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Sample records for metabolisme du medicament

  1. Sulphite metabolism; Metabolisme du sulfite

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    Fromageot, P; Chapeville, F [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1960-07-01

    Although the formation of sulphite by micro-organisms was observed as early as 1914 by Neuberg, it was only in 1932 that Nightingale showed it to be present inside cells, in the case of tomato leaf stalks, its formation being due to the reaction: SO{sub 3}H{sup -} + (S{sub 2}O{sub 3}){sub 2}{sup --} {yields} S{sub 2}O{sub 3}{sup --} + O{sub 3}S{sub 2}O{sub 3}{sup --}. The presence of the thiosulphate formed was shown by the high refractive index of its barium salt. Today we have a certain amount of data concerning the formation and use of sulphite in the living cell, even through the knowledge is still incomplete. In this article we will describe and discuss the facts which are known, with particular reference to the oxidation of sulphite. (author) [French] Si la formation de sulfite par des micro-organismes a ete observee des 1914 par Neuberg, sa presence a l'interieur des cellules a ete demontree pour la premiere fois par Nightingale en 1932, dans des tiges et des feuilles de tomates, par la reaction: SO{sub 3}H{sup -} + (S{sub 2}O{sub 3}){sub 2}{sup --} {yields} S{sub 2}O{sub 3}{sup --} + O{sub 3}S{sub 2}O{sub 3}{sup --}. Le thiosulfate forme etait mis en evidence par l'indice de refraction eleve de son sel de baryum. Aujourd'hui on possede un certain nombre de donnees, cependant encore tres incompletes, sur la formation du sulfite et son utilisation par la cellule vivante. Dans cet expose nous decrirons et discuterons quelques-unes de ces acquisitions, tout particulierement celles relatives a l'oxydation du sulfite. (auteur)

  2. Some aspects of sulphite metabolism in plants; Quelques aspects du metabolisme du sulfite chez les vegetaux

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    Perez-Milan, Hernan

    1958-05-15

    As sulphite appears to be an intermediate substance in the degradation of sulphur-containing amino acids, and has an important metabolic role, notably for plants, this research thesis aims at comparing transformations which may occur for a same chemical compound (the sulphite) in various organisms belonging to different species or kingdoms. More particularly, the author studied the formation of sulphite in vegetal tissues, and the oxidisation of sulphite into sulfate within these tissues. In vitro experiments have been performed with oat, while in vivo experiments have been performed on tobacco plants [French] Le sulfite apparait comme une substance intermediaire de la degradation des acides amines soufres. Son role dans la biosynthese de certains d'entre eux, problematique chez les mammiferes, est certain chez les oiseaux, qui, a cet egard, se comportent comme des autotrophes partiels, puisqu'ils reduisent le sulfate en sulfite. On s'apercoit ainsi qu'un degre d'evolution moindre confere au sulfite une importance metabolique plus grande. On peut s'attendre a trouver chez les vegetaux un role encore accru pour le sulfite. Le present travail entre dans ce cadre d'etudes comparees des transformations que peut subir un meme type de compose chimique: le sulfite, dans divers organismes appartenant a des especes ou a des regnes differents. Les donnees acquises exposees ici auront trait aux deux points suivants: I - La formation du sulfite dans les tissus vegetaux, II - L'oxydation dans ces tissus, du sulfite en sulfate. L'avoine nous a servi comme materiel de depart pour les experiences faites in vitro. Cette plante presente en effet l'avantage de se bien cultiver en toutes saisons, de se broyer facilement, et d'etre depourvue au maximum de mucilages, de resines, substances genantes pour l'analyse ulterieure. Les essais faits in vivo, ont mis en oeuvre des plants de tabac, qui permettent une nutrition par le petiole ou par la tige particulierement aisee.

  3. Metabolism of cerium 144 in rat. Distribution - elimination - dosimetry; Metabolisme du cerium 144 chez le rat. Distribution - elimination - dosimetrie

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    Remy, Jacques

    1959-07-01

    This academic report concerns a study during which cerium 144 has been intravenously injected to three-month old rats under the form of cerium chloride in aqueous solution with pH of 9,5. Rats have then been sacrificed at different times after the injection, and organ or tissue samplings have been performed to study the isotope distribution in their bodies. This allowed the calculation of internal irradiation doses locally received by the animal, and also to identify critical organs with respect to cerium 144. Thus, until the twentieth day after injection, liver is the critical organ. After, it is the skeleton, for the rest of the animal's life. The bone internal irradiation is the highest danger for an internal cerium 144 contamination, due to threats on body hematopoietic functions [French] Le Cerium 144 est injecte a des rats de trois mois par voie intraveineuse, sous forme de chlorure en solution aqueuse a pH = 9,5. Une telle solution est colloidale. Les rats sont sacrifies par groupe de 5 a des temps differents apres l'injection et des prelevements d'organes ou de tissus sont effectues qui permettent d'etudier la distribution de l'isotope dans l'organisme. Cette etude de la distribution du Cerium 144 dans l'organiqme du rat a permis egalement le calcul des doses d'irradiation interne recues localement par l'animal. Ces donnees permettent de definir les organes critiques de l'organisme pour le Cerium 144: Jusqu'au 20eme jour l'organe critique est le foie. Ce sera ensuite le squelette, et ce, pendant toute la vie de l'animal. L'irradiation interne de l'os constitue, en raison des menaces qu'elle comporte pour les fonctions hematopoietiques de l'organisme, le plus grand danger d'une contamination interne par le Cerium 144.

  4. Metabolism of {sup 137}cesium, {sup 137}barium in the rat. Therapeutics of the contamination; Metabolisme du {sup 137}cesium, {sup 137}baryum chez le rat. Therapeutique de la contamination

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    Remy, J; Philippon, A; Lafuma, J; Walter, C [Commissariat a l' Energie Atomique, 92 - Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires. Departement de la Protection Sanitaire, Laboratoire de Radiopathologie

    1967-07-01

    The authors carry out research into the distribution kinetics, the metabolism and the excretion of {sup 137}Cs - {sup 137}Ba in the rat. They show that these phenomena are independent of the method of applying a single dose. The distribution tends to adopt in all cases a typical shape which remains the same depending on the body burden. Biological analysis of the state of the cesium in the biological media shows that it is transported in the free and ionised form. Considering the problem of the method of penetration of the cesium ion in the intracellular medium, and in particular by the in vivo and in vitro kinetic study of the plasma - red cell system, the authors make the assumption that an active transport of cesium occurs by the cell membrane. They thus arrive at an overall picture of the cesium distribution in the organism which is essentially characterized by a dynamic distribution equilibrium between two compartments: 99 per cent of the cesium accumulates in the intracellular pool, 1 per cent in the extracellular liquids. This latter compartment is open to the emunctories. Because, of the active transport by the cell membranes, the intracellular pool is filled rapidly but discharge is slow. This phenomenon is the limiting factor in the decrease of the body burden. From this representation, the authors deduce the reasons for the relative failure of the various therapeutic methods examined up till now by themselves or by other authors. The stimulation of the natural emunctories in the case of diuretics for example, can only improve the purification of the extracellular compartment. Now this latter contains only 1 per cent of the body burden and recharging is slow. Furthermore the methods designed to counteract or inhibit the active transport of cesium by the cell membrane are still at the present time incompatible with the survival of the cell. (authors) [French] Les auteurs etudient experimentalement la cinetique de distribution, le metabolisme et l

  5. Metabolism of {sup 137}cesium, {sup 137}barium in the rat. Therapeutics of the contamination; Metabolisme du {sup 137}cesium, {sup 137}baryum chez le rat. Therapeutique de la contamination

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    Remy, J.; Philippon, A.; Lafuma, J.; Walter, C. [Commissariat a l' Energie Atomique, 92 - Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires. Departement de la Protection Sanitaire, Laboratoire de Radiopathologie

    1967-07-01

    The authors carry out research into the distribution kinetics, the metabolism and the excretion of {sup 137}Cs - {sup 137}Ba in the rat. They show that these phenomena are independent of the method of applying a single dose. The distribution tends to adopt in all cases a typical shape which remains the same depending on the body burden. Biological analysis of the state of the cesium in the biological media shows that it is transported in the free and ionised form. Considering the problem of the method of penetration of the cesium ion in the intracellular medium, and in particular by the in vivo and in vitro kinetic study of the plasma - red cell system, the authors make the assumption that an active transport of cesium occurs by the cell membrane. They thus arrive at an overall picture of the cesium distribution in the organism which is essentially characterized by a dynamic distribution equilibrium between two compartments: 99 per cent of the cesium accumulates in the intracellular pool, 1 per cent in the extracellular liquids. This latter compartment is open to the emunctories. Because, of the active transport by the cell membranes, the intracellular pool is filled rapidly but discharge is slow. This phenomenon is the limiting factor in the decrease of the body burden. From this representation, the authors deduce the reasons for the relative failure of the various therapeutic methods examined up till now by themselves or by other authors. The stimulation of the natural emunctories in the case of diuretics for example, can only improve the purification of the extracellular compartment. Now this latter contains only 1 per cent of the body burden and recharging is slow. Furthermore the methods designed to counteract or inhibit the active transport of cesium by the cell membrane are still at the present time incompatible with the survival of the cell. (authors) [French] Les auteurs etudient experimentalement la cinetique de distribution, le metabolisme et l

  6. Les manifestation oculaires des troubles primitifs du metabolisme des lipides: Étude clinique, génétique et anatomo-pathologique

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    D. Klein

    1955-01-01

    Full Text Available Les lipidoses constituent un groupe d'affections systématisées, caractérisées par une surcharge lipidique des tissus (en premier lieu du système réticulo-endothélial, accessoirement aussi de divers parenchymes. Le processus qui est à la base de ces "thèsaurismoses" consiste en une perturbation primitive du métabolisme des graisses et des substances apparentées, aboutissant à une infiltration lipidique des organes et entraînant des troubles cliniques variés et souvent très graves. La participation prépondérante du système nerveux central et de l'oeil aux désordres cliniques represente un des aspects les plus importants de la pathologie des lipidoses. Toutes ces affections, excepté la maladie de Hand-Schüller-Christian, offrent en outre un intérêt considérable à cause du rôle primordial que joue l'hérédité comme facteur étiologique. On peut distinguer trois principaux types de lipidoses, groupés d'aprés les substances thésaurisées: les lipidoses à phosphatides, qui peuvent être subdivisées en A. les idioties amaurotiques (surcharge en gangliosides et B. la maladie de Niemann-Pick (sphingomyélines; les lipidoses à cérébrosides (cérasine représentées par la maladie de Gaucher; les lipidoses à cholestérol ou xanthomatoses.

  7. Early Post-Irradiation Changes in the Metabolism of Biogenic Amines; Les Changements Precoces du Metabolisme des Amines Biogenes apres Irradiation

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    Deanovic, Z [Institut Rudjer Boskovic, Zagreb, Yugoslavia (Croatia)

    1971-03-15

    There is accumulating evidence for the radiation-induced release of biogenic amines from their body stores. Having in mind the high patho-physiological activity of these ''local'' hormones and ''neuro-hormones'', it is reasonable to assume that they play an important role in the pathogenesis of the acute radiation syndrome. Under these pathological conditions the possible synergic and antagonistic effects of biogenic amines due to their complex interactions must be taken into consideration. The extent and dose-dependence of post-irradiation changes in the metabolism of histamine, serotonin, catecholamines and acetylcholine will be examined regarding particularly the search for biochemical indicators of radiation injury. The determination of bio-amines and their metabolites in urine seems to be a suitable method for following up those metabolic changes which could be of a biodosimetrical and/or prognostical value. Data published on this subject, obtained in experimental animals as well as in man, have been reviewed and the applicability of these tests is discussed. (author) [French] Des preuves se sont accumulees, qui demontrent que les amines biogenes sont liberees de leurs depots sous l'effet des rayonnements ionisants. Etant donne la grande activite pathophysiologique de ces hormones 'locales' et 'neurohormones', il est raisonnable de considerer que ces substances biogenes jouent un role important dans la pathogenese du syndrome aigu d'irradiation. Dans ces conditions pathologiques il faut tenir compte des effets synergiques et antagonistes des bio-amines, lies a des interactions compliquees. Les changements metaboliques en fonction de la dose recue font l'objet d'un examen qui englobe les alterations quantitatives de .'histamine, de la serotonine, des catecholamines et de l'acetylcholine et dont l'objectif est la recherche sur des indicateurs biochimiques de la lesion provoquee par l'irradiation. L'analyse des bio-amines et de leurs metabolites dans les urines

  8. Synthesis of phenobarbital {sup 14}C - 5 (1964); Synthese du phenobarbital {sup 14}C - 5 (1964)

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    Benakis, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    Phenobarbital (Luminal), well known as a hypnotic agent, plays also an important role in the medical treatment of epilepsy. With the object of studying the metabolism of this medicament in the living system, the synthesis of phenobarbital marked in position 2 of the pyrimidinic ring has been effected. It has been necessary, in order to carry out to research into the metabolism of this product, to have a phenobarbital marked in position 5 of the pyrimidinic ring. This synthesis, making it possible to introduce C-14 into position 5 of the pyrimidinic ring, consists of seven stages starting from C-14 carboxyl benzoic acid having a specific activity of 25 mc/mM. The melting point of the final product is 172 - 173 deg. C and its specific activity is 11.15 mc/mM. The overall radioactive yield of the pure product, with respect to the original benzoic acid (10 mM) is of the order of 3 per cent. The purity of the product has been controlled by paper chromatography; it is of the order of 99 per cent. (author) [French] Le phenobarbital (Luminal) bien connu comme agent hypnotique, joue egalement un role important dans la medication anti-epileptique. Pour l'etude du metabolisme de ce medicament dans l'organisme vivant, nous avons synthetise le phenobarbital marque en position 2 du cycle pyrimidinique. Afin de poursuivre la recherche du metabolisme de ce produit, il a ete necessaire de disposer du phenobarbital marque en position 5 du cycle. pyrimidinique. Cette synthese, permettant l'introduction du {sup 14}C en position 5 du cycle pyrimidinique, comporte sept etapes, au depart de l'acide benzoique carboxyle {sup 14}C, d'une activite specifique de 25 mc/mM. Point de fusion du produit final: 172 - 173 deg. C Activite specifique: 11,15 mC/mM. Rendement total radioactif du produit pur, par rapport a l'acide benzoique de depart sur 10 mM, de l'ordre de 3 pour cent. La purete du produit a ete controlee par chromatographie sur papier; elle est de l'ordre de 99 pour cent. (auteur)

  9. Use of tritiated water as indicator of the water metabolism on normal and operate patients; Emploi de l'eau tritiee comme indicateur du metabolisme de l'eau chez les sujets normaux et operes

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    Fallot, P; Aeberhardt, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1955-07-01

    Water disruptions are very frequent during the medical and surgical affections. In order to study the kinetics of the water exchanges as well as the determination of the total water of the body, we have chosen tritiated water as indicator. This work presents a rapid process, faithful and sensitive of dosage of the Tritium in the biologic liquids. This method has been applied to the survey of the intestinal absorption of water among normal subjects and during some medical and surgical affections. The exam of the experimental curves permitted to get information concerning the kinetics of water ingested as well as of data on the volume of total water of the human body and on the biologic period of the Tritium in the organism. (M.B.) [French] Les perturbations hydriques sont tres frequentes au cours des affections medicales et chirurgicales. Afin d'etudier la cinetique des echanges hydriques ainsi que la determination de l'eau totale du corps, nous avons choisit l'eau tritiee comme indicateur. Ce travail presente une methode rapide, fidele et sensible de dosage du Tritium dans les liquides biologiques. Cette methode a ete appliquee a l'etude de l'absorption intestinale de l'eau chez des sujets normaux et au cours de certaines affections medicales et chirurgicales. L'examen des courbes experimentales ont permis d'obtenir des renseignements concernant la cinetique de l'eau ingeree ainsi que des donnees sur le volume d'eau totale du corps humain et sur la periode biologique du Tritium dans l'organisme. (M.B.)

  10. A new method for studying iodine metabolism; the isotopic equilibrium method - kinetic and quantitative aspects of measurements made on rats; Une nouvelle methode d'etude du metabolisme de l'iode: la methode d'equilibre isotopique - aspects cinetiques et quantitatifs obtenus chez le rat

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    Simon, C. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-05-15

    The isotopic equilibrium method which has been developed in the case of the rat has made it possible to measure the absolute values of the principal parameters of iodine metabolism in this animal. The quantities and concentrations of iodine have been measured in the thyroid gland and in the plasma with a sensitivity of 0.001 {mu}g of {sup 127}I. This sensitivity has made it possible to measure pools as small as the iodide and the free iodotyrosines of the thyroid and to demonstrate the absence of free iodotyrosines in the plasma of the normal rat. In vivo, the isotopic equilibrium method has made it possible to measure the iodine content of the thyroid gland and to calculate the intensity of this gland's secretion without removing it. By double labelling with {sup 125}I and {sup 131}I the isotopic equilibrium method has made it possible to measure the flux, intensity of the intrathyroidal recycling as well as the turnover rates of all the iodine containing compounds of the thyroid gland. For this gland no precursor-product relationship has been found between The iodotyrosines (MIT and DIT) and the iodothyronines (T{sub 4} and T{sub 3}). The absence of this relationship is due to the heterogeneity of the thyroglobulin turnover. It has been shown furthermore that there exists in the plasma an organic fraction of the iodine which is different to thyroglobulin and which is renewed more rapidly than the circulating hormones T{sub 3} and T{sub 4}. The isotopic equilibrium method is very useful for series measurements of iodine. It makes it possible furthermore to improve the biochemical fractionations by adding carriers without affecting the subsequent {sup 127}I measurements. (author) [French] La methode d'equilibre isotopique, mise au point chez le rat, a permis de mesurer en valeur absolue les principaux parametres du metabolisme de l'iode chez cet animal. Les quantites ou les concentrations d'iode ont ete mesurees pour la thyroide et pour le

  11. A new method for studying iodine metabolism; the isotopic equilibrium method - kinetic and quantitative aspects of measurements made on rats; Une nouvelle methode d'etude du metabolisme de l'iode: la methode d'equilibre isotopique - aspects cinetiques et quantitatifs obtenus chez le rat

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    Simon, C [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-05-15

    The isotopic equilibrium method which has been developed in the case of the rat has made it possible to measure the absolute values of the principal parameters of iodine metabolism in this animal. The quantities and concentrations of iodine have been measured in the thyroid gland and in the plasma with a sensitivity of 0.001 {mu}g of {sup 127}I. This sensitivity has made it possible to measure pools as small as the iodide and the free iodotyrosines of the thyroid and to demonstrate the absence of free iodotyrosines in the plasma of the normal rat. In vivo, the isotopic equilibrium method has made it possible to measure the iodine content of the thyroid gland and to calculate the intensity of this gland's secretion without removing it. By double labelling with {sup 125}I and {sup 131}I the isotopic equilibrium method has made it possible to measure the flux, intensity of the intrathyroidal recycling as well as the turnover rates of all the iodine containing compounds of the thyroid gland. For this gland no precursor-product relationship has been found between The iodotyrosines (MIT and DIT) and the iodothyronines (T{sub 4} and T{sub 3}). The absence of this relationship is due to the heterogeneity of the thyroglobulin turnover. It has been shown furthermore that there exists in the plasma an organic fraction of the iodine which is different to thyroglobulin and which is renewed more rapidly than the circulating hormones T{sub 3} and T{sub 4}. The isotopic equilibrium method is very useful for series measurements of iodine. It makes it possible furthermore to improve the biochemical fractionations by adding carriers without affecting the subsequent {sup 127}I measurements. (author) [French] La methode d'equilibre isotopique, mise au point chez le rat, a permis de mesurer en valeur absolue les principaux parametres du metabolisme de l'iode chez cet animal. Les quantites ou les concentrations d'iode ont ete mesurees pour la thyroide et pour le plasma avec une

  12. Metabolism and toxicology of plutonium-239 - evaluation of the internal contamination of persons professionally exposed (1963); Metabolisme et toxicologie du plutonium 239 - evaluation de la contamination interne des personnes professionnellement exposees (1963)

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    Henry, Ph [Commissariat a l' Energie Atomique, Centre de Production de Plutonium, Marcoule (France). Centre d' Etudes Nucleaires

    1963-07-01

    After reviewing the main metabolic and toxicological properties of plutonium 239 as well as the professional norms now in force, the report considers the difficult problem of the evaluation of the internal contamination of persons professionally exposed. This evaluation is dependent on the practical organisation of the supervision involved: - systematic supervision by periodic analysis of urinary Pu and special supervision in the case of incidents by an examination adapted to each case. A simple interpretation of the systematic analyses, as well as the evaluation methods used in the main cases of occidental contamination are outlined. (author) [French] Apres avoir passe en revue les principales proprietes metaboliques et toxicologiques du plutonium 239, ainsi que les normes professionnelles actuellement en vigueur, le rapport aborde le probleme difficile de l'evaluation de la contamination interne des personnes professionnellement exposees. Cette evaluation est fonction de l'organisation pratique de la surveillance: - surveillance systematique par des analyses periodiques de Pu urinaire et surveillance speciale en cas d'incidents par des examens appropries a chaque cas. Une interpretation simple des analyses systematiques, ainsi que des methodes d'evaluation utilisables dans les principaux cas de contamination accidentelle sont exposees. (auteur)

  13. Automatic Sample and Data Processing in Studies of Calcium Metabolism in Rats; Traitement Automatique des Echantillons et des Donnees dans l'Etude du Metabolisme Calcique chez le Rat; Avtomaticheskaya obrabotka obraztsov i dannykh pri izuchenii obmena kal'tsiya u krysy; Tratamiento Automatico de las Muestras y de los Datos en el Estudio del Metabousmo del Calcio en la Rata

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    Onkelinx, C.; Richelle, L. J.; Debras, J. [Universite de Liege (Belgium)

    1965-10-15

    the standard deviation shown by the measurements for each sample; (2) analysing the specific activity curve of the plasma and expressing it in mathematical terms; comparing the theoretical curve with the experimental measurements; (3) evolving the complete model by calculating the various parameters. The results are printed out in full and also punched onto cards by the computer for further processing later. The advantages of digital over analogue computers for this work are discussed. (author) [French] L'etude du metabolisme calcique du rat en fonction de l'age ou de divers traitements exige une experimentation portant sur de grandes series d'animaux. Ces explorations requierent, d'une part, l'etude de l'evolution avec le temps de la concentration serique d'une dose traceuse de {sup 45}Ca injectees par voie intraveineuse et, d'autre part, la mesure d'un bilan chimique et radiochimique. La combinaison de ces deux types d'informations et leur traitement mathematique conduit a la resolution d'un modele general du metabolisme calcique qui permet de connaitre la taille des compartiments echangeables et la grandeur de differents vecteurs tels que l'absorption intestinale, l'excretion renale et intestinale, le depot et la sortie de calcium de l'os. Les travaux ont ete facilites par le developpement de methodes automatiques de mesure des echantillons et de traitement des donnees, qui font l'objet du memoire. Traitement des echantillons: les mesures de radioactivite sont effectuees sur des echantillons plasmatiques de faible volume (20 a 40 {lambda}) preleves de maniere repetee et sur des collections fecales et urinaires faites entre deux limites de temps. La chaine de mesure utilisee comporte un detecteur a anti-coiencidence de faible bruit de fond, un passeur d'echantillons et un ensemble electronique dont les mesures sont enregistrees par une machine imprimante. Les methodes originales de preparation des echantillons et les performances de la chatoie de mesure sont

  14. Nucleic Acids and Protein Metabolism of Bone Marrow Cells Studied by Means of Tritiumlabelled Precursors; Etude du Metabolisme des Acides Nucleiques et des Proteines dans les Cellules de la Moelle Osseuse, a l'Aide de Precurseurs Trities; 0418 0437 0443 0414 ; Estudio con Ayuda de Precursores Tritiados del Metabolismo de los acidos Nucleicos y de las Proteinas en las Celulas de la Medula Osea;

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    Gavosto, F. [Istituto di Clinica Medica Generale e Centro di Studi Fisico-Biologici, Universita de Turin, Turin (Italy)

    1962-02-15

    avantages que presente l'emploi de composes trities pour l'autoradiographie. En effet les electrons du tritium ont une energie maximum de 0,018 MeV, correspondant a un parcours d'environ 1 micron dans une emulsion photographique, ce qui permet d'obtenir le plus fort degre de resolution possible aux niveaux cellulaire et infracellulaire. Ce phenomene est particulierement utile pour l'etude du metabolisme de tissus comme la moelle osseuse, qui sont composes de differents types de cellules a divers stades de differenciation. Cette technique a ete utilisee pour l'etude du metabolisme des acides nucleiques et des proteines des cellules normales et leucemiques de la moelle osseuse. L'auteur a etudie le metabolisme de l'ADN a l'aide d'un precurseur specifique, la thymidine tritiee. Il a decele certaines differences importantes dans les pourcentages de cellules marquees, en comparant les elements normaux et leucemiques au meme stade de maturation. Il a constate, en particulier, que dans les cellules d'un sujet atteint de leucemie aiguee, le taux d'incorporation de la thymidine etait beaucoup plus faible, ce qui prouve une diminution de la capacite de proliferation de ces cellules par rapport aux myeloblastes normaux. L'auteur a utilise la meme technique pour etudier le metabolisme de l'ARN et des proteines, a l'aide des precurseurs suivants: uridine, leucine et phenylalanine tritiees. Il est maintenant admis en biologie cellulaire qu'il existe un rapport etroit entre le metabolisme de l'ARN et celui des proteines; l'auteur a demontre qu'il existait egalement un rapport constant entre l'incorporation de l'uridine et des acides amines, dans les cellules normales de la moelle osseuse. Dans les cellules de sujets atteints de leucemie aiguee, l'incorporation de l'ARN et des precurseurs protidiques, bien qu'elle differe dans chaque cas, est toujours nettement plus faible. De plus, le rapport entre l'incorporation de l'uridine et celle des amino-acides varie constamment dans ces cellules

  15. Simultaneous Study of Thyroxine and Triiodothyronine ({sup 125}I-T{sub 4} and {sup 131}I T{sub 3}) Metabolism: Diagnostic Value in Thyroid and Metabolic Diseases; Etude Simultanee du Metabolisme de la Thyroxine et de la Triiodothyronine ({sup 125}I-T{sub 4} - {sup 131}I T{sub 3}) - Interet Diagnostique dans les Maladies Thyroiediennes et Metaboliques

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    Jaffiol, C.; Pastorello, R.; Baldet, L.; Robin, M.; Mirouze, J. [Clinique des Maladies Metaboliques et Endocriniennes, Montpellier (France)

    1971-02-15

    anomalies of the thyroid function in various metabolic diseases. (author) [French] Les parametres caracteristiques du metabolisme des deux hormones thyroiediennes (periode biologique, vitesse de renouvellement, espace de dilution, pool, quantite quotidiennement consommee d'hormones), sont etudies apres injection intraveineuse simultanee de 200 {mu}Ci de {sup 125}I T{sub 4} et de {sup 131}I T3. Les echantillons de plasma sont soumis a une chromatographie prealable pour separer la fraction hormonale des iodures. Sont ainsi etudies 10 sujets temoins, 3 hyperthyroidiens, 6 hypothroidiens, 41 diabetiques, 2 syndromes nephrotiques, 5 insuffisants renaux. Dans les maladies thyroiediennes, l'analyse des resultats confirme une difference significative entre les sujets temoins, les hypo et les hyperthyroidiens chez lesquels la consommation quotidienne d'hormones est tres abaissee ou au contraire augmentee. L'etude parallele de la capacite de transport de la thyroxine par la TBG et la TBPA autorise l'interpretation de ces variations qui semblent inversement proportionnelles a la quantite de thyroxine liee aux proteines vectrices du plasma. L'interet pratique de ce test doit etre souligne chez les sujets soumis as une surcharge par produit de contraste organo-iode et dans les formes atypiques de la maladie ou les investigations biologiques classiques sont d'interpretation difficile. Dans le diabete sucre, l'insulinotherapie augmente la quantite quotidiennement consommee de T{sub 4} et surtout de T{sub 3} tandis que les sulfamides hypoglycemiants ne paraissent avoir aucune incidence. Dans les syndromes nephrotiques, la vitesse de renouvellement de la T{sub 4} est accrue tandis que la clearance renale de cette hormone est tres elevee, a l'inverse de celle de la T{sub 3} moins liee aux proteines. Au cours de l'insuffisance renale, la vitesse de renouvellement de la T{sub 4} est tres abaissee tandis que son espace de dilution et son pool sont accrus. Ces resultats confirment l'interet de

  16. In vivo effects of a chronic contamination by uranium or cesium 137 on the pharmaceutical metabolism, of the vitamin D and cholesterol; Effets in vivo d'une contamination chronique par l'uranium ou le cesium 137 sur le metabolisme du medicament, de la vitamine D et du cholesterol

    Energy Technology Data Exchange (ETDEWEB)

    Souidi, M

    2006-11-15

    In conclusion, an animal model, miming the chronic contamination of the populations exposed to the uranium, was used for the first time to show that the chronic ingestion of a weak dose of depleted uranium can affect the level of active vitamin D without modifying the mineral homeostasis. This study shows that this radionuclide can lead molecular modifications of the CYPs and the nuclear receivers involved in the metabolism of the vitamin D not only at the level of the liver and kidney but also at the level of the independent metabolism in the brain. The deficiency in vitamin D can provoke osseous diseases such as the rickets at the child and the osteomalacia at the adult. The three categories of population the most exposed to this deficiency are the infants, the pregnant women and the old persons. Strong prevalence of the vitamin D deficiency associated with a chronic exposure to uranium could lead to osseous disorders. To verify this hypothesis, it will be necessary secondly to realize this study on individuals animal models predisposed to the rickets or to the osteomalacia. (N.C.)

  17. Contribution to research on the metabolism of fission product. Studies on the physico-chemical state and the metabolic fate of radio-cerium solution; Contribution a l'etude du metabolisme des produits de fission. Recherches sur l'etat physico-chimique et le devenir metabolique des solutions de radiocerium

    Energy Technology Data Exchange (ETDEWEB)

    Aeberhardt, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1961-07-01

    This paper describes a study of the physico-chemical state of radio-cerium in dilute solutions on the tracer scale, as a function of the pH of the solution. The way in which this radioelement is transported in the blood is studied in vitro and in vivo, with reference to the ionic or colloidal state of the radio-cerium used. The distribution of cerium amongst the various components of the blood is studied by a new method of blood fractionation and by paper electrophoresis. Evidence of a cerium globulin connection is shown in the case of ionic cerium. A study of the initial distribution of radio-cerium in rats, after intravenous administration of ionic or colloidal solutions, shows considerable differences according to the physico-chemical state of the cerium injected. (author) [French] Ce travail presente une etude de l'etat physico-chimique du radiocerium en solutions diluees a l'echelle des indicateurs, en fonction du pH de la solution. En fonction de l'etat ionique ou colloidal du radiocerium utilise, le mode de transport de ce radioelement dans le sang est etudie in vitro et in vivo. La distribution du cerium entre les differents constituants du sang est etudiee par une methode nouvelle de fractionnement du sang et par electrophorese sur papier. L'existence d'une liaison cerium-globuline est mise en evidence dans le cas du cerium ionique. L'etude de la distribution initiale du radiocerium, chez le rat apres administration par voie veineuse de solutions ionique ou colloidale, montre des differences importantes en fonction de l'etat physico-chimique du cerium injecte. (auteur)

  18. Transcriptomic effects of depleted uranium on acetylcholine and cholesterol metabolisms in Alzheimer's disease model; Effets transcriptomiques de l'uranium appauvri sur les metabolismes de l'acetylcholine et du cholesterol chez un modele de maladie d'Alzheimer

    Energy Technology Data Exchange (ETDEWEB)

    Lestaevel, Ph.; Bensoussan, H.; Racine, R.; Airault, F.; Gourmelon, P.; Souidi, M. [Direction de la radioprotection de l' Homme, service de radiobiologie et d' epidemiologie, laboratoire de radiotoxicologie experimentale, institut de radioprotection et de surete nucleaire, BP no 17, 92262 Fontenay-aux-Roses cedex (France)

    2011-02-15

    Some heavy metals, or aluminium, could participate in the development of Alzheimer disease (AD). Depleted uranium (DU), another heavy metal, modulates the cholinergic system and the cholesterol metabolism in the brain of rats, but without neurological disorders. The aim of this study was to determine what happens in organisms exposed to DU that will/are developing the AD. This study was thus performed on a transgenic mouse model for human amyloid precursor protein (APP), the Tg2576 strain. The possible effects of DU through drinking water (20 mg/L) over an 8-month period were analyzed on acetylcholine and cholesterol metabolisms at gene level in the cerebral cortex. The mRNA levels of choline acetyl transferase (ChAT) vesicular acetylcholine transporter (VAChT) and ATP-binding cassette transporter A1 (ABC A1) decreased in control Tg2576 mice in comparison with wild-type mice (respectively -89%, -86% and -44%, p < 0.05). Chronic exposure of Tg2576 mice to DU increased mRNA levels of ChAT (+189%, p < 0.05), VAChT (+120%, p < 0.05) and ABC A1 (+52%, p < 0.05) compared to control Tg2576 mice. Overall, these modifications of acetylcholine and cholesterol metabolisms did not lead to increased disturbances that are specific of AD, suggesting that chronic DU exposure did not worsen the pathology in this experimental model. (authors)

  19. A concise classification of bencao (materia medica).

    Science.gov (United States)

    Zhao, Zhongzhen; Guo, Ping; Brand, Eric

    2018-01-01

    Books that record the sources and applications of medicinal materials are commonly known as bencao ( materia medica ) in China. Bencao ( materia medica ) literature review is the very first step in the standard authentication procedure of Chinese medicinals. As an important part of China's cultural heritage, these various bencao ( materia medica ) texts represent centuries of accumulated wisdom in combating disease and preserving health. In this short review, bencao ( materia medica ) classics of China are broadly divided into three major categories in our routine practice: mainstream bencao ( materia medica ), thematic bencao ( materia medica ) and regional bencao ( materia medica ). The overall significance and current situation of exploration of bencao ( materia medica ) literature are summarized as well.

  20. Application of Tritiated Compounds to the Midge Chironomus and some Aspects of the Metabolism of Salivary Gland Chromosomes; Emploi de Composes Trities pour l'Etude du Chironome et de Certains Aspects du Metabolisme des Chromosomes des Glandes Salivaires; 041f 0440 0438 043c 0414 ; Aplicacion de Compuestos Tritiados a la Mosca Cbironomus y Algunos Aspectos del Metabolismo en los Cromosomas de las Glandulas Salivares

    Energy Technology Data Exchange (ETDEWEB)

    Pelling, C. [Max-Planck-Institut fuer Biologie, Tuebingen, Federal Republic of Germany (Germany)

    1962-02-15

    The investigations were carried out on the salivary gland chromosomes of Chironomus tentons. Tritiated compounds (H{sup 3}-thymidine, H{sup 3}-uridine, H{sup 3}-amino-acids), injected into the haemolymph of the larvae should indicate the place of incorporation within the giant chromosomes. After fixation of the salivary glands autoradiographs of the squash-preparations were made. The autoradiographs show that giant chromosomes are most suitable to localize the activity at chromosomal structures with high resolution. DNA-synthesis (thymidine), RNA-synthesis (uridine) and protein-synthesis within the cell could be followed by determining the time and approximatively the quantity of incorporation: Contrary to the protein-synthesis, the DNA-synthesis and the RNA-synthesis are restricted to the chromosomes. The essential physiological activity of the chromosomes seems to be represented by RNA synthesis which takes place at certain distinct loci (nuceolar organizers, ''Balbiani-rings'', puffs, and other chromosomal bands). The report discusses some features of RNA synthesis. (author) [French] Les recherches ont porte sur les chromosomes des glandes salivaires du chironomus tentans. On a injecte les composes trities (thymidine, uridine, acides amines) dans l'hemolymphe de la larve en vue de determiner le lieu d'incorporation dans les chromosomes geants. Apres fixation par les glandes salivaires, on a procede a des autoradiographies de preparations broyees. Ces autoradiographies montrent que ce sont les chromosomes geants qui permettent le mieux de localiser,- avec une forte resolution, l'activite au niveau chromosomique. L'auteur a pu suivre la synthese de l'ADN (thymidine), la synthese de l'ARN (uridine) et la synthese des proteines a l'interieur de la cellule en determinant le temps et le taux approximatif d'incorporation. A l'inverse de la synthese des proteines, la synthese de l'ADN et celle de l'ARN sont limitees aux chromosomes. L'activite physiologique essentielle

  1. Experimental results concerning the metabolism of ingested iodine-131 in adult sheep under lactation; Resultats experimentaux relatifs au metabolisme de l'iode 131 ingere chez la brebis adulte en lactation

    Energy Technology Data Exchange (ETDEWEB)

    Daburon, F.; Capelle, A.; Tricaud, Y.; Nizza, P. [Commissariat a l' Energie Atomique, 92 - Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires. Departement de la Protection Sanitaire, Laboratoire-etable de Radiobiologie Appliquee

    1967-07-01

    The authors give the results of a series of experiments on metabolism of ingested iodine-131 in adult sheep under lactation; the measurement were carried out over a number of years from 1961 to 1966. The work was concerned initially with the fixation of iodine 131 in the thyroid gland, with the calculation of radiation doses absorbed and with ways of showing up any possible radiation damage in the gland. The modes of absorption of iodine 131 and its elimination through milk, urine and the faeces were then considered. Finally, a last chapter is devoted to changes in the radioactivity of the blood and of the milk, to variations of the PBI level of the blood serum as to different methods for measuring this level. (authors) [French] Les auteurs rapportent les resultats d'une serie d'experimentations relatives au metabolisme de l'iode 131 ingere chez la brebis adulte en lactation, et qui se sont etalees sur plusieurs annees, de 1961 a 1966. Les etudes ont porte d'abord sur les aspects de la fixation de l'iode 131 dans la thyroide, avec le calcul des doses de rayonnements absorbees et les moyens de mettre en evidence les radiolesions eventuelles de la glande. Ensuite ont ete traitees les modalites de l'absorption de l'iode 131 et de son elimination par le lait, les urines et les feces. Enfin un dernier chapitre a ete consacre a l'evolution de la radioactivite du sang et du lait, aux variations ainsi qu'aux divers moyens d'evaluation du taux de PBI du serum sanguin. (auteurs)

  2. Experimental results concerning the metabolism of ingested iodine-131 in adult sheep under lactation; Resultats experimentaux relatifs au metabolisme de l'iode 131 ingere chez la brebis adulte en lactation

    Energy Technology Data Exchange (ETDEWEB)

    Daburon, F; Capelle, A; Tricaud, Y; Nizza, P [Commissariat a l' Energie Atomique, 92 - Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires. Departement de la Protection Sanitaire, Laboratoire-etable de Radiobiologie Appliquee

    1967-07-01

    The authors give the results of a series of experiments on metabolism of ingested iodine-131 in adult sheep under lactation; the measurement were carried out over a number of years from 1961 to 1966. The work was concerned initially with the fixation of iodine 131 in the thyroid gland, with the calculation of radiation doses absorbed and with ways of showing up any possible radiation damage in the gland. The modes of absorption of iodine 131 and its elimination through milk, urine and the faeces were then considered. Finally, a last chapter is devoted to changes in the radioactivity of the blood and of the milk, to variations of the PBI level of the blood serum as to different methods for measuring this level. (authors) [French] Les auteurs rapportent les resultats d'une serie d'experimentations relatives au metabolisme de l'iode 131 ingere chez la brebis adulte en lactation, et qui se sont etalees sur plusieurs annees, de 1961 a 1966. Les etudes ont porte d'abord sur les aspects de la fixation de l'iode 131 dans la thyroide, avec le calcul des doses de rayonnements absorbees et les moyens de mettre en evidence les radiolesions eventuelles de la glande. Ensuite ont ete traitees les modalites de l'absorption de l'iode 131 et de son elimination par le lait, les urines et les feces. Enfin un dernier chapitre a ete consacre a l'evolution de la radioactivite du sang et du lait, aux variations ainsi qu'aux divers moyens d'evaluation du taux de PBI du serum sanguin. (auteurs)

  3. [Irrigants and intracanal medicaments in endodontics].

    Science.gov (United States)

    Zehnder, Matthias; Lehnert, Birgit; Schönenberger, Kathrin; Waltimo, Tuomas

    2003-01-01

    Modern, biologic root canal therapy should be performed with suitable irrigating solutions and intracanal medicaments. The goal of endodontic treatment is to free the treated tooth from infection and prevent reinfection as thoroughly as possible by means which do not put the organism at risk. In this review of the literature, an evidence-based concept for irrigation and medication of root canal systems is presented. Irrigants and medicaments are discussed with respect to their antimicrobial, tissue-dissolving and endotoxin-decontaminating capacity in relation to their systemic toxicity. Recent findings pertaining to interactions of root canal medicaments and irrigating solutions and their impact on a sound irrigating and medicating concept are discussed.

  4. [A accurate identification method for Chinese materia medica--systematic identification of Chinese materia medica].

    Science.gov (United States)

    Wang, Xue-Yong; Liao, Cai-Li; Liu, Si-Qi; Liu, Chun-Sheng; Shao, Ai-Juan; Huang, Lu-Qi

    2013-05-01

    This paper put forward a more accurate identification method for identification of Chinese materia medica (CMM), the systematic identification of Chinese materia medica (SICMM) , which might solve difficulties in CMM identification used the ordinary traditional ways. Concepts, mechanisms and methods of SICMM were systematically introduced and possibility was proved by experiments. The establishment of SICMM will solve problems in identification of Chinese materia medica not only in phenotypic characters like the mnorphous, microstructure, chemical constituents, but also further discovery evolution and classification of species, subspecies and population in medical plants. The establishment of SICMM will improve the development of identification of CMM and create a more extensive study space.

  5. Tritiated Thymidine as Tracer in DNA Metabolism and Cell Dynamics of Experimental Myeloid Leukaemia; Emploi de la Thymidine Tritiee comme Indicateur pour l'Etude du Metabolisme de l'ADN et de la Dynamique des Cellules dans la Leucemie Myeloide Experimentale; 0422 0440 0438 0442 0414 ; Empleo de la Timidina Tritiada como Indicador para Estudiar el Metabolismo del Acido Desoxirribonucleico y la Dinamica Celular en la Leucemia Mieloide Experimental

    Energy Technology Data Exchange (ETDEWEB)

    Zajicek, G.; Rosin, A.; Gross, J. [Department of Experimental Medicine and Cancer Research, Hebrew University, Hadassah Medical School, Jerusalem (Israel)

    1962-02-15

    rapidite avec laquelle ces myelocites disparaissaient du sang. Ils ont cherche a determiner la presence de cellules marquees dans differents organes et constate que, peu de temps apres l'injection, ces cellules sont surtout capturees par les poumons, puis par la rate et, dans une moindre mesure, par le foie. Apres 24 heures, il n'etait plus possible de deceler de cellules marquees dans aucun des organes. On a ainsi obtenu des indications sur le sort de myelocites leucemiques dans differents organes, chez l'animal normal et chez l'animal leucemique. Au cours d'experiences in vitro, les auteurs ont ajoute a une 'suspension cellulaire' de la thymidine tritiee d'une concentration de 1 {mu}c/cm{sup 3}. Ils ont observe qu'au cours du marquage in vitro le nombre de cellules marquees etait 40 fois superieur a celui des mitoses. (La meme observation a ete faite apres adminisration de thymidine tritiee in vivo.) Les auteurs ont determine le taux d'incorporation de la thymidine tritiee. Us ont fait des essais pour des concentrations comprises entre 0,0036 {mu} mole x 10{sup -3} et 1,8 {mu}mole x 10{sup -3} et ont constate que le pourcentage des cellules qui fixent l'indicateur est constant quelle que soit la concentration. Le nombre de grains par noyau augmentait en meme temps que la concentration de la thymidine administree. Apres une periode d'incubation de 120 minutes, on n'a plus constate de mitose de cellulose marquees. De plus, le processus d'incorporation a ete le meme, que l'indicateur ait ete ajoute au debut de la periode d'incubation ou apres 160 minutes. L'addition, a differents intervalles de temps, n'a pas modifie le pourcentage des cellules marquees, mais le nombre de grains par noyau a augmente apres chaque administration de thymidine tritiee. Les cellules en suspension n'ont pas toutes fixe la meme quantite de thymidine tritiee. Les auteurs ont procede a des mesures quantitatives, notamment a des comptages de grains, et ont constate que les cellules leucemiques ne

  6. Evaluation of brain metabolism and hemodynamics in neonates; Exploration du metabolisme et de l`hemodynamique du cerveau du nouveau-ne

    Energy Technology Data Exchange (ETDEWEB)

    Messer, J. [Centre Hospitalier Universitaire, 67 - Strasbourg (France); Haddad, J.

    1996-09-01

    Evaluation of brain metabolism and hemodynamics has become a necessity in the neonatal period. Cerebral perfusion, oxygen consumption, and/or metabolism can be studied. Doppler, near-infrared tissual spectroscopy, and magnetic resonance spectroscopy are noninvasive techniques that can be used at the bedside. Available techniques for investigating the central nervous system are reviewed, with emphasis on their usefulness for establishing a diagnosis and a prognosis and for making therapeutic decisions. In perinatal asphyxia, these techniques are often useful for guiding therapeutic decisions. It may be appropriate to discuss discontinuation of therapy in patients with cerebral hyperemia, loss of vaso-reactivity to CO{sub 2}, and failure of oxidative phosphorylations responsible for a decrease in the PCr/Pi ratio, an increase in lactate levels, and a decrease in ATP levels. In other situations, these investigations can shed light on pathophysiologic mechanisms in preterm infants. Use of these techniques varies across neonatal units. Each unit should select the techniques that provide the best yields under the conditions prevailing in that unit. (authors). 31 refs., 2 tabs.

  7. Kaempferol, a flavonoid compound from Gynura medica induced ...

    African Journals Online (AJOL)

    Background: Kaempferol, a natural flavonoid, has been shown to induce cancer cell apoptosis and cell growth inhibition in several tumors. Previously we have conducted a full investigation on the chemical constituents of Gynura medica, kaempferol and its glycosides are the major constituents of G. medica. Here we ...

  8. [Management of Chinese materia medica market based on information asymmetry].

    Science.gov (United States)

    Yang, Guang; Wang, Nuo; Guo, Lan-Ping; Wang, Yong-Yan; Huang, Lu-Qi; Liu, Jin-Xin

    2013-12-01

    Pharmaceutical market is a typical market with information asymmetry, and which can lead to "lemons" problem. In all developed countries, firms must receive regulatory approval to market a pharmaceutical product. Such administrative department including SFDA, EMA, FDA and so on. Chinese materia medica is a special part of pharmaceutical market in China. The management of Chinese materia medica is a special challenge in China.

  9. [Substance basis research on Chinese materia medica is one of key scientific problems of inheriting, development and innovation of Chinese materia medica].

    Science.gov (United States)

    Yang, Xiu-wei

    2015-09-01

    The compound Chinese materia medica is the medication pattern of the traditional Chinese medicine for the disease prevention and treatment. The single Chinese materia medica (mostly in decoction pieces) is the prescription composition of the compound Chinese materia medica. The study of the effective substance basis of Chinese materia medica should be based on the chemical compositions of the compound Chinese materia medica as an entry point considering the different status of "Monarch, Minister, Assistant, and Guide" for a certain single Chinese materia medica in the different compound Chinese materia medica while substance basis research of a certain single Chinese materia medica should be a full component analysis as well as both stable and controllable quality. Substance basis research on Chinese materia medica is one of key scientific problems of inheriting, development and innovation of Chinese materia medica.

  10. [Influence of compendium of Materia Medica on the materia medica in the late period of the Chosun Dynasty].

    Science.gov (United States)

    Oh, Chae-Kun

    2012-08-31

    In this paper, I investigated the influence of Compendium of Materia Medica (CM) on Records for Rural Life of Chosun Gentlemen (RRC), and refuted Miki Sakae's opinion, CM did not have much impact on the Materia Medica in the late period of the Chosun Dynasty. When Li Shizhen published CM, it resulted in a shift of mainstream of Materia Medica in Eastern Asia from Classified Emergency Materia Medica to CM and a new categorizing system of Materia Medica by CM led to the division of Materia Medica into medicine and natural history. It is obvious that doctors of the Chosun Dynasty also adopted the latest achievements of Materia Medica by CM, but so far there have been few studies to clarify this. Seo yugu was a scholar of the Realist School of Confucianism during the late period of the Chosun Dynasty, and RRC is his representative work. RRC is a massive encyclopedia of natural history that covers vast areas of science from agriculture, floriculture, writing and drawing, architecture, diet, and medicine, among others which absorbed the achievements of CM, the best Materia Medica book at that time. Miki Sakae also highly regarded the encyclopedic knowledge of RRC, but devalued the results of Materia Medica. He only described a part of RRC's Materia Medica, nurturing volume, on the view of life nurturing and mentioned that it had been strongly influenced by China. According to this study, a large portion of RRC, especially regarding Materia Medica, depends on CM. Seo yugu had accepted the categorizing system and new medicinal information of CM, at the same time he modified the categorizing system of CM practically by the subject of each volume of RRC. We can find many quotations of CM except the nurturing volume, but other books, Treasured Mirror of Eastern Medicine, Materia Medica for Relief of Famines are also quoted. Furthermore, Seo yugu emphasized the differences of natural environments between Chosun and China, and specified the editing criteria, "to be useful in

  11. Liver and water metabolism; Foie et metabolisme de l'eau

    Energy Technology Data Exchange (ETDEWEB)

    Fallot, P. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires; Faculte des Sciences de Grenoble, 38 (France)

    1959-07-01

    The causes for the disturbance of hydro-electrolytic equilibrium observed in cirrhosis patients are far from clear. Studies on the static distribution of liquid in the organism and also on anomalies in the distribution of deuterium oxide and tritiated water provide no direct explanation of the nature of the water retaining mechanism. At the period when the illness is established, endocrine factors and electrolytic perturbations contribute to maintaining or increasing oliguresis, but they cannot be held solely responsible in the initial stages of evolution. An explanation of the ascites should therefore be looked for in a non-functioning of the polygonal or Kupffer cells. The hypothesis of an insufficient rejection of water outside the lymph spaces of the liver during cirrhosis is put forward, but the experimental demonstration of such a phenomenon proves very difficult. (author) [French] Les causes du desequilibre hydroelectrolytique observe chez les malades cirrhotiques sont loin d'etre elucidees. Les etudes de la repartition du liquide de l'organisme ainsi que celles des anomalies de la distribution de l'oxyde de deuterium et de l'eau tritiee n'apportent aucune explication directe sur la nature du mecanisme de la retention de l'eau. A la periode d'etat de la maladie, les facteurs endocriniens et les perturbations electrolytiques contribuent a entretenir ou a accroitre l'oligurie mais ils ne peuvent etre seuls invoques lors des stades initiaux de l'evolution. Il faudrait donc rechercher dans un dysfonctionnement des cellules polygonales ou kupfferiennes l'explication de l'ascite. L'hypothese d'une insuffisance du rejet de l'eau hors des espaces lymphatiques du foie au cours de la cirrhose est evoquee mais la demonstration d'un tel phenomene s'avere tres difficile sur le plan experimental. (auteur)

  12. Liver and water metabolism; Foie et metabolisme de l'eau

    Energy Technology Data Exchange (ETDEWEB)

    Fallot, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires; Faculte des Sciences de Grenoble, 38 (France)

    1959-07-01

    The causes for the disturbance of hydro-electrolytic equilibrium observed in cirrhosis patients are far from clear. Studies on the static distribution of liquid in the organism and also on anomalies in the distribution of deuterium oxide and tritiated water provide no direct explanation of the nature of the water retaining mechanism. At the period when the illness is established, endocrine factors and electrolytic perturbations contribute to maintaining or increasing oliguresis, but they cannot be held solely responsible in the initial stages of evolution. An explanation of the ascites should therefore be looked for in a non-functioning of the polygonal or Kupffer cells. The hypothesis of an insufficient rejection of water outside the lymph spaces of the liver during cirrhosis is put forward, but the experimental demonstration of such a phenomenon proves very difficult. (author) [French] Les causes du desequilibre hydroelectrolytique observe chez les malades cirrhotiques sont loin d'etre elucidees. Les etudes de la repartition du liquide de l'organisme ainsi que celles des anomalies de la distribution de l'oxyde de deuterium et de l'eau tritiee n'apportent aucune explication directe sur la nature du mecanisme de la retention de l'eau. A la periode d'etat de la maladie, les facteurs endocriniens et les perturbations electrolytiques contribuent a entretenir ou a accroitre l'oligurie mais ils ne peuvent etre seuls invoques lors des stades initiaux de l'evolution. Il faudrait donc rechercher dans un dysfonctionnement des cellules polygonales ou kupfferiennes l'explication de l'ascite. L'hypothese d'une insuffisance du rejet de l'eau hors des espaces lymphatiques du foie au cours de la cirrhose est evoquee mais la demonstration d'un tel phenomene s'avere tres difficile sur le plan experimental. (auteur)

  13. [Probe into monitoring mechanism of Chinese materia medica resources].

    Science.gov (United States)

    Zhang, Xiao-Bo; Li, Da-Ning; Guo, Lan-Ping; Lu, Jian-Wei; Sun, Li-Ying; Huang, Lu-Qi

    2013-10-01

    Focusing on the problems of Chinese materia medica resources,and combining with the national Chinese materia medica resources survey, the paper probes into monitoring mechanism of Chinese materia medica resources. The establishment of the monitoring mechanism needs one organization and management agencies to supervise and guide monitoring work, one network system to gather data information, a group of people to perform monitoring work, a system of technical methods to assure monitoring work scientific and practical, a series of achievements and products to figure out the methods for solving problems, a group of monitoring index system to accumulate basic data, and a plenty of funds to keep normal operation of monitoring work.

  14. The antiepileptic Materia Medica of Pediacus Dioscorides.

    Science.gov (United States)

    Eadie, M J

    2004-09-01

    Since it was written about the middle of the 1st Century AD, and up to comparatively recent times, the great Herbal, or Materia Medica, of Dioscorides provided medicine with its chief source of information about what were then considered therapeutic substances. The work contained data on various materials of botanical, biological and mineral origin which were claimed to provide benefit to sufferers from epilepsy, though often with no clear underlying rationale for their use. Some of these materials continued to be used as antiepileptic remedies over many centuries till they were finally recognised to be without useful effect in the disorder. The longest survivor amongst the Dioscoridean antiepileptic remedies was a rather esoteric one, viz. two stones taken from the belly of a young swallow during the rising phase of the moon and also whilst the swallow's parent birds were absent from the nest. The stones, or one of them, were worn against the skin of the seizure sufferer. The use of the swallow stones for epilepsy was recommended as late as in the writings of Thomas Willis (1675).

  15. The Metabolism of Tritium-Labelled Epinephrine in Man; Metabolisme de l'Adrenaline Tritiee dans l'Organisme Humain; 041c 0435 0414 ; Metabolismo de la Adrenalina Marcada con Tritio en el Hombre

    Energy Technology Data Exchange (ETDEWEB)

    Labrosse, E. H.; Axelrod, J.; Kopin, I. J.; Kety, S. S. [National Institute of Health, Bethesda, MD (United States)

    1962-02-15

    It was of interest to us to study the metabolism of epinephrine in normal human subjects. Studies of epinephrine metabolism in animals have indicated the possible routes of its metabolism, but the doses, both of radioactivity and of the catechol amine, have been greater than the levels which are safe to use in humans. Also earlier studies of the metabolism of this hormone in humans have been limited by the relatively low specific activity of the labelled epinephrine. The use of tritium-labelled epinephrine (7-H{sup 3}-dl-epinephrine- d-bitartrate) has made possible more complete recovery of the administered radioactivity, and the higher specific activity (greater than 300 {mu}c/mg) has allowed isolation and quantification of new metabolites. In twelve normal human males 92.6 {+-} 7.7% of the tritium in the infused H{sup 3}-epinephrine was excreted into the urine within 54 h following the infusion of the tritium-labelled epinephrine. The tritium-labelled urinary constituents were as follows: unchanged epinephrine 6.8 {+-} 1.5%, free metanephrine 5.2 {+-} 1.1%, metanephrine glucuronide 6.0 {+-} 1.5%, metanephrine sulphate 29.5 {+-} 9.0%, 3-methoxy-4-hydroxyphenylglycol 7.1 {+-} 1.4%, free and conjugated 3,4-dihydroxymandelic acid 1.6 {+-} 0-6% and 3-methoxy-4-hydroxymandelic acid 41.2 {+-} 8.4%. As demonstrated by this and related experiments, the biological application of tritium-labelled epinephrine has made possible a much more complete understanding of the metabolism of this important hormone in humans. (author) [French] L'etude du metabolisme de l'adrenaline dans l'organisme de l'homme normal a presente un reel interet. Des etudes faites sur les animaux avaient montre quelles etaient les voies possibles de ce metabolisme, mais les doses de radioactivite et de catecholamine employees etaient superieures a celles qui peuvent etre administrees a l'homme sans presenter de danger. Les etudes anterieures sur le metabolisme de cette hormone chez l'homme avaient ete

  16. LES MEDICAMENTS FALSIFIES, CRIME SANS CHATIMENT

    Directory of Open Access Journals (Sweden)

    Marc GENTILINI

    2017-05-01

    Full Text Available Le trafic de faux médicaments n’est pas un phénomène récent, mais un fléau qui s’aggrave. Plus mortel que le Paludisme et plus rentable que le trafic des drogues, il menace tant la santé des populations que le développement économique des pays les plus pauvres. Des anticancéreux aux traitements des dysfonctionnements érectiles, princeps ou génériques, tous les types de médicaments font l’objet de falsification. Profitant de la mondialisation des échanges et de l’essor d’Internet, ce trafic mortifère s’est développé et s’étend désormais sur les 5 continents. Considéré comme « le plus gros marché noir du monde », il reste pourtant sous-estimé, voire méconnu, du grand public, des professionnels de santé et des dirigeants politiques. La prise de conscience à tous les niveaux des risques engendrés par les médicaments falsifiés est une urgence vitale.

  17. [The introduction of compendium of materia medica and praxis in the late Joseon dynasty].

    Science.gov (United States)

    Oh, Chaekun; Kim, Yongjin

    2011-06-30

    Sakae Miki said Classified Emergency Materia Medica had been the dominant standard of herbology throughout Joseon Dynasty, and that Compendium of Materia Medica had only been accepted so lately that a few books used herbological result of it in the late Joseon Dynasty. But according to Visiting Old Beijing Diary written by Munjoong Seo in 1690, Compendium of Materia Medica was in fact introduced before the year 1712, the year Miki Sakae argued to be the year Compendium of Materia Medica was accepted to Joseon officially. Now, we can assume that the introducing year of Compendium of Materia Medica was faster than Miki Sakae's opinion by the following reasons; the effort of Joseon government and intellectuals to buy new books of Ming & Ching; the publishing year of the book for living in countryside regarded as the first citing literature of Compendium of Materia Medica. And the True Records of the Joseon Dynasty and many collections written by intellectuals in the 18th century show that the herbological knowledge from Compendium of Materia Medica had already spread to the corners of Joseon Dynasty. Thus we can make the following assumption: Classified Emergency Materia Medica and Compendium of Materia Medica had coexisted in the late Joseon Dynasty. Sakae Miki suggested 6 examples which used Compendium of Materia Medica in the late Joseon Dynasty. I reviewed two of them in this paper, Essentials of Materia Medica & Handbook of Prescriptions from Materia Medica. Essentials of Materia Medica quoted Compendium of Materia Medica briefly focusing clinical use, and Handbook of Prescriptions from Materia Medica also re-compiled Compendium of Materia Medica to practical use according to the form of Treasured Mirror of Eastern Medicine. It means that the results of Compendium of Materia Medica have been used positively, based on the herbology of materia medica from countryside. From this point of view, the hyphothesis there weren't any herbological progress after accepting

  18. Filiation et consommation de medicaments psychotropes

    Directory of Open Access Journals (Sweden)

    Alain Ducousso-Lacaze

    Full Text Available A partir de deux entretiens semi-directifs l’auteur présente certains aspects des résultats d’une recherche clinique réalisée avec des patients de l’hôpital général consommant des médicaments psychotropes. Il s’agit de mette en évidence comment, pour certains patients, la consommation et la prescription prennent un sens par rapport aux enjeux de la filiation narcissique. Les analyses cliniques portent essentiellement sur la fonction de support imaginaire de la transmission que peuvent revêtir les médicaments ainsi que leur rôle dans les conflits entre appartenance et différenciation à l’égard du groupe familial.

  19. Chinese materia medica used in medicinal diets.

    Science.gov (United States)

    Tan, Fang; Chen, Yalin; Tan, Xiaolei; Ma, Yunyun; Peng, Yong

    2017-07-12

    Medicinal diets have a history of more than 2000 years. Locally referred to as yaoshan (Chinese: ), a medicinal diet is understood in China as a dietary product that combines herbs and food with the purpose of preventing and treating diseases or improving health under the guidance of traditional Chinese medicine theory. Medicinal diets are used in Chinese people's daily life and in specialized restaurants. Hundreds of Chinese materia medica (CMM) are used in medicinal diets; however, a comprehensive evaluation of medicinal diets is lacking. This is an exploratory study that aims to identify the CMM that are most frequently used in medicinal diets and to provide an updated view of the current situation of medicinal diets in China. A field study of 1221 people in 32 Chinese provinces was conducted over a period of approximately 6 months and included various types of interviews as well as a written questionnaire. Two approaches were used to analyse the data collected in the survey: (1) estimating the frequency of CMM consumed in daily diets; and (2) collecting CMM used in medicinal diet restaurants. Complementary information on the selected CMM was obtained from relevant databases, including PubMed, Google Scholar, Baidu Scholar, CNKI, and Web of Science. Ten CMM were reported as commonly used by more than 50% of the participants. Among these 10 species, most medicinally used parts were seeds and fruits. Pharmacological data from the literature revealed that these species are associated with a wide spectrum of biological properties, including antitumour (80%), antioxidant (50%), anti-diabetic (40%), antilipemic (40%), anti-aging (40%), antimicrobial (40%) and cardioprotective (40%) activities. Our survey shows that most medicinal diet restaurants are located in the eastern part of China, with the greatest numbers being found in Beijing and Guangzhou. Only Dioscoreae Rhizoma, Lycii Fructus, Chrysanthemi Flos and Longan Arillus were frequently consumed both in daily

  20. [Construction of biopharmaceutics classification system of Chinese materia medica].

    Science.gov (United States)

    Liu, Yang; Wei, Li; Dong, Ling; Zhu, Mei-Ling; Tang, Ming-Min; Zhang, Lei

    2014-12-01

    Based on the characteristics of multicomponent of traditional Chinese medicine and drawing lessons from the concepts, methods and techniques of biopharmaceutics classification system (BCS) in chemical field, this study comes up with the science framework of biopharmaceutics classification system of Chinese materia medica (CMMBCS). Using the different comparison method of multicomponent level and the CMMBCS method of overall traditional Chinese medicine, the study constructs the method process while setting forth academic thoughts and analyzing theory. The basic role of this system is clear to reveal the interaction and the related absorption mechanism of multicomponent in traditional Chinese medicine. It also provides new ideas and methods for improving the quality of Chinese materia medica and the development of new drug research.

  1. Effect of intracanal medicament on bond strength of fibre posts

    Directory of Open Access Journals (Sweden)

    Huda Melike Bayram

    2016-07-01

    Full Text Available The aim of this study was to evaluate the effect of calcium hydroxide (CH, triple antibiotic paste (TAP and double antibiotic paste (DAP on the push-out bond strengths of three different self-adhesive resin cements. Forty-eight single-rooted human maxillary central incisors were selected. The crowns were removed and the root canals were performed. After the irrigation protocols, the post space was prepared. The teeth were then randomly divided into a control group (no intracanal medicament and three medicament groups (n = 12 for each group. After three weeks, the medicaments were removed using 17% ethylenediaminetetraacetic acid, 2.5% sodium hypochlorite and EndoActivator agitation. The teeth were divided into three subgroups according to the fibre-post luting cement: Maxcem Elite, RelyX Unicem and BisCem. The specimens were sectioned and the push-out test was performed. One-way analysis of variance and Tukey's post hoc tests were used for statistical analyses. Regarding the type of cement, BisCem had significantly lower bond strength values than Maxcem and RelyX. There was no significant difference between the bond strength values of Maxcem and RelyX (p > 0.05. The TAP-RelyX group had the highest bond strength value and the DAP-BisCem group had the lowest bond strength value. RelyX and Maxcem had higher bond strength to root canal dentin than BisCem. The bond strength of BisCem, RelyX and Maxcem was not negatively affected by the use of DAP, CH and TAP as intracanal medicaments.

  2. Bread as Food and Medicament in Oribasius’ Writings

    OpenAIRE

    Kokoszko, Maciej; Jagusiak, Krzysztof; Dybała, Jolanta

    2016-01-01

    Treatises left by Oribasius (first and foremost his Collectiones medicae and Eclogae medicamentorum) preserve a vast body of information on the varieties of bread eaten in late antiquity, characterise them from the point of view of dietetics, list medical conditions in which a given variety is especially beneficial, and name medical preparations which include the product. The present study elaborates on Oribasius’ dietetic knowledge and his input into the development of dietetic discourse (na...

  3. Salving Distribution Information System on PT. Anugerah Argon Medica

    OpenAIRE

    Yunus, Halimah

    2015-01-01

    Medica's Argon godsend constitute moving firm at salving sell area filing system and its reporting is still utilize archives and ledger before utilizes.Data collecting on observational it utilizes to methodic observation, interview and `studi` is library.Meanwhile software development methods that is utilized is model Waterfall. Implementation of model Waterfall this was worded utilize `document`'s flowing charts, diagram context, `flow`'s data diagramdesignoutput` is input design databasedat...

  4. LE MEDICAMENT DU MOIS. Vedolizumab (Entyvio(R)), nouveau traitement des maladies inflammatoires intestinales.

    OpenAIRE

    Van Kemseke, Catherine; Louis, Edouard; Reenaers, Catherine

    2015-01-01

    Anti-TNF agents are highly effective in treating inflammatory bowel diseases, but loss of response and side-effects leading to drug interruption are often reported. New molecules are needed to treat these patients. Vedolizumab is a fully humanized anti-body inhibiting the migration of circulating lymphocytes to the gut by binding the integrin alpha4beta7. In ulcerative colitis, clinical response, remission and mucosal healing were observed at 6 weeks in 47%, 17% and 40% of the patients, respe...

  5. [Ecological agriculture: future of Good Agriculture Practice of Chinese materia medica].

    Science.gov (United States)

    Guo, Lan-ping; Zhou, Liang-yun; Mo, Ge; Wang, Sheng; Huang, Lu-qi

    2015-09-01

    Based on the ecological and economic problems in Good Agriculture Practice (GAP) of Chinese material medica, we introduced the origin, concept, features and operative technology of eco-agriculture worldwide, emphasizing its modes on different biological levels of landscape, ecosystem, community, population, individual and gene in China. And on this basis, we analyzed the background and current situation of eco-agriculture of Chinese materia medica, and proposed its development ideas and key tasks, including: (1) Analysis and planning of the production pattern of Chinese material medica national wide. (2) Typical features extraction of regional agriculture of Chinese materia medica. (3) Investigation of the interaction and its mechanism between typical Chinese materia medica in each region and the micro-ecology of rhizosphere soil. (4) Study on technology of eco-agriculture of Chinese materia medica. (5) Extraction and solidification of eco-agriculture modes of Chinese materia medica. (6) Study on the theory of eco-agriculture of Chinese materia medica. Also we pointed out that GAP and eco-agriculture of Chinese material medica are both different and relative, but they are not contradictory with their own features. It is an irresistible trend to promote eco-agriculture in the GAP of Chinese material medica and coordinate ecological and economic development.

  6. Cerebral blood flow and metabolism analysis in parkinsonian disorders; Pathologie extrapyramidale. Apport de l'imagerie de perfusion et du metabolisme (TEP, TEM)

    Energy Technology Data Exchange (ETDEWEB)

    Defebvre, L. [Hopital Roger Salengro, Service de Neurologie, 59 - Lille (France)

    1999-12-01

    Main metabolic and hemodynamic abnormalities detected by single photon emission computerized tomography and positron emission tomography in extra-pyramidal disorders are reported. In the first stage of Parkinson's disease, cortical metabolism and perfusion can be in normal range or moderately and uniformly reduced. A significant decrease may appear with the disease evolution. Marked abnormalities are observed in parkinsonian patients with dementia (subcortical dementia), involving especially the frontal cortex. A marked diffuse cortical hypo-metabolism (temporal, parietal, occipital and frontal cortex) may suggest the diagnosis of dementia with Lewy bodies, especially in case of fluctuating cognitive decline with recurrent visual hallucinations. In progressive supra-nuclear palsy, a frontal cortex hypo-metabolism is reported precociously, preceding sometimes the cognitive impairment. Metabolic pattern find in multiple system atrophy reflects dysfunction of both nigrostriatal pathways and striatum, with a decrease glucose uptake in putamen and caudate nucleus which also involves cerebellum for the patients with cerebellar syndrome. In cortico-basal degeneration, asymmetric fronto-parietal and striatal hypo-metabolism observed in the controlateral hemisphere to the clinically most affected side, constitute the main characteristic well correlated with apraxia. (author)

  7. [Status and suggestions for adjuvant standard for Chinese materia medica processing in China].

    Science.gov (United States)

    Yang, Chun-Yu; Cao, Hui; Wang, Xiao-Tao; Tu, Jia-Sheng; Qian, Zhong-Zhi; Yu, Zhi-Ling; Shang, Yue; Zhang, Bao-Xian

    2017-04-01

    In this paper, the status of adjuvant standard for Chinese materia medica processing in the Chinese Pharmacopoeia 2015 edition, the National Specification of Chinese Materia Medica Processing, and the 29 provincial specification of Chinese materia medica was summarized, and the the status including general requirements, specific requirements, and quality standard in the three grade official specifications was collected and analyzed according to the "medicine-adjuvant homology" and "food-adjuvant homology" features of adjuvants. This paper also introduced the research situation of adjuvant standard for Chinese materia medica processing in China; In addition, analyzed and discussed the problems existing in the standard system of adjuvant for Chinese materia medica processing, such as lack of general requirements, low level of standard, inconsistent standard references, and lack of research on the standard, and provided suggestions for the further establishment of the national standards system of adjuvant for Chinese materia medica processing. Copyright© by the Chinese Pharmaceutical Association.

  8. Extraction, Modelling and Purification of Flavonoids from Citrus Medica Peel

    OpenAIRE

    M. Parvathi Nandan; Vangalapati Meena

    2015-01-01

    Soxhlet extraction technique is widely employed for the extraction and separation of chemical constituents in the medicinal plants. Citrus medica L commonly called as Citron belongs to family Rutaceae, is a slow-growing shrub. It is mainly cultivated for the production of edible fruits which are sour in taste like lime and lemon and the main content of a citron fruit is the thick rind, which is very adherent to the segments. From the phytochemical analysis the peel extract is rich source of p...

  9. [Elementary exploration of the origin and development of marine Chinese materia medica].

    Science.gov (United States)

    Guan, Hua-Shi; Fu, Xian-Jun; Wu, Qiang-Ming; Wang, Chang-Yun; Wang, Yu; Jiang, Deng-Zhao

    2009-05-01

    According to archaeological discoveries, humans began to make use of marine natural resources early in the Palaeolithic era. In the Spring and Autumn period and Warring States period, they began to use marine life as medicines and also had simple cognitions on their efficacy and processing. In the Qin and Han dynasties, people further deepened the understanding of the marine Chinese materia medica and created prescriptions making use of marine drugs. In the Tang and Song period, the number of marine Chinese materia medica species and corresponding prescriptions apparently increased. The cognitions of the property, flavor, efficacy as well as the compatible principle of marine Chinese materia medica was further deepened and the scope of their treatment also significantly expanded. In the Ming and Qing dynasties, the cognition of the marine Chinese materia medica was mainly the conclusions of the previous experience. After the founding of the People's Republic of China (PRC), with the development of science and technologies, the ability of exploiting and utilizing the marine Chinese materia medica by people dramatically increased, and the species of marine Chinese materia medica reached more than one thousand. However, the development of marine Chinese materia medica is confronted with new problems; although the number of species of marine Chinese materia medica increased, the understanding of their property and flavor is obviously lagging behind, which seriously affects the clinical application of marine Chinese materia medica.

  10. Relationship of intracanal medicaments to endodontic flare-ups.

    Science.gov (United States)

    Trope, M

    1990-10-01

    The purpose of the study was to compare the effect of three intracanal medicaments on the incidence of post-instrumentation flare-ups. All teeth were instrumented to a predetermined minimum size using a 0.5% solution of sodium hypochlorite as the irrigant. Formocresol, Ledermix, and calcium hydroxide were placed in strict sequence irrespective of the presence or absence of symptoms or radiographic signs of apical periodontitis. The patients were given written post-operative instructions and a prescription for 600 mg ibuprofen to be taken if mild to moderate pain developed. If severe pain and/or swelling developed the patient was instructed to call the office immediately and was considered to have had a flare-up. Twelve flare-ups occurred in teeth with radiographic signs of apical periodontitis; none in teeth without periapical radiolucencies. Six of the twelve flare-ups occurred in retreatment cases and the other six occurred in teeth without previous endodontic treatment. No significant difference was found in the flare-up rate among the three intracanal medicaments.

  11. Review of adverse reactions to injections of Chinese materia medica.

    Science.gov (United States)

    Bian, Zhaoxiang; Shang, Hongcai; Cheng, Chungwah; Wu, Taixiang; Li, Youping; Zhang, Boli

    2010-05-01

    Using Chinese Materia Medica (CM) as injections is an innovation that is proving effective in extensive clinical use in Mainland China. However, recent reports have focused on adverse reactions, ignoring the considerable successes of these preparations. In order to achieve balance in the media and in the minds of the public, we suggest the first step is to clarify the concepts of and differences between adverse drug reactions (ADR) and adverse events (AE) for all concerned-the public, medical practitioners, government officials, and lawmakers. Second, the State Food and Drug Administration should raise the requirements for Chinese Materia Medica Injection (CMI) registration and license approval and emphasize the importance of evidence-based CMI development and evidence-based CMI license approval. Thirdly, drug companies and institutions should reinforce basic research about the quality control of herbs and CMI-drug interactions. Fourth, the Government should clarify the legal responsibilities for CMI approval agencies, CMI developers, medical doctors, and patients. Fifth, the medical association and Government should enhance training for health care professionals concerning the usage of CMIs. And finally sixth, State Food and Drug Administration should monitor the content and quality of the directions for use of CMI. © 2010 Blackwell Publishing Asia Pty Ltd and Chinese Cochrane Center, West China Hospital of Sichuan University.

  12. In Vitro Metabolism of H{sup 3} Thymidine; Metabolisme In Vitro de la Thymidine Tritiee; 041c 0435 0414 ''In Vitro''; Metabolismo In Vitro de la Timidina Tritiada

    Energy Technology Data Exchange (ETDEWEB)

    Rubini, J. R.; Keller, S.; Eisentraut, A. [Veterans Administration Hospital and Southwestern Medical School, Dallas, TX (United States); Cronkite, E. P. [Brookhaven National Laboratory, Upton, Long Island, NY (United States)

    1962-02-15

    The in vitro metabolism and fate of the DNA precursor H{sup 3} thymidine, H{sup 3}TDR, (1.9 c/mMole) was studied in human leukaemic blood and normal dog marrow. New DNA synthesis was estimated by determining the labelling indices and grain counts of cell autoradiograms made from the mixtures at 1 h. Cell labelling could readily be depressed by adding minute amounts of unlabelled TDR to H{sup 3}TDR initially, demonstrating the smallness of the TDR pool. When TDR was added after 20 min to the incubation mixture, no depression of labelling occurred.. This 20 min period defines the H{sup 3}TDR incorporation period. Supernatants at 1 h still contained considerable H{sup 3} activity yet failed to label fresh added cells. These ''used'' supernatants contained H{sup 3}TDR as the major H{sup 3} compound, and only small amounts of H{sup 3} thymine; H{sup 3} water was not formed. Speculations on the mechanisms involved are presented. (author) [French] Le metabolisme et le sort de la thymidine tritiee (1,9 curie/millimole), precurseur de l'ADN, ont ete etudies in vitro dans le sang leucemique humain et la moelle normale du chien. On a evalue la nouvelle synthese de l'ADN en determinant les indices de marquage et en comptant les grains d'autoradiogrammes de cellules effectues a partir de melanges au bout d'une heure. On a pu facilement reduire le marquage des cellules en ajoutant initialement a la thymidine tritiee d'infimes quantites de thymidine non marquee, ce qui met en evidence le faible volume du 'pool' de thymidine. Lorsque la thymidine est ajoutee au melange d'incubation apres 20 minutes, il n'y a pas de diminution du marquage. Cette periode de 20 minutes correspond au delai d'incorporation de la thymidine tritiee. Apres une heure, on constate que les surnageants contiennent encore du tritium tres actif, mais qui ne permet pas de marquer des cellules nouvelles. Les principal composant tritie de ces surnageants 'uses' est la thymidine tritiee; on n'y trouve que de

  13. [Application of zebrafish model organism in the research of Chinese materia medica].

    Science.gov (United States)

    Chen, Lei; Liu, Yi; Liang, Sheng-Wang

    2012-04-01

    Zebrafish has become an important model organism in many fields of biomedical studies and been increasingly used in Chinese materia medica studies in recent years. This article summarized the achievements and prospect for zebrafish as a pharmacological and toxicological tool in the study and development of Chinese materia medica.

  14. [Design and implementation of information management system for Chinese materia medica resources survey].

    Science.gov (United States)

    Wang, Hui; Zhang, Xiao-Bo; Ge, Xiao-Guang; Jin, Yan; Jing, Zhi-Xian; Wang, Ling; Zhao, Yu-Ping; Guo, Lan-Ping; Huang, Lu-Qi

    2017-11-01

    By means of the established Information Management System for Chinese materia medica resources survey, the national, provincial and county level organization, personnel and the implementation of the program of Chinese materia medica resources survey, and the survey team of medicinal plant investigation, photos, Chinese herbal medicine market survey, the traditional Chinese materia medica resources knowledge survey, germplasm resources investigation and the data collation and summary specimen have been realised. Throughout the whole working process of the fourth national Chinese materia medica resources survey, it is ensured that all data were no missing, no repeat, and well stored and managed. The Information Management System can improve the standardization degree of Chinese materia medica resources survey, and maintain the continuity. Copyright© by the Chinese Pharmaceutical Association.

  15. [Application of synthetic biology to sustainable utilization of Chinese materia medica resources].

    Science.gov (United States)

    Huang, Lu-Qi; Gao, Wei; Zhou, Yong-Jin

    2014-01-01

    Bioactive natural products are the material bases of Chinese materia medica resources. With successful applications of synthetic biology strategies to the researches and productions of taxol, artemisinin and tanshinone, etc, the potential ability of synthetic biology in the sustainable utilization of Chinese materia medica resources has been attracted by many researchers. This paper reviews the development of synthetic biology, the opportunities of sustainable utilization of Chinese materia medica resources, and the progress of synthetic biology applied to the researches of bioactive natural products. Furthermore, this paper also analyzes how to apply synthetic biology to sustainable utilization of Chinese materia medica resources and what the crucial factors are. Production of bioactive natural products with synthetic biology strategies will become a significant approach for the sustainable utilization of Chinese materia medica resources.

  16. [Design and implementation of data reporting system for Chinese materia medica resources survey].

    Science.gov (United States)

    Wang, Hui; Zhang, Xiao-Bo; Ge, Xiao-Guang; Jing, Zhi-Xian; Wang, Ling; Zhao, Yu-Ping; Guo, Lan-Ping; Huang, Lu-Qi

    2017-11-01

    The collection, summary and sharing of all kinds of survey data are one of the main tasks and achievements in the national census of Chinese materia medica resources organized and implemented by the State Administration of Traditional Chinese Medicine. It is a key link in the implementation of the national census of Chinese materia medica resources. Based on the client / server architecture, the data reporting system for Chinese materia medica resources survey has been established for reporting system application model of geospatial data service based on Web implementation, through the SOA framework, to achieve the data collection summary of the seven aspects of the local data configuration, data reporting, data verification, data reporting, PDA data import and export, APP data import, track instrument data import. The system services include the general investigation, the focus of investigation, specimen information, herbs sample information, market research, germplasm survey, traditional knowledge survey of these seven aspects of the 312 indicators of the report, serving the Chinese materia medica resource survey of field survey data collection and internal data collation. The system provides the technical support for the national census of Chinese materia medica resources, improves the efficiency of the census of Chinese materia medica resources, and is conducive to the long-term preservation of the data of Chinese materia medica resources census, the transformation and sharing of the results. Copyright© by the Chinese Pharmaceutical Association.

  17. The control of the radioactive pollution of milk (1962); Comment concevoir une surveillance des pollutions radioactives du lait (1962)

    Energy Technology Data Exchange (ETDEWEB)

    Michon, G [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1962-07-01

    Milk, an essential foodstuff, is the object of a supervision and vigilant controls governed by numerous laws which protect its commercial and sanitary qualities. The development of the use of nuclear energy poses and will pose new problems of hygiene and the milk should benefit from controls concerning its possible contamination. Grass-eating animals are particularly subjected to radioactive contaminations and the milk which they produce does not escape contamination because of of its saline composition and of the particular metabolism of the mammary gland. As a result, milk is a contamination integrator and its analysis makes it possible to detect radioelements which can only be detected with great difficulty in an average size plant sample. (author) [French] Le lait, aliment essentiel, fait l'objet d'une surveillance et de controles vigilants regis par de nombreux textes legislatifs qui protegent ses qualites marchandes et sanitaires. Le developpement de l'utilisation de l'energie nucleaire pose et posera de nouveaux problemes d'hygiene et le lait doit beneficier de controles portant sur sa pollution radioactive eventuelle. Les, animaux herbivores sont particulierement exposes aux contaminations radioactives et les laits qu'ils produisent, du fait de leurs compositions salines et du metabolisme particulier de la glande mammaire, n'echappent point aux pollutions. De ce fait, le lait est un integrateur de contamination et son analyse permet de retrouver des radioelements que l'on ne decele qu'avec beaucoup de difficultes sur un echantillon vegetal de taille moyenne. (auteur)

  18. Study of the kinetics of strontium elimination in the rat; Etude de la cinetique de l'elimination du strontium chez le rat

    Energy Technology Data Exchange (ETDEWEB)

    Guilloux, M J; Michon, G [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    A kinetic study of strontium elimination was made on rats after a single oral administration of 3 to 5 {mu}curies of carrier free Sr{sup 90}. The curve showing the body burden in function of time may be considered as the sum of three exponential terms with half-lives of 14 hours, 72 days, 153 days. The term with a half-live of 153 days represents the metabolism of strontium in the bone; it is predominant since the 17. day and its extrapolation to time zero shows that things seem to proceed as if 18 per cent of the administered amount were deposited in the skeleton. (author) [French] La cinetique de l'elimination du strontium chez le rat a ete etudiee apres une administration orale unique de 3 a 5 {mu}curies de {sup 90}Sr repute sans entraineur. La courbe representant la quantite presente dans l'organisme en fonction du temps peut etre assimilee a la somme de trois termes exponentiels de periode 14 heures, 72 jours, 153 jours. Le terme de periode 153 jours represente le metabolisme osseux du strontium, il est preponderant des le 17. jour et son extrapolation au temps zero nous montre qu'en definitive, tout se passe comme si 18 pour cent de la quantite administree etaient deposes dans le squelette. (auteur)

  19. [Research on Japanese monograph of comprehensive dietetic materia medica, the Pao chu bei yong wo ming ben cao (Japanese Materia Medica Prepared for Kitchen)].

    Science.gov (United States)

    Zhou, M; Ye, J

    2017-11-28

    Japanese physicians of Edo Period (1603-1867) wrote many dietetic books, by combining the knowledge system (content and compiling style) and thoughts of diet therapy from China with local condition in Japan. Among them, the Pao chu bei yong wo ming ben cao ( Japanese Materia Medica Prepared for Kitchen ), written by Mukai Genshou, a physician in the early Edo, is the earliest comprehensive work of dietetic materia medica. In this book, the choice and usage of Japanese dietetic materia medica reveals obvious Japanese local color, including the name, morphology, cultivation, collection, identification, nature and flavor, and indication etc., reflecting the sprouting idea of edible herbal plant at the beginning of Edo period and the characteristic of absorbing Chinese diet thoughts by Japanese physician. This is the important first-hand historical material to understand the development of Japanese dietetic herbalism in early Edo and its dietotherapy culture.

  20. Citrus medica: nutritional, phytochemical composition and health benefits - a review.

    Science.gov (United States)

    Chhikara, Navnidhi; Kour, Ragni; Jaglan, Sundeep; Gupta, Pawan; Gat, Yogesh; Panghal, Anil

    2018-04-25

    Citrus medica (Citron) is an underutilized fruit plant having various bioactive components in all parts of the plant. The major bioactive compounds present are iso-limonene, citral, limonene, phenolics, flavonones, vitamin C, pectin, linalool, decanal, and nonanal, accounting for several health benefits. Pectin and heteropolysachharides also play a major role as dietary fibers. The potential impact of citron and its bioactive components to prevent or reverse destructive deregulated processes responsible for certain diseases has attracted different researchers' attention. The fruit has numerous nutraceutical benefits, proven by pharmacological studies; for example, anti-catarrhal, capillary protector, anti-hypertensive, diuretic, antibacterial, antifungal, anthelmintic, antimicrobial, analgesic, strong antioxidant, anticancerous, antidiabetic, estrogenic, antiulcer, cardioprotective, and antihyperglycemic. The present review explores new insights into the benefits of citron in various body parts. Throughout the world, citron has been used in making carbonated drinks, alcoholic beverages, syrup, candied peels, jams, marmalade, cordials, and many other value added products, which suggests it is an appropriate raw material to develop healthy processed food. In the present review, the fruit taxonomical classification, beneficial phytochemicals, antioxidant activities, and health benefits are discussed.

  1. Chinese Marine Materia Medica Resources: Status and Potential.

    Science.gov (United States)

    Fu, Xiu-Mei; Zhang, Meng-Qi; Shao, Chang-Lun; Li, Guo-Qiang; Bai, Hong; Dai, Gui-Lin; Chen, Qian-Wen; Kong, Wei; Fu, Xian-Jun; Wang, Chang-Yun

    2016-03-03

    Chinese marine materia medica (CMMM) is a vital part of traditional Chinese medicine (TCM). Compared with terrestrial TCM, CMMM, derived from specific marine habitats, possesses peculiar chemical components with unique structures reflecting as potent pharmacological activities, distinct drug properties and functions. Nowadays, CMMM appears to be especially effective in treating such difficult diseases as cancers, diabetes, cardio-cerebrovascular diseases, immunodeficiency diseases and senile dementia, and therefore has become an important medicinal resource for the research and development of new drugs. In recent years, such development has attracted wide attention in the field of medicine. In this study, the CMMM resources in China were systematically investigated and evaluated. It was found that the historic experiences of Chinese people using CMMM have continuously accumulated over a period of more than 3600 years, and that the achievements of the research on modern CMMM are especially outstanding. By June 2015, 725 kinds of CMMMs from Chinese coastal sea areas have been identified and recorded, covering 1552 organisms and minerals. More than 3100 traditional prescriptions containing CMMMs have been imparted and inherited. However, the number of CMMMs is less than the 8188 terrestrial TCMs, from more than 12,100 medicinal terrestrial plants, animals and minerals. In the future, the research and development of CMMM should focus on the channel entries (TCM drug properties), compatibility, effective ingredients, acting mechanisms, drug metabolism and quality standard. This study reveals the high potential of CMMM development.

  2. The classification and application of toxic Chinese materia medica.

    Science.gov (United States)

    Liu, Xinmin; Wang, Qiong; Song, Guangqing; Zhang, Guangping; Ye, Zuguang; Williamson, Elizabeth M

    2014-03-01

    Many important drugs in the Chinese materia medica (CMM) are known to be toxic, and it has long been recognized in classical Chinese medical theory that toxicity can arise directly from the components of a single CMM or may be induced by an interaction between combined CMM. Traditional Chinese Medicine presents a unique set of pharmaceutical theories that include particular methods for processing, combining and decocting, and these techniques contribute to reducing toxicity as well as enhancing efficacy. The current classification of toxic CMM drugs, traditional methods for processing toxic CMM and the prohibited use of certain combinations, is based on traditional experience and ancient texts and monographs, but accumulating evidence increasingly supports their use to eliminate or reduce toxicity. Modern methods are now being used to evaluate the safety of CMM; however, a new system for describing the toxicity of Chinese herbal medicines may need to be established to take into account those herbs whose toxicity is delayed or otherwise hidden, and which have not been incorporated into the traditional classification. This review explains the existing classification and justifies it where appropriate, using experimental results often originally published in Chinese and previously not available outside China. Copyright © 2013 John Wiley & Sons, Ltd.

  3. Effects of dentin on the antimicrobial properties of endodontic medicaments.

    Science.gov (United States)

    Haapasalo, Markus; Qian, Wei; Portenier, Isabelle; Waltimo, Tuomas

    2007-08-01

    Successful treatment of apical periodontitis is dependent on the elimination of the infective microflora from the necrotic root canal system. Antimicrobial irrigating solutions and other locally used disinfecting agents and medicaments have a key role in the eradication of the microbes. While most if not all presently used disinfecting agents rapidly kill even the resistant microbes when tested in vitro in a test tube, the effectiveness of the same agents is clearly weaker in the in vivo conditions. Recent studies have given valuable information about the interaction of endodontic disinfecting agents with dentin and other compounds present in the necrotic root canal. As a result of such interactions the antimicrobial effectiveness of several of our key disinfectants may be weakened, or even eliminated under certain circumstances. Different disinfectants show different sensitivity to the action by the various potential inactivators, such as dentin, serum proteins, hydroxyapatite, collagen derived from different sources, and microbial biomass. This review is a summary of our present knowledge of the mostly negative interactions between endodontic disinfecting agents and the various compounds present in the root canal environment.

  4. [Discuss on effect of physical environmental factors on nature of Chinese materia medica].

    Science.gov (United States)

    Tang, Shihuan; Yang, Hongjun; Huang, Luqi

    2010-01-01

    Nature of Chinese materia medica is the nucleus in the theory of Chinese material medica, according to the recognition of Traditional Chinese Medicine, which is the character of the drug related on curative effect. Nature and efficacy of a drug is through the medical material, then, physical environment, including the temperature, humidity, atmospheric water, wind, topography, soil, micro-organism, and so on, influence the growth and development of the medical meterial. In this paper, we researched the explanation on nature of Chinese materia medica in the medical books of past dynasties, combined with the modem research, analyzed the relationship between generative reception and physical environmental factors, and discussed the effect of physical environmental factors on nature of Chinese materia medica. We indicated that the formation of Chinese materia medical nature is that the drug receptive the change of physical environmental factors, and resulted by the synthetic action of the factors, such as climate, soil, biology, topography, etc.

  5. Acta informatica medica is indexed in pubmed and archived in pubmed central.

    Science.gov (United States)

    Masic, Izet

    2013-03-01

    Acta Informatica Medica journal has been accepted for archiving in PubMed Central from 2011 onward. The journal started in 1993 as the official journal of the Society for Medical Informatics of Bosnia and Herzegovina. During the last 3 years, Acta Informatica Medica has een included in almost all prestigious online databases, including PubMed, Scopus and EMBASE. The 20th volume of the journal is fully international, with papers from 18 countries.

  6. The effect of endodontic regeneration medicaments on mechanical properties of radicular dentin

    Science.gov (United States)

    Yassen, Ghaeth H.

    Endodontic regeneration treatment of necrotic immature teeth has gained popularity in recent years. The approach suggests a biological alternative to induce a continuous root development. In this project, three in vitro experiments were conducted to investigate the effect of three medicaments used in endodontic regeneration on mechanical properties and chemical structure of radicular dentin. In the first experiment, we investigated longitudinally the effect of medicaments on the indentation properties of the root canal surface of immature teeth using a novel BioDent reference point indenter. A significant difference in the majority of indentation parameters between all groups was found after one-week and one-month application of medicaments (p double antibiotic paste (DAP) > control > calcium hydroxide [Ca(OH)2]. The four-week exposure of dentin to TAP and DAP caused 43% and 31% increase in total indentation distance outcome, respectively. In the second experiment, we investigated longitudinally the effect of medicaments on the chemical structure of immature radicular dentin by measuring the phosphate/amide I ratios of dentin using Attenuated Total Reflection Fourier Transform Infrared Spectroscopy. Phosphate/amide I ratios were significantly different between the four groups after one week, two weeks and four week application of medicaments (p untreated dentin > DAP-treated dentin > TAP-treated dentin. In the third experiment, we investigated longitudinally the effect of medicaments on root fracture resistance and microhardness of radicular dentin. For the microhardness, the two-way interaction between group and time was significant (pmedicaments caused significant decrease in fracture resistance ranging between 19%-30% after three month application compared to one week application. The three medicaments used in endodontic regeneration caused significant change in the chemical integrity of the superficial radicular dentin and significantly affected the indentation

  7. Inactivation of local root canal medicaments by dentine: an in vitro study.

    Science.gov (United States)

    Haapasalo, H K; Sirén, E K; Waltimo, T M; Ørstavik, D; Haapasalo, M P

    2000-03-01

    The aim of the study was to investigate the inactivation by dentine of the antibacterial activity of various commonly used local root canal medicaments. The medicaments tested were saturated calcium hydroxide solution, 1% sodium hypochlorite, 0.5% and 0.05% chlorhexidine acetate, and 2/4% and 0.2/0.4% iodine potassium iodide. Dentine was sterilized by autoclaving and crushed into powder with a particle size of 0.2-20 microns. Aliquots of dentine suspension were incubated with the medicaments in sealed test tubes at 37 degrees C for 24 h or 1 h before adding the bacteria. In some experiments bacteria were added simultaneously with dentine powder and the medicament. Enterococcus faecalis A197A was used as a test organism. Samples for bacterial culturing were taken from the suspensions at 5 min, 1 h and 24 h after adding the bacteria. Dentine powder had an inhibitory effect on all medicaments tested. The effect was dependent on the concentration of the medicament as well as on the length of the time the medicament was preincubated with dentine powder before adding the bacteria. The effect of calcium hydroxide on E. faecalis was totally abolished by the presence of dentine powder. Similarly, 0.2/0.4% iodine potassium iodide lost its effect after preincubation for 1 h with dentine before adding the bacteria. The effect of 0.05% chlorhexidine and 1% sodium hypochlorite on E. faecalis was reduced but not totally eliminated by the presence of dentine. No inhibition could be measured when full strength solutions of chlorhexidine and iodine potassium iodide were used in killing E. faecalis. The dentine powder model appears to be an efficient tool for the study of interactions between local endodontic medicaments, dentine, and microbes.

  8. The risk of severe salicylate poisoning following the ingestion of topical medicaments or aspirin.

    OpenAIRE

    Chan, T. Y.

    1996-01-01

    Apart from isolated reports of severe salicylate poisoning after ingesting an unusually large amount of a medicinal oil, there are no published data on the threat arising from attempted suicide with topical medicaments containing methyl salicylate or wintergreen oil compared with aspirin tablets. In this retrospective study, the admission plasma salicylate concentrations and clinical presentations were compared in 80 subjects who had taken aspirin tablets (n = 42) or topical medicaments (n = ...

  9. Genetic cytological and biochemical study of a tomato chlorophyll mutant of the xanthic type, obtained by irradiation of the seeds; Etude genetique, cytologique et biochimique d'un mutant chlorophyllien de tomate du type xantha, obtenu par irradiation de graines

    Energy Technology Data Exchange (ETDEWEB)

    Lefort, M; Duranton, J; Galmiche, J M; Roux, E [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    Irradiation of Lycopersicum aesculantum seeds with increasing doses of X-rays and thermal neutrons leads to the appearance of chlorophyll mutations in the descendants of the irradiated seeds. A genetic study of one of these mutants of the xanthic type showed that it was a recessive mutant with typical mono-genetic separation, while the cytological study demonstrated that the differentiation of the plast stopped at the stage of elementary lamella. Finally it is shown that in the light, the mutation brings about a very large deviation of the carbon metabolism towards the synthesis of amino acids and proteins, at the expense of that of glucosides. (author) [French] L'irradiation de graines de Lycopersicum Aesculantum avec des doses croissantes de rayons X et de neutrons thermiques entraine l'apparition de mutations chlorophylliennes dans la descendance des graines irradiees. L'etude genetique d'un de ces mutants du type xantha a montre qu'il s'agissait d'un mutant recessif a disjonction monogenique typique, tandis que l'etude cytologique a revele que la differentiation du plaste s'arretait au stade de lamelles elementaires. Il est apparu enfin qu'a la lumiere la mutation entrainait une deviation tres importante du metabolisme du carbone vers la synthese des acides amines et des proteines, au detriment de celle des glucides. (auteur)

  10. The study of the distribution of Ca{sup 45} with time in the newborn rat by the autoradiography method at - 195 deg; Etude de la distribution du {sup 45}Ca en fonction du temps chez le rat nouveau-ne par la methode d'autoradiographie a -195 deg

    Energy Technology Data Exchange (ETDEWEB)

    Kellershohn, C; Pellerin, P [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1961-07-01

    Ca{sup 45} metabolism has been studied as a function of time by autoradiography at -195 deg. C in the new-born rat after sub-epidermal dorsal injected of 20 micro-curies per animal. This study confirms: 1) The existence of a rapidly exchangeable calcium bone fraction; 2) A considerable intestinal excretion of radio-calcium, much greater than the urinary elimination; 3) A gradual transfer of the activity for the long bones of the epiphyseal to the diaphyseal regions during growth, together with secondary modifications during ossification. (author) [French] Le metabolisme du {sup 45}Ca est etudie en fonction du temps par autoradiographie a -195 deg. C, chez le rat nouveau-ne apres injection sous-epidermique dorsale de 20 microcuries par animal. Cette etude confirme: 1) l'existence d'une fraction calcique osseuse rapidement echangeable; 2) une excretion intestinale considerable du radiocalcium, tres superieure a l'elimination urinaire; 3) un transfert progressif de l'activite pour les os longs des regions epiphysaires aux regions diaphysaires au cours de la croissance, ainsi que les remaniements secondaires au cours de l'ossification. (auteur)

  11. Authentication of Chinese Materia Medica decoction dregs, part 1: comparison of morphological and microscopic features of four Chinese Materia Medica before and after decoction.

    Science.gov (United States)

    Wong, Lailai; Liang, Zhitao; Chen, Hubiao; Zhao, Zhongzhen

    2011-04-01

    Chinese Materia Medica (CMM) decoction dregs are the residues of medicinal materials after decoction. Accurate identification of CMM in decoction dregs will be helpful for exploring the causes of poisoning or other medical incidents arising after the ingestion of CMM decoctions. To determine how decoction affects the characteristics used to authenticate specific CMM, a systematic study was carried out. In this study, two pairs of Materia Medica that are commonly confused-namely, Baizhu (Atractylodis Macrocephalae Rhizoma) and Cangzhu (Atractylodis Rhizoma), Baishao (Paeoniae Alba Radix) and Chishao (Paeoniae Rubra Radix)-were chosen for investigation. Each pair of Materia Medica has similar morphology in appearance, but they have different functions in Chinese clinic. After decoction, with regard to gross morphological characters, the results showed that bark and wood could be easily distinguished. The striation of vessels and fibers became more prominent because of the contraction of parenchymatous cells, but the lignified cells did not. As for the microscopic characteristics, the cells with thickened walls, such as stone cells and fibers, were basically stable. Most of the parenchymatous cells were broken. Crystals of calcium oxalate showed no changes as they were insoluble in water. Starch granules were gelatinized and aggregated in parenchymatous cells. Inulins were substantially reduced in number as they dissolved in water during decoction. According to these changes in morphological and microscopic characteristics after decoction, the dregs of two pairs of Materia Medica could be distinguished. Copyright © 2010 Wiley-Liss, Inc.

  12. KAEMPFEROL, A FLAVONOID COMPOUND FROM GYNURA MEDICA INDUCED APOPTOSIS AND GROWTH INHIBITION IN MCF-7 BREAST CANCER CELL

    OpenAIRE

    Yi, Xiaofang; Zuo, Jiangcheng; Tan, Chao; Xian, Sheng; Luo, Chunhua; Chen, Sai; Yu, Liangfang; Luo, Yucheng

    2016-01-01

    Background: Kaempferol, a natural flavonoid, has been shown to induce cancer cell apoptosis and cell growth inhibition in several tumors. Previously we have conducted a full investigation on the chemical constituents of Gynura medica, kaempferol and its glycosides are the major constituents of G. medica. Here we investigated the growth inhibition and apoptosis induction effect of kaempferol extracted from G. medica. Materials and Methods: The inhibition effects of kaempferol were evaluated by...

  13. Reuse of worn-out medicaments with adsorbent properties for the removal of manganese

    International Nuclear Information System (INIS)

    Millan C, E.

    2005-01-01

    The current investigations on the treatment of worn-out medicaments in Mexico, reveal that most of these treatments are carried out with the purpose to reduce the packing and diminish the toxic level that presents each one of those medicaments. That it reach to reuse of them is their packing material and/or their cover. Once treated, the worn-out medicaments move to a sanitary filler. With relationship to the investigation works that have been carried out for the manganese removal in solution, they show a great number of materials that they are used for this end, as well as the parameters that influence in the process, such as the concentration of the element, the solution type in that is content and the pH. However, it is not mentioned in none of them the reuse of the worn-out medicaments (Talcid and Melox), as adsorbent materials for the removal of metals from the water. To carry out the present investigation they were selected therefore, to the one Talcid and the Melox because its present adsorbent properties, with the purpose to remove the manganese like water pollutant. Once that the worn-out medicaments were obtained, they put on in contact with different organic solvents, to obtain the active principle, due to the pharmaceutical presentation of the two medicaments that was obtained was in suspension. The active principles of the two medicaments were characterized by means of high vacuum scanning electron microscopy (SEM), elementary microanalysis (EDS) and X-ray diffraction (XRD). The experimental part consisted in putting in contact manganese solutions with the active principles of the worn-out medicaments, varying the time of contact and the concentration. The manganese quantification in the liquid phase carried out by means of atomic absorption spectroscopy (AAS). It was found that the kinetic model that better describes the sorption process of manganese in both worn-out medicaments (Talcid and Melox) it is that of pseudo second order. Those results of

  14. [The research on the edition of Daquanbencao (Complete Collection of Materia Medica)].

    Science.gov (United States)

    Li, Jian; Zhang, Wei; Zhang, Rui-xian

    2009-07-01

    Zhengleibencao (Classified Materia Medica) had been formed into several kinds of edition systems during its dissemination, among which there was the edition system of Daquanbencao (Complete Collection of Materia Medica). Daquanbencao was originally carved in the Jin dynasty, thereafter it was re-carved in the Yuan, Ming and Qing dynasties so as to form a series of editions such as the edition of Zhenyou in the second year of the Jin dynasty; the edition of the Zongwenshuyuan college in Dade renyan year of the Yuan dynasty; the WANG Qiu's carved edition of Shangyitang hall in the Ming dynasty; the carved edition of Jishanshuyuan, the Jishang mountain college in the Ming dynasty, the reprinted edition of PENG Duan-wu in the Ming dynasty, the supplementary edition of YANG Bi-da in the Qing dynasty;, and the carved edition of KE Feng-shi in the Qing dynasty. Among all the editions, Chongkanjingshizhengleidaquanbencao (Reprinted Classified Daquan Materia Medica from Historical Classics) was the representative one. As a representative of the above editions, the carved edition of WANG took the edition of the Zongwenshuyuan college of the Yuan dynasty as the original edition, but the images picture of materia medica adopted from the edition of Zhenghebencao (Materia Medica of the Zhenghe era).

  15. [Textual research on adulteration of Chinese materia medica in ancient China].

    Science.gov (United States)

    Xie, Jin; Wang, De-Qun

    2013-09-01

    By investigating the mainstream works of herbal classics of successive ages, it is found that adulteration of Chinese materia medica appeared early in ancient China. The main methods of adulteration was producing fraud medicines in the Northern-Southern Dynasties, fake medicines began to appear in the Tang Dynasty, and status of adulteration of Chinese materia medica ran unchecked since the Ming and Qing Dynasty. By statistics, there were 76 kinds of adulteration varieties before the Republican period. The main varieties were precious drugs, animal drugs and artifacts. Commonly methods used in the process included forging and adulterating, dealing with 11 kinds and 68 kinds respectively. Adulteration probably lead to the result of imposing the changes of the used medicinal parts of Herba Pogostemonis; Radix Aconiti Lateralis prepared by adding salt, Radix Angelica Sinensis processed by wine, and Radix Astragalis seu Hedysaris processed with bee honey. However, the root cause of adulteration in Chinese materia medica was the dissociation of professional physician and pharmacist, resulting in the ignorance of medical practitioners became unable to recognize Chinese materia medica; and the immorality of medicinal merchants. Besides, rating the quality of materia medica based on its producing areas without differentiating the false from the genuine may also contribute to this result passively.

  16. [Hypothesis and application of bimolecular marking methods in Chinese materia medica].

    Science.gov (United States)

    Huang, Lu-qi; Qian, Dan; Deng, Chao

    2015-01-01

    Based on the current shortage of genuine/false authentication and quality evaluation in the molecular identification, and the weak functional gene research in the establishment of two-dimensional molecular markering methods for Chinese materia medica, the authors proposed a new method, the bimolecular marking methods (BIMM) for Chinese materia medica, combining DNA marker and metabolomics marker, that could simultaneously research the species and quality differences at the molecular level at the present stage. The authors introduced the concept, principle, methods, and technical process of BIMM, and summarized the technical advantages in this paper. Meanwhile, the application of BIMM in the identification of multiple sources of Chinese materia medica, years-identification, different locations, elite germplasm research, discovery of new drugs resources, protection of new varieties was also discussed. As a supplement of two-dimensional molecular markering method for Chinese materia medica, BIMM would not only expand connotation of identification of Chinese materia medica but also provide another effective way for quality evaluating.

  17. Fiche technique du spermogramme et du spermocytogramme ...

    African Journals Online (AJOL)

    En Afrique la stérilité du couple constitue un drame social. Selon l'OMS, environ 8 à 12 % des couples africains sont touchés par une infertilité. La responsabilité masculine dans la stérilité est comprise entre 30 à 40%. Les causes de l'infertilité masculine peuvent être l'impuissance et/ ou l'altération du sperme. L'étude de ...

  18. [Principles for molecular identification of traditional Chinese materia medica using DNA barcoding].

    Science.gov (United States)

    Chen, Shi-Lin; Yao, Hui; Han, Jian-Ping; Xin, Tian-Yi; Pang, Xiao-Hui; Shi, Lin-Chun; Luo, Kun; Song, Jing-Yuan; Hou, Dian-Yun; Shi, Shang-Mei; Qian, Zhong-Zhi

    2013-01-01

    Since the research of molecular identification of Chinese Materia Medica (CMM) using DNA barcode is rapidly developing and popularizing, the principle of this method is approved to be listed in the Supplement of the Pharmacopoeia of the People's Republic of China. Based on the study on comprehensive samples, the DNA barcoding systems have been established to identify CMM, i.e. ITS2 as a core barcode and psbA-trnH as a complementary locus for identification of planta medica, and COI as a core barcode and ITS2 as a complementary locus for identification of animal medica. This article introduced the principle of molecular identification of CMM using DNA barcoding and its drafting instructions. Furthermore, its application perspective was discussed.

  19. Les Cahiers du CREAD

    African Journals Online (AJOL)

    Admin

    politique de bas prix exercée par la Russie et le Qatar vient confirmer ce constat ; s'ajoute à cela l'entrée éventuelle du gaz non conven- tionnel, dont son prix actuel de 3/4 $US, offre aux USA l'opportunité d'être exportateur de ..... les compagnies à produire en matière du gaz naturel, tels le prix du gaz naturel, le prix des ...

  20. Bulletin du CRDI #124

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les femmes jouent un rôle important dans les exploitations minières artisanales et à petite échelle en Afrique subsaharienne. De concert ... Couverture du livre: Une vie saine pour les femmes et les enfants vulnérables · Couverture du livre: Entre el activismo y la intervención · Couverture du livre: Revitalizing Health for All.

  1. Bulletin du CRDI #125

    International Development Research Centre (IDRC) Digital Library (Canada)

    L'IOSRS remporte le prix de la diplomatie scientifique · GrowInclusive : la plateforme tant attendue est en construction · Toutes les nouvelles. Activités à venir. Semaine du développement international 2018. Le CRDI célébrera la Semaine du développement international du 4 au 10 février 2018. Suivez-nous sur Twitter et ...

  2. [The application of metabonomics in modern studies of Chinese materia medica].

    Science.gov (United States)

    Chen, Hai-Bin; Zhou, Hong-Guang; Yu, Xiao-Yi

    2012-06-01

    Metabonomics, a newly developing subject secondary to genomics, transcriptomics, and proteomics, is an important constituent part of systems biology. It is believed to be the final direction of the systems biology. It can be directly applied to understand the physiological and biochemical states by its "metabolome profile" as a whole. Therefore, it can provide a huge amount of information different from those originating from other "omics". In the modernization of Chinese materia medica research, the application of metabonomics methods and technologies has a broad potential for future development. Especially it is of important theoretical significance and application value in holistic efficacies evaluation, active ingredients studies, and safety research of Chinese materia medica.

  3. Variations of 57Fe hyperfine parameters in medicaments containing ferrous fumarate and ferrous sulfate

    International Nuclear Information System (INIS)

    Oshtrakh, M. I.; Novikov, E. G.; Dubiel, S. M.; Semionkin, V. A.

    2010-01-01

    Several commercially available medicaments containing ferrous fumarate (FeC 4 H 2 O 4 ) and ferrous sulfate (FeSO 4 ), as a source of ferrous iron, were studied using a high velocity resolution Mössbauer spectroscopy. A comparison of the 57 Fe hyperfine parameters revealed small variations for the main components in both medicaments indicating some differences in the ferrous fumarates and ferrous sulfates. It was also found that all spectra contained additional minor components probably related to ferrous and ferric impurities or to partially modified main components.

  4. Variations of {sup 57}Fe hyperfine parameters in medicaments containing ferrous fumarate and ferrous sulfate

    Energy Technology Data Exchange (ETDEWEB)

    Oshtrakh, M. I., E-mail: oshtrakh@mail.utnet.ru; Novikov, E. G. [Ural Federal University (The former Ural State Technical University-UPI), Faculty of Physical Techniques and Devices for Quality Control (Russian Federation); Dubiel, S. M. [AGH University of Science and Technology, Faculty of Physics and Computer Science (Poland); Semionkin, V. A. [Ural Federal University (The former Ural State Technical University-UPI), Faculty of Physical Techniques and Devices for Quality Control (Russian Federation)

    2010-04-15

    Several commercially available medicaments containing ferrous fumarate (FeC{sub 4}H{sub 2}O{sub 4}) and ferrous sulfate (FeSO{sub 4}), as a source of ferrous iron, were studied using a high velocity resolution Moessbauer spectroscopy. A comparison of the {sup 57}Fe hyperfine parameters revealed small variations for the main components in both medicaments indicating some differences in the ferrous fumarates and ferrous sulfates. It was also found that all spectra contained additional minor components probably related to ferrous and ferric impurities or to partially modified main components.

  5. "Cirque du Freak."

    Science.gov (United States)

    Rivett, Miriam

    2002-01-01

    Considers the marketing strategies that underpin the success of the "Cirque du Freak" series. Describes how "Cirque du Freak" is an account of events in the life of schoolboy Darren Shan. Notes that it is another reworking of the vampire narrative, a sub-genre of horror writing that has proved highly popular with both adult and…

  6. A new class of medicament: radioactivity isotopes (1962); Une nouvelle classe de medicaments: les isotopes radioactifs (1962)

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, Y. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1962-07-01

    Very many radioelement are used in medicine, either for diagnosis or as therapeutics. The development of medicine has entailed an increase in the number of application of radioactive isotopes. Firstly used in the form of simple inorganic molecules for diagnosis or as anticancer therapeutics, radioelements are now used for labelling organic molecules, allowing functional specific studies of any kind of nature. Their production is made difficult by their radio-active properties. Their pharmaceutical properties, determined by tests and controls, depend either from radiochemistry and from medicine. The author reminds, in this report, the methods for the preparation and analysis, and set out the medical application. (author) [French] De tres nombreux radioelements trouvent une application en medecine humaine, soit dans le diagnostic, soit en therapeutique. L'evolution de la medecine entraine un accroissement du champ d'application des isotopes radioactifs. D'abord utilises sous forme de molecules minerales simples, pour les diagnostics ou des therapeutiques anticancereuses, les radioelements sont maintenant introduits dans des molecules organiques qui permettent des etudes fonctionnelles specifiques de toute nature. Leur fabrication est compliquee par leurs proprietes radioactives. Leurs caracteristiques pharmaceutiques determinees par des essais et controles, sont liees d'une part a la radiochimie, d'autre part a la medecine. L'auteur rappelle, dans cet expose, les methodes de preparation et d'analyse et aborde les applications medicales. (auteur)

  7. A new class of medicament: radioactivity isotopes (1962); Une nouvelle classe de medicaments: les isotopes radioactifs (1962)

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, Y [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1962-07-01

    Very many radioelement are used in medicine, either for diagnosis or as therapeutics. The development of medicine has entailed an increase in the number of application of radioactive isotopes. Firstly used in the form of simple inorganic molecules for diagnosis or as anticancer therapeutics, radioelements are now used for labelling organic molecules, allowing functional specific studies of any kind of nature. Their production is made difficult by their radio-active properties. Their pharmaceutical properties, determined by tests and controls, depend either from radiochemistry and from medicine. The author reminds, in this report, the methods for the preparation and analysis, and set out the medical application. (author) [French] De tres nombreux radioelements trouvent une application en medecine humaine, soit dans le diagnostic, soit en therapeutique. L'evolution de la medecine entraine un accroissement du champ d'application des isotopes radioactifs. D'abord utilises sous forme de molecules minerales simples, pour les diagnostics ou des therapeutiques anticancereuses, les radioelements sont maintenant introduits dans des molecules organiques qui permettent des etudes fonctionnelles specifiques de toute nature. Leur fabrication est compliquee par leurs proprietes radioactives. Leurs caracteristiques pharmaceutiques determinees par des essais et controles, sont liees d'une part a la radiochimie, d'autre part a la medecine. L'auteur rappelle, dans cet expose, les methodes de preparation et d'analyse et aborde les applications medicales. (auteur)

  8. Metabolism of fission products in man: Marshallese experience; Metabolisme des produits de fission radioactifs chez l'homme: donnees recueillies aux iles Marshall; Metabolizm radioaktivnykh produktov deleniya v organizme cheloveka. (dannye obsledovaniya zhite- lej marshal'skikh ostrovov); Metabolismo de productos de fision radiactivos en el hombre: datos obtenidos en los habitantes de las islas Marshall

    Energy Technology Data Exchange (ETDEWEB)

    Cohn, S. H. [Brookhaven National Laboratory, Upton, Long Island, NY (United States)

    1963-02-15

    , produisaient la majeure partie de la dose de rayonnements internes. Apres une annee, les principaux radioisotopes etaient {sup 90}Sr, {sup 137}Cs y {sup 65}Zn. Par la suite, on a mesure periodiquement ces radionucleides et, plus recemment, {sup 60}Co. Depuis 1958, on a pu obtenir, i l'aide d'un appareil portatif de dosage del'activite du corps humain, les spectres gamma d'un certain nombre d'habitants des iles Marshall. L'auteur etudie les resultats de ces enquetes, obtenus au cours des huit dernieres annees. Il presente egalement les resultats d'une tentative faite au debutpour modifier la vitesse d'elimination des produits de fission mixtes chez les autochtones au moyen d'un sel double de calcium et de sodium de l'EDTA. Il etudie enfin le metabolisme des radionucleides et leurs rapports avec les concentrations presentes dans le milieu ambiant. (author) [Spanish] El estudio clinico de los habitantes de las islas Marshall que en 1954 quedaron expuestos accidentalmente a precipitaciones radiactivas posee gran valor cientifico porque, junto con el caso de los pescadores japoneses, constituye la unica fuente de datos sobre el metabolismo de mezclas de productos de fision en el hombre. Al principio, el diagnostico de la contaminacion radiactiva interna se efectuo por analisis radioquimico de los tejidos de animales expuestos simultaneamente. Se encontro que la mayor parte de la dosis de radiacion interna se debia al {sup 89}Sr, {sup 140}Ba, {sup 131}I y sus descendientes de periodo breve, asi como a algunos de los elementos de las tierras raras. Al cabo de un alio,los principales radioisotopos presentes eran el {sup 90}Sr, {sup 137}Cs y {sup 65}Zn. Despues se siguieron midiendo periodicamente estos radionuclidos y, mas recientemente, el {sup 60}Co. Desde 1958, se han obtenido los espectros y de un cierto numero de pobladores de aquellas islas por recuento del organismo entero con un aparato portatil. El informe discute los datos que durante los ultimos ocho anos se han obtenido

  9. Home Delivery Medicament Program: access, inactivity and cardiovascular risk.

    Science.gov (United States)

    Araújo, Roque da Silva; Arcuri, Edna Apparecida Moura; Lopes, Victor Cauê

    2016-10-10

    to verify causes of inactivity in the Home Delivery Medicament Program, as referred by users from a Primary Health Care Service in São Paulo, comparing them to the causes registered in the program and analyzing them in the theoretical model Concept of Access to Health. cross-sectional study, interviewing 111 inactive users; and documentary study in the program records. half of the users did not know the condition of inactivity. Discrepancies were found between the user's and the program's information, observing different levels of agreement: Absence of physician and administrative staff member 0%; Transfer to other service 25%; Death 50%; Option to quit 50%; Address change 57% and Change in therapeutic schedule 80%. The users' feeling of accepting the program was observed. In the health access concept, inactivity can be explained in the information dimension, in the degree of asymmetry between the patient's and the health professional's knowledge, identified through the indicators: education, knowledge and information sources. due to the low education level, the user does not assimilate the information on the steps of the program flowchart, does not return for the assessment that guarantees its continuity. Consequently, (s)he stops receiving the medication and spends a long time without treatment, increasing the cardiovascular risk of hypertensive (92% of the sample), diabetic (44%) and dyslipidemic patients (31%). verificar causas de inatividade no Programa Remédio em Casa, referidas por usuários de Unidade Básica de Saúde de São Paulo, comparando-as às registradas pelo programa e analisando-as no modelo teórico Conceito de Acesso à Saúde. estudo transversal entrevistando 111 usuários inativos; e documental, nos registros do programa. metade dos usuários desconhecia a condição de inatividade. Constatadas discrepâncias nas informações usuário versus programa, observando-se diferentes níveis de concordância: Falta de médico e funcion

  10. Purposing Division Strategy for Pharmaceutical Producer Dexa Medica in the Demanding Market

    Science.gov (United States)

    Setiawati, Cut Irna; Wahyono, Agatha Christy

    2017-01-01

    This research aims to purpose the division strategy for a pharmaceutical producer in Kalimantan area, named Dexa Medica Samarinda. Currently, this firm is facing a competitive market condition and evolving a decline position in the market. This research uses qualitative research method by organising intensive interview to important informants so…

  11. [Revision to origin of northern Artemisia argyi in Compendium of Materia Medica (Bencao gangmu)].

    Science.gov (United States)

    Huang, Lu-qi; Qiu, Le

    2014-12-01

    The origin of northern Artemisia argyi recorded in Compendium of Materia Medica(Bencao gangmu) is Fudao(Chinese characters) in Tangyin county, While there is only Fudao(Chinese characters) instead of Fudao(Chinese characters). Whether indeed Fudao(Chinese characters) is Fudao(Chinese characters)? By reviewing the genuine evolution of A. argyi, doing textual research on Fudao(Chinese characters) and combing with field survey data of national census of Chinese Materia Medica resources, this paper concluded that the word Fudao(Chinese characters) firstly emerged in Figure Canon of Chinese Materia Medica(Bencao tujing) of Susong in Song dynasty and was applied in later generations, but the implication was not clear, then emerged both Tangyin and Fudao(Chinese characters) in Compendium of Materia Medica(Bencao gangmu). The place Fudao(Chinese characters) is one of the graves of Bianque, that existed from Shang and Zhou dynasty and never changed until now, the A. argyi of Tangyin was famous from the grave of Bianque in Fudao(Chinese characters), which could infer that Lishizhen considered Fudao (Chinese characters) was Fudao(Chinese characters) indeed, and the origin of northern A. argyi was Fudao(Chinese characters) in Tangyin county.

  12. [Study on differences between pharmacokinetics and chromatopharmacodynamics for Chinese materia medica formulae].

    Science.gov (United States)

    He, Fuyuan; Deng, Kaiwen; Zou, Huan; Qiu, Yun; Chen, Feng; Zhou, Honghao

    2011-01-01

    To study on the differences between chromatopharmacokinetics (pharmacokinetics with fingerprint chromatography) and chromatopharmacodynamics (pharmacodynamics with fingerprint chromatography) of Chinese materia medica formulae to answer the question whether the pharmacokinetic parameters of multiple composites can be utilized to guide the medication of multiple composites. On the base of established four chromatopharmacology (pharmacology with chromatographic fingerprint), the pharmacokinetics, and pharmacodynamics were analyzed comparably on their mathematical model and parameter definition. On the basis of quantitative pharmacology, the function expressions and total statistical parameters, such as total zero moment, total first moment, total second moment of the pharmacokinetics, and pharmacodynamics were analyzed to the common expressions and elucidated results for single and multiple components in Chinese materia medica formulae. Total quantitative pharmacokinetic, i.e., chromatopharmacokinetic parameter were decided by each component pharmacokinetic parameters, whereas the total quantitative pharmacodynamic, i.e., chromatopharmacodynamic parameter were decided by both of pharmacokinetic and pharmacodynamic parameters of each components. The pharmacokinetic parameters were corresponded to pharmacodynamic parameters with an existing stable effective coefficient when the constitutive ratio of each composite was a constant. The effects of Chinese materia medica were all controlled by pharmacokinetic and pharmacodynamic coefficient. It is a special case that the pharmacokinetic parameter could independently guide the clinical medication for single component whereas the chromatopharmacokinetic parameters are not applied to the multiple drug combination system, and not be used to solve problems of chromatopharmacokinetic of Chinese materia medica formulae.

  13. [Differences of bi-directional regulative effects between acu-moxibustion and Chinese materia medica interventions].

    Science.gov (United States)

    Cao, Xin; Yu, Zhi; Xu, Bin

    2012-10-01

    Bi-directional regulation is referred to a balancing effect of both acu-moxibustion and Chinese materia medica interventions when the human body is experiencing a hyperactivity or hypoactivity due to abnormal intrinsic or external factors. In the present paper, the authors analyze their identical and different characteristics from: 1) definition; 2) characters of regulative effects of acu-moxibustion therapy: A) differentiation of meridian and zangfu-organs being the basis of treatment, B) four factors (acupoint-location, body's functional state, acupoint-formula and needle-manipulation techniques) dependant, C) entirety regulation, and D) centrotaxis modulation; 3) characters of Chinese materia medica intervention: including a) correspondence between the drug property and the syndrome being the basis of the regulative effect, b) multi-factors [components (antagonist and agonist), combination, dosages and processing quality of Chinese materia medica, and functional state of the human body] dependant, c) entirety regulation, and d) both centrotaxis and deviation adjustment. In one word, the bi-directional regulation effect is one of the basic characteristics of both acu-moxibustion and Chinese materia medica in clinical practice, but their basis and modes for inducing effects are different.

  14. New sensor technologies in quality evaluation of Chinese materia medica: 2010-2015.

    Science.gov (United States)

    Miao, Xiaosu; Cui, Qingyu; Wu, Honghui; Qiao, Yanjiang; Zheng, Yanfei; Wu, Zhisheng

    2017-03-01

    New sensor technologies play an important role in quality evaluation of Chinese materia medica (CMM) and include near-infrared spectroscopy, chemical imaging, electronic nose and electronic tongue. This review on quality evaluation of CMM and the application of the new sensors in this assessment is based on studies from 2010 to 2015, with prospects and opportunities for future research.

  15. [Medicaments and oral healthcare 4. Pharmacotherapy in (frail and care dependent) older people].

    NARCIS (Netherlands)

    Baat, C. de; Putten, G.J. van der; Visser, A.; Vissink, A.

    2017-01-01

    Polypharmacy is the consequence of multimorbidity. Both phenomena may cause functional limitations and/or frailty and/or care dependency in older people. In the human body, a medicament undergoes at least 3 important actions: absorption, distribution and elimination. These actions may proceed

  16. [Essential procedure and key methods for survey of traditional knowledge related to Chinese materia medica resources].

    Science.gov (United States)

    Cheng, Gong; Huang, Lu-qi; Xue, Da-yuan; Zhang, Xiao-bo

    2014-12-01

    The survey of traditional knowledge related to Chinese materia medica resources is the important component and one of the innovative aspects of the fourth national survey of the Chinese materia medica resources. China has rich traditional knowledge of traditional Chinese medicine (TCM) and the comprehensive investigation of TCM traditional knowledge aims to promote conservation and sustainable use of Chinese materia medica resources. Building upon the field work of pilot investigations, this paper introduces the essential procedures and key methods for conducting the survey of traditional knowledge related to Chinese materia medica resources. The essential procedures are as follows. First is the preparation phrase. It is important to review all relevant literature and provide training to the survey teams so that they have clear understanding of the concept of traditional knowledge and master key survey methods. Second is the field investigation phrase. When conducting field investigations, survey teams should identify the traditional knowledge holders by using the 'snowball method', record the traditional knowledge after obtaining prior informed concerned from the traditional knowledge holders. Researchers should fill out the survey forms provided by the Technical Specification of the Fourth National Survey of Chinese Materia Medica Resources. Researchers should pay particular attention to the scope of traditional knowledge and the method of inheriting the knowledge, which are the key information for traditional knowledge holders and potential users to reach mutual agreed terms to achieve benefit sharing. Third is the data compilation and analysis phrase. Researchers should try to compile and edit the TCM traditional knowledge in accordance with intellectual property rights requirements so that the information collected through the national survey can serve as the basic data for the TCM traditional knowledge database. The key methods of the survey include regional

  17. Review of the Journal Acta Informatica Medica During Eight Year Period: 2008-2015.

    Science.gov (United States)

    Masic, Izet; Begic, Edin; Zunic, Lejla

    2016-04-01

    Acta Informatica Medica is official journal of the Academy for Medical Sciences of Bosnia and Herzegovina (from 2014 Acta Inform Med is published bimonthly). To evaluate journal "Acta Informatica Medica" in 2015 and compare findings to previous years. The study has retrospective and descriptive character, and included the period 2008-2015 (included 36 issues of journal). A total of 83 (average 13,8 articles per journal) articles were published in Acta Informatica Medica during 2015. Analyzing the type of articles, original articles are present in majority during 2015 (68,6%) (by analyzing last eight years, 310 (67,3%) were original). During 2015, 27,7% of articles were related to the applied of Health informatics in field of clinical medicine, 63,8% preclinical medicine and 8,5% to public health. Collaboration rate in 2015 was 0,84. Most often the time required for decision on acceptance of article in 2015 is between 50 and 60 days. Articles came from 16 countries. According to scimagojr.com for 2014, Acta Informatica Medica has SCImago Journal Rank 0,166, while Cites / Doc. (2 years) parameter (widely used as impact index) is 0,70. According to GoogleScholar, h5 index is 11 and h5 median is 19. We analyzed the Acta Informatica Medica by "Publish or Perish" software - H index was 14, g index was 19 and e-index was 10.39. Year after year the highest number of original articles are published. Although the period of revision of articles is acceptable, the period up to two months is certainly not long, the goal is to reduce this period. Although the magazine in mentioned field found its place, although it is indexed in numerous bases, including: PubMed, PubMed Central, SCOPUS, EMBASE, EBSCO, etc. The main goal for next year is that the magazine becomes part of the Web of Science. Imperative is further internationalization of the magazine.

  18. A comparison of medicinal plant use in Sardinia and Sicily-De Materia Medica revisited?

    Science.gov (United States)

    Leonti, Marco; Casu, Laura; Sanna, Francesca; Bonsignore, Leonardo

    2009-01-21

    Written records of oral medical traditions have had significant impact on the development of medicine and the pharmacopoeias. Modern ethnobotanical studies in Europe and the Mediterranean region, however, have so far largely overlooked the richness and accuracy of historic sources and ignored their probable influence on the development of today's local traditional medicines. Here, we explore the common fundament of traditional knowledge for the medicinal plant uses in Sardinia and Sicily by comparing the selection of medicinal species and specific uses with those of Dioscorides' De Materia Medica. We use (i) a quantification of citations for medicinal species mentioned in ethnobotanical studies conducted in Sardinia and Sicily (ii) a comparison of the flora and medicinal flora with a chi(2)-test (iii) a binomial approach recently introduced into ethnobotany (iv) a comparison of the most frequently used species with the indications cited in Dioscorides' De Materia Medica (v) and a crosscheck of all mentioned species with their appearance in Berendes' translation of De Materia Medica. We identified a core group of 170 medicinal species used on either islands, which accumulate 74% of all citations and are best represented in De Materia Medica. The 15 most frequently used species of both islands demonstrate intriguing parallels for indications with Dioscorides' work. The ethnopharmacopoeia of Sicily and Sardinia are shallow stereotypes of the different editions of De Materia Medica and talking of oral tradition in this respect is a contradiction. The medicinal species of Sardinia and Sicily are largely widespread and common species, including many weeds, which are not facing threat of extinction. Therefore, using traditional medicinal practices as an argument for conservation biology or vice versa is not scientifically sound.

  19. Ecologie du phytoplancton du lac Kivu

    Directory of Open Access Journals (Sweden)

    Sarmento, H.

    2008-01-01

    Full Text Available Speciation within the African Coffee Pathogen. Cet article analyse s'il est avantageux d'utiliser le compost au lieu de l'engrais minéral pour produire la laitue dans la zone urbaine et péri-urbaine de Yaoundé. Les résultats de terrain montrent l'obtention de rendements et profits plus élevés lorsqu'on utilise le compost. Les résultats de la fonction de production Cobb-Douglas prouvent que l'utilisation du compost est statistiquement significative pour expliquer la variation de rendement de la laitue et que le compost est l'intrant le plus productif. D'autres résultats montrent que le compost fournit la matière organique utile au sol et que les besoins d'irrigation en eau de la culture sont réduits grâce à l'utilisation du compost. Par conséquent, malgré le fait que l'application du compost demande une main-d'oeuvre beaucoup plus élevée, son utilisation est généralement bénéfique pour les agriculteurs vivant aux alentours de Yaoundé. Les programmes de vulgarisation de cet intrant pour encourager son adoption devraient donc figurer parmi les points prioritaires dans la politique agricole du gouvernement camerounais.

  20. [Research progress on standards of commodity classes of Chinese materia medica and discussion on several key problems].

    Science.gov (United States)

    Yang, Guang; Zeng, Yan; Guo, Lan-Ping; Huang, Lu-Qi; Jin, Yan; Zheng, Yu-Guang; Wang, Yong-Yan

    2014-05-01

    Standards of commodity classes of Chinese materia medica is an important way to solve the "Lemons Problem" of traditional Chinese medicine market. Standards of commodity classes are also helpful to rebuild market mechanisms for "high price for good quality". The previous edition of commodity classes standards of Chinese materia medica was made 30 years ago. It is no longer adapted to the market demand. This article researched progress on standards of commodity classes of Chinese materia medica. It considered that biological activity is a better choice than chemical constituents for standards of commodity classes of Chinese materia medica. It is also considered that the key point to set standards of commodity classes is finding the influencing factors between "good quality" and "bad quality". The article also discussed the range of commodity classes of Chinese materia medica, and how to coordinate standards of pharmacopoeia and commodity classes. According to different demands, diversiform standards can be used in commodity classes of Chinese materia medica, but efficacy is considered the most important index of commodity standard. Decoction pieces can be included in standards of commodity classes of Chinese materia medica. The authors also formulated the standards of commodity classes of Notoginseng Radix as an example, and hope this study can make a positive and promotion effect on traditional Chinese medicine market related research.

  1. [Important application of intestinal transporters and metabolism enzymes on gastrointestinal disposal of active ingredients of Chinese materia medica].

    Science.gov (United States)

    Bi, Xiaolin; Du, Qiu; Di, Liuqing

    2010-02-01

    Oral drug bioavailability depends on gastrointestinal absorption, intestinal transporters and metabolism enzymes are the important factors in drug gastrointestinal absorption and they can also be induced or inhibited by the active ingredients of Chinese materia medica. This article presents important application of intestinal transporters and metabolism enzymes on gastrointestinal disposal of the active ingredients of Chinese materia medica, and points out the importance of research on transport and metabolism of the active ingredients of Chinese materia medica in Chinese extract and Chinese medicinal formulae.

  2. [Application of bioassay in quality control of Chinese materia medica-taking Radix Isatidis as an example].

    Science.gov (United States)

    Yan, Dan; Ren, Yongshen; Luo, Jiaoyang; Li, Hanbing; Feng, Xue; Xiao, Xiaohe

    2010-10-01

    Bioassay, which construct the characteristics consistents with Chinese medical science, is the core mode and methods for the quality control of Chinese materia medica. Taking the bioassay of Radix Isatidis as an example, the contribution, status and application of bioassay in the quality control of Chinese materia medica were introduced in this article, and two key issue (the selection of reference and measurement methods) in the process of establishing bioassay were also explained. This article expects to provide a reference for the development and improvement of the bioassay of Chinese materia medica in a practical manipulation level.

  3. Du Pont de Nemours

    NARCIS (Netherlands)

    Ros JPM; LAE

    1994-01-01

    Dit rapport over Du Pont de Nemours (produktie van o.a. chemische stoffen) is gepubliceerd binnen het Samenwerkingsproject Procesbeschrijvingen Industrie Nederland (SPIN). In het kader van dit project is informatie verzameld over industriele bedrijven of industriele processen ter ondersteuning

  4. The control of the radioactive pollution of milk (1962); Comment concevoir une surveillance des pollutions radioactives du lait (1962)

    Energy Technology Data Exchange (ETDEWEB)

    Michon, G. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1962-07-01

    Milk, an essential foodstuff, is the object of a supervision and vigilant controls governed by numerous laws which protect its commercial and sanitary qualities. The development of the use of nuclear energy poses and will pose new problems of hygiene and the milk should benefit from controls concerning its possible contamination. Grass-eating animals are particularly subjected to radioactive contaminations and the milk which they produce does not escape contamination because of of its saline composition and of the particular metabolism of the mammary gland. As a result, milk is a contamination integrator and its analysis makes it possible to detect radioelements which can only be detected with great difficulty in an average size plant sample. (author) [French] Le lait, aliment essentiel, fait l'objet d'une surveillance et de controles vigilants regis par de nombreux textes legislatifs qui protegent ses qualites marchandes et sanitaires. Le developpement de l'utilisation de l'energie nucleaire pose et posera de nouveaux problemes d'hygiene et le lait doit beneficier de controles portant sur sa pollution radioactive eventuelle. Les, animaux herbivores sont particulierement exposes aux contaminations radioactives et les laits qu'ils produisent, du fait de leurs compositions salines et du metabolisme particulier de la glande mammaire, n'echappent point aux pollutions. De ce fait, le lait est un integrateur de contamination et son analyse permet de retrouver des radioelements que l'on ne decele qu'avec beaucoup de difficultes sur un echantillon vegetal de taille moyenne. (auteur)

  5. Les Cahiers du CREAD

    African Journals Online (AJOL)

    Admin

    6 juil. 2007 ... La problématique du développement du secteur de l'artisanat en. Algérie a été très peu abordée par les chercheurs, qu'ils soient universitaires ou .... La loi a institué une taxe d'apprentissage dont le taux a été fixé à. 1% de la ...

  6. Les outils du CERN

    CERN Multimedia

    1999-01-01

    C'est le plus grand centre mondial de recherche en physique des particules. Les outils du Laboratoire, accélérateurs et détecteurs de particules, figurent parmi les instruments scientifiques les plus complexes au monde. Des prix Nobels ont d'ailleurs été attribués aux physiciens du CERN pour leurs développements.

  7. Bulletin du CRDI #127

    International Development Research Centre (IDRC) Digital Library (Canada)

    La mise à l'échelle de la recherche et de l'innovation en vue de créer un impact social constitue une priorité pour la communauté du développement. Toutefois ... Nous avons renouvelé notre soutien à la recherche auprès du gouvernement de l'Inde ... Des femmes étudient à l'École supérieure d'infotronique d'Haïti.

  8. [Data validation methods and discussion on Chinese materia medica resource survey].

    Science.gov (United States)

    Zhang, Yue; Ma, Wei-Feng; Zhang, Xiao-Bo; Zhu, Shou-Dong; Guo, Lan-Ping; Wang, Xing-Xing

    2013-07-01

    From the beginning of the fourth national survey of the Chinese materia medica resources, there were 22 provinces have conducted pilots. The survey teams have reported immense data, it put forward the very high request to the database system construction. In order to ensure the quality, it is necessary to check and validate the data in database system. Data validation is important methods to ensure the validity, integrity and accuracy of census data. This paper comprehensively introduce the data validation system of the fourth national survey of the Chinese materia medica resources database system, and further improve the design idea and programs of data validation. The purpose of this study is to promote the survey work smoothly.

  9. [Study on biopharmaceutics classification system for Chinese materia medica of extract of Huanglian].

    Science.gov (United States)

    Liu, Yang; Yin, Xiu-Wen; Wang, Zi-Yu; Li, Xue-Lian; Pan, Meng; Li, Yan-Ping; Dong, Ling

    2017-11-01

    One of the advantages of biopharmaceutics classification system of Chinese materia medica (CMMBCS) is expanding the classification research level from single ingredient to multi-components of Chinese herb, and from multi-components research to holistic research of the Chinese materia medica. In present paper, the alkaloids of extract of huanglian were chosen as the main research object to explore their change rules in solubility and intestinal permeability of single-component and multi-components, and to determine the biopharmaceutical classification of extract of Huanglian from holistic level. The typical shake-flask method and HPLC were used to detect the solubility of single ingredient of alkaloids from extract of huanglian. The quantitative research of alkaloids in intestinal absorption was measured in single-pass intestinal perfusion experiment while permeability coefficient of extract of huanglian was calculated by self-defined weight coefficient method. Copyright© by the Chinese Pharmaceutical Association.

  10. [Recent advances of synthetic biology for production of functional ingredients in Chinese materia medica].

    Science.gov (United States)

    Su, Xin-Yao; Xue, Jian-Ping; Wang, Cai-Xia

    2016-11-01

    The functional ingredients in Chinese materia medica are the main active substance for traditional Chinese medicine and most of them are secondary metabolites derivatives. Until now,the main method to obtain those functional ingredients is through direct extraction from the Chinese materia medica. However, the income is very low because of the high extraction costs and the decreased medicinal plants. Synthetic biology technology, as a new and microbial approach, can be able to carry out large-scale production of functional ingredients and greatly ease the shortage of traditional Chinese medicine ingredients. This review mainly focused on the recent advances in synthetic biology for the functional ingredients production. Copyright© by the Chinese Pharmaceutical Association.

  11. 204: THE ROLE OF IMCI PROGRAM IN THE RATIONALIZATION OF MEDICAMENT USE IN PEDIATRICS

    Science.gov (United States)

    Ahmad, Chreitah

    2017-01-01

    Background and aims Integrated management of childhood illness (IMCI) is an EBM guideline prepared by WHO and UNICEF guideline in primary health care for better assessment and management in pediatrics. The study was carried out to demonstrate the reduction of medicament prescription by the application of IMCI program in two months up to five years old children presenting with an infectious disease. Methods Before and after study was carried out in July 2012 at a pediatric E.R children who met with the inclusion criteria were rolled in: ▸ Consulting for infectious disease. ▸ With no anterior treatment with antibiotics. ▸ No need of hospitalization. In total 112 patients were assessed separately by two groups of doctors (classical approach vs. IMCI guideline). The two prescriptions of each patient were analyzed using Mac Nemar, comparison of proportion tests. Results 112 patients (64 boys, 48 girls) with cough, diarrhea, sore throat, otalgia and fever were studied. In total 280 medicaments were prescribed firstly vs. 160 medicaments with IMCI guideline (P<0.0001). There were 103 oral antibiotics prescribed vs. 28 with IMCI guideline (P<0.0001). There were 20 intra muscular injections prescribed (15 antibiotics) vs. 9 with IMCI guideline (P<0.02). Only 37 antibiotics were justified vs. 82 non-justified (p<0.0001). Conclusion the assessment and management by IMCI program for children age 2 months up to 5 years in outpatient clinic may contribute for a better prescription with a significant reduction in total medicament prescribed, in oral antibiotics and intra muscular injections.

  12. Ten Steps to Improve Quality of the Journal Materia Socio-Medica.

    Science.gov (United States)

    Donev, Doncho M; Masic, Izet

    2017-03-01

    Materia Socio-Medica is one of the oldest public health journals in Europe, established in 1978, and among the most important journals for public health in South-Eastern Europe. The Journal covers all important public health professional, academic and research areas in this field. The aim of the paper is to analyze the journal articles and statistical facts in 2016 and to point out the directions for action and planned further activities for improving the quality of the published papers and visibility of the journal. Review and analysis of documentation and production of the journal, evidence of submitted and rejected manuscripts and published papers in 2016. Total number of 111 articles was published in Materia Socio-Medica during 2016. The most of them were original articles (64,5%). Articles from the fields of Health promotion and prevention were predominant (82,7%), which is one of the primary scope of the journal. Authors of the published articles in 2016 are dispersed to three continents (Europe, Asia and North America) and 15 different countries. The largest number of articles was submitted by authors from the country of origin of the journal, Bosnia and Herzegovina. The acceptance rate of Materia Socioi-Medica in 2016 was 35.7%. Total number of 116 reviewers participated in the manuscript review process in 2016. Materia Socio-Medica will continue to improve the quality of the published papers in 2017 and beyond through education of potential authors, reviewers and Editorial Board members, quality selection of reviewers, supportive editing of articles, and clearly defining instructions and ethical standards of the journal.

  13. Yeast α-Glucosidase Inhibitory Phenolic Compounds Isolated from Gynura medica Leaf

    Directory of Open Access Journals (Sweden)

    Chao Tan

    2013-01-01

    Full Text Available Gynura medica leaf extract contains significant amounts of flavonols and phenolic acids and exhibits powerful hypoglycemic activity against diabetic rats in vivo. However, the hypoglycemic active constituents that exist in the plant have not been fully elaborated. The purpose of this study is to isolate and elaborate the hypoglycemic activity compounds against inhibition the yeast α-glucosidase in vitro. Seven phenolic compounds including five flavonols and two phenolic acids were isolated from the leaf of G. medica. Their structures were identified by the extensive NMR and mass spectral analyses as: kaempferol (1, quercetin (2, kaempferol-3-O-β-D-glucopyranoside (3, kaempferol-3-O-rutinoside (4, rutin (5, chlorogenic acid (6 and 3,5-dicaffeoylquinic acid methyl ester (7. All of the compounds except 1 and 3 were isolated for the first time from G. medica. Compounds 1–7 were also assayed for their hypoglycemic activity against yeast α-glucosidase in vitro. All of the compounds except 1 and 6 showed good yeast α-glucosidase inhibitory activity with the IC50 values of 1.67 mg/mL, 1.46 mg/mL, 0.38 mg/mL, 0.10 mg/mL and 0.53 mg/mL, respectively.

  14. [Design and implementation of data checking system for Chinese materia medica resources survey].

    Science.gov (United States)

    Wang, Hui; Zhang, Xiao-Bo; Ge, Xiao-Guang; Jin, Yan; Jing, Zhi-Xian; Qi, Yuan-Hua; Wang, Ling; Zhao, Yu-Ping; Wang, Wei; Guo, Lan-Ping; Huang, Lu-Qi

    2017-11-01

    The Chinese material medica resources (CMMR) national survey information management system has collected a large amount of data. To help dealing with data recheck, reduce the work of inside, improve the recheck of survey data from provincial and county level, National Resource Center for Chinese Materia Medical has designed a data checking system for Chinese material medica resources survey based on J2EE technology, Java language, Oracle data base in accordance with the SOA framework. It includes single data check, check score, content manage, check the survey data census data with manual checking and automatic checking about census implementation plan, key research information, general survey information, cultivation of medicinal materials information, germplasm resources information the medicine information, market research information, traditional knowledge information, specimen information of this 9 aspects 20 class 175 indicators in two aspects of the quantity and quality. The established system assists in the completion of the data consistency and accuracy, pushes the county survey team timely to complete the data entry arrangement work, so as to improve the integrity, consistency and accuracy of the survey data, and ensure effective and available data, which lay a foundation for providing accurate data support for national survey of the Chinese material medica resources (CMMR) results summary, and displaying results and sharing. Copyright© by the Chinese Pharmaceutical Association.

  15. [Four properties law of nature data of Chinese materia medica in "Chinese herbal medicine (CHM)"].

    Science.gov (United States)

    Yang, Xue-Mei; Lin, Duan-Yi; Lai, Xin-Mei; Chen, Mei-Mei; Huang, Lu-Qi

    2013-05-01

    In order to provide theoretical clues and data support for the use of Chinese medicine clinical drug, experimental study of Chinese materia medica and development of new resources of Chinese materia medica, the four properties as the core, the relationships of property, flavor, channel tropism and toxicity in nature data of Chinese materia medica were analyzed. The spearman rank correlation method was employed to analyze 8 356 Chinese drugs with characteristic of four properties from " Chinese Herbal Medicine" based on data level coding. It was discovered that four properties showed significant positive correlations with tastes of "pungent and sweet" , channels of "spleen" , "stomach" , "kidney" and "toxicity" , but also showed significant negative correlations with tastes of "bitter" and "light" and six channels such as "large intestine" , "heart", "bladder" , "gallbladder" , "small intestine" and "lung" (in descending order of correlation ) (P <0. 01). It was indicated that the more hot the Chinese medicine nature, the more possible it contained "toxicity" , tastes of "pungent" and "sweet" , and the more possible it was belong to channels of "spleen" , "stomach" and "kidney". As well, the more cold the Chinese medicine nature, the more possible it contained tastes of "bitter" and "light", and the more possible it was belong to six channels such as "large intestine", etc.

  16. [Medicaments and oral healthcare 4. Pharmacotherapy in (frail and care dependent) older people].

    Science.gov (United States)

    de Baat, C; van der Putten, G J; Visser, A; Vissink, A

    2017-05-01

    Polypharmacy is the consequence of multimorbidity. Both phenomena may cause functional limitations and/or frailty and/or care dependency in older people. In the human body, a medicament undergoes at least 3 important actions: absorption, distribution and elimination. These actions may proceed aberrantly in older people. Following interaction with receptors, a medicament triggers a chain reaction in the human body. The receptors and each link of the chain reaction may be subject to changes due to diseases as well as ageing. This, particularly, is the case with regard to medications directed towards the central nervous system and the cardiovascular system. Furthermore, interactions may occur between various medications mutually and between medications on the one hand and on the other hand food and water intake, self-medication with herbs, and diseases. Moreover, older people usually experience more adverse effects of medications when compared to younger people. This is due to altered body actions and reactions, polypharmacy and the many possible interactions. In older people, utilisation and intake of medications often give rise to problems that can be divided into medicament-related, patient-related, care- and care provider-related and other problems.

  17. The direct cytotoxic effects of medicaments used in endodontic regeneration on human dental pulp cells.

    Science.gov (United States)

    Labban, Nawaf; Yassen, Ghaeth H; Windsor, L Jack; Platt, Jeffrey A

    2014-12-01

    The purpose of this in vitro study was to evaluate the effects of intracanal medicaments commonly used in endodontic regeneration on the survival of human dental pulp cells (DPCs). DPCs were cultured and exposed to either no medicament treatment or low concentrations (0.3-5 mg ml(-1) ) of calcium hydroxide [Ca(OH)2 ], triple antibiotic paste (TAP), or double antibiotic paste (DAP) for 3 days. After that, toxicity to the DPCs was determined by lactate dehydrogenase activity assays (LDH) and cell proliferation was measured by colorimetric assays (WST-1). Two-way anova followed by Fisher's protected least significant differences was used for statistical analyses (α = 0.05). The group-by-concentration interactions were significant for the LDH and WST-1 assays (P medicaments tested in this study were not cytotoxic in cultured cells. However, these concentrations are much lower than the concentrations that have been advocated in endodontic regeneration. Furthermore, the negative effects of TAP on DPCs were detected at lower concentrations by using the WST-1 assays than by measuring the LDH release. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  18. Use of digital applications in the medicament calculation education for nursing

    Directory of Open Access Journals (Sweden)

    Francisco Gilberto Fernandes Pereira

    Full Text Available Objective.To evaluate the influence of the use of digital applications in medicament calculation education for nursing students. Methods. An experimental study was developed with a sample of 100 nursing students, who were divided randomly into two groups (use of the Calculation Medicines - CalcMed application - available free on the Internet, n=50 and control (conventional method of the calculator use and pre-math skills, n=50. Both groups were assessed before and after the application of the teaching strategy through a test with ten specific questions of medicament calculations. Results. The study group showed a mean score of 8.14 versus an average of 5.02 in the control group. The average time of test execution was faster in the study group compared to the control group (15.7 versus 38.9 minutes. Conclusion. The strategy of using this application positively influences learning and enables greater security in the implementation of medicament calculations.

  19. Comparison of antibacterial efficacy of intracanal medicaments in multiple visit pulpectomies in primary molars-an in vivo study

    Directory of Open Access Journals (Sweden)

    Lele G

    2010-03-01

    Full Text Available Antibacterial efficacy of formocresol, 2% gluteraldehyde and iodine-potassium iodide was assessed by obtaining cultures at consecutive appointments in multiple visit pulpectomies in primary molars. Formocresol and 2% gluteraldehyde were more effective as intracanal medicaments and caused significant reduction in the counts of aerobic and anaerobic microorganisms, thereby supporting the need for placing intracanal medicaments with antibacterial properties, in multiple visit pulpectomies in primary molars.

  20. Effet du Pediococcus acidilactici sur le bilan lipidique sanguin du ...

    African Journals Online (AJOL)

    Les résultats relatifs aux performances zootechniques ont montré que l'addition du probiotique a amélioré significativement le gain de poids pendant la phase de croissance se traduisant par un indice de consommation meilleur. Les dosages du cholestérol total, des triglycérides, du HDL et du LDL ont été déterminés à la ...

  1. Studies on the Utilization, Metabolism and Function of Sterols in the House-Fly, Musca Domestica; Utilisation. Metabolisme et fonctions des sterols chez la mouche domestique (Musca Domestica); Izuchenie usvoeniya, metabolizma i funktsii sterinov v organizme domashnej mukhi Musca Domestica; Estudios sobre la asimilacion, el metabolismo y la funcion de los esteroles in la mosca comun (Musca Domestica)

    Energy Technology Data Exchange (ETDEWEB)

    Robbins, W. E. [United States Department of Agriculture, Agricultural Research Service, Entomology Research Division, Beltsville, MD (United States)

    1963-09-15

    sterols found in the house-fly. (author) [French] On a determine que, de facon generale, les insectes ont besoin de sterols dans leur regime alimentaire pour que leurs larves se developpent et se metamorphosent normalement. Les travaux de l'auteur ont fait apparaitre deux autres fonctions physiologiques des sterols chez la mouche domestique (Musca domestica L.): 1. il est indispensable que le regime alimentaire de la femelle contienne des sterols pour que celle-ci ponde regulierement des oeufs viables; s'il y a carence de sterols, la femelle continue a pondre mais seul un faible pourcentage des oeufs parviennent a eclosion et sont viables; 2. le cholesterol joue egalement un role dans l'utilisation des reserves nutritives dont s'accompagne le debut du developpement des ovaires. On a etudie chez cet insecte les quantites de sterols qui sont necessaires pour que les processus physiologiques ci-dessus se deroulent, ainsi que les transformations metaboliques qui se produisent au cours du developpement, de la metamorphose et de la reproduction. Cette etude a ete faite a l'aide de sterols marques par {sup 14}C et {sup 3}H, en appliquant diverses methodes analytiques: dilution isotopique inversee, chromatographie a phase gazeuse et phase liquide, spectroscopie; on a eu recours a des methodes d'elevage en milieu aseptique et on a etabli des regimes alimentaires semi-controles pour les larves et les adultes. Le cholesterol marque par {sup 14}C et le sitosterol-{beta} marque par {sup 3}H ont ete utilises comme sources de sterols dans le regime alimentaire de la mouche domestique aux stades larvaire et adulte; il s'est revele que l'utilisation et le metabolisme de ces deux sterols etaient a peu pres identiques. Toutefois, on n'a pas observe de transformation du sitosterol- {beta} en cholesterol. Dans le regime alimentaire des larves on a egalement fait entrer du cholesterol en quantite inferieure aux besoins minima et on y a ajoute des ''sterols pauvres'' comme le cholestanol, qui

  2. Les mots du jazz

    OpenAIRE

    Roueff, Olivier

    2007-01-01

    L’ouvrage d’André Schaeffner constitue la première analyse savante du jazz (1926). Il a marqué une étape importante dans le processus de réinvention du jazz en France en contribuant notamment, par sa réception et les polémiques qu’il a suscitées, à transformer l’identification du jazz d’une musique « américaine » à une musique « noire-américaine » (c’est-à-dire aux « racines » africaines). Les analyses proposées dans cet ouvrage, alors qu’elles désignaient des musiques que la critique de jazz...

  3. Ozone impact on vegetation: phenolic metabolism modification and oxidative alteration of Rubisco in Phaseolus vulgaris L; Impact de l'ozone sur le vegetal: modification du metabolisme phenolique et alteration de la Rubisco chez Phaseolus vulgaris L.

    Energy Technology Data Exchange (ETDEWEB)

    Kanoun, M.

    2002-04-15

    In order to characterize and quantify, in semi-natural situation, the incidence of atmospheric pollution on some physiological and metabolic functions in plants, the aim of our work was to identify sub-cellular impact markers, in bean (Phaseolus vulgaris L.), able to characterize a chronic and realistic ozone pollution climate. Two criteria were chosen: the foliar phenolic metabolism and the Rubisco, the key enzyme of photosynthesis. Using Open Top Chambers system, we demonstrated that, according to concentration, exposure kinetic and leaf type, ozone could induce amount variations of some constitutive soluble phenolic and the synthesis of new phenolic (iso-flavonoids). In some cases, these disturbances were observed jointly with foliar injuries and/or biomass reduction. Concurrently, this chronic and moderate ozone exposure could also induce carbonyl formation in amino acid residues constitutive of Rubisco small subunit (Rubisco-SSU) and a reduction in the amount of the native Rubisco. The amount of a constitutive kaempferol glucuronide and the ozone-induced oxidative alteration of Rubisco-SSU were selected and tested for the construction of dose-response relationships. Whatever the marker, the linear model was able to describe the relation. For the phenolic response, several exposure indexes were tested. According to their mode of calculation, these exposure forms emphasize more or less the contribution of high ozone concentrations. If, for Rubisco oxidation, the use of the exposure index AOT40 seems relevant, in the case of the phenolic marker, the choice of the right index is leaf type dependant. (author)

  4. Degradation of a recalcitrant xenobiotic compound: methyl tert-butyl ether (MTBE) metabolism by mycobacterium austroafricanum; Degradation d'un compose xenobiotique recalcitrant: metabolisme du methyl tert-butyl ether (MTBE) par mycobacterium austroafricanum IFP 2012

    Energy Technology Data Exchange (ETDEWEB)

    Francois, A

    2002-11-01

    Methyl tert-butyl ether (MTBE) is introduced up to 15% (vol/vol) in gasoline in order to obtain a good octane number and to prevent carbon monoxide emissions. However, as a consequence of storage tanks leakage, MTBE became one of the major pollutants of aquifers because of its very low biodegradability. The present study aimed at investigating the biodegradation of MTBE by Mycobacterium austroafricanum IFP 2012. The MTBE metabolic pathway was partially elucidated owing to the identification of some intermediates (tert-butyl formate (TBF), tert-butyl alcohol (TBA), a-hydroxy-isobutyric acid and acetone) and some enzymatic activities (MTBE/TBA monooxygenase (non hemic and inducible), TBF esterase, 2-propanol: NDMA oxidoreductase and another monooxygenase involved in acetone degradation). The involvement of TBF and the requirement of cobalt could be explanations for the low natural attenuation of MTBE; whereas the methoxy group does not seem to be implicated. (author)

  5. Degradation of a recalcitrant xenobiotic compound: methyl tert-butyl ether (MTBE) metabolism by mycobacterium austroafricanum; Degradation d'un compose xenobiotique recalcitrant: metabolisme du methyl tert-butyl ether (MTBE) par mycobacterium austroafricanum IFP 2012

    Energy Technology Data Exchange (ETDEWEB)

    Francois, A.

    2002-11-01

    Methyl tert-butyl ether (MTBE) is introduced up to 15% (vol/vol) in gasoline in order to obtain a good octane number and to prevent carbon monoxide emissions. However, as a consequence of storage tanks leakage, MTBE became one of the major pollutants of aquifers because of its very low biodegradability. The present study aimed at investigating the biodegradation of MTBE by Mycobacterium austroafricanum IFP 2012. The MTBE metabolic pathway was partially elucidated owing to the identification of some intermediates (tert-butyl formate (TBF), tert-butyl alcohol (TBA), a-hydroxy-isobutyric acid and acetone) and some enzymatic activities (MTBE/TBA monooxygenase (non hemic and inducible), TBF esterase, 2-propanol: NDMA oxidoreductase and another monooxygenase involved in acetone degradation). The involvement of TBF and the requirement of cobalt could be explanations for the low natural attenuation of MTBE; whereas the methoxy group does not seem to be implicated. (author)

  6. Integrated approach of the metabolism and the muscle perfusion in imaging and magnetic resonance spectroscopy; Approche integree du metabolisme et de la perfusion musculaire en imagerie et spectroscopie par resonance magnetique nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Brillault-Salvat, C

    1997-12-16

    Oxygen is necessary to the tissue life. Every step from its transport of the ambient medium to its consumption by cells are essential to the right functioning of organism. The involved phenomena are complex and use numerous different mechanisms. In order to better understand the functioning, it has been developed a non traumatic, non irradiating and quantitative method that allows to measure in the same time several determinants of the tissue oxygenation. (N.C.)

  7. fibrosarcome du larynx

    African Journals Online (AJOL)

    pie du lit tumoral est employée comme complément thé- rapeutique [9] alors que la chimiothérapie est générale- ment indiquée dans les formes métastatiques. Le pronos- tic dépend essentiellement du degré de différentiation his- tologique. En fait, le fibrosarcome bien différencié est caractérisé par la fréquence de récidive ...

  8. du Chott Marouane

    African Journals Online (AJOL)

    plancton de 90 µm de vide de maille. Ils ont été conservés dans du formol à 5%. L'identification de l'espèce est basée sur des critères morphologiques [20]: la forme des furcas, les lobes frontaux des antennes des mâles, de l'organe copulateur (pénis) et du sac ovigère. Le comptage des soies furcales a été réalisé. L'étude ...

  9. les cahiers du cread

    African Journals Online (AJOL)

    Our Journal “les cahiers du cread” is a quarterly economic review publishing original findings of empirical research and theoretical debates on fields pertaining to our mission coverage (Macro Economics, Industrial Economics and Firms, Human Development & Social Economics, Agriculture & Environment). Other websites ...

  10. [Preliminary investigation on the materia medica of the Zhuang ethnic group].

    Science.gov (United States)

    Rong, Xiao-Xiang; Li, Gui

    2013-09-01

    By Zhuang materia medica, it refers to application of medicines under the instructions of medical theory of Zhuang ethnic group. By studying the pronunciation of the Zhuang language for the terms "zhu yu", "bai jiu", and "mi gu" included in the shan hai jing nan shan jing (The Classic of Southern Mountain in Classic of Seas and Mountains) carried out by the Zhuang scholar Qin Bao-lin, it was concluded that the Zhuang minority already applied medicines early in the pre-Qin period. Through extensive cultural communication in different regions in the Wei-Jin-Southern-Northern Dynasties, the medicinal experiences of the Zhuang ethnic group appeared in ancient literature. The antidotes in Zhou hou fang (Handbook of Prescriptions for Emergency), for instance, were mostly coming from the Southern Ridge area. Since the Sui-Tang Dynasties, many materia medica recorded in the herbal works and regional gazetteers, and Annals such as the Guangxi Annals, Gazetteer of Nanning County, and Gazetteer of Liuzhou County, Gazetteer of Binzhou County etc., also carry medicines such as Cinnamom twigs and bark, and mangosteen etc., which are similar to those of the Zhuang medicines. In the Republican period, many manuscripts of Zhuang medicines appeared. After 1949, many institutions of Zhuang medicine were set up successively, including The Nanning Medical Institute, The Medical Institute of Wuzhou, The Medical Institute of Guilin. Systematic researches were also done, with publication of a series of works on Zhuang materia medica. Reformation of part of the prescription forms of Zhuang medicine were also accomplished.

  11. Robotica medica

    OpenAIRE

    Di Martino, Assunta

    2017-01-01

    Tra la vasta area della cosiddetta “robotica dei servizi” un settore sempre più importante e destinato a crescere enormemente è quello dei robot usati in campo medico, in particolare per le operazioni chirurgiche di grande precisione. L’idea di applicare le tecnologie robotiche alla chirurgia prende corpo nella seconda metà degli anni 90 con lo scopo precipuo di sostituire l’intervento umano in situazioni di guerra o calamità( ). Oggi un sistema robotico può ricoprire vari ruoli funzionali in...

  12. Advance in quality assessment of Chinese materia medica using microscopic and morphological methods.

    Science.gov (United States)

    Miao, Xiao-Su; Cui, Qing-Yu; Wang, Zhao-Yi; Liu, Xiao-Na; Zhao, An-Bang; Qiao, Yan-Jiang; Wu, Zhi-Sheng

    2017-09-01

    Quality evaluation plays a vital role in ensuring safety and effectiveness of Chinese materia medica (CMM). Microscopic and morphological technologies can be used to distinguish CMM's characteristics, such as shape, size, texture, section, and smell, for authenticity and quality control of CMM. The microscopic and morphological applications of novel micro-technology, colorimeter, and texture analyzer for CMM identification are summarized and the future prospect is discussed in this paper. Various styles and complex sources of CMM are systemically reviewed, including cormophyte medicinal materials, fruit and seeds, pollen grain, and spore materials. Copyright © 2017 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.

  13. Medical Business Ethics in the XXI century; Deontologia medica del siglo XXI

    Energy Technology Data Exchange (ETDEWEB)

    Moya Pueyo, V.

    2009-07-01

    Since ancient times the medical professional practice included moral rules in order to assure a correct approach of capital problems. These rules evolve and are now gathered in the Deontological Codes watching the Constitution and other higher Laws. There has been an increase of interest for none strictly clinical matter since the appearance of the term Bioethics. The book Deontologia medica en el siglo XXI tackles problems of first interest in the present times, thru statistics and analysis, trying to help the medical doctors that have to take ethic decisions. (Author)

  14. [The translation and its meanings of Materia Medica Part. I in the Jejungwon].

    Science.gov (United States)

    Park, Junhyoung; Park, Hyoungwoo

    2011-12-31

    For more systematic medical education, Dr. O. R. Avison translated medical textbooks into Korean since he took charge of Jejungwon in 1893. The first book he chose was Anatomy of the Human Body. He, however, failed to see it published after losing its manuscript twice. Instead, Materia Medica Part. I was brought into the world first in 1905, for which he translated Materia Medica and Therapeutics written by John Mitchell Bruce from the U. K. At that time, this book was in widespread use in the English-speaking world as a textbook for pharmacology. It is also assumed that Avison used it as a textbook for his classes in Canada before coming to Korea. For the publication of Materia Medica Part. I, Avison did not translate Bruce's original text in full, but translated only the selected passages. He followed a principle of using Korean alphabets (Hangeul) only, but in combination with Chinese characters, if necessary. He put pharmacological terms into existing Korean equivalents or newly coined words, but also borrowed many from Japanese terms. That's because Japan moved faster to introduce Western medicine than Korea did, so that many pharmacological terms could be defined and arranged more systematically in Japanese. Moreover, Japan took such a favorable stance in the state of international affairs that many of Japanese-style terms could be introduced into Korea in most fields including medicine. By translating Materia Medica Part. I in cooperation with his disciple KIM Pilsoon after Gray's Anatomy of the Human Body, Avison tried to lay groundwork for providing medical education in Korea based on the British-American medicine. It is assumed that he took an independent stance in selecting and translating Western medical textbooks on his own rather than simply accepting the existing Chinese translation of Western medical textbooks. Despite all his efforts, he might find it difficult to translate all the Western medical terms into Korean within a short period of time

  15. [Current situation of toxicity classification of Chinese materia medica and its research thoughts].

    Science.gov (United States)

    Sun, Wenyan; Hou, Xiujuan; Wang, Bin; Zhu, Yuelan; Zhang, Shuofeng; Chang, Hongsheng; Sun, Jianning

    2012-08-01

    Toxicity of Chinese materia medica (CMM) is an important part of Chinese herbal nature theory. In clinical application, the dosage, time limitation and compatibility of CMM is mainly determined by toxicity. At present, there is no uniform toxicity classification standard for the evaluation of Chinese herbal toxicity. Therefore, it is significant to research toxicity classification of CMM. The current situation of toxicity classification of CMM is reviewed in this paper, and proposed research thoughts are as follows: the measurement of toxicity parameters, the confirmation of poisoning target organs, the investigation on toxic mechanism by serum pharmacology and toxicokinetics, the comprehensive evaluation on toxicity based on quantitative theory.

  16. Comparaison du filtre adaptatif RIF et du filtre a base de reseau de ...

    African Journals Online (AJOL)

    Comparaison du filtre adaptatif RIF et du filtre a base de reseau de neurones pour le filtrage du courant de reference pour la commande du filtre actif parallele. C Benachaiba, A Bassou, B Mazari ...

  17. Le ministre du Commerce international du Canada rencontre des ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    17 juil. 2017 ... La promotion de l'entrepreneuriat, la façon dont le commerce peut profiter aux femmes et à leur famille, et la création d'emplois pour les plus vulnérables étaient au coeur de la discussion en table ronde du ministre du Commerce international du Canada, l'honorable François-Philippe Champagne, et des ...

  18. Bacteriological evaluation of Allium sativum oil as a new medicament for pulpotomy of primary teeth.

    Science.gov (United States)

    Mohammad, Shukry Gamal; Baroudi, Kusai

    2015-01-01

    To compare the effects of Allium sativum oil and formocresol on the pulp tissue of the pulpotomized teeth. Twenty children were selected for this study. All children had a pair of non-vital primary molars. A sterile paper point was dipped in the root canals prior to the mortal pulpotomy. These paper points were collected in transfer media and immediately transported to the microbiological lab to be investigated microbiologically (for Streptococcus mutans and Lactobacillus acidophilus). Then the procedure of mortal pulpotomy was performed. After 2 weeks, the cotton pellets were removed and sterile paper points were dipped in the root canals for microbiological examination. Then comparison between the count of bacteria before and after treatment was conducted. Statistical analysis was performed using independent t-test and paired t-test at the significance level of α = 0.05. After application of both medicaments, there was a marked decrease in S. mutans and L. acidophilus counts. The difference between the mean of log values of the count before and after the application was highly significant for both medicaments (P sativum oil was used. A. sativum oil had more powerful antimicrobial effects than formocresol on the bacteria of the infected root canals.

  19. Pectin extraction from Citron peel (Citrus medica Linn. and its use in food system

    Directory of Open Access Journals (Sweden)

    Rojanakorn, T.

    2006-11-01

    Full Text Available Screening experiments using 25-1 fractional factorial design showed that pH, temperature, and extracting time were the main factors affecting the amount and quality of extracted pectin from Citrus medica Linn. Optimum condition of pectin extraction was studied using central composite design (CCD. Mathematical models relating pH, temperature and extracted time to amount of extracted pectin, equivalent weight, methyl content and anhydrogalacturonic acid content were established. Based on the mathematics models, the condition of pH 2, 100ºC and 105 min was found to be the optimum conditions for pectin extraction from Citrus medica Linn. Mathematical and experimental results were verified. The use of extracted pectin as a gelling agent in pineapple jam revealed no significant difference in gel consistency compared to that of commercial pectin grade 150 (p>0.05. However, the commercial pectin had a higher liking score on the spreadability, texture and overall liking. As a stabilizer in chocolate pasteurised milk, 0.2% of the extracted pectin was required to prevent precipitation of chocolate powder with the similar viscosity obtained from 0.06% κ-carageenan

  20. The role of medicaments, exosomes and miRNA molecules in modulation of macrophage immune activity

    Directory of Open Access Journals (Sweden)

    Katarzyna Nazimek

    2015-01-01

    Full Text Available Macrophages play an important role in innate immunity, in induction and orchestration of acquired immune response as well as in the maintenance of tissue homeostasis. Macrophages as antigen presenting cells induce or inhibit the development of immune response and as effector cells play an important role in innate immunity to infectious agents and in delayed--type hypersensitivity as well. Thus, either up- or down-regulation of their activity leads to the impairment of different biological processes. This often results in the development of immunological diseases or inflammatory response associated with metabolic, cardiovascular or neuroendocrine disorders. Therefore, the possibility of modulation of macrophage function should allow for elaboration of new effective therapeutic strategies. Noteworthy, interaction of medicaments with macrophages may directly mediate their therapeutic activity or is an additional beneficial effect increasing efficacy of treatment. Further, macrophage differentiation is regulated by miRNA-223, while expression of miRNA-146 and miRNA-155 may modulate and/or be a result of the current cell phenotype. Present review is focused on the current knowledge about the action of medicaments, microRNA molecules, exosomes and related vesicles on macrophages leading to modulation of their biological activity.

  1. [History and development of carbonization of Chinese materia medica and exploration on its mechanism of hemostatic action].

    Science.gov (United States)

    He, R J; Diao, T M; DU, D

    2017-03-28

    The first material recorded about hair charcoal is seen in Nei jing ( Inner Canon ). It has a history of over 2 000 years for the carbonization of Chinese materia medica. There were controversies on this matter and its clinical application was seldom seen and underdeveloped. After the Yuan Dynasty, the main theory of carbonic herbs for hemostasis, and keeping the nature of the medicines after carbonization was gradually formed, and physicians of generations began to conduct in-depth research. Through repeated practice and verification, people summed up the suitable species of Chinese materia medica and its principle for carbonization. The methods and degree of carbonization of Chinese materia medica are reasonably discussed, with its principle and basis for application primarily interpreted.

  2. Portage vaginal du streptocoque du groupe B chez la femme ...

    African Journals Online (AJOL)

    Introduction: le streptocoque du groupe B est le principal agent impliqué dans les infections materno-fœtales, les septicémies et les méningites du nouveau-né à terme. L'objectif est de déterminer le taux de portage maternel du streptocoque du groupe B (SGB) à terme. Méthodes: un prélèvement vaginal a été réalisé de ...

  3. Aux origines du monde

    CERN Multimedia

    2004-01-01

    "C'est l'histoire d'une aventure humaine, scientifique, international qui a vu le jour il y a cinquante ans, aux confins de la Suisse et du département de l'Ain. Le plus grand laboratoire de physique des particules du monde, le Cern, a été fondé en 1954. Les festivités organisées à l occasion de cet anniversaire connaîtront leur point d'orgue le 16 octobre prochain, avec portes-ouvertes, accueil de personallités et inauguration d'un monumnet spécifique, le Globe de l'innovation" (2 pages)

  4. CHOEUR DU CERN

    CERN Multimedia

    CHOEUR DU CERN

    2010-01-01

    Les répétitions du chœur du CERN reprendront le mercredi 15 septembre à 20.00 heures à l’amphithéâtre principal – bâtiment 500. Au programme la préparation de notre concert de Noël avec la Missa Brevis, KV115, de Léopold Mozart et de la musique de Noël d’Europe. Les personnes qui aiment chanter, notamment des sopranes et des ténors, sont les bienvenues. Pour tout contact s’adresser à : Baudouin Bleus - (tél.CERN 767 82 44) -(baudouin.bleus@cern.ch) ou Martin Gatehouse ( martin.gatehouse@wanadoo.fr) ou Jean-Paul Diss (jean-pauldiss@wanadoo.fr).  

  5. Hepatiques du Surinam

    NARCIS (Netherlands)

    Jovet-Ast, S.

    1957-01-01

    Il n’existe pas, actuellement, de catalogue des Hépatiques du Surinam. Les Hépatiques de ce pays restent très peu connues. Cependant, certaines ont attiré l’attention des Bryologues et ont été citées dans quelques ouvrages anciens ou récents. Je ne ferai pas ici une révision complète de ces

  6. (l.) Medik du Maroc

    African Journals Online (AJOL)

    PR BOKO

    Résumé. Dipcadi serotinum (L.) Medik, est une plante de la famille des Hyacinthaceae, elle est largement utilisée comme réchauffant et aussi pour combattre la jaunisse. Cette plante trouve une large utilisation par la population de la région côtière du Maroc. À notre connaissance l'huile essentielle de cette espèce n'a ...

  7. Identification of species and materia medica within Angelica L. (Umbelliferae) based on phylogeny inferred from DNA barcodes.

    Science.gov (United States)

    Yuan, Qing-Jun; Zhang, Bin; Jiang, Dan; Zhang, Wen-Jing; Lin, Tsai-Yun; Wang, Nian-He; Chiou, Shu-Jiau; Huang, Lu-Qi

    2015-03-01

    DNA barcodes have been increasingly used in authentication of medicinal plants, while their wide application in materia medica is limited in their accuracy due to incomplete sampling of species and absence of identification for materia medica. In this study, 95 leaf accessions of 23 species (including one variety) and materia medica of three Pharmacopoeia-recorded species of Angelica in China were collected to evaluate the effectiveness of four DNA barcodes (rbcL, matK, trnH-psbA and ITS). Our results showed that ITS provided the best discriminatory power by resolving 17 species as monophyletic lineages without shared alleles and exhibited the largest barcoding gap among the four single barcodes. The phylogenetic analysis of ITS showed that Levisticum officinale and Angelica sinensis were sister taxa, which indicates that L. officinale should be considered as a species of Angelica. The combination of ITS + rbcL + matK + trnH-psbA performed slight better discriminatory power than ITS, recovering 23 species without shared alleles and 19 species as monophyletic clades in ML tree. Authentication of materia medica using ITS revealed that the decoction pieces of A. sinensis and A. biserrata were partially adulterated with those of L. officinale, and the temperature around 80 °C processing A. dahurica decoction pieces obviously reduced the efficiency of PCR and sequencing. The examination of two cultivated varieties of A. dahurica from different localities indicated that the four DNA barcodes are inefficient for discriminating geographical authenticity of conspecific materia medica. This study provides an empirical paradigm in identification of medicinal plants and their materia medica using DNA barcodes. © 2014 The Authors. Molecular Ecology Resources Published by John Wiley & Sons Ltd.

  8. La mesure du danger

    CERN Document Server

    Manceron, Vanessa; Revet, Sandrine

    2014-01-01

    La mesure du danger permet d’explorer des dangers de nature aussi diverse que la délinquance, la pollution, l’écueil maritime, la maladie ou l’attaque sorcellaire, l’extinction d’espèces animales ou végétales, voire de la Planète tout entière. Au croisement de la sociologie, de l’anthropologie et de l’histoire, les différents articles analysent les pratiques concrètes de mesure pour tenter de comprendre ce qui se produit au cours de l’opération d’évaluation du danger sans préjuger de la nature de celui-ci. L’anthropologie a contribué à la réflexion sur l’infortune en s’intéressant aux temporalités de l’après : maladies, catastrophes, pandémies, etc. et en cherchant à rendre compte de l’expérience des victimes, de leur vie ordinaire bouleversée, de la recomposition du quotidien. Elle s’intéresse aussi aux autres types de mesures, les savoirs incorporés, qui reposent sur l’odorat, la vue ou le toucher et ceux qui ressortent d’une épistémologie « non ...

  9. Authentication of Chinese Materia Medica decoction dregs. Part II: comparison before and after decoction of four Chinese Materia Medica that mainly comprise storage tissue.

    Science.gov (United States)

    Wong, Lailai; Liang, Zhitao; Chen, Hubiao; Zhao, Zhongzhen

    2012-02-01

    Authentication of Chinese Materia Medica (CMM) decoction dregs is important for ensuring the efficacy and safety of CMM when they are used in decoction. If someone got worse or poisoned after taking a decoction while the formula is appropriate, the authentication of CMM dregs is the effective method to explore the reasons. Therefore, a systematic study on the authentication of CMM dregs was carried out. In this study, two pairs of easily confused CMM dregs, Fenge (Puerariae Thomsonii Radix) and Shanyao (Dioscoreae Rhizoma), Dihuang (Rehmanniae Radix) and Huangjing (Polygonati Rhizoma), which mostly comprise storage tissues, were investigated by comparing the morphological and microscopic characteristics. Fenge and Shanyao contain abundant starch granules. After decoction their dregs were hard, nonstarchy and horn-like. Fully gelatinized starch granules were found in the powder of Fenge dregs while incompletely gelatinized starch granules were occasionally found in the Shanyao dregs. In contrast, Dihuang and Huangjing contain water-soluble sugars. After decoction, their dregs were hard and brittle. Their parenchymatous cells were shrunken and unknown crystals were found under microscope. Hence, the morphological and microscopic characteristics of CMM before and after decoction were different, and different changes in the CMM dregs can be illustrated by the different nature of their ergastic substance. These differences could be used to authenticate CMM dregs. Copyright © 2011 Wiley Periodicals, Inc.

  10. [New materia medica project: synthetic biology based bioactive metabolites research in medicinal plant].

    Science.gov (United States)

    Wang, Yong

    2017-03-25

    In the last decade, synthetic biology research has been gradually transited from monocellular parts or devices toward more complex multicellular systems. The emerging plant synthetic biology is regarded as the "next chapter" of synthetic biology. The complex and diverse plant metabolism as the entry point, plant synthetic biology research not only helps us understand how real life is working, but also facilitates us to learn how to design and construct more complex artificial life. Bioactive compounds innovation and large-scale production are expected to be breakthrough with the redesigned plant metabolism as well. In this review, we discuss the research progress in plant synthetic biology and propose the new materia medica project to lift the level of traditional Chinese herbal medicine research.

  11. [Key content and formulation of national Chinese materia medica resources survey at county level].

    Science.gov (United States)

    Lu, Jian-Wei; Zhang, Xiao-Bo; Li, Hai-Tao; Guo, Lan-Ping; Zhao, Run-Huai; Zhang, Ben-Gang; Sun, Li-Ying; Huang, Lu-Qi

    2013-08-01

    According to National Census for Water, National Population Census, National Land and Resources Survey, and work experience of experimental measures for national Chinese materia medica resources(CMMR) survey,the national CMMR survey at the county level is the key point of whole survey, that includes organization and management, field survey, sorting data three key links. Organization and management works of national CMMR survey needs to finish four key contents, there are definite goals and tasks, practicable crew, preparation directory, and security assurance. Field survey works of the national CMMR survey needs to finish five key contents, there are preparation works for field survey, the choice of the key survey area (samples), fill in the questionnaire, video data collection, specimen and other physical collection. Sorting data works of the national CMMR survey needs to finish tree key contents, there are data, specimen and census results.

  12. [Formulation of technical specification for national survey of Chinese materia medica resources].

    Science.gov (United States)

    Guo, Lan-Ping; Lu, Jian-Wei; Zhang, Xiao-Bo; Zhao, Run-Huai; Zhang, Ben-Gang; Sun, Li-Ying; Huang, Lu-Qi

    2013-04-01

    According to the process of the technical specification (TS) design for the fourth national survey of the Chinese materia medica resources (CMMR), we analyzed the assignment and objectives of the national survey and pointed out that the differences about CMMR management around China, the distribution of CMMR and their habitat, the economic and technological level, and even enthusiasm and initiative of the staff, etc. are the most difficult points for TS design. And we adopt the principle of combination of the mandatory and flexibility in TS design. We fixed the key points which would affect the quality of national survey first, then proposed the framework of TS which including 3 parts of organization and 11 parts of technique itself. The framework will serve and lead the TS preparation, which will not only provide an action standard to the national survey but will also have a profound influence to the popularization and application of the survey technology of CMMR. [Key words

  13. PAT: From Western solid dosage forms to Chinese materia medica preparations using NIR-CI.

    Science.gov (United States)

    Zhou, Luwei; Xu, Manfei; Wu, Zhisheng; Shi, Xinyuan; Qiao, Yanjiang

    2016-01-01

    Near-infrared chemical imaging (NIR-CI) is an emerging technology that combines traditional near-infrared spectroscopy with chemical imaging. Therefore, NIR-CI can extract spectral information from pharmaceutical products and simultaneously visualize the spatial distribution of chemical components. The rapid and non-destructive features of NIR-CI make it an attractive process analytical technology (PAT) for identifying and monitoring critical control parameters during the pharmaceutical manufacturing process. This review mainly focuses on the pharmaceutical applications of NIR-CI in each unit operation during the manufacturing processes, from the Western solid dosage forms to the Chinese materia medica preparations. Finally, future applications of chemical imaging in the pharmaceutical industry are discussed. Copyright © 2015 John Wiley & Sons, Ltd.

  14. [Academic heritage of Jiu huang ben cao (Materia Medica for Relief of Famines) in Japan].

    Science.gov (United States)

    He, Huiling; Xiao, Yongzhi

    2014-11-01

    Jiu huang ben cao (Materia Medica for Relief of Famines) was the first monograph on famines herbal in the history of China, which creates a new research field of edible plants. Around the middle and late 17th century, Jiu huang ben cao was spread to Japan and aroused great attention of famous Japanese herbalists. Thus, all versions of different edition systems were circulated in Japan. Later, some famous Japanese scholar ssuccessively quoted texts of Jiu huang ben cao from the Nong zheng quan shu (Whole book on Agricultural Administration) spread in Japan, and block-printed it as an independent work. As a result, Jiu huang ben cao virtually circulated widely in Japan.

  15. [Impacts of multicomponent environment on solubility of puerarin in biopharmaceutics classification system of Chinese materia medica].

    Science.gov (United States)

    Hou, Cheng-Bo; Wang, Guo-Peng; Zhang, Qiang; Yang, Wen-Ning; Lv, Bei-Ran; Wei, Li; Dong, Ling

    2014-12-01

    To illustrate the solubility involved in biopharmaceutics classification system of Chinese materia medica (CMMBCS) , the influences of artificial multicomponent environment on solubility were investigated in this study. Mathematical model was built to describe the variation trend of their influence on the solubility of puerarin. Carried out with progressive levels, single component environment: baicalin, berberine and glycyrrhizic acid; double-component environment: baicalin and glycyrrhizic acid, baicalin and berberine and glycyrrhizic acid and berberine; and treble-component environment: baicalin, berberin, glycyrrhizic acid were used to describe the variation tendency of their influences on the solubility of puerarin, respectively. And then, the mathematical regression equation model was established to characterize the solubility of puerarin under multicomponent environment.

  16. [Real-time detection of quality of Chinese materia medica: strategy of NIR model evaluation].

    Science.gov (United States)

    Wu, Zhi-sheng; Shi, Xin-yuan; Xu, Bing; Dai, Xing-xing; Qiao, Yan-jiang

    2015-07-01

    The definition of critical quality attributes of Chinese materia medica ( CMM) was put forward based on the top-level design concept. Nowadays, coupled with the development of rapid analytical science, rapid assessment of critical quality attributes of CMM was firstly carried out, which was the secondary discipline branch of CMM. Taking near infrared (NIR) spectroscopy as an example, which is a rapid analytical technology in pharmaceutical process over the past decade, systematic review is the chemometric parameters in NIR model evaluation. According to the characteristics of complexity of CMM and trace components analysis, a multi-source information fusion strategy of NIR model was developed for assessment of critical quality attributes of CMM. The strategy has provided guideline for NIR reliable analysis in critical quality attributes of CMM.

  17. [Design and implementation of mobile terminal data acquisition for Chinese materia medica resources survey].

    Science.gov (United States)

    Qi, Yuan-Hua; Wang, Hui; Zhang, Xiao-Bo; Jin, Yan; Ge, Xiao-Guang; Jing, Zhi-Xian; Wang, Ling; Zhao, Yu-Ping; Guo, Lan-Ping; Huang, Lu-Qi

    2017-11-01

    In this paper, a data acquisition system based on mobile terminal combining GPS, offset correction, automatic speech recognition and database networking technology was designed implemented with the function of locating the latitude and elevation information fast, taking conveniently various types of Chinese herbal plant photos, photos, samples habitat photos and so on. The mobile system realizes automatic association with Chinese medicine source information, through the voice recognition function it records the information of plant characteristics and environmental characteristics, and record relevant plant specimen information. The data processing platform based on Chinese medicine resources survey data reporting client can effectively assists in indoor data processing, derives the mobile terminal data to computer terminal. The established data acquisition system provides strong technical support for the fourth national survey of the Chinese materia medica resources (CMMR). Copyright© by the Chinese Pharmaceutical Association.

  18. Archives: les cahiers du cread

    African Journals Online (AJOL)

    Items 1 - 24 of 24 ... Archives: les cahiers du cread. Journal Home > Archives: les cahiers du cread. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 24 of 24 Items. 2016 ...

  19. Le commerce du Nord

    OpenAIRE

    Pourchasse, Pierrick; Bouëdec, Gérard Le

    2015-01-01

    Au XVIIIe siècle, la France s'approvisionne abondamment dans les pays du Nord : bois, chanvre et goudron de la Baltique, tonnellerie de Poméranie, pêche de rogue de Norvège, graines de lin de Courlande, barres de fer suédois… Sa balance commerciale est pourtant positive grâce aux sels, aux vins et surtout des nouvelles marchandises coloniales. Or, la plupart des transactions passent par l’incontournable intermédiaire hollandais. Les explications sur l’absence des Français dans le Nord sont re...

  20. La voie du Centre

    OpenAIRE

    2017-01-01

    Après avoir quelque peu louvoyé dans un discours apparemment anarchique où les souvenirs semblent se bousculer sans autre fil conducteur que la référence obsédante au mal satanique, brusquement le narrateur annonce un événement primordial : Foi um fato que se deu, um dia, se abriu. O primeiro. Depois o senhor verá por quê, me devolvendo minha razão (79). Cette introduction situe la rencontre du Menino comme fondatrice d’un destin dont il reviendrait au narrataire de dégager les enchaînements....

  1. Bulletin du CRDI #126

    International Development Research Centre (IDRC) Digital Library (Canada)

    26 févr. 2018 ... Dans ce numéro, découvrez comment la recherche financée par le CRDI permet d'améliorer la santé des mères et des enfants dans les pays du Sud et comment les innovations techniques et sociales de l'initiative SEARCH permettent de surmonter les défis liés à la cybersanté. N'oubliez pas non plus de ...

  2. [Study and comparison on HPLC fingerprints of flavonoids of frequently used Chinese materia medica in citrus].

    Science.gov (United States)

    Chen, Yonggang; Lin, Li

    2011-10-01

    To establish the HPLC fingerprint of flavonoids of the six clinical frequently used Chinese materia medica for regulating Qi flow,such as Citri grandis, C. grands, Citri Reticulatae Pericarpium, Citri Reticulatae Pericarpium Viride, Aurantii Fructus, and Aurantii Fructus Immaturus from Citrus, and analysis differences in the fingerprints to provide scientific basis for profile-effect research and clinical reasonable use. HPLC was performed on a C18 column with methanol-water (with acetic acid), to establish HPLC fingerprints of the six kinds of medicinal herbs on the same chromatograph condition. The six frequently used Chinese materia medica were divided into naringin type and hesperidin type according to the method of phytochemotaxonomy. Based on the retention time of chromatograph peaks, C. grandis and C. grands had fifteen common peaks; Citri Reticulatae Pericarpium, Citri Reticulatae Pericarpium Viride, Aurantii Fructus and Aurantii Fructus Immaturus had ten common peaks. All herbs had five common peaks. Compared with mutual model, the holistic similarity of chromatograms of C. grandis and C. grands was in the range of 0.9285 - 0.9962. The degree of similarity was high. For Citri Reticulatae Pericarpium, Citri Reticulatae Pericarpium Viride and Aurantii Fructus Immaturus, it was in the range of 0.9221 - 0.9973 and high. But the similarity of Aurantii Fructus was only in 0.4547 - 0.7733 with the mutual model. The established fingerprints of flavonoids of the six common traditional Chinese medicines can be used to compare the differences intuitively. Meanwhile, the peak height and peak areas of characteristic peaks are different remarkably, but whether it is connected with the different function of regulating Qi flow of the six medical materials in clinical use, is still needed to be studied.

  3. Alshamel fi Sana'at Tebbi'at: A Comprehensive Book on the Materia Medica.

    Science.gov (United States)

    Mosaffa-Jahromi, Maryam; Kiani, Hossein

    2016-05-01

    Ala-al-din abu Al-Hassan Ali ibn Abi-Hazm al-Qarshi al-Dimashqi, known as Ibn al-Nafis (1210-1288 AD), was a Muslim Syrian physician primarily famous for being the first to describe the pulmonary circulation of the blood. The most voluminous of his books is Alshamel fi Sana'at tebbi'at, which is a comprehensive medical encyclopedia. It comprised 300 volumes of notes, from which only 80 volumes are published. His writings are cataloged in many libraries around the world. The aim of this review article, as a tribute to Ibn al-Nafis, was to introduce his valuable but neglected encyclopedia of Materia Medica. Ibn al-Nafis' traditional approach in his "Alshamel fi Sana'at tebbi'at" book is studied in the present article. Alshamel fi Sana'at tebbi'at covers three branches of knowledge. The first category is devoted to theoretical traditional medicine. The second is in four sections where much of it is not available yet. The third category is on Materia Medica covering the aspect of Unani medicine, from which only 28 volumes of the comprehensive book on the traditional medicine have been found so far. The latter, introduces mono-ingredient medications in alphabetical order. Each chapter, in several parts, is dedicated to the botanical characteristics and nature of each mono-ingredient medication. In addition, this book explains traditional pharmacokinetic of every single medication for each human body organs. Based on pharmaco-mechanistic perspective on Alshamel fi Sana'at tebbi'at, it could be considered as the main reference book on traditional medicine and pharmacy, worthy of revival.

  4. Studies of beneficial interactions between active medicaments and excipients in pharmaceutical formulations.

    Science.gov (United States)

    Kalinkova, G N

    1999-09-30

    A review of "up to date" research findings leading to new concepts of the pharmaceutical formulations and their interactions has been presented. The rational approaches to the excipients choice as well as to their interactions with medicaments have been shown as a basis for modern modelling of pharmaceutical formulations. The importance of complexation, hydrogen bonding, ion-dipole, dipole-dipole and van der Waals attractions as the tools which can modify the physicochemical, pharmacological or pharmacokinetical behaviour of the medicaments has been emphasised. In vivo studies (carried out in healthy human subjects-volunteers, in beagle dogs, in rats etc.) and in vitro studies (on excised human skin, hairless mouse skin etc.) as well as studies of chemical stability and bioavailability serve also as a proof of these interactions. Therefore, excipients are important components of pharmaceutical formulations and they can take an active part in the improvement of the characteristics of formulations (but they may also reduce the effectiveness of some preparations). In this context, the so called active and inactive ingredients in pharmaceutical formulations are inexact, old and "out-of date". Their further use is only conventional. In conclusion, among the various modern techniques applied the combination of infrared spectroscopy and X-ray diffraction has been estimated as the most successful in proving the interactions between drugs and excipients. Finally, pharmaceutical formulations and their interactions have constituted a diverse and rapidly expanding field of Pharmacy (Pharmaceutical Technology, Pharmaceutical Industry and Pharmaceutical Sciences) which covers a wide range of numerical topics within an unified framework.

  5. Effect of four different intracanal medicaments on the apical seal of the root canal system: a dye extraction study.

    Science.gov (United States)

    Tandan, Monika; Hegde, Mithra N; Hegde, Priyadarshini

    2014-01-01

    The aim was to determine the effect of four different intracanal medicaments on the apical seal of the root canal system in vitro. Fifty freshly extracted intact human permanent maxillary central incisors were collected, stored and disinfected. The root canals were prepared to a master apical size of number 50 using step back technique. Depending upon the intracanal medicament used, the teeth were divided randomly into five groups of 10 teeth each including one control group and four experimental groups. Group A: No intracanal medicament. Group B: Calcium hydroxide powder mixed with distilled water. Group C: Calcium hydroxide gutta percha points (calcium hydroxide points). Group D: 1% chlorhexidine gel (hexigel). Group E: Chlorhexidine gutta percha points (Roeko Activ Points). The medication was left in canals for 14 days. Following removal of the intracanal medicament, all the groups were obturated with lateral compaction technique. The apical leakage was then evaluated using dye extraction method with the help of a spectrophotometer. RESULTS were statistically analyzed using Kruskal-Wallis and Mann-Whitney U-test, which showed statistically significant difference among the five groups tested. It can be concluded from this study that the control group showed least amount of leakage, whereas the 1% chlorhexidine gel group showed maximum amount of leakage. Apical leakage was observed with all the experimental groups with little variations in between them. Under the parameters of this study, it can be concluded that use of intracanal medicaments during endodontic treatment has a definite impact on the apical seal of the root canal system.

  6. Choeur du CERN : Concert

    CERN Multimedia

    CERN Choir

    2017-01-01

    Une œuvre à découvrir! La grande Missa pro defunctis de François-Joseph Gossec (1734-1829) est le chef-d’œuvre tôt venu (à vingt-cinq ans) d’un compositeur qui vivra encore 70 ans après sa création. Elle a connu la gloire, puis s’est fait un peu oublier. Pas du tout le monde cependant : des musicologues ont montré ce que le Requiem de Mozart lui devait ; et il suffit de l’avoir entendue pour comprendre pourquoi Berlioz (qui avait vingt-six ans à la mort de Gossec) en a été impressionné : les nombreux cuivres et bois répartis dans des endroits plus ou moins cachés de la salle de concert pour exprimer les frayeurs du Jugement dernier annoncent son Requiem – et celui de Verdi. Mais « plus encore que par...

  7. Les risques du travail

    CERN Document Server

    Thébaud-Mony, Annie

    2015-01-01

    Depuis les années 1990, les conditions de travail se sont peu à peu imposées dans le débat social. Néanmoins, la situation reste critique. Les risques traditionnels n'ont pas disparu : les manutentions lourdes, l'exposition professionnelle aux cancérogènes, au bruit ou aux vibrations demeurent répandues... De plus, certaines " améliorations " n'ont fait que déplacer et dissimuler les problèmes, telle l'externalisation des risques grâce à la sous-traitance. Dans le même temps, les transformations du travail et des modalités de gestion de la main-d'œuvre ont fragilisé les collectifs et accru l'isolement des salariés, conduisant à une montée visible de la souffrance psychique. Face à ces évolutions, il est plus que jamais nécessaire que tous les acteurs concernés, en particulier les salariés eux-mêmes et leurs représentants, s'approprient les connaissances indispensables pour améliorer la protection de la santé sur les lieux du travail. Tel est le but de ce livre, qui renouvelle int�...

  8. Tissue Metabolism of Tritium-Labelled Thyroid Hormones and Thyronine; Sur le Metabolisme Cellulaire d'Hormones Thyroiediennes Marquees par le Tritium; 0422 043a 0430 043d 0435 0432 044b 0439 043c 0414 ; Metabolismo de las Hormonas Tiroideas y de la Tironina Marcadas con {sup 3}H en los Tejidos

    Energy Technology Data Exchange (ETDEWEB)

    Roche, J.; Nunez, J.; Jacquemin, Cl. [Laboratoire de Biochimie Generale et Comparee, College de France, Paris (France)

    1962-02-15

    Desiodation of thyroid hormones results in the formation of iodides and of thyronine (T{sub 0}), the description of which has been based on tissue sections or on a thyroxine desiodase preparation. We have provided direct evidence of this process: 3,5,3'-triiodothyronine and 3,3',5'-triiodothyronine, each tritiumlabelled at alpha-beta and at 3, result - inter alia, in the kidney - in the formation of T{sub 0}. The identification of T{sub 0} as a natural derivative of thyroid hormones justified the study of its tissue metabolism; T{sub 0} which was tritium-labelled at 3,5 was incubated in-vitro with sections of kidney and muscle. By liquid scintillation radiochromatogryphy and by radioautography we identified: (1) tyrosine, whose formation is evidence of the rupture of the diphenylether bridge of T{sub 0}; (2) 3'-hydroxythyronine and 3,4-dihydroxyphenylalanine, whose presence shows that 0-hydroxylation occurs in the catabolism of the cycles; (3) thyroacetic acid and p-hydroxyphenylacetic acid, whose appearance is in keeping with the general scheme of alpha-aminated acid degradation. (author) [French] La desio- dation des hormones thyroiediennes conduit a la formation d'iodures et de thyronine (T{sub 0}) dont la caracterisation a ete realisee a partir de coupes de tissus ou d'une preparation de thyroxine desiodase. Les auteurs apportent une preuve directe de ce processus: la 3, 5,3'-triiodothyronine et la 3,3', 5'-triiodothyronine marquees respectivement en {alpha} {beta} et en 3 par {sup 3}H conduisent, dans le rein, entre -autres, a la formation de T{sub 0}. L'identification de T{sub 0} comme-derive naturel des hormones thyroiediennes justifiait l'etude de son metabolisme tissulaire ; T0 marquee en 3,5 par {sup 3}H a ete incubee in vitro avec des coupes de rein -et de muscle. Les auteurs ont caracterise par radiochromatographie en scintillation liquide et autoradiographie : 1. La tyrosine dont la formation temoigne de la rupture du pont diphenylether de T{sub 0}. '2

  9. Jouer du piano

    Directory of Open Access Journals (Sweden)

    Fériel Kaddour

    2011-04-01

    Full Text Available La réflexion s’appuie dans un premier temps sur une opposition entre deux attitudes de pianistes  à l’égard du travail à l’instrument : Gould, qui revendique une séparation d’avec le clavier pour ne privilégier que la lecture; Arrau, dont la technique au contraire vise à « faire corps » avec son piano. L’étude de ces deux démarches d’interprètes conduit à une conclusion croisée : l’abstraction gouldienne n’est rien d’autre qu’un déplacement du jeu vers d’autres instruments (ceux qui servent à la prise de son et au montage de ses enregistrements ; le « faire-corps » hérité de la culture pianistique romantique est plus dialectique que fusionnel, et en cela implique une capacité de mise à distance. A partir de cette double conclusion, on tâche enfin de repenser la place du jeu à l’instrument dans la mise en œuvre d’une interprétation, en interrogeant le dialogue qui s’instaure entre la partition telle qu’elle s’écrit et le geste tel qu’il se joue.Our study leans on an opposition between two pianists' attitudes about their work with the instrument. Gould claims a necessary separation from the keyboard in order to prioritize reading. Arrau, on the contrary, relies on a technique which consists in “being one” with his piano. The analysis of these two interprets’ behaviours leads to a crossed conclusion: the gouldian abstraction is nothing else than a displacement of the playing towards another kind of instruments, the ones he uses in sound recording and cut up; Arrau’s “being one” is more dialectic than at first sight, and it therefore implies a real distancing from the piano. This constatation leads to rethink the place of the piano playing in the setting of an interpretation, and to highlight the real dialogue which develops itself between the score as it has been written and the gesture as it is played.

  10. [Investigation on pattern of quality control for Chinese materia medica based on famous-region drug and bioassay--the work reference].

    Science.gov (United States)

    Yan, Dan; Xiao, Xiaohe

    2011-05-01

    Selection and standardization of the work reference are the technical issues to be faced with in the bioassay of Chinese materia medica. Taking the bioassay of Coptis chinensis. as an example, the manufacture process of the famous-region drugs extraction was explained from the aspects of original identification, routine examination, component analysis and bioassay. The common technologies were extracted, and the selection and standardization procedures of the work reference for the bioassay of Chinese materia medica were drawn up, so as to provide technical support for constructing a new mode and method of the quality control of Chinese materia medica based on the famous-region drugs and bioassay.

  11. La grammaticalisation du monde.

    Directory of Open Access Journals (Sweden)

    Etienne Pingaud

    2010-01-01

    Full Text Available Ouvrage atypique par le fond comme par la forme, Le devoir et la grâce rend compte du minutieux travail d’élaboration théorique auquel s’attelle Cyril Lemieux depuis plusieurs années. Et le résultat final se veut pour le moins ambitieux : l’auteur propose un système total supposé dépasser d’un même élan le relativisme, le mentalisme, l’universalisme ethnocentrique, l’historicisme, le naturalisme et l’herméneutisme, tout en réconciliant les sciences sociales avec le ...

  12. Le sacre du printemps

    Directory of Open Access Journals (Sweden)

    Denise Pumain

    2002-03-01

    Full Text Available Cybergeo aura six ans en avril : dans la réalité du virtuel, dans l'univers récent et fluctuant de la publication en ligne, cela fait de nous, tout à la fois, des pionniers et des vétérans. De façon plus surprenante, il se trouve que nous sommes aussi uniques : parmi toutes les revues électroniques de sciences sociales, aucune ne combine comme Cybergeo ancienneté, publication exclusivement électronique, liberté d'accès au texte intégral, édition et gestion par des chercheurs, et comité de lec...

  13. Le Brahmane du Komintern

    Directory of Open Access Journals (Sweden)

    Elizabeth Burgos

    2008-01-01

    Full Text Available Le Brahmane du Komintern, largometraje documental del realizador francés Vladimir León, constituye un ejercicio ejemplar de investigación histórica y  de lograda factura de realización. Y, pese a no haber contado con la ayuda de ninguno organismo público, se trata de un ambicioso proyecto que cubre una amplia extensión geográfica que abarca: Estados Unidos, México, Moscú, Berlín, y la India. Gira en torno a una figura que tuvo en su tiempo su hora de gloria. Un bengalí, hijo de braman, la c...

  14. (Sorghum bicolor (L.) Moench) du Nord du Burkina Faso

    African Journals Online (AJOL)

    SARAH

    29 déc. 2014 ... sorghos à grains sucrés ont un cycle court et arrivent donc à maturité avant les autres sorghos et le mil d'où leur exploitation comme aliment de soudure par les paysans. L'organisation de la diversité morphologique des accessions de sorghos à grains sucrés du Nord du. Burkina autour principalement des ...

  15. OPERATION DU FOISONNEMENT

    Directory of Open Access Journals (Sweden)

    Gholamreza Djelveh

    2010-04-01

    Full Text Available Mousses alimentaires sont un sous-ensemble des aliments connus sous le nom de produits fouettés ou des produits aérés. Ils sont des produits formulés avec des qualités telles que la légèreté et la souplesse et sont principalement consommés à l'apéritif ou au dessert. Les produits en mousse obtenue par dispersion d'un gaz dans une matrice alimentaire (la phase continue ont connu un développement croissant au cours des années 80 et 90. Le processus d'aération liés à leurs activités de production est appelée l'expansion ou à fouetter. Le document présente les principaux-paramètres du procédé du point permanent de la formulation, la mise en œuvre processus dans les installations pilotes et à l'échelle industrielle, la caractérisation des produits finis, la base énergétique de l'échelle de processus en place, et le lien entre la formulation, émulsion préparation de l'expansion. Cette vue d'ensemble de l'opération d'expansion continue, nous a permis de mettre en évidence le fait qu'il ya des opérations de l'unité encore mal décrite par le génie des procédés et pour lesquels les méthodes et outils pour l'extrapolation et la prédiction sont encore à leurs balbutiements.

  16. Alimentation du nouveau-ne et du nourrisson dans la region ...

    African Journals Online (AJOL)

    Alimentation du nouveau-ne et du nourrisson dans la region centrale du togo : pratiques familiales et communautaires avant la mise en oeuvre de la strategie « prise en charge integree des maladies de l'enfant »

  17. Chinese vegetative materia medica in a venereological treatise by Jean Astruc from 1740.

    Science.gov (United States)

    Drobnik, Jacek

    2016-07-01

    Historical medical sources can be still queried for forgotten cures and remedies. Traditional Chinese medicine has dealt with lues venerea (syphilis) since the Five Dynasties period (10th century). Chinese indigenous materia medica and remedies recorded, studied or imported by the Europeans can reveal known or quite unknown medicinal plants. The studied Jean Astruc's work is a published ethnopharmacological survey carried out in Beijing in the 1730s and it deserves a modern interpretation. This is the first proposal to identify historical Chinese medicinal plants listed in a scarcely known medical treatise De Morbis venereis… ('On venereal diseases…') by Jean Astruc from 1740. I searched for the current uses and position of the taxonomically identified herbal stock in both traditional Chinese and official medical knowledge, with special attention to syphilis. Chinese names of drugs and their botanical identities (originally expressed by means of pre-Linnaean polynomials, and now interpreted as accepted binomials) were independently cross-checked with younger till most recent taxonomical and ethnopharmacological sources. Plants and drugs identified this way were queried for their modern applications in traditional Chinese and official medicine with special attention to sexually transmitted diseases (STD) and other uses which are similar to the 18th-century understanding of venereology. For 24 items of medicinal stock, 34 medicinal plants have been identified or suspected: Acacia catechu, Achyranthes bidentata, Akebia quinata, Angelica dahurica, A. sinensis, Aquilaria sinensis, Aralia cordata, Aristolochia fangchi, Chaenomeles sinensis, Ch. speciosa, Clematis vitalba, Coix lacryma-jobi, Commiphora myrrha, Cydonia oblonga, Daemonorops draco, D. jenkinsiana, Dictamnus dasycarpus, Dryobalanops sumatrensis, Forsythia suspensa, Glycyrrhiza uralensis, Lonicera confusa, L. hypoglauca, L. japonica, Ligusticum striatum (=L. chuanxiong), Piper kadsura, Pterocarpus

  18. Biochemia Medica has started using the CrossCheck plagiarism detection software powered by iThenticate

    Science.gov (United States)

    Šupak-Smolčić, Vesna; Šimundić, Ana-Maria

    2013-01-01

    In February 2013, Biochemia Medica has joined CrossRef, which enabled us to implement CrossCheck plagiarism detection service. Therefore, all manuscript submitted to Biochemia Medica are now first assigned to Research integrity editor (RIE), before sending the manuscript for peer-review. RIE submits the text to CrossCheck analysis and is responsible for reviewing the results of the text similarity analysis. Based on the CrossCheck analysis results, RIE subsequently provides a recommendation to the Editor-in-chief (EIC) on whether the manuscript should be forwarded to peer-review, corrected for suspected parts prior to peer-review or immediately rejected. Final decision on the manuscript is, however, with the EIC. We hope that our new policy and manuscript processing algorithm will help us to further increase the overall quality of our Journal. PMID:23894858

  19. [Textual research on Costus root (Aucklandia lappa Decne) in the Sheng nong ben cao jing (Shennong's Classic of Materia Medica)].

    Science.gov (United States)

    Li, Guangyan; Wang, Dequn; Fang, Shiying; Xu, Maohong

    2014-05-01

    Aucklandia lappa Decne was first recorded in the Sheng nong ben cao jing (Shennong's Classic of Materia Medica). Through the textual research of herbal literature, it was found that the costus root in the Sheng nong ben cao jing perhaps was not the plant of Aucklandia lappa Decne of Compositae, but the eaglewood or Lignum Aquilasria Resinatum based on the comprehensive judgment of shape, taste, nature, and function etc. In the Sheng nong ben cao jing, it only includes costus root without the title of eaglewood, and Tao Hongjing recorded both herbs together in his Ming yi bie lu (Supplementary Records of Celebrated Physicians), which became a foreshadow of misunderstanding of the later generations. Beginning from the Tang ben cao (Materia Medica of the Tang Dynasty), the costus root was considered as the plant of Auckiandia lappa Decne from the Compostae with its profound influence until now.

  20. Histological Evaluation of Allium sativum Oil as a New Medicament for Pulp Treatment of Permanent Teeth.

    Science.gov (United States)

    Mohammad, Shukry Gamal; Raheel, Syed Ahmed; Baroudi, Kusai

    2015-02-01

    The objective of this study was to evaluate the histo pathology effects of two medicaments Allium sativum oil and formocresol on the remaining pulp tissue of the permanent teething children. A total of 18 premolars were included in this study. Two sound premolars were extracted and subjected to histological examination to show the normal pulp tissue. Pulpo tomy procedure was performed in the rest of the remaining 16 premolars; half of them using Allium sativum oil and the rest of the tested premolars were medicated using formocresol and all were sealed with suitable restoration. Then, premolars extracted at variable intervals (48 hours, 2 weeks, 1 month, 2 months), stained using hemotoxylin and eosin etain (H&E) and prepared for histopathology examination. Histological evaluation seemed far more promising for Allium sativum oil than formocresol. Histological evaluation revealed that teeth treated with Allium sativa oil showed infammatory changes that had been resolved in the end of the study. On the contrary, the severe chronic infammation of pulp tissue accompanied with formocresol eventually produced pulp necrosis with or without fibrosis. In addition, pulp calcification was evidenced in certain cases. Allium sativum oil is a biocompatible material that is compatible with vital human pulp tissue. It offers a good healing potential, leaving the remaining pulp tissue healthy and functioning.

  1. A acetamida de pirrolidona como medicação auxiliar no tratamento da paralisia cerebral

    Directory of Open Access Journals (Sweden)

    Francisca Salete Pinheiro Chagas Ribeiro

    1976-06-01

    Full Text Available Vinte crianças, com diagnóstico de paralisia cerebral (PC e sob tratamento clássico, fisioterápico e pedagógico, receberam piracetam (acetamida de pirrolidona como medicação auxiliar. O objetivo foi melhorar os problemas de espasticidade, apredizagem, neurolabilidade, visando a um rendimento melhor do tratamento global da PC. O grupo medicado foi comparado com um grupo controle de 20 crianças que só eram objeto do tratamento habitual. A comparação mostrou resultados favoráveis no grupo medicado. A droga foi administrada na dose de 80 mg/kg/dia durante 10 semanas. Os critérios de avaliação dos resultados foram psicológicos, clínico, fisioterápico e pedagógico. A droga foi administrada em nova forma de apresentação: solução, para uso oral, a 6%.

  2. Green synthesis of copper nanoparticles by Citrus medica Linn. (Idilimbu) juice and its antimicrobial activity.

    Science.gov (United States)

    Shende, Sudhir; Ingle, Avinash P; Gade, Aniket; Rai, Mahendra

    2015-06-01

    We report an eco-friendly method for the synthesis of copper nanoparticles (CuNPs) using Citron juice (Citrus medica Linn.), which is nontoxic and cheap. The biogenic copper nanoparticles were characterized by UV-Vis spectrophotometer showing a typical resonance (SPR) at about 631 nm which is specific for CuNPs. Nanoparticles tracking analysis by NanoSight-LM20 showed the particles in the range of 10-60 nm with the concentration of 2.18 × 10(8) particles per ml. X-ray diffraction revealed the FCC nature of nanoparticles with an average size of 20 nm. The antimicrobial activity of CuNPs was determined by Kirby-Bauer disk diffusion method against some selected species of bacteria and plant pathogenic fungi. It was reported that the synthesized CuNPs demonstrated a significant inhibitory activity against Escherichia coli followed by Klebsiella pneumoniae, Pseudomonas aeruginosa, Propionibacterium acnes and Salmonella typhi. Among the plant pathogenic fungi tested, Fusarium culmorum was found to be most sensitive followed by F. oxysporum and F. graminearum. The novelty of this work is that for the first time citron juice was used for the synthesis of CuNPs.

  3. [Rapid assessment of critical quality attributes of Chinese materia medica (II): strategy of NIR assignment].

    Science.gov (United States)

    Pei, Yan-Ling; Wu, Zhi-Sheng; Shi, Xin-Yuan; Zhou, Lu-Wei; Qiao, Yan-Jiang

    2014-09-01

    The present paper firstly reviewed the research progress and main methods of NIR spectral assignment coupled with our research results. Principal component analysis was focused on characteristic signal extraction to reflect spectral differences. Partial least squares method was concerned with variable selection to discover characteristic absorption band. Two-dimensional correlation spectroscopy was mainly adopted for spectral assignment. Autocorrelation peaks were obtained from spectral changes, which were disturbed by external factors, such as concentration, temperature and pressure. Density functional theory was used to calculate energy from substance structure to establish the relationship between molecular energy and spectra change. Based on the above reviewed method, taking a NIR spectral assignment of chlorogenic acid as example, a reliable spectral assignment for critical quality attributes of Chinese materia medica (CMM) was established using deuterium technology and spectral variable selection. The result demonstrated the assignment consistency according to spectral features of different concentrations of chlorogenic acid and variable selection region of online NIR model in extract process. Although spectral assignment was initial using an active pharmaceutical ingredient, it is meaningful to look forward to the futurity of the complex components in CMM. Therefore, it provided methodology for NIR spectral assignment of critical quality attributes in CMM.

  4. Effects of Chinese Materia Medica-Fubao Danggui Jiao on experimental endometriosis.

    Science.gov (United States)

    Sun, Xing; Chen, Lijue; Zeng, Fanbo

    2011-01-01

    The objective of this paper was to investigate the effects of a Chinese Materia Medica variant -Fubao Danggui Jiao (FDJ)-on experimental endometriosis. An endometriosis model was created by virtue of auto-transplantation of endometrial tissue onto rats' abdominal walls. The implants were allowed to grow for 30 days until the successful completion of the model. After that, forty endometriotic rats were randomly divided into four study groups and given different treatments: (1) negative control group (water, 2ml/kg, per os); (2) FDJ-A group (FDJ, 2ml/kg, per os); (3) FDJ-B group (FDJ, 4ml/kg, per os); (4) Danazol group (70mg/kg, per os). After 30 days with treatments, the volumes of endometriotic implants in each rat were measured. The implants and normal uterine horns were removed for routine histological examination. FDJ caused significant decreases in volumes of the surviving endometriotic implants, with two different doses having statistically equivalent effects. Upon histological examination, FDJ was observed to cause regression of epithelium and stroma of endometriotic implants. FDJ had revealed promising therapeutic effects on endometriosis.

  5. [Design and implementation of Chinese materia medica resources survey results display system].

    Science.gov (United States)

    Wang, Hui; Zhang, Xiao-Bo; Ge, Xiao-Guang; Jin, Yan; Wang, Ling; Zhao, Yan-Ping; Jing, Zhi-Xian; Guo, Lan-Ping; Huang, Lu-Qi

    2017-11-01

    From the beginning of the fourth national census of traditional Chinese medicine resources in 2011, a large amount of data have been collected and compiled, including wild medicinal plant resource data, cultivation of medicinal plant information, traditional knowledge, and specimen information. The traditional paper-based recording method is inconvenient for query and application. The B/S architecture, JavaWeb framework and SOA are used to design and develop the fourth national census results display platform. Through the data integration and sorting, the users are to provide with integrated data services and data query display solutions. The platform realizes the fine data classification, and has the simple data retrieval and the university statistical analysis function. The platform uses Echarts components, Geo Server, Open Layers and other technologies to provide a variety of data display forms such as charts, maps and other visualization forms, intuitive reflects the number, distribution and type of Chinese material medica resources. It meets the data mapping requirements of different levels of users, and provides support for management decision-making. Copyright© by the Chinese Pharmaceutical Association.

  6. Targeting tumor-associated macrophages by anti-tumor Chinese materia medica.

    Science.gov (United States)

    Pu, Wei-Ling; Sun, Li-Kang; Gao, Xiu-Mei; Rüegg, Curzio; Cuendet, Muriel; Hottiger, Micheal O; Zhou, Kun; Miao, Lin; Zhang, Yun-Sha; Gebauer, Margaret

    2017-10-01

    Tumor-associated macrophages (TAMs) play a key role in all stages of tumorigenesis and tumor progression. TAMs secrete different kinds of cytokines, chemokines, and enzymes to affect the progression, metastasis, and resistance to therapy depending on their state of reprogramming. Therapeutic benefit in targeting TAMs suggests that macrophages are attractive targets for cancer treatment. Chinese materia medica (CMM) is an important approach for treating cancer in China and in the Asian region. According to the theory of Chinese medicine (CM) and its practice, some prescriptions of CM regulate the body's internal environment possibly including the remodeling the tumor microenvironment (TME). Here we briefly summarize the pivotal effects of TAMs in shaping the TME and promoting tumorigenesis, invasion, metastasis and immunosuppression. Furthermore, we illustrate the effects and mechanisms of CMM targeting TAMs in antitumor therapy. Finally, we reveal the CMM's dual-regulatory and multi-targeting functions on regulating TAMs, and hopefully, provide the theoretical basis for CMM clinical practice related to cancer therapy.

  7. Effect of four different intracanal medicaments on the apical seal of the root canal system: A dye extraction study

    Directory of Open Access Journals (Sweden)

    Monika Tandan

    2014-01-01

    Conclusion: It can be concluded from this study that the control group showed least amount of leakage, whereas the 1% chlorhexidine gel group showed maximum amount of leakage. Apical leakage was observed with all the experimental groups with little variations in between them. Under the parameters of this study, it can be concluded that use of intracanal medicaments during endodontic treatment has a definite impact on the apical seal of the root canal system.

  8. [Suitable investigation method of exploration and suggestions for investigating Chinese materia medica resources from wetland and artificial water of Hongze Lake region].

    Science.gov (United States)

    Liu, Rui; Yan, Hui; Duan, Jin-Ao; Liu, Xing-Jian; Ren, Quan-Jin; Li, Hui-Wei; Bao, Bei-Hua; Zhang, Zhao-Hui

    2016-08-01

    According to the technology requirements of the fourth national survey of Chinese Materia Medica resources (pilot), suitable investigation method of exploration and suggestions for investigating Chinese Materia Medica resources was proposed based on the type of wetland and artificial water of Hongze Lake region. Environment of Hongze Lake and overview of wetland, present situation of ecology and vegetation and vegetation distribution were analyzed. Establishment of survey plan, selection of sample area and sample square and confirmation of representative water area survey plan were all suggested. The present study provide references for improving Chinese materia medica resources survey around Hongze Lake, and improving the technical specifications. It also provide references for investigating Chinese Materia Medica resources survey on similar ecological environment under the condition of artificial intervention. Copyright© by the Chinese Pharmaceutical Association.

  9. Le plurilinguisme du perroquet

    Directory of Open Access Journals (Sweden)

    Manuel Mühlbacher

    2012-05-01

    Full Text Available La figure du perroquet occupe une position ambiguë face à la question de la traduction. Il est capable d’imiter des paroles en toutes les langues, mais il n’est capable d’en comprendre aucune — il ne peut que répéter des sons, c’est-à-dire des signifiants. Le traducteur semble faire le contraire quand il passe d’une langue à une autre en tâchant de transmettre une signification semblable par d’autres signes. L’article vise à discuter le rôle du traducteur et sa relation, éventuellement équivoque, au perroquet, en analysant la traduction allemande de Trois Contes par André Stoll et Cora van Kleffens. Un décalage au niveau sémantique peut éclairer l’interprétation du texte, par exemple en explicitant des allusions sous-jacentes, tandis que le transfert de la syntaxe française en allemand pose souvent des problèmes considérables. Comment le traducteur peut-il reproduire des structures syntaxiques qui n’existent pas en allemand, mais qui ne cessent de revenir dans le texte français ? Que faire si le texte se met à jouer au perroquet et finit par se singer lui-même ? André Stoll et Cora van Kleffens ont su trouver des stratégies pour affronter ces difficultés.The figure of the parrot holds an ambiguous position towards the question of translation. It is able to imitate all languages, but it will never understand any of them – its only skill is to mimic sounds, i.e. mere signifiers. On the contrary, the translator seems to be the antithesis of the parrot when he moves from one language to another. He endeavours to convey a similar meaning, but by different signs. The article aims at discussing the role of the translator and his or her eventually equivocal relation to the parrot by means of analysing the German translation of Trois Contes by André Stoll and Cora van Kleffens. Whereas a semantic divergence can result in a different tendency on the level of interpretation, as in the case of an underlying

  10. KAEMPFEROL, A FLAVONOID COMPOUND FROM GYNURA MEDICA INDUCED APOPTOSIS AND GROWTH INHIBITION IN MCF-7 BREAST CANCER CELL.

    Science.gov (United States)

    Yi, Xiaofang; Zuo, Jiangcheng; Tan, Chao; Xian, Sheng; Luo, Chunhua; Chen, Sai; Yu, Liangfang; Luo, Yucheng

    2016-01-01

    Kaempferol, a natural flavonoid, has been shown to induce cancer cell apoptosis and cell growth inhibition in several tumors. Previously we have conducted a full investigation on the chemical constituents of Gynura medica , kaempferol and its glycosides are the major constituents of G. medica . Here we investigated the growth inhibition and apoptosis induction effect of kaempferol extracted from G. medica . The inhibition effects of kaempferol were evaluated by MTS assay and soft agar colony formation assay. Fluorescence staining and western blotting were be used to study the apoptosis. The structure was identified by 1 H- NMR), 13 C-NMR and ESI-MS analyses. Our results showed that kaempferol's inhibition of MCF-7 breast cancer cell growth may through inducing apoptosis and downregulation of Bcl2 expression. Kaempferol is a promising cancer preventive and therapeutic agent for breast cancer. List of non-standard abbreviations: MTS: 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, HPLC: High-performance liquid chromatography, NMR: Nuclear Magnetic Resonance, ESI-MS Electrospray Ionization Mass Spectral, PARP: Poly ADP-ribose polymerase.

  11. [Report quality evaluation of systematic review or Meta-analysis published in China Journal of Chinese Materia Medica].

    Science.gov (United States)

    Zhang, Yan; Yu, Dan-Dan; Cui, De-Hua; Liao, Xing; Guo, Hua

    2018-03-01

    To evaluate the report quality of intervention-related systematic reviews or Meta-analysis published in China Journal of Chinese Materia Medica, we searched CNKI and China Journal of Chinese Materia Medica webpages to collect intervention-related systematic reviews or Meta-analysis since the first issue of the magazine. A total of 40 systematic reviews or Meta-analysis reports were included, including one network Meta-analysis. According to the PRISMA statement published in 2009, the report quality of the systematic reviews or Meta-analysis was evaluated. According to the results, 3 had the low quality, 30 had the medium quality, and 7 had the high quality. The average score for all of items was 30 points (21-30.5 points for the medium quality). The 17 high-quality (31-40 points) report items were title, rationale, objectives, information sources, study selection, data collection process, data items, risk of bias in individual studies, summary measures, risk of bias across studies, study selection, study characteristics, risk of bias within studies, results of individual studies, synthesis of results, risk of bias across studies and funding; the 4 medium-quality (21-30.5 points) reporting items were eligibility criteria, search, limitations and conclusions; and the 6 low-quality (Materia Medica is medium, and it is necessary to improve the quality standard of the report. Copyright© by the Chinese Pharmaceutical Association.

  12. Etat Du Magnesium Dans Quelques Sols Sales Du Sud Et Du ...

    African Journals Online (AJOL)

    étude a été réalisée sur 86 échantillons de sols provenant du Centre et du Sud de l´Irak. L\\'expérimentation a consisté, d´une part, à calculer les différents sels dominants dans les sols salés par la méthode de combinaison hypothétique et, ...

  13. Caractérisation des sables et morphologie du fond du lac du ...

    African Journals Online (AJOL)

    Une analyse sédimentologique et minéralogique réalisée sur un cycle hydrologique entre octobre 2004 et août 2005 a permis d\\'évaluer les charges solides en suspension et de caractériser les sédiments du lac du barrage de Taabo. La concentration moyenne en matières en suspension (12 mg.L-1) et la turbidité ...

  14. Caractérisation des sables et morphologie du fond du lac du ...

    African Journals Online (AJOL)

    Administrateur

    Une analyse sédimentologique et minéralogique réalisée sur un cycle hydrologique entre octobre 2004 et août 2005 a permis d'évaluer les charges solides en suspension et de caractériser les sédiments du lac du barrage de Taabo. La concentration moyenne en matières en suspension (12 mg.L-1) et la turbidité ...

  15. Biblioteca Medica in Trient und die Initiative „Es gibt ein Kind im Krankenhaus … Schenk ihm ein Buch!“

    Directory of Open Access Journals (Sweden)

    Trevisan, Sergio

    2016-12-01

    Full Text Available In the autumn of 2011 the Biblioteca Medica of the hospital in Trento (Italy received four thousand children’s and youth books. They were donated during a philanthropic action by customers of a bookstore chain. Together with volunteers of the ABIO Foundation, the Biblioteca Medica has partly donated these media to the children in the hospital and, with the rest of the books, organized some bookshelf at the pediatric wards.

  16. [Applications and approved projectsof general program, young scientist fund and fund for less developedregion of national natural science funds in discipline of Chinese materia medica, NSFC in 2012].

    Science.gov (United States)

    Huang, Ming-Qing; Han, Li-Wei; Wu, Xiu-Hong; Bi, Ming-Gang; Shang, Hong-Cai; Liu, Yun-Fang; He, Wei-Ming; Li, Dan-Dan; Dong, Yan; Wang, Chang-En

    2013-01-01

    The applications accepted and approved by general program, young scientist fund and fund for less developed region of national natural science funds in the discipline of Chinese materia medica, NSFC in 2012 have been introduced. The research contents of the funded projects in the popular research areas have been summarized and the problems in the applications have been analyzed to give a reference to the scientists in the field of Chinese materia medica.

  17. Le bal du loup

    CERN Multimedia

    Happy Children's Home

    2013-01-01

    The Bord'eau amateur theatre group will graciously perform a play of their creation Le bal du loup Saturday 19 October 2013 at 20:00 Sunday 20 October at 17:00 in the Théâtre des Grottes Rue Louis Favre 43, 1201 Genève Children from age 12 upwards. Summary: The new-elected mayoress of a small village would like to clean up the town by prohibiting alcohol and getting rid of its prostitutes. Then along comes « Massimo Lupo » the pimp... The performances will be given to support the Happy Children's Home charity, which runs a foster-home in Pokhara for Nepali children:  http://www.happychildrenshome.org/ Admission : minimum charge of 10 CHF per person requested, to cover the cost of technical assistance and theatre rental. Any profit will be used solely for the foster-home. At the end of each performance members of the HCH charity will be happy to answer any questions you may have. The theatre has 86 seats, thank you for reserv...

  18. Phenotypic and genetic diversity in Sinorhizobium meliloti and S. medicae from drought and salt affected regions of Morocco

    Directory of Open Access Journals (Sweden)

    Udupa Sripada M

    2010-01-01

    Full Text Available Abstract Background Sinorhizobium meliloti and S. medicae are symbiotic nitrogen fixing bacteria in root nodules of forage legume alfalfa (Medicago sativa L.. In Morocco, alfalfa is usually grown in marginal soils of arid and semi-arid regions frequently affected by drought, extremes of temperature and soil pH, soil salinity and heavy metals, which affect biological nitrogen fixing ability of rhizobia and productivity of the host. This study examines phenotypic diversity for tolerance to the above stresses and genotypic diversity at Repetitive Extragenic Pallindromic DNA regions of Sinorhizobium nodulating alfalfa, sampled from marginal soils of arid and semi-arid regions of Morocco. Results RsaI digestion of PCR amplified 16S rDNA of the 157 sampled isolates, assigned 136 isolates as S. meliloti and the rest as S. medicae. Further phenotyping of these alfalfa rhizobia for tolerance to the environmental stresses revealed a large degree of variation: 55.41%, 82.16%, 57.96% and 3.18% of the total isolates were tolerant to NaCl (>513 mM, water stress (-1.5 MPa, high temperature (40°C and low pH (3.5, respectively. Sixty-seven isolates of S. meliloti and thirteen isolates of S. medicae that were tolerant to salinity were also tolerant to water stress. Most of the isolates of the two species showed tolerance to heavy metals (Cd, Mn and Zn and antibiotics (chloramphenicol, spectinomycin, streptomycin and tetracycline. The phenotypic clusters observed by the cluster analysis clearly showed adaptations of the S. meliloti and S. medicae strains to the multiple stresses. Genotyping with rep-PCR revealed higher genetic diversity within these phenotypic clusters and classified all the 157 isolates into 148 genotypes. No relationship between genotypic profiles and the phenotypes was observed. The Analysis of Molecular Variance revealed that largest proportion of significant (P Conclusion High degree of phenotypic and genotypic diversity is present in S

  19. Effets de la microdose sur la production du niébé, du mil et du ...

    African Journals Online (AJOL)

    Effets de la microdose sur la production du niébé, du mil et du sorgho en fonction la toposéquence. Fatimata Saba, Sibiri Jean Baptiste Taonda, Idriss Serme, Alimata A. Bandaogo, Augustin P. Sourwema, Adama Kabre ...

  20. Dynamique des populations du foreur des tiges du cacaoyer ...

    African Journals Online (AJOL)

    SARAH

    30 nov. 2014 ... déprédateur dans la région du Haut-Sassandra, la deuxième plus grande région de production de cacao en. Côte d'ivoire. Méthodologie et résultats : L'étude a été réalisée de 2009 à 2013 dans les plantations villageoises de la région du Haut-Sassandra en Côte d'Ivoire. Les variations des taux d'attaques ...

  1. Dynamique des populations du foreur des tiges du cacaoyer ...

    African Journals Online (AJOL)

    Objectif : Le foreur de tiges du cacaoyer, Eulophonotus myrmeleon Felder cause aujourd'hui d'énormes dégâts dans les cacaoyères ivoiriennes. La présente étude vise à déterminer les périodes de fortes attaques de ce déprédateur dans la région du Haut-Sassandra, la deuxième plus grande région de production de ...

  2. The "schola medica salernitana": the forerunner of the modern university medical schools.

    Science.gov (United States)

    de Divitiis, Enrico; Cappabianca, Paolo; de Divitiis, Oreste

    2004-10-01

    The schola medica salernitana is considered the oldest medical school of modern civilization. Salerno's long medical tradition began during the Greco-Roman period in a Greek colony named Elea, where Parmenides decided to found a medical school. The fame of the school became more and more important during the 10th century, and it was best known in the 11th century. In the middle of 12th century, the school was at its apogee, and Salerno provided a notable contribution to the formulation of a medical curriculum for medieval universities. The most famous work of the Salernitan School was the Regimen Sanitatis Saleritanum, a Latin poem of rational, dietetic, and hygienic precepts, many of them still valid today. The school also produced a physician's reference book, with advice on how to treat a patient, a sort of code of conduct to help the physician to respect the patient and his or her relatives. The first science-based surgery appeared on the scene of the discredited medieval practice in Salerno, thanks to Roger of Salerno and his fellows. He wrote a book on surgery, called Rogerina or Post Mundi Fabricam, in which surgery from head to toe is described, with surprising originality. The important contribution to the School of Salerno made by women as female practitioners is outlined, and among them, Trotula de Ruggiero was the most renowned. The period when the School of Salerno, universally recognized as the forerunner of the modern universities, became a government academy was when Frederick II reigned over the Kingdom of the Two Sicilies, as Emperor of the Holy Roman Empire.

  3. [Understanding and development strategy of health food containing Chinese materia medica].

    Science.gov (United States)

    Wang, Lin-Yuan; Zhang, Jian-Jun; Wang, Chun; Wang, Jing-Xia; Zhu, Ying-Li; Wang, Jia; Gao, Xue-Min

    2016-11-01

    Health food containing Chinese materia medica (CMM) conforms to the development demands of the age of big health and the theory of preventive treatment. In the view of health care and improvement of resisting diseases, it plays an important role in the market. It is very necessary to have further study and discussion on health food containing CMM. First of all, by comparing, analyzing and summarizing, the health food containing CMM could be defined as the health food which is qualified in security and functionality evaluation, with the traditional Chinese medicines(TCM) within TCM standards as the main raw materials, and the formulation-composition is based on the theory of TCM. It is characterized by higher safety than medicines, stronger biological activities than common food, multiple forms, abundant raw materials and integrated supervision and management. Secondly, we discussed the research and development (R&D) strategies and rules of health food containing CMM, pointing out that the core tasks of R&D include the investigation of formula, technology and the standards of quality. The fundamental principles of declaration and production include scientificity, rationality, reality and uniformity. Three key requirements (security, functionality and controllability) in the review as well as the process management of R&D and the key-points of risks control were summarized in this paper. Finally, the dynamic trends of policies and regulations related to health food containing CMM were analyzed in the view of registration, recording, raw materials and functions, and then related suggestions were proposed. Therefore, this article will be helpful in overall understanding the health food containing CMM and play a guiding role for its research and development. Copyright© by the Chinese Pharmaceutical Association.

  4. What has been overlooked on study of Chinese materia medica in the West?

    Science.gov (United States)

    Liu, Willow J H

    2015-07-01

    Chinese materia medica (CMM), including Chinese herbal, animal, and mineral medicine, has been widely researched in the past century for their biological and pharmacological activities. However, their mechanism and clinical efficacy studies did not always give expected results. For example, the most commonly used Chinese herb for menstrual disorders, Radix Angelicae sinensis, showed neither estrogenic nor progesteronic activity in laboratory and clinical studies. Its efficacy should not be denied simply based on such results, because it is mostly used together with other herbs in formulae. Moreover, its regulation on menstruation may take effect through other mechanisms, such as regulation of blood circulation. The key difference of Chinese medicine (CM) from conventional medicine is its unique holistic view on human body and diseases. CMM is mostly applied in clinic in the form of formulae. Study on individual CMM, simply using methods for development of conventional drugs, is unable to thoroughly reveal the power of CMM formulae. The reason may partly result from improper design due to the lack understanding about application principle of CMMs in CM, and/or to current lack of knowledge about the causes of some symptoms and diseases. This paper will introduce the importance of qi and blood in CM etiology and pathology, Zheng differentiation, formulation of CMMs, and explain why one formula can treat different diseases and one disease can be treated with different formulae. Examples in the paper will demonstrate that proper studies on Zheng and its corresponding clinically proven formulae could help scientists find new direction to explain and treat symptoms and diseases that so far modern medicine has been unable to, provided that the designer properly understands CM theories, etiology and pathology of CM, as well as modern medicine. Strategy suggestions about research methods for CMM and its formulae will be given at the end.

  5. Gestion durable du paysage

    Directory of Open Access Journals (Sweden)

    Jean-David Gerber

    2009-03-01

    Full Text Available Le paysage est de plus en plus perçu comme une ressource. À ce titre, il est nécessaire de trouver des instruments juridiques, politiques ou économiques susceptibles de gérer cette « ressource-paysage » sur le long terme. Le gouvernement suisse a introduit récemment l’instrument des parcs naturels régionaux, organisés selon le modèle français, dans sa législation de protection de la nature et du paysage. Une mise en regard des nouveaux parcs avec des structures de gestion beaucoup plus anciennes, les bourgeoisies et les corporations, permet de mettre en évidence les forces et les faiblesses de chacun de ces instruments dans leur contribution à résoudre les rivalités d’usage entre acteurs utilisant ou influençant la ressource paysage. Cette comparaison permet de formuler des recommandations pratiques concernant la gestion de cette ressource.The landscape is increasingly perceived as a resource. For this reason, it is necessary to find legal, political and economic instruments that will succeed in managing this “resource landscape” in the long term. The Swiss government recently introduced the instrument of regional nature parks into the legislation governing nature and landscape preservation; the proposed parks are organized on the basis of the French model. The examination of the new parks from the perspective of much older management structures, i.e. the civic municipalities (bourgeoisies and corporations, makes it possible to demonstrate the strengths and weaknesses of each of these instruments in their contribution to the resolution of use rivalries between actors who use or influence the resource landscape. This comparison also enables the formulation of practical recommendations regarding the management of this resource.

  6. Le Developmental Entrepreneurship Program du Massachusetts ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Faire en sorte que les étudiants venant des pays en développement pour étudier au MIT retournent ensuite dans leurs pays respectifs afin d'y concrétiser leurs idées est un souci majeur du MIT, des bailleurs de fonds et du milieu du développement. Ce projet palliera à ce souci en soutenant la formation des fellows du ...

  7. Les dispositifs du Net art

    OpenAIRE

    Fourmentraux, Jean-Paul

    2010-01-01

    La pratique du Net art radicalise la question du potentiel communicationnel d’un média —Internet— qui constitue tout à la fois le support technique, l’outil créatif et le dispositif social de l’œuvre. Les technologies de l’information et de la communication (TIC) placent en effet l’œuvre d’art au cœur d’une négociation socialement distribuée entre l’artiste et le public. L’article est focalisé sur cette construction collective du Net art et sur ses mises en scènes. Il montre le travail artist...

  8. L'administration du travail et la production du droit du travail (1906-1960). : Note de synthèse du rapport de recherche

    OpenAIRE

    Le Crom , Jean-Pierre

    2007-01-01

    Synthèse d'un rapport de recherche dont l'objectif est d'appréhender le rôle de l'administration centrale du travail dans la production du droit du travail. Deux dimensions sont explorées : le profil des rédacteurs et l'organisation des structures.

  9. Réflexion sur l’origine du processus de segmentation du marche du travail

    Directory of Open Access Journals (Sweden)

    Attia Nicole

    2006-01-01

    Full Text Available (francuski Ce travail propose une réflexion sur l'origine du processus de segmentation du marché du travail par rapport à l'entreprise. Se situe-t-elle au sein même de l'entreprise ou en amont, c'est à dire entre les entreprises? Cela revient à se demander si on peut avoir une approche microéconomique ou macroéconomique de la segmentation et, à s'interroger sur le rôle réel tenu par les firmes dans le processus. Déterminant pour la théorie, ce rôle est à repenser selon la réponse apportée à notre question.

  10. Fungsi Metabolisme Dan Sintesis Pada Jaringan Kambium

    OpenAIRE

    Utomo, Budi

    2008-01-01

    132305100(3) Hutan merupakan areal penghasil energi yang paling produktif di dunia. Hutan mampu menghasilkan dan mengumpulkan energi setiap tahunnya (Lehninger, 1965; Whittaker, 1975). Proses pembentukan energi diawali dengan pengubahan energi dari cahaya matahari menjadi energi kimia dalam bentuk ikatan kimia yang stabil melalui proses fotosintesis. Banyak orang menganggap agregat berguna tersebut sebagai ikatan kimia kayu yang stabil.

  11. META-ANALYSIS OF THE SCIENTIFIC CONTENTS OF MATERIA SOCIO-MEDICA JOURNAL IN THE PERIOD 2009-2015.

    Science.gov (United States)

    Masic, Izet; Begic, Edin; Zunic, Lejla; Donev, Doncho

    2016-02-01

    Materia Socio Medica Journal has a long history. It was founded in 1978. To evaluate journal articles in 2015 and compare findings to previous years. The study has retrospective and descriptive character, and included the period 2009-2015. A total of 99 articles were published in Materia Socio Medica during 2015 and it shows an upward trend during the period 2009-2015. Original articles are present in majority during the last seven years (69,2%). Analyzing the last seven years, 44,1% of articles were from the field of clinical medicine. Articles from the fields of public health show an upward trend during the last four years. Collaboration rate in 2015 was 0,95. Authors of the articles are from ten countries (four continents). H index of journal is 8 and g index is 12 (Publish or Perish software). According to GoogleScholar, h5 index for Materia Socio Medica is 8 and h5 median is 9. The objectives of the journal in the next year are: to become a part of the Scopus and Web of Science databases, further internationalization and promotion of the journal in the country and the region, revision and broadening of the Editorial Board, trying to follow trend in reducing the number of days required for a decision on acceptance or revision of article and involvement of the younger generation of professionals and scientists into the journal work and publishing scope, which will lead to emergence of new enthusiasm and ideas (Journal intends to follow the trends of modern biomedical publishing worldwide).

  12. META-ANALYSIS OF THE SCIENTIFIC CONTENTS OF MATERIA SOCIO-MEDICA JOURNAL IN THE PERIOD 2009–2015

    Science.gov (United States)

    Masic, Izet; Begic, Edin; Zunic, Lejla; Donev, Doncho

    2016-01-01

    Introduction: Materia Socio Medica Journal has a long history. It was founded in 1978. Aim: To evaluate journal articles in 2015 and compare findings to previous years. Material and methods: The study has retrospective and descriptive character, and included the period 2009-2015. Results: A total of 99 articles were published in Materia Socio Medica during 2015 and it shows an upward trend during the period 2009-2015. Original articles are present in majority during the last seven years (69,2%). Analyzing the last seven years, 44,1% of articles were from the field of clinical medicine. Articles from the fields of public health show an upward trend during the last four years. Collaboration rate in 2015 was 0,95. Authors of the articles are from ten countries (four continents). H index of journal is 8 and g index is 12 (Publish or Perish software). According to GoogleScholar, h5 index for Materia Socio Medica is 8 and h5 median is 9. Conclusions: The objectives of the journal in the next year are: to become a part of the Scopus and Web of Science databases, further internationalization and promotion of the journal in the country and the region, revision and broadening of the Editorial Board, trying to follow trend in reducing the number of days required for a decision on acceptance or revision of article and involvement of the younger generation of professionals and scientists into the journal work and publishing scope, which will lead to emergence of new enthusiasm and ideas (Journal intends to follow the trends of modern biomedical publishing worldwide). PMID:27047258

  13. The Doctrine of Signatures, Materia Medica of Orchids, and the Contributions of Doctor - Orchidologists.

    Science.gov (United States)

    Pearn, John

    2012-12-01

    The heritage of medicine is written in many forms. One repository is to be found in the history of orchids, the world's largest family of flowering plants. Orchids were so named by Theophrastus (c.372-288 BC) who recorded their medicinal use as an aphrodisiac and the promoter of virility, in the context of the Doctrine of Signatures. Such use endured for millennia, and was recorded both by Paracelsus (1493-1551) and Linnaeus (1707-1778). The history of orchidology and medicine are entwined in four domains: (a) orchids and their historical materia medica, within the paradigm of the Doctrine of Signatures; (b) the enduring and extensive contemporary medicinal and culinary use of orchids such as Vanilla and salep extracts of Orchis; (c) the scientific contributions of doctors as orchidologists; and (d) the heritage of more than a hundred doctors' names in the scientific etymology of the Orchidaceae family. Prominent orchidologists have included the Scottish doctor-soldier and botanist, Robert Brown (1773-1858); the Director of the State Herbarium at Leyden and the Rijks Museum, Carl Ludwig Blume (1796-1862); and Dr William Sterling MD (1888-1967). Among the more than 1250 genus names (and 33,000 species) of orchids are the names of more than a hundred doctors, their lives and works perpetuated in the scientific etymology of this family of exotic, beautiful, flamboyant, intriguing and often expensive flowers. Generic names record the lives and works of such as Aristotle (384-322BC) in Aristotelia Loureiro 1790; Cadet de Gassicourt (1769-1821) in Cadetia Gaudichaud 1826; Sir Joseph Dalton Hooker (1817-1911) in Sirhookera O. Kuntze 1891; and Dr Theodore Daniel Vrydag Zynen (fl. 1820-1850) in Vrydagzynea Blume 1858. One of the principal horticultural genera of orchids, Brassavola, records the life and work of the Ferrara and Padua physician and botanist, Antonio Musa Brassavola (1500-1555). The first Slipper Orchid bred as a hybrid, Paphiopedilum harrisianum (by John

  14. [Good agricultural practice (GAP) of Chinese materia medica (CMM) for ten years: achievements, problems and proposals].

    Science.gov (United States)

    Guo, Lan-Ping; Zhang, Yan; Zhu, Shou-Dong; Wang, Gui-Hua; Wang, Xiu; Zhang, Xiao-Bo; Chen, Mei-Lan; He, Ya-Li; Han, Bang-Xing; Chen, Nai-Fu; Huang, Lu-Qi

    2014-04-01

    This paper aims to summarize the achievements during the implementation process of good agricultural practice (GAP) in Chinese Materia Medica (CMM), and on basis of analyzing the existing problems of GAP, to propose further implementation of GAP in TCM growing. Since the launch of GAP in CMM growing ten years ago, it has acquired great achievements, including: (1) The promulgation of a series of measures for the administration of the GAP approval in the CMM growing; (2) The expanded planting area of CMM; (3) The increased awareness of standardized CMM growing among farmers and enterprises; (4) The establishment of GAP implementation bases for CMM growing; (5) The improvement of theory and methodology for CMM growing; (6) The development of a large group of experts and scholars in GAP approval for CMM production. The problems existing in the production include: (1) A deep understanding of GAP and its certification is still needed; (2) The distribution of the certification base is not reasonable; (3) The geo-economics effect and the backward farming practices are thought to be the bottlenecks in the standardization of CMM growing and the scale production of CMM; (4) Low comparative effectiveness limits the development of the GAP; (5) The base of breeding improved variety is blank; (6) The immature of the cultivation technique lead to the risk of production process; (7) The degradation of soil microbial and the continuous cropping obstacle restrict the sustainable development of the GAP base. To further promote the health and orderly GAP in the CMM growing, the authors propose: (1) To change the mode of production; (2) To establish a sound standard system so as to ensure quality products for fair prices; (3) To fully consider the geo-economic culture and vigorously promote the definite cultivating of traditional Chinese medicinal materials; (4) To strengthen the transformation and generalization of basic researches and achievements, in order to provide technical

  15. [Study on processing adjuvant medicines in Lei Gong's treatise on preparation and broiling of materia medica (Leigong Paozhi Lun)].

    Science.gov (United States)

    Zhang, Wei; Zhang, Ruixian

    2010-09-01

    There were 268 kinds of medicines recorded in the book of Lei Gong's Treatise on preparation and broiling of materia medica (Leigong Paozhi Lun). Among these medicines, 178 medicines were prepared with adjuvant medicines, including general and special compatible adjuvant medicines. These adjuvant medicines used in this book can be explained by the theory of "seven-relation compatibility". The author tried to explain the usage and their compatibility of these adjuvant medicines and put forward that attention should be paid to the changes in functions of medicines and the influences of society should be paid attention.

  16. [Analysis of projects funded by NSFC in field of processing Chinese materia medica in recent five years].

    Science.gov (United States)

    Chen, Lei; Xia, Xing; He, Bo-sai; Hah, Li-wei

    2015-05-01

    The general situation of the approved and concluded projects of National Natural Science Foundation of China in the field of processing Chinese Materia Medica in recent five years has been reviewed. The progresses and achievements of some projects have been summarized in accordance with research area such as the processing principle, the processing technology, quality evaluation, toxicity and safety evaluation, etc. The researchers and project support units of the funded projects have been analyzed, and the problems of the applications have been also summarized.

  17. Back to the roots: A quantitative survey of herbal drugs in Dioscorides' De Materia Medica (ex Matthioli, 1568).

    Science.gov (United States)

    Staub, P O; Casu, L; Leonti, M

    2016-09-15

    De Materia Medica written by Pedanios Dioscorides (1 century CE) has shaped European and Mediterranean herbal medicine to a large extent. Despite its fundamental importance for modern medico-botanical traditions the content of this work has never been systematically assessed. We present a quantitative survey of the botanical drugs described in De Materia Medica (ex Matthioli, 1568) and identify overall therapeutic, diachronic and botanical patterns. The extracted data may serve as a baseline and help to better contextualize research on herbal drugs and phytotherapy. Therapeutic uses of herbal drugs were extracted through line-by-line reading of a digitized version of the treatise. For each plant usage mentioned in the text we recorded (I) the chapter number, (II) the putative botanical identity, (III) the plant part, (IV) the symptoms or disease, (V) the mode of administration, (VI) our biomedical interpretation of the ancient ailment or disease description as well as (VII) the organ- and symptom-defined category under which the use was filed. An introduction to Dioscorides' De Materia Medica and Matthioli's Renaissance commentary is followed by a description of the employed methodology. The results and discussion section introduces the generated database comprising 5314 unique therapeutic uses of 536 plant taxa and 924 herbal drugs. Separate subsections address salient patterns such as the frequent recommendation of Fabaceae seeds for dermatology, Apiaceae seeds as antidotes and Apiaceae exudates for neurology and psychosomatic disorders as well as the heavy reliance on subterranean parts as drugs. The therapeutic knowledge described in De Materia Medica (ex Matthioli, 1568) offers unique insights into classical Mediterranean epidemiology and herbal medicine. Drugs that lost importance over time as well as remedies used for diseases now controlled by preventive medicine and industrially produced drugs may be interesting starting points for research on herbal

  18. Un Nouveau Monde du Savoir

    International Development Research Centre (IDRC) Digital Library (Canada)

    Si les effets de la mondialisation sur l'économie, la politique ou encore les ..... Il souligne l'importance cruciale d'un plan stratégique d'internationalisation, ...... Lors du recrutement de nouveaux professeurs ( lorsque cette situation est ...

  19. rive gauche du fleuve Rimac

    International Development Research Centre (IDRC) Digital Library (Canada)

    tégée du fleuve et les terrains vagues d'une zone industrielle. .... Ces deux diagnostics sont d'importants outils qui contri- bueront à une meilleure planification ... conditions et instruments nécessaires pour améliorer la situation financière des ...

  20. Voorwoord Forward | du Plessis | Lexikos

    African Journals Online (AJOL)

    J.CM.D. du Plessis. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions ...

  1. Charte du Conseil des Gouverneurs

    International Development Research Centre (IDRC) Digital Library (Canada)

    Office 2004 Test Drive User

    7. favoriser des communications ouvertes et franches entre le personnel, la direction ..... de dresser le procès-verbal des réunions du Conseil et de ses comités et de veiller à ce ... et des résultats qu'il obtient, et non de sa gestion quotidienne.

  2. Bases biologiques du comportement social

    CERN Document Server

    Laborit, H

    1994-01-01

    Pour bien comprendre le comportement humain dans un environnement social,il est necessaire de comprendre comment fonctionne le systÂ?me nerveux central. L'une des principales fonctions du cerveau est de crÂ?er des relations entre leshumains.. .................

  3. Paul Celan in Translation: "Du sei wie du"

    Directory of Open Access Journals (Sweden)

    John Felstiner

    1983-09-01

    Full Text Available Translating the lyric poetry of Paul Celan, especially his later poems, carries not only the endemic challenge and difficulty of any verse translation, but the added incentive of doing justice to a writer whose whole recourse after the Holocaust—whose sanctuary, if he was to have any at all—he sought in language itself, specifically in the Muttersprache , the mother tongue that was as well the tongue of those who murdered his mother and father. This essay exposes a process of translating "Du sei wie du" (1970, which perhaps more than any other poem by Celan, at once solicits and defies translation, moving as it does from modern to medieval German, and closing with Hebrew words from Isaiah— a messianic imperative that shows Celan verging as ever on his Jewish identity.

  4. Le parcours migratoire de jeunes ruraux du bled du kif

    Directory of Open Access Journals (Sweden)

    Khalid Mouna

    2015-06-01

    Full Text Available Cet article analyse le parcours migratoire des jeunes ruraux originaires des zones de production du cannabis, jeunes qui cherchent à briser les chaînes de soumission et d’humiliation vécues au quotidien. Pour les jeunes concernés par notre étude, la migration constitue un moyen de s’intégrer dans des réseaux transnationaux et ainsi d’entamer une carrière de beznass (commerçant du cannabis. Ce parcours « initiatique » permet à ces jeunes de revenir au bled avec de nouvelles idées, des moyens accrus, et de jouer un rôle actif dans l’économie locale – qui reste pour eux focalisée sur la production de cannabis, cette dernière restant néanmoins officiellement interdite.

  5. Bassins versants du Loup, de la Cagne et du Malvan

    OpenAIRE

    Lepère, Cédric; Lautier, Laurence; Pellegrino, Emmanuel

    2013-01-01

    Identifiant de l'opération archéologique : 8453 Date de l'opération : 2007 (PC) ; 2007 (PI) Inventeur(s) : Lepère Cédric (AUT) ; Lautier Laurence (AUT) ; Pellegrino Emmanuel (AUT) Une campagne de prospection inventaire a été effectuée pendant trois mois, dans les bassins-versants de la Cagne, du Loup et du Malvan qui regroupent les communes de Cagnes-sur-Mer, Villeneuve-Loubet, La Colle-sur-Loup, Saint-Paul-de-Vence, Vence, Saint-Jeannet, Bezaudun, Tourrettes-sur-Loup, Roquefort-les-Pins, Le ...

  6. Rosacea and contact allergy to cosmetics and topical medicaments--retrospective analysis of multicentre surveillance data 1995-2002.

    Science.gov (United States)

    Jappe, U; Schnuch, A; Uter, W

    2005-02-01

    The role of contact allergy in rosacea has rarely been investigated. In this retrospective study, 361 out of 76,697 patients tested and documented by the Information Network of Departments of Dermatology between 1995 and 2002 had rosacea. Patch tests included standard series and constituents of cosmetics and topical medicaments. 118/361 had additionally been patch tested with their own cosmetics/medicaments. Positive reactions occurred to nickel (II) sulfate in 9.3%, fragrance mix in 8.8%, thimerosal in 6.9%, Myroxylon pereirae resin in 5.9%, potassium dichromate in 4.6% and propolis in 2.8%. Whereas rosacea patients had a significantly higher risk of contact allergy to propolis compared to the remaining patients, in an age- and sex-adjusted analysis, contact allergy to nickel was significantly less frequent in this group. For Lyral, the risk was elevated, albeit not significantly. Only 2/329 patients were positive to neomycin sulfate and 1/100 to gentamicin sulfate, among the panel of (topical) antibiotics tested. Among 118 patients tested with their own products, 3 were tested to metronidazole, 1 reacting positively. Irritant or doubtful patch test reactions were provoked by various substances (vehicles, oxidants and preservatives of various creams), which might also be clinically important, considering the heightened sensitivity of rosaceous skin.

  7. Clinical and radiographical evaluation of mineral trioxide aggregate, biodentine and propolis as pulpotomy medicaments in primary teeth

    Directory of Open Access Journals (Sweden)

    Bharti Kusum

    2015-11-01

    Full Text Available Objectives The purpose of this study was to evaluate the efficacy of mineral trioxide aggregate (MTA, Biodentine and Propolis as pulpotomy medicaments in primary dentition, both clinically and radiographically. Materials and Methods A total of 75 healthy 3 to 10 yr old children each having at least one carious primary molar tooth were selected. Random assignment of the pulpotomy medicaments was done as follows: Group I, MTA; Group II, Biodentine; Group III, Propolis. All the pulpotomized teeth were evaluated at 3, 6, and 9 mon clinically and radiographically, based on the scoring criteria system. Results The clinical success rates were found to be similar among the three groups at 3 and 6 mon where as a significant decrease in success rate was observed in Group III (84% compared to both Group I (100% and Group II (100% at 9 mon. Radiographic success rates over a period of 9 mon in Groups I, II, and III were 92, 80, and 72%, respectively. Conclusions Teeth treated with MTA and Biodentine showed more favorable clinical and radiographic success as compared to Propolis at 9 mon follow-up.

  8. [Effect of multicomponent environment on intestinal permeability of puerarin in biopharmaceutics classification system of Chinese materia medica].

    Science.gov (United States)

    Liu, Yang; Wang, Gang; Dong, Ling; Tang, Ming-Min; Zhu, Mei-Ling; Dong, Hong-Huant; Hou, Cheng-Bo

    2014-12-01

    The evaluation of permeability in biopharmaceutics classification system of Chinese materia medica (CMMBCS) requires multicomponent as a whole in order to conduct research, even in the study of a specific component, should also be put in the multicomponent environment. Based on this principle, the high content components in Gegen Qinlian decoction were used as multicomponent environmental impact factors in the experiment, and the relevant parameters of intestinal permeability about puerarin were measured with using in situ single-pass intestinal perfusion model, to investigate and evaluate the intestinal permeability of puerarin with other high content components. The experimental results showed that different proportions of baicalin, glycyrrhizic acid and berberine had certain influence on intestinal permeability of puerarin, and glycyrrhizic acid could significantly inhibit the intestinal absorption of puerarin, moreover, high concentration of berberine could promote the absorption of puerarin. The research results indicated that the important research ideas of permeability evaluation in biopharmaceutics classification system of Chinese materia medica with fully considering the effects of other ingredients in multicomponent environment.

  9. GC-MS analysis and antimicrobial activity determination of Citrus medica L. var proper leaf essential oil from South Sulawesi against skin pathogen microorganism

    Science.gov (United States)

    Aliyah; Himawan, A.; Rante, H.; Mufidah; Ningsih, D. R.

    2017-11-01

    A research about Citrus medica L. var sarcodactylis had been conducted and it showed a significant antimicrobial activity, thus drive our curiosity to investigate the other variety from the same species, Citrus medica L. var proper. This research focuses in chemical compound study and antimicrobial activity screening against Staphylococcus aureus, Propionibacterium acne, and Candida albicans of Citrus medica L. var Proper leaves’ essential oil. The essential oil is distillated from fresh leaves by hydrodestillation. The chemical compound was analysed using GC-MS instrument while the antimicrobial activity was tested using disk diffusion method. The results showed that the major component of the essential oil was Z-citral, citral and limonene compounds. The antimicrobial activity test results against the test microorganism are 9.15±0.15 mm, 11.15±1.3 mm and 8.02±0.48 mm, consecutively, for Staphylococcus aureus, Propionibacterium acne and Candida albicans.

  10. [Inheritance on and innovation of traditional Chinese medicine (TCM) flavor theory and TCM flavor standardization principle flavor theory in Compendium of Materia Medica].

    Science.gov (United States)

    Zhang, Wei; Zhang, Rui-xian; Li, Jian

    2015-12-01

    All previous literatures about Chinese herbal medicines show distinctive traditional Chinese medicine (TCM) flavors. Compendium of Materia Medica is an influential book in TCM history. The TCM flavor theory and flavor standardization principle in this book has important significance for modern TCM flavor standardization. Compendium of Materia Medica pays attention to the flavor theory, explain the relations between the flavor of medicine and its therapeutic effects by means of Neo-Confucianism of the Song and Ming Dynasties. However,the book has not reflected and further developed the systemic theory, which originated in the Jin and Yuan dynasty. In Compendium of Materia Medica , flavor are standardized just by tasting medicines, instead of deducing flavors. Therefore, medicine tasting should be adopted as the major method to standardize the flavor of medicine.

  11. Marche du foncier urbain et promotion du logement au Benin ...

    African Journals Online (AJOL)

    Le marché du foncier urbain au Bénin est un secteur qui met en jeu l'intervention de plusieurs acteurs publics et privés mais également de l'informel. La notion de « foncier urbain » utilisée dans cet article englobe les acceptions et les utilisations faites en architecture, en urbanisme, en aménagement et en gestion urbaine.

  12. Gestion du parc agroforestier du terroir de Vipalogo (Burkina Faso ...

    African Journals Online (AJOL)

    Au Burkina Faso, l'arbre rural fait partie des systèmes de production. Le choix des espèces, leur densité, les modes de gestion ainsi que les besoins à satisfaire, obéissent à des critères propres aux producteurs. C'est pour comprendre ces logiques paysannes de la gestion du parc agroforestier que la présente étude a été ...

  13. Malformations du tube neural en chirurgie pediatrique du chu de ...

    African Journals Online (AJOL)

    encéphalocèle et 6 cas de sipina bifida. La cure chirurgicale a été le principal mode de prise en charge des patients. Seuls 91,38% des cas ont été opérés. Pour toutes les malformations du tube neural, nous avons enregistré 7 décès dont 2 décès ...

  14. [Investigation on pattern and methods of quality control for Chinese materia medica based on dao-di herbs and bioassay - bioassay for Coptis chinensis].

    Science.gov (United States)

    Yan, Dan; Xiao, Xiao-he

    2011-05-01

    Establishment of bioassay methods is the technical issues to be faced with in the bioassay of Chinese materia medica. Taking the bioassay of Coptis chinensis Franch. as an example, the establishment process and application of the bioassay methods (including bio-potency and bio-activity fingerprint) were explained from the aspects of methodology, principle of selection, experimental design, method confirmation and data analysis. The common technologies were extracted and formed with the above aspects, so as to provide technical support for constructing pattern and method of the quality control for Chinese materia medica based on the dao-di herbs and bioassay.

  15. [Classes of crude drugs and its distribution of producing area in the attached illustrations in Ben cao tu jing (Illustrated Classic of Materia Medica)].

    Science.gov (United States)

    Xu, T; Peng, H S

    2016-03-01

    Ben cao tu jing (Illustrated Classic of Materia Medica) is the earliest extant atlas book of materia medica in China, with 933 attached drawings. Among them, the largest portion, amounting to 670, are herbaceous plants, mostly commonly used, with definite marks of the origin producing areas, distributed across 149 administrative divisions(prefectures and counties) of the Song Dynasty, most of them in Northern area which were distributed denser than those in Southern area. The densest ones were located in Southern Shanxi, Eastern Sichuan and Eastern Anhui. In the attached drawings, the frequency of highest occurrence appeared in this Classic are three prefectures, Chuzhou, Shizhou and Guangzhou.

  16. L’Harmonie du monde

    Directory of Open Access Journals (Sweden)

    Martine Clouzot

    2003-11-01

    Full Text Available La Bourgogne est particulièrement bien présente et représentée dans l’exposition sur la musique et ses représentations au Moyen Âge organisée par Isabelle Marchesin (université de Poitiers, Christine Laloue (conservatrice du Patrimoine au Musée et Martine Clouzot (université de Bourgogne, au Musée de la Musique à Paris du 26 mars au 27 juin 2004. En Côte-d’Or, à Dijon, la Bibliothèque municipale a donné son accord officiel pour le prêt de la Bible d’Etienne Harding, les Moralia in Job et u...

  17. Les vicissitudes du fret ferroviaire

    OpenAIRE

    DABLANC, L

    2010-01-01

    Dans beaucoup de pays européens, et plus encore en Amérique du Nord et en Asie, le transport de marchandises par le train a augmenté depuis dix ans. Cette activité réduit la part des marchandises acheminées par la route et contribue ainsi au développement durable : un camion émet 8 à 30 fois plus de dioxyde de carbone que le train, pour une distance et une quantité transportée équivalentes. Pourtant, la France a raté ce renouveau. Filiale du groupe public SNCF, la Société Fret SNCF, qui assur...

  18. L'energie du moustique

    CERN Document Server

    Augereau, J F

    2002-01-01

    ENSEMBLE DE QUATRE ARTICLES - LARGE HADRON COLLIDER: Le dernier accelerateur de particules du CERN, le LEP, produisait des faisceaux d'electrons de 100 GeV chacun. Le LHC, qui accelere des faisceaux de protons, leur communiquera une energie de 7 TeV chacun. Une energie a la fois colossale et derisoire. Un TeV represente a peu pres l'energie cinetique d'un moustique (1/2 page).

  19. Revision des Symphurus du Siboga

    NARCIS (Netherlands)

    Chabanaud, Paul

    1955-01-01

    Ce m’est un devoir particulièrement agréable que de saisir l’occasion de ce petit mémoire pour remercier M. L. F. DE BEAUFORT, M. H. ENGEL, Directeur du Zoologisch Museum, ainsi que M. J. J. HOEDEMAN de l’accueil qu’à diverses reprises, j’ai reçu de leur part, au Zoölogisch Museum, et aussi des

  20. Actes des 5èmes Journées Scientifiques du GDR3544 Sciences du Bois. Journées Annuelles du GDR 3544 Sciences du Bois

    OpenAIRE

    CHAPLAIN, Myriam; CARE, Sabine; GRIL, Joseph

    2016-01-01

    Le Groupement de Recherche en Sciences du bois (GDR3544 Sciences du Bois) a été créé en 2012 par le CNRS et renouvelé en 2016 pour 5 ans. La mission de ce groupement est : (1) de structurer la recherche sur le bois en France pour lui donner une visibilité nationale, (2) de contribuer au développement de la formation en sciences du bois et (3) de servir de relai aux réseaux internationaux de sciences du bois. Les 5èmes journées annuelles du GDR Bois ont été organisées à Bordeaux, au domaine du...

  1. Original Paper Performances comparées du HDL-cholestérol et du ...

    African Journals Online (AJOL)

    CT/HDL-C) et du HDL-Cholestérol est le meilleur prédicteur du SMet chez les adultes béninois. .... (Canada) et du. Ministère de la Santé du Bénin. Le consentement éclairé écrit a été obtenu de chaque participant avant leur recrutement dans.

  2. [Applications and spproved projects of general program, young scientist fund and fund for less developed region of national natural science funds in discipline of Chinese materia medica, NSFC in 2011].

    Science.gov (United States)

    Han, Liwei; Wang, Yueyun; He, Wenbin; Zhang, Junjie; Bi, Minggang; Shang, Hongcai; Shang, Deyang; Wang, Chang'en

    2012-03-01

    The applications accepted and approved by general program, young scientist fund and fund for less developed region of national natural science funds in the discipline of Chinese materia medica, NSFC in 2011 have been introduced. The character and problems in these applications have been analyzed to give a reference to the scientists in the field of Chinese material medica.

  3. 35 Typologie des eaux de surface du bassin du Sebou par multi ...

    African Journals Online (AJOL)

    PR BOKO

    2Service de protection de la qualité de l'eau, Agence du Bassin Hydraulique du ... pour montrer l'évolution de la qualité biologique des eaux de surface du ..... Biological Indicators of Freshwater Pollution and Environmental Management,.

  4. Régionalisation du recrutement du personnel de santé au Burkina ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Régionalisation du recrutement du personnel de santé au Burkina Faso ... le ministère a adopté une politique de recrutement régionalisé de certaines catégories du ... de comprendre le contexte dans lequel une telle stratégie a été formulée, ...

  5. La disparition du temps en gravitation quantique

    OpenAIRE

    Saint-Ours, Alexis de

    2012-01-01

    Le but de ce travail est d’examiner l’incidence philosophique de la gravitation quantique sur le concept de temps. Je cherche à montrer qu’elle conduit à une disparition du temps comme dimension et ouvre la voie à une compréhension du temps comme variation et même à l’idée de variation pure. En l’absence de temps mécanique, il est cependant possible de définir un temps d’origine thermodynamique. Je montre en quoi cette dissociation du temps mécanique et du temps thermodynamique, fait écho à l...

  6. Au fil du temps (1976 ou la loi du seuil

    Directory of Open Access Journals (Sweden)

    Isabelle Singer

    2010-04-01

    Full Text Available Ayant choisi de vivre dans un camion, les héros d’Au fil du temps (film de Wim Wenders de 1976 font du seuil une expérience particulière. Celle de la rupture avec toute idée de foyer et celle du refus d’appartenance à la terre natale, cette terre allemande traversée par une frontière le long de laquelle ils vont voyager, et qui les renvoie à chaque instant aux traumatismes de l’Histoire. Sur le pare-brise du camion, l’extérieur (campagnes indifférenciées, villes à l’abandon… et l’intérieur se superposent. Au fil du temps questionne le paysage : il s’agit d’en décoller un à un les mythes qui le recouvrent. L’image alors n’est plus surface mais volume à traverser, à lacérer et découvrir ce qui est tissé dans le paysage. La démarche de Wenders est alors proche de celle d’un de ses contemporains : Anselm Kiefer. Le paysage allemand provoque le rejet parce qu’il y a là toujours plus que le visible : des strates et des strates de culpabilité que le mythe - et c’est sa fonction - a recouvert. Et qu’il s’agira ici, de soulever. Le choix du nomadisme, c’est celui d’un état de l’humanité antérieur à l’idée de patrie. Et c’est aussi celui de la solitude, comme prix à payer à ce refus d’appartenance et à cette mise à jour des mythes. L’appartenance à la terre allemande et à son Histoire est profondément problématique parce que les pères sont fondamentalement coupables. On se reconnaîtra alors des pères de substitution : des pères de cinéma (Nicholas Ray ou Fritz Lang. Et l’on substituera l’Histoire du cinéma à l’Histoire. Bruno est réparateur ambulant de projecteurs et Au fil du temps dressera, au gré de ses pérégrinations, un état des lieux du cinéma allemand des années soixante-dix : déliquescent, colonisé par les images hollywoodiennes. Il faut que cela change : état du cinéma ; état des protagonistes solitaires en quête d’une identit

  7. Comparison of the removal of calcium hydroxide medicaments on the root canal treatment irrigated with manual and sonic agitation technique

    Directory of Open Access Journals (Sweden)

    Anna Muryani

    2017-11-01

    Full Text Available Introduction: Irrigation of the root canal system is an important part of the endodontic treatment principle which aims to improve the hygiene of the root canal system from any debris and medicament residue with the hydrodynamic system. Root irrigation technique can be done with the manual and sonic system by using 2.5% NaOCI irrigation solution. Calcium hydroxide is used as a medicament for root canal sterilization. Root canal treatment will fail due to the imperfect removal of calcium hydroxide residue. The objective of this research was to analyze the comparison of the removal of calcium hydroxide medicaments on the root canal treatment irrigated with manual and sonic agitation technique using 2.5% sodium hypochlorite solution. Methods: The methods used in this study was experimental laboratory. The sample used was 30 maxillary incisors. The teeth were then divided into two groups randomly, then the root canal preparation was done by the crown down technique with manual irrigation using 2.5% NaOCI solution. The radicular part of the teeth was then split longitudinally, given a standardized groove in the one-third of the apical part, then applied with water-solved calcium hydroxide. The teeth were unified afterwards by using flowable composites, then soaked in the artificial saliva at the temperature of 37ºC. The sample of the 1st group was irrigated by manual agitation technique, and the sample of the 2nd group 2 was irrigated by sonic agitation technique, then both were viewed by stereo microscope. The data results were analyzed by Kruskal-Wallis and Mann-Whitney tests. Results: The results of calcium hydroxide removal were different between the root canals that were irrigated using 2.5% sodium hypochlorite irrigation solution by manual agitation technique compared to the sonic agitation technique. Irrigation using 2.5% sodium hypochlorite irrigation solution with the sonic agitation techniques were proven to be more effective in lifting Ca

  8. Twenty years of society of medical informatics of b&h and the journal acta informatica medica.

    Science.gov (United States)

    Masic, Izet

    2012-03-01

    In 2012, Health/Medical informatics profession celebrates five jubilees in Bosnia and Herzegovina: a) Thirty five years from the introduction of the first automatic manipulation of data; b) Twenty five years from establishing Society for Medical Informatics BiH; c) Twenty years from establishing scientific and professional journal of the Society for Medical Informatics of Bosnia and Herzegovina "Acta Informatica Medica"; d) Twenty years from establishing first Cathdra for Medical Informatics on biomedical faculties in Bosnia and Herzegovina and e) Ten years from the introduction of "Distance learning" in medical curriculum. All of the five mentioned activities in the area of Medical informatics had special importance and gave appropriate contribution in the development of Health/Medical informatics in Bosnia And Herzegovina.

  9. [The significance of drawing on experience of experimental study on Chinese materia medica during the Republican period].

    Science.gov (United States)

    Li, Nan; Wan, Fang

    2015-05-01

    During the period of the Republic of China, researches of experiments on Chinese materia medica developed extensively with the scientific process of Chinese medicine. Although the technology standard was relatively low and the reference value, limited. The experiences, positive or negative, obtained at that time still has reference significance to today's Chinese medicine scientific research. The notion that traditional Chinese medical and scientific research be conducted under the guidance of TCM theory; valuable experience contained in the ancient literature of traditional Chinese medicine be collected; and the transformation capacity of scientific research be elevated, has been accepted by modern TCM professionals. If you go back to the history, it can be seen that this notion was summarized through repeated practice during the critical moment of traditional Chinese medicine, which should be emphasized and its understanding deepened at any time.

  10. [Study on supply and demand relation based on two stages division of market of Chinese materia medica].

    Science.gov (United States)

    Yang, Guang; Guo, Lan-Ping; Wang, Nuo; Zeng, Yan; Huang, Lu-Qi

    2014-01-01

    The complex production processes and long industrial chain in traditional Chinese medicine (TCM) market result in difficulty in Chinese market microstructure research. Based on the defining the logical relationships among different concepts. This paper divides TCM market into two stages as Chinese materia medica resource market and traditional Chinese Patent Medicines market. Under this foundation, we investigated the supply capacity, approaching rules and motivation system of suppliers in TCM market, analyzed the demand situation in the perspective of demand side, and evaluated the purchasing power in terms of population profile, income, and insurance. Furthermore we also analyzed the price formation mechanism in two stages of TCM market. We hope this study can make a positive and promotion effect on TCM market related research.

  11. Le vide univers du tout et du rien

    CERN Document Server

    Diner, Simon

    1997-01-01

    Pourquoi l'Univers plutôt que le vide ? Le temps et l'espace existent-ils en l'absence de l'Univers ? Que reste-t-il quand tout est enlevé ? Pourquoi quelque chose plutôt que rien ? Depuis des siècles, ces interrogations mobilisent philosophes et physiciens. Mais aujourd'hui, le vide n'est pas le rien. Il serait même l'acteur central de l'histoire de la matière et de l'Univers, le partenaire privilégié de la physique. Vide et matière ne sont plus deux manifestations séparées de la nature, mais deux aspects d'une même réalité. Le vide est l'état de base dont la matière émerge, sans couper son cordon ombilical Le vide comme Univers du rien cède la place au vide comme Univers du tout. Que le vide puisse être conçu par les physiciens comme réservoir potentiel d'univers, voici qui ne devrait laisser personne indifférent. Ce livre ouvre un débat et nous convie à une réflexion surprenante.

  12. Image du savoir, image du pouvoir dans le Lapidaire

    Directory of Open Access Journals (Sweden)

    Marta LACOMBA

    2007-01-01

    Full Text Available À travers le prologue et les enluminures de présentation, le Lapidaire d’Alphonse X oriente l’interprétation de l’œuvre. Ces paratextes mettent en avant le rôle capital du savoir, représenté par la métaphore du trésor caché, qui a ici une valeur topique. Ils mettent également en exergue le rôle que s’attribue le roi dans la transmission de ce savoir, et placent cette nouvelle attribution royale au cœur de son projet politique.A través del prólogo y las miniaturas de presentación, el Lapidario de Alfonso X orienta la interpretación de la obra. Estos paratextos subrayan el papel capital del saber, representado por la metáfora del tesoro escondido, que tiene aquí un valor tópico. Ponen asimismo de manifiesto el papel que se atribuye el monarca en la transmisión de ese saber y colocan esta nueva atribución real en el centro de su proyecto político.

  13. Main: 1DU5 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1DU5 トウモロコシ Corn Zea mays L. Zeamatin Precursor. Name=Zlp; Zea Mays Molecule: Zeamatin; Chai...eta Sandwich SWS:ZEAM_MAIZE,P33679|EMBL; U06831; AAA92882.1; -.|PIR; T02075; T02075.|PDB; 1DU5; X-ray; A/B=22-227.|Mai

  14. les cahiers du cread: About this journal

    African Journals Online (AJOL)

    les cahiers du cread: About this journal. Journal Home > les cahiers du cread: About this journal. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. People. » Contact. Policies.

  15. Les figures multiples du maire.

    Directory of Open Access Journals (Sweden)

    Olivier Lebraud

    2004-06-01

    Full Text Available Alors même que l’ensemble du personnel gouvernemental et parlementaire est sujet à une relative désaffection de la part des citoyens, les maires français jouissent, on le sait, d’une popularité qui fait d’eux les figures centrales de la scène politique. Au-delà de la décentralisation, qui a souvent renforcé leur image de décideurs, ils ont su tirer parti de la dimension identitaire qui caractérise l’échelon communal pour devenir les acteurs indispensables de la vie locale. ...

  16. Vers une anthropologie du Confucianisme

    OpenAIRE

    Rieu , Alain-Marc

    2010-01-01

    Research in Anthropology developed in France by Jean-Pierre Vernant, Marcel Détienne and Philippe Descola opens the possibility to reframe the debate and research on the function of Confucianism in Chinese culture, history and society. This paper shows how Confucianism can be studied as a "mythology"; La fonction du Confucianisme dans l'histoire de la société et de la culture chinoise, les débats et les reconstructions dont il est l'objet et l'enjeu, ouvre la possibilité de l'étudier d'un poi...

  17. Session du Conseil du CERN : le ministre britannique, Robert Jackson, souligne l'intérêt de on pays pour l'avenir du CERN : décisions du Conseil pour la mise en oeuvre des recommandations du Comité d'évaluation du CERN: départ anticipé pour 200 membres au moins du personnel - mise à jour de la méthode de calcule pour les contributions des Etats Membres au budget

    CERN Multimedia

    CERN Press Office. Geneva

    1988-01-01

    Session du Conseil du CERN : le ministre britannique, Robert Jackson, souligne l'intérêt de on pays pour l'avenir du CERN : décisions du Conseil pour la mise en oeuvre des recommandations du Comité d'évaluation du CERN: départ anticipé pour 200 membres au moins du personnel - mise à jour de la méthode de calcule pour les contributions des Etats Membres au budget

  18. Bases en technique du vide

    CERN Document Server

    Rommel, Guy

    2017-01-01

    Cette seconde édition, 20 ans après la première, devrait continuer à aider les techniciens pour la réalisation de leur système de vide. La technologie du vide est utilisée, à présent, dans de nombreux domaines très différents les uns des autres et avec des matériels très fiables. Or, elle est souvent bien peu étudiée, de plus, c'est une discipline où le savoir-faire prend tout son sens. Malheureusement la transmission par des ingénieurs et techniciens expérimentés ne se fait plus ou trop rapidement. La technologie du vide fait appel à la physique, à la chimie, à la mécanique, à la métallurgie, au dessin industriel, à l'électronique, à la thermique, etc. Cette discipline demande donc de maîtriser des techniques de domaines très divers, et ce n'est pas chose facile. Chaque installation est en soi un cas particulier avec ses besoins, sa façon de traiter les matériaux et celle d'utiliser les matériels. Les systèmes de vide sont parfois copiés d'un laboratoire à un autre et le...

  19. Enige metingen over het standaard metabolisme en het actief metabolisme bij Gobiidae

    NARCIS (Netherlands)

    Penning de Vries, F.W.T.

    1969-01-01

    An attempt was made to determine the "scope for activity" -maximal active metabolism minus basal metabolism and its relation to temperature in the three species Pomatoschistus minutus,P.lozanoi and P. microps, in order to find a possible explanation for the difference in their

  20. Culture du bambou : diversification des moyens de subsistance des ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Culture du bambou : diversification des moyens de subsistance des petits producteurs de tabac du sud de la province de Nyanza, au Kenya - phase II. Au cours de la première phase du projet (projet no 103765), les chercheurs ont effectué une analyse de marché pour le bambou et les produits du bambou, comparé les ...

  1. Contribution to the study of the reduction of sulfate by the yolk sac of the chicken embryo; Contribution a l'etude de la reduction du sulfate par le sac vitellin de l'embryon de poulet

    Energy Technology Data Exchange (ETDEWEB)

    Bourgeois, Claude

    1958-11-15

    avec un rendement tres eleve. En ce qui concerne la reduction du sulfate, aucun resultat net n'a ete obtenu, hormis chez le poulet, mais peu d'especes ont ete examinees. En outre aucun embryon d'invertebres n'a fourni le moindre indice d'un metabolisme du soufre analogue a celui de l'embryon de poulet. L'embryon de poulet restait donc le seul materiel utilisable pour notre etude; l'activite reductrice du sulfate s'y trouve localisee dans le sac vitellin, organe extra embryonnaire assurant l'absorption du jaune. Quelques essais en vue d'obtenir une preparation acellulaire de sac vitellin, capable de reduire le sulfate, sont restes vains, confirmant ainsi que le systeme enzymatique implique dans la reduction est lie aux structures cellulaires, ou du moins necessite des conditions difficiles a realiser hors des cellules; ces essais nous permettent d'affirmer que dans le sac vitellin, seules les cellules epitheliales, a l'exclusion des cellules conjonctives, detiennent l'activite reductrice du sulfate. Cette impossibilite d'obtenir une preparation acellulaire active nous a conduit a etudier la reduction, in vitro, sur des sacs vitellins vides de leur jaune, ou sur des fragments de sacs vitellins, incubes a 38 deg. C. Dans ces conditions nous avons montre que l'organe etudie reduit deja le sulfate, de facon nette a l'age de 3 jours et que cette propriete persiste apres la naissance, durant la periode de resorption du sac vitellin. Enfin quelques substances agissant sur la reduction du sulfate ont ete mises en evidence: le fluorure qui a la concentration de 10{sup -2} M bloque totalement la formation de sulfite, agit a coup sur sur la penetration du sulfate dans les cellules vitellines; son action sur la reduction proprement dite est tres incertaine. L'oxygene et le cyanure de potassium au contraire agissent sur la reduction elle-meme; la privation d'oxygene l'inhibe, probablement en empechant la synthese de donateurs d'hydrogene, synthese qui intervient normalement au cours

  2. COMMUNICATION DU CREDIT AGRICOLE - French version only

    CERN Multimedia

    2003-01-01

    La Direction du Crédit Agricole informe son aimable clientèle du CERN des jours et heures d'ouverture de l'agence du site de Prévessin à compter du mardi 14 janvier 2003 : 1. Horaires pour les opérations bancaires courantes 7 jours sur 7 et 24h/24 avec l'espace libre service bancaire. 2. Horaires conseil du mardi au vendredi - Mardi, de 9h. à 12h. et de 14h.15 à 16h.30. - Mercredi, jeudi et vendredi, de 9h. à 12h. et de 13h.30 à 16h.30. Deux collaboratrices au lieu d'une seront désormais présentes toute la journée du mardi au vendredi pour vous accueillir, vous informer et vous conseiller en crédits et placements (réception conseil sur rendez-vous). Autre nouveauté : les mêmes conseillers seront aussi à votre disposition le samedi, sur notre agence de Gex, de 8h.15 à 13h.05, notamment pour les études de financements habitat. La Direction et toute l'équipe de l'agence du Crédit Agricole vous souhaitent une excellent année 2003.

  3. Nouvelles du Centre Aéré de l’Association du Personnel du CERN

    CERN Multimedia

    Jardin d'enfants

    2015-01-01

    Cet été 2015, durant quatre semaines d’été, le Centre Aéré a accueilli plus de 40 enfants âgés de 4 à 6 ans. Devant le succès rencontré, et à la demande des parents, il a été décidé d’en doubler la capacité maximale. A l'été 2016, du 4 au 29 juillet, la structure pourra accueillir les enfants de 4 ans révolus et de moins de 7 ans (nés après le 31/07/2009 mais avant  01/07/2012). Les inscriptions se feront à la semaine durant le mois d'Avril 2016. Les programmes sont en cours d'élaboration cependant nous pouvons déjà vous communiquer le thème conducteur du centre qui sera : à la découverte d'un continent différent chaque ...

  4. Coordonnateur du bureau d'assistance | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Résumé des fonctions. En tant que membre de l'équipe du Bureau d'assistance au sein de la Section du service à la clientèle (SSC), le coordonnateur du Bureau d'assistance offre au personnel du Centre et aux autres utilisateurs reconnus des installations TI du Centre un soutien de première ligne en matière d'utilisation ...

  5. La population du Moyen-Orient et de l'Afrique du Nord contribue ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    29 avr. 2016 ... Le degré d'apport au contenu varie grandement d'une population à l'autre. Si les habitants du Moyen-Orient et de l'Afrique du Nord (région MENA) utilisent Wikipédia, ils y contribuent cependant moins que les populations d'autres régions du monde. Le contenu au sujet de la région MENA est, le plus ...

  6. L'action du CRDI — le développement du secteur privé

    International Development Research Centre (IDRC) Digital Library (Canada)

    Cathy Egan

    Le CRDI est du nombre. Il reconnaît depuis longtemps la valeur de l'industrie, des échanges et du commerce comme moteurs de la croissance économique. Grâce au soutien concret qu'il a accordé au développement du secteur privé, le CRDI a appris que deux types d'aide peuvent porter fruit : améliorer le con- texte dans ...

  7. [Experience of treatment and understanding of impediment disease in Shen nong ben cao jing (Shen-ntonz's Classic of Materia Medica)].

    Science.gov (United States)

    Ding, Hongchang; Wang, Zhenrui

    2015-01-01

    As a book with significant historical materials for the research of impediment disease not to be ignored, Shen nong ben cao jing (Shennong's Classic of Materia Medica) contains, among its 365 kinds of materia medica, 75 kinds of medicines related to impediment disease. Among the latter ones, 51 are related to "damp impediment", "cold-damp impediment", "wind-cold-damp impediment", "wind impediment", "wind-damp impediment", and "cold impediment"; 16 are related to "laryngeal impediment", "general impediment", and "blood impediment"; 8 are related to "muscular impediment", "stomach impediment", "hernia-conglomeration impediment", "internal consumptive-thirst impediment", "wilting impediment", and "hemiplegic impediment". To systematically analyze the properties, tastes, and effects of these medicines and its related knowledge, and then further explore the overall recognition and their treating experience of the physicians at that period would not only enrich the historical research on impediment disease, but also offer much help and reference to the understanding and treatment of impediment for contemporary clinicians.

  8. Monnaie du commun et revenu social garanti

    OpenAIRE

    Baronian, Laurent; Vercellone, Carlo

    2015-01-01

    Le but de cet article est de poser les bases d’une approche de la monnaie du commun à partir d’une interrogation évincée par la théorie économique des biens communs. Notre analyse de la relation entre monnaie et théorie du commun s’articulera en trois parties. Dans la première, il s’agit d’établir une conception dynamique du commun au singulier dans laquelle la question de la monnaie et des mutations de la division du travail occupe une place centrale. Cette démarche fondée sur la triade trav...

  9. Paysans du Brésil

    Directory of Open Access Journals (Sweden)

    Dominique Temple

    2007-01-01

    Full Text Available Eric Sabourin, « Paysans du Brésil : Entre échange marchand et réciprocité » Paris, Editions Quae, 241p, 30 euros, (préface de Maxime Haubert, 2007Dans la présentation du livre, Maxime Haubert dit :«Cet ouvrage propose une analyse socio-anthropologique et agronomique des sociétés rurales et paysannes du Brésil et des transformations qu'elles ont connues ces dernières décennies, en particulier face aux interventions de l'Etat et à l'expansion du marché capitaliste (.... «Le livre pose d'abor...

  10. Daphne du Maurier' unustatud jutud / Udo Uibo

    Index Scriptorium Estoniae

    Uibo, Udo, 1956-

    2011-01-01

    Ajalehe "The Independent" teatel kavatseb kirjastus "Virago" maikuus avaldada Daphne Du Maurier lühiproosa kogumiku "Nukk" (The Doll), mille on koostanud tema loomingu suur austaja Ann Willmore ja mis sisaldab 13 unustatud ja seni avaldamata novelli

  11. Assessment of the potential of Allium sativum oil as a new medicament for non-vital pulpotomy of primary teeth.

    Science.gov (United States)

    Mohammad, Shukry Gamal; Baroudi, Kusai

    2015-01-01

    The objective of this study was to compare the clinical and radiographic effects of Allium sativum oil and formocresol in nonvital pulpotomy in primary teeth. Twenty children ranging in age from 4 to 8 years were included in the study. In every one of those children, pulpotomy was indicated for the primary molars. Pulpotomy procedure was performed and the radicular pulp tissue of one molar was capped with A. sativum oil in a cotton pellet while the other molar was capped with formocresol. The teeth were evaluated clinically and radiographically before and after 6 months using standard clinical and radiographic criteria. Statistically, these results revealed significant difference between the radiographic findings of nonvital pulpotomy in primary molars with the two medicaments. Statistical analysis was performed using independent t-test and paired t-test at the significance level of α = 0.05. A. sativum oil has potent antibacterial properties that enable it to combat intracanal microbes in the infected pulp of primary molars. Better results were obtained when A. sativum oil was used. A. sativum oil had more powerful effects than formocresol on the infected pulp of primary nonvital molars.

  12. Clinical and Radiographic Evaluation of Allium sativum Oil as a New Medicament for Vital Pulp Treatment of Primary Teeth.

    Science.gov (United States)

    Mohammad, Shukry Gamal; Raheel, Syed Ahmed; Baroudi, Kusai

    2014-01-01

    The objective of this study was to compare between the clinical and radiographic effects of Allium sativum oil and those of formocresol in vital pulpotomy in primary teeth. A total of 20 children age ranged from 4 to 8 years were included in the study. In every one of those children, the primary molars indicated for pulpotomy. Pulpotomy procedure was performed, and the radicular pulp tissue of one molar capped with A. sativum oil in a cotton pellet, whereas the other molar capped with formocresol, the teeth evaluated clinically and radiographically before and after 6 months, using standard clinical and radiographical criteria. Statistically, these results revealed no significant difference between the radiographic findings of vital pulpotomy in primary molars with the two medicaments was found. A. sativum oil offers a good healing potential, leaving the remaining pulp tissue healthy and functioning. Vital pulpotomy with allium sativa oil was given raise 90% success rate while that with formocresol was 85%. A. sativum oil is a biocompatible material that is compatible with vital human pulp tissue. It offers a good healing potential, leaving the remaining pulp tissue healthy and functioning.

  13. [Applications and prospects of on-line near infrared spectroscopy technology in manufacturing of Chinese materia medica].

    Science.gov (United States)

    Li, Yang; Wu, Zhi-Sheng; Pan, Xiao-Ning; Shi, Xin-Yuan; Guo, Ming-Ye; Xu, Bing; Qiao, Yan-Jiang

    2014-10-01

    The quality of Chinese materia medica (CMM) is affected by every process in CMM manufacturing. According to multi-unit complex features in the production of CMM, on-line near infrared spectroscopy (NIR) is used as an evaluating technology with its rapid, non-destructive and non-pollution etc. advantages. With the research in institutions, the on-line NIR applied in process analysis and control of CMM was described systematically, and the on-line NIR platform building was used as an example to clarify the feasibility of on-line NIR technology in CMM manufacturing process. Then, from the point of application by pharmaceutical companies, the current on-line NIR research on CMM and its production in pharmaceutical companies was relatively comprehensively summarized. Meanwhile, the types of CMM productions were classified in accordance with two formulations (liquid and solid dosage formulations). The different production processes (extraction, concentration and alcohol precipitation, etc. ) were used as liquid formulation diacritical points; the different types (tablets, capsules and plasters, etc.) were used as solid dosage formulation diacritical points, and the reliability of on-line NIR used in the whole process in CMM production was proved in according to the summary of literatures in recent 10 years, which could support the modernization of CMM production.

  14. A comparative evaluation of ProRoot mineral trioxide aggregate and Portland cement as a pulpotomy medicament.

    Science.gov (United States)

    Bhagat, Dipti; Sunder, Ravi Kadur; Devendrappa, Shashikiran Nandihalli; Vanka, Amit; Choudaha, Nidhi

    2016-01-01

    Recently, some studies have compared mineral trioxide aggregate (MTA) with portland cement (PC), concluding that the principle ingredients of PC are similar to those of MTA. The purpose of the present study was to evaluate the biocompatibility of PC as a pulpotomy medicament. Thirty premolars that scheduled for extraction for therapeutic reasons were randomly assigned to two experimental groups: ProRoot MTA (PMTA) and PC. After isolation and pulp exposure, pulpotomy was carried out and pulps were dressed with PMTA and PC. After 6 months, the teeth were extracted and prepared for histological analysis based on Cox et al. criteria. The data were analyzed by Z-test of proportion with 1% of allowed error. No statistically significant difference was found between the two groups with respect to inflammatory response, soft tissue organization, and dentine bridge formation (P > 0.05). PC was associated with similar favorable biological response to pulpotomy treatment as PMTA. The findings of this study support the idea that PC can be considered a cheaper substitute to MTA.

  15. Distinguishing the Chinese materia medica Tiepishihu from similar Dendrobium species of the same genus using histological and microscopic method.

    Science.gov (United States)

    Yu, Kun-Zi; Yan, Hua; Tai, Hai-Chuan; Zhang, Nan-Ping; Cheng, Xian-Long; Guo, Zeng-Xi; Ma, Shuang-Cheng; Wei, Feng

    2017-07-01

    The Chinese Materia Medica, Tiepishihu, used as a tonic for over one thousand years, is a well-known precious medicine in China. According to the Chinese Pharmacopoeia, its source is the species Dendrobium officinale Kimura et Migo, which is distinguished from other species in Dendrobium genus. However, these species from the same genus are similar with Tiepishihu and caused confusion in the market. To find a quick and simple method to distinguish Tiepishihu from other similar species, histologic and microscopic methods were combined together to investigate the transverse section of stem of Tiepishihu and other similar species. Phloroglucinol test solution with hydrochloric acid was used to reveal the lignified tissue by staining the transverse section of Tiepishihu and similar species. Results revealed the unique identification characteristics to distinguish Tiepishihu from similar species, which were difficult to distinguish by other methods. The identification characteristics of Tiepishihu include the cells of vascular bundle sheath were stained red, parenchyma cells were not stained red. What's more, other species can be distinguished from each other with microscopic and histological characteristics. These characteristics proved stable and can be easily observed by normal light microscopic examination. This method is rapid, accurate, stable, and inexpensive. © 2017 Wiley Periodicals, Inc.

  16. Presentation of the DosePet application (APP) for use in Nuclear Medicine: calculation of the amount of medicament for PET / CT patients

    International Nuclear Information System (INIS)

    Nascimento, Pedro Augusto do; Rodrigues, Araken dos S. Werneck

    2016-01-01

    This paper presents the application (APP) DosePet that calculates the amount of medicament for PET / CT in patients according to the predetermined radiation dose. The software has been designed using the web MIT App Inventor2 tool for Android platform. The application allows the workers to simulate the amount of radiation still existing in the premises after the applications, increasing security and reducing exposures, and enable greater efficiency in the use of the radiopharmaceutical. (author)

  17. Aux frontières du politique et du religieux

    Directory of Open Access Journals (Sweden)

    Frédéric Sylvanise

    2006-05-01

    Full Text Available The Autobiography of Miss Jane Pittman met en scène de manière spectaculaire deux figures de leadership noir-américain au XIXe siècle (Ned et au XXe siècle (Jimmy. Ned, fils adoptif de Jane Pittman, se rebaptise Professor Douglass en hommage au leader abolitionniste Frederick Douglass. S’il est fondamentalement laïc (il est instituteur, le texte lui confère néanmoins une dimension religieuse, notamment dans le chapitre intitulé « The Sermon at the River » , qui renvoie à la fois à Moïse (le fleuve et à Jésus (le sermon sur la montagne. Abattu par un tueur à gages, Ned est un martyr dont l’histoire était déjà écrite. Le personnage de Jimmy, attendu par toute une communauté comme le messie (alors que lui aussi est un laïc et un homme qui perd la foi, s’inscrit dans la même histoire. Lettré, éloquent et impliqué dans le mouvement pour les droits civils, il est assassiné comme son prédécesseur. Dans les deux cas, le texte lie donc le politique et le biblique comme s’il ne faisait qu’un : être un leader politique, c’est être un preacher et un messie qui guide le peuple. Il est possible de lire l’évocation de ces deux hommes à la lumière d’une certaine actualité. Ned et Jimmy connaissent en effet un sort proche de celui de Malcolm X et de Martin Luther King, récemment assassinés au moment de l’écriture de The Autobiography of Miss Jane Pittman. C’est l’histoire de la répression du leadership noir, au travers du portrait de deux de ses avatars, qui peut donc se lire en creux ici.

  18. Complications du traitement traditionnel des fractures : aspects ...

    African Journals Online (AJOL)

    Tous les patients reçus avec des complications du traitement traditionnel des fractures ont été inclus dans ce travail. Le diagnostic des lésions était clinique et radiologique. Nous avions reçu 51 patients porteurs de complications suite à des traitements de médecine traditionnelle, soit 13,7% du total des patients hospitalisés ...

  19. Le désordre du monde

    African Journals Online (AJOL)

    sulaiman.adebowale

    Le début du XXIe siècle se caractérise par l'accumulation et la consécution ..... Unis a présidé à la naissance aux forceps de cet outil d'équilibre du monde en ... De toute évidence, l'ONU reste l'instrument qui a marqué le siècle dernier,.

  20. Effect of calcium hydroxide and triple antibiotic paste as intracanal medicaments on the incidence of inter-appointment flare-up in diabetic patients: An in vivo study

    Science.gov (United States)

    Pai, Swathi; Vivekananda Pai, A. R.; Thomas, Manuel S.; Bhat, Vishal

    2014-01-01

    Aim: To evaluate and compare the effect of antibacterial intracanal medicaments on inter-appointment flare-up in diabetic patients. Materials and Methods: Fifty diabetic patients requiring root canal treatment were assigned into groups I, II, and III. In group I, no intracanal medicament was placed. In groups II and III, calcium hydroxide and triple antibiotic pastes were placed as intracanal medicaments, respectively. Patients were instructed to record their pain on days 1, 2, 3, 7, and 14. Inter-appointment flare-up was evaluated using verbal rating scale (VRS). Results: Overall incidence of inter-appointment flare-up among diabetic patients was found to be 16%. In group I, 50% of the patients and in group II, 15% of the patients developed inter-appointment flare-up. However, no patients in group III developed inter-appointment flare-up. The comparison of these results was found to be statistically significant (P = 0.002; χ2 = 12.426). However, with respect to intergroup comparison, only the difference between groups I and III was found to be statistically significant (P = 0.002; χ2 = 12.00). Conclusions: Calcium hydroxide and triple antibiotic paste are effective for managing inter-appointment flare-ups in diabetic patients. Triple antibiotic paste is more effective than calcium hydroxide in preventing the occurrence of flare-up in diabetic patients. PMID:24944440

  1. Pru du 2S albumin or Pru du vicilin?

    Science.gov (United States)

    Garino, Cristiano; De Paolis, Angelo; Coïsson, Jean Daniel; Arlorio, Marco

    2015-06-01

    A short partial sequence of 28 amino acids is all the information we have so far about the putative allergen 2S albumin from almond. The aim of this work was to analyze this information using mainly bioinformatics tools, in order to verify its rightness. Based on the results reported in the paper describing this allergen from almond, we analyzed the original data of amino acids sequencing through available software. The degree of homology of the almond 12kDa protein with any other known 2S albumin appears to be much lower than the one reported in the paper that firstly described it. In a publicly available cDNA library we discovered an expressed sequence tag which translation generates a protein that perfectly matches both of the sequencing outputs described in the same paper. A further analysis indicated that the latter protein seems to belong to the vicilin superfamily rather than to the prolamin one. The fact that also vicilins are seed storage proteins known to be highly allergenic would explain the IgE reactivity originally observed. Based on our observations we suggest that the IgE reactive 12kDa protein from almond currently known as Pru du 2S albumin is in reality the cleaved N-terminal region of a 7S vicilin like protein. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Les effets du changement climatique dans le bassin du Congo : la ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    22 avr. 2016 ... Dans le bassin du fleuve Congo, plus de 80 % des habitants vivent exclusivement de l'agriculture, de la pêche, de l'élevage et de la cueillette, qui sont des activités largement tributaires du climat.

  3. Engagez-vous, devenez délégué(e) du personnel du CERN

    CERN Multimedia

    Staff Association

    2017-01-01

    Dans notre ECHO N° 275, nous avons annoncé les élections à venir au Conseil du personnel du CERN. Dans le présent ECHO, nous vous informons du lancement du processus des élections qui débute par le dépôt des candidatures. Tous les titulaires, boursiers et associés, qui sont aussi membres de l’Association du personnel, peuvent s’engager et déposer leur candidature entre le 11 septembre à 08 h 00 et le 13 octobre 2017 à 17 h 00. N’hésitez plus, remplissez le formulaire de candidature, présentez-vous aux élections au Conseil du personnel afin de pouvoir représenter et défendre vos collègues du personnel du CERN. ÊTRE DÉLÉGUÉ(E), C’EST QUOI ? Poser la question à plusieurs d...

  4. Aux marges du monde arabe

    Directory of Open Access Journals (Sweden)

    Hélène Thiollet

    2004-09-01

    Full Text Available L’étude des migrations contemporaines des Érythréens vers le Yémen au tournant des années quatre-vingt-dix permet d’observer les transformations des dynamiques régionales à l’œuvre dans le monde arabe. Les migrations sont un phénomène sensible aux différents aspects (politiques, économiques, culturels, géographiques de l’intégration régionale. Celle si est envisagée dans cet article à travers une approche doublement marginale : -la marginalité géographique de l’Érythrée arabo-africaine et du Yémen, économi­quement isolé dans la péninsule Arabique, -l’étude des migrations formelles et informelles, élément souvent marginal dans l’étude des institutions et des échanges qui constituent un système régional intégré. Cette étude est fondée sur une série d’entretiens menés au Yémen entre février et avril 2002 auprès des administrations yéménites et de la population érythréenne.

  5. Cirque du Monde as a health intervention

    Science.gov (United States)

    Fournier, Cynthia; Drouin, Mélodie-Anne; Marcoux, Jérémie; Garel, Patricia; Bochud, Emmanuel; Théberge, Julie; Aubertin, Patrice; Favreau, Gil; Fleet, Richard

    2014-01-01

    Abstract Objective To present Cirque du Soleil’s social circus program, Cirque du Monde, to explore its potential as a primary health care tool for family physicians. Data sources A review of the literature in PubMed, the Cochrane Library, PsycINFO, LaPresse, Eureka, Google Scholar, and Érudit using the key words circus, social circus, Cirque du Monde, and Cirque du Soleil; a Montreal-based initiative, Espace Transition, modeled on Cirque du Monde; and personal communication with Cirque du Soleil’s Social Circus Training Advisor. Study selection The first 50 articles or websites identified for each key word in each of the databases were examined on the basis of their titles and abstracts in the case of articles, and on the basis of their titles and page content in the case of websites. Articles and websites that explored an aspect of social circuses or that described an intervention that involved circuses were then retained for analysis. Because all literature on social circuses was searched, no criterion for year of publication was used. Synthesis No articles on the social circus as a health intervention were found. One study on the use of the circus as an intervention in schools was identified. It demonstrated an increase in self-esteem in the children who took part. One study on the use of the circus in a First Nations community was found; it contained nonspecific, qualitative findings. The other articles identified were merely descriptions of social circuses. One website was identified on the use of the social circus to help youth who had been treated in a hospital setting for major psychiatric disorders to re-enter the community. The team in the pediatric psychiatry department at Centre Hospitalier Universitaire Sainte-Justine, the children’s hospital in Montreal, Que, was contacted; they were leading this project, called Espace Transition. The unpublished preliminary findings of its pilot project demonstrate substantial improvements in overall patient

  6. The deep cerebral stimulation of the under thalamic nucleus modifies the cerebral metabolism in {sup 18}FDG-Tep of obsessive compulsive patients; La stimulation cerebrale profonde du noyau sous thalamique modifie le metabolisme cerebral en 18FDG-TEP des patients obsessionnels compulsifs

    Energy Technology Data Exchange (ETDEWEB)

    Le Jeune, F.; Garin, E. [Service de medecine nucleaire, centre Eugene-Marquis, Rennes, (France); Verin, M.; Peron, J. [service de neurologie, CHU Pontchaillou, Rennes, (France); Mallet, L.; Yelnik, J. [Inserm, Avenir Team, Behavior, Emotion and Basal Ganglia, IFR 70, Pitie-Salpetriere, Paris, (France); Kreps, M.O. [Inserm U796, service de psychiatrie, hopital Sainte-Anne, Paris, (France); Drapier, D.; Millet, B. [service de psychiatrie adulte, centre hospitalier Guillaume-Regnier, Rennes, (France)

    2009-05-15

    The aim of this work was to find again this orbito-frontal hyper metabolism among the resistant obsessive compulsive disorder patients that are going to benefit of a deep cerebral stimulation of the under thalamus nucleus and to demonstrate that this new therapy approach leads a reduction of the metabolism in this area in correlation with the clinical improvement. It is about the first study realized in isotopic functional imaging on ten resistant compulsive disorder patients treated by bilateral deep cerebral stimulation of the under thalamus nucleus. It shows that the treatment efficiency is in relation with a reduction of the glucide metabolism in the right orbito-frontal cortex. It suggests equally that the under thalamus nucleus would be functionally linked to the orbito-frontal cortex. (N.C.)

  7. Is a 50 Hz magnetic field susceptible to change the iron metabolism and to induce an anemia?; Un champ magnetique de 50 Hz est-il susceptible d'alterer le metabolisme du fer et d'induire une anemie?

    Energy Technology Data Exchange (ETDEWEB)

    Nafziger, J. [Universite Rene Descartes, Lab. d' Hematologie Cellulaire et Moleculaire, UPRES EA-2509, UFR des Sciences Pharmaceutiques et Biologiques de Paris, 75 - Paris (France)

    2001-07-01

    Significant difference have been observed between the exposed and the reference persons for the iron by storage in the spleen and for the percentage of red line cells in the bone marrow, but the observed changes have not been associated to an anemia during the fifteen exposure weeks. however, given the change in iron storage and the reduction of red line cells in the bone marrow, the possibility of delayed effects is not out of the question. (N.C.)

  8. Établissements recevant du public

    CERN Document Server

    2014-01-01

    Synthèse pour les installations électriques, des règles de sécurité contre les risques d’incendie et de panique dans les établissements recevant du public (ERP), selon l’arrêté du 25 juin 1980 modifié. L'ouvrage traite à la fois des dispositions communes aux établissements du 1er groupe (1ère à 4ème catégorie), du 2ème groupe (5ème catégorie) et des règles particulières applicables aux différents types d'établissements (structures d'accueil pour personnes âgées ou handicapées, hôtels, magasins de vente, restaurants et débit de boisson, établissements de soins, administration, châpiteaux, etc...) Sont ainsi notamment traités, dans le cadre des dispositions communes aux établissements du 1er groupe, pour les installations électriques normales : les installations des appareils, tableaux et canalisations, les locaux électriques et installation de machines, l'éclairage normal des locaux accessibles au public, le chauffage et la ventilation, l'installation d'eau chaude sanita...

  9. Sådan kan du bruge optioner og futures

    DEFF Research Database (Denmark)

    Kohl, Niklas

    2017-01-01

    Masterclass. Har du brug for at forsikre værdierne i din portefølje i en periode, hvor du forventer stor uro på finansmarkederne, kan du gøre det med optioner eller futures. Her kan du læse om de forskellige typer – og om de muligheder de giver dig.......Masterclass. Har du brug for at forsikre værdierne i din portefølje i en periode, hvor du forventer stor uro på finansmarkederne, kan du gøre det med optioner eller futures. Her kan du læse om de forskellige typer – og om de muligheder de giver dig....

  10. Science et technologie du collage

    CERN Document Server

    Cognard, Jacques

    2003-01-01

    L'Homme a su coller avant de savoir écrire et compter. Le collage est en effet l'une des premières techniques d'assemblage d'une structure que l'homme ait utilisée, technique qui n'est devenue science qu'au début du 20e siècle avec la fabrication des premières colles synthétiques. Cette science de l'adhésion a considérablement progressé ces dix dernières années et ce livre présente l'état actuel des connaissances en décrivant les progrès considérables réalisés dans la compréhension des phénomènes fondamentaux qui font qu'un collage tient bien et durablement. Après l'exposé des bases scientifiques nécessaires et des modèles théoriques récents, l'auteur introduit la distinction entre collages faibles et collages forts puis expose les difficultés rencontrées dans les cas pratiques, difficultés souvent dues à la complexité de la chimie des surfaces et des réactions surface-polymère. L'ouvrage se termine par la présentation de quelques applications récentes, en particulier dans...

  11. Accroissement du recours aux politiques fiscales dans la lutte ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Incidence de la hausse des taxes sur le tabac et du prix des produits du tabac en Ukraine, en Russie et au Bélarus. La recherche destinée aux responsables des politiques de l'Ukraine, de la Russie et du Bélarus mettra en évidence la façon dont les mesures de taxation des produits du tabac peuvent contribuer.

  12. Couzeix – Les Terres du Puy Dieu

    OpenAIRE

    Maniquet, Christophe

    2013-01-01

    Identifiant de l'opération archéologique : 122281 Date de l'opération : 2005 (EX) Dans le cadre du projet de construction d'un lotissement constitué de trois pavillons au lieu-dit « Les Terres du Puy Dieu », un diagnostic archéologique a été prescrit par le service régional de l'Archéologie. En effet, plusieurs sites archéologiques avaient été inventoriés à proximité immédiate de la zone d'intervention. On notera, en particulier, la découverte en 1982, près du Puy Dieu, au cours de travaux de...

  13. Profils des porteurs du VIH/SIDA au début du traitement ...

    African Journals Online (AJOL)

    But : Décrire les profils des porteurs de VIH/sida au début du traitement antirétroviral. Matériels et méthode: Les dossiers des porteurs du VIH/sida de la région maritime ont été analysés de mai 2008 à avril 2009 par le comité thérapeutique. Résultats: Parmi les 641 dossiers analysés, 67,40% venaient du district de Yoto.

  14. Distribution spatiale du singe à ventre rouge, Cercopithecus ...

    African Journals Online (AJOL)

    danger et endémique du Dahomey Gap est très peu documenté au Togo. Pour connaître sa ..... chaque secteur prospecté ainsi que celui du complexe en entier. ..... 2008-009 portant loi-cadre sur l'environnement au Togo. JO du 06 juin. 2008.

  15. Directeur, Gestion du risque et audit interne | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Résumé des fonctions En qualité de dirigeant principal de l'audit (DPA), ... président du Centre et au président du Comité des finances et de l'audit une assurance et des ... Il fournit des services de gestion du risque organisationnel et d'autres ...

  16. Webzzle : paradoxal confort du confinement.

    Directory of Open Access Journals (Sweden)

    Marc Dumont

    2007-06-01

    Full Text Available La plupart des agences de « news » technologiques viennent de se faire l’écho du développement de Webzzle , un nouveau moteur de recherche dit « collaboratif ». Ce cas est tout à fait intéressant parce qu’il permet de pointer rapidement quelques grands enjeux du Web 2 que risquent souvent de dissimuler la jungle sémantique et l’enthousiasme qui l’entourent. Pour quelles raisons ? Rappelons d’abord les deux principales perspectives ouvertes par cette nouvelle ...

  17. Krypton purification (1961); Purification du krypton (1961)

    Energy Technology Data Exchange (ETDEWEB)

    Larher, Y [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires; Institut Fourier, 38 - Grenoble (France)

    1961-07-01

    The amount of xenon in otherwise very pure krypton can be reduced from 1.5 to 0.0025 per cent approximately by passage through an activated carbon column at dry-ice temperature. The circulation of the krypton is effected by condensing at -196 deg. C and then evaporating. (author) [French] Le taux de xenon dans du krypton par ailleurs tres pur est ramene de 1,5 pour cent a 0,0025 pour cent environ au cours d'un passage a travers une colonne de charbon actif a la temperature de la carboglace. La circulation du krypton se fait par condensation a -196 deg. C, puis evaporation. (auteur)

  18. Funcionamento intelectual em pacientes pediátricos com epilepsia: comparação de crianças controladas com medicação, não controladas com medicação e controladas com cirurgia

    OpenAIRE

    Souza-Oliveira,Cecília; Escosi-Rosset,Sara; Funayama,Sandra S.; Terra,Vera C.; Machado,Hélio R.; Sakamoto,Américo C.

    2010-01-01

    OBJETIVO: Comparar o quociente intelectual (QI) em três grupos de crianças com epilepsia: 1) controlados com medicação, 2) não controlados com medicação e 3) controlados com cirurgia. MÉTODOS: Noventa e oito pacientes pediátricos, com idades entre 6 e 12 anos, foram selecionados de dezembro de 2007 a julho de 2008. A Escala de Inteligência Wechsler para Crianças - terceira edição (WISC-III) foi utilizada para a avaliação neuropsicológica dos pacientes. Os resultados foram relacionados com a s...

  19. Effets de la microdose sur la production du niébé, du mil et du ...

    African Journals Online (AJOL)

    respectivement pour le sorgho, le mil et le niébé comparativement au témoin. La microdose a été .... Les prix utilisés sont celui du marché local au moment des semis pour les engrais soit 17500 FCFA pour NPK et ..... Projet « Transfert de la.

  20. Lupus induced by medicaments

    International Nuclear Information System (INIS)

    Canas D, Carlos Alberto; Perafan B, Pablo Eduardo

    2001-01-01

    We describe a 55 years old female patient who consulted by fever syndrome, artralgias and the presence of high tittles positives antinuclear antibodies. She had arterial hypertension in treatment with captopril. We suspected the clinical diagnoses of drug-induced lupus; the withdraw of captopril was associated with the remission of the clinical and laboratory manifestations

  1. L’ombre du Condor

    Directory of Open Access Journals (Sweden)

    Franck Gaudichaud

    2003-09-01

    Full Text Available Si l’on observe aujourd’hui, avec un regard d’historien, le Cône Sud à la fin des années soixante soixante-dix et que par, la suite, on tourne une page de quelques années, pour fixer la même partie du monde, le constat est sans appel : le sous-continent latino-américain est passé, en général, d’une phase de forte mobilisation et politisation sociale, montée en puissance de partis et organisations révolutionnaires, surgissements de gouvernements populistes de gauche ou progressistes – appelant à une rupture avec l’impérialisme –, à un reflux généralisé du mouvement ouvrier, une ère de violence politique étatisée, la destruction massive de tous les espaces d’expression et de participation démocratiques, l’écrasement physique et idéologique sans relâche des militants et mouvements révolutionnaires, la mise en place de modèles économiques capitalistes dirigistes puis/ou néolibéraux. Que s’est-il passé ? Quel fil conducteur a été rompu et par quels moyens l’Amérique Latine a été conduite à ce reflux des luttes sociales ? Pour répondre à cette question, nous nous contenterons dans cet article de focaliser notre objectif sur un aspect spécifique et essentiel de ce retournement de tendance que vit alors l���Amérique Latine : celui de la mise en place d’un terrorisme d’Etat contre-révolutionnaire transnational, appuyé par l’impérialisme américain, nommé « l’Opération Condor ». Dans cet article, il s’agit de montrer le fonctionnement d’un terrorisme hégémonique dont l’impact sur les sociétés latino-américaines est considérable en termes de destruction du mouvement social, des activités culturelles et de l’ensemble de la vie sociale et politique qui restent marquées, encore aujourd’hui à des degrés divers, par la violence, la peur et l’atomisation structurelle.Si miramos hoy en día, desde una perspectiva histórica, el Cono Sur hacia finales de

  2. UHPLC/Q-TOFMS-based metabolomics for the characterization of cold and hot properties of Chinese materia medica.

    Science.gov (United States)

    Wang, Yang; Zhou, Shujun; Wang, Meng; Liu, Shuying; Hu, Yuanjia; He, Chengwei; Li, Peng; Wan, Jian-Bo

    2016-02-17

    The cold/hot property of Chinese materia medica (CMM) and the application of its corresponding knowledge in the diagnosis, differentiation and treatment of diseases have been considered to be the extremely important part of traditional Chinese medicine (TCM). As highly abstracted TCM theory, the cold/hot property of CMMs is still not fully understood and remains to be elucidated by systems biology approach. The cold and hot properties of CMM are mainly defined by the response of the body to a given CMM. Metabolomics is a promising systems biology method to profile entire endogenous metabolites and monitor their fluctuations related to an exogenous stimulus. Thus, a metabolomics approach was applied to characterize the cold and hot properties of CMMs. Mice were intragastrically administered three selected cold property CMMs (i.e., Rheum palmatum L., radix et rhizoma; Coptis chinensis Franch, rhizome and Scutellaria baicalensis Georgi, radix) and three hot property CMMs (i.e., Cinnamomum cassia (L.) J. Presl, cortex; Zingiber officinale Roscoe, rhizoma and Evodia rutaecarpa (Juss.) Benth., fructus) once daily for one week. The comprehensive metabolome changes in the plasma of mice after treatment with cold or hot property CMMs were characterized by ultra-high performance liquid chromatography/time of flight mass spectrometry (UHPLC/Q-TOF-MS), and the potential biomarkers related to cold and hot properties of CMM were explored. Metabolites perturbation in plasma occurs after treatment with cold CMMs and hot CMMs in mice, and 15 and 16 differential biomarkers were identified to be associated with the cold and hot properties of CMMs, respectively. Among them, LPC (18:0), LPC (18:1), LPC (20:4) and LPC (20:5) showed decreased trends in the cold property CMM treated groups, but increased in the hot property CMM treated groups. There is a strong connection between the cold/hot property of CMMs and lysophosphatidylcholines metabolism. This study offers new insight

  3. [Methodological quality and reporting quality evaluation of randomized controlled trials published in China Journal of Chinese Materia Medica].

    Science.gov (United States)

    Yu, Dan-Dan; Xie, Yan-Ming; Liao, Xing; Zhi, Ying-Jie; Jiang, Jun-Jie; Chen, Wei

    2018-02-01

    To evaluate the methodological quality and reporting quality of randomized controlled trials(RCTs) published in China Journal of Chinese Materia Medica, we searched CNKI and China Journal of Chinese Materia webpage to collect RCTs since the establishment of the magazine. The Cochrane risk of bias assessment tool was used to evaluate the methodological quality of RCTs. The CONSORT 2010 list was adopted as reporting quality evaluating tool. Finally, 184 RCTs were included and evaluated methodologically, of which 97 RCTs were evaluated with reporting quality. For the methodological evaluating, 62 trials(33.70%) reported the random sequence generation; 9(4.89%) trials reported the allocation concealment; 25(13.59%) trials adopted the method of blinding; 30(16.30%) trials reported the number of patients withdrawing, dropping out and those lost to follow-up;2 trials (1.09%) reported trial registration and none of the trial reported the trial protocol; only 8(4.35%) trials reported the sample size estimation in details. For reporting quality appraising, 3 reporting items of 25 items were evaluated with high-quality,including: abstract, participants qualified criteria, and statistical methods; 4 reporting items with medium-quality, including purpose, intervention, random sequence method, and data collection of sites and locations; 9 items with low-quality reporting items including title, backgrounds, random sequence types, allocation concealment, blindness, recruitment of subjects, baseline data, harms, and funding;the rest of items were of extremely low quality(the compliance rate of reporting item<10%). On the whole, the methodological and reporting quality of RCTs published in the magazine are generally low. Further improvement in both methodological and reporting quality for RCTs of traditional Chinese medicine are warranted. It is recommended that the international standards and procedures for RCT design should be strictly followed to conduct high-quality trials

  4. Étude de la qualité des eaux usées des deux retenues du bassin du ...

    African Journals Online (AJOL)

    SARAH

    31 mai 2017 ... Gourou au carrefour de l'Indénié à Abidjan en 2012. 11138. Journal of Applied .... retenues sont nées du projet de gestion intégrée du bassin du Gourou (CI-FAD, ..... Contrôle de la qualité microbiologique des eaux usées ...

  5. 26 Calcul multi-caractéristique du coût du non-qualité via la fonction ...

    African Journals Online (AJOL)

    PR BOKO

    Le coût du non - qualité (CNQ) est un indicateur permettant l'estimation de la marge ..... multicritères de Taguchi en fonction de l'évolution du poids et capacité du ... A Scheduling Example; International Journal of Information and Management.

  6. Le Flaubert de Charles Du Bos

    Directory of Open Access Journals (Sweden)

    Jacques Neefs

    2009-01-01

    Full Text Available Charles Du Bos a porté une attention constante à l’œuvre de Flaubert (à l’exclusion de Bouvard et Pécuchet qui semble ne pas exister pour lui, à Madame Bovary et à L’Éducation sentimentale en particulier. La mise en relation de son étude : « Sur le milieu intérieur chez Flaubert », écrite en 1921, avec des textes du Journal de 1923 et de 1937, les rapprochements avec Gogol, Thomas Hardy, Tolstoï, Baudelaire, Henry James qui traversent les écrits de Du Bos, permettent de suivre ce que celui-ci décrit comme « l’expérience spirituelle » d’une matérialité comprise dans la conquête de la triple exigence du Beau, du Vivant et du Vrai. Du Bos décèle la force de l’œuvre de Flaubert dans la « disproportion » du style, et dans la puissance d’absorption qui fait la densité de cette prose, et qui désigne un extraordinaire travail de conversion. L’obscure expérience spirituelle ainsi poursuivie est celle d’un absolu de l’art, expérience paradoxale d’un « mystique qui ne croit à rien » (comme se désignait Flaubert lui-même, que le critique lie à une interrogation sur sa propre conversion.Charles Du Bos devoted an unflagging attention to Flaubert’s work (except for Bouvard et Pécuchet, which, apparently, according to him did not exist, to Madame Bovary and in particular L’Éducation sentimentale. The connection between his essay “Sur le milieu intérieur chez Flaubert”, written in 1921, and extracts from his Journal, from 1923 to 1937, the comparisons with Gogol, Thomas Hardy, Tolstoy, Baudelaire, and Henry James that run through the writings of Du Bos, allow us to follow what he terms “the spiritual experience” of a materiality encompassed in the conquest of the triple demand of the Beautiful, the Living, the Truth. Du Bos detects the power of Flaubert’s work in the “disproportion” of his style, and the power of absorption that forms the density of his prose, showing an

  7. Alternativas de medicação intracanal em casos de necrose pulpar com lesão periapical = Intracanal medication indicated for pulpal necrosis with apical osteites

    OpenAIRE

    Fachin, Elaine Vianna Freitas

    2006-01-01

    Trata-se de estudo in vivo em pacientes portadores de dentes monorradiculares apresentando necrose pulpar com lesão periapical. O objetivo foi avaliar radiograficamente a efetividade de 4 diferentes curativos de demora (PMCC, gel de clorexidina 2%, pasta de hidróxido de cálcio e hipoclorito de sódio1%). O tratamento endodôntico foi padronizado em todos os elementos através da técnica escalonada e irrigação com hipoclorito de sódio 1%. Para a medicação intracanal, os pacientes foram separados ...

  8. Analyses de la dégradation du lac Kinkony pour la conservation du ...

    African Journals Online (AJOL)

    Le lac Kinkony fait partie des habitats clefs pour la biodiversité du Complexe des ... provide favoured habitat for numerous endemic and endangered avian, fish ... on fauna is essential for developing regional conservation and natural resource ...

  9. Consolidation du leadership en recherche en écosanté en Asie du ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    1 juin 2016 ... Financée par le CRDI, l'Initiative de renforcement du leadership en recherche en écosanté en Asie du Sud‑Est appuie l'exécution, dans la région, de travaux de recherche qui visent à permettre de mieux comprendre les effets de la transformation de l'agriculture sur les écosystèmes et sur la santé humaine ...

  10. Accroissement de la compétitivité du Kenya dans l'économie du ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    La promulgation par le Kenya du Science, Technology and Innovation Bill, 2012 confirme l'intérêt et la volonté du gouvernement de mettre en oeuvre désormais un programme de développement fondé sur la science. La loi offre aussi au CRDI l'occasion d'appuyer le programme de recherche et de politiques de la nouvelle ...

  11. Effets du travail du sol sur le comportement chimique et biologique ...

    African Journals Online (AJOL)

    SARAH

    31 juil. 2017 ... RESUME. Objectif : L'objectif de cette étude est de comparer les effets de six techniques culturales de mise en place du blé tendre sur certaines propriétés chimiques et biologiques du sol et les conséquences sur le rendement grain et ses composantes dans la région «non chernozem» en 7ème années ...

  12. OGM : vers une définition commune du contenu du problème ?

    Directory of Open Access Journals (Sweden)

    Icart Jean-Claude

    2001-07-01

    Full Text Available Les divergences croissantes depuis des années entre experts, responsables économiques, et acteurs sociaux et « citoyens » au sujet des OGM, ont pu être analysées à juste titre, comme exprimant la difficulté de dégager une « définition commune du contenu du problème »1.

  13. Évaluation du nouveau programme d'études du College of Health ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Ces changements étaient jugés nécessaires pour préparer les professionnels de la santé aux nouvelles exigences de la prestation de services de santé décentralisés, pour juguler les nouvelles pandémies comme celles du VIH/sida et du virus Ébola, ainsi que pour répondre aux besoins des malades dans les zones ...

  14. Une force venant du futur chercherait à saboter l'expérience du LHC...

    CERN Multimedia

    Scappaticci, Bruno

    2009-01-01

    "A quelques jours de la reprise de l'expérience du LHC, on ne parle plus de la menace d'un trou noir, mais deux physicines souteinnent aujourd'hui une tout autres hypothèse: la nature, depuis le futur, va continuer de contrarier les travaux du Cern, afin d'éviter à l'Homme de mettre le doigt là où il ne faut pas..." (1.5 pages)

  15. Cartes infographiques du Symposium Afrique de l'Ouest et du Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    fdieudonne

    VILLES SÛRES ET INCLUSIVES | AFRIQUE DE L'OUEST ET DU CENTRE. Spécificités de violence, d'exclusion, et de lutte contre la criminalité. République démocratique du Congo: Taux de natalité par femme, en moyenne 10 enfants, très élevé. Exclusion sociale exacerbée : des jeunes enfants accusés de sorcellerie.

  16. Une mesure différente du bien-être : l'indice du bonheur national ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    À la lumière de ces données, le Centre for Bhutan Studies publiera, en 2011, un indice du BNB quantitatif. Cette subvention permettra à l'OPHI d'assister le Centre dans la synthèse et l'analyse des résultats de l'enquête de 2010. L'objectif : assurer la validité et la reconnaissance internationale de l'indice du BNB de sorte ...

  17. Maison du Peuple; Jean Prouvè

    DEFF Research Database (Denmark)

    Beim, Anne

    2017-01-01

    The chapter presents a deep analysis of Maison du Peuple, de Clichy in Paris by the French architect and manufacturer Jean Prouvè. The historical context of the original ideas behind the building and how and by which means it was constructed are being examined from a tectonic perspective....

  18. les cahiers du cread - Vol 101 (2012)

    African Journals Online (AJOL)

    Les importations subventionnees de genisses a haut potentiel laitier : Un echec du a l'absence de politique laitiere globale · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Hamida Kheffache, Slimane Bedrani ...

  19. The case of Cirque du Soleil Dralion

    African Journals Online (AJOL)

    Cirque entered this landscape not by competing with the traditional circus, but by redefining it altogether (Leslie ... Amidst the decline in traditional travelling circuses in South Africa, the popularity of sold-out Cirque du Soleil ... about their motives in order to devise effective marketing strategies. Swanson, Davis and Zhao ...

  20. Picholine marocaine clones X Picholine du Languedoc

    African Journals Online (AJOL)

    SERVER

    2007-12-17

    Dec 17, 2007 ... marocaine" cultivar and the "Picholine du Languedoc" cultivar, the descendants and their parents were analysed using 35 ... marocaine" is the most dominant cultivar; more than 98% ... this proportion, a χ2 test was calculated to test the null hypothesis. ... a lethal or semi-lethal locus (Bradshaw and Stettler,.

  1. récolte du melon

    African Journals Online (AJOL)

    SARAH

    30 sept. 2015 ... In vivo, 600 ppm of calcium silicate, calcium hydroxide and calcium oxide inhibited ... En 2013, la production du melon au Maroc a été .... Ca(OH)2, l'oxyde de calcium CaO, le sulfate de calcium ...... rot disease complex.

  2. PREDICTION DE LA CROISSANCE DU BANANIER PLANTAIN ...

    African Journals Online (AJOL)

    Hornik K., Stinchcombe M., White H., Auer P. 1994. Degree of approximation results of feedforward networks approximating unknown mapping et their derivatives. Neur. Net. Comp., 6 : 1262 - 1275. Jannoyer M. 1995. Déterminisme du nombre d'or- ganes reproducteurs d'une inflorescence de bananier (Musa acuminata, ...

  3. Etude de la transition ferroelectrique-ferroelastique du KD2PO4 forme du front de phase en fonction du gradient thermique

    OpenAIRE

    Kvítek, Zdeněk

    2010-01-01

    Etude de la transition ferroelectrique-ferroelastique du KD2PO4 forme du front de phase en fonction du gradient thermique The thesis explores complex process of first order transition of KD2PO4 crystal from tetragonal phase to ferroelectric - ferroelastic orthorhombic phase and back at temperature 209 K. The experimental set up of nitrogeneous cryostat allowes temperature and temperature gradient variations during simultaneous three axes optical sample observations, dielectric measurements. T...

  4. Néotoponymie contestée à Potchefstroom / Tlokwe (Province du Nord-Ouest, Afrique du Sud

    Directory of Open Access Journals (Sweden)

    Myriam Houssay-Holzschuch

    2010-09-01

    Full Text Available Illustration 1 - Extrait du site de la municipalité de Potchefstroom / TlokweSource : http://www.potch.co.za/newsarchive/streetnames.htmlIllustration 2- Potchefstroom (Afrique du SudAuteur : Béatrice Obry-Guyot, début décembre 2007.Illustration 3 - Extrait du plan Google Map de PotchefstroomSource : Google Map.La question toponymique en Afrique du Sud sur la longue durée porte sur deux thèmes essentiels porteurs de controverses : le plurilinguisme et le marquage symbolique et mémoriel du te...

  5. Sequential cloud-point extraction for toxicological screening analysis of medicaments in human plasma by high pressure liquid chromatography with diode array detector.

    Science.gov (United States)

    Madej, Katarzyna; Persona, Karolina; Wandas, Monika; Gomółka, Ewa

    2013-10-18

    A complex extraction system with the use of cloud-point extraction technique (CPE) was developed for sequential isolation of basic and acidic/neutral medicaments from human plasma/serum, screened by HPLC/DAD method. Eight model drugs (paracetamol, promazine, chlorpromazine, amitriptyline, salicyclic acid, opipramol, alprazolam and carbamazepine) were chosen for the study of optimal CPE conditions. The CPE technique consists in partition of an aqueous sample with addition of a surfactant into two phases: micelle-rich phase with the isolated compounds and water phase containing a surfactant below the critical micellar concentration, mainly under influence of temperature change. The proposed extraction system consists of two chief steps: isolation of basic compounds (from pH 12) and then isolation of acidic/neutral compounds (from pH 6) using surfactant Triton X-114 as the extraction medium. Extraction recovery varied from 25.2 to 107.9% with intra-day and inter-day precision (RSD %) ranged 0.88-1087 and 5.32-17.96, respectively. The limits of detection for the studied medicaments at λ 254nm corresponded to therapeutic or low toxic plasma concentration levels. Usefulness of the proposed CPE-HPLC/DAD method for toxicological drug screening was tested via its application to analysis of two serum samples taken from patients suspected of drug overdosing. Published by Elsevier B.V.

  6. Présentation du volume

    Directory of Open Access Journals (Sweden)

    Ana Zwitter Vitez

    2012-12-01

    Full Text Available Dans de nombreuses disciplines scientifiques, le discours parlé représente depuis quelques décennies un objet de recherche proéminent. Ce fait s’explique probablement par deux caractéristiques principales du discours parlé: la structure complexe de sa matérialité et les fonctions variées de différentes pratiques langagières. C’est pourquoi le présent numéro réunit les articles basés sur les approches actuelles du discours parlé et sur les pratiques langagières spécifiques. Le volume est introduit par deux articles interdisciplinaires: Peter Garrard et Ahmed Samrah présentent le domaine de la pathologie du langage en donnant une revue fouillée sur les approches actuelles de l’analyse linguistique lors de la détection de la maladie d’Alzheimer, tandis que Harry Hollien donne un aperçu structuré sur le domaine de la phonétique judiciaire destiné à dévoiler l’identité des locuteurs et de détecter la déception dans le discours parlé. Les analyses explorant l’acquisition du langage commencent par l’article de Katharina Zipser qui examine la progression de structures grammaticales en les mettant en comparaison avec la compétence des apprenants et continuent par l’étude de Meta Lah proposant une évaluation des documents audiovisuels proposés aux apprenants de langue étrangère. Vesna Požgaj Hadži, Damir Horga et Tatjana Balažic Bulc remettent en question la corrélation entre la compétence linguistique et la fluence linguistique auprès de locuteurs non-maternels et l'analyse de Gemma Santiago Alonso aborde l'acquisition de l'article défini dans le langage enfantin. Les articles suivants se réunissent autour du domaine de l'interprétation: Jana Zidar Forte présente une approche actuelle dans l'entrainement d'interprètes, Lea Burjan analyse les phénomènes issus de la pratique de l'interprétation juridique et Simona  Šumrada traite de la reformulation dans le discours de la traduction et de

  7. DU-AGG pilot plant design study

    International Nuclear Information System (INIS)

    Lessing, P.A.; Gillman, H.

    1996-07-01

    The Idaho National Engineering Laboratory (INEL) is developing new methods to produce high-density aggregate (artificial rock) primarily consisting of depleted uranium oxide. The objective is to develop a low-cost method whereby uranium oxide powder (UO[sub 2], U[sub 3]O[sub ]8, or UO[sub 3]) can be processed to produce high-density aggregate pieces (DU-AGG) having physical properties suitable for disposal in low-level radioactive disposal facilities or for use as a component of high-density concrete used as shielding for radioactive materials. A commercial company, G-M Systems, conducted a design study for a manufacturing pilot plant to process DU-AGG. The results of that study are included and summarized in this report. Also explained are design considerations, equipment capacities, the equipment list, system operation, layout of equipment in the plant, cost estimates, and the proposed plan and schedule

  8. L’écologie du coupable.

    Directory of Open Access Journals (Sweden)

    André Ourednik

    2006-04-01

    Full Text Available « Denn dass der Mensch erlöst werde von der Rache  : das ist mir die Brücke zur höchsten Hoffnung und ein Regenbogen nach langen Unwettern. » 1 Nous l’aurions presque oublié, en fouillant parmi les fondations du rapport moral au monde de nos sociétés, nous trouverons encore bien en place deux piliers érigés au cours du processus de la chrétienté : celui de l’ empathie et celui de la culpabilité . Le premier semble offrir le seul appui plausible à notre vivre ...

  9. DuPont Chemical Vapor Technical Report

    International Nuclear Information System (INIS)

    MOORE, T.L.

    2003-01-01

    DuPont Safety Resources was tasked with reviewing the current chemical vapor control practices and providing preventive recommendations on best commercial techniques to control worker exposures. The increased focus of the tank closure project to meet the 2024 Tri-Party Agreement (TPA) milestones has surfaced concerns among some CH2MHill employees and other interested parties. CH2MHill is committed to providing a safe working environment for employees and desires to safely manage the tank farm operations using appropriate control measures. To address worker concerns, CH2MHill has chartered a ''Chemical Vapors Project'' to integrate the activities of multiple CH2MHill project teams, and solicit the expertise of external resources, including an independent Industrial Hygiene expert panel, a communications consultant, and DuPont Safety Resources. Over a three-month time period, DuPont worked with CH2MHill ESH and Q, Industrial Hygiene, Engineering, and the independent expert panel to perform the assessment. The process included overview presentations, formal interviews, informal discussions, documentation review, and literature review. DuPont Safety Resources concluded that it is highly unlikely that workers in the tank farms are exposed to chemicals above established standards. Additionally, the conventional and radiological chemistry is understood, the inherent chemical hazards are known, and the risk associated with chemical vapor exposure is properly managed. The assessment highlighted management's commitment to addressing chemical vapor hazards and controlling the associated risks. Additionally, we found the Industrial Hygiene staff to be technically competent and well motivated. The tank characterization data resides in a comprehensive database containing the tank chemical compositions and relevant airborne concentrations

  10. Autour du paradigme d’écotourisme

    Directory of Open Access Journals (Sweden)

    Anne-Laure Transler

    2008-02-01

    Full Text Available L’écotourisme ouvre un cadre conceptuel original qui permet d’envisager des démarches renouvelées de développement à partir des revenus issus de consommations touristiques mieux réfléchies et organisées, susceptibles de soutenir des initiatives de développement local s’inscrivant dans un projet global de développement durable. Variante douce du tourisme, loin du tourisme de masse, le champ de l’écotourisme s’étend aux confins du tourisme de nature, du tourisme culturel et des pratiques scientifiques et sportives de plein air. Une définition de l’écotourisme peut être proposée à partir des six points suivants : 1/ nature et culture, 2/ le bien-être des sociétés hôtes, 3/ des touristes responsables, 4/ la participation des sociétés hôtes, 5/ la durabilité, 6/ l’art de la rencontre.Ecotourism provides an original conceptual framework that enables approaches to development that are better able to provide a more equitable distribution of income, as well as better organized and thought through initiatives which are more likely to promote a holistic sustainable local development. With somewhat less negative impact than normal tourism, considerably less that mass tourism, ecotourism can encompass nature tourism, cultural tourism, scientific exploration, and even outdoor sports... A definition of ecotourism should take into account the following six points: 1/ nature and culture, 2/ the welfare of the host community, tourists acting responsibly, 3/ participation by the local community, 5 / sustainability , 6/ promotion of cultural exchanges

  11. Le cas du Brésil

    International Development Research Centre (IDRC) Digital Library (Canada)

    pwust

    important volet des activités de coopération du Brésil dans les pays en développement, ...... attention à l'Amérique latine ou aux Caraïbes, malgré la priorité accordée à .... prudente et sélective face aux opérations triangulaires, afin d'éviter la ...

  12. Fès, la cybercapitale du Maroc

    International Development Research Centre (IDRC) Digital Library (Canada)

    Fès, la cybercapitale du Maroc. La ville de Fès est devenue un modèle primé en matière de mise en œuvre efficace des technologies de l'information et de la communication (TIC) dans les services publics d'un pays africain. ès, au Maroc. Dans une pièce renfermée datant des années 1950, des centaines de documents.

  13. Inventaire des champignons ectomycorhiziens du Maroc

    African Journals Online (AJOL)

    SARAH

    31 juil. 2014 ... RÉSUMÉ. Objectif : Le travail présenté ici a pour objectif de dresser, à partir de la bibliographie, l'inventaire des espèces ectomycorhiziennes du Maroc. Méthodologie et résultats : Les données sur les champignons, recueillies à partir de différents travaux publiés nous ont permis de réaliser un premier ...

  14. Les sens du musée

    Directory of Open Access Journals (Sweden)

    Laurent Grison

    1999-09-01

    Full Text Available Cet article, fondé sur l'exemple de la National Gallery de Londres, porte sur l'intégration dans le cadre urbain, l'aménagement et les dynamiques spatiales du lieu muséal. Sur le même thème, nous relatons un exercice réalisé avec des lycéens.

  15. Technostress et autres revers du travail nomade

    NARCIS (Netherlands)

    Popma, J.

    2013-01-01

    L'Internet et l'utilisation des ordinateurs portables, des téléphones mobiles et des tablettes ont accru l'importance du « travail nomade». Ce type de travail, sans contrainte de lieu ni de temps, peut entraîner, d’après ce working paper, une plus grande autonomie et une plus grande flexibilité pour

  16. KYSTE DERMOÏDE DU PLANCHER BUCCAL

    African Journals Online (AJOL)

    18 juin 2007 ... molle, indolore bien limitée, sessile ou pédiculée, lisse avec un aspect jaune caractéristique[10]. La palpation bidigitale, l'échographie associée à une ponc- tion cytologique, le scanner et au mieux l'IRM sont essen- tiels pour l'orientation étiologique devant toute lésion du plancher buccal [8]. En effet, l'IRM ...

  17. Administration des subventions du CRDI aux institutions :

    International Development Research Centre (IDRC) Digital Library (Canada)

    IDRC CRDI

    Comment puis-je réviser le budget de mon projet ? Le CRDI couvre-t-il les dépenses engagées en sus du montant de la subvention ? De quelle façon le CRDI transmet-il les fonds ? Mon institution doit-elle déposer les fonds reçus pour le projet dans un compte bancaire distinct ? Combien de temps faut-il au CRDI pour ...

  18. PersPectives du Programme acca

    International Development Research Centre (IDRC) Digital Library (Canada)

    à acca@crdi.ca. À propos du programme ACCA. Lancé en 2006, le programme Adaptation aux changements ... Nous pourrions y ajouter, par soucis d'équilibre, les « connus inconnus », c'est- à-dire les connaissances que nous ne ...... marocain m'a déjà dit ceci : « Je comprends vos préoccupations, mais mes questions ...

  19. Les Gammaridae (Crustaces, Amphipodes) du Massif Central

    NARCIS (Netherlands)

    Goedmakers, Annemarie

    1974-01-01

    Une prospection systématique des eaux courantes du Massif Central a permis de reconnaître le nombre d’espèces des Gammaridés présentes dans cette région. On a trouvé les espèces suivantes: Gammarus pulex (Linnaeus, 1758), G. fossarum Koch, 1835, et G. ibericus Margalef, 1951. G. ibericus, espèce

  20. L’écriture du temps dans Robinson Crusoe

    OpenAIRE

    Bulckaen, Denise

    2018-01-01

    “Le récit est une séquence deux fois temporelle... il y a le temps de la chose-racontée et le temps du récit (temps du signifié et temps du signifiant)”. Cette citation se trouve au début du chapitre que Genette consacre à “Ordre” dans Figures III. Elle s'applique à de nombreux romans, mais elle est particulièrement intéressante quand on considère le roman de forme autobiographique. Le décalage entre “le temps du signifié” et “le temps du signifiant” est plus ou moins grand selon les romans. ...

  1. [The Seongho () School's Study of the Ancient Learning () and Its Influence on the Debate about Materia Medica in the Late Joseon Dynasty].

    Science.gov (United States)

    Cho, Sung-San

    2015-08-01

    This study will determine the ways in which the ancient learning (gu xue, ) scholarship of the Seongho School, and its interest in the materia medica (ben cao xue, ) were related during the late Joseon period. The Seongho School centered its studies mainly on classical Chinese texts of the Han (206 BC-AD 220) and pre-Han (?-221 BC) (xian-qin lianghan, ) periods rather than those of the Tang and Song dynasties (618-1279). gu xue scholarship emerged during the Ming dynasty era (1368 -1644) as an alternative to the scholarly trends of the Song dynasty, which were dependent on Zhu Xi's (, 1130-1200) Neo-Confucianism and its interpretation of Han and pre-Han classical Chinese texts. This scholarly trend influenced Korean and Japanese literature, philosophy, and even medicine from the seventeenth through the nineteenth centuries. Focusing on Korean scholarship, we find a great deal of research regarding the influence of gu xue on Korean classical Chinese literature and Confucian philosophy in the late Joseon period; however, no study has examined how this style of scholarship influenced the field of medicine during the same period. This study will investigate how the intellectuals of the Seongho School, who did the most to develop gu xue among Joseon intellectuals, were influenced by this style of scholarship in their study of the materia medica. Jeong Yak-yong (1762-1836), the representative intellectual of the Seongho School, did not focus on complicated metaphysical medical theories, such as the Yin-Yang and Five Elements theory (yin yang wu xing shui, ) or the Five Movements and Six Atmospheres theory (wu yun liu qi shui, ). Instead, his interests lay in the exact diagnoses of diseases and meticulous herbal prescriptions which formed an essential part of the Treatise on Exogenous Febrile Disease (Shang han lun, ) written by Zhang Zhungjing (, 150-219) in the Han dynasty. The Treatise was compatible with the scholarly purpose of gu xue in that they both

  2. Enfants du soleil histoire de nos origines

    CERN Document Server

    Brahic, André

    1999-01-01

    D'où venons-nous ? Comment le Soleil et la Terre sont-ils apparus ? Nous avons enfin atteint le moment où la science peut apporter des réponses de plus en plus précises, de plus en plus étonnantes. La Nature a décidément plus d'imagination que les hommes ! Depuis l'exploration spatiale, nous en avons plus appris sur notre système solaire et son origine en une génération qu'en quarante siècles. Là où l'on attendait l'uniformité, on a trouvé la plus grande diversité. André Brahic, qui a découvert les anneaux de Neptune, nous présente les multiples facettes du système solaire et nous raconte quatre milliards et demi d'années de son histoire. Les planètes sont les soeurs du Soleil. Nous sommes les enfants du temps et des étoiles. Sommes-nous seuls dans l'Univers ? Les astronomes commencent à apercevoir d'autres planètes autour de quelques soleils proches, Ils espèrent bientôt trouver d'autres Terres...

  3. Ksenia Pimenova, Les sources de savoirs. Le renouveau du bouddhisme et du chamanisme chez les Touvas de la Sibérie du Sud

    OpenAIRE

    Pimenova, Ksenia

    2013-01-01

    Cette thèse présente une étude comparative du « renouveau » post-soviétique du chamanisme et du bouddhisme tibétain (école Guélougpa) chez les Touvas, un des peuples autochtones de la Sibérie du Sud (Russie). Ce phénomène a lieu après des décennies de politique antireligieuse (dès la fin des années 1920 jusqu’aux années 1980) ayant abouti à la destruction de la communauté bouddhique et à la marginalisation du chamanisme. Nous analysons le chamanisme et le bouddhisme post-soviétiques comme deu...

  4. Ved du, hvad der er i dine varer, når du handler?

    DEFF Research Database (Denmark)

    Phillip, Anja; Smith, Viktor

    2016-01-01

    I supermarkedet på vej hjem køber du ind til madpakken. Ved kølemontren med pålæg ser du en pakke Gårdlykke Hønsesalat. ... Måske vælger du den uden at tænke nærmere over hvorfor, eller fordi emballagen og navnet får hønsesalaten til at fremstå lokal, hjemmelavet eller økologisk. ... Alt dette ba...... bakkes op af resultaterne fra årelang forskning på CBS, hvor universitetets forskergruppe Fair-Speak har undersøgt emballagernes måde at påvirke forbrugerne til at købe produktet....

  5. 98 Etude Comparative du Systeme Phonematique et Tonal des ...

    African Journals Online (AJOL)

    98. Etude Comparative du Systeme Phonematique et Tonal des. Deux Parlers: Le Yoruba du Nigeria et L'itsa Parle en. Republique du Benin. Ajani Akinwumi Lateef et Ayuba G. Ajibabi http://dx.doi./org/10.4314/ujah.v18i3.5. Résume. En ce début de l'époque ou la mondialisation et la coexistence des peuples dans le ...

  6. Carcinome du tube collecteur de Bellini: une nouvelle observation ...

    African Journals Online (AJOL)

    Le carcinome du tube collecteur de Bellini est un type très rare des carcinomes à cellules rénales (CCR), sa fréquence est inférieure à 1%. Il dérive de la partie distale du néphron, plus précisément du tube collecteur. Ses aspects morphologiques sont extrêmement variables, rendant son diagnostic difficile. Nous rapportons ...

  7. Bourse du CRDI aux chercheurs candidats au doctorat 2018 | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Carrières · Communiquez avec nous · Plan du site. Abonnez-vous à notre bulletin pour recevoir les nouvelles du CRDI chaque mois. Abonnez-vous · Droits d'auteur · Éthique de la recherche · Politique de libre accès · Politique de confidentialité · Transparence · Utilisation du site Web. Suivez-nous; Facebook · Twitter ...

  8. Incorporation du coprah et des cuticules de cacao et d'arachide ...

    African Journals Online (AJOL)

    Incorporation du coprah et des cuticules de cacao et d'arachide dans l'aliment du ( tilapia du nil( ( Oreohromis niloticus , linné, 1758) eleve en etang : Effet sur la croissance et la composition biochimique.

  9. Matere z motnjami v duševnem razvoju

    OpenAIRE

    Kolarič, Sandra

    2015-01-01

    S pregledom tuje literature in že opravljenih raziskav v tujini smo v teoretičnem delu magistrske naloge zajeli značilnosti mater z motnjami v duševnem razvoju, dejavnike, ki vplivajo na uspešnost opravljanja materinske vloge, ter pravice oseb z motnjami v duševnem razvoju do starševstva, v povezavi z zakonodajo na slovenskem. Navedli smo vzroke za omejevanje reprodukcije pri ženskah z motnjami v duševnem razvoju in problematiko odvzema skrbništva materam z motnjami v duševnem razvoju nad otr...

  10. Autonomie du groupe restreint et performance

    Directory of Open Access Journals (Sweden)

    Elke Nissen

    2005-09-01

    Full Text Available Un groupe est autonome lorsqu'il prend lui-même en charge sa gestion (Abric, 1996 et lorsque celle-ci fonctionne bien. L'autonomie du groupe restreint est une caractéristique revendiquée dans le cadre actuel de l'expansion de dispositifs collaboratifs à distance entre apprenants. La question qui se pose alors est de savoir si un groupe restreint autonome est plus performant qu'un groupe moins autonome. L'autonomie d'un groupe d'apprentissage en ligne est-elle en relation avec la qualité de la réalisation de la tâche ? Est-elle en relation avec les progrès réalisés par les membres du groupe ? Dans le cadre de notre étude expérimentale, menée dans deux dispositifs pédagogiques différents (l'environnement d'apprentissage Babbelnet et une formation sur la plate-forme Acolad, des étudiants ont réalisé en groupes restreints, avec l'accompagnement d'un tuteur, une tâche de type actionnel – en l'occurrence une rédaction en langue étrangère (allemand ou anglais. Pour ce faire, ils disposaient d'aides méthodologiques et linguistiques dans l'environnement pédagogique en ligne. Ils ont interagi par le biais d'Internet au moyen de différents outils de communication. Une analyse de l'interaction qui a eu lieu dans chaque groupe, l'évaluation des rédactions réalisées conjointement, deux tests réalisés respectivement avant et après la phase de travail en groupe ainsi qu'un formulaire auto-administré nous permettent de mettre en lien l'autonomie des groupes, d'une part, et leur performance, voire leur apprentissage, d'autre part. Au vu de cette étude, il apparaît que l'autonomie du groupe n'a pas d'influence directe sur l'apprentissage des groupes restreints. En revanche, un rapport est visible entre l'appréciation du fonctionnement du groupe par ses membres et l'évolution de la performance des groupes.

  11. EQUILIBRE GLYCEMIQUE ET COMPLICATIONS MACROANGIOPATHIQUES DU DIABETE

    Directory of Open Access Journals (Sweden)

    Lyse BORDIER

    2017-05-01

    Full Text Available La question de l’efficacité d’un équilibre glycémique optimal dans la prévention des complications macroangiopathiques du diabète a fait l’objet d’une récente polémique. Si les faits sont clairs pour la microangiopathie notamment au cours du diabète de type 1, ils paraissent moins certains pour les complications cardiovasculaires du diabète de type 2. Cette constatation vient de l’intrication des autres facteurs de risque cardiovasculaires qui sont très fréquents chez ces patients. Cependant, les études de suivi sur une longue durée s’inscrivent en faveur de l’intérêt d’un bon équilibre glycémique sur les complications macroangiopathiques. Les résultats négatifs sur la mortalité de l’étude ACCORD et les inquiétudes concernant la rosiglitazone ont conduit à la mise en place d’études sur la sécurité d’utilisation des nouvelles molécules. Tous ces travaux ont abouti à la démonstration de l’absence de risque des iDPP-4 et de l’effet très positif de certaines molécules de la classe des analogues du GLP-1 et des iSGLT2.Il reste à espérer que la récente mise au point de l’Académie de Médecine soulignant que les complications du diabète de type 2 exigent une prévention multifactorielle qui passe obligatoirement par un contrôle optimisé de l'équilibre glycémique mette fin à une polémique inutile et dangereuse pour nos malades.

  12. Visite du Conseil des gouverneurs du CRDI en Afrique de l'Est ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    17 oct. 2017 ... La délégation dans la communauté La délégation à l'école féminine. La délégation avec les membres du Women's Group. Durant la visite, Jean Lebel et Molapo Qhobela, directeur général de la Fondation nationale de la recherche de l'Afrique du Sud, ont annoncé les projets retenus au Kenya et en ...

  13. An improved association-mining research for exploring Chinese herbal property theory: based on data of the Shennong's Classic of Materia Medica.

    Science.gov (United States)

    Jin, Rui; Lin, Zhi-jian; Xue, Chun-miao; Zhang, Bing

    2013-09-01

    Knowledge Discovery in Databases is gaining attention and raising new hopes for traditional Chinese medicine (TCM) researchers. It is a useful tool in understanding and deciphering TCM theories. Aiming for a better understanding of Chinese herbal property theory (CHPT), this paper performed an improved association rule learning to analyze semistructured text in the book entitled Shennong's Classic of Materia Medica. The text was firstly annotated and transformed to well-structured multidimensional data. Subsequently, an Apriori algorithm was employed for producing association rules after the sensitivity analysis of parameters. From the confirmed 120 resulting rules that described the intrinsic relationships between herbal property (qi, flavor and their combinations) and herbal efficacy, two novel fundamental principles underlying CHPT were acquired and further elucidated: (1) the many-to-one mapping of herbal efficacy to herbal property; (2) the nonrandom overlap between the related efficacy of qi and flavor. This work provided an innovative knowledge about CHPT, which would be helpful for its modern research.

  14. Les gloses botaniques andalouses sur le manuscrit de Paris de la traduction arabe de la Materia Medica de Dioscorides

    Directory of Open Access Journals (Sweden)

    Ben Mrad, Ibrahim

    2009-12-01

    Full Text Available The following study focusses on a precious manuscript from the National Library in Paris, namely n.º 2849 of the Arabic manuscript collection. This is a manuscript of Andalusian origin of the Arabic translation of Materia Medica by Dioscorides, written in Syria at the beginning of the 13th century. Its margins are filled with glosses of synonymic nature, relating to the Greek terms of the plants described by the Greek pharmacologist and physician. These glosses, of Andalusian origin, offer a great terminological richness which is part of a large Arabic — mainly Andalusian — movement of revision and commentary of Materia Medica in Arabic. In the first part a general introduction to the manuscript is provided showing its significant value for a critical edition of the book, the glosses contained and, especially, of the Andalusian botanical glosses, insisting on their synonymic value and their terminological contribution. In a second part, a critical annotated edition of 44 glosses from the first maqāla of the book is proposed.

    Se aborda en este trabajo el estudio de un precioso manuscrito de la Biblioteca Nacional de París, el n.º 2849 de los fondos árabes. Se trata de un manuscrito de origen andalusí que contiene la traducción al árabe de la Materia Medica de Dioscórides, escrito en Siria a principios del siglo XIII, cuyos márgenes están repletos de glosas de naturaleza sinonímica, relativas a los nombres griegos que reciben las plantas descritas por la farmacología griega. Estas glosas son de orígen andalusí, y ofrecen una gran riqueza terminológica que se inscribe en un amplio movimiento árabe, y más concretamente andalusí, de revisión y comentario de la traducción árabe de la Materia Medica. En la primera parte de este estudio se ofrece una presentación general del manuscrito, mostrando su valor para una reedición crítica de la obra, de las glosas que contiene y

  15. [Preliminary textual research on Zhijintang Sanctum re-revised version of Jinling edition of Ben cao gang mu (Compendium of Materia Medica)].

    Science.gov (United States)

    Zheng, Jinsheng

    2014-03-01

    The Zhijintang Sanctum version of the re-revised edition of Jinling edition of Ben cao gang mu (Compendium of Materia Medica)collected by Zhao Huiyuan of Baihe, Henan Province in 2008 was opted as one of the third batch of the National Directory of Rare Ancient Worksin 2010. On the second cover page (patent page), it is recorded as"Original Jiangxi version". However, it is investigated to find that most of its paper sheets were reprinted after the original Jinling version, only scores of paper sheets were supplemented block-printed, including the additional block-printed second preface and Li Jianyuan's submitted report of the Jiangxi version, the re-revised time of which should be after the Jiangxi edition, or 1603. The exact time can be determined only by checking it carefully against another Jinling re-revised version (the Sheyuantang Sanctum edition).

  16. Efeito da irrigação e medicação endodôntica em dentina infectada por biofilmes orais

    OpenAIRE

    Ronald Ordinola Zapata

    2013-01-01

    O objetivo desse estudo foi avaliar o efeito antimicrobiano da irrigação e da medicação endodôntica em dentina infectada por biofilmes orais. Na primeira parte do estudo, avaliaram-se as seguintes soluções irrigadoras: hipoclorito de sódio a 1%, clorexidina a 2%, ácido cítrico a 10% e EDTA a 17%. Na segunda parte, avaliaram-se soluções irrigadoras contendo associações (MTAD, Smear Clear, Qmix, ácido maleico a 7%, iodo-iodeto de potássio a 2% e ácido peracético a 4%), sendo essas soluções comp...

  17. Hausse du niveau des océans et perte de terres dans le delta du Nil ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    9 juin 2016 ... Au moyen de systèmes d'information géographique (SIG), des chercheurs subventionnés par le CRDI ont déterminé les zones littorales du delta du Nil qui pourraient être touchées par la hausse du niveau des océans. Il pourrait en résulter d'importantes pertes de terres d'ici 2100. Selon les plus récentes ...

  18. Le Silurien du Synclinorium de Moncorvo (NE du Portugal): Biostratigraphie et Importance Paléogéographique

    Czech Academy of Sciences Publication Activity Database

    Sarmiento, G. N.; Picarra, J. M.; Rebelo, J. A.; Robardet, M.; Gutiérrez-Marco, J. C.; Štorch, Petr; Rábano, I.

    1999-01-01

    Roč. 32, č. 5 (1999), s. 749-767 ISSN 0016-6995 R&D Projects: GA AV ČR Projects 351 et 421 du Programme International de Corrélation Géologique et au Projet Iberian Variscides du programme Europrobe, Projet 061-B0 du Programme de Coopération Scientifique et Technique Franco-Portugais Subject RIV: DB - Geology ; Mineralogy Impact factor: 0.736, year: 1999

  19. Gestion intégrée du mildiou du mil en station au centre régional de ...

    African Journals Online (AJOL)

    user

    Le mil (Pennicetum glaucum) L.R.Br constitue 75% de la production céréalière du Niger. Cependant, son rendement est très faible dû à plusieurs types de contraintes. La maladie du mildiou du mil causé par un champignon Sclerospora graminicola (Sacc) Schroët, occupe une place importante. L'objectif de cette étude.

  20. A pré-medicação com midazolam antes de secção cesariana não tem efeitos adversos no neonato

    Directory of Open Access Journals (Sweden)

    Ahmet Can Senel

    2014-01-01

    Full Text Available Como todos os pacientes cirúrgicos, pacientes obstétricas também sentem estresse e ansieda de operatórios. Isso pode ser prevenido se forem passadas à paciente informações detalhadas sobre sua operação e se forem administrados medicamentos farmacológicos pré-operatórios. Devido aos efeitos depressivos dos sedativos nos neonatos, os medicamentos farmacológicos são omitidos, especialmente em pacientes obstétricas. A literatura contém poucos estudos concernentes ao uso de midazolam no pré-operatório em pacientes de secção cesariana (C/S. Nosso objetivo nesse estudo foi ajudar nossas pacientes passando por cirurgia C/S. Um grupo agendado para C/S eletiva recebeu midazolam 0,025 mg kg−1 por via intraveno sa; o outro grupo recebeu salina. A ansiedade materna foi avaliada com o uso dos escores da Amsterdam Preoperative Anxiety and Information Scale (APAIS (Escala de Ansiedade e Informação Pré-operatória de Amsterdam, e os neonatos foram avaliados por Apgar e pelo instrumento Neonatal Neurologic and Adaptive Capacity Score (NACS (Escore Neurológico e de Capacidade Adaptativa do Neonato. Em conclusão, os pacientes pré-medicados com midazolam 0,025 mg kg−1 medicação tiveram escores de ansiedade significativamente baixos, sem qualquer efeito adverso nos neonatos. Portanto, midazolam pode, com segurança, ser utilizado como agente de pré-medicação na cirurgia C/S.

  1. Fiche pratique: Des proverbes en pagaille; Debat filme; Faire un journal televise; Du bon usage d'un medicament (Practical Ideas: Proverbs in a Muddle; Filmed Debate; To Make a Televised Journal; Good Use of a Medicine).

    Science.gov (United States)

    Lisboa, Maria Fernanda Araujo; And Others

    1996-01-01

    Four French language class activities are described, including a game using proverbs to review animal names and encourage comprehension; videotaping a class debate in French, to promote both exchange of ideas and student confidence before a group; a role-playing exercise in which a television news program is created; and a specialized activity to…

  2. Progrès de la connaissance du Congo, du Rwanda et du Burundi de 1993 à 2008

    Directory of Open Access Journals (Sweden)

    Henri Nicolaï

    2013-03-01

    Full Text Available Cette chronique, la vingt et unième d’une série qui a commencé avec l’année 1949, couvre la période 1993-2008 et a pour objectif de faire le point sur les progrès réalisés sur la connaissance du Congo (République démocratique du Congo, du Rwanda et du Burundi, dans le domaine de la géographie mais aussi dans les domaines des sciences naturelles et des sciences humaines qui peuvent fournir des données utiles ou indispensables aux géographes. Chaque référence bibliographique, livre ou article, est accompagnée d’un bref commentaire qui en retient les éléments principaux et surtout les faits ou les idées qui intéressent particulièrement les géographes. L’article comporte onze chapitres dont les plus importants concernent le milieu naturel, la géographie de la santé, la démographie, l’histoire (y compris l’histoire récente, la vie sociale et économique des campagnes traditionnelles et modernes, le secteur informel, les aspects de la vie urbaine. Les événements dramatiques qui se sont produits dans ces territoires africains au cours des quinze dernières années ont rendu la recherche sur le terrain particulièrement difficile tant pour les chercheurs nationaux que pour les chercheurs étrangers, ce qui se traduit notamment par une part de plus en plus importante des recherches menées en milieu urbain.This paper, the 21st issue of an edition of books and paper reviews on the knowledge of three countries of former Belgian Africa (DR Congo, Rwanda, and Burundi, covers the period 1993-2008. A short text for each reference points out the facts or ideas that are useful for geographers. The paper is composed of eleven sections. The most important are coping with the natural environment, health geography, population geography, history (including recent events, social and economic life in traditional and modern rural areas, informal economy, and urban geography. During the last sixteen years, conditions for field

  3. Un Genevois coopte a la tete du Front islamique du salut

    CERN Multimedia

    Merckling, N

    2002-01-01

    "Le Front islamique du salut (FIS), a nomme a la tete de ce parti fondamentaliste un resident genevois, Mourad Dhani, chois parmi trois candidats. Ce physicien algerien est arrive a Geneve il y a 14 ans pour travailler au CERN (1 page).

  4. La ministre Bibeau annonce la nomination du président du CRDI et ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    il y a 5 jours ... ... et chargé de cours associé à l'Université Griffith de South East Queensland, en Australie. Ancien professeur adjoint auxiliaire à la School of International and Public Affairs de l'Université Columbia, à New York; et ancien chercheur du Centre international pour la recherche en agroforesterie, à Nairobi.

  5. 73 Utilisation du SIG pour une réorganisation urbaine du centre-ville ...

    African Journals Online (AJOL)

    TOHOZIN

    restructuration des routes, du chemin de fer, des bâtis et des cours d'eaux. ... aussi la réalisation d'une mappe foncière qui est un instrument capital en matière ..... confirmer que le SIG, en tant qu'outil de décision et de planification a ...

  6. Résultats du traitement chirurgical des traumatismes du rachis à l ...

    African Journals Online (AJOL)

    incomplète était prédictive de bon pronostic P< 0,001. Les traumatismes du rachis cervical sont des urgences neurologiques qui mettent en jeu le pronostic vital et fonctionnel des patients. Mots clés : Traumatisme, rachis, traitement. The purpose of this series was to describe the results of surgical treatment of spinal injury.

  7. ETUDE DU COMPORTEMENT MECANIQUE DU BETON CELLULAIRE AUTOCLAVE PRODUIT EN ALGERIE

    Directory of Open Access Journals (Sweden)

    R BELOUETTAR

    2002-12-01

    Full Text Available Ce travail présente une étude expérimentale du comportement mécanique du béton cellulaire autoclavé. L’étude est portée essentiellement sur une série d’essais mécaniques en compression quasistatique à différentes vitesses de déformation variables entre 10-4 s-1 et 10 s-1 et à deux états différents (état sec et état saturé d’eau. En général, l’augmentation de la vitesse de déformation donne une augmentation de la contrainte critique du béton cellulaire autoclavé. Le béton cellulaire autoclavé présente une sensibilité à la vitesse de déformation positive. La valeur du module d’élasticité est proche de la valeur standard (1.5 GPa pour un béton cellulaire autoclavé de masse volumique égale à 500-550 kg/m3.

  8. La reconstruction du sourcil par greffon composite du cuir chevelu: une astuce pour faciliter la technique

    Science.gov (United States)

    El Omari, Mounia; El Mazouz, Samir; Gharib, Noureddine; EL Abbassi, Abdallah

    2015-01-01

    Les sourcils jouent un rôle important dans l’équilibre esthétique du visage. Leur reconstruction ou ophriopoïése, après séquelle de brûlure fait partie intégrante du programme de réhabilitation de la face brûlée. Plusieurs techniques ont été décrites. Nous insistons ici sur l'intérêt d'une technique simple, à la portée de tous les chirurgiens, et dont la méthode et les résultats peuvent être améliorés par un dessin bien planifié des zones donneuse et receveuse: la greffe composite prélevée au niveau du cuir chevelu dessinée à l'aide d'un calque du sourcil controlatéral. PMID:26401195

  9. Lignes directrices du CRDI pour la préparation du rapport technique

    International Development Research Centre (IDRC) Digital Library (Canada)

    fdieudonne

    l'accord de subvention et doivent faire partie de tout rapport hébergé dans la ... questions de nature délicate ou confidentielle doivent être traitées par un échange .... les innovations relevant des sciences, de la recherche ou du savoir;.

  10. L'aventure du grand collisionneur LHC du big bang au boson de Higgs

    CERN Document Server

    Denegri, Daniel; Hoecker, Andreas; Roos, Lydia; Rubbia, Carlo

    2014-01-01

    Qu'est-ce que la physique des particules élémentaires, le LHC, et le boson de Higgs ? Ce livre présente de manière simple le monde des quarks, des leptons et de leurs interactions, gouvernées par des symétries fondamentales de la nature, ainsi que le lien entre ce monde de l'infiniment petit et celui de l'infiniment grand. Cette conjonction entre la physique des particules élémentaires et l'évolution de la matière dans les premiers instants de l Univers qui ont suivi le Big-Bang est un des plus beaux acquis de la science de ces cinquante dernières années. Après une description du cadre théorique, le modèle standard, et de son élaboration durant la deuxième moitié du XXe siècle, l'accent est mis sur ses grands succès expérimentaux, mais aussi sur ses faiblesses ou insuffisances telles que nous les percevons aujourd'hui. La passionnante histoire du grand collisionneur de hadrons du CERN, le LHC, le plus grand projet purement scientifique jamais réalisé, est présentée à la fois sous ses...

  11. Une brève histoire du temps du Big Bang aux trous noirs

    CERN Document Server

    Hawking, Stephen

    2017-01-01

    Stephen Hawking est universellement reconnu comme l'un des plus grands cosmologistes de notre époque et l'un des plus brillants physiciens depuis Einstein. Successeur de Newton, il occupe à l'université de Cambridge la chaire de Mathématiques, et s'est rendu célèbre pour ses travaux sur les origines de l'Univers. Une brève histoire du temps est le premier livre qu'il ait décidé d'écrire pour le non-spécialiste. Il y expose, dans un langage simple et accessible, les plus récents développements de l'astrophysique concernant la nature du temps et du monde. Retraçant les grandes théories du cosmos, de Galilée et Newton à Einstein et Poincaré, racontant les ultimes découvertes de l'espace, expliquant la nature des trous noirs, il propose ensuite de relever le plus grand défi de la science moderne : la recherche d'une théorie unitaire combinant et unifiant la relativité générale et la mécanique quantique. On sait que Stephen Hawking lutte depuis plus de trente ans contre une maladie neurolo...

  12. Harmful effects of DU in the offspring of the military personnel employed in DU contaminated regions

    International Nuclear Information System (INIS)

    Atlagic, N.; Lisov, Lj.; Barjaktarovic, V.; Djurovic, B.; Spasic, Jokic V.

    2008-01-01

    Full text: In 1999, during the NATO attacks on Kosovo, from AT-10 aircraft has been shot over 50000 30-mm projectiles which contained approximately 15 tones of DU. Besides DU, projectiles contained products of DU radioactive decay as well as americium, neptunium, plutonium and technetium. Due to DU contamination military personnel employed near hit targets could be contaminated and irradiated. Besides the harmful effects in exposed military personnel, harmful effects were noticed in their offsprings, too. DU can cause genetic and teratogenic harmful effects in the embryos/fetus. It is concentrated in semen of contaminated males and also can contaminate the embryo/fetus through placenta. DU, as a toxic and radioactive element, can cause variety of harmful effects, but the most important are the effects on DNA which are the cause of many diseases. The aim of this paper is to examine is there any change in the incidence in heritable effects, congenital malformations, malignant diseases, endocrine and immune disorders. For that reason we compared the incidence of these diseases in the offspring's of military personnel born from 1995-1999 (1204) with the children born from 2000-2004 (1131) / and 2005-2008. Our results showed higher incidence of congenital malformations and chromosomal abnormalities (12.55 % vs 4.57 %), with highest incidence of foot deformity-52.04 % and hip deformity. These abnormalities were followed with immunological disorders and dysfunction of the urine bladder. Endocrine diseases were increased too(2.16 % :1.63 %). In this period higher incidence of malignant diseases was not noticed, but in the second period (from 5-9 year) after 1999, higher incidence of malignant hematological diseases was noticed, as well as Down Sy. During the conflicts future parents as well as embryo/fetus are exposed to many harmfulness and it is very hard to separate the influence of each. Considering the fact that the effects of DU, could be delayed and synergistic with

  13. Suivi après le traitement du cancer du sein

    Science.gov (United States)

    Sisler, Jeffrey; Chaput, Geneviève; Sussman, Jonathan; Ozokwelu, Emmanuel

    2016-01-01

    Résumé Objectif Offrir aux médecins de famille un résumé des recommandations fondées sur les données probantes pour guider les soins aux survivantes traitées pour le cancer du sein. Qualité des données Une recherche documentaire a été effectuée dans MEDLINE entre 2000 et 2016 à l’aide des mots-clés anglais suivants : breast cancer, survivorship, follow-up care, aftercare, guidelines et survivorship care plans, en se concentrant sur la revue des lignes directrices publiées récemment par les organismes nationaux de cancérologie. Les données étaient de niveaux I à III. Message principal Les soins aux survivantes comportent 4 facettes : surveillance et dépistage, prise en charge des effets à long terme, promotion de la santé et coordination des soins. La surveillance des récidives ne se traduit que par une mammographie annuelle, et le dépistage d’autres cancers doit suivre les lignes directrices basées sur la population. La prise en charge des effets à long terme du cancer et de son traitement aborde des problèmes courants tels la douleur, la fatigue, le lymphœdème, la détresse et les effets indésirables des médicaments, de même que les préoccupations à long terme comme la santé du cœur et des os. La promotion de la santé met en relief les bienfaits de l’activité chez les survivantes du cancer, avec l’accent mis sur l’activité physique. Les soins aux survivantes sont de meilleure qualité lorsque divers services et professionnels de la santé participent aux soins, et le médecin de famille joue un rôle important dans la coordination des soins. Conclusion Les médecins de famille sont de plus en plus souvent les principaux fournisseurs de soins de suivi après le traitement du cancer du sein. Le cancer du sein doit être considéré comme une affection médicale chronique, même chez les femmes en rémission, et les patientes profitent de la même approche que celle utilisée pour les autres affections chroniques en

  14. Le devenir actif du corps affectif

    Directory of Open Access Journals (Sweden)

    Pascal Séverac

    2005-09-01

    Full Text Available Le but de cet article est de saisir ce que signifie, pour le corps, être actif. À partir de la proposition 49 de la partie IV de l’Éthique, on propose de distinguer deux manières d’appréhender le corps – soit comme corps organique, soit comme corps affectif -, et l’on montre que la question éthique du devenir actif s’adresse à la dimension affective du corps. Il faut penser le devenir actif du corps affectif comme augmentation de son aptitude non seulement à affecter, mais aussi à être affecté. En effet, être affecté pour le corps n’est pas identique à pâtir : au contraire, plus est grande l’ouverture sensible d’un corps aux autres corps, plus est grande son activité éthique.The aim of this paper is to understand how the body can be active. With the proposition 49 of the fourth part of Ethics, two ways of conceiving of the body are distinguished : like an organic body or like an affective body. The ethics question of becoming active is about the affective body. This becoming active must be understood as increasing of the ability to affect, as well as to be affected. To be affected is different from to be passive. On the contrary, the more the body is able to be affected, the more he becomes active.

  15. vARIATIONS MENSUELLES DURANT TROIS ANNÉES DU ...

    African Journals Online (AJOL)

    , Université .... ont reçu une alimentation à base de pâturage de. Panicum maximum avec ... Variations mensuelles durant trois années du nombre de spermatozoïdes par éjaculat et des paramètres de spermocytogramme du sperme de bélier ...

  16. Les physiciens du CERN se font batisseurs de cavernes

    CERN Multimedia

    Augereau, J F

    2002-01-01

    Pour percer les secrets bien gardes de la nature, en particulier les origines de la masse, les chercheurs vont installer dans une de ces grottes un enorme detecteur de particules. Atlas, c'est son nom, sera place sur le trace du plus grand accelerateur du monde pour recueillir des indices (1 page).

  17. pluviosite en region soudano-sahelienne au nord du cameroun

    African Journals Online (AJOL)

    AISA

    Dans le but de montrer qu'en zone soudano-sahélienne du Nord du ... principaux facteurs responsables de la variation des rendements en culture pluviale, une étude basée sur ... Mots clés : Risque climatique, pluviométrie, variation, rendement agricole, Nord Cameroun. ... d'analyse plus global et fonctionnel, à savoir,.

  18. Petites entreprises en Afrique: Clés du Changement

    International Development Research Centre (IDRC) Digital Library (Canada)

    Petites et moyennes entreprises — Politique gouvernementale — Afrique — ...... d'adhérer aux stratégies et aux politiques visant à assurer le développement ...... Qui plus est, les banques ont du mal à recruter du personnel de direction et de ...

  19. Connaissances, attitudes, pratiques et appréciations du personnel ...

    African Journals Online (AJOL)

    Connaissances, attitudes, pratiques et appréciations du personnel médical du CHU-Tokoin sur le rôle de la pharmacie hospitalière dans sa mission d'appui au fonctionnement des unités de soins et de diagnostic.

  20. Appel à propositions pour le concours de 2018 du Programme ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    23 nov. 2017 ... Zipline uses drone technology to save lives. Sarah Farhat / Banque mondiale. Le CRDI, l'Israel Science Foundation, la Fondation Azrieli et les Instituts de recherche en santé du Canada annoncent l'appel de propositions pour la quatrième ronde du Programme conjoint canado-israélien de recherche en ...

  1. Renforcement de la lutte antitabac en Afrique du Sud | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    affichage de mises en garde sur les produits du tabac (l'équipe doit encore proposer des messages, les soumettre à un groupe test et les évaluer) et de délimiter des zones sans fumée pour les spectateurs de la Coupe du monde de football de 2010.

  2. Funcionamento intelectual em pacientes pediátricos com epilepsia: comparação de crianças controladas com medicação, não controladas com medicação e controladas com cirurgia Intellectual functioning in pediatric patients with epilepsy: a comparison of medically controlled, medically uncontrolled and surgically controlled children

    Directory of Open Access Journals (Sweden)

    Cecília Souza-Oliveira

    2010-10-01

    Full Text Available OBJETIVO: Comparar o quociente intelectual (QI em três grupos de crianças com epilepsia: 1 controlados com medicação, 2 não controlados com medicação e 3 controlados com cirurgia. MÉTODOS: Noventa e oito pacientes pediátricos, com idades entre 6 e 12 anos, foram selecionados de dezembro de 2007 a julho de 2008. A Escala de Inteligência Wechsler para Crianças - terceira edição (WISC-III foi utilizada para a avaliação neuropsicológica dos pacientes. Os resultados foram relacionados com a síndrome epiléptica, a etiologia da epilepsia, o tratamento medicamentoso, a idade do paciente no início da epilepsia e a duração da epilepsia. RESULTADOS: Os escores da WISC foram significativamente melhores no grupo controlado com medicação quando comparados aos do grupo não controlado com medicação. O grupo controlado com medicação obteve um desempenho significativamente melhor na maioria dos subtestes da WISC quando comparado ao grupo não controlado com medicação: vocabulário, aritmética, compreensão, memória de dígitos, completar figuras, arranjo de figuras e cubos. Um número significativamente maior de pacientes com epilepsia idiopática e uso de monoterapia foi observado no grupo controlado com medicação quando comparado ao grupo não controlado. O grupo controlado com cirurgia não apresentou diferença significativa no desempenho do QI quando comparado ao grupo controlado com medicação. CONCLUSÕES: As crianças com um bom controle de crises tiveram um melhor desempenho no QI geral, verbal e de execução quando comparadas às crianças com epilepsia refratária. Esses resultados podem ser influenciados por fatores clínicos como o uso de monoterapia, o tipo de droga antiepiléptica utilizada, a síndrome epiléptica e a etiologia da epilepsia. A cirurgia de epilepsia pode causar um impacto positivo no desempenho cognitivo das crianças que ficaram livres de crises após o procedimento cirúrgico.OBJECTIVE: To

  3. Fondements du projet urbain ; enjeux et processus

    OpenAIRE

    Tabouret , René

    1989-01-01

    Ce rapport retrace l’émergence et la formalisation progressive du concept de projet urbain dans le cadre de l’Ecole d’Architecture de Strasbourg sur une décennie (1978-1988), à l’épreuve de projets contrastés (villes de Mulhouse, St Denis, Strasbourg) et de la participation au Seminario Internazionale de Arquitectura Contemporanea (sessions de Barcelone, Naples et Belfort). La projet urbain y est identifié comme ‘intervention dans le processus complexe de (trans)formation de la ville’ ; ceci ...

  4. EPIDEMIOLOGIE DE LA PANACHURE JAUNE DU RIZ ...

    African Journals Online (AJOL)

    AISA

    Dans le but de connaître la situation épidémiologique de la panachure jaune du riz en côte d'Ivoire, une enquête phytosanitaire a été effectuée au cours des campagnes agricoles en 2004 et 2005. Elle a porté sur. 128 rizières irriguées et pluviales de 28 localités représentatives dans la moitié sud de la Côte d'Ivoire. Sur.

  5. Metabolisme protéico-muscular a l'obesitat

    OpenAIRE

    Yebras Cañellas, Martí

    1995-01-01

    Resultats anteriors mostraven que rates amb obesitat nutricional ("dieta de cafeteria") tenien un perfil metabòlic d'estalvi de nitrogen, mentre que pel model d'obesitat genètica (Zucker (fa/fa)) es suggeria un malbaratament de nitrogen. Es mostra una reducció en la taxa de recanvi d'alanina per l'animal sencer en el model d'obesitat nutricional, i un increment en el model d'obesitat genètica. La fracció anabòlica de la taxa és la responsable d'aquestes alteracions, suggerint perturbacions en...

  6. The metabolisme of tritiated water in the rat

    International Nuclear Information System (INIS)

    Jeanmaire, Lucien; Vernois, Yvette; Bullier, Denise; Gros, Roger.

    1977-07-01

    The metabolism of tritiated water was studied in the rat during 580 days. The results on urinary and fecal excretion, total activity retention in 25 tissues or organs, cumulated activities from the 4th to the 582nd day are presented and discussed. They are in agreement with other similar studies, if compared over the same length of experimentation. The activity retained by the spinal cord is twice that retained in the brain considered as the organ whose long half-lived component is the most active. The use of such data for the study of tritium-labelled compounds is illustrated by two examples [fr

  7. Festival du rire de Genève

    CERN Document Server

    Staff Association

    2015-01-01

    Connaissez-vous le Festival du rire de Genève ? La deuxième édition aura lieu du 25 au 28 mars 2015 au Casino-Théâtre à Carouge. Côté programmation, Marc Donnet-Monay ouvre les festivités avant trois autres soirées de folie et d’humour que nous vous laissons le soin de découvrir dans le programme : http://www.rire-geneve.ch/#programme. Réduction de 30% sur l’achat de places pour les membres du personnel du CERN. Pour cela, il suffit de se rendre sur la billetterie en ligne de notre site : www.rire-geneve.ch et d’utiliser le code promotionnel. Contacter le secrétariat de l’Association du personnel (Staff.Association@cern.ch) pour connaitre ce code promotionnel.

  8. La longue marche du mouvement sportif camerounais : l'émergence du Comité Olympique Camerounais (1946–1964

    Directory of Open Access Journals (Sweden)

    Charitas Pascal

    2016-01-01

    Dans ces conditions et selon le statut particulier de ce territoire du « pré-carré » africain de la France, il s'agit de comprendre les étapes de l'institutionnalisation du sport camerounais au sein des atermoiements de la colonisation française puis les processus à l'œuvre dans l'émergence puis la création du Comité Olympique Camerounais (COC, symbole de l'émancipation du sport camerounais et marqueur de son intégration sur la scène sportive internationale, plus particulièrement olympique. Autrement dit, de 1946 et la mise sous tutelle par l'ONU du Cameroun français pour sa partie orientale à 1964 et la première participation du CNO du Cameroun aux Jeux olympiques de Tokyo, l'objectif est de saisir ici le passage d'un sport colonial à un sport postcolonial mettant en exergue le rôle de l'influence française et le rôle des cadres camerounais du secteur sportif.

  9. Performances comparées du HDL-cholestérol et du ratio cholestérol ...

    African Journals Online (AJOL)

    Pour le dépistage du SMet, l'AUC du CT/HDL-C est de 0,69 (IC 95% 0,61-0,77) chez les ... high blood pressure (BP), high fasting glucose, low HDL-C and high triglycerides. Areas under the "Receiver operator characteristic" curves (AUC)

  10. "Cet obscur objet du Désir"

    Directory of Open Access Journals (Sweden)

    Reto Melchior

    1996-09-01

    Full Text Available Luis Bunuel’s last film is based on Pierre Louÿs’ La Femme et le Pantin. This now forgotten bestseller, published in 1898, is drawn from Goya s painting El Pelele, in which four women are playing with a male puppet. In Pierre Louÿs’ novel this scene is inverted so that one woman with two faces plays with four men. In Cet Obscur Objet du Désir this “femme fatale” is interpreted by two actresses. The concentric structure of the film puts focus on a scene of being excluded from knowing. The technique of continually interrupting the flash-back sequences frustrates the audience because of its exclusion from the “real” course of events and gives rise to doubts whether the male protagonist tells the truth about his love-affair or whether he satisfies the curiosity of the audience by telling them Pierre Louÿs’ novel as his own story. This ambiguous art of narration mirrors Bunuel’s claim that the main topic of Cet Obscur Objet du Désir is frustration.

  11. La dimension publicitaire du storytelling politique

    Directory of Open Access Journals (Sweden)

    Andreea Monica State

    2016-11-01

    Full Text Available Le thème général de cet article fait référence à la dimension publicitaire de la narration politique. J'ai choisi ce sujet parce que les histoires font partie de la vie humaine depuis longtemps, utilisées pour transmettre la tradition et enseigner des modèles de comportement social. Récemment, des histoires ont été utilisées de plus en plus souvent à des fins diverses telles que la publicité, la gestion ou la politique. Cet article vise à réaliser une recherche qualitative qui combine l'analyse du contenu et l'analyse du discours. En dehors de la base théorique qui vise à clarifier les concepts de base de la recherche, j’étudie la narration politique utilisée par l'ancien Président Traian Basescu et l'ancien Premier Ministre Victor Ponta dans les biographies en ligne, puis une analyse de leurs discours lors de la Fête Nationale de la Roumanie et l'Union des Principautés Roumaines.

  12. Erros de medicação em hospitais: uma análise bioética dos aspectos jurídicos e de saúde

    Directory of Open Access Journals (Sweden)

    Gabriela Souza Schumacher

    2013-06-01

    Full Text Available Introdução: O tema dos erros de medicação envolve vários aspectos - éticos, morais, jurídicos, sociais, profissionais, assistenciais, entre outros - merecendo uma reflexão abrangente. Os aspectos éticos referem-se principalmente à adequação das ações frente aos erros e os aspectos jurídicos estão relacionados diretamente com a aferição da responsabilidade civil nos casos da ocorrência de danos. Este estudo busca estabelecer relações entre o Direito, a Saúde e a Bioética, em uma perspectiva interdisciplinar, por meio da avaliação dos acórdãos referentes a erros de medicação em hospitais na jurisprudência do Rio Grande do Sul. Materiais e Método: Foi realizada uma pesquisa qualitativa, de análise de conteúdo documental, em acórdãos colhidos na base de dados eletrônica do Tribunal de Justiça do estado do Rio Grande do Sul. O descritor utilizado para busca foi: erro de medicação em hospitais. Resultados e Discussão: foram localizados 43 acórdãos na base de dados no período de 1995 a 2011. Destes, apenas 6 acórdãos referem-se a erros de medicação especificamente, sendo que 2 não estão disponíveis na íntegra. Foram analisados os quatro acórdãos envolvendo erros de medicação. Nos 4 acórdãos os demandados foram: 3 hospitais, 1 município e 1 médico. Todas as decisões foram favoráveis aos demandantes. Considerações Finais: O conceito de erro de medicação, embora utilizado na área da saúde e por órgãos oficiais, não tem sido utilizado no Poder Judiciário, o que demonstra que uma maior aproximação das áreas envolvidas, incluindo uma melhor comunicação, é necessária para uma adequada compreensão do tema.

  13. Profile counting; Comptage suivant l'axe principal du corps; Issledovanie schetchikom vdol' vsego tela; Recuento segun el eje principal del cuerpo

    Energy Technology Data Exchange (ETDEWEB)

    Pochin, E E [Medical Research Council, Department of Clinical Research, University College Hospital Medical School, University Street, London, W. C. 1 (United Kingdom)

    1959-07-01

    des radioisotopes dans le corps. Quand un isotope approprie est concentre selectivement dans certains organes ou tissus du corps, le presente des pointes indiquant l'emplacement et les dimensions de ces concentrations, les organes affectes peuvent alors etre identifies au moyen de doubles visees; on poursuit le comptage le long de l'axe principal du corps, afin de suivre le debit ou les changements de concentration dans ces organes. Cette technique a ete mise en oeuvre pour etudier la concentration et le metabolisme de l'iode-131 dans les cancers de la thyroide; son utilite pour le mode de traitement de ces tumeurs au moyen du radioiode sera examinee. La meme technique a ete adoptee pour etudier la repartition de la thyroxine et de la triiodothyronine marquees apres injection intraveineuse et celle de particules d'oxyde d'yttrium-90 apres injection arterielle intrapulmonaire , ainsi que pour determiner la repartition d'autres isotopes d'apres l'irradiation gamma ou le rayonnement de freinage. Cette methode permet une simplification, utile en recherche clinique, du releve graphique complet du corps humain; elle se prete particulierement a la comparaison quantitative de la repartition des isotopes a des intervalles differents, apres une ou plusieurs doses successives de radioisotopes. (author) [Spanish] En el recuento segun el eje principal del cuerpo, se desplaza progresivarnente un contador a lo largo de todo el organismo, colimandolo de tal forma que, en cada posicion, registre la cantidad de radioisotopos contenida en toda la anchura del cuerpo y solamente en una pequena seccion de su longitud. Si se representa graficamente el indice de recuento en funcion de la distancia del contador a la parte superior de la cabeza, se obtiene un ''perfil'' que proporciona una medida rapida y cuantitativa de la distribucion de los radioisotopos en el organismo. Cuando un isotopo adecuado este concentrado de modo selectivo en determinados organos o tejidos del organismo

  14. DU weaponry: a view on facts and deceptions

    International Nuclear Information System (INIS)

    Joksimovich, V.

    2002-01-01

    The paper summarizes the results of literature research conducted by the author on the use of depleted uranium (DU) weaponry. The research was initiated during the NATO bombing of Yugoslavia in 1999 with an objective of searching for facts in the presence of massive deceptions staged by the huge propaganda machinery of DU weaponry use proponents. The U.S. made use of DU penetrators in the Persian Gulf war as well as in the Balkan wars both in Bosnia and Kosovo. Brief science and history backgrounds are provided including overviews of DU uses and abuses in these three wars. The U.S./NATO public pronouncements have been centered around the theme that there has been no proven link between DU and cancers. In the author's view, these types of carefully word engineered statements are motivated by possible compensation and cleanup claims rather than supported by hard data and sound science. Since underlying causes of so called Gulf and Balkan syndromes have not been found despite a decade elapsed since conclusion of the Persian Gulf War, the DU must continue to be a front-line suspect. From the standpoint of public health and safety, it is prudent and responsible to call for a moratorium. DU use in the Kosovo war, which was not sanctioned by the UN Security Council, was reckless in the extreme. (author)

  15. Depleted uranium (DU) mobility in the natural environment

    International Nuclear Information System (INIS)

    Ragnarsdottir, K.V.

    2002-01-01

    In 1999 the Balkan's conflict lead NATO war planes to leave 10x10 3 kg of depleted uranium (DU) in the environment of Kosovo and neighbouring states (UNEP, 2001). DU behaves in the same manner in the environment as natural uranium and it can be traced with isotopic analysis due to the fact that DU has the isotopic composition of 0.2% 235 U and 99.8% 2 38 U as opposed to natural uranium which has 0.7% 2 35 U and 99.3% 2 38 U. DU is a waste product of the nuclear industry which enrich nuclear fuel by 2 35 U. Large stock piles of DU therefore exist in countries that produce nuclear energy and/or nuclear weapons. The DU is given to the weapons industry for free (or cheap) and has been a popular choice for armour penetrating arsenal due to the high density of uranium (19 g cm -3 ) and therefore its high penetrating power. Indeed the arsenal used in Kosovo consisted of DU penetrators that were shot from A-10 aeroplanes. They weigh roughly 300 g and have the shape of a fat 9 cm long pencil. (author)

  16. Roman contre roman dans l’organisation du manuscrit du Vatican, Regina Latina 1725

    Directory of Open Access Journals (Sweden)

    Francis Gingras

    2012-08-01

    Full Text Available Alors que les développements structuralistes et post-structuralistes ont favorisé la “textualisation” de la littérature médiévale, l’auteur suggère que la recontextualisation de la réception du roman médiéval passe par un retour aux manuscrits. Appliquée au manuscrit du Vatican, Regina Latina 1725, cette hypothèse de recherche révèle une technique de contrepoint que permet la juxtaposition de différents romans et dont, en dernier recours, le lecteur est toujours un peu juge.

  17. Strategie de repeuplement du mollusque gasteropode Concholepas concholepas (B) au sud du Chili

    OpenAIRE

    Varelasantibanez, C

    1992-01-01

    Une stratégie de repeuplement du "loco" Concholepas concholepas (B) est développée dans le sud du Chili à partir de résultats obtenus au laboratoire sur la reproduction et la croissance de ce mollusque. Les reproducteurs sont conservés au laboratoire pendant toute l'année et l'émission de capsules ovigères peut être provoquée au cours de toute cette période. Les capsules sont ensuite transférées dans le milieu naturel où a lieu l'éclosion. Par ailleurs, des juvéniles recrutés dans le milie...

  18. effet du potassium et du deficit hydrique modere sur la transpiration ...

    African Journals Online (AJOL)

    AISA

    2Université de Cocody-Abidjan, Laboratoire de Physiologie et Pathologie Végétales, UFR Biosciences, 22 B.P. 582. Abidjan 22, Côte d'Ivoire. 3CIRAD-CP, TA 80/01, 34398 Montpellier cedex 5. RESUME. L'importance relative des ions K+ et Cl- dans la tolérance du palmier à la sécheresse n'est pas complètement.

  19. TABLE DES MATIÈRES 1.À propos du CRDI et du domaine de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Marie-Isabelle Beyer

    15 déc. 2014 ... Modalités de l'accord de subvention type du CRDI. 11 ... En partenariat avec le Department for International Development .... Les effets que la structure de la croissance a sur l'autonomisation économique des ..... Le CRDI a conclu un accord général de coopération scientifique et technique avec certains.

  20. l'algerie, du transfert de technologie a l'economie du savoir

    African Journals Online (AJOL)

    Abdelkader DJEFLAT

    sphère académique et l'entreprise, ni négocié correctement par la sphère de la ... La stratégie d'import-substitution poursuivie et les politiques mises en ...... formation adéquate a été à l'origine du bas niveau de recrutement des diplômés et de ...

  1. Accroissement de la compétitivité du Kenya dans l'économie du ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Pour répondre à la demande d'une participation plus active au développement, les universités doivent entretenir des relations plus étroites avec l'industrie et un vaste éventail d'acteurs sociaux. Vision 2030, le plan directeur du Kenya en matière de développement, fait des universités des acteurs de premier plan dans le ...

  2. CALCUL DU SPECTRE DE REFLEXION DU MULTICOUCHE Ni/C DANS LE DOMAINE DES RAYONS X

    Directory of Open Access Journals (Sweden)

    A MEDDOUR

    2000-12-01

    Full Text Available Le pouvoir réflecteur d’un dioptre quelconque dans le domaine des rayons X est trop faible, mais il est toujours possible de choisir des systèmes pouvant présenter un pic de réflexion d’intensité importante autour d’une incidence caractéristique du matériau. Ce dernier est un multicouche, composé de deux couches déposées en sandwich.                 Nous avons élaboré un programme qui permet de calculer la réflexion d’un tel matériau en suivant la méthode d’Abelès dans laquelle une couche mince est représentée par une matrice carrée contenant toutes les informations nécessaires pour le calcul de la réflexion. Ce programme tient compte aussi des rugosités aux interfaces du multicouche, vue leur importante influence sur l’intensité du pic apparaissant sur le spectre de réflexion.                 L’application du programme au multicouche Ni/C a montré  l’existence d’un pic centré autour de 31.32°. Son intensité est sensible au nombre de périodes dans le multicouche, aux épaisseurs des couches minces de Ni et de C et à la taille des rugosités des interfaces Ni/C et C/Ni.

  3. Lettre ouverte au Président du Conseil du CERN

    CERN Document Server

    Association du personnel

    2010-01-01

    Genève, le 1er février 2010 Monsieur le Président, Les membres de la Caisse de pensions, actifs et pensionnés, sont à la fois très inquiets et indignés par la manière avec laquelle le Conseil traite la question, devenue alarmante, de l’équilibre de la Caisse. Dès 2004 en effet, l’étude actuarielle avait alerté le Conseil au sujet du déficit technique du régime et de l’insuffisance du financement de son plan de prestations. Le Conseil s’est alors contenté de mettre en place un mécanisme de sous indexation des pensions – arbitraire et discriminatoire dans la mesure où il ne fait appel qu’à la solidarité des pensionnés – et de décider une augmentation minime des contributions à la Caisse, une mesurette ...

  4. Proudhon, science ou métaphysique du travail

    OpenAIRE

    Lecerf , Eric

    2008-01-01

    La philosophie de Proudhon, même si elle trouve son concept essentiel dans la justice, est intégralement une philosophie du travail, non pas que le travail en constitue l'objet unique, mais car c'est en lui que les tensions du réel sont concrètement identifiables. C'est dans sa critique que l'agir humain se donne comme émancipation et/ou aliénation, autrement dit que la dialectique acquiert toute sa justification. La philosophie du travail de Proudhon donnera lieu à deux lectures opposées : c...

  5. Brain stem hypoplasia associated with Cri-du-Chat syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jin Ho; Lee, Ha Young; Lim, Myung Kwan; Kim, Mi Young; Kang, Young Hye; Lee, Kyung Hee; Cho, Soon Gu [Dept. of Radiology, Inha University Hospital, Inha University School of Medicine, Incheon (Korea, Republic of)

    2013-12-15

    Cri-du-Chat syndrome, also called the 5p-syndrome, is a rare genetic abnormality, and only few cases have been reported on its brain MRI findings. We describe the magnetic resonance imaging findings of a 1-year-old girl with Cri-du-Chat syndrome who showed brain stem hypoplasia, particularly in the pons, with normal cerebellum and diffuse hypoplasia of the cerebral hemispheres. We suggest that Cri-du-Chat syndrome chould be suspected in children with brain stem hypoplasia, particularly for those with high-pitched cries.

  6. Business plan pour une application Smartphone : du concept au lancement

    OpenAIRE

    Vriamont, Gilles

    2015-01-01

    Création d'une application mobile pour Smartphone. Description théorique concernant la rédaction d'un business plan dans une première partie suivi d'une description théorique des caractéristiques des applications mobiles. Dans une seconde partie, analyse de l'industrie des Smartphones et des applications mobiles suivi de la partie pratique et du développement du produit, partant de la description du produit jusqu'à l'analyse des coûts. Master [120] en Ingénieur de gestion, Université catho...

  7. Compounds Labelled with Low-Energy Gamma-Ray Emitters for Medical Isotope Scanning; Gammagraphie au Moyen de Composes Marques avec des Emetteurs Gamma de Faible Energie; Soedineniya, ispol'zuemye pri meditsinskom izotopnom skennirovanii, mechennye s pomoshch'yu gamma-izluchatelej nizkoj ehnergii; Compuestos Marcados con Emisores Gamma de Baja Energia para la Exploracion Medica Mediante Isotopos

    Energy Technology Data Exchange (ETDEWEB)

    Scheer, K. E.; Zum Winkel, K.; Georgi, M. [Czerny-Krankenhaus der Universitat Heidelberg, Federal Republic of Germany (Germany)

    1964-10-15

    detecter de petites lesions. 2. L'absorption du rayonnement par les tissues limite la profondeur a laquelle les lesions sont 'visibles'. Dans de grands organes comme le foie, on evite la superposition des rayonnements provenant de la partie posterieure de l'organe, d'ou une meilleure detection des lesions superficielles. Le plus important emetteur gamma de faible energie est l'iode-125. Pour l'exploration de la thyroiede on l'utilise sous forme d'iodure. Pour le foie, le rose bengale marque avec {sup 125}I convient parfaitement, mais on peut aussi utiliser de l'albumine alteree par la chaleur et marquee avec {sup 125}I. Pour le rein, on a constate que l'hippuran marque avec {sup 125}I donne de bons resultats en injection intra-musculaire, si on le melange a de l'hyaluronidase pour assurer un niveau uniforme de radioactivite dans cet organe. Un autre emetteur gamma de faible energie tres utile en gammagraphie est le mercure-197, qui peut etre utilise sous forme de chlorure pour l'exploration du rein et de la rate. On doit prendre des precautions speciales pour eviter la superposition de ces organes. On obtient un meilleur scintigramme avec de la neo- hydrine marquee avec {sup 197}Hg; ce produit peut servir aussi a localiser les tumeurs du cerveau. Les auteurs donnent des details sur des cas typiques d'exploration de tumeurs de la thyroiede, du foie, de la rate, du rein et du cerveau, d'une part avec des emetteurs gamma de faible energie et d'autre part avec des nucleides et des composes classiques; ils comparent les resultats obtenus. (author) [Spanish] Los emisores gamma de baja energia presentan ventajas especiales para la exploracion medica por centelleografia. He aquilas razonest . 1. El blindaje de plomo de los colimadores es mucho mas eficaz. Por tanto, pueden utilizarse colimadores enfocados con canales de tabiques delgados, lo que da un mayor grado de resolucion geometrica y permite, por consiguiente, detectar lesiones'mas pequenas. 2. La absorcion de la radiacion

  8. Activity report 2015 Commission Perspectives du Reseau

    International Nuclear Information System (INIS)

    Ricour, Olivia

    2016-01-01

    This document contains the activity report for 2015 of the Commission Perspectives du Reseau which has been set up by RTE to be the main body for organising a dialogue with all the actors of the energy sector and civil society about challenges and stakes of the electric power system on the medium and on the long term. It describes how this body aims at sharing knowledge and expertise of all stakeholders (publications, European platform for data transparency), at being a place for debating and enriching the understanding of tomorrow's important stakes for the power system (discussion of the issue of greenhouse gas emissions with an analysis of the impact of the CO 2 price signal on emissions by the European electricity system and results of the e-Highway 2050 European project). The road-map of the Commission works for 2016 is provided, as well as a list of members

  9. Chronologie politique du Yémen. 2002

    Directory of Open Access Journals (Sweden)

    Stéphane Levaux

    2002-04-01

    Full Text Available photo © François Burgat Politique Intérieure Janvier-février 06 janvier : Dix chefs tribaux des provinces de Ma'rib, de Shabwa et du Jawf, provinces dont l'importance politique va croissant en raison des tensions sécuritaires, affirment leur soutien au Président `Alî `Abd Allâh /Sâli/h dans sa campagne antiterroriste. 14 janvier : L'ambassade américaine reçoit des menaces et ferme son service consulaire. 15 janvier : Amnistie et retour d'exil de Sâlim /Sâli/h Mu/hammad, ancien dirig...

  10. La crise du vivre-ensemble

    DEFF Research Database (Denmark)

    Schultz, Nils Voisin

    2014-01-01

    Cet article examine les caractères idéologique et affectif de deux essais écrits respectivement par Alain Finkielkraut et Richard Millet sur la crise actuelle du vivre-ensemble en France. Les deux penseurs critiquent la société multiculturelle, mais alors que pour Finkielkraut cette société est une...... chance pour la France à condition que le dialogue interculturel soit renforcé et que l’idée d’une culture française y garde sa place, elle reste pour Millet une impossibilité. L’enjeu de l’analyse est de dévoiler la capacité des discours à générer par l’affectivité une peur capable d’intensifier l’argumentation...

  11. Elevage intensif du loup Dicentrarchus labrax

    OpenAIRE

    Coves, Denis; Gasset, Eric

    1993-01-01

    Cet article fait le point sue les coûts de production directs relatifs à différentes méthodes d'élevage intensif du loup (Dicentrarchus labrax). Il s'appuie sur des résultats zootechniques obtenus dans l'unité de démonstration à grande échelle de notre laboratoire. Par rapport à un système de production en circuit ouvert, le recyclage de l'eau permet de diviser par 2.2 les charges directes de production. Si les proies vivantes sont précédemment remplacées par une microparticule efficace, ces ...

  12. evaluation du nouveau ne par cesarienne

    OpenAIRE

    MERAD, Atif Djelloul; BOUARFA, Wahiba

    2014-01-01

    L’étude rétrospective des dossiers montre un recueil des données anamnestiques peu satisfaisant. L’anamnèse reste l’élément essentiel qui permet de faire le point sur l’enfant nouveau-né adressé pour soins appropriés, elle doit retracer l’histoire de la grossesse jusqu’à l’accouchement. L’étude du profil de nos patientes montre que La césarienne concerne particulièrement les primipares qui représentent plus de la moitié de nos femmes. Le risque de césarienne augmente statistiquement lorsqu...

  13. [Development of rapid setting-drying device for herbarium specimens and its application in survey of Chinese materia medica resources in Anhui].

    Science.gov (United States)

    Zheng, Han; Xu, Tao; Li, Chuan-Run; Sun, Xiao-Mei; Xiang, Long; Zhao, Wei-Bo; Liu, He-Ling; Zhou, Jian-Li; Yang, Qing-Shan; Peng, Dai-Yin

    2016-07-01

    Herbarium specimens are the basis for the plant classification and indispensable media in teaching, scientific research and resources investigation. They have also played an important role in identifying and producing traditional Chinese medicine. High-quality herbarium specimens shall meet high requirements for integrity, smoothness, color and fabricating efficiency. Therefore, we designed a rapid setting and drying device for herbarium specimens, which could make the herbarium specimens smooth, colorful and not easy to mildew. In this paper, we pointed out the deficiency of traditional methods in making herbarium specimens, and introduced the structure and working principle of the device. Besides, we also discussed the effect of the device in setting and drying herbarium specimens and its application in the fourth national survey of the Chinese material medica resources (CMMR) in Anhui province. As a result, the device provides new ideas for producing herbarium specimens, with a reasonable design, good uniformity, high efficiency, safety and portability, and so is worthy of promotion and application in the national survey of CMMR. Copyright© by the Chinese Pharmaceutical Association.

  14. Medical response guide for the initial phase of a radiological emergency; Guia para la respuesta medica en la fase inicial de una emergencia radiologica

    Energy Technology Data Exchange (ETDEWEB)

    Vazquez, Marina A; Perez, Maria del R

    2007-07-01

    In case of a sanitary emergency, the local community and its health care system are the first aid providers. Therefore, preparedness through education and training programs would allow emergency systems to provide an appropriate first medical response. The main objective of this guide is to give basic guidelines for the medical response management after situations involving radioactive materials, in an easy and simple way. The information contained in this guide is addressed to health care personnel of any local assistance center. (author) [Spanish] Las emergencias que afecten a un numero importante de personas y que tengan como protagonistas agentes 'no convencionales' como lo son las radiaciones ionizantes, deben ser abordadas mediante la implementacion de programas sanitarios especiales. En una situacion de emergencia, generalmente los primeros en proporcionar la ayuda, son la comunidad local y su sistema de salud. Por ello la preparacion previa local, a traves de la capacitacion y el entrenamiento permitira brindar una respuesta inicial adecuada que se articule con un sistema de respuesta en emergencias escalonado y de complejidad creciente. Esto requiere la participacion de las autoridades de salud en cada uno de los niveles de atencion, asi como apoyo de otros sectores para desarrollar sus planes de preparacion y respuesta. La presente guia, como instrumento de capacitacion, tiene como objetivo primario brindar las herramientas basicas para el manejo de la respuesta medica en una situacion de emergencia que involucre material radiactivo, en un lenguaje claro y sencillo, dirigida al personal de salud de todos los centros asistenciales locales. (autor)

  15. Alternativas de medicação intracanal em casos de necrose pulpar com lesão periapical = Intracanal medication indicated for pulpal necrosis with apical osteites

    Directory of Open Access Journals (Sweden)

    Fachin, Elaine Vianna Freitas

    2006-01-01

    Full Text Available Trata-se de estudo in vivo em pacientes portadores de dentes monorradiculares apresentando necrose pulpar com lesão periapical. O objetivo foi avaliar radiograficamente a efetividade de 4 diferentes curativos de demora (PMCC, gel de clorexidina 2%, pasta de hidróxido de cálcio e hipoclorito de sódio1%. O tratamento endodôntico foi padronizado em todos os elementos através da técnica escalonada e irrigação com hipoclorito de sódio 1%. Para a medicação intracanal, os pacientes foram separados aleatoriamente em 4 grupos que receberam um dos medicamentos listados. Após 7 dias, os canais foram obturados e submetidos a controle radiográfico aos 3, 6 e 9 meses em que se mediu com precisão a diminuição do diâmetro radiolúcido apical. Os resultados mais satisfatórios ocorreram após o uso do PMCC, seguido pelo hidróxido de cálcio, clorexidina 2% e, por último, hipoclorito de sódio 1%

  16. Ameliorating effects of traditional Chinese medicine preparation, Chinese materia medica and active compounds on ischemia/reperfusion-induced cerebral microcirculatory disturbances and neuron damage

    Science.gov (United States)

    Sun, Kai; Fan, Jingyu; Han, Jingyan

    2015-01-01

    Ischemic stroke and ischemia/reperfusion (I/R) injury induced by thrombolytic therapy are conditions with high mortality and serious long-term physical and cognitive disabilities. They have a major impact on global public health. These disorders are associated with multiple insults to the cerebral microcirculation, including reactive oxygen species (ROS) overproduction, leukocyte adhesion and infiltration, brain blood barrier (BBB) disruption, and capillary hypoperfusion, ultimately resulting in tissue edema, hemorrhage, brain injury and delayed neuron damage. Traditional Chinese medicine (TCM) has been used in China, Korea, Japan and other Asian countries for treatment of a wide range of diseases. In China, the usage of compound TCM preparation to treat cerebrovascular diseases dates back to the Han Dynasty. Even thousands of years earlier, the medical formulary recorded many classical prescriptions for treating cerebral I/R-related diseases. This review summarizes current information and underlying mechanisms regarding the ameliorating effects of compound TCM preparation, Chinese materia medica, and active components on I/R-induced cerebral microcirculatory disturbances, brain injury and neuron damage. PMID:26579420

  17. [Textual research on Guang dong xin yu (New Sayings of Guangdong) quoted in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica].

    Science.gov (United States)

    Zhang, Ruixian; Zhang, Wei; Li, Jian; Liang, Fei

    2014-05-01

    Altogether 15 terms for Guang dong xin yu (New Sayings of Guangdong) were used in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica), including Yue yu (Cantonese sayings), Chong yu (Sayings from Insect Drug), Jie yu (Sayings from Crustacean Drug), Xin yu (New Sayings), Yue hai xiang yu (Fragrant Sayings from Cantonese Region), Yue zhi mu yu (Sayings from Plants in Cantonese Annals), Guang dong suo yu (Trivial Sayings from Guangdong), Yue shan lu (Records of Cantonese Mountains), Yue lu (Cantonese Records), Jiao guang lu (Joint Guangdong Records), Yue cao zhi (Records of Cantonese Grasses), Guang guo lu (Records of Guangdong Fruits), Nan yue suo ji (Trivial Records of Southern Canton), Guang zhi (Guangdong Records), Yue zhi (Cantonese Records) etc. dealing with 57 sorts of drugs (with individual overlapping ones), the author of Xin yu was Qu Dajun, a surviving fogy of the Ming Dynasty actively involved in the activities to restore the old dynasty and resist the Qing Dynasty, and was persecuted in the literary inquisition in which his works were burnt so that Zhao Xuemin, when quoting his texts, had to go in a roundabout way.

  18. Adaptação multicêntrica do guia para a gestão autônoma da medicação

    Directory of Open Access Journals (Sweden)

    Rosana Teresa Onocko Campos

    2012-12-01

    Full Text Available O uso crescente de psicofármacos e o baixo empowerment dos usuários mostram-se críticos à qualificação da assistência em Saúde Mental no Brasil. Este estudo, abrangendo três cidades brasileiras, objetivou a elaboração do Guia Brasileiro da Gestão Autônoma da Medicação (GGAM-BR, com base na tradução e adaptação de guia desenvolvido no Canadá; e a avaliação dos efeitos do uso do GGAM-BR na formação de trabalhadores de saúde mental. Constituíram-se grupos de intervenção (GIs para compartilhamento das experiências com tratamento medicamentoso, a partir dos temas propostos no guia; e foram realizados grupos focais antes e após os GIs. Importantes mudanças em relação ao texto original do guia Canadense foram implementadas, levando em conta a realidade brasileira. Constatou-se que o GGAM-BR constitui estratégia potente de fomento à participação ativa dos usuários na gestão do tratamento e do serviço, incidindo positivamente na formação de trabalhadores.

  19. Entretiens sur la multitude du monde

    CERN Document Server

    Damour, Thibault

    2014-01-01

    L'un est un écrivain et un scénariste célèbre. L'autre est un physicien et un chercheur mondialement connu. Une même interrogation les porte. Comment penser le monde après un siècle de bouleversements scientifiques ? Jean- Claude Carrière et Thibault Damour nous entraînent ici dans un dialogue lumineux, qui met l'esprit au défi de lui- même et où la clarté rivalise avec le gai savoir. La matière éternelle, l'espace et le temps absolus, l 'unique réalité : en ce début de troisième millénaire, toutes ces grandes notions du passé n'ont plus qu'une valeur d'illu- sions. Il n'y a plus d'histoire prédéterminée, inexorable, li- vrée à des forces mécaniques. L'univers se révèle léger, instable, multiple dans la superposition d'une infinité d'his- toires possibles dont nous ne percevons qu'un mince fais- ceau. C'est à la découverte de cette multitude du monde, laissant loin derrière les récits de science-fiction, que nous invitent Jean-Claude Carrière et Thibault Damour. Un voyage p...

  20. Validação da Prescrição Oncológica: o papel do farmacêutico na prevenção de erros de medicação

    Directory of Open Access Journals (Sweden)

    Livia Oliboni

    2009-09-01

    Full Text Available Erros de medicação são constantemente relatados na literatura médico-científica. Há casos clínicos em que a administração inadequada de doses altas de alguns citostáticos tem como consequência a toxicidade grave e a morte do paciente. As não conformidades presentes nas prescrições aos pacientes oncológicos podem ser catastróficas em função da estreita margem terapêutica dos medicamentos antineoplásicos. Prevenir erros de medicação torna-se uma prioridade na melhora do processo farmacoterapêutico em pacientes da oncologia. A multidisciplinaridade é um fator essencial de alerta aos erros de medicação de antineoplásicos e às maneiras de preveni-los Os farmacêuticos e todos os profissionais que constituem uma equipe multidisciplinar de saúde contribuem para garantia do uso seguro dos medicamentos, o que auxilia no aprimoramento de uma assistência qualificada. Para isso, além das atividades já bem estabelecidas, esses profissionais devem (i implantar um sistema de validação farmacêutica bem como (ii estabelecer um sistema de verificação da prescrição médica, o qual consiste em diferentes etapas. O objetivo dessa revisão é relatar a validação da prescrição médica, considerando-se os erros de medicação na quimioterapia e o papel do farmacêutico na prevenção desses erros. São medidas que visam a melhorar a qualidade da assistência prestada aos pacientes oncológicos.

  1. Impact socio professionnel de la libération chirurgicale du syndrome du canal carpien

    Science.gov (United States)

    Kraiem, Aouatef Mahfoudh; Hnia, Hajer; Bouzgarrou, Lamia; Henchi, Mohamed Adnène; Khalfallah, Taoufik

    2016-01-01

    L’objectif de notre travail était d’étudier les conséquences socioprofessionnelles d’une libération chirurgicale du SCC. Il s’agit d’une étude transversale portant sur les sujets opérés pour un SCC d’origine professionnelle ; recensés dans le Service de Médecine de Travail et de Pathologies Professionnelles au CHU Tahar Sfar de Mahdia en Tunisie sur une période de 8 ans allant du 1 Janvier 2006 au mois Décembre 2013. Le recueil des données s’est basé sur une fiche d’enquête, portant sur la description des caractéristiques socioprofessionnelles, médicales, et sur le devenir professionnel des participants. Pour étudier les contraintes psychosociales au travail, nous avons adopté le questionnaire de Karasek. La durée d’arrêt de travail après libération chirurgicale du SCC était significativement liée à l’existence d’autres troubles musculo-squelettiques autre que le SCC, la déclaration du SCC en maladie professionnelle et à l’ancienneté professionnelle des salariés. Quant au devenir professionnel des salariés opérés, 50,7% ont gardé le même poste, 15,3% ont bénéficié d’un aménagement de poste et 33,8% ont bénéficié d’un changement de poste dans la même entreprise. Le devenir professionnel de ces salariés était corrélé à leurs qualifications professionnelles et au type de l’atteinte sensitive et/ou motrice du nerf médian à l’EMG. Un certain nombre de facteurs non lésionnels déterminaient la durée de l’arrêt de travail, alors que le devenir professionnel des opérés pour SCC dépendait essentiellement de leurs qualifications professionnelles et des données de l’électromyogramme. Il est certain que des travaux beaucoup plus larges permettraient d’affiner encore ces résultats. PMID:27800089

  2. Politique de gestion de l'habitat du poisson du Ministère des pêches et des océans

    National Research Council Canada - National Science Library

    1986-01-01

    Le present document enonce la politique, les objectifs et les strategies du Ministere des Peches et des Oceans pour la gestion de l'habitat du poisson dont dependent les peches canadiennes en eaux douces et marines...

  3. Archéologie d’un parasite du cheval

    OpenAIRE

    Dufour, Benjamin; Bailly, Matthieu Le

    2017-01-01

    Oxyuris equi, l’oxyure du cheval, est un vers parasite spécifique des équidés régulièrement mis en évidence lors des études paléoparasitologiques. Nous proposons ici une synthèse originale entre les mentions de ce parasite connues dans la bibliographie et les textes anciens, avec des données inédites issues de nos recherches en paléoparasitologie. Cette compilation des données montre que la plus ancienne observation de l’oxyure du cheval date du milieu du Ier millénaire avant notre ère en Asi...

  4. Echographie devant une metrorragie du premier trimestre de ...

    African Journals Online (AJOL)

    Echographie devant une metrorragie du premier trimestre de grossesse sur uterus bicorne a issue favorable. Vaginal bleeding in a pregnant woman with a bicornuate uterus, ultrasound finding and favourable outcome.

  5. Ottawa exprime son soutien lors des projections du documentaire ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    22 mars 2017 ... Les récentes projections à Ottawa du film primé Little Gandhi: The lost truth of the Syrian uprising ont été chaleureusement accueillies tant par les parlementaires que par le public.

  6. Duši alla sauna / Margit Aedla

    Index Scriptorium Estoniae

    Aedla, Margit, 1970-

    2007-01-01

    Duraviti multifunktsionaalne värviline duširuum. Electroluxi Design Lab'07 konkursi finalisti Joao Diego Schimansky Fog Shower (ududuš). Väiksematesse kodudesse sobiv Muoto mobiilne aurusaunatool Muoto-Steam Deluxe

  7. Sibelius: Luonnotar. Chevauchee nocturne et lever du soleil / Pierre Gervasoni

    Index Scriptorium Estoniae

    Gervasoni, Pierre

    1996-01-01

    Uuest heliplaadist "Sibelius: Luonnotar. Chevauchee nocturne et lever du soleil. 4 Legendes. Orchestre Philharmonique Royal de Stockholm, Paavo Järvi. Virgin Classics 545 213-2 (CD:167F). 1996. TT: 1h 13'22"

  8. Stravinsky, Igor: Le Sacre du Printemps / Pierre-E. Barbier

    Index Scriptorium Estoniae

    Barbier, Pierre-E.

    1996-01-01

    Uuest heliplaadist "Stravinsky, Igor: Le Sacre du Printemps. Requiem Canticles. Canticum sacrum. Variations sur un choral de Bach. Orchestre de la Suisse Romande, Neeme Järvi" Chandos CHAN 9 408, distribution Media 7 (SD:160F)

  9. Emilie du Châtelet between Leibniz and Newton

    CERN Document Server

    Hagengruber, Ruth

    2012-01-01

    This book describes Emilie du Chatelet known as "Emilia Newtonmania", and her innovative and outstanding position within the controversy between Newton and Leibniz, one of the fundamental scientific discourses of her time.

  10. Sodium purification in Rapsodie; La purification du sodium a Rapsodie

    Energy Technology Data Exchange (ETDEWEB)

    Giraud, B [Commissariat a l' Energie Atomique, Dir. des Piles Atomiques, Cadarache (France). Centre d' Etudes Nucleaires

    1968-07-01

    This report is one of a series of publications presenting the main results of tests carried out during the start-up of the first french fast neutron reactor: Rapsodie. The article presents the sodium purification techniques used in the reactor cooling circuits both from the constructional point of view and with respect to results obtained during the first years working. (author) [French] Ce rapport fait partie d'une serie de publications presentant l'essentiel des resultats des essais effectues a l'occasion du demarrage du premier reacteur francais a neutrons rapides: RAPSODIE. Cet article expose les techniques de la purification du sodium utilise dans les circuits de refroidissement du reacteur tant au point de vue de leur realisation technologique, que des resultats obtenus pendant la premiere annee de fonctionnement. (auteur)

  11. Magic turtle dans le canton du Jura: concept marketing

    OpenAIRE

    Hauser, Magali; Perruchoud-Massy, Marie-Françoise

    2012-01-01

    Depuis juin 2009, Saint-Ursanne/Clos du Doubs est une région pilote du Projet Enjoy Switzerland/ASM ayant pour but d’intervenir sur le développement et la sensibilisation du tourisme dans la région. En parallèle, la Maison du Tourisme, entreprise proposant principalement des offres touristiques dans la région, a ouvert ses portes l’année dernière. Ces deux entités ont travaillé ensemble afin de développer une nouvelle offre touristique intitulée « Magic turtle ». Le Magic turtle, pensé par de...

  12. La microflore des sols du vignoble de Touraine

    Directory of Open Access Journals (Sweden)

    Claude Cuinier

    1975-12-01

    Full Text Available L'étude microbiologique des sols du vignoble porte sur trois années. Les déterminations quantitatives des bactéries, champignons, actinomycètes et des groupes fonctionnels des cycles de l'azote, du carbone et du soufre sont effectuées au cours de trois périodes du cycle végétatif de la vigne. Des variations saisonnières et annuelles sont observées. La microflore des sols viticoles est comparée à celle d'autres sols. Elle est au moins aussi riche et se distingue par son caractère plus aérobie. De grands écarts dans la composition microbiologique sont apparus entre des sols viticoles différant par leurs caractéristiques physiques et chimiques.

  13. Protéger les collectivités côtières du nord du Maroc | CRDI - Centre ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    3 févr. 2011 ... Élévation du niveau de la mer, ondes de tempête, inondations littorales : les ... Un plan d'action en matière de gestion intégrée du littoral et une nouvelle ... du territoire sans recourir à un guide de la dynamique du milieu côtier. ... local, et encore moins de contrôle sur les terres dont elles sont tributaires.

  14. Communication du Service juridique et du Département HR à l'attention des membres du personnel domiciliés en France

    CERN Multimedia

    HR Department

    2007-01-01

    Déclaration de revenus 2006 Les membres du personnel trouveront ci-après les informations nécessaires sur la manière de remplir la déclaration de revenus 2006, qui doit être retournée au plus tard le 31 mai 2007. Qui doit remplir la déclaration? Comment l'obtenir? Tous les membres du personnel1) domiciliés en France2), qu'ils soient ou non de nationalité française, doivent remplir la déclaration de revenus 2006 sur la base des présentes instructions et la renvoyer signée, au plus tard le 31 mai 2007, au centre des impôts de leur domicile. Les membres du personnel devraient recevoir la déclaration de revenus 2006 fin avril - début mai. Ceux qui ne la recevraient pas directement devront la retirer au centre des impôts, à la trésorerie ou à la mairie de leur domicile ou bien encore la télécharger sur le site internet du Ministère des Finances (www.finances.gouv.fr). Comment remplir la déclaration Les membres du personnel doivent remplir la DECLARATION PAPIER uniquement. Dé...

  15. Du Mal-être au votre extrême

    OpenAIRE

    Gethin,, Amory; Jenmana,, Thanasak

    2017-01-01

    Note d'analyse de l'Observatoire du Bien-être du CEPREMAP; The rise of populism and the failure of traditional parties during the 2017 French presidential election calls to question the relevance of traditional determinants of voting. Given the difficult economic context associated with François Hollande’s term, to what extent has the increasing pessimism in France contributed towards anti-establishment voting?Available surveys reveal two remarkable phenomena. The extremes, particularly the e...

  16. Le developpement olympique du kayak Africain : Anglophonie vs ...

    African Journals Online (AJOL)

    Si le kayak de slalom s'est développé récemment en Afrique (premier Championnat continental organisé en 2009), il a été médiatisé à la faveur de sa reconnaissance olympique. Mais quels sont les enjeux culturels du développement olympique du kayak en Afrique francophone ? Comment cette activité a-t-elle pu ...

  17. Donner aux travailleurs du sexe les moyens de consigner les ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Dans la plupart des sociétés, le travail du sexe est fortement stigmatisé, et ceux qui le pratiquent sont en butte aux reproches, à la désapprobation et à la discrimination. Par conséquent, la violence faite aux travailleurs du sexe se voit peu, et dans certains contextes, elle est même tolérée. On dispose donc de très peu de ...

  18. Reproduction du programme MamaToto en Tanzanie rurale ((ISMEA)

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le nouvel engagement du gouvernement de la Tanzanie visant à améliorer le bien-être des mères et des enfants a besoin de données probantes appuyant la création de ... L'équipe du projet mobilisera les responsables de district, renforcera les services des établissements et précisera le rôle des travailleurs en santé ...

  19. L'Afrique, nouvel Eldorado du commerce | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    5 déc. 2013 ... Il est directeur du Perimeter Institute for Theoretical Physics, où il est également titulaire de la chaire Mike and Ophelia Lazaridis Niels Bohr. Thierry Zomahoun, M.B.A., M.Ph., est directeur général de l'AIMS Next Einstein Initiative (AIMS-NEI) et directeur du secrétariat mondial d'AIMS. Cet article a été publié ...

  20. American Circus Re-Invented: Queering Cirque Du Soleil

    OpenAIRE

    Johnson Jr., Michael

    2011-01-01

    This research examines Zumanity: The Sensual Side of Cirque Du Soleil. Written and directed by Dominic Champagne and René Richard Cyr, this performance departs from the other Cirque productions by incorporating a sexual theme that conceptually reflects a part burlesque, part cabaret performance. Cirque Du Soleil presents an opportunity to ask some important and challenging questions like: Is Zumanity indicative of a change in how nouveau cirque or the contemporary circus movement presents mas...

  1. Le marché sociolinguistique contemporain du Maroc

    NARCIS (Netherlands)

    de Ruiter, A.C.J.; Ziamari, Karima

    2014-01-01

    Au Maroc, les langues sont l’objet des polémiques les plus passionnées. Ce livre s’inscrit ainsi dans la continuité du débat concernant les politiques linguistiques adoptées et met à jour les évolutions récentes du marché sociolinguistique après l’adoption de la nouvelle constitution, approuvée par

  2. Etude Du Comportement Dynamique D'un Systeme De Pompage ...

    African Journals Online (AJOL)

    SIMULINK le comportement dynamique d'un système de pompage composé d'un générateur photovoltaïque, d'un onduleur, d'un moteur à induction et d'une pompe centrifuge. Le modèle global du système est bouclé : la sortie tension du GPV est ...

  3. L'Afrique, nouvel Eldorado du commerce | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    5 déc. 2013 ... Il est directeur du Perimeter Institute for Theoretical Physics, où il est également titulaire de la chaire Mike and Ophelia Lazaridis Niels Bohr. Thierry Zomahoun, M.B.A., M.Ph., est directeur général de l'AIMS Next Einstein Initiative (AIMS-NEI) et directeur du secrétariat mondial d'AIMS. Cet article a été publié ...

  4. Gestion du Centre | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le Comité de gestion du Centre (CGC) est composé des membres de la haute direction du CRDI, notamment les directeurs de nos quatre bureaux régionaux et de nos principaux secteurs de programme. Le CGC travaille en collaboration avec le président afin de soutenir la recherche pour le développement, lui fournissant ...

  5. Removal of radiostrontium from man; Elimination du radiostrontium de l'organisme humain; Vyvedenie radioaktivnogo strontsiya iz organizma cheloveka; Eliminacion del radioestroncio por el organismo humano

    Energy Technology Data Exchange (ETDEWEB)

    Spencer, H. [Edward Hines, Jr. Hospital Hines, IL (United States)

    1963-02-15

    Studies of the metabolism of radiostrontium were carried out in man under controlled metabolic and dietary conditions. The relatively short-lived radioisotope Sr{sup 85} was used as the tracer. Single tracer doses of Sr{sup 85} were administered intravenously and orally and the plasma levels and urinary and faecal excretions were determined. The main pathway of Sr{sup 85} excretion was found to be via the kidney irrespective of the route of administration of the tracer. An average of 20% of the orally administered dose was absorbed from the intestine and approximately 50% of the absorbed dose was excreted in urine in 12 d by a large number of persons, Studies in which tracer doses of Sr{sup 85} and Ca{sup 45} were given simultaneously by the oral route indicated the preference of the body for Ca{sup 45} absorption and for Sr{sup 85} excretion, the Ca{sup 45}/Sr{sup 85} absorption ratio being 2.6:1. Sr{sup 85} studies carried out during low and high calcium intake in the same persons revealed that the high calcium intake did not lead to any significant change of Sr{sup 85} absorption in most of the persons studied. Since the urinary Sr{sup 85} excretion was found to parallel the urinary calcium excretion, enhancement of urinary calcium was induced by different agents, which increased the calciuria. Intravenously infused stable calcium and strontium, orally administered ammonium chloride given singly or in combination with intravenously infused calcium and certain chelating agents were effective in removing radiostrontium from man as late as two to four weeks after the injection of the tracer. Also, Sr{sup 90} balance studies were carried out in 12 young normal volunteers. No radioisotope was given in this study. The results obtained in Sr{sup 90} studies were similar to those obtained with Sr{sup 85}. (author) [French] Le metabolisme du radiostrontium dans l'organisme humain a ete etudie dans des conditions controlees de metabolisme et de regime alimentaire; le

  6. The biokinetics of uranium migrating from embedded DU fragments

    International Nuclear Information System (INIS)

    Leggett, R.W.; Pellmar, T.C.

    2003-01-01

    Military uses of depleted uranium (DU) munitions have resulted in casualties with embedded DU fragments. Assessment of radiological or chemical health risks from these fragments requires a model relating urinary U to the rate of migration of U from the fragments, and its accumulation in systemic tissues. A detailed biokinetic model for U has been published by the International Commission on Radiological Protection (ICRP), but its applicability to U migrating from embedded DU fragments is uncertain. Recently, ) conducted a study at the Armed Forces Radiobiology Research Institute (AFRRI) on the redistribution and toxicology of U in rats with implanted DU pellets, simulating embedded fragments. This paper compares the biokinetic data from that study with the behavior of commonly studied forms of U in rats (e.g., intravenously injected U nitrate). The comparisons indicate that the biokinetics of U migrating from embedded DU is similar to that of commonly studied forms of U with regard to long-term accumulation in kidneys, bone, and liver. The results provide limited support for the application of the ICRP's model to persons with embedded DU fragments. Additional information is needed with regard to the short-term behavior of migrating U and its accumulation in lymph nodes, brain, testicles, and other infrequently studied U repositories

  7. Etude de l'origine du citronellol dans les vins

    Directory of Open Access Journals (Sweden)

    Isabelle Dugelay

    1992-09-01

    Full Text Available La formation du citronellol à partir du géraniol et du nérol au cours de la fermentation de moûts synthétiques et naturels de raisin par différentes souches de levures a été étudiée. Le géraniol et le nérol sont transformés en citronellol par la levure, ceci de façon plus marquée avec le géraniol. La quantité de citronellol formé dépend de la souche de levure utilisée. D'autres monoterpènes, comme les acétates de géranyle et de néryle et l'α-terpinéol, sont aussi formés au cours de la fermentation. La préparation enzymatique utilisée n'a pas montré d'activités réductases vis-à-vis du géraniol et du nérol pour former du citronellol.

  8. L'avenir du Moyen-Orient et de l'Afrique du Nord passe par la ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    10 janv. 2013 ... Centre de recherches pour le développement international Gouvernement du Canada ... du Nord passe par la croissance partagée et l'économie de marché ... vivant en région éloignée aient un accès égal aux possibilités économiques. ... visant à trouver de nouveaux modes d'action pouvant contribuer au ...

  9. La violence dans les services sociaux: situation dans les services d'aide contrainte du canton du Jura

    OpenAIRE

    Durand, Loriane; Favre, Eliane

    2017-01-01

    Mon Travail de Bachelor a pour but premier de prendre connaissance de la situation de la violence dans les services d’aide contrainte du canton du Jura. La violence est-elle une réalité ? De quels types de violence s’agit-il ? Pourquoi cette violence, quelles en sont les raisons ? Cette violence augmente-t-elle le stress dans la profession d’assistant social ?

  10. Effets du barrage sur l'volution du trait de côte | Blivi | Journal de la ...

    African Journals Online (AJOL)

    Effets du barrage sur l'volution du trait de côte. A. Blivi. Abstract. (J. de la Recherche Scientifique de l'Université de Lomé, 2000, 4(1): 29-42). Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · http://dx.doi.org/10.4314/jrsul.v4i1.16996 · AJOL African Journals Online.

  11. La granitula de la Santa du Niolu

    Directory of Open Access Journals (Sweden)

    Davia Benedetti

    2012-01-01

    Full Text Available Abstract – IT   Quale modalità sociale fonda la pratica di una danza rituale pre-cristiana, la granitula, in occasione della festa annuale della Santa nel Niolo, in Corsica? Questa danza vi perdura nel quadro di un pellegrinaggio istituito sulla base di un racconto leggendario, in commemorazione della natività della Vergine. Essa è associata a una cerimonia religiosa e a una fiera. Consiste in una marcia a spirale a doppio senso, scandita da canti e condotta dai membri delle confraternite. La granitula ha rilievo nel campo etno-scenologico con la trasposizione corporea di immagini del labirinto, dell'origine e del sé. Simboleggia il corpo sociale corso e il suo senso d'appartenenza regionale e paesana. Coloro che la eseguono entrano in coesione con la comunità corsa. Fanno corpo con essa per proiettare nel vivere comune della società la loro assicurazione di uscita da ogni labirinto grazie a una prassi solidare, al rinserrare dei legami comunitari e a un adattamento identitario ai cambiamenti. Abstract – FR Quelle sociabilité fonde la pratique d’une danse rituelle antechrétienne, la granitula, lors de la fête annuelle de la Santa dans le Niolu, en Corse? Cette danse y perdure dans le cadre d’un pèlerinage établi sur un récit légendaire, en commémoration de la nativité de la Vierge. Elle est associée à une cérémonie religieuse catholique et à une foire. Elle consiste en une marche spiralée à double sens, scandée par des chants et exécutée par les membres des confréries. La granitula relève du champ de l’ethnoscénologie avec une mise en corps des figures du labyrinthe, de l’origine et du même. Elle symbolise le corps social corse et ses sentiments d’appartenance régionale et villageoise. Ses exécutants entrent en cohésion avec la communauté corse. Ils font corps avec elle pour projeter dans le vivre ensemble sociétal leur assurance de la sortie de tout labyrinthe par une pratique des solidarit

  12. Images du Mage, images pour le Mage

    Directory of Open Access Journals (Sweden)

    Daniel GREGORIO

    2007-01-01

    Full Text Available Les œuvres d’Alphonse X proposent diverses représentations du mage, qui en font, tour à tour, l’ennemi ou l’allié de la religion chrétienne. Il est vrai que parfois, comme le montre l’histoire de Simon le magicien, la pratique de la magie implique un commerce direct et néfaste avec les forces infernales. Néanmoins, les personnages de Merlin et des Rois Mages, tels qu’ils sont présentés par Alphonse X, démontrent que magie et religion peuvent cohabiter, à condition toutefois que le mage croit en la virginité de Marie et en l’Incarnation et que sa pratique magique soit bénéfique pour la communauté. Ce bénéfice requiert parfois la reconstruction de l’univers quotidien ; pour ce faire, le magicien doit savoir quand et comment utiliser des objets et des pentacles, qui lui permettront de soumettre les forces surnaturelles. Il doit donc posséder une connaissance approfondie du monde naturel et des esprits qui, conjuguée à sa foi religieuse, l’empêchera de tomber dans la démonolâtrie.Las obras alfonsíes proponen diversas aproximaciones al personaje del mago, generalmente considerado como un ser antagónico del hombre religioso. Es cierto que en algunas ocasiones, como ocurre con Simón el mago, la práctica de las artes mágicas significa un trato directo y nefasto con las fuerzas infernales. Sin embargo, personajes como Merlín o los Reyes Magos, tal y como los describe Alfonso X, subrayan una posible cohabitación entre magia y religión sin que la práctica de la una signifique la exclusión de la otra. Sólo hay que cumplir con dos condiciones : creer en la virginidad de María y que Dios se hizo hombre, y proporcionar a la comunidad un beneficio claro. Este beneficio requiere en ocasiones remodelar lo cotidiano, utilizando objetos y pentáculos, en circunstancias extremadamente determinadas, lo que implica un conocimiento exhaustivo tanto del mundo natural como del simbólico y de los espíritus. Es este

  13. Les dimensions émotionnelles du terrorisme

    Directory of Open Access Journals (Sweden)

    Benjamin Ducol

    2013-10-01

    Full Text Available Par une volonté louable de rompre avec des approches psychologisantes du phénomène terroriste dominantes au cours des années 1960-70, les recherches contemporaines en matière de terrorisme(s et de violence(s politique(s ont très largement mis l’emphase sur la figure du « terroriste » comme acteur rationnel et stratégique. Face aux limites des approches rationalistes de l’engagement radical qui envisagent de manière réductionniste les individus au travers d’un calcul rationnel univoque en terme de coûts et d’incitatifs à l’action, il nous apparaît important de réintégrer dans les réflexions théoriques sur les phénomènes terroristes, les émotions afin d’en interroger le rôle dans la production d’une trajectoire violente. Le présent article entend proposer à cet égard un bilan critique des travaux universitaires actuels autour de l’engagement terroriste et une réflexion théorique mettant en lumière les contours d’un futur agenda de recherche accordant une place plus importante aux ressorts émotionnels de la violence politique clandestine. Contemporary research on terrorism(s and political violence(s have largely put the emphasis on the figure of the "terrorist" as rational and strategic player, in a break with psychoanalytical approaches to terrorism that were dominant from the 1960-1970’s. Given the limitations of rationalist approaches to radical commitment, and considering how reductionist is the understanding of individual participation to terrorism related activities through a rational calculation framework in terms of costs and incentives to action, it is important to reintegrate in the theoretical reflections on terrorist phenomena how emotions can play a role in leading potential terrorists down a violent path. This paper presents a critical assessment of current academic work surrounding the issue of violent radicalization and involvement in terrorism, and engages in a theoretical debate

  14. El ensayo Ars Medica de John Locke, y la influencia de sus ideas médicas sobre la filosofía empirista

    Directory of Open Access Journals (Sweden)

    Sánchez González, Miguel Ángel

    2014-06-01

    Full Text Available John Locke’s essay Ars medica of 1669, is presented, analyzed and translated into Spanish. This essay shows the medical problems that prompted Locke´s philosophy and provides essential clues to understanding the motives, aims and characteristics of the empiricist`s theory of knowledge. Ideas originated in medicine that profoundly influenced subsequent Locke`s works were: 1 Trust in the perfectibility of science and elucidation of the role that philosophical thinking could play. 2 Rejection of knowledge deduced from principles, hypotheses or maxims. 3 Reliance on a «plain historical method» for the production of knowledge, which tried to register facts descriptively, while abandoning the study of ultimate causes. 4 Use of a three-part classification of the sciences that enthrones semiotics, medical science par excellence, and defines it as a mere knowledge of the signs of things, that is not intended to discern either essences or substances. Locke, in his epistemology, applies to all scientific knowledge the medical theory of the signs of illnesses. He envisions all possible science as a mere descriptive knowledge of signs; and thinks that knowledge is probabilistic, analogous and pragmatic.Se presenta, analiza y traduce por primera vez al castellano, el ensayo Ars Medica escrito por John Locke en 1669. Este ensayo muestra los problemas médicos que dieron origen al conjunto de la filosofía de Locke; y ofrece claves esenciales para comprender los motivos, las metas y los rasgos de la teoría del conocimiento empirista. Ideas originariamente médicas que tuvieron una repercusión directa en la obra posterior de Locke fueron: 1 Confianza en la perfectibilidad de la ciencia y elucidación del papel que la reflexión filosófica podía desempeñar en ello. 2 Rechazo del conocimiento deducido de principios, hipótesis o máximas. 3 El método «histórico simple» para edificar el conocimiento; que intentaba registrar los hechos descriptivamente

  15. Positron annihilation in solids: positronium diffusion; Annihilation du positon dans les solides diffusion du positonium

    Energy Technology Data Exchange (ETDEWEB)

    Paulin, R [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-04-01

    The existence of two slow components in life-time spectrum of positron annihilation in silicium, aluminium and alkaline-earth oxides powders is established. These two long mean-lives {approx_equal} 10{sup -9} s and {approx_equal} 10{sup -7} s result from annihilation, inside and outside the grains respectively, of ortho-positronium formed in defects present in ionic crystals investigated. Dynamic behaviour of Ps, so revealed, is analyzed in terms of diffusion in excellent agreement with experiment. Diffusion constants of the order of 10{sup -4} cm{sup 2} sec{sup -1} and mean path before annihilation from 50 to 300 Angstrom are measured. From 100 to 500 K the temperature influence upon diffusion process is effective only in SiO{sub 2} where activation energy is found about 10{sup -2} eV. The p-Ps zero point energy evaluated by angular correlation gives the order of magnitude for defects dimensions and diffusion mean-time. Finally, o-Ps behaviour in space between grains, where its interaction with atmospheric gases can be only detected, is analysed. (author) [French] Nous mettons en evidence l'existence de deux composantes lentes dans le spectre de temps de vie du positon avant annihilation dans des poudres d'oxydes alcalinoterreux d'alumine et de silice. Ces deux longues vies moyennes {approx_equal} 10{sup -9} s et {approx_equal} 10{sup -7} s resultent respectivement de l'annihilation a l'interieur et a l'exterieur des grains de l'ortho-positonium forme dans certains defauts presents dans les cristaux ioniques etudies. L'analyse des proprietes dynamiques du Ps ainsi revelees, est effectuee en termes de diffusion en excellent accord avec l'experience. Des constantes de diffusion de l'ordre de 10{sup -4} cm{sup 2} sec{sup -1} et des parcours moyens avant annihilation variant de 50 a 300 Angstrom sont ainsi mesures. Entre 100 et 500 K l'influence de la temperature sur le processus de diffusion n'est sensible que dans SiO{sub 2} ou l'energie d'activation est trouvee

  16. Bio-metric study of pig karyotype; Etude biometrique du caryotype du porc

    Energy Technology Data Exchange (ETDEWEB)

    Haag, J; Lacourly, N; Nizza, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-07-01

    This study has a twofold purpose, the former is to determine the swine karyotype as accurately as possible, the latter is to try and develop a method of automatic classification and to show its possibilities and limits. (authors) [French] Cette etude a un double objet: d'une part, de definir de la facon aussi precise que possible le caryotype du porc et d'autre part, de tenter une methode de classification automatique et d'en montrer les possibilites ainsi que les limites. (auteurs)

  17. A acetamida de pirrolidona como medicação auxiliar no tratamento da paralisia cerebral Pyrrolidone acetamide as an auxiliary drug in the treatment of cerebral palsy

    Directory of Open Access Journals (Sweden)

    Francisca Salete Pinheiro Chagas Ribeiro

    1976-06-01

    Full Text Available Vinte crianças, com diagnóstico de paralisia cerebral (PC e sob tratamento clássico, fisioterápico e pedagógico, receberam piracetam (acetamida de pirrolidona como medicação auxiliar. O objetivo foi melhorar os problemas de espasticidade, apredizagem, neurolabilidade, visando a um rendimento melhor do tratamento global da PC. O grupo medicado foi comparado com um grupo controle de 20 crianças que só eram objeto do tratamento habitual. A comparação mostrou resultados favoráveis no grupo medicado. A droga foi administrada na dose de 80 mg/kg/dia durante 10 semanas. Os critérios de avaliação dos resultados foram psicológicos, clínico, fisioterápico e pedagógico. A droga foi administrada em nova forma de apresentação: solução, para uso oral, a 6%.Twenty children, with the diagnosis of cerebral palsy (CP and under classical, physiotherapeutical and pedagogical, treatment, received piracetam (pyrrolidine acetamide as an auxiliary drug. The goal was to better spasticity, learning and nervous instability problems aiming at better results of over-all treatment of CP. The group that received the drug has been compared to a control group of 20 children treated by the customary treatment only. The comparison showed favourable results for the medicated group. The drug was administered in the dose of 80 mg/kg/day during 10 weeks. The criteria for evaluation have been psychological, clinical, physiotherapeutical and pedagogical. The drug has been given in a new form of presentation: 6% solution for oral use.

  18. Authentication of Polygonati Odorati Rhizoma and other two Chinese Materia Medica of the Liliaceae family by pharmacognosy technique with GC-MS analysis.

    Science.gov (United States)

    Liu, Yingjiao; Liu, Canhuang; Yu, Yafei; Xu, Bei; Gong, Limin; Zeng, Xiaoyan; Xiao, Lan; Cheng, Qilai; Liu, Tasi

    2015-02-01

    Yuzhu (Polygonati Odorati Rhizoma), Kangdingyuzhu (Polygonati Prattii Rhizoma), and zhugenqiyuzhu (Disporopsis Fuscopictae Rhizoma) are of the same family, but of different genera. They have all often used in Chinese Materia Medica (CMM) as Polygonati Odorati Rhizoma in China market. Three species of CMM are confused. For better application, we need to identify these plants accurately. This study use pharmacognosy technique and GC-MS analysis, three species of CMM were authenticated. In macroscopic characteristics, the fruit of Polygonati Odorati Rhizoma is blue-black, while the other two are maroon and dark purple orderly. Nodes of Polygonati Odorati Rhizoma are upward and light uplift, about 1 cm spacing, while the other are not. As for microscopic characteristics, the cortex of Polygonati Odorati Rhizoma only occupies about 1/5 of the radius of the transverse section with inconspicuous endodermis, which is much smaller than others. The type of vascular bundles of Polygonati Odorati Rhizoma is closed collateral, but the other is amphivasal. Raphides of calcium oxalate are scattered, but Raphides of the other two are like brooms and neat rows. GC-MS analysis of essential oil could provide different characteristics to distinguish three species. Twenty-three compounds were identified from essential oil of Polygonati Odorati Rhizoma and the main components were n-hexadecanoic acid (49.45%), while n-hexadecanoic acid of the other two are 23.92% and 9.45%. The content of n-hexadecanoic is strongly different. This research was aimed to establish a method by pharmacognosy and GC-MS analysis to identify three CMM and for providing scientifical data to ensure accuracy of origin of three species. © 2014 Wiley Periodicals, Inc.

  19. UNE INTERPRETATION DU TAUX DE CHANGE

    Directory of Open Access Journals (Sweden)

    Galina ULIAN

    2015-03-01

    Full Text Available Dans l’étude ci-dessous on a été réalisé une interprétation de l'impact des fluctuations des taux de change du leu moldave (MDL sur certaines variables économiques. La période considérée est Novembre-Décembre 2014 et le début de l'année 2015. Notamment au cours de cette période, le taux de la monnaie nationale par rapport aux principales devises de référence de change a commencé la voie de fortes dévaluations. Cette tendance, cependant, s’est placée dans le contexte des situations similaires dans la région, qui a ainsi permis sa dépréciation graduelle. Compte tenu que la dépréciation de la monnaie est un phénomène aux effets complexes et multilatérales, une fois arrivé dans un pays "X", celui-ci devrait, afin d'améliorer la situation, en premier lieu, augmenter leur présence sur d'autres marchés de ventes, plus stable et avec de plus grandes possibilités.

  20. Contes et histoires du Yémen

    Directory of Open Access Journals (Sweden)

    Muhammad 'Alî Abduh

    2001-09-01

    Full Text Available Deux contes de la région de Taez, traduits en français, illustrent plusieurs aspects de la vie sociale traditionnelle des villages yéménites. " La brebis devenue hyène " conte les mésaventures d'un groupe d'hommes partis pour une lointaine visite, chargés de qat et accompagnés d'une brebis. " La divination par les os " met en scène le face-à-face entre l'honneur perdu d'un cheikh et celui du hérault de sa tribu.Traditional Tales of YemenThe two tales from the Taez area, translated into French, express different aspects of the traditional social life in Yemeni villages. "The sheep that became a hyena" is about the misfortunes of a group of men that left for a journey transporting qat and a sheep. The other, "Divination by bones", consists in a direct exchange between the lost  honour of a sheikh and the one of the tribe’s herald.

  1. Les premiers tours du monde à forfait. L’exemple de la Société des Voyages d’Etudes Autour du Monde (1878)

    OpenAIRE

    Gauthier, Lionel

    2012-01-01

    Dans la seconde moitié du XIXe siècle, avec le développement du bateau à vapeur et du chemin de fer, et l’ouverture de nouveaux axes de transport comme le Canal de Suez, le voyage autour du monde devient envisageable pour les touristes. Ainsi, dès 1872 des tours du monde à forfait sont organisés, ce qui témoigne de l’entrée du voyage autour du monde dans l’industrie touristique naissante. Cet article étudie ces premiers voyages d’un nouveau genre à travers l’exemple de la Société des Voyages ...

  2. Mise à jour sur le nouveau vaccin 9-valent pour la prévention du virus du papillome humain

    Science.gov (United States)

    Yang, David Yi; Bracken, Keyna

    2016-01-01

    Résumé Objectif Informer les médecins de famille quant à l’efficacité, à l’innocuité, aux effets sur la santé publique et à la rentabilité du vaccin 9-valent contre le virus du papillome humain (VPH). Qualité des données Des articles pertinents publiés dans PubMed jusqu’en mai 2015 ont été examinés et analysés. La plupart des données citées sont de niveau I (essais randomisés et contrôlés et méta-analyses) ou de niveau II (études transversales, cas-témoins et épidémiologiques). Des rapports et recommandations du gouvernement sont aussi cités en référence. Message principal Le vaccin 9-valent contre le VPH, qui offre une protection contre les types 6, 11, 16, 18, 31, 33, 45, 52 et 58 du VPH, est sûr et efficace et réduira encore plus l’incidence des infections à VPH, de même que les cas de cancer lié au VPH. Il peut également protéger indirectement les personnes non immunisées par l’entremise du phénomène d’immunité collective. Un programme d’immunisation efficace peut prévenir la plupart des cancers du col de l’utérus. Les analyses montrent que la rentabilité du vaccin 9-valent chez les femmes est comparable à celle du vaccin quadrivalent original contre le VPH (qui protège contre les types 6, 11, 16 et 18 du VPH) en usage à l’heure actuelle. Toutefois, il faut investiguer plus en profondeur l’utilité d’immuniser les garçons avec le vaccin 9-valent contre le VPH. Conclusion en plus d’être sûr, le vaccin 9-valent protège mieux contre le VPH que le vaccin quadrivalent. Une analyse coûtefficacité en favorise l’emploi, du moins chez les adolescentes. Ainsi, les médecins devraient recommander le vaccin 9-valent à leurs patients plutôt que le vaccin quadrivalent contre le VPH.

  3. Élévation du niveau de la mer dans la zone côtière du delta du Nil

    International Development Research Centre (IDRC) Digital Library (Canada)

    l'eau, l'Institut d'études supérieures de l'Université d'Alexandrie et le Center for Development Services, une équipe de ... Selon un indice élaboré par l'équipe, les villes de Gamasa, ... La qualité du logement, des infrastructures et des services.

  4. Identification des matériaux et étude du bâti : l’exemple du Clos du Cotentin

    Directory of Open Access Journals (Sweden)

    Julien Deshayes

    2012-04-01

    Full Text Available Partant de l’architecture vernaculaire de la Presqu’île du Cotentin, cette étude s’attache à montrer comment l'identification des matériaux de construction, replacée dans une problématique historique, peut fournir un outil d'analyse privilégié du bâti, notamment en matière de chronologie. L'identification des principaux centres carriers et de leur aire d'exportation permet de mieux appréhender l'évolution des modénatures et de raisonner sur des typologies cohérentes. L'acquisition de tels critères d'analyse, peu généralisables hors de régions très délimitées, est nécessairement liée à une expérience prolongée du terrain. L’exemple du Clos du Cotentin offre, en matière d'identification des matériaux et d'étude du bâti, un manifeste en faveur d'une approche topographique approfondie, susceptible de replacer l'architecture rurale dans le cadre d'une évolution historique.Based on the vernacular architecture of the Cotentin peninsula, this article sets out to show how the identification of construction materials, placed in a historical context, can offer a particularly useful tool for analysing buildings, notably for their chronology. The identification of the principle stone quarries and their zones of commercial influence gives information on the evolution of architectural proportions and permits the development of coherent typologies. The acquisition of such analytical criteria is difficult to generalise beyond strictly limited regions and are necessarily linked with in-depth familiarity with the territory concerned. The example that the Clos du Cotentin offers for the identification of building materials and the study of buildings may be seen as a manifesto in favour of a detailed topographical approach, capable of placing rural architecture in the framework of its historical evolution.

  5. Le kyste hydatique du cordon spermatique: une localisation exceptionnelle

    Science.gov (United States)

    Hamdane, Mohamed Moncef; Bougrine, Fethi; Msakni, Issam; Dhaoui-Ghozzi, Amen; Bouziani, Ammar

    2011-01-01

    L’ hydatidose est une anthropo-zoonose due au développement chez l'homme de la forme larvaire du taenia Echinococcus granulosis. La plupart des kystes hydatiques se localisent dans le foie et les poumons. Le kyste hydatique du cordon spermatique est extrêmement rare avec seulement 4 cas rapportés dans la littérature. Les auteurs rapportent dans cet article un nouveau cas d'hydatidose du cordon spermatique. Il s'agissait d'un homme de 40 ans qui consultait pour des douleurs scrotales évoluant depuis huit mois. L'examen clinique a mis en évidence une tuméfaction mobile, inguino-scrotale, droite. L’échographie testiculaire a objectivé une hernie inguinale droite associée à deux kystes épididymaires bilatéraux. Le patient a été opéré pour cure de son hernie avec découverte en per-opératoire d'un kyste du cordon spermatique qui a été réséqué. L'examen anatomopathologique a conclu à une hydatidose du cordon spermatique. PMID:22384304

  6. Violence et dire, pour une rhétorique du soin

    Directory of Open Access Journals (Sweden)

    André Quaderi

    Full Text Available Par une approche plurielle (psychopathologie du travail, sciences du langage et psychanalyse et au travers d’une clinique de type groupe de parole en institution gériatrique, il est abordé les phénomènes de violences. Les effets du dire, au niveau du clinicien, induisent des changements de comportements des soignants dont les causes sont abordées. Ainsi, la taylorisation de l’organisation inhibe la relation du soignant à l’autre et fige le travail dans une exécution de tâche. Ces effets délétères sont à rapporter au Thanatos tout comme les effets du dire (interprété comme une rhétorique du soin sont à comprendre du côté de l’Eros.

  7. Diffusion libre du droit est-elle acquise... pour de bon? | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Depuis, un mouvement de la diffusion libre du droit, soutenu par les instituts ... des documents juridiques des documents du domaine public, consultables en ligne ... International Water Resources Association, in close collaboration with IDRC, ...

  8. Les écueils du double jeu

    Directory of Open Access Journals (Sweden)

    Séverin Muller

    2007-06-01

    Full Text Available À partir d’une expérience d’observation participante qui a consisté à travailler comme ouvrier puis à intégrer les bureaux de la direction dans un abattoir industriel, l’auteur étudie les effets cognitifs de la transgression d’un ordre établi dans l’entreprise : les ouvriers avec les ouvriers et les cadres avec les cadres. Les situations décrites de rupture avec les usages du milieu permettent de réfléchir aux façons d’être identifié selon les circonstances, aux formes d’instrumentalisation du chercheur sur son terrain, aux manières dont la confiance s’acquiert se maintient ou se perd dans un environnement conflictuel (selon quels critères propres à chaque groupe sommes nous acceptés, cooptés ou exclus ?. Finalement, la démarche transversale et le jeu transgressif qu’elle suggère participent à l’apprentissage des systèmes de référence non partagés au sein d’une même organisation.Starting from an experiment of participating observation which consisted in working as worker then to integrate the offices of the direction in an industrial slaughterhouse, the author studies the cognitive effects of the transgression of an order established in the company: workers with the workers and managers with the managers. The described situations of rupture with the uses of the social sphere make it possible to think of the ways of being identified according to circumstances, the shapes of « instrumentalisation » of the researcher on his field, with the ways in which confidence is acquired, is maintained or lost in a conflict environment (according to which specific criteria to each group are us accepted, co-opted or excluded?. Finally, the transverse way and the transgressive play that it suggests take part in the training of the systems of reference not shared in the same organization.A partir de un experimento de observación participante que consistió en trabajar como obrero antes de integrar las

  9. Sainte-Bernardette du Banlay, Nevers

    Directory of Open Access Journals (Sweden)

    Christophe Joly

    2009-11-01

    Full Text Available Construite par Claude Parent et Paul Virilio en 1964-1965, l’église Sainte-Bernadette du Banlay témoigne de leurs travaux sur la fonction oblique. L’édifice fut édifié à l’issue d’un concours d’architecture lancé en 1963 par Mgr Vial et l’Abbé Bourgoin, curé de la paroisse. L’église est inspirée de l’architecture des bunkers. Deux coques de béton s’imbriquent l’une dans l’autre en se décalant par rapport à l’axe longitudinal. L’apparence générale est un édifice monolithique, qui évoque un rocher. Á l’intérieur, deux grands plans obliques paraissent exhumés pour constituer la nef et le chœur. En relation étroite avec la grotte des apparitions de Lourdes, l’église est construite comme une crypte suspendue dont la coupe adopte la forme d’un cœur. Par le choix de matériaux bruts et d’un éclairage zénithal, les architectes confèrent à l’ensemble une étonnante intimité. C’est par l’opposition entre le volume extérieur austère et fermé et l’espace intérieur accueillant et protecteur que les concepteurs expriment la nouvelle fonction d’une église conçue dans une période d’incertitude et de tensions.The Sainte-Bernadette du Banlay church at Nevers was built from 1964 to 1965 to the designs of the architects Claude Parent and Paul Virilio, working on their theme of the oblique function. It was the fruit of an architectural competition organised in 1963 by Monseigneur Vial and the Abbé Bourgoin, the parish priest. The church’s architecture is inspired by that of defensive bunkers. Two reinforced concrete shells are joined the one into the other but out of true on a longitudinal axis. The overall appearance of the church is that of a monolithic block, something like a rock. Inside, two large oblique planes seem to emerge to create the nave and the chancel. Closely related to the Lourdes grotto of the Virgin’s appearances, the church is designed as a suspended crypt

  10. Étude comparée du Liber Judiciorum et du Fuero Juzgo

    Directory of Open Access Journals (Sweden)

    Estelle MAINTIER-VERMOREL

    2009-04-01

    Full Text Available Étant donné sa situation géographique, entre l’Europe et le monde arable, la Castille a joué un rôle particulièrement important, au Moyen Âge, dans le cadre des activités de traduction - notamment avec la célèbre École de Tolède ou les ateliers d’Alphonse X. Cette étude est centrée sur l’une de ces traductions, réalisée sous le règne de Ferdinand III, qui a représenté un point de départ dans le passage des textes officiels du latin au romance. Il s’agit du Fuero Juzgo, un ensemble de lois octroyé, pour la première fois, par Ferdinand III en 1241 à la ville de Cordoue et présenté comme la simple traduction du Liber Judiciorum, élaboré cinq siècles plus tôt dans les Conciles wisigothiques. Nous n’aborderons pas ici cette traduction d’un point de vue linguistique, mais historique et politique. Par le biais d’une comparaison détaillée des prologues des deux textes - qui constituent de véritables traités politiques portant sur le rôle du roi et ses relations avec l’Eglise - nous tenterons de démontrer comment le texte a pu être adapté, au travers de changements minimes mais nombreux et systématiques. Nous essaierons également de montrer pourquoi, dans un contexte de réunion entre Castille et León et également de grande extension du territoire, due à la Reconquête, cette réélaboration subtile du contenu peut être imputée à une manipulation à des fins politiques. Une manipulation, qui plus est, dotée d’une orientation très claire, c’est-à-dire en faveur du roi et au détriment de l’Église - un phénomène qui pourrait constituer les prémices de ce que l’on a coutume d’appeler la genèse de l’État moderne.Dada su situación geográfica, entre Europa y el mundo árabe, Castilla tuvo un papel particularmente importante en el marco de las actividades de traducción durante la Edad Media - especialmente con la famosa Escuela de Toledo o los talleres de Alfonso

  11. Teknologi Pembuatan Cermet Du0¬2 - Steel Untuk Wadah Limbah Bahan Bakar Bekas Pwr

    OpenAIRE

    Alimah, Siti; Budiarto, Budiarto

    2005-01-01

    DUO­2-STEEL CERMET MANUFACTURING TECHNOLOGY FOR PWR Spent Nuclear Fuel (SNF) CASKS. Assessment of DU02 - Steel cermet manufacturing technology for PWR SNF casks has been done. DU02 - Steel cermet consisting of DU02 particulates and other particulates, embedded in a steel matrix. Cermet SNF casks have the potential for superior performance compared with casks constructed of other materials. The addition of DU02 ceramic particulates can increase SNF cask capacity, improve of repository performa...

  12. Promotion des droits de la personne et de la justice du point de vue ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Promotion des droits de la personne et de la justice du point de vue des pays du Sud. À l'heure où des pouvoirs émergents comme la Chine, l'Inde et le Brésil prennent du gallon sur les plans économique et politique, dans les pays du Sud, les organismes de la base s'unissent pour veiller au respect des droits de la ...

  13. Analyse du bruit dans un préamplificateur de harge en technologie ...

    African Journals Online (AJOL)

    Aussi la valeur de l'ENC total est essentiellement dominée par l'expression du bruit thermique du transistor d'entrée et cette derniere peut etre optimisée au détriment de la consommation en jouant sur ID. La valeur du courant de drain et le dimensionnement du transistor d'entrée sont décisifs pour le bruit. Mots-clés : bruit ...

  14. Sud du Sahara | Page 9 | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Un nouveau projet de recherche sur la prévention du VIH a conduit à la réalisation d'un essai national novateur de prévention du VIH au Botswana. Read more about Des résultats de recherche mènent à la réalisation d'essais de prévention du VIH dans l'ensemble du Botswana. Langue French. New research into HIV ...

  15. Spectrographic determination of chlorine and fluorine; Dosage du chlore et du fluor par spectrographie d'emission en atmosphere inerte

    Energy Technology Data Exchange (ETDEWEB)

    Contamin, G [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1965-04-01

    Experimental conditions have been investigated in order to obtain the highest sensitivity in spectrographic determination of chlorine and fluorine using the Fassel method of excitation in an inert atmosphere. The influence of the nature of the atmosphere, of the discharge conditions and of the matrix material has been investigated. The following results have been established: 1. chlorine determination is definitely possible: a working curve has been drawn between 10 {mu}g and 100 {mu}g, the detection limit being around 5 {mu}g; 2. fluorine determination is not satisfactory: the detection limit is still of the order of 80 {mu}g. The best operating conditions have been defined for both elements. (author) [French] Nous avons recherche quelles etaient les conditions permettant d'obtenir la meilleure sensibilite dans le dosage spectrographique du chlore et du fluor par la methode d'excitation en atmosphere inerte (methode de Fassel). Nous avons etudie l'influence de l'atmosphere gazeuse, des conditions de la decharge et du materiau de pastillage. Les points suivants ont ete etablis: 1. le dosage du chlore est possible: une courbe de dosage a ete tracee entre 10 {mu}g et 100 {mu}g et la limite de detection est de l'ordre de 5 {mu}g; 2. le dosage du fluor n'est pas satisfaisant: la limite de detection obtenue etant encore de l'ordre de 80 {mu}g. Les conditions operatoires ont ete precisees pour ces deux elements. (auteur)

  16. Figures du sage et du savoir païens dans le Libro de buen amor

    Directory of Open Access Journals (Sweden)

    Olivier Biaggini

    2013-06-01

    Full Text Available Au-delà de la simple relation de dépendance à ses sources, le Libro de buen amor élabore diverses figures du sage antique, tantôt comme producteur et garant d’une parole d’autorité (Aristote, tantôt, au contraire, comme pur personnage au seuil de la fiction (Virgile. Dans les deux cas, le traitement est largement parodique et remet en question une révérence trop stricte face au système des autorités. Le cas d’Ovide, qui relève conjointement des deux catégories précédentes, est particulièrement intéressant car il montre comment les noms liés à la tradition ovidienne (Ovidio, Nasón, mais aussi Pánfilo, don Amor, doña Venus… sont autant de masques que l’archiprêtre peut successivement adopter et rejeter. Enfin, l’exemplum introductif des Grecs et des Romains est centré sur la transmission du savoir antique pour le placer au fondement du savoir de l’archiprêtre lui-même tout en offrant une représentation de sa part d’incertitude.Más allá de la simple relación de dependencia respecto a sus fuentes, el Libro de buen amor elabora diversas figuras del sabio antiguo, sea como productor y garante de una palabra de autoridad (Aristóteles, sea, al contrario, como mero personaje al borde de la ficción (Virgilio. En ambos casos, el tratamiento aplicado se revela sumamente paródico y pone en tela de juicio una reverencia demasiado estricta para con el sistema de las autoridades. El caso de Ovidio, que corresponde simultáneamente a las dos categorías precedentes, resulta de especial interés al enseñar cómo los nombres ligados a la tradición ovidiana (Ovidio, Nasón, pero también Pánfilo, don Amor, doña Venus… llegan a ser máscaras que el arcipreste puede sucesivamente adoptar y rechazar. Por fin, el exemplum introductorio de los griegos y los romanos se centra en la transmisión del saber antiguo presentándolo como uno de los fundamentos del saber del propio arcipreste al mismo tiempo que ofrece una

  17. Françoise Battagliola, Histoire du travail des femmes

    Directory of Open Access Journals (Sweden)

    Barbara Rist

    2009-06-01

    Full Text Available Initialement paru en 2000, l’ouvrage de Françoise Battagliola vient de bénéficier d’une nouvelle édition : en une centaine de pages denses et bien documentées, l’auteure y brosse un parcours passionnant de l’histoire du travail des femmes en France depuis les débuts de l’industrialisation jus-qu’à la fin du XXe siècle.Le propos s’organise, en gros, selon un axe chronologique, lequel sert de fil conducteur à une problématique voulant éclairer l’histoire, non « des femmes ou du féminin mais des...

  18. Le budget du CNRS de 1969 à 2000.

    OpenAIRE

    Marnot, Bruno

    2011-01-01

    Après avoir abordé l’évolution du budget du CNRS au cours « des années fastes » allant de la Libération à 1968 dans le précédent numéro de cette revue, Bruno Marnot poursuit ici son étude des budgets du Centre sur les trois décennies suivantes. Au cours de cette période, marquée par une conjoncture économique beaucoup moins brillante, les insuffisances budgétaires entraînent une importante diminution des moyens mis à la disposition des laboratoires et mènent à la crise de trésorerie qui sévit...

  19. Commentaires sur la valeur piscicole du Canal de Roubaix (Nord

    Directory of Open Access Journals (Sweden)

    ARRIGNON J.

    1970-10-01

    Full Text Available La population piscicole du Canal de ROUBAIX a été inventoriée par pêche électrique. Trois passages, suivis chacun de l'enlèvement des poissons capturés, ont été opérés dans chacun des trois Secteurs d'inventaire. Le peuplement le plus probable ainsi estimé (par la méthode De Lury,est en rapport avec le degré de pollution du canal. On constate aussi queles poissons se cantonnent le long des berges, sur une largeur de 2 à 3mètres.L'estimation à l'hectare représente donc en réalité le stock d'une zone n'ayant que 25 % de la surface totale du Canal. Les poissons contrôlés sont pour la plupart des poissons de repeuplement.

  20. LA MEDITERRANEE DANS LES RELATIONS INTERNATIONALES DU XXE SIECLE

    OpenAIRE

    Lejeune , Dominique

    2010-01-01

    DEUG; Le monde est jugé dangereux et on voit resurgir les " ennemis héréditaires " ou des adversaires potentiels qui s'y substituent. De plus, l'expansion économique européenne provoque l'impatience d'ascension sociale, et la guerre va pouvoir libérer des énergies en 1914. Les ouvrages de guerre-fiction sont beaucoup plus nombreux après 1905 qu'auparavant ; la guerre est toujours présentée comme devant être courte, à cause de l'importance du nombre des mobilisés et du modernisme du matériel. ...

  1. The electroreduction of pentavalent protactinium; Reduction electrolytique du protactinium pentavalent

    Energy Technology Data Exchange (ETDEWEB)

    Musikas, C [Commissariat a l' Energie Atomique, Centre d' Etudes Nucleaires de Fontenay-aux-Roses, 92 (France)

    1966-05-01

    The reduction of pentavalent protactinium to tetravalent protactinium, in sulfuric and hydrochloric media, on a milligram scale was demonstrated by electrolysis in a separate-compartment cell. There was no indication that protactinium may exist at the trivalent state in these solutions. Polarograms in fluoride solutions showed only one reduction wave. The principle of a volumetric method for the titration of protactinium is given. (author) [French] La reduction du protactinium pentavalent en protactinium tetravalent, dans des solutions sulfuriques et chlorhydriques a ete realisee a l'echelle du milligramme, par electrolyse, dans une cellule a compartiments separes. Aucun indice ne permet de penser que le protactinium puisse exister dans ces solutions a l'etat trivalent. De plus les polarogrammes traces en milieu fluorhydrique ne font apparaitre qu'une seule vague de reduction. Le principe d'une methode volumetrique de dosage du protactinium est donne. (auteur)

  2. Tour du canton de Genève 2017

    CERN Multimedia

    CERN Running club

    2017-01-01

    Pour rappel, le tour du canton est un évènement incontournable pour les coureurs de la région genevoise. Une épreuve qui a lieu le mercredi soir et qui se déroule sur 4 étapes.  Le Running Club du CERN a encore brillé cette année en obtenant de très bons résultats en individuel et surtout par équipe. L’équipe femme monte sur la première marche du podium (voir photo jointe) Les deux premières équipes hommes se classent 2e et 4e sur 51 équipes classées. Voir classement complet ici : http://www.sport-info.com/i_resultats.php?id=113

  3. DU Processing Efficiency and Reclamation: Plasma Arc Melting

    Energy Technology Data Exchange (ETDEWEB)

    Imhoff, Seth D. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Aikin, Jr., Robert M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Swenson, Hunter [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Solis, Eunice Martinez [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-09-26

    The work described here corresponds to one piece of a larger effort to increase material usage efficiency during DU processing operations. In order to achieve this goal, multiple technologies and approaches are being tested. These technologies occupy a spectrum of technology readiness levels (TRLs). Plasma arc melting (PAM) is one of the technologies being investigated. PAM utilizes a high temperature plasma to melt materials. Depending on process conditions, there are potential opportunities for recycling and material reclamation. When last routinely operational, the LANL research PAM showed extremely promising results for recycling and reclamation of DU and DU alloys. The current TRL is lower due to machine idleness for nearly two decades, which has proved difficult to restart. This report describes the existing results, promising techniques, and the process of bringing this technology back to readiness at LANL.

  4. The rise of traditional Chinese medicine and its materia medica: a comparison of the frequency and safety of materials and species used in Europe and China.

    Science.gov (United States)

    Williamson, Elizabeth M; Lorenc, Ava; Booker, Anthony; Robinson, Nicola

    2013-09-16

    Due to the global rise in the use of traditional Chinese medicine (TCM), Chinese materia medica (medicinal materials, or CMM) are giving cause for concern over their evidence base, safety/possible toxicity, questionable quality and use of endangered species of both animals and plants. However, little if anything is actually known about the range of species used to produce CMM used in Europe and even in China. This study represents the first attempt to identify and compare the most important CMM used in both regions, to begin the process of assessing the risks to public health and possible future benefits. Data were collected from a convenience sample of TCM practitioners in the EU and mainland China, using a paper/online survey. Among other questions, respondents were asked (1) which conditions they most commonly treated using CMM and the likelihood of them using herbal manufactured products and decoctions in addition to raw herbs; (2) the perceived frequency with which they observed adverse events to CMM; (3) the frequency and reasons for use of 1 herbal formula and 6 specific individual herbs; (4) an open question about other CMM they used, including materials of non-plant origin. Data were entered into PASW statistics package and analysed using frequency tables, cross-tabulations and chi-squared tests to compare EU and Chinese results. From a total of 747 useable questionnaires (420 from China, 327 from the EU) of those responding from the EU, TCM was generally more commonly used for obstetric/gynaecological and dermatological conditions, compared to neurological and gastrointestinal diseases in China. Disorders treated by Chinese practitioners were more varied, and often more serious, than those treated by their European counterparts, and the range of materials used in China was wider. The potential for toxicity was not high in either region, but although greater in China due to the use of more potent CMM, the incidence of side effects was perceived to be

  5. Comparison of Lamiaceae medicinal uses in eastern Morocco and eastern Andalusia and in Ibn al-Baytar's Compendium of Simple Medicaments (13th century CE).

    Science.gov (United States)

    El-Gharbaoui, Asmae; Benítez, Guillermo; González-Tejero, M Reyes; Molero-Mesa, Joaquín; Merzouki, Abderrahmane

    2017-04-18

    Transmission of traditional knowledge over time and across culturally and historically related territories is an important topic in ethnopharmacology. Here, we contribute to this knowledge by analysing data on medicinal uses in two neighbouring areas of the Western Mediterranean in relation to a historical text that has been scarcely mentioned in historical studies despite its interest. This paper discusses the sharing of popular knowledge on the medicinal uses of plants between eastern Morocco and eastern Andalusia (Spain), focusing on one of the most useful plant families in the Mediterranean area: Lamiaceae. Moreover, we used the classical work of Ibn al-Baytar (13th century CE) The Compendium of Simple Medicaments and Foods as a basis to contrast the possible link of this information, analysing the influence of this historical text on current popular tradition of medicinal plant use in both territories. For data collection, we performed ethnobotanical field research in the eastern part of Morocco, recording current medicinal uses for the Lamiaceae. In addition, we systematically reviewed the ethnobotanical literature from eastern Andalusia, developing a database. We investigated the possible historical link of the shared uses and included in this database the information from Ibn al-Baytar's Compendium. To compare the similarity and diversity of the data, we used Jaccard's similarity index. Our field work provided ethnobotanical information for 14 Lamiaceae species with 95 medicinal uses, serving to treat 13 different pathological groups. Of the total uses recorded in Morocco, 30.5% were shared by eastern Andalusia and found in Ibn al-Baytar's work. There was a higher similarity when comparing current uses of the geographically close territories of eastern Morocco and eastern Andalucía (64%) than for eastern Morocco and this historical text (43%). On the other hand, coincidences between current uses in eastern Andalusia and the ones related in the Compendium

  6. La L.O.L.F. et les projets annuels de performance (P.A.P.) : Elaboration des figures du citoyen, de l'usager, du contribuable et du service public

    OpenAIRE

    Eyraud, Corine

    2006-01-01

    Nous nous intéresserons ici à la fois aux questions de la mesure des effets de l'action publique - ici l'action publique éducative universitaire -, aux dispositifs qui « construisent » les figures de l'usager (en tant que client ?), du citoyen, du contribuable et du service public, et aux nouvelles formes de démocratie que ces dispositifs génèrent (ou pas).

  7. Revelação da ocorrência de erro de medicação em unidade de cuidados intensivos pediátricos Disclosure of medication error in a pediatric intensive care unit

    Directory of Open Access Journals (Sweden)

    Aline Santa Cruz Belela

    2010-09-01

    Full Text Available OBJETIVO: Descrever a ocorrência de comunicação do erro de medicação à equipe e família em uma unidade de cuidados intensivos pediátricos para atendimento de pacientes oncológicos. MÉTODOS: Estudo descritivo e exploratório, realizado no período de 1º de março a 31 de maio de 2008. Foi elaborada e implantada na unidade de cuidados intensivos pediátricos uma ficha de notificação de erros de medicação. A ficha deveria ser preenchida pelos profissionais envolvidos no sistema de medicação da unidade no período definido para coleta de dados. . RESULTADOS: A amostra foi composta por 71 fichas coletadas no período de estudo. Após a detecção do erro de medicação, a ocorrência não foi comunicada à equipe em 34 (47,9% situações. Nos 37 casos nos quais os eventos foram comunicados, o médico (48,7% foi aquele que mais recebeu a informação. Em 95,8% dos relatos a ocorrência não foi informada ao paciente e família. CONCLUSÃO: Embora a literatura atual preconize a revelação do erro, tal prática não constitui atividade freqüente na unidade de cuidados intensivos pediátricos estudada.OBJECTIVE: To describe the frequency medication error disclosure to the team and to the family in an oncology pediatric patients' intensive care unit. METHODS: This was a descriptive and exploratory study performed between March 1 and May 31, 2008. A medication error report form was developed and implemented, to be completed by the professionals involved in the unit's medication process. RESULTS: The sample consisted of 71 forms collected over the 92 collection days. After medication error detection, the event was not reported to the pediatric intensive care unit's team in 34 (47.9% cases. In the 37 reported to the team cases, for most of them (48.7% the physician was the professional communicated. The event was not disclosed to the patient/family in 95.8% of medication error reports. CONCLUSIONS: Although the literature recommends

  8. Nouvelle initiative des chaires de recherche Canada-Afrique du Sud ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    8 déc. 2016 ... Elles s'appuient sur le South African Research Chairs Initiative (SARChl), ainsi que sur le programme de chaires de recherche industrielle, dont le financement provient en partie du Conseil de recherches en sciences naturelles et en génie du Canada (CRSNG) et du Programme des chaires de recherche ...

  9. Histoire et sociétés du Vietnam classique

    OpenAIRE

    Papin, Philippe

    2012-01-01

    Programme de l’année 2008-2009 : I. Histoire rurale de la propriété foncière au Vietnam du XVIe au XVIIIe siècle. — II. Étude des sources de l’histoire villageoise du bassin du fleuve Rouge à l’époque moderne.

  10. Changements à la tête du CERN - Robert Aymar aux commandes pour 5 ans.

    CERN Multimedia

    2003-01-01

    "Une nouvelle équipe prendra les rênes du CERN à partir du 1er janvier. Le Francais Robert Aymar, anciennement directeur du Projet de reacteur thermonucleaire experimental international (ITER), dirigera le centre de recherche pour la periode 2004-2008" (1 page).

  11. Etablissement du pollutogramme et de l'hydrogramme de la rivière ...

    African Journals Online (AJOL)

    Ecole d'Aquaculture de la Vallée, Université Nationale d'Agriculture, République du Bénin. ... obtenus ont montré qu'à partir du point de déversement des eaux provenant de la station d'épuration, .... qualité physico-chimique et biologique du.

  12. 1 Commande multivariable du moteur asynchrone triphasé à cage ...

    African Journals Online (AJOL)

    AKA BOKO

    Correspondance, courriel : rabenarivo.michel@yahoo.fr. Résumé. La commande du moteur asynchrone triphasé à ... synthèse du système à l'aide du logiciel MATLAB. Mots-clés : commande, système multivariable, variation de ... of the system by MATLAB software. Keywords : control, MIMO system, frequency variation, ...

  13. 23 Contribution à l'étude de la radioactivité gamma du sable des ...

    African Journals Online (AJOL)

    BRIANT

    Résumé. Les familles de l'Uranium -238, de l'Uranium -235, du Thorium -232 et du .... En rapportant les valeurs du Tableau 1 dans les équations (2) et (3), les ..... “Determination of Natural Radioactivity Levels in the State of Qatar Using High-.

  14. Asie du sud | Page 38 | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Asie du sud. Asie du sud. Read more about Advancing LDCs Interests in the WTO: Strengthening Participation, Securing Priorities (TTI). Langue English. Read more about Resserrement des réseaux pour la lutte contre les maladies infectieuses émergentes en Asie du Sud-Est et en Chine - 2e phase de l'APEIR. Langue ...

  15. Vers l'integration des textes dans le programme du fran9ais langue ...

    African Journals Online (AJOL)

    Au Malawi, on enseigne le fran9ais en tant que langue etrangere depuis une quarantaine d'annees .... !'organisation institutionnelle du systeme educatif du Malawi, le palier secondaire en ... Les objectifs du type : rediger une lettre, decrire une .... nouveau (rheme). Charolles souligne qu'il s'agit d'une performance delicate.

  16. Des solutions fiscales pour une réduction optimale du tabagisme en ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Centre de recherches pour le développement international Gouvernement du Canada ... taxation du tabac, l¿insuffisance de données probantes locales constitue ... de taxes sur les recettes fiscales de leur gouvernement et sur la santé publique, et de ... Dans ce bulletin du BRAS: Faites connaissance avec Kathryn Touré, ...

  17. Promotion de la recherche sur l'entrepreneuriat en Asie du Sud-Est ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    en Malaisie) assurera la coordination du projet, auquel participeront également la Chambre de commerce et de l'industrie du Vietnam, ... En Asie du Sud, la plupart des travailleurs ont un emploi mal rémunéré n'offrant aucune protection sociale.

  18. The Effect of Chlorothiazide on Caesium-137 Excretion in Human Subjects; Effet de la Chiorothiazide sur l'Elimination du Cesium 137 chez l'Homme; 0412 041b 0414 ; Influencia de la Ciorotiazida sobre la Excrecion de Cesio en el Hombre

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, Joan; McNeill, K. G. [Departments of Medicine and Physics, University of Toronto, ON (Canada)

    1964-11-15

    time to determine the effect of basal metabolism on caesium excretion and these results will also be reported. (author) [French] L'etude avait pour objet de determiner les facteurs qui influent sur le metabolisme du cesium chez des sujets normaux, en vue notamment d'etablir une therapie qui permettrait de reduite la charge corporelle de cesium. Etant donne que le cesium et le potassium sont chimiquement semblables et qu'ils sont localises l'un et l'autre dans le compartiment intracellulaire de l'organisme, principalement dans le tissu musculaire, il a semble aux auteurs que la chlorothiazide, qui stimule fortement l'elimination urinaire du potassium, pouvait augmenter aussi la quantite de cesium elimine. Ils ont administre a quatre sujets normaux une dose unique de 0,1 {mu}c. de cesium 137 par voie buccale. Deux des sujets ont alors recu de la chlorothiazide a raison de 2,0 g/j pendant trois jours consecutifs, a compter d'une heure apres l'absorption du cesium. La dose de chlorothiazide a ete administree a nouveau apres deux semaines. Les deux autres sujets ont servi de temoins. La charge corporelle de cesium 137 a ete mesuree a l'aide d'un anthropogammametre, 3 des intervalles de temps allant jusqu'a 320 j. Les auteurs ont recueilli les urines de 24 h, d'abord pendant trois jours a des fins de controle, puis pendant les 20 j qui ont suivi l'absorption de cesium. Ils ont analyse les echantillons afin de determiner les electrolytes et l'activite du cesium. la chlorothiazide a augmente la quantite de potassium eliminee, qui a atteint jusqu'a 1,5 fois les valeurs temoins, mais elle n'a pas eu d'effet significatif sur l'elimination du cesium et n'a pas non plus reduit sensiblement la charge corporelle de cesium. Chez tous les sujets, une faible fraction de Cs (10 a 20%) a ete eliminee rapidement, la periode biologique (T{sub b}) etant inferieure a 1 j. Le reste a ete elimine a un taux constant, Tb etant de 90 a 155 j. Plus de 70 Degree-Sign jo du cesium elimine

  19. Use of Take-set system for radiopharmaceutical labelling: example of indium-111 labeled pentetreotide (Octreoscan) preparation; Utilisation du systeme Take-set pour le radiomarquage des medicaments radiopharmaceutiques: exemple de la preparation du pentetreotide marque a l'indium 111 (Octreoscan)

    Energy Technology Data Exchange (ETDEWEB)

    Ben Reguiga, M.; Sinegre, M. [Hopital Beaujon, Unite de Radiopharmacie, Service de Pharmacie-toxicologie, 92 - Clichy (France); Besse, H.; Stievenart, J.L.; Le Guludec, D. [Hopital Beaujon, Service de Medecine Nucleaire92 - Clichy (France)

    2009-09-15

    The quality of indium 111 radiolabelled pentetreotide preparation (Octreoscan, Covidien) depends on several factors among which the use of a special transfer needle (Sterican) especially conceived to avoid the metal impurities introduction into the reactional medium during labelling. This device, usually provided by the supplier, can exceptionally present defects (twisted needle, folded bevel...) preventing its use for the preparation. In order to manage this risk, we propose in the present technical note an alternative labelling method, based on an adaptation of the original one and using another transfer device, the Take-setSWAN system, which permits to obtain high quality Octreoscan preparations that meet the product approval specifications. (authors)

  20. Surveillant militaire, j’ai vu la fin du bagne

    Directory of Open Access Journals (Sweden)

    Marc Renneville

    2006-01-01

    Full Text Available Surveillant principal (assimilé Lieutenant, Emile Demaret est peut-être le dernier survivant du corps des surveillants militaires des services pénitentiaires coloniaux de la Guyane. Né le 26 juin 1918 à Toulouse, il a été mousse à l’Ecole des Apprentis marins de Brest le 4 avril 1934, engagé dans la Marine nationale pour cinq ans à partir du 17 août 1934, embarqué sur les cuirassés Jean Bart et Paris, matelot timonier le 1er octobre 1935 sur le torpilleur Enseigne Roux à Bizerte (Tunisie, q...