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Sample records for metabolic system machine

  1. Machine Learning Methods for Analysis of Metabolic Data and Metabolic Pathway Modeling.

    Science.gov (United States)

    Cuperlovic-Culf, Miroslava

    2018-01-11

    Machine learning uses experimental data to optimize clustering or classification of samples or features, or to develop, augment or verify models that can be used to predict behavior or properties of systems. It is expected that machine learning will help provide actionable knowledge from a variety of big data including metabolomics data, as well as results of metabolism models. A variety of machine learning methods has been applied in bioinformatics and metabolism analyses including self-organizing maps, support vector machines, the kernel machine, Bayesian networks or fuzzy logic. To a lesser extent, machine learning has also been utilized to take advantage of the increasing availability of genomics and metabolomics data for the optimization of metabolic network models and their analysis. In this context, machine learning has aided the development of metabolic networks, the calculation of parameters for stoichiometric and kinetic models, as well as the analysis of major features in the model for the optimal application of bioreactors. Examples of this very interesting, albeit highly complex, application of machine learning for metabolism modeling will be the primary focus of this review presenting several different types of applications for model optimization, parameter determination or system analysis using models, as well as the utilization of several different types of machine learning technologies.

  2. Machine Learning Methods for Analysis of Metabolic Data and Metabolic Pathway Modeling

    Science.gov (United States)

    Cuperlovic-Culf, Miroslava

    2018-01-01

    Machine learning uses experimental data to optimize clustering or classification of samples or features, or to develop, augment or verify models that can be used to predict behavior or properties of systems. It is expected that machine learning will help provide actionable knowledge from a variety of big data including metabolomics data, as well as results of metabolism models. A variety of machine learning methods has been applied in bioinformatics and metabolism analyses including self-organizing maps, support vector machines, the kernel machine, Bayesian networks or fuzzy logic. To a lesser extent, machine learning has also been utilized to take advantage of the increasing availability of genomics and metabolomics data for the optimization of metabolic network models and their analysis. In this context, machine learning has aided the development of metabolic networks, the calculation of parameters for stoichiometric and kinetic models, as well as the analysis of major features in the model for the optimal application of bioreactors. Examples of this very interesting, albeit highly complex, application of machine learning for metabolism modeling will be the primary focus of this review presenting several different types of applications for model optimization, parameter determination or system analysis using models, as well as the utilization of several different types of machine learning technologies. PMID:29324649

  3. Web-based newborn screening system for metabolic diseases: machine learning versus clinicians.

    Science.gov (United States)

    Chen, Wei-Hsin; Hsieh, Sheau-Ling; Hsu, Kai-Ping; Chen, Han-Ping; Su, Xing-Yu; Tseng, Yi-Ju; Chien, Yin-Hsiu; Hwu, Wuh-Liang; Lai, Feipei

    2013-05-23

    A hospital information system (HIS) that integrates screening data and interpretation of the data is routinely requested by hospitals and parents. However, the accuracy of disease classification may be low because of the disease characteristics and the analytes used for classification. The objective of this study is to describe a system that enhanced the neonatal screening system of the Newborn Screening Center at the National Taiwan University Hospital. The system was designed and deployed according to a service-oriented architecture (SOA) framework under the Web services .NET environment. The system consists of sample collection, testing, diagnosis, evaluation, treatment, and follow-up services among collaborating hospitals. To improve the accuracy of newborn screening, machine learning and optimal feature selection mechanisms were investigated for screening newborns for inborn errors of metabolism. The framework of the Newborn Screening Hospital Information System (NSHIS) used the embedded Health Level Seven (HL7) standards for data exchanges among heterogeneous platforms integrated by Web services in the C# language. In this study, machine learning classification was used to predict phenylketonuria (PKU), hypermethioninemia, and 3-methylcrotonyl-CoA-carboxylase (3-MCC) deficiency. The classification methods used 347,312 newborn dried blood samples collected at the Center between 2006 and 2011. Of these, 220 newborns had values over the diagnostic cutoffs (positive cases) and 1557 had values that were over the screening cutoffs but did not meet the diagnostic cutoffs (suspected cases). The original 35 analytes and the manifested features were ranked based on F score, then combinations of the top 20 ranked features were selected as input features to support vector machine (SVM) classifiers to obtain optimal feature sets. These feature sets were tested using 5-fold cross-validation and optimal models were generated. The datasets collected in year 2011 were used as

  4. Predicting metabolic syndrome using decision tree and support vector machine methods

    Directory of Open Access Journals (Sweden)

    Farzaneh Karimi-Alavijeh

    2016-06-01

    Full Text Available BACKGROUND: Metabolic syndrome which underlies the increased prevalence of cardiovascular disease and Type 2 diabetes is considered as a group of metabolic abnormalities including central obesity, hypertriglyceridemia, glucose intolerance, hypertension, and dyslipidemia. Recently, artificial intelligence based health-care systems are highly regarded because of its success in diagnosis, prediction, and choice of treatment. This study employs machine learning technics for predict the metabolic syndrome. METHODS: This study aims to employ decision tree and support vector machine (SVM to predict the 7-year incidence of metabolic syndrome. This research is a practical one in which data from 2107 participants of Isfahan Cohort Study has been utilized. The subjects without metabolic syndrome according to the ATPIII criteria were selected. The features that have been used in this data set include: gender, age, weight, body mass index, waist circumference, waist-to-hip ratio, hip circumference, physical activity, smoking, hypertension, antihypertensive medication use, systolic blood pressure (BP, diastolic BP, fasting blood sugar, 2-hour blood glucose, triglycerides (TGs, total cholesterol, low-density lipoprotein, high density lipoprotein-cholesterol, mean corpuscular volume, and mean corpuscular hemoglobin. Metabolic syndrome was diagnosed based on ATPIII criteria and two methods of decision tree and SVM were selected to predict the metabolic syndrome. The criteria of sensitivity, specificity and accuracy were used for validation. RESULTS: SVM and decision tree methods were examined according to the criteria of sensitivity, specificity and accuracy. Sensitivity, specificity and accuracy were 0.774 (0.758, 0.74 (0.72 and 0.757 (0.739 in SVM (decision tree method. CONCLUSION: The results show that SVM method sensitivity, specificity and accuracy is more efficient than decision tree. The results of decision tree method show that the TG is the most

  5. Predicting metabolic syndrome using decision tree and support vector machine methods.

    Science.gov (United States)

    Karimi-Alavijeh, Farzaneh; Jalili, Saeed; Sadeghi, Masoumeh

    2016-05-01

    Metabolic syndrome which underlies the increased prevalence of cardiovascular disease and Type 2 diabetes is considered as a group of metabolic abnormalities including central obesity, hypertriglyceridemia, glucose intolerance, hypertension, and dyslipidemia. Recently, artificial intelligence based health-care systems are highly regarded because of its success in diagnosis, prediction, and choice of treatment. This study employs machine learning technics for predict the metabolic syndrome. This study aims to employ decision tree and support vector machine (SVM) to predict the 7-year incidence of metabolic syndrome. This research is a practical one in which data from 2107 participants of Isfahan Cohort Study has been utilized. The subjects without metabolic syndrome according to the ATPIII criteria were selected. The features that have been used in this data set include: gender, age, weight, body mass index, waist circumference, waist-to-hip ratio, hip circumference, physical activity, smoking, hypertension, antihypertensive medication use, systolic blood pressure (BP), diastolic BP, fasting blood sugar, 2-hour blood glucose, triglycerides (TGs), total cholesterol, low-density lipoprotein, high density lipoprotein-cholesterol, mean corpuscular volume, and mean corpuscular hemoglobin. Metabolic syndrome was diagnosed based on ATPIII criteria and two methods of decision tree and SVM were selected to predict the metabolic syndrome. The criteria of sensitivity, specificity and accuracy were used for validation. SVM and decision tree methods were examined according to the criteria of sensitivity, specificity and accuracy. Sensitivity, specificity and accuracy were 0.774 (0.758), 0.74 (0.72) and 0.757 (0.739) in SVM (decision tree) method. The results show that SVM method sensitivity, specificity and accuracy is more efficient than decision tree. The results of decision tree method show that the TG is the most important feature in predicting metabolic syndrome. According

  6. Machine protection systems

    CERN Document Server

    Macpherson, A L

    2010-01-01

    A summary of the Machine Protection System of the LHC is given, with particular attention given to the outstanding issues to be addressed, rather than the successes of the machine protection system from the 2009 run. In particular, the issues of Safe Machine Parameter system, collimation and beam cleaning, the beam dump system and abort gap cleaning, injection and dump protection, and the overall machine protection program for the upcoming run are summarised.

  7. Machine learning methods for metabolic pathway prediction

    Directory of Open Access Journals (Sweden)

    Karp Peter D

    2010-01-01

    Full Text Available Abstract Background A key challenge in systems biology is the reconstruction of an organism's metabolic network from its genome sequence. One strategy for addressing this problem is to predict which metabolic pathways, from a reference database of known pathways, are present in the organism, based on the annotated genome of the organism. Results To quantitatively validate methods for pathway prediction, we developed a large "gold standard" dataset of 5,610 pathway instances known to be present or absent in curated metabolic pathway databases for six organisms. We defined a collection of 123 pathway features, whose information content we evaluated with respect to the gold standard. Feature data were used as input to an extensive collection of machine learning (ML methods, including naïve Bayes, decision trees, and logistic regression, together with feature selection and ensemble methods. We compared the ML methods to the previous PathoLogic algorithm for pathway prediction using the gold standard dataset. We found that ML-based prediction methods can match the performance of the PathoLogic algorithm. PathoLogic achieved an accuracy of 91% and an F-measure of 0.786. The ML-based prediction methods achieved accuracy as high as 91.2% and F-measure as high as 0.787. The ML-based methods output a probability for each predicted pathway, whereas PathoLogic does not, which provides more information to the user and facilitates filtering of predicted pathways. Conclusions ML methods for pathway prediction perform as well as existing methods, and have qualitative advantages in terms of extensibility, tunability, and explainability. More advanced prediction methods and/or more sophisticated input features may improve the performance of ML methods. However, pathway prediction performance appears to be limited largely by the ability to correctly match enzymes to the reactions they catalyze based on genome annotations.

  8. Machine learning methods for metabolic pathway prediction

    Science.gov (United States)

    2010-01-01

    Background A key challenge in systems biology is the reconstruction of an organism's metabolic network from its genome sequence. One strategy for addressing this problem is to predict which metabolic pathways, from a reference database of known pathways, are present in the organism, based on the annotated genome of the organism. Results To quantitatively validate methods for pathway prediction, we developed a large "gold standard" dataset of 5,610 pathway instances known to be present or absent in curated metabolic pathway databases for six organisms. We defined a collection of 123 pathway features, whose information content we evaluated with respect to the gold standard. Feature data were used as input to an extensive collection of machine learning (ML) methods, including naïve Bayes, decision trees, and logistic regression, together with feature selection and ensemble methods. We compared the ML methods to the previous PathoLogic algorithm for pathway prediction using the gold standard dataset. We found that ML-based prediction methods can match the performance of the PathoLogic algorithm. PathoLogic achieved an accuracy of 91% and an F-measure of 0.786. The ML-based prediction methods achieved accuracy as high as 91.2% and F-measure as high as 0.787. The ML-based methods output a probability for each predicted pathway, whereas PathoLogic does not, which provides more information to the user and facilitates filtering of predicted pathways. Conclusions ML methods for pathway prediction perform as well as existing methods, and have qualitative advantages in terms of extensibility, tunability, and explainability. More advanced prediction methods and/or more sophisticated input features may improve the performance of ML methods. However, pathway prediction performance appears to be limited largely by the ability to correctly match enzymes to the reactions they catalyze based on genome annotations. PMID:20064214

  9. Research on the proficient machine system. Theoretical part; Jukutatsu machine system no chosa kenkyu. Rironhen

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    The basic theory of the proficient machine system to be developed was studied. Important proficient techniques in manufacturing industries are becoming extinct because of insufficient succession to next generation. The proficient machine system was proposed to cope with such situation. This machine system includes the mechanism for progress and evolution of techniques and sensibilities to be adaptable to environmental changes by learning and recognizing various motions such as work and process. Consequently, the basic research fields are composed of thought, learning, perception and action. This machine requires not only deigned fixed functions but also introduction of the same proficient concept as human being to be adaptable to changes in situation, purpose, time and machine`s complexity. This report explains in detail the basic concept, system principle, approaching procedure and practical elemental technologies of the proficient machine system, and also describes the future prospect. 133 refs., 110 figs., 7 tabs.

  10. Advanced Electrical Machines and Machine-Based Systems for Electric and Hybrid Vehicles

    Directory of Open Access Journals (Sweden)

    Ming Cheng

    2015-09-01

    Full Text Available The paper presents a number of advanced solutions on electric machines and machine-based systems for the powertrain of electric vehicles (EVs. Two types of systems are considered, namely the drive systems designated to the EV propulsion and the power split devices utilized in the popular series-parallel hybrid electric vehicle architecture. After reviewing the main requirements for the electric drive systems, the paper illustrates advanced electric machine topologies, including a stator permanent magnet (stator-PM motor, a hybrid-excitation motor, a flux memory motor and a redundant motor structure. Then, it illustrates advanced electric drive systems, such as the magnetic-geared in-wheel drive and the integrated starter generator (ISG. Finally, three machine-based implementations of the power split devices are expounded, built up around the dual-rotor PM machine, the dual-stator PM brushless machine and the magnetic-geared dual-rotor machine. As a conclusion, the development trends in the field of electric machines and machine-based systems for EVs are summarized.

  11. Machine vision systems using machine learning for industrial product inspection

    Science.gov (United States)

    Lu, Yi; Chen, Tie Q.; Chen, Jie; Zhang, Jian; Tisler, Anthony

    2002-02-01

    Machine vision inspection requires efficient processing time and accurate results. In this paper, we present a machine vision inspection architecture, SMV (Smart Machine Vision). SMV decomposes a machine vision inspection problem into two stages, Learning Inspection Features (LIF), and On-Line Inspection (OLI). The LIF is designed to learn visual inspection features from design data and/or from inspection products. During the OLI stage, the inspection system uses the knowledge learnt by the LIF component to inspect the visual features of products. In this paper we will present two machine vision inspection systems developed under the SMV architecture for two different types of products, Printed Circuit Board (PCB) and Vacuum Florescent Displaying (VFD) boards. In the VFD board inspection system, the LIF component learns inspection features from a VFD board and its displaying patterns. In the PCB board inspection system, the LIF learns the inspection features from the CAD file of a PCB board. In both systems, the LIF component also incorporates interactive learning to make the inspection system more powerful and efficient. The VFD system has been deployed successfully in three different manufacturing companies and the PCB inspection system is the process of being deployed in a manufacturing plant.

  12. Machine learning systems

    Energy Technology Data Exchange (ETDEWEB)

    Forsyth, R

    1984-05-01

    With the dramatic rise of expert systems has come a renewed interest in the fuel that drives them-knowledge. For it is specialist knowledge which gives expert systems their power. But extracting knowledge from human experts in symbolic form has proved arduous and labour-intensive. So the idea of machine learning is enjoying a renaissance. Machine learning is any automatic improvement in the performance of a computer system over time, as a result of experience. Thus a learning algorithm seeks to do one or more of the following: cover a wider range of problems, deliver more accurate solutions, obtain answers more cheaply, and simplify codified knowledge. 6 references.

  13. Advanced Electrical Machines and Machine-Based Systems for Electric and Hybrid Vehicles

    OpenAIRE

    Ming Cheng; Le Sun; Giuseppe Buja; Lihua Song

    2015-01-01

    The paper presents a number of advanced solutions on electric machines and machine-based systems for the powertrain of electric vehicles (EVs). Two types of systems are considered, namely the drive systems designated to the EV propulsion and the power split devices utilized in the popular series-parallel hybrid electric vehicle architecture. After reviewing the main requirements for the electric drive systems, the paper illustrates advanced electric machine topologies, including a stator perm...

  14. Machine Directional Register System Modeling for Shaft-Less Drive Gravure Printing Machines

    Directory of Open Access Journals (Sweden)

    Shanhui Liu

    2013-01-01

    Full Text Available In the latest type of gravure printing machines referred to as the shaft-less drive system, each gravure printing roller is driven by an individual servo motor, and all motors are electrically synchronized. The register error is regulated by a speed difference between the adjacent printing rollers. In order to improve the control accuracy of register system, an accurate mathematical model of the register system should be investigated for the latest machines. Therefore, the mathematical model of the machine directional register (MDR system is studied for the multicolor gravure printing machines in this paper. According to the definition of the MDR error, the model is derived, and then it is validated by the numerical simulation and experiments carried out in the experimental setup of the four-color gravure printing machines. The results show that the established MDR system model is accurate and reliable.

  15. Smile (System/Machine-Independent Local Environment)

    Energy Technology Data Exchange (ETDEWEB)

    Fletcher, J.G.

    1988-04-01

    This document defines the characteristics of Smile, a System/machine-independent local environment. This environment consists primarily of a number of primitives (types, macros, procedure calls, and variables) that a program may use; these primitives provide facilities, such as memory allocation, timing, tasking and synchronization beyond those typically provided by a programming language. The intent is that a program will be portable from system to system and from machine to machine if it relies only on the portable aspects of its programming language and on the Smile primitives. For this to be so, Smile itself must be implemented on each system and machine, most likely using non-portable constructions; that is, while the environment provided by Smile is intended to be portable, the implementation of Smile is not necessarily so. In order to make the implementation of Smile as easy as possible and thereby expedite the porting of programs to a new system or a new machine, Smile has been defined to provide a minimal portable environment; that is, simple primitives are defined, out of which more complex facilities may be constructed using portable procedures. The implementation of Smile can be as any of the following: the underlying software environment for the operating system of an otherwise {open_quotes}bare{close_quotes} machine, a {open_quotes}guest{close_quotes} system environment built upon a preexisting operating system, an environment within a {open_quotes}user{close_quotes} process run by an operating system, or a single environment for an entire machine, encompassing both system and {open_quotes}user{close_quotes} processes. In the first three of these cases the tasks provided by Smile are {open_quotes}lightweight processes{close_quotes} multiplexed within preexisting processes or the system, while in the last case they also include the system processes themselves.

  16. Man Machine Systems in Education.

    Science.gov (United States)

    Sall, Malkit S.

    This review of the research literature on the interaction between humans and computers discusses how man machine systems can be utilized effectively in the learning-teaching process, especially in secondary education. Beginning with a definition of man machine systems and comments on the poor quality of much of the computer-based learning material…

  17. Fully automatic CNC machining production system

    Directory of Open Access Journals (Sweden)

    Lee Jeng-Dao

    2017-01-01

    Full Text Available Customized manufacturing is increasing years by years. The consumption habits change has been cause the shorter of product life cycle. Therefore, many countries view industry 4.0 as a target to achieve more efficient and more flexible automated production. To develop an automatic loading and unloading CNC machining system via vision inspection is the first step in industrial upgrading. CNC controller is adopted as the main controller to command to the robot, conveyor, and other equipment in this study. Moreover, machine vision systems are used to detect position of material on the conveyor and the edge of the machining material. In addition, Open CNC and SCADA software will be utilized to make real-time monitor, remote system of control, alarm email notification, and parameters collection. Furthermore, RFID has been added to employee classification and management. The machine handshaking has been successfully proposed to achieve automatic vision detect, edge tracing measurement, machining and system parameters collection for data analysis to accomplish industrial automation system integration with real-time monitor.

  18. Collaborative Systems – Finite State Machines

    Directory of Open Access Journals (Sweden)

    Ion IVAN

    2011-01-01

    Full Text Available In this paper the finite state machines are defined and formalized. There are presented the collaborative banking systems and their correspondence is done with finite state machines. It highlights the role of finite state machines in the complexity analysis and performs operations on very large virtual databases as finite state machines. It builds the state diagram and presents the commands and documents transition between the collaborative systems states. The paper analyzes the data sets from Collaborative Multicash Servicedesk application and performs a combined analysis in order to determine certain statistics. Indicators are obtained, such as the number of requests by category and the load degree of an agent in the collaborative system.

  19. Machine Protection System response in 2011

    CERN Document Server

    Zerlauth, M; Wenninger, J

    2012-01-01

    The performance of the machine protection system during the 2011 run is summarized in this paper. Following an analysis of the beam dump causes in comparison to the previous 2010 run, special emphasis will be given to analyse events which risked to exposed parts of the machine to damage. Further improvements and mitigations of potential holes in the protection systems as well as in the change management will be evaluated along with their impact on the 2012 run. The role of the restricted Machine Protection Panel ( rMPP ) during the various operational phases such as commissioning, the intensity ramp up and Machine Developments is being discussed.

  20. Superconducting magnetic systems and electrical machines

    International Nuclear Information System (INIS)

    Glebov, I.A.

    1975-01-01

    The use of superconductors for magnets and electrical machines attracts close attention of designers and scientists. A description is given of an ongoing research program to create superconductive magnetic systems, commutator motors, homopolar machines, topological generators and turbogenerators with superconductive field windings. All the machines are tentative experimental models and serve as a basis for further developments

  1. Smart machine protection system

    International Nuclear Information System (INIS)

    Clark, S.; Nelson, D.; Grillo, A.

    1992-01-01

    A Machine Protection System implemented on the SLC automatically controls the beam repetition rates in the accelerator so that radiation or temperature faults slow the repetition rate to bring the fault within tolerance without shutting down the machine. This process allows the accelerators to aid in the fault diagnostic process, and the protection system automatically restores the beams back to normal rates when the fault is diagnosed and corrected. The user interface includes facilities to monitor the performance of the system, and track rate limits, faults, and recoveries. There is an edit facility to define the devices to be included in the protection system, along with their set points, limits, and trip points. This set point and limit data is downloaded into the CAMAC modules, and the configuration data is complied into a logical decision tree for the 68030 processor. (author)

  2. Smart Machine Protection System

    International Nuclear Information System (INIS)

    Clark, S.; Nelson, D.; Grillo, A.; Spencer, N.; Hutchinson, D.; Olsen, J.; Millsom, D.; White, G.; Gromme, T.; Allison, S.; Underwood, K.; Zelazny, M.; Kang, H.

    1991-11-01

    A Machine Protection System implemented on the SLC automatically controls the beam repetition rates in the accelerator so that radiation or temperature faults slow the repetition rate to bring the fault within tolerance without shutting down the machine. This process allows the accelerator to aid in the fault diagnostic process, and the protection system automatically restores the beams back to normal rates when the fault is diagnosed and corrected. The user interface includes facilities to monitor the performance of the system, and track rate limits, faults, and recoveries. There is an edit facility to define the devices to be included in the protection system, along with their set points, limits, and trip points. This set point and limit data is downloaded into the CAMAC modules, and the configuration data is compiled into a logical decision tree for the 68030 processor. 3 figs

  3. Controls and Machine Protection Systems

    CERN Document Server

    Carrone, E.

    2016-01-01

    Machine protection, as part of accelerator control systems, can be managed with a 'functional safety' approach, which takes into account product life cycle, processes, quality, industrial standards and cybersafety. This paper will discuss strategies to manage such complexity and the related risks, with particular attention to fail-safe design and safety integrity levels, software and hardware standards, testing, and verification philosophy. It will also discuss an implementation of a machine protection system at the SLAC National Accelerator Laboratory's Linac Coherent Light Source (LCLS).

  4. Control System Design for Automatic Cavity Tuning Machines

    Energy Technology Data Exchange (ETDEWEB)

    Carcagno, R.; Khabiboulline, T.; Kotelnikov, S.; Makulski, A.; Nehring, R.; Nogiec, J.; Ross, M.; Schappert, W.; /Fermilab; Goessel, A.; Iversen, J.; Klinke, D.; /DESY

    2009-05-01

    A series of four automatic tuning machines for 9-cell TESLA-type cavities are being developed and fabricated in a collaborative effort among DESY, FNAL, and KEK. These machines are intended to support high-throughput cavity fabrication for construction of large SRF-based accelerator projects. Two of these machines will be delivered to cavity vendors for the tuning of XFEL cavities. The control system for these machines must support a high level of automation adequate for industrial use by non-experts operators. This paper describes the control system hardware and software design for these machines.

  5. Control System Design for Automatic Cavity Tuning Machines

    International Nuclear Information System (INIS)

    Carcagno, R.; Khabiboulline, T.; Kotelnikov, S.; Makulski, A.; Nehring, R.; Nogiec, J.; Ross, M.; Schappert, W.; Goessel, A.; Iversen, J.; Klinke, D.

    2009-01-01

    A series of four automatic tuning machines for 9-cell TESLA-type cavities are being developed and fabricated in a collaborative effort among DESY, FNAL, and KEK. These machines are intended to support high-throughput cavity fabrication for construction of large SRF-based accelerator projects. Two of these machines will be delivered to cavity vendors for the tuning of XFEL cavities. The control system for these machines must support a high level of automation adequate for industrial use by non-experts operators. This paper describes the control system hardware and software design for these machines.

  6. Future Smart Cooking Machine System Design

    Directory of Open Access Journals (Sweden)

    Dewi Agushinta R.

    2013-11-01

    Full Text Available There are many tools make human task get easier. Cooking has become a basic necessity for human beings, since food is one of basic human needs. Until now, the cooking equipment being used is still a hand tool. However everyone has slightly high activity. The presence of cooking tools that can do the cooking work by itself is now necessary. Future Smart Cooking Machine is an artificial intelligence machine that can do cooking work automatically. With this system design, the time is minimized and the ease of work is expected to be achieved. The development of this system is carried out with System Development Life Cycle (SDLC methods. Prototyping method used in this system is a throw-away prototyping approach. At the end of this research there will be produced a cooking machine system design including physical design engine and interface design.

  7. Superconducting Coil Winding Machine Control System

    Energy Technology Data Exchange (ETDEWEB)

    Nogiec, J. M. [Fermilab; Kotelnikov, S. [Fermilab; Makulski, A. [Fermilab; Walbridge, D. [Fermilab; Trombly-Freytag, K. [Fermilab

    2016-10-05

    The Spirex coil winding machine is used at Fermilab to build coils for superconducting magnets. Recently this ma-chine was equipped with a new control system, which al-lows operation from both a computer and a portable remote control unit. This control system is distributed between three layers, implemented on a PC, real-time target, and FPGA, providing respectively HMI, operational logic and direct controls. The system controls motion of all mechan-ical components and regulates the cable tension. Safety is ensured by a failsafe, redundant system.

  8. Evaluation of Hindi to Punjabi Machine Translation System

    OpenAIRE

    Goyal, Vishal; Lehal, Gurpreet Singh

    2009-01-01

    Machine Translation in India is relatively young. The earliest efforts date from the late 80s and early 90s. The success of every system is judged from its evaluation experimental results. Number of machine translation systems has been started for development but to the best of author knowledge, no high quality system has been completed which can be used in real applications. Recently, Punjabi University, Patiala, India has developed Punjabi to Hindi Machine translation system with high accur...

  9. Electric machine and current source inverter drive system

    Science.gov (United States)

    Hsu, John S

    2014-06-24

    A drive system includes an electric machine and a current source inverter (CSI). This integration of an electric machine and an inverter uses the machine's field excitation coil for not only flux generation in the machine but also for the CSI inductor. This integration of the two technologies, namely the U machine motor and the CSI, opens a new chapter for the component function integration instead of the traditional integration by simply placing separate machine and inverter components in the same housing. Elimination of the CSI inductor adds to the CSI volumetric reduction of the capacitors and the elimination of PMs for the motor further improve the drive system cost, weight, and volume.

  10. Operating System For Numerically Controlled Milling Machine

    Science.gov (United States)

    Ray, R. B.

    1992-01-01

    OPMILL program is operating system for Kearney and Trecker milling machine providing fast easy way to program manufacture of machine parts with IBM-compatible personal computer. Gives machinist "equation plotter" feature, which plots equations that define movements and converts equations to milling-machine-controlling program moving cutter along defined path. System includes tool-manager software handling up to 25 tools and automatically adjusts to account for each tool. Developed on IBM PS/2 computer running DOS 3.3 with 1 MB of random-access memory.

  11. Ground loops detection system in the RFX machine

    International Nuclear Information System (INIS)

    Bellina, F.; Pomaro, N.; Trevisan, F.

    1996-01-01

    RFX is a toroidal machine for the fusion research based on the RFP configuration. During the pulse, in any conductive loop close to the machine very strong currents can be induced, which may damage the diagnostics and the other instrumentation. To avoid loops, the earthing system of the machine is tree-shaped. However, an accidental contact between metallic earthed masses of the machine may give rise to an unwanted loop as well. An automatic system for the detection of ground loops in the earthing system has therefore been developed, which works continuously during shutdown intervals and between pulses. In the paper the design of the detection system is presented, together with the experimental results on prototypes. 4 refs., 3 figs., 1 tab

  12. Framework for man-machine interface design evaluation system considering cognitive factor

    International Nuclear Information System (INIS)

    Itoh, Toru; Sasaki, Kazunori; Yoshikawa, Hidekazu; Takahashi, Makoto; Furuta, Tomihiko.

    1994-01-01

    It is necessary to improve human reliability in order to gain a higher reliability of the total plant system taking an account of development of plant automation and improvement of machine reliability. Therefore, the role of the man-machine system will come to be important. Accordingly, the evaluation of the man-machine system design information is desired in order to solve the mismatch problem between plant information presented by the man-machine system and information required by the operator comprehensively. This paper discusses required functions and software framework for the man-machine interface design evaluation system. The man-machine interface design evaluation system has features to extract the potential matters which are inherent on the design information of man-machine system by simulating the operator behavior, the plant system and the man-machine system, considering the operator's cognitive performance and time dependency. (author)

  13. Slide system for machine tools

    Science.gov (United States)

    Douglass, Spivey S.; Green, Walter L.

    1982-01-01

    The present invention relates to a machine tool which permits the machining of nonaxisymmetric surfaces on a workpiece while rotating the workpiece about a central axis of rotation. The machine tool comprises a conventional two-slide system (X-Y) with one of these slides being provided with a relatively short travel high-speed auxiliary slide which carries the material-removing tool. The auxiliary slide is synchronized with the spindle speed and the position of the other two slides and provides a high-speed reciprocating motion required for the displacement of the cutting tool for generating a nonaxisymmetric surface at a selected location on the workpiece.

  14. Investigation of the Machining Stability of a Milling Machine with Hybrid Guideway Systems

    Directory of Open Access Journals (Sweden)

    Jui-Pin Hung

    2016-03-01

    Full Text Available This study was aimed to investigate the machining stability of a horizontal milling machine with hybrid guideway systems by finite element method. To this purpose, we first created finite element model of the milling machine with the introduction of the contact stiffness defined at the sliding and rolling interfaces, respectively. Also, the motorized built-in spindle model was created and implemented in the whole machine model. Results of finite element simulations reveal that linear guides with different preloads greatly affect the dynamic responses and machining stability of the horizontal milling machine. The critical cutting depth predicted at the vibration mode associated with the machine tool structure is about 10 mm and 25 mm in the X and Y direction, respectively, while the cutting depth predicted at the vibration mode associated with the spindle structure is about 6.0 mm. Also, the machining stability can be increased when the preload of linear roller guides of the feeding mechanism is changed from lower to higher amount.

  15. Positional reference system for ultraprecision machining

    International Nuclear Information System (INIS)

    Arnold, J.B.; Burleson, R.R.; Pardue, R.M.

    1982-01-01

    A stable positional reference system for use in improving the cutting tool-to-part contour position in numerical controlledmultiaxis metal turning machines is provided. The reference system employs a plurality of interferometers referenced to orthogonally disposed metering bars which are substantially isolated from machine strain induced position errors for monitoring the part and tool positions relative to the metering bars. A microprocessor-based control system is employed in conjunction with the plurality of position interferometers and part contour description data inputs to calculate error components for each axis of movement and output them to corresponding axis drives with appropriate scaling and error compensation. Real-time position control, operating in combination with the reference system, makes possible the positioning of the cutting points of a tool along a part locus with a substantially greater degree of accuracy than has been attained previously in the art by referencing and then monitoring only the tool motion relative to a reference position located on the machine base

  16. Positional reference system for ultraprecision machining

    Science.gov (United States)

    Arnold, J.B.; Burleson, R.R.; Pardue, R.M.

    1980-09-12

    A stable positional reference system for use in improving the cutting tool-to-part contour position in numerical controlled-multiaxis metal turning machines is provided. The reference system employs a plurality of interferometers referenced to orthogonally disposed metering bars which are substantially isolated from machine strain induced position errors for monitoring the part and tool positions relative to the metering bars. A microprocessor-based control system is employed in conjunction with the plurality of positions interferometers and part contour description data input to calculate error components for each axis of movement and output them to corresponding axis driven with appropriate scaling and error compensation. Real-time position control, operating in combination with the reference system, makes possible the positioning of the cutting points of a tool along a part locus with a substantially greater degree of accuracy than has been attained previously in the art by referencing and then monitoring only the tool motion relative to a reference position located on the machine base.

  17. Beam interlock system and safe machine parameters system 2010 and beyond

    CERN Document Server

    Todd, B

    2010-01-01

    The Beam Interlock System (BIS) and Safe Machine Parameters (SMP) system are central to the protection of the Large Hadron Collider (LHC) machine. The BIS has been critical for the safe operation of LHC from the first day of operation. It has been installed and commissioned, only minor enhancements are required in order to accommodate all future LHC machine protection requirements. At reduced intensity, the SMP system is less critical for LHC operation. As such, the current system satisfies the 2010 operational requirements. Further developments are required, both at the SMP Controller level, and at the system level, in order to accommodate the requirements of the LHC beyond 2010.

  18. Status Checking System of Home Appliances using machine learning

    Directory of Open Access Journals (Sweden)

    Yoon Chi-Yurl

    2017-01-01

    Full Text Available This paper describes status checking system of home appliances based on machine learning, which can be applied to existing household appliances without networking function. Designed status checking system consists of sensor modules, a wireless communication module, cloud server, android application and a machine learning algorithm. The developed system applied to washing machine analyses and judges the four-kinds of appliance’s status such as staying, washing, rinsing and spin-drying. The measurements of sensor and transmission of sensing data are operated on an Arduino board and the data are transmitted to cloud server in real time. The collected data are parsed by an Android application and injected into the machine learning algorithm for learning the status of the appliances. The machine learning algorithm compares the stored learning data with collected real-time data from the appliances. Our results are expected to contribute as a base technology to design an automatic control system based on machine learning technology for household appliances in real-time.

  19. A strategy for man-machine system development in process industries

    International Nuclear Information System (INIS)

    Wirstad, J.

    1986-12-01

    A framework for Man-Machine System design in process industry projects is reported. It is based in the Guidelines for the Design of Man-Machine interfaces which have been generated in cooperation within the European Workshop for Industrial Computer Systems (EWICS). The application of EWICS Guidelines in industrial projects is demonstrated by six User Scenarios, which represent typical projects from different industries, e.g. electrical power generation and distribution, water control, pulp and paper production, oil and gas production. In all these projects Man-Machine System design has been conducted. It is recommended in the report that each Company develops its set of Man-Machine Systems Standard techniques/procedures. At present there are several techniques/procedures available which, for moderate costs, can be adapted to specific Company conditions. A menu of such Man-Machine System techniques/procedures is presented. Means of estimating the costs and benefits of Man-Machine System design are also described. (author)

  20. WWER NPPs fuel handling machine control system

    International Nuclear Information System (INIS)

    Mini, G.; Rossi, G.; Barabino, M.; Casalini, M.

    2001-01-01

    In order to increase the safety level of the fuel handling machine on WWER NPPs, Ansaldo Nucleare was asked to design and supply a new Control System. Two FHM Control System units have been already supplied for Temelin NPP and others supplies are in process for the Atommash company, which has in charge the supply of FHMs for NPPs located in Russia, Ukraine and China. The Fuel Handling Machine (FHM) Control System is an integrated system capable of a complete management of nuclear fuel assemblies. The computer-based system takes into account all the operational safety interlocks so that it is able to avoid incorrect and dangerous manoeuvres in the case of operator error. Control system design criteria, hardware and software architecture, and quality assurance control, are in accordance with the most recent international requirements and standards, and in particular for electromagnetic disturbance immunity demands and seismic compatibility. The hardware architecture of the control system is based on ABB INFI 90 system. The microprocessor-based ABB INFI 90 system incorporates and improves upon many of the time proven control capabilities of Bailey Network 90, validated over 14,000 installations world-wide. The control system complies all the former designed sensors and devices of the machine and markedly the angular position measurement sensors named 'selsyn' of Russian design. Nevertheless it is fully compatible with all the most recent sensors and devices currently available on the market (for ex. Multiturn absolute encoders). All control logic components were developed using standard INFI 90 Engineering Work Station, interconnecting blocks extracted from an extensive SAMA library by using a graphical approach (CAD) and allowing an easier intelligibility, more flexibility and updated and coherent documentation. The data acquisition system and the Man Machine Interface are implemented by ABB in co-operation with Ansaldo. The flexible and powerful software structure

  1. Improving the reliability of stator insulation system in rotating machines

    International Nuclear Information System (INIS)

    Gupta, G.K.; Sedding, H.G.; Culbert, I.M.

    1997-01-01

    Reliable performance of rotating machines, especially generators and primary heat transport pump motors, is critical to the efficient operation on nuclear stations. A significant number of premature machine failures have been attributed to the stator insulation problems. Ontario Hydro has attempted to assure the long term reliability of the insulation system in critical rotating machines through proper specifications and quality assurance tests for new machines and periodic on-line and off-line diagnostic tests on machines in service. The experience gained over the last twenty years is presented in this paper. Functional specifications have been developed for the insulation system in critical rotating machines based on engineering considerations and our past experience. These specifications include insulation stress, insulation resistance and polarization index, partial discharge levels, dissipation factor and tip up, AC and DC hipot tests. Voltage endurance tests are specified for groundwall insulation system of full size production coils and bars. For machines with multi-turn coils, turn insulation strength for fast fronted surges in specified and verified through tests on all coils in the factory and on samples of finished coils in the laboratory. Periodic on-line and off-line diagnostic tests were performed to assess the condition of the stator insulation system in machines in service. Partial discharges are measured on-line using several techniques to detect any excessive degradation of the insulation system in critical machines. Novel sensors have been developed and installed in several machines to facilitate measurements of partial discharges on operating machines. Several off-line tests are performed either to confirm the problems indicated by the on-line test or to assess the insulation system in machines which cannot be easily tested on-line. Experience with these tests, including their capabilities and limitations, are presented. (author)

  2. Recent developments in man-machine systems

    International Nuclear Information System (INIS)

    Johannsen, G.

    1987-01-01

    The field of man-machine systems is introduced with its subareas and a short outline of its history of 45 years. Three current lines of development in university and industrial research are emphasized. Today, the human problem solving activities are experimentally investigated and analytically described more vigorously than the control activities. Further, improved information presentations and decision support are made possible through new technologies of computer graphics and expert systems. At last, work on a general design methodology for man-machine systems is in progress. The aim is to better support human operators of dynamic technological systems as well as designers of graphics for visual display units and of dialogue styles. Thereby, safety and availability of the complete system can be increased. (orig.) [de

  3. Reinforcement and Systemic Machine Learning for Decision Making

    CERN Document Server

    Kulkarni, Parag

    2012-01-01

    Reinforcement and Systemic Machine Learning for Decision Making There are always difficulties in making machines that learn from experience. Complete information is not always available-or it becomes available in bits and pieces over a period of time. With respect to systemic learning, there is a need to understand the impact of decisions and actions on a system over that period of time. This book takes a holistic approach to addressing that need and presents a new paradigm-creating new learning applications and, ultimately, more intelligent machines. The first book of its kind in this new an

  4. Design of Control System for Kiwifruit Automatic Grading Machine

    Directory of Open Access Journals (Sweden)

    Xingjian Zuo

    2013-05-01

    Full Text Available The kiwifruit automatic grading machine is an important machine for postharvest processing of kiwifruit, and the control system ensures that the machine realizes intelligence. The control system for the kiwifruit automatic grading machine designed in this paper comprises a host computer and a slave microcontroller. The host computer provides a visual grading interface for the machine with a LabVIEW software, the slave microcontroller adopts an STC89C52 microcontroller as its core, and C language is used to write programs for controlling a position sensor module, push-pull type electromagnets, motor driving modules and a power supply for controlling the operation of the machine as well as the rise or descend of grading baffle plates. The ideal control effect is obtained through test, and the intelligent operation of the machine is realized.

  5. Building machine learning systems with Python

    CERN Document Server

    Richert, Willi

    2013-01-01

    This is a tutorial-driven and practical, but well-grounded book showcasing good Machine Learning practices. There will be an emphasis on using existing technologies instead of showing how to write your own implementations of algorithms. This book is a scenario-based, example-driven tutorial. By the end of the book you will have learnt critical aspects of Machine Learning Python projects and experienced the power of ML-based systems by actually working on them.This book primarily targets Python developers who want to learn about and build Machine Learning into their projects, or who want to pro

  6. VVER NPPs fuel handling machine control system

    International Nuclear Information System (INIS)

    Mini, G.; Rossi, G.; Barabino, M.; Casalini, M.

    2002-01-01

    In order to increase the safety level of the fuel handling machine on WWER NPPs, Ansaldo Nucleare was asked to design and supply a new Control System. Two Fuel Handling Machine (FHM) Control System units have been already supplied for Temelin NPP and others supply are in process for the Atommash company, which has in charge the supply of FHMs for NPPs located in Russia, Ukraine and China.The computer-based system takes into account all the operational safety interlocks so that it is able to avoid incorrect and dangerous manoeuvres in the case of operator error. Control system design criteria, hardware and software architecture, and quality assurance control, are in accordance with the most recent international requirements and standards, and in particular for electromagnetic disturbance immunity demands and seismic compatibility. The hardware architecture of the control system is based on ABB INFI 90 system. The microprocessor-based ABB INFI 90 system incorporates and improves upon many of the time proven control capabilities of Bailey Network 90, validated over 14,000 installations world-wide.The control system complies all the former designed sensors and devices of the machine and markedly the angular position measurement sensors named 'selsyn' of Russian design. Nevertheless it is fully compatible with all the most recent sensors and devices currently available on the market (for ex. Multiturn absolute encoders).All control logic were developed using standard INFI 90 Engineering Work Station, interconnecting blocks extracted from an extensive SAMA library by using a graphical approach (CAD) and allowing and easier intelligibility, more flexibility and updated and coherent documentation. The data acquisition system and the Man Machine Interface are implemented by ABB in co-operation with Ansaldo. The flexible and powerful software structure of 1090 Work-stations (APMS - Advanced Plant Monitoring System, or Tenore NT) has been successfully used to interface the

  7. Design and Construction of Wireless Control System for Drilling Machine

    Directory of Open Access Journals (Sweden)

    Nang Su Moan Hsam

    2015-06-01

    Full Text Available Abstract Drilling machine is used for boring holes in various materials and used in woodworking metalworking construction and do-it-yourself projects. When the machine operate for a long time the temperature increases and so we need to control the temperature of the machine and some lubrication system need to apply to reduce the temperature. Due to the improvement of technology the system can be controlled with wireless network. This control system use Window Communication Foundation WCF which is the latest service oriented technology to control all drilling machines in industries simultaneously. All drilling machines are start working when they received command from server. After the machine is running for a long time the temperature is gradually increased. This system used LM35 temperature sensor to measure the temperature. When the temperature is over the safely level that is programmed in host server the controller at the server will command to control the speed of motor and applying some lubrication system at the tip and edges of drill. The command from the server is received by the client and sends to PIC. In this control system PIC microcontroller is used as an interface between the client computer and the machine. The speed of motor is controlled with PWM and water pump system is used for lubrication. This control system is designed and simulated with 12V DC motor LM35 sensor LCD displayand relay which is to open the water container to spray water between drill and work piece. The host server choosing to control the drilling machine that are overheat by selecting the clients IP address that is connected with that machine.

  8. Using Expert Systems in Evaluation of the State of High Voltage Machine Insulation Systems

    Directory of Open Access Journals (Sweden)

    K. Záliš

    2000-01-01

    Full Text Available Expert systems are used for evaluating the actual state and future behavior of insulating systems of high voltage electrical machines and equipment. Several rule-based expert systems have been developed in cooperation with top diagnostic workplaces in the Czech Republic for this purpose. The IZOLEX expert system evaluates diagnostic measurement data from commonly used offline diagnostic methods for the diagnostic of high voltage insulation of rotating machines, non-rotating machines and insulating oils. The CVEX expert system evaluates the discharge activity on high voltage electrical machines and equipment by means of an off-line measurement. The CVEXON expert system is for evaluating the discharge activity by on-line measurement, and the ALTONEX expert system is the expert system for on-line monitoring of rotating machines. These developed expert systems are also used for educating students (in bachelor, master and post-graduate studies and in courses which are organized for practicing engineers and technicians and for specialists in the electrical power engineering branch. A complex project has recently been set up to evaluate the measurement of partial discharges. Two parallel expert systems for evaluating partial dischatge activity on high voltage electrical machines will work at the same time in this complex evaluating system.

  9. Water spray ventilator system for continuous mining machines

    Science.gov (United States)

    Page, Steven J.; Mal, Thomas

    1995-01-01

    The invention relates to a water spray ventilator system mounted on a continuous mining machine to streamline airflow and provide effective face ventilation of both respirable dust and methane in underground coal mines. This system has two side spray nozzles mounted one on each side of the mining machine and six spray nozzles disposed on a manifold mounted to the underside of the machine boom. The six spray nozzles are angularly and laterally oriented on the manifold so as to provide non-overlapping spray patterns along the length of the cutter drum.

  10. High slot utilization systems for electric machines

    Science.gov (United States)

    Hsu, John S

    2009-06-23

    Two new High Slot Utilization (HSU) Systems for electric machines enable the use of form wound coils that have the highest fill factor and the best use of magnetic materials. The epoxy/resin/curing treatment ensures the mechanical strength of the assembly of teeth, core, and coils. In addition, the first HSU system allows the coil layers to be moved inside the slots for the assembly purpose. The second system uses the slided-in teeth instead of the plugged-in teeth. The power density of the electric machine that uses either system can reach its highest limit.

  11. Integrated human-machine intelligence in space systems

    Science.gov (United States)

    Boy, Guy A.

    1992-01-01

    The integration of human and machine intelligence in space systems is outlined with respect to the contributions of artificial intelligence. The current state-of-the-art in intelligent assistant systems (IASs) is reviewed, and the requirements of some real-world applications of the technologies are discussed. A concept of integrated human-machine intelligence is examined in the contexts of: (1) interactive systems that tolerate human errors; (2) systems for the relief of workloads; and (3) interactive systems for solving problems in abnormal situations. Key issues in the development of IASs include the compatibility of the systems with astronauts in terms of inputs/outputs, processing, real-time AI, and knowledge-based system validation. Real-world applications are suggested such as the diagnosis, planning, and control of enginnered systems.

  12. Interlock system of electron beam machine GJ-2

    International Nuclear Information System (INIS)

    Marnada, Nada

    1999-01-01

    As an irradiation installation facility, the electron beam machine (EBM) irradiation facility which use radionuclide as radiation source. There are three safety aspects to be considered in the facility i.e the safeties for human, machines, and samples to be irradiated. The safety aspect for human is to the radiation hazard and the safety aspect for machine and sample is to the damage as the result of operating failure. In the EBM GJ-2 (made in China) twelve interlock system parameter are installed to keep all of the safety aspects. Each interlock system consist transducer that controls a certain switch, a magnetic relay, and visible and audible interlock indicators to improve the reliability of interlock systems a method called redundancy method is applied to the systems of operation of high voltage. (author)

  13. Basic researches for advancement of man-machine systems

    International Nuclear Information System (INIS)

    Yoshikawa, Hidekazu

    1994-01-01

    The historical development of plant instrumentation and control system accompanying the introduction of automation is shown by the example of nuclear power plants. It is explained, and the change in the role of operators in the man-machine system is mentioned. Human errors are the serious problem in various fields, and automation resolves it. But complex systems also caused various disasters due to the relation of men and machines. The problem of human factors in high risk system automation is considered as the heightening of reliability and the reduction of burden on workers by decreasing human participation, and the increase of the risk of large accidents due to the lowering of reliability of human elements and the strengthening of the training of workers. Human model and the framework of human error analysis, the development of the system for man-machine system design and information analysis and evaluation, the significance of physiological index measurement and the perspective of the application, the analysis of the behavior of subjects in the abnormality diagnosis experiment using a plant simulator, and the development to the research on mutual adaptation interface are discussed. In this paper, the problem of human factors in system safety, that technical advancement brings about is examined, and the basic research on the advancement of man-machine systems by the author is reported. (K.I.)

  14. Machine and plasma diagnostic instrumentation systems for the Tandem Mirror Experiment Upgrade

    International Nuclear Information System (INIS)

    Coutts, G.W.; Coffield, F.E.; Lang, D.D.; Hornady, R.S.

    1981-01-01

    To evaluate performance of a second generation Tandem Mirror Machine, an extensive instrumentation system is being designed and installed as part of the major device fabrication. The systems listed will be operational during the start-up phase of the TMX Upgrade machine and provide bench marks for future performance data. In addition to plasma diagnostic instrumentation, machine parameter monitoring systems will be installed prior to machine operation. Simultaneous recording of machine parameters will permit evaluation of plasma parameters sensitive to machine conditions

  15. 13th International Conference on Man-Machine-Environment System Engineering

    CERN Document Server

    Dhillon, Balbir

    2014-01-01

    The integrated and advanced science research topic Man-Machine-Environment System Engineering (MMESE) was first established in China by Professor Shengzhao Long in 1981, with direct support from one of the greatest modern Chinese scientists, Xuesen Qian. In a letter to Shengzhao Long from October 22nd, 1993, Xuesen Qian wrote: “You have created a very important modern science and technology in China!”   MMESE primarily focuses on the relationship between man, machines and the environment, studying the optimum combination of man-machine-environment systems. In this system, “man” refers to people in the workplace (e.g. operators, decision-makers); “ machine” is the general name for any object controlled by man (including tools, machinery, computers, systems and technologies), and “environment” describes the specific working conditions under which man and machine interact (e.g. temperature, noise, vibration, hazardous gases etc.). The three goals of optimization of Man-Machine-Environment system...

  16. 14th International Conference on Man-Machine-Environment System Engineering

    CERN Document Server

    Dhillon, Balbir

    2015-01-01

    The integrated and advanced science research topic man-machine-environment system engineering (MMESE) was first established in China by Professor Shengzhao Long in 1981, with direct support from one of the greatest modern Chinese scientists, Xuesen Qian. In a letter to Shengzhao Long from October 22nd, 1993, Xuesen Qian wrote: “You have created a very important modern science and technology in China!”   MMESE primarily focuses on the relationship between man, machines and the environment, studying the optimum combination of man-machine-environment systems. In this system, “man” refers to people in the workplace (e.g. operators, decision-makers); “ machine” is the general name for any object controlled by man (including tools, machinery, computers, systems and technologies), and “environment” describes the specific working conditions under which man and machine interact (e.g. temperature, noise, vibration, hazardous gases etc.). The three goals of optimization of man-machine-environment system...

  17. MiYA, an efficient machine-learning workflow in conjunction with the YeastFab assembly strategy for combinatorial optimization of heterologous metabolic pathways in Saccharomyces cerevisiae.

    Science.gov (United States)

    Zhou, Yikang; Li, Gang; Dong, Junkai; Xing, Xin-Hui; Dai, Junbiao; Zhang, Chong

    2018-05-01

    Facing boosting ability to construct combinatorial metabolic pathways, how to search the metabolic sweet spot has become the rate-limiting step. We here reported an efficient Machine-learning workflow in conjunction with YeastFab Assembly strategy (MiYA) for combinatorial optimizing the large biosynthetic genotypic space of heterologous metabolic pathways in Saccharomyces cerevisiae. Using β-carotene biosynthetic pathway as example, we first demonstrated that MiYA has the power to search only a small fraction (2-5%) of combinatorial space to precisely tune the expression level of each gene with a machine-learning algorithm of an artificial neural network (ANN) ensemble to avoid over-fitting problem when dealing with a small number of training samples. We then applied MiYA to improve the biosynthesis of violacein. Feed with initial data from a colorimetric plate-based, pre-screened pool of 24 strains producing violacein, MiYA successfully predicted, and verified experimentally, the existence of a strain that showed a 2.42-fold titer improvement in violacein production among 3125 possible designs. Furthermore, MiYA was able to largely avoid the branch pathway of violacein biosynthesis that makes deoxyviolacein, and produces very pure violacein. Together, MiYA combines the advantages of standardized building blocks and machine learning to accelerate the Design-Build-Test-Learn (DBTL) cycle for combinatorial optimization of metabolic pathways, which could significantly accelerate the development of microbial cell factories. Copyright © 2018 International Metabolic Engineering Society. Published by Elsevier Inc. All rights reserved.

  18. Machine learning paradigms applications in recommender systems

    CERN Document Server

    Lampropoulos, Aristomenis S

    2015-01-01

    This timely book presents Applications in Recommender Systems which are making recommendations using machine learning algorithms trained via examples of content the user likes or dislikes. Recommender systems built on the assumption of availability of both positive and negative examples do not perform well when negative examples are rare. It is exactly this problem that the authors address in the monograph at hand. Specifically, the books approach is based on one-class classification methodologies that have been appearing in recent machine learning research. The blending of recommender systems and one-class classification provides a new very fertile field for research, innovation and development with potential applications in “big data” as well as “sparse data” problems. The book will be useful to researchers, practitioners and graduate students dealing with problems of extensive and complex data. It is intended for both the expert/researcher in the fields of Pattern Recognition, Machine Learning and ...

  19. Improvement of human operator vibroprotection system in the utility machine

    Science.gov (United States)

    Korchagin, P. A.; Teterina, I. A.; Rahuba, L. F.

    2018-01-01

    The article is devoted to an urgent problem of improving efficiency of road-building utility machines in terms of improving human operator vibroprotection system by determining acceptable values of the rigidity coefficients and resistance coefficients of operator’s cab suspension system elements and those of operator’s seat. Negative effects of vibration result in labour productivity decrease and occupational diseases. Besides, structure vibrations have a damaging impact on the machine units and mechanisms, which leads to reducing an overall service life of the machine. Results of experimental and theoretical research of operator vibroprotection system in the road-building utility machine are presented. An algorithm for the program to calculate dynamic impacts on the operator in terms of different structural and performance parameters of the machine and considering combination of external pertrubation influences was proposed.

  20. An Interactive Web-based Learning System for Assisting Machining Technology Education

    Directory of Open Access Journals (Sweden)

    Min Jou

    2008-05-01

    Full Text Available The key technique of manufacturing methods is machining. The degree of technique of machining directly affects the quality of the product. Therefore, the machining technique is of primary importance in promoting student practice ability during the training process. Currently, practical training is applied in shop floor to discipline student’s practice ability. Much time and cost are used to teach these techniques. Particularly, computerized machines are continuously increasing in use. The development of educating engineers on computerized machines becomes much more difficult than with traditional machines. This is because of the limitation of the extremely expensive cost of teaching. The quality and quantity of teaching cannot always be promoted in this respect. The traditional teaching methods can not respond well to the needs of the future. Therefore, this research aims to the following topics; (1.Propose the teaching strategies for the students to learning machining processing planning through web-based learning system. (2.Establish on-line teaching material for the computer-aided manufacturing courses including CNC coding method, CNC simulation. (3.Develop the virtual machining laboratory to bring the machining practical training to web-based learning system. (4.Integrate multi-media and virtual laboratory in the developed e-learning web-based system to enhance the effectiveness of machining education through web-based system.

  1. Automated reasoning in man-machine control systems

    International Nuclear Information System (INIS)

    Stratton, R.C.; Lusk, E.L.

    1983-01-01

    This paper describes a project being undertaken at Argonne National Laboratory to demonstrate the usefulness of automated reasoning techniques in the implementation of a man-machine control system being designed at the EBR-II nuclear power plant. It is shown how automated reasoning influences the choice of optimal roles for both man and machine in the system control process, both for normal and off-normal operation. In addition, the requirements imposed by such a system for a rigorously formal specification of operating states, subsystem states, and transition procedures have a useful impact on the analysis phase. The definitions and rules are discussed for a prototype system which is physically simple yet illustrates some of the complexities inherent in real systems

  2. A supervisor system for computer aided laser machining

    International Nuclear Information System (INIS)

    Mukherjee, J.K.

    1990-01-01

    Lasers achieve non divergent beam of short wavelength energy which can propagate through normal atmosphere with little divergence and can be focused on very fine points. The final high energy per unit area on target is highly localised and suitable for various types of machining at high speeds. The most notable factor is that this high energy spot can be located precisely using light-weight optical components. The laser-machining is very amenable to environmental conditions unlike electron beam and other techniques. Precision cutting and welding of nuclear materials in normal or non oxidising atmosphere can be done using this fairly easily. To achieve these objectives, development of a computer controlled laser machining system has been undertaken. The development project aims at building a computer aided machine with indegenous controller and medium power laser suitable for cutting, welding, and marking. This paper describes the integration of the various computer aided functions, spanning over the full range, from job-defining to final finished part-delivary, in computer aided laser machining. Various innovative features of the system that render it suitable for laser tool development as well as for special machining applications with user-friendliness have been covered. (author). 5 refs., 5 figs

  3. Man-machine interfaces analysis system based on computer simulation

    International Nuclear Information System (INIS)

    Chen Xiaoming; Gao Zuying; Zhou Zhiwei; Zhao Bingquan

    2004-01-01

    The paper depicts a software assessment system, Dynamic Interaction Analysis Support (DIAS), based on computer simulation technology for man-machine interfaces (MMI) of a control room. It employs a computer to simulate the operation procedures of operations on man-machine interfaces in a control room, provides quantified assessment, and at the same time carries out analysis on operational error rate of operators by means of techniques for human error rate prediction. The problems of placing man-machine interfaces in a control room and of arranging instruments can be detected from simulation results. DIAS system can provide good technical supports to the design and improvement of man-machine interfaces of the main control room of a nuclear power plant

  4. MODELING AND INVESTIGATION OF ASYNCHRONOUS TWO-MACHINE SYSTEM MODES

    Directory of Open Access Journals (Sweden)

    V. S. Safaryan

    2014-01-01

    Full Text Available The paper considers stationary and transient processes of an asynchronous two-machine system. A mathematical model for investigation of stationary and transient modes, static characteristics and research results of dynamic process pertaining to starting-up the asynchronous two-machine system has been given in paper.

  5. High-precision micro/nano-scale machining system

    Science.gov (United States)

    Kapoor, Shiv G.; Bourne, Keith Allen; DeVor, Richard E.

    2014-08-19

    A high precision micro/nanoscale machining system. A multi-axis movement machine provides relative movement along multiple axes between a workpiece and a tool holder. A cutting tool is disposed on a flexible cantilever held by the tool holder, the tool holder being movable to provide at least two of the axes to set the angle and distance of the cutting tool relative to the workpiece. A feedback control system uses measurement of deflection of the cantilever during cutting to maintain a desired cantilever deflection and hence a desired load on the cutting tool.

  6. The laser micro-machining system for diamond anvil cell experiments and general precision machining applications at the High Pressure Collaborative Access Team.

    Science.gov (United States)

    Hrubiak, Rostislav; Sinogeikin, Stanislav; Rod, Eric; Shen, Guoyin

    2015-07-01

    We have designed and constructed a new system for micro-machining parts and sample assemblies used for diamond anvil cells and general user operations at the High Pressure Collaborative Access Team, sector 16 of the Advanced Photon Source. The new micro-machining system uses a pulsed laser of 400 ps pulse duration, ablating various materials without thermal melting, thus leaving a clean edge. With optics designed for a tight focus, the system can machine holes any size larger than 3 μm in diameter. Unlike a standard electrical discharge machining drill, the new laser system allows micro-machining of non-conductive materials such as: amorphous boron and silicon carbide gaskets, diamond, oxides, and other materials including organic materials such as polyimide films (i.e., Kapton). An important feature of the new system is the use of gas-tight or gas-flow environmental chambers which allow the laser micro-machining to be done in a controlled (e.g., inert gas) atmosphere to prevent oxidation and other chemical reactions in air sensitive materials. The gas-tight workpiece enclosure is also useful for machining materials with known health risks (e.g., beryllium). Specialized control software with a graphical interface enables micro-machining of custom 2D and 3D shapes. The laser-machining system was designed in a Class 1 laser enclosure, i.e., it includes laser safety interlocks and computer controls and allows for routine operation. Though initially designed mainly for machining of the diamond anvil cell gaskets, the laser-machining system has since found many other micro-machining applications, several of which are presented here.

  7. The laser micro-machining system for diamond anvil cell experiments and general precision machining applications at the High Pressure Collaborative Access Team

    International Nuclear Information System (INIS)

    Hrubiak, Rostislav; Sinogeikin, Stanislav; Rod, Eric; Shen, Guoyin

    2015-01-01

    We have designed and constructed a new system for micro-machining parts and sample assemblies used for diamond anvil cells and general user operations at the High Pressure Collaborative Access Team, sector 16 of the Advanced Photon Source. The new micro-machining system uses a pulsed laser of 400 ps pulse duration, ablating various materials without thermal melting, thus leaving a clean edge. With optics designed for a tight focus, the system can machine holes any size larger than 3 μm in diameter. Unlike a standard electrical discharge machining drill, the new laser system allows micro-machining of non-conductive materials such as: amorphous boron and silicon carbide gaskets, diamond, oxides, and other materials including organic materials such as polyimide films (i.e., Kapton). An important feature of the new system is the use of gas-tight or gas-flow environmental chambers which allow the laser micro-machining to be done in a controlled (e.g., inert gas) atmosphere to prevent oxidation and other chemical reactions in air sensitive materials. The gas-tight workpiece enclosure is also useful for machining materials with known health risks (e.g., beryllium). Specialized control software with a graphical interface enables micro-machining of custom 2D and 3D shapes. The laser-machining system was designed in a Class 1 laser enclosure, i.e., it includes laser safety interlocks and computer controls and allows for routine operation. Though initially designed mainly for machining of the diamond anvil cell gaskets, the laser-machining system has since found many other micro-machining applications, several of which are presented here

  8. EAST machine assembly and its measurement system

    International Nuclear Information System (INIS)

    Wu, S.T.

    2005-01-01

    The EAST (HT-7U) superconducting tokamak consists of a superconducting poloidal field magnet system, a toroidal field magnet system, a vacuum vessel and in-vessel components, thermal shields and a cryostat vessel. The main parts of the machine have been delivered to ASIPP (Institute of Plasma Physics, Chinese Academy of Sciences) successionally from 2003. For its complicated constitution and precise requirement, a reasonable assembly procedure and measurement technique should be defined carefully. Before the assembly procedure, a reference frame has been set up with reference fiducial targets on the wall of the test hall by an industrial measurement system. After the torus of TF coils is formed, a new reference frame will be set up from the position of the TF torus. The vacuum vessel with all inner parts will be installed with reference of the new reference frame. The big size and mass of components, special configuration of the superconducting machine with tight installation tolerances of the HT-7U (EAST) machine result in complicated assembly procedure. The procedure had begun with the installation of the support frame and the base of cryostat vessel last year. In this paper, the requirements of the assembly precise for some key components of the machine are described. The reference frame for the assembly and maintenance is explained. The assembly procedure is introduced

  9. A modeling method for hybrid energy behaviors in flexible machining systems

    International Nuclear Information System (INIS)

    Li, Yufeng; He, Yan; Wang, Yan; Wang, Yulin; Yan, Ping; Lin, Shenlong

    2015-01-01

    Increasingly environmental and economic pressures have led to great concerns regarding the energy consumption of machining systems. Understanding energy behaviors of flexible machining systems is a prerequisite for improving energy efficiency of these systems. This paper proposes a modeling method to predict energy behaviors in flexible machining systems. The hybrid energy behaviors not only depend on the technical specification related of machine tools and workpieces, but are significantly affected by individual production scenarios. In the method, hybrid energy behaviors are decomposed into Structure-related energy behaviors, State-related energy behaviors, Process-related energy behaviors and Assignment-related energy behaviors. The modeling method for the hybrid energy behaviors is proposed based on Colored Timed Object-oriented Petri Net (CTOPN). The former two types of energy behaviors are modeled by constructing the structure of CTOPN, whist the latter two types of behaviors are simulated by applying colored tokens and associated attributes. Machining on two workpieces in the experimental workshop were undertaken to verify the proposed modeling method. The results showed that the method can provide multi-perspective transparency on energy consumption related to machine tools, workpieces as well as production management, and is particularly suitable for flexible manufacturing system when frequent changes in machining systems are often encountered. - Highlights: • Energy behaviors in flexible machining systems are modeled in this paper. • Hybrid characteristics of energy behaviors are examined from multiple viewpoints. • Flexible modeling method CTOPN is used to predict the hybrid energy behaviors. • This work offers a multi-perspective transparency on energy consumption

  10. Technique for Increasing Accuracy of Positioning System of Machine Tools

    Directory of Open Access Journals (Sweden)

    Sh. Ji

    2014-01-01

    Full Text Available The aim of research is to improve the accuracy of positioning and processing system using a technique for optimization of pressure diagrams of guides in machine tools. The machining quality is directly related to its accuracy, which characterizes an impact degree of various errors of machines. The accuracy of the positioning system is one of the most significant machining characteristics, which allow accuracy evaluation of processed parts.The literature describes that the working area of the machine layout is rather informative to characterize the effect of the positioning system on the macro-geometry of the part surfaces to be processed. To enhance the static accuracy of the studied machine, in principle, two groups of measures are possible. One of them points toward a decrease of the cutting force component, which overturns the slider moments. Another group of measures is related to the changing sizes of the guide facets, which may lead to their profile change.The study was based on mathematical modeling and optimization of the cutting zone coordinates. And we find the formula to determine the surface pressure of the guides. The selected parameters of optimization are vectors of the cutting force and values of slides and guides. Obtained results show that a technique for optimization of coordinates in the cutting zone was necessary to increase a processing accuracy.The research has established that to define the optimal coordinates of the cutting zone we have to change the sizes of slides, value and coordinates of applied forces, reaching the pressure equalization and improving the accuracy of positioning system of machine tools. In different points of the workspace a vector of forces is applied, pressure diagrams are found, which take into account the changes in the parameters of positioning system, and the pressure diagram equalization to provide the most accuracy of machine tools is achieved.

  11. Discrete Model Reference Adaptive Control System for Automatic Profiling Machine

    Directory of Open Access Journals (Sweden)

    Peng Song

    2012-01-01

    Full Text Available Automatic profiling machine is a movement system that has a high degree of parameter variation and high frequency of transient process, and it requires an accurate control in time. In this paper, the discrete model reference adaptive control system of automatic profiling machine is discussed. Firstly, the model of automatic profiling machine is presented according to the parameters of DC motor. Then the design of the discrete model reference adaptive control is proposed, and the control rules are proven. The results of simulation show that adaptive control system has favorable dynamic performances.

  12. System design for the new TMX machine

    International Nuclear Information System (INIS)

    Chargin, A.K.; Calderon, M.O.; Mooney, L.J.; Vogtlin, G.E.

    1977-01-01

    The Tandem Mirror Experiment (TMX) is designed to test the physics of a new approach to Q-enhancement in open confinement systems. In the tandem mirror concept, the ends of a long solenoid are plugged electrostatically by means of ambipolar potential barriers created in two mirror machines or plugs, one at each end of the solenoid. The ambipolar potential in mirror machines develops as a consequence of the higher scattering rate of electrons and the balancing of electron and ion loss rates. The TMX experiment incorporates very few new engineering developments, but it does involve a new way of combining in an integrated system many previously developed ideas. The engineering task is to design the machine that would provide a proof-of-principle evaluation of the tandem mirror concept as rapidly as possible. The preliminary design was started in September 1976 and was completed by December 1976. It led to a cost estimate of $11 million and a scheduled construction period of 18 months

  13. Shape understanding system machine understanding and human understanding

    CERN Document Server

    Les, Zbigniew

    2015-01-01

    This is the third book presenting selected results of research on the further development of the shape understanding system (SUS) carried out by authors in the newly founded Queen Jadwiga Research Institute of Understanding. In this book the new term Machine Understanding is introduced referring to a new area of research aiming to investigate the possibility of building machines with the ability to understand. It is presented that SUS needs to some extent mimic human understanding and for this reason machines are evaluated according to the rules applied for the evaluation of human understanding. The book shows how to formulate problems and how it can be tested if the machine is able to solve these problems.    

  14. Machine vision system for measuring conifer seedling morphology

    Science.gov (United States)

    Rigney, Michael P.; Kranzler, Glenn A.

    1995-01-01

    A PC-based machine vision system providing rapid measurement of bare-root tree seedling morphological features has been designed. The system uses backlighting and a 2048-pixel line- scan camera to acquire images with transverse resolutions as high as 0.05 mm for precise measurement of stem diameter. Individual seedlings are manually loaded on a conveyor belt and inspected by the vision system in less than 0.25 seconds. Designed for quality control and morphological data acquisition by nursery personnel, the system provides a user-friendly, menu-driven graphical interface. The system automatically locates the seedling root collar and measures stem diameter, shoot height, sturdiness ratio, root mass length, projected shoot and root area, shoot-root area ratio, and percent fine roots. Sample statistics are computed for each measured feature. Measurements for each seedling may be stored for later analysis. Feature measurements may be compared with multi-class quality criteria to determine sample quality or to perform multi-class sorting. Statistical summary and classification reports may be printed to facilitate the communication of quality concerns with grading personnel. Tests were conducted at a commercial forest nursery to evaluate measurement precision. Four quality control personnel measured root collar diameter, stem height, and root mass length on each of 200 conifer seedlings. The same seedlings were inspected four times by the machine vision system. Machine stem diameter measurement precision was four times greater than that of manual measurements. Machine and manual measurements had comparable precision for shoot height and root mass length.

  15. Machine-Vision Systems Selection for Agricultural Vehicles: A Guide

    Directory of Open Access Journals (Sweden)

    Gonzalo Pajares

    2016-11-01

    Full Text Available Machine vision systems are becoming increasingly common onboard agricultural vehicles (autonomous and non-autonomous for different tasks. This paper provides guidelines for selecting machine-vision systems for optimum performance, considering the adverse conditions on these outdoor environments with high variability on the illumination, irregular terrain conditions or different plant growth states, among others. In this regard, three main topics have been conveniently addressed for the best selection: (a spectral bands (visible and infrared; (b imaging sensors and optical systems (including intrinsic parameters and (c geometric visual system arrangement (considering extrinsic parameters and stereovision systems. A general overview, with detailed description and technical support, is provided for each topic with illustrative examples focused on specific applications in agriculture, although they could be applied in different contexts other than agricultural. A case study is provided as a result of research in the RHEA (Robot Fleets for Highly Effective Agriculture and Forestry Management project for effective weed control in maize fields (wide-rows crops, funded by the European Union, where the machine vision system onboard the autonomous vehicles was the most important part of the full perception system, where machine vision was the most relevant. Details and results about crop row detection, weed patches identification, autonomous vehicle guidance and obstacle detection are provided together with a review of methods and approaches on these topics.

  16. Control system of power supply for resistance welding machine

    Directory of Open Access Journals (Sweden)

    Світлана Костянтинівна Поднебенна

    2017-06-01

    Full Text Available This article describes the existing methods of heat energy stabilizing, which are realized in thyristor power supplies for resistance welding machines. The advantages and features of thyristor power supplies have been described. A control system of power supply for resistance welding machine with stabilization of heat energy in a welding spot has been developed. Measurements are performed in primary winding of a welding transformer. Weld spot heating energy is calculated as the difference between the energy, consumed from the mains, and the energy losses in the primary and secondary circuits of the welding transformer as well as the energy losses in the transformer core. Algorithms of digital signal processing of the developed control system are described in the article. All measurements and calculations are preformed automatically in real-time. Input signals to the control system are: transformer primary voltage and current, temperature of the welding circuit. The designed control system ensures control of the welding heat energy and is not influenced by the supply voltage and impedance changes caused by insertion of the ferromagnetic mass in the welding circuit, the temperature change during the welding process. The developed control system for resistance welding machine makes it possible to improve the quality of welded joints, increase the efficiency of the resistance welding machine

  17. System approach to machine building enterprise innovative activity management

    Directory of Open Access Journals (Sweden)

    І.V. Levytska

    2016-12-01

    Full Text Available The company, which operates in a challenging competitive environment should focus on new products and provide innovative services that enhance their innovation to maintain the company’s market position. The article deals with the peculiarities of such an activity in the company. The authors analyze the various approaches used in the management, and supply the advantages and disadvantages of each. It is determine that the most optimal approach among them is a system approach. The definition of the consepts "a system" and "a systematic approach to innovative activity management" are suggested. The article works out the system of machine building enterprise innovative activity management, the organization of machine building enterprise innovative activity; the planning of machine building enterprise innovative activity; the control in the system of machine building enterprise innovative activity management; the elements of the control subsystem. The properties, typical for the system of innovative management, are supplied. The managers, engaged in enterprise innovative activity management, must perform a number of the suggested tasks, which affect the efficiency of the enterprise as a whole. These exact tasks are performed using the systematic approach, providing the enterprise competitive operation and quick adaptation to changes in the external environment.

  18. Machine Protection and Interlock Systems for Circular Machines - Example for LHC

    CERN Document Server

    Schmidt, R.

    2016-01-01

    This paper introduces the protection of circular particle accelerators from accidental beam losses. Already the energy stored in the beams for accelerators such as the TEVATRON at Fermilab and Super Proton Synchrotron (SPS) at CERN could cause serious damage in case of uncontrolled beam loss. With the CERN Large Hadron Collider (LHC), the energy stored in particle beams has reached a value two orders of magnitude above previous accelerators and poses new threats with respect to hazards from the energy stored in the particle beams. A single accident damaging vital parts of the accelerator could interrupt operation for years. Protection of equipment from beam accidents is mandatory. Designing a machine protection system requires an excellent understanding of accelerator physics and operation to anticipate possible failures that could lead to damage. Machine protection includes beam and equipment monitoring, a system to safely stop beam operation (e.g. extraction of the beam towards a dedicated beam dump block o...

  19. Single-molecule imaging and manipulation of biomolecular machines and systems.

    Science.gov (United States)

    Iino, Ryota; Iida, Tatsuya; Nakamura, Akihiko; Saita, Ei-Ichiro; You, Huijuan; Sako, Yasushi

    2018-02-01

    Biological molecular machines support various activities and behaviors of cells, such as energy production, signal transduction, growth, differentiation, and migration. We provide an overview of single-molecule imaging methods involving both small and large probes used to monitor the dynamic motions of molecular machines in vitro (purified proteins) and in living cells, and single-molecule manipulation methods used to measure the forces, mechanical properties and responses of biomolecules. We also introduce several examples of single-molecule analysis, focusing primarily on motor proteins and signal transduction systems. Single-molecule analysis is a powerful approach to unveil the operational mechanisms both of individual molecular machines and of systems consisting of many molecular machines. Quantitative, high-resolution single-molecule analyses of biomolecular systems at the various hierarchies of life will help to answer our fundamental question: "What is life?" This article is part of a Special Issue entitled "Biophysical Exploration of Dynamical Ordering of Biomolecular Systems" edited by Dr. Koichi Kato. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. 16th International Conference on Man-Machine-Environment System Engineering

    CERN Document Server

    Dhillon, Balbir

    2016-01-01

    This research topic was first established in China by Professor Shengzhao Long in 1981, with direct support from one of the greatest modern Chinese scientists, Xuesen Qian. In a letter to Shengzhao Long from October 22nd, 1993, Xuesen Qian wrote: “You have created a very important modern science subject and technology in China!” MMESE primarily focuses on the relationship between Man, Machine and Environment, studying the optimum combination of man-machine-environment systems. In this system, “Man” refers to working people as the subject in the workplace (e.g. operators, decision-makers); “Machine” is the general name for any object controlled by Man (including tools, machinery, computers, systems and technologies), and “Environment” describes the specific working conditions under which Man and Machine interact (e.g. temperature, noise, vibration, hazardous gases etc.). The three goals of optimization are to ensure "Safety, High efficiency and Economy" of man-machine-environment systems. These...

  1. Modelling and Simulation of a Synchronous Machine with Power Electronic Systems

    DEFF Research Database (Denmark)

    Chen, Zhe; Blaabjerg, Frede

    2005-01-01

    is modelled in SIMULINK as well. The resulting model can more accurately represent non-idea situations such as non-symmetrical parameters of the electrical machines and unbalance conditions. The model may be used for both steady state and large-signal dynamic analysis. This is particularly useful......This paper reports the modeling and simulation of a synchronous machine with a power electronic interface in direct phase model. The implementation of a direct phase model of synchronous machines in MATLAB/SIMULINK is presented .The power electronic system associated with the synchronous machine...... in the systems where a detailed study is needed in order to assess the overall system stability. Simulation studies are performed under various operation conditions. It is shown that the developed model could be used for studies of various applications of synchronous machines such as in renewable and DG...

  2. A Machine Vision System for Automatically Grading Hardwood Lumber - (Proceedings)

    Science.gov (United States)

    Richard W. Conners; Tai-Hoon Cho; Chong T. Ng; Thomas H. Drayer; Joe G. Tront; Philip A. Araman; Robert L. Brisbon

    1990-01-01

    Any automatic system for grading hardwood lumber can conceptually be divided into two components. One of these is a machine vision system for locating and identifying grading defects. The other is an automatic grading program that accepts as input the output of the machine vision system and, based on these data, determines the grade of a board. The progress that has...

  3. An experimental study on a superconducting generator with dual machine shield system

    International Nuclear Information System (INIS)

    Ishigohka, T.; Ninomiya, A.; Okada, T.; Nitta, T.; Shintani, T.; Mukai, E.

    1988-01-01

    The authors have studied the optimal machine shield system through experiments on a 20kVa superconducting generator. The first experiment is carried out on a fully iron-less aluminum-shield machine which has only an aluminum eddy current machine shield in the stator. The second experiment is carried out on a generator with a dual-shield system which has both an aluminum eddy current shield and an iron magnetic shield. From the first one, the authors have got an experimental result that the aluminum-shield machine exhibits so large eddy current loss in the shield that it would be difficult to operate the machine continuously. On the other hand, the second experiment shows that the dual-shield machine exhibits much smaller loss in the shielding system, and that it has higher output power than the aluminum-shield machine. From these experiments, it becomes clear that insertion of a very thin iron shield between the armature winding and the eddy current shield can improve the machine performance eminently without large weight increase even if the iron shield were saturated

  4. TensorFlow: A system for large-scale machine learning

    OpenAIRE

    Abadi, Martín; Barham, Paul; Chen, Jianmin; Chen, Zhifeng; Davis, Andy; Dean, Jeffrey; Devin, Matthieu; Ghemawat, Sanjay; Irving, Geoffrey; Isard, Michael; Kudlur, Manjunath; Levenberg, Josh; Monga, Rajat; Moore, Sherry; Murray, Derek G.

    2016-01-01

    TensorFlow is a machine learning system that operates at large scale and in heterogeneous environments. TensorFlow uses dataflow graphs to represent computation, shared state, and the operations that mutate that state. It maps the nodes of a dataflow graph across many machines in a cluster, and within a machine across multiple computational devices, including multicore CPUs, general-purpose GPUs, and custom designed ASICs known as Tensor Processing Units (TPUs). This architecture gives flexib...

  5. Molecular, metabolic, and genetic control: An introduction

    Science.gov (United States)

    Tyson, John J.; Mackey, Michael C.

    2001-03-01

    The living cell is a miniature, self-reproducing, biochemical machine. Like all machines, it has a power supply, a set of working components that carry out its necessary tasks, and control systems that ensure the proper coordination of these tasks. In this Special Issue, we focus on the molecular regulatory systems that control cell metabolism, gene expression, environmental responses, development, and reproduction. As for the control systems in human-engineered machines, these regulatory networks can be described by nonlinear dynamical equations, for example, ordinary differential equations, reaction-diffusion equations, stochastic differential equations, or cellular automata. The articles collected here illustrate (i) a range of theoretical problems presented by modern concepts of cellular regulation, (ii) some strategies for converting molecular mechanisms into dynamical systems, (iii) some useful mathematical tools for analyzing and simulating these systems, and (iv) the sort of results that derive from serious interplay between theory and experiment.

  6. Theory and practice in machining systems

    CERN Document Server

    Ito, Yoshimi

    2017-01-01

    This book describes machining technology from a wider perspective by considering it within the machining space. Machining technology is one of the metal removal activities that occur at the machining point within the machining space. The machining space consists of structural configuration entities, e.g., the main spindle, the turret head and attachments such the chuck and mandrel, and also the form-generating movement of the machine tool itself. The book describes fundamental topics, including the form-generating movement of the machine tool and the important roles of the attachments, before moving on to consider the supply of raw materials into the machining space, and the discharge of swarf from it, and then machining technology itself. Building on the latest research findings “Theory and Practice in Machining System” discusses current challenges in machining. Thus, with the inclusion of introductory and advanced topics, the book can be used as a guide and survey of machining technology for students an...

  7. Variable-Speed, Robust Synchronous Reluctance Machine Drive Systems

    DEFF Research Database (Denmark)

    Wang, Dong

    The synchronous reluctance machine drive is getting more and more interests from the industrial side, since it can provide higher system energy efficiency than traditional inverter-fed induction machine drive systems with similar production cost. It is considered as a good candidate for super...... is recommended. In recent years, there is an increasing trend to replace the electrolytic capacitor in the frequency converter with film capacitor, which has a longer expected service lifetime and no explosion risk. Furthermore, it is possible to achieve a compact converter design by using film capacitor, since...

  8. Bionic machines and systems

    Energy Technology Data Exchange (ETDEWEB)

    Halme, A.; Paanajaervi, J. (eds.)

    2004-07-01

    Introduction Biological systems form a versatile and complex entirety on our planet. One evolutionary branch of primates, called humans, has created an extraordinary skill, called technology, by the aid of which it nowadays dominate life on the planet. Humans use technology for producing and harvesting food, healthcare and reproduction, increasing their capability to commute and communicate, defending their territory etc., and to develop more technology. As a result of this, humans have become much technology dependent, so that they have been forced to form a specialized class of humans, called engineers, who take care of the knowledge of technology developing it further and transferring it to later generations. Until now, technology has been relatively independent from biology, although some of its branches, e.g. biotechnology and biomedical engineering, have traditionally been in close contact with it. There exist, however, an increasing interest to expand the interface between technology and biology either by directly utilizing biological processes or materials by combining them with 'dead' technology, or by mimicking in technological solutions the biological innovations created by evolution. The latter theme is in focus of this report, which has been written as the proceeding of the post-graduate seminar 'Bionic Machines and Systems' held at HUT Automation Technology Laboratory in autumn 2003. The underlaying idea of the seminar was to analyze biological species by considering them as 'robotic machines' having various functional subsystems, such as for energy, motion and motion control, perception, navigation, mapping and localization. We were also interested about intelligent capabilities, such as learning and communication, and social structures like swarming behavior and its mechanisms. The word 'bionic machine' comes from the book which was among the initial material when starting our mission to the fascinating world

  9. A survey on queues in machining system: Progress from 2010 to 2017

    Directory of Open Access Journals (Sweden)

    Shekhar C.

    2017-01-01

    Full Text Available The aim of the present article is to give a historical survey of some important research works related to queues in machining system since 2010. Queues of failed machines in machine repairing problem occur due to the failure of machines at random in the manufacturing industries, where different jobs are performed on machining stations. Machines are subject to failure what may result in significant loss of production, revenue, or goodwill. In addition to the references on queues in machining system, which is also called `Machine Repair Problem' (MRP or `Machine Interference Problem' (MIP, a meticulous list of books and survey papers is also prepared so as to provide a detailed catalog for understanding the research in queueing domain. We have classified the relevant literature according to a year of publishing, methodological, and modeling aspects. The author(s hope that this survey paper could be of help to learners contemplating research on queueing domain.

  10. Design of man-machine-communication-systems

    International Nuclear Information System (INIS)

    Zimmermann, R.

    1975-04-01

    This paper shows some fundamentals of man-machine-communication and deduces demands and recommendations for the design of communication systems. The main points are the directives for the design of optic display systems with details for visual perception and resolution, luminance and contrast, as well as discernibility and coding of displayed information. The most important rules are recommendations for acoustic information systems, control devices and for design of consoles are also given. (orig.) [de

  11. Robot path planning using expert systems and machine vision

    Science.gov (United States)

    Malone, Denis E.; Friedrich, Werner E.

    1992-02-01

    This paper describes a system developed for the robotic processing of naturally variable products. In order to plan the robot motion path it was necessary to use a sensor system, in this case a machine vision system, to observe the variations occurring in workpieces and interpret this with a knowledge based expert system. The knowledge base was acquired by carrying out an in-depth study of the product using examination procedures not available in the robotic workplace and relates the nature of the required path to the information obtainable from the machine vision system. The practical application of this system to the processing of fish fillets is described and used to illustrate the techniques.

  12. Cognitive Technologies: The Design of Joint Human-Machine Cognitive Systems

    OpenAIRE

    Woods, David D.

    1985-01-01

    This article explores the implications of one type of cognitive technology, techniques and concepts to develop joint human-machine cognitive systems, for the application of computational technology by examining the joint cognitive system implicit in a hypothetical computer consultant that outputs some form of problem solution. This analysis reveals some of the problems can occur in cognitive system design-e.g., machine control of the interaction, the danger of a responsibility-authority doubl...

  13. The APS machine protection system (MPS)

    Energy Technology Data Exchange (ETDEWEB)

    Fuja, R.; Berg, B.; Arnold, N. [and others

    1996-08-01

    The machine protection system (MPS) that protects the APS storage ring vacuum chamber from x-ray beams, is active. There are over 650 sensors monitored and networked through the MPS system. About the same number of other process variables are monitored by the much slower EPICS control system, which also has an input to the rf abort chain. The MPS network is still growing with the beam position limits detection system coming on-line. The network configuration, along with a limited description of individual subsystems, is presented.

  14. The APS machine protection system (MPS)

    International Nuclear Information System (INIS)

    Fuja, R.; Berg, B.; Arnold, N.

    1996-01-01

    The machine protection system (MPS) that protects the APS storage ring vacuum chamber from x-ray beams, is active. There are over 650 sensors monitored and networked through the MPS system. About the same number of other process variables are monitored by the much slower EPICS control system, which also has an input to the rf abort chain. The MPS network is still growing with the beam position limits detection system coming on-line. The network configuration, along with a limited description of individual subsystems, is presented

  15. Nuclear reactor machine refuelling system

    International Nuclear Information System (INIS)

    Cashen, W.S.; Erwin, D.

    1977-01-01

    Part of an on-line fuelling machine for a CANDU pressure-tube reactor is described. The present invention provides a refuelling machine wherein the fuelling components, including the fuel carrier and the closure adapter, are positively positioned and retained within the machine magazine or positively secured to the machine charge tube head, and cannot be accidentally disengaged as in former practice. The positive positioning devices include an arcuate keeper plate. Simplified hooked fingers are used. (NDH)

  16. State Machine Modeling of the Space Launch System Solid Rocket Boosters

    Science.gov (United States)

    Harris, Joshua A.; Patterson-Hine, Ann

    2013-01-01

    The Space Launch System is a Shuttle-derived heavy-lift vehicle currently in development to serve as NASA's premiere launch vehicle for space exploration. The Space Launch System is a multistage rocket with two Solid Rocket Boosters and multiple payloads, including the Multi-Purpose Crew Vehicle. Planned Space Launch System destinations include near-Earth asteroids, the Moon, Mars, and Lagrange points. The Space Launch System is a complex system with many subsystems, requiring considerable systems engineering and integration. To this end, state machine analysis offers a method to support engineering and operational e orts, identify and avert undesirable or potentially hazardous system states, and evaluate system requirements. Finite State Machines model a system as a finite number of states, with transitions between states controlled by state-based and event-based logic. State machines are a useful tool for understanding complex system behaviors and evaluating "what-if" scenarios. This work contributes to a state machine model of the Space Launch System developed at NASA Ames Research Center. The Space Launch System Solid Rocket Booster avionics and ignition subsystems are modeled using MATLAB/Stateflow software. This model is integrated into a larger model of Space Launch System avionics used for verification and validation of Space Launch System operating procedures and design requirements. This includes testing both nominal and o -nominal system states and command sequences.

  17. 76 FR 63238 - Proximity Detection Systems for Continuous Mining Machines in Underground Coal Mines

    Science.gov (United States)

    2011-10-12

    ... Detection Systems for Continuous Mining Machines in Underground Coal Mines AGENCY: Mine Safety and Health... Agency's proposed rule addressing Proximity Detection Systems for Continuous Mining Machines in... proposed rule for Proximity Detection Systems on Continuous Mining Machines in Underground Coal Mines. Due...

  18. 76 FR 70075 - Proximity Detection Systems for Continuous Mining Machines in Underground Coal Mines

    Science.gov (United States)

    2011-11-10

    ... Detection Systems for Continuous Mining Machines in Underground Coal Mines AGENCY: Mine Safety and Health... proposed rule addressing Proximity Detection Systems for Continuous Mining Machines in Underground Coal... Detection Systems for Continuous Mining Machines in Underground Coal Mines. MSHA conducted hearings on...

  19. Preliminary Development of Real Time Usage-Phase Monitoring System for CNC Machine Tools with a Case Study on CNC Machine VMC 250

    Science.gov (United States)

    Budi Harja, Herman; Prakosa, Tri; Raharno, Sri; Yuwana Martawirya, Yatna; Nurhadi, Indra; Setyo Nogroho, Alamsyah

    2018-03-01

    The production characteristic of job-shop industry at which products have wide variety but small amounts causes every machine tool will be shared to conduct production process with dynamic load. Its dynamic condition operation directly affects machine tools component reliability. Hence, determination of maintenance schedule for every component should be calculated based on actual usage of machine tools component. This paper describes study on development of monitoring system to obtaining information about each CNC machine tool component usage in real time approached by component grouping based on its operation phase. A special device has been developed for monitoring machine tool component usage by utilizing usage phase activity data taken from certain electronics components within CNC machine. The components are adaptor, servo driver and spindle driver, as well as some additional components such as microcontroller and relays. The obtained data are utilized for detecting machine utilization phases such as power on state, machine ready state or spindle running state. Experimental result have shown that the developed CNC machine tool monitoring system is capable of obtaining phase information of machine tool usage as well as its duration and displays the information at the user interface application.

  20. Equivalent model of a dually-fed machine for electric drive control systems

    Science.gov (United States)

    Ostrovlyanchik, I. Yu; Popolzin, I. Yu

    2018-05-01

    The article shows that the mathematical model of a dually-fed machine is complicated because of the presence of a controlled voltage source in the rotor circuit. As a method of obtaining a mathematical model, the method of a generalized two-phase electric machine is applied and a rotating orthogonal coordinate system is chosen that is associated with the representing vector of a stator current. In the chosen coordinate system in the operator form the differential equations of electric equilibrium for the windings of the generalized machine (the Kirchhoff equation) are written together with the expression for the moment, which determines the electromechanical energy transformation in the machine. Equations are transformed so that they connect the currents of the windings, that determine the moment of the machine, and the voltages on these windings. The structural diagram of the machine is assigned to the written equations. Based on the written equations and accepted assumptions, expressions were obtained for the balancing the EMF of windings, and on the basis of these expressions an equivalent mathematical model of a dually-fed machine is proposed, convenient for use in electric drive control systems.

  1. Dynamic processes in technological systems of machining and the nature of their origin

    Science.gov (United States)

    Ershov, D. Y.; Zlotnikov, E. G.; Koboyankwe, L. E.

    2017-10-01

    The article describes the main causes of dynamic processes in technological systems, the types of vibrations that occur in machines, external sources that cause fluctuations in the machine bases. The article discusses the occurrence of self-oscillations in the machines. The authors proposed a mathematical model of a multi-mass technological system based on the example of a vertical drilling machine. The original multi-mass oscillatory system is replaced by a simplified three-mass model, which allows considering the low-frequency range of workloads and disturbing external influences.

  2. Review of the Tandem Mirror Experiment-Upgrade (TMX-U) machine-parameter-instrumentation system

    International Nuclear Information System (INIS)

    Kane, R.J.; Coffield, F.E.; Coutts, G.W.; Hornady, R.S.

    1983-01-01

    The Tandem Mirror Experiment-Upgrade (TMX-U) machine consists of seven major machine subsystems: magnet system, neutral beam system, microwave heating (ECRH), ion heating (ICRH), gas fueling, stream guns, and vacuum system. Satisfactory performance of these subsystems is necessary to achieve the experimental objectives planned for TMX-U operations. Since the performance quality of the subsystem is important and can greatly affect plasma parameters, a 233-channel instrumentation system has been installed. Data from the instrumentation system are acquired and stored with the plasma diagnostic information. Thus, the details of the machine performance are available during post-shot analysis. This paper describes all the machine-parameter-instrumentation hardware, presents some typical data, and outlines how the data are used

  3. A Machine Vision System for Automatically Grading Hardwood Lumber - (Industrial Metrology)

    Science.gov (United States)

    Richard W. Conners; Tai-Hoon Cho; Chong T. Ng; Thomas T. Drayer; Philip A. Araman; Robert L. Brisbon

    1992-01-01

    Any automatic system for grading hardwood lumber can conceptually be divided into two components. One of these is a machine vision system for locating and identifying grading defects. The other is an automatic grading program that accepts as input the output of the machine vision system and, based on these data, determines the grade of a board. The progress that has...

  4. Machine Learning Method Applied in Readout System of Superheated Droplet Detector

    Science.gov (United States)

    Liu, Yi; Sullivan, Clair Julia; d'Errico, Francesco

    2017-07-01

    Direct readability is one advantage of superheated droplet detectors in neutron dosimetry. Utilizing such a distinct characteristic, an imaging readout system analyzes image of the detector for neutron dose readout. To improve the accuracy and precision of algorithms in the imaging readout system, machine learning algorithms were developed. Deep learning neural network and support vector machine algorithms are applied and compared with generally used Hough transform and curvature analysis methods. The machine learning methods showed a much higher accuracy and better precision in recognizing circular gas bubbles.

  5. Homopolar machine for reversible energy storage and transfer systems

    International Nuclear Information System (INIS)

    Stillwagon, R.E.

    1978-01-01

    A homopolar machine designed to operate as a generator and motor in reversibly storing and transferring energy between the machine and a magnetic load coil for a thermonuclear reactor is described. The machine rotor comprises hollow thin-walled cylinders or sleeves which form the basis of the system by utilizing substantially all of the rotor mass as a conductor thus making it possible to transfer substantially all the rotor kinetic energy electrically to the load coil in a highly economical and efficient manner. The rotor is divided into multiple separate cylinders or sleeves of modular design, connected in series and arranged to rotate in opposite directions but maintain the supply of current in a single direction to the machine terminals

  6. TensorFlow: Large-Scale Machine Learning on Heterogeneous Distributed Systems

    OpenAIRE

    Abadi, Martín; Agarwal, Ashish; Barham, Paul; Brevdo, Eugene; Chen, Zhifeng; Citro, Craig; Corrado, Greg S.; Davis, Andy; Dean, Jeffrey; Devin, Matthieu; Ghemawat, Sanjay; Goodfellow, Ian; Harp, Andrew; Irving, Geoffrey; Isard, Michael

    2016-01-01

    TensorFlow is an interface for expressing machine learning algorithms, and an implementation for executing such algorithms. A computation expressed using TensorFlow can be executed with little or no change on a wide variety of heterogeneous systems, ranging from mobile devices such as phones and tablets up to large-scale distributed systems of hundreds of machines and thousands of computational devices such as GPU cards. The system is flexible and can be used to express a wide variety of algo...

  7. The Design of EMG Measurement System for Arm Strength Training Machine

    Directory of Open Access Journals (Sweden)

    Tze-Yee Ho

    2015-01-01

    Full Text Available The setup of interactive communication between arm strength training machine and the people will make exercise and rehabilitation therapy become more friendly. The employment of electromyographic not only can help physical therapy but also can achieve more effective rehabilitation. Both of the system hardware and software of the arm strength training machine with EMG system are well designed and described. The fundamental design of electromyographic measurement system based on a microcontroller is analyzed and discussed. The software programming is developed in MPLAB integrated development environment from the Microchip Technology Inc. and the friendly user interface is created as well. Finally, an arm strength training machine with electromyographic control system is realized and demonstrated. The experimental results show the feasibility and fidelity of the complete designed system.

  8. Optimization of paper machine heat recovery system; Paperikoneen laemmoentalteenottosysteemin optimointi - PMSY 02

    Energy Technology Data Exchange (ETDEWEB)

    Pettersson, H. [Valmet Oyj Pansio, Turku (Finland)

    1998-12-31

    Conventionally the energy content of paper and board machine dryer section exhaust air is recovered in the heat recovery tower. This has had a major contribution to the overall energy economy of a paper machine. Modern paper machines have already reached momentary record speeds above 1700 m/min, and speeds above 2000 m/min will be strived to. This is possible by developing new efficient drying technologies. These will require new solutions for the heat recovery systems. At the same time requirements for new heat recovery solutions come from the gradually closing of paper mill water circulation systems. In this project a discrete tool based on optimization is developed, a tool for analyzing, optimizing and dimensioning of paper machine heat recovery systems for different process conditions. Delivery of a paper machine process requires more and more transferring of process knowledge into calculation model parameters. The overall target of the tool is to decrease the energy consumption considering new drying technologies and the gradually closing of water circulation systems. (orig.)

  9. Optimization of paper machine heat recovery system; Paperikoneen laemmoentalteenottosysteemin optimointi - PMSY 02

    Energy Technology Data Exchange (ETDEWEB)

    Pettersson, H [Valmet Oyj Pansio, Turku (Finland)

    1999-12-31

    Conventionally the energy content of paper and board machine dryer section exhaust air is recovered in the heat recovery tower. This has had a major contribution to the overall energy economy of a paper machine. Modern paper machines have already reached momentary record speeds above 1700 m/min, and speeds above 2000 m/min will be strived to. This is possible by developing new efficient drying technologies. These will require new solutions for the heat recovery systems. At the same time requirements for new heat recovery solutions come from the gradually closing of paper mill water circulation systems. In this project a discrete tool based on optimization is developed, a tool for analyzing, optimizing and dimensioning of paper machine heat recovery systems for different process conditions. Delivery of a paper machine process requires more and more transferring of process knowledge into calculation model parameters. The overall target of the tool is to decrease the energy consumption considering new drying technologies and the gradually closing of water circulation systems. (orig.)

  10. The evolution and practical application of machine translation system (1)

    Science.gov (United States)

    Tominaga, Isao; Sato, Masayuki

    This paper describes a development, practical applicatioin, problem of a system, evaluation of practical system, and development trend of machine translation. Most recent system contains next four problems. 1) the vagueness of a text, 2) a difference of the definition of the terminology between different language, 3) the preparing of a large-scale translation dictionary, 4) the development of a software for the logical inference. Machine translation system is already used practically in many industry fields. However, many problems are not solved. The implementation of an ideal system will be after 15 years. Also, this paper described seven evaluation items detailedly. This English abstract was made by Mu system.

  11. Delay dynamical systems and applications to nonlinear machine-tool chatter

    International Nuclear Information System (INIS)

    Fofana, M.S.

    2003-01-01

    The stability behaviour of machine chatter that exhibits Hopf and degenerate bifurcations has been examined without the assumption of small delays between successive cuts. Delay dynamical system theory leading to the reduction of the infinite-dimensional character of the governing delay differential equations (DDEs) to a finite-dimensional set of ordinary differential equations have been employed. The essential mathematical arguments for these systems in the context of retarded DDEs are summarized. Then the application of these arguments in the stability study of machine-tool chatter with multiple time delays is presented. Explicit analytical expressions ensuring stable and unstable machining when perturbations are periodic, stochastic and nonlinear have been derived using the integral averaging method and Lyapunov exponents

  12. STUDY OF TRANSIENT AND STATIONARY OPERATION MODES OF SYNCHRONOUS SYSTEM CONSISTING IN TWO MACHINES

    Directory of Open Access Journals (Sweden)

    V. S. Safaryan

    2017-01-01

    Full Text Available The solution of the problem of reliable functioning of an electric power system (EPS in steady-state and transient regimes, prevention of EPS transition into asynchronous regime, maintenance and restoration of stability of post-emergency processes is based on formation and realization of mathematical models of an EPS processes. During the functioning of electric power system in asynchronous regime, besides the main frequencies, the currents and voltages include harmonic components, the frequencies of which are multiple of the difference of main frequencies. At the two-frequency asynchronous regime the electric power system is being made equivalent in a form of a two-machine system, functioning for a generalized load. In the article mathematical models of transient process of a two-machine system in natural form and in d–q coordinate system are presented. The mathematical model of two-machine system is considered in case of two windings of excitement at the rotors. Also, in the article varieties of mathematical models of EPS transient regimes (trivial, simple, complete are presented. Transient process of a synchronous two-machine system is described by the complete model. The quality of transient processes of a synchronous machine depends on the number of rotor excitation windings. When there are two excitation windings on the rotor (dual system of excitation, the mathematical model of electromagnetic transient processes of a synchronous machine is represented in a complex form, i.e. in coordinate system d, q, the current of rotor being represented by a generalized vector. In asynchronous operation of a synchronous two-machine system with two excitation windings on the rotor the current and voltage systems include only harmonics of two frequencies. The mathematical model of synchronous steady-state process of a two-machine system is also provided, and the steady-state regimes with different structures of initial information are considered.

  13. System-ergonomic optimisation of the man-machine system nuclear power plant

    International Nuclear Information System (INIS)

    Fechner, J.B.

    1981-01-01

    The nuclear power plant is described as a man-machine system, the approach of system ergonomics is explained as well as its integration in the process of manufacture and operation, and BMI projects to introduce this approach in a wider scale are reviewed. (orig./GL) [de

  14. ADAPTING HYBRID MACHINE TRANSLATION TECHNIQUES FOR CROSS-LANGUAGE TEXT RETRIEVAL SYSTEM

    Directory of Open Access Journals (Sweden)

    P. ISWARYA

    2017-03-01

    Full Text Available This research work aims in developing Tamil to English Cross - language text retrieval system using hybrid machine translation approach. The hybrid machine translation system is a combination of rule based and statistical based approaches. In an existing word by word translation system there are lot of issues and some of them are ambiguity, Out-of-Vocabulary words, word inflections, and improper sentence structure. To handle these issues, proposed architecture is designed in such a way that, it contains Improved Part-of-Speech tagger, machine learning based morphological analyser, collocation based word sense disambiguation procedure, semantic dictionary, and tense markers with gerund ending rules, and two pass transliteration algorithm. From the experimental results it is clear that the proposed Tamil Query based translation system achieves significantly better translation quality over existing system, and reaches 95.88% of monolingual performance.

  15. Prediction of Banking Systemic Risk Based on Support Vector Machine

    Directory of Open Access Journals (Sweden)

    Shouwei Li

    2013-01-01

    Full Text Available Banking systemic risk is a complex nonlinear phenomenon and has shed light on the importance of safeguarding financial stability by recent financial crisis. According to the complex nonlinear characteristics of banking systemic risk, in this paper we apply support vector machine (SVM to the prediction of banking systemic risk in an attempt to suggest a new model with better explanatory power and stability. We conduct a case study of an SVM-based prediction model for Chinese banking systemic risk and find the experiment results showing that support vector machine is an efficient method in such case.

  16. Precision metabolic engineering: The design of responsive, selective, and controllable metabolic systems.

    Science.gov (United States)

    McNerney, Monica P; Watstein, Daniel M; Styczynski, Mark P

    2015-09-01

    Metabolic engineering is generally focused on static optimization of cells to maximize production of a desired product, though recently dynamic metabolic engineering has explored how metabolic programs can be varied over time to improve titer. However, these are not the only types of applications where metabolic engineering could make a significant impact. Here, we discuss a new conceptual framework, termed "precision metabolic engineering," involving the design and engineering of systems that make different products in response to different signals. Rather than focusing on maximizing titer, these types of applications typically have three hallmarks: sensing signals that determine the desired metabolic target, completely directing metabolic flux in response to those signals, and producing sharp responses at specific signal thresholds. In this review, we will first discuss and provide examples of precision metabolic engineering. We will then discuss each of these hallmarks and identify which existing metabolic engineering methods can be applied to accomplish those tasks, as well as some of their shortcomings. Ultimately, precise control of metabolic systems has the potential to enable a host of new metabolic engineering and synthetic biology applications for any problem where flexibility of response to an external signal could be useful. Copyright © 2015 International Metabolic Engineering Society. Published by Elsevier Inc. All rights reserved.

  17. Reliability Evaluation and Improvement Approach of Chemical Production Man - Machine - Environment System

    Science.gov (United States)

    Miao, Yongchun; Kang, Rongxue; Chen, Xuefeng

    2017-12-01

    In recent years, with the gradual extension of reliability research, the study of production system reliability has become the hot topic in various industries. Man-machine-environment system is a complex system composed of human factors, machinery equipment and environment. The reliability of individual factor must be analyzed in order to gradually transit to the research of three-factor reliability. Meanwhile, the dynamic relationship among man-machine-environment should be considered to establish an effective blurry evaluation mechanism to truly and effectively analyze the reliability of such systems. In this paper, based on the system engineering, fuzzy theory, reliability theory, human error, environmental impact and machinery equipment failure theory, the reliabilities of human factor, machinery equipment and environment of some chemical production system were studied by the method of fuzzy evaluation. At last, the reliability of man-machine-environment system was calculated to obtain the weighted result, which indicated that the reliability value of this chemical production system was 86.29. Through the given evaluation domain it can be seen that the reliability of man-machine-environment integrated system is in a good status, and the effective measures for further improvement were proposed according to the fuzzy calculation results.

  18. Computerized system for measuring cerebral metabolism

    International Nuclear Information System (INIS)

    McGlone, J.S.; Hibbard, L.S.; Hawkins, R.A.; Kasturi, R.

    1987-01-01

    A computerized stereotactic measurement system for evaluating rat brain metabolism was developed to utilize the large amount of data generated by quantitative autoradiography. Conventional methods of measurement only analyze a small percent of these data because these methods are limited by instrument design and the subjectiveness of the investigator. However, a computerized system allows digital images to be analyzed by placing data at their appropriate three-dimensional stereotactic coordinates. The system automatically registers experimental data to a standard three-dimensional image using alignment, scaling, and matching operations. Metabolic activity in different neuronal structures is then measured by generating digital masks and superimposing them on to experimental data. Several experimental data sets were evaluated and it was noticed that the structures measured by the computerized system, had in general, lower metabolic activity than manual measurements had indicated. This was expected because the computerized system measured the structure over its volume while the manual readings were taken from the most active metabolic area of a particular structure

  19. Evolution of metabolic network organization

    Directory of Open Access Journals (Sweden)

    Bonchev Danail

    2010-05-01

    Full Text Available Abstract Background Comparison of metabolic networks across species is a key to understanding how evolutionary pressures shape these networks. By selecting taxa representative of different lineages or lifestyles and using a comprehensive set of descriptors of the structure and complexity of their metabolic networks, one can highlight both qualitative and quantitative differences in the metabolic organization of species subject to distinct evolutionary paths or environmental constraints. Results We used a novel representation of metabolic networks, termed network of interacting pathways or NIP, to focus on the modular, high-level organization of the metabolic capabilities of the cell. Using machine learning techniques we identified the most relevant aspects of cellular organization that change under evolutionary pressures. We considered the transitions from prokarya to eukarya (with a focus on the transitions among the archaea, bacteria and eukarya, from unicellular to multicellular eukarya, from free living to host-associated bacteria, from anaerobic to aerobic, as well as the acquisition of cell motility or growth in an environment of various levels of salinity or temperature. Intuitively, we expect organisms with more complex lifestyles to have more complex and robust metabolic networks. Here we demonstrate for the first time that such organisms are not only characterized by larger, denser networks of metabolic pathways but also have more efficiently organized cross communications, as revealed by subtle changes in network topology. These changes are unevenly distributed among metabolic pathways, with specific categories of pathways being promoted to more central locations as an answer to environmental constraints. Conclusions Combining methods from graph theory and machine learning, we have shown here that evolutionary pressures not only affects gene and protein sequences, but also specific details of the complex wiring of functional modules

  20. A review of warship man-machine-environment system engineering

    Directory of Open Access Journals (Sweden)

    ZHANG Yumei

    2017-03-01

    Full Text Available Warship Man-Machine-Environment System Engineering (MMESE is an integral part of the overall design, and its design principles were proposed according to safety, efficiency, comfort and pleasure. The typical characteristics of MMESE are summarized. The operating environment is extremely terrible on long voyages. High level collaboration is required due to the complex task system and large manpower demand. Owing to the dense computer interface information, the mental cognitive burden on the crew is heavy. The MMESE technology system is divided into four parts:man-machine coordinated, man-environment coordinated, the evaluation of man-machine-environment characteristics and the ergonomic simulation. Based on the MMESE development venation in this paper, the overseas and domestic research statuses are expounded. Interactive optimization can be realized according to the following aspects:researching the basic human characteristics of the crew, applying this to the warship's overall design, and formulating relevant ergonomic standards and norms. Next, Human System Integration (HSI professional engineering was introduced comprehensively into the marines in order to achieve an optimal system. On this basis, we completed the future development trend analysis. All these studies and results have some reference meaning for guiding the integrated optimization of warships as a whole, downsizing the manpower and improving efficiency.

  1. Activities of IAEA related to human interface in man-machine system

    International Nuclear Information System (INIS)

    Nishiwaki, Yasushi

    1988-01-01

    The present paper outlines some activities of IAEA related to human interface in man-machine systems. It has been recognized for quite some time that in large and complex man-machine interactive systems human errors can contribute substantially to failures of these systems, and that the improvement in the human interface in man-machine systems is essential for the safety of the plant. Many important surveys have been made in some member countries. These studies and operational experience have shown that it is possible to substantially reduce this adverse impact of human errors in nuclear power plant operations by the application of human factors technology. This technology. This technology includes: (1) selection of people with the requisite skills and knowledge and providing them with job-relevant training, (2) maintenance of the necessary job qualifications for each person in the plant, (3) design of man-machine interfaces which are fully compatible with the capabilities and limitations of the people in the system, and (4) design of job operations, including written materials, to facilitate required quality of human performance. A review is made of education/training, operator support systems, human error data collection, analysis of safety significant events and future activities. (Nogami, K.)

  2. Hydraulic Modular Dosaging Systems for Machine Drives

    Directory of Open Access Journals (Sweden)

    A. J. Kotlobai

    2005-01-01

    Full Text Available The justified principle of making modular dosaging systems for positive-displacement multimotor hydraulic drives used in running gear and technological equipment of mobile construction, road and agricultural machines makes it possible to synchronize motion of running parts. The examples of the realization of modular dosaging systems and an algorithm of their operation are given in the paper.

  3. Stability Assessment of a System Comprising a Single Machine and Inverter with Scalable Ratings

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, Brian B [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Lin, Yashen [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Gevorgian, Vahan [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Purba, Victor [University of Minnesota; Dhople, Sairaj [University of Minnesota

    2017-09-28

    From the inception of power systems, synchronous machines have acted as the foundation of large-scale electrical infrastructures and their physical properties have formed the cornerstone of system operations. However, power electronics interfaces are playing a growing role as they are the primary interface for several types of renewable energy sources and storage technologies. As the role of power electronics in systems continues to grow, it is crucial to investigate the properties of bulk power systems in low inertia settings. In this paper, we assess the properties of coupled machine-inverter systems by studying an elementary system comprised of a synchronous generator, three-phase inverter, and a load. Furthermore, the inverter model is formulated such that its power rating can be scaled continuously across power levels while preserving its closed-loop response. Accordingly, the properties of the machine-inverter system can be assessed for varying ratios of machine-to-inverter power ratings and, hence, differing levels of inertia. After linearizing the model and assessing its eigenvalues, we show that system stability is highly dependent on the interaction between the inverter current controller and machine exciter, thus uncovering a key concern with mixed machine-inverter systems and motivating the need for next-generation grid-stabilizing inverter controls.

  4. Practical implementation of machine tool metrology and maintenance management systems

    International Nuclear Information System (INIS)

    Perkins, C; Longstaff, A P; Fletcher, S; Willoughby, P

    2012-01-01

    Maximising asset utilisation and minimising downtime and waste are becoming increasingly important to all manufacturing facilities as competition increases and profits decrease. The tools to assist with monitoring these machining processes are becoming more and more in demand. A system designed to fulfil the needs of machine tool operators and supervisors has been developed and its impact on the precision manufacturing industry is being considered. The benefits of implementing this system, compared to traditional methods, will be discussed here.

  5. Considerations for automated machine learning in clinical metabolic profiling: Altered homocysteine plasma concentration associated with metformin exposure.

    Science.gov (United States)

    Orlenko, Alena; Moore, Jason H; Orzechowski, Patryk; Olson, Randal S; Cairns, Junmei; Caraballo, Pedro J; Weinshilboum, Richard M; Wang, Liewei; Breitenstein, Matthew K

    2018-01-01

    With the maturation of metabolomics science and proliferation of biobanks, clinical metabolic profiling is an increasingly opportunistic frontier for advancing translational clinical research. Automated Machine Learning (AutoML) approaches provide exciting opportunity to guide feature selection in agnostic metabolic profiling endeavors, where potentially thousands of independent data points must be evaluated. In previous research, AutoML using high-dimensional data of varying types has been demonstrably robust, outperforming traditional approaches. However, considerations for application in clinical metabolic profiling remain to be evaluated. Particularly, regarding the robustness of AutoML to identify and adjust for common clinical confounders. In this study, we present a focused case study regarding AutoML considerations for using the Tree-Based Optimization Tool (TPOT) in metabolic profiling of exposure to metformin in a biobank cohort. First, we propose a tandem rank-accuracy measure to guide agnostic feature selection and corresponding threshold determination in clinical metabolic profiling endeavors. Second, while AutoML, using default parameters, demonstrated potential to lack sensitivity to low-effect confounding clinical covariates, we demonstrated residual training and adjustment of metabolite features as an easily applicable approach to ensure AutoML adjustment for potential confounding characteristics. Finally, we present increased homocysteine with long-term exposure to metformin as a potentially novel, non-replicated metabolite association suggested by TPOT; an association not identified in parallel clinical metabolic profiling endeavors. While warranting independent replication, our tandem rank-accuracy measure suggests homocysteine to be the metabolite feature with largest effect, and corresponding priority for further translational clinical research. Residual training and adjustment for a potential confounding effect by BMI only slightly modified

  6. A heuristic for the inventory management of smart vending machine systems

    Directory of Open Access Journals (Sweden)

    Yang-Byung Park

    2012-12-01

    Full Text Available Purpose: The purpose of this paper is to propose a heuristic for the inventory management of smart vending machine systems with product substitution under the replenishment point, order-up-to level policy and to evaluate its performance.Design/methodology/approach: The heuristic is developed on the basis of the decoupled approach. An integer linear mathematical model is built to determine the number of product storage compartments and replenishment threshold for each smart vending machine in the system and the Clarke and Wright’s savings algorithm is applied to route vehicles for inventory replenishments of smart vending machines that share the same delivery days. Computational experiments are conducted on several small-size test problems to compare the proposed heuristic with the integrated optimization mathematical model with respect to system profit. Furthermore, a sensitivity analysis is carried out on a medium-size test problem to evaluate the effect of the customer service level on system profit using a computer simulation.Findings: The results show that the proposed heuristic yielded pretty good solutions with 5.7% error rate on average compared to the optimal solutions. The proposed heuristic took about 3 CPU minutes on average in the test problems being consisted of 10 five-product smart vending machines. It was confirmed that the system profit is significantly affected by the customer service level.Originality/value: The inventory management of smart vending machine systems is newly treated. Product substitutions are explicitly considered in the model. The proposed heuristic is effective as well as efficient. It can be easily modified for application to various retail vending settings under a vendor-managed inventory scheme with POS system.

  7. Ecological Design of Cooperative Human-Machine Interfaces for Safety of Intelligent Transport Systems

    Directory of Open Access Journals (Sweden)

    Orekhov Aleksandr

    2016-01-01

    Full Text Available The paper describes research results in the domain of cooperative intelligent transport systems. The requirements for human-machine interface considering safety issue of for intelligent transport systems (ITSare analyzed. Profiling of the requirements to cooperative human-machine interface (CHMI for such systems including requirements to usability and safety is based on a set of standards for ITSs. An approach and design technique of cooperative human-machine interface for ITSs are suggested. The architecture of cloud-based CHMI for intelligent transport systems has been developed. The prototype of software system CHMI4ITSis described.

  8. An analysis of machine translation and speech synthesis in speech-to-speech translation system

    OpenAIRE

    Hashimoto, K.; Yamagishi, J.; Byrne, W.; King, S.; Tokuda, K.

    2011-01-01

    This paper provides an analysis of the impacts of machine translation and speech synthesis on speech-to-speech translation systems. The speech-to-speech translation system consists of three components: speech recognition, machine translation and speech synthesis. Many techniques for integration of speech recognition and machine translation have been proposed. However, speech synthesis has not yet been considered. Therefore, in this paper, we focus on machine translation and speech synthesis, ...

  9. Optimization of AVR Parameters of a Multi-machine Power System ...

    African Journals Online (AJOL)

    user1

    Keywords: multi-machine power system stability, AVR system, power system stabilizer, PID controller ... The proposed controller was a fuzzy-logic-based stabilizer that has the capability to ..... Computer methods in power system analysis.

  10. Modelling machine ensembles with discrete event dynamical system theory

    Science.gov (United States)

    Hunter, Dan

    1990-01-01

    Discrete Event Dynamical System (DEDS) theory can be utilized as a control strategy for future complex machine ensembles that will be required for in-space construction. The control strategy involves orchestrating a set of interactive submachines to perform a set of tasks for a given set of constraints such as minimum time, minimum energy, or maximum machine utilization. Machine ensembles can be hierarchically modeled as a global model that combines the operations of the individual submachines. These submachines are represented in the global model as local models. Local models, from the perspective of DEDS theory , are described by the following: a set of system and transition states, an event alphabet that portrays actions that takes a submachine from one state to another, an initial system state, a partial function that maps the current state and event alphabet to the next state, and the time required for the event to occur. Each submachine in the machine ensemble is presented by a unique local model. The global model combines the local models such that the local models can operate in parallel under the additional logistic and physical constraints due to submachine interactions. The global model is constructed from the states, events, event functions, and timing requirements of the local models. Supervisory control can be implemented in the global model by various methods such as task scheduling (open-loop control) or implementing a feedback DEDS controller (closed-loop control).

  11. Support vector machine in machine condition monitoring and fault diagnosis

    Science.gov (United States)

    Widodo, Achmad; Yang, Bo-Suk

    2007-08-01

    Recently, the issue of machine condition monitoring and fault diagnosis as a part of maintenance system became global due to the potential advantages to be gained from reduced maintenance costs, improved productivity and increased machine availability. This paper presents a survey of machine condition monitoring and fault diagnosis using support vector machine (SVM). It attempts to summarize and review the recent research and developments of SVM in machine condition monitoring and diagnosis. Numerous methods have been developed based on intelligent systems such as artificial neural network, fuzzy expert system, condition-based reasoning, random forest, etc. However, the use of SVM for machine condition monitoring and fault diagnosis is still rare. SVM has excellent performance in generalization so it can produce high accuracy in classification for machine condition monitoring and diagnosis. Until 2006, the use of SVM in machine condition monitoring and fault diagnosis is tending to develop towards expertise orientation and problem-oriented domain. Finally, the ability to continually change and obtain a novel idea for machine condition monitoring and fault diagnosis using SVM will be future works.

  12. Man-machine systems research at the OECD Halden reactor project

    International Nuclear Information System (INIS)

    Owre, F.; Bjorlo, T.J.; Haugset, K.

    1994-01-01

    The OECD Halden Reactor Project is a jointly financed research programme under the auspices of the OECD - Nuclear Energy Agency with fifteen participating countries. One of the main research topics focuses on man-machine systems. Particular attention is paid to the operator's tasks in the reactor control room environment. The overall objective of the research in this field is to provide a basis for improving today's control rooms through the introduction of computer-based solutions for the effective and safe execution of surveillance and control functions in normal as well as off-normal plant situations. The programme comprises four main activities: the verification and validation of safety critical software systems; man-machine interaction research emphasizing improvements in man-machine interfaces on the basis of human factors studies; computerised operator support systems assisting the operator in fault detection/diagnosis and planning of control actions; and control room development providing a basis for retrofitting of existing control rooms and for the design of advanced concepts

  13. MITI project on advanced man-machine system for nuclear power plants

    International Nuclear Information System (INIS)

    Kato, Kanji; Watanabe, Takao; Hayakawa, Hiroyasu; Naito, Norio; Masui, Takao; Ogino, Takamichi.

    1988-01-01

    A computerized operator support system (COSS) against abnormal plant conditions was developed as a five-year project from 1980 to 1984, under the sponsorship of the Ministry of International Trade and Industry. The main purpose of the COSS development was to implement the lessons learned from the Three Mile Island accident. The main nuclear industries in Japan participated in the project. The design concept of the operator support functions and the method to implement it were established, and the prototype systems of the COSS for BWR and PWR plants were developed. After the completion of the COSS development, the above participant group once again joined for the work on an advanced man-machine system for nuclear power plants (MMS-NPP). This eight-year project aims at realizing an advanced operator support system by applying artificial intelligence, especially knowledge engineering, and sophisticated man-machine interface devices. Its main objectives are shown. This system configuration, operating method decision system, man-machine communication system, operation and maintenance support functions and so on are described. (Kako, I.)

  14. Which Management Control System principles and aspects are relevant when deploying a learning machine?

    OpenAIRE

    Martin, Johansson; Mikael, Göthager

    2017-01-01

    How shall a business adapt its management control systems when learning machines enter the arena? Will the control system continue to focus on humans aspects and continue to consider a learning machine to be an automation tool as any other historically programmed computer? Learning machines introduces productivity capabilities that achieve very high levels of efficiency and quality. A learning machine can sort through large amounts of data and make conclusions difficult by a human mind. Howev...

  15. DNA-based machines.

    Science.gov (United States)

    Wang, Fuan; Willner, Bilha; Willner, Itamar

    2014-01-01

    The base sequence in nucleic acids encodes substantial structural and functional information into the biopolymer. This encoded information provides the basis for the tailoring and assembly of DNA machines. A DNA machine is defined as a molecular device that exhibits the following fundamental features. (1) It performs a fuel-driven mechanical process that mimics macroscopic machines. (2) The mechanical process requires an energy input, "fuel." (3) The mechanical operation is accompanied by an energy consumption process that leads to "waste products." (4) The cyclic operation of the DNA devices, involves the use of "fuel" and "anti-fuel" ingredients. A variety of DNA-based machines are described, including the construction of "tweezers," "walkers," "robots," "cranes," "transporters," "springs," "gears," and interlocked cyclic DNA structures acting as reconfigurable catenanes, rotaxanes, and rotors. Different "fuels", such as nucleic acid strands, pH (H⁺/OH⁻), metal ions, and light, are used to trigger the mechanical functions of the DNA devices. The operation of the devices in solution and on surfaces is described, and a variety of optical, electrical, and photoelectrochemical methods to follow the operations of the DNA machines are presented. We further address the possible applications of DNA machines and the future perspectives of molecular DNA devices. These include the application of DNA machines as functional structures for the construction of logic gates and computing, for the programmed organization of metallic nanoparticle structures and the control of plasmonic properties, and for controlling chemical transformations by DNA machines. We further discuss the future applications of DNA machines for intracellular sensing, controlling intracellular metabolic pathways, and the use of the functional nanostructures for drug delivery and medical applications.

  16. ANN Based Tool Condition Monitoring System for CNC Milling Machines

    Directory of Open Access Journals (Sweden)

    Mota-Valtierra G.C.

    2011-10-01

    Full Text Available Most of the companies have as objective to manufacture high-quality products, then by optimizing costs, reducing and controlling the variations in its production processes it is possible. Within manufacturing industries a very important issue is the tool condition monitoring, since the tool state will determine the quality of products. Besides, a good monitoring system will protect the machinery from severe damages. For determining the state of the cutting tools in a milling machine, there is a great variety of models in the industrial market, however these systems are not available to all companies because of their high costs and the requirements of modifying the machining tool in order to attach the system sensors. This paper presents an intelligent classification system which determines the status of cutt ers in a Computer Numerical Control (CNC milling machine. This tool state is mainly detected through the analysis of the cutting forces drawn from the spindle motors currents. This monitoring system does not need sensors so it is no necessary to modify the machine. The correct classification is made by advanced digital signal processing techniques. Just after acquiring a signal, a FIR digital filter is applied to the data to eliminate the undesired noisy components and to extract the embedded force components. A Wavelet Transformation is applied to the filtered signal in order to compress the data amount and to optimize the classifier structure. Then a multilayer perceptron- type neural network is responsible for carrying out the classification of the signal. Achieving a reliability of 95%, the system is capable of detecting breakage and a worn cutter.

  17. Machine learning strategies for systems with invariance properties

    Science.gov (United States)

    Ling, Julia; Jones, Reese; Templeton, Jeremy

    2016-08-01

    In many scientific fields, empirical models are employed to facilitate computational simulations of engineering systems. For example, in fluid mechanics, empirical Reynolds stress closures enable computationally-efficient Reynolds Averaged Navier Stokes simulations. Likewise, in solid mechanics, constitutive relations between the stress and strain in a material are required in deformation analysis. Traditional methods for developing and tuning empirical models usually combine physical intuition with simple regression techniques on limited data sets. The rise of high performance computing has led to a growing availability of high fidelity simulation data. These data open up the possibility of using machine learning algorithms, such as random forests or neural networks, to develop more accurate and general empirical models. A key question when using data-driven algorithms to develop these empirical models is how domain knowledge should be incorporated into the machine learning process. This paper will specifically address physical systems that possess symmetry or invariance properties. Two different methods for teaching a machine learning model an invariance property are compared. In the first method, a basis of invariant inputs is constructed, and the machine learning model is trained upon this basis, thereby embedding the invariance into the model. In the second method, the algorithm is trained on multiple transformations of the raw input data until the model learns invariance to that transformation. Results are discussed for two case studies: one in turbulence modeling and one in crystal elasticity. It is shown that in both cases embedding the invariance property into the input features yields higher performance at significantly reduced computational training costs.

  18. Rapid Prediction of Bacterial Heterotrophic Fluxomics Using Machine Learning and Constraint Programming.

    Directory of Open Access Journals (Sweden)

    Stephen Gang Wu

    2016-04-01

    Full Text Available 13C metabolic flux analysis (13C-MFA has been widely used to measure in vivo enzyme reaction rates (i.e., metabolic flux in microorganisms. Mining the relationship between environmental and genetic factors and metabolic fluxes hidden in existing fluxomic data will lead to predictive models that can significantly accelerate flux quantification. In this paper, we present a web-based platform MFlux (http://mflux.org that predicts the bacterial central metabolism via machine learning, leveraging data from approximately 100 13C-MFA papers on heterotrophic bacterial metabolisms. Three machine learning methods, namely Support Vector Machine (SVM, k-Nearest Neighbors (k-NN, and Decision Tree, were employed to study the sophisticated relationship between influential factors and metabolic fluxes. We performed a grid search of the best parameter set for each algorithm and verified their performance through 10-fold cross validations. SVM yields the highest accuracy among all three algorithms. Further, we employed quadratic programming to adjust flux profiles to satisfy stoichiometric constraints. Multiple case studies have shown that MFlux can reasonably predict fluxomes as a function of bacterial species, substrate types, growth rate, oxygen conditions, and cultivation methods. Due to the interest of studying model organism under particular carbon sources, bias of fluxome in the dataset may limit the applicability of machine learning models. This problem can be resolved after more papers on 13C-MFA are published for non-model species.

  19. Improving Machining Accuracy of CNC Machines with Innovative Design Methods

    Science.gov (United States)

    Yemelyanov, N. V.; Yemelyanova, I. V.; Zubenko, V. L.

    2018-03-01

    The article considers achieving the machining accuracy of CNC machines by applying innovative methods in modelling and design of machining systems, drives and machine processes. The topological method of analysis involves visualizing the system as matrices of block graphs with a varying degree of detail between the upper and lower hierarchy levels. This approach combines the advantages of graph theory and the efficiency of decomposition methods, it also has visual clarity, which is inherent in both topological models and structural matrices, as well as the resiliency of linear algebra as part of the matrix-based research. The focus of the study is on the design of automated machine workstations, systems, machines and units, which can be broken into interrelated parts and presented as algebraic, topological and set-theoretical models. Every model can be transformed into a model of another type, and, as a result, can be interpreted as a system of linear and non-linear equations which solutions determine the system parameters. This paper analyses the dynamic parameters of the 1716PF4 machine at the stages of design and exploitation. Having researched the impact of the system dynamics on the component quality, the authors have developed a range of practical recommendations which have enabled one to reduce considerably the amplitude of relative motion, exclude some resonance zones within the spindle speed range of 0...6000 min-1 and improve machining accuracy.

  20. Homopolar machine for reversible energy storage and transfer systems

    Science.gov (United States)

    Stillwagon, Roy E.

    1978-01-01

    A homopolar machine designed to operate as a generator and motor in reversibly storing and transferring energy between the machine and a magnetic load coil for a thermo-nuclear reactor. The machine rotor comprises hollow thin-walled cylinders or sleeves which form the basis of the system by utilizing substantially all of the rotor mass as a conductor thus making it possible to transfer substantially all the rotor kinetic energy electrically to the load coil in a highly economical and efficient manner. The rotor is divided into multiple separate cylinders or sleeves of modular design, connected in series and arranged to rotate in opposite directions but maintain the supply of current in a single direction to the machine terminals. A stator concentrically disposed around the sleeves consists of a hollow cylinder having a number of excitation coils each located radially outward from the ends of adjacent sleeves. Current collected at an end of each sleeve by sleeve slip rings and brushes is transferred through terminals to the magnetic load coil. Thereafter, electrical energy returned from the coil then flows through the machine which causes the sleeves to motor up to the desired speed in preparation for repetition of the cycle. To eliminate drag on the rotor between current pulses, the brush rigging is designed to lift brushes from all slip rings in the machine.

  1. Homopolar machine for reversible energy storage and transfer systems

    International Nuclear Information System (INIS)

    Stillwagon, R.E.

    1981-01-01

    A homopolar machine designed to operate as a generator and motor in reversibly storing and transferring energy between the machine and a magnetic load coil for a thermo-nuclear reactor. The machine rotor comprises hollow thin-walled cylinders or sleeves which form the basis of the system by utilizing substantially all of the rotor mass as a conductor thus making it possible to transfer substantially all the rotor kinetic energy electrically to the load coil in a highly economical and efficient manner. The rotor is divided into multiple separate cylinders or sleeves of modular design, connected in series and arranged to rotate in opposite directions but maintain the supply of current in a single direction to the machine terminals. A stator concentrically disposed around the sleeves consists of a hollow cylinder having a number of excitation coils each located radially outward from the ends of adjacent sleeves. Current collected at an end of each sleeve by sleeve slip rings and brushes is transferred through terminals to the magnetic load coil. Thereafter, electrical energy returned from the coil then flows through the machine which causes the sleeves to motor up to the desired speed in preparation for repetition of the cycle. To eliminate drag on the rotor between current pulses, the brush rigging is designed to lift brushes from all slip rings in the machine

  2. Code-expanded radio access protocol for machine-to-machine communications

    DEFF Research Database (Denmark)

    Thomsen, Henning; Kiilerich Pratas, Nuno; Stefanovic, Cedomir

    2013-01-01

    The random access methods used for support of machine-to-machine, also referred to as Machine-Type Communications, in current cellular standards are derivatives of traditional framed slotted ALOHA and therefore do not support high user loads efficiently. We propose an approach that is motivated b...... subframes and orthogonal preambles, the amount of available contention resources is drastically increased, enabling the massive support of Machine-Type Communication users that is beyond the reach of current systems.......The random access methods used for support of machine-to-machine, also referred to as Machine-Type Communications, in current cellular standards are derivatives of traditional framed slotted ALOHA and therefore do not support high user loads efficiently. We propose an approach that is motivated...... by the random access method employed in LTE, which significantly increases the amount of contention resources without increasing the system resources, such as contention subframes and preambles. This is accomplished by a logical, rather than physical, extension of the access method in which the available system...

  3. Machine Translation as a complex system, and the phenomenon of Esperanto

    NARCIS (Netherlands)

    Gobbo, F.

    2015-01-01

    The history of machine translation and the history of Esperanto have long been connected, as they are two different ways to deal with the same problem: the problem of communication across language barriers. Language can be considered a Complex Adaptive System (CAS), and machine translation too. In

  4. An Automatic Assembling System for Sealing Rings Based on Machine Vision

    Directory of Open Access Journals (Sweden)

    Mingyu Gao

    2017-01-01

    Full Text Available In order to grab and place the sealing rings of battery lid quickly and accurately, an automatic assembling system for sealing rings based on machine vision is developed in this paper. The whole system is composed of the light sources, cameras, industrial control units, and a 4-degree-of-freedom industrial robot. Specifically, the sealing rings are recognized and located automatically with the machine vision module. Then industrial robot is controlled for grabbing the sealing rings dynamically under the joint work of multiple control units and visual feedback. Furthermore, the coordinates of the fast-moving battery lid are tracked by the machine vision module. Finally the sealing rings are placed on the sealing ports of battery lid accurately and automatically. Experimental results demonstrate that the proposed system can grab the sealing rings and place them on the sealing port of the fast-moving battery lid successfully. More importantly, the proposed system can improve the efficiency of the battery production line obviously.

  5. An Android malware detection system based on machine learning

    Science.gov (United States)

    Wen, Long; Yu, Haiyang

    2017-08-01

    The Android smartphone, with its open source character and excellent performance, has attracted many users. However, the convenience of the Android platform also has motivated the development of malware. The traditional method which detects the malware based on the signature is unable to detect unknown applications. The article proposes a machine learning-based lightweight system that is capable of identifying malware on Android devices. In this system we extract features based on the static analysis and the dynamitic analysis, then a new feature selection approach based on principle component analysis (PCA) and relief are presented in the article to decrease the dimensions of the features. After that, a model will be constructed with support vector machine (SVM) for classification. Experimental results show that our system provides an effective method in Android malware detection.

  6. Concept of a Machine Protection System for the High-Energy LHC

    CERN Document Server

    Raginel, Vivien; Wollmann, Daniel

    2018-01-01

    The High-Energy LHC (HE-LHC) is setting new precedents in stored energy in both, the superconducting magnet system (∼ 20 GJ) and the beams (1.34 GJ) as compared to LHC and the LHC upgrade to increase the luminosity (HL-LHC). Therefore, the requirements and performance of the existing machine protection systems have to be reviewed and adapted to the new HE-LHC beam parameters, failure cases and machine availability requirements.

  7. Evaluation of man-machine systems - methods and problems

    International Nuclear Information System (INIS)

    1985-01-01

    The symposium gives a survey of the methods of evaluation which permit as quantitive an assessment as possible of the collaboration between men and machines. This complex of problems is of great current significance in many areas of application. The systems to be evaluated are aircraft, land vehicles and watercraft as well as process control systems. (orig./GL) [de

  8. 76 FR 54163 - Proximity Detection Systems for Continuous Mining Machines in Underground Coal Mines

    Science.gov (United States)

    2011-08-31

    ... Detection Systems for Continuous Mining Machines in Underground Coal Mines AGENCY: Mine Safety and Health... (except full-face continuous mining machines) with proximity detection systems. Miners working near..., each underground coal mine operator would be required to install proximity detection systems on...

  9. Hybrid machining processes perspectives on machining and finishing

    CERN Document Server

    Gupta, Kapil; Laubscher, R F

    2016-01-01

    This book describes various hybrid machining and finishing processes. It gives a critical review of the past work based on them as well as the current trends and research directions. For each hybrid machining process presented, the authors list the method of material removal, machining system, process variables and applications. This book provides a deep understanding of the need, application and mechanism of hybrid machining processes.

  10. 21 CFR 862.3360 - Drug metabolizing enzyme genotyping system.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Drug metabolizing enzyme genotyping system. 862... Test Systems § 862.3360 Drug metabolizing enzyme genotyping system. (a) Identification. A drug metabolizing enzyme genotyping system is a device intended for use in testing deoxyribonucleic acid (DNA...

  11. Design of electric control system for automatic vegetable bundling machine

    Science.gov (United States)

    Bao, Yan

    2017-06-01

    A design can meet the requirements of automatic bale food structure and has the advantages of simple circuit, and the volume is easy to enhance the electric control system of machine carrying bunch of dishes and low cost. The bundle of vegetable machine should meet the sensor to detect and control, in order to meet the control requirements; binding force can be adjusted by the button to achieve; strapping speed also can be adjusted, by the keys to set; sensors and mechanical line connection, convenient operation; can be directly connected with the plug, the 220V power supply can be connected to a power source; if, can work, by the transmission signal sensor, MCU to control the motor, drive and control procedures for small motor. The working principle of LED control circuit and temperature control circuit is described. The design of electric control system of automatic dish machine.

  12. The Abstract Machine Model for Transaction-based System Control

    Energy Technology Data Exchange (ETDEWEB)

    Chassin, David P.

    2003-01-31

    Recent work applying statistical mechanics to economic modeling has demonstrated the effectiveness of using thermodynamic theory to address the complexities of large scale economic systems. Transaction-based control systems depend on the conjecture that when control of thermodynamic systems is based on price-mediated strategies (e.g., auctions, markets), the optimal allocation of resources in a market-based control system results in an emergent optimal control of the thermodynamic system. This paper proposes an abstract machine model as the necessary precursor for demonstrating this conjecture and establishes the dynamic laws as the basis for a special theory of emergence applied to the global behavior and control of complex adaptive systems. The abstract machine in a large system amounts to the analog of a particle in thermodynamic theory. The permit the establishment of a theory dynamic control of complex system behavior based on statistical mechanics. Thus we may be better able to engineer a few simple control laws for a very small number of devices types, which when deployed in very large numbers and operated as a system of many interacting markets yields the stable and optimal control of the thermodynamic system.

  13. Systems Biology as an Integrated Platform for Bioinformatics, Systems Synthetic Biology, and Systems Metabolic Engineering

    Science.gov (United States)

    Chen, Bor-Sen; Wu, Chia-Chou

    2013-01-01

    Systems biology aims at achieving a system-level understanding of living organisms and applying this knowledge to various fields such as synthetic biology, metabolic engineering, and medicine. System-level understanding of living organisms can be derived from insight into: (i) system structure and the mechanism of biological networks such as gene regulation, protein interactions, signaling, and metabolic pathways; (ii) system dynamics of biological networks, which provides an understanding of stability, robustness, and transduction ability through system identification, and through system analysis methods; (iii) system control methods at different levels of biological networks, which provide an understanding of systematic mechanisms to robustly control system states, minimize malfunctions, and provide potential therapeutic targets in disease treatment; (iv) systematic design methods for the modification and construction of biological networks with desired behaviors, which provide system design principles and system simulations for synthetic biology designs and systems metabolic engineering. This review describes current developments in systems biology, systems synthetic biology, and systems metabolic engineering for engineering and biology researchers. We also discuss challenges and future prospects for systems biology and the concept of systems biology as an integrated platform for bioinformatics, systems synthetic biology, and systems metabolic engineering. PMID:24709875

  14. Systems Biology as an Integrated Platform for Bioinformatics, Systems Synthetic Biology, and Systems Metabolic Engineering

    Directory of Open Access Journals (Sweden)

    Bor-Sen Chen

    2013-10-01

    Full Text Available Systems biology aims at achieving a system-level understanding of living organisms and applying this knowledge to various fields such as synthetic biology, metabolic engineering, and medicine. System-level understanding of living organisms can be derived from insight into: (i system structure and the mechanism of biological networks such as gene regulation, protein interactions, signaling, and metabolic pathways; (ii system dynamics of biological networks, which provides an understanding of stability, robustness, and transduction ability through system identification, and through system analysis methods; (iii system control methods at different levels of biological networks, which provide an understanding of systematic mechanisms to robustly control system states, minimize malfunctions, and provide potential therapeutic targets in disease treatment; (iv systematic design methods for the modification and construction of biological networks with desired behaviors, which provide system design principles and system simulations for synthetic biology designs and systems metabolic engineering. This review describes current developments in systems biology, systems synthetic biology, and systems metabolic engineering for engineering and biology researchers. We also discuss challenges and future prospects for systems biology and the concept of systems biology as an integrated platform for bioinformatics, systems synthetic biology, and systems metabolic engineering.

  15. Networks of Zeeman catastrophe machines for the investigation of complex systems

    International Nuclear Information System (INIS)

    Nagy, Péter; Tasnádi, Péter

    2014-01-01

    The investigation of chaotic motion and cooperative systems presents a great opportunity to involve modern physics into the basic course of mechanics taught to BSc-level students. In our previous paper (2014 Eur. J. Phys. 35 015018), it was demonstrated that a Zeeman machine can be a versatile and motivating tool for students to gain introductory knowledge about chaotic motion via interactive simulations. Although the Zeeman machine is known mainly for its quasi-static and catastrophic behaviour, its dynamic properties are also very interesting and show typical chaotic features. In this paper, we present a novel construction consisting of Zeeman machines linked into a network. Although Zeeman networks can be built with almost arbitrary topology, our discussion is restricted to a system where Zeeman machines are arranged in a two-dimensional periodical lattice and the angular variables of the machines are limited to discrete values only. It will be shown that the Zeeman-crystal is appropriate for studying the properties of a broad range of complex systems. Using NetLogo simulations (second- and first-order) phase transitions, its ferromagnetic- and anti-ferromagnetic-type behaviour is demonstrated. A limiting case of the theoretical model of Zeeman-crystal leads to a model that is analogous to the Potts clock model used frequently in statistical physics. The present paper is organically linked to our website (http://csodafizika.hu/zeeman) where downloadable simulations, which are discussed in the paper, can be found. (paper)

  16. Integrated Real-Virtuality System and Environments for Advanced Control System Developers and Machines Builders

    OpenAIRE

    Hussein, Mohamed

    2008-01-01

    The pace of technological change is increasing and sophisticated customer driven markets are forcing rapid machine evolution, increasing complexity and quality, and faster response. To survive and thrive in these markets, machine builders/suppliers require absolute customer and market orientation, focusing on .. rapid provision of solutions rather than products. Their production systems will need to accommodate unpredictable changes while maintaining financial and operational efficiency with ...

  17. MACHINE LEARNING FOR THE SELF-ORGANIZATION OF DISTRIBUTED SYSTEMS IN ECONOMIC APPLICATIONS

    Directory of Open Access Journals (Sweden)

    Jerzy Balicki

    2017-03-01

    Full Text Available In this paper, an application of machine learning to the problem of self-organization of distributed systems has been discussed with regard to economic applications, with particular emphasis on supervised neural network learning to predict stock investments and some ratings of companies. In addition, genetic programming can play an important role in the preparation and testing of several financial information systems. For this reason, machine learning applications have been discussed because some software applications can be automatically constructed by genetic programming. To obtain a competitive advantage, machine learning can be used for the management of self-organizing cloud computing systems performing calculations for business. Also the use of selected economic self-organizing distributed systems has been described, including some testing methods of predicting borrower reliability. Finally, some conclusions and directions for further research have been proposed.

  18. Environmentally Friendly Machining

    CERN Document Server

    Dixit, U S; Davim, J Paulo

    2012-01-01

    Environment-Friendly Machining provides an in-depth overview of environmentally-friendly machining processes, covering numerous different types of machining in order to identify which practice is the most environmentally sustainable. The book discusses three systems at length: machining with minimal cutting fluid, air-cooled machining and dry machining. Also covered is a way to conserve energy during machining processes, along with useful data and detailed descriptions for developing and utilizing the most efficient modern machining tools. Researchers and engineers looking for sustainable machining solutions will find Environment-Friendly Machining to be a useful volume.

  19. Metabolic routes along digestive system of licorice: multicomponent sequential metabolism method in rat.

    Science.gov (United States)

    Zhang, Lei; Zhao, Haiyu; Liu, Yang; Dong, Honghuan; Lv, Beiran; Fang, Min; Zhao, Huihui

    2016-06-01

    This study was conducted to establish the multicomponent sequential metabolism (MSM) method based on comparative analysis along the digestive system following oral administration of licorice (Glycyrrhiza uralensis Fisch., leguminosae), a traditional Chinese medicine widely used for harmonizing other ingredients in a formulae. The licorice water extract (LWE) dissolved in Krebs-Ringer buffer solution (1 g/mL) was used to carry out the experiments and the comparative analysis was performed using HPLC and LC-MS/MS methods. In vitro incubation, in situ closed-loop and in vivo blood sampling were used to measure the LWE metabolic profile along the digestive system. The incubation experiment showed that the LWE was basically stable in digestive juice. A comparative analysis presented the metabolic profile of each prototype and its corresponding metabolites then. Liver was the major metabolic organ for LWE, and the metabolism by the intestinal flora and gut wall was also an important part of the process. The MSM method was practical and could be a potential method to describe the metabolic routes of multiple components before absorption into the systemic blood stream. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

  20. VIRTUAL MACHINES IN EDUCATION – CNC MILLING MACHINE WITH SINUMERIK 840D CONTROL SYSTEM

    Directory of Open Access Journals (Sweden)

    Ireneusz Zagórski

    2014-11-01

    Full Text Available Machining process nowadays could not be conducted without its inseparable element: cutting edge and frequently numerically controlled milling machines. Milling and lathe machining centres comprise standard equipment in many companies of the machinery industry, e.g. automotive or aircraft. It is for that reason that tertiary education should account for this rising demand. This entails the introduction into the curricula the forms which enable visualisation of machining, milling process and virtual production as well as virtual machining centres simulation. Siemens Virtual Machine (Virtual Workshop sets an example of such software, whose high functionality offers a range of learning experience, such as: learning the design of machine tools, their configuration, basic operation functions as well as basics of CNC.

  1. An investigative study towards constructing anthropocentric Man-Machine System design evaluation methodology

    International Nuclear Information System (INIS)

    Yoshikawa, H.; Gofuku, A.; Itoh, T.; Sasaki, K.

    1992-01-01

    A methodological investigation has been conducted for evaluating the reliability of man-machine interaction in the total Man-Machine System (MMS) from the view-point of safety maintenance for emergent situations of nuclear power plant. Basic considerations in our study are: (i) what are the MMS design data to be evaluated, (ii) how are those MMS design data should be treated, and (iii) how the introduction effects of various operator support tools can be evaluated. The methods of both qualitative and quantitative MMS design evaluation are summarized in this paper, with the system architecture based on man-machine interaction simulation and the related cognitive human error factor analysis. (author)

  2. Mechatronic sensor system for robots and automated machines

    CSIR Research Space (South Africa)

    Shaik, AA

    2007-01-01

    Full Text Available machine makes a calculated estimate of where the tool-head should be. This is often achieved by monitoring sensors on axes that track linear translation and rotations of shafts or gears. For low precision applications this system is appropriate. However...

  3. An intelligent man-machine system for future nuclear power plants

    International Nuclear Information System (INIS)

    Takizawa, Yoji; Hattori, Yoshiaki; Itoh, Juichiro; Fukumoto, Akira

    1994-01-01

    The objective of the development of an intelligent man-machine system for future nuclear power plants is enhancement of operational reliability by applying recent advances in cognitive science, artificial intelligence, and computer technologies. To realize this objective, the intelligent man-machine system, aiming to support a knowledge-based decision making process in an operator's supervisory plant control tasks, consists of three main functions, i.e., a cognitive model-based advisor, a robust automatic sequence controller, and an ecological interface. These three functions have been integrated into a console-type nuclear power plant monitoring and control system as a validation test bed. The validation tests in which experienced operator crews participated were carried out in 1991 and 1992. The test results show the usefulness of the support functions and the validity of the system design approach

  4. A machine vision system for the calibration of digital thermometers

    International Nuclear Information System (INIS)

    Vázquez-Fernández, Esteban; Dacal-Nieto, Angel; González-Jorge, Higinio; Alvarez-Valado, Victor; Martín, Fernando; Formella, Arno

    2009-01-01

    Automation is a key point in many industrial tasks such as calibration and metrology. In this context, machine vision has shown to be a useful tool for automation support, especially when there is no other option available. A system for the calibration of portable measurement devices has been developed. The system uses machine vision to obtain the numerical values shown by displays. A new approach based on human perception of digits, which works in parallel with other more classical classifiers, has been created. The results show the benefits of the system in terms of its usability and robustness, obtaining a success rate higher than 99% in display recognition. The system saves time and effort, and offers the possibility of scheduling calibration tasks without excessive attention by the laboratory technicians

  5. INTEGRATING MACHINE TRANSLATION AND SPEECH SYNTHESIS COMPONENT FOR ENGLISH TO DRAVIDIAN LANGUAGE SPEECH TO SPEECH TRANSLATION SYSTEM

    Directory of Open Access Journals (Sweden)

    J. SANGEETHA

    2015-02-01

    Full Text Available This paper provides an interface between the machine translation and speech synthesis system for converting English speech to Tamil text in English to Tamil speech to speech translation system. The speech translation system consists of three modules: automatic speech recognition, machine translation and text to speech synthesis. Many procedures for incorporation of speech recognition and machine translation have been projected. Still speech synthesis system has not yet been measured. In this paper, we focus on integration of machine translation and speech synthesis, and report a subjective evaluation to investigate the impact of speech synthesis, machine translation and the integration of machine translation and speech synthesis components. Here we implement a hybrid machine translation (combination of rule based and statistical machine translation and concatenative syllable based speech synthesis technique. In order to retain the naturalness and intelligibility of synthesized speech Auto Associative Neural Network (AANN prosody prediction is used in this work. The results of this system investigation demonstrate that the naturalness and intelligibility of the synthesized speech are strongly influenced by the fluency and correctness of the translated text.

  6. Viscoelastic machine elements elastomers and lubricants in machine systems

    CERN Document Server

    MOORE, D F

    2015-01-01

    Viscoelastic Machine Elements, which encompass elastomeric elements (rubber-like components), fluidic elements (lubricating squeeze films) and their combinations, are used for absorbing vibration, reducing friction and improving energy use. Examplesinclude pneumatic tyres, oil and lip seals, compliant bearings and races, and thin films. This book sets out to show that these elements can be incorporated in machine analysis, just as in the case of conventional elements (e.g. gears, cogs, chaindrives, bearings). This is achieved by introducing elementary theory and models, by describing new an

  7. Dynamics and Thermodynamics of Molecular Machines

    DEFF Research Database (Denmark)

    Golubeva, Natalia

    2014-01-01

    to their microscopic size, molecular motors are governed by principles fundamentally different from those describing the operation of man-made motors such as car engines. In this dissertation the dynamic and thermodynamic properties of molecular machines are studied using the tools of nonequilibrium statistical......Molecular machines, or molecular motors, are small biophysical devices that perform a variety of essential metabolic processes such as DNA replication, protein synthesis and intracellular transport. Typically, these machines operate by converting chemical energy into motion and mechanical work. Due...... mechanics. The first part focuses on noninteracting molecular machines described by a paradigmatic continuum model with the aim of comparing and contrasting such a description to the one offered by the widely used discrete models. Many molecular motors, for example, kinesin involved in cellular cargo...

  8. RESONANCE BEHAVIOUR ANALYSIS OF CARRYING SYSTEM IN HEAVY MACHINE WITH TRAVELING-COLUMN

    Directory of Open Access Journals (Sweden)

    Yu. V. Vasilevich

    2015-01-01

    Full Text Available A finite elements method (FEM-analysis has been carried out with the purpose to study dynamics of carrying system in a machine tool of unique height. This is a one-off machine with high traveling column and a support with horizontal slide can move vertically along the column. Spindle milling and boring units are mounted telescopically at slide butt end. The FEM-analysis of the machine tool has been made due to its renovation. Machine resonances, responses to cutting force, static and dynamic rigidity in spindles have been estimated in the paper. The machine carrying system is subtle, heavy and structurally complicated. Its structural chain includes a carriage, a column, a support, a slide, spindle units interconnected with the help of hydro-static guides. While varying main parameters their influence on rigidity has been investigated in the paper. Height of  support lifting, column material and rigidity of longitudinal drive have been changed during the investigations.Static, modal and harmonic MEF-analyses have been executed in the paper. Frequency-response characteristic of the machine has been constructed in the process of the investigations. Two support bending resonances have been detected in the column at low frequency. Such Due to this there are limits for usage of the machine in sub-resonance and static frequency range. The most powerful resonance has been observed at frequency of 27.8 Hz. The resonance has manifested itself as torsional oscillations of the column together with the support and the slide.Slide bending resonances have been revealed at higher frequencies 65–105 Hz. Three intervals which are fit for machine operation have been determined between resonance ranges. There is a prospective usage of the machine in inter-resonance (32–65 Hz and super-resonance (more than 105 Hz intervals. It has been shown that rigidity in spindle is a sequence higher in dynamic intervals than in a static interval. Machine subtility can be

  9. The Design and Realization of Virtual Machine of Embedded Soft PLC Running System

    Directory of Open Access Journals (Sweden)

    Qingzhao Zeng

    2014-11-01

    Full Text Available Currently soft PLC has been the focus of study object for many countries. Soft PLC system consists of the developing system and running system. A Virtual Machine is an important part in running system even in the whole soft PLC system. It explains and performs intermediate code generated by the developing system and updates I/O status of PLC in order to complete its control function. This paper introduced the implementation scheme and execution process of the embedded soft PLC running system Virtual Machine, and mainly introduced its software implementation method, including the realization of the input sampling program, the realization of the instruction execution program and the realization of output refresh program. Besides, an operation code matching method was put forward in the instruction execution program design. Finally, the test takes PowerPC/P1010 (Freescale as the hardware platform and Vxworks as the operating system, the system test result shows that accuracy, the real-time performance and reliability of Virtual Machine.

  10. Tool management in manufacturing systems equipped with CNC machines

    Directory of Open Access Journals (Sweden)

    Giovanni Tani

    1997-12-01

    Full Text Available This work has been carried out for the purpose of realizing an automated system for the integrated management of tools within a company. By integrating planning, inspection and tool-room functions, automated tool management can ensure optimum utilization of tools on the selected machines, guaranteeing their effective availability. The first stage of the work consisted of defining and developing a Tool Management System whose central nucleus is a unified Data Base for all of the tools, forming part of the company's Technological Files (files on machines, materials, equipment, methods, etc., interfaceable with all of the company departments that require information on tools. The system assigns code numbers to the individual components of the tools and file them on the basis of their morphological and functional characteristics. The system is also designed to effect assemblies of tools, from which are obtained the "Tool Cards" required for compiling working cycles (CAPP, for CAM programming and for the Tool-room where the tools are physically prepared. Methods for interfacing with suitable systems for the aforesaid functions have also been devised

  11. Human machine interface for research reactor instrumentation and control system

    International Nuclear Information System (INIS)

    Mohd Sabri Minhat; Mohd Idris Taib; Izhar Abu Hussin; Zareen Khan Abdul Jalil Khan; Nurfarhana Ayuni Joha

    2010-01-01

    Most present design of Human Machine Interface for Research Reactor Instrumentation and Control System is modular-based, comprise of several cabinets such as Reactor Protection System, Control Console, Information Console as well as Communication Console. The safety, engineering and human factor will be concerned for the design. Redundancy and separation of signal and power supply are the main factor for safety consideration. The design of Operator Interface absolutely takes consideration of human and environmental factors. Physical parameters, experiences, trainability and long-established habit patterns are very important for user interface, instead of the Aesthetic and Operator-Interface Geometry. Physical design for New Instrumentation and Control System of RTP are proposed base on the state-of- the-art Human Machine Interface design. (author)

  12. MACHINE LEARNING FOR THE SELF-ORGANIZATION OF DISTRIBUTED SYSTEMS IN ECONOMIC APPLICATIONS

    OpenAIRE

    Jerzy Balicki; Waldemar Korłub

    2017-01-01

    In this paper, an application of machine learning to the problem of self-organization of distributed systems has been discussed with regard to economic applications, with particular emphasis on supervised neural network learning to predict stock investments and some ratings of companies. In addition, genetic programming can play an important role in the preparation and testing of several financial information systems. For this reason, machine learning applications have been discussed because ...

  13. Distributed Control System Design for Portable PC Based CNC Machine

    Directory of Open Access Journals (Sweden)

    Roni Permana Saputra

    2014-07-01

    Full Text Available The demand on automated machining has been increased and emerges improvement research to achieve many goals such as portability, low cost manufacturability, interoperability, and simplicity in machine usage. These improvements are conducted without ignoring the performance analysis and usability evaluation. This research has designed a distributed control system in purpose to control a portable CNC machine. The design consists of main processing unit, secondary processing unit, motor control, and motor driver. A preliminary simulation has been conducted for performance analysis including linear accuracy and circular accuracy. The results achieved in the simulation provide linear accuracy up to 2 μm with total cost for the whole processing unit is up to 5 million IDR.

  14. Electric field prediction for a human body-electric machine system.

    Science.gov (United States)

    Ioannides, Maria G; Papadopoulos, Peter J; Dimitropoulou, Eugenia

    2004-01-01

    A system consisting of an electric machine and a human body is studied and the resulting electric field is predicted. A 3-phase induction machine operating at full load is modeled considering its geometry, windings, and materials. A human model is also constructed approximating its geometry and the electric properties of tissues. Using the finite element technique the electric field distribution in the human body is determined for a distance of 1 and 5 m from the machine and its effects are studied. Particularly, electric field potential variations are determined at specific points inside the human body and for these points the electric field intensity is computed and compared to the limit values for exposure according to international standards.

  15. Metabolic learning and memory formation by the brain influence systemic metabolic homeostasis

    Science.gov (United States)

    Zhang, Yumin; Liu, Gang; Yan, Jingqi; Zhang, Yalin; Li, Bo; Cai, Dongsheng

    2015-01-01

    Metabolic homeostasis is regulated by the brain, whether this regulation involves learning and memory of metabolic information remains unexplored. Here we use a calorie-based, taste-independent learning/memory paradigm to show that Drosophila form metabolic memories that help balancing food choice with caloric intake; however, this metabolic learning or memory is lost under chronic high-calorie feeding. We show that loss of individual learning/memory-regulating genes causes a metabolic learning defect, leading to elevated trehalose and lipids levels. Importantly, this function of metabolic learning requires not only the mushroom body but the hypothalamus-like pars intercerebralis, while NF-κB activation in the pars intercerebralis mimics chronic overnutrition in that it causes metabolic learning impairment and disorders. Finally, we evaluate this concept of metabolic learning/memory in mice, suggesting the hypothalamus is involved in a form of nutritional learning and memory, which is critical for determining resistance or susceptibility to obesity. In conclusion, our data indicate the brain, and potentially the hypothalamus, direct metabolic learning and the formation of memories, which contribute to the control of systemic metabolic homeostasis. PMID:25848677

  16. Quantification of human error and common-mode failures in man-machine systems

    International Nuclear Information System (INIS)

    Lisboa, J.J.

    1988-01-01

    Quantification of human performance, particularly the determination of human error, is essential for realistic assessment of overall system performance of man-machine systems. This paper presents an analysis of human errors in nuclear power plant systems when measured against common-mode failures (CMF). Human errors evaluated are improper testing, inadequate maintenance strategy, and miscalibration. The methodology presented in the paper represents a positive contribution to power plant systems availability by identifying sources of common-mode failure when operational functions are involved. It is also applicable to other complex systems such as chemical plants, aircraft and motor industries; in fact, any large man-created, man-machine system could be included

  17. Fuel handling machine and auxiliary systems for a fuel handling cell

    International Nuclear Information System (INIS)

    Suikki, M.

    2013-10-01

    This working report is an update for as well as a supplement to an earlier fuel handling machine design (Kukkola and Roennqvist 2006). A focus in the earlier design proposal was primarily on the selection of a mechanical structure and operating principle for the fuel handling machine. This report introduces not only a fuel handling machine design but also auxiliary fuel handling cell equipment and its operation. An objective of the design work was to verify the operating principles of and space allocations for fuel handling cell equipment. The fuel handling machine is a remote controlled apparatus capable of handling intensely radiating fuel assemblies in the fuel handling cell of an encapsulation plant. The fuel handling cell is air tight space radiation-shielded with massive concrete walls. The fuel handling machine is based on a bridge crane capable of traveling in the handling cell along wall tracks. The bridge crane has its carriage provided with a carousel type turntable having mounted thereon both fixed and telescopic masts. The fixed mast has a gripper movable on linear guides for the transfer of fuel assemblies. The telescopic mast has a manipulator arm capable of maneuvering equipment present in the fuel handling cell, as well as conducting necessary maintenance and cleaning operations or rectifying possible fault conditions. The auxiliary fuel handling cell systems consist of several subsystems. The subsystems include a service manipulator, a tool carrier for manipulators, a material hatch, assisting winches, a vacuum cleaner, as well as a hose reel. With the exception of the vacuum cleaner, the devices included in the fuel handling cell's auxiliary system are only used when the actual encapsulation process is not ongoing. The malfunctions of mechanisms or actuators responsible for the motion actions of a fuel handling machine preclude in a worst case scenario the bringing of the fuel handling cell and related systems to a condition appropriate for

  18. Fuel handling machine and auxiliary systems for a fuel handling cell

    Energy Technology Data Exchange (ETDEWEB)

    Suikki, M. [Optimik Oy, Turku (Finland)

    2013-10-15

    This working report is an update for as well as a supplement to an earlier fuel handling machine design (Kukkola and Roennqvist 2006). A focus in the earlier design proposal was primarily on the selection of a mechanical structure and operating principle for the fuel handling machine. This report introduces not only a fuel handling machine design but also auxiliary fuel handling cell equipment and its operation. An objective of the design work was to verify the operating principles of and space allocations for fuel handling cell equipment. The fuel handling machine is a remote controlled apparatus capable of handling intensely radiating fuel assemblies in the fuel handling cell of an encapsulation plant. The fuel handling cell is air tight space radiation-shielded with massive concrete walls. The fuel handling machine is based on a bridge crane capable of traveling in the handling cell along wall tracks. The bridge crane has its carriage provided with a carousel type turntable having mounted thereon both fixed and telescopic masts. The fixed mast has a gripper movable on linear guides for the transfer of fuel assemblies. The telescopic mast has a manipulator arm capable of maneuvering equipment present in the fuel handling cell, as well as conducting necessary maintenance and cleaning operations or rectifying possible fault conditions. The auxiliary fuel handling cell systems consist of several subsystems. The subsystems include a service manipulator, a tool carrier for manipulators, a material hatch, assisting winches, a vacuum cleaner, as well as a hose reel. With the exception of the vacuum cleaner, the devices included in the fuel handling cell's auxiliary system are only used when the actual encapsulation process is not ongoing. The malfunctions of mechanisms or actuators responsible for the motion actions of a fuel handling machine preclude in a worst case scenario the bringing of the fuel handling cell and related systems to a condition appropriate for

  19. Computerised weld strength testing machine for PHWR fuel elements with a versatile control system

    International Nuclear Information System (INIS)

    Gupta, U.C.; Sastry, V.S.; Rasheed, Jawad; Bibawe, S.R.

    1994-01-01

    Spacer pads and bearing pads are resistance spot welded on PHWR fuel elements to ensure inter-element gap for coolant flow. These welds are subjected to destructive tests as per SQC specifications while qualifying a machine and during production. The testing machine used earlier over the years was tedious involving manual operations of clamping, tool actuation, increasing and decreasing the pressure, referring to charts and statistical calculations. To carry out the destructive testing of the welds conveniently and reliably, an automatic machine is developed in-house in which are incorporated a quartz force transducer and a computerized data-acquisition and processing system together with a very versatile electronic control system based on a single-chip microcomputer. This paper describes the salient features of the machine and the control system. (author). 4 figs

  20. The Machine within the Machine

    CERN Multimedia

    Katarina Anthony

    2014-01-01

    Although Virtual Machines are widespread across CERN, you probably won't have heard of them unless you work for an experiment. Virtual machines - known as VMs - allow you to create a separate machine within your own, allowing you to run Linux on your Mac, or Windows on your Linux - whatever combination you need.   Using a CERN Virtual Machine, a Linux analysis software runs on a Macbook. When it comes to LHC data, one of the primary issues collaborations face is the diversity of computing environments among collaborators spread across the world. What if an institute cannot run the analysis software because they use different operating systems? "That's where the CernVM project comes in," says Gerardo Ganis, PH-SFT staff member and leader of the CernVM project. "We were able to respond to experimentalists' concerns by providing a virtual machine package that could be used to run experiment software. This way, no matter what hardware they have ...

  1. Protein design in systems metabolic engineering for industrial strain development.

    Science.gov (United States)

    Chen, Zhen; Zeng, An-Ping

    2013-05-01

    Accelerating the process of industrial bacterial host strain development, aimed at increasing productivity, generating new bio-products or utilizing alternative feedstocks, requires the integration of complementary approaches to manipulate cellular metabolism and regulatory networks. Systems metabolic engineering extends the concept of classical metabolic engineering to the systems level by incorporating the techniques used in systems biology and synthetic biology, and offers a framework for the development of the next generation of industrial strains. As one of the most useful tools of systems metabolic engineering, protein design allows us to design and optimize cellular metabolism at a molecular level. Here, we review the current strategies of protein design for engineering cellular synthetic pathways, metabolic control systems and signaling pathways, and highlight the challenges of this subfield within the context of systems metabolic engineering. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Design, development and evaluation of an online grading system for peeled pistachios equipped with machine vision technology and support vector machine

    Directory of Open Access Journals (Sweden)

    Hosein Nouri-Ahmadabadi

    2017-12-01

    Full Text Available In this study, an intelligent system based on combined machine vision (MV and Support Vector Machine (SVM was developed for sorting of peeled pistachio kernels and shells. The system was composed of conveyor belt, lighting box, camera, processing unit and sorting unit. A color CCD camera was used to capture images. The images were digitalized by a capture card and transferred to a personal computer for further analysis. Initially, images were converted from RGB color space to HSV color ones. For segmentation of the acquired images, H-component in the HSV color space and Otsu thresholding method were applied. A feature vector containing 30 color features was extracted from the captured images. A feature selection method based on sensitivity analysis was carried out to select superior features. The selected features were presented to SVM classifier. Various SVM models having a different kernel function were developed and tested. The SVM model having cubic polynomial kernel function and 38 support vectors achieved the best accuracy (99.17% and then was selected to use in online decision-making unit of the system. By launching the online system, it was found that limiting factors of the system capacity were related to the hardware parts of the system (conveyor belt and pneumatic valves used in the sorting unit. The limiting factors led to a distance of 8 mm between the samples. The overall accuracy and capacity of the sorter were obtained 94.33% and 22.74 kg/h, respectively. Keywords: Pistachio kernel, Sorting, Machine vision, Sensitivity analysis, Support vector machine

  3. Machine Control System of Steady State Superconducting Tokamak-1

    Energy Technology Data Exchange (ETDEWEB)

    Masand, Harish, E-mail: harish@ipr.res.in; Kumar, Aveg; Bhandarkar, M.; Mahajan, K.; Gulati, H.; Dhongde, J.; Patel, K.; Chudasma, H.; Pradhan, S.

    2016-11-15

    Highlights: • Central Control System. • SST-1. • Machine Control System. - Abstract: Central Control System (CCS) of the Steady State Superconducting Tokamak-1 (SST-1) controls and monitors around 25 plant and experiment subsystems of SST-1 located remotely from the Central-Control room. Machine Control System (MCS) is a supervisory system that sits on the top of the CCS hierarchy and implements the CCS state diagram. MCS ensures the software interlock between the SST-1 subsystems with the CCS, any subsystem communication failure or its local error does not prohibit the execution of the MCS and in-turn the CCS operation. MCS also periodically monitors the subsystem’s status and their vital process parameters throughout the campaign. It also provides the platform for the Central Control operator to visualize and exchange remotely the operational and experimental configuration parameters with the sub-systems. MCS remains operational 24 × 7 from the commencement to the termination of the SST-1 campaign. The developed MCS has performed robustly and flawlessly during all the last campaigns of SST-1 carried out so far. This paper will describe various aspects of the development of MCS.

  4. Quantum machine learning.

    Science.gov (United States)

    Biamonte, Jacob; Wittek, Peter; Pancotti, Nicola; Rebentrost, Patrick; Wiebe, Nathan; Lloyd, Seth

    2017-09-13

    Fuelled by increasing computer power and algorithmic advances, machine learning techniques have become powerful tools for finding patterns in data. Quantum systems produce atypical patterns that classical systems are thought not to produce efficiently, so it is reasonable to postulate that quantum computers may outperform classical computers on machine learning tasks. The field of quantum machine learning explores how to devise and implement quantum software that could enable machine learning that is faster than that of classical computers. Recent work has produced quantum algorithms that could act as the building blocks of machine learning programs, but the hardware and software challenges are still considerable.

  5. Machine Vision Systems for Processing Hardwood Lumber and Logs

    Science.gov (United States)

    Philip A. Araman; Daniel L. Schmoldt; Tai-Hoon Cho; Dongping Zhu; Richard W. Conners; D. Earl Kline

    1992-01-01

    Machine vision and automated processing systems are under development at Virginia Tech University with support and cooperation from the USDA Forest Service. Our goals are to help U.S. hardwood producers automate, reduce costs, increase product volume and value recovery, and market higher value, more accurately graded and described products. Any vision system is...

  6. Machine Learning Control For Highly Reconfigurable High-Order Systems

    Science.gov (United States)

    2015-01-02

    calibration and applications,” Mechatronics and Embedded Systems and Applications (MESA), 2010 IEEE/ASME International Conference on, IEEE, 2010, pp. 38–43...AFRL-OSR-VA-TR-2015-0012 MACHINE LEARNING CONTROL FOR HIGHLY RECONFIGURABLE HIGH-ORDER SYSTEMS John Valasek TEXAS ENGINEERING EXPERIMENT STATION...DIMENSIONAL RECONFIGURABLE SYSTEMS FA9550-11-1-0302 Period of Performance 1 July 2011 – 29 September 2014 John Valasek Aerospace Engineering

  7. Metabolic learning and memory formation by the brain influence systemic metabolic homeostasis.

    Science.gov (United States)

    Zhang, Yumin; Liu, Gang; Yan, Jingqi; Zhang, Yalin; Li, Bo; Cai, Dongsheng

    2015-04-07

    Metabolic homeostasis is regulated by the brain, but whether this regulation involves learning and memory of metabolic information remains unexplored. Here we use a calorie-based, taste-independent learning/memory paradigm to show that Drosophila form metabolic memories that help in balancing food choice with caloric intake; however, this metabolic learning or memory is lost under chronic high-calorie feeding. We show that loss of individual learning/memory-regulating genes causes a metabolic learning defect, leading to elevated trehalose and lipid levels. Importantly, this function of metabolic learning requires not only the mushroom body but also the hypothalamus-like pars intercerebralis, while NF-κB activation in the pars intercerebralis mimics chronic overnutrition in that it causes metabolic learning impairment and disorders. Finally, we evaluate this concept of metabolic learning/memory in mice, suggesting that the hypothalamus is involved in a form of nutritional learning and memory, which is critical for determining resistance or susceptibility to obesity. In conclusion, our data indicate that the brain, and potentially the hypothalamus, direct metabolic learning and the formation of memories, which contribute to the control of systemic metabolic homeostasis.

  8. The simulation of man-machine interaction in NPPs: the system response analyser project

    International Nuclear Information System (INIS)

    Cacciabue, P.C.

    1990-01-01

    In this paper, the ongoing research at Joint Research Centre-Ispra on the simulation of man-machine interaction is reviewed with reference to the past experience of system modelling and to the advances of the technological world. These require the coalescence of mixed disciplines covering the fields of engineering, psychology and sociology. In particular, the complexity of man-machine systems with respect to safety analysis is depicted. The developments and issues in modelling humans and machines are discussed: the possibility of combining them through the System Response Analyser methodology is presented as a balanced to be applied when the objective is the study of safety of systems during abnormal sequences. The three analytical tools which constitute the body of system response analysis namely a quasi-classical simulation of the actual plant, a cognitive model of the operator activities and a driver model, are described. (author)

  9. Dynamic cellular manufacturing system considering machine failure and workload balance

    Science.gov (United States)

    Rabbani, Masoud; Farrokhi-Asl, Hamed; Ravanbakhsh, Mohammad

    2018-02-01

    Machines are a key element in the production system and their failure causes irreparable effects in terms of cost and time. In this paper, a new multi-objective mathematical model for dynamic cellular manufacturing system (DCMS) is provided with consideration of machine reliability and alternative process routes. In this dynamic model, we attempt to resolve the problem of integrated family (part/machine cell) formation as well as the operators' assignment to the cells. The first objective minimizes the costs associated with the DCMS. The second objective optimizes the labor utilization and, finally, a minimum value of the variance of workload between different cells is obtained by the third objective function. Due to the NP-hard nature of the cellular manufacturing problem, the problem is initially validated by the GAMS software in small-sized problems, and then the model is solved by two well-known meta-heuristic methods including non-dominated sorting genetic algorithm and multi-objective particle swarm optimization in large-scaled problems. Finally, the results of the two algorithms are compared with respect to five different comparison metrics.

  10. Toward human-centered man-machine system in nuclear power plants

    International Nuclear Information System (INIS)

    Tanabe, Fumiya

    1993-01-01

    The Japanese LWR power plants are classified into 4 categories, from the viewpoints of the control panel in central control room and the extent of automation. Their characteristics are outlined. The potential weaknesses indwelt in the conventional approaches are discussed; that are the loss of applicability to the unanticipated facts and the loss of morale of the operators. The need for the construction of human-centered man-machine system is emphasized in order to overcome these potential weaknesses. The most important features required for the system are, in short term, to support operators in dificulties, and at the same time, in long term, to assure the acquisition and conservation of the personnels' morale and potential to cope with the problems. The concepts of the 'ecological interface' and 'adaptive aiding' system are introduced as the design concepts for the human-centered man-machine system. (J.P.N.)

  11. Detecting System of Nested Hardware Virtual Machine Monitor

    Directory of Open Access Journals (Sweden)

    Artem Vladimirovich Iuzbashev

    2015-03-01

    Full Text Available Method of nested hardware virtual machine monitor detection was proposed in this work. The method is based on HVM timing attack. In case of HVM presence in system, the number of different instruction sequences execution time values will increase. We used this property as indicator in our detection.

  12. Chaotic Boltzmann machines

    Science.gov (United States)

    Suzuki, Hideyuki; Imura, Jun-ichi; Horio, Yoshihiko; Aihara, Kazuyuki

    2013-01-01

    The chaotic Boltzmann machine proposed in this paper is a chaotic pseudo-billiard system that works as a Boltzmann machine. Chaotic Boltzmann machines are shown numerically to have computing abilities comparable to conventional (stochastic) Boltzmann machines. Since no randomness is required, efficient hardware implementation is expected. Moreover, the ferromagnetic phase transition of the Ising model is shown to be characterised by the largest Lyapunov exponent of the proposed system. In general, a method to relate probabilistic models to nonlinear dynamics by derandomising Gibbs sampling is presented. PMID:23558425

  13. On the Safety of Machine Learning: Cyber-Physical Systems, Decision Sciences, and Data Products.

    Science.gov (United States)

    Varshney, Kush R; Alemzadeh, Homa

    2017-09-01

    Machine learning algorithms increasingly influence our decisions and interact with us in all parts of our daily lives. Therefore, just as we consider the safety of power plants, highways, and a variety of other engineered socio-technical systems, we must also take into account the safety of systems involving machine learning. Heretofore, the definition of safety has not been formalized in a machine learning context. In this article, we do so by defining machine learning safety in terms of risk, epistemic uncertainty, and the harm incurred by unwanted outcomes. We then use this definition to examine safety in all sorts of applications in cyber-physical systems, decision sciences, and data products. We find that the foundational principle of modern statistical machine learning, empirical risk minimization, is not always a sufficient objective. We discuss how four different categories of strategies for achieving safety in engineering, including inherently safe design, safety reserves, safe fail, and procedural safeguards can be mapped to a machine learning context. We then discuss example techniques that can be adopted in each category, such as considering interpretability and causality of predictive models, objective functions beyond expected prediction accuracy, human involvement for labeling difficult or rare examples, and user experience design of software and open data.

  14. Machine Protection

    International Nuclear Information System (INIS)

    Zerlauth, Markus; Schmidt, Rüdiger; Wenninger, Jörg

    2012-01-01

    The present architecture of the machine protection system is being recalled and the performance of the associated systems during the 2011 run will be briefly summarized. An analysis of the causes of beam dumps as well as an assessment of the dependability of the machine protection systems (MPS) itself is being presented. Emphasis will be given to events that risked exposing parts of the machine to damage. Further improvements and mitigations of potential holes in the protection systems will be evaluated along with their impact on the 2012 run. The role of rMPP during the various operational phases (commissioning, intensity ramp up, MDs...) will be discussed along with a proposal for the intensity ramp up for the start of beam operation in 2012

  15. Machine Protection

    Energy Technology Data Exchange (ETDEWEB)

    Zerlauth, Markus; Schmidt, Rüdiger; Wenninger, Jörg [European Organization for Nuclear Research, Geneva (Switzerland)

    2012-07-01

    The present architecture of the machine protection system is being recalled and the performance of the associated systems during the 2011 run will be briefly summarized. An analysis of the causes of beam dumps as well as an assessment of the dependability of the machine protection systems (MPS) itself is being presented. Emphasis will be given to events that risked exposing parts of the machine to damage. Further improvements and mitigations of potential holes in the protection systems will be evaluated along with their impact on the 2012 run. The role of rMPP during the various operational phases (commissioning, intensity ramp up, MDs...) will be discussed along with a proposal for the intensity ramp up for the start of beam operation in 2012.

  16. Machine Protection

    CERN Document Server

    Zerlauth, Markus; Wenninger, Jörg

    2012-01-01

    The present architecture of the machine protection system is being recalled and the performance of the associated systems during the 2011 run will be briefly summarized. An analysis of the causes of beam dumps as well as an assessment of the dependability of the machine protection systems (MPS) itself is being presented. Emphasis will be given to events that risked exposing parts of the machine to damage. Further improvements and mitigations of potential holes in the protection systems will be evaluated along with their impact on the 2012 run. The role of rMPP during the various operational phases (commissioning, intensity ramp up, MDs...) will be discussed along with a proposal for the intensity ramp up for the start of beam operation in 2012.

  17. Muscle as a “Mediator“ of Systemic Metabolism

    Science.gov (United States)

    Baskin, Kedryn K.; Winders, Benjamin R.; Olson, Eric N.

    2015-01-01

    Skeletal and cardiac muscles play key roles in the regulation of systemic energy homeostasis and display remarkable plasticity in their metabolic responses to caloric availability and physical activity. In this Perspective we discuss recent studies highlighting transcriptional mechanisms that govern systemic metabolism by striated muscles. We focus on the participation of the Mediator complex in this process, and suggest that tissue-specific regulation of Mediator subunits impacts metabolic homeostasis. PMID:25651178

  18. Soft computing in machine learning

    CERN Document Server

    Park, Jooyoung; Inoue, Atsushi

    2014-01-01

    As users or consumers are now demanding smarter devices, intelligent systems are revolutionizing by utilizing machine learning. Machine learning as part of intelligent systems is already one of the most critical components in everyday tools ranging from search engines and credit card fraud detection to stock market analysis. You can train machines to perform some things, so that they can automatically detect, diagnose, and solve a variety of problems. The intelligent systems have made rapid progress in developing the state of the art in machine learning based on smart and deep perception. Using machine learning, the intelligent systems make widely applications in automated speech recognition, natural language processing, medical diagnosis, bioinformatics, and robot locomotion. This book aims at introducing how to treat a substantial amount of data, to teach machines and to improve decision making models. And this book specializes in the developments of advanced intelligent systems through machine learning. It...

  19. Operator aid system for Dhruva fueling machine

    International Nuclear Information System (INIS)

    Misra, S.M.; Ramaswamy, L.R.; Gohel, N.; Bharadwaj, G.; Ranade, M.R.; Khadilkar, M.G.

    1997-01-01

    Systems with significant software contents are replacing the old hardware logic systems. These systems not only are versatile but are easy to make changes in the program. Extensive use of such systems in critical real-time operation environment warrants not only excessive training on simulators, documentation but also fault tolerant system to bring the operation to a safe state in case of error. With new graphic user software interface and advancement in personal computer hardware design, the dynamic status of the physical environment can be shown on the visual display at near real time. These visual aids along with the software covering all the interlocks aids an operator in his professional work. This paper highlights the operator aid system for Dhruva fueling machine. (author). 6 refs., 1 fig

  20. 1st International Conference on Machine Learning for Cyber Physical Systems and Industry 4.0

    CERN Document Server

    Beyerer, Jürgen

    2016-01-01

    The work presents new approaches to Machine Learning for Cyber Physical Systems, experiences and visions. It contains some selected papers from the international Conference ML4CPS – Machine Learning for Cyber Physical Systems, which was held in Lemgo, October 1-2, 2015. Cyber Physical Systems are characterized by their ability to adapt and to learn: They analyze their environment and, based on observations, they learn patterns, correlations and predictive models. Typical applications are condition monitoring, predictive maintenance, image processing and diagnosis. Machine Learning is the key technology for these developments.

  1. Cross-cultural Human-Machine-Systems: selected aspects of a cross-cultural system engineering; Interkulturelle Mensch-Maschine-Systeme: ausgewaehlte Aspekte einer interkulturellen Systemgestaltung

    Energy Technology Data Exchange (ETDEWEB)

    Roese, K. [Technische Univ. Kaiserslautern (Germany). AG Nutzergerechte Produktentwicklung

    2006-07-01

    Cross-cultural Human-Machine-Systems are one key factor for success in the global market era. Nowadays the machine producer have to offer their products worldwide. With the export to other nations they have to consider on the user behaviour in these other cultures. The analysis of cross-cultural user requirements and their integration into the product development process is a real chance to cape with these challenge. This paper describe two aspects of cross-cultural user aspects. It gives an impression of the complex and sometimes unknown cultural influencing factors and their impact on Human-Machine-System-Engineering. (orig.)

  2. Systems metabolic engineering in an industrial setting.

    Science.gov (United States)

    Sagt, Cees M J

    2013-03-01

    Systems metabolic engineering is based on systems biology, synthetic biology, and evolutionary engineering and is now also applied in industry. Industrial use of systems metabolic engineering focuses on strain and process optimization. Since ambitious yields, titers, productivities, and low costs are key in an industrial setting, the use of effective and robust methods in systems metabolic engineering is becoming very important. Major improvements in the field of proteomics and metabolomics have been crucial in the development of genome-wide approaches in strain and process development. This is accompanied by a rapid increase in DNA sequencing and synthesis capacity. These developments enable the use of systems metabolic engineering in an industrial setting. Industrial systems metabolic engineering can be defined as the combined use of genome-wide genomics, transcriptomics, proteomics, and metabolomics to modify strains or processes. This approach has become very common since the technology for generating large data sets of all levels of the cellular processes has developed quite fast into robust, reliable, and affordable methods. The main challenge and scope of this mini review is how to translate these large data sets in relevant biological leads which can be tested for strain or process improvements. Experimental setup, heterogeneity of the culture, and sample pretreatment are important issues which are easily underrated. In addition, the process of structuring, filtering, and visualization of data is important, but also, the availability of a genetic toolbox and equipment for medium/high-throughput fermentation is a key success factor. For an efficient bioprocess, all the different components in this process have to work together. Therefore, mutual tuning of these components is an important strategy.

  3. Ecological relationship analysis of the urban metabolic system of Beijing, China

    International Nuclear Information System (INIS)

    Li Shengsheng; Zhang Yan; Yang Zhifeng; Liu Hong; Zhang Jinyun

    2012-01-01

    Cities can be modelled as giant organisms, with their own metabolic processes, and can therefore be studied using the same tools used for biological metabolic systems. The complicated distribution of compartments within these systems and the functional relationships among them define the system's network structure. Taking Beijing as an example, we divided the city's internal system into metabolic compartments, then used ecological network analysis to calculate a comprehensive utility matrix for the flows between compartments within Beijing's metabolic system from 1998 to 2007 and to identify the corresponding functional relationships among the system's compartments. Our results show how ecological network analysis, utility analysis, and relationship analysis can be used to discover the implied ecological relationships within a metabolic system, thereby providing insights into the system's internal metabolic processes. Such analyses provide scientific support for urban ecological management. - Highlights: ► Urban metabolic processes can be analyzed by treating cities as superorganisms. ► We developed an ecological network model for an urban system. ► We studied the system's network relationships using ecological network analysis. ► We developed indices for judging the system's synergism and degree of stability. - Using Beijing as an example of an urban superorganism, we used ecological network analysis to describe the ecological relationships among the urban metabolic system's compartments.

  4. Man-Machine Integrated Design and Analysis System (MIDAS): Functional Overview

    Science.gov (United States)

    Corker, Kevin; Neukom, Christian

    1998-01-01

    Included in the series of screen print-outs illustrates the structure and function of the Man-Machine Integrated Design and Analysis System (MIDAS). Views into the use of the system and editors are featured. The use-case in this set of graphs includes the development of a simulation scenario.

  5. Development of Fractal Pattern Making Application using L-System for Enhanced Machine Controller

    Directory of Open Access Journals (Sweden)

    Gunawan Alexander A S

    2014-03-01

    Full Text Available One big issue facing the industry today is an automated machine lack of flexibility for customization because it is designed by the manufacturers based on certain standards. In this research, it is developed customized application software for CNC (Computer Numerically Controlled machines using open source platform. The application is enable us to create designs by means of fractal patterns using L-System, developed by turtle geometry interpretation and Python programming languages. The result of the application is the G-Code of fractal pattern formed by the method of L-System. In the experiment on the CNC machine, the G-Code of fractal pattern which involving the branching structure has been able to run well.

  6. Control of discrete event systems modeled as hierarchical state machines

    Science.gov (United States)

    Brave, Y.; Heymann, M.

    1991-01-01

    The authors examine a class of discrete event systems (DESs) modeled as asynchronous hierarchical state machines (AHSMs). For this class of DESs, they provide an efficient method for testing reachability, which is an essential step in many control synthesis procedures. This method utilizes the asynchronous nature and hierarchical structure of AHSMs, thereby illustrating the advantage of the AHSM representation as compared with its equivalent (flat) state machine representation. An application of the method is presented where an online minimally restrictive solution is proposed for the problem of maintaining a controlled AHSM within prescribed legal bounds.

  7. Overall design concepts for the APS storage ring machine protection system

    International Nuclear Information System (INIS)

    Lumpkin, A.; Fuja, R.; Votaw, A.; Wang, X.; Shu, D.; Stepp, J.; Arnold, N.; Nawrocki, G.; Decker, G.; Chung, Y.

    1995-01-01

    The basic design and status of the machine protection system for the Advanced Photon Source (APS) storage ring are discussed. The machine is passively safe to the bending magnet sources, but the high power of the insertion devices requires missteering conditions to be identified and the beam aborted in less than one millisecond. The basic aspects of waterflow, temperature, beam position, etc. monitoring are addressed. Initial commissioning of subsystems and sensors is statused

  8. Machine learning techniques for optical communication system optimization

    DEFF Research Database (Denmark)

    Zibar, Darko; Wass, Jesper; Thrane, Jakob

    In this paper, machine learning techniques relevant to optical communication are presented and discussed. The focus is on applying machine learning tools to optical performance monitoring and performance prediction.......In this paper, machine learning techniques relevant to optical communication are presented and discussed. The focus is on applying machine learning tools to optical performance monitoring and performance prediction....

  9. Stereoscopic Machine-Vision System Using Projected Circles

    Science.gov (United States)

    Mackey, Jeffrey R.

    2010-01-01

    A machine-vision system capable of detecting obstacles large enough to damage or trap a robotic vehicle is undergoing development. The system includes (1) a pattern generator that projects concentric circles of laser light forward onto the terrain, (2) a stereoscopic pair of cameras that are aimed forward to acquire images of the circles, (3) a frame grabber and digitizer for acquiring image data from the cameras, and (4) a single-board computer that processes the data. The system is being developed as a prototype of machine- vision systems to enable robotic vehicles ( rovers ) on remote planets to avoid craters, large rocks, and other terrain features that could capture or damage the vehicles. Potential terrestrial applications of systems like this one could include terrain mapping, collision avoidance, navigation of robotic vehicles, mining, and robotic rescue. This system is based partly on the same principles as those of a prior stereoscopic machine-vision system in which the cameras acquire images of a single stripe of laser light that is swept forward across the terrain. However, this system is designed to afford improvements over some of the undesirable features of the prior system, including the need for a pan-and-tilt mechanism to aim the laser to generate the swept stripe, ambiguities in interpretation of the single-stripe image, the time needed to sweep the stripe across the terrain and process the data from many images acquired during that time, and difficulty of calibration because of the narrowness of the stripe. In this system, the pattern generator does not contain any moving parts and need not be mounted on a pan-and-tilt mechanism: the pattern of concentric circles is projected steadily in the forward direction. The system calibrates itself by use of data acquired during projection of the concentric-circle pattern onto a known target representing flat ground. The calibration- target image data are stored in the computer memory for use as a

  10. Specified international joint research. Report for fiscal 1997 on the result of `Development of Machining Supporting System`; Kokusai tokutei kyodo kenkyu. `Kikai kako shien system no kaihatsu` 1997 nendo seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    On the basis of information obtained from actually performed designing of machines with the aid of computers, researches are conducted for the development of a system that automatically designs required machine tools, machining procedures, machining conditions, and tool paths. The research and development efforts made in fiscal 1997 are enumerated below. In the development of man-machine interfaces, one that integrates a machining procedure designing system, machining condition designing system, and a tool path designing system, all of which are subsystems belonging in a machining supporting system, is developed. In a system evaluation performed through actual machining, an interface between CAD (Computer-Aided Design) technology and a machining supporting system is evaluated, when machining is actually performed for experimentation in an environment in which a machining procedure designing system, machining condition designing system, tool path designing system, and CNC (Computerized Numerical Control) technology collaborate as integrated. As the result, the performance expected to be achieved at the beginning is realized. Two scientists of Russian Academy of Sciences are invited, and researches are conducted concerning knowledge processing technology. 20 refs., 21 figs., 10 tabs.

  11. Management system of ELHEP cluster machine for FEL photonics design

    Science.gov (United States)

    Zysik, Jacek; Poźniak, Krzysztof; Romaniuk, Ryszard

    2006-10-01

    A multipurpose, distributed MatLab calculations oriented, cluster machine was assembled in PERG/ELHEP laboratory at ISE/WUT. It is predicted mainly for advanced photonics and FPGA/DSP based systems design for Free Electron Laser. It will be used also for student projects for superconducting accelerator and FEL. Here we present one specific side of cluster design. For an intense, distributed daily work with the cluster, it is important to have a good interface and practical access to all machine resources. A complex management system was implemented in PERG laboratory. It helps all registered users to work using all necessary applications, communicate with other logged in people, check all the news and gather all necessary information about what is going on in the system, how it is utilized, etc. The system is also very practical for administrator purposes, it helps to keep controlling who is using the resources and for how long. It provides different privileges for different applications and many more. The system is introduced as a freeware, using open source code and can be modified by system operators or super-users who are interested in nonstandard system configuration.

  12. High Accuracy Nonlinear Control and Estimation for Machine Tool Systems

    DEFF Research Database (Denmark)

    Papageorgiou, Dimitrios

    Component mass production has been the backbone of industry since the second industrial revolution, and machine tools are producing parts of widely varying size and design complexity. The ever-increasing level of automation in modern manufacturing processes necessitates the use of more...... sophisticated machine tool systems that are adaptable to different workspace conditions, while at the same time being able to maintain very narrow workpiece tolerances. The main topic of this thesis is to suggest control methods that can maintain required manufacturing tolerances, despite moderate wear and tear....... The purpose is to ensure that full accuracy is maintained between service intervals and to advice when overhaul is needed. The thesis argues that quality of manufactured components is directly related to the positioning accuracy of the machine tool axes, and it shows which low level control architectures...

  13. Study on on-machine defects measuring system on high power laser optical elements

    Science.gov (United States)

    Luo, Chi; Shi, Feng; Lin, Zhifan; Zhang, Tong; Wang, Guilin

    2017-10-01

    The influence of surface defects on high power laser optical elements will cause some harm to the performances of imaging system, including the energy consumption and the damage of film layer. To further increase surface defects on high power laser optical element, on-machine defects measuring system was investigated. Firstly, the selection and design are completed by the working condition analysis of the on-machine defects detection system. By designing on processing algorithms to realize the classification recognition and evaluation of surface defects. The calibration experiment of the scratch was done by using the self-made standard alignment plate. Finally, the detection and evaluation of surface defects of large diameter semi-cylindrical silicon mirror are realized. The calibration results show that the size deviation is less than 4% that meet the precision requirement of the detection of the defects. Through the detection of images the on-machine defects detection system can realize the accurate identification of surface defects.

  14. Methods, systems and apparatus for controlling operation of two alternating current (AC) machines

    Science.gov (United States)

    Gallegos-Lopez, Gabriel [Torrance, CA; Nagashima, James M [Cerritos, CA; Perisic, Milun [Torrance, CA; Hiti, Silva [Redondo Beach, CA

    2012-02-14

    A system is provided for controlling two AC machines. The system comprises a DC input voltage source that provides a DC input voltage, a voltage boost command control module (VBCCM), a five-phase PWM inverter module coupled to the two AC machines, and a boost converter coupled to the inverter module and the DC input voltage source. The boost converter is designed to supply a new DC input voltage to the inverter module having a value that is greater than or equal to a value of the DC input voltage. The VBCCM generates a boost command signal (BCS) based on modulation indexes from the two AC machines. The BCS controls the boost converter such that the boost converter generates the new DC input voltage in response to the BCS. When the two AC machines require additional voltage that exceeds the DC input voltage required to meet a combined target mechanical power required by the two AC machines, the BCS controls the boost converter to drive the new DC input voltage generated by the boost converter to a value greater than the DC input voltage.

  15. Machine Learning

    Energy Technology Data Exchange (ETDEWEB)

    Chikkagoudar, Satish; Chatterjee, Samrat; Thomas, Dennis G.; Carroll, Thomas E.; Muller, George

    2017-04-21

    The absence of a robust and unified theory of cyber dynamics presents challenges and opportunities for using machine learning based data-driven approaches to further the understanding of the behavior of such complex systems. Analysts can also use machine learning approaches to gain operational insights. In order to be operationally beneficial, cybersecurity machine learning based models need to have the ability to: (1) represent a real-world system, (2) infer system properties, and (3) learn and adapt based on expert knowledge and observations. Probabilistic models and Probabilistic graphical models provide these necessary properties and are further explored in this chapter. Bayesian Networks and Hidden Markov Models are introduced as an example of a widely used data driven classification/modeling strategy.

  16. Recent advances in systems metabolic engineering tools and strategies.

    Science.gov (United States)

    Chae, Tong Un; Choi, So Young; Kim, Je Woong; Ko, Yoo-Sung; Lee, Sang Yup

    2017-10-01

    Metabolic engineering has been playing increasingly important roles in developing microbial cell factories for the production of various chemicals and materials to achieve sustainable chemical industry. Nowadays, many tools and strategies are available for performing systems metabolic engineering that allows systems-level metabolic engineering in more sophisticated and diverse ways by adopting rapidly advancing methodologies and tools of systems biology, synthetic biology and evolutionary engineering. As an outcome, development of more efficient microbial cell factories has become possible. Here, we review recent advances in systems metabolic engineering tools and strategies together with accompanying application examples. In addition, we describe how these tools and strategies work together in simultaneous and synergistic ways to develop novel microbial cell factories. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Advancing metabolic engineering through systems biology of industrial microorganisms

    DEFF Research Database (Denmark)

    Dai, Zongjie; Nielsen, Jens

    2015-01-01

    resources. The objective of systems biology is to gain a comprehensive and quantitative understanding of living cells and can hereby enhance our ability to characterize and predict cellular behavior. Systems biology of industrial microorganisms is therefore valuable for metabolic engineering. Here we review......Development of sustainable processes to produce bio-based compounds is necessary due to the severe environmental problems caused by the use of fossil resources. Metabolic engineering can facilitate the development of highly efficient cell factories to produce these compounds from renewable...... the application of systems biology tools for the identification of metabolic engineering targets which may lead to reduced development time for efficient cell factories. Finally, we present some perspectives of systems biology for advancing metabolic engineering further....

  18. Design and Assessment of a Machine Vision System for Automatic Vehicle Wheel Alignment

    Directory of Open Access Journals (Sweden)

    Rocco Furferi

    2013-05-01

    Full Text Available Abstract Wheel alignment, consisting of properly checking the wheel characteristic angles against vehicle manufacturers' specifications, is a crucial task in the automotive field since it prevents irregular tyre wear and affects vehicle handling and safety. In recent years, systems based on Machine Vision have been widely studied in order to automatically detect wheels' characteristic angles. In order to overcome the limitations of existing methodologies, due to measurement equipment being mounted onto the wheels, the present work deals with design and assessment of a 3D machine vision-based system for the contactless reconstruction of vehicle wheel geometry, with particular reference to characteristic planes. Such planes, properly referred to as a global coordinate system, are used for determining wheel angles. The effectiveness of the proposed method was tested against a set of measurements carried out using a commercial 3D scanner; the absolute average error in measuring toe and camber angles with the machine vision system resulted in full compatibility with the expected accuracy of wheel alignment systems.

  19. Differentiation of Enhancing Glioma and Primary Central Nervous System Lymphoma by Texture-Based Machine Learning.

    Science.gov (United States)

    Alcaide-Leon, P; Dufort, P; Geraldo, A F; Alshafai, L; Maralani, P J; Spears, J; Bharatha, A

    2017-06-01

    Accurate preoperative differentiation of primary central nervous system lymphoma and enhancing glioma is essential to avoid unnecessary neurosurgical resection in patients with primary central nervous system lymphoma. The purpose of the study was to evaluate the diagnostic performance of a machine-learning algorithm by using texture analysis of contrast-enhanced T1-weighted images for differentiation of primary central nervous system lymphoma and enhancing glioma. Seventy-one adult patients with enhancing gliomas and 35 adult patients with primary central nervous system lymphomas were included. The tumors were manually contoured on contrast-enhanced T1WI, and the resulting volumes of interest were mined for textural features and subjected to a support vector machine-based machine-learning protocol. Three readers classified the tumors independently on contrast-enhanced T1WI. Areas under the receiver operating characteristic curves were estimated for each reader and for the support vector machine classifier. A noninferiority test for diagnostic accuracy based on paired areas under the receiver operating characteristic curve was performed with a noninferiority margin of 0.15. The mean areas under the receiver operating characteristic curve were 0.877 (95% CI, 0.798-0.955) for the support vector machine classifier; 0.878 (95% CI, 0.807-0.949) for reader 1; 0.899 (95% CI, 0.833-0.966) for reader 2; and 0.845 (95% CI, 0.757-0.933) for reader 3. The mean area under the receiver operating characteristic curve of the support vector machine classifier was significantly noninferior to the mean area under the curve of reader 1 ( P = .021), reader 2 ( P = .035), and reader 3 ( P = .007). Support vector machine classification based on textural features of contrast-enhanced T1WI is noninferior to expert human evaluation in the differentiation of primary central nervous system lymphoma and enhancing glioma. © 2017 by American Journal of Neuroradiology.

  20. The application of state machine based on labview for solid target transfer control system at BATAN’s cyclotron

    International Nuclear Information System (INIS)

    Heranudin; Rajiman; Parwanto; Edy Slamet R

    2015-01-01

    Software programming for the new solid target transfer control system referred to the working principle of the whole each sub system. System modeling with state machine diagram was chosen because this simplified a complex design of the control system. State machine implementation of this system was performed by creating basic state drawn from the working system of each sub system. All states with their described inputs, outputs and algorithms were compiled in the sequential state machine diagram. In order to ease the operation, three modes namely automatic, major states and micro states were created. Testing of the system has been conducted and as a result, the system worked properly. The implementation of State machine based on LabView has several advantages such as faster, easier programming and the capability for further developments. (author)

  1. Study on intelligent processing system of man-machine interactive garment frame model

    Science.gov (United States)

    Chen, Shuwang; Yin, Xiaowei; Chang, Ruijiang; Pan, Peiyun; Wang, Xuedi; Shi, Shuze; Wei, Zhongqian

    2018-05-01

    A man-machine interactive garment frame model intelligent processing system is studied in this paper. The system consists of several sensor device, voice processing module, mechanical parts and data centralized acquisition devices. The sensor device is used to collect information on the environment changes brought by the body near the clothes frame model, the data collection device is used to collect the information of the environment change induced by the sensor device, voice processing module is used for speech recognition of nonspecific person to achieve human-machine interaction, mechanical moving parts are used to make corresponding mechanical responses to the information processed by data collection device.it is connected with data acquisition device by a means of one-way connection. There is a one-way connection between sensor device and data collection device, two-way connection between data acquisition device and voice processing module. The data collection device is one-way connection with mechanical movement parts. The intelligent processing system can judge whether it needs to interact with the customer, realize the man-machine interaction instead of the current rigid frame model.

  2. Advancing metabolic engineering through systems biology of industrial microorganisms.

    Science.gov (United States)

    Dai, Zongjie; Nielsen, Jens

    2015-12-01

    Development of sustainable processes to produce bio-based compounds is necessary due to the severe environmental problems caused by the use of fossil resources. Metabolic engineering can facilitate the development of highly efficient cell factories to produce these compounds from renewable resources. The objective of systems biology is to gain a comprehensive and quantitative understanding of living cells and can hereby enhance our ability to characterize and predict cellular behavior. Systems biology of industrial microorganisms is therefore valuable for metabolic engineering. Here we review the application of systems biology tools for the identification of metabolic engineering targets which may lead to reduced development time for efficient cell factories. Finally, we present some perspectives of systems biology for advancing metabolic engineering further. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Switchable reconfiguration of nucleic acid nanostructures by stimuli-responsive DNA machines.

    Science.gov (United States)

    Liu, Xiaoqing; Lu, Chun-Hua; Willner, Itamar

    2014-06-17

    catalytic nanoparticles. Exciting applications of these systems are ahead of us, and switchable catalytic nanoparticle systems, switchable enzyme cascades, and spatially programmed nanoparticles for innovative nanomedicine may be envisaged. Also, the intracellular reconfiguration of nucleic acids by stimuli-responsive DNA machines holds great promise as a means to silence genes or inhibit metabolic pathways.

  4. Human-Machine Systems concepts applied to Control Engineering Education

    OpenAIRE

    Marangé , Pascale; Gellot , François; Riera , Bernard

    2008-01-01

    International audience; In this paper, we interest us to Human-Machine Systems (HMS) concepts applied to Education. It is shown how the HMS framework enables to propose original solution in matter of education in the field of control engineering. We focus on practical courses on control of manufacturing systems. The proposed solution is based on an original use of real and large-scale systems instead of simulation. The main idea is to enable the student, whatever his/her level to control the ...

  5. Asynchronized synchronous machines

    CERN Document Server

    Botvinnik, M M

    1964-01-01

    Asynchronized Synchronous Machines focuses on the theoretical research on asynchronized synchronous (AS) machines, which are "hybrids” of synchronous and induction machines that can operate with slip. Topics covered in this book include the initial equations; vector diagram of an AS machine; regulation in cases of deviation from the law of full compensation; parameters of the excitation system; and schematic diagram of an excitation regulator. The possible applications of AS machines and its calculations in certain cases are also discussed. This publication is beneficial for students and indiv

  6. Advanced stability control of multi-machine power system by vips apparatus

    Energy Technology Data Exchange (ETDEWEB)

    Yokoyama, A [Tokyo Univ., Tokyo (Japan). Dept. of Electrical Engineering; Sekine, Y [Science Univ. of Tokyo, Tokyo (Japan). Dept. of Electrical Engineering

    1994-12-31

    New technology such as synchronized switching and power electronics will make it possible to change the configuration of transmission network, the impedances of transmission lines and the phase angles of voltage in the future power systems. This paper presents a comprehensive power system damping control by power electronics based variable impedance apparatus such as variable series capacitor and high speed phase shifter and also shows a novel switching-over control of transmission lines by synchronized switching for the first awing stability and damping enhancement. The control scheme discussed in this paper is based on an energy function of multi-machine power system and its time derivative. Its effectiveness is demonstrated by digital simulations and eigenvalue analysis in multi-machine test systems. It is demonstrated that multiple switching of transmission lines improves damping in the post-fault conditions. (author) 13 refs., 24 figs., 5 tabs.

  7. Standard practices for verification of displacement measuring systems and devices used in material testing machines

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2005-01-01

    1.1 These practices cover procedures and requirements for the calibration and verification of displacement measuring systems by means of standard calibration devices for static and quasi-static testing machines. This practice is not intended to be complete purchase specifications for testing machines or displacement measuring systems. Displacement measuring systems are not intended to be used for the determination of strain. See Practice E83. 1.2 These procedures apply to the verification of the displacement measuring systems associated with the testing machine, such as a scale, dial, marked or unmarked recorder chart, digital display, etc. In all cases the buyer/owner/user must designate the displacement-measuring system(s) to be verified. 1.3 The values stated in either SI units or inch-pound units are to be regarded separately as standard. The values stated in each system may not be exact equivalents; therefore, each system shall be used independently of the other. Combining values from the two systems m...

  8. Machine learning algorithms for the creation of clinical healthcare enterprise systems

    Science.gov (United States)

    Mandal, Indrajit

    2017-10-01

    Clinical recommender systems are increasingly becoming popular for improving modern healthcare systems. Enterprise systems are persuasively used for creating effective nurse care plans to provide nurse training, clinical recommendations and clinical quality control. A novel design of a reliable clinical recommender system based on multiple classifier system (MCS) is implemented. A hybrid machine learning (ML) ensemble based on random subspace method and random forest is presented. The performance accuracy and robustness of proposed enterprise architecture are quantitatively estimated to be above 99% and 97%, respectively (above 95% confidence interval). The study then extends to experimental analysis of the clinical recommender system with respect to the noisy data environment. The ranking of items in nurse care plan is demonstrated using machine learning algorithms (MLAs) to overcome the drawback of the traditional association rule method. The promising experimental results are compared against the sate-of-the-art approaches to highlight the advancement in recommendation technology. The proposed recommender system is experimentally validated using five benchmark clinical data to reinforce the research findings.

  9. A Multiple Sensor Machine Vision System for Automatic Hardwood Feature Detection

    Science.gov (United States)

    D. Earl Kline; Richard W. Conners; Daniel L. Schmoldt; Philip A. Araman; Robert L. Brisbin

    1993-01-01

    A multiple sensor machine vision prototype is being developed to scan full size hardwood lumber at industrial speeds for automatically detecting features such as knots holes, wane, stain, splits, checks, and color. The prototype integrates a multiple sensor imaging system, a materials handling system, a computer system, and application software. The prototype provides...

  10. Precision mechatronics based on high-precision measuring and positioning systems and machines

    Science.gov (United States)

    Jäger, Gerd; Manske, Eberhard; Hausotte, Tino; Mastylo, Rostyslav; Dorozhovets, Natalja; Hofmann, Norbert

    2007-06-01

    Precision mechatronics is defined in the paper as the science and engineering of a new generation of high precision systems and machines. Nanomeasuring and nanopositioning engineering represents important fields of precision mechatronics. The nanometrology is described as the today's limit of the precision engineering. The problem, how to design nanopositioning machines with uncertainties as small as possible will be discussed. The integration of several optical and tactile nanoprobes makes the 3D-nanopositioning machine suitable for various tasks, such as long range scanning probe microscopy, mask and wafer inspection, nanotribology, nanoindentation, free form surface measurement as well as measurement of microoptics, precision molds, microgears, ring gauges and small holes.

  11. Pointright: a system to redirect mouse and keyboard control among multiple machines

    Science.gov (United States)

    Johanson, Bradley E [Palo Alto, CA; Winograd, Terry A [Stanford, CA; Hutchins, Gregory M [Mountain View, CA

    2008-09-30

    The present invention provides a software system, PointRight, that allows for smooth and effortless control of pointing and input devices among multiple displays. With PointRight, a single free-floating mouse and keyboard can be used to control multiple screens. When the cursor reaches the edge of a screen it seamlessly moves to the adjacent screen and keyboard control is simultaneously redirected to the appropriate machine. Laptops may also redirect their keyboard and pointing device, and multiple pointers are supported simultaneously. The system automatically reconfigures itself as displays go on, go off, or change the machine they display.

  12. Machine Learning-based Intelligent Formal Reasoning and Proving System

    Science.gov (United States)

    Chen, Shengqing; Huang, Xiaojian; Fang, Jiaze; Liang, Jia

    2018-03-01

    The reasoning system can be used in many fields. How to improve reasoning efficiency is the core of the design of system. Through the formal description of formal proof and the regular matching algorithm, after introducing the machine learning algorithm, the system of intelligent formal reasoning and verification has high efficiency. The experimental results show that the system can verify the correctness of propositional logic reasoning and reuse the propositional logical reasoning results, so as to obtain the implicit knowledge in the knowledge base and provide the basic reasoning model for the construction of intelligent system.

  13. Machine Learning.

    Science.gov (United States)

    Kirrane, Diane E.

    1990-01-01

    As scientists seek to develop machines that can "learn," that is, solve problems by imitating the human brain, a gold mine of information on the processes of human learning is being discovered, expert systems are being improved, and human-machine interactions are being enhanced. (SK)

  14. Power quality in power systems and electrical machines

    CERN Document Server

    Fuchs, Ewald

    2015-01-01

    The second edition of this must-have reference covers power quality issues in four parts, including new discussions related to renewable energy systems. The first part of the book provides background on causes, effects, standards, and measurements of power quality and harmonics. Once the basics are established the authors move on to harmonic modeling of power systems, including components and apparatus (electric machines). The final part of the book is devoted to power quality mitigation approaches and devices, and the fourth part extends the analysis to power quality solutions for renewable

  15. On-line transient stability assessment of large-scale power systems by using ball vector machines

    International Nuclear Information System (INIS)

    Mohammadi, M.; Gharehpetian, G.B.

    2010-01-01

    In this paper ball vector machine (BVM) has been used for on-line transient stability assessment of large-scale power systems. To classify the system transient security status, a BVM has been trained for all contingencies. The proposed BVM based security assessment algorithm has very small training time and space in comparison with artificial neural networks (ANN), support vector machines (SVM) and other machine learning based algorithms. In addition, the proposed algorithm has less support vectors (SV) and therefore is faster than existing algorithms for on-line applications. One of the main points, to apply a machine learning method is feature selection. In this paper, a new Decision Tree (DT) based feature selection technique has been presented. The proposed BVM based algorithm has been applied to New England 39-bus power system. The simulation results show the effectiveness and the stability of the proposed method for on-line transient stability assessment procedure of large-scale power system. The proposed feature selection algorithm has been compared with different feature selection algorithms. The simulation results demonstrate the effectiveness of the proposed feature algorithm.

  16. Efficient Embedded Decoding of Neural Network Language Models in a Machine Translation System.

    Science.gov (United States)

    Zamora-Martinez, Francisco; Castro-Bleda, Maria Jose

    2018-02-22

    Neural Network Language Models (NNLMs) are a successful approach to Natural Language Processing tasks, such as Machine Translation. We introduce in this work a Statistical Machine Translation (SMT) system which fully integrates NNLMs in the decoding stage, breaking the traditional approach based on [Formula: see text]-best list rescoring. The neural net models (both language models (LMs) and translation models) are fully coupled in the decoding stage, allowing to more strongly influence the translation quality. Computational issues were solved by using a novel idea based on memorization and smoothing of the softmax constants to avoid their computation, which introduces a trade-off between LM quality and computational cost. These ideas were studied in a machine translation task with different combinations of neural networks used both as translation models and as target LMs, comparing phrase-based and [Formula: see text]-gram-based systems, showing that the integrated approach seems more promising for [Formula: see text]-gram-based systems, even with nonfull-quality NNLMs.

  17. Corynebacterium glutamicum for Sustainable Bioproduction: From Metabolic Physiology to Systems Metabolic Engineering.

    Science.gov (United States)

    Becker, Judith; Gießelmann, Gideon; Hoffmann, Sarah Lisa; Wittmann, Christoph

    Since its discovery 60 years ago, Corynebacterium glutamicum has evolved into a workhorse for industrial biotechnology. Traditionally well known for its remarkable capacity to produce amino acids, this Gram-positive soil bacterium, has become a flexible, efficient production platform for various bulk and fine chemicals, materials, and biofuels. The central turnstile of all these achievements is our excellent understanding of its metabolism and physiology. This knowledge base, together with innovative systems metabolic engineering concepts, which integrate systems and synthetic biology into strain engineering, has upgraded C. glutamicum into one of the most successful industrial microorganisms in the world.

  18. Trust between man and machine in a teleoperation system

    International Nuclear Information System (INIS)

    Dassonville, I.; Jolly, D.; Desodt, A.M.

    1996-01-01

    The work we present deals with the trust of man in a teleoperation system. Trust is important because it is linked to stress which modifies human reliability. We are trying to quantify trust. In this paper, we'll present the theory of trust in relationships, and its extension for a man-machine system. Then, we explain the links between trust and human reliability. Then, we introduce our experimental process and the first results concerning selfconfidence

  19. Study on the adjustment capability of the excitation system located inside superconducting machine electromagnetic shield

    Science.gov (United States)

    Xia, D.; Xia, Z.

    2017-12-01

    The ability for the excitation system to adjust quickly plays a very important role in maintaining the normal operation of superconducting machines and power systems. However, the eddy currents in the electromagnetic shield of superconducting machines hinder the exciting magnetic field change and weaken the adjustment capability of the excitation system. To analyze this problem, a finite element calculation model for the transient electromagnetic field with moving parts is established. The effects of three different electromagnetic shields on the exciting magnetic field are analyzed using finite element method. The results show that the electromagnetic shield hinders the field changes significantly, the better its conductivity, the greater the effect on the superconducting machine excitation.

  20. A generic finite state machine framework for the ACNET control system

    International Nuclear Information System (INIS)

    Carmichael, L.; Warner, A.

    2009-01-01

    A significant level of automation and flexibility has been added to the ACNET control system through the development of a Java-based Finite State Machine (FSM) infrastructure. These FSMs are integrated into ACNET and allow users to easily build, test and execute scripts that have full access to ACNET's functionality. In this paper, a description will be given of the FSM design and its ties to the Java-based Data Acquisition Engine (DAE) framework. Each FSM is part of a client-server model with FSM display clients using Remote Method Invocation (RMI) to communicate with DAE servers heavily coupled to ACNET. A web-based monitoring system that allows users to utilize browsers to observe persistent FSMs will also be discussed. Finally, some key implementations such as the crash recovery FSM developed for the Electron Cooling machine protection system will be presented.

  1. Failure Identification of Hacksaw Machine REMOR 400

    International Nuclear Information System (INIS)

    Paidjo; Abdul Hafid; Sagino

    2007-01-01

    REMOR 400 Hack sawing machine is one of machines type has been old age. For arrange of cutting pressure and repeat lifting load after cutting process by using the hydraulic system. Beside of worn-out of hacksaw blade, failure cutting earn also because of leakage from the hydraulic system of machine. Leakage of hydraulic system occurs because of over load factor using or aging. Base on inspection result, hacksaw machine REMOR 400 fault on hydraulic system in the 2006 year. This matter will be seen from its seal brittle from the machine. For activate to return machine so much replacement repeat the seals used by machine. (author)

  2. Abreu system - A dosimetric system to evaluate basic parameters of photofluorographic X-ray machine

    International Nuclear Information System (INIS)

    Feital, J.C.

    1987-01-01

    In Brazil, photofluorographic X-ray machines are used for cuberculosis mass screening throughout the country. The exact number of these X-ray equipment is unknown but it is estimated to be around 1000 operating units. Twelve million miniature chest radiographs are taken per year. In order to make local inspections speedier and also aiming at its postal use, a system has been developed wich evaluates the entrace exposure of the patient, the X-ray beam half-value layer ( leading to the evaluation of the tube's total filtration ) and the beam's field size. It consists of a piece of cardboard where filters, TLDs and X-ray films are inserted. So far the system has been tested in 53 X-ray machines in Rio de Janeiro. The results show that it can be used in a national survey program. (Author) [pt

  3. MITS machine operations

    International Nuclear Information System (INIS)

    Flinchem, J.

    1980-01-01

    This document contains procedures which apply to operations performed on individual P-1c machines in the Machine Interface Test System (MITS) at AiResearch Manufacturing Company's Torrance, California Facility

  4. Methods and systems for micro machines

    Energy Technology Data Exchange (ETDEWEB)

    Stalford, Harold L.

    2018-03-06

    A micro machine may be in or less than the micrometer domain. The micro machine may include a micro actuator and a micro shaft coupled to the micro actuator. The micro shaft is operable to be driven by the micro actuator. A tool is coupled to the micro shaft and is operable to perform work in response to at least motion of the micro shaft.

  5. Comparison of Three Smart Camera Architectures for Real-Time Machine Vision System

    Directory of Open Access Journals (Sweden)

    Abdul Waheed Malik

    2013-12-01

    Full Text Available This paper presents a machine vision system for real-time computation of distance and angle of a camera from a set of reference points located on a target board. Three different smart camera architectures were explored to compare performance parameters such as power consumption, frame speed and latency. Architecture 1 consists of hardware machine vision modules modeled at Register Transfer (RT level and a soft-core processor on a single FPGA chip. Architecture 2 is commercially available software based smart camera, Matrox Iris GT. Architecture 3 is a two-chip solution composed of hardware machine vision modules on FPGA and an external microcontroller. Results from a performance comparison show that Architecture 2 has higher latency and consumes much more power than Architecture 1 and 3. However, Architecture 2 benefits from an easy programming model. Smart camera system with FPGA and external microcontroller has lower latency and consumes less power as compared to single FPGA chip having hardware modules and soft-core processor.

  6. Analysis on machine tool systems using spindle vibration monitoring for automatic tool changer

    Directory of Open Access Journals (Sweden)

    Shang-Liang Chen

    2015-12-01

    Full Text Available Recently, the intelligent systems of technology have become one of the major items in the development of machine tools. One crucial technology is the machinery status monitoring function, which is required for abnormal warnings and the improvement of cutting efficiency. During processing, the mobility act of the spindle unit determines the most frequent and important part such as automatic tool changer. The vibration detection system includes the development of hardware and software, such as vibration meter, signal acquisition card, data processing platform, and machine control program. Meanwhile, based on the difference between the mechanical configuration and the desired characteristics, it is difficult for a vibration detection system to directly choose the commercially available kits. For this reason, it was also selected as an item for self-development research, along with the exploration of a significant parametric study that is sufficient to represent the machine characteristics and states. However, we also launched the development of functional parts of the system simultaneously. Finally, we entered the conditions and the parameters generated from both the states and the characteristics into the developed system to verify its feasibility.

  7. Ex-vivo machine perfusion for kidney preservation.

    Science.gov (United States)

    Hamar, Matyas; Selzner, Markus

    2018-06-01

    Machine perfusion is a novel strategy to decrease preservation injury, improve graft assessment, and increase organ acceptance for transplantation. This review summarizes the current advances in ex-vivo machine-based kidney preservation technologies over the last year. Ex-vivo perfusion technologies, such as hypothermic and normothermic machine perfusion and controlled oxygenated rewarming, have gained high interest in the field of organ preservation. Keeping kidney grafts functionally and metabolically active during the preservation period offers a unique chance for viability assessment, reconditioning, and organ repair. Normothermic ex-vivo kidney perfusion has been recently translated into clinical practice. Preclinical results suggest that prolonged warm perfusion appears superior than a brief end-ischemic reconditioning in terms of renal function and injury. An established standardized protocol for continuous warm perfusion is still not available for human grafts. Ex-vivo machine perfusion represents a superior organ preservation method over static cold storage. There is still an urgent need for the optimization of the perfusion fluid and machine technology and to identify the optimal indication in kidney transplantation. Recent research is focusing on graft assessment and therapeutic strategies.

  8. In silico machine learning methods in drug development.

    Science.gov (United States)

    Dobchev, Dimitar A; Pillai, Girinath G; Karelson, Mati

    2014-01-01

    Machine learning (ML) computational methods for predicting compounds with pharmacological activity, specific pharmacodynamic and ADMET (absorption, distribution, metabolism, excretion and toxicity) properties are being increasingly applied in drug discovery and evaluation. Recently, machine learning techniques such as artificial neural networks, support vector machines and genetic programming have been explored for predicting inhibitors, antagonists, blockers, agonists, activators and substrates of proteins related to specific therapeutic targets. These methods are particularly useful for screening compound libraries of diverse chemical structures, "noisy" and high-dimensional data to complement QSAR methods, and in cases of unavailable receptor 3D structure to complement structure-based methods. A variety of studies have demonstrated the potential of machine-learning methods for predicting compounds as potential drug candidates. The present review is intended to give an overview of the strategies and current progress in using machine learning methods for drug design and the potential of the respective model development tools. We also regard a number of applications of the machine learning algorithms based on common classes of diseases.

  9. Social Intelligence in a Human-Machine Collaboration System

    Science.gov (United States)

    Nakajima, Hiroshi; Morishima, Yasunori; Yamada, Ryota; Brave, Scott; Maldonado, Heidy; Nass, Clifford; Kawaji, Shigeyasu

    In this information society of today, it is often argued that it is necessary to create a new way of human-machine interaction. In this paper, an agent with social response capabilities has been developed to achieve this goal. There are two kinds of information that is exchanged by two entities: objective and functional information (e.g., facts, requests, states of matters, etc.) and subjective information (e.g., feelings, sense of relationship, etc.). Traditional interactive systems have been designed to handle the former kind of information. In contrast, in this study social agents handling the latter type of information are presented. The current study focuses on sociality of the agent from the view point of Media Equation theory. This article discusses the definition, importance, and benefits of social intelligence as agent technology and argues that social intelligence has a potential to enhance the user's perception of the system, which in turn can lead to improvements of the system's performance. In order to implement social intelligence in the agent, a mind model has been developed to render affective expressions and personality of the agent. The mind model has been implemented in a human-machine collaborative learning system. One differentiating feature of the collaborative learning system is that it has an agent that performs as a co-learner with which the user interacts during the learning session. The mind model controls the social behaviors of the agent, thus making it possible for the user to have more social interactions with the agent. The experiment with the system suggested that a greater degree of learning was achieved when the students worked with the co-learner agent and that the co-learner agent with the mind model that expressed emotions resulted in a more positive attitude toward the system.

  10. Direct numerical control of machine tools in a nuclear research center by the CAMAC system

    International Nuclear Information System (INIS)

    Zwoll, K.; Mueller, K.D.; Becks, B.; Erven, W.; Sauer, M.

    1977-01-01

    The production of mechanical parts in research centers can be improved by connecting several numerically controlled machine tools to a central process computer via a data link. The CAMAC Serial Highway with its expandable structure yields an economic and flexible system for this purpose. The CAMAC System also facilitates the development of modular components controlling the machine tools itself. A CAMAC installation controlling three different machine tools connected to a central computer (PDP11) via the CAMAC Serial Highway is described. Besides this application, part of the CAMAC hardware and software can also be used for a great variety of scientific experiments

  11. Modelling open pit shovel-truck systems using the Machine Repair Model

    Energy Technology Data Exchange (ETDEWEB)

    Krause, A.; Musingwini, C. [CBH Resources Ltd., Sydney, NSW (Australia). Endeaver Mine

    2007-08-15

    Shovel-truck systems for loading and hauling material in open pit mines are now routinely analysed using simulation models or off-the-shelf simulation software packages, which can be very expensive for once-off or occasional use. The simulation models invariably produce different estimations of fleet sizes due to their differing estimations of cycle time. No single model or package can accurately estimate the required fleet size because the fleet operating parameters are characteristically random and dynamic. In order to improve confidence in sizing the fleet for a mining project, at least two estimation models should be used. This paper demonstrates that the Machine Repair Model can be modified and used as a model for estimating truck fleet size in an open pit shovel-truck system. The modified Machine Repair Model is first applied to a virtual open pit mine case study. The results compare favourably to output from other estimation models using the same input parameters for the virtual mine. The modified Machine Repair Model is further applied to an existing open pit coal operation, the Kwagga Section of Optimum Colliery as a case study. Again the results confirm those obtained from the virtual mine case study. It is concluded that the Machine Repair Model can be an affordable model compared to off-the-shelf generic software because it is easily modelled in Microsoft Excel, a software platform that most mines already use.

  12. Machine Vision-Based Measurement Systems for Fruit and Vegetable Quality Control in Postharvest.

    Science.gov (United States)

    Blasco, José; Munera, Sandra; Aleixos, Nuria; Cubero, Sergio; Molto, Enrique

    Individual items of any agricultural commodity are different from each other in terms of colour, shape or size. Furthermore, as they are living thing, they change their quality attributes over time, thereby making the development of accurate automatic inspection machines a challenging task. Machine vision-based systems and new optical technologies make it feasible to create non-destructive control and monitoring tools for quality assessment to ensure adequate accomplishment of food standards. Such systems are much faster than any manual non-destructive examination of fruit and vegetable quality, thus allowing the whole production to be inspected with objective and repeatable criteria. Moreover, current technology makes it possible to inspect the fruit in spectral ranges beyond the sensibility of the human eye, for instance in the ultraviolet and near-infrared regions. Machine vision-based applications require the use of multiple technologies and knowledge, ranging from those related to image acquisition (illumination, cameras, etc.) to the development of algorithms for spectral image analysis. Machine vision-based systems for inspecting fruit and vegetables are targeted towards different purposes, from in-line sorting into commercial categories to the detection of contaminants or the distribution of specific chemical compounds on the product's surface. This chapter summarises the current state of the art in these techniques, starting with systems based on colour images for the inspection of conventional colour, shape or external defects and then goes on to consider recent developments in spectral image analysis for internal quality assessment or contaminant detection.

  13. The Role of the Immune System in Metabolic Health and Disease.

    Science.gov (United States)

    Zmora, Niv; Bashiardes, Stavros; Levy, Maayan; Elinav, Eran

    2017-03-07

    In addition to the immune system's traditional roles of conferring anti-infectious and anti-neoplastic protection, it has been recently implicated in the regulation of systemic metabolic homeostasis. This cross-talk between the immune and the metabolic systems is pivotal in promoting "metabolic health" throughout the life of an organism and plays fundamental roles in its adaptation to ever-changing environmental makeups and nutritional availability. Perturbations in this intricate immune-metabolic cross-talk contribute to the tendency to develop altered metabolic states that may culminate in metabolic disorders such as malnutrition, obesity, type 2 diabetes mellitus (T2DM), and other features of the metabolic syndrome. Regulators of immune-metabolic interactions include host genetics, nutritional status, and the intestinal microbiome. In this Perspective, we highlight current understanding of immune-metabolism interactions, illustrate differences among individuals and between populations in this respect, and point toward future avenues of research possibly enabling immune harnessing as means of personalized treatment for common metabolic disorders. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Coldness production and heat revalorization: particular machines; Production de froid et revalorisation de la chaleur: machines particulieres

    Energy Technology Data Exchange (ETDEWEB)

    Feidt, M. [Universite Henri Poincare - Nancy-1, 54 - Nancy (France)

    2003-10-01

    The machines presented in this article are not the common reverse cycle machines. They use some systems based on different physical principles which have some consequences on the analysis of cycles: 1 - permanent gas machines (thermal separators, pulse gas tube, thermal-acoustic machines); 2 - phase change machines (mechanical vapor compression machines, absorption machines, ejection machines, adsorption machines); 3 - thermoelectric machines (thermoelectric effects, thermodynamic model of a thermoelectric machine). (J.S.)

  15. Machine Vision Handbook

    CERN Document Server

    2012-01-01

    The automation of visual inspection is becoming more and more important in modern industry as a consistent, reliable means of judging the quality of raw materials and manufactured goods . The Machine Vision Handbook  equips the reader with the practical details required to engineer integrated mechanical-optical-electronic-software systems. Machine vision is first set in the context of basic information on light, natural vision, colour sensing and optics. The physical apparatus required for mechanized image capture – lenses, cameras, scanners and light sources – are discussed followed by detailed treatment of various image-processing methods including an introduction to the QT image processing system. QT is unique to this book, and provides an example of a practical machine vision system along with extensive libraries of useful commands, functions and images which can be implemented by the reader. The main text of the book is completed by studies of a wide variety of applications of machine vision in insp...

  16. Design Control Systems of Human Machine Interface in the NTVS-2894 Seat Grinder Machine to Increase the Productivity

    Science.gov (United States)

    Ardi, S.; Ardyansyah, D.

    2018-02-01

    In the Manufacturing of automotive spare parts, increased sales of vehicles is resulted in increased demand for production of engine valve of the customer. To meet customer demand, we carry out improvement and overhaul of the NTVS-2894 seat grinder machine on a machining line. NTVS-2894 seat grinder machine has been decreased machine productivity, the amount of trouble, and the amount of downtime. To overcome these problems on overhaul the NTVS-2984 seat grinder machine include mechanical and programs, is to do the design and manufacture of HMI (Human Machine Interface) GP-4501T program. Because of the time prior to the overhaul, NTVS-2894 seat grinder machine does not have a backup HMI (Human Machine Interface) program. The goal of the design and manufacture in this program is to improve the achievement of production, and allows an operator to operate beside it easier to troubleshoot the NTVS-2894 seat grinder machine thereby reducing downtime on the NTVS-2894 seat grinder machine. The results after the design are HMI program successfully made it back, machine productivity increased by 34.8%, the amount of trouble, and downtime decreased 40% decrease from 3,160 minutes to 1,700 minutes. The implication of our design, it could facilitate the operator in operating machine and the technician easer to maintain and do the troubleshooting the machine problems.

  17. Electrical machines & drives

    CERN Document Server

    Hammond, P

    1985-01-01

    Containing approximately 200 problems (100 worked), the text covers a wide range of topics concerning electrical machines, placing particular emphasis upon electrical-machine drive applications. The theory is concisely reviewed and focuses on features common to all machine types. The problems are arranged in order of increasing levels of complexity and discussions of the solutions are included where appropriate to illustrate the engineering implications. This second edition includes an important new chapter on mathematical and computer simulation of machine systems and revised discussions o

  18. An expert system for vibration based diagnostics of rotating machines

    International Nuclear Information System (INIS)

    Korteniemi, A.

    1990-01-01

    Very often changes in the mechanical condition of the rotating machinery can be observed as changes in its vibration. This paper presents an expert system for vibration-based diagnosis of rotating machines by describing the architecture of the developed prototype system. The importance of modelling the problem solving knowledge as well as the domain knowledge is emphasized by presenting the knowledge in several levels

  19. Advanced man-machine system for nuclear power plants

    International Nuclear Information System (INIS)

    Masui, Takao; Naito, Norio; Kato, Kanji.

    1990-01-01

    Recent development of artificial intelligence(AI) seems to offer new possibility to strengthen the performance of the operator support system. From this point of view, a national project of Advanced Man-Machine System Development for Nuclear Power Plant (MMS-NPP) has been carried out since 1984 as 8-year project. This project aims at establishing advanced operator support functions which support operators in their knowledge-based behaviors and smoother interface with the system. This paper describes the role of MMS-NPP, the support functions and the main feature of the MMS-NPP detailed design with its focus placed on the realization methods using AI technology of the support functions for BWR and PWR plants. (author)

  20. CONTROL SYSTEM EVALUATION AND IMPLEMENTATION FOR THE ABRASIVE MACHINING PROCESS ON WOOD

    Directory of Open Access Journals (Sweden)

    Stephen Jackson

    2011-06-01

    Full Text Available Continuous process improvement and automation have proven to be powerful tools for the wood processing industries in order to obtain better final product quality and thus increase profits. Abrasive machining represents an important and relevant process in the manufacturing and processing of wood products, which also implies high cost of materials and labor; therefore, special attention to this process is necessary. The objective of this work was to evaluate and demonstrate a process control system for use in the abrasive machining of wood and wood-based products. A control system was created on LabView® to integrate the monitoring process and the actions required, depending on the abrasive machining process conditions. The system acquires information from the optical sensor to detect loading and activate the cleaning system. The system continuously monitors the condition of the abrasive belt (tool wear by using an acoustic emission sensor and alerts the operator of the status of the belt (green, yellow, and red lights indicating satisfactory, medium, and poor belt condition. The system also incorporates an additional safety device, which helps prevent permanent damage to the belt, equipment, or workpiece by alerting the operator when an excessive temperature has been reached. The process control system proved that automation permits enhancement in the consistency of the belt cleaning technique by the elimination of the human errors. Furthermore, this improvement also affects the cost by extending the life of the belt, which reduces setup time, belt cost, operation cost, as well as others.

  1. SAD-Based Stereo Vision Machine on a System-on-Programmable-Chip (SoPC)

    Science.gov (United States)

    Zhang, Xiang; Chen, Zhangwei

    2013-01-01

    This paper, proposes a novel solution for a stereo vision machine based on the System-on-Programmable-Chip (SoPC) architecture. The SOPC technology provides great convenience for accessing many hardware devices such as DDRII, SSRAM, Flash, etc., by IP reuse. The system hardware is implemented in a single FPGA chip involving a 32-bit Nios II microprocessor, which is a configurable soft IP core in charge of managing the image buffer and users' configuration data. The Sum of Absolute Differences (SAD) algorithm is used for dense disparity map computation. The circuits of the algorithmic module are modeled by the Matlab-based DSP Builder. With a set of configuration interfaces, the machine can process many different sizes of stereo pair images. The maximum image size is up to 512 K pixels. This machine is designed to focus on real time stereo vision applications. The stereo vision machine offers good performance and high efficiency in real time. Considering a hardware FPGA clock of 90 MHz, 23 frames of 640 × 480 disparity maps can be obtained in one second with 5 × 5 matching window and maximum 64 disparity pixels. PMID:23459385

  2. A Universal Reactive Machine

    DEFF Research Database (Denmark)

    Andersen, Henrik Reif; Mørk, Simon; Sørensen, Morten U.

    1997-01-01

    Turing showed the existence of a model universal for the set of Turing machines in the sense that given an encoding of any Turing machine asinput the universal Turing machine simulates it. We introduce the concept of universality for reactive systems and construct a CCS processuniversal...

  3. Practical aspects of the use of three-phase alternating current electric machines in electricity storage system

    Science.gov (United States)

    Ciucur, Violeta

    2015-02-01

    Of three-phase alternating current electric machines, it brings into question which of them is more advantageous to be used in electrical energy storage system by pumping water. The two major categories among which are given dispute are synchronous and the asynchronous machine. To consider the synchronous machine with permanent magnet configuration because it brings advantages compared with conventional synchronous machine, first by removing the necessary additional excitation winding. From the point of view of loss of the two types of machines, the optimal adjustment of the magnetic flux density is obtained to minimize the copper loss by hysteresis and eddy currents.

  4. JACOS: AI-based simulation system for man-machine system behavior in NPP

    International Nuclear Information System (INIS)

    Yoshida, Kazuo; Yokobayashi, Masao; Tanabe, Fumiya; Komiya, Akitoshi

    2001-08-01

    A prototype of a computer simulation system named JACOS (JAERI COgnitive Simulation system) has been developed at JAERI (Japan Atomic Energy Research Institute) to simulate the man-machine system behavior in which both the cognitive behavior of a human operator and the plant behavior affect each other. The objectives of this system development is to provide man-machine system analysts with detailed information on the cognitive process of an operator and the plant behavior affected by operator's actions in accidental situations of a nuclear power plant. The simulation system consists of an operator model and a plant model which are coupled dynamically. The operator model simulates an operator's cognitive behavior in accidental situations based on the decision ladder model of Rasmussen, and is implemented using the AI-techniques of the distributed cooperative inference method with the so-called blackboard architecture. Rule-based behavior is simulated using knowledge representation with If-Then type of rules. Knowledge-based behavior is simulated using knowledge representation with MFM (Multilevel Flow Modeling) and qualitative reasoning method. Cognitive characteristics of attentional narrowing, limitation of short-term memory, and knowledge recalling from long-term memory are also taken into account. The plant model of a 3-loop PWR is also developed using a best estimate thermal-hydraulic analysis code RELAP5/MOD2. This report is prepared as User's Manual for JACOS. The first chapter of this report describes both operator and plant models in detail. The second chapter includes instructive descriptions for program installation, building of a knowledge base for operator model, execution of simulation and analysis of simulation results. The examples of simulation with JACOS are shown in the third chapter. (author)

  5. Machine assembly with a new material handling mechanism in the sewing machine

    Directory of Open Access Journals (Sweden)

    Umarova Z.M.

    2017-05-01

    Full Text Available the paper presents the dynamic model of the machine assembly with a recommended mechanism for moving material and the definition of the law of rails motion under various system parameters. The author has suggested the solution implemented by the system of differential equations numerically on the PC and the system describing the motion of the machine set. Recommended values ​​of the parameters of elastic links of material transfer mechanism have been obtained. The researcher has developed the methods of kinematic and dynamic analysis of the material transfer mechanism with elastic elements of the sewing machine and has approved the parameters and development of the design.

  6. Feasibility of a real-time hand hygiene notification machine learning system in outpatient clinics.

    Science.gov (United States)

    Geilleit, R; Hen, Z Q; Chong, C Y; Loh, A P; Pang, N L; Peterson, G M; Ng, K C; Huis, A; de Korne, D F

    2018-04-09

    Various technologies have been developed to improve hand hygiene (HH) compliance in inpatient settings; however, little is known about the feasibility of machine learning technology for this purpose in outpatient clinics. To assess the effectiveness, user experiences, and costs of implementing a real-time HH notification machine learning system in outpatient clinics. In our mixed methods study, a multi-disciplinary team co-created an infrared guided sensor system to automatically notify clinicians to perform HH just before first patient contact. Notification technology effects were measured by comparing HH compliance at baseline (without notifications) with real-time auditory notifications that continued till HH was performed (intervention I) or notifications lasting 15 s (intervention II). User experiences were collected during daily briefings and semi-structured interviews. Costs of implementation of the system were calculated and compared to the current observational auditing programme. Average baseline HH performance before first patient contact was 53.8%. With real-time auditory notifications that continued till HH was performed, overall HH performance increased to 100% (P machine learning system were estimated to be 46% lower than the observational auditing programme. Machine learning technology that enables real-time HH notification provides a promising cost-effective approach to both improving and monitoring HH, and deserves further development in outpatient settings. Copyright © 2018 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

  7. The Central Nervous System and Bone Metabolism: An Evolving Story.

    Science.gov (United States)

    Dimitri, Paul; Rosen, Cliff

    2017-05-01

    Our understanding of the control of skeletal metabolism has undergone a dynamic shift in the last two decades, primarily driven by our understanding of energy metabolism. Evidence demonstrating that leptin not only influences bone cells directly, but that it also plays a pivotal role in controlling bone mass centrally, opened up an investigative process that has changed the way in which skeletal metabolism is now perceived. Other central regulators of bone metabolism have since been identified including neuropeptide Y (NPY), serotonin, endocannabinoids, cocaine- and amphetamine-regulated transcript (CART), adiponectin, melatonin and neuromedin U, controlling osteoblast and osteoclast differentiation, proliferation and function. The sympathetic nervous system was originally identified as the predominant efferent pathway mediating central signalling to control skeleton metabolism, in part regulated through circadian genes. More recent evidence points to a role of the parasympathetic nervous system in the control of skeletal metabolism either through muscarinic influence of sympathetic nerves in the brain or directly via nicotinic receptors on osteoclasts, thus providing evidence for broader autonomic skeletal regulation. Sensory innervation of bone has also received focus again widening our understanding of the complex neuronal regulation of bone mass. Whilst scientific advance in this field of bone metabolism has been rapid, progress is still required to understand how these model systems work in relation to the multiple confounders influencing skeletal metabolism, and the relative balance in these neuronal systems required for skeletal growth and development in childhood and maintaining skeletal integrity in adulthood.

  8. CONWIP card setting in a flow-shop system with a batch production machine

    Directory of Open Access Journals (Sweden)

    Marcello Braglia

    2011-01-01

    Full Text Available This paper presents an analytical technique to determine the optimum number of cards to control material release in a CONWIP system. The work focuses on the card setting problem for a flow-shop system characterised by the presence of a batch processing machine (e.g. a kiln for long heat treatment. To control production, two different static approaches are developed: the first one is used when the bottleneck coincides with the batch processing machine and the second one is proposed when the bottleneck is another machine of the flow shop. In both contexts, by means of the appropriate model, one can optimize the performance of the flow-shop by maximizing the throughput and keeping the work in process at a minimum level. Numerical examples are also included in the paper to confirm the validity of the models and to demonstrate their practical utility.

  9. Study of an absorption machine for an ammonia-water system ...

    African Journals Online (AJOL)

    This paper deals with Study of an absorption machine for an ammonia-water system decentralized trigeneration. The effects of evaporator, absorber and boiler temperature on the coefficient of performance of this cycle investigate. Simulation results show that with increasing the evaporator and absorber temperature the ...

  10. Distance based control system for machine vision-based selective spraying

    NARCIS (Netherlands)

    Steward, B.L.; Tian, L.F.; Tang, L.

    2002-01-01

    For effective operation of a selective sprayer with real-time local weed sensing, herbicides must be delivered, accurately to weed targets in the field. With a machine vision-based selective spraying system, acquiring sequential images and switching nozzles on and off at the correct locations are

  11. Towards a Tool for Computer Supported Configuring of Machine Systems

    DEFF Research Database (Denmark)

    Hansen, Claus Thorp

    1996-01-01

    An engineering designer designing a product determines not only the product's component structure, but also a set of different structures which carry product behaviour and performance and make the product suited for its life phases. Whereas the nature of the elements of a machine system is fairly...

  12. A support vector machine integrated system for the classification of operation anomalies in nuclear components and systems

    International Nuclear Information System (INIS)

    Rocco S, Claudio M.; Zio, Enrico

    2007-01-01

    A support vector machine (SVM) approach to the classification of transients in nuclear power plants is presented. SVM is a machine-learning algorithm that has been successfully used in pattern recognition for cluster analysis. In the present work, single- and multiclass SVM are combined into a hierarchical structure for distinguishing among transients in nuclear systems on the basis of measured data. An example of application of the approach is presented with respect to the classification of anomalies and malfunctions occurring in the feedwater system of a boiling water reactor. The data used in the example are provided by the HAMBO simulator of the Halden Reactor Project

  13. Model for Investigation of Operational Wind Power Plant Regimes with Doubly–Fed Asynchronous Machine in Power System

    Directory of Open Access Journals (Sweden)

    R. I. Mustafayev

    2012-01-01

    Full Text Available The paper presents methodology for mathematical modeling of power system (its part when jointly operated with wind power plants (stations that contain asynchronous doubly-fed machines used as generators. The essence and advantage of the methodology is that it allows efficiently to mate equations of doubly-fed asynchronous machines, written in the axes that rotate with the machine rotor speed with the equations of external electric power system, written in synchronously rotating axes.

  14. Metallic particles into mechanical and hydraulic systems in agricultural and construction machines

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Jair Rosas da; Silva, Deise Paula da [Instituto Agronomico de Campinas (IAC), Campinas, SP (Brazil). Centro de Engenharia Agricola; Bormio, Marcos Roberto [Universidade Estadual Paulista (UNESP), Bauru, SP (Brazil). Fac. de Engenharia

    2008-07-01

    The lubricant oil analysis are an indicator of the conditions how the lubricant is, may to allow the prevision of damages that occurred into machine due to the internal abrasion of hydraulic and mechanical components of the machines. The present study had the objective to determine the kind and quantity of the metallic particles that occurred into the lubricant oil of the mechanical and hydraulic compartments of the energy transmission systems of three kinds of machines: a tracked-tractor, a sugarcane harvester and a group of power-shovels. The metallic particles presents into these compartments were determined under laboratory tests and concerning to the following elements: iron, copper, chromium, lead, nickel, aluminum, silex, tin and molybdenum. About to the tracked-tractor, the metallic contaminators into to the oil charges surpasses the tolerate levels, considering the technical standards adopted in this evaluation. In the sugarcane harvester only a metallic element in excess was identified and, in a power-shovel group it was showed the need to correct air false entrances in the hydraulic or mechanical systems due the high presence of silex element. (author)

  15. Stability Enhancement of Multi machine AC Systems by Synchronverter HVDC control

    Directory of Open Access Journals (Sweden)

    Raouia Aouini

    2016-06-01

    Full Text Available This paper investigates the impact of the Synchronverter based HVDC control on power system stability. The study considers multi machine power systems, with realistic parameters. A specific tuning method of the parameters of the regulators is used. The proposed control scheme is based on the sensitivity of the poles of the HVDC neighbor zone to the control parameters, and next, on their placement using residues. The transient stability of the HVDC neighbor zone is a priori taken into account at the design stage. The new tuning method is evaluated in comparison with the standard vector control via simulation tests. Extensive tests are performed using Matlab/Simulink implementation of the IEEE 9 bus/3 machines test system. The results prove the superiority of the proposed control to the classic vector control. The synchronverter control allows to improve not only the local performances of the HVDC link, but also the overall transient stability of the AC zone in which the HVDC is inserted. (where

  16. Monitoring wear and corrosion in industrial machines and systems: A radiation tool

    International Nuclear Information System (INIS)

    Konstantinov, I.O.; Zatolokin, B.V.

    1994-01-01

    Industrial equipment and machines, transport systems, nuclear and conventional power plants, pipelines, and other materials is substantially influenced by degradation processes such as wear and corrosion. For safety and economic reasons, appropriately monitoring the damage could prevent dangerous accidents. When the surfaces of machine parts under investigation are not easy to reach or are concealed by overlying structures, nuclear methods have become powerful tools for examination. They include X-ray radiography, neutron radiography, and a technique known as thin layer activation (TLA)

  17. Philips high tension generator (x-ray machine) testing for baby ebm (electron beam machine) project

    International Nuclear Information System (INIS)

    Norman Awalludin; Leo Kwee Wah; Abu Bakar Mhd Ghazali

    2005-01-01

    This paper describes the test of the HT system (from X-ray machine) for usage of the mini EBM (Electron Beam Machine). It consists the procedures of the installation, the safety procedures when deals with HT, modification of the system for testing purpose and the technique/method for testing the HT system. As a result, the voltage for the HT system and the electron gun (filament) current can be measured. Based on the results, suitability of the machine for baby EBM could be confirmed. (Author)

  18. Man-machine communication based on the computerized operator support system

    International Nuclear Information System (INIS)

    Sano, Y.; Fukumoto, A.; Seki, E.; Tai, I.; Mori, N.; Tsuchida, M.; Sato, N.

    1985-01-01

    Development of a man-machine communication system in a nuclear power plant has been performed, utilizing the new communication technologies and an advanced diagnosis system. In the course of elaborating the communication concept, selection and rearrangement of communication functions in a control room were made based on the human factors engineering. Guidelines and criteria for information display system and operational equipments were also studied and evaluated. The outline of the communication concept and some evaluation test results are described. (author)

  19. Formal verification of automated teller machine systems using SPIN

    Science.gov (United States)

    Iqbal, Ikhwan Mohammad; Adzkiya, Dieky; Mukhlash, Imam

    2017-08-01

    Formal verification is a technique for ensuring the correctness of systems. This work focuses on verifying a model of the Automated Teller Machine (ATM) system against some specifications. We construct the model as a state transition diagram that is suitable for verification. The specifications are expressed as Linear Temporal Logic (LTL) formulas. We use Simple Promela Interpreter (SPIN) model checker to check whether the model satisfies the formula. This model checker accepts models written in Process Meta Language (PROMELA), and its specifications are specified in LTL formulas.

  20. A Study of Synchronous Machine Model Implementations in Matlab/Simulink Simulations for New and Renewable Energy Systems

    DEFF Research Database (Denmark)

    Chen, Zhe; Blaabjerg, Frede; Iov, Florin

    2005-01-01

    A direct phase model of synchronous machines implemented in MA TLAB/SIMULINK is presented. The effects of the machine saturation have been included. Simulation studies are performed under various conditions. It has been demonstrated that the MATLAB/SIMULINK is an effective tool to study the compl...... synchronous machine and the implemented model could be used for studies of various applications of synchronous machines including in renewable and DG generation systems....

  1. Machine vision system for automated detection of stained pistachio nuts

    Science.gov (United States)

    Pearson, Tom C.

    1995-01-01

    A machine vision system was developed to separate stained pistachio nuts, which comprise of about 5% of the California crop, from unstained nuts. The system may be used to reduce labor involved with manual grading or to remove aflatoxin contaminated product from low grade process streams. The system was tested on two different pistachio process streams: the bi- chromatic color sorter reject stream and the small nut shelling stock stream. The system had a minimum overall error rate of 14% for the bi-chromatic sorter reject stream and 15% for the small shelling stock stream.

  2. Machine Learning and Radiology

    Science.gov (United States)

    Wang, Shijun; Summers, Ronald M.

    2012-01-01

    In this paper, we give a short introduction to machine learning and survey its applications in radiology. We focused on six categories of applications in radiology: medical image segmentation, registration, computer aided detection and diagnosis, brain function or activity analysis and neurological disease diagnosis from fMR images, content-based image retrieval systems for CT or MRI images, and text analysis of radiology reports using natural language processing (NLP) and natural language understanding (NLU). This survey shows that machine learning plays a key role in many radiology applications. Machine learning identifies complex patterns automatically and helps radiologists make intelligent decisions on radiology data such as conventional radiographs, CT, MRI, and PET images and radiology reports. In many applications, the performance of machine learning-based automatic detection and diagnosis systems has shown to be comparable to that of a well-trained and experienced radiologist. Technology development in machine learning and radiology will benefit from each other in the long run. Key contributions and common characteristics of machine learning techniques in radiology are discussed. We also discuss the problem of translating machine learning applications to the radiology clinical setting, including advantages and potential barriers. PMID:22465077

  3. A Machine Learning Approach to Automated Gait Analysis for the Noldus Catwalk System.

    Science.gov (United States)

    Frohlich, Holger; Claes, Kasper; De Wolf, Catherine; Van Damme, Xavier; Michel, Anne

    2018-05-01

    Gait analysis of animal disease models can provide valuable insights into in vivo compound effects and thus help in preclinical drug development. The purpose of this paper is to establish a computational gait analysis approach for the Noldus Catwalk system, in which footprints are automatically captured and stored. We present a - to our knowledge - first machine learning based approach for the Catwalk system, which comprises a step decomposition, definition and extraction of meaningful features, multivariate step sequence alignment, feature selection, and training of different classifiers (gradient boosting machine, random forest, and elastic net). Using animal-wise leave-one-out cross validation we demonstrate that with our method we can reliable separate movement patterns of a putative Parkinson's disease animal model and several control groups. Furthermore, we show that we can predict the time point after and the type of different brain lesions and can even forecast the brain region, where the intervention was applied. We provide an in-depth analysis of the features involved into our classifiers via statistical techniques for model interpretation. A machine learning method for automated analysis of data from the Noldus Catwalk system was established. Our works shows the ability of machine learning to discriminate pharmacologically relevant animal groups based on their walking behavior in a multivariate manner. Further interesting aspects of the approach include the ability to learn from past experiments, improve with more data arriving and to make predictions for single animals in future studies.

  4. FY 1998 annual summary report on 6-axis, high-precision non-rotating machining systems (first year); 1998 nendo 6 jiku koseido heru kako system no kaihatsu seika hokokusho. Daiichinendo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    This R and D program is aimed at development of high-precision systems, based on non-rotating machining, in order to improve precision of machining of curved surfaces, e.g., mold, and members of complex shapes, e.g., those for aircraft. For non-rotating machining of curved surfaces, it is necessary to continuously control attitude and sending speed of the tool, and hence to simultaneously control 6 axes of a high-speed, high-precision tool machine. New techniques, e.g., high-precision non-rotating machining, 6-axis CAM/CAE systems and high-speed, high-precision NC systems, are being developed, in order to realize the above objectives. The total systems combining these techniques are also being developed. The 6-axis, high-precision, non-rotating tool machine will be made on a trial basis, to demonstrate its practicality. The major FY 1998 results are development of a non-rotating machining tool for deep grooves (under the theme of machining techniques), development of software for cutter path generation for 6-axis non-rotating machining to confirm its validity by the tests with a commercial machine (CAD/CAM), and modification of NC for early-stage cutting tests (NC). (NEDO)

  5. The Diamond machine protection system

    International Nuclear Information System (INIS)

    Heron, M.T.; Lay, S.; Chernousko, Y.; Hamadyk, P.; Rotolo, N.

    2012-01-01

    The Diamond Light Source Machine Protection System (MPS) manages the hazards from high power photon beams and other hazards to ensure equipment protection on the booster synchrotron and storage ring. The system has a shutdown requirement, on a beam mis-steer of under 1 msec and has to manage in excess of a thousand interlocks. This is realised using a combination of bespoke hardware and programmable logic controllers. The MPS monitors a large number of interlock signals from diagnostics instrumentation, vacuum instrumentation, photon front ends and plant monitoring subsystems. Based on logic it can then remove the source of the energy to ensure protection of equipment. Depending on requirements, interlocks are managed on a Local or a Global basis. The Global system is structured as two layers, and supports fast- and slow-response-time interlock requirements. A Global MPS module takes the interlock permits for a given interlock circuit from each of the cells of the accelerator, and, subject to all interlocks being good, produces a permit to operate the source of energy: the RF amplifier for vessel protection and the PSU for magnet protection. The Local MPS module takes fast Interlock inputs from one cell of the Storage Ring or one quadrant of the Booster. Fast interlocks are those that must drop the beam in under 400 μsec (the maximum speed of the interlock) in the event of failure. EPIC provides the user interface to the MPS system

  6. JACOS: AI-based simulation system for man-machine system behavior in NPP

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, Kazuo; Yokobayashi, Masao; Tanabe, Fumiya [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Kawase, Katsumi [CSK Corp., Tokyo (Japan); Komiya, Akitoshi [Computer Associated Laboratory, Inc., Hitachinaka, Ibaraki (Japan)

    2001-08-01

    A prototype of a computer simulation system named JACOS (JAERI COgnitive Simulation system) has been developed at JAERI (Japan Atomic Energy Research Institute) to simulate the man-machine system behavior in which both the cognitive behavior of a human operator and the plant behavior affect each other. The objectives of this system development is to provide man-machine system analysts with detailed information on the cognitive process of an operator and the plant behavior affected by operator's actions in accidental situations of a nuclear power plant. The simulation system consists of an operator model and a plant model which are coupled dynamically. The operator model simulates an operator's cognitive behavior in accidental situations based on the decision ladder model of Rasmussen, and is implemented using the AI-techniques of the distributed cooperative inference method with the so-called blackboard architecture. Rule-based behavior is simulated using knowledge representation with If-Then type of rules. Knowledge-based behavior is simulated using knowledge representation with MFM (Multilevel Flow Modeling) and qualitative reasoning method. Cognitive characteristics of attentional narrowing, limitation of short-term memory, and knowledge recalling from long-term memory are also taken into account. The plant model of a 3-loop PWR is also developed using a best estimate thermal-hydraulic analysis code RELAP5/MOD2. This report is prepared as User's Manual for JACOS. The first chapter of this report describes both operator and plant models in detail. The second chapter includes instructive descriptions for program installation, building of a knowledge base for operator model, execution of simulation and analysis of simulation results. The examples of simulation with JACOS are shown in the third chapter. (author)

  7. Retention system and method for the blades of a rotary machine

    Science.gov (United States)

    Pedersen, Poul D.; Glynn, Christopher C.; Walker, Roger C.

    2002-01-01

    A retention system and method for the blades of a rotary machine for preventing forward or aft axial movement of the rotor blades includes a circumferential hub slot formed about a circumference of the machine hub. The rotor blades have machined therein a blade retention slot which is aligned with the circumferential hub slot when the blades are received in correspondingly shaped openings in the hub. At least one ring segment is secured in the blade retention slots and the circumferential hub slot to retain the blades from axial movement. A key assembly is used to secure the ring segments in the aligned slots via a hook portion receiving the ring segments and a threaded portion that is driven radially outwardly by a nut. A cap may be provided to provide a redundant back-up load path for the centrifugal loads on the key. Alternatively, the key assembly may be formed in the blade dovetail.

  8. A new workstation based man/machine interface system for the JT-60 Upgrade

    International Nuclear Information System (INIS)

    Yonekawa, I.; Shimono, M.; Totsuka, T.; Yamagishi, K.

    1992-01-01

    Development of a new man/machine interface system was stimulated by the requirements of making the JT-60 operator interface more 'friendly' on the basis of the past five-year operational experience. Eleven Sun/3 workstations and their supervisory mini-computer HIDIC V90/45 are connected through the standard network; Ethernet. The network is also connected to the existing 'ZENKEI' mini-computer system through the shared memory on the HIDIC V90/45 mini-computer. Improved software, such as automatic setting of the discharge conditions, consistency check among the related parameters and easy operation for discharge result data display, offered the 'user-friendly' environments. This new man/machine interface system leads to the efficient operation of the JT-60. (author)

  9. Preliminary Test of Upgraded Conventional Milling Machine into PC Based CNC Milling Machine

    International Nuclear Information System (INIS)

    Abdul Hafid

    2008-01-01

    CNC (Computerized Numerical Control) milling machine yields a challenge to make an innovation in the field of machining. With an action job is machining quality equivalent to CNC milling machine, the conventional milling machine ability was improved to be based on PC CNC milling machine. Mechanically and instrumentally change. As a control replacing was conducted by servo drive and proximity were used. Computer programme was constructed to give instruction into milling machine. The program structure of consists GUI model and ladder diagram. Program was put on programming systems called RTX software. The result of up-grade is computer programming and CNC instruction job. The result was beginning step and it will be continued in next time. With upgrading ability milling machine becomes user can be done safe and optimal from accident risk. By improving performance of milling machine, the user will be more working optimal and safely against accident risk. (author)

  10. Simplify and Accelerate Earth Science Data Preparation to Systemize Machine Learning

    Science.gov (United States)

    Kuo, K. S.; Rilee, M. L.; Oloso, A.

    2017-12-01

    Data preparation is the most laborious and time-consuming part of machine learning. The effort required is usually more than linearly proportional to the varieties of data used. From a system science viewpoint, useful machine learning in Earth Science likely involves diverse datasets. Thus, simplifying data preparation to ease the systemization of machine learning in Earth Science is of immense value. The technologies we have developed and applied to an array database, SciDB, are explicitly designed for the purpose, including the innovative SpatioTemporal Adaptive-Resolution Encoding (STARE), a remapping tool suite, and an efficient implementation of connected component labeling (CCL). STARE serves as a universal Earth data representation that homogenizes data varieties and facilitates spatiotemporal data placement as well as alignment, to maximize query performance on massively parallel, distributed computing resources for a major class of analysis. Moreover, it converts spatiotemporal set operations into fast and efficient integer interval operations, supporting in turn moving-object analysis. Integrative analysis requires more than overlapping spatiotemporal sets. For example, meaningful comparison of temperature fields obtained with different means and resolutions requires their transformation to the same grid. Therefore, remapping has been implemented to enable integrative analysis. Finally, Earth Science investigations are generally studies of phenomena, e.g. tropical cyclone, atmospheric river, and blizzard, through their associated events, like hurricanes Katrina and Sandy. Unfortunately, except for a few high-impact phenomena, comprehensive episodic records are lacking. Consequently, we have implemented an efficient CCL tracking algorithm, enabling event-based investigations within climate data records beyond mere event presence. In summary, we have implemented the core unifying capabilities on a Big Data technology to enable systematic machine learning in

  11. Effects of activation of endocannabinoid system on myocardial metabolism

    Directory of Open Access Journals (Sweden)

    Agnieszka Polak

    2016-05-01

    Full Text Available Endocannabinoids exert their effect on the regulation of energy homeostasis via activation of specific receptors. They control food intake, secretion of insulin, lipids and glucose metabolism, lipid storage. Long chain fatty acids are the main myocardial energy substrate. However, the heart exerts enormous metabolic flexibility emphasized by its ability to utilzation not only fatty acids, but also glucose, lactate and ketone bodies. Endocannabinoids can directly act on the cardiomyocytes through the CB1 and CB2 receptors present in cardiomyocytes. It appears that direct activation of CB1 receptors promotes increased lipogenesis, pericardial steatosis and bioelectrical dysfunction of the heart. In contrast, stimulation of CB2 receptors exhibits cardioprotective properties, helping to maintain appropriate amount of ATP in cardiomyocytes. Furthermore, the effects of endocannabinoids at both the central nervous system and peripheral tissues, such as liver, pancreas, or adipose tissue, resulting indirectly in plasma availability of energy substrates and affects myocardial metabolism. To date, there is little evidence that describes effects of activation of the endocannabinoid system in the cardiovascular system under physiological conditions. In the present paper the impact of metabolic diseases, i. e. obesity and diabetes, as well as the cardiovascular diseases - hypertension, myocardial ischemia and myocardial infarction on the deregulation of the endocannabinoid system and its effect on the metabolism are described.

  12. Comparison of Models Needed for Conceptual Design of Man-Machine Systems in Different Application Domains

    DEFF Research Database (Denmark)

    Rasmussen, Jens

    1986-01-01

    and subjective preferences. For design of man-machine systems in process control, a framework has been developed in terms of separate representation of the problem domain, the decision task, and the information processing strategies required. The author analyzes the application of this framework to a number......For systematic and computer-aided design of man-machine systems, a consistent framework is needed, i. e. , a set of models which allows the selection of system characteristics which serve the individual user not only to satisfy his goal, but also to select mental processes that match his resources...

  13. The smart aerial release machine, a universal system for applying the sterile insect technique.

    Directory of Open Access Journals (Sweden)

    Ruben Leal Mubarqui

    Full Text Available Beyond insecticides, alternative methods to control insect pests for agriculture and vectors of diseases are needed. Management strategies involving the mass-release of living control agents have been developed, including genetic control with sterile insects and biological control with parasitoids, for which aerial release of insects is often required. Aerial release in genetic control programmes often involves the use of chilled sterile insects, which can improve dispersal, survival and competitiveness of sterile males. Currently available means of aerially releasing chilled fruit flies are however insufficiently precise to ensure homogeneous distribution at low release rates and no device is available for tsetse.Here we present the smart aerial release machine, a new design by the Mubarqui Company, based on the use of vibrating conveyors. The machine is controlled through Bluetooth by a tablet with Android Operating System including a completely automatic guidance and navigation system (MaxNav software. The tablet is also connected to an online relational database facilitating the preparation of flight schedules and automatic storage of flight reports. The new machine was compared with a conveyor release machine in Mexico using two fruit flies species (Anastrepha ludens and Ceratitis capitata and we obtained better dispersal homogeneity (% of positive traps, p<0.001 for both species and better recapture rates for Anastrepha ludens (p<0.001, especially at low release densities (<1500 per ha. We also demonstrated that the machine can replace paper boxes for aerial release of tsetse in Senegal.This technology limits damages to insects and allows a large range of release rates from 10 flies/km2 for tsetse flies up to 600,000 flies/km2 for fruit flies. The potential of this machine to release other species like mosquitoes is discussed. Plans and operating of the machine are provided to allow its use worldwide.

  14. The Use of Open Source Software for Open Architecture System on CNC Milling Machine

    Directory of Open Access Journals (Sweden)

    Dalmasius Ganjar Subagio

    2012-03-01

    Full Text Available Computer numerical control (CNC milling machine system cannot be separated from the software required to follow the provisions of the Open Architecture capabilities that have portability, extend ability, interoperability, and scalability. When a prescribed period of a CNC milling machine has passed and the manufacturer decided to discontinue it, then the user will have problems for maintaining the performance of the machine. This paper aims to show that the using of open source software (OSS is the way out to maintain engine performance. With the use of OSS, users no longer depend on the software built by the manufacturer because OSS is open and can be developed independently. In this paper, USBCNC V.3.42 is used as an alternative OSS. The test result shows that the work piece is in match with the desired pattern. The test result shows that the performance of machines using OSS has similar performance with the machine using software from the manufacturer. 

  15. The ASDEX upgrade digital video processing system for real-time machine protection

    Energy Technology Data Exchange (ETDEWEB)

    Drube, Reinhard, E-mail: reinhard.drube@ipp.mpg.de [Max-Planck-Institut für Plasmaphysik, EURATOM Association, Boltzmannstr. 2, 85748 Garching (Germany); Neu, Gregor [Max-Planck-Institut für Plasmaphysik, EURATOM Association, Boltzmannstr. 2, 85748 Garching (Germany); Cole, Richard H.; Lüddecke, Klaus [Unlimited Computer Systems GmbH, Seeshaupterstr. 15, 82393 Iffeldorf (Germany); Lunt, Tilmann; Herrmann, Albrecht [Max-Planck-Institut für Plasmaphysik, EURATOM Association, Boltzmannstr. 2, 85748 Garching (Germany)

    2013-11-15

    Highlights: • We present the Real-Time Video diagnostic system of ASDEX Upgrade. • We show the implemented image processing algorithms for machine protection. • The way to achieve a robust operating multi-threading Real-Time system is described. -- Abstract: This paper describes the design, implementation, and operation of the Video Real-Time (VRT) diagnostic system of the ASDEX Upgrade plasma experiment and its integration with the ASDEX Upgrade Discharge Control System (DCS). Hot spots produced by heating systems erroneously or accidentally hitting the vessel walls, or from objects in the vessel reaching into the plasma outer border, show up as bright areas in the videos during and after the reaction. A system to prevent damage to the machine by allowing for intervention in a running discharge of the experiment was proposed and implemented. The VRT was implemented on a multi-core real-time Linux system. Up to 16 analog video channels (color and b/w) are acquired and multiple regions of interest (ROI) are processed on each video frame. Detected critical states can be used to initiate appropriate reactions – e.g. gracefully terminate the discharge. The system has been in routine operation since 2007.

  16. Base for a remote quality control system for magnetic resonance images machines

    International Nuclear Information System (INIS)

    Gonzalez Dalmau, Evelio R; Cabal Mirabal, Carlos; Noda Guerra, Manuel

    2014-01-01

    The medical images systems convert characteristic of the tissues in gray levels or color, using a physical method and a specific mathematical transformation. In Magnetic Resonance Images (MRI) these levels have a multi-parametric dependence, this a reason of their strong presence in the daily clinical practice. This technological complexity, the high costs and the importance that have these study for the patient's life, confer to the Quality Control (QC) human, technological, economic and juridical implications. Several international groups dedicated to the QC in MRI and diversity of approaches to carry out the tests of acceptance and periodic control of the quality exist. The characterization is habitually carried out, with global methods that don't allow a detailed quantitative parametric study. A novel system of quantitative control was developed based on quantitative describers by slices and temporal. This system is formed for: 1) standard methodology of acquisition of the experimental data, 2) subsystem of functions and programs developed in MatLab, 3) subsystem of graphics and reports, and 4) the expert. It is used successfully in the characterization and the periodic control of MRI machines of several magnetic fields in Cuba and in Venezuela. They were defined and established quantitative descriptors for MRI machines. The software flexibility allows carry out the QC to any machine facilitating the standardization and its use in multi-center studies. The retrospective and predictive value of the system was demonstrated. They feel the bases for the remote realization of the test

  17. Conceptual design report for a Fusion Engineering Device sector-handling machine and movable manipulator system

    International Nuclear Information System (INIS)

    Watts, K.D.; Masson, L.S.; McPherson, R.S.

    1982-10-01

    Design requirements, trade studies, design descriptions, conceptual designs, and cost estimates have been completed for the Fusion Engineering Device sector handling machine, movable manipulator system, subcomponent handling machine, and limiter blade handling machine. This information will be used by the Fusion Engineering Design Center to begin to determine the cost and magnitude of the effort required to perform remote maintenance on the Fusion Engineering Device. The designs presented are by no means optimum, and the costs estimates are rough-order-of-magnitude

  18. Virtual Machine in Automation Projects

    OpenAIRE

    Xing, Xiaoyuan

    2010-01-01

    Virtual machine, as an engineering tool, has recently been introduced into automation projects in Tetra Pak Processing System AB. The goal of this paper is to examine how to better utilize virtual machine for the automation projects. This paper designs different project scenarios using virtual machine. It analyzes installability, performance and stability of virtual machine from the test results. Technical solutions concerning virtual machine are discussed such as the conversion with physical...

  19. Design and adjustment on test bed of replacing subassembly machine control system for China experimental fast reactor

    International Nuclear Information System (INIS)

    Dong Shengguo; Ma Hongsheng; Zhao Lixia

    2008-01-01

    The present research concerns in the design and adjustment of replacing sub- assembly machine control system of China Experimental Fast Reactor. The design of replacing subassembly machine control system adopts some electric equipments, such as programmable controllers, digital DC drivers. The designed control system was adjusted on the test bed. The results indicate that the operation of the control system is steady and reliable, and designed control system can meet the needs of the design specification. (authors)

  20. From scientific instrument to industrial machine coping with architectural stress in embedded systems

    CERN Document Server

    Doornbos, Richard

    2012-01-01

    Architectural stress is the inability of a system design to respond to new market demands. It is an important yet often concealed issue in high tech systems. In From scientific instrument to industrial machine, we look at the phenomenon of architectural stress in embedded systems in the context of a transmission electron microscope system built by FEI Company. Traditionally, transmission electron microscopes are manually operated scientific instruments, but they also have enormous potential for use in industrial applications. However, this new market has quite different characteristics. There are strong demands for cost-effective analysis, accurate and precise measurements, and ease-of-use. These demands can be translated into new system qualities, e.g. reliability, predictability and high throughput, as well as new functions, e.g. automation of electron microscopic analyses, automated focusing and positioning functions. From scientific instrument to industrial machine takes a pragmatic approach to the proble...

  1. Vector control of three-phase AC machines system development in the practice

    CERN Document Server

    Quang, Nguyen Phung; Dittrich, J

    2015-01-01

    This book addresses the vector control of three-phase AC machines, in particular induction motors with squirrel-cage rotors (IM), permanent magnet synchronous motors (PMSM) and doubly-fed induction machines (DFIM), from a practical design and development perspective. The main focus is on the application of IM and PMSM in electrical drive systems, where field-orientated control has been successfully established in practice. It also discusses the use of grid-voltage oriented control of DFIMs in wind power plants. This second, enlarged edition includes new insights into flatness-based  nonlinear

  2. Effect of PID Power System Stabilizer for a Synchronous Machine in Simulink Environment

    International Nuclear Information System (INIS)

    Yi, Tan Qian; Kasilingam, Gowrishankar; Raguraman, Raman

    2013-01-01

    This paper presents the use of Proportional-Integral-Derivative (PID) Controller with power system stabilizer (PSS) in a single machine infinite bus system. A PSS is used to generate supplementary damping control signals for an excitation system in order to damp out low frequency oscillations (LFO) of an electric power system. The paper is modelled in the MATLAB Simulink Environment to analyze the performance of a synchronous machine under a wide range of operating conditions. The functional blocks of PID controller with PSS are generated and the simulation studies are conducted based on different test cases to observe the dynamic performance of the power system. Analysis in this paper reveals that the PID-PSS gives better dynamic performance as compared to that of conventional power system stabilizer and also the optimal gain settings of PID PSS obtained at normal operating condition works well to other operating condition without much deterioration of the dynamic responses.

  3. A review on progress of man-machine interface system designs for Japanese PWRs

    International Nuclear Information System (INIS)

    Yoshikawa, Hidekazu; Yamamoto, Yoshihiro; Magari, Takayuki.

    1994-01-01

    Historical development of Instrumentation and Control (I and C) system designing for the PWR plants in Kansai Electric Co. Ltd is firstly reviewed with respect to the conventional PWRs in the past, brand-new PWRs (Ohi 3/4 units) and advanced PWRs (APWR) in Japan. The major features of the APWR I and C system design are extensive application of digital computer control technology and advanced man-machine interface in order to enhance safety and reliability of total I and C system and to improve human factors in nuclear power plant operation. Comparative study of the APWR's I and C system design with the EPRI's User Requirement Definitions (URD) resulted in that the current Japanese APWR I and C system design meets generally with the EPRI URD conditions except for those items mainly set by the present national regulatory guidelines. The remaining problems in the current I and C system design are discussed which include the issues on future direction of man-machine interface development. (author)

  4. The Hooey Machine.

    Science.gov (United States)

    Scarnati, James T.; Tice, Craig J.

    1992-01-01

    Describes how students can make and use Hooey Machines to learn how mechanical energy can be transferred from one object to another within a system. The Hooey Machine is made using a pencil, eight thumbtacks, one pushpin, tape, scissors, graph paper, and a plastic lid. (PR)

  5. Machine protection system algorithm compiler and simulator

    International Nuclear Information System (INIS)

    White, G.R.; Sherwin, G.

    1993-01-01

    The Machine Protection System (MPS) component of the SLC's beam selection system, in which integrated current is continuously monitored and limited to safe levels through careful selection and feedback of the beam repetition rate, is described elsewhere in these proceedings. The novel decision making mechanism by which that system can evaluate open-quotes safe levelsclose quotes, and choose an appropriate repetition rate in real-time, is described here. The algorithm that this mechanism uses to make its decision is written in test files and expressed in states of the accelerator and its devices, one file per accelerator region. Before being used, a file is open-quotes compiledclose quotes to a binary format which can be easily processed as a forward-chaining decision tree. It is processed by distributed microcomputers local to the accelerator regions. A parent algorithm evaluates all results, and reports directly to the beam control microprocessor. Operators can test new algorithms, or changes they make to them, with an online graphical MPS simulator

  6. Analysis of the steady-state operation of vacuum systems for fusion machines

    International Nuclear Information System (INIS)

    Roose, T.R.; Hoffman, M.A.; Carlson, G.A.

    1975-01-01

    A computer code named GASBAL was written to calculate the steady-state vacuum system performance of multi-chamber mirror machines as well as rather complex conventional multichamber vacuum systems. Application of the code, with some modifications, to the quasi-steady tokamak operating period should also be possible. Basically, GASBAL analyzes free molecular gas flow in a system consisting of a central chamber (the plasma chamber) connected by conductances to an arbitrary number of one- or two-chamber peripheral tanks. Each of the peripheral tanks may have vacuum pumping capability (pumping speed), sources of cold gas, and sources of energetic atoms. The central chamber may have actual vacuum pumping capability, as well as a plasma capable of ionizing injected atoms and impinging gas molecules and ''pumping'' them to a peripheral chamber. The GASBAL code was used in the preliminary design of a large mirror machine experiment--LLL's MX

  7. An intelligent human-machine system based on an ecological interface design concept

    International Nuclear Information System (INIS)

    Naito, N.

    1995-01-01

    It seems both necessary and promising to develop an intelligent human-machine system, considering the objective of the human-machine system and the recent advance in cognitive engineering and artificial intelligence together with the ever-increasing importance of human factor issues in nuclear power plant operation and maintenance. It should support human operators in their knowledge-based behaviour and allow them to cope with unanticipated abnormal events, including recovery from erroneous human actions. A top-down design approach has been adopted based on cognitive work analysis, and (1) an ecological interface, (2) a cognitive model-based advisor and (3) a robust automatic sequence controller have been established. These functions have been integrated into an experimental control room. A validation test was carried out by the participation of experienced operators and engineers. The results showed the usefulness of this system in supporting the operator's supervisory plant control tasks. ((orig.))

  8. Tribology in machine design

    CERN Document Server

    Stolarski, Tadeusz

    1999-01-01

    ""Tribology in Machine Design is strongly recommended for machine designers, and engineers and scientists interested in tribology. It should be in the engineering library of companies producing mechanical equipment.""Applied Mechanics ReviewTribology in Machine Design explains the role of tribology in the design of machine elements. It shows how algorithms developed from the basic principles of tribology can be used in a range of practical applications within mechanical devices and systems.The computer offers today's designer the possibility of greater stringen

  9. Acquisition system for the diagnostics data from a toroidal machine

    International Nuclear Information System (INIS)

    Moulin, B.

    1976-01-01

    The data acquisition system 'ARIANE' has been conceived by the SIG (Service d'Ionique Generale), for physical measurements on the toroidal machines PETULA and WEGA, which were designed to study the H.F. heating of pulsed plasmas. These systems are constitued of electronic modules which permit them to be adapted to different kinds of measurements, either by analogue channels or by pulse counting. The programmation of these systems, are achieved, either by multiswitches accessible manually on front panels, or by a computer which performs the numerical computations [fr

  10. A New Approach to Spindle Radial Error Evaluation Using a Machine Vision System

    Directory of Open Access Journals (Sweden)

    Kavitha C.

    2017-03-01

    Full Text Available The spindle rotational accuracy is one of the important issues in a machine tool which affects the surface topography and dimensional accuracy of a workpiece. This paper presents a machine-vision-based approach to radial error measurement of a lathe spindle using a CMOS camera and a PC-based image processing system. In the present work, a precisely machined cylindrical master is mounted on the spindle as a datum surface and variations of its position are captured using the camera for evaluating runout of the spindle. The Circular Hough Transform (CHT is used to detect variations of the centre position of the master cylinder during spindle rotation at subpixel level from a sequence of images. Radial error values of the spindle are evaluated using the Fourier series analysis of the centre position of the master cylinder calculated with the least squares curve fitting technique. The experiments have been carried out on a lathe at different operating speeds and the spindle radial error estimation results are presented. The proposed method provides a simpler approach to on-machine estimation of the spindle radial error in machine tools.

  11. Machine learning and radiology.

    Science.gov (United States)

    Wang, Shijun; Summers, Ronald M

    2012-07-01

    In this paper, we give a short introduction to machine learning and survey its applications in radiology. We focused on six categories of applications in radiology: medical image segmentation, registration, computer aided detection and diagnosis, brain function or activity analysis and neurological disease diagnosis from fMR images, content-based image retrieval systems for CT or MRI images, and text analysis of radiology reports using natural language processing (NLP) and natural language understanding (NLU). This survey shows that machine learning plays a key role in many radiology applications. Machine learning identifies complex patterns automatically and helps radiologists make intelligent decisions on radiology data such as conventional radiographs, CT, MRI, and PET images and radiology reports. In many applications, the performance of machine learning-based automatic detection and diagnosis systems has shown to be comparable to that of a well-trained and experienced radiologist. Technology development in machine learning and radiology will benefit from each other in the long run. Key contributions and common characteristics of machine learning techniques in radiology are discussed. We also discuss the problem of translating machine learning applications to the radiology clinical setting, including advantages and potential barriers. Copyright © 2012. Published by Elsevier B.V.

  12. Human Machine Learning Symbiosis

    Science.gov (United States)

    Walsh, Kenneth R.; Hoque, Md Tamjidul; Williams, Kim H.

    2017-01-01

    Human Machine Learning Symbiosis is a cooperative system where both the human learner and the machine learner learn from each other to create an effective and efficient learning environment adapted to the needs of the human learner. Such a system can be used in online learning modules so that the modules adapt to each learner's learning state both…

  13. Lessons from 2011 - Machine protection

    International Nuclear Information System (INIS)

    Zerlauth, M.; Schmidt, R.; Wenninger, J.

    2012-01-01

    The present architecture of the machine protection system is being recalled and the performance of the associated systems during the 2011 run will be briefly summarized. The LHC Machine Protection and Equipment Systems have been working extremely well during the 2011 run. Ever more failures are captured before effects on the particle beams are seen (i.e. no beam losses or orbit changes are observed). An analysis of the causes of beam dumps as well as an assessment of the dependability of the machine protection systems (MPS) itself is being presented. Emphasis will be given to events that risked exposing parts of the machine to damage. Further improvements and mitigations of potential holes in the protection systems will be evaluated along with their impact on the 2012 run. The role of rMPP during the various operational phases (commissioning, intensity ramp up, MDs...) will be discussed along with a proposal for the intensity ramp up for the start of beam operation in 2012

  14. Principles of image processing in machine vision systems for the color analysis of minerals

    Science.gov (United States)

    Petukhova, Daria B.; Gorbunova, Elena V.; Chertov, Aleksandr N.; Korotaev, Valery V.

    2014-09-01

    At the moment color sorting method is one of promising methods of mineral raw materials enrichment. This method is based on registration of color differences between images of analyzed objects. As is generally known the problem with delimitation of close color tints when sorting low-contrast minerals is one of the main disadvantages of color sorting method. It is can be related with wrong choice of a color model and incomplete image processing in machine vision system for realizing color sorting algorithm. Another problem is a necessity of image processing features reconfiguration when changing the type of analyzed minerals. This is due to the fact that optical properties of mineral samples vary from one mineral deposit to another. Therefore searching for values of image processing features is non-trivial task. And this task doesn't always have an acceptable solution. In addition there are no uniform guidelines for determining criteria of mineral samples separation. It is assumed that the process of image processing features reconfiguration had to be made by machine learning. But in practice it's carried out by adjusting the operating parameters which are satisfactory for one specific enrichment task. This approach usually leads to the fact that machine vision system unable to estimate rapidly the concentration rate of analyzed mineral ore by using color sorting method. This paper presents the results of research aimed at addressing mentioned shortcomings in image processing organization for machine vision systems which are used to color sorting of mineral samples. The principles of color analysis for low-contrast minerals by using machine vision systems are also studied. In addition, a special processing algorithm for color images of mineral samples is developed. Mentioned algorithm allows you to determine automatically the criteria of mineral samples separation based on an analysis of representative mineral samples. Experimental studies of the proposed algorithm

  15. The metabolic impact of methamphetamine on the systemic metabolism of rats and potential markers of methamphetamine abuse.

    Science.gov (United States)

    Zheng, Tian; Liu, Linsheng; Shi, Jian; Yu, Xiaoyi; Xiao, Wenjing; Sun, Runbing; Zhou, Yahong; Aa, Jiye; Wang, Guangji

    2014-07-01

    Although the stimulating and psychotropic effects of methamphetamine (METH) on the nervous system are well documented, the impact of METH abuse on biological metabolism and the turnover of peripheral transmitters are poorly understood. Metabolomics has the potential to reveal the effect of METH abuse on systemic metabolism and potential markers suggesting the underlying mechanism of toxicity. In this study, male Sprague Dawley rats were intraperitoneally injected with METH at escalating doses of mg kg(-1) for 5 consecutive days and then were withdrawn for 2 days. The metabolites in the serum and urine were profiled and the systemic effects of METH on metabolic pathways were evaluated. Multivariate statistical analysis showed that METH caused distinct deviations, whereas the withdrawal of METH restored the metabolic patterns towards baseline. METH administration elevated energy metabolism, which was manifested by the distinct depletion of branched-chain amino acids, accelerated tricarboxylic-acid cycle and lipid metabolism, reduced serum glycerol-3-phosphate, and elevated serum and urinary 3-hydroxybutyrate and urinary glycerol. In addition to the increased serum levels of the excitatory amino acids glutamate and aspartate (the inhibitory neurotransmitters in the brain), a marked decline in serum alanine and glycine after METH treatment suggested the activation and decreased inhibition of the nervous system and hence elevated nervous activity. Withdrawal of METH for 2 days efficiently restored all but a few metabolites to baseline, including serum creatinine, citrate, 2-ketoglutarate, and urinary lactate. Therefore, these metabolites are potential markers of METH use, and they may be used to facilitate the diagnosis of METH abuse.

  16. Modularity Design Approach for Preventive Machine Maintenance

    Science.gov (United States)

    Ernawati, D.; Pudji, E.; Ngatilah, Y.; Handoyo, R.

    2018-01-01

    In a company, machine maintenance system will be very influential in production process activity. The company should have a scheduled engine maintenance system that does not require high costs when repairing and replacing machine parts. Modularity Design method is able to provide solutions to the engine maintenance scheduling system and can prevent fatal damage to the engine components. It can minimize the cost of repair and replacement of these machine components.The paper provides a solution to machine maintenance problems. The paper is also completed with case study of milling machines. That case studies can give us a real description about impact implementation of modularity design to prevent fatal damage to components and minimize the cost of repair and replacement of components of the machine.

  17. Migrant Student Record Transfer System (MSRTS) [machine-readable data file].

    Science.gov (United States)

    Arkansas State Dept. of Education, Little Rock. General Education Div.

    The Migrant Student Record Transfer System (MSRTS) machine-readable data file (MRDF) is a collection of education and health data on more than 750,000 migrant children in grades K-12 in the United States (except Hawaii), the District of Columbia, and the outlying territories of Puerto Rico and the Mariana and Marshall Islands. The active file…

  18. From scientific instrument to industrial machine : Coping with architectural stress in embedded systems

    NARCIS (Netherlands)

    Doornbos, R.; Loo, S. van

    2012-01-01

    Architectural stress is the inability of a system design to respond to new market demands. It is an important yet often concealed issue in high tech systems. In From scientific instrument to industrial machine, we look at the phenomenon of architectural stress in embedded systems in the context of a

  19. Design foundation of vacuum system for electron beam machine

    International Nuclear Information System (INIS)

    Darsono; Suprapto; Djasiman

    1999-01-01

    Vacuum system is a main part of electron beam Machine because (EBM) the electron can not be produced without this vacuum. Vacuum system consists of vacuum pump, connecting pipe, valve, and vacuum gauge. The design vacuum system of EBM, basis knowledge and technology of vacuum is needed. The paper describes types of vacuum pump, calculation of pipe conductance and pumping time of vacuum system then there are used as consideration of criteria to choose vacuum pump for EBM. From the result of study, it is concluded that for EBM of 500 keV/10 mA which is going to use for wood coating and with consideration of economic and technic factor it is better to use diffusion pump. (author)

  20. Clinical quality needs complex adaptive systems and machine learning.

    Science.gov (United States)

    Marsland, Stephen; Buchan, Iain

    2004-01-01

    The vast increase in clinical data has the potential to bring about large improvements in clinical quality and other aspects of healthcare delivery. However, such benefits do not come without cost. The analysis of such large datasets, particularly where the data may have to be merged from several sources and may be noisy and incomplete, is a challenging task. Furthermore, the introduction of clinical changes is a cyclical task, meaning that the processes under examination operate in an environment that is not static. We suggest that traditional methods of analysis are unsuitable for the task, and identify complexity theory and machine learning as areas that have the potential to facilitate the examination of clinical quality. By its nature the field of complex adaptive systems deals with environments that change because of the interactions that have occurred in the past. We draw parallels between health informatics and bioinformatics, which has already started to successfully use machine learning methods.

  1. Systemic Metabolic Impairment and Lung Injury Following Acrolein Inhalation

    Science.gov (United States)

    A single ozone exposure causes pulmonary injury and systemic metabolic alterations through neuronal and hypothalamus pituitary adrenal axis activation. Metabolically impaired Goto Kakizaki (GK) rats with non-obese type-2 diabetes are more sensitive to ozone induced changes than h...

  2. ISOLATED SPEECH RECOGNITION SYSTEM FOR TAMIL LANGUAGE USING STATISTICAL PATTERN MATCHING AND MACHINE LEARNING TECHNIQUES

    Directory of Open Access Journals (Sweden)

    VIMALA C.

    2015-05-01

    Full Text Available In recent years, speech technology has become a vital part of our daily lives. Various techniques have been proposed for developing Automatic Speech Recognition (ASR system and have achieved great success in many applications. Among them, Template Matching techniques like Dynamic Time Warping (DTW, Statistical Pattern Matching techniques such as Hidden Markov Model (HMM and Gaussian Mixture Models (GMM, Machine Learning techniques such as Neural Networks (NN, Support Vector Machine (SVM, and Decision Trees (DT are most popular. The main objective of this paper is to design and develop a speaker-independent isolated speech recognition system for Tamil language using the above speech recognition techniques. The background of ASR system, the steps involved in ASR, merits and demerits of the conventional and machine learning algorithms and the observations made based on the experiments are presented in this paper. For the above developed system, highest word recognition accuracy is achieved with HMM technique. It offered 100% accuracy during training process and 97.92% for testing process.

  3. Rule based systems for big data a machine learning approach

    CERN Document Server

    Liu, Han; Cocea, Mihaela

    2016-01-01

    The ideas introduced in this book explore the relationships among rule based systems, machine learning and big data. Rule based systems are seen as a special type of expert systems, which can be built by using expert knowledge or learning from real data. The book focuses on the development and evaluation of rule based systems in terms of accuracy, efficiency and interpretability. In particular, a unified framework for building rule based systems, which consists of the operations of rule generation, rule simplification and rule representation, is presented. Each of these operations is detailed using specific methods or techniques. In addition, this book also presents some ensemble learning frameworks for building ensemble rule based systems.

  4. Electric machines

    CERN Document Server

    Gross, Charles A

    2006-01-01

    BASIC ELECTROMAGNETIC CONCEPTSBasic Magnetic ConceptsMagnetically Linear Systems: Magnetic CircuitsVoltage, Current, and Magnetic Field InteractionsMagnetic Properties of MaterialsNonlinear Magnetic Circuit AnalysisPermanent MagnetsSuperconducting MagnetsThe Fundamental Translational EM MachineThe Fundamental Rotational EM MachineMultiwinding EM SystemsLeakage FluxThe Concept of Ratings in EM SystemsSummaryProblemsTRANSFORMERSThe Ideal n-Winding TransformerTransformer Ratings and Per-Unit ScalingThe Nonideal Three-Winding TransformerThe Nonideal Two-Winding TransformerTransformer Efficiency and Voltage RegulationPractical ConsiderationsThe AutotransformerOperation of Transformers in Three-Phase EnvironmentsSequence Circuit Models for Three-Phase Transformer AnalysisHarmonics in TransformersSummaryProblemsBASIC MECHANICAL CONSIDERATIONSSome General PerspectivesEfficiencyLoad Torque-Speed CharacteristicsMass Polar Moment of InertiaGearingOperating ModesTranslational SystemsA Comprehensive Example: The ElevatorP...

  5. Investigation into the accuracy of a proposed laser diode based multilateration machine tool calibration system

    International Nuclear Information System (INIS)

    Fletcher, S; Longstaff, A P; Myers, A

    2005-01-01

    Geometric and thermal calibration of CNC machine tools is required in modern machine shops with volumetric accuracy assessment becoming the standard machine tool qualification in many industries. Laser interferometry is a popular method of measuring the errors but this, and other alternatives, tend to be expensive, time consuming or both. This paper investigates the feasibility of using a laser diode based system that capitalises on the low cost nature of the diode to provide multiple laser sources for fast error measurement using multilateration. Laser diode module technology enables improved wavelength stability and spectral linewidth which are important factors for laser interferometry. With more than three laser sources, the set-up process can be greatly simplified while providing flexibility in the location of the laser sources improving the accuracy of the system

  6. Control system of mutually coupled switched reluctance motor drive of mining machines in generator mode

    Science.gov (United States)

    Ivanov, A. S.; Kalanchin, I. Yu; Pugacheva, E. E.

    2017-09-01

    One of the first electric motors, based on the use of electromagnets, was a reluctance motor in the XIX century. Due to the complexities in the implementation of control system the development of switched reluctance electric machines was repeatedly initiated only in 1960 thanks to the development of computers and power electronic devices. The main feature of these machines is the capacity to work both in engine mode and in generator mode. Thanks to a simple and reliable design in which there is no winding of the rotor, commutator, permanent magnets, a reactive gate-inductor electric drive operating in the engine mode is actively being introduced into various areas such as car industry, production of household appliances, wind power engineering, as well as responsible production processes in the oil and mining industries. However, the existing shortcomings of switched reluctance electric machines, such as nonlinear pulsations of electromagnetic moment, the presence of three or four phase supply system and sensor of rotor position prevent wide distribution of this kind of electric machines.

  7. FY1995 distributed control of man-machine cooperative multi agent systems; 1995 nendo ningen kyochogata multi agent kikai system no jiritsu seigyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    In the near future, distributed autonomous systems will be practical in many situations, e.g., interactive production systems, hazardous environments, nursing homes, and individual houses. The agents which consist of the distributed system must not give damages to human being and should be working economically. In this project man-machine cooperative multi agent systems are studied in many kind of respects, and basic design technology, basic control technique are developed by establishing fundamental theories and by constructing experimental systems. In this project theoretical and experimental studies are conducted in the following sub-projects: (1) Distributed cooperative control in multi agent type actuation systems (2) Control of non-holonomic systems (3) Man-machine Cooperative systems (4) Robot systems learning human skills (5) Robust force control of constrained systems In each sub-project cooperative nature between machine agent systems and human being, interference between artificial multi agents and environment and new function emergence in coordination of the multi agents and the environment, robust force control against for the environments, control methods for non-holonomic systems, robot systems which can mimic and learn human skills were studied. In each sub-project, some problems were hi-lighted and solutions for the problems have been given based on construction of experimental systems. (NEDO)

  8. Tissue Renin-Angiotensin Systems: A Unifying Hypothesis of Metabolic Disease

    Directory of Open Access Journals (Sweden)

    Jeppe eSkov

    2014-02-01

    Full Text Available The actions of angiotensin peptides are diverse and locally acting tissue renin-angiotensin systems (RAS are present in almost all tissues of the body. An activated RAS strongly correlates to metabolic disease (e.g. diabetes and its complications and blockers of RAS have been demonstrated to prevent diabetes in humans.Hyperglycemia, obesity, hypertension, and cortisol are well-known risk factors of metabolic disease and all stimulate tissue RAS whereas glucagon-like peptide-1, vitamin D, and aerobic exercise are inhibitors of tissue RAS and to some extent can prevent metabolic disease. Furthermore, an activated tissue RAS deteriorates the same risk factors creating a system with several positive feedback pathways. The primary effector hormone of the RAS, angiotensin II, stimulates reactive oxygen species, induces tissue damage, and can be associated to most diabetic complications. Based on these observations we hypothesize that an activated tissue RAS is the principle cause of metabolic syndrome and type 2 diabetes, and additionally is mediating the majority of the metabolic complications. The involvement of positive feedback pathways may create a self-reinforcing state and explain why metabolic disease initiate and progress. The hypothesis plausibly unify the major predictors of metabolic disease and places tissue RAS regulation in the center of metabolic control.

  9. Machinic Trajectories’: Appropriated Devices as Post-Digital Drawing Machines

    Directory of Open Access Journals (Sweden)

    Andres Wanner

    2014-12-01

    Full Text Available This article presents a series of works called Machinic Trajectories, consisting of domestic devices appropriated as mechanical drawing machines. These are contextualized within the post-digital discourse, which integrates messy analog conditions into the digital realm. The role of eliciting and examining glitches for investigating a technology is pointed out. Glitches are defined as short-lived, unpremeditated aesthetic results of a failure; they are mostly known as digital phenomena, but I argue that the concept is equally applicable to the output of mechanical machines. Three drawing machines will be presented: The Opener, The Mixer and The Ventilator. In analyzing their drawings, emergent patterns consisting of unpremeditated visual artifacts will be identified and connected to irregularities of the specific technologies. Several other artists who work with mechanical and robotic drawing machines are introduced, to situate the presented works and reflections in a larger context of practice and to investigate how glitch concepts are applicable to such mechanical systems

  10. Condition Assessment and End-of-Life Prediction System for Electric Machines and Their Loads

    Science.gov (United States)

    Parlos, Alexander G.; Toliyat, Hamid A.

    2005-01-01

    An end-of-life prediction system developed for electric machines and their loads could be used in integrated vehicle health monitoring at NASA and in other government agencies. This system will provide on-line, real-time condition assessment and end-of-life prediction of electric machines (e.g., motors, generators) and/or their loads of mechanically coupled machinery (e.g., pumps, fans, compressors, turbines, conveyor belts, magnetic levitation trains, and others). In long-duration space flight, the ability to predict the lifetime of machinery could spell the difference between mission success or failure. Therefore, the system described here may be of inestimable value to the U.S. space program. The system will provide continuous monitoring for on-line condition assessment and end-of-life prediction as opposed to the current off-line diagnoses.

  11. Game-powered machine learning.

    Science.gov (United States)

    Barrington, Luke; Turnbull, Douglas; Lanckriet, Gert

    2012-04-24

    Searching for relevant content in a massive amount of multimedia information is facilitated by accurately annotating each image, video, or song with a large number of relevant semantic keywords, or tags. We introduce game-powered machine learning, an integrated approach to annotating multimedia content that combines the effectiveness of human computation, through online games, with the scalability of machine learning. We investigate this framework for labeling music. First, a socially-oriented music annotation game called Herd It collects reliable music annotations based on the "wisdom of the crowds." Second, these annotated examples are used to train a supervised machine learning system. Third, the machine learning system actively directs the annotation games to collect new data that will most benefit future model iterations. Once trained, the system can automatically annotate a corpus of music much larger than what could be labeled using human computation alone. Automatically annotated songs can be retrieved based on their semantic relevance to text-based queries (e.g., "funky jazz with saxophone," "spooky electronica," etc.). Based on the results presented in this paper, we find that actively coupling annotation games with machine learning provides a reliable and scalable approach to making searchable massive amounts of multimedia data.

  12. Understanding and applying machine vision

    CERN Document Server

    Zeuch, Nello

    2000-01-01

    A discussion of applications of machine vision technology in the semiconductor, electronic, automotive, wood, food, pharmaceutical, printing, and container industries. It describes systems that enable projects to move forward swiftly and efficiently, and focuses on the nuances of the engineering and system integration of machine vision technology.

  13. Typologically robust statistical machine translation : Understanding and exploiting differences and similarities between languages in machine translation

    NARCIS (Netherlands)

    Daiber, J.

    2018-01-01

    Machine translation systems often incorporate modeling assumptions motivated by properties of the language pairs they initially target. When such systems are applied to language families with considerably different properties, translation quality can deteriorate. Phrase-based machine translation

  14. Development of machine vision system for PHWR fuel pellet inspection

    Energy Technology Data Exchange (ETDEWEB)

    Kamalesh Kumar, B.; Reddy, K.S.; Lakshminarayana, A.; Sastry, V.S.; Ramana Rao, A.V. [Nuclear Fuel Complex, Hyderabad, Andhra Pradesh (India); Joshi, M.; Deshpande, P.; Navathe, C.P.; Jayaraj, R.N. [Raja Ramanna Centre for Advanced Technology, Indore, Madhya Pradesh (India)

    2008-07-01

    Nuclear Fuel Complex, a constituent of Department of Atomic Energy; India is responsible for manufacturing nuclear fuel in India . Over a million Uranium-di-oxide pellets fabricated per annum need visual inspection . In order to overcome the limitations of human based visual inspection, NFC has undertaken the development of machine vision system. The development involved designing various subsystems viz. mechanical and control subsystem for handling and rotation of fuel pellets, lighting subsystem for illumination, image acquisition system, and image processing system and integration. This paper brings out details of various subsystems and results obtained from the trials conducted. (author)

  15. Correlation between use time of machine and decline curve for emerging enterprise information systems

    Science.gov (United States)

    Chang, Yao-Chung; Lai, Chin-Feng; Chuang, Chi-Cheng; Hou, Cheng-Yu

    2018-04-01

    With the progress of science and technology, more and more machines are adpot to help human life better and more convenient. When the machines have been used for a longer period of time so that the machine components are getting old, the amount of power comsumption will increase and easily cause the machine to overheat. This also causes a waste of invisible resources. If the Internet of Everything (IoE) technologies are able to be applied into the enterprise information systems for monitoring the machines use time, it can not only make energy can be effectively used, but aslo create a safer living environment. To solve the above problem, the correlation predict model is established to collect the data of power consumption converted into power eigenvalues. This study takes the power eigenvalue as the independent variable and use time as the dependent variable in order to establish the decline curve. Ultimately, the scoring and estimation modules are employed to seek the best power eigenvalue as the independent variable. To predict use time, the correlation is discussed between the use time and the decline curve to improve the entire behavioural analysis of the facilitate recognition of the use time of machines.

  16. Computerized operator support system with new man-machine interface for BWR power plants

    International Nuclear Information System (INIS)

    Monta, K.; Naito, N.; Sugawara, M.; Sato, N.; Mori, N.; Tai, I.; Fukumoto, A.; Tsuchida, M.

    1984-01-01

    Improvement of the man-machine interface of nuclear power plants is an important contribution to the further enhancement of operational safety. In addition, recent advances in computer technology seem to offer the greatest opportunity to date for achieving improvement in the man-machine interface. The development of a computerized operator support system for BWRs has been undertaken since 1980 with the support of the Japanese Government. The conceptual design of this system is based on the role of the operators. The main functions are standby system management, disturbance analysis and post-trip operational guidance. The objective of the standby system management is to monitor the standby status of the engineered safety feature during normal operation to assure its proper functioning at the onset of emergency situations. The disturbance analysis system detects disturbances in the plant in their early stages and informs the plant operators about, for example, the cause of the disturbances, the plant status and possible propagations. Consequently, operators can take corrective actions to prevent unnecessary plant shutdown. The objective of the post trip operational guide is to support operators in diagnosis and corrective action after a plant trip. Its functions are to monitor the performance of the engineered safety feature, to identify the plant status and to guide the appropriate corrective action to achieve safe plant shutdown. The information from the computerized operator support system is supplied to operators through a colour CRT operator console. The authors have evaluated the performance of various new man-machine interfacing tools and proposed a new operator console design. A prototype system has been developed and verification/validation is proceeding with a BWR plant simulator. (author)

  17. Computational Modeling of Human Metabolism and Its Application to Systems Biomedicine.

    Science.gov (United States)

    Aurich, Maike K; Thiele, Ines

    2016-01-01

    Modern high-throughput techniques offer immense opportunities to investigate whole-systems behavior, such as those underlying human diseases. However, the complexity of the data presents challenges in interpretation, and new avenues are needed to address the complexity of both diseases and data. Constraint-based modeling is one formalism applied in systems biology. It relies on a genome-scale reconstruction that captures extensive biochemical knowledge regarding an organism. The human genome-scale metabolic reconstruction is increasingly used to understand normal cellular and disease states because metabolism is an important factor in many human diseases. The application of human genome-scale reconstruction ranges from mere querying of the model as a knowledge base to studies that take advantage of the model's topology and, most notably, to functional predictions based on cell- and condition-specific metabolic models built based on omics data.An increasing number and diversity of biomedical questions are being addressed using constraint-based modeling and metabolic models. One of the most successful biomedical applications to date is cancer metabolism, but constraint-based modeling also holds great potential for inborn errors of metabolism or obesity. In addition, it offers great prospects for individualized approaches to diagnostics and the design of disease prevention and intervention strategies. Metabolic models support this endeavor by providing easy access to complex high-throughput datasets. Personalized metabolic models have been introduced. Finally, constraint-based modeling can be used to model whole-body metabolism, which will enable the elucidation of metabolic interactions between organs and disturbances of these interactions as either causes or consequence of metabolic diseases. This chapter introduces constraint-based modeling and describes some of its contributions to systems biomedicine.

  18. Advanced SLARette delivery machine

    International Nuclear Information System (INIS)

    Bodner, R.R.

    1995-01-01

    SLARette 1 equipment, comprising of a SLARette Delivery Machine, SLAR Tools, SLAR power supplies and SLAR Inspection Systems was designed, developed and manufactured to service fuel channels of CANDU 6 stations during the regular yearly station outages. The Mark 2 SLARette Delivery Machine uses a Push Tube system to provide the axial and rotary movements of the SLAR Tool. The Push Tubes are operated remotely but must be attached and removed manually. Since this operation is performed at the Reactor face, there is radiation dose involved for the workers. An Advanced SLARette Delivery Machine which incorporates a computer controlled telescoping Ram in the place of the Push Tubes has been recently designed and manufactured. Utilization of the Advanced SLARette Delivery Machine significantly reduces the amount of radiation dose picked up by the workers because the need to have workers at the face of the Reactor during the SLARette operation is greatly reduced. This paper describes the design, development and manufacturing process utilized to produce the Advanced SLARette Delivery Machine and the experience gained during the Gentilly-2 NGS Spring outage. (author)

  19. Investigation of roughing machining simulation by using visual basic programming in NX CAM system

    Science.gov (United States)

    Hafiz Mohamad, Mohamad; Nafis Osman Zahid, Muhammed

    2018-03-01

    This paper outlines a simulation study to investigate the characteristic of roughing machining simulation in 4th axis milling processes by utilizing visual basic programming in NX CAM systems. The selection and optimization of cutting orientation in rough milling operation is critical in 4th axis machining. The main purpose of roughing operation is to approximately shape the machined parts into finished form by removing the bulk of material from workpieces. In this paper, the simulations are executed by manipulating a set of different cutting orientation to generate estimated volume removed from the machine parts. The cutting orientation with high volume removal is denoted as an optimum value and chosen to execute a roughing operation. In order to run the simulation, customized software is developed to assist the routines. Operations build-up instructions in NX CAM interface are translated into programming codes via advanced tool available in the Visual Basic Studio. The codes is customized and equipped with decision making tools to run and control the simulations. It permits the integration with any independent program files to execute specific operations. This paper aims to discuss about the simulation program and identifies optimum cutting orientations for roughing processes. The output of this study will broaden up the simulation routines performed in NX CAM systems.

  20. Metabolic disorders of the vestibular system.

    Science.gov (United States)

    Rybak, L P

    1995-01-01

    This article reviews the impact of metabolic disorders on vestibular function. Diabetes mellitus is a disorder of glucose metabolism that can be associated with vestibular dysfunction. Vertigo can be alleviated by diet management in many cases. Elevated levels of blood lipids have been implicated in cochleovestibular disorders. Treatment with a lipid-lowering drug has resulted in improved auditory and vestibular function in a placebo-controlled trial. Hypothyroidism may affect different parts of the vestibular system depending on the severity and duration of thyroid deficiency. Severe congenital hypothyroidism can cause central vestibular disorders affecting the cerebellum, whereas mild hypothyroidism may result in peripheral vestibulopathy. Endogenous alterations in concentrations of estrogen and progesterone in the premenstrual syndrome or with the use of exogenous hormones such as oral contraceptives may trigger vertigo. Metabolic evaluations for unexplained vertigo should include a lipoprotein profile, with cholesterol and triglyceride levels, glucose tolerance test, and thyroid hormone measurements. Nutritional and drug therapy may be useful to reverse the vestibular dysfunction.

  1. Machine learning and complex-network for personalized and systems biomedicine

    KAUST Repository

    Cannistraci, Carlo Vittorio

    2016-01-27

    The talk will begin with an introduction on using machine learning to discover hidden information and unexpected patterns in large biomedical datasets. Then, recent results on the use of complex network theory in biomedicine and neuroscience will be discussed. In particular, metagenomics and metabolomics data, approaches for drug-target repositioning, functional/structural MR connectomes and gut-brain axis data will be presented. The conclusion will outline the novel and exciting perspectives offered by the translation of these methods from systems biology to systems medicine.

  2. A novel device for head gesture measurement system in combination with eye-controlled human machine interface

    Science.gov (United States)

    Lin, Chern-Sheng; Ho, Chien-Wa; Chang, Kai-Chieh; Hung, San-Shan; Shei, Hung-Jung; Yeh, Mau-Shiun

    2006-06-01

    This study describes the design and combination of an eye-controlled and a head-controlled human-machine interface system. This system is a highly effective human-machine interface, detecting head movement by changing positions and numbers of light sources on the head. When the users utilize the head-mounted display to browse a computer screen, the system will catch the images of the user's eyes with CCD cameras, which can also measure the angle and position of the light sources. In the eye-tracking system, the program in the computer will locate each center point of the pupils in the images, and record the information on moving traces and pupil diameters. In the head gesture measurement system, the user wears a double-source eyeglass frame, so the system catches images of the user's head by using a CCD camera in front of the user. The computer program will locate the center point of the head, transferring it to the screen coordinates, and then the user can control the cursor by head motions. We combine the eye-controlled and head-controlled human-machine interface system for the virtual reality applications.

  3. Automatic welding machine for piping

    International Nuclear Information System (INIS)

    Yoshida, Kazuhiro; Koyama, Takaichi; Iizuka, Tomio; Ito, Yoshitoshi; Takami, Katsumi.

    1978-01-01

    A remotely controlled automatic special welding machine for piping was developed. This machine is utilized for long distance pipe lines, chemical plants, thermal power generating plants and nuclear power plants effectively from the viewpoint of good quality control, reduction of labor and good controllability. The function of this welding machine is to inspect the shape and dimensions of edge preparation before welding work by the sense of touch, to detect the temperature of melt pool, inspect the bead form by the sense of touch, and check the welding state by ITV during welding work, and to grind the bead surface and inspect the weld metal by ultrasonic test automatically after welding work. The construction of this welding system, the main specification of the apparatus, the welding procedure in detail, the electrical source of this welding machine, the cooling system, the structure and handling of guide ring, the central control system and the operating characteristics are explained. The working procedure and the effect by using this welding machine, and the application to nuclear power plants and the other industrial field are outlined. The HIDIC 08 is used as the controlling computer. This welding machine is useful for welding SUS piping as well as carbon steel piping. (Nakai, Y.)

  4. System Center 2012 R2 Virtual Machine Manager cookbook

    CERN Document Server

    Cardoso, Edvaldo Alessandro

    2014-01-01

    This book is a step-by-step guide packed with recipes that cover architecture design and planning. The book is also full of deployment tips, techniques, and solutions. If you are a solutions architect, technical consultant, administrator, or any other virtualization enthusiast who needs to use Microsoft System Center Virtual Machine Manager in a real-world environment, then this is the book for you. We assume that you have previous experience with Windows 2012 R2 and Hyper-V.

  5. SYSTEMS BIOLOGY AND METABOLIC ENGINEERING OF ARTHROSPIRA CELL FACTORIES

    Directory of Open Access Journals (Sweden)

    Amornpan Klanchui

    2012-10-01

    Full Text Available Arthrospira are attractive candidates to serve as cell factories for production of many valuable compounds useful for food, feed, fuel and pharmaceutical industries. In connection with the development of sustainable bioprocessing, it is a challenge to design and develop efficient Arthrospira cell factories which can certify effective conversion from the raw materials (i.e. CO2 and sun light into desired products. With the current availability of the genome sequences and metabolic models of Arthrospira, the development of Arthrospira factories can now be accelerated by means of systems biology and the metabolic engineering approach. Here, we review recent research involving the use of Arthrospira cell factories for industrial applications, as well as the exploitation of systems biology and the metabolic engineering approach for studying Arthrospira. The current status of genomics and proteomics through the development of the genome-scale metabolic model of Arthrospira, as well as the use of mathematical modeling to simulate the phenotypes resulting from the different metabolic engineering strategies are discussed. At the end, the perspective and future direction on Arthrospira cell factories for industrial biotechnology are presented.

  6. Impact of systems biology on metabolic engineering of Saccharomyces cerevisiae

    DEFF Research Database (Denmark)

    Nielsen, Jens; Jewett, Michael Christopher

    2008-01-01

    in the industrial application of this yeast. Developments in genomics and high-throughput systems biology tools are enhancing one's ability to rapidly characterize cellular behaviour, which is valuable in the field of metabolic engineering where strain characterization is often the bottleneck in strain development...... programmes. Here, the impact of systems biology on metabolic engineering is reviewed and perspectives on the role of systems biology in the design of cell factories are given....

  7. The methodology of man-machine systems

    International Nuclear Information System (INIS)

    Hollnagel, E.

    1981-10-01

    This paper provides an elementary discussion of the problems of verification and validation in the context of the empirical evaluation of designs for man-machine systems. After a definition of the basic terms, a breakdown of the major parts of the process of evaluation is given, with the purpose of indicating where problems may occur. This is followed by a discussion of verification and validation, as two distinct concepts. Finally, some of the practical problems of ascertaining validity are discussed. The general conclusion is that rather than rely blindly on a well-established procedure or rule, one should pay attention to the meaningfulness of the aspects which are selected for observation, and the degree of systematism of the methods of observation and analysis. A qualitative approach is thus seen as complementary to a quantitative approach, rather than antithetical to it. (author)

  8. Micro machining workstation for a diode pumped Nd:YAG high brightness laser system

    NARCIS (Netherlands)

    Kleijhorst, R.A.; Offerhaus, Herman L.; Bant, P.

    1998-01-01

    A Nd:YAG micro-machining workstation that allows cutting on a scale of a few microns has been developed and operated. The system incorporates a telescope viewing system that allows control during the work and a software interface to translate AutoCad files. Some examples of the performance are

  9. A low-cost machine vision system for the recognition and sorting of small parts

    Science.gov (United States)

    Barea, Gustavo; Surgenor, Brian W.; Chauhan, Vedang; Joshi, Keyur D.

    2018-04-01

    An automated machine vision-based system for the recognition and sorting of small parts was designed, assembled and tested. The system was developed to address a need to expose engineering students to the issues of machine vision and assembly automation technology, with readily available and relatively low-cost hardware and software. This paper outlines the design of the system and presents experimental performance results. Three different styles of plastic gears, together with three different styles of defective gears, were used to test the system. A pattern matching tool was used for part classification. Nine experiments were conducted to demonstrate the effects of changing various hardware and software parameters, including: conveyor speed, gear feed rate, classification, and identification score thresholds. It was found that the system could achieve a maximum system accuracy of 95% at a feed rate of 60 parts/min, for a given set of parameter settings. Future work will be looking at the effect of lighting.

  10. Automated metabolic gas analysis systems: a review.

    Science.gov (United States)

    Macfarlane, D J

    2001-01-01

    The use of automated metabolic gas analysis systems or metabolic measurement carts (MMC) in exercise studies is common throughout the industrialised world. They have become essential tools for diagnosing many hospital patients, especially those with cardiorespiratory disease. Moreover, the measurement of maximal oxygen uptake (VO2max) is routine for many athletes in fitness laboratories and has become a defacto standard in spite of its limitations. The development of metabolic carts has also facilitated the noninvasive determination of the lactate threshold and cardiac output, respiratory gas exchange kinetics, as well as studies of outdoor activities via small portable systems that often use telemetry. Although the fundamental principles behind the measurement of oxygen uptake (VO2) and carbon dioxide production (VCO2) have not changed, the techniques used have, and indeed, some have almost turned through a full circle. Early scientists often employed a manual Douglas bag method together with separate chemical analyses, but the need for faster and more efficient techniques fuelled the development of semi- and full-automated systems by private and commercial institutions. Yet, recently some scientists are returning back to the traditional Douglas bag or Tissot-spirometer methods, or are using less complex automated systems to not only save capital costs, but also to have greater control over the measurement process. Over the last 40 years, a considerable number of automated systems have been developed, with over a dozen commercial manufacturers producing in excess of 20 different automated systems. The validity and reliability of all these different systems is not well known, with relatively few independent studies having been published in this area. For comparative studies to be possible and to facilitate greater consistency of measurements in test-retest or longitudinal studies of individuals, further knowledge about the performance characteristics of these

  11. On-machine measurement of a slow slide servo diamond-machined 3D microstructure with a curved substrate

    International Nuclear Information System (INIS)

    Zhu, Wu-Le; Yang, Shunyao; Ju, Bing-Feng; Jiang, Jiacheng; Sun, Anyu

    2015-01-01

    A scanning tunneling microscope-based multi-axis measuring system is specially developed for the on-machine measurement of three-dimensional (3D) microstructures, to address the quality control difficulty with the traditional off-line measurement process. A typical 3D microstructure of the curved compound eye was diamond-machined by the slow slide servo technique, and then the whole surface was on-machine scanned three-dimensionally based on the tip-tracking strategy by utilizing a spindle, two linear motion stages, and an additional rotary stage. The machined surface profile and its shape deviation were accurately measured on-machine. The distortion of imaged ommatidia on the curved substrate was distinctively evaluated based on the characterized points extracted from the measured surface. Furthermore, the machining errors were investigated in connection with the on-machine measured surface and its characteristic parameters. Through experiments, the proposed measurement system is demonstrated to feature versatile on-machine measurement of 3D microstructures with a curved substrate, which is highly meaningful for quality control in the fabrication field. (paper)

  12. Design of a drying system for a rollover carwash machine using CFD

    Directory of Open Access Journals (Sweden)

    Seyyed M.M. Sabet

    2016-10-01

    Full Text Available This work describes the design and development of a new drying system for a rollover carwash machine with the support of numerical tools. The drying system is composed of a pair of stationary vertical dryers and a moveable horizontal dryer that can adjust itself to the contour of a vehicle. After the definition of the dryers’ concept, their performance was assessed individually to check their internal flow pattern and to improve their airflow distribution. These issues are expected to provide feedback on redesign and geometric optimization of the dryers. After redesign of the dryers separately, the behaviour of the complete drying system was studied on actual vehicle models, representative of the shortest and tallest dimensions that can be washed with the existing carwash machine sector. The drying efficiency of the whole system was studied by calculation of shear stress distribution on various surfaces of a given vehicle. The results allowed concluding that the overall drying performance of the design system is very good and assure adequate drying on most vehicles surfaces. The results obtained from numerical studies were then validated with experimental measurements and a good agreement was found between the two. The procedure employed in this work can be applied to support the design and analysis of other mechanical drying systems.

  13. Machine Translation Effect on Communication

    DEFF Research Database (Denmark)

    Jensen, Mika Yasuoka; Bjørn, Pernille

    2011-01-01

    Intercultural collaboration facilitated by machine translation has gradually spread in various settings. Still, little is known as for the practice of machine-translation mediated communication. This paper investigates how machine translation affects intercultural communication in practice. Based...... on communication in which multilingual communication system is applied, we identify four communication types and its’ influences on stakeholders’ communication process, especially focusing on establishment and maintenance of common ground. Different from our expectation that quality of machine translation results...

  14. Man-machine supervision; Supervision homme-machine

    Energy Technology Data Exchange (ETDEWEB)

    Montmain, J. [CEA Valrho, Dir. de l' Energie Nucleaire (DEN), 30 - Marcoule (France)

    2005-05-01

    Today's complexity of systems where man is involved has led to the development of more and more sophisticated information processing systems where decision making has become more and more difficult. The operator task has moved from operation to supervision and the production tool has become indissociable from its numerical instrumentation and control system. The integration of more and more numerous and sophisticated control indicators in the control room does not necessary fulfill the expectations of the operation team. It is preferable to develop cooperative information systems which are real situation understanding aids. The stake is not the automation of operators' cognitive tasks but the supply of a reasoning help. One of the challenges of interactive information systems is the selection, organisation and dynamical display of information. The efficiency of the whole man-machine system depends on the communication interface efficiency. This article presents the principles and specificities of man-machine supervision systems: 1 - principle: operator's role in control room, operator and automation, monitoring and diagnosis, characteristics of useful models for supervision; 2 - qualitative reasoning: origin, trends, evolutions; 3 - causal reasoning: causality, causal graph representation, causal and diagnostic graph; 4 - multi-points of view reasoning: multi flow modeling method, Sagace method; 5 - approximate reasoning: the symbolic numerical interface, the multi-criteria decision; 6 - example of application: supervision in a spent-fuel reprocessing facility. (J.S.)

  15. Machine-to-machine communications architectures, technology, standards, and applications

    CERN Document Server

    Misic, Vojislav B

    2014-01-01

    With the number of machine-to-machine (M2M)-enabled devices projected to reach 20 to 50 billion by 2020, there is a critical need to understand the demands imposed by such systems. Machine-to-Machine Communications: Architectures, Technology, Standards, and Applications offers rigorous treatment of the many facets of M2M communication, including its integration with current technology.Presenting the work of a different group of international experts in each chapter, the book begins by supplying an overview of M2M technology. It considers proposed standards, cutting-edge applications, architectures, and traffic modeling and includes case studies that highlight the differences between traditional and M2M communications technology.Details a practical scheme for the forward error correction code designInvestigates the effectiveness of the IEEE 802.15.4 low data rate wireless personal area network standard for use in M2M communicationsIdentifies algorithms that will ensure functionality, performance, reliability, ...

  16. Building machine learning systems with Python

    CERN Document Server

    Coelho, Luis Pedro

    2015-01-01

    This book primarily targets Python developers who want to learn and use Python's machine learning capabilities and gain valuable insights from data to develop effective solutions for business problems.

  17. Extended functions of the database machine FREND for interactive systems

    International Nuclear Information System (INIS)

    Hikita, S.; Kawakami, S.; Sano, K.

    1984-01-01

    Well-designed visual interfaces encourage non-expert users to use relational database systems. In those systems such as office automation systems or engineering database systems, non-expert users interactively access to database from visual terminals. Some users may want to occupy database or other users may share database according to various situations. Because, those jobs need a lot of time to be completed, concurrency control must be well designed to enhance the concurrency. The extended method of concurrency control of FREND is presented in this paper. The authors assume that systems are composed of workstations, a local area network and the database machine FREND. This paper also stresses that those workstations and FREND must cooperate to complete concurrency control for interactive applications

  18. Dynamic analysis and vibration testing of CFRP drive-line system used in heavy-duty machine tool

    OpenAIRE

    Mo Yang; Lin Gui; Yefa Hu; Guoping Ding; Chunsheng Song

    2018-01-01

    Low critical rotary speed and large vibration in the metal drive-line system of heavy-duty machine tool affect the machining precision seriously. Replacing metal drive-line with the CFRP drive-line can effectively solve this problem. Based on the composite laminated theory and the transfer matrix method (TMM), this paper puts forward a modified TMM to analyze dynamic characteristics of CFRP drive-line system. With this modified TMM, the CFRP drive-line of a heavy vertical miller is analyzed. ...

  19. Simulation and Optimization of Contactless Power Transfer System for Rotary Ultrasonic Machining

    Directory of Open Access Journals (Sweden)

    Wang Xinwei

    2016-01-01

    Full Text Available In today’s rotary ultrasonic machining (RUM, the power transfer system is based on a contactless power system (rotary transformer rather than the slip ring that cannot cope with high-speed rotary of the tool. The efficiency of the rotary transformer is vital to the whole rotary ultrasonic machine. This paper focused on simulation of the rotary transformer and enhancing the efficiency of the rotary transformer by optimizing three main factors that influence its efficiency, including the gap between the two ferrite cores, the ratio of length and width of the ferrite core and the thickness of ferrite. The finite element model of rotary transformer was built on Maxwell platform. Simulation and optimization work was based on the finite element model. The optimization results compared with the initial simulation result showed an approximate 18% enhancement in terms of efficiency, from 77.69% to 95.2%.

  20. Singer CNC sewing and embroidery machine

    Directory of Open Access Journals (Sweden)

    Lokodi Zsolt

    2011-12-01

    Full Text Available This paper presents the adaptation of a classic foot pedal operated Singer sewing machine to a computerized numerical control (CNC sewing and embroidery machine. This machine is composed of a Singer sewing machine and a two-degrees-of-freedom XY stage designed specifically for this application. The whole system is controlled from a PC using adequate CNC control software.

  1. Design of an Adaptive Human-Machine System Based on Dynamical Pattern Recognition of Cognitive Task-Load.

    Science.gov (United States)

    Zhang, Jianhua; Yin, Zhong; Wang, Rubin

    2017-01-01

    This paper developed a cognitive task-load (CTL) classification algorithm and allocation strategy to sustain the optimal operator CTL levels over time in safety-critical human-machine integrated systems. An adaptive human-machine system is designed based on a non-linear dynamic CTL classifier, which maps a set of electroencephalogram (EEG) and electrocardiogram (ECG) related features to a few CTL classes. The least-squares support vector machine (LSSVM) is used as dynamic pattern classifier. A series of electrophysiological and performance data acquisition experiments were performed on seven volunteer participants under a simulated process control task environment. The participant-specific dynamic LSSVM model is constructed to classify the instantaneous CTL into five classes at each time instant. The initial feature set, comprising 56 EEG and ECG related features, is reduced to a set of 12 salient features (including 11 EEG-related features) by using the locality preserving projection (LPP) technique. An overall correct classification rate of about 80% is achieved for the 5-class CTL classification problem. Then the predicted CTL is used to adaptively allocate the number of process control tasks between operator and computer-based controller. Simulation results showed that the overall performance of the human-machine system can be improved by using the adaptive automation strategy proposed.

  2. Nonlinear decentralized robust governor control for hydroturbine-generator sets in multi-machine power systems

    Energy Technology Data Exchange (ETDEWEB)

    Qiang Lu; Yusong Sun; Yuanzhang Sun [Tsinghua University, Beijing (China). Dept. of Electrical Engineering; Felix F Wu; Yixin Ni [University of Hong Kong (China). Dept. of Electrical and Electronic Engineering; Yokoyama, Akihiko [University of Tokyo (Japan). Dept. of Electrical Engineering; Goto, Masuo; Konishi, Hiroo [Hitachi Ltd., Tokyo (Japan). Power System Div.

    2004-06-01

    A novel nonlinear decentralized robust governor control for hydroturbine-generator sets in multi-machine power systems is suggested in this paper. The nonelastic water hammer effect and disturbances are considered in the modeling. The advanced differential geometry theory, nonlinear robust control theory and the dynamic feedback method are combined to solve the problem. The nonlinear decentralized robust control law for the speed governor of hydroturbine-generators has been derived. The input signals to the proposed controller are all local measurements and independent to the system parameters. The derived control law guarantees the integrated system stability with disturbance attenuation, which is significant to the real power system application. Computer tests on an 8-machine, 36-bus power system show clearly the effectiveness of the new control strategy in transient stability enhancement and disturbance attenuation. The computer test results based on the suggested controller are compared favorably with those based on the conventional linear governor control. (author)

  3. Analysis of machining and machine tools

    CERN Document Server

    Liang, Steven Y

    2016-01-01

    This book delivers the fundamental science and mechanics of machining and machine tools by presenting systematic and quantitative knowledge in the form of process mechanics and physics. It gives readers a solid command of machining science and engineering, and familiarizes them with the geometry and functionality requirements of creating parts and components in today’s markets. The authors address traditional machining topics, such as: single and multiple point cutting processes grinding components accuracy and metrology shear stress in cutting cutting temperature and analysis chatter They also address non-traditional machining, such as: electrical discharge machining electrochemical machining laser and electron beam machining A chapter on biomedical machining is also included. This book is appropriate for advanced undergraduate and graduate mechani cal engineering students, manufacturing engineers, and researchers. Each chapter contains examples, exercises and their solutions, and homework problems that re...

  4. Operating of mobile machine units system using the model of multicomponent complex movement

    OpenAIRE

    A. Lebedev; R. Kaidalov; N. Artiomov; M. Shulyak; M. Podrigalo; D. Abramov; D. Klets

    2015-01-01

    To solve the problems of mobile machine units system operating it is proposed using complex multi-component (composite) movement physical models. Implementation of the proposed method is possible by creating of automatic operating systems of fuel supply to the engines using linear accelerometers. Some examples to illustrate the proposed method are offered.

  5. Model of large scale man-machine systems with an application to vessel traffic control

    NARCIS (Netherlands)

    Wewerinke, P.H.; van der Ent, W.I.; ten Hove, D.

    1989-01-01

    Mathematical models are discussed to deal with complex large-scale man-machine systems such as vessel (air, road) traffic and process control systems. Only interrelationships between subsystems are assumed. Each subsystem is controlled by a corresponding human operator (HO). Because of the

  6. ML-o-Scope: A Diagnostic Visualization System for Deep Machine Learning Pipelines

    Science.gov (United States)

    2014-05-16

    Huawei , Intel, Microsoft, NetApp, Pivotal, Splunk, Virdata, VMware, WANdisco and Yahoo!. ML-o-scope: a diagnostic visualization system for deep machine...Facebook, GameOnTalis, Guavus, HP, Huawei , Intel, Microsoft, NetApp, Pivotal, Splunk, Virdata, VMware, WANdisco and Yahoo!. References [1] Bruna, J., and

  7. Real-time PCR Machine System Modeling and a Systematic Approach for the Robust Design of a Real-time PCR-on-a-Chip System

    OpenAIRE

    Lee, Da-Sheng

    2010-01-01

    Chip-based DNA quantification systems are widespread, and used in many point-of-care applications. However, instruments for such applications may not be maintained or calibrated regularly. Since machine reliability is a key issue for normal operation, this study presents a system model of the real-time Polymerase Chain Reaction (PCR) machine to analyze the instrument design through numerical experiments. Based on model analysis, a systematic approach was developed to lower the variation of DN...

  8. Machine interlock and protection system based on PLC for the SSRF linac

    International Nuclear Information System (INIS)

    Chou Wenjun; Zhou Dayong; Chen Jianfeng; Shen Liren; Liu Yajuan

    2008-01-01

    This paper describes a machine interlock and protection system used for accelerators based on EPICS (Experimental physics and industrial control system). The system is composed of a front-end computer and an FM-3R logic controller PLC. The alarm signal is passed by the hardware directly, and would be deal with PLC. The reporting, recording and analyst of the event are accomplished by EPICS control software. And PLC is linked to the EPICS by Internet. (authors)

  9. MODELING AND ANALYSIS OF DYNAMICS IN BEARING SYSTEM OF DRILLING, MILLING AND BORING MACHINE WITH MONO-COLUMN

    Directory of Open Access Journals (Sweden)

    Yu. V. Vasilevich

    2015-01-01

    Full Text Available  FEM-analysis of dynamics in the bearing system of a heavy-duty machine tool has been carried out in the paper. This is a prospective variant for a large-size multi-purpose machine tool with a horizontal sliding ram. A saddle and a ram are moving vertically along a subtle mono-column. A rigid double-column is used in the existing analog machine tool. A static, modal and harmonic analysis of the bearing system with the mono-column has been made in the paper. It has been done with the help of FEM-simulation prior to fabrication of a prototype sample. Previously conducted calculations for the analog machine tool have shown good compatibility of FEM-calculation with experiments.Six common machine tool resonances have been revealed for the bearing system. Their oscillating cutting forces are actively exciting three-four resonance modes. Ranges of a flexure-torsion resonance (20–40 Hz and nose-diving resonances (70–90 Hz have been determined in the paper. The paper shows that the range of multi-wave resonances starts significantly higher from 140 Hz. These resonances are interconnected with bending oscillations of the ram and bucklings of the column walls which are matched with the oscillations. The paper demonstrates stability in resonance pattern. The torsional resonance of the column on the frequency of nearly 40 Hz is considered as the more dangerous one. Spindle rigidity goes down up to 3.8 Н/μm. It is possible to observe self-stabilization of the torsional resonance. Frequency of the torsional oscillations is practically unchangeable when there is a lifting or lowering down of the saddle and the ram. It is related to the migration of dynamical axis of torsion.Frequency-response characteristics of the bearing system have been constructed for various saddle positions on the column. Three frequency intervals that make it possible to carry out machining operation have been determined in the paper. The first interval is a static one. The

  10. Implementation of Real-Time Machining Process Control Based on Fuzzy Logic in a New STEP-NC Compatible System

    Directory of Open Access Journals (Sweden)

    Po Hu

    2016-01-01

    Full Text Available Implementing real-time machining process control at shop floor has great significance on raising the efficiency and quality of product manufacturing. A framework and implementation methods of real-time machining process control based on STEP-NC are presented in this paper. Data model compatible with ISO 14649 standard is built to transfer high-level real-time machining process control information between CAPP systems and CNC systems, in which EXPRESS language is used to define new STEP-NC entities. Methods for implementing real-time machining process control at shop floor are studied and realized on an open STEP-NC controller, which is developed using object-oriented, multithread, and shared memory technologies conjunctively. Cutting force at specific direction of machining feature in side mill is chosen to be controlled object, and a fuzzy control algorithm with self-adjusting factor is designed and embedded in the software CNC kernel of STEP-NC controller. Experiments are carried out to verify the proposed framework, STEP-NC data model, and implementation methods for real-time machining process control. The results of experiments prove that real-time machining process control tasks can be interpreted and executed correctly by the STEP-NC controller at shop floor, in which actual cutting force is kept around ideal value, whether axial cutting depth changes suddenly or continuously.

  11. Design of a New Collimation System to Prevent Interference between X-ray Machines and Radiation Portal Monitors

    International Nuclear Information System (INIS)

    Guzzardo, Tyler; Livesay, Jake

    2012-01-01

    Researchers at Oak Ridge National Laboratory (ORNL) developed a new collimation system that allows radiation portal monitors (RPMs) installed near x-ray machines to operate with a negligible false-positive alarm rate. RPMs are usually installed as far as possible from x-ray machines because false alarms are triggered by escaping x-rays; however, constraints at the installation site sometimes make it necessary that RPMs be installed near x-ray machines. Such RPMs are often plagued by high alarm rates resulting from the simultaneous operation of the RPMs and x-ray machines. Limitations on pedestrian flow, x-ray machine orientation, and RPM location often preclude a simple solution for lowering the alarm rate. Adding additional collimation to the x-ray machines to stop the x-rays at the source can reduce the alarm rate without interfering with site operations or adversely affecting the minimum detectable quantity of material (MDQ). A collimation design has been verified by measurements conducted at a RPM installation site and is applicable to all new and existing RPM installations near x-ray machines.

  12. OPERATING OF MOBILE MACHINE UNITS SYSTEM USING THE MODEL OF MULTICOMPONENT COMPLEX MOVEMENT

    Directory of Open Access Journals (Sweden)

    A. Lebedev

    2015-07-01

    Full Text Available To solve the problems of mobile machine units system operating it is proposed using complex multi-component (composite movement physical models. Implementation of the proposed method is possible by creating of automatic operating systems of fuel supply to the engines using linear accelerometers. Some examples to illustrate the proposed method are offered.

  13. Design And Construction Of Controller System And Data Acquisition Of Creep Test Machine

    International Nuclear Information System (INIS)

    Farokhi; Arhatari, B.D.; DT. SonyTj.. Histori; Sudarno; Haryanto, Mudi; Triyadi, Ari

    2001-01-01

    Design and construction of creep test machine have been done to get a higher performance of controller system and data acquisition of that machine. The Design and construction were made by adding an automatic power control circuit, an interface and computer program on PC. The interface circuit is made in a form of a card which applicable on the compatible ISA-IBM PC. The computer program is written in turbo C++. With that modification, the test results show reduction in measurement error from 80μm to 90μm. The modification gives also benefit semi-automatic of the creep test machine. It means decreasing on the operator dependence. Another advantages are to make easier on the result data reading, to show the result data on the real time or on file, to make easier on appearing of a test result curve and on the result data analysis

  14. The Groningen hypothermic liver perfusion pump : Functional evaluation of a new machine perfusion system

    NARCIS (Netherlands)

    van der Plaats, A.; Maathuis, M. H. J.; Hart, N. A. 't; Bellekom, A. A.; Hofker, H. S.; van der Houwen, E. B.; Verkerke, G. J.; Leuvenink, H. G. D.; Verdonck, P.; Ploeg, R. J.; Rakhorst, G.

    2006-01-01

    To improve preservation of donor livers, we have developed a portable hypothermic machine perfusion (HMP) system as an alternative for static cold storage. A prototype of the system was built and evaluated on functionality. Evaluation criteria included 24 h of adequate pressure controlled perfusion,

  15. MODAL ANALYSIS OF CARRIER SYSTEM FOR HEAVY HORIZONTAL MULTIFUNCTION MACHINING CENTER BY FINITE ELEMENT METHOD

    Directory of Open Access Journals (Sweden)

    Yu. V. Vasilevich

    2014-01-01

    Full Text Available The aim of the paper is to reveal and analyze resonance modes of a large-scale milling-drilling-boring machine. The machine has a movable column with vertical slot occupied by a symmetrical carriage with horizontal ram. Static rigidity of the machine is relatively low due to its large dimensions. So it is necessary to assess possible vibration activity. Virtual and operational trials of the machine have been carried out simultaneously. Modeling has been executed with the help of a finite element method (FEM. The FEM-model takes into account not only rigidity of machine structures but also flexibility of bearings, feed drive systems and guides. Modal FEM-analysis has revealed eight resonance modes that embrace the whole machine tool. They form a frequency interval from 12 to 75 Hz which is undesirable for machining. Three closely located resonances (31-37 Hz are considered as the most dangerous ones. They represent various combinations of three simple motions: vertical oscillations of a carriage, horizontal vibrations of a ram and column torsion. Reliability of FEM- estimations has been proved by in-situ vibration measurements.An effect for stabilization of resonance modes has been detected while making variations in design parameters of the machine tool. For example, a virtual replacement of cast iron for steel in machine structures practically does not have any effect on resonance frequencies. Rigidity increase in some parts (e.g. a ram has also a small effect on a resonance pattern. On the other hand, resonance stability makes it possible to avoid them while selecting a spindle rotation frequency.It is recommended to set double feed drives for all axes. A pair of vertical screws prevents a “pecking” resonance of the carriage at frequency of 54 Hz. It is necessary to foresee an operation of a main drive of such heavy machine tool in the above resonance interval with the spindle frequency of more than 75 Hz. For this purpose it is necessary

  16. Human-machine interaction in nuclear power plants

    International Nuclear Information System (INIS)

    Yoshikawa, Hidekazu

    2005-01-01

    Advanced nuclear power plants are generally large complex systems automated by computers. Whenever a rate plant emergency occurs the plant operators must cope with the emergency under severe mental stress without committing any fatal errors. Furthermore, the operators must train to improve and maintain their ability to cope with every conceivable situation, though it is almost impossible to be fully prepared for an infinite variety of situations. In view of the limited capability of operators in emergency situations, there has been a new approach to preventing the human error caused by improper human-machine interaction. The new approach has been triggered by the introduction of advanced information systems that help operators recognize and counteract plant emergencies. In this paper, the adverse effect of automation in human-machine systems is explained. The discussion then focuses on how to configure a joint human-machine system for ideal human-machine interaction. Finally, there is a new proposal on how to organize technologies that recognize the different states of such a joint human-machine system

  17. 48 CFR 908.7103 - Office machines.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Office machines. 908.7103... PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition of Special Items 908.7103 Office machines. Acquisitions of office machines by DOE offices and its authorized contractors shall be in accordance with FPMR...

  18. Multi-machine power system stabilizers design using chaotic optimization algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Shayeghi, H., E-mail: hshayeghi@gmail.co [Technical Engineering Department, University of Mohaghegh Ardabili, Ardabil (Iran, Islamic Republic of); Shayanfar, H.A. [Center of Excellence for Power System Automation and Operation, Electrical Engineering Department, Iran University of Science and Technology, Tehran (Iran, Islamic Republic of); Jalilzadeh, S.; Safari, A. [Technical Engineering Department, Zanjan University, Zanjan (Iran, Islamic Republic of)

    2010-07-15

    In this paper, a multiobjective design of the multi-machine power system stabilizers (PSSs) using chaotic optimization algorithm (COA) is proposed. Chaotic optimization algorithms, which have the features of easy implementation, short execution time and robust mechanisms of escaping from the local optimum, is a promising tool for the engineering applications. The PSSs parameters tuning problem is converted to an optimization problem which is solved by a chaotic optimization algorithm based on Lozi map. Since chaotic mapping enjoys certainty, ergodicity and the stochastic property, the proposed chaotic optimization problem introduces chaos mapping using Lozi map chaotic sequences which increases its convergence rate and resulting precision. Two different objective functions are proposed in this study for the PSSs design problem. The first objective function is the eigenvalues based comprising the damping factor, and the damping ratio of the lightly damped electro-mechanical modes, while the second is the time domain-based multi-objective function. The robustness of the proposed COA-based PSSs (COAPSS) is verified on a multi-machine power system under different operating conditions and disturbances. The results of the proposed COAPSS are demonstrated through eigenvalue analysis, nonlinear time-domain simulation and some performance indices. In addition, the potential and superiority of the proposed method over the classical approach and genetic algorithm is demonstrated.

  19. The smart aerial release machine, a universal system for applying the sterile insect technique: Manuscript Draft

    International Nuclear Information System (INIS)

    Mubarqui, Leal Ruben; Perez, Rene Cano; Klad, Roberto Angulo; Lopez, Jose L. Zavale; Parker, Andrew; Seck, Momar Talla; Sall, Baba; Bouyer, Jeremy

    2014-01-01

    Beyond insecticides, alternative methods to control insect pests for agriculture and vectors of diseases are needed. Management strategies involving the mass-release of living control agents have been developed, including genetic control with sterile insects and biological control with parasitoids, for which aerial release of insects is often required. Aerial release in genetic control programmes often involves the use of chilled sterile insects, which can improve dispersal, survival and competitiveness of sterile males. Currently available means of aerially releasing chilled fruit flies are however insufficiently precise to ensure homogeneous distribution at low release rates and no device is available for tsetse. Here we present the smart aerial release machine, a new design by the Mubarqui Company, based on the use of vibrating conveyors. The machine is controlled through Bluetooth by a tablet with Android Operating System including a completely automatic guidance and navigation system (MaxNav software). The tablet is also connected to an online relational database facilitating the preparation of flight schedules and automatic storage of flight reports. The new machine was compared with a conveyor release machine in Mexico using two fruit flies species (Anastrepha ludens and Ceratitis capitata) and we obtained better dispersal homogeneity (% of positive traps, p < 0.001) for both species and better recapture rates for Anastrepha ludens (p < 0.001), especially at low release densities (<1500 per ha). We also demonstrated that the machine can replace paper boxes for aerial release of tsetse in Senegal.This technology limits damages to insects and allows a large range of release rates from 10 flies/km"2 for tsetse flies up to 600 000 flies/km"2 for fruit flies. The potential of this machine to release other species like mosquitoes is discussed. Plans and operating of the machine are provided to allow its use worldwide.

  20. Systems Biology of Metabolism: Annual Review of Biochemistry

    DEFF Research Database (Denmark)

    Nielsen, Jens

    2017-01-01

    Metabolism is highly complex and involves thousands of different connected reactions; it is therefore necessary to use mathematical models for holistic studies. The use of mathematical models in biology is referred to as systems biology. In this review, the principles of systems biology are descr...

  1. Creativity in Machine Learning

    OpenAIRE

    Thoma, Martin

    2016-01-01

    Recent machine learning techniques can be modified to produce creative results. Those results did not exist before; it is not a trivial combination of the data which was fed into the machine learning system. The obtained results come in multiple forms: As images, as text and as audio. This paper gives a high level overview of how they are created and gives some examples. It is meant to be a summary of the current work and give people who are new to machine learning some starting points.

  2. DEVELOPMENT OF INFORMATION-MEASURING SYSTEM OF DIAGNOSTICS OF ONCOLOGICAL DISEASES WITH APPLICATION OF TECHNOLOGIES OF MACHINE TRAINING

    Directory of Open Access Journals (Sweden)

    Vsevolod Novikov

    2017-12-01

    Full Text Available The purpose of the work is to create an information and measurement system of cancer with the use of machine learning technology. In this work, the object of research is the information and measuring system for diagnosing cancer, and the subject of the study is the machine learning technology based on Microsoft Azure. They are based on methods of empirical level such as: calculations, measurements, comparisons. Experimental-theoretical level methods: experiment, analysis and modeling.

  3. Metabolic engineering of Bacillus subtilis fueled by systems biology: Recent advances and future directions.

    Science.gov (United States)

    Liu, Yanfeng; Li, Jianghua; Du, Guocheng; Chen, Jian; Liu, Long

    By combining advanced omics technology and computational modeling, systems biologists have identified and inferred thousands of regulatory events and system-wide interactions of the bacterium Bacillus subtilis, which is commonly used both in the laboratory and in industry. This dissection of the multiple layers of regulatory networks and their interactions has provided invaluable information for unraveling regulatory mechanisms and guiding metabolic engineering. In this review, we discuss recent advances in the systems biology and metabolic engineering of B. subtilis and highlight current gaps in our understanding of global metabolism and global pathway engineering in this organism. We also propose future perspectives in the systems biology of B. subtilis and suggest ways that this approach can be used to guide metabolic engineering. Specifically, although hundreds of regulatory events have been identified or inferred via systems biology approaches, systematic investigation of the functionality of these events in vivo has lagged, thereby preventing the elucidation of regulatory mechanisms and further rational pathway engineering. In metabolic engineering, ignoring the engineering of multilayer regulation hinders metabolic flux redistribution. Post-translational engineering, allosteric engineering, and dynamic pathway analyses and control will also contribute to the modulation and control of the metabolism of engineered B. subtilis, ultimately producing the desired cellular traits. We hope this review will aid metabolic engineers in making full use of available systems biology datasets and approaches for the design and perfection of microbial cell factories through global metabolism optimization. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. Intellectual Control System of Processing on CNC Machines

    Science.gov (United States)

    Nekrasov, R. Y.; Lasukov, A. A.; Starikov, A. I.; Soloviev, I. V.; Bekareva, O. V.

    2016-04-01

    Scientific and technical progress makes great demands for quality of engineering production. The priority is to ensure metalworking equipment with required dimensional accuracy during the entire period of operation at minimum manufacturing costs. In article considered the problem of increasing of accuracy of processing products on CNC. The authors offers a solution to the problem by providing compensating adjustment in the trajectory of the cutting tool and machining mode. The necessity of creation of mathematical models of processes behavior in an automated technological system operations (OATS). Based on the research, authors have proposed a generalized diagram of diagnosis and input operative correction and approximate mathematical models of individual processes of diagnosis.

  5. Machine Learning for Medical Imaging.

    Science.gov (United States)

    Erickson, Bradley J; Korfiatis, Panagiotis; Akkus, Zeynettin; Kline, Timothy L

    2017-01-01

    Machine learning is a technique for recognizing patterns that can be applied to medical images. Although it is a powerful tool that can help in rendering medical diagnoses, it can be misapplied. Machine learning typically begins with the machine learning algorithm system computing the image features that are believed to be of importance in making the prediction or diagnosis of interest. The machine learning algorithm system then identifies the best combination of these image features for classifying the image or computing some metric for the given image region. There are several methods that can be used, each with different strengths and weaknesses. There are open-source versions of most of these machine learning methods that make them easy to try and apply to images. Several metrics for measuring the performance of an algorithm exist; however, one must be aware of the possible associated pitfalls that can result in misleading metrics. More recently, deep learning has started to be used; this method has the benefit that it does not require image feature identification and calculation as a first step; rather, features are identified as part of the learning process. Machine learning has been used in medical imaging and will have a greater influence in the future. Those working in medical imaging must be aware of how machine learning works. © RSNA, 2017.

  6. Exploring cluster Monte Carlo updates with Boltzmann machines.

    Science.gov (United States)

    Wang, Lei

    2017-11-01

    Boltzmann machines are physics informed generative models with broad applications in machine learning. They model the probability distribution of an input data set with latent variables and generate new samples accordingly. Applying the Boltzmann machines back to physics, they are ideal recommender systems to accelerate the Monte Carlo simulation of physical systems due to their flexibility and effectiveness. More intriguingly, we show that the generative sampling of the Boltzmann machines can even give different cluster Monte Carlo algorithms. The latent representation of the Boltzmann machines can be designed to mediate complex interactions and identify clusters of the physical system. We demonstrate these findings with concrete examples of the classical Ising model with and without four-spin plaquette interactions. In the future, automatic searches in the algorithm space parametrized by Boltzmann machines may discover more innovative Monte Carlo updates.

  7. Exploring cluster Monte Carlo updates with Boltzmann machines

    Science.gov (United States)

    Wang, Lei

    2017-11-01

    Boltzmann machines are physics informed generative models with broad applications in machine learning. They model the probability distribution of an input data set with latent variables and generate new samples accordingly. Applying the Boltzmann machines back to physics, they are ideal recommender systems to accelerate the Monte Carlo simulation of physical systems due to their flexibility and effectiveness. More intriguingly, we show that the generative sampling of the Boltzmann machines can even give different cluster Monte Carlo algorithms. The latent representation of the Boltzmann machines can be designed to mediate complex interactions and identify clusters of the physical system. We demonstrate these findings with concrete examples of the classical Ising model with and without four-spin plaquette interactions. In the future, automatic searches in the algorithm space parametrized by Boltzmann machines may discover more innovative Monte Carlo updates.

  8. Man--machine interface issues for space nuclear power systems

    International Nuclear Information System (INIS)

    Nelson, W.R.; Haugset, K.

    1991-01-01

    The deployment of nuclear reactors in space necessitates an entirely new set of guidelines for the design of the man--machine interface (MMI) when compared to earth-based applications such as commerical nuclear power plants. Although the design objectives of earth- and space-based nuclear power systems are the same, that is, to produce electrical power, the differences in the application environments mean that the operator's role will be significantly different for space-based systems. This paper explores the issues associated with establishing the necessary MMI guidelines for space nuclear power systems. The generic human performance requirements for space-based systems are described, and the operator roles that are utilized for the operation of current and advanced earth-based reactors are briefly summarized. The development of a prototype advanced control room, the Integrated Surveillance and Control System (ISACS) at the Organization for Economic Cooperation and Development (OECD) Halden Reactor Project is introduced. Finally, preliminary ideas for the use of the ISACS system as a test bed for establishing MMI guidelines for space nuclear systems are presented

  9. GPK heading machine

    Energy Technology Data Exchange (ETDEWEB)

    Krmasek, J.; Novosad, K.

    1981-01-01

    This article evaluates performance tests of the Soviet made GPK heading machine carried out in 4 coal mines in Czechoslovakia (Ostrava-Karvina region and Kladno mines). GPK works in coal seams and rocks with compression strength of 40 to 50 MPa. Dimensions of the tunnel are height 1.8 to 3.8 m and width 2.6 to 4.7 m, tunnel gradient plus to minus 10 degrees. GPK weighs 16 t, its conical shaped cutting head equipped with RKS-1 cutting tools is driven by an electric motor with 55 kW capacity. Undercarriage of the GPK, gathering-arm loader, hydraulic system, electric system and dust supression system (water spraying or pneumatic section) are characterized. Specifications of GPK heading machines are compared with PK-3r and F8 heading machines. Reliability, number of failures, dust level, noise, productivity depending on compression strength of rocks, heading rate in coal and in rocks, energy consumption, performance in inclined tunnels, and cutting tool wear are evaluated. Tests show that GPK can be used to drive tunnels in coal with rock constituting up to 50% of the tunnel crosscut, as long as rock compression strength does not exceed 50 MPa. In rocks characterized by higher compression strength cutting tool wear sharply increases. GPK is characterized by higher productivity than that of the PK-3r heading machine. Among the weak points of the GPK are: unsatisfactory reliability and excessive wear of its elements. (4 refs.) (In Czech)

  10. A future of living machines?: International trends and prospects in biomimetic and biohybrid systems

    Science.gov (United States)

    Prescott, Tony J.; Lepora, Nathan; Vershure, Paul F. M. J.

    2014-03-01

    Research in the fields of biomimetic and biohybrid systems is developing at an accelerating rate. Biomimetics can be understood as the development of new technologies using principles abstracted from the study of biological systems, however, biomimetics can also be viewed from an alternate perspective as an important methodology for improving our understanding of the world we live in and of ourselves as biological organisms. A biohybrid entity comprises at least one artificial (engineered) component combined with a biological one. With technologies such as microscale mobile computing, prosthetics and implants, humankind is moving towards a more biohybrid future in which biomimetics helps us to engineer biocompatible technologies. This paper reviews recent progress in the development of biomimetic and biohybrid systems focusing particularly on technologies that emulate living organisms—living machines. Based on our recent bibliographic analysis [1] we examine how biomimetics is already creating life-like robots and identify some key unresolved challenges that constitute bottlenecks for the field. Drawing on our recent research in biomimetic mammalian robots, including humanoids, we review the future prospects for such machines and consider some of their likely impacts on society, including the existential risk of creating artifacts with significant autonomy that could come to match or exceed humankind in intelligence. We conclude that living machines are more likely to be a benefit than a threat but that we should also ensure that progress in biomimetics and biohybrid systems is made with broad societal consent.

  11. Managing virtual machines with Vac and Vcycle

    Science.gov (United States)

    McNab, A.; Love, P.; MacMahon, E.

    2015-12-01

    We compare the Vac and Vcycle virtual machine lifecycle managers and our experiences in providing production job execution services for ATLAS, CMS, LHCb, and the GridPP VO at sites in the UK, France and at CERN. In both the Vac and Vcycle systems, the virtual machines are created outside of the experiment's job submission and pilot framework. In the case of Vac, a daemon runs on each physical host which manages a pool of virtual machines on that host, and a peer-to-peer UDP protocol is used to achieve the desired target shares between experiments across the site. In the case of Vcycle, a daemon manages a pool of virtual machines on an Infrastructure-as-a-Service cloud system such as OpenStack, and has within itself enough information to create the types of virtual machines to achieve the desired target shares. Both systems allow unused shares for one experiment to temporarily taken up by other experiements with work to be done. The virtual machine lifecycle is managed with a minimum of information, gathered from the virtual machine creation mechanism (such as libvirt or OpenStack) and using the proposed Machine/Job Features API from WLCG. We demonstrate that the same virtual machine designs can be used to run production jobs on Vac and Vcycle/OpenStack sites for ATLAS, CMS, LHCb, and GridPP, and that these technologies allow sites to be operated in a reliable and robust way.

  12. Electric machine for hybrid motor vehicle

    Science.gov (United States)

    Hsu, John Sheungchun

    2007-09-18

    A power system for a motor vehicle having an internal combustion engine and an electric machine is disclosed. The electric machine has a stator, a permanent magnet rotor, an uncluttered rotor spaced from the permanent magnet rotor, and at least one secondary core assembly. The power system also has a gearing arrangement for coupling the internal combustion engine to wheels on the vehicle thereby providing a means for the electric machine to both power assist and brake in relation to the output of the internal combustion engine.

  13. Homopolar machine design

    International Nuclear Information System (INIS)

    Thullen, P.

    1978-01-01

    A general conceptual design for a disc-type homopolar machine is presented. This machine uses a superconducting, air-core, solenoidal field winding with a peak field of 8 T. A total energy of 500 MJ is stored in two counter-rotating disc rotors that operate at a surface speed of 200 m/s. Terminal voltages of 500 to 2000 V are obtained over the range of designs studied. Brush systems to collect 3 MA are investigated. Various brush materials are discussed to determine their usefulness in this application. Sufficient information on operating characteristics in high-power applications is only available for copper-graphite brushes. The use of sliding brushes for terminal voltage regulation is discussed. This feature cannot provide a great deal of flexibility in this particular application although it may be useful during start-up. The brush system is the most demanding feature of this design. Few systems in the million ampere range have been constructed, consequently, it is not possible to predict the behavior of this brush system with great certainty. A detailed design of the brushes should be undertaken. It is estimated that the cost of such a machine will range from 0.5 to 1.5 cents per joule

  14. A modern automatic Carriage-Trolley Position Control System for Dhruva fuelling machine

    International Nuclear Information System (INIS)

    Agrawal, Ankit; Hari Balakrishna; Narvekar, J.P.; Sanadhya, Vivek

    2014-01-01

    A fully automatic absolute encoder based position control system has been designed developed implemented and commissioned for the Dhruva Fuelling Machine A (FM/A). This supports both the coarse and fine positioning modes. Provision for fully manual positioning as a standby system has been retained. This system replaces the ageing peg counting based incremental positioner used briefly during the early period after the Dhruva FM/A was commissioned. The older system suffered from peg detection skipping problems; hence it was not being used. Only full manual positioning was being carried out. This paper describes the automatic Carriage Trolley Position Control System (CTPCS). (author)

  15. Machine learning concepts in coherent optical communication systems

    DEFF Research Database (Denmark)

    Zibar, Darko; Schäffer, Christian G.

    2014-01-01

    Powerful statistical signal processing methods, used by the machine learning community, are addressed and linked to current problems in coherent optical communication. Bayesian filtering methods are presented and applied for nonlinear dynamic state tracking. © 2014 OSA.......Powerful statistical signal processing methods, used by the machine learning community, are addressed and linked to current problems in coherent optical communication. Bayesian filtering methods are presented and applied for nonlinear dynamic state tracking. © 2014 OSA....

  16. Nutritional and metabolic diseases involving the nervous system.

    Science.gov (United States)

    Kopcha, M

    1987-03-01

    This article will discuss eight diseases that alter normal nervous system function: hypovitaminosis A, water deprivation/salt toxicity, ammonia toxicosis, hypomagnesemia, hypocalcemia, nervous ketosis, hepatoencephalopathy, and rumen metabolic acidosis.

  17. Fiscal 2000 achievement report. Research on machine tool not necessitating hydraulic system; 2000 nendo yuatsu resu kosaku kikai no kenkyu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    From the viewpoint that the manufacturing process, expendable items, and recycling should all be taken into consideration when machine tool energy consumption is the matter to discuss, it is concluded that the most important policy to follow in the effort to enhance energy conservation is to enable the tool to operate without hydraulic systems. For the realization of a general-purpose machine tool (lathe) to operate free of hydraulic systems, efforts are exerted to develop element technologies, tool rests, tail stocks, and chuck drives usable for the construction of a practical hydraulic system-free machine tool. In fiscal 2000, comprehensive evaluation of experimental machine tools continued, problems to solve for practical application were put together for the fabrication of improved units, and the improved units and an improved control method were integrated into a prototype of practical machine tools. The prototype was exhibited at Japan International Machine Tool Fair (JIMTOF) as a hydraulic system-free NC (numerically controlled) lathe Type LB300, and won a high valuation. The prototype was then tested for basic performance and for possibility of improvement, and problems to be solved before commercialization were isolated. (NEDO)

  18. An expert machine tools selection system for turning operation

    NARCIS (Netherlands)

    Tan, C.F.; Khalil, S.N.; Karjanto, J.; Wahidin, L.S.; Chen, W.; Rauterberg, G.W.M.

    2015-01-01

    The turning machining process is an important process in the manufacturing industry. It is important to select the right tool for the turning process so that the manufacturing cost will be decreased. The main objective of this research is to select the most suitable machine tools with respect to

  19. Investigating cholesterol metabolism and ageing using a systems biology approach.

    Science.gov (United States)

    Morgan, A E; Mooney, K M; Wilkinson, S J; Pickles, N A; Mc Auley, M T

    2017-08-01

    CVD accounted for 27 % of all deaths in the UK in 2014, and was responsible for 1·7 million hospital admissions in 2013/2014. This condition becomes increasingly prevalent with age, affecting 34·1 and 29·8 % of males and females over 75 years of age respectively in 2011. The dysregulation of cholesterol metabolism with age, often observed as a rise in LDL-cholesterol, has been associated with the pathogenesis of CVD. To compound this problem, it is estimated by 2050, 22 % of the world's population will be over 60 years of age, in culmination with a growing resistance and intolerance to pre-existing cholesterol regulating drugs such as statins. Therefore, it is apparent research into additional therapies for hypercholesterolaemia and CVD prevention is a growing necessity. However, it is also imperative to recognise this complex biological system cannot be studied using a reductionist approach; rather its biological uniqueness necessitates a more integrated methodology, such as that offered by systems biology. In this review, we firstly discuss cholesterol metabolism and how it is affected by diet and the ageing process. Next, we describe therapeutic strategies for hypercholesterolaemia, and finally how the systems biology paradigm can be utilised to investigate how ageing interacts with complex systems such as cholesterol metabolism. We conclude by emphasising the need for nutritionists to work in parallel with the systems biology community, to develop novel approaches to studying cholesterol metabolism and its interaction with ageing.

  20. Integrated, systems metabolic picture of acetone-butanol-ethanol fermentation by Clostridium acetobutylicum.

    Science.gov (United States)

    Liao, Chen; Seo, Seung-Oh; Celik, Venhar; Liu, Huaiwei; Kong, Wentao; Wang, Yi; Blaschek, Hans; Jin, Yong-Su; Lu, Ting

    2015-07-07

    Microbial metabolism involves complex, system-level processes implemented via the orchestration of metabolic reactions, gene regulation, and environmental cues. One canonical example of such processes is acetone-butanol-ethanol (ABE) fermentation by Clostridium acetobutylicum, during which cells convert carbon sources to organic acids that are later reassimilated to produce solvents as a strategy for cellular survival. The complexity and systems nature of the process have been largely underappreciated, rendering challenges in understanding and optimizing solvent production. Here, we present a system-level computational framework for ABE fermentation that combines metabolic reactions, gene regulation, and environmental cues. We developed the framework by decomposing the entire system into three modules, building each module separately, and then assembling them back into an integrated system. During the model construction, a bottom-up approach was used to link molecular events at the single-cell level into the events at the population level. The integrated model was able to successfully reproduce ABE fermentations of the WT C. acetobutylicum (ATCC 824), as well as its mutants, using data obtained from our own experiments and from literature. Furthermore, the model confers successful predictions of the fermentations with various network perturbations across metabolic, genetic, and environmental aspects. From foundation to applications, the framework advances our understanding of complex clostridial metabolism and physiology and also facilitates the development of systems engineering strategies for the production of advanced biofuels.

  1. Energy-efficient electrical machines by new materials. Superconductivity in large electrical machines

    International Nuclear Information System (INIS)

    Frauenhofer, Joachim; Arndt, Tabea; Grundmann, Joern

    2013-01-01

    The implementation of superconducting materials in high-power electrical machines results in significant advantages regarding efficiency, size and dynamic behavior when compared to conventional machines. The application of HTS (high-temperature superconductors) in electrical machines allows significantly higher power densities to be achieved for synchronous machines. In order to gain experience with the new technology, Siemens carried out a series of development projects. A 400 kW model motor for the verification of a concept for the new technology was followed by a 4000 kV A generator as highspeed machine - as well as a low-speed 4000 kW propeller motor with high torque. The 4000 kVA generator is still employed to carry out long-term tests and to check components. Superconducting machines have significantly lower weight and envelope dimensions compared to conventional machines, and for this reason alone, they utilize resources better. At the same time, operating losses are slashed to about half and the efficiency increases. Beyond this, they set themselves apart as a result of their special features in operation, such as high overload capability, stiff alternating load behavior and low noise. HTS machines provide significant advantages where the reduction of footprint, weight and losses or the improved dynamic behavior results in significant improvements of the overall system. Propeller motors and generators,for ships, offshore plants, in wind turbine and hydroelectric plants and in large power stations are just some examples. HTS machines can therefore play a significant role when it comes to efficiently using resources and energy as well as reducing the CO 2 emissions.

  2. Cybernics fusion of human, machine and information systems

    CERN Document Server

    Suzuki, Kenji; Hasegawa, Yasuhisa

    2014-01-01

    Cybernics plays a significant role in coping with an aging society using state-of-the-art technologies from engineering, clinical medicine and humanities. This new interdisciplinary field studies technologies that enhance, strengthen, and support physical and cognitive functions of human beings, based on the fusion of human, machine, and information systems. The design of a seamless interface for interaction between the interior and exterior of the human body is described in this book from diverse aspects such as the physical, neurophysiological, and cognitive levels. It is the first book to cover the many aspects of cybernics, allowing readers to understand the life support robotics technology for the elderly, including remote, in-home, hospital, institutional, community medical welfare, and vital-sensing systems. Serving as a valuable resource, this volume will interest not only graduate students, scientists, and engineers but also newcomers to the field of cybernics.

  3. Possibilities and expectations for improved man-machine interface in power system control

    Energy Technology Data Exchange (ETDEWEB)

    Asal, H; Burrow, R K; Lindstrom, K; Mocenigo, M; Schellstede, G; Schaffer, G; Serrani, A

    1992-05-01

    The paper describes the hardware, equipment and functions provided to operators for supervising and controlling HVAC power systems. It analyzes the main elements of the man-machine interface (MMI) with particular attention to the recent possibilities afforded by computer technology and full graphic screens. Alarm management and remote control operation are briefly described.

  4. Advanced Machining Toolpath for Low Distortion

    Science.gov (United States)

    2017-02-28

    Advanced Machining Toolpath for Low Distortion FINAL STATUS REPORT Prepared by Brian Becker R&D Technology Manager Third Wave Systems, Inc... Machining Toolpath for Low Distortion December 2016 Contract No.: W911W6-16-P-0044 2 Table of Contents 1.0 EXECUTIVE SUMMARY...2 2.1 Task 1: Collect Details of Machining Lab to Support

  5. Mini lathe machine converted to CNC

    Directory of Open Access Journals (Sweden)

    Alexandru Morar

    2012-06-01

    Full Text Available This paper presents the adaptation of a mechanical mini-lathing machine to a computerized numerical control (CNC lathing machine. This machine is composed of a ASIST mini-lathe and a two-degrees-of-freedom XZ stage designed specifically for this application. The whole system is controlled from a PC using adequate CNC control software.

  6. Throughput centered prioritization of machines in transfer lines

    Energy Technology Data Exchange (ETDEWEB)

    Pascual, R., E-mail: rpascual@ing.puc.cl [Physical Asset Management Lab, Centro de Mineria, Pontificia Universidad Catolica de Chile, Av. Vicuna Mackenna 4860, Santiago (Chile); Godoy, D. [Physical Asset Management Lab, Centro de Mineria, Pontificia Universidad Catolica de Chile, Av. Vicuna Mackenna 4860, Santiago (Chile); Louit, D.M. [Komatsu Chile S.A., Av. Americo Vespucio 0631, Quilicura, Santiago (Chile)

    2011-10-15

    In an environment of scarce resources and complex production systems, prioritizing is key to confront the challenge of managing physical assets. In the literature, there exist a number of techniques to prioritize maintenance decisions that consider safety, technical and business perspectives. However, the effect of risk mitigating elements-such as intermediate buffers in production lines-on prioritization has not yet been investigated in depth. In this line, the work proposes a user-friendly graphical technique called the system efficiency influence diagram (SEID). Asset managers may use SEID to identify machines that have a greater impact on the system throughput, and thus set prioritized maintenance policies and/or redesign of buffers capacities. The tool provides insight to the analyst as it decomposes the influence of a given machine on the system throughput as a product of two elements: (1) system influence efficiency factor and (2) machine unavailability factor. We illustrate its applicability using three case studies: a four-machine transfer line, a vehicle assembly line, and an open-pit mining conveyor system. The results confirm that the machines with greater unavailability factors are not necessarily the most important for the efficiency of the production line, as it is the case when no intermediate buffers exist. As a decision aid tool, SEID emphasizes the need to move from a maintenance vision focused on machine availability, to a systems engineering perspective. - Highlights: > We propose a graphical technique to prioritize machines in production lines. > The tool is called 'system efficiency influence diagram' (SEID). > It helps setting prioritized maintenance policies and/or redesign of buffers. > The SEID technique focuses on system efficiency and throughput. > We illustrate its applicability using three case studies.

  7. Machine rates for selected forest harvesting machines

    Science.gov (United States)

    R.W. Brinker; J. Kinard; Robert Rummer; B. Lanford

    2002-01-01

    Very little new literature has been published on the subject of machine rates and machine cost analysis since 1989 when the Alabama Agricultural Experiment Station Circular 296, Machine Rates for Selected Forest Harvesting Machines, was originally published. Many machines discussed in the original publication have undergone substantial changes in various aspects, not...

  8. OptiCentric lathe centering machine

    Science.gov (United States)

    Buß, C.; Heinisch, J.

    2013-09-01

    High precision optics depend on precisely aligned lenses. The shift and tilt of individual lenses as well as the air gap between elements require accuracies in the single micron regime. These accuracies are hard to meet with traditional assembly methods. Instead, lathe centering can be used to machine the mount with respect to the optical axis. Using a diamond turning process, all relevant errors of single mounted lenses can be corrected in one post-machining step. Building on the OptiCentric® and OptiSurf® measurement systems, Trioptics has developed their first lathe centering machines. The machine and specific design elements of the setup will be shown. For example, the machine can be used to turn optics for i-line steppers with highest precision.

  9. Efficient operation of anisotropic synchronous machines for wind energy systems

    International Nuclear Information System (INIS)

    Eldeeb, Hisham; Hackl, Christoph M.; Kullick, Julian

    2016-01-01

    This paper presents an analytical solution for the Maximum-Torque-per-Ampere (MTPA) operation of synchronous machines (SM) with anisotropy and magnetic cross-coupling for the application in wind turbine systems and airborne wind energy systems. For a given reference torque, the analytical MTPA solution provides the optimal stator current references which produce the desired torque while minimizing the stator copper losses. From an implementation point of view, the proposed analytical method is appealing in terms of its fast online computation (compared to classical numerical methods) and its efficiency enhancement of the electrical drive system. The efficiency of the analytical MTPA operation, with and without consideration of cross-coupling, is compared to the conventional method with zero direct current. (paper)

  10. Machine & electrical double control air dryer for vehicle air braking system

    Science.gov (United States)

    Zhang, Xuan; Yang, Liu; Wang, Xian Yan; Tan, Xiao Yan; Wang, Wei

    2017-09-01

    As is known to all, a vehicle air brake system, in which usually contains moisture. To solve the problem, it is common to use air dryer to dry compressed air effectively and completely remove the moisture and oil of braking system. However, the existing air dryer is not suitable for all commercial vehicles. According to the operational status of the new energy vehicles in the initial operating period, the structure design principle of the machine & electric control air dryer is expounded from the aspects of the structure and operating principle, research & development process.

  11. An overview of rotating machine systems with high-temperature bulk superconductors

    Science.gov (United States)

    Zhou, Difan; Izumi, Mitsuru; Miki, Motohiro; Felder, Brice; Ida, Tetsuya; Kitano, Masahiro

    2012-10-01

    The paper contains a review of recent advancements in rotating machines with bulk high-temperature superconductors (HTS). The high critical current density of bulk HTS enables us to design rotating machines with a compact configuration in a practical scheme. The development of an axial-gap-type trapped flux synchronous rotating machine together with the systematic research works at the Tokyo University of Marine Science and Technology since 2001 are briefly introduced. Developments in bulk HTS rotating machines in other research groups are also summarized. The key issues of bulk HTS machines, including material progress of bulk HTS, in situ magnetization, and cooling together with AC loss at low-temperature operation are discussed.

  12. Machine Learning Algorithms For Predicting the Instability Timescales of Compact Planetary Systems

    Science.gov (United States)

    Tamayo, Daniel; Ali-Dib, Mohamad; Cloutier, Ryan; Huang, Chelsea; Van Laerhoven, Christa L.; Leblanc, Rejean; Menou, Kristen; Murray, Norman; Obertas, Alysa; Paradise, Adiv; Petrovich, Cristobal; Rachkov, Aleksandar; Rein, Hanno; Silburt, Ari; Tacik, Nick; Valencia, Diana

    2016-10-01

    The Kepler mission has uncovered hundreds of compact multi-planet systems. The dynamical pathways to instability in these compact systems and their associated timescales are not well understood theoretically. However, long-term stability is often used as a constraint to narrow down the space of orbital solutions from the transit data. This requires a large suite of N-body integrations that can each take several weeks to complete. This computational bottleneck is therefore an important limitation in our ability to characterize compact multi-planet systems.From suites of numerical simulations, previous studies have fit simple scaling relations between the instability timescale and various system parameters. However, the numerically simulated systems can deviate strongly from these empirical fits.We present a new approach to the problem using machine learning algorithms that have enjoyed success across a broad range of high-dimensional industry applications. In particular, we have generated large training sets of direct N-body integrations of synthetic compact planetary systems to train several regression models (support vector machine, gradient boost) that predict the instability timescale. We find that ensembling these models predicts the instability timescale of planetary systems better than previous approaches using the simple scaling relations mentioned above.Finally, we will discuss how these models provide a powerful tool for not only understanding the current Kepler multi-planet sample, but also for characterizing and shaping the radial-velocity follow-up strategies of multi-planet systems from the upcoming Transiting Exoplanet Survey Satellite (TESS) mission, given its shorter observation baselines.

  13. IDOCS: intelligent distributed ontology consensus system--the use of machine learning in retinal drusen phenotyping.

    Science.gov (United States)

    Thomas, George; Grassi, Michael A; Lee, John R; Edwards, Albert O; Gorin, Michael B; Klein, Ronald; Casavant, Thomas L; Scheetz, Todd E; Stone, Edwin M; Williams, Andrew B

    2007-05-01

    To use the power of knowledge acquisition and machine learning in the development of a collaborative computer classification system based on the features of age-related macular degeneration (AMD). A vocabulary was acquired from four AMD experts who examined 100 ophthalmoscopic images. The vocabulary was analyzed, hierarchically structured, and incorporated into a collaborative computer classification system called IDOCS. Using this system, three of the experts examined images from a second set of digital images compiled from more than 1000 patients with AMD. Images were annotated, and features were identified and defined. Decision trees, a machine learning method, were trained on the data collected and used to extract patterns. Interrelationships between the data from the different clinicians were investigated. Six drusen classes in the structured vocabulary were largely sufficient to describe all the identified features. The decision trees classified the data with 76.86% to 88.5% accuracy and distilled patterns in the form of hierarchical trees composed of 5 to 15 nodes. Experts were largely consistent in their characterization of soft, and to a lesser extent, hard drusen, but diverge in definition of other drusen. Size and crystalline morphology were the main determinants of drusen type across all experts. Machine learning is a powerful tool for the characterization of disease phenotypes. The creation of a defined feature set for AMD will facilitate the development of an IDOCS-based classification system.

  14. Real-time machine vision system using FPGA and soft-core processor

    Science.gov (United States)

    Malik, Abdul Waheed; Thörnberg, Benny; Meng, Xiaozhou; Imran, Muhammad

    2012-06-01

    This paper presents a machine vision system for real-time computation of distance and angle of a camera from reference points in the environment. Image pre-processing, component labeling and feature extraction modules were modeled at Register Transfer (RT) level and synthesized for implementation on field programmable gate arrays (FPGA). The extracted image component features were sent from the hardware modules to a soft-core processor, MicroBlaze, for computation of distance and angle. A CMOS imaging sensor operating at a clock frequency of 27MHz was used in our experiments to produce a video stream at the rate of 75 frames per second. Image component labeling and feature extraction modules were running in parallel having a total latency of 13ms. The MicroBlaze was interfaced with the component labeling and feature extraction modules through Fast Simplex Link (FSL). The latency for computing distance and angle of camera from the reference points was measured to be 2ms on the MicroBlaze, running at 100 MHz clock frequency. In this paper, we present the performance analysis, device utilization and power consumption for the designed system. The FPGA based machine vision system that we propose has high frame speed, low latency and a power consumption that is much lower compared to commercially available smart camera solutions.

  15. FUSION DECISION FOR A BIMODAL BIOMETRIC VERIFICATION SYSTEM USING SUPPORT VECTOR MACHINE AND ITS VARIATIONS

    Directory of Open Access Journals (Sweden)

    A. Teoh

    2017-12-01

    Full Text Available This paw presents fusion detection technique comparisons based on support vector machine and its variations for a bimodal biometric verification system that makes use of face images and speech utterances. The system is essentially constructed by a face expert, a speech expert and a fusion decision module. Each individual expert has been optimized to operate in automatic mode and designed for security access application. Fusion decision schemes considered are linear, weighted Support Vector Machine (SVM and linear SVM with quadratic transformation. The conditions tested include the balanced and unbalanced conditions between the two experts in order to obtain the optimum fusion module from  these techniques best suited to the target application.

  16. Machine Translation

    Indian Academy of Sciences (India)

    Research Mt System Example: The 'Janus' Translating Phone Project. The Janus ... based on laptops, and simultaneous translation of two speakers in a dialogue. For more ..... The current focus in MT research is on using machine learning.

  17. Intercultural design of man-machine systems: Machine design for the Chinese market; Interkulturelles Design fuer Mensch-Maschine-Systeme: Maschinendesign fuer den chinesischen Markt

    Energy Technology Data Exchange (ETDEWEB)

    Roese, K.; Zuehlke, D.; Liu, L. [Kaiserslautern Univ. (Germany)

    2002-07-01

    The ongoing globalization trend has imposed great needs on culture-specific machine design. For the expected business success on the foreign market the target user's special requirements should be well addressed. This paper proposes an effective approach to elicit user's culture-specific requirements on different machine design issues, which bases on the analysis of cultural environment and mentality. The approach was practically implemented in one project to elicit the user's requirements on machine design for the Chinese market. The investigation methods are briefly described and some most important culture specific design features for Mainland China are summarized. (orig.)

  18. Defining man-machine cooperation within complex systems: an ergonomic view of automation

    International Nuclear Information System (INIS)

    Lagrange, V.; Cara, F.

    1997-01-01

    Faced with the question of the optimal automation level in the operations of complex systems, ergonomists offer designers procedures, methods and criteria to take human factors into account. These means have been elaborated in the course of ergonomic interventions in projects at EDF. Based on knowledge of the operators' effective role they attempt to define, among the solutions that are technically possible, those that are desirable from the perspective of the whole man-machine system. (authors)

  19. Machining of Complex Sculptured Surfaces

    CERN Document Server

    2012-01-01

    The machining of complex sculptured surfaces is a global technological topic in modern manufacturing with relevance in both industrialized and emerging in countries particularly within the moulds and dies sector whose applications include highly technological industries such as the automotive and aircraft industry. Machining of Complex Sculptured Surfaces considers new approaches to the manufacture of moulds and dies within these industries. The traditional technology employed in the manufacture of moulds and dies combined conventional milling and electro-discharge machining (EDM) but this has been replaced with  high-speed milling (HSM) which has been applied in roughing, semi-finishing and finishing of moulds and dies with great success. Machining of Complex Sculptured Surfaces provides recent information on machining of complex sculptured surfaces including modern CAM systems and process planning for three and five axis machining as well as explanations of the advantages of HSM over traditional methods ra...

  20. Machine throughput improvement achieved using innovative control technique

    International Nuclear Information System (INIS)

    Sharma, V.; Acharya, S.; Mittal, K.C.

    2012-01-01

    In any type of fully or semi automatic machine the control systems plays an important role. The control system on the one hand has to consider the human psychology, intelligence requirement for an operator, and attention needed from him. On the other hand the complexity of the control has also to be understood well before designing a control system that can be handled comfortably and safely by the operator. As far as the user experience/comfort is concerned the design of control system GUI is vital. Considering these two aspects related to the user of the machine it is evident that the control system design is very important because it is has to accommodate the human behaviour and skill sets required/available as well as the capability of the machine under the control of the control system. An intelligently designed control system can enhance the productivity of the machine. (author)

  1. Quantum cloning machines and their implementation in physical systems

    International Nuclear Information System (INIS)

    Wu Tao; Ye Liu; Fang Bao-Long

    2013-01-01

    We review the basic theory of approximate quantum cloning for discrete variables and some schemes for implementing quantum cloning machines. Several types of approximate quantum clones and their expansive quantum clones are introduced. As for the implementation of quantum cloning machines, we review some design methods and recent experimental results. (topical review - quantum information)

  2. From 20th century metabolic wall charts to 21st century systems biology: database of mammalian metabolic enzymes.

    Science.gov (United States)

    Corcoran, Callan C; Grady, Cameron R; Pisitkun, Trairak; Parulekar, Jaya; Knepper, Mark A

    2017-03-01

    The organization of the mammalian genome into gene subsets corresponding to specific functional classes has provided key tools for systems biology research. Here, we have created a web-accessible resource called the Mammalian Metabolic Enzyme Database ( https://hpcwebapps.cit.nih.gov/ESBL/Database/MetabolicEnzymes/MetabolicEnzymeDatabase.html) keyed to the biochemical reactions represented on iconic metabolic pathway wall charts created in the previous century. Overall, we have mapped 1,647 genes to these pathways, representing ~7 percent of the protein-coding genome. To illustrate the use of the database, we apply it to the area of kidney physiology. In so doing, we have created an additional database ( Database of Metabolic Enzymes in Kidney Tubule Segments: https://hpcwebapps.cit.nih.gov/ESBL/Database/MetabolicEnzymes/), mapping mRNA abundance measurements (mined from RNA-Seq studies) for all metabolic enzymes to each of 14 renal tubule segments. We carry out bioinformatics analysis of the enzyme expression pattern among renal tubule segments and mine various data sources to identify vasopressin-regulated metabolic enzymes in the renal collecting duct. Copyright © 2017 the American Physiological Society.

  3. The importance of layout and configuration data for flexibility during commissionning and operation of the LHC machine protection systems

    CERN Document Server

    Mariethoz, Julien; Le Roux, Pascal; Bernard, Frederic; Harrison, Robert; Zerlauth, Markus

    2006-01-01

    Due to the large stored energies in both magnets and particle beams, the Large Hadron Collider (LHC) requires a large inventory of machine protection systems, as e.g. powering interlock systems, based on a series of distributed industrial controllers for the protection of the more than 10'000 normal and superconducting magnets. Such systems are required to be at the same time fast, reliable and secure but also flexible and configurable to allow for automated commissioning, remote monitoring and optimization during later operation. Based on the generic hardware architecture of the LHC machine protection systems presented at EPAC 2002 [2] and ICALEPS 2003, the use of configuration data for protection systems in view of the required reliability and safety is discussed. To achieve the very high level of reliability, it is required to use a coherent description of the layout of the accelerator components and of the associated machine protection architecture and their logical interconnections. Mechanisms to guarant...

  4. Reliable Software Development for Machine Protection Systems

    CERN Document Server

    Anderson, D; Dragu, M; Fuchsberger, K; Garnier, JC; Gorzawski, AA; Koza, M; Krol, K; Misiowiec, K; Stamos, K; Zerlauth, M

    2014-01-01

    The Controls software for the Large Hadron Collider (LHC) at CERN, with more than 150 millions lines of code, resides amongst the largest known code bases in the world1. Industry has been applying Agile software engineering techniques for more than two decades now, and the advantages of these techniques can no longer be ignored to manage the code base for large projects within the accelerator community. Furthermore, CERN is a particular environment due to the high personnel turnover and manpower limitations, where applying Agile processes can improve both, the codebase management as well as its quality. This paper presents the successful application of the Agile software development process Scrum for machine protection systems at CERN, the quality standards and infrastructure introduced together with the Agile process as well as the challenges encountered to adapt it to the CERN environment.

  5. Mechanical design of walking machines.

    Science.gov (United States)

    Arikawa, Keisuke; Hirose, Shigeo

    2007-01-15

    The performance of existing actuators, such as electric motors, is very limited, be it power-weight ratio or energy efficiency. In this paper, we discuss the method to design a practical walking machine under this severe constraint with focus on two concepts, the gravitationally decoupled actuation (GDA) and the coupled drive. The GDA decouples the driving system against the gravitational field to suppress generation of negative power and improve energy efficiency. On the other hand, the coupled drive couples the driving system to distribute the output power equally among actuators and maximize the utilization of installed actuator power. First, we depict the GDA and coupled drive in detail. Then, we present actual machines, TITAN-III and VIII, quadruped walking machines designed on the basis of the GDA, and NINJA-I and II, quadruped wall walking machines designed on the basis of the coupled drive. Finally, we discuss walking machines that travel on three-dimensional terrain (3D terrain), which includes the ground, walls and ceiling. Then, we demonstrate with computer simulation that we can selectively leverage GDA and coupled drive by walking posture control.

  6. Modeling a ground-coupled heat pump system by a support vector machine

    Energy Technology Data Exchange (ETDEWEB)

    Esen, Hikmet; Esen, Mehmet [Department of Mechanical Education, Faculty of Technical Education, Firat University, 23119 Elazig (Turkey); Inalli, Mustafa [Department of Mechanical Engineering, Faculty of Engineering, Firat University, 23279 Elazig (Turkey); Sengur, Abdulkadir [Department of Electronic and Computer Science, Faculty of Technical Education, Firat University, 23119 Elazig (Turkey)

    2008-08-15

    This paper reports on a modeling study of ground coupled heat pump (GCHP) system performance (COP) by using a support vector machine (SVM) method. A GCHP system is a multi-variable system that is hard to model by conventional methods. As regards the SVM, it has a superior capability for generalization, and this capability is independent of the dimensionality of the input data. In this study, a SVM based method was intended to adopt GCHP system for efficient modeling. The Lin-kernel SVM method was quite efficient in modeling purposes and did not require a pre-knowledge about the system. The performance of the proposed methodology was evaluated by using several statistical validation parameters. It is found that the root-mean squared (RMS) value is 0.002722, the coefficient of multiple determinations (R{sup 2}) value is 0.999999, coefficient of variation (cov) value is 0.077295, and mean error function (MEF) value is 0.507437 for the proposed Lin-kernel SVM method. The optimum parameters of the SVM method were determined by using a greedy search algorithm. This search algorithm was effective for obtaining the optimum parameters. The simulation results show that the SVM is a good method for prediction of the COP of the GCHP system. The computation of SVM model is faster compared with other machine learning techniques (artificial neural networks (ANN) and adaptive neuro-fuzzy inference system (ANFIS)); because there are fewer free parameters and only support vectors (only a fraction of all data) are used in the generalization process. (author)

  7. Comparison of drive systems for pulsed synchronous machines - an overview

    International Nuclear Information System (INIS)

    Baumgart, G.E.; Boenig, H.J.

    1986-01-01

    Magnetically confined plasma fusion experiments require large pulses of energy to be delivered into coil systems. One of the most effective methods of generating these high energy pulses is to convert stored inertial energy into electrical energy. Large synchronous generators of both the vertical and horizontal shaft type have been successfully used for this purpose. As the pulsed energy is delivered to the load, the inertial energy of the rotor of the machine is changed into electrical energy, causing the rotor to slow down. A drive system is required to accelerate the generator from standstill to the maximum operating speed and between load pulses from a reduced operating speed to the maximum speed. There are several types of drive systems that can be used for this application. An overview of six candidate drive systems is presented and comparisons of cost, performance, efficiency and line effects for these systems are described

  8. Comparison of drive systems for pulsed synchronous machines: an overview

    International Nuclear Information System (INIS)

    Baumgart, G.E.; Boenig, H.J.

    1985-01-01

    Magnetically confined plasma fusion experiments require large pulses of energy to be delivered into coil systems. One of the most effective methods of generating these high energy pulses is to convert stored inertial energy into electrical energy. Large synchronous generators of both the vertical and horizontal shaft type have been successfully used for this purpose. As the pulsed energy is delivered to the load, the inertial energy of the rotor of the machine is changed into electrical energy, causing the rotor to slow down. A drive system is required to accelerate the generator from standstill to the maximum operating speed and between load pulses from a reduced operating speed to the maximum speed. There are several types of drive systems that can be used for this application. An overview of six candidate drive systems is presented and comparisons of cost, performance, efficiency, and line effects for these systems are described

  9. Implementation of the Lanczos algorithm for the Hubbard model on the Connection Machine system

    International Nuclear Information System (INIS)

    Leung, P.W.; Oppenheimer, P.E.

    1992-01-01

    An implementation of the Lanczos algorithm for the exact diagonalization of the two dimensional Hubbard model on a 4x4 square lattice on the Connection Machine CM-2 system is described. The CM-2 is a massively parallel machine with distributed memory. The program is written in C/PARIS. This implementation minimizes memory usage by generating the matrix elements as needed instead of storing them. The Lanczos vectors are stored across the local memory of the processors. Using translational symmetry only, the dimension of the Hilbert space at half filling is more than 10 million. A speed of about 2.4 min per iteration is achieved on a 64K CM-2. This implementation is scalable. Running it on a bigger machine with more processors speeds up the process. The performance analysis of this implementation is shown and discuss its advantages and disadvantages are discussed

  10. Miniaturisation of Pressure-Sensitive Paint Measurement Systems Using Low-Cost, Miniaturised Machine Vision Cameras.

    Science.gov (United States)

    Quinn, Mark Kenneth; Spinosa, Emanuele; Roberts, David A

    2017-07-25

    Measurements of pressure-sensitive paint (PSP) have been performed using new or non-scientific imaging technology based on machine vision tools. Machine vision camera systems are typically used for automated inspection or process monitoring. Such devices offer the benefits of lower cost and reduced size compared with typically scientific-grade cameras; however, their optical qualities and suitability have yet to be determined. This research intends to show relevant imaging characteristics and also show the applicability of such imaging technology for PSP. Details of camera performance are benchmarked and compared to standard scientific imaging equipment and subsequent PSP tests are conducted using a static calibration chamber. The findings demonstrate that machine vision technology can be used for PSP measurements, opening up the possibility of performing measurements on-board small-scale model such as those used for wind tunnel testing or measurements in confined spaces with limited optical access.

  11. Miniaturisation of Pressure-Sensitive Paint Measurement Systems Using Low-Cost, Miniaturised Machine Vision Cameras

    Directory of Open Access Journals (Sweden)

    Mark Kenneth Quinn

    2017-07-01

    Full Text Available Measurements of pressure-sensitive paint (PSP have been performed using new or non-scientific imaging technology based on machine vision tools. Machine vision camera systems are typically used for automated inspection or process monitoring. Such devices offer the benefits of lower cost and reduced size compared with typically scientific-grade cameras; however, their optical qualities and suitability have yet to be determined. This research intends to show relevant imaging characteristics and also show the applicability of such imaging technology for PSP. Details of camera performance are benchmarked and compared to standard scientific imaging equipment and subsequent PSP tests are conducted using a static calibration chamber. The findings demonstrate that machine vision technology can be used for PSP measurements, opening up the possibility of performing measurements on-board small-scale model such as those used for wind tunnel testing or measurements in confined spaces with limited optical access.

  12. Effect of Stiffness of Rolling Joints on the Dynamic Characteristic of Ball Screw Feed Systems in a Milling Machine

    Directory of Open Access Journals (Sweden)

    Dazhong Wang

    2015-01-01

    Full Text Available Dynamic characteristic of ball screw feed system in a milling machine is studied numerically in this work. In order to avoid the difficulty in determining the stiffness of rolling joints theoretically, a dynamic modeling method for analyzing the feed system is discussed, and a stiffness calculation method of the rolling joints is proposed based on the Hertz contact theory. Taking a 3-axis computer numerical control (CNC milling machine set ermined as a research object, the stiffness of its fixed joint between the column and the body together with the stiffness parameters of the rolling joints is evaluated according to the Takashi Yoshimura method. Then, a finite element (FE model is established for the machine tool. The correctness of the FE model and the stiffness calculation method of the rolling joints are validated by theoretical and experimental modal analysis results of the machine tool’s workbench. Under the two modeling methods of joints incorporating the stiffness parameters and rigid connection, a theoretical modal analysis is conducted for the CNC milling machine. The natural frequencies and modal shapes reveal that the joints’ dynamic characteristic has an important influence on the dynamic performance of a whole machine tool, especially for the case with natural frequency and higher modes.

  13. Feeding Our Immune System: Impact on Metabolism

    Directory of Open Access Journals (Sweden)

    Isabelle Wolowczuk

    2008-01-01

    Full Text Available Endogenous intestinal microflora and environmental factors, such as diet, play a central role in immune homeostasis and reactivity. In addition, microflora and diet both influence body weight and insulin-resistance, notably through an action on adipose cells. Moreover, it is known since a long time that any disturbance in metabolism, like obesity, is associated with immune alteration, for example, inflammation. The purpose of this review is to provide an update on how nutrients-derived factors (mostly focusing on fatty acids and glucose impact the innate and acquired immune systems, including the gut immune system and its associated bacterial flora. We will try to show the reader how the highly energy-demanding immune cells use glucose as a main source of fuel in a way similar to that of insulin-responsive adipose tissue and how Toll-like receptors (TLRs of the innate immune system, which are found on immune cells, intestinal cells, and adipocytes, are presently viewed as essential actors in the complex balance ensuring bodily immune and metabolic health. Understanding more about these links will surely help to study and understand in a more fundamental way the common observation that eating healthy will keep you and your immune system healthy.

  14. 4th International Conference on Man–Machine Interactions

    CERN Document Server

    Brachman, Agnieszka; Kozielski, Stanisław; Czachórski, Tadeusz

    2016-01-01

    This book provides an overview of the current state of research on development and application of methods, algorithms, tools and systems associated with the studies on man-machine interaction. Modern machines and computer systems are designed not only to process information, but also to work in dynamic environment, supporting or even replacing human activities in areas such as business, industry, medicine or military. The interdisciplinary field of research on man-machine interactions focuses on broad range of aspects related to the ways in which human make or use computational artifacts, systems and infrastructure.   This monograph is the fourth edition in the series and presents new concepts concerning analysis, design and evaluation of man-machine systems. The selection of high-quality, original papers covers a wide scope of research topics focused on the main problems and challenges encountered within rapidly evolving new forms of human-machine relationships. The presented material is structured into fol...

  15. Towards Measuring the Abstractness of State Machines based on Mutation Testing

    Directory of Open Access Journals (Sweden)

    Thomas Baar

    2017-01-01

    Full Text Available Abstract. The notation of state machines is widely adopted as a formalism to describe the behaviour of systems. Usually, multiple state machine models can be developed for the very same software system. Some of these models might turn out to be equivalent, but, in many cases, different state machines describing the same system also differ in their level of abstraction. In this paper, we present an approach to actually measure the abstractness level of state machines w.r.t. a given implemented software system. A state machine is considered to be less abstract when it is conceptionally closer to the implemented system. In our approach, this distance between state machine and implementation is measured by applying coverage criteria known from software mutation testing. Abstractness of state machines can be considered as a new metric. As for other metrics as well, a known value for the abstractness of a given state machine allows to assess its quality in terms of a simple number. In model-based software development projects, the abstract metric can help to prevent model degradation since it can actually measure the semantic distance from the behavioural specification of a system in form of a state machine to the current implementation of the system. In contrast to other metrics for state machines, the abstractness cannot be statically computed based on the state machine’s structure, but requires to execute both state machine and corresponding system implementation. The article is published in the author’s wording. 

  16. Behavioral simulation of a nuclear power plant operator crew for human-machine system design

    International Nuclear Information System (INIS)

    Furuta, K.; Shimada, T.; Kondo, S.

    1999-01-01

    This article proposes an architecture of behavioral simulation of an operator crew in a nuclear power plant including group processes and interactions between the operators and their working environment. An operator model was constructed based on the conceptual human information processor and then substantiated as a knowledge-based system with multiple sets of knowledge base and blackboard, each of which represents an individual operator. From a trade-off between reality and practicality, we adopted an architecture of simulation that consists of the operator, plant and environment models in order to consider operator-environment interactions. The simulation system developed on this framework and called OCCS was tested using a scenario of BWR plant operation. The case study showed that operator-environment interactions have significant effects on operator crew performance and that they should be considered properly for simulating behavior of human-machine systems. The proposed architecture contributed to more realistic simulation in comparison with an experimental result, and a good prospect has been obtained that computer simulation of an operator crew is feasible and useful for human-machine system design. (orig.)

  17. Human friendly man-machine system with advanced media technology

    International Nuclear Information System (INIS)

    Ogino, Takamichi; Sasaki, Kazunori

    1993-01-01

    This paper deals with the methodology to implement the man-machine system (MMS) with enhanced human friendliness for nuclear power plants. The relevant technologies are investigated from the two view points: One is integrated multi-media usage for user-computer interface and the other cognitive engineering for user-task interaction. Promising MMS design methodologies, concepts, and their limitations are discussed. To overcome uncertain factors found in human behaviors or individual differences in performance and preference of operators, a design appproach to natural and flexible man-computer interactive environment is proposed by intergrated use of not only cognitive and psychological knowledge but also advanced media technology. Multi-media operator support system under development is shown as an example to evaluate the effectiveness of the new approach and future advancement is prospected. (orig.)

  18. FSW of Aluminum Tailor Welded Blanks across Machine Platforms

    Energy Technology Data Exchange (ETDEWEB)

    Hovanski, Yuri; Upadhyay, Piyush; Carlson, Blair; Szymanski, Robert; Luzanski, Tom; Marshall, Dustin

    2015-02-16

    Development and characterization of friction stir welded aluminum tailor welded blanks was successfully carried out on three separate machine platforms. Each was a commercially available, gantry style, multi-axis machine designed specifically for friction stir welding. Weld parameters were developed to support high volume production of dissimilar thickness aluminum tailor welded blanks at speeds of 3 m/min and greater. Parameters originally developed on an ultra-high stiffness servo driven machine where first transferred to a high stiffness servo-hydraulic friction stir welding machine, and subsequently transferred to a purpose built machine designed to accommodate thin sheet aluminum welding. The inherent beam stiffness, bearing compliance, and control system for each machine were distinctly unique, which posed specific challenges in transferring welding parameters across machine platforms. This work documents the challenges imposed by successfully transferring weld parameters from machine to machine, produced from different manufacturers and with unique control systems and interfaces.

  19. Smith machine counterbalance system affects measures of maximal bench press throw performance.

    Science.gov (United States)

    Vingren, Jakob L; Buddhadev, Harsh H; Hill, David W

    2011-07-01

    Equipment with counterbalance weight systems is commonly used for the assessment of performance in explosive resistance exercise movements, but it is not known if such systems affect performance measures. The purpose of this study was to determine the effect of using a counterbalance weight system on measures of smith machine bench press throw performance. Ten men and 14 women (mean ± SD: age, 25 ± 4 years; height, 173 ± 10 cm; weight, 77.7 ± 18.3 kg) completed maximal smith machine bench press throws under 4 different conditions (2 × 2; counterbalance × load): with or without a counterbalance weight system and using 'light' or 'moderate' net barbell loads. Performance variables (peak force, peak velocity, and peak power) were measured using a linear accelerometer attached to the barbell. The counterbalance weight system resulted in significant (p velocity (light: -0.49 ± 0.10 m·s; moderate: -0.33 ± 0.07 m·s), and peak power (light: -220 ± 43 W; moderate: -143 ± 28 W) compared with no counterbalance system for both load conditions. Load condition did not affect absolute or percentage reductions from the counterbalance weight system for any variable. In conclusion, the use of a counterbalance weight system reduces accelerometer-based performance measures for the bench press throw exercise at light and moderate loads. This reduction in measures is likely because of an increase in the external resistance during the movement, which results in a discrepancy between the manually input and the actual value for external load. A counterbalance weight system should not be used when measuring performance in explosive resistance exercises with an accelerometer.

  20. Virtual machining considering dimensional, geometrical and tool deflection errors in three-axis CNC milling machines

    OpenAIRE

    Soori, Mohsen; Arezoo, Behrooz; Habibi, Mohsen

    2014-01-01

    Virtual manufacturing systems can provide useful means for products to be manufactured without the need of physical testing on the shop floor. As a result, the time and cost of part production can be decreased. There are different error sources in machine tools such as tool deflection, geometrical deviations of moving axis and thermal distortions of machine tool structures. Some of these errors can be decreased by controlling the machining process and environmental parameters. However other e...

  1. Virtual machining considering dimensional, geometrical and tool deflection errors in three-axis CNC milling machines

    OpenAIRE

    Soori, Mohsen; Arezoo, Behrooz; Habibi, Mohsen

    2016-01-01

    Virtual manufacturing systems can provide useful means for products to be manufactured without the need of physical testing on the shop floor. As a result, the time and cost of part production can be decreased. There are different error sources in machine tools such as tool deflection, geometrical deviations of moving axis and thermal distortions of machine tool structures. Some of these errors can be decreased by controlling the machining process and environmental parameters. However other e...

  2. Throughput centered prioritization of machines in transfer lines

    International Nuclear Information System (INIS)

    Pascual, R.; Godoy, D.; Louit, D.M.

    2011-01-01

    In an environment of scarce resources and complex production systems, prioritizing is key to confront the challenge of managing physical assets. In the literature, there exist a number of techniques to prioritize maintenance decisions that consider safety, technical and business perspectives. However, the effect of risk mitigating elements-such as intermediate buffers in production lines-on prioritization has not yet been investigated in depth. In this line, the work proposes a user-friendly graphical technique called the system efficiency influence diagram (SEID). Asset managers may use SEID to identify machines that have a greater impact on the system throughput, and thus set prioritized maintenance policies and/or redesign of buffers capacities. The tool provides insight to the analyst as it decomposes the influence of a given machine on the system throughput as a product of two elements: (1) system influence efficiency factor and (2) machine unavailability factor. We illustrate its applicability using three case studies: a four-machine transfer line, a vehicle assembly line, and an open-pit mining conveyor system. The results confirm that the machines with greater unavailability factors are not necessarily the most important for the efficiency of the production line, as it is the case when no intermediate buffers exist. As a decision aid tool, SEID emphasizes the need to move from a maintenance vision focused on machine availability, to a systems engineering perspective. - Highlights: → We propose a graphical technique to prioritize machines in production lines. → The tool is called 'system efficiency influence diagram' (SEID). → It helps setting prioritized maintenance policies and/or redesign of buffers. → The SEID technique focuses on system efficiency and throughput. → We illustrate its applicability using three case studies.

  3. Machine learning an artificial intelligence approach

    CERN Document Server

    Banerjee, R; Bradshaw, Gary; Carbonell, Jaime Guillermo; Mitchell, Tom Michael; Michalski, Ryszard Spencer

    1983-01-01

    Machine Learning: An Artificial Intelligence Approach contains tutorial overviews and research papers representative of trends in the area of machine learning as viewed from an artificial intelligence perspective. The book is organized into six parts. Part I provides an overview of machine learning and explains why machines should learn. Part II covers important issues affecting the design of learning programs-particularly programs that learn from examples. It also describes inductive learning systems. Part III deals with learning by analogy, by experimentation, and from experience. Parts IV a

  4. A modern approach for the realisation of the man-machine information system

    International Nuclear Information System (INIS)

    Martin, D.; Grensemann, D.

    1980-01-01

    The tool for man-machine communication has been given the name VISCOMP-VISual COmmunication Man-Process. Dependent on the project implementation phase VISCOMP functions either autonomously (planning and definition phases) or in conjunction with a data acquisition system during the operational phase on the plant. The relationship of the required components to the project phases is illustrated. (orig./HP)

  5. A Machine Learning-based Rainfall System for GPM Dual-frequency Radar

    Science.gov (United States)

    Tan, H.; Chandrasekar, V.; Chen, H.

    2017-12-01

    Precipitation measurement produced by the Global Precipitation Measurement (GPM) Dual-frequency Precipitation Radar (DPR) plays an important role in researching the water circle and forecasting extreme weather event. Compare with its predecessor - Tropical Rainfall Measuring Mission (TRMM) Precipitation Radar (PR), GRM DPR measures precipitation in two different frequencies (i.e., Ku and Ka band), which can provide detailed information on the microphysical properties of precipitation particles, quantify particle size distribution and quantitatively measure light rain and falling snow. This paper presents a novel Machine Learning system for ground-based and space borne radar rainfall estimation. The system first trains ground radar data for rainfall estimation using rainfall measurements from gauges and subsequently uses the ground radar based rainfall estimates to train GPM DPR data in order to get space based rainfall product. Therein, data alignment between space DPR and ground radar is conducted using the methodology proposed by Bolen and Chandrasekar (2013), which can minimize the effects of potential geometric distortion of GPM DPR observations. For demonstration purposes, rainfall measurements from three rain gauge networks near Melbourne, Florida, are used for training and validation purposes. These three gauge networks, which are located in Kennedy Space Center (KSC), South Florida Water Management District (SFL), and St. Johns Water Management District (STJ), include 33, 46, and 99 rain gauge stations, respectively. Collocated ground radar observations from the National Weather Service (NWS) Weather Surveillance Radar - 1988 Doppler (WSR-88D) in Melbourne (i.e., KMLB radar) are trained with the gauge measurements. The trained model is then used to derive KMLB radar based rainfall product, which is used to train GPM DPR data collected from coincident overpasses events. The machine learning based rainfall product is compared against the GPM standard products

  6. Ideology of a multiparametric system for estimating the insulation system of electric machines on the basis of absorption testing methods

    Science.gov (United States)

    Kislyakov, M. A.; Chernov, V. A.; Maksimkin, V. L.; Bozhin, Yu. M.

    2017-12-01

    The article deals with modern methods of monitoring the state and predicting the life of electric machines. In 50% of the cases of failure in the performance of electric machines is associated with insulation damage. As promising, nondestructive methods of control, methods based on the investigation of the processes of polarization occurring in insulating materials are proposed. To improve the accuracy of determining the state of insulation, a multiparametric approach is considered, which is a basis for the development of an expert system for estimating the state of health.

  7. Towards systems metabolic engineering in Pichia pastoris.

    Science.gov (United States)

    Schwarzhans, Jan-Philipp; Luttermann, Tobias; Geier, Martina; Kalinowski, Jörn; Friehs, Karl

    2017-11-01

    The methylotrophic yeast Pichia pastoris is firmly established as a host for the production of recombinant proteins, frequently outperforming other heterologous hosts. Already, a sizeable amount of systems biology knowledge has been acquired for this non-conventional yeast. By applying various omics-technologies, productivity features have been thoroughly analyzed and optimized via genetic engineering. However, challenging clonal variability, limited vector repertoire and insufficient genome annotation have hampered further developments. Yet, in the last few years a reinvigorated effort to establish P. pastoris as a host for both protein and metabolite production is visible. A variety of compounds from terpenoids to polyketides have been synthesized, often exceeding the productivity of other microbial systems. The clonal variability was systematically investigated and strategies formulated to circumvent untargeted events, thereby streamlining the screening procedure. Promoters with novel regulatory properties were discovered or engineered from existing ones. The genetic tractability was increased via the transfer of popular manipulation and assembly techniques, as well as the creation of new ones. A second generation of sequencing projects culminated in the creation of the second best functionally annotated yeast genome. In combination with landmark physiological insights and increased output of omics-data, a good basis for the creation of refined genome-scale metabolic models was created. The first application of model-based metabolic engineering in P. pastoris showcased the potential of this approach. Recent efforts to establish yeast peroxisomes for compartmentalized metabolite synthesis appear to fit ideally with the well-studied high capacity peroxisomal machinery of P. pastoris. Here, these recent developments are collected and reviewed with the aim of supporting the establishment of systems metabolic engineering in P. pastoris. Copyright © 2017. Published

  8. Tomato grading system using machine vision technology and neuro-fuzzy networks (ANFIS

    Directory of Open Access Journals (Sweden)

    H Izadi

    2016-04-01

    Full Text Available Introduction: The quality of agricultural products is associated with their color, size and health, grading of fruits is regarded as an important step in post-harvest processing. In most cases, manual sorting inspections depends on available manpower, time consuming and their accuracy could not be guaranteed. Machine Vision is known to be a useful tool for external features measurement (e.g. size, shape, color and defects and in recent century, Machine Vision technology has been used for shape sorting. The main purpose of this study was to develop new method for tomato grading and sorting using Neuro-fuzzy system (ANFIS and to compare the accuracies of the ANFIS predicted results with those suggested by a human expert. Materials and Methods: In this study, a total of 300 image of tomatoes (Rev ground was randomly harvested, classified in 3 ripeness stage, 3 sizes and 2 health. The grading and sorting mechanism consisted of a lighting chamber (cloudy sky, lighting source and a digital camera connected to a computer. The images were recorded in a special chamber with an indirect radiation (cloudy sky with four florescent lampson each sides and camera lens was entire to lighting chamber by a hole which was only entranced to outer and covered by a camera lens. Three types of features were extracted from final images; Shap, color and texture. To receive these features, we need to have images both in color and binary format in procedure shown in Figure 1. For the first group; characteristics of the images were analysis that could offer information an surface area (S.A., maximum diameter (Dmax, minimum diameter (Dmin and average diameters. Considering to the importance of the color in acceptance of food quality by consumers, the following classification was conducted to estimate the apparent color of the tomato; 1. Classified as red (red > 90% 2. Classified as red light (red or bold pink 60-90% 3. Classified as pink (red 30-60% 4. Classified as Turning

  9. Dynamic analysis and vibration testing of CFRP drive-line system used in heavy-duty machine tool

    Directory of Open Access Journals (Sweden)

    Mo Yang

    2018-03-01

    Full Text Available Low critical rotary speed and large vibration in the metal drive-line system of heavy-duty machine tool affect the machining precision seriously. Replacing metal drive-line with the CFRP drive-line can effectively solve this problem. Based on the composite laminated theory and the transfer matrix method (TMM, this paper puts forward a modified TMM to analyze dynamic characteristics of CFRP drive-line system. With this modified TMM, the CFRP drive-line of a heavy vertical miller is analyzed. And the finite element modal analysis model of the shafting is established. The results of the modified TMM and finite element analysis (FEA show that the modified TMM can effectively predict the critical rotary speed of CFRP drive-line. And the critical rotary speed of CFRP drive-line is 20% higher than that of the original metal drive-line. Then, the vibration of the CFRP and the metal drive-line were tested. The test results show that application of the CFRP drive shaft in the drive-line can effectively reduce the vibration of the heavy-duty machine tool. Keywords: CFRP drive-line system, Dynamic behavior, Transfer matrix, Vibration measurement

  10. TMI-2 core boring machine

    International Nuclear Information System (INIS)

    Croft, K.M.; Helbert, H.J.; Laney, W.M.

    1986-01-01

    An important and essential aspect of the TMI-2 defueling effort is to determine what occurred in the core region during the accident. Remote cameras and probes only portray a portion of the overall picture. What lies beneath the rubble bed and solidified sublayer is, as yet, unknown. This paper discusses the TMI-2 Core Boring Machine, which has been developed to drill into the damaged core of the TMI-2 reactor and extract stratified samples of the core. This machine, its unique support structure, positioning and leveling systems, and specially designed drill bits, combine to provide a unique mechanical system. In addition, the machine is controlled by a microprocessor; which actually controls the drilling operation, allowing relatively inexperienced operators to drill the core samples. A data acquisition system is data integral with the controlling system and collects data relative to system conditions and monitored parameters during drilling. Data obtained during the actual drilling operations are collected in a data base which will be used for actual mapping of the core region, identifying materials and stratification levels that are present

  11. Robotic refueling machine

    International Nuclear Information System (INIS)

    Challberg, R.C.; Jones, C.R.

    1996-01-01

    One of the longest critical path operations performed during the outage is removing and replacing the fuel. A design is currently under development for a refueling machine which would allow faster, fully automated operation and would also allow the handling of two fuel assemblies at the same time. This design is different from current designs, (a) because of its lighter weight, making increased acceleration and speed possible, (b) because of its control system which makes locating the fuel assembly more dependable and faster, and (c) because of its dual handling system allowing simultaneous fuel movements. The new design uses two robotic arms to span a designated area of the vessel and the fuel storage area. Attached to the end of each robotic arm is a lightweight telescoping mast with a pendant attached to the end of each mast. The pendant acts as the base unit, allowing attachment of any number of end effectors depending on the servicing or inspection operation. Housed within the pendant are two television cameras used for the positioning control system. The control system is adapted from the robotics field using the technology known as machine vision, which provides both object and character recognition techniques to enable relative position control rather than absolute position control as in past designs. The pendant also contains thrusters that are used for fast, short distance, precise positioning. The new refueling machine system design is capable of a complete off load and reload of an 872 element core in about 5.3 days compared to 13 days for a conventional system

  12. The use of machine learning and nonlinear statistical tools for ADME prediction.

    Science.gov (United States)

    Sakiyama, Yojiro

    2009-02-01

    Absorption, distribution, metabolism and excretion (ADME)-related failure of drug candidates is a major issue for the pharmaceutical industry today. Prediction of ADME by in silico tools has now become an inevitable paradigm to reduce cost and enhance efficiency in pharmaceutical research. Recently, machine learning as well as nonlinear statistical tools has been widely applied to predict routine ADME end points. To achieve accurate and reliable predictions, it would be a prerequisite to understand the concepts, mechanisms and limitations of these tools. Here, we have devised a small synthetic nonlinear data set to help understand the mechanism of machine learning by 2D-visualisation. We applied six new machine learning methods to four different data sets. The methods include Naive Bayes classifier, classification and regression tree, random forest, Gaussian process, support vector machine and k nearest neighbour. The results demonstrated that ensemble learning and kernel machine displayed greater accuracy of prediction than classical methods irrespective of the data set size. The importance of interaction with the engineering field is also addressed. The results described here provide insights into the mechanism of machine learning, which will enable appropriate usage in the future.

  13. Development of Machinable Ellipses by NURBS Curves

    OpenAIRE

    Yuan L. Lai; Jian H. Chen; Jui P. Hung

    2008-01-01

    Owning to the high-speed feed rate and ultra spindle speed have been used in modern machine tools, the tool-path generation plays a key role in the successful application of a High-Speed Machining (HSM) system. Because of its importance in both high-speed machining and tool-path generation, approximating a contour by NURBS format is a potential function in CAD/CAM/CNC systems. It is much more convenient to represent an ellipse by parametric form than to connect points lab...

  14. Dynamic State Estimation for Multi-Machine Power System by Unscented Kalman Filter With Enhanced Numerical Stability

    Energy Technology Data Exchange (ETDEWEB)

    Qi, Junjian; Sun, Kai; Wang, Jianhui; Liu, Hui

    2018-03-01

    In this paper, in order to enhance the numerical stability of the unscented Kalman filter (UKF) used for power system dynamic state estimation, a new UKF with guaranteed positive semidifinite estimation error covariance (UKFGPS) is proposed and compared with five existing approaches, including UKFschol, UKF-kappa, UKFmodified, UKF-Delta Q, and the squareroot UKF (SRUKF). These methods and the extended Kalman filter (EKF) are tested by performing dynamic state estimation on WSCC 3-machine 9-bus system and NPCC 48-machine 140-bus system. For WSCC system, all methods obtain good estimates. However, for NPCC system, both EKF and the classic UKF fail. It is found that UKFschol, UKF-kappa, and UKF-Delta Q do not work well in some estimations while UKFGPS works well in most cases. UKFmodified and SRUKF can always work well, indicating their better scalability mainly due to the enhanced numerical stability.

  15. Considerations upon the Machine Learning Technologies

    OpenAIRE

    Alin Munteanu; Cristina Ofelia Sofran

    2006-01-01

    Artificial intelligence offers superior techniques and methods by which problems from diverse domains may find an optimal solution. The Machine Learning technologies refer to the domain of artificial intelligence aiming to develop the techniques allowing the computers to “learn”. Some systems based on Machine Learning technologies tend to eliminate the necessity of the human intelligence while the others adopt a man-machine collaborative approach.

  16. [A new machinability test machine and the machinability of composite resins for core built-up].

    Science.gov (United States)

    Iwasaki, N

    2001-06-01

    A new machinability test machine especially for dental materials was contrived. The purpose of this study was to evaluate the effects of grinding conditions on machinability of core built-up resins using this machine, and to confirm the relationship between machinability and other properties of composite resins. The experimental machinability test machine consisted of a dental air-turbine handpiece, a control weight unit, a driving unit of the stage fixing the test specimen, and so on. The machinability was evaluated as the change in volume after grinding using a diamond point. Five kinds of core built-up resins and human teeth were used in this study. The machinabilities of these composite resins increased with an increasing load during grinding, and decreased with repeated grinding. There was no obvious correlation between the machinability and Vickers' hardness; however, a negative correlation was observed between machinability and scratch width.

  17. Spatial organization of heterologous metabolic system in vivo based on TALE.

    Science.gov (United States)

    Zhu, Lv-yun; Qiu, Xin-Yuan; Zhu, Ling-Yun; Wu, Xiao-Min; Zhang, Yuan; Zhu, Qian-Hui; Fan, Dong-Yu; Zhu, Chu-Shu; Zhang, Dong-Yi

    2016-05-17

    For years, prokaryotic hosts have been widely applied in bio-engineering. However, the confined in vivo enzyme clustering of heterologous metabolic pathways in these organisms often results in low local concentrations of enzymes and substrates, leading to a low productive efficacy. We developed a new method to accelerate a heterologous metabolic system by integrating a transcription activator-like effector (TALE)-based scaffold system into an Escherichia coli chassis. The binding abilities of the TALEs to the artificial DNA scaffold were measured through ChIP-PCR. The effect of the system was determined through a split GFP study and validated through the heterologous production of indole-3-acetic acid (IAA) by incorporating TALE-fused IAA biosynthetic enzymes in E. coli. To the best of our knowledge, we are the first to use the TALE system as a scaffold for the spatial organization of bacterial metabolism. This technique might be used to establish multi-enzymatic reaction programs in a prokaryotic chassis for various applications.

  18. Development of PC based data acquisition system for universal test machine

    International Nuclear Information System (INIS)

    Nageswara Rao, T.S.V.R.; Hari Prasad, V.; Satyadev, B.; Banarjee, P.K.

    2010-01-01

    To determine the tensile properties of nuclear fuel tubes and other components, the Universal Test Machine is being used in Material testing section of Quality Assurance, NFC. This machine consists of Chart Recorder to chart the Load Vs. Strain graph. The tensile properties of the test material viz. Ultimate Tensile Strength (UTS), Yield Strength (YS), and Young's Modulus (e) etc. are usually determined by graphical method using a ruler. To overcome the problems faced due to embargo and non-availability of spares of recorder, a PC based Data Acquisition System (DAS) with necessary software algorithm was developed for automatic calculation of tensile properties by extracting the linear portion of tensile test curve where the Tangent and Secant Modulus coincide, without intervention of the user. This developmental work reduces human error in calculation, facilitates the use of state-of-the art technology and the risk of obsolescence by employing PC based architecture. (author)

  19. The cognitive approach to conscious machines

    CERN Document Server

    Haikonen, Pentti O

    2003-01-01

    Could a machine have an immaterial mind? The author argues that true conscious machines can be built, but rejects artificial intelligence and classical neural networks in favour of the emulation of the cognitive processes of the brain-the flow of inner speech, inner imagery and emotions. This results in a non-numeric meaning-processing machine with distributed information representation and system reactions. It is argued that this machine would be conscious; it would be aware of its own existence and its mental content and perceive this as immaterial. Novel views on consciousness and the mind-

  20. Metabolic network prediction through pairwise rational kernels.

    Science.gov (United States)

    Roche-Lima, Abiel; Domaratzki, Michael; Fristensky, Brian

    2014-09-26

    Metabolic networks are represented by the set of metabolic pathways. Metabolic pathways are a series of biochemical reactions, in which the product (output) from one reaction serves as the substrate (input) to another reaction. Many pathways remain incompletely characterized. One of the major challenges of computational biology is to obtain better models of metabolic pathways. Existing models are dependent on the annotation of the genes. This propagates error accumulation when the pathways are predicted by incorrectly annotated genes. Pairwise classification methods are supervised learning methods used to classify new pair of entities. Some of these classification methods, e.g., Pairwise Support Vector Machines (SVMs), use pairwise kernels. Pairwise kernels describe similarity measures between two pairs of entities. Using pairwise kernels to handle sequence data requires long processing times and large storage. Rational kernels are kernels based on weighted finite-state transducers that represent similarity measures between sequences or automata. They have been effectively used in problems that handle large amount of sequence information such as protein essentiality, natural language processing and machine translations. We create a new family of pairwise kernels using weighted finite-state transducers (called Pairwise Rational Kernel (PRK)) to predict metabolic pathways from a variety of biological data. PRKs take advantage of the simpler representations and faster algorithms of transducers. Because raw sequence data can be used, the predictor model avoids the errors introduced by incorrect gene annotations. We then developed several experiments with PRKs and Pairwise SVM to validate our methods using the metabolic network of Saccharomyces cerevisiae. As a result, when PRKs are used, our method executes faster in comparison with other pairwise kernels. Also, when we use PRKs combined with other simple kernels that include evolutionary information, the accuracy

  1. CAE Analysis of Secondary Shaft Systems in Great Five-axis Turning-Milling Complex CNC Machine

    Directory of Open Access Journals (Sweden)

    Chih-Chiang Hong

    2018-01-01

    Full Text Available The commercial computer aided engineering (CAE software is used to analyze the linear-static construction, stress and deformation for the secondary shaft systems in great five-axis turning-milling complex computer numerical control (CNC machine. It is convenient and always only three dimensional (3D graphic parts needed firstly prepared and further more detail used for the commercial CAE. It is desirable to predict a deformed position for the cut tool under external pressure loads in the working process of CNC machine. The linear results for static analysis of stresses, displacements in corresponding to the screw shaft locates at top, medium and bottom positions of the secondary shaft systems are obtained by using the simulation module of SOLIDWORKS®.

  2. Mathematical Modeling and Dynamic Simulation of Metabolic Reaction Systems Using Metabolome Time Series Data

    Directory of Open Access Journals (Sweden)

    Kansuporn eSriyudthsak

    2016-05-01

    Full Text Available The high-throughput acquisition of metabolome data is greatly anticipated for the complete understanding of cellular metabolism in living organisms. A variety of analytical technologies have been developed to acquire large-scale metabolic profiles under different biological or environmental conditions. Time series data are useful for predicting the most likely metabolic pathways because they provide important information regarding the accumulation of metabolites, which implies causal relationships in the metabolic reaction network. Considerable effort has been undertaken to utilize these data for constructing a mathematical model merging system properties and quantitatively characterizing a whole metabolic system in toto. However, there are technical difficulties between benchmarking the provision and utilization of data. Although hundreds of metabolites can be measured, which provide information on the metabolic reaction system, simultaneous measurement of thousands of metabolites is still challenging. In addition, it is nontrivial to logically predict the dynamic behaviors of unmeasurable metabolite concentrations without sufficient information on the metabolic reaction network. Yet, consolidating the advantages of advancements in both metabolomics and mathematical modeling remain to be accomplished. This review outlines the conceptual basis of and recent advances in technologies in both the research fields. It also highlights the potential for constructing a large-scale mathematical model by estimating model parameters from time series metabolome data in order to comprehensively understand metabolism at the systems level.

  3. Mathematical Modeling and Dynamic Simulation of Metabolic Reaction Systems Using Metabolome Time Series Data.

    Science.gov (United States)

    Sriyudthsak, Kansuporn; Shiraishi, Fumihide; Hirai, Masami Yokota

    2016-01-01

    The high-throughput acquisition of metabolome data is greatly anticipated for the complete understanding of cellular metabolism in living organisms. A variety of analytical technologies have been developed to acquire large-scale metabolic profiles under different biological or environmental conditions. Time series data are useful for predicting the most likely metabolic pathways because they provide important information regarding the accumulation of metabolites, which implies causal relationships in the metabolic reaction network. Considerable effort has been undertaken to utilize these data for constructing a mathematical model merging system properties and quantitatively characterizing a whole metabolic system in toto. However, there are technical difficulties between benchmarking the provision and utilization of data. Although, hundreds of metabolites can be measured, which provide information on the metabolic reaction system, simultaneous measurement of thousands of metabolites is still challenging. In addition, it is nontrivial to logically predict the dynamic behaviors of unmeasurable metabolite concentrations without sufficient information on the metabolic reaction network. Yet, consolidating the advantages of advancements in both metabolomics and mathematical modeling remain to be accomplished. This review outlines the conceptual basis of and recent advances in technologies in both the research fields. It also highlights the potential for constructing a large-scale mathematical model by estimating model parameters from time series metabolome data in order to comprehensively understand metabolism at the systems level.

  4. A Development of Automatic Audit System for Written Informed Consent using Machine Learning.

    Science.gov (United States)

    Yamada, Hitomi; Takemura, Tadamasa; Asai, Takahiro; Okamoto, Kazuya; Kuroda, Tomohiro; Kuwata, Shigeki

    2015-01-01

    In Japan, most of all the university and advanced hospitals have implemented both electronic order entry systems and electronic charting. In addition, all medical records are subjected to inspector audit for quality assurance. The record of informed consent (IC) is very important as this provides evidence of consent from the patient or patient's family and health care provider. Therefore, we developed an automatic audit system for a hospital information system (HIS) that is able to evaluate IC automatically using machine learning.

  5. Initial Experience with the Machine Protection System for LHC

    CERN Document Server

    Schmidt, Ruediger; Dehning, Bernd; Ferro-Luzzi, Massimiliano; Goddard, Brennan; Lamont, Mike; Siemko, Andrzej; Uythoven, Jan; Wenninger, Jorg; Zerlauth, Markus

    2010-01-01

    For nominal beam parameters at 7 TeV/c each proton beam with a stored energy of 362 MJ threatens to damage accelerator equipment in case of uncontrolled beam loss. These parameters will only be reached after some years of operation, however, a small fraction of this energy is already sufficient to damage accelerator equipment or experiments. The correct functioning of the machine protection systems is vital during the different operational phases already for initial operation. When operating the complex magnet system, with and without beam, safe operation relies on the protection and interlock systems for the superconducting circuits. For safe injection and transfer of the beams from SPS to LHC, transfer line parameters are monitored, beam absorbers must be in the correct position and the LHC must be ready to accept beam. At the end of a fill and in case of failures beams must be properly extracted onto the dump blocks, for some types of failure within less than few hundred microseconds. Safe operation requir...

  6. A Shear-Wave Seismic System to Look Ahead of a Tunnel Boring Machine

    NARCIS (Netherlands)

    Bharadwaj, Pawan; Drijkoningen, G.G.; Mulder, W.A.; Tscharner, Thomas; Jenneskens, Rob

    2016-01-01

    The Earth’s properties, composition and structure ahead of a tunnel boring machine (TBM) should be mapped for hazard assessment during excavation. We study the use of seismic-exploration techniques for this purpose. We focus on a seismic system for soft soils, where shear waves are better and easier

  7. Emerging Paradigms in Machine Learning

    CERN Document Server

    Jain, Lakhmi; Howlett, Robert

    2013-01-01

    This  book presents fundamental topics and algorithms that form the core of machine learning (ML) research, as well as emerging paradigms in intelligent system design. The  multidisciplinary nature of machine learning makes it a very fascinating and popular area for research.  The book is aiming at students, practitioners and researchers and captures the diversity and richness of the field of machine learning and intelligent systems.  Several chapters are devoted to computational learning models such as granular computing, rough sets and fuzzy sets An account of applications of well-known learning methods in biometrics, computational stylistics, multi-agent systems, spam classification including an extremely well-written survey on Bayesian networks shed light on the strengths and weaknesses of the methods. Practical studies yielding insight into challenging problems such as learning from incomplete and imbalanced data, pattern recognition of stochastic episodic events and on-line mining of non-stationary ...

  8. Metabolism

    Science.gov (United States)

    ... Are More Common in People With Type 1 Diabetes Metabolic Syndrome Your Child's Weight Healthy Eating Endocrine System Blood Test: Basic Metabolic Panel (BMP) Activity: Endocrine System Growth Disorders Diabetes Center Thyroid Disorders Your Endocrine System Movie: Endocrine ...

  9. E-core transverse flux machine with integrated fault detection system

    DEFF Research Database (Denmark)

    Rasmussen, Peter Omand; Runólfsson, Gunnar; Thorsdóttir, Thórunn Ágústa

    2011-01-01

    extent also thermal. Since the E-core transverse flux-machine belongs to the family of the SRMs it has unique properties of intervals without current in the windings. By careful investigation of the voltage and current in these intervals a very simple method to detect single and partial turn short...... circuit faults have been developed. For other types of machines the single and partial turn short circuit is very difficult to deal with and requires normally very comprehensive detection and calculation schemes. The developed detection algorithm combined with the E-core transverse flux machine...

  10. Tool set for distributed real-time machine control

    Science.gov (United States)

    Carrott, Andrew J.; Wright, Christopher D.; West, Andrew A.; Harrison, Robert; Weston, Richard H.

    1997-01-01

    Demands for increased control capabilities require next generation manufacturing machines to comprise intelligent building elements, physically located at the point where the control functionality is required. Networks of modular intelligent controllers are increasingly designed into manufacturing machines and usable standards are slowly emerging. To implement a control system using off-the-shelf intelligent devices from multi-vendor sources requires a number of well defined activities, including (a) the specification and selection of interoperable control system components, (b) device independent application programming and (c) device configuration, management, monitoring and control. This paper briefly discusses the support for the above machine lifecycle activities through the development of an integrated computing environment populated with an extendable software toolset. The toolset supports machine builder activities such as initial control logic specification, logic analysis, machine modeling, mechanical verification, application programming, automatic code generation, simulation/test, version control, distributed run-time support and documentation. The environment itself consists of system management tools and a distributed object-oriented database which provides storage for the outputs from machine lifecycle activities and specific target control solutions.

  11. The criteria for metabolic syndrome and the national health screening and education system in Japan

    Directory of Open Access Journals (Sweden)

    Kazumasa Yamagishi

    2017-01-01

    Full Text Available Two major definitions of metabolic syndrome have been proposed. One focuses on the accumulation of risk factors, a measure used by the American Heart Association (AHA and the National Heart, Lung, and Blood Institute (NHLBI; the other focuses on abdominal obesity, a measure used by the International Diabetes Federation (IDF and the Japanese government. The latter definition takes waist circumference (WC into consideration as an obligatory component, whereas the former does not. In 2009, the IDF, NHLBI, AHA, and other organizations attempted to unify these criteria; as a result, WC is no longer an obligatory component of those systems, while it remains obligatory in the Japanese criteria. In 2008, a new Japanese cardiovascular screening and education system focused on metabolic syndrome was launched. People undergoing screening are classified into three groups according to the presence of abdominal obesity and the number of metabolic risk factors, and receive health educational support from insurers. This system has yielded several beneficial outcomes: the visibility of metabolic syndrome at the population level has drastically improved; preventive measures have been directed toward metabolic syndrome, which is expected to become more prevalent in future generations; and a post-screening education system has been established. However, several problems with the current system have been identified and are under debate. In this review, we discuss topics related to metabolic syndrome, including (1 the Japanese criteria for metabolic syndrome; (2 metabolic syndrome and the universal health screening and education system; and (3 recent debates about Japanese criteria for metabolic syndrome.

  12. The DELPHI distributed information system for exchanging LEP machine related information

    International Nuclear Information System (INIS)

    Doenszelmann, M.; Gaspar, C.

    1994-01-01

    An information management system was designed and implemented to interchange information between the DELPHI experiment at CERN and the monitoring/control system for the LEP (Large Electron Positron Collider) accelerator. This system is distributed and communicates with many different sources and destinations (LEP) using different types of communication. The system itself communicates internally via a communication system based on a publish-and-subscribe mechanism, DIM (Distributed Information Manager). The information gathered by this system is used for on-line as well as off-line data analysis. Therefore it logs the information to a database and makes it available to operators and users via DUI (DELPHI User Interface). The latter was extended to be capable of displaying ''time-evolution'' plots. It also handles a protocol, implemented using a finite state machine, SMI (State Management Interface), for (semi-)automatic running of the Data Acquisition System and the Slow Controls System. ((orig.))

  13. Structural dynamics of turbo-machines

    CERN Document Server

    Rangwala, AS

    2009-01-01

    The book presents a detailed and comprehensive treatment of structural vibration evaluation of turbo-machines. Starting with the fundamentals of the theory of vibration as related to various aspects of rotating machines, the dynamic analysis procedures of a broad spectrum of turbo-machines is covered. An in-depth procedure for analyzing the torsional and flexural oscillations of the components and of the rotor-bearing system is presented. The latest trends in design and analysis are presented, chief among them: Blade and coupled disk-blade mod

  14. Stereoscopic display in a slot machine

    Science.gov (United States)

    Laakso, M.

    2012-03-01

    This paper reports the results of a user trial with a slot machine equipped with a stereoscopic display. The main research question was to find out what kind of added value does stereoscopic 3D (S-3D) bring to slot games? After a thorough literature survey, a novel gaming platform was designed and implemented. Existing multi-game slot machine "Nova" was converted to "3DNova" by replacing the monitor with an S-3D display and converting six original games to S-3D format. To evaluate the system, several 3DNova machines were put available for players for four months. Both qualitative and quantitative analysis was carried out from statistical values, questionnaires and observations. According to the results, people find the S-3D concept interesting but the technology is not optimal yet. Young adults and adults were fascinated by the system, older people were more cautious. Especially the need to wear stereoscopic glasses provide a challenge; ultimate system would probably use autostereoscopic technology. Also the games should be designed to utilize its full power. The main contributions of this paper are lessons learned from creating an S-3D slot machine platform and novel information about human factors related to stereoscopic slot machine gaming.

  15. Expert system for assisting the diagnostic and localisation of breakdowns on the fuel elements loading machine

    International Nuclear Information System (INIS)

    Merlin, J.; Pradal, B.

    1990-01-01

    An expert system is developed in order to minimize the time lost through breakdowns of the fuel loading device. The expert system developed by FRAMATOME uses MAINTEX software. The expert systems MACHA and SEDMAC were designed respectively for use on 1300 MWe and 900 MWe loading machines [fr

  16. Cleaning and can end chamfering special machine MSCS-04

    International Nuclear Information System (INIS)

    Negulescu, D.; Rusu, A.; Dragomir, I.; Turcanu, V.; Bailescu, V.; Burcea, Gh.; Chitu, I.

    2001-01-01

    The MSCS-04 machine executes cleaning and can end chamfering of the CANDU 6 fuel element can through the following technologic chain: - manual positioning of the workpiece in the transporter feeding location; - the transport of the workpiece in front of the cleaning machine and workpiece orientation checking; - automatic loading of the workpiece in the cleaning machine; - bonding the workpiece in the cleaning machine; - cleaning the ends of the workpiece with graphite dust aspiration; - automatic disconnection of the workpiece from the cleaning machine; - automatic unloading of the cleaning machine; - disposal of the workpiece on the transporter in front of cleaning machine; workpiece's transport in front of the chamfering machine; - automatic checking of the workpiece orientation; - automatic loading of the workpiece in the chamfering machine; - axial positioning and bounding of the workpiece in the chamfering machine; chamfering the workpiece's ends with graphite dust and splinter aspiration; - disconnecting the workpiece from the chamfering machine; - automatic unloading of the workpiece from the chamfering machine with splinter blow from the workpiece interior; - workpiece disposal on transporter and the piece transport to the outlet. Details about the technological system, transport system, manipulators, cleaning and chamfering machines are given. Novel elements are highlighted and the technical characteristics are presented

  17. Seeing the wood for the trees: a forest of methods for optimization and omic-network integration in metabolic modelling.

    Science.gov (United States)

    Vijayakumar, Supreeta; Conway, Max; Lió, Pietro; Angione, Claudio

    2017-05-30

    Metabolic modelling has entered a mature phase with dozens of methods and software implementations available to the practitioner and the theoretician. It is not easy for a modeller to be able to see the wood (or the forest) for the trees. Driven by this analogy, we here present a 'forest' of principal methods used for constraint-based modelling in systems biology. This provides a tree-based view of methods available to prospective modellers, also available in interactive version at http://modellingmetabolism.net, where it will be kept updated with new methods after the publication of the present manuscript. Our updated classification of existing methods and tools highlights the most promising in the different branches, with the aim to develop a vision of how existing methods could hybridize and become more complex. We then provide the first hands-on tutorial for multi-objective optimization of metabolic models in R. We finally discuss the implementation of multi-view machine learning approaches in poly-omic integration. Throughout this work, we demonstrate the optimization of trade-offs between multiple metabolic objectives, with a focus on omic data integration through machine learning. We anticipate that the combination of a survey, a perspective on multi-view machine learning and a step-by-step R tutorial should be of interest for both the beginner and the advanced user. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  18. Performance of Color Camera Machine Vision in Automated Furniture Rough Mill Systems

    Science.gov (United States)

    D. Earl Kline; Agus Widoyoko; Janice K. Wiedenbeck; Philip A. Araman

    1998-01-01

    The objective of this study was to evaluate the performance of color camera machine vision for lumber processing in a furniture rough mill. The study used 134 red oak boards to compare the performance of automated gang-rip-first rough mill yield based on a prototype color camera lumber inspection system developed at Virginia Tech with both estimated optimum rough mill...

  19. Methods, systems and apparatus for controlling third harmonic voltage when operating a multi-space machine in an overmodulation region

    Science.gov (United States)

    Perisic, Milun; Kinoshita, Michael H; Ranson, Ray M; Gallegos-Lopez, Gabriel

    2014-06-03

    Methods, system and apparatus are provided for controlling third harmonic voltages when operating a multi-phase machine in an overmodulation region. The multi-phase machine can be, for example, a five-phase machine in a vector controlled motor drive system that includes a five-phase PWM controlled inverter module that drives the five-phase machine. Techniques for overmodulating a reference voltage vector are provided. For example, when the reference voltage vector is determined to be within the overmodulation region, an angle of the reference voltage vector can be modified to generate a reference voltage overmodulation control angle, and a magnitude of the reference voltage vector can be modified, based on the reference voltage overmodulation control angle, to generate a modified magnitude of the reference voltage vector. By modifying the reference voltage vector, voltage command signals that control a five-phase inverter module can be optimized to increase output voltages generated by the five-phase inverter module.

  20. Fuzzy Decision-Making Fuser (FDMF for Integrating Human-Machine Autonomous (HMA Systems with Adaptive Evidence Sources

    Directory of Open Access Journals (Sweden)

    Yu-Ting Liu

    2017-06-01

    Full Text Available A brain-computer interface (BCI creates a direct communication pathway between the human brain and an external device or system. In contrast to patient-oriented BCIs, which are intended to restore inoperative or malfunctioning aspects of the nervous system, a growing number of BCI studies focus on designing auxiliary systems that are intended for everyday use. The goal of building these BCIs is to provide capabilities that augment existing intact physical and mental capabilities. However, a key challenge to BCI research is human variability; factors such as fatigue, inattention, and stress vary both across different individuals and for the same individual over time. If these issues are addressed, autonomous systems may provide additional benefits that enhance system performance and prevent problems introduced by individual human variability. This study proposes a human-machine autonomous (HMA system that simultaneously aggregates human and machine knowledge to recognize targets in a rapid serial visual presentation (RSVP task. The HMA focuses on integrating an RSVP BCI with computer vision techniques in an image-labeling domain. A fuzzy decision-making fuser (FDMF is then applied in the HMA system to provide a natural adaptive framework for evidence-based inference by incorporating an integrated summary of the available evidence (i.e., human and machine decisions and associated uncertainty. Consequently, the HMA system dynamically aggregates decisions involving uncertainties from both human and autonomous agents. The collaborative decisions made by an HMA system can achieve and maintain superior performance more efficiently than either the human or autonomous agents can achieve independently. The experimental results shown in this study suggest that the proposed HMA system with the FDMF can effectively fuse decisions from human brain activities and the computer vision techniques to improve overall performance on the RSVP recognition task. This

  1. Fuzzy Decision-Making Fuser (FDMF) for Integrating Human-Machine Autonomous (HMA) Systems with Adaptive Evidence Sources.

    Science.gov (United States)

    Liu, Yu-Ting; Pal, Nikhil R; Marathe, Amar R; Wang, Yu-Kai; Lin, Chin-Teng

    2017-01-01

    A brain-computer interface (BCI) creates a direct communication pathway between the human brain and an external device or system. In contrast to patient-oriented BCIs, which are intended to restore inoperative or malfunctioning aspects of the nervous system, a growing number of BCI studies focus on designing auxiliary systems that are intended for everyday use. The goal of building these BCIs is to provide capabilities that augment existing intact physical and mental capabilities. However, a key challenge to BCI research is human variability; factors such as fatigue, inattention, and stress vary both across different individuals and for the same individual over time. If these issues are addressed, autonomous systems may provide additional benefits that enhance system performance and prevent problems introduced by individual human variability. This study proposes a human-machine autonomous (HMA) system that simultaneously aggregates human and machine knowledge to recognize targets in a rapid serial visual presentation (RSVP) task. The HMA focuses on integrating an RSVP BCI with computer vision techniques in an image-labeling domain. A fuzzy decision-making fuser (FDMF) is then applied in the HMA system to provide a natural adaptive framework for evidence-based inference by incorporating an integrated summary of the available evidence (i.e., human and machine decisions) and associated uncertainty. Consequently, the HMA system dynamically aggregates decisions involving uncertainties from both human and autonomous agents. The collaborative decisions made by an HMA system can achieve and maintain superior performance more efficiently than either the human or autonomous agents can achieve independently. The experimental results shown in this study suggest that the proposed HMA system with the FDMF can effectively fuse decisions from human brain activities and the computer vision techniques to improve overall performance on the RSVP recognition task. This conclusion

  2. System-level perturbations of cell metabolism using CRISPR/Cas9

    DEFF Research Database (Denmark)

    Jakociunas, Tadas; Jensen, Michael Krogh; Keasling, Jay

    2017-01-01

    CRISPR/Cas9 (clustered regularly interspaced palindromic repeats and the associated protein Cas9) techniques have made genome engineering and transcriptional reprogramming studies more advanced and cost-effective. For metabolic engineering purposes, the CRISPR-based tools have been applied...... previously possible. In this mini-review we highlight recent studies adopting CRISPR/Cas9 for systems-level perturbations and model-guided metabolic engineering....

  3. Considerations upon the Machine Learning Technologies

    Directory of Open Access Journals (Sweden)

    Alin Munteanu

    2006-01-01

    Full Text Available Artificial intelligence offers superior techniques and methods by which problems from diverse domains may find an optimal solution. The Machine Learning technologies refer to the domain of artificial intelligence aiming to develop the techniques allowing the computers to “learn”. Some systems based on Machine Learning technologies tend to eliminate the necessity of the human intelligence while the others adopt a man-machine collaborative approach.

  4. Performance test of the prototype-unit for J-PARC machine protection system

    International Nuclear Information System (INIS)

    Sakaki, Hironao; Nakamura, Naoki; Takahashi, Hiroki; Yoshikawa, Hiroshi

    2004-03-01

    In High Intensity Proton Accelerator Project (J-PARC), the high-power proton beam is accelerated. If the beam in J-PARC is not stopped at a few micro seconds or less, the fatal thermal shock destruction is caused on the surface of accelerating structure, because of the high-power proton beam. To avoid the thermal shock damage, we designed the high-speed machine protection system. And, the prototype unit for the system was produced. This report shows the result of its performance test. (author)

  5. Adaptive Learning Systems: Beyond Teaching Machines

    Science.gov (United States)

    Kara, Nuri; Sevim, Nese

    2013-01-01

    Since 1950s, teaching machines have changed a lot. Today, we have different ideas about how people learn, what instructor should do to help students during their learning process. We have adaptive learning technologies that can create much more student oriented learning environments. The purpose of this article is to present these changes and its…

  6. Frequency Dependent PD-pulse Distortion in Rotating Machines

    DEFF Research Database (Denmark)

    Holbøll, Joachim T.; Henriksen, Mogens

    1996-01-01

    at the machine terminals. The results show a variation of the attenuation of the discharge pulses inside the machine of about 20 dB highest for pulses from the far end, i.e. the neutral point. The capability of exact localization of the discharges in the winding gives a correct measure of the range...... of the current transformer based detection method, when being applied to rotating machines. The results are discussed with regard to the practical application of PD detection systems on rotating machines, particularly considering aspects of range and applicability of systems in the HF ranges...

  7. Inhibited Carnitine Synthesis Causes Systemic Alteration of Nutrient Metabolism in Zebrafish.

    Science.gov (United States)

    Li, Jia-Min; Li, Ling-Yu; Qin, Xuan; Degrace, Pascal; Demizieux, Laurent; Limbu, Samwel M; Wang, Xin; Zhang, Mei-Ling; Li, Dong-Liang; Du, Zhen-Yu

    2018-01-01

    Impaired mitochondrial fatty acid β-oxidation has been correlated with many metabolic syndromes, and the metabolic characteristics of the mammalian models of mitochondrial dysfunction have also been intensively studied. However, the effects of the impaired mitochondrial fatty acid β-oxidation on systemic metabolism in teleost have never been investigated. In the present study, we established a low-carnitine zebrafish model by feeding fish with mildronate as a specific carnitine synthesis inhibitor [0.05% body weight (BW)/d] for 7 weeks, and the systemically changed nutrient metabolism, including carnitine and triglyceride (TG) concentrations, fatty acid (FA) β-oxidation capability, and other molecular and biochemical assays of lipid, glucose, and protein metabolism, were measured. The results indicated that mildronate markedly decreased hepatic carnitine concentrations while it had no effect in muscle. Liver TG concentrations increased by more than 50% in mildronate-treated fish. Mildronate decreased the efficiency of liver mitochondrial β-oxidation, increased the hepatic mRNA expression of genes related to FA β-oxidation and lipolysis, and decreased the expression of lipogenesis genes. Mildronate decreased whole body glycogen content, increased glucose metabolism rate, and upregulated the expression of glucose uptake and glycolysis genes. Mildronate also increased whole body protein content and hepatic mRNA expression of mechanistic target of rapamycin ( mtor ), and decreased the expression of a protein catabolism-related gene. Liver, rather than muscle, was the primary organ targeted by mildronate. In short, mildronate-induced hepatic inhibited carnitine synthesis in zebrafish caused decreased mitochondrial FA β-oxidation efficiency, greater lipid accumulation, and altered glucose and protein metabolism. This reveals the key roles of mitochondrial fatty acid β-oxidation in nutrient metabolism in fish, and this low-carnitine zebrafish model could also be

  8. Inhibited Carnitine Synthesis Causes Systemic Alteration of Nutrient Metabolism in Zebrafish

    Directory of Open Access Journals (Sweden)

    Jia-Min Li

    2018-05-01

    Full Text Available Impaired mitochondrial fatty acid β-oxidation has been correlated with many metabolic syndromes, and the metabolic characteristics of the mammalian models of mitochondrial dysfunction have also been intensively studied. However, the effects of the impaired mitochondrial fatty acid β-oxidation on systemic metabolism in teleost have never been investigated. In the present study, we established a low-carnitine zebrafish model by feeding fish with mildronate as a specific carnitine synthesis inhibitor [0.05% body weight (BW/d] for 7 weeks, and the systemically changed nutrient metabolism, including carnitine and triglyceride (TG concentrations, fatty acid (FA β-oxidation capability, and other molecular and biochemical assays of lipid, glucose, and protein metabolism, were measured. The results indicated that mildronate markedly decreased hepatic carnitine concentrations while it had no effect in muscle. Liver TG concentrations increased by more than 50% in mildronate-treated fish. Mildronate decreased the efficiency of liver mitochondrial β-oxidation, increased the hepatic mRNA expression of genes related to FA β-oxidation and lipolysis, and decreased the expression of lipogenesis genes. Mildronate decreased whole body glycogen content, increased glucose metabolism rate, and upregulated the expression of glucose uptake and glycolysis genes. Mildronate also increased whole body protein content and hepatic mRNA expression of mechanistic target of rapamycin (mtor, and decreased the expression of a protein catabolism-related gene. Liver, rather than muscle, was the primary organ targeted by mildronate. In short, mildronate-induced hepatic inhibited carnitine synthesis in zebrafish caused decreased mitochondrial FA β-oxidation efficiency, greater lipid accumulation, and altered glucose and protein metabolism. This reveals the key roles of mitochondrial fatty acid β-oxidation in nutrient metabolism in fish, and this low-carnitine zebrafish model

  9. The nervous system and metabolic dysregulation: emerging evidence converges on ketogenic diet therapy

    Directory of Open Access Journals (Sweden)

    David N. Ruskin

    2012-03-01

    Full Text Available A link between metabolism and brain function is clear. Since ancient times, epileptic seizures were noted as treatable with fasting, and historical observations of the therapeutic benefits of fasting on epilepsy were confirmed nearly 100 years ago. Shortly thereafter a high-fat, low-carbohydrate ketogenic diet debuted as a therapy to reduce seizures. This strict regimen could mimic the metabolic effects of fasting while allowing adequate caloric intake for ongoing energy demands. Today, ketogenic diet therapy, which forces predominantly ketone-based rather than glucose-based metabolism, is now well-established as highly successful in reducing seizures. More recently, cellular metabolic dysfunction in the nervous system has been recognized as existing side-by-side with nervous system disorders - although often with much less obvious cause-and-effect as the relationship between fasting and seizures. Rekindled interest in metabolic and dietary therapies for brain disorders complements new insight into their mechanisms and broader implications. Here we describe the emerging relationship between a ketogenic diet and adenosine as a way to reset brain metabolism and neuronal activity and disrupt a cycle of dysfunction. We also provide an overview of the effects of a ketogenic diet on cognition and recent data on the effects of a ketogenic diet on pain, and explore the relative time course quantified among hallmark metabolic changes, altered neuron function and altered animal behavior assessed after diet administration. We predict continued applications of metabolic therapies in treating dysfunction including and beyond the nervous system.

  10. The Nervous System and Metabolic Dysregulation: Emerging Evidence Converges on Ketogenic Diet Therapy

    Science.gov (United States)

    Ruskin, David N.; Masino, Susan A.

    2012-01-01

    A link between metabolism and brain function is clear. Since ancient times, epileptic seizures were noted as treatable with fasting, and historical observations of the therapeutic benefits of fasting on epilepsy were confirmed nearly 100 years ago. Shortly thereafter a high fat, low-carbohydrate ketogenic diet (KD) debuted as a therapy to reduce seizures. This strict regimen could mimic the metabolic effects of fasting while allowing adequate caloric intake for ongoing energy demands. Today, KD therapy, which forces predominantly ketone-based rather than glucose-based metabolism, is now well-established as highly successful in reducing seizures. Cellular metabolic dysfunction in the nervous system has been recognized as existing side-by-side with nervous system disorders – although often with much less obvious cause-and-effect as the relationship between fasting and seizures. Rekindled interest in metabolic and dietary therapies for brain disorders complements new insight into their mechanisms and broader implications. Here we describe the emerging relationship between a KD and adenosine as a way to reset brain metabolism and neuronal activity and disrupt a cycle of dysfunction. We also provide an overview of the effects of a KD on cognition and recent data on the effects of a KD on pain, and explore the relative time course quantified among hallmark metabolic changes, altered neuron function and altered animal behavior assessed after diet administration. We predict continued applications of metabolic therapies in treating dysfunction including and beyond the nervous system. PMID:22470316

  11. Introducing Stable Radicals into Molecular Machines.

    Science.gov (United States)

    Wang, Yuping; Frasconi, Marco; Stoddart, J Fraser

    2017-09-27

    Ever since their discovery, stable organic radicals have received considerable attention from chemists because of their unique optical, electronic, and magnetic properties. Currently, one of the most appealing challenges for the chemical community is to develop sophisticated artificial molecular machines that can do work by consuming external energy, after the manner of motor proteins. In this context, radical-pairing interactions are important in addressing the challenge: they not only provide supramolecular assistance in the synthesis of molecular machines but also open the door to developing multifunctional systems relying on the various properties of the radical species. In this Outlook, by taking the radical cationic state of 1,1'-dialkyl-4,4'-bipyridinium (BIPY •+ ) as an example, we highlight our research on the art and science of introducing radical-pairing interactions into functional systems, from prototypical molecular switches to complex molecular machines, followed by a discussion of the (i) limitations of the current systems and (ii) future research directions for designing BIPY •+ -based molecular machines with useful functions.

  12. Analysis on machine tool systems using spindle vibration monitoring for automatic tool changer

    OpenAIRE

    Shang-Liang Chen; Yin-Ting Cheng; Chin-Fa Su

    2015-01-01

    Recently, the intelligent systems of technology have become one of the major items in the development of machine tools. One crucial technology is the machinery status monitoring function, which is required for abnormal warnings and the improvement of cutting efficiency. During processing, the mobility act of the spindle unit determines the most frequent and important part such as automatic tool changer. The vibration detection system includes the development of hardware and software, such as ...

  13. The development of management information systems for running machines at full potential

    Energy Technology Data Exchange (ETDEWEB)

    Steel, W.T.

    1988-08-01

    Statistics show that in the UK in the month of March 1988, coal face machines ran on average 114 minutes per machine shift. The average for the financial year 1987/88 was 110 minutes, which was 34% of available time. Since January 1986, machine available time has been held at around 320 min. During the same period, however, machine running time has remained static also even though several hundred million pounds has been invested in heavy duty equipment, and the number of retreat faces as a percentage of the total number in operation has increased. Our machines generally are operating at less than 50% of potential, potential being defined as the output produced if the machines operate at the expected rate, and stop only for the expected turn-round time. These statistics are derived from method study standards, which are perhaps open to challenge, but on these norms, one extra minute of machine running time per machine shift throughout the industry in the year 1987/88 would have produced about 26 million pounds of extra revenue. Although the statistics are generalisations, they demonstrate not only the problem to which the industry must address itself if it is to be competitive but also the scope which is available for improvements. 5 figs.

  14. Man machine interface and its implementation

    International Nuclear Information System (INIS)

    Hills, B.G.; Boettcher, D.B.; Reed, R.

    1992-01-01

    Sizewell B is the latest nuclear power station to be constructed in the United Kingdom: its Man-Machine Interfaces are therefore, by definition, the state-of-the-art. This paper discusses the principal Man-Machine Interfaces used in the operation of the station, and the systems that implement them. The Man-Machine Interface facilities discussed are: in the Main Control Room, which is used for normal operation and shutdown of the plant: in the Auxiliary Shutdown Room, which allows shutdown of the reactor if evacuation of the main Control Room is necessary: and in the Technical Support Centre, which is used for remote monitoring of the plant. The Man-Machine Interfaces that are described are parts of a station-wide group of interlinked computer systems called the Data Processing and Control System. This system collects data from the plant and displays it to the operators via discrete devices and on graphical computer displays. It also acquires control inputs from the operators via switches, which are then used to provide remote manual control, modulating control and sequence control. The computer system that handles the plant process data and alarm information displays uses a windowing interface with keyboard and trackerball navigation to allow easy retrieval and viewing of information. It is this system that is the main topic of this paper. (author)

  15. Discrete time analysis of a repairable machine

    OpenAIRE

    Alfa, Attahiru Sule; Castro, I. T.

    2002-01-01

    We consider, in discrete time, a single machine system that operates for a period of time represented by a general distribution. This machine is subject to failures during operations and the occurrence of these failures depends on how many times the machine has previously failed. Some failures are repairable and the repair times may or may not depend on the number of times the machine was previously repaired. Repair times also have a general distribution. The operating times...

  16. Machine learning techniques applied to system characterization and equalization

    DEFF Research Database (Denmark)

    Zibar, Darko; Thrane, Jakob; Wass, Jesper

    2016-01-01

    Linear signal processing algorithms are effective in combating linear fibre channel impairments. We demonstrate the ability of machine learning algorithms to combat nonlinear fibre channel impairments and perform parameter extraction from directly detected signals.......Linear signal processing algorithms are effective in combating linear fibre channel impairments. We demonstrate the ability of machine learning algorithms to combat nonlinear fibre channel impairments and perform parameter extraction from directly detected signals....

  17. Plant metabolic modeling: achieving new insight into metabolism and metabolic engineering.

    Science.gov (United States)

    Baghalian, Kambiz; Hajirezaei, Mohammad-Reza; Schreiber, Falk

    2014-10-01

    Models are used to represent aspects of the real world for specific purposes, and mathematical models have opened up new approaches in studying the behavior and complexity of biological systems. However, modeling is often time-consuming and requires significant computational resources for data development, data analysis, and simulation. Computational modeling has been successfully applied as an aid for metabolic engineering in microorganisms. But such model-based approaches have only recently been extended to plant metabolic engineering, mainly due to greater pathway complexity in plants and their highly compartmentalized cellular structure. Recent progress in plant systems biology and bioinformatics has begun to disentangle this complexity and facilitate the creation of efficient plant metabolic models. This review highlights several aspects of plant metabolic modeling in the context of understanding, predicting and modifying complex plant metabolism. We discuss opportunities for engineering photosynthetic carbon metabolism, sucrose synthesis, and the tricarboxylic acid cycle in leaves and oil synthesis in seeds and the application of metabolic modeling to the study of plant acclimation to the environment. The aim of the review is to offer a current perspective for plant biologists without requiring specialized knowledge of bioinformatics or systems biology. © 2014 American Society of Plant Biologists. All rights reserved.

  18. Dynamic analysis and vibration testing of CFRP drive-line system used in heavy-duty machine tool

    Science.gov (United States)

    Yang, Mo; Gui, Lin; Hu, Yefa; Ding, Guoping; Song, Chunsheng

    2018-03-01

    Low critical rotary speed and large vibration in the metal drive-line system of heavy-duty machine tool affect the machining precision seriously. Replacing metal drive-line with the CFRP drive-line can effectively solve this problem. Based on the composite laminated theory and the transfer matrix method (TMM), this paper puts forward a modified TMM to analyze dynamic characteristics of CFRP drive-line system. With this modified TMM, the CFRP drive-line of a heavy vertical miller is analyzed. And the finite element modal analysis model of the shafting is established. The results of the modified TMM and finite element analysis (FEA) show that the modified TMM can effectively predict the critical rotary speed of CFRP drive-line. And the critical rotary speed of CFRP drive-line is 20% higher than that of the original metal drive-line. Then, the vibration of the CFRP and the metal drive-line were tested. The test results show that application of the CFRP drive shaft in the drive-line can effectively reduce the vibration of the heavy-duty machine tool.

  19. Research on the tool holder mode in high speed machining

    Science.gov (United States)

    Zhenyu, Zhao; Yongquan, Zhou; Houming, Zhou; Xiaomei, Xu; Haibin, Xiao

    2018-03-01

    High speed machining technology can improve the processing efficiency and precision, but also reduce the processing cost. Therefore, the technology is widely regarded in the industry. With the extensive application of high-speed machining technology, high-speed tool system has higher and higher requirements on the tool chuck. At present, in high speed precision machining, several new kinds of clip heads are as long as there are heat shrinkage tool-holder, high-precision spring chuck, hydraulic tool-holder, and the three-rib deformation chuck. Among them, the heat shrinkage tool-holder has the advantages of high precision, high clamping force, high bending rigidity and dynamic balance, etc., which are widely used. Therefore, it is of great significance to research the new requirements of the machining tool system. In order to adapt to the requirement of high speed machining precision machining technology, this paper expounds the common tool holder technology of high precision machining, and proposes how to select correctly tool clamping system in practice. The characteristics and existing problems are analyzed in the tool clamping system.

  20. A computer architecture for intelligent machines

    Science.gov (United States)

    Lefebvre, D. R.; Saridis, G. N.

    1992-01-01

    The theory of intelligent machines proposes a hierarchical organization for the functions of an autonomous robot based on the principle of increasing precision with decreasing intelligence. An analytic formulation of this theory using information-theoretic measures of uncertainty for each level of the intelligent machine has been developed. The authors present a computer architecture that implements the lower two levels of the intelligent machine. The architecture supports an event-driven programming paradigm that is independent of the underlying computer architecture and operating system. Execution-level controllers for motion and vision systems are briefly addressed, as well as the Petri net transducer software used to implement coordination-level functions. A case study illustrates how this computer architecture integrates real-time and higher-level control of manipulator and vision systems.