizadas a noite, é possível encontrar um maiornúmero de pequenos vertebrados fósseis quandocomparado a triagens realizadas em iluminaçãonormal. A eficiência desse método também foiconstatada na análise um dinossauro Theropoda,revelando uma divisão da cavidade visceral emduas regiões (pleuropericardial anterior e abdominalposterior. O objetivo desse trabalho é reportar osucesso da utilização da luz ultravioleta na montagemdo esqueleto de Carodnia vieirai. Este mamífero,de idade paleocênica, foi encontrado em uma dasfendas que cortava o calcário que preenche a Baciade S. J. de Itaboraí, Rio de Janeiro, Brasil. Apesarde parcialmente preparado, para a reconstituição emontagem do esqueleto houve necessidade da totalremoção de qualquer sedimento antes da confecçãodos moldes. Devido à matriz óssea e o sedimentoapresentarem a mesma coloração e estaremfortemente unidos, a preparação sob luz naturalalgumas vezes provocou danos ao fóssil, devido àdificuldade na diferenciação de ambos. A principioutilizou-se água para aumentar a diferenciação (osedimento úmido fica ligeiramente acinzentado epara facilitar a remoção deste, entretanto, após longaexposição do fóssil à água, este se tornou mais frágile mais facilmente fragmentava-se. Para evitar estesdanos optou-se então pela utilização de luz negra napreparação. Utilizou-se uma lâmpada UV de 18”/15watt, de comprimento de onda entre 400 e 320nm(UVA, e classificada como UV próximo. Tratasede uma lâmpada fluorescente sem a proteçãodo componente (fósforo, que a faz emitir umaluz

Cutaneous epidermoid carcinoma (spinocellular carcinoma): clinical practice recommendations for diagnosis and therapy. Full report

International Nuclear Information System (INIS)

Martin, Ludovic; Bonerandi, Jean-Jacques; Brugneaux, Julie; Beauvillain, Claude; Chassagne, Jean-Francois; Clavere, Pierre; Grolleau, Jean-Louis; Grossin, Maggy; Sei, Jean-Francois; Caquant, Ludovic; Chaussade, Veronique; Desouches, Christophe; Garnier, Francois; Jourdain, Alain; Lemonnier, Jean-Yves; Maillard, Herve; Ortonne, Nicolas; Rio, Emmanuel; Simon, Etienne

2009-01-01

This guide aims at providing practitioners taking into care patients presenting a cutaneous cancer with recommendations based on scientific evidences or expert agreements. More precisely, the objectives are to clarify the terminology used to describe the different forms of cutaneous epidermoid carcinoma (CEC) and of their precursors (actinic keratosis, Bowen's disease), to propose a prognosis classification of CECs adapted to the previously identified prognosis factors, to optimise the diagnosis and therapy of actinic keratosis and Bowen's disease according to recent publications, and to recall the principles of a primary prevention of CECs and of their precursors, and of screening of high risk individuals. Thus, the different parts of this report address the following issues: anatomic-clinical forms and epidemiology of CECs and of their precursors, prognosis factors of CECs, means of treatment of CECs and of their precursors (medical, physical, surgical, radiation-based, and chemical treatments). Radiotherapy notably comprises external radiotherapy and interstitial brachytherapy. Indications for radiotherapy are discussed with respect to existing guides and to the clinical situation. The authors address the care of CECs and of their precursors (prevention, screening and clinical diagnosis, care of invasive CECs, keratoacanthoma treatment). They finally discuss quality criteria aimed at practice improvement, and perspectives regarding the evolution of this guide and studies to be performed

Patrón de alteraciones genético-moleculares en los carcinomas epidermoides de laringe y faringe y en sus correspondientes metástasis linfáticas

OpenAIRE

Alonso Guervós, Marta

2006-01-01

Los carcinomas epidermoides de cabeza y cuello (CECC) ocupan el octavo lugar entre las neoplasias del sexo masculino, presentando el Principado de Asturias una de las tasas de incidencia más altas de España. Aunque se han realizado importantes avances en su diagnóstico y tratamiento, la supervivencia se ha modificado poco en los últimos años debido a que se diagnostican en estadios avanzados. El desarrollo de metástasis en los ganglios linfáticos cervicales es el factor que más influye en la ...

Effect of rutin on virus inactivation by AMT in combination with ultraviolet-A irradiation in platelet concentrates

Energy Technology Data Exchange (ETDEWEB)

Yamada, Yoshiko; Abe, Hideki; Ikebuchi, Kenji; Sekiguchi, Sadayoshi [Hokkaido Red Cross Blood Center, Sapporo (Japan)

1999-10-01

Treatment with psoralens and ultraviolet-A (UVA) irradiation have been found to be effective for virus sterilization of platelet concentrates (PCs). We report here a virus inactivation method using a combination of psoralen derivative 4'-aminomethyl-4,5', 8-trimethylpsoralen (AMT) and UVA irradiation (AMT/UVA). Further, we also investigated the effect of rutin, a radical scavenger, on the inactivation of vesicular stomatitis virus (VSV) as a model virus administered in PCs and platelet functions were investigated. Spiked VSV (about 5log{sub 10}) in PCs was inactivated by a combination of AMT (50 {mu}g/ml) and 5.2 J/cm{sup 2} UVA irradiation in the absence of rutin. To obtain equivalent levels of VSV kill in the presence of 0.35 mM rutin, treatment with 13.0 J/cm{sup 2} of UVA irradiation with AMT was performed. When PCs were treated under each condition in which 5log{sub 10} VSV was inactivated by AMT/UVA with or without rutin, platelet aggregation function was maintained for more than 80% of untreated platelets. These findings indicate that the presence of rutin during AMT/UVA treatment conferred no beneficial effect. In addition, overnight storage of PCs with AMT induced 40% loss of platelet aggregation in response to 10{mu}M ADP. The findings suggest that UVA irradiation is required immediately after the addition of AMT. (author)

Fisetin inhibits growth, induces G2/M arrest and apoptosis of human epidermoid carcinoma A431 cells: Role of mitochondrial membrane potential disruption and consequent caspases activation

Science.gov (United States)

Pal, Harish C.; Sharma, Samriti; Elmets, Craig A.; Athar, Mohammad; Afaq, Farrukh

2013-01-01

Non-melanoma skin cancers (NMSCs) one of the most common neoplasms causes serious morbidity and mortality. Therefore, identification of non-toxic phytochemicals for prevention/treatment of NMSCs is highly desirable. Fisetin (3,3′,4′,7-tetrahydroxyflavone), a dietary flavonoid, present in fruits and vegetables possesses anti-oxidant and anti-proliferative properties. The aim of this study was to investigate the chemotherapeutic potential of fisetin in cultured human epidermoid carcinoma A431 cells. Treatment of A431 cells with fistein (5-80 μM) resulted in a significant decrease in cell viability in a dose- and time-dependent manner. Employing clonogenic assay, we found that fisetin treatment significantly reduced colony formation in A431 cells. Fisetin treatment of A431 cells resulted in G2/M arrest and induction of apoptosis. Furthermore, treatment of A431 cells with fisetin resulted in (i) decreased expression of anti-apoptotic proteins (Bcl2, Bcl-xL and Mcl-1), (ii) increased expression of pro-apoptotic proteins (Bax, Bak and Bad), (iii) disruption of mitochondrial potential, (iv) release of cytchrome c and Smac/DIABLO from mitochondria, (v) activation of caspases, and (vi) cleavage of PARP protein. Pretreatment of A431 cells with the pan-caspase inhibitor (Z-VAD-FMK) blocked fisetin-induced cleavage of caspases and PARP. Taken together, these data provide evidence that fisetin possesses chemotherapeutic potential against human epidermoid carcinoma A431 cells. Overall, these results suggest that fisetin could be developed as a novel therapeutic agent for the management of NMSCs. PMID:23800058

Highly uniform ultraviolet-A quantum-confined AlGaN nanowire LEDs on metal/silicon with a TaN interlayer

KAUST Repository

Priante, Davide; Janjua, Bilal; Prabaswara, Aditya; Subedi, Ram Chandra; Elafandy, Rami T.; Lopatin, Sergei; Anjum, Dalaver H.; Zhao, Chao; Ng, Tien Khee; Ooi, Boon S.

2017-01-01

In this paper, we describe ultraviolet-A (UV-A) light-emitting diodes (LEDs) emitting at 325 nm based on a highly uniform structure of quantum-confined AlGaN quantum-disk nanowires (NWs). By incorporating a 20 nm TaN interlayer between a Ti pre-orienting layer and the silicon substrate, we eliminated the potential barrier for carrier injection and phonon transport, and inhibited the formation of interfacial silicide that led to device failure. Compared to previous reports on metal substrate, we achieved a 16 × reduction in root-mean-square (RMS) roughness, from 24 nm to 1.6 nm, for the samples with the Ti/TaN metal-bilayer, owing to the effective diffusion barrier characteristic of TaN. This was confirmed using energy dispersive X-ray spectroscopy (EDXS) and electron energy loss spectroscopy (EELS). We achieved a considerable increase in the injection current density (up to 90 A/cm2) compared to our previous studies, and an optical power of 1.9 μW for the 0.5 × 0.5 mm2 NWs-LED. This work provides a feasible pathway for both a reliable and stable UV-A device operation at elevated current injection, and eventually towards low-cost production of UV devices, leveraging on the scalability of silicon substrates.

Highly uniform ultraviolet-A quantum-confined AlGaN nanowire LEDs on metal/silicon with a TaN interlayer

KAUST Repository

Priante, Davide

2017-11-02

In this paper, we describe ultraviolet-A (UV-A) light-emitting diodes (LEDs) emitting at 325 nm based on a highly uniform structure of quantum-confined AlGaN quantum-disk nanowires (NWs). By incorporating a 20 nm TaN interlayer between a Ti pre-orienting layer and the silicon substrate, we eliminated the potential barrier for carrier injection and phonon transport, and inhibited the formation of interfacial silicide that led to device failure. Compared to previous reports on metal substrate, we achieved a 16 × reduction in root-mean-square (RMS) roughness, from 24 nm to 1.6 nm, for the samples with the Ti/TaN metal-bilayer, owing to the effective diffusion barrier characteristic of TaN. This was confirmed using energy dispersive X-ray spectroscopy (EDXS) and electron energy loss spectroscopy (EELS). We achieved a considerable increase in the injection current density (up to 90 A/cm2) compared to our previous studies, and an optical power of 1.9 μW for the 0.5 × 0.5 mm2 NWs-LED. This work provides a feasible pathway for both a reliable and stable UV-A device operation at elevated current injection, and eventually towards low-cost production of UV devices, leveraging on the scalability of silicon substrates.

Evaluación de formación y destreza de la asepsia de manos empleando lámpara ultravioleta

Directory of Open Access Journals (Sweden)

Manuela Skodova

2014-09-01

Full Text Available Objetivo principal: La higiene de manos (HM es fundamental para una atención sanitaria limpia y segura. Los futuros profesionales de enfermería deben adquirir conocimientos tanto teóricos como prácticos en materia de HM. Metodología: Se evaluó la técnica de HM, registrando las regiones de las manos con/sin exposición a la solución alcohólica marcada con fluoresceína mediante una lámpara de luz ultravioleta. Resultados principales: Evaluamos 71 alumnos, 56,3 % de 2º curso y 43,7% de 3er curso de Enfermería. El 73,3% fueron mujeres. Realizaron la HM bien o muy bien el 45,1% de los alumnos. Las zonas donde con más frecuencia no se extendió la solución alcohólica fueron los pulgares (54,9% y dorso (46,5%. No hubo diferencias significativas entre los dos cursos. Conclusión principal: El papel de la educación es fundamental para sentar las bases de buenas prácticas en HM, en conocimientos teóricos y en el desarrollo de habilidades y reforzamiento de buenas prácticas.

Valoración de la expresión de Bcl2 y ki-67 en el carcinoma epidermoide de pulmón. Alteraciones génicas asociadas. Correlación con variables anatomoclínicas

OpenAIRE

Montejo Maillo, Beatriz

2011-01-01

[ES]Aparte del estudio clinico del tumor, escasos factores parecen influir en el pornóstico del carcinoma epidermoide de pulmón y en los úlitmos 20 años, apenas se ha modificado la supervivencia [EN]Apart from the clinical study of tumor, few factors appear to influence the porn squamous cell carcinoma of lung and in 20 years last article, has remained largely unchanged survival

Atlas de aves: Un metodo para documentar distribucion y seguir poblaciones

Science.gov (United States)

Robbins, C.S.; Dowell, B.A.; Dawson, D.K.; Alvarez-Lopez, Humberto; Kattan, Gustavo; Murcia, Carolina

1988-01-01

Los Atlas de Aves son proyectos nacionales o regionalies para trazar en mapas la distribucion en reproduccion de cada especie de ave. Ese procedimiento se esta usando en Europa, Australia, Nueva Zelanda, Norteamerica, y partes de Africa. El tama?o de los cuadrados varia de medio grado de latitud y Iongitud hasta 5 x 5 km. El trabajo de campo de cada proyecto exige aproxlmadamente cinco a?os, pero los aficionados pueden llevar a cabo la mayor parte del trabajo. Es posible almacenar los resultados en un computador personal. Hay muchos beneficios: (I) se presenta la distribucion corriente de las aves de la nacion, del estado, o de la Iocalidad; (2) se desarrolla nueva informacion especialmente sobre especies raras o en peligro; (3) se descubren areas que tienen una avlfauna sobresaliente o habitats raros y ayuda a su proteccion, (4) se documentan cambios de dlstribucion; (5) se pueden usar para documentar cambios de poblacion, especialmente en los tropicos donde otros metodos son mas dificiles de usar porque hay muchas especies y no hay muchos observadores calificados en la identificacion de sonidos de las aves; (6) son proyectos buenos de investigacion para estudiantes graduados; (7) los turistas y los jefes de excursiones de historia natural pueden contribuir con muchas informaciones

Estudos sôbre o complemento: I - Ação das radiações de Roentgen e ultravioleta

Directory of Open Access Journals (Sweden)

F. Rocha Lagôa

1953-12-01

Full Text Available Foram procedidas verificações experimentais sôbre o complemento de vários animais (cão, coelho, cobaio, homem, cavalo e boi, visando se determinar a sensibilidade dos mesmos às radiações de Roentgen e ultravioleta. Foi verificado que a temperatura constante de + 10° C, os complementos examinados, não apresentam modificações mesmo após terem sofrido a ação de 112.500 r. Outrossim, o mesmo não acontece quando são êles submetidos às radiações ultravioleta, a inativação que então se processa, varia em tempo de acôrdo com o grau de diluição do complemento no momento da irradiação. A seguir, se demonstrou que a fração complementar sensível a essas radiações é a fração albumina termolabil (segundo componente C2. Os complementos, assim, inativados podem readquirir as suas propriedades mediante a adição da fração albumina proveniente de complemento íntegro, não irradiado. A fração regeneradora pode pertencer a complemento de animal da mesma espécie, e, em alguns casos, a espécies diversas. Assim, a fração albumina do complemento de cobaio, se mostrou capaz de regenerar o complemento inativado do próprio cobaio, do homem, do cão e, parcialmente, o do coelho, não sendo, no entanto ,regenerado por frações albumina originárias de complementos de nenhum dos referidos animais. A fração albumina do complemento humano se revelou capaz de regenerar o próprio complemento humano, o do boi e do cavalo, não sendo, no entanto, regenerado pela fração albumina íntegra proveniente de complemento dêsses dois animais.Where realized experimental observations about some animals complements (dogs, rabbits,guines pigs, mens, horses and cows, verificated the action of roentgen radiations and ultraviolet radiations about than. It was found that the studied complements in constant temperature of 10°C, were not destroyed by the roentgen radiations (112.500 r. The same thing did not happen those submited under

A reverse method to estimate initial temperatures in geothermal reservoirs; Un metodo inverso para estimacion de la temperatura inicial de yacimientos geotermicos

Energy Technology Data Exchange (ETDEWEB)

Garcia Gutierrez, Alfonso [Instituto de Investigaciones Electricas, Gerencia de Geotermia, Cuernavaca, Morelos (Mexico)]. E-mail: aggarcia@iie.org.mx; Ramos Alcantara, Jose R. [Centro Nacional de Investigacion y Desarrollo Tecnologico, Departamento de Ingenieria Mecanica, Cuernavaca, Morelos (Mexico); Arellano Gomez, Victor M. [Instituto de Investigaciones Electricas, Gerencia de Geotermia, Cuernavaca, Morelos (Mexico)

2010-01-15

A method is presented for estimating the initial temperature in geothermal-reservoir formations. The method is based on control theory where the measured temperatures or temperature logs are compared with corresponding simulated temperatures for different times with the well closed. The comparison is made using a control algorithm that makes changes to the originally assumed reservoir temperatures and performs iterations until the best fit between the temperature logs and the simulated temperatures is obtained. The simulation of fluid transport and heat in the well includes the processes of circulation and stop in the presence of circulation losses, modeled on macroscopic balances of momentum and energy. The transport processes in the formation regard the reservoir as an isotropic porous medium and fluid flow is described by Darcy's law. This model generates the fields of temperatures, pressures and speeds as a function of time and space. The method was tested with data from well LV-3 in Las Tres Virgenes geothermal field, Baja California Sur, Mexico. The estimated temperatures of the undisturbed formation-or initial temperatures-are compared within {+-}15 degrees Celsius with the measured temperatures, which is an acceptable outcome from an engineering point of view. [Spanish] Se presenta un metodo para la estimacion de la temperatura inicial en las formaciones de yacimientos geotermicos. El metodo se basa en la teoria de control donde las temperaturas medidas o registros de temperatura se comparan con las correspondientes temperaturas simuladas a diferentes tiempos con el pozo cerrado. La comparacion se hace usando un algoritmo de control el cual hace cambios a las temperaturas de yacimiento originalmente supuestas y realiza iteraciones hasta que se obtiene el mejor ajuste entre los registros de temperatura y las temperaturas simuladas. La simulacion del transporte de fluidos y calor en el pozo incluye los procesos de circulacion y paro en presencia de

Regulation of apoptosis by resveratrol through JAK/STAT and mitochondria mediated pathway in human epidermoid carcinoma A431 cells

International Nuclear Information System (INIS)

Madan, Esha; Prasad, Sahdeo; Roy, Preeti; George, Jasmine; Shukla, Yogeshwer

2008-01-01

Resveratrol (trans-3,4',5-trihydroxystilbene), a polyphenolic phytoalexin present mainly in grapes, red wine and berries, is known to possess strong chemopreventive and anticancer properties. Here, we demonstrated the anti-proliferative and apoptosis-inducing activities of resveratrol in human epidermoid carcinoma A431 cells. Resveratrol has cytotoxic effects through inhibiting cellular proliferation of A431 cells, which leads to the induction of apoptosis, as evident by an increase in the fraction of cells in the sub-G 1 phase of the cell cycle and Annexin-V binding of externalized phosphatidylserine. Results revealed that inhibition of proliferation is associated with regulation of the JAK/STAT pathway, where resveratrol prevents phosphorylation of JAK, thereby inhibiting STAT1 phosphorylation. Furthermore, resveratrol treatment actively stimulated reactive oxygen species (ROS) and mitochondrial membrane depolarization. Consequently, an imbalance in the Bax/Bcl-2 ratio triggered the caspase cascade and subsequent cleavage of PARP, thereby shifting the balance in favor of apoptosis. These observations indicate that resveratrol treatment inhibits JAK/STAT-mediated gene transcription and induce the mitochondrial cell death pathway.

Validation of Hiriart equation to compute steam production by the lip pressure method; Validacion de la ecuacion de Hiriart para calculo de gasto de vapor por el metodo de presion de labio

Energy Technology Data Exchange (ETDEWEB)

Flores Armenta, Magaly [Gerencia de Proyectos Geotermoelectricos de la Comision Federal de Electricidad, Morelia (Mexico)

1996-09-01

Mainly in new geothermal wells, it is necessary to evaluate the production in a very fast, simple and not expensive way, to know the convenience to install surface equipment, such as silencers and separators, to drive the steam to the commercial gathering system. In practice, one of the most known methods is the lip pressure one, which requires a simple set of installations. The objective of this paper is to validate the steam flow rate calculated by the lip pressure method, with respect to the ASME method. The ASME method is known for its accuracy, and is done by measuring the steam and liquid after a high pressure separator, by an orifice plate of known diameter and a triangular weir. Results of the validation show up the feasibility of application of the lip pressure method by using a simple adjustment equation. Percentage of mistake results less than 1%, without any notable influence of the production enthalpy. That equation to be applied in a general case, is as follows: Q{nu} =(20642)(F*P*D{sup 2}/{radical}h-2000). For the particular case of the Los Azufres geothermal field, the equation is: Q{nu}= 810*P*D{sup 2} [Espanol] En los pozos geotermicos, principalmente en los nuevos, es necesario evaluar su produccion de manera rapida, sencilla y economica, para determinar la conveniencia de instalar equipo superficial, como separadores, silenciadores, etc., que permita la integracion del vapor al sistema comercial de generacion electrica. Para fines practicos uno de los metodos mas conocidos es el de presion de labio, que solo requiere un arreglo sencillo de instalaciones superficiales. En este documento se validan y ajustan los calculos de produccion de vapor por ese metodo de presion de labio, con respecto a las mediciones exactas efectuadas con el metodo ASME. Este ultimo es reconocido internacionalmente por su precision, y se lleva a cabo separando la mezcla obtenida en superficie en un recipiente a presion para medir el vapor a traves de una placa de orificio

Application of the identification methods from Hilbert and Prony to the study of oscillatory phenomena in electrical power systems; Aplicacion de los metodos de identificacion de Hilbert y Prony al estudio de fenomenos oscilatorios en sistemas electricos de potencia

Energy Technology Data Exchange (ETDEWEB)

Andrade Soto, Manuel Antonio

2002-10-15

In the present thesis work the application of identification techniques is investigated based on methods of spectral analysis to the study of the instantaneous characteristics of signals obtained by means of digital simulation of the dynamic behavior of the power system. The study focuses on the perspectives developed from two different approaches of analysis: the use of lineal methods of spectral analysis and the use of methods of non-lineal analysis, based on the concept of an analytical signal. The developed tools are applied to the study of two phenomena of electromechanical origin of different characteristics in complex power systems. A comparison between the results obtained is performed for these techniques and the possibility of its application is discussed for the problem of on-line identification in power systems. [Spanish] En el presente trabajo de tesis se investiga la aplicacion de tecnicas de identificacion basadas en metodos de analisis espectral al estudio de las caracteristicas instantaneas de senales obtenidas mediante simulacion digital del comportamiento dinamico del sistema de potencia. El estudio se centra en las aproximaciones desarrolladas desde dos enfoques distintos de analisis: la utilizacion de metodos lineales de analisis espectral y la utilizacion de metodos de analisis no lineal, basados en el concepto de una senal analitica. Las herramientas desarrolladas se aplican al estudio de dos fenomenos de origen electromecanico de caracteristicas distintas en sistemas complejos de potencia. Se hace una comparacion entre los resultados obtenidos por estas tecnicas y se discute la posibilidad de su aplicacion al problema de identificacion en linea en sistemas de potencia.

Aplicación de Dispositivos Móviles en la Medición de los Niveles de Radiación Ultravioleta y su Validación en el Distrito de Chulucanas Región Piura Perú

Directory of Open Access Journals (Sweden)

Lorena Rubio Rubio

2017-02-01

Full Text Available Se denomina App a una aplicación de software que se instala en dispositivos móviles con la finalidad de facilitar al usuario la consecución de tareas, operaciones o gestiones del día a día. La presente investigación desarrolla un análisis sobre la eficiencia de las aplicaciones móviles en la medición de niveles de radiación ultravioleta en el distrito de Chulucanas, con el objetivo de verificar la confiabilidad de los datos obtenidos y fomentar una cultura de prevención a la sobreexposición solar en la población chulucanense para evitar enfermedades relacionadas a la radiación UV. La metodología empleada considera la información procedente de tres aplicaciones móviles previamente seleccionadas, World UV, Uv-Indeks y NoTeQuemes descargadas gratuitamente. La toma de datos es realizada en tres puntos georreferenciados del distrito de Chulucanas que son, ciudad de Chulucanas, caserío Chapica Campanas y caserío Papelillo, la medición se efectúa cinco veces al día cada dos horas, iniciándose a las 8:00 a.m y culminando a las 4:00 p.m, por un período de un mes. Los resultados obtenidos indican la influencia horaria y diaria sobre el desarrollo del nivel de radiación ultravioleta. En los sectores observados se determina que la hora de mayor impacto ocurre al medio día solar, en cuanto al tipo de aplicación móvil más adecuada se considera a UV Indeks por ser el de mejor respuesta de acuerdo a los resultados obtenidos en la bibliografía consultada.

El índice ultravioleta en el ámbito laboral: un instrumento educativo Ultraviolet index in the workspace: a learning tool

Directory of Open Access Journals (Sweden)

Antonio Javier Cortés Aguilera

2011-12-01

Full Text Available Introducción: La exposición a la radiación ultravioleta del sol es un riesgo que sigue sin ser del todo conocido. Este riesgo, al cual está sometida toda la población en general, es especialmente importante para los trabajadores que realizan tareas a la intemperie, ya que a la posible exposición extralaboral (especialmente en los meses de verano se suma una exposición laboral intensa durante muchos meses del año. Esta doble vertiente de exposición al riesgo debe ser tenida en cuenta, por tanto, por los Servicios de Prevención de Riesgos Laborales: desde la perspectiva puramente laboral, a través de las evaluaciones de riesgos y la vigilancia de la salud, y desde la perspectiva extralaboral, a través de campañas / programas de promoción de la salud. Objetivos: Dar a conocer el Índice Ultravioleta (en adelante, IUV como instrumento educativo para la población laboral e integrarlo a nivel individual y colectivo para la adopción de medias preventivas frente a este riesgo dentro y fuera del trabajo. Metodología: Se describen el IUV, los tipos básicos de piel para población europea, el tiempo máximo de exposición solar y el factor de protección solar, para citar las recomendaciones en función del IUV diario, el tipo de piel y el factor de protección. Además, se detallan las medidas para integrar el IUV en la empresa. Conclusiones: El IUV es un instrumento que nos permite llevar el conocimiento y la toma de decisiones basados en él a todos nuestros empleados de una forma clara y sencilla y éstos a su entorno.Introduction: Exposure to ultraviolet radiation (UVR from sunlight is still a risk which is not fully understood. This risk, to which is subject all the general population, is especially important for outdoor workers, because to the possible exposure outside work (especially in summer months we have to add an intense occupational exposure during many months a year. This dual risk of exposure should therefore be taken

Intraparenchymal epidermoid cysts in the brain: diagnostic value of MR diffusion-weighted imaging

Energy Technology Data Exchange (ETDEWEB)

Hu, X.-Y. [Medical Imaging Center, The First Affiliated Hospital of Suzhou, Jiangsu Province (China); Hu, C.-H. [Imaging Center, Soochow University (China)], E-mail: wpdrhxy@hotmail.com; Fang, X.-M.; Cui, L.; Zhang, Q.-H. [Medical Imaging Center, The First Affiliated Hospital of Suzhou, Jiangsu Province (China)

2008-07-15

Aim: To evaluate the value of magnetic resonance (MR) diffusion-weighted imaging (DWI) and apparent diffusion coefficients (ADC) maps in the diagnosis of intraparenchymal epidermoid cysts (ECs). Materials and methods: Six cases of histopathologically proven intraparenchymal ECs were studied. All patients were examined with conventional MR (T1WI, T2WI, contrast-enhanced T1WI) and DWI sequences. Along with the mean ADC values (mADC) of the ECs, the cerebrospinal fluid (CSF) and grey matter (GM) were measured. Qualitative and quantitative assessments, as well as MRI findings, were retrospectively analysed using a double blind method by three radiologists in consensus. Results: Four lesions were located in the cerebellum, among them, one was accompanied by an arachnoid cyst; one huge lesion crossed the parenchyma of the frontal and temporal lobes; the other was located in the left temporal lobe. Two lesions had a homogeneous CSF-like intensity on both T1WI and T2WI. The other four were of mixed-intensity on both T1WI and T2WI. All lesions were strikingly hyperintense on DWI, and iso- or slightly hypointense on ADC (relative to the brain). The mADCs of the ECs were significantly higher than that of GM, but significantly lower than that of CSF. Three cases (3/6) were accurately diagnosed using conventional MR sequences without DWI, but in the remaining three cases, correct diagnosis could only be made with help of DWI. Conclusion: DWI sequences can facilitate the diagnosis of intraparenchymal ECs, thus alerting surgeons of the risk of chemical meningitis at surgery. The MR findings of intraparenchymal ECs are basically as the same as those of extracerebral ECs, but the former is likely to have a mixed signal. The hyperintense signal of ECs on DWI is probably caused by the T2 shine-through effect in tumour tissue.

Carcinoma epidermoide como complicação letal de lesões crônicas de cromoblastomicose Chromoblastomycosis associated with a lethal squamous cell carcinoma

Directory of Open Access Journals (Sweden)

Edoardo Torres

2010-04-01

Full Text Available A cromoblastomicose é uma micose subcutânea, ocasionada por fungos dermatófitos, dos gêneros: Fonsecaea, Phialophora e Cladophialophora. As complicações habituais são: infecções secundárias, linfedema e elefantíase. Em lesões crônicas, tem-se documentado malignização. Relatamos um caso de um homem de 72 anos de idade, com cromoblastomicose de 30 anos de evolução, em região glútea, com desenvolvimento de carcinoma epidermoide.Chromoblastomycosis is a subcutaneous mycosis caused by the dermatophytic fungi Fonsecaea, Phialophora and Cladophialophora. Usual complications include secondary infection, lymphedema and elephantiasis. Associated malignancies have been found in chronic cases. This case report describes a 72 year-old male with a 30 year history of chromoblastomycosis in the gluteal region, who went on to develop a squamous cell carcinoma.

Andrographolide regulates epidermal growth factor receptor and transferrin receptor trafficking in epidermoid carcinoma (A-431) cells

Science.gov (United States)

Tan, Y; Chiow, KH; Huang, D; Wong, SH

2010-01-01

Background and purpose: Andrographolide is the active component of Andrographis paniculata, a plant used in both Indian and Chinese traditional medicine, and it has been demonstrated to induce apoptosis in different cancer cell lines. However, not much is known about how it may affect the key receptors implicated in cancer. Knowledge of how andrographolide affects receptor trafficking will allow us to better understand new mechanisms by which andrographolide may cause death in cancer cells. Experimental approach: We utilized the well-characterized epidermal growth factor receptor (EGFR) and transferrin receptor (TfR) expressed in epidermoid carcinoma (A-431) cells as a model to study the effect of andrographolide on receptor trafficking. Receptor distribution, the total number of receptors and surface receptors were analysed by immunofluorescence, Western blot as well as flow-cytometry respectively. Key results: Andrographolide treatment inhibited cell growth, down-regulated EGFRs on the cell surface and affected the degradation of EGFRs and TfRs. The EGFR was internalized into the cell at an increased rate, and accumulated in a compartment that co-localizes with the lysosomal-associated membrane protein in the late endosomes. Conclusion and implications: This study sheds light on how andrographolide may affect receptor trafficking by inhibiting receptor movement from the late endosomes to lysosomes. The down-regulation of EGFR from the cell surface also indicates a new mechanism by which andrographolide may induce cancer cell death. PMID:20233216

Efecto de la radiación ultravioleta y la colonización micorrízica en árboles pioneros de la región oriental de América del Norte

Directory of Open Access Journals (Sweden)

Nilsen Lasso-Rivas

2015-03-01

Full Text Available Las plantas están expuestas a múltiples factores de estrés que causan alteraciones en su fisiología. Sin embargo, la evidencia sugiere que lasrelaciones mutualistas con microorganismos pueden ayudar a las plantas a superar los efectos perjudiciales de algunos factores de estrés abiótico.El objetivo de esta investigación fue analizar los efectos individuales e interactivos de los rayos ultravioleta (UV (280-400 nm y la simbiosis micorrizíca arbuscular (MA en el crecimiento vegetativo en plántulas de tres especies de árboles pioneros. Se cultivaron en invernadero plántulas de Populusdeltoides, Betula nigra y Salix nigra usando un diseño factorial 2 × 2, con dos condiciones de radiación UV (con y sin radiación UV y dos tratamientosMA (inóculo MA vivo o inóculo MA previamente autoclavado. Después de tres meses, las plantas se cosecharon y se registraron crecimiento, morfología y asignación de biomasa; se evaluó porcentaje de colonización MA mediante técnica de cuadricula. Se encontró que las plántulas expuestasa la radiación UV tenían menor peso seco de la raíz, diámetro del tallo, y relación raíz parte aérea (R/A, y mayor área foliar específica (AFEy razón de área foliar (RAF que aquellas plantas cultivadas en ausencia de radiación UV. La colonización MA no evidenció aumento en el crecimientode las plantas. La radiación ultravioleta redujo el porcentaje de raíz colonizada por hongos MA en plántulas de P. deltoides y S. nigra. Se evidencióque niveles ambientales de radiación UV pueden ejercer un efecto indirecto sobre la micorrización MA en plántulas de árboles pioneros.

Radiación ultravioleta. Análisis de su comportamiento estacional en diferentes sectores de la región Piura. Costa Norte del Perú

Directory of Open Access Journals (Sweden)

Dedios Mimbela Ninell Janett

2016-07-01

Full Text Available Se denomina radiación solar a los conjuntos de radiaciones electromagnéticas emitidas por el sol. Esta energía juega un papel determinante en diversos procesos en la biosfera, siendo uno de los factores importantes en los cambios de clima terrestre. Teniendo en cuenta sus beneficios, también existen los daños que puede causar en animales, plantas y humanos al tener una exposición prolongada. En las últimas dos décadas, se comprobó una disminución gradual de la capa de ozono estimada de 0.4 s 0.5 % por año. En búsqueda de una respuesta sobre el nivel de daño y su dinamismo estacional sobre una región del norte del Perú es por el cual se realiza el análisis del comportamiento del índice de radiación ultravioleta (UV-B. Los resultados, representan una herramienta y una alerta a fin de informar a la población sobre las formas de cómo evitar los problemas e impactos en la piel.

Carcinoma broncogénico epidermoide en un hombre de 21 años Epidermoid bronchogenic carcinoma in a 21 year old black man

Directory of Open Access Journals (Sweden)

John Jairo Duque Alzate

1999-01-01

Full Text Available Hombre de 21 años de edad de raza negra, natural del Chocó (Colombia, quien ha desempeñado diversos oficios; presentó un síndrome de dificultad respiratoria de dos meses de evolución, dolor pleurítico derecho, insuficiencia cardíaca congestiva y síntomas sistémicos. En la necropsia se encontró una masa tumoral blanco-grisácea de 10 x 8 cm, homogénea, con áreas de necrosis, originada en el bronquio principal de los lóbulos inferior y medio derechos y que invadió por vecindad en forma de coraza todo el pericardio causando una pericarditis constrictiva tumoral. El estudio microscópico correspondió a un carcinoma broncogénico tipo epidermoide bien diferenciado. El carcinoma broncogénico se asocia frecuentemente con el consumo de cigarrillo pero su incidencia ha c.umentado entre las personas no fumadoras, lo que sugiere la posibilidad de otros factores que influyen en su presentación como son los contaminantes atmósféricos, la predisposición genética, la dieta deficiente en vitamina A y carotenos, la presencia de ciertos virus y cambios inmunológicos. Este tumor constituye el 16% de todos los cánceres en el hombre y e113% en las mujeres; aparece con mayor frecuencia entre los 40 y los 70 años y sólo del1 al 5% de los casos se presenta en menores de 40 años. A 21 year cid black man, native from Chocó (Colombia, variously employed, who presented with a respiratory difficulty syndrome of two months of evolution, right pleuritic pain, congestive cardiac failure and systemic symptoms. A homogeneic white .grayish tumor measuring 8 by 10 cm with necrotic areas was found at necropsy. The tumor originated in the main bronchial tube of the lower and middle lobes of the right lung and invaded the entire pericardial vicinity forming a cuirass and causing tumoral constrictive pericarditis. Microscopic studies revealed a well differentiated squamous type bronchogenic carcinoma. Bronchogenic carcinomas are frequently associated with

Optimización de un juego de reactivo para determinar fósforo por método ultravioleta Determination of phosphorus presence by UV method and the of a reactant kit optimization

Directory of Open Access Journals (Sweden)

Lisandra García Borges

2009-08-01

Full Text Available Cada día, en la medicina clínica, cobra mayor auge el estudio de las enfermedades relacionadas con la formación del esqueleto y el metabolismo de los minerales, de gran importancia en afecciones renales y las relacionadas con la nutrición, donde desempeña una función primordial el ion fósforo. Con vistas a ofertar a los laboratorios clínicos de Cuba un diagnosticador para determinar fósforo por un método ultravioleta, se formuló un monorreactivo listo para su uso, realizando la optimización de este, así como de la técnica de análisis diseñada para su determinación, la cual es aplicable en los laboratorios clínicos de la red de salud que cuentan con el equipamiento tecnológico para la lectura en el espectro ultravioleta. Se optimizó cada uno de los componentes del monorreactivo, así como la técnica analítica mediante diseños experimentales, y quedaron establecidos los valores óptimos de cada uno. Adicionalmente, se realizó una evaluación con el reactivo optimizado donde se obtuvo una curva lineal en el intervalo de interés clínico y un coeficiente de variación menor del 3 %.Every day, in clinical medicine, increase the interest for the diseases study related to skeletal development and the mineral metabolism, very important in renal affections and those related to nutrition, where it has an essential role the phosphorus ion. To offer Cuban clinical laboratories with diagnosis tool to determine the presence of phosphorus by a UV method, we formulated a monoreactive component ready for use, performing its optimization, as well as of the analysis technique designed to its assessment, which is applicable in clinical laboratories of health network with the technological equipment to read in UV spectrum. Each monoreactive component was optimized, as well as the analytical technique by means of experimental designs, staying the optimal values of each. Also, we performed an assessment using optimized reactive obtaining a

L’utilizzo della ricostruzione nella comunicazione del patrimonio archeologico. L’approccio, il metodo, le finalità e alcuni spunti di discussione.

Directory of Open Access Journals (Sweden)

Elena Bacci

2010-05-01

In questo contributo si focalizza l’attenzione sulla ricostruzione grafica e virtuale del patrimonio e sulle sensazioni che la ricostruzione evoca nel fruitore del messaggio culturale. La ricostruzione si attua mediante la collaborazione tra archeologo e illustratore e costituisce un momento di verifica visiva dell’interpretazione archeologica e uno strumento di comunicazione del dato archeologico fruibile a più livelli. Ciò avviene grazie allo scambio costante di informazioni (dati scientifici e proposte di ricostruzione e il confronto che ne deriva determina i metodi e le fasi di avanzamento del progetto. Il metodo si basa sull’integrazione delle immagini 3D con il disegno tradizionale ed è finalizzato alla trasposizione del dato archeologico, in modo tale da garantire alla ricostruzione il duplice requisito di soddisfazione estetica e credibilità scientifica.

Modulation of clonogenicity, growth, and radiosensitivity of three human epidermoid tumor cell lines by a fibroblastic environment

International Nuclear Information System (INIS)

Gery, Bernard; Little, John B.; Coppey, Jacques

1996-01-01

Purpose: To develop a model vitro system to examine the influence of fibroblasts on the growth and survival of human tumor cells after exposure to ionizing radiation. Methods and Materials: The cell system consists of three epidermoid carcinoma cell lines derived from head and neck tumors having differing growth potentials and intrinsic radiosensitivities, as well as a low passage skin fibroblast strain from a normal human donor. The tumor cells were seeded for five days prior to exposure to radiation: (a) in the presence of different numbers of fibroblasts, (b) in conditioned medium from stationary fibroblast cultures, and (c) on an extracted fibroblastic matrix. Results: When grown with fibroblasts, all three tumor cell lines showed increased clonogenicity and increased radioresistance. The radioprotective effect was maximal at a density of approximately 10 5 fibroblasts/100 mm Petri dish, and was greatest in the intrinsically radiosensitive tumor cell line. On the other hand, the effects of incubation with conditioned medium or on a fibroblastic matrix varied among the tumor cell lines. Thus, the protective effect afforded by coculture with fibroblasts must involve several cellular factors related to the fibroblast itself. Conclusions: These observations emphasize the importance of cultural conditions on the apparent radiosensitivity of human tumor cell lines, and suggest that the fibroblastic connective tissue enveloping the malignant cells should be considered when the aim is to establish a radiopredictive assay from surgical tumors fragments

Ultrastructure of Pericystic or Intracystic Blood Vessels in Epidermoid Cysts-A Transmission Electron Microscopy Study: Laboratory Investigation.

Science.gov (United States)

Ren, Xiao-Hui; Ma, Jun; Zeng, Chun; Sun, Yi-Lin; Lin, Song

2017-07-01

Recently, we reported a tendency toward spontaneous hemorrhage in both the preoperative and postoperative periods in patients with intracranial epidermoid cyst (EC). According to our experience, this tendency for spontaneous hemorrhage was partly caused by the pathologic blood vessels adjacent to the EC. This study was designed to testify this hypothesis. Twenty-three removable pericystic or intracystic blood vessels from 17 patients with EC were collected during surgery and were then examined by transmission electron microscopy. The microvascular structure in gliomas was chosen as the control. Under electron microscopy, variant pathologic changes of vessels were found in all patients with EC. In the tunicae intima, we found vacuolization, apoptosis, necrosis, and intralumenal protrusion of endothelial cells, as well as swollen basement and highly flexed and discontinued elastic plate. In the tunicae media, vacuolization and swollen mitochondria were found in muscular cells. In the tunicae adventitia, extravascular erythrocytes, edema or apoptosis of pericytes, collagen predominance, and inflammatory cell infiltration and destruction were found. Neuron denature and necrosis were found in the peripheral brain tissue. In the microvascular structure of 5 glioma specimens, we found enlargement and hyperplasia of endothelial cells, swollen basement membrane, swollen pericytes, and astrocytic hyperplasia and neuron denature in adjacent brain tissues. Our findings provide strong evidence for the hypothesis that intracystic or pericystic vascular degeneration or destruction accounts for the spontaneous hemorrhage tendency before and after surgical resection of ECs. Copyright © 2017 Elsevier Inc. All rights reserved.

A review of calculation methods for fast and intermediate reactors; Expose des methodes pour le calcul de reacteurs a neutrons rapides et intermediaires; Obzor metodov rascheta reaktorov na promezhutochnykh i bystrykh nejtronakh; Estudio panoramico de los metodos de calculo de los reactores rapidos e intermedios

Energy Technology Data Exchange (ETDEWEB)

Marchuk, G I [Akademiya Nauk, Moskva, Union of Soviet Socialist Republics (Russian Federation)

1962-03-15

This paper discusses the development of methods for calculating intermediate and fast reactors. It deals with various approaches to the problems of physical calculation. The calculation of resonance effects is discussed. Consideration is given to multi-group systems of fundamental and conjugate equations, various applications of perturbation theory to the problems of physical reactor calculation, and numerical methods of solving fundamental and conjugate reactor equations, which approximate the method of spherical harmonics. The paper describes an application of the response method to the solution of critical-mass problems, and methods of calculating reactors with hydrogeneous moderators. The fundamental features of an effective one-group reactor model are described. (author) [French] L'auteur examine la mise au point de methodes pour le calcul de reacteurs a neutrons rapides et intermediaires . Il decrit diverses manieres d'aborder les problemes des calculs sur la physique des reacteurs, notamment le calcul des effets de resonance. Il s'attache particulierement aux points suivants: systemes d'equations fondamentales et conjuguees a plusieurs groupes; diverses applications de la theorie des perturbations aux problemes de calculs sur la physique des reacteurs; methodes numeriques pour resoudre les equations fondamentales et conjuguees, voisines de la methode des harmoniques spheriques. L'auteur decrit ensuite une maniere d'appliquer la methode de la reponse aux problemes de la masse critique ainsi que des methodes pour le calcul de reacteurs ralentis a l'hydrogene. Il decrit les caracteristique s fondamentale s d'un modele de reacteur a un groupe effectif. (author) [Spanish] El autor analiza el desarrollo de los metodos de calculo de los reactores nucleares que trabajan con neutrones rapidos y con neutrones intermedios. Examina diversos planteos de los problemas del calculo fisico. Indica la forma de tomar en cuenta los efectos de resonancia y menciona los sistemas

Factors application of MW-mile method and participation in the allocation of charges by the drills use in electricity markets; Aplicacion de los factores de participacion y del metodo de MW-milla en la asignacion de cargos por uso de redes de transmision en mercados de electricidad

Energy Technology Data Exchange (ETDEWEB)

Alba-Gomez, L; Tovar-Hernandez, J. H; Gutierrez-Alcaraz, G [Instituto Tecnologico de Morelia, Michoacan (Mexico)]. E-mail: horaciotovar@mexico.com; ggutier@itmorelia.edu.mx

2007-04-15

Use of network allocation costs by shift factors and MW-Mile method is reported in this paper. Conventional shift factors are computed based on DC power flow. DC power flow requires to selecting a slack bus in order to avoid matrix singularity. Therefore, shift factors are slack bus dependent. In order to evade slack bus dependency, two approaches are considered. [Spanish] Este trabajo presenta la asignacion de costos por uso de red mediante la aplicacion de Factores de Participacion (FP) y el metodo de MW-Milla. Los FP clasicos son calculados a partir del modelo lineal de flujos de potencia para lo que se requiere de establecer un nodo de referencia a fin de eliminar la singularidad de la matriz de coeficientes. Por lo tanto, los FP son dependientes de la asignacion del nodo de referencia. Dos metodos alternativos para evitar la dependencia del nodo compensador en la obtencion de los factores de participacion son presentados.

Epidermoid cyst in the cerebellopontine angle cistern presenting as trigeminal neuralgia. Diagnostic values of the orbicularis oculi reflex and metrizamide CT cisternography - case report -

Energy Technology Data Exchange (ETDEWEB)

Ueda, Takashi; Goya, Tomokazu; Kinoshita, Kazuo (Miyazaki Medical College, Miyazaki (Japan)); Fukui, Masashi

1983-05-01

This 29-year-old male had been suffering from left trigeminal neuralgia one year prior to admission. Admission was prompted by the development of pain in the third division of the left trigeminal nerve. Physical and neurological examinations were not remarkable except for the facial pain. The orbicularis oculi reflex showed delayed latency of R/sub 1/ on the affected side. CT scans performed pre- and post-contrast enhancement revealed a low density area in the left cerebellopontine angle cistern. Metrizamide CT cisternography clearly revealed the margin of the lesion as the contrast media did not enter into the low density area. A left suboccipital craniectomy was performed. The trigeminal nerve was surrounded by a thin-capsulated mass and cholesteatoma materials. Histological diagnosis was epidermoid cyst. Since this surgical procedure, the trigeminal neuralgia has not recurred for one year. Without objective neurological deficits, it is difficult to distinguish symptomatic trigeminal from idiopathic neuralgia. Therefore, minor change of the orbicularis oculi reflex should help in objectively detecting dysfunction of the trigeminal nerve. Metrizamide CT cisternography is also useful in diagnosis of cystic lesions.

A method for optimization of patient dose estimation in conventional radiology; Un metodo per l'ottimizzazione della stima della dose al paziente nella radiologia tradizionale

Energy Technology Data Exchange (ETDEWEB)

Tofani, A.; Del Corona, A. [Azienda Unita' Sanitaria Locale 6, Livorno (Italy). Unita' Ospedaliera di Fisica Sanitaria; Niespolo, A. [Azienda Ospedaliera Pisana, Pisa (Italy). Unita' Ospedaliera di Fisica Sanitaria

2000-05-01

found to depend on the average body surface, a parameter which takes into account both patient height and mass. Thus, determining the normalization factor for each projection and each view allows to estimate the absorbed dose under different geometrical conditions. The method has been verified by considering four of the most common X-ray procedures (chest AP, cervical spine LAT, lumbar spine AP and head LAT). The average error on dose estimation is about 13 %. In the very next future the method will be extended to all the projections and views of ICRP Report no. 34, and we plant to integrate the described algorithm in a computer program devoted to the automatic computation of patient dose. [Italian] Il metodo raccomandato dalla International Commission on Radiological Protection (ICRP) nel suo Report n. 34(1982) per il calcolo della dose al paziente negli esami di radiodiagnostica e' basato su dati dosimetrici tabulati ottenuti mediante simulazioni Monte Carlo su fantocci antropomorfi descritti da semplici funzioni matematiche. Nel caso del calcolo della dose per un paziente adulto, le limitazioni principali di questo metodo sono due: in primo luogo i parametri geometrici dell'esame - e in particolare la distanza fuoco-pellicola e il formato della pellicola- sono fissi, e questo rende problematico l'utilizzo dei dati dosimetrici nelle condizioni effettive in cui si e' svolto l'esame, che in genere non coincideranno con quelle standard ICRP. Inoltre quando le dimensioni e la massa del paziente differiscono sensibilmente da quelle del fantoccio utilizzato nelle simulazioni (il cosidetto uomo di riferimento, di altezza pari a 174 cm e massa di 70,9 Kg) il metodo ICRP puo' portare a errori considerevoli nella stima della dose. Lo scopo del presente lavoro e' quello di indicare una possibile via di uscita per superare queste limitazioni. L'algoritmo proposto in questo lavoro si basa sull'applicazione del metodo suggerito da Huda e

Combinatorial effects of geopropolis produced by Melipona fasciculata Smith with anticancer drugs against human laryngeal epidermoid carcinoma (HEp-2) cells.

Science.gov (United States)

Bartolomeu, Ariane Rocha; Frión-Herrera, Yahima; da Silva, Livia Matsumoto; Romagnoli, Graziela Gorete; de Oliveira, Deilson Elgui; Sforcin, José Maurício

2016-07-01

The identification of natural products exerting a combined effect with therapeutic agents could be an alternative for cancer treatment, reducing the concentration of the drugs and side effects. Geopropolis (Geo) is produced by some stingless bees from a mixture of vegetable resins, gland secretions of the bees and soil. It has been used popularly as an antiseptic agent and to treat respiratory diseases and dermatosis. To determine whether Geo enhances the anticancer effect of carboplatin, methotrexate and doxorubicin (DOX), human laryngeal epidermoid carcinoma (HEp-2) cells were treated with Geo alone or in combination with each drug. Cell growth, cytotoxicity and apoptosis were evaluated using 3-(4,5-dimethyl thiazol-2yl)-2,5-diphenyltetrazolium bromide (MTT) assay, lactate dehydrogenase (LDH) release, and flow cytometry. Scratch assay was used to analyze cell migration and transmission electron microscopy to observe morphologic alterations. The influence of Geo on drug resistance was also investigated assessing P-glycoprotein (P-gp) action. Geo inhibited cell proliferation and migration. The combination Geo+DOX led to the highest cytotoxic activity and induced apoptosis, leading to loss of membrane integrity. Geo had no effect on P-gp-mediated efflux of DOX. Data indicate that Geo combined with DOX could be a potential clinical chemotherapeutic approach for laryngeal cancer treatment. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

JNK signaling maintains the mesenchymal properties of multi-drug resistant human epidermoid carcinoma KB cells through snail and twist1

International Nuclear Information System (INIS)

Zhan, Xia; Feng, Xiaobing; Kong, Ying; Chen, Yi; Tan, Wenfu

2013-01-01

In addition to possess cross drug resistance characteristic, emerging evidences have shown that multiple-drug resistance (MDR) cancer cells exhibit aberrant metastatic capacity when compared to parental cells. In this study, we explored the contribution of c-Jun N-terminal kinases (JNK) signaling to the mesenchymal phenotypes and the aberrant motile capacity of MDR cells utilizing a well characterized MDR cell line KB/VCR, which is established from KB human epidermoid carcinoma cells by vincristine (VCR), and its parental cell line KB. Taking advantage of experimental strategies including pharmacological tool and gene knockdown, we showed here that interference with JNK signaling pathway by targeting JNK1/2 or c-Jun reversed the mesenchymal properties of KB/VCR cells to epithelial phenotypes and suppressed the motile capacity of KB/VCR cells, such as migration and invasion. These observations support a critical role of JNK signaling in maintaining the mesenchymal properties of KB/VCR cells. Furthermore, we observed that JNK signaling may control the expression of both snail and twist1 in KB/VCR cells, indicating that both snail and twist1 are involved in controlling the mesenchymal characteristics of KB/VCR cells by JNK signaling. JNK signaling is required for maintaining the mesenchymal phenotype of KB/VCR cells; and JNK signaling may maintain the mesenchymal characteristics of KB/VCR cells potentially through snail and twist1

JNK signaling maintains the mesenchymal properties of multi-drug resistant human epidermoid carcinoma KB cells through snail and twist1.

Science.gov (United States)

Zhan, Xia; Feng, Xiaobing; Kong, Ying; Chen, Yi; Tan, Wenfu

2013-04-04

In addition to possess cross drug resistance characteristic, emerging evidences have shown that multiple-drug resistance (MDR) cancer cells exhibit aberrant metastatic capacity when compared to parental cells. In this study, we explored the contribution of c-Jun N-terminal kinases (JNK) signaling to the mesenchymal phenotypes and the aberrant motile capacity of MDR cells utilizing a well characterized MDR cell line KB/VCR, which is established from KB human epidermoid carcinoma cells by vincristine (VCR), and its parental cell line KB. Taking advantage of experimental strategies including pharmacological tool and gene knockdown, we showed here that interference with JNK signaling pathway by targeting JNK1/2 or c-Jun reversed the mesenchymal properties of KB/VCR cells to epithelial phenotypes and suppressed the motile capacity of KB/VCR cells, such as migration and invasion. These observations support a critical role of JNK signaling in maintaining the mesenchymal properties of KB/VCR cells. Furthermore, we observed that JNK signaling may control the expression of both snail and twist1 in KB/VCR cells, indicating that both snail and twist1 are involved in controlling the mesenchymal characteristics of KB/VCR cells by JNK signaling. JNK signaling is required for maintaining the mesenchymal phenotype of KB/VCR cells; and JNK signaling may maintain the mesenchymal characteristics of KB/VCR cells potentially through snail and twist1.

Iridium-192 curietherapy for T1 and T2 epidermoid carcinomas of the floor of mouth

International Nuclear Information System (INIS)

Mazeron, J.J.; Grimard, L.; Raynal, M.; Haddad, E.; Piedbois, P.; Martin, M.; Marinello, G.; Nair, R.C.; Le Bourgeois, J.P.; Pierquin, B.

1990-01-01

From 1970 to 1986, 117 patients with T1 (47) or T2 (70) epidermoid carcinomas of the floor of the mouth (SCC) were treated by iridium-192 implantation (192 Ir). The dose was prescribed according to the Paris System and varied over those years. Follow-up information was available on 116 patients. There were 46 T1N0, 47 T2N0, and 23 T2N1-3. Neck management varied for the 93 N0 patients consisting of surveillance (24 T1, 17 T2) or elective neck dissection (22 T1:all pN-, 30 T2: 20 pN-, 10 pN+). Cause specific survival rates were 94% for T1N0, 61.5% for T2N0, and 28% for T2N1-3 at 5 years. Primary local control was 93.5%, 74.5%, and 65%, respectively, and 98%, 79%, and 65% after salvage. Patients with gingival extension or a tumor size over 3 cm (T2b) had a local control of 50% (9/18) and 58% (15/26), respectively. Nodal control was 93.5% for Stage I, 85% for Stage II, and 48% for T2N1-3 patients. There was no difference in nodal control with regard to treatment policy for Stage I-II patients. There were few complications including three deaths: two from surgery and one from 192 Ir. Nodal status, tumor size defined as T1, T2a (less than or equal to 3 cm), T2b (greater than 3 cm), and gingival extension were the only independent prognostic factors. The management of T1N0 and T2N0 SCC by 192 Ir to a dose of 65 or 70 Gy, using the Paris System, is recommended for lesions 3 cm or less and without gingival extension

Survey of Pulsed Neutron Source Methods for Multiplying Media; Methodes des Neutrons Pulses Pour l'Etude des Milieux Multiplicateurs; Obzor metodov s ispol'zovaniem istochnikov impul'snykh nejtronov dlya razmnozhayushchej sredy; Estudio Panoramico de los Metodos de Empleo de Fuentes de Neutrons Pulsados en Medios Multiplicadores

Energy Technology Data Exchange (ETDEWEB)

Garelis, E. [General Electric Company, Vallecitos Atomic Laboratory, Pleasanton, CA (United States)

1965-10-15

-Small-L ). Il discute en outre l'emploi des methodes qui sont fondees sur la reponse a des impulsions pseudoaleatoires et utilisent une correlation entre l'entree et la sortie, pour la determination de la fonction de Green d'un milieu multiplicateur. H montre que les renseignements obtenus par ces methodes sont identiques a ceux fournis par les methodes de la source puisee a repetition, ce qui permet d'appliquer aux premieres les procedes qui ont ete mis au point pour les secondes. (author) [Spanish] En los ultimos afios ha habido dos tendencias principales acerca de la manera mas eficaz de medir la reactividad de parada, empleando fuentes de neutrones pulsados: la primera preconizaba el empleo de metodos tradicionales de medicion con fuentes neutronicas reiteradamente pulsadas, y la segunda propugnaba la aplicacion de metodos basados en una tecnica seudoaleatoria de respuesta a los impulsos, utilizando una correlacion entre los datos de entrada y los de salida. La informacion obtenida con una y otra tecnica es la misma; en teoria, ambos metodos sirven para determinar la funcion de respuesta. Se resefia el desarrollo de las tecnicas de empleo de fuentes de neutrones pulsados aplicadas a sistemas termicos con miras a medir la reactividad, desde los primeros intentos de Sjoestrand hasta el reciente metodo (k{beta}/ Script-Small-L ). Con el metodo usual de empleo de estas fuentes, la propiedad que se procuia determinar es la funcion de Green del conjunto subercritico empleado, es decir, la respuesta del reactor a una fuente de neutrones de funcion delta. El decrecimiento exponencial (e{sup {alpha}t}) de la funcion de Green proporciona una constante de decrecimiento de los neutrones instantaneos que es independiente del espacio. El autor examina los metodos para obtener el valor de la reactividad partiendo de la medida de a, como por ejemplo el metodo de la medicion de la criticidad por neutrones retardados a y el reciente metodo (k{beta}/ Script-Small-L ). Seguidamente examina el

Resveratrol enhances ultraviolet B-induced cell death through nuclear factor-κB pathway in human epidermoid carcinoma A431 cells

International Nuclear Information System (INIS)

Roy, Preeti; Kalra, Neetu; Nigam, Nidhi; George, Jasmine; Ray, Ratan Singh; Hans, Rajendra K.; Prasad, Sahdeo; Shukla, Yogeshwer

2009-01-01

Resveratrol has been reported to suppress cancer progression in several in vivo and in vitro models, whereas ultraviolet B (UVB), a major risk for skin cancer, is known to induce cell death in cancerous cells. Here, we investigated whether resveratrol can sensitize A431 human epidermoid carcinoma cells to UVB-induced cell death. We examined the combined effect of UVB (30 mJ/cm 2 ) and resveratrol (60 μM) on A431 cells. Exposure of A431 carcinoma cells to UVB radiation or resveratrol can inhibit cell proliferation and induce apoptosis. However, the combination of resveratrol and UVB exposure was associated with increased proliferation inhibition of A431 cells compared with either agent alone. Furthermore, results showed that resveratrol and UVB treatment of A431 cells disrupted the nuclear factor-kappaB (NF-κB) pathway by blocking phosphorylation of serine 536 and inactivating NF-κB and subsequent degradation of IκBα, which regulates the expression of survivin. Resveratrol and UVB treatment also decreased the phosphorylation of tyrosine 701 of the important transcription factor signal transducer activator of transcription (STAT1), which in turn inhibited translocation of phospho-STAT1 to the nucleus. Moreover, resveratrol/UVB also inhibited the metastatic protein LIMK1, which reduced the motility of A431 cells. In conclusion, our study demonstrates that the combination of resveratrol and UVB act synergistically against skin cancer cells. Thus, resveratrol is a potential chemotherapeutic agent against skin carcinogenesis.

Resveratrol enhances ultraviolet B-induced cell death through nuclear factor-{kappa}B pathway in human epidermoid carcinoma A431 cells

Energy Technology Data Exchange (ETDEWEB)

Roy, Preeti; Kalra, Neetu; Nigam, Nidhi; George, Jasmine [Proteomics Laboratory, Indian Institute of Toxicology Research (CSIR), P.O. Box 80, M.G. Marg, Lucknow 226 001 (India); Ray, Ratan Singh; Hans, Rajendra K. [Photobiology Laboratory, Indian Institute of Toxicology Research (CSIR), P.O. Box 80, M.G. Marg, Lucknow 226 001 (India); Prasad, Sahdeo [Proteomics Laboratory, Indian Institute of Toxicology Research (CSIR), P.O. Box 80, M.G. Marg, Lucknow 226 001 (India); Shukla, Yogeshwer, E-mail: yogeshwer_shukla@hotmail.com [Proteomics Laboratory, Indian Institute of Toxicology Research (CSIR), P.O. Box 80, M.G. Marg, Lucknow 226 001 (India)

2009-06-26

Resveratrol has been reported to suppress cancer progression in several in vivo and in vitro models, whereas ultraviolet B (UVB), a major risk for skin cancer, is known to induce cell death in cancerous cells. Here, we investigated whether resveratrol can sensitize A431 human epidermoid carcinoma cells to UVB-induced cell death. We examined the combined effect of UVB (30 mJ/cm{sup 2}) and resveratrol (60 {mu}M) on A431 cells. Exposure of A431 carcinoma cells to UVB radiation or resveratrol can inhibit cell proliferation and induce apoptosis. However, the combination of resveratrol and UVB exposure was associated with increased proliferation inhibition of A431 cells compared with either agent alone. Furthermore, results showed that resveratrol and UVB treatment of A431 cells disrupted the nuclear factor-kappaB (NF-{kappa}B) pathway by blocking phosphorylation of serine 536 and inactivating NF-{kappa}B and subsequent degradation of I{kappa}B{alpha}, which regulates the expression of survivin. Resveratrol and UVB treatment also decreased the phosphorylation of tyrosine 701 of the important transcription factor signal transducer activator of transcription (STAT1), which in turn inhibited translocation of phospho-STAT1 to the nucleus. Moreover, resveratrol/UVB also inhibited the metastatic protein LIMK1, which reduced the motility of A431 cells. In conclusion, our study demonstrates that the combination of resveratrol and UVB act synergistically against skin cancer cells. Thus, resveratrol is a potential chemotherapeutic agent against skin carcinogenesis.

An experimental two-stage rat model of lung carcinoma initiated by radon exposure

International Nuclear Information System (INIS)

Poncy, J.L.; Laroque, P.; Fritsch, P.; Monchaux, G.; Masse, R.; Chameaud, J.

1992-01-01

We present the results of a two-stage biological model of lung carcinogenesis in rats. The histogenesis of these tumors was examined, and DNA content of lung cells was measured by flow cytometry during the evolving neoplastic stage. Tumors were induced in rat lungs after radon inhalation (1600 WLM) followed by a promoter treatment; six intramuscular injections of 5,6-benzoflavone (25 mg/kg of body weight/injection) every 2 wk. Less than 3 mo after the first injection of benzoflavone, squamous cell carcinoma was observed in the lungs of all rats exposed to radon. The preneoplastic lesions gradually developed as follows: hyperplastic bronchiolar-type cells migrated to the alveoli from cells that proliferated in bronchioles and alveolar ducts; initial lesions were observed in almost all respiratory bronchioles. From some hyperplasias, epidermoid metaplasias arose distally, forming nodular epidermoid lesions in alveoli, which progressed to form squamous papilloma and, finally, epidermoid carcinomas. The histogenesis of these experimentally induced epidermoid carcinomas showed the bronchioloalveolar origin of the tumor. This factor must be considered when comparing these with human lesions; in humans, lung epidermoid carcinomas are thought to arise mainly in the first bronchial generations. The labeling index of pulmonary tissue after incorporation of 3 H-thymidine by the cells was 0.2% in control rats. This index reached a value of 1 to 2% in the hyperplastic area of the bronchioles and 10 to 15% in epidermoid nodules and epidermoid tumors, respectively. DNA cytometric analysis was performed on cell suspensions obtained after enzymatic treatment of paraffin sections of lungs from rats sacrificed during different stags of neoplastic transformations. Data showed the early appearance of a triploid cell population that grew during the evolution of nodular epidermoid lesions to epidermoid carcinomas

Metástasis cervical contralateral en el carcinoma epidermoide de la cavidad oral: Estudio clínico analítico retrospectivo en 315 pacientes primariamente tratados con cirugía Contralateral neck metastasis in squamous cell carcinoma of the oral cavity: An analytical retrospective clinical study of 315 patients primarily treated with surgery

Directory of Open Access Journals (Sweden)

R. González-García

2008-06-01

Full Text Available Objetivos. Existen en la literatura numerosos estudios en relación con los factores pronósticos implicados en la aparición de metástasis cervicales ipsilaterales en el carcinoma epidermoide de cavidad oral. Sin embargo, no existen estudios clínicos amplios acerca de la asociación de factores clínico-patológicos y la aparición de metástasis cervicales contralaterales tras la resección quirúrgica del tumor primario. El propósito de este estudio es el análisis de los factores implicados en la aparición de metástasis cervical contralateral en pacientes con carcinoma epidermoide de cavidad oral primariamente tratados con cirugía. Pacientes y métodos. Se analizó una serie de 315 pacientes consecutivos con carcinoma epidermoide de la cavidad oral no tratados previamente. Se realizó un estudio complementario del subgrupo de 203 pacientes con carcinoma epidermoide del borde lateral de la lengua libre, por tratarse de un grupo muy prevalente en la serie analizada. Todos los pacientes recibieron tratamiento quirúrgico con o sin tratamiento radioterápico adyuvante. Varias fueron las variables clínicas e histopatológicas analizadas, como son: las características clínicas del tumor, el estadio tumoral, el grado de diferenciación histológica, el tipo de disección cervical, la supervivencia enfermedad- específica, los márgenes quirúrgicos en la pieza resecada, la extensión ganglionar extracapsular, la diseminación perineural y la afectación ósea. Resultados. La duración media del seguimiento de los pacientes que sobrevivieron fue de 70,9 ± 49,6 meses. Ochenta y tres pacientes murieron a causa de la enfermedad a lo largo del seguimiento. Cuarenta y siete de estos pertenecían al subgrupo de pacientes con carcinoma epidermoide de lengua. Un total de 147 pacientes permanecía vivo sin evidencias de recurrencia de la enfermedad al final del periodo de seguimiento, 116 de los cuales correspondían al subgrupo de pacientes con

Determinação do teor de sílica em madeira por espectroscopia de absorção atômica de chama versus espectroscopia no ultravioleta-visível.

Directory of Open Access Journals (Sweden)

Laécio Carneiro Rodrigues

2009-10-01

Full Text Available Normal 0 21 MicrosoftInternetExplorer4 O presente trabalho teve como objetivo comparar o desempenho de duas técnicas analíticas, espectroscopia de absorção atômica de chama (FAAS e espectroscopia no ultravioleta-visível (UV-VIS, na determinação do teor de sílica em materiais lignocelulósicos. Os métodos foram testados em amostras de madeira de três árvores de Apuleia leiocarpa (Vog. Macbride. Os resultados mostraram que ambas as técnicas apresentam bons resultados, no entanto, a FAAS apresenta melhor precisão, rapidez e simplicidade operacional. Entretanto, a aplicação da espectroscopia UV-VIS é justificada pelo fato de os custos de aquisição e manutenção de um espectrofotômetro UV-VIS serem muito inferiores àqueles de um espectrômetro de absorção atômica. O uso da técnica FAAS deve ser preferido apenas quando os teores de sílica a serem determinados forem muito baixos, tendo em vista que a espectroscopia UV-VIS, nesses casos, não apresenta boa precisão.

Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model.

Science.gov (United States)

Kurundkar, Deepali; Srivastava, Ritesh K; Chaudhary, Sandeep C; Ballestas, Mary E; Kopelovich, Levy; Elmets, Craig A; Athar, Mohammad

2013-01-15

Histone deacetylase (HDAC) inhibitors are potent anticancer agents and show efficacy against various human neoplasms. Vorinostat is a potent HDAC inhibitor and has shown potential to inhibit growth of human xenograft tumors. However, its effect on the growth of skin neoplasm remains undefined. In this study, we show that vorinostat (2 μM) reduced expression of HDAC1, 2, 3, and 7 in epidermoid carcinoma A431 cells. Consistently, it increased acetylation of histone H3 and p53. Vorinostat (100mg/kg body weight, IP) treatment reduced human xenograft tumor growth in highly immunosuppressed nu/nu mice. Histologically, the vorinostat-treated tumor showed features of well-differentiation with large necrotic areas. Based on proliferating cell nuclear antigen (PCNA) staining and expression of cyclins D1, D2, E, and A, vorinostat seems to impair proliferation by down-regulating the expression of these proteins. However, it also induced apoptosis. The mechanism by which vorinostat blocks proliferation and makes tumor cells prone to apoptosis, involved inhibition of mTOR signaling which was accompanied by reduction in cell survival AKT and extracellular-signal regulated kinase (ERK) signaling pathways. Our data provide a novel mechanism-based therapeutic intervention for cutaneous squamous cell carcinoma (SCC). Vorinostat may be utilized to cure skin neoplasms in organ transplant recipient (OTR). These patients have high morbidity and surgical removal of these lesions which frequently develop in these patients, is difficult. Copyright © 2012 Elsevier Inc. All rights reserved.

Designed Synthesis of Nanostructured Magnetic Hydroxyapatite Based Drug Nanocarrier for Anti-Cancer Drug Delivery toward the Treatment of Human Epidermoid Carcinoma

Directory of Open Access Journals (Sweden)

Bharath Govindan

2017-06-01

Full Text Available Superparamagnetic Fe3O4 nanoparticles on hydroxyapatite nanorod based nanostructures (Fe3O4/HAp were synthesized using hydrothermal techniques at 180 °C for 12 h and were used as drug delivery nanocarriers for cancer cell therapeutic applications. The synthesized Fe3O4/HAp nanocomposites were characterized by X-ray diffraction analysis (XRD, Field emission scanning electron microscopy (FESEM, Fourier transform infrared spectroscopy (FTIR, Brunauer-Emmett-Teller (BET-analysis, and vibrating sample magnetometry (VSM. The morphologies of the Fe3O4/HAp nanocomposites show 15 nm Fe3O4 nanoparticles dispersed in the form of rods. The BET result shows that the synthesized samples have a high specific surface area of 80 m2 g−1 with mesoporous structures. Magnetic measurements revealed that the sample has high saturation magnetization of 18 emu/g with low coercivity. The Fe3O4/HAp nanocomposites had a large specific surface area (SSA, high mesoporous volume, and good magnetic property, which made it a suitable nanocarrier for targeted drug delivery systems. The chemotherapeutic agent, andrographolide, was used to investigate the drug delivery behavior of the Fe3O4/HAp nanocomposites. The human epidermoid skin cancer cells (A431 were used as the model targeting cell lines by treating with andrographolide loaded Fe3O4/HAp nanosystems and were further evaluated for their antiproliferative activities and the induction of apoptosis. Also, the present nanocomposite shows better biocompatibility, therefore it can be used as suitable drug vehicle for cancer therapy applications.

Flurbiprofen benzyl nitrate (NBS-242) inhibits the growth of A-431 human epidermoid carcinoma cells and targets β-catenin.

Science.gov (United States)

Nath, Niharika; Liu, Xiaoping; Jacobs, Lloydine; Kashfi, Khosrow

2013-01-01

The Wnt/β-catenin/T cell factor (TCF) signaling pathway is important in the development of nonmelanoma skin cancers (NMSCs). Nitric-oxide-releasing nonsteroidal anti-inflammatory drugs (NO-NSAIDs) are chemopreventive agents consisting of a traditional NSAID attached to an NO-releasing moiety through a chemical spacer. Previously we showed that an aromatic spacer enhanced the potency of a particular NO-NSAID compared to an aliphatic spacer. We synthesized an NO-releasing NSAID with an aromatic spacer (flurbiprofen benzyl nitrate, NBS-242), and using the human skin cancer cell line A-431, we evaluated its effects on cell kinetics, Wnt/β-catenin, cyclin D1, and caspase-3. NBS-242 inhibited the growth of A-431 cancer cells, being ~15-fold more potent than flurbiprofen and up to 5-fold more potent than NO-flurbiprofen with an aliphatic spacer, the half maximal inhibitory concentrations (IC50) for growth inhibition being 60 ± 4 μM, 320 ± 20 μM, and 880 ± 65 μM for NBS-242, NO-flurbiprofen, and flurbiprofen, respectively. This effect was associated with inhibition of proliferation, accumulation of cells in the G0/G1 phase of the cell cycle, and an increase in apoptotic cell population. NBS-242 cleaved β-catenin both in the cytoplasm and the nucleus of A-431 cells. NBS-242 activated caspase-3 whose activation was reflected in the cleavage of procaspase-3. To test the functional consequence of β-catenin cleavage, we determined the expression of cyclin D1, a Wnt-response gene. NBS-242 reduced cyclin D1 levels in a concentration dependent manner. These findings establish a strong inhibitory effect of NBS-242 in A-431 human epidermoid carcinoma cells. NBS-242 modulates parameters that are important in determining cellular mass.

VALIDACIÓN DE UNA METODOLOGÍA PARA LA DETERMINACIÓN DE CARBOFURAN EN SUELOS MEDIANTE CROMATOGRAFÍA LÍQUIDA DE ALTA EFICIENCIA CON DETECCIÓN ULTRAVIOLETA (CLAR-UV

Directory of Open Access Journals (Sweden)

Yenny Valencia

2011-01-01

Full Text Available Se validó una metodología analítica que permite cuantificar residuos de carbofuran en muestras de suelo. La extracción del plaguicida desde la matriz se realizó mediante agitación mecánica empleando acetato de etilo como solvente, los extractos obtenidos se sometieron a extracción en fase sólida (EFS utilizando cartuchos C18, finalmente, la determinación y cuantificación del carbofuran se llevó a cabo mediante cromatografía líquida de alta eficiencia con detección ultravioleta (CLAR-UV a una longitud de onda de 205 nm. La metodología validada es específica y selectiva para el carbofuran, lineal en el rango desde 0,47 hasta 2,36 mgKg-1, precisa con un coeficiente de variación típico (CVtip de 10,78%; exacta brindando un porcentaje de recuperación para la metodología global (porcentaje de R equivalente a 98,25±3,97% y sensible con límites de detección y cuantificación de 0,045 y 0,149 mgKg-1, respectivamente. También se verificó la robustez del método. Se analizaron dos muestras de suelo dedicados al cultivo de café, y se encontraron residuos de carbofuran durante los primeros 30 días después de su aplicación.

High ultraviolet index (UVI in two cities of Antioquia (Colombia Altos índices de radiación ultravioleta en Medellín y en una localidad del oriente antioqueño (Colombia

Directory of Open Access Journals (Sweden)

German Eduardo Hernández Garzón

2010-05-01

0cm 0pt; mso-layout-grid-align: none;"> 

Discussion and conclusions: This particular population appeared to be exposed to high levels of UV Radiation (UVR all year round. The use of the UVI may be a useful educative tool for the community in regards to the health risks of overexposure to UVR.

Introducción: la incidencia mundial de cáncer de piel se ha incrementado en las últimas dos décadas.

La exposición acumulada o crónica a la radiación ultravioleta es uno de los factores de riesgo más importantes para el desarrollo de melanoma, cáncer no-melanoma y cataratas. El índice ultravioleta (IUV ha sido diseñado para proveer información al público con el fin de inducir un comportamiento de protección hacia el sol.

Construction of the Tangent to a Cycloid Proposed by Wallis and Fermat

Directory of Open Access Journals (Sweden)

Loredana Biacino

2017-02-01

Full Text Available In this paper some methods used in the XVII century for the construction of the tangents to a cycloid in a point are exposed: the kinematical method employed by Roberval, the classical geometrical  method used by Wallis and the Fermat’s construction as a consequence of his tangents method. Le Costruzioni della Tangente alla Cicloide Proposte da Wallis e da Fermat In questo lavoro sono esposti vari metodi in uso nel ‘600 per la costruzione della tangente ad una cicloide in un suo punto: il metodo cinematico impiegato da Roberval, il metodo geometrico classico usato dal Wallis e la costruzione di Fermat come conseguenza del suo metodo delle tangenti. Parole Chiave: Cicloide, Tangente ad una curva, Metodo cinematico delle tangenti, Metodo delle tangenti di Fermat.

Some Non-Destructive Testing Methods Applicable to Sintered Materials; Quelques Methodes d'Essais Non Destructifs Applicables aux Materiaux Frittes; Nekotorye metody nedestruktivnykh ispytanii, primenimye k spechennym materialam; Algunos Metodos de Ensayo No Destructivo Aplicables a los Materiales Sinterizados

Energy Technology Data Exchange (ETDEWEB)

Labusca, Elena; Mirion, I.; Andreescu, N.; Alecu, M.; Biscoveanu, I. [Institut de Physique Atomique, Bucarest (Romania)

1965-10-15

solides frittes, a l'aide de la metallographie et de la microscopie electronique. Ces methodes mettent en evidence l'homogeneite de la structure, les dimensions et l'orientation des grains, la presence de defauts divers (inclusions, pores) et revolution meme du processus de frittage, y compris la formation des cristaux, la croissance granulaire, etc. Dans quelques cas, on peut combiner l'examen microscopique a des essais de microdurete. Cet examen de la structure microcristalline represente l'une des methodes principales de controle qualitatif des materiaux frittes, et ne peut etre remplace par aucun autre moyen d'investigation. 2. Controle du degre de consolidation, qui determine essentiellement la qualite des materiaux frittes. Ce controle est effectue par la mesure de quelques proprietes, telles que la conductibilite electrique et thermique, en correlation avec la densite, etant donne que la conductibilite des materiaux frittes est directement porportionnelle au degre de frittage. On a essaye aussi une methode adequate de controle de la porosite; on a obtenu des donnees experimentales interessantes, surtout au point de vue de la porosite libre, laquelle est susceptible aux inclusions gazeuses. Le memoire contient des donnees experimentales concernant l'application de ces methodes de controle a quelques materiaux frittes interessants pour la technologie nucleaire. (author) [Spanish] Teniendo en cuenta la estructura granular especifica de los materiales sinterizados, elaborados a partir de polvos, cuyo proceso de consolidacion se desarrolla en funcion del tratamiento de sinterizacion, los autores han estudiado algunos metodos para verificar el grado de sinterizacion y controlar ciertas propiedades. Entre los metodos no destructivos utilizados, se mencionan en la presente memoria: 1. Examen de la estructura cristalina de los solidos sinterizados por metalografia y microscopfa electronica. Estos metodos ponen de manifiesto el giado de homogeneidad estructural, la dimension

Triple pathological findings in a surgically amenable patient with mesial temporal lobe epilepsy

Directory of Open Access Journals (Sweden)

Fumin Tong

2015-01-01

Full Text Available Mesial temporal sclerosis (MTS is a well-recognized cause of intractable epilepsy; however, coexistence with focal cortical dysplasia (FCD is less common. Middle fossa epidermoid cysts are rare and may involve the temporal lobe. Most epidermoids are clinically silent, slow-growing, and seldom associated with overt symptomatology, including seizures. We describe a patient with multiple comorbidities including left MTS and a large epidermoid cyst involving the left quadrigeminal plate cistern compressing upon the cerebellar vermis and tail of the left hippocampus, resulting in refractory left temporal lobe epilepsy. The patient underwent left anterior temporal lobectomy. The surgical pathology demonstrated a third pathological finding of left temporal FCD type Ia. The patient has been seizure-free since the surgery. This case provides additional information with regard to the understanding of epileptogenicity and surgical planning in patients with MTS and epidermoid cysts.

Uses and updating of the Benders method in the integer-mixed programming in the planning of the electric power systems expansion; Usos y actualizacion del metodo de Benders en la programacion entera-mixta y en la planeacion de la expansion de los sistemas electricos de potencia

Energy Technology Data Exchange (ETDEWEB)

De la Torre Vega, Eli

1997-04-01

of some potential improvements that the proposed method has. [Espanol] En el primer capitulo se presenta la deduccion de los cortes de Benders partiendo de las propiedades de la dualidad. Tambien se presentan las propiedades de los cortes de Benders asi como el algoritmo inicial de Benders para resolver cualquier problema de programacion lineal entera-mixta. En el segundo capitulo, se presenta el problema de la planeacion de la expansion de los medios de generacion y transmision en un sistema electrico de potencia, las distintas estructuras de la programacion matematica a que da lugar y como se puede adaptar el metodo de Benders a estas. En el tercer capitulo se presentan las aportaciones teoricas de este trabajo: a) Como inicializar el problema maestro para aprovechar la experiencia adquirida despues de haber resuelto un problema similar, de modo que se pueda resolver mas eficientemente, la sucesion de problemas de programacion lineal entero-mixtos que surgen al resolver el problema de la planeacion de la expansion de los medios de generacion y transmision en un sistema electrico de potencia. b) Como generar un problema maestro cuya solucion optima continua corresponda al optimo continuo del problema entero-mixto, de modo que la busqueda de soluciones enteras se realice en la vecindad del optimo continuo. c) Como generar una solucion entera, cercana al optimo continuo del problema entero-mixto, que tenga mucha probabilidad de ser factible, y que quizas sea la solucion optima entera, en un tiempo menor al que se requiere para resolverlo en forma exacta. Ademas, se presentan otras ideas que se le pueden incorporar al metodo de Benders. A fin de mostrar la efectividad de las ideas propuestas, en el capitulo 4 se presentan los resultados obtenidos al resolver varios problemas usando: 1. El metodo de Benders in actualizacion, 2. El metodo de Ramificacion y Acotamiento, 3. La actualizacion de Benders al agregar restricciones y 4. La actualizacion de Benders al considerar

Progress of research on corneal collagen cross-linking for corneal melting

Directory of Open Access Journals (Sweden)

Ke-Ren Xiao

2016-06-01

Full Text Available Corneal collagen cross-linking(CXLcould increase the mechanical strength, biological stability and halt ectasia progression due to covalent bond formed by photochemical reaction between ultraviolet-A and emulsion of riboflavin between collagen fibers in corneal stroma. Corneal melting is an autoimmune related noninfectious corneal ulcer. The mechanism of corneal melting, major treatment, the basic fundamental of ultraviolet-A riboflavin induced CXL and the clinical researches status and experiment in CXL were summarized in the study.

Development of an analytic method for arsenic's determination in lime and tortilla; Desarrollo de un metodo analitico para determinacion de arsenico en cal y tortilla

Energy Technology Data Exchange (ETDEWEB)

Huato Soberanis, Julio; Ogura, Tetsuya [Universidad Autonoma de Guadalajara, Guadalajara, Jalisco (Mexico)

1995-02-01

A spectrophotometric method to determine As in tortilla and lime has been optimized, modifying the AsH{sub 3} generator. The reaction between arsin (AsH{sub 3}){sub 4} and diethyldithiocarbamate of Ag (AgDDC); was followed spectrophotometrically. The conditions under which the As remains in the ash during the calcination of the tortillas were studied. It was found that when they were heated in a quartz tube with a careful control of the air flow and oxygen, as well as the heating temperature, the arsenic loss in minimized. [Spanish] Se ha optimizado el metodo para determinar As en la tortilla y cal mediante espectrometria en el visible del color producido en la reaccion entre Arsina (AsH{sub 3}){sub 4} y dietilditiocarbamato de plata (AgDDC); modificando el generador de AsH{sub 3}. Se han buscado las condiciones en las que el arsenico permanece en las cenizas de la calcinacion de las tortillas; encontrandose que las tortillas deben calentarse en un tubo de cuarzo con control del flujo de aire y oxigeno asi como de la temperatura de calentamiento.

Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model

Energy Technology Data Exchange (ETDEWEB)

Kurundkar, Deepali; Srivastava, Ritesh K.; Chaudhary, Sandeep C. [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States); Ballestas, Mary E. [Department of Pediatrics Infectious Disease, Children' s of Alabama, School of Medicine, University of Alabama at Birmingham, AL (United States); Kopelovich, Levy [Division of Cancer Prevention, National Cancer Institute, 6130 Executive Blvd., Suite 2114, Bethesda, MD 20892 (United States); Elmets, Craig A. [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States); Athar, Mohammad, E-mail: mathar@uab.edu [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States)

2013-01-15

Histone deacetylase (HDAC) inhibitors are potent anticancer agents and show efficacy against various human neoplasms. Vorinostat is a potent HDAC inhibitor and has shown potential to inhibit growth of human xenograft tumors. However, its effect on the growth of skin neoplasm remains undefined. In this study, we show that vorinostat (2 μM) reduced expression of HDAC1, 2, 3, and 7 in epidermoid carcinoma A431 cells. Consistently, it increased acetylation of histone H3 and p53. Vorinostat (100 mg/kg body weight, IP) treatment reduced human xenograft tumor growth in highly immunosuppressed nu/nu mice. Histologically, the vorinostat-treated tumor showed features of well-differentiation with large necrotic areas. Based on proliferating cell nuclear antigen (PCNA) staining and expression of cyclins D1, D2, E, and A, vorinostat seems to impair proliferation by down-regulating the expression of these proteins. However, it also induced apoptosis. The mechanism by which vorinostat blocks proliferation and makes tumor cells prone to apoptosis, involved inhibition of mTOR signaling which was accompanied by reduction in cell survival AKT and extracellular-signal regulated kinase (ERK) signaling pathways. Our data provide a novel mechanism-based therapeutic intervention for cutaneous squamous cell carcinoma (SCC). Vorinostat may be utilized to cure skin neoplasms in organ transplant recipient (OTR). These patients have high morbidity and surgical removal of these lesions which frequently develop in these patients, is difficult. -- Highlights: ► Vorinostat reduces SCC growth in a xenograft murine model. ► Vorinostat dampens proliferation and induces apoptosis in tumor cells. ► Diminution in mTOR, Akt and ERK signaling underlies inhibition in proliferation. ► Vorinostat by inhibiting HDACs inhibits epithelial–mesenchymal transition.

Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model

International Nuclear Information System (INIS)

Kurundkar, Deepali; Srivastava, Ritesh K.; Chaudhary, Sandeep C.; Ballestas, Mary E.; Kopelovich, Levy; Elmets, Craig A.; Athar, Mohammad

2013-01-01

Histone deacetylase (HDAC) inhibitors are potent anticancer agents and show efficacy against various human neoplasms. Vorinostat is a potent HDAC inhibitor and has shown potential to inhibit growth of human xenograft tumors. However, its effect on the growth of skin neoplasm remains undefined. In this study, we show that vorinostat (2 μM) reduced expression of HDAC1, 2, 3, and 7 in epidermoid carcinoma A431 cells. Consistently, it increased acetylation of histone H3 and p53. Vorinostat (100 mg/kg body weight, IP) treatment reduced human xenograft tumor growth in highly immunosuppressed nu/nu mice. Histologically, the vorinostat-treated tumor showed features of well-differentiation with large necrotic areas. Based on proliferating cell nuclear antigen (PCNA) staining and expression of cyclins D1, D2, E, and A, vorinostat seems to impair proliferation by down-regulating the expression of these proteins. However, it also induced apoptosis. The mechanism by which vorinostat blocks proliferation and makes tumor cells prone to apoptosis, involved inhibition of mTOR signaling which was accompanied by reduction in cell survival AKT and extracellular-signal regulated kinase (ERK) signaling pathways. Our data provide a novel mechanism-based therapeutic intervention for cutaneous squamous cell carcinoma (SCC). Vorinostat may be utilized to cure skin neoplasms in organ transplant recipient (OTR). These patients have high morbidity and surgical removal of these lesions which frequently develop in these patients, is difficult. -- Highlights: ► Vorinostat reduces SCC growth in a xenograft murine model. ► Vorinostat dampens proliferation and induces apoptosis in tumor cells. ► Diminution in mTOR, Akt and ERK signaling underlies inhibition in proliferation. ► Vorinostat by inhibiting HDACs inhibits epithelial–mesenchymal transition.

Epidermoid carcinomas of the anal canal treated with definitive radiation therapy in a series of 305 patients; Carcinomes epidermoides du canal anal traites par irradiation a visee curative: a propos de 305 patients

Energy Technology Data Exchange (ETDEWEB)

Deniaud-Alexandre, E.; Touboul, E.; Huang, R.; Qu, S.H.; Pene, F.; Schlienger, M. [Hopital Tenon, Service d' Oncologie-Radiotherapie, 75 - Paris (France); Tiret, E.; Parc, R. [Hopital Saint-Antoine, Service de Chirurgie Digestive, 75 - Paris (France); Sezeur, A. [Hopital des Diaconesses, Service de Chirurgie Generale, 75 - Paris (France); Houry, S. [Hopital Tenon AP-HP, Service de Chirurgie Digestive, 75 - Paris (France); Gallot, D. [Groupe Hospitalier Bichat-Claude-Bernard, Service de Chirurgie Generale et Digestive B, 75 - Paris (France)

2003-08-01

Purpose. - To identify prognostic factors and treatment toxicity in a series of epidermoid cancers of the anal canal without evident metastasis. Patients and methods. - Between June 1972 and January 1997, 305 patients (pts) were treated with curative-intent radiation therapy (RT). The T-stages according to the 1987 UICC classification were: 26 T1, 141 T2, 104 T3, and 34 T4. There were 49 pts with nodal involvement at presentation. Pretreatment anal function scoring according to our in-house system was: 22 scored 0, 182 scored 1, 74 scored 2, 7 scored 3. 11 scored 4, and 9 not available pts. The treatment started with external beam RT (EBRT) in 303 pts (median dose: 45 Gy). After a rest period of 4 to 6 weeks, a boost of 20 Gy was delivered by EBRT in 279 pts and by interstitial {sup 192}Ir brachytherapy (Bcy) in 17 pts. Seven pts received only one course of EBRT (mean dose: 49.5 Gy) and 2 pts were treated with interstitial {sup 192}Ir Bcy alone (55 and 60 Gy, respectively). concomitant chemotherapy (5-fluoro-uracil and either mitomycin C or cisplatin) was delivered to 19 pts. Mean follow-up was 103 months. Results. - At the end of RT local tumor clinical complete response (cCR) rate was 80%. Out of 61 non responders or local progressive tumors 27 (44%) were salvaged with abdomino-perineal resection (APR). The rate of local tumor relapse (LR) was 12%. Out of 37 LTR, 20 (54%) were salvaged with APR and one with interstitial {sup 192}Ir Bcy. The overall local tumor control (LC) rate with or without salvage local treatment was 84%. LC rate with a good anal function scoring (score 0 and 1) was 56.5%0. Among 181/186 available pts who preserved their anus, 94% had a good anal function scoring. For a subgroup of 15 pts with length tumor <2 cm-N0, the LC rate after the end of RT was 100% the LC rate with or without local salvage treatment was 100%, and among 13 available pts who preserved their anus, the anal function scoring was good in 12 pts (92%). The 10-years disease

Case report

African Journals Online (AJOL)

abp

2014-07-27

Jul 27, 2014 ... It was a pearly tumor. The histological examination confirms the epidermoid cyst. Discussion. The Epidermoid cyst is a rare and slow growing brain tumor. It represents approximately 1% of all intracranial tumors. This lesion is known to be often located in the Cerebellopontine angle whereas dermoid cyst ...

A Portable Parallel Implementation of the U.S. Navy Layered Ocean Model

Science.gov (United States)

1995-01-01

Wallcraft, PhD (I.C. 1981) Planning Systems Inc. & P. R. Moore, PhD (Camb. 1971) IC Dept. Math. DR Moore 1° Encontro de Metodos Numericos...Kendall Square, Hypercube, D R Moore 1 ° Encontro de Metodos Numericos para Equacöes de Derivadas Parciais A. J. Wallcraft IC Mathematics...chips: Chips Machine DEC Alpha CrayT3D/E SUN Sparc Fujitsu AP1000 Intel 860 Paragon D R Moore 1° Encontro de Metodos Numericos para Equacöes

Efeitos da radiação ultravioleta-B sobre a morfologia foliar de Arabidopsis thaliana (L. Heynh. (Brassicaceae Effects of ultraviolet-B radiation on leaf morphology of Arabidopsis thaliana (L. Heynh. (Brassicaceae

Directory of Open Access Journals (Sweden)

Maria Regina Torres Boeger

2006-06-01

Full Text Available A redução da camada de ozônio resulta no aumento da radiação ultravioleta que atinge a superfície terrestre, especialmente a radiação ultravioletaB (UV-B. O aumento da radiação poderá induzir a mudanças estruturais e fisiológicas nas plantas, influenciando no seu crescimento e desenvolvimento. O objetivo deste trabalho foi determinar os efeitos da radiação UV-B ambiente sobre a morfologia das folhas de Arabidopsis thaliana desenvolvidas em condições controladas. As sementes de A. thaliana cresceram em câmaras de crescimento, com 300 µmol m-2s-1 de radiação fotossinteticamente ativa (PAR com ou sem 6 kJ m-2 s-1 de radiação UV-Bbe (UV-Bbe; UV-B biologicamente efetiva. Após 21 dias, 10 folhas de cada tratamento (com e sem radiação UV-B foram coletadas para avaliar área foliar, massa fresca e seca, AEF, densidades estomáticas e de tricomas de ambas as faces da folha, espessura da lâmina foliar e concentração de compostos fenólicos e de clorofila total, a e b. As folhas tratadas com radiação UV-B apresentaram menor área foliar, massa fresca e seca, densidade de tricomas na face adaxial e densidade de estômatos na face abaxial da folha. Entretanto, apresentaram os maiores valores médios de espessura total da lâmina e do mesofilo, maior concentração de clorofila total, clorofila a e clorofila b e compostos fenólicos foliares do que as folhas não tratadas com radiação UV-B. Essas diferenças morfológicas significativas (p Reduction of the ozone layer results in the increase in ultraviolet radiation reaching the earth's surface, especially the ultraviolet-B (UV-B. The increase of radiation may induce structural and physiological changes in plants, influencing their growth and development. This paper evaluates the effects of ambient UV-B radiation upon to the leaf morphology of Arabidopsis thaliana developed under controlled conditions. The seeds of A. thaliana grown in environmental chamber, with 300 µmol m-2

Clinical Investigation Program: Annual Progress Report

Science.gov (United States)

1992-09-30

Diamminedichloroplatinum (II), Methotrexate and Bleomycin in the Treatment of Advanced Epidermoid Carcinoma of the Penis , Phase II...II), Methotrexate and Bleomycin in the Treatment of Advanced Epidermoid Carcinoma of the Penis , Phase II (5) Start Date: (6) Est Compl Date: (7...Associate Investigators (11) Key Words: constitutional delay delayed puberty (12) Accumulative MEDCASE:* (13) Est Accum OKA Cost:* *Refer to Unit Summary

Non-Destructive Methods for Determining Burn-Up in Nuclear Fuel; Methodes Non Destructives d'Evaluation du Taux de Combustion dans le Combustible Nucleaire; Metody opredeleniya vygoraniya v yadernom toplive bez razrusheniya obraztsa; Metodos No Destructivos para Determinai el Grado de Combustion de los Elementos Combustibles Nucleares

Energy Technology Data Exchange (ETDEWEB)

McGonnagle, W. J. [Illinois Institute of Technology, Chicago, IL (United States)

1966-02-15

gamma emis par les matieres radioactives qui se forment au cours du processus de fission, en particulier le spectrometre a cristal courbe, le spectrometre Compton magnetique, le spectrometre Compton a coiencidence et le spectrometre a scintillation. Parmi les autres methodes non destructives, on peut citer l'activation de feuilles, la transmission des neutrons, l'analyse par activation, la mesure des rayonnements gamma de capture et la mesure des neutrons instantanes et differes. Le memoire etudie les principes essentiels des differents appareils et procedes ci-dessus, leur precision et leurs limitations. Le memoire presente des methodes non destructives utilisant les isotopes stables produits au cours du processus de fission. Dans les mesures au moyen de ces isotopes, le schema d'irradiation n'a qu'une importance secondaire et le temps de refroidissement ne joue aucun role. De plus, on dispose de donnees nucleaires plus precises sur les produits stables de la fission. Il semble que les plus utiles de tous les isotopes stables produits au cours du processus de fission soient ceux du zirconium, du molybdene, du ruthenium et du neodyme. Le memoire etudie l'interet de ces methodes d'analyse non destructive. (author) [Spanish] Los metodos no destructivos son de gran utilidad para medir cuantitativamente el grado de combustion. El metodo ideal seria el que no requiriese datos especiales sobre los espectros neutrtfni- cos, las irradiaciones precedentes o el tiempo de enfriamiento. Los elementos combustibles irradiados llevan en cierto modo el registro de su grado de combustion. Este registro consiste en el conjunto de los isotopos radiactivos y estables resultantes del proceso de fision. Desgraciadamente, tanto con los metodos no destructivos como con los destructivos el espectro neutronico, las irradiaciones precedentes y el tiempo de enfriamiento influyen sobre dicho registro. Analogamente, la falta de datos nucleares precisos tales como las secciones eficaces nucleares

Control Methods Used in the Department of Metallurgy for Structure and Fuel Elements; Methodes de Controle Utilisees au Departement de Metallurgie pour les Elements de Structure et les Elements Combustibles; Metody kontrolya struktury toplivnykh ehlementov v departamente metallurgii; Metodos de Control Utilizados en el Departamento de Metalurgia para los Elementos Estructurales y Combustibles

Energy Technology Data Exchange (ETDEWEB)

Destribats, Marie-Therese; Allain, C.; Prot, A.; Thome, P. [Centre d' Etudes Nucleaires de Saclay (France)

1965-09-15

reactores indujeron a utilizar y a perfeccionar numersos metodos no destructivos destinados a inspeccionar los distintos materiales que intervienen en la construccion de esos reactores; en particular radiografia y gamma- grafia, metodos ultrasonicos y empleo de corrientes de Foucault.. A continuacion se enumeran las operaciones de control llevadas a cabo durante la construccion de reactores pertenecientes a las familias EdF (grafito-gas) y EL 4 (agua pesada), y de elementos colaminados; se hace hincapie en ciertos aspectos caracteristicos de estos metodos, algunos de los cuales son ya bien conocidos. Familia EdF: metodos ultrasonicos para medir el espesor de las paredes de tubos de uranio o aleacion de uranio ; localizacion de las cavidades en esos tubos por gammagraffa; empleo de medios ultrasonicos para control de los tratamientos termicos a que se someten los tubos; empleo de procedimientos ultrasonicos para buscar fallas (inclusiones, grietas) en las palanquillas y barras con que se elaboran las vainas de Mg-Zr; control de la estanqueidad de los elementos mediante exudacion de helio. EL4: uso de metodos ultrasonicos y corrientes de Foucault para medir espesores de pared en tubos de Zircaloy, sean de fuerza o de guia; empleo de metodos ultrasonicos para inspeccionar tubos de fuerza de Zircaloy y vainas de acero inoxidable; radiografia al vacio de vainas de Be; control de la estanqueidad de barras huecas mediante exudacion de helio. Elementos colimados: medida del espesor de vainas mediante el empleo de corrientes de Foucault pulsadas; verificacion de la posicion del alma en tubos y placas mediante radiografia, recuento gamma y aplicacion de corrientes de Foucault pulsadas; control de la homogeneidad del combustible por recuento gamma; deteccion de defectos en barras de Zr-U mediante procedimientos ultrasonicos y gammagraficos; determinacion de las zonas despegadas en placas, empleando metodos ultrasonicos, corrientes de Foucault pulsadas y medicion de resistividad. Estos

Flurbiprofen benzyl nitrate (NBS-242 inhibits the growth of A-431 human epidermoid carcinoma cells and targets ß-catenin

Directory of Open Access Journals (Sweden)

Nath N

2013-05-01

in a concentration dependent manner. Conclusion: These findings establish a strong inhibitory effect of NBS-242 in A-431 human epidermoid carcinoma cells. NBS-242 modulates parameters that are important in determining cellular mass. Keywords: flurbiprofen, nitric oxide, ß-catenin, chemoprevention, skin cancer

Estudo da fotodegradação de poliisoprenos naturais (borrachas naturais em radiações específicas do ultravioleta (UV - doi: 10.5102/ucs.v3i2.564

Directory of Open Access Journals (Sweden)

Kárin Astrid Marques dos Santos

2008-04-01

Full Text Available Filmes de poliisoprenos (PI naturais e sintéticos foram expostos à luz ultravioleta (UV e analisados por espectroscopia de absorção UV, antes e após exposição à radiação UV. Filmes de padrões cis PII foram irradiados separadamente por fontes de luz com comprimentos de ondas iguais a 253 e 300. A fotooxidação foi monitorada observando-se a dependência das intensidades das absorções correspondentes aos modos de estiramento C=C, C=O e O-H e do modo “wagging” =C-H de cis-e trans-PI em função do tempo de exposição. A irradiação em 253 nm levou a reações de reticulação do polímero, impedindo a completa oxidação do filme polimérico. Para irradiação em 300nm, as reações de cisão da cadeia ocorreram preferencialmente, levando à completa oxidação do filme polimérico. Os elastômeros de Hevea brasilienses (HB e Hancornia speciosa (HS foram caracterizadas por espectroscopia de absorção no infravermelho (FTIR como cis-1,4-poliisopreno. A foto-oxidação dos elastômeros apresentou cinética diferente com tempo de indução menor que o observado para os padrões cis-PI. A maior velocidade para o processo de fotodegradação dos filmes de BNs foi atribuída à presença de impurezas, caracterizadas por bandas de absorção nas regiões de estiramento O-H e C=O, mesmo antes da exposição à radiação UV.

The inguinal lymphadenectomy in the management of penile cancer in Costa Rica, the experience of a center between the years 2003 to 2012

International Nuclear Information System (INIS)

Vasquez Chaves, Laura Leticia

2013-01-01

The neoplasm of the penis has been a disease few frequent and without studies to indicate which is the reality of patients with epidermoid cell carcinoma of the penis that are subjected to inguinal lymphadenectomy. The results of this disease as regards the healing and complications derived from the surgical procedure are described by means of a retrospective design based on review of clinical records. The management of epidermoid cell carcinoma of the penis is analyzed to determine the characteristics of patients and the results of the inguinal lymphadenectomy between the year 2003 and the year 2012 in a hospital in Costa Rica. Men diagnosed with epidermoid cell carcinoma of the penis has been the population to which the study was performed after resection of the primary tumor [es

NMR imaging

International Nuclear Information System (INIS)

Ouchi, Toshihiro; Steiner, R.E.

1984-01-01

Three epidermoid and two dermoid tumours, pathologically proven, were examined by NMR and CT scans. Although most brain tumours have a low signal with a long T 1 , a dermoid cyst and one of the two components of the other dermoid tumour had a high signal and therefore a short T 1 . All three epidermoid tumours had a low signal and a long T 1 . Because of the high level contrast between some of the tumours and cerebrospinal fluid, NMR is helpful to detect the lesion. Neither of the liquid fluid levels in the tumour cysts or floating fat in the subarachnoid space was recognized in one patients, but the fine leakage of the content from the epidermoid cyst into the lateral ventricle was detected on a saturation recovery 1000 image in one case. (author)

Simulation of molecular transitions using classical trajectories

Energy Technology Data Exchange (ETDEWEB)

Donoso, A.; Martens, C. C. [University of California, California (United States)

2001-03-01

In the present work, we describe the implementation of a semiclassical method to study physical-chemical processes in molecular systems where electronic state transitions and quantum coherence play a dominant role. The method is based on classical trajectory propagation on the underlying coupled electronic surfaces and is derived from the semiclassical limit of the quantum Liouville equation. Unlike previous classical trajectory-based methods, quantum electronic coherence are treated naturally within this approach as complex weighted trajectory ensembles propagating on the average electronic surfaces. The method is tested on a model problem consisting of one-dimensional motion on two crossing electronic surfaces. Excellent agreement is obtained when compared to the exact results obtained by wave packet propagation. The method is applied to model quantum wave packet interferometry, where two wave packets, differing only in a relative phase, collide in the region where the two electronic surfaces cross. The dependence of the resulting population transfer on the initial relative phase of the wave packets is perfectly captured by our classical trajectory method. Comparison with an alternative method, surface hopping, shows that our approach is appropriate for modelling quantum interference phenomena. [Spanish] En este trabajo se describe la implementacion de un metodo semiclasico para estudiar procesos fisicos-quimicos en sistemas moleculares donde las transiciones entre estados electronicos y las coherencias cuanticas juegan un papel predominante. El metodo se basa en la propagacion de trayectorias clasicas sobre las correspondientes superficies electronicas acopladas y se deriva a partir del limite semiclasico de la ecuacion cuantica de Liouville. A diferencia de metodos previos basados en trayectoria clasica, dentro de este esquema, las coherencias electronicas cuanticas son tratadas de manera natural como ensamble de trayectorias con pesos complejos, moviendose en

Avaliação dos métodos de amostragem para fauna perifítica em macrófitas na Reserva da Biosfera, Serra do Espinhaço, Estado de Minas Gerais, Brasil - DOI: 10.4025/actascibiolsci.v30i3.377 Evaluation of sampling methods for periphytic fauna in macrophytes at the Espinhaço Mountain Range Biosphere Reserve, Minas Gerais State, Brazil - DOI: 10.4025/actascibiolsci.v30i3.377

Directory of Open Access Journals (Sweden)

Cristiane Machado López

2008-10-01

Full Text Available Os métodos “Jarra”, “Remocao Manual” e “Draga de Eckman modificada” foram avaliados para amostrar a fauna perifitica associada a macrofitas aquaticas. Foram coletadas 63 amostras em cinco ambientes lenticos e tres loticos na reserva da biosfera da Serra do Espinhaco (Estado de Minas Gerais, Brasil. Os testes estatisticos Anova e Tukey foram feitos para riqueza de Protista, Rotifera e Crustacea, enquanto para a abundancia de Protista, Rotifera, Crustacea, Gastrotricha, Tardigrada e Nematoda foram avaliados os percentuais. Os protozoarios e rotiferos representaram 80% da abundancia e riqueza da comunidade. Nos ecossistemas avaliados todos os metodos foram relevantes para Protista, por outro lado, o metodo da Jarra foi o mais adequado para a analise de Crustacea. Entre os metodos, a Draga foi menos indicada para os grupos de microinvertebrados nos ecossistemas aquaticos. Os metodos Remocao Manual e Draga foram apropriados para analisar Rotifera. A abundancia de Gastrotricha e Tardigrada demonstrou melhores resultados pelo metodo da Jarra e Nematoda pelo metodo da Draga. Os tres metodos sao apropriados para amostragem da fauna perifitica em ambos os sistemas aquaticos. Entretanto, e importante estar ciente de que para cada tipo de ecossistema a amostragem da comunidade faunistica requer um metodo especifico para obter a melhor performance.The methods “Jar”, “Manual Removal” and “modified Ekman`s Dredge” were evaluated for sampling periphyton fauna associated to aquatic macrophytes. Sixty three samples were collected from five lentic and three lotic water bodies at Espinhaço Mountain Range Biosphere Reserve (Minas Gerais, Brazil. ANOVA and Tukey statistical tests were performed for Protista, Rotifera and Crustacea richness, whilst Protista, Rotifera, Crustacea, Gastrotricha, Tardigrada and Nematoda, abundance were evaluate by percentage. Amongst the three methods, Dregde is less indicated for different water bodies systems

Comparative Study of the Methods Used for the Computer Resolution of Composite Gamma-Ray Spectra; Etude Comparative des Methodes Utilisees pour la Resolution de Spectres Gamma Complexes au Moyen d'un Ordinateur; Sravnitel'noe izuchenie metodov razresheniya sostavnykh gamma-spektrov pri pomoshchi schetno-reshayushchego ustrojstva; Estudio Comparativo de los Metodos Aplicados para Resolver Espectros Gamma Complejos Mediante Calculadoras

Energy Technology Data Exchange (ETDEWEB)

DeHaan, A. Jr.; Leventhal, L.; Benson, P. [Tracerlab, Richmond, CA (United States)

1965-10-15

'a resolution; 2. Resolution du pic sans elimination; 3. Etablissement d'un ensemble d'equ'ations lineaires simultanees du meme ordre que le nombre de radionucleides presents dans le melange et solution de ces equations; 4. Evaluation des concentrations non connues par la methode des moindres carres, classique ou ponderee; 5. Combinaison des methodes statistiques et des methodes des moindres carres utilisant la regression lineaire multiple progressive, en s'efforcant d'integrer des processus decisifs dans l'analyse. Pour chaque methode d'analyse appliquee a des melanges de radionucleides, les auteurs fournissent une estimation statistique des erreurs de mesure de la concentration des radionucleides. (author) [Spanish] La resolucion de mezclas complejas de emisores gamma se ha simplificado gracias al empleo de espectrometros gamma muy perfeccionados en asociacion con calculadoras numericas. En la actualidad, los laboratorios pueden en general disponer de estos instrumentos o tener facilmente acceso a ellos. En la memoria se examinan los metodos seguidos en el laboratorio de los autores para determinar la concentracion de cada radionuclido emisor gamma contenido en muestras de precipitaciones radiactivas, y se comparan los resultados obtenidos por los diferentes metodos matematicos aplicables a las muestras compuestas. Los datos proporcionados por las calculadoras se comparan con los resultados obtenidos por analisis radioquimico de la muestra. Se han analizado muestras binarias por los metodos mencionados, operacion que se extendio despues a las mezclas integradas por muchos componentes. Se ha elaborado un metodo de computo que normaliza los espectros gamma para reducir al mfnimo el efecto de la deriva del espectrometro a largo plazo, y representa el espectro segun un sistema de coordenadas, una de las cuales es la energia. Se han investigado los efectos de un 'fotopico imprevisto', de una componente de intensidad cero y de picos superpuestos en la resolucion segun los

Responsabilità giuridica e scienze sperimentali sul vivente

Directory of Open Access Journals (Sweden)

Patrick Nerhot

2017-12-01

Full Text Available SOMMARIO: 1. Il "vivente": inoperosità dei concetti della filosofia profana dei Lumi - 2. La ricerca-costruzione di una infinita-fine - 3. Le scienze "sperimentali" come la non distinzione tra "causa" e "effetto" - 4. La nuova questione di metodo posta al "vivente" - 5. La sfida di una etica come adeguazione tra etica e metodo.

Chemoradiation for adenocarcinoma of the anus

International Nuclear Information System (INIS)

Papagikos, Michael; Crane, Christopher H.; Skibber, John; Janjan, Nora A.; Feig, Barry; Rodriguez-Bigas, Miguel A.; Hung, Arthur; Wolff, Robert A.; Delclos, Marc; Lin, Edward; Cleary, Karen

2003-01-01

Purpose: To assess the efficacy and limitations of definitive chemoradiation for adenocarcinoma of the anal canal and to propose a treatment strategy that addresses the limitations of treatment. Methods and Materials: Between 1976 and 1998, 16 patients with localized adenocarcinoma of the anal canal were treated with radiotherapy with or without chemotherapy with curative intent. Available histologic slides were reviewed for evidence of primary adenocarcinoma of anal duct origin. The treatment results for these patients were compared with those of a group of patients with epidermoid histologic features who were all treated with definitive chemoradiation (55 Gy with concurrent 5-fluorouracil and cisplatin, n=92) between 1989 and 1998. The hospital records were reviewed for all patients. Patients with epidermoid carcinoma presented with more advanced primary tumors (42% vs. 19% Stage T3 or greater). All adenocarcinoma patients were treated with radiotherapy (median dose 55 Gy): 11 received concurrent 5-fluorouracil-based chemotherapy and 5 received radiotherapy alone. The initial surgical procedures included abdominoperineal resection, excisional biopsies (n=5), and local excision (n=1). Abdominoperineal resection was performed as salvage therapy after local recurrence in 5 patients. The Kaplan-Meier method was used to calculate 5-year actuarial pelvic control, distant disease control, disease-free survival, and overall survival. The median follow-up was 45 months (range 5-196) for patients with adenocarcinoma and 44 months (range 9-115) for patients with epidermoid histologic features. Results: Both local and distant recurrence rates were significantly greater in the adenocarcinoma patients. Of 16 patients with adenocarcinoma, 7 (5-year actuarial rate 54%) had recurrence at the primary site compared with 16 (5-year actuarial rate 18%) of 92 patients with epidermoid histologic features (p=0.004). Distant disease developed in more patients with adenocarcinoma (5-year

Decontamination pig carcasses of organic acids with commercial and saline acidified ultraviolet lightDescontaminação de cortes suínos com ácidos orgânicos comerciais, solução salina acidificada e luz ultravioleta

Directory of Open Access Journals (Sweden)

Eliane Maria De

2013-06-01

carne suína, foram realizados nove tratamentos com misturas de ácidos orgânicos, solução salina acidificada, exposição a luz ultravioleta e água a 80ºC, durante 30 dias de estocagem, de barriga suína, sendo todas as analises realizadas em triplicatas. Foram realizadas contagens de micro-organismos aeróbios mesófilos, psicrotróficos, coliformes totais e fecais, Salmonella, determinação do pH e do número de substâncias reativas ao ácido tiobarbitúrico (TBA avaliação sensorial. Evidenciou uma redução da contaminação dos cortes de barriga suína, com mistura de ácidos orgânicos, seguidos da exposição à luz ultravioleta por 1 minuto. Em relação ao pH os tratamentos em que foi adicionada a mistura de ácidos orgânicos apresentaram diferença dos demais tratamentos com exceção do controle. As soluções de ácidos orgânicos não alteraram as características sensoriais da carne suína assada. Através dos experimentos realizados neste estudo, concluiu-se que se pode estabelecer novas propostas como alternativa para a indústria cárnea obtendo um maior controle microbiológico sem alterar as características da matéria prima, aumentando a vida útil e desta forma oferecendo ao consumidor um produto de qualidade e comercialmente seguros.

A PATIENT WITH EPIDERMAL CYST IN MANDIBULA, SIMULTANEOUSLY ENUCLEATION OF EPIDERMAL CYST AND IMPLANT PLACEMENT:

OpenAIRE

Terzi, Mithat; Karaaslan, Fatih; Çalık, Muhammed; Dilsiz, Alparslan; Altun, Eren

2015-01-01

Dermoid cysts are malformations that rarely seen in oral mucosa and can be defined as an epidermoid when lining presents only epithelium. Epidermoid and dermoid cysts are rarely seen in intraosseous and there was a few report about their presentation in the jaws. The development in implant surfaces and surgical techniques has led to changes in treatment protocol such as immediate implant placement. Immediate implant placement has some advantages such as, reduction in the time of treat- ment a...

Involvement of growth factors and their receptors in radon-induced rat lung tumors

International Nuclear Information System (INIS)

Leung, F.C.; Dagle, G.E.; Cross, F.T.

1992-01-01

In this paper we examine the role of growth factors (GF) and their receptors (GFR) in radon-induced rat lung tumors. Inhalation exposure of radon and its daughters induced lung tumors in rats, but the molecule/cellular mechanisms are not known. Recent evidence suggests that GF/GFR play a critical role in the growth and development of lung cancer in humans and animals. We have developed immunocytochemical methods for identifying sites of production and action of GF/GFR at the cellular level; for example, the avidin-biotin horseradish peroxidase technique. In radon-induced rat epidermoid carcinomas, epidermal growth factor (EGF), EGF-receptors (EGF-R), transforming growth factor alpha (TGF-α), and bombesin were found to be abnormally expressed. These abnormal expressions, mainly associated with epidermoid carcinomas of the lung, were not found in any other lung tumor types. Our data suggest that EGF, EGF-R, TGF-α, and bombesin are involved in radon oncogenesis in rat lungs, especially in epidermoid carcinomas, possibly through the autocrine/paracrine pathway

Preparation of hydrotalcite compounds using ultrasound irradiation to capture CO{sub 2}; Preparacion de compuestos tipo hidrotalcita utilizando irradiacion de ultrasonido para la captura de CO{sub 2}

Energy Technology Data Exchange (ETDEWEB)

Martinez, J.A.J.; Paredes, S.P.; Valenzuela, M.A.; Hernandez, M.L. [Instituto Politecnico Nacional, ESIQIE, Mexico, D.F. (Mexico)]. E-mail: sparedesc@ipn.com.mx

2009-09-15

Al-Mg hydrotalcite compounds (HTC) were prepared using co-precipitation, sol-gel and reconstruction of the structure with ultrasound-assisted irradiation. The interlaminar components for each method were nitrate, acetylacetonate ethoxide and metavanadate, respectively. Optimization of the synthesis was performed using x-ray diffraction. The effect of the different parameters on synthesis was studied, including pH, time and ultrasound irradiation power. In addition, for the reconstruction method, temperature and calcination time were evaluated. For all methods, ultrasound-assisted methods were found to be more efficient and economical than conventional methods reported (autoclave). They also have the advantage of being able to control properties such as crystallinity, porosity and the specific surface, which significantly depends on the preparation method, irradiation time and type of interlaminar component. These methods are intended to synthesize interlaminar anionic materials that are very scarce in nature with better properties than traditional adsorbents used for the capture of CO{sub 2}. [Spanish] Se prepararon compuestos tipo hidrotalcita Al-Mg por los metodos de: coprecipitacion, sol gel y reconstruccion de la estructura asistidos por irradiacion de ultrasonido. Los componentes interlaminares para cada metodo fueron respectivamente: nitrato, etoxido-acetilacetonato y metavanadato. La optimizacion de la sintesis, se efectuo mediante difraccion de rayos-X. Se estudio el efecto de diversos parametros en la sintesis: pH, tiempo y potencia de irradiacion de ultrasonido, ademas, para el metodo de reconstruccion se evaluaron la temperatura y el tiempo de calcinacion. En todos los casos se encontro que el empleo de metodos asistidos por ultrasonido resultan ser mas eficientes y economicos que los metodos convencionales reportados (autoclave), ademas tienen la ventaja, de poder controlar propiedades tales como: la cristalinidad, la porosidad y la superficie

Development of an analytic outline for the aflatoxins analysis in grains and flours; Desarrollo de un esquema analitico para el analisis de aflatoxinas en granos y harinas

Energy Technology Data Exchange (ETDEWEB)

Sibaja Adams, Roxana

2000-07-01

The instrumental and analytic conditions were optimized for the aflatoxine determination B1, B2, 1 and G2 in corn and peanut byl iquid chromatography of high discharge following the analyzing method AOAC 994,08. Besides, it was defined a function for evaluating the dependence of the chromatographic discharge with the aflatoxine concentration. The analyzing method was validated, and four calibration curves were obtained for the aflatoxine B1, B2, G1 and G2, which turned to have a heterocedastico behavior. The applicability of this method was demonstrated, obtaining imagines of appropriate merit and comparable with those reported by the AOAC. Additionally, the applicability of the chromatographic method was demonstrated in fine layer for the presumptive analysis of aflatoxine, allowing both methods to propose an outline of reliable analysis of real samples. [Spanish] Se optimizaron las condiciones instrumentales y analiticas para la determinacion de aflatoxinas B1, B2, G1 y G2 en maiz y mani por Cromatografia liquida de alto desempeno siguiendo el metodo de analisis AOAC 994,08. Ademas, se definio una funcion para evaluar la dependencia del desempeno cromatografico con la concentracion de aflatoxinas.Se valido el metodo de analisis y se obtuvieron las cuatro curvas de calibracion para las aflatoxinas B1, B2, G1 y G2, las que resultaron tener un comportamiento heterocedastico. Se demostro la aplicabilidad del metodo, obteniendose figuras de merito adecuadas y comparables con las reportadas por el AOAC.Adicionalmente, se demostro la aplicabilidad del metodo de cromatografia en capa fina para el analisis presuntivo de aflatoxinas, permitiendo ambos metodos proponer un esquema de analisis confiable de muestras reales.

Analytic computation of the quantum levels of a two-dimensional hydrogenic donor in the presence of a constant magnetic field of arbitrary strength

Energy Technology Data Exchange (ETDEWEB)

Villalba, Victor M.; Pino, Ramiro [Instituto Venezolano de Investigaciones Cientificas, Caracas (Venezuela)

2001-03-01

In this article we review different techniques for computing the energy spectrum of 2 D hydrogenic donors and two-electron quantum dots in the presence of a constant, magnetic field perpendicular to the plane of the electron. We compute the 1S, 2P- and 3D- energy levels via a scaled variational mixed-bases method. We compare our results with those obtained with the shifted 1/N method. [Spanish] En el presente articulo se exhiben distintos metodos para calcular el espectro de energia de donores hidrogenicos y puntos cuanticos con dos electrones en presencia de un campo magnetico constante perpendicular al plano del electron. Se calculan los niveles de energia 1S, 2P- y 3D- con ayuda del metodo variacional de bases mixtas con escalamiento. Comparamos nuestro resultados con los obtenidos con ayuda del metodo 1/N con corrimiento.

Expressão imunoistoquímica da endoglina (CD105 e do fator de von Willebrand em carcinoma epidermoide oral e sua relação com parâmetros clinicopatológicos

Directory of Open Access Journals (Sweden)

Rodrigo Porpino Mafra

2016-03-01

Full Text Available Resumo Contexto A angiogênese tem sido associada à progressão de neoplasias malignas e, embora haja estudos acerca de marcadores angiogênicos no carcinoma epidermoide oral (CEO, existem resultados conflitantes na literatura. Objetivos Avaliar a expressão imunoistoquímica do CD105 e do fator de von Willebrand (FvW em CEO e sua relação com parâmetros clínicos do tumor. Métodos A imunoexpressão dos referidos biomarcadores foi analisada em 30 casos de CEO e correlacionada a parâmetros clínicos do tumor (idade e sexo dos pacientes, localização anatômica e estadiamento clínico Tumor, Nodo e Metástase, TNM. Resultados A imunomarcação com o anticorpo anti-FvW foi mais efetiva que a do CD105 no CEO. No que concerne à localização anatômica, o assoalho bucal e a região retromolar apresentaram diferenças estatisticamente significativas quanto aos índices angiogênicos (p = 0,004, determinados pela técnica de contagem microvascular (MVC. Não houve relação estatisticamente significativa entre o estadiamento clínico TNM e os índices angiogênicos, com os dois biomarcadores. Conclusões Com base nos achados deste estudo, sugere-se um envolvimento da neoformação vascular na carcinogênese oral, embora não tenha sido evidenciada associação significativa com o estágio clínico da lesão.

O impacto do nível da metástase cervical no prognóstico dos pacientes com carcinoma epidermoide de cavidade oral Prognostic impact of the level of neck metastasis in oral cancer patients

Directory of Open Access Journals (Sweden)

Hugo Fontan Köhler

2012-12-01

Full Text Available Em pacientes com carcinoma epidermoide oral, classifica-se o pescoço pelo número, tamanho e lateralidade das metastáses. OBJETIVO: Avaliar fatores de risco para metástase em nível IV/V e seu impacto no prognóstico do carcinoma epidermoide oral. MÉTODO: Estudo retrospectivo. Critérios de inclusão foram: diagnóstico de CEC, sítio primário em andar inferior da boca sem extensão para sítios extraorais, ausência de tratamento prévio, realização de EC e presença de metástases linfáticas. Por regressão logística, definiram-se fatores de risco e por análise de sobrevivência, fatores prognósticos de recorrência. Análise classificatória realizada por particionamento recursivo. RESULTADOS: Foram incluídos 307 pacientes. Em regressão logística univariada, o estágio pN, embolização vascular, e múltiplos linfonodos comprometidos foram fatores de risco para metástases em nível IV/V. Embolização vascular e múltiplos linfonodos comprometidos permaneceram significativos em análise multivariada. A análise de sobrevivência demonstrou os estágios pT e pN, infiltração perineural, embolização vascular, número de linfonodos metastáticos, razão linfonodal e metástases em níveis IV/V como significativos. Na análise multivariada, PT, pN, embolização vascular linfática e metástases em níveis IV/V permaneceram significativas. Na análise classificatória, o estágio pN não foi significativo quando há metástases em níveis IV/V. CONCLUSÃO: A ocorrência de metástases em níveis IV/V foi significativa para sobrevivência doença-específica.Neck staging in oral cancer depends on the number of compromised nodes, their size and side of occurrence. OBJECTIVE: This paper aims to evaluate risk factors for metastatic nodes in levels IV/V and their prognostic impact on patients with oral carcinoma. METHOD: Retrospective study. Inclusion criteria: pathologist's diagnosis of squamous cell carcinoma, primary tumor in the

Sviluppo e validazione di un antigene-capture ELISA basato su anticorpi monoclonali specifici per Listeria monocytogenes negli alimenti

Directory of Open Access Journals (Sweden)

Rossella Lelli

2011-09-01

Full Text Available È stato standardizzato e validato un dosaggio immunoenzimatico capture ELISA per l’identificazione di Listeria monocytogenes negli alimenti. Il dosaggio è stato messo a punto analizzando campioni di prodotti carnei, ittici e lattiero-caseari, pasta di semola e di farina di grano. Il metodo è risultato specifico al 100% per Listeria spp., con limite di rivelazione di 6,6 × 10(3 cfu/ml. Il metodo L. monocytogenes capture ELISA è stato confrontato con il metodo ufficiale ISO 11290-1:1996 per l’isolamento e l’identificazione di L. monocytogenes in matrici alimentari ottenendo un indice di concordanza significativo. Il dosaggio è stato validato in base alle indicazioni della norma ISO 16140:2003 relativamente ai metodi di analisi qualitativi. Il dosaggio è risultato accurato, specifico, sensibile, selettivo, riproducibile e rapido da eseguire, consentendo nello screening degli alimenti la riduzione di tempi e costi dell’indagine microbiologica.

Rapid Methods of Determining Internal Radioactive Contamination; Methodes Rapides Permettant d'Evaluer la Contamination Radioactive Interne; 0411 042b 0414 ; Metodos Rapidos para Determinar la Contaminacion Radiactiva Interna

Energy Technology Data Exchange (ETDEWEB)

Sedlet, J.; Fairman, W. D.; Robinson, J. J. [Industrial Hygiene and Safety Division, Argonne National Laboratory, Argonne, IL (United States)

1965-06-15

, il est possible de l'atteindre. Les emetteurs alpha et les emetteurs beta purs de faible energie presentent la plus grande difficulte du fait que les charges corporelles de ces nucleides doivent ordinairement etre evaluees par une analyse radiochimique du sang ou des excreta. Les auteurs decrivent les separations radiochimiques qui ont ete mises au point et appliquees au Laboratoire national d*Argonne pour doser rapidement ces emetteurs. Le memoire examine d'autre part certains problemes que pose l'obtention de charges corporelles a partir des taux d'excretion, peu apres l'absorption. Pendant ce laps de temps, l'excretion se modifie rapidement et, pour beaucoup de nucleides importants en l'occurrence, a un taux inconnu. Pour les taux d'absorption tres eleves ou tres bas, il n'est pas necessaire de connaitre immediatement la mesure precise des charges corporelles. Cependant, il existe pour chaque radionucleide une dose d'absorption intermediaire pour laquelle il faut pouvoir -determiner sans trop tarder la charge corporelle avec une precision relative, ce qui permet de decider ou non le traitement. Les auteurs examinent les proprietes et les facteurs qui rendent le dosage des elements osteotropes particulierement difficile dans les cas d'accident. (author) [Spanish] Los metodos aplicables en casos de accidente o en situaciones excepcionales tienen que ser suficientemente rapidos y sensibles para proporcionar resultados en plazos que faciliten el tratamiento eficaz de las personas sobreexpuestas. Los plazos disponibles dependeran, en parte, del numero de individuos irradiados. Si se logra obtener en pocas horas resultados utiles, se habra cumplido la funcion primaria de las mediciones rapidas de la carga corporal, que es la de contribuir en toda la medida de lo posible a reducir los danos debidos .a radionuclidos depositados internamente. Los metodos que se citan a continuacion pueden servir para evaluar la contaminacion interna en casos de accidente: recuento gamma y

Reconocimiento automa?tico a trave?s de visio?n artificial, correlacio?n estadi?stica y Matlab aplicado a las matri?culas de vehi?culos

OpenAIRE

Barcia, Orlando

2014-01-01

Existen muchas investigaciones sobre el reconocimiento de caracteres e ima?genes utilizando diferentes me?todos tales como redes neuronales, me?todos estructurales, basados en la apariencia y otros (Pajares Martinsanz & De La Cruz Garci?a, 2008a). El problema es el reconocimiento automa?tico de caracteres en las placas o matri?culas de los vehi?culos del Ecuador. El trabajo innova en la aplicacio?n de las te?cnicas de visio?n artificial, adaptando el reconocimiento de las matri?culas de los v...

Radiaciones electromagnéticas

OpenAIRE

Borrero, Luis M.

2010-01-01

I-La luz; II-El infrarrojo; III-El ultravioleta; IV-Los rayos X. Los rayos gamma. Los rayos intermediarios o de Holweck. Las ondas cortas y las corrientes de alta frecuencia. ResumenIlustraciones: Los rayos cósmicos

Caracterización clinicopatológica de los tumores malignos palpebrales

Directory of Open Access Journals (Sweden)

Lázara Kenia Ramírez García

Full Text Available Objetivos: describir las características clinicopatológicas de los tumores malignos palpebrales. Métodos: estudio descriptivo y retrospectivo de pacientes con diagnóstico histopatológico de carcinoma basocelular, epidermoide y adenocarcinoma de glándulas sebáceas, atendidos en el Servicio de Oculoplastia del Instituto Cubano de Oftalmología, de enero de 2005 a diciembre de 2010. Se incluyó un total de 109 pacientes; se analizó la edad, el sexo, el color de la piel, las formas clínicas, la localización anatómica, el grado de diferenciación celular y la frecuencia anual. Resultados: el grupo de edad entre 60 y 79 años constituyó el 50,5 % de los casos. El sexo masculino constituyó el 47,7 % y el femenino el 52,3 %. El carcinoma basocelular se presentó en el 68,8 % de los pacientes, el carcinoma epidermoide en el 19,3 % y el adenocarcinoma de glándulas sebáceas en el 11,9 %. La piel blanca mostró el 88 % de los casos; el carcinoma basocelular nodular estuvo presente en el 53,3 % y la noduloulcerativa en 33,3 %. En el párpado inferior se presentó el carcinoma basocelular en el 69,3 % y el epidermoide en el 66,7 %. El 44,1 % de los diagnósticos histopatológicos fueron moderadamente diferenciados. Mostró 21 casos de carcinoma basocelular en el 2009; 7 de carcinoma epidermoide en el 2007 e igual número de casos de adenocarcinoma de glándulas sebáceas en el 2010. Conclusiones: más de la mitad de los pacientes que presentan tumores malignos palpebrales son adultos mayores, femeninos y blancos. Se evidencia la totalidad de las formas clínicas de presentación; predomina en el párpado inferior el carcinoma basocelular y el epidermoide. La mayoría de los casos muestra grado de diferenciación celular moderado y la frecuencia anual tiene disímil comportamiento.

Results of surgical treatment versus chemoradiation therapy in oropharyngeal early tumors

Directory of Open Access Journals (Sweden)

Chedid, Helma Maria

2009-03-01

Full Text Available Introduction: The epidermoid carcinoma of the upper aerodigestive tract is diagnosed in approximately 40% of the cases of advanced clinical stages. Objective: To evaluate the disease-free interval in patients with clinical stages I and II epidermoid carcinoma who were submitted to surgery or chemoradiation. Method: Retrospective study of the records of 139 patients treated for oropharyngeal epidermoid carcinoma submitted to treatment with curative intent. Among those patients, 38 were classified with early tumors clinical stages I and II. Twenty-seven (71.1% underwent surgical treatment whereas eleven (28.9% were treated with chemoradiation. The mean age was 56.4 years; 31 cases (81.6% were in men and seven (18.4% were in women. Results: Among the eleven patients who were submitted to chemoradiation, 72.7% obtained locoregional control of the disease and their disease-free survival was of 42%. Among the 27 patients operated, 19 remained in Clinical Stages I and II in the histological report and six underwent postoperative radiation therapy. The disease-free interval for two years was of 70%. Conclusion: The patients submitted to the surgery had a better disease-free interval as compared to those submitted to chemoradiation treatment.

Isolation and characterization of gallic acid and methyl gallate from the seed coats of Givotia rottleriformis Griff. and their anti-proliferative effect on human epidermoid carcinoma A431 cells

Directory of Open Access Journals (Sweden)

Samuel Kamatham

2015-01-01

Full Text Available Gallic acid (GA and its derivative methyl gallate (MG are well studied plant phenolics. They have exhibited anticancer effects in several cancer cell lines. However, the presence of GA/MG in the seed coats of Givotia rottleriformis and their inhibitory effect on human epidermoid carcinoma (A431 skin cancer cells were not reported. In this study we have isolated and chemically characterized the bioactive compounds GA and MG from the bioassay guided methanolic (MeOH seed coat extracts of G. rottleriformis. The fractions obtained from open silica column chromatography were subjected to in vitro enzymatic assays. Among seven fractions we found that only fractions 5 and 6 showed significant inhibition activity toward COX-1 with an IC50 value of 28 μg/mL and 9.3 μg/mL and COX-2 with an IC50 value of 35 μg/mL and 7.0 μg/mL respectively. However, we could not find 5-LOX enzyme inhibition activity. MG (10 mg/g DW and GA (6 mg/g DW were the major compounds of seed coats. Cell viability was analyzed by 3-(4,5-dimethylthiazol-2-yl-2,5-diphenyl tetrazolium bromide (MTT assay, which showed that GA/MG significantly reduced the growth of A431 cells with an IC50 value of 25 μg/mL and 53 μg/mL and 11 μg/mL and 43 μg/mL at 24 h and 48 h, respectively. However the cytotoxic effect of GA/MG on HaCaT normal skin keratinocyte cell line was found to be less. Western blot analysis has shown that GA/MG treatment down regulated Bcl-2 and up regulated cleaved caspase-3 with respect to increasing doses. Our results conclude that GA and MG have potential anticancer effects and can be used as therapeutic agents for skin cancers.

A GENERAL ANALYTICAL APPROACH FOR PRESTRESSED AND NON-PRESTRESSED CONCRETE BEAM-COLUMNS REINFORCED WITH BONDED AND UNBONDED COMPOSITES: (I THEORY

Directory of Open Access Journals (Sweden)

J. A. RODRIGUEZ-GUTIÉRREZ

2011-01-01

Full Text Available Se propone un metodo de analisis que determina la respuesta a corto y largo plazo de vigas columnas de hormigon pretensado y no pretensado reforzado con cualquier combinacion de barras de FRP y/o placas, barras de acero, torones pretensados adheridos o no adheridos. El metodo de analisis propuesto incluye vigas y columnas revestidas con telas FRP y tubos de FRP rellenos de hormigon. Tambien se incluyen los efectos de la rigidez a traccion, fluencia y retraccion del hormigon y la relajacion de la armadura de acero pretensado. Se adoptan los modelos de Vecchio y Collins [1] y de Popovics [2, 3] en las relaciones esfuerzo-deformacion del hormigon a traccion y a compresion, respectivamente. Las relaciones esfuerzo-deformacion de los refuerzos de acero y de FRP se modelan mediante lineas rectas multiples (esto es, lineas poligonales. El metodo de las fibras (modificado es utilizado para calcular los diagramas momento-curvatura a diferentes niveles de la carga axial aplicada (es decir, las curvas M-P-¿Ö y el metodo de Gauss de integracion (para la suma de las contribuciones de los fibras paralelas al eje neutro para calcular las rotaciones laterales y deflexiones a lo largo de la luz de la viga-columna. La validez del modelo propuesto y las ecuaciones correspondientes se pusieron a prueba con datos experimentales disponibles en la literatura tecnica (vease la parte II de esta publicacion.

Double-Sampling Method for Carrying Out Quality Control of a Fabrication Process; Methode du Double Echantillonnage pour le Controle de la Qualite d'un Procede de Fabrication; Metod dvukh obraztsov dlya osushchestvleniya kontrolya za kachestvom v protsesse izgotovleniya; Metodo de Muestreo Doble para el Control de Calidad de un Proceso de Fabricacion

Energy Technology Data Exchange (ETDEWEB)

Cerrolaza, J. A.; Lago, A.; Montojo, Rosa M. [Junta de Energia Nuclear, Madrid (Spain)

1966-02-15

taille des echantillons et le degre de controle sont determines en fonction des risques inherents a la premiere et a la deuxieme condition. Bien que cette methode soit applicable, elle est fort peu pratique quand il s'agit de controler des pieces de reacteurs, car les echantillons qu'elle exige sont de dimensions excessives. Le memoire expose une methode analogue a celle de Cave mais qui consiste a etablir un double echantillonnage dans lequel la taille moyenne de l'echantillon est beaucoup plus reduite. (author) [Spanish] La fabricacion de componentes que han de ser empleados en reactores nucleares presenta dos caracteristicas fundamentales que condicionan el proceso: la exigencia de una calidad muy elevada que limita a valores muy bajos el porcentaje de piezas defectuosas admisibles, y el coste muy alto de cada uno de los componentes. Estas dos condiciones obligan a que el control durante la fabricacion posea una curva de operacion con potencia muy elevada, y, por otra parte, a que el numero de piezas destruidas en cada inspeccion sea un pequeno como se pueda, siempre que se cumpla la condicion anterior. Los metodos usuales de control, basados en fijar el riesgo de primera especie, no son aplicables, ya que en general su eficacia no es suficiente. Cave ha desarrollado un metodo en que, tanto el tamano de las muestras como los limites de control, se fijan en funcion de los riesgos de primera y segunda especie. Este metodo, si bien es aplicable, resulta poco practico en el control de componentes para reactores, ya que se necesitan muestras de un tamano excesivamente grande. En el presente trabajo se desarrolla un metodo semejante al de Cave, pero en el que se establece un muestreo doble, con lo que el tamano medio de la muestra es mucho mas reducido. (author) [Russian] Pri izgotovlenii komponentov dlja ispol'zovanija v reaktorah reshajushhee znachenie imejut dva osnovnyh faktora, a imenno: neobhodimost' obespechit' ochen' vysokoe kachestvo, dopuskajushhee lish' ochen

Multispectral fluorescence imaging for detection of bovine feces on Romaine lettuce and baby spinach leaves

Science.gov (United States)

Hyperspectral fluorescence imaging with ultraviolet-A excitation was used to evaluate the feasibility of two-waveband fluorescence algorithms for the detection of bovine fecal contaminants on the abaxial and adaxial surfaces of Romaine lettuce and baby spinach leaves. Correlation analysis was used t...

Long-term results and prognostic factors of squamous cell carcinoma of the anal canal treated by irradiation; Resultats a long terme et facteurs pronostiques des carcinomes epidermoides du canal anal traites par irradiation

Energy Technology Data Exchange (ETDEWEB)

Tournier-Rangeard, L.; Peiffert, D.; Lafond, C.; Mege, A. [Centre Alexis-Vautrin, Dept. de Radiotherapie et Curietherapie, 54 - Vandoeuvre-les-Nancy (France); Metayer, Y.; Marchesi, V.; Buchheit, I. [Centre Alexis-Vautrin, Dept. de Radiophysique, 54 - Vandoeuvre-les-Nancy (France); Uwer, L.; Conroy, T.; Kaminsky, M.C. [Centre Alexis-Vautrin, Dept. d' Oncologie Medicale, 54 - Vandoeuvre-les-Nancy (France)

2007-06-15

Purpose To analyze the prognostic factors of loco regional control (L.R.C.), specific survival (S.S.) and sphincter conservation (S.C.) of patients treated by curative and conservative irradiation for an epidermoid cancer of anal canal in our institution. Patients and methods From 1976 to 2005, 286 patients (pts) were treated by exclusive radiotherapy (180 pts) or chemo-radiotherapy (106 pts) followed by a brachytherapy boost (233 pts) or external beam radiotherapy boost (24 pts). Forty-three pts were stage I, 154 stage II, 31 stage IIIA and 53 stage IIIB. Results The mean follow-up was 65 months (range: 1.3-250 months). The 5-years-overall survival and S.S. rates were 66.4% and 78.1% respectively. In multivariate analysis, tumor size (? 40 mm) [R.R. = 2.1], node involvement (R.R. = 2.4), and poor response (< 75%) to first course irradiation [R.R. = 1.9], local relapse (R.R. = 4.5) and distant metastases were factors of poor prognosis for S.S.. Five-years-L.R.C. were 71.5% (88% for stage I, 69% for stage II, 77%, for stage IIIA and 60% for stage IIIB). Prognosis factors of L.C.R. were tumor size (R.R. = 2.5), response to first course of irradiation (R.R. = 2.9). S.C. was 71% at 5 years. Prognosis factors of S.C. were tumor size (R.R. = 1.9) and response to first course of irradiation (R.R. = 2.4). Conclusion The results of this series are similar to those of the literature. As well as initial tumor extension, response to first course of irradiation was found as prognostic factor on L..R., S.S., S.C.. Our results are similar to other series and brachytherapy seems not to be deleterious. Its impact to local control remains to be evaluated. (authors)

Índice UV

Science.gov (United States)

Información general sobre el Índice UV que proporciona un pronóstico del riesgo esperado de sobreexposición a la radiación ultravioleta (UV) del sol. El índice UV va acompañado de recomendaciones para protegerse del sol.

Lymphatic mapping inguinal and sentinel lymph node biopsy in anal canal cancers to avoid prophylactic inguinal irradiation; Le marquage lymphatique et la biopsie du ganglion sentinelle inguinal dans les cancers du canal anal pour eviter l'irradiation inguinale prophylactique

Energy Technology Data Exchange (ETDEWEB)

Bobin, J.Y. [Centre Hospitalier Universitaire Lyon-Sud, Service de Chirurgie Oncoloque, 69 - Pierre-Benite (France); Gerard, J.P.; Chapet, O.; Romestaing, P. [Centre Hospitalier Universitaire Lyon-Sud, Dept. de Radiotherapie et Oncologie, 69 - Pierre-Benite (France); Isaac, S. [Centre Hospitalier Universitaire Lyon-Sud, Dept. d' Anatomopathologie, 69 - Pierre-Benite (France)

2003-11-01

Thirty-five patients with clinically N0 cancers of the canal anal, 33 epidermoid carcinomas et 2 melanomas were histologically staged with inguinal sentinel lymphode biopsy (ISN). With the combined technique, blue dye and radiocolloid the ISN was identified in 100 % of the cases. The ISN was invaded in 7 cases/33 for epidermoid tumors and 2/2 for melanomas. After 18 months of follow-up, no inguinal recurrence could be seen in ISN pN0 cases. In conclusion, ISN biopsy is a reliable procedure to stage anal,, canal cancers. It should prevent unnecessary prophylactic inguinal irradiation for pN0 ISN. Inguinal irradiation is only indicated in pN1 ISN. (author)

Soluciones analiticas AL problema de jets con velocidad de eyeccion variable EN EL tiempo.

Science.gov (United States)

Canto, J.; Raga, A. C.; D'Alessio, P.

1998-11-01

Se presenta un nuevo metodo que permite resolver de manera exacta y analitica las ecuaciones que describen un jet hipersonico con velocidad de eyeccion variable en el tiempo. El metodo se basa en consideraciones sencillas de conservacion de momento para las superficies de trabajo que se forman en el interior del jet. Como ejemplo, se presentan soluciones para jets con variacion sinusoidal en la velocidad de eyeccion, y tambien para el caso de un incremento lineal en el tiempo. Estas soluciones analiticas tienen una clara aplicacion en la interpretacion de las observaciones de jets asociados a objetos Herbig-Haro.

Efectos de la radiación UV en la salud

Science.gov (United States)

La reducción de la capa de ozono disminuye la protección natural que ofrece nuestra atmósfera contra la radiación ultravioleta (UV) perjudicial del sol. Esta página web proporciona una descripción general de los principales problemas de salud relacionados

Antimicrobial susceptibility of photodynamic therapy (UVA/riboflavin against Staphylococcus aureus Suscetibilidade antimicrobiana da terapia fotodinâmica (UVA/riboflavina contra Staphylococcus aureus

Directory of Open Access Journals (Sweden)

Renata Tiemi Kashiwabuchi

2012-12-01

Full Text Available PURPOSE: To assess S. aureus in vitro viability after the exposure to ultraviolet light A (UVA and riboflavin (B2. METHODS: Samples of S. aureus in 96 well plates (in triplicate were exposed to riboflavin (B2 and ultraviolet light A (365 nm wavelength at a power density of 3 mW/cm², 8 mm spot diameter, for 30 minutes. Control groups were prepared as well in triplicate: blank control, ultraviolet light A only, riboflavin only and dead bacteria Control. The bacterial viability was measured using fluorescent microscopy. In order to investigate the occurrence of "viable but non-culturable" microorganisms after treatment, the cell viability was also investigated by plate culture procedure onto a broth medium. Statistical analysis was performed using the triplicate values from each experimental condition. RESULTS: No difference was observed among the treatment group and the control samples (p=1. CONCLUSION: The combination of riboflavin 0.1% and ultraviolet light A at 365 nm did not exhibit antimicrobial activity against oxacillin susceptible S. aureus.OBJETIVO: Avaliar a viabilidade celular de S. aureus in vitro após a exposição de riboflavina (B2 e luz ultravioleta A (UVA. MÉTODOS: Amostras de S. aureus colocadas em uma placa de 96 poços (em triplicata foram expostas a riboflavina 0,1% (B2 e luz ultravioleta (comprimento de onda de 365 nm poder de 3 mW/cm², 8 mm de diâmetro, por 30 minutos. Grupos controles foram também preparados em triplicata: controle branco, somente luz ultravioleta A, somente riboflavina e controle morto. A viabilidade bacteriana foi analisada usando microscópio de fluorescência. Para investigar a ocorrência de micro-organismos "viáveis porem não cultiváveis" a viabilidade celular foi avaliada utilizando-se placas de meio de cultivo bacteriano. Analise estatística foi realizada utilizando-se os valores obtidos em triplicata de cada grupo experimental. RESULTADOS: Nenhuma diferença foi observada entre o grupo

Retrorectal Cystic Hamartoma: A Problematic 'Tail'

African Journals Online (AJOL)

and developmental cysts (dermoid, epidermoid, enteric ... menstrual cycle. General physical and per abdominal examination revealed no abnormal findings. .... bleeding.[1,2] CT and magnetic resonance imaging (MRI) are useful imaging ...

Carcinoma epidermoide (variante pequenas células vs. carcinoma de pequenas células do pulmão: diagnóstico diferencial em material de biópsia Small cell variant of squamous cell carcinoma vs. small cell carcinoma of the lung: differential diagnosis in biopsies

Directory of Open Access Journals (Sweden)

Rachel Martins Marinho

2010-04-01

Full Text Available O diagnóstico diferencial entre a variante pequenas células do carcinoma epidermoide e do carcinoma de pequenas células nem sempre é fácil. Apesar de os descritores alertarem que o primeiro deva manter suas características morfológicas e, muitas vezes, diferenciação escamosa focal, a escassez de material aliada a artefatos de fixação frequentes nessas biópsias podem dificultar a vida do patologista. Entretanto, a definição entre um e outro pode alterar significativamente a escolha da modalidade terapêutica do paciente e, em alguns casos, influenciar seu prognóstico. Procuramos nesta publicação alertar para o problema e facilitar essa diferenciação, sugerindo um painel imuno-histoquímico.The differential diagnosis between small cell variant of squamous carcinoma and small cell carcinoma is not always simple. Despite the fact that studies show the former keeps its morphologic characteristics and focal squamous differentiation, the scarcity of the material as well as frequent fixation artifacts in these biopsies may hinder analysis. However, this differentiation between them may change significantly the choice of therapeutic approach and, in some cases, influence prognosis. In this paper, we draw attention to this problem and suggest a immunohistochemical panel to facilitate this differential diagnosis.

Analytic techniques to quantify Tetrachlorohydroquinone and Chloranil; Tecnicas analiticas para cuantificar Tetraclorohidroquinona y Cloranilo

Energy Technology Data Exchange (ETDEWEB)

Castillo Escobedo, Ma. Teresa; Gutierrez de Gonzalez, Luz Ma; Gojon Zorrilla, Gabriel [Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon (Mexico)

1995-02-01

Tetrachlorohydroquinone (TCHQ) was determined by two methods: iodometry and cerimetry. Tritation with aqueous ceric ammonium sulphate using potentiometric end-point detection proved to be the method of choice on account of its coefficient of variation (CV=0.475%) and its excellent accuracy. Chloranil (TCQ) was quantified by titration with aqueous ascorbic acid in acetone-water-hexamethylene tetramine (HMT), the golden-yellow color of the TCQ-HMT complex disappearing at the end point. This method is accurate and has CV=0.396%. [Spanish] Se cuantifico la tetraclorohidroquinona (TCHQ) mediante una tecnica yodometrica y un metodo potenciometrico, basado en el uso de sulfato cerico amoniacal. Se concluyo que el metodo potenciometrico es el mejor, ya que tiene un coeficiente de variacion (CV) de 0.475%, y una exactitud muy aceptable. Se desarrollo un tecnica para cuantificar el Cloranilo (TCQ) por titulacion con Acido Ascorbico en presencia de Hexametilentetramina (HMT) en medio acetona-agua; el punto final se determino por la separacion del color amarillo oro del complejo TCQ-HMT. Esta tecnica presenta un coeficiente de variacion (CV) de 0.396% y una exactitud aceptable. Se realizaron pruebas de hipotesis para verificar la exactitud de los metodos elegidos.

ELENA MODENA, L'altrOrfeo. Considerazioni analitiche sulla vocalità, Roma, Aracne, 2009

Directory of Open Access Journals (Sweden)

Adriana Guarnieri

2012-11-01

Full Text Available Il volume propone un’indagine sulla vocalità ispirata al «metodo funzionale della voce» di Gisela Rohmert, didatta e fondatrice del Lichtenberger Institut für angewandte Stimmphysiologie, attivo in Germania dal 1982 . Da quell'esperienza – un metodo di pedagogia della voce fondato sullo studio della fisiologia vocale e del «fatto vocale» in quanto evento acustico e stimolo percettivo – Elena Modena ha derivato e illustra in questo libro una sua proposta di «analisi funzionale» della vocalità, storicamente considerata e rivolta, insieme, all’àmbito dell’emissione e a quello dell’ascolto.

Cytoplasmic expression of survivin is an independent predictor of poor prognosis in patients with salivary gland cancer.

Science.gov (United States)

Stenner, Markus; Weinell, Antje; Ponert, Tobias; Hardt, Aline; Hahn, Moritz; Preuss, Simon F; Guntinas-Lichius, Orlando; Klussmann, Jens Peter

2010-11-01

The expression of the inhibitor of apoptosis protein survivin has been shown to be a significant prognostic indicator in various human cancers. The aim was to assess its expression and prognostic value in salivary gland adenocarcinoma and muco-epidermoid carcinoma. Survivin expression was analysed in 48 patients with parotid gland cancer (21 muco-epidermoid, 27 adenocarcinomas) by means of immunohistochemistry. The experimental findings were correlated with clinicopathological and survival parameters. A high cytoplasmic expression of survivin was found in 30% of the examined tumours without any significant correlation with the patients' clinicopathological characteristics (P > 0.05). Within all patients, the estimated overall survival rate of muco-epidermoid carcinomas was significantly better than that of adenocarcinomas (P = 0.013). A high cytoplasmic survivin expression significantly indicated a poor 5-year disease-free survival rate compared to patients with a low cytoplasmic survivin expression in the whole group (P = 0.001) and in adenocarcinomas (P = 0.004). In a multivariate analysis, a high cytoplasmic survivin expression was the only independent prognostic indicator for a significantly poorer 5-year disease-free survival rate (P = 0.001). The correlation between cytoplasmic survivin expression and survival in salivary gland malignancies might make this an effective tool in patient follow-up, prognosis and targeted therapy in future. © 2010 Blackwell Publishing Limited.

New Cytotoxic Triterpenoid Saponins from the Roots of Albizia gummifera (J.F.Gmel.) C.A.Sm.

Science.gov (United States)

Simo, Line Made; Noté, Olivier Placide; Mbing, Joséphine Ngo; Aouazou, Sarah Ali; Guillaume, Dominique; Muller, Christian Dominique; Pegnyemb, Dieudonné Emmanuel; Lobstein, Annelise

2017-10-01

As part of our search for new bioactive saponins from Cameroonian medicinal plants, two new oleanane-type saponins, named gummiferaosides D and E (1 and 2), along with one known saponin, julibroside J 8 (3), were isolated from the roots of Albizia gummifera. Their structures were established on the basis of extensive 1D- and 2D-NMR ( 1 H- and 13 C-NMR, DEPT, COSY, TOCSY, NOESY, HSQC, HSQC-TOCSY, and HMBC) and HR-ESI-MS studies, and by chemical evidence. The apoptotic effect of saponins 1 - 3 was evaluated on the A431 human epidermoid cancer cell. Flow cytometric analyses showed that saponins 1 - 3 induced apoptosis of human epidermoid cancer cell (A431) in a dose-dependent manner. © 2017 Wiley-VHCA AG, Zurich, Switzerland.

Statistical report on lung cancer irradiated in three hospital in Gunma Prefecture

International Nuclear Information System (INIS)

Yamanaka, Mikio; Saito, Yoshihiro; Ikeda, Hajime

1982-01-01

The data on 158 cases of lung cancer treated with radiotherapy at three hospitals (Hospital of School of Med., Gunma Univ., National Takasaki Hospital and Gunma Cancer Center Hospital) were analized. 1. Seventy one cases (44.9%) of all patients were more than 70 years old. As the histological type, epidermoid carcinoma was recognized in 44% of male patients, and adenocarcinoma in 51.5% of female. The number of patients with epidermoid carcinoma tended to increase with age. 2. Gunma Cancer Center was different from other hospitals in that half of the female patients (6/12) were stage I, adenocarcinoma. 3. The dwelling area of patients in Gunma Cancer Center Hospital distributed over towns and counties at the east district in Gunma prefecture, whereas in other hospitals concentrated in Maebashi and Takasaki cities. (author)

Adenocancróide primário do estômago Primary adenocancroid of the stomach

Directory of Open Access Journals (Sweden)

Eitel Duarte

1949-06-01

Full Text Available Os AA. referem um caso de blastoma primitivo do estômago, mostrando a par das estruturas de adenoma destruens e de adenocarcinoma, a de carcinoma epidermoide. O tumor corresponde ao tipo descrito no literatura como adenocancroide e apresenta metástases no figado, gânglios linfáticos regionais, apêndice cecal, colon transverso, peritônio e diafragma. Uma revisão da literatura e discussão sobre a origem de tais tumores são apresentadas.The AA. report a case of adenocancroid of the stomach (aged colored male, with metastasis in the liver, regional lymph nodes, vermiform appendix, transverse colon, peritoneum and diaphragm. The structure was not uniform, and was referred as adenoma destruens, adenocarcinoma and epidermoid carcinoma, according to the field under examination.

Recomendaciones para la fotoprotección en la edad pediátrica, una propuesta basada en evidencias científicas

Directory of Open Access Journals (Sweden)

Pilar María Acuña Aguilarte

Full Text Available Introducción: el incremento mundial del cáncer de piel y otras afecciones relacionadas con las radiaciones ultravioletas ha sido reconocido por la Organización Mundial de la Salud, que ha llamado a trazar estrategias de prevención. En el mundo existen diferentes posturas relacionadas con la fotoprotección, y la Organización Mundial de la Salud, entre sus recomendaciones, enfatiza en no exponer a las radiaciones ultravioletas de forma directa a los niños menores de 1 año, pero las recomendaciones varían entre países y organismos internacionales. Objetivo: elaborar recomendaciones basadas en evidencias científicas para la fotoprotección de niños y adolescentes cubanos. Desarrollo: se empleó un diseño cualitativo, con un acercamiento de investigación documental. Se emplearon motores de búsqueda y bases de datos disponibles en la Biblioteca Virtual de Salud, y se buscaron descriptores relacionados con el tema de fotoprotección, publicados en inglés y español entre 2002 y el 2012. Se obtuvieron evidencias científicas sobre el incremento de las radiaciones ultravioletas y su influencia en el ser humano. Se realizaron recomendaciones que fueron evaluadas por un grupo de expertos en el tema. Conclusiones: los puericultores pueden disponer de recomendaciones actualizadas para la fotoprotección de niños y adolescentes sanos cubanos, entre las cuales se incluyen, evitar la exposición directa del recién nacido a las radiaciones solares hasta los 6 meses de vida, clasificar el fototipo cutáneo de cada niño o adolescente y ofrecer indicaciones diferenciadas, así como dirigir la educación en las medidas de fotoprotección a toda la familia y la comunidad.

Corneal thickness changes during corneal collagen cross-linking with UV-A irradiation and hypo-osmolar riboflavin in thin corneas

Directory of Open Access Journals (Sweden)

Belquiz Amaral Nassaralla

2013-06-01

Full Text Available PURPOSE: To evaluate the thinnest corneal thickness changes during and after corneal collagen cross-linking treatment with ultraviolet-A irradiation, using hypo-osmolar riboflavin solution in thin corneas. METHODS: Eighteen eyes of 18 patients were included in this study. After epithelium removal, iso-osmolar 0.1% riboflavin solution was instilled to the cornea every 3 minutes for 30 minutes. Hypo-osmolar 0.1% riboflavin solution was then applied every 20 seconds for 5 minutes or until the thinnest corneal thickness reached 400 µm. Ultraviolet-A irradiation was performed for 30 minutes. During irradiation, iso-osmolar 0.1% riboflavin drops were applied every 5 minutes. Ultrasound pachymetry was performed at approximately the thinnest point of the cornea preoperatively, after epithelial removal, after iso-osmolar riboflavin instillation, after hypo-osmolar riboflavin instillation, after ultraviolet-A irradiation, and at 1, 6 and 12 months after treatment. RESULTS: Mean preoperative thinnest corneal thickness was 380 ± 11 µm. After epithelial removal it decreased to 341 ± 11 µm, and after 30 minutes of iso-osmolar 0.1% riboflavin drops, to 330 ± 7.6 µm. After hypo-osmolar 0.1% riboflavin drops, mean thinnest corneal thickness increased to 418 ± 11 µm. After UVA irradiation, it was 384 ± 10 µm. At 1, 6 and 12 months after treatment, it was 372 ± 10 µm, 381 ± 12.7, and 379 ± 15 µm, respectively. No intraoperative, early postoperative, or late postoperative complications were noted. CONCLUSIONS: Hypo-osmolar 0.1% riboflavin solution seems to be effective for swelling thin corneas. The swelling effect is transient and short acting. Corneal thickness should be monitored throughout the procedure. Larger sample sizes and longer follow-up are required in order to make meaningful conclusions regarding safety.

Valutazione dell'appropriatezza dei ricoveri in un Policlinico Universitario: analisi mediante l'uso comparativo dei sistemi di classificazione isogravitá APR-DRG e Disease Staging e del PRUO

Directory of Open Access Journals (Sweden)

M. Volpe

2003-05-01

Full Text Available

Obiettivi: valutare l’appropriatezza organizzativa dei ricoveri effettuati in un Policlinico Universitario attraverso la comparazione di due metodi, dei quali uno basato sui dati della scheda di dimissione ospedaliera ed utilizza, rispettivamente, i sistemi di classificazione iso-gravità APR-DRG e Disease Staging e l’altro sulla revisione delle cartelle cliniche mediante il PRUO.

Metodi: oggetto di analisi sono i ricoveri ordinari effettuati nell’anno 2001 ed afferenti ai DRG inclusi nella delibera della Giunta Regionale del Lazio 864/2002 che recepisce il D.P.C.M. 29/11/2001 sui livelli essenziali di assistenza.

Risultati: i risultati evidenziano che le due varianti del
metodo basato sulla SDO (metodo APPRO mostrano quote di ricoveri inappropriati sovrapponibili rispetto al complesso dei ricoveri oggetto di analisi, ma con differenze anche rilevanti tra APR-DRG e Disease Staging in relazione ai singoli DRG considerati, riconducibili ai diversi algoritmi di attribuzione del livello di severità utilizzati dai due sistemi. L’analisi campionaria effettuata con il metodo PRUO su casi afferenti ai DRG della DGR 864/2002 caratterizzati da livelli di severità minimi evidenzia una proporzione di ricoveri inappropriati superiore a quella determinata tramite i metodi basati sulla SDO. Tale differenza è verosimilmente dovuta al ruolo del valore delle soglie percentuali di accettabilità individuate dalla Regione Lazio per ciascun DRG: le quote di ricoveri che eccedono tali soglie sono considerate inappropriate.

Conclusioni: sulla base dei risultati ottenuti gli autori
descrivono gli interventi organizzativi adottati per ottimizzare il contesto di erogazione delle prestazioni
oggetto di analisi, discutono vantaggi e limiti dei metodi SDO-based e del metodo analitico PRUObased e ne propongono l�

Comparação entre dois métodos de detecção de DNA de papilomavírus humano em carcinoma epidermoide de lábio Comparison between two methods for human papilomavírus DNA detection in lip squamous cell carcinoma

Directory of Open Access Journals (Sweden)

Adriana Demathe

2010-04-01

Full Text Available Introdução: Recentemente o papilomavírus humano (HPV tem sido associado à carcinogênese oral. A metodologia empregada na detecção do vírus é uma das maiores causas observadas da grande variabilidade nas taxas de detecção do HPV. Objetivo: Este estudo comparou a sensibilidade de detecção do DNA do HPV em casos de carcinoma epidermoide de lábio utilizando a amplificação do DNA viral por reação em cadeia da polimerase (PCR ou nPCR. Material e método: Foram utilizadas 33 amostras provenientes de casos de carcinoma epidermoide de lábio. Para as extrações do DNA utilizou-se o sistema QIAamp DNA Mini Kit. Como controle interno utilizou-se o gene da b-globina. Das 33 amostras iniciais, 30 foram positivas para o gene b-globina, sendo utilizadas para detectar o DNA viral. Comparou-se a amplificação do DNA viral pelos métodos da PCR com os oligonucleotídeos MY09/MY11 e nPCR, empregando-se os pares de oligonucleotídeos iniciadores MY09/MY11 e, na segunda etapa, o par GP5+/GP6+. O controle positivo para a presença do DNA do HPV utilizado foi a linhagem de células HeLa e, como controle negativo, a mistura de amplificação sem DNA. A análise dos produtos de PCR e nPCR para HPV foi realizada por eletroforese em gel de poliacrilamida a 8%. Resultados: Utilizando-se o método da PCR, a amplificação do DNA do HPV foi constatada em dois casos. Com a nPCR foi verificada presença de DNA viral em 13 das 30 amostras. Conclusão: Com a utilização da nPCR, a detecção do HPV nos casos estudados aumentou mais de seis vezes.Introduction: Human papillomavirus (HPV has been currently associated with oral carcinogesis. The methodology applied in virus detection is one of the main reasons for the great variability observed in HPV detection. Objectives: This study compared HPV DNA detection efficiency in lip squamous cell carcinoma samples (SCC using viral DNA amplification by PCR or nPCR. Methods: Thirty three samples of lip squamous cell

Chemical Meningitis with Intracranial Tumours | De Klerk | South ...

African Journals Online (AJOL)

Two patients with intracranial epidermoid tumours who had a chemical meningitis as part of their clinical course, are described. The importance of recognising this as a presenting complaint is stressed. The pathogenesis and treatment are discussed.

The need of alkalinity determination in the characterization of rain; Necesidad de la determinacion de la alcalinidad en la caracterizacion de la lluvia

Energy Technology Data Exchange (ETDEWEB)

Pal Verma, Mahendra [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

1998-01-01

In this paper is presented the alkalinity determination of the carbonic species in the rain waters by the Gran titration method. The alkalinity values obtained by this method in low electric conductivity waters are fairly reliable. Also, the existing studies on the characterization of acid rains, are discussed. [Espanol] En este trabajo se presenta la medicion de la alcalinidad y la determinacion de las especies carbonicas en las aguas de lluvia por el metodo de la titulacion de Gran. Los valores de alcalinidad obtenidos por este metodo en las aguas de baja conductividad electrica son bastante confiables. Asimismo, se discuten los estudios existentes sobre la caracterizacion de la lluvia acida en la republica mexicana.

Brachytherapy of penis cancer: experience of the Gustave-Roussy Institute; Curietherapie des cancers de verge: experience de l'Institut Gustave-Roussy

Energy Technology Data Exchange (ETDEWEB)

Crevoisier, R. de; Wibault, P.; M' barek, B.; Gerbaulet, A.; Haie-Meder, C. [Institut Gustave-Roussy, 94 - Villejuif (France)

2006-11-15

The interstitial brachytherapy is a conservative treatment of epidermoid carcinomas of the penis under 4 centimeters and does not invade the erectile tissue. the great majority of recurrences is under control by a surgery treatment. (N.C.)

Proposed method for the hydraulic design of ski-jump energy dissipators in dam spillways considering the occurrence of scour holes downstream of the structure; Metodo propuesto para el diseno hidraulico de trampolines empleados como disipadores de energia en aliviaderos para presas, considerando la ocurrencia del cono de socavacion al pie del mismo

Energy Technology Data Exchange (ETDEWEB)

Pardo-Gomez, Rafael [Centro de Investigaciones Hidraulicas (Cuba)

2008-04-15

Ski-jump energy dissipators are widely used in hydraulic engineering because of their well-known effectiveness. Nevertheless, some uncertainty exits associated with the dimensions of the scour hole appearing downstream of the structure. This paper presents a new method for solving this problem. This method includes spillway stability checking as part of the design process and also stability checking of any other construction near the energy dissipation zone. [Spanish] Los disipadores de energia tipo trampolin tienen amplia utilizacion en la practica de la ingenieria hidraulica por su probada eficacia; sin embargo, su diseno esta sujeto a cierto grado de incertidumbre en cuanto a la prediccion de las dimensiones del cono de socavacion que habra de producirse aguas abajo de la estructura. En el presente trabajo se muestra un metodo novedoso, mediante el cual el autor soluciona el aspecto antes referido, toda vez que se incluye como parte del proceso de diseno la comprobacion de la estabilidad del propio aliviadero o de cualquier otra obra cercana a la zona de disipacion de energia.

Planning the expansion of electrical transmission networks with evolutionary programming; Planeacion de la expansion de redes de transmision electrica con programacion evolucionaria

Energy Technology Data Exchange (ETDEWEB)

Ceciliano Meza, Jose Luis

1997-12-31

In this work it is presented for the first time in the literature the solution of the problem of the planning the expansion of an electrical transmission network (PERTE) with the use of the Evolutionary Programming. The evolutionary programming is a stochastic method of optimization with similar characteristics to the generic algorithms, but different. During the development of this work it is shown what each one of these two heuristic methods of optimization consist of. Additionally, the main characteristics of other two heuristic methods known in the literature are described (Tabu Searching and Simulated Annealing). These two methods together with the genetic algorithms and decomposition of Benders have also been used to solve the problem of planning PERTE. The operation of the proposed algorithm of evolutionary programming was tested in two networks of electrical transmission. The first case of test is a system which is known in the literature. The second case is a representative system of the electrical transmission network of Central America. The results obtained improve all the results shown when applying different heuristic methods of optimization (genetic algorithms, simulated annealing and Tabu searching) to solve the same problem. [Espanol] En este trabajo se presenta por primera vez en la literatura, la solucion del problema de la planeacion de expansion de una red de transmision electrica (PERTE) con el uso de la Programacion Evolucionaria. La programacion evolucionaria es un metodo estocastico de optimizacion con caracteristicas similares a los algoritmos geneticos, pero diferente. Durante el desarrollo de este trabajo se muestra en que consiste cada uno de estos dos metodos heuristicos de optimizacion. Ademas, se describen las caracteristicas principales de otros dos metodos heuristicos conocidos en la literatura (busqueda Tabu y Recorrido Simulado). Estos dos metodos juntos con los algoritmos geneticos y descomposicion de Benders tambien han sido

MINIMUM BRACING STIFFNESS FOR MULTI-COLUMN SYSTEMS: THEORY

Directory of Open Access Journals (Sweden)

J. DARÍO ARISTIZÁBAL-OCHOA

2011-01-01

Full Text Available Se propone un metodo que determina la rigidez minima de arrostramiento requeridos por un sistema elastico de varias columnas para lograr condiciones de pandeo sin deriva entre pisos. Las ecuaciones que evaluan la rigidez minima requerida de los arrostramientos laterales y de torsion y la carga critica de pandeo ¡§arriostrada¡¨ correspondiente para cada columna del nivel de piso se obtienen utilizando las funciones de estabilidad modificadas. Se incluyen los siguientes efectos: 1 tipos de conexiones (rigidas, semirrigidas y simples, 2 la distribucion en planta de las columnas (es decir, la orientacion de la seccion transversal y la ubicacion del centro de gravedad de cada columna, 3 deformaciones por cortante a lo largo de cada columna mediante el metodo modificado propuesto por Haringx en 1948, y 4 distribucion de la carga axial entre las columnas (es decir, el patron de carga. Los efectos de las deformaciones axial y de torsion no estan incluidos. El metodo propuesto es aplicable a estructuras 2D y 3D con conexiones rigidas, semirigidas y simple. La formulacion se presenta en este documento se basa en un trabajo previo presentado por Aristizabal-Ochoa en 2007. Se demuestra que la rigidez minima de los arrostramientos laterales y de torsion requeridos por un sistema de varias columnas depende de: 1 la distribucion en planta las columnas; 2 la variacion en altura y propiedades de la seccion transversal de las columnas; 3las rigideces a flexion y a cortante de cada columna; 4 el patron de cargas en el sistema de columnas; 5 la falta de simetria (en el patron de carga, en la disposicion de las columnas, tamanos de las columnas, y sus alturas que hacen que el pandeo combinado de torsion y flexion lateral pueden reducir la capacidad de pandeo critico de la estructura en su conjunto; y 6 las condiciones de apoyo y restricciones en el extremo superior de las columnas. El metodo propuesto se limita a sistemas multi-columna con columnas elasticas y

A green approach toward quinoxalines and bis-quinoxalines and their biological evaluation against A431, human skin cancer cell lines.

Science.gov (United States)

Bandyopadhyay, Debasish; Cruz, Jessica; Morales, Liza D; Arman, Hadi D; Cuate, Erica; Lee, Young S; Banik, Bimal K; Kim, Dae J

2013-08-01

The objective of this study was to develop a practical green procedure to synthesize quinoxalines and bis-quinoxalines and evaluate their inhibitory effects on the viability of A431 human epidermoid carcinoma cells. A series of quinoxaline and bis-quinoxaline derivatives have been designed and synthesized following a microwave-assisted and bismuth nitrate-catalyzed eco-friendly route. A detailed comparison has been made between microwave-induced protocol with the reactions occurred at room temperature. The structure of the compounds have been elucidated by various spectroscopic methods and finally confirmed by x-ray crystallographic analyses. Two quinoxaline derivatives, compounds 6 and 12 have demonstrated inhibitory effects on the viability of A431 human epidermoid carcinoma cells when compared with HaCaT nontumorigenic human keratinocyte cells. Notably, compound 6 inhibits Stat3 phosphorylation/activation in A431 skin cancer cells.

Reinke Edema: Watch For Vocal Fold Cysts.

Science.gov (United States)

Tüzüner, Arzu; Demirci, Sule; Yavanoglu, Ahmet; Kurkcuoglu, Melih; Arslan, Necmi

2015-06-01

Reinke edema is one of the common cause of dysphonia middle-aged population, and severe thickening of vocal folds require surgical treatment. Smoking plays a major role on etiology. Vocal fold cysts are also benign lesions and vocal trauma blamed for acquired cysts. We would like to present 3 cases with vocal fold cyst related with Reinke edema. First case had a subepidermal epidermoid cyst with Reinke edema, which could be easily observed before surgery during laryngostroboscopy. Second case had a mucous retention cyst into the edematous Reinke tissue, which was detected during surgical intervention, and third case had a epidermoid cyst that occurred 2 months after before microlaryngeal operation regarding Reinke edema reduction. These 3 cases revealed that surgical management of Reinke edema needs a careful dissection and close follow-up after surgery for presence of vocal fold cysts.

De una fimosis a la amputación total del pene From phymosis to total amputation of the penis

Directory of Open Access Journals (Sweden)

Lourdes Santana Sarrhy

2007-09-01

Full Text Available El caso que presentamos es el de un paciente de 53 años que, al no tratarse adecuadamente una fimosis, presentó un carcinoma epidermoide de pene y fue necesario realizar una amputación total de este órgano. Es sabido que en la actualidad ese tipo de enfermedad es prevenible y que su aparición se debe a una higiene genital inadecuada relacionada con la presencia de fimosis o prepucio redundanteThe case of a 53 years-old patient, who did not look for adequate treatment for phymosis and developed epidermoid carcinoma of the penis leading to the total amputation of this organ, was presented in this paper. It is known that this type of disease is preventable at present and that it occurs due to phymosis or redundant foreskin-related poor genital hygiene

Development of a chromatographic method for the study of the stability and compatibility of Mexican fuel oils; Desarrollo de un metodo cromatografico para el estudio de estabilidad y compatibilidad de combustoleos mexicanos

Energy Technology Data Exchange (ETDEWEB)

Blass Amador, Georgina; Panama Tirado, Luz Angelica [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

1992-11-01

compatibility of fuel oil mixes. [Espanol] En Mexico, la mayoria de la energia electrica producida proviene del uso de combustibles residuales pesados conocidos como combustoleos los cuales han sufrido disminuciones en la calidad debido a una combinacion de factores, entre los que destaca el de los cambios en el proceso de refinacion. Es necesario desarrollar metodos que sean capaces de indicar la inestabilidad (formacion de sedimento o incremento en viscosidad durante el almacenamiento o calentamiento) o incompatibilidad (formacion de sedimento al mezclar dos o mas) de los combustoleos utilizados en las centrales termoelectricas. El objetivo de este trabajo fue el desarrollar una prueba alternativa para el estudio de la compatibilidad y/o estabilidad de combustoleos mexicanos empleando cromatografia de liquidos de alta resolucion (CLAR) y asi poder determinar aspectos estructurales del combustoleo que determinan su estabilidad. Dado que la formacion de sedimentos ocurre cuando el poder disolvente del combustible es inadecuado para mantener los asfaltenos en solucion, es importante conocer la medida del poder disolvente o aromaticidad del diluyente; asi pues, la primera parte de este trabajo se centro en la determinacion del perfil de compuestos aromaticos de los diluyentes de los combustoleos, la otra parte se dedico a la determinacion del perfil de distribucion de los pesos moleculares de los asfaltenos presentes en los combustoleos. Los perfiles de la fraccion aromatica, asi como los de distribucion de pesos moleculares se determinaron empleando cromatografia de liquidos, en la que se empleo una variedad de columnas y de disolventes. Se efectuo una combinacion de pruebas de rutina tales como contenido de asfaltenos, equivalencia de tolueno, viscosidad, etcetera con el fin de obtener correlaciones con el metodo cromatografico desarrollado. En este articulo se discute solo la seccion correspondiente a la obtencion del perfil de contenidos de aromaticos de los combustoleos. Se

Description of new techniques on interstitial brachytherapy in head and neck (oral cavity)

International Nuclear Information System (INIS)

Marsiglia, H.

1990-01-01

Several case of epidermoid carcinomas in buccal cavity treated by brachytherapy associated with others therapeutic techniques are described, including the results using different therapeutical methods and the clinical and technical parameters considered on the evolution of the disease. (C.G.C.)

Cromatografía de capa fina

OpenAIRE

Blay Llinares, Gonzalo

2011-01-01

Este video explica como preparar y llevar a cabo un análisis mediante cromatografía de capa fina. Se enseña cómo cortar el cromatofolio, preparar las disoluciones de las muestras, depositarlas en el cromatofolio , la elución de las muestras y el revelado del cromatograma a la luz ultravioleta y con un revelador químico.

Solarização do solo com filmes plásticos com e sem aditivo estabilizador de luz ultravioleta Soil solarization with plastic films with and without UV light stabilizers

Directory of Open Access Journals (Sweden)

Benedito C. Barros

2004-06-01

Full Text Available Visando auxiliar na escolha de filmes plásticos adequados para a solarização, dois experimentos foram instalados em Mogi das Cruzes e Piracicaba (SP, em janeiro e fevereiro de 2000. Três tipos de filmes plásticos transparentes de polietileno de baixa densidade (PEBD, com 100 mm de espessura, produzidos pela empresa Nortène Plásticos Ltda., foram testados: a FES, filme estufa super tricarpa super aditivado, com aditivo estabilizador de luz ultravioleta (baseado em aminas estericamente impedidas; b FSOL, filme para solarização produzido com metade da quantidade do mesmo aditivo e c LT, lona plástica transparente, sem aditivo, além de uma testemunha sem cobertura plástica, em delineamento de blocos casualizados, com quatro repetições. Após a retirada dos plásticos foi conduzida uma safra de alface em ambos os locais. Foi realizada análise química dos solos e das plantas colhidas, além de avaliada a infestação por plantas daninhas e a massa fresca das plantas colhidas. Em Piracicaba também foram realizadas análises microbiológicas dos solos e determinada a viabilidade de Pythium aphanidermattum. Em Mogi das Cruzes foi avaliada a incidência de podridão de esclerotínia, causada por Sclerotinia minor. As temperaturas médias registradas, a 10 cm de profundidade, nos solos sob os diferentes filmes plásticos foram semelhantes, de 44-41ºC nos solos solarizados e de 33,9-30,2ºC nos solos não solarizados de Piracicaba e Mogi das Cruzes, respectivamente. Detectou-se aumento na massa fresca das plantas colhidas nas parcelas solarizadas, de 49% em Piracicaba e 24% em Mogi das Cruzes, independente do plástico testado. Nos dois locais também houve drástica redução na infestação por plantas daninhas nas áreas solarizadas. Nas análises microbianas não foram verificadas alterações na liberação de CO2, no carbono da biomassa microbiana, no quociente metabólico e no número total de bactérias. O número de fungos foi

Midface swelling reveals nasofrontal dermal sinus

International Nuclear Information System (INIS)

Houneida, Zaghouani Ben Alaya; Manel, Limeme; Latifa, Harzallah; Habib, Amara; Dejla, Bakir; Chekib, Kraiem

2012-01-01

Nasofrontal dermal sinuses are very rare and generally occur in children. This congenital malformation can be revealed by midface swelling, which can be complicated by local infection or neuromeningitis. Such complications make the dermal sinus a life-threatening disease. Two cases of nasofrontal dermal sinuses are reported in this work. The first case is an 11-month-old girl who presented with left orbitonasal soft tissue swelling accompanied by inflammation. Physical examination found fever, left orbitonasal thickening, and a puncture hole letting out pus. Computed tomography revealed microabscesses located at the left orbitonasal soft tissues, a frontal bone defect, and an intracranial cyst. Magnetic resonance imaging showed the transosseous tract between the glabella and the brain and affirmed the epidermoid nature of the intracranial cyst. The second case is a 7-year-old girl who presented with a nasofrontal non-progressive mass that intermittently secreted a yellow liquid through an external orifice located at the glabella. MRI revealed a cystic mass located in the deep layer of the glabellar skin related to an epidermoid cyst with a nasofrontal dermal sinus tract. In both cases, surgical excision was performed, and pathological confirmation was made for the diagnoses of dermal sinuses. The postoperative course was favorable. Through these cases, the authors stress the role of imaging methods in confirming the diagnosis and looking for associated cysts (dermoid and epidermoid) to improve recognition of this rare disease. Knowledge of the typical clinical presentations, imaging manifestations, and most common sites of occurrence of this malformation are needed to formulate a differential diagnosis.

Design and construction of a live insulator washing system for transformers; Diseno y construccion de un sistema de lavado en vivo para los aisladores de transformadores

Energy Technology Data Exchange (ETDEWEB)

Lizama-Camara, Y.A. [Universidad Veracruzana, Veracruz (Mexico)]. E-mail: yahir_lizama@ieee.org; Mendieta-Antunez, J.A.; Blanco-Brisset, E. [Industrias IEM, Tlalnepantla, Estado de Mexico (Mexico)]. E-mail: unamanu@hotmail.com; Olivares Galvan, J.C.; Escarela-Perez, R. [Universidad Autonoma Metropolitana, Unidad Azcapotzalco, Mexico, D.F. (Mexico)]. E-mails: jolivare_1999@yahoo.com; r.escarela@ieee.org

2012-04-15

Through the electrical industry history there have been developments of different cleaning methods to avoid the insulators flashover s due to pollution. This paper describes the principal cleaning methods applicable to transformers insulators, emphasizing the high pressure fixed-type live insulator washing method, which was applied for cleaning the insulators of 900 MVA transformer bank of the Laguna Verde power plant localized at the state of Veracruz in Mexico. We propose a transformer insulator cleaning methodology, which identifies the main variables to take into account (the voltage level of the transformers, the pollution level of the insulators, determination of the optimal wash time, the amount of water, the optimal pressure of water jet, the maximum conductivity of the water and the wind velocity), reference values are given for these variables. In addition, we present an economic cost analysis when applying a method of this kind in an electric substation. [Spanish] A lo largo de la historia de la industria electrica se han desarrollado diferentes metodos de limpieza para evitar las fallas de los aisladores de los transformadores debido a la contaminacion. Este articulo describe los principales metodos de limpieza aplicables a los aisladores de transformadores, enfatizando el sistema de lavado en vivo tipo fijo con agua a alta presion, metodo que fue aplicado para realizar la limpieza de los aisladores en el banco de transformadores de 900 MVA de la central electrica Laguna Verde, ubicada en el estado de Veracruz, en Mexico. Se propone una metodologia para la limpieza de los aisladores de transformadores, donde se identifican las principales variables a tomar en cuenta (el nivel de tension de los transformadores, nivel de contaminacion de los aisladores, determinacion del tiempo optimo de lavado, cantidad de precipitacion de agua, presion optima del chorro de agua, maxima conductividad del agua y las velocidades de los vientos) y se dan valores de

Male Urethral Diverticulum Having Multiple Stones

African Journals Online (AJOL)

muscle fibers in their wall, commonly encountered in adults, and involve the posterior urethra. Differential diagnosis for UD includes syringoceles (cystic dilatation of the Cowper's gland), sequestration cysts, epidermoid and epithelial inclusion cysts. Male Urethral Diverticulum Having Multiple Stones. Mohanty D, Garg PK, ...

Browse Title Index

African Journals Online (AJOL)

... hemorrhage mimicking a pneumopathy: a rare complication of dual antiplatelet therapy for ST elevation myocardial infarction, Abstract PDF. Sara Oualim, Charafeddine Ait Elharda, Dounia Benzeroual, Mustapha El Hattaoui. Vol 12, No 1 (2012), Pulmonary epidermoid carcinoma in a patient with acromegaly: a rare entity ...

Clinical cases

International Nuclear Information System (INIS)

Servente, L.

2012-01-01

This presentation is about clinical cases and the contribution of the PET - CT Fag application in the diagnosis and treatment of different types of cancer. The cases presented were: neck diseases, epidermoid carcinoma, liver damage and metastasize, lymphoma, thrombosis, colonic cancer and lung disease

Fundamentos del metodo cientifico

Directory of Open Access Journals (Sweden)

Badii, M. H.

2004-01-01

Full Text Available El objetivo de esta obra no radica en realizar una búsqueda exhaustiva de la literatura en el tema, sino, sentar las bases del método científico, notando los aspectos filosóficos e éticos de la ciencia. Se presentan los conceptos y definiciones fundamentales relacionados con la metodología de la investigación científica. Se maneja el concepto de la toma de los datos válidos como un requisito básico en cualquier trabajo científico. Se pone a disposición del lector un modelo denominado el ECOEE que es una herramienta poderosa para establecer puntos de comparación e discusión entre los resultados de diferentes trabajos científicos. Finalmente, ofrece unas sugerencias de que hacer o no hacer en cuanto a realizar un trabajo de investigación.

Mathematics and history: history and analysis epistemology: from exhaustion method to defined integral

Directory of Open Access Journals (Sweden)

Mario Mandrone

2015-06-01

Full Text Available The creation of the calculation (differential, in the terminology of Leibniz, bending in that of Newton is the event that, in the second half of the seventeenth century, marked, in a sense, the transition from classical to modern mathematics. The aim of this work is a historical analysis of the rigor and epistemological question and the "metaphysics" of calculus that takes account of the methods of the ancient (eg. Of Archimedes' method of exhaustion, as well as interpretations of Leibniz and Newton and their successors. The problem of searching for a sure foundation on which to base the calculus, glimpsed by D'Alembert in the theory of limits and taken up by Lagrange to the theory of infinite series, and that the derivative functions, found in Cachy the pioneer of a new way to seek rigor in analysis. The Cauchy setting will be tightened by Weierstrass in the second half of the 800 with the definition of limit, with the epsilon-delta method, which in turn is based on definitions concerning the real numbers. In this sense we speak of "arithmetisation" analysis.         Matematica e storia: storia ed epistemologia dell’analisi: dal metodo  di esaustione  all’integrale  definito La creazione del calcolo (differenziale, nella terminologia leibniziana flessionale in quella di Newton è l’evento che, nella seconda metà del seicento, ha segnato, in un certo senso, il passaggio dalla matematica classica a quella moderna. Obiettivo del presente lavoro è una analisi storica ed epistemologica della questione del rigore e della “metafisica” del calcolo infinitesimale che tenga conto dei metodi degli antichi (ad es.  del metodo di esaustione di Archimede, nonché delle interpretazioni di Leibniz e Newton e dei loro successori. Il problema della ricerca di un fondamento sicuro su cui basare il calcolo infinitesimale, intravisto da D’Alembert nella teoria dei limiti e ripreso da Lagrange con la teoria delle serie infinite e quella delle

Development of sialons colloidally processed in aqueous medium

Science.gov (United States)

Pereira, Catarina Alexandra Goncalves

Desenvolveu-se um novo metodo de processamento coloidal em meio aquoso para consolidar cerâmicos de ?-Y-SiAlON, os quais foram sinterizados por prensagem isostatica a quente (HIP) e por spark plasma sintering (SPS). Preparou-se com sucesso uma suspensao aquosa de pos precursores de YSiAlON (Si3N4, Al2O3, Y2O3 e AlN), temporariamente estavel, usando Dolapix PC21 como dispersante, permitindo a fabricacao de pos granulados pela tecnica de aspersao-congelamento-liofilizacao e a consolidacao de corpos em verde por enchimento por barbotina. Avaliou-se o efeito do excesso de oxigenio introduzido pelo processamento aquoso no desenvolvimento microestrutural e nas propriedades mecânicas. Os corpos de Y-SiAlON consolidados por enchimento por barbotina e sinterizados por HIP a 1800ºC apresentaram microestruturas e propriedades mecânicas similares a corpos consolidados por prensagem a seco. Estes materiais exibiram densificacao completa, dureza Vickers maxima de 2003 e tenacidade a fractura (metodo SEVNB) maxima de 5.20 MPam1/2. Foi ainda possivel estabelecer uma relacao estreita entre o aumento do conteudo em oxigenio das amostras sinterizadas e a diminuicao da tenacidade a fractura. Na tentativa de melhorar a tenacidade a fractura dos materiais, procedeu-se a incorporacao nas suspensoes de sementes de Ca-?-SiAlON de geometria alongada produzidas por sintese por combustao, adicionadas como agentes de reforco. A sintese por combustao realizada em larga escala (cargas ate 1 kg) nao produziu efeitos negativos obvios nos produtos da reaccao. Investigara-se os efeitos da adicao de 5 % em peso de sementes nas propriedades mecânicas e no desenvolvimento microestrutural de amostras densificadas por HIP. Em comparacao com os materiais sem sementes, a tenacidade a fractura (metodo SEVNB) aumentou 13%, mas a dureza Vickers resultou 14,5% inferior. A sinterizacao por SPS permitiu obter densificacao completa a temperaturas tao baixas como 1600ºC a partir dos pos granulados de Y

Accessibilità e fruibilità del patrimonio architettonico: occasioni per una sostenibilità “sociale” del recupero

Directory of Open Access Journals (Sweden)

Alessandro Greco

2012-12-01

Full Text Available Il tema dell’accessibilità e della fruibilità del patrimonio storico – architettonico sta assumendo sempre più rilevanza nel contesto nazionale, e in quello europeo più in generale, anche per le importanti funzioni che normalmente vengono inserite in contenitori edilizi dall’elevato valore culturale e documentale, collocati spesso nel centro storico delle città oppure in aree di elevato pregio ambientale.Il contributo propone riflessioni di carattere generale sull’importanza “sociale” dell’accessibilità al patrimonio edilizio storico e offre spunti per un approccio alla progettazione dell’accessibilità secondo un metodo consapevole della complessità del tema, partecipato e multidisciplinare. Il testo si completa con l’illustrazione di due ricerche applicate (una alla scala urbana e una alla scala edilizia sviluppate secondo tale metodo.

Colorectal cancer: before and after PET-CT; Cancer colorrectal: antes y despues de PET-TC

Energy Technology Data Exchange (ETDEWEB)

San Roman, Jose [Hospital Italiano, Buenos Aires (Argentina). Servicio de Diagnostico por Imagenes

2008-07-01

The author makes reference to the fundamental and growing role of images in the detection, localization, staging and control in colorectal cancer therapy. He points out the main reasons why the combined method PET-CT has meant to a great progress in diagnostic imaging and compares its diagnostic capacity and cost-benefit with other methods. Also, he makes a brief review of some technical aspects. [Spanish] El autor senala el rol central y creciente de las imagenes para la deteccion, localizacion, estadificacion y control del tratamiento del CCR. Menciona las razones principales por las que el metodo combinado PET-TC ha significado un progreso mayor para el diagnostico por imagenes y compara su capacidad diagnostica y costo-beneficio con los metodos establecidos. Tambien hace un repaso breve de algunos aspectos tecnicos.

Solitary pulmonary nodule: radiologic features and diagnostic approach; Nodulo pulmonar solitario: caracteristicas radiologicas y abordaje diagnostico

Energy Technology Data Exchange (ETDEWEB)

Rodriguez Cambronero, Luis Enrique

2012-07-01

A literature review is conducted on the solitary pulmonary nodule, to determine the diagnostic methods and specific characteristics. The diagnostic methods used have been: chest radiography, computed tomography, positron emission tomography and magnetic resonance imaging. The radiological features are defined: location, size, definition of contours or edges (margins), densitometric and attenuation characteristics, cavitation, air bronchogram, growth, doubling time, satellite nodules, nutrient vessels [Spanish] Una revision bibliografica es realizada sobre el nodulo pulmonar solitario, para determinar los metodos de diagnostico y caracteristicas especificas. Los metodos de diagnostico utilizados han sido: la radiografia de torax, tomografia computarizada, tomografia por emision de positrones y resonancia magnetica. Las caracteristicas radiologicas son definidas: localizacion, tamano, definicion de los bordes o contornos (margenes), caracteristicas densitometricas y de atenuacion, cavitacion, broncograma aereo, crecimiento, tiempo de duplicacion, nodulos satelite, vasos nutrientes.

Clinical status of carboplatin.

Science.gov (United States)

Canetta, R; Franks, C; Smaldone, L; Bragman, K; Rozencweig, M

1987-07-01

Carboplatin, a cisplatin derivative, shows promise of being an effective weapon against ovarian, cervical, and small-cell lung cancer, as well as epidermoid cancer of the head and neck, with fewer toxic effects than cisplatin. It has successfully completed phase III investigation and clinical trials continue.

Chimica-fisica primo anno

CERN Document Server

Bianchi, U; Volta, L

Termodinamica ; cenni sulla costituzione della materia ; il metodo statistico ; le statistiche di Boltzmann-Maxwell, Bose-Einstein e Fermi-Dirac ; studio termodinamico e statistico del gas perfetto e delle miscele gassose ; i solidi cristallini ; le reazioni chimiche.

Pathology associated with inhaled plutonium in beagles

International Nuclear Information System (INIS)

Dagle, G.E.; Park, J.F.; Weller, R.E.; Ragan, H.A.; Stevens, D.L.

1986-01-01

The pathology associated with the inhalation of plutonium was studied in beagle dogs given a single exposure to aerosols of 239 PuO 2 , 238 PuO 2 , or 239 Pu(NO 3 ) 4 . The temporal-spatial relationships between plutonium deposition and the development of lesions in dogs were evaluated up to 11 years, 8 years, or 5 years, respectively, after exposures, resulting in initial lung burdens ranging from ∼2 to ∼5500 nCi. Exposure of the lung to high dose levels produced a spectrum of progressively more severe morphological changes, ranging from radiation pneumonitis to fibrosis. Lung tumors occurred at exposure levels that did not result in early death from radiation pneumonitis or fibrosis. Bronchiolar-alveolar carcinomas, papillary adenocarcinomas, epidermoid carcinomas, and combined epidermoid and adenocarcinomas were observed. Sclerosing tracheobronchial lymphadenitis, radiation osteodystrophy, osteosarcoma, and hepatic adenomatous hyperplasia were the principal extrapulmonary lesions resulting from translocation of plutonium. 15 refs., 2 tabs

MALIGNANT TRANSFORMATION OF EROSIVE ORAL LICHEN PLANUS

Directory of Open Access Journals (Sweden)

Siti Chumaeroh

2006-04-01

Full Text Available Lichen planus is a relatively common inflammatory disorder which may have cutaneous and or mucosal manifestation. The malignant potential of oral lichen planus is still debatable. Some authors are sceptical about the premalignant nature of the disease, while other investigators have reported that malignant transformations occur in 1-10% of the cases. The aim of this study is to report a case of erosive lichen plans which shows malignant transformation of histopathologic examination. A man of 39 years old visited the Dental Department or Kajradi's Hospital with pain symptoms of the palate, buccal and gingival mucosa on both sides for 6 months. The physical examination shows the white lesion with striae configuration and pain, red erosive area inside the palate extends to the buccal mucosa and the gingival mucosa. The suspect diagnosis is erosive lichen planus, but the histopathologic examination shows epidermoid carcinoma. It is concluded that erosive oral lichen planus has the potential to transform into epidermoid carcinoma.

[Giant splenic cyst in a teenager girl: Case report].

Science.gov (United States)

Martínez Torres, Beatriz; Medina García, Manuel; Zafra Anta, Miguel Ángel; García Muñoz-Najar, Alejandro José; Tardío Dovao, Juan C

2017-06-01

Giant nonparasitic splenic epidermoid cysts are relatively uncommon. These lesions can lead abdominal pain, but most of then are asymptomatic, and they are discovered incidentally. We report a 13-y old female with a giant splenic epidermoid cystic, given the special interest of diagnostic and therapeutic decision-making of this rare entity. A 13-y old female with clinical history of abdominal pain since the last two months. On physical examination a firm, tender mass was palpable in left hypochondrium. Diagnosis of a large cystic splenic mass was made based on ultrasound and abdominal computed tomography scan. Splenectomy was performed, and histopathological-immunohistochemistry studies revealed findings suggestive of primary epithelial cyst. The post-operative clinical course was satisfactory and uneventful. Treatment of giant nonparasitic splenic cysts is surgical. Preserve splenic parenchyma must be the aim in an individualized decision-making. The different types of surgical modalities will be according to the diagnosis and clinical situation (cyst size, age, comorbidities).

Extensions of the techniques for the accelerated unspecific isotopic labelling of organic compounds; Applications nouvelles des techniques accelererees du marquage non specifique de composes organiques; Rasprostranenie metodov uskoreniya mecheniya nespetsifichnymi izotopami organicheskikh slozhnykh soedinenij; Nuevas aplicaciones de las tecnicas de marcacion inespecifica acelerada de compuestos organicos

Energy Technology Data Exchange (ETDEWEB)

Ghanem, N A [National Research Centre, El-Dokki, Cairo (Egypt); Westermark, T [Division of Physical Chemistry, Royal Institute of Technology, Stockholm 70 (Sweden)

1962-03-15

marcar, y citar ejemplos en los que este procedimiento se ha empleado con exito. Las diversas tecnicas se basan en el uso de descargas de microondas y de ondas hertzianas, descargas luminiscentes producidas por corriente continua, o alterna, o sencillamente rayos ultravioleta. Se han obtenido cantidades considerables de productos purificados con actividades superiores a 100 mcuries/g. Los tiempos de exposicion a las descargas son del orden de un minuto, y en la mayoria de los casos se observo poca descomposicion. Los autores calcularon el rendimiento energetico alcanzado en estos metodos de marcacion y lo comparan con el correspondiente a las radiaciones ionizantes empleadas por Wilzbach y otros investigadores; tambien dan los valores de G para la sustitucion isotopica. Existen pruebas de que la marcacion del poliestireno se produce en virtud de una reaccion atomo-molecula. (author) [Russian] Tsel'yu nastoyashchego doklada yavlyaetsya rassmotrenie novykh sposobov uskoreniya reaktsii mezhdu radioaktivnym gazom i materialom misheni, podlezhashchim mecheniyu, a takzhe privedenie primerov uspeshnykh sluchaev. Ehti metody vklyuchayut ispol'zovanie razryadov mikrovoln i radiovoln, tleyushchikh razryadov pod vozdejstviem istochnikov postoyannogo ili peremennogo tokov, ili prosto radiatsii ul'trafioletovykh luchej. Byla dostignuta udel'naya aktivnost', dokhodyashchaya do 100 mikrokyuri na gramm, v znachitel'nykh kolichestvakh ochishchennogo produkta. Vremya vozdejstviya razryada bylo poryadka odnoj minuty, i vo mnogikh sluchayakh razlozhenie bylo chrezvychajno ogranichennym. Dayutsya podschety ehffektivnosti ispol'zovaniya ehnergii dlya proizvodstva mecheniya ehtimi metodami po sravneniyu s zatratoj dlya toj zhe tseli ehnergii ioniziruyushchego izlucheniya, ispol'zuemoj Vil'tsbakhom i dr. ; krome togo, ukazyvayutsya znacheniya radiatsionnokhimicheskogo vykhoda G dlya zameny izotopov. Est' ukazaniya na to, chto pri mechenii polistirola mekhanizm opredelyaetsya reaktsiej atom

An Appraisal of Analytical Methods for Plutonium and their Applications to the Analysis of Nuclear Materials; Evaluation des Methodes Analytiques de Dosage du Plutonium et de Leur Application a l'Analyse des Matieres Nucleaires; Otsenka analiticheskikh metodov opredeleniya plutoniya i ikh primenenie dlya analiza yadernykh materialov; Metodos Analiticos de Determinacion del Plutonio y su Empleo en el Analisis de Materiales Nucleares

Energy Technology Data Exchange (ETDEWEB)

Milner, G. W.C.; Phillips, G. [Atomic Energy Research Establishment, Harwell, Berks. (United Kingdom)

1966-02-15

respectifs de la dissolution dans des melanges d'acides mineraux courants et de la dissolution faisant appel a des procedes de fusion, avec des exemples a l'appui. Les auteurs decrivent aussi les procedes utilises et les resultats obtenus, pour l'analyse des alliages Pu-U, Pu-Ce-Co et Pu-U-Mo, des oxydes et carbures de Pu-U, et des cermets de carbure de Pu-U contenant Fe, Mo et Cr. Ces matieres sont l'aboutissement de recherches metallurgiques destinees a mettre au point des combustibles nucleaires. (author) [Spanish] Para determinar el contenido de plutonio de los materiales nucleares existen diversos metodos. Si se trata de cantidades del orden del miligramo se pueden emplear la espectrofotometria diferencial por el color del Pu (III), la gravimetria basada en el PuO2{sub ,} si recuento gamma y metodos de oxidorreduccion como las valoraciones potenciometricas o amperimetricas y la culombiometria de potencial controlado. Si se trata de microgramos son preferibles el recuento alfa, la dilucion isotopica o las tecnicas polarograficas. Teniendo en cuenta que unos metodos son mas adecuados que otros para ciertos tipos de muestra, el analista tiene que resolver un dificil problema de seleccion a fin de obtener ios mejores resultados posibles. Los autores exponen las ventajas y las limitaciones puestas de manifiesto por los anos de experiencia en la A.E.R.E. y formulan observaciones acerca de la exactitud y la precision de los metodos, su sensibilidad y otras cuestiones de especial interes. Como algunos de esos metodos exigen la separacion previa del plutonio, los autores estudian el empleo de las tecnicas de intercambio anionico y de cromatografia en fase inversa, y en particular su conveniencia para el analisis de muestras radiactivas. Examinan los muchos problemas que han surgido al analizar por estos metodos, aleaciones, productos ceramicos y cermets de plutonio en diversos sistemas que contenian uranio, torio, hierro, cromo, molibdeno, cerio y cobalto. La memoria trata

African Journal of Neurological Sciences 2013 - Vol. 32, No 1 http ...

African Journals Online (AJOL)

Service de Neurochirurgie, Hôpital Avicenne, Rabat. 2. Service de neuroradiologie, Rabat, Royaume du Maroc. Mots clés : Epidermoïde - Intra médullaire - IRM - Kyste - Moelle spinale. Keywords: Cyst - Epidermoid - Intramedullary -Medullary spinal -MRI. RESUME. Introduction. Les kystes épidermoïdes sont des tumeurs ...

Data Evaluation Problems in the Pulsed Neutron Source Method; Problemes d'Evaluation des Donnees dans les Applications de la Methode de la Source Pulsee; Problemy otsenki dannykh pri primenenii metoda istochnika impul'snykh nejtronov; Problemas de Evaluacion de Datos en el Metodo de la Fuente de Neutrones Pulsados

Energy Technology Data Exchange (ETDEWEB)

Pal, L.; Bod, L.; Szatmary, Z. [Central Research Institute for Physics, Hungarian Academy of Sciences, Budapest (Hungary)

1965-08-15

moyen de transport dans de nombreuses matieres hydrogenees. (author) [Spanish] Desde hace mas de diez anos se viene empleando el metodo de los neutrones pulsados para determinar los parametros de difusion de los neutrones termicos. Este metodo ha resultado especialmente idoneo para el estudio de los moderadores hidrogenados. Los autores dan los resultados de las mediciones hechas en agua, benceno, tolueno, xileno, ciclohexano, n-hexano y difenilo, y examinan los metodos para evaluar con el minimo error los parametros de difusion de interes partiendo de los datos obtenidos en las mediciones. Se examina detenidamente, tanto en el plano teorico como en el experimental, el efecto de tiempo de vuelo que se manifiesta por razones tecnicas cuando se investigan moderadores a elevadas temperaturas, y que influye en el valor de la constante de desintegracion, y se exponen las condiciones geometricas en que se ha de operar para obtener resultados satisfactorios. Los autores determinan tambien el efecto que sobre la constante de desintegracion ejerce el tiempo muerto del detector neutronico y del amplificador, y demuestran que es despreciable cuando [i(t) {tau}]{sup 2} << 1, siendo i/t/dt el numero de neutrones detectados en el intervalo de tiempo/t, t + dt/, y {tau} el tiempo muerto. Se evaluo la constante de desintegracion empleando el metodo de la maxima probabilidad. Para determinar inequivocamente la funcion de probabilidad, se eligio un analizador multicanal que acumulaba como maximo una sola senal por ciclo de analisis y por canal. Se comprobo que la incorporacion del parametro caracteristico del fondo a la funcion de probabilidad tiene primordial importancia. Los parametros de la funcion de maxima probabilidad se evaluaron en una calculadora aplicando el metodo de iteracion de Newton. Cuando no se tiene debidamente en cuenta el fondo, este puede causar una mayor contaminacion aparente de armonicos, la cual, a su vez, puede interpretarse como un fondo aparente. Por ello es

Case report

African Journals Online (AJOL)

ebutamanya

India. Key words: Dermoid, epidermod, gardner´s syndrome, teratoid. Received: 28/02/2016 - Accepted: 14/03/2016 - Published: 25/04/2016. Abstract. Epidermoid cysts are quite rare in the head and neck region. They present as an asymptomatic swelling. The differential diagnosis of these lesions include dermoid cyst ...

SOBREVIVÊNCIA DA MOLÉCULA ORGÂNCIA CH3OH EM REGIÕES DE ESTRELAS JOVENS

Directory of Open Access Journals (Sweden)

Will Robson Monteiro Rocha

2016-11-01

Full Text Available A molécula de CH3OH é uma das espécies orgânicas mais abundantes no meio interestelar e importante precursor de espécies pré-bióticas. Nesse trabalho estudamos sua sobrevivência em um cenário típico de estrela jovem, na presença de um campo de radiação ultravioleta (UV entre 91.2 – 205 nm. Para isso usamos o código de transferência radiativa RADMC-3D para calcular os perfis de densidade e intensidade média de fótons em toda parte do modelo. Através desses resultados, usamos a seção de choque de destruição do CH3OH na região do ultravioleta para calcular sua taxa de fotodissociação e tempo de meia vida. Concluímos que no interior do disco, a molécula pode sobreviver intacta e ser liberada para a fase gasosa por processos não-térmicos. Porém no envelope, a fotodissociação é predominante, podendo formar espécies como HCOOCH3, HOCH2CHO e CH3CH2OH.

Un matrimonio conveniente: el género y la educación

Directory of Open Access Journals (Sweden)

Sandra Araya Umaña

2003-01-01

Full Text Available En este artículo se presenta una revisiónde literatura acerca de la relación entre la radiaciónsolar y las lesiones de la piel. Se sabe que una partede la población se expone diariamente, y a veces du-rante muchas horas, a la radiación ultravioleta de losrayos solares. Sin embargo, por desconocimiento o pornegligencia, muchas personas sufren de lesiones porla exposición aguda o crónica a los rayos solares. EnCosta Rica, las lesiones relacionadas con la exposi-ción al sol son comunes; solamente durante el trieniode 1994 a 1996, el cáncer de piel fue el de mayor inci-dencia entre las mujeres y el segundo entre los hom-bres. Se ha llegado a determinar que el riesgo paraadquirir cáncer de piel aumenta si se poseen ciertascaracterísticas fenotípicas, como por ejemplo, pielblanca, cabello color rubio o rojo, y ojos color verde oazul. Aún queda por determinar la posible asociaciónentre la exposición a los rayos ultravioleta en perso-nas que se exponen diariamente durante largos perío-dos de tiempo a los rayos solares, como por ejemplo loseducadores físicos y los deportistas

Initial temperature distribution in Los Humeros, Mexico, geothermal field; Distribucion de temperatura inicial en el campo geotermico de Los Humeros, Puebla

Energy Technology Data Exchange (ETDEWEB)

Garcia, A; Arellano, V; Aragon, A; Barragan, R.M; Izquierdo, G [Instituto de Investigaciones Electricas, Temixco, Morelos (Mexico); Pizano, A [Comision federal de Electricidad, Los Humeros, Puebla (Mexico)

2000-12-01

The initial formation temperatures surrounding 40 wells from the Los Humeros geothermal field are presented. These temperatures were estimated using the Horner and the sphere methods. A brief discussion on the applicability of each method is presented and previous applications are detailed. Then the more likely reservoir temperature of each well versus elevation is plotted based on the estimations about the main feed zone and the temperature of each well. The boiling with depth curve for pure water is also included. Two longitudinal and one traverse geological sections are presented to illustrate the field initial temperature distribution, the lithology and layers thickness, the basement topography and the wells traversed along each sections. Also, the main feed zones of the wells are indicated. Finally, the last series of measured temperature logs in well H-26 are produced by numerical simulation. This considers the well circulation losses and an assumed initial temperature profile. This profile iteratively modified until the computed profiles match the measured temperature profiles. The last assumed temperature profile is then considered as the best approximation to the undisturbed formation temperature around well H-26 and it is then compared with the stabilized temperatures obtained via the Horner and Sphere methods. [Spanish] Se presentan las temperaturas iniciales o estabilizadas de la formacion circundante a 40 pozos del campo geotermico Los Humeros, las cuales se estimaron mediante los metodos de Horner y el metodo de la esfera. Se presenta una discusion sobre la aplicacion de cada metodo y se detallan las aplicaciones previas del metodo de la esfera. Posteriormente y con base en las estimaciones de las principales zonas de aporte de cada pozo y sus correspondientes temperaturas se grafican las temperaturas mas probables de yacimiento para cada pozo contra la elevacion y se incluye en la misma grafica la curva de ebullicion del agua contra la elevacion. Se

Grapar vs No grapar en laringectomía total.

Directory of Open Access Journals (Sweden)

Pablo Crespo Escudero

2018-05-01

Full Text Available INTRODUCCION:- La laringectomía total data de una historia de casi 150 años (1873, realizada por BillrothLos principios del cierre faríngeo, dentro de la laringectomía total, son: conservación y eversión de la mucosa hacia la luz digestiva, hemostasia y que los tejidos no mantengan una tensión excesiva.Los rusos en 1950, son pioneros en el cierre faríngeo con suturas mecánicas, en todo dipo de cirugías.El porcentaje de fístula faringocutánea varía entre el 4-70 %, siendo la complicación más frecuente de esta cirugía.- Serie de casos ENDOLARINGEOS CON MODERLO TA-60  (1415 laringectomías del Rusian Oncological Center: % de fístula con grapadora: 11,9 %- Esta técnica SOLO se debe UTILIZAR para tumores EXCLUSIVAMENTE  ENDOLARÍNGEOS. MATERIAL Y METODOS:-        Caso número 1: paciente de años de 58 edad con tumoración glotosubglótica (carcinoma epidermoide T3 N2b Mx, que tras rechazar opción de preservación de órgano, opta por una laringectomía total + vaciamientos funcionales bilaterales;-        Caso número 2: paciente de 67 años, con tumoración glotosublglótica (carcinoma epidermoide T2N1Mx , que presenta persistencia de enfermedad tras tratamiento con QT-RT concomitant; se opta por cirugia de rescate con laringectomía total + doble vaciamiento cervical funcional bilateral.-        Se realiza consulta con nutrición y anestesia para PREPARACIÓN MULTIMODAL prequirúrgica.-        se da un punto de seda con videolaringoscopio para poder traccionar la epiglotis en el sentido traqueal en el momento de la introducción de la grapadora; Se esqueletiza la laringe, se introduce pinza en espacio interaritenoideo para coger el punto y se coloca la grapadora minuciosamente desde espacio retroaritenoideo hasta el espacio preepiglótico.-        Se utiliza la grapadora MODELO ENDO GIA (VER FOTO , teniendo que realizar el cierre en 3 disparos o cargas.-        Se comprueba el cierre

Journal of Rehabilitation Research and Development Progress Reports 1994, Volume 32, June 1995

Science.gov (United States)

1995-06-01

May 1993. La misura degli intervalli di attivazione muscolare durante il movimento: un metodo di detezione statistica, Bonato P, D’alessio T...Philadelphia, PA 19107; Division of Medical Sciences. Alfred I. dti Pont Institute, Wilmington, DP. 19803; Olsen Biochemistry Laboratories, South Dakota

Soft Tissue Masses in the Extremities: The Accuracy of an Ultrasonographic Diagnosis

Energy Technology Data Exchange (ETDEWEB)

An, Ji Young; Park, So Young; Park, Ji Seon; Jin, Wook; Ryu, Kyung Nam [Kyung Hee University Medical Center, Seoul (Korea, Republic of)

2011-09-15

We wanted to retrospectively determine the accuracy of an ultrasonographic diagnosis of superficial soft tissue masses in the extremities by using the histologic results as the reference standard. From January 2005 to June 2010, 154 patients with soft tissue masses in the extremities and who underwent ultrasonographic evaluation followed by biopsy or resection were retrospectively evaluated. The ultrasonographic and histologic diagnoses of the soft tissue masses were lipoma, ganglion cyst, hemangioma, neurogenic tumor, giant cell tumor of the tendon sheath, epidermoid cyst, fibroma, glomus tumor, Baker's cyst and neurofibromatosis. Out of 154 patients, 114 (74%) patients showed concordance between the histologic diagnosis and the ultrasonographic diagnosis, and the remaining 40 (26%) patients did not. The diagnostic accuracy of each soft tissue mass was 95% for lipoma, 83% for ganglion cyst, 75% for hemangioma, 72% for neurogenic tumor, 50% for giant cell tumor of the tendon sheath, 43% for epidermoid cyst, 33% for fibroma and 100% each for glomus tumor, fibromatosis and Baker's cyst. Aside from these tumors, there were also sarcoma, malignant melanoma, elastofibroma, Kimura disease and pilomatricoma. Among the cases that showed discordance between the histologic diagnosis and the ultrasonographic diagnosis, three of them were notable; pilomatricoma being misdiagnosed as dermatofibroma protuberans, angiolipoma being misdiagnosed as vascular leiomyoma and malignant fibrous histiocytoma being misdiagnosed as a malignant soft tissue mass. The accuracy of an ultrasonographic diagnosis for soft tissue masses in the extremities varies greatly according to each type of mass. Lipoma, ganglion cyst, hemangioma, glomus tumor, neurogenic tumor and Baker's cyst showed a relatively high rate of concordance between the ultrasonographic diagnosis and the histologic diagnosis, but epidermoid cyst and fibroma showed a relatively lower rate of concordance

MR diffusion-weighted imaging in differential diagnosis of intracranial cystic lesions

International Nuclear Information System (INIS)

Ji Xueman; Lu Guangming; Wang Zhongqiu; Zhang Zongjun; Zhang Zhiqiang; Wang Junpeng

2007-01-01

Objective: To evaluate the value of diffusion-weighted imaging (DWI) on differential diagnosis of intracranial cystic lesions. Methods: Seventy-six patients with surgically and pathologically confirmed intracranial cystic lesions undergone conventional MRI, DWI and contrast enhanced MRI examination. The signal characteristics of intracranial cystic lesions on DWI were analysed retrospectively, the apparent diffusion coefficient (ADC) values of cystic areas were measured quantitatively. Results: Nineteen brain abscesses showed hyperintense signal on DWI. Among 34 brain tumors, 3 brain gliomas were hyperintense signal, 1 brain glioma was isointense signal and 1 metastasis was hyperintense signal; the other 29 brain tumors showed hypointense signal on DWI. The ADC values of all lesions were: (0.62 ± 0.15) x 10 -3 mm 2 /s in brain abscesses, (2.39 ± 0.78) x 10 -3 mm 2 /s in brain gliomas, (2.68 ± 0.40) x 10 -3 mm 2 /s in brain hemangioblastomas, (2.79 ± 0.79) x 10 -3 mm 2 /s in brain metastases, respectively. There were significant differences between the ADC values of brain abscess and the cystic or necrotic portions of brain glioma, hemangioblastoma, metastasis (P 0.05). Seven intracranial arachnoid cysts showed hypointense signal and 16 epidermoid cysts strikingly hyperintense signal on DWI. The ADC values of arachnoid cysts and epidermoid cysts were (2.96 ± 0.36) x 10 -3 mm 2 /s and (0.94 ± 0.13) x 10 -3 mm 2 /s respectively. There was significant difference between the ADC values of arachnoid cysts and epidermoid cysts (P<0.01). Conclusion: DWI and ADC values have important contribution to the differentiation of brain abscesses from cystic or necrotic tumors, intracranial cystic lesions showing hypointense signal on DWI can exclude brain abscess. (authors)

sommaire N°13

African Journals Online (AJOL)

7 déc. 2011 ... Dysphonia is considered as its main symptom and it can be associated with dyspnea according to tumor location. It is essentially an epidermoid carcinoma. Alcohol- smoking plays an important role in the genesis of this type of cancer. Materials and methods : Our study is retrospective concerning 90 cases ...

Radiosensitivity of drug-resistant human tumour xenografts

International Nuclear Information System (INIS)

Mattern, J.; Bak, M. Jr.; Volm, M.; Hoever, K.H.

1989-01-01

The radiosensitivity of three drug-resistant sublines of a human epidermoid lung carcinoma growing as xenografts in nude mice was investigated. Drug resistance to vincristine, actinomycin D and cisplatin was developed in vivo by repeated drug treatment. It was found that all three drug-resistant tumour lines were not cross-resistant to irradiation. (orig.) [de

Valoracion economica ambiental de la calidad del aire por emisiones industriales en la ciudad de quevedo,ecuador

OpenAIRE

Espol; Cabrera Casillas, Elvis Antonio; Lozano Mendoza, Pedro Harrys

2017-01-01

El objetivo principal del estudio es realizar una valoracion economico ambiental por la mejora de la calidad del aire en quevedo, para esto se elaboro un escenario hipotètico utilizando el metodo de valoracion contingente en su formato dicotomico doble. Guayaquil CAMBIO CLIMATICO

Use and Analysis of Finite Element Methods for Problems of Solid Mechanics and Fracture

Science.gov (United States)

1993-01-19

improve global accuracy and convergence rates, specific activities such as mesh refinement may be undertaken local to the crack tips. A criticism ...Sciences, Centro Internacional de Metodos Numnericos en Ingenieria, Barcelona, 1992 11 1 |l!avacek, J Rosenberg, A E Beagles and J R Whiteman

Carcinoma vulvar

Directory of Open Access Journals (Sweden)

Yamit Peñas Zayas

2015-11-01

Full Text Available El carcinoma de la vulva tiene una incidencia de aproximadamente un 3-5% dentro de todas las enfermedades ginecológicas malignas. El 90% de los tumores malignos de la vulva está constituido por carcinoma epidermoide, el resto son adenocarcinomas, carcinomas de células basales y melanomas. Se realiza la presentación de un caso de una paciente femenina de 25 años de edad con antecedentes  de Diabetes Mellitus tipo II y trombopatia, que ingresa en el servicio de ginecología con un cuadro cutáneo polimorfo, localizado en labios mayores y menores, dado por lesiones eritematoerosivas y vegetante, sospechándose clínicamente el diagnóstico  de un carcinoma epidermoide, corroborándose el mismo histológicamente al realizarse biopsia de piel. Se indicó tratamiento con quimioterapia. Por la edad de la paciente y ser menos frecuente en mucosa que en la piel,  motivo la presentación del caso.

Ultra-high-speed oscillographic techniques; Techniques d'oscillographie ultra-rapide; Metody sverkhskorostnoj ostsillografii; Metodos oscilograficos ultrarrapidos

Energy Technology Data Exchange (ETDEWEB)

Abercrombie, S; Elphick, B; Foster, H [Atomic Weapons Research Establishment, Aldermaston (United Kingdom)

1962-04-15

100 {Omega}; e) Des resistances de complement a large bande, destinees a l'extraction des signaux de declenchement de la base de temps; / ) Des bases de temps fournissant des signaux de l'ordre de quelques nanosecondes et comportant des dispositifs de declenchement et de suppression du faisceau; g) Un appareil de prise de vues a grande ouverture. En conclusion, le memoire examine certaines applications de l'electronique nucleaire. (author) [Spanish] Despues de un resumen historico de los metodos de utilizacion de oscilografos para senales transitorias de alta velocidad, los autores examinan sus limites de aplicacion practica. En la memoria se pasa revista a los tubos de rayos catodicos apropiados para estos oscilografos, tomando en cuenta especialmente los tipos de deflexion por onda progresiva. En la memoria se estudian los siguientes componentes de un oscilografo completo para senales transitorias: a) Un tubo de rayos catodicos con deflexion por onda progresiva con conexion coaxial balanceada y una anchura de banda de 2 GHz; b) Un transformador inversor de fase con una impedancia caracteristica de 100 y 50 {Omega} y una anchura de banda de 1,5 kHz a 1,5 GHz; c) Resistencias de terminacion coaxial para frecuencias del orden de los GHz; d) Condensadores de acoplamiento compensados para usarlos en lineas coaxiales con frecuencias comprendidas entre 5 kHz y 3 GHz y 100 {Omega} de impedancia caracteristica; e) Atenuadores resistivos de banda ancha, para la extraccion de senales de disparo de base de tiempos; f) Bases de tiempo del orden de los nanosegundos, con dispositivos disparadores y supresores ; g) Una camara de gran apertura. Finalmente, los autores examinan las aplicaciones de estos oscilografos en la electronica nuclear. (author) [Russian] Posle kratkogo opisaniya ostsillograficheskogo metoda izucheniya sverkhskorostnykh perekhodnykh izluchenij obsuzhdayutsya prakticheskie vozmozhnosti ehtogo apparata. Daetsya obzor podkhodyashchikh katodnykh ehlektronnykh lamp

Ultraviolet-A1 irradiation therapy for systemic lupus erythematosus.

Science.gov (United States)

McGrath, H

2017-10-01

Systemic lupus erythematosus (lupus, SLE) is a chronic autoimmune disease characterized by the production of autoantibodies, which bind to antigens and are deposited within tissues to fix complement, resulting in widespread systemic inflammation. The studies presented herein are consistent with hyperpolarized, adenosine triphosphate (ATP)-deficient mitochondria being central to the disease process. These hyperpolarized mitochondria resist the depolarization required for activation-induced apoptosis. The mitochondrial ATP deficits add to this resistance to apoptosis and also reduce the macrophage energy that is needed to clear apoptotic bodies. In both cases, necrosis, the alternative pathway of cell death, results. Intracellular constituents spill into the blood and tissues, eliciting inflammatory responses directed at their removal. What results is "autoimmunity." Ultraviolet (UV)-A1 photons have the capacity to remediate this aberrancy. Exogenous exposure to low-dose, full-body, UV-A1 radiation generates singlet oxygen. Singlet oxygen has two major palliative actions in patients with lupus and the UV-A1 photons themselves have several more. Singlet oxygen depolarizes the hyperpolarized mitochondrion, triggering non-ATP-dependent apoptosis that deters necrosis. Next, singlet oxygen activates the gene encoding heme oxygenase (HO-1), a major governor of systemic homeostasis. HO-1 catalyzes the degradation of the oxidant heme into biliverdin (converted to bilirubin), Fe, and carbon monoxide (CO), the first three of these exerting powerful antioxidant effects, and in conjunction with a fourth, CO, protecting against injury to the coronary arteries, the central nervous system, and the lungs. The UV-A1 photons themselves directly attenuate disease in lupus by reducing B cell activity, preventing the suppression of cell-mediated immunity, slowing an epigenetic progression toward SLE, and ameliorating discoid and subacute cutaneous lupus. Finally, a combination of these mechanisms reduces levels of anticardiolipin antibodies and protects during lupus pregnancy. Capping all of this is that UV-A1 irradiation is an essentially innocuous, highly manageable, and comfortable therapeutic agency.

Ultraviolet-A1 irradiation therapy for systemic lupus erythematosus

Science.gov (United States)

2017-01-01

Systemic lupus erythematosus (lupus, SLE) is a chronic autoimmune disease characterized by the production of autoantibodies, which bind to antigens and are deposited within tissues to fix complement, resulting in widespread systemic inflammation. The studies presented herein are consistent with hyperpolarized, adenosine triphosphate (ATP)-deficient mitochondria being central to the disease process. These hyperpolarized mitochondria resist the depolarization required for activation-induced apoptosis. The mitochondrial ATP deficits add to this resistance to apoptosis and also reduce the macrophage energy that is needed to clear apoptotic bodies. In both cases, necrosis, the alternative pathway of cell death, results. Intracellular constituents spill into the blood and tissues, eliciting inflammatory responses directed at their removal. What results is “autoimmunity.” Ultraviolet (UV)-A1 photons have the capacity to remediate this aberrancy. Exogenous exposure to low-dose, full-body, UV-A1 radiation generates singlet oxygen. Singlet oxygen has two major palliative actions in patients with lupus and the UV-A1 photons themselves have several more. Singlet oxygen depolarizes the hyperpolarized mitochondrion, triggering non-ATP-dependent apoptosis that deters necrosis. Next, singlet oxygen activates the gene encoding heme oxygenase (HO-1), a major governor of systemic homeostasis. HO-1 catalyzes the degradation of the oxidant heme into biliverdin (converted to bilirubin), Fe, and carbon monoxide (CO), the first three of these exerting powerful antioxidant effects, and in conjunction with a fourth, CO, protecting against injury to the coronary arteries, the central nervous system, and the lungs. The UV-A1 photons themselves directly attenuate disease in lupus by reducing B cell activity, preventing the suppression of cell-mediated immunity, slowing an epigenetic progression toward SLE, and ameliorating discoid and subacute cutaneous lupus. Finally, a combination of these mechanisms reduces levels of anticardiolipin antibodies and protects during lupus pregnancy. Capping all of this is that UV-A1 irradiation is an essentially innocuous, highly manageable, and comfortable therapeutic agency. PMID:28480786

Protección solar en el paciente pediátrico

Directory of Open Access Journals (Sweden)

Marimar Saéz-de Ocariz

2015-08-01

Full Text Available Se denomina fotoprotección al conjunto de medidas que se pueden instaurar con el fin de proteger a la piel de la agresión producida por la exposición a los rayos solares. Incluye medidas físicas de evitación y el uso de fotoprotectores con el objetivo de prevenir posibles daños de la radiación ultravioleta en la piel.1

Sizing an isolated wind-solar-fuel cell generation system based on the particle swarm optimization method; Dimensionamiento de un sistema de generacion aislado eolico-solar-celda de combustible basado en el metodo de optimizacion de enjambre de particulas

Energy Technology Data Exchange (ETDEWEB)

Sanchez-Huerta, V; Ramirez-Arredondo, Juan M. [Universidad de Quintana Roo, Chetumal, Quintana Roo (Mexico)]. E-mail: vsanchez@gdl.cinvestav.mx; Arriaga-Hurtado, L. G. [CIDETEQ, Queretaro (Mexico)

2009-09-15

Sizing an electric energy system requires an analysis of investment, maintenance and operating costs. In the case of a generation system that uses renewable sources, optimal capacity becomes more complex compared to a conventional system, because of the randomness of renewable resources (wind, solar) and the still high costs of wind and photovoltage generator modules. This work presents the optimal sizing of a wind-solar-fuel cell generation system, minimizing the costs of the system while satisfying the energy demands of an isolated charge. The optimization method used is based on an evolutionary programming technique known as particle swarms (PSO-particle swarm optimization). The generation of energy with a hybrid system is discussed, based on the profile of insolation and wind availability at the site, with the objective of satisfying a specific electric demand. [Spanish] El dimensionamiento de un sistema de generacion de energia electrica requiere un analisis de los costos de inversion, mantenimiento y operacion. En el caso de un sistema de generacion que utiliza fuentes renovables la capacidad optima resulta mas compleja con respecto a un sistema convencional, debido a la aleatoriedad de los recursos renovables (eolico, solar), y a los aun altos costos de generadores eolicos y modulos fotovoltaicos. En este trabajo se presenta el dimensionamiento optimo de un sistema de generacion eolico-solar-celda de combustible minimizando los costos del sistema que satisfaga la energia demandada por una carga aislada. El metodo de optimizacion utilizado esta basado en una tecnica de programacion evolutiva conocida como enjambre de particulas (PSO por sus siglas en ingles: particle swarm optimization). Se plantea la generacion de energia del sistema hibrido con base a la insolacion y el perfil del viento disponible en sitio, con objeto de satisfacer una demanda electrica determinada.

The Application of Various Nondestructive Testing Methods to Fuel Elements of the Orgel Type; Application des Differentes Methodes d'Essais Non Destructifs aux Elements Combustibles du Type Orgel; Primenenie razlichnykh nedestruktivnykh metodov ispytanij k toplivnym ehlementam tipa ''orgel''; Aplicacion de Distintos Metodos de Ensayo No Destructivo a los Elementos Combustibles de Tipo Orgel

Energy Technology Data Exchange (ETDEWEB)

Bonnet, P.; Jansen, J. [EURATOM, C.C.R., Ispra (Italy)

1965-09-15

methode a un capteur montre quelles sont les limites d'utilisation de ces deux methodes. Defauts transversaux; La methode a un capteur appliquee a cette recherche fait l'objet d'une breve description. Entrainement mecanique: Le memoire fait etat d'un banc mecanique, type laboratoire, pour la recherche des criteres d'essais et d'un banc de passage des tubes, de type semi-industriel, pour l'examen en continu avec enregistrement des defauts. Les difficultes rencontrees et les moyens misenceuvrepoury remediersont evoques. c) Tests par radiographie. Cette methode fera l'objet d'un memoire special; seuls sont indiques les resultats obtenus sur tubes de force ou sur tubes de gaines. d) Test divers Les test finaux sur elements combustibles complets peuvent se resumer en deux parties. Tests d'etancheite au moyen du test a l'helium developpe par la SOGEV. Un dispositif permet d'examiner simultanement 4 ou 6 elements combustibles ou separement 2 ou 3. Tests classiques de radiographie; l'accent est mis plus particulierement sur l'etude des soudures; on donne la marge des conditions experimentales pour obtenir une bonne definition. En conclusion, les auteurs presentent un projet de chaine de controle semi-industrielle avec les differentes possibilites de traitements et essaient de degager une certaine philosophie des tests non destructifs appliques aux elements combustibles. (author) [Spanish] La memoria presenta los distintos metodos empleados para deteccion de fallas (de tipo dimensional o estructural) en vainas de elementos combustibles. Los autores describen, asimismo, los ensayos finales con elementos combustibles completos, en particular radiografia de las soldaduras y pruebas de estanqueidad. Este tema se ha tratado ya en forma parcial. El estudio de las caracteristicas dimensionales de las vainas lisas de SAP (producto de aluminio sinterizado) ha sido objeto de trabajos bastante avanzados. La memoria examina en particular los siguientes temas: 1. Medicion de diametros internos

Un universo comprensibile interazione tra scienza e teologia

CERN Document Server

Coyne, George V

2009-01-01

Perché il nostro mondo è comprensibile? La domanda sembra così banale, che solo pochi trovano il coraggio di porsela. In questo libro esploreremo le radici profonde del mistero della razionalità. L’indagine sulla razionalità del mondo cominciò duemilacinquecento anni or sono, quando un manipolo di audaci pensatori avviarono l’impresa di cercare di capire la Natura con la sola forza della ragione, rifiutando le comode e futili spiegazioni fornite da miti e leggende. Attraverso molte avventure filosofiche e teologiche, alla fine il concetto greco di razionalità pose le basi di un modo nuovo e rivoluzionario di pensare: quello del metodo scientifico, destinato a trasformare il mondo. Quando consideriamo i frutti più recenti dell’indagine sulla razionalità del mondo – la teoria della relatività, la meccanica quantistica, l’unificazione delle leggi fisiche, la gravitazione quantistica – viene da chiedersi: quali sono i limiti del metodo scientifico? Il principio fondamentale del pensiero razi...

Spectral signature of ultraviolet solar irradiance in Zacatecas

Energy Technology Data Exchange (ETDEWEB)

Pinedo V, J. L; Mireles G, F; Rios M, C; Quirino T, L. L; Davila R, J. I [Universidad Autonoma de Zacatecas, Zacatecas, Zacatecas (Mexico)

2006-10-15

This study presents an analysis of the global ultraviolet spectral irradiance (290-400 nm) registered in Zacatecas, a city near the Tropic of Cancer, located at 2500 m above sea level, latitude of 22 degrees N and longitude of 102 degrees W. The spectra have been measured using a Bentham radiometer with a 0.5 nm step in wavelength. The measurements show relatively high levels of ultraviolet irradiance (UV), which may be characteristic of areas close to the Tropic of Cancer. Faced with an increase of the incidence of skin cancer among the population of Zacatecas, these measurements highlight that a damage prevention plan is required. [Spanish] En este trabajo se presenta un analisis de la radiacion espectral global ultravioleta (290-400 nm) registrada en Zacatecas, una ciudad vecina al tropico de cancer, situada a 2500 m sobre el nivel del mar, latitud de 22 grados N y longitud de 102 grados O. Los espectros correspondientes han sido medidos mediante un espectroradiometro Bentham con un paso de 0.5 nm de longitud de onda. Las mediciones muestran niveles de radiacion ultravioleta (UV) relativamente elevados, que pueden ser caracteristicos de las zonas vecinas al tropico de cancer. Frente al aumento de incidencia de cancer en la piel en la poblacion del estado de Zacatecas, estas mediciones ponen en relieve la necesidad de formular un plan preventivo de danos.

Medición y predicción de la radiación solar global UV-B bajo cielos claros y sin nubes

Directory of Open Access Journals (Sweden)

Jaime Wright Gilmore

2016-03-01

Full Text Available Se presentan mediciones experimentales de la radiación solar ultravioleta en el rango B del espectro solar (UV-B y la radiación ultravioleta en el rango total RUV (UV-A+UV-B en días claros y sin nubes en Heredia, Costa Rica. Se utilizó una radiómetro UV-B, que mide la radiación solar en el rango espectral 280-315 nm, y un radiómetro RUV, que mide la radiación solar en el rango espectral 280-385 nm. La dependencia entre entre UV-B y RUV también fue investigada, y se encontró un excelente grado de asociación entre ambas. Además se detalló que UV-B representa solamente un 5,4% de RUV, a pesar de que UV-B es mil veces más potente que UV-A. Los valores de UV-B medidos in situ fueron comparados con los valores predichos por un modelo atmosférico espectral, el cual utiliza como datos de entrada: la hora del día, la latitud, la altitud, el albedo superficial, la distancia Tierra-Sol, la turbiedad atmosférica y el ozono atmosférico. La comparación entre los valores medidos y predichos dio resultados satisfactorios.

Efecto de la radiación ultravioleta B en la producción de polifenoles en la microalga marina Chlorella sp. Effect of ultraviolet B radiation on the production of polyphenols in the marine microalga Chlorella sp.

Directory of Open Access Journals (Sweden)

Jaime Copia

2012-03-01

Full Text Available Las algas marinas son una fuente importante de compuestos antioxidantes (fenoles y polifenoles, generados como mecanismos de defensa frente a factores de estrés (radiación UV, temperatura, herbívora. El objetivo de este trabajo es evaluar la estrategia de adaptación al efecto de la radiación ultravioleta B (RUV-B, 280-315 nm en la microalga marina Chlorella sp. mediante la producción de polifenoles y capacidad antioxidante total. Se expusieron cultivos de Chlorella sp. fueron expuestos a radiación UV-B (470 μW cm-2 por periodo de tiempos ascendentes. Se evaluó la capacidad antioxidante total DPPH, polifenoles totales, clorofila-a y b así como la densidad celular en cultivos expuestos y no expuestos. Los resultados indicaron que la RUV-B genera una disminución de la densidad celular en los cultivos irradiados por primera vez (1ª etapa, existiendo un aumento significativo (P Marine algae are an important source of antioxidant compounds (phenols and polyphenols, generated as defense mechanisms against stress factors (UV radiation, temperature, herbivory. The aim of this study was to evaluate the strategy of adaptation to the effect of ultraviolet B radiation (UV-B, 280-315 nm in the marine microalga Chlorella sp. through, the production of polyphenols and total antioxidant capacity. Chlorella sp. cultures were exposed to UV-B radiation (470 μW cm-2 over increasing time periods. We evaluated the total antioxidant capacity DPPH, total polyphenols, chlorophyll-a and b, and cell densities in exposed and unexposed cultures. The results indicated that UV-B caused a decrease in cell density in cultures irradiated for the first time (1st stage, with a significant increment (P < 0.05, lower than the control in the 2nd and 3rd stages only through the 4th stage (day 7, corresponding to a dose of 16,920 J m-2. The production of total phenols increased significantly (P < 0.05 for the IVth extract with respect to the control, confirming that the

Proceedings of the Ship Control Systems Symposium (9th) Held in Bethesda, Maryland on 10-14 September 1990. Theme: Automation in Surface Ship Control Systems, Today’s Applications and Future Trends. Volume 4

Science.gov (United States)

1990-09-14

and can be fused separately. The RTU’s low-power consumption makes them ideally suited for battery and solar powered applications. 3.5 Redundant...dei movimenti e delle sollecitazioni di una nave in mare tempestoso per mezzo del metodo dello spettro di energia e della teoria della

The Physical Oceanography of the Alboran Sea.

Science.gov (United States)

1987-03-01

relative vorticity was imposed, be critical . The vorticity mechanism proposed by however, the flow turned to the left. He suggested that Bryden and Stommel... Metodos y resultados. Inf. Teen. del Inc., Stroudsburg, Pennsylvania. I.E.O., Madrid, Spain (in press). Cheney, R. E. and R. A. Doblar (1982). Structure

A Methodology for Selection of a Satellite Servicing Architecture. Volume 3. Appendices.

Science.gov (United States)

1985-12-01

model transfers between inclined circu- lar orbits. If OSV time of flight becomes more critical . then a choice between the other two techniques is...ABSTRACT iContinue on ,viverse if necesary and identify by block, number) Title: A METODO ~LOGY FOR SELECION~ OF A SATELLITE SERVICING ARCHITEIR VOLUME

Computer program for the calculation of stresses in rotary equipment discs; Programas de computo para el calculo de esfuerzos en discos de equipo rotatorio

Energy Technology Data Exchange (ETDEWEB)

Gutierrez Delgado, Wilson; Kubiak, Janusz; Serrano Romero, Luis Enrique [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

1991-12-31

In the preliminary design and diagnosis of rotary machines is very common to utilize simple calculation methods for the mechanical and thermal stresses, dynamic and thermodynamic analysis and flow of fluids in this machines (Gutierrez et al., 1989). The analysis with these methods provides the necessary results for the project initial stage of the machine. Later on, more complex tools are employed to refine the design of some machine components. In the Gutierrez report et al., (1989) 34 programs were developed for the preliminary design and diagnosis of rotating equipment; in this article, one of them is presented in which a method for the analysis of mechanical and thermal stresses is applied in discs of uniform or variable thickness that are normally found in turbomachines and rotary equipment. [Espanol] En el diseno preliminar y diagnostico de maquinas rotatorias es muy comun emplear metodos de calculo sencillos para el analisis de esfuerzos mecanicos y termicos, analisis dinamico y termodinamico y de flujo de fluidos en estas maquinas (Gutierrez et al., 1989). El analisis con estos metodos proporcionan los resultados necesarios para la etapa del proyecto inicial de la maquina. Posteriormente, para refinar el diseno de algunos componentes de la maquina, se aplican las herramientas mas complejas. En el informe de Gutierrez et al., (1989) se desarrollan 34 programas para el diseno preliminar y diagnostico de equipo rotatorio; en este articulo, se presenta uno de ellos, en el que se emplea un metodo para el analisis de esfuerzos mecanicos y termicos en discos de espesor constante o variable que se encuentran comunmente en turbomaquinas y en equipos rotatorios.

Computer program for the calculation of stresses in rotary equipment discs; Programas de computo para el calculo de esfuerzos en discos de equipo rotatorio

Energy Technology Data Exchange (ETDEWEB)

Gutierrez Delgado, Wilson; Kubiak, Janusz; Serrano Romero, Luis Enrique [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

1990-12-31

In the preliminary design and diagnosis of rotary machines is very common to utilize simple calculation methods for the mechanical and thermal stresses, dynamic and thermodynamic analysis and flow of fluids in this machines (Gutierrez et al., 1989). The analysis with these methods provides the necessary results for the project initial stage of the machine. Later on, more complex tools are employed to refine the design of some machine components. In the Gutierrez report et al., (1989) 34 programs were developed for the preliminary design and diagnosis of rotating equipment; in this article, one of them is presented in which a method for the analysis of mechanical and thermal stresses is applied in discs of uniform or variable thickness that are normally found in turbomachines and rotary equipment. [Espanol] En el diseno preliminar y diagnostico de maquinas rotatorias es muy comun emplear metodos de calculo sencillos para el analisis de esfuerzos mecanicos y termicos, analisis dinamico y termodinamico y de flujo de fluidos en estas maquinas (Gutierrez et al., 1989). El analisis con estos metodos proporcionan los resultados necesarios para la etapa del proyecto inicial de la maquina. Posteriormente, para refinar el diseno de algunos componentes de la maquina, se aplican las herramientas mas complejas. En el informe de Gutierrez et al., (1989) se desarrollan 34 programas para el diseno preliminar y diagnostico de equipo rotatorio; en este articulo, se presenta uno de ellos, en el que se emplea un metodo para el analisis de esfuerzos mecanicos y termicos en discos de espesor constante o variable que se encuentran comunmente en turbomaquinas y en equipos rotatorios.

A microwave technique for electrical conductivity measurements in semiconductors; Un procedimiento en frecuencia de microondas para la medicion de la conductividad electrica en semiconductores

Energy Technology Data Exchange (ETDEWEB)

Ramirez, A; Zehe, A [Benemerita Universidad Autonoma de Puebla, Puebla (Mexico); Starostenko, O [Universidad de las Americas, Puebla, (Mexico); Perez, L [Benemerita Universidad Autonoma de Puebla, Puebla (Mexico)

2003-01-15

In the present paper a theoretical approach is given together with the description of the experimental technique for electrical conductivity measurements of semiconductors in frequency range of 10 GHz, corresponding to a wavelength of {lambda}= 3 cm. It is shown, that the sample conductivity, measured without the need of electrical contacts, Is practically identical with results obtained by direct current methods. The potential use of the method for dielectric measurements in samples of general shape is included in the discussion. Given that the local electrical field is known only in bodies of ellipsoidal shape, one has to apply approximation methods for sample shapes of practical relevance (cylinders, cubes, disks). Finally, the measuring range and corresponding errors are explained on the base of measurements realized with silicon samples. [Spanish] En el presente trabajo se desarrolla la teoria junto con la descripcion del arreglo experimental para la medicion de la conductividad electrica en muestras semiconductoras, utilizando un campo de microondas de {lambda}= 3 cm, correspondiente a una frecuencia n de 10 GHz. Se demuestra que la conductividad electrica medida sin la necesidad de contactos electricos es practicamente identica con resultados obtenidos por el metodo comun utilizando corriente directa (d.c.). Se incorpora en la discusion ademas el potencial del metodo para el estudio de propiedades dielectricas en muestras de geometria general. Dado que solamente en cuerpos con geometria elipsoidal se conoce bien el campo electrico local, y con esto el momento bipolar inducido, para muestras de geometrias mas practicas (cilindros, cubos, discos) se acude a metodos de aproximacion. Finalmente, se discute el rango de mediciones y errores, y se presentan mediciones concretas, utilizando muestras de silicio.

An educational method for evaluating the resistance to the treatment in the diagnosis of dyscalculia

Directory of Open Access Journals (Sweden)

Giampaolo Chiappini

2016-04-01

Full Text Available In this paper a didactical method that has been proven effective for evaluating the “resistance to the treatment” of the student is presented. This parameter is essential for distinguishing the learning difficulties in mathematics from the learning disorder of dyscalculia. The method is based on GimmeFive, an application that has been designed to develop skills in mental calculation of multi-digit additions and subtractions. In this paper we present the results of two experiments conducted with groups of students respectively with learning difficulties in mathematics and dyscalculia. These experiments allowed to show the effectiveness of the didactical method in the evaluation of the resistance to the treatment and to discuss the features that make it adequate for the evaluation of the learning disorder. An educational method for evaluating the resistance to the treatment in the diagnosis of dyscalculiaIn questo lavoro viene presentato un metodo didattico che si è dimostrato efficace per valutare la resistenza al trattamento dello studente che è uno dei parametri fondamentali per distinguere la difficoltà di apprendimento in matematica dal disturbo di apprendimento noto come discalculia. Il metodo si basa sull’uso dell’applicazione GimmeFive che è stata progettata per sviluppare competenze nel calcolo mentale di addizioni e sottrazioni a più cifre. In questo lavoro vengono presentati risultati di due sperimentazioni condotte con gruppi di studenti rispettivamente con difficoltà di apprendimento e con diagnosi di discalculia. Queste sperimentazioni hanno consentito di mostrare l’efficacia del metodo didattico nella valutazione della resistenza al trattamento e di discutere le caratteristiche che lo rendono adeguato per la valutazione del disturbo di apprendimento.

Atividades melanogênica, genotóxica e antiproliferativa de extratos de Brosimum gaudichaudii Trécul e Dorstenia brasiliensis Lam induzidas por radiação UVA.

OpenAIRE

Quevedo, Adriana Elias Pires

2011-01-01

As furanocumarinas lineares ou psoralenos são fotossensibilizadores empregados na dermatologia associados a ultravioleta A no tratamento de doenças como o vitiligo. A fotoquimioterapia tem reações adversas imediatas (náuseas, prurido, eritema e xerodermia) e tardias (carcinogênese e, possivelmente, catarata). No Brasil, não existe medicamento fitoterápico ou medicamentos contendo extratos de plantas para tratamento do vitiligo que estejam de acordo com a legislação vigente da Agência Nacional...

Ultra B2 - Promoção de ligações covalentes do colágeno corneal (Corneal cross-linking) no tratamento de ceratocone: resultados preliminares

OpenAIRE

Jankov, Mirko R; Hafezi, Farhad; Beko, Maja; Ignjatovic, Zora; Djurovic, Branislav; Markovic, Vujica; Schor, Paulo

2008-01-01

OBJETIVO: Apresentar os resultados visuais e ceratométricos, seis meses após tratamento foto-terapêutico com luz ultravioleta (UV) e vitamina B2 (Ultra B2), em pacientes com ceratocone progressivo. MÉTODOS: Vinte e cinco olhos de 20 pacientes (15 homens e 5 mulheres) com ceratocone progressivo, determinado pelo aumento de curvatura em exames seriados de topografia corneal, nos últimos seis meses foram avaliados. Acuidade visual não corrigida (UVA), acuidade visual melhor corrigida com óculos ...

Obtención y Caracterización de Revestimientos Protectores a Base de Silanos para la Protección de Aceros Galvanizados Obtention and Characterization of Silane based Films for the Protection of Galvanized Steel

OpenAIRE

Sandra R Kunst; José F Matos; Matias A Korb; Célia F Malfatti

2011-01-01

Se presenta un estudio del comportamiento de películas de silanos Gamma-Aminopropyl tirethoxysilano y del N-(Beta-Aminoethyl)-Gamma-Aminopropyl trimethoxysilano aplicados por el proceso de revestimiento por inmersión (dip-coating) sobre el acero galvanizado. Se usan los mecanismos de curado térmico y curado por irradiación ultravioleta. Los substratos y revestimientos a base de zinc reciben normalmente un tratamiento de superficie para mejorar la resistencia a la corrosión, pero usan cromo he...

Supratentorial neurenteric cyst: Analysis of 45 cases in the literature

Directory of Open Access Journals (Sweden)

Pedro Góes, M.D.

2018-03-01

Conclusions: S-NC are rare and challenging lesions. The radiological features are nonspecific, and it is difficult to differentiate enterogenous cysts from other cystic lesions such as arachnoid cyst, epidermoid or glioependymal cyst. In cases with mass effect and refractory symptoms, surgical removal is indicated, including liquid drainage, capsule removal and cisternal communication. Resection of these lesions is associated with favorable outcomes.

Cis-diamminedichloride platinum II (DDP) in the treatment of penile carcinoma.

Science.gov (United States)

Sklaroff, R B; Yagoda, A

1979-11-01

Cis-diamminedichloride platinum II (DDP) was administered to eight patients with epidermoid carcinoma of the penis. Three of six adequately treated patients had an objective response: one patient achieved complete remission of 7 months duration and 2 patients had partial remissions of 8 and 2 months, respectively. DDP appears to be an active agent in the treatment of penile carcinoma.

Application of heating in dex in Los Humeros geothermal reservoir; Comportamiento de los indices de calentamiento en el yacimiento geotermico de los Humeros

Energy Technology Data Exchange (ETDEWEB)

Aragon, Alfonso; Arellano, Victor M; Izquierdo, Georgina; Garcia, Alfonso; Barragan, Rosa Maria; Verma, Mahendra P [Instituto de Investigaciones Electricas, Temixco, Morelos (Mexico); Pizano, Arturo [Comision Federal de Electricidad, Los Humeros (Mexico)

2000-12-01

Reservoir engineering uses several methodologies to evaluate reservoir information characteristics, which in one well vary with time during its production life. One of the methods widely used is the pressure analysis by stimulating the reservoir through cold water injection. For this case, the temperature is used as stimulating parameter and the resultant perturbation is analyzed for the formation intervals in order to determine reservoir permeability and thickness. This method requires a set of temperature logs taking a different stability time. The heating index is calculated from the temperature gradient with time. The index correlated with drilling parameters such as the circulation lost volume, lithology, drilling speed, et cetera. It is used identify interesting reservoir characteristics for production and injections purposes. The method is applied on wells: Br-2 from Broadlands, New Zealand; and H-11, H-31 and H-33 from Los Humeros, Mexico. The results indicate the usefulness of this method in evaluating geothermal reservoirs. [Spanish] La ingenieria de yacimientos dispone de diversas tecnicas para la evaluacion de las caracteristicas de los espesores de la formacion en un pozo, cuyo comportamiento cambia a largo de las diferentes etapas de su vida productiva. Uno de los metodos ampliamente utilizados es el comportamiento de la presion a traves de estimulos suministrados al yacimiento. Haciendo una analogia de la presion, para el caso de inyeccion de agua fria, se utiliza la temperatura como estimulo y se analizan los disturbios que esta provoca en algunas secciones de la formacion, a partir de lo cual es factible determinar intervalos permeables en el yacimiento. El metodo requiere de un par de perfiles de temperatura registrados a diferente tiempo de reposo del pozo. Con las diferencias de temperatura respecto al tiempo, se calcula el indice de calentamiento el cual se correlaciona con los parametros disponibles, contenidos durante la perforacion, como son

Use of Metallic Endosseous Implants as a Tooth Substitute

Science.gov (United States)

1975-11-25

metallic blades driven into the bone to become an anchor for prosthetic appliances. A complete critical review of the literature on dental implants was...Otto anni di practica col into metodo d’Infibulazione i:,otallica e-ndomn,,cel lare, rfrs;ultati e considerazioni, Riv. Ital. Sto::at. , January, I

Identification and estimation ot carbohydrates using radioisotopic methods; Identification et dosage des hydrates de carbone a l'aide des radioisotopes; Identifikatsiya i opredelenie karbogidratov s pomoshch'yu radioizotopnykh metodov; Identificacion u valoracion de hidratos de carbono con ayuda de radioisotopos

Energy Technology Data Exchange (ETDEWEB)

Phillips, G O; Criddle, W J [Department of Chemistry, University College, Cardiff (United Kingdom)

1962-01-15

chromatogrammes sur bandes de papier; elle n'exige qu'une modification peu couteuse du materiel de comptage traditionnel. (author) [Spanish] Dado que los metodos analiticos clasicos no permiten obtener resultados satisfactorios, los autores han perfeccionado unos metodos de dilucion isotopica para identificar y valorar los productos que se forman en pequenas cantidades al exponer hidratos de carbono en solucion acuosa a las radiaciones gamma del {sup 60}Co. Las autorradiografias de cromatogramas sobre papel, obtenidos despues de irradiar soluciones de azucares marcados con {sup 14}C, revelan una considerable degradacion molecular. Gracias a un metodo de dilucion isotopica inverso basado en la adicion de portadores conocidos, y en la obtencion de derivados cristalizados de los fragmentos, los autores han podido determinar cuantitativamente los siguientes constituyentes. El metodo descrito por los autores permite distinguir entre estereoisomeros y valorar cada lino de ellos por separado. Asimismo puede utilizarse para resolver otros problemas de orden analitico que plantea la quimica de los hidratos de carbono. Los autores describen un nuevo metodo de exploracion y registro de la radiactividad a lo largo de las tiras de papel en las que se ha desarrollado el cromatograma. Este metodo solo requiere una modificacion poco onerosa del equipo de recuento corriente. (author) [Russian] Dlya identifikatsii i otsenki nebol'shikh kolichestv obrazovavshikhsya produktov pri obluchenii karbogidratov v vodnom rastvore gamma-aktivnym kobal'tom-60 byli razrabotany metody razbavleniya izotopov. Obychnye zhe analiticheskie metody okazalis' nedostatochnymi. Po obluchenii rastvorov S14-sakhar podgotovlennye avtoradiografii posle khromatografii na bumage ukazyvayut na znachitel'noe snizhenie. Ispol'zovanie protsedury obratnogo izotopnogo rastvora, svyazannoj s dobavkoj izvestnykh nositelej i preobrazovaniem oskolkov v derivaty kristallov, byli opredeleny kolichestvennye razmery sleduyushchikh

A Comparison of Radioisotope Methods for River Flow Measurement; Comparaison de methodes radioisotopiques de mesure du debit des cours d'eau; Sravnenie radioizotopnykh metodov izmereniya rechnykh stokov; Comparacion de los metodos radioisotopicos para medir el caudal de los rios

Energy Technology Data Exchange (ETDEWEB)

Clayton, C. G.; Smith, D. B. [Wantage Research Laboratory Atomic Energy Research Establishment Wantage, Berks (United Kingdom)

1963-08-15

consequent d'aucune utilite comme indicateur dans la mesure du debit d'un cours d'eau s'il n'est pas employe avec un entraineur; mais avec un entraineur, on observe une amelioration marquee de l'exactitude des resultats. {sup 24}Na et {sup 82}Br n'ont accuse aucune adsorption a des distances bien superieures a celles qui sont necessaires pour assurer une brassage lateral; dans la riviere la plus lente, toutefois, on a note, a plus de 660 m du point d'injection, une certaine diminution de {sup 24}Na. Le memoire contient quelques observations sur la dispersion laterale et longitudinale qui, a une certain degre, influe sur l'application generale des methodes radioisotopiques a la mesure du debit des cours d'eau. Les auteurs parviennent a la conclusion que les trois methodes donnent des resultats satisfaisants. Ils preferent, en fin'de compte, la methode d'echantillonnage continue, car elle donne les resultats les plus exacts pour, la quantite minimum d'indicateur. (author) [Spanish] Los autores han empleado los procedimientos de dilucion, muestreo continuo y recuento total en un estudio comparativo de los metodos radioisotopicos de medicion de caudales fluviales en el arroyo Aylburton, en Gloucestershire, y en los rios Usway Burn y Alwin, en Northumberland. Se trata de tres tios de caracteristicas geologicas diferentes, cuyos caudales oscilan entre 2,5 1/s y 3 m{sup 3}/s. En todos los metodos de medicion de caudales que emplean indicadores, la distancia entre el punto en que se efectua la medicion y el punto en que se anade el indicador tiene que ser suficientemente grande para que se produzca una mezcla lateral completa. Por otra parte, no debe ser excesiva para evitar que la dipersion longitudinal supere cierto valor o que se pierda parte del indicador por adsorcion en el lecho fluvial. La dispersion depende de las caracteristicas hidraulicad de la corriente y es inherente al metodo. Por su parte, la adsorcion depende del indicador elegido y de las caracteristicas geologicas

Tumors of the posterior cranial fossa; Tumoren der hinteren Schaedelgrube

Energy Technology Data Exchange (ETDEWEB)

Papanagiotou, P.; Politi, M. [Klinikum Bremen-Mitte/Bremen-Ost, Klinik fuer Diagnostische und Interventionelle Neuroradiologie, Bremen (Germany)

2016-11-15

Various types of brain tumor can occur in the region of the posterior fossa. Brain metastases in adults are the most common malignancies at this localization. Ependymomas, medulloblastomas and pilocytic astrocytomas occur mostly in children and only rarely in adults. Other tumors that occur in the posterior fossa are meningiomas, schwannomas, hemangioblastomas, brain stem gliomas and epidermoid tumors. Due to the fact that the various tumors of the posterior fossa have different treatment approaches and prognoses, an accurate and specific diagnosis is mandatory. This review discusses the imaging aspects by computed tomography (CT) and magnetic resonance imaging (MRI) of the most frequent tumors of the posterior fossa. (orig.) [German] Im Bereich der hinteren Schaedelgrube treten verschiedene Typen von Hirntumoren auf, wobei Hirnmetastasen bei Erwachsenen die haeufigsten Malignitaeten in dieser Region darstellen. Ependymome, Medulloblastome und pilozytische Astrozytome kommen meistens bei Kindern und nur selten bei Erwachsenen vor. Weitere Tumoren der hinteren Schaedelgrube sind Meningeome, Schwannome, Haemangioblastome, Hirnstammgliome und Epidermoide. Da die verschiedenen Tumoren der hinteren Schaedelgrube unterschiedliche Behandlungsansaetze sowie Prognosen haben, ist eine genaue und spezifische Diagnose obligatorisch. Dieser Review diskutiert die bildgebenden CT- und MRT-Aspekte der haeufigsten Tumoren der hinteren Schaedelgrube. (orig.)

Toxicity Study of Silver Nanoparticles Synthesized from Suaeda monoica on Hep-2 Cell Line.

Science.gov (United States)

Satyavani, Kaliyamurthi; Gurudeeban, Selvaraj; Ramanathan, Thiruganasambandam; Balasubramanian, Thangavel

2012-01-01

Recently there has been fabulous excitement in the nano-biotechnological area for the study of nanoparticles synthesis using some natural biological system, which has led the growth advanced nanomaterials. This intention made us to assess the biologically synthesized silver nanoparticles from the leaf of Suaeda monoica (S.monoica) using 1 mM silver nitrate. The leaf extract of S.monoica incubated with 1 mM silver nitrate solution and characterized by UV- spectrometer and AFM. The effect of synthesized silver nanoparticles on Human Epidermoid Larynx Carcinoma cell line was evaluated by the MTT colorimetric technique. As a result we observed gradual change in the colour of extract from greenish to brown. The synthesized silver nanoparticles confirmed by UV at 430 nm and spherical shape identified in the range of 31 nm under AFM. The effect of silver nanoparticles on Human Epidermoid Larynx Carcinoma cell line exhibits a dose-dependent toxicity for the cell tested and the viability of Hep-2 cells decreased to 50 % (IC(50)) at the concentration of 500 nM. Further findings will be determined the exact mechanisms of this cost effective Nano-treatments.

Lo status di rifugiato religioso nelle fonti del diritto internazionale: le nuove frontiere delle libertà dello spirito

Directory of Open Access Journals (Sweden)

Daniele Ferrari

2017-11-01

Full Text Available SOMMARIO: 1. Libertà religiosa e protezione internazionale: note introduttive e di metodo - 2. La nozione di religione perseguitata - 3. I contenuti di tutela della libertà religiosa dei perseguitati - 4. Le condizioni di riconoscimento dello status di rifugiato religioso - 5. La procedura di valutazione delle domande - 6. Conclusioni.

Nuevas tecnologías aplicadas a la fototerapia y fotodiagnóstico

OpenAIRE

Aguilera-Arjona, Jose

2016-01-01

Desde el descubrimiento de la luz artificial numerosas aplicaciones se han realizado desde el campo de la iluminación artificial para la mejora de la vision en interiores o la visión durante la noche. De forma similar, otras aplicaciones de la luz en el campo de la medicina han desarrollado una larga carrera desde finales del siglo XIX, cuando Niels Finsen inventó el primer sistema de iluminación ultravioleta para la cura de diferentes enfermedades cutaneas. Desde entonces, se han desarrolla...

Estudio genético de la catarata presenil

OpenAIRE

López Valverde, Gloria

2016-01-01

[ES]La catarata es la principal causa de ceguera tratable a nivel mundial. Consiste en una pérdida progresiva de la transparencia del cristalino, por lo general asociada al proceso fisiológico del envejecimiento. Sin embargo, un porcentaje de pacientes presenta cataratas en edades tempranas. La luz solar se ha relacionado como causa de su formación. Existe un grupo de genes que se encarga de la reparación del ADN ante las agresiones externas por agentes como la luz ultravioleta. Hemos est...

SUI CODICI UNIDIREZIONALI

Directory of Open Access Journals (Sweden)

Luca Tallini

1992-04-01

Full Text Available Oltre ad una breve descrizione della problematica sui codici Unidirezionali è qui data la dimostrazione di una congettura di S. Al-Bassan e B. Bose che interviene nella teoria dei suddetti autori, sulla costruzione di codici ottimali nella classe dei codici bilanciati che si ottengono con il metodo della complementazione di Knuth.

TEMPI DI TRAGITTO DELLE ONDE P* E SPESSORE DELLO STRATO DEL GRANITO NELL'ITALIA CENTRALE

Directory of Open Access Journals (Sweden)

L. Marcelli

1951-06-01

Full Text Available Proseguendo lo studio del terremoto del Gran Sasso d'Italia del5 settembre 1950 si rilevano alcune caratteristiche sismiche dell'Italiacentrale.Si determina la profondità ipocentrale con il metodo dell'angolodi emergenza. Indi si costruisce la dromocrona delle P* e si calcolalo spessore dello strato del granito relativamente alla zona.

Validação de método de doseamento e aplicação em estudo de equivalência farmacêutica de solução injetável de metronidazol

Directory of Open Access Journals (Sweden)

FELIPE REBELLO LOURENçO

2010-06-01

Full Text Available O presente trabalho tem por objetivos validar métodos por espectrofotometria de absorção no ultravioleta e cromatografia líquida de alta eficiência para o doseamento de metronidazol em solução injetável e aplicá-los em estudo de equivalência farmacêutica entre medicamento de referência, genérico e similar. Os métodos propostos para doseamento de metronidazol em solução injetável por espectrofotometria de absorção no ultravioleta e por cromatografia líquida de alta eficiência foram validados, mostrando especificidade / seletividade, linearidade e faixa linear, limite de detecção / quantificação, exatidão e precisão adequados para o uso pretendido. Os medicamentos foram avaliados quanto aos testes de determinação de pH, volume médio, identificação por espectrofotometria de absorção no infravermelho, identificação por cromatografia líquida de alta eficiência, esterilidade, endotoxinas bacterianas e doseamento por espectrofotometria de absorção no ultravioleta e por cromatografia líquida de alta eficiência. Os três medicamentos atenderam as especificações para os testes avaliados e, portanto, podem ser considerados apresentando equivalência farmacêutica. Palavras-chave: Metronidazol. Equivalência farmacêutica. Validação. Flagyl. ABSTRACT Validation of metronidazole assay methods and application to study of pharmaceutical equivalence of injectable solutions of this drug The aim of this study was to validate analytical methods, based on UV absorption spectrophotometry and high performance liquid chromatography (HPLC, to assay metronidazole supplied in injectable solutions, and to employ these methods in a study of the pharmaceutical equivalence of the original brand name medicine (‘reference’, generic and similar (brand medicines. The methods proposed for the metronidazole assay were validated, showing adequate specificity/selectivity, linearity, linear range, detection and

Estimate of Annual Ultraviolet-A Exposures in Cars in Australia

International Nuclear Information System (INIS)

Parisi, A.V.; Kimlin, M.G.

2000-01-01

The annual solar UVA exposures in four cars were estimated by measuring the UVA irradiances in the vehicles in each of the four seasons and in the morning, noon and afternoon. For the cars with untinted windows the maximum UVA irradiances in cars do not necessarily occur at noon when the outside irradiances are at their highest. Additionally, they do not occur in summer. The range of annual UVA exposures between 9:00 and 15:00 EST is 1918 to 6177 J.cm -2 for the cars without the after-market window tint. These correspond to 5% to 17% of the ambient UVA on a horizontal plane over the same period outside the cars. The range is for the different sites in the car. For the car with the after-market window tint, the range of the annual UVA exposures was 489 to 2969 J.cm -2 or 1% to 8% of the ambient UVA. (author)

Influencia del solvente en el espectro ultravioleta del 4-nitrobifenilo

Directory of Open Access Journals (Sweden)

Jaime de la Zerda L.

2009-05-01

Full Text Available Se estudiaron los efectos de solvente en la banda del 4-nitrobifenilo en los alcoholes metanol, etanol, I propanol, 2 propanol, 1-butanol, 2-metilpropanol, que fueron purificados cuidadosamente, determinándose luego el grado de pureza que resultó satisfactorio en casi todos los casos. Por ser el agua la impureza persistente en todos ellos, fue necesario estudiar su efecto con cierto detalle.

Métodos cromatográficos para determinar aminas biogênicas em alimentos de origem animal

Directory of Open Access Journals (Sweden)

César Aquiles Lázaro de la Torre

2013-12-01

Full Text Available Aminas biogenicas sao formadas como resultado da descarboxilacao de aminoacidos livres especificos. A analise desses metabolitos e de grande importancia na determinacao da qualidade e monitoramento de biogenicas como histamina e tiramina relacionadas com episodios de intoxicacao em humanos. A cromatografia e uma tecnica de separacao química usada para caracterizar aminas biogenicas. Variacoes da tecnica (cromatografia liquida, em camada delgada e gasosa tem sido amplamente usadas, porem a complexidade da matriz alimentar faz com que sejam realizadas mudancas nos processos de extracao, derivatizacao e deteccao em concordancia com cada grupo de alimento. A cromatografia liquida de alta eficiencia (CLAE e o metodo mais utilizado na determinacao de aminas biogenicas em alimentos. Contudo, devido a importancia das aminas biogenicas no controle da qualidade e a seguranca do consumidor, os pesquisadores tentam desenvolver novos metodos com o intuito de uma analise mais rapida e precisa para o controle de alimentos no mercado. O objetivo da revisao e apresentar algumas tecnicas cromatograficas aplicadas no monitoramento de aminas biogenicas em produtos de origem animal.

Il gradiente implicito nella verifica a fatica di giunzioni saldate sollecitate a fatica

Directory of Open Access Journals (Sweden)

R. Tovo

2009-07-01

Full Text Available L’incremento delle potenzialità di strumenti per la progettazione assistita (come modellatori solidi e strumenti per FEA in grado di gestire modelli molto complessi permette di ipotizzare lo sviluppo di strumenti numerici specifici per la previsione della resistenza a fatica delle giunzioni saldate. Tali strumenti potrebbero essere in grado di valutare l’influenza di geometria e carichi senza la necessità di elaborazioni successive, e spesso, del progettista (come nelle tensioni di Hot Spot. Il presente lavoro propone una metodologia di calcolo adatta alla previsione della vita a fatica di giunzioni saldate complesse. Un indice di resistenza è ottenuto innanzitutto risolvendo il problema tensionale completamente in modo numerico (agli elementi finiti. La previsione della resistenza a fatica, è calcolata facendo uso di un modello analitico basato sul gradiente implicito che assume come tensione efficace la tensione equivalente non locale derivante dalla tensione principale. Dapprima verrà tarato il metodo su prove sperimentali eseguite su giunzioni saldate a croce, successivamente il metodo verrà utilizzato per la verifica a fatica di giunzioni saldate più complesse a sviluppo tridimensionale.

La riscoperta della stereoscopia per la rappresentazione dello spazio architettonico

Directory of Open Access Journals (Sweden)

Simone Garagnani

2011-06-01

Full Text Available Il progressivo sviluppo dei metodi della rappresentazione grafica nel corso della storia è stato possibile in virtù della scoperta di strumenti e tecniche appartenenti al loro tempo: questo continuo progresso delle modalità di “raccontare” l’architettura è tuttora in corso di evoluzione, costituendo il fondamento di ogni strategia informativa e di comunicazione del progetto. Il sempre più pervasivo trattamento digitale dell’informazione, sia essa grafica che testuale, ha condotto ad una progressiva riscoperta di approcci tradizionali nella descrizione dello spazio costruito, declinandoli alle nuove tecnologie informatiche per amplificarne possibilità e valenze. È il caso della stereoscopia, diffuso metodo ottocentesco adottato in fotografia per rendere spaziale la percezione dell’immagine sfruttando la visione binoculare; oggi i modelli tridimensionali e le immagini digitali catturate da apposite fotocamere rendono l’approccio stereoscopico di immediato utilizzo anche per i profani della rappresentazione, semplificando e rendendo trasparenti i concetti di geometria proiettiva alla base del metodo. Questo contributo intende indagare le funzionalità, i vantaggi e le criticità della tecnologia stereoscopica immersiva nella moderna comunicazione del progetto d’architettura.

El xeroderma pigmentoso en su fase de proliferación cutánea tumoral

Directory of Open Access Journals (Sweden)

Ernesto Melardo Taño Espinosa

2012-03-01

Full Text Available El xeroderma pigmentoso es una enfermedad dermatológica rara, autosómica recesiva, y su etiología está relacionada con el déficit congénito de una endonucleasa que impide la reparación de ADN de las células de la piel que mutan por la incidencia de los rayos ultravioletas. La enfermedad transcurre por 3 etapas clínicas evolutivas y morfológicas. Si no están totalmente protegidos de la luz solar, los enfermos sufren un envejecimiento acelerado de la piel, y desarrollan inevitablemente lesiones oculares y dérmicas que pueden conducir a múltiples lesiones cancerosas. No existe actualmente ningún tratamiento curativo. El diagnóstico precoz y la protección frente a la radiación ultravioleta son los factores imprescindibles en el tratamiento de los pacientes afectados. Se describe la evolución clínica de una niña de 10 años con xeroderma pigmentoso, la cual presenta una fase muy avanzada de la enfermedad, con importante crecimiento de carcinomas cutáneos. El objetivo de la presente publicación es presentar un caso clínico poco frecuente de xeroderma pigmentoso, y al mismo tiempo, realizar una revisión bibliográfica con el fin de orientar el diagnóstico precoz y el tratamiento oportuno en este tipo de casos.

La recidiva tumoral en la reconstrucción nasal oncológica Tumor relapse present in oncologic nasal repair

Directory of Open Access Journals (Sweden)

Julio César Gálvez Chávez

2009-09-01

Full Text Available INTRODUCCIÓN. La recidiva tumoral es una de las complicaciones más temidas de la evolución oncológica, y además de ensombrecer el pronóstico de vida, causa la pérdida de muchas reconstrucciones y agota las posibilidades quirúrgicas restauradoras. Este estudio tuvo el objetivo de determinar la frecuencia de recidivas, la repercusión sobre la reconstrucción y la evolución médica posterior de pacientes operados de tumoraciones nasales malignas. MÉTODOS. Se realizó un estudio descriptivo retrospectivo, con 20 pacientes operados de tumoraciones nasales malignas, con reconstrucción inmediata con colgajo frontal. Los pacientes procedían del Instituto Nacional de Oncología y Radiobiología (INOR, donde fueron atendidos entre el año 2002 y el 2007. RESULTADOS. Hubo recidivas en 5 pacientes (25 % de la muestra y el 80 % de estas eran un carcinoma epidermoide. Todos los pacientes con recidiva perdieron los tejidos reconstruidos y recibieron tratamiento con radioterapia. Solo se pudo reconstruir nuevamente el defecto de uno de los pacientes; dos de los restantes fallecieron y dos continuaban vivos, sin recurrencia del tumor pero sin posibilidades de reconstrucción. CONCLUSIONES. Teniendo en cuenta la frecuencia de recidivas de los carcinomas epidermoides nasales y de su repercusión, cuando no se cuenta con la técnica histográfica de Mhos, se sugiere posponer la reconstrucción nasal hasta tanto no se realice la confirmación histológica de la exéresis completa del tumor.INTRODUCTION: Tumor relapse is one of the more fearsome complications of the oncologic course and also to obscure the life prognosis, causing the loss of many reconstructions and of exhausting the repairing surgical possibilities. The aim of this study was to determine the relapse frequency, the repercussion on the repair and the subsequent medical course of patients operated on malign nasal tumors. METHODS: We made a retrospective and descriptive study in 20 patients

Uso de la radiación UV-C en el proceso de elaboración de hortalizas de IV gama

OpenAIRE

Gutiérrez, Diego; Ruiz López, Gustavo; Sgroppo, Sonia; Rodríguez, Silvia

2016-01-01

Uno de los principales factores que limita la vida útil de las hortalizas frescas es el crecimiento de microorganismos durante el almacenamiento refrigerado. Es por ello que durante la etapa de procesamiento de hortalizas de IV gama siempre se incluye una etapa de lavado y sanitización para reducir la contaminación microbiana inicial. El uso de radiación ultravioleta artificial (UV) a una longitud de onda de 190 a 280 nm (UV-C) tiene poder germicida y puede ser eficaz para la descontaminación...

Relación transmisividad UV-Ozono durante días despejados en Badajoz (España)

OpenAIRE

Antón, Manuel; Serrano, A.; Cancillo, María Luisa; García, J. A.

2004-01-01

Ponencia presentada en: XXVIII Jornadas Científicas de la AME y V Encuentro Hispano-Luso de Meteorología celebrado en Badajoz, del 11 al 13 de febrero de 2004. De todo el espectro radiativo, tiene un interés particular el estudio de la radiación ultravioleta, debido, principalmente, a los efectos perjudiciales que puede causar sobre la salud humana. En los últimos años se ha observado un notable incremento en el flujo de radiación que llega a la superficie terrestre, motivado por el de...

Avaliação da expressão gênica de colágeno em fibroblastos tratados com extratos de fungos endofíticos

OpenAIRE

Araújo, Laíza Magalhães de

2015-01-01

O processo de envelhecimento da pele é bastante complexo e pode ser classificado como envelhecimento intrínseco, determinado primordialmente por fatores genéticos, e envelhecimento extrínseco, induzido por fatores como exposição crônica à radiação ultravioleta, consumo excessivo de álcool, tabagismo e fatores nutricionais. A pele envelhecida é caracterizada por alterações morfológicas e funcionais que podem provocar o enrugamento, descamação, ressecamento, anormalidade de pigmentação e câncer...

Tiempo de detoxificación fotocatalítica de aguas contaminadas por procesos de curtiembre, utilizando dióxido de titanio

OpenAIRE

Carcelén Romero, Luis Felipe

2008-01-01

Uno de los grandes desafíos que enfrenta la ciencia en la actualidad, es buscar la manera de eliminar los contaminantes el medio ambiente de una manera eficiente y económica. En este sentido, el aprovechamiento de la radiación ultravioleta, procedente de la energía solar es una estrategia que , como muestra el presente trabajo, da buenos resultado en la detoxificación de los contaminantes provenientes de los procesos de curtiembre. El objetivo de esta investigación , fue determinar el tiemp...

Algúns conceptos básicos de radiometría e fotometría

OpenAIRE

Flores Seijas, José Ramón

2013-01-01

Licenciatura de Física Os optoelectrónicos son dispositivos de base electrónica que emiten, modulan ou detectan radiación óptica, i.e. radiación electromagnética ultravioleta, visíbel ou infravermella. A maior parte deste tipo de dispositivos están baseados en semicondutores inorgánicos, se ben é posíbel que nun futuro os semicondutores orgánicos pasen a desempeñar un papel máis importante. Nesta unidade introdúcense unha serie de conceptos relacionados coa radiación electromagn...

Absorción de la Bencidrilamina y derivados : I. Selección de la metodología analítica

OpenAIRE

Volonté, María Guillermina; Taylor, Susana A.; Lufrano, Pablo

1986-01-01

Se correlacionan los resultados obtenidos en la valoración de bencidrilamina y derivados, a través de la utilización de tres métodos analíticos que emplean la extracción líquido-líquido y la cromatografía en capa fina como etapa preparativa, a los efectos de evitar la interferencia por parte de sustancias liberadas desde las membranas gástricas. Se observa buena concordancia de los valores medidos por espectrodensitometría y por espectrofotometría ultravioleta cuando se utiliza la cromatograf...

Short communications

African Journals Online (AJOL)

1988-08-09

Aug 9, 1988 ... metodos de trabajo con el zooplancton marino, (ed.) Boltovsky, D. INIDEP Mar del Plata, Argentina. KUO. C.M., NASH, C.E. & SHEHADEH, Z.H. 1974. A ... The state of the gonads of the striped mullet (MugU cephalus) and the sharpnose mullet (Mugi/ saliens) leaving estuaries to spawn and their reaction to ...

Transmissão de Radiação Ultravioleta Através do Pelame e da Epiderme de Bovinos Transmission of Ultraviolet Radiation Through the Haircoat and the Skin of Cattle

Directory of Open Access Journals (Sweden)

Roberto Gomes da Silva

2001-12-01

Full Text Available A transmissão de radiação ultravioleta de comprimentos de onda entre 250 e 360 nm através do pelame e da epiderme de bovinos foi determinada em laboratório, usando-se amostras de couro de animais recém-abatidos. A quantidade de radiação transmitida através do pelame depende da coloração e também das características estruturais do pelame (espessura da capa; comprimento, diâmetro, número e inclinação dos pêlos, pelas quais é definido o trajeto médio de um fóton pela massa de pêlos (L. A maior transmissão é proporcionada por pelames brancos com altos valores de L, ao passo que pelames negros em geral apresentam transmissão nula ou muito baixa. Quanto menos pigmentada a epiderme, maior a transmissão de radiação através da sua superfície. A melhor proteção é proporcionada por pelames negros com baixo valor de L sobre epiderme igualmente negra, mas em vista do aquecimento causado pela absorção de radiação térmica (em vacas Holandesas a temperatura das malhas negras atinge 44,1ºC ao mesmo tempo em que a das malhas brancas é 37,7ºC, a combinação ideal para ambientes tropicais é um pelame branco com baixo valor de L sobre epiderme negra, uma combinação dificilmente encontrada em animais de raças européias. Uma alternativa seria um pelame negro com um baixo valor de L. Animais vermelhos apresentam alta transmissão de radiação UV através da epiderme e do pelame, sendo desaconselhados para ambientes tropicais. Entretanto, foi observada uma vaca Holandesa com áreas isoladas de epiderme negra coberta com pelame branco, o que pode trazer perspectivas para uma seleção para combinações mais adequadas de epiderme e pelame em bovinos de raças européias.A laboratory study was carried on the transmission of ultraviolet radiation (UV, 250 to 360 nm wavelength through the haircoat and the skin of cattle. Fresh samples of skin were measured under a solar simulator, taking account of the pigmentation of hair and

Using of thermoradiotherapy on treatment of cancerous growths of anal canal

International Nuclear Information System (INIS)

Timofeev, Yu.M.; Zikiryakhodjaev, D.Z.

1997-01-01

In this chapter of book authors investigated using of thermoradiotherapy on treatment of cancerous growths of anal canal, methods of using of thermoradiotherapy at morbid with anal cancer, methods of irradiation, the characteristic of clinical observations, using of thermoradiotherapy at treatment of epidermoid cancer of anal zone, using of thermoradiotherapy at treatment of non epithelial cancer of anal zone and using thermoradiotherapy at others types of cancerous growths

Ovarian tumors: pathogenia, clinical pattern, echographic and histopathological diagnosis

International Nuclear Information System (INIS)

Pons Porrata, Laura Maria; Garcia Gomez, Odalis; Salmon Cruzata, Acelia

2012-01-01

Two case reports of young patients, who were treated in the Otolaryngology Department from 'Dr. Joaquin Castillo Duany' Teaching Clinical Surgical Hospital in Santiago de Cuba are presented. One of the cases presented nasal obstruction, rhinorrhoea and facial pain, for 7 months; the other one presented an increase of volume in the right ocular globe. In both, the results of the biopsy confirmed the diagnosis of differentiated nasosinusal epidermoid carcinoma

Sterilization of Normal Human Plasma and Some of its Fractions by Means of Gamma Rays; Esterilizacion del plasma normal humano y algunas de sus fracciones por medio de radiaciones gamma

Energy Technology Data Exchange (ETDEWEB)

López Martínez de Alva, L.; Crespo, Y M. [Cortina Comision Nacional de Energia Nuclear (Mexico)

1967-09-15

radiaciones ultravioleta. El otro metodo es el uso de la ß-propiolactona que se ha desechado tambien рог las alteraciones que producía en la estructura de las protefnas plasmáticas. El objeto de este trabajo, que debe considerarse como una nota preliminar, es presentar los resultados obtenidos al esterilizar por medio de radiaciones gamma ({sup 60}Co, 1,3316 MeV) con dosis variables de 2, 2,5 у 3 Mrad un producto que, como el plasma que contiene proteínas muy lábiles, podría ser fácilmente alterado en su estructura por la radiacion. Tambien se sometieron a las mismas dosis: fibrogeno puro, gamma globulina pura у albúmina de origen humano; los resultados fueron muy satisfacforios, ya que quedo de manifiesto que no se pudieron demostrar alteraciones apreciables en cuanto a su estructura, solubilidad у características bioquímicas. Mediante pruebas simples de coagulacion se puso de manifiesto que algunas de las proteínas que intervienen en este mecanismo, como la protrombina, el factor Power- Stuart у el factor Hageman, prácticamente no se alteraban. Todas las muestras de plasma у de las diferentes proteínas fueron previamente liofilizadas, procurando que el contenido máximo de humedad fuera de 0,034%, con el objeto de evitar la ionizacion del contenido de agua que la tiansformaría en agua oxigenada que alteraría у oxidaría las proteínas. Los plasmas liofilizados previamente contaminados con diferentes cepas у virus demostraron wue con dosis tan bajas como 2 Mrad quedaban esteriles. Por último, se puso de manifiesto que este es un metodo sencillo у práctico, ya que la esterilizacion puede verificarse en el envase final. (author)

Il metodo storico nella critica testuale

OpenAIRE

Giangrande, Giusseppe

2008-01-01

Se ofrecen ejemplos de cómo es posible explicar por medio de un enfoque histórico pasajes controvertidos de autores griegos y latinos. Passages of Greek and Latin authors which many a critic cannot understand can often be explained by placing them in the proper historical perspective.

Bi‑lobed Perirectal Epidermoid Cyst: An Unusual Cause of ...

African Journals Online (AJOL)

of hematochezia and a bi-lobed cystic tumor on pelvic. MRI. We successfully resected the tumor via the posterior ... The only abnormal finding on clinical examination was a ... There was an absence of the uterus ... bleeding. Symptoms of dyschezia and hematochezia may also be due to cyst inflammation or infection while ...

Pulmonary epidermoid carcinoma in a patient with acromegaly: a ...

African Journals Online (AJOL)

A 56-years-old woman was referred to our unit for partially treated acromegaly. She had a high level of insulin growth factor. She did not complain of any pulmonary symptoms and was a non-smoker. Physical examination revealed clinical features of acromegaly. She had a 13 mm pituitary adenoma and was proposed for ...

Fluid-fluid level on MR image: significance in Musculoskeletal diseases

Energy Technology Data Exchange (ETDEWEB)

Chung, Hye Won; Lee, Kyung Won [Seoul Naitonal University, Seoul (Korea, Republic of). Coll. of Medicine; Song, Chi Sung [Seoul City Boramae Hospital, Seoul (Korea, Republic of); Han, Sang Wook; Kang, Heung Sik [Seoul Naitonal University, Seoul (Korea, Republic of). Coll. of Medicine

1998-01-01

To evaluate the frequency, number and signal intensity of fluid-fluid levels of musculoskeletal diseases on MR images, and to determine the usefulness of this information for the differentiation of musculoskeletal diseases. MR images revealed fluid-fluid levels in the following diseases : giant cell tumor(6), telangiectatic osteosarcoma(4), aneurysmal bone cyst(3), synovial sarcoma(3), chondroblastoma(2), soft tissue tuberculous abscess(2), hematoma(2), hemangioma (1), neurilemmoma(1), metastasis(1), malignant fibrous histiocytoma(1), bursitis(1), pyogenic abscess(1), and epidermoid inclusion cyst(1). Fourteen benign tumors and ten malignant, three abscesses, and the epidermoid inclusion cyst showed only one fluid-fluid level in a unilocular cyst. On T1-weighted images, the signal intensities of fluid varied, but on T2-weighted images, superior layers were in most cases more hyperintense than inferior layers. Because fluid-fluid layers are a nonspecific finding, it is difficult to specifically diagnose each disease according to the number of fluid-fluid levels or signal intensity of fluid. In spite of the nonspecificity of fluid-fluid levels, they were frequently seen in cases of giant cell tumor, telangiectatic osteosarcoma, aneurysmal bone cycle, and synovial sarcoma. Nontumorous diseases such abscesses and hematomas also demonstrated this finding. (author). 11 refs., 1 tab., 4 figs.

Fluid-fluid level on MR image: significance in Musculoskeletal diseases

International Nuclear Information System (INIS)

Chung, Hye Won; Lee, Kyung Won; Han, Sang Wook; Kang, Heung Sik

1998-01-01

To evaluate the frequency, number and signal intensity of fluid-fluid levels of musculoskeletal diseases on MR images, and to determine the usefulness of this information for the differentiation of musculoskeletal diseases. MR images revealed fluid-fluid levels in the following diseases : giant cell tumor(6), telangiectatic osteosarcoma(4), aneurysmal bone cyst(3), synovial sarcoma(3), chondroblastoma(2), soft tissue tuberculous abscess(2), hematoma(2), hemangioma (1), neurilemmoma(1), metastasis(1), malignant fibrous histiocytoma(1), bursitis(1), pyogenic abscess(1), and epidermoid inclusion cyst(1). Fourteen benign tumors and ten malignant, three abscesses, and the epidermoid inclusion cyst showed only one fluid-fluid level in a unilocular cyst. On T1-weighted images, the signal intensities of fluid varied, but on T2-weighted images, superior layers were in most cases more hyperintense than inferior layers. Because fluid-fluid layers are a nonspecific finding, it is difficult to specifically diagnose each disease according to the number of fluid-fluid levels or signal intensity of fluid. In spite of the nonspecificity of fluid-fluid levels, they were frequently seen in cases of giant cell tumor, telangiectatic osteosarcoma, aneurysmal bone cycle, and synovial sarcoma. Nontumorous diseases such abscesses and hematomas also demonstrated this finding. (author). 11 refs., 1 tab., 4 figs

Lung cancer incidence among A-bomb survivors in Hiroshima and Nagasaki, 1950 - 80

International Nuclear Information System (INIS)

Yamamoto, Tsutomu; Kopecky, K.J.; Fujikura, Toshio; Tokuoka, Shoji; Monzen, Tetsuo; Nishimori, Issei; Nakashima, Eiji; Kato, Hiroo.

1987-05-01

The incidence of lung cancer during 1950 - 80 in a cohort of Japanese atomic bomb survivors and controls was investigated. A total of 1,057 cases were identified; 608 of these diagnoses were based on some form of histopathologic examination, and 442 were confirmed by the present investigators. The distributions of histological types varied significantly between the sexes (p < .001), with adenocarcinoma more frequent among women and epidermoid and small cell carcinoma more frequent among men. The distributions of primary sites did not differ significantly between the sexes. The relative risk (RR) of lung cancer increased significantly with A-bomb radiation dose (p < .0001); based on tentative 1965 dose estimates as revised in 1978 (T65DR) and a linear RR model, the estimated RR at 100 rad (± SE) is 1.41 ± 0.09. Among Hiroshima survivors the women experienced radiation-related excess RR nearly twice as great as men (p = .06). RR increased with decreasing age at the time of bombing (p = .07), and after allowing for this effect, there was no significant evidence that RR varied systematically with attained age. Small cell carcinoma displayed somewhat greater sensitivity to radiation than did adenocarcinoma or epidermoid carcinoma; however the variation between the histology-specific RR functions was not statistically significant (p = .44). (author)

Non-Destructive Testing Methods Applied to Multi-Finned SAP Tubing for Nuclear-Fuel Elements; Essais Non Destructifs de Gaines a Ailettes, en Poudre d'Aluminium Frittee, pour Elements Combustibles; Nedestruktivnye metody ispytaniya rebristykh trub iz spechennogo alyuminikiog'o poroshka dlya yadernykh toplivnykh ehlementov; Metodos de Ensayo No Destructivo Aplicados a Tubos de SAP con Aletas Multiples Destinados a Elementos Combustibles

Energy Technology Data Exchange (ETDEWEB)

Lund, S. A. [Danish Central Welding Institution, Copenhagen (Denmark); Knudsen, P. [Danish Atomic Energy Commission, Research Establishment, Risoe (Denmark)

1965-09-15

Energia Atomica de Dinamarca ha emprendido el estudio de un reactor de potencia con refrigerante organico y moderador de agua pesada. Los correspondientes elementos combustibles consisten en haces de 19 barras formadas por pastillas de dioxido de uranio sinterizado, encerradas en tubos de producto de aluminio sinterizado (SAP), de 2 m de longitud, provistos de aletas helicoidales. Para obtener condiciones optimas de transmision de calor y mantener la integridad del elemento combustible durante el funcionamiento del reactor, es necesario contar con tubos de muy alta calidad. Se citan dos ejemplos que ponen de manifiesto las estrechas tolerancias dimensionales adoptadas. Para asegurar una calidad adecuada de los tubos, se establecio un control de calidad muy estricto, basado en gran medida en la aplicacion de metodos no destructivos. Se describen en esta memoria las tecnicas desarrolladas para medir el espesor de pared y los diametros, y para descubrir defectos. La compleja seccion transversal, con 24 aletas, impide aplicar metodos ultrasonicos o de comentes de Foucault para medir el espesor de la pared. Por consiguiente, se desarrollo un calibre registrador de rayos beta, cuyo funcionamiento se basa en la atenuacion sufrida por la radiacion beta proveniente de una fuente de {sup 90}Sr colocada en el interior del tubo. Para el registro continuo del espesor de la pared del tubo con seccion transversal mas simple, de 12 aletas, se utiliza un metodo ultrasonico de resonancia por inmersion. Los diametros interno y externo (entre puntos de aletas) se registran de manera continua mediante calibres neumaticos rapidos. Las fallas se detectan mediante la tecnica de eco de impulsos ultrasonicos, y examinando los tubos con corrientes de Foucault. El metodo ultrasonico permite descubrir facilmente las fisuras transversales, pero hasta ahora ha sido imposible utilizarlo para la deteccion de defectos longitudinales. Por consiguiente, ademas del ensayo ultrasonico, se aplica el examen con

Imaging of brain tumors

Energy Technology Data Exchange (ETDEWEB)

Gaensler, E H.L. [California Univ., San Francisco, CA (United States). Dept. of Radiology

1996-12-31

The contents are diagnostic approaches, general features of tumors -hydrocephalus, edema, attenuation and/or intensity value, hemorrhage, fat, contrast enhancement, intra-axial supratentorial tumors - tumors of glial origin, oligodendrogliomas, ependymomas, subependymomas, subependymal giant cell astrocytomas, choroid plexus papilloma; midline tumors - colloid cysts, craniopharyngiomas; pineal region tumors and miscellaneous tumors i.e. primary intracerebral lymphoma, primitive neuroectodermal tumors, hemangioblastomas; extraaxial tumors - meningiomas; nerve sheath tumors -schwannomas, epidermoids, dermoids, lipomas, arachnoid cysts; metastatic tumors (8 refs.).

Imaging of brain tumors

International Nuclear Information System (INIS)

Gaensler, E.H.L.

1995-01-01

The contents are diagnostic approaches, general features of tumors -hydrocephalus, edema, attenuation and/or intensity value, hemorrhage, fat, contrast enhancement, intra-axial supratentorial tumors - tumors of glial origin, oligodendrogliomas, ependymomas, subependymomas, subependymal giant cell astrocytomas, choroid plexus papilloma; midline tumors - colloid cysts, craniopharyngiomas; pineal region tumors and miscellaneous tumors i.e. primary intracerebral lymphoma, primitive neuroectodermal tumors, hemangioblastomas; extraaxial tumors - meningiomas; nerve sheath tumors -schwannomas, epidermoids, dermoids, lipomas, arachnoid cysts; metastatic tumors (8 refs.)

Clinical and imaging features of male breast disease, with pathological correlation: a pictorial essay

International Nuclear Information System (INIS)

Ng, Angeline Mei Lian; Dissanayake, Deepthi; Wylie, Elizabeth; Metcalf, Cecily

2014-01-01

The majority of male breast diseases are benign. The most common is gynaecomastia. Although it is rare, the most critical diagnosis is a malignancy. Radiologists are generally less familiar with breast disease in males compared with females. This pictorial review will highlight the ultrasonographic, mammographic and pathological features of a spectrum of benign and malignant male breast diseases. This includes gynaecomastia, fat necrosis, lipoma, epidermoid cyst, subareolar abscess, chronic inflammation, melanoma and ductal carcinoma.

Clinical and imaging features of male breast disease, with pathological correlation: a pictorial essay

Energy Technology Data Exchange (ETDEWEB)

Ng, Angeline Mei Lian; Dissanayake, Deepthi; Wylie, Elizabeth [Department of Radiology, Royal Perth Hospital, Perth, WA (Australia); Metcalf, Cecily [Department of Pathology, Royal Perth Hospital, Perth, WA (Australia)

2014-04-15

The majority of male breast diseases are benign. The most common is gynaecomastia. Although it is rare, the most critical diagnosis is a malignancy. Radiologists are generally less familiar with breast disease in males compared with females. This pictorial review will highlight the ultrasonographic, mammographic and pathological features of a spectrum of benign and malignant male breast diseases. This includes gynaecomastia, fat necrosis, lipoma, epidermoid cyst, subareolar abscess, chronic inflammation, melanoma and ductal carcinoma.

Cancer of lung in miners

International Nuclear Information System (INIS)

Kolenic, J.; Jurgova, T.; Volckova, A.; Zimacek, J.

1995-01-01

In the period of 1983-1994 was registered at Clinic of occupational diseases 87 cases of professional cancer of lung. Mostly /85/ of cases was related to miners, by whom act as risk factor alpha ionisation from radon. Average age group was 60.2 y, average time of exposition was 21.6 y. Epidermoid carcinoma was the most frequent type of tumor /46.5 %/ of cases/. Smoking plays a supportive role. (authors)

Radiotherapy for carcinomas of the anal canal Tenon hospital experience

International Nuclear Information System (INIS)

Touboul, E.; Moureau-Zabotto, L.; Lerouge, D.; Pene, F.; Deniaud-Alexandre, E.; Schlienger, M.; Laugier, A.; Tiret, E.; Parc, R.; Sezeur, A.; Houry, S.; Gallot, D.

2003-01-01

Since 1980, curative-intent radiation therapy of epidermoid carcinoma of the anal canal is the standard first line treatment. The combined concomitant chemotherapy and radiation therapy is presently established for locally advanced tumors more than 4 cm in length and/or with nodal involvement. We report the Tenon hospital experience since 1972 concerning the long term results after radiation therapy, the modifications of the radiation technique, and the evolution of treatment strategy. (author)

Methotrexate in the treatment of penile carcinoma.

Science.gov (United States)

Sklaroff, R B; Yagoda, A

1980-01-15

Eight patients with epidermoid carcinoma of the penis received methotrexate, five with high-dose methotrexate, 250--1500 mg/m2 with citrovorum rescue Q 2--4 weeks, and three with low-dose methotrexate, 0.5--3.0 mg/kg weekly. Three (38%) patients achieved a complete or partial remission which persisted for 11, 3 and 2 months, respectively. Methotrexate appears to be an active agent in the treatment of advanced penile cancer.

Body composition using deuterated water, index of insulin resistance and cortisol levels in Costa Rican school in the metropolitan area; Composicion corporal utilizando agua deuterada, indice de resistencia a la insulina y niveles de cortisol en escolares costarricenses del area metropolitana

Energy Technology Data Exchange (ETDEWEB)

Valverde Vindas, Allan Ignacio

2014-07-01

Body composition in the Costa Rican child population is evaluated and analyzed to determine the relationship with the index of insulin resistance and serum cortisol levels. 113 children in the metropolitan area were studied using deuterium isotope techniques as reference method for overweight and obesity. Morning cortisol levels were determined by immunoassay techniques (ELISA). The insulin resistance index of 113 Costa Rican boys and girls is obtained by the homeostatic method and the relationship between body composition with index of insulin resistance or levels of cortisol [Spanish] La composicion corporal en la poblacion infantil costarricense es evaluada y analizada para determinar la relacion con el indice de resistencia a la insulina y niveles de cortisol serico. 113 ninos y ninas del area metropolitana fueron estudiados utilizando tecnicas isotopicas de deuterio como metodo de referencia para sobrepeso y obesidad. Los niveles de cortisol matutino se han determinado mediante tecnicas inmunoensayo (ELISA). El indice resistencia a la insulina de 113 ninos y ninas costarricenses es obtenido mediante el metodo homeostatico asi como la relacion entre composicion corporal con indice de resistencia a la insulina o niveles de cortisol.

The situation of the wolf (Canis lupus in the area of the Regional Park of the Simbruini Mountains / La situazione del Lupo (Canis lupus nell'area del Parco Naturale Regionale dei Monti Simbruini

Directory of Open Access Journals (Sweden)

Paolo Verucci

1992-07-01

Full Text Available Abstract This work presents the results of a field research on the species Canis lupus in the Regional Park of the Simbruini Mountains. In relation to Wolf conservation, an investigation on feral and free-roving dogs was carried out. The method of snowtracking was used for Wolves and Feral dogs, the method of sighting was used for free-roving dogs. The research underlines the importance of the Simbruini Mountains for the protection of Wolf in central Apennines and the factors, at present, threatening its survival. Riassunto Nel presente lavoro vengono illustrati i risultati di una ricerca sul campo sulla specie Canis lupus nel Parco Naturale Regionale dei Monti Simbruini. In relazione agli aspetti riguardanti la conservazione del Lupo, è stata compiuta un'indagine sul fenomeno del randagismo canino. Per i lupi e i cani inselvatichiti è stato usato il metodo dello snowtracking, per le altre categorie di Cani è stato utilizzato il metodo dell'avvistamento. La ricerca ha messo in luce l'importanza dell'area dei Simbruini per la salvaguardia del Lupo nell'Appennino centrale e i fattori che, attualmente, ne minacciano la sopravvivenza.

A method for the determination of ascorbic acid using the iron(II)-pyridine-dimethylglyoxime complex

Energy Technology Data Exchange (ETDEWEB)

Arya, S. P.; Mahajan, M. [Haryana, Kurukshetra Univ. (India). Dept. of Chemistry

1998-05-01

A simple and rapid spectrophotometric method for the determination of ascorbic acid is proposed. Ascorbic acid reduces iron (III) to iron (II) which forms a red colored complex with dimethylglyoxime in the presence of pyridine. The absorbance of the resulting solution is measured at 514 nm and a linear relationship between absorbance and concentration of ascorbic acid is observed up to 14 {mu}g ml{sup -1}. Studies on the interference of substances usually associated with ascorbic acid have been carried out and the applicability of the method has been tested by analysing pharmaceutical preparations of vitamin C. [Italiano] Si propone un rapido e semplice metodo spettrofotometrico per la determinazione dell`acido ascorbico. L`acido ascorbico riduce il ferro(III) a ferro(II) che forma con la dimetilgliossima, in presenza di piridina, un complesso colorato in rosso. L`assorbanza della soluzione risultante e` misurata a 514 nm e si ottiene una relazione lineare tra assorbanza e concentrazione dell`acido ascorbico fino a 14 {mu}g ml{sup -1}. Si sono condotti studi sugli interferenti usualmente associati all`acido ascorbico ed e` stata valutata l`applicabilita` del metodo all`analisi di preparati farmaceutici di vitamina C.

Learning on the fly with the analogical method

Directory of Open Access Journals (Sweden)

Zara Mehrnoosh

2016-04-01

Full Text Available Today in Italy 20-25% of students in primary school is reported to have difficulties with mathematical skills, although several researchers have noticed a man’s natural predisposition towards numbers. In the light of this high number of reports becomes therefore necessary to reconsider the didactic context to better support the natural evolution of numerical and mathematical cognition from early childhood. The following article presents the analogical method developed by Camillo Bortolato: non-conceptual didactic path focused on semantic process, subitizing and mental math. Apprendere al volo con il metodo analogicoAd oggi in Italia il 20-25% degli alunni nella scuola primaria viene segnalato per difficoltà nel calcolo, nonostante diversi ricercatori abbiano evidenziato una naturale predisposizione dell’uomo verso la numerosità. Alla luce di questo elevato numero di segnalazioni diviene necessario ripensare il contesto didattico per sostenere al meglio e fin dalla prima infanzia la naturale evoluzione della cognizione numerica e di calcolo. Nel seguente articolo viene presentato il metodo analogico di Camillo Bortolato, un percorso didattico non concettuale attento ai processi semantici, al ruolo del subitizing e del calcolo a mente.

Embalagens plásticas e de vidro para produtos farmacêuticos: avaliação das propriedades de barreira à luz

OpenAIRE

R. M.V. Alves; S. B.M. Jaime; M. P. Gonçalves; P. W. Suzuki

2009-01-01

A estabilidade de produtos farmacêuticos fotossensíveis é afetada pela luz, que catalisa reações de degradação. O objetivo deste estudo foi avaliar a eficiência de diferentes resinas, coloração, espessura e presença de absorvedores de radiação ultravioleta (UV) como promotores de barreira à luz em embalagens plásticas e de vidro para produtos farmacêuticos. A Farmaco...

Classification of fecal contamination on leafy greens by hyperspectral imaging

Science.gov (United States)

Yang, Chun-Chieh; Jun, Won; Kim, Moon S.; Chao, Kaunglin; Kang, Sukwon; Chan, Diane E.; Lefcourt, Alan

2010-04-01

This paper reported the development of hyperspectral fluorescence imaging system using ultraviolet-A excitation (320-400 nm) for detection of bovine fecal contaminants on the abaxial and adaxial surfaces of romaine lettuce and baby spinach leaves. Six spots of fecal contamination were applied to each of 40 lettuce and 40 spinach leaves. In this study, the wavebands at 666 nm and 680 nm were selected by the correlation analysis. The two-band ratio, 666 nm / 680 nm, of fluorescence intensity was used to differentiate the contaminated spots from uncontaminated leaf area. The proposed method could accurately detect all of the contaminated spots.

Influencia de la radiación solar en la salud de las personas en la ciudad de Moquegua

OpenAIRE

Rodríguez Ordoñez, Freddi Roland

2015-01-01

La presente investigación se realizó con el objetivo de comprobar la influencia de la radiación solar en la salud de las personas; para concretar esta investigación se aplicó las técnicas: análisis de contenido, fichaje y una encuesta, teniendo en cuenta instrumentos preparados de acuerdo a los objetivos específicos de la investigación. Se solicitó datos históricos de la radiación solar ultravioleta al Servicio Nacional de Meteorología e Hidrología del Perú (SENAMHI); al Hospital Regional de ...

Síntesis hidrotérmica del Estanato de Cinc (Zn2SnO4)

OpenAIRE

Solís, José; Naupa, Alexander

2011-01-01

Se sintetizó el estanato de cinc, Zn2SnO4 (ZTO), por el método hidrotérmico empleando una temperatura de 200 °C durante 16 h. El material obtenido fue caracterizado por difracción de rayos X (DRX) y microscopia electrónica de transmisión (MET). El tamaño de grano calculado empleando el software Topas Academic fue de 30 nm. La actividad fotocatalítica del ZTO fue evaluada estudiando la degradación del colorante anaranjado de metilo en solución acuosa bajo iluminación de luz ultravioleta. Los r...

Efectos de una intervención educativa en los conocimientos y comportamientos relacionados con la fotoprotección durante la práctica de la actividad física en los estudiantes de un colegio público de Bogotá D.C., Colombia

OpenAIRE

Charry Angel, Carlos Edifrey

2016-01-01

Introducción: La incidencia del cáncer de piel melanoma y no melanoma es un problema de salud pública a nivel mundial. El incremento en la incidencia del cáncer de piel en los últimos años se debe a múltiples factores como: cambios en los estilos de vida, el envejecimiento de la población, cambios ambientales, el desconocimiento a la exposición a la radiación ultravioleta (RUV) durante la práctica de actividad física sin elementos de fotoprotección, siendo éste último reconocido como el princ...

Apoio à autoavaliação de sinais da pele na perspetiva de prevenção do cancro cutâneo

OpenAIRE

Matias, Guilhermina do Carmo Andrade Negrinho

2016-01-01

Dissertação de mestrado, Ciências Farmacêuticas, Faculdade de Ciências e Tecnologia, Universidade do Algarve, 2016 A cada ano surgem dez mil novos casos de cancro de pele em Portugal, provocados por exposições solares excessivas, segundo dados da Associação Portuguesa de Cancro Cutâneo. Portugal, por se tratar de um país com elevada taxa de incidência de sol por ano torna a população portuguesa muito suscetível aos efeitos nocivos da radiação ultravioleta. Os danos na pele provocados...

Efecto de la terapia UVB de banda estrecha sobre la síntesis de vitamina D y los parámetros de síndrome metabólico en pacientes con psoriasis moderada y grave

OpenAIRE

Romaní de Gabriel, Jorge

2013-01-01

La psoriasis es una enfermedad cutánea crónica que ha sido relacionada con el síndrome metabólico. El objetivo de este trabajo fue evaluar en pacientes con psoriasis la presencia de alteraciones en parámetros antropométricos y marcadores séricos relacionados con el síndrome metabólico, y su modificación tras un tratamiento con ultravioleta B de banda estrecha. Comparamos a 50 pacientes con psoriasis con 50 controles emparejados por sus características antropométricas (edad, sexo e índice de m...

Radiación solar y prevención del cáncer de piel

OpenAIRE

Zapater López, María

2017-01-01

Introducción. El cáncer de piel se considera un problema de Salud Pública. Se clasifica en: cáncer de piel no melanoma (que, a su vez, se divide en cáncer basocelular y cáncer espinocelular) y cáncer melanoma. El primero es más frecuente y tiene un pronóstico relativamente bueno; el segundo es menos frecuente y su pronóstico puede ser infausto. Objetivos. El objetivo principal del trabajo es profundizar en la influencia de la radiación ultravioleta en el cáncer de piel y valorar posibles f...

Carcinoma de células escamosas em bovinos, ovinos e eqüinos: estudo de 50 casos no sul do Rio Grande do Sul

OpenAIRE

Adriano Tony Ramos; Diego Mollerke Norte; Fabiana Elias; Cristina Gevehr Fernandes

2007-01-01

O carcinoma de células escamosas (CCE) é um tumor maligno dos queratinócitos. O desenvolvimento desse tipo de tumor está associado a muitos fatores, incluindo a exposição prolongada à luz ultravioleta, falta de pigmento na epiderme, perda de pêlos ou cobertura de pêlos muito esparsa nos locais afetados. Realizou-se um estudo retrospectivo dos casos de carcinoma de células escamosas em animais de produção (bovinos, ovinos e eqüinos) de 1978 a 2002. O material foi obtido nos arquivos do Laborat...

OPTIMIZACIJA IN VALIDACIJA HPLC METODE ZA UGOTAVLJANJE VSEBNOSTI ARBUTINA V PRIPRAVKIH Z EKSTRAKTOM VEDNOZELENEGA GORNIKA (ARCTOSTAPHYLOS UVA-URSI L.)

OpenAIRE

Rajh, Eva

2010-01-01

Pripravki, ki vsebujejo ekstrakt ali učinkovino vednozelenega gornika, se zaradi vsebnosti arbutina, ki ima antiseptično delovanje, pogosto uporabljajo kot uroantiseptiki za samozdravljenje. Za namene zagotavljanja ustrezne kakovosti in pravilnega odmerjanja galenskega izdelka, ki so ga razvili v Javnem zdravstvenem zavodu Mariborskih lekarn Maribor, smo optimirali in validirali HPLC metodo, ki omogoča ugotavljanje vsebnosti arbutina v pripravkih, ki vsebujejo ekstrakt vednozelenega gorni...

Techniques for contact and contact with friction problems; Tecnicas para problemas de contacto y contacto con friccion

Energy Technology Data Exchange (ETDEWEB)

Velandia Arana, Gonzalo [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

1990-12-31

Different numerical techniques are presented based in the finite element method to obtain numerical solutions to contact and contact with friction problems between solid bodies, and compared between each other. [Espanol] Se presentan diferentes tecnicas numericas basadas en el metodo de elementos finitos para la obtencion de soluciones numericas de problemas de contacto y contacto con friccion entre cuerpos solidos, y se comparan entre si.

Techniques for contact and contact with friction problems; Tecnicas para problemas de contacto y contacto con friccion

Energy Technology Data Exchange (ETDEWEB)

Velandia Arana, Gonzalo [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

1989-12-31

Different numerical techniques are presented based in the finite element method to obtain numerical solutions to contact and contact with friction problems between solid bodies, and compared between each other. [Espanol] Se presentan diferentes tecnicas numericas basadas en el metodo de elementos finitos para la obtencion de soluciones numericas de problemas de contacto y contacto con friccion entre cuerpos solidos, y se comparan entre si.

International Conference on Chemical Kinetics: Program and Abstracts Held in Gaithersburg, Maryland on 17-19 June 1985.

Science.gov (United States)

1985-06-01

Salamanca Dpto. Fisica Teorica and University Complutense Dpto. Metodos Matematicos de la F1sica The authors show how the knowledge of (n-1) first...M. Dominguez. Centro de Quimica, Instituto Venezolano de Investigaciones Cientificas Caracas 1010-A. Venezuela. The kinetics of the gas phase...Alexandra Rotinov, Rosa M. Domfnguez, and Ignacio Martin Centro de Qufmica, Instituto Venezolano de Investigaciones Cientificas (I.V.I.C.), Caracas

Reconocimiento geotécnico del terreno

OpenAIRE

Suriol Castellví, Josep; Lloret Morancho, Antonio; Josa Garcia-Tornel, Alejandro

2007-01-01

El presente texto trata de introducir al estudiante de Geotecnia a la problemática derivada del estudio del terreno como medio natural. Surge entonces la necesidad de transformar las propiedades del terreno en parámetros útiles al cálculo geotécnico. Los metodos de reconocimiento y los ensayos descritos tienen como objeto dar la solución a dicha problemática.

Definitive treatment of anal canal carcinoma with radiotherapy: Adverse impact of a pre-radiation resection. A retrospective study of 57 patients treated with curative intent

International Nuclear Information System (INIS)

Coquard, R.; Cenni, J.C.; Artru, P.; Lledo, G.; Chalabreysse, P.; Queneau, P.E.; Taieb, S.; Alessio, A.

2009-01-01

Purpose To describe retrospectively the overall survival, the cancer specific survival and the tumor control in an homogeneous series of patients with epidermoid carcinoma of the anal canal treated with definitive radiotherapy; to assess the impact of brachytherapy, chemotherapy and pre-radiotherapy resection on the risk of recurrence. Patients and methods From 1997 to 2007, 57 patients (pts) presenting with an epidermoid carcinoma of the anal canal (T1: 14, T2: 33, T3-4: 10, N0: 31, N1: 19, N2: 3, N3: 4, M0: 57) were treated with definitive radiotherapy by the same radiation oncologist. The treatment included an external beam irradiation (E.B.R.T.) given to the posterior pelvis (45 Gy/25 fractions) and, six weeks later, a boost delivered with interstitial brachytherapy (37/57) or external beam irradiation (20/57). Twelve pts had undergone a surgical resection of the tumour before radiotherapy. A belly board was used for E.B.R.T. in 13 pts. A concurrent platinum based chemotherapy was done in 42 pts. The mean follow-up was 57 months. Results The overall survival rate at 5 years was 89% with a cause specific survival of 96%. Five patients recurred (5-year rate: 12%: four had local relapse (5-year rate: 8%), four had groin recurrence, and distant metastases were seen in two. In univariate analysis, the risk of relapse was higher in patients who had undergone a pre-radiation excision (p = 0.018), in those who did not receive chemotherapy (p = 0.076) and in those who were irradiated on a belly board (p = 0.049). In multivariate analysis, a pre-radiotherapy resection (p = 0.084) had an inverse impact on the tumour control reaching the level of statistical significance and the use of a belly board was of marginal influence (p = 0.13). Conclusion Radiotherapy and chemo radiation with cisplatin-based chemotherapy cure a vast majority of patients with epidermoid carcinoma of the anal canal. Therapeutic factors that may interfere with the definition of the target volume and

Analysis of computed tomographic manifestations of primary lung cancer by histologic types

International Nuclear Information System (INIS)

Kim, Kyo Yeoun; Choe, Kyu Ok

1988-01-01

It is well known that primary lung cancer is one of the most common malignancies in Korea. With respect to the histologic type, primary lung carcinoma manifests itself in a number of different ways. The authors analyzed the computed tomographic (C-T) findings of 183 cases of pathologically confirmed primary lung cancer from 1983 to Aug. 1987 without prior information of histologic types. The results are as follows. 1. The distribution of histologic types of primary lung cancer was as follows: epidermoid carcinoma, 96 cases (52.5%); adenocarcinoma, 43 cases (23.5%); undifferentiated large cell carcinoma, 17 cases (9.2%) and undifferentiated small cell carcinoma, 27 cases (14.8%). 2. The male to female ratio was 3.9:1, the highest ratio occurring in undifferentiated small cell carcinoma 12.5:1 and the lowest ratio in adenocarcinoma 1.1:1 where there was no significant difference in the male to female ratio. 3. Chest computed tomographic findings by histologic type were as follows: (a) Epidermoid carcinoma (96 cases): The central type was the most prevalent (52 cases) with an incidence of 54%. Major air way obstruction was most frequently encountered in this type and was complete in 60% of the cases and partial in 25%. The incidence of cavitating malignancy was 10%, more common than other histologica types. (b) Adenocarcinoma (43 cases): The peripheral type was the most prevalent (28 cases) with an incidence of 63%. Lung to lung metastasis was 23%, more common than other histologic types. (c) Undifferentiated large cell carcinoma (17 cases): The highest incidence occurred in the peripheral type, 9 cases (53%). Chest wall involvement was 12%, more common than other histologic types. (d) Undifferentiated small cell carcinoma (27 cases): The central type (19 cases) presented the highest incidence (70%). Major air way obstruction was noted less severe than epidermoid carcinoma: complete 33%, partial 63%. The incidence of pericardial effusion and/or thickening was 18

Intensities of incident and transmitted ultraviolet-a rays through gafchromic films

Directory of Open Access Journals (Sweden)

Toshizo Katsuda

2017-01-01

Full Text Available Gafchromic films have been applied to X-ray dosimetry in diagnostic radiology. To correct nonuniformity errors in Gafchromic films, X-rays in the double-exposure technique can be replaced with ultraviolet (UV-A rays. Intensities of the incident and transmitted UV-A rays were measured. However, it is unclear whether the chemical color change of Gafchromic films affects the UV-A transmission intensity. Gafchromic EBT3 films were suitable to be used in this study because non-UV protection layers are present on both sides of the film. The film is placed between UV-A ray light-emitting diodes and a probe of a UV meter. Gafchromic EBT3 films were irradiated by UV-A rays for up to 60 min. Data for analysis were obtained in the subsequent 60 min. Images from before and after UV-A irradiation were subtracted. When using 375 nm UV-A, the mean ± standard deviation (SD of the pixel values in the subtracted image was remarkably high (11,194.15 ± 586.63. However, the UV-A transmissivity remained constant throughout the 60 min irradiation period. The mean ± SD UV-A transmission intensity was 184.48 ± 0.50 μm/cm2. Our findings demonstrate that color density changes in Gafchromic EBT3 films do not affect their UV-A transmission. Therefore, Gafchromic films were irradiated by UV-A rays as a preexposure.

Analysis of the innovation needs of SME; Analisi della domanda di innovazione delle PMI

Energy Technology Data Exchange (ETDEWEB)

Sabattinin, A; Finelli, A; Rappini, R; Zacchiroli, R. [ENEA, Centro Richerche `E. Clementel`, Bologna (Italy)

1998-12-31

Within an EU financial support (Innovation Relay-Centre IRENE), was set up and tested a method to identify the innovation needs of SMEs. This method, based on firm visits and audits, has proved successful as it is possible to contact firms which find it difficult to approach research centres. These firms are left on their own towards innovation and they cannot evaluate the energetic and environmental implications of introducing a new process or carrying out a new product. The results obtained have highlighted that it is possible to realise a very interesting action of technological transfer starting from the requests for innovation and by means of direct contacts and relationships between firms and research centres. When the SMEs are directly involved they become aware of energetic and environmental problems and, in general, of the engagement that Italy undertook during the conference held in Kyoto. This method is particularly useful to the research centres to which firms can point out and transfer their needs. [Italiano] Nell`ambito di un finanziamento comunitario (Innovation Relay-Centre IRENE), e` stato messo a punto e testato un metodo per l`individuazione della domanda di innovzione delle PMI. Il metodo, basato su visite aziendali e audit, si e` dimostrato particolarmente efficace perche` permette di approcciare anche aziende che hanno grandi difficolta` ad avvicinarsi al mondo della ricerca. Queste imprese sono sole nei confronti dell`innovazione e non sono in grado di valutare quali possano essere le implicazioni, anche energetiche o ambientali, consguenti all`introduzzione di un nuovo processo o alla realizzazione di un nuovo prodotto. I risultati ottenuti hanno evidenziato che, partendo dalla domanda e attraverso il contatto diretto e il dialogo con le strutture di ricerca, e`possibile realizzare interventi di trasferimento tecnologico di grande interesse. Il coinvolgimento diretto permette altresi` di sensibilizzare le PMI sulle problematiche energetiche

Influência da maceração carbônica e da irradiação ultravioleta nos níveis de trans-resveratrol em vinhos de uva cabernet sauvignon Influence of the carbonic maceration on the levels of trans-resveratrol in cabernet sauvignon wine

Directory of Open Access Journals (Sweden)

Silvana Maria Michelin Bertagnolli

2007-03-01

Full Text Available O consumo moderado de vinho reduz significativamente os riscos de doenças cardiovasculares. Este efeito é atribuído aos polifenóis presentes no vinho, em especial ao resveratrol (3,5,4'-triidroxiestilbeno, que é uma fitoalexina encontrada em várias partes da videira, principalmente na casca da uva, assim como em outras espécies de plantas. Uvas da cultivar Cabernet Sauvignon foram submetidas à irradiação com luz ultravioleta e maceração carbônica e após fermentadas. Procedeu-se à coleta de amostras durante todo o experimento, as quais foram posteriormente analisadas quanto ao teor de trans-resveratrol através da Cromatografia Líquida de Alta Eficiência. Os resultados do trabalho demonstram que a evolução do conteúdo de trans-resveratrol foi ascendente durante as fases da fermentação. Diferenças ocorreram no final da fermentação, em que as amostras de vinhos com maceração carbônica apresentaram leve declínio, possivelmente pela atmosfera de CO2 na qual ficaram armazenadas, inibindo a formação do resveratrol. Ao final da fermentação principal a concentração de trans-resveratrol foi de 15 mg.L-1 em todos os tratamentos, chegando a 1,5 mg.L-1, em média, no final do período de estocagem.The moderate consumption of wine reduces the risks of heart diseases significantly. This effect is attributed to the polyphenols found in the wine, in special to resveratrol (3,5,4'-trihidroxistilbene that it is a phytoalexin found in the various parts of the vine, including in the skin of the grape, as well as in other species of plants. Grapes of cultivar Cabernet Sauvignon had been submitted to the irradiation with ultra-violet light and carbonic maceration and after fermented. It was proceeded all collection from samples during the experiment, which later had been analyzed how much to the concentration of trans-resveratrol using the Liquid Chromatography of High Efficiency. The of the content of trans-resveratrol was ascendent

Radionuclide injury to the lung

International Nuclear Information System (INIS)

Dagle, G.E.; Sanders, C.L.

1984-01-01

Radionuclide injury to the lung has been studied in rats, hamsters, dogs, mice and baboons. Exposure of the lung to high dose levels of radionuclides produces a spectrum of progressively more severe functional and morphological changes, ranging from radiation pneumonitis and fibrosis to lung tumors. These changes are somewhat similar for different species. Their severity can be related to the absorbed radiation dose (measured in rads) produced by alpha, beta or gamma radiation emanating from various deposited radionuclides. The chemicophysical forms of radionuclides and spatial-temporal factors are also important variables. As with other forms of injury to the lung, repair attempts are highlighted by fibrosis and proliferation of pulmonary epithelium. Lung tumors are the principal late effect observed in experimental animals following pulmonary deposition of radionuclides at dose levels that do not result in early deaths from radiation pneumonitis or fibrosis. The predominant lung tumors described have been of epithelial origin and have been classified, in decreasing frequency of occurrence, as adenocarcinoma, bronchioloalveolar carcinoma, epidermoid carcinomas and combined epidermoid and adenocarcinoma. Mesothelioma and fibrosarcoma have been observed in rats, but less commonly in other species. Hemangiosarcomas were frequently observed in dogs exposed to beta-gamma emitters, and occasionally in rats exposed to alpha emitters. These morphologic changes in the lungs of experimental animals were reviewed and issues relevant to the prediction of human hazards discussed. 88 references

Spinal dermoid cyst

International Nuclear Information System (INIS)

Miyamoto, Yoshihisa; Makita, Yasumasa; Nabeshima, Sachio; Tei, Taikyoku; Keyaki, Atsushi; Takahashi, Jun; Kawamura, Junichiro

1987-01-01

A 25-year-old male complained of intermittent, sharp pains about the left eye and in the left side of the chest. Neurological examination revealed paresthesia and impaired perception of touch and pin-pricks in the dermatomes of Th8 and Th9 on the left side. In all four extremities, the muscle stretch reflexes were equal and slightly hyperactive, without weakness or sensory deficits. Metrizamide myelography showed defective filling at the level between the upper 8th and 9th thoracic vertebrae. The lesion was also demonstrated by computed tomography (CT) scan performed 1 hour later, appearing as an oval, radiolucent mass in the left dorsal spinal canal, which compressed the spinal cord forward and toward the right. Serial sections of the spinal canal revealed the lesion to be partly filled with contrast medium. Repeat CT scan 24 hours after metrizamide myelography showed more contrast medium in the periphery of the lesion, giving it a doughnut-shaped appearance. At surgery a smooth-surfaced cyst containing sebum and white hair was totally removed from the intradural extramedullary space. The histological diagnosis was dermoid cyst. There have been a few reported cases of intracranial epidermoid cyst in which filling of the cyst was suggested on metrizamide CT myelography. These findings may complicate the differential diagnosis of arachnoid cyst and dermoid or epidermoid cyst when only CT is used. (author)

Estudio sobre los tumores malignos maxilofaciales

Directory of Open Access Journals (Sweden)

Juan Carlos Quintana Díaz

1998-08-01

Full Text Available Se realizó un análisis durante el trienio 1994-1996 y se estudiaron los tumores malignos de la región maxilofacial tratados en el Servicio de Cirugía Maxilofacial de Artemisa. El sexo masculino fue más afectado que el femenino, los tumores de la piel fueron los más frecuentes, afectaron en elevado porcentaje a los pacientes de tez blanca, y el carcinoma basocelular fue el tipo histológico que más se observó. En cuanto a la localización más frecuente en la cavidad bucal fue el labio inferior, y el tipo histológico que más predominó fue el carcinoma epidermoide. El 3 % de todos los tumores encontrados correspondieron con metástasis, que debutaron por la zona bucofacial.An analytical study of the maxillofacial region malignant tumors treated in the Maxillofacial Surgery Service of Artemisa municipality was conducted from 1994-1996. Males were the most affected; skin tumors were the most frequent, a higher percentage of white people were affected and the most observed histological type was the basal cell carcinoma. The most common location in the oral cavity was the lower lip and the most predominant histological type was the epidermoid carcinoma. 3 % of all tumors found resulted in metastasis which started in the buccofacial area.

Evaluation of angiogenesis with the expression of VEGF and CD34 in human non-small cell lung cancer.

Science.gov (United States)

Inda, A M; Andrini, L B; García, M N; García, A L; Fernández Blanco, A; Furnus, C C; Galletti, S M; Prat, G D; Errecalde, A L

2007-09-01

Angiogenesis is an essential process in the progression of malignant tumors and the most potent angiogenic factor is the vascular endothelial growth factor (VEGF). On the other hand, the CD34 is an endothelial antigen that has been used to highlight the microvasculature vessel density (MVD) as a direct marker of the degree of neoangiogenesis. In the present study we report the VEGF expression and its relationship with MVD, measured by CD34, in two lineages of non-small cell lung cancer (NSCL): low differentiated adenocarcinomas and epidermoid carcinomas, in order to consider the possibility of using the correlation between both antibodies as a prognostic factor. Tumor sections were stained by immunohistochemistry for CD34 and VEGF. The results showed that the mean value of VEGF for adenocarcinoma was significantly higher than the one for epidermoid carcinoma (p < 0.001). However, the mean of MVD did not show significant differences between both types of tumors. The conventional factors taken into consideration (age over 60, sex, and presence of lymph nodes) was not significantly related to the angiogenic factors examined. In conclusion, we could affirm that CD34 is a better prognostic marker of neoangiogenesis in NSCLC, because both types of tumors have the same clinical prognosis, and so we expected the same behaviour from both markers.

Recurrent Complete Pharyngo-Oesophageal Stricture Treated by Multidisciplinary Anterograde-Retrograde Endoscopic Dilation

Directory of Open Access Journals (Sweden)

Paulo Castro Soares

2016-10-01

Full Text Available Complete pharyngo-oesophageal stricture (PES after radiotherapy for head and neck cancer is a relatively rare and difficult complication to manage. Historically this condition has been treated surgically, but endoscopic approaches are now available. We present a 61-year-old man with an epidermoid carcinoma of the supraglottic stage and a micro-invasive epidermoid carcinoma of the oropharynx treated surgically and subsequently by adjuvant radiotherapy. Eight months after the end of the radiotherapy, a complete PES was diagnosed and treated with a combined anterograde-retrograde endoscopic dilation (CARD. The procedure was performed using a transoral anterograde progression with a rigid pharyngoscope and a retrograde progression with an extra-slim nasal endoscope using the percutaneous gastrostomy already in place. Using both transillumination and direct visualisation from both sides of the complete stenosis patency was restored between the neopharynx and the oesophagus. Despite the use of an endoprosthesis, the complete PES recurred and the technique had to be performed a second time. Illustrating the complexity of the case different types of endoprosthesis and several dilations had to be performed for our patient to achieve and maintain a normal oral intake. This case report illustrates that even in complicated recurrent radiation-induced complete PES a CARD can be performed safely and successfully using different types of endoprosthesis.

Spinal dermoid cyst. Characteristic CT findings after metrizamide myelography

Energy Technology Data Exchange (ETDEWEB)

Miyamoto, Yoshihisa; Makita, Yasumasa; Nabeshima, Sachio; Tei, Taikyoku; Keyaki, Atsushi; Takahashi, Jun; Kawamura, Junichiro

1987-10-01

A 25-year-old male complained of intermittent, sharp pains about the left eye and in the left side of the chest. Neurological examination revealed paresthesia and impaired perception of touch and pin-pricks in the dermatomes of Th8 and Th9 on the left side. In all four extremities, the muscle stretch reflexes were equal and slightly hyperactive, without weakness or sensory deficits. Metrizamide myelography showed defective filling at the level between the upper 8th and 9th thoracic vertebrae. The lesion was also demonstrated by computed tomography (CT) scan performed 1 hour later, appearing as an oval, radiolucent mass in the left dorsal spinal canal, which compressed the spinal cord forward and toward the right. Serial sections of the spinal canal revealed the lesion to be partly filled with contrast medium. Repeat CT scan 24 hours after metrizamide myelography showed more contrast medium in the periphery of the lesion, giving it a doughnut-shaped appearance. At surgery a smooth-surfaced cyst containing sebum and white hair was totally removed from the intradural extramedullary space. The histological diagnosis was dermoid cyst. There have been a few reported cases of intracranial epidermoid cyst in which filling of the cyst was suggested on metrizamide CT myelography. These findings may complicate the differential diagnosis of arachnoid cyst and dermoid or epidermoid cyst when only CT is used.

Analysis of lung tissue using ion beams

International Nuclear Information System (INIS)

Alvarez, J.L.; Barrera, R.; Miranda, J.

2002-01-01

In this work a comparative study is presented of the contents of metals in lung tissue from healthy patients and with lung cancer, by means of two analytical techniques: Particle Induced X-ray Emission (PIXE) and Rutherford Backscattering Spectrometry (RBS). The samples of cancerous tissue were taken from 26 autopsies made to individuals died in the National Institute of Respiratory Disease (INER), 22 of cancer and 4 of other non-cancer biopsies. When analyzing the entirety of the samples, in the cancerous tissues, there were increments in the concentrations of S (4%), K (635%), Co (85%) and Cu (13%). Likewise, there were deficiencies in the concentrations of Cl (59%), Ca (6%), Fe (26%) and Zn (7%). Only in the cancerous tissues there were appearances of P, Ca, Ti, V, Cr, Mn, Ni, Br and Sr. The tissue samples were classified according to cancer types (adenocarcinomas, epidermoides and of small cell carcinoma), personal habits (smokers and alcoholic), genetic predisposition and residence place. There was a remarkable decrease in the concentration of Ca and a marked increment in the Cu in the epidermoide tissue samples with regard to those of adenocarcinoma or of small cells cancer. Also, decrements were detected in K and increments of Fe, Co and Cu in the sample belonging to people that resided in Mexico City with regard to those that resided in the State of Mexico

Teoria della relatività ristretta

CERN Document Server

Ugarov, Vladimir Aleksandrovic

1982-01-01

Meccanica classica e principio di relatività ; postulati di Einstein, intervalo tra eventi, trasformazioni di Lorentz ; conseguenze della trasformazioni di Lorentz ; classificazione degli intervalli e principio di causalità, metodo del coefficiente k ; spazio-tempo quadridimensionale ; meccanica relativistica di una particella ; teoria di Maxwell in forma relativistica ; fenomeni ottici e teoria della relatività ristretta ; su alcuni "paradossi" della teoria della relatività ristretta ; supplementi ; eventi fondamentali della storia della TRR.

Módulos interactivos para el aprendizaje de la semántica.

OpenAIRE

Aquino Palacios, Ingrid

2012-01-01

Se proponen modulos interactivos para lograr el aprendizaje de la semantica en alumnos del V semestre de la Carrera de Lenguas, Literatura y Comunicacion de la Facultad de Educacion de la UNCP. Los metodos utilizados fueron el experimental y el bibliografico-documental. Los instrumentos utilizados fueron la prueba objetiva, prueba de ensayo y la prueba pedagogica. Se logró mejorar el aprendizaje de la semántica 

Bibliography of Books and Published Reports on Gas Turbines, Jet Propulsion, and Rocket Power Plants, January 1950 through December 1953

Science.gov (United States)

1953-12-01

75. Aeronautics In 1950. Engineer 191,67 and 100. Critical review of gas turbine progress in 1950. Engineer 191, 50. Gas turbines in 1950. Engineer 191...1952) ; Trans. ASME 75,121. A critical review of gas turbine progress, 1952. Engineer 195, 124. Aeronautics in 1952. Engineer 195, 24, 55 and 91...Physical fundamentals of jet propulsion. Forsch. Gebiete Ingenieurw. B19, Forschungaheft 437, p 5. 0. Santangelo, Metodo di calcolo delle

Technology and Power

Science.gov (United States)

2003-04-07

disappear and opponents will fight throughout the battlefield destroying critical points of command and control systems, logistical support and...with these problems. However, growth slumped to 3 percent in 2000. The Pakistani education sector is in a critical state of disarray. While substantial...Accessed 15 March 2003. Briones, Guillermo. Metodos y Técnicas de Investigación para las Ciencias Sociales, 3rd ed. Ciudad de México, México: Editorial

Grounding, Bonding, Shielding, and Lightning Bibliography 1972 to 1979

Science.gov (United States)

1981-02-01

Congress on Radiation Protection, May 3-5, 1972. For critical examination of incorporation in man besides the extensive medical evaluation it is...careful adherence to approved practices in critical areas. The ground- ing treatment is very brief, being limited to the most salient considera-1tions of...frequency are given. -58- - - I. Marongiu, " Metodo di Calcolo Semplificato della Resistenza di Terra di un Sistema di Dispersori Moiteplici Parallelo

Investigating the Mobility of Light Autonomous Tracked Vehicles using a High Performance Computing Simulation Capability

Science.gov (United States)

2012-08-01

of components and numerical outputs makes the results exceedingly difficult to in- terpret; consequently, rendering is a critical last step to the...output image and rendered indepen- dently. The REYES pipeline is illustrated in Fig. 13. Speed is another critical attribute of the render- ing...Methods and Applications, C. Bottasso, Ed. Springer, 2008, pp. 45–55. [33] TASORA, A., MANCONI, E., AND SILVESTRI, M. Un nuovo metodo del simplesso

Relative cytotoxicity of complexes of platinum(II and palladium(II against pure cell culture Paramecium caudatum and human cell lines A431 and HaCaT

Directory of Open Access Journals (Sweden)

Aleksei Vladimirovich Eremin

2018-04-01

Full Text Available The results of cytotoxicity cisplatin-like complexes of platinum(II and palladium(II are presented. The cytotoxicity was researched by method of  biotesting with Paramecium caudatum and by MTT-assay with human cells: epidermoid carcimoma A431 and minimal transformed aneuploid keratinocytes HaCaT. Cytotoxicity of complexes toward protists is high, however, comparatively HaCaT are more sensitive than A431. Furthemore, cytotoxicity of palladium(II complexes is higher than the analogues with platinum(II.

Il metodo mitico e i cattivi pensieri

Directory of Open Access Journals (Sweden)

Elio Franzini

2012-05-01

Full Text Available Moving from a definition of his « mythical method», the essay aims to outline the so-called «Philosophy of Art» of Paul Valéry. It sketches a portrait of the French author as an authentic philosopher of phenomenology able to define in a non-abstract way what must be intended with «aesthetics».

Le narrazioni come metodo di indagine sociologica

Directory of Open Access Journals (Sweden)

Rita Bichi

2012-04-01

Full Text Available L'incontro trentino ha dimostrato l'interesse crescente dei giovani sociologi per lo sviluppo dei metodi narrativi e la capacità che questi hanno di essere efficaci nell'analisi di svariati temi, dai racconti di malattia alle narrazioni identitarie, dallo studio di lavoro e organizzazioni a quello delle migrazioni, di genere e memoria. Tuttavia, l'interesse della sociologia italiana va visto in un quadro di sviluppo più ampio a livello europeo e americano dove, a partire dagli anni '90, l'intervento di alcuni autori come Lyotard, Bruner e Macintyre, ha sancito quella che alcuni autori hanno definito svolta narrativa. La sociologia, infatti, tende sempre più a valorizzare la narrazione come processo di conoscenza peculiare che è attivato costantemente nella vita quotidiana; la "rivoluzione" risiede nel fatto che la narrazione diventa oggetto della sociologia e la disciplina stessa valorizza il suo uso sia come strumento di indagine scientifica, sia come modo di conoscere che come modo di comunicare, rivendicando la legittimità scientifica all'ascolto della parola diretta degli individui coinvolti all'interno delle ricerche di stampo sociologico.

Genealogy of the body and genealogical body

Directory of Open Access Journals (Sweden)

Paola Cecchetti

2011-06-01

Full Text Available A partire da un quadro di Frida Kahlo intitolato I miei nonni, i miei genitori e io le due autrici indagano quel testo-immagine che sta all'origine dello stile di lettura del soggetto. Posto dinanzi alla stessa immagine, ciascuno ne fa una rappresentazione estremamente personale, un quadro delle proprie vicissitudini interne e dei legami transgenerazionali che lo hanno segnato. I momenti nei quali si articola la ricerca sono tre: la scrittura dell’occhio, il ricalco e il percorso della mano, il negativo e l’assenza.A essi segue poi lo psicodramma. Tale successione temporale abitua a vedere nell'immagine disegnata l'immagine negata, assente. L'esperienza sembra aver creato un nuovo metodo di indagine della psiche rispetto al transgenerazionale, metodo che intreccia il genogramma (di origini sistemico-relazionale e lo psicodramma analitico, e che viene chiamato “genodramma psicoanalitico”. Partendo da un dato clinico – l'esilità del legame che le nuove generazioni intrattengono con quelle che le precedono, sembra vogliano rinegoziare il contratto narcisistico che assegna al passato il posto dell'assenza. Il contributo si chiude con un interrogativo: “Alla ricerca di che cosa? Della presenza o, meglio, delle tracce lasciate nel soggetto dall'Altro che precede l'insediamento dell'Io”.

Efecto neutralizador del extracto acuoso de Dracontium loretense (JERGÓN SACHA sobre la actividad letal del veneno de Bothrops atrox

Directory of Open Access Journals (Sweden)

Amanda Lovera

2006-07-01

Full Text Available Objetivo: Determinar la capacidad del extracto acuoso D. loretense (jergon sacha para neutralizar la actividad letal del veneno de la serpiente B. atrox. Materiales y metodos: Se realizo el screening fitoquimico del extracto acuoso del bulbo desecado de D. loretense, se calculo la dosis letal 50(DL50 para el extracto y el veneno de B. atrox. Luego se realizaron enfrentamientos de diferentes dosis de extracto y veneno inyectadas intraperitonealmente en ratones, previa incubacion, para calcular la dosis eficaz 50% (DE50 del extracto para neutralizar el efecto letal del veneno por el metodo de Probits. Resultados: El analisis fitoquimico del extracto permitio identificar compuestos fenolicos, taninos, saponinas, proteinas, terpenoides y esteroides. No sobrevivio ningun raton que recibio el veneno sin D. loretense, y no fallecio ninguno al que se le dio solo el extracto acuoso de D. loretense. Se determino la DE50 en 91,15 µg/raton del extracto para neutralizar 2DL50 del veneno. Se encontro que a mayor dosis del veneno de B.atrox se necesito menores dosis del extracto acuoso de D. loretense. Conclusiones: el extracto acuoso de D. loretense neutraliza la actividad letal de veneno de B. atrox. Es necesario realizar estudios que permitan identificar los metabolitos del extracto que tienen esta accion.

La capa de ozono

OpenAIRE

Sánchez Vega, Marco Vinicio

2016-01-01

El ozono estratosférico (O3) es un gas que forma una capa que nos protege de la radiación ultravioleta tipo B (UV-B), perjudicial para la vida en el planeta. La capa de ozono se encuentra en la estratosfera. La cantidad de ozono se ve disminuida debido a su reacción con contaminantes de origen humano. Entre los contaminantes más perjudiciales para la capa de ozono se encuentran: los clorofluorocarbonos (CFCs), el gas metano (CH4), el óxido nitroso, el monóxido de cloro (ClO), entre otros. La ...

The Role of Non-Destructive Testing in the Los Alamos Reactor Programme; Role des Essais Non Destructifs dans le Programme de Reacteurs de los Alamos; Rol' nedestruktivnykh ispytanij materialov v Los-Alamosskoj reaktornoj programme; Papel de los Metodos de Ensayo No Destructivo en el Programa de Reactores de Los Alamos

Energy Technology Data Exchange (ETDEWEB)

Tenney, G. H. [University of California, Los Alamos Scientific Laboratory, Los Alamos, NM (United States)

1965-10-15

temperature UHTREX, actuellement en construction, on a etudie par microiadiogiaphie et au moyen de microscopes electroniques des grains de carbure d'uranium enrobes de carbone pyrolytique, d'un diametre de 150 {mu}m, pour evaluer la translocation de l'uranium en fonction de la temperature. On determine la quantite et l'uniformite de la charge d'uranium dans les elements au graphite d'UHTREX au moyen de compteurs a scintillation specialement concus. Environ 90% des travaux effectues a ce sujet n'ont encore fait l'objet d'aucune publication. (author) [Spanish] El Laboratorio Cientifico de Los Alamos, explotado por la Universidad de California por encargo de la Comision de Energia Atomica de los Estados Unidos, viene ocupandose desde hace mas de veinte afios del proyecto, diseno y construccion de reactores nucleares de cuatro tipos generales; a saber, de investigacion, de potencia, de propulsion espacial y para conjuntos criticos. El llamado Grupo de ensayos no destructivos colabora practicamente en todas las actividades y proyectos del laboratorio. En la presente memoria se exponen algunos de los metodos de ensayo no destructivo y sus aplicaciones, establecidos para uso en el programa de reactores. El programa LAPRE (Los Alamos Power Reactor Experiment) se basa en el empleo de una solucion de fosfato de uranio a alta temperatura. La solucion es muy corrosiva y todas las piezas que entren en contacto con ella deben ir revestidas de oro. Durante el proceso de produccion de chapa de oro laminada a partir de lingotes, se han utilizado procedimientos radiograficos especiales para inspeccionar el metal. Las juntas soldadas se examinaron del mismo modo, y ademas se establecio un metodo para comprobar la presencia de impurezas incrustadas en la superficie de la chapa de oro. El concepto fundamental en que se basa el programa LAMPRE (Los Alamos Molten Plutonium Reactor Experiment) es la utilizacion como combustible de plutonio metalico liquido en vez de solido. El combustible esta

Optimizacija procesnih parametrov za stabilizacijo in izboljšanje sposobnosti struženja

OpenAIRE

Mlinar, Andrej

2017-01-01

Magistrska naloga obravnava proizvodni proces izdelka z ozkim tolerančnim območjem. V procesu izdelave se je pojavil problem nestabilnosti obdelovalnega procesa. Pred analizo obdelovalnega procesa smo najprej z metodo analize merilnega sistema preverili merilni proces. Po preverjanju ustreznosti merilnega procesa smo v nadaljevanju preverili obstoječi obdelovalni proces. Iz analize statistične kontrole procesa obstoječega stanja smo ugotovili, da je proces potrebno stabilizirati. Za stabiliza...

SIGMA Experimental Facility

International Nuclear Information System (INIS)

Rivarola, Martin; Florido, Pablo; Gonzalez, Jose; Brasnarof, Daniel; Orellano, Pablo; Bergallo, Juan

2000-01-01

The SIGMA ( Separacion Isotopica Gaseosa por Metodos Avanzados) concept is outlined.The old gaseous diffusion process to enrich uranium has been updated to be economically competitive for small production volumes.Major innovations have been introduced in the membrane design and in the integrated design of compressors and diffusers.The use of injectors and gas turbines has been also adopted.The paper describes the demonstration facility installed by the Argentine Atomic Energy Commission

La prolusione di rocco e le dottrine del processo penale

OpenAIRE

Renzo Orlandi

2015-01-01

L’articolo analizza le conseguenze del pensiero giuridico di Arturo Rocco, dal 1910 nella dottrina di procedura penale, ossia, il metodo tecnico-giuridico (esegesi, sistematica e critica). La dogmatica di procedura pena- le inizia con la monografia di Giovanni Conso, nel 1955. L’insoddisfazione con il tecnicismo giuridico e con la mancanza di maturità scientifica si è manifestata con Carnelutti nel 1946 (Cerenterola), sottolineando le peculiarità strutturali del procedimento penale. In questa...

SIGMA Experimental Facility; Facilidad Experimental SIGMA

Energy Technology Data Exchange (ETDEWEB)

Rivarola, Martin; Florido, Pablo; Gonzalez, Jose; Brasnarof, Daniel; Orellano, Pablo; Bergallo, Juan [Comision Nacional de Energia Atomica, Centro Atomico Bariloche, Grupo de Disenos Avanzados y Evaluacion Economica, Complejo Tecnologico Pilcaniyeu (Argentina)

2000-07-01

The SIGMA ( Separacion Isotopica Gaseosa por Metodos Avanzados) concept is outlined.The old gaseous diffusion process to enrich uranium has been updated to be economically competitive for small production volumes.Major innovations have been introduced in the membrane design and in the integrated design of compressors and diffusers.The use of injectors and gas turbines has been also adopted.The paper describes the demonstration facility installed by the Argentine Atomic Energy Commission.

Caratterizzazione biomolecolare di Clostridi isolati da latte e formaggi

OpenAIRE

Demarco, Fabiana

2006-01-01

Il latte è una miscela complessa di sostanze di notevole importanza biologica e nutrizionale (proteime, grassi, lattosio, vitamine, sali, etc.) e costituisce, da solo un sistema dietetico bilanciato e capace di favorire la moltiplicazione della flora intestinale simbiotica. E’ ampiamente utilizzato sia tal quale nella preparazione del cibo, sia trasformato, da solo, o in combinazione con altri alimenti. Il formaggio, che rappresenta il più antico e valido metodo conosciuto dall’uomo per co...

Computational Methods for Aerodynamic Design (Inverse) and Optimization

Science.gov (United States)

1990-01-01

min minimum pressure coefficient cp* critical pressure coefficient Th mass flow through nacelle M Mach number Q, u velocity QPU, QPL upper and lower...Airfoils with Given Velocity Distribution in Incompressible Flow," J. Aircraft, Vol. 10, 1973, pp. 651-659. 7. Polito, L., "Un Metodo Esatto -per 11 Progetto...however, a modification in the definition of the critical pressure coefficient is applied. The relevant formulas are derived from those applied in the

Analysis of the nonlinear dynamic behavior of power systems using normal forms of superior order; Analisis del comportamiento dinamico no lineal de sistemas de potencia usando formas normales de orden superior

Energy Technology Data Exchange (ETDEWEB)

Marinez Carrillo, Irma

2003-08-01

of the generator and criteria and procedures are proposed to interpret the phenomenon of modal interaction. [Spanish] Esta tesis investiga la aplicacion de metodos de analisis de perturbacion de parametros en la teoria de sistemas dinamicos no lineales, al estudio de la estabilidad de pequena senal de sistemas electricos de potencia. El trabajo se centra en la determinacion de dos aspectos fundamentales de interes en el estudio del comportamiento dinamico no lineal del sistema: la caracterizacion y cuantificacion del grado de la interaccion no lineal entre los modos fundamentales de oscilacion del sistema y el estudio de los modos con mayor influencia en la respuesta del sistema ante perturbaciones pequenas. Con estos objetivos, se propone un modelo matematico general, basado en la aplicacion de la expansion en series de potencia del modelo no lineal del sistema de potencia y la teoria de formas normales de capos vectoriales para el estudio del comportamiento dinamico del sistema de potencia. La herramienta propuesta generalizada los metodos existentes en la literatura para considerar efectos de orden superior en el modelo dinamico del sistema de potencia. Partiendo de esta representacion, se propone una metodologia para obtener soluciones analiticas de lazo cerrado y se investiga la extension de los metodos existentes para identificar y cuantificar el grado de interaccion entre los modos fundamentales de oscilacion del sistema. La herramienta desarrollada permite, a partir de expresiones analiticas de lazos cerrado, el desarrollo de medidas analiticas para evaluar el grado de estres en el sistema, la interaccion entre los modos fundamentales de oscilacion y la determinacion de fronteras de estabilidad. El desarrollo conceptual del metodo propuesto en esta tesis ofrece, por otra parte, una gran flexibilidad para incorporar modelos detallados del sistema de potencia y la evaluacion de diversas medidas de la interaccion modal no lineal. Por ultimo, se presenta los

Predictive factors for the response of pulmonary tumours treated by robotic stereotactic radiotherapy; Facteurs predictifs pour la reponse des tumeurs pulmonaires traitees par radiotherapie stereotaxique robotisee

Energy Technology Data Exchange (ETDEWEB)

Doyen, J.; Benezery, K.; Thariat, J.; Angellier, G.; Poudenx, M.; Bondiau, P.Y. [Centre Antoine-Lacassagne, 06 - Nice (France); Beckendorf, V. [Centre Alexis-Vautrin, 54 - Nancy (France); Venissac, N. [Centre hospitalo-universitaire Pasteur, 06 - Nice (France)

2010-10-15

The authors report a study which aimed at identifying factors influencing the response to radiotherapy performed in robotic stereotactic conditions with CyberKnife within the frame of treatment of primitive or secondary pulmonary tumours. Thirty eight stage I cancers, 22 metastases including 17 epidermoid carcinomas, and 43 adenocarcinomas have been treated this way. The analysis of data and results reveals that feminine gender, a biological dose greater than 140 Gy, and an age greater than 65 year old are associated with a better tumour response. Short communication

Reconstrucción de cuero cabelludo con colgajo libre de omentum Reconstruction of the scalp with a free flap of omentum

OpenAIRE

C. Navarro Cuellar; F. Riba García; B. Guerra Martínez; R. Pujol Romanya; H. Herencia Nieto; C. Navvarro Vila

2004-01-01

Los defectos de cuero cabelludo pueden tener una etiología diversa. Resecciones oncológicas, lesiones postraumáticas e infecciosas pueden dar lugar a diferentes defectos en cuanto a tamaño y extensión. Para su reconstrucción disponemos de múltiples técnicas quirúrgicas como colgajos locales, regionales y expansores titulares. No obstante, para defectos extensos los colgajos libres son la única posibilidad reconstructiva. Presentamos el caso de un paciente con carcinomas epidermoides multicént...

Fabrication of magnetite-based core–shell coated nanoparticles with antibacterial properties

International Nuclear Information System (INIS)

Grumezescu, A M; Ficai, A; Vasile, O R; Cristescu, R; Dorcioman, G; Socol, G; Mihailescu, I N; Chifiriuc, M C; Mihaiescu, D E; Enculescu, M; Chrisey, D B

2015-01-01

We report the fabrication of biofunctionalized magnetite core/sodium lauryl sulfate shell/antibiotic adsorption-shell nanoparticles assembled thin coatings by matrix assisted pulsed laser evaporation for antibacterial drug-targeted delivery. Magnetite nanoparticles have been synthesized and subsequently characterized by transmission electron microscopy and x-ray diffraction. The obtained thin coatings have been investigated by FTIR and scanning electron microscope, and tested by in vitro biological assays, for their influence on in vitro bacterial biofilm development and cytotoxicity on human epidermoid carcinoma (HEp2) cells. (paper)

Annual Research Progress Report for Department of Clinical Investigation (Madigan Army Medical Center), October 1990 - September 1991

Science.gov (United States)

1991-09-01

Protocol for a Multicenter Study for thýe Treatment 47 190,091 of Central Precocious Puberty with D-Trp(6)-Des-Gly(10)-N- ethylamide-LHRH, A Long-Acting...Analog of Luteinizing Herr-,"ne Releasing.... Moore DC 0 Characterization of LiI Isoform.i in Treatl and Untreated 48 n91� Precocioas Puberty Moore DC...Epidermoid Carcinoma of the Penis , Phase II 33 Index To Protocols (cont’d) PI and No. &AM Davidson H C SWOG 8573: Treatment of Limited Small Cell Lung

Antenatal sonographic appearance of a large orbital encephalocele: a case report and differential diagnosis of orbital cystic mass.

Science.gov (United States)

Ahmed, Ahmed; Noureldin, Rehab; Gendy, Mohamed; Sakr, Sharif; Abdel Naby, Mahmoud

2013-06-01

Orbital meningoceles and encephaloceles are rare extracranial extensions of the brain and meninges with or without direct communication between the central nervous system and the abnormal mass. We reported a rare case of large fetal orbital encephalocele; the diagnosis was suspected initially by prenatal ultrasound and confirmed by postnatal MRI and CT scans. The differential diagnosis of an intrauterine fetal cystic orbital mass includes orbital teratoma, epidermoid inclusion cysts, hemangioma or lymphangioma, congenital cystic eye, dacryocystocele, and orbital cephalocele. Copyright © 2012 Wiley Periodicals, Inc.

Linear-quadratic model predictions for tumor control probability

International Nuclear Information System (INIS)

Yaes, R.J.

1987-01-01

Sigmoid dose-response curves for tumor control are calculated from the linear-quadratic model parameters α and Β, obtained from human epidermoid carcinoma cell lines, and are much steeper than the clinical dose-response curves for head and neck cancers. One possible explanation is the presence of small radiation-resistant clones arising from mutations in an initially homogeneous tumor. Using the mutation theory of Delbruck and Luria and of Goldie and Coldman, the authors discuss the implications of such radiation-resistant clones for clinical radiation therapy

Analysis and evaluation of the main factors that influence the growing of the electrical power consumption in the national electrical sector, period 2000-2005; Analisis y evaluacion de los principales factores que influyen en el crecimiento del consumo de energia electrica en el sector electrico nacional, periodo 2000-2005

Energy Technology Data Exchange (ETDEWEB)

Aguilar Luna, Luis Miguel

2008-06-15

de potencia (CUFP). Ademas, se desarrolla en esta tesis las ecuaciones utilizadas en el Jacobiano del metodo Newton-Raphson, para resolver flujos de potencia incluyendo los dispositivos SIFLETCA. Se muestra diferentes aplicaciones que se tienen al instalar un dispositivo, tales como prevencion de flujos en anillo, barrera electronica, incremento en la capacidad de transmision y especificacion del flujo de potencia en lineas de transmision. Por otra parte, se desarrolla en la tesis un analisis de sensibilidades de un sistema de potencia en estado estacionario. Tambien se proponen en la tesis los parametros de control para los cuales se calcula las sensibilidades. Asimismo, se utiliza un indice de desempeno para medir el grado de congestion de un sistema electrico. Al calcular las sensibilidades se utiliza los resultados obtenidos de los flujos de potencia. Se usa 4 redes electricas para encontrar donde se debe situar cada dispositivo SIFLETCA para reducir la congestion en el sistema. Tambien, se compara el metodo desarrollado en la tesis con un metodo de sensibilidades que emplea flujos de CD para validacion y mostrar las ventajas de usar el metodo Newton en flujos de potencia.

Calculation of sensitivities in electrical systems with SIFLETCA devices; Calculo de sensibilidades en sistemas electricos con dispositivos SIFLETCA

Energy Technology Data Exchange (ETDEWEB)

Rubio Marroquin, Gabriel Omar

2004-03-15

de potencia (CUFP). Ademas, se desarrolla en esta tesis las ecuaciones utilizadas en el Jacobiano del metodo Newton-Raphson, para resolver flujos de potencia incluyendo los dispositivos SIFLETCA. Se muestra diferentes aplicaciones que se tienen al instalar un dispositivo, tales como prevencion de flujos en anillo, barrera electronica, incremento en la capacidad de transmision y especificacion del flujo de potencia en lineas de transmision. Por otra parte, se desarrolla en la tesis un analisis de sensibilidades de un sistema de potencia en estado estacionario. Tambien se proponen en la tesis los parametros de control para los cuales se calcula las sensibilidades. Asimismo, se utiliza un indice de desempeno para medir el grado de congestion de un sistema electrico. Al calcular las sensibilidades se utiliza los resultados obtenidos de los flujos de potencia. Se usa 4 redes electricas para encontrar donde se debe situar cada dispositivo SIFLETCA para reducir la congestion en el sistema. Tambien, se compara el metodo desarrollado en la tesis con un metodo de sensibilidades que emplea flujos de CD para validacion y mostrar las ventajas de usar el metodo Newton en flujos de potencia.

Soil Moisture Measurement through Time Domain Reflectometry (TDR). Irrigation Application; Medicion de la humedad del suelo por reflectometria en el dominio temporal (TDR). Aplicacion en irrigacion

Energy Technology Data Exchange (ETDEWEB)

Quinonez Pedroza, Hector E.; Ruelle, Pierre; Nemeth Ildiko [Cemagre, (France)

2002-03-01

limitado debido a que estos metodos afrontan seros problemas (elevados costos de los lisimetros y del aspersor de neutrones, asi como se severa reglamentacion y el rango de validez limitado de los tensiometros, etcetera) que dificultan sus generalizacion, ademas, las mediciones de tales metodos generalmente son puntuales y discontinuas. La reflectometria en el dominio temporal (TDR) se presenta como una alternativa viable a tales metodos por su precision y por la continuidad de las mediciones. En el presente trabajo se presenta la evaluacion de la humedad del suelo por el metodo neutronico y TDR en un cultivo de maiz irrigado por gravedad en surcos cerrados. Los resultados muestran que si bien las determinaciones absolutas de la humedad presentan diferencias en los perfiles de 30 a 90 cm, las variaciones de la humedad son similares en todos los casos y responden de manera consecuente con los aportes de agua a la evapotranspiracion. Se pone de manifiesto la limitacion del aspersor de neutrones por la discontinuidad de las mediciones, en contraste con la continuidad de la TDR, que permite el analisis detallado de los fenomenos de infiltracion y evapotranspiracion a escalas instantaneas de tiempo.

Estudio preliminar del ganglio centinela en el cáncer oral: a propósito de 12 casos Preliminary study of the sentinel node in oral cancer: in conjunction with 12 cases

Directory of Open Access Journals (Sweden)

C.I. Salazar Fernandez

2004-06-01

Full Text Available Resumen: El manejo de los cuellos N0 en pacientes con carcinoma epidermoide de cabeza y cuello es controvertido. Objetivo. Demostrar la eficacia diagnóstica de la biopsia del ganglio centinela (GC en los pacientes con carcinoma epidermoide oral con cuello clinicamente negativo. Metodología. Se realiza un estudio prospectivo de 12 pacientes consecutivos, hasta el momento, con carcinoma epidermoide oral de cualquier tamaño y cuello clinicamente negativo que no habian recibido tratamiento antitumoral, asistidos en el S. de Cirugía Maxilofacial del área del H.U.V.M de Sevilla. A estos pacientes se les realiza una linfografía cervical con nanocoloides -Tc 99 para localizar el GC, y una dosis de recuerdo antes de iniciar el ttº quirúrgico. Durante la cirugía se localiza el GC con la sonda y se extirpa, se completa la disección cervical funcional y la extirpación de la lesión con posteriores estudios histológicos independientes. Resultados. índice de linfolocalización: 91%, índice de radiolocalización 100%, falsos negativos 0%, la sensibilidad y VPN del 100%, cocientes de probabilidades positivo > 10 y negativo Abstract: IManagement of the N0 neck in patients with head and neck squamous cell carcinoma remains controversial. Objective. To evaluate the feasibility and predictive ability of the sentinel node (SN localization-biopsy technique for patients with squamous cell carcinoma of the oral cavity and clinically negative necks. Methodology. We realize a prospective study of 12 consecutive patients at present, with squamous cell carcinoma oral and clinically negative necks. These patients had not recived treatment against tumor and they were assited by Maxillofacial Surgery Service of HUVM from Seville. All patients received a cervical Tc99mlymphoscintigraphy to localize the sentinel node and a new dose before surgery. Intraoperatively, the sentinel node is localized and it is removed separately before tumor resection and elective

Factors affecting ultraviolet-A photon emission from β-irradiated human keratinocyte cells.

Science.gov (United States)

Le, M; Mothersill, C E; Seymour, C B; Ahmad, S B; Armstrong, A; Rainbow, A J; McNeill, F E

2015-08-21

The luminescence intensity of 340±5 nm photons emitted from HaCaT (human keratinocyte) cells was investigated using a single-photon-counting system during cellular exposure to (90)Y β-particles. Multiple factors were assessed to determine their influence upon the quantity and pattern of photon emission from β-irradiated cells. Exposure of 1 x 10(4) cells/5 mL to 703 μCi resulted in maximum UVA photoemission at 44.8 x 10(3)±2.5 x 10(3) counts per second (cps) from live HaCaT cells (background: 1-5 cps); a 16-fold increase above cell-free controls. Significant biophoton emission was achieved only upon stimulation and was also dependent upon presence of cells. UVA luminescence was measured for (90)Y activities 14 to 703 μCi where a positive relationship between photoemission and (90)Y activity was observed. Irradiation of live HaCaT cells plated at various densities produced a distinct pattern of emission whereby luminescence increased up to a maximum at 1 x 10(4) cells/5 mL and thereafter decreased. However, this result was not observed in the dead cell population. Both live and dead HaCaT cells were irradiated and were found to demonstrate different rates of photon emission at low β activities (⩽400 μCi). Dead cells exhibited greater photon emission rates than live cells which may be attributable to metabolic processes taking place to modulate the photoemissive effect. The results indicate that photon emission from HaCaT cells is perturbed by external stimulation, is dependent upon the activity of radiation delivered, the density of irradiated cells, and cell viability. It is postulated that biophoton emission may be modulated by a biological or metabolic process.

Influencia del solvente en el espectro ultravioleta de nitro y amino bifenilos

Directory of Open Access Journals (Sweden)

María Cristina B. de Gómez

2009-07-01

Full Text Available Los nitro y amino bifenilos fueron sintetizados, caracterizados y usados como solutos, para determinarles su espectro U.V. Los solventes empleados corresponden a la serie de los alcoholes, como son: Metanol, Etanol, n- e iso-Propanol, n-, iso- y sec-Butanol. Se encontró que la posición de la banda de máxima absorción de cada una de las soluciones se relaciona tanto con las características del soluto como del solvente. Estos efectos se resumen en la ecuación de Rao (12, cuya aplicabilidad queda confirmada para este caso.

Impact of tumor extent and location on treatment outcome in patients with stage III non-small cell lung cancer treated with radiation therapy

International Nuclear Information System (INIS)

Hayakawa, Kazushige; Mitsuhashi, Norio; Saito, Yoshihiro

1996-01-01

The results of treatment of 141 patients with stage III non-small cell lung cancer (NSCLC) who received definitive radiation therapy at Gunma University Hospital between 1976 and 1989 were retrospectively analyzed. Radiation was given with standard fractionation for a planned prophylactic dose of 40 Gy over 4 weeks and a definitive dose of 60 Gy over 6 weeks or more. The two- and five-year survival rates were 27% and 12% for stage IIIA, and 18% and 8% for stage IIIB, respectively (P=0.052). By univariate analysis, a primary tumor less than 5 cm in diameter was also an important predictor of survival (P=0.008). As for tumor location, the patients with primary tumors in the upper lobes or the superior segment of the lower lobes of the lung lived longer than those with primary tumors at any other site (P=0.032). Patients with epidermoid carcinoma had a higher survival rate at 5 years than those with other histologic types (14% vs 3%, P=0.074). Multivariate analysis showed that among tumor characteristics, the site of the primary tumor, the pattern of tumor spread and N stage were significantly associated with overall survival. Among the patients with stage III NSCLC, those with stage IIIA epidermoid carcinoma in the upper lobe or the superior segment of the lower lobe of the lung were considered to be the most favorable candidates for definitive radiation therapy. (author)

Endostatin improves radioresponse and blocks tumor revascularization after radiation therapy for A431 xenografts in mice

International Nuclear Information System (INIS)

Itasaka, Satoshi; Komaki, Ritsuko; Herbst, Roy S.; Shibuya, Keiko; Shintani, Tomoaki D.D.S.; Hunter, Nancy R. M.S.; Onn, Amir; Bucana, Corazon D.; Milas, Luka; Ang, K. Kian; O'Reilly, Michael S.

2007-01-01

Purpose: Clinical trials of antiangiogenic agents used alone for advanced malignancy have been disappointing but preclinical studies suggest that the addition of radiation therapy could improve antitumor efficacy. To test the hypothesis that antiangiogenic therapy combined with radiation therapy can overcome the limitations of antiangiogenic monotherapy, we studied the effects of endostatin combined with radiation on the growth and vascularization of A431 human epidermoid carcinomas growing intramuscularly in the legs of mice. Methods and Materials: Mice with established A431 human epidermoid leg tumors were treated with radiation, endostatin, both radiation and endostatin, or vehicle control. The experiment was repeated and mice from each group were killed at 2, 7, and 10 days after irradiation so that tumor tissue could be obtained to further analyze the kinetics of the antitumor, antivascular, and antiangiogenic response to therapy. Results: Endostatin enhanced the antitumor effects of radiation, and prolonged disease-free survival was observed in the combined treatment group. Endothelial cell proliferation was increased in tumors after irradiation but was blocked by the concurrent administration of endostatin, and the combination of endostatin with radiation enhanced endothelial cell apoptosis within 48 h after irradiation. Expression of vascular endothelial growth factor, interleukin-8, and matrix metalloproteinase-2 were increased in tumors after irradiation, and this increase was blocked by concurrent administration of endostatin. Conclusion: These data indicate that endostatin can block tumor revascularization after radiation therapy and thereby augment radioresponse

Ultrasonographic findings of benign soft tissue tumors

International Nuclear Information System (INIS)

Kim, Ki Sung; Oh, Dong Heon; Jung, Tae Gun; Kim, Yong Kil; Kwon, Jung Hyeok

1994-01-01

To clarify the characteristic sonographic features of benign soft tissue tumors and to evaluate the usefulness of sonographic imaging. We retrospectively reviewed ultrasonographic images of 70 cases in 68 patients with histologically proved benign soft tissue tumors. The tumors include 33 lipomas, 11 hemangiomas, 11 lymphangiomas, 7 neurilemmomas, 4 epidermoid cysts, 2 fibromas, 1 mesenchymoma, and 1 myxoma. The sonographic appearances of the lesions were mainly solid in 53 cases(33 lipomas, 8 hemangiomas, 2 lymphangiomas, 7 neurilemmomas, 2 fibromas and 1 mesenchymoma), mainly cystic in 14 cases(1 hemangioma, 8 lymphangiomas, 4 epidermoid cysts, and 1 myxomal), and mixed in 3 cases(2 hemangiomas and 1 lymphangioma). Although an accurate histologic prediction could not be made in most cases, certain patterns appeared to be characteristic of specific tumor types. 26 cases(78%) of lipoma were seen as lentiform, iso- or hyperechoic, solid mass. Hemangioma had variable appearance and characteristic calcifications were seen in 3 cases. Unicameral or multiseptated cystic mass with variable thickness of echogenic septa and solid portion was the characteristic finding of lymhangioma. Neurilemmoma showed lobulated, oval to round , relatively hypoechoic mass or with without internal cystic portion. Sonographic evaluation of benign soft tissue tumors is useful in demonstrating the location, size, extent, and internal characteristic of the mass. A relatively confident diagnosis can made when the characteristic features of the benign soft tissue tumor are present on sonographic imaging

Ultrasonographic findings of benign soft tissue tumors

Energy Technology Data Exchange (ETDEWEB)

Kim, Ki Sung; Oh, Dong Heon; Jung, Tae Gun; Kim, Yong Kil; Kwon, Jung Hyeok [Dongkang Genernal Hospital, Ulsan (Korea, Republic of)

1994-05-15

To clarify the characteristic sonographic features of benign soft tissue tumors and to evaluate the usefulness of sonographic imaging. We retrospectively reviewed ultrasonographic images of 70 cases in 68 patients with histologically proved benign soft tissue tumors. The tumors include 33 lipomas, 11 hemangiomas, 11 lymphangiomas, 7 neurilemmomas, 4 epidermoid cysts, 2 fibromas, 1 mesenchymoma, and 1 myxoma. The sonographic appearances of the lesions were mainly solid in 53 cases(33 lipomas, 8 hemangiomas, 2 lymphangiomas, 7 neurilemmomas, 2 fibromas and 1 mesenchymoma), mainly cystic in 14 cases(1 hemangioma, 8 lymphangiomas, 4 epidermoid cysts, and 1 myxomal), and mixed in 3 cases(2 hemangiomas and 1 lymphangioma). Although an accurate histologic prediction could not be made in most cases, certain patterns appeared to be characteristic of specific tumor types. 26 cases(78%) of lipoma were seen as lentiform, iso- or hyperechoic, solid mass. Hemangioma had variable appearance and characteristic calcifications were seen in 3 cases. Unicameral or multiseptated cystic mass with variable thickness of echogenic septa and solid portion was the characteristic finding of lymhangioma. Neurilemmoma showed lobulated, oval to round , relatively hypoechoic mass or with without internal cystic portion. Sonographic evaluation of benign soft tissue tumors is useful in demonstrating the location, size, extent, and internal characteristic of the mass. A relatively confident diagnosis can made when the characteristic features of the benign soft tissue tumor are present on sonographic imaging.

[Microsatellite instability and human papilloma virus genotypes in preneoplastic and neoplastic uterine cervix lesions].

Science.gov (United States)

Roa S, Juan Carlos; Martínez S, Ricardo; Montenegro, Sonia; Roa E, Iván; Capurro V, Italo; Ibacache S, Gilda; Melo A, Angélica

2007-01-01

The association between some specific human papilloma virus (HPV) types and cervix cancer is well known. However, the genetic conditions that favor the development of cervical cancer are less well known. To determine the presence of satellite instability (MSI) in preneoplastic and neoplastic lesions of the cervix and correlate these findings with HPV genotypes. Biopsy samples of cervical lesions were studied. Sixteen had low grade lesions, 22 had high grade lesions and 28 had an epidermoid cancer. Viral types were identified with polymerase chain reaction, dot-blot hybridization and restriction fragment length polymorphism. MSI was determined using a panel of eight highly informative microsatellites. Microsatellite instability in at least one locus was observed in 91, 56 and 69% of low grade lesions, high grade lesions and epidermoid carcinomas, respectively. MSI-High grade, MSI-Low grade instability and microsatellite stability were observed in 5, 60 and 46% of samples, respectively. Two of three samples with high grade instability had HPV 52 genotype. Other viral subtypes had frequencies that ranged from 78% to 100%, with the exception of HPV16 that was present in only 53% of samples with low grade instability. Two thirds of biopsy samples from cervical lesions had MSI, mechanism that can be involved in the first stages of cervical carcinogenesis. The low frequency of high grade instability, its association with HPV52 and the low frequency of HPV16 in samples with low grade instability, suggest different coadjutant mechanisms in cervical carcinogenesis.

Malignant tumors arising in the maxillary region after radiation therapy

International Nuclear Information System (INIS)

Shimizu, Sawamichi; Shirahata, Yuichi; Uchida, Yutaka

1984-01-01

Although radiotherapy has proven of great therapeutic value in the treatment of malignant tumors, it should also be borne in mind that radiation has a serious potential risk of giving rise to a secondary malignancy. We recently experienced 2 cases each of carcinoma and sarcoma arising in the irradiated areas long after radiation therapy for malignant tumors. In these 4 cases, 2 males and 2 females, the primary neoplastic diseases were squamous cell carcinoma, epidermoid carcinoma, carcinoma of unknown pathology and malignant lymphoma, and the secondary tumors were epidermoid carcinoma, squamous cell carcinoma, osteosarcoma and chondrosarcoma, respectively. The sites of occurrence of these malignancies were invariably in the maxillary region; the mean latent period was 15 years, aside from an infantile case with a latent period of 5 years. In view of the primary diseases being malignant tumors the following criteria were set up for the diagnosis of radiation-induced malignancies: (1) the site of occurrence is within the confines of a previously irradiated area, (2) the latent period is prolonged and (3) the malignancy occurs as a double tumor. Therapy was primarily by operation. The prognosis was exceedingly ominous, the average survival time being 22 months. This was probably and mainly because of rapidity of tumor growth. Thus, the secondary tumors had already spread back to inward by the time they were first discovered. This should be kept in mind during a long-term follow-up of patients receiving radiotherapy for malignancy. (author)

Seismic pressure effect on retaining walls; Presiones generadas por sismo en muros de retencion

Energy Technology Data Exchange (ETDEWEB)

Bonola, Isaac; Aviles, Javier [Instituto Mexicano de Tecnologia del Agua, Jiutepec, Morelos (Mexico)

2006-04-15

Retaining walls are auxiliary works used in different hydraulic structures. In seismically active areas, the dynamic pressures generated by the backfill must be appropriately evaluated at the design stage. Currently, a number of methods for estimating the seismic response of this type of works are available; however, most of them are simplified and not all the parameters involved have been examined. In this paper, a hybrid boundary and finite element method is presented for gravity walls in which the backfill can be represented by a horizontally layered medium. The effect of lateral extension of the backfill can be included in the model by introducing a vertical boundary coupling the movement of the backfill with that of the surrounding soil. The wave propagation analysis in the layered medium is carried out for both horizontal and vertical harmonic excitation; the latter excitation may cause important responses under certain situations. To illustrate the applicability of the proposed method, results for two numerical examples are presented: one for dry backfill and other for saturated backfill, considering in both cases the variations of dynamic properties of the soil with the depth. [Spanish] Los muros de retencion son estructuras auxiliares utilizadas en distintas obras hidraulicas. En zonas sismicas, las presiones dinamicas generadas por el relleno deben evaluarse adecuadamente en la etapa de diseno. Actualmente existen numerosos metodos para estimar la respuesta sismica de este tipo de estructuras; sin embargo, la mayoria de ellos son simplificados y no todos los parametros involucrados han sido examinados. En este trabajo se presenta un metodo hibrido de frontera y elemento finito para muros de gravedad en el que el relleno puede representarse por un medio estratificado horizontalmente. En el modelo puede incluirse el efecto de la extension lateral del relleno, introduciendo una frontera vertical que acopla el movimiento del relleno con el del suelo

Pressure surge generated by start up of pumping equipment in pipes to pressure. Application to a real case; Transitorios hidraulicos generados por arranque de equipo de bombeo en conducciones a presion. Aplicacion a un caso real

Energy Technology Data Exchange (ETDEWEB)

Carmona Paredes, L.G.; Carmona Paredes, R.B. [Instituto de Ingenieria, UNAM, Mexico, D.F. (Mexico)

2000-12-01

Water closed conduits are commonly designed with special attention paid to pressure surges due to pumping failures. In some particular cases, such at the Rio Yaqui-Guaymas water pipeline system, pressure surges due to pumping start ups are as high and dangerous as those produced by pumping failures. New subroutines were thus developed and included in the Closed Conduit Flow Transient Model developed by the Instituto de Ingenieria of the Universidad Nacional Autonoma de Mexico. This paper presents the mathematical model and its numerical solution using the Method of Characteristics and the Newton-Raphson Method. With the new modeling system it is possible to evaluate the pressure fluctuation time series due to start up at any pumping system. Using this new system a reliable explanation of bursts at the Rio Yaqui-Guaymas system could be set forth. [Spanish] Al disenar conducciones a presion, es comun que se preste especial atencion a los transitorios hidraulicos generados por paros de emergencia de los equipos de bombeo. En el acueducto rio Yaqui-Guaymas, Sonora, Mexico, los transitorios generados al poner en marcha los equipos de bombeo son tan importantes como los producidos por disparo de bombas. En el Instituto de Ingenieria de la UNAM, se desarrollo e implanto en su programa de simulacion de transitorios hidraulicos en tuberias a presion una subrutina para simular el arranque de equipos de bombeo. El modelo matematico esta formado por el conjunto de ecuaciones dinamica y de continuidad, asi como la condicion de frontera que describe el arranque de las bombas. Se reescriben las ecuaciones dinamica y de continuidad, con el metodo de las caracteristicas y se plantea un sistema de ecuaciones no lineales, el cual se resuelve con el metodo de las caracteristicas y se plantea un sistema de ecuaciones no lineales, el cual se resuelve con el metodo de newton-raphson. La simulacion del arranque de las bombas del acueducto en estudio, arroja valores de las cargas

New tools for subsurface imaging of 3D seismic Node data in hydrocarbon exploration =

Science.gov (United States)

Benazzouz, Omar

A aquisicao de dados sismicos de reflexao multicanal 3D/4D usando Ocean Bottom NODES de 4 componentes constitui atualmente um sector de importancia crescente no mercado da aquisicao de dados reflexao sismica marinha na industria petrolifera. Este tipo de dados permite obter imagens de sub-superficie de alta qualidade, com baixos niveis de ruido, banda larga, boa iluminacao azimutal, offsets longos, elevada resolucao e aquisicao de tanto ondas P como S. A aquisicao de dados e altamente repetitiva e portanto ideal para campanhas 4D. No entanto, existem diferencas significativas na geometria de aquisicao e amostragem do campo de ondas relativamente aos metodos convencionais com streamers rebocados a superficie, pelo que e necessario desenvolver de novas ferramentas para o processamento deste tipo de dados. Esta tese investiga tres aspectos do processamento de dados de OBSs/NODES ainda nao totalmente resolvidos de forma satisfatoria: a deriva aleatoria dos relogios internos, o posicionamento de precisao dos OBSs e a implementacao de algoritmos de migracao prestack 3D em profundidade eficientes para obtencao de imagens precisas de subsuperficie. Foram desenvolvidos novos procedimentos para resolver estas situacoes, que foram aplicados a dados sinteticos e a dados reais. Foi desenvolvido um novo metodo para deteccao e correccao de deriva aleatoria dos relogios internos, usando derivadas de ordem elevada. Foi ainda desenvolvido um novo metodo de posicionamento de precisao de OBSs usando multilateracao e foram criadas ferramentas de interpolacao/extrapolacao dos modelos de velocidades 3D de forma a cobrirem a extensao total area de aquisicao. Foram implementados algoritmos robustos de filtragem para preparar o campo de velocidades para o tracado de raios e minimizar os artefactos na migracao Krichhoff pre-stack 3D em profundidade. Os resultados obtidos mostram um melhoramento significativo em todas as situacoes analisadas. Foi desenvolvido o software necessario para o

Studies on magnetocaloric and magnetic coupling effects =

Science.gov (United States)

Amaral, Joao Cunha de Sequeira

O presente trabalho apresenta novas metodologias desenvolvidas para a analise das propriedades magneticas e magnetocaloricas de materiais, sustentadas em consideracoes teoricas a partir de modelos, nomeadamente a teoria de transicoes de fase de Landau, o modelo de campo medio molecular e a teoria de fenomeno critico. Sao propostos novos metodos de escala, permitindo a interpretacao de dados de magnetizacao de materiais numa perspectiva de campo medio molecular ou teoria de fenomeno critico. E apresentado um metodo de estimar a magnetizacao espontanea de um material ferromagnetico a partir de relacoes entropia/magnetizacao estabelecidas pelo modelo de campo medio molecular. A termodinamica das transicoes de fase magneticas de primeira ordem e estudada usando a teoria de Landau e de campo medio molecular (modelo de Bean-Rodbell), avaliando os efeitos de fenomenos fora de equilibrio e de condicoes de mistura de fase em estimativas do efeito magnetocalorico a partir de medidas magneticas. Efeitos de desordem, interpretados como uma distribuicao na interaccao magnetica entre ioes, estabelecem os efeitos de distribuicoes quimicas/estruturais nas propriedades magneticas e magnetocaloricas de materiais com transicoes de fase de segunda e de primeira ordem. O uso das metodologias apresentadas na interpretacao das propriedades magneticas de variados materiais ferromagneticos permitiu obter: 1) uma analise quantitativa da variacao de spin por iao Gadolinio devido a transicao estrutural do composto Gd5Si2Ge2, 2) a descricao da configuracao de cluster magnetico de ioes Mn na fase ferromagnetica em manganites da familia La-Sr e La-Ca, 3) a determinacao dos expoentes criticos β e δ do Niquel por metodos de escala, 4) a descricao do efeito da pressao nas propriedades magneticas e magnetocaloricas do composto LaFe11.5Si1.5 atraves do modelo de Bean-Rodbell, 5) uma estimativa da desordem em manganites ferromagneticas com transicoes de segunda e primeira ordem, 6) uma descricao de

Disintegration-Rate Determination by 4 {pi} Counting; Determination du taux de desintegrations par comptage 4 {pi}; Opredelenie skorosti raspada pri pomotsi 4 {pi} schetchikov; Determinacion de la velocidad de desintegracion por recuento 4 {pi}

Energy Technology Data Exchange (ETDEWEB)

Pate, Brian D [Chemistry Department, Washington University, St. Louis, MO (United States)

1960-06-15

The history of the development of the 4 {pi} counting method is reviewed. The unique properties of the 4 {pi} counter system are described and the criteria are specified which place disintegration rate measurements, made with the system, on an absolute basis. The types of radioactive decay process to which the method is applicable are outlined, together with the various errors to which a given measurement is liable. Departure of response probability from unity, absorption of radiation in the source-mounting system, and source self-absorption are discussed in detail. (author) [French] L'auteur fait l'historique des progres de la methode de comptage 4 {pi}. Il decrit les proprietes remarquables du dispositif de comptage 4 {pi} et precise les conditions dans lesquelles les mesures du taux de desintegration se font avec ce dispositif sur une base absolue. Il donne un apercu des types de processus de desintegration radioactive, ainsi que de diverses erreurs auxquelles est sujette une mesure donnee. Il examine en detail le cas ou la probabilite de reponse s'ecarte de l'unite, l'absorption des rayonnements dans le support de la source et l'autoabsorption de la source. (author) [Spanish] En la memoria el autor expone el desarrollo del metodo de recuento 4 {pi}. Describe las caracteristicas particulares de este metodo y explica las razones por las que las mediciones de la velocidad de desintegracion efectuadas segun ese procedimiento tienen un caracter absoluto. Se indican, asimismo, los tipos de procesos de desintegracion radiactiva a los que se puede aplicar el metodo, asi como los diferentes defectos de que puede adolecer una medicion determinada. Tambien se estudia detenidamente el caso en que la probabilidad de respuesta no es igual a la unidad, la absorcion de radiaciones en el soporte de la fuente y la autoabsorcion de la misma. (author) [Russian] Daetsya obzor istorii razvitiya metoda scheta s pomoshch'yu 4 {pi} schetchikov. Privoditsya opisanie unikal'nykh svojstv

Repercusión del ejercicio físico en la composición corporal y la capacidad aeróbica de adultos mayores con obesidad mediante tres modelos de intervención

OpenAIRE

Prieto, José Antonio; Valle, Miguel Del; Nistal, Paloma; Méndez, David; Abelairas-Gómez, Cristian; Barcala-Furelos, Roberto

2015-01-01

Objetivo: El objetivo de este estudio fue analizar la influencia del ejercicio aerobico en la composicion corporal y la capacidad aerobica de una muestra de adultos mayores, sedentarios y con indices de obesidad, mediante tres modelos diferentes de intervencion (recomendacion, prescripcion en el hogar y monitorizacion). Material y metodo: Participaron 76 adultos mayores con una edad media 67.1 +/- 1.2 anos, sedentarios, con un IMC > 30 kg/m² que se distribuyeron aleatoriamente en cuatro grupo...

Contributo di dati di gravità nella valutazione del vulcanismo CAMP in Africa Nord-Occidentale

OpenAIRE

Fabbri, Julius

2015-01-01

2013/2014 La domanda alla base di questa ricerca è stata se il metodo della gravimetria satellitare possa essere utilizzato per seguire le unità geologiche anche in luoghi difficilmente accessibili. L’obiettivo di questa ricerca è di verificare se le missioni satellitari di nuova generazione permettano di identificare la più grande delle province ignee della Terra (Bertrand et al., 2013), nota come CAMP (Central Atlantic Magmatic Province) in Africa nord-occidentale. Oltre alle motivazioni...

ANALIZA PODPORE KADROVSKIH PROCESOV S SISTEMOM SAP V PODJETJU AVTENTA.SI D.O.O.

OpenAIRE

Vehovec, David

2011-01-01

V okviru diplomskega dela so z metodo prenove poslovnih procesov predstavljeni procesi zaposlovanja in razporejanja, upravljanja kadrovskih podatkov in prenehanja delovnega razmerja v podjetju Avtenta.si d.o.o. Na podlagi popisanih procesov je narejena analiza njihove podprtosti s sistemom SAP in predlog prenove. Le-ta vključuje modele prenovljenih procesov in prilagoditev sistema SAP do nivoja delujočega prototipa. V teoretičnem delu so opisana področja prenove poslovnih procesov, upravl...

ESTUDIO COMPARATIVO DEL EFECTO DE ZHONGJI (RM3) MOXADO MAS PUNTOS REGULARES VS PUNTOS REGULARES EN PACIENTES CON NEUROPATIA DIABETICA -NO TIENE CARATULA-

OpenAIRE

LERMA GARCIA, HECTOR ALFONSO

2010-01-01

ANTECEDENTES: DESDE LA ANTIGUEDAD SE HA COMPROBADO LA EFECTIVIDAD DE LA ACUPUNTURA PARA EL TRATAMIENTO DEL DOLOR Y PARA LA DIABETES EN EL SER HUMANO. OBJETIVO: EL PRESENTE ESTUDIO TIENE COMO OBJETIVO ANALIZAR EL EFECTO DEL TRATAMIENTO DEL DOLOR Y ALTERACIONES SENSITIVAS EN PACIENTES CON NEUROPATIA DIABETICA. METODO: SE ESTUDIARON TREINTA PACIENTES CON UN DIAGNOSTICO DE NEUROPATIA DIABETICA LOS CUALES SE DIVIDIERON EN TRES GRUPOS A LOS CUALES SE LES APLICO EN EL GRUPO 1 ZHONG...

Matriz para ingenieria de tejido oseo: modificacion superficial con zinc Estudio preliminar

OpenAIRE

Martinez, Cristian; Olmedo, Daniel; Ozols, Andres

2013-01-01

El objetivo del presente trabajo es desarrollar un metodo de sintesis de matrices para ingenieria de tejidos, capaces de acelerar los procesos reparativos y disminuir el riesgo de infeccion, destinadas a cirugias reconstructivas que involucren el tejido oseo. A este fin se emplea la fase mineral de hueso bovino, la hidroxiapatita, conservando su estructura tridimensional. Esta se obtiene a partir de un proceso de lavado quimico, seguido de un proceso termico que elimina todos los componentes ...

Aceite de oliva virgen extra del Somontano: evaluación de las modificaciones físico- químicas tras la fritura doméstica de patatas prefritas congeladas

Directory of Open Access Journals (Sweden)

Oria, R.

2008-03-01

Full Text Available The behavior of Somontano extra virgin olive oil (obtained from Empeltre and Arbequina olive varieties in the domestic deep frying of prefried frozen potatoes was studied by submitting the olive oil to successive frying cycles. After different frying cycles physico-chemical modifications were monitored through the determination of several chemical (iodine value, total phenols content and physical parameters (viscosity and ultraviolet spectra. An increase in viscosity and a decrease in iodine value, total phenol content and an increase in absorbance at 235, 269 y 280 nm were observed. In general, Somontano olive oil was revealed appropriate for domestic frying because of the high number of frying cycles permitted before reaching the polar compound limit established by Spanish legislation.Se estudió el comportamiento del aceite de oliva virgen extra del Somontano (obtenido a partir de aceitunas de las variedades Empeltre y Arbequina en la fritura doméstica de patatas prefritas congeladas por inmersión, sometiendo al aceite a ciclos sucesivos de fritura. Tras los distintos ciclos se monitorizaron las modificaciones físico-químicas mediante la determinación de diversos parámetros químicos (indice de yodo, contenido en fenoles totales y físicos (viscosidad y espectros ultravioleta. Se observó un aumento de la viscosidad, y una disminución en el índice de yodo, en el contenido de fenoles, así como el aumento de la absorbancia en el ultravioleta a 235, 269 y 280 nm. Sin embargo, el aceite del Somontano se reveló como muy adecuado para la fritura doméstica por el elevado número de ciclos de fritura (66 que se pudieron realizar sin sobrepasar el límite de compuestos polares establecido por la legislación.

Estrés oxidativo, alimentación y suplementación antioxidante en patología ocular: historia breve y visión futura Oxidative stress, feeding and antioxidant supplementation in ocular pathology: brief history and future vision

Directory of Open Access Journals (Sweden)

Alfredo Gutiérrez Maydata

2007-12-01

Full Text Available Los ojos están en riesgo particular de daño oxidativo debido a su alta exposición al oxígeno, gran cantidad de ácidos grasos oxidables en la retina y su también alta exposición a la luz, los contaminantes ambientales y los rayos ultravioleta. En el presente trabajo se discuten las evidencias encontradas del posible papel del daño oxidativo en la patogenia de diversos trastornos oculares (glaucoma, cataratas, retinopatía diabética, degeneración macular; y de la dieta y la suplementación con antioxidantes en su prevención y tratamiento. De momento las actuales recomendaciones se inclinan a la importancia de una dieta variada, alta en frutas y vegetales, no fumar, evitar el exceso de exposición al sol y a las radiaciones ultravioletas y en los pacientes diabéticos mantener un estricto control de la glicemia como la estrategia antioxidante más efectiva, mientras se investigan los beneficios probados de suplementos antioxidantes.The eyes are at risk of suffering oxidative damage due to their high exposure to oxygen, a great deal of fatty acids in the retina and also to light, environmental pollutants and ultraviolet rays. The present paper discussed the evidence found about the possible role of oxidative damage in the pathogenesis of several eye diseases (glaucoma, cataract, diabetic retinopathy, macular degeneration and the role of diet and antioxidant supplements in the prevention and treatment of such diseases. At present, the current recommendations cover the importance of a varied diet with high contents of fruits and vegetables, non-smoking, avoiding excessive exposure to the sun and ultraviolet radiations and a stict control of glycemic levels in diabetic patients as the most effective antioxidant strategy. The proven benefits of antioxidant supplements are being researched at present.

Pathology of the vestibulocochlear nerve

Energy Technology Data Exchange (ETDEWEB)

De Foer, Bert [Department of Radiology, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium)], E-mail: bert.defoer@GZA.be; Kenis, Christoph [Department of Radiology, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium)], E-mail: christophkenis@hotmail.com; Van Melkebeke, Deborah [Department of Neurology, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium)], E-mail: Deborah.vanmelkebeke@Ugent.be; Vercruysse, Jean-Philippe [University Department of ENT, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium)], E-mail: jphver@yahoo.com; Somers, Thomas [University Department of ENT, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium)], E-mail: Thomas.somers@GZA.be; Pouillon, Marc [Department of Radiology, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium)], E-mail: marc.pouillon@GZA.be; Offeciers, Erwin [University Department of ENT, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium)], E-mail: Erwin.offeciers@GZA.be; Casselman, Jan W. [Department of Radiology, AZ Sint-Jan AV Hospital, Ruddershove 10, Bruges (Belgium); Consultant Radiologist, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium); Academic Consultent, University of Ghent (Belgium)], E-mail: jan.casselman@azbrugge.be

2010-05-15

There is a large scala of pathology affecting the vestibulocochlear nerve. Magnetic resonance imaging is the method of choice for the investigation of pathology of the vestibulocochlear nerve. Congenital pathology mainly consists of agenesis or hypoplasia of the vestibulocochlear nerve. Tumoral pathology affecting the vestibulocochlear nerve is most frequently located in the internal auditory canal or cerebellopontine angle. Schwannoma of the vestibulocochlear nerve is the most frequently found tumoral lesion followed by meningeoma, arachnoid cyst and epidermoid cyst. The most frequently encountered pathologies as well as some more rare entities are discussed in this chapter.

Pathology of the vestibulocochlear nerve

International Nuclear Information System (INIS)

De Foer, Bert; Kenis, Christoph; Van Melkebeke, Deborah; Vercruysse, Jean-Philippe; Somers, Thomas; Pouillon, Marc; Offeciers, Erwin; Casselman, Jan W.

2010-01-01

There is a large scala of pathology affecting the vestibulocochlear nerve. Magnetic resonance imaging is the method of choice for the investigation of pathology of the vestibulocochlear nerve. Congenital pathology mainly consists of agenesis or hypoplasia of the vestibulocochlear nerve. Tumoral pathology affecting the vestibulocochlear nerve is most frequently located in the internal auditory canal or cerebellopontine angle. Schwannoma of the vestibulocochlear nerve is the most frequently found tumoral lesion followed by meningeoma, arachnoid cyst and epidermoid cyst. The most frequently encountered pathologies as well as some more rare entities are discussed in this chapter.

Caracterización clinicopatológica de los tumores malignos palpebrales

OpenAIRE

Ramírez García, Lázara Kenia; Ortiz Ramos, Datia Liset; Gómez Cabrera, Clara Gisela; Vigoa Aranguren, Lázaro; Rojas Rondón, Irene; Abreu Perdomo, Franklyn Alain

2014-01-01

Objetivos: describir las características clinicopatológicas de los tumores malignos palpebrales. Métodos: estudio descriptivo y retrospectivo de pacientes con diagnóstico histopatológico de carcinoma basocelular, epidermoide y adenocarcinoma de glándulas sebáceas, atendidos en el Servicio de Oculoplastia del Instituto Cubano de Oftalmología, de enero de 2005 a diciembre de 2010. Se incluyó un total de 109 pacientes; se analizó la edad, el sexo, el color de la piel, las formas clínicas, la loc...

Radiologic evaluation of the myelomeningocele patient

International Nuclear Information System (INIS)

Byrd, S.E.; Radkowski, M.A.; McLone, D.G.; Storrs, B.B.

1988-01-01

The only radiologic procedure that is useful in the newborn with a fresh myelomeningocele is US or CT of the head to evaluate ventricular size. The imaging procedures become extremely important in the evaluation of the postoperative patient with myelomeningocele. US and/or CT is used to evaluate for hydrocephalus. MR is used to evaluate the spinal axis to determine the position of the cervicomedullary kink, hydromyelia, arachnoid cyst, inclusion epidermoids, and tethering of the spinal cord. US and myelography with CT are needed in subtle cases of tethering, diastematomyelia, arachnoid cyst, and severe scoliosis

Dental management of the complications of radio and chemotherapy in oral cancer

OpenAIRE

Caribé Gomes, Fabiana; Chimenos Küstner, Eduardo; López López, José, 1958-; Finestres Zubeldia, Fernando; Guix Melcior, Benjamín

2003-01-01

El cáncer más comúnmente encontrado en la cavidad oral es el carcinoma de células escamosas o epidermoide, que constituye, aproximadamente, el 5% de todas las neoplasias. Desafortunadamente, la gran mayoría de estos tumores son diagnosticados en estadios que exigen la instauración de tratamientos quirúrgicos, radioterapia y quimioterapia. La radioterapia se presenta como una importante opción en la terapéutica de los tumores bucales, pudiendo ser empleada sola o en combinación con la cirugía ...

Radiation Treatment of Esophageal Cancer

International Nuclear Information System (INIS)

Oh, W. Y.; Suh, C. O.; Kim, G. E.

1985-01-01

63 patients who were irradiated with a goal of long term control among 101 patients with esophageal cancer seen during an 11 years period between Jan, 1970 and Dec, 1980 at Yonsei Cancer Center in Seoul, Korea have retrospectively analysed. 52(82.5%) among the 63 patients were confirmed to have epidermoid carcinoma in the histology. The actuarial 3 and 5 years survival rates of 17 cased of T1, esophageal cancer were 24.7% and 20.8%. Statistically, there was no significant difference in survival rate according to tumor location (p>0.05)

Perichiasmatic granuloma occuring after radical mastoidectomy: MR findings

Energy Technology Data Exchange (ETDEWEB)

Djouhri, H.; Marsot-Dupuch, K.; Tubiana, J.M. [Hopital Saint-Antoine, Service de Radiologie, Paris (France); Joutel, A. [Hopital Saint-Antoine, Service de Neurologie, Paris (France); Kujas, M. [Hopital la Pitie Salpetriere, Laboratoire d`Histologie-Embryologie, Paris (France); Brette, M.D. [Hopital Saint-Louis, Service d`ORL, Paris (France); Artuis, F. [Hopital la Pitie Salpetriere, Service de Neurochirurgie de la Pitie, 83 boulevard de l`Hopital, F-75013 Paris (France)

1998-03-01

A case of chronic chemical meningitis occurring after a radical mastoidectomy is reported. Imaging and surgical findings were suggestive of a dissemination of cholesteatoma debris within the subarachnoid spaces. Chemical meningitis has been described in epidermoid and dermoid cyst rupture. This report illustrates that clinicians should be aware of this possible complication. Skull base imaging is mandatory before considering the diagnosis of idiopathic meningitis. Only treatment of the abnormal communication between cerebrospinal fluid and middle ear may eradicate the origin of this rare meningitis. (orig.) With 6 figs., 15 refs.

Penifupyrone, a new cytotoxic funicone derivative from the endophytic fungus Penicillium sp. HSZ-43.

Science.gov (United States)

Chen, Ming-Jun; Fu, Yang-Wu; Zhou, Qun-Ying

2014-01-01

Penifupyrone (1), a new funicone derivative, has been isolated from the endophytic fungus Penicillium sp. HSZ-43, along with three known analogues, funicone (2), deoxyfunicone (3) and 3-O-methylfunicone (4). These structures were identified by using spectroscopic methods, including UV, MS, 1D and 2D NMR experiments. The structure of 1 was confirmed by single-crystal X-ray diffraction analysis. All the isolated compounds were evaluated for cytotoxicity against human oral epidermoid carcinoma KB cells, and compound 1 exhibited moderate cytotoxic activity with IC50 value of 4.7 μM.

Carboplatin: the clinical spectrum to date.

Science.gov (United States)

Canetta, R; Rozencweig, M; Carter, S K

1985-09-01

The existing literature data base on carboplatin updated to June, 1985 has been reviewed. The compound seems to retain the same spectrum of activity as cisplatin, and a definite set of efficacy data is available for ovarian cancer of epithelial origin, small cell carcinoma of the lung and epidermoid carcinoma of the head and neck. A yet unpublished toxicity data base on carboplatin suggests that the compound has an improved therapeutic index over the parent compound, cisplatin, and that it does not seem inferior to another platinum coordination compound currently in clinical trials, iproplatin.

Computed tomographic features of orbital lesions

International Nuclear Information System (INIS)

Azevedo, C.M. de; Hoch, H.; Azevedo, M. de L.

1990-01-01

The purpose of this m anuscript is to present the use of CT in the evaluation of 42 cases of orbital lesions studied at the National Institute of Cancer in an one year and half period. Correlation with clinical and pathological data was performed and the results compared with those of the literature. Four cases of rare lesions are shown: alveolar soft tissue sarcoma, giant cell tumor and hematogenic metastatic deposits of a clear cell sarcoma and epidermoid carcinoma. The value of CT in the evaluation of all orbital masses is emphasized. (author) [pt

Impacto de un programa de foto-educación en los conocimientos y hábitos de una población escolar.

OpenAIRE

Adriana R. Cruz; Ximena Hormaza; Juliana Díaz; Andrés Vidal; Janeth Villanueva; Giovanna Osorio; Marisol Rebolledo; Luis Fernando Cárdenas

2005-01-01

Introducción. Colombia está expuesta todo el año a altos índices de radiación ultravioleta. Aunque aún no se cuenta con estadísticas precisas del cáncer cutáneo, se sabe que este problema es una causa frecuente de consulta, presentándose cada día en personas más jóvenes. Por esta razón, se realizó un trabajo de foto-educación en colegios de estrato socioeconómico 1 a 4 en Cali. Objetivo. Determinar el impacto de la foto-educación en los conocimientos y prácticas de fotoprotección en una pobla...

El cancer de piel y el sol: la protección como alternativa

OpenAIRE

Ochoa, María Teresa; Fundación Valle de Lili; Rueda Plata, Ricardo A.

1996-01-01

¿Qué es la radiación ultravioleta?/¿Qué factores afectan la cantidad de radiación UV que alcanza la tierra?/¿Qué efectos produce el sol sobre la piel? Quemadura solar aguda/Bronceamiento/Envejecimiento/Cáncer/¿Existen varios tipos de cáncer de piel?/¿Cómo se sospecha el melanoma de piel?/¿Cómo se diagnostica el cáncer de piel?/¿Cómo trata el cáncer de piel?/¿Cómo se puede detectar a tiempo?/¿Cómo se puede proteger del sol y no correr riesgos?/¿Qué es un protector solar?/¿Cómo elegir un buen p...

Susceptibilities to carbapenems and presence of cphA gene on food-borne Aeromonas

Directory of Open Access Journals (Sweden)

Bibiana María Martín Talavera

2006-07-01

Full Text Available The purpose of this study was to determine the susceptibilities of food-borne Aeromonas to carbapenems, as well as to investigate the presence of a metallo carbapenemase-encoding gene, named cphA. Minimum Inhibitory Concentration (MIC was determined following NCCLS standards. All the tested microorganisms were susceptible to imipenem, meropenem and biapenem. However, a strong inoculum size effect on carbapenem MICs was observed for most of the strains. Six strains, out of seven, showed the presence of metallo--beta-lactamases but cphA gene was detected in only two strains of A. veronii bv. sobria.O objetivo deste estudo foi determinar a suscetibilidade de aeromonas de origem alimentar a carbapenems bem como investigar a presença de um gene codificante de metalocarbapenemase, denominado "cph A". A suscetibilidade in vitro foi determinada pelo metodo de diluição em agar. Todas as cepas foram suscetíveis a Imipenem, Meropenem e Biapenem. Porém foi observado um forte efeito de tamanho do inóculo sobre as CIM das carbapenems na maioria das cepas. A detecção de metalo-beta-lactamase foi realizada pelo metodo lodometrico. Seis cepas das sete testadas demostraron a presença da enzima. A presença do gene cphA foi determinada por PCR e foi detectada em duas cepas de A veronii bv. sobria.

Modos de produccion cientifica: Culturas y metodologias de investigacion en la Universidad de Cadiz

Science.gov (United States)

Gonzalez Ramos, Ana M.

2004-12-01

Este trabajo de investigacion supone un modelo teorico de caracter aplicado, que proporciona la oportunidad de evaluar la produccion cientifica de los investigadores. Se encuadra dentro de la tradiccion de la estadistica aplicada y la sociologia del conocimiento. Atiende especialmente a dos conjuntos de temas de interes, por una parte, las caracteristicas principales que determinan el nivel y tipo de produccion academica producida por las unidades de investigacion y por los propios investigadores; por otra, la utilizacion que se hace de los metodos y tecnicas de investigacion puesto que de ello tambien depende el modo de produccion cientifica. Los puntos novedosos de esta tesis son: la medicion cuantitativa del objeto de estudio, la suma de los productos y las condiciones externas a la produccion del conocimiento mas otros elementos internos como las caracteristicas de los investigadores y la metodologia utilizada para desarrollar sus trabajos; y, finalmente, el uso de las nuevas tecnologias. El aprovechamiento de los recursos estadisticos y las fuentes de informacion secundarias se complementan con el diseno propio de una encuesta donde se implementa las caracteristicas descritas en un capitulo anterior sobre los metodos cientificos mas idoneos descritos en los principales manuales y articulos cientificos desde distintas disciplinas de conocimiento. Dicha encuesta ha sido desarrollada como un programa propio y en base a los mas innovadores usos de la tecnologia en la metodologia de encuestas.

Determination of Radiotracer Stability of Tritium-Labelled Compounds in Biological Studies; Determination de la Stabilite des Composes Trities Employes comme Indicateurs en Biologie; 041e 043f 0440 0435 0434 0414 043b ; Determinacion de la Estabilidad de los Compuestos Tritiados en los Estudios Biologicos Mediante Indicadores

Energy Technology Data Exchange (ETDEWEB)

Okita, G. T.; Spratt, J. L. [Argonne Cancer Research Hospital and Department of Pharmacology, University of Chicago, Chicago, IL (United States)

1962-02-15

compuestos marcados hasta lograr una actividad especifica constante no excluye la posibilidad de que en los organismos vivos se produzca un intercambio entre atomos de tritio y de hidrogeno. La estabilidad radiotrazadora puede demostrarse mediante diversos metodos, una vez que se haya efectuado una purificacion radioquimica meticulosa de la sustancia marcada. En la memoria se describen tres metodos diferentes utilizados para determinar la estabilidad radiotrazadora de los compuestos de tritio. Uno de ellos consiste en comparar el periodo biologico de un compuesto de {sup 3}H con el de un compuesto similar marcado con {sup 14}C. Este metodo es aplicable especialmente a las sustancias endogenas que sufren una dilucion isotopica al ser administradas a los animales. La estabilidad de los compuestos exogenos puede comprobarse mediante un segundo metodo, con arreglo al cual basta demostrar que no se produce disminucion de la actividad especifica cuando la sustancia marcada se aisla de nuevo de las muestras biologicas. Un tercer metodo, mas rapido que el primero, y aplicable tanto a las sustancias endogenas como exogenas, consiste en determinar la razon isotopica {sup 3}H/{sup 14}C en una mezcla del mismo compuesto marcado con ambos isotopos. La constancia de las razones isotopicas antes de administrar la sustancia doblemente marcada y despues de aislarla de nuevo de organos o excreta constituye una prueba de su estabilidad radiotrazadora. Este metodo es aplicable especialmente en los casos en que el aislamiento de vestigios de sustancia exige el empleo de un portador inactivo. En la memoria se presentan datos relativos al empleo de estos metodos para la comprobacion de la estabilidad radiotrazadora, con especial referencia al colesterol, la morfina y la digitoxina marcadas, como ejemplos de los tres metodos mencionados. (author) [Russian] Rasprostranivsheesja za poslednee vremja v biologicheskih issledovanijah shirokoe primenenie mechen- nyh tritiem soedinenij vyzyvaet

USO DA SISTEMATIZAÇÃO DA ASSISTÊNCIA DE ENFERMAGEM (SAE: UMA FERRAMENTA PARA REALIZAÇÃO DA AUDITORIA DE QUALIDADE

Directory of Open Access Journals (Sweden)

Maria Izelta da Silva Santos

2013-04-01

Full Text Available Realizar uma revisao bibliografica acerca da Sistematização da Assistencia de Enfermagem (SAE como instrumento para auditoria de qualidade. Metodos: Foram revisados 12 artigos cientificos sobre auditoria e 10 artigos sobre SAE, bem como dois livros sobre os assuntos abordados. Esta revisao e de carater descritivo. Resultados: Por meio da pesquisa, tornou-se evidente a correlação da SAE com a auditoria. A SAE bem implementada pode contribuir para uma auditoria de qualidade.

Uporaba hipnoze pri preiskovanju kaznivih dejanj

OpenAIRE

Radić, Janja

2016-01-01

V svojem diplomskem delu predstavljam tehniko hipnoze kot metodo za izboljšanje spomina pri pričah in žrtvah kaznivih dejanj. Posvetim se pojmovanju in uporabi hipnoze skozi zgodovino, nato pa podam še njeno definicijo in tehnike. Poleg načina uporabe hipnoze pri preiskovanju kaznivih dejanj, predstavim tudi njene prednosti in slabosti, opišem potek hipnotiziranja ter vlogo in funkcijo hipnotizerja. V zadnjih dveh poglavjih pojasnim vpliv spomina na hipnotične informacije ter predstavim pravn...

Efecto de la fuente nitrogenada sobre la capacidad de degradacio?n del petro?leo diesel 2 por Pseudomonas sp.

OpenAIRE

Otiniano-Garci?a, Ne?lida Milly

2013-01-01

Gran parte del desarrollo creciente de la sociedad moderna y contempora?nea se fundamenta en la explotacio?n de petro?leo, el aumento de la demanda de este hidrocarburo, implica un alto riesgo de derrames accidentales que pueden ser minimizados, mas no totalmente eliminados. La preocupacio?n por el medio ambiente aumento? despue?s de los grandes derrames que causaron graves dan?os en el ecosistema; en consecuencia, se desa- rrollaron te?cnicas que incluyen me?todos fi?sicos, qui?micos y biolo...

FACTORES INDIVIDUALES, FAMILIARES Y SOCIALES ASOCIADOS AL EMBARAZO EN ADOLESCENTES EN EL CENTRO DE SALUD CARLOS SHOWING FERRARI 2014 - 2015

OpenAIRE

Luyo Marcellini, Delci Fiorella

2017-01-01

OBJETIVO: Determinar los factores individuales, familiares y sociales asociados al embarazo en adolescentes en el Centro de Salud Carlos Showing Ferrari del periodo de enero del 2014 a diciembre del 2015. METODOS Y TECNICA: El estudio fue observacional, longitudinal, retrospectivo. Con un diseño caso y control. La técnica utilizada fue el fichaje en base a la recolección de datos de fuentes secundarias. RESULTADOS: Dentro de los Factores individuales de riesgo asociados al embarazo en ...

Caracterización de la infección de las vías urinarias en mujeres embarazadas atendidas en una entidad de primer nivel de atención (Manizales, Colombia) 2006-2010

OpenAIRE

Arroyave, Valentina; Cardona, Andrés Felipe; Castaño Castrillón, José Jaime; Giraldo, Viviana; Jaramillo, Mariana; Moncada, Norma Cecilia; Aicardo Ortiz, Ernesto; Villegas Arenas, Oscar Alberto

2010-01-01

ANTECEDENTES: Las infecciones del tracto urinario son las complicaciones más frecuentes del embarazo. Ocasionan una seria morbilidad materna y perinatal (parto pretérmino, peso bajo al nacer y ruptura prematura de membranas).MATERIALES Y METODOS: Estudio de corte transversal, con muestra de 1429 historias de gestantes que asistieron a controles prenatales y al parto en ASSBASALUD E. S. E. Manizales, Colombia. Para realizar este estu-dio se diseñó un instrumento, con las variables escogidas, p...

Evolution operators and transformation of states under uniform and an/or elastic forces into free particle states

Energy Technology Data Exchange (ETDEWEB)

Dattoli, G.; Torre, A. [ENEA, Centro Ricerche Frascati, Rome (Italy). Dipt. Innovazione

1999-07-01

In this paper are exploited the techniques, associated with the evolution operator method, to prove the existence of a one-to one correspondence between the wave function of a free particle and those of a particle ruled by a quadratic Hamiltonian. [Italian] Le tecniche associate al metodo dell'operatore di evoluzione vengono utilizzate per dimostrare l'esistenza di una corrispondenza biunivoca tra la funzione d'onda di una particella libera e quella di una particella soggetta ad un potenziale armonico.

Raziskava stališč o leseni gradnji v Sloveniji v letu 2006

OpenAIRE

Kitek Kuzman, Manja; Hrovatin, Jasna

2007-01-01

Lesena gradnja predstavlja na področju stanovanjskih stavb v Sloveniji le majhen delež celotne gradnje. Želeli smo ugotoviti, kaj je vzrok tako majhnegadeleža lesene gradnje v Sloveniji. Z javnomnenjsko raziskavo "Slovensko javno mnenje o leseni gradnji" smo anketirance spraševali o poznavanju lesene gradnje in njenih prednostih. Zbiranje podatkov je bilo opravljeno z metodo CATI. Ugotovljeno je bilo, da javnost ni dovolj seznanjenas prednostmi lesene gradnje.Večina vprašanih, ki živi v indiv...

Dielektrične lastnosti vodnih raztopin nekaterih mono- in polisaharidov

OpenAIRE

Gubenšek, Špela

2017-01-01

V magistrskem delu smo raztopinam različnih saharidov določali dielektrične lastnosti. Analizirali smo vodne raztopine glukoze, fruktoze, inulina, dekstrina, maltodekstrina, oligofruktoze in glukozno-fruktoznega sirupa. Saharide smo okarakterizirali tako, da smo določili njihove reducirajoče lastnosti in v glukozno-fruktoznem sirupu delež fruktoze. Za določanje dielektrične konstante v območju frekvenc izmenične napetosti med 20 kHz in 2 MHz smo uporabili kapacitivno metodo in LCR merilnik. ...

Research and Development Activities in Italy in the Field of Aerospace Structures and Materials,

Science.gov (United States)

1979-03-01

Aerotecnica, Missili e Spazio ” . An extensive historical and critical analysis of such long lasting research cannot be given here; the more recent results are...in the AGARD SMP Program on “ Critically Loaded Hole Technology ” carrying Out Falstaff spectrum fatigue tests on behalf of Italy ,~~ 7. The Un... Metodo degli Elementi Fi— niti — Prestampa n . 5 , IV °Congresso Nazionale A . I . D . A . A . ,M i l a — no ,1977 . 20. Cella Analisi di problein i

Theory of the Sagnac's interferometer of low birefringence and twist fiber; Teoria del interferometro de Sagnac de fibra de baja birrefrigencia y torcida

Energy Technology Data Exchange (ETDEWEB)

Estudillo-Ayala, J. M.; Kuzin, E. A.; Ibarra-Escamilla, B. [Instituto Nacional de Astrofisica, Optica y Electronica, Puebla (Mexico); Rojas-Laguna, R. [Universidad de Guanajuato, Guanajuato (Mexico)

2001-06-01

The fibre Sagnac interferometer of low birefringence and twist in the lineal region is examined numerically, a method is shown to measure the birefringence in the fibers and rotation of the axes inside of the interferometer fibre loop. [Spanish] El interferometro de Sagnac de fibra de baja birrefrigencia y torcida en la region lineal es numericamente examinado, se muestra un metodo para medir la birrefrigencia en las fibras y rotacion de los ejes dentro de la fibra del lazo del interferometro.

Pulsed and Static Neutron Measurements in Light-Water and Heavy-Water Exponentials; Mesures par les Methodes Pulsee et Statique dans les Ensembles Exponentiels a Eau Legere et a Eau Lourde; Izmerenie impul'snykh i staticheskikh nejtronov v ehksponentsial'nykh ustanovkakh s obychnoj i tyazheloj vodoj; Mediciones por los Metodos Pulsados y Estaticos en Conjuntos Exponenciales de Agua Ligera y Agua Pesada

Energy Technology Data Exchange (ETDEWEB)

Parkinson, T. F.; Perez, R. B.; Fry, D. N.; Hartley, R. H.; Smith, S. P.D.; Diaz, N. J. [University of Florida, Gainesville, FL (United States)

1964-04-15

etant le laplacien geometrique du systeme equivalent sans reflecteur avec gain reflecteur. Modele C: On imagine un systeme sans reflecteur a deux groupes avec gain reflecteur. En comparant les constantes de decroissance obtenues par calcul et par voie experimentale, on constate que seul le modele A assure une concordance satisfaisante. On peut en tirer les conclusions ci-apres: 1. La presence du reflecteur a una grande influence sur la physique du systeme puise. L'hypothese selon laquelle on admet un gain reflecteur n'est pas toujours valable. 2. La valeur de la constante de decroissance {lambda} depend etroitement de la valeur admise pour la probabilite d'absence de fuite de neutrons rapides. Les experiences indiquent que la methode des neutrons puises permet de determiner k{sub {infinity}} pour des ensembles heterogenes de petites dimensions. Des travaux sont en cours sur des barres d'uranium creuses qui permettent de simuler l'emploi de fluides de refroidissement organiques. (author) [Spanish] Desde hace tiempo se recurre a experimentos exponenciales para determinar el laplaciano material de un medio multiplicador. En fecha mas reciente se ha comenzado a utilizar la tecnica de los neutrones pulsados para medir los valores propios del tiempo, {lambda}, de los que puede deducirse k{sub {infinity}}. Este ultimo metodo presenta la ventaja de que permite el empleo de reticulados mas pequefios que el metodo exponencial estatico. Sin embargo, para establecer la validez del metodo pulsado, es preciso comparar sus resultados con los obtenidos mediante los metodo estaticos. Los autores han efectuado estas mediciones en sistemas con y sin reflector, utilizando H{sub 2}O y D{sub 2}O en calidad de moderador; en los experimentos emplearon un tanque de 1 m de diametro. La correlacion entre las constantes de decrecimiento medidas y los parametros pertinentes del sistema se efectuo empleando un modelo teorico modificado de un solo grupo (denominado modelo A). El valor de {lambda} se

Il metodo di Aristarco à solo un modello?

Science.gov (United States)

Sigismondi, Costantino; Agolini, Giorgia

2017-06-01

The method of Aristarchus of Samo to measure the distance Earth-Sun is well known as the first step in the cosmological distance ladder. Our task is to understand if it is worth to repeat it also experimentally, with positive conclusions, especially with respect to the experimental design.

Adaptyvaus 2d pozicionavimo metodo autonominiam robotui tyrimas

OpenAIRE

Senvaitis, Vytautas

2016-01-01

Overview SLAM algorithm, laser distance scanner working principle, EKF and UKF filters in analytical part. EKF mathematical models are implemented for autonomous robot whit two-wheel drive and for laser distance scanner. EKF and UKF filters are compared. 2D robot positioning with EKF filter are modeled and simulated in MATALB and STM32 microcontroller with DSP library. MATLAB and STM32 are compared in speed test. Analyzing EKF filter working. Design and construct autonomous robot experimental...

Sensitivity of winter phytoplankton communities from Andean lakes to artificial ultraviolet-B radiation Sensibilidad de comunidades fitoplanctónicas invernales de lagos andinos a la radiación ultravioleta-B artificial

Directory of Open Access Journals (Sweden)

E. WALTER HELBLING

2001-06-01

Andinos con el objetivo de determinar la sensibilidad de comunidades fitoplanctónicas invernales a la radiación ultravioleta-B (UV-B, 280-320 nm. Los lagos estudiados, Moreno, El Trébol, Nahuel Huapi, Gutiérrez y Morenito, están ubicados la región Patagónica (41° S, 71° W, 800 m de altitud y tienen coeficientes de atenuación variables entre 0,36 m-1 (Lago Moreno y 2,8 m-1 (Lago Morenito. Las muestras se inocularon con carbono marcado (NaH14CO3 y se incubaron en una cámara iluminada (UV-B = 0,35 W m-2, UV-A [320-400 nm] = 1,1 W m-2, y PAR [400-700 nm] = 10,8 W m-2 a 10° C. El fitoplancton se expuso a PAR (radiación fotosintéticamente activa + radiación UV (tubos de cuarzo, y a PAR + UV-A (tubos de cuarzo recubiertos con Mylar-D. La duración total de los experimentos fue de 4 h y se retiraron dos muestras de cada tratamiento cada 1 h. En los Lagos Moreno, El Trébol, Nahuel Huapi y Gutiérrez la inhibición fotosintética aumentó en forma linear con la dosis de UV-B, mientras que en el Lago Morenito esta relación fue débil. Después de recibir una dosis de 1,25 kJ m-2 (UV-B, el fitoplancton del Lago Morenito tuvo la mayor inhibición fotosintética acumulada (44 %, mientras que en los Lagos Moreno, Trébol, Nahuel Huapi y Gutiérrez la inhibición fue de 22, 11, 5 y 1 %, respectivamente. Sin embargo, al final de la incubación, y luego de recibir una dosis de 5 kJ m-2, el fitoplancton más inhibido fue aquel del Lago Moreno (70 %, y el más resistente aquel del Lago Gutiérrez (27 %. La cinética de inhibición fue distinta para cada lago, registrándose una mayor velocidad en los lagos más transparentes y con mayor proporción de células grandes. Los resultados sugieren que, ante un aumento de UV-B (e.g., producto de una disminución de ozono estratosférico, el microplancton de lagos más claros será el más afectado mientras que el pico- y nanoplancton de lagos menos transparentes será el más resistente

Carcinoma sebáceo palpebral: Presentación de un caso Palpeebral sebaceous carcinoma: A case report

Directory of Open Access Journals (Sweden)

María Cáceres Toledo

1999-06-01

Full Text Available Se presenta a un paciente de 26 años de edad, con diagnóstico clínico de chalación gigante del párpado inferior del ojo derecho de 6 meses de evolución, con un gran componente inflamatorio y bordes ulcerados que no había respondido a la terapéutica médica ni quirúrgica. El resultado de la biopsia tomada de este lesión fue, carcinoma epidermoide infiltrante, por lo que decidimos hacer la cirugía con margen oncológico, que requirió de un colgajo libre del párpado superior con fines estéticos y funcionales. El estudio histológico de la tumoración evidenció un carcinoma sebáceo. La evolución posoperatoria de este paciente, al año de operado, ha sido satisfactoriaA 26-year-old patient wich clinical diagnosis of giant chalazi on of the lower eyelid of the right eye with 6 months of evolution and with a great inflamatory component and ulcerated edges that had not responded to mechical and surgical therapeutics is presented. The result of the biopsy was infiltrating epidermoid carcinoma, so it was decided to perform surgery with oncological margin that required a free flap of the upper eyelid with aesthetic functional ends. The histological study of the tumor proved the existance of a sebaceous carcinoma. The posoperative evolution of the patient after a year has been satisfactory

Low-density lipoprotein as a potential vehicle for chemotherapeutic agents and radionucleotides in the management of gynecologic neoplasms

International Nuclear Information System (INIS)

Gal, D.; Ohashi, M.; MacDonald, P.C.; Buchsbaum, H.J.; Simpson, E.R.

1981-01-01

Cholesterol metabolism was studied in cells from two established gynecologic cancer cell lines which were maintained in monolayer cultures. The cell lines were derived and established from poorly differentiated epidermoid cervical carcinoma and endometrial adenocarcinoma. The specific activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol de novo synthesis, in AC-258 cells was three times higher than that found in EC-50 cells. However, epidermoid cervical cancer cells metabolized low-density lipoprotein, the major transport vehicle for cholesterol in plasma, at a very high rate. This rate is fifteen times greater than the rate observed in fetal adrenal tissue and fifty times greater than the rate observed in nonneoplastic gynecologic tissue, each in organ culture. Both cancer cells in monolayer culture were shown to have specific receptors for LDL. These cancer cells demonstrate no defect in LDL metabolism, and lysosomal degradation of LDL was blocked by chloroquine. From the results of studies of specific binding of LDL in tissues obtained from nude mice it was demonstrated that membrane fractions prepared from EC-50 cells, after propagation in the mice, contained fifteen to thirty times more specific binding capacity for [125I]iodo-LDL than vital organs of the mouse, such as the liver, heart, lung, kidney, or brain. The results of these studies are suggestive that certain tumor cells might have a higher affinity for LDL than normal tissues and cytotoxic drugs or radionucleotides ligated to the LDL macromolecule may be utilized for the specific delivery of these agents

Evaluating in-home water purification methods for communities in Texas on the border with Mexico Evaluación de métodos domésticos de purificación de agua para comunidades de Texas fronterizas con México

Directory of Open Access Journals (Sweden)

Patrick L. Gurian

2006-12-01

Full Text Available This study evaluated user preferences among three alternative in-home water treatment technologies suitable for households relying on trucked water in El Paso County, Texas, which is on the border with Mexico. The three technologies were: chlorination of household storage tanks, small-scale batch chlorination, and point-of-use ultraviolet disinfection. Fifteen households used each of the three technologies in succession for roughly four weeks each during April through June of 2004. Data were collected on treated water quality, and a face-valid survey was administered orally to assess user satisfaction with the technologies on a variety of attributes. Treatment with a counter-top ultraviolet disinfection system received statistically significantly higher ratings for taste and odor and likelihood of future use than the other two approaches. Ultraviolet disinfection and small-scale batch chlorination both received significantly higher ratings for ease of use than did storage tank chlorination. Over-chlorination was a common problem with both batch chlorination and storage tank chlorination. Water quality in the households using trucked water is now higher than was reported by a previous study, suggesting that water quality has improved over time.Este estudio evaluó las preferencias de los consumidores de tres tecnologías domésticas para el tratamiento del agua, apropiadas para viviendas del condado de El Paso, Texas, situado en la frontera con México, que dependen del agua transportada en camiones. Las tres tecnologías fueron cloración de los tanques domésticos de almacenamiento, cloración de pequeños lotes de agua y desinfección mediante luz ultravioleta en el punto de dispensación. Quince viviendas utilizaron sucesivamente cada una de las tres tecnologías durante aproximadamente cuatro semanas entre abril y junio de 2004. Se registraron los datos sobre la calidad del agua tratada y se realizó una encuesta oral aceptada por los

Verificación de la contaminación del maíz por flatoxina B1

Directory of Open Access Journals (Sweden)

Lisa Vallone

2010-10-01

Full Text Available “Aflaflesh” es un instrumento computarizado, diseñado para combinar un metodo de adquisición de datos visuales, con sofisticados sistemas operativosde software y análisis de imágenes. Esto, mediante la exposicion de la fluorescencia de maíz sometido a la radiación UV, ya que si hay contaminación con aflatoxinas B1, es posible transformar directamente el número de pixeles de la fluorescencia, en la concentración de AFB1 correspondiente.

Prevalencia de deshidratación en futbolistas profesionales chilenos antes del entrenamiento

OpenAIRE

Castro-Sepúlveda, Mauricio; Astudillo, Sebastián; Álvarez, Cristian; Zapata-Lamana, Rafael; Zbinden-Foncea, Hermann; Ramírez-Campillo, Rodrigo; Jorquera, Carlos

2015-01-01

Introducción: existen pocos estudios relacionados con el estado de hidratación pre-entrenamiento en futbolistas profesionales. Objetivo: determinar la prevalencia de deshidratación pre-entrenamiento en jugadores profesionales de fútbol. Metodos: se incluyeron un total de 156 jugadores de fútbol (edad 25,4 ± 5,2 años) de seis clubes profesionales chilenos. No se hicieron recomendaciones previas de hidratación ni de ingesta de alimentos, con el objetivo de evaluar el estado de hidratación bajo ...

Cineantropometría: composición corporal y somatotipo de futbolistas que desarrollan su actividad física en equipos de la Comunidad Autónoma de Madrid

OpenAIRE

Herrero de Lucas, Ángel

2004-01-01

Definimos Cineantropometría como el estudio del tamaño, forma, proporcionalidad, composición, maduración biológica y función corporal; con objeto de entender el proceso del crecimiento, el ejercicio, el rendimiento deportivo y la nutrición. OBJETIVOS: Estudio controlado, transversal, no randomizado, de tipo observacional y analítico cineantropométrico. MATERIAL Y METODO: Utilizamos el protocolo de medidas establecido por la Sociedad Internacional para el Avance de la Cineantropometría (I.S.A....

METODE POSPEŠEVANJA PRODAJE NOVEGA KOZMETIČNEGA IZDELKA V PODJETJU X

OpenAIRE

Krampač, Barbara

2012-01-01

Zadnja leta pospeševanje prodaje beleži precej strmo rast, katere primarna dejavnost je spodbujanje potrošnika k nakupu. Uporablja jo velika večina proizvajalcev, trgovcev na debelo in drobno ter ostale organizacije. Pravilna uporaba lahko privede do boljše prepoznavnosti posamezne blagovne znamke in zadovoljitev kupčevih potreb. V Podjetju X izvajamo različne aktivnosti, katere s pomočjo proizvajalca organiziramo izključno sami. Uporabljamo metodo znižanih cen, preizkušanj, daril, preds...

Características dieléctricas de diversos polímeros (PVC, EVA, HDPE, y PP) reforzados con neumáticos fuera de uso (GTR)

OpenAIRE

Mujal-Rosas, R.; Orrit-Prat, J.; Ramis-Juan, X.; Marin-Genesca, M.; Rahhali, Ahmed

2011-01-01

La masiva fabricación de neumáticos y la dificultad para su almacenamiento o eliminación constituye un grave problema medioambiental. En la actualidad, se utilizan diversos metodos para el reciclaje de los neumáticos, como por ejemplo la trituración mecánica, que separa el caucho vulcanizado del acero y las fibras, utilizandose este caucho en numerosas aplicaciones industriales como pavimentos, aislantes, calzados, etc. El presente artículo se centra en buscar una nueva aplicación para estos ...

Influencia de los factores individuales de los pacientes diagnosticados de esquizofrenia en la presencia de violencia laboral en unidades de salud mental

OpenAIRE

Quílez Jover, Jorge; Icart Isern, M. Teresa (Maria Teresa)

2015-01-01

Objetivo: evaluar la información disponible en materia de factores de riesgo que influyen en que los pacientes diagnosticados de esquizofrenia ingresados en unidades de salud mental mantengan conductas violentas hacia el personal de Enfermena. Metodo: la búsqueda de artículos se ha realizado en las bases de datos electronicas PubMed, CINAHL y la plataforma Scopus desde enero de 1998 hasta 2013. Se han incluido estudios en lengua inglesa, francesa o española que evalúen la influencia de los fa...

Squamous-lined cyst of the pancreas: Radiological–pathological correlation

International Nuclear Information System (INIS)

Kubo, T.; Takeshita, T.; Shimono, T.; Hashimoto, S.; Miki, Y.

2014-01-01

Pancreatic cystic lesions are increasingly being detected incidentally because of the increased use of cross-sectional imaging. Squamous-lined cysts of the pancreas (lymphoepithelial cyst, epidermoid cyst, and dermoid cyst) are rare cystic lesions lined with squamous epithelium. Distinguishing squamous-lined cysts from other cystic lesions of the pancreas is important to avoid unnecessary surgery, because squamous-lined cysts of the pancreas have no malignant potential. The purpose of this review is to describe findings on computed tomography and magnetic resonance imaging and the histopathological characteristics of squamous-lined cysts, and to summarize the key points of differential diagnosis for pancreatic cystic lesions

Giant Ulcerative Dermatofibroma

Directory of Open Access Journals (Sweden)

Turgut Karlidag

2013-01-01

Full Text Available Dermatofibroma is a slowly growing common benign cutaneous tumor characterized by hard papules and nodules. The rarely seen erosions and ulcerations may cause difficulties in the diagnosis. Dermatofibrosarcoma protuberans, which is clinically and histopathologically of malignant character, displays difficulties in the diagnosis since it has similarities with basal cell carcinoma, epidermoid carcinoma, and sarcomas. Head and neck involvement is very rare. In this study, a giant dermatofibroma case, which is histopathologically, ulcerative dermatofibroma, the biggest lesion of the head and neck region and seen rarely in the literature that has characteristics similar to dermatofibrosarcoma protuberans, has been presented.

Complicaciones tardías de la radioterapia ocular

OpenAIRE

González García, Julio Lázaro; Santos Silva, Dania; Abreu Perdomo, Franklyn Alain; Melgares Ramos, María de los Ángeles; Valdivia Bregado, Yamelyn Tania

2016-01-01

La radioterapia es uno de los pilares terapéuticos utilizados en la oncología, no exenta de producir daño ocular, lo que constituye un fenómeno bien establecido. La aparición de complicaciones continúa siendo la principal preocupación de la aplicación de la radioterapia, a pesar del empleo de nuevas estrategias que buscan reducir las complicaciones y mejorar el índice terapéutico. Se presenta una paciente femenina de 63 años con diagnóstico de carcinoma epidermoide de la conjuntiva, moderadam...

Cerebral Arachnoid Cysts

Directory of Open Access Journals (Sweden)

Ersin Haciyakupoglu

2016-09-01

Full Text Available Arachnoid cysts can occur through inflammatory, traumatic, chemical irritation, skin tumor and postoperative processes. It is diagnosed and differentiated by magnetic resonance imaging and computerized tomography from other lesions. Its differential diagnosis includes colloid cyst , craniopharyngioma, prosencephaly, holoprosencephaly , epidermoid cyst, hydatid cyst, low grade glial tumors, infarcts and subdural hygroma. Most of them are asymptomatic and diagnosed incidentally. Treatment methods such as simple cyst aspiration , total excision of the cyst, basal cysternostomy, ventricular fenestration, cysto or ventriculoperitoneal shunt can be performed by various endoscopic surgery and craniotomy. [Archives Medical Review Journal 2016; 25(3.000: 259-268

Experiencia de 10 años en el manejo del cáncer de pene, Instituto Nacional del Cáncer (1997-2006)

OpenAIRE

NEVEU C,RODRIGO; BÓRQUEZ M,PABLO; TRUJILLO L,CRISTIÁN; FERNÁNDEZ R,ROBERTO; BUCHHOLTZ F,MARTIN

2008-01-01

Introducción: El cáncer epidermoide de pene es una enfermedad infrecuente en occidente, sin embargo tiene alta incidencia en algunos países de Latinoamérica, África y Asia. Se le considera una patología asociada a ciertas costumbres higiénicas y pobres condiciones socioeconómicas. En Chile no hay cifras reales de incidencia del cáncer de pene, pero pareciera ser baja; esto además dificulta la generación de guías y ensayos clínicos para determinar cual es el mejor manejo de los casos que se pr...

Quiste epidérmico de inclusión de párpado. Presentación de 2 casos

OpenAIRE

Eréndira Güemez Sandoval; Fátima Cedillo Azuela; Rosalba García Ramírez

2017-01-01

El quiste epidérmico de inclusión o quiste epidermoide es una lesión intraepitelial, redonda u ovalada, de color amarillo, de crecimiento progresivo y consistencia suave; de diversa etiología, se origina por la proliferación de las células epidérmicas superficiales dentro de la dermis y su contenido es queratina. Se presenta frecuentemente en los párpados. El diagnóstico se realiza por la clínica y por el estudio histopatológico; el tratamiento es con escisión quirúrgica completa.

Neuroimaging Features of San Luis Valley Syndrome

Directory of Open Access Journals (Sweden)

Matthew T. Whitehead

2015-01-01

Full Text Available A 14-month-old Hispanic female with a history of double-outlet right ventricle and developmental delay in the setting of recombinant chromosome 8 syndrome was referred for neurologic imaging. Brain MR revealed multiple abnormalities primarily affecting midline structures, including commissural dysgenesis, vermian and brainstem hypoplasia/dysplasia, an interhypothalamic adhesion, and an epidermoid between the frontal lobes that enlarged over time. Spine MR demonstrated hypoplastic C1 and C2 posterior elements, scoliosis, and a borderline low conus medullaris position. Presented herein is the first illustration of neuroimaging findings from a patient with San Luis Valley syndrome.

Inventory Methods in a Conversion Plant; Methodes d'Inventaire dans un Etablissement de Transformation; Metody inventarizatsij na predpriyatii po pererabotke yadernykh materialov; Metodos de Inventario en una Planta de Transformacion

Energy Technology Data Exchange (ETDEWEB)

Billy, G. [Commissariat a l' Energie Atomique, Paris (France)

1966-02-15

inventarios es la de salvaguardar los intereses de la Comision, evaluar la cuantia de las perdidas y controlar las medidas adoptadas para el almacenaje de los desechos. Para el recuento de las existencias el inspector puede efectuar materialmente el inventario, participar en el o comprobarlo. Este ultimo procedimiento es el que da mejores resultados. Las operaciones de recuento, precedidas de una reunion preparatoria para fijar las modalidades, se efectuan en dos tiempos: la comprobacion del inventario ponderal y la comprobacion de la contabilidad fisica. Las cuestiones que pueden plantearse durante el inventario se refieren a las discrepancias en el peso y el contenido, la eleccion del equipo de pesada, los residuos y la evaluacion de las perdidas. Los metodos de inventario no deben diferir de un pais a otro. Parece preferible subrayar las dificultades que se presentan durante las operaciones y estudiar en comun los medios para evitarlas. (author) [Russian] Osnovnymi zadachami inventarizacii javljajutsja: sobljudenie interesov Komissariata; opredelenie razmerov poter'; kontrol' mer, prinimaemyh dlja hranenija othodov. Inspektirujushhee lico mozhet provodit' fakticheskuju inventarizaciju, uchastvovat' v nej ili proverjat' ee. Jetot poslednij metod daet nailuchshie rezul'taty. Operacii po uchetu, kotorym predshestvuet podgotovitel'noe soveshhanie dlja opredelenija sposobov ucheta, provodjatsjav dva jetapa: snachala proverjaetsja nalichie po vesu, azatemdoku mentacija. Voprosy, voznikajushhie v svjazi s inventarizaciej i kasajushhiesja vesa, soderzhanija poko- vok, vybora vesov dlja vzveshivanija, normy othodov i ocenki poter', razreshajutsja otpravite- lem i poluchatelem. Metody inventarizacii v odnom gosudarstve ne dolzhny sil'no otlichat'sja ot takovyh v drugom gosudarstve. Neobhodimo podcherknut' trudnosti, voznikajushhie v processe inven- tarizacii, i zhelatel'nost' otyskanija sovmestnyh putej ih preodolenija. (author)

Estudio de la fiabilidad mediante ensayos acelerados de diodos ultravioletas de alta potencia

OpenAIRE

Segura Antúnez, César

2014-01-01

Durante los últimos años la utilización de los LEDs (Light Emitting Diodes) ha aumentado de forma muy importante siendo hoy en día una alternativa real a los sistemas de iluminación tradicionales. La iluminación basada en LEDs se está utilizando ampliamente en automoción, arquitectura, aplicaciones domésticas y señalización debido a su alta fiabilidad, pequeño tamaño y bajo consumo. La evaluación de la fiabilidad de los LEDs es un tema clave previo a la comercialización o a la puesta en...

Análise da medição do raio solar em ultravioleta

Science.gov (United States)

Saraiva, A. C. V.; Giménez de Castro, C. G.; Costa, J. E. R.; Selhorst, C. L.; Simões, P. J. A.

2003-08-01

A medição acurada do raio solar em qualquer banda do espectro eletromagnético é de relevância na formulação e calibração de modelos da estrutura e atmosfera solar. Esses modelos atribuem emissão do contínuo do Sol calmo em microondas à mesma região da linha Ha do Hell. Apresentamos a medição do raio solar em UV com imagens do EIT (Extreme Ultraviolet Image Telescope) entre 1996 e 2002, no comprimento de onda 30,9 nm (Ha do Hell), que se forma na região de transição/cromosfera solar. A técnica utilizada para o cálculo do raio UV foi baseada na transformada Wavelet B3spline. Fizemos um banco de dados com 1 imagem por dia durante o período citado. Obtivemos como resultado o raio médio da ordem de 975.61" e uma diminuição do mesmo para o período citado variando em média -0,45" /ano. Comparamos estes dados com os valores obtidos pelo ROI (Radio Observatório de Itapetinga) em 22/48 GHz e Nobeyama Radio Heliograph em 17 GHz mostrando que os raios médios são muito próximos o que indica que a região de formação nessas freqüências é a mesma conforme os modelos. Comparamos os resultados também com outros índices de atividade solar.

Zinc Selenide-Based Schottky Barrier Detectors for Ultraviolet-A and Ultraviolet-B Detection

Directory of Open Access Journals (Sweden)

V. Naval

2010-01-01

Full Text Available Wide-bandgap semiconductors such as zinc selenide (ZnSe have become popular for ultraviolet (UV photodetectors due to their broad UV spectral response. Schottky barrier detectors made of ZnSe in particular have been shown to have both low dark current and high responsivity. This paper presents the results of electrical and optical characterization of UV sensors based on ZnSe/Ni Schottky diodes fabricated using single-crystal ZnSe substrate with integrated UV-A (320–400 nm and UV-B (280–320 nm filters. For comparison, characteristics characterization of an unfiltered detector is also included. The measured photoresponse showed good discrimination between the two spectral bands. The measured responsivities of the UV-A and UV-B detectors were 50 mA/W and 10 mA/W, respectively. A detector without a UV filter showed a maximum responsivity of about 110 mA/W at 375 nm wavelength. The speed of the unfiltered detector was found to be about 300 kHz primarily limited by the RC time constant determined largely by the detector area.

Some resistance mechanisms to ultraviolet radiation; Algunos mecanismos de resistencia a radiacion ultravioleta

Energy Technology Data Exchange (ETDEWEB)

Alcantara D, D. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)

2002-12-15

The cyclical exposure of bacterial cells to the ultraviolet light (UV) it has as consequence an increment in the resistance to the lethal effects of this type of radiation, increment that happens as a result of a selection process of favorable genetic mutations induced by the same UV light. With object to study the reproducibility of the genetic changes and the associate mechanisms to the resistance to UV in the bacteria Escherichia coli, was irradiated cyclically with UV light five different derived cultures of a single clone, being obtained five stumps with different resistance grades. The genetic mapping Hfr revealed that so much the mutation events like of selection that took place during the adaptation to the UV irradiation, happened of random manner, that is to say, each one of the resistant stumps it is the result of the unspecified selection of mutations arisen at random in different genes related with the repair and duplication of the DNA. (Author)

Efeito do ácido bórico sobre a velocidade da reação do 2-hidroxibenzaldéido com nucleófilos nitrogenados

OpenAIRE

Simionatto, Edesio Luiz

1997-01-01

Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em Química O ácido bórico acelera a reação de formação da oxima derivada do 2-hidroxibenzaldeído. Os resultados cinéticos e a análise por espectroscopia ultravioleta, sugerem, que o efeito do ácido bórico é sobre o estado de transição da etapa de desidratação da reação, através da formação de um complexo com o intermediário de adição formado pelo rápido equilíbrio ...

Photosynthetic carbon reduction by seagrasses exposed to ultraviolet A radiation

Science.gov (United States)

1979-01-01

The seagrasses Halophila engelmannii, Halodule wrightii, and Syringodium filiforme were examined for their intrinsic sensitivity to ultraviolet-A-UV-A and ultraviolet-B-UV-B radiation. The effect of UV-A on photosynthetically active radiation (PAR) was also determined. Ultraviolet-A and ultraviolet-B were studied with emphasis on the greater respective environmental consequence in terms of seagrass distribution and abundance. Results indicate that an intrinsic sensitivity to UV-A alone is apparent only in Halophila, while net photosynthesis in Halodule and Syringodium seems unaffected by the level of UV-A provided. The sensitivity of Halophila to UV-A in the absense of (PAR) indicates that the photosynthetic reaction does not need to be in operation for damage to occur. Other significant results are reported.

Pono tibi istam: “Tu curris”.Uno sguardo alla teoria medievale delle obbligazioni

Directory of Open Access Journals (Sweden)

Riccardo Strobino

2008-12-01

Full Text Available La teoria delle obbligazioni rappresenta un significativo esempio di come un insieme di tecniche logiche possa essere applicato, in maniera feconda, a contesti disputazionali in cui la dimensione dialogica e l’interazione tra soggetti coinvolti in un confronto dialettico hanno un ruolo di primo piano. L’attenzione che numerosi studiosi hanno manifestato nei confronti di questa parte della logica modernorum negli ultimi quarat’anni testimonia la profondità e la difficoltà dei problemi teorici che stanno alla base della teoria. Molte interpretazioni sono state avanzate circa le motivazioni che spingono i logici medievali a scrivere trattati in cui il portato delle loro dottrine logiche – come, ad esempio, la teoria delle consequentiae - viene declinato ed elaboratamente applicato al gioco dialettico tra due disputanti. La gamma di tali letture comprende differenti ipotesi: la teoria delle obbligazioni potrebbe fornire un nucleo di regole per l’impostazione di un metodo assiomatico rudimentale così come rappresentare un tentativo di elaborare esercizi volti a valutare le capacità logiche degli studenti o, ancora, un gioco teorico, svincolato dall’effettiva applicazione a contesti concreti, la cui finalità sarebbe il mantenimento della coerenza logica. E’ stata sostenuta da più interpreti la funzione pedagogica svolta dalla teoria, al di là del fatto che si tratti o meno di un metodo per la conduzione effettiva di dispute reali. Un’altra linea interpretativa collega la teoria delle obbligazioni al contesto della letteratura dei sophismata e degli insolubilia, dal cui repertorio, in effetti, sono spesso tratti molti degli esempi che si incontrano nella lettura dei trattati de obligationibus. In questo senso, la teoria offrirebbe regole e schemi di risposta che un interlocutore deve utilizzare per risolvere o rispondere a enunciati problematici o paradossali. Non si può escludere, inoltre, che nella teoria si realizzi un

Sonochemical synthesis of a PdAg/C electrocatalyst for oxygen reduction reaction; Sintesis sonoquimica de un electrocatalizador de PdAg/C para la reaccion de reduccion de oxigeno

Energy Technology Data Exchange (ETDEWEB)

Godinez-Garcia, A.; Perez-Robles, J.F. [Centro de Investigacion y de Estudios Avanzados del IPN. Santiago de Queretaro, Queretaro (Mexico)]. E-mail: jperez@qro.cinvestav.mx; Solorza-Feria, O. [CINVESTAV-IPN, Mexico, D.F. (Mexico)

2009-09-15

The synthesis and characterization of nanocatalysts for fuel cells has been a primary line of research for the purpose of obtaining less expensive electrocatalysts with better activity. A large variety of methods exist to synthesize useful nanoparticles as electrocatalysts. Each method generates particles with a different surface morphology and, therefore, the catalytic activity usually varies depending on which is used in the synthesis. In this work, PdAg/C electrocatalysts are synthesized with high-intensity ultrasonic irradiation and compared to those obtained using a conventional method such as reduction by NaBH{sub 4}. The study of this technique is of interest because it produces highly dispersed carbon-supported nanoparticles with very clean surfaces. Each electrocatalyst was evaluated for its oxygen reduction reaction (ORR) in acid medium with cyclic voltamperometry (CV) and rotating disc electrode (RDE). The electrocatalyst was characterized with x-ray diffraction and transmission electron microscopy (TEM). The physical characterization reveals that the electrocatalyst is composed of nanometric bimetallic aggregates. An important characteristic of the PdAg/C alloy obtained using ultrasound is better activity than that obtained by reduction with NaBH{sub 4}. [Spanish] La sintesis y caracterizacion de nanocatalizadores para celdas de combustible ha sido una de las principales lineas de investigacion, con el objetivo de obtener electrocatalizadores mas baratos y con una mejor actividad. Existen una gran variedad de metodos para sintetizar nanoparticulas utiles como electrocatalizadores, cada metodo genera particulas con una morfologia superficial diferente por lo que la actividad catalitica suele variar dependiendo de cual se utilice en la sintesis. En este trabajo se sintetizan electrocatalizadores de PdAg/C con irradiacion ultrasonica de alta intensidad y se comparan con las obtenidas con un metodo convencional como es la reduccion por NaBH{sub 4}. Esta

Analysis of the indices of thermal comfort for the conditions of the Mexican Republic; Analisis de los indices de confort termico para las condiciones de la republica mexicana

Energy Technology Data Exchange (ETDEWEB)

Fuentes Freixanet, Victor; Rodriguez Viqueira, Manuel [Universidad Autonoma Metropolitana - Unidad Azcapotzalco (Mexico)

2009-07-15

The objective of this article is to analyze different indices of thermal comfort for the Mexican Republic. Among them the Fanger (PMV and PPD) physiological methods of comfort and the new effective temperature index are included. The standard effective temperature (SET), as well as the adaptive methods of Humphreys and Nicol, Auliciems, De Dear and Brager. A comparative analysis is done of the different indices through thematic maps determined by interpolation, using a climatic data base of 700 cities obtained from the observatories and stations of the National Meteorological Service. This article pretends to establish general criteria of the thermal comfort to later define design strategies for each one of the climatic regions of the Mexican Republic. [Spanish] El objetivo de este articulo es analizar distintos indices de confort termico para la Republica Mexicana. Entre ellos se incluyen los metodos fisiologicos de confort de Fanger (PMV y PPD), el indice de nueva temperatura efectiva. La temperatura efectiva estandar (SET), asi como los metodos adaptativos de Humphreys y Nicol, Auliciems, De Dear y Brager. Se hace un analisis comparativo de los distintos indices a traves de mapas tematicos determinados por interpolacion, usando una base de datos climaticos de 700 ciudades obtenidos de los observatorios y estaciones del Servicio Meteorologico Nacional. Este articulo presenta establecer criterios generales del confort termico para posteriormente definir estrategias de diseno para cada una de las regiones climaticas de la Republica Mexicana.

Preliminary study for the determination of heavy metal in ground samples by GF-ASS Zeeman; Studio preliminare per la determinazione di metalli pesanti in campioni di suolo mediante analisi GF-AAS Zeeman

Energy Technology Data Exchange (ETDEWEB)

Casabianca, T.; Bitonte, R.; Epifani, M.; Ubaldi, C. [ENEA, Divisione Tecnologie Ingegneria e Servizi Ambientali, Centro Ricerche Trisaia, MT (Italy)

2001-07-01

In the framework of SIMOA project have been investigated methods to evaluate the level of soil contamination due to heavy metals. In this wok, it is discussed a procedure to measure topsoil bioavailable fraction of seven heavy metals (Cd, Cu, Pb, Ni, Cr, Hg). The adopted procedure is based on acid digestion followed by instrumental detection by means of graphite furnace atomic-absorption spectrophotometry (GFAAS) using Zeeman effect to reduce background contribution. Details of samples preparation and analysis, experimental setup optimization and statistical data analysis are presented, together with a discussion on method accuracy and data interpretation. [Italian] Nell'ambito del progetto SIMOA (Sistema Integrato di Monitoraggio Ambientale) per il monitoraggio ambientale nel bacino del Basento (Regione Basilicata, Italia), vengono investigati i metodi per il controllo dei livelli di inquinamento del suolo da parte di metalli pesanti. Nel presente lavoro viene proposta una procedura per determinare il livello di concentrazione della frazione biodisponibile di sette metalli pesanti (Cadmio, Rame, Piombo, Nickel, Cromo, Mercurio) in campion di suolo superficiale. Il metodo e' basato su di un trattamento di digestione acida in forno a microonde cui segue la rivelazione strumentale mediante spettrofotometria di assorbimento atomico in fornetto di grafite (GFAAS) con effetto Zeeman per la correzione del fondo. Si descrivono in dettaglio le fasi di preparazione dei campioni, la metodologia di misura e l'analisi statistica dei dati, oltre ad una discussione sull'attendibilita' del metodo e sui futuri sviluppi.

Manufacture of amorphous and poly-crystalline materials with the sol-gel process; Fabricacion de materiales amorfos y policristalinos con la ruta sol-gel

Energy Technology Data Exchange (ETDEWEB)

Castaneda-Contreras, J. [Centro Universitario de Los Lagos, Universidad de Guadalajara, Guadalajara, Jalisco (Mexico)

2006-01-15

The sun-gel process is a chemical route that allows the manufacture of amorphous and poly-crystalline materials in a relatively simple way. New materials can be obtained, materials that through the traditional manufacture methods, are very difficult to obtain, such as oxide combinations (SiO{sub 2}, TiO{sub 2}, ZrO{sub 2}, etc.), and that, when being produced by traditional methods, they run the risk of being contaminated with rare earth ions or organic dyes. The unique structures, micro- structures and compounds that can be made with the sun-gel process open many possibilities for practical applications, to name a few: the manufacture of optical components, preforms for optical fibers, dielectric coatings, superconductors, waveguides, nanoparticles, solar cells, etc. [Spanish] El proceso sol-gel es una ruta quimica que permite fabricar materiales amorfos y policristalinos de forma relativamente sencilla. Se pueden obtener nuevos materiales que a traves de los metodos tradicionales de fabricacion son muy dificiles de obtener, tales como combinaciones de oxidos (SiO{sub 2}, TiO{sub 2}, ZrO{sub 2}, etc.), y que, de ser producidos por metodos tradicionales corren el riesgo de contaminarse con iones de tierras raras o colorantes organicos. Las estructuras unicas, micro estructuras y compuestos que pueden hacerse con el proceso sol-gel abren muchas posibilidades para aplicaciones practicas, por nombrar algunas, la fabricacion de componentes opticos, preformas para fibras opticas, recubrimientos dielectricos, superconductores, guias de onda, nanoparticulas, celdas solares, etc.

Ocena potresne odpornosti družinske hiše v Grosuplju

OpenAIRE

Žitnik, Luka

2017-01-01

V diplomski nalogi je predstavljena ocena potresne odpornosti zidane hiše v Grosuplju. Potresno analizo smo izvedli z metodo horizontalnih sil na podlagi zahtev, ki jih podajata standarda Evrokod 6 in Evrokod 8. Diploma je razdeljena na teoretični in praktični del. V teoretičnem delu so predstavljeni postopki za določitev potresne obtežbe, račun nosilnosti posameznih zidov ter oceno odpornosti celotne konstrukcije. Povečanje obremenitve zaradi vpliva slučajne ekscentričnosti smo upoštevali na...

RAST PODJETJA S POMOČJO FRANŠIŽE NA PRIMERU PODJETJA MERCATOR D.D.

OpenAIRE

Podgoršek, Nuša

2013-01-01

Podjetja lahko rastejo na zelo različne načine, vendar v podjetju lahko nastane rast na pasiven ali aktiven način. Možno je tudi da določena podjetja sploh ne rastejo. Rast podjetja pa predstavlja tudi ključen pomen, ki prispeva tudi k razvoju gospodarstva, ustvarjanju novih delovnih mest in dvigu nivoja družbenega blagostanja. V diplomskem seminarju smo poskušali pokazati, da podjetje lahko raste s pomočjo franšiznega sistema. Franšizing predstavlja metodo, kjer na osnovi franšizne pogo...

Prevalencia de obesidad y factores de riesgo cardiovascular en estudiantes de ciencias de la salud - universidad del Quindío - 2013

OpenAIRE

Zapata Barreto, Carlos Javier; Zamudio Suarez, Sandra Catalina; Velasquez Millan, Monica María; Ortegon Mantilla, Marilse Paola

2013-01-01

ANTECEDENTES: En Colombia, reportes del año 2010 de la Encuesta Nacional de la Situación en Nutrición ENSIN 2010(2), muestran uno de cada dos colombianos, presentan un índice de masa corporal mayor al esperado (3) METODO: El presente estudio de corte transversal, determino la prevalencia de obesidad y otros factores de riesgo cardiovascular en una población de estudiantes de Ciencias de la Salud de una Universidad regional en el primer periodo académico del año 2013. El tamaño de muestra...

Determinación de aminas aromaticas por cromatografia liquida de alta resolución.

OpenAIRE

Gutiérrez Bouzán, Mª Carmen; Crespi Rosell, Martí

1989-01-01

Este trabajo consiste en la puesta a punto del metodo analítico para la determinación por cromatografia liquida de alta resolución (HPLC) de las aminas aromáticas empleadas más frecuentemente en la fabricación de colorantes sulfurosos: m-tolilendiamina, p-fenilendiamina, o-toluidina, p-toluidina, anilina, p-aminofenol, difenilamina, y p-hidroxidifenilamina. La longitud de onda de detección es de 260 nm. El principal objetivo del presente estudio es la consecución de un método de análisis p...

PREPREČEVANJE VENTILATORSKE PLJUČNICE

OpenAIRE

Mori, Jernej

2016-01-01

Ventilatorska pljučnica (VAP) je med najpogostejšimi zapleti pri pacientih, ki ležijo v intenzivni enoti in so priklopljeni na mehanično ventilacijo. VAP podaljša ležalno dobo na intenzivni enoti, pogosto povzroči smrt pacienta in predstavlja velik dodaten strošek za zdravstveni sistem. Namen diplomskega dela je bil opisati in predstaviti ukrepe za preprečevanje VAP. V diplomskem delu smo uporabili deskriptivno (opisno) metodo dela, pri kateri nam je bila v pomoč domača, predvsem pa tuja lite...