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Sample records for methods references discuss

  1. DISCUSSION METHODS: MODIFICATION AND TRANSFORMATION

    Directory of Open Access Journals (Sweden)

    A A Abbasova

    2015-12-01

    Full Text Available The article is devoted to the importance of selecting the optimal methods of stimulation and motivation for learning. In modern conditions it is very important that the teacher did not give the students ready knowledge, but pointed out the way for the acquisition of knowledge, taught them to gain knowledge. This demands from the philologist the choice of effective forms of working with texts of different types and styles of speech, listening, speaking. In this connection a special attention should be paid to the lessons of speech development. There is a special group of methods to stimulate the development of communicative competence. Among them, the method of discussion, which is increasingly being used during the Russian language lessons. The specificity of using this method in class for teaching Russian as a foreign language, its basic functions (teaching, developing, educating are considered. The key rules for conducting a discussion at the Russian language classes, the main and additional functions-roles of the teacher, the participants, the minute-taker are analyzed. The advantages of the discussion in Russian in comparison to the discussion in the students’ native language are summarized.

  2. DISCUSSION METHODS: MODIFICATION AND TRANSFORMATION

    Directory of Open Access Journals (Sweden)

    Abbasova, A.A.

    2016-03-01

    Full Text Available This article is about how to the importance of selecting the optimal methods of stimulation and motivation to learn. In modern conditions it is very important that the teacher gave the students ready knowledge, and pointed the way for the acquisition of knowledge, taught to acquire knowledge. This requires the selection of effective forms of language and literature work with texts of different types and styles of speech, listening, speaking. In this regard, special attention should be given lessons of speech development. There is a special group of methods to stimulate the development of communicative competence. Among them, and the method of discussion, which is increasingly being used in the classroom in the Russian language

  3. testing a consensus conference method by discussing

    African Journals Online (AJOL)

    hi-tech

    2000-10-10

    Oct 10, 2000 ... Objectives: To test the recommended consensus conference methods in Tanzania by discussing the management ... “wrong”, based on recommendations advocated in western ..... future scenarios sponsored the conference.

  4. Creative Research Methods - a reflective online discussion

    Directory of Open Access Journals (Sweden)

    Ruth Leary

    2014-03-01

    Full Text Available In November 2013, the Institute of Advanced Studies (University of Warwick hosted a meeting of interdisciplinary colleagues interested in Creative Research Methods. The aspirations were to kick-start the debate at Warwick and create a platform from which researchers can develop projects that embrace new forms of intellectual enquiry and knowledge production. Following the meeting, several of the attendees agreed to develop some of the discussion points and briefly responded to a number of questions in an online document over a period of a few weeks. This paper is the result of that real space and online collaboration.

  5. Automatic Annotation Method on Learners' Opinions in Case Method Discussion

    Science.gov (United States)

    Samejima, Masaki; Hisakane, Daichi; Komoda, Norihisa

    2015-01-01

    Purpose: The purpose of this paper is to annotate an attribute of a problem, a solution or no annotation on learners' opinions automatically for supporting the learners' discussion without a facilitator. The case method aims at discussing problems and solutions in a target case. However, the learners miss discussing some of problems and solutions.…

  6. A discussion of some aspects of the MCSCF method

    International Nuclear Information System (INIS)

    Shepard, R.

    1992-01-01

    After a brief overview of the MCSCF (Multi-Configuration Self- Consistent-Field) method, a more detailed examination of the underlying model is undertaken. The problem of ''multiple solutions'' is examined with reference to the ''symmetry-breaking'' problem and with emphasis on single-state cases. It is argued that the most appropriate resolution of such problems is usually case-specific, and depends on the details of how the MCSCF wave function is being used to model the chemical system rather than on features characteristic of the MCSCF wave function itself. Finally, a recently introduced MCSCF wave function optimization method based on multidimensional trigonometric interpolation is briefly discussed

  7. Discussion

    International Nuclear Information System (INIS)

    Sutcliffe, W.G.

    1991-01-01

    This is an edited transcript of the recorded discussions that followed the presentation of each paper and on the general comments at the conclusion of the session. No attempt was made to identity those who offered comments or asked questions

  8. Refer to AP1000 for discussing the betterment of seismic design of internal nuclear power plant

    International Nuclear Information System (INIS)

    Gong Zhenbang; Zhang Renyan

    2014-01-01

    As a reference technique of AP1000, This paper discussed the betterment of seismic design of nuclear power plant in three ways. (1) Establish design criteria and guidelines for protection from seismic interaction; (2) Nuclear power plant seismic design of eliminating or weaken operation-basis earthquake; (3) Develop the seismic margin analysis (SMA) of the nuclear power plant. These three aspect are frontier technology in internal seismic design of internal nuclear power plant, and also these three technology are related intimately. (authors)

  9. Needs for fundamental atomic reference data and data distribution — a collage of discussions

    Science.gov (United States)

    Boumans, P. W. J. M.

    This article reports, in edited form, the discussions following a series of presentations during a Workshop " Needs for Fundamental Atomic Reference Data for Analytical Spectroscopy". This report forms part of the complete Proceedings of the Workshop, in which the extended and edited texts of the presentations, along with the conclusions, are bundled [ Spectrochim. Acta43B, No. 1 (1988)]. In the present "collage", the discussions are grouped under the following headings: (a) targets of the workshop, (b) distribution of the questionnaire, (c) data compilation, (d) clearinghouse for data — accuracy and critical evaluation of data — confidence in data, (e) spectral simulation — partition functions — COSMIC program —understanding the ICP, (f) work at the National Bureau of Standards (NBS) — information on NBS publications, (g) approaches to and instruments for data compilation — multielement interference corrections, (h) type of database and database manager, (i) atomic fluorescence spectrometry - Rydberg states, and (j) transient discharges.

  10. Comparison of microstickies measurement methods. Part II, Results and discussion

    Science.gov (United States)

    Mahendra R. Doshi; Angeles Blanco; Carlos Negro; Concepcion Monte; Gilles M. Dorris; Carlos C. Castro; Axel Hamann; R. Daniel Haynes; Carl Houtman; Karen Scallon; Hans-Joachim Putz; Hans Johansson; R. A. Venditti; K. Copeland; H.-M. Chang

    2003-01-01

    In part I of the article we discussed sample preparation procedure and described various methods used for the measurement of microstickies. Some of the important features of different methods are highlighted in Table 1. Temperatures used in the measurement methods vary from room temperature in some cases, 45 °C to 65 °C in other cases. Sample size ranges from as low as...

  11. A discussion of molecular biology methods for protein engineering

    CSIR Research Space (South Africa)

    Zawaira, A

    2011-09-01

    Full Text Available A number of molecular biology techniques are available to generate variants from a particular start gene for eventual protein expression. The authors discuss the basic principles of these methods in a repertoire that may be used to achieve...

  12. Socratic Questioning in the Paideia Method to Encourage Dialogical Discussions

    Science.gov (United States)

    Davies, Maree; Sinclair, Anne

    2014-01-01

    This study focused on the impact of using Socratic questioning, based on the Paideia Method, on the nature of middle-schools students' patterns of interaction and on the cognitive complexity of their discussions. The hypothesis is that an experimental group will increase in both interaction focus and complexity at T3, which is the face-to-face…

  13. Discussion on accuracy of weld residual stress measurement by neutron diffraction. Influence of strain free reference

    International Nuclear Information System (INIS)

    Suzuki, Hiroshi; Akita, Koichi

    2012-01-01

    It is required to evaluate a strain-free reference, α 0 , to perform accurate stress measurement using neutron diffraction. In this study, accuracy of neutron stress measurement was quantitatively discussed from α 0 evaluations on a dissimilar metal butt-weld between a type 304 austenitic stainless steel and an A533B low alloy ferritic steel. A strain-free standard specimen and a sliced specimen with 10 mm thickness taken from the dissimilar metal butt-weld were utilized. In the lattice constant evaluation using the standard specimen, average lattice constant derived from multiple hkl reflections was evaluated as the stress-free reference with cancelling out an intergranular strain. Comparing lattice constant distributions in each reflection with average lattice constant distribution in the standard specimen, αFe211 and γFe311 reflections were judged as a suitable reflection for neutron strain measurement to reduce intergranular strain effects. Residual stress distribution in the sliced specimen evaluated using α 0 measured here exhibited higher accuracy than that measured using strain gauges. On the other hand, α 0 distributions were evaluated using the sliced specimen under the plane-stress condition. Existence of slight longitudinal residual stresses near the weld center decreased accuracy of the α 0 evaluations, which means that it is required to optimize the thickness of the sliced specimen for accurate α 0 evaluation under plane strain condition. As a conclusion of this study, it was confirmed that procedures of accurate α 0 evaluation, optimization of the measurement condition, and multiple evaluations on the results play an important role to improve accuracy of the residual stress measurement using neutron diffraction. (author)

  14. [Discussion paper on participation and participative methods in gerontology].

    Science.gov (United States)

    Aner, Kirsten

    2016-02-01

    The concept of "participation" and the demand for the use of "participative methods" in human, healthcare, nursing and gerontological research as well as the corresponding fields of practice are in great demand; however, the targets and organization of "participation" are not always sufficiently explicated. The working group on critical gerontology of the German Society of Gerontology and Geriatrics uses this phenomenon as an opportunity for positioning and develops a catalogue of criteria for reflection and assessment of participation of elderly people in science and practice, which can also be considered a stimulus for further discussions.

  15. Discussion paper on participation and participatory methods in gerontology.

    Science.gov (United States)

    Aner, K

    2016-12-01

    The concept of "participation" and the use of "participatory methods" in human, healthcare, nursing, and gerontological research, as well as the corresponding fields of practice, represent an expanding field of interest. However, the objectives and organization of "participation" are not always sufficiently explicated. The Critical Gerontology Working Group of the German Society of Gerontology and Geriatrics presents a statement on this phenomenon, and proposes a catalogue of criteria for reflection upon and assessment of participation by older people in research and practice, which can also be considered a stimulus for further discussions.

  16. Discussion on Implementation of ICRP Recommendations Concerning Reference Levels and Optimisation

    International Nuclear Information System (INIS)

    2013-02-01

    International Commission on Radiological Protection (ICRP) Publication 103, 'The 2007 Recommendations of the International Commission on Radiological Protection', issued in 2007, defines emergency exposure situations as unexpected situations that may require the implementation of urgent protective actions and perhaps longer term protective actions. The ICRP continues to recommend optimisation and the use of reference levels to ensure an adequate degree of protection in regard to exposure to ionising radiation in emergency exposure situations. Reference levels represent the level of dose or risk above which it is judged to be inappropriate to plan to allow exposures to occur and for which protective actions should therefore be planned and optimised. National authorities are responsible for establishing reference levels. The Expert Group on the Implementation of New International Recommendations for Emergency Exposure Situations (EGIRES) performed a survey to analyse the established processes for optimisation of the protection strategy for emergency exposure situations and for practical implementation of the reference level concept in several member states of the Nuclear Energy Agency (NEA). The EGIRES collected information on several national optimisation strategy definitions, on optimisation of protection for different protective actions, and also on optimisation of urgent protective actions. In addition, national criteria for setting reference levels, their use, and relevant processes, including specific triggers and dosimetric quantifies in setting reference levels, are focus points that the EGIRES also evaluated. The analysis of national responses to this 2011 survey shows many differences in the interpretation and application of the established processes and suggests that most countries are still in the early stages of implementing these processes. Since 2011, national authorities have continued their study of the ICRP recommendations to incorporate them into

  17. 40 CFR 53.16 - Supersession of reference methods.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Supersession of reference methods. 53... (CONTINUED) AMBIENT AIR MONITORING REFERENCE AND EQUIVALENT METHODS General Provisions § 53.16 Supersession of reference methods. (a) This section prescribes procedures and criteria applicable to requests that...

  18. Radon measurements-discussion of error estimates for selected methods

    International Nuclear Information System (INIS)

    Zhukovsky, Michael; Onischenko, Alexandra; Bastrikov, Vladislav

    2010-01-01

    The main sources of uncertainties for grab sampling, short-term (charcoal canisters) and long term (track detectors) measurements are: systematic bias of reference equipment; random Poisson and non-Poisson errors during calibration; random Poisson and non-Poisson errors during measurements. The origins of non-Poisson random errors during calibration are different for different kinds of instrumental measurements. The main sources of uncertainties for retrospective measurements conducted by surface traps techniques can be divided in two groups: errors of surface 210 Pb ( 210 Po) activity measurements and uncertainties of transfer from 210 Pb surface activity in glass objects to average radon concentration during this object exposure. It's shown that total measurement error of surface trap retrospective technique can be decreased to 35%.

  19. Discussion on calculation method of overburden cover for radon reduction

    International Nuclear Information System (INIS)

    Liang Jianlong; Zhou Xinghuo; Zhou Ju; Liu Huijuan

    2010-01-01

    The article collects a large number of experimental results from domestic researchers with regard to soil overburden experimental methods. Based on analyzing experimental results, some questions in determining requirements for overburden cover thickness, data processing method and negative intercept have been dis- cussed. (authors)

  20. The Effect of Instructional Methods (Lecture-Discussion versus Group Discussion) and Teaching Talent on Teacher Trainees Student Learning Outcomes

    Science.gov (United States)

    Mutrofin; Degeng, Nyoman Sudana; Ardhana, Wayan; Setyosari, Punaji

    2017-01-01

    The aim of this study is to examine difference in the effect of instructional methods (lecture-discussion versus group discussion) and teaching talent on teacher trainees student learning outcomes. It was conducted by a quasi-experimental design using the factorialized (2 x 2) version of the nonequivalent control group design. The subjects were…

  1. Benchmarking routine psychological services: a discussion of challenges and methods.

    Science.gov (United States)

    Delgadillo, Jaime; McMillan, Dean; Leach, Chris; Lucock, Mike; Gilbody, Simon; Wood, Nick

    2014-01-01

    Policy developments in recent years have led to important changes in the level of access to evidence-based psychological treatments. Several methods have been used to investigate the effectiveness of these treatments in routine care, with different approaches to outcome definition and data analysis. To present a review of challenges and methods for the evaluation of evidence-based treatments delivered in routine mental healthcare. This is followed by a case example of a benchmarking method applied in primary care. High, average and poor performance benchmarks were calculated through a meta-analysis of published data from services working under the Improving Access to Psychological Therapies (IAPT) Programme in England. Pre-post treatment effect sizes (ES) and confidence intervals were estimated to illustrate a benchmarking method enabling services to evaluate routine clinical outcomes. High, average and poor performance ES for routine IAPT services were estimated to be 0.91, 0.73 and 0.46 for depression (using PHQ-9) and 1.02, 0.78 and 0.52 for anxiety (using GAD-7). Data from one specific IAPT service exemplify how to evaluate and contextualize routine clinical performance against these benchmarks. The main contribution of this report is to summarize key recommendations for the selection of an adequate set of psychometric measures, the operational definition of outcomes, and the statistical evaluation of clinical performance. A benchmarking method is also presented, which may enable a robust evaluation of clinical performance against national benchmarks. Some limitations concerned significant heterogeneity among data sources, and wide variations in ES and data completeness.

  2. Discussion on verification criterion and method of human factors engineering for nuclear power plant controller

    International Nuclear Information System (INIS)

    Yang Hualong; Liu Yanzi; Jia Ming; Huang Weijun

    2014-01-01

    In order to prevent or reduce human error and ensure the safe operation of nuclear power plants, control device should be verified from the perspective of human factors engineering (HFE). The domestic and international human factors engineering guidelines about nuclear power plant controller were considered, the verification criterion and method of human factors engineering for nuclear power plant controller were discussed and the application examples were provided for reference in this paper. The results show that the appropriate verification criterion and method should be selected to ensure the objectivity and accuracy of the conclusion. (authors)

  3. Method discussion of the performance evaluation on nuclear plant cable

    International Nuclear Information System (INIS)

    Lu Yongfang; Zhong Weixia; Sun Jiansheng; Liu Jingping

    2014-01-01

    A stock cable, which is same as the nuclear plant cable in service, was treated by thermal aging. After that, the mechanical property, the flame retardant property, the anti-oxidation were measured, and relationships between them due to the thermal aging were established. By those analysis, evaluating the in-service cable performance in nuclear plant and calculating its remaining life. Furthermore, the feasibility of this method was disscussed. (authors)

  4. Environmental reference materials methods and case studies

    DEFF Research Database (Denmark)

    Schramm-Nielsen, Karina Edith

    1998-01-01

    . This study lasted 22 months as well. The samples were produced and stored according to a 2³ factorial design. The influences of storage temperature, UV radiation and ultra-filtration on the stability of NH4-N and total phosphorous have been investigated. A Youden plot method is suggested for the graphical....... The methods have been evaluated with regard to their robustness towards variations in the chemical analytical method and with regard to the number of times a significant out of control situation is indicated. The second study regards the stability of NH4-N and total phosphorous in autoclaved seawater samples...... with wastewater. The purpose was to improve ortho-phosphate (and total phosphorous) homogeneity. A procedure is suggested which includes freeze-drying and redissolving. All calculations have been performed in SAS® primarily by means of elementary procedures, analyses of variance procedures, SAS Insight and SAS...

  5. More than Method?: A Discussion of Paradigm Differences within Mixed Methods Research

    Science.gov (United States)

    Harrits, Gitte Sommer

    2011-01-01

    This article challenges the idea that mixed methods research (MMR) constitutes a coherent research paradigm and explores how different research paradigms exist within MMR. Tracing paradigmatic differences at the level of methods, ontology, and epistemology, two MMR strategies are discussed: nested analysis, recently presented by the American…

  6. Reference depth for geostrophic computation - A new method

    Digital Repository Service at National Institute of Oceanography (India)

    Varkey, M.J.; Sastry, J.S.

    Various methods are available for the determination of reference depth for geostrophic computation. A new method based on the vertical profiles of mean and variance of the differences of mean specific volume anomaly (delta x 10) for different layers...

  7. Historical sketches of Sandia National Laboratories nuclear field testing. Volume 1: Full discussion except for sensitive references

    International Nuclear Information System (INIS)

    Banister, J.R.

    1994-10-01

    This report contains historical sketches that cover the major activities of Sandia nuclear field testing, from early atmospheric shots until 1990. It includes a chronological overview followed by more complete discussions of atmospheric, high-altitude, underwater, cratering, and underground nuclear testing. Other activities related to nuclear testing and high-explosive tests are also described. A large number of references are cited for readers who wish to learn more about technical details. Appendices, written by several authors, provide more insight for a variety of special aspects of nuclear testing and related work. Two versions of this history were published: volume 1 has an unlimited distribution, and volume 2 has a limited distribution

  8. Improving Reference Service: The Case for Using a Continuous Quality Improvement Method.

    Science.gov (United States)

    Aluri, Rao

    1993-01-01

    Discusses the evaluation of library reference service; examines problems with past evaluations, including the lack of long-term planning and a systems perspective; and suggests a method for continuously monitoring and improving reference service using quality improvement tools such as checklists, cause and effect diagrams, Pareto charts, and…

  9. Indirect methods for reference interval determination - review and recommendations.

    Science.gov (United States)

    Jones, Graham R D; Haeckel, Rainer; Loh, Tze Ping; Sikaris, Ken; Streichert, Thomas; Katayev, Alex; Barth, Julian H; Ozarda, Yesim

    2018-04-19

    Reference intervals are a vital part of the information supplied by clinical laboratories to support interpretation of numerical pathology results such as are produced in clinical chemistry and hematology laboratories. The traditional method for establishing reference intervals, known as the direct approach, is based on collecting samples from members of a preselected reference population, making the measurements and then determining the intervals. An alternative approach is to perform analysis of results generated as part of routine pathology testing and using appropriate statistical techniques to determine reference intervals. This is known as the indirect approach. This paper from a working group of the International Federation of Clinical Chemistry (IFCC) Committee on Reference Intervals and Decision Limits (C-RIDL) aims to summarize current thinking on indirect approaches to reference intervals. The indirect approach has some major potential advantages compared with direct methods. The processes are faster, cheaper and do not involve patient inconvenience, discomfort or the risks associated with generating new patient health information. Indirect methods also use the same preanalytical and analytical techniques used for patient management and can provide very large numbers for assessment. Limitations to the indirect methods include possible effects of diseased subpopulations on the derived interval. The IFCC C-RIDL aims to encourage the use of indirect methods to establish and verify reference intervals, to promote publication of such intervals with clear explanation of the process used and also to support the development of improved statistical techniques for these studies.

  10. Reference interval computation: which method (not) to choose?

    Science.gov (United States)

    Pavlov, Igor Y; Wilson, Andrew R; Delgado, Julio C

    2012-07-11

    When different methods are applied to reference interval (RI) calculation the results can sometimes be substantially different, especially for small reference groups. If there are no reliable RI data available, there is no way to confirm which method generates results closest to the true RI. We randomly drawn samples obtained from a public database for 33 markers. For each sample, RIs were calculated by bootstrapping, parametric, and Box-Cox transformed parametric methods. Results were compared to the values of the population RI. For approximately half of the 33 markers, results of all 3 methods were within 3% of the true reference value. For other markers, parametric results were either unavailable or deviated considerably from the true values. The transformed parametric method was more accurate than bootstrapping for sample size of 60, very close to bootstrapping for sample size 120, but in some cases unavailable. We recommend against using parametric calculations to determine RIs. The transformed parametric method utilizing Box-Cox transformation would be preferable way of RI calculation, if it satisfies normality test. If not, the bootstrapping is always available, and is almost as accurate and precise as the transformed parametric method. Copyright © 2012 Elsevier B.V. All rights reserved.

  11. MOISTURE IN COTTON BY THE KARL FISCHER TITRATION REFERENCE METHOD

    Science.gov (United States)

    Moisture is a critical parameter that influences many aspects of cotton fiber from harvesting and ginning to various fiber properties. Because of their importance, reference moisture methods that are more accurate than the existing oven-drying techniques and relatively easy to generate results are ...

  12. Does a Discussion by Any Other Name Sound the Same? Teaching Discussion in Three ELA Methods Courses

    Science.gov (United States)

    Alston, Chandra L.; Danielson, Katie A.; Dutro, Elizabeth; Cartun, Ashley

    2018-01-01

    Facilitating discussions in English Language Arts can develop students' skills as speakers and listeners and their ability to engage with diverse perspectives. However, classroom observations often demonstrate a lack of student talk, raising questions about the complexity of facilitating discussion and teachers' opportunities to learn and hone the…

  13. Certified reference materials and reference methods for nuclear safeguards and security.

    Science.gov (United States)

    Jakopič, R; Sturm, M; Kraiem, M; Richter, S; Aregbe, Y

    2013-11-01

    Confidence in comparability and reliability of measurement results in nuclear material and environmental sample analysis are established via certified reference materials (CRMs), reference measurements, and inter-laboratory comparisons (ILCs). Increased needs for quality control tools in proliferation resistance, environmental sample analysis, development of measurement capabilities over the years and progress in modern analytical techniques are the main reasons for the development of new reference materials and reference methods for nuclear safeguards and security. The Institute for Reference Materials and Measurements (IRMM) prepares and certifices large quantities of the so-called "large-sized dried" (LSD) spikes for accurate measurement of the uranium and plutonium content in dissolved nuclear fuel solutions by isotope dilution mass spectrometry (IDMS) and also develops particle reference materials applied for the detection of nuclear signatures in environmental samples. IRMM is currently replacing some of its exhausted stocks of CRMs with new ones whose specifications are up-to-date and tailored for the demands of modern analytical techniques. Some of the existing materials will be re-measured to improve the uncertainties associated with their certified values, and to enable laboratories to reduce their combined measurement uncertainty. Safeguards involve the quantitative verification by independent measurements so that no nuclear material is diverted from its intended peaceful use. Safeguards authorities pay particular attention to plutonium and the uranium isotope (235)U, indicating the so-called 'enrichment', in nuclear material and in environmental samples. In addition to the verification of the major ratios, n((235)U)/n((238)U) and n((240)Pu)/n((239)Pu), the minor ratios of the less abundant uranium and plutonium isotopes contain valuable information about the origin and the 'history' of material used for commercial or possibly clandestine purposes, and

  14. Dual reference point temperature interrogating method for distributed temperature sensor

    International Nuclear Information System (INIS)

    Ma, Xin; Ju, Fang; Chang, Jun; Wang, Weijie; Wang, Zongliang

    2013-01-01

    A novel method based on dual temperature reference points is presented to interrogate the temperature in a distributed temperature sensing (DTS) system. This new method is suitable to overcome deficiencies due to the impact of DC offsets and the gain difference in the two signal channels of the sensing system during temperature interrogation. Moreover, this method can in most cases avoid the need to calibrate the gain and DC offsets in the receiver, data acquisition and conversion. An improved temperature interrogation formula is presented and the experimental results show that this method can efficiently estimate the channel amplification and system DC offset, thus improving the system accuracy. (letter)

  15. EPA flow reference method testing and analysis: Findings report

    International Nuclear Information System (INIS)

    1999-06-01

    This report describes an experimental program sponsored by the US Environmental Protection Agency (EPA) to evaluate potential improvements to the Agency's current reference method for measuring volumetric flow (Method 2, 40 CFR Part 60, Appendix B). Method 2 (Determination of Stack Gas Velocity and Volumetric Flow Rate (Type S Pitot Tube)) specifies measurements to determine volumetric flow, but does not prescribe specific procedures to account for yaw or pitch angles of flow when the flow in the stack is not axial. Method 2 also allows the use of only two probe types, the Type S and the Prandtl

  16. Discussion of the Method to Determine the Ultimate Bearing Capacity of Soil Foundation

    Science.gov (United States)

    Du, Peng; Liu, Xiaoling; Zhang, Yangfu

    2017-12-01

    Combining literature examples, this paper has carried out Contrastive analysis of the theoretical formula method and finite element method about the ultimate bearing capacity of foundation, To verify rationality and superiority of the incremental load method in finite element ABAQUS in solving the bearing capacity of foundation soil. The study can provide certain reference for practical engineering calculation and analysis of foundation bearing capacity.

  17. Method of evaluation of diagnostics reference levels in computerized tomography

    International Nuclear Information System (INIS)

    Vega, Walter Flores

    1999-04-01

    Computerized tomography is a complex technique with several selectable exposition parameters delivering high doses to the patient. In this work it was developed a simple methodology to evaluate diagnostic reference levels in computerized tomography, using the concept of Multiple Scan Average Dose (MSAD), recently adopted by the Health Ministry. For evaluation of the MSAD, a dose distribution was obtained through a measured dose profile on the axial axis of a water phantom with thermoluminescence dosemeters, TLD-100, for different exam technique. The MSAD was evaluated hrough two distinct methods. First, it was evaluated by the integration of the dose profile of a single slice and, second, obtained by the integration on central slice of the profile of several slices. The latter is in of accordance with the ionization chamber method, suggesting to be the most practical method of dose evaluation to be applied in the diagnostic reference level assessment routine for CT, using TLDs. (author)

  18. Methods to explain emission trends. From reference to realization

    International Nuclear Information System (INIS)

    Gijsen, A.; Oude Lohuis, J.

    2003-01-01

    Several methods are available to assess and determine the effects of policy measures. In this article methods to determine the effects of social and political developments on the emission of CO2 from the production of electricity in the Netherlands are discussed [nl

  19. Reference neutron radiations. Part 1: Characteristics and methods of production

    International Nuclear Information System (INIS)

    2001-01-01

    ISO 8529 consists of the following parts, under the general title Reference neutron radiations: Part 1: Characteristics and methods of production; Part 2: Calibration fundamentals of radiation protection devices related to the basic quantities characterizing the radiation field; Part 3: Calibration of area and personal dosimeters and determination of response as a function of energy and angle of incidence. This Part 1. of ISO 8529 specifies the reference neutron radiations, in the energy range from thermal up to 20 MeV, for calibrating neutron-measuring devices used for radiation protection purposes and for determining their response as a function of neutron energy. Reference radiations are given for neutron fluence rates of up to 1x10 9 m 2 s-1 , corresponding, at a neutron energy of 1 MeV, to dose-equivalent rates of up to 100 mSv h -1 . This part of ISO 8529 is concerned only with the methods of producing and characterizing the neutron reference radiations. The procedures for applying these radiations for calibrations are described in ISO 8529-2 and ISO 8529-3. The reference radiations specified are the following: neutrons from radionuclide sources, including neutrons from sources in a moderator; neutrons produced by nuclear reactions with charged particles from accelerators; neutrons from reactors. In view of the methods of production and use of them, these reference radiations are divided, for the purposes of this part of ISO 8529, into the following two separate sections. In clause 4, radionuclide neutron sources with wide spectra are specified for the calibration of neutron measuring devices. These sources should be used by laboratories engaged in the routine calibration of neutron-measuring devices, the particular design of which has already been type tested. In clause 5, accelerator-produced monoenergetic neutrons and reactor-produced neutrons with wide or quasi monoenergetic spectra are specified for determining the response of neutron-measuring devices

  20. The discussion on the qualitative and quantitative evaluation methods for safety culture

    International Nuclear Information System (INIS)

    Gao Kefu

    2005-01-01

    The fundamental methods for safely culture evaluation are described. Combining with the practice of the quantitative evaluation of safety culture in Daya Bay NPP, the quantitative evaluation method for safety culture are discussed. (author)

  1. Reference material for trace analysis by radioanalytical methods: Bowen's Kale

    International Nuclear Information System (INIS)

    Wainerdi, R.E.

    1979-01-01

    A fairly large volume of published data on 'Bowen's Kale' has been examined critically in order to develop recommendations for the use of this preparation as a 'reference material' in the standardisation and evaluation of the reliability of analytical procedures. Values are now recommended for the contents of twelve elements present in major to trace concentrations in 'Bowen's Kale'. 'Indicated values' for another 16 elements are provided. Values for 15 more elements are listed with no recommendation. The criteria adopted in categorising elements into these groups are discussed. (author)

  2. Towards Automatic Testing of Reference Point Based Interactive Methods

    OpenAIRE

    Ojalehto, Vesa; Podkopaev, Dmitry; Miettinen, Kaisa

    2016-01-01

    In order to understand strengths and weaknesses of optimization algorithms, it is important to have access to different types of test problems, well defined performance indicators and analysis tools. Such tools are widely available for testing evolutionary multiobjective optimization algorithms. To our knowledge, there do not exist tools for analyzing the performance of interactive multiobjective optimization methods based on the reference point approach to communicating ...

  3. One directional polarized neutron reflectometry with optimized reference layer method

    International Nuclear Information System (INIS)

    Masoudi, S. Farhad; Jahromi, Saeed S.

    2012-01-01

    In the past decade, several neutron reflectometry methods for determining the modulus and phase of the complex reflection coefficient of an unknown multilayer thin film have been worked out among which the method of variation of surroundings and reference layers are of highest interest. These methods were later modified for measurement of the polarization of the reflected beam instead of the measurement of the intensities. In their new architecture, these methods not only suffered from the necessity of change of experimental setup but also another difficulty was added to their experimental implementations. This deficiency was related to the limitations of the technology of the neutron reflectometers that could only measure the polarization of the reflected neutrons in the same direction as the polarization of the incident beam. As the instruments are limited, the theory has to be optimized so that the experiment could be performed. In a recent work, we developed the method of variation of surroundings for one directional polarization analysis. In this new work, the method of reference layer with polarization analysis has been optimized to determine the phase and modulus of the unknown film with measurement of the polarization of the reflected neutrons in the same direction as the polarization of the incident beam.

  4. Methods to estimate irrigated reference crop evapotranspiration - a review.

    Science.gov (United States)

    Kumar, R; Jat, M K; Shankar, V

    2012-01-01

    Efficient water management of crops requires accurate irrigation scheduling which, in turn, requires the accurate measurement of crop water requirement. Irrigation is applied to replenish depleted moisture for optimum plant growth. Reference evapotranspiration plays an important role for the determination of water requirements for crops and irrigation scheduling. Various models/approaches varying from empirical to physically base distributed are available for the estimation of reference evapotranspiration. Mathematical models are useful tools to estimate the evapotranspiration and water requirement of crops, which is essential information required to design or choose best water management practices. In this paper the most commonly used models/approaches, which are suitable for the estimation of daily water requirement for agricultural crops grown in different agro-climatic regions, are reviewed. Further, an effort has been made to compare the accuracy of various widely used methods under different climatic conditions.

  5. Comparison of the reference mark azimuth determination methods

    Directory of Open Access Journals (Sweden)

    Danijel Šugar

    2013-03-01

    Full Text Available The knowledge of the azimuth of the reference mark is of crucial importance in the determination of the declination which is defined as the ellipsoidal (geodetic azimuth of the geomagnetic meridian. The accuracy of the azimuth determination has direct impact on the accuracy of the declination. The orientation of the Declination-Inclination Magnetometer is usually carried out by sighting the reference mark in two telescope faces in order to improve the reliability of the observations and eliminate some instrumental errors. In this paper, different coordinate as well as azimuth determination methods using GNSS (Global Navigation Satellite System observation techniques within VPPS (High-Precision Positioning Service and GPPS (Geodetic-Precision Positioning Service services of the CROPOS (CROatian POsitioning System system were explained. The azimuth determination by the observation of the Polaris was exposed and it was subsequently compared with the observation of the Sun using hour-angle and zenith-distance method. The procedure of the calculation of the geodetic azimuth from the astronomic azimuth was explained. The azimuth results obtained by different methods were compared and the recommendations on the minimal distance between repeat station and azimuth mark were given. The results shown in this paper were based on the observations taken on the POKU_SV repeat station.

  6. Human Cloning: Let's Discuss It.

    Science.gov (United States)

    Taras, Loretta; Stavroulakis, Anthea M.; Ortiz, Mary T.

    1999-01-01

    Describes experiences with holding discussions on cloning at a variety of levels in undergraduate biology courses. Discusses teaching methods used and student reactions to the discussions. Contains 12 references. (WRM)

  7. Generating method-specific Reference Ranges - A harmonious outcome?

    Science.gov (United States)

    Lee, Graham R; Griffin, Alison; Halton, Kieran; Fitzgibbon, Maria C

    2017-12-01

    When laboratory Reference Ranges (RR) do not reflect analytical methodology, result interpretation can cause misclassification of patients and inappropriate management. This can be mitigated by determining and implementing method-specific RRs, which was the main objective of this study. Serum was obtained from healthy volunteers (Male + Female, n > 120) attending hospital health-check sessions during June and July 2011. Pseudo-anonymised aliquots were stored (at - 70 °C) prior t° analysis on Abbott ARCHITECT c16000 chemistry and i 2000SR immunoassay analysers. Data were stratified by gender where appropriate. Outliers were excluded statistically (Tukey method) to generate non-parametric RRs (2.5th + 97.5th percentiles). RRs were compared to those quoted by Abbott and UK Pathology Harmony (PH) where possible. For 7 selected tests, RRs were verified using a data mining approach. For chemistry tests (n = 23), Upper or Lower Reference Limits (LRL or URL) were > 20% different from Abbott ranges in 25% of tests (11% from PH ranges) but in 38% for immunoassay tests (n = 13). RRs (mmol/L) for sodium (138-144), potassium (3.8-4.9) and chloride (102-110) were considerably narrower than PH ranges (133-146, 3.5-5.0 and 95-108, respectively). The gender difference for ferritin (M: 29-441, F: 8-193 ng/mL) was more pronounced than reported by Abbott (M: 22-275, F: 5-204 ng/mL). Verification studies showed good agreement for chemistry tests (mean [SD] difference = 0.4% [1.2%]) but less so for immunoassay tests (27% [29%]), particularly for TSH (LRL). Where resource permits, we advocate using method-specific RRs in preference to other sources, particularly where method bias and lack of standardisation limits RR transferability and harmonisation.

  8. Striking against bioterrorism with advanced proteomics and reference methods.

    Science.gov (United States)

    Armengaud, Jean

    2017-01-01

    The intentional use by terrorists of biological toxins as weapons has been of great concern for many years. Among the numerous toxins produced by plants, animals, algae, fungi, and bacteria, ricin is one of the most scrutinized by the media because it has already been used in biocrimes and acts of bioterrorism. Improving the analytical toolbox of national authorities to monitor these potential bioweapons all at once is of the utmost interest. MS/MS allows their absolute quantitation and exhibits advantageous sensitivity, discriminative power, multiplexing possibilities, and speed. In this issue of Proteomics, Gilquin et al. (Proteomics 2017, 17, 1600357) present a robust multiplex assay to quantify a set of eight toxins in the presence of a complex food matrix. This MS/MS reference method is based on scheduled SRM and high-quality standards consisting of isotopically labeled versions of these toxins. Their results demonstrate robust reliability based on rather loose scheduling of SRM transitions and good sensitivity for the eight toxins, lower than their oral median lethal doses. In the face of an increased threat from terrorism, relevant reference assays based on advanced proteomics and high-quality companion toxin standards are reliable and firm answers. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. Marine Biotoxins: Occurrence, Toxicity, Regulatory Limits and Reference Methods

    Directory of Open Access Journals (Sweden)

    Pierina Visciano

    2016-07-01

    Full Text Available Harmful algal blooms are natural phenomena caused by the massive growth of phytoplankton that may contain highly toxic chemicals, the so-called marine biotoxins causing illness and even death to both aquatic organisms and humans. Their occurrence has been increased in frequency and severity, suggesting a worldwide public health risk. Marine biotoxins can accumulate in bivalve molluscs and regulatory limits have been set for some classes according to European Union legislation. These compounds can be distinguished in water- and fat-soluble molecules. The first group involves those of Paralytic Shellfish Poisoning and Amnesic Shellfish Poisoning, whereas the toxins soluble in fat can cause Diarrheic Shellfish Poisoning and Neurotoxic Shellfish Poisoning. Due to the lack of long-term toxicity studies, establishing tolerable daily intakes for any of these marine biotoxins was not possible, but an acute reference dose can be considered more appropriate, because these molecules show an acute toxicity. Dietary exposure assessment is linked both to the levels of marine biotoxins present in bivalve molluscs and the portion that could be eaten by consumers. Symptoms may vary from a severe gastrointestinal intoxication with diarrhea, nausea, vomiting, and abdominal cramps to neurological disorders such as ataxia, dizziness, partial paralysis, and respiratory distress. The official method for the detection of marine biotoxins is the mouse bioassay (MBA showing some limits due to ethical restrictions and insufficient specificity. For this reason, the liquid chromatography–mass spectrometry method has replaced MBA as the reference technique. However, the monitoring of algal blooms producing marine biotoxins should be regularly assessed in order to obtain more reliable, accurate estimates of bloom toxicity and their potential impacts.

  10. Implementation of small group discussion as a teaching method in earth and space science subject

    Science.gov (United States)

    Aryani, N. P.; Supriyadi

    2018-03-01

    In Physics Department Universitas Negeri Semarang, Earth and Space Science subject is included in the curriculum of the third year of physics education students. There are various models of teaching earth and space science subject such as textbook method, lecturer, demonstrations, study tours, problem-solving method, etc. Lectures method is the most commonly used of teaching earth and space science subject. The disadvantage of this method is the lack of two ways interaction between lecturers and students. This research used small group discussion as a teaching method in Earth and Space science. The purpose of this study is to identify the conditions under which an efficient discussion may be initiated and maintained while students are investigating properties of earth and space science subjects. The results of this research show that there is an increase in student’s understanding of earth and space science subject proven through the evaluation results. In addition, during the learning process, student’s activeness also increase.

  11. Discussion on Boiler Efficiency Correction Method with Low Temperature Economizer-Air Heater System

    Science.gov (United States)

    Ke, Liu; Xing-sen, Yang; Fan-jun, Hou; Zhi-hong, Hu

    2017-05-01

    This paper pointed out that it is wrong to take the outlet flue gas temperature of low temperature economizer as exhaust gas temperature in boiler efficiency calculation based on GB10184-1988. What’s more, this paper proposed a new correction method, which decomposed low temperature economizer-air heater system into two hypothetical parts of air preheater and pre condensed water heater and take the outlet equivalent gas temperature of air preheater as exhaust gas temperature in boiler efficiency calculation. This method makes the boiler efficiency calculation more concise, with no air heater correction. It has a positive reference value to deal with this kind of problem correctly.

  12. Standard Test Method for Calibration of Non-Concentrator Photovoltaic Secondary Reference Cells

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2010-01-01

    1.1 This test method covers calibration and characterization of secondary terrestrial photovoltaic reference cells to a desired reference spectral irradiance distribution. The recommended physical requirements for these reference cells are described in Specification E1040. Reference cells are principally used in the determination of the electrical performance of a photovoltaic device. 1.2 Secondary reference cells are calibrated indoors using simulated sunlight or outdoors in natural sunlight by reference to a primary reference cell previously calibrated to the same desired reference spectral irradiance distribution. 1.3 Secondary reference cells calibrated according to this test method will have the same radiometric traceability as the of the primary reference cell used for the calibration. Therefore, if the primary reference cell is traceable to the World Radiometric Reference (WRR, see Test Method E816), the resulting secondary reference cell will also be traceable to the WRR. 1.4 This test method appli...

  13. Discussion on the fusing methods for HR and CCD images of CBERS

    International Nuclear Information System (INIS)

    Gao Zhangsheng; Zhao Yingjun

    2010-01-01

    CBERS-02B multi-spectral CCD data are different from HR panchromatic data in resolution, which causes difficulty in image fusion. With the method of Pansharping, HPF, Brovey transform, IHS transform, principal component transform, Gram Schmidt (GS) transform and wavelet transform, the authors have tested the fusion methods for CCD data and HR data of CBERS, and the fusion results are discussed and evaluated qualitatively and quantitatively. (authors)

  14. Discussion of the experimental methods of the estimation of the reaction impact parameter

    International Nuclear Information System (INIS)

    Muryn, B.; Dziunikowska, K.; Eskreys, A.; Coghen, T.

    1978-01-01

    Two methods of determination of the reaction impact parameter, the one proposed by Webber and other by Henyey and Pumplin, are compared and discussed. It is shown that the lower limits of the impact parameter bsub(L) obtained by means of these methods are comparable and are always very low (approximately < 0.5 fm). On the example of the Henyey - Pumplin method it is argued that the experimentally obtained values bsub(L) may be very unreliable estimates of the reaction impact parameter and that any comparison of different reactions or reactions channels may be meaningless. (author)

  15. Using mixed methods research designs in health psychology: an illustrated discussion from a pragmatist perspective.

    Science.gov (United States)

    Bishop, Felicity L

    2015-02-01

    To outline some of the challenges of mixed methods research and illustrate how they can be addressed in health psychology research. This study critically reflects on the author's previously published mixed methods research and discusses the philosophical and technical challenges of mixed methods, grounding the discussion in a brief review of methodological literature. Mixed methods research is characterized as having philosophical and technical challenges; the former can be addressed by drawing on pragmatism, the latter by considering formal mixed methods research designs proposed in a number of design typologies. There are important differences among the design typologies which provide diverse examples of designs that health psychologists can adapt for their own mixed methods research. There are also similarities; in particular, many typologies explicitly orient to the technical challenges of deciding on the respective timing of qualitative and quantitative methods and the relative emphasis placed on each method. Characteristics, strengths, and limitations of different sequential and concurrent designs are identified by reviewing five mixed methods projects each conducted for a different purpose. Adapting formal mixed methods designs can help health psychologists address the technical challenges of mixed methods research and identify the approach that best fits the research questions and purpose. This does not obfuscate the need to address philosophical challenges of mixing qualitative and quantitative methods. Statement of contribution What is already known on this subject? Mixed methods research poses philosophical and technical challenges. Pragmatism in a popular approach to the philosophical challenges while diverse typologies of mixed methods designs can help address the technical challenges. Examples of mixed methods research can be hard to locate when component studies from mixed methods projects are published separately. What does this study add? Critical

  16. LA-ICP-MS of magnetite: Methods and reference materials

    Science.gov (United States)

    Nadoll, P.; Koenig, A.E.

    2011-01-01

    Magnetite (Fe3O4) is a common accessory mineral in many geologic settings. Its variable geochemistry makes it a powerful petrogenetic indicator. Electron microprobe (EMPA) analyses are commonly used to examine major and minor element contents in magnetite. Laser ablation ICP-MS (LA-ICP-MS) is applicable to trace element analyses of magnetite but has not been widely employed to examine compositional variations. We tested the applicability of the NIST SRM 610, the USGS GSE-1G, and the NIST SRM 2782 reference materials (RMs) as external standards and developed a reliable method for LA-ICP-MS analysis of magnetite. LA-ICP-MS analyses were carried out on well characterized magnetite samples with a 193 nm, Excimer, ArF LA system. Although matrix-matched RMs are sometimes important for calibration and normalization of LA-ICP-MS data, we demonstrate that glass RMs can produce accurate results for LA-ICP-MS analyses of magnetite. Cross-comparison between the NIST SRM 610 and USGS GSE-1G indicates good agreement for magnetite minor and trace element data calibrated with either of these RMs. Many elements show a sufficiently good match between the LA-ICP-MS and the EMPA data; for example, Ti and V show a close to linear relationship with correlation coefficients, R2 of 0.79 and 0.85 respectively. ?? 2011 The Royal Society of Chemistry.

  17. New reference materials improvement of methods of measurements

    International Nuclear Information System (INIS)

    Marchandise, H.

    1985-01-01

    The report summarizes the development of about 120 reference materials in a variety of fields (non ferrous metals, trace element analysis, food products, biomedical analysis, physical and technical properties of solid materials). The document also provides practical advice for trace element analyses, describes the principles followed for certifying reference materials and provides recommendations for their use

  18. Discussion on the methods for calculation release limits for low-level radioactive waste

    International Nuclear Information System (INIS)

    Cao Fengbo; Liu Xiaochao

    2012-01-01

    The release request for low-level radioactive waste are briefly described in this paper. Associating with the conditions of low-level radioactive waste of some radioactive waste processing station, the methods and gist for calculating release limits for low-level radioactive waste with national release limits and annual effective dose limit for the public or the occupation are discussed. Then release limits for the low-level radioactive waste are also proposed. (authors)

  19. Discussion of the Investigation Method on the Reaction Kinetics of Metallurgical Reaction Engineering

    Science.gov (United States)

    Du, Ruiling; Wu, Keng; Zhang, Jiazhi; Zhao, Yong

    Reaction kinetics of metallurgical physical chemistry which was successfully applied in metallurgy (as ferrous metallurgy, non-ferrous metallurgy) became an important theoretical foundation for subject system of traditional metallurgy. Not only the research methods were very perfect, but also the independent structures and systems of it had been formed. One of the important tasks of metallurgical reaction engineering was the simulation of metallurgical process. And then, the mechanism of reaction process and the conversion time points of different control links should be obtained accurately. Therefore, the research methods and results of reaction kinetics in metallurgical physical chemistry were not very suitable for metallurgical reaction engineering. In order to provide the definite conditions of transmission, reaction kinetics parameters and the conversion time points of different control links for solving the transmission and reaction equations in metallurgical reaction engineering, a new method for researching kinetics mechanisms in metallurgical reaction engineering was proposed, which was named stepwise attempt method. Then the comparison of results between the two methods and the further development of stepwise attempt method were discussed in this paper. As a new research method for reaction kinetics in metallurgical reaction engineering, stepwise attempt method could not only satisfy the development of metallurgical reaction engineering, but also provide necessary guarantees for establishing its independent subject system.

  20. Advantages of discussion and cognitive conflict as an instructional method in contemporary teaching of mathematics

    Directory of Open Access Journals (Sweden)

    Mišurac-Zorica Irena

    2012-01-01

    Full Text Available Contemporary theories of teaching and learning mathematics emphasise the importance of learner’s active participation in the teaching process, in which discovery and logical reasoning lead to the construction of student’s knowledge. In this form of teaching, it is important to detect students’ misunderstandings and errors that can occur during learning. Uncovered tacit and false conceptions of students’ knowledge can greatly contribute to the opposite effect in the construction of knowledge. In teaching mathematics, there are many situations which leave students with ambiguities and misunderstandings, and create an impression in children that teaching of mathematics and mathematical knowledge itself is something that is not possible. Discussion and cognitive conflict are methods which have their starting point in the theory of constructivism. The aim of our study has been to determine whether application of the method of discussion and cognitive conflict in learning to divide decimal numbers leads to the enhancement of student’s procedural knowledge and conceptual knowledge about the division of decimal numbers. Longitudinally, we monitored two groups of 117 pupils of the fifth grade. In the first group, which was taught according to the guidelines of contemporary mathematics education, students engaged in discussion, discovering their misunderstandings and errors, and the cognitive conflict resulted in correct concepts. The second group of students were taught traditionally, learning the procedure and then practicing it. The paper presents a descriptive analysis of the process of teaching and quantitative analysis of the performance based on the comparison of conceptual and procedural knowledge of both groups. Results of our work show that the application of contemporary methods of discussion and cognitive conflict affects the increase of procedural and conceptual knowledge of the division of decimal numbers.

  1. The discussion of method for survey the radiosensitivity of human glioma cell line SHG-44

    International Nuclear Information System (INIS)

    Li Li; Xu Changshao; Zhou Juying; Xu Xiaoting; Luo Jialin

    2005-01-01

    Objective: To investigate if thiazolyl blue colorimetric assay (MTT) and cell counting kit-8 (CCK-8) can replace clone forming assay for survey the radiosensitivity of SHG-44. Methods; Three assays was applied to examine the growth inhibition of human glioma cell line SHG-44 in eight dose groups of 0, 1, 2, 3, 4, 6, 8 and 10 Gy, and statistical research was applied to analyze the correlation between survival fraction and various doses. Results: Dose was associated with survival fraction in these three assays at some range of irradiation doseage (dose≤3 Gy). If out of the range, the relation is poor. CCK-8 has no rather superiority than MTT. Conclusion: By now clone forming assay is still the 'gold standard'. In some cases, MTT and other assays can give us some reference, but these assays still can not replace clone forming assay. (authors)

  2. Discussion method for the Wigner-Seitz model applied to plane problems; Methode de discussion du modele Wigner-Seitz appliquee a des problemes plans

    Energy Technology Data Exchange (ETDEWEB)

    Winter, J

    1949-04-01

    This report discusses the approximation which consists, for the study of a waves field, in replacing a square domain by a circular domain in a square orthogonal mesh network. For this purpose, it is proposed to introduce J{sub 4}(Kr)cos(4{theta}) and Y{sub 4}(Kr)cos(4{theta}) terms and to modify the outside limits of the mesh for the calculation of the coefficients of these terms.

  3. A preliminary verification of the floating reference measurement method for non-invasive blood glucose sensing

    Science.gov (United States)

    Min, Xiaolin; Liu, Rong; Fu, Bo; Xu, Kexin

    2017-06-01

    In the non-invasive sensing of blood glucose by near-infrared diffuse reflectance spectroscopy, the spectrum is highly susceptible to the unstable and complicated background variations from the human body and the environment. In in vitro analyses, background variations are usually corrected by the spectrum of a standard reference sample that has similar optical properties to the analyte of interest. However, it is hard to find a standard sample for the in vivo measurement. Therefore, the floating reference measurement method is proposed to enable relative measurements in vivo, where the spectra under some special source-detector distance, defined as the floating reference position, are insensitive to the changes in glucose concentration due to the absorption effect and scattering effect. Because the diffuse reflectance signals at the floating reference positions only reflect the information on background variations during the measurement, they can be used as the internal reference. In this paper, the theoretical basis of the floating reference positions in a semi-infinite turbid medium was discussed based on the steady-state diffusion equation and its analytical solutions in a semi-infinite turbid medium (under the extrapolated boundary conditions). Then, Monte-Carlo (MC) simulations and in vitro experiments based on a custom-built continuous-moving spatially resolving double-fiber NIR measurement system, configured with two types of light source, a super luminescent diode (SLD) and a super-continuum laser, were carried out to verify the existence of the floating reference position in 5%, 10% and 20% Intralipid solutions. The results showed that the simulation values of the floating reference positions are close to the theoretical results, with a maximum deviation of approximately 0.3 mm in 1100-1320 nm. Great differences can be observed in 1340-1400 nm because the optical properties of Intralipid in this region don not satisfy the conditions of the steady

  4. The Organic Food Method and Movement: An Interdisciplinary Reference Review

    Science.gov (United States)

    Park, Elizabeth E.

    2011-01-01

    From popular movies to New York Times bestsellers, organic food is widely acknowledged to be of growing importance. Many community college students are asking: How is organic food different from everything else in the grocery store? What impact does farming have on the environment? How safe is our food? A survey of reference works introduces…

  5. Discussion of a method for providing general risk information by linking with the nuclear information

    International Nuclear Information System (INIS)

    Shobu, Nobuhiro; Yokomizo, Shirou; Umezawa, Sayaka

    2004-06-01

    'Risk information navigator (http://www.ricotti.jp/risknavi/)', an internet tool for arousing public interest and fostering people's risk literacy, has been developed as the contents for the official website of Techno Community Square 'RICOTTI' (http://www.ricotti.jp) at TOKAI village. In this report we classified the risk information into the fields, Health/Daily Life', 'Society/Crime/Disaster' and Technology/Environment/Energy', for the internet tool contents. According to these categories we discussed a method for providing various risk information on general fields by linking with the information on nuclear field. The web contents are attached to this report with the CD-R media. (author)

  6. Comparison and discussion of two types of threat (Hazard) categorization method for nuclear facilities

    International Nuclear Information System (INIS)

    Tang, Rongyao; Xu, Xiaoxiao; Zhang, Jiangang; Zhao, Bin

    2008-01-01

    The emergency threat categorization method suggested by international atomic energy agency (IAEA) and hazard categorization standard by the Department of Energy of United States (USDOE) for nuclear facilities are compared and discussed in this paper. The research shows the two types of categorization method for nuclear facility are similar, though each has its own speciality. The categorization method suggested by IAEA is quite completed and sound in scientific basis. The thresholds of radioactive material are connected with the quantity of dangerous source, and the latest radiobiological effect research results are taken in setting the thresholds. While the main purpose is put on emergency management, some of the categorization criteria do not fit for safety surveillance of nuclear facilities. The categorization method of DOE is advanced in its operability, and it fits for safety surveillance. The disadvantage is that the thresholds of radioactive material need to be updated because the parameters used in calculation is outdated, and also the threshold of category 3 is somewhat disputable for many reasons. We should take advantage of both methods and adjust the standards according to the application purpose while establishing the categorization standard of nuclear facilities in China. (author)

  7. [Discussion on appraisal methods and key technologies of arbuscular mycorrhizal fungi and medicinal plant symbiosis system].

    Science.gov (United States)

    Chen, Meilan; Guo, Lanping; Yang, Guang; Chen, Min; Yang, Li; Huang, Luqi

    2011-11-01

    Applications of arbuscular mycorrhizal fungi in research of medicinal plant cultivation are increased in recent years. Medicinal plants habitat is complicated and many inclusions are in root, however crop habitat is simple and few inclusions in root. So appraisal methods and key technologies about the symbiotic system of crop and arbuscular mycorrhizal fungi can't completely suitable for the symbiotic system of medicinal plants and arbuscular mycorrhizal fungi. This article discuss the appraisal methods and key technologies about the symbiotic system of medicinal plant and arbuscular mycorrhizal fungi from the isolation and identification of arbuscular mycorrhiza, and the appraisal of colonization intensity. This article provides guidance for application research of arbuscular mycorrhizal fungi in cultivation of medicinal plants.

  8. Reference Values for Spirometry Derived Using Lambda, Mu, Sigma (LMS) Method in Korean Adults: in Comparison with Previous References.

    Science.gov (United States)

    Jo, Bum Seak; Myong, Jun Pyo; Rhee, Chin Kook; Yoon, Hyoung Kyu; Koo, Jung Wan; Kim, Hyoung Ryoul

    2018-01-15

    The present study aimed to update the prediction equations for spirometry and their lower limits of normal (LLN) by using the lambda, mu, sigma (LMS) method and to compare the outcomes with the values of previous spirometric reference equations. Spirometric data of 10,249 healthy non-smokers (8,776 females) were extracted from the fourth and fifth versions of the Korea National Health and Nutrition Examination Survey (KNHANES IV, 2007-2009; V, 2010-2012). Reference equations were derived using the LMS method which allows modeling skewness (lambda [L]), mean (mu [M]), and coefficient of variation (sigma [S]). The outcome equations were compared with previous reference values. Prediction equations were presented in the following form: predicted value = e{a + b × ln(height) + c × ln(age) + M - spline}. The new predicted values for spirometry and their LLN derived using the LMS method were shown to more accurately reflect transitions in pulmonary function in young adults than previous prediction equations derived using conventional regression analysis in 2013. There were partial discrepancies between the new reference values and the reference values from the Global Lung Function Initiative in 2012. The results should be interpreted with caution for young adults and elderly males, particularly in terms of the LLN for forced expiratory volume in one second/forced vital capacity in elderly males. Serial spirometry follow-up, together with correlations with other clinical findings, should be emphasized in evaluating the pulmonary function of individuals. Future studies are needed to improve the accuracy of reference data and to develop continuous reference values for spirometry across all ages. © 2018 The Korean Academy of Medical Sciences.

  9. A simple and effective method to achieve the successful start-up of a current reference

    International Nuclear Information System (INIS)

    Han Lei; Zhang Xiaoxing; Dai Yujie; Lü Yingjie; Wang Yujun

    2012-01-01

    Start-up design is a critical issue in current reference as it is very closely related to production yield. However, its function is difficult to predict using normal transaction simulations before the device is put into diffusion. In this paper, we discuss a simple and effective simulation approach which ensures a successful start-up process in a self-biased temperature independent current reference. The circuit is implemented in a class-D power amplifier with a 0.35 μm BiCMOS process and the experimental result validates that, by using this method, the start-up success rate can be greatly improved to 100%. (semiconductor integrated circuits)

  10. Discussion and a new method of optical cryptosystem based on interference

    Science.gov (United States)

    Lu, Dajiang; He, Wenqi; Liao, Meihua; Peng, Xiang

    2017-02-01

    A discussion and an objective security analysis of the well-known optical image encryption based on interference are presented in this paper. A new method is also proposed to eliminate the security risk of the original cryptosystem. For a possible practical application, we expand this new method into a hierarchical authentication scheme. In this authentication system, with a pre-generated and fixed random phase lock, different target images indicating different authentication levels are analytically encoded into corresponding phase-only masks (phase keys) and amplitude-only masks (amplitude keys). For the authentication process, a legal user can obtain a specified target image at the output plane if his/her phase key, and amplitude key, which should be settled close against the fixed internal phase lock, are respectively illuminated by two coherent beams. By comparing the target image with all the standard certification images in the database, the system can thus verify the user's legality even his/her identity level. Moreover, in despite of the internal phase lock of this system being fixed, the crosstalk between different pairs of keys held by different users is low. Theoretical analysis and numerical simulation are both provided to demonstrate the validity of this method.

  11. Text mining for search term development in systematic reviewing: A discussion of some methods and challenges.

    Science.gov (United States)

    Stansfield, Claire; O'Mara-Eves, Alison; Thomas, James

    2017-09-01

    Using text mining to aid the development of database search strings for topics described by diverse terminology has potential benefits for systematic reviews; however, methods and tools for accomplishing this are poorly covered in the research methods literature. We briefly review the literature on applications of text mining for search term development for systematic reviewing. We found that the tools can be used in 5 overarching ways: improving the precision of searches; identifying search terms to improve search sensitivity; aiding the translation of search strategies across databases; searching and screening within an integrated system; and developing objectively derived search strategies. Using a case study and selected examples, we then reflect on the utility of certain technologies (term frequency-inverse document frequency and Termine, term frequency, and clustering) in improving the precision and sensitivity of searches. Challenges in using these tools are discussed. The utility of these tools is influenced by the different capabilities of the tools, the way the tools are used, and the text that is analysed. Increased awareness of how the tools perform facilitates the further development of methods for their use in systematic reviews. Copyright © 2017 John Wiley & Sons, Ltd.

  12. GTX Reference Vehicle Structural Verification Methods and Weight Summary

    Science.gov (United States)

    Hunter, J. E.; McCurdy, D. R.; Dunn, P. W.

    2002-01-01

    The design of a single-stage-to-orbit air breathing propulsion system requires the simultaneous development of a reference launch vehicle in order to achieve the optimal mission performance. Accordingly, for the GTX study a 300-lb payload reference vehicle was preliminarily sized to a gross liftoff weight (GLOW) of 238,000 lb. A finite element model of the integrated vehicle/propulsion system was subjected to the trajectory environment and subsequently optimized for structural efficiency. This study involved the development of aerodynamic loads mapped to finite element models of the integrated system in order to assess vehicle margins of safety. Commercially available analysis codes were used in the process along with some internally developed spreadsheets and FORTRAN codes specific to the GTX geometry for mapping of thermal and pressure loads. A mass fraction of 0.20 for the integrated system dry weight has been the driver for a vehicle design consisting of state-of-the-art composite materials in order to meet the rigid weight requirements. This paper summarizes the methodology used for preliminary analyses and presents the current status of the weight optimization for the structural components of the integrated system.

  13. Reference satellite selection method for GNSS high-precision relative positioning

    Directory of Open Access Journals (Sweden)

    Xiao Gao

    2017-03-01

    Full Text Available Selecting the optimal reference satellite is an important component of high-precision relative positioning because the reference satellite directly influences the strength of the normal equation. The reference satellite selection methods based on elevation and positional dilution of precision (PDOP value were compared. Results show that all the above methods cannot select the optimal reference satellite. We introduce condition number of the design matrix in the reference satellite selection method to improve structure of the normal equation, because condition number can indicate the ill condition of the normal equation. The experimental results show that the new method can improve positioning accuracy and reliability in precise relative positioning.

  14. Research on Integrated Analysis Method for Equipment and Tactics Based on Intervention Strategy Discussion

    Institute of Scientific and Technical Information of China (English)

    陈超; 张迎新; 毛赤龙

    2012-01-01

    As the increase of the complexity of the information warfare,its intervention strategy needs to be designed in an integrated environment.However,the current research always breaks the internal relation between equipment and tactics,and it is difficult to meet the requirements of their integrated analysis.In this paper,the research status quo of the integrated analysis about equipment and tactics is discussed first,some shortages of the current methods are summarized then,and an evolvement mechanism of the integrated analysis for equipment and tactics is given finally.Based on these,a framework of integrated analysis is proposed.This method's effectiveness is validated by an example.

  15. Resampling Approach for Determination of the Method for Reference Interval Calculation in Clinical Laboratory Practice▿

    Science.gov (United States)

    Pavlov, Igor Y.; Wilson, Andrew R.; Delgado, Julio C.

    2010-01-01

    Reference intervals (RI) play a key role in clinical interpretation of laboratory test results. Numerous articles are devoted to analyzing and discussing various methods of RI determination. The two most widely used approaches are the parametric method, which assumes data normality, and a nonparametric, rank-based procedure. The decision about which method to use is usually made arbitrarily. The goal of this study was to demonstrate that using a resampling approach for the comparison of RI determination techniques could help researchers select the right procedure. Three methods of RI calculation—parametric, transformed parametric, and quantile-based bootstrapping—were applied to multiple random samples drawn from 81 values of complement factor B observations and from a computer-simulated normally distributed population. It was shown that differences in RI between legitimate methods could be up to 20% and even more. The transformed parametric method was found to be the best method for the calculation of RI of non-normally distributed factor B estimations, producing an unbiased RI and the lowest confidence limits and interquartile ranges. For a simulated Gaussian population, parametric calculations, as expected, were the best; quantile-based bootstrapping produced biased results at low sample sizes, and the transformed parametric method generated heavily biased RI. The resampling approach could help compare different RI calculation methods. An algorithm showing a resampling procedure for choosing the appropriate method for RI calculations is included. PMID:20554803

  16. A rule-based reference resolution method for Dutch discourse

    NARCIS (Netherlands)

    Harabagiu, S.; op den Akker, Hendrikus J.A.; Hospers, M.A.; Ferrandez, A.; Kroezen, Erna; Nijholt, Antinus; Lie, Danny

    2002-01-01

    This paper presents a knowledge-poor method for the solution of anaphoric and deictic expressions in Dutch texts. The method is developed for use in a text summarization system. Anaphora resolution plays an important role in the analysis of the original text as well as in the generation of the text

  17. A discussion on validity of the diffusion theory by Monte Carlo method

    Science.gov (United States)

    Peng, Dong-qing; Li, Hui; Xie, Shusen

    2008-12-01

    Diffusion theory was widely used as a basis of the experiments and methods in determining the optical properties of biological tissues. A simple analytical solution could be obtained easily from the diffusion equation after a series of approximations. Thus, a misinterpret of analytical solution would be made: while the effective attenuation coefficient of several semi-infinite bio-tissues were the same, the distribution of light fluence in the tissues would be the same. In order to assess the validity of knowledge above, depth resolved internal fluence of several semi-infinite biological tissues which have the same effective attenuation coefficient were simulated with wide collimated beam in the paper by using Monte Carlo method in different condition. Also, the influence of bio-tissue refractive index on the distribution of light fluence was discussed in detail. Our results showed that, when the refractive index of several bio-tissues which had the same effective attenuation coefficient were the same, the depth resolved internal fluence would be the same; otherwise, the depth resolved internal fluence would be not the same. The change of refractive index of tissue would have affection on the light depth distribution in tissue. Therefore, the refractive index is an important optical property of tissue, and should be taken in account while using the diffusion approximation theory.

  18. A brief discussion about image quality and SEM methods for quantitative fractography of polymer composites.

    Science.gov (United States)

    Hein, L R O; Campos, K A; Caltabiano, P C R O; Kostov, K G

    2013-01-01

    The methodology for fracture analysis of polymeric composites with scanning electron microscopes (SEM) is still under discussion. Many authors prefer to use sputter coating with a conductive material instead of applying low-voltage (LV) or variable-pressure (VP) methods, which preserves the original surfaces. The present work examines the effects of sputter coating with 25 nm of gold on the topography of carbon-epoxy composites fracture surfaces, using an atomic force microscope. Also, the influence of SEM imaging parameters on fractal measurements is evaluated for the VP-SEM and LV-SEM methods. It was observed that topographic measurements were not significantly affected by the gold coating at tested scale. Moreover, changes on SEM setup leads to nonlinear outcome on texture parameters, such as fractal dimension and entropy values. For VP-SEM or LV-SEM, fractal dimension and entropy values did not present any evident relation with image quality parameters, but the resolution must be optimized with imaging setup, accompanied by charge neutralization. © Wiley Periodicals, Inc.

  19. A global multicenter study on reference values: 1. Assessment of methods for derivation and comparison of reference intervals.

    Science.gov (United States)

    Ichihara, Kiyoshi; Ozarda, Yesim; Barth, Julian H; Klee, George; Qiu, Ling; Erasmus, Rajiv; Borai, Anwar; Evgina, Svetlana; Ashavaid, Tester; Khan, Dilshad; Schreier, Laura; Rolle, Reynan; Shimizu, Yoshihisa; Kimura, Shogo; Kawano, Reo; Armbruster, David; Mori, Kazuo; Yadav, Binod K

    2017-04-01

    The IFCC Committee on Reference Intervals and Decision Limits coordinated a global multicenter study on reference values (RVs) to explore rational and harmonizable procedures for derivation of reference intervals (RIs) and investigate the feasibility of sharing RIs through evaluation of sources of variation of RVs on a global scale. For the common protocol, rather lenient criteria for reference individuals were adopted to facilitate harmonized recruitment with planned use of the latent abnormal values exclusion (LAVE) method. As of July 2015, 12 countries had completed their study with total recruitment of 13,386 healthy adults. 25 analytes were measured chemically and 25 immunologically. A serum panel with assigned values was measured by all laboratories. RIs were derived by parametric and nonparametric methods. The effect of LAVE methods is prominent in analytes which reflect nutritional status, inflammation and muscular exertion, indicating that inappropriate results are frequent in any country. The validity of the parametric method was confirmed by the presence of analyte-specific distribution patterns and successful Gaussian transformation using the modified Box-Cox formula in all countries. After successful alignment of RVs based on the panel test results, nearly half the analytes showed variable degrees of between-country differences. This finding, however, requires confirmation after adjusting for BMI and other sources of variation. The results are reported in the second part of this paper. The collaborative study enabled us to evaluate rational methods for deriving RIs and comparing the RVs based on real-world datasets obtained in a harmonized manner. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  20. 40 CFR 75.22 - Reference test methods.

    Science.gov (United States)

    2010-07-01

    ... tester may also opt to use the sample recovery and preparation procedures in ASTM D6784-02 (incorporated... 75.22 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED... site and sample traverses. (2) Method 2 or its allowable alternatives, as provided in appendix A to...

  1. Automatically classifying sentences in full-text biomedical articles into Introduction, Methods, Results and Discussion.

    Science.gov (United States)

    Agarwal, Shashank; Yu, Hong

    2009-12-01

    Biomedical texts can be typically represented by four rhetorical categories: Introduction, Methods, Results and Discussion (IMRAD). Classifying sentences into these categories can benefit many other text-mining tasks. Although many studies have applied different approaches for automatically classifying sentences in MEDLINE abstracts into the IMRAD categories, few have explored the classification of sentences that appear in full-text biomedical articles. We first evaluated whether sentences in full-text biomedical articles could be reliably annotated into the IMRAD format and then explored different approaches for automatically classifying these sentences into the IMRAD categories. Our results show an overall annotation agreement of 82.14% with a Kappa score of 0.756. The best classification system is a multinomial naïve Bayes classifier trained on manually annotated data that achieved 91.95% accuracy and an average F-score of 91.55%, which is significantly higher than baseline systems. A web version of this system is available online at-http://wood.ims.uwm.edu/full_text_classifier/.

  2. Case Method Instruction: 25 Minutes of Discussion Can Make a Difference

    National Research Council Canada - National Science Library

    Zbylut, Michelle L; Brunner, Jason M; Vowels, Christopher L; Kim, Julia M

    2007-01-01

    .... Findings indicated that students produced better quality answers and were better able to diagnose leadership problems in the scenario after participating in discussion, even though the time allotted...

  3. Influence of adsorption and deproteination on potential free thyroxine reference methods

    DEFF Research Database (Denmark)

    Holm, Steen S; Andreasen, Lisbeth; Hansen, Palle Steen

    2002-01-01

    There is a need for consensus concerning reference methods to be used for calibration of commercial free-thyroxine (FT(4)) assays.......There is a need for consensus concerning reference methods to be used for calibration of commercial free-thyroxine (FT(4)) assays....

  4. Discussion of Science and Math Teaching Methods: criticism and possibilities in teaching practices

    Directory of Open Access Journals (Sweden)

    Elizabeth Gerhardt Manfredo

    2005-06-01

    Full Text Available This paper presents a discussion of practices among Science and Math teachers in Brazilian Basic Education. Analysis focuses on criticism over teaching practices throughout Basic Education which includes Children, Primary and Medium levels. Discussion highlights the interdisciplinary and educational projects as the most chosen tool for reflective practices. Most educational problems must be solved by the use of shared theoretical choices and investigative methodological approach. Such choices ought to be made during teachers' continuing trainning based on a researcher-teacher action as it provides ways for methodological changes in Sciences and Math Education in the Country

  5. Seismic risk maps of Switzerland; description of the probabilistic method and discussion of some input parameters

    International Nuclear Information System (INIS)

    Mayer-Rosa, D.; Merz, H.A.

    1976-01-01

    The probabilistic model used in a seismic risk mapping project for Switzerland is presented. Some of its advantages and limitations are spelled out. In addition some earthquake parameters which should be carefully investigated before using them in a seismic risk analysis are discussed

  6. Rapid issue tracking: A method for taking the pulse of the public discussion of environmental policy

    Science.gov (United States)

    David N. Bengston; David P. Fan; Patrick Reed; Ashley. Goldhor-Wilcock

    2009-01-01

    Environmental communication professionals and other decision makers need to understand public sentiment toward environmental issues to effectively carry out their stewardship responsibilities. However, it is often difficult to obtain timely and reliable information about public discussion and debate regarding these issues. This paper describes an approach designed to...

  7. SYSTEMATIC ERROR REDUCTION: NON-TILTED REFERENCE BEAM METHOD FOR LONG TRACE PROFILER

    International Nuclear Information System (INIS)

    QIAN, S.; QIAN, K.; HONG, Y.; SENG, L.; HO, T.; TAKACS, P.

    2007-01-01

    Systematic error in the Long Trace Profiler (LTP) has become the major error source as measurement accuracy enters the nanoradian and nanometer regime. Great efforts have been made to reduce the systematic error at a number of synchrotron radiation laboratories around the world. Generally, the LTP reference beam has to be tilted away from the optical axis in order to avoid fringe overlap between the sample and reference beams. However, a tilted reference beam will result in considerable systematic error due to optical system imperfections, which is difficult to correct. Six methods of implementing a non-tilted reference beam in the LTP are introduced: (1) application of an external precision angle device to measure and remove slide pitch error without a reference beam, (2) independent slide pitch test by use of not tilted reference beam, (3) non-tilted reference test combined with tilted sample, (4) penta-prism scanning mode without a reference beam correction, (5) non-tilted reference using a second optical head, and (6) alternate switching of data acquisition between the sample and reference beams. With a non-tilted reference method, the measurement accuracy can be improved significantly. Some measurement results are presented. Systematic error in the sample beam arm is not addressed in this paper and should be treated separately

  8. [Discussion on ideological concept implied in traditional reinforcing and reducing method of acupuncture].

    Science.gov (United States)

    Li, Suyun; Zhao, Jingsheng

    2017-11-12

    The forming and development of traditional reinforcing and reducing method of acupuncture was rooted in traditional culture of China, and was based on the ancients' special understanding of nature, life and diseases, therefore its principle and methods were inevitably influenced by philosophy culture and medicine concept at that time. With deep study on Inner Canon of Huangdi and representative reinforcing and reducing method of acupuncture, the implied ideological concept, including contradiction view and profit-loss view in ancient dialectic, yin-yang balance theory, concept of life flow, monophyletic theory of qi , theory of existence of disease-evil, yin - yang astrology theory, theory of inter-promotion of five elements, were summarized and analyzed. The clarified and systematic understanding on guiding ideology of reinforcing and reducing method of acupuncture could significantly promote the understanding on principle, method, content and manipulation.

  9. Discussion of various flow calculation methods in high-speed centrifuges

    International Nuclear Information System (INIS)

    Louvet, P.; Cortet, C.

    1979-01-01

    The flow in high-speed centrifuges for the separation of uranium isotopes has been studied in the frame of linearized theory for long years. Three different methods have been derived for viscous compressible flow with small Ekman numbers and high Mach numbers: - numerical solution of flow equation by finite element method and Gaussian elimination (Centaure Code), - boundary layer theory using matched asymptotic expansions, - the so called eigenfunction method slightly modified. The mathematical assumptions, the easiness and the accuracy of the computations are compared. Numerical applications are performed successively for thermal countercurrent centrifuges with or without injections

  10. The discussion of a method to determine the underground destruction range of nuclear earth penetrator bursts

    International Nuclear Information System (INIS)

    Geng Xiaobing; Zhang Zhongshan

    2007-01-01

    This thesis chooses cross hole seismic tomography to determine the destruction range of surrounded rock in virtue of the characteristic of nuclear earth penetrator explosion.According to Fermat's principle, ray tracing method-the shortest path method suggested by Moser used, a programme was produced to calculate seismic travel time and then to simulate the collection the practical travel time data. The Genetic Algorithm is adopted as the inversion method to simulate in accordance with the crater model of nuclear earth penetrator explosion. (authors)

  11. A New Synchronous Reference Frame-Based Method for Single-Phase Shunt Active Power Filters

    DEFF Research Database (Denmark)

    Monfared, Mohammad; Golestan, Saeed; Guerrero, Josep M.

    2013-01-01

    This paper deals with the design of a novel method in the synchronous reference frame (SRF) to extract the reference compensating current for single-phase shunt active power filters (APFs). Unlike previous works in the SRF, the proposed method has an innovative feature that it does not need...... the fictitious current signal. Frequency-independent operation, accurate reference current extraction and relatively fast transient response are other key features of the presented strategy. The effectiveness of the proposed method is investigated by means of detailed mathematical analysis. The results confirm...

  12. Preliminary discussion on the application of the geological conceptual model method of uranium ore formation

    International Nuclear Information System (INIS)

    Ma Guangzhong; Wei Mingji; Luo Yiyue

    1992-01-01

    The geological conceptual model method of uranium ore formation is established on the basis of geological theory and apriorism. Variables are screened with the application of the method of mathematical geology to find out the variables which are more contributed. In combination with the practical situation in Xikang-Yunnan axis, the variables are compiled and graded so as to determine the optimal ore-controlling factor and to establish the statistical predictive model which is of geological significance. The resources evaluation work has been conducted in the Late Proterozoic geological terrain in Xikang-Yunnan axis

  13. Brief Discussions of a Draw of American Universal Education on Chinese Postgraduate Teaching Methods

    Directory of Open Access Journals (Sweden)

    Li Zhengminqing

    2015-01-01

    Full Text Available Initiated by International Friendships Inc.(IFI in Cincinnati, that is a Christian community organization, the authors participated in a universal education activity, called “History Museum”, organized by the local people in Kentucky State of U.S.A. In the activity, the authors grasped some characteristics of American universal education and reflected some problems of the professional foundation teaching of Chinese postgraduates, especially of Chinese engineering postgraduates. Based on the above thinking, some suggestions of the teaching methods for the professional foundation courses of Chinese postgraduates are proposed. Furthermore, the authors hope the proposed methods would be good for improving the postgraduate education in China.

  14. Resampling methods in Microsoft Excel® for estimating reference intervals.

    Science.gov (United States)

    Theodorsson, Elvar

    2015-01-01

    Computer-intensive resampling/bootstrap methods are feasible when calculating reference intervals from non-Gaussian or small reference samples. Microsoft Excel® in version 2010 or later includes natural functions, which lend themselves well to this purpose including recommended interpolation procedures for estimating 2.5 and 97.5 percentiles. 
The purpose of this paper is to introduce the reader to resampling estimation techniques in general and in using Microsoft Excel® 2010 for the purpose of estimating reference intervals in particular.
 Parametric methods are preferable to resampling methods when the distributions of observations in the reference samples is Gaussian or can transformed to that distribution even when the number of reference samples is less than 120. Resampling methods are appropriate when the distribution of data from the reference samples is non-Gaussian and in case the number of reference individuals and corresponding samples are in the order of 40. At least 500-1000 random samples with replacement should be taken from the results of measurement of the reference samples.

  15. 7 CFR 801.7 - Reference methods and tolerances for near-infrared spectroscopy (NIRS) analyzers.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Reference methods and tolerances for near-infrared spectroscopy (NIRS) analyzers. 801.7 Section 801.7 Agriculture Regulations of the Department of Agriculture...), DEPARTMENT OF AGRICULTURE OFFICIAL PERFORMANCE REQUIREMENTS FOR GRAIN INSPECTION EQUIPMENT § 801.7 Reference...

  16. Discussion on the method of environmental radiological impact assessment for the highway construction project

    International Nuclear Information System (INIS)

    Qiu Guohua

    2008-01-01

    Based on the characteristics and environmental radiological impact of the highway construction project, the basic procedure of environmental radiological impact assessment for the highway construction project is put forward, including analysis and determination of contamination sources, selection of evaluation factors, determination of assessment range and dose limit, environmental investigation, environmental impact prediction and assessment. The working method of each procedure is analyzed. (authors)

  17. Discussion and Outline of a Course on Methods of Teaching a Foreign Language.

    Science.gov (United States)

    Heiser, Mary

    This course, designed for instructing potential teaching assistants to teach college students a foreign language, concentrates on six major areas of preparation. A detailed outline covers: (1) course introduction and definitions, (2) applied linguistics, (3) approaches and methods, (4) testing, (5) classroom techniques, and (6) demonstrations.…

  18. Atomic spectrometry methods for wine analysis: A critical evaluation and discussion of recent applications

    Energy Technology Data Exchange (ETDEWEB)

    Grindlay, Guillermo, E-mail: guillermo.grindlay@ua.es [Department of Analytical Chemistry, Nutrition and Food Sciences, University of Alicante, PO Box 99, 03080 Alicante (Spain); Mora, Juan; Gras, Luis [Department of Analytical Chemistry, Nutrition and Food Sciences, University of Alicante, PO Box 99, 03080 Alicante (Spain); Loos-Vollebregt, Margaretha T.C. de [Delft University of Technology, Faculty of Applied Sciences, Analytical Biotechnology, Julianalaan 67, 2628 BC Delft (Netherlands)

    2011-04-08

    The analysis of wine is of great importance since wine components strongly determine its stability, organoleptic or nutrition characteristics. In addition, wine analysis is also important to prevent fraud and to assess toxicological issues. Among the different analytical techniques described in the literature, atomic spectrometry has been traditionally employed for elemental wine analysis due to its simplicity and good analytical figures of merit. The scope of this review is to summarize the main advantages and drawbacks of various atomic spectrometry techniques for elemental wine analysis. Special attention is paid to interferences (i.e. matrix effects) affecting the analysis as well as the strategies available to mitigate them. Finally, latest studies about wine speciation are briefly discussed.

  19. Atomic spectrometry methods for wine analysis: a critical evaluation and discussion of recent applications.

    Science.gov (United States)

    Grindlay, Guillermo; Mora, Juan; Gras, Luis; de Loos-Vollebregt, Margaretha T C

    2011-04-08

    The analysis of wine is of great importance since wine components strongly determine its stability, organoleptic or nutrition characteristics. In addition, wine analysis is also important to prevent fraud and to assess toxicological issues. Among the different analytical techniques described in the literature, atomic spectrometry has been traditionally employed for elemental wine analysis due to its simplicity and good analytical figures of merit. The scope of this review is to summarize the main advantages and drawbacks of various atomic spectrometry techniques for elemental wine analysis. Special attention is paid to interferences (i.e. matrix effects) affecting the analysis as well as the strategies available to mitigate them. Finally, latest studies about wine speciation are briefly discussed. Copyright © 2011 Elsevier B.V. All rights reserved.

  20. Discussion of plastic instabilities of a pressure vessel by means of the finite element method

    International Nuclear Information System (INIS)

    Laemmer, H.; Ritter, B.; Tsakmakis, C.

    1994-06-01

    In this report the influence of geometrical and thermal imperfections on the load-carrying capacity of pressure vessels has been studied by means of the ABAQUS finite element code. Using a thermo-plasticity model for finite strains failure due to plastic instability has been investigated. The parameters needed for this model were identified with uniaxial tensile tests. The parameters were fitted in such a way that necking of the tensile rod was described in a satisfactory manner. Starting from the tensile rod the influence of imperfections on necking of a structure is discussed. Axisymmetric and three dimensional calculations showed that for a sufficient size of the imperfection necking can be obtained. As expected, the maximum internal pressure at failure and the beginning of localization of plastic deformations depend on the size of the imperfection. (orig.) [de

  1. Atomic spectrometry methods for wine analysis: A critical evaluation and discussion of recent applications

    International Nuclear Information System (INIS)

    Grindlay, Guillermo; Mora, Juan; Gras, Luis; Loos-Vollebregt, Margaretha T.C. de

    2011-01-01

    The analysis of wine is of great importance since wine components strongly determine its stability, organoleptic or nutrition characteristics. In addition, wine analysis is also important to prevent fraud and to assess toxicological issues. Among the different analytical techniques described in the literature, atomic spectrometry has been traditionally employed for elemental wine analysis due to its simplicity and good analytical figures of merit. The scope of this review is to summarize the main advantages and drawbacks of various atomic spectrometry techniques for elemental wine analysis. Special attention is paid to interferences (i.e. matrix effects) affecting the analysis as well as the strategies available to mitigate them. Finally, latest studies about wine speciation are briefly discussed.

  2. Does discussing sexually transmissible infections or HIV with a parent increase condom use among young women using other contraceptive methods?

    Science.gov (United States)

    Bradley, Heather; Leichliter, Jami S; Gift, Thomas L

    2013-03-01

    Young people may be more likely to use condoms if they discuss sexual risks with their parents. However, no previous study has examined whether discussing sexual risks with a parent is differently associated with condom use among women using and not using other contraceptive methods. Using weighted data from the 2006-2008 National Survey of Family Growth, we examined condom use at last sex among 1206 sexually active unmarried women aged 15-24 years. Using logistic regression, we examined the association between condom use and discussing sexually transmissible infections (STIs) with parents before the age of 18 years, adjusted for women's characteristics (age, ethnicity, income and condom use at first sex). We estimated the predicted probability of condom use by whether women discussed STIs with parents, stratified by use of other contraceptive methods. Overall, 53% of women used condoms at last sex. Among 564 women using other contraceptives, 42% used condoms, versus 64% of 642 women not using other contraceptive methods (P<0.01). After adjustment for covariates, the predicted probability of condom use among women using other contraceptives was 47% among women who discussed STIs with their parents (v. 31% of those not discussing STIs; P<0.01). Among women not using other contraceptives, the predicted probability of condom use remained 64% regardless of whether they discussed STIs with their parents. Young women who use other contraceptive methods are less likely to use condoms, but discussing STIs with parents is associated with increased condom use among these women.

  3. Development of a RIA for clonidine and its comparison with the reference methods

    International Nuclear Information System (INIS)

    Arndts, D.; Staehle, H.; Foerster, H.J.

    1981-01-01

    A radioimmunoassay for clonidine was optimized by introducing, as a tracer ligand, an iodinized clonidine derivative specifically labeled with more than 500 Ci/mMol. The detection limit of clonidine was 10 pg/ml. The high assay specificity was demonstrated by a double isotope technique. The intraassay coefficient of variance (VK) was less than 4% for any concentration, the interassay VK did not exceed 8.3%. The assay reliability was increased when the plasma samples were diluted 1:5, prior to analysis, in normal human blood plasma, which was also used for the preparation of the calibration samples. In a comparative manner, this assay system was subjected to double-blind accuracy control tests, including all other reference methods so far described for clonidine analysis in blood plasma samples. The RIA technique presented here turned out to be the most sensitive and most reliable method, requiring, moreover, the smallest volumes of blood plasma (0.05 ml). This procedure was appropriate for routine tests, since one technician could perform 500 sample analyses a day. The advantages and disadvantages of each method are discussed

  4. Discussion on Regression Methods Based on Ensemble Learning and Applicability Domains of Linear Submodels.

    Science.gov (United States)

    Kaneko, Hiromasa

    2018-02-26

    To develop a new ensemble learning method and construct highly predictive regression models in chemoinformatics and chemometrics, applicability domains (ADs) are introduced into the ensemble learning process of prediction. When estimating values of an objective variable using subregression models, only the submodels with ADs that cover a query sample, i.e., the sample is inside the model's AD, are used. By constructing submodels and changing a list of selected explanatory variables, the union of the submodels' ADs, which defines the overall AD, becomes large, and the prediction performance is enhanced for diverse compounds. By analyzing a quantitative structure-activity relationship data set and a quantitative structure-property relationship data set, it is confirmed that the ADs can be enlarged and the estimation performance of regression models is improved compared with traditional methods.

  5. Extending the use of references to the literature: Lessons from a content analysis of mixed method case exemplars

    DEFF Research Database (Denmark)

    Creamer, Elizabeth G.; Musaeus, Peter; Edwards, Cherie

    2018-01-01

    The role of references to the literature in a scholarly publication is conceived principally in terms of its foundational role in establishing the need for a study and framing its contribution. This methodological inquiry used content analysis to examine how authors of mixed methods exemplars dep...... of relevant literature may be particularly important in mixed methods research where a strong emergent strand often introduces heightens awareness that a phenomenon is more complex than initially conceived.......The role of references to the literature in a scholarly publication is conceived principally in terms of its foundational role in establishing the need for a study and framing its contribution. This methodological inquiry used content analysis to examine how authors of mixed methods exemplars...... deployed references to the literature in the discussion section of their manuscripts. These authors also deployed references to literature in the discussion section to support statements about the implications and significance of the research or to explain unexpected findings. Immersion in a broad range...

  6. Discussion on the installation checking method of precast composite floor slab with lattice girders

    Science.gov (United States)

    Chen, Li; Jin, Xing; Wang, Yahui; Zhou, Hele; Gu, Jianing

    2018-03-01

    Based on the installation checking requirements of China’s current standards and the international norms for prefabricated structural precast components, it proposed an installation checking method for precast composite floor slab with lattice girders. By taking an equivalent composite beam consisted of a single lattice girder and the precast concrete slab as the checking object, compression instability stress of upper chords and yield stress of slab distribution reinforcement at the maximum positive moment, tensile yield stress of upper chords, slab normal section normal compression stress and shear instability stress of diagonal bars at the maximum negative moment were checked. And the bending stress and deflection of support beams, strength and compression stability bearing capacity of the vertical support, shear bearing capacity of the bolt and compression bearing capacity of steel tube wall at the bolt were checked at the same time. Every different checking object was given a specific load value and load combination. Application of installation checking method was given and testified by example.

  7. [Data validation methods and discussion on Chinese materia medica resource survey].

    Science.gov (United States)

    Zhang, Yue; Ma, Wei-Feng; Zhang, Xiao-Bo; Zhu, Shou-Dong; Guo, Lan-Ping; Wang, Xing-Xing

    2013-07-01

    From the beginning of the fourth national survey of the Chinese materia medica resources, there were 22 provinces have conducted pilots. The survey teams have reported immense data, it put forward the very high request to the database system construction. In order to ensure the quality, it is necessary to check and validate the data in database system. Data validation is important methods to ensure the validity, integrity and accuracy of census data. This paper comprehensively introduce the data validation system of the fourth national survey of the Chinese materia medica resources database system, and further improve the design idea and programs of data validation. The purpose of this study is to promote the survey work smoothly.

  8. A method to calibrate a solar pyranometer for measuring reference diffuse irradiance

    Energy Technology Data Exchange (ETDEWEB)

    Reda, I.; Stoffel, T.; Myers, D. [National Renewable Energy Laboratory, Golden, CO (United States)

    2003-02-01

    Accurate pyranometer calibrations, traceable to internationally recognized standards, are critical for solar irradiance measurements. One calibration method is the component summation, where the pyranometers are calibrated outdoors under clear sky conditions, and the reference global solar irradiance is calculated as the sum of two reference components, the diffuse and subtended beam solar irradiances. The beam component is measured with pyrheliometers traceable to the World Radiometric Reference, while there is no internationally recognized reference for the diffuse component. In the absence of such a reference, we present a method to consistently calibrate pyranometers for measuring the diffuse component with an estimated uncertainty of {+-} (3% of reading +1 W/m{sup 2}). The method is based on using a modified shade/unshade method, and pyranometers with less than 1 W/m{sup 2} thermal offset errors. We evaluated the consistency of our method by calibrating three pyranometers four times. Calibration results show that the responsivity change is within {+-} 0.52% for the three pyranometers. We also evaluated the effect of calibrating pyranometers unshaded, then using them shaded to measure diffuse irradiance. We calibrated three unshaded pyranometers using the component summation method. Their outdoor measurements of clear sky diffuse irradiance, from sunrise to sundown, showed that the three calibrated pyranometers can be used to measure the diffuse irradiance to within {+-} 1.4 W/m{sup 2} variation from the reference irradiance. (author)

  9. 75 FR 22126 - Office of Research and Development; Ambient Air Monitoring Reference and Equivalent Methods...

    Science.gov (United States)

    2010-04-27

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9142-1] Office of Research and Development; Ambient Air Monitoring Reference and Equivalent Methods: Designation of One New Equivalent Method AGENCY: Environmental Protection Agency. ACTION: Notice of the designation of one new equivalent method for monitoring ambient air...

  10. 75 FR 9894 - Office of Research and Development; Ambient Air Monitoring Reference and Equivalent Methods...

    Science.gov (United States)

    2010-03-04

    ..., Research Triangle Park, North Carolina 27711. Designation of this new equivalent method is intended to... ENVIRONMENTAL PROTECTION AGENCY [FRL-9121-6] Office of Research and Development; Ambient Air Monitoring Reference and Equivalent Methods: Designation of One New Equivalent Method AGENCY: Environmental...

  11. 76 FR 15974 - Office of Research and Development; Ambient Air Monitoring Reference and Equivalent Methods...

    Science.gov (United States)

    2011-03-22

    ..., Research Triangle Park, North Carolina 27711. Designation of these new equivalent methods is intended to... ENVIRONMENTAL PROTECTION AGENCY [FRL-9285-2] Office of Research and Development; Ambient Air Monitoring Reference and Equivalent Methods: Designation of Four New Equivalent Methods AGENCY: Environmental...

  12. 76 FR 62402 - Office of Research and Development; Ambient Air Monitoring Reference and Equivalent Methods...

    Science.gov (United States)

    2011-10-07

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9476-7] Office of Research and Development; Ambient Air Monitoring Reference and Equivalent Methods; Designation of One New Equivalent Method AGENCY: Environmental Protection Agency. ACTION: Notice of the designation of one new equivalent method for monitoring ambient air...

  13. 75 FR 51039 - Office of Research and Development; Ambient Air Monitoring Reference and Equivalent Methods...

    Science.gov (United States)

    2010-08-18

    ..., Research Triangle Park, North Carolina 27711. Designation of these new equivalent methods is intended to... ENVIRONMENTAL PROTECTION AGENCY [FRL-9190-5] Office of Research and Development; Ambient Air Monitoring Reference and Equivalent Methods: Designation of Two New Equivalent Methods AGENCY: Environmental...

  14. 75 FR 30022 - Office of Research and Development; Ambient Air Monitoring Reference and Equivalent Methods...

    Science.gov (United States)

    2010-05-28

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9156-1] Office of Research and Development; Ambient Air Monitoring Reference and Equivalent Methods: Designation of One New Equivalent Method AGENCY: Environmental Protection Agency. ACTION: Notice of the designation of one new equivalent method for monitoring ambient air...

  15. De novo clustering methods outperform reference-based methods for assigning 16S rRNA gene sequences to operational taxonomic units

    Directory of Open Access Journals (Sweden)

    Sarah L. Westcott

    2015-12-01

    VSEARCH have a high level of sensitivity to detect reference sequences, the specificity of those matches was poor relative to the true best match.Discussion. Our analysis calls into question the quality and stability of OTU assignments generated by the open and closed-reference methods as implemented in current version of QIIME. This study demonstrates that de novo methods are the optimal method of assigning sequences into OTUs and that the quality of these assignments needs to be assessed for multiple methods to identify the optimal clustering method for a particular dataset.

  16. A simple method for HPLC retention time prediction: linear calibration using two reference substances.

    Science.gov (United States)

    Sun, Lei; Jin, Hong-Yu; Tian, Run-Tao; Wang, Ming-Juan; Liu, Li-Na; Ye, Liu-Ping; Zuo, Tian-Tian; Ma, Shuang-Cheng

    2017-01-01

    Analysis of related substances in pharmaceutical chemicals and multi-components in traditional Chinese medicines needs bulk of reference substances to identify the chromatographic peaks accurately. But the reference substances are costly. Thus, the relative retention (RR) method has been widely adopted in pharmacopoeias and literatures for characterizing HPLC behaviors of those reference substances unavailable. The problem is it is difficult to reproduce the RR on different columns due to the error between measured retention time (t R ) and predicted t R in some cases. Therefore, it is useful to develop an alternative and simple method for prediction of t R accurately. In the present study, based on the thermodynamic theory of HPLC, a method named linear calibration using two reference substances (LCTRS) was proposed. The method includes three steps, procedure of two points prediction, procedure of validation by multiple points regression and sequential matching. The t R of compounds on a HPLC column can be calculated by standard retention time and linear relationship. The method was validated in two medicines on 30 columns. It was demonstrated that, LCTRS method is simple, but more accurate and more robust on different HPLC columns than RR method. Hence quality standards using LCTRS method are easy to reproduce in different laboratories with lower cost of reference substances.

  17. Qualitative, quantitative, and data mining methods for analyzing log data to characterize students' learning strategies and behaviors [discussant

    NARCIS (Netherlands)

    Baker, Ryan S.J.d.; Gobert, Janice D.; van Joolingen, Wouter

    2010-01-01

    This symposium addresses how different classes of research methods, all based upon the use of log data from educational software, can facilitate the analysis of students’ learning strategies and behaviors. To this end, four multi-method programs of research are discussed, including the use of

  18. Investigation of sol-gel transition by rheological methods. Part II. Results and discussion.

    Directory of Open Access Journals (Sweden)

    KUDRYAVTSEV Pavel Gennadievich

    2017-10-01

    Full Text Available In this work rheological studies of the gelling process were carried out. We have developed a measuring system for studying the rheology of the gelation process. It consisted of several measuring cells of the Weiler-Rebinder type, system for automatic regulation of the composition of the medium and thermostabilization system. This complex is designed to measure the dependence of the value of the ultimate shear stress as a function of time, from the start of the sol-gel transition to the complete conversion of the sol to the gel. The developed device has a wide range of measured values of critical shear stresses τ0 = (0,05÷50000 Dyne/cm2. Using the developed instrument, it was possible to establish the shape of the initial section of the curve τ0 = f(t and develop a methodology for more accurate determination of gelation time. The developed method proved that the classical method for determining the start time of the sol-gel transition using the point of intersection of the tangent to the linear part of the rheological curve τ0 = f(t, gives significantly distorted results. A new phenomenon has been discovered: the kinetic curves in the coordinates of the Avrami-Erofeev-Bogolyubov equation have an inflection point which separates the kinetic curve into two parts, the initial and the final. It was found that the constant k in the Avrami–Erofeev–Bogolyubov equation does not depend on the temperature and is the same for both the initial and final parts of the kinetic curve. It depends only on the chemical nature of the reacting system. It was found that for the initial section of the kinetic curves, the value of the parameter n in the Avrami-Erofeev-Bogolyubov equation was n = 23,4±2,8 and, unlike the final section of the rheological curve, does not depend on temperature. A large value of this parameter can be interpreted as the average number of directions of growth of a fractal aggregate during its growth. The value of this parameter

  19. Effect of reference loads on fracture mechanics analysis of surface cracked pipe based on reference stress method

    International Nuclear Information System (INIS)

    Shim, Do Jun; Son, Beom Goo; Kim, Young Jin; Kim, Yun Jae

    2004-01-01

    To investigate relevance of the definition of the reference stress to estimate J and C * for surface crack problems, this paper compares FE J and C * results for surface cracked pipes with those estimated according to the reference stress approach using various definitions of the reference stress. Pipes with part circumferential inner surface crack and finite internal axial crack are considered, subject to internal pressure and global bending. The crack depth and aspect ratio are systematically varied. The reference stress is defined in four different ways using (I) the local limit load, (II) the global limit load, (III) the global limit load determined from the FE limit analysis, and (IV) the optimised reference load. It is found that the reference stress based on the local limit load gives overall excessively conservative estimates of J and C * . Use of the global limit load clearly reduces the conservatism, compared to that of the local limit load, although it can provide sometimes non-conservative estimates of J and C * . The use of the FE global limit load gives overall non-conservative estimates of J and C * . The reference stress based on the optimised reference load gives overall accurate estimates of J and C * , compared to other definitions of the reference stress. Based on the present finding, general guidance on the choice of the reference stress for surface crack problems is given

  20. Standard Test Methods for Electrical Performance of Nonconcentrator Terrestrial Photovoltaic Modules and Arrays Using Reference Cells

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2008-01-01

    1.1 These test methods cover the electrical performance of photovoltaic modules and arrays under natural or simulated sunlight using a calibrated reference cell. 1.1.1 These test methods allow a reference module to be used instead of a reference cell provided the reference module has been calibrated using these test methods against a calibrated reference cell. 1.2 Measurements under a variety of conditions are allowed; results are reported under a select set of reporting conditions (RC) to facilitate comparison of results. 1.3 These test methods apply only to nonconcentrator terrestrial modules and arrays. 1.4 The performance parameters determined by these test methods apply only at the time of the test, and imply no past or future performance level. 1.5 These test methods apply to photovoltaic modules and arrays that do not contain series-connected photovoltaic multijunction devices; such module and arrays should be tested according to Test Methods E 2236. 1.6 The values stated in SI units are to be re...

  1. A self-reference PRF-shift MR thermometry method utilizing the phase gradient

    International Nuclear Information System (INIS)

    Langley, Jason; Potter, William; Phipps, Corey; Zhao Qun; Huang Feng

    2011-01-01

    In magnetic resonance (MR) imaging, the most widely used and accurate method for measuring temperature is based on the shift in proton resonance frequency (PRF). However, inter-scan motion and bulk magnetic field shifts can lead to inaccurate temperature measurements in the PRF-shift MR thermometry method. The self-reference PRF-shift MR thermometry method was introduced to overcome such problems by deriving a reference image from the heated or treated image, and approximates the reference phase map with low-order polynomial functions. In this note, a new approach is presented to calculate the baseline phase map in self-reference PRF-shift MR thermometry. The proposed method utilizes the phase gradient to remove the phase unwrapping step inherent to other self-reference PRF-shift MR thermometry methods. The performance of the proposed method was evaluated using numerical simulations with temperature distributions following a two-dimensional Gaussian function as well as phantom and in vivo experimental data sets. The results from both the numerical simulations and experimental data show that the proposed method is a promising technique for measuring temperature. (note)

  2. Isotachophoresis as a candidate reference method in analytical chemistry. Determination of sodium in serum

    NARCIS (Netherlands)

    Lemmens, A.A.G.; Reijenga, J.C.; Everaerts, F.M.; Janssen, R.T.P.; Hulsman, J.A.R.J.; Meijers, C.A.M.

    1985-01-01

    Isotachophoresis seems a likely candidate for a reference method, as it is more accurate and precise than common routine methods. The response is highly linear and depends on a well defined transport number of the leading ion, stability of the driving current, mobility of the separand, which is well

  3. An independent accurate reference method for the determination of chromium in biological materials

    NARCIS (Netherlands)

    Lagerwaard, A.; Woittiez, J.R.W.; de Goeij, J.J.M.

    1994-01-01

    A method for the determination of Cr in biological materials with high accuracy is reported for use as an independent reference method. It is based on radiochemical neutron activation analysis (RNAA) in combination with an individual yield determination based on the online yield principle. A

  4. Reference methods and materials. A programme of support for regional and global marine pollution assessments

    International Nuclear Information System (INIS)

    1990-01-01

    This document describes a programme of comprehensive support for regional and global marine pollution assessments developed by the United Nations Environment Programme (UNEP) in cooperation with the International Atomic Energy Agency (IAEA) and the Intergovernmental Oceanographic Commission (IOC) and with the collaboration of a number of other United Nations Specialized agencies including the Food and Agriculture Organisation (FAO), the World Meteorological Organisation (WMO), the World Health Organisation (WHO) and the International Maritime Organisation (IMO). Two of the principle components of this programme, Reference Methods and Reference materials are given special attention in this document and a full Reference Method catalogue is included, giving details of over 80 methods currently available or in an advanced stage of preparation and testing. It is important that these methods are seen as a functional component of a much wider strategy necessary for assuring good quality and intercomparable data for regional and global pollution monitoring and the user is encouraged to read this document carefully before employing Reference Methods and Reference Materials in his/her laboratory. 3 figs

  5. Investigation of the effects of group discussion on the empowerment of patients with hypertension who were referred to two health centers in Tehran in 1390

    Directory of Open Access Journals (Sweden)

    Nasrin Kheibar

    2014-04-01

    Results: The average age of the subjects was 54 ± 8.4 years and 34.4% of the participants had a history of hypertension for 5 years. Group discussions could lead to improve the average empowerment of individuals (P=0.04. Furthermore, among all the aspects of empowerment, group discussions had the greatest impact on the perception and sensitivity levels (P=0.001 and P=0.02 respectively. Conclusion: In patients with hypertension, group discussions can lead to increased perception and sensitivity levels and also enhance the ability of individuals to control their lifestyles.

  6. 77 FR 55832 - Ambient Air Monitoring Reference and Equivalent Methods: Designation of a New Equivalent Method

    Science.gov (United States)

    2012-09-11

    ... automated monitoring method utilizing a measurement principle based on sample collection by filtration and... 58. Questions concerning the commercial availability or technical aspects of the method should be...

  7. Project-Based Learning Using Discussion and Lesson-Learned Methods via Social Media Model for Enhancing Problem Solving Skills

    Science.gov (United States)

    Jewpanich, Chaiwat; Piriyasurawong, Pallop

    2015-01-01

    This research aims to 1) develop the project-based learning using discussion and lesson-learned methods via social media model (PBL-DLL SoMe Model) used for enhancing problem solving skills of undergraduate in education student, and 2) evaluate the PBL-DLL SoMe Model used for enhancing problem solving skills of undergraduate in education student.…

  8. 77 FR 32632 - Ambient Air Monitoring Reference and Equivalent Methods: Designation of Three New Equivalent Methods

    Science.gov (United States)

    2012-06-01

    ... Methods: Designation of Three New Equivalent Methods AGENCY: Environmental Protection Agency. ACTION... accordance with 40 CFR Part 53, three new equivalent methods: One for measuring concentrations of nitrogen... INFORMATION: In accordance with regulations at 40 CFR Part 53, the EPA evaluates various methods for...

  9. 78 FR 67360 - Ambient Air Monitoring Reference and Equivalent Methods: Designation of Five New Equivalent Methods

    Science.gov (United States)

    2013-11-12

    ... Methods: Designation of Five New Equivalent Methods AGENCY: Office of Research and Development; Environmental Protection Agency (EPA). ACTION: Notice of the designation of five new equivalent methods for...) has designated, in accordance with 40 CFR Part 53, five new equivalent methods, one for measuring...

  10. 77 FR 60985 - Ambient Air Monitoring Reference and Equivalent Methods: Designation of Three New Equivalent Methods

    Science.gov (United States)

    2012-10-05

    ... Methods: Designation of Three New Equivalent Methods AGENCY: Environmental Protection Agency. ACTION: Notice of the designation of three new equivalent methods for monitoring ambient air quality. SUMMARY... equivalent methods, one for measuring concentrations of PM 2.5 , one for measuring concentrations of PM 10...

  11. Normalization Methods and Selection Strategies for Reference Materials in Stable Isotope Analyses - Review

    International Nuclear Information System (INIS)

    Skrzypek, G.; Sadler, R.; Paul, D.; Forizs, I.

    2011-01-01

    A stable isotope analyst has to make a number of important decisions regarding how to best determine the 'true' stable isotope composition of analysed samples in reference to an international scale. It has to be decided which reference materials should be used, the number of reference materials and how many repetitions of each standard is most appropriate for a desired level of precision, and what normalization procedure should be selected. In this paper we summarise what is known about propagation of uncertainties associated with normalization procedures and propagation of uncertainties associated with reference materials used as anchors for the determination of 'true' values for δ''1''3C and δ''1''8O. Normalization methods Several normalization methods transforming the 'raw' value obtained from mass spectrometers to one of the internationally recognized scales has been developed. However, as summarised by Paul et al. different normalization transforms alone may lead to inconsistencies between laboratories. The most common normalization procedures are: single-point anchoring (versus working gas and certified reference standard), modified single-point normalization, linear shift between the measured and the true isotopic composition of two certified reference standards, two-point and multipoint linear normalization methods. The accuracy of these various normalization methods has been compared by using analytical laboratory data by Paul et al., with the single-point and normalization versus tank calibrations resulting in the largest normalization errors, and that also exceed the analytical uncertainty recommended for δ 13 C. The normalization error depends greatly on the relative differences between the stable isotope composition of the reference material and the sample. On the other hand, the normalization methods using two or more certified reference standards produces a smaller normalization error, if the reference materials are bracketing the whole range of

  12. Model Reference Adaptive Control of the Air Flow Rate of Centrifugal Compressor Using State Space Method

    International Nuclear Information System (INIS)

    Han, Jaeyoung; Jung, Mooncheong; Yu, Sangseok; Yi, Sun

    2016-01-01

    In this study, a model reference adaptive controller is developed to regulate the outlet air flow rate of centrifugal compressor for automotive supercharger. The centrifugal compressor is developed using the analytical based method to predict the transient behavior of operating and the designed model is validated with experimental data to confirm the system accuracy. The model reference adaptive control structure consists of a compressor model and a MRAC(model reference adaptive control) mechanism. The feedback control do not robust with variation of system parameter but the applied adaptive control is robust even if the system parameter is changed. As a result, the MRAC was regulated to reference air flow rate. Also MRAC was found to be more robust control compared with the feedback control even if the system parameter is changed.

  13. Model Reference Adaptive Control of the Air Flow Rate of Centrifugal Compressor Using State Space Method

    Energy Technology Data Exchange (ETDEWEB)

    Han, Jaeyoung; Jung, Mooncheong; Yu, Sangseok [Chungnam Nat’l Univ., Daejeon (Korea, Republic of); Yi, Sun [North Carolina A and T State Univ., Raleigh (United States)

    2016-08-15

    In this study, a model reference adaptive controller is developed to regulate the outlet air flow rate of centrifugal compressor for automotive supercharger. The centrifugal compressor is developed using the analytical based method to predict the transient behavior of operating and the designed model is validated with experimental data to confirm the system accuracy. The model reference adaptive control structure consists of a compressor model and a MRAC(model reference adaptive control) mechanism. The feedback control do not robust with variation of system parameter but the applied adaptive control is robust even if the system parameter is changed. As a result, the MRAC was regulated to reference air flow rate. Also MRAC was found to be more robust control compared with the feedback control even if the system parameter is changed.

  14. Assessment of the reference stress method for combined tensile bending and thermal loading

    International Nuclear Information System (INIS)

    Philipp, A.; Munz, D.

    1984-01-01

    The reference stress method has been investigated for combined tensile, bending and thermal loading by considering a uniformly bent beam subjected to superimposed tensile stress and lateral temperature gradients. The creep deformation of the beam can be calculated numerically applying a Norton-type creep law. It turns out that the ratio of curvature rate to strain at the outer fiber depends on the creep exponent. Therefore, the reference stresses for these two quantities must be expected to be different in general. In most load cases, however, it is possible to determine a reference stress which can be used to describe the complete deformation of the beam. The only exception is the case of high tensile loading if the side exposed to higher tensile stress is cooler. Approximate solutions for the reference stress which rely on elastic and limit analyses, can be used only for estimates because they lead to extremely non-conservative predictions. (author)

  15. [Discussion on Quality Evaluation Method of Medical Device During Life-Cycle in Operation Based on the Analytic Hierarchy Process].

    Science.gov (United States)

    Zheng, Caixian; Zheng, Kun; Shen, Yunming; Wu, Yunyun

    2016-01-01

    The content related to the quality during life-cycle in operation of medical device includes daily use, repair volume, preventive maintenance, quality control and adverse event monitoring. In view of this, the article aims at discussion on the quality evaluation method of medical devices during their life cycle in operation based on the Analytic Hierarchy Process (AHP). The presented method is proved to be effective by evaluating patient monitors as example. The method presented in can promote and guide the device quality control work, and it can provide valuable inputs to decisions about purchase of new device.

  16. Effects of an additional small group discussion to cognitive achievement and retention in basic principles of bioethics teaching methods

    Directory of Open Access Journals (Sweden)

    Dedi Afandi

    2009-03-01

    Full Text Available Aim The place of ethics in undergraduate medical curricula is essential but the methods of teaching medical ethics did not show substantial changes. “Basic principles of bioethics” is the best knowledge to develop student’s reasoning analysis in medical ethics In this study, we investigate the effects of an additional small group discussion in basic principles of bioethics conventional lecture methods to cognitive achievement and retention. This study was a randomized controlled trial with parallel design. Cognitive scores of the basic principles of bioethics as a parameter was measured using basic principles of bioethics (Kaidah Dasar Bioetika, KDB test. Both groups were attending conventional lectures, then the intervention group got an additional small group discussion.Result Conventional lectures with or without small group discussion significantly increased cognitive achievement of basic principles of bioethics (P= 0.001 and P= 0.000, respectively, and there were significant differences in cognitive achievement and retention between the 2 groups (P= 0.000 and P= 0.000, respectively.Conclusion Additional small group discussion method improved cognitive achievement and retention of basic principles of bioethics. (Med J Indones 2009; 18: 48-52Keywords: lecture, specification checklist, multiple choice questions

  17. A new method of 3-D cephalometry Part I: the anatomic Cartesian 3-D reference system.

    NARCIS (Netherlands)

    Swennen, G.R.J.; Schutyser, F.A.C.; Barth, E.L.; Groeve, P. De; Mey, A. De

    2006-01-01

    The purpose of this study was to present a new innovative three-dimensional (3-D) cephalometric method. Part I deals with the set-up and validation of a voxel-based semi-automatic 3-D cephalometric reference system. The CT data (DICOM 3.0 files) of 20 control patients with normal skeletal

  18. Determination of trace elements in standard reference materials by the ko-standardization method

    International Nuclear Information System (INIS)

    Smodis, B.; Jacimovic, R.; Stegnar, P.; Jovanovic, S.

    1990-01-01

    The k o -standardization method is suitable for routine multielement determinations by reactor neutron activation analysis (NAA). Investigation of NIST standard reference materials SRM 1571 Orchard Leaves, SRM 1572 Citrus leaves, and SRM 1573 Tomato Leaves showed the systematic error of 12 certified elements determined to be less than 8%. Thirty-four elements were determined in NIST proposed SRM 1515 Apple Leaves

  19. Determination of element concentrations in biological reference materials by solid sampling and other analytical methods

    International Nuclear Information System (INIS)

    Schauenburg, H.; Weigert, P.

    1992-01-01

    Using solid sampling with graphite furnace atomic absorption spectrometry (GFAAS), values for cadmium, copper, lead and zinc in six biological reference materials were obtained from up to four laboratories participating in three collaborative studies. These results are compared with those obtained with other methods used in routine analysis from laboratories of official food control. Under certain conditions solid sampling with GFAAS seems to be suitable for routine analysis as well as conventional methods. (orig.)

  20. Neutron activation analysis of reference materials by the k sub 0 standardization and relative methods

    Energy Technology Data Exchange (ETDEWEB)

    Freitas, M C; Martinho, E [LNETI/ICEN, Sacavem (Portugal)

    1989-04-15

    Instrumental neutron activation analysis with the k{sub o}-standardization method was applied to eight geological, environmental and biological reference materials, including leaves, blood, fish, sediments, soils and limestone. To a first approximation, the results were normally distributed around the certified values with a standard deviation of 10%. Results obtained by using the relative method based on well characterized multi-element standards for IAEA CRM Soil-7 are reported.

  1. A Practical MethodDiscussion using Matrix Diagram’ , ConnectingHuman Base-Liberal-and Engineering Base-Professional-

    Science.gov (United States)

    Shimada, Wataru

    In order to bring up talented people, it is a most important subject how to awake ‘Emotional Human Power’ , which is the origin of Autonomy and Creativity. A Practical MethodDiscussion using Matrix Diagram’ developed for improving ‘Emotional Human Power’ including ‘Communication Skill’ , is confirmed to be useful for connecting Human Base-Liberal-and Engineering Base-Professional-.

  2. Standard Test Method for Calibration of Primary Non-Concentrator Terrestrial Photovoltaic Reference Cells Using a Tabular Spectrum

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2010-01-01

    1.1 This test method is intended to be used for calibration and characterization of primary terrestrial photovoltaic reference cells to a desired reference spectral irradiance distribution, such as Tables G173. The recommended physical requirements for these reference cells are described in Specification E1040. Reference cells are principally used in the determination of the electrical performance of photovoltaic devices. 1.2 Primary photovoltaic reference cells are calibrated in natural sunlight using the relative spectral response of the cell, the relative spectral distribution of the sunlight, and a tabulated reference spectral irradiance distribution. 1.3 This test method requires the use of a pyrheliometer that is calibrated according to Test Method E816, which requires the use of a pyrheliometer that is traceable to the World Radiometric Reference (WRR). Therefore, reference cells calibrated according to this test method are traceable to the WRR. 1.4 This test method is a technique that may be used ...

  3. Recent advances in ratio primary reference measurement procedures (definitive methods) and their use in certification of reference materials and controlling assigned values in proficiency testing

    International Nuclear Information System (INIS)

    Dybczynski, R.S.; Polkowska-Motrenko, H.; Chajduk, E.; Danko, B.; Pyszynska, M.

    2014-01-01

    Three very accurate (definitive) methods by RNAA for the determination of Se, As and Fe respectively, which were recently elaborated in our laboratory, are reviewed and their use in certification of reference materials and in checking the assigned values in proficiency tests is demonstrated on several examples. According to VIM 3 nomenclature these methods may be called: ratio primary reference measurement procedures (RPRMPs). RPRMPs with their expanded uncertainties of 2.7-3.6 % are comparable to ID-MS methods and are the only methods of such high metrological quality which can be used for the determination of trace amounts of monoisotopic elements. (author)

  4. A novel no-reference objective stereoscopic video quality assessment method based on visual saliency analysis

    Science.gov (United States)

    Yang, Xinyan; Zhao, Wei; Ye, Long; Zhang, Qin

    2017-07-01

    This paper proposes a no-reference objective stereoscopic video quality assessment method with the motivation that making the effect of objective experiments close to that of subjective way. We believe that the image regions with different visual salient degree should not have the same weights when designing an assessment metric. Therefore, we firstly use GBVS algorithm to each frame pairs and separate both the left and right viewing images into the regions with strong, general and week saliency. Besides, local feature information like blockiness, zero-crossing and depth are extracted and combined with a mathematical model to calculate a quality assessment score. Regions with different salient degree are assigned with different weights in the mathematical model. Experiment results demonstrate the superiority of our method compared with the existed state-of-the-art no-reference objective Stereoscopic video quality assessment methods.

  5. A frequency domain global parameter estimation method for multiple reference frequency response measurements

    Science.gov (United States)

    Shih, C. Y.; Tsuei, Y. G.; Allemang, R. J.; Brown, D. L.

    1988-10-01

    A method of using the matrix Auto-Regressive Moving Average (ARMA) model in the Laplace domain for multiple-reference global parameter identification is presented. This method is particularly applicable to the area of modal analysis where high modal density exists. The method is also applicable when multiple reference frequency response functions are used to characterise linear systems. In order to facilitate the mathematical solution, the Forsythe orthogonal polynomial is used to reduce the ill-conditioning of the formulated equations and to decouple the normal matrix into two reduced matrix blocks. A Complex Mode Indicator Function (CMIF) is introduced, which can be used to determine the proper order of the rational polynomials.

  6. [Results of a structurized discussion within the framework of abortion with particular reference to problems of pregnancy, conflict and related topics (author's transl)].

    Science.gov (United States)

    Woynar, W; Schuster, E; Oberheuser, F

    1980-02-01

    Structured discussions within the framework of social counseling were held with 112 patients in connection with abortion. They were structured according to sociopsychologoical criteria in order to discover any hidden conflicts prevailing in those patients seeking abortion. It became clear that there was a discrepancy between the individual expectation and its translation into reality. Also there was a situation in which too much was demanded of the patient, resulting in an inability to cope with the factors governing her life with subsequent fear of mental and social isolation. Sociologically speaking, the group was divided between elderly socially secured patients who already had children and young patients still undergoing educational or vocational training. (Authors' modified)

  7. A Reference Point Construction Method Using Mobile Terminals and the Indoor Localization Evaluation in the Centroid Method

    Directory of Open Access Journals (Sweden)

    Takahiro Yamaguchi

    2015-05-01

    Full Text Available As smartphones become widespread, a variety of smartphone applications are being developed. This paper proposes a method for indoor localization (i.e., positioning that uses only smartphones, which are general-purpose mobile terminals, as reference point devices. This method has the following features: (a the localization system is built with smartphones whose movements are confined to respective limited areas. No fixed reference point devices are used; (b the method does not depend on the wireless performance of smartphones and does not require information about the propagation characteristics of the radio waves sent from reference point devices, and (c the method determines the location at the application layer, at which location information can be easily incorporated into high-level services. We have evaluated the level of localization accuracy of the proposed method by building a software emulator that modeled an underground shopping mall. We have confirmed that the determined location is within a small area in which the user can find target objects visually.

  8. Influence of lubricant on the pitting capacity of gears. Comparison and discussion of main pitting test methods

    Energy Technology Data Exchange (ETDEWEB)

    Hoehn, Bernd-Robert; Oster, Peter; Tobie, Thomas; Hergesell, Maria [Forschungsstelle fuer Zahnraeder und Getriebebau, Technische Univ. Muenchen, Garching (Germany)

    2009-07-01

    The lubricant in a gearbox should provide a separating lubricating film between the meshing teeth. Furthermore its main task is the evacuation of the developing heat. Hence the lubricant is also an important influence parameter on the pitting life time of gearsets. Due to the constantly rising demands for higher power transmission of gearsets, also higher demands are made against the performance of the lubricants. In order to quantify the capability and to choose the appropriate lubricant for each application, reliable testing methods are necessary. Therefor today different testing methods are available. Two of the main pitting testing methods are the Standard Pittingtest according to FVA 2/IV [2] and its advancement, the Practice Relevant Pittingtest according to FVA 371 [4]. For the Practice Relevant Pittingtest test gears with profile modification and lengthwise crowning are used, which are superfinished. For the introduction of the Practice Relevant Pittingtest into industrial application a round robin test was performed in co-operation with FVA and DGMK. This paper is discussing the today usual testing methods regarding the pitting load capacity of lubricants and their characteristics in comparison. Furthermore the results of the round robin test and further example results, including pictures of typical pittings, are presented. In addition it is demonstrated, how to deal with the results. On the basis of test experience, knowledge from research projects and other examples typical questions concerning the different testing methods are discussed. Thereby essential requirements for reliable and reproducible results are pointed out and possible limits for the application of the test methods are represented. (orig.)

  9. The establishment of tocopherol reference intervals for Hungarian adult population using a validated HPLC method.

    Science.gov (United States)

    Veres, Gábor; Szpisjak, László; Bajtai, Attila; Siska, Andrea; Klivényi, Péter; Ilisz, István; Földesi, Imre; Vécsei, László; Zádori, Dénes

    2017-09-01

    Evidence suggests that decreased α-tocopherol (the most biologically active substance in the vitamin E group) level can cause neurological symptoms, most likely ataxia. The aim of the current study was to first provide reference intervals for serum tocopherols in the adult Hungarian population with appropriate sample size, recruiting healthy control subjects and neurological patients suffering from conditions without symptoms of ataxia, myopathy or cognitive deficiency. A validated HPLC method applying a diode array detector and rac-tocol as internal standard was utilized for that purpose. Furthermore, serum cholesterol levels were determined as well for data normalization. The calculated 2.5-97.5% reference intervals for α-, β/γ- and δ-tocopherols were 24.62-54.67, 0.81-3.69 and 0.29-1.07 μm, respectively, whereas the tocopherol/cholesterol ratios were 5.11-11.27, 0.14-0.72 and 0.06-0.22 μmol/mmol, respectively. The establishment of these reference intervals may improve the diagnostic accuracy of tocopherol measurements in certain neurological conditions with decreased tocopherol levels. Moreover, the current study draws special attention to the possible pitfalls in the complex process of the determination of reference intervals as well, including the selection of study population, the application of internal standard and method validation and the calculation of tocopherol/cholesterol ratios. Copyright © 2017 John Wiley & Sons, Ltd.

  10. A quasiparticle-based multi-reference coupled-cluster method.

    Science.gov (United States)

    Rolik, Zoltán; Kállay, Mihály

    2014-10-07

    The purpose of this paper is to introduce a quasiparticle-based multi-reference coupled-cluster (MRCC) approach. The quasiparticles are introduced via a unitary transformation which allows us to represent a complete active space reference function and other elements of an orthonormal multi-reference (MR) basis in a determinant-like form. The quasiparticle creation and annihilation operators satisfy the fermion anti-commutation relations. On the basis of these quasiparticles, a generalization of the normal-ordered operator products for the MR case can be introduced as an alternative to the approach of Mukherjee and Kutzelnigg [Recent Prog. Many-Body Theor. 4, 127 (1995); Mukherjee and Kutzelnigg, J. Chem. Phys. 107, 432 (1997)]. Based on the new normal ordering any quasiparticle-based theory can be formulated using the well-known diagram techniques. Beyond the general quasiparticle framework we also present a possible realization of the unitary transformation. The suggested transformation has an exponential form where the parameters, holding exclusively active indices, are defined in a form similar to the wave operator of the unitary coupled-cluster approach. The definition of our quasiparticle-based MRCC approach strictly follows the form of the single-reference coupled-cluster method and retains several of its beneficial properties. Test results for small systems are presented using a pilot implementation of the new approach and compared to those obtained by other MR methods.

  11. GMOMETHODS: the European Union database of reference methods for GMO analysis.

    Science.gov (United States)

    Bonfini, Laura; Van den Bulcke, Marc H; Mazzara, Marco; Ben, Enrico; Patak, Alexandre

    2012-01-01

    In order to provide reliable and harmonized information on methods for GMO (genetically modified organism) analysis we have published a database called "GMOMETHODS" that supplies information on PCR assays validated according to the principles and requirements of ISO 5725 and/or the International Union of Pure and Applied Chemistry protocol. In addition, the database contains methods that have been verified by the European Union Reference Laboratory for Genetically Modified Food and Feed in the context of compliance with an European Union legislative act. The web application provides search capabilities to retrieve primers and probes sequence information on the available methods. It further supplies core data required by analytical labs to carry out GM tests and comprises information on the applied reference material and plasmid standards. The GMOMETHODS database currently contains 118 different PCR methods allowing identification of 51 single GM events and 18 taxon-specific genes in a sample. It also provides screening assays for detection of eight different genetic elements commonly used for the development of GMOs. The application is referred to by the Biosafety Clearing House, a global mechanism set up by the Cartagena Protocol on Biosafety to facilitate the exchange of information on Living Modified Organisms. The publication of the GMOMETHODS database can be considered an important step toward worldwide standardization and harmonization in GMO analysis.

  12. MycoKey Round Table Discussions of Future Directions in Research on Chemical Detection Methods, Genetics and Biodiversity of Mycotoxins

    Directory of Open Access Journals (Sweden)

    John F. Leslie

    2018-03-01

    Full Text Available MycoKey, an EU-funded Horizon 2020 project, includes a series of “Roundtable Discussions” to gather information on trending research areas in the field of mycotoxicology. This paper includes summaries of the Roundtable Discussions on Chemical Detection and Monitoring of mycotoxins and on the role of genetics and biodiversity in mycotoxin production. Discussions were managed by using the nominal group discussion technique, which generates numerous ideas and provides a ranking for those identified as the most important. Four questions were posed for each research area, as well as two questions that were common to both discussions. Test kits, usually antibody based, were one major focus of the discussions at the Chemical Detection and Monitoring roundtable because of their many favorable features, e.g., cost, speed and ease of use. The second area of focus for this roundtable was multi-mycotoxin detection protocols and the challenges still to be met to enable these protocols to become methods of choice for regulated mycotoxins. For the genetic and biodiversity group, both the depth and the breadth of trending research areas were notable. For some areas, e.g., microbiome studies, the suggested research questions were primarily of a descriptive nature. In other areas, multiple experimental approaches, e.g., transcriptomics, proteomics, RNAi and gene deletions, are needed to understand the regulation of toxin production and mechanisms underlying successful biological controls. Answers to the research questions will provide starting points for developing acceptable prevention and remediation processes. Forging a partnership between scientists and appropriately-placed communications experts was recognized by both groups as an essential step to communicating risks, while retaining overall confidence in the safety of the food supply and the integrity of the food production chain.

  13. MycoKey Round Table Discussions of Future Directions in Research on Chemical Detection Methods, Genetics and Biodiversity of Mycotoxins

    Science.gov (United States)

    Lattanzio, Veronica; Cary, Jeffrey; Chulze, Sofia N.; Gerardino, Annamaria; Liao, Yu-Cai; Maragos, Chris M.; Meca, Giuseppe; Moretti, Antonio; Munkvold, Gary; Mulè, Giuseppina; Njobeh, Patrick; Pecorelli, Ivan; Pietri, Amedeo; Proctor, Robert H.; Rahayu, Endang S.; Ramírez, Maria L.; Samson, Robert; Stroka, Jörg; Sumarah, Mark; Zhang, Qi; Zhang, Hao; Logrieco, Antonio F.

    2018-01-01

    MycoKey, an EU-funded Horizon 2020 project, includes a series of “Roundtable Discussions” to gather information on trending research areas in the field of mycotoxicology. This paper includes summaries of the Roundtable Discussions on Chemical Detection and Monitoring of mycotoxins and on the role of genetics and biodiversity in mycotoxin production. Discussions were managed by using the nominal group discussion technique, which generates numerous ideas and provides a ranking for those identified as the most important. Four questions were posed for each research area, as well as two questions that were common to both discussions. Test kits, usually antibody based, were one major focus of the discussions at the Chemical Detection and Monitoring roundtable because of their many favorable features, e.g., cost, speed and ease of use. The second area of focus for this roundtable was multi-mycotoxin detection protocols and the challenges still to be met to enable these protocols to become methods of choice for regulated mycotoxins. For the genetic and biodiversity group, both the depth and the breadth of trending research areas were notable. For some areas, e.g., microbiome studies, the suggested research questions were primarily of a descriptive nature. In other areas, multiple experimental approaches, e.g., transcriptomics, proteomics, RNAi and gene deletions, are needed to understand the regulation of toxin production and mechanisms underlying successful biological controls. Answers to the research questions will provide starting points for developing acceptable prevention and remediation processes. Forging a partnership between scientists and appropriately-placed communications experts was recognized by both groups as an essential step to communicating risks, while retaining overall confidence in the safety of the food supply and the integrity of the food production chain. PMID:29494529

  14. Matrix pencil method-based reference current generation for shunt active power filters

    DEFF Research Database (Denmark)

    Terriche, Yacine; Golestan, Saeed; Guerrero, Josep M.

    2018-01-01

    response and works well under distorted and unbalanced voltage. Moreover, the proposed method can estimate the voltage phase accurately; this property enables the algorithm to compensate for both power factor and current unbalance. The effectiveness of the proposed method is verified using simulation...... are using the discrete Fourier transform (DFT) in the frequency domain or the instantaneous p–q theory and the synchronous reference frame in the time domain. The DFT, however, suffers from the picket-fence effect and spectral leakage. On the other hand, the DFT takes at least one cycle of the nominal...... frequency. The time-domain methods show a weakness under voltage distortion, which requires prior filtering techniques. The aim of this study is to present a fast yet effective method for generating the RCC for SAPFs. The proposed method, which is based on the matrix pencil method, has a fast dynamic...

  15. Determining experimentally the parameters of the unsteady thermal behaviour of homogeneously layered walls by the reference plates method

    International Nuclear Information System (INIS)

    Beron, Rodolphe

    1988-01-01

    In this work, we introduce an experimental determination method of parameters which are characteristics of the transfer functions of walls in buildings by the use of an easy equipment which use needs no significant constraint. This method called 'reference plates method' is based on the working out of the thermo-grams which result from any thermal perturbation. The first part of our work deals with the theoretical development of the methods of working out the measures used for both single-Iayered and multi-layered walls. The second part discusses the applying of the method on single-Iayered sample. The values of thermophysical characteristics of the wall is based on the working out of the heat equation written in terms an integral transformation which we take as Laplace's transformation. The case of multi-Iayered wall which we discuss in the third part, lead to the determination of 'z transforms coefficients' of the transfer functions of the studied wall. In addition to the theoretical study, we analyse the results of prospective experiments in the fourth part of our work and show the usefulness of such a measurement method. The last part is devoted to the presentation of the application of our work to the determination of thermal parameters of more general wall's configurations. (author) [fr

  16. Verification of chemistry reference ranges using a simple method in sub-Saharan Africa

    Directory of Open Access Journals (Sweden)

    Irith De Baetselier

    2016-10-01

    Full Text Available Background: Chemistry safety assessments are interpreted by using chemistry reference ranges (CRRs. Verification of CRRs is time consuming and often requires a statistical background. Objectives: We report on an easy and cost-saving method to verify CRRs. Methods: Using a former method introduced by Sigma Diagnostics, three study sites in sub- Saharan Africa, Bondo, Kenya, and Pretoria and Bloemfontein, South Africa, verified the CRRs for hepatic and renal biochemistry assays performed during a clinical trial of HIV antiretroviral pre-exposure prophylaxis. The aspartate aminotransferase/alanine aminotransferase, creatinine and phosphorus results from 10 clinically-healthy participants at the screening visit were used. In the event the CRRs did not pass the verification, new CRRs had to be calculated based on 40 clinically-healthy participants. Results: Within a few weeks, the study sites accomplished verification of the CRRs without additional costs. The aspartate aminotransferase reference ranges for the Bondo, Kenya site and the alanine aminotransferase reference ranges for the Pretoria, South Africa site required adjustment. The phosphorus CRR passed verification and the creatinine CRR required adjustment at every site. The newly-established CRR intervals were narrower than the CRRs used previously at these study sites due to decreases in the upper limits of the reference ranges. As a result, more toxicities were detected. Conclusion: To ensure the safety of clinical trial participants, verification of CRRs should be standard practice in clinical trials conducted in settings where the CRR has not been validated for the local population. This verification method is simple, inexpensive, and can be performed by any medical laboratory.

  17. Precision and Accuracy of k0-NAA Method for Analysis of Multi Elements in Reference Samples

    International Nuclear Information System (INIS)

    Sri-Wardani

    2004-01-01

    Accuracy and precision of k 0 -NAA method could determine in the analysis of multi elements contained in reference samples. The analyzed results of multi elements in SRM 1633b sample were obtained with optimum results in bias of 20% but it is in a good accuracy and precision. The analyzed results of As, Cd and Zn in CCQM-P29 rice flour sample were obtained with very good result in bias of 0.5 - 5.6%. (author)

  18. The complementary use of radioanalytical methods and trace analysis methods for the characterisation of environmental IAEA reference materials

    International Nuclear Information System (INIS)

    De Regge, P.; Burns, K.; Campbell, M.; Makarewicz, M.; Markowicz, A.; Mattiuzzi, M.; Tajani, A.; Toervenyi, A.; Zeiller, E.

    2001-01-01

    The IAEA laboratories have access to both nuclear analytical methods and conventional instrumental methods for trace analysis for the characterisation of its environmental and biological reference materials. A technical concept integrating the homogeneity data, the recommended test portion mass and the uncertainty on the trace element concentrations is explored using a combination of INAA, XRF, ICP-MS, ICP-AES, and AAS. The above approach is illustrated by selected examples of reference materials currently under evaluation for their trace element content. They include some or all of the following elements Al, As, Br, Ca, Cd, Co, Cr, Cs, Cu, Fe, Hg, K, Mg, Mn, Mo, Na, Ni, Pb, Rb, Se, Sr, Th, U, Zn in environmental biomonitor organisms (lichen, algae) and air dust filters. (author)

  19. Identification of reliable gridded reference data for statistical downscaling methods in Alberta

    Science.gov (United States)

    Eum, H. I.; Gupta, A.

    2017-12-01

    Climate models provide essential information to assess impacts of climate change at regional and global scales. However, statistical downscaling methods have been applied to prepare climate model data for various applications such as hydrologic and ecologic modelling at a watershed scale. As the reliability and (spatial and temporal) resolution of statistically downscaled climate data mainly depend on a reference data, identifying the most reliable reference data is crucial for statistical downscaling. A growing number of gridded climate products are available for key climate variables which are main input data to regional modelling systems. However, inconsistencies in these climate products, for example, different combinations of climate variables, varying data domains and data lengths and data accuracy varying with physiographic characteristics of the landscape, have caused significant challenges in selecting the most suitable reference climate data for various environmental studies and modelling. Employing various observation-based daily gridded climate products available in public domain, i.e. thin plate spline regression products (ANUSPLIN and TPS), inverse distance method (Alberta Townships), and numerical climate model (North American Regional Reanalysis) and an optimum interpolation technique (Canadian Precipitation Analysis), this study evaluates the accuracy of the climate products at each grid point by comparing with the Adjusted and Homogenized Canadian Climate Data (AHCCD) observations for precipitation, minimum and maximum temperature over the province of Alberta. Based on the performance of climate products at AHCCD stations, we ranked the reliability of these publically available climate products corresponding to the elevations of stations discretized into several classes. According to the rank of climate products for each elevation class, we identified the most reliable climate products based on the elevation of target points. A web-based system

  20. A quantitative discussion on the assessment of power supply technologies: DEA (data envelopment analysis) and SAW (simple additive weighting) as complementary methods for the “Grammar”

    International Nuclear Information System (INIS)

    Shakouri, Hamed G.; Nabaee, Mahdis; Aliakbarisani, Sajad

    2014-01-01

    The growing concern about the negative effects of fossil fuels on the environment, and the limited resources of them have forced more intensive use of other energy sources. In absence of sufficient economically feasible renewable energies, nuclear power may play essential role in this field. Recently, the advantages and disadvantages of nuclear power and fossil fuels regarding their efficiencies have been attracted researchers' interest. This paper discusses on the findings from “A Grammar for assessing the performance of power supply systems: comparing nuclear energy to fossil energy” (Diaz-Maurin F, Giampietro M. 2013). Although the “Grammar” is a very valuable approach, it can be accomplished by using helpful quantitative methods. In this discussion, we apply quantitative decision-making approaches to compare the same fossil fuel (coal) power plants with nuclear power plants. Economic variables are also taken into consideration. The DEA (data envelopment analysis) and SAW (simple additive weighting) are the methods applied. Results confirm the results of the reference paper in most cases and show that the fossil fuel power plants with CCS (carbon capture and storage) are slightly more efficient than nuclear power plants. However, selection of input and output variables is disputable. Assuming job creation as a desired output can change the ranking results. - Highlights: • A numeric decision making approach is proposed to facilitate assessment of technologies introduced as a “Grammar”. • Two different methods are chosen (SAW and DEA) since the results obtained for ranking may differ with different methods. • We propose to use the original fractional objective function of DEA with equal weightings applied for the attributes. • Proper combinations of both input and output attributes including economic variables are discussed. • The attributes for assessment of the technologies differ from different viewpoints. Labor force and costs are simple

  1. Practicing the practice: Learning to guide elementary science discussions in a practice-oriented science methods course

    Science.gov (United States)

    Shah, Ashima Mathur

    University methods courses are often criticized for telling pre-service teachers, or interns, about the theories behind teaching instead of preparing them to actually enact teaching. Shifting teacher education to be more "practice-oriented," or to focus more explicitly on the work of teaching, is a current trend for re-designing the way we prepare teachers. This dissertation addresses the current need for research that unpacks the shift to more practice-oriented approaches by studying the content and pedagogical approaches in a practice-oriented, masters-level elementary science methods course (n=42 interns). The course focused on preparing interns to guide science classroom discussions. Qualitative data, such as video records of course activities and interns' written reflections, were collected across eight course sessions. Codes were applied at the sentence and paragraph level and then grouped into themes. Five content themes were identified: foregrounding student ideas and questions, steering discussion toward intended learning goals, supporting students to do the cognitive work, enacting teacher role of facilitator, and creating a classroom culture for science discussions. Three pedagogical approach themes were identified. First, the teacher educators created images of science discussions by modeling and showing videos of this practice. They also provided focused teaching experiences by helping interns practice the interactive aspects of teaching both in the methods classroom and with smaller groups of elementary students in schools. Finally, they structured the planning and debriefing phases of teaching so interns could learn from their teaching experiences and prepare well for future experiences. The findings were analyzed through the lens of Grossman and colleagues' framework for teaching practice (2009) to reveal how the pedagogical approaches decomposed, represented, and approximated practice throughout course activities. Also, the teacher educators

  2. THE EFFECTIVENESS OF CASE BASED DISCUSSION AS A VALID PROBLEM BASED LEARNING METHOD IN ANAESTHESIA POSTGRADUATE TEACHING

    Directory of Open Access Journals (Sweden)

    Melveetil S

    2015-11-01

    Full Text Available : CONTEXT: Anaesthesia is a branch of medicine which allows only a very narrow margin of error. Anaesthesia post-graduate (PG teaching with problem-based learning (PBL enhances the critical thinking and problem-solving skills among the students .Among the different problem based learning methods case based discussions (CBD are most widely practiced out of all in anaesthesia PG teaching. METHODS AND MATERIAL: An anonymous questionnaire based, crosssectional survey among 37 anaesthesia residents from two medical institutions in North Kerala, India was conducted. The present survey was designed to assess the effectiveness of case based discussions in anaesthesia PG teaching by assessing the student’s satisfaction with CBD and the suggested modifications if any to improve the current status of teaching. RESULTS AND CONCLUSIONS: The CBD as a part of PBL in anesthesia PG teaching in our set up lacks many important aspects of PBL such as formulation of objectives, facilitation skills, communication on direction of PBL and supplementation of inadequacies. A broader, strict and organized implementation of PBL incorporating the key elements of PBL needs emphasis in PG teaching curriculum. Facilitation skill development programs needs motivation and encouragement from the perspective of the academic administrators.

  3. Improvements in the equipment for determination of Kr-85 with the reference method

    International Nuclear Information System (INIS)

    Heras Iniquez, M.C.; Perez Garcia, M.M.

    1983-01-01

    A new equipment for Kr-85 separation and their cryogenic chromatographic concentration is described, which presents some advantages respect the equipment used as reference. The new apparatus, made with metallic elements, is based on the method of concentration and separation previously described but presents easier control, faster chromatographic separations and without loosed of efficiency and reproducibility that the previous one. The concentration and separation procedure for Kr-85 and a comparative study between both apparatus is described. Also the efficiency of the method is obtained experimentally. (Author)

  4. Method of collective variables with reference system for the grand canonical ensemble

    International Nuclear Information System (INIS)

    Yukhnovskii, I.R.

    1989-01-01

    A method of collective variables with special reference system for the grand canonical ensemble is presented. An explicit form is obtained for the basis sixth-degree measure density needed to describe the liquid-gas phase transition. Here the author presents the fundamentals of the method, which are as follows: (1) the functional form for the partition function in the grand canonical ensemble; (2) derivation of thermodynamic relations for the coefficients of the Jacobian; (3) transition to the problem on an adequate lattice; and (4) obtaining of the explicit form for the functional of the partition function

  5. Verification of chemistry reference ranges using a simple method in sub-Saharan Africa.

    Science.gov (United States)

    De Baetselier, Irith; Taylor, Douglas; Mandala, Justin; Nanda, Kavita; Van Campenhout, Christel; Agingu, Walter; Madurai, Lorna; Barsch, Eva-Maria; Deese, Jennifer; Van Damme, Lut; Crucitti, Tania

    2016-01-01

    Chemistry safety assessments are interpreted by using chemistry reference ranges (CRRs). Verification of CRRs is time consuming and often requires a statistical background. We report on an easy and cost-saving method to verify CRRs. Using a former method introduced by Sigma Diagnostics, three study sites in sub-Saharan Africa, Bondo, Kenya, and Pretoria and Bloemfontein, South Africa, verified the CRRs for hepatic and renal biochemistry assays performed during a clinical trial of HIV antiretroviral pre-exposure prophylaxis. The aspartate aminotransferase/alanine aminotransferase, creatinine and phosphorus results from 10 clinically-healthy participants at the screening visit were used. In the event the CRRs did not pass the verification, new CRRs had to be calculated based on 40 clinically-healthy participants. Within a few weeks, the study sites accomplished verification of the CRRs without additional costs. The aspartate aminotransferase reference ranges for the Bondo, Kenya site and the alanine aminotransferase reference ranges for the Pretoria, South Africa site required adjustment. The phosphorus CRR passed verification and the creatinine CRR required adjustment at every site. The newly-established CRR intervals were narrower than the CRRs used previously at these study sites due to decreases in the upper limits of the reference ranges. As a result, more toxicities were detected. To ensure the safety of clinical trial participants, verification of CRRs should be standard practice in clinical trials conducted in settings where the CRR has not been validated for the local population. This verification method is simple, inexpensive, and can be performed by any medical laboratory.

  6. ANSI/ASHRAE/IES Standard 90.1-2010 Performance Rating Method Reference Manual

    Energy Technology Data Exchange (ETDEWEB)

    Goel, Supriya [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Rosenberg, Michael I. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-05-01

    This document is intended to be a reference manual for the Appendix G Performance Rating Method (PRM) of ANSI/ASHRAE/IES Standard 90.1- 2010 (Standard 90.1-2010).The PRM is used for rating the energy efficiency of commercial and high-rise residential buildings with designs that exceed the requirements of Standard 90.1. The procedures and processes described in this manual are designed to provide consistency and accuracy by filling in gaps and providing additional details needed by users of the PRM. It should be noted that this document is created independently from ASHRAE and SSPC 90.1 and is not sanctioned nor approved by either of those entities . Potential users of this manual include energy modelers, software developers and implementers of “beyond code” energy programs. Energy modelers using ASHRAE Standard 90.1-2010 for beyond code programs can use this document as a reference manual for interpreting requirements of the Performance Rating method. Software developers, developing tools for automated creation of the baseline model can use this reference manual as a guideline for developing the rules for the baseline model.

  7. Reference voltage calculation method based on zero-sequence component optimisation for a regional compensation DVR

    Science.gov (United States)

    Jian, Le; Cao, Wang; Jintao, Yang; Yinge, Wang

    2018-04-01

    This paper describes the design of a dynamic voltage restorer (DVR) that can simultaneously protect several sensitive loads from voltage sags in a region of an MV distribution network. A novel reference voltage calculation method based on zero-sequence voltage optimisation is proposed for this DVR to optimise cost-effectiveness in compensation of voltage sags with different characteristics in an ungrounded neutral system. Based on a detailed analysis of the characteristics of voltage sags caused by different types of faults and the effect of the wiring mode of the transformer on these characteristics, the optimisation target of the reference voltage calculation is presented with several constraints. The reference voltages under all types of voltage sags are calculated by optimising the zero-sequence component, which can reduce the degree of swell in the phase-to-ground voltage after compensation to the maximum extent and can improve the symmetry degree of the output voltages of the DVR, thereby effectively increasing the compensation ability. The validity and effectiveness of the proposed method are verified by simulation and experimental results.

  8. Comparison of analytical methods for the determination of histamine in reference canned fish samples

    Science.gov (United States)

    Jakšić, S.; Baloš, M. Ž.; Mihaljev, Ž.; Prodanov Radulović, J.; Nešić, K.

    2017-09-01

    Two screening methods for histamine in canned fish, an enzymatic test and a competitive direct enzyme-linked immunosorbent assay (CD-ELISA), were compared with the reversed-phase liquid chromatography (RP-HPLC) standard method. For enzymatic and CD-ELISA methods, determination was conducted according to producers’ manuals. For RP-HPLC, histamine was derivatized with dansyl-chloride, followed by RP-HPLC and diode array detection. Results of analysis of canned fish, supplied as reference samples for proficiency testing, showed good agreement when histamine was present at higher concentrations (above 100 mg kg-1). At a lower level (16.95 mg kg-1), the enzymatic test produced some higher results. Generally, analysis of four reference samples according to CD-ELISA and RP-HPLC showed good agreement for histamine determination (r=0.977 in concentration range 16.95-216 mg kg-1) The results show that the applied enzymatic test and CD-ELISA appeared to be suitable screening methods for the determination of histamine in canned fish.

  9. Built-up index methods and their applications for urban extraction from Sentinel 2A satellite data: discussion.

    Science.gov (United States)

    Valdiviezo-N, Juan C; Téllez-Quiñones, Alejandro; Salazar-Garibay, Adan; López-Caloca, Alejandra A

    2018-01-01

    Several built-up indices have been proposed in the literature in order to extract the urban sprawl from satellite data. Given their relative simplicity and easy implementation, such methods have been widely adopted for urban growth monitoring. Previous research has shown that built-up indices are sensitive to different factors related to image resolution, seasonality, and study area location. Also, most of them confuse urban surfaces with bare soil and barren land covers. By gathering the existing built-up indices, the aim of this paper is to discuss some of their advantages, difficulties, and limitations. In order to illustrate our study, we provide some application examples using Sentinel 2A data.

  10. Evaluation of different methods to estimate daily reference evapotranspiration in ungauged basins in Southern Brazil

    Science.gov (United States)

    Ribeiro Fontoura, Jessica; Allasia, Daniel; Herbstrith Froemming, Gabriel; Freitas Ferreira, Pedro; Tassi, Rutineia

    2016-04-01

    Evapotranspiration is a key process of hydrological cycle and a sole term that links land surface water balance and land surface energy balance. Due to the higher information requirements of the Penman-Monteith method and the existing data uncertainty, simplified empirical methods for calculating potential and actual evapotranspiration are widely used in hydrological models. This is especially important in Brazil, where the monitoring of meteorological data is precarious. In this study were compared different methods for estimating evapotranspiration for Rio Grande do Sul, the Southernmost State of Brazil, aiming to suggest alternatives to the recommended method (Penman-Monteith-FAO 56) for estimate daily reference evapotranspiration (ETo) when meteorological data is missing or not available. The input dataset included daily and hourly-observed data from conventional and automatic weather stations respectively maintained by the National Weather Institute of Brazil (INMET) from the period of 1 January 2007 to 31 January 2010. Dataset included maximum temperature (Tmax, °C), minimum temperature (Tmin, °C), mean relative humidity (%), wind speed at 2 m height (u2, m s-1), daily solar radiation (Rs, MJ m- 2) and atmospheric pressure (kPa) that were grouped at daily time-step. Was tested the Food and Agriculture Organization of the United Nations (FAO) Penman-Monteith method (PM) at its full form, against PM assuming missing several variables not normally available in Brazil in order to calculate daily reference ETo. Missing variables were estimated as suggested in FAO56 publication or from climatological means. Furthermore, PM was also compared against the following simplified empirical methods: Hargreaves-Samani, Priestley-Taylor, Mccloud, McGuiness-Bordne, Romanenko, Radiation-Temperature, Tanner-Pelton. The statistical analysis indicates that even if just Tmin and Tmax are available, it is better to use PM estimating missing variables from syntetic data than

  11. Performance of different methods for reference evapotranspiration estimation in Jaíba, Brazil

    Directory of Open Access Journals (Sweden)

    Gustavo H. da Silva

    Full Text Available ABSTRACT FAO Penman-Monteith (FO-PM is considered the standard method for the estimation of reference evapotranspiration (ET0 but requires various meteorological data, which are often not available. The objective of this work was to evaluate the performance of the FAO-PM method with limited meteorological data and other methods as alternatives to estimate ET0 in Jaíba-MG. The study used daily meteorological data from 2007 to 2016 of the National Institute of Meteorology’s station. Daily ET0 values were randomized, and 70% of these were used to determine the calibration parameters of the ET0 for the equations of each method under study. The remaining data were used to test the calibration against the standard method. Performance evaluation was based on Willmott’s index of agreement, confidence coefficient and root-mean-square error. When one meteorological variable was missing, either solar radiation, relative air humidity or wind speed, or in the simultaneous absence of wind speed and relative air humidity, the FAO-PM method showed the best performances and, therefore, was recommended for Jaíba. The FAO-PM method with two missing variables, one of them being solar radiation, showed intermediate performance. Methods that used only air temperature data are not recommended for the region.

  12. Performance of NAA methods in an International Interlaboratory Reference Material Characterization Campaign

    International Nuclear Information System (INIS)

    Ihnat, M.

    2000-01-01

    An extensive database of analytical results from a recent biological matrix Reference Material Characterization Campaign permitted an intercomparison of the performances of various methods among each other and with 'true' best estimate concentration values established for these materials. Six different variants of neutron activation analysis (NAA) methods were employed including: instrumental neutron activation analysis, instrumental neutron activation analysis with acid digestion, neutron activation analysis with radiochemical separation, neutron capture prompt gamma activation analysis, epithermal instrumental neutron activation analysis, and neutron activation analysis with preconcentration. The precision and accuracy performance of NAA-based analytical methods are compared with three other major techniques, atomic absorption spectrometry (AAS), atomic emission spectrometry (AES) and mass spectrometry (MS) for 28 elements in 10 natural matrix materials. (author)

  13. Standard Test Method for Electrical Performance of Photovoltaic Cells Using Reference Cells Under Simulated Sunlight

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2009-01-01

    1.1 This test method covers the determination of the electrical performance of a photovoltaic cell under simulated sunlight by means of a calibrated reference cell procedure. 1.2 Electrical performance measurements are reported with respect to a select set of standard reporting conditions (SRC) (see Table 1) or to user-specified conditions. 1.2.1 The SRC or user-specified conditions include the cell temperature, the total irradiance, and the reference spectral irradiance distribution. 1.3 This test method is applicable only to photovoltaic cells with a linear response over the range of interest. 1.4 The cell parameters determined by this test method apply only at the time of test, and imply no past or future performance level. 1.5 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard. 1.6 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this s...

  14. Repositioning reference new methods and new services for a new age

    CERN Document Server

    Rozaklis, Lillian

    2014-01-01

    Repositioning Reference reimagines reference services in libraries and information organizations and the role of reference librarians, taking into account rapid developments in technology and information-specific services in non-library sectors.

  15. Deviation of landmarks in accordance with methods of establishing reference planes in three-dimensional facial CT evaluation.

    Science.gov (United States)

    Yoon, Kaeng Won; Yoon, Suk-Ja; Kang, Byung-Cheol; Kim, Young-Hee; Kook, Min Suk; Lee, Jae-Seo; Palomo, Juan Martin

    2014-09-01

    This study aimed to investigate the deviation of landmarks from horizontal or midsagittal reference planes according to the methods of establishing reference planes. Computed tomography (CT) scans of 18 patients who received orthodontic and orthognathic surgical treatment were reviewed. Each CT scan was reconstructed by three methods for establishing three orthogonal reference planes (namely, the horizontal, midsagittal, and coronal reference planes). The horizontal (bilateral porions and bilateral orbitales) and midsagittal (crista galli, nasion, prechiasmatic point, opisthion, and anterior nasal spine) landmarks were identified on each CT scan. Vertical deviation of the horizontal landmarks and horizontal deviation of the midsagittal landmarks were measured. The porion and orbitale, which were not involved in establishing the horizontal reference plane, were found to deviate vertically from the horizontal reference plane in the three methods. The midsagittal landmarks, which were not used for the midsagittal reference plane, deviated horizontally from the midsagittal reference plane in the three methods. In a three-dimensional facial analysis, the vertical and horizontal deviations of the landmarks from the horizontal and midsagittal reference planes could vary depending on the methods of establishing reference planes.

  16. Deviation of landmarks in accordance with methods of establishing reference planes in three-dimensional facial CT evaluation

    International Nuclear Information System (INIS)

    Yoon, Kaeng Won; Yoon, Suk Ja; Kang, Byung Cheol; Kook, Min Suk; Lee, Jae Seo; Kim, Young Hee; Palomo, Juan Martin

    2014-01-01

    This study aimed to investigate the deviation of landmarks from horizontal or midsagittal reference planes according to the methods of establishing reference planes. Computed tomography (CT) scans of 18 patients who received orthodontic and orthognathic surgical treatment were reviewed. Each CT scan was reconstructed by three methods for establishing three orthogonal reference planes (namely, the horizontal, midsagittal, and coronal reference planes). The horizontal (bilateral porions and bilateral orbitales) and midsagittal (crista galli, nasion, prechiasmatic point, opisthion, and anterior nasal spine) landmarks were identified on each CT scan. Vertical deviation of the horizontal landmarks and horizontal deviation of the midsagittal landmarks were measured. The porion and orbitale, which were not involved in establishing the horizontal reference plane, were found to deviate vertically from the horizontal reference plane in the three methods. The midsagittal landmarks, which were not used for the midsagittal reference plane, deviated horizontally from the midsagittal reference plane in the three methods. In a three-dimensional facial analysis, the vertical and horizontal deviations of the landmarks from the horizontal and midsagittal reference planes could vary depending on the methods of establishing reference planes.

  17. Deviation of landmarks in accordance with methods of establishing reference planes in three-dimensional facial CT evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Kaeng Won; Yoon, Suk Ja; Kang, Byung Cheol; Kook, Min Suk; Lee, Jae Seo [School of Dentistry, Dental Science Research Institute, Chonnam National University, Gwangju (Korea, Republic of); Kim, Young Hee [Dept. of Oral and Maxillofacial Radiology, Hallym University Sacred Heart Hospital, Anyang (Korea, Republic of); Palomo, Juan Martin [Dept. of Orthodontics, School of Dental Medicine, Case Western Reserve University, Cleveland (Korea, Republic of)

    2014-09-15

    This study aimed to investigate the deviation of landmarks from horizontal or midsagittal reference planes according to the methods of establishing reference planes. Computed tomography (CT) scans of 18 patients who received orthodontic and orthognathic surgical treatment were reviewed. Each CT scan was reconstructed by three methods for establishing three orthogonal reference planes (namely, the horizontal, midsagittal, and coronal reference planes). The horizontal (bilateral porions and bilateral orbitales) and midsagittal (crista galli, nasion, prechiasmatic point, opisthion, and anterior nasal spine) landmarks were identified on each CT scan. Vertical deviation of the horizontal landmarks and horizontal deviation of the midsagittal landmarks were measured. The porion and orbitale, which were not involved in establishing the horizontal reference plane, were found to deviate vertically from the horizontal reference plane in the three methods. The midsagittal landmarks, which were not used for the midsagittal reference plane, deviated horizontally from the midsagittal reference plane in the three methods. In a three-dimensional facial analysis, the vertical and horizontal deviations of the landmarks from the horizontal and midsagittal reference planes could vary depending on the methods of establishing reference planes.

  18. Tentative reference method for measurement of tritium in environmental waters. Environmental monitoring series

    International Nuclear Information System (INIS)

    1975-12-01

    A tentative reference method for the measurement of tritium in potable and nonpotable environmental water is described. Water samples are treated with sodium hydroxide and potassium permanganate and then a water fraction is separated from interferences by distillation. Two distillation procedures are described, a simple aqueous distillation for samples from potable water sources, and an aqueous-azeotropic-benzene distillation for nonpotable water sources. Alliquots of a designated distillate fraction are measured for tritium activity by liquid scintillation detection. Distillation recovery and counting efficiency factors are determined with tritium standards. Results are reported in picocuries per milliliter

  19. Summary discussions

    International Nuclear Information System (INIS)

    Ritchie, R.H.

    1982-01-01

    Remarks intended to highlight topics of importance for future research were made by three of the participants at the conclusion of the Seminar. A brief listing is given of topics discussed by each of these rapporteurs

  20. Methods for definition of reference conditions for a repository site taking long-term environmental change into account

    Energy Technology Data Exchange (ETDEWEB)

    Ikonen, A.T.K. [Environmental Research and Assessment EnviroCase, Ltd. (Finland)

    2014-07-01

    In a few countries, programmes for disposal of spent nuclear fuel have proceeded into a site-specific phase, and the number of low- and intermediate-level nuclear waste repositories requiring updated state-of-the-art long-term safety assessments is considerable. In this contribution, the approach employed in the Finnish spent fuel disposal programme is analysed and used as an example for a more general methodology for defining reference surface conditions for a site, e.g. to guide selection of representative input data to safety assessments, using spatio-temporal analogues so that long-term environmental changes are taken into account. The contribution incorporates also elements from discussions in the IAEA EMRAS II and MODARIA working groups on addressing the environmental change in the assessments. The legacy of the earlier BIOMASS project is also recognised. Broadly, the methods to be presented include identification of similarity factors (e.g. geological, biological and climate regimes) upon which a reference area can be delineated. Within the reference area, characteristic lines of development and biotopes are identified and described, and these are then used to guide further research and application of literature data to iteratively accumulate adequate understanding of the site conditions and relevant processes at the present and in the future (by projecting further the past and present development lines and biotopes). In this iterative approach, also the intensity of research efforts can be adjusted with the stage of the repository programme, as will be discussed in the complete contribution. Document available in abstract form only. (authors)

  1. Assessment of air quality microsensors versus reference methods: The EuNetAir joint exercise

    Science.gov (United States)

    Borrego, C.; Costa, A. M.; Ginja, J.; Amorim, M.; Coutinho, M.; Karatzas, K.; Sioumis, Th.; Katsifarakis, N.; Konstantinidis, K.; De Vito, S.; Esposito, E.; Smith, P.; André, N.; Gérard, P.; Francis, L. A.; Castell, N.; Schneider, P.; Viana, M.; Minguillón, M. C.; Reimringer, W.; Otjes, R. P.; von Sicard, O.; Pohle, R.; Elen, B.; Suriano, D.; Pfister, V.; Prato, M.; Dipinto, S.; Penza, M.

    2016-12-01

    The 1st EuNetAir Air Quality Joint Intercomparison Exercise organized in Aveiro (Portugal) from 13th-27th October 2014, focused on the evaluation and assessment of environmental gas, particulate matter (PM) and meteorological microsensors, versus standard air quality reference methods through an experimental urban air quality monitoring campaign. The IDAD-Institute of Environment and Development Air Quality Mobile Laboratory was placed at an urban traffic location in the city centre of Aveiro to conduct continuous measurements with standard equipment and reference analysers for CO, NOx, O3, SO2, PM10, PM2.5, temperature, humidity, wind speed and direction, solar radiation and precipitation. The comparison of the sensor data generated by different microsensor-systems installed side-by-side with reference analysers, contributes to the assessment of the performance and the accuracy of microsensor-systems in a real-world context, and supports their calibration and further development. The overall performance of the sensors in terms of their statistical metrics and measurement profile indicates significant differences in the results depending on the platform and on the sensors considered. In terms of pollutants, some promising results were observed for O3 (r2: 0.12-0.77), CO (r2: 0.53-0.87), and NO2 (r2: 0.02-0.89). For PM (r2: 0.07-0.36) and SO2 (r2: 0.09-0.20) the results show a poor performance with low correlation coefficients between the reference and microsensor measurements. These field observations under specific environmental conditions suggest that the relevant microsensor platforms, if supported by the proper post processing and data modelling tools, have enormous potential for new strategies in air quality control.

  2. ICP-MS determination of boron: method optimization during preparation of graphite reference material for boron

    International Nuclear Information System (INIS)

    Granthali, S.K.; Shailaja, P.P.; Mainsha, V.; Venkatesh, K.; Kallola, K.S.; Sanjukta, A.K.

    2017-01-01

    Graphite finds widespread use in nuclear reactors as moderator, reflector, and fuel fabricating components because of its thermal stability and integrity. The manufacturing process consists of various mixing, moulding and baking operations followed by heat-treatment between 2500 °C and 3000 °C. The high temperature treatment is required to drive the amorphous carbon-to-graphite phase transformation. Since synthetic graphite is processed at high temperature, impurity concentrations in the precursor carbon get significantly reduced due to volatilization. However boron may might partly gets converted into boron carbide at high temperatures in the carbon environment of graphite and remains stable (B_4C: boiling point 3500 °C) in the matrix. Literature survey reveals the use of various methods for determination of boron. Previously we have developed a method for determination of boron in graphite electrodes using inductively coupled plasma mass spectrometry (ICP-MS). The method involves removal of graphite matrix by ignition of the sample at 800°C in presence of saturated barium hydroxide solution to prevent the loss of boron. Here we are reporting a modification in the method by using calcium carbonate in place of barium hydroxide and using beryllium (Be) as an internal standard, which resulted in a better precession. The method was validated by spike recovery experiments as well as using another technique viz. Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES). The modified method was applied in evaluation of boron concentration in the graphite reference material prepared

  3. Multivariate methods for analysis of environmental reference materials using laser-induced breakdown spectroscopy

    Directory of Open Access Journals (Sweden)

    Shikha Awasthi

    2017-06-01

    Full Text Available Analysis of emission from laser-induced plasma has a unique capability for quantifying the major and minor elements present in any type of samples under optimal analysis conditions. Chemometric techniques are very effective and reliable tools for quantification of multiple components in complex matrices. The feasibility of laser-induced breakdown spectroscopy (LIBS in combination with multivariate analysis was investigated for the analysis of environmental reference materials (RMs. In the present work, different (Certified/Standard Reference Materials of soil and plant origin were analyzed using LIBS and the presence of Al, Ca, Mg, Fe, K, Mn and Si were identified in the LIBS spectra of these materials. Multivariate statistical methods (Partial Least Square Regression and Partial Least Square Discriminant Analysis were employed for quantitative analysis of the constituent elements using the LIBS spectral data. Calibration models were used to predict the concentrations of the different elements of test samples and subsequently, the concentrations were compared with certified concentrations to check the authenticity of models. The non-destructive analytical method namely Instrumental Neutron Activation Analysis (INAA using high flux reactor neutrons and high resolution gamma-ray spectrometry was also used for intercomparison of results of two RMs by LIBS.

  4. Standard Reference Test Method for Making Potentiostatic and Potentiodynamic Anodic Polarization Measurements

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2004-01-01

    1.1 This test method covers an experimental procedure for checking experimental technique and instrumentation. If followed, this test method will provide repeatable potentiostatic and potentiodynamic anodic polarization measurements that will reproduce data determined by others at other times and in other laboratories provided all laboratories are testing reference samples from the same lot of Type 430 stainless steel. 1.2 Values stated in SI units are to be regarded as the standard. Inch-pound units given in parentheses are for information only. 1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

  5. Panel discussion

    International Nuclear Information System (INIS)

    Anon.

    1980-01-01

    The panel discussion at the 10th Allianz Forum on 'Technology and Insurance' dealt with the following topics: New technologies: energy conversion (coal, petroleum, natural gas, nuclear energy, solar energy); infrastructure (transport, data processing); basic products (metallic materials, chemical products, pharmaceutical products); integrated products (microprocessors, production line machines) as well as new risks: political; general economic (financing, market structure); insurance-related, dangers to persons and property; reduction of risks. (orig.) [de

  6. Measurement of strontium-89 and strontium-90 in environmental waters. A tentative reference method

    International Nuclear Information System (INIS)

    1976-03-01

    A tentative reference method for the measurement of 89 Sr and 90 Sr in environmental waters is described. Samples of environmental water sources are collected, preserved with acid-strontium carrier, and analyzed for 89 Sr and/or 90 Sr. The isotopes are separated from the sample water by precipitating with stable strontium carrier as carbonate. The strontium carbonate is dissolved, 90 Sr separated, the strontium reprecipitated as carbonate, filtered, and counted for the combined 89 Sr and 90 Sr activity. The 90 y is allowed to grow in from the 90 y activity; the strontium carbonate is redissolved; the 90 y is separated, precipitated, and counted for the 90 Sr determination. The 89 Sr activity is then determined by difference of the total 89 Sr and 90 y and the separate 90 Sr activities. Recoveries are determined from the added and found (recovered) strontium carrier. Counting efficiencies are determined with prepared standard reference samples. Results are reported in pCi/liter

  7. Preparation and evaluation of reference materials for accountancy analysis. (1) Preparation and evaluation method

    International Nuclear Information System (INIS)

    Takamatsu, Mai; Kacchi, Tomokazu; Murakami, Toshiki; Ai, Hironobu; Sumi, Mika; Abe, Katsuo; Kageyama, Tomio; Nakazawa, Hiroaki

    2009-01-01

    Isotope dilution mass spectrometry method used for the accountancy analysis at nuclear fuel facilities requires the standard materials called LSD (Large Size Dried) spike. Generally, LSD spikes are prepared from certified reference materials (CRMs) which supplied from foreign laboratories. However, the difficulty of Pu CRM importation is increasing. It is important for safeguards to attain and continue high reliable accountancy analysis and stable securing of LSD spike is essential. Therefore, in order to conserve CRMs, several types of LSD spike were prepared under collaboration work between JAEA and JNFL, such as the amount of nuclear material in one LSD spike is decreased and others. Practical test with actual samples were performed at JNFL Rokkasho reprocessing plant, and those results were compared with the results obtained by using LSD spike which supplied from foreign laboratory. Preparation and verification analysis of LSD spikes and evaluation of uncertainty based on ISO-GUM will be presented. (author)

  8. G-MAPSEQ – a new method for mapping reads to a reference genome

    Directory of Open Access Journals (Sweden)

    Wojciechowski Pawel

    2016-06-01

    Full Text Available The problem of reads mapping to a reference genome is one of the most essential problems in modern computational biology. The most popular algorithms used to solve this problem are based on the Burrows-Wheeler transform and the FM-index. However, this causes some issues with highly mutated sequences due to a limited number of mutations allowed. G-MAPSEQ is a novel, hybrid algorithm combining two interesting methods: alignment-free sequence comparison and an ultra fast sequence alignment. The former is a fast heuristic algorithm which uses k-mer characteristics of nucleotide sequences to find potential mapping places. The latter is a very fast GPU implementation of sequence alignment used to verify the correctness of these mapping positions. The source code of G-MAPSEQ along with other bioinformatic software is available at: http://gpualign.cs.put.poznan.pl.

  9. ANSI/ASHRAE/IES Standard 90.1-2016 Performance Rating Method Reference Manual

    Energy Technology Data Exchange (ETDEWEB)

    Goel, Supriya [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Rosenberg, Michael I. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Eley, Charles [Eley and Associates, Hobe Sound, FL (United States)

    2017-09-29

    This document is intended to be a reference manual for the Appendix G Performance Rating Method (PRM) of ANSI/ASHRAE/IES Standard 90.1-2016 (Standard 90.1-2016). The PRM can be used to demonstrate compliance with the standard and to rate the energy efficiency of commercial and high-rise residential buildings with designs that exceed the requirements of Standard 90.1. Use of the PRM for demonstrating compliance with Standard 90.1 is a new feature of the 2016 edition. The procedures and processes described in this manual are designed to provide consistency and accuracy by filling in gaps and providing additional details needed by users of the PRM.

  10. Description of odd-mass nuclei by multi-reference energy density functional methods

    International Nuclear Information System (INIS)

    Bally, B.

    2014-01-01

    In this work, we are interested in the treatment of odd-mass atomic nuclei in energy density functional (EDF) models. More precisely, the goal of this thesis is to develop and to apply to odd-mass nuclei, the theoretical extensions of the EDF method that are: first, the projection technique, and secondly the configuration mixing by the generator coordinate method (GCM). These two extensions are part of the so-called multi-reference energy density functional (MR-EDF) formalism and allow one to take into account, within an EDF context, the 'beyond-mean-field' correlations between the nucleons forming the nucleus. Until now, the MR-EDF formalism has been applied, in its fully-fledged version, only to the calculation of even-even nuclei. In this thesis, we want to demonstrate the applicability of such a model also for the description of odd-mass nuclei. In the first part of this thesis, we describe the theoretical formalism of the EDF models, giving particular attention to the treatment of symmetries within our approach. In the second part of the manuscript, we apply our model to the nucleus 25 Mg and investigate different aspects of the method (e.g. numerical accuracy, convergence of the configuration mixing, comparison to known experimental data). The results obtained in this work are encouraging and demonstrate the potential of our approach for theoretical nuclear structure calculations. (author)

  11. Formulation of probabilistic models of protein structure in atomic detail using the reference ratio method.

    Science.gov (United States)

    Valentin, Jan B; Andreetta, Christian; Boomsma, Wouter; Bottaro, Sandro; Ferkinghoff-Borg, Jesper; Frellsen, Jes; Mardia, Kanti V; Tian, Pengfei; Hamelryck, Thomas

    2014-02-01

    We propose a method to formulate probabilistic models of protein structure in atomic detail, for a given amino acid sequence, based on Bayesian principles, while retaining a close link to physics. We start from two previously developed probabilistic models of protein structure on a local length scale, which concern the dihedral angles in main chain and side chains, respectively. Conceptually, this constitutes a probabilistic and continuous alternative to the use of discrete fragment and rotamer libraries. The local model is combined with a nonlocal model that involves a small number of energy terms according to a physical force field, and some information on the overall secondary structure content. In this initial study we focus on the formulation of the joint model and the evaluation of the use of an energy vector as a descriptor of a protein's nonlocal structure; hence, we derive the parameters of the nonlocal model from the native structure without loss of generality. The local and nonlocal models are combined using the reference ratio method, which is a well-justified probabilistic construction. For evaluation, we use the resulting joint models to predict the structure of four proteins. The results indicate that the proposed method and the probabilistic models show considerable promise for probabilistic protein structure prediction and related applications. Copyright © 2013 Wiley Periodicals, Inc.

  12. A Practical Method for Implementing an Attitude and Heading Reference System

    Directory of Open Access Journals (Sweden)

    Rodrigo Munguía

    2014-04-01

    Full Text Available This paper describes a practical and reliable algorithm for implementing an Attitude and Heading Reference System (AHRS. This kind of system is essential for real time vehicle navigation, guidance and control applications. When low cost sensors are used, efficient and robust algorithms are required for performance to be acceptable. The proposed method is based on an Extended Kalman Filter (EKF in a direct configuration. In this case, the filter is explicitly derived from both the kinematic and error models. The selection of this kind of EKF configuration can help in ensuring a tight integration of the method for its use in filter-based localization and mapping systems in autonomous vehicles. Experiments with real data show that the proposed method is able to maintain an accurate and drift-free attitude and heading estimation. An additional result is to show that there is no ostensible reason for preferring that the filter have an indirect configuration over a direct configuration for implementing an AHRS system.

  13. Development of a quality assured calibration method for the PSI radon chamber reference atmosphere

    International Nuclear Information System (INIS)

    Schuler, C.; Butterweck-Dempewolf, G.; Vezzu, G.

    1997-01-01

    Radon detectors and measuring instruments are calibrated at the PSI Reference Laboratory for Radon Gas Concentration Measurements by exposing them to a calibrated radon reference atmosphere in the PSI radon chamber. A sophisticated and quality assured calibration technique was developed which guarantees the traceability of this radon chamber reference atmosphere to standards of internationally acknowledged primary laboratories. (author) 2 figs., 2 refs

  14. Discussion Graphs

    DEFF Research Database (Denmark)

    Kiciman, Emre; Counts, Scott; Gamon, Michael

    2014-01-01

    , time and other confounding factors, few of the studies that attempt to extract information from social media actually condition on such factors due to the difficulty in extracting these factors from naturalistic data and the added complexity of including them in analyses. In this paper, we present......Much research has focused on studying complex phenomena through their reflection in social media, from drawing neighborhood boundaries to inferring relationships between medicines and diseases. While it is generally recognized in the social sciences that such studies should be conditioned on gender...... a simple framework for specifying and implementing common social media analyses that makes it trivial to inspect and condition on contextual information. Our data model—discussion graphs—captures both the structural features of relationships inferred from social media as well as the context...

  15. Solubilization methods and reference 2-DE map of cow milk fat globules.

    Science.gov (United States)

    Bianchi, Laura; Puglia, Michele; Landi, Claudia; Matteoni, Silvia; Perini, Daniele; Armini, Alessandro; Verani, Margherita; Trombetta, Claudia; Soldani, Patrizia; Roncada, Paola; Greppi, Gianfranco; Pallini, Vitaliano; Bini, Luca

    2009-07-21

    Milk fat globules (MFGs) are secretory vesicles assembled and secreted by mammary epithelial cells during lactation. They consist of fat globules surrounded by a lipid bilayer membrane which is derived from the apical membrane of the lactating cells. MFGs contain, besides lipids, proteins from the apical plasma membrane and from the cytoplasmatic material. Their peculiar vesicle nature makes them a suitable and easily available source of biological material in monitoring the physiopathological state of the mammary gland. Unfortunately, the conspicuous lipidic component of MFGs consistently limits protein extraction and purification for MFG proteomic investigations. This work deals with the development of a suitable procedure for protein extraction from the cow MFGs in order to qualitatively and quantitatively improve 2-D electropherograms of the MFG. MFGs were purified from raw milk by centrifugation and then delipidated/precipitated. The resulting protein pellets were solubilised using four different 2-D SDS PAGE compatible lysis buffers. Applied methodological procedures for protein extraction and evaluation of the resulting 2-D protein-pattern are presented and discussed. Using these procedures a reference 2-D map of cow milk fat globules is also reported. The majority of the obtained identifications was represented by proteins involved in lipid synthesis or in fat globule secretion.

  16. World Health Organization 2006 Child Growth Standards and 2007 Growth Reference Charts: A Discussion Paper by the Committee on Nutrition of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition

    DEFF Research Database (Denmark)

    Turck, Dominique; Michaelsen, Kim F.; Shamir, Raanan

    2013-01-01

    Growth charts are essential for evaluating children’s health including their nutrition; however, the evaluation of child growth trajectories and consequently the decision to intervene are highly dependent on the growth charts used. The aim of this discussion paper of the European Society for Paed......Growth charts are essential for evaluating children’s health including their nutrition; however, the evaluation of child growth trajectories and consequently the decision to intervene are highly dependent on the growth charts used. The aim of this discussion paper of the European Society...... for Paediatric Gastroenterology, Hepatology, and Nutrition Committee on Nutrition is to provide information on the background and rationale of the World Health Organization (WHO) 2006 child growth standards and WHO 2007 growth reference charts, describe their development, outline their main innovative aspects...... between different countries and ethnic groups. WHO 2007 growth reference charts (5–19 years) are based mainly on a re-analysis of National Centre for Health Statistics data from 1977, without information on feeding. European Society for Paediatric Gastroenterology, Hepatology, and Nutrition Committee...

  17. Recent advances in ratio primary reference measurement procedures (definitive methods) and their use in certification of reference materials and controlling assigned values in proficiency testing

    International Nuclear Information System (INIS)

    Dybczyñski, R.S.; Polkowska-Motrenko, H.; Chajduk, E.; Danko, B.; Pyszynska, M.

    2014-01-01

    The idea of definitive methods based on radiochemical neutron activation analysis (RNAA), consists in combination of neutron activation with the highly selective and quantitative post-irradiation isolation of the desired radionuclide by column chromatography followed by γ-ray spectrometric measurement. The principles of construction of such methods, which were devised in the Institute of Nuclear Chemistry and Technology, are reminded and the significance of these methods for analytical quality assurance is emphasized. According to VIM 3 nomenclature these methods may be called: ratio primary reference measurement procedures (RPRMPs). RPRMP for the determination of Se is briefly presented and its use for checking the accuracy of 'assigned values' established by expert laboratories in some proficiency tests, is demonstrated

  18. World Health Organization 2006 child growth standards and 2007 growth reference charts: A discussion paper by the committee on Nutrition of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition.

    Science.gov (United States)

    Turck, Dominique; Michaelsen, Kim F; Shamir, Raanan; Braegger, Christian; Campoy, Cristina; Colomb, Virginie; Decsi, Tamás; Domellöf, Magnus; Fewtrell, Mary; Kolacek, Sanja; Mihatsch, Walter; Moreno, Luis A; van Goudoever, Johannes

    2013-08-01

    Growth charts are essential for evaluating children's health including their nutrition; however, the evaluation of child growth trajectories and consequently the decision to intervene are highly dependent on the growth charts used. The aim of this discussion paper of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition Committee on Nutrition is to provide information on the background and rationale of the World Health Organization (WHO) 2006 child growth standards and WHO 2007 growth reference charts, describe their development, outline their main innovative aspects, discuss potential limitations, and make recommendations. WHO 2006 child growth standards (0-5 years) are based on prospectively collected data describing the growth of healthy infants who were breast-fed according to WHO recommendations, showing a pattern of linear growth, which is remarkably consistent between different countries and ethnic groups. WHO 2007 growth reference charts (5-19 years) are based mainly on a re-analysis of National Centre for Health Statistics data from 1977, without information on feeding. European Society for Paediatric Gastroenterology, Hepatology, and Nutrition Committee on Nutrition recommends that WHO child growth standards should be used to monitor growth in all children in the age range 0 to 2 years in Europe, whether breast- or formula-fed, and that they should be considered to be used in the age range 2 to 5 years. Implementation of the WHO child growth standards should be preceded by evaluation of the implication of their use on national healthcare policies. Health professionals should be guided on their use and interpretation and an adequate communication strategy should be available locally to ensure that parents receive clear and consistent advice. The decision on whether to implement the WHO growth references (5-19 years) should be made by national bodies because the growth pattern during the 5- to 19-year period differs between

  19. Assessing Crowdsourced POI Quality: Combining Methods Based on Reference Data, History, and Spatial Relations

    Directory of Open Access Journals (Sweden)

    Guillaume Touya

    2017-03-01

    Full Text Available With the development of location-aware devices and the success and high use of Web 2.0 techniques, citizens are able to act as sensors by contributing geographic information. In this context, data quality is an important aspect that should be taken into account when using this source of data for different purposes. The goal of the paper is to analyze the quality of crowdsourced data and to study its evolution over time. We propose two types of approaches: (1 use the intrinsic characteristics of the crowdsourced datasets; or (2 evaluate crowdsourced Points of Interest (POIs using external datasets (i.e., authoritative reference or other crowdsourced datasets, and two different methods for each approach. The potential of the combination of these approaches is then demonstrated, to overcome the limitations associated with each individual method. In this paper, we focus on POIs and places coming from the very successful crowdsourcing project: OpenStreetMap. The results show that the proposed approaches are complementary in assessing data quality. The positive results obtained for data matching show that the analysis of data quality through automatic data matching is possible but considerable effort and attention are needed for schema matching given the heterogeneity of OSM and the representation of authoritative datasets. For the features studied, it can be noted that change over time is sometimes due to disagreements between contributors, but in most cases the change improves the quality of the data.

  20. A Novel Real-Time Reference Key Frame Scan Matching Method

    Directory of Open Access Journals (Sweden)

    Haytham Mohamed

    2017-05-01

    Full Text Available Unmanned aerial vehicles represent an effective technology for indoor search and rescue operations. Typically, most indoor missions’ environments would be unknown, unstructured, and/or dynamic. Navigation of UAVs in such environments is addressed by simultaneous localization and mapping approach using either local or global approaches. Both approaches suffer from accumulated errors and high processing time due to the iterative nature of the scan matching method. Moreover, point-to-point scan matching is prone to outlier association processes. This paper proposes a low-cost novel method for 2D real-time scan matching based on a reference key frame (RKF. RKF is a hybrid scan matching technique comprised of feature-to-feature and point-to-point approaches. This algorithm aims at mitigating errors accumulation using the key frame technique, which is inspired from video streaming broadcast process. The algorithm depends on the iterative closest point algorithm during the lack of linear features which is typically exhibited in unstructured environments. The algorithm switches back to the RKF once linear features are detected. To validate and evaluate the algorithm, the mapping performance and time consumption are compared with various algorithms in static and dynamic environments. The performance of the algorithm exhibits promising navigational, mapping results and very short computational time, that indicates the potential use of the new algorithm with real-time systems.

  1. Development of a new certified reference material of diosgenin using mass balance approach and Coulometric titration method.

    Science.gov (United States)

    Gong, Ningbo; Zhang, Baoxi; Hu, Fan; Du, Hui; Du, Guanhua; Gao, Zhaolin; Lu, Yang

    2014-12-01

    Certified reference materials (CRMs) can be used as a valuable tool to validate the trueness of measurement methods and to establish metrological traceability of analytical results. Diosgenin has been selected as a candidate reference material. Characterization of the material relied on two different methods, mass balance method and Coulometric titration method (CT). The certified value of diosgenin CRM is 99.80% with an expanded uncertainty of 0.37% (k=2). The new CRM of diosgenin can be used to validate analytical methods, improve the accuracy of measurement data and control the quality of diosgenin in relevant pharmaceutical formulations. Copyright © 2014 Elsevier Inc. All rights reserved.

  2. The effects of user factors and symbol referents on public symbol design using the stereotype production method.

    Science.gov (United States)

    Ng, Annie W Y; Siu, Kin Wai Michael; Chan, Chetwyn C H

    2012-01-01

    This study investigated the influence of user factors and symbol referents on public symbol design among older people, using the stereotype production method for collecting user ideas during the symbol design process. Thirty-one older adults were asked to draw images based on 28 public symbol referents and to indicate their familiarity with and ease with which they visualised each referent. Differences were found between the pictorial solutions generated by males and females. However, symbol design was not influenced by participants' education level, vividness of visual imagery, object imagery preference or spatial imagery preference. Both familiar and unfamiliar referents were illustrated pictorially without much difficulty by users. The more visual the referent, the less difficulty the users had in illustrating it. The findings of this study should aid the optimisation of the stereotype production method for user-involved symbol design. Copyright © 2011 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  3. Validation of a liquid chromatographic method for determination of related substances in a candidate certified reference material of captopril

    Directory of Open Access Journals (Sweden)

    Raquel Nogueira

    2011-06-01

    Full Text Available This paper describes the validation of a reversed-phase high performance liquid chromatography method (RP-HPLC with diode array detection (DAD for determination of related substances (impurities from organic synthesis and degradation products of captopril according to the Brazilian Pharmacopeia IV. The aim of this study was to guarantee the method accuracy for quantification of related substances, an essential requisite to determine, using the mass balance approach, the captopril content in the first Brazilian certified reference material (CRM of an active pharmaceutical ingredient (API, developed by Inmetro. The captopril instability in solution is discussed and the captopril content determined by mass balance is compared to the results from titration and differential scanning calorimetry (DSC.Este artigo descreve a validação de método de cromatografia líquida de alta eficiência em fase reversa (CLAE-RP com detector de fotodiodos (DAD para determinação de substâncias relacionadas (impurezas orgânicas de síntese e produtos de degradação de captopril segundo Farmacopéia Brasileira IV ed. Este estudo teve como objetivo garantir que o método é capaz de quantificar com exatidão o teor de substâncias relacionadas, um requisito essencial para que o teor de captopril seja determinado por balanço de massa no primeiro material de referência certificado (MRC de fármacos brasileiro, o qual foi desenvolvido pelo Inmetro. A instabilidade do captopril em solução é discutida em detalhes e o teor de captopril determinado por balanço de massa é comparado com aqueles obtidos por titulação e por calorimetria exploratória diferencial (DSC.

  4. Medical reference dosimetry using EPR measurements of alanine: Development of an improved method for clinical dose levels

    International Nuclear Information System (INIS)

    Helt-Hansen, Jakob; Andersen, Claus Erik; Rosendal, Flemming; Kofoed, Inger Matilde

    2009-01-01

    Electron spin resonance (EPR) is used to determine the absorbed dose of alanine dosimeters exposed to clinical photon beams in a solid-water phantom. Alanine is potentially suitable for medical reference dosimetry, because of its near water equivalence over a wide energy spectrum, low signal fading, non-destructive measurement and small dosimeter size. Material and Methods. A Bruker EMX-micro EPR spectrometer with a rectangular cavity and a measurement time of two minutes per dosimeter was used for reading of irradiated alanine dosimeters. Under these conditions a new algorithm based on scaling of known spectra was developed to extract the alanine signal. Results. The dose accuracy, including calibration uncertainty, is less than 2% (k=1) above 4 Gy (n=4). The measurement uncertainty is fairly constant in absolute terms (∼30 mGy) and the relative uncertainty therefore rises for dose measurements below 4 Gy. Typical reproducibility is <1% (k=1) above 10 Gy and <2% between 4 and 10 Gy. Below 4 Gy the uncertainty is higher. A depth dose curve measurement was performed in a solid-water phantom irradiated to a dose of 20 Gy at the maximum dose point (dmax) in 6 and 18 MV photon beams. The typical difference between the dose measured with alanine in solid water and the dose measured with an ion chamber in a water tank was about 1%. A difference of 2% between 6 and 18 MV was found, possibly due to non-water equivalence of the applied phantom. Discussion. Compared to previously published methods the proposed algorithm can be applied without normalisation of phase shifts caused by changes in the g-value of the cavity. The study shows that alanine dosimetry is a suitable candidate for medical reference dosimetry especially for quality control applications

  5. MycoKey round table discussions of future directions in research on chemical detection methods, genetics and biodiversity of mycotoxins

    Science.gov (United States)

    MycoKey, an EU-funded Horizon 2020 project, includes a series of “Roundtable Discussions” to gather information on trending research areas in the field of mycotoxicology. This presentation includes summaries of the Roundtable Discussions on the role of Genetics and Biodiversity in mycotoxin product...

  6. Efficient implementation of three-dimensional reference interaction site model self-consistent-field method: application to solvatochromic shift calculations.

    Science.gov (United States)

    Minezawa, Noriyuki; Kato, Shigeki

    2007-02-07

    The authors present an implementation of the three-dimensional reference interaction site model self-consistent-field (3D-RISM-SCF) method. First, they introduce a robust and efficient algorithm for solving the 3D-RISM equation. The algorithm is a hybrid of the Newton-Raphson and Picard methods. The Jacobian matrix is analytically expressed in a computationally useful form. Second, they discuss the solute-solvent electrostatic interaction. For the solute to solvent route, the electrostatic potential (ESP) map on a 3D grid is constructed directly from the electron density. The charge fitting procedure is not required to determine the ESP. For the solvent to solute route, the ESP acting on the solute molecule is derived from the solvent charge distribution obtained by solving the 3D-RISM equation. Matrix elements of the solute-solvent interaction are evaluated by the direct numerical integration. A remarkable reduction in the computational time is observed in both routes. Finally, the authors implement the first derivatives of the free energy with respect to the solute nuclear coordinates. They apply the present method to "solute" water and formaldehyde in aqueous solvent using the simple point charge model, and the results are compared with those from other methods: the six-dimensional molecular Ornstein-Zernike SCF, the one-dimensional site-site RISM-SCF, and the polarizable continuum model. The authors also calculate the solvatochromic shifts of acetone, benzonitrile, and nitrobenzene using the present method and compare them with the experimental and other theoretical results.

  7. Experimental validation of the buildings energy performance (PEC assessment methods with reference to occupied spaces heating

    Directory of Open Access Journals (Sweden)

    Cristian PETCU

    2010-01-01

    provided by measurements and to those provided by the monthly calculation (NP 048-2006. The deviations of 1.45% and 2.2% respectively validate the hourly calculation model, as they actually have no physical significance. The report presents a phenomenological analysis of the building transfer functions synthesized as tev (τ, functions which attest their phenomenological objectivity in macro and hourly terms. The case studies completing the calculation models experimental validation emphasize unacceptably large differences between the results provided by the use of standardized calculation methods (Mc 001 / 2-2006 and SR EN 13790:2009 and those specific to the methods referred to in this report, experimentally validated.

  8. A quantitative analysis of Tl-201 myocardial perfusion image with special reference to circumferential profile method

    International Nuclear Information System (INIS)

    Miyanaga, Hajime

    1982-01-01

    A quantitative analysis of thallium-201 myocardial perfusion image (MPI) was attempted by using circumferential profile method (CPM) and the first purpose of this study is to assess the clinical utility of this method for the detection of myocardial ischemia. In patients with coronary artery disease, CPM analysis to exercise T1-MPI showed high sensitivity (9/12, 75%) and specificity (9/9, 100%), whereas exercise ECG showed high sensitivity (9/12, 75%), but relatively low specificity (7/9, 78%). In patients with myocardial infarction, CPM also showed high sensitivity (34/38, 89%) for the detection of myocardial necrosis, compared with visual interpretation (31/38, 81%) and with ECG (31/38, 81%). Defect score was correlated well with the number of abnormal Q waves. In exercise study, CPM was also sensitive to the change of perfusion defect in T1-MPI produced by exercise. So the results indicate that CPM is a good method not only quantitatively but also objectively to analyze T1-MPI. Although ECG is the most commonly used diagnostic tool for ischemic heart disease, several exercise induced ischemic changes in ECG have been still on discussion as criteria. So the second purpose of this study is to evaluate these ischemic ECG changes by exercise T1-MPI analized quantitatively. ST depression (ischemic 1 mm and junctional 2 mm or more), ST elevation (1 mm or more), and coronary T wave reversion in exercise ECG were though to be ischemic changes. (J.P.N.)

  9. Quantitative analysis of Tl-201 myocardial perfusion image with special reference to circumferential profile method

    Energy Technology Data Exchange (ETDEWEB)

    Miyanaga, Hajime [Kyoto Prefectural Univ. of Medicine (Japan)

    1982-08-01

    A quantitative analysis of thallium-201 myocardial perfusion image (MPI) was attempted by using circumferential profile method (CPM) and the first purpose of this study is to assess the clinical utility of this method for the detection of myocardial ischemia. In patients with coronary artery disease, CPM analysis to exercise T1-MPI showed high sensitivity (9/12, 75%) and specificity (9/9, 100%), whereas exercise ECG showed high sensitivity (9/12, 75%), but relatively low specificity (7/9, 78%). In patients with myocardial infarction, CPM also showed high sensitivity (34/38, 89%) for the detection of myocardial necrosis, compared with visual interpretation (31/38, 81%) and with ECG (31/38, 81%). Defect score was correlated well with the number of abnormal Q waves. In exercise study, CPM was also sensitive to the change of perfusion defect in T1-MPI produced by exercise. So the results indicate that CPM is a good method not only quantitatively but also objectively to analyze T1-MPI. Although ECG is the most commonly used diagnostic tool for ischemic heart disease, several exercise induced ischemic changes in ECG have been still on discussion as criteria. So the second purpose of this study is to evaluate these ischemic ECG changes by exercise T1-MPI analized quantitatively. ST depression (ischemic 1 mm and junctional 2 mm or more), ST elevation (1 mm or more), and coronary T wave reversion in exercise ECG were though to be ischemic changes.

  10. Pregnancy and variations of carbohydrate-deficient transferrin levels measured by the candidate reference HPLC method.

    Science.gov (United States)

    Bianchi, Vincenza; Ivaldi, Alessandra; Raspagni, Alessia; Arfini, Carlo; Vidali, Matteo

    2011-01-01

    Contrasting data are available on the diagnostic accuracy of carbohydrate-deficient transferrin (CDT) during pregnancy. These differences may depend in part on how CDT was evaluated and expressed. Here, we report on variations of CDT levels in pregnant women using the high performance liquid chromatography (HPLC) candidate reference method. Alanine aminotransferase, aspartate aminotransferase, gamma-glutamyltransferase, mean corpuscular volume, serum transferrin, urine and serum ethyl glucuronide and CDT were measured in 64 women, self-reporting as non-alcohol abusers (age: median 34, IQR: 28-38), at different stages of normal pregnancy (gestational weeks: median 28, IQR: 8-33). CDT was expressed as percentage of disialotransferrin to total transferrin (%CDT). Transferrin was associated with both %CDT (r = 0.66; P pregnancy trimester (first trimester: mean 1.01% (SD 0.19); second trimester: 1.30% (SD 0.14); third trimester: 1.53% (SD 0.22); ANOVA P pregnancy trimesters (P pregnancy and CDT could be more complex. The diagnostic accuracy of CDT for detecting alcohol abuse in a legal context may be limited in pregnant women and the effect of gestational age should be considered.

  11. Trace elements determination in silicon and ferrosilicon reference materials by instrumental neutron activation analysis method

    International Nuclear Information System (INIS)

    Moreira, Edson Goncalves; Vasconcellos, Marina Beatriz Agostini; Saiki, Mitiko; Iamashita, Celia Omine

    2002-01-01

    The use of certified reference materials, CRM, is of uppermost importance in the rastreability realization of the measurement process. At times, CRM use is restricted by the non existence of a suitable CRM with similarity to the sample in respect to matrix composition or with element levels in different orders of magnitude. IPT Chemical Division launched a project to prepare a metallic silicon CRM, due to the requirements of the industries in this field. To characterize this new CRM, IPEN Nuclear Reactor Center is able to perform instrumental neutron activation analysis, INAA, a very suitable method for silicon matrix samples because they produce basically the short lived radionuclide 3 1 Si under thermal neutrons flux, which after radioactive decay, does not interfere in the determination of other elements. In this paper, it is presented the determination of As, Br, Co, Cr, K, Eu, Fe, La, Mn, Na Nb, Sb, Sm, Sc, Th, Tb, U, V, W and Yb in silicon CRM NBS SRM 57; ferrosilicon CRM IPT 56; IPT 70; NBS SRM 58a; NBS SRM 59a and silicon RM under preparation IPT 132. From the results, the accuracy and the precision of the process were assessed. (author)

  12. Standard test method for determination of reference temperature, to, for ferritic steels in the transition range

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2011-01-01

    1.1 This test method covers the determination of a reference temperature, To, which characterizes the fracture toughness of ferritic steels that experience onset of cleavage cracking at elastic, or elastic-plastic KJc instabilities, or both. The specific types of ferritic steels (3.2.1) covered are those with yield strengths ranging from 275 to 825 MPa (40 to 120 ksi) and weld metals, after stress-relief annealing, that have 10 % or less strength mismatch relative to that of the base metal. 1.2 The specimens covered are fatigue precracked single-edge notched bend bars, SE(B), and standard or disk-shaped compact tension specimens, C(T) or DC(T). A range of specimen sizes with proportional dimensions is recommended. The dimension on which the proportionality is based is specimen thickness. 1.3 Median KJc values tend to vary with the specimen type at a given test temperature, presumably due to constraint differences among the allowable test specimens in 1.2. The degree of KJc variability among specimen types i...

  13. Evaluation of reference evapotranspiration methods for the northeastern region of India

    Directory of Open Access Journals (Sweden)

    Pankaj K. Pandey

    2016-03-01

    Full Text Available The study planed to identify a suitable alternative to the FAO-56 Penman-Monteith (FAO56PM equation for calculating reference evapotranspiration (ET0 from chosen temperature and radiation based models utilizing monthly meteorological data from 30 destinations in diverse agro-ecological regions of the Northeast (NE India i.e., Assam Bengal Plain (ABP, eastern Himalaya (EH, and the northeastern hilly (NEH region. Radiation-based IRMAK3 most appropriate in the ABP (weighted root mean square deviation, WRMSD=0.17 mm d−1, r2=0.98, for Nagrakata, and TURC model being in the first three rank of most of the sites, with the lowest error and highest correlation in NEH (WRMSD=0.10 mm d−1, r2=0.92, for Shillong, and EH (WRMSD=0.23 mm d−1, r2=0.95, for Gangtok. Findings reveal that IRMAK3 and TURC models performed equally well and were observed to be the best among selected models for the majority of stations followed by FAO24 Blaney-Criddle (FAO24BC, and 1957MAKK. Pair-wise regression equations were developed for preferred FAO56PM ET0 estimates to ET0 estimates by alternative methods. Cross-correlation of eighteen chose methods demonstrated that the five equations (i.e. four radiation- and one temperature-based performed exceptionally well when contrasted with the FAO56PM model, thus being advised for assessing ET0 under limiting data conditions as have yielded a better estimate of ET0 with a small error.

  14. The Kjeldahl method as a primary reference procedure for total protein in certified reference materials used in clinical chemistry. I. A review of Kjeldahl methods adopted by laboratory medicine.

    Science.gov (United States)

    Chromý, Vratislav; Vinklárková, Bára; Šprongl, Luděk; Bittová, Miroslava

    2015-01-01

    We found previously that albumin-calibrated total protein in certified reference materials causes unacceptable positive bias in analysis of human sera. The simplest way to cure this defect is the use of human-based serum/plasma standards calibrated by the Kjeldahl method. Such standards, commutative with serum samples, will compensate for bias caused by lipids and bilirubin in most human sera. To find a suitable primary reference procedure for total protein in reference materials, we reviewed Kjeldahl methods adopted by laboratory medicine. We found two methods recommended for total protein in human samples: an indirect analysis based on total Kjeldahl nitrogen corrected for its nonprotein nitrogen and a direct analysis made on isolated protein precipitates. The methods found will be assessed in a subsequent article.

  15. Discussion on the method to increase the successful rate of L5/S1 intervertebral disc puncture

    International Nuclear Information System (INIS)

    Zhong Xianyi; Li Liangjun; Yu Chengxin

    2007-01-01

    Objective: To study the effective methods of L 5 /S 1 intervertebral disc puncture without drilling to solve the barriers from iliaca. Methods: (1) puncturing with belly-buttock sticking out: to enlarge waist sacro-iliaca angle to move the puncture point up; (2) puncturing through intervertebral edge: puncturing through L 5 to 1/3 intervertebral disc to make the puncture point move Up; (3) puncturing through L 5 /S 1 intervertebral disc with the self-made puncture location instrument. Results with the methods, 280 cases with L 5 /S 1 intervertebral disc protrusion have been successfully punctured, with successful rate 100%. Conclusion: These methods are ideal and easy to use to treat L 5 /S 1 intervertebral disc protrusion puncture, and worth popularizing. (authors)

  16. A preliminary discussion of angiographic anatomy and variations of rabbit hepatic vessels and catheterization methods of hepatic artery

    International Nuclear Information System (INIS)

    Wang Diaodong; Yang Renjie; Zhang Hongzhi; Sun Hongliang

    2006-01-01

    Objective: To study the normal angiographic anatomy and variations of rabbit hepatic vessels, and explore the optimal method for hepatic artery catheterization. Methods: 30 rabbits were divided into two groups randomly. Modified surgical method and interventional method were used to catheterize hepatic artery respectively, and followed by angiography to demonstrate the normal anatomy and variations of rabbit celiac artery, hepatic artery and portal vein. Results: The route and distribution of rabbit celiac artery and hepatic artery were very different from human's. The commonly seen variation showed the differences in branching bifurcation of hepatic-gastric artery, with the incidence of 13.3%. The rates of successfully hepatic artery catheterization with surgical and interventional methods were 86.6%(13/15) and 80%(12/15) respectively (P>0.05). The surgical method will not be successful, whenever there's variation. Conclusion: The normal anatomy and variation of rabbit celiac artery and hepatic artery are quite different from human's. Both surgical and interventional catheterizations could be rather successful but possessing advantages and disadvantages of each its own. (authors)

  17. Discussion of the Improved Methods for Analyzing a Cantilever Beam Carrying a Tip-Mass under Base Excitation

    Directory of Open Access Journals (Sweden)

    Wang Hongjin

    2014-01-01

    Full Text Available Two improved analytical methods of calculations for natural frequencies and mode shapes of a uniform cantilever beam carrying a tip-mass under base excitation are presented based on forced vibration theory and the method of separation of variables, respectively. The cantilever model is simplified in detail by replacing the tip-mass with an equivalent inertial force and inertial moment acting at the free end of the cantilever based on D’Alembert’s principle. The concentrated equivalent inertial force and inertial moment are further represented as distributed loads using Dirac Delta Function. In this case, some typical natural frequencies and mode shapes of the cantilever model are calculated by the improved and unimproved analytical methods. The comparing results show that, after improvement, these two methods are in extremely good agreement with each other even the offset distance between the gravity center of the tip-mass and the attachment point is large. As further verification, the transient and steady displacement responses of the cantilever system under a sine base excitation are presented in which two improved methods are separately utilized. Finally, an experimental cantilever system is fabricated and the theoretical displacement responses are validated by the experimental measurements successfully.

  18. Group discussions with the health care team--a method of improving care of hypertension in general practice.

    Science.gov (United States)

    Adorian, D; Silverberg, D S; Tomer, D; Wamosher, Z

    1990-06-01

    A management-by-objective approach was used by the health care administration of the Kupat Holim Sick Fund to improve care of hypertension in 20 family practices in the city of Ashdod in central Israel. The doctor-nurse teams in these clinics met jointly on a regular basis with a physician-instructor, reviewed the results of their care of hypertension and discussed ways of improving it. Over a seven-year period, until 1988, the percentage of the population treated increased from 4.0% to 9.2% and percentage of treated patients who had diastolic pressure of 100 mmHg or more fell from 29.6% to 13.4%. Dropout rate ranged from 2.3% to 3.1% per year over the whole period. In 20 other practices in the Ashdod area in 1988 used for comparison, only 5.9% of the population was treated and the per cent treated was less than Ashdod for all age groups above 30. Dropout rate was higher, averaging 9.8% per year, and the percentage of patients with diastolic pressures of 100 mmHg or more was higher (18.1%). Thus the use of regular discussions with feedback to the health care team was associated with better detection, treatment and follow-up of hypertension.

  19. Conceptual compression discussion on a multi-linear (FTA) and systematic (FRAM) method in an offshore operation's accident modeling.

    Science.gov (United States)

    Toroody, Ahmad Bahoo; Abaei, Mohammad Mahdy; Gholamnia, Reza

    2016-12-01

    Risk assessment can be classified into two broad categories: traditional and modern. This paper is aimed at contrasting the functional resonance analysis method (FRAM) as a modern approach with the fault tree analysis (FTA) as a traditional method, regarding assessing the risks of a complex system. Applied methodology by which the risk assessment is carried out, is presented in each approach. Also, FRAM network is executed with regard to nonlinear interaction of human and organizational levels to assess the safety of technological systems. The methodology is implemented for lifting structures deep offshore. The main finding of this paper is that the combined application of FTA and FRAM during risk assessment, could provide complementary perspectives and may contribute to a more comprehensive understanding of an incident. Finally, it is shown that coupling a FRAM network with a suitable quantitative method will result in a plausible outcome for a predefined accident scenario.

  20. Long-term response to genomic selection: effects of estimation method and reference population structure for different genetic architectures.

    Science.gov (United States)

    Bastiaansen, John W M; Coster, Albart; Calus, Mario P L; van Arendonk, Johan A M; Bovenhuis, Henk

    2012-01-24

    Genomic selection has become an important tool in the genetic improvement of animals and plants. The objective of this study was to investigate the impacts of breeding value estimation method, reference population structure, and trait genetic architecture, on long-term response to genomic selection without updating marker effects. Three methods were used to estimate genomic breeding values: a BLUP method with relationships estimated from genome-wide markers (GBLUP), a Bayesian method, and a partial least squares regression method (PLSR). A shallow (individuals from one generation) or deep reference population (individuals from five generations) was used with each method. The effects of the different selection approaches were compared under four different genetic architectures for the trait under selection. Selection was based on one of the three genomic breeding values, on pedigree BLUP breeding values, or performed at random. Selection continued for ten generations. Differences in long-term selection response were small. For a genetic architecture with a very small number of three to four quantitative trait loci (QTL), the Bayesian method achieved a response that was 0.05 to 0.1 genetic standard deviation higher than other methods in generation 10. For genetic architectures with approximately 30 to 300 QTL, PLSR (shallow reference) or GBLUP (deep reference) had an average advantage of 0.2 genetic standard deviation over the Bayesian method in generation 10. GBLUP resulted in 0.6% and 0.9% less inbreeding than PLSR and BM and on average a one third smaller reduction of genetic variance. Responses in early generations were greater with the shallow reference population while long-term response was not affected by reference population structure. The ranking of estimation methods was different with than without selection. Under selection, applying GBLUP led to lower inbreeding and a smaller reduction of genetic variance while a similar response to selection was

  1. A glossary for big data in population and public health: discussion and commentary on terminology and research methods.

    Science.gov (United States)

    Fuller, Daniel; Buote, Richard; Stanley, Kevin

    2017-11-01

    The volume and velocity of data are growing rapidly and big data analytics are being applied to these data in many fields. Population and public health researchers may be unfamiliar with the terminology and statistical methods used in big data. This creates a barrier to the application of big data analytics. The purpose of this glossary is to define terms used in big data and big data analytics and to contextualise these terms. We define the five Vs of big data and provide definitions and distinctions for data mining, machine learning and deep learning, among other terms. We provide key distinctions between big data and statistical analysis methods applied to big data. We contextualise the glossary by providing examples where big data analysis methods have been applied to population and public health research problems and provide brief guidance on how to learn big data analysis methods. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  2. A quasi-experimental design based on regional variations: discussion of a method for evaluating outcomes of medical practice

    DEFF Research Database (Denmark)

    Loft, A; Andersen, T F; Madsen, Mette

    1989-01-01

    A large proportion of common medical practices are subject to substantial regional variation resulting in numerous natural experiments. Opportunities are thereby provided for outcome evaluation through quasi-experimental design. If patients treated in different regions were comparable a natural...... experiment involving alternative treatments could be regarded as 'pseudo randomised', but empirical investigations are needed to verify this prerequisite. This paper discusses the role of quasi-experimental designs in assessment of medical care with evaluation of outcomes after hysterectomy in Denmark...... groups are elicited from administrative data. We conclude that it is possible to establish a quasi-experimental design based on regional variations and that the comparability of the groups included may be assessed through registry data. The importance of technology diffusion for the prospects...

  3. Normalization Methods and Selection Strategies for Reference Materials in Stable Isotope Analyes. Review

    Energy Technology Data Exchange (ETDEWEB)

    Skrzypek, G. [West Australian Biogeochemistry Centre, John de Laeter Centre of Mass Spectrometry, School of Plant Biology, University of Western Australia, Crawley (Australia); Sadler, R. [School of Agricultural and Resource Economics, University of Western Australia, Crawley (Australia); Paul, D. [Department of Civil Engineering (Geosciences), Indian Institute of Technology Kanpur, Kanpur (India); Forizs, I. [Institute for Geochemical Research, Hungarian Academy of Sciences, Budapest (Hungary)

    2013-07-15

    Stable isotope ratio mass spectrometers are highly precise, but not accurate instruments. Therefore, results have to be normalized to one of the isotope scales (e.g., VSMOW, VPDB) based on well calibrated reference materials. The selection of reference materials, numbers of replicates, {delta}-values of these reference materials and normalization technique have been identified as crucial in determining the uncertainty associated with the final results. The most common normalization techniques and reference materials have been tested using both Monte Carlo simulations and laboratory experiments to investigate aspects of error propagation during the normalization of isotope data. The range of observed differences justifies the need to employ the same sets of standards worldwide for each element and each stable isotope analytical technique. (author)

  4. A method to obtain reference images for evaluation of ultrasonic tissue characterization techniques

    DEFF Research Database (Denmark)

    Jensen, M.S.; Wilhjelm, Jens E.; Sahl, B.

    2002-01-01

    of the macroscopic photograph, due to the histological preparation process. The histological information was "mapped back" into the format of the ultrasound images the following way: On the macroscopic images, outlines were drawn manually which defined the border of the tissue. These outlines were superimposed...... of the various tissue types. Specifically, the macroscopic image revealed the borders between the different tissues, while the histological image identified the four tissue types. A set of 12 reference images based on modified macroscopic outlines was created. The overlap between the ultrasound images...... and the macroscopic images-which are the geometrical basis for the final reference images-was between 77% and 93%. A set of 12 reference images spaced 2.5 mm, identifying spatial location of four different tissue types in porcine muscle has been created. With the reference images, it is possible to quantitatively...

  5. Synthesized view comparison method for no-reference 3D image quality assessment

    Science.gov (United States)

    Luo, Fangzhou; Lin, Chaoyi; Gu, Xiaodong; Ma, Xiaojun

    2018-04-01

    We develop a no-reference image quality assessment metric to evaluate the quality of synthesized view rendered from the Multi-view Video plus Depth (MVD) format. Our metric is named Synthesized View Comparison (SVC), which is designed for real-time quality monitoring at the receiver side in a 3D-TV system. The metric utilizes the virtual views in the middle which are warped from left and right views by Depth-image-based rendering algorithm (DIBR), and compares the difference between the virtual views rendered from different cameras by Structural SIMilarity (SSIM), a popular 2D full-reference image quality assessment metric. The experimental results indicate that our no-reference quality assessment metric for the synthesized images has competitive prediction performance compared with some classic full-reference image quality assessment metrics.

  6. A NEW APPROACH FOR CULTURING LEMNA MINOR (DUCKWEED) AND STANDARDIZED METHOD FOR USING ATRAZINE AS A REFERENCE TOXICANT

    Science.gov (United States)

    Lemna minor (Duckweed) is commonly used in aquatic toxicity investigations. Methods for culturing and testing with reference toxicants, such as atrazine, are somewhat variable among researchers. Our goal was to develop standardized methods of culturing and testing for use with L....

  7. Analysis of progressive distorsion. Validation of the method based on effective primary stress. Discussion of Anderson's experimental data

    International Nuclear Information System (INIS)

    Moulin, Didier.

    1981-02-01

    An empirical rule usable for design by analysis against progressive distorsion has been set up from experiments conducted in C.E.N. Saclay. This rule is checked with experimental data obtained by W.F. ANDERSON, this experiment is sufficiently different from the Saclay one to evaluate the merits of the rule. The satisfactory results achieved, are another validation of the efficiency diagram on which the method is based [fr

  8. Discussion on the source of radon in uranium exploration method using radon-released thermal effect in minerals

    International Nuclear Information System (INIS)

    Su Shoutian.

    1985-01-01

    This paper considers the problem of the source of radon in uranium exploration method using radon-released thermal effect. In minerals by means of scintillation emanometry, we have carried out the measurement on radon content in minerals at various temperature in barren and ore-bearing granites of the granite-type uranium deposit No. 752, and inclusion decrepitation method has also been used to determine the temperature of decrepitation and its relative frequency. It was found from experiments that heated samples may release most of radon prior to inclusion decrepitation, radon released from thermal effect was, on the contrary, very little at temperature intervals of inclusion decrepitation on a large scale basis. When inclusions were ground after radon releasing, it would still release from inclusions after reheating. The radon content calculated from uranium content in inclusions is lower than the sensitivity of the determination method, so it is too difficult to be determined, indicating that the radon content released is not related to inclusions. Samples were determined by uranium chemical analysis and radium radiochemical analysis and it is obvious to note that the radon content released from thermal effect in minerals is positively correlated to the uranium and radium content. Various kinds of experiments suggest that radon is not derived from inclusions but from the whole mineral

  9. Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium

    Directory of Open Access Journals (Sweden)

    Louise C. Laurent

    2015-08-01

    Full Text Available Extracellular RNAs (exRNAs have been identified in all tested biofluids and have been associated with a variety of extracellular vesicles, ribonucleoprotein complexes and lipoprotein complexes. Much of the interest in exRNAs lies in the fact that they may serve as signalling molecules between cells, their potential to serve as biomarkers for prediction and diagnosis of disease and the possibility that exRNAs or the extracellular particles that carry them might be used for therapeutic purposes. Among the most significant bottlenecks to progress in this field is the lack of robust and standardized methods for collection and processing of biofluids, separation of different types of exRNA-containing particles and isolation and analysis of exRNAs. The Sample and Assay Standards Working Group of the Extracellular RNA Communication Consortium is a group of laboratories funded by the U.S. National Institutes of Health to develop such methods. In our first joint endeavour, we held a series of conference calls and in-person meetings to survey the methods used among our members, placed them in the context of the current literature and used our findings to identify areas in which the identification of robust methodologies would promote rapid advancements in the exRNA field.

  10. Setting reference targets

    International Nuclear Information System (INIS)

    Ruland, R.E.

    1997-04-01

    Reference Targets are used to represent virtual quantities like the magnetic axis of a magnet or the definition of a coordinate system. To explain the function of reference targets in the sequence of the alignment process, this paper will first briefly discuss the geometry of the trajectory design space and of the surveying space, then continue with an overview of a typical alignment process. This is followed by a discussion on magnet fiducialization. While the magnetic measurement methods to determine the magnetic centerline are only listed (they will be discussed in detail in a subsequent talk), emphasis is given to the optical/mechanical methods and to the task of transferring the centerline position to reference targets

  11. A method of camera calibration in the measurement process with reference mark for approaching observation space target

    Science.gov (United States)

    Zhang, Hua; Zeng, Luan

    2017-11-01

    Binocular stereoscopic vision can be used for space-based space targets near observation. In order to solve the problem that the traditional binocular vision system cannot work normally after interference, an online calibration method of binocular stereo measuring camera with self-reference is proposed. The method uses an auxiliary optical imaging device to insert the image of the standard reference object into the edge of the main optical path and image with the target on the same focal plane, which is equivalent to a standard reference in the binocular imaging optical system; When the position of the system and the imaging device parameters are disturbed, the image of the standard reference will change accordingly in the imaging plane, and the position of the standard reference object does not change. The camera's external parameters can be re-calibrated by the visual relationship of the standard reference object. The experimental results show that the maximum mean square error of the same object can be reduced from the original 72.88mm to 1.65mm when the right camera is deflected by 0.4 degrees and the left camera is high and low with 0.2° rotation. This method can realize the online calibration of binocular stereoscopic vision measurement system, which can effectively improve the anti - jamming ability of the system.

  12. The Use of Orientation/Decision/Do/Discuss/Reflect (OD3R) Method to Increase Critical Thinking Skill and Practical Skill in Biochemistry Learning

    Science.gov (United States)

    Anwar, Yunita Arian Sani; Senam, Senam; Laksono, Endang W.

    2018-01-01

    We have developed an OD3R method that can be applied on Biochemistry learning. This OD3R consists of 5 phases: orientation, decision, do, discuss, and reflect to connect lessons in the class with practice in the laboratory. Implementation of OD3R method was done in 2 universities in Yogyakarta to increase critical thinking skill and practical…

  13. Help! A simple method for getting back-up help to the reference desk

    Directory of Open Access Journals (Sweden)

    Kenneth Furuta

    2008-03-01

    Full Text Available Using the "net send" command, native to Windows XP, librarians at the University of California, Riverside created a "help button" for the reference desk. The simple script file sends a message to librarians' workstations in their offices and logs the date and time of use. This paper describes that program.

  14. Reference test methods for total water in lint cotton by Karl Fischer Titration and low temperature distillation

    Science.gov (United States)

    In a study of comparability of total water contents (%) of conditioned cottons by Karl Fischer Titration (KFT) and Low Temperature Distillation (LTD) reference methods, we demonstrated a match of averaged results based on a large number of replications and weighing the test specimens at the same tim...

  15. SPM analysis of parametric (R)-[11C]PK11195 binding images: plasma input versus reference tissue parametric methods

    NARCIS (Netherlands)

    Schuitemaker, Alie; van Berckel, Bart N. M.; Kropholler, Marc A.; Veltman, Dick J.; Scheltens, Philip; Jonker, Cees; Lammertsma, Adriaan A.; Boellaard, Ronald

    2007-01-01

    (R)-[11C]PK11195 has been used for quantifying cerebral microglial activation in vivo. In previous studies, both plasma input and reference tissue methods have been used, usually in combination with a region of interest (ROI) approach. Definition of ROIs, however, can be labourious and prone to

  16. A study on the optimization of referring method about medical images using MIH (Medical Image History)

    International Nuclear Information System (INIS)

    Kim, Sun Chil; Kim, Jung Min

    2002-01-01

    The recent development of embodiment technology of the medical images makes most medical institutions introduce PACS (Picture Archiving and Communication System) in haste. However lots of PACS solutions, currently developed and distributed, haven't been able to serve the convenience of users and to satisfy user's demand because of economic limitations and administrator-oriented con-siderations in the process of development. So we have developed MIH (Medical Image History), by which we can search and refer to the patient's medical images and information with few restrictions of time and space for diagnosis and treatment. The program will contribute to the improvement in the medical environment and meet the clients' need. We'll make more effort to develop the application which insures the better quality of medical images. MIH manages the patient's image files and medical records like film chart in connection with time. This trial will contribute to the reduction of the economical loss caused by unnecessary references and improve the quality in the medical services. The demand on the development of the program which refers to the medical data quickly and keeps them stable will be continued by the medical institute. This will satisfy the client's demand and improve the service to the patients in that the program will be modified from the standpoint of the users. MIH is trying to keep user-oriented policy and to apply the benefit of the analog system to the digital environment. It is necessary to lead the public to the better understanding that the systematic management and referring of the medical images is as important as the quality of the images

  17. A study on the optimization of referring method about medical images using MIH (Medical Image History)

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sun Chil; Kim, Jung Min [College of Health Sciences, Korea University, Seoul (Korea, Republic of)

    2002-09-15

    The recent development of embodiment technology of the medical images makes most medical institutions introduce PACS (Picture Archiving and Communication System) in haste. However lots of PACS solutions, currently developed and distributed, haven't been able to serve the convenience of users and to satisfy user's demand because of economic limitations and administrator-oriented con-siderations in the process of development. So we have developed MIH (Medical Image History), by which we can search and refer to the patient's medical images and information with few restrictions of time and space for diagnosis and treatment. The program will contribute to the improvement in the medical environment and meet the clients' need. We'll make more effort to develop the application which insures the better quality of medical images. MIH manages the patient's image files and medical records like film chart in connection with time. This trial will contribute to the reduction of the economical loss caused by unnecessary references and improve the quality in the medical services. The demand on the development of the program which refers to the medical data quickly and keeps them stable will be continued by the medical institute. This will satisfy the client's demand and improve the service to the patients in that the program will be modified from the standpoint of the users. MIH is trying to keep user-oriented policy and to apply the benefit of the analog system to the digital environment. It is necessary to lead the public to the better understanding that the systematic management and referring of the medical images is as important as the quality of the images.

  18. Efficient speed control of induction motor using RBF based model reference adaptive control method

    OpenAIRE

    Kilic, Erdal; Ozcalik, Hasan Riza; Yilmaz, Saban

    2017-01-01

    This paper proposes a model reference adaptive speed controller based on artificial neural network for induction motor drives. The performance of traditional feedback controllers has been insufficient in speed control of induction motors due to nonlinear structure of the system, changing environmental conditions, and disturbance input effects. A successful speed control of induction motor requires a nonlinear control system. On the other hand, in recent years, it has been demonstrated that ar...

  19. A novel SNP analysis method to detect copy number alterations with an unbiased reference signal directly from tumor samples

    Directory of Open Access Journals (Sweden)

    LaFramboise William A

    2011-01-01

    Full Text Available Abstract Background Genomic instability in cancer leads to abnormal genome copy number alterations (CNA as a mechanism underlying tumorigenesis. Using microarrays and other technologies, tumor CNA are detected by comparing tumor sample CN to normal reference sample CN. While advances in microarray technology have improved detection of copy number alterations, the increase in the number of measured signals, noise from array probes, variations in signal-to-noise ratio across batches and disparity across laboratories leads to significant limitations for the accurate identification of CNA regions when comparing tumor and normal samples. Methods To address these limitations, we designed a novel "Virtual Normal" algorithm (VN, which allowed for construction of an unbiased reference signal directly from test samples within an experiment using any publicly available normal reference set as a baseline thus eliminating the need for an in-lab normal reference set. Results The algorithm was tested using an optimal, paired tumor/normal data set as well as previously uncharacterized pediatric malignant gliomas for which a normal reference set was not available. Using Affymetrix 250K Sty microarrays, we demonstrated improved signal-to-noise ratio and detected significant copy number alterations using the VN algorithm that were validated by independent PCR analysis of the target CNA regions. Conclusions We developed and validated an algorithm to provide a virtual normal reference signal directly from tumor samples and minimize noise in the derivation of the raw CN signal. The algorithm reduces the variability of assays performed across different reagent and array batches, methods of sample preservation, multiple personnel, and among different laboratories. This approach may be valuable when matched normal samples are unavailable or the paired normal specimens have been subjected to variations in methods of preservation.

  20. Comparison of model reference and map based control method for vehicle stability enhancement

    NARCIS (Netherlands)

    Baek, S.; Son, M.; Song, J.; Boo, K.; Kim, H.

    2012-01-01

    A map based controller method to improve a vehicle lateral stability is proposed in this study and compared with the conventional method, a model referenced controller. A model referenced controller to determine compensated yaw moment uses the sliding mode method, but the proposed map based

  1. A simple method for measuring glucose utilization of insulin-sensitive tissues by using the brain as a reference

    International Nuclear Information System (INIS)

    Namba, Hiroki; Nakagawa, Keiichi; Iyo, Masaomi; Fukushi, Kiyoshi; Irie, Toshiaki

    1994-01-01

    A simple method, without measurement of the plasma input function, to obtain semiquantitative values of glucose utilization in tissues other than the brain with radioactive deoxyglucose is reported. The brain, in which glucose utilization is essentially insensitive to plasma glucose and insulin concentrations, was used as an internal reference. The effects of graded doses of oral glucose loading (0.5, 1 and 2 mg/g body weight) on insulin-sensitive tissues (heart, muscle and fat tissue) were studied in the rat. By using the brain-reference method, dose-dependent increases in glucose utilization were clearly shown in all the insulin-sensitive tissues examined. The method seems to be of value for measurement of glucose utilization using radioactive deoxyglucose and positron emission tomography in the heart or other insulin-sensitive tissues, especially during glucose loading. (orig.)

  2. TLC densitometric method for screening of lycopsamine in comfrey root (Symphytum officinale L. extracts using retrorsine as a reference compound

    Directory of Open Access Journals (Sweden)

    Janeš Damjan

    2014-12-01

    Full Text Available Due to severe toxicity of pyrrolizidine alkaloids, their quantification in medicinal products is very important. The idea of this research was to use retrorsine as a surrogate reference compound instead of lycopsamine reference or lycopsamine isolated from comfrey. A method for the analysis of lycopsamine in extracts of comfrey roots was developed and validated, employing thin layer chromatography, derivatisation with Dann-Mattocks reagent followed by densitometric analysis. The new method showed linearity within 0.70 to 7.0 μg of lycopsamine per application of 10 μL of a solution. It has also been proven to be specific and precise (repeatability RSD 2-4 % within the plate. The method was successfully employed for quantification of lycopsamine in comfrey root and comfrey root medicinal products such as ointments.

  3. TLC densitometric method for screening of lycopsamine in comfrey root (Symphytum officinale L.) extracts using retrorsine as a reference compound.

    Science.gov (United States)

    Janeš, Damjan; Kreft, Samo

    2014-12-01

    Due to severe toxicity of pyrrolizidine alkaloids, their quantification in medicinal products is very important. The idea of this research was to use retrorsine as a surrogate reference compound instead of lycopsamine reference or lycopsamine isolated from comfrey. A method for the analysis of lycopsamine in extracts of comfrey roots was developed and validated, employing thin layer chromatography, derivatisation with Dann-Mattocks reagent followed by densitometric analysis. The new method showed linearity within 0.70 to 7.0 μg of lycopsamine per application of 10 μL of a solution. It has also been proven to be specific and precise (repeatability RSD 2-4 % within the plate). The method was successfully employed for quantification of lycopsamine in comfrey root and comfrey root medicinal products such as ointments.

  4. Discussion on sensor location in circular array for spatial autocorrelation method; Kukan jiko sokanho no enkei array ni okeru jishinkei haichi no kento

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, H; Iwamoto, K; Saito, T; Yoshida, A [Iwate University, Iwate (Japan). Faculty of Engineering

    1997-05-27

    Methods to derive underground structures by utilizing the dispersion phenomenon of surface waves contained in microtremors include the frequency-wave number analysis method (the F-K method) and the spatial autocorrelation method (SAC method). The SAC method is said capable of estimating the structures to deeper depths than with the F-K method if the same seismometer is used. However, the F-K method is used more frequently. This is because the SAC method imposes a strict restriction that seismometers must be arranged evenly on the same circumference, while the F-K method allows seismometers to be arranged arbitrarily during an observation. Therefore, the present study has discussed whether the SAC method can be applied to observations with the seismometers arranged in the same way as in the F-K method, by using microtremor data acquired from actual observations. It was made clear that a seismometer arrangement for the SAC method may be sufficed with at least three meters arranged on the same circumference. These meters may not have to be arranged evenly, but because the acquired phase velocities may vary according to wave arriving directions and seismometer arrangement, it is desirable to perform observations with seismometers arranged as evenly as possible. 13 figs.

  5. The utility of optical detection system (qPCR) and bioinformatics methods in reference gene expression analysis

    Science.gov (United States)

    Skarzyńska, Agnieszka; Pawełkowicz, Magdalena; PlÄ der, Wojciech; Przybecki, Zbigniew

    2016-09-01

    Real-time quantitative polymerase chain reaction is consider as the most reliable method for gene expression studies. However, the expression of target gene could be misinterpreted due to improper normalization. Therefore, the crucial step for analysing of qPCR data is selection of suitable reference genes, which should be validated experimentally. In order to choice the gene with stable expression in the designed experiment, we performed reference gene expression analysis. In this study genes described in the literature and novel genes predicted as control genes, based on the in silico analysis of transcriptome data were used. Analysis with geNorm and NormFinder algorithms allow to create the ranking of candidate genes and indicate the best reference for flower morphogenesis study. According to the results, genes CACS and CYCL were characterised the most stable expression, but the least suitable genes were TUA and EF.

  6. Automatic Enhancement of the Reference Set for Multi-Criteria Sorting in The Frame of Theseus Method

    Directory of Open Access Journals (Sweden)

    Fernandez Eduardo

    2014-05-01

    Full Text Available Some recent works have established the importance of handling abundant reference information in multi-criteria sorting problems. More valid information allows a better characterization of the agent’s assignment policy, which can lead to an improved decision support. However, sometimes information for enhancing the reference set may be not available, or may be too expensive. This paper explores an automatic mode of enhancing the reference set in the framework of the THESEUS multi-criteria sorting method. Some performance measures are defined in order to test results of the enhancement. Several theoretical arguments and practical experiments are provided here, supporting a basic advantage of the automatic enhancement: a reduction of the vagueness measure that improves the THESEUS accuracy, without additional efforts from the decision agent. The experiments suggest that the errors coming from inadequate automatic assignments can be kept at a manageable level.

  7. The Kjeldahl method as a primary reference procedure for total protein in certified reference materials used in clinical chemistry. II. Selection of direct Kjeldahl analysis and its preliminary performance parameters.

    Science.gov (United States)

    Vinklárková, Bára; Chromý, Vratislav; Šprongl, Luděk; Bittová, Miroslava; Rikanová, Milena; Ohnútková, Ivana; Žaludová, Lenka

    2015-01-01

    To select a Kjeldahl procedure suitable for the determination of total protein in reference materials used in laboratory medicine, we reviewed in our previous article Kjeldahl methods adopted by clinical chemistry and found an indirect two-step analysis by total Kjeldahl nitrogen corrected for its nonprotein nitrogen and a direct analysis made on isolated protein precipitates. In this article, we compare both procedures on various reference materials. An indirect Kjeldahl method gave falsely lower results than a direct analysis. Preliminary performance parameters qualify the direct Kjeldahl analysis as a suitable primary reference procedure for the certification of total protein in reference laboratories.

  8. Encouraging Classroom Discussion

    Directory of Open Access Journals (Sweden)

    Robert Joseph McKee

    2014-10-01

    Full Text Available Classroom discussion has the potential to enhance the learning environment and encourages students to become active participants in the educational process. Student participation in classroom discussion has been shown to significantly improve the student learning experience. Research suggests that classroom discussion is an effective method for encouraging student classroom participation and for motivating student learning beyond the classroom. Participation in classroom discussion encourages students to become active collaborators in the learning process, while at the same time providing instructors with a practical method of assessing student learning. Classroom discussion is an effective tool for developing higher-level cognitive skills like critical thinking. Despite the potential discussion holds for student learning, many in academia lament the lack of participation in the classroom. The lack of student participation in classroom discussion is not a recent problem; it is one that has frustrated instructors for decades. Instructors report that some of the more current methods for encouraging classroom discussion can be exasperating and at times non-productive. This two-year study of 510 college and university students provides insight into the reasons why some students do not participate in classroom discussion. This study, which also elicited input from sixteen college and university professors and two high school teachers, offers some suggestions for creating and encouraging an environment conducive to student participation in the classroom.

  9. Standard Test Method for Determination of the Spectral Mismatch Parameter Between a Photovoltaic Device and a Photovoltaic Reference Cell

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2010-01-01

    1.1 This test method covers a procedure for the determination of a spectral mismatch parameter used in performance testing of photovoltaic devices. 1.2 The spectral mismatch parameter is a measure of the error, introduced in the testing of a photovoltaic device, caused by mismatch between the spectral responses of the photovoltaic device and the photovoltaic reference cell, as well as mismatch between the test light source and the reference spectral irradiance distribution to which the photovoltaic reference cell was calibrated. Examples of reference spectral irradiance distributions are Tables E490 or G173. 1.3 The spectral mismatch parameter can be used to correct photovoltaic performance data for spectral mismatch error. 1.4 This test method is intended for use with linear photovoltaic devices. 1.5 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard. 1.6 This standard does not purport to address all of the safety concerns, if any, a...

  10. Determination of reference data of REB diodes by using a numerical method for different applications

    International Nuclear Information System (INIS)

    Sinman, S.; Sinman, A.

    1982-01-01

    In this study, some reference data of a REB diode are presented functionally. These given characteristics are consisted of the computational results. Generally the numerical scheme depends upon the essential parameters of the charged transmission line and Child-Langmuir's diode model. By this system, further the correlation functions, some other definite functions such as the voltage of transmission line Vsub(L)(t), the diode voltage Vsub(d)(t), the diode current Isub(d)(t), the diode impedance Rsub(d)(t), the diode input power Wsub(d)(t), the dissipated energy Usub(d)(t), the efficiency phi, the beam density nsub(b)(t), the relativistic beam energy Usub(b)(t), and the intrinsic impedance Zsub(int)(t) have also been investigated. (author)

  11. 75 FR 45627 - Office of Research and Development; Ambient Air Monitoring Reference and Equivalent Methods...

    Science.gov (United States)

    2010-08-03

    ... Research and Development on March 30, 2010. The analytical procedure of this method has been tested in... Protection Agency, Research Triangle Park, North Carolina 27711. Designation of this new equivalent method is... ENVIRONMENTAL PROTECTION AGENCY [FRL-9184-5] Office of Research and Development; Ambient Air...

  12. Implementation of the multireference Brillouin-Wigner and Mukherjee’s coupled cluster methods with non-iterative triple excitations utilizing reference-level parallelism

    Energy Technology Data Exchange (ETDEWEB)

    Bhaskaran-Nair, Kiran; Brabec, Jiri; Apra, Edoardo; van Dam, Hubertus JJ; Pittner, Jiri; Kowalski, Karol

    2012-09-07

    In this paper we discuss the performance of the non-iterative State-Specific Mul- tireference Coupled Cluster (SS-MRCC) methods accounting for the effect of triply excited cluster amplitudes. The corrections to the Brillouin-Wigner and Mukherjee MRCC models based on the manifold of singly and doubly excited cluster amplitudes (BW-MRCCSD and Mk-MRCCSD, respectively) are tested and compared with the exact full configuration interaction results (FCI) for small systems (H2O, N2, and Be3). For larger systems (naphthyne isomers and -carotene), the non-iterative BW-MRCCSD(T) and Mk-MRCCSD(T) methods are compared against the results obtained with the single reference coupled cluster methods. We also report on the parallel performance of the non-iterative implementations based on the use of pro- cessor groups.

  13. Discussion in Postsecondary Classrooms

    Directory of Open Access Journals (Sweden)

    Curt Dudley-Marling

    2013-11-01

    Full Text Available Spoken language is, arguably, the primary means by which teachers teach and students learn. Much of the literature on language in classrooms has focused on discussion that is seen as both a method of instruction and a curricular outcome. While much of the research on discussion has focused on K-12 classrooms, there is also a body of research examining the efficacy of discussion in postsecondary settings. This article provides a review of this literature in order to consider the effect of discussion on student learning in college and university classrooms, the prevalence of discussion in postsecondary settings, and the quality of discussion in these settings. In general, the results of research on the efficacy of discussion in postsecondary settings are mixed. More seriously, researchers have not been explicit about the meaning of discussion and much of what is called discussion in this body of research is merely recitation with minimal levels of student participation. Although the research on discussion in college and university classrooms is inconclusive, some implications can be drawn from this review of the research including the need for future researchers to clearly define what they mean by “discussion.”

  14. Formulation of probabilistic models of protein structure in atomic detail using the reference ratio method

    DEFF Research Database (Denmark)

    Valentin, Jan B.; Andreetta, Christian; Boomsma, Wouter

    2014-01-01

    We propose a method to formulate probabilistic models of protein structure in atomic detail, for a given amino acid sequence, based on Bayesian principles, while retaining a close link to physics. We start from two previously developed probabilistic models of protein structure on a local length s....... The results indicate that the proposed method and the probabilistic models show considerable promise for probabilistic protein structure prediction and related applications. © 2013 Wiley Periodicals, Inc....

  15. Compilation of references, data sources and analysis methods for LMFBR primary piping system components

    International Nuclear Information System (INIS)

    Reich, M.; Esztergar, E.P.; Ellison, E.G.; Erdogan, F.; Gray, T.G.F.; Wells, C.W.

    1977-03-01

    A survey and review program for application of fracture mechanics methods in elevated temperature design and safety analysis has been initiated in December of 1976. This is the first of a series of reports, the aim of which is to provide a critical review of the theories of fracture and the application of fracture mechanics methods to life prediction, reliability and safety analysis of piping components in nuclear plants undergoing sub-creep and elevated temperature service conditions

  16. Reference peak method for analysis of doublets in gamma-ray spectrometry used in neutron activation analysis

    International Nuclear Information System (INIS)

    Wasek, M.; Cichowlas, A.; Sterlinski, S.; Dybczynski, R.

    2000-01-01

    A simple algebraic method for the quantitative analysis of doublets in gamma-ray spectra from HPGe detectors is presented. The calculation algorithm is accomplished using the Microsoft Excel program. The method does not require any assumptions regarding the shape of the peaks in the spectrum. The possibilities of quantitative analysis of doublets of various intensity ration and separation of ots components are discussed in detail. The practical examples proved the usefulness the method also for the analysis of the closed doublets. (author)

  17. Urbanist workshops between theory and practice: The importance of spatial and programme reference levels in the planning method

    OpenAIRE

    Gregor Čok

    2013-01-01

    One of the key characteristics of urban-architectural workshops as a soft planning method is above all the fact that the authors are free of burden of formal facts and reference levels of the local environment, which do not influence the concept and the working process. Within this framework, the workshop presents an opportunity for the creator to focus primarily on the core of the problem, and work creatively towards a substantiated professional solution. In addition to the basic ref...

  18. Kernel reconstruction methods for Doppler broadening — Temperature interpolation by linear combination of reference cross sections at optimally chosen temperatures

    International Nuclear Information System (INIS)

    Ducru, Pablo; Josey, Colin; Dibert, Karia; Sobes, Vladimir; Forget, Benoit; Smith, Kord

    2017-01-01

    This paper establishes a new family of methods to perform temperature interpolation of nuclear interactions cross sections, reaction rates, or cross sections times the energy. One of these quantities at temperature T is approximated as a linear combination of quantities at reference temperatures (T_j). The problem is formalized in a cross section independent fashion by considering the kernels of the different operators that convert cross section related quantities from a temperature T_0 to a higher temperature T — namely the Doppler broadening operation. Doppler broadening interpolation of nuclear cross sections is thus here performed by reconstructing the kernel of the operation at a given temperature T by means of linear combination of kernels at reference temperatures (T_j). The choice of the L_2 metric yields optimal linear interpolation coefficients in the form of the solutions of a linear algebraic system inversion. The optimization of the choice of reference temperatures (T_j) is then undertaken so as to best reconstruct, in the L∞ sense, the kernels over a given temperature range [T_m_i_n,T_m_a_x]. The performance of these kernel reconstruction methods is then assessed in light of previous temperature interpolation methods by testing them upon isotope "2"3"8U. Temperature-optimized free Doppler kernel reconstruction significantly outperforms all previous interpolation-based methods, achieving 0.1% relative error on temperature interpolation of "2"3"8U total cross section over the temperature range [300 K,3000 K] with only 9 reference temperatures.

  19. SPM analysis of parametric (R)-[11C]PK11195 binding images: plasma input versus reference tissue parametric methods.

    Science.gov (United States)

    Schuitemaker, Alie; van Berckel, Bart N M; Kropholler, Marc A; Veltman, Dick J; Scheltens, Philip; Jonker, Cees; Lammertsma, Adriaan A; Boellaard, Ronald

    2007-05-01

    (R)-[11C]PK11195 has been used for quantifying cerebral microglial activation in vivo. In previous studies, both plasma input and reference tissue methods have been used, usually in combination with a region of interest (ROI) approach. Definition of ROIs, however, can be labourious and prone to interobserver variation. In addition, results are only obtained for predefined areas and (unexpected) signals in undefined areas may be missed. On the other hand, standard pharmacokinetic models are too sensitive to noise to calculate (R)-[11C]PK11195 binding on a voxel-by-voxel basis. Linearised versions of both plasma input and reference tissue models have been described, and these are more suitable for parametric imaging. The purpose of this study was to compare the performance of these plasma input and reference tissue parametric methods on the outcome of statistical parametric mapping (SPM) analysis of (R)-[11C]PK11195 binding. Dynamic (R)-[11C]PK11195 PET scans with arterial blood sampling were performed in 7 younger and 11 elderly healthy subjects. Parametric images of volume of distribution (Vd) and binding potential (BP) were generated using linearised versions of plasma input (Logan) and reference tissue (Reference Parametric Mapping) models. Images were compared at the group level using SPM with a two-sample t-test per voxel, both with and without proportional scaling. Parametric BP images without scaling provided the most sensitive framework for determining differences in (R)-[11C]PK11195 binding between younger and elderly subjects. Vd images could only demonstrate differences in (R)-[11C]PK11195 binding when analysed with proportional scaling due to intersubject variation in K1/k2 (blood-brain barrier transport and non-specific binding).

  20. Evaluating the construct of triage acuity against a set of reference vignettes developed via modified Delphi method.

    Science.gov (United States)

    Twomey, Michèle; Wallis, Lee A; Myers, Jonathan E

    2014-07-01

    To evaluate the construct of triage acuity as measured by the South African Triage Scale (SATS) against a set of reference vignettes. A modified Delphi method was used to develop a set of reference vignettes. Delphi participants completed a 2-round consensus-building process, and independently assigned triage acuity ratings to 100 written vignettes unaware of the ratings given by others. Triage acuity ratings were summarised for all vignettes, and only those that reached 80% consensus during round 2 were included in the reference set. Triage ratings for the reference vignettes given by two independent experts using the SATS were compared with the ratings given by the international Delphi panel. Measures of sensitivity, specificity, associated percentages for over-triage/under-triage were used to evaluate the construct of triage acuity (as measured by the SATS) by examining the association between the ratings by the two experts and the international panel. On completion of the Delphi process, 42 of the 100 vignettes reached 80% consensus on their acuity rating and made up the reference set. On average, over all acuity levels, sensitivity was 74% (CI 64% to 82%), specificity 92% (CI 87% to 94%), under-triage occurred 14% (CI 8% to 23%) and over-triage 12% (CI 8% to 23%) of the time. The results of this study provide an alternative to evaluating triage scales against the construct of acuity as measured with the SATS. This method of using 80% consensus vignettes may, however, systematically bias the validity estimate towards better performance. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  1. Evaluation and Recalibration of Empirical Constant for Estimation of Reference Crop Evapotranspiration against the Modified Penman Method

    Science.gov (United States)

    Sasireka, K.; Jagan Mohan Reddy, C.; Charan Reddy, C.; Ramakrishnan, K.

    2017-07-01

    The major demand in our country is irrigation demand. Looking to the low irrigation potential and small water resources, it is felt necessary to see that water must be used economically and efficiently. This may be achieved by using latest methods of determination of water requirements for crops and applying the proper water management practices. Evapotranspiration (ET) is a basic for calculation of water requirement for crops. The various popular empirical equations for reference crop evapotranspiration (ETr) belong to three categories namely, Temperature, Radiation based methods and Combined methods. The above methods are site specific; hence it is necessary to recalibrate the coefficients for applying them in India. In the present paper, the standard combined method namely FAO modified Penman method was used to recalibrate the constants in temperature based (TB) methods and it can also be used to determine the ETr for the selected station. Four TB evapotranspiration models namely Blaney-Criddle, Romanenko, Kharrufa, and, Thronthwaite methods are recalibrated and the constant in each method are redefined for the data from Lekkur station, Cuddalore district in India. The result shows that, large error existed when ETr has been calculated with original constants. Hence regression equations were developed to minimise these variations in magnitude. It was found that out of four methods the Blaney-Criddle method suits better for the selected region.

  2. Comparison of methods for certification of stannic, stibium and lead traces in reference materials for steel

    Directory of Open Access Journals (Sweden)

    I. V. Khodakovskaya

    2016-01-01

    Full Text Available Development and introduction of new metallurgical technologies, new additional chemical compound indexes controlled in metallurgical materials demand to develop the new, more advanced methods of analytical control. The particular attention should be paid to identify the traces of stannic, stinium and lead because of their influence on metal characteristics.

  3. Methods And Systems For Using Reference Images In Acoustic Image Processing

    Science.gov (United States)

    Moore, Thomas L.; Barter, Robert Henry

    2005-01-04

    A method and system of examining tissue are provided in which a field, including at least a portion of the tissue and one or more registration fiducials, is insonified. Scattered acoustic information, including both transmitted and reflected waves, is received from the field. A representation of the field, including both the tissue and the registration fiducials, is then derived from the received acoustic radiation.

  4. Reference Proteome Extracts for Mass Spec Instrument Performance Validation and Method Development

    Science.gov (United States)

    Rosenblatt, Mike; Urh, Marjeta; Saveliev, Sergei

    2014-01-01

    Biological samples of high complexity are required to test protein mass spec sample preparation procedures and validate mass spec instrument performance. Total cell protein extracts provide the needed sample complexity. However, to be compatible with mass spec applications, such extracts should meet a number of design requirements: compatibility with LC/MS (free of detergents, etc.)high protein integrity (minimal level of protein degradation and non-biological PTMs)compatibility with common sample preparation methods such as proteolysis, PTM enrichment and mass-tag labelingLot-to-lot reproducibility Here we describe total protein extracts from yeast and human cells that meet the above criteria. Two extract formats have been developed: Intact protein extracts with primary use for sample preparation method development and optimizationPre-digested extracts (peptides) with primary use for instrument validation and performance monitoring

  5. A time-domain method to generate artificial time history from a given reference response spectrum

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Gang Sik [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of); Song, Oh Seop [Dept. of Mechanical Engineering, Chungnam National University, Daejeon (Korea, Republic of)

    2016-06-15

    Seismic qualification by test is widely used as a way to show the integrity and functionality of equipment that is related to the overall safety of nuclear power plants. Another means of seismic qualification is by direct integration analysis. Both approaches require a series of time histories as an input. However, in most cases, the possibility of using real earthquake data is limited. Thus, artificial time histories are widely used instead. In many cases, however, response spectra are given. Thus, most of the artificial time histories are generated from the given response spectra. Obtaining the response spectrum from a given time history is straightforward. However, the procedure for generating artificial time histories from a given response spectrum is difficult and complex to understand. Thus, this paper presents a simple time-domain method for generating a time history from a given response spectrum; the method was shown to satisfy conditions derived from nuclear regulatory guidance.

  6. A time-domain method to generate artificial time history from a given reference response spectrum

    International Nuclear Information System (INIS)

    Shin, Gang Sik; Song, Oh Seop

    2016-01-01

    Seismic qualification by test is widely used as a way to show the integrity and functionality of equipment that is related to the overall safety of nuclear power plants. Another means of seismic qualification is by direct integration analysis. Both approaches require a series of time histories as an input. However, in most cases, the possibility of using real earthquake data is limited. Thus, artificial time histories are widely used instead. In many cases, however, response spectra are given. Thus, most of the artificial time histories are generated from the given response spectra. Obtaining the response spectrum from a given time history is straightforward. However, the procedure for generating artificial time histories from a given response spectrum is difficult and complex to understand. Thus, this paper presents a simple time-domain method for generating a time history from a given response spectrum; the method was shown to satisfy conditions derived from nuclear regulatory guidance

  7. Characterization of a new candidate isotopic reference material for natural Pb using primary measurement method.

    Science.gov (United States)

    Nonose, Naoko; Suzuki, Toshihiro; Shin, Ki-Cheol; Miura, Tsutomu; Hioki, Akiharu

    2017-06-29

    A lead isotopic standard solution with natural abundance has been developed by applying a mixture of a solution of enriched 208 Pb and a solution of enriched 204 Pb ( 208 Pb- 204 Pb double spike solution) as bracketing method. The amount-of-substance ratio of 208 Pb: 204 Pb in this solution is accurately measured by applying EDTA titrimetry, which is one of the primary measurement methods, to each enriched Pb isotope solution. Also metal impurities affecting EDTA titration and minor lead isotopes contained in each enriched Pb isotope solution are quantified by ICP-SF-MS. The amount-of-substance ratio of 208 Pb: 204 Pb in the 208 Pb- 204 Pb double spike solution is 0.961959 ± 0.000056 (combined standard uncertainty; k = 1). Both the measurement of lead isotope ratios in a candidate isotopic standard solution and the correction of mass discrimination in MC-ICP-MS are carried out by coupling of a bracketing method with the 208 Pb- 204 Pb double spike solution and a thallium internal addition method, where thallium solution is added to the standard and the sample. The measured lead isotope ratios and their expanded uncertainties (k = 2) in the candidate isotopic standard solution are 18.0900 ± 0.0046 for 206 Pb: 204 Pb, 15.6278 ± 0.0036 for 207 Pb: 204 Pb, 38.0626 ± 0.0089 for 208 Pb: 204 Pb, 2.104406 ± 0.00013 for 208 Pb: 206 Pb, and 0.863888 ± 0.000036 for 207 Pb: 206 Pb. The expanded uncertainties are about one half of the stated uncertainty for NIST SRM 981, for 208 Pb: 204 Pb, 207 Pb: 204 Pb and 206 Pb: 204 Pb, or one eighth, for 208 Pb: 206 Pb and 207 Pb: 206 Pb, The combined uncertainty consists of the uncertainties due to lead isotope ratio measurements and the remaining time-drift effect of mass discrimination in MC-ICP-MS, which is not removed by the coupled correction method. In the measurement of 208 Pb: 204 Pb, 207 Pb: 204 Pb and 206 Pb: 204 Pb, the latter contribution is two or three times larger than the former. When the coupling of

  8. 40 CFR 98.7 - What standardized methods are incorporated by reference into this part?

    Science.gov (United States)

    2010-07-01

    ... Hydraulic Cement, IBR approved for §§ 98.84(a), 98.84(b), and 98.84(c). (3) ASTM D235-02 (Reapproved 2007... Method for Density, Relative Density (Specific Gravity), or API Gravity of Crude Petroleum and Liquid..., Compressibility Factor, and Relative Density of Gaseous Fuels, IBR approved for §§ 98.34(a) and 98.254(e). (21...

  9. Evaluation of the Reference Numerical Parameters of the Monthly Method in ISO 13790 Considering S/V Ratio

    Directory of Open Access Journals (Sweden)

    Hee-Jeong Kwak

    2015-01-01

    Full Text Available Many studies have investigated the accuracy of the numerical parameters in the application of the quasi steady-state calculation method. The aim of this study is to derive the reference numerical parameters of the ISO 13790 monthly method by reflecting the surface-to-volume (S/V ratio and the characteristics of the structures. The calculation process was established, and the parameters necessary to derive the reference numerical parameters were calculated based on the input data prepared for the established calculation processes. The reference numerical parameters were then derived through regression analyses of the calculated parameters and the time constant. The parameters obtained from an apartment building and the parameters of the international standard were both applied to the Passive House Planning Package (PHPP and EnergyPlus programs, and the results were analyzed in order to evaluate the validity of the results. The analysis revealed that the calculation results based on the parameters derived from this study yielded lower error rates than those based on the default parameters in ISO 13790. However, the differences were shown to be negligible in the case of high heat capacity.

  10. A review of the methods for monitoring roe deer European populations with particular reference to Italy

    Directory of Open Access Journals (Sweden)

    Alberto Meriggi

    2009-02-01

    Full Text Available Abstract Throughout the last century, deer populations have shown a remarkable increase both in North America and Europe. As a consequence, the estimate of roe deer density has become a matter of interest. We reviewed the available literature on the methods used for monitoring roe deer populations in Europe from 1950 to 2004, with the aim of detecting the trend of papers and distribution of census techniques by years, countries and habitat types. Particular attention was paid to the census and monitoring methods adopted in Italy and Tuscany, which is the region where the roe deer is more carefully managed. Published papers showed an increasing trend, as did the number of methods used and their complexity. France, Italy, UK and Spain were the countries with the richest literature and the largest variety of methods applied. Eleven census methods have been applied in woods - particularly line transects, pellet group counts, CMR and IKA - with only 6 in open country, mainly pellet group counts. In Europe vantage points are more commonly used for planning culling programs, whilst in Italy, and particularly in Tuscany, the drive census and spotlight counts are mainly used. Unfortunately, in Europe, harvesting programs are still too much based on hunter knowledge and traditions. However the countries where the management of roe deer hunting is of more recent tradition make an exception to this rule. In Italy and Tuscany the methods of monitoring roe deer populations should be improved towards less expensive and more accurate methods. Riassunto Revisione dei metodi di monitoraggio delle popolazioni di capriolo in Europa con particolare riferimento all'Italia Le popolazioni di Cervidi hanno avuto nell'ultimo secolo un notevole incremento sia in America settentrionale, sia in Europa. Di conseguenza la densità delle popolazioni di capriolo è diventata oggetto di interessi diversi e la sua stima

  11. A Rapid Identification Method for Calamine Using Near-Infrared Spectroscopy Based on Multi-Reference Correlation Coefficient Method and Back Propagation Artificial Neural Network.

    Science.gov (United States)

    Sun, Yangbo; Chen, Long; Huang, Bisheng; Chen, Keli

    2017-07-01

    As a mineral, the traditional Chinese medicine calamine has a similar shape to many other minerals. Investigations of commercially available calamine samples have shown that there are many fake and inferior calamine goods sold on the market. The conventional identification method for calamine is complicated, therefore as a result of the large scale of calamine samples, a rapid identification method is needed. To establish a qualitative model using near-infrared (NIR) spectroscopy for rapid identification of various calamine samples, large quantities of calamine samples including crude products, counterfeits and processed products were collected and correctly identified using the physicochemical and powder X-ray diffraction method. The NIR spectroscopy method was used to analyze these samples by combining the multi-reference correlation coefficient (MRCC) method and the error back propagation artificial neural network algorithm (BP-ANN), so as to realize the qualitative identification of calamine samples. The accuracy rate of the model based on NIR and MRCC methods was 85%; in addition, the model, which took comprehensive multiple factors into consideration, can be used to identify crude calamine products, its counterfeits and processed products. Furthermore, by in-putting the correlation coefficients of multiple references as the spectral feature data of samples into BP-ANN, a BP-ANN model of qualitative identification was established, of which the accuracy rate was increased to 95%. The MRCC method can be used as a NIR-based method in the process of BP-ANN modeling.

  12. Advances in digital technology and orthodontics: a reference to the Invisalign method.

    Science.gov (United States)

    Melkos, Aristides B

    2005-05-01

    Increased aesthetic demands during orthodontic treatment resulted in several treatment alternatives. However, the need to avoid conventional fixed orthodontic appliances led, with the use of computer-aided scanning, imaging, and manufacturing technology, to the development of new therapy concepts such as Invisalign. The Invisalign orthodontic technique involves a series of clear removable appliances and has been applied to correct a variety of malocclusions. The Invisalign method is an aesthetic orthodontic option for many patients, but it is suited mainly to adults or adolescents who have a fully erupted dentition and it has its indications and limitations. It handles simple to moderate non-extraction alignments better than mild to moderate extraction cases. The aligners are clear and therefore aesthetically ideal for the patient; they are comfortable to wear and, as they are removable, they provide simplicity of care and better oral hygiene. They also allow the evaluation of treatment options in detail before beginning treatment by using a virtual treatment model. It is also important to point out that this method has some disadvantages, which are associated with patient compliance, limited control over specific tooth movements, and additional documentation time. The Invisalign concept is an aesthetic alternative in orthodontic treatment, with advantages and disadvantages. It can be utilized to treat simple to moderate alignment cases, especially in adults, and serves as an additional part of the armamentarium of the orthodontist.

  13. Standardization of glycohemoglobin results and reference values in whole blood studied in 103 laboratories using 20 methods.

    Science.gov (United States)

    Weykamp, C W; Penders, T J; Miedema, K; Muskiet, F A; van der Slik, W

    1995-01-01

    We investigated the effect of calibration with lyophilized calibrators on whole-blood glycohemoglobin (glyHb) results. One hundred three laboratories, using 20 different methods, determined glyHb in two lyophilized calibrators and two whole-blood samples. For whole-blood samples with low (5%) and high (9%) glyHb percentages, respectively, calibration decreased overall interlaboratory variation (CV) from 16% to 9% and from 11% to 6% and decreased intermethod variation from 14% to 6% and from 12% to 5%. Forty-seven laboratories, using 14 different methods, determined mean glyHb percentages in self-selected groups of 10 nondiabetic volunteers each. With calibration their overall mean (2SD) was 5.0% (0.5%), very close to the 5.0% (0.3%) derived from the reference method used in the Diabetes Control and Complications Trial. In both experiments the Abbott IMx and Vision showed deviating results. We conclude that, irrespective of the analytical method used, calibration enables standardization of glyHb results, reference values, and interpretation criteria.

  14. Recent applications of nuclear analytical methods to the certification of elemental content in NIST standard reference materials

    International Nuclear Information System (INIS)

    Greenberg, R.R.; Zeisler, R.; Mackey, E.A.

    2006-01-01

    Well-characterized, certified reference materials (CRMs) play an essential role in assuring the quality of analytical measurements. NIST has been producing CRMs, currently called NIST Standard Reference Materials (SRMs), to validate analytical measurements for nearly one hundred years. The predominant mode of certifying inorganic constituents in complex-matrix SRMs is through the use of two critically evaluated, independent analytical techniques at NIST. These techniques should have no significant sources of error in common. The use of nuclear analytical methods in combination with one of the chemically based analytical method at NIST eliminates the possibility of any significant, common error source. The inherent characteristics of the various forms of nuclear analytical methods make them extremely valuable for SRM certification. Instrumental NAA is nondestructive, which eliminates the possibility of any dissolution problems, and often provides homogeneity information. Radiochemical NAA typically provides nearly blank-free determinations of some highly important, but difficult elements at very low levels. Prompt-gamma NAA complements INAA, and provides independent determinations of some key elements. In addition, all significant uncertainty components can be evaluated for these techniques, and we believe these methods can meet all the requirements of a primary method of measurement as defined by ISO and the CCQM. NIST has certified several SRMs using INAA and RNAA as primary methods. In addition, NIST has compared measurements by INAA and PGAA with other primary methods as part of the CCQM intercomparisons of national metrology institutes. Some significant SRMs recently certified for inorganic constituents with contributions from the nuclear analytical methods include: Toxic Substances in Urine (SRM 2670a), Lake Superior Fish Tissue (SRM 1946), Air Particulate on Filter Media (SRM 2783), Inorganics in Marine Sediment (SRM 2702), Sediment for Solid Sampling (Small

  15. Reliability of different mark-recapture methods for population size estimation tested against reference population sizes constructed from field data.

    Directory of Open Access Journals (Sweden)

    Annegret Grimm

    Full Text Available Reliable estimates of population size are fundamental in many ecological studies and biodiversity conservation. Selecting appropriate methods to estimate abundance is often very difficult, especially if data are scarce. Most studies concerning the reliability of different estimators used simulation data based on assumptions about capture variability that do not necessarily reflect conditions in natural populations. Here, we used data from an intensively studied closed population of the arboreal gecko Gehyra variegata to construct reference population sizes for assessing twelve different population size estimators in terms of bias, precision, accuracy, and their 95%-confidence intervals. Two of the reference populations reflect natural biological entities, whereas the other reference populations reflect artificial subsets of the population. Since individual heterogeneity was assumed, we tested modifications of the Lincoln-Petersen estimator, a set of models in programs MARK and CARE-2, and a truncated geometric distribution. Ranking of methods was similar across criteria. Models accounting for individual heterogeneity performed best in all assessment criteria. For populations from heterogeneous habitats without obvious covariates explaining individual heterogeneity, we recommend using the moment estimator or the interpolated jackknife estimator (both implemented in CAPTURE/MARK. If data for capture frequencies are substantial, we recommend the sample coverage or the estimating equation (both models implemented in CARE-2. Depending on the distribution of catchabilities, our proposed multiple Lincoln-Petersen and a truncated geometric distribution obtained comparably good results. The former usually resulted in a minimum population size and the latter can be recommended when there is a long tail of low capture probabilities. Models with covariates and mixture models performed poorly. Our approach identified suitable methods and extended options to

  16. Comparison of two different segmentation methods on planar lung perfusion scan with reference to quantitative value on SPECT/CT

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Min Seok; Kang, Yeon Koo; Ha, Seung Gyun [Dept. of Nuclear Medicine, Seoul National University Hospital, Seoul (Korea, Republic of); and others

    2017-06-15

    Until now, there was no single standardized regional segmentation method of planar lung perfusion scan. We compared planar scan based two segmentation methods, which are frequently used in the Society of Nuclear Medicine, with reference to the lung perfusion single photon emission computed tomography (SPECT)/computed tomography (CT) derived values in lung cancer patients. Fifty-five lung cancer patients (male:female, 37:18; age, 67.8 ± 10.7 years) were evaluated. The patients underwent planar scan and SPECT/CT after injection of technetium-99 m macroaggregated albumin (Tc-99 m-MAA). The % uptake and predicted postoperative percentage forced expiratory volume in 1 s (ppoFEV1%) derived from both posterior oblique (PO) and anterior posterior (AP) methods were compared with SPECT/CT derived parameters. Concordance analysis, paired comparison, reproducibility analysis and spearman correlation analysis were conducted. The % uptake derived from PO method showed higher concordance with SPECT/CT derived % uptake in every lobe compared to AP method. Both methods showed significantly different lobar distribution of % uptake compared to SPECT/CT. For the target region, ppoFEV1% measured from PO method showed higher concordance with SPECT/CT, but lower reproducibility compared to AP method. Preliminary data revealed that every method significantly correlated with actual postoperative FEV1%, with SPECT/CT showing the best correlation. The PO method derived values showed better concordance with SPECT/CT compared to the AP method. Both PO and AP methods showed significantly different lobar distribution compared to SPECT/CT. In clinical practice such difference according to different methods and lobes should be considered for more accurate postoperative lung function prediction.

  17. Daily nursing feedback and discussion – a method to develop skills and augment quality and rehabilitative nursing for patients with spinal cord injury

    DEFF Research Database (Denmark)

    Steensgaard, Randi; Bonne, Stine

    2017-01-01

    Abstract Content: Background: Rehabilitation pathways for patients admitted with a spinal cord injury (SCI) are becoming increasingly complex, even as admission times are becoming shorter and more intensive. At the Spinal Cord Injury Centre of Western Denmark this means there is a growing need...... for sharing knowledge and experience to develop professional nursing skills in providing rehabilitative nursing care at the highest level, and in making a positive and valuable contribution to collaboration across professions. Aim: To improve knowledge, skills, and behaviour in rehabilitative nursing services...... to SCI patients through nursing feedback and discussion. Method: Four days each week, the nursing group meets for a 20-minute session of feedback and discussion on professional nursing issues, led by a session moderator. All nurses, whether new arrivals or experienced employees, have equal opportunity...

  18. Spatial Interpolation of Reference Evapotranspiration in India: Comparison of IDW and Kriging Methods

    Science.gov (United States)

    Hodam, Sanayanbi; Sarkar, Sajal; Marak, Areor G. R.; Bandyopadhyay, A.; Bhadra, A.

    2017-12-01

    In the present study, to understand the spatial distribution characteristics of the ETo over India, spatial interpolation was performed on the means of 32 years (1971-2002) monthly data of 131 India Meteorological Department stations uniformly distributed over the country by two methods, namely, inverse distance weighted (IDW) interpolation and kriging. Kriging was found to be better while developing the monthly surfaces during cross-validation. However, in station-wise validation, IDW performed better than kriging in almost all the cases, hence is recommended for spatial interpolation of ETo and its governing meteorological parameters. This study also checked if direct kriging of FAO-56 Penman-Monteith (PM) (Allen et al. in Crop evapotranspiration—guidelines for computing crop water requirements, Irrigation and drainage paper 56, Food and Agriculture Organization of the United Nations (FAO), Rome, 1998) point ETo produced comparable results against ETo estimated with individually kriged weather parameters (indirect kriging). Indirect kriging performed marginally well compared to direct kriging. Point ETo values were extended to areal ETo values by IDW and FAO-56 PM mean ETo maps for India were developed to obtain sufficiently accurate ETo estimates at unknown locations.

  19. Perturbational treatment of spin-orbit coupling for generally applicable high-level multi-reference methods

    Energy Technology Data Exchange (ETDEWEB)

    Mai, Sebastian; Marquetand, Philipp; González, Leticia [Institute of Theoretical Chemistry, University of Vienna, Währinger Str. 17, 1090 Vienna (Austria); Müller, Thomas, E-mail: th.mueller@fz-juelich.de [Institute for Advanced Simulation, Jülich Supercomputing Centre, Forschungszentrum Jülich, 52425 Jülich (Germany); Plasser, Felix [Interdisciplinary Center for Scientific Computing, University of Heidelberg, Im Neuenheimer Feld 368, 69120 Heidelberg (Germany); Lischka, Hans [Institute of Theoretical Chemistry, University of Vienna, Währinger Str. 17, 1090 Vienna (Austria); Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409-1061 (United States)

    2014-08-21

    An efficient perturbational treatment of spin-orbit coupling within the framework of high-level multi-reference techniques has been implemented in the most recent version of the COLUMBUS quantum chemistry package, extending the existing fully variational two-component (2c) multi-reference configuration interaction singles and doubles (MRCISD) method. The proposed scheme follows related implementations of quasi-degenerate perturbation theory (QDPT) model space techniques. Our model space is built either from uncontracted, large-scale scalar relativistic MRCISD wavefunctions or based on the scalar-relativistic solutions of the linear-response-theory-based multi-configurational averaged quadratic coupled cluster method (LRT-MRAQCC). The latter approach allows for a consistent, approximatively size-consistent and size-extensive treatment of spin-orbit coupling. The approach is described in detail and compared to a number of related techniques. The inherent accuracy of the QDPT approach is validated by comparing cuts of the potential energy surfaces of acrolein and its S, Se, and Te analoga with the corresponding data obtained from matching fully variational spin-orbit MRCISD calculations. The conceptual availability of approximate analytic gradients with respect to geometrical displacements is an attractive feature of the 2c-QDPT-MRCISD and 2c-QDPT-LRT-MRAQCC methods for structure optimization and ab inito molecular dynamics simulations.

  20. Perturbational treatment of spin-orbit coupling for generally applicable high-level multi-reference methods

    International Nuclear Information System (INIS)

    Mai, Sebastian; Marquetand, Philipp; González, Leticia; Müller, Thomas; Plasser, Felix; Lischka, Hans

    2014-01-01

    An efficient perturbational treatment of spin-orbit coupling within the framework of high-level multi-reference techniques has been implemented in the most recent version of the COLUMBUS quantum chemistry package, extending the existing fully variational two-component (2c) multi-reference configuration interaction singles and doubles (MRCISD) method. The proposed scheme follows related implementations of quasi-degenerate perturbation theory (QDPT) model space techniques. Our model space is built either from uncontracted, large-scale scalar relativistic MRCISD wavefunctions or based on the scalar-relativistic solutions of the linear-response-theory-based multi-configurational averaged quadratic coupled cluster method (LRT-MRAQCC). The latter approach allows for a consistent, approximatively size-consistent and size-extensive treatment of spin-orbit coupling. The approach is described in detail and compared to a number of related techniques. The inherent accuracy of the QDPT approach is validated by comparing cuts of the potential energy surfaces of acrolein and its S, Se, and Te analoga with the corresponding data obtained from matching fully variational spin-orbit MRCISD calculations. The conceptual availability of approximate analytic gradients with respect to geometrical displacements is an attractive feature of the 2c-QDPT-MRCISD and 2c-QDPT-LRT-MRAQCC methods for structure optimization and ab inito molecular dynamics simulations

  1. Using LMS Method in Smoothing Reference Centile Curves for Lipid Profile of Iranian Children and Adolescents: A CASPIAN Study

    Directory of Open Access Journals (Sweden)

    M Hoseini

    2012-05-01

    Full Text Available

    Background and Objectives: LMS is a general monitoring method for fitting smooth reference centile curves in medical sciences. They provide the distribution of a measurement as it changes according to some covariates like age or time. This method describes the distribution of changes by three parameters; Mean, Coefficient of variation and Cox-Box power (skewness. Applying maximum penalized likelihood and spline function, the three curves are estimated and fitted and optimum smoothness is expressed by three curves. This study was conducted to provide the percentiles of lipid profile of Iranian children and adolescents by LMS.

     

    Methods: Smoothed reference centile curves of four groups of lipids (triglycerides, total-LDL- and HDL-cholesterol were developed from the data of 4824 Iranian school students, aged 6-18 years, living in six cities (Tabriz, Rasht, Gorgan, Mashad, Yazd and Tehran-Firouzkouh in Iran. Demographic and laboratory data were taken from the national study of the surveillance and prevention of non-communicable diseases from childhood (CASPIAN Study. After data management, data of 4824 students were included in the statistical analysis, which was conducted by the modified LMS method proposed by Cole. The curves were developed with a degree of freedom of four to ten with some tools such as deviance, Q tests, and detrended Q-Q plot were used for monitoring goodness of fit models.

     

    Results: All tools confirmed the model, and the LMS method was used as an appropriate method in smoothing reference centile. This method revealed the distributing features of variables serving as an objective tool to determine their relative importance.

     

    Conclusion: This study showed that the triglycerides level is higher and

  2. Interpretation Problem of Czubek's Σa Measurement Method. Reference Experiment on H3BO3 Solutions

    International Nuclear Information System (INIS)

    Krynicka, E.; Gabanska, B.; Woznicka, U.; Dabrowska, J.; Burda, J.

    2001-12-01

    Czubek's method of measurement of the thermal neutron absorption cross section may be influenced by the energy spectrum of the thermal neutron flux (deviated from the Maxwellian distribution) which exist in the two-region geometric system. A correction function has been experimentally obtained to eliminate this disturbance. A series of reference measurements has been done on the H 3 BO 3 solution and Plexiglas outer moderator. The obtained function allows to interpret correctly measurements of the thermal neutron absorption rate in the range from 10 000 to 45 000 s -1 for hydrogenous samples. (author)

  3. Reference scenarios for deforestation and forest degradation in support of REDD: a review of data and methods

    International Nuclear Information System (INIS)

    Olander, Lydia P; Murray, Brian C; Gibbs, Holly K; Steininger, Marc; Swenson, Jennifer J

    2008-01-01

    Global climate policy initiatives are now being proposed to compensate tropical forest nations for reducing carbon emissions from deforestation and forest degradation (REDD). These proposals have the potential to include developing countries more actively in international greenhouse gas mitigation and to address a substantial share of the world's emissions which come from tropical deforestation. For such a policy to be viable it must have a credible benchmark against which emissions reduction can be calculated. This benchmark, sometimes termed a baseline or reference emissions scenario, can be based directly on historical emissions or can use historical emissions as input for business as usual projections. Here, we review existing data and methods that could be used to measure historical deforestation and forest degradation reference scenarios including FAO (Food and Agricultural Organization of the United Nations) national statistics and various remote sensing sources. The freely available and corrected global Landsat imagery for 1990, 2000 and soon to come for 2005 may be the best primary data source for most developing countries with other coarser resolution high frequency or radar data as a valuable complement for addressing problems with cloud cover and for distinguishing larger scale degradation. While sampling of imagery has been effectively useful for pan-tropical and continental estimates of deforestation, wall-to-wall (or full coverage) allows more detailed assessments for measuring national-level reference emissions. It is possible to measure historical deforestation with sufficient certainty for determining reference emissions, but there must be continued calls at the international level for making high-resolution imagery available, and for financial and technical assistance to help countries determine credible reference scenarios. The data available for past years may not be sufficient for assessing all forms of forest degradation, but new data sources

  4. Utility of Penman-Monteith, Priestley-Taylor, reference evapotranspiration, and pan evaporation methods to estimate pasture evapotranspiration

    Science.gov (United States)

    Sumner, D.M.; Jacobs, J.M.

    2005-01-01

    Actual evapotranspiration (ETa) was measured at 30-min resolution over a 19-month period (September 28, 2000-April 23, 2002) from a nonirrigated pasture site in Florida, USA, using eddy correlation methods. The relative magnitude of measured ETa (about 66% of long-term annual precipitation at the study site) indicates the importance of accurate ET a estimates for water resources planning. The time and cost associated with direct measurements of ETa and the rarity of historical measurements of ETa make the use of methods relying on more easily obtainable data desirable. Several such methods (Penman-Monteith (PM), modified Priestley-Taylor (PT), reference evapotranspiration (ET 0), and pan evaporation (Ep)) were related to measured ETa using regression methods to estimate PM bulk surface conductance, PT ??, ET0 vegetation coefficient, and Ep pan coefficient. The PT method, where the PT ?? is a function of green-leaf area index (LAI) and solar radiation, provided the best relation with ET a (standard error (SE) for daily ETa of 0.11 mm). The PM method, in which the bulk surface conductance was a function of net radiation and vapor-pressure deficit, was slightly less effective (SE=0.15 mm) than the PT method. Vegetation coefficients for the ET0 method (SE=0.29 mm) were found to be a simple function of LAI. Pan coefficients for the Ep method (SE=0.40 mm) were found to be a function of LAI and Ep. Historical or future meteorological, LAI, and pan evaporation data from the study site could be used, along with the relations developed within this study, to provide estimates of ETa in the absence of direct measurements of ETa. Additionally, relations among PM, PT, and ET0 methods and ETa can provide estimates of ETa in other, environmentally similar, pasture settings for which meteorological and LAI data can be obtained or estimated. ?? 2004 Elsevier B.V. All rights reserved.

  5. An internal reference model-based PRF temperature mapping method with Cramer-Rao lower bound noise performance analysis.

    Science.gov (United States)

    Li, Cheng; Pan, Xinyi; Ying, Kui; Zhang, Qiang; An, Jing; Weng, Dehe; Qin, Wen; Li, Kuncheng

    2009-11-01

    The conventional phase difference method for MR thermometry suffers from disturbances caused by the presence of lipid protons, motion-induced error, and field drift. A signal model is presented with multi-echo gradient echo (GRE) sequence using a fat signal as an internal reference to overcome these problems. The internal reference signal model is fit to the water and fat signals by the extended Prony algorithm and the Levenberg-Marquardt algorithm to estimate the chemical shifts between water and fat which contain temperature information. A noise analysis of the signal model was conducted using the Cramer-Rao lower bound to evaluate the noise performance of various algorithms, the effects of imaging parameters, and the influence of the water:fat signal ratio in a sample on the temperature estimate. Comparison of the calculated temperature map and thermocouple temperature measurements shows that the maximum temperature estimation error is 0.614 degrees C, with a standard deviation of 0.06 degrees C, confirming the feasibility of this model-based temperature mapping method. The influence of sample water:fat signal ratio on the accuracy of the temperature estimate is evaluated in a water-fat mixed phantom experiment with an optimal ratio of approximately 0.66:1. (c) 2009 Wiley-Liss, Inc.

  6. The upper reference limit for thyroid peroxidase autoantibodies is method-dependent: A collaborative study with biomedical industries.

    Science.gov (United States)

    Tozzoli, Renato; D'Aurizio, Federica; Ferrari, Anna; Castello, Roberto; Metus, Paolo; Caruso, Beatrice; Perosa, Anna Rosa; Sirianni, Francesca; Stenner, Elisabetta; Steffan, Agostino; Villalta, Danilo

    2016-01-15

    The determination of the upper reference limit (URL) for thyroid peroxidase autoantibodies (TPOAbs) is a contentious issue, because of the difficulty in defining the reference population. The aim of this study was to establish the URL (eURL) for TPOAbs, according to the National Academy of Clinical Biochemistry (NACB) guidelines and to compare them with those obtained in a female counterpart, by the use of six commercial automated platforms. 120 healthy males and 120 healthy females with NACB-required characteristics (Lumipulse G1200, Fujirebio. Within each method, TPOAbs values had a high degree of dispersion and the eURLs were lower than those stated by the manufacturer. A statistically significant difference (p0.05). Despite the analytical harmonization, the wide dispersion of the results and the differences of the eURLs between methods suggest the need of further studies focusing on TPO antigen preparations as the possible source of variability between different assays. In addition, the lack of clinical significant difference between males and females, in terms of TPOAb eURLs, confirms the suitability of the NACB recommendations. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Development of liquid chromatographic methods for the determination of phytosterols in Standard Reference Materials containing saw palmetto.

    Science.gov (United States)

    Bedner, Mary; Schantz, Michele M; Sander, Lane C; Sharpless, Katherine E

    2008-05-23

    Liquid chromatographic (LC) methods using atmospheric pressure chemical ionization/mass spectrometric (APCI-MS) detection were developed for the separation and analysis of the phytosterols campesterol, cycloartenol, lupenone, lupeol, beta-sitosterol, and stigmasterol. Brassicasterol and cholesterol were also included for investigation as internal standards. The methods were used to identify and quantify the phytosterols in each of two Serenoa repens (saw palmetto) Standard Reference Materials (SRMs) developed by the National Institute of Standards and Technology (NIST). Values obtained by LC-MS were compared to those obtained using the more traditional approach of gas chromatography with flame ionization detection. This is the first reported use of LC-MS to determine phytosterols in saw palmetto dietary supplement materials.

  8. IMPROVING THE STUDENTS’ COMPETENCE IN DEVELOPING A PARAGRAPH OF DISCUSSION TEXTS USING THEMATIC PROGRESSION PATTERNS WITH COOPERATIVE LEARNING METHOD (TP-CL

    Directory of Open Access Journals (Sweden)

    Farikah Farikah

    2017-04-01

    Full Text Available This research analyzes the effectiveness of thematic progression patterns with cooperative learning method (TP-CL in teaching the students’ competence in developing a paragraph of discussion texts and the effectiveness of teaching-learning activities of paragraph writing class. This mixed method research was conducted in the English Department of Tidar University of Magelang in the academic year of 2011/2012. The sample of this research were the fourth semester students of UTM. To collect the research data, writing test, observation and interview were used while to analyze the data, she used descriptive and inferential statistics for quantitative data and constant comparative method for qualitative data. The first result shows that implementing TP-CL is effective for teaching the students’ competence in developing a paragraph of discussion texts. It can be seen from the results of writing tests. Based on Brown and Bailey’s theory in Brown (2004, it can be seen that the mean score of organization element in pretest is 10.77 and the post test of paragraph writing is 16.73. The second result shows that there is an improvement of the effectiveness of teaching-learning activity of writing class by implementing TP-CL. The effectiveness can be seen from the indicators of effective teaching based on Blum in Nunan and Lamb (1996 and Creemer’s theory (1994. The results suggest that writing lecturers should introduce to develop a paragraph to the students in order that they can write paragraphs coherently and various theme in order that they can write the paragraph artistically.

  9. Discuss on luminescence dose data analysis technology

    International Nuclear Information System (INIS)

    Ma Xinhua; Xiao Wuyun; Ai Xianyun; Shi Zhilan; Liu Ying

    2009-01-01

    This article describes the development of luminescence dose data measurement and processing technology. General design planning of luminescence dose data measurement and processing technology is put forward with the diverse demands. The emphasis is focused on dose data processing method, luminescence curve analysis method, using of network, mechanics of communication among computers, data base management system of individual dose in this paper. The main methods and skills used in this technology as well as their advantages are also discussed. And it offers general design references for development luminescence dose data processing software. (authors)

  10. A calibration method for the measurement of IR detector spectral responses using a FTIR spectrometer equipped with a DTGS reference cell

    Science.gov (United States)

    Gravrand, Olivier; Wlassow, J.; Bonnefond, L.

    2014-07-01

    transfert function of the DTGS has to be qualified and taken into account. The usual way is to measure it directly by means of an optical shopper and a locking amplifier for different shopping frequencies. We present here an alternative method to estimate this DTGS transfer function, based on the fact that a FTIR continuous scan interfergram contains the different spectral frequencies of interest. Such a calibration method doesn't need a specific setup as it can be performed in standard configuration, playing only with spectrometer parameters. It allows for the precise estimation of detector spectral shapes. However, this measurement is not absolute and the peak response needs therefore to be estimated using a calibrated black body cavity. The method, its results and limits is presented and discussed for a set of different DTGS cells.

  11. Comparison of platelet counts by sysmex XE 2100 and LH-750 with the international flow reference method in thrombocytopenic patients

    Directory of Open Access Journals (Sweden)

    Tina Dadu

    2013-01-01

    Full Text Available Background: There are several methods for counting platelets, of which the international flow reference method (IRM is considered to be the gold standard. We compared the platelet count given by this method to the count given by automated analyzers using other methods, such as optical fluorescence and impedance. Aims: The aim of this study is to compare the platelet counts obtained by Sysmex XE 2100 by Impedance (Sysmex-I, optical florescence (Sysmex-O and reported (Sysmex-R based on the switching algorithm and LH-750 by Impedance (LH-750 with the IRM in thrombocytopenic blood samples. To calculate the sensitivity, specificity, positive predictive value (PPV and negative predictive value (NPV of various technologies at the clinically relevant transfusion thresholds of 10 × 10 9 /l and 20 × 10 9 /l. Materials and Methods: A total of 118 blood samples with platelet count of <50 × 10 9 /l were selected for the study. Platelet counts of all samples were analyzed by all methods using the Sysmex analyzer, LH-750 and IRM in parallel within 6 h of collection. Statistical Analysis Used: Pearson correlation, bland Altman analysis, sensitivity and specificity, PPV and NPV. Results and Conclusions: Sysmex-R had the least Bias and 95% limits of agreement (95%LA range and thus correlated best with IRM values. LH-750 had a higher Bias compared to Sysmex-O and Sysmex-R, but a strikingly similar 95% LA ensures similar results in all three methods. In fact, in the oncology subset, it had the narrowest 95% LA, which made it the best performer in this subgroup. Of the three Sysmex results, Sysmex-I had the highest bias, widest 95% LA and highest potential risk of over transfusion. Hence, Sysmex-R and LH-750 were found to be reliable tools for estimation of platelet count in thrombocytopenic patients.

  12. A novel method of calibrating a MEMS inertial reference unit on a turntable under limited working conditions

    Science.gov (United States)

    Lu, Jiazhen; Liang, Shufang; Yang, Yanqiang

    2017-10-01

    Micro-electro-mechanical systems (MEMS) inertial measurement devices tend to be widely used in inertial navigation systems and have quickly emerged on the market due to their characteristics of low cost, high reliability and small size. Calibration is the most effective way to remove the deterministic error of an inertial reference unit (IRU), which in this paper consists of three orthogonally mounted MEMS gyros. However, common testing methods in the lab cannot predict the corresponding errors precisely when the turntable’s working condition is restricted. In this paper, the turntable can only provide a relatively small rotation angle. Moreover, the errors must be compensated exactly because of the great effect caused by the high angular velocity of the craft. To deal with this question, a new method is proposed to evaluate the MEMS IRU’s performance. In the calibration procedure, a one-axis table that can rotate a limited angle in the form of a sine function is utilized to provide the MEMS IRU’s angular velocity. A new algorithm based on Fourier series is designed to calculate the misalignment and scale factor errors. The proposed method is tested in a set of experiments, and the calibration results are compared to a traditional calibration method performed under normal working conditions to verify their correctness. In addition, a verification test in the given rotation speed is implemented for further demonstration.

  13. Revising shortwave and longwave radiation archives in view of possible revisions of the WSG and WISG reference scales: methods and implications

    Science.gov (United States)

    Nyeki, Stephan; Wacker, Stefan; Gröbner, Julian; Finsterle, Wolfgang; Wild, Martin

    2017-08-01

    A large number of radiometers are traceable to the World Standard Group (WSG) for shortwave radiation and the interim World Infrared Standard Group (WISG) for longwave radiation, hosted by the Physikalisch-Meteorologisches Observatorium Davos/World Radiation Centre (PMOD/WRC, Davos, Switzerland). The WSG and WISG have recently been found to over- and underestimate radiation values, respectively (Fehlmann et al., 2012; Gröbner et al., 2014), although research is still ongoing. In view of a possible revision of the reference scales of both standard groups, this study discusses the methods involved and the implications on existing archives of radiation time series, such as the Baseline Surface Radiation Network (BSRN). Based on PMOD/WRC calibration archives and BSRN data archives, the downward longwave radiation (DLR) time series over the 2006-2015 period were analysed at four stations (polar and mid-latitude locations). DLR was found to increase by up to 3.5 and 5.4 W m-2 for all-sky and clear-sky conditions, respectively, after applying a WISG reference scale correction and a minor correction for the dependence of pyrgeometer sensitivity on atmospheric integrated water vapour content. Similar increases in DLR may be expected at other BSRN stations. Based on our analysis, a number of recommendations are made for future studies.

  14. Determinations of silicon and phosphorus in Pepperbush standard reference material by neutron activation and x-ray fluorescence methods

    International Nuclear Information System (INIS)

    Mizumoto, Yoshihiko; Nishio, Hirofumi; Hayashi, Takeshi; Kusakabe, Toshio; Iwata, Shiro.

    1987-01-01

    Silicon and phosphorus contents in Pepperbush standard reference material were determined by neutron activation and X-ray fluorescence methods. In neutron activation analysis, β-ray spectra of 32 P produced by 31 P(n,γ) 32 P reaction on Pepperbush and standard samples were measured by a low background β-ray spectrometer. In X-ray fluorescence analysis, the standard samples were prepared by mixing the Pepperbush powder with silicon dioxide and diammonium hydrogenphosphate. Characteristic X-rays from the samples were analyzed by a wavelength dispersive X-ray fluorescence spectrometer. From the β and X-ray intensities, silicon and phosphorus contents in Pepperbush were determined to be 1840 ± 80 and 1200 ± 50 μg g -1 , respectively. (author)

  15. REFERENCE MATERIALS SYSTEM OF SCIENTIFIC METHODICAL CENTRE OF STATE SERVICE OF REFERENCE MATERIALS FOR COMPOSITION AND PROPERTIES OF SUBSTANCES AND MATERIALS URAL RESEARCH INSTITUTE FOR METROLOGY

    Directory of Open Access Journals (Sweden)

    E. V. Osinseva

    2015-01-01

    Full Text Available Since 1960s UNIIM performs research in the field of needs in reference materials of composition and properties of substances and materials (RM as well as develops it. During the research UNIIM has developed 757 types of RMs for metrological measurement assurance of factors of composition and properties of substance and materials for test laboratories of chemical, pharmaceutical, fuel, food industry, agriculture, metallurgy and ecological monitoring laboratories. List ofRMs enlarges thanks to development of UNIIM standards and transmission measurement facility from State standards of units. Taking into account the actual requirements in the field of measurements, the UNIIM's key destination is to assure the accuracy and the metrological traceability of measurements. The present-day system of RMs to be developed in UNIIM includes RMs of composition of inorganic and organic compounds and their solutions, fuels, stable isotopic materials, water, grounds, food products, biomaterials, nanomaterials, metals, alloys and other materials offerrous and non-ferrous industry, RMs of properties (thermodynamic, magnetic, physical-chemical, technical of substances and materials. The present article considers history of RMs list development which were created by UNIIM and the strategy of this direction.

  16. Task-oriented comparison of power spectral density estimation methods for quantifying acoustic attenuation in diagnostic ultrasound using a reference phantom method.

    Science.gov (United States)

    Rosado-Mendez, Ivan M; Nam, Kibo; Hall, Timothy J; Zagzebski, James A

    2013-07-01

    Reported here is a phantom-based comparison of methods for determining the power spectral density (PSD) of ultrasound backscattered signals. Those power spectral density values are then used to estimate parameters describing α(f), the frequency dependence of the acoustic attenuation coefficient. Phantoms were scanned with a clinical system equipped with a research interface to obtain radiofrequency echo data. Attenuation, modeled as a power law α(f)= α0 f (β), was estimated using a reference phantom method. The power spectral density was estimated using the short-time Fourier transform (STFT), Welch's periodogram, and Thomson's multitaper technique, and performance was analyzed when limiting the size of the parameter-estimation region. Errors were quantified by the bias and standard deviation of the α0 and β estimates, and by the overall power-law fit error (FE). For parameter estimation regions larger than ~34 pulse lengths (~1 cm for this experiment), an overall power-law FE of 4% was achieved with all spectral estimation methods. With smaller parameter estimation regions as in parametric image formation, the bias and standard deviation of the α0 and β estimates depended on the size of the parameter estimation region. Here, the multitaper method reduced the standard deviation of the α0 and β estimates compared with those using the other techniques. The results provide guidance for choosing methods for estimating the power spectral density in quantitative ultrasound methods.

  17. Precision of glucose measurements in control sera by isotope dilution/mass spectrometry: proposed definitive method compared with a reference method

    International Nuclear Information System (INIS)

    Pelletier, O.; Arratoon, C.

    1987-01-01

    This improved isotope-dilution gas chromatographic/mass spectrometric (GC/MS) method, in which [ 13 C]glucose is the internal standard, meets the requirements of a Definitive Method. In a first study with five reconstituted lyophilized sera, a nested analysis of variance of GC/MS values indicated considerable among-vial variation. The CV for 32 measurements per serum ranged from 0.5 to 0.9%. However, concentration and uncertainty values (mmol/L per gram of serum) assigned to one serum by the NBS Definitive Method (7.56 +/- 0.28) were practically identical to those obtained with the proposed method (7.57 +/- 0.20). In the second study, we used twice more [ 13 C]glucose diluent to assay four serum pools and two lyophilized sera. The CV ranged from 0.26 to 0.5% for the serum pools and from 0.28 to 0.59% for the lyophilized sera. In comparison, results by the hexokinase/glucose-6-phosphate dehydrogenase reference method agreed within acceptable limits with those by the Definitive Method but tended to be slightly higher (up to 3%) for lyophilized serum samples or slightly lower (up to 2.5%) for serum pools

  18. A comparative uncertainty study of the calibration of macrolide antibiotic reference standards using quantitative nuclear magnetic resonance and mass balance methods

    International Nuclear Information System (INIS)

    Liu Shuyu; Hu Changqin

    2007-01-01

    This study introduces the general method of quantitative nuclear magnetic resonance (qNMR) for the calibration of reference standards of macrolide antibiotics. Several qNMR experimental conditions were optimized including delay, which is an important parameter of quantification. Three kinds of macrolide antibiotics were used to validate the accuracy of the qNMR method by comparison with the results obtained by the high performance liquid chromatography (HPLC) method. The purities of five common reference standards of macrolide antibiotics were measured by the 1 H qNMR method and the mass balance method, respectively. The analysis results of the two methods were compared. The qNMR is quick and simple to use. In a new medicine research and development process, qNMR provides a new and reliable method for purity analysis of the reference standard

  19. Improvement of the banana "Musa acuminata" reference sequence using NGS data and semi-automated bioinformatics methods.

    Science.gov (United States)

    Martin, Guillaume; Baurens, Franc-Christophe; Droc, Gaëtan; Rouard, Mathieu; Cenci, Alberto; Kilian, Andrzej; Hastie, Alex; Doležel, Jaroslav; Aury, Jean-Marc; Alberti, Adriana; Carreel, Françoise; D'Hont, Angélique

    2016-03-16

    Recent advances in genomics indicate functional significance of a majority of genome sequences and their long range interactions. As a detailed examination of genome organization and function requires very high quality genome sequence, the objective of this study was to improve reference genome assembly of banana (Musa acuminata). We have developed a modular bioinformatics pipeline to improve genome sequence assemblies, which can handle various types of data. The pipeline comprises several semi-automated tools. However, unlike classical automated tools that are based on global parameters, the semi-automated tools proposed an expert mode for a user who can decide on suggested improvements through local compromises. The pipeline was used to improve the draft genome sequence of Musa acuminata. Genotyping by sequencing (GBS) of a segregating population and paired-end sequencing were used to detect and correct scaffold misassemblies. Long insert size paired-end reads identified scaffold junctions and fusions missed by automated assembly methods. GBS markers were used to anchor scaffolds to pseudo-molecules with a new bioinformatics approach that avoids the tedious step of marker ordering during genetic map construction. Furthermore, a genome map was constructed and used to assemble scaffolds into super scaffolds. Finally, a consensus gene annotation was projected on the new assembly from two pre-existing annotations. This approach reduced the total Musa scaffold number from 7513 to 1532 (i.e. by 80%), with an N50 that increased from 1.3 Mb (65 scaffolds) to 3.0 Mb (26 scaffolds). 89.5% of the assembly was anchored to the 11 Musa chromosomes compared to the previous 70%. Unknown sites (N) were reduced from 17.3 to 10.0%. The release of the Musa acuminata reference genome version 2 provides a platform for detailed analysis of banana genome variation, function and evolution. Bioinformatics tools developed in this work can be used to improve genome sequence assemblies in

  20. Determination of uncertainty of automated emission measuring systems under field conditions using a second method as a reference

    Energy Technology Data Exchange (ETDEWEB)

    Puustinen, H.; Aunela-Tapola, L.; Tolvanen, M.; Vahlman, T. [VTT Chemical Technology, Espoo (Finland). Environmental Technology; Kovanen, K. [VTT Building Technology, Espoo (Finland). Building Physics, Building Services and Fire Technology

    1999-09-01

    This report presents a procedure to determine the uncertainty of an automated emission measuring system (AMS) by comparing the results with a second method (REF). The procedure determines the uncertainty of AMS by comparing the final concentration and emission results of AMS and REF. In this way, the data processing of the plant is included in the result evaluation. This procedure assumes that the uncertainty of REF is known and determined in due form. The uncertainty determination has been divided into two cases; varying and nearly constant concentration. The suggested procedure calculates the uncertainty of AMS at the 95 % confidence level by a tabulated t-value. A minimum of three data pairs is required. However, a higher amount of data pairs is desirable, since a low amount of data pairs results in a higher uncertainty of AMS. The uncertainty of AMS is valid only within the range of concentrations at which the tests were carried out. Statistical data processing shows that the uncertainty of the reference method has a significant effect on the uncertainty of AMS, which always becomes larger than the uncertainty of REF. This should be taken into account when testing whether AMS fulfils the given uncertainty limits. Practical details, concerning parallel measurements at the plant, and the costs of the measurement campaign, have been taken into account when suggesting alternative ways for implementing the comparative measurements. (orig.) 6 refs.

  1. Enterprise Reference Library

    Science.gov (United States)

    Bickham, Grandin; Saile, Lynn; Havelka, Jacque; Fitts, Mary

    2011-01-01

    Introduction: Johnson Space Center (JSC) offers two extensive libraries that contain journals, research literature and electronic resources. Searching capabilities are available to those individuals residing onsite or through a librarian s search. Many individuals have rich collections of references, but no mechanisms to share reference libraries across researchers, projects, or directorates exist. Likewise, information regarding which references are provided to which individuals is not available, resulting in duplicate requests, redundant labor costs and associated copying fees. In addition, this tends to limit collaboration between colleagues and promotes the establishment of individual, unshared silos of information The Integrated Medical Model (IMM) team has utilized a centralized reference management tool during the development, test, and operational phases of this project. The Enterprise Reference Library project expands the capabilities developed for IMM to address the above issues and enhance collaboration across JSC. Method: After significant market analysis for a multi-user reference management tool, no available commercial tool was found to meet this need, so a software program was built around a commercial tool, Reference Manager 12 by The Thomson Corporation. A use case approach guided the requirements development phase. The premise of the design is that individuals use their own reference management software and export to SharePoint when their library is incorporated into the Enterprise Reference Library. This results in a searchable user-specific library application. An accompanying share folder will warehouse the electronic full-text articles, which allows the global user community to access full -text articles. Discussion: An enterprise reference library solution can provide a multidisciplinary collection of full text articles. This approach improves efficiency in obtaining and storing reference material while greatly reducing labor, purchasing and

  2. Proposal of reference stress for a surface flaw on a cylindrical component from a review-with-comparison of the local metal loss assessment rule between API 579-1 and the p-M diagram method

    International Nuclear Information System (INIS)

    Oyamada, Kenji; Konosu, Shinji; Ohno, Takashi

    2011-01-01

    The Remaining Strength Factor (RSF) approach in Part 5 of API 579-1/ASME FFS-1 is an assessment method for a cylindrical component with a local metal loss based on surface correction factors. Also, reference stress solutions that are applied in the Failure Assessment Diagram (FAD) method for a cylindrical component with a crack-like flaw are provided in Annex D using surface correction factors. In the recently-developed p-M diagram method, the reference stress solution for local metal loss evaluation in a cylindrical component is derived using bulging factors, which are similar but not identical to the surface correction factors used in API 579-1/ASME FFS-1. This paper describes the results of a comparative study among the RSF approach, reference stress solutions for the FAD method, and the p-M diagram method, in terms of plastic collapse evaluation of a cylindrical component. These results were compared with the FEA and experimental results to confirm how these estimated stresses could be validated. This study also involves recommended reference stress solutions for a cylindrical component with a crack-like flaw or a local metal loss, which should be adopted as fitness-for-service rules, and a discussion on the influence of the design margin of the construction code on allowable flaw depth. - Highlights: → We compared local metal loss assessment rule between API 579-1 and the p-M method. → Experiments and FEA verified the p-M estimate stress state around a flaw accurate. → API 579-1 for local metal loss may underestimate stress state for certain conditions. → Existing reference stresses for crack-like flaws may underestimate stress state too. → We propose the reference stress for a surface flaw subjected to pressure and moment.

  3. X-points in the spectral emissivity of solid and liquid refractory transition metals measured by multichannel pyrometry. Discussion of the experimental method and physical interpretation

    International Nuclear Information System (INIS)

    Ronchi, C.; Hiernaut, J.P.; Hyland, G.J.

    1993-01-01

    The spectral emissivities of some refractory Transition metals (Hf, Mo, Nb, Re, V, W and Zr) have been measured from about 2500 K up to temperatures above the melting point T m . The experimental method adopted is based on multiwavelength pyrometric measurements, where the determination of the spectral emissivity is implicitly related to the evaluation of temperature through the radiation emission law and an assumed relationship between the spectral emissivity ε and the wavelength λ. Heating was produced with a pulsed laser in times of the order of 100 ms. A specially constructed pyrometer was used which enabled measurements at six different wavelengths to be carried out at time intervals of the order of 0.1 ms. A model for the evaluation of temperature and spectral emissivities has been developed and its limitations due to statistical and systematic errors are discussed. Our experiments confirm the existence of a unique wavelength, λ-x for each metal to which different ε λ -isotherms converge for λ x and from which they diverge for λ>λ x and at which ε λ is independent of T, and thus equal, in particular, to its value at T m , indicate that λ x is preserved through T m and reveal that at T m these metals are effectively 'grey'. Detailed theoretical investigations reveal that the occurrence of the λ x points is intimately connected with the particular T and λ dependences of the interband contribution to the imaginary part of the complex dielectric function entailed by specific features of the electronic band-structure of the Transition metals concerned. Finally, in connection with the 'grey' phenomenon at T m , it should be stressed that this is not found in the case of the Noble metals, although, like Transition metals, they exhibit λ x points, despite their quite different band-structures. (author). 56 refs., 8 figs., 5 tabs

  4. Modeling plant density and ponding water effects on flooded rice evapotranspiration and crop coefficients: critical discussion about the concepts used in current methods

    Science.gov (United States)

    Aschonitis, Vassilis; Diamantopoulou, Maria; Papamichail, Dimitris

    2018-05-01

    The aim of the study is to propose new modeling approaches for daily estimations of crop coefficient K c for flooded rice ( Oryza sativa L., ssp. indica) under various plant densities. Non-linear regression (NLR) and artificial neural networks (ANN) were used to predict K c based on leaf area index LAI, crop height, wind speed, water albedo, and ponding water depth. Two years of evapotranspiration ET c measurements from lysimeters located in a Mediterranean environment were used in this study. The NLR approach combines bootstrapping and Bayesian sensitivity analysis based on a semi-empirical formula. This approach provided significant information about the hidden role of the same predictor variables in the Levenberg-Marquardt ANN approach, which improved K c predictions. Relationships of production versus ET c were also built and verified by data obtained from Australia. The results of the study showed that the daily K c values, under extremely high plant densities (e.g., for LAI max > 10), can reach extremely high values ( K c > 3) during the reproductive stage. Justifications given in the discussion question both the K c values given by FAO and the energy budget approaches, which assume that ET c cannot exceed a specific threshold defined by the net radiation. These approaches can no longer explain the continuous increase of global rice yields (currently are more than double in comparison to the 1960s) due to the improvement of cultivars and agriculture intensification. The study suggests that the safest method to verify predefined or modeled K c values is through preconstructed relationships of production versus ET c using field measurements.

  5. Use of stable isotopes method in hydrological investigations with special reference to studies in Lower Maner Basin, Andhra Pradesh

    International Nuclear Information System (INIS)

    Kumar, B.; Athavale, R.N.; Sahay, K.S.N.

    1982-01-01

    The study of variations of stable isotope ratios in water is becoming increasingly important in hydrological investigations and is being widely used for: (i) characterizing water masses and indicating their origin, (ii) finding interconnection of water bodies, (iii) estimating leakages for reservoirs, (iv) water balances studies of lakes, (v) glaciological studies, etc. This paper briefly describes the principle of the method and details of isotope ratio measurement techniques used at the National Geophysical Research Institute, Hyderabad. Integrated geohydrological investigations comprising photogeological, hydrogeochemical, geophysical, nuclear and modelling studies have been carried out in the Lower Maner Basin, A.P., under an Indo-German collaboration project. As a part of this programme,, precipitation, surface and sub-surface water samples from the basin were analysed for their D:H and O 18 :O 16 ratios. The results of these measurements are presented and discussed. (author)

  6. Hg0 and HgCl2 Reference Gas Standards: NIST Traceability and Comparability (And EPA ALT Methods for Hg and HCl )

    Science.gov (United States)

    EPA and NIST have collaborated to establish the necessary procedures for establishing the required NIST traceability of commercially-provided Hg0 and HgCl2 reference generators. This presentation will discuss the approach of a joint EPA/NIST study to accurately quantify the tru...

  7. Testing the causal theory of reference.

    Science.gov (United States)

    Domaneschi, Filippo; Vignolo, Massimiliano; Di Paola, Simona

    2017-04-01

    Theories of reference are a crucial research topic in analytic philosophy. Since the publication of Kripke's Naming and Necessity, most philosophers have endorsed the causal/historical theory of reference. The goal of this paper is twofold: (i) to discuss a method for testing experimentally the causal theory of reference for proper names by investigating linguistic usage and (ii) to present the results from two experiments conducted with that method. Data collected in our experiments confirm the causal theory of reference for people proper names and for geographical proper names. A secondary but interesting result is that the semantic domain affects reference assignment: while with people proper names speakers tend to assign the semantic reference, with geographical proper names they are prompted to assign the speaker's reference. Copyright © 2016 Elsevier B.V. All rights reserved.

  8. Analysis of Reference Cigarette Smoke Yield Data From 21 Laboratories for 28 Selected Analytes as a Guide to Selection of New Coresta Recommended Methods

    Directory of Open Access Journals (Sweden)

    Purkis Steve

    2014-07-01

    Full Text Available Since 1999, the CORESTA Special Analytes Sub Group (SPA SG has been working on the development of CORESTA Recommended Methods (CRMs for the analysis of cigarette smoke components. All CRMs have been posted on the CORESTA website and several associated papers published. In this study, 21 laboratories shared data and in-house methodologies for 28 additional smoke components of regulatory interest to prioritise the development of further CRMs. Laboratories provided data, where available, from CORESTA monitor test pieces (CM6 and CM7 and Kentucky Reference Cigarettes (1R5F / 3R4F covering the period 2010-2012 obtained under both the ISO 3308 and Health Canada Intense regimes. Scant data were available on the CORESTA monitor test pieces and the Kentucky 1R5F reference. The greatest amount of data was obtained on the Kentucky 3R4F and this was used in the analyses described in this paper. SPA SG discussions provided invaluable insight into identifying causes and ways of reducing inter-laboratory variability which will be investigated in joint experiments before embarking on final collaborative studies using draft CRMs to obtain mean yields, repeatability and reproducibility values. Phenolic compounds (phenol, 3 cresol isomers, hydroquinone, catechol and resorcinol gave consistent results by liquid chromatography (LC separation and fluorescence detection after extracting collected “tar” on a Cambridge filter pad (CFP. Yields were similar to those obtained by a derivatisation method followed by gas chromatography - mass spectrometry (GC-MS analysis. Similar ratios of phenols were also obtained from each method. Of the 28 studied analytes, the between-laboratory variability was lowest for the phenols. Hydrogen cyanide was derivatised using various reagents and the colour development measured after continuous flow analysis (CFA by ultra-violet absorbance. Although, methodologies gave reasonably consistent results, investigations on the trapping system

  9. A simple method for optimising transformation of non-parametric data: an illustration by reference to cortisol assays.

    Science.gov (United States)

    Clark, James E; Osborne, Jason W; Gallagher, Peter; Watson, Stuart

    2016-07-01

    Neuroendocrine data are typically positively skewed and rarely conform to the expectations of a Gaussian distribution. This can be a problem when attempting to analyse results within the framework of the general linear model, which relies on assumptions that residuals in the data are normally distributed. One frequently used method for handling violations of this assumption is to transform variables to bring residuals into closer alignment with assumptions (as residuals are not directly manipulated). This is often attempted through ad hoc traditional transformations such as square root, log and inverse. However, Box and Cox (Box & Cox, ) observed that these are all special cases of power transformations and proposed a more flexible method of transformation for researchers to optimise alignment with assumptions. The goal of this paper is to demonstrate the benefits of the infinitely flexible Box-Cox transformation on neuroendocrine data using syntax in spss. When applied to positively skewed data typical of neuroendocrine data, the majority (~2/3) of cases were brought into strict alignment with Gaussian distribution (i.e. a non-significant Shapiro-Wilks test). Those unable to meet this challenge showed substantial improvement in distributional properties. The biggest challenge was distributions with a high ratio of kurtosis to skewness. We discuss how these cases might be handled, and we highlight some of the broader issues associated with transformation. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  10. An analytic-numerical method for the construction of the reference law of operation for a class of mechanical controlled systems

    Science.gov (United States)

    Mizhidon, A. D.; Mizhidon, K. A.

    2017-04-01

    An analytic-numerical method for the construction of a reference law of operation for a class of dynamic systems describing vibrations in controlled mechanical systems is proposed. By the reference law of operation of a system, we mean a law of the system motion that satisfies all the requirements for the quality and design features of the system under permanent external disturbances. As disturbances, we consider polyharmonic functions with known amplitudes and frequencies of the harmonics but unknown initial phases. For constructing the reference law of motion, an auxiliary optimal control problem is solved in which the cost function depends on a weighting coefficient. The choice of the weighting coefficient ensures the design of the reference law. Theoretical foundations of the proposed method are given.

  11. A coupled-enzyme equilibrium method for measuring urea in serum: optimization and evaluation of the AACC study group on urea candidate reference method.

    Science.gov (United States)

    Sampson, E J; Baird, M A; Burtis, C A; Smith, E M; Witte, D L; Bayse, D D

    1980-06-01

    We describe a coupled-enzyme equilibrium method for measuring urea in serum, which is performed on supernates prepared by treating each specimen with Ba(OH)2 and ZnSO4 (Somogyi reagent). Analytical recovery of [14C]urea added to a variety of matrices was essentially complete (mean, 100.6%) for the supernates after precipitation. Nine variables were univariately examined in arriving at the reaction conditions for the method: glutamate dehydrogenase, urease, 2-oxoglutarate, ADP, Tris . HCI, NADH, EDTA, pH, and temperature. The reagent is stable for at least 48 days at--20 degrees C and for 23 days at 4 degrees C. Mean analytical recovery of urea (14 mmol/L) added to seven different specimens (three different matrices) was 100.8%. The analytical linear range of the method extends to 30 mmol of urea per liter. Of 22 potential interferents, only bilirubin at 1 mmol/L (580 mg/L), hemoglobin at 10 g/L, and hydroxyurea at 6 mmol/L showed more than 2% interference. We discuss precision and effects of specimen dilution, and compare results for 100 human serum specimens with those measured for the same specimens with four other urea methods. We examined the effects of measuring a blank, consisting of sample and reagent without urease, with each specimen.

  12. capital. A discussion paper

    Directory of Open Access Journals (Sweden)

    Ewa Chojnacka

    2015-04-01

    Full Text Available The purpose of this study is to confront certain propositions presented in Lesław Niemczyk’s publication Rachunkowość finansowa aktywów kompetencyjnych i kapitału intelektualnego. Nowy dział rachunkowości(Accounting for Competence Assets and Intellectual Capital. A New Area in Accounting with ideas published in other studies. The authors discuss issues concerning firm value, selected definitions of intellectual capital, as well as certain methods of intellectual capital measurement and valuation. Other problems analysed include accounting for and reporting of intellectual capital and similarities and differences between the way those issues are presented in Polish and in international studies as well as in existing legal regulations and standards.

  13. Comparison study for the CCME reference method for determination of PHC in soil by using internal and external standard methods and by using silica gel column cleanup and in-situ silica gel cleanup methods

    International Nuclear Information System (INIS)

    Wang, Z.; Fingas, M.; Sigouin, L.; Yang, C.; Hollebone, B.

    2003-01-01

    The assessment, cleanup, and remediation of hydrocarbon contaminated sites is covered in the Reference Method for Canada-Wide Standard for Petroleum Hydrocarbons-Tier 1 Method. It replaces several analytical methods used in the past by some laboratories and jurisdictions in Canada. The authors conducted two comparative evaluations to validate the Tier 1 Analytical Method. The first compared the Internal and External Standard Methods, and the second compared the Silica Gel Column Cleanup Method with the In-situ Silica Gel Cleanup Method. The Canadian Council of Ministers of the Environment (CCME) Tier 1 Method recommends and requires the External Standard Method to determine petroleum hydrocarbons (PHC) in soil samples. The Internal Method is widely used to quantify various organic and inorganic pollutants in environmental samples. The Tier 1 Method offers two options for the same extract cleanup. They are: Option A - In-situ Silica Gel Cleanup, and Option B - Silica Gel Column Cleanup. Linearity, precision, and PHC quantification results were the parameters considered for diesel and motor oil solutions, for diesel spiked soil samples, and for motor oil spiked soil samples. It was concluded that both the External and Internal Standard Methods for gas chromatograph (GC) determination of PHC in soil possess their own advantages. The PHC results obtained using the In-Situ Silica Gel Cleanup Method were lower than those obtained with the Silica Gel Column Cleanup Methods. The more efficient and effective sample cleanup method proved to be the Silica Gel Column Method. 13 refs., 7 tabs., 7 figs

  14. Serum prolactin revisited: parametric reference intervals and cross platform evaluation of polyethylene glycol precipitation-based methods for discrimination between hyperprolactinemia and macroprolactinemia.

    Science.gov (United States)

    Overgaard, Martin; Pedersen, Susanne Møller

    2017-10-26

    Hyperprolactinemia diagnosis and treatment is often compromised by the presence of biologically inactive and clinically irrelevant higher-molecular-weight complexes of prolactin, macroprolactin. The objective of this study was to evaluate the performance of two macroprolactin screening regimes across commonly used automated immunoassay platforms. Parametric total and monomeric gender-specific reference intervals were determined for six immunoassay methods using female (n=96) and male sera (n=127) from healthy donors. The reference intervals were validated using 27 hyperprolactinemic and macroprolactinemic sera, whose presence of monomeric and macroforms of prolactin were determined using gel filtration chromatography (GFC). Normative data for six prolactin assays included the range of values (2.5th-97.5th percentiles). Validation sera (hyperprolactinemic and macroprolactinemic; n=27) showed higher discordant classification [mean=2.8; 95% confidence interval (CI) 1.2-4.4] for the monomer reference interval method compared to the post-polyethylene glycol (PEG) recovery cutoff method (mean=1.8; 95% CI 0.8-2.8). The two monomer/macroprolactin discrimination methods did not differ significantly (p=0.089). Among macroprolactinemic sera evaluated by both discrimination methods, the Cobas and Architect/Kryptor prolactin assays showed the lowest and the highest number of misclassifications, respectively. Current automated immunoassays for prolactin testing require macroprolactin screening methods based on PEG precipitation in order to discriminate truly from falsely elevated serum prolactin. While the recovery cutoff and monomeric reference interval macroprolactin screening methods demonstrate similar discriminative ability, the latter method also provides the clinician with an easy interpretable monomeric prolactin concentration along with a monomeric reference interval.

  15. Validating fatty acid intake as estimated by an FFQ: how does the 24 h recall perform as reference method compared with the duplicate portion?

    Science.gov (United States)

    Trijsburg, Laura; de Vries, Jeanne Hm; Hollman, Peter Ch; Hulshof, Paul Jm; van 't Veer, Pieter; Boshuizen, Hendriek C; Geelen, Anouk

    2018-05-08

    To compare the performance of the commonly used 24 h recall (24hR) with the more distinct duplicate portion (DP) as reference method for validation of fatty acid intake estimated with an FFQ. Intakes of SFA, MUFA, n-3 fatty acids and linoleic acid (LA) were estimated by chemical analysis of two DP and by on average five 24hR and two FFQ. Plasma n-3 fatty acids and LA were used to objectively compare ranking of individuals based on DP and 24hR. Multivariate measurement error models were used to estimate validity coefficients and attenuation factors for the FFQ with the DP and 24hR as reference methods. Wageningen, the Netherlands. Ninety-two men and 106 women (aged 20-70 years). Validity coefficients for the fatty acid estimates by the FFQ tended to be lower when using the DP as reference method compared with the 24hR. Attenuation factors for the FFQ tended to be slightly higher based on the DP than those based on the 24hR as reference method. Furthermore, when using plasma fatty acids as reference, the DP showed comparable to slightly better ranking of participants according to their intake of n-3 fatty acids (0·33) and n-3:LA (0·34) than the 24hR (0·22 and 0·24, respectively). The 24hR gives only slightly different results compared with the distinctive but less feasible DP, therefore use of the 24hR seems appropriate as the reference method for FFQ validation of fatty acid intake.

  16. Evaluation of the reference unit method for herbaceous biomass estimation in native grasslands of southwestern South Dakota

    Science.gov (United States)

    Eric D. Boyda

    2013-01-01

    The high costs associated with physically harvesting plant biomass may prevent sufficient data collection, which is necessary to account for the natural variability of vegetation at a landscape scale. A biomass estimation technique was previously developed using representative samples or "reference units", which eliminated the need to harvest biomass from all...

  17. A new method to compensate impedance artefacts for Li-ion batteries with integrated micro-reference electrodes

    NARCIS (Netherlands)

    Raijmakers, L.H.J.; Notten, P.H.L.; Lammers, M.J.G.

    2017-01-01

    In order to measure the electrochemical characteristics of both electrodes inside Li-ion batteries, micro-reference electrodes (μREF) turned out to be very useful. However, measuring the electrochemical impedance with respect to μREF can lead to severe measurement artefacts, making a detailed

  18. Growth references

    NARCIS (Netherlands)

    Buuren, S. van

    2007-01-01

    A growth reference describes the variation of an anthropometric measurement within a group of individuals. A reference is a tool for grouping and analyzing data and provides a common basis for comparing populations.1 A well known type of reference is the age-conditional growth diagram. The

  19. Use of reference materials for validating analytical methods. Applied to the determination of As, Co, Na, Hg, Se and Fe using neutron activation analysis

    International Nuclear Information System (INIS)

    Munoz, L; Andonie, O; Kohnenkamp, I

    2000-01-01

    The main purpose of an analytical laboratory is to provide reliable information on the nature and composition of the materials submitted for analysis. This purpose can only be attained if analytical methodologies that have the attributes of accuracy, precision, specificity and sensitivity, among others, are used. The process by which these attributes are evaluated is called validation of the analytical method. The Chilean Nuclear Energy Commission's Neutron Activation Analysis Laboratory is applying a quality guarantee program to ensure the quality of its analytical results, which aims, as well, to attain accreditation for some of its measurements. Validation of the analytical methodologies used is an essential part of applying this program. There are many forms of validation, from comparison with reference techniques to participation in inter-comparison rounds. Certified reference materials were used in this work in order to validate the application of neutron activation analysis in determining As, Co, Na, Hg, Se and Fe in shellfish samples. The use of reference materials was chosen because it is a simple option that easily detects sources of systematic errors. Neutron activation analysis is an instrumental analytical method that does not need chemical treatment and that is based on processes which take place in the nuclei of atoms, making the matrix effects unimportant and different biological reference materials can be used. The following certified reference materials were used for validating the method used: BCR human hair 397, NRCC dogfish muscle DORM-2, NRCC -dogfish liver DOLT-2, NIST - oyster tissue 1566, NIES - mussel 6 and BCR - tuna fish 464. The reference materials were analyzed using the procedure developed for the shellfish samples and the above-mentioned elements were determined. With the results obtained, the parameters of accuracy, precision, detection limit, quantification limit and uncertainty associated with the method were determined for each

  20. A candidate liquid chromatography mass spectrometry reference method for the quantification of the cardiac marker 1-32 B-type natriuretic peptide.

    Science.gov (United States)

    Torma, Attila F; Groves, Kate; Biesenbruch, Sabine; Mussell, Chris; Reid, Alan; Ellison, Steve; Cramer, Rainer; Quaglia, Milena

    2017-08-28

    B-type natriuretic peptide (BNP) is a 32 amino acid cardiac hormone routinely measured by immunoassays to diagnose heart failure. While it is reported that immunoassay results can vary up to 45%, no attempt of standardization and/or harmonization through the development of certified reference materials (CRMs) or reference measurement procedures (RMPs) has yet been carried out. B-type natriuretic peptide primary calibrator was quantified traceably to the International System of Units (SI) by both amino acid analysis and tryptic digestion. A method for the stabilization of BNP in plasma followed by protein precipitation, solid phase extraction (SPE) and liquid chromatography (LC) mass spectrometry (MS) was then developed and validated for the quantification of BNP at clinically relevant concentrations (15-150 fmol/g). The candidate reference method was applied to the quantification of BNP in a number of samples from the UK NEQAS Cardiac Markers Scheme to demonstrate its applicability to generate reference values and to preliminary evaluate the commutability of a potential CRM. The results from the reference method were consistently lower than the immunoassay results and discrepancy between the immunoassays was observed confirming previous data. The application of the liquid chromatography-mass spectrometry (LC-MS) method to the UK NEQAS samples and the correlation of the results with the immunoassay results shows the potential of the method to support external quality assessment schemes, to improve understanding of the bias of the assays and to establish RMPs for BNP measurements. Furthermore, the method has the potential to be multiplexed for monitoring circulating truncated forms of BNP.

  1. The Effect of Matrix Method on Anxiety and Attitude Toward Methamphetamine and Crack Abuse in Males Referring to Addiction Treatment Centers in Tonkabon, Iran

    Directory of Open Access Journals (Sweden)

    Hemmati Sabet

    2015-11-01

    Full Text Available Background Drug abuse is a major problem in the communities and has many harmful effects on human body. Objectives The current study aimed to compare the efficacy of matrix method on anxiety and attitude of male crack abusers referred to addiction treatment centers in Tonkabon, Iran, in 2014. Patients and Methods The current semi -experimental study included 1,000 males referred to addiction treatment centers in Tonkabon with crack abuse history in 2014. Based on Morgan sample volume formula, 278 males with anxiety and higher attitude to drug abuse were randomly selected from 1,000 males referred to addiction treatment centers in Tonkabon. Then, 30 subjects were reselected out of them and equally assigned into two groups of experimental and control, 15 subjects in each group. The experimental group received 24 sessions of 30 - 60 minutes matrix treatment method in group, but the control group received no training. At the end of training period the post-test was carried out. The research findings confirmed the efficacy of matrix method on anxiety and attitude to crack abuse among those referring to the addition treatment center. Results The single covariance analysis of ANCOVA indicated that the value of Eta about 72% of variance of anxiety variable and about 76% of variance of drug abuse variable are taken in to account for variable of group. The intervention was effective in reducing anxiety and attitude to crack in males. Evaluating the adjusted mean showed the effectiveness of matrix method on anxiety and attitude to crack abuse in males. Conclusions The research result showed that matrix method affected the reduction of methamphetamine and attitude to crack abuse in males referred to the addition treatment center.

  2. Enhancing Academic Achievement and Retention in Senior Secondary School Chemistry through Discussion and Lecture Methods: A Case Study of Some Selected Secondary Schools in Gboko, Benue State, Nigeria

    Science.gov (United States)

    Omwirhiren, Efe M.

    2015-01-01

    The present study was initiated to determine how academic achievement and retention in chemistry is enhanced using the two instructional methods among SSII students and ascertained the differential performance of male and female students in chemistry with a view of improving student performance in chemistry. The study adopted a non-equivalent…

  3. Survey of total error of precipitation and homogeneous HDL-cholesterol methods and simultaneous evaluation of lyophilized saccharose-containing candidate reference materials for HDL-cholesterol

    NARCIS (Netherlands)

    C.M. Cobbaert (Christa); H. Baadenhuijsen; L. Zwang (Louwerens); C.W. Weykamp; P.N. Demacker; P.G.H. Mulder (Paul)

    1999-01-01

    textabstractBACKGROUND: Standardization of HDL-cholesterol is needed for risk assessment. We assessed for the first time the accuracy of HDL-cholesterol testing in The Netherlands and evaluated 11 candidate reference materials (CRMs). METHODS: The total error (TE) of

  4. Preparation of an In-House Reference Material Containing Fumonisins in Thai Rice and Matrix Extension of the Analytical Method for Japanese Rice

    Science.gov (United States)

    Awaludin, Norhafniza; Nagata, Reiko; Kawasaki, Tomomi; Kushiro, Masayo

    2009-01-01

    Mycotoxin contamination in rice is less reported, compared to that in wheat or maize, however, some Fusarium fungi occasionally infect rice in the paddy field. Fumonisins are mycotoxins mainly produced by Fusarium verticillioides, which often ruins maize. Rice adherent fungus Gibberella fujikuroi is taxonomically near to F. verticillioides, and there are sporadic reports of fumonisin contamination in rice from Asia, Europe and the United States. Therefore, there exists the potential risk of fumonisin contamination in rice as well as the need for the validated analytical method for fumonisins in rice. Although both natural and spiked reference materials are available for some Fusarium mycotoxins in matrices of wheat and maize, there are no reference materials for Fusarium mycotoxins in rice. In this study, we have developed a method for the preparation of a reference material containing fumonisins in Thai rice. A ShakeMaster grinding machine was used for the preparation of a mixed material of blank Thai rice and F. verticillioides-infected Thai rice. The homogeneity of the mixed material was confirmed by one-way analysis of variance, which led this material to serve as an in-house reference material. Using this reference material, several procedures to extract fumonisins from Thai rice were compared. Accordingly, we proved the applicability of an effective extraction procedure for the determination of fumonisins in Japanese rice. PMID:22069540

  5. Certification of caffeine reference material purity by ultraviolet/visible spectrophotometry and high-performance liquid chromatography with diode-array detection as two independent analytical methods.

    Science.gov (United States)

    Shehata, A B; Rizk, M S; Rend, E A

    2016-10-01

    Caffeine reference material certified for purity is produced worldwide, but no research work on the details of the certification process has been published in the literature. In this paper, we report the scientific details of the preparation and certification of pure caffeine reference materials. Caffeine was prepared by extraction from roasted and ground coffee by dichloromethane after heating in deionized water mixed with magnesium oxide. The extract was purified, dried, and bottled in dark glass vials. Stratified random selection was applied to select a number of vials for homogeneity and stability studies, which revealed that the prepared reference material is homogeneous and sufficiently stable. Quantification of caffeine purity % was carried out using a calibrated UV/visible spectrophotometer and a calibrated high-performance liquid chromatography with diode-array detection method. The results obtained from both methods were combined to drive the certified value and its associated uncertainty. The certified value of the reference material purity was found to be 99.86% and its associated uncertainty was ±0.65%, which makes the candidate reference material a very useful calibrant in food and drug chemical analysis. Copyright © 2016. Published by Elsevier B.V.

  6. Certification of caffeine reference material purity by ultraviolet/visible spectrophotometry and high-performance liquid chromatography with diode-array detection as two independent analytical methods

    Directory of Open Access Journals (Sweden)

    A.B. Shehata

    2016-10-01

    Full Text Available Caffeine reference material certified for purity is produced worldwide, but no research work on the details of the certification process has been published in the literature. In this paper, we report the scientific details of the preparation and certification of pure caffeine reference materials. Caffeine was prepared by extraction from roasted and ground coffee by dichloromethane after heating in deionized water mixed with magnesium oxide. The extract was purified, dried, and bottled in dark glass vials. Stratified random selection was applied to select a number of vials for homogeneity and stability studies, which revealed that the prepared reference material is homogeneous and sufficiently stable. Quantification of caffeine purity % was carried out using a calibrated UV/visible spectrophotometer and a calibrated high-performance liquid chromatography with diode-array detection method. The results obtained from both methods were combined to drive the certified value and its associated uncertainty. The certified value of the reference material purity was found to be 99.86% and its associated uncertainty was ±0.65%, which makes the candidate reference material a very useful calibrant in food and drug chemical analysis.

  7. Comparison between the triglycerides standardization of routine methods used in Japan and the chromotropic acid reference measurement procedure used by the CDC Lipid Standardization Programme.

    Science.gov (United States)

    Nakamura, Masakazu; Iso, Hiroyasu; Kitamura, Akihiko; Imano, Hironori; Noda, Hiroyuki; Kiyama, Masahiko; Sato, Shinichi; Yamagishi, Kazumasa; Nishimura, Kunihiro; Nakai, Michikazu; Vesper, Hubert W; Teramoto, Tamio; Miyamoto, Yoshihiro

    2016-11-01

    Background The US Centers for Disease Control and Prevention ensured adequate performance of the routine triglycerides methods used in Japan by a chromotropic acid reference measurement procedure used by the Centers for Disease Control and Prevention lipid standardization programme as a reference point. We examined standardized data to clarify the performance of routine triglycerides methods. Methods The two routine triglycerides methods were the fluorometric method of Kessler and Lederer and the enzymatic method. The methods were standardized using 495 Centers for Disease Control and Prevention reference pools with 98 different concentrations ranging between 0.37 and 5.15 mmol/L in 141 survey runs. The triglycerides criteria for laboratories which perform triglycerides analyses are used: accuracy, as bias ≤5% from the Centers for Disease Control and Prevention reference value and precision, as measured by CV, ≤5%. Results The correlation of the bias of both methods to the Centers for Disease Control and Prevention reference method was: y (%bias) = 0.516 × (Centers for Disease Control and Prevention reference value) -1.292 ( n = 495, R 2  = 0.018). Triglycerides bias at medical decision points of 1.13, 1.69 and 2.26 mmol/L was -0.71%, -0.42% and -0.13%, respectively. For the combined precision, the equation y (CV) = -0.398 × (triglycerides value) + 1.797 ( n = 495, R 2  = 0.081) was used. Precision was 1.35%, 1.12% and 0.90%, respectively. It was shown that triglycerides measurements at Osaka were stable for 36 years. Conclusions The epidemiologic laboratory in Japan met acceptable accuracy goals for 88.7% of all samples, and met acceptable precision goals for 97.8% of all samples measured through the Centers for Disease Control and Prevention lipid standardization programme and demonstrated stable results for an extended period of time.

  8. Fecal electrolyte testing for evaluation of unexplained diarrhea: Validation of body fluid test accuracy in the absence of a reference method.

    Science.gov (United States)

    Voskoboev, Nikolay V; Cambern, Sarah J; Hanley, Matthew M; Giesen, Callen D; Schilling, Jason J; Jannetto, Paul J; Lieske, John C; Block, Darci R

    2015-11-01

    Validation of tests performed on body fluids other than blood or urine can be challenging due to the lack of a reference method to confirm accuracy. The aim of this study was to evaluate alternate assessments of accuracy that laboratories can rely on to validate body fluid tests in the absence of a reference method using the example of sodium (Na(+)), potassium (K(+)), and magnesium (Mg(2+)) testing in stool fluid. Validations of fecal Na(+), K(+), and Mg(2+) were performed on the Roche cobas 6000 c501 (Roche Diagnostics) using residual stool specimens submitted for clinical testing. Spiked recovery, mixing studies, and serial dilutions were performed and % recovery of each analyte was calculated to assess accuracy. Results were confirmed by comparison to a reference method (ICP-OES, PerkinElmer). Mean recoveries for fecal electrolytes were Na(+) upon spiking=92%, mixing=104%, and dilution=105%; K(+) upon spiking=94%, mixing=96%, and dilution=100%; and Mg(2+) upon spiking=93%, mixing=98%, and dilution=100%. When autoanalyzer results were compared to reference ICP-OES results, Na(+) had a slope=0.94, intercept=4.1, and R(2)=0.99; K(+) had a slope=0.99, intercept=0.7, and R(2)=0.99; and Mg(2+) had a slope=0.91, intercept=-4.6, and R(2)=0.91. Calculated osmotic gap using both methods were highly correlated with slope=0.95, intercept=4.5, and R(2)=0.97. Acid pretreatment increased magnesium recovery from a subset of clinical specimens. A combination of mixing, spiking, and dilution recovery experiments are an acceptable surrogate for assessing accuracy in body fluid validations in the absence of a reference method. Copyright © 2015 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  9. An aggregate method to calibrate the reference point of cumulative prospect theory-based route choice model for urban transit network

    Science.gov (United States)

    Zhang, Yufeng; Long, Man; Luo, Sida; Bao, Yu; Shen, Hanxia

    2015-12-01

    Transit route choice model is the key technology of public transit systems planning and management. Traditional route choice models are mostly based on expected utility theory which has an evident shortcoming that it cannot accurately portray travelers' subjective route choice behavior for their risk preferences are not taken into consideration. Cumulative prospect theory (CPT), a brand new theory, can be used to describe travelers' decision-making process under the condition of uncertainty of transit supply and risk preferences of multi-type travelers. The method to calibrate the reference point, a key parameter to CPT-based transit route choice model, determines the precision of the model to a great extent. In this paper, a new method is put forward to obtain the value of reference point which combines theoretical calculation and field investigation results. Comparing the proposed method with traditional method, it shows that the new method can promote the quality of CPT-based model by improving the accuracy in simulating travelers' route choice behaviors based on transit trip investigation from Nanjing City, China. The proposed method is of great significance to logical transit planning and management, and to some extent makes up the defect that obtaining the reference point is solely based on qualitative analysis.

  10. Learning through Discussions

    Science.gov (United States)

    Ellis, Robert A.; Calvo, Rafael; Levy, David; Tan, Kelvin

    2004-01-01

    Students studying a third-year e-commerce subject experienced face-to-face and online discussions as an important part of their learning experience. The quality of the students' experiences of learning through those discussions is investigated in this study. This study uses qualitative approaches to investigate the variation in the students'…

  11. Application of molecular biological methods in groundwater and drinking water analysis. Papers and discussions; Anwendung molekularbiologischer Verfahren in der Grund- und Trinkwasseranalytik. Textbeitraege und Diskussionsergebnisse

    Energy Technology Data Exchange (ETDEWEB)

    Kuhlmann, B.; Preuss, G. (eds.)

    2000-07-01

    Water management and water supply make demands on microbiology which so far were difficult to meet. However, new molecular-biological methods were developed by ecologically oriented scientists which open up new options in groundwater and freshwater analysis. [German] Aus dem Bereich der Wasserwirtschaft und -versorgung werden vermehrt Anforderungen und Fragen an die Mikrobiologie gestellt, die bisher aufgrund der eingeschraenkten methodischen Moeglichkeiten nur unzureichend beantwortet werden konnten. In unterschiedlichen, meist oekologisch orientierten Forschungsbereichen wurden jedoch neue, im Wesentlichen molekularbiologische Methoden entwickelt, die auch in Hinblick auf die mikrobiologische Untersuchung des Grund- und Trinkwassers neue Perspektiven eroeffneten. (orig.)

  12. Discussion on the environmental protection acceptance method and the critical issues of the completion of projects about radiation usage in the hospitals

    International Nuclear Information System (INIS)

    Wang Wei

    2014-01-01

    It is widely used in the world that the hospitals take advantages of radiation technology. Practically it is involved radioactive isotope, sealed source and the usage of ray device. Based on the environmental protection acceptance of the finished projects, this article is aimed at the actual characteristics of the medical practice and differentiating the major factors of environmental effects, choosing the monitoring criteria and method of environmental protection acceptance and exploring the critical issues in the course of acceptance. Finally this essay is intended to provide theory evidence and technical support in the acceptance of the above projects. (author)

  13. Discussion on resin conversion related problems in the process of using ion exchange method to recover uranium from carbonate lixivium in a uranium mine

    International Nuclear Information System (INIS)

    Yu Suqin; Du Yuhai; Long Qing; Han Wei; Que Weimin

    2012-01-01

    Ion exchange method was used to recover uranium from carbonate lixivium in a uranium mine, lean resin was converted by sodium bicarbonate solution. Because of high sodium bicarbonate, chlorine and uranium concentration in the converted solution, it is difficult to effectively use. Combined with the production practices of the mine, the resin conversion related problems were analyzed. Some measures were taken for improving utilization rate of the converted solution, and good results were obtained. The utilization rate of the converted solution increased to about 20% from less than lO%, and the consumption of sodium bicarbonate reduced by about 30%. (authors)

  14. Establishment of the upper reference limit for thyroid peroxidase autoantibodies according to the guidelines proposed by the National Academy of Clinical Biochemistry: comparison of five different automated methods.

    Science.gov (United States)

    D'Aurizio, Federica; Metus, Paolo; Polizzi Anselmo, Annalisa; Villalta, Danilo; Ferrari, Anna; Castello, Roberto; Giani, Graziella; Tonutti, Elio; Bizzaro, Nicola; Tozzoli, Renato

    2015-12-01

    The estimation of the upper reference limit (URL) for autoantibodies against thyroid peroxidase (TPOAbs) is a controversial issue, because of an uncertainty associated with the criteria used to correctly define the reference population. In addition, the URL of TPOAbs is method-dependent and often arbitrarily established in current laboratory practice. The aim of this study was to determine the reference limits of TPOAbs in a male sample according to the National Academy of Clinical Biochemistry (NACB) guidelines, and to compare them with those obtained in a female group, for five third-generation commercial-automated immunoassay (IMA) platforms. 120 healthy males and 120 healthy females with NACB-required characteristics (younger than 30 years, TSH between 0.5 and 2.0 mIU/L, normal thyroid ultrasound, absence of thyroid disease and absence of other autoimmune diseases) were studied. Sera were analyzed for TPOAbs concentration using five IMA methods applied in automated analyzers: Immulite 2000 XPi (IMM); Maglumi 2000 Plus (MAG); Kryptor Compact Plus (KRY); Phadia 250 (PHA) and Liaison XL (LIA). A statistically significant difference (p reference group for a disease (such as AITD) that affects mainly females. However, in spite of the harmonization among methods provided by the use of an international standard preparation, the wide dispersion of quantitative results still observed in this study suggests the need for further efforts to better understand the cause of these discrepancies, focusing on TPO antigen preparations as the possible source of variability among different assays.

  15. On adequacy of reference sample composition to metal oxide composition in spectral analysis by the method of sublimating additions

    International Nuclear Information System (INIS)

    Zakhariya, N.F.; Turulina, O.P.

    1983-01-01

    The problem on adequacy of zirconium dioxide reference samples to analysed samples is considered. The mechanism of impurities evaporation process in the presence of the sublimating addition for elements of different nature is studied and limiting it stages have been found. It is shown that kinetic probability of impurities transfer into the form of more high-volatile compounds depending on conditions of preparing zirconium dioxide samples may not coincide with the thermodynamic one. With this connected are systematic deviations of the analytical signal value for samples of different technological prehistory

  16. Method of evaluation of diagnostics reference levels in computerized tomography; Metodo de avaliacao de niveis de referencia de radiodiagnostico em tomografia computadorizada

    Energy Technology Data Exchange (ETDEWEB)

    Vega, Walter Flores

    1999-04-01

    Computerized tomography is a complex technique with several selectable exposition parameters delivering high doses to the patient. In this work it was developed a simple methodology to evaluate diagnostic reference levels in computerized tomography, using the concept of Multiple Scan Average Dose (MSAD), recently adopted by the Health Ministry. For evaluation of the MSAD, a dose distribution was obtained through a measured dose profile on the axial axis of a water phantom with thermoluminescence dosemeters, TLD-100, for different exam technique. The MSAD was evaluated hrough two distinct methods. First, it was evaluated by the integration of the dose profile of a single slice and, second, obtained by the integration on central slice of the profile of several slices. The latter is in of accordance with the ionization chamber method, suggesting to be the most practical method of dose evaluation to be applied in the diagnostic reference level assessment routine for CT, using TLDs. (author)

  17. Evaluation of Method-Specific Extraction Variability for the Measurement of Fatty Acids in a Candidate Infant/Adult Nutritional Formula Reference Material.

    Science.gov (United States)

    Place, Benjamin J

    2017-05-01

    To address community needs, the National Institute of Standards and Technology has developed a candidate Standard Reference Material (SRM) for infant/adult nutritional formula based on milk and whey protein concentrates with isolated soy protein called SRM 1869 Infant/Adult Nutritional Formula. One major component of this candidate SRM is the fatty acid content. In this study, multiple extraction techniques were evaluated to quantify the fatty acids in this new material. Extraction methods that were based on lipid extraction followed by transesterification resulted in lower mass fraction values for all fatty acids than the values measured by methods utilizing in situ transesterification followed by fatty acid methyl ester extraction (ISTE). An ISTE method, based on the identified optimal parameters, was used to determine the fatty acid content of the new infant/adult nutritional formula reference material.

  18. #fitspo on Instagram: A mixed-methods approach using Netlytic and photo analysis, uncovering the online discussion and author/image characteristics.

    Science.gov (United States)

    Santarossa, Sara; Coyne, Paige; Lisinski, Carly; Woodruff, Sarah J

    2016-11-01

    The #fitspo 'tag' is a recent trend on Instagram, which is used on posts to motivate others towards a healthy lifestyle through exercise/eating habits. This study used a mixed-methods approach consisting of text and network analysis via the Netlytic program ( N = 10,000 #fitspo posts), and content analysis of #fitspo images ( N = 122) was used to examine author and image characteristics. Results suggest that #fitspo posts may motivate through appearance-mediated themes, as the largest content categories (based on the associated text) were 'feeling good' and 'appearance'. Furthermore, #fitspo posts may create peer influence/support as personal (opposed to non-personal) accounts were associated with higher popularity of images (i.e. number of likes/followers). Finally, most images contained posed individuals with some degree of objectification.

  19. Discussion on the Methods of Heavy Metals Determination in Water Quality Inspection%水质检验中的重金属测定方式探讨

    Institute of Scientific and Technical Information of China (English)

    王霁

    2016-01-01

    The water quality test is closely linked people's life,if the tap water or drinking water contains a lot of heavy metal elements,wil seriously affect human health. Moreover it is lead to anemia and other conditions. At this point,before using the water,it is necessary to purify the water,and to measure the heavy metal in the water quality,so as to provide guarantee for the clean and safe water quality. This article first analyzes the significance of determination of heavy metals ,the biochemical method,atomic absorption spectrometry and electrochemical method was developed for the determination of heavy metals,to provide theoretical support for related research.%水质检验与人们生活紧密联系,若自来水或饮用水中含有诸多重金属元素,会严重影响人体健康,甚至导致贫血等疾病,至此,用水前需对其实施净化处理,测定水质中的重金属,进而为水质的洁净及安全提供保证。本文首先对重金属测定的意义进行分析,探讨生物化学法、原子吸收光谱法及电化学法等测定重金属的方法,以此为相关研究提供理论支撑。

  20. [Reference citation].

    Science.gov (United States)

    Brkić, Silvija

    2013-01-01

    Scientific and professional papers represent the information basis for scientific research and professional work. References important for the paper should be cited within the text, and listed at the end of the paper. This paper deals with different styles of reference citation. Special emphasis was placed on the Vancouver Style for reference citation in biomedical journals established by the International Committee of Medical Journal Editors. It includes original samples for citing various types of articles, both printed and electronic, as well as recommendations related to reference citation in accordance with the methodology and ethics of scientific research and guidelines for preparing manuscripts for publication.

  1. A comparison of the suitability of patient dosimetry methods for establishing diagnostic dose reference levels and optimisation strategies

    International Nuclear Information System (INIS)

    Gfirtner, Hans; Moores, B. Michael; Stieve, Friedrich E.

    2008-01-01

    For 50 adult patients referred for chest radiography, air kerma at the diaphragm KD, dose area product and entrance skin dose were measured. The air kerma at the diaphragm and the dose area product were determined using Diamentor M4KDK(PTW) which allows measuring air kerma and dose area product simultaneously. For the measurement of entrance skin dose TLDs are used. A 50% variation in dose, incident dose as well as entrance skin dose, was registered for the same patient thickness. The recommendation of ICRP to perform the measurements for DRLs at 'representative patients' and that of the CEC to use 'standard-sized patients' seem to make little sense in the case of chest radiography. It could be demonstrated, that the dose area product is the least appropriate dose quantity for patient measurements and to define dose reference levels. For some radiological examinations like chest, pelvis and lumbar spine the dose area product is even sex dependent. Incident dose and entrance surface dose are of equal quality for patient dose measurements in diagnostic radiography. (author)

  2. Factors influencing superimposition error of 3D cephalometric landmarks by plane orientation method using 4 reference points: 4 point superimposition error regression model.

    Science.gov (United States)

    Hwang, Jae Joon; Kim, Kee-Deog; Park, Hyok; Park, Chang Seo; Jeong, Ho-Gul

    2014-01-01

    Superimposition has been used as a method to evaluate the changes of orthodontic or orthopedic treatment in the dental field. With the introduction of cone beam CT (CBCT), evaluating 3 dimensional changes after treatment became possible by superimposition. 4 point plane orientation is one of the simplest ways to achieve superimposition of 3 dimensional images. To find factors influencing superimposition error of cephalometric landmarks by 4 point plane orientation method and to evaluate the reproducibility of cephalometric landmarks for analyzing superimposition error, 20 patients were analyzed who had normal skeletal and occlusal relationship and took CBCT for diagnosis of temporomandibular disorder. The nasion, sella turcica, basion and midpoint between the left and the right most posterior point of the lesser wing of sphenoidal bone were used to define a three-dimensional (3D) anatomical reference co-ordinate system. Another 15 reference cephalometric points were also determined three times in the same image. Reorientation error of each landmark could be explained substantially (23%) by linear regression model, which consists of 3 factors describing position of each landmark towards reference axes and locating error. 4 point plane orientation system may produce an amount of reorientation error that may vary according to the perpendicular distance between the landmark and the x-axis; the reorientation error also increases as the locating error and shift of reference axes viewed from each landmark increases. Therefore, in order to reduce the reorientation error, accuracy of all landmarks including the reference points is important. Construction of the regression model using reference points of greater precision is required for the clinical application of this model.

  3. Session 1 - discussion

    International Nuclear Information System (INIS)

    Wells, C.; Richards, K.M.; McKerrow, J.F.

    1991-01-01

    This discussion session of the Landfill Gas-Energy and Environment 90 Conference covered the landfill gas potential, the setting up of the Non-Fossil Fuel Obligation; anticipated developments in the post 1998 period, the problem of smell for those who live near a landfill, and the length of time a landfill site is productive in terms of gas evolution. Relevant regulations in California are briefly discussed. (author)

  4. Reference values assessment in a Mediterranean population for small dense low-density lipoprotein concentration isolated by an optimized precipitation method

    Directory of Open Access Journals (Sweden)

    Fernández-Cidón B

    2017-06-01

    Full Text Available Bárbara Fernández-Cidón,1–3 Ariadna Padró-Miquel,1 Pedro Alía-Ramos,1 María José Castro-Castro,1 Marta Fanlo-Maresma,4 Dolors Dot-Bach,1 José Valero-Politi,1 Xavier Pintó-Sala,4 Beatriz Candás-Estébanez1 1Clinical Laboratory, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Spain; 2Department of Biochemistry, Molecular Biology and Biomedicine, Autonomous University of Barcelona (UAB, Barcelona, Spain; 3Department of Pharmacotherapy, Pharmacogenetics and Pharmaceutical Technology, Institut d’Investigació Biomèdica de Bellvitge (IDIBELL, L’Hospitalet de Llobregat, Spain; 4Cardiovascular Risk Unit, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Spain Background: High serum concentrations of small dense low-density lipoprotein cholesterol (sd-LDL-c particles are associated with risk of cardiovascular disease (CVD. Their clinical application has been hindered as a consequence of the laborious current method used for their quantification. Objective: Optimize a simple and fast precipitation method to isolate sd-LDL particles and establish a reference interval in a Mediterranean population. Materials and methods: Forty-five serum samples were collected, and sd-LDL particles were isolated using a modified heparin-Mg2+ precipitation method. sd-LDL-c concentration was calculated by subtracting high-density lipoprotein cholesterol (HDL-c from the total cholesterol measured in the supernatant. This method was compared with the reference method (ultracentrifugation. Reference values were estimated according to the Clinical and Laboratory Standards Institute and The International Federation of Clinical Chemistry and Laboratory Medicine recommendations. sd-LDL-c concentration was measured in serums from 79 subjects with no lipid metabolism abnormalities. Results: The Passing–Bablok regression equation is y = 1.52 (0.72 to 1.73 + 0.07x (−0.1 to 0.13, demonstrating no significant statistical differences

  5. Discussion about decision support systems using continuous multi-criteria methods for planning in areas with hydro-basins, agriculture and forests, from examples in Argentine.

    Science.gov (United States)

    Anton, J. M.; Grau, J. B.; Tarquis, A. M.; Andina, D.; Cisneros, J. M.; Sanchez, E.

    2012-04-01

    The authors were involved last years in projects considering diverse decision problems on the use of some regions in Argentine, and also related to rivers or rural services in them. They used sets of multi-criteria decision methods, first discrete when the problem included few distinct alternatives, such as e.g. forestry, traditional or intensive agriculture. For attributes they were different effects, classified then in environmental, economic and social criteria. Extending to other gentler areas, such as at South of the Province of Córdoba, Arg., they have balanced more delicately effects of continuous levels of actions, with a combination of Goal Programming linked methods, and they adopted compromises to have precise solutions. That has shown, and in part open, a line of research, as the setting of such models require various kinds of definitions and valuations, including optimizations, goals with penalties in deviations and restrictions. That can be in diverse detail level and horizon, in presence of various technical and human horizons, and that can influence politics of use of terrain and production that will require public and private agents. The research will consider consideration of use and conservation of soils, human systems and agro productions, and hence models for optimization, preferably in such Goal Programming ways. That will require considering various systems of models, first in theory to be reliable, and then in different areas to evaluate the quality of conclusions, and maybe that successively if results are found advantageous. The Bayesian ways will be considered, but they would require a prospective of sets of precise future states of nature or markets with elicited probabilities, which are neither evident nor decisive for the moment, as changes may occur in years but will be very unexpected or uncertain. The results will be lines of models to aid to establish policies of use of territories, by public agencies setting frames for private

  6. Analysis of the Possibilities for Discussing Questions of Global Justice in Geography Classes on the Use of Methods of Empirical Social Research When Analyzing the Teaching of Geography in Class

    Science.gov (United States)

    Applis, Stefan

    2015-01-01

    This study examines students' orientations with regard to questions on the implementation of justice in production structures of the global textile industry. The students worked with the Mystery Method from the Thinking Through Geography approach by David Leat and with Lawrence Kohlberg's Method of Dilemma Discussion. During this process, the…

  7. Reference Tracking and Profit Optimization of a Power Plant

    DEFF Research Database (Denmark)

    Kragelund, Martin Nygaard; Leth, John-Josef; Wisniewski, Rafal

    2010-01-01

    In this paper we discuss two different methods for implementing reference tracking intro a profit optimization problem of a power plant. It is shown that tracking included as a side constraint results in an significant tracking error only when the reference gradient is large. When tracking...... is included in the cost function, as a quadratic term, the reference is tracked with a small accumulated error. Finally, the two methods are compared both in terms of tracking performance and computational burden....

  8. Determination of rare earth and uranium in reference biological materials certified by the method of neutron activation analysis

    International Nuclear Information System (INIS)

    Pereira, Lais H.P.; Saiki, Mitiko

    2013-01-01

    The objective of this study was to evaluate the precision and accuracy of the determinations of Sc, La, Ce, Nd, Sm, Eu, Tb, Yb, Lu and U in certified reference materials (CRMs). To solve the problem of interference from fission products of U in the determination of lanthanides were obtained correction factors for this interference for 140 La, 141 Ce, 143 Ce, 153 Sm and 147 Nd. The experimental procedure of Neutron Activation Analysis consisted of irradiating aliquots of each of the CRMs with synthetic standards of elements under thermal neutron flux of the IEA-R1 nuclear reactor, followed by gamma-ray spectrometry using a high-resolution hyperpurity GE detector. The analyzes of CRMs indicate good accuracy and precision of results, demonstrating the feasibility of applying of established procedure in NAA of elements studied in organic vegetable matrices

  9. Impact of age, sex, and indexation method on MR left ventricular reference values in the Framingham Heart Study offspring cohort.

    Science.gov (United States)

    Yeon, Susan B; Salton, Carol J; Gona, Philimon; Chuang, Michael L; Blease, Susan J; Han, Yuchi; Tsao, Connie W; Danias, Peter G; Levy, Daniel; O'Donnell, Christopher J; Manning, Warren J

    2015-04-01

    To determine normative values for left ventricular (LV) volumes, mass, concentricity, and ejection fraction (EF) and investigate associations between sex, age, and body size with LV parameters in community-dwelling adults. In all, 1794 Framingham Heart Study Offspring cohort members underwent LV short-axis oriented, contiguous multislice cine steady-state free precession MR of the left ventricle; from these a healthy referent group (n = 852, 61 ± 9 years, 40% men) free of clinical cardiac disease and hypertension (SBP 65 years); LV parameters were indexed to measures of body size. Men have greater LV volumes and mass than women both before and after indexation to height, powers of height, and body surface area (P J. Magn. Reson. Imaging 2015;41:1038-1045. © 2014 Wiley Periodicals, Inc. © 2014 Wiley Periodicals, Inc.

  10. Reference Assessment

    Science.gov (United States)

    Bivens-Tatum, Wayne

    2006-01-01

    This article presents interesting articles that explore several different areas of reference assessment, including practical case studies and theoretical articles that address a range of issues such as librarian behavior, patron satisfaction, virtual reference, or evaluation design. They include: (1) "Evaluating the Quality of a Chat Service"…

  11. Japanese Society for Laboratory Hematology flow cytometric reference method of determining the differential leukocyte count: external quality assurance using fresh blood samples.

    Science.gov (United States)

    Kawai, Y; Nagai, Y; Ogawa, E; Kondo, H

    2017-04-01

    To provide target values for the manufacturers' survey of the Japanese Society for Laboratory Hematology (JSLH), accurate standard data from healthy volunteers were needed for the five-part differential leukocyte count. To obtain such data, JSLH required an antibody panel that achieved high specificity (particularly for mononuclear cells) using simple gating procedures. We developed a flow cytometric method for determining the differential leukocyte count (JSLH-Diff) and validated it by comparison with the flow cytometric differential leukocyte count of the International Council for Standardization in Haematology (ICSH-Diff) and the manual differential count obtained by microscopy (Manual-Diff). First, the reference laboratory performed an imprecision study of JSLH-Diff and ICSH-Diff, as well as performing comparison among JSLH-Diff, Manual-Diff, and ICSH-Diff. Then two reference laboratories and seven participating laboratories performed imprecision and accuracy studies of JSLH-Diff, Manual-Diff, and ICSH-Diff. Simultaneously, six manufacturers' laboratories provided their own representative values by using automated hematology analyzers. The precision of both JSLH-Diff and ICSH-Diff methods was adequate. Comparison by the reference laboratory showed that all correlation coefficients, slopes and intercepts obtained by the JSLH-Diff, ICSH-Diff, and Manual-Diff methods conformed to the criteria. When the imprecision and accuracy of JSLH-Diff were assessed at seven laboratories, the CV% for lymphocytes, neutrophils, monocytes, eosinophils, and basophils was 0.5~0.9%, 0.3~0.7%, 1.7~2.6%, 3.0~7.9%, and 3.8~10.4%, respectively. More than 99% of CD45 positive leukocytes were identified as normal leukocytes by JSLH-Diff. When JSLH-Diff method were validated by comparison with Manual-Diff and ICSH-Diff, JSLH-Diff showed good performance as a reference method. © 2016 John Wiley & Sons Ltd.

  12. Production of Landsat ETM+ reference imagery of burned areas within Southern African savannahs: comparison of methods and application to MODIS

    Science.gov (United States)

    A. M. S. Smith; N. A. Drake; M. J. Wooster; A. T. Hudak; Z. A. Holden; C. J. Gibbons

    2007-01-01

    Accurate production of regional burned area maps are necessary to reduce uncertainty in emission estimates from African savannah fires. Numerous methods have been developed that map burned and unburned surfaces. These methods are typically applied to coarse spatial resolution (1 km) data to produce regional estimates of the area burned, while higher spatial resolution...

  13. Discussion on Papers 14 - 16

    International Nuclear Information System (INIS)

    Charles-Jones, S.; Muirhead, S.; Wilson, E.A.; Jefferson, M.; Binnie, C.J.A.; O'Connor, B.A.; Rothwell, P.; Cowie, D.

    1992-01-01

    Further observations were made on the great potential for tidal power developments in NW Australia. Discussion on the Severn Barrage paper and environmental effects of tidal power plants centred mainly around the impact on bird populations. The topics covered were: the adaptability of birds to changes in their environment with particular reference to the importance of inter-tidal areas for wildfowl and wading birds in the United Kingdom; the creation of mudflats as replacement feeding areas for wading birds; whether there is a danger that pressure from the construction industry might result in a barrage being built before the uncertainties in the environmental impact assessment are removed. Separate abstracts have been prepared for the three papers under discussion. (UK)

  14. Summary of group discussions

    International Nuclear Information System (INIS)

    2009-01-01

    A key aspect of the workshop was the interaction and exchange of ideas and information among the 40 participants. To facilitate this activity the workshop participants were divided into five discussions groups. These groups reviewed selected subjects and reported back to the main body with summaries of their considerations. Over the 3 days the 5 discussion groups were requested to focus on the following subjects: the characteristics and capabilities of 'good' organisations; how to ensure sufficient resources; how to ensure competence within the organisation; how to demonstrate organisational suitability; the regulatory oversight processes - including their strengths and weaknesses. A list of the related questions that were provided to the discussion groups can be found in Appendix 3. Also included in Appendix 3 are copies of the slides the groups prepared that summarised their considerations

  15. Focus group discussions

    CERN Document Server

    Hennink, Monique M

    2014-01-01

    The Understanding Research series focuses on the process of writing up social research. The series is broken down into three categories: Understanding Statistics, Understanding Measurement, and Understanding Qualitative Research. The books provide researchers with guides to understanding, writing, and evaluating social research. Each volume demonstrates how research should be represented, including how to write up the methodology as well as the research findings. Each volume also reviews how to appropriately evaluate published research. Focus Group Discussions addresses the challenges associated with conducting and writing focus group research. It provides detailed guidance on the practical and theoretical considerations in conducting focus group discussions including: designing the discussion guide, recruiting participants, training a field team, moderating techniques and ethical considerations. Monique Hennink describes how a methodology section is read and evaluated by others, such as journal reviewers or ...

  16. Plutonium roundtable discussion

    International Nuclear Information System (INIS)

    Penneman, R.A.

    1982-01-01

    The roundtable discussion began with remarks by the chairman who pointed out the complicated nature of plutonium chemistry. Judging from the papers presented at this symposium, he noticed a pattern which indicated to him the result of diminished funding for investigation of basic plutonium chemistry and funding focused on certain problem areas. Dr. G.L. silver pointed to plutonium chemists' erroneous use of a simplified summary equation involving the disproportionation of Pu(EV) and their each of appreciation of alpha coefficients. To his appreciation of alpha coefficients. To his charges, Dr. J.T. Bell spoke in defense of the chemists. This discussion was followed by W.W. Schulz's comments on the need for experimental work to determine solubility data for plutonium in its various oxidation states under geologic repository conditions. Discussion then turned to plutonium pyrachemical process with Dana C. Christensen as the main speaker. This paper presents edited versions of participants' written version

  17. Development of a reference material for routine performance monitoring of methods measuring polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and dioxin-like polychlorinated biphenyls.

    Science.gov (United States)

    Selliah, S S; Cussion, S; MacPherson, K A; Reiner, E J; Toner, D

    2001-06-01

    Matrix-matched environmental certified reference materials (CRMs) are one of the most useful tools to validate analytical methods, assess analytical laboratory performance and to assist in the resolution of data conflicts between laboratories. This paper describes the development of a lake sediment as a CRM for polychorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and dioxin-like polychlorinated biphenyls (DLPCBs). The presence of DLPCBs in the environment is of increased concern and analytical methods are being developed internationally for monitoring DLPCBs in the environment. This paper also reports the results of an international interlaboratory study involving thirty-five laboratories from seventeen countries, conducted to characterize and validate levels of a sediment reference material for PCDDs, PCDFs and DLPCBs.

  18. Contribution of nuclear analysis methods to the certification of BCR reference materials for non-metals in non-ferrous metals

    International Nuclear Information System (INIS)

    Pauwels, J.

    1979-01-01

    A number of reference materials for oxygen in different non-ferrous metals have been certified by BCR in the frame of a multidisciplinary Community project. The contribution of nuclear analysis methods is illustrated by several examples concerning the optimization of sample preparation techniques, the analysis of low and high oxygen non-ferrous metals and the extension of the program to other non-metals, especially nitrogen and carbon. (author)

  19. Definition of the upper reference limit for thyroglobulin antibodies according to the National Academy of Clinical Biochemistry guidelines: comparison of eleven different automated methods

    OpenAIRE

    D?Aurizio, F.; Metus, P.; Ferrari, A.; Caruso, B.; Castello, R.; Villalta, D.; Steffan, A.; Gaspardo, K.; Pesente, F.; Bizzaro, N.; Tonutti, E.; Valverde, S.; Cosma, C.; Plebani, M.; Tozzoli, R.

    2017-01-01

    Purpose In the last two decades, thyroglobulin autoantibodies (TgAb) measurement has progressively switched from marker of thyroid autoimmunity to test associated with thyroglobulin (Tg) to verify the presence or absence of TgAb interference in the follow-up of patients with differentiated thyroid cancer. Of note, TgAb measurement is cumbersome: despite standardization against the International Reference Preparation MRC 65/93, several studies demonstrated high inter-method variability and wid...

  20. Preparation of the new certified reference material Virginia Tobacco Leaves (CTA-VTL-2) and development of suitable methods for checking the homogeneity

    International Nuclear Information System (INIS)

    Dybczynski, R.; Polkowska-Motrenko, H.; Samczynski, Z.; Szopa, Z.

    1994-01-01

    The aim of this project in the long run has been reparation of a new biological reference material: Tobacco leaves of the 'Virginia' type and its certification for the content of possibly great number of trace elements. Further aims have been: development of the suitable methods for checking the homogeneity with the special emphasis on homogeneity of small samples and the critical analysis of the performance of various analytical techniques

  1. Discussion on nuclear issues

    International Nuclear Information System (INIS)

    Andrlova, Z.

    2012-01-01

    Treatment of the radioactive waste and utilisation of the ionisation radiation. Interesting contributions to two topics appeared in conference of Slovak Nuclear Society in Casta-Papiernicka in May 2012. The members from the female section 'Women in nuclear sector; were discussing in particular of the mind-set of Europeans to radioactive waste and novelties in nuclear medicine. (author)

  2. Summary of discussion

    International Nuclear Information System (INIS)

    2006-01-01

    This document provides summaries of the discussions occurred during the second international workshop on the indemnification of nuclear damage. It concerns the second accident scenario: a fire on board of a ship transporting enriched uranium hexafluoride along the Danube River. (A.L.B.)

  3. Discussion 2: David Dobbs

    OpenAIRE

    Dobbs, David; Murray-Rust, Peter; Hatcher, Jordan; Pollock, Rufus

    2010-01-01

    David Dobbs writes on science, medicine and culture. He has contributed to a diversity of publications, including Scientific American, Slate magazine, Wired, Audubon, Atlantic Monthly, and the New York Times magazine. He has also authored a number of books. Other participants in this discussion were Peter Murray-Rust, Jordan Hatcher, and Rufus Pollock.

  4. Summary and Discussion.

    Science.gov (United States)

    Hetherington, E. Mavis

    1992-01-01

    Summarizes and discusses results of the longitudinal study that comprises this monograph issue. Results concern: (1) marital, parent-child, and sibling relationships in families with single and remarried mothers; (2) the relationship between parenting style and adolescent adjustment; and (3) the relationship between marital transitions and…

  5. WORKSHOP: Discussion, debate, deliberation

    NARCIS (Netherlands)

    Jeliazkova, Margarita I.

    2014-01-01

    Discussing, deliberating and debating are a core part of any democratic process. To organise these processes well, a great deal of knowledge and skill is required. It is not simple to find a good balance between a number of elements: appropriate language and terminology; paying attention to solid

  6. Recent references

    International Nuclear Information System (INIS)

    Ramavataram, S.

    1991-01-01

    In support of a continuing program of systematic evaluation of nuclear structure data, the National Nuclear Data Center maintains a complete computer file of references to the nuclear physics literature. Each reference is tagged by a keyword string, which indicates the kinds of data contained in the article. This master file of Nuclear Structure References (NSR) contains complete keyword indexes to literature published since 1969, with partial indexing of older references. Any reader who finds errors in the keyword descriptions is urged to report them to the National Nuclear Data Center so that the master NSR file can be corrected. In 1966, the first collection of Recent References was published as a separate issue of Nuclear Data Sheets. Every four months since 1970, a similar indexed bibliography to new nuclear experiments has been prepared from additions to the NSR file and published. Beginning in 1978, Recent References was cumulated annually, with the third issue completely superseding the two issues previously published during a given year. Due to publication policy changes, cumulation of Recent Reference was discontinued in 1986. The volume and issue number of all the cumulative issues published to date are given. NNDC will continue to respond to individual requests for special bibliographies on nuclear physics topics, in addition to those easily obtained from Recent References. If the required information is available from the keyword string, a reference list can be prepared automatically from the computer files. This service can be provided on request, in exchange for the timely communication of new nuclear physics results (e.g., preprints). A current copy of the NSR file may also be obtained in a standard format on magnetic tape from NNDC. Requests for special searches of the NSR file may also be directed to the National Nuclear Data Center

  7. Calculations of non-adiabatic couplings within equation-of-motion coupled-cluster framework: Theory, implementation, and validation against multi-reference methods

    Science.gov (United States)

    Faraji, Shirin; Matsika, Spiridoula; Krylov, Anna I.

    2018-01-01

    We report an implementation of non-adiabatic coupling (NAC) forces within the equation-of-motion coupled-cluster with single and double excitations (EOM-CCSD) framework via the summed-state approach. Using illustrative examples, we compare NAC forces computed with EOM-CCSD and multi-reference (MR) wave functions (for selected cases, we also consider configuration interaction singles). In addition to the magnitude of the NAC vectors, we analyze their direction, which is important for the calculations of the rate of non-adiabatic transitions. Our benchmark set comprises three doublet radical-cations (hexatriene, cyclohexadiene, and uracil), neutral uracil, and sodium-doped ammonia clusters. When the characters of the states agree among different methods, we observe good agreement between the respective NAC vectors, both in the Franck-Condon region and away. In the cases of large discrepancies between the methods, the disagreement can be attributed to the difference in the states' character, which, in some cases, is very sensitive to electron correlation, both within single-reference and multi-reference frameworks. The numeric results confirm that the accuracy of NAC vectors depends critically on the quality of the underlying wave functions. Within their domain of applicability, EOM-CC methods provide a viable alternative to MR approaches.

  8. Evaluation of the PREVI® Isola automated seeder system compared to reference manual inoculation for antibiotic susceptibility testing by the disk diffusion method.

    Science.gov (United States)

    Le Page, S; van Belkum, A; Fulchiron, C; Huguet, R; Raoult, D; Rolain, J-M

    2015-09-01

    The disk diffusion (DD) method remains the most popular manual technique for antibiotic susceptibility testing (AST) in clinical microbiology laboratories. This is because of its simplicity, reproducibility, and limited cost compared to (automated) microdilution systems, which are usually less sensitive at detecting certain important mechanisms of resistance. Here, we evaluate the PREVI® Isola automated seeder system using a new protocol for spreading bacterial suspensions (eight deposits of calibrated inocula of bacteria, followed by two rounds of rotation) in comparison with manual DD reference testing on a large series of clinical and reference strains. The average time required for seeding one agar plate for DD with this new protocol was 51 s per plate, i.e., 70 agar plates/h. Reproducibility and repeatability was assessed on three reference and three randomly chosen clinical strains, as usually requested by the European Committee on Antimicrobial Susceptibility Testing (EUCAST), and was excellent compared to the manual method. The standard deviations of zones of growth inhibition showed no statistical discrimination. The correlation between the two methods, assessed using 294 clinical isolates and a panel of six antibiotics (n = 3,528 zones of growth inhibition measured), was excellent, with a correlation coefficient of 0.977. The new PREVI® Isola protocol adapted for DD had a sensitivity of 99 % and a specificity of 100 % compared to the manual technique for interpreting DD as recommended by the EUCAST.

  9. The calculation of dose from photon exposures using reference human phantoms and Monte Carlo methods. Pt. 5

    International Nuclear Information System (INIS)

    Petoussi, N.; Zankl, M.; Williams, G.; Veit, R.; Drexler, G.

    1987-01-01

    There has been some evidence that cervical cancer patients who were treated by radiotherapy, had an increased incidence of second primary cancers noticeable 15 years or more after the radiotherapy. The data suggested that high dose pelvic irradiation was associated with increase in cancers of the bladder, kidneys, rectum, ovaries, corpus uteri, and non-Hodgkin's lymphoma but not leukemia (Kleinerman et al., 1982, Morton 1973). The aim of the present work is to estimate the absorbed dose, due to radiotherapy treatment for cervival cancer, to various organs and tissues in the body. Monte Carlo calculations were performed to calculate the organ absorbed doses resulting from intracavitary sources such as ovoids and applicators filled or loaded with radium, Co-60 and Cs-137. For that purpose a routine which simulates an internal source was constructed and added to the existing Monte Carlo code (GSF-Bericht S-885, Kramer et al.). Calculations were also made for external beam therapy. Various anterior, posterior and lateral fields were applied, resulting from megavoltage, Co-60 and Cs-137 therapy machines. The calculated organ doses are tabulated in three different ways: as organ dose per air Kerma in the reference field, according to the recommendations of the International Commission on Radiation Units and Measurements (ICRU Report No 38, 1985); as organ dose per surface dose and as organ dose per tissue dose at Point B. (orig.)

  10. Panel discussion : contract design

    Energy Technology Data Exchange (ETDEWEB)

    Vallas, A. [Sempra Energy Trading, Toronto, ON (Canada); Vegh, G. [MacLeod Dixon, Toronto, ON (Canada); McGee, M. [Energy Profiles Ltd., Etobicoke, ON (Canada); Zaremba, T. [Direct Energy Marketing, Calgary, AB (Canada); Seshan, A. [Larson and Toubro Information Technology, Toronto, ON (Canada); Harricks, P. [Gowlings, Toronto, ON (Canada); Bertoldi, L. [Borden Ladner Gervais, Toronto, ON (Canada); Taylor, R. [Hydro One Networks Inc., Markham, ON (Canada)

    2003-05-01

    This session presented highlights of the comments of 8 panelists who discussed the issue of contract design. The new electricity market in Ontario has introduced the energy trader, who enters into a contract with the consumer, based on the spot price set by the Independent Electricity Market Operator. Every contract has a fixed price payer as well as floating-price payers. If the floating price for a given amount of energy is higher than the fixed price, then the consumer gets the difference. Confusion, however, arises with the purchase of retail physical power in the market, particularly in deciding a fixed rate that the consumer will be paying. Different billing options were also discussed with emphasis on mid to large retail customers that have portfolios in the tens of MW and up to 100 MW or more. figs.

  11. Panel discussion : contract design

    International Nuclear Information System (INIS)

    Vallas, A.; Vegh, G.; McGee, M.; Zaremba, T.; Seshan, A.; Harricks, P.; Bertoldi, L.; Taylor, R.

    2003-01-01

    This session presented highlights of the comments of 8 panelists who discussed the issue of contract design. The new electricity market in Ontario has introduced the energy trader, who enters into a contract with the consumer, based on the spot price set by the Independent Electricity Market Operator. Every contract has a fixed price payer as well as floating-price payers. If the floating price for a given amount of energy is higher than the fixed price, then the consumer gets the difference. Confusion, however, arises with the purchase of retail physical power in the market, particularly in deciding a fixed rate that the consumer will be paying. Different billing options were also discussed with emphasis on mid to large retail customers that have portfolios in the tens of MW and up to 100 MW or more. figs

  12. Discussion with CERN Directorate

    CERN Document Server

    CERN. Geneva

    2017-01-01

    Please note that the Discussion with CERN Directorate will be transmitted also in the following rooms: Council Chamber - 503-1-001 IT Amphitheatre - 31-3-004 Prevessin 774-R-013 Simultaneous interpreting into French and English will be available in the Main Auditorium. Une interprétation simultanée en français et en anglais sera disponible dans l'amphithéâtre principal.

  13. Evaluation of the k0 method by its application to (n, γ)RNaa of geological, environmental and clay reference materials

    International Nuclear Information System (INIS)

    Corte, F. de; Lin Xilei; Moens, L.; Wispelaere, A. de; Hoste, J.; Demeter, A.; Simonits, A.

    1984-01-01

    The k 0 standardization method, the state-of-the-art of which is shortly reviewed, has been applied to multi-element reactor neutron activation analysis of (standard) reference materials. The analyses have been performed independently at the Institute for Nuclear Sciences (Gent, Belgium) and the Central Research Institute for Physics (Budapest, Hungary). Results are given for USGS-2 (granite), NBS SRM-1633a (coal fly ash) and FCG (fired clay of Gent). Comparison with literature data shows that the k 0 method, while being experimentally simple, versatile and suited for computerization, offers a potential accuracy of better than 5%. (author)

  14. Why do women not return family history forms when referred to breast cancer genetics services? A mixed-method study.

    Science.gov (United States)

    Hanning, Kirstie A; Steel, Michael; Goudie, David; McLeish, Lorna; Dunlop, Jackie; Myring, Jessica; Sullivan, Frank; Berg, Jonathan; Humphris, Gerry; Ozakinci, Gozde

    2015-10-01

    Personal and family data forms, completed by women referred to breast cancer genetics clinics, are valuable tools for verification and extension of family history, crucial steps in accurate risk evaluation. A significant minority of women do not complete and return these forms, despite reminders, even when completion is a pre-requisite for a clinic appointment. To facilitate access of women at increased familial risk of breast cancer to screening and counselling services by investigating reasons for non-return of the forms. Based on a single regional 'breast cancer family' service in the UK, Analysis of quantitative data comparing women who did not return forms (n = 55) with those who had done so (n = 59), together with qualitative evaluation of potential barriers to form-completion through semi-structured telephone interviews with a random subset of 'non-returners' (n = 23). Non-returners have higher proportions of the very young (below the age at which surveillance could be offered) and of women from lower social deprivation categories. Interviews revealed that the majority of non-returners are anxious, rather than unconcerned about their breast cancer risk and circumstances and attitudes contributed to non-compliance. Twenty-one participants confirmed that they would welcome an appointment at a 'breast cancer family' clinic, but nine did not attend for the appointment. They were significantly younger than those who attend, but were not at lower familial risk. Many women who fail to complete and return a family history form would benefit from risk assessment and genetic counselling. Several steps are suggested that might help them access the relevant services. © 2014 John Wiley & Sons Ltd.

  15. A regional benthic fauna assessment method for the Southern North Sea using Margalef diversity and reference value modelling

    NARCIS (Netherlands)

    Loon, van Willem M.G.M.; Walvoort, Dennis J.J.; Hoey, van Gert; Vina-Herbon, Christina; Blandon, Abigayil; Pesch, Roland; Schmitt, Petra; Scholle, Jörg; Heyer, Karin; Lavaleye, Marc; Phillips, Graham; Duineveld, Gerard C.A.; Blomqvist, Mats

    2018-01-01

    The aims of this study are to develop an optimized method for regional benthic fauna assessment of the Southern North Sea which (a) is sensitive and precise (quantified as the slope and the R2 value of the pressure-impact relationships, respectively) for the anthropogenic pressures bottom fishing

  16. Purity Assessment of Organic Reference Materials with a Mass Balance Method: A Case Study of Endosulfan-II

    International Nuclear Information System (INIS)

    Kim, Seunghyun; Lee, Joonhee; Ahn, Seonghee; Song, Youngsin; Kim, Dongkyun; Kim, Byungjoo

    2013-01-01

    A mass balance method established in this laboratory was applied to determine the purity of an endosulfan-II pure substance. Gas chromatography-flame ionization detector (GC-FID) was used to measure organic impurities. Total of 10 structurally related organic impurities were detected by GC-FID in the material. Water content was determined to be 0.187% by Karl-Fischer (K-F) coulometry with an oven-drying method. Nonvolatile residual impurities was not detected by Thermal gravimetric analysis (TGA) within the detection limit of 0.04% (0.7 μg in absolute amount). Residual solvents within the substance were determined to be 0.007% in the Endosulfan-II pure substance by running GC-FID after dissolving it with two solvents. The purity of the endosulfan-II was finally assigned to be (99.17 ± 0.14)%. Details of the mass balance method including interpretation and evaluating uncertainties of results from each individual methods and the finally assayed purity were also described

  17. STANDARDIZATION OF GLYCOHEMOGLOBIN RESULTS AND REFERENCE VALUES IN WHOLE-BLOOD STUDIED IN 103 LABORATORIES USING 20 METHODS

    NARCIS (Netherlands)

    WEYKAMP, CW; PENDERS, TJ; MUSKIET, FAJ; VANDERSLIK, W

    We investigated the effect of calibration with lyophilized calibrators on whole-blood glycohemoglobin (glyHb) results. One hundred three laboratories, using 20 different methods, determined glyHb in two lyophilized calibrators and two whole-blood samples. For whole-blood samples with low (5%) and

  18. 40 CFR Appendix G to Part 50 - Reference Method for the Determination of Lead in Suspended Particulate Matter Collected From...

    Science.gov (United States)

    2010-07-01

    ... minimize the possibility of generating unreliable data, the user should follow practices established for... chapter—Modifications of methods by users. (Guidance or assistance in requesting approval under Section 2... lead content of the sample is analyzed by atomic absorption spectrometry using an air-acetylene flame...

  19. Evaluation of a new electronic preoperative reference marker for toric intraocular lens implantation by two different methods of analysis: Adobe Photoshop versus iTrace.

    Science.gov (United States)

    Farooqui, Javed Hussain; Sharma, Mansi; Koul, Archana; Dutta, Ranjan; Shroff, Noshir Minoo

    2017-01-01

    The aim of this study is to compare two different methods of analysis of preoperative reference marking for toric intraocular lens (IOL) after marking with an electronic marker. Cataract and IOL Implantation Service, Shroff Eye Centre, New Delhi, India. Fifty-two eyes of thirty patients planned for toric IOL implantation were included in the study. All patients had preoperative marking performed with an electronic preoperative two-step toric IOL reference marker (ASICO AE-2929). Reference marks were placed at 3-and 9-o'clock positions. Marks were analyzed with two systems. First, slit-lamp photographs taken and analyzed using Adobe Photoshop (version 7.0). Second, Tracey iTrace Visual Function Analyzer (version 5.1.1) was used for capturing corneal topograph examination and position of marks noted. Amount of alignment error was calculated. Mean absolute rotation error was 2.38 ± 1.78° by Photoshop and 2.87 ± 2.03° by iTrace which was not statistically significant ( P = 0.215). Nearly 72.7% of eyes by Photoshop and 61.4% by iTrace had rotation error ≤3° ( P = 0.359); and 90.9% of eyes by Photoshop and 81.8% by iTrace had rotation error ≤5° ( P = 0.344). No significant difference in absolute amount of rotation between eyes when analyzed by either method. Difference in reference mark positions when analyzed by two systems suggests the presence of varying cyclotorsion at different points of time. Both analysis methods showed an approximately 3° of alignment error, which could contribute to 10% loss of astigmatic correction of toric IOL. This can be further compounded by intra-operative marking errors and final placement of IOL in the bag.

  20. Stable isotope analyses of oxygen (18O:17O:16O) and chlorine (37Cl:35Cl) in perchlorate: reference materials, calibrations, methods, and interferences

    Science.gov (United States)

    Böhlke, John Karl; Mroczkowski, Stanley J.; Sturchio, Neil C.; Heraty, Linnea J.; Richman, Kent W.; Sullivan, Donald B.; Griffith, Kris N.; Gu, Baohua; Hatzinger, Paul B.

    2017-01-01

    RationalePerchlorate (ClO4−) is a common trace constituent of water, soils, and plants; it has both natural and synthetic sources and is subject to biodegradation. The stable isotope ratios of Cl and O provide three independent quantities for ClO4− source attribution and natural attenuation studies: δ37Cl, δ18O, and δ17O (or Δ17O or 17Δ) values. Documented reference materials, calibration schemes, methods, and interferences will improve the reliability of such studies.MethodsThree large batches of KClO4 with contrasting isotopic compositions were synthesized and analyzed against VSMOW-SLAP, atmospheric O2, and international nitrate and chloride reference materials. Three analytical methods were tested for O isotopes: conversion of ClO4− to CO for continuous-flow IRMS (CO-CFIRMS), decomposition to O2 for dual-inlet IRMS (O2-DIIRMS), and decomposition to O2 with molecular-sieve trap (O2-DIIRMS+T). For Cl isotopes, KCl produced by thermal decomposition of KClO4 was reprecipitated as AgCl and converted into CH3Cl for DIIRMS.ResultsKClO4 isotopic reference materials (USGS37, USGS38, USGS39) represent a wide range of Cl and O isotopic compositions, including non-mass-dependent O isotopic variation. Isotopic fractionation and exchange can affect O isotope analyses of ClO4− depending on the decomposition method. Routine analyses can be adjusted for such effects by normalization, using reference materials prepared and analyzed as samples. Analytical errors caused by SO42−, NO3−, ReO42−, and C-bearing contaminants include isotope mixing and fractionation effects on CO and O2, plus direct interference from CO2 in the mass spectrometer. The results highlight the importance of effective purification of ClO4− from environmental samples.ConclusionsKClO4 reference materials are available for testing methods and calibrating isotopic data for ClO4− and other substances with widely varying Cl or O isotopic compositions. Current ClO4−extraction, purification

  1. Avoided crossings, conical intersections, and low-lying excited states with a single reference method: the restricted active space spin-flip configuration interaction approach.

    Science.gov (United States)

    Casanova, David

    2012-08-28

    The restricted active space spin-flip CI (RASCI-SF) performance is tested in the electronic structure computation of the ground and the lowest electronically excited states in the presence of near-degeneracies. The feasibility of the method is demonstrated by analyzing the avoided crossing between the ionic and neutral singlet states of LiF along the molecular dissociation. The two potential energy surfaces (PESs) are explored by means of the energies of computed adiabatic and approximated diabatic states, dipole moments, and natural orbital electronic occupancies of both states. The RASCI-SF methodology is also used to study the ground and first excited singlet surface crossing involved in the double bond isomerization of ethylene, as a model case. The two-dimensional PESs of the ground (S(0)) and excited (S(1)) states are calculated for the complete configuration space of torsion and pyramidalization molecular distortions. The parameters that define the state energetics in the vicinity of the S(0)/S(1) conical intersection region are compared to complete active space self-consistent field (CASSCF) results. These examples show that it is possible to describe strongly correlated electronic states using a single reference methodology without the need to expand the wavefunction to high levels of collective excitations. Finally, RASCI is also examined in the electronic structure characterization of the ground and 2(1)A(g)(-), 1(1)B(u)(+), 1(1)B(u)(-), and 1(3)B(u)(-) states of all-trans polyenes with two to seven double bonds and beyond. Transition energies are compared to configuration interaction singles, time-dependent density functional theory (TDDFT), CASSCF, and its second-order perturbation correction calculations, and to experimental data. The capability of RASCI-SF to describe the nature and properties of each electronic state is discussed in detail. This example is also used to expose the properties of different truncations of the RASCI wavefunction and to

  2. A comparative proteomics method for multiple samples based on a 18O-reference strategy and a quantitation and identification-decoupled strategy.

    Science.gov (United States)

    Wang, Hongbin; Zhang, Yongqian; Gui, Shuqi; Zhang, Yong; Lu, Fuping; Deng, Yulin

    2017-08-15

    Comparisons across large numbers of samples are frequently necessary in quantitative proteomics. Many quantitative methods used in proteomics are based on stable isotope labeling, but most of these are only useful for comparing two samples. For up to eight samples, the iTRAQ labeling technique can be used. For greater numbers of samples, the label-free method has been used, but this method was criticized for low reproducibility and accuracy. An ingenious strategy has been introduced, comparing each sample against a 18 O-labeled reference sample that was created by pooling equal amounts of all samples. However, it is necessary to use proportion-known protein mixtures to investigate and evaluate this new strategy. Another problem for comparative proteomics of multiple samples is the poor coincidence and reproducibility in protein identification results across samples. In present study, a method combining 18 O-reference strategy and a quantitation and identification-decoupled strategy was investigated with proportion-known protein mixtures. The results obviously demonstrated that the 18 O-reference strategy had greater accuracy and reliability than other previously used comparison methods based on transferring comparison or label-free strategies. By the decoupling strategy, the quantification data acquired by LC-MS and the identification data acquired by LC-MS/MS are matched and correlated to identify differential expressed proteins, according to retention time and accurate mass. This strategy made protein identification possible for all samples using a single pooled sample, and therefore gave a good reproducibility in protein identification across multiple samples, and allowed for optimizing peptide identification separately so as to identify more proteins. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. The evaluation of accuracy of NAA method used by P2TRR laboratory with food standard reference material analysis

    International Nuclear Information System (INIS)

    Rina M, Th.; Sri-Wardhani; Sunarko

    2003-01-01

    The NAA method is the analysis method with high precision and accuracy level. The precision and accuracy of NAA laboratory in P2TRR had been evaluated with SRM 1573a Tomato Leaf and CRM No.9 Sargasso. Samples were irradiated in RSG-GAS's rabbit system and counted with gamma spectrometry. The results obtained from this research are for the SRM 1573a sample the test could analyze 17 elements of the 40 certified elements, and for CRM No.9 sample the test could analyze 16 elements of the 30 certified elements. The result of quantitative analysis indicate the different deviation of each element between 2 -10.5 % compared to the certificate data. This deviation value <15%, this value shows that the precision and accuracy level is good enough

  4. High-grade cervical lesions among women attending a reference clinic in Brazil: associated factors and comparison among screening methods.

    Directory of Open Access Journals (Sweden)

    Neide T Boldrini

    Full Text Available Although screening for cervical cancer is recommended for women in most countries, the incidence of cervical cancer is greater in developing countries. Our goal was to determine the prevalence and factors associated with high-grade lesions/cervical cancer among women attending a reference clinic in Brazil and evaluate the correlation of histology with cytology, colposcopy and the high-risk HPV (HR-HPV tests.A cross-sectional study of women attending a colposcopy clinic was carried out. The patients were interviewed to collect demographic, epidemiological and clinical data. Specimens were collected for cervical cytology, Chlamydia trachomatis and HPV testing using the Hybrid Capture (HC and PCR tests. Colposcopy was performed for all patients and biopsy for histology when cell abnormalities or cervical intraepithelial neoplasia (CIN were present.A total of 291 women participated in the study. The median age was 38 years (DIQ: 30-48 years. The prevalence of histologically confirmed high-grade lesions/cervical cancer was 18.2% (95%, CI: 13.8%-22.6%, with 48 (16.5% cases of CIN-2/CIN-3 and 5 (1.7% cases of invasive carcinoma. In the final logistic regression model, for ages between 30 and 49 years old [OR = 4.4 (95%: 1.01-19.04, history of smoking [OR = 2.4 (95%, CI: 1.14-5.18], practice of anal intercourse [OR = 2.4 (95%, CI: 1.10-5.03] and having positive HC test for HR-HPV [OR = 11.23 (95%, CI: 4 0.79-26, 36] remained independently associated with high-grade lesions/cervical cancer. A total of 64.7% of the cases CIN-3\\Ca in situ were related to HPV-16. Non-oncogenic HPV were only found in CIN-1 biopsy results. Compared to histology, the sensitivity of cytology was 31.8%, the specificity 95.5%; the sensitivity of colposcopy for high-grade lesions/cervical cancer was 51.0%, specificity was 91.4% and the concordance with HPV testing was high.The results confirm an association of HR-HPV with precursor lesions for cervical cancer

  5. Evaluation of RNA extraction methods and identification of putative reference genes for real-time quantitative polymerase chain reaction expression studies on olive (Olea europaea L.) fruits.

    Science.gov (United States)

    Nonis, Alberto; Vezzaro, Alice; Ruperti, Benedetto

    2012-07-11

    Genome wide transcriptomic surveys together with targeted molecular studies are uncovering an ever increasing number of differentially expressed genes in relation to agriculturally relevant processes in olive (Olea europaea L). These data need to be supported by quantitative approaches enabling the precise estimation of transcript abundance. qPCR being the most widely adopted technique for mRNA quantification, preliminary work needs to be done to set up robust methods for extraction of fully functional RNA and for the identification of the best reference genes to obtain reliable quantification of transcripts. In this work, we have assessed different methods for their suitability for RNA extraction from olive fruits and leaves and we have evaluated thirteen potential candidate reference genes on 21 RNA samples belonging to fruit developmental/ripening series and to leaves subjected to wounding. By using two different algorithms, GAPDH2 and PP2A1 were identified as the best reference genes for olive fruit development and ripening, and their effectiveness for normalization of expression of two ripening marker genes was demonstrated.

  6. Discussion Club "Profitable Heritage"

    Directory of Open Access Journals (Sweden)

    Marina Tkacheva

    2017-09-01

    Full Text Available The authors and participants of the project and the expert community analyze the problems related to the realization of a big-scale concept of renovation of the historical center “Irkutsk Quarters”. They discuss preservation of wooden architecture of the city, changes in social functions of the territory, inclusion of the new facilities in the fabric of the area, as well as the problems of the territory’s tourist function and preservation of the identity of Irkutsk downtown.

  7. GLM Proxy Data Generation: Methods for Stroke/Pulse Level Inter-Comparison of Ground-Based Lightning Reference Networks

    Science.gov (United States)

    Cummins, Kenneth L.; Carey, Lawrence D.; Schultz, Christopher J.; Bateman, Monte G.; Cecil, Daniel J.; Rudlosky, Scott D.; Petersen, Walter Arthur; Blakeslee, Richard J.; Goodman, Steven J.

    2011-01-01

    In order to produce useful proxy data for the GOES-R Geostationary Lightning Mapper (GLM) in regions not covered by VLF lightning mapping systems, we intend to employ data produced by ground-based (regional or global) VLF/LF lightning detection networks. Before using these data in GLM Risk Reduction tasks, it is necessary to have a quantitative understanding of the performance of these networks, in terms of CG flash/stroke DE, cloud flash/pulse DE, location accuracy, and CLD/CG classification error. This information is being obtained through inter-comparison with LMAs and well-quantified VLF/LF lightning networks. One of our approaches is to compare "bulk" counting statistics on the spatial scale of convective cells, in order to both quantify relative performance and observe variations in cell-based temporal trends provided by each network. In addition, we are using microsecond-level stroke/pulse time correlation to facilitate detailed inter-comparisons at a more-fundamental level. The current development status of our ground-based inter-comparison and evaluation tools will be presented, and performance metrics will be discussed through a comparison of Vaisala s Global Lightning Dataset (GLD360) with the NLDN at locations within and outside the U.S.

  8. Production and certification of reference materials

    International Nuclear Information System (INIS)

    Sarkis, Jorge Eduardo de S.; Kakazu, Mauricio H.; Hespanhol, Emilio Carlos B.; Martins, Elaine Arantes J.

    1996-01-01

    The reference materials used in analytical chemistry permit us to evaluate correctly the analytical producers as well as experimental set up. U 3 O 8 was produced at IPEN to be used as a secondary standard. We present the first results on U 3 O 8 and discuss the method, preparation, and characterization of that oxide. (author)

  9. Quantification of pneumothorax volume on chest radiographs: comparison between the collins' and the axel's methods with three-dimensional CT as the standard of reference

    International Nuclear Information System (INIS)

    Lee, Chang Keun; Kim, Hyung Jin; Lee, Kyung Hee; Kim, Joung Taek; Kim, Kwang Ho; Suh, Chang Hae; Han, Heon

    1999-01-01

    The purpose of this study was twofold. In a preliminary study, we evaluated the accuracy of 3-D (three-dimensional) CT for the estimation of pneumothorax volume and for providing the optimal postprocessing method for clinical study. In the clinical study, we determined which of the two methods, Collins' and Axel's, was more accurate for the estimation of pneumothorax volume, as seen on chest radiographs, using 3-D CT as the standard of reference. In the preliminary study, 3-D CT was applied to phantoms and to four patients with pneumothorax using two different postprocessing methods, manual contour delineation and thresholding. In the clinical study, 3-D CT was performed in 13 patients with pneumothorax. For the purpose of evaluating conventional radiographs, a localizer scan was used for comparing the accuracy of Collins' method with that of Axel's method, with 3-D CT as the standard of reference. The preliminary study revealed that 3-D CT estimated pneumothorax volume with great accuracy and that manual contour delineation and thresholding measured volume equally well. Because of the shorter postprocessing time required with thresholding than with manual contour delineation (5 min versus 30 min), the former was used during clinical study. The results of this indicated close correlation between the measurements obtained using Collins' method on chest radiographs and those obtained by 3-D CT(r=0.95, p 0.05). 3-D CT can estimate pneumothorax volume with great accuracy. Collins' method is superior to Axel's method for the quantification of pneumothorax volume as seen on chest radiographs

  10. International comparison of the economy of constructing nuclear power plants by using the method of referred investment costs in Czechoslovakia and in the USA

    International Nuclear Information System (INIS)

    Majer, P.; Jelen, J.

    1989-01-01

    The method of referred investment costs was applied to a comparison of the economy of constructing the nuclear power plant at Temelin, Czechoslovakia, with that for the hypothetic nuclear power plant at Middletown, USA. For a reasonably adopted Czechoslovak crown/USD rate, the obtained costs for building the Temelin power plant are 50% higher than those for building the reference Middletown power plant. This compares rather favorably with the general level of investment costs in Czechoslovakia under the present economic conditions. The analysis performed shows that savings in investment costs should be sought in the fields of technological modernization of preparatory work and in all construction work, with the aim to reduce particularly live work. (P.A.). 12 tabs., 8 refs

  11. Panel discussion: Nuclear cardiology

    International Nuclear Information System (INIS)

    Schwaiger, M.

    1991-01-01

    The panel discussion opened with a question concerning whether true quantification of myocardial sympathetic presynaptic function or receptor density can be obtained with currently available radiopharmaceuticals. What are the relative advantages of the two general approaches that have been proposed for quantification: (1) The assessment of tracer distribution volume in tissue following bolus injection and (2) quantification based on tracer displacement kinetics following administration of excess unlabeled tracer. It was pointed out that tracer kinetics for the delineation of presynaptic and postsynaptic binding sites by radiopharmaceuticals or radiolabeled receptor antagonists are rather complex, reflecting several physiologic processes that are difficult to separate. Several approaches were examined. The possibility of regional definition of receptor density by PET was questioned and it was noted that regions of interest can be applied to calculate regional receptor kinetics. However, due to the limited spatial resolution of PET, only average transmural values can be determined. The discussion then turned to the discrepancy between the known sparse parasympathetic innervation of the heart and the high density of muscarinic receptors observed with PET. Experiences with MIBG imaging were reported, including uptake in the transplanted heart and interaction of drugs with MIBG uptake

  12. Empowerment: a conceptual discussion.

    Science.gov (United States)

    Tengland, Per-Anders

    2008-06-01

    The concept of 'empowerment' is used frequently in a number of professional areas, from psychotherapy to social work. But even if the same term is used, it is not always clear if the concept denotes the same goals or the same practice in these various fields. The purpose of this paper is to clarify the discussion and to find a plausible and useful definition of the concept that is suitable for work in various professions. Several suggestions are discussed in the paper, for example control over life or health, autonomy, ability, self-efficacy, self-esteem, and freedom, and it is concluded that there are two plausible complementary uses, one as a goal and one as a process or approach. Empowerment as a goal is to have control over the determinants of one's quality of life, and empowerment as a process is to create a professional relation where the client or community takes control over the change process, determining both the goals of this process and the means to use.

  13. Monitor Clean and Efficient. Background information. Methods and references as applied in the Monitor in April 2009

    International Nuclear Information System (INIS)

    Gerdes, J.; De Ligt, T.

    2010-01-01

    This report contains background information about the Monitor Clean and Efficient that was published in April 2009. The goal and approach of the Monitor are clarified, as well as the methods and data that are used. The structure of this report resembles the structure of the Monitor. Sources and dates of availability are mentioned along with the data, as are the parties collecting and processing the information. The results that were found using this methodology have been published in the Monitor Clean and Efficient. [nl

  14. [Commissioning of the newly constructed Beijing electron-positron collider BEPC, Beijing, China, and visit to SRRC to discuss magnet manufacturing and measurement methods, Taipei, Taiwan, November 11--27, 1988]: Foreign trip report

    International Nuclear Information System (INIS)

    Weng, W.T.

    1988-01-01

    The traveller was invited to IHEP to participate in the commissioning of the newly constructed Beijing electron-positron collider BEPC, give a status report on the AGS Booster Project and to assess the feasibility of sub-contracting booster sextupoles to IHEP. The trip to SRRC was undertaken to discuss magnet manufacturing and measurement methods

  15. The Analysis and Discussion in the Effective Application of the Dispatcher Training Based on Case Teaching Method with the Cause from the Action of the Gap Protection of Main Transformer

    Science.gov (United States)

    Yuanyuan, Xu; Zhengmao, Zhang; Xiang, Fang; Yuanshuai, Xu; Xinxin, Song

    2018-03-01

    The combination of theory and practice is a difficult problem on dispatcher training. Through a typical example of case, this paper provides an effective case teaching method for dispatcher training, and combines the theoretical discussion of the rule of experience with cases and achieves vividness. It helps students to understand and catch the key points of the theory, and improve their practical skills.

  16. Comprehensive profiling of retroviral integration sites using target enrichment methods from historical koala samples without an assembled reference genome

    Directory of Open Access Journals (Sweden)

    Pin Cui

    2016-03-01

    Full Text Available Background. Retroviral integration into the host germline results in permanent viral colonization of vertebrate genomes. The koala retrovirus (KoRV is currently invading the germline of the koala (Phascolarctos cinereus and provides a unique opportunity for studying retroviral endogenization. Previous analysis of KoRV integration patterns in modern koalas demonstrate that they share integration sites primarily if they are related, indicating that the process is currently driven by vertical transmission rather than infection. However, due to methodological challenges, KoRV integrations have not been comprehensively characterized. Results. To overcome these challenges, we applied and compared three target enrichment techniques coupled with next generation sequencing (NGS and a newly customized sequence-clustering based computational pipeline to determine the integration sites for 10 museum Queensland and New South Wales (NSW koala samples collected between the 1870s and late 1980s. A secondary aim of this study sought to identify common integration sites across modern and historical specimens by comparing our dataset to previously published studies. Several million sequences were processed, and the KoRV integration sites in each koala were characterized. Conclusions. Although the three enrichment methods each exhibited bias in integration site retrieval, a combination of two methods, Primer Extension Capture and hybridization capture is recommended for future studies on historical samples. Moreover, identification of integration sites shows that the proportion of integration sites shared between any two koalas is quite small.

  17. Use of fat mass and fat free mass standard deviation scores obtained using simple measurement methods in healthy children and patients: comparison with the reference 4-component model.

    Science.gov (United States)

    Atherton, Rachel R; Williams, Jane E; Wells, Jonathan C K; Fewtrell, Mary S

    2013-01-01

    Clinical application of body composition (BC) measurements for individual children has been limited by lack of appropriate reference data. (1) To compare fat mass (FM) and fat free mass (FFM) standard deviation scores (SDS) generated using new body composition reference data and obtained using simple measurement methods in healthy children and patients with those obtained using the reference 4-component (4-C) model; (2) To determine the extent to which scores from simple methods agree with those from the 4-C model in identification of abnormal body composition. FM SDS were calculated for 4-C model, dual-energy X-ray absorptiometry (DXA; GE Lunar Prodigy), BMI and skinfold thicknesses (SFT); and FFM SDS for 4CM, DXA and bioelectrical impedance analysis (BIA; height(2)/Z)) in 927 subjects aged 3.8-22.0 y (211 healthy, 716 patients). DXA was the most accurate method for both FM and FFM SDS in healthy subjects and patients (mean bias (limits of agreement) FM SDS 0.03 (± 0.62); FFM SDS -0.04 (± 0.72)), and provided best agreement with the 4-C model in identifying abnormal BC (SDS ≤-2 or ≥ 2). BMI and SFTs were reasonable predictors of abnormal FM SDS, but poor in providing an absolute value. BIA was comparable to DXA for FFM SDS and in identifying abnormal subjects. DXA may be used both for research and clinically to determine FM and FFM SDS. BIA may be used to assess FFM SDS in place of DXA. BMI and SFTs can be used to measure adiposity for groups but not individuals. The performance of simpler techniques in monitoring longitudinal BC changes requires investigation. Ultimately, the most appropriate method should be determined by its predictive value for clinical outcome.

  18. Use of fat mass and fat free mass standard deviation scores obtained using simple measurement methods in healthy children and patients: comparison with the reference 4-component model.

    Directory of Open Access Journals (Sweden)

    Rachel R Atherton

    Full Text Available BACKGROUND: Clinical application of body composition (BC measurements for individual children has been limited by lack of appropriate reference data. OBJECTIVES: (1 To compare fat mass (FM and fat free mass (FFM standard deviation scores (SDS generated using new body composition reference data and obtained using simple measurement methods in healthy children and patients with those obtained using the reference 4-component (4-C model; (2 To determine the extent to which scores from simple methods agree with those from the 4-C model in identification of abnormal body composition. DESIGN: FM SDS were calculated for 4-C model, dual-energy X-ray absorptiometry (DXA; GE Lunar Prodigy, BMI and skinfold thicknesses (SFT; and FFM SDS for 4CM, DXA and bioelectrical impedance analysis (BIA; height(2/Z in 927 subjects aged 3.8-22.0 y (211 healthy, 716 patients. RESULTS: DXA was the most accurate method for both FM and FFM SDS in healthy subjects and patients (mean bias (limits of agreement FM SDS 0.03 (± 0.62; FFM SDS -0.04 (± 0.72, and provided best agreement with the 4-C model in identifying abnormal BC (SDS ≤-2 or ≥ 2. BMI and SFTs were reasonable predictors of abnormal FM SDS, but poor in providing an absolute value. BIA was comparable to DXA for FFM SDS and in identifying abnormal subjects. CONCLUSIONS: DXA may be used both for research and clinically to determine FM and FFM SDS. BIA may be used to assess FFM SDS in place of DXA. BMI and SFTs can be used to measure adiposity for groups but not individuals. The performance of simpler techniques in monitoring longitudinal BC changes requires investigation. Ultimately, the most appropriate method should be determined by its predictive value for clinical outcome.

  19. Comparison of Capability of Digitizing Methods to Predict Soil classification According to the Soil Taxonomy and World Reference Base for Soil Resources

    Directory of Open Access Journals (Sweden)

    zohreh mosleh

    2017-02-01

    Full Text Available Introduction: Soil classification generally aims to establish a taxonomy based on breaking the soil continuum into homogeneous groups that can highlight the essential differences in soil properties and functions between classes.The two most widely used modern soil classification schemes are Soil Taxonomy (ST and World Reference Base for Soil Resources (WRB.With the development of computers and technology, digital and quantitative approaches have been developed. These new techniques that include the spatial prediction of soil properties or classes, relies on finding the relationships between soil and the auxiliary information that explain the soil forming factors or processes and finally predict soil patterns on the landscape. These approaches are commonly referred to as digital soil mapping (DSM (14. A key component of any DSM mapping activity is the method used to define the relationship between soil observation and auxiliary information (4. Several types of machine learning approaches have been applied for digital soil mapping of soil classes, such as logistic and multinomial logistic regressions (10,12, random forests (15, neural networks (3,13 and classification trees (22,4. Many decisions about the soil use and management are based on the soil differences that cannot be captured by higher taxonomic levels (i.e., order, suborder and great group (4. In low relief areas such as plains, it is expected that the soil forming factors are more homogenous and auxiliary information explaining soil forming factors may have low variation and cannot show the soil variability. Materials and Methods: The study area is located in the Shahrekord plain of Chaharmahal-Va-Bakhtiari province. According tothe semi-detailed soil survey (16, 120 pedons with approximate distance of 750 m were excavated and described according to the “field book for describing and sampling soils” (19. Soil samples were taken from different genetic horizons, air dried and

  20. Results and discussion

    International Nuclear Information System (INIS)

    1998-01-01

    The author deals with the experimental study of sorption, desorption and vertical migration of radionuclides in Sr-85 and Cs-137 in selected soil samples from around of NPP Bohunice and NPP Mochovce and other localities of the Slovakia. The influence of different materials [concurrent ions (K + , Ca 2+ , NH 4 + , pH), organic matter (peat) and zeolite, humidity] on kinetic of sorption and desorption of strontium and cesium as well as distribution coefficient (K D ) and transfer coefficients in followed samples of soils were followed. Obtained adsorption isotherm are presented and discussed. Using the Tessiere's sequential extraction analysis a gross variability in binding of radionuclides on soils was found. The obtained results were processed with the correlation analysis and the compartment model

  1. Open discussions on nuclear energy

    International Nuclear Information System (INIS)

    1978-01-01

    In the first part, economic prospects in the world and in the European Community and their repercussions on energy demand are examined. Supply structure and growth scenari are outlined. Present and potential contribution of nuclear energy to energy supply is developed. The pros and cons are given. In the second part is examined how the production and use of various form of energy including nuclear energy, can affect health and the environment, with special reference to waste of all kinds. Safety problems and risk of accidents are examined in both non nuclear and nuclear sectors. Prospects for a low energy society and economic and social implications of the use of new forms of energy are also discussed

  2. Panel discussion. Session 1

    International Nuclear Information System (INIS)

    Rodgers, B.R.

    1986-01-01

    An attempt is made to identify problems that need research and development work in order to advance low-level radioactive waste technology and to put the industry in a better position in five to ten years, or even twenty-five years from now. Attention is focused on disposal methods, operating procedures, the effects of the establishment of the state compact, and de minimis criteria

  3. The calculation of dose from external photon exposures using reference human phantoms and Monte Carlo methods. Pt. 6

    International Nuclear Information System (INIS)

    Zankl, M.; Panzer, W.; Drexler, G.

    1991-11-01

    Computed tomography (CT) is a technique which offers a high diagnostic capability; however, the dose to the patient is high compared to conventional radiography. This report provides a catalogue of organ doses resulting from CT examinations. The organ doses were calculated for the type of CT scanners most commonly used in the FRG and for three different radiation qualities. For the dose calculations, the patients were represented by the adult mathematical phantoms Adam and Eva. The radiation transport in the body was simulated using a Monte Carlo method. The doses were calculated as conversion factors of mean organ doses per air kerma free in air on the axis of rotation. Mean organ dose conversion factors are given per organ and per single CT slice of 1 cm width. The mean dose to an organ resulting from a particular CT examination can be estimated by summing up the contribution to the organ dose from each relevant slice. In order to facilitate the selection of the appropriate slices, a table is given which relates the mathematical phantoms' coordinates to certain anatomical landmarks in the human body. (orig.)

  4. Final plenary discussion

    International Nuclear Information System (INIS)

    Federline, M.

    2004-01-01

    Rapporteur, chose to highlight other themes and issues from the seminar that appeared to be: - important for successful D and D; - worth further work in an international context; - controversial and worthy of further debate. The five main themes selected were as follows: - stakeholder involvement and communication; - strategy selection; - waste management and clearance; - funding and costs; - satisfying social demands. Various issues were identified under each one of these five themes and, in order to make best use of the time available for discussion, participants were invited to vote on the issues of most importance to them. Subsequent discussion was then focussed on the issues so identified. (author)

  5. Evaluating new HbA1c methods for adoption by the IFCC and NGSP reference networks using international quality targets.

    Science.gov (United States)

    Lenters-Westra, Erna; English, Emma

    2017-08-28

    As a reference laboratory for HbA1c, it is essential to have accurate and precise HbA1c methods covering a range of measurement principles. We report an evaluation of the Abbott Enzymatic (Architect c4000), Roche Gen.3 HbA1c (Cobas c513) and Tosoh G11 using different quality targets. The effect of hemoglobin variants, other potential interferences and the performance in comparison to both the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) and the National Glycohemoglobin Standardization Program (NGSP) reference systems was assessed using certified evaluation protocols. Each of the evaluated HbA1c methods had CVs HbA1c. Partly based on the result of this study, the Abbott Enzymatic method on the Architect c4000 and the Roche Gen.3 HbA1c on the Cobas c513 are now official, certified IFCC and NGSP SRMPs in the IFCC and NGSP networks. Sigma metrics quality criteria presented in a graph distinguish between good and excellent performance.

  6. Development of real-time PCR method for the detection and the quantification of a new endogenous reference gene in sugar beet "Beta vulgaris L.": GMO application.

    Science.gov (United States)

    Chaouachi, Maher; Alaya, Akram; Ali, Imen Ben Haj; Hafsa, Ahmed Ben; Nabi, Nesrine; Bérard, Aurélie; Romaniuk, Marcel; Skhiri, Fethia; Saïd, Khaled

    2013-01-01

    KEY MESSAGE : Here, we describe a new developed quantitative real-time PCR method for the detection and quantification of a new specific endogenous reference gene used in GMO analysis. The key requirement of this study was the identification of a new reference gene used for the differentiation of the four genomic sections of the sugar beet (Beta vulgaris L.) (Beta, Corrollinae, Nanae and Procumbentes) suitable for quantification of genetically modified sugar beet. A specific qualitative polymerase chain reaction (PCR) assay was designed to detect the sugar beet amplifying a region of the adenylate transporter (ant) gene only from the species of the genomic section I of the genus Beta (cultivated and wild relatives) and showing negative PCR results for 7 species of the 3 other sections, 8 related species and 20 non-sugar beet plants. The sensitivity of the assay was 15 haploid genome copies (HGC). A quantitative real-time polymerase chain reaction (QRT-PCR) assay was also performed, having high linearity (R (2) > 0.994) over sugar beet standard concentrations ranging from 20,000 to 10 HGC of the sugar beet DNA per PCR. The QRT-PCR assay described in this study was specific and more sensitive for sugar beet quantification compared to the validated test previously reported in the European Reference Laboratory. This assay is suitable for GMO quantification in routine analysis from a wide variety of matrices.

  7. Fuel ethanol discussion paper

    International Nuclear Information System (INIS)

    1992-01-01

    In recognition of the potential benefits of ethanol and the merits of encouraging value-added agricultural development, a committee was formed to develop options for the role of the Ontario Ministry of Agriculture and Food in the further development of the ethanol industry in Ontario. A consultation with interested parties produced a discussion paper which begins with an outline of the role of ethanol as an alternative fuel. Ethanol issues which require industry consideration are presented, including the function of ethanol as a gasoline oxygenate or octane enhancer, environmental impacts, energy impacts, agricultural impacts, trade and fiscal implications, and regulation. The ethanol industry and distribution systems in Ontario are then described. The current industry consists of one ethanol plant and over 30 retail stations. The key issue for expanding the industry is the economics of producing ethanol. At present, production of ethanol in the short term depends on tax incentives amounting to 23.2 cents/l. In the longer term, a significant reduction in feedstock costs and a significant improvement in processing technology, or equally significant gasoline price increases, will be needed to create a sustainable ethanol industry that does not need incentives. Possible roles for the Ministry are identified, such as support for ethanol research and development, financial support for construction of ethanol plants, and active encouragement of market demand for ethanol-blended gasolines

  8. A Reference-Free and Non-Contact Method for Detecting and Imaging Damage in Adhesive-Bonded Structures Using Air-Coupled Ultrasonic Transducers

    Directory of Open Access Journals (Sweden)

    Timotius Yonathan Sunarsa

    2017-12-01

    Full Text Available Adhesive bonded structures have been widely used in aerospace, automobile, and marine industries. Due to the complex nature of the failure mechanisms of bonded structures, cost-effective and reliable damage detection is crucial for these industries. Most of the common damage detection methods are not adequately sensitive to the presence of weakened bonding. This paper presents an experimental and analytical method for the in-situ detection of damage in adhesive-bonded structures. The method is fully non-contact, using air-coupled ultrasonic transducers (ACT for ultrasonic wave generation and sensing. The uniqueness of the proposed method relies on accurate detection and localization of weakened bonding in complex adhesive bonded structures. The specimens tested in this study are parts of real-world structures with critical and complex damage types, provided by Hyundai Heavy Industries® and IKTS Fraunhofer®. Various transmitter and receiver configurations, including through transmission, pitch-catch scanning, and probe holder angles, were attempted, and the obtained results were analyzed. The method examines the time-of-flight of the ultrasonic waves over a target inspection area, and the spatial variation of the time-of-flight information was examined to visualize and locate damage. The proposed method works without relying on reference data obtained from the pristine condition of the target specimen. Aluminum bonded plates and triplex adhesive layers with debonding and weakened bonding were used to examine the effectiveness of the method.

  9. Different percentages of false-positive results obtained using five methods for the calculation of reference change values based on simulated normal and ln-normal distributions of data

    DEFF Research Database (Denmark)

    Lund, Flemming; Petersen, Per Hyltoft; Fraser, Callum G

    2016-01-01

    a homeostatic set point that follows a normal (Gaussian) distribution. This set point (or baseline in steady-state) should be estimated from a set of previous samples, but, in practice, decisions based on reference change value are often based on only two consecutive results. The original reference change value......-positive results. The aim of this study was to investigate false-positive results using five different published methods for calculation of reference change value. METHODS: The five reference change value methods were examined using normally and ln-normally distributed simulated data. RESULTS: One method performed...... best in approaching the theoretical false-positive percentages on normally distributed data and another method performed best on ln-normally distributed data. The commonly used reference change value method based on two results (without use of estimated set point) performed worst both on normally...

  10. Digital reference service : libraries online 24/7

    OpenAIRE

    Vijayakumar, Manju; Vijayakumar, J. K.

    2005-01-01

    The integration of the Internet Technology in to Libraries has not changed its mission of providing excellent information service to users but it has added several new dimensions and opened new avenues to their tasks. Reference librarians, while assisting users in the library, now have an additional set of remote users, who access the reference service online, who are more demanding, less patient users who have greater expectations. This paper discusses the methods in Online Reference service...

  11. Definition of the upper reference limit for thyroglobulin antibodies according to the National Academy of Clinical Biochemistry guidelines: comparison of eleven different automated methods.

    Science.gov (United States)

    D'Aurizio, F; Metus, P; Ferrari, A; Caruso, B; Castello, R; Villalta, D; Steffan, A; Gaspardo, K; Pesente, F; Bizzaro, N; Tonutti, E; Valverde, S; Cosma, C; Plebani, M; Tozzoli, R

    2017-12-01

    In the last two decades, thyroglobulin autoantibodies (TgAb) measurement has progressively switched from marker of thyroid autoimmunity to test associated with thyroglobulin (Tg) to verify the presence or absence of TgAb interference in the follow-up of patients with differentiated thyroid cancer. Of note, TgAb measurement is cumbersome: despite standardization against the International Reference Preparation MRC 65/93, several studies demonstrated high inter-method variability and wide variation in limits of detection and in reference intervals. Taking into account the above considerations, the main aim of the present study was the determination of TgAb upper reference limit (URL), according to the National Academy of Clinical Biochemistry guidelines, through the comparison of eleven commercial automated immunoassay platforms. The sera of 120 healthy males, selected from a population survey in the province of Verona, Italy, were tested for TgAb concentration using eleven IMA applied on as many automated analyzers: AIA-2000 (AIA) and AIA-CL2400 (CL2), Tosoh Bioscience; Architect (ARC), Abbott Diagnostics; Advia Centaur XP (CEN) and Immulite 2000 XPi (IMM), Siemens Healthineers; Cobas 6000 (COB), Roche Diagnostics; Kryptor (KRY), Thermo Fisher Scientific BRAHMS, Liaison XL (LIA), Diasorin; Lumipulse G (LUM), Fujirebio; Maglumi 2000 Plus (MAG), Snibe and Phadia 250 (PHA), Phadia AB, Thermo Fisher Scientific. All assays were performed according to manufacturers' instructions in six different laboratories in Friuli-Venezia Giulia and Veneto regions of Italy [Lab 1 (AIA), Lab 2 (CL2), Lab 3 (ARC, COB and LUM), Lab 4 (CEN, IMM, KRY and MAG), Lab 5 (LIA) and Lab 6 (PHA)]. Since TgAb values were not normally distributed, the experimental URL (e-URL) was established at 97.5 percentile according to the non-parametric method. TgAb e-URLs showed a significant inter-method variability. Considering the same method, e-URL was much lower than that suggested by manufacturers (m

  12. The role of nuclear methods in the study of surface compositions. Their use in the Community Bureau of Reference (BCR). Project on 'RMs for non-metals in non-ferrous metals'

    International Nuclear Information System (INIS)

    Quaglia, L.; Weber, G.

    1979-01-01

    The preparation of high-purity materials poses the problem of the analysis of the elements present at very low concentrations, even below 1 μg/g. For different analysis methods an important source of systematic errors is surface pollution. Although nuclear methods have shown to be well suited for the quantitative study of surfaces, their possibilities remain insufficiently known for most non-nuclear laboratories. Therefore, the first part of this report was conceived as a simple but complete as possible review of the existing nuclear techniques and gives also a description of their principal characteristics. The second part treats special uses of some of these techniques, especially the study of surface-mass interferences in the case of the assay of light elements in metals and alloys. This problem is discussed in the framework of the certification of reference materials, and is based upon experiences collected in a ten-year Community effort, which enabled the expression of general considerations concerning the treatment, conditioning and storage of reference materials

  13. The location of midfacial landmarks according to the method of establishing the midsagittal reference plane in three-dimensional computed tomography analysis of facial asymmetry

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Min Sun; Lee, Eun Joo; Lee, Jae Seo; Kang, Byung Cheock; Yoon, Suk Ja [Dental Science Research Institute, Chonnam National University, Gwangju (Korea, Republic of); Song, In Ja [Dept. of Nursing, Kwangju Women' s University, Gwangju (Korea, Republic of)

    2015-12-15

    The purpose of this study was to evaluate the influence of methods of establishing the midsagittal reference plane (MRP) on the locations of midfacial landmarks in the three-dimensional computed tomography (CT) analysis of facial asymmetry. A total of 24 patients (12 male and 12 female; mean age, 22.5 years; age range, 18.2-29.7 years) with facial asymmetry were included in this study. The MRP was established using two different methods on each patient's CT image. The x-coordinates of four midfacial landmarks (the menton, nasion, upper incisor, and lower incisor) were obtained by measuring the distance and direction of the landmarks from the MRP, and the two methods were compared statistically. The direction of deviation and the severity of asymmetry found using each method were also compared. The x-coordinates of the four anatomic landmarks all showed a statistically significant difference between the two methods of establishing the MRP. For the nasion and lower incisor, six patients (25.0%) showed a change in the direction of deviation. The severity of asymmetry also changed in 16 patients (66.7%). The results of this study suggest that the locations of midfacial landmarks change significantly according to the method used to establish the MRP.

  14. Fast and fuzzy multi-objective radiotherapy treatment plan generation for head and neck cancer patients with the lexicographic reference point method (LRPM)

    Science.gov (United States)

    van Haveren, Rens; Ogryczak, Włodzimierz; Verduijn, Gerda M.; Keijzer, Marleen; Heijmen, Ben J. M.; Breedveld, Sebastiaan

    2017-06-01

    Previously, we have proposed Erasmus-iCycle, an algorithm for fully automated IMRT plan generation based on prioritised (lexicographic) multi-objective optimisation with the 2-phase ɛ-constraint (2pɛc) method. For each patient, the output of Erasmus-iCycle is a clinically favourable, Pareto optimal plan. The 2pɛc method uses a list of objective functions that are consecutively optimised, following a strict, user-defined prioritisation. The novel lexicographic reference point method (LRPM) is capable of solving multi-objective problems in a single optimisation, using a fuzzy prioritisation of the objectives. Trade-offs are made globally, aiming for large favourable gains for lower prioritised objectives at the cost of only slight degradations for higher prioritised objectives, or vice versa. In this study, the LRPM is validated for 15 head and neck cancer patients receiving bilateral neck irradiation. The generated plans using the LRPM are compared with the plans resulting from the 2pɛc method. Both methods were capable of automatically generating clinically relevant treatment plans for all patients. For some patients, the LRPM allowed large favourable gains in some treatment plan objectives at the cost of only small degradations for the others. Moreover, because of the applied single optimisation instead of multiple optimisations, the LRPM reduced the average computation time from 209.2 to 9.5 min, a speed-up factor of 22 relative to the 2pɛc method.

  15. 石子表观密度简易检测新方法探讨%The discussion of new methods about the apparent density of stones with simple method

    Institute of Scientific and Technical Information of China (English)

    赵清; 李进; 袁慧; 程煜

    2015-01-01

    The paper introduces some stone apparent density detection methods. Through comparing it to liquid balance method,overflow channel method and improved wild-mouth bottle method,it concludes that stone apparent density detection method is a kind of new method,and explores stone detection accuracy for stones with various diameters and stones with similar diameters and various testing times,and finally points out that:the improved wild-mouth bottle method is the most efficient and accurate stone apparent density detection method.%介绍了几种检测石子表观密度的方法,通过比较液体天平法、溢流水槽法和改进的广口瓶法,得出了检测石子表观密度的一种新方法———改进的广口瓶法,进而探讨了该方法对不同粒径的石子和相同粒径不同试验次数的石子检测的准确性,指出改进的广口瓶法是一种更高效、准确的石子表观密度检测方法。

  16. Implementation of the method air-kerma product area in KAP camera calibration with reference qualities of X-ray series at the SSDL RQR of Mexico

    International Nuclear Information System (INIS)

    Cejudo, Jesus; Tovar, Victor M.

    2013-01-01

    The X-Ray machines, at a reference laboratory for the instrument calibration in diagnostic radiology, should compliance with the ISO requirements. Sometimes there is not available as much laboratories as needed in Latin American countries. So this project shows the KAP ionization chamber implementation method using the TRS-457 radiation quality from the IAEA at the SSDL of Mexico. The KAP instruments calibration method consists in doing a substitution comparison using a standard reference with traceability to a primary laboratory and a transmission-monitoring chamber that measures the number of photons of the X-ray primary beam. A KAP chamber calibration requires a special array that consists in collocating the chamber in two different positions of its calibration process. Then, with air kerma-area product coefficient together with a corrected electrometer measure at referential conditions, the patient dosimetry magnitudes are calculated. The dosimetry necessity at hospitals always will be in function of possessing a highly reliable calibration coefficient chamber for making these measures. That dosimetry results will help in reducing the total or partial irradiation emitted to the human body of the patient. This is how stochastic risks will be lessened due to diagnostic studies. The purpose of this project is to have a synergy with calibration for making known that the SSDL of Mexico has the technical capacity to act as a link between primary standard dosimetry laboratories and the ionizing radiation equipment users who require that their KAP chamber have traceability from the primary standard to the user. (author)

  17. Towards absolute quantification of allergenic proteins in food--lysozyme in wine as a model system for metrologically traceable mass spectrometric methods and certified reference materials.

    Science.gov (United States)

    Cryar, Adam; Pritchard, Caroline; Burkitt, William; Walker, Michael; O'Connor, Gavin; Burns, Duncan Thorburn; Quaglia, Milena

    2013-01-01

    Current routine food allergen quantification methods, which are based on immunochemistry, offer high sensitivity but can suffer from issues of specificity and significant variability of results. MS approaches have been developed, but currently lack metrological traceability. A feasibility study on the application of metrologically traceable MS-based reference procedures was undertaken. A proof of concept involving proteolytic digestion and isotope dilution MS for quantification of protein allergens in a food matrix was undertaken using lysozyme in wine as a model system. A concentration of lysozyme in wine of 0.95 +/- 0.03 microg/g was calculated based on the concentrations of two peptides, confirming that this type of analysis is viable at allergenically meaningful concentrations. The challenges associated with this promising method were explored; these included peptide stability, chemical modification, enzymatic digestion, and sample cleanup. The method is suitable for the production of allergen in food certified reference materials, which together with the achieved understanding of the effects of sample preparation and of the matrix on the final results, will assist in addressing the bias of the techniques routinely used and improve measurement confidence. Confirmation of the feasibility of MS methods for absolute quantification of an allergenic protein in a food matrix with results traceable to the International System of Units is a step towards meaningful comparison of results for allergen proteins among laboratories. This approach will also underpin risk assessment and risk management of allergens in the food industry, and regulatory compliance of the use of thresholds or action levels when adopted.

  18. Geotechnical site assessment methodologies relevant to potential deep underground disposal facilities: with particular reference to the determination of in situ rock stress by the hydraulic fracturing method

    International Nuclear Information System (INIS)

    Monaghan, B.G.; Richards, L.R.

    1986-10-01

    A final report summarizing the research conducted on geotechnical site assessment methodologies relevant to Land 3/4 sites. Two areas of research have been investigated; in situ stress determination by the hydraulic fracturing method in basic volcanics and sediments and the laboratory determination of hydraulic fracture tensile strength. The analysis and interpretation of the hydraulic fracturing test data from a programme of testing in the Vale of Belvoir is discussed in detail particularly in respect of the effects of pore water pressure and fluid diffusion in the rocks being tested. The regional stress regime of the Vale of Belvoir is discussed with respect to the results of the in situ stress determination. A method for determining the hydraulic fracture tensile strength in the laboratory is described. The results of a series of laboratory tests on rock core are reported. (author)

  19. Usefulness of quantitative determination of cerebral blood flow by 123I-IMP SPECT reference sample method in various cerebrovascular disorders

    International Nuclear Information System (INIS)

    Fukuda, Tadaharu; Hasegawa, Kouichi; Yamanaka, Shigehito; Hasue, Masamichi; Ohtubo, Yutaka; Wada, Atsushi; Nakanishi, Hisashi; Nakamura, Tatuya; Itou, Hiroshi.

    1992-01-01

    Cerebral blood flow (CBF) was quantitatively determined by N-isopropyl-p-[ 123 I] iodo-amphetamine (IMP) single photon emission computed tomography (SPECT) with a rotating gamma camera. A ZLC 7500 unit (SIEMENS Inc.) was used for emission CT, and a SCINTIPAK-2400 (Shimadzu Corp. Ltd.) for data processing. For the quantitative determination of CBF, arterial blood samples were collected for 5 minutes during the intravenous injection of 111 MBq of IMP, and a reference sample method corrected by time-activity curve was used. The determination was carried out in 90 patients with various cerebrovascular diseases and 5 normal volunteers. Mean cerebral blood flow (m-CBF) in the normal cases as determined by the above method was 42.4±6.0 (ml/100g/min). In patients with acute phase subarachnoid hemorrhage (SAH), severity on CT was marked in patients with intracerebral hematomas greater than 45 mm in diameter. Patients with non-hemorrhagic arteriovenous malfomation (AVM) whose nidi were 30 mm or more in diameter showed a decrease in CBF on the afferent side. This decrease was caused by a steal phenomenon affecting CBF around the AVM. The size of cerebral infarction on CT was closely correlated with the decrease in CBF, and CBF in patients with stenosis and obstruction of the main trunks was less than that in patients without them. CBF was increased by 10-20% in patients who underwent carotid endarterectomy or superior temporal artery-middle cerebral artery anastomosis for obstruction or stenosis of the internal carotid artery or the middle cerebral artery. The quantitative determination of CBF by IMP SPECT reference sample method was useful for evaluating the morbid condition and estimating the prognosis of cerebrovascular diseases, and evaluating the effects of therapy. (J.P.N.)

  20. ENRAF gauge reference level calculations

    Energy Technology Data Exchange (ETDEWEB)

    Huber, J.H., Fluor Daniel Hanford

    1997-02-06

    This document describes the method for calculating reference levels for Enraf Series 854 Level Detectors as installed in the tank farms. The reference level calculation for each installed level gauge is contained herein.

  1. Global Reference Tables Services Architecture

    Data.gov (United States)

    Social Security Administration — This database stores the reference and transactional data used to provide a data-driven service access method to certain Global Reference Table (GRT) service tables.

  2. Development of a highly precise ID-ICP-SFMS method for analysis of low concentrations of lead in rice flour reference materials.

    Science.gov (United States)

    Zhu, Yanbei; Inagaki, Kazumi; Yarita, Takashi; Chiba, Koichi

    2008-07-01

    Microwave digestion and isotope dilution inductively coupled plasma mass spectrometry (ID-ICP-SFMS) has been applied to the determination of Pb in rice flour. In order to achieve highly precise determination of low concentrations of Pb, the digestion blank for Pb was reduced to 0.21 ng g(-1) after optimization of the digestion conditions, in which 20 mL analysis solution was obtained after digestion of 0.5 g rice flour. The observed value of Pb in a non-fat milk powder certified reference material (CRM), NIST SRM 1549, was 16.8 +/- 0.8 ng g(-1) (mean +/- expanded uncertainty, k = 2; n = 5), which agreed with the certified value of 19 +/- 3 ng g(-1) and indicated the effectiveness of the method. Analytical results for Pb in three brown rice flour CRMs, NIST SRM 1568a, NIES CRM 10-a, and NIES CRM 10-b, were 7.32 +/- 0.24 ng g(-1) (n = 5), 1010 +/- 10 ng g(-1) (n = 5), and 1250 +/- 20 ng g(-1) (n = 5), respectively. The concentration of Pb in a candidate white rice flour reference material (RM) sample prepared by the National Metrology Institute of Japan (NMIJ) was observed to be 4.36 +/- 0.28 ng g(-1) (n = 10 bottles).

  3. Uranium reference materials

    International Nuclear Information System (INIS)

    Donivan, S.; Chessmore, R.

    1987-07-01

    The Technical Measurements Center has prepared uranium mill tailings reference materials for use by remedial action contractors and cognizant federal and state agencies. Four materials were prepared with varying concentrations of radionuclides, using three tailings materials and a river-bottom soil diluent. All materials were ground, dried, and blended thoroughly to ensure homogeneity. The analyses on which the recommended values for nuclides in the reference materials are based were performed, using independent methods, by the UNC Geotech (UNC) Chemistry Laboratory, Grand Junction, Colorado, and by C.W. Sill (Sill), Idaho National Engineering Laboratory, Idaho Falls, Idaho. Several statistical tests were performed on the analytical data to characterize the reference materials. Results of these tests reveal that the four reference materials are homogeneous and that no large systematic bias exists between the analytical methods used by Sill and those used by TMC. The average values for radionuclides of the two data sets, representing an unbiased estimate, were used as the recommended values for concentrations of nuclides in the reference materials. The recommended concentrations of radionuclides in the four reference materials are provided. Use of these reference materials will aid in providing uniform standardization among measurements made by remedial action contractors. 11 refs., 9 tabs

  4. Discussion

    International Nuclear Information System (INIS)

    Mittleman, M.H.

    1985-01-01

    The positive energy projection operators, just described by Prof. Sucher, convert the sick Hamiltonian, H/sub DC/, into a more robust one which can support bound states. They are however still a subject of some controversy. Prof. Grant pointed out that existing computer codes produce remarkable accuracy in numerical calculations which start from H/sub DC/ (with no projection operators) and so he questioned whether these operators were indeed necessary. In response, it was pointed out by several people in the audience that the codes implicitly limit the Dirac-Hartee-Fock wave functions to a normalizable sub-space and that this operation can be described as a projection operator which has the effect of eliminating the negative energy states which are not normalizable. This operation is however, not any of the three projection operators described by Sucher and so the question arises as to the sensitivity of the results (for the energy and wave functions) to the particular projection operators which are used. This appears to be an open question

  5. Selecting the optimal method to calculate daily global reference potential evaporation from CFSR reanalysis data for application in a hydrological model study

    Directory of Open Access Journals (Sweden)

    F. C. Sperna Weiland

    2012-03-01

    Full Text Available Potential evaporation (PET is one of the main inputs of hydrological models. Yet, there is limited consensus on which PET equation is most applicable in hydrological climate impact assessments. In this study six different methods to derive global scale reference PET daily time series from Climate Forecast System Reanalysis (CFSR data are compared: Penman-Monteith, Priestley-Taylor and original and re-calibrated versions of the Hargreaves and Blaney-Criddle method. The calculated PET time series are (1 evaluated against global monthly Penman-Monteith PET time series calculated from CRU data and (2 tested on their usability for modeling of global discharge cycles.

    A major finding is that for part of the investigated basins the selection of a PET method may have only a minor influence on the resulting river flow. Within the hydrological model used in this study the bias related to the PET method tends to decrease while going from PET, AET and runoff to discharge calculations. However, the performance of individual PET methods appears to be spatially variable, which stresses the necessity to select the most accurate and spatially stable PET method. The lowest root mean squared differences and the least significant deviations (95% significance level between monthly CFSR derived PET time series and CRU derived PET were obtained for a cell-specific re-calibrated Blaney-Criddle equation. However, results show that this re-calibrated form is likely to be unstable under changing climate conditions and less reliable for the calculation of daily time series. Although often recommended, the Penman-Monteith equation applied to the CFSR data did not outperform the other methods in a evaluation against PET derived with the Penman-Monteith equation from CRU data. In arid regions (e.g. Sahara, central Australia, US deserts, the equation resulted in relatively low PET values and, consequently, led to relatively high discharge values for dry basins (e

  6. Towards a universal method for calculating hydration free energies: a 3D reference interaction site model with partial molar volume correction.

    Science.gov (United States)

    Palmer, David S; Frolov, Andrey I; Ratkova, Ekaterina L; Fedorov, Maxim V

    2010-12-15

    We report a simple universal method to systematically improve the accuracy of hydration free energies calculated using an integral equation theory of molecular liquids, the 3D reference interaction site model. A strong linear correlation is observed between the difference of the experimental and (uncorrected) calculated hydration free energies and the calculated partial molar volume for a data set of 185 neutral organic molecules from different chemical classes. By using the partial molar volume as a linear empirical correction to the calculated hydration free energy, we obtain predictions of hydration free energies in excellent agreement with experiment (R = 0.94, σ = 0.99 kcal mol (- 1) for a test set of 120 organic molecules).

  7. Towards a universal method for calculating hydration free energies: a 3D reference interaction site model with partial molar volume correction

    International Nuclear Information System (INIS)

    Palmer, David S; Frolov, Andrey I; Ratkova, Ekaterina L; Fedorov, Maxim V

    2010-01-01

    We report a simple universal method to systematically improve the accuracy of hydration free energies calculated using an integral equation theory of molecular liquids, the 3D reference interaction site model. A strong linear correlation is observed between the difference of the experimental and (uncorrected) calculated hydration free energies and the calculated partial molar volume for a data set of 185 neutral organic molecules from different chemical classes. By using the partial molar volume as a linear empirical correction to the calculated hydration free energy, we obtain predictions of hydration free energies in excellent agreement with experiment (R = 0.94, σ = 0.99 kcal mol -1 for a test set of 120 organic molecules). (fast track communication)

  8. Reference gene selection for molecular studies of dormancy in wild oat (Avena fatua L. caryopses by RT-qPCR method.

    Directory of Open Access Journals (Sweden)

    Izabela Ruduś

    Full Text Available Molecular studies of primary and secondary dormancy in Avena fatua L., a serious weed of cereal and other crops, are intended to reveal the species-specific details of underlying molecular mechanisms which in turn may be useable in weed management. Among others, quantitative real-time PCR (RT-qPCR data of comparative gene expression analysis may give some insight into the involvement of particular wild oat genes in dormancy release, maintenance or induction by unfavorable conditions. To assure obtaining biologically significant results using this method, the expression stability of selected candidate reference genes in different data subsets was evaluated using four statistical algorithms i.e. geNorm, NormFinder, Best Keeper and ΔCt method. Although some discrepancies in their ranking outputs were noticed, evidently two ubiquitin-conjugating enzyme homologs, AfUBC1 and AfUBC2, as well as one homolog of glyceraldehyde 3-phosphate dehydrogenase AfGAPDH1 and TATA-binding protein AfTBP2 appeared as more stably expressed than AfEF1a (translation elongation factor 1α, AfGAPDH2 or the least stable α-tubulin homolog AfTUA1 in caryopses and seedlings of A. fatua. Gene expression analysis of a dormancy-related wild oat transcription factor VIVIPAROUS1 (AfVP1 allowed for a validation of candidate reference genes performance. Based on the obtained results it can be recommended that the normalization factor calculated as a geometric mean of Cq values of AfUBC1, AfUBC2 and AfGAPDH1 would be optimal for RT-qPCR results normalization in the experiments comprising A. fatua caryopses of different dormancy status.

  9. Reference gene selection for molecular studies of dormancy in wild oat (Avena fatua L.) caryopses by RT-qPCR method.

    Science.gov (United States)

    Ruduś, Izabela; Kępczyński, Jan

    2018-01-01

    Molecular studies of primary and secondary dormancy in Avena fatua L., a serious weed of cereal and other crops, are intended to reveal the species-specific details of underlying molecular mechanisms which in turn may be useable in weed management. Among others, quantitative real-time PCR (RT-qPCR) data of comparative gene expression analysis may give some insight into the involvement of particular wild oat genes in dormancy release, maintenance or induction by unfavorable conditions. To assure obtaining biologically significant results using this method, the expression stability of selected candidate reference genes in different data subsets was evaluated using four statistical algorithms i.e. geNorm, NormFinder, Best Keeper and ΔCt method. Although some discrepancies in their ranking outputs were noticed, evidently two ubiquitin-conjugating enzyme homologs, AfUBC1 and AfUBC2, as well as one homolog of glyceraldehyde 3-phosphate dehydrogenase AfGAPDH1 and TATA-binding protein AfTBP2 appeared as more stably expressed than AfEF1a (translation elongation factor 1α), AfGAPDH2 or the least stable α-tubulin homolog AfTUA1 in caryopses and seedlings of A. fatua. Gene expression analysis of a dormancy-related wild oat transcription factor VIVIPAROUS1 (AfVP1) allowed for a validation of candidate reference genes performance. Based on the obtained results it can be recommended that the normalization factor calculated as a geometric mean of Cq values of AfUBC1, AfUBC2 and AfGAPDH1 would be optimal for RT-qPCR results normalization in the experiments comprising A. fatua caryopses of different dormancy status.

  10. Advancing development of a limit reference point estimator for sea turtles, and evaluating methods for applying local management to highly migratory species

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — SWFSC is developing tools for estimation of limit reference points for marine turtles. These tools are being applied initially to estimate a limit reference point...

  11. 同一控制下吸收合并会计处理方法探讨%The Discussion of Accounting Methods of Consolidation by Merger Under the Common Control

    Institute of Scientific and Technical Information of China (English)

    许仁青; 潘施情

    2012-01-01

    本文讨论了同一控制下吸收合并会计处理的两种方法,指出了二者的本质区别在于“是否保留被合并企业的留存收益”,并提出了自己的看法.%The paper discusses two accounting methods of consolidation by merger under the common control . It points out that the essential difference between them is whether the combined enterprise' s retained earnings should be retained and puts forward its own views.

  12. Estimation of biological variation and reference change value of glycated hemoglobin (HbA(1c)) when two analytical methods are used.

    Science.gov (United States)

    Ucar, Fatma; Erden, Gonul; Ginis, Zeynep; Ozturk, Gulfer; Sezer, Sevilay; Gurler, Mukaddes; Guneyk, Ahmet

    2013-10-01

    Available data on biological variation of HbA1c revealed marked heterogeneity. We therefore investigated and estimated the components of biological variation for HbA1c in a group of healthy individuals by applying a recommended and strictly designed study protocol using two different assay methods. Each month, samples were derived on the same day, for three months. Four EDTA whole blood samples were collected from each individual (20 women, 9 men; 20-45 years of age) and stored at -80°C until analysis. HbA1c values were measured by both high performance liquid chromatography (HPLC) (Shimadzu, Prominence, Japan) and boronate affinity chromatography methods (Trinity Biotech, Premier Hb9210, Ireland). All samples were assayed in duplicate in a single batch for each assay method. Estimations were calculated according to the formulas described by Fraser and Harris. The within subject (CV(I))-between subject (CV(G)) biological variations were 1.17% and 5.58%, respectively for HPLC. The calculated CV(I) and CV(G) were 2.15% and 4.03%, respectively for boronate affinity chromatography. Reference change value (RCV) for HPLC and boronate affinity chromatography was 5.4% and 10.4% respectively and individuality index of HbA(1c) was 0.35 and 0.93 respectively. This study for the first time described the components of biological variation for HbA1c in healthy individuals by two different assay methods. Obtained findings showed that the difference between CV(A) values of the methods might considerably affect RCV. These data regarding biological variation of HbA(1c) could be useful for a better evaluation of HbA(1c) test results in clinical interpretation. Copyright © 2013 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  13. THE APPLICABILITY OF SMALL GROUP DISCUSSION IN ENGLISH READING CLASS

    Directory of Open Access Journals (Sweden)

    Kurniawan Yudhi Nugroho

    2017-04-01

    Full Text Available Success of learning is not only a matter of using an appropriate teaching resources, instead, the interference of teaching method is found to be essential to determine the students’ learning achievement. Teacher as a captain of class has the right to choose type of method used in the classroom for sake of students’ improvement. This study was designed as an attempt to help Master Students from a well established private university improve their reading comprehension skill through small group discussion. This study was participated by 30 students, later divided into two classes and served differently as an experimental group for the class A and a control group for the class B. Referring to the final data analysis of the study, it is found that there is an improving learning achievement in the experimental group, indicated by higher performance of posttest (20.333 than the pretest. Apart from this, further analysis was also conducted to find out whether or not small group discussion was able to show better performance than another teaching method applied in another different class. Based on the result of statistical calculation, it shows that small group discussion got better result 12.334 than that of another group. As a result, some suggestions were made by referring to result of the study.

  14. A comparative study on vaccination pain in the methods of massage therapy and mothers' breast feeding during injection of infants referring to Navabsafavi Health Care Center in Isfahan.

    Science.gov (United States)

    Esfahani, Mitra Savabi; Sheykhi, Sanaz; Abdeyazdan, Zahra; Jodakee, Mohamadreza; Boroumandfar, Khadijeh

    2013-11-01

    Vaccination is one of the most common painful procedures in infants. The irreversible consequences due to pain experiences in infants are enormous. Breast feeding and massage therapy methods are the non-drug methods of pain relief. Therefore, this research aimed to compare the vaccination-related pain in infants who underwent massage therapy or breast feeding during injection. This study is a randomized clinical trial. Ninety-six infants were allocated randomly and systematically to three groups (breast feeding, massage, and control groups). The study population comprised all infants, accompanied by their mothers, referring to one of the health centers in Isfahan for vaccination of hepatitis B and DPT at 6 months of age and for MMR at 12 months of age. Data gathering was done using questionnaire and checklist [neonatal infant pain scale (NIPS)]. Data analysis was done using descriptive and inferential statistical methods with SPSS software. Findings of the study showed that the three groups had no statistically significant difference in terms of demographic characteristics (P > 0/05). The mean pain scores in the breast feeding group, massage therapy, and control group were 3.4, 3.9, and 4.8, respectively (P massage therapy and breast feeding (P = 0.041), breast feeding group and control (P massage therapy and control groups (P = 0.002) were statistically significant. Considering the results of the study, it seems that breast feeding during vaccination has more analgesic effect than massage therapy. Therefore, it is suggested as a noninvasive, safe, and accessible method without any side effects for reducing vaccination-related pain.

  15. Nickel quantification in serum by a validated sector-field inductively coupled plasma mass spectrometry method: Assessment of tentative reference values for an Italian population.

    Science.gov (United States)

    Bocca, Beatrice; Forte, Giovanni; Ronchi, Anna; Gaggeri, Raffaella; Alimonti, Alessandro; Minoia, Claudio

    2006-01-01

    The daily exposure to Ni from food, industrial processes, jewellery and coins makes the determination of Ni in human serum an important way to monitor the health status in non-occupationally exposed subjects. To this end, a method based on sector-field inductively coupled plasma mass spectrometry was developed and validated. The limits of detection (LoD) and quantification (LoQ), sensitivity, linearity range, trueness, repeatability, within-laboratory reproducibility and robustness were the considered issues of the validation process. The uncertainty associated with the measurements was also calculated, according to the Eurachem/Citac Guide. The method LoD and LoQ were 0.03 and 0.09 ng mL(-1), linearity was over two order of magnitude, trueness was -3.57%, and the repeatability and reproducibility showed relative standard deviations equal to 4.56% and 6.52%, respectively. The relative expanded uncertainty was 21.8% at the Ni levels found in the general population. The tentative reference value for serum Ni was 0.466 +/- 0.160 ng mL(-1) with a related interval between 0.226 and 1.026 ng mL(-1). Copyright 2006 John Wiley & Sons, Ltd.

  16. Reference costs of electricity

    International Nuclear Information System (INIS)

    Terraz, N.

    1997-01-01

    The calculation of electric power production reference costs is used in France, even in the present case of over-capacity, for comparing the relative interest of the various means of power generation (nuclear plants, coal plants, hydroelectricity, gas combined cycles, etc.) and as an aid for future investment decisions. Reference costs show a sharp decrease between 1993 and 1997 due to advancements in nuclear plant operating ability and fossil fuel price decrease. Actuarial rates, plant service life, fuel costs and exchange rates are important parameters. The various costs from the research stage to the waste processing stages are discussed and the reference costs of the various power generation systems are presented and compared together with their competitiveness; the future of wind energy and cogeneration and the prospective of the renewal of nuclear plants at the 2010 horizon are also addressed

  17. 40 CFR Table E-1 to Subpart E of... - Summary of Test Requirements for Reference and Class I Equivalent Methods for PM2.5 and PM10-2.5

    Science.gov (United States)

    2010-07-01

    ... Reference and Class I Equivalent Methods for PM2.5 and PM10-2.5 E Table E-1 to Subpart E of Part 53..., Subpt. E, Table E-1 Table E-1 to Subpart E of Part 53—Summary of Test Requirements for Reference and Class I Equivalent Methods for PM2.5 and PM10-2.5 Subpart E procedure Performance test Performance...

  18. Summaries of discussion groups and closeout

    International Nuclear Information System (INIS)

    1998-01-01

    The Beam Instrumentation Workshop registrants selected the following topics for group discussions: Commercial technology and beam instrumentation, 4th generation light source instrumentation, feedback systems, beam loss monitors, calibration methods, high resolution and highly stable BPM methods, challenges in beam profiling. Summaries of these discussion sessions are listed in the article that follows

  19. Program reference schedule baseline

    International Nuclear Information System (INIS)

    1986-07-01

    This Program Reference Schedule Baseline (PRSB) provides the baseline Program-level milestones and associated schedules for the Civilian Radioactive Waste Management Program. It integrates all Program-level schedule-related activities. This schedule baseline will be used by the Director, Office of Civilian Radioactive Waste Management (OCRWM), and his staff to monitor compliance with Program objectives. Chapter 1 includes brief discussions concerning the relationship of the PRSB to the Program Reference Cost Baseline (PRCB), the Mission Plan, the Project Decision Schedule, the Total System Life Cycle Cost report, the Program Management Information System report, the Program Milestone Review, annual budget preparation, and system element plans. Chapter 2 includes the identification of all Level 0, or Program-level, milestones, while Chapter 3 presents and discusses the critical path schedules that correspond to those Level 0 milestones

  20. Quantum frames of reference

    International Nuclear Information System (INIS)

    Kaufherr, T.

    1981-01-01

    The idea that only relative variables have physical meaning came to be known as Mach's principle. Carrying over this idea to quantum theory, has led to the consideration of finite mass, macroscopic reference frames, relative to which all physical quantities are measured. During the process of measurement, a finite mass observer receives a kickback, and this reaction of the measuring device is not negligible in quantum theory because of the quantization of the action. Hence, the observer himself has to be included in the system that is being considered. Using this as the starting point, a number of thought experiments involving finite mass observers is discussed which have quantum uncertainties in their time or in their position. These thought experiments serve to elucidate in a qualitative way some of the difficulties involved, as well as pointing out a direction to take in seeking solutions to them. When the discussion is extended to include more than one observer, the question of the covariance of the theory immediately arises. Because none of the frames of reference should be preferred, the theory should be covariant. This demand expresses an equivalence principle which here is extended to include reference frames which are in quantum uncertainties relative to each other. Formulating the problem in terms of canonical variables, the ensueing free Hamiltonian contains vector and scalar potentials which represent the kick that the reference frame receives during measurement. These are essentially gravitational type potentials, resulting, as it were, from the extension of the equivalence principle into the quantum domain

  1. Establishment of Traceability of Reference Grade Hydrometers at National Physical Laboratory, India (npli)

    Science.gov (United States)

    Kumar, Anil; Kumar, Harish; Mandal, Goutam; Das, M. B.; Sharma, D. C.

    The present paper discusses the establishment of traceability of reference grade hydrometers at National Physical Laboratory, India (NPLI). The reference grade hydrometers are calibrated and traceable to the primary solid density standard. The calibration has been done according to standard procedure based on Cuckow's Method and the reference grade hydrometers calibrated covers a wide range. The uncertainty of the reference grade hydrometers has been computed and corrections are also calculated for the scale readings, at which observations are taken.

  2. Photovoltaic yield: correction method for the mismatch between the solar spectrum and the reference ASTMG AM1.5G spectrum

    Directory of Open Access Journals (Sweden)

    Mambrini Thomas

    2015-01-01

    Full Text Available We propose a method for a spectral correction of the predicted PV yield and we show the importance of the spectral mismatch on the solar cell. Indeed, currently predicted PV yield are made considering solar irradiation, ambient temperature, incidence angle and partially (or not the solar spectrum. However, the solar spectrum is not always the same. It varies depending on the site location, atmospheric conditions, time of the day...This may impact the photovoltaic solar cells differently according to their technology (crystalline Silicon, thin film, multi-junctions... This paper presents a method for calculating the correction of the short-circuit current of a photovoltaic cell due to the mismatch of the solar spectrum with the reference ASTM AM1.5G spectrum, for a specific site, throughout the year, using monthly data of AERONET (AErosol RObotic NETwork established by NASA and CNRS and the model SMARTS (simple model for atmospheric transmission of sunshine developed by the NREL. We applied this correction method on the site of Palaiseau (France, 48.7°N, 2.2°E, 156 m, close to our laboratory, just for comparison and the example of Blida (Algeria, 36°N, 2°E, 230 m is given for one year. This example illustrates the importance of this spectral correction to better estimate the photovoltaic yield. To be more precise, instead of modeling the solar spectral distribution, one can measure it with a spectro-radiometer, and then, derive the spectral mismatch correction. Some of our typical measurements are presented in this paper.

  3. Estimation of Completeness of Cancer Registration for Patients Referred to Shiraz Selected Centers through a Two Source Capture Re-capture Method, 2009 Data.

    Science.gov (United States)

    Sharifian, Roxana; SedaghatNia, Mohammad Hossein; Nematolahi, Mohtram; Zare, Najaf; Barzegari, Saeed

    2015-01-01

    Cancer has important social consequences with cancer registration as the basis of moving towards prevention. The present study aimed to estimate the completeness of registration of the ten most common cancers in patients referred to selected hospitals in Shiraz, Iran by using capture-recapture method. This cross-sectional analytical study was performed in 2014 based on the data of 2009, on a total of 4,388 registered cancer patients. After cleaning data from two sources, using capture-recapture common findings were identified. Then, the percentage of the completeness of cancer registration was estimated using Chapman and Chao methods. Finally, the effects of demographic and treatment variables on the completeness of cancer registration were investigated. The results showed that the percentages of completeness of cancer registration in the selected hospitals of Shiraz were 58.6% and 58.4%, and influenced by different variables. The age group between 40-49 years old was the highest represented and for the age group under 20 years old was the lowest for cancer registration. Breast cancer had the highest registration level and after that, thyroid and lung cancers, while colorectal cancer had the lowest registration level. According to the results, the number of cancers registered was very few and it seems that factors like inadequate knowledge of some doctors, imprecise diagnosis about the types of cancer, incorrectly filled out medical documents, and lack of sufficient accuracy in recording data on the computer cause errors and defects in cancer registration. This suggests a necessity to educate and teach doctors and other medical workers about the methods of documenting information related to cancer and also conduct additional measures to improve the cancer registration system.

  4. Electrical engineer's reference book

    CERN Document Server

    Laughton, M A

    1985-01-01

    Electrical Engineer's Reference Book, Fourteenth Edition focuses on electrical engineering. The book first discusses units, mathematics, and physical quantities, including the international unit system, physical properties, and electricity. The text also looks at network and control systems analysis. The book examines materials used in electrical engineering. Topics include conducting materials, superconductors, silicon, insulating materials, electrical steels, and soft irons and relay steels. The text underscores electrical metrology and instrumentation, steam-generating plants, turbines

  5. Home birth and barriers to referring women with obstetric complications to hospitals: a mixed-methods study in Zahedan, southeastern Iran

    Directory of Open Access Journals (Sweden)

    Ghazi Tabatabaie Mahmoud

    2012-03-01

    Full Text Available Abstract Background One factor that contributes to high maternal mortality in developing countries is the delayed use of Emergency Obstetric-Care (EmOC facilities. The objective of this study was to determine the factors that hinder midwives and parturient women from using hospitals when complications occur during home birth in Sistan and Baluchestan province, Iran, where 23% of all deliveries take place in non- hospital settings. Methods In the study and data management, a mixed-methods approach was used. In the quantitative phase, we compared the existing health-sector data with World Health Organization (WHO standards for the availability and use of EmOC services. The qualitative phase included collection and analysis of interviews with midwives and traditional birth attendants and twenty-one in-depth interviews with mothers. The data collected in this phase were managed according to the principles of qualitative data analysis. Results The findings demonstrate that three distinct factors lead to indecisiveness and delay in the use of EmOC by the midwives and mothers studied. Socio-cultural and familial reasons compel some women to choose to give birth at home and to hesitate seeking professional emergency care for delivery complications. Apprehension about being insulted by physicians, the necessity of protecting their professional integrity in front of patients and an inability to persuade their patients lead to an over-insistence by midwives on completing deliveries at the mothers' homes and a reluctance to refer their patients to hospitals. The low quality and expense of EmOC and the mothers' lack of health insurance also contribute to delays in referral. Conclusions Women who choose to give birth at home accept the risk that complications may arise. Training midwives and persuading mothers and significant others who make decisions about the value of referring women to hospitals at the onset of life-threatening complications are central

  6. Home birth and barriers to referring women with obstetric complications to hospitals: a mixed-methods study in Zahedan, southeastern Iran

    Science.gov (United States)

    2012-01-01

    Background One factor that contributes to high maternal mortality in developing countries is the delayed use of Emergency Obstetric-Care (EmOC) facilities. The objective of this study was to determine the factors that hinder midwives and parturient women from using hospitals when complications occur during home birth in Sistan and Baluchestan province, Iran, where 23% of all deliveries take place in non- hospital settings. Methods In the study and data management, a mixed-methods approach was used. In the quantitative phase, we compared the existing health-sector data with World Health Organization (WHO) standards for the availability and use of EmOC services. The qualitative phase included collection and analysis of interviews with midwives and traditional birth attendants and twenty-one in-depth interviews with mothers. The data collected in this phase were managed according to the principles of qualitative data analysis. Results The findings demonstrate that three distinct factors lead to indecisiveness and delay in the use of EmOC by the midwives and mothers studied. Socio-cultural and familial reasons compel some women to choose to give birth at home and to hesitate seeking professional emergency care for delivery complications. Apprehension about being insulted by physicians, the necessity of protecting their professional integrity in front of patients and an inability to persuade their patients lead to an over-insistence by midwives on completing deliveries at the mothers' homes and a reluctance to refer their patients to hospitals. The low quality and expense of EmOC and the mothers' lack of health insurance also contribute to delays in referral. Conclusions Women who choose to give birth at home accept the risk that complications may arise. Training midwives and persuading mothers and significant others who make decisions about the value of referring women to hospitals at the onset of life-threatening complications are central factors to increasing the use

  7. The effects of using concept mapping as an artifact to engender metacognitive thinking in first-year medical students' problem-based learning discussions: A mixed-methods investigation

    Science.gov (United States)

    Shoop, Glenda Hostetter

    Attention in medical education is turning toward instruction that not only focuses on knowledge acquisition, but on developing the medical students' clinical problem-solving skills, and their ability to critically think through complex diseases. Metacognition is regarded as an important consideration in how we teach medical students these higher-order, critical thinking skills. This study used a mixed-methods research design to investigate if concept mapping as an artifact may engender metacognitive thinking in the medical student population. Specifically the purpose of the study is twofold: (1) to determine if concept mapping, functioning as an artifact during problem-based learning, improves learning as measured by scores on test questions; and (2) to explore if the process of concept mapping alters the problem-based learning intragroup discussion in ways that show medical students are engaged in metacognitive thinking. The results showed that students in the problem-based learning concept-mapping groups used more metacognitive thinking patterns than those in the problem-based learning discussion-only group, particularly in the monitoring component. These groups also engaged in a higher level of cognitive thinking associated with reasoning through mechanisms-of-action and breaking down complex biochemical and physiologic principals. The students disclosed in focus-group interviews that concept mapping was beneficial to help them understand how discrete pieces of information fit together in a bigger structure of knowledge. They also stated that concept mapping gave them some time to think through these concepts in a larger conceptual framework. There was no significant difference in the exam-question scores between the problem-based learning concept-mapping groups and the problem-based learning discussion-only group.

  8. Moving Reference to the Web.

    Science.gov (United States)

    McGlamery, Susan; Coffman, Steve

    2000-01-01

    Explores the possibility of using Web contact center software to offer reference assistance to remote users. Discusses a project by the Metropolitan Cooperative Library System/Santiago Library System consortium to test contact center software and to develop a virtual reference network. (Author/LRW)

  9. "In Your Face" Reference Service.

    Science.gov (United States)

    Lipow, Anne Grodzins

    1999-01-01

    Discusses changes in library reference service that have occurred with growing Internet use. Topics include the human factor that is still needed; the nature of reference questions; the goal of user self-sufficiency; the invisible nature of much of librarians' work; and providing real-time, interactive point-of-need service to remote users. (LRW)

  10. Technostress and the Reference Librarian.

    Science.gov (United States)

    Kupersmith, John

    1992-01-01

    Defines "technostress" as the stress experienced by reference librarians who must constantly deal with the demands of new information technology and the changes they produce in the work place. Discussion includes suggested ways in which both organizations and individuals can work to reduce stress. (27 references) (LAE)

  11. Reference Services: A Handmaid's Tale.

    Science.gov (United States)

    Beck, Clare

    1991-01-01

    Discussion of problems in library reference services focuses on the influence of gender roles. A historical overview of gender roles in the development of American librarianship is presented that highlights stereotyped views of and attitudes toward women, which the author suggests still have influences on librarianship today. (17 references) (LRW)

  12. Analysis of SMELS and reference materials for validation of the k0-based internal monostandard NAA method using in-situ detection efficiency

    Science.gov (United States)

    Acharya, R.; Swain, K. K.; Reddy, A. V. R.

    2010-10-01

    Three synthetic multielement standards (SMELS I, II and III) and two reference materials (RMs), SL-3 and Soil-7 of IAEA were analyzed for validation of the k0-based internal monostandard neutron activation analysis (IM-NAA) method utilizing in-situ relative detection efficiency. The internal monostandards used in SMELS and RMs were Au and Sc, respectively. The samples were irradiated in Apsara and Dhruva reactors, BARC and radioactive assay was carried out using a 40% relative efficiency HPGe detector coupled to an 8 k MCA. Concentrations of 23 elements were determined in both SMELS and RMs. In the case of RMs, concentrations of a few elements, whose certified values are not available, could also be determined. The % deviations for the elements determined in SMELS with respect to the assigned values and RMs with respect to certified values were within ±8%. The Z-score values at 95% confidence level for most of the elements in both the materials were within ±1.

  13. Optimization of the reference region method for dual pharmacokinetic modeling using Gd-DTPA/MRI and (18) F-FDG/PET.

    Science.gov (United States)

    Poulin, Éric; Lebel, Réjean; Croteau, Étienne; Blanchette, Marie; Tremblay, Luc; Lecomte, Roger; Bentourkia, M'hamed; Lepage, Martin

    2015-02-01

    The combination of MRI and positron emission tomography (PET) offers new possibilities for the development of novel methodologies. In pharmacokinetic image analysis, the blood concentration of the imaging compound as a function of time, [i.e., the arterial input function (AIF)] is required for MRI and PET. In this study, we tested whether an AIF extracted from a reference region (RR) in MRI can be used as a surrogate for the manually sampled (18) F-FDG AIF for pharmacokinetic modeling. An MRI contrast agent, gadolinium-diethylenetriaminepentaacetic acid (Gd-DTPA) and a radiotracer, (18) F-fluorodeoxyglucose ((18) F-FDG), were simultaneously injected in a F98 glioblastoma rat model. A correction to the RR AIF for Gd-DTPA is proposed to adequately represent the manually sampled AIF. A previously published conversion method was applied to convert this AIF into a (18) F-FDG AIF. The tumor metabolic rate of glucose (TMRGlc) calculated with the manually sampled (18) F-FDG AIF, the (18) F-FDG AIF converted from the RR AIF and the (18) F-FDG AIF converted from the corrected RR AIF were found not statistically different (P>0.05). An AIF derived from an RR in MRI can be accurately converted into a (18) F-FDG AIF and used in PET pharmacokinetic modeling. © 2014 Wiley Periodicals, Inc.

  14. Reference Japanese man

    International Nuclear Information System (INIS)

    Tanaka, Giichiro

    1985-01-01

    To make real and accurate dose assessment method so far, it is necessitated to provide ''Reference Japanese Man'' based on anotomical, physiological and biochemical data of Japanese people instead of the Reference Man presented in ICRP Publications 23 and 30. This review describes present status of researched for the purpose of establishing of Reference Japanese Man. The Reference Japanese Man is defined as a male or female adult who lives in Japan with a Japanese life-style and food custom. His stature and body weight, and the other data was decided as mean values of male or female people of Japan. As for food custom, Japanese people take significantly smaller amount of meat and milk products than Western people, while larger intake amount of cereals and marine products such as fish or seaweeds. Weight of organs is a principal factor for internal dose assessment and mean values for living Japanese adult has been investigated and the value employable for dose assessment for organs and tissues are shown. To employ these values of Reference Japanese Man, it should be taken into account of age. Metabolic parameters should also be considered. Iodine metabolism in Japanese is quite different from that of Western people. The above-mentioned data are now tentatively employing in modification of table of MIRD method and others. (Takagi, S.)

  15. 40 CFR Appendix J to Part 50 - Reference Method for the Determination of Particulate Matter as PM10 in the Atmosphere

    Science.gov (United States)

    2010-07-01

    ... samplers. The user's goals in sampling determine the relative importance of various filter characteristics... shall have an associated operation or instruction manual as required by part 53 of this chapter which... manual and Reference 2 for specific guidance on calibration. Reference 14 provides additional information...

  16. Fully automatic and reference-marker-free image stitching method for full-spine and full-leg imaging with computed radiography

    Science.gov (United States)

    Wang, Xiaohui; Foos, David H.; Doran, James; Rogers, Michael K.

    2004-05-01

    Full-leg and full-spine imaging with standard computed radiography (CR) systems requires several cassettes/storage phosphor screens to be placed in a staggered arrangement and exposed simultaneously to achieve an increased imaging area. A method has been developed that can automatically and accurately stitch the acquired sub-images without relying on any external reference markers. It can detect and correct the order, orientation, and overlap arrangement of the subimages for stitching. The automatic determination of the order, orientation, and overlap arrangement of the sub-images consists of (1) constructing a hypothesis list that includes all cassette/screen arrangements, (2) refining hypotheses based on a set of rules derived from imaging physics, (3) correlating each consecutive sub-image pair in each hypothesis and establishing an overall figure-of-merit, (4) selecting the hypothesis of maximum figure-of-merit. The stitching process requires the CR reader to over scan each CR screen so that the screen edges are completely visible in the acquired sub-images. The rotational displacement and vertical displacement between two consecutive sub-images are calculated by matching the orientation and location of the screen edge in the front image and its corresponding shadow in the back image. The horizontal displacement is estimated by maximizing the correlation function between the two image sections in the overlap region. Accordingly, the two images are stitched together. This process is repeated for the newly stitched composite image and the next consecutive sub-image until a full-image composite is created. The method has been evaluated in both phantom experiments and clinical studies. The standard deviation of image misregistration is below one image pixel.

  17. Kinetic parameters of the GUINEVERE reference configuration in VENUS-F reactor obtained from a pile noise experiment using Rossi and Feynman methods

    Energy Technology Data Exchange (ETDEWEB)

    Geslot, Benoit; Pepino, Alexandra; Blaise, Patrick; Mellier, Frederic [CEA, DEN, DER/SPEx, Cadarache, F-13108 St Paul Lez Durance (France); Lecouey, Jean-Luc [LPC Caen, ENSICAEN, Universite de Caen, CNRS/IN2P3, 6 Bd. Marechal Juin 14050 Caen cedex (France); Carta, Mario [ENEA, UTFISST-REANUC, C.R. Casaccia, S.P.040 via Anguillarese 301, 00123 S. Maria Di Galeria, Roma (Italy); Kochetkov, Anatoly; Vittiglio, Guido [SCK.CEN, Belgian Nuclear Research Centre, Boeretang 200, BE-2400, Mol (Belgium); Billebaud, Annick [LPSC, CNRS, IN2P3/UJF/INPG, 53 Avenue des Martyrs, 38026 Grenoble cedex (France)

    2015-07-01

    A pile noise measurement campaign has been conducted by the CEA in the VENUS-F reactor (SCK-CEN, Mol Belgium) in April 2011 in the reference critical configuration of the GUINEVERE experimental program. The experimental setup made it possible to estimate the core kinetic parameters: the prompt neutron decay constant, the delayed neutron fraction and the generation time. A precise assessment of these constants is of prime importance. In particular, the effective delayed neutron fraction is used to normalize and compare calculated reactivities of different subcritical configurations, obtained by modifying either the core layout or the control rods position, with experimental ones deduced from the analysis of measurements. This paper presents results obtained with a CEA-developed time stamping acquisition system. Data were analyzed using Rossi-α and Feynman-α methods. Results were normalized to reactor power using a calibrated fission chamber with a deposit of Np-237. Calculated factors were necessary to the analysis: the Diven factor was computed by the ENEA (Italy) and the power calibration factor by the CNRS/IN2P3/LPC Caen. Results deduced with both methods are consistent with respect to calculated quantities. Recommended values are given by the Rossi-α estimator, that was found to be the most robust. The neutron generation time was found equal to 0.438 ± 0.009 μs and the effective delayed neutron fraction is 765 ± 8 pcm. Discrepancies with the calculated value (722 pcm, calculation from ENEA) are satisfactory: -5.6% for the Rossi-α estimate and -2.7% for the Feynman-α estimate. (authors)

  18. JDBC Pocket Reference

    CERN Document Server

    Bales, Donald

    2003-01-01

    JDBC--the Java Database Connectivity specification--is a complex set of application programming interfaces (APIs) that developers need to understand if they want their Java applications to work with databases. JDBC is so complex that even the most experienced developers need to refresh their memories from time to time on specific methods and details. But, practically speaking, who wants to stop and thumb through a weighty tutorial volume each time a question arises? The answer is the JDBC Pocket Reference, a data-packed quick reference that is both a time-saver and a lifesaver. The JDBC P

  19. The Current Discussion on Men and Masculinities

    Directory of Open Access Journals (Sweden)

    2007-05-01

    Full Text Available In the past gender specific problems were mainly discussed in a female perspective. In the meantime there is a rising attentiveness in the living conditions of men and their coping strategies within critical life events. In this paper an appropriate frame of reference is outlined which can be used in those areas of social work where men are already discovered as a target group with special difficulties and needs.

  20. The Spallation Neutron Source RF Reference System

    CERN Document Server

    Piller, Maurice; Crofford, Mark; Doolittle, Lawrence; Ma, Hengjie

    2005-01-01

    The Spallation Neutron Source (SNS) RF Reference System includes the master oscillator (MO), local oscillator(LO) distribution, and Reference RF distribution systems. Coherent low noise Reference RF signals provide the ability to control the phase relationships between the fields in the front-end and linear accelerator (linac) RF cavity structures. The SNS RF Reference System requirements, implementation details, and performance are discussed.

  1. Estimation of daily reference evapotranspiration (ETo) using artificial intelligence methods: Offering a new approach for lagged ETo data-based modeling

    Science.gov (United States)

    Mehdizadeh, Saeid

    2018-04-01

    Evapotranspiration (ET) is considered as a key factor in hydrological and climatological studies, agricultural water management, irrigation scheduling, etc. It can be directly measured using lysimeters. Moreover, other methods such as empirical equations and artificial intelligence methods can be used to model ET. In the recent years, artificial intelligence methods have been widely utilized to estimate reference evapotranspiration (ETo). In the present study, local and external performances of multivariate adaptive regression splines (MARS) and gene expression programming (GEP) were assessed for estimating daily ETo. For this aim, daily weather data of six stations with different climates in Iran, namely Urmia and Tabriz (semi-arid), Isfahan and Shiraz (arid), Yazd and Zahedan (hyper-arid) were employed during 2000-2014. Two types of input patterns consisting of weather data-based and lagged ETo data-based scenarios were considered to develop the models. Four statistical indicators including root mean square error (RMSE), mean absolute error (MAE), coefficient of determination (R2), and mean absolute percentage error (MAPE) were used to check the accuracy of models. The local performance of models revealed that the MARS and GEP approaches have the capability to estimate daily ETo using the meteorological parameters and the lagged ETo data as inputs. Nevertheless, the MARS had the best performance in the weather data-based scenarios. On the other hand, considerable differences were not observed in the models' accuracy for the lagged ETo data-based scenarios. In the innovation of this study, novel hybrid models were proposed in the lagged ETo data-based scenarios through combination of MARS and GEP models with autoregressive conditional heteroscedasticity (ARCH) time series model. It was concluded that the proposed novel models named MARS-ARCH and GEP-ARCH improved the performance of ETo modeling compared to the single MARS and GEP. In addition, the external

  2. Use of D-T-produced fast neutrons for in vivo body composition analysis: a reference method for nutritional assessment in the elderly

    Energy Technology Data Exchange (ETDEWEB)

    Kehayias, J.J. [USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St., Boston, 02111-1524 MA (United States)

    2004-05-01

    Body composition has become the main outcome of many nutritional intervention studies including osteoporosis, malnutrition, obesity, AIDS, and aging. Traditional indirect body composition methods developed with healthy young adults do not apply to the elderly or diseased. Fast neutron activation (for N and P) and neutron inelastic scattering (for C and O) are used to assess in vivo elements characteristic of specific body compartments. Non-bone phosphorus for muscle is measured by the {sup 31}P(n,{alpha}){sup 28}Al reaction, and nitrogen for protein via the {sup 14}N(n,2n){sup 13}N fast neutron reaction. Inelastic neutron scattering is used to measure total body carbon and oxygen. Body fat is derived from carbon after correcting for contributions from protein, bone, and glycogen. Carbon-to-oxygen ratio (C/O) is used to measure the distribution of fat and lean tissue in the body and to monitor small changes of lean mass. A sealed, D-T neutron generator is used for the production of fast neutrons. Carbon and oxygen mass and their ratio are measured in vivo at a radiation exposure of less than 0.06 mSv. Gamma-ray spectra are collected using large BGO detectors and analyzed for the 4.43 MeV state of carbon and 6.13 MeV state of oxygen, simultaneously with the irradiation. P and N analysis by delayed fast neutron activation is performed by transferring the patient to a shielded room equipped with an array of NaI(Tl) detectors. A combination of measurements makes possible the assessment of the ''quality'' of fat-free mass. The neutron generator system is used to evaluate the efficacy of new treatments, to study mechanisms of lean tissue depletion with aging, and to investigate methods for preserving function and quality of life in the elderly. It is also used as a reference method for the validation of portable instruments of nutritional assessment. (orig.)

  3. Optimized slice-selective 1H NMR experiments combined with highly accurate quantitative 13C NMR using an internal reference method

    Science.gov (United States)

    Jézéquel, Tangi; Silvestre, Virginie; Dinis, Katy; Giraudeau, Patrick; Akoka, Serge

    2018-04-01

    Isotope ratio monitoring by 13C NMR spectrometry (irm-13C NMR) provides the complete 13C intramolecular position-specific composition at natural abundance. It represents a powerful tool to track the (bio)chemical pathway which has led to the synthesis of targeted molecules, since it allows Position-specific Isotope Analysis (PSIA). Due to the very small composition range (which represents the range of variation of the isotopic composition of a given nuclei) of 13C natural abundance values (50‰), irm-13C NMR requires a 1‰ accuracy and thus highly quantitative analysis by 13C NMR. Until now, the conventional strategy to determine the position-specific abundance xi relies on the combination of irm-MS (isotopic ratio monitoring Mass Spectrometry) and 13C quantitative NMR. However this approach presents a serious drawback since it relies on two different techniques and requires to measure separately the signal of all the carbons of the analyzed compound, which is not always possible. To circumvent this constraint, we recently proposed a new methodology to perform 13C isotopic analysis using an internal reference method and relying on NMR only. The method combines a highly quantitative 1H NMR pulse sequence (named DWET) with a 13C isotopic NMR measurement. However, the recently published DWET sequence is unsuited for samples with short T1, which forms a serious limitation for irm-13C NMR experiments where a relaxing agent is added. In this context, we suggest two variants of the DWET called Multi-WET and Profiled-WET, developed and optimized to reach the same accuracy of 1‰ with a better immunity towards T1 variations. Their performance is evaluated on the determination of the 13C isotopic profile of vanillin. Both pulse sequences show a 1‰ accuracy with an increased robustness to pulse miscalibrations compared to the initial DWET method. This constitutes a major advance in the context of irm-13C NMR since it is now possible to perform isotopic analysis with high

  4. Round Table Discussion on EASTWEST

    Directory of Open Access Journals (Sweden)

    Marina Tkacheva

    2017-12-01

    Full Text Available The discussion is focused on various aspects of interrelations between East and West. Its participants discuss the problems of the increasing tourist flows from China and the specific characteristics of Chinese tourists. The future development of tourism in the Baikal region is formulated, and the peculiarities of ethno tourism and its prospects are discussed.

  5. The Comparison Of In-Flight Pitot Static Calibration Method By Using Radio Altimeter As Reference with GPS and Tower Fly By Methods On CN235-100 MPA

    Science.gov (United States)

    Derajat; Hariowibowo, Hindawan

    2018-04-01

    The new proposed In-Flight Pitot Static Calibration Method has been carried out during Development and Qualification of CN235-100 MPA (Military Patrol Aircraft). This method is expected to reduce flight hours, less human resources required, no additional special equipment, simple analysis calculation and finally by using this method it is expected to automatically minimized operational cost. At The Indonesian Aerospace (IAe) Flight Test Center Division, the development and updating of new flight test technique and data analysis method as specially for flight physics test subject are still continued to be developed as long as it safety for flight and give additional value for the industrial side. More than 30 years, Flight Test Data Engineers at The Flight Test center Division work together with the Air Crew (Test Pilots, Co-Pilots, and Flight Test Engineers) to execute the flight test activity with standard procedure for both the existance or development test techniques and test data analysis. In this paper the approximation of mathematical model, data reduction and flight test technique of The In-Flight Pitot Static Calibration by using Radio Altimeter as reference will be described and the test results had been compared with another methods ie. By using Global Position System (GPS) and the traditional method (Tower Fly By Method) which were used previously during this Flight Test Program (Ref. [10]). The flight test data case are using CN235-100 MPA flight test data during development and Qualification Flight Test Program at Cazaux Airport, France, in June-November 2009 (Ref. [2]).

  6. Determination of reference intervals and comparison of venous blood gas parameters using standard and non-standard collection methods in 24 cats.

    Science.gov (United States)

    Bachmann, Karin; Kutter, Annette Pn; Schefer, Rahel Jud; Marly-Voquer, Charlotte; Sigrist, Nadja

    2017-08-01

    Objectives The aim of this study was to determine in-house reference intervals (RIs) for venous blood analysis with the RAPIDPoint 500 blood gas analyser using blood gas syringes (BGSs) and to determine whether immediate analysis of venous blood collected into lithium heparin (LH) tubes can replace anaerobic blood sampling into BGSs. Methods Venous blood was collected from 24 healthy cats and directly transferred into a BGS and an LH tube. The BGS was immediately analysed on the RAPIDPoint 500 followed by the LH tube. The BGSs and LH tubes were compared using paired t-test or Wilcoxon matched-pairs signed-rank test, Bland-Altman and Passing-Bablok analysis. To assess clinical relevance, bias or percentage bias between BGSs and LH tubes was compared with the allowable total error (TEa) recommended for the respective parameter. Results Based on the values obtained from the BGSs, RIs were calculated for the evaluated parameters, including blood gases, electrolytes, glucose and lactate. Values derived from LH tubes showed no significant difference for standard bicarbonate, whole blood base excess, haematocrit, total haemoglobin, sodium, potassium, chloride, glucose and lactate, while pH, partial pressure of carbon dioxide and oxygen, actual bicarbonate, extracellular base excess, ionised calcium and anion gap were significantly different to the samples collected in BGSs ( P glucose and lactate can be made based on blood collected in LH tubes and analysed within 5 mins. For pH, partial pressure of carbon dioxide and oxygen, extracellular base excess, anion gap and ionised calcium the clinically relevant alterations have to be considered if analysed in LH tubes.

  7. Comparison of methods for individualized astronaut organ dosimetry: Morphometry-based phantom library versus body contour autoscaling of a reference phantom

    Science.gov (United States)

    Sands, Michelle M.; Borrego, David; Maynard, Matthew R.; Bahadori, Amir A.; Bolch, Wesley E.

    2017-11-01

    One of the hazards faced by space crew members in low-Earth orbit or in deep space is exposure to ionizing radiation. It has been shown previously that while differences in organ-specific and whole-body risk estimates due to body size variations are small for highly-penetrating galactic cosmic rays, large differences in these quantities can result from exposure to shorter-range trapped proton or solar particle event radiations. For this reason, it is desirable to use morphometrically accurate computational phantoms representing each astronaut for a risk analysis, especially in the case of a solar particle event. An algorithm was developed to automatically sculpt and scale the UF adult male and adult female hybrid reference phantom to the individual outer body contour of a given astronaut. This process begins with the creation of a laser-measured polygon mesh model of the astronaut's body contour. Using the auto-scaling program and selecting several anatomical landmarks, the UF adult male or female phantom is adjusted to match the laser-measured outer body contour of the astronaut. A dosimetry comparison study was conducted to compare the organ dose accuracy of both the autoscaled phantom and that based upon a height-weight matched phantom from the UF/NCI Computational Phantom Library. Monte Carlo methods were used to simulate the environment of the August 1972 and February 1956 solar particle events. Using a series of individual-specific voxel phantoms as a local benchmark standard, autoscaled phantom organ dose estimates were shown to provide a 1% and 10% improvement in organ dose accuracy for a population of females and males, respectively, as compared to organ doses derived from height-weight matched phantoms from the UF/NCI Computational Phantom Library. In addition, this slight improvement in organ dose accuracy from the autoscaled phantoms is accompanied by reduced computer storage requirements and a more rapid method for individualized phantom generation

  8. [Analysis of knee joint injuries of competitive volleyball players in selected sports clubs of Poznan city--biomechanical context. Synthesis--proposal for the usage of physiotherapy methods in the prevention of the discussed injuries].

    Science.gov (United States)

    Dworak, Lechosław B; Rzepnicka, Agata; Wilkosz, Piotr; Szczesny, Łukasz

    2010-01-01

    Volleyball is a source of direct injuries and chronic overloads of the joints, which indirectly results in traumas and permanent dysfunctions. This applies particularly to: knee joints, ankle joints, shoulder joints and small joints of the hand, as well as the joints of the lower spine regions. Each league team should employ a physiotherapist who would be responsible for the implementation of an injury prevention program as well as for choosing the right training loads. The purpose of this study is to analyze the frequency and the type of knee joint injuries occurring in people practicing Volleyball at competitive level as well as to propose the usage of elements of modern physiotherapy in order to prevent these injuries. The tests were performed over a group of 19 volleyball players from Poznan. In order to propose measures that would prevent injuries, the authors carried out a review of modern physiotherapy methods and suggested the implementation of certain therapeutic techniques for the region of the knee joint. RESULT ANALYSIS AND DISCUSSION: As much as 79% of the subjects reported having chronic pain and knee joint injuries in the past. All of them, due to their conditions, declared having used various forms of physiotherapy treatment. It seems that in a professional sports club not only the presence of a massage therapist but first of all a qualified physiotherapist is indispensable.

  9. Mechanical engineer's reference book

    CERN Document Server

    Parrish, A

    1973-01-01

    Mechanical Engineer's Reference Book: 11th Edition presents a comprehensive examination of the use of Systéme International d' Unités (SI) metrication. It discusses the effectiveness of such a system when used in the field of engineering. It addresses the basic concepts involved in thermodynamics and heat transfer. Some of the topics covered in the book are the metallurgy of iron and steel; screw threads and fasteners; hole basis and shaft basis fits; an introduction to geometrical tolerancing; mechanical working of steel; high strength alloy steels; advantages of making components as castings

  10. Discussion on Papers 11 - 13

    International Nuclear Information System (INIS)

    Haws, E.; Matthews, M.E.; Wilson, E.M.; Charles-Jones, S.; Allen, R.F.; Young, R.M.; O'Connor, B.

    1992-01-01

    The discussion covered the following topics: the nature of boulder clay for foundations; navigation through the barrage; the construction of sluice caissons; government subsidies for construction costs; the effect of wave action on river banks; allowances for reflected energy in hydrodynamic models; water quality in impounded pools; sediment deposition. Separate abstracts have been prepared for the three papers under discussion. (UK)

  11. An overview of digital reference services

    OpenAIRE

    Hemnani, Anita

    2009-01-01

    Digital reference service is an emerging trend of traditional reference service. Easily accessible digital reference service has become one of the hallmark of the library and information services. The paper highlights how new visage of traditional reference service is developing as a natural solution to keep pace with comprehensive technological environment. It discusses about the basic concepts, elements of digital reference service and give in detail modes, the advantages, limitations, and...

  12. Emotional discussions reduce memory recall.

    Science.gov (United States)

    Soleti, Emanuela; Wright, Daniel B; Curci, Antonietta

    2017-05-01

    People often discuss events they have seen and these discussions can influence later recollections. We investigated the effects of factual, emotional, and free retelling discussion on memory recollections of individuals who have witnessed an event. Participants were shown a video, made an initial individual recall, participated in one of the three retelling conditions (emotional versus factual versus free) or a control condition, and then recalled the event individually again. Participants in the factual and free retelling conditions reported more items not previously recalled than participants in the control condition did, while the emotional condition did not show the same advantage. Participants in all three retelling conditions failed to report more previously recalled items as compared with the control condition. Finally, a memory conformity effect was observed for all three retelling conditions. These findings suggest that eyewitnesses' discussions may influence the accuracy of subsequent memory reports, especially when these discussions are focused on emotional details and thoughts.

  13. Method for linking a media work to perform an action, involves linking an electronic media work with a reference electronic media work identifier associated with a reference electronic media work using an approximate neighbor search

    DEFF Research Database (Denmark)

    2016-01-01

    A computer-implemented method including the steps of: receiving, by a computer system including at least one computer, a media work uploaded from a first electronic device; receiving, by the computer system from a second electronic device, a tag associated with the media work having a media work...... identifier; storing, by the computer system, the media work identifier and the associated tag; obtaining, by the computer system from a third electronic device, a query related to the associated tag; correlating, by the computer system, the query with associated information related to an action...... to be performed; and providing, from the computer system to the third electronic device, the associated information to be used in performing the action....

  14. Nuclear energy discussion in Switzerland

    International Nuclear Information System (INIS)

    Brupbacher, F.

    1989-01-01

    As regards the subject of nuclear power, Switzerland is no better off than Germany or the Benelux nations. In particular, Swiss people do not have superior insight or more general agreement in their views as to nuclear energy use. With reference to the whole nation, advocates and opponents of nuclear power currently are about equal in number; hence decisions are blocked the same as elsewhere. (orig.) [de

  15. Analysis of Bone Meal (NIST 1486) and Bone Ash (NIST 1400) reference materials by neutron activation method; Analise de materiais de referencia Bone Meal (NIST 1486) e Bone Ash (NIST 1400) pelo metodo de ativacao com neutrons

    Energy Technology Data Exchange (ETDEWEB)

    Takata, Marcelo K.; Saiki, Mitiko [Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil); Borelli, Aurelio [Sao Paulo Univ., SP (Brazil). Faculdade de Medicina

    1999-11-01

    In this work instrumental neutron activation analysis has been applied to determine Ba, ca, Cl, Cr, fe, Mg, Mn, Na, P, Sb, Sc, Sr and Zn in two biological reference materials NIST 1486 Bone Meal and NIST 1400 Bone Ash. The purpose of this work was to evaluate the precision and the accuracy of the results as well as to give a contribution to certificate these materials. Interferences found in the determination of some elements were also discussed. (author) 8 refs., 4 tabs.

  16. Animating Geometry Discussions with Flexigons.

    Science.gov (United States)

    McClintock, Ruth

    1994-01-01

    Presents activities with 10- and 4-straw flexigons, an object created by stringing together lengths of plastic drinking straws with nylon fishing line. Discusses several geometric theorems that can be demonstrated with flexigons. (MKR)

  17. Lunch to discuss IDRC's programming

    International Development Research Centre (IDRC) Digital Library (Canada)

    chantal Taylor

    Page 1. Description: Lunch to discuss IDRC's programming. Date: 2017-02-10. Attendees: 2 (IDRC 1). Location: Ottawa. Total: $79.92. Comments: 2016-2017 Hospitality Expense. Reports for Jean Lebel, President.

  18. LGBT Roundtable Discussion: Meet-up and Mentoring Discussion

    Science.gov (United States)

    2014-03-01

    The LGBT+ Physicists group welcomes those who identify as gender sexual minorities, as LGBTQQIAAP+, or as allies to participate in a round-table discussion on mentoring physicists. The session will provide an opportunity to learn and discuss successful mentoring strategies at different career stages for physicists in all environments, including academia, industry, etc. Attendees are encouraged to attend a social event to follow the panel to continue to network. Allies are especially welcome at this event to learn how to support and mentor LGBT+ physicists.

  19. Discussion on Papers 5 - 7

    International Nuclear Information System (INIS)

    Strongman, C.P.; Jones, R.; Moorhead, H.

    1992-01-01

    The topics raised in discussion included: the performance of the generator sets; the movement of sediments and the effect on beach levels; monitoring near-bed sediments; the erosion of barrage materials by suspended solids; sediment transport models; the accuracy of hydrographic and other surveys; the relative ornithological importance of the estuary with respect to others in the United Kingdom. Separate abstracts were prepared for each of the three papers under discussion. (UK)

  20. Open Education Week Panel Discussion

    OpenAIRE

    Doolittle, Peter; Hart, Heath; Hartman, Greg; Seyam, Mohammed; Walz, Anita R.

    2015-01-01

    Introduction by Julie Speer, Associate Dean for Research & Informatics. Open remarks by Anita Walz, Assessment, Open Education & Online Learning Environments Librarian. Mohammed Seyam discusses the value of openly licensed material as a student, research, and graduate assistant. Heath Hart reflects on his adoption of an open educational resource and a (subscribed) online textbook in, “A Rousing Success and an Unmitigated Disaster.” Greg Hartman discusses his experiences authoring open-source ...

  1. Laser Lights or Dim Bulbs? Evaluating Reference Librarians' Use of Electronic Sources.

    Science.gov (United States)

    Welch, Jeanie M.

    1999-01-01

    Discusses the evaluation of academic library reference librarians' effectiveness in providing services to patrons using electronic sources based on experiences at the University of North Carolina at Charlotte. Topics include core technical competencies for subject specialists and reference desk service; the Internet; and methods of evaluation.…

  2. Traditional methods v. new technologies - dilemmas for dietary assessment in large-scale nutrition surveys and studies: a report following an international panel discussion at the 9th International Conference on Diet and Activity Methods (ICDAM9), Brisbane, 3 September 2015.

    Science.gov (United States)

    Amoutzopoulos, B; Steer, T; Roberts, C; Cade, J E; Boushey, C J; Collins, C E; Trolle, E; de Boer, E J; Ziauddeen, N; van Rossum, C; Buurma, E; Coyle, D; Page, P

    2018-01-01

    The aim of the present paper is to summarise current and future applications of dietary assessment technologies in nutrition surveys in developed countries. It includes the discussion of key points and highlights of subsequent developments from a panel discussion to address strengths and weaknesses of traditional dietary assessment methods (food records, FFQ, 24 h recalls, diet history with interviewer-assisted data collection) v. new technology-based dietary assessment methods (web-based and mobile device applications). The panel discussion 'Traditional methods v. new technologies: dilemmas for dietary assessment in population surveys', was held at the 9th International Conference on Diet and Activity Methods (ICDAM9), Brisbane, September 2015. Despite respondent and researcher burden, traditional methods have been most commonly used in nutrition surveys. However, dietary assessment technologies offer potential advantages including faster data processing and better data quality. This is a fast-moving field and there is evidence of increasing demand for the use of new technologies amongst the general public and researchers. There is a need for research and investment to support efforts being made to facilitate the inclusion of new technologies for rapid, accurate and representative data.

  3. Comparison of six methods of segmentation of tumor volume on the {sup 18}F-F.D.G. PET scan with reference histological volume in non small cell bronchopulmonary cancers; Comparaison de six methodes de segmentation du volume tumoral sur la {sup 18}F-FDG TEP-TDM avec le volume de reference anatomopathologique dans les cancers bronchopulmonaires non a petites cellules

    Energy Technology Data Exchange (ETDEWEB)

    Venel, Y.; Garhi, H.; Baulieu, J.L.; Prunier-Aesch, C. [CHRU de Tours-Bretonneau, Service de Medecine Nucleaire, 37 - Tours (France); Muret, A. de [CHRU de Tours-Bretonneau, Service de Radiotherapie, 37 - Tours (France); Barillot, I. [CHRU de Tours-Bretonneau, Service d' Anatomopathologie, 37 - Tours (France)

    2008-06-15

    The {sup 18}F-F.D.G. PET has demonstrated its importance in oncology, for initial extension and efficacy of anti tumoral therapeutics. Several studies have attempted to prove its utility to define tumoral volumes for conformational radiotherapy in non small cell lung cancers. Some authors have suggested the use of threshold of tumor intensity uptake with 40 or 50% of maximal intensity. Black et al. have determined contouring with linear regression formula of mean semi-quantitative index of tumor uptake (standard uptake value): SUV{sub threshold} = 0.307 Sub{sub average} + 0.588. Nestle et al. have taken into account the background noise intensity and mean intensity of the tumor: I{sub threshold} = {beta} I{sub average} +I{sub noise} with {beta} 0.15. Our study was done in collaboration with Inserm U618 team and has compared volumes defined on PET scan defined according to different methods based on intensity or S.U.V. to the tumour volume determined on CT scan by radio physicist. We have compared those volumes with histological volume that we considered for reference. Four patients have been included. They had {sup 18}F-F.D.G. PET scan followed by complete tumoral removal surgery. Specific histological procedure allowed to define complete size of the tumor in re expanded lung. Comparatively to pathology, the volumes obtained using I{sub max} 40 and I{sub max} 50 are all underestimated. The volumes defined by Black's et al. method are under evaluated for the two largest tumours (15.8% to 22%) and overestimated for the two smallest ones (17.9 to 82.9%). Nestle's et al. method, using {beta} = 0.15, correctly estimates two tumor volumes over 2 cm, but overestimates the two small tumors (79.6 to 124%). Finally, the corrected Nestle's et al. formula (using {beta} = 0.264) overestimates three tumours. Volumes defined on CT scan by radio physicist are correct for one lesion, underestimated for one and overestimated for two other ones (44 and 179.5%). Nestle

  4. Improving English Speaking Ability Through Classroom Discussion

    OpenAIRE

    Afrizal, M

    2015-01-01

    Speaking is one of important parts in teaching language because it includes one of four basic language skills. Nevertheless, in MA NU BANAT Kudus, the writer found that most of students there still get the difficulties in studying speaking. It may be caused by the method used in teaching English, especially speaking. Classroom Discussion is a method that can be applied in teaching English, especially to improve the ability of speaking. In this method, hopefully, the students get a big opportu...

  5. ``Frames of Reference'' revisited

    Science.gov (United States)

    Steyn-Ross, Alistair; Ivey, Donald G.

    1992-12-01

    The PSSC teaching film, ``Frames of Reference,'' was made in 1960, and was one of the first audio-visual attempts at showing how your physical ``point of view,'' or frame of reference, necessarily alters both your perceptions and your observations of motion. The gentle humor and original demonstrations made a lasting impact on many audiences, and with its recent re-release as part of the AAPT Cinema Classics videodisc it is timely that we should review both the message and the methods of the film. An annotated script and photographs from the film are presented, followed by extension material on rotating frames which teachers may find appropriate for use in their classrooms: constructions, demonstrations, an example, and theory.

  6. Evaluation of reference genes for reverse transcription quantitative real-time PCR (RT-qPCR) studies in Silene vulgaris considering the method of cDNA preparation

    Czech Academy of Sciences Publication Activity Database

    Koloušková, Pavla; Stone, James D.; Štorchová, Helena

    2017-01-01

    Roč. 12, č. 8 (2017), č. článku e0183470. E-ISSN 1932-6203 R&D Projects: GA MŠk(CZ) LH15075; GA ČR(CZ) GA16-09220S Institutional support: RVO:61389030 Keywords : CYTOPLASMIC MALE -STERILITY * SUITABLE REFERENCE GENES * INTERNAL CONTROL GENES Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Plant sciences, botany Impact factor: 2.806, year: 2016

  7. USGS42 and USGS43: Human-hair stable hydrogen and oxygen isotopic reference materials and analytical methods for forensic science and implications for published measurement results

    Science.gov (United States)

    Coplen, T.B.; Qi, H.

    2012-01-01

    Because there are no internationally distributed stable hydrogen and oxygen isotopic reference materials of human hair, the U.S. Geological Survey (USGS) has prepared two such materials, USGS42 and USGS43. These reference materials span values commonly encountered in human hair stable isotope analysis and are isotopically homogeneous at sample sizes larger than 0.2 mg. USGS42 and USGS43 human-hair isotopic reference materials are intended for calibration of δ(2)H and δ(18)O measurements of unknown human hair by quantifying (1) drift with time, (2) mass-dependent isotopic fractionation, and (3) isotope-ratio-scale contraction. While they are intended for measurements of the stable isotopes of hydrogen and oxygen, they also are suitable for measurements of the stable isotopes of carbon, nitrogen, and sulfur in human and mammalian hair. Preliminary isotopic compositions of the non-exchangeable fractions of these materials are USGS42(Tibetan hair)δ(2)H(VSMOW-SLAP) = -78.5 ± 2.3‰ (n = 62) and δ(18)O(VSMOW-SLAP) = +8.56 ± 0.10‰ (n = 18) USGS42(Indian hair)δ(2)H(VSMOW-SLAP) = -50.3 ± 2.8‰ (n = 64) and δ(18)O(VSMOW-SLAP) = +14.11 ± 0.10‰ (n = 18). Using recommended analytical protocols presented herein for δ(2)H(VSMOW-SLAP) and δ(18)O(VSMOW-SLAP) measurements, the least squares fit regression of 11 human hair reference materials is δ(2)H(VSMOW-SLAP) = 6.085δ(2)O(VSMOW-SLAP) - 136.0‰ with an R-square value of 0.95. The δ(2)H difference between the calibrated results of human hair in this investigation and a commonly accepted human-hair relationship is a remarkable 34‰. It is critical that readers pay attention to the δ(2)H(VSMOW-SLAP) and δ(18)O(VSMOW-SLAP) of isotopic reference materials in publications, and they need to adjust the δ(2)H(VSMOW-SLAP) and δ(18)O(VSMOW-SLAP) measurement results of human hair in previous publications, as needed, to ensure all results on are on the same scales.

  8. Discussion on Papers 8 - 10

    International Nuclear Information System (INIS)

    Walker, R.; Wilson, E.A.; Gibson, P.

    1992-01-01

    Questions raised in the discussion are reported. These concerned: the Treasury discount rate for the construction of such a project; the CO 2 benefits of tidal schemes in developing countries; the criteria for deciding the total installed capacity of the scheme; the Government review of the cost-benefit analysis; the benefit arising from the elimination of nitrogen and sulphur oxides; security of supply; carbon tax projections. The only response reported is on the question of criteria for deciding the total installed capacity. Separate abstracts have been prepared on the three papers under discussion. (UK)

  9. General discussion of feasibility study

    International Nuclear Information System (INIS)

    Calori, F.

    1976-01-01

    Fundamentals, objectives and parameters of feasibility studies in the field of nuclear power project planning are discussed in a general way. Technical and economic problems to be considered are pointed out. In special cases, IAEA offers its aid and support. (UA) [de

  10. Helping Students Discuss Race Openly

    Science.gov (United States)

    Landsman, Julie

    2016-01-01

    One way teachers can disrupt inequities is by doing the work to foster discussions in which students talk about race--and racism--honestly together. Teachers also need to be ready to talk with students sensitively when the subject of race comes up spontaneously--in a student's work, connected to events outside school, or in response to a…

  11. Another Discussion about Academic Corruption

    Science.gov (United States)

    Changgeng, Li

    2007-01-01

    Academic corruption is a commonplace matter about which all people are clearly aware. However, people often overlook many hidden or latent manifestations of academic corruption. This article discusses eight of these manifestations: indiscriminate use of the academic team spirit, the proliferation of "word games," deliberate attacks on…

  12. Learning through synchronous electronic discussion

    NARCIS (Netherlands)

    Kanselaar, G.; Veerman, A.L.; Andriessen, J.E.B.

    2000-01-01

    This article reports a study examining university student pairs carrying out an electronic discussion task in a synchronous computer mediated communication (CMC) system (NetMeeting). The purpose of the assignment was to raise students' awareness concerning conceptions that characterise effective

  13. Choice Orientations, Discussions, and Prospects.

    Science.gov (United States)

    Raywid, Mary Anne

    1992-01-01

    Examining the contemporary school choice debate yields arguments that are education, economics, governance, and policy driven. To "break the exclusive franchise," school districts are increasingly sponsoring school operation and education services supplied by multiple sources, and states are discussing sponsorship of schools by entities…

  14. Inertial reference frames and gravitational forces

    International Nuclear Information System (INIS)

    Santavy, I.

    1981-01-01

    The connection between different definitions of inertial, i.e. fundamental, reference frames and the corresponding characterisation of gravitational fields by gravitational forces are considered from the point of view of their possible interpretation in university introductory courses. The introduction of a special class of reference frames, denoted 'mixed reference frames' is proposed and discussed. (author)

  15. Common Frame of Reference and social justice

    NARCIS (Netherlands)

    Hesselink, M.W.; Satyanarayana, R.

    2009-01-01

    The article "Common Frame of Reference and Social Justice" by Martijn W. Hesselink evaluates the Draft Common Frame of Reference (DCFR) of social justice. It discusses the important areas, namely a common frame of Reference in a broad sense, social justice and contract law, private law and

  16. Discussion paper (presented during meeting)

    International Nuclear Information System (INIS)

    Allemand, R.

    1975-01-01

    A method of particle localization for gas chambers (backgammon game method) is presented. The cathode is geometrically cut in such a way that it is possible to establish a simple relation between the signal amplitude on the different parts of the cathode and the position of the nuclear event. The results obtained in the case of x-ray detectors are presented. The application of this method to the localization of neutrons is presently studied [fr

  17. Automation and Job Satisfaction among Reference Librarians.

    Science.gov (United States)

    Whitlatch, Jo Bell

    1991-01-01

    Discussion of job satisfaction and the level of job performance focuses on the effect of automation on job satisfaction among reference librarians. The influence of stress is discussed, a job strain model is explained, and examples of how to design a job to reduce the stress caused by automation are given. (12 references) (LRW)

  18. Summary of presentations and discussions

    International Nuclear Information System (INIS)

    Takeuchi, Mitsuo

    2008-01-01

    In December 2007, the Forum on Stakeholder Confidence discussed its theme entitled 'Link between research, development and demonstration (RD and D) and stakeholder confidence'. It was remarked that regulators need a technical demonstration to aid in evaluating the safety case. Local stakeholders appreciate the opportunity to visualise technological arrangements. In both cases, demonstration adds to confidence in the feasibility of solutions. Some believe there is an important role for analogues in communication with stakeholders, if handled with integrity. To explore and benchmark current practices, it was decided to hold a topical session at the 9. regular meeting of the FSC on 4 June 2008 regarding the use of analogues for confidence building. The session opened with an introductory presentation by the session rapporteur. This incorporated input provided for the purpose by FSC members in cooperation with their country's representative to the NEA RWMC 'Integration Group on the Safety Case'. Three speakers then presented the various uses of analogues by implementers, regulators and scientists to build their own confidence; a fourth speaker dealt with the experience of using natural analogues in public information. The presentations addressed the use of analogues in the field of geological disposal of high-level waste (HLW) and long-lived intermediate level (ILW-LL) radioactive waste. Then the FSC participants split into two working groups for discussion. The outcome of these discussions was reported in plenary on 6 June 2008 and it was agreed to publish proceedings of the session. The present summary, prepared by the session rapporteur with input from the NEA Secretariat, captures the main points heard in the course of the event. It combines data from the formal presentations and remarks made in discussion. The latter represent viewpoints expressed by a group whose primary focus is not natural analogues but rather stakeholder interests. The summary and viewpoints

  19. Qualitative discussion of quantitative radiography

    International Nuclear Information System (INIS)

    Berger, H.; Motz, J.W.

    1975-01-01

    Since radiography yields an image that can be easily related to the tested object, it is superior to many nondestructive testing techniques in revealing the size, shape, and location of certain types of discontinuities. The discussion is limited to a description of the radiographic process, examination of some of the quantitative aspects of radiography, and an outline of some of the new ideas emerging in radiography. The advantages of monoenergetic x-ray radiography and neutron radiography are noted

  20. Four-year prospective study of STAPH-IDENT system and conventional method for reference identification of Staphylococcus, Stomatococcus, and Micrococcus spp..

    Science.gov (United States)

    Rhoden, D L; Miller, J M

    1995-01-01

    A 4-year prospective study compared the accuracy of the STAPH-IDENT system (bioMérieux Vitek, Inc., Hazelwood, Mo.) with that of the reference procedure of the Centers for Disease Control and Prevention for the identification of Staphylococcus species, Stomatococcus mucilaginosus, and Micrococcus species. The study compared the results from 1,106 cultures (500 eye cultures, 217 strains submitted for reference identification, and 389 known stock strains) representing 21 species of the family Micrococcaceae. The overall agreement of genus and species identifications was 81.1%. The percent agreement for the five most common clinical isolates was as follows: Staphylococcus epidermidis, 97.1% (517 isolates); Staphylococcus hominis, 82.5% (57 isolates); Staphylococcus aureus, 77.2% (162 isolates); Staphylococcus haemolyticus, 75.8% (61 isolates); and Staphylococcus warneri, 64.1% (39 isolates). The lowest percent agreement was with Staphylococcus cohnii (11.1%; (9 isolates). Of the 217 isolates sent to the Centers for Disease Control and Prevention for identification, 60.4% (131) were correctly identified by the STAPH-IDENT system. Of these, S. epidermidis accounted for 23.9%, S. aureus accounted for 15.6%, S. warneri accounted for 6.9%, Staphylococcus lugdunensis accounted for 6.5%, S. haemolyticus accounted for 5.5%, and S. hominis accounted for 4.1%. The STAPH-IDENT system did not perform adequately when dealing with commonly encountered organisms and is unsuitable for identifying uncommon isolates. PMID:7699074