methods library search: Topics by WorldWideScience.org

Sample records for methods library search

How Users Search the Library from a Single Search Box

Science.gov (United States)

Lown, Cory; Sierra, Tito; Boyer, Josh

2013-01-01

Academic libraries are turning increasingly to unified search solutions to simplify search and discovery of library resources. Unfortunately, very little research has been published on library user search behavior in single search box environments. This study examines how users search a large public university library using a prominent, single…
Search features of digital libraries

Directory of Open Access Journals (Sweden)

Alastair G. Smith

2000-01-01

Full Text Available Traditional on-line search services such as Dialog, DataStar and Lexis provide a wide range of search features (boolean and proximity operators, truncation, etc. This paper discusses the use of these features for effective searching, and argues that these features are required, regardless of advances in search engine technology. The literature on on-line searching is reviewed, identifying features that searchers find desirable for effective searching. A selective survey of current digital libraries available on the Web was undertaken, identifying which search features are present. The survey indicates that current digital libraries do not implement a wide range of search features. For instance: under half of the examples included controlled vocabulary, under half had proximity searching, only one enabled browsing of term indexes, and none of the digital libraries enable searchers to refine an initial search. Suggestions are made for enhancing the search effectiveness of digital libraries, for instance by: providing a full range of search operators, enabling browsing of search terms, enhancement of records with controlled vocabulary, enabling the refining of initial searches, etc.
Spectrum-to-Spectrum Searching Using a Proteome-wide Spectral Library*

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Yen, Chia-Yu; Houel, Stephane; Ahn, Natalie G.; Old, William M.

2011-01-01

The unambiguous assignment of tandem mass spectra (MS/MS) to peptide sequences remains a key unsolved problem in proteomics. Spectral library search strategies have emerged as a promising alternative for peptide identification, in which MS/MS spectra are directly compared against a reference library of confidently assigned spectra. Two problems relate to library size. First, reference spectral libraries are limited to rediscovery of previously identified peptides and are not applicable to new peptides, because of their incomplete coverage of the human proteome. Second, problems arise when searching a spectral library the size of the entire human proteome. We observed that traditional dot product scoring methods do not scale well with spectral library size, showing reduction in sensitivity when library size is increased. We show that this problem can be addressed by optimizing scoring metrics for spectrum-to-spectrum searches with large spectral libraries. MS/MS spectra for the 1.3 million predicted tryptic peptides in the human proteome are simulated using a kinetic fragmentation model (MassAnalyzer version2.1) to create a proteome-wide simulated spectral library. Searches of the simulated library increase MS/MS assignments by 24% compared with Mascot, when using probabilistic and rank based scoring methods. The proteome-wide coverage of the simulated library leads to 11% increase in unique peptide assignments, compared with parallel searches of a reference spectral library. Further improvement is attained when reference spectra and simulated spectra are combined into a hybrid spectral library, yielding 52% increased MS/MS assignments compared with Mascot searches. Our study demonstrates the advantages of using probabilistic and rank based scores to improve performance of spectrum-to-spectrum search strategies. PMID:21532008
The North Carolina State University Libraries Search Experience: Usability Testing Tabbed Search Interfaces for Academic Libraries

Science.gov (United States)

Teague-Rector, Susan; Ballard, Angela; Pauley, Susan K.

2011-01-01

Creating a learnable, effective, and user-friendly library Web site hinges on providing easy access to search. Designing a search interface for academic libraries can be particularly challenging given the complexity and range of searchable library collections, such as bibliographic databases, electronic journals, and article search silos. Library…
Understanding the foundation: the state of generalist search education in library schools as related to the needs of expert searchers in medical libraries.

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Nicholson, Scott

2005-01-01

The paper explores the current state of generalist search education in library schools and considers that foundation in respect to the Medical Library Association's statement on expert searching. Syllabi from courses with significant searching components were examined from ten of the top library schools, as determined by the U.S. News & World Report rankings. Mixed methods were used, but primarily quantitative bibliometric methods were used. The educational focus in these searching components was on understanding the generalist searching resources and typical users and on performing a reflective search through application of search strategies, controlled vocabulary, and logic appropriate to the search tool. There is a growing emphasis on Web-based search tools and a movement away from traditional set-based searching and toward free-text search strategies. While a core set of authors is used in these courses, no core set of readings is used. While library schools provide a strong foundation, future medical librarians still need to take courses that introduce them to the resources, settings, and users associated with medical libraries. In addition, as more emphasis is placed on Web-based search tools and free-text searching, instructors of the specialist medical informatics courses will need to focus on teaching traditional search methods appropriate for common tools in the medical domain.
Development and experimental test of support vector machines virtual screening method for searching Src inhibitors from large compound libraries

Directory of Open Access Journals (Sweden)

Han Bucong

2012-11-01

Full Text Available Abstract Background Src plays various roles in tumour progression, invasion, metastasis, angiogenesis and survival. It is one of the multiple targets of multi-target kinase inhibitors in clinical uses and trials for the treatment of leukemia and other cancers. These successes and appearances of drug resistance in some patients have raised significant interest and efforts in discovering new Src inhibitors. Various in-silico methods have been used in some of these efforts. It is desirable to explore additional in-silico methods, particularly those capable of searching large compound libraries at high yields and reduced false-hit rates. Results We evaluated support vector machines (SVM as virtual screening tools for searching Src inhibitors from large compound libraries. SVM trained and tested by 1,703 inhibitors and 63,318 putative non-inhibitors correctly identified 93.53%~ 95.01% inhibitors and 99.81%~ 99.90% non-inhibitors in 5-fold cross validation studies. SVM trained by 1,703 inhibitors reported before 2011 and 63,318 putative non-inhibitors correctly identified 70.45% of the 44 inhibitors reported since 2011, and predicted as inhibitors 44,843 (0.33% of 13.56M PubChem, 1,496 (0.89% of 168 K MDDR, and 719 (7.73% of 9,305 MDDR compounds similar to the known inhibitors. Conclusions SVM showed comparable yield and reduced false hit rates in searching large compound libraries compared to the similarity-based and other machine-learning VS methods developed from the same set of training compounds and molecular descriptors. We tested three virtual hits of the same novel scaffold from in-house chemical libraries not reported as Src inhibitor, one of which showed moderate activity. SVM may be potentially explored for searching Src inhibitors from large compound libraries at low false-hit rates.
Development and experimental test of support vector machines virtual screening method for searching Src inhibitors from large compound libraries.

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Han, Bucong; Ma, Xiaohua; Zhao, Ruiying; Zhang, Jingxian; Wei, Xiaona; Liu, Xianghui; Liu, Xin; Zhang, Cunlong; Tan, Chunyan; Jiang, Yuyang; Chen, Yuzong

2012-11-23

Src plays various roles in tumour progression, invasion, metastasis, angiogenesis and survival. It is one of the multiple targets of multi-target kinase inhibitors in clinical uses and trials for the treatment of leukemia and other cancers. These successes and appearances of drug resistance in some patients have raised significant interest and efforts in discovering new Src inhibitors. Various in-silico methods have been used in some of these efforts. It is desirable to explore additional in-silico methods, particularly those capable of searching large compound libraries at high yields and reduced false-hit rates. We evaluated support vector machines (SVM) as virtual screening tools for searching Src inhibitors from large compound libraries. SVM trained and tested by 1,703 inhibitors and 63,318 putative non-inhibitors correctly identified 93.53%~ 95.01% inhibitors and 99.81%~ 99.90% non-inhibitors in 5-fold cross validation studies. SVM trained by 1,703 inhibitors reported before 2011 and 63,318 putative non-inhibitors correctly identified 70.45% of the 44 inhibitors reported since 2011, and predicted as inhibitors 44,843 (0.33%) of 13.56M PubChem, 1,496 (0.89%) of 168 K MDDR, and 719 (7.73%) of 9,305 MDDR compounds similar to the known inhibitors. SVM showed comparable yield and reduced false hit rates in searching large compound libraries compared to the similarity-based and other machine-learning VS methods developed from the same set of training compounds and molecular descriptors. We tested three virtual hits of the same novel scaffold from in-house chemical libraries not reported as Src inhibitor, one of which showed moderate activity. SVM may be potentially explored for searching Src inhibitors from large compound libraries at low false-hit rates.
Revitalizing the Library OPAC: Interface, Searching, and Display Challenges

Directory of Open Access Journals (Sweden)

Jia Mi

2008-03-01

Full Text Available The behavior of academic library users has drastically changed in recent years. Internet search engines have become the preferred tool over the library online public access catalog (OPAC for finding information. Libraries are losing ground to online search engines. In this paper, two aspects of OPAC use are studied: (1 the current OPAC interface and searching capabilities, and (2 the OPAC bibliographic display. The purpose of the study is to find answers to the following questions: Why is the current OPAC ineffective? What can libraries and librarians do to deliver an OPAC that is as good as search engines to better serve our users? Revitalizing the library OPAC is one of the pressing issues that has to be accomplished.
Federated Search and the Library Web Site: A Study of Association of Research Libraries Member Web Sites

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Williams, Sarah C.

2010-01-01

The purpose of this study was to investigate how federated search engines are incorporated into the Web sites of libraries in the Association of Research Libraries. In 2009, information was gathered for each library in the Association of Research Libraries with a federated search engine. This included the name of the federated search service and…
Flexible digital library search

NARCIS (Netherlands)

Windhouwer, M.; Schmidt, A.; Zwol, van R.; Petkovic, M.; Blok, H.E.; Dahanayake, A.; Gerhardt, W.

2003-01-01

In this chapter the development of a specialised search engine for a digital library is described. The proposed system architecture consists of three levels: the conceptual, the logical and the physical level. The conceptual level schema enables by its exposure of a domain specific schema
Using a Google Search Appliance (GSA) to search digital library collections: a case study of the INIS Collection Search

OpenAIRE

Savic, Dobrica

2014-01-01

Libraries are facing many challenges today. In addition to diminishing funding and increased user expectations, the use of classic library catalogues is becoming an additional challenge. Library users require fast and easy access to information resources regardless whether the format used is paper or electronic. Google search, with its speed and simplicity, set up a new standard for information retrieval which is hard to achieve with the previous generation of library search facilities. Put i...
Virtual screening methods as tools for drug lead discovery from large chemical libraries.

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Ma, X H; Zhu, F; Liu, X; Shi, Z; Zhang, J X; Yang, S Y; Wei, Y Q; Chen, Y Z

2012-01-01

Virtual screening methods have been developed and explored as useful tools for searching drug lead compounds from chemical libraries, including large libraries that have become publically available. In this review, we discussed the new developments in exploring virtual screening methods for enhanced performance in searching large chemical libraries, their applications in screening libraries of ~ 1 million or more compounds in the last five years, the difficulties in their applications, and the strategies for further improving these methods.
Manually Classifying User Search Queries on an Academic Library Web Site

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Chapman, Suzanne; Desai, Shevon; Hagedorn, Kat; Varnum, Ken; Mishra, Sonali; Piacentine, Julie

2013-01-01

The University of Michigan Library wanted to learn more about the kinds of searches its users were conducting through the "one search" search box on the Library Web site. Library staff conducted two investigations. A preliminary investigation in 2011 involved the manual review of the 100 most frequently occurring queries conducted…
Developing as new search engine and browser for libraries to search and organize the World Wide Web library resources

OpenAIRE

Sreenivasulu, V.

2000-01-01

Internet Granthalaya urges world wide advocates and targets at the task of creating a new search engine and dedicated browseer. Internet Granthalaya may be the ultimate search engine exclusively dedicated for every library use to search and organize the world wide web libary resources
Epsilon-Q: An Automated Analyzer Interface for Mass Spectral Library Search and Label-Free Protein Quantification.

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Cho, Jin-Young; Lee, Hyoung-Joo; Jeong, Seul-Ki; Paik, Young-Ki

2017-12-01

Mass spectrometry (MS) is a widely used proteome analysis tool for biomedical science. In an MS-based bottom-up proteomic approach to protein identification, sequence database (DB) searching has been routinely used because of its simplicity and convenience. However, searching a sequence DB with multiple variable modification options can increase processing time, false-positive errors in large and complicated MS data sets. Spectral library searching is an alternative solution, avoiding the limitations of sequence DB searching and allowing the detection of more peptides with high sensitivity. Unfortunately, this technique has less proteome coverage, resulting in limitations in the detection of novel and whole peptide sequences in biological samples. To solve these problems, we previously developed the "Combo-Spec Search" method, which uses manually multiple references and simulated spectral library searching to analyze whole proteomes in a biological sample. In this study, we have developed a new analytical interface tool called "Epsilon-Q" to enhance the functions of both the Combo-Spec Search method and label-free protein quantification. Epsilon-Q performs automatically multiple spectral library searching, class-specific false-discovery rate control, and result integration. It has a user-friendly graphical interface and demonstrates good performance in identifying and quantifying proteins by supporting standard MS data formats and spectrum-to-spectrum matching powered by SpectraST. Furthermore, when the Epsilon-Q interface is combined with the Combo-Spec search method, called the Epsilon-Q system, it shows a synergistic function by outperforming other sequence DB search engines for identifying and quantifying low-abundance proteins in biological samples. The Epsilon-Q system can be a versatile tool for comparative proteome analysis based on multiple spectral libraries and label-free quantification.
Fast parallel tandem mass spectral library searching using GPU hardware acceleration.

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Baumgardner, Lydia Ashleigh; Shanmugam, Avinash Kumar; Lam, Henry; Eng, Jimmy K; Martin, Daniel B

2011-06-03

Mass spectrometry-based proteomics is a maturing discipline of biologic research that is experiencing substantial growth. Instrumentation has steadily improved over time with the advent of faster and more sensitive instruments collecting ever larger data files. Consequently, the computational process of matching a peptide fragmentation pattern to its sequence, traditionally accomplished by sequence database searching and more recently also by spectral library searching, has become a bottleneck in many mass spectrometry experiments. In both of these methods, the main rate-limiting step is the comparison of an acquired spectrum with all potential matches from a spectral library or sequence database. This is a highly parallelizable process because the core computational element can be represented as a simple but arithmetically intense multiplication of two vectors. In this paper, we present a proof of concept project taking advantage of the massively parallel computing available on graphics processing units (GPUs) to distribute and accelerate the process of spectral assignment using spectral library searching. This program, which we have named FastPaSS (for Fast Parallelized Spectral Searching), is implemented in CUDA (Compute Unified Device Architecture) from NVIDIA, which allows direct access to the processors in an NVIDIA GPU. Our efforts demonstrate the feasibility of GPU computing for spectral assignment, through implementation of the validated spectral searching algorithm SpectraST in the CUDA environment.
Hunting for unexpected post-translational modifications by spectral library searching with tier-wise scoring.

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Ma, Chun Wai Manson; Lam, Henry

2014-05-02

Discovering novel post-translational modifications (PTMs) to proteins and detecting specific modification sites on proteins is one of the last frontiers of proteomics. At present, hunting for post-translational modifications remains challenging in widely practiced shotgun proteomics workflows due to the typically low abundance of modified peptides and the greatly inflated search space as more potential mass shifts are considered by the search engines. Moreover, most popular search methods require that the user specifies the modification(s) for which to search; therefore, unexpected and novel PTMs will not be detected. Here a new algorithm is proposed to apply spectral library searching to the problem of open modification searches, namely, hunting for PTMs without prior knowledge of what PTMs are in the sample. The proposed tier-wise scoring method intelligently looks for unexpected PTMs by allowing mass-shifted peak matches but only when the number of matches found is deemed statistically significant. This allows the search engine to search for unexpected modifications while maintaining its ability to identify unmodified peptides effectively at the same time. The utility of the method is demonstrated using three different data sets, in which the numbers of spectrum identifications to both unmodified and modified peptides were substantially increased relative to a regular spectral library search as well as to another open modification spectral search method, pMatch.
Searching for a New Way to Reach Patrons: A Search Engine Optimization Pilot Project at Binghamton University Libraries

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Rushton, Erin E.; Kelehan, Martha Daisy; Strong, Marcy A.

2008-01-01

Search engine use is one of the most popular online activities. According to a recent OCLC report, nearly all students start their electronic research using a search engine instead of the library Web site. Instead of viewing search engines as competition, however, librarians at Binghamton University Libraries decided to employ search engine…
Combination of Multiple Spectral Libraries Improves the Current Search Methods Used to Identify Missing Proteins in the Chromosome-Centric Human Proteome Project.

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Cho, Jin-Young; Lee, Hyoung-Joo; Jeong, Seul-Ki; Kim, Kwang-Youl; Kwon, Kyung-Hoon; Yoo, Jong Shin; Omenn, Gilbert S; Baker, Mark S; Hancock, William S; Paik, Young-Ki

2015-12-04

Approximately 2.9 billion long base-pair human reference genome sequences are known to encode some 20 000 representative proteins. However, 3000 proteins, that is, ~15% of all proteins, have no or very weak proteomic evidence and are still missing. Missing proteins may be present in rare samples in very low abundance or be only temporarily expressed, causing problems in their detection and protein profiling. In particular, some technical limitations cause missing proteins to remain unassigned. For example, current mass spectrometry techniques have high limits and error rates for the detection of complex biological samples. An insufficient proteome coverage in a reference sequence database and spectral library also raises major issues. Thus, the development of a better strategy that results in greater sensitivity and accuracy in the search for missing proteins is necessary. To this end, we used a new strategy, which combines a reference spectral library search and a simulated spectral library search, to identify missing proteins. We built the human iRefSPL, which contains the original human reference spectral library and additional peptide sequence-spectrum match entries from other species. We also constructed the human simSPL, which contains the simulated spectra of 173 907 human tryptic peptides determined by MassAnalyzer (version 2.3.1). To prove the enhanced analytical performance of the combination of the human iRefSPL and simSPL methods for the identification of missing proteins, we attempted to reanalyze the placental tissue data set (PXD000754). The data from each experiment were analyzed using PeptideProphet, and the results were combined using iProphet. For the quality control, we applied the class-specific false-discovery rate filtering method. All of the results were filtered at a false-discovery rate of libraries, iRefSPL and simSPL, were designed to ensure no overlap of the proteome coverage. They were shown to be complementary to spectral library
Evaluation of Federated Searching Options for the School Library

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Abercrombie, Sarah E.

2008-01-01

Three hosted federated search tools, Follett One Search, Gale PowerSearch Plus, and WebFeat Express, were configured and implemented in a school library. Databases from five vendors and the OPAC were systematically searched. Federated search results were compared with each other and to the results of the same searches in the database's native…

Discovering How Students Search a Library Web Site: A Usability Case Study.

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Augustine, Susan; Greene, Courtney

2002-01-01

Discusses results of a usability study at the University of Illinois Chicago that investigated whether Internet search engines have influenced the way students search library Web sites. Results show students use the Web site's internal search engine rather than navigating through the pages; have difficulty interpreting library terminology; and…
Using Google Search Appliance (GSA) to search digital library collections: A Case Study of the INIS Collection Search

International Nuclear Information System (INIS)

Savic, Dobrica

2014-01-01

Google Search has established a new standard for information retrieval which did not exist with previous generations of library search facilities. The INIS hosts one of the world’s largest collections of published information on the peaceful uses of nuclear science and technology. It offers on-line access to a unique collection of 3.6 million bibliographic records and 483,000 full texts of non-conventional (grey) literature. This large digital library collection suffered from most of the well-known shortcomings of the classic library catalogue. Searching was complex and complicated, it required training in Boolean logic, full-text searching was not an option, and response time was slow. An opportune moment to improve the system came with the retirement of the previous catalogue software and the adoption of GSA as an organization-wide search engine standard. INIS was quick to realize the potential of using such a well-known application to replace its on-line catalogue. This paper presents the advantages and disadvantages encountered during three years of GSA use. Based on specific INIS-based practice and experience, this paper also offers some guidelines on ways to improve classic collections of millions of bibliographic and full-text documents, while reaping multiple benefits, such as increased use, accessibility, usability, expandability and improving user search and retrieval experiences. (author)
Flexible and scalable digital library search

NARCIS (Netherlands)

M.A. Windhouwer (Menzo); A.R. Schmidt; R. van Zwol; M. Petkovic; H.E. Blok

2001-01-01

textabstractIn this report the development of a specialised search engine for a digital library is described. The proposed system architecture consists of three levels: the conceptual, the logical and the physical level. The conceptual level schema enables by its exposure of a domain specific
Library Catalogue Users Are Influenced by Trends in Web Searching Search Strategies. A review of: Novotny, Eric. “I Don’t Think I Click: A Protocol Analysis Study of Use of a Library Online Catalog in the Internet Age.” College & Research Libraries, 65.6 (Nov. 2004: 525-37.

Directory of Open Access Journals (Sweden)

Susan Haigh

2006-09-01

Full Text Available Objective – To explore how Web-savvy users think about and search an online catalogue. Design – Protocol analysis study. Setting – Academic library (Pennsylvania State University Libraries. Subjects – Eighteen users (17 students, 1 faculty member of an online public access catalog, divided into two groups of nine first-time and nine experienced users. Method – The study team developed five tasks that represented a range of activities commonly performed by library users, such as searching for a specific item, identifying a library location, and requesting a copy. Seventeen students and one faculty member, divided evenly between novice and experienced searchers, were recruited to “think aloud” through the performance of the tasks. Data were gathered through audio recordings, screen capture software, and investigator notes. The time taken for each task was recorded, and investigators rated task completion as “successful,” “partially successful,” “fail,” or “search aborted.” After the searching session, participants were interviewed to clarify their actions and provide further commentary on the catalogue search. Main results – Participants in both test groups were relatively unsophisticated subject searchers. They made minimal use of Boolean operators, and tended not to repair failed searches by rethinking the search vocabulary and using synonyms. Participants did not have a strong understanding of library catalogue contents or structure and showed little curiosity in developing an understanding of how to utilize the catalogue. Novice users were impatient both in choosing search options and in evaluating their search results. They assumed search results were sorted by relevance, and thus would not typically browse past the initial screen. They quickly followed links, fearlessly tried different searches and options, and rapidly abandoned false trails. Experienced users were more effective and efficient searchers than
Investigating User Search Tactic Patterns and System Support in Using Digital Libraries

Science.gov (United States)

Joo, Soohyung

2013-01-01

This study aims to investigate users' search tactic application and system support in using digital libraries. A user study was conducted with sixty digital library users. The study was designed to answer three research questions: 1) How do users engage in a search process by applying different types of search tactics while conducting different…
MetaSearching and Beyond: Implementation Experiences and Advice from an Academic Library

Directory of Open Access Journals (Sweden)

Gail Herrera

2007-06-01

Full Text Available In March 2003 the University of Mississippi Libraries made our MetaSearch tool publicly available. After a year of working with this product and integrating it into the library Web site, a wide variety of libraries interested in our implementation process and experiences began to call. Libraries interested in this product have included consortia, public, and academic libraries in the United States, Mexico, and Europe. This article was written in an effort to share the recommendations and concerns given. Much of the advice is general and could be applied to many of the MetaSearch tools available. Google Scholar and other open Web initiatives that could impact the future of MetaSearching are also discussed.
Usability Testing of a Large, Multidisciplinary Library Database: Basic Search and Visual Search

Directory of Open Access Journals (Sweden)

Jody Condit Fagan

2006-09-01

Full Text Available Visual search interfaces have been shown by researchers to assist users with information search and retrieval. Recently, several major library vendors have added visual search interfaces or functions to their products. For public service librarians, perhaps the most critical area of interest is the extent to which visual search interfaces and text-based search interfaces support research. This study presents the results of eight full-scale usability tests of both the EBSCOhost Basic Search and Visual Search in the context of a large liberal arts university.
Improving e-book access via a library-developed full-text search tool.

Science.gov (United States)

Foust, Jill E; Bergen, Phillip; Maxeiner, Gretchen L; Pawlowski, Peter N

2007-01-01

This paper reports on the development of a tool for searching the contents of licensed full-text electronic book (e-book) collections. The Health Sciences Library System (HSLS) provides services to the University of Pittsburgh's medical programs and large academic health system. The HSLS has developed an innovative tool for federated searching of its e-book collections. Built using the XML-based Vivísimo development environment, the tool enables a user to perform a full-text search of over 2,500 titles from the library's seven most highly used e-book collections. From a single "Google-style" query, results are returned as an integrated set of links pointing directly to relevant sections of the full text. Results are also grouped into categories that enable more precise retrieval without reformulation of the search. A heuristic evaluation demonstrated the usability of the tool and a web server log analysis indicated an acceptable level of usage. Based on its success, there are plans to increase the number of online book collections searched. This library's first foray into federated searching has produced an effective tool for searching across large collections of full-text e-books and has provided a good foundation for the development of other library-based federated searching products.
Virtual Reference Services through Web Search Engines: Study of Academic Libraries in Pakistan

Directory of Open Access Journals (Sweden)

Rubia Khan

2017-03-01

Full Text Available Web search engines (WSE are powerful and popular tools in the field of information service management. This study is an attempt to examine the impact and usefulness of web search engines in providing virtual reference services (VRS within academic libraries in Pakistan. The study also attempts to investigate the relevant expertise and skills of library professionals in providing digital reference services (DRS efficiently using web search engines. Methodology used in this study is quantitative in nature. The data was collected from fifty public and private sector universities in Pakistan using a structured questionnaire. Microsoft Excel and SPSS were used for data analysis. The study concludes that web search engines are commonly used by librarians to help users (especially research scholars by providing digital reference services. The study also finds a positive correlation between use of web search engines and quality of digital reference services provided to library users. It is concluded that although search engines have increased the expectations of users and are really big competitors to a library’s reference desk, they are however not an alternative to reference service. Findings reveal that search engines pose numerous challenges for librarians and the study also attempts to bring together possible remedial measures. This study is useful for library professionals to understand the importance of search engines in providing VRS. The study also provides an intellectual comparison among different search engines, their capabilities, limitations, challenges and opportunities to provide VRS effectively in libraries.
Improving e-book access via a library-developed full-text search tool*

Science.gov (United States)

Foust, Jill E.; Bergen, Phillip; Maxeiner, Gretchen L.; Pawlowski, Peter N.

2007-01-01

Purpose: This paper reports on the development of a tool for searching the contents of licensed full-text electronic book (e-book) collections. Setting: The Health Sciences Library System (HSLS) provides services to the University of Pittsburgh's medical programs and large academic health system. Brief Description: The HSLS has developed an innovative tool for federated searching of its e-book collections. Built using the XML-based Vivísimo development environment, the tool enables a user to perform a full-text search of over 2,500 titles from the library's seven most highly used e-book collections. From a single “Google-style” query, results are returned as an integrated set of links pointing directly to relevant sections of the full text. Results are also grouped into categories that enable more precise retrieval without reformulation of the search. Results/Evaluation: A heuristic evaluation demonstrated the usability of the tool and a web server log analysis indicated an acceptable level of usage. Based on its success, there are plans to increase the number of online book collections searched. Conclusion: This library's first foray into federated searching has produced an effective tool for searching across large collections of full-text e-books and has provided a good foundation for the development of other library-based federated searching products. PMID:17252065
Novel search algorithms for a mid-infrared spectral library of cotton contaminants.

Science.gov (United States)

Loudermilk, J Brian; Himmelsbach, David S; Barton, Franklin E; de Haseth, James A

2008-06-01

During harvest, a variety of plant based contaminants are collected along with cotton lint. The USDA previously created a mid-infrared, attenuated total reflection (ATR), Fourier transform infrared (FT-IR) spectral library of cotton contaminants for contaminant identification as the contaminants have negative impacts on yarn quality. This library has shown impressive identification rates for extremely similar cellulose based contaminants in cases where the library was representative of the samples searched. When spectra of contaminant samples from crops grown in different geographic locations, seasons, and conditions and measured with a different spectrometer and accessories were searched, identification rates for standard search algorithms decreased significantly. Six standard algorithms were examined: dot product, correlation, sum of absolute values of differences, sum of the square root of the absolute values of differences, sum of absolute values of differences of derivatives, and sum of squared differences of derivatives. Four categories of contaminants derived from cotton plants were considered: leaf, stem, seed coat, and hull. Experiments revealed that the performance of the standard search algorithms depended upon the category of sample being searched and that different algorithms provided complementary information about sample identity. These results indicated that choosing a single standard algorithm to search the library was not possible. Three voting scheme algorithms based on result frequency, result rank, category frequency, or a combination of these factors for the results returned by the standard algorithms were developed and tested for their capability to overcome the unpredictability of the standard algorithms' performances. The group voting scheme search was based on the number of spectra from each category of samples represented in the library returned in the top ten results of the standard algorithms. This group algorithm was able to identify
Systematic reviews in Library and Information Science: analysis and evaluation of the search process

Directory of Open Access Journals (Sweden)

José Antonio Salvador-Oliván

2018-05-01

Full Text Available Objective: An essential component of a systematic review is the development and execution of a literature search to identify all available and relevant published studies. The main objective of this study is to analyse and evaluate whether the systematic reviews in Library and Information Science (LIS provide complete information on all the elements that make up the search process. Methods: A search was launched in WOS, Scopus, LISTA, Library Science Database, Medline databases and a wiki published from 2000 to February 2017, in order to find and identify systematic reviews. The search was designed to find those records whose titles included the words “systematic review” and/or “meta-analysis”. A list was created with the twelve items recommended from of the main publication guides, to assess the information degree on each of them. Results and conclusions: Most of the reviews in LIS are created by information professionals. From the 94 systematic reviews selected for analysis, it was found that only a 4.3% provided the complete reporting on the search method. The most frequently included item is the name of the database (95.6% and the least one is the name of the host (35.8%. It is necessary to improve and complete the information about the search processes in the complete reports from LIS systematic reviews for reproducibility, updating and quality assessment improvement.
The Impact of On-line Searching on Document Supply Services at Individual Libraries

Science.gov (United States)

Hosono, Kimio; Tanaka, Isao; Fukazawa, Yoshiko

As use of on-line searching services has progressed in libraries, requests on primary materials have increased much more than before. For the purpose of clarifying this trend and countermeasures against it a survey by questionnaire was conducted in 1985. The respondants from totally 112 libraries are as follows ; 60 industrial libraries, 41 academic libraries and 11 libraries of research institutes and laboratories. It was shown that industrial libraries have received more requests on primary materials mostly resulting from on-line searching while the requests have not increased remarkably in academic libraries. Regardless the type of libraries, almost all libraries can not fully meet the requests with their own collection so that industrial libraries have to rely on external information services and academic libraries utilize interlibrary loan system. Requests are sent via on-line from industrial libraries, and by mail from academic libraries. In fact, any-libraries are not likely to review their material-collecting policy. Therefore it is urgent to establish the system which enables use of external information services or interlibrary loan system more than ever.
Encounters with the OPAC: On-Line Searching in Public Libraries.

Science.gov (United States)

Slone, Deborah J.

2000-01-01

Reports on a qualitative study that explored strategies and behaviors of public library users during interaction with an online public access catalog, and users' confidence in finding needed information online. Discusses results of questionnaires, interviews, and observations that examined unknown-item searches, area searches, and known-item…
Making the Most of Libraries in the Search for Academic Excellence.

Science.gov (United States)

Breivik, Patricia Senn

1987-01-01

The role of libraries in the search for quality education was addressed in the Carnegie Foundation's report, "College," and at the first higher education conference on academic libraries. Information literacy and policy, campus organizational issues, and programs in economic development support, active learning, and faculty development…
Using a Google Search Appliance (GSA to search digital library collections: a case study of the INIS Collection Search

Directory of Open Access Journals (Sweden)

Dobrica Savic

2014-05-01

The International Nuclear Information System (INIS hosts one of the world’s largest collections of published information on the peaceful uses of nuclear science and technology. It offers online access to a unique collection of 3.6 million bibliographic records and 320,000 full-texts of non-conventional (grey literature. This large digital library collection suffered from most of the well-known shortcomings of the classic library catalogue. Searching was complex and complicated, required some training in using Boolean logic, full-text searching was not an option, and the response time was slow. An opportune moment came with the retirement of the previous catalogue software and with the adoption of Google Search Appliance (GSA as an organization-wide search engine standard. INIS was quick to realize a great potential in using such a well-known application as a replacement for its online catalogue and this paper presents the advantages and disadvantages encountered during three years of GSA use. Based on specific INIS-based practice and experience, this paper also offers some guidelines on ways to improve classic collections of millions of bibliographic and full-text documents, while achieving multiple benefits such as increased use, accessibility, usability, expandability and improving the user search and retrieval experience.
Paths of discovery: Comparing the search effectiveness of EBSCO Discovery Service, Summon, Google Scholar, and conventional library resources.

Directory of Open Access Journals (Sweden)

Müge Akbulut

2015-09-01

Full Text Available It is becoming hard for users to select significant sources among many others as number of scientific publications increase (Henning and Gunn, 2012. Search engines that are using cloud computing methods such as Google can list related documents successfully answering user requirements (Johnson, Levine and Smith, 2009. In order to meet users’ increasing demands, libraries started to use systems which enable users to access printed and electronic sources through a single interface. This study uses quantitative and qualitative methods to compare search effectiveness between Serial Solutions Summon, EBSCO Discovery Service (EDS web discovery tools, Google Scholar (GS and conventional library databases among users from Bucknell University and Illinois Wesleyan University.
Library search with regular reflectance IR spectra

International Nuclear Information System (INIS)

Staat, H.; Korte, E.H.; Lampen, P.

1989-01-01

Characterisation in situ for coatings and other surface layers is generally favourable, but a prerequisite for precious items such as art objects. In infrared spectroscopy only reflection techniques are applicable here. However for attenuated total reflection (ATR) it is difficult to obtain the necessary optical contact of the crystal with the sample, when the latter is not perfectly plane or flexible. The measurement of diffuse reflectance demands a scattering sample and usually the reflectance is very poor. Therefore in most cases one is left with regular reflectance. Such spectra consist of dispersion-like feature instead of bands impeding their interpretation in the way the analyst is used to. Furthermore for computer search in common spectral libraries compiled from transmittance or absorbance spectra a transformation of the reflectance spectra is needed. The correct conversion is based on the Kramers-Kronig transformation. This somewhat time - consuming procedure can be speeded up by using appropriate approximations. A coarser conversion may be obtained from the first derivative of the reflectance spectrum which resembles the second derivative of a transmittance spectrum. The resulting distorted spectra can still be used successfully for the search in peak table libraries. Experiences with both transformations are presented. (author)
Optimization of axial enrichment distribution for BWR fuels using scoping libraries and block coordinate descent method

Energy Technology Data Exchange (ETDEWEB)

Tung, Wu-Hsiung, E-mail: wstong@iner.gov.tw; Lee, Tien-Tso; Kuo, Weng-Sheng; Yaur, Shung-Jung

2017-03-15

Highlights: • An optimization method for axial enrichment distribution in a BWR fuel was developed. • Block coordinate descent method is employed to search for optimal solution. • Scoping libraries are used to reduce computational effort. • Optimization search space consists of enrichment difference parameters. • Capability of the method to find optimal solution is demonstrated. - Abstract: An optimization method has been developed to search for the optimal axial enrichment distribution in a fuel assembly for a boiling water reactor core. The optimization method features: (1) employing the block coordinate descent method to find the optimal solution in the space of enrichment difference parameters, (2) using scoping libraries to reduce the amount of CASMO-4 calculation, and (3) integrating a core critical constraint into the objective function that is used to quantify the quality of an axial enrichment design. The objective function consists of the weighted sum of core parameters such as shutdown margin and critical power ratio. The core parameters are evaluated by using SIMULATE-3, and the cross section data required for the SIMULATE-3 calculation are generated by using CASMO-4 and scoping libraries. The application of the method to a 4-segment fuel design (with the highest allowable segment enrichment relaxed to 5%) demonstrated that the method can obtain an axial enrichment design with improved thermal limit ratios and objective function value while satisfying the core design constraints and core critical requirement through the use of an objective function. The use of scoping libraries effectively reduced the number of CASMO-4 calculation, from 85 to 24, in the 4-segment optimization case. An exhausted search was performed to examine the capability of the method in finding the optimal solution for a 4-segment fuel design. The results show that the method found a solution very close to the optimum obtained by the exhausted search. The number of
Digging in the Mines: Mining Course Syllabi in Search of the Library

Directory of Open Access Journals (Sweden)

Keven M. Jeffery

2017-03-01

Full Text Available Objective - The purpose of this study was to analyze a syllabus collection at a large, public university to identify how the university’s library was represented within the syllabi. Specifically, this study was conducted to see which library spaces, resources, and people were included in course syllabi and to identify possible opportunities for library engagement. Methods - A text analysis software called QDA Miner was used to search using keywords and analyze 1,226 syllabi across eight colleges at both the undergraduate and graduate levels from the Fall 2014 semester. Results - Of the 1,226 syllabi analyzed, 665 did not mention the library’s services, spaces, or resources nor did they mention projects requiring research. Of the remaining 561, the text analysis revealed that the highest relevant keyword matches were related to Citation Management (286, Resource Intensive Projects (262, and Library Spaces (251. Relationships between categories were mapped using Sorensen’s coefficient of similarity. Library Space and Library Resources (coefficient =.500 and Library Space and Library Services (coefficient-=.457 were most likely to appear in the same syllabi, with Citation Management and Resource Intensive Projects (coefficient=.445 the next most likely to co-occur. Conclusion - The text analysis proved to be effective at identifying how and where the library was mentioned in course syllabi. This study revealed instructional and research engagement opportunities for the library’s liaisons, and it revealed the ways in which the library’s space was presented to students. Additionally, the faculty’s research expectations for students in their disciplines were better understood.

The Role of Libraries in the Search for Educational Excellence.

Science.gov (United States)

Breivik, Patricia Senn

1987-01-01

Discusses ways in which libraries can make a major contribution to the search for educational excellence and urges librarians to make a concerted effort to capture the attention of educational leaders. Four references are listed. (MES)
Performance of Ruecking's Word-compression Method When Applied to Machine Retrieval from a Library Catalog

Directory of Open Access Journals (Sweden)

Ben-Ami Lipetz

1969-12-01

Full Text Available F. H. Ruecking's word-compression algorithm for retrieval of bibliographic data from computer stores was tested for performance in matching user-supplied, unedited bibliographic data to the bibliographic data contained in a library catalog. The algorithm was tested by manual simulation, using data derived from 126 case studies of successful manual searches of the card catalog at Sterling Memorial Library, Yale University. The algorithm achieved 70% recall in comparison to conventional searching. Its accepta- bility as a substitute for conventional catalog searching methods is ques- tioned unless recall performance can be improved, either by use of the algorithm alone or in combination with other algorithms.
A Search method for Scientific Data in Digital Libraries, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — Unlike the world wide web or general libraries, digital libraries typically serve a specialized community of experts sharing a relatively narrow focus, such as some...
Using internet search engines and library catalogs to locate toxicology information.

Science.gov (United States)

Wukovitz, L D

2001-01-12

The increasing importance of the Internet demands that toxicologists become aquainted with its resources. To find information, researchers must be able to effectively use Internet search engines, directories, subject-oriented websites, and library catalogs. The article will explain these resources, explore their benefits and weaknesses, and identify skills that help the researcher to improve search results and critically evaluate sources for their relevancy, validity, accuracy, and timeliness.
Combining Fragment-Ion and Neutral-Loss Matching during Mass Spectral Library Searching: A New General Purpose Algorithm Applicable to Illicit Drug Identification.

Science.gov (United States)

Moorthy, Arun S; Wallace, William E; Kearsley, Anthony J; Tchekhovskoi, Dmitrii V; Stein, Stephen E

2017-12-19

A mass spectral library search algorithm that identifies compounds that differ from library compounds by a single "inert" structural component is described. This algorithm, the Hybrid Similarity Search, generates a similarity score based on matching both fragment ions and neutral losses. It employs the parameter DeltaMass, defined as the mass difference between query and library compounds, to shift neutral loss peaks in the library spectrum to match corresponding neutral loss peaks in the query spectrum. When the spectra being compared differ by a single structural feature, these matching neutral loss peaks should contain that structural feature. This method extends the scope of the library to include spectra of "nearest-neighbor" compounds that differ from library compounds by a single chemical moiety. Additionally, determination of the structural origin of the shifted peaks can aid in the determination of the chemical structure and fragmentation mechanism of the query compound. A variety of examples are presented, including the identification of designer drugs and chemical derivatives not present in the library.
Google vs. the Library (Part II): Student Search Patterns and Behaviors When Using Google and a Federated Search Tool

Science.gov (United States)

Georgas, Helen

2014-01-01

This study examines the information-seeking behavior of undergraduate students within a research context. Student searches were recorded while the participants used Google and a library (federated) search tool to find sources (one book, two articles, and one other source of their choosing) for a selected topic. The undergraduates in this study…
Library fingerprints: a novel approach to the screening of virtual libraries.

Science.gov (United States)

Klon, Anthony E; Diller, David J

2007-01-01

We propose a novel method to prioritize libraries for combinatorial synthesis and high-throughput screening that assesses the viability of a particular library on the basis of the aggregate physical-chemical properties of the compounds using a naïve Bayesian classifier. This approach prioritizes collections of related compounds according to the aggregate values of their physical-chemical parameters in contrast to single-compound screening. The method is also shown to be useful in screening existing noncombinatorial libraries when the compounds in these libraries have been previously clustered according to their molecular graphs. We show that the method used here is comparable or superior to the single-compound virtual screening of combinatorial libraries and noncombinatorial libraries and is superior to the pairwise Tanimoto similarity searching of a collection of combinatorial libraries.
Paths of Discovery: Comparing the Search Effectiveness of EBSCO Discovery Service, Summon, Google Scholar, and Conventional Library Resources

Science.gov (United States)

Asher, Andrew D.; Duke, Lynda M.; Wilson, Suzanne

2013-01-01

In 2011, researchers at Bucknell University and Illinois Wesleyan University compared the search efficacy of Serial Solutions Summon, EBSCO Discovery Service, Google Scholar, and conventional library databases. Using a mixed-methods approach, qualitative and quantitative data were gathered on students' usage of these tools. Regardless of the…
A protein-dependent side-chain rotamer library.

KAUST Repository

Bhuyan, M.S.; Gao, Xin

2011-01-01

Protein side-chain packing problem has remained one of the key open problems in bioinformatics. The three main components of protein side-chain prediction methods are a rotamer library, an energy function and a search algorithm. Rotamer libraries summarize the existing knowledge of the experimentally determined structures quantitatively. Depending on how much contextual information is encoded, there are backbone-independent rotamer libraries and backbone-dependent rotamer libraries. Backbone-independent libraries only encode sequential information, whereas backbone-dependent libraries encode both sequential and locally structural information. However, side-chain conformations are determined by spatially local information, rather than sequentially local information. Since in the side-chain prediction problem, the backbone structure is given, spatially local information should ideally be encoded into the rotamer libraries. In this paper, we propose a new type of backbone-dependent rotamer library, which encodes structural information of all the spatially neighboring residues. We call it protein-dependent rotamer libraries. Given any rotamer library and a protein backbone structure, we first model the protein structure as a Markov random field. Then the marginal distributions are estimated by the inference algorithms, without doing global optimization or search. The rotamers from the given library are then re-ranked and associated with the updated probabilities. Experimental results demonstrate that the proposed protein-dependent libraries significantly outperform the widely used backbone-dependent libraries in terms of the side-chain prediction accuracy and the rotamer ranking ability. Furthermore, without global optimization/search, the side-chain prediction power of the protein-dependent library is still comparable to the global-search-based side-chain prediction methods.
A protein-dependent side-chain rotamer library.

KAUST Repository

Bhuyan, M.S.

2011-12-14

Protein side-chain packing problem has remained one of the key open problems in bioinformatics. The three main components of protein side-chain prediction methods are a rotamer library, an energy function and a search algorithm. Rotamer libraries summarize the existing knowledge of the experimentally determined structures quantitatively. Depending on how much contextual information is encoded, there are backbone-independent rotamer libraries and backbone-dependent rotamer libraries. Backbone-independent libraries only encode sequential information, whereas backbone-dependent libraries encode both sequential and locally structural information. However, side-chain conformations are determined by spatially local information, rather than sequentially local information. Since in the side-chain prediction problem, the backbone structure is given, spatially local information should ideally be encoded into the rotamer libraries. In this paper, we propose a new type of backbone-dependent rotamer library, which encodes structural information of all the spatially neighboring residues. We call it protein-dependent rotamer libraries. Given any rotamer library and a protein backbone structure, we first model the protein structure as a Markov random field. Then the marginal distributions are estimated by the inference algorithms, without doing global optimization or search. The rotamers from the given library are then re-ranked and associated with the updated probabilities. Experimental results demonstrate that the proposed protein-dependent libraries significantly outperform the widely used backbone-dependent libraries in terms of the side-chain prediction accuracy and the rotamer ranking ability. Furthermore, without global optimization/search, the side-chain prediction power of the protein-dependent library is still comparable to the global-search-based side-chain prediction methods.
Library and information services: impact on patient care quality.

Science.gov (United States)

Marshall, Joanne Gard; Morgan, Jennifer Craft; Thompson, Cheryl A; Wells, Amber L

2014-01-01

The purpose of this paper is to explore library and information service impact on patient care quality. A large-scale critical incident survey of physicians and residents at 56 library sites serving 118 hospitals in the USA and Canada. Respondents were asked to base their answers on a recent incident in which they had used library resources to search for information related to a specific clinical case. Of 4,520 respondents, 75 percent said that they definitely or probably handled patient care differently using information obtained through the library. In a multivariate analysis, three summary clinical outcome measures were used as value and impact indicators: first, time saved; second, patient care changes; and third, adverse events avoided. The outcomes were examined in relation to four information access methods: first, asking librarian for assistance; second, performing search in a physical library; third, searching library's web site; or fourth, searching library resources on an institutional intranet. All library access methods had consistently positive relationships with the clinical outcomes, providing evidence that library services have a positive impact on patient care quality. Electronic collections and services provided by the library and the librarian contribute to patient care quality.
Data Analysis Methods for Library Marketing

Science.gov (United States)

Minami, Toshiro; Kim, Eunja

Our society is rapidly changing to information society, where the needs and requests of the people on information access are different widely from person to person. Library's mission is to provide its users, or patrons, with the most appropriate information. Libraries have to know the profiles of their patrons, in order to achieve such a role. The aim of library marketing is to develop methods based on the library data, such as circulation records, book catalogs, book-usage data, and others. In this paper we discuss the methodology and imporatnce of library marketing at the beginning. Then we demonstrate its usefulness through some examples of analysis methods applied to the circulation records in Kyushu University and Guacheon Library, and some implication that obtained as the results of these methods. Our research is a big beginning towards the future when library marketing is an unavoidable tool.
Optimization of search algorithms for a mass spectra library

International Nuclear Information System (INIS)

Domokos, L.; Henneberg, D.; Weimann, B.

1983-01-01

The SISCOM mass spectra library search is mainly an interpretative system producing a ''hit list'' of similar spectra based on six comparison factors. This paper deals with extension of the system; the aim is exact identification (retrieval) of those reference spectra in the SISCOM hit list that correspond to the unknown compounds or components of the mixture. Thus, instead of a similarity measure, a decision (retrieval) function is needed to establish the identity of reference and unknown compounds by comparison of their spectra. To facilitate estimation of the weightings of the different variables in the retrieval function, pattern recognition algorithms were applied. Numerous statistical evaluations of three different library collections were made to check the quality of data bases and to derive appropriate variables for the retrieval function. (Auth.)
Development of user-centered interfaces to search the knowledge resources of the Virginia Henderson International Nursing Library.

Science.gov (United States)

Jones, Josette; Harris, Marcelline; Bagley-Thompson, Cheryl; Root, Jane

2003-01-01

This poster describes the development of user-centered interfaces in order to extend the functionality of the Virginia Henderson International Nursing Library (VHINL) from library to web based portal to nursing knowledge resources. The existing knowledge structure and computational models are revised and made complementary. Nurses' search behavior is captured and analyzed, and the resulting search models are mapped to the revised knowledge structure and computational model.
[Progress in the spectral library based protein identification strategy].

Science.gov (United States)

Yu, Derui; Ma, Jie; Xie, Zengyan; Bai, Mingze; Zhu, Yunping; Shu, Kunxian

2018-04-25

Exponential growth of the mass spectrometry (MS) data is exhibited when the mass spectrometry-based proteomics has been developing rapidly. It is a great challenge to develop some quick, accurate and repeatable methods to identify peptides and proteins. Nowadays, the spectral library searching has become a mature strategy for tandem mass spectra based proteins identification in proteomics, which searches the experiment spectra against a collection of confidently identified MS/MS spectra that have been observed previously, and fully utilizes the abundance in the spectrum, peaks from non-canonical fragment ions, and other features. This review provides an overview of the implement of spectral library search strategy, and two key steps, spectral library construction and spectral library searching comprehensively, and discusses the progress and challenge of the library search strategy.
Ethnographic Methods in Academic Libraries: A Review

Science.gov (United States)

Ramsden, Bryony

2016-01-01

Research in academic libraries has recently seen an increase in the use of ethnographic-based methods to collect data. Primarily used to learn about library users and their interaction with spaces and resources, the methods are proving particularly useful to academic libraries. The data ethnographic methods retrieve is rich, context specific, and…
Evidential significance of automotive paint trace evidence using a pattern recognition based infrared library search engine for the Paint Data Query Forensic Database.

Science.gov (United States)

Lavine, Barry K; White, Collin G; Allen, Matthew D; Fasasi, Ayuba; Weakley, Andrew

2016-10-01

A prototype library search engine has been further developed to search the infrared spectral libraries of the paint data query database to identify the line and model of a vehicle from the clear coat, surfacer-primer, and e-coat layers of an intact paint chip. For this study, search prefilters were developed from 1181 automotive paint systems spanning 3 manufacturers: General Motors, Chrysler, and Ford. The best match between each unknown and the spectra in the hit list generated by the search prefilters was identified using a cross-correlation library search algorithm that performed both a forward and backward search. In the forward search, spectra were divided into intervals and further subdivided into windows (which corresponds to the time lag for the comparison) within those intervals. The top five hits identified in each search window were compiled; a histogram was computed that summarized the frequency of occurrence for each library sample, with the IR spectra most similar to the unknown flagged. The backward search computed the frequency and occurrence of each line and model without regard to the identity of the individual spectra. Only those lines and models with a frequency of occurrence greater than or equal to 20% were included in the final hit list. If there was agreement between the forward and backward search results, the specific line and model common to both hit lists was always the correct assignment. Samples assigned to the same line and model by both searches are always well represented in the library and correlate well on an individual basis to specific library samples. For these samples, one can have confidence in the accuracy of the match. This was not the case for the results obtained using commercial library search algorithms, as the hit quality index scores for the top twenty hits were always greater than 99%. Copyright © 2016 Elsevier B.V. All rights reserved.
Semantically Enriching the Search System of a Music Digital Library

Science.gov (United States)

de Juan, Paloma; Iglesias, Carlos

Traditional search systems are usually based on keywords, a very simple and convenient mechanism to express a need for information. This is the most popular way of searching the Web, although it is not always an easy task to accurately summarize a natural language query in a few keywords. Working with keywords means losing the context, which is the only thing that can help us deal with ambiguity. This is the biggest problem of keyword-based systems. Semantic Web technologies seem a perfect solution to this problem, since they make it possible to represent the semantics of a given domain. In this chapter, we present three projects, Harmos, Semusici and Cantiga, whose aim is to provide access to a music digital library. We will describe two search systems, a traditional one and a semantic one, developed in the context of these projects and compare them in terms of usability and effectiveness.
Library Search Prefilters for Vehicle Manufacturers to Assist in the Forensic Examination of Automotive Paints.

Science.gov (United States)

Lavine, Barry K; White, Collin G; Ding, Tao

2018-03-01

Pattern recognition techniques have been applied to the infrared (IR) spectral libraries of the Paint Data Query (PDQ) database to differentiate between nonidentical but similar IR spectra of automotive paints. To tackle the problem of library searching, search prefilters were developed to identify the vehicle make from IR spectra of the clear coat, surfacer-primer, and e-coat layers. To develop these search prefilters with the appropriate degree of accuracy, IR spectra from the PDQ database were preprocessed using the discrete wavelet transform to enhance subtle but significant features in the IR spectral data. Wavelet coefficients characteristic of vehicle make were identified using a genetic algorithm for pattern recognition and feature selection. Search prefilters to identify automotive manufacturer through IR spectra obtained from a paint chip recovered at a crime scene were developed using 1596 original manufacturer's paint systems spanning six makes (General Motors, Chrysler, Ford, Honda, Nissan, and Toyota) within a limited production year range (2000-2006). Search prefilters for vehicle manufacturer that were developed as part of this study were successfully validated using IR spectra obtained directly from the PDQ database. Information obtained from these search prefilters can serve to quantify the discrimination power of original automotive paint encountered in casework and further efforts to succinctly communicate trace evidential significance to the courts.
An Analysis of the Impact of Federated Search Products on Library Instruction Using the ACRL Standards

Science.gov (United States)

Cox, Christopher

2006-01-01

Federated search products are becoming more and more prevalent in academic libraries. What are the implications of this phenomenon for instruction librarians? An analysis of federated search products using the "Information Literacy Competency Standards for Higher Education" and a thorough review of the literature offer insight concerning whether…

Analysis of Users' Searches of CD-ROM Databases in the National and University Library in Zagreb.

Science.gov (United States)

Jokic, Maja

1997-01-01

Investigates the search behavior of CD-ROM database users in Zagreb (Croatia) libraries: one group needed a minimum of technical assistance, and the other was completely independent. Highlights include the use of questionnaires and transaction log analysis and the need for end-user education. The questionnaire and definitions of search process…
Information Retrieval Strategies of Millennial Undergraduate Students in Web and Library Database Searches

Science.gov (United States)

Porter, Brandi

2009-01-01

Millennial students make up a large portion of undergraduate students attending colleges and universities, and they have a variety of online resources available to them to complete academically related information searches, primarily Web based and library-based online information retrieval systems. The content, ease of use, and required search…
Google vs. the Library: Student Preferences and Perceptions when Doing Research Using Google and a Federated Search Tool

Science.gov (United States)

Georgas, Helen

2013-01-01

Federated searching was once touted as the library world's answer to Google, but ten years since federated searching technology's inception, how does it actually compare? This study focuses on undergraduate student preferences and perceptions when doing research using both Google and a federated search tool. Students were asked about their…
Development and tuning of an original search engine for patent libraries in medicinal chemistry.

Science.gov (United States)

Pasche, Emilie; Gobeill, Julien; Kreim, Olivier; Oezdemir-Zaech, Fatma; Vachon, Therese; Lovis, Christian; Ruch, Patrick

2014-01-01

The large increase in the size of patent collections has led to the need of efficient search strategies. But the development of advanced text-mining applications dedicated to patents of the biomedical field remains rare, in particular to address the needs of the pharmaceutical & biotech industry, which intensively uses patent libraries for competitive intelligence and drug development. We describe here the development of an advanced retrieval engine to search information in patent collections in the field of medicinal chemistry. We investigate and combine different strategies and evaluate their respective impact on the performance of the search engine applied to various search tasks, which covers the putatively most frequent search behaviours of intellectual property officers in medical chemistry: 1) a prior art search task; 2) a technical survey task; and 3) a variant of the technical survey task, sometimes called known-item search task, where a single patent is targeted. The optimal tuning of our engine resulted in a top-precision of 6.76% for the prior art search task, 23.28% for the technical survey task and 46.02% for the variant of the technical survey task. We observed that co-citation boosting was an appropriate strategy to improve prior art search tasks, while IPC classification of queries was improving retrieval effectiveness for technical survey tasks. Surprisingly, the use of the full body of the patent was always detrimental for search effectiveness. It was also observed that normalizing biomedical entities using curated dictionaries had simply no impact on the search tasks we evaluate. The search engine was finally implemented as a web-application within Novartis Pharma. The application is briefly described in the report. We have presented the development of a search engine dedicated to patent search, based on state of the art methods applied to patent corpora. We have shown that a proper tuning of the system to adapt to the various search tasks
Detection and identification of 700 drugs by multi-target screening with a 3200 Q TRAP LC-MS/MS system and library searching.

Science.gov (United States)

Dresen, S; Ferreirós, N; Gnann, H; Zimmermann, R; Weinmann, W

2010-04-01

The multi-target screening method described in this work allows the simultaneous detection and identification of 700 drugs and metabolites in biological fluids using a hybrid triple-quadrupole linear ion trap mass spectrometer in a single analytical run. After standardization of the method, the retention times of 700 compounds were determined and transitions for each compound were selected by a "scheduled" survey MRM scan, followed by an information-dependent acquisition using the sensitive enhanced product ion scan of a Q TRAP hybrid instrument. The identification of the compounds in the samples analyzed was accomplished by searching the tandem mass spectrometry (MS/MS) spectra against the library we developed, which contains electrospray ionization-MS/MS spectra of over 1,250 compounds. The multi-target screening method together with the library was included in a software program for routine screening and quantitation to achieve automated acquisition and library searching. With the help of this software application, the time for evaluation and interpretation of the results could be drastically reduced. This new multi-target screening method has been successfully applied for the analysis of postmortem and traffic offense samples as well as proficiency testing, and complements screening with immunoassays, gas chromatography-mass spectrometry, and liquid chromatography-diode-array detection. Other possible applications are analysis in clinical toxicology (for intoxication cases), in psychiatry (antidepressants and other psychoactive drugs), and in forensic toxicology (drugs and driving, workplace drug testing, oral fluid analysis, drug-facilitated sexual assault).
Method for construction of normalized cDNA libraries

Science.gov (United States)

Soares, Marcelo B.; Efstratiadis, Argiris

1998-01-01

This invention provides a method to normalize a directional cDNA library constructed in a vector that allows propagation in single-stranded circle form comprising: (a) propagating the directional cDNA library in single-stranded circles; (b) generating fragments complementary to the 3' noncoding sequence of the single-stranded circles in the library to produce partial duplexes; (c) purifying the partial duplexes; (d) melting and reassociating the purified partial duplexes to appropriate Cot; and (e) purifying the unassociated single-stranded circles, thereby generating a normalized cDNA library. This invention also provides normalized cDNA libraries generated by the above-described method and uses of the generated libraries.
Delivering a MOOC for literature searching in health libraries: evaluation of a pilot project.

Science.gov (United States)

Young, Gil; McLaren, Lisa; Maden, Michelle

2017-12-01

In an era when library budgets are being reduced, Massive Online Open Courses (MOOC's) can offer practical and viable alternatives to the delivery of costly face-to-face training courses. In this study, guest writers Gil Young from Health Care Libraries Unit - North, Lisa McLaren from Brighton and Sussex Medical School and Liverpool University PhD student Michelle Maden describe the outcomes of a funded project they led to develop a MOOC to deliver literature search training for health librarians. Funded by Health Education England, the MOOC was developed by the Library and Information Health Network North West as a pilot project that ran for six weeks. In particular, the MOOC target audience is discussed, how content was developed for the MOOC, promotion and participation, cost-effectiveness, evaluation, the impact of the MOOC and recommendations for future development. H. S. © 2017 Health Libraries Group.
Direct glycan structure determination of intact N-linked glycopeptides by low-energy collision-induced dissociation tandem mass spectrometry and predicted spectral library searching.

Science.gov (United States)

Pai, Pei-Jing; Hu, Yingwei; Lam, Henry

2016-08-31

Intact glycopeptide MS analysis to reveal site-specific protein glycosylation is an important frontier of proteomics. However, computational tools for analyzing MS/MS spectra of intact glycopeptides are still limited and not well-integrated into existing workflows. In this work, a new computational tool which combines the spectral library building/searching tool, SpectraST (Lam et al. Nat. Methods2008, 5, 873-875), and the glycopeptide fragmentation prediction tool, MassAnalyzer (Zhang et al. Anal. Chem.2010, 82, 10194-10202) for intact glycopeptide analysis has been developed. Specifically, this tool enables the determination of the glycan structure directly from low-energy collision-induced dissociation (CID) spectra of intact glycopeptides. Given a list of possible glycopeptide sequences as input, a sample-specific spectral library of MassAnalyzer-predicted spectra is built using SpectraST. Glycan identification from CID spectra is achieved by spectral library searching against this library, in which both m/z and intensity information of the possible fragmentation ions are taken into consideration for improved accuracy. We validated our method using a standard glycoprotein, human transferrin, and evaluated its potential to be used in site-specific glycosylation profiling of glycoprotein datasets from LC-MS/MS. In addition, we further applied our method to reveal, for the first time, the site-specific N-glycosylation profile of recombinant human acetylcholinesterase expressed in HEK293 cells. For maximum usability, SpectraST is developed as part of the Trans-Proteomic Pipeline (TPP), a freely available and open-source software suite for MS data analysis. Copyright © 2016 Elsevier B.V. All rights reserved.
Beyond Failure: Potentially Mitigating Failed Author Searches in the Online Library Catalog through the Use of Linked Data

Science.gov (United States)

Moulaison, Heather Lea; Stanley, Susan Nicole

2013-01-01

Linked data stores house vetted content that can supplement the information available through online library catalogs, potentially mitigating failed author searches if information about the author exists in linked data formats. In this case study, a total of 689 failed author index queries from a large Midwestern academic library's online library…
Comparison of Iranian National Medical Library with digital libraries of selected countries.

Science.gov (United States)

Zare-Farashbandi, Firoozeh; Najafi, Nayere Sadat Soleimanzade; Atashpour, Bahare

2014-01-01

The important role of information and communication technologies and their influence on methods of storing, retrieving information in digital libraries, has not only changed the meanings behind classic library activates but has also created great changes in their services. However, it seems that not all digital libraries provide their users with similar services and only some of them are successful in fulfilling their role in digital environment. The Iranian National Medical library is among those that appear to come short compared to other digital libraries around the world. By knowing the different services provided by digital libraries worldwide, one can evaluate the services provided by Iranian National Medical library. The goal of this study is a comparison between Iranian National Medical library and digital libraries of selected countries. This is an applied study and uses descriptive - survey method. The statistical population is the digital libraries around the world which were actively providing library services between October and December 2011 and were selected by using the key word "Digital Library" in Google search engine. The data-gathering tool was direct access to the websites of these digital libraries. The statistical study is descriptive and Excel software was used for data analysis and plotting of the charts. The findings showed that among the 33 digital libraries investigated worldwide, most of them provided Browse (87.87%), Search (84.84%), and Electronic information retrieval (57.57%) services. The "Help" in public services (48/48%) and "Interlibrary Loan" in traditional services (27/27%) had the highest frequency. The Iranian National Medical library provides more digital services compared to other libraries but has less classic and public services and has less than half of possible public services. Other than Iranian National Medical library, among the 33 libraries investigated, the leaders in providing different services are Library of
Engineering Bacteria to Search for Specific Concentrations of Molecules by a Systematic Synthetic Biology Design Method.

Science.gov (United States)

Tien, Shin-Ming; Hsu, Chih-Yuan; Chen, Bor-Sen

2016-01-01

Bacteria navigate environments full of various chemicals to seek favorable places for survival by controlling the flagella's rotation using a complicated signal transduction pathway. By influencing the pathway, bacteria can be engineered to search for specific molecules, which has great potential for application to biomedicine and bioremediation. In this study, genetic circuits were constructed to make bacteria search for a specific molecule at particular concentrations in their environment through a synthetic biology method. In addition, by replacing the "brake component" in the synthetic circuit with some specific sensitivities, the bacteria can be engineered to locate areas containing specific concentrations of the molecule. Measured by the swarm assay qualitatively and microfluidic techniques quantitatively, the characteristics of each "brake component" were identified and represented by a mathematical model. Furthermore, we established another mathematical model to anticipate the characteristics of the "brake component". Based on this model, an abundant component library can be established to provide adequate component selection for different searching conditions without identifying all components individually. Finally, a systematic design procedure was proposed. Following this systematic procedure, one can design a genetic circuit for bacteria to rapidly search for and locate different concentrations of particular molecules by selecting the most adequate "brake component" in the library. Moreover, following simple procedures, one can also establish an exclusive component library suitable for other cultivated environments, promoter systems, or bacterial strains.
Engineering Bacteria to Search for Specific Concentrations of Molecules by a Systematic Synthetic Biology Design Method.

Directory of Open Access Journals (Sweden)

Shin-Ming Tien

Full Text Available Bacteria navigate environments full of various chemicals to seek favorable places for survival by controlling the flagella's rotation using a complicated signal transduction pathway. By influencing the pathway, bacteria can be engineered to search for specific molecules, which has great potential for application to biomedicine and bioremediation. In this study, genetic circuits were constructed to make bacteria search for a specific molecule at particular concentrations in their environment through a synthetic biology method. In addition, by replacing the "brake component" in the synthetic circuit with some specific sensitivities, the bacteria can be engineered to locate areas containing specific concentrations of the molecule. Measured by the swarm assay qualitatively and microfluidic techniques quantitatively, the characteristics of each "brake component" were identified and represented by a mathematical model. Furthermore, we established another mathematical model to anticipate the characteristics of the "brake component". Based on this model, an abundant component library can be established to provide adequate component selection for different searching conditions without identifying all components individually. Finally, a systematic design procedure was proposed. Following this systematic procedure, one can design a genetic circuit for bacteria to rapidly search for and locate different concentrations of particular molecules by selecting the most adequate "brake component" in the library. Moreover, following simple procedures, one can also establish an exclusive component library suitable for other cultivated environments, promoter systems, or bacterial strains.
Reading for Education: the role of libraries | Dadzie | Ghana Library ...

African Journals Online (AJOL)

Reading for Education: the role of libraries. ... PROMOTING ACCESS TO AFRICAN RESEARCH. AFRICAN JOURNALS ONLINE (AJOL) · Journals · Advanced Search · USING AJOL · RESOURCES. Ghana Library Journal. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home ...
Enterprise Reference Library

Science.gov (United States)

Bickham, Grandin; Saile, Lynn; Havelka, Jacque; Fitts, Mary

2011-01-01

Introduction: Johnson Space Center (JSC) offers two extensive libraries that contain journals, research literature and electronic resources. Searching capabilities are available to those individuals residing onsite or through a librarian s search. Many individuals have rich collections of references, but no mechanisms to share reference libraries across researchers, projects, or directorates exist. Likewise, information regarding which references are provided to which individuals is not available, resulting in duplicate requests, redundant labor costs and associated copying fees. In addition, this tends to limit collaboration between colleagues and promotes the establishment of individual, unshared silos of information The Integrated Medical Model (IMM) team has utilized a centralized reference management tool during the development, test, and operational phases of this project. The Enterprise Reference Library project expands the capabilities developed for IMM to address the above issues and enhance collaboration across JSC. Method: After significant market analysis for a multi-user reference management tool, no available commercial tool was found to meet this need, so a software program was built around a commercial tool, Reference Manager 12 by The Thomson Corporation. A use case approach guided the requirements development phase. The premise of the design is that individuals use their own reference management software and export to SharePoint when their library is incorporated into the Enterprise Reference Library. This results in a searchable user-specific library application. An accompanying share folder will warehouse the electronic full-text articles, which allows the global user community to access full -text articles. Discussion: An enterprise reference library solution can provide a multidisciplinary collection of full text articles. This approach improves efficiency in obtaining and storing reference material while greatly reducing labor, purchasing and
Research Library

Science.gov (United States)

Los Alamos National Laboratory Research Library Search Site submit Contact Us | Remote Access Standards Theses/Dissertations Research Help Subject Guides Library Training Video Tutorials Alerts Research Library: delivering essential knowledge services for national security sciences since 1947 Los
Design of combinatorial libraries for the exploration of virtual hits from fragment space searches with LoFT.

Science.gov (United States)

Lessel, Uta; Wellenzohn, Bernd; Fischer, J Robert; Rarey, Matthias

2012-02-27

A case study is presented illustrating the design of a focused CDK2 library. The scaffold of the library was detected by a feature trees search in a fragment space based on reactions from combinatorial chemistry. For the design the software LoFT (Library optimizer using Feature Trees) was used. The special feature called FTMatch was applied to restrict the parts of the queries where the reagents are permitted to match. This way a 3D scoring function could be simulated. Results were compared with alternative designs by GOLD docking and ROCS 3D alignments.
The Personal Virtual Library

CERN Document Server

Le Meur, Jean-Yves

1998-01-01

Looking for "library" in the usual search engines of the World Wide Web gives: "Infoseek found 3,593,126 pages containing the word library" and it nicely proposes: "Search only within these 3,59 3,126 pages ?" "Yahoo! Found 1299 categories and 8669 sites for library" "LycOs: 1-10 von 512354 relevanten Ergebnissen" "AltaVista: About 14830527 documents match your query" and at the botto m: "Word count: library: 15466897" ! Excite: Top 10 matches and it does not say how many can be browsed... "Library" on the World Wide Web is really popular. At least fiveteen million pages ar e supposed to contain this word. Half of them may have disappeared by now but one more hit will be added once the search robots will have indexed this document ! The notion of Personal Library i s a modest attempt, in a small environment like a library, to give poor users lost in cyber-libraries the opportunity to keep their own private little shelves - virtually. In this paper, we will l ook at the usual functionalities of library systems...
Library Computing

Science.gov (United States)

Library Computing, 1985

1985-01-01

Special supplement to "Library Journal" and "School Library Journal" covers topics of interest to school, public, academic, and special libraries planning for automation: microcomputer use, readings in automation, online searching, databases of microcomputer software, public access to microcomputers, circulation, creating a…
Evaluating ranking methods on heterogeneous digital library collections

CERN Document Server

Canévet, Olivier; Marian, Ludmila; Chonavel, Thierry

In the frame of research in particle physics, CERN has been developing its own web-based software /Invenio/ to run the digital library of all the documents related to CERN and fundamental physics. The documents (articles, photos, news, thesis, ...) can be retrieved through a search engine. The results matching the query of the user can be displayed in several ways: sorted by latest first, author, title and also ranked by word similarity. The purpose of this project is to study and implement a new ranking method in Invenio: distributed-ranking (D-Rank). This method aims at aggregating several ranking scores coming from different ranking methods into a new score. In addition to query-related scores such as word similarity, the goal of the work is to take into account non-query-related scores such as citations, journal impact factor and in particular scores related to the document access frequency in the database. The idea is that for two equally query-relevant documents, if one has been more downloaded for inst...
TRANSFORMATION OF INNOVATIVE AND METHODICAL ACTIVITY LIBRARY OF THE UNIVERSITY

Directory of Open Access Journals (Sweden)

О. О. Скаченко

2015-09-01

Full Text Available The purpose of our article is the analysis of innovative and methodical activity of university libraries which develop as information centers today. The subject of research is methodical, publishing and innovative activity of Scientific Library of the Kiev national university of culture and arts. We observe process of introduction of technological innovations in library service that allows improving quality of the services provided to the reader by library. New actual projects are developed, cultural and educational and information services extend, work methods improve. Also, the structure of library is improved – there are new sectors. The main finding of the work consists in systematization of various aspects and the directions of innovative activity of library. The research findings have the practical value for library workers, teachers of university, students, library users, and also for anyone who is interested in library science.

State Virtual Libraries

Science.gov (United States)

Pappas, Marjorie L.

2003-01-01

Virtual library? Electronic library? Digital library? Online information network? These all apply to the growing number of Web-based resource collections managed by consortiums of state library entities. Some, like "INFOhio" and "KYVL" ("Kentucky Virtual Library"), have been available for a few years, but others are just starting. Searching for…
The Searchbench - Combining Sentence-semantic, Full-text and Bibliographic Search in Digital Libraries

Directory of Open Access Journals (Sweden)

Ulrich Schäfer

2013-02-01

Full Text Available We describe a novel approach to precise searching in the full content of digital libraries. The Searchbench (for search workbench is based on sentence-wise syntactic and semantic natural language processing (NLP of both born-digital and scanned publications in PDF format. The term born-digital means natively digital, i.e. prepared electronically using typesetting systems such as LaTeX, OpenOffice, and the like. In the Searchbench, queries can be formulated as (possibly underspecified statements, consisting of simple subject-predicate-object constructs such as ‘algorithm improves word alignment’. This reduces the number of false hits in large document collections when the search words happen to appear close to each other, but are not semantically related. The method also abstracts from passive voice and predicate synonyms. Moreover, negated statements can be excluded from the search results, and negated antonym predicates again count as synonyms (e.g. not include = exclude.In the Searchbench, a sentence-semantic search can be combined with search filters for classical full-text, bibliographic metadata and automatically computed domain terms. Auto-suggest fields facilitate text input. Queries can be bookmarked or emailed. Furthermore, a novel citation browser in the Searchbench allows graphical navigation in citation networks. These have been extracted automatically from metadata and paper texts. The citation browser displays short phrases from citation sentences at the edges in the citation graph and thus allows students and researchers to quickly browse publications and immerse into a new research field. By clicking on a citation edge, the original citation sentence is shown in context, and optionally also in the original PDF layout.To showcase the usefulness of our research, we have a applied it to a collection of currently approx. 25,000 open access research papers in the field of computational linguistics and language technology, the ACL
Combining history of medicine and library instruction: an innovative approach to teaching database searching to medical students.

Science.gov (United States)

Timm, Donna F; Jones, Dee; Woodson, Deidra; Cyrus, John W

2012-01-01

Library faculty members at the Health Sciences Library at the LSU Health Shreveport campus offer a database searching class for third-year medical students during their surgery rotation. For a number of years, students completed "ten-minute clinical challenges," but the instructors decided to replace the clinical challenges with innovative exercises using The Edwin Smith Surgical Papyrus to emphasize concepts learned. The Surgical Papyrus is an online resource that is part of the National Library of Medicine's "Turning the Pages" digital initiative. In addition, vintage surgical instruments and historic books are displayed in the classroom to enhance the learning experience.
Multi-level computational methods for interdisciplinary research in the HathiTrust Digital Library.

Science.gov (United States)

Murdock, Jaimie; Allen, Colin; Börner, Katy; Light, Robert; McAlister, Simon; Ravenscroft, Andrew; Rose, Robert; Rose, Doori; Otsuka, Jun; Bourget, David; Lawrence, John; Reed, Chris

2017-01-01

We show how faceted search using a combination of traditional classification systems and mixed-membership topic models can go beyond keyword search to inform resource discovery, hypothesis formulation, and argument extraction for interdisciplinary research. Our test domain is the history and philosophy of scientific work on animal mind and cognition. The methods can be generalized to other research areas and ultimately support a system for semi-automatic identification of argument structures. We provide a case study for the application of the methods to the problem of identifying and extracting arguments about anthropomorphism during a critical period in the development of comparative psychology. We show how a combination of classification systems and mixed-membership models trained over large digital libraries can inform resource discovery in this domain. Through a novel approach of "drill-down" topic modeling-simultaneously reducing both the size of the corpus and the unit of analysis-we are able to reduce a large collection of fulltext volumes to a much smaller set of pages within six focal volumes containing arguments of interest to historians and philosophers of comparative psychology. The volumes identified in this way did not appear among the first ten results of the keyword search in the HathiTrust digital library and the pages bear the kind of "close reading" needed to generate original interpretations that is the heart of scholarly work in the humanities. Zooming back out, we provide a way to place the books onto a map of science originally constructed from very different data and for different purposes. The multilevel approach advances understanding of the intellectual and societal contexts in which writings are interpreted.
Project GRACE A grid based search tool for the global digital library

CERN Document Server

Scholze, Frank; Vigen, Jens; Prazak, Petra; The Seventh International Conference on Electronic Theses and Dissertations

2004-01-01

The paper will report on the progress of an ongoing EU project called GRACE - Grid Search and Categorization Engine (http://www.grace-ist.org). The project participants are CERN, Sheffield Hallam University, Stockholm University, Stuttgart University, GL 2006 and Telecom Italia. The project started in 2002 and will finish in 2005, resulting in a Grid based search engine that will search across a variety of content sources including a number of electronic thesis and dissertation repositories. The Open Archives Initiative (OAI) is expanding and is clearly an interesting movement for a community advocating open access to ETD. However, the OAI approach alone may not be sufficiently scalable to achieve a truly global ETD Digital Library. Many universities simply offer their collections to the world via their local web services without being part of any federated system for archiving and even those dissertations that are provided with OAI compliant metadata will not necessarily be picked up by a centralized OAI Ser...
Building and evaluating an informatics tool to facilitate analysis of a biomedical literature search service in an academic medical center library.

Science.gov (United States)

Hinton, Elizabeth G; Oelschlegel, Sandra; Vaughn, Cynthia J; Lindsay, J Michael; Hurst, Sachiko M; Earl, Martha

2013-01-01

This study utilizes an informatics tool to analyze a robust literature search service in an academic medical center library. Structured interviews with librarians were conducted focusing on the benefits of such a tool, expectations for performance, and visual layout preferences. The resulting application utilizes Microsoft SQL Server and .Net Framework 3.5 technologies, allowing for the use of a web interface. Customer tables and MeSH terms are included. The National Library of Medicine MeSH database and entry terms for each heading are incorporated, resulting in functionality similar to searching the MeSH database through PubMed. Data reports will facilitate analysis of the search service.
FRBRization of a Library Catalog: Better Collocation of Records, Leading to Enhanced Search, Retrieval, and Display

Directory of Open Access Journals (Sweden)

Timothy J. Dickey

2008-03-01

Full Text Available The Functional Requirements for Bibliographic Records (FRBR’s hierarchical system defines families of bibliographic relationship between records and collocates them better than most extant bibliographic systems. Certain library materials (especially audio-visual formats pose notable challenges to search and retrieval; the first benefits of a FRBRized system would be felt in music libraries, but research already has proven its advantages for fine arts, theology, and literature—the bulk of the non-science, technology, and mathematics collections. This report will summarize the benefits of FRBR to nextgeneration library catalogs and OPACs, and will review the handful of ILS and catalog systems currently operating with its theoretical structure.
ENSURING HIGH-QUALITY THEMATIC SEARCH IN THE ELECTRONIC CATALOGUE (FROM EXPERIENCE OF THE SCIENTIFIC LIBRARY OF THE ODESSA I. I. MECHNIKOV NATIONAL UNIVERSITY

Directory of Open Access Journals (Sweden)

Т. М. Бикова

2015-09-01

Full Text Available The purpose of our article is the description of electronic subject analysis of documents and creation of the dictionary of subject headings in the electronic catalog. The subject of the research is the electronic catalog of the Scientific Library of the Odessa I. I. Mechnikov National University. The purpose of work is development of a technique of edition of sections of the thesaurus. In 2012 the Scientific Library of the Odessa I. I. Mechnikov National University has moved to the new software ABIS Absotheque Unicode which allowed to improve (to simplify search in the electronic catalog. The department of scientific processing and the organization of catalogs carried out edition of sections of the thesaurus, instructions are formed, and the edition technique is developed, process of editing is studied. Drawing up the thesaurus of subject headings is carried out by means of loans from full tables BBC for scientific libraries. Even if he has no clear idea and profound knowledge of a search subject, simplifies correctly made subject headings for the reader and does more effective thematic search. The main finding of the work is in need of continuous editing subject headings that simplifies and does more comfortable search in the electronic catalog for the user of library. The research findings have the practical value for employees of libraries.
Libraries in Online Elementary Schools: A Mixed-Methods Study

Science.gov (United States)

Hibbard, Laura; Franklin, Teresa

2015-01-01

School libraries serve an important role; however, elementary students who attend schools online typically do not have a school library. This study followed an online school's inaugural year in instituting a library. A mixed methods approach examined data from focus groups, interviews, surveys, library-use records and oral reading fluency scores.…
The Weaknesses of Full-Text Searching

Science.gov (United States)

Beall, Jeffrey

2008-01-01

This paper provides a theoretical critique of the deficiencies of full-text searching in academic library databases. Because full-text searching relies on matching words in a search query with words in online resources, it is an inefficient method of finding information in a database. This matching fails to retrieve synonyms, and it also retrieves…
Flexible and scalable digital library search

NARCIS (Netherlands)

H.E. Blok; M.A. Windhouwer (Menzo); R. van Zwol; M. Petkovic; P.M.G. Apers; M.L. Kersten (Martin); W. Jonker

2001-01-01

textabstractThe everlasting search for new methods to explore the Inter- or Intranet is still going on. In this demo we present the combined effort of the AMIS and DMW research projects, each covering significant parts of this problem. The contribution of this demo is twofold. Firstly, we
Quality evaluation of tandem mass spectral libraries.

Science.gov (United States)

Oberacher, Herbert; Weinmann, Wolfgang; Dresen, Sebastian

2011-06-01

Tandem mass spectral libraries are gaining more and more importance for the identification of unknowns in different fields of research, including metabolomics, forensics, toxicology, and environmental analysis. Particularly, the recent invention of reliable, robust, and transferable libraries has increased the general acceptance of these tools. Herein, we report on results obtained from thorough evaluation of the match reliabilities of two tandem mass spectral libraries: the MSforID library established by the Oberacher group in Innsbruck and the Weinmann library established by the Weinmann group in Freiburg. Three different experiments were performed: (1) Spectra of the libraries were searched against their corresponding library after excluding either this single compound-specific spectrum or all compound-specific spectra prior to searching; (2) the libraries were searched against each other using either library as reference set or sample set; (3) spectra acquired on different mass spectrometric instruments were matched to both libraries. Almost 13,000 tandem mass spectra were included in this study. The MSforID search algorithm was used for spectral matching. Statistical evaluation of the library search results revealed that principally both libraries enable the sensitive and specific identification of compounds. Due to higher mass accuracy of the QqTOF compared with the QTrap instrument, matches to the MSforID library were more reliable when comparing spectra with both libraries. Furthermore, only the MSforID library was shown to be efficiently transferable to different kinds of tandem mass spectrometers, including "tandem-in-time" instruments; this is due to the coverage of a large range of different collision energy settings-including the very low range-which is an outstanding characteristics of the MSforID library.
Generating "fragment-based virtual library" using pocket similarity search of ligand-receptor complexes.

Science.gov (United States)

Khashan, Raed S

2015-01-01

As the number of available ligand-receptor complexes is increasing, researchers are becoming more dedicated to mine these complexes to aid in the drug design and development process. We present free software which is developed as a tool for performing similarity search across ligand-receptor complexes for identifying binding pockets which are similar to that of a target receptor. The search is based on 3D-geometric and chemical similarity of the atoms forming the binding pocket. For each match identified, the ligand's fragment(s) corresponding to that binding pocket are extracted, thus forming a virtual library of fragments (FragVLib) that is useful for structure-based drug design. The program provides a very useful tool to explore available databases.
KVK - a Meta Catalog of Libraries

Directory of Open Access Journals (Sweden)

Michael W. Mönnich

2001-07-01

Full Text Available Over the past years, the majority of libraries worldwide implemented interfaces to allow users to access to their bibliographic databases through the WWW. Usually these interfaces consist of HTML-pages with an embedded FORMS template where the search terms are entered. Thus for the first time it was made possible for the user to access almost every library using only one software: the WWW browser. However, if the user has to search more than one library catalog, e.g. when searching literature for a PhD thesis, he has to access a multitude of catalogs deal with different search forms, different search syntaxes, wildcards etc. This is the case especially for users in Germany. Faced with this situation in 1996, our team at the university library of Karlsruhe came up with the idea to create a virtual catalog enabling our library patrons to search several catalogs simultaneously. The idea was inspired by the successful introduction of meta search engines like metacrawler which perform the same function with internet search engines. So why not try to do it with library catalogs? The idea was discussed, and with support from the faculty of computer science, a prototype was built in July 1996. It proved surprisingly easy to do, so we included not only union catalogs but also bookshops. The meta catalog showed so much potential that we decided not to limit access to our local library patrons but to offer it as a service to the internet community as Karlsruher Virtueller Katalog (KVK, Karlsruhe Virtual Catalog. Once the KVK was announced in several mailing list, the usage peaked within a few weeks and has continued to do so.
Through the Students’ Lens: Photographic Methods for Research in Library Spaces

Directory of Open Access Journals (Sweden)

Shailoo Bedi

2017-06-01

Full Text Available Abstract Objective – As librarians and researchers, we are deeply curious about how our library users navigate and experience our library spaces. Although we have some data about users’ experiences and wayfinding strategies at our libraries, including anecdotal evidence, statistics, surveys, and focus group discussions, we lacked more in-depth information that reflected students’ real-time experiences as they move through our library spaces. Our objective is to address that gap by using photographic methods for studying library spaces. Methods – We present two studies conducted in two academic libraries that used participant-driven photo-elicitation (PDPE methods. Described simply, photo-elicitation methods involve the use of photographs as discussion prompts in interviews. In both studies presented here, we asked participants to take photographs that reflected their experiences using and navigating our library spaces. We then met with participants for an interview using their photos as prompts to discuss their experiences. Results – Our analysis of students’ photos and interviews provided rich descriptions of student experiences in library spaces. This analysis resulted in new insights into the ways that students navigate the library as well as the ways that signage, furniture, technology, and artwork in the library can shape student experiences in library spaces. The results have proven productive in generating answers to our research questions and supporting practical improvements to our libraries. Additionally, when comparing the results from our two studies we identified the importance of detailed spatial references for understanding student experiences in library spaces, which has implications beyond our institutions. Conclusion – We found that photographic methods were very productive in helping us to understand library users’ experiences and supporting decision-making related to library spaces. In addition, engaging with
Monte Carlo Library Least Square (MCLLS) Method for Multiple Radioactive Particle Tracking in BPR

Science.gov (United States)

Wang, Zhijian; Lee, Kyoung; Gardner, Robin

2010-03-01

In This work, a new method of radioactive particles tracking is proposed. An accurate Detector Response Functions (DRF's) was developed from MCNP5 to generate library for NaI detectors with a significant speed-up factor of 200. This just make possible for the idea of MCLLS method which is used for locating and tracking the radioactive particle in a modular Pebble Bed Reactor (PBR) by searching minimum Chi-square values. The method was tested to work pretty good in our lab condition with a six 2" X 2" NaI detectors array only. This method was introduced in both forward and inverse ways. A single radioactive particle tracking system with three collimated 2" X 2" NaI detectors is used for benchmark purpose.
Search without Boundaries Using Simple APIs

Science.gov (United States)

Tong, Qi

2009-01-01

The U.S. Geological Survey (USGS) Library, where the author serves as the digital services librarian, is increasingly challenged to make it easier for users to find information from many heterogeneous information sources. Information is scattered throughout different software applications (i.e., library catalog, federated search engine, link resolver, and vendor websites), and each specializes in one thing. How could the library integrate the functionalities of one application with another and provide a single point of entry for users to search across? To improve the user experience, the library launched an effort to integrate the federated search engine into the library's intranet website. The result is a simple search box that leverages the federated search engine's built-in application programming interfaces (APIs). In this article, the author describes how this project demonstrated the power of APIs and their potential to be used by other enterprise search portals inside or outside of the library.
Combined use of ESI-QqTOF-MS and ESI-QqTOF-MS/MS with mass-spectral library search for qualitative analysis of drugs.

Science.gov (United States)

Pavlic, Marion; Libiseller, Kathrin; Oberacher, Herbert

2006-09-01

The potential of the combined use of ESI-QqTOF-MS and ESI-QqTOF-MS/MS with mass-spectral library search for the identification of therapeutic and illicit drugs has been evaluated. Reserpine was used for standardizing experimental conditions and for characterization of the performance of the applied mass spectrometric system. Experiments revealed that because of the mass accuracy, the stability of calibration, and the reproducibility of fragmentation, the QqTOF mass spectrometer is an appropriate platform for establishment of a tandem-mass-spectral library. Three-hundred and nineteen substances were used as reference samples to build the spectral library. For each reference compound, product-ion spectra were acquired at ten different collision-energy values between 5 eV and 50 eV. For identification of unknown compounds, a library search algorithm was developed. The closeness of matching between a measured product-ion spectrum and a spectrum stored in the library was characterized by a value called "match probability", which took into account the number of matched fragment ions, the number of fragment ions observed in the two spectra, and the sum of the intensity differences calculated for matching fragments. A large value for the match probability indicated a close match between the measured and the reference spectrum. A unique feature of the library search algorithm-an implemented spectral purification option-enables characterization of multi-contributor fragment-ion spectra. With the aid of this software feature, substances comprising only 1.0% of the total amount of binary mixtures were unequivocally assigned, in addition to the isobaric main contributors. The spectral library was successfully applied to the characterization of 39 forensic casework samples.
Nigerian Libraries: Advanced Search

African Journals Online (AJOL)

Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...
Potential Fit to the Department Outweighs Professional Criteria in the Hiring Process in Academic Libraries. A Review of: Wang, Z. & Guarria, C. (2010. Unlocking the mystery: What academic library search committees look for in filling faculty positions. Technical Services Quarterly, 27, 66–86.

Directory of Open Access Journals (Sweden)

Yvonne Hultman Özek

2010-12-01

Full Text Available Objective – To identify key factors affecting the probability of obtaining an interview and being hired for an academic library position.Design – An online survey was distributed via the following electronic mail lists: ACRL, LITA, COLLIB, METRO, ACQNET, COLLDV, ULS, EQUILIBR, and ALF. The questionnaire was posted via StudentVoice, an assessment survey provider.Setting – Academic libraries in the United States.Subjects – The 242 academic library search committees that responded to the online survey.Methods – The authors reviewed the literature on the hiring process in academic libraries. A questionnaire for an online survey was developed. The instrument contained closed questions with the option to add comments. The survey was available for completion June 3 to June 15, 2008.Main Results – Skills and performance of job requirements were rated as the most important criteria by 90% of the 242 academic library search committees that responded to the survey. Previous academic library experience was rated as essential by 38%. The findings also showed that committees are positive towards hiring recent graduates, and over 90% check references. In addition, 75% of the respondents emphasized the importance of skills in bibliographic instruction (BI, particularly when choosing staff for public services.Furthermore, of the 242 respondents, 47.52%, answering the corresponding question indicated that a relevant cover letter, correct spelling, and declaration of the candidate’s activities over all time periods are crucial aspects.Those in favour of using a weighted scoring system, 37% of 218 respondents, felt that it served as a tool to level the playing field for gathering accurate information, and it also helped to improve the efficiency as well as speed of the hiring process. However, 62.84% of the respondents commented that a weighted scoring system is too prescribed, and some universities did not allow the use of this method. Of 218

The impact of PICO as a search strategy tool on literature search quality

DEFF Research Database (Denmark)

Eriksen, Mette Brandt; Frandsen, Tove Faber

2018-01-01

Objective: This review aimed to determine, if the use of the PICO model (Patient Intervention Comparison Outcome) as a search strategy tool affects the quality of the literature search. Methods: A comprehensive literature search was conducted in: PubMed, Embase, CINAHL, PsycInfo, Cochrane Library...... and three studies were included, data was extracted, risk of bias was assessed and a qualitative analysis was conducted. The included studies compared PICO to PIC or link to related articles in PubMed; PICOS and SPIDER. One study compared PICO to unguided searching. Due to differences in intervention...
Fee-based services in sci-tech libraries

CERN Document Server

Mount, Ellis

2013-01-01

This timely and important book explores how fee-based services have developed in various types of sci-tech libraries. The authoritative contributors focus on the current changing financial aspects of the sci-tech library operation and clarify for the reader how these changes have brought about conditions in which traditional methods of funding are no longer adequate. What new options are open and how they are best being applied in today's sci-tech libraries is fully and clearly explained and illustrated. Topics explored include cost allocation and cost recovery, fees for computer searching, an
Pre-Service Teachers' Use of Library Databases: Some Insights

Science.gov (United States)

Lamb, Janeen; Howard, Sarah; Easey, Michael

2014-01-01

The aim of this study is to investigate if providing mathematics education pre-service teachers with animated library tutorials on library and database searches changes their searching practices. This study involved the completion of a survey by 138 students and seven individual interviews before and after library search demonstration videos were…
Many Libraries Have Gone to Federated Searching to Win Users Back from Google. Is It Working?

Science.gov (United States)

King, Douglas

2008-01-01

In the last issue, this journal asked a question on many librarians' minds, and it was pleased with the depth and variety of responses. As suggested by this journal editorial board member Oliver Pesch, readers were asked, "Many libraries have gone to federated searching to win users back from Google. Is it working?" Respondents approached the…
An Exploration of Retrieval-Enhancing Methods for Integrated Search in a Digital Library

DEFF Research Database (Denmark)

Sørensen, Diana Ransgaard; Bogers, Toine; Larsen, Birger

2012-01-01

Integrated search is defined as searching across different document types and representations simultaneously, with the goal of presenting the user with a single ranked result list containing the optimal mix of document types. In this paper, we compare various approaches to integrating three diffe...
All roads lead to Rome - New search methods for the optimal triangulation problem

Czech Academy of Sciences Publication Activity Database

Ottosen, T. J.; Vomlel, Jiří

2012-01-01

Roč. 53, č. 9 (2012), s. 1350-1366 ISSN 0888-613X R&D Projects: GA MŠk 1M0572; GA ČR GEICC/08/E010; GA ČR GA201/09/1891 Grant - others:GA MŠk(CZ) 2C06019 Institutional support: RVO:67985556 Keywords : Bayesian networks * Optimal triangulation * Probabilistic inference * Cliques in a graph Subject RIV: BD - Theory of Information Impact factor: 1.729, year: 2012 http://library.utia.cas.cz/separaty/2012/MTR/vomlel-all roads lead to rome - new search methods for the optimal triangulation problem.pdf
Using Digital Libraries Non-Visually: Understanding the Help-Seeking Situations of Blind Users

Science.gov (United States)

Xie, Iris; Babu, Rakesh; Joo, Soohyung; Fuller, Paige

2015-01-01

Introduction: This study explores blind users' unique help-seeking situations in interacting with digital libraries. In particular, help-seeking situations were investigated at both the physical and cognitive levels. Method: Fifteen blind participants performed three search tasks, including known- item search, specific information search, and…
Bayesian approach to peak deconvolution and library search for high resolution gas chromatography - Mass spectrometry.

Science.gov (United States)

Barcaru, A; Mol, H G J; Tienstra, M; Vivó-Truyols, G

2017-08-29

A novel probabilistic Bayesian strategy is proposed to resolve highly coeluting peaks in high-resolution GC-MS (Orbitrap) data. Opposed to a deterministic approach, we propose to solve the problem probabilistically, using a complete pipeline. First, the retention time(s) for a (probabilistic) number of compounds for each mass channel are estimated. The statistical dependency between m/z channels was implied by including penalties in the model objective function. Second, Bayesian Information Criterion (BIC) is used as Occam's razor for the probabilistic assessment of the number of components. Third, a probabilistic set of resolved spectra, and their associated retention times are estimated. Finally, a probabilistic library search is proposed, computing the spectral match with a high resolution library. More specifically, a correlative measure was used that included the uncertainties in the least square fitting, as well as the probability for different proposals for the number of compounds in the mixture. The method was tested on simulated high resolution data, as well as on a set of pesticides injected in a GC-Orbitrap with high coelution. The proposed pipeline was able to detect accurately the retention times and the spectra of the peaks. For our case, with extremely high coelution situation, 5 out of the 7 existing compounds under the selected region of interest, were correctly assessed. Finally, the comparison with the classical methods of deconvolution (i.e., MCR and AMDIS) indicates a better performance of the proposed algorithm in terms of the number of correctly resolved compounds. Copyright © 2017 Elsevier B.V. All rights reserved.
The Library Macintosh at SCIL [Small Computers in Libraries]'88.

Science.gov (United States)

Valauskas, Edward J.; And Others

1988-01-01

The first of three papers describes the role of Macintosh workstations in a library. The second paper explains why the Macintosh was selected for end-user searching in an academic library, and the third discusses advantages and disadvantages of desktop publishing for librarians. (8 references) (MES)
INTERACTION OF SEARCH CAPABILITIES OF ELECTRONIC AND TRADITIONAL (CARD CATALOGS

Directory of Open Access Journals (Sweden)

Л. В. Головко

2017-10-01

Full Text Available Purpose. Interaction of search capabilities of electronic and traditional (card catalogs. Subject: search capabilities of electronic and traditional (card catalogs and their interaction. Goal: Creating efficient search system for library information services, updating and improving the information retrieval system. To reach this goal, following tasks are set: – to determine the possibility of parallel functioning of electronic and traditional card catalogs, and to reveal the interaction of their search capabilities by conducting a survey via questionnaire titled «Interaction of search capabilities of electronic and traditional (card catalogs»; – to find out which search systems are preferred by users; – to estimate the actual condition of search capabilities of electronic and traditional (card catalogs in the library. Methodology. On various stages of the survey the following methods were used: analysis and synthesis, comparison, generalization, primary sources search; sociological method (survey. These methods allowed determining, processing and ana lyzing the whole complex of available sources, which became an important factor of research objectivity. Finding. Survey results allowed us to analyze the dynamics of changes, new needs of the readers, and to make a decision regarding the quality improvement of information search services. Practical value. Creating a theoretical foundation for implementation of set tasks is the practical value of the acquired findings. Conclusions and results of the research can be used in university students’, postgraduates’ and professors’ information search activities. Certain results of the research are used and implemented in practice of the library of Kryvyi Rih State Pedagogical University, namely at workshops on the basics of information culture (using bibliographic reference unit, information search by key words, authors and titles via electronic catalogue. Guides for users were created. Duty
Evidence Based Management as a Tool for Special Libraries

Directory of Open Access Journals (Sweden)

Bill Fisher

2007-12-01

Full Text Available Objective ‐ To examine the evidence based management literature, as an example of evidence based practice, and determine how applicable evidence based management might be in the special library environment. Methods ‐ Recent general management literature and the subject‐focused literature of evidence based management were reviewed; likewise recent library/information science management literature and the subject‐focused literature of evidence based librarianshipwere reviewed to identify relevant examples of the introduction and use of evidence based practice in organizations. Searches were conducted in major business/management databases, major library/information science databases, and relevant Web sites, blogs and wikis. Citation searches on key articles and follow‐up searches on cited references were also conducted. Analysis of the retrieved literature was conducted to find similarities and/or differences between the management literature and the library/information scienceliterature, especially as it related to special libraries.Results ‐ The barriers to introducing evidence based management into most organizations were found to apply to many special libraries and are similar to issues involved with evidence based practice in librarianship in general. Despite these barriers, a set of resources to assist special librarians in accessing research‐based information to help them use principles of evidence based management is identified.Conclusion ‐ While most special librarians are faced with a number of barriers to using evidence based management, resources do exist to help overcome these obstacles.
Slovene specialized text corpus of Library and Information Science – An advanced lexicographic tool for library terminology research

OpenAIRE

Kanič, Ivan

2013-01-01

To support the research in the field of library and information science terminology and dictionary construction in Slovene language a specialized text corpus has been designed and constructed. The corpus has reached 3,6 million words extracted from 625 Slovene technical and scientific texts of the field. It supports a variety of specialized search methods, display of search results, and their statistic computation. The web based application is in open public access.
The Library as Search Engine

Science.gov (United States)

Chronicle of Higher Education, 2007

2007-01-01

This article presents a Technology Forum that focuses on online archives and their role in academe. The forum brought together Daniel Greenstein, associate vice provost for scholarly information and university librarian at the California Digital Library of the University of California; Adam Smith, group business-product manager for the Google Book…
The Use of OPAC in a Large Academic Library: A Transactional Log Analysis Study of Subject Searching

Science.gov (United States)

Villen-Rueda, Luis; Senso, Jose A.; de Moya-Anegon, Felix

2007-01-01

The analysis of user searches in catalogs has been the topic of research for over four decades, involving numerous studies and diverse methodologies. The present study looks at how different types of users effect queries in the catalog of a university library. For this purpose, we analyzed log files to determine which was the most frequent type of…
Methods library of embedded R functions at Statistics Norway

Directory of Open Access Journals (Sweden)

Øyvind Langsrud

2017-11-01

Full Text Available Statistics Norway is modernising the production processes. An important element in this work is a library of functions for statistical computations. In principle, the functions in such a methods library can be programmed in several languages. A modernised production environment demand that these functions can be reused for different statistics products, and that they are embedded within a common IT system. The embedding should be done in such a way that the users of the methods do not need to know the underlying programming language. As a proof of concept, Statistics Norway soon has established a methods library offering a limited number of methods for macro-editing, imputation and confidentiality. This is done within an area of municipal statistics with R as the only programming language. This paper presents the details and experiences from this work. The problem of fitting real word applications to simple and strict standards is discussed and exemplified by the development of solutions to regression imputation and table suppression.
A novel method of providing a library of n-mers or biopolymers

DEFF Research Database (Denmark)

2012-01-01

The present invention relates to a method of providing a library of n-mer sequences, wherein the library is composed of an n-mer sequence. Also the invention concerns a method of providing a library of biopolymer sequences having one or more n-mers in common. Further provided are specific primers...
Methods for the preparation of large quantities of complex single-stranded oligonucleotide libraries.

Science.gov (United States)

Murgha, Yusuf E; Rouillard, Jean-Marie; Gulari, Erdogan

2014-01-01

Custom-defined oligonucleotide collections have a broad range of applications in fields of synthetic biology, targeted sequencing, and cytogenetics. Also, they are used to encode information for technologies like RNA interference, protein engineering and DNA-encoded libraries. High-throughput parallel DNA synthesis technologies developed for the manufacture of DNA microarrays can produce libraries of large numbers of different oligonucleotides, but in very limited amounts. Here, we compare three approaches to prepare large quantities of single-stranded oligonucleotide libraries derived from microarray synthesized collections. The first approach, alkaline melting of double-stranded PCR amplified libraries with a biotinylated strand captured on streptavidin coated magnetic beads results in little or no non-biotinylated ssDNA. The second method wherein the phosphorylated strand of PCR amplified libraries is nucleolyticaly hydrolyzed is recommended when small amounts of libraries are needed. The third method combining in vitro transcription of PCR amplified libraries to reverse transcription of the RNA product into single-stranded cDNA is our recommended method to produce large amounts of oligonucleotide libraries. Finally, we propose a method to remove any primer binding sequences introduced during library amplification.
Children's Search Engines from an Information Search Process Perspective.

Science.gov (United States)

Broch, Elana

2000-01-01

Describes cognitive and affective characteristics of children and teenagers that may affect their Web searching behavior. Reviews literature on children's searching in online public access catalogs (OPACs) and using digital libraries. Profiles two Web search engines. Discusses some of the difficulties children have searching the Web, in the…
PMD2HD--a web tool aligning a PubMed search results page with the local German Cancer Research Centre library collection.

Science.gov (United States)

Bohne-Lang, Andreas; Lang, Elke; Taube, Anke

2005-06-27

Web-based searching is the accepted contemporary mode of retrieving relevant literature, and retrieving as many full text articles as possible is a typical prerequisite for research success. In most cases only a proportion of references will be directly accessible as digital reprints through displayed links. A large number of references, however, have to be verified in library catalogues and, depending on their availability, are accessible as print holdings or by interlibrary loan request. The problem of verifying local print holdings from an initial retrieval set of citations can be solved using Z39.50, an ANSI protocol for interactively querying library information systems. Numerous systems include Z39.50 interfaces and therefore can process Z39.50 interactive requests. However, the programmed query interaction command structure is non-intuitive and inaccessible to the average biomedical researcher. For the typical user, it is necessary to implement the protocol within a tool that hides and handles Z39.50 syntax, presenting a comfortable user interface. PMD2HD is a web tool implementing Z39.50 to provide an appropriately functional and usable interface to integrate into the typical workflow that follows an initial PubMed literature search, providing users with an immediate asset to assist in the most tedious step in literature retrieval, checking for subscription holdings against a local online catalogue. PMD2HD can facilitate literature access considerably with respect to the time and cost of manual comparisons of search results with local catalogue holdings. The example presented in this article is related to the library system and collections of the German Cancer Research Centre. However, the PMD2HD software architecture and use of common Z39.50 protocol commands allow for transfer to a broad range of scientific libraries using Z39.50-compatible library information systems.
XML in Libraries.

Science.gov (United States)

Tennant, Roy, Ed.

This book presents examples of how libraries are using XML (eXtensible Markup Language) to solve problems, expand services, and improve systems. Part I contains papers on using XML in library catalog records: "Updating MARC Records with XMLMARC" (Kevin S. Clarke, Stanford University) and "Searching and Retrieving XML Records via the…

Demonstrating the financial impact of clinical libraries: a systematic review.

Science.gov (United States)

Madden, Anne; Collins, Pamela; McGowan, Sondhaya; Stevenson, Paul; Castelli, David; Hyde, Loree; DeSanto, Kristen; O'Brien, Nancy; Purdon, Michelle; Delgado, Diana

2016-09-01

The purpose of this review is to evaluate the tools used to measure the financial value of libraries in a clinical setting. Searches were carried out on ten databases for the years 2003-2013, with a final search before completion to identify any recent papers. Eleven papers met the final inclusion criteria. There was no evidence of a single 'best practice', and many metrics used to measure financial impact of clinical libraries were developed on an ad hoc basis locally. The most common measures of financial impact were value of time saved, value of resource collection against cost of alternative sources, cost avoidance and revenue generated through assistance on grant submissions. Few papers provided an insight into the longer term impact on the library service resulting from submitting return on investment (ROI) or other financial impact statements. There are limited examples of metrics which clinical libraries can use to measure explicit financial impact. The methods highlighted in this literature review are generally implicit in the measures used and lack robustness. There is a need for future research to develop standardised, validated tools that clinical libraries can use to demonstrate their financial impact. © 2016 Health Libraries Group.
Ghana Library Journal: Advanced Search

African Journals Online (AJOL)

Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...
A Study on Librarian Service Providers' Awareness and Perceptions of Library Services for the Disabled

Directory of Open Access Journals (Sweden)

Younghee Noh

2011-12-01

Full Text Available The purpose of this study is to improve library promotional marketing for the disabled by identifying requirements of public library disability services. This study aimed to investigate librarian service providers' awareness of library programs for the disabled in order to prepare a systematic plan for promoting such library services. Research methods used are a literature analysis and survey. First, the ratio of respondents with experience promoting activities and services for the disabled was less than 50%. Second, regarding methods for promoting library disability services, the respondents used library homepages, press releases, library user guides, library newsletters, and library pamphlets in that order. Third, when asked what kind of PR media the library disability service providers had experience with and how often they use it, library boards and banners were the most common response. Fourth, suggested improvements to the current design and content of PR materials included: clearer word choice (or greater understandability, more detailed descriptions, simpler layouts, and more interesting or eye-catching content in that order. Fifth, the library disability services which are in the most need of public relations were guide information for library disability services, Library and Information Service (DOI services and search services, using alternative materials and the library collection, and aiding the information search. Overall, when evaluating the promotion of disability services in Korea, the library's public relations for disabled services needs to improve because currently neither librarians nor the disabled community they are targeting has frequent or quality experience with it. Thus, the policy department for the library disability services must develop a variety of promotional strategies adjusted for each type of the disability and distribute PR materials to service providers individually, making sure to utilize effective PR
Studying the Night Shift: A Multi-method Analysis of Overnight Academic Library Users

Directory of Open Access Journals (Sweden)

David Schwieder

2017-09-01

Full Text Available Abstract Objective – This paper reports on a study which assessed the preferences and behaviors of overnight library users at a major state university. The findings were used to guide the design and improvement of overnight library resources and services, and the selection of a future overnight library site. Methods – A multi-method design used descriptive and correlational statistics to analyze data produced by a multi-sample survey of overnight library users. These statistical methods included rankings, percentages, and multiple regression. Results – Results showed a strong consistency across statistical methods and samples. Overnight library users consistently prioritized facilities like power outlets for electronic devices, and group and quiet study spaces, and placed far less emphasis on assistance from library staff. Conclusions – By employing more advanced statistical and sampling procedures than had been found in previous research, this paper strengthens the validity of findings on overnight user preferences and behaviors. The multi-method research design can also serve to guide future work in this area.
Is There a Standard Default Keyword Operator? A Bibliometric Analysis of Processing Options Chosen by Libraries To Execute Keyword Searches in Online Public Access Catalogs.

Science.gov (United States)

Klein, Gary M.

1994-01-01

Online public access catalogs from 67 libraries using NOTIS software were searched using Internet connections to determine the positional operators selected as the default keyword operator on each catalog. Results indicate the lack of a processing standard for keyword searches. Five tables provide information. (Author/AEF)
Employed and unemployed job search methods: Australian evidence on search duration, wages and job stability

OpenAIRE

Colin Green

2012-01-01

This paper examines the use and impact of job search methods of both unemployed and employed job seekers. Informal job search methods are associated with relativel high level of job exit and shorter search duration. Job exists through the public employment agency (PEA) display positive duration dependence for the unemployed. This may suggest that the PEA is used as a job search method of last resort. Informal job search methods have lower associated duration in search and higher wages than th...
Modern Library Facilities to Enhance Learning in a Teachers' College

African Journals Online (AJOL)

unique firstlady

Modern facilities/Equipments in the library that can aid effective utilization of ... we acquire the education by imitation or learning through the process of “doing it .... spent while searching for materials compared to traditional services method.
Comparison tomography relocation hypocenter grid search and guided grid search method in Java island

International Nuclear Information System (INIS)

Nurdian, S. W.; Adu, N.; Palupi, I. R.; Raharjo, W.

2016-01-01

The main data in this research is earthquake data recorded from 1952 to 2012 with 9162 P wave and 2426 events are recorded by 30 stations located around Java island. Relocation hypocenter processed using grid search and guidded grid search method. Then the result of relocation hypocenter become input for tomography pseudo bending inversion process. It can be used to identification the velocity distribution in subsurface. The result of relocation hypocenter by grid search and guided grid search method after tomography process shown in locally and globally. In locally area grid search method result is better than guided grid search according to geological reseach area. But in globally area the result of guided grid search method is better for a broad area because the velocity variation is more diverse than the other one and in accordance with local geological research conditions. (paper)
Library resources on the Internet

Science.gov (United States)

Buchanan, Nancy L.

1995-07-01

Library resources are prevalent on the Internet. Library catalogs, electronic books, electronic periodicals, periodical indexes, reference sources, and U.S. Government documents are available by telnet, Gopher, World Wide Web, and FTP. Comparatively few copyrighted library resources are available freely on the Internet. Internet implementations of library resources can add useful features, such as full-text searching. There are discussion lists, Gophers, and World Wide Web pages to help users keep up with new resources and changes to existing ones. The future will bring more library resources, more types of library resources, and more integrated implementations of such resources to the Internet.
Bibliometrics and academic staff assessment in Polish university libraries - current trends

Directory of Open Access Journals (Sweden)

Danuta Ryś

2016-12-01

Full Text Available Academic staff assessment in Poland is, to a large extent, based on bibliographic indicators, such as the number of scientific publications produced, the Ministry of Science and Higher Education score pertaining to the journal rank and the publication type, as well as the number of citations and derivatives. Relevant data is retrieved from bibliographic databases developed by libraries, international citation indexes available for Polish scientific institutions under a national licence, and from open-access international and Polish sources, which are briefly presented in the article. The workload entailed, and in consequence, the results of this citation search vary depending on the search method applied. For this reason university staff members and university authorities often seek assistance for this from the university library staff. This in return provides an opportunity for libraries to increase their role within the academic community.In order to investigate the matter further, the authors conducted a survey among the largest academic libraries in Poland. The findings confirm that bibliometric processes (namely, the registration and the formal acceptance of university staff scientific publications, and compilation of citation reports have become a vital part of modern library work. Bibliographies of university staff publications developed by libraries include various bibliometric indicators (those most frequently used being identified in the article, and have become an important source of statistical and bibliometric information. The survey results highlight the most frequently used bibliometric sources and methods. Examples of bibliographic databases created by the libraries and bibliometric indicators used within these databases are also presented.
Methods of Usability Testing in Libraries Web Sites

Directory of Open Access Journals (Sweden)

Eman Fawzy

2006-03-01

Full Text Available A Study about libraries' web sites evaluation, that is the Usability, the study talking about methods of usability testing and define it, and its important in web sites evaluation, then details the methods of usability: questionnaire, core groups, testing experimental model, cards arrangement, and composed evaluation.
Academic Medical Library Services Contribute to Scholarship in Medical Faculty and Residents

Directory of Open Access Journals (Sweden)

Peace Ossom Williamson

2017-09-01

Full Text Available A Review of: Quesenberry, A. C., Oelschlegel, S., Earl, M., Leonard, K., & Vaughn, C. J. (2016. The impact of library resources and services on the scholarly activity of medical faculty and residents. Medical Reference Services Quarterly, 35(3, 259-265. http://dx.doi.org/10.1080/02763869.2016.1189778 Abstract Objective – To assess the impact of academic medical library services and resources on information-seeking behaviours during the academic efforts of medical faculty and residents. Design – Value study derived from a 23-item survey. Setting – Public medical residency program and training hospital in Tennessee, USA. Subjects – 433 faculty and residents currently employed by or completing residency in an academic medical centre. Methods – Respondents completed a 23-question survey about their use of library resources and services in preparation for publishing, presenting, and teaching. The library services in the survey included literature searches completed by librarians and document delivery for preparation of publications, presentations, and lecture material. The survey also included questions about how resources were being accessed in preparation for scholarship. The survey sought information on whether respondents published articles or chapters or presented papers or posters in the previous three years. If respondents answered in the affirmative to one of the aforementioned methods of scholarship, they were provided with further questions about how they access library resources and whether they sought mediated literature search and document delivery services in preparation for their recent presentations and publications. The survey also included questions concerning what types of scholarly activity prompt faculty and residents to use online library resources. Main Results – The study was provided to 433 subjects, including 220 faculty and 213 residents, contacted through an email distribution list. The response rate to the
Improvement Of Search Process In Electronic Catalogues

Directory of Open Access Journals (Sweden)

Titas Savickas

2014-05-01

Full Text Available The paper presents investigation on search in electronic catalogues. The chosen problem domain is the search system in the electronic catalogue of Lithuanian Academic Libraries. The catalogue uses ALEPH system with MARC21 bibliographic format. The article presents analysis of problems pertaining to the current search engine and user expectations related to the search system of the electronic catalogue of academic libraries. Subsequent to analysis, the research paper presents the architecture for a semantic search system in the electronic catalogue that uses search process designed to improve search results for users.
Automated recycling of chemistry for virtual screening and library design.

Science.gov (United States)

Vainio, Mikko J; Kogej, Thierry; Raubacher, Florian

2012-07-23

An early stage drug discovery project needs to identify a number of chemically diverse and attractive compounds. These hit compounds are typically found through high-throughput screening campaigns. The diversity of the chemical libraries used in screening is therefore important. In this study, we describe a virtual high-throughput screening system called Virtual Library. The system automatically "recycles" validated synthetic protocols and available starting materials to generate a large number of virtual compound libraries, and allows for fast searches in the generated libraries using a 2D fingerprint based screening method. Virtual Library links the returned virtual hit compounds back to experimental protocols to quickly assess the synthetic accessibility of the hits. The system can be used as an idea generator for library design to enrich the screening collection and to explore the structure-activity landscape around a specific active compound.
About Libraries - AcEST | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...ormat text file. Data file File name: acest_library.zip File URL: ftp://ftp.biosciencedbc.jp/archive/acest/L...ATEST/acest_library.zip File size: 2KB Simple search URL http://togodb.biosciencedbc.jp/togodb/view/archiv...s Database Database Description Download License Update History of This Database Site Policy | Contact Us About Libraries - AcEST | LSDB Archive ...
Usability Testing as a Method to Refine a Health Sciences Library Website.

Science.gov (United States)

Denton, Andrea H; Moody, David A; Bennett, Jason C

2016-01-01

User testing, a method of assessing website usability, can be a cost-effective and easily administered process to collect information about a website's effectiveness. A user experience (UX) team at an academic health sciences library has employed user testing for over three years to help refine the library's home page. Test methodology used in-person testers using the "think aloud" method to complete tasks on the home page. Review of test results revealed problem areas of the design and redesign; further testing was effective in refining the page. User testing has proved to be a valuable method to engage users and provide feedback to continually improve the library's home page.
Heuristic method for searching global maximum of multimodal unknown function

Energy Technology Data Exchange (ETDEWEB)

Kamei, K; Araki, Y; Inoue, K

1983-06-01

The method is composed of three kinds of searches. They are called g (grasping)-mode search, f (finding)-mode search and c (confirming)-mode search. In the g-mode search and the c-mode search, a heuristic method is used which was extracted from search behaviors of human subjects. In f-mode search, the simplex method is used which is well known as a search method for unimodal unknown function. Each mode search and its transitions are shown in the form of flowchart. The numerical results for one-dimensional through six-dimensional multimodal functions prove the proposed search method to be an effective one. 11 references.
Collection evaluation in University libraries (II. Methods based on collection use

Directory of Open Access Journals (Sweden)

Àngels Massísimo i Sánchez de Boado

2004-01-01

Full Text Available This is our second paper devoted to the collection evaluation in the university libraries. Seven methods are described, based on collection use. Their advantages and disadvantages are discussed, as well as their usefulness for a range of library types
Phonetic search methods for large speech databases

CERN Document Server

Moyal, Ami; Tetariy, Ella; Gishri, Michal

2013-01-01

“Phonetic Search Methods for Large Databases” focuses on Keyword Spotting (KWS) within large speech databases. The brief will begin by outlining the challenges associated with Keyword Spotting within large speech databases using dynamic keyword vocabularies. It will then continue by highlighting the various market segments in need of KWS solutions, as well as, the specific requirements of each market segment. The work also includes a detailed description of the complexity of the task and the different methods that are used, including the advantages and disadvantages of each method and an in-depth comparison. The main focus will be on the Phonetic Search method and its efficient implementation. This will include a literature review of the various methods used for the efficient implementation of Phonetic Search Keyword Spotting, with an emphasis on the authors’ own research which entails a comparative analysis of the Phonetic Search method which includes algorithmic details. This brief is useful for resea...
How to Use the Marine Realms Information Bank (MRIB) Digital Libraries

Science.gov (United States)

Lightsom, Frances L.; Allwardt, Alan O.

2009-01-01

Marine Realms Information Bank (MRIB) digital libraries provide access to free online scientific resources about oceans, coasts, and coastal watersheds. MRIB allows category, geographic, and keyword searching, alone or in combination. Instructions for searching the three MRIB libraries and for refining the searches are explained in detail.

Processing methods for temperature-dependent MCNP libraries

International Nuclear Information System (INIS)

Li Songyang; Wang Kan; Yu Ganglin

2008-01-01

In this paper,the processing method of NJOY which transfers ENDF files to ACE (A Compact ENDF) files (point-wise cross-Section file used for MCNP program) is discussed. Temperatures that cover the range for reactor design and operation are considered. Three benchmarks are used for testing the method: Jezebel Benchmark, 28 cm-thick Slab Core Benchmark and LWR Benchmark with Burnable Absorbers. The calculation results showed the precision of the neutron cross-section library and verified the correct processing methods in usage of NJOY. (authors)
MyLibrary: A Web Personalized Digital Library.

Science.gov (United States)

Rocha, Catarina; Xexeo, Geraldo; da Rocha, Ana Regina C.

With the increasing availability of information on Internet information providers, like search engines, digital libraries and online databases, it becomes more important to have personalized systems that help users to find relevant information. One type of personalization that is growing in use is recommender systems. This paper presents…
Hyperopt: a Python library for model selection and hyperparameter optimization

Science.gov (United States)

Bergstra, James; Komer, Brent; Eliasmith, Chris; Yamins, Dan; Cox, David D.

2015-01-01

Sequential model-based optimization (also known as Bayesian optimization) is one of the most efficient methods (per function evaluation) of function minimization. This efficiency makes it appropriate for optimizing the hyperparameters of machine learning algorithms that are slow to train. The Hyperopt library provides algorithms and parallelization infrastructure for performing hyperparameter optimization (model selection) in Python. This paper presents an introductory tutorial on the usage of the Hyperopt library, including the description of search spaces, minimization (in serial and parallel), and the analysis of the results collected in the course of minimization. This paper also gives an overview of Hyperopt-Sklearn, a software project that provides automatic algorithm configuration of the Scikit-learn machine learning library. Following Auto-Weka, we take the view that the choice of classifier and even the choice of preprocessing module can be taken together to represent a single large hyperparameter optimization problem. We use Hyperopt to define a search space that encompasses many standard components (e.g. SVM, RF, KNN, PCA, TFIDF) and common patterns of composing them together. We demonstrate, using search algorithms in Hyperopt and standard benchmarking data sets (MNIST, 20-newsgroups, convex shapes), that searching this space is practical and effective. In particular, we improve on best-known scores for the model space for both MNIST and convex shapes. The paper closes with some discussion of ongoing and future work.
A rapid method for screening arrayed plasmid cDNA library by PCR

International Nuclear Information System (INIS)

Hu Yingchun; Zhang Kaitai; Wu Dechang; Li Gang; Xiang Xiaoqiong

1999-01-01

Objective: To develop a PCR-based method for rapid and effective screening of arrayed plasmid cDNA library. Methods: The plasmid cDNA library was arrayed and screened by PCR with a particular set of primers. Results: Four positive clones were obtained through about one week. Conclusion: This method can be applied to screening not only normal cDNA clones, but also cDNA clones-containing small size fragments. This method offers significant advantages over traditional screening method in terms of sensitivity, specificity and efficiency
An automated full-symmetry Patterson search method

International Nuclear Information System (INIS)

Rius, J.; Miravitlles, C.

1987-01-01

A full-symmetry Patterson search method is presented that performs a molecular coarse rotation search in vector space and orientation refinement using the σ function. The oriented molecule is positioned using the fast translation function τ 0 , which is based on the automated interpretation of τ projections using the sum function. This strategy reduces the number of Patterson-function values to be stored in the rotation search, and the use of the τ 0 function minimizes the required time for the development of all probable rotation search solutions. The application of this method to five representative test examples is shown. (orig.)
The Role of School Libraries | Wali | Nigerian School Library Journal

African Journals Online (AJOL)

Nigerian School Library Journal. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 1 (2002) >. Log in or Register to get access to full text downloads.
Case study: the Health SmartLibrary* experiences in web personalization and customization at the Galter Health Sciences Library, Northwestern University

Science.gov (United States)

Shedlock, James; Frisque, Michelle; Hunt, Steve; Walton, Linda; Handler, Jonathan; Gillam, Michael

2010-01-01

Question: How can the user's access to health information, especially full-text articles, be improved? The solution is building and evaluating the Health SmartLibrary (HSL). Setting: The setting is the Galter Health Sciences Library, Feinberg School of Medicine, Northwestern University. Method: The HSL was built on web-based personalization and customization tools: My E-Resources, Stay Current, Quick Search, and File Cabinet. Personalization and customization data were tracked to show user activity with these value-added, online services. Main Results: Registration data indicated that users were receptive to personalized resource selection and that the automated application of specialty-based, personalized HSLs was more frequently adopted than manual customization by users. Those who did customize customized My E-Resources and Stay Current more often than Quick Search and File Cabinet. Most of those who customized did so only once. Conclusion: Users did not always take advantage of the services designed to aid their library research experiences. When personalization is available at registration, users readily accepted it. Customization tools were used less frequently; however, more research is needed to determine why this was the case. PMID:20428276
Analysis of a librarian-mediated literature search service.

Science.gov (United States)

Friesen, Carol; Lê, Mê-Linh; Cooke, Carol; Raynard, Melissa

2015-01-01

Librarian-mediated literature searching is a key service provided at medical libraries. This analysis outlines ten years of data on 19,248 literature searches and describes information on the volume and frequency of search requests, time spent per search, databases used, and professional designations of the patron requestors. Combined with information on best practices for expert searching and evaluations of similar services, these findings were used to form recommendations on the improvement and standardization of a literature search service at a large health library system.
Undergraduates Prefer Federated Searching to Searching Databases Individually. A Review of: Belliston, C. Jeffrey, Jared L. Howland, & Brian C. Roberts. “Undergraduate Use of Federated Searching: A Survey of Preferences and Perceptions of Value-Added Functionality.” College & Research Libraries 68.6 (Nov. 2007: 472-86.

Directory of Open Access Journals (Sweden)

Genevieve Gore

2008-09-01

Full Text Available Objective – To determine whether use offederated searching by undergraduates saves time, meets their information needs, is preferred over searching databases individually, and provides results of higher quality. Design – Crossover study.Setting – Three American universities, all members of the Consortium of Church Libraries & Archives (CCLA: BYU (Brigham Young University, a large research university; BYUH (Brigham Young University – Hawaii, a small baccalaureate college; and BYUI (Brigham Young University – Idaho, a large baccalaureate collegeSubjects – Ninety-five participants recruited via e-mail invitations sent to a random sample of currently enrolled undergraduates at BYU, BYUH, and BYUI.Methods – Participants were given written directions to complete a literature search for journal articles on two biology-related topics using two search methods: 1. federated searching with WebFeat® (implemented in the same way for this study at the three universities and 2. a hyperlinked list of databases to search individually. Both methods used the same set of seven databases. Each topic was assigned in random order to one of the two search methods, also assigned in random order, for a total of two searches per participant. The time to complete the searches was recorded. Students compiled their list of citations, which were later normalized and graded. To analyze the quality of the citations, one quantitative rubric was created by librarians and one qualitative rubric was approved by a faculty member at BYU. The librarian-created rubric included the journal impact factor (from ISI’s Journal Citation Reports®, the proportion of citations from peer-reviewed journals (determined from Ulrichsweb.com™ to total citations, and the timeliness of the articles. The faculty-approved rubric included three criteria: relevance to the topic, quality of the individual citations (good quality: primary research results, peer-reviewed sources, and
Digital Libraries--Methods and Applications

Science.gov (United States)

Huang, Kuo Hung, Ed.

2011-01-01

Digital library is commonly seen as a type of information retrieval system which stores and accesses digital content remotely via computer networks. However, the vision of digital libraries is not limited to technology or management, but user experience. This book is an attempt to share the practical experiences of solutions to the operation of…
Privacy and User Experience in 21st Century Library Discovery

Directory of Open Access Journals (Sweden)

Shayna Pekala

2017-06-01

Full Text Available Over the last decade, libraries have taken advantage of emerging technologies to provide new discovery tools to help users find information and resources more efficiently. In the wake of this technological shift in discovery, privacy has become an increasingly prominent and complex issue for libraries. The nature of the web, over which users interact with discovery tools, has substantially diminished the library’s ability to control patron privacy. The emergence of a data economy has led to a new wave of online tracking and surveillance, in which multiple third parties collect and share user data during the discovery process, making it much more difficult, if not impossible, for libraries to protect patron privacy. In addition, users are increasingly starting their searches with web search engines, diminishing the library’s control over privacy even further. While libraries have a legal and ethical responsibility to protect patron privacy, they are simultaneously challenged to meet evolving user needs for discovery. In a world where “search” is synonymous with Google, users increasingly expect their library discovery experience to mimic their experience using web search engines. However, web search engines rely on a drastically different set of privacy standards, as they strive to create tailored, personalized search results based on user data. Libraries are seemingly forced to make a choice between delivering the discovery experience users expect and protecting user privacy. This paper explores the competing interests of privacy and user experience, and proposes possible strategies to address them in the future design of library discovery tools.
Detecting atypical examples of known domain types by sequence similarity searching: the SBASE domain library approach.

Science.gov (United States)

Dhir, Somdutta; Pacurar, Mircea; Franklin, Dino; Gáspári, Zoltán; Kertész-Farkas, Attila; Kocsor, András; Eisenhaber, Frank; Pongor, Sándor

2010-11-01

SBASE is a project initiated to detect known domain types and predicting domain architectures using sequence similarity searching (Simon et al., Protein Seq Data Anal, 5: 39-42, 1992, Pongor et al, Nucl. Acids. Res. 21:3111-3115, 1992). The current approach uses a curated collection of domain sequences - the SBASE domain library - and standard similarity search algorithms, followed by postprocessing which is based on a simple statistics of the domain similarity network (http://hydra.icgeb.trieste.it/sbase/). It is especially useful in detecting rare, atypical examples of known domain types which are sometimes missed even by more sophisticated methodologies. This approach does not require multiple alignment or machine learning techniques, and can be a useful complement to other domain detection methodologies. This article gives an overview of the project history as well as of the concepts and principles developed within this the project.
Multilevel library instruction for emerging nursing roles.

Science.gov (United States)

Francis, B W; Fisher, C C

1995-10-01

As new nursing roles emerge that involve greater decision making than in the past, added responsibility for outcomes and cost control, and increased emphasis on primary care, the information-seeking skills needed by nurses change. A search of library and nursing literature indicates that there is little comprehensive library instruction covering all levels of nursing programs: undergraduate, returning registered nurses, and graduate students. The University of Florida is one of the few places that has such a multilevel, course-integrated curriculum in place for all entrants into the nursing program. Objectives have been developed for each stage of learning. The courses include instruction in the use of the online public access catalog, printed resources, and electronic databases. A library classroom equipped with the latest technology enables student interaction with electronic databases. This paper discusses the program and several methods used to evaluate it.
Outsourcing in libraries

Directory of Open Access Journals (Sweden)

Matjaž Žaucer

1999-01-01

Full Text Available Like other organisations more flexible libraries tend to conform to the changing environment as this is the only way to be successful and effective. They are expected to offer "more for less" and they are reorganising and searching the ways to reduce the costs. Outsourcing is one of possible solutions. The article deals with the possibilities of outsourcing in libraries, higher quality of their work eoneentrated on principal activities and gives some experienees in this field.
Helping Students Use Virtual Libraries Effectively.

Science.gov (United States)

Fitzgerald, Mary Ann; Galloway, Chad

2001-01-01

Describes a study in which online behavior of high school and undergraduate students using GALILEO (Georgia Library Learning Online), a virtual library, were observed. Topics include cognitive demands; technology literacy; domain knowledge; search strategies; relevance; evaluation of information; information literacy standards; and suggestions to…
Public libraries, as an infrastructure for a sustainable public sphere: A systematic review of research: A preliminary paper

DEFF Research Database (Denmark)

Audunson, Ragnar; Svandhild, Aabø,; Blomgren, Roger

of the major findings are: Research on libraries as public sphere institutions cover a wide range of topics the dominating being freedom of access to information, often related to social inclusion, empowerment and justice. Contributions are often normative and non-empirical, but the proportion of empirically...... based research is increasing. This paper focuses on contributions related to public libraries.......This paper is based on a systematic literature search aiming at identifying research on the role of libraries as institutions underpinning a sustainable public sphere in a digital age. The major research questions are: 1. Is systematic literature search a fruitful method when it comes to a social...
Collection Metadata Solutions for Digital Library Applications

Science.gov (United States)

Hill, Linda L.; Janee, Greg; Dolin, Ron; Frew, James; Larsgaard, Mary

1999-01-01

Within a digital library, collections may range from an ad hoc set of objects that serve a temporary purpose to established library collections intended to persist through time. The objects in these collections vary widely, from library and data center holdings to pointers to real-world objects, such as geographic places, and the various metadata schemas that describe them. The key to integrated use of such a variety of collections in a digital library is collection metadata that represents the inherent and contextual characteristics of a collection. The Alexandria Digital Library (ADL) Project has designed and implemented collection metadata for several purposes: in XML form, the collection metadata "registers" the collection with the user interface client; in HTML form, it is used for user documentation; eventually, it will be used to describe the collection to network search agents; and it is used for internal collection management, including mapping the object metadata attributes to the common search parameters of the system.
Building Earth's Largest Library: Driving into the Future.

Science.gov (United States)

Coffman, Steve

1999-01-01

Examines the Amazon.com online bookstore as a blueprint for designing the world's largest library. Topics include selection; accessibility and convenience; quality of Web sites and search tools; personalized service; library collection development, including interlibrary loan; library catalogs and catalog records; a circulation system; costs;…
Comprehensive evaluation and optimization of amplicon library preparation methods for high-throughput antibody sequencing.

Science.gov (United States)

Menzel, Ulrike; Greiff, Victor; Khan, Tarik A; Haessler, Ulrike; Hellmann, Ina; Friedensohn, Simon; Cook, Skylar C; Pogson, Mark; Reddy, Sai T

2014-01-01

High-throughput sequencing (HTS) of antibody repertoire libraries has become a powerful tool in the field of systems immunology. However, numerous sources of bias in HTS workflows may affect the obtained antibody repertoire data. A crucial step in antibody library preparation is the addition of short platform-specific nucleotide adapter sequences. As of yet, the impact of the method of adapter addition on experimental library preparation and the resulting antibody repertoire HTS datasets has not been thoroughly investigated. Therefore, we compared three standard library preparation methods by performing Illumina HTS on antibody variable heavy genes from murine antibody-secreting cells. Clonal overlap and rank statistics demonstrated that the investigated methods produced equivalent HTS datasets. PCR-based methods were experimentally superior to ligation with respect to speed, efficiency, and practicality. Finally, using a two-step PCR based method we established a protocol for antibody repertoire library generation, beginning from inputs as low as 1 ng of total RNA. In summary, this study represents a major advance towards a standardized experimental framework for antibody HTS, thus opening up the potential for systems-based, cross-experiment meta-analyses of antibody repertoires.
Evaluation of academic library collection using a check-list method

Directory of Open Access Journals (Sweden)

Kornelija Petr Balog

2015-04-01

Full Text Available The purpose of this paper is to evaluate the quality of the ILS library collection of the Faculty of Humanities and Social Sciences (FHSS in Osijek, Croatia and its congruence with the curriculum. The quality of the collection is measured using the check-list method. The required and optional reading lists of the Department of Information Sciences at the FHSS (academic year 2011/2012 are used as standard lists that the library holdings are compared to. The results found that the library does not have 30.8 per cent of the titles on the reading lists. The remaining 33.9 per cent of the titles are accessible in the library, 28.5 per cent are free electronic resources, and 6.8 per cent of titles are accessible for students through the Department’s Moodle, Learning Management System. The study provides data about the titles available and not available in the FHSS library. However, it does not differentiate between the titles on the required and optional reading lists. This study provides the FHSS librarians with the list of titles that should be obtained in the near future. In Croatia, very few papers on collection assessment have been published so far, and this is the first study about the quality of a library collection at the University of Osijek. The paper attempts to fill that gap and contribute to a deeper understanding of the quality of library collections in the Croatian academic setting.

An improved yeast transformation method for the generation of very large human antibody libraries.

Science.gov (United States)

Benatuil, Lorenzo; Perez, Jennifer M; Belk, Jonathan; Hsieh, Chung-Ming

2010-04-01

Antibody library selection by yeast display technology is an efficient and highly sensitive method to identify binders to target antigens. This powerful selection tool, however, is often hampered by the typically modest size of yeast libraries (approximately 10(7)) due to the limited yeast transformation efficiency, and the full potential of the yeast display technology for antibody discovery and engineering can only be realized if it can be coupled with a mean to generate very large yeast libraries. We describe here a yeast transformation method by electroporation that allows for the efficient generation of large antibody libraries up to 10(10) in size. Multiple components and conditions including CaCl(2), MgCl(2), sucrose, sorbitol, lithium acetate, dithiothreitol, electroporation voltage, DNA input and cell volume have been tested to identify the best combination. By applying this developed protocol, we have constructed a 1.4 x 10(10) human spleen antibody library essentially in 1 day with a transformation efficiency of 1-1.5 x 10(8) transformants/microg vector DNA. Taken together, we have developed a highly efficient yeast transformation method that enables the generation of very large and productive human antibody libraries for antibody discovery, and we are now routinely making 10(9) libraries in a day for antibody engineering purposes.
A borderless Library

CERN Multimedia

CERN Library

2010-01-01

The CERN Library has a large collection of documents in online or printed format in all disciplines needed by physicists, engineers and technicians. However, users sometimes need to read documents not available at CERN. But don’t worry! Thanks to its Interlibrary loan and document delivery service, the CERN Library can still help you. Just fill in the online form or email us. We will then locate the document in other institutions and order it for you free of charge. The CERN Library cooperates with the largest libraries in Europe, such as ETH (Eidgenössische Technische Hochschule) in Zurich, TIB (Technische Informationsbibliothek) in Hanover and the British Library in London. Thanks to our network and our expertise in document search, most requests are satisfied in record time: articles are usually served in .pdf version a few hours after the order, and books or other printed materials are delivered within a few days. It is possible to ask for all types of documents suc...
Building a Library App Portfolio with Redis and Django

Directory of Open Access Journals (Sweden)

Jeremy Nelson

2013-01-01

Full Text Available The Tutt Library at Colorado College is developing a portfolio of library applications for use by patrons and library staff. Developed under an iterative and incremental agile model, these single-use HTML5 applications target multiple devices while using Bootstrap and Django to deliver fast and responsive interfaces to underlying FRBR datastores running on Redis, an advanced NoSQL database server. Two types are delineated: applications for access and discovery, which are available to everyone; and productivity applications, which are primarily for library staff to administer and manage the FRBR-RDA records. The access portfolio includes Book Search, Article Search, Call Number, and Library Hours applications. The productivity side includes an Orders App and a MARC Batch application for ingesting MARC records as FRBR entities using RDA Core attributes. When a critical threshold is reached, the Tutt Library intends to replace its legacy ILS with this library application portfolio.
A library based fitting method for visual reflectance spectroscopy of human skin

International Nuclear Information System (INIS)

Verkruysse, Wim; Zhang Rong; Choi, Bernard; Lucassen, Gerald; Svaasand, Lars O; Nelson, J Stuart

2005-01-01

The diffuse reflectance spectrum of human skin in the visible region (400-800 nm) contains information on the concentrations of chromophores such as melanin and haemoglobin. This information may be extracted by fitting the reflectance spectrum with an optical diffusion based analytical expression applied to a layered skin model. With the use of the analytical expression, it is assumed that light transport is dominated by scattering. For port wine stain (PWS) and highly pigmented human skin, however, this assumption may not be valid resulting in a potentially large error in visual reflectance spectroscopy (VRS). Monte Carlo based techniques can overcome this problem but are currently too computationally intensive to be combined with previously used fitting procedures. The fitting procedure presented herein is based on a library search which enables the use of accurate reflectance spectra based on forward Monte Carlo simulations or diffusion theory. This allows for accurate VRS to characterize chromophore concentrations in PWS and highly pigmented human skin. The method is demonstrated using both simulated and measured reflectance spectra. An additional advantage of the method is that the fitting procedure is very fast
A library based fitting method for visual reflectance spectroscopy of human skin

Energy Technology Data Exchange (ETDEWEB)

Verkruysse, Wim [Beckman Laser Institute, University of California, Irvine, CA 92612 (United States); Zhang Rong [Beckman Laser Institute, University of California, Irvine, CA 92612 (United States); Choi, Bernard [Beckman Laser Institute, University of California, Irvine, CA 92612 (United States); Lucassen, Gerald [Personal Care Institute, Philips Research, Prof Holstlaan 4, Eindhoven (Netherlands); Svaasand, Lars O [Department of Physical Electronics Norwegian University of Science and Technology, N-7491 Trondheim (Norway); Nelson, J Stuart [Beckman Laser Institute, University of California, Irvine, CA 92612 (United States)

2005-01-07

The diffuse reflectance spectrum of human skin in the visible region (400-800 nm) contains information on the concentrations of chromophores such as melanin and haemoglobin. This information may be extracted by fitting the reflectance spectrum with an optical diffusion based analytical expression applied to a layered skin model. With the use of the analytical expression, it is assumed that light transport is dominated by scattering. For port wine stain (PWS) and highly pigmented human skin, however, this assumption may not be valid resulting in a potentially large error in visual reflectance spectroscopy (VRS). Monte Carlo based techniques can overcome this problem but are currently too computationally intensive to be combined with previously used fitting procedures. The fitting procedure presented herein is based on a library search which enables the use of accurate reflectance spectra based on forward Monte Carlo simulations or diffusion theory. This allows for accurate VRS to characterize chromophore concentrations in PWS and highly pigmented human skin. The method is demonstrated using both simulated and measured reflectance spectra. An additional advantage of the method is that the fitting procedure is very fast.
A library based fitting method for visual reflectance spectroscopy of human skin

Science.gov (United States)

Verkruysse, Wim; Zhang, Rong; Choi, Bernard; Lucassen, Gerald; Svaasand, Lars O.; Nelson, J. Stuart

2005-01-01

The diffuse reflectance spectrum of human skin in the visible region (400-800 nm) contains information on the concentrations of chromophores such as melanin and haemoglobin. This information may be extracted by fitting the reflectance spectrum with an optical diffusion based analytical expression applied to a layered skin model. With the use of the analytical expression, it is assumed that light transport is dominated by scattering. For port wine stain (PWS) and highly pigmented human skin, however, this assumption may not be valid resulting in a potentially large error in visual reflectance spectroscopy (VRS). Monte Carlo based techniques can overcome this problem but are currently too computationally intensive to be combined with previously used fitting procedures. The fitting procedure presented herein is based on a library search which enables the use of accurate reflectance spectra based on forward Monte Carlo simulations or diffusion theory. This allows for accurate VRS to characterize chromophore concentrations in PWS and highly pigmented human skin. The method is demonstrated using both simulated and measured reflectance spectra. An additional advantage of the method is that the fitting procedure is very fast.
An introduction to harmony search optimization method

CERN Document Server

Wang, Xiaolei; Zenger, Kai

2014-01-01

This brief provides a detailed introduction, discussion and bibliographic review of the nature1-inspired optimization algorithm called Harmony Search. It uses a large number of simulation results to demonstrate the advantages of Harmony Search and its variants and also their drawbacks. The authors show how weaknesses can be amended by hybridization with other optimization methods. The Harmony Search Method with Applications will be of value to researchers in computational intelligence in demonstrating the state of the art of research on an algorithm of current interest. It also helps researche
Activity-Based Costing (ABC and Time-Driven Activity-Based Costing (TDABC: Applicable Methods for University Libraries?

Directory of Open Access Journals (Sweden)

Kate-Riin Kont

2011-01-01

Full Text Available Objective – This article provides an overview of how university libraries research and adapt new cost accounting models, such as “activity-based costing” (ABC and “time-driven activity-based costing” (TDABC, focusing on the strengths and weaknesses of both methods to determine which of these two is suitable for application in university libraries.Methods – This paper reviews and summarizes the literature on cost accounting and costing practices of university libraries. A brief overview of the history of cost accounting, costing, and time and motion studies in libraries is also provided. The ABC and the TDABC method, designed as a revised and easier version of the ABC by Kaplan and Anderson (Kaplan & Anderson 2004 at the beginning of the 21st century, as well as the adoption and adaptation of these methods by university libraries are described, and their strengths and weaknesses, as well as their suitability for university libraries, are analyzed. Results – Cost accounting and costing studies in libraries have a long history, the first of these dating back to 1877. The development of cost accounting and time and motion studies can be seen as a natural evolution of techniques which were created to solve management problems. The ABC method is the best-known management accounting innovation of the last 20 years, and is already widely used in university libraries around the world. However, setting up an ABC system can be very costly, and the system needs to be regularly updated, which further increases its costs. The TDABC system can not only be implemented more quickly (and thus more cheaply, but also can be updated more easily than the traditional ABC, which makes the TDABC the more suitable method for university libraries.Conclusion – Both methods are suitable for university libraries. However, the ABC method can only be implemented in collaboration with an accounting department. The TDABC method can be tested and implemented by
Critical Features of Fragment Libraries for Protein Structure Prediction.

Science.gov (United States)

Trevizani, Raphael; Custódio, Fábio Lima; Dos Santos, Karina Baptista; Dardenne, Laurent Emmanuel

2017-01-01

The use of fragment libraries is a popular approach among protein structure prediction methods and has proven to substantially improve the quality of predicted structures. However, some vital aspects of a fragment library that influence the accuracy of modeling a native structure remain to be determined. This study investigates some of these features. Particularly, we analyze the effect of using secondary structure prediction guiding fragments selection, different fragments sizes and the effect of structural clustering of fragments within libraries. To have a clearer view of how these factors affect protein structure prediction, we isolated the process of model building by fragment assembly from some common limitations associated with prediction methods, e.g., imprecise energy functions and optimization algorithms, by employing an exact structure-based objective function under a greedy algorithm. Our results indicate that shorter fragments reproduce the native structure more accurately than the longer. Libraries composed of multiple fragment lengths generate even better structures, where longer fragments show to be more useful at the beginning of the simulations. The use of many different fragment sizes shows little improvement when compared to predictions carried out with libraries that comprise only three different fragment sizes. Models obtained from libraries built using only sequence similarity are, on average, better than those built with a secondary structure prediction bias. However, we found that the use of secondary structure prediction allows greater reduction of the search space, which is invaluable for prediction methods. The results of this study can be critical guidelines for the use of fragment libraries in protein structure prediction.
Can Library Use Enhance Intercultural Education?

Science.gov (United States)

Pihl, Joron

2012-01-01

This article explores the questions to what extent educational research addresses library use in education and how the library can contribute to intercultural education. The focus is primarily on elementary education in Europe. Analysis of research publications was based on searches for peer-reviewed journals in international databases, literary…
Evaluating School Library Information Services in the Digital Age.

Science.gov (United States)

Everhart, Nancy

2000-01-01

Discusses criteria for evaluating school library information services. Highlights include types of services; physical facilities; library usage; circulation statistics; changes due to technology; fill rate, or the percentage of successful searches for library materials; OPAC (online public access catalog) reports; observation; and examining…
Accessing Digital Libraries: A Study of ARL Members' Digital Projects

Science.gov (United States)

Kahl, Chad M.; Williams, Sarah C.

2006-01-01

To ensure efficient access to and integrated searching capabilities for their institution's new digital library projects, the authors studied Web sites of the Association of Research Libraries' (ARL) 111 academic, English-language libraries. Data were gathered on 1117 digital projects, noting library Web site and project access, metadata, and…
The Evolution of Discovery Systems in Academic Libraries: A Case Study at the University of Houston Libraries

Science.gov (United States)

Guajardo, Richard; Brett, Kelsey; Young, Frederick

2017-01-01

For the past several years academic libraries have been adopting discovery systems to provide a search experience that reflects user expectations and improves access to electronic resources. University of Houston Libraries has kept pace with this evolving trend by pursuing various discovery options; these include an open-source tool, a federated…
Information-seeking behavior of basic science researchers: implications for library services.

Science.gov (United States)

Haines, Laura L; Light, Jeanene; O'Malley, Donna; Delwiche, Frances A

2010-01-01

This study examined the information-seeking behaviors of basic science researchers to inform the development of customized library services. A qualitative study using semi-structured interviews was conducted on a sample of basic science researchers employed at a university medical school. The basic science researchers used a variety of information resources ranging from popular Internet search engines to highly technical databases. They generally relied on basic keyword searching, using the simplest interface of a database or search engine. They were highly collegial, interacting primarily with coworkers in their laboratories and colleagues employed at other institutions. They made little use of traditional library services and instead performed many traditional library functions internally. Although the basic science researchers expressed a positive attitude toward the library, they did not view its resources or services as integral to their work. To maximize their use by researchers, library resources must be accessible via departmental websites. Use of library services may be increased by cultivating relationships with key departmental administrative personnel. Despite their self-sufficiency, subjects expressed a desire for centralized information about ongoing research on campus and shared resources, suggesting a role for the library in creating and managing an institutional repository.
Statistic methods for searching inundated radioactive entities

International Nuclear Information System (INIS)

Dubasov, Yu.V.; Krivokhatskij, A.S.; Khramov, N.N.

1993-01-01

The problem of searching flooded radioactive object in a present area was considered. Various models of the searching route plotting are discussed. It is shown that spiral route by random points from the centre of the area examined is the most efficient one. The conclusion is made that, when searching flooded radioactive objects, it is advisable to use multidimensional statistical methods of classification
Library of sophisticated functions for analysis of nuclear spectra

Science.gov (United States)

Morháč, Miroslav; Matoušek, Vladislav

2009-10-01

In the paper we present compact library for analysis of nuclear spectra. The library consists of sophisticated functions for background elimination, smoothing, peak searching, deconvolution, and peak fitting. The functions can process one- and two-dimensional spectra. The software described in the paper comprises a number of conventional as well as newly developed methods needed to analyze experimental data. Program summaryProgram title: SpecAnalysLib 1.1 Catalogue identifier: AEDZ_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEDZ_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 42 154 No. of bytes in distributed program, including test data, etc.: 2 379 437 Distribution format: tar.gz Programming language: C++ Computer: Pentium 3 PC 2.4 GHz or higher, Borland C++ Builder v. 6. A precompiled Windows version is included in the distribution package Operating system: Windows 32 bit versions RAM: 10 MB Word size: 32 bits Classification: 17.6 Nature of problem: The demand for advanced highly effective experimental data analysis functions is enormous. The library package represents one approach to give the physicists the possibility to use the advanced routines simply by calling them from their own programs. SpecAnalysLib is a collection of functions for analysis of one- and two-parameter γ-ray spectra, but they can be used for other types of data as well. The library consists of sophisticated functions for background elimination, smoothing, peak searching, deconvolution, and peak fitting. Solution method: The algorithms of background estimation are based on Sensitive Non-linear Iterative Peak (SNIP) clipping algorithm. The smoothing algorithms are based on the convolution of the original data with several types of filters and algorithms based on discrete
Monte-Carlo Method Python Library for dose distribution Calculation in Brachytherapy

Energy Technology Data Exchange (ETDEWEB)

Randriantsizafy, R D; Ramanandraibe, M J [Madagascar Institut National des Sciences et Techniques Nucleaires, Antananarivo (Madagascar); Raboanary, R [Institut of astro and High-Energy Physics Madagascar, University of Antananarivo, Antananarivo (Madagascar)

2007-07-01

The Cs-137 Brachytherapy treatment is performed in Madagascar since 2005. Time treatment calculation for prescribed dose is made manually. Monte-Carlo Method Python library written at Madagascar INSTN is experimentally used to calculate the dose distribution on the tumour and around it. The first validation of the code was done by comparing the library curves with the Nucletron company curves. To reduce the duration of the calculation, a Grid of PC's is set up with listner patch run on each PC. The library will be used to modelize the dose distribution in the CT scan patient picture for individual and better accuracy time calculation for a prescribed dose.
Monte-Carlo Method Python Library for dose distribution Calculation in Brachytherapy

International Nuclear Information System (INIS)

Randriantsizafy, R.D.; Ramanandraibe, M.J.; Raboanary, R.

2007-01-01

The Cs-137 Brachytherapy treatment is performed in Madagascar since 2005. Time treatment calculation for prescribed dose is made manually. Monte-Carlo Method Python library written at Madagascar INSTN is experimentally used to calculate the dose distribution on the tumour and around it. The first validation of the code was done by comparing the library curves with the Nucletron company curves. To reduce the duration of the calculation, a Grid of PC's is set up with listner patch run on each PC. The library will be used to modelize the dose distribution in the CT scan patient picture for individual and better accuracy time calculation for a prescribed dose.
Pylogeny: an open-source Python framework for phylogenetic tree reconstruction and search space heuristics

Directory of Open Access Journals (Sweden)

Alexander Safatli

2015-06-01

Full Text Available Summary. Pylogeny is a cross-platform library for the Python programming language that provides an object-oriented application programming interface for phylogenetic heuristic searches. Its primary function is to permit both heuristic search and analysis of the phylogenetic tree search space, as well as to enable the design of novel algorithms to search this space. To this end, the framework supports the structural manipulation of phylogenetic trees, in particular using rearrangement operators such as NNI, SPR, and TBR, the scoring of trees using parsimony and likelihood methods, the construction of a tree search space graph, and the programmatic execution of a few existing heuristic programs. The library supports a range of common phylogenetic file formats and can be used for both nucleotide and protein data. Furthermore, it is also capable of supporting GPU likelihood calculation on nucleotide character data through the BEAGLE library.Availability. Existing development and source code is available for contribution and for download by the public from GitHub (http://github.com/AlexSafatli/Pylogeny. A stable release of this framework is available for download through PyPi (Python Package Index at http://pypi.python.org/pypi/pylogeny.
Multi-line split DNA synthesis: a novel combinatorial method to make high quality peptide libraries

Directory of Open Access Journals (Sweden)

Ueno Shingo

2004-09-01

Full Text Available Abstract Background We developed a method to make a various high quality random peptide libraries for evolutionary protein engineering based on a combinatorial DNA synthesis. Results A split synthesis in codon units was performed with mixtures of bases optimally designed by using a Genetic Algorithm program. It required only standard DNA synthetic reagents and standard DNA synthesizers in three lines. This multi-line split DNA synthesis (MLSDS is simply realized by adding a mix-and-split process to normal DNA synthesis protocol. Superiority of MLSDS method over other methods was shown. We demonstrated the synthesis of oligonucleotide libraries with 1016 diversity, and the construction of a library with random sequence coding 120 amino acids containing few stop codons. Conclusions Owing to the flexibility of the MLSDS method, it will be able to design various "rational" libraries by using bioinformatics databases.

Search Engines for Tomorrow's Scholars

Science.gov (United States)

Fagan, Jody Condit

2011-01-01

Today's scholars face an outstanding array of choices when choosing search tools: Google Scholar, discipline-specific abstracts and index databases, library discovery tools, and more recently, Microsoft's re-launch of their academic search tool, now dubbed Microsoft Academic Search. What are these tools' strengths for the emerging needs of…
Curry’s Study on the Quality of Public Library Reference Service to LGBTQ Youth

Directory of Open Access Journals (Sweden)

Gregg A Stevens

2018-02-01

Full Text Available A Review of: Curry, A. (2005. If I ask, will they answer? Evaluating public library reference service to gay and lesbian youth. Reference & User Services Quarterly, 45(1, 65-75. Retrieved from https://www.jstor.org/journal/refuseserq Abstract Objective - To assess the quality of service provided by reference staff in public libraries when presented with a request for LGBTQ information by a young person. Design - Unobtrusive observation without informed consent. Setting - Public library branches in the greater Vancouver area, British Columbia, Canada. Subjects - Reference librarians. Methods - A 19-year-old posing as a high school student approached reference desk staff at 20 public library branches. The student proxy, “Angela”, was instructed to ask for books on forming a gay-straight alliance at her school and, if there was a full reference interview, to also ask for recommendations of novels that the group might read. She recorded the reactions, both verbal and nonverbal, using Reference and User Services Association guidelines as a template. Library administrators were aware of the potential visits and permitted the research, but the reference desk staff were not aware of a potential visit by the student proxy. The researcher claimed that her method, while deceptive, was necessary to obtain authentic reactions from the library staff. Main Results - Most reference librarians approached by Angela made adequate attempts to assist her, although a few library staff reacted negatively to her query. Half of the librarians reacted positively to the patron’s request, with most of the others providing neutral responses. Very few of the librarians actually taught the patron how to use the library’s catalog to search for materials, and most of the librarians were unable to find appropriate materials due to not knowing the appropriate search terms. Only three library staff showed overt disapproval of the search topic, such as frowning or rushing
Building a better fragment library for de novo protein structure prediction.

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Saulo H P de Oliveira

Full Text Available Fragment-based approaches are the current standard for de novo protein structure prediction. These approaches rely on accurate and reliable fragment libraries to generate good structural models. In this work, we describe a novel method for structure fragment library generation and its application in fragment-based de novo protein structure prediction. The importance of correct testing procedures in assessing the quality of fragment libraries is demonstrated. In particular, the exclusion of homologs to the target from the libraries to correctly simulate a de novo protein structure prediction scenario, something which surprisingly is not always done. We demonstrate that fragments presenting different predominant predicted secondary structures should be treated differently during the fragment library generation step and that exhaustive and random search strategies should both be used. This information was used to develop a novel method, Flib. On a validation set of 41 structurally diverse proteins, Flib libraries presents both a higher precision and coverage than two of the state-of-the-art methods, NNMake and HHFrag. Flib also achieves better precision and coverage on the set of 275 protein domains used in the two previous experiments of the the Critical Assessment of Structure Prediction (CASP9 and CASP10. We compared Flib libraries against NNMake libraries in a structure prediction context. Of the 13 cases in which a correct answer was generated, Flib models were more accurate than NNMake models for 10. "Flib is available for download at: http://www.stats.ox.ac.uk/research/proteins/resources".
Building a Better Fragment Library for De Novo Protein Structure Prediction

Science.gov (United States)

de Oliveira, Saulo H. P.; Shi, Jiye; Deane, Charlotte M.

2015-01-01

Fragment-based approaches are the current standard for de novo protein structure prediction. These approaches rely on accurate and reliable fragment libraries to generate good structural models. In this work, we describe a novel method for structure fragment library generation and its application in fragment-based de novo protein structure prediction. The importance of correct testing procedures in assessing the quality of fragment libraries is demonstrated. In particular, the exclusion of homologs to the target from the libraries to correctly simulate a de novo protein structure prediction scenario, something which surprisingly is not always done. We demonstrate that fragments presenting different predominant predicted secondary structures should be treated differently during the fragment library generation step and that exhaustive and random search strategies should both be used. This information was used to develop a novel method, Flib. On a validation set of 41 structurally diverse proteins, Flib libraries presents both a higher precision and coverage than two of the state-of-the-art methods, NNMake and HHFrag. Flib also achieves better precision and coverage on the set of 275 protein domains used in the two previous experiments of the the Critical Assessment of Structure Prediction (CASP9 and CASP10). We compared Flib libraries against NNMake libraries in a structure prediction context. Of the 13 cases in which a correct answer was generated, Flib models were more accurate than NNMake models for 10. “Flib is available for download at: http://www.stats.ox.ac.uk/research/proteins/resources”. PMID:25901595
Uncovering Web search strategies in South African higher education

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Surika Civilcharran

2016-11-01

Full Text Available Background: In spite of the enormous amount of information available on the Web and the fact that search engines are continuously evolving to enhance the search experience, students are nevertheless faced with the difficulty of effectively retrieving information. It is, therefore, imperative for the interaction between students and search tools to be understood and search strategies to be identified, in order to promote successful information retrieval. Objectives: This study identifies the Web search strategies used by postgraduate students and forms part of a wider study into information retrieval strategies used by postgraduate students at the University of KwaZulu-Natal (UKZN, Pietermaritzburg campus, South Africa. Method: Largely underpinned by Thatcher’s cognitive search strategies, the mixed-methods approach was utilised for this study, in which questionnaires were employed in Phase 1 and structured interviews in Phase 2. This article reports and reflects on the findings of Phase 2, which focus on identifying the Web search strategies employed by postgraduate students. The Phase 1 results were reported in Civilcharran, Hughes and Maharaj (2015. Results: Findings reveal the Web search strategies used for academic information retrieval. In spite of easy access to the invisible Web and the advent of meta-search engines, the use of Web search engines still remains the preferred search tool. The UKZN online library databases and especially the UKZN online library, Online Public Access Catalogue system, are being underutilised. Conclusion: Being ranked in the top three percent of the world’s universities, UKZN is investing in search tools that are not being used to their full potential. This evidence suggests an urgent need for students to be trained in Web searching and to have a greater exposure to a variety of search tools. This article is intended to further contribute to the design of undergraduate training programmes in order to deal
Illuminating choices for library prep: a comparison of library preparation methods for whole genome sequencing of Cryptococcus neoformans using Illumina HiSeq.

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Johanna Rhodes

Full Text Available The industry of next-generation sequencing is constantly evolving, with novel library preparation methods and new sequencing machines being released by the major sequencing technology companies annually. The Illumina TruSeq v2 library preparation method was the most widely used kit and the market leader; however, it has now been discontinued, and in 2013 was replaced by the TruSeq Nano and TruSeq PCR-free methods, leaving a gap in knowledge regarding which is the most appropriate library preparation method to use. Here, we used isolates from the pathogenic fungi Cryptococcus neoformans var. grubii and sequenced them using the existing TruSeq DNA v2 kit (Illumina, along with two new kits: the TruSeq Nano DNA kit (Illumina and the NEBNext Ultra DNA kit (New England Biolabs to provide a comparison. Compared to the original TruSeq DNA v2 kit, both newer kits gave equivalent or better sequencing data, with increased coverage. When comparing the two newer kits, we found little difference in cost and workflow, with the NEBNext Ultra both slightly cheaper and faster than the TruSeq Nano. However, the quality of data generated using the TruSeq Nano DNA kit was superior due to higher coverage at regions of low GC content, and more SNPs identified. Researchers should therefore evaluate their resources and the type of application (and hence data quality being considered when ultimately deciding on which library prep method to use.
Illuminating choices for library prep: a comparison of library preparation methods for whole genome sequencing of Cryptococcus neoformans using Illumina HiSeq.

Science.gov (United States)

Rhodes, Johanna; Beale, Mathew A; Fisher, Matthew C

2014-01-01

The industry of next-generation sequencing is constantly evolving, with novel library preparation methods and new sequencing machines being released by the major sequencing technology companies annually. The Illumina TruSeq v2 library preparation method was the most widely used kit and the market leader; however, it has now been discontinued, and in 2013 was replaced by the TruSeq Nano and TruSeq PCR-free methods, leaving a gap in knowledge regarding which is the most appropriate library preparation method to use. Here, we used isolates from the pathogenic fungi Cryptococcus neoformans var. grubii and sequenced them using the existing TruSeq DNA v2 kit (Illumina), along with two new kits: the TruSeq Nano DNA kit (Illumina) and the NEBNext Ultra DNA kit (New England Biolabs) to provide a comparison. Compared to the original TruSeq DNA v2 kit, both newer kits gave equivalent or better sequencing data, with increased coverage. When comparing the two newer kits, we found little difference in cost and workflow, with the NEBNext Ultra both slightly cheaper and faster than the TruSeq Nano. However, the quality of data generated using the TruSeq Nano DNA kit was superior due to higher coverage at regions of low GC content, and more SNPs identified. Researchers should therefore evaluate their resources and the type of application (and hence data quality) being considered when ultimately deciding on which library prep method to use.
100 Library Lifesavers: A Survival Guide for School Library Media Specialists.

Science.gov (United States)

Bacon, Pamela S.

This book contains tips (author's suggestions), tools (ready-to-use lifesavers), and talk (quotes from practicing media specialists) for school librarians at all grade levels. A total of 100 lifesavers are included, covering areas such as inventory, motivation strategies, disciplinary approaches, library checkout, Internet searching, the traveling…
Exposing Library Services with AngularJS

OpenAIRE

Jakob Voß; Moritz Horn

2014-01-01

This article provides an introduction to the JavaScript framework AngularJS and specific AngularJS modules for accessing library services. It shows how information such as search suggestions, additional links, and availability can be embedded in any website. The ease of reuse may encourage more libraries to expose their services via standard APIs to allow usage in different contexts.
Library of Alexandria's New Web Site

Directory of Open Access Journals (Sweden)

2004-06-01

Full Text Available A review for the new version of Library of Alexandria web site which lunched on May 2004, the review deals with general introduction to the new version , then the main 6 section of the site , and show some features of the new site, and finally talk in concentration about the library catalog on the internet and its search capabilities.
SCHOOL COMMUNITY PERCEPTION OF LIBRARY APPS AGAINTS LIBRARY EMPOWERMENT

Directory of Open Access Journals (Sweden)

Achmad Riyadi Alberto

2017-07-01

Full Text Available Abstract. This research is motivated by the development of information and communication technology (ICT in the library world so rapidly that allows libraries in the present to develop its services into digital-based services. This study aims to find out the school community’s perception of library apps developed by Riche Cynthia Johan, Hana Silvana, and Holin Sulistyo and its influence on library empowerment at the library of SD Laboratorium Percontohan UPI Bandung. Library apps in this research belong to the context of m-libraries, which is a library that meets the needs of its users by using mobile platforms such as smartphones,computers, and other mobile devices. Empowerment of library is the utilization of all aspects of the implementation of libraries to the best in order to achieve the expected goals. An analysis of the schoolcommunity’s perception of library apps using the Technology Acceptance Model (TAM includes: ease of use, usefulness, usability, usage trends, and real-use conditions. While the empowerment of the library includes aspects: information empowerment, empowerment of learning resources, empowerment of human resources, empowerment of library facilities, and library promotion. The research method used in this research is descriptive method with quantitative approach. Population and sample in this research is school community at SD Laboratorium Percontohan UPI Bandung. Determination of sample criteria by using disproportionate stratified random sampling with the number of samples of 83 respondents. Data analysis using simple linear regression to measure the influence of school community perception about library apps to library empowerment. The result of data analysis shows that there is influence between school community perception about library apps to library empowerment at library of SD Laboratorium Percontohan UPI Bandung which is proved by library acceptance level and library empowerment improvement.
Apps and Mobile Support Services in Canadian Academic Medical Libraries

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Tess Grynoch

2016-12-01

Full Text Available Objective: To examine how Canadian academic medical libraries are supporting mobile apps, what apps are currently being provided by these libraries, and what types of promotion are being used. Methods: A survey of the library websites for the 17 medical schools in Canada was completed. For each library website surveyed, the medical apps listed on the website, any services mentioned through this medium, and any type of app promotion events were noted. When Facebook and Twitter accounts were evident, the tweets were searched and the past two years of Facebook posts scanned for mention of medical apps or mobile services/events. Results: All seventeen academic medical libraries had lists of mobile medical apps with a large range in the number of medical relevant apps (average=31, median= 23. A total of 275 different apps were noted and the apps covered a wide range of subjects. Five of the 14 Facebook accounts scanned had posts about medical apps in the past two years while 11 of the 15 Twitter accounts had tweets about medical apps. Social media was only one of the many promotional methods noted. Outside of the app lists and mobile resources guides, Canadian academic medical libraries are providing workshops, presentations, and drop-in sessions for mobile medical apps. Conclusion: While librarians cannot simply compare mobile services and resources between academic medical libraries without factoring in a number of other circumstances, librarians can learn from mobile resources strategies employed at other libraries, such as using research guides to increase medical app literacy.
From Libraries to ‘Libratories’

Directory of Open Access Journals (Sweden)

Leo Waaijers

2006-04-01

Full Text Available While the eighties of the last century were a time of local automation for libraries and the nineties the decade in which libraries embraced the internet and the WWW, now is the age in which the big search engines and institutional repositories are gaining a firm footing. This heralds a new era in both the evolution of scholarly communication and its agencies themselves, i.e. the libraries. Until now libraries and publishers have developed a digital variant of existing processes and products, i.e. catalogues posted on the Web, scanned copies of articles, e-mail notification about acquisitions or expired lending periods, or traditional journals in a digital jacket. However, the new OAI repositories and services based upon them have given rise to entirely new processes and products, libraries transforming themselves into partners in setting up virtual learning environments, building an institution’s digital showcase, maintaining academics’ personal websites, designing refereed portals and – further into the future – taking part in organising virtual research environments or collaboratories. Libraries are set to metamorphose into ‘libratories’, an imaginary word to express their combined functions of library, repository and collaboratory. In such environments scholarly communication will be liberated from its current copyright bridle while its coverage will be both broader - including primary data, audiovisuals and dynamic models - and deeper, with cross-disciplinary analyses of methodologies and applications of instruments. Universities will make it compulsory to store in their institutional repositories the results of research conducted within their walls for purposes of academic reporting, review committees, and other modes of clarification and explanation. Big search engines will provide access to this profusion of information and organise its mass customisation.
ARSTEC, Nonlinear Optimization Program Using Random Search Method

International Nuclear Information System (INIS)

Rasmuson, D. M.; Marshall, N. H.

1979-01-01

1 - Description of problem or function: The ARSTEC program was written to solve nonlinear, mixed integer, optimization problems. An example of such a problem in the nuclear industry is the allocation of redundant parts in the design of a nuclear power plant to minimize plant unavailability. 2 - Method of solution: The technique used in ARSTEC is the adaptive random search method. The search is started from an arbitrary point in the search region and every time a point that improves the objective function is found, the search region is centered at that new point. 3 - Restrictions on the complexity of the problem: Presently, the maximum number of independent variables allowed is 10. This can be changed by increasing the dimension of the arrays
Developing online research strategies for library users at Sokoine ...

African Journals Online (AJOL)

Wanyenda

SNAL develop effective online search strategies that help them make effective use of ... “trained in the application of information resources of their work”. ... However, the library has now migrated to an integrated web-based library automation.
Bridging the Gulf: Mixed Methods and Library Service Evaluation

Science.gov (United States)

Haynes, Abby

2004-01-01

This paper explores library evaluation in Australia and proposes a return to research fundamentals in which evaluators are asked to consider the centrality of philosophical issues and the role of different research methods. A critique of current evaluation examples demonstrates a system-centred, quantitative, input/output focus which fails to…
TRITON, 3-D Multi-Region Neutron Diffusion Burnup with Criticality Search

International Nuclear Information System (INIS)

1974-01-01

1 - Nature of physical problem solved: TRITON is a multigroup diffusion depletion program in three dimensions (x,y,z). In addition to the straight K eff calculation, three types of criticality searches are possible - diluted control isotope search, region-wise smeared control isotope search, region-wise smeared control isotope search, region-wise smeared control isotope boundary search (the control isotope can be smeared over one region or over a group of regions called a control bank). The depletion equations are solved region-wise. More than one microscopic cross section library can be used in the various regions of the reactor. The same is true for self-shielding factors. Such sets of data can be changed at pre-determined time steps. 2 - Method of solution: The mathematical model employed for the solution of the finite difference equations, which is derived from a seven-point approximation of diffusion equations, is an on-line Chebyshev semi- iterative method. 3 - Restrictions on the complexity of the problem: Maximum number of: library sets: 1; self-shielding sets: 10; compositions: 100; self-shielding coefficients: 6000; groups: 10; fuel isotopes: 30; fission products: 29; isotopes: 50; burnable isotopes: 40; control banks: 100; mesh points: 15000; regions: 400; time steps: 100; control areas: 100; small time steps: 200; elements in the control list: 400; x planes: 100; y planes: 100; z planes: 100
Content and Design Features of Academic Health Sciences Libraries' Home Pages.

Science.gov (United States)

McConnaughy, Rozalynd P; Wilson, Steven P

2018-01-01

The goal of this content analysis was to identify commonly used content and design features of academic health sciences library home pages. After developing a checklist, data were collected from 135 academic health sciences library home pages. The core components of these library home pages included a contact phone number, a contact email address, an Ask-a-Librarian feature, the physical address listed, a feedback/suggestions link, subject guides, a discovery tool or database-specific search box, multimedia, social media, a site search option, a responsive web design, and a copyright year or update date.
The Search for Meaning of Life in Mitch Albom's Tuesdays with Morrie

OpenAIRE

Rahmahwati, Ummu

2014-01-01

People often realize that they need to search the meaning of their life. The main character in the novel Mitch Albom's Tuesdays with Morrie, Morrie, exemplifies the process of this searching the meaning of life. This study is designed for analyzing how Morrie searches the meaning in life and how this process also influences the supporting character, Mitch, who tries to grasp the meaning in his life. The methods used in this study are library research and psychological approach that relate to ...
Application of pulse pile-up correction spectrum to the library least-squares method

Energy Technology Data Exchange (ETDEWEB)

Lee, Sang Hoon [Kyungpook National Univ., Daegu (Korea, Republic of)

2006-12-15

The Monte Carlo simulation code CEARPPU has been developed and updated to provide pulse pile-up correction spectra for high counting rate cases. For neutron activation analysis, CEARPPU correction spectra were used in library least-squares method to give better isotopic activity results than the convention library least-squares fitting with uncorrected spectra.

Real-time earthquake monitoring using a search engine method.

Science.gov (United States)

Zhang, Jie; Zhang, Haijiang; Chen, Enhong; Zheng, Yi; Kuang, Wenhuan; Zhang, Xiong

2014-12-04

When an earthquake occurs, seismologists want to use recorded seismograms to infer its location, magnitude and source-focal mechanism as quickly as possible. If such information could be determined immediately, timely evacuations and emergency actions could be undertaken to mitigate earthquake damage. Current advanced methods can report the initial location and magnitude of an earthquake within a few seconds, but estimating the source-focal mechanism may require minutes to hours. Here we present an earthquake search engine, similar to a web search engine, that we developed by applying a computer fast search method to a large seismogram database to find waveforms that best fit the input data. Our method is several thousand times faster than an exact search. For an Mw 5.9 earthquake on 8 March 2012 in Xinjiang, China, the search engine can infer the earthquake's parameters in <1 s after receiving the long-period surface wave data.
Danish Post‐Secondary Students Use Public Libraries for Study Purposes. A review of: Pors, Niels Ole. “The Public Library and Students’ Information Needs.” New Library World 107.1226/12272 (2006: 275‐85.

Directory of Open Access Journals (Sweden)

Julie McKenna

2007-09-01

Full Text Available Objective – To determine whether and how Danish university and higher education students use public libraries for studypurposes.Design – Online survey.Setting – Post‐secondary programs in Denmark.Subjects – 1,575 students in university‐level programs or other higher education programs (vocational three‐to‐four‐year programs in Denmark.Methods – A sample of students was drawn from the national database of students by selecting every student born on the 15th of every month (approximately 4,900 students. A letter describing the study and with an invitation to fill out an online questionnaire was sent to all students in the sample. There were 1,694 valid responses (approximately 35% response rate. Students following short vocational programs were deemed to be under‐represented and these subjects were omitted from the analysis of this report,which reflects the response of 1,575 students. The online questionnaire gathered demographic details (gender, age, educational institution, study topic, study year, geographical location, access to the Internet, etc. and used 110 questions or statements to gather information about student information‐seeking behaviour related to study purposes. These included use of the physical library and satisfaction with services, use of search engines, awareness and use of library Web‐based services, study behaviour, and participation in information literacy activities. Main results – For the purposes of this study, “academic library is used as a generic term covering university libraries, research libraries, educational libraries and all other kind of libraries outside the field of public libraries” (p. 278. The survey results confirmed many of the previous international reports of student information‐seeking behaviour: 85% of students use the academic library for study purposes; fewer than 10% of all students are able to cope without any library use; students in technology and engineering
Automated search method for AFM and profilers

Science.gov (United States)

Ray, Michael; Martin, Yves C.

2001-08-01

A new automation software creates a search model as an initial setup and searches for a user-defined target in atomic force microscopes or stylus profilometers used in semiconductor manufacturing. The need for such automation has become critical in manufacturing lines. The new method starts with a survey map of a small area of a chip obtained from a chip-design database or an image of the area. The user interface requires a user to point to and define a precise location to be measured, and to select a macro function for an application such as line width or contact hole. The search algorithm automatically constructs a range of possible scan sequences within the survey, and provides increased speed and functionality compared to the methods used in instruments to date. Each sequence consists in a starting point relative to the target, a scan direction, and a scan length. The search algorithm stops when the location of a target is found and criteria for certainty in positioning is met. With today's capability in high speed processing and signal control, the tool can simultaneously scan and search for a target in a robotic and continuous manner. Examples are given that illustrate the key concepts.
Google Scholar Usage: An Academic Library's Experience

Science.gov (United States)

Wang, Ya; Howard, Pamela

2012-01-01

Google Scholar is a free service that provides a simple way to broadly search for scholarly works and to connect patrons with the resources libraries provide. The researchers in this study analyzed Google Scholar usage data from 2006 for three library tools at San Francisco State University: SFX link resolver, Web Access Management proxy server,…
Towards a full reference library of MS(n) spectra. II: A perspective from the library of pesticide spectra extracted from the literature/Internet.

Science.gov (United States)

Milman, Boris L; Zhurkovich, Inna K

2011-12-30

To gain perspective on building full transferable libraries of MS(n) spectra from their diverse/numerous collections, a new library was built from 1723 MS(>1) spectra (mainly MS² spectra) of 490 pesticides and related compounds. Spectra acquired on different types of tandem instruments in various experimental conditions were extracted from 168 literature articles and Internet sites. Testing of the library was based on searches where 'unknown' and reference spectra originated from different sources (mainly from different laboratories) were cross-compared. The NIST 05 MS² library was added to the reference spectra. The library searches were performed with all the test spectra or were divided into different subsamples containing (a) various numbers of replicate spectra of test compounds or (b) spectra acquired from different instrument types. Thus, the dependence of true/false search (identification) result rates on different factors was explored. The percentage of 1st rank correct identifications (true positives) for the only 'unknown' mass spectrum and two and more reference spectra and matching precursor ion m/z values was 89%. For qualified matches, above the cut-off match factor, that rate decreased to 80%. The corresponding rates based on the best match for two and more 'unknown' and reference spectral replicates were 89-94%. For quadrupole instruments, the rates were even higher: 91-95% (one 'unknown' spectrum) and 90-100% (two and more such spectra). This study shows that MS² spectral libraries generated from the numerous literature/Internet sources are not less efficient for the goal of identification of unknown compounds including pesticides than very common EI-MS¹ libraries and are almost as efficient as the most productive from current MS² spectral databases. Such libraries may be used as individual reference databases or supplements to large experimental spectral collections covering many groups of abundant compounds and different types of tandem
Constructing Effective Search Strategies for Electronic Searching.

Science.gov (United States)

Flanagan, Lynn; Parente, Sharon Campbell

Electronic databases have grown tremendously in both number and popularity since their development during the 1960s. Access to electronic databases in academic libraries was originally offered primarily through mediated search services by trained librarians; however, the advent of CD-ROM and end-user interfaces for online databases has shifted the…
Three looks at users: a comparison of methods for studying digital library use. User studies, Digital libraries, Digital music libraries, Music, Information use, Information science, Contextual inquiry, Contextual design, User research, Questionnaires, Log file analysis

Directory of Open Access Journals (Sweden)

Mark Notess

2004-01-01

Full Text Available Compares three user research methods of studying real-world digital library usage within the context of the Variations and Variations2 digital music libraries at Indiana University. After a brief description of both digital libraries, each method is described and illustrated with findings from the studies. User satisfaction questionnaires were used in two studies, one of Variations (n=30 and the other of Variations2 (n=12. Second, session activity log files were examined for 175 Variations2 sessions using both quantitative and qualitative methods. The third method, contextual inquiry, is illustrated with results from field observations of four voice students' information usage patterns. The three methods are compared in terms of expertise required; time required to set up, conduct, and analyse resulting data; and the benefits derived. Further benefits are achieved with a mixed-methods approach, combining the strengths of the methods to answer questions lingering as a result of other methods.
Library cooperation among academic libraries in Katsina state ...

African Journals Online (AJOL)

This study examined Library cooperation among academic libraries in Katsina state. Qualitative research method was adopted in carrying out this study. Interview was used as instrument for data collection. The population comprised of 7 Acquisition librarians from the schools understudy. A descriptive method of da ta ...
SWATH Mass Spectrometry Performance Using Extended Peptide MS/MS Assay Libraries*

Science.gov (United States)

Wu, Jemma X.; Song, Xiaomin; Pascovici, Dana; Zaw, Thiri; Care, Natasha; Krisp, Christoph; Molloy, Mark P.

2016-01-01

The use of data-independent acquisition methods such as SWATH for mass spectrometry based proteomics is usually performed with peptide MS/MS assay libraries which enable identification and quantitation of peptide peak areas. Reference assay libraries can be generated locally through information dependent acquisition, or obtained from community data repositories for commonly studied organisms. However, there have been no studies performed to systematically evaluate how locally generated or repository-based assay libraries affect SWATH performance for proteomic studies. To undertake this analysis, we developed a software workflow, SwathXtend, which generates extended peptide assay libraries by integration with a local seed library and delivers statistical analysis of SWATH-quantitative comparisons. We designed test samples using peptides from a yeast extract spiked into peptides from human K562 cell lysates at three different ratios to simulate protein abundance change comparisons. SWATH-MS performance was assessed using local and external assay libraries of varying complexities and proteome compositions. These experiments demonstrated that local seed libraries integrated with external assay libraries achieve better performance than local assay libraries alone, in terms of the number of identified peptides and proteins and the specificity to detect differentially abundant proteins. Our findings show that the performance of extended assay libraries is influenced by the MS/MS feature similarity of the seed and external libraries, while statistical analysis using multiple testing corrections increases the statistical rigor needed when searching against large extended assay libraries. PMID:27161445
Library Anxiety As A Great Barrier Before Effective Library Use: A General Appraisal

Directory of Open Access Journals (Sweden)

Erol Yılmaz

2011-09-01

Full Text Available Library anxiety is a subject which has been searched in international platform in its various dimensions since 1986 in which the concept was first defined. On the other hand, this important subject, in the context of this article, as of the end of 2010 year in which we concluded literature survey, has never been handled and studied on in the scope of Turkish Librarianship.2 Main purpose of this study which is the first article in which library anxiety is studied as an independent subject in the scope of Turkish Librarianship is to draw attention to the subject of library anxiety which is a great barrier for the users before the high level satisfaction relating to the library services, who are the existence reason of the libraries andfurthermore is to handle the studies prepared in the past on this subject under a general approach. Furthermore in this study, studies close to the subject in the Turkish Librarianship were handled and a general appraisal was made on the subject. At the final part of the study, place was given to some proposals which are directed towards the discussion of library anxiety in theoretical dimension within the scope of Turkish Librarianship and furthermore some proposals which are aimed to prevent and eliminate the formation of library anxiety in the users during the application (operation of the library are given place.
The Malaria in Pregnancy Library: a bibliometric review

NARCIS (Netherlands)

van Eijk, Anna M.; Hill, Jenny; Povall, Sue; Reynolds, Alison; Wong, Helen; ter Kuile, Feiko O.

2012-01-01

The Malaria in Pregnancy (MiP) Library is a bibliographic database that was created by the MiP Consortium in 2005 and is updated every four months using a standardized search protocol. A bibliometric review was conducted of the contents of the Library to determine dynamics in the type, content and
Fast radio burst search: cross spectrum vs. auto spectrum method

Science.gov (United States)

Liu, Lei; Zheng, Weimin; Yan, Zhen; Zhang, Juan

2018-06-01

The search for fast radio bursts (FRBs) is a hot topic in current radio astronomy studies. In this work, we carry out a single pulse search with a very long baseline interferometry (VLBI) pulsar observation data set using both auto spectrum and cross spectrum search methods. The cross spectrum method, first proposed in Liu et al., maximizes the signal power by fully utilizing the fringe phase information of the baseline cross spectrum. The auto spectrum search method is based on the popular pulsar software package PRESTO, which extracts single pulses from the auto spectrum of each station. According to our comparison, the cross spectrum method is able to enhance the signal power and therefore extract single pulses from data contaminated by high levels of radio frequency interference (RFI), which makes it possible to carry out a search for FRBs in regular VLBI observations when RFI is present.
Survey of Integration Cost-Adoption between Digital Library Systems in Iran

Directory of Open Access Journals (Sweden)

Mehdi Alipour-Hafezi

2013-03-01

Full Text Available The main goal of this article was identifying cost elements in syntactic integrating digital library systems in Iran. The levels of integration are content, technical, and organizational. It is obvious we could access some sub goals such as identifying current situation of information systems from the view points of data storage, needed standard outputs, and the current situation of interoperability in Iran, and suitable integration model in Iranian digital libraries. The analytical survey method was used in this research. Research population included 11 digital library systems that were used in Iranian digital libraries. In order to gather information, a researcher made questionnaire was used because of not existing standard collecting data tool. Findings demonstrated that we should search on three levels of interoperability: content, technical, and organizational level in order to identifying cost-adoption elements in syntactic interoperability. Also, findings showed that the elements of organizational level were too important level in cost-adoption elements. Also this research demonstrated that the high cost of adoption was related to libraries and their organizations.
Electronic biomedical literature search for budding researcher.

Science.gov (United States)

Thakre, Subhash B; Thakre S, Sushama S; Thakre, Amol D

2013-09-01

Search for specific and well defined literature related to subject of interest is the foremost step in research. When we are familiar with topic or subject then we can frame appropriate research question. Appropriate research question is the basis for study objectives and hypothesis. The Internet provides a quick access to an overabundance of the medical literature, in the form of primary, secondary and tertiary literature. It is accessible through journals, databases, dictionaries, textbooks, indexes, and e-journals, thereby allowing access to more varied, individualised, and systematic educational opportunities. Web search engine is a tool designed to search for information on the World Wide Web, which may be in the form of web pages, images, information, and other types of files. Search engines for internet-based search of medical literature include Google, Google scholar, Scirus, Yahoo search engine, etc., and databases include MEDLINE, PubMed, MEDLARS, etc. Several web-libraries (National library Medicine, Cochrane, Web of Science, Medical matrix, Emory libraries) have been developed as meta-sites, providing useful links to health resources globally. A researcher must keep in mind the strengths and limitations of a particular search engine/database while searching for a particular type of data. Knowledge about types of literature, levels of evidence, and detail about features of search engine as available, user interface, ease of access, reputable content, and period of time covered allow their optimal use and maximal utility in the field of medicine. Literature search is a dynamic and interactive process; there is no one way to conduct a search and there are many variables involved. It is suggested that a systematic search of literature that uses available electronic resource effectively, is more likely to produce quality research.
The Energy Science and Technology Database on a local library system: A case study at the Los Alamos National Research Library

Energy Technology Data Exchange (ETDEWEB)

Holtkamp, I.S.

1994-10-01

This paper presents an overview of efforts at Los Alamos National Laboratory to acquire and mount the Energy Science and Technology Database (EDB) as a citation database on the Research Library`s Geac Advance system. The rationale for undertaking this project and expected benefits are explained. Significant issues explored are loading non-USMARC records into a MARC-based library system, the use of EDB records to replace or supplement in-house cataloging of technical reports, the impact of different cataloging standards and database size on searching and retrieval, and how integrating an external database into the library`s online catalog may affect staffing and workflow.
User Requirements Analysis For Digital Library Application Using Quality Function Deployment.

Science.gov (United States)

Wulandari, Lily; Sularto, Lana; Yusnitasari, Tristyanti; Ikasari, Diana

2017-03-01

This study attemp to build Smart Digital Library to be used by the wider community wherever they are. The system is built in the form of Smart Digital Library portal which uses semantic similarity method (Semantic Similarity) to search journals, articles or books by title or author name. This method is also used to determine the recommended books to be read by visitors of Smart Digital Library based on testimony from a previous reader automatically. Steps being taken in the development of Smart Digital Library system is the analysis phase, design phase, testing and implementation phase. At this stage of the analysis using WebQual for the preparation of the instruments to be distributed to the respondents and the data obtained from the respondents will be processed using Quality Function Deployment. In the analysis phase has the purpose of identifying consumer needs and technical requirements. The analysis was performed to a digital library on the web digital library Gunadarma University, Bogor Institute of Agriculture, University of Indonesia, etc. The questionnaire was distributed to 200 respondents. The research methodology begins with the collection of user requirements and analyse it using QFD. Application design is funded by the government through a program of Featured Universities Research by the Directorate General of Higher Education (DIKTI). Conclusions from this research are identified which include the Consumer Requirements of digital library application. The elements of the consumers requirements consists of 13 elements and 25 elements of Engineering Characteristics digital library requirements. Therefore the design of digital library applications that will be built, is designed according to the findings by eliminating features that are not needed by restaurant based on QFD House of Quality.
News from the Library: Browse Library books directly from your desktop

CERN Multimedia

CERN Library

2011-01-01

The collection of electronic books held by the Library is steadily expanding, but there are still many titles not available online. However, to some extent Google is bridging the gap. Google Books is an initiative launched by Google in 2004, in collaboration with a range of publishers and large libraries, which provides the books online and enables searches of the text from cover to cover. For titles that are out of copyright, or in cases where Google has struck an agreement with the publisher, the entire books can be read online. For other books, users can still search in the entire text but, depending on the agreement reached with the publisher, they may only be able to read a limited amount of pages (limited preview) or a few lines of text (known as snippets). Google Books also provides additional information such as reviews and links to related titles. Today, there are more than 15 million scanned books in Google Books. Over the last few weeks, Google Books has been "mashed up&...
Pep-3D-Search: a method for B-cell epitope prediction based on mimotope analysis.

Science.gov (United States)

Huang, Yan Xin; Bao, Yong Li; Guo, Shu Yan; Wang, Yan; Zhou, Chun Guang; Li, Yu Xin

2008-12-16

The prediction of conformational B-cell epitopes is one of the most important goals in immunoinformatics. The solution to this problem, even if approximate, would help in designing experiments to precisely map the residues of interaction between an antigen and an antibody. Consequently, this area of research has received considerable attention from immunologists, structural biologists and computational biologists. Phage-displayed random peptide libraries are powerful tools used to obtain mimotopes that are selected by binding to a given monoclonal antibody (mAb) in a similar way to the native epitope. These mimotopes can be considered as functional epitope mimics. Mimotope analysis based methods can predict not only linear but also conformational epitopes and this has been the focus of much research in recent years. Though some algorithms based on mimotope analysis have been proposed, the precise localization of the interaction site mimicked by the mimotopes is still a challenging task. In this study, we propose a method for B-cell epitope prediction based on mimotope analysis called Pep-3D-Search. Given the 3D structure of an antigen and a set of mimotopes (or a motif sequence derived from the set of mimotopes), Pep-3D-Search can be used in two modes: mimotope or motif. To evaluate the performance of Pep-3D-Search to predict epitopes from a set of mimotopes, 10 epitopes defined by crystallography were compared with the predicted results from a Pep-3D-Search: the average Matthews correlation coefficient (MCC), sensitivity and precision were 0.1758, 0.3642 and 0.6948. Compared with other available prediction algorithms, Pep-3D-Search showed comparable MCC, specificity and precision, and could provide novel, rational results. To verify the capability of Pep-3D-Search to align a motif sequence to a 3D structure for predicting epitopes, 6 test cases were used. The predictive performance of Pep-3D-Search was demonstrated to be superior to that of other similar programs
Current status of information literacy instruction practices in medical libraries of Pakistan.

Science.gov (United States)

Ullah, Midrar; Ameen, Kanwal

2014-10-01

The research explored the current practices of information literacy (IL) instruction in medical libraries of Pakistan. A semi-structured questionnaire was mailed to the head librarians of all 114 academic medical libraries in Pakistan. It investigated the types of IL instruction provided, topics covered, methods of delivery and assessment, level of integration in the curriculum, and level of collaboration with teaching staff. The study revealed that 74% of the respondents had offered some types of IL instruction in their institutions during the previous year, ranging from library orientation to research-level skills. IL instruction is typically only offered to new students or first-time library users or on demand. A majority of the respondents developed IL instruction programs without faculty involvement. Librarians were primarily responsible for offering IL instruction in medical institutions. Face-to-face instruction in computer labs or lecture halls and individual instruction at reference desks were identified as the most common IL instruction delivery methods. The data indicated that oral feedback, written feedback, and searching in a computer lab were the most popular assessment methods that medical librarians used. IL instruction activities in medical libraries of Pakistan are in their infancy. Medical librarians also lack systematic approaches to IL instruction. Medical librarians need to develop educational partnerships with faculty for integrating IL instruction into the mainstream curriculum.
Search without Boundaries Using Simple APIs

Science.gov (United States)

Tong, Qi (Helen)

2009-01-01

The U.S. Geological Survey (USGS) Library, where the author serves as the digital services librarian, is increasingly challenged to make it easier for users to find information from many heterogeneous information sources. Information is scattered throughout different software applications (i.e., library catalog, federated search engine, link…

Selecting and Using Information Sources: Source Preferences and Information Pathways of Israeli Library and Information Science Students

Science.gov (United States)

Bronstein, Jenny

2010-01-01

Introduction: The study investigated the source preference criteria of library and information science students for their academic and personal information needs. Method: The empirical study was based on two methods of data collection. Eighteen participants wrote a personal diary for four months in which they recorded search episodes and answered…
Surveys of Online Information Service in Large Public Libraries.

Science.gov (United States)

Woy, James B.

1983-01-01

Reports results of 1983 survey of 25 public libraries and 1981 survey of 11 public libraries, both of which focused on facets of online information services--user fees, databases, documentation, equipment, miscellaneous services, and subject areas searched. The 1983 questionnaire and seven sources are appended. (EJS)
Open Search Environments: The Free Alternative to Commercial Search Services

Directory of Open Access Journals (Sweden)

Adrian O'Riordan

2014-06-01

Full Text Available Open search systems present a free and less restricted alternative to commercial search services. This paper explores the space of open search technology looking in particular at the issue of interoperability. A description of current protocols and formats for engineering open search applications is presented. The suitability of these technologies and issues around their adoption and operation are discussed. This open search approach is especially proving a fitting choice in applications involving the harvesting of resources and information integration. Principal among the technological solutions are OpenSearch and SRU. OpenSearch and SRU implement a federated model to enable existing and new search engines and search clients communicate. Applications and instances where Opensearch and SRU can be combined are presented. Other relevant technologies such as OpenURL, Apache Solr, and OAI-PMH are also discussed. The deployment of these freely licensed open standards in digital library applications is now a genuine alternative to commercial or proprietary systems.
Similarity searching and scaffold hopping in synthetically accessible combinatorial chemistry spaces.

Science.gov (United States)

Boehm, Markus; Wu, Tong-Ying; Claussen, Holger; Lemmen, Christian

2008-04-24

Large collections of combinatorial libraries are an integral element in today's pharmaceutical industry. It is of great interest to perform similarity searches against all virtual compounds that are synthetically accessible by any such library. Here we describe the successful application of a new software tool CoLibri on 358 combinatorial libraries based on validated reaction protocols to create a single chemistry space containing over 10 (12) possible products. Similarity searching with FTrees-FS allows the systematic exploration of this space without the need to enumerate all product structures. The search result is a set of virtual hits which are synthetically accessible by one or more of the existing reaction protocols. Grouping these virtual hits by their synthetic protocols allows the rapid design and synthesis of multiple follow-up libraries. Such library ideas support hit-to-lead design efforts for tasks like follow-up from high-throughput screening hits or scaffold hopping from one hit to another attractive series.
CORALINA: a universal method for the generation of gRNA libraries for CRISPR-based screening.

Science.gov (United States)

Köferle, Anna; Worf, Karolina; Breunig, Christopher; Baumann, Valentin; Herrero, Javier; Wiesbeck, Maximilian; Hutter, Lukas H; Götz, Magdalena; Fuchs, Christiane; Beck, Stephan; Stricker, Stefan H

2016-11-14

The bacterial CRISPR system is fast becoming the most popular genetic and epigenetic engineering tool due to its universal applicability and adaptability. The desire to deploy CRISPR-based methods in a large variety of species and contexts has created an urgent need for the development of easy, time- and cost-effective methods enabling large-scale screening approaches. Here we describe CORALINA (comprehensive gRNA library generation through controlled nuclease activity), a method for the generation of comprehensive gRNA libraries for CRISPR-based screens. CORALINA gRNA libraries can be derived from any source of DNA without the need of complex oligonucleotide synthesis. We show the utility of CORALINA for human and mouse genomic DNA, its reproducibility in covering the most relevant genomic features including regulatory, coding and non-coding sequences and confirm the functionality of CORALINA generated gRNAs. The simplicity and cost-effectiveness make CORALINA suitable for any experimental system. The unprecedented sequence complexities obtainable with CORALINA libraries are a necessary pre-requisite for less biased large scale genomic and epigenomic screens.
Practical fulltext search in medical records

Directory of Open Access Journals (Sweden)

Vít Volšička

2015-09-01

Full Text Available Performing a search through previously existing documents, including medical reports, is an integral part of acquiring new information and educational processes. Unfortunately, finding relevant information is not always easy, since many documents are saved in free text formats, thereby making it difficult to search through them. A full-text search is a viable solution for searching through documents. The full-text search makes it possible to efficiently search through large numbers of documents and to find those that contain specific search phrases in a short time. All leading database systems currently offer full-text search, but some do not support the complex morphology of the Czech language. Apache Solr provides full support options and some full-text libraries. This programme provides the good support of the Czech language in the basic installation, and a wide range of settings and options for its deployment over any platform. The library had been satisfactorily tested using real data from the hospitals. Solr provided useful, fast, and accurate searches. However, there is still a need to make adjustments in order to receive effective search results, particularly by correcting typographical errors made not only in the text, but also when entering words in the search box and creating a list of frequently used abbreviations and synonyms for more accurate results.
Evidence-based Medicine Search: a customizable federated search engine.

Science.gov (United States)

Bracke, Paul J; Howse, David K; Keim, Samuel M

2008-04-01

This paper reports on the development of a tool by the Arizona Health Sciences Library (AHSL) for searching clinical evidence that can be customized for different user groups. The AHSL provides services to the University of Arizona's (UA's) health sciences programs and to the University Medical Center. Librarians at AHSL collaborated with UA College of Medicine faculty to create an innovative search engine, Evidence-based Medicine (EBM) Search, that provides users with a simple search interface to EBM resources and presents results organized according to an evidence pyramid. EBM Search was developed with a web-based configuration component that allows the tool to be customized for different specialties. Informal and anecdotal feedback from physicians indicates that EBM Search is a useful tool with potential in teaching evidence-based decision making. While formal evaluation is still being planned, a tool such as EBM Search, which can be configured for specific user populations, may help lower barriers to information resources in an academic health sciences center.
Students As Stakeholders: Library Advisory Boards and Privileging Our Users

Directory of Open Access Journals (Sweden)

Erin Dorney

2013-02-01

Full Text Available In Brief: This article investigates the idea of library student advisory boards as mechanisms for building more student-centered libraries at colleges and universities. Benefits of these types of organizations, measures of success, and the importance of acting on evidence-based user feedback are discussed. Introduction A Google search for “library student advisory board” returns hundreds of results [...
Efficient searching in meshfree methods

Science.gov (United States)

Olliff, James; Alford, Brad; Simkins, Daniel C.

2018-04-01

Meshfree methods such as the Reproducing Kernel Particle Method and the Element Free Galerkin method have proven to be excellent choices for problems involving complex geometry, evolving topology, and large deformation, owing to their ability to model the problem domain without the constraints imposed on the Finite Element Method (FEM) meshes. However, meshfree methods have an added computational cost over FEM that come from at least two sources: increased cost of shape function evaluation and the determination of adjacency or connectivity. The focus of this paper is to formally address the types of adjacency information that arises in various uses of meshfree methods; a discussion of available techniques for computing the various adjacency graphs; propose a new search algorithm and data structure; and finally compare the memory and run time performance of the methods.
The commission errors search and assessment (CESA) method

Energy Technology Data Exchange (ETDEWEB)

Reer, B.; Dang, V. N

2007-05-15

Errors of Commission (EOCs) refer to the performance of inappropriate actions that aggravate a situation. In Probabilistic Safety Assessment (PSA) terms, they are human failure events that result from the performance of an action. This report presents the Commission Errors Search and Assessment (CESA) method and describes the method in the form of user guidance. The purpose of the method is to identify risk-significant situations with a potential for EOCs in a predictive analysis. The main idea underlying the CESA method is to catalog the key actions that are required in the procedural response to plant events and to identify specific scenarios in which these candidate actions could erroneously appear to be required. The catalog of required actions provides a basis for a systematic search of context-action combinations. To focus the search towards risk-significant scenarios, the actions that are examined in the CESA search are prioritized according to the importance of the systems and functions that are affected by these actions. The existing PSA provides this importance information; the Risk Achievement Worth or Risk Increase Factor values indicate the systems/functions for which an EOC contribution would be more significant. In addition, the contexts, i.e. PSA scenarios, for which the EOC opportunities are reviewed are also prioritized according to their importance (top sequences or cut sets). The search through these context-action combinations results in a set of EOC situations to be examined in detail. CESA has been applied in a plant-specific pilot study, which showed the method to be feasible and effective in identifying plausible EOC opportunities. This experience, as well as the experience with other EOC analyses, showed that the quantification of EOCs remains an issue. The quantification difficulties and the outlook for their resolution conclude the report. (author)
The commission errors search and assessment (CESA) method

International Nuclear Information System (INIS)

Reer, B.; Dang, V. N.

2007-05-01

Errors of Commission (EOCs) refer to the performance of inappropriate actions that aggravate a situation. In Probabilistic Safety Assessment (PSA) terms, they are human failure events that result from the performance of an action. This report presents the Commission Errors Search and Assessment (CESA) method and describes the method in the form of user guidance. The purpose of the method is to identify risk-significant situations with a potential for EOCs in a predictive analysis. The main idea underlying the CESA method is to catalog the key actions that are required in the procedural response to plant events and to identify specific scenarios in which these candidate actions could erroneously appear to be required. The catalog of required actions provides a basis for a systematic search of context-action combinations. To focus the search towards risk-significant scenarios, the actions that are examined in the CESA search are prioritized according to the importance of the systems and functions that are affected by these actions. The existing PSA provides this importance information; the Risk Achievement Worth or Risk Increase Factor values indicate the systems/functions for which an EOC contribution would be more significant. In addition, the contexts, i.e. PSA scenarios, for which the EOC opportunities are reviewed are also prioritized according to their importance (top sequences or cut sets). The search through these context-action combinations results in a set of EOC situations to be examined in detail. CESA has been applied in a plant-specific pilot study, which showed the method to be feasible and effective in identifying plausible EOC opportunities. This experience, as well as the experience with other EOC analyses, showed that the quantification of EOCs remains an issue. The quantification difficulties and the outlook for their resolution conclude the report. (author)
Next-generation sequencing library preparation method for identification of RNA viruses on the Ion Torrent Sequencing Platform.

Science.gov (United States)

Chen, Guiqian; Qiu, Yuan; Zhuang, Qingye; Wang, Suchun; Wang, Tong; Chen, Jiming; Wang, Kaicheng

2018-05-09

Next generation sequencing (NGS) is a powerful tool for the characterization, discovery, and molecular identification of RNA viruses. There were multiple NGS library preparation methods published for strand-specific RNA-seq, but some methods are not suitable for identifying and characterizing RNA viruses. In this study, we report a NGS library preparation method to identify RNA viruses using the Ion Torrent PGM platform. The NGS sequencing adapters were directly inserted into the sequencing library through reverse transcription and polymerase chain reaction, without fragmentation and ligation of nucleic acids. The results show that this method is simple to perform, able to identify multiple species of RNA viruses in clinical samples.
Evaluating Public Libraries Using Standard Scores: The Library Quotient.

Science.gov (United States)

O'Connor, Daniel O.

1982-01-01

Describes a method for assessing the performance of public libraries using a standardized scoring system and provides an analysis of public library data from New Jersey as an example. Library standards and the derivation of measurement ratios are also discussed. A 33-item bibliography and three data tables are included. (JL)
Job Search Methods: Consequences for Gender-based Earnings Inequality.

Science.gov (United States)

Huffman, Matt L.; Torres, Lisa

2001-01-01

Data from adults in Atlanta, Boston, and Los Angeles (n=1,942) who searched for work using formal (ads, agencies) or informal (networks) methods indicated that type of method used did not contribute to the gender gap in earnings. Results do not support formal job search as a way to reduce gender inequality. (Contains 55 references.) (SK)
Library

OpenAIRE

Dulaney, Ronald E. Jr.

1997-01-01

This study began with the desire to design a public town library of the future and became a search for an inkling of what is essential to Architecture. It is murky and full of contradictions. It asks more than it proposes, and the traces of its windings are better ordered through collage than logical synthesis. This study is neither a thesis nor a synthesis. When drawing out the measure of this study it may be beneficial to state what it attempts to place at the ...
Automated design of degenerate codon libraries.

Science.gov (United States)

Mena, Marco A; Daugherty, Patrick S

2005-12-01

Degenerate codon libraries are frequently used in protein engineering and evolution studies but are often limited to targeting a small number of positions to adequately limit the search space. To mitigate this, codon degeneracy can be limited using heuristics or previous knowledge of the targeted positions. To automate design of libraries given a set of amino acid sequences, an algorithm (LibDesign) was developed that generates a set of possible degenerate codon libraries, their resulting size, and their score relative to a user-defined scoring function. A gene library of a specified size can then be constructed that is representative of the given amino acid distribution or that includes specific sequences or combinations thereof. LibDesign provides a new tool for automated design of high-quality protein libraries that more effectively harness existing sequence-structure information derived from multiple sequence alignment or computational protein design data.
E-Library and Traditonal Library Resources Usage: A Comparative ...

African Journals Online (AJOL)

A comparative usage of e-library and traditional resources in Nigerian libraries was examined in this study. A descriptive survey method was adopted and a purposive sampling technique was used to select the sample and the process produced 125 academic, research, and public libraries in Nigeria. A total of 116 cases ...
Library Networks and Electronic Publishing.

Science.gov (United States)

Olvey, Lee D.

1995-01-01

Provides a description of present and proposed plans and strategies of OCLC (Online Computer Library Center) and their relationship to electronic publishing. FirstSearch (end-user access to secondary information), GUIDON (electronic journals online) and FastDoc (document delivery) are emphasized. (JKP)
Search and foraging behaviors from movement data: A comparison of methods.

Science.gov (United States)

Bennison, Ashley; Bearhop, Stuart; Bodey, Thomas W; Votier, Stephen C; Grecian, W James; Wakefield, Ewan D; Hamer, Keith C; Jessopp, Mark

2018-01-01

Search behavior is often used as a proxy for foraging effort within studies of animal movement, despite it being only one part of the foraging process, which also includes prey capture. While methods for validating prey capture exist, many studies rely solely on behavioral annotation of animal movement data to identify search and infer prey capture attempts. However, the degree to which search correlates with prey capture is largely untested. This study applied seven behavioral annotation methods to identify search behavior from GPS tracks of northern gannets ( Morus bassanus ), and compared outputs to the occurrence of dives recorded by simultaneously deployed time-depth recorders. We tested how behavioral annotation methods vary in their ability to identify search behavior leading to dive events. There was considerable variation in the number of dives occurring within search areas across methods. Hidden Markov models proved to be the most successful, with 81% of all dives occurring within areas identified as search. k -Means clustering and first passage time had the highest rates of dives occurring outside identified search behavior. First passage time and hidden Markov models had the lowest rates of false positives, identifying fewer search areas with no dives. All behavioral annotation methods had advantages and drawbacks in terms of the complexity of analysis and ability to reflect prey capture events while minimizing the number of false positives and false negatives. We used these results, with consideration of analytical difficulty, to provide advice on the most appropriate methods for use where prey capture behavior is not available. This study highlights a need to critically assess and carefully choose a behavioral annotation method suitable for the research question being addressed, or resulting species management frameworks established.
Canadian Public Library Users are Unaware of Their Information Literacy Deficiencies as Related to Internet Use and Public Libraries are Challenged to Address These Needs. A Review of: Julien, Heidi and Cameron Hoffman. “Information Literacy Training in Canada’s Public Libraries.” Library Quarterly 78.1 (2008: 19‐41.

Directory of Open Access Journals (Sweden)

Martha Ingrid Preddie

2009-12-01

Full Text Available Objective – To examine the role of Canada’s public libraries in information literacy skills training, and to ascertain the perspectives of public library Internet users with regard to their experiences of information literacy.Design – Qualitative research using semi‐structured interviews and observations.Setting – Five public libraries in Canada.Subjects – Twenty‐eight public library staff members and twenty‐five customers. Methods – This study constituted the second phase of a detailed examination of information literacy (IL training in Canadian public libraries. Five public libraries located throughout Canada were selected for participation. These comprised a large central branch of a public library located in a town with a population of approximately two million, a main branch of a public library in an urban city of about one million people, a public library in a town with a population of about 75,000, a library in a town of 900 people and a public library located in the community center of a Canadian First Nations reserve that housed a population of less than 100 persons. After notifying customers via signage posted in the vicinity of computers and Internet access areas, the researchers observed each patron as they accessed the Internet via library computers. Observations focused on the general physical environment of the Internet access stations, customer activities and use of the Internet, as well as the nature and degree of customer interactions with each other and with staff. Photographs were also taken and observations were recorded via field notes. The former were analyzed via qualitative content analysis while quantitative analysis was applied to the observations. Additionally, each observed participant was interviewed immediately following Internet use. Interview questions focused on a range of issues including the reasons why customers used the Internet in public libraries, customers’ perceptions about their

Digital Libraries and Repositories in India: An Evaluative Study

Science.gov (United States)

Mittal, Rekha; Mahesh, G.

2008-01-01

Purpose: The purpose of this research is to identify and evaluate the collections within digital libraries and repositories in India available in the public domain. Design/methodology/approach: The digital libraries and repositories were identified through a study of the literature, as well as internet searching and browsing. The resulting digital…
The Safari E-Book Route through the ICT Jungle: Experiences at Hillingdon Libraries

Science.gov (United States)

Fernandes, Derrick

2007-01-01

Purpose: The paper seeks to describe the provision of access to the Safari Tech Books collection of e-books at Hillingdon Libraries. Design/methodology/approach: Details are given of how the e-books collection is part of a broader range of e-information services provided by Hillingdon. Methods of searching for e-books are described, with…
USE OF METRIC METHODS OF RESEARCH IN THE LIBRARY OF VINNYTSIA STATE PEDAGOGICAL UNIVERSITY NAMED AFTER MYKHAILO KOTSIUBYNSKY

Directory of Open Access Journals (Sweden)

В. С. Білоус

2017-10-01

Full Text Available Subject. Theme. The aim of the work. The level of development of science and technology is crucial to the progress of society. The need to increase the presence of science in the global scientific information space, increase its influence in the world. The use of metric methods of research in the library of a higher school. Methods. The use of scientific methods of analysis, synthesis, analogy, comparison, forecasting allowed us to examine the results of implementation of innovative communications initiatives in the library of the university Results. Current and future activities of the library of the higher school in integration of scientific publications to international information space are highlighted. The practical implementation of these activities are discussed on the example of the libraries of Vinnitsa State M. Kotsiubynskyi Pedagogical University. Scientific novelty. The role of the university library in the process of increasing the representation of the Ukrainian science in the world of scholarly communication. The proposed strategy, the implementation of which should characterize a modern librarian as a «role model» for the community of the university in the implementation of electronic models of scientific communication. Conclusions. Innovative transformations in the content, forms and methods of library activities, using metric measurements affect the improvement of scientific activities of the institution, give significant social results. Introduction to the practice of library activities certain areas will prevent the «dissipation» of documentary scientific information resources of the university, will contribute to their consolidating, will increase the importance of scientific publications and the authority of the Ukrainian science in General. The article reflects the innovative activities of libraries inVinnytsiaMykhailoKotsiubynskyiStatePedagogicalUniversity, development of library service in using research work of the
309 Enhancing the Acquisition Methods of School Library ...

African Journals Online (AJOL)

User

2010-10-17

Oct 17, 2010 ... Sometime, the school Libraries receives cash donations for the acquisition of library materials. ... To keep financial record or book budget. (v). To keep records .... management systems to knowledge-based systems provides a.
A rational workflow for sequential virtual screening of chemical libraries on searching for new tyrosinase inhibitors.

Science.gov (United States)

Le-Thi-Thu, Huong; Casanola-Martín, Gerardo M; Marrero-Ponce, Yovani; Rescigno, Antonio; Abad, Concepcion; Khan, Mahmud Tareq Hassan

2014-01-01

The tyrosinase is a bifunctional, copper-containing enzyme widely distributed in the phylogenetic tree. This enzyme is involved in the production of melanin and some other pigments in humans, animals and plants, including skin pigmentations in mammals, and browning process in plants and vegetables. Therefore, enzyme inhibitors has been under the attention of the scientist community, due to its broad applications in food, cosmetic, agricultural and medicinal fields, to avoid the undesirable effects of abnormal melanin overproduction. However, the research of novel chemical with antityrosinase activity demands the use of more efficient tools to speed up the tyrosinase inhibitors discovery process. This chapter is focused in the different components of a predictive modeling workflow for the identification and prioritization of potential new compounds with activity against the tyrosinase enzyme. In this case, two structure chemical libraries Spectrum Collection and Drugbank are used in this attempt to combine different virtual screening data mining techniques, in a sequential manner helping to avoid the usually expensive and time consuming traditional methods. Some of the sequential steps summarize here comprise the use of drug-likeness filters, similarity searching, classification and potency QSAR multiclassifier systems, modeling molecular interactions systems, and similarity/diversity analysis. Finally, the methodologies showed here provide a rational workflow for virtual screening hit analysis and selection as a promissory drug discovery strategy for use in target identification phase.
Assessment of statistical methods used in library-based approaches to microbial source tracking.

Science.gov (United States)

Ritter, Kerry J; Carruthers, Ethan; Carson, C Andrew; Ellender, R D; Harwood, Valerie J; Kingsley, Kyle; Nakatsu, Cindy; Sadowsky, Michael; Shear, Brian; West, Brian; Whitlock, John E; Wiggins, Bruce A; Wilbur, Jayson D

2003-12-01

Several commonly used statistical methods for fingerprint identification in microbial source tracking (MST) were examined to assess the effectiveness of pattern-matching algorithms to correctly identify sources. Although numerous statistical methods have been employed for source identification, no widespread consensus exists as to which is most appropriate. A large-scale comparison of several MST methods, using identical fecal sources, presented a unique opportunity to assess the utility of several popular statistical methods. These included discriminant analysis, nearest neighbour analysis, maximum similarity and average similarity, along with several measures of distance or similarity. Threshold criteria for excluding uncertain or poorly matched isolates from final analysis were also examined for their ability to reduce false positives and increase prediction success. Six independent libraries used in the study were constructed from indicator bacteria isolated from fecal materials of humans, seagulls, cows and dogs. Three of these libraries were constructed using the rep-PCR technique and three relied on antibiotic resistance analysis (ARA). Five of the libraries were constructed using Escherichia coli and one using Enterococcus spp. (ARA). Overall, the outcome of this study suggests a high degree of variability across statistical methods. Despite large differences in correct classification rates among the statistical methods, no single statistical approach emerged as superior. Thresholds failed to consistently increase rates of correct classification and improvement was often associated with substantial effective sample size reduction. Recommendations are provided to aid in selecting appropriate analyses for these types of data.
Assessment of Library Instruction and Library Literacy Skills of First ...

African Journals Online (AJOL)

This study investigated the effectiveness and impact of library instruction (GST 111 – the use of library) course on library literacy skills of first year undergraduate students. The study adopted the descriptive survey research method and questionnaire was used as the research instrument. First year undergraduate students of ...
The method of search of tendencies

International Nuclear Information System (INIS)

Reuss, Paul.

1981-08-01

The search of tendencies is an application of the mean squares method. Its objective is the better possible evaluation of the basic data used in the calculations from the comparison between measurements of integral characteristics and the corresponding theoretical results. This report presents the minimization which allows the estimation of the basic data and, above all, the methods which are necessary for the critical analysis of the obtained results [fr
[Modern referral-information service in the Central Medical Library of the University of Zagreb Medical School].

Science.gov (United States)

Hadjina, G; Granić, D; Bekavac, A

1990-01-01

New technologies in information and retrieval services of the Central Medical Library are presented, as well as comparison between traditional search of biomedical literature and search of biomedical bases available on CD-ROM and on-line. MeSH thesaurus represents the basis for all modes of searches, either through published indexes (Index Medicus, Biomedicina Iugoslavica), searches through on-line, or via CD-ROM technology. Experience in indexing according to MeSH structure helps us to search and retrieve biomedical literature on new media too. Great interest in new media for search and retrieval of biomedical literature among our users (100%) justifies their introduction into the Library. In the period of four months, 75% of our users chose CD-ROM technology in their search, 25% chose on-line search, and both technologies were combined by 33% of the users. Having these new media in our library we have reached the point from which we join the world biomedical information network and successfully meet the growing need for information in the field of biomedicine.
An extensible and successful method of identifying collaborators for National Library of Medicine informationist projects.

Science.gov (United States)

Williams, Jeff D; Rambo, Neil H

2015-07-01

The New York University (NYU) Health Sciences Library used a new method to arrange in-depth discussions with basic science researchers. The objective was to identify collaborators for a new National Library of Medicine administrative supplement. The research took place at the NYU Health Sciences Library. Using the National Institutes of Health (NIH) RePORTER, forty-four researchers were identified and later contacted through individualized emails. Nine researchers responded to the email followed by six in-person or phone discussions. At the conclusion of this process, two researchers submitted applications for supplemental funding, and both of these applications were successful. This method confirmed these users could benefit from the skills and knowledge of health sciences librarians, but they are largely unaware of this.
LEAP into the Pfizer Global Virtual Library (PGVL) space: creation of readily synthesizable design ideas automatically.

Science.gov (United States)

Hu, Qiyue; Peng, Zhengwei; Kostrowicki, Jaroslav; Kuki, Atsuo

2011-01-01

Pfizer Global Virtual Library (PGVL) of 10(13) readily synthesizable molecules offers a tremendous opportunity for lead optimization and scaffold hopping in drug discovery projects. However, mining into a chemical space of this size presents a challenge for the concomitant design informatics due to the fact that standard molecular similarity searches against a collection of explicit molecules cannot be utilized, since no chemical information system could create and manage more than 10(8) explicit molecules. Nevertheless, by accepting a tolerable level of false negatives in search results, we were able to bypass the need for full 10(13) enumeration and enabled the efficient similarity search and retrieval into this huge chemical space for practical usage by medicinal chemists. In this report, two search methods (LEAP1 and LEAP2) are presented. The first method uses PGVL reaction knowledge to disassemble the incoming search query molecule into a set of reactants and then uses reactant-level similarities into actual available starting materials to focus on a much smaller sub-region of the full virtual library compound space. This sub-region is then explicitly enumerated and searched via a standard similarity method using the original query molecule. The second method uses a fuzzy mapping onto candidate reactions and does not require exact disassembly of the incoming query molecule. Instead Basis Products (or capped reactants) are mapped into the query molecule and the resultant asymmetric similarity scores are used to prioritize the corresponding reactions and reactant sets. All sets of Basis Products are inherently indexed to specific reactions and specific starting materials. This again allows focusing on a much smaller sub-region for explicit enumeration and subsequent standard product-level similarity search. A set of validation studies were conducted. The results have shown that the level of false negatives for the disassembly-based method is acceptable when the
Effects of a random noisy oracle on search algorithm complexity

International Nuclear Information System (INIS)

Shenvi, Neil; Brown, Kenneth R.; Whaley, K. Birgitta

2003-01-01

Grover's algorithm provides a quadratic speed-up over classical algorithms for unstructured database or library searches. This paper examines the robustness of Grover's search algorithm to a random phase error in the oracle and analyzes the complexity of the search process as a function of the scaling of the oracle error with database or library size. Both the discrete- and continuous-time implementations of the search algorithm are investigated. It is shown that unless the oracle phase error scales as O(N -1/4 ), neither the discrete- nor the continuous-time implementation of Grover's algorithm is scalably robust to this error in the absence of error correction
E-library Implementation in Library University of Riau

Science.gov (United States)

Yuhelmi; Rismayeti

2017-12-01

This research aims to see how the e-book implementation in Library University of Riau and the obstacle in its implementation. In the Globalization era, digital libraries should be developed or else it will decrease the readers’ interest, with the recent advanced technology, digital libraries are one of the learning tools that can be used to finding an information through the internet access, hence digital libraries or commonly known as E-Library is really helping the students and academic community in finding information. The methods that used in this research is Observation, Interview, and Literature Study. The respondents in this research are the staff who involved in the process of digitization in Library University of Riau. The result of this research shows that implementation of e-library in Library University of Riau is already filled the user needs for now, although there is obstacle faced just like technical problems for example the internet connection speed and the technical problem to convert the format from Microsoft Word .doc to Adobe.pdf
The AXES-lite video search engine

NARCIS (Netherlands)

Chen, Shu; McGuinness, Kevin; Aly, Robin; de Jong, Franciska M.G.; O' Connor, Noel E.

The aim of AXES is to develop tools that provide various types of users with new engaging ways to interact with audiovisual libraries, helping them discover, browse, navigate, search, and enrich archives. This paper describes the initial (lite) version of the AXES search engine, which is targeted at
Identification of toxic cyclopeptides based on mass spectral library matching

Directory of Open Access Journals (Sweden)

Boris L. Milman

2014-08-01

Full Text Available To gain perspective on the use of tandem mass spectral libraries for identification of toxic cyclic peptides, the new library was built from 263 mass spectra (mainly MS2 spectra of 59 compounds of that group, such as microcystins, amatoxins, and some related compounds. Mass spectra were extracted from the literature or specially acquired on ESI-Q-ToF and MALDI-ToF/ToF tandem instruments. ESI-MS2 product-ion mass spectra appeared to be rather close to MALDI-ToF/ToF fragment spectra which are uncommon for mass spectral libraries. Testing of the library was based on searches where reference spectra were in turn cross-compared. The percentage of 1st rank correct identifications (true positives was 70% in a general case and 88–91% without including knowingly defective (‘one-dimension’ spectra as test ones. The percentage of 88–91% is the principal estimate for the overall performance of this library that can be used in a method of choice for identification of individual cyclopeptides and also for group recognition of individual classes of such peptides. The approach to identification of cyclopeptides based on mass spectral library matching proved to be the most effective for abundant toxins. That was confirmed by analysis of extracts from two cyanobacterial strains.
Iterative optimization of performance libraries by hierarchical division of codes

International Nuclear Information System (INIS)

Donadio, S.

2007-09-01

The increasing complexity of hardware features incorporated in modern processors makes high performance code generation very challenging. Library generators such as ATLAS, FFTW and SPIRAL overcome this issue by empirically searching in the space of possible program versions for the one that performs the best. This thesis explores fully automatic solution to adapt a compute-intensive application to the target architecture. By mimicking complex sequences of transformations useful to optimize real codes, we show that generative programming is a practical tool to implement a new hierarchical compilation approach for the generation of high performance code relying on the use of state-of-the-art compilers. As opposed to ATLAS, this approach is not application-dependant but can be applied to fairly generic loop structures. Our approach relies on the decomposition of the original loop nest into simpler kernels. These kernels are much simpler to optimize and furthermore, using such codes makes the performance trade off problem much simpler to express and to solve. Finally, we propose a new approach for the generation of performance libraries based on this decomposition method. We show that our method generates high-performance libraries, in particular for BLAS. (author)
Multicultural E-Resources: An Exploratory Study of Resources Held by ARL Libraries

Science.gov (United States)

Maxey-Harris, Charlene

2010-01-01

The purpose of this study was to discover what libraries belonging to the Association of Research Libraries are subscribing to in support of multicultural and diversity research. A list of bibliographic and digital collections was created and searched for in the online public access catalogs of academic and research libraries in 2005 and 2008. A…
Method of Improving Personal Name Search in Academic Information Service

Directory of Open Access Journals (Sweden)

Heejun Han

2012-12-01

Full Text Available All academic information on the web or elsewhere has its creator, that is, a subject who has created the information. The subject can be an individual, a group, or an institution, and can be a nation depending on the nature of the relevant information. Most information is composed of a title, an author, and contents. An essay which is under the academic information category has metadata including a title, an author, keyword, abstract, data about publication, place of publication, ISSN, and the like. A patent has metadata including the title, an applicant, an inventor, an attorney, IPC, number of application, and claims of the invention. Most web-based academic information services enable users to search the information by processing the meta-information. An important element is to search information by using the author field which corresponds to a personal name. This study suggests a method of efficient indexing and using the adjacent operation result ranking algorithm to which phrase search-based boosting elements are applied, and thus improving the accuracy of the search results of personal names. It also describes a method for providing the results of searching co-authors and related researchers in searching personal names. This method can be effectively applied to providing accurate and additional search results in the academic information services.
Innovative public library services - staff-less or staff-intensive?

DEFF Research Database (Denmark)

Johannsen, Carl Gustav Viggo

2014-01-01

Purpose – Several recent library innovations seem to make professional and clerical staff superfluous such as automated loan and delivery equipment, staff-less libraries open in 80 hours a week, and virtual services, enabling users to search the library catalogue and make reservations of library...... materials from their home address. The purpose of this paper is to examine whether such developments will necessarily lead to a situation where public libraries become self-service institutions or to what extent self-service and innovative staff-intensive library services can develop and co......-exist. Furthermore, the paper will examine what challenges library leaders face and what they can do, and actually have done, to handle staff resistance and other related problems to the benefit of both the users, the local communities, and also, the staff, in particular, when introducing new and innovative services...
Modular high-throughput test stand for versatile screening of thin-film materials libraries

International Nuclear Information System (INIS)

Thienhaus, Sigurd; Hamann, Sven; Ludwig, Alfred

2011-01-01

Versatile high-throughput characterization tools are required for the development of new materials using combinatorial techniques. Here, we describe a modular, high-throughput test stand for the screening of thin-film materials libraries, which can carry out automated electrical, magnetic and magnetoresistance measurements in the temperature range of −40 to 300 °C. As a proof of concept, we measured the temperature-dependent resistance of Fe–Pd–Mn ferromagnetic shape-memory alloy materials libraries, revealing reversible martensitic transformations and the associated transformation temperatures. Magneto-optical screening measurements of a materials library identify ferromagnetic samples, whereas resistivity maps support the discovery of new phases. A distance sensor in the same setup allows stress measurements in materials libraries deposited on cantilever arrays. A combination of these methods offers a fast and reliable high-throughput characterization technology for searching for new materials. Using this approach, a composition region has been identified in the Fe–Pd–Mn system that combines ferromagnetism and martensitic transformation.

The Presence of Web 2.0 Applications Is Associated with the Overall Service Quality of Library Websites. A Review of: Chua, A. Y. K., & Goh, D. H. (2010. A study of Web 2.0 applications in library websites. Library & Information Science Research, 32(3, 203-211.

Directory of Open Access Journals (Sweden)

Leslie Bussert

2011-03-01

Full Text Available Objective – To determine the prevalence and use of web 2.0 applications in library websites and to determine whether or not their presence enhances the quality of the sites.Design – Content analysis.Setting – Public and academic libraries in North America, Europe, and Asia.Subjects – A total of 120 academic and public library websites in English.Methods – This study identified and selected library websites from academic and public libraries using a combination of directories, ratings reports, and ranking lists from three geographic regions. Over a four-month period in 2009, three coders conducted a three-step content analysis of the selected library websites. This analysis was conducted after having established inter-coder reliability using Cohen’s Kappa and analytic procedure familiarity, using a randomly selected pilot set of 30 library websites. The remaining 90 websites were evenly distributed among the three coders for analysis. They determined whether web 2.0 applications were present, examined how those applications were used, and gave an overall appraisal of website quality. Coders inspected library website links, conducted site searches, used search engines, and searched within major social networking sites to determine the presence of web 2.0 applications. A quality framework classification scheme was used during coding to identify how the web 2.0 applications were being used within library websites. This framework was established around four dimensions of library services: information acquisition (blogs and wikis, information dissemination (Rich Site Summary, or “RSS”, information organization (social tagging, and information sharing (social networking and instant messaging. A five-point Likert scale was also used in concert with a website quality evaluation framework to assess the quality of the library websites. This framework included three aspects of website quality: system quality, information quality, and service
Forensic examination of ink by high-performance thin layer chromatography--the United States Secret Service Digital Ink Library.

Science.gov (United States)

Neumann, Cedric; Ramotowski, Robert; Genessay, Thibault

2011-05-13

Forensic examinations of ink have been performed since the beginning of the 20th century. Since the 1960s, the International Ink Library, maintained by the United States Secret Service, has supported those analyses. Until 2009, the search and identification of inks were essentially performed manually. This paper describes the results of a project designed to improve ink samples' analytical and search processes. The project focused on the development of improved standardization procedures to ensure the best possible reproducibility between analyses run on different HPTLC plates. The successful implementation of this new calibration method enabled the development of mathematical algorithms and of a software package to complement the existing ink library. Copyright © 2010 Elsevier B.V. All rights reserved.
A method to incorporate interstitial components into the TPS gynecologic rigid applicator library

Directory of Open Access Journals (Sweden)

Antonio Otal

2017-01-01

Full Text Available Purpose: T2 magnetic resonance imaging (MRI is recommended as the imaging modality for image-guided brachytherapy. In locally advanced cervical carcinoma, combined endocavitary and interstitial applicators are appropriate (Vienna or Utrecht. To cover extensive disease, Template Benidorm (TB was developed. Treatment planning system applicator libraries are currently unavailable for the Utrecht applicator or the TB. The purpose of this work is to develop an applicator library for both applicators. Material and methods: The library developed in this work has been used in the Oncentra Brachytherapy TPS, version 4.3.0, which has a brachytherapy module that includes a library of rigid applicators. To add the needles of the Utrecht applicator and to model the TB, we used FreeCAD and MeshLab. The reconstruction process was based on the points that the rigid section and the interstitial part have in common. This, together with the free length, allowed us to ascertain the position of the tip. Results: In case of the Utrecht applicator, one of the sources of uncertainty in the reconstruction was determining the distance of the tip of needle from the ovoid. In case of the TB, the large number of needles involved made their identification time consuming. The developed library resolved both issues. Conclusions : The developed library for the Utrecht and TB is feasible and efficient improving accuracy. It allows all the required treatment planning to proceed using just a T2 MRI sequence. The additional use of specific free available software applications makes it possible to add this information to the already existing library of the Oncentra Brachytherapy TPS. Specific details not included on this manuscript will be available under request. This library is also currently being implemented also into the Sagiplan v 2.0 TPS.
Searching for Suicide Methods: Accessibility of Information About Helium as a Method of Suicide on the Internet.

Science.gov (United States)

Gunnell, David; Derges, Jane; Chang, Shu-Sen; Biddle, Lucy

2015-01-01

Helium gas suicides have increased in England and Wales; easy-to-access descriptions of this method on the Internet may have contributed to this rise. To investigate the availability of information on using helium as a method of suicide and trends in searching about this method on the Internet. We analyzed trends in (a) Google searching (2004-2014) and (b) hits on a Wikipedia article describing helium as a method of suicide (2013-2014). We also investigated the extent to which helium was described as a method of suicide on web pages and discussion forums identified via Google. We found no evidence of rises in Internet searching about suicide using helium. News stories about helium suicides were associated with increased search activity. The Wikipedia article may have been temporarily altered to increase awareness of suicide using helium around the time of a celebrity suicide. Approximately one third of the links retrieved using Google searches for suicide methods mentioned helium. Information about helium as a suicide method is readily available on the Internet; the Wikipedia article describing its use was highly accessed following celebrity suicides. Availability of online information about this method may contribute to rises in helium suicides.
The persistence of error: a study of retracted articles on the Internet and in personal libraries.

Science.gov (United States)

Davis, Philip M

2012-07-01

To determine the accessibility of retracted articles residing on non-publisher websites and in personal libraries. Searches were performed to locate Internet copies of 1,779 retracted articles identified in MEDLINE, published between 1973 and 2010, excluding the publishers' website. Found copies were classified by article version and location. Mendeley (a bibliographic software) was searched for copies residing in personal libraries. Non-publisher websites provided 321 publicly accessible copies for 289 retracted articles: 304 (95%) copies were the publisher' versions, and 13 (4%) were final manuscripts. PubMed Central had 138 (43%) copies; educational websites 94 (29%); commercial websites 24 (7%); advocacy websites 16 (5%); and institutional repositories 10 (3%). Just 16 [corrected] (5%) full-article views included a retraction statement. Personal Mendeley libraries contained records for 1,340 (75%) retracted articles, shared by 3.4 users, on average. The benefits of decentralized access to scientific articles may come with the cost of promoting incorrect, invalid, or untrustworthy science. Automated methods to deliver status updates to readers may reduce the persistence of error in the scientific literature.
CITE NLM: Natural-Language Searching in an Online Catalog.

Science.gov (United States)

Doszkocs, Tamas E.

1983-01-01

The National Library of Medicine's Current Information Transfer in English public access online catalog offers unique subject search capabilities--natural-language query input, automatic medical subject headings display, closest match search strategy, ranked document output, dynamic end user feedback for search refinement. References, description…
Lyceum: A Multi-Protocol Digital Library Gateway

Science.gov (United States)

Maa, Ming-Hokng; Nelson, Michael L.; Esler, Sandra L.

1997-01-01

Lyceum is a prototype scalable query gateway that provides a logically central interface to multi-protocol and physically distributed, digital libraries of scientific and technical information. Lyceum processes queries to multiple syntactically distinct search engines used by various distributed information servers from a single logically central interface without modification of the remote search engines. A working prototype (http://www.larc.nasa.gov/lyceum/) demonstrates the capabilities, potentials, and advantages of this type of meta-search engine by providing access to over 50 servers covering over 20 disciplines.
Millennial Undergraduate Research Strategies in Web and Library Information Retrieval Systems

Science.gov (United States)

Porter, Brandi

2011-01-01

This article summarizes the author's dissertation regarding search strategies of millennial undergraduate students in Web and library online information retrieval systems. Millennials bring a unique set of search characteristics and strategies to their research since they have never known a world without the Web. Through the use of search engines,…
ABCD, an Open Source Software for Modern Libraries

Directory of Open Access Journals (Sweden)

Sangeeta Namdev Dhamdhere

2011-12-01

Full Text Available Nowadays, librarians are using various kinds of open source software for different purposes such as library automation, digitization, institutional repository, content management. ABCD, acronym for Automatisación de Bibliotécas y Centros de Documentación, is one of such software. It caters to almost all present needs of modern libraries of any sizes. It offers a solution to library automation with ISBD as well as local formats. It has excellent indexing and retrieval features based on UNESCO’s ISIS technology, a web OPAC, and a library Portal with integrated meta-search and content management system to manage online as well as offline digital resources and physical documents and media.
Aplikasi Search Engine Perpustakaan Petra Berbasis Android dengan Apache SOLR

Directory of Open Access Journals (Sweden)

Andreas Handojo

2016-07-01

Full Text Available Abstrak: Pendidikan merupakan kebutuhan yang penting bagi manusia untuk meningkatkan kemampuan serta taraf hidupnya.Selain melalui pendidikan formal, ilmu juga dapat diperoleh melalui media cetak atau buku.Perpustakaan merupakan salah satu sarana yang penting dalam menunjang hal tersebut.Meskipun sangat bermanfaat, terdapat kesulitan penggunaan layanan perpustakaan, karena terlalu banyaknya koleksi pustaka yang ada (buku, jurnal, majalah, dan sebagainya sehingga sulit untuk menemukan buku yang ingin dicari.Oleh sebab itu, selain harus berkembang dengan penyediaan koleksi pustaka, perpustakaan harus dapat mengikuti perkembangan zaman yang ada sehingga mempermudah penggunaan layanan perpustakaan.Saat iniperpustakaan Universitas Kristen Petra memiliki perpustakaan dengan kurang lebih 230.000 koleksi fisik maupun digital (berdasarkan data 2014.Dimana daftar koleksi fisik dan dokumen digital dapat diakses melalui website perpustakaan.Adanya koleksi pustaka yang sangat banyak ini menyebabkan kesulitan pengguna dalam melakukan proses pencarian. Sehingga guna menambah fitur layanan yang diberikan maka pada penelitian ini dibuatlah sebuah aplikasi layanan search engine perpustakaan menggunakan platform Apache SOLR dan database PostgreSQL. Selain itu, guna lebih meningkatkan kemudahan akses maka aplikasi ini dibuat dengan menggunakan platform mobile device berbasis Android.Selain pengujian terhadap aplikasi dilakukan juga pengujian dengan mengedarkan kuesioner terhadap 50 calon pengguna.Dari hasil kuestioner tersebut menunjukkan bahwa fitur-fitur yang dibuat telah sesuai dengan kebutuhan pengguna (78%. Kata kunci: SOLR, Mesin Pencarian, Perpustakaan, PostgreSQL Abstract: Education is an essential requirement for people to improve their standard of living. Other than through formal education, science can also be obtained through the print media or books. Library is one important tool supporting it. Although it is useful, there are difficulties use library
Assessment and Comparison of Search capabilities of Web-based Meta-Search Engines: A Checklist Approach

Directory of Open Access Journals (Sweden)

Alireza Isfandiyari Moghadam

2010-03-01

Full Text Available The present investigation concerns evaluation, comparison and analysis of search options existing within web-based meta-search engines. 64 meta-search engines were identified. 19 meta-search engines that were free, accessible and compatible with the objectives of the present study were selected. An author’s constructed check list was used for data collection. Findings indicated that all meta-search engines studied used the AND operator, phrase search, number of results displayed setting, previous search query storage and help tutorials. Nevertheless, none of them demonstrated any search options for hypertext searching and displaying the size of the pages searched. 94.7% support features such as truncation, keywords in title and URL search and text summary display. The checklist used in the study could serve as a model for investigating search options in search engines, digital libraries and other internet search tools.
Evidence-based librarianship: searching for the needed EBL evidence.

Science.gov (United States)

Eldredge, J D

2000-01-01

This paper discusses the challenges of finding evidence needed to implement Evidence-Based Librarianship (EBL). Focusing first on database coverage for three health sciences librarianship journals, the article examines the information contents of different databases. Strategies are needed to search for relevant evidence in the library literature via these databases, and the problems associated with searching the grey literature of librarianship. Database coverage, plausible search strategies, and the grey literature of library science all pose challenges to finding the needed research evidence for practicing EBL. Health sciences librarians need to ensure that systems are designed that can track and provide access to needed research evidence to support Evidence-Based Librarianship (EBL).
Job Search as Goal-Directed Behavior: Objectives and Methods

Science.gov (United States)

Van Hoye, Greet; Saks, Alan M.

2008-01-01

This study investigated the relationship between job search objectives (finding a new job/turnover, staying aware of job alternatives, developing a professional network, and obtaining leverage against an employer) and job search methods (looking at job ads, visiting job sites, networking, contacting employment agencies, contacting employers, and…
Library design practices for success in lead generation with small molecule libraries.

Science.gov (United States)

Goodnow, R A; Guba, W; Haap, W

2003-11-01

The generation of novel structures amenable to rapid and efficient lead optimization comprises an emerging strategy for success in modern drug discovery. Small molecule libraries of sufficient size and diversity to increase the chances of discovery of novel structures make the high throughput synthesis approach the method of choice for lead generation. Despite an industry trend for smaller, more focused libraries, the need to generate novel lead structures makes larger libraries a necessary strategy. For libraries of a several thousand or more members, solid phase synthesis approaches are the most suitable. While the technology and chemistry necessary for small molecule library synthesis continue to advance, success in lead generation requires rigorous consideration in the library design process to ensure the synthesis of molecules possessing the proper characteristics for subsequent lead optimization. Without proper selection of library templates and building blocks, solid phase synthesis methods often generate molecules which are too heavy, too lipophilic and too complex to be useful for lead optimization. The appropriate filtering of virtual library designs with multiple computational tools allows the generation of information-rich libraries within a drug-like molecular property space. An understanding of the hit-to-lead process provides a practical guide to molecular design characteristics. Examples of leads generated from library approaches also provide a benchmarking of successes as well as aspects for continued development of library design practices.
Eye tracking in Library and Information Science

DEFF Research Database (Denmark)

Lund, Haakon

2016-01-01

Purpose The purpose of this paper is to present a systematic literature review of the application of eye-tracking technology within the field of library and information science. Eye-tracking technology has now reached a level of maturity, which makes the use of the technology more accessible....... Subsequently, a growing interest in employing eye tracking as a methodology within library and information science research must be anticipated. Design/methodology/approach The review follows the guidelines set in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses recommendations. Two...... reference databases are searched for relevant references: Library and Information Science Abstracts and Library, Information Science and Technology Abstracts. The main selection criteria are peer-reviewed literature that describes the experimental setting, including which eye-tracking equipment was used...
Optimizing use of library technology.

Science.gov (United States)

Wink, Diane M; Killingsworth, Elizabeth K

2011-01-01

In this bimonthly series, the author examines how nurse educators can use the Internet and Web-based computer technologies such as search, communication, collaborative writing tools; social networking and social bookmarking sites; virtual worlds; and Web-based teaching and learning programs. This article describes optimizing the use of library technology.
The Imperative Of Literature Search For Research In Nigeria | Madu ...

African Journals Online (AJOL)

The paper while advancing reasons for literature search described how the library can assist in literature search. It finally discussed the various approaches and levels of search especially on the web and the problems researchers are most likely to encounter. Keywords: Research, Literature Search, Nigeria. The Information ...
Undergraduate Students with Strong Tendencies Towards Critical Thinking Experience Less Library Anxiety. A Review of: Kwon, Nahyun. “A Mixed‐Methods Investigation of the Relationship between Critical Thinking and Library Anxiety among Undergraduate Students in their Information Search Process.” College & Research Libraries 69.2 (2008: 117‐31.

Directory of Open Access Journals (Sweden)

Cari Merkley

2009-12-01

Full Text Available Objective – To investigate the nature of the association between a student’s critical thinking disposition and the extent to which they suffer from library anxiety.Design – Standardized quantitative survey instruments and a qualitative content analysis of student essays.Setting – A state (publically funded research university located in the southeast United States.Subjects – 137 undergraduate students enrolled in the Library and Research Skills course.Methods – Undergraduate students enrolled in the three‐credit course Library and Research Skills during the spring 2006 semester were invited to participate in the study. Of 180 students registered in the course, 137 volunteered to take part. Data collection took place in the first two weeks of the semester. Participants were asked to complete two standardized survey instruments: the California Critical Thinking Disposition Inventory (CCTDI and the Library Anxiety Scale (LAS. The purpose of the CCTDI is to “measure a person’s disposition to use critical thinking” (119. The instrument consists of seven scales: “truth‐seeking”; “open-mindedness”; “analyticity”; “systematicity”; “critical thinking self‐confidence”; “inquisitiveness”; and “maturity” (119. “Truth‐seeking” is a commitment to seeking answers even if the process proves difficult or reveals information outside of one’s belief system, “systematicity” is defined as an organized approach to problem solving, and “maturity” is the ability to make “reflective decisions when facing ill‐structured problem situations” (119. “Analyticity” refers to a subject’s ability to anticipate possible outcomes, “open‐mindedness” to being open to different points of view, “critical thinking self‐ confidence” to a belief in one’s own critical thinking skills, and “inquisitiveness” to “intellectual curiosity” (119. Participants scored 75 items using a six�
Libraries Today, Libraries Tomorrow: Contemporary Library Practices and the Role of Library Space in the L

Directory of Open Access Journals (Sweden)

Ana Vogrinčič Čepič

2013-09-01

Full Text Available ABSTRACTPurpose: The article uses sociological concepts in order to rethink the changes in library practices. Contemporary trends are discussed with regard to the changing nature of working habits, referring mostly to the new technology, and the (emergence of the third space phenomenon. The author does not regard libraries only as concrete public service institutions, but rather as complex cultural forms, taking in consideration wider social context with a stress on users’ practices in relation to space.Methodology/approach: The article is based on the (self- observation of the public library use, and on the (discourse analysis of internal library documents (i.e. annual reports and plans and secondary sociological literature. As such, the cultural form approach represents a classic method of sociology of culture.Results: The study of relevant material in combination with direct personal experiences reveals socio-structural causes for the change of users’ needs and habits, and points at the difficulty of spatial redefinition of libraries as well as at the power of the discourse.Research limitations: The article is limited to an observation of users’ practices in some of the public libraries in Ljubljana and examines only a small number of annual reports – the discoveries are then further debated from the sociological perspective.Originality/practical implications: The article offers sociological insight in the current issues of the library science and tries to suggest a wider explanation that could answer some of the challenges of the contemporary librarianship.
Evaluation of a new method for librarian-mediated literature searches for systematic reviews

NARCIS (Netherlands)

W.M. Bramer (Wichor); Rethlefsen, M.L. (Melissa L.); F. Mast (Frans); J. Kleijnen (Jos)

2017-01-01

textabstractObjective: To evaluate and validate the time of completion and results of a new method of searching for systematic reviews, the exhaustive search method (ESM), using a pragmatic comparison. Methods: Single-line search strategies were prepared in a text document. Term completeness was

Comparative analysis of machine learning methods in ligand-based virtual screening of large compound libraries.

Science.gov (United States)

Ma, Xiao H; Jia, Jia; Zhu, Feng; Xue, Ying; Li, Ze R; Chen, Yu Z

2009-05-01

Machine learning methods have been explored as ligand-based virtual screening tools for facilitating drug lead discovery. These methods predict compounds of specific pharmacodynamic, pharmacokinetic or toxicological properties based on their structure-derived structural and physicochemical properties. Increasing attention has been directed at these methods because of their capability in predicting compounds of diverse structures and complex structure-activity relationships without requiring the knowledge of target 3D structure. This article reviews current progresses in using machine learning methods for virtual screening of pharmacodynamically active compounds from large compound libraries, and analyzes and compares the reported performances of machine learning tools with those of structure-based and other ligand-based (such as pharmacophore and clustering) virtual screening methods. The feasibility to improve the performance of machine learning methods in screening large libraries is discussed.
Case study: the health SmartLibrary experiences in web personalization and customization at the Galter health sciences library, Northwestern University.

Science.gov (United States)

Shedlock, James; Frisque, Michelle; Hunt, Steve; Walton, Linda; Handler, Jonathan; Gillam, Michael

2010-04-01

How can the user's access to health information, especially full-text articles, be improved? The solution is building and evaluating the Health SmartLibrary (HSL). The setting is the Galter Health Sciences Library, Feinberg School of Medicine, Northwestern University. The HSL was built on web-based personalization and customization tools: My E-Resources, Stay Current, Quick Search, and File Cabinet. Personalization and customization data were tracked to show user activity with these value-added, online services. Registration data indicated that users were receptive to personalized resource selection and that the automated application of specialty-based, personalized HSLs was more frequently adopted than manual customization by users. Those who did customize customized My E-Resources and Stay Current more often than Quick Search and File Cabinet. Most of those who customized did so only once. Users did not always take advantage of the services designed to aid their library research experiences. When personalization is available at registration, users readily accepted it. Customization tools were used less frequently; however, more research is needed to determine why this was the case.
Bayesian methods in the search for MH370

CERN Document Server

Davey, Sam; Holland, Ian; Rutten, Mark; Williams, Jason

2016-01-01

This book demonstrates how nonlinear/non-Gaussian Bayesian time series estimation methods were used to produce a probability distribution of potential MH370 flight paths. It provides details of how the probabilistic models of aircraft flight dynamics, satellite communication system measurements, environmental effects and radar data were constructed and calibrated. The probability distribution was used to define the search zone in the southern Indian Ocean. The book describes particle-filter based numerical calculation of the aircraft flight-path probability distribution and validates the method using data from several of the involved aircraft’s previous flights. Finally it is shown how the Reunion Island flaperon debris find affects the search probability distribution.
Searching Fragment Spaces with feature trees.

Science.gov (United States)

Lessel, Uta; Wellenzohn, Bernd; Lilienthal, Markus; Claussen, Holger

2009-02-01

Virtual combinatorial chemistry easily produces billions of compounds, for which conventional virtual screening cannot be performed even with the fastest methods available. An efficient solution for such a scenario is the generation of Fragment Spaces, which encode huge numbers of virtual compounds by their fragments/reagents and rules of how to combine them. Similarity-based searches can be performed in such spaces without ever fully enumerating all virtual products. Here we describe the generation of a huge Fragment Space encoding about 5 * 10(11) compounds based on established in-house synthesis protocols for combinatorial libraries, i.e., we encode practically evaluated combinatorial chemistry protocols in a machine readable form, rendering them accessible to in silico search methods. We show how such searches in this Fragment Space can be integrated as a first step in an overall workflow. It reduces the extremely huge number of virtual products by several orders of magnitude so that the resulting list of molecules becomes more manageable for further more elaborated and time-consuming analysis steps. Results of a case study are presented and discussed, which lead to some general conclusions for an efficient expansion of the chemical space to be screened in pharmaceutical companies.
Internet Use for Service Provision and Research in Libraries and ...

African Journals Online (AJOL)

This study discussed internet, the services and the uses, it can be put to in the provision of library services, or in an information centre. Literature search was used to elicit information for this study. The results revealed that whenever internet intervenes in library operations, these is bridge in time, space, minimized cost and ...
Lagos Journal of Library and Information Science: Advanced Search

African Journals Online (AJOL)

Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...
Overview of the INEX 2014 Social Book Search Track

DEFF Research Database (Denmark)

Koolen, Marijn; Bogers, Toine; Kazai, Gabriella

2014-01-01

The goal of the INEX 2014 Social Book Search Track is to evaluate approaches for supporting users in searching collections of books based on book metadata and associated user-generated content. The track investigates the complex nature of relevance in book search and the role of traditional...... and user-generated book metadata in retrieval. We extended last year’s investigation into the nature of book suggestions from the LibraryThing forums and how they compare to book relevance judgements. Participants were encouraged to incorporate rich user profiles of both topic creators and other Library......Thing users to explore the relative value of recommendation and retrieval paradigms for book search. We found further support that such suggestions are a valuable alternative to traditional test collections that are based on top-k pooling and editorial relevance judgements....
Distributed Cooperative Search Control Method of Multiple UAVs for Moving Target

Directory of Open Access Journals (Sweden)

Chang-jian Ru

2015-01-01

Full Text Available To reduce the impact of uncertainties caused by unknown motion parameters on searching plan of moving targets and improve the efficiency of UAV’s searching, a novel distributed Multi-UAVs cooperative search control method for moving target is proposed in this paper. Based on detection results of onboard sensors, target probability map is updated using Bayesian theory. A Gaussian distribution of target transition probability density function is introduced to calculate prediction probability of moving target existence, and then target probability map can be further updated in real-time. A performance index function combining with target cost, environment cost, and cooperative cost is constructed, and the cooperative searching problem can be transformed into a central optimization problem. To improve computational efficiency, the distributed model predictive control method is presented, and thus the control command of each UAV can be obtained. The simulation results have verified that the proposed method can avoid the blindness of UAV searching better and improve overall efficiency of the team effectively.
Charging Users for Library Service.

Science.gov (United States)

Cooper, Michael D.

1978-01-01

Examines the question of instituting direct charges for library service, using on-line bibliographic searching as an example, and contrasts this with the current indirect charging system where services are paid for by taxes. Information, as a merit good, should be supplied with or without direct charges, depending upon user status. (CWM)
Quantification of massively parallel sequencing libraries - a comparative study of eight methods

DEFF Research Database (Denmark)

Hussing, Christian; Kampmann, Marie-Louise; Mogensen, Helle Smidt

2018-01-01

Quantification of massively parallel sequencing libraries is important for acquisition of monoclonal beads or clusters prior to clonal amplification and to avoid large variations in library coverage when multiple samples are included in one sequencing analysis. No gold standard for quantification...... estimates followed by Qubit and electrophoresis-based instruments (Bioanalyzer, TapeStation, GX Touch, and Fragment Analyzer), while SYBR Green and TaqMan based qPCR assays gave the lowest estimates. qPCR gave more accurate predictions of sequencing coverage than Qubit and TapeStation did. Costs, time......-consumption, workflow simplicity, and ability to quantify multiple samples are discussed. Technical specifications, advantages, and disadvantages of the various methods are pointed out....
mySearch changed my life – a resource discovery journey

OpenAIRE

Crowley, Emma J.

2013-01-01

mySearch: the federated years mySearch: choosing a new platform mySearch: EBSCO Discovery Service (EDS) Implementing a new system Technical challenges Has resource discovery enhanced experiences at BU? Ongoing challenges Implications for library management systems Implications for information literacy Questions
Systematic hybrid LOH: a new method to reduce false positives and negatives during screening of yeast gene deletion libraries

DEFF Research Database (Denmark)

Alvaro, D.; Sunjevaric, I.; Reid, R. J.

2006-01-01

We have developed a new method, systematic hybrid loss of heterozygosity, to facilitate genomic screens utilizing the yeast gene deletion library. Screening is performed using hybrid diploid strains produced through mating the library haploids with strains from a different genetic background......, to minimize the contribution of unpredicted recessive genetic factors present in the individual library strains. We utilize a set of strains where each contains a conditional centromere construct on one of the 16 yeast chromosomes that allows the destabilization and selectable loss of that chromosome. After...... complementation of any spurious recessive mutations in the library strain, facilitating attribution of the observed phenotype to the documented gene deletion and dramatically reducing false positive results commonly obtained in library screens. The systematic hybrid LOH method can be applied to virtually any...
cDNA library Table - KAIKOcDNA | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available c00951-005 Description of data contents List of Bombyx mori cDNA libraries. Data file File name: kaiko_cdna_...library.zip File URL: ftp://ftp.biosciencedbc.jp/archive/kaiko-cdna/LATEST/kaiko_cdna_library.zip File size:... 4.8 KB Simple search URL http://togodb.biosciencedbc.jp/togodb/view/kaiko_cdna_l
Teaching Electronic Literacy A Concepts-Based Approach for School Library Media Specialists

CERN Document Server

Craver, Kathleen W

1997-01-01

School library media specialists will find this concepts-based approach to teaching electronic literacy an indispensable basic tool for instructing students and teachers. It provides step-by-step instruction on how to find and evaluate needed information from electronic databases and the Internet, how to formulate successful electronic search strategies and retrieve relevant results, and how to interpret and critically analyze search results. The chapters contain a suggested lesson plan and sample assignments for the school library media specialist to use in teaching electronic literacy skills
ICT skills of library personnel in a changing digital library environment

African Journals Online (AJOL)

The survey examined ICT skills of library personnel working in academic libraries in Oyo state vis –a- vis level of competence and methods of acquisition. It also considered whether the personnel's ICT skills competence is related to their method of ICT skills acquisition. The sample used consists of 155 professional and ...
Remarks on search methods for stable, massive, elementary particles

International Nuclear Information System (INIS)

Perl, Martin L.

2001-01-01

This paper was presented at the 69th birthday celebration of Professor Eugene Commins, honoring his research achievements. These remarks are about the experimental techniques used in the search for new stable, massive particles, particles at least as massive as the electron. A variety of experimental methods such as accelerator experiments, cosmic ray studies, searches for halo particles in the galaxy and searches for exotic particles in bulk matter are described. A summary is presented of the measured limits on the existence of new stable, massive particle
Factors Influencing Virtual Patron Satisfaction with Online Library Resources and Services

Science.gov (United States)

Tyler, Katherine; Hastings, Nancy B.

2011-01-01

College students are accessing virtual libraries whether they are on campus or learning from a distance. Academic institutions serving virtual patrons must remain focused on meeting the needs of those library users by continually examining their preferences, their searching behavior, and the information they seek. The purpose of this research was…
Exploration of Stellarator Configuration Space with Global Search Methods

International Nuclear Information System (INIS)

Mynick, H.E.; Pomphrey, N.; Ethier, S.

2001-01-01

An exploration of stellarator configuration space z for quasi-axisymmetric stellarator (QAS) designs is discussed, using methods which provide a more global view of that space. To this end, we have implemented a ''differential evolution'' (DE) search algorithm in an existing stellarator optimizer, which is much less prone to become trapped in local, suboptimal minima of the cost function chi than the local search methods used previously. This search algorithm is complemented by mapping studies of chi over z aimed at gaining insight into the results of the automated searches. We find that a wide range of the attractive QAS configurations previously found fall into a small number of classes, with each class corresponding to a basin of chi(z). We develop maps on which these earlier stellarators can be placed, the relations among them seen, and understanding gained into the physics differences between them. It is also found that, while still large, the region of z space containing practically realizable QAS configurations is much smaller than earlier supposed
CSIR's new integrated electronic library information-system

CSIR Research Space (South Africa)

Michie, A

1995-08-01

Full Text Available The CSIR has developed a CDROM-based electronic library information system which provides the ability to reproduce and search for published information and colour brochures on the computer screen. The system integrates this information with online...
Evaluation of library preparation methods for Illumina next generation sequencing of small amounts of DNA from foodborne parasites.

Science.gov (United States)

Nascimento, Fernanda S; Wei-Pridgeon, Yuping; Arrowood, Michael J; Moss, Delynn; da Silva, Alexandre J; Talundzic, Eldin; Qvarnstrom, Yvonne

2016-11-01

Illumina library preparation methods for ultra-low input amounts were compared using genomic DNA from two foodborne parasites (Angiostrongylus cantonensis and Cyclospora cayetanensis) as examples. The Ovation Ultralow method resulted in libraries with the highest concentration and produced quality sequencing data, even when the input DNA was in the picogram range. Published by Elsevier B.V.

Research Methods and Techniques in Spanish Library and Information Science Journals (2012-2014)

Science.gov (United States)

Ferran-Ferrer, Núria; Guallar, Javier; Abadal, Ernest; Server, Adan

2017-01-01

Introduction. This study examines the research methods and techniques used in Spanish journals of library and information science, the topics addressed by papers in these journals and their authorship affiliation. Method. The researchers selected 580 papers published in the top seven Spanish LIS journals indexed in Web of Science and Scopus and…
Compare the user interface of digital libraries\\' websites between the developing and developed countries in content analysis method

Directory of Open Access Journals (Sweden)

Gholam Abbas Mousavi

2017-03-01

Full Text Available Purpose: This study performed with goals of determining the Items in designing and developing the user interface of digital libraries' websites and to determine the best digital libraries' websites and discuss their advantages and disadvantages; to analyze and compare digital libraries' websites in developing countries with those in the developed countries. Methodology: to do so, 50 digital libraries' websites were selected by purposive sampling method. By analyzing the level of development of the countries in the sample regarding their digital libraries' websites, 12 websites were classified as belonging to developing and 38 countries to developed counties. Then, their content was studied by using a qualitative content analysis. The study was conducted by using a research-constructed checklist containing 12 main categories and 44 items, whose validity was decided by content validity method. The data was analyzed in SPSS (version 16. Findings: The results showed that in terms of “online resources”, “library collection,” and “navigation”, there is a significant relationship between the digital library' user interface design in both types of countries. Results: The items of “online public access catalogue (OPAC” and “visits statistics” were observed in more developing countries’ digital libraries' websites. However, the item of “menu and submenus to introduce library' sections” was presented in more developed countries’ digital libraries' websites. Moreover, by analyzing the number of items in the selected websites, “American Memory” with 44 items, “International Children Digital Library” with 40 items, and “California” with 39 items were the best, and “Berkeley Sun Site” with 10 items was the worst website. Despite more and better quality digital libraries in developed countries, the quality of digital libraries websites in developing countries is considerable. In general, some of the newly established
Virtual shelves in a digital library: a framework for access to networked information sources.

Science.gov (United States)

Patrick, T B; Springer, G K; Mitchell, J A; Sievert, M E

1995-01-01

Develop a framework for collections-based access to networked information sources that addresses the problem of location-dependent access to information sources. This framework uses a metaphor of a virtual shelf. A virtual shelf is a general-purpose server that is dedicated to a particular information subject class. The identifier of one of these servers identifies its subject class. Location-independent call numbers are assigned to information sources. Call numbers are based on standard vocabulary codes. The call numbers are first mapped to the location-independent identifiers of virtual shelves. When access to an information resource is required, a location directory provides a second mapping of these location-independent server identifiers to actual network locations. The framework has been implemented in two different systems. One system is based on the Open System Foundation/Distributed Computing Environment and the other is based on the World Wide Web. This framework applies in new ways traditional methods of library classification and cataloging. It is compatible with two traditional styles of selecting information searching and browsing. Traditional methods may be combined with new paradigms of information searching that will be able to take advantage of the special properties of digital information. Cooperation between the library-informational science community and the informatics community can provide a means for a continuing application of the knowledge and techniques of library science to the new problems of networked information sources.
A Robust and Versatile Method of Combinatorial Chemical Synthesis of Gene Libraries via Hierarchical Assembly of Partially Randomized Modules

Science.gov (United States)

Popova, Blagovesta; Schubert, Steffen; Bulla, Ingo; Buchwald, Daniela; Kramer, Wilfried

2015-01-01

A major challenge in gene library generation is to guarantee a large functional size and diversity that significantly increases the chances of selecting different functional protein variants. The use of trinucleotides mixtures for controlled randomization results in superior library diversity and offers the ability to specify the type and distribution of the amino acids at each position. Here we describe the generation of a high diversity gene library using tHisF of the hyperthermophile Thermotoga maritima as a scaffold. Combining various rational criteria with contingency, we targeted 26 selected codons of the thisF gene sequence for randomization at a controlled level. We have developed a novel method of creating full-length gene libraries by combinatorial assembly of smaller sub-libraries. Full-length libraries of high diversity can easily be assembled on demand from smaller and much less diverse sub-libraries, which circumvent the notoriously troublesome long-term archivation and repeated proliferation of high diversity ensembles of phages or plasmids. We developed a generally applicable software tool for sequence analysis of mutated gene sequences that provides efficient assistance for analysis of library diversity. Finally, practical utility of the library was demonstrated in principle by assessment of the conformational stability of library members and isolating protein variants with HisF activity from it. Our approach integrates a number of features of nucleic acids synthetic chemistry, biochemistry and molecular genetics to a coherent, flexible and robust method of combinatorial gene synthesis. PMID:26355961
The necessity to rationalize library procedures and activities

Directory of Open Access Journals (Sweden)

Matjaž Žaucer

2007-01-01

Full Text Available The necessity of the rationalization of work and procedures in libraries due to the altered requirements and needs of users and due to the expected aggravated demands of the environment are displayed in the article. The causes for the changes in the librarianship and the causes for the changes in the environment are stated. The article analyzes the searching procedure in the Slovenian union bibliographic and catalogue database using the UDC. Upon a practical experiment it was established that the users can not make a successful use of the UDC because neither on the web nor in the database there are freely accessible UDC tables; there are also no exact usage instructions available. The outcomes of some tests in public and academic libraries reveal that the assistance of librarians with retrievals by the UDC is unpractical, timeconsuming and does not always lead to the correct result. Based on an international comparison of foreign academic libraries and one Slovenian library, the latter shows a substantial ineffectiveness in cataloging which leads to the assumption of the highdemanding or incomplete cataloguing rules. The case of the digital patent documents in one of the libraries reveals the incapability of processing of a large amount of documents according to the existing rules. The conclusion of the article is the appeal for more rational cataloging rules, for the accessibility of cataloging records directly via web search engines and for an optional indication of the UDC in the records. However, as the conditions in Slovenian libraries are not critical yet, the author has doubts about a quick response to those appeals.
Harmony Search Method: Theory and Applications

Directory of Open Access Journals (Sweden)

X. Z. Gao

2015-01-01

Full Text Available The Harmony Search (HS method is an emerging metaheuristic optimization algorithm, which has been employed to cope with numerous challenging tasks during the past decade. In this paper, the essential theory and applications of the HS algorithm are first described and reviewed. Several typical variants of the original HS are next briefly explained. As an example of case study, a modified HS method inspired by the idea of Pareto-dominance-based ranking is also presented. It is further applied to handle a practical wind generator optimal design problem.
Saskatchewan Residents’ Use of The Cochrane Library

Directory of Open Access Journals (Sweden)

Dorothy Anne Forbes

2007-11-01

Full Text Available There is strong evidence of failure to translate research findings into the health care decision-making process of consumers, practitioners and policy makers (Grimshaw, 2007. Recognizing that The Cochrane Database of Systematic Reviews contained in The Cochrane Library (the Library are the “gold standard” of systematic reviews, Saskatchewan’s Health Quality Council provided funding for a provincial license and an evaluation study. In July 2004, Saskatchewan became the first province in Canada to provide all residents with access to the Library. The primary aim of the study was to enhance and evaluate the use of the Library over three years. Since September 2004, over 46 training sessions have been conducted on searching the Library online databases. Attendees at the workshops were informed of the evaluation study and invited to participate. Those who consented to participate were telephoned following the workshops and audio-taped interviews were conducted. Usage of the Library was also tracked using data available from Wiley InterScience. Three month (n=94, six month (n=71, nine month (n=79, and 12 month (n=72 telephone interviews were conducted. Most participants were librarians (n=31.5%, followed by nurses (16.3%, therapists (7.6%, library support staff (5.4%, pharmacists (4.3%, physicians (3.3%, and others (30.5. Most were between 40 to 65 years of age (71.6% and female (92.4%. Most respondents had accessed the Library at the three-month (65.2% and six-month (64.2% follow-up interviews. However, this percent fell to 45.2% at the nine-month and 27.4% at the twelve-month interview. MeSH searches were more frequent than standard keyword searches and HTML full text retrievals were more common than PDF versions. It is assumed that HTML versions were scanned for particular information whereas PDF versions were selected when the person wished to save and read the whole review. Librarians, practitioners and consumers are more likely to be
Predicting the performance of fingerprint similarity searching.

Science.gov (United States)

Vogt, Martin; Bajorath, Jürgen

2011-01-01

Fingerprints are bit string representations of molecular structure that typically encode structural fragments, topological features, or pharmacophore patterns. Various fingerprint designs are utilized in virtual screening and their search performance essentially depends on three parameters: the nature of the fingerprint, the active compounds serving as reference molecules, and the composition of the screening database. It is of considerable interest and practical relevance to predict the performance of fingerprint similarity searching. A quantitative assessment of the potential that a fingerprint search might successfully retrieve active compounds, if available in the screening database, would substantially help to select the type of fingerprint most suitable for a given search problem. The method presented herein utilizes concepts from information theory to relate the fingerprint feature distributions of reference compounds to screening libraries. If these feature distributions do not sufficiently differ, active database compounds that are similar to reference molecules cannot be retrieved because they disappear in the "background." By quantifying the difference in feature distribution using the Kullback-Leibler divergence and relating the divergence to compound recovery rates obtained for different benchmark classes, fingerprint search performance can be quantitatively predicted.
The Digital School Library: A World-Wide Development and a Fascinating Challenge.

Science.gov (United States)

Loertscher, David

2003-01-01

Explores the academic environment of a total information system for school libraries based on the idea of a digital intranet. Discusses safety; customization; the core library collection; curriculum-specific collections; access to short-term resources; Internet access; personalized features; search engines; equity issues; and staffing. (LRW)
The JPL Library information retrieval system

Science.gov (United States)

Walsh, J.

1975-01-01

The development, capabilities, and products of the computer-based retrieval system of the Jet Propulsion Laboratory Library are described. The system handles books and documents, produces a book catalog, and provides a machine search capability. Programs and documentation are available to the public through NASA's computer software dissemination program.
Developing informational literacy among doctoral students and researchers - Case Åbo Akademi University Library and Turku University Library

Directory of Open Access Journals (Sweden)

Eva Costiander-Huldén

2013-12-01

Full Text Available In recent years, there has been a demand to include doctoral students and researchers in the curriculum for information literacy. Not only information search, but also the expertise of the librarians in scientific publishing, bibliometric analysis is demanded. As a result of the demand the two universities in Turku/Åbo have developed their research services. The libraries have also met for benchmarking and further cooperation is being discussed. 1.The implementation of three focus group interviews with 18 researchers at Åbo Akademi University The Focus Group survey methodology has its roots in social science qualitative research. It is widely used in the library world and is considered to be suitable particularly well for the evaluation and development of library services. The overall purpose with our interviews was to obtain feedback on how library users (in this case, researchers and graduate students wish ÅAUL to develop its services to better meet their needs. Three group interviews were conducted, with 6-8 participators. The following questions were, among others, discussed in every session: How do the researchers perceive the library's role in their daily work? What is the starting point for retrieving information (e.g. The MetaLib portal, Google Scholar or other? Is there a need for courses/more supervision in information search and reference management? Is there a need for tailored and integrated library services? As a result of the sessions and analysis of the group discussions a number of measures were proposed: Targeted teaching of subject-specific databases, more topic-specific sessions in the library portal and RefWorks. Compulsory information retrieval course for first year doctoral students. Information Weeks or "hands on" sessions on campus libraries. The library should participate more in workshops and seminars to increase their visibility and their services. The library should actively consider how to measure the impact and
The Searching Behavior of Remote Users: A Study of One Online Public Access Catalog (OPAC).

Science.gov (United States)

Kalin, Sally W.

1991-01-01

Describes a study that was conducted to determine whether the searching behavior of remote users of LIAS (Library Information Access System), Pennsylvania State University's online public access catalog (OPAC), differed from those using the OPAC within the library. Differences in search strategies and in user satisfaction are discussed. (eight…
FilTer BaSe: A web accessible chemical database for small compound libraries.

Science.gov (United States)

Kolte, Baban S; Londhe, Sanjay R; Solanki, Bhushan R; Gacche, Rajesh N; Meshram, Rohan J

2018-03-01

Finding novel chemical agents for targeting disease associated drug targets often requires screening of large number of new chemical libraries. In silico methods are generally implemented at initial stages for virtual screening. Filtering of such compound libraries on physicochemical and substructure ground is done to ensure elimination of compounds with undesired chemical properties. Filtering procedure, is redundant, time consuming and requires efficient bioinformatics/computer manpower along with high end software involving huge capital investment that forms a major obstacle in drug discovery projects in academic setup. We present an open source resource, FilTer BaSe- a chemoinformatics platform (http://bioinfo.net.in/filterbase/) that host fully filtered, ready to use compound libraries with workable size. The resource also hosts a database that enables efficient searching the chemical space of around 348,000 compounds on the basis of physicochemical and substructure properties. Ready to use compound libraries and database presented here is expected to aid a helping hand for new drug developers and medicinal chemists. Copyright © 2017 Elsevier Inc. All rights reserved.
E-book lending in digital libraries: systematic review

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Mehdi Alipour-Hafezi

2016-12-01

Full Text Available The purpose of this study is systematic review of e-book lending in digital libraries in order to identify the status of researches in e-book lending, exist research gaps, and their research methods. In this way, systematic review is used for study. Searching in databases in three steps finally showed 36 research resources to be studied. Findings demonstrate that researches on e-book lending are in progress and at the future this domain will be in the spotlight. Also findings showed that subjects such as e-book lending, business models and status of laws in e-book lending are the main fields that need more researches. Moreover study on research methods showed that most of the researches had done by quantitative approach and survey method.
Building maps to search the web: the method Sewcom

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Corrado Petrucco

2002-01-01

Full Text Available Seeking information on the Internet is becoming a necessity 'at school, at work and in every social sphere. Unfortunately the difficulties' inherent in the use of search engines and the use of unconscious cognitive approaches inefficient limit their effectiveness. It is in this respect presented a method, called SEWCOM that lets you create conceptual maps through interaction with search engines.
Toward Chemical Implementation of Encoded Combinatorial Libraries

DEFF Research Database (Denmark)

Nielsen, John; Janda, Kim D.

1994-01-01

The recent application of "combinatorial libraries" to supplement existing drug screening processes might simplify and accelerate the search for new lead compounds or drugs. Recently, a scheme for encoded combinatorial chemistry was put forward to surmount a number of the limitations possessed...
Students are Confident Using Federated Search Tools as much as Single Databases. A Review of: Armstrong, A. (2009. Student perceptions of federated searching vs. single database searching. Reference Services Review, 37(3, 291-303. doi:10.1108/00907320910982785

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Deena Yanofsky

2011-09-01

Full Text Available Objective – To measure students’ perceptions of the ease-of-use and efficacy of a federated search tool versus a single multidisciplinary database.Design – An evaluation worksheet, employing a combination of quantitative and qualitative questions.Setting – A required, first-year English composition course taught at the University of Illinois at Chicago (UIC.Subjects – Thirty-one undergraduate students completed and submitted the worksheet.Methods – Students attended two library instruction sessions. The first session introduced participants to basic Boolean searching (using AND only, selecting appropriate keywords and searching for books in the library catalogue. In the second library session, students were handed an evaluation worksheet and, with no introduction to the process of searching article databases, were asked to find relevant articles on a research topic of their own choosing using both a federated search tool and a single multidisciplinary database. The evaluation worksheet was divided into four sections: step-by-step instructions for accessing the single multidisciplinary database and the federated search tool; space to record search strings in both resources; space to record the titles of up to five relevant articles; and a series of quantitative and qualitative questions regarding ease-of-use, relevancy of results, overall preference (if any between the two resources, likeliness of future use and other preferred research tools. Half of the participants received a worksheet with instructions to search the federated search tool before the single database; the order was reversed for the other half of the students. The evaluation worksheet was designed to be completed in one hour.Participant responses to qualitative questions were analyzed, codified and grouped into thematic categories. If a student mentioned more than one factor in responding to a question, their response was recorded in multiple categories.Main Results �
Clinical Digital Libraries Project: design approach and exploratory assessment of timely use in clinical environments.

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Maccall, Steven L

2006-04-01

The paper describes and evaluates the use of Clinical Digital Libraries Project (CDLP) digital library collections in terms of their facilitation of timely clinical information seeking. A convenience sample of CDLP Web server log activity over a twelve-month period (7/2002 to 6/2003) was analyzed for evidence of timely information seeking after users were referred to digital library clinical topic pages from Web search engines. Sample searches were limited to those originating from medical schools (26% North American and 19% non-North American) and from hospitals or clinics (51% North American and 4% non-North American). Timeliness was determined based on a calculation of the difference between the timestamps of the first and last Web server log "hit" during each search in the sample. The calculated differences were mapped into one of three ranges: less than one minute, one to three minutes, and three to five minutes. Of the 864 searches analyzed, 48% were less than 1 minute, 41% were 1 to 3 minutes, and 11% were 3 to 5 minutes. These results were further analyzed by environment (medical schools versus hospitals or clinics) and by geographic location (North America versus non-North American). Searches reflected a consistent pattern of less than 1 minute in these environments. Though the results were not consistent on a month-by-month basis over the entire time period, data for 8 of 12 months showed that searches shorter than 1 minute predominated and data for 1 month showed an equal number of less than 1 minute and 1 to 3 minute searches. The CDLP digital library collections provided timely access to high-quality Web clinical resources when used for information seeking in medical education and hospital or clinic environments from North American and non-North American locations and consistently provided access to the sought information within the documented two-minute standard. The limitations of the use of Web server data warrant an exploratory assessment. This
Female Public Library Patrons Value the Library for Services, Programs, and Technology. A Review of: Fidishun, Dolores. “Women and the Public Library: Using Technology, Using the Library.” Library Trends 56.2 (2007: 328-43.

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Virginia Wilson

2009-03-01

Full Text Available Objective – This study attempts to give insight into why and how women use the public library and information technology, and how they learned to use the technology.Design – Qualitative survey.Setting – The research took place at the Chester County Library in Exton, Pennsylvania, USA.Subjects – One hundred and eighty-four female library patrons 18 years and older.Methods – An anonymous qualitative survey was handed out to all patrons at the ChesterCounty Library 18 years of age and older who came into the library on four separate days and times. Times were chosen to obtain a good representation of library patrons, and included daytime, evening, and weekend hours. The survey consisted of questions about library use, information sought, information seeking behaviour, technology used, and how the respondents learned to use the technology. The surveys were collated and spreadsheets were created that reported answers to yes/no and other data questions. Word documents facilitated the listing of more qualitative answers. The data were analyzed using a thematic content analysis to find themes and patterns that emerged to create grounded theory. In thematic content analysis, “the coding scheme is based on categories designed to capture the dominant themes in a text (Franzosi 184. There is no universal coding scheme, and this method requires extensive pre-testing of the scheme (Franzosi 184. Grounded theory “uses a prescribed set of procedures for analyzing data and constructing a theoretical model” from the data (Leedy and Ormrod 154.Main Results – The survey asked questions about library use, reasons for library use, using technology, finding information, and learning to use online resources. A total of 465 surveys were distributed and 329 were returned. From the surveys returned, 184 were from female patrons, 127 from male patrons, and 18 did not report gender. The data for this article are primarily taken from the 184 female
The Use of Resistivity Methods in Terrestrial Forensic Searches

Science.gov (United States)

Wolf, R. C.; Raisuddin, I.; Bank, C.

2013-12-01

The increasing use of near-surface geophysical methods in forensic searches has demonstrated the need for further studies to identify the ideal physical, environmental and temporal settings for each geophysical method. Previous studies using resistivity methods have shown promising results, but additional work is required to more accurately interpret and analyze survey findings. The Ontario Provincial Police's UCRT (Urban Search and Rescue; Chemical, Biolgical, Radiological, Nuclear and Explosives; Response Team) is collaborating with the University of Toronto and two additional universities in a multi-year study investigating the applications of near-surface geophysical methods to terrestrial forensic searches. In the summer of 2012, on a test site near Bolton, Ontario, the OPP buried weapons, drums and pigs (naked, tarped, and clothed) to simulate clandestine graves and caches. Our study aims to conduct repeat surveys using an IRIS Syscal Junior with 48 electrode switching system resistivity-meter. These surveys will monitor changes in resistivity reflecting decomposition of the object since burial, and identify the strengths and weaknesses of resistivity when used in a rural, clandestine burial setting. Our initial findings indicate the usefulness of this method, as prominent resistivity changes have been observed. We anticipate our results will help to assist law enforcement agencies in determining the type of resistivity results to expect based on time since burial, depth of burial and state of dress of the body.

Systems Analysis, Machineable Circulation Data and Library Users and Non-Users.

Science.gov (United States)

Lubans, John, Jr.

A study to be made with computer-based circulation data of the non-use and use of a large academic library is discussed. A search of the literature reveals that computer-based circulation systems can be, but have not been, utilized to provide data bases for systematic analyses of library users and resources. The data gathered in the circulation…
Bibliotek.dk: Immediate Access to Danish Libraries--A Path To Follow.

Science.gov (United States)

Hansen, Lone

Bibliotek.dk is a development project, resulting in a World Wide Web site, that gives the Danish citizen access via the Internet to search and order material in the collections of Danish public and research libraries. The citizen decides himself or herself which library he or she wants to collect the material from. Bibliotek.dk is developed in…
Rapid identification and quantitation of compounds with forensic interest using fast liquid chromatography-ion trap mass spectrometry and library searching.

Science.gov (United States)

Pihlainen, Katja; Sippola, Erkki; Kostiainen, Risto

2003-04-25

A fast liquid chromatography-electrospray tandem mass spectrometric (LC-ESI-MS-MS) method by using a monolithic column, gradient elution and ion trap mass spectrometer was developed for 14 forensically interesting and chemically different compounds. All compounds were eluted within 2.5 min and the total analysis time was 5 min including stabilisation time required for the next injection. All the compounds, basics, neutrals and acids were efficiently ionised by positive ion ESI. A laboratory library including MS-MS spectra and retention times was developed and tested. Results with 476 standard samples and 50 authentic samples showed that the compounds studied can be unambiguously identified with the library. A quantitative method was developed for the compounds using external calibration. The evaluation process showed good linearity of the method and reasonable repeatability. Limits of detection ranged from 10.0 to 50.0 ng/ml.
Borgesian Libraries and Librarians in Television Popular Culture

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Iana Konstantinova

2013-01-01

Full Text Available In the works of Jorge Luis Borges, the library appears frequently as a metaphor representative of life and its secrets. It becomes a metaphysical location, posing questions about the nature of time, life, and the universe itself. The librarian becomes a metaphysical figure, leading the search for answers to life’s questions. This article examines the way in which the Borgesian library metaphor has crossed over from the realm of literature into the realm of popular television. By examining two episodes of the BBC series Doctor Who , the TNT franchise The Librarian , and several episodes of Joss Whedon’s cult television series Buffy the Vampire Slayer , it demonstrates that the metaphysical questions posed by the library and its librarian in Borges’s short stories are quite similar to the metaphysical questions posed by the library and its librarians in popular television, demonstrating that the Borgesian library has crossed over into the realms of popular culture.
Usage Volume and Trends Indicate Academic Library Online Learning Objects and Tutorials Are Being Used

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Ruby Muriel Lavallee Warren

2017-03-01

Full Text Available A Review of: Hess, A. N., & Hristova, M. (2016. To search or to browse: How users navigate a new interface for online library tutorials. College & Undergraduate Libraries, 23(2, 168-183. http://dx.doi.org/10.1080/10691316.2014.963274 Objective – To discover how users interact with a new online interface for learning objects, user preferences for types of access when given both browsing and searching options, and user needs for tutorial subject matter. Design – Mixed methods, with quantitative analysis of web traffic and qualitative analysis of recorded search terms through grounded textual theory. Setting – An academic library in the Western United States of America. Subjects – Users of the Libraries’ online tutorials and learning objects. Methods – The researchers collected web traffic statistics and organically occurring searches from the Libraries’ tutorial access interface. They defined the collection period as the 2013/2014 academic year, with collection beginning in September 2013 and ending in April 2014. Web traffic for organic searches, facilitated searches (search results accessed through clicking on particular words in a tag cloud, and categorical browsing was collected via Google Analytics. They categorized other interaction types (accessing featured content, leaving the page, etc. under an umbrella term of “other.” Their analysis of web traffic was limited to unique page views, with unique page views defined as views registered to different browser sessions. Unique page views were analyzed to determine which types of interface interaction occurred most frequently, both on-campus and off-campus, and whether there were differences in types of interaction preferred over time or by users with different points of origin. Individual organic search keywords and phrases, and the dates and times of those searches, were separately collected and recorded. One of the researchers coded the recorded organic search terms using
A large synthetic peptide and phosphopeptide reference library for mass spectrometry–based proteomics

NARCIS (Netherlands)

Marx, H.; Lemeer, S.; Schliep, J.E.; Matheron, L.I.; Mohammed, S.; Cox, J.; Mann, M.; Heck, A.J.R.; Kuster, B.

2013-01-01

We present a peptide library and data resource of >100,000 synthetic, unmodified peptides and their phosphorylated counterparts with known sequences and phosphorylation sites. Analysis of the library by mass spectrometry yielded a data set that we used to evaluate the merits of different search
New hybrid conjugate gradient methods with the generalized Wolfe line search.

Science.gov (United States)

Xu, Xiao; Kong, Fan-Yu

2016-01-01

The conjugate gradient method was an efficient technique for solving the unconstrained optimization problem. In this paper, we made a linear combination with parameters β k of the DY method and the HS method, and putted forward the hybrid method of DY and HS. We also proposed the hybrid of FR and PRP by the same mean. Additionally, to present the two hybrid methods, we promoted the Wolfe line search respectively to compute the step size α k of the two hybrid methods. With the new Wolfe line search, the two hybrid methods had descent property and global convergence property of the two hybrid methods that can also be proved.
Implementation Of Haversine Formula And Best First Search Method In Searching Of Tsunami Evacuation Route

Science.gov (United States)

Anisya; Yoga Swara, Ganda

2017-12-01

Padang is one of the cities prone to earthquake disaster with tsunami due to its position at the meeting of two active plates, this is, a source of potentially powerful earthquake and tsunami. Central government and most offices are located in the red zone (vulnerable areas), it will also affect the evacuation of the population during the earthquake and tsunami disaster. In this study, researchers produced a system of search nearest shelter using best-first-search method. This method uses the heuristic function, the amount of cost taken and the estimated value or travel time, path length and population density. To calculate the length of the path, researchers used method of haversine formula. The value obtained from the calculation process is implemented on a web-based system. Some alternative paths and some of the closest shelters will be displayed in the system.
Expressing Intellectual Freedom: A Content Analysis of Catholic Library World from 1980 to 2015

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Megan E. Welsh

2016-12-01

Full Text Available Objective – Professional librarians have varying values relating to the topic of intellectual freedom that may or may not align with the American Library Association’s (ALA policies defining professional expectations on the topic. The personally held values and beliefs of Roman Catholic librarians and those working in libraries affiliated with Roman Catholicism are worthy of study to determine how personal religious values may translate into professional practice. The objective of this paper is to ascertain how frequently and in what context the topics of intellectual freedom and censorship were expressed in articles published in Catholic Library World (CLW, the professional journal of the Catholic Library Association (CLA from 1980 to 2015. Published content on these topics can be used as evidence to determine how this population discusses the concept of intellectual freedom. Methods – Articles relevant to these topics were retrieved from the American Theological Library Association Catholic Periodical and Literature Index (ATLA CPLI and Library, Information Science & Technology Abstracts (LISTA databases by conducting keyword searches using the terms “intellectual freedom” and censorship. Each retrieved publication was analyzed by counting the number of times the phrase “intellectual freedom” and the root censor* occurred. Through a deep reading of each publication, statements containing these search terms were then coded as positive, negative, or neutral, establishing a context for each occurrence. Results – The majority of published content supported intellectual freedom and opposed censorship. Negative content typically occurred in publications about children or school libraries. Additionally, CLW contributors did express a certain level of conflict between personally held religious values and professional values. Conclusions – This study adds to the limited research available on the intersection of personally held
Engineering Faculty Indicate High Levels of Awareness and Use of the Library but Tend to Consult Google and Google Scholar First for Research Resources

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Elaine Sullo

2016-09-01

Full Text Available A Review of: Zhang, L. (2015. Use of library services by engineering faculty at Mississippi State University, a large land grant institution. Science & Technology Libraries, 34(3, 272-286. http://dx.doi.org/10.1080/0194262X.2015.1090941 Objective – To investigate the engineering faculty’s information-seeking behaviour, experiences, awareness, and use of the university library. Design – Web-based survey questionnaire. Setting – The main campus of a state university in the United States of America. Subjects – 119 faculty members within 8 engineering departments. Methods – An email invitation to participate in a 16-item electronic survey questionnaire, with questions related to library use, was sent in the spring of 2015 to 119 engineering faculty members. Faculty were given 24 days to complete the survey, and a reminder email was sent 10 days after the original survey invitation. Main Results – Thirty-eight faculty members responded to the survey, representing a response rate of 32%. Overall, faculty had a high level of use and awareness of both online and physical library resources and services, although their awareness of certain scholarly communication services, such as data archiving and copyright advisory, was significantly lower. Faculty tend to turn to Google and Google Scholar when searching for information rather than turning to library databases. Faculty do not use social media to keep up with library news and updates. The library website, as well as liaison librarians, were cited as the primary sources for this type of information. Conclusions – The researcher concludes that librarians need to do a better job of marketing library resources, such as discipline-specific databases, as well as other library search tools. Because faculty use web search engines as a significant source of information, the author proposes further research on this behaviour, and suggests more action to educate faculty on different search tools
Uji Ketergunaan Layanan Antarmuka Magister Management Digital Library (MM-Digilib Perpustakaan Magister Manajemen Fakultas Ekonomi Universitas Indonesia

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Sri Sugianti

2016-01-01

Full Text Available A digital library is an advancement of a conventional library. Wider role of a digital library lies in its ability to give support for service via virtual/electronic/digital network. Through its revolutionary presence, a digital library needs a testfor development. One of the tests that can be used is usqge test of interface service of magister management Digital Library (MM-Digilib at Magister Management of Faculty of Economics, University of Indonesia. Based on theformula of Slovin and Nomogram Henry King, there are 8I valid samples out of 651 of master students accessing digital theses at Magister Management Library, Faculty of Economics, University of Indonesia. Out of indicators of usage test - efficiency, effictiveness, ease ofuse and ease ofinteraction of MM-Digilib is in general relatively good. Yet it needs to improve thefunction of Advanced Search in order to assist and shorten time in searching.
Expert searching in health librarianship: a literature review to identify international issues and Australian concerns.

Science.gov (United States)

Lasserre, Kaye

2012-03-01

The traditional role of health librarians as expert searchers is under challenge. The purpose of this review is to establish health librarians' views, practices and educational processes on expert searching. The search strategy was developed in LISTA and then customised for ten other databases: ALISA, PubMed, Embase, Scopus, Web of Science, CINAHL, ERIC, PsycINFO, Cochrane Library and Google Scholar. The search terms were (expert search* OR expert retriev* OR mediated search* OR information retriev*) AND librar*. The searches, completed in December 2010 and repeated in May 2011, were limited to English language publications from 2000 to 2011 (unless seminal works). Expert searching remains a key role for health librarians, especially for those supporting systematic reviews or employed as clinical librarians answering clinical questions. Although clients tend to be satisfied with searches carried out for them, improvements are required to effectively position the profession. Evidence-based guidelines, adherence to transparent standards, review of entry-level education requirements and a commitment to accredited, rigorous, ongoing professional development will ensure best practice. © 2012 The authors. Health Information and Libraries Journal © 2012 Health Libraries Group.
Retrieval of Legal Information Through Discovery Layers: A Case Study Related to Indian Law Libraries

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Kushwah, Shivpal Singh

2016-09-01

Full Text Available Purpose. The purpose of this paper is to analyze and evaluate discovery layer search tools for retrieval of legal information in Indian law libraries. This paper covers current practices in legal information retrieval with special reference to Indian academic law libraries, and analyses its importance in the domain of law.Design/Methodology/Approach. A web survey and observational study method are used to collect the data. Data related to the discovery tools were collected using email and further discussion held with the discovery layer/ tool /product developers and their representatives.Findings. Results show that most of the Indian law libraries are subscribing to bundles of legal information resources such as Hein Online, JSTOR, LexisNexis Academic, Manupatra, Westlaw India, SCC web, AIR Online (CDROM, and so on. International legal and academic resources are compatible with discovery tools because they support various standards related to online publishing and dissemination such as OAI/PMH, Open URL, MARC21, and Z39.50, but Indian legal resources such as Manupatra, Air, and SCC are not compatible with the discovery layers. The central index is one of the important components in a discovery search interface, and discovery layer services/tools could be useful for Indian law libraries also if they can include multiple legal and academic resources in their central index. But present practices and observations reveal that discovery layers are not providing facility to cover legal information resources. Therefore, in the present form, discovery tools are not very useful; they are an incomplete and half solution for Indian libraries because all available Indian legal resources available in the law libraries are not covered.Originality/Value. Very limited research or published literature is available in the area of discovery layers and their compatibility with legal information resources.
The development of search filters for adverse effects of surgical interventions in medline and Embase.

Science.gov (United States)

Golder, Su; Wright, Kath; Loke, Yoon Kong

2018-03-31

Search filter development for adverse effects has tended to focus on retrieving studies of drug interventions. However, a different approach is required for surgical interventions. To develop and validate search filters for medline and Embase for the adverse effects of surgical interventions. Systematic reviews of surgical interventions where the primary focus was to evaluate adverse effect(s) were sought. The included studies within these reviews were divided randomly into a development set, evaluation set and validation set. Using word frequency analysis we constructed a sensitivity maximising search strategy and this was tested in the evaluation and validation set. Three hundred and fifty eight papers were included from 19 surgical intervention reviews. Three hundred and fifty two papers were available on medline and 348 were available on Embase. Generic adverse effects search strategies in medline and Embase could achieve approximately 90% relative recall. Recall could be further improved with the addition of specific adverse effects terms to the search strategies. We have derived and validated a novel search filter that has reasonable performance for identifying adverse effects of surgical interventions in medline and Embase. However, we appreciate the limitations of our methods, and recommend further research on larger sample sizes and prospective systematic reviews. © 2018 The Authors Health Information and Libraries Journal published by John Wiley & Sons Ltd on behalf of Health Libraries Group.
Application of RSS in Special Libraries

Directory of Open Access Journals (Sweden)

Shima Moradi

2007-07-01

Full Text Available Despite of ever increasing scope and volume of online information content and the constant need for easy accessibility to these contents, experts in various subject matters always face time constraints when searching for information or looking up their intended resource. Meanwhile, special libraries are faced with diminishing resources, time and human resource needed for providing services and meeting the information need of the said experts. Nowadays Push Technologies, in form of RSS could be used to speed up on-time information dissemination. RSS feeds could spontaneously deliver information to the users. These could be posted on webpages or read by RSS readers. RSS has numerous applications such as web page content update, reading lists, table of contents, current awareness, guides etc. The present paper while outlining RSS as one of the next generation web tools, would point out its various advantages and applications in the new generation of libraries (Lib 2.0,particularly the special libraries. It would also offer pointers to its application in meeting the information needs of experts and users in such libraries.
Mixture-based combinatorial libraries from small individual peptide libraries: a case study on α1-antitrypsin deficiency.

Science.gov (United States)

Chang, Yi-Pin; Chu, Yen-Ho

2014-05-16

The design, synthesis and screening of diversity-oriented peptide libraries using a "libraries from libraries" strategy for the development of inhibitors of α1-antitrypsin deficiency are described. The major buttress of the biochemical approach presented here is the use of well-established solid-phase split-and-mix method for the generation of mixture-based libraries. The combinatorial technique iterative deconvolution was employed for library screening. While molecular diversity is the general consideration of combinatorial libraries, exquisite design through systematic screening of small individual libraries is a prerequisite for effective library screening and can avoid potential problems in some cases. This review will also illustrate how large peptide libraries were designed, as well as how a conformation-sensitive assay was developed based on the mechanism of the conformational disease. Finally, the combinatorially selected peptide inhibitor capable of blocking abnormal protein aggregation will be characterized by biophysical, cellular and computational methods.
A method of searching LDAP directories using XQuery

International Nuclear Information System (INIS)

Hesselroth, Ted

2011-01-01

A method by which an LDAP directory can be searched using XQuery is described. The strategy behind the tool consists of four steps. First the XQuery script is examined and relevant XPath expressions are extracted, determined to be sufficient to define all information needed to perform the query. Then the XPath expressions are converted into their equivalent LDAP search filters by use of the published LDAP schema of the service, and search requests are made to the LDAP host. The search results are then merged and converted to an XML document that conforms to the hierarchy of the LDAP schema. Finally, the XQuery script is executed on the working XML document by conventional means. Examples are given of application of the tool in the Open Science Grid, which for discovery purposes operates an LDAP server that contains Glue schema-based information on site configuration and authorization policies. The XQuery scripts compactly replace hundreds of lines of custom python code that relied on the unix ldapsearch utility. Installation of the tool is available through the Virtual Data Toolkit.
Computer‐Assisted Library Instruction and Face‐to‐Face Library Instruction Prove Equally Effective for Teaching Basic Library Skills in Academic Libraries. A review of: Zhang, Li, Watson, Erin M. and Banfield, Laura. ʺThe Efficacy of Computer‐Assisted Instruction Versus Face‐to‐Face Instruction in Academic Libraries: A Systematic Review.ʺ The Journal of Academic Librarianship 33.4 (July 2007: 478‐484.

Directory of Open Access Journals (Sweden)

Stephanie Walker

2008-03-01

Full Text Available Objective – To conduct a systematic review of several studies comparing the efficacy of face‐to‐face versus computer‐assisted instruction (CAI for teaching basic library skills to patrons of academic libraries. Design – Systematic review of existing studies (randomised controlled trials and controlled trials.Setting ‐ College and university librariesSubjects – The subjects studied were patrons of any type of academic library, whether university, college, or other postsecondary institution, receiving instruction in basic library skills. Ten studies were included in the review, of which seven were done in the United States, two in Australia, and one in Canada. The total number of subjects in all of the studies under review was 1283. Nine of the studies focused on undergraduates enrolled in specific courses(undergraduate courses ranging widely in subject area, or in one case a first year experience program; the other study focused on library instruction methods taught to students in a graduate research methods course, yet the study was still intended to measure the efficacy of library instruction methods, yet the study was still intended to measure the efficacy of library instruction methods.Methods – One included study was a randomised controlled trial; the other nine were controlled trials. The date range under consideration was for studies done between 1990 and 2005. All original studies were required to compare the efficacy of face-to-face versus CAI instruction. Both information skills and students’ reactions to receiving the instruction were considered. To identify appropriate studies, searches were done across the following library and education‐related databases: LISA, ERIC, and Library Literature. The authors screened the 728 unique studies’ bibliographic information for relevance against four criteria: studies had to be of a particular type of design (randomised controlled trials,controlled trials, cohort studies
Libraries for spectrum identification: Method of normalized coordinates versus linear correlation

International Nuclear Information System (INIS)

Ferrero, A.; Lucena, P.; Herrera, R.G.; Dona, A.; Fernandez-Reyes, R.; Laserna, J.J.

2008-01-01

In this work it is proposed that an easy solution based directly on linear algebra in order to obtain the relation between a spectrum and a spectrum base. This solution is based on the algebraic determination of an unknown spectrum coordinates with respect to a spectral library base. The identification capacity comparison between this algebraic method and the linear correlation method has been shown using experimental spectra of polymers. Unlike the linear correlation (where the presence of impurities may decrease the discrimination capacity), this method allows to detect quantitatively the existence of a mixture of several substances in a sample and, consequently, to beer in mind impurities for improving the identification
A Strategic Level for Scientific Digital LIbraries

NARCIS (Netherlands)

Feng, L.; Jeusfeld, M.A.; Hoppenbrouwers, J.

2002-01-01

Digital libraries (DLs) are a resource for answering complex questions. Up to now, such systems mainly support keyword-based searching and browsing. The mapping from a research question to keywords and the assessment whether a retrieved article is relevant to the research question are completely the

Music libraries and collections in Slovenia and abroad: characteristics and development trends

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Tanja Curhalek

2003-01-01

Full Text Available Music libraries and collections with their materials, equipment and activities differ from general libraries, which mostly contain book materials. Library users are searching daily for more non-book music materials, specific for music libraries and collections, therefore detailed research on the situation and organization of such libraries and collections should be made. A detailed research was carried out on comprehensive Slovenian music libraries and collections. Consequently, a view was obtained of the situation of music librarianship in Slovenia, using a questionnaire and by communicating with librarians of the Music Collection of the National and University Library in Ljubljana, the Library of Department of Musicology at the Faculty of Arts in Ljubljana and the Library of the Academy of Music in Ljubljana, during the years 2000 and 2002. The research showed that music librarianship is not developed enough and that the Slovene public knows little about it, while in foreign countries libraries are contemporarily developed, well organized and extended, forming professional associations.
SALP, a new single-stranded DNA library preparation method especially useful for the high-throughput characterization of chromatin openness states.

Science.gov (United States)

Wu, Jian; Dai, Wei; Wu, Lin; Wang, Jinke

2018-02-13

Next-generation sequencing (NGS) is fundamental to the current biological and biomedical research. Construction of sequencing library is a key step of NGS. Therefore, various library construction methods have been explored. However, the current methods are still limited by some shortcomings. This study developed a new NGS library construction method, Single strand Adaptor Library Preparation (SALP), by using a novel single strand adaptor (SSA). SSA is a double-stranded oligonucleotide with a 3' overhang of 3 random nucleotides, which can be efficiently ligated to the 3' end of single strand DNA by T4 DNA ligase. SALP can be started with any denatured DNA fragments such as those sheared by Tn5 tagmentation, enzyme digestion and sonication. When started with Tn5-tagmented chromatin, SALP can overcome a key limitation of ATAC-seq and become a high-throughput NGS library construction method, SALP-seq, which can be used to comparatively characterize the chromatin openness state of multiple cells unbiasly. In this way, this study successfully characterized the comparative chromatin openness states of four different cell lines, including GM12878, HepG2, HeLa and 293T, with SALP-seq. Similarly, this study also successfully characterized the chromatin openness states of HepG2 cells with SALP-seq by using 10 5 to 500 cells. This study developed a new NGS library construction method, SALP, by using a novel kind of single strand adaptor (SSA), which should has wide applications in the future due to its unique performance.
SearchSmallRNA: a graphical interface tool for the assemblage of viral genomes using small RNA libraries data.

Science.gov (United States)

de Andrade, Roberto R S; Vaslin, Maite F S

2014-03-07

Next-generation parallel sequencing (NGS) allows the identification of viral pathogens by sequencing the small RNAs of infected hosts. Thus, viral genomes may be assembled from host immune response products without prior virus enrichment, amplification or purification. However, mapping of the vast information obtained presents a bioinformatics challenge. In order to by pass the need of line command and basic bioinformatics knowledge, we develop a mapping software with a graphical interface to the assemblage of viral genomes from small RNA dataset obtained by NGS. SearchSmallRNA was developed in JAVA language version 7 using NetBeans IDE 7.1 software. The program also allows the analysis of the viral small interfering RNAs (vsRNAs) profile; providing an overview of the size distribution and other features of the vsRNAs produced in infected cells. The program performs comparisons between each read sequenced present in a library and a chosen reference genome. Reads showing Hamming distances smaller or equal to an allowed mismatched will be selected as positives and used to the assemblage of a long nucleotide genome sequence. In order to validate the software, distinct analysis using NGS dataset obtained from HIV and two plant viruses were used to reconstruct viral whole genomes. SearchSmallRNA program was able to reconstructed viral genomes using NGS of small RNA dataset with high degree of reliability so it will be a valuable tool for viruses sequencing and discovery. It is accessible and free to all research communities and has the advantage to have an easy-to-use graphical interface. SearchSmallRNA was written in Java and is freely available at http://www.microbiologia.ufrj.br/ssrna/.
Study on boundary search method for DFM mesh generation

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Li Ri

2012-08-01

Full Text Available The boundary mesh of the casting model was determined by direct calculation on the triangular facets extracted from the STL file of the 3D model. Then the inner and outer grids of the model were identified by the algorithm in which we named Inner Seed Grid Method. Finally, a program to automatically generate a 3D FDM mesh was compiled. In the paper, a method named Triangle Contraction Search Method (TCSM was put forward to ensure not losing the boundary grids; while an algorithm to search inner seed grids to identify inner/outer grids of the casting model was also brought forward. Our algorithm was simple, clear and easy to construct program. Three examples for the casting mesh generation testified the validity of the program.
Search Method Based on Figurative Indexation of Folksonomic Features of Graphic Files

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Oleg V. Bisikalo

2013-11-01

Full Text Available In this paper the search method based on usage of figurative indexation of folksonomic characteristics of graphical files is described. The method takes into account extralinguistic information, is based on using a model of figurative thinking of humans. The paper displays the creation of a method of searching image files based on their formal, including folksonomical clues.
Research support services to small and medium enterprises by university libraries in Uganda: An entrepreneurial and innovation strategy

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Robert S. Buwule

2017-10-01

Objectives: The objectives of this study were to: investigate how university libraries in Uganda are managing the universities’ research output; find out how the research output is disseminated to SMEs for their entrepreneurial activities, to understand how SMEs access and use R&I information for their entrepreneurial programmes; and propose feasible strategies of how best university libraries can re-engineer the dissemination of the research output for use by SMEs in their entrepreneurial endeavours. Method: The study used document analysis which is a qualitative data collection method. Empirical literature related to the research variables of the study was reviewed through systematic searching of manual and electronic documents on how university libraries treat their R&I information in relation to entrepreneurship. Results: The findings demonstrate that university libraries can re-engineer their R&I information services for SMEs through: repackaging R&I information in formats and languages easily accessible by SMEs; creating informal social networks for information sharing among SMEs; creation of R&I information library corners; University Library Consortia advocating for this concept; periodical announcements of new R&I information in the library through emails to SMEs; organising SME days in the library; creation of SME pages on the library website; conducting information literacy training sessions for SME entrepreneurs; and adding this concept in the library and information science curricular. Conclusion: This article discusses how university libraries, from a developing country context such as Uganda, can re-engineer research output for SMEs and use it to develop innovative solutions that can contribute positively towards SDGs and the social economic transformation of Africa at large.
Children's Input is Vital to Creating an Online Library that meets Children's Information Needs. A review of: Druin, Allison. “What Children Can Teach Us: Developing Digital Libraries for Children with Children.” The Library Quarterly 75.1 (January 2005: 20‐41.

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Susan Haigh

2006-03-01

Full Text Available Objective - Through use of an interdisciplinary research team that included children, the study aimed to demonstate that including children in the design of a digital library for children would result in some new approaches that would improve the site's usability for the target user group. Design - Case study. Setting - The research was conducted at University of Maryland over a four-year perioe and involved an interdisciplinary research team of adult researchers from information studies, computer science, education, art, and psychology as well as seven children aged 7-11. Subjects - Seven children participated in the design team over two years; 153 children were obeserved and interviewed in the design phase; and the resulting new approaches were validated post-launch by analysis of International Children's Digital Library (ICDL (http://www.icdlbooks.org users and usage patterns from November 2002- November 2003 (over 90, 000 unique users and 19, 000 optional questionnaire respondents. Method - The study included seven children in the design team for a digital library of international children's books, which resulted in new approaches to collection development, cataloguing and the search interface. In the design phase, research methods involving the seven children included brainstorming techniques, "cooperative inquiry", low tech prototyping; and lab use studies. The team also undertook observation and interviews of 153 children engaged in searching and selecting books from public library catalogues. In validating the new approaches that resulted from the design research, the team employed web log analysis, a voluntary online survey, and working with children in local schools to understand their use of ICDL. Main result - The inclusion of children's viewpoints in the design stage of ICDL had an impact in three areas: collection development, metadata, and interface design. For collection development, the research showed that kids were interested
Econometric Analysis Suggests Possible Crowding Out of Public Libraries by Book Superstores among Middle Income Families in the 1990s. A review of: Hemmeter, Jeffrey A. “Household Use of Public Libraries and Large Bookstores.” Library & Information Science Research 28.4 (Sept. 2006: 595–616.

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Stephanie Hall

2007-09-01

Full Text Available Objective – To determine the effect of large bookstores (defined as those having 20 or more employees on household library use. Design – Econometric analysis using crosssectional data sets. Setting – The United States of America. Subjects – People in over 55,000 households across the U.S.A. Methods – Data from three 1996 studies were examined using logit and multinomial logit estimation procedures: the NationalCenter for Education Statistics’ National Household Education Survey (NHES and Public Library Survey (PLS, and the U.S. Census Bureau’s County Business Patterns (CBP. The county level results of the NHEStelephone survey were merged with the county level data from the PLS and the CBP. Additionally, data on Internet use at the state level from the Statistical Abstract of the United States were incorporated into the data set. A logit regression model was used to estimate probability of library use based on several independent variables, evaluated at the mean. Main results – In general, Hemmeter found that "with regard to the impact of large bookstores on household library use, largebookstores do not appear to have an effect on overall library use among the general population” (613. While no significant changes in general library use were found among high and low income households where more large bookstores were present, nor in the population taken as a whole, middle income households (between $25,000 and $50,000 in annual income showed notable declines in library use in these situations. These effects were strongest in the areas of borrowing (200% less likely and recreational purposes (161%, but were also present in workrelated use and job searching. Hemmeter also writes that “poorer households use the library more often for job search purposes. The probability of library use for recreation,work, and consumer information increases as income increases. This effect diminishes as households get richer” (611. Finally, home
A semantics-based method for clustering of Chinese web search results

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Zhang, Hui; Wang, Deqing; Wang, Li; Bi, Zhuming; Chen, Yong

2014-01-01

Information explosion is a critical challenge to the development of modern information systems. In particular, when the application of an information system is over the Internet, the amount of information over the web has been increasing exponentially and rapidly. Search engines, such as Google and Baidu, are essential tools for people to find the information from the Internet. Valuable information, however, is still likely submerged in the ocean of search results from those tools. By clustering the results into different groups based on subjects automatically, a search engine with the clustering feature allows users to select most relevant results quickly. In this paper, we propose an online semantics-based method to cluster Chinese web search results. First, we employ the generalised suffix tree to extract the longest common substrings (LCSs) from search snippets. Second, we use the HowNet to calculate the similarities of the words derived from the LCSs, and extract the most representative features by constructing the vocabulary chain. Third, we construct a vector of text features and calculate snippets' semantic similarities. Finally, we improve the Chameleon algorithm to cluster snippets. Extensive experimental results have shown that the proposed algorithm has outperformed over the suffix tree clustering method and other traditional clustering methods.
The Weapons Laboratory Technical Library: Automating with ’Stilas’

Science.gov (United States)

1990-03-01

version of the system to LC in October 1988. -X- A small business specializing in library automation, SIRSI was founded in 1979 by library and...computer specialists, and has a strong reputation based upon the success of their UNIX-based Unicorn Collection Management System. SIRSI offers a complete...system based on the Unicorn and BRS/ Search systems. The contracted STILAS package includes UNISYS hardware, software written in the C language
Dual-mode nested search method for categorical uncertain multi-objective optimization

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Tang, Long; Wang, Hu

2016-10-01

Categorical multi-objective optimization is an important issue involved in many matching design problems. Non-numerical variables and their uncertainty are the major challenges of such optimizations. Therefore, this article proposes a dual-mode nested search (DMNS) method. In the outer layer, kriging metamodels are established using standard regular simplex mapping (SRSM) from categorical candidates to numerical values. Assisted by the metamodels, a k-cluster-based intelligent sampling strategy is developed to search Pareto frontier points. The inner layer uses an interval number method to model the uncertainty of categorical candidates. To improve the efficiency, a multi-feature convergent optimization via most-promising-area stochastic search (MFCOMPASS) is proposed to determine the bounds of objectives. Finally, typical numerical examples are employed to demonstrate the effectiveness of the proposed DMNS method.
Methods for transforming and expression screening of filamentous fungal cells with a DNA library

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Teter, Sarah; Lamsa, Michael; Cherry, Joel; Ward, Connie

2015-06-02

The present invention relates to methods for expression screening of filamentous fungal transformants, comprising: (a) isolating single colony transformants of a DNA library introduced into E. coli; (b) preparing DNA from each of the single colony E. coli transformants; (c) introducing a sample of each of the DNA preparations of step (b) into separate suspensions of protoplasts of a filamentous fungus to obtain transformants thereof, wherein each transformant contains one or more copies of an individual polynucleotide from the DNA library; (d) growing the individual filamentous fungal transformants of step (c) on selective growth medium, thereby permitting growth of the filamentous fungal transformants, while suppressing growth of untransformed filamentous fungi; and (e) measuring activity or a property of each polypeptide encoded by the individual polynucleotides. The present invention also relates to isolated polynucleotides encoding polypeptides of interest obtained by such methods, to nucleic acid constructs, expression vectors, and recombinant host cells comprising the isolated polynucleotides, and to methods of producing the polypeptides encoded by the isolated polynucleotides.
The Weakest Link: Library Catalogs.

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Young, Terrence E., Jr.

2002-01-01

Describes methods of correcting MARC records in online public access catalogs in school libraries. Highlights include in-house methods; professional resources; conforming to library cataloging standards; vendor services, including Web-based services; software specifically developed for record cleanup; and outsourcing. (LRW)
Content Analysis of Virtual Reference Data: Reshaping Library Website Design.

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Fan, Suhua Caroline; Welch, Jennifer M

2016-01-01

An academic health sciences library wanted to redesign its website to provide better access to health information in the community. Virtual reference data were used to provide information about user searching behavior. This study analyzed three years (2012-2014) of virtual reference data, including e-mail questions, text messaging, and live chat transcripts, to evaluate the library website for redesigning, especially in areas such as the home page, patrons' terminology, and issues prompting patrons to ask for help. A coding system based on information links in the current library website was created to analyze the data.
The "SAFARI" Method of Collection Study and Cooperative Acquisition for a Multi-Library Cooperative. A Manual of Procedures.

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Sinclair, Dorothy

This document examines the importance and difficulties in resource sharing and acquisition by libraries and introduces the procedures of the Site Appraisal for Area Resources Inventory (SAFARI) system as a method of comparative evaluation of subject collections among a group of libraries. Resource, or collection, sharing offers specific…
One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy.

Science.gov (United States)

Yofe, Ido; Weill, Uri; Meurer, Matthias; Chuartzman, Silvia; Zalckvar, Einat; Goldman, Omer; Ben-Dor, Shifra; Schütze, Conny; Wiedemann, Nils; Knop, Michael; Khmelinskii, Anton; Schuldiner, Maya

2016-04-01

The yeast Saccharomyces cerevisiae is ideal for systematic studies relying on collections of modified strains (libraries). Despite the significance of yeast libraries and the immense variety of available tags and regulatory elements, only a few such libraries exist, as their construction is extremely expensive and laborious. To overcome these limitations, we developed a SWAp-Tag (SWAT) method that enables one parental library to be modified easily and efficiently to give rise to an endless variety of libraries of choice. To showcase the versatility of the SWAT approach, we constructed and investigated a library of ∼1,800 strains carrying SWAT-GFP modules at the amino termini of endomembrane proteins and then used it to create two new libraries (mCherry and seamless GFP). Our work demonstrates how the SWAT method allows fast and effortless creation of yeast libraries, opening the door to new ways of systematically studying cell biology.
Library designs for generic C++ sparse matrix computations of iterative methods

Energy Technology Data Exchange (ETDEWEB)

Pozo, R.

1996-12-31

A new library design is presented for generic sparse matrix C++ objects for use in iterative algorithms and preconditioners. This design extends previous work on C++ numerical libraries by providing a framework in which efficient algorithms can be written *independent* of the matrix layout or format. That is, rather than supporting different codes for each (element type) / (matrix format) combination, only one version of the algorithm need be maintained. This not only reduces the effort for library developers, but also simplifies the calling interface seen by library users. Furthermore, the underlying matrix library can be naturally extended to support user-defined objects, such as hierarchical block-structured matrices, or application-specific preconditioners. Utilizing optimized kernels whenever possible, the resulting performance of such framework can be shown to be competitive with optimized Fortran programs.
The CERN Library

CERN Multimedia

Hester, Alec G

1968-01-01

Any advanced research centre needs a good Library. It can be regarded as a piece of equipment as vital as any machine. At the present time, the CERN Library is undergoing a number of modifications to adjust it to the changing scale of CERN's activities and to the ever increasing flood of information. This article, by A.G. Hester, former Editor of CERN COURIER who now works in the Scientific Information Service, describes the purposes, methods and future of the CERN Library.
A Fast Radio Burst Search Method for VLBI Observation

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Liu, Lei; Tong, Fengxian; Zheng, Weimin; Zhang, Juan; Tong, Li

2018-02-01

We introduce the cross-spectrum-based fast radio burst (FRB) search method for Very Long Baseline Interferometer (VLBI) observation. This method optimizes the fringe fitting scheme in geodetic VLBI data post-processing, which fully utilizes the cross-spectrum fringe phase information and therefore maximizes the power of single-pulse signals. Working with cross-spectrum greatly reduces the effect of radio frequency interference compared with using auto-power spectrum. Single-pulse detection confidence increases by cross-identifying detections from multiple baselines. By combining the power of multiple baselines, we may improve the detection sensitivity. Our method is similar to that of coherent beam forming, but without the computational expense to form a great number of beams to cover the whole field of view of our telescopes. The data processing pipeline designed for this method is easy to implement and parallelize, which can be deployed in various kinds of VLBI observations. In particular, we point out that VGOS observations are very suitable for FRB search.
Libraries of Synthetic TALE-Activated Promoters: Methods and Applications.

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Schreiber, T; Tissier, A

2016-01-01

The discovery of proteins with programmable DNA-binding specificities triggered a whole array of applications in synthetic biology, including genome editing, regulation of transcription, and epigenetic modifications. Among those, transcription activator-like effectors (TALEs) due to their natural function as transcription regulators, are especially well-suited for the development of orthogonal systems for the control of gene expression. We describe here the construction and testing of libraries of synthetic TALE-activated promoters which are under the control of a single TALE with a given DNA-binding specificity. These libraries consist of a fixed DNA-binding element for the TALE, a TATA box, and variable sequences of 19 bases upstream and 43 bases downstream of the DNA-binding element. These libraries were cloned using a Golden Gate cloning strategy making them usable as standard parts in a modular cloning system. The broad range of promoter activities detected and the versatility of these promoter libraries make them valuable tools for applications in the fine-tuning of expression in metabolic engineering projects or in the design and implementation of regulatory circuits. © 2016 Elsevier Inc. All rights reserved.

Library Design-Facilitated High-Throughput Sequencing of Synthetic Peptide Libraries.

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Vinogradov, Alexander A; Gates, Zachary P; Zhang, Chi; Quartararo, Anthony J; Halloran, Kathryn H; Pentelute, Bradley L

2017-11-13

A methodology to achieve high-throughput de novo sequencing of synthetic peptide mixtures is reported. The approach leverages shotgun nanoliquid chromatography coupled with tandem mass spectrometry-based de novo sequencing of library mixtures (up to 2000 peptides) as well as automated data analysis protocols to filter away incorrect assignments, noise, and synthetic side-products. For increasing the confidence in the sequencing results, mass spectrometry-friendly library designs were developed that enabled unambiguous decoding of up to 600 peptide sequences per hour while maintaining greater than 85% sequence identification rates in most cases. The reliability of the reported decoding strategy was additionally confirmed by matching fragmentation spectra for select authentic peptides identified from library sequencing samples. The methods reported here are directly applicable to screening techniques that yield mixtures of active compounds, including particle sorting of one-bead one-compound libraries and affinity enrichment of synthetic library mixtures performed in solution.
Fuzzy Search Method for Hi Education Information Security

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Grigory Grigorevich Novikov

2016-03-01

Full Text Available The main reason of the research is how to use fuzzy search method for information security of Hi Education or some similar purposes. So many sensitive information leaks are through non SUMMARY 149 classified documents legal publishing. That’s why many intelligence services so love to use the «mosaic» information collection method. This article is about how to prevent it.
Performance comparison of a new hybrid conjugate gradient method under exact and inexact line searches

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Ghani, N. H. A.; Mohamed, N. S.; Zull, N.; Shoid, S.; Rivaie, M.; Mamat, M.

2017-09-01

Conjugate gradient (CG) method is one of iterative techniques prominently used in solving unconstrained optimization problems due to its simplicity, low memory storage, and good convergence analysis. This paper presents a new hybrid conjugate gradient method, named NRM1 method. The method is analyzed under the exact and inexact line searches in given conditions. Theoretically, proofs show that the NRM1 method satisfies the sufficient descent condition with both line searches. The computational result indicates that NRM1 method is capable in solving the standard unconstrained optimization problems used. On the other hand, the NRM1 method performs better under inexact line search compared with exact line search.
Clinical Digital Libraries Project: design approach and exploratory assessment of timely use in clinical environments*

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MacCall, Steven L.

2006-01-01

Objective: The paper describes and evaluates the use of Clinical Digital Libraries Project (CDLP) digital library collections in terms of their facilitation of timely clinical information seeking. Design: A convenience sample of CDLP Web server log activity over a twelve-month period (7/2002 to 6/2003) was analyzed for evidence of timely information seeking after users were referred to digital library clinical topic pages from Web search engines. Sample searches were limited to those originating from medical schools (26% North American and 19% non-North American) and from hospitals or clinics (51% North American and 4% non-North American). Measurement: Timeliness was determined based on a calculation of the difference between the timestamps of the first and last Web server log “hit” during each search in the sample. The calculated differences were mapped into one of three ranges: less than one minute, one to three minutes, and three to five minutes. Results: Of the 864 searches analyzed, 48% were less than 1 minute, 41% were 1 to 3 minutes, and 11% were 3 to 5 minutes. These results were further analyzed by environment (medical schools versus hospitals or clinics) and by geographic location (North America versus non-North American). Searches reflected a consistent pattern of less than 1 minute in these environments. Though the results were not consistent on a month-by-month basis over the entire time period, data for 8 of 12 months showed that searches shorter than 1 minute predominated and data for 1 month showed an equal number of less than 1 minute and 1 to 3 minute searches. Conclusions: The CDLP digital library collections provided timely access to high-quality Web clinical resources when used for information seeking in medical education and hospital or clinic environments from North American and non–North American locations and consistently provided access to the sought information within the documented two-minute standard. The limitations of the use of
Methods of experimental settlement of contradicting data in evaluated nuclear data libraries

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V. A. Libman

2016-12-01

Full Text Available The latest versions of the evaluated nuclear data libraries (ENDLs have contradictions concerning data about neutron cross sections. To resolve this contradiction we propose the method of experimental verification. This method is based on using of the filtered neutron beams and following measurement of appropriate samples. The basic idea of the method is to modify the suited filtered neutron beam so that the differences between the neutron cross sections in accordance with different ENDLs become measurable. Demonstration of the method is given by the example of cerium, which according to the latest versions of four ENDLs has significantly different total neutron cross section.
Library Education in the ASEAN Countries.

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Atan, H. B.; Havard-Williams, P.

1987-01-01

Identifies the hierarchy of library development in Southeast Asian countries that results in the neglect of public and school libraries. Developing local library school curricula which focus on the specific needs of each country and cooperation among library schools are suggested as methods of correcting this situation. (CLB)
A new greedy search method for the design of digital IIR filter

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Ranjit Kaur

2015-07-01

Full Text Available A new greedy search method is applied in this paper to design the optimal digital infinite impulse response (IIR filter. The greedy search method is based on binary successive approximation (BSA and evolutionary search (ES. The suggested greedy search method optimizes the magnitude response and the phase response simultaneously and also finds the lowest order of the filter. The order of the filter is controlled by a control gene whose value is also optimized along with the filter coefficients to obtain optimum order of designed IIR filter. The stability constraints of IIR filter are taken care of during the design procedure. To determine the trade-off relationship between conflicting objectives in the non-inferior domain, the weighting method is exploited. The proposed approach is effectively applied to solve the multiobjective optimization problems of designing the digital low-pass (LP, high-pass (HP, bandpass (BP, and bandstop (BS filters. It has been demonstrated that this technique not only fulfills all types of filter performance requirements, but also the lowest order of the filter can be found. The computational experiments show that the proposed approach gives better digital IIR filters than the existing evolutionary algorithm (EA based methods.
Canute Rules the Waves?: Hope for E-Library Tools Facing the Challenge of the "Google Generation"

Science.gov (United States)

Myhill, Martin

2007-01-01

Purpose: To consider the findings of a recent e-resources survey at the University of Exeter Library in the context of the dominance of web search engines in academia, balanced by the development of e-library tools such as the library OPAC, OpenURL resolvers, metasearch engines, LDAP and proxy servers, and electronic resource management modules.…
Global Convergence of a Spectral Conjugate Gradient Method for Unconstrained Optimization

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Jinkui Liu

2012-01-01

Full Text Available A new nonlinear spectral conjugate descent method for solving unconstrained optimization problems is proposed on the basis of the CD method and the spectral conjugate gradient method. For any line search, the new method satisfies the sufficient descent condition gkTdk<−∥gk∥2. Moreover, we prove that the new method is globally convergent under the strong Wolfe line search. The numerical results show that the new method is more effective for the given test problems from the CUTE test problem library (Bongartz et al., 1995 in contrast to the famous CD method, FR method, and PRP method.
Information Literacy for Users at the National Medical Library of Cuba: Cochrane Library Course for the Search of Best Evidence for Clinical Decisions

Science.gov (United States)

Santana Arroyo, Sonia; del Carmen Gonzalez Rivero, Maria

2012-01-01

The National Medical Library of Cuba is currently developing an information literacy program to train users in the use of biomedical databases. This paper describes the experience with the course "Cochrane Library: Evidence-Based Medicine," which aims to teach users how to make the best use of this database, as well as the evidence-based…
Comparing the Precision of Information Retrieval of MeSH-Controlled Vocabulary Search Method and a Visual Method in the Medline Medical Database.

Science.gov (United States)

Hariri, Nadjla; Ravandi, Somayyeh Nadi

2014-01-01

Medline is one of the most important databases in the biomedical field. One of the most important hosts for Medline is Elton B. Stephens CO. (EBSCO), which has presented different search methods that can be used based on the needs of the users. Visual search and MeSH-controlled search methods are among the most common methods. The goal of this research was to compare the precision of the retrieved sources in the EBSCO Medline base using MeSH-controlled and visual search methods. This research was a semi-empirical study. By holding training workshops, 70 students of higher education in different educational departments of Kashan University of Medical Sciences were taught MeSH-Controlled and visual search methods in 2012. Then, the precision of 300 searches made by these students was calculated based on Best Precision, Useful Precision, and Objective Precision formulas and analyzed in SPSS software using the independent sample T Test, and three precisions obtained with the three precision formulas were studied for the two search methods. The mean precision of the visual method was greater than that of the MeSH-Controlled search for all three types of precision, i.e. Best Precision, Useful Precision, and Objective Precision, and their mean precisions were significantly different (P searches. Fifty-three percent of the participants in the research also mentioned that the use of the combination of the two methods produced better results. For users, it is more appropriate to use a natural, language-based method, such as the visual method, in the EBSCO Medline host than to use the controlled method, which requires users to use special keywords. The potential reason for their preference was that the visual method allowed them more freedom of action.
Normalized cDNA libraries

Science.gov (United States)

Soares, Marcelo B.; Efstratiadis, Argiris

1997-01-01

This invention provides a method to normalize a directional cDNA library constructed in a vector that allows propagation in single-stranded circle form comprising: (a) propagating the directional cDNA library in single-stranded circles; (b) generating fragments complementary to the 3' noncoding sequence of the single-stranded circles in the library to produce partial duplexes; (c) purifying the partial duplexes; (d) melting and reassociating the purified partial duplexes to moderate Cot; and (e) purifying the unassociated single-stranded circles, thereby generating a normalized cDNA library.
Relevance and Phrase Searching in Summon: looking under the hood

Directory of Open Access Journals (Sweden)

Thomas Hodge

2013-07-01

Full Text Available This article briefly examines the mechanisms behind seemingly counter-intuitive phrase search results in Serials Solutions’ discovery platform Summon. The authors use the platform’s search API to explain why users sometimes encounter greater numbers of results when typically they would expect fewer. The article explores the reasons behind the search results and the implications for library instruction.
Cummings, Merrill, and Borrelli’s Inquiry into Small Screen Use by Academic Library Users: Timing is Everything

Directory of Open Access Journals (Sweden)

Catharine Bomhold

2018-01-01

Full Text Available A Review of: Cummings, J., Merrill, A., & Borrelli, S. (2010. The use of handheld mobile devices: Their impact and implications for library services. Library Hi Tech, (281, 22-40. https://doi.org/10.1108/07378831011026670 Abstract Objective – The authors undertook this study to understand the relatively new phenomenon of handheld computing and the use of small-screen devices among academic library users. They sought to determine if users would be inclined to search the online library catalogue on their devices and, by extension, if there would be a growing demand for small-screen compatible library services. Design – Online and paper surveys were used with both closed and open questions. Respondents included students, faculty, and staff at Washington State University (WSU. Setting – Washington State University Library, Pullman, Washington, United States of America. Subjects – The survey was open to any user of the Washington State University (Pullman Library. The 206 respondents included 126 (61.2% undergraduates, 26 (12.6% graduate or professional students, 32 (15.3% WSU employees, and 15 (7.3% faculty members. Methods – A survey was distributed both online and on paper. The online version used Surveymonkey.com and participation was solicited through various social media. It was open for three months during the Spring semester, 2007. The paper version was distributed to all library users on two days in June 2007. Eighty-four online and 122 paper responses were received. Main Results – Most of the respondents (58.4% who owned a personal digital assistant (PDA or Web-enabled cell phone (WECP indicated that they would search the library catalogue on a small-screen device. Responses to the open question “How would you use the OPAC [online public access catalogue] if it was available on a PDA or WECP?” were mixed, both positive and negative. The positive responders noted the possible time savings associated with the availability of
How to Communicate with a Machine: On Reading a Public Library's OPAC

Science.gov (United States)

Saarti, Jarmo; Raivio, Jouko

2011-01-01

This article presents a reading of the user interface in one public library system. Its aim is to find out the frames and competences required and used in the communication between the computer and the patron. The authors see the computer as a text that is to be read by the user who wants to search for information from the library. The transition…
Agency Video, Audio and Imagery Library

Science.gov (United States)

Grubbs, Rodney

2015-01-01

The purpose of this presentation was to inform the ISS International Partners of the new NASA Agency Video, Audio and Imagery Library (AVAIL) website. AVAIL is a new resource for the public to search for and download NASA-related imagery, and is not intended to replace the current process by which the International Partners receive their Space Station imagery products.
The SBASE protein domain library, release 8.0: a collection of annotated protein sequence segments.

Science.gov (United States)

Murvai, J; Vlahovicek, K; Barta, E; Pongor, S

2001-01-01

SBASE 8.0 is the eighth release of the SBASE library of protein domain sequences that contains 294 898 annotated structural, functional, ligand-binding and topogenic segments of proteins, cross-referenced to most major sequence databases and sequence pattern collections. The entries are clustered into over 2005 statistically validated domain groups (SBASE-A) and 595 non-validated groups (SBASE-B), provided with several WWW-based search and browsing facilities for online use. A domain-search facility was developed, based on non-parametric pattern recognition methods, including artificial neural networks. SBASE 8.0 is freely available by anonymous 'ftp' file transfer from ftp.icgeb.trieste.it. Automated searching of SBASE can be carried out with the WWW servers http://www.icgeb.trieste.it/sbase/ and http://sbase.abc. hu/sbase/.
A new method for the construction of a mutant library with a predictable occurrence rate using Poisson distribution.

Science.gov (United States)

Seong, Ki Moon; Park, Hweon; Kim, Seong Jung; Ha, Hyo Nam; Lee, Jae Yung; Kim, Joon

2007-06-01

A yeast transcriptional activator, Gcn4p, induces the expression of genes that are involved in amino acid and purine biosynthetic pathways under amino acid starvation. Gcn4p has an acidic activation domain in the central region and a bZIP domain in the C-terminus that is divided into the DNA-binding motif and dimerization leucine zipper motif. In order to identify amino acids in the DNA-binding motif of Gcn4p which are involved in transcriptional activation, we constructed mutant libraries in the DNA-binding motif through an innovative application of random mutagenesis. Mutant library made by oligonucleotides which were mutated randomly using the Poisson distribution showed that the actual mutation frequency was in good agreement with expected values. This method could save the time and effort to create a mutant library with a predictable mutation frequency. Based on the studies using the mutant libraries constructed by the new method, the specific residues of the DNA-binding domain in Gcn4p appear to be involved in the transcriptional activities on a conserved binding site.
Best methods for evaluating educational impact: a comparison of the efficacy of commonly used measures of library instruction.

Science.gov (United States)

Schilling, Katherine; Applegate, Rachel

2012-10-01

Libraries are increasingly called upon to demonstrate student learning outcomes and the tangible benefits of library educational programs. This study reviewed and compared the efficacy of traditionally used measures for assessing library instruction, examining the benefits and drawbacks of assessment measures and exploring the extent to which knowledge, attitudes, and behaviors actually paralleled demonstrated skill levels. An overview of recent literature on the evaluation of information literacy education addressed these questions: (1) What evaluation measures are commonly used for evaluating library instruction? (2) What are the pros and cons of popular evaluation measures? (3) What are the relationships between measures of skills versus measures of attitudes and behavior? Research outcomes were used to identify relationships between measures of attitudes, behaviors, and skills, which are typically gathered via attitudinal surveys, written skills tests, or graded exercises. Results provide useful information about the efficacy of instructional evaluation methods, including showing significant disparities between attitudes, skills, and information usage behaviors. This information can be used by librarians to implement the most appropriate evaluation methods for measuring important variables that accurately demonstrate students' attitudes, behaviors, or skills.
Open Shelves/Closed Shelves in Research Libraries

Science.gov (United States)

Rovelstad, Mathilde V.

1976-01-01

Traces the traditional method of making books accessible through their topical arrangement on library shelves, outlines the reasons for the abandonment of this method in European research libraries, explores its modified reappearance in postwar academic libraries, and cites modern arguments against the practice of making an entire research…

Improving Communication between Postgraduate Researchers and the University Library: A Case Study at De Montfort University Library and Learning Services

Science.gov (United States)

Petch, Melanie; Fraser, Katie; Rush, Nathan; Cope, Alan; Lowe, Julie

2016-01-01

A well-established postgraduate researcher development program has existed at De Montfort University for many years. Library and Learning Services include modules on literature searching skills and critical appraisal. However, we recognized that researchers seemed to be disengaged with the services on offer. This concern informed a research…
FRDS.Broker Library

DEFF Research Database (Denmark)

2018-01-01

The FRDS.Broker library is a teaching oriented implementation of the Broker architectural pattern for distributed remote method invocation. It defines the central roles of the pattern and provides implementations of those roles that are not domain/use case specific. It provides a JSON based (GSon...... library) Requestor implementation, and implementations of the ClientRequestHandler and ServerRequestHandler roles in both a Java socket based and a Http/URI tunneling based variants. The latter us based upon the UniRest and Spark-Java libraries. The Broker pattern and the source code is explained...
The Specification of Science Education Programs in the Local Public Library: Focusing on the Programs In G-city

Directory of Open Access Journals (Sweden)

In-Ja Ahn*

2012-06-01

Full Text Available The city of 'G' has been made a number of achievements with its science program as a part of public library's cultural program during the last 5 years. Recently, the national science centre has been established in the same city, the debate is now needed whether the science program in the public library have reasons to be maintained or to be reduced. The aim of this research is on the operating strategies of the science program in the public library. The research methods include case studies of operational strategies in domestic and foreign science centre, the level of satisfaction of local citizen on the science program, the vision of science program in the advancement of public library in the century. In results, the research proposes that the science program in public library should be maintained, but with locally characterised programs. In addition, the study also advised on the provision of scientific information, the strengthened search functions, and the development of user-centred services for those in science fields.
Metadata In, Library Out. A Simple, Robust Digital Library System

Directory of Open Access Journals (Sweden)

Tonio Loewald

2010-06-01

Full Text Available Tired of being held hostage to expensive systems that did not meet our needs, the University of Alabama Libraries developed an XML schema-agnostic, light-weight digital library delivery system based on the principles of "Keep It Simple, Stupid!" Metadata and derivatives reside in openly accessible web directories, which support the development of web agents and new usability software, as well as modification and complete retrieval at any time. The file name structure is echoed in the file system structure, enabling the delivery software to make inferences about relationships, sequencing, and complex object structure without having to encapsulate files in complex metadata schemas. The web delivery system, Acumen, is built of PHP, JSON, JavaScript and HTML5, using MySQL to support fielded searching. Recognizing that spreadsheets are more user-friendly than XML, an accompanying widget, Archivists Utility, transforms spreadsheets into MODS based on rules selected by the user. Acumen, Archivists Utility, and all supporting software scripts will be made available as open source.
National Agricultural Library | United States Department of Agriculture

Science.gov (United States)

Skip to main content Home National Agricultural Library United States Department of Agriculture Ag Terms of Service Frequently Asked Questions Policies and Documentation Ag Data Commons Monthly Metrics News Contact Us Search ï Log inRegister Home Home About Policies and Documentation Ag Data Commons
Non-contact method of search and analysis of pulsating vessels

Science.gov (United States)

Avtomonov, Yuri N.; Tsoy, Maria O.; Postnov, Dmitry E.

2018-04-01

Despite the variety of existing methods of recording the human pulse and a solid history of their development, there is still considerable interest in this topic. The development of new non-contact methods, based on advanced image processing, caused a new wave of interest in this issue. We present a simple but quite effective method for analyzing the mechanical pulsations of blood vessels lying close to the surface of the skin. Our technique is a modification of imaging (or remote) photoplethysmography (i-PPG). We supplemented this method with the addition of a laser light source, which made it possible to use other methods of searching for the proposed pulsation zone. During the testing of the method, several series of experiments were carried out with both artificial oscillating objects as well as with the target signal source (human wrist). The obtained results show that our method allows correct interpretation of complex data. To summarize, we proposed and tested an alternative method for the search and analysis of pulsating vessels.
PENGUJIAN COGNITIVE WALKTHROUGH ANTARMUKA PERPUSTAKAAN DIGITAL (E-LIBRARY PUSAT DOKUMENTASI DAN INFORMASI ILMIAH – LIPI (PDII-LIPI

Directory of Open Access Journals (Sweden)

Ira Maryati

2014-06-01

Full Text Available Interface design has a significant role towards the successful of digital librarys application use. Digital libraryservices developed by Centre for Scientific Documentation and Information - Indonesian Institute of Sciences (PDII-LIPI has yet to be evaluated. This research analyzed the design of the web interface of PDII-LIPI’s digitallibraries using the method of cognitive walkthrough (CW. The aim of the research is to identify user constraints inusing PDII-LIPI’s digital libraries. Object of this study are three menus in digital library web interface that is “KaryaIlmiah Indonesia”, “Buku Elektronik”, and “Jurnal Indonesia (ISJD”. CW testing parameters for PDII-LIPI’s digitallibrary interface consists of the successful completion of the task, and the effectiveness of the task. The successfulcompletion of the task was assessed by comparing the standard time with task completion time by respondents. Effectiveness accessed based on the processing time of each stage and the number of mistakes made by therespondent. The test results showed that all respondents successfully completed the task with the time that goesbeyond the standard set time. The analysis was conducted on all test results indicate that the obstacles faced byusers in general are finding menu of “E-Library”, specify the search facility is used, and searching the articles.
Medical literature searches: a comparison of PubMed and Google Scholar.

Science.gov (United States)

Nourbakhsh, Eva; Nugent, Rebecca; Wang, Helen; Cevik, Cihan; Nugent, Kenneth

2012-09-01

Medical literature searches provide critical information for clinicians. However, the best strategy for identifying relevant high-quality literature is unknown. We compared search results using PubMed and Google Scholar on four clinical questions and analysed these results with respect to article relevance and quality. Abstracts from the first 20 citations for each search were classified into three relevance categories. We used the weighted kappa statistic to analyse reviewer agreement and nonparametric rank tests to compare the number of citations for each article and the corresponding journals' impact factors. Reviewers ranked 67.6% of PubMed articles and 80% of Google Scholar articles as at least possibly relevant (P = 0.116) with high agreement (all kappa P-values PubMed searches and Google Scholar searches often identify different articles. In this study, Google Scholar articles were more likely to be classified as relevant, had higher numbers of citations and were published in higher impact factor journals. The identification of frequently cited articles using Google Scholar for searches probably has value for initial literature searches. © 2012 The authors. Health Information and Libraries Journal © 2012 Health Libraries Group.
Getting to Know Library Users' Needs

DEFF Research Database (Denmark)

Harbo, Karen; Hansen, Thomas Erlandson V.

2012-01-01

'Meeting the User' is a programme committee under the Danish Electronic Research Library. As a development group at a national level we see our role as facilitating an innovative culture within academic libraries, focusing on users' needs and the way libraries meet them. In collaboration...... a description of the above-mentioned methods, valuable experiences from the workshop, a presentation of the concept and concrete tools, discussion of the concept of user logic and library services, and the seven principles for human-centered innovation in relation to libraries, a short list of studies carried...... with a consultancy firm, the commitee organized a travelling workshop in four cities in 2010. The workshop introduced practical ways for library staff to get to know their users' needs for services and was based on anthropological methods. The travelling workshop was part of a larger project called 'A Journey...
Connecting Music and Place: Exploring Library Collection Data Using Geo-visualizations

Directory of Open Access Journals (Sweden)

Carolyn Doi

2017-06-01

Full Text Available Abstract Objectives – This project had two stated objectives: 1 to compare the location and concentration of Saskatchewan-based large ensembles (bands, orchestras, choirs within the province, with the intention to draw conclusions about the history of community-based musical activity within the province; and 2 to enable location-based browsing of Saskatchewan music materials through an interactive search interface. Methods – Data was harvested from MARC metadata found in the library catalogue for a special collection of Saskatchewan music at the University of Saskatchewan. Microsoft Excel and OpenRefine were used to screen, clean, and enhance the dataset. Data was imported into ArcGIS software, where it was plotted using a geo-visualization showing location and concentrations of musical activity by large ensembles within the province. The geo-visualization also allows users to filter results based on the ensemble type (band, orchestra, or choir. Results – The geo-visualization shows that albums from large community ensembles appear across the province, in cities and towns of all sizes. The ensembles are concentrated in the southern portion of the province and there is a correlation between population density and ensemble location. Choral ensembles are more prevalent than bands and orchestras, and appear more widely across the province, whereas bands and orchestras are concentrated around larger centres. Conclusions – Library catalogue data contains unique information for research based on special collections, though additional cleaning is needed. Using geospatial visualizations to navigate collections allows for more intuitive searching by location, and allow users to compare facets. While not appropriate for all kinds of searching, maps are useful for browsing and for location-based searches. Information is displayed in a visual way that allows users to explore and connect with other platforms for more information.
Developing a Grid-based search and categorization tool

CERN Document Server

Haya, Glenn; Vigen, Jens

2003-01-01

Grid technology has the potential to improve the accessibility of digital libraries. The participants in Project GRACE (Grid Search And Categorization Engine) are in the process of developing a search engine that will allow users to search through heterogeneous resources stored in geographically distributed digital collections. What differentiates this project from current search tools is that GRACE will be run on the European Data Grid, a large distributed network, and will not have a single centralized index as current web search engines do. In some cases, the distributed approach offers advantages over the centralized approach since it is more scalable, can be used on otherwise inaccessible material, and can provide advanced search options customized for each data source.
100 Colleges Sign Up with Google to Speed Access to Library Resources

Science.gov (United States)

Young, Jeffrey R.

2005-01-01

More than 100 colleges and universities have arranged to give people using the Google Scholar search engine on their campuses more-direct access to library materials. Google Scholar is a free tool that searches scholarly materials on the Web and in academic databases. The new arrangements essentially let Google know which online databases the…
Orientation Programs to the Virtual National Libraries in the Arab ...

African Journals Online (AJOL)

pc

2018-03-05

teaching the strategies of web search engines" and "teaching the standards of .... For example, YouTube is used to market particular services and products. ..... [11] Liu, Q., Lo, P., & Itsumura, H. , Measuring the Importance of Library.
Reverse screening methods to search for the protein targets of chemopreventive compounds

Science.gov (United States)

Huang, Hongbin; Zhang, Guigui; Zhou, Yuquan; Lin, Chenru; Chen, Suling; Lin, Yutong; Mai, Shangkang; Huang, Zunnan

2018-05-01

This article is a systematic review of reverse screening methods used to search for the protein targets of chemopreventive compounds or drugs. Typical chemopreventive compounds include components of traditional Chinese medicine, natural compounds and Food and Drug Administration (FDA)-approved drugs. Such compounds are somewhat selective but are predisposed to bind multiple protein targets distributed throughout diverse signaling pathways in human cells. In contrast to conventional virtual screening, which identifies the ligands of a targeted protein from a compound database, reverse screening is used to identify the potential targets or unintended targets of a given compound from a large number of receptors by examining their known ligands or crystal structures. This method, also known as in silico or computational target fishing, is highly valuable for discovering the target receptors of query molecules from terrestrial or marine natural products, exploring the molecular mechanisms of chemopreventive compounds, finding alternative indications of existing drugs by drug repositioning, and detecting adverse drug reactions and drug toxicity. Reverse screening can be divided into three major groups: shape screening, pharmacophore screening and reverse docking. Several large software packages, such as Schrödinger and Discovery Studio; typical software/network services such as ChemMapper, PharmMapper, idTarget and INVDOCK; and practical databases of known target ligands and receptor crystal structures, such as ChEMBL, BindingDB and the Protein Data Bank (PDB), are available for use in these computational methods. Different programs, online services and databases have different applications and constraints. Here, we conducted a systematic analysis and multilevel classification of the computational programs, online services and compound libraries available for shape screening, pharmacophore screening and reverse docking to enable non-specialist users to quickly learn and
A comparison of two search methods for determining the scope of systematic reviews and health technology assessments.

Science.gov (United States)

Forsetlund, Louise; Kirkehei, Ingvild; Harboe, Ingrid; Odgaard-Jensen, Jan

2012-01-01

This study aims to compare two different search methods for determining the scope of a requested systematic review or health technology assessment. The first method (called the Direct Search Method) included performing direct searches in the Cochrane Database of Systematic Reviews (CDSR), Database of Abstracts of Reviews of Effects (DARE) and the Health Technology Assessments (HTA). Using the comparison method (called the NHS Search Engine) we performed searches by means of the search engine of the British National Health Service, NHS Evidence. We used an adapted cross-over design with a random allocation of fifty-five requests for systematic reviews. The main analyses were based on repeated measurements adjusted for the order in which the searches were conducted. The Direct Search Method generated on average fewer hits (48 percent [95 percent confidence interval {CI} 6 percent to 72 percent], had a higher precision (0.22 [95 percent CI, 0.13 to 0.30]) and more unique hits than when searching by means of the NHS Search Engine (50 percent [95 percent CI, 7 percent to 110 percent]). On the other hand, the Direct Search Method took longer (14.58 minutes [95 percent CI, 7.20 to 21.97]) and was perceived as somewhat less user-friendly than the NHS Search Engine (-0.60 [95 percent CI, -1.11 to -0.09]). Although the Direct Search Method had some drawbacks such as being more time-consuming and less user-friendly, it generated more unique hits than the NHS Search Engine, retrieved on average fewer references and fewer irrelevant results.
Strategic marketing planning in library

Directory of Open Access Journals (Sweden)

Karmen Štular-Sotošek

2000-01-01

Full Text Available The article is based on the idea that every library can design instruments for creating events and managing the important resources of today's world, especially to manage the changes. This process can only be successful if libraries use adequate marketing methods. Strategic marketing planning starts with the analysis of library's mission, its objectives, goals and corporate culture. By analysing the public environment, the competitive environment and the macro environment, libraries recognise their opportunities and threats. These analyses are the foundations for library definitions: What does the library represent?, What does it aspire to? Which goals does it want to reach? What kind of marketing strategy will it use for its target market?
Euler European Libraries and Electronic Resources in Mathematical Sciences

CERN Document Server

The Euler Project. Karlsruhe

The European Libraries and Electronic Resources (EULER) Project in Mathematical Sciences provides the EulerService site for searching out "mathematical resources such as books, pre-prints, web-pages, abstracts, proceedings, serials, technical reports preprints) and NetLab (for Internet resources), this outstanding engine is capable of simple, full, and refined searches. It also offers a browse option, which responds to entries in the author, keyword, and title fields. Further information about the Project is provided at the EULER homepage.
Searching for Truth: Internet Search Patterns as a Method of Investigating Online Responses to a Russian Illicit Drug Policy Debate

Science.gov (United States)

Gillespie, James A; Quinn, Casey

2012-01-01

Background This is a methodological study investigating the online responses to a national debate over an important health and social problem in Russia. Russia is the largest Internet market in Europe, exceeding Germany in the absolute number of users. However, Russia is unusual in that the main search provider is not Google, but Yandex. Objective This study had two main objectives. First, to validate Yandex search patterns against those provided by Google, and second, to test this method's adequacy for investigating online interest in a 2010 national debate over Russian illicit drug policy. We hoped to learn what search patterns and specific search terms could reveal about the relative importance and geographic distribution of interest in this debate. Methods A national drug debate, centering on the anti-drug campaigner Egor Bychkov, was one of the main Russian domestic news events of 2010. Public interest in this episode was accompanied by increased Internet search. First, we measured the search patterns for 13 search terms related to the Bychkov episode and concurrent domestic events by extracting data from Google Insights for Search (GIFS) and Yandex WordStat (YaW). We conducted Spearman Rank Correlation of GIFS and YaW search data series. Second, we coded all 420 primary posts from Bychkov's personal blog between March 2010 and March 2012 to identify the main themes. Third, we compared GIFS and Yandex policies concerning the public release of search volume data. Finally, we established the relationship between salient drug issues and the Bychkov episode. Results We found a consistent pattern of strong to moderate positive correlations between Google and Yandex for the terms "Egor Bychkov" (r s = 0.88, P < .001), “Bychkov” (r s = .78, P < .001) and “Khimki”(r s = 0.92, P < .001). Peak search volumes for the Bychkov episode were comparable to other prominent domestic political events during 2010. Monthly search counts were 146,689 for “Bychkov” and
Constance Mellon Demonstrated that College Freshmen Are Afraid of Academic Libraries. A review of: Mellon, Constance A. “Library Anxiety: A Grounded Theory and Its Development.” College & Research Libraries 47 (1986: 160-65.

Directory of Open Access Journals (Sweden)

Edgar Bailey

2008-09-01

Full Text Available Objective – To better understand the feelings of college freshmen engaged in their first research project using an academic library.Design – Interpretive study involving analysis of personal writing describing the students’ research process and their reactions to it.Setting – A medium-sized public university in the southeastern United States.Subjects – Students in freshman English courses.Methods – English instructors assigned students to maintain search journals in which the students recorded a detailed description of their research process and the feelings they experienced while conducting research. In addition, students had to write an end-of- semester, in-class essay in which they discussed their initial reactions to the research project and how their feelings evolved over the semester. The journals and essays were analyzed using the “constant comparative” method developed by Glaser and Strauss to identify “recurrent ‘themes’” (161. Main Results – 75 to 85 per cent of the students reported feelings of “fear or anxiety” when confronted with the research assignment. More specifically, they expressed a sense of being “lost”. This feeling derived from four causes: “(1 the size of the library; (2 a lack of knowledge about where things were located; (3 how to begin, and (4 what to do” (162. Spurred by the question of why students did not seek help from their professors or a librarian, Mellon re-examined the data and uncovered two additional prevalent feelings. Most students tended to believe that their fellow students did not share their lack of library skills. They were ashamed of what they considered their own inadequacy and were, therefore, unwilling to reveal it by asking for assistance (162.Conclusions – The original objective of Mellon’s study was to gain information that would be useful in improving bibliographic instruction in her library. The discovery of the extent of students’ apprehension
[cDNA library construction from panicle meristem of finger millet].

Science.gov (United States)

Radchuk, V; Pirko, Ia V; Isaenkov, S V; Emets, A I; Blium, Ia B

2014-01-01

The protocol for production of full-size cDNA using SuperScript Full-Length cDNA Library Construction Kit II (Invitrogen) was tested and high quality cDNA library from meristematic tissue of finger millet panicle (Eleusine coracana (L.) Gaertn) was created. The titer of obtained cDNA library comprised 3.01 x 10(5) CFU/ml in avarage. In average the length of cDNA insertion consisted about 1070 base pairs, the effectivity of cDNA fragment insertions--99.5%. The selective sequencing of cDNA clones from created library was performed. The sequences of cDNA clones were identified with usage of BLAST-search. The results of cDNA library analysis and selective sequencing represents prove good functionality and full length character of inserted cDNA clones. Obtained cDNA library from meristematic tissue of finger millet panicle represents good and valuable source for isolation and identification of key genes regulating metabolism and meristematic development and for mining of new molecular markers to conduct out high quality genetic investigations and molecular breeding as well.

Research on Large-Scale Road Network Partition and Route Search Method Combined with Traveler Preferences

Directory of Open Access Journals (Sweden)

De-Xin Yu

2013-01-01

Full Text Available Combined with improved Pallottino parallel algorithm, this paper proposes a large-scale route search method, which considers travelers’ route choice preferences. And urban road network is decomposed into multilayers effectively. Utilizing generalized travel time as road impedance function, the method builds a new multilayer and multitasking road network data storage structure with object-oriented class definition. Then, the proposed path search algorithm is verified by using the real road network of Guangzhou city as an example. By the sensitive experiments, we make a comparative analysis of the proposed path search method with the current advanced optimal path algorithms. The results demonstrate that the proposed method can increase the road network search efficiency by more than 16% under different search proportion requests, node numbers, and computing process numbers, respectively. Therefore, this method is a great breakthrough in the guidance field of urban road network.
Science photo library

CERN Document Server

1999-01-01

SPL [Science Photo Library] holds a wide range of pictures on all aspects of science, medicine and technology. The pictures come with detailed captions and are available as high quality transparencies in medium or 35mm format. Digital files can be made available on request. Our website provides low resolution files of the pictures in this catalogue, which you can search and download for layout presentation use once you have registered. High resolution files or reproduction are available on request and can be delivered to you by disk or ISDN. Visit the online catalog: www.sciencephoto.com
School libraries Pathfinders

Directory of Open Access Journals (Sweden)

Shideh Taleban

2009-01-01

Full Text Available School library represents one of the important locations suited for offering reference services. The skill set necessary in order to use information resources, is called information literacy. When discussing information literacy and means of enhancing it, the first thing that comes to mind is the classroom for it is in schools that the foundation for learning skills is laid. Pathfinders have been used by libraries and librarians for guiding patrons to the required sources and answering their research questions since 1970’s. It is far different from a bibliography in as much as it does not necessarily include a complete list of available resources on a given topic. Nevertheless it provides sufficient basic resources for research for the patrons. Nowadays pathfinders are prepared by teacher-librarian or with the help of teachers at school so as to assist students in searching their prescribed assignments. The present paper offers definition of pathfinder, creation of pathfinders in schools, type of pathfinders, pathfinders characteristics, pathfinder elements as well as how to design pathfinders for children and teenagers.
Morphological Interpretation of Reflectance Spectrum (MIRS using libraries looking towards soil classification

Directory of Open Access Journals (Sweden)

José Alexandre Melo Demattê

2014-12-01

Full Text Available The search for tools to perform soil surveying faster and cheaper has led to the development of technological innovations such as remote sensing (RS and the so-called spectral libraries in recent years. However, there are no studies which collate all the RS background to demonstrate how to use this technology for soil classification. The present study aims to describe a simple method of how to classify soils by the morphology of spectra associated with a quantitative view (400-2,500 nm. For this, we constructed three spectral libraries: (i one for quantitative model performance; (ii a second to function as the spectral patterns; and (iii a third to serve as a validation stage. All samples had their chemical and granulometric attributes determined by laboratory analysis and prediction models were created based on soil spectra. The system is based on seven steps summarized as follows: i interpretation of the spectral curve intensity; ii observation of the general shape of curves; iii evaluation of absorption features; iv comparison of spectral curves between the same profile horizons; v quantification of soil attributes by spectral library models; vi comparison of a pre-existent spectral library with unknown profile spectra; vii most probable soil classification. A soil cannot be classified from one spectral curve alone. The behavior between the horizons of a profile, however, was correlated with its classification. In fact, the validation showed 85 % accuracy between the Morphological Interpretation of Reflectance Spectrum (MIRS method and the traditional classification, showing the importance and potential of a combination of descriptive and quantitative evaluations.
Adoption of open source software in library management: an ...

African Journals Online (AJOL)

This literature and practical knowledge based opinion paper explored Koha software, bringing to limelight its applicability in the library. The various modules contained in the software (Circulation, Patrons, Advanced Search/OPAC, Cataloguing, Serials, Acquisition, Report and Tools) and the various specific services that ...
A human-machine interface evaluation method: A difficulty evaluation method in information searching (DEMIS)

International Nuclear Information System (INIS)

Ha, Jun Su; Seong, Poong Hyun

2009-01-01

A human-machine interface (HMI) evaluation method, which is named 'difficulty evaluation method in information searching (DEMIS)', is proposed and demonstrated with an experimental study. The DEMIS is based on a human performance model and two measures of attentional-resource effectiveness in monitoring and detection tasks in nuclear power plants (NPPs). Operator competence and HMI design are modeled to be most significant factors to human performance. One of the two effectiveness measures is fixation-to-importance ratio (FIR) which represents attentional resource (eye fixations) spent on an information source compared to importance of the information source. The other measure is selective attention effectiveness (SAE) which incorporates FIRs for all information sources. The underlying principle of the measures is that the information source should be selectively attended to according to its informational importance. In this study, poor performance in information searching tasks is modeled to be coupled with difficulties caused by poor mental models of operators or/and poor HMI design. Human performance in information searching tasks is evaluated by analyzing the FIR and the SAE. Operator mental models are evaluated by a questionnaire-based method. Then difficulties caused by a poor HMI design are evaluated by a focused interview based on the FIR evaluation and then root causes leading to poor performance are identified in a systematic way.
About the Library - Betty Petersen Memorial Library

Science.gov (United States)

branch library of the NOAA Central Library. The library serves the NOAA Science Center in Camp Springs , Maryland. History and Mission: Betty Petersen Memorial Library began as a reading room in the NOAA Science Science Center staff and advises the library on all aspects of the library program. Library Newsletters
News from the Library : Citation counts: Web of Science @ CERN

CERN Multimedia

CERN Library

2010-01-01

The online information resources available to the CERN Community have recently increased by an additional database: Web of Science. WoS is a collection of several databases, among them the Science Citation Index, the Conference Proceedings Index and the Journal Citation Reports. The first two products allow you to perform subject, author and title searches, and most importantly you can obtain a list of papers citing a specific article, or navigate to the articles cited by the same article. Besides the retrieval and navigation features, analytical tools allow you to produce statistics and graphs describing the impact of a publication. Finally, the Journal Citation Reports database provides you with the well known – and often disputed – Impact Factor. Access to Web of Science: http://library.web.cern.ch/library/Library/wos.html Please provide feedback to library.desk@cern.ch.
Beam angle optimization for intensity-modulated radiation therapy using a guided pattern search method

International Nuclear Information System (INIS)

Rocha, Humberto; Dias, Joana M; Ferreira, Brígida C; Lopes, Maria C

2013-01-01

Generally, the inverse planning of radiation therapy consists mainly of the fluence optimization. The beam angle optimization (BAO) in intensity-modulated radiation therapy (IMRT) consists of selecting appropriate radiation incidence directions and may influence the quality of the IMRT plans, both to enhance better organ sparing and to improve tumor coverage. However, in clinical practice, most of the time, beam directions continue to be manually selected by the treatment planner without objective and rigorous criteria. The goal of this paper is to introduce a novel approach that uses beam’s-eye-view dose ray tracing metrics within a pattern search method framework in the optimization of the highly non-convex BAO problem. Pattern search methods are derivative-free optimization methods that require a few function evaluations to progress and converge and have the ability to better avoid local entrapment. The pattern search method framework is composed of a search step and a poll step at each iteration. The poll step performs a local search in a mesh neighborhood and ensures the convergence to a local minimizer or stationary point. The search step provides the flexibility for a global search since it allows searches away from the neighborhood of the current iterate. Beam’s-eye-view dose metrics assign a score to each radiation beam direction and can be used within the pattern search framework furnishing a priori knowledge of the problem so that directions with larger dosimetric scores are tested first. A set of clinical cases of head-and-neck tumors treated at the Portuguese Institute of Oncology of Coimbra is used to discuss the potential of this approach in the optimization of the BAO problem. (paper)
Merchandising Techniques and Libraries.

Science.gov (United States)

Green, Sylvie A.

1981-01-01

Proposes that libraries employ modern booksellers' merchandising techniques to improve circulation of library materials. Using displays in various ways, the methods and reasons for weeding out books, replacing worn book jackets, and selecting new books are discussed. Suggestions for learning how to market and 11 references are provided. (RBF)
A Fragment-Based Method of Creating Small-Molecule Libraries to Target the Aggregation of Intrinsically Disordered Proteins.

Science.gov (United States)

Joshi, Priyanka; Chia, Sean; Habchi, Johnny; Knowles, Tuomas P J; Dobson, Christopher M; Vendruscolo, Michele

2016-03-14

The aggregation process of intrinsically disordered proteins (IDPs) has been associated with a wide range of neurodegenerative disorders, including Alzheimer's and Parkinson's diseases. Currently, however, no drug in clinical use targets IDP aggregation. To facilitate drug discovery programs in this important and challenging area, we describe a fragment-based approach of generating small-molecule libraries that target specific IDPs. The method is based on the use of molecular fragments extracted from compounds reported in the literature to inhibit of the aggregation of IDPs. These fragments are used to screen existing large generic libraries of small molecules to form smaller libraries specific for given IDPs. We illustrate this approach by describing three distinct small-molecule libraries to target, Aβ, tau, and α-synuclein, which are three IDPs implicated in Alzheimer's and Parkinson's diseases. The strategy described here offers novel opportunities for the identification of effective molecular scaffolds for drug discovery for neurodegenerative disorders and to provide insights into the mechanism of small-molecule binding to IDPs.
CRISPR library designer (CLD): software for multispecies design of single guide RNA libraries.

Science.gov (United States)

Heigwer, Florian; Zhan, Tianzuo; Breinig, Marco; Winter, Jan; Brügemann, Dirk; Leible, Svenja; Boutros, Michael

2016-03-24

Genetic screens using CRISPR/Cas9 are a powerful method for the functional analysis of genomes. Here we describe CRISPR library designer (CLD), an integrated bioinformatics application for the design of custom single guide RNA (sgRNA) libraries for all organisms with annotated genomes. CLD is suitable for the design of libraries using modified CRISPR enzymes and targeting non-coding regions. To demonstrate its utility, we perform a pooled screen for modulators of the TNF-related apoptosis inducing ligand (TRAIL) pathway using a custom library of 12,471 sgRNAs. CLD predicts a high fraction of functional sgRNAs and is publicly available at https://github.com/boutroslab/cld.
Academic Digital Library Construction Evaluation: Measures and Approaches

OpenAIRE

Wang , Qiyun

2008-01-01

Through review norms, standards and practice related to academic digital library construction evaluation at home and abroad, on the basis of investigation and study on the digital library evaluation at home and abroad, for status quo of the academic digital library construction, using qualitative analysis and quantitative analysis method, with methods and indicators for the traditional library evaluation system as a reference coordinates, put forward a comprehensive evaluation index system of...
America's Star Libraries, 2010: Top-Rated Libraries

Science.gov (United States)

Lyons, Ray; Lance, Keith Curry

2010-01-01

The "LJ" Index of Public Library Service 2010, "Library Journal"'s national rating of public libraries, identifies 258 "star" libraries. Created by Ray Lyons and Keith Curry Lance, and based on 2008 data from the IMLS, it rates 7,407 public libraries. The top libraries in each group get five, four, or three stars. All included libraries, stars or…
The Knuckle-Cracker's Dilemma: A Transaction Log Study of OPAC Subject Searching.

Science.gov (United States)

Ferl, Terry Ellen; Milsap, Larry

1996-01-01

Researchers studying subject searching distributed an online questionnaire to users who access the University of California's online public access catalog, MELVYL, from public access terminals in the libraries of the University of California at Santa Cruz. This article discusses the results of transaction log analysis, comparison of in-library and…
Featured Library: Parrish Library

OpenAIRE

Kirkwood, Hal P, Jr

2015-01-01

The Roland G. Parrish Library of Management & Economics is located within the Krannert School of Management at Purdue University. Between 2005 - 2007 work was completed on a white paper that focused on a student-centered vision for the Management & Economics Library. The next step was a massive collection reduction and a re-envisioning of both the services and space of the library. Thus began a 3 phase renovation from a 2 floor standard, collection-focused library into a single floor, 18,000s...
Protocol for an electrospray ionization tandem mass spectral product ion library: development and application for identification of 240 pesticides in foods.

Science.gov (United States)

Zhang, Kai; Wong, Jon W; Yang, Paul; Hayward, Douglas G; Sakuma, Takeo; Zou, Yunyun; Schreiber, André; Borton, Christopher; Nguyen, Tung-Vi; Kaushik, Banerjee; Oulkar, Dasharath

2012-07-03

Modern determination techniques for pesticides must yield identification quickly with high confidence for timely enforcement of tolerances. A protocol for the collection of liquid chromatography (LC) electrospray ionization (ESI)-quadruple linear ion trap (Q-LIT) mass spectrometry (MS) library spectra was developed. Following the protocol, an enhanced product ion (EPI) library of 240 pesticides was developed by use of spectra collected from two laboratories. A LC-Q-LIT-MS workflow using scheduled multiple reaction monitoring (sMRM) survey scan, information-dependent acquisition (IDA) triggered collection of EPI spectra, and library search was developed and tested to identify the 240 target pesticides in one single LC-Q-LIT MS analysis. By use of LC retention time, one sMRM survey scan transition, and a library search, 75-87% of the 240 pesticides were identified in a single LC/MS analysis at fortified concentrations of 10 ng/g in 18 different foods. A conventional approach with LC-MS/MS using two MRM transitions produced the same identifications and comparable quantitative results with the same incurred foods as the LC-Q-LIT using EPI library search, finding 1.2-49 ng/g of either carbaryl, carbendazim, fenbuconazole, propiconazole, or pyridaben in peaches; carbendazim, imazalil, terbutryn, and thiabendazole in oranges; terbutryn in salmon; and azoxystrobin in ginseng. Incurred broccoli, cabbage, and kale were screened with the same EPI library using three LC-Q-LIT and a LC-quadruple time-of-flight (Q-TOF) instruments. The library search identified azoxystrobin, cyprodinil, fludioxinil, imidacloprid, metalaxyl, spinosyn A, D, and J, amd spirotetramat with each instrument. The approach has a broad application in LC-MS/MS type targeted screening in food analysis.
The National Cryptologic Museum Library

Science.gov (United States)

2010-09-01

telegrams. Modern communications and encryption methods have made them obsolete and mainly of historical interest. The library is also home to a...interpretations. Cross References The National Cryptologic Museum Library Eugene Becker Last year, a widely published German technical author, Klaus...Schmeh, e-mailed the library of the National Cryptologic Museum from his home in Gelsenkirchen, Germany. He needed information for an article on the
Browsing Your Virtual Library: The Case of Expanding Universe.

Science.gov (United States)

Daniels, Wayne; Enright, Jeanne; Mackenzie, Scott

1997-01-01

Describes "Expanding Universe: a classified search tool for amateur astronomy," a Web site maintained by the Metropolitan Toronto Reference Library which uses a modified form of the Dewey Decimal Classification to organize a large file of astronomy hotlinks. Highlights include structure, HTML coding, design requirements, and future…
Best, Useful and Objective Precisions for Information Retrieval of Three Search Methods in PubMed and iPubMed

Directory of Open Access Journals (Sweden)

Somayyeh Nadi Ravandi

2016-10-01

Full Text Available MEDLINE is one of the valuable sources of medical information on the Internet. Among the different open access sites of MEDLINE, PubMed is the best-known site. In 2010, iPubMed was established with an interaction-fuzzy search method for MEDLINE access. In the present work, we aimed to compare the precision of the retrieved sources (Best, Useful and Objective precision in the PubMed and iPubMed using two search methods (simple and MeSH search in PubMed and interaction-fuzzy method in iPubmed. During our semi-empirical study period, we held training workshops for 61 students of higher education to teach them Simple Search, MeSH Search, and Fuzzy-Interaction Search methods. Then, the precision of 305 searches for each method prepared by the students was calculated on the basis of Best precision, Useful precision, and Objective precision formulas. Analyses were done in SPSS version 11.5 using the Friedman and Wilcoxon Test, and three precisions obtained with the three precision formulas were studied for the three search methods. The mean precision of the interaction-fuzzy Search method was higher than that of the simple search and MeSH search for all three types of precision, i.e., Best precision, Useful precision, and Objective precision, and the Simple search method was in the next rank, and their mean precisions were significantly different (P < 0.001. The precision of the interaction-fuzzy search method in iPubmed was investigated for the first time. Also for the first time, three types of precision were evaluated in PubMed and iPubmed. The results showed that the Interaction-Fuzzy search method is more precise than using the natural language search (simple search and MeSH search, and users of this method found papers that were more related to their queries; even though search in Pubmed is useful, it is important that users apply new search methods to obtain the best results.

The Marine Realms Information Bank family of digital libraries: access to free online information for coastal and marine science

Science.gov (United States)

Lightsom, Frances L.; Allwardt, Alan O.

2007-01-01

Searching the World Wide Web for reliable information about specific topics or locations can be frustrating: too many hits, too little relevance. A well-designed digital library, offering a carefully selected collection of online resources, is an attractive alternative to web search engines. The U.S. Geological Survey (USGS) provides three digital libraries for coastal and marine science to serve the needs of a diverse audience--scientists, public servants, educators, and the public.
CARL Corporation to Market Knight Ridder DIALOG Databases to the Academic and Public Library Market.

Science.gov (United States)

Machovec, George S.

1996-01-01

With the advent of CD-ROMs, libraries began to limit online searching via DIALOG. To increase DIALOG's market share, Colorado Alliance of Research Libraries (CARL) Corporation is developing graphical user interfaces using World Wide Web and Windows technology and has reached agreements with Knight Ridder Information and with most of their database…
Searching for truth: internet search patterns as a method of investigating online responses to a Russian illicit drug policy debate.

Science.gov (United States)

Zheluk, Andrey; Gillespie, James A; Quinn, Casey

2012-12-13

This is a methodological study investigating the online responses to a national debate over an important health and social problem in Russia. Russia is the largest Internet market in Europe, exceeding Germany in the absolute number of users. However, Russia is unusual in that the main search provider is not Google, but Yandex. This study had two main objectives. First, to validate Yandex search patterns against those provided by Google, and second, to test this method's adequacy for investigating online interest in a 2010 national debate over Russian illicit drug policy. We hoped to learn what search patterns and specific search terms could reveal about the relative importance and geographic distribution of interest in this debate. A national drug debate, centering on the anti-drug campaigner Egor Bychkov, was one of the main Russian domestic news events of 2010. Public interest in this episode was accompanied by increased Internet search. First, we measured the search patterns for 13 search terms related to the Bychkov episode and concurrent domestic events by extracting data from Google Insights for Search (GIFS) and Yandex WordStat (YaW). We conducted Spearman Rank Correlation of GIFS and YaW search data series. Second, we coded all 420 primary posts from Bychkov's personal blog between March 2010 and March 2012 to identify the main themes. Third, we compared GIFS and Yandex policies concerning the public release of search volume data. Finally, we established the relationship between salient drug issues and the Bychkov episode. We found a consistent pattern of strong to moderate positive correlations between Google and Yandex for the terms "Egor Bychkov" (r(s) = 0.88, P < .001), "Bychkov" (r(s) = .78, P < .001) and "Khimki"(r(s) = 0.92, P < .001). Peak search volumes for the Bychkov episode were comparable to other prominent domestic political events during 2010. Monthly search counts were 146,689 for "Bychkov" and 48,084 for "Egor Bychkov", compared to 53
Reflection on the talent structure of knowledge-service oriented nuclear technology library

International Nuclear Information System (INIS)

Zhang Xue; Zhang Ruiping

2010-01-01

Nuclear technology library is the only authoritative organization in collection of nuclear technology literatures.It has exceptional advantage and a large number of customers with great requirement. With promotion of network and digitization of information resource, new situation is posed before nuclear technology library-transforming from traditional library to knowledge-service oriented library. In order to carry on knowledge service effectively and conveniently, a variety of talents are essential. So establishing a talent team with high quality and complete specialities is the fundamental guarantee. Based on a great deal research and discussion, requirements for establishment of a talent team are put forward in the paper and suggestion are present: 5 basic specialized talents are required in nuclear technology library, including organization and management talent, basic operation talent, search service talent, technology application talent, information development talent. (authors)
Searching for cellular partners of hantaviral nonstructural protein NSs: Y2H screening of mouse cDNA library and analysis of cellular interactome.

Science.gov (United States)

Rönnberg, Tuomas; Jääskeläinen, Kirsi; Blot, Guillaume; Parviainen, Ville; Vaheri, Antti; Renkonen, Risto; Bouloy, Michele; Plyusnin, Alexander

2012-01-01

Hantaviruses (Bunyaviridae) are negative-strand RNA viruses with a tripartite genome. The small (S) segment encodes the nucleocapsid protein and, in some hantaviruses, also the nonstructural protein (NSs). The aim of this study was to find potential cellular partners for the hantaviral NSs protein. Toward this aim, yeast two-hybrid (Y2H) screening of mouse cDNA library was performed followed by a search for potential NSs protein counterparts via analyzing a cellular interactome. The resulting interaction network was shown to form logical, clustered structures. Furthermore, several potential binding partners for the NSs protein, for instance ACBD3, were identified and, to prove the principle, interaction between NSs and ACBD3 proteins was demonstrated biochemically.
Exploiting Chemical Libraries, Structure, and Genomics in the Search for Kinase Inhibitors

NARCIS (Netherlands)

Gray, Nathanael S.; Wodicka, Lisa; Thunnissen, Andy-Mark W.H.; Norman, Thea C.; Kwon, Soojin; Espinoza, F. Hernan; Morgan, David O.; Barnes, Georjana; LeClerc, Sophie; Meijer, Laurent; Kim, Sung-Hou; Lockhart, David J.; Schultz, Peter G.

1998-01-01

Selective protein kinase inhibitors were developed on the basis of the unexpected binding mode of 2,6,9-trisubstituted purines to the adenosine triphosphate-binding site of the human cyclin-dependent kinase 2 (CDK2). By iterating chemical library synthesis and biological screening, potent inhibitors
PIPERIDINE OLIGOMERS AND COMBINATORIAL LIBRARIES THEREOF

DEFF Research Database (Denmark)

1999-01-01

The present invention relates to piperidine oligomers, methods for the preparation of piperidine oligomers and compound libraries thereof, and the use of piperidine oligomers as drug substances. The present invention also relates to the use of combinatorial libraries of piperidine oligomers...... in libraries (arrays) of compounds especially suitable for screening purposes....
Using relational databases for improved sequence similarity searching and large-scale genomic analyses.

Science.gov (United States)

Mackey, Aaron J; Pearson, William R

2004-10-01

Relational databases are designed to integrate diverse types of information and manage large sets of search results, greatly simplifying genome-scale analyses. Relational databases are essential for management and analysis of large-scale sequence analyses, and can also be used to improve the statistical significance of similarity searches by focusing on subsets of sequence libraries most likely to contain homologs. This unit describes using relational databases to improve the efficiency of sequence similarity searching and to demonstrate various large-scale genomic analyses of homology-related data. This unit describes the installation and use of a simple protein sequence database, seqdb_demo, which is used as a basis for the other protocols. These include basic use of the database to generate a novel sequence library subset, how to extend and use seqdb_demo for the storage of sequence similarity search results and making use of various kinds of stored search results to address aspects of comparative genomic analysis.
Multigroup cross section library; WIMS library

International Nuclear Information System (INIS)

Kannan, Umasankari

2000-01-01

The WIMS library has been extensively used in thermal reactor calculations. This multigroup constants library was originally developed from the UKNDL in the late 60's and has been updated in 1986. This library has been distributed with the WIMS-D code by NEA data bank. The references to WIMS library in literature are the 'old' which is the original as developed by the AEA Winfrith and the 'new' which is the current 1986 WIMS library. IAEA has organised a CRP where a new and fully updated WIMS library will soon be available. This paper gives an overview of the definitions of the group constants that go into any basic nuclear data library used for reactor calculations. This paper also outlines the contents of the WIMS library and some of its shortcomings
A Polymerase Chain Reaction-Based Method for Isolating Clones from a Complimentary DNA Library in Sheep

Science.gov (United States)

Friis, Thor Einar; Stephenson, Sally; Xiao, Yin; Whitehead, Jon

2014-01-01

The sheep (Ovis aries) is favored by many musculoskeletal tissue engineering groups as a large animal model because of its docile temperament and ease of husbandry. The size and weight of sheep are comparable to humans, which allows for the use of implants and fixation devices used in human clinical practice. The construction of a complimentary DNA (cDNA) library can capture the expression of genes in both a tissue- and time-specific manner. cDNA libraries have been a consistent source of gene discovery ever since the technology became commonplace more than three decades ago. Here, we describe the construction of a cDNA library using cells derived from sheep bones based on the pBluescript cDNA kit. Thirty clones were picked at random and sequenced. This led to the identification of a novel gene, C12orf29, which our initial experiments indicate is involved in skeletal biology. We also describe a polymerase chain reaction-based cDNA clone isolation method that allows the isolation of genes of interest from a cDNA library pool. The techniques outlined here can be applied in-house by smaller tissue engineering groups to generate tools for biomolecular research for large preclinical animal studies and highlights the power of standard cDNA library protocols to uncover novel genes. PMID:24447069
Recursive deconvolution of combinatorial chemical libraries.

OpenAIRE

Erb, E; Janda, K D; Brenner, S

1994-01-01

A recursive strategy that solves for the active members of a chemical library is presented. A pentapeptide library with an alphabet of Gly, Leu, Phe, and Tyr (1024 members) was constructed on a solid support by the method of split synthesis. One member of this library (NH2-Tyr-Gly-Gly-Phe-Leu) is a native binder to a beta-endorphin antibody. A variation of the split synthesis approach is used to build the combinatorial library. In four vials, a member of the library's alphabet is coupled to a...
Arrangement and processing of monographic publications in youth sections of public libraries

Directory of Open Access Journals (Sweden)

Mateja Ločniškar-Fidler

2006-01-01

Full Text Available A systematic and transparent layout of library material on book shelves of public libraries is one of the essential conditions for successful viewing and searching of materials. The research tried to determine the contemporary classification system of library material for the youth. The data needed for the research was gathered and analyzed by a questionnaire completed by five randomly selected central public libraries. Special collections, arrangement and classification of certain fiction and specialized monographic publications for infants, teenagers and adolescents were analyzed. It was of our interest to observe whether the libraries assign the elements of a call number - which are evident on the library material and in online catalogs – according to standards and current instructions. The article also focuses on the unity and differences of the technical processing, and on color and/or image of labels which additionally explain the classification and the contents of the monographic publications for the youth.
The Alsos library for nuclear issues

International Nuclear Information System (INIS)

Settle, F.A.; Whaley, T.; Blackmer, E.

2005-01-01

Full text: This presentation will describe the content and features of the Alsos Digital Library for Nuclear Issues (http://alsos.wlu.edu). The library, funded by the U.S. National Science Foundation, provides a broad, balanced collection of indexed, annotated references for the study of nuclear issues ranging from nuclear reactors to Japanese poetry. All annotations have been reviewed by members of the library's prestigious National Advisory Board. The searchable collection includes books, articles, films, CD-ROMs, and websites. It currently contains approximately 1600 references and receives over 15000 visits per month. The mission of the library is to make the history and current status of nuclear issues more accessible and comprehensible to the general public as well as to students, educators, and other professionals in the many fields influenced by the forces of the nuclear age. References may be accessed by conventional keyword, creator, and title searches or by browsing topics under one of five categories; issues, warfare, science, people, and places. Of particular interest to conference participants are topics in the issues category that include nuclear power, terrorism, and nuclear waste. The library can also provide bibliographies for specific topics which can be embedded as hyperlinks on other websites which address of nuclear issues. Finally the Alsos Library is the bibliographical component of Nuclear Pathways (nuclearpathways.org), a composite site which is attempting to integrate websites dedicated to nuclear issues. The initial partner sites are: Atomic Archive (http://atomicarchive.com), Nuclear Chemistry in the Community (http://www.chemcases.com/2003version/nuclear/index2.htm), and Nuclear Files (http://nuclearfiles.org). (author)
Trends in hospital librarianship and hospital library services: 1989 to 2006.

Science.gov (United States)

Thibodeau, Patricia L; Funk, Carla J

2009-10-01

The research studied the status of hospital librarians and library services to better inform the Medical Library Association's advocacy activities. The Vital Pathways Survey Subcommittee of the Task Force on Vital Pathways for Hospital Librarians distributed a web-based survey to hospital librarians and academic health sciences library directors. The survey results were compared to data collected in a 1989 survey of hospital libraries by the American Hospital Association in order to identify any trends in hospital libraries, roles of librarians, and library services. A web-based hospital library report form based on the survey questions was also developed to more quickly identify changes in the status of hospital libraries on an ongoing basis. The greatest change in library services between 1989 and 2005/06 was in the area of access to information, with 40% more of the respondents providing access to commercial online services, 100% more providing access to Internet resources, and 28% more providing training in database searching and use of information resources. Twenty-nine percent (n = 587) of the 2005/06 respondents reported a decrease in staff over the last 5 years. Survey data support reported trends of consolidation of hospitals and hospital libraries and additions of new services. These services have likely required librarians to acquire new skills. It is hoped that future surveys will be undertaken to continue to study these trends.
The search for new amphiphiles: synthesis of a modular, high-throughput library

Directory of Open Access Journals (Sweden)

George C. Feast

2014-07-01

Full Text Available Amphiphilic compounds are used in a variety of applications due to their lyotropic liquid-crystalline phase formation, however only a limited number of compounds, in a potentially limitless field, are currently in use. A library of organic amphiphilic compounds was synthesised consisting of glucose, galactose, lactose, xylose and mannose head groups and double and triple-chain hydrophobic tails. A modular, high-throughput approach was developed, whereby head and tail components were conjugated using the copper-catalysed azide–alkyne cycloaddition (CuAAC reaction. The tails were synthesised from two core alkyne-tethered intermediates, which were subsequently functionalised with hydrocarbon chains varying in length and degree of unsaturation and branching, while the five sugar head groups were selected with ranging substitution patterns and anomeric linkages. A library of 80 amphiphiles was subsequently produced, using a 24-vial array, with the majority formed in very good to excellent yields. A preliminary assessment of the liquid-crystalline phase behaviour is also presented.
Preliminary exploration and thought of promoting library science Indigenization

International Nuclear Information System (INIS)

Liu Wenping; Du Jingling

2014-01-01

The article explains the significance of Library Science Indigenization, Answer some misunderstanding of Library Science Indigenization,reveals express form of Library Science Indigenization, Discusses criteria of Library Science Indigenization, finally give some suggestions and methods of Library Science Indigenization. (authors)
The Librarian Leading the Machine: A Reassessment of Library Instruction Methods

Science.gov (United States)

Greer, Katie; Hess, Amanda Nichols; Kraemer, Elizabeth W.

2016-01-01

This article builds on the 2007 College and Research Libraries article, "The Librarian, the Machine, or a Little of Both." Since that time, Oakland University Libraries implemented changes to its instruction program that reflect larger trends in teaching and assessment throughout the profession; following these revisions, librarians…
Factors Influencing Virtual Patron Satisfaction with Online Library Resources and Services

Directory of Open Access Journals (Sweden)

Katherine Tyler

2011-07-01

Full Text Available College students are accessing virtual libraries whether they are on campus or learning from a distance. Academic institutions serving virtual patrons must remain focused on meeting the needs of those library users by continually examining their preferences, their searching behavior, and the information they seek. The purpose of this research was to determine if virtual patrons are satisfied with the resources and services being provided by a university’s online library. Following a web-based survey, demographic characteristics of students were analyzed to determine if any influenced students’ satisfaction. Using analysis of variance, correlation, and descriptive statistics, several demographic factors were found to influence student satisfaction with the library’s online resources: age, gender, achieved educational level, student status, and computer experience. One factor, computer experience, was found to influence student satisfaction with the library’s online services. Overall, students reported satisfaction with the university’s online library resources and services. Comments submitted to open-ended questions regarding areas for improvement to the online library provide library administrators with avenues for development to increase awareness of library services, focus improvement in navigation, and enhance student satisfaction.
New Internet search volume-based weighting method for integrating various environmental impacts

Energy Technology Data Exchange (ETDEWEB)

Ji, Changyoon, E-mail: changyoon@yonsei.ac.kr; Hong, Taehoon, E-mail: hong7@yonsei.ac.kr

2016-01-15

Weighting is one of the steps in life cycle impact assessment that integrates various characterized environmental impacts as a single index. Weighting factors should be based on the society's preferences. However, most previous studies consider only the opinion of some people. Thus, this research proposes a new weighting method that determines the weighting factors of environmental impact categories by considering public opinion on environmental impacts using the Internet search volumes for relevant terms. To validate the new weighting method, the weighting factors for six environmental impacts calculated by the new weighting method were compared with the existing weighting factors. The resulting Pearson's correlation coefficient between the new and existing weighting factors was from 0.8743 to 0.9889. It turned out that the new weighting method presents reasonable weighting factors. It also requires less time and lower cost compared to existing methods and likewise meets the main requirements of weighting methods such as simplicity, transparency, and reproducibility. The new weighting method is expected to be a good alternative for determining the weighting factor. - Highlight: • A new weighting method using Internet search volume is proposed in this research. • The new weighting method reflects the public opinion using Internet search volume. • The correlation coefficient between new and existing weighting factors is over 0.87. • The new weighting method can present the reasonable weighting factors. • The proposed method can be a good alternative for determining the weighting factors.
New Internet search volume-based weighting method for integrating various environmental impacts

International Nuclear Information System (INIS)

Ji, Changyoon; Hong, Taehoon

2016-01-01

Weighting is one of the steps in life cycle impact assessment that integrates various characterized environmental impacts as a single index. Weighting factors should be based on the society's preferences. However, most previous studies consider only the opinion of some people. Thus, this research proposes a new weighting method that determines the weighting factors of environmental impact categories by considering public opinion on environmental impacts using the Internet search volumes for relevant terms. To validate the new weighting method, the weighting factors for six environmental impacts calculated by the new weighting method were compared with the existing weighting factors. The resulting Pearson's correlation coefficient between the new and existing weighting factors was from 0.8743 to 0.9889. It turned out that the new weighting method presents reasonable weighting factors. It also requires less time and lower cost compared to existing methods and likewise meets the main requirements of weighting methods such as simplicity, transparency, and reproducibility. The new weighting method is expected to be a good alternative for determining the weighting factor. - Highlight: • A new weighting method using Internet search volume is proposed in this research. • The new weighting method reflects the public opinion using Internet search volume. • The correlation coefficient between new and existing weighting factors is over 0.87. • The new weighting method can present the reasonable weighting factors. • The proposed method can be a good alternative for determining the weighting factors.

Tumor-targeting peptides from combinatorial libraries*

Science.gov (United States)

Liu, Ruiwu; Li, Xiaocen; Xiao, Wenwu; Lam, Kit S.

2018-01-01

Cancer is one of the major and leading causes of death worldwide. Two of the greatest challenges infighting cancer are early detection and effective treatments with no or minimum side effects. Widespread use of targeted therapies and molecular imaging in clinics requires high affinity, tumor-specific agents as effective targeting vehicles to deliver therapeutics and imaging probes to the primary or metastatic tumor sites. Combinatorial libraries such as phage-display and one-bead one-compound (OBOC) peptide libraries are powerful approaches in discovering tumor-targeting peptides. This review gives an overview of different combinatorial library technologies that have been used for the discovery of tumor-targeting peptides. Examples of tumor-targeting peptides identified from each combinatorial library method will be discussed. Published tumor-targeting peptide ligands and their applications will also be summarized by the combinatorial library methods and their corresponding binding receptors. PMID:27210583
Searching the ASRS Database Using QUORUM Keyword Search, Phrase Search, Phrase Generation, and Phrase Discovery

Science.gov (United States)

McGreevy, Michael W.; Connors, Mary M. (Technical Monitor)

2001-01-01

To support Search Requests and Quick Responses at the Aviation Safety Reporting System (ASRS), four new QUORUM methods have been developed: keyword search, phrase search, phrase generation, and phrase discovery. These methods build upon the core QUORUM methods of text analysis, modeling, and relevance-ranking. QUORUM keyword search retrieves ASRS incident narratives that contain one or more user-specified keywords in typical or selected contexts, and ranks the narratives on their relevance to the keywords in context. QUORUM phrase search retrieves narratives that contain one or more user-specified phrases, and ranks the narratives on their relevance to the phrases. QUORUM phrase generation produces a list of phrases from the ASRS database that contain a user-specified word or phrase. QUORUM phrase discovery finds phrases that are related to topics of interest. Phrase generation and phrase discovery are particularly useful for finding query phrases for input to QUORUM phrase search. The presentation of the new QUORUM methods includes: a brief review of the underlying core QUORUM methods; an overview of the new methods; numerous, concrete examples of ASRS database searches using the new methods; discussion of related methods; and, in the appendices, detailed descriptions of the new methods.
DNA-encoded chemical libraries: advancing beyond conventional small-molecule libraries.

Science.gov (United States)

Franzini, Raphael M; Neri, Dario; Scheuermann, Jörg

2014-04-15

DNA-encoded chemical libraries (DECLs) represent a promising tool in drug discovery. DECL technology allows the synthesis and screening of chemical libraries of unprecedented size at moderate costs. In analogy to phage-display technology, where large antibody libraries are displayed on the surface of filamentous phage and are genetically encoded in the phage genome, DECLs feature the display of individual small organic chemical moieties on DNA fragments serving as amplifiable identification barcodes. The DNA-tag facilitates the synthesis and allows the simultaneous screening of very large sets of compounds (up to billions of molecules), because the hit compounds can easily be identified and quantified by PCR-amplification of the DNA-barcode followed by high-throughput DNA sequencing. Several approaches have been used to generate DECLs, differing both in the methods used for library encoding and for the combinatorial assembly of chemical moieties. For example, DECLs can be used for fragment-based drug discovery, displaying a single molecule on DNA or two chemical moieties at the extremities of complementary DNA strands. DECLs can vary substantially in the chemical structures and the library size. While ultralarge libraries containing billions of compounds have been reported containing four or more sets of building blocks, also smaller libraries have been shown to be efficient for ligand discovery. In general, it has been found that the overall library size is a poor predictor for library performance and that the number and diversity of the building blocks are rather important indicators. Smaller libraries consisting of two to three sets of building blocks better fulfill the criteria of drug-likeness and often have higher quality. In this Account, we present advances in the DECL field from proof-of-principle studies to practical applications for drug discovery, both in industry and in academia. DECL technology can yield specific binders to a variety of target
Library 3.0 intelligent libraries and apomediation

CERN Document Server

Kwanya, Tom; Underwood, Peter

2015-01-01

The emerging generation of research and academic library users expect the delivery of user-centered information services. 'Apomediation' refers to the supporting role librarians can give users by stepping in when users need help. Library 3.0 explores the ongoing debates on the "point oh” phenomenon and its impact on service delivery in libraries. This title analyses Library 3.0 and its potential in creating intelligent libraries capable of meeting contemporary needs, and the growing role of librarians as apomediators. Library 3.0 is divided into four chapters. The first chapter introduces and places the topic in context. The second chapter considers "point oh” libraries. The third chapter covers library 3.0 librarianship, while the final chapter explores ways libraries can move towards '3.0'.
The search conference as a method in planning community health promotion actions

Directory of Open Access Journals (Sweden)

Eva Magnus

2016-08-01

Full Text Available Aims: The aim of this article is to describe and discuss how the search conference can be used as a method for planning health promotion actions in local communities. Design and methods: The article draws on experiences with using the method for an innovative project in health promotion in three Norwegian municipalities. The method is described both in general and how it was specifically adopted for the project. Results and conclusions: The search conference as a method was used to develop evidence-based health promotion action plans. With its use of both bottom-up and top-down approaches, this method is a relevant strategy for involving a community in the planning stages of health promotion actions in line with political expectations of participation, ownership, and evidence-based initiatives.
Croatian library leaders’ views on (their library quality

Directory of Open Access Journals (Sweden)

Kornelija Petr Balog

2014-04-01

Full Text Available The purpose of this paper is to determine and describe the library culture in Croatian public libraries. Semi-structured interviews with 14 library directors (ten public and four academic were conducted. The tentative discussion topics were: definition of quality, responsibility for quality, satisfaction with library services, familiarization with user perspective of library and librarians, monitoring of user expectations and opinions. These interviews incorporate some of the findings of the project Evaluation of library and information services: public and academic libraries. The project investigates library culture in Croatian public and academic libraries and their preparedness for activities of performance measurement. The interviews reveal that library culture has changed positively in the past few years and that library leaders have positive attitude towards quality and evaluation activities. Library culture in Croatian libraries is a relatively new concept and as such was not actively developed and/or created. This article looks into the library culture of Croatian libraries, but at the same time investigates whether there is any trace of culture of assessment in them. Also, this article brings the latest update on views, opinions and atmosphere in Croatian public and academic libraries.
Application of RSS in Special Libraries

OpenAIRE

Shima Moradi

2007-01-01

Despite of ever increasing scope and volume of online information content and the constant need for easy accessibility to these contents, experts in various subject matters always face time constraints when searching for information or looking up their intended resource. Meanwhile, special libraries are faced with diminishing resources, time and human resource needed for providing services and meeting the information need of the said experts. Nowadays Push Technologies, in form of RSS could b...
Dissemination of 3D Visualizations of Complex Function Data for the NIST Digital Library of Mathematical Functions

Directory of Open Access Journals (Sweden)

Qiming Wang

2007-03-01

Full Text Available The National Institute of Standards and Technology (NIST is developing a digital library to replace the widely used National Bureau of Standards Handbook of Mathematical Functions published in 1964. The NIST Digital Library of Mathematical Functions (DLMF will include formulas, methods of computation, references, and links to software for over forty functions. It will be published both in hardcopy format and as a website featuring interactive navigation, a mathematical equation search, 2D graphics, and dynamic interactive 3D visualizations. This paper focuses on the development and accessibility of the 3D visualizations for the digital library. We examine the techniques needed to produce accurate computations of function data, and through a careful evaluation of several prototypes, we address the advantages and disadvantages of using various technologies, including the Virtual Reality Modeling Language (VRML, interactive embedded graphics, and video capture to render and disseminate the visualizations in an environment accessible to users on various platforms.
Quantitative evaluation of recall and precision of CAT Crawler, a search engine specialized on retrieval of Critically Appraised Topics

Science.gov (United States)

Dong, Peng; Wong, Ling Ling; Ng, Sarah; Loh, Marie; Mondry, Adrian

2004-01-01

Background Critically Appraised Topics (CATs) are a useful tool that helps physicians to make clinical decisions as the healthcare moves towards the practice of Evidence-Based Medicine (EBM). The fast growing World Wide Web has provided a place for physicians to share their appraised topics online, but an increasing amount of time is needed to find a particular topic within such a rich repository. Methods A web-based application, namely the CAT Crawler, was developed by Singapore's Bioinformatics Institute to allow physicians to adequately access available appraised topics on the Internet. A meta-search engine, as the core component of the application, finds relevant topics following keyword input. The primary objective of the work presented here is to evaluate the quantity and quality of search results obtained from the meta-search engine of the CAT Crawler by comparing them with those obtained from two individual CAT search engines. From the CAT libraries at these two sites, all possible keywords were extracted using a keyword extractor. Of those common to both libraries, ten were randomly chosen for evaluation. All ten were submitted to the two search engines individually, and through the meta-search engine of the CAT Crawler. Search results were evaluated for relevance both by medical amateurs and professionals, and the respective recall and precision were calculated. Results While achieving an identical recall, the meta-search engine showed a precision of 77.26% (±14.45) compared to the individual search engines' 52.65% (±12.0) (p search engine approach. The improved precision due to inherent filters underlines the practical usefulness of this tool for clinicians. PMID:15588311
Search method for long-duration gravitational-wave transients from neutron stars

International Nuclear Information System (INIS)

Prix, R.; Giampanis, S.; Messenger, C.

2011-01-01

We introduce a search method for a new class of gravitational-wave signals, namely, long-duration O(hours-weeks) transients from spinning neutron stars. We discuss the astrophysical motivation from glitch relaxation models and we derive a rough estimate for the maximal expected signal strength based on the superfluid excess rotational energy. The transient signal model considered here extends the traditional class of infinite-duration continuous-wave signals by a finite start-time and duration. We derive a multidetector Bayes factor for these signals in Gaussian noise using F-statistic amplitude priors, which simplifies the detection statistic and allows for an efficient implementation. We consider both a fully coherent statistic, which is computationally limited to directed searches for known pulsars, and a cheaper semicoherent variant, suitable for wide parameter-space searches for transients from unknown neutron stars. We have tested our method by Monte-Carlo simulation, and we find that it outperforms orthodox maximum-likelihood approaches both in sensitivity and in parameter-estimation quality.
Implications of information technology on the training of library and ...

African Journals Online (AJOL)

Implications of information technology on the training of library and information science professionals in Nigeria: an analysis of the curricula of some selected ... Information Impact: Journal of Information and Knowledge Management. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives.
Assessment for One-Shot Library Instruction: A Conceptual Approach

Science.gov (United States)

Wang, Rui

2016-01-01

The purpose of this study is to explore a conceptual approach to assessment for one-shot library instruction. This study develops a new assessment instrument based on Carol Kuhlthau's information search process (ISP) model. The new instrument focuses on measuring and identifying changes in student readiness to do research along three…
Evaluation Framework for Search Instruments

International Nuclear Information System (INIS)

Warren, Glen A.; Smith, Leon E.; Cooper, Matt W.; Kaye, William R.

2005-01-01

A framework for quantitatively evaluating current and proposed gamma-ray search instrument designs has been developed. The framework is designed to generate a large library of ''virtual neighborhoods'' that can be used to test and evaluate nearly any gamma-ray sensor type. Calculating nuisance-source emissions and combining various sources to create a large number of random virtual scenes places a significant computational burden on the development of the framework. To reduce this burden, a number of radiation transport simplifications have been made which maintain the essential physics ingredients for the quantitative assessment of search instruments while significantly reducing computational times. The various components of the framework, from the simulation and benchmarking of nuisance source emissions to the computational engine for generating the gigabytes of simulated search scenes, are discussed
Hybrid Genetic Algorithm - Local Search Method for Ground-Water Management

Science.gov (United States)

Chiu, Y.; Nishikawa, T.; Martin, P.

2008-12-01

Ground-water management problems commonly are formulated as a mixed-integer, non-linear programming problem (MINLP). Relying only on conventional gradient-search methods to solve the management problem is computationally fast; however, the methods may become trapped in a local optimum. Global-optimization schemes can identify the global optimum, but the convergence is very slow when the optimal solution approaches the global optimum. In this study, we developed a hybrid optimization scheme, which includes a genetic algorithm and a gradient-search method, to solve the MINLP. The genetic algorithm identifies a near- optimal solution, and the gradient search uses the near optimum to identify the global optimum. Our methodology is applied to a conjunctive-use project in the Warren ground-water basin, California. Hi- Desert Water District (HDWD), the primary water-manager in the basin, plans to construct a wastewater treatment plant to reduce future septic-tank effluent from reaching the ground-water system. The treated wastewater instead will recharge the ground-water basin via percolation ponds as part of a larger conjunctive-use strategy, subject to State regulations (e.g. minimum distances and travel times). HDWD wishes to identify the least-cost conjunctive-use strategies that control ground-water levels, meet regulations, and identify new production-well locations. As formulated, the MINLP objective is to minimize water-delivery costs subject to constraints including pump capacities, available recharge water, water-supply demand, water-level constraints, and potential new-well locations. The methodology was demonstrated by an enumerative search of the entire feasible solution and comparing the optimum solution with results from the branch-and-bound algorithm. The results also indicate that the hybrid method identifies the global optimum within an affordable computation time. Sensitivity analyses, which include testing different recharge-rate scenarios, pond
Combining a Deconvolution and a Universal Library Search Algorithm for the Nontarget Analysis of Data-Independent Acquisition Mode Liquid Chromatography-High-Resolution Mass Spectrometry Results.

Science.gov (United States)

Samanipour, Saer; Reid, Malcolm J; Bæk, Kine; Thomas, Kevin V

2018-04-17

Nontarget analysis is considered one of the most comprehensive tools for the identification of unknown compounds in a complex sample analyzed via liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS). Due to the complexity of the data generated via LC-HRMS, the data-dependent acquisition mode, which produces the MS 2 spectra of a limited number of the precursor ions, has been one of the most common approaches used during nontarget screening. However, data-independent acquisition mode produces highly complex spectra that require proper deconvolution and library search algorithms. We have developed a deconvolution algorithm and a universal library search algorithm (ULSA) for the analysis of complex spectra generated via data-independent acquisition. These algorithms were validated and tested using both semisynthetic and real environmental data. A total of 6000 randomly selected spectra from MassBank were introduced across the total ion chromatograms of 15 sludge extracts at three levels of background complexity for the validation of the algorithms via semisynthetic data. The deconvolution algorithm successfully extracted more than 60% of the added ions in the analytical signal for 95% of processed spectra (i.e., 3 complexity levels multiplied by 6000 spectra). The ULSA ranked the correct spectra among the top three for more than 95% of cases. We further tested the algorithms with 5 wastewater effluent extracts for 59 artificial unknown analytes (i.e., their presence or absence was confirmed via target analysis). These algorithms did not produce any cases of false identifications while correctly identifying ∼70% of the total inquiries. The implications, capabilities, and the limitations of both algorithms are further discussed.
Parallel Computation on Multicore Processors Using Explicit Form of the Finite Element Method and C++ Standard Libraries

Directory of Open Access Journals (Sweden)

Rek Václav

2016-11-01

Full Text Available In this paper, the form of modifications of the existing sequential code written in C or C++ programming language for the calculation of various kind of structures using the explicit form of the Finite Element Method (Dynamic Relaxation Method, Explicit Dynamics in the NEXX system is introduced. The NEXX system is the core of engineering software NEXIS, Scia Engineer, RFEM and RENEX. It has the possibilities of multithreaded running, which can now be supported at the level of native C++ programming language using standard libraries. Thanks to the high degree of abstraction that a contemporary C++ programming language provides, a respective library created in this way can be very generalized for other purposes of usage of parallelism in computational mechanics.
Text mining for search term development in systematic reviewing: A discussion of some methods and challenges.

Science.gov (United States)

Stansfield, Claire; O'Mara-Eves, Alison; Thomas, James

2017-09-01

Using text mining to aid the development of database search strings for topics described by diverse terminology has potential benefits for systematic reviews; however, methods and tools for accomplishing this are poorly covered in the research methods literature. We briefly review the literature on applications of text mining for search term development for systematic reviewing. We found that the tools can be used in 5 overarching ways: improving the precision of searches; identifying search terms to improve search sensitivity; aiding the translation of search strategies across databases; searching and screening within an integrated system; and developing objectively derived search strategies. Using a case study and selected examples, we then reflect on the utility of certain technologies (term frequency-inverse document frequency and Termine, term frequency, and clustering) in improving the precision and sensitivity of searches. Challenges in using these tools are discussed. The utility of these tools is influenced by the different capabilities of the tools, the way the tools are used, and the text that is analysed. Increased awareness of how the tools perform facilitates the further development of methods for their use in systematic reviews. Copyright © 2017 John Wiley & Sons, Ltd.
Contributions to the History of Library Terminology.

Science.gov (United States)

Shapiro, Fred R.

1989-01-01

Discusses the historical method in lexicography, the general characteristics of library terminology, and the current state of library lexicography. Presents a glossary which lists quotations supplementing the coverage of library-related vocabulary in the "Oxford English Dictionary" (OED) and the "Dictionary of Americanisms"…
Search Strategy Development in a Flipped Library Classroom: A Student-Focused Assessment

Science.gov (United States)

Goates, Michael C.; Nelson, Gregory M.; Frost, Megan

2017-01-01

Librarians at Brigham Young University compared search statement development between traditional lecture and flipped instruction sessions. Students in lecture sessions scored significantly higher on developing search statements than those in flipped sessions. However, student evaluations show a strong preference for pedagogies that incorporate…
FRAGSION: ultra-fast protein fragment library generation by IOHMM sampling.

Science.gov (United States)

Bhattacharya, Debswapna; Adhikari, Badri; Li, Jilong; Cheng, Jianlin

2016-07-01

Speed, accuracy and robustness of building protein fragment library have important implications in de novo protein structure prediction since fragment-based methods are one of the most successful approaches in template-free modeling (FM). Majority of the existing fragment detection methods rely on database-driven search strategies to identify candidate fragments, which are inherently time-consuming and often hinder the possibility to locate longer fragments due to the limited sizes of databases. Also, it is difficult to alleviate the effect of noisy sequence-based predicted features such as secondary structures on the quality of fragment. Here, we present FRAGSION, a database-free method to efficiently generate protein fragment library by sampling from an Input-Output Hidden Markov Model. FRAGSION offers some unique features compared to existing approaches in that it (i) is lightning-fast, consuming only few seconds of CPU time to generate fragment library for a protein of typical length (300 residues); (ii) can generate dynamic-size fragments of any length (even for the whole protein sequence) and (iii) offers ways to handle noise in predicted secondary structure during fragment sampling. On a FM dataset from the most recent Critical Assessment of Structure Prediction, we demonstrate that FGRAGSION provides advantages over the state-of-the-art fragment picking protocol of ROSETTA suite by speeding up computation by several orders of magnitude while achieving comparable performance in fragment quality. Source code and executable versions of FRAGSION for Linux and MacOS is freely available to non-commercial users at http://sysbio.rnet.missouri.edu/FRAGSION/ It is bundled with a manual and example data. chengji@missouri.edu Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Single-tube library preparation for degraded DNA

DEFF Research Database (Denmark)

Carøe, Christian; Gopalakrishnan, Shyam; Vinner, Lasse

2018-01-01

these obstacles and enable higher throughput are therefore of interest to researchers working with degraded DNA. 2.In this study, we compare four Illumina library preparation protocols, including two “single-tube” methods developed for this study with the explicit aim of improving data quality and reducing...... of chemically damaged and highly fragmented DNA molecules. In particular, the enzymatic reactions and DNA purification steps during library preparation can result in DNA template loss and sequencing biases, affecting downstream analyses. The development of library preparation methods that circumvent...... preparation time and expenses. The methods are tested on grey wolf (Canis lupus) museum specimens. 3.We found single-tube protocols increase library complexity, yield more reads that map uniquely to the reference genome, reduce processing time, and may decrease laboratory costs by 90%. 4.Given the advantages...
Balancing Efficiency and Effectiveness for Fusion-Based Search Engines in the "Big Data" Environment

Science.gov (United States)

Li, Jieyu; Huang, Chunlan; Wang, Xiuhong; Wu, Shengli

2016-01-01

Introduction: In the big data age, we have to deal with a tremendous amount of information, which can be collected from various types of sources. For information search systems such as Web search engines or online digital libraries, the collection of documents becomes larger and larger. For some queries, an information search system needs to…
Library security better communication, safer facilities

CERN Document Server

Albrecht, Steve

2015-01-01

Through the methods outlined in this book, Albrecht demonstrates that effective communication not only makes library users feel more comfortable but also increases staff morale, ensuring the library is place where everyone feels welcome.
Search engines and the production of academic knowledge

OpenAIRE

van Dijck, J.

2010-01-01

This article argues that search engines in general, and Google Scholar in particular, have become significant co-producers of academic knowledge. Knowledge is not simply conveyed to users, but is co-produced by search engines’ ranking systems and profiling systems, none of which are open to the rules of transparency, relevance and privacy in a manner known from library scholarship in the public domain. Inexperienced users tend to trust proprietary engines as neutral mediators of knowledge and...
Cumulative query method for influenza surveillance using search engine data.

Science.gov (United States)

Seo, Dong-Woo; Jo, Min-Woo; Sohn, Chang Hwan; Shin, Soo-Yong; Lee, JaeHo; Yu, Maengsoo; Kim, Won Young; Lim, Kyoung Soo; Lee, Sang-Il

2014-12-16

Internet search queries have become an important data source in syndromic surveillance system. However, there is currently no syndromic surveillance system using Internet search query data in South Korea. The objective of this study was to examine correlations between our cumulative query method and national influenza surveillance data. Our study was based on the local search engine, Daum (approximately 25% market share), and influenza-like illness (ILI) data from the Korea Centers for Disease Control and Prevention. A quota sampling survey was conducted with 200 participants to obtain popular queries. We divided the study period into two sets: Set 1 (the 2009/10 epidemiological year for development set 1 and 2010/11 for validation set 1) and Set 2 (2010/11 for development Set 2 and 2011/12 for validation Set 2). Pearson's correlation coefficients were calculated between the Daum data and the ILI data for the development set. We selected the combined queries for which the correlation coefficients were .7 or higher and listed them in descending order. Then, we created a cumulative query method n representing the number of cumulative combined queries in descending order of the correlation coefficient. In validation set 1, 13 cumulative query methods were applied, and 8 had higher correlation coefficients (min=.916, max=.943) than that of the highest single combined query. Further, 11 of 13 cumulative query methods had an r value of ≥.7, but 4 of 13 combined queries had an r value of ≥.7. In validation set 2, 8 of 15 cumulative query methods showed higher correlation coefficients (min=.975, max=.987) than that of the highest single combined query. All 15 cumulative query methods had an r value of ≥.7, but 6 of 15 combined queries had an r value of ≥.7. Cumulative query method showed relatively higher correlation with national influenza surveillance data than combined queries in the development and validation set.
AUTOMATION BASED LIBRARY MANAGEMENT IN DEPOK PUBLIC LIBRARY IN THE CONTEXT OF RITUAL PERFORMANCE

Directory of Open Access Journals (Sweden)

Rafiqa Maulidia

2017-06-01

Full Text Available Library management using manual system is no longer adequate to handle the workload in the library routines, librarians must use application of library automation. To provide a good working performance, librarians use strategy, competences and certain habits, which are referred to as a ritual performance. The performance of the ritual is the demonstration of competence spontaneously by individuals in dealing with individuals, groups and organizations, which contains elements of personal ritual, the work ritual, social ritual, and organization ritual. The research focuses in the automation based library management in the context of the performance of the ritual. This study used a qualitative approach with case study method. The findings suggest that the personal ritual shows the personal habits of librarians to do their tasks, ritual librarian's work show responsibility towards their duties, social rituals strengthen the emotional connection between librarians and leaders, as well as ritual organizations suggest the involvement of librarians in giving their contribution in decision making. Conclusions of this study shows that the performance of rituals librarian at Depok Public Library gives librarians the skills to implement automation systems in the library management, and reflect the values of responsibility, mutual trust, and mutual respect. Key words : Library Management, Library Automation, Ritual Performance, Ritual Performance Value
How to Implement a New Search System and Make Friends While Doing It!

Science.gov (United States)

Powers, Michelle M.; Contreras, Rhonda

2013-01-01

What could bring more change to an online library than going from a federated to a discovery search system? Not much! This paper will share what was learned about initiating and implementing an important change that ultimately impacts a variety of stakeholders, and the importance of collaboration between library personnel at all levels of an…
Nuclide radioactive decay data uncertainties library

International Nuclear Information System (INIS)

Barabanova, D S; Zherdev, G M

2017-01-01

The results of the developing the library of uncertainties of radioactive decay data in the ABBN data library format are described. Different evaluations of uncertainties were compared and their effects on the results of calculations of residual energy release were determined using the test problems and experiment. Tables were generated in the ABBN format with the data obtained on the basis of libraries in ENDF-6 format. 3821 isotopes from the ENDF/B-7 data library, 3852 isotopes from the JEFF-3.11 data library and 1264 isotopes from the JENDL-4.0 data library were processed. It was revealed that the differences in the evaluations accepted in different decay data libraries are not so big, although they sometimes exceed the uncertainties assigned to the data in the ENDF/B-7 and JEFF-3.11 libraries, which as a rule, they agree with each other. On the basis of developed method it is supposed to create a library of data uncertainties for radioactive decay within the constant data system in FSUE RFNC-VNIIEF with its further connection with CRYSTAL module. (paper)
A Multi-Discipline, Multi-Genre Digital Library for Research and Education

Science.gov (United States)

Nelson, Michael L.; Maly, Kurt; Shen, Stewart N. T.

2004-01-01

We describe NCSTRL+, a unified, canonical digital library for educational and scientific and technical information (STI). NCSTRL+ is based on the Networked Computer Science Technical Report Library (NCSTRL), a World Wide Web (WWW) accessible digital library (DL) that provides access to over 100 university departments and laboratories. NCSTRL+ implements two new technologies: cluster functionality and publishing "buckets". We have extended the Dienst protocol, the protocol underlying NCSTRL, to provide the ability to "cluster" independent collections into a logically centralized digital library based upon subject category classification, type of organization, and genres of material. The concept of "buckets" provides a mechanism for publishing and managing logically linked entities with multiple data formats. The NCSTRL+ prototype DL contains the holdings of NCSTRL and the NASA Technical Report Server (NTRS). The prototype demonstrates the feasibility of publishing into a multi-cluster DL, searching across clusters, and storing and presenting buckets of information.
Library and Information Science's Ontological Position in the Networked Society: Using New Technology to Get Back to an Old Practice

Science.gov (United States)

Kåhre, Peter

2013-01-01

Introduction: This paper concerns the ontological position of library and informations science in the networked society. The aim of the study is to understand library use and library functions in the age of Internet and artificial intelligent programmed search engines. Theoretical approach: The approach discusses so called sociocognitive tools in…
A fast tomographic method for searching the minimum free energy path

International Nuclear Information System (INIS)

Chen, Changjun; Huang, Yanzhao; Xiao, Yi; Jiang, Xuewei

2014-01-01

Minimum Free Energy Path (MFEP) provides a lot of important information about the chemical reactions, like the free energy barrier, the location of the transition state, and the relative stability between reactant and product. With MFEP, one can study the mechanisms of the reaction in an efficient way. Due to a large number of degrees of freedom, searching the MFEP is a very time-consuming process. Here, we present a fast tomographic method to perform the search. Our approach first calculates the free energy surfaces in a sequence of hyperplanes perpendicular to a transition path. Based on an objective function and the free energy gradient, the transition path is optimized in the collective variable space iteratively. Applications of the present method to model systems show that our method is practical. It can be an alternative approach for finding the state-to-state MFEP
Analysis of a Bibliographic Database Enhanced with a Library Classification.

Science.gov (United States)

Drabenstott, Karen Markey; And Others

1990-01-01

Describes a project that examined the effects of incorporating subject terms from the Dewey Decimal Classification (DDC) into a bibliographic database. It is concluded that the incorporation of DDC and possibly other library classifications into online catalogs can enhance subject access and provide additional subject searching strategies. (11…
The Recognition of Depreciation of Library Materials.

Science.gov (United States)

Carpenter, Michael; Millican, Rita

1991-01-01

Discussion of the depreciation of assets for nonprofit organizations focuses on a study conducted at the Louisiana State University Law Library to determine the cost basis for depreciation of library materials. Determining the useful life of the library materials is described and various methods of depreciation are explained. (five references)…
Financing the Electronic Library: Models and Options.

Science.gov (United States)

Waters, Richard L.; Kralisz, Victor Frank

1981-01-01

Places the cost considerations associated with public library automation in a framework of public finance comfortable to most administrators, discusses the importance of experience with use patterns in the electronic library in opening up new and innovative financing methods, and stresses the role of the library in the information industry. (JL)
Evaluation of the quality of the college library websites in Iranian medical Universities based on the Stover model.

Science.gov (United States)

Nasajpour, Mohammad Reza; Ashrafi-Rizi, Hasan; Soleymani, Mohammad Reza; Shahrzadi, Leila; Hassanzadeh, Akbar

2014-01-01

Today, the websites of college and university libraries play an important role in providing the necessary services for clients. These websites not only allow the users to access different collections of library resources, but also provide them with the necessary guidance in order to use the information. The goal of this study is the quality evaluation of the college library websites in Iranian Medical Universities based on the Stover model. This study uses an analytical survey method and is an applied study. The data gathering tool is the standard checklist provided by Stover, which was modified by the researchers for this study. The statistical population is the college library websites of the Iranian Medical Universities (146 websites) and census method was used for investigation. The data gathering method was a direct access to each website and filling of the checklist was based on the researchers' observations. Descriptive and analytical statistics (Analysis of Variance (ANOVA)) were used for data analysis with the help of the SPSS software. The findings showed that in the dimension of the quality of contents, the highest average belonged to type one universities (46.2%) and the lowest average belonged to type three universities (24.8%). In the search and research capabilities, the highest average belonged to type one universities (48.2%) and the lowest average belonged to type three universities. In the dimension of facilities provided for the users, type one universities again had the highest average (37.2%), while type three universities had the lowest average (15%). In general the library websites of type one universities had the highest quality (44.2%), while type three universities had the lowest quality (21.1%). Also the library websites of the College of Rehabilitation and the College of Paramedics, of the Shiraz University of Medical Science, had the highest quality scores. The results showed that there was a meaningful difference between the quality
An in silico MS/MS library for automatic annotation of novel FAHFA lipids.

Science.gov (United States)

Ma, Yan; Kind, Tobias; Vaniya, Arpana; Gennity, Ingrid; Fahrmann, Johannes F; Fiehn, Oliver

2015-01-01

with NIST MS Search or PepSearch software. The developing template is provided for advanced users to modify the parameters and export customized libraries according to their instrument features. Graphical abstractExample of experimental and in silico MS/MS spectra for FAHFA lipids.
Organic Contaminants Library for the Sample Analysis at Mars

Science.gov (United States)

Misra, P.; Garcia-Sanchez, R.; Canham, J.; Mahaffy, P. R.

2012-12-01

A library containing mass spectra for Sample Analysis at Mars (SAM) materials has been developed with the purpose of contamination identification and control. Based on analysis of the Gas Chromatography-Mass Spectrometric (GCMS) data through thermal desorption, organic compounds were successfully identified from material samples, such as polymers, paints and adhesives. The library contains the spectra for all the compounds found in each of these analyzed files and is supplemented by a file information spreadsheet, a spreadsheet-formatted library for easy searching, and a Perfluorotributylamine (PFTBA) based normalization protocol to make corrections to SAM data in order to meet the standard set by commercial libraries. An example of the library in use can be seen in Figure 1, where the abundances match closely, the spectral shape is retained, and the library picks up on it with an 88% identification probability. Of course, there are also compounds that have not been identified and are retained as unknowns. The library we have developed, along with its supplemental materials, is useful from both organizational and practical viewpoints. Through them we are able to organize large volumes of GCMS data, while at the same time breaking down the components that each material sample is made of. This approach in turn allows us straightforward and fast access to information that will be critical while performing analysis on the data recorded by the SAM instrumentation. In addition, the normalization protocol dramatically increased the identification probability. In SAM GCMS, PFTBA signals were obfuscated, resulting in library matches far away from PFTBA; by using the normalization protocol we were able to transform it into a 92% probable spectral match for PFTBA. The project has demonstrated conclusively that the library is successful in identifying unknown compounds utilizing both the Automated Mass Spectral Deconvolution & Identification System (AMDIS) and the Ion
A Survey of Internet Access and Use by Students of Library and ...

African Journals Online (AJOL)

A Survey of Internet Access and Use by Students of Library and Information Science ... access and utilize Internet facilities, level of search skills, reasons for use of Internet, ... Data collected for the study was analyzed using descriptive statistics.
The Electronic Library of the Thermal Physical Databases

International Nuclear Information System (INIS)

Zhuravleva, Y.; Mingaleeva, G.; Mokrousov, K.; Yashnikov, D.

2008-01-01

base library collect experimental data-base not only for verification of one-dimensional thermal hydraulic system codes with average flow parameters but also include data useful for the subchannel thermal hydraulic analyses in rod bundles We update the library regularly. Now the library contains the following bases: critical heat flux databank (10000 experimental points, 136 test sections, 57 sourses); post-crisis heat transfer; void fraction in vertical pipes and rod bundles; critical flow from pipes, valves and flow limiters; heat transfer to supercritical water; local thermal hydraulic parameters in fuel rod assemblies; transient processes on test sites and nuclear power plants. MS Access was used for the creation of the library. The experiment description and results are saved in MS Word and Excel formats correspondently. The basic principles of the library are: the regular updating of the library; the searching and choosing data by user's specify parameters; the simple data processing; the information in each databank must be efficient both for traditional analyses methods and new approaches.(author)
Digital Libraries: The Challenge of Integrating Instagram with a Taxonomy for Content Management

Directory of Open Access Journals (Sweden)

Simona Ibba

2016-05-01

Full Text Available Interoperability and social implication are two current challenges in the digital library (DL context. To resolve the problem of interoperability, our work aims to find a relationship between the main metadata schemas. In particular, we want to formalize knowledge through the creation of a metadata taxonomy built with the analysis and the integration of existing schemas associated with DLs. We developed a method to integrate and combine Instagram metadata and hashtags. The final result is a taxonomy, which provides innovative metadata with respect to the classification of resources, as images of Instagram and the user-generated content, that play a primary role in the context of modern DLs. The possibility of Instagram to localize the photos inserted by users allows us to interpret the most relevant and interesting informative content for a specific user type and in a specific location and to improve access, visibility and searching of library content.

Academic medical center libraries on the Web.

Science.gov (United States)

Tannery, N H; Wessel, C B

1998-10-01

Academic medical center libraries are moving towards publishing electronically, utilizing networked technologies, and creating digital libraries. The catalyst for this movement has been the Web. An analysis of academic medical center library Web pages was undertaken to assess the information created and communicated in early 1997. A summary of present uses and suggestions for future applications is provided. A method for evaluating and describing the content of library Web sites was designed. The evaluation included categorizing basic information such as description and access to library services, access to commercial databases, and use of interactive forms. The main goal of the evaluation was to assess original resources produced by these libraries.
Chemical Space of DNA-Encoded Libraries.

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Franzini, Raphael M; Randolph, Cassie

2016-07-28

In recent years, DNA-encoded chemical libraries (DECLs) have attracted considerable attention as a potential discovery tool in drug development. Screening encoded libraries may offer advantages over conventional hit discovery approaches and has the potential to complement such methods in pharmaceutical research. As a result of the increased application of encoded libraries in drug discovery, a growing number of hit compounds are emerging in scientific literature. In this review we evaluate reported encoded library-derived structures and identify general trends of these compounds in relation to library design parameters. We in particular emphasize the combinatorial nature of these libraries. Generally, the reported molecules demonstrate the ability of this technology to afford hits suitable for further lead development, and on the basis of them, we derive guidelines for DECL design.
Libraries for users services in academic libraries

CERN Document Server

Alvite, Luisa

2010-01-01

This book reviews the quality and evolution of academic library services. It revises service trends offered by academic libraries and the challenge of enhancing traditional ones such as: catalogues, repositories and digital collections, learning resources centres, virtual reference services, information literacy and 2.0 tools.studies the role of the university library in the new educational environment of higher educationrethinks libraries in academic contextredefines roles for academic libraries
NEIC Library Services

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The National Enforcement Investigation Center (NEIC) Environmental Forensic Library partners with NEIC's forensic scientists to retrieve, validate and deliver information to develop methods, defensible regulations, and environmental measurements.
Without Library Resources and Services, the Scholarly Activity of Medical Faculty and Residents Would Register a Code Blue

Directory of Open Access Journals (Sweden)

Kathleen Reed

2017-03-01

Full Text Available A Review of: Quesenberry, A. C., Oelschlegel, S., Earl, M., Leonard, K., & Vaughn, C. J. (2016. The impact of library resources and services on the scholarly activity of medical faculty and residents. Medical Reference Services Quarterly, 35(3, 259-265. http://dx.doi:org/10.1080/02763869.2016.1189778 Objective – This study aimed to determine the use of three library services – literature search service, article delivery service, and library resources – among medical faculty and residents with regard to scholarly activity. Design – Survey. Setting – Medical Library and Health Information Centre at a large university in the United States of America. Subjects – 65 medical faculty and residents. Methods – The authors sent out 433 invitations to participate in a 23-question survey via an email distribution list. A total of 65 individuals participated, for a response rate of 15%. Questions related to the use of library services for scholarly activity, patterns of information-seeking behaviour, and instructional needs. Comments were allowed on several questions, and a final open-ended question was included. Main Results – All respondents used PubMed at least a few times a year, with 71% selecting it as their first choice to search for articles. Only 20% prioritized Google or Google Scholar above PubMed as the first place to begin a search. The most popular reasons for using library resources were “lectures, papers, research, and patient care” (p.262. The first three of these activities are types of scholarly activity. Of the 65 respondents, 46% published article(s or book chapter(s. Within this group of authors, 67% of residents undertaking scholarly activity requested a literature review, 100% accessed online material themselves, and 67% requested articles. Faculty placed similar importance on these services, with 71% having requested a literature review, 87% having accessed materials themselves, and 75% having requested articles
Between the Sheets: a Library-wide Inventory with Google

Directory of Open Access Journals (Sweden)

Craig Boman

2017-10-01

Full Text Available When it comes to taking an inventory of physical items, libraries often rely on their traditional integrated library system’s (ILS à la carte add ons; outside vendors; or other possibly outdated, complex, and often expensive methods. For libraries with shrinking budgets and other limited resources, high costs can put these methods out of reach. At the University of Dayton Libraries, we set out to develop an inexpensive and reasonably easy-to-use method for conducting a library-wide physical item inventory. In this article, we explain a custom built Google Sheets-based library inventory system, along with some code for the implementation of a RESTful API (written in PHP that interacts with our ILS. We will also explain our use of Google Apps scripts in our Google Sheet, which are crucial to our systems. Although this method used a specific ILS (Innovative Interfaces' Sierra product and custom-built RESTful APIs, it may be possible to use similar approaches with other ILS software. Additional notes include areas for improvement and recommendations for interoperability with other ILS systems.
Quantitative evaluation of recall and precision of CAT Crawler, a search engine specialized on retrieval of Critically Appraised Topics

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Loh Marie

2004-12-01

Full Text Available Abstract Background Critically Appraised Topics (CATs are a useful tool that helps physicians to make clinical decisions as the healthcare moves towards the practice of Evidence-Based Medicine (EBM. The fast growing World Wide Web has provided a place for physicians to share their appraised topics online, but an increasing amount of time is needed to find a particular topic within such a rich repository. Methods A web-based application, namely the CAT Crawler, was developed by Singapore's Bioinformatics Institute to allow physicians to adequately access available appraised topics on the Internet. A meta-search engine, as the core component of the application, finds relevant topics following keyword input. The primary objective of the work presented here is to evaluate the quantity and quality of search results obtained from the meta-search engine of the CAT Crawler by comparing them with those obtained from two individual CAT search engines. From the CAT libraries at these two sites, all possible keywords were extracted using a keyword extractor. Of those common to both libraries, ten were randomly chosen for evaluation. All ten were submitted to the two search engines individually, and through the meta-search engine of the CAT Crawler. Search results were evaluated for relevance both by medical amateurs and professionals, and the respective recall and precision were calculated. Results While achieving an identical recall, the meta-search engine showed a precision of 77.26% (±14.45 compared to the individual search engines' 52.65% (±12.0 (p Conclusion The results demonstrate the validity of the CAT Crawler meta-search engine approach. The improved precision due to inherent filters underlines the practical usefulness of this tool for clinicians.
User Practices in Keyword and Boolean Searching on an Online Public Access Catalog.

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Ensor, Pat

1992-01-01

Discussion of keyword and Boolean searching techniques in online public access catalogs (OPACs) focuses on a study conducted at Indiana State University that examined users' attitudes toward searching on NOTIS (Northwestern Online Total Integrated System). Relevant literature is reviewed, and implications for library instruction are suggested. (17…
Geometrical Fuzzy Search Method for the Business Information Security Systems

Directory of Open Access Journals (Sweden)

Grigory Grigorievich Novikov

2014-12-01

Full Text Available The main reason of the article is how to use one of new fuzzy search method for information security of business or some other purposes. So many sensitive information leaks are through non-classified documents legal publishing. That’s why many intelligence services like to use the “mosaic” information collection method so much: This article is about how to prevent it.
Rapid and Robust Cross-Correlation-Based Seismic Phase Identification Using an Approximate Nearest Neighbor Method

Science.gov (United States)

Tibi, R.; Young, C. J.; Gonzales, A.; Ballard, S.; Encarnacao, A. V.

2016-12-01

The matched filtering technique involving the cross-correlation of a waveform of interest with archived signals from a template library has proven to be a powerful tool for detecting events in regions with repeating seismicity. However, waveform correlation is computationally expensive, and therefore impractical for large template sets unless dedicated distributed computing hardware and software are used. In this study, we introduce an Approximate Nearest Neighbor (ANN) approach that enables the use of very large template libraries for waveform correlation without requiring a complex distributed computing system. Our method begins with a projection into a reduced dimensionality space based on correlation with a randomized subset of the full template archive. Searching for a specified number of nearest neighbors is accomplished by using randomized K-dimensional trees. We used the approach to search for matches to each of 2700 analyst-reviewed signal detections reported for May 2010 for the IMS station MKAR. The template library in this case consists of a dataset of more than 200,000 analyst-reviewed signal detections for the same station from 2002-2014 (excluding May 2010). Of these signal detections, 60% are teleseismic first P, and 15% regional phases (Pn, Pg, Sn, and Lg). The analyses performed on a standard desktop computer shows that the proposed approach performs the search of the large template libraries about 20 times faster than the standard full linear search, while achieving recall rates greater than 80%, with the recall rate increasing for higher correlation values. To decide whether to confirm a match, we use a hybrid method involving a cluster approach for queries with two or more matches, and correlation score for single matches. Of the signal detections that passed our confirmation process, 52% were teleseismic first P, and 30% were regional phases.
Fast optimization of binary clusters using a novel dynamic lattice searching method

International Nuclear Information System (INIS)

Wu, Xia; Cheng, Wen

2014-01-01

Global optimization of binary clusters has been a difficult task despite of much effort and many efficient methods. Directing toward two types of elements (i.e., homotop problem) in binary clusters, two classes of virtual dynamic lattices are constructed and a modified dynamic lattice searching (DLS) method, i.e., binary DLS (BDLS) method, is developed. However, it was found that the BDLS can only be utilized for the optimization of binary clusters with small sizes because homotop problem is hard to be solved without atomic exchange operation. Therefore, the iterated local search (ILS) method is adopted to solve homotop problem and an efficient method based on the BDLS method and ILS, named as BDLS-ILS, is presented for global optimization of binary clusters. In order to assess the efficiency of the proposed method, binary Lennard-Jones clusters with up to 100 atoms are investigated. Results show that the method is proved to be efficient. Furthermore, the BDLS-ILS method is also adopted to study the geometrical structures of (AuPd) 79 clusters with DFT-fit parameters of Gupta potential
Synthesis and screening of peptide libraries with free C-termini.

Science.gov (United States)

Wang, Yen-Chih; Distefano, Mark D

2014-01-01

Peptide libraries are useful tools to investigate the relationship between structure and function of proteins. The creation of peptide libraries with free C-termini presents unique synthetic challenges. In this review, methods for creating peptide libraries using either solid-phase peptide synthesis or phage display are described. Methods for screening such libraries and their application in studying several important biological problems are also reported.
A New Model and Its Implementation of Academic Resources Services for Academic Libraries

Directory of Open Access Journals (Sweden)

Yu-Ting Chiang

2006-12-01

Full Text Available Internet has become one of the important channels for retrieval of academic resources in the recent years. The roles and service models of academic libraries has been changed accordingly. Most academic libraries have been providing subject directory (subject gateway for users to browse the highly selected academic resources. On the contrary, few academic libraries managed to provide academic resources for user to retrieve. This article proposes a new model which the libraries will cooperate with search engine providers to support the full-text retrieval for academic resources in a low cost. We discuss the design and implementation of “NTU Scholars Gateway” based on the new model. In addition, the functionalities and future development of NTU Scholars Gateway are discussedas well. [Article content in Chinese
Active Search on Carcasses versus Pitfall Traps: a Comparison of Sampling Methods.

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Zanetti, N I; Camina, R; Visciarelli, E C; Centeno, N D

2016-04-01

The study of insect succession in cadavers and the classification of arthropods have mostly been done by placing a carcass in a cage, protected from vertebrate scavengers, which is then visited periodically. An alternative is to use specific traps. Few studies on carrion ecology and forensic entomology involving the carcasses of large vertebrates have employed pitfall traps. The aims of this study were to compare both sampling methods (active search on a carcass and pitfall trapping) for each coleopteran family, and to establish whether there is a discrepancy (underestimation and/or overestimation) in the presence of each family by either method. A great discrepancy was found for almost all families with some of them being more abundant in samples obtained through active search on carcasses and others in samples from traps, whereas two families did not show any bias towards a given sampling method. The fact that families may be underestimated or overestimated by the type of sampling technique highlights the importance of combining both methods, active search on carcasses and pitfall traps, in order to obtain more complete information on decomposition, carrion habitat and cadaveric families or species. Furthermore, a hypothesis advanced on the reasons for the underestimation by either sampling method showing biases towards certain families. Information about the sampling techniques indicating which would be more appropriate to detect or find a particular family is provided.
Winds of change: research libraries

DEFF Research Database (Denmark)

Bang, Tove; Harbo, Karen

2002-01-01

The article takes its starting point in new trends and paradigm shifts in scholarly research methods and discusses how research libraries must act in relation to this. Various innovative initiatives at LASB are described, especially within the areas of electronic dissemination and presentation...... at ASB and a software company. LASB is positive towards and will continue working with this method. Finally the investment in future library services is discussed and a tangible offer is put into perspective: electronic reference services...
A cost-effective method for Illumina small RNA-Seq library preparation using T4 RNA ligase 1 adenylated adapters

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Chen Yun-Ru

2012-09-01

Full Text Available Abstract Background Deep sequencing is a powerful tool for novel small RNA discovery. Illumina small RNA sequencing library preparation requires a pre-adenylated 3’ end adapter containing a 5’,5’-adenyl pyrophosphoryl moiety. In the absence of ATP, this adapter can be ligated to the 3’ hydroxyl group of small RNA, while RNA self-ligation and concatenation are repressed. Pre-adenylated adapters are one of the most essential and costly components required for library preparation, and few are commercially available. Results We demonstrate that DNA oligo with 5’ phosphate and 3’ amine groups can be enzymatically adenylated by T4 RNA ligase 1 to generate customized pre-adenylated adapters. We have constructed and sequenced a small RNA library for tomato (Solanum lycopersicum using the T4 RNA ligase 1 adenylated adapter. Conclusion We provide an efficient and low-cost method for small RNA sequencing library preparation, which takes two days to complete and costs around $20 per library. This protocol has been tested in several plant species for small RNA sequencing including sweet potato, pepper, watermelon, and cowpea, and could be readily applied to any RNA samples.
Low-Mode Conformational Search Method with Semiempirical Quantum Mechanical Calculations: Application to Enantioselective Organocatalysis.

Science.gov (United States)

Kamachi, Takashi; Yoshizawa, Kazunari

2016-02-22

A conformational search program for finding low-energy conformations of large noncovalent complexes has been developed. A quantitatively reliable semiempirical quantum mechanical PM6-DH+ method, which is able to accurately describe noncovalent interactions at a low computational cost, was employed in contrast to conventional conformational search programs in which molecular mechanical methods are usually adopted. Our approach is based on the low-mode method whereby an initial structure is perturbed along one of its low-mode eigenvectors to generate new conformations. This method was applied to determine the most stable conformation of transition state for enantioselective alkylation by the Maruoka and cinchona alkaloid catalysts and Hantzsch ester hydrogenation of imines by chiral phosphoric acid. Besides successfully reproducing the previously reported most stable DFT conformations, the conformational search with the semiempirical quantum mechanical calculations newly discovered a more stable conformation at a low computational cost.
Comparison of several chemometric methods of libraries and classifiers for the analysis of expired drugs based on Raman spectra.

Science.gov (United States)

Gao, Qun; Liu, Yan; Li, Hao; Chen, Hui; Chai, Yifeng; Lu, Feng

2014-06-01

Some expired drugs are difficult to detect by conventional means. If they are repackaged and sold back into market, they will constitute a new public health challenge. For the detection of repackaged expired drugs within specification, paracetamol tablet from a manufacturer was used as a model drug in this study for comparison of Raman spectra-based library verification and classification methods. Raman spectra of different batches of paracetamol tablets were collected and a library including standard spectra of unexpired batches of tablets was established. The Raman spectrum of each sample was identified by cosine and correlation with the standard spectrum. The average HQI of the suspicious samples and the standard spectrum were calculated. The optimum threshold values were 0.997 and 0.998 respectively as a result of ROC and four evaluations, for which the accuracy was up to 97%. Three supervised classifiers, PLS-DA, SVM and k-NN, were chosen to establish two-class classification models and compared subsequently. They were used to establish a classification of expired batches and an unexpired batch, and predict the suspect samples. The average accuracy was 90.12%, 96.80% and 89.37% respectively. Different pre-processing techniques were tried to find that first derivative was optimal for methods of libraries and max-min normalization was optimal for that of classifiers. The results obtained from these studies indicated both libraries and classifier methods could detect the expired drugs effectively, and they should be used complementarily in the fast-screening. Copyright © 2014 Elsevier B.V. All rights reserved.
When is a search not a search? A comparison of searching the AMED complementary health database via EBSCOhost, OVID and DIALOG.

Science.gov (United States)

Younger, Paula; Boddy, Kate

2009-06-01

The researchers involved in this study work at Exeter Health library and at the Complementary Medicine Unit, Peninsula School of Medicine and Dentistry (PCMD). Within this collaborative environment it is possible to access the electronic resources of three institutions. This includes access to AMED and other databases using different interfaces. The aim of this study was to investigate whether searching different interfaces to the AMED allied health and complementary medicine database produced the same results when using identical search terms. The following Internet-based AMED interfaces were searched: DIALOG DataStar; EBSCOhost and OVID SP_UI01.00.02. Search results from all three databases were saved in an endnote database to facilitate analysis. A checklist was also compiled comparing interface features. In our initial search, DIALOG returned 29 hits, OVID 14 and Ebsco 8. If we assume that DIALOG returned 100% of potential hits, OVID initially returned only 48% of hits and EBSCOhost only 28%. In our search, a researcher using the Ebsco interface to carry out a simple search on AMED would miss over 70% of possible search hits. Subsequent EBSCOhost searches on different subjects failed to find between 21 and 86% of the hits retrieved using the same keywords via DIALOG DataStar. In two cases, the simple EBSCOhost search failed to find any of the results found via DIALOG DataStar. Depending on the interface, the number of hits retrieved from the same database with the same simple search can vary dramatically. Some simple searches fail to retrieve a substantial percentage of citations. This may result in an uninformed literature review, research funding application or treatment intervention. In addition to ensuring that keywords, spelling and medical subject headings (MeSH) accurately reflect the nature of the search, database users should include wildcards and truncation and adapt their search strategy substantially to retrieve the maximum number of appropriate
BrAD-seq: Breath Adapter Directional sequencing: a streamlined, ultra-simple and fast library preparation protocol for strand specific mRNA library construction.

Directory of Open Access Journals (Sweden)

Brad Thomas Townsley

2015-05-01

Full Text Available Next Generation Sequencing (NGS is driving rapid advancement in biological understanding and RNA-sequencing (RNA-seq has become an indispensable tool for biology and medicine. There is a growing need for access to these technologies although preparation of NGS libraries remains a bottleneck to wider adoption. Here we report a novel method for the production of strand specific RNA-seq libraries utilizing inherent properties of double-stranded cDNA to capture and incorporate a sequencing adapter. Breath Adapter Directional sequencing (BrAD-seq reduces sample handling and requires far fewer enzymatic steps than most available methods to produce high quality strand-specific RNA-seq libraries. The method we present is optimized for 3-prime Digital Gene Expression (DGE libraries and can easily extend to full transcript coverage shotgun (SHO type strand-specific libraries and is modularized to accommodate a diversity of RNA and DNA input materials. BrAD-seq offers a highly streamlined and inexpensive option for RNA-seq libraries.

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