Smart-grid Investments, Regulation and Organization

DEFF Research Database (Denmark)

Agrell, Per J.; Bogetoft, Peter; Mikkers, Misja

2013-01-01

Grid infrastructure managers worldwide are facing demands for reinvestments in new assets with higher on-grid and off-grid functionality in order to meet new environmental targets. The roles of the current actors will change as the vertical interfaces between regulated and unregulated tasks become...... blurred. In this paper, we characterize some of the effects of new asset investments policy on the network tasks, assets and costs and contrast this with the assumptions of the current economic network regulation. To provide structure, we present a model of investment provision under regulation between...

Technical committee meeting 'to produce draft topical documents on provisions for the application of the regulations for the safe transport of radioactive material'. Chairman's report

International Nuclear Information System (INIS)

Baekelandt, Luc

2000-01-01

In 1996 a new Edition of the IAEA Transport Regulations was published as ST-1. These Regulations have been re-issued in 2000 as TS-R-1 (ST-1, Revised) with only minor editorial changes. These Regulations have not entered into force yet (at the time of this publication) through their incorporation in the legally binding modal regulations; currently it is foreseen that the modal requirements will enter into force during 2001, with transitional periods ranging from zero to twelve months. Nevertheless, a revision process has been started that must lead to a new edition of the regulations in 2003, becoming actually effective in 2005. This document contains the conclusions and recommendations made by the Technical Committee at the meeting. It also contains the reports of the working groups, outlines of draft TECDOCs on radiation protection programmes and on transition from SS 6 to TS-R-1

Labelling of electronic cigarettes: regulations and current practice.

Science.gov (United States)

Buonocore, Federico; Marques Gomes, Ana C N; Nabhani-Gebara, Shereen; Barton, Stephen J; Calabrese, Gianpiero

2017-01-01

Over the past decade e-cigarettes have established themselves in the global market. E-cigarettes triggered much interest in relation to their content and efficacy as smoking cessation tools, but less attention has been paid to users and environmental safety warnings and guidance. Several regulations have been introduced to promote their safe handling and disposal. From May 2016, liquids and cartridges will be regulated by European Community Directives (ECDs) 2001/83/EC and 93/42/EEC, or 2014/40/EU if marketed as tobacco-related products. Currently, manufacturers and distributors must abide by the Chemical (Hazard Information and Packaging for Supply) Regulations 2009 (CHIP) or Classification, Labelling and Packaging Regulations (CLP), the latter replacing CHIP in June 2015. In this work, the compliance of marketed e-liquids and e-cigarettes with current European Union and UK legislations is assessed. E-liquids and e-cigarettes (21 and 9 brands, respectively) were evaluated. Evidence of non-compliance was found in relation to the CHIP/CLP toxic (13%) and environmental (37%) pictograms, tactile warning (23%), nominal amount of solution (30%), supplier contact telephone number and address (40%). None of the evaluated e-cigarettes displayed information on the correct disposal/recycling of batteries in line with the ECD 2006/66/EC. More stringent enforcement of regulations is needed to ensure not only the user's safety and awareness, but also the safeguarding of the environment. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Review of the current state of UAV regulations

NARCIS (Netherlands)

Stöcker, Elvira Claudia; Bennett, Rohan; Nex, Francesco; Gerke, Markus; Zevenbergen, Jaap

2017-01-01

UAVs-unmanned aerial vehicles-facilitate data acquisition at temporal and spatial scales that still remain unachievable for traditional remote sensing platforms. However, current legal frameworks that regulate UAVs present significant barriers to research and development. To highlight the

Design of Current-Controller with PR-regulator for LCL-Filter Based Grid-Connected Converter

DEFF Research Database (Denmark)

Zeng, Guohong; Rasmussen, Tonny Wederberg

2010-01-01

In the application of LCL-filter based converters, the structure and parameters of current-controller is very important for the system stability and output current quality. This paper presents a filter-capacitor current feedback control scheme for grid-connected converter. The controller...... is consisted of a proportional-resonance regulator and a proportional regulator. Unlike the existing control strategy with unit capacitor current feedback, the proposed method applies the proportional regulator to the feedback path, which can decouple these two regulators, and simplify the tuning process...... of the control strategy and the proposed current controller design method are verified by the simulation results of a 50kVA grid-connected inverter....

Meeting summary of the second CSNI specialist meeting on simulators and plant analyzers - Current Issues in Nuclear Power Plant Simulation

International Nuclear Information System (INIS)

1998-01-01

The Second CSNI Specialist Meeting on Simulators and Plant Analyzers: Current Issues in Nuclear Power Plant Simulation was held in Espoo, Finland, from September 29 through October 2, 1997. It was organised by CSNI Principal Working Group on Coolant System Behaviour (PWG2), Task Group on Thermal Hydraulic Applications (TG-THA), in co-operation with Technical Research Centre of Finland. The meeting in Espoo attracted some 90 participants from 17 countries. A total of 49 invited papers were presented in the meeting in addition to 7 simulator system demonstrations. Ample time was reserved for the presentations and informal discussions during the four meeting days. The previous meeting held in Lappeenranta, Finland, in 1992 collected some 85 participants from 12 countries, presenting a total of 40 papers. The meeting was structured into 6 sessions covering the important aspects of development and use of simulators and plant analyzers: Session I: New objectives, Requirements and Concepts. This session covered the progress experienced since the 1. simulator meeting and tried to address the changing role of simulators based on the changes in users' needs and developing possibilities. Session II: Trends in Simulation Technology. This session was reserved for studying the current trends in the simulation technology: software environments, visualisation, simulator configuration tools, programming languages and computer systems. Session III: Training and human factor studies using simulators. This session was created for studying the status of different uses of simulators such as educational simulators, human factor studies and integrated safety assessment in addition to traditional training. Regarding to the severe accidents, a question was raised whether the simulator use should be for training or education. Session IV: Modelling techniques. The session on modelling techniques was included to cover recent developments in the modelling techniques applicable to training

On-line monitoring of base current and forward emitter current gain of the voltage regulator's serial pnp transistor in a radiation environment

Directory of Open Access Journals (Sweden)

Vukić Vladimir Đ.

2012-01-01

Full Text Available A method of on-line monitoring of the low-dropout voltage regulator's operation in a radiation environment is developed in this paper. The method had to enable detection of the circuit's degradation during exploitation, without terminating its operation in an ionizing radiation field. Moreover, it had to enable automatic measurement and data collection, as well as the detection of any considerable degradation, well before the monitored voltage regulator's malfunction. The principal parameters of the voltage regulator's operation that were monitored were the serial pnp transistor's base current and the forward emitter current gain. These parameters were procured indirectly, from the data on the voltage regulator's load and quiescent currents. Since the internal consumption current in moderately and heavily loaded devices was used, the quiescent current of a negligibly loaded voltage regulator of the same type served as a reference. Results acquired by on-line monitoring demonstrated marked agreement with the results acquired from examinations of the voltage regulator's maximum output current and minimum dropout voltage in a radiation environment. The results were particularly consistent in tests with heavily loaded devices. Results obtained for moderately loaded voltage regulators and the risks accompanying the application of the presented method, were also analyzed.

Review of the Current State of UAV Regulations

Directory of Open Access Journals (Sweden)

Claudia Stöcker

2017-05-01

Full Text Available UAVs—unmanned aerial vehicles—facilitate data acquisition at temporal and spatial scales that still remain unachievable for traditional remote sensing platforms. However, current legal frameworks that regulate UAVs present significant barriers to research and development. To highlight the importance, impact, and diversity of UAV regulations, this paper provides an exploratory investigation of UAV regulations on the global scale. For this, the methodological approach consists of a research synthesis of UAV regulations, including a thorough literature review and a comparative analysis of national regulatory frameworks. Similarities and contrasting elements in the various national UAV regulations are explored including their statuses from the perspectives of past, present, and future trends. Since the early 2000s, countries have gradually established national legal frameworks. Although all UAV regulations have one common goal—minimizing the risks to other airspace users and to both people and property on the ground—the results reveal distinct variations in all the compared variables. Furthermore, besides the clear presence of legal frameworks, market forces such as industry design standards and reliable information about UAVs as public goods are expected to shape future developments.

Meeting the International Health Regulations (2005) surveillance core capacity requirements at the subnational level in Europe

DEFF Research Database (Denmark)

Ziemann, Alexandra; Rosenkötter, Nicole; Riesgo, Luis Garcia-Castrillo

2015-01-01

BACKGROUND: The revised World Health Organization's International Health Regulations (2005) request a timely and all-hazard approach towards surveillance, especially at the subnational level. We discuss three questions of syndromic surveillance application in the European context for assessing...... public health emergencies of international concern: (i) can syndromic surveillance support countries, especially the subnational level, to meet the International Health Regulations (2005) core surveillance capacity requirements, (ii) are European syndromic surveillance systems comparable to enable cross...... effect of different types of public health emergencies in a timely manner as required by the International Health Regulations (2005)....

Audit Risk Assessment in the Light of Current European Regulations

OpenAIRE

Ciprian-Costel Munteanu

2015-01-01

Recent European reforms on audit regulations have been motivated by efforts to increase audit quality, functioning and performance. We believe the adoption of Directive 2014/56 and Regulation 537/2014 strengthened the role of independent audit and risk committees, which will positively contribute towards audit quality. This paper aims to critically assess the status quo of audit risk assessment in current European standards and regulations, by conducting a theoretical analysis of different as...

Current regulator for the stabilization of an electrostatic Van de Graaff generator

International Nuclear Information System (INIS)

Gabet, A.; Taieb, J.

1953-01-01

In a previous report (CEA report number 46) we described a current regulator destined to enslave the current of charge of the strap of a model of Van de Graaff. We will now describe the regulator destined to the 5 MeV Van de Graaff built in the Nuclear center of Saclay. (author) [fr

Regulated-current dc power supply for gaseous-discharge lamps

Science.gov (United States)

Freeman, W.; Huguenin, D.

1970-01-01

Controlled current source having a high output resistance feeds continuous-flow hydrogen lamps in vacuum-ultraviolet photometric equipment. The power supply, also used with low-pressure sealed lamps, has a short recovery time and smooth regulation without overshoot.

75 FR 10505 - Office of Apprenticeship, Notice of Town Hall Meeting on Federal Regulations for Equal Employment...

Science.gov (United States)

2010-03-08

... interested individuals an opportunity to provide feedback on and suggestions for revising the current... stakeholder meetings no later than three business days prior to the meeting date. DATES: The town hall... inform the development of the NPRM, DOL is interested in receiving feedback from stakeholders on the...

Pacemaker neuron and network oscillations depend on a neuromodulator-regulated linear current

Directory of Open Access Journals (Sweden)

Shunbing Zhao

2010-05-01

Full Text Available Linear leak currents have been implicated in the regulation of neuronal excitability, generation of neuronal and network oscillations, and network state transitions. Yet, few studies have directly tested the dependence of network oscillations on leak currents or explored the role of leak currents on network activity. In the oscillatory pyloric network of decapod crustaceans neuromodulatory inputs are necessary for pacemaker activity. A large subset of neuromodulators is known to activate a single voltage-gated inward current IMI, which has been shown to regulate the rhythmic activity of the network and its pacemaker neurons. Using the dynamic clamp technique, we show that the crucial component of IMI for the generation of oscillatory activity is only a close-to-linear portion of the current-voltage relationship. The nature of this conductance is such that the presence or the absence of neuromodulators effectively regulates the amount of leak current and the input resistance in the pacemaker neurons. When deprived of neuromodulatory inputs, pyloric oscillations are disrupted; yet, a linear reduction of the total conductance in a single neuron within the pacemaker group recovers not only the pacemaker activity in that neuron, but also leads to a recovery of oscillations in the entire pyloric network. The recovered activity produces proper frequency and phasing that is similar to that induced by neuromodulators. These results show that the passive properties of pacemaker neurons can significantly affect their capacity to generate and regulate the oscillatory activity of an entire network, and that this feature is exploited by neuromodulatory inputs.

29 CFR 102.138 - Definition of meeting.

Science.gov (United States)

2010-07-01

... 29 Labor 2 2010-07-01 2010-07-01 false Definition of meeting. 102.138 Section 102.138 Labor Regulations Relating to Labor NATIONAL LABOR RELATIONS BOARD RULES AND REGULATIONS, SERIES 8 Open Meetings § 102.138 Definition of meeting. For purposes of this subpart, meeting shall mean the deliberations of...

A small potassium current in AgRP/NPY neurons regulates feeding behavior and enery metabolism

Science.gov (United States)

Neurons that co-express agouti-related peptide (AgRP) and neuropeptide Y (NPY) are indispensable for normal feeding behavior. Firing activities of AgRP/NPY neurons are dynamically regulated by energy status and coordinate appropriate feeding behavior to meet nutritional demands. However, intrinsic m...

Meeting the new BSS regulations: what are our strategies?

International Nuclear Information System (INIS)

Mohd Yusof Mohd Ali

2003-01-01

Industrial radiography is a widely known technique of non-destructive testing making use of penetrating ionizing radiation as a means of unfolding information of the subject being tested. It is an accepted practice recognized by industries worldwide. While taking advantage of penetrating nature of the radiation, it is a fact that the radiation can also be harmful to a radiographer and public if a radiation source used is not handled in a proper way and good working practice (GWP) is not observed. Such anticipated hazardous nature of the practice is confirmed by occupational exposure records of industrial radiographers kept by MINT SSDL for the last 15 years, which consistently show high annual dose received by these workers (2 to 43 times higher) as compared to workers involved in other practices. This is not a healthy trend especially in the light of new requirements of Basic Safety Standards (BSS) regulations recommended by IAEA and soon to be adopted by AELB, which allow for much stricter dose limits than before and introduction of new concepts and aspects of radiation protection. This paper highlights the situation of occupational exposure of industrial radiographers in Malaysia and a comparison is made with the experience of some of its counterparts in other countries. It also presents some pertinent points of the new BSS regulations that may cause serious implications to the industrial radiographic practices and some points to be considered as strategies to meet these new requirements. (Author)

50 CFR 453.05 - Committee meetings.

Science.gov (United States)

2010-10-01

... OF COMMERCE); ENDANGERED SPECIES COMMITTEE REGULATIONS ENDANGERED SPECIES EXEMPTION PROCESS ENDANGERED SPECIES COMMITTEE § 453.05 Committee meetings. (a) The committee shall meet at the call of the... Wildlife and Fisheries JOINT REGULATIONS (UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE...

78 FR 17993 - Defense Trade Advisory Group; Notice of Open Meeting

Science.gov (United States)

2013-03-25

... policies, regulations, and technical issues affecting defense trade. The purpose of the meeting will be to... discussed: review of the current definitions of technical data, as well as the control language applied in... statement to the committee in writing. As seating is limited to 125 persons, those wishing to attend the...

Planned and proposed pipeline regulations

International Nuclear Information System (INIS)

De Leon, C.

1992-01-01

The Research and Special Programs Administration administers the Natural Gas Pipeline Safety Act of 1968 (NGPSA) and the Hazardous Liquid Pipeline Safety Act of 1979 (HLPSA). The RSPA issues and enforces design, construction, operation and maintenance regulations for natural gas pipelines and hazardous liquid pipelines. This paper discusses a number of proposed and pending safety regulations and legislative initiatives currently being considered by the RSPA and the US Congress. Some new regulations have been enacted. The next few years will see a great deal of regulatory activity regarding natural gas and hazardous liquid pipelines, much of it resulting from legislative requirements. The office of Pipeline Safety is currently conducting a study to streamline its operations. This study is analyzing the office's business, social and technical operations with the goal of improving overall efficiency, effectiveness, productivity and job satisfaction to meet the challenges of the future

Current state and trend of radiation regulation system in Japan

International Nuclear Information System (INIS)

Yonehara, Hidenori

2004-01-01

Japanese regulation system for safety against radiation essentially started from 'Atomic Energy Basic Law' enacted in 1955 and 'Law Concerning Prevention of Radiation Hazards due to Radioisotopes, etc' enacted in 1957, has been regarded as a central rule for radiation protection and safety. Related laws and regulations have been enacted together with their revision. Radiation Council, established in the Science and Technology Agency in 1962 and now belonging to the Ministry of Education, Culture, Sports, Science and Technology, has deliberated basically on International Commission of Radiological Protection (ICRP) statements for legal revision and has set up working groups for current problems. Activities of the groups have concerned ICRP Publication 60 (1990) and later related publications for incorporating the principle into laws as to concepts of dose limits, effective dose, and then of exemption and exclusion. International status of the Japanese regulation, problems and tasks in the regulation are also commented. (N.I.)

High-voltage integrated linear regulator with current sinking capabilities for portable ultrasound scanners

DEFF Research Database (Denmark)

Pausas, Guifre Vendrell; Llimos Muntal, Pere; Jørgensen, Ivan Harald Holger

2017-01-01

This paper presents a high-voltage integrated regulator capable of sinking current for driving pulse-triggered level shifters in drivers for ultrasound applications. The regulator utilizes a new topology with a feedback loop and a current sinking circuit to satisfy the requirements of the portable....... The proposed design has been implemented in high-voltage 0.18 μm process whithin an area of 0.11 mm2 and it is suitable for system-on-chip integration due to its low component count and the fully integrated design....

A 1.8 V LDO voltage regulator with foldback current limit and thermal protection

International Nuclear Information System (INIS)

Liu Zhiming; Fu Zhongqian; Huang Lu; Xi Tianzuo

2009-01-01

This paper introduces the design of a l.8 V low dropout voltage regulator (LDO) and a foldback current limit circuit which limits the output current to 3 mA when load over-current occurs. The LDO was implemented in a 0.18 μm CMOS technology. The measured result reveals that the LDO's power supply rejection (PSR) is about -58 dB and -54 dB at 20 Hz and 1 kHz respectively, the response time is 4 μs and the quiescent current is 20 μA. The designed LDO regulator can work with a supply voltage down to 2.0 V with a drop-out voltage of 200 mV at a maximum load current of 240 mA. (semiconductor integrated circuits)

Online and Off-line Visualization of Meeting Information and Meeting Support

NARCIS (Netherlands)

Nijholt, Antinus; Rienks, R.J.; Zwiers, Jakob; Reidsma, Dennis

2006-01-01

In current meeting research we see modest attempts to visualize the information that has been obtained by either capturing and probably more importantly by interpreting the activities that take place during a meeting. The meetings being considered take place in smart meeting rooms. Cameras,

Online and Off-line Visualization of Meeting Information and Meeting Support

NARCIS (Netherlands)

Nijholt, Antinus; Seah, H.S.; Rienks, R.J.; Zwiers, Jakob; Reidsma, Dennis

2006-01-01

In current meeting research we see modest attempts to visualize the information that has been obtained by either capturing and, probably more importantly, by interpreting the activities that take place during a meeting. The meetings being considered take place in smart meeting rooms. Cameras,

Strengthening health professions regulation in Cambodia: a rapid assessment.

Science.gov (United States)

Clarke, David; Duke, Jan; Wuliji, Tana; Smith, Alyson; Phuong, Keat; San, Un

2016-03-10

This paper describes a rapid assessment of Cambodia's current system for regulating its health professions. The assessment forms part of a co-design process to set strategic priorities for strengthening health profession regulation to improve the quality and safety of health services. A health system approach for strengthening health professions' regulation is underway and aims to support the Government of Cambodia's plans for scaling up its health workforce, improving health services' safety and quality, and meeting its Association of South East Asian Nations (ASEAN) obligations to facilitate trade in health care services. The assessment used a mixed methods approach including: A desktop review of key laws, plans, reports and other documents relating to the regulation of the health professions in Cambodia (medicine, dentistry, midwifery, nursing and pharmacy); Key informant interviews with stakeholders in Cambodia (The term "stakeholders" refers to government officials, people working on health professional regulation, people working for the various health worker training institutions and health workers at the national and provincial level); Surveys and questionnaires to assess Cambodian stakeholder knowledge of regulation; Self-assessments by members of the five Cambodian regulatory councils regarding key capacities and activities of high-performing regulatory bodies; and A rapid literature review to identify: The key functions of health professional regulation; The key issues affecting the Cambodian health sector (including relevant developments in the wider ASEAN region); and "Smart" health profession regulation practices of possible relevance to Cambodia. We found that the current regulatory system only partially meets Cambodia's needs. A number of key regulatory functions are being performed, but overall, the current system was not designed with Cambodia's specific needs in mind. The existing system is also overly complex, with considerable duplication and

Current control loop design and analysis based on resonant regulators for microgrid applications

DEFF Research Database (Denmark)

Federico, de Bosio; Pastorelli, Michelle; de Sousa Ribeiro, Luiz Antonio

2015-01-01

Voltage and current control loops play an important role in the performance of microgrids employing power electronics voltage source inverters. Correct design of feedback loops is essential for the proper operation of these systems. This paper analyzes the influence of state feedback cross......-coupling in the design of resonant regulators for inner current loops in power converters operating in standalone microgrids. It is also demonstrated that the effect of state feedback cross-coupling degrades the performance of the control loops by increasing the steady-state error. Different resonant regulators...

Use of PSA in the regulatory process. Report of the specialist's meeting. Working material

International Nuclear Information System (INIS)

1994-01-01

The objective of this meeting was to focus on the role of the regulator in relation to PSA, to give a picture of the present status, and near term plans, of the requirements placed on licensees and of the uses, formal and informal, made of PSA in regulatory decision making. One such use, in which there is currently much interest, is known as Risk-Based Regulation. This term has various connotations but essentially refers to a more flexible and efficient application of Technical Specifications in the interests of gains in both economy and safety. The position in many countries is one of change in the use of PSA by regulators, and hence any report can only give a snapshot in time. It has to be noted that a number of countries, with important nuclear power programmes, were not represented at the meeting, and so the overall picture is not as comprehensive as might have been hoped. The field of the discussion in the meeting was divided into three areas, progressed in three working groups, namely: Regulatory requirements related to PSA, Regulatory uses of PSA, and Risk-Based Regulation. The outcomes are covered in the next three sections. The fifth section of this report gives the overall conclusions of the meeting and the final section makes some recommendations for future IAEA activities in these areas. Refs, figs, tabs

A 1.8 V LDO voltage regulator with foldback current limit and thermal protection

Energy Technology Data Exchange (ETDEWEB)

Liu Zhiming; Fu Zhongqian; Huang Lu; Xi Tianzuo, E-mail: zml1985@mail.ustc.edu.c [Department of Electronic Science and Technology, University of Science and Technology of China, Hefei 230027 (China)

2009-08-15

This paper introduces the design of a l.8 V low dropout voltage regulator (LDO) and a foldback current limit circuit which limits the output current to 3 mA when load over-current occurs. The LDO was implemented in a 0.18 {mu}m CMOS technology. The measured result reveals that the LDO's power supply rejection (PSR) is about -58 dB and -54 dB at 20 Hz and 1 kHz respectively, the response time is 4 {mu}s and the quiescent current is 20 {mu}A. The designed LDO regulator can work with a supply voltage down to 2.0 V with a drop-out voltage of 200 mV at a maximum load current of 240 mA. (semiconductor integrated circuits)

Special feature article. Nuclear new age. Towards reform of laws and regulations

International Nuclear Information System (INIS)

Madarame, Haruki; Morokuzu, Muneo; Shiroyama, Hideaki; Nishiwaki, Yoshihiro; Marumo, Syunji; Suzuki, Takahiro; Hariyama, Hideo

2007-01-01

Since about half a century passes after the peaceful use of nuclear energy began in Japan, the safety laws and regulations of the nuclear energy becomes difficult to cope enough with the current situation without regulation structure changing. In March 2007, Tokyo University set up nuclear energy legislation study meeting' consisting of members from regulatory bodies, electric utilities, nuclear industries and others. The special feature introduces five opinions obtained through the argument in the meeting. As an example, Law for the Regulations of Nuclear Sources Material, Nuclear Fuel Material and Reactors is applied to basic design about the commercial reactors, but Electric Utilities Industry Law is applied to a detailed design, and different licensing standard is applied in each. Taking the adjustment of licensing standard with unifying these is necessary for efficiency. In addition, current law for the Regulations of Nuclear Sources Material, Nuclear Fuel Material and Reactors regulates according to the businesses such as reactor facilities, fuel fabrication plants and radioactive waste disposal. As for plural businesses, a low procedure and safety measures are demanded every each business. It is also necessary to include structure of the comprehensive licensing that assumed an enterprise running plural businesses. (T. Tanaka)

Audit Risk Assessment in the Light of Current European Regulations

Directory of Open Access Journals (Sweden)

Ciprian-Costel Munteanu

2015-06-01

Full Text Available Recent European reforms on audit regulations have been motivated by efforts to increase audit quality, functioning and performance. We believe the adoption of Directive 2014/56 and Regulation 537/2014 strengthened the role of independent audit and risk committees, which will positively contribute towards audit quality. This paper aims to critically assess the status quo of audit risk assessment in current European standards and regulations, by conducting a theoretical analysis of different aspects of audit risk. Our main objective is to stress the importance of detecting inherent and control risk, which lead to material misstatement at the assertion level. They need to be assessed so as to determine the nature, timing and extent of further audit procedures necessary to obtain sufficient appropriate audit evidence. These pieces of evidence enable the auditor to express an opinion on the financial statements at an acceptably low level of audit risk. Therefore, we point to the fact that researchers as well as practitioners and policymakers have to be careful when using audit tools and assessing risk levels, as their conclusions continuously shape the regulations.

Current Status and Open Issues of the 235U Evaluation. Summary Report of an IAEA Consultants’ Meeting

International Nuclear Information System (INIS)

Noguere, Gilles; Trkov, Andrej

2016-08-01

The objective of this consultancy meeting was to discuss the status of the 235 U neutron cross sections from the thermal to MeV energy ranges, to identify the main difficulties and to propose recommendations for improving the current experimental and evaluation works

Audio-Visual Processing in Meetings: Seven Questions and Current AMI Answers

NARCIS (Netherlands)

Al-Hamas, Marc; Hain, Thomas; Cernocky, Jan; Schreiber, Sascha; Poel, Mannes; Rienks, R.J.

2007-01-01

The project Augmented Multi-party Interaction (AMI) is concerned with the development of meeting browsers and remote meeting assistants for instrumented meeting rooms – and the required component technologies R&D themes: group dynamics, audio, visual, and multimodal processing, content abstraction,

Answers to questions at public meetings regarding implementation of Title 10, Code of Federal Regulations, Part 55 on operators' licenses

International Nuclear Information System (INIS)

1987-11-01

This document presents questions and answers based on the transcripts of four public meetings (and from written questions submitted after the meetings) conducted from April 9 to April 20, 1987 by the staff of the US Nuclear Regulatory Commission. The meetings discussed implementation of the Commission's final rule governing Operators' Licenses and Conforming Amendments (10 CFR Parts 55 and 50). The rule became effective May 26, 1987 and is intended to clarify the regulations for issuing licenses to operators and senior operators; revise the requirements and scope of written examinations and operating tests for operators and senior operators, require a simulation facility; clarify procedures for administering requalification examinations; and describe the form and content for operator license applications

RNAi technologies in agricultural biotechnology: The Toxicology Forum 40th Annual Summer Meeting.

Science.gov (United States)

Sherman, James H; Munyikwa, Tichafa; Chan, Stephen Y; Petrick, Jay S; Witwer, Kenneth W; Choudhuri, Supratim

2015-11-01

During the 40th Annual Meeting of The Toxicology Forum, the current and potential future science, regulations, and politics of agricultural biotechnology were presented and discussed. The meeting session described herein focused on the technology of RNA interference (RNAi) in agriculture. The general process by which RNAi works, currently registered RNAi-based plant traits, example RNAi-based traits in development, potential use of double stranded RNA (dsRNA) as topically applied pesticide active ingredients, research related to the safety of RNAi, biological barriers to ingested dsRNA, recent regulatory RNAi science reviews, and regulatory considerations related to the use of RNAi in agriculture were discussed. Participants generally agreed that the current regulatory framework is robust and appropriate for evaluating the safety of RNAi employed in agricultural biotechnology and were also supportive of the use of RNAi to develop improved crop traits. However, as with any emerging technology, the potential range of future products, potential future regulatory frameworks, and public acceptance of the technology will continue to evolve. As such, continuing dialogue was encouraged to promote education of consumers and science-based regulations. Copyright © 2015 Elsevier Inc. All rights reserved.

49 CFR 260.19 - Preapplication meeting.

Science.gov (United States)

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Preapplication meeting. 260.19 Section 260.19 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Financial Assistance § 260.19 Preapplication meeting. Potential Applicants may request a meeting with the...

Impact of new environmental and safety regulations on uranium exploration, mining, milling and management of its waste. Proceedings of a technical committee meeting

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-09-01

Concern for health, safety and the environment has grown rapidly during the last two decades. Exploitation of any mineral commodity, including uranium, involves the modification of the surrounding environment. Appropriate regulations governing such activities can assure good practices and minimize possible negative impacts on the environment and the health and safety of the workers and the general public. During the past few years, a number of countries have promulgated new regulations related to uranium exploitation, mining, milling and the related waste management. Recent regulations are stricter in terms of environmental assessment, mitigation, radiation protection and control of waste. The impact of those regulations in developed countries has resulted in better planning of operations, improvement in mine and mill designs and a more efficient approach to tailings management. The Meeting was attended by 25 participants from 17 countries representing government organizations and private industry. This document includes 21 papers presented at the Meeting on new experiences in major uranium producing countries on the subject, past producers, as well as on country where regulations and related regulatory structure are still at the early evolutionary stage. Each of the papers was indexed separately.

Impact of new environmental and safety regulations on uranium exploration, mining, milling and management of its waste. Proceedings of a technical committee meeting

International Nuclear Information System (INIS)

2001-09-01

Concern for health, safety and the environment has grown rapidly during the last two decades. Exploitation of any mineral commodity, including uranium, involves the modification of the surrounding environment. Appropriate regulations governing such activities can assure good practices and minimize possible negative impacts on the environment and the health and safety of the workers and the general public. During the past few years, a number of countries have promulgated new regulations related to uranium exploitation, mining, milling and the related waste management. Recent regulations are stricter in terms of environmental assessment, mitigation, radiation protection and control of waste. The impact of those regulations in developed countries has resulted in better planning of operations, improvement in mine and mill designs and a more efficient approach to tailings management. The Meeting was attended by 25 participants from 17 countries representing government organizations and private industry. This document includes 21 papers presented at the Meeting on new experiences in major uranium producing countries on the subject, past producers, as well as on country where regulations and related regulatory structure are still at the early evolutionary stage. Each of the papers was indexed separately

Report on the workshop "Organising, Managing and Regulating Martial Arts" during the 21st EASM conference

Directory of Open Access Journals (Sweden)

Jikkemien Vertonghen

2013-12-01

Full Text Available The present report provides a brief account of a workshop entitled “Organising, Managing and Regulating Martial Arts” organised during the 21st EASM conference held in Istanbul (Turkey on September 12th, 2013. It was the first scientific workshop with regard to the organisational and policy related aspects of (full contact martial arts. During this international meeting four scientists described in-depth the recent history and current situation regarding the organisation and regulation of martial arts in their country (i.e., France, Flanders (Belgium, Italy and the Netherlands. The workshop was a unique meeting which provided a good opportunity to obtain a better understanding of the specific situation with regard to the regulation of martial arts in some European countries and to exchange results of current research concerning this topic. Further research could be helpful to gain more insight in dealing with problems related to governance, regulation and management of martial arts within a European context.

Smart-grid investments, regulation and organization

International Nuclear Information System (INIS)

Agrell, Per J.; Bogetoft, Peter; Mikkers, Misja

2013-01-01

Grid infrastructure managers worldwide are facing demands for reinvestments in new assets with higher on-grid and off-grid functionality in order to meet new environmental targets. The roles of the current actors will change as the vertical interfaces between regulated and unregulated tasks become blurred. In this paper, we characterize some of the effects of new asset investments policy on the network tasks, assets and costs and contrast this with the assumptions of the current economic network regulation. To provide structure, we present a model of investment provision under regulation between a distribution system operator and a potential investor–generator. The results from the model confirm the hypothesis that network regulation should find a focal point, should integrate externalities in the performance assessment and should avoid wide delegation of contracting-billing for smart-grid investments. - Highlights: ► We review regulatory solutions for smart-grid and DER investments. ► What matters more than upfront incentives is organization and delegation. ► We model regulated investment under private information by a generator or a DSO. ► Highest welfare for high-powered incentives and centralized information. ► Market approaches likely to give poor outcomes for this case.

29 CFR 1612.3 - Open meeting policy.

Science.gov (United States)

2010-07-01

... 29 Labor 4 2010-07-01 2010-07-01 false Open meeting policy. 1612.3 Section 1612.3 Labor... ACT REGULATIONS § 1612.3 Open meeting policy. (a) All meetings of the Commission shall be conducted in... adequate acoustics for persons in attendance at the meeting. (d) Observers may take still photographs and...

Remarks presented (questions/answers discussed) at public regional meetings to discuss regulations (10 CFR Part 21) for reporting of defects and noncompliance, July 12--26, 1977

International Nuclear Information System (INIS)

1977-09-01

In enacting the Energy Reorganization Act of 1974, Congress included Section 206 which requires the reporting of defects and noncompliances directly to the Nuclear Regulatory Commission (NRC). This congressional action required that the NRC promulgate rules and regulations, as necessary, to assure appropriate implementation of Section 206. In response to this mandate, the NRC drafted a new regulation. Following a period of public comment and revision, the regulation identified as 10 CFR Part 21, Reporting Defects and Noncompliance, was published in a Federal Register Notice on June 6, 1977. To assist NRC licensees and other firms and organizations covered by the new Part 21 regulation, public regional meetings were conducted by staff representatives to explain the rule. At these meetings the staff presented prepared remarks and answered questions on the meaning and application of the rule. Staff remarks contained in the original publication of this document were also provided to those in attendance. At each meeting the staff received a request for the questions and answers discussed by the staff to be made available for use as guidance by the nuclear industry covered by the rule. It was announced that a consolidation of the staff position question/answer guidance would be made available to each organization or firm attending these meetings and for others where a request is made in accordance with the directions printed insidethe front cover of the document. The staff will be guided in its implementation and enforcement of Part 21 by the positions set forth in the document. The revision of NUREG-0302 includes the following three parts relating to 10 CFR Part 21: (1) remarks presented by staff representatives; (2) Federal Register Notice material; and (3) a consolidation of questions and answers from the public regional meetings

Current knowledge of microRNA-mediated regulation of drug metabolism in humans.

Science.gov (United States)

Nakano, Masataka; Nakajima, Miki

2018-05-01

Understanding the factors causing inter- and intra-individual differences in drug metabolism potencies is required for the practice of personalized or precision medicine, as well as for the promotion of efficient drug development. The expression of drug-metabolizing enzymes is controlled by transcriptional regulation by nuclear receptors and transcriptional factors, epigenetic regulation, such as DNA methylation and histone acetylation, and post-translational modification. In addition to such regulation mechanisms, recent studies revealed that microRNAs (miRNAs), endogenous ~22-nucleotide non-coding RNAs that regulate gene expression through the translational repression and degradation of mRNAs, significantly contribute to post-transcriptional regulation of drug-metabolizing enzymes. Areas covered: This review summarizes the current knowledge regarding miRNAs-dependent regulation of drug-metabolizing enzymes and transcriptional factors and its physiological and clinical significance. We also describe recent advances in miRNA-dependent regulation research, showing that the presence of pseudogenes, single-nucleotide polymorphisms, and RNA editing affects miRNA targeting. Expert opinion: It is unwavering fact that miRNAs are critical factors causing inter- and intra-individual differences in the expression of drug-metabolizing enzymes. Consideration of miRNA-dependent regulation would be a helpful tool for optimizing personalized and precision medicine.

LED Current Balance Using a Variable Voltage Regulator with Low Dropout vDS Control

Directory of Open Access Journals (Sweden)

Hung-I Hsieh

2017-02-01

Full Text Available A cost-effective light-emitting diode (LED current balance strategy using a variable voltage regulator (VVR with low dropout vDS control is proposed. This can regulate the multiple metal-oxide-semiconductor field-effect transistors (MOSFETs of the linear current regulators (LCR, maintaining low dropout vDS on the flat vGS-characteristic curves and making all drain currents almost the same. Simple group LCRs respectively loaded with a string LED are employed to implement the theme. The voltage VVdc from a VVR is synthesized by a string LED voltage NvD, source voltage vR, and a specified low dropout vDS = VQ. The VVdc updates instantly, through the control loop of the master LCR, which means that all slave MOSFETs have almost the same biases on their flat vGS-characteristic curves. This leads to all of the string LED currents being equal to each other, producing an almost even luminance. An experimental setup with microchip control is built to verify the estimations. Experimental results show that the luminance of all of the string LEDs are almost equal to one another, with a maximum deviation below 1% during a wide dimming range, while keeping all vDS of the MOSFETs at a low dropout voltage, as expected.

12 CFR 407.2 - Closing meetings.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Closing meetings. 407.2 Section 407.2 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES REGULATIONS GOVERNING PUBLIC OBSERVATION OF EX-IM BANK MEETINGS § 407.2 Closing meetings. (a) Except where Eximbank finds that the public interest requires...

Identifying, meeting, and assessing customer expectations

International Nuclear Information System (INIS)

Danner, T.A.

1995-01-01

Maintaining proficiency in carrying out mission goals is fundamental to the success of any organization. The definitive mission of the Waste Management and Remedial Action Division (WMRAD) of Oak Ridge National Laboratory (ORNL) is open-quotes to conduct waste management activities in a compliant, publicly acceptable, technically sound, and cost-efficient mannerclose quotes. In order to effectively fulfill this mission, must meet or exceed several standards in respect to our customers. These include: (1) identifying current and future customer expectations; (2) managing our relationships with our customers; (3) ensuring our commitment to our customers; and (4) measuring our success m customer satisfaction. Our customers have a great variety of requirements and expectations. Many of these are in the form of local, state, and federal regulations and environmental standards. Others are brought to our attention through inquires made to the Department of Energy (DOE).Consumer surveys have proven to be effective tools which have been used to make improvements, enhance certain program elements, and identify beneficial areas in already existing programs. In addition, national working groups, technology transfer meetings, and manager/contractor's meeting offer excellent opportunities to assess our activities

Regulated software meets DevOps

DEFF Research Database (Denmark)

Laukkarinen, Teemu; Kuusinen, Kati; Mikkonen, Tommi

2018-01-01

Context: Regulatory authorities require proofs from critical systems manufacturers that the software in their products is developed in accordance to prescribed development practices before accepting the product to the markets. This is challenging when using DevOps, where continuous integration...... and deployment are the default practices, which are not a good match with the regulatory software development standards. Objective: We aim to bring DevOps and regulated software development closer to each other. First, we want to make it easier for developers to develop regulated software with tools...... and practices they are familiar with. Second, we want to allow regulatory authorities to build confidence on solutions provided by manufacturers by defining a mapping between DevOps and regulatory software development. Method: We performed a literature survey and created research suggestions using exploratory...

SU-A-210-00: AAPM Medical Physics Student Meeting: Medical Billing and Regulations: Everything You Always Wanted To Know, But Were Too Afraid To Ask

Energy Technology Data Exchange (ETDEWEB)

NONE

2015-06-15

The purpose of this student annual meeting is to address topics that are becoming more relevant to medical physicists, but are not frequently addressed, especially for students and trainees just entering the field. The talk is divided into two parts: medical billing and regulations. Hsinshun Wu – Why should we learn radiation oncology billing? Many medical physicists do not like to be involved with medical billing or coding during their career. They believe billing is not their responsibility and sometimes they even refuse to participate in the billing process if given the chance. This presentation will talk about a physicist’s long career and share his own experience that knowing medical billing is not only important and necessary for every young medical physicist, but that good billing knowledge could provide a valuable contribution to his/her medical physics development. Learning Objectives: The audience will learn the basic definition of Current Procedural Terminology (CPT) codes performed in a Radiation Oncology Department. Understand the differences between hospital coding and physician-based or freestanding coding. Apply proper CPT coding for each Radiation Oncology procedure. Each procedure with its specific CPT code will be discussed in detail. The talk will focus on the process of care and use of actual workflow to understand each CPT code. Example coding of a typical Radiation Oncology procedure. Special procedure coding such as brachytherapy, proton therapy, radiosurgery, and SBRT. Maryann Abogunde – Medical physics opportunities at the Nuclear Regulatory Commission (NRC) The NRC’s responsibilities include the regulation of medical uses of byproduct (radioactive) materials and oversight of medical use end-users (licensees) through a combination of regulatory requirements, licensing, safety oversight including inspection and enforcement, operational experience evaluation, and regulatory support activities. This presentation will explore the

SU-A-210-00: AAPM Medical Physics Student Meeting: Medical Billing and Regulations: Everything You Always Wanted To Know, But Were Too Afraid To Ask

International Nuclear Information System (INIS)

2015-01-01

The purpose of this student annual meeting is to address topics that are becoming more relevant to medical physicists, but are not frequently addressed, especially for students and trainees just entering the field. The talk is divided into two parts: medical billing and regulations. Hsinshun Wu – Why should we learn radiation oncology billing? Many medical physicists do not like to be involved with medical billing or coding during their career. They believe billing is not their responsibility and sometimes they even refuse to participate in the billing process if given the chance. This presentation will talk about a physicist’s long career and share his own experience that knowing medical billing is not only important and necessary for every young medical physicist, but that good billing knowledge could provide a valuable contribution to his/her medical physics development. Learning Objectives: The audience will learn the basic definition of Current Procedural Terminology (CPT) codes performed in a Radiation Oncology Department. Understand the differences between hospital coding and physician-based or freestanding coding. Apply proper CPT coding for each Radiation Oncology procedure. Each procedure with its specific CPT code will be discussed in detail. The talk will focus on the process of care and use of actual workflow to understand each CPT code. Example coding of a typical Radiation Oncology procedure. Special procedure coding such as brachytherapy, proton therapy, radiosurgery, and SBRT. Maryann Abogunde – Medical physics opportunities at the Nuclear Regulatory Commission (NRC) The NRC’s responsibilities include the regulation of medical uses of byproduct (radioactive) materials and oversight of medical use end-users (licensees) through a combination of regulatory requirements, licensing, safety oversight including inspection and enforcement, operational experience evaluation, and regulatory support activities. This presentation will explore the

76 FR 77558 - Sunshine Act Meeting; Notice

Science.gov (United States)

2011-12-13

... LEGAL SERVICES CORPORATION Sunshine Act Meeting; Notice DATES: Date and Time: The Legal Services Corporation's Operations & Regulations Committee will meet December 16, 2011. The meeting will commence at 4 p... Bylaws necessitated by the DC Nonprofit Corporation Act of 2010. 3. Public comment. 4. Consider and act...

Radiofrequency launchers for plasma heating and current drive. Report on the IAEA Technical Committee Meeting, held at Naka-machi, Ibaraki-ken, Japan, 10-12 November 1993

International Nuclear Information System (INIS)

Kimura, H.; Imai, T.; Yamamoto, T.

1995-01-01

The objective of the meeting was to review the present status of the plasma and RF launcher interaction for plasma heating and current drive in various frequency regimes (ion cyclotron to electron cyclotron) and to discuss a possible technical solution for the RF launchers to be installed on large fusion machines. The 23 papers presented during the meeting can be found in the published proceedings. This report of the meeting includes the various contributions presented at the meeting in summary fashion, describing the status of the heating and current drive experiments and the technologies of launching systems with different frequencies, innovative ideas for launching systems for next stage large fusion devices and new RF systems under development. 23 refs, 3 tabs

A current-mode voltage regulator with an embedded sub-threshold reference for a passive UHF RFID transponder

Energy Technology Data Exchange (ETDEWEB)

Liu Zhongqi [Department of Electronic Engineering, Tsinghua University, Beijing 100084 (China); Zhang Chun; Li Yongming; Wang Zhihua, E-mail: liu-zq04@mails.tsinghua.edu.c [Institute of Microelectronics, Tsinghua University, Beijing 100084 (China)

2010-06-15

This paper presents a current-mode voltage regulator for a passive UHF RFID transponder. The passive tag power is extracted from RF energy through the RF-to-DC rectifier. Due to huge variations of the incoming RF power, the rectifier output voltage should be regulated to achieve a stable power supply. By accurately controlling the current flowing into the load with an embedded sub-threshold reference, the regulated voltage varies in a range of 1-1.3 V from -20 to 80 {sup 0}C, and a bandwidth of about 100 kHz is achieved for a fast power recovery. The circuit is fabricated in UMC 0.18 {mu}m mixed-mode CMOS technology, and the current consumption is only 1 {mu}A. (semiconductor integrated circuits)

A current-mode voltage regulator with an embedded sub-threshold reference for a passive UHF RFID transponder

International Nuclear Information System (INIS)

Liu Zhongqi; Zhang Chun; Li Yongming; Wang Zhihua

2010-01-01

This paper presents a current-mode voltage regulator for a passive UHF RFID transponder. The passive tag power is extracted from RF energy through the RF-to-DC rectifier. Due to huge variations of the incoming RF power, the rectifier output voltage should be regulated to achieve a stable power supply. By accurately controlling the current flowing into the load with an embedded sub-threshold reference, the regulated voltage varies in a range of 1-1.3 V from -20 to 80 0 C, and a bandwidth of about 100 kHz is achieved for a fast power recovery. The circuit is fabricated in UMC 0.18 μm mixed-mode CMOS technology, and the current consumption is only 1 μA. (semiconductor integrated circuits)

Circumpolar Biodiversity Monitoring Programme: Coastal Expert Workshop meeting summary

Science.gov (United States)

Thomson, L.; McLennan, Donald; Anderson, Rebecca D.; Wegeberg, S.; Pettersvik Arvnes, Maria; Sergienko, Liudmila; Behe, Carolina; Moss-Davies, Pitseolak; Fritz, S.; Christensen, T.; Price, C.

2016-01-01

The Coastal Expert Workshop brought together a diverse group of coastal experts with the common goal of developing a biodiversity monitoring program for coastal ecosystems across the circumpolar Arctic. Meeting participants, including northern residents, industry and Non-Governmental Organization (NGO) representatives, scientists, and government regulators from across the circumpolar Arctic, gathered at the Lord Elgin Hotel in Ottawa from March 1 to 3, 2016, to discuss current biodiversity monitoring efforts, understand key issues facing biodiversity in the Arctic coastal areas and suggest monitoring indicators, or Focal Ecosystem Components, for the program. A Traditional Knowledge Holders meeting was held on February 29, 2016 in conjunction with the workshop. The following document provides a summary of the workshop activities and outcomes, and will be followed by a more complete Workshop Report.

75 FR 8682 - Sunshine Act Meetings

Science.gov (United States)

2010-02-25

... futures and options in the precious and base metals markets, and to consider Federal position limits in... precious and base metals markets and related hedge exemptions on regulated futures exchanges, derivatives... COMMODITY FUTURES TRADING COMMISSION Sunshine Act Meetings Agency Holding the Meeting: Commodity...

76 FR 20050 - Sunshine Act Meetings

Science.gov (United States)

2011-04-11

... LEGAL SERVICES CORPORATION Sunshine Act Meetings Notice DATE AND TIME: The Legal Services... run concurrently after the meeting of the Finance Committee. LOCATION: The Westin Hotel, 6631 Broad.... Promotion & Provision for the Delivery 9 a.m. of Legal Services Committee. 2. Operations & Regulations...

Current regulator for stabilizing electrostatic generators; Regulateur de courant pour stabilisation de generateur electrostatique

Energy Technology Data Exchange (ETDEWEB)

Gabet, A; Taieb, J

1950-07-01

An instrument consisting of two electronic tubes, a triode and a pentode, connected in series, serves as a stabilizer of the current that charges a working model of a van de Graaff generator. The current is maintained at a level corresponding to an auxiliary variable voltage. The triode maintains that voltage, while the pentode regulates the current. Another application of the circuit, viz., the stabilizing of the generator voltage, will be described elsewhere. (author)

Future carbon regulations and current investments in alternative coal-fired power plant technologies

International Nuclear Information System (INIS)

Sekar, Ram C.; Parsons, John E.; Herzog, Howard J.; Jacoby, Henry D.

2007-01-01

We analyze how uncertain future US carbon regulations shape the current choice of the type of power plant to build. Our focus is on two coal-fired technologies, pulverized coal (PC) and integrated coal gasification combined cycle technology (IGCC). The PC technology is cheapest-assuming there is no need to control carbon emissions. The IGCC technology may be cheaper if carbon must be captured. Since power plants last many years and future regulations are uncertain, a US electric utility faces a standard decision under uncertainty. A company will confront the range of possible outcomes, assigning its best estimate of the probability of each scenario, averaging the results and determining the power plant technology with the lowest possible cost inclusive of expected future carbon related costs, whether those costs be in the form of emissions charges paid or capital expenditures for retrofitting to capture carbon. If the company assigns high probability to no regulation or to less stringent regulation of carbon, then it makes sense for it to build the PC plant. But if it assigns sufficient probability to scenarios with more stringent regulation, then the IGCC technology is warranted. We provide some useful benchmarks for possible future regulation and show how these relate back to the relative costs of the two technologies and the optimal technology choice. Few of the policy proposals widely referenced in the public discussion warrant the choice of the IGCC technology. Instead, the PC technology remains the least costly. However, recent carbon prices in the European Emissions Trading System are higher than these benchmarks. If it is any guide to possible future penalties for emissions in the US, then current investment in the IGCC technology is warranted. Of course, other factors need to be factored into the decision as well

Process stabilization by peak current regulation in reactive high-power impulse magnetron sputtering of hafnium nitride

International Nuclear Information System (INIS)

Shimizu, T; Villamayor, M; Helmersson, U; Lundin, D

2016-01-01

A simple and cost effective approach to stabilize the sputtering process in the transition zone during reactive high-power impulse magnetron sputtering (HiPIMS) is proposed. The method is based on real-time monitoring and control of the discharge current waveforms. To stabilize the process conditions at a given set point, a feedback control system was implemented that automatically regulates the pulse frequency, and thereby the average sputtering power, to maintain a constant maximum discharge current. In the present study, the variation of the pulse current waveforms over a wide range of reactive gas flows and pulse frequencies during a reactive HiPIMS process of Hf-N in an Ar–N 2 atmosphere illustrates that the discharge current waveform is a an excellent indicator of the process conditions. Activating the reactive HiPIMS peak current regulation, stable process conditions were maintained when varying the N 2 flow from 2.1 to 3.5 sccm by an automatic adjustment of the pulse frequency from 600 Hz to 1150 Hz and consequently an increase of the average power from 110 to 270 W. Hf–N films deposited using peak current regulation exhibited a stable stoichiometry, a nearly constant power-normalized deposition rate, and a polycrystalline cubic phase Hf-N with (1 1 1)-preferred orientation over the entire reactive gas flow range investigated. The physical reasons for the change in the current pulse waveform for different process conditions are discussed in some detail. (paper)

Logic Meeting

CERN Document Server

Tugué, Tosiyuki; Slaman, Theodore

1989-01-01

These proceedings include the papers presented at the logic meeting held at the Research Institute for Mathematical Sciences, Kyoto University, in the summer of 1987. The meeting mainly covered the current research in various areas of mathematical logic and its applications in Japan. Several lectures were also presented by logicians from other countries, who visited Japan in the summer of 1987.

Development of Thresholds and Exceedance Probabilities for Influent Water Quality to Meet Drinking Water Regulations

Science.gov (United States)

Reeves, K. L.; Samson, C.; Summers, R. S.; Balaji, R.

2017-12-01

Drinking water treatment utilities (DWTU) are tasked with the challenge of meeting disinfection and disinfection byproduct (DBP) regulations to provide safe, reliable drinking water under changing climate and land surface characteristics. DBPs form in drinking water when disinfectants, commonly chlorine, react with organic matter as measured by total organic carbon (TOC), and physical removal of pathogen microorganisms are achieved by filtration and monitored by turbidity removal. Turbidity and TOC in influent waters to DWTUs are expected to increase due to variable climate and more frequent fires and droughts. Traditional methods for forecasting turbidity and TOC require catchment specific data (i.e. streamflow) and have difficulties predicting them under non-stationary climate. A modelling framework was developed to assist DWTUs with assessing their risk for future compliance with disinfection and DBP regulations under changing climate. A local polynomial method was developed to predict surface water TOC using climate data collected from NOAA, Normalized Difference Vegetation Index (NDVI) data from the IRI Data Library, and historical TOC data from three DWTUs in diverse geographic locations. Characteristics from the DWTUs were used in the EPA Water Treatment Plant model to determine thresholds for influent TOC that resulted in DBP concentrations within compliance. Lastly, extreme value theory was used to predict probabilities of threshold exceedances under the current climate. Results from the utilities were used to produce a generalized TOC threshold approach that only requires water temperature and bromide concentration. The threshold exceedance model will be used to estimate probabilities of exceedances under projected climate scenarios. Initial results show that TOC can be forecasted using widely available data via statistical methods, where temperature, precipitation, Palmer Drought Severity Index, and NDVI with various lags were shown to be important

Providing current radiation safety according to new version of 'Ukrytie' object regulation

International Nuclear Information System (INIS)

Borovoj, A.A.; Vysotskij, E.D.; Krinitsyn, A.P.; Bogatov, S.A.

1999-01-01

Main provisions are given of the 'Ukryttia' object's Regulation related to provision of radiation safety during the object's operation. The safety is provided due to the realization by the object's personnel of functions of global monitoring of current radiation conditions, as well as of the measures of operative or preventive suppression of radiation abnormalities sources

Technical Meeting on Impact of Fukushima Event on Current and Future Fast Reactor Designs. Presentations

International Nuclear Information System (INIS)

2012-01-01

The overall purpose of the Technical Meeting was to recognize and analyse the implications of the accident occurred at the Fukushima Dai-ichi Nuclear Power Station on current and future fast neutron systems design and operation. The aim was to provide a global forum for discussing the principal lessons learned from this event, and thus to review safety principles and characteristics of existing and future fast neutron concepts, especially in relation with extreme natural events which potentially may lead to severe accident scenarios. The participants also presented and discussed innovative technical solutions, design features and countermeasures for design extension conditions - including earthquakes, tsunami and other extreme natural hazards - which can enhance the safety level of existing and future fast neutron systems. Furthermore, the meeting gave the opportunity to present advanced methods for the evaluation of the robustness of plants against design extension conditions. Another important goal of this TM was to discuss how to harmonize safety approaches and goals for next generation’s fast reactors. Finally, the meeting was intended to identify areas where further research and development in nuclear safety, technology and engineering in the light of the Fukushima accident are needed. In the frame of the implementation of its Nuclear Safety Action Plan endorsed by all Member States, the IAEA will consider these areas as potential technical topics for new Coordinated Research Projects, to be launched in the near future

LARP6 Meets Collagen mRNA: Specific Regulation of Type I Collagen Expression

Directory of Open Access Journals (Sweden)

Yujie Zhang

2016-03-01

Full Text Available Type I collagen is the most abundant structural protein in all vertebrates, but its constitutive rate of synthesis is low due to long half-life of the protein (60–70 days. However, several hundred fold increased production of type I collagen is often seen in reparative or reactive fibrosis. The mechanism which is responsible for this dramatic upregulation is complex, including multiple levels of regulation. However, posttranscriptional regulation evidently plays a predominant role. Posttranscriptional regulation comprises processing, transport, stabilization and translation of mRNAs and is executed by RNA binding proteins. There are about 800 RNA binding proteins, but only one, La ribonucleoprotein domain family member 6 (LARP6, is specifically involved in type I collagen regulation. In the 5′untranslated region (5’UTR of mRNAs encoding for type I and type III collagens there is an evolutionally conserved stem-loop (SL structure; this structure is not found in any other mRNA, including any other collagen mRNA. LARP6 binds to the 5′SL in sequence specific manner to regulate stability of collagen mRNAs and their translatability. Here, we will review current understanding of how is LARP6 involved in posttranscriptional regulation of collagen mRNAs. We will also discuss how other proteins recruited by LARP6, including nonmuscle myosin, vimentin, serine threonine kinase receptor associated protein (STRAP, 25 kD FK506 binding protein (FKBP25 and RNA helicase A (RHA, contribute to this process.

Current environmental regulations

International Nuclear Information System (INIS)

Martz, M.K.

1985-01-01

An overview of the Federal environmental statutes and implementation regulations is provided, including the National Environmental Policy Act, the Clean Air Act, the Clean Water Act, the Safe Drinking Water Act, the Resource Conservation and Recovery Act, the Comprehensive Environmental Response, Compensation, and Liability Act, the Toxic Substances Control Act, the Federal Insecticide, Fungicide, and Rodenticide Act, and the Endangered Species Act. Recent developments which may have a direct impact on waste repository siting and management activities include: final promulgation of National Emission Standards for hazardous Air Pollutants for radionuclides, the DOE-EPA memorandum of understanding which brings mixed radioactive and chemical waste under the requirements of RCRA, and the proposed designation of additional sole source aquifers

Periodic Safety Review in Interim Storage Facilities - Current Regulation and Experiences in Germany

International Nuclear Information System (INIS)

Neles, Julia Mareike; Schmidt, Gerhard

2014-01-01

Periodic safety reviews in nuclear power plants in Germany have been performed since the end of the 1980's as an indirect follow-up of the accident in Chernobyl and, in the meantime, are formally required by law. During this process the guidelines governing this review were developed in stages and reached their final form in 1996. Interim storage facilities and other nuclear facilities at that time were not included, so the guidelines were solely focused on the specific safety issues of nuclear power plants. Following IAEA's recommendations, the Western European Nuclear Regulator Association (WENRA) introduced PSRs in its safety reference levels for storage facilities (current version in WGWD report 2.1 as of Feb 2011: SRLs 59 - 61). Based on these formulations, Germany improved its regulation in 2010 with a recommendation of the Nuclear Waste Management Commission (Entsorgungskommission, ESK), an expert advisory commission for the federal regulatory body BMU. The ESK formulated these detailed requirements in the 'ESK recommendation for guides to the performance of periodic safety reviews for interim storage facilities for irradiated fuel elements and heat-generating radioactive waste'. Before finalization of the guideline a test phase was introduced, aimed to test the new regulation in practice and to later include the lessons learned in the final formulation of the guideline. The two-year test phase started in October 2011 in which the performance of a PSR will be tested at two selected interim storage facilities. Currently these recommendations are discussed with interested/concerned institutions. The results of the test phase shall be considered for improvements of the draft and during the final preparation of guidelines. Currently the PSR for the first ISF is in an advanced stage, the second facility just started the process. Preliminary conclusions from the test phase show that the implementation of the draft guideline requires interpretation. The aim of a

Current Rates of Publication for Podium and Poster Presentations at the American Society for Surgery of the Hand Annual Meetings

Directory of Open Access Journals (Sweden)

Joshua M. Abzug

2014-09-01

 Currently, fewer than half of the studies presented at Annual Meetings of the ASSH achieve publication in peer-eviewed journals. Presentations are most likely to be published within 3 years, and almost half are published in Journal of Hand Surgery . 

Meeting report: Ocean 'omics science, technology and cyberinfrastructure: current challenges and future requirements (August 20-23, 2013).

Science.gov (United States)

Gilbert, Jack A; Dick, Gregory J; Jenkins, Bethany; Heidelberg, John; Allen, Eric; Mackey, Katherine R M; DeLong, Edward F

2014-06-15

The National Science Foundation's EarthCube End User Workshop was held at USC Wrigley Marine Science Center on Catalina Island, California in August 2013. The workshop was designed to explore and characterize the needs and tools available to the community that is focusing on microbial and physical oceanography research with a particular emphasis on 'omic research. The assembled researchers outlined the existing concerns regarding the vast data resources that are being generated, and how we will deal with these resources as their volume and diversity increases. Particular attention was focused on the tools for handling and analyzing the existing data, on the need for the construction and curation of diverse federated databases, as well as development of shared, interoperable, "big-data capable" analytical tools. The key outputs from this workshop include (i) critical scientific challenges and cyber infrastructure constraints, (ii) the current and future ocean 'omics science grand challenges and questions, and (iii) data management, analytical and associated and cyber-infrastructure capabilities required to meet critical current and future scientific challenges. The main thrust of the meeting and the outcome of this report is a definition of the 'omics tools, technologies and infrastructures that facilitate continued advance in ocean science biology, marine biogeochemistry, and biological oceanography.

Scientific meetings

International Nuclear Information System (INIS)

1973-01-01

One of the main aims of the IAEA is to foster the exchange of scientific and technical information and one of the main ways of doing this is to convene international scientific meetings. They range from large international conferences bringing together several hundred scientists, smaller symposia attended by an average of 150 to 250 participants and seminars designed to instruct rather than inform, to smaller panels and study groups of 10 to 30 experts brought together to advise on a particular programme or to develop a set of regulations. The topics of these meetings cover every part of the Agency's activities and form a backbone of many of its programmes. (author)

Voltage and Current Regulators Design of Power Converters in Islanded Microgrids based on State Feedback Decoupling

DEFF Research Database (Denmark)

Federico, de Bosio; de Sousa Ribeiro, Luiz Antonio; Freijedo Fernandez, Francisco Daniel

2016-01-01

In stand-alone microgrids based on voltage source inverters state feedback coupling between the capacitor voltage and inductor current degrades significantly the dynamics performance of voltage and current regulators. The decoupling of the controlled states is proposed, considering the limitations...

SOME CONSIDERATIONS OVER THE INTERNAL CONTROL IN THE CONTEXT OF CURRENT ACCOUNTANCY REGULATIONS

Directory of Open Access Journals (Sweden)

Lenghel Dorin Radu

2012-12-01

Full Text Available Through the hereby study we set ourselves on an analysis over the internal control and the ways of implementation of it. The final purpose of our research is represented by the characteristics of the internal control system in the context of current accountancy regulations. The accomplishment of such goal has forced us to research the current literature in the area and also the legal regulations over internal control. Of course, the accomplishment of such a research was possible only after a pertinent analysis over the opinions expressed in specialty literature regarding this area. Our research wants to be with a theoretical and applicative character. It is based on analysing the internal control system, the methodology of internal control and the steps of internal control. We express our belief that the implementation of the internal control in a very exact manner comes as an aid to the company management and lead to the accomplishment of managerial objectives and policies. In what it regards the result of our research there can be drawn the following conclusions: from the legal regulations (OMFP nr. 3055/2009, there is no clear conclusion over the procedures and policies of implementation of internal control applicable to an economical entity; also there are not presented in a detailed way the types (forms of internal control, being presented in the legal regulations only a classification of them after the time in which they are exercised (before, during or after the finishing of the operations; also in the legal regulations there is developed a certain way of internal control, represented by the financial and accounting internal control, as if the other forms of internal control do not exist; in what regards the components of internal control, these are presented in another way, but similar to already known models of internal control (Coso and Coco; also in the legal regulations there are presented the general objectives of internal control

Early response to sibutramine in patients not meeting current label criteria: preliminary analysis of SCOUT lead-in period

DEFF Research Database (Denmark)

Caterson, Ian; Coutinho, Walmir; Finer, Nick

2010-01-01

The Sibutramine Cardiovascular Outcomes (SCOUT) trial protocol defines a patient population predominantly outside current European Union label criteria. This article explores responses to sibutramine during the 6-week, single-blind, lead-in period between patients who conformed to the label...... requirements ("conformers") and those who did not ("nonconformers"). SCOUT is an ongoing, randomized, double-blind, placebo-controlled outcome trial in overweight/obese patients at high risk of a cardiovascular event. In total, 10,742 patients received sibutramine and weight management during the lead...... with sibutramine confirms its good tolerability and efficacy in patients who meet current label criteria. Preliminary data from high-risk patients for whom sibutramine is currently contraindicated suggest a low discontinuation rate and few serious adverse events but confirmation from the SCOUT outcome data...

75 FR 28806 - Sunshine Act Meeting

Science.gov (United States)

2010-05-24

... meeting are: Open Session A. Approval of Minutes May 13, 2010. B. New Business--Regulations Advance Notice... June 10, 2010, from 9 a.m. until such time as the Board concludes its business. FOR FURTHER INFORMATION.... SUPPLEMENTARY INFORMATION: Parts of this meeting of the Board will be open to the public (limited space...

4th IEA International CCS Regulatory Network Meeting

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-07-01

On 9 and 10 May 2012, the IEA International CCS Regulatory Network (Network), launched in Paris in May 2008 to provide a neutral forum for CCS regulators, policy makers and stakeholders to share updates and views on CCS regulatory developments, held its fourth meeting at the International Energy Agency (IEA) offices in Paris, France. The aim of the meeting was to: provide an update on government efforts to develop and implement carbon capture and storage (CCS) legal and regulatory frameworks; and consider ways in which governments are dealing with some of the more difficult or complex aspects of CCS regulation. This report summarises the proceedings of the meeting.

1990 Fall Meeting Report

Science.gov (United States)

Chapman, David S.

The AGU 1990 Fall Meeting, held in San Francisco December 3-7, continued the steady growth trend for the western meeting set over the last decade. About 5200 members registered for the meeting and 3836 papers were given. The scientific kickoff to the meeting was provided by a Union session on initial results of the current Magellan mission to Venus. The mission was also the focus of a public lecture and short film on highlights of the mission and an extensive Union poster session.

Public meetings

CERN Multimedia

Staff Association

2017-01-01

Do you have questions about the elections to the Staff Council, 2017 MERIT exercise, EVE and School, LD to IC exercise, CHIS, the Pension Fund… Come get informed and ask your questions at our public meetings. These public meetings are also an opportunity to get the more information on current issues. Benefit from this occasion to get the latest news and to discuss with the representatives of the statutory body that is the Staff Association!

8. Danish meeting for marine researchers

International Nuclear Information System (INIS)

1994-01-01

The publication comprises the programme for the 8th Danish meeting for marine researchers held in Odense (Denmark) on January 25th - 27th, 1994, and the abstracts of the papers that were presented at that meeting. Subjects covered are marine biology, sediments and sedimentation, fish, fishing and fishing regulation, marine processes and the monitoring of Danish straits. (AB)

The 10. Danish marine research meeting

International Nuclear Information System (INIS)

1998-01-01

The publication comprises the programme for the 10th Danish meeting for marine researchers held in Hirtshals (Denmark) on January 21 - 27, 1998, and the abstracts of the papers that were presented at that meeting. Subjects covered are marine biology, sediments and sedimentation, fish, fishing and fishing regulations, marine processes and the monitoring of Danish straits. (EG)

Smart-Grid Investments, Regulation and Organization

DEFF Research Database (Denmark)

Agrell, Per J.; Bogetoft, Peter

on the network tasks, assets and costs and contrast this with the assumptions implicit or explicit in current economic network regulation. The resulting challenge is identified as the change in the direction of higher asymmetry of information and higher capital intensity, combined with ambiguities in terms......Worldwide, but in particular in North America and Europe, the grid infrastructure managers are facing demands for reinvestments in new assets with higher on-grid and off-grid functionality in order to promote energy efficiency and low-carbon conversion of the energy sector. To meet societal policy...

Exploring Faraday's Law of Electrolysis Using Zinc-Air Batteries with Current Regulative Diodes

Science.gov (United States)

Kamata, Masahiro; Paku, Miei

2007-01-01

Current regulative diodes (CRDs) are applied to develop new educational experiments on Faraday's law by using a zinc-air battery (PR2330) and a resistor to discharge it. The results concluded that the combination of zinc-air batteries and the CRD array is simpler, less expensive, and quantitative and gives accurate data.

Regulation of zebrafish sleep and arousal states: current and prospective approaches

Directory of Open Access Journals (Sweden)

Cindy N Chiu

2013-04-01

Full Text Available Every day, we shift among various states of sleep and arousal to meet the many demands of our bodies and environment. A central puzzle in neurobiology is how the brain controls these behavioral states, which are essential to an animal’s well-being and survival. Mammalian models have predominated sleep and arousal research, although in the past decade, invertebrate models have made significant contributions to our understanding of the genetic underpinnings of behavioral states. More recently, the zebrafish has emerged as a promising model system for sleep and arousal research. Here we review experimental evidence that the zebrafish, a diurnal vertebrate, exhibits fundamental behavioral and neurochemical characteristics of mammalian sleep and arousal. We also propose how specific advantages of the zebrafish can be harnessed to advance the field. These include tractable genetics to identify and manipulate molecular and cellular regulators of behavioral states, optical transparency to facilitate in vivo observation of neural structure and function, and amenability to high-throughput drug screens to discover novel therapies for neurological disorders.

Technical Meeting on Impact of Fukushima Event on Current and Future Fast Reactor Designs. Working Material

International Nuclear Information System (INIS)

2012-01-01

The overall purpose of the Technical Meeting was to recognize and analyse the implications of the accident occurred at the Fukushima Dai-ichi Nuclear Power Station on current and future fast neutron systems design and operation. The aim was to provide a global forum for discussing the principal lessons learned from this event, and thus to review safety principles and characteristics of existing and future fast neutron concepts, especially in relation with extreme natural events which potentially may lead to severe accident scenarios. The participants also presented and discussed innovative technical solutions, design features and countermeasures for design extension conditions - including earthquakes, tsunami and other extreme natural hazards - which can enhance the safety level of existing and future fast neutron systems. Furthermore, the meeting gave the opportunity to present advanced methods for the evaluation of the robustness of plants against design extension conditions. Another important goal of this TM was to discuss how to harmonize safety approaches and goals for next generation’s fast reactors. Finally, the meeting was intended to identify areas where further research and development in nuclear safety, technology and engineering in the light of the Fukushima accident are needed. In the frame of the implementation of its Nuclear Safety Action Plan endorsed by all Member States, the IAEA will consider these areas as potential technical topics for new Coordinated Research Projects, to be launched in the near future

Meeting report: Ocean ‘omics science, technology and cyberinfrastructure: current challenges and future requirements (August 20-23, 2013)

Science.gov (United States)

Gilbert, Jack A; Dick, Gregory J.; Jenkins, Bethany; Heidelberg, John; Allen, Eric; Mackey, Katherine R. M.

2014-01-01

The National Science Foundation’s EarthCube End User Workshop was held at USC Wrigley Marine Science Center on Catalina Island, California in August 2013. The workshop was designed to explore and characterize the needs and tools available to the community that is focusing on microbial and physical oceanography research with a particular emphasis on ‘omic research. The assembled researchers outlined the existing concerns regarding the vast data resources that are being generated, and how we will deal with these resources as their volume and diversity increases. Particular attention was focused on the tools for handling and analyzing the existing data, on the need for the construction and curation of diverse federated databases, as well as development of shared, interoperable, “big-data capable” analytical tools. The key outputs from this workshop include (i) critical scientific challenges and cyber infrastructure constraints, (ii) the current and future ocean ‘omics science grand challenges and questions, and (iii) data management, analytical and associated and cyber-infrastructure capabilities required to meet critical current and future scientific challenges. The main thrust of the meeting and the outcome of this report is a definition of the ‘omics tools, technologies and infrastructures that facilitate continued advance in ocean science biology, marine biogeochemistry, and biological oceanography. PMID:25197495

25 CFR 1000.225 - Are meetings or discussions mandatory?

Science.gov (United States)

2010-04-01

... FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.225 Are meetings or discussions mandatory? No, a meeting with the...

Flexible Power Regulation and Current-limited Control of Grid-connected Inverter under Unbalanced Grid Voltage Faults

DEFF Research Database (Denmark)

Guo, Xiaoqiang; Liu, Wenzhao; Lu, Zhigang

2017-01-01

The grid-connected inverters may experience excessive current stress in case of unbalanced grid voltage Fault Ride Through (FRT), which significantly affects the reliability of the power supply system. In order to solve the problem, the inherent mechanisms of the excessive current phenomenon...... with the conventional FRT solutions are discussed. The quantitative analysis of three phase current peak values are conducted and a novel current-limited control strategy is proposed to achieve the flexible active and reactive power regulation and successful FRT in a safe current operation area with the aim...

76 FR 4378 - Sunshine Act Meetings; Notice

Science.gov (United States)

2011-01-25

... concurrent meetings will be followed by the Finance Committee meeting. LOCATION: The Legal Services... & Regulations Committee.... 3. Audit Committee 11 a.m. 4. Development Committee 11 a.m. 5. Finance Committee 6... the Board of Directors so the Committee may be briefed on a matter related to the classification of...

12 CFR 407.4 - Procedures applicable to other meetings.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Procedures applicable to other meetings. 407.4 Section 407.4 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES REGULATIONS GOVERNING PUBLIC OBSERVATION OF EX-IM BANK MEETINGS § 407.4 Procedures applicable to other meetings. (a) Amendments. (1) For...

Factors affecting the regulation of pacing: current perspectives

Directory of Open Access Journals (Sweden)

Mauger AR

2014-09-01

Full Text Available Alexis R Mauger Endurance Research Group, School of Sport and Exercise Sciences, Faculty of Science, University of Kent, Chatham, UK Abstract: During prolonged dynamic and rhythmic exercise, muscular pain and discomfort arises as a result of an increased concentration of deleterious metabolites. Sensed by peripheral nociceptors and transmitted via afferent feedback to the brain, this provides important information regarding the physiological state of the muscle. These sensations ultimately contribute to what is termed "exercise-induced pain". Despite being well recognized by athletes and coaches, and suggested to be integral to exercise performance, this construct has largely escaped attention in experimental work. This perspective article highlights the current understanding of pacing in endurance performance, and the causes of exercise-induced pain. A new perspective is described, which proposes how exercise-induced pain may be a contributing factor in helping individuals to regulate their work rate during exercise and thus provides an important construct in pacing. Keywords: pain, exercise-induced pain, discomfort, exercise performance, self-paced

Reduced density and altered regulation of rat atrial L-type Ca2+ current in heart failure.

Science.gov (United States)

Bond, Richard C; Bryant, Simon M; Watson, Judy J; Hancox, Jules C; Orchard, Clive H; James, Andrew F

2017-03-01

Constitutive regulation by PKA has recently been shown to contribute to L-type Ca 2+ current ( I CaL ) at the ventricular t-tubule in heart failure. Conversely, reduction in constitutive regulation by PKA has been proposed to underlie the downregulation of atrial I CaL in heart failure. The hypothesis that downregulation of atrial I CaL in heart failure involves reduced channel phosphorylation was examined. Anesthetized adult male Wistar rats underwent surgical coronary artery ligation (CAL, N =10) or equivalent sham-operation (Sham, N =12). Left atrial myocytes were isolated ~18 wk postsurgery and whole cell currents recorded (holding potential=-80 mV). I CaL activated by depolarizing pulses to voltages from -40 to +50 mV were normalized to cell capacitance and current density-voltage relations plotted. CAL cell capacitances were ~1.67-fold greater than Sham ( P ≤ 0.0001). Maximal I CaL conductance ( G max ) was downregulated more than 2-fold in CAL vs. Sham myocytes ( P 50% more effectively in CAL than in Sham so that differences in I CaL density were abolished. Differences between CAL and Sham G max were not abolished by calyculin A (100 nmol/l), suggesting that increased protein dephosphorylation did not account for I CaL downregulation. Treatment with either H-89 (10 μmol/l) or AIP (5 μmol/l) had no effect on basal currents in Sham or CAL myocytes, indicating that, in contrast to ventricular myocytes, neither PKA nor CaMKII regulated basal I CaL Expression of the L-type α 1C -subunit, protein phosphatases 1 and 2A, and inhibitor-1 proteins was unchanged. In conclusion, reduction in PKA-dependent regulation did not contribute to downregulation of atrial I CaL in heart failure. NEW & NOTEWORTHY Whole cell recording of L-type Ca 2+ currents in atrial myocytes from rat hearts subjected to coronary artery ligation compared with those from sham-operated controls reveals marked reduction in current density in heart failure without change in channel subunit

Current rates of publication for podium and poster presentations at the american society for surgery of the hand annual meetings.

Science.gov (United States)

Abzug, Joshua M; Osterman, Meredith; Rivlin, Michael; Paryavi, Ebrahim; Osterman, A Lee

2014-09-01

Research projects are presented at the Annual Meetings of the American Society for Surgery of the Hand (ASSH). It is unknown how many achieve publication in peer-reviewed journals. We sought to determine current rates of publication of podium and poster presentations. All ASSH podium and poster presentations from 2000 to 2005 were reviewed, and an Internet-based search using PubMed and Google was conducted to determine whether the presented studies had been published. Times to publication and journal names were recorded. Data were analyzed with descriptive statistics. Fisher's exact test was conducted to compare current trends with previous trends. Of 1127 podium and poster presentations reviewed, 46% were published in peer-reviewed journals. Forty-seven percent of published presentations (242 presentations) were in Journal of Hand Surgery, and 11% (59 presentations) were in Journal of Bone and Joint Surgery. Forty-five percent of presentations were published within 2 years and 66% within 3 years. The publication rate for podium presentations was significantly higher than that previously reported for Journal of Hand Surgery, at 54% compared with 44% (P=0.004). Currently, fewer than half of the studies presented at Annual Meetings of the ASSH achieve publication in peer-reviewed journals. Presentations are most likely to be published within 3 years, and almost half are published in Journal of Hand Surgery.

Specialized meeting on 'Current topics of reactor safety research in Germany'; Fachtag 'Aktuelle Themen der Reaktorsicherheitsforschung in Deutschland'

Energy Technology Data Exchange (ETDEWEB)

Kruessenberg, Anne

2013-04-15

On October 11 and 12, 2012, the 2-day specialized meeting organized by the Thermodynamics and Fluid Dynamics Group together with the Dresden-Rossendorf Helmholtz Center and TUeV NORD SysTec GmbH and Co.KG was held at the Dresden-Rossendorf Helmholtz Center within the series of events on 'Current Topics of Safety Research in Germany.' The program of lectures was supplemented by poster presentations and exhibitions by the members of the joint research groups and companies working in the fields. The meeting again was very well attended by over 100 persons. (orig.)

Sound insulation performance in Danish multi-storey housing 1850-2009 and upgrade possibilities to meet current regulations

DEFF Research Database (Denmark)

Rasmussen, Birgit; Hoffmeyer, Dan

2013-01-01

to improve sound insulation in multi-storey housing. The paper quantifies dwellings built in different periods of 1850-2009 and summarizes key characteristics of building types and constructions as well as related sound insulation performance, some being far from fulfilling the limits in the latest Danish...... regulations. Sound insulation data from selected building types are presented, and improvement potential and feasibility based on benefits and drawbacks of different solutions are discussed. To include practical experience in development of solutions, several housing associations have been contacted, but even...... when carrying out major refurbishment work, focus is on energy issues, building maintenance and visual qualities, and sound insulation improvement almost never considered. Thus, it is clearly a challenge to change the mind-set of involved parties to apply a more holistic approach and include sound...

Role of plasma membrane-associated AKAPs for the regulation of cardiac IK1 current by protein kinase A.

Science.gov (United States)

Seyler, Claudia; Scherer, Daniel; Köpple, Christoph; Kulzer, Martin; Korkmaz, Sevil; Xynogalos, Panagiotis; Thomas, Dierk; Kaya, Ziya; Scholz, Eberhard; Backs, Johannes; Karle, Christoph; Katus, Hugo A; Zitron, Edgar

2017-05-01

The cardiac I K1 current stabilizes the resting membrane potential of cardiomyocytes. Protein kinase A (PKA) induces an inhibition of I K1 current which strongly promotes focal arrhythmogenesis. The molecular mechanisms underlying this regulation have only partially been elucidated yet. Furthermore, the role of A-kinase anchoring proteins (AKAPs) in this regulation has not been examined to date. The objective of this project was to elucidate the molecular mechanisms underlying the inhibition of I K1 by PKA and to identify novel molecular targets for antiarrhythmic therapy downstream β-adrenoreceptors. Patch clamp and voltage clamp experiments were used to record currents and co-immunoprecipitation, and co-localization experiments were performed to show spatial and functional coupling. Activation of PKA inhibited I K1 current in rat cardiomyocytes. This regulation was markedly attenuated by disrupting PKA-binding to AKAPs with the peptide inhibitor AKAP-IS. We observed functional and spatial coupling of the plasma membrane-associated AKAP15 and AKAP79 to Kir2.1 and Kir2.2 channel subunits, but not to Kir2.3 channels. In contrast, AKAPyotiao had no functional effect on the PKA regulation of Kir channels. AKAP15 and AKAP79 co-immunoprecipitated with and co-localized to Kir2.1 and Kir2.2 channel subunits in ventricular cardiomyocytes. In this study, we provide evidence for coupling of cardiac Kir2.1 and Kir2.2 subunits with the plasma membrane-bound AKAPs 15 and 79. Cardiac membrane-associated AKAPs are a functionally essential part of the regulatory cascade determining I K1 current function and may be novel molecular targets for antiarrhythmic therapy downstream from β-adrenoreceptors.

Design and implementation of a bidirectional current-controlled voltage-regulated DC-DC switched-mode converter

CSIR Research Space (South Africa)

Coetzer, A

2016-01-01

Full Text Available The design and implementation of a bidirectional current-controlled voltage-regulated DC-DC converter is presented. The converter is required to connect a battery of electrochemical cells (the battery) to an asynchronous motor-drive unit via a...

80th Annual Meeting | Annual Meetings | Events | Indian Academy of ...

Indian Academy of Sciences (India)

Current status and future prospects of neutrino mass measurement. View presentation ... Business Meeting of Fellows. 17.00. High Tea ... Hints of 'Beyond Standard Model' cosmology in the cosmic microwave background. View presentation.

29 CFR 1209.05 - Closing of meetings; reasons therefor.

Science.gov (United States)

2010-07-01

....05 Labor Regulations Relating to Labor (Continued) NATIONAL MEDIATION BOARD PUBLIC OBSERVATION OF NATIONAL MEDIATION BOARD MEETINGS § 1209.05 Closing of meetings; reasons therefor. (a) Except where the...) (matters specifically exempted from disclosure by statute); (c)(4) (trade secrets and commercial or...

76 FR 53454 - Exposure Modeling Public Meeting; Notice of Public Meeting

Science.gov (United States)

2011-08-26

... Exposure Modeling Public Meeting will be held for presentation and discussion of current issues related to... Exponential Concentration Decline with Application to Riparian-Aquatic Pesticide Ecotoxicity. 4. Pesticide...

Design and construction of constant voltage and current regulated source with proper characteristics to be used in electronics laboratory designs

International Nuclear Information System (INIS)

Peon A, R.

1978-01-01

A regulated direct current feeding source was designed for the Nuclear Energy National Institute Electronics Labortory, with the following characteristics: a) voltage input 105-130V a.c. 50-60 Hz; b) voltage output 0.40 V d.c.; c) output current 0-2 Amp d.c.; d) load regulation 0.001%; e) line regulation 0.001%; f) ripple and noise 200 μ Vpp; g) temperature interval 3-60 0 C; h) stability 0.5%; i) output impedance as voltage source 0.01 ohms; j) transient response 50 μ seg. Besides of operating normally, that is as voltage source or current-source through the front controls, the source can be used and interconnected with one or other compatible sources (autoseries, autoparallel and programmed reference). The source will cost 70,000 pesos approximately. (author)

Design of constant current charging power supply for J-TEXT ohmic field capacitor banks

International Nuclear Information System (INIS)

Lv Shudong; Zhang Ming; Rao Bo; Yu Kexun; Yang Cheng

2014-01-01

The charging characteristic of the capacitor charging power supply was analyzed with practical series resonant topology. The method that setting two current taps and regulating PWM switching frequency was putted forward with close loop controlling algorithm to charge the multi-group capacitor banks with constant current. A capacitor charging power supply with the max output current 6.5 A and the max output voltage 2000 V is designed. Experimental results show that, this power supply can charge the four capacitor banks to any four different voltages in 1 minute with charging accuracy less than 1%, and meet the requirements of J-TEXT ohmic field power system. (authors)

77 FR 39749 - Sunshine Act Meeting

Science.gov (United States)

2012-07-05

... advertising in securities offerings conducted pursuant to Rule 506 of Regulation D under the Securities Act... Startups Act. At times, changes in Commission priorities require alterations in the scheduling of meeting...

Is There an Opportunity for Current Chemotherapeutics to Up-regulate MIC-A/B Ligands?

Directory of Open Access Journals (Sweden)

Kendel Quirk

2017-10-01

Full Text Available Natural killer (NK cells are critical effectors of the immune system. NK cells recognize unhealthy cells by specific ligands [e.g., MHC- class I chain related protein A or B (MIC-A/B] for further elimination by cytotoxicity. Paradoxically, cancer cells down-regulate MIC-A/B and evade NK cell’s anticancer activity. Recent data indicate that cellular-stress induces MIC-A/B, leading to enhanced sensitivity of cancer cells to NK cell-mediated cytotoxicity. In this Perspective article, we hypothesize that current chemotherapeutics at sub-lethal, non-toxic dose may promote cellular-stress and up-regulate the expression of MIC-A/B ligands to augment cancer’s sensitivity to NK cell-mediated cytotoxicity. Preliminary data from two human breast cancer cell lines, MDA-MB-231 and T47D treated with clinically relevant therapeutics such as doxorubicin, paclitaxel and methotrexate support the hypothesis. The goal of this Perspective is to underscore the prospects of current chemotherapeutics in NK cell immunotherapy, and discuss potential challenges and opportunities to improve cancer therapy.

Circumpolar biodiversity monitoring program (CBMP): Coastal expert workshop meeting report

Science.gov (United States)

Anderson, Rebecca D.; McLennan, Donald; Thomson, Laura; Wegeberg, Susse; Pettersvik Arvnes, Maria; Sergienko, Liudmila; Behe, Carolina; Moss-Davies, Pitseolak; Fritz, Stacey; Christensen, Thomas K.; Price, Courtney

2016-01-01

The Coastal Expert Workshop, which took place in Ottawa, Canada from March 1 to 3, 2016, initiated the development of the Arctic Coastal Biodiversity Monitoring Plan (Coastal Plan). Meeting participants, including northern residents, representatives from industry, non-governmental organisations (NGOs), academia, and government regulators and agencies from across the circumpolar Arctic, discussed current biodiversity monitoring efforts, key issues facing biodiversity in Arctic coastal areas, and collectively identified monitoring indicators, or Focal Ecosystem Components (FECs). On February 29, the day before the workshop, a full day was allocated to Traditional Knowledge (TK) holders to meet and elucidate how this important knowledge can be included in the process of building the Coastal Plan and monitoring biodiversity in Arctic coastal areas, along with scientific data and variables. This document provides 1) background information about the Circumpolar Biodiversity Monitoring Programme and the Coastal Expert Monitoring Group, 2) overviews on workshop presentations and breakout sessions, and 3) details regarding outcomes of the workshop that will inform the drafting of the Coastal Plan.

Workshop meeting on State accounting and control system for radioactive substances and waste

International Nuclear Information System (INIS)

Evseev, V.F.

2012-01-01

On 2-6 July 2012, the fifth All-Russian workshop meeting of State Accounting and Control System for Radiation Substances (RS) and Radioactive Wastes (RAW) was conducted. The objective of the workshop was to discuss development of the State Accounting and Control System for RS and RAW in the Russian Federation, current changes to legal acts and regulations that pertain to management of RS and RAW, as well as other issues related to organisation of RS and RAW management activities and promotion of international cooperation [ru

77 FR 49462 - National Science Board; Sunshine Act Meetings

Science.gov (United States)

2012-08-16

... NATIONAL SCIENCE FOUNDATION National Science Board; Sunshine Act Meetings The National Science Board, pursuant to NSF regulations (45 CFR Part 614), the National Science Foundation Act, as amended... regard to the scheduling of a teleconference meeting of the Audit and Oversight Committee for the...

ELECTRONIC FUNDS TRANSFER IN MONEY LAUNDERING CRIME: REGULATION NEEDED IN RESPONSE TO MEETING OF TECHNOLOGY AND CRIME IN INDONESIA

Directory of Open Access Journals (Sweden)

Go Lisanawati

2010-12-01

Full Text Available Advancements in information technology have affected modern society in numerous areas, including communication, education, commerce, and so on. These advancements have brought incredible benefits; they have also provided opportunities and motivation for various forms of crime. Information technology has also made crime highly profitable. Among the many types of criminal activities, modern technology has allowed money laundering to become an online crime. This new type of crime has raised some legal questions about the capability of national and international regulations in relation to current and upcoming issues. These include finding electronic funds transfer records after the fact, and determining money laundering activity that includes electronic funds transfer. Although Indonesia is an integral member of a community concerned with the interaction between technology and money laundering, it has not provided regulations to deal with the current and upcoming issues involving the crime of electronic money laundering. The increase in the amount of crime indicates the following series of techniques and mechanisms that had been detected in relation to money laundering activity. This research will examine current issues under the light of Indonesian regulations, and will put forward some proposals to close the legal vacuum.

76 FR 13617 - Depository Library Council to the Public Printer Meeting

Science.gov (United States)

2011-03-14

... GOVERNMENT PRINTING OFFICE Depository Library Council to the Public Printer Meeting The Depository Library Council to the Public Printer (DLC) will meet on Monday, April 4, 2011 through Wednesday, April 6... Disabilities Act and meets all Fire Safety Act regulations. William J. Boarman, Public Printer of the United...

Improving nuclear regulation. Compilation of Nea regulatory guidance booklets

International Nuclear Information System (INIS)

2009-01-01

A common theme throughout the series of NEA regulatory guidance reports, or 'green booklets', is the premise that the fundamental objective of all nuclear safety regulatory bodies is to ensure that nuclear facilities are operated at all times and later decommissioned in an acceptably safe manner. In meeting this objective the regulator must keep in mind that it is the operator that has responsibility for safely operating a nuclear facility; the role of the regulator is to oversee the operator's activities as related to assuming that responsibility. For the first time, the full series of these reports have been brought together in one edition. As such, it is intended to serve as a knowledge management tool both for current regulators and the younger generation of nuclear experts entering the regulatory field. While the audience for this publication is primarily nuclear regulators, the information and ideas may also be of interest to nuclear operators, other nuclear industry organisations and the general public. (author)

Current Rates of Publication for Podium and Poster Presentations at the American Society for Surgery of the Hand Annual Meetings

Directory of Open Access Journals (Sweden)

Joshua M. Abzug

2014-09-01

Full Text Available Background:  Research projects are presented at the Annual Meetings of the American Society for Surgery of the Hand (ASSH. It is unknown how many achieve publication in peer-reviewed journals. We sought to determine current rates of publication of podium and poster presentations.   Methods:  All ASSH podium and poster presentations from 2000 to 2005 were reviewed, and an Internet-based search using PubMed and Google was conducted to determine whether the presented studies had been published. Times to publication and journal names were recorded. Data were analyzed with descriptive statistics. Fisher’s exact test was conducted to compare current trends with previous trends. Results:  Of 1127 podium and poster presentations reviewed, 46% were published in peer-reviewed journals. Forty-seven percent of published presentations (242 presentations were in Journal of Hand Surgery , and 11% (59 entations were in Journal of Bone and Joint Surgery . Forty-five percent of presentations were published within 2 years and 66% within 3 years. The publication rate for podium presentations was significantly higher than that previously reported for Journal of Hand Surgery, at 54% compared with 44% (P=0.004.  Conclusions:  Currently, fewer than half of the studies presented at Annual Meetings of the ASSH achieve publication in peer-eviewed journals. Presentations are most likely to be published within 3 years, and almost half are published in Journal of Hand Surgery .

UK medicines regulation: responding to current challenges.

Science.gov (United States)

Richards, Natalie; Hudson, Ian

2016-12-01

The medicines regulatory environment is evolving rapidly in response to the changing environment. Advances in science and technology have led to a vast field of increasingly complicated pharmaceutical and medical device products; increasing globalization of the pharmaceutical industry, advances in digital technology and the internet, changing patient populations, and shifts in society also affect the regulatory environment. In the UK, the Medicines and Healthcare products Regulatory Agency (MHRA) regulates medicines, medical devices and blood products to protect and improve public health, and supports innovation through scientific research and development. It works closely with other bodies in a single medicines network across Europe and takes forward UK health priorities. This paper discusses the range of initiatives in the UK and across Europe to support innovation in medicines regulation. The MHRA leads a number of initiatives, such as the Innovation Office, which helps innovators to navigate the regulatory processes to progress their products or technologies; and simplification of the Clinical Trials Regulations and the Early Access to Medicines Scheme, to bring innovative medicines to patients faster. The Accelerated Access Review will identify reforms to accelerate access for National Health Service patients to innovative medicines and medical technologies. PRIME and Adaptive Pathways initiatives are joint endeavours within the European regulatory community. The MHRA runs spontaneous reporting schemes and works with INTERPOL to tackle counterfeiting and substandard products sold via the internet. The role of the regulator is changing rapidly, with new risk-proportionate, flexible approaches being introduced. International collaboration is a key element of the work of regulators, and is set to expand. © 2016 The British Pharmacological Society.

Discussing compliance. Summary report from discussions with Robert Bernero and Chris Whipple regarding compliance with the Swedish HLW Regulations from meetings in Stockholm May 3 and 4, 1999

Energy Technology Data Exchange (ETDEWEB)

Jensen, Mikael

1999-06-01

Summary report from discussions with Robert Bernero and Chris Whipple regarding compliance with the Swedish HLW Regulations from meetings in Stockholm. The report also contains bibliographical information and preliminary observations made by Robert Bernero and Chris Whipple.

Discussing compliance. Summary report from discussions with Robert Bernero and Chris Whipple regarding compliance with the Swedish HLW Regulations from meetings in Stockholm May 3 and 4, 1999

International Nuclear Information System (INIS)

Jensen, Mikael

1999-06-01

Summary report from discussions with Robert Bernero and Chris Whipple regarding compliance with the Swedish HLW Regulations from meetings in Stockholm. The report also contains bibliographical information and preliminary observations made by Robert Bernero and Chris Whipple

A fast transient response low dropout regulator with current control methodology

Energy Technology Data Exchange (ETDEWEB)

Ma Zhuo; Guo Yang; Duan Zhikui; Xie Lunguo; Chen Jihua; Yu Jinshan, E-mail: guoyang@nudt.edu.cn [School of Computer, National University of Defense Technology, Changsha 410073 (China)

2011-08-15

A transient performance optimized CCL-LDO regulator is proposed. In the CCL-LDO, the control method of the charge pump phase-locked loop is adopted. A current control loop has the feedback signal and reference current to be compared, and then a loop filter generates the gate voltage of the power MOSFET by integrating the error current. The CCL-LDO has the optimized damping coefficient and natural resonant frequency, while its output voltage can be sub-1-V and is not restricted by the reference voltage. With a 1 {mu}F decoupling capacitor, the experimental results based on a 0.13 {mu}m CMOS process show that the output voltage is 1.0 V; when the workload changes from 100 {mu}A to 100 mA transiently, the stable dropout is 4.25 mV, the settling time is 8.2 {mu}s and the undershoot is 5.11 mV; when the workload changes from 100 mA to 100 {mu}A transiently, the stable dropout is 4.25 mV, the settling time is 23.3 {mu}s and the overshoot is 6.21 mV. The PSRR value is more than -95 dB. Most of the attributes of the CCL-LDO are improved rapidly with a FOM value of 0.0097.

A fast transient response low dropout regulator with current control methodology

International Nuclear Information System (INIS)

Ma Zhuo; Guo Yang; Duan Zhikui; Xie Lunguo; Chen Jihua; Yu Jinshan

2011-01-01

A transient performance optimized CCL-LDO regulator is proposed. In the CCL-LDO, the control method of the charge pump phase-locked loop is adopted. A current control loop has the feedback signal and reference current to be compared, and then a loop filter generates the gate voltage of the power MOSFET by integrating the error current. The CCL-LDO has the optimized damping coefficient and natural resonant frequency, while its output voltage can be sub-1-V and is not restricted by the reference voltage. With a 1 μF decoupling capacitor, the experimental results based on a 0.13 μm CMOS process show that the output voltage is 1.0 V; when the workload changes from 100 μA to 100 mA transiently, the stable dropout is 4.25 mV, the settling time is 8.2 μs and the undershoot is 5.11 mV; when the workload changes from 100 mA to 100 μA transiently, the stable dropout is 4.25 mV, the settling time is 23.3 μs and the overshoot is 6.21 mV. The PSRR value is more than -95 dB. Most of the attributes of the CCL-LDO are improved rapidly with a FOM value of 0.0097.

A study on how to divide and recodify the atomic energy act and its related regulations

Energy Technology Data Exchange (ETDEWEB)

Lee, Kyung Hui; Chung, Sang Ki; Lee, Sang Soo [Hannam Univ., Taejon (Korea, Republic of); Myung, Jae Jin [Chungnam National Univ., Taejon (Korea, Republic of)

2003-02-15

As a part of big project named 'streamlining and optimization of nuclear safety regulatory system', this report focuses on how to divide and recodify the Atomic Energy Act and its related regulations. Follow the first chapter of preface, the second chapter shows the systemic problems of regulation of current AEA and out strategy to reform and re-systematize it. This report concludes that the regulations of the current AEA need to be divided in three parts, i.e. the presidential regulations of FWAAE, NNA and RPA and the ministerial regulation of AEA in two part, i.e. that of NNA and RPA. Then the problems of current regulations of AEA are pointed out and the alternative regulations of FWAAE and NNA are persented in the third and forth chapter respectively. In the fifth chapter RPA is persented. And finally the legal character of several nuclear safety standards is estimated. Concerning nuclear safety or technology standards, those issued by Minister of Science and Technology (MST) empowered by law or its regulation is obviously forceful as a law. But the standards made by KINS to meet the tasks entrusted to KINS by MST is only conditionally forceful as a law, that is, on the condition that law or regulation empowered the chief of KINS to make nuclear safety and/or technology standards.

77th Annual Meeting | Annual Meetings | Events | Indian Academy of ...

Indian Academy of Sciences (India)

... Proceedings – Mathematical Sciences · Resonance – Journal of Science Education · Sadhana · Current Science ... Venue : Physical Research Laboratory, Ahmedabad ... K. R. GOPIDAS, National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram ... Business Meeting of Fellows (Seminar Hall).

Anti-cyclic regulation of the Ukrainian economy under current conditions of the international markets volatility

Directory of Open Access Journals (Sweden)

Volodymyr Satsyk

2009-04-01

Full Text Available In the article there are considered the theoretical and methodological basis of anti-cyclic regulation of the countries’ economy under conditions of the world economy globalization. It suggests the analysis of practices of implementing of anti-cyclic policy in highly developed states, its defining features and directions under current global financial and economic crisis. There has been researched a practical toolkit of economic cycles diagnostics and cyclic fluctuations of total business activity in Ukraine based on this study. There are suggested recommendations concerning the formation of the effective mechanism of anti-cyclic regulation of the Ukrainian economy.

STANDING CONCERTATION COMMITTEE ORDINARY MEETING ON 25 APRIL & 9 MAY 2001

CERN Multimedia

2001-01-01

This meeting was mainly devoted to preparing the next meeting of TREF in May and to discussion of status reports from several Sub-Groups of the SCC. 1. Preparation for the meeting of TREF on 18 May Main items on the Agenda of this meeting concern the follow-up to the 5-yearly Review 2000 and modifications to the Staff Rules and Regulations. The SCC finalised an information document on the discrepancy in the net salary adjustment on 1 January 2001, as well as proposed modified texts of the Staff Rules and Regulations. These documents are to be submitted to the Finance Committee on 13 June. The modifications to the Staff Rules and Regulations concern adjustments for the implementation of the new career structure and various technical improvements. Other items on TREF's Agenda include status reports on preparation for implementing the new career structure in September and on implementation of detailed provisions concerning Long-Term Care. 2. The new Career Structure At the session of the SCC on 25 April, the Sta...

Nuclear regulations: current status and proposed initiatives

International Nuclear Information System (INIS)

Domondon, D.B.; Valdezco, E.M.; Mateo, A.J.; Parami, V.K.

1996-01-01

The science Act of 1958 created the Philippine Atomic Energy Commission, presently known as the Philippine Nuclear Research Institute (PNRI), under the Department of Science and Technology (DOST). The PNRI is tasked with the dual role of promotion and control of the peaceful applications of atomic energy. To carry its mandate of regulation and control on the use of raioisotopes in various fields, the PNRI had promulgated and issued specific regulations known as the Code of PNRI regulations. This paper summarizes the activities undertaken by PNRI in the continuing process of review and subsequent revisions of the Code of PNRI regulations and related guidance documents. It highlights proposed modifications in the present regulations in an attempt to adopt the new international basic safety standards, the practical problems and related issues attendant to the implementation of these new standards, among others. In line with the overall objective of PNRI to ensure the safe application of nuclear energy and radiation technology in various fields, the institute conducted a series of regulatory information conferences to provide an opportunity for members of the regulatory staff of the PNRI and licenses to discuss safety initiatives and regulatory issues. This paper will also provide an in-depth assessment of the lessons learned from these conferences which were conducted by sector or by specific applications for a more focused approach, e.g. radiopharmaceuticals, industrial radiography, research, among others. Licensees' feedback on the PNRI regulatory process are presented as part of the overall objective of enhancing the operational experiences of the licensing, review and evaluation group as well as that of inspection, enforcement and compliance. Several proposed initiatives for consideration of the PNRI to further strengthen its regulatory functions are also briefly outlined. (author)

The effect of plant growth regulators and their interaction with electric current on winter wheat development

Czech Academy of Sciences Publication Activity Database

Biesaga-Koscielniak, J.; Koscielniak, J.; Filek, M.; Marcinska, I.; Krekule, Jan; Macháčková, Ivana; Kubon, M.

2010-01-01

Roč. 32, č. 5 (2010), s. 987-995 ISSN 0137-5881 Institutional research plan: CEZ:AV0Z50380511 Keywords : In vitro culture * Plant growth regulators * Electric current Subject RIV: EF - Botanics Impact factor: 1.344, year: 2010

The meeting goer's lament.

Science.gov (United States)

Meyer, H

1980-10-22

Executives spend about 69% of their time in meeting with at least two other people, according to a recent study out of McGill University. In spite of this, participants do not consider this to be time used wisely and, according to the respondents, the problem seems to be growing worse. Despite the claims of some executives that government regulations or increased corporate complexity underlies the problem, society at large is viewed as the source of the change. Meyer asserts that all institutions have become less authoritarian and the trend away from command has left persuasion and consensus as the basis for corporate level decision-making. Although executives seem to agree that most time is wasted because participants fail to be succinct, the author argues that leaders could improve meetings by choosing the right participants, guiding them briskly through the agenda, and closing the meeting before it degenerates into a shouting match. The article suggests that chief executives are concluding that meeting skills can be learned. Most of the FORTUNE 500 companies have hired outside experts to teach these skills and some companies are building inhouse units for the same purpose. Since meetings have become an integral part of the business day, Meyer concluded that the goal of the executive should be to use the meeting time well.

Summary report of consultants' meeting - IAEA International Database on Irradiated Nuclear Graphite Properties. 8th meeting of the Technical Steering Committee

International Nuclear Information System (INIS)

Humbert, D.; Wickham, A.J.

2006-05-01

The '8th Meeting of the Technical Steering Committee for the International Database on Irradiated Nuclear Graphite Properties' was held on 15-16 March 2006 at the IAEA Headquarters, Vienna, Austria. All discussions, recommendations and actions of this Consultants' Meeting are recorded in this report. The purposes of the meeting were to review the matters and actions identified in the previous meeting, undertake a review of the current status of the database and make recommendations for actions for the next year. This report contains the current status of the identified actions as well as a summary of the recommendations on enhancements to the database. (author)

Local regulation of interchange turbulence in a dipole-confined plasma torus using current-collection feedback

International Nuclear Information System (INIS)

Roberts, T. M.; Mauel, M. E.; Worstell, M. W.

2015-01-01

Turbulence in plasma confined by a magnetic dipole is dominated by interchange fluctuations with complex dynamics and short spatial coherence. We report the first use of local current-collection feedback to modify, amplify, and suppress these fluctuations. The spatial extent of turbulence regulation is limited to a correlation length near the collector. Changing the gain and phase of collection results in power either extracted from or injected into the turbulence. The measured plasma response shows some agreement with calculations of the linear response of global interchange-like MHD and entropy modes to current-collection feedback

Good Practice Standards – a Regulation Tool

DEFF Research Database (Denmark)

Sørensen, Marie Jull

2013-01-01

The purpose of this article is to identify the considerations weighed in regulation with good practice standards. In this article, potential due process problems with regulation via legal standards are identified and compared to other considerations, which this regulation technique meets....

Eddy current seminar

International Nuclear Information System (INIS)

Emson, C.R.I.

1988-11-01

The paper presents the fifth symposium in the series of Eddy Current Seminars, held in Abingdon, 1988. The meeting included a discussion on three-dimensional eddy current formulations, as well as thirteen contributed papers on computational electromagnetics. Of the thirteen papers, two papers on eddy currents in tokamaks were selected for INIS and indexed separately. (U.K.)

Providing for organizational memory in computer supported meetings

OpenAIRE

Schwabe, Gerhard

1994-01-01

Meeting memory features are poorly integrated into current group support systems (GSS). In this article, I discuss how to introduce meeting memory functionality into a GSS. The article first introduces the benefits of effective meetings and organizational memory to an organization. Then, the following challenges to design are discussed: How to store semantically rich output, how to build up the meeting memory with a minimum of additional effort, how to integrate meeting memory into organizati...

U.S. petroleum refining: Meeting requirements for cleaner fuels and refineries

International Nuclear Information System (INIS)

Warden, R.B.

1993-01-01

A review is presented of a study carried out by the National Petroleum Council that assessed the ability of the U.S. oil industry to manufacture and supply the quantity and quality of products required in the 1990s and beyond. The competitiveness of domestic supply vs product imports was analyzed and the investment requirements and other costs associated with meeting new environmental legislation and regulations on petroleum products and refineries were addressed. In particular, the requirements of the 1990 Clean Air Act Amendments and other environmental, health, and safety initiatives, both current and prospective, were evaluated. Refineries and the logistics system were studied but not crude oil supply or service stations. The costs of stationary source health, safety and environmental regulations and requirements were evaluated for the years 1995, 2000 and 2010, and sources of U.S. light products and U.S. refinery utilization were modelled for these years. Three demand scenarios were considered: growth, no-growth, and decline. Annual expenditures for health, safety and environment programs inside refineries are expected to double in the 1990s. Expenditures of $106 billion are projected over the period 1990-2010 for new facilities and programs necessary for current and anticipated stationary source regulations. Refining and logistics costs will increase substantially. Other conclusions related to capital expenditures, refining capability, product compatibility, oxygenates and foreign product supply cost are drawn. 26 figs

The system of radiation protection: views from the Australian regulator (Arpansa)

International Nuclear Information System (INIS)

Prosser, S.

2004-01-01

Of those issues identified by the EGRP at previous meetings, there are a number of areas where, from the Australian perspective, the current system of radiological protection could benefit from change. These include stakeholder issues, the environment, inconsistencies in numerical values and risk comparison with more common hazards. Implementing any recommended changes would present some bureaucratic challenges but would also provide an opportunity for increasing national uniformity of regulation. However it is recognised that the current system does not provide an unacceptable level of protection and it is therefore important that any proposed changes are thoroughly tested in practice to ensure a real net benefit. (author)

A Low Input Current and Wide Conversion Ratio Buck Regulator with 75% Efficiency for High-Voltage Triboelectric Nanogenerators

Science.gov (United States)

Luo, Li-Chuan; Bao, De-Chun; Yu, Wu-Qi; Zhang, Zhao-Hua; Ren, Tian-Ling

2016-01-01

It is meaningful to research the Triboelectric Nanogenerators (TENG), which can create electricity anywhere and anytime. There are many researches on the structures and materials of TENG to explain the phenomenon that the maximum voltage is stable and the current is increasing. The output voltage of the TENG is high about 180-400 V, and the output current is small about 39 μA, which the electronic devices directly integration of TENG with Li-ion batteries will result in huge energy loss due to the ultrahigh TENG impedance. A novel interface circuit with the high-voltage buck regulator for TENG is introduced firstly in this paper. The interface circuit can transfer the output signal of the TENG into the signal fit to a lithium ion battery. Through the circuit of the buck regulator, the average output voltage is about 4.0 V and the average output current is about 1.12 mA. Further, the reliability and availability for the lithium ion battery and the circuit are discussed. The interface circuit is simulated using the Cadence software and verified through PCB experiment. The buck regulator can achieve 75% efficiency for the High-Voltage TENG. This will lead to a research hot and industrialization applications.

12 CFR 791.6 - Subject matter of a meeting.

Science.gov (United States)

2010-01-01

....6 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING THE OPERATIONS OF THE... REGULATIONS; PUBLIC OBSERVATION OF NCUA BOARD MEETINGS Rules of NCUA Board Procedure § 791.6 Subject matter of... all Office Directors and President of the Central Liquidity Facility), and Regional Directors. [61 FR...

75 FR 8063 - Stakeholder Meeting Regarding Revisions to the Unregulated Contaminant Monitoring Regulation

Science.gov (United States)

2010-02-23

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9116-5] RIN 2040-AF10 Stakeholder Meeting Regarding Revisions... proposed by November 2010. The purpose of this notice is to announce a public stakeholder meeting to present information to stakeholders concerning the status of the Agency's efforts in the areas of analyte...

Is it possible to demonstrate compliance with the regulations for high-level-waste repositories?

International Nuclear Information System (INIS)

Bingham, F.W.

1992-01-01

The regulations that currently govern repositories for spent fuel and high-level waste require demonstrations that are sometimes described as impossible to make. To make them will require an understanding of the current and the future phenomena at repository sites; it will also require credible estimates of the probabilities that the phenomena will occur in the distant future. Experts in many fields emdash earth sciences, statistics, numerical modeling, and the law emdash have questioned whether any amount of data collection can allow modelers to meet these requirements with enough confidence to satisfy the regulators. In recent years some performance assessments have begun to shed light on this question because they use results of actual site investigations. Although these studies do not settle the question definitively, a review of a recent total-system assessment suggests that compliance may be possible to demonstrate. The review also suggests, however, that the demonstration can be only at the ''reasonable'' levels of assurance mentioned, but not defined, in the regulations

A novel flattop current regulated energy discharge type pulsed power supply and magnet yielding 4.4 kGauss-meter for 6 milliseconds

International Nuclear Information System (INIS)

Visser, A.T.

1989-07-01

Most energy discharge power supplies obtain their bursts of power from the energy stored in charged capacitors when it is suddenly released into a load. This note describes the design of a similar small 800 Joules energy discharge type power supply and magnet. The magnet gap is 2 in.x2 in.x25-1/2 in. long and produces about 4.4 kGauss-meters at a rate of 12 pulses per minute. Each pulse is current regulated at the top for a duration of 6 msec. and varies less than 0.6% of set value. Current regulation at flattop is obtained by switching a resistor in and out of the discharge circuit with an IGBT at a rate of about 5 kHz. Most energy discharge systems produce half sine wave pulses, and current regulation is obtained by controlling the charge voltage at the energy storage capacitor, resulting only in a controlled peak current value of the half sine wave pulse. The current value at the top changes substantially during 6 msec. depending on the operating frequency

Protein kinase A and C regulate leak potassium currents in freshly isolated vascular myocytes from the aorta.

Directory of Open Access Journals (Sweden)

Sébastien Hayoz

Full Text Available We tested the hypothesis that protein kinase A (PKA inhibits K2P currents activated by protein kinase C (PKC in freshly isolated aortic myocytes. PDBu, the PKC agonist, applied extracellularly, increased the amplitude of the K2P currents in the presence of the "cocktail" of K(+ channel blockers. Gö 6976 significantly reduced the increase of the K2P currents by PDBu suggesting the involvement of either α or β isoenzymes of PKC. We found that forskolin, or membrane permeable cAMP, did not inhibit K2P currents activated by the PKC. However, when PKA agonists were added prior to PDBu, they produced a strong decrease in the K2P current amplitudes activated by PKC. Inhibition of PDBu-elicited K2P currents by cAMP agonists was not prevented by the treatment of vascular smooth muscle cells with PKA antagonists (H-89 and Rp-cAMPs. Zn(2+ and Hg(2+ inhibited K2P currents in one population of cells, produced biphasic responses in another population, and increased the amplitude of the PDBu-elicited K(+ currents in a third population of myocytes, suggesting expression of several K2P channel types. We found that cAMP agonists inhibited biphasic responses and increase of amplitude of the PDBu-elicited K2P currents produced by Zn(2+ and Hg(2. 6-Bnz-cAMp produced a significantly altered pH sensitivity of PDBu-elicited K2P-currents, suggesting the inhibition of alkaline-activated K2P-currents. These results indicate that 6-Bnz-cAMP and other cAMP analogs may inhibit K2P currents through a PKA-independent mechanism. cAMP analogs may interact with unidentified proteins involved in K2P channel regulation. This novel cellular mechanism could provide insights into the interplay between PKC and PKA pathways that regulate vascular tone.

Meeting the challenges in product specifications

International Nuclear Information System (INIS)

Perez, A.

1999-01-01

The current state of the Canadian petroleum refining industry was discussed with special emphasis on the challenges the industry is facing regarding product specification and relevant public policy. In order to remain competitive and avoid the risk of losing much of its eastern and British Columbia markets to integrated North American supply alternatives, the refining industry has undergone severe restructuring, in the process closing 17 refineries in Canada since 1983. Although there has been an increased emphasis on lower cost feedstocks, processing has become more environmentally challenging. For example, the sulphur content in gasoline must meet stringent specifications. Air quality issues are pushing both vehicle technology and fuel formulation, and both vehicle and fuel manufacturers are looking for global solutions. Proposed Canadian regulations were described as not well geared to dealing with these solutions, i.e. fuel formulation standards are looked at in isolation from from each other, or from vehicle technology advancements. As an example the proposed regulation concerning sulphur in gasoline was cited, alleging that requiring lower levels two years in advance of the next generation of low emission vehicles will create a serious threat to the competitiveness of domestic refiners vis-a-vis their U.S. counterparts. 1 tab., 3 figs

Low-level radioactive waste disposal in the United States: An overview of current commercial regulations and concepts

International Nuclear Information System (INIS)

Kennedy, W.E. Jr.

1993-08-01

Commercial low-level radioactive waste disposal in the United States is regulated by the US Nuclear Regulatory Commission (NRC) under 10 CFR 61 (1991). This regulation was issued in 1981 after a lengthy and thorough development process that considered the radionuclide concentrations and characteristics associated with commercial low-level radioactive waste streams; alternatives for waste classification; alternative technologies for low-level radioactive waste disposal; and data, modeling, and scenario analyses. The development process also included the publication of both draft and final environmental impact statements. The final regulation describes the general provisions; licenses; performance objectives; technical requirements for land disposal; financial assurances; participation by state governments and Indian tribes; and records, reports, tests, and inspections. This paper provides an overview of, and tutorial on, current commercial low-level radioactive waste disposal regulations in the United States

Proceedings of national avian-wind power planning meeting 2

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-02-01

This meeting was the second in a series. The purposes of this meeting were to: (1) provide information on avian/wind power interactions that will help meet the needs of regulators, researchers, and other stakeholders concerned with responsible development and permitting of wind plants; (2) create dialogue among regulators, researchers and other stakeholders to help all parties understand the role that research can play in responsible development and permitting of wind plants, and allow researchers to understand the relevance of their research to the process; and (3) propose research projects and the appropriate sponsorship. The meeting began with oral presentations and discussions of nine White Papers on the theory and methods for studying and understanding impacts. The Proceedings include the written version of each of the nine White Papers, plus a summary of the oral discussion associated with each paper. The second part of the meeting consisted of four working group sessions: (1) site evaluation and pre-permit research and planning; (2) operational monitoring; (3) modeling and forecasting, including population dynamics models; and (4) avian behavior and mortality reduction. The Proceedings includes a summary of the discussions on these topics, including each working group`s recommendations for future research or associated activities. A final plenary session drew together the main recommendations.

Proceedings of national avian-wind power planning meeting II

International Nuclear Information System (INIS)

1998-02-01

This meeting was the second in a series. The purposes of this meeting were to: (1) provide information on avian/wind power interactions that will help meet the needs of regulators, researchers, and other stakeholders concerned with responsible development and permitting of wind plants; (2) create dialogue among regulators, researchers and other stakeholders to help all parties understand the role that research can play in responsible development and permitting of wind plants, and allow researchers to understand the relevance of their research to the process; and (3) propose research projects and the appropriate sponsorship. The meeting began with oral presentations and discussions of nine White Papers on the theory and methods for studying and understanding impacts. The Proceedings include the written version of each of the nine White Papers, plus a summary of the oral discussion associated with each paper. The second part of the meeting consisted of four working group sessions: (1) site evaluation and pre-permit research and planning; (2) operational monitoring; (3) modeling and forecasting, including population dynamics models; and (4) avian behavior and mortality reduction. The Proceedings includes a summary of the discussions on these topics, including each working group's recommendations for future research or associated activities. A final plenary session drew together the main recommendations

12 CFR 407.3 - Procedures applicable to regularly scheduled meetings.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Procedures applicable to regularly scheduled meetings. 407.3 Section 407.3 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES REGULATIONS GOVERNING PUBLIC OBSERVATION OF EX-IM BANK MEETINGS § 407.3 Procedures applicable to regularly scheduled...

The 90s - The decade of the environment meeting the training challenge

International Nuclear Information System (INIS)

Worley, T.

1991-01-01

The decade of the 90s is the Decade of the Environment--you see it on TV, in papers, magazines... everywhere. Protection of the environment and compliance with new and ever-changing regulations are a must for companies to be successful. Like all other industries, utilities must meet this challenge head on. The nuclear industry has always been aware of the need for training on nuclear issues such as handling nuclear materials and wastes and responding to nuclear emergencies; but to meet the challenges of tomorrow, we must now provide quality training on environmental regulations. This paper outlines the process Duke Power is using to meet the challenge of providing consistent, accurate, relevant training on EPA, OSHA, and DOT regulations. Training programs discussed in this paper include: general employee environmental overview training; RCRA specific training topics; OSHA emergency response team training; and department of transportation training

76 FR 22939 - Sunshine Act Meeting

Science.gov (United States)

2011-04-25

... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting Notice is hereby given, pursuant to the provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange... Swap,'' ``Security-Based Swap Agreement,'' the regulation of mixed swaps, and books and records...

77 FR 67860 - Sunshine Act Meeting

Science.gov (United States)

2012-11-14

.... Performance and Compensation 5. Report of the Audit, Risk, and Regulation Committee A. Assistant Corporate... management will answer questions from the news media following the Board meeting. STATUS: Open. Agenda..., Rates, and Portfolio Committee A. Financial Performance Update B. Section 13 Tax Equivalent Payments C...

Carbohydrate Metabolism in Archaea: Current Insights into Unusual Enzymes and Pathways and Their Regulation

Science.gov (United States)

Esser, Dominik; Rauch, Bernadette

2014-01-01

SUMMARY The metabolism of Archaea, the third domain of life, resembles in its complexity those of Bacteria and lower Eukarya. However, this metabolic complexity in Archaea is accompanied by the absence of many “classical” pathways, particularly in central carbohydrate metabolism. Instead, Archaea are characterized by the presence of unique, modified variants of classical pathways such as the Embden-Meyerhof-Parnas (EMP) pathway and the Entner-Doudoroff (ED) pathway. The pentose phosphate pathway is only partly present (if at all), and pentose degradation also significantly differs from that known for bacterial model organisms. These modifications are accompanied by the invention of “new,” unusual enzymes which cause fundamental consequences for the underlying regulatory principles, and classical allosteric regulation sites well established in Bacteria and Eukarya are lost. The aim of this review is to present the current understanding of central carbohydrate metabolic pathways and their regulation in Archaea. In order to give an overview of their complexity, pathway modifications are discussed with respect to unusual archaeal biocatalysts, their structural and mechanistic characteristics, and their regulatory properties in comparison to their classic counterparts from Bacteria and Eukarya. Furthermore, an overview focusing on hexose metabolic, i.e., glycolytic as well as gluconeogenic, pathways identified in archaeal model organisms is given. Their energy gain is discussed, and new insights into different levels of regulation that have been observed so far, including the transcript and protein levels (e.g., gene regulation, known transcription regulators, and posttranslational modification via reversible protein phosphorylation), are presented. PMID:24600042

76 FR 55368 - Notice of Commission Meeting and Public Hearing

Science.gov (United States)

2011-09-07

... special public meeting to be held on October 21, 2011 at 1 p.m. in the Patriots Theater at the War... the draft regulations through April 15, 2011 and received oral comment during six public hearing... ten days prior to the meeting date. Additional public records relating to the dockets may be examined...

2004 Children's Health Protection Advisory Committee Meeting Agendas

Science.gov (United States)

Objectives for the three meetings in 2004 include discussing schools-related work, mercury regulation, the Food Quality Protection Act, Children's Health Indicators, early life exposure to carcinogens, and smart growth.

STANDING CONCERTATION COMMITTEE OCTOBER 1999 ORDINARY MEETING

CERN Document Server

1999-01-01

Original: FrenchThe meeting was mainly devoted to the examination of the items below, to which the Committee had allocated two meetings:Preparation for the meeting of TREF on 19 November 1999The SCC took note of the agenda for that meeting which includes additional information on the long-term care insurance project, a second report on staff recruitment and retention, a status report on the voluntary programmes (especially an assessment of the Progressive Retirement Programme), a proposal for the application of the cost-of-living index for 2000, an addendum to the technical amendments to be made to the Staff Rules and Regulations, a balance sheet of CERN's apprenticeship programmes and a status report with regard to guarantees for the pensions of members of the personnel in the event of the dissolution of the Organization.Long-term care: TREF would be given further information following the comments made when the Management's initial proposals were presented to the Forum at its September meeting. The informat...

A 3 A sink/source current fast transient response low-dropout Gm driven linear regulator

International Nuclear Information System (INIS)

Chu Xiuqin; Li Qingwei; Lai Xinquan; Yuan Bing; Li Yanming; Zhao Yongrui

2011-01-01

A 3 A sink/source G m -driven CMOS low-dropout regulator (LDO), specially designed for low input voltage and low cost, is presented by utilizing the structure of a current mirror G m (transconductance) driving technique, which provides high stability as well as a fast load transient response. The proposed LDO was fabricated by a 0.5 μm standard CMOS process, and the die size is as small as 1.0 mm 2 . The proposed LDO dissipates 220 μA of quiescent current in no-load conditions and is able to deliver up to 3 A of load current. The measured results show that the output voltage can be resumed within 2 μs with a less than 1 mV overshoot and undershoot in the output current step from -1.8 to 1.8 A with a 0.1 μs rising and falling time at three 10 μF ceramic capacitors. (semiconductor integrated circuits)

75 FR 61760 - Depository Library Council to the Public Printer; Meeting

Science.gov (United States)

2010-10-06

... GOVERNMENT PRINTING OFFICE Depository Library Council to the Public Printer; Meeting The Depository Library Council to the Public Printer (DLC) will meet on Monday, October 18, 2010, through... regulations. Robert C. Tapella, Public Printer of the United States. [FR Doc. 2010-25047 Filed 10-5-10; 8:45...

Meeting of the high committee for nuclear safety transparency and information. Proceedings of the June 18, 2008 meeting

International Nuclear Information System (INIS)

2008-01-01

The high committee for the nuclear safety transparency and information (HCTISN) is an information, consultation and debate authority devoted to the assessment of the risks linked with nuclear activities and to the analysis of their impact on public health, on the environment and on nuclear safety. Each year, the HCTISN organizes several ordinary meetings in order to analyze some specific topics of the moment. This meeting was organized around 3 main topics: 1 - the organization and stakes of nuclear safety and radiation protection in France, 2 - the plutonium imports and transports from England to France and their conformability with respect to the maritime, nuclear safety and nuclear security regulations, 3 - the role and operation of the HCTISN. This document is the proceedings of this meeting. (J.S.)

International Meeting on Languages, Applied Linguistics and Translation

OpenAIRE

Guerra, Luis

2012-01-01

This meeting aims at providing an overview of the current theory and practice, exploring new directions and emerging trends, sharing good practice, and exchanging information regarding foreign languages, applied linguistics and translation. The meeting is an excellent opportunity for the presentation of current or previous language learning and translation projects funded by the European Commission or by other sources. Proposals are invited for one or more of the following topics, in any of t...

Strategies to facilitate stakeholder and regulator support for technology deployment

International Nuclear Information System (INIS)

Burford, T.D.

1997-01-01

Implementation and deployment of new and innovative environmental technologies is impossible without regulator, enduser and stakeholder support. Technologies being developed for different needs require different strategies to facilitate this endorsement. Areas addressed will include technologies developed to meet site specific cleanup needs and those developed for multiple site applications. A third area deals with using site specific technologies at previously unidentified locations. In order to expand the application of these technologies to other sites a plan to include potential site regulators and stakeholders early in the development process should be considered. The Subsurface Contaminant Focus Area has developed a Stakeholder Communication Plan. This plan, in addition to lessons learned from current technology development projects that have successfully obtained this type of support, will provide the basis for the information provided in this paper. The object of this paper is to suggest strategies that could facilitate the implementation and deployment of technologies at environmental sites by involving regulators and stakeholders at the proper time for various applications

Regional Disease Surveillance Meeting - Final Paper

Energy Technology Data Exchange (ETDEWEB)

Lesperance, Ann M.; Mahy, Heidi A.

2006-08-08

On June 1, 2006, public health officials working in surveillance, epidemiological modeling, and information technology communities from the Seattle/Tacoma area and State of Washington met with members of the Pacific Northwest National Laboratory (PNNL) to discuss the current state of disease surveillance and gaps and needs to improve the current systems. The meeting also included a discussion of PNNL initiatives that might be appropriate to enhance disease surveillance and the current tools being used for disease surveillance. Participants broke out into two groups to identify critical gaps and needs for improving a surveillance system, and discuss the requirements for developing improved surveillance. Each group developed a list of key priorities summarizing the requirements for improved surveillance. The objective of this meeting was to work towards the development of an improved disease surveillance system.

Interlink Converter with Linear Quadratic Regulator Based Current Control for Hybrid AC/DC Microgrid

Directory of Open Access Journals (Sweden)

Dwi Riana Aryani

2017-11-01

Full Text Available A hybrid alternate current/direct current (AC/DC microgrid consists of an AC subgrid and a DC subgrid, and the subgrids are connected through the interlink bidirectional AC/DC converter. In the stand-alone operation mode, it is desirable that the interlink bidirectional AC/DC converter manages proportional power sharing between the subgrids by transferring power from the under-loaded subgrid to the over-loaded one. In terms of system security, the interlink bidirectional AC/DC converter takes an important role, so proper control strategies need to be established. In addition, it is assumed that a battery energy storage system is installed in one subgrid, and the coordinated control of interlink bidirectional AC/DC converter and battery energy storage system converter is required so that the power sharing scheme between subgrids becomes more efficient. For the purpose of designing a tracking controller for the power sharing by interlink bidirectional AC/DC converter in a hybrid AC/DC microgrid, a droop control method generates a power reference for interlink bidirectional AC/DC converter based on the deviation of the system frequency and voltages first and then interlink bidirectional AC/DC converter needs to transfer the power reference to the over-loaded subgrid. For efficiency of this power transferring, a linear quadratic regulator with exponential weighting for the current regulation of interlink bidirectional AC/DC converter is designed in such a way that the resulting microgrid can operate robustly against various uncertainties and the power sharing is carried out quickly. Simulation results show that the proposed interlink bidirectional AC/DC converter control strategy provides robust and efficient power sharing scheme between the subgrids without deteriorating the secure system operation.

12 CFR 407.6 - Transcripts, recordings and minutes of closed meetings.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Transcripts, recordings and minutes of closed meetings. 407.6 Section 407.6 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES REGULATIONS GOVERNING PUBLIC OBSERVATION OF EX-IM BANK MEETINGS § 407.6 Transcripts, recordings and minutes of closed...

Fifth technical meeting on quality

International Nuclear Information System (INIS)

Girard, A.

1998-01-01

This article reports on the 5th Technical Meeting on Quality which was held in San Diego on 20-22 October 1997 and which was attended by representatives of the Home and Joint Central Team and of manufacturers currently involved in the Large R and D projects. The meeting made progress towards the finalization of the ITER Quality Manual document for inclusion in the Final Design Report and the definition of the quality necessary for ITER procurement and construction

78 FR 23899 - Codex Alimentarius Commission: Meeting of the Codex Alimentarius Commission

Science.gov (United States)

2013-04-23

... information to regulations, directives, and notices. Customers can add or delete subscriptions themselves, and... meeting on June 18, 2013. The objective of the public meeting is to provide information and receive public... Rome, Italy. The Under Secretary for Food Safety recognizes the importance of providing interested...

Towards a Virtual General Meeting: ‘I accept’ or ‘I decline’?

NARCIS (Netherlands)

Pemmelaar, Wanne M.

2008-01-01

The General Meeting plays an essential role in the functioning of the Dutch corporate governance system which is based on self-regulation. It is therefore of importance that shareholders turn up during the Annual General Meeting (AGM). However, studies conducted in 2007 showed that on average only

Investigating Relationships among Pre-Service Science Teachers' Conceptual Knowledge of Electric Current, Motivational Beliefs and Self-Regulation

Science.gov (United States)

Inaltun, Hüseyin; Ates, Salih

2015-01-01

The purpose of this study is to examine relationships among pre-service science teachers' conceptual knowledge of electric current, motivational beliefs, and self-regulation. One hundred and twenty-seven students (female = 107, male = 20) enrolled in the science education program of a public university in Ankara participated the study. A concept…

75 FR 21641 - Infusion Pumps; Public Meeting; Request for Comments

Science.gov (United States)

2010-04-26

...] Infusion Pumps; Public Meeting; Request for Comments AGENCY: Food and Drug Administration, HHS. ACTION... announcing a public meeting regarding external infusion pumps. The purpose of the meeting is to inform the public about current problems associated with external infusion pump use, to help the agency identify...

78 FR 40726 - National Telecommunications and Information Administration Multistakeholder Meeting To Develop...

Science.gov (United States)

2013-07-08

... application transparency. For additional information, please see the Multistakeholder Meeting Notice. [[Page...-application-transparency , for the most current information. Place: The rescheduled meeting will be held in...-process-mobile-application-transparency , for the most current information. Dated: July 2, 2013. Kathy...

Third meeting of the advisory group for the comprehensive review of the IAEA regulations for the safe transport of radioactive materials, Vienna, 7-11 November 1983

International Nuclear Information System (INIS)

Rawl, R.R.

This meeting was the third and final planned stage in the process to revise the Agency's Regulations for the Safe Transport of Radioactive Materials, Safety Series No. 6. Its task was to consider comments which had been submitted in response to the Agency's circulation of the third draft revision of Safety Series No. 6 and to make any necessary changes to the draft that the Advisory Group felt were necessary

Current Knowledge on the Acute Regulation of Steroidogenesis.

Science.gov (United States)

Selvaraj, Vimal; Stocco, Douglas M; Clark, Barbara J

2018-04-27

How rapid induction of steroid hormone biosynthesis occurs in response to trophic hormone stimulation of steroidogenic cells has been a subject of intensive investigation for approximately six decades. A key observation made very early was that acute regulation of steroid biosynthesis required swift and timely synthesis of a new protein whose role appeared to be involved in the delivery of the substrate for all steroid hormones, cholesterol, from the outer to the inner mitochondrial membrane where the process of steroidogenesis begins. It was quickly learned that this transfer of cholesterol to the inner mitochondrial membrane was the regulated and rate limiting step in steroidogenesis. Following this observation, the quest for this putative regulator protein(s) began in earnest in the late 1950s. This review provides a history of this quest, the candidate proteins that arose over the years, and facts surrounding their rise or decline. Only two have persisted-Translocator Protein (TSPO) and the Steroidogenic Acute Regulatory Protein (StAR). We present a detailed summary of the work that has been published for each of these two proteins, the specific data that has appeared in support of their role in cholesterol transport and steroidogenesis, and the ensuing observations that have arisen in recent years that have refuted the role of TSPO in this process. We believe that the only viable candidate that has been shown to be indispensable is the StAR protein. Lastly, we provide our view on what may be the most important questions concerning the acute regulation of steroidogenesis that need to be asked in future.

Focused transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex modulates specific domains of self-regulation.

Science.gov (United States)

Pripfl, Jürgen; Lamm, Claus

2015-02-01

Recent neuroscience theories suggest that different kinds of self-regulation may share a common psychobiological mechanism. However, empirical evidence for a domain general self-regulation mechanism is scarce. The aim of this study was to investigate whether focused anodal transcranial direct current stimulation (tDCS), facilitating the activity of the dorsolateral prefrontal cortex (dlPFC), acts on a domain general self-regulation mechanism and thus modulates both affective and appetitive self-regulation. Twenty smokers participated in this within-subject sham controlled study. Effects of anodal left, anodal right and sham tDCS over the dlPFC on affective picture appraisal and nicotine craving-cue appraisal were assessed. Anodal right tDCS over the dlPFC reduced negative affect in emotion appraisal, but neither modulated regulation of positive emotion appraisal nor of craving appraisal. Anodal left stimulation did not induce any significant effects. The results of our study show that domain specific self-regulation networks are at work in the prefrontal cortex. Focused tDCS modulation of this specific self-regulation network could probably be used during the first phase of nicotine abstinence, during which negative affect might easily result in relapse. These findings have implications for neuroscience models of self-regulation and are of relevance for the development of brain stimulation based treatment methods for neuropsychiatric disorders associated with self-regulation deficits. Copyright © 2014 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.

β-Secretase BACE1 regulates hippocampal and reconstituted M-currents in a β-subunit-like fashion.

Science.gov (United States)

Hessler, Sabine; Zheng, Fang; Hartmann, Stephanie; Rittger, Andrea; Lehnert, Sandra; Völkel, Meike; Nissen, Matthias; Edelmann, Elke; Saftig, Paul; Schwake, Michael; Huth, Tobias; Alzheimer, Christian

2015-02-25

The β-secretase BACE1 is widely known for its pivotal role in the amyloidogenic pathway leading to Alzheimer's disease, but how its action on transmembrane proteins other than the amyloid precursor protein affects the nervous system is only beginning to be understood. We report here that BACE1 regulates neuronal excitability through an unorthodox, nonenzymatic interaction with members of the KCNQ (Kv7) family that give rise to the M-current, a noninactivating potassium current with slow kinetics. In hippocampal neurons from BACE1(-/-) mice, loss of M-current enhanced neuronal excitability. We relate the diminished M-current to the previously reported epileptic phenotype of BACE1-deficient mice. In HEK293T cells, BACE1 amplified reconstituted M-currents, altered their voltage dependence, accelerated activation, and slowed deactivation. Biochemical evidence strongly suggested that BACE1 physically associates with channel proteins in a β-subunit-like fashion. Our results establish BACE1 as a physiologically essential constituent of regular M-current function and elucidate a striking new feature of how BACE1 impacts on neuronal activity in the intact and diseased brain. Copyright © 2015 the authors 0270-6474/15/353298-14$15.00/0.

Public meeting on radiation safety for industrial radiographerss: remarks, questions and answers at five NRC regional meetings

International Nuclear Information System (INIS)

1978-11-01

Over the past several years thenumber of radiation overexposures experienced in the radiography industry has been higher than for any other single group of NRC licensees. To inform radiography licensees of NRC's concern fo these recurring overexposure incidents, NRC staff representatives met with licensees in a series of five regional meetings. At these meetings the staff presented prepared remarks and answered questions on NRC regulations and operations. The main purposes of the meetings were to express NRC's concern for the high incidence of overexposures, and to open a line of communication between the NRC and radiography licensees in an effort to achieve the common goal of improved radiation safety. The remarks presented by the staff and subjects discussed at these meetings included: the purpose, scope, findings and goals of the NRC inspection program; ways and means of incorporating safety into radiography operations; and case histories of overexposure incidents, with highlights of the causes and possible preventions. At each of the regional meetings the staff received a request for a copy of the prepared remarks and a consolidation of the questions and answers that were discussed. This document includes that information, and a copy is being provided to each organizaion or firm attending the regional meetings. Requests for other copies should be made in accordance with the directions printed inside the front cover of this document

Inward Rectifier K+ Currents Are Regulated by CaMKII in Endothelial Cells of Primarily Cultured Bovine Pulmonary Arteries.

Science.gov (United States)

Qu, Lihui; Yu, Lei; Wang, Yanli; Jin, Xin; Zhang, Qianlong; Lu, Ping; Yu, Xiufeng; Zhong, Weiwei; Zheng, Xiaodong; Cui, Ningren; Jiang, Chun; Zhu, Daling

2015-01-01

Endothelium lines the interior surface of vascular walls and regulates vascular tones. The endothelial cells sense and respond to chemical and mechanical stimuli in the circulation, and couple the stimulus signals to vascular smooth muscles, in which inward rectifier K+ currents (Kir) play an important role. Here we applied several complementary strategies to determine the Kir subunit in primarily cultured pulmonary arterial endothelial cells (PAECs) that was regulated by the Ca2+/calmodulin (CaM)-dependent protein kinase II (CaMKII). In whole-cell voltage clamp, the Kir currents were sensitive to micromolar concentrations of extracellular Ba2+. In excised inside-out patches, an inward rectifier K+ current was observed with single-channel conductance 32.43 ± 0.45 pS and Popen 0.27 ± 0.04, which were consistent with known unitary conductance of Kir 2.1. RT-PCR and western blot results showed that expression of Kir 2.1 was significantly stronger than that of other subtypes in PAECs. Pharmacological analysis of the Kir currents demonstrated that insensitivity to intracellular ATP, pinacidil, glibenclamide, pH, GDP-β-S and choleratoxin suggested that currents weren't determined by KATP, Kir2.3, Kir2.4 and Kir3.x. The currents were strongly suppressed by exposure to CaMKII inhibitor W-7 and KN-62. The expression of Kir2.1 was inhibited by knocking down CaMKII. Consistently, vasodilation was suppressed by Ba2+, W-7 and KN-62 in isolated and perfused pulmonary arterial rings. These results suggest that the PAECs express an inward rectifier K+ current that is carried dominantly by Kir2.1, and this K+ channel appears to be targeted by CaMKII-dependent intracellular signaling systems.

Differential roles of two delayed rectifier potassium currents in regulation of ventricular action potential duration and arrhythmia susceptibility.

Science.gov (United States)

Devenyi, Ryan A; Ortega, Francis A; Groenendaal, Willemijn; Krogh-Madsen, Trine; Christini, David J; Sobie, Eric A

2017-04-01

Arrhythmias result from disruptions to cardiac electrical activity, although the factors that control cellular action potentials are incompletely understood. We combined mathematical modelling with experiments in heart cells from guinea pigs to determine how cellular electrical activity is regulated. A mismatch between modelling predictions and the experimental results allowed us to construct an improved, more predictive mathematical model. The balance between two particular potassium currents dictates how heart cells respond to perturbations and their susceptibility to arrhythmias. Imbalances of ionic currents can destabilize the cardiac action potential and potentially trigger lethal cardiac arrhythmias. In the present study, we combined mathematical modelling with information-rich dynamic clamp experiments to determine the regulation of action potential morphology in guinea pig ventricular myocytes. Parameter sensitivity analysis was used to predict how changes in ionic currents alter action potential duration, and these were tested experimentally using dynamic clamp, a technique that allows for multiple perturbations to be tested in each cell. Surprisingly, we found that a leading mathematical model, developed with traditional approaches, systematically underestimated experimental responses to dynamic clamp perturbations. We then re-parameterized the model using a genetic algorithm, which allowed us to estimate ionic current levels in each of the cells studied. This unbiased model adjustment consistently predicted an increase in the rapid delayed rectifier K + current and a drastic decrease in the slow delayed rectifier K + current, and this prediction was validated experimentally. Subsequent simulations with the adjusted model generated the clinically relevant prediction that the slow delayed rectifier is better able to stabilize the action potential and suppress pro-arrhythmic events than the rapid delayed rectifier. In summary, iterative coupling of

Inward Rectifier K+ Currents Are Regulated by CaMKII in Endothelial Cells of Primarily Cultured Bovine Pulmonary Arteries.

Directory of Open Access Journals (Sweden)

Lihui Qu

Full Text Available Endothelium lines the interior surface of vascular walls and regulates vascular tones. The endothelial cells sense and respond to chemical and mechanical stimuli in the circulation, and couple the stimulus signals to vascular smooth muscles, in which inward rectifier K+ currents (Kir play an important role. Here we applied several complementary strategies to determine the Kir subunit in primarily cultured pulmonary arterial endothelial cells (PAECs that was regulated by the Ca2+/calmodulin (CaM-dependent protein kinase II (CaMKII. In whole-cell voltage clamp, the Kir currents were sensitive to micromolar concentrations of extracellular Ba2+. In excised inside-out patches, an inward rectifier K+ current was observed with single-channel conductance 32.43 ± 0.45 pS and Popen 0.27 ± 0.04, which were consistent with known unitary conductance of Kir 2.1. RT-PCR and western blot results showed that expression of Kir 2.1 was significantly stronger than that of other subtypes in PAECs. Pharmacological analysis of the Kir currents demonstrated that insensitivity to intracellular ATP, pinacidil, glibenclamide, pH, GDP-β-S and choleratoxin suggested that currents weren't determined by KATP, Kir2.3, Kir2.4 and Kir3.x. The currents were strongly suppressed by exposure to CaMKII inhibitor W-7 and KN-62. The expression of Kir2.1 was inhibited by knocking down CaMKII. Consistently, vasodilation was suppressed by Ba2+, W-7 and KN-62 in isolated and perfused pulmonary arterial rings. These results suggest that the PAECs express an inward rectifier K+ current that is carried dominantly by Kir2.1, and this K+ channel appears to be targeted by CaMKII-dependent intracellular signaling systems.

An energy-efficient, adiabatic electrode stimulator with inductive energy recycling and feedback current regulation.

Science.gov (United States)

Arfin, Scott K; Sarpeshkar, Rahul

2012-02-01

In this paper, we present a novel energy-efficient electrode stimulator. Our stimulator uses inductive storage and recycling of energy in a dynamic power supply. This supply drives an electrode in an adiabatic fashion such that energy consumption is minimized. It also utilizes a shunt current-sensor to monitor and regulate the current through the electrode via feedback, thus enabling flexible and safe stimulation. Since there are no explicit current sources or current limiters, wasteful energy dissipation across such elements is naturally avoided. The dynamic power supply allows efficient transfer of energy both to and from the electrode and is based on a DC-DC converter topology that we use in a bidirectional fashion in forward-buck or reverse-boost modes. In an exemplary electrode implementation intended for neural stimulation, we show how the stimulator combines the efficiency of voltage control and the safety and accuracy of current control in a single low-power integrated-circuit built in a standard .35 μm CMOS process. This stimulator achieves a 2x-3x reduction in energy consumption as compared to a conventional current-source-based stimulator operating from a fixed power supply. We perform a theoretical analysis of the energy efficiency that is in accord with experimental measurements. This theoretical analysis reveals that further improvements in energy efficiency may be achievable with better implementations in the future. Our electrode stimulator could be widely useful for neural, cardiac, retinal, cochlear, muscular and other biomedical implants where low power operation is important.

An advanced regulator for the helium pressurization systems of the Space Shuttle OMS and RCS

Science.gov (United States)

Wichmann, H.

1973-01-01

The Space Shuttle Orbit Maneuvering System and Reaction Control System are pressure-fed rocket propulsion systems utilizing earth storable hypergolic propellants and featuring engines of 6000 lbs and 900 lbs thrust, respectively. The helium pressurization system requirements for these propulsion systems are defined and the current baseline pressurization systems are described. An advanced helium pressure regulator capable of meeting both OMS and RCS helium pressurization system requirements is presented and its operating characteristics and predicted performance characteristics are discussed.

Analysis of environmental constraints on expanding reserves in current and future reservoirs in wetlands. Final report

Energy Technology Data Exchange (ETDEWEB)

Harder, B.J.

1995-03-01

Louisiana wetlands require careful management to allow exploitation of non-renewable resources without destroying renewable resources. Current regulatory requirements have been moderately successful in meeting this goal by restricting development in wetland habitats. Continuing public emphasis on reducing environmental impacts of resource development is causing regulators to reassess their regulations and operators to rethink their compliance strategies. We examined the regulatory system and found that reducing the number of applications required by going to a single application process and having a coherent map of the steps required for operations in wetland areas would reduce regulatory burdens. Incremental changes can be made to regulations to allow one agency to be the lead for wetland permitting at minimal cost to operators. Operators need cost effective means of access that will reduce environmental impacts, decrease permitting time, and limit future liability. Regulators and industry must partner to develop incentive based regulations that can provide significant environmental impact reduction for minimal economic cost. In addition regulators need forecasts of future E&P trends to estimate the impact of future regulations. To determine future activity we attempted to survey potential operators when this approach was unsuccessful we created two econometric models of north and south Louisiana relating drilling activity, success ratio, and price to predict future wetland activity. Results of the econometric models indicate that environmental regulations have a small but statistically significant effect on drilling operations in wetland areas of Louisiana. We examined current wetland practices and evaluated those practices comparing environmental versus economic costs and created a method for ranking the practices.

The role of morbidity and mortality meetings in interventional radiology

International Nuclear Information System (INIS)

Mok, Philip S.; Tan, Eva Y.; Baerlocher, Mark O.; Athreya, Sriharsha

2012-01-01

Purpose: To understand the current practice of interventional radiology (IR) morbidity and mortality (M and M) meetings among interventional radiologists in Europe, and to develop a set of results-based recommendations to increase the prevalence of IR M and M meetings. Materials and methods: Online electronic surveys were sent to members of the Cardiovascular and Interventional Radiology Society of Europe (CIRSE). Each survey consisted of 18 questions pertaining to IR M and M meetings. Results: A total of 150 CIRSE members responded to the survey. Approximately 47% of respondents held IR M and M meetings in their departments. Among those who held IR M and M meetings, 42% held them monthly and 68% rated the quality of the meetings as good or excellent. Of those who did not have M and M meetings, 94% were interested in incorporating M and M meetings into their future practice. The most common reasons for not holding IR M and M meetings were lack of time (68%) and small IR practice groups (43%). A total of 85% were interested in learning more about IR M and M meetings. The preferred method of education about M and M meetings included annual radiology meetings (44%), peer-reviewed articles in radiology journals (31%), websites (26%), and newsletters (15%). Conclusions: The data demonstrate that although current practice of M and M meetings in European IR departments is limited, the majority of respondents believe that M and M meetings are beneficial to their practice. There is a need for guidelines or standards of practice to incorporate such meetings in IR departments to prevent medical errors, which may ultimately lead to enhanced patient safety and outcomes.

FAIR Data; GDPR - Open Data Meeting @ TUD TPM

OpenAIRE

Boehmer, Jasmin

2018-01-01

Presentation given to academic staff and external researcher at TU Delft Open Data Meeting of Faculty Technology, Policy and Management on 12th March 2018. Topics: Lightweight intro for FAIR data; and the new EU General Data Protection Regulation (GDPR)

76 FR 20323 - Hydrographic Services Review Panel Meeting

Science.gov (United States)

2011-04-12

... most current meeting agenda. Times and agenda topics are subject to change. FOR FURTHER INFORMATION...:// nauticalcharts.noaa.gov/ocslhsro/hsro.htm . SUPPLEMENTARY INFORMATION: The meeting will be open to the public and...) Improve the quality and delivery of navigation products and services; (2) maximize the societal value of...

The effect of self-regulated caffeine use on cognition in young adults.

Science.gov (United States)

Harvanko, Arit M; Derbyshire, Katherine L; Schreiber, Liana R N; Grant, Jon E

2015-03-01

Based on previous observational studies that have suggested self-regulated caffeine use by older adults may enhance reaction time performance and vigilance on cognitive tasks, the current study sought to examine whether this effect held true for young adults as well. One hundred and four young adults from two major metropolitan areas, ages 18-29 years, not meeting the criteria for a current psychiatric disorder, completed several cognitive tasks related to decision-making (Cambridge Gamble Task), response inhibition and reaction time (stop-signal task), and vigilance and reaction time (Rapid Visual Information Processing). Caffeine usage was self-reported using a reliable quantity and frequency questionnaire. Self-reported caffeine usage was not significantly associated with any of the cognitive measures used in this study after controlling for age, gender, cigarette smoking, alcohol use, cannabis use, and gambling frequency. These data suggest that self-regulated caffeine usage may not have a significant impact on reaction time, vigilance, response inhibition, or decision-making in young adults, or that these effects are contingent upon other variables not accounted for in the current study. Copyright © 2015 John Wiley & Sons, Ltd.

[100 years of drinking water regulation. Retrospective review, current situation and prospects].

Science.gov (United States)

Rakhmanin, Yu A; Krasovsky, G N; Egorova, N A; Mikhailova, R I

2014-01-01

There is considered the history of the development of legislative requirements to the regulation of the quality of drinking water in different countries and international organizations during the period from 1912 to the present time. In terms of comparative analysis there is analyzed the current state of regulatory frameworks of the Russian Federation, WHO, EU, Finland, the UK, Singapore, Australia, Japan, China, Nigeria, the United States and Canada in the field of providing favorable conditions of population drinking water use. There has been noted the significant progress in standardization of the content of the biogenic elements and chemical pollution of drinking water in the absence of uniform requirements to the composition and properties of drinking water globally, that is bound to the need to take into account the national peculiarities of drinking water supply within the separate countries. As promising directions for improving regulation of drinking water quality there are noted: the development of new standards for prioritized water pollution, periodic review ofstandards after appearance of the new scientific data on the biological action of substances, the use of the concept of risk, the harmonization of the normative values and the assessment of the possibility of introduction into the practice the one more criterion of profitableness of population water use--the bioenergetic state of the water.

Power-MOSFET Voltage Regulator

Science.gov (United States)

Miller, W. N.; Gray, O. E.

1982-01-01

Ninety-six parallel MOSFET devices with two-stage feedback circuit form a high-current dc voltage regulator that also acts as fully-on solid-state switch when fuel-cell out-put falls below regulated voltage. Ripple voltage is less than 20 mV, transient recovery time is less than 50 ms. Parallel MOSFET's act as high-current dc regulator and switch. Regulator can be used wherever large direct currents must be controlled. Can be applied to inverters, industrial furnaces photovoltaic solar generators, dc motors, and electric autos.

77 FR 2092 - Sunshine Act Meeting Notice

Science.gov (United States)

2012-01-13

...: Thursday, January 19, 2012 Audit Committee Agenda 1. Approval of agenda. 2. Approval of minutes of the Committee's meeting of October 18, 2011. 3. Presentation of the Fiscal Year (FY) 2011 Annual Financial Audit...: 1. Audit Committee 3:15 p.m. 2. Operations & Regulations Committee Friday, January 20, 2012: 1...

76 FR 31943 - Global Positioning System Directorate (Gpsd); Notice of Meeting

Science.gov (United States)

2011-06-02

...); Notice of Meeting ACTION: Notice of Meeting--Public Interface Control Working Group (ICWG) for Signals-in... that the Global Positioning Systems (GPS) Directorate will be hosting a Public Interface Control... the Was/Is Matrix, current versions of the documents, and the official meeting notice will be posted...

IAEA International Database on Irradiated Nuclear Graphite Properties. Summary report of consultants' meeting. 12. meeting of the Technical Steering Committee

International Nuclear Information System (INIS)

Chung, H.K.; Wickham, A.J.

2010-02-01

The 12th Meeting of the Technical Steering Committee for the International Database on Irradiated Nuclear Graphite Properties was held on 12-13 November 2009 at the IAEA Headquarters, Vienna, Austria. All discussions, recommendations and actions of this Consultants' Meeting are recorded in this report. The purposes of the meeting were to review the matters and actions identified in the previous meeting, undertake a review of the current status of the database, and make recommendations for action over the next year. This report contains the status of the identified actions as well as a summary of the recommendations on enhancements to the database. (author)

The 5th Symposium on Post-Transcriptional Regulation of Plant Gene Expression (PTRoPGE)

Energy Technology Data Exchange (ETDEWEB)

Karen S. Browning; Marie Petrocek; Bonnie Bartel

2006-06-01

The 5th Symposium on Post-Transcriptional Regulation of Plant Gene Expression (PTRoPGE) will be held June 8-12, 2005 at the University of Texas at Austin. Exciting new and ongoing discoveries show significant regulation of gene expression occurs after transcription. These post-transcriptional control events in plants range from subtle regulation of transcribed genes and phosphorylation, to the processes of gene regulation through small RNAs. This meeting will focus on the regulatory role of RNA, from transcription, through translation and finally degradation. The cross-disciplinary design of this meeting is necessary to encourage interactions between researchers that have a common interest in post-transcriptional gene expression in plants. By bringing together a diverse group of plant molecular biologist and biochemists at all careers stages from across the world, this meeting will bring about more rapid progress in understanding how plant genomes work and how genes are finely regulated by post-transcriptional processes to ultimately regulate cells.

Spent fuel management: Current status and prospects 1997. Proceedings of a regular advisory group meeting

International Nuclear Information System (INIS)

1998-03-01

Spent fuel management has always been one of the important stages in the nuclear fuel cycle and it is still most vital problems common to all countries with nuclear reactors. It begins with the discharge of spent fuel from a power or a research reactor and ends with its ultimate disposition. Two options exist - an open, once-through cycle with direct disposal of the spent fuel and a closed cycle with reprocessing of the spent fuel, recycling of reprocessed plutonium and uranium in new mixed oxide fuels and disposal of the radioactive waste. Continuous attention is being given by the IAEA to the collection, analysis and exchange of information on spent fuel management. Its role in this area is to provide a forum for exchanging information and to co-ordinate and to encourage closer co-operation among Member States in certain research and development activities that are of common interest. Spent fuel management is recognized as a high priority IAEA activity. The Regular Advisory Group on Spent Fuel Management was established in 1982. The objective of the Regular Advisory Group is to serve as a means of exchanging information on the current status and progress of national programmes on spent fuel management and to provide advice to the IAEA. The results of the last Regular Advisory Group meeting (9-12 September 1997) are reflected in this report. It gives an overview of the status of spent fuel management programmes in a number of countries, a description of the current status and prospects of activities in this field and recommendations of the participants

Metastatic castration-resistant prostate cancer: a current view on drug therapy and alternative tumor cell regulation

Directory of Open Access Journals (Sweden)

R. A. Gafanov

2018-01-01

Full Text Available Prostate cancer (PC is one of the most common causes of death from malignant neoplasms in men in many countries around the world. Transmission of the signal in the androgenic axis of regulation is crucial for the development and progression of PC. Despite the constant dependence on androgen receptor signals in castration resistance, the use of new anti-androgenic drugs invariably leads to the stability  of the ongoing treatment. The interaction of androgen receptor and alternative (phosphoinositide-3-kinases, PI3K pathways in the regulation of cells can be one of the mechanisms of resistance to treatment. In this article, we describe current treatments for metastatic castration-resistant PC and the possible role of the PI3K pathway in the pathogenesis and progression of PC.

Status and risk assessment of the use of transgenic arthropods in plant protection. Proceedings of a technical meeting

International Nuclear Information System (INIS)

2006-03-01

New developments in the modern biotechnology have opened up the possibility of introducing genes into the germline of many insect species, including those of agricultural importance. This technology offers the potential to improve current pest control strategies that incorporate the Sterile Insect Technique (SIT). Potential improvements include the development of strains that (1) produce only male insects for sterilization and release and (2) carry a marker that distinguishes them from wild insects. There are many institutions involved in the development of transgenic insect technology both for studies on basic gene regulation and for the creation of transgenic strains for use in a wide range of insect control programmes. It has been realized that the release into the environment of transgenic insects will not be an easy process considering the current public sensitivities in this area. The fact that insects are mobile and that once released cannot be recalled creates much concern. If fertile transgenic insects were to be released in any type of control programme, then the transgene would enter the wild population through mating. This strategy is fraught with, as yet, unknown risks and it is inconceivable that regulatory approval will be given for such a release in the near future. However, when transgenic strains are integrated into a sterile insect release then the concerns about transmission of the transgene to the wild population disappear as the matings between the released and the wild insects are sterile. This scenario is likely to be the first type of transgenic release. Insects that are currently released in SIT programmes experience no significant regulatory problems, but this will not be the case if the insects that are released are transgenic, even if they are sterile. The meeting Status and Risk Assessment of the Use of Transgenic Arthropods in Plant Protection held in FAO Headquarters, Rome, in April 2002 was the first effort to bring together

78 FR 59425 - Minority Depository Institutions Advisory Committee Meeting

Science.gov (United States)

2013-09-26

...] Minority Depository Institutions Advisory Committee Meeting AGENCY: Office of the Comptroller of the... Office of the Comptroller of the Currency (OCC) announces a meeting of the Minority Depository... discussion of the status of the minority depository institution industry and current topics of interest to...

Total absorption gamma-ray spectroscopy (TAGS): Current status of measurement programmes for decay heat calculations and other applications. Summary report of consultants' meeting

International Nuclear Information System (INIS)

Nichols, A.L.; Nordborg, C.

2009-02-01

A Consultants' Meeting on 'Total Absorption Gamma-ray Spectroscopy (TAGS)' was held on 27-28 January 2009 at the IAEA Headquarters, Vienna, Austria. All presentations, discussions and recommendations of this meeting are contained within this report. The purpose of the meeting was to report and discuss progress and plans to measure total gamma-ray spectra in order to derive mean beta and gamma decay data for decay heat calculations and other applications. This form of review had been recommended by contributors to Subgroup 25 of the OECD-NEA Working Party on International Evaluation Cooperation of the Nuclear Science Committee, for implementation in 2008/09. Hence, relevant specialists were invited to discuss their recently performed and planned TAGS studies, along with experimentalists proposing to assemble and operate such dedicated facilities. Knowledge and quantification of antineutrino spectra is believed to be a significant asset in the non-invasive monitoring of reactor operations and possible application in safeguards, as well as fundamental in the study of neutrino oscillations - these data needs were also debated in terms of appropriate TAGS measurements. A re-assessment of the current request list for TAGS studies is merited and was undertaken in the context of decay heat calculations, and agreement was reached to extend these requirements to the derivation of antineutrino spectra. (author)

Proceedings of a specialist meeting on the anti-seismic design of nuclear installations

International Nuclear Information System (INIS)

1976-01-01

This meeting is composed of 26 papers, grouped into 6 sessions. Session I: Introduction (reports on previous meetings related to seismic issues and mechanical structures for nuclear power plants). Session II: seismology. Session III: soil-foundation interaction. Session IV: structures and equipment; Session V: experimental techniques and instrumentation of power plants. Session VI: Synthesis and regulations. Each session is followed by a general discussion. The meeting is concluded with the chairman's report

34 CFR 350.33 - What cooperation requirements must a Rehabilitation Engineering Research Center meet?

Science.gov (United States)

2010-07-01

... Rehabilitation Engineering Research Center meet? A Rehabilitation Engineering Research Center— (a) Shall... 34 Education 2 2010-07-01 2010-07-01 false What cooperation requirements must a Rehabilitation Engineering Research Center meet? 350.33 Section 350.33 Education Regulations of the Offices of the Department...

Meeting of the Pension Fund Governing Board

CERN Document Server

HR Department

2009-01-01

Reminder Given the current state of the financial markets and the continuing uncertainty as to their future evolution, we begin by reiterating the introductory statement of the last report from the Pension Fund: "The CERN pension scheme is based on the principle of defined benefits, so beneficiaries continue to receive the benefits to which they are entitled in accordance with the Rules of the Pension Fund. This means that pension entitlements under the Rules are not directly affected by the financial crisis and the current economic situation. However, the adjustment of pensions to the cost of living is not automatic and, under the method applied since 2006, must take into account the Fund’s financial position." Meeting of the Pension Fund Governing Board (PFGB) The PFGB held its ninth and tenth meetings on 1st December 2008 and 11 February 2009 respectively. At the ninth meeting, the Governing Board bade farewell to P. Lambert, who had been an expert member since November 2007 and a membe...

Meeting of the Pension Fund Governing Board

CERN Document Server

HR Department

2009-01-01

Reminder Given the current state of the financial markets and the continuing uncertainty as to their future evolution, we begin by reiterating the introductory statement of the last report from the Pension Fund: "The CERN pension scheme is based on the principle of defined benefits, so beneficiaries continue to receive the benefits to which they are entitled in accordance with the Rules of the Pension Fund. This means that pension entitlements under the Rules are not directly affected by the financial crisis and the current economic situation. However, the adjustment of pensions to the cost of living is not automatic and, under the method applied since 2006, must take into account the Fund’s financial position." Meeting of the Pension Fund Governing Board (PFGB) The PFGB held its ninth and tenth meetings on 1st December 2008 and 11 February 2009 respectively. At the ninth meeting, the Governing Board bade farewell to P. Lambert, who had been an expert member since November...

78 FR 35260 - Multistakeholder Meeting To Develop Consumer Data Privacy Code of Conduct Concerning Mobile...

Science.gov (United States)

2013-06-12

...-multistakeholder-process-mobile-application-transparency , for the most current information. Place: The meeting...-transparency , for the most current information. Other Information: The meeting is open to the public and the...-multistakeholder-process-mobile-application-transparency , for the most current information. Dated: June 6, 2013...

Medical devices regulations, standards and practices

CERN Document Server

Ramakrishna, Seeram; Wang, Charlene

2015-01-01

Medical Devices and Regulations: Standards and Practices will shed light on the importance of regulations and standards among all stakeholders, bioengineering designers, biomaterial scientists and researchers to enable development of future medical devices. Based on the authors' practical experience, this book provides a concise, practical guide on key issues and processes in developing new medical devices to meet international regulatory requirements and standards. Provides readers with a global perspective on medical device regulationsConcise and comprehensive information on how to desig

A 3 A sink/source current fast transient response low-dropout G{sub m} driven linear regulator

Energy Technology Data Exchange (ETDEWEB)

Chu Xiuqin; Li Qingwei; Lai Xinquan; Yuan Bing [Institute of Electronic CAD, Xidian University, Xi' an 710071 (China); Li Yanming [School of Electronic and Control Engineering, Chang' an University, Xi' an 710064 (China); Zhao Yongrui, E-mail: liqw309@163.com, E-mail: xqchu@mail.xidian.edu.cn [Key Laboratory of High-Speed Circuit Design and EMC, Ministry of Education, Xidian University, Xi' an 710071 (China)

2011-06-15

A 3 A sink/source G{sub m}-driven CMOS low-dropout regulator (LDO), specially designed for low input voltage and low cost, is presented by utilizing the structure of a current mirror G{sub m} (transconductance) driving technique, which provides high stability as well as a fast load transient response. The proposed LDO was fabricated by a 0.5 {mu}m standard CMOS process, and the die size is as small as 1.0 mm{sup 2}. The proposed LDO dissipates 220 {mu}A of quiescent current in no-load conditions and is able to deliver up to 3 A of load current. The measured results show that the output voltage can be resumed within 2 {mu}s with a less than 1 mV overshoot and undershoot in the output current step from -1.8 to 1.8 A with a 0.1 {mu}s rising and falling time at three 10 {mu}F ceramic capacitors. (semiconductor integrated circuits)

22 CFR 708.6 - Records of closed meetings.

Science.gov (United States)

2010-04-01

... days from the date of receipt of the request for review (excluding Saturdays, Sundays, and legal public... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Records of closed meetings. 708.6 Section 708.6 Foreign Relations OVERSEAS PRIVATE INVESTMENT CORPORATION ADMINISTRATIVE PROVISIONS SUNSHINE REGULATIONS...

77 FR 7125 - Codex Alimentarius Commission: Meeting of the Codex Committee on General Principles

Science.gov (United States)

2012-02-10

... recognizes the importance of providing interested parties the opportunity to obtain background information on... range from recalls to export information to regulations, directives, and notices. Customers can add or... public meeting on March 28, 2012. The objective of the public meeting is to provide information and...

Summary report of consultants meeting on IAEA International Database on Irradiated Nuclear Graphite Properties. 11. meeting of the Technical Steering Committee

International Nuclear Information System (INIS)

Humbert, D.; Wickham, A.J.

2009-05-01

The 11th Meeting of the Technical Steering Committee for the International Database on Irradiated Nuclear Graphite Properties was held on 25-26 March 2009 at the IAEA Headquarters, Vienna, Austria. All discussions, recommendations and actions of this Consultants' Meeting are recorded in this report. The purposes of the meeting were to review the matters and actions identified in the previous meeting, undertake a review of the current status of the database, and make recommendations for action over the next year. This report contains the status of the identified actions as well as a summary of the recommendations on enhancements to the database. (author)

STANDING CONCERTATION COMMITTEE ORDINARY MEETING ON 19 APRIL 1999

CERN Multimedia

1999-01-01

Original: FrenchThe meeting was mainly devoted to examination of the following matters:Administrative circulars- Administrative circular n¡14 (Accidents and illnesses suffered by members of the personnel): The SCC heard a status report on the revision of this circular which, due to the diversity of subjects to be addressed, is a complex process. Consultation with the services concerned has begun and a preliminary draft text codifying the current practice and comprising four separate sections (procedure for determining occupational illnesses and accidents; meanings of the terms incapacity, disability, and unsuitability; death; Joint Advisory Rehabilitation and Disability Board) is being prepared. The Committee endorsed the proposed approach. A more detailed discussion will be held shortly within the SCC Sub-Group on the review of the Staff Rules and Regulations and administrative circulars.- Administrative Circular n¡ 22 (Award of additional periods of membership in the Pension Fund to shift ...

More to NAD+ than meets the eye: A regulator of metabolic pools and gene expression in Arabidopsis.

Science.gov (United States)

Gakière, Bertrand; Fernie, Alisdair R; Pétriacq, Pierre

2018-01-05

Since its discovery more than a century ago, nicotinamide adenine dinucleotide (NAD + ) is recognised as a fascinating cornerstone of cellular metabolism. This ubiquitous energy cofactor plays vital roles in metabolic pathways and regulatory processes, a fact emphasised by the essentiality of a balanced NAD + metabolism for normal plant growth and development. Research on the role of NAD in plants has been predominantly carried out in the model plant Arabidopsis thaliana (Arabidopsis) with emphasis on the redox properties and cellular signalling functions of the metabolite. This review examines the current state of knowledge concerning how NAD can regulate both metabolic pools and gene expression in Arabidopsis. Particular focus is placed on recent studies highlighting the complexity of metabolic regulations involving NAD, more particularly in the mitochondrial compartment, and of signalling roles with respect to interactions with environmental fluctuations most specifically those involving plant immunity. Copyright © 2018 Elsevier Inc. All rights reserved.

75 FR 29988 - Civil Nuclear Trade Advisory Committee Public Meeting

Science.gov (United States)

2010-05-28

..., treaties and regulations, advocacy, and talent and education. Public Participation: The meeting will be... Secretary for Manufacturing, Acting. [FR Doc. 2010-12814 Filed 5-27-10; 8:45 am] BILLING CODE 3510-DR-P ...

Design considerations for high current regulated DC power supplies with reference to 600 kW variable DC power supply

International Nuclear Information System (INIS)

Ushakumari; Garud, A.N.; Nadkarni, S.S.

1980-01-01

High current regulated dc power supplies find increasing applications in industry and research. The power rating of these supplies vary from few killowatts to megawatts. The general requirements of these supplies for various applications and the techniques used to achieve the desired performance are presented. The design and selection of various circuit blocks namely the rectifier transformer, multiphase rectifier arrangement, SCR paralleling and current sensing techniques, are discussed in detail for a 600 killowatt current controlled supply developed in the Bhabha Atomic Research Centre, Bombay, and used for the thermal studies of reactor components. The power supply incorporates paralleled phase controlled thyristors with a closed loop feedback circuitary to achieve a current stability of 0.1% and smooth output variation from 10 to 100%. (auth.)

7 CFR 318.13-17 - Regulated articles from Guam.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Regulated articles from Guam. 318.13-17 Section 318.13... Articles From Hawaii and the Territories § 318.13-17 Regulated articles from Guam. (a)(1) Regulated articles, other than soil, may be moved from Guam into or through any other State only if they meet the...

6. Meeting of European Radioisotope Producers

International Nuclear Information System (INIS)

1979-01-01

This paper contains the abstracts of the meeting lectures. Most of them are reviews on the current state and tendencies of isotope production in different countries, only some few concern production processes and quality control

75 FR 27353 - Navigation Safety Advisory Council; Meeting

Science.gov (United States)

2010-05-14

... meet at the Courtyard by Marriott Washington Capitol Hill/Navy Yard Hotel, Admiral I and II Conference... online docket, USCG-2010-0387, at http://www.regulations.gov . FOR FURTHER INFORMATION CONTACT: Mr. Mike... Installations (OREI) NVIC 02-07 review. (3) Designation of ``narrow channels'' for Inland Navigation Rule 9...

Serotonin Regulates the Firing of Principal Cells of the Subiculum by Inhibiting a T-type Ca(2+) Current

DEFF Research Database (Denmark)

Petersen, Anders V; Jensen, Camilla S; Crépel, Valérie

2017-01-01

The subiculum is the main output of the hippocampal formation. A high proportion of its principal neurons fire action potentials in bursts triggered by the activation of low threshold calcium currents. This firing pattern promotes synaptic release and regulates spike-timing-dependent plasticity. ...... of epileptiform discharges induced in in vitro models for temporal lobe epilepsy (TLE)....

Internal auditors meet at CERN

CERN Multimedia

2008-01-01

What does CERN have in common with INTERPOL? The answer: the challenge of managing a complex international organisation operating outside national regulations. Participants of the internal audit conference had the opportunity to visit ATLAS.On 17th &18th April CERN hosted a meeting for the Internal Audit Heads of some of the most famous international organisations in the world. Sixteen organisations were represented at the conference, including the European Commission, INTERPOL, the European Central Bank, the OECD, the European Space Agency (ESA), NATO and the European Organisation for Astronomical Research in the Southern Hemisphere (ESO). The objective of this annual meeting is to share best practices and benchmark performance in the fields of auditing, organizational governance, risk management and internal controls. International organisations, due to their specific legal status and the absence of applicable national legisl...

78 FR 14153 - Advisory Council on Transportation Statistics; Meeting

Science.gov (United States)

2013-03-04

...., Washington, DC. The Bureau of Transportation Statistics (BTS) will reschedule the meeting for a future date. Currently, BTS is developing a draft agenda. The following is a summary of the draft meeting agenda: (1... performance measures; (4) Update on BTS data programs and future plans (5) Council Members review and...

Cell cycle-dependent regulation of kainate-induced inward currents in microglia

International Nuclear Information System (INIS)

Yamada, Jun; Sawada, Makoto; Nakanishi, Hiroshi

2006-01-01

Microglia are reported to have α-amino-hydroxy-5-methyl-isoxazole-4-propionate/kainate (KA) types. However, only small population of primary cultured rat microglia (approximately 20%) responded to KA. In the present study, we have attempted to elucidate the regulatory mechanism of responsiveness to KA in GMIR1 rat microglial cell line. When the GMIR1 cells were plated at a low density in the presence of granulocyte macrophage colony-stimulating factor, the proliferation rate increased and reached the peak after 2 days in culture and then gradually decreased because of density-dependent inhibition. At cell proliferation stage, approximately 80% of the GMIR1 cells exhibited glutamate (Glu)- and KA-induced inward currents at cell proliferation stage, whereas only 22.5% of the cells showed responsiveness to Glu and KA at cell quiescent stage. Furthermore, the mean amplitudes of inward currents induced by Glu and KA at cell proliferation stage (13.8 ± 3.0 and 8.4 ± 0.6 pA) were significantly larger than those obtained at cell quiescent stage (4.7 ± 0.8 and 6.2 ± 1.2 pA). In the GMIR1 cells, KA-induced inward currents were markedly inhibited by (RS)-3-(2-carboxybenzyl) willardiine (UBP296), a selective antagonist for KA receptors. The KA-responsive cells also responded to (RS)-2-amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl) propanoic acid (ATPA), a selective agonist for GluR5, in both GMIR1 cells and primary cultured rat microglia. Furthermore, mRNA levels of the KA receptor subunits, GluR5 and GluR6, at the cell proliferation stage were significantly higher than those at the cell quiescent stage. Furthermore, the immunoreactivity for GluR6/7 was found to increase in activated microglia in the post-ischemic hippocampus. These results strongly suggest that microglia have functional KA receptors mainly consisting of GluR5 and GluR6, and the expression levels of these subunits are closely regulated by the cell cycle mechanism

UK: the current state of regulation of complementary and alternative medicine.

Science.gov (United States)

Walker, L A; Budd, S

2002-03-01

There is no legislation that restricts the practice of CAM in the UK apart from the practice of chiropractic and osteopathy and limits on advertising the treatments of certain conditions such as cancer and tuberculosis. The UK government has increasingly recognised the need for comprehensive regulation of CAM, though it abandoned its original plan for a single overarching regulatory body. Initiatives to examine and hasten the process of regulation have included setting up a central, well-recognised charitable body to facilitate progress for individual professions, and an authoritative survey of the existing professional organisations. One pathway open to individual professions is statutory self-regulation, which requires a single governing body, a systematic corpus of knowledge, recognised training courses and demonstrated efficacy. The other pathway is voluntary self-regulation. Chiropractic and osteopathy have adopted statutory self-regulation, though this has proved expensive for individual members of these professions. A recent House of Lords report on CAM has recommended that the herbal medicine and acupuncture professions should also develop a system of statutory regulation. Other professions, such as aromatherapy, are in the process of establishing single professional bodies as a first step towards self-regulation. Among the issues that remain to be resolved is the relationship between the CAM professions and statutory registered practitioners who also practise CAM.

Measurement technology of RF interference current in high current system

Science.gov (United States)

Zhao, Zhihua; Li, Jianxuan; Zhang, Xiangming; Zhang, Lei

2018-06-01

Current probe is a detection method commonly used in electromagnetic compatibility. With the development of power electronics technology, the power level of power conversion devices is constantly increasing, and the power current of the electric energy conversion device in the electromagnetic launch system can reach 10kA. Current probe conventionally used in EMC (electromagnetic compatibility) detection cannot meet the test requirements on high current system due to the magnetic saturation problem. The conventional high current sensor is also not suitable for the RF (Radio Frequency) interference current measurement in high current power device due to the high noise level in the output of active amplifier. In this paper, a passive flexible current probe based on Rogowski coil and matching resistance is proposed that can withstand high current and has low noise level, to solve the measurement problems of interference current in high current power converter. And both differential mode and common mode current detection can be easily carried out with the proposed probe because of the probe's flexible structure.

Current insights into hormonal regulation of microspore embryogenesis

Directory of Open Access Journals (Sweden)

Iwona eŻur

2015-06-01

Full Text Available Plant growth regulator (PGR crosstalk and interaction with the plant’s genotype and environmental factors play a crucial role in microspore embryogenesis (ME, controlling microspore-derived embryo differentiation and development as well as haploid/doubled haploid plant regeneration. The complexity of the PGR network which could exist at the level of biosynthesis, distribution, gene expression or signaling pathways, renders the creation of an integrated model of ME-control crosstalk impossible at present. However, the analysis of the published data together with the results received recently with the use of modern analytical techniques brings new insights into hormonal regulation of this process. This review presents a short historical overview of the most important milestones in the recognition of hormonal requirements for effective ME in the most important crop plant species and complements it with new concepts that evolved over the last decade of ME studies.

77 FR 37446 - Advisory Committee on the Medical Uses of Isotopes: Meeting Notice

Science.gov (United States)

2012-06-21

... convene a regular meeting of the ACMUI on September 20-21, 2012. A sample of agenda items to be discussed...; and (6) update on domestic production of molybdenum-99. The regular meeting agenda is subject to change. The current agendas for both meetings and any updates will be available prior to the meetings at...

Federal Aviation Regulations - National Aviation Regulations of Russia

Science.gov (United States)

Chernykh, O.; Bakiiev, M.

2018-03-01

Chinese Aerospace Engineering is currently developing cooperation with Russia on a wide-body airplane project that has directed the work towards better understanding of Russian airworthiness management system. The paper introduces national Aviation regulations of Russia, presents a comparison of them with worldwide recognized regulations, and highlights typical differences. They have been found to be: two general types of regulations used in Russia (Aviation Regulations and Federal Aviation Regulations), non-unified structure of regulations on Aircraft Operation management, various separate agencies responsible for regulation issuance instead of one national aviation authority, typical confusions in references. The paper also gives a list of effective Russian Regulations of both types.

IAEA technical meeting: Assess and co-ordinate modelling needs and data providers. Summary report

International Nuclear Information System (INIS)

Clark, R.E.H.

2004-05-01

This report briefly describes the proceedings, conclusions and recommendations of the Technical Meeting to 'Assess and Co-ordinate Modelling Needs and Data Providers', held on 4-5 December 2003. Eight international experts on atomic and molecular data related to fusion energy research activities participated in the meeting. Each participant reviewed the current status of their own speciality and current lines of research as well as anticipated needs in new data for nuclear fusion energy research. Current CRPs on related topics were reviewed. In light of current research activities and anticipated data needs for fusion, a detailed set of tasks appropriate for a new CRP was developed. This meeting completely fulfilled the specified goals. (author)

International Cooperation in the Area of Nuclear Safety Regulation: Current Status and Way Forward

Energy Technology Data Exchange (ETDEWEB)

Yoo, J. W.; Byeon, M. J.; Lee, J. M.; Lim, J. H. [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

2016-10-15

Global effort and initiatives undertaken after the Fukushima Daiichi accident was the adoption of the Vienna Declaration on Nuclear Safety in February 2015. The Contracting Parties to the Convention on Nuclear Safety (CNS) collaboratively prepared the documentation of the Declaration and unanimously adopted it with the idea to prevent accidents with radiological consequences and to mitigate such consequences should they occur. The OECD/NEA has been working closely with its member and partner countries to identify lessons learnt and follow-up actions at the national and international levels so as to maintain and enhance the level of safety at nuclear facilities following the Fukushima Daiichi nuclear power plant accident. In 2013, the NEA published a report entitled The Fukushima Daiichi Nuclear Power Plant Accident: OECD/NEA Nuclear Safety Response and Lessons Learnt detailing the key immediate responses of the NEA and its member countries. Subsequent to the publish of the report and based on the lessons presented, NEA published a new report entitled Five Years after the Fukushima Daiichi Accident: Nuclear Safety Improvements and Lessons Learnt, focusing on what has been done by the Agency and its member countries to improve safety since the accident in 2011. cooperation based on the needs of technical area would further enhance effectiveness of cooperative activities and would enable to foresee future regulatory needs which can be considered when establishing a strategy. Since the establishment of NSSC in 2011, NSSC has played a major role in concluding agreements with regulatory bodies of other countries. Despite of the change, KINS, yet, is able to pursue technical-specified cooperation as a TSO under the umbrella of agreements between governments or regulatory bodies. establishment of expert pool and systematic mid- and long-term capacity building framework of relevant experts would enhance continuity and expertise. Currently, most of the participants or

77 FR 22286 - Western Pacific Fishery Management Council; Public Meeting

Science.gov (United States)

2012-04-13

... Pacific Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS.... SUMMARY: The Western Pacific Fishery Management Council (Council) will hold a meeting of its Pelagics Plan... pelagics annual report module changes 4. American Samoa annual report module changes 5. Summary of current...

Dynamic, nonlinear feedback regulation of slow pacemaking by A-type potassium current in ventral tegmental area neurons.

Science.gov (United States)

Khaliq, Zayd M; Bean, Bruce P

2008-10-22

We analyzed ionic currents that regulate pacemaking in dopaminergic neurons of the mouse ventral tegmental area by comparing voltage trajectories during spontaneous firing with ramp-evoked currents in voltage clamp. Most recordings were made in brain slice, with key experiments repeated using acutely dissociated neurons, which gave identical results. During spontaneous firing, net ionic current flowing between spikes was calculated from the time derivative of voltage multiplied by cell capacitance, signal-averaged over many firing cycles to enhance resolution. Net inward interspike current had a distinctive nonmonotonic shape, reaching a minimum (generally current that peaked near -55 mV. This current was undetectable with 5 mV/s ramps and increased steeply with depolarization rate over the range (10-50 mV/s) typical of natural pacemaking. Ramp-evoked subthreshold current was resistant to alpha-dendrotoxin, paxilline, apamin, and tetraethylammonium but sensitive to 4-aminopyridine and 0.5 mM Ba2+, consistent with A-type potassium current (I(A)). Same-cell comparison of currents elicited by various ramp speeds with natural spontaneous depolarization showed how the steep dependence of I(A) on depolarization rate results in small net inward currents during pacemaking. These results reveal a mechanism in which subthreshold I(A) is near zero at steady state, but is engaged at depolarization rates >10 mV/s to act as a powerful, supralinear feedback element. This feedback mechanism explains how net ionic current can be constrained to <1-2 pA but reliably inward, thus enabling slow, regular firing.

Current puzzles in nuclear physics

International Nuclear Information System (INIS)

1985-01-01

A meeting on ''Current puzzles in nuclear physics'' was held at Research Center for Nuclear Physics, Osaka University, on June 27 - 28, 1984. The meeting put emphasis on several puzzles which have not been solved for a long time in nuclear physics, and also on the puzzles. This collective report is composed of following eleven papers presented at the meeting. Almost all the papers are witten in English : (1) M1, GT excitations and configuration mixing (in Japanese). (2) Hadronic excitation of pionic states. (3) Microscopic analyses of 28 Si(α,α') 28 Si scattering and single particle strength in A = 29 nuclei. (4) Few-body physics and its incentives to nuclear physics. (5) Is it necessary to introduce three body interactions ? (in Japanese). (6) Puzzles in the neutron-deuteron elastic scattering. (7) Puzzles in NN, NΔ, πN and Nanti N interactions. (8) Problems in Hadron-Nucleus interaction. (9) Unified approach to the meson- and quark- theory of nuclear forces and currents. (10) Pion photoproduction in two Chiral bag models. (11) The dynamic bag model : The electromagnetic properties of nucleon. (Aoki, K.)

Meeting the regulatory information needs of users of radioactive materials

International Nuclear Information System (INIS)

MacDurmon, G.W.

1996-01-01

The use of radioactive materials is one of the most regulated areas of research. Researchers face ever increasing regulatory requirements and issues involving the disposal of radioactive material, while meeting the demands of higher productivity. Radiation safety programs must maximize regulatory compliance, minimize barriers, provide services and solutions, and effectively communicate with users of radioactive materials. This talk will discuss methods by which a radiation safety program can meet the needs of both the research staff and regulatory compliance staff

Meeting the regulatory information needs of users of radioactive materials

Energy Technology Data Exchange (ETDEWEB)

MacDurmon, G.W. [American Cyanamid Company, Princeton, NJ (United States)

1996-10-01

The use of radioactive materials is one of the most regulated areas of research. Researchers face ever increasing regulatory requirements and issues involving the disposal of radioactive material, while meeting the demands of higher productivity. Radiation safety programs must maximize regulatory compliance, minimize barriers, provide services and solutions, and effectively communicate with users of radioactive materials. This talk will discuss methods by which a radiation safety program can meet the needs of both the research staff and regulatory compliance staff.

Regulation on Radiation Safety of Guatemala

International Nuclear Information System (INIS)

2001-03-01

This regulation includes all the requirements administrative, radiation protection, that licensees must meet in order to obtain authorization from the competent authority to apply and use radiation sources, equipment emiting ionizing radiation in different practices authorized

77 FR 16898 - Genomic Medicine Program Advisory Committee, Notice of Meeting

Science.gov (United States)

2012-03-22

... protecting the privacy of Veterans. The meeting focus will be on policies, regulations, and implications for... Secretary of Veterans Affairs on using genetic information to optimize medical care of Veterans, and to...

Former Soviet Regulations for seismic design of NPPs and comparison with current international practice

International Nuclear Information System (INIS)

Kostarev, V.; Schukin, A.; Berkovski, A.

1997-01-01

This paper presents a summary of current earthquake design criteria used in former Soviet Regulations for equipment and piping systems of nuclear power plants in light of those used in United States and Japan. The detailed comparative seismic analysis of PWR (WWER) Primary Coolant Loop System (PCLS) according to Former Soviet (Russian) PNAE Code and ASME BPV Code with some comments regarding to Japan Code JEAG - 4601 was undertaken for better understanding of the differences and coincidences of seismic design criteria and requirements. The selection of these three guides for the study has very simple explanation: according to ASME BVPC, JEAG and PNAE the huge majority of existing NPPs has been designed. (J.P.N.)

Former Soviet Regulations for seismic design of NPPs and comparison with current international practice

Energy Technology Data Exchange (ETDEWEB)

Kostarev, V; Schukin, A; Berkovski, A [CKTI-Vibroseism Co. Ltd. (Cape Verde)

1997-03-01

This paper presents a summary of current earthquake design criteria used in former Soviet Regulations for equipment and piping systems of nuclear power plants in light of those used in United States and Japan. The detailed comparative seismic analysis of PWR (WWER) Primary Coolant Loop System (PCLS) according to Former Soviet (Russian) PNAE Code and ASME BPV Code with some comments regarding to Japan Code JEAG - 4601 was undertaken for better understanding of the differences and coincidences of seismic design criteria and requirements. The selection of these three guides for the study has very simple explanation: according to ASME BVPC, JEAG and PNAE the huge majority of existing NPPs has been designed. (J.P.N.)

CSNI specialist meeting on simulators and plant analyzers

International Nuclear Information System (INIS)

Miettinen, J.; Holmstroem, H.

1994-01-01

The Specialist Meeting on Simulators and Plant Analyzers, held in June 9-12, 1992, in Lappeenranta, Finland, was sponsored by the Committee on the Safety on Nuclear Installations (CSNI) of the OECD Nuclear Energy Agency (NEA). It was organized in collaboration with the Technical Research Centre of Finland (VTT) and the Lappeenranta Technical University of Technology (LTKK). All the presented papers were invited and devided into four sessions. In the first session the objectives, requirements and consepts of simulators were discussed against present standards and guidelines. The second session focused on the capabilities of current analytical models. The third session focused on the experiences gained so far from the applications. The final fourth session concentrated on simulators, which are currently under development, and future plans with regard to both development and utilization. At the end of the meeting topics of the meeting were discussed at the panel discussion. Summaries of the sessions and shortened version of the panel discussion are included into the proceeding. (orig.)

Current and proposed revisions, changes, and modifications to American codes and standards to address packaging, handling, and transportation of radioactive materials and how they relate to comparable international regulations

International Nuclear Information System (INIS)

Borter, W.H.; Froehlich, C.H.

2004-01-01

This paper addresses current and proposed revisions, additions, and modifications to American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code (BPVC) (i.e., ''ASMEthe Code'') Section III, Division 3 and American National Standards Institute (ANSI)/ASME N14.6. It provides insight into the ongoing processes of the associated committees and highlights important revisions, changes, and modifications to this Code and Standard. The ASME Code has developed and issued Division 3 to address items associated with the transportation and storage of radioactive materials. It currently only addresses ''General Requirements'' in Subsections WA and ''Class TP (Type B) Containments'' (Transportation Packages) in Subsection WB, but is in the process of adding a new Subsection WC to address ''Class SC'' (Storage Containments). ANSI/ASME Standard N14.6 which interacts with components constructed to Division 3 by addressinges special lifting devices for radioactive material shipping containers. This Standard is in the process of a complete re-write. This Code and Standard can be classified as ''dynamic'' in that their committees meet at least four times a year to evaluate proposed modifications and additions that reflect current safety practices in the nuclear industry. These evaluations include the possible addition of new materials, fabrication processes, examination methods, and testing requirements. An overview of this ongoing process is presented in this paper along with highlights of the more important proposed revisions, changes, and modifications and how they relate to United States (US) and international regulations and guidance like International Atomic Energy Agency (IAEA) Requirement No. TS-R-1

29 CFR 1612.4 - Exemptions to open meeting policy.

Science.gov (United States)

2010-07-01

... 29 Labor 4 2010-07-01 2010-07-01 false Exemptions to open meeting policy. 1612.4 Section 1612.4 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION GOVERNMENT IN...) disclose investigative techniques and procedures, or (6) endanger the life of physical safety of law...

22 CFR 1500.9 - Transcripts, recording of closed meetings.

Science.gov (United States)

2010-04-01

..., closed to the public. (b) The Foundation, after review by the General Counsel, shall make promptly... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Transcripts, recording of closed meetings. 1500.9 Section 1500.9 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION SUNSHINE REGULATIONS § 1500.9...

75 FR 61119 - Notice of Public Meeting of the Committee on Regulation

Science.gov (United States)

2010-10-04

... on the report to be considered at the meeting, to be submitted in writing no later than October 14... p.m. to 5 p.m. to consider a report examining agency procedures for determining whether to preempt... York University School of Law, Catherine M. Sharkey, to research and prepare a report regarding the...

39 CFR 6.1 - Regular meetings, annual meeting.

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Regular meetings, annual meeting. 6.1 Section 6.1 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE MEETINGS (ARTICLE VI) § 6.1 Regular meetings, annual meeting. The Board shall meet regularly on a schedule...

77 FR 72831 - Meeting of the Ocean Research Advisory Panel

Science.gov (United States)

2012-12-06

... commentary. ADDRESSES: The meeting will be held at the Consortium for Ocean Leadership, 1201 New York Avenue... Committee Act (5 U.S.C. App. 2). The meeting will include discussions on ocean research, resource management, and other current issues in the ocean science and management communities. Dated: November 29, 2012. L...

Summary report of consultants' meeting on IAEA international database on irradiated nuclear graphite properties

International Nuclear Information System (INIS)

Humbert, D.; Wickham, A.J.

2007-06-01

The '9th Meeting of the Technical Steering Committee for the International Database on Irradiated Nuclear Graphite Properties' was held on 26-27 March 2007 at the IAEA Headquarters, Vienna, Austria. All discussions, recommendations and actions of this Consultants' Meeting are recorded in this report. The purposes of the meeting were to review the matters and actions identified in the previous meeting, undertake a review of the current status of the database and make recommendations for actions for the next year. This report contains the current status of the identified actions as well as a summary of the recommendations on enhancements to the database. (author)

Royal Society Scientific Meeting: Extracellular vesicles in the tumour microenvironment.

Science.gov (United States)

Pink, Ryan Charles; Elmusrati, Areeg A; Lambert, Daniel; Carter, David Raul Francisco

2018-01-05

Cancer cells do not grow as an isolated homogeneous mass; tumours are, in fact, complex and heterogeneous collections of cancer and surrounding stromal cells, collectively termed the tumour microenvironment. The interaction between cancer cells and stromal cells in the tumour microenvironment has emerged as a key concept in the regulation of cancer progression. Understanding the intercellular dialogue in the tumour microenvironment is therefore an important goal. One aspect of this dialogue that has not been appreciated until recently is the role of extracellular vesicles (EVs). EVs are small vesicles released by cells under both normal and pathological conditions; they can transfer biological molecules between cells leading to changes in phenotype. EVs have emerged as important regulators of biological processes and can be dysregulated in diseases such as cancer; rapidly growing interest in their biology and therapeutic potential led to the Royal Society hosting a Scientific Meeting to explore the roles of EVs in the tumour microenvironment. This cross-disciplinary meeting explored examples of how aberrant crosstalk between tumour and stromal cells can promote cancer progression, and how such signalling can be targeted for diagnostic, prognostic and therapeutic benefit. In this review, and the special edition of Philosophical Transactions of the Royal Society B that follows, we will provide an overview of the content and outcomes of this exciting meeting.This article is part of the discussion meeting issue 'Extracellular vesicles and the tumour microenvironment'. © 2017 The Author(s).

Summary of the 2016 Alcohol and Immunology Research Interest Group (AIRIG) meeting.

Science.gov (United States)

Boule, Lisbeth A; Ju, Cynthia; Agudelo, Marisela; Parira, Tiyash; Cannon, Abigail; Davis, Booker; Eby, Jonathan; Cresci, Gail; Samuelson, Derrick R; Shukla, Pradeep; Alrefai, Waddah A; Sureshchandra, Suhas; Pandey, Subhash C; Schnabl, Bernd; Curtis, Brenda J; Wyatt, Todd A; Choudhry, Mashkoor A; Kovacs, Elizabeth J

2018-02-01

On November 18, 2016 the 21st annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held at the Center for Translational Research and Education at Loyola University Chicago's Health Sciences Campus in Maywood, IL. The 2016 meeting focused broadly on alcohol and inflammation, epigenetics, and the microbiome. The four plenary sessions of the meeting were Alcohol, Inflammation, and Immunity; Alcohol and Epigenetics; Alcohol, Transcriptional Regulation, and Epigenetics; and Alcohol, Intestinal Mucosa, and the Gut Microbiome. Presentations in all sessions of the meeting explored putative underlying causes for chronic diseases and mortality associated with alcohol consumption, shedding light on future work and potential therapeutic targets to alleviate the negative effects of alcohol misuse. Copyright © 2017 Elsevier Inc. All rights reserved.

How Do Enzymes 'Meet' Nanoparticles and Nanomaterials?

Science.gov (United States)

Chen, Ming; Zeng, Guangming; Xu, Piao; Lai, Cui; Tang, Lin

2017-11-01

Enzymes are fundamental biological catalysts responsible for biological regulation and metabolism. The opportunity for enzymes to 'meet' nanoparticles and nanomaterials is rapidly increasing due to growing demands for applications in nanomaterial design, environmental monitoring, biochemical engineering, and biomedicine. Therefore, understanding the nature of nanomaterial-enzyme interactions is becoming important. Since 2014, enzymes have been used to modify, degrade, or make nanoparticles/nanomaterials, while numerous nanoparticles/nanomaterials have been used as materials for enzymatic immobilization and biosensors and as enzyme mimicry. Among the various nanoparticles and nanomaterials, metal nanoparticles and carbon nanomaterials have received extensive attention due to their fascinating properties. This review provides an overview about how enzymes meet nanoparticles and nanomaterials. Copyright © 2017 Elsevier Ltd. All rights reserved.

Linking pre-meeting communication to meeting effectiveness

NARCIS (Netherlands)

Allen, J.A.; Lehmann-Willenbrock, N.K.; Landowski, N.

2014-01-01

Purpose – The purpose of this paper is to investigate the importance of communication that occurs just before workplace meetings (i.e. pre-meeting talk). The paper explores how four specific types of pre-meeting talk (small talk, work talk, meeting preparatory talk, and shop talk) impact

Encountering Challenges with the EU Regulation on Advance Therapy Medical Products.

Science.gov (United States)

Mansnérus, Juli

2015-12-01

This article aims at analysing how well the Advanced Therapy Medical Product Regulation (EC) No. 1394/2007 (ATMP Regulation) meets the needs of small and medium-sized enterprises (SMES), academia and public tissue establishments developing advanced therapy medical products (ATMPS). Benefits and shortcomings of the ATMP Regulation are identified, and possible amendments are proposed to accelerate the translation of research into advanced therapies and to facilitate the commercialisation of ATMPS whilst ensuring safety. It was set up as a lex specialis to ensure the free movement of ATMPS within the EU in order to facilitate their access to the internal market and to foster the competitiveness of European pharmaceutical companies, while guaranteeing the highest level protection of public health. Since the adoption of the ATMP Regulation in late 2008, only 5 ATMPS have been granted marketing authorisations thus far. Hence, there is a need to analyse whether the ATMP Regulation meets its objectives.

Regulations and classification advice: transport safety

International Nuclear Information System (INIS)

Davies, M.; Owen, K.

1990-01-01

The packaging of radioactive material for transport must conform with the regulations of the International Atomic Energy Agency (IAEA). These regulations are extensive and complex and require specialist interpretation. Packaging must be designed to contain the material, to limit radiation to safe levels, and to maintain the material in a safe state under both normal and accident conditions. British Nuclear Fuels Ltd. (BNFL) developed the TRANAID expert system to provide automated expert advice on the subject. It is used at BNFL and by other users internationally. The system was produced to meet an internal BNFL emphasis on accurate consistent and reliable interpretation of the complex IAEA regulations; and to provide a commercial product which would meet an external need. TRANAID provides reliable and consistent advice on safe transport procedures which reduce the workload on scarce skilled personnel, and allows them to concentrate on their primary task of packaging design. TRANAID also avoids overclassifying radioactive shipments, which would lead to the use of more expensive packaging than strictly is required. The IAEA regulations are applied internationally, and so there is a large potential worldwide market. The indications from the initial response are that future sales and use are expected to more than cover the investment. Other non-quantifiable benefits include the provision of consistent advice within a uniform approach, the safe-guarding of knowledge of the IAEA regulations, training and improvement in the expertise of users, improved management control, and enhancement of the professional image of BNFL. (author)

SOR/89-426, Transport Packaging of Radioactive Materials Regulations, amendment

International Nuclear Information System (INIS)

1989-01-01

These Regulations of 24 August 1989 amend the Transport Packaging of Radioactive Materials Regulations by clarifying the text and specifying certain requirements. In particular certain definitions have been replaced, namely those of ''Fissile Class III package'' and ''Special form radioactive material''. Also, this latter material may not be carried without a certificate attesting that it meets the requirements of the Regulations. (NEA)

Meetings and meeting modeling in smart surroundings

NARCIS (Netherlands)

op den Akker, Hendrikus J.A.; Heylen, Dirk K.J.; Nijholt, Antinus; Nishida, T.

2004-01-01

In this paper we survey our research on smart meeting rooms and its relevance for augmented reality meeting support and virtual reality generation of meetings in real-time or off-line. Intelligent real-time and off-line generation requires understanding of what is going on during a meeting. The

Nursing and midwifery regulation and HIV scale-up: establishing a baseline in East, Central and Southern Africa.

Science.gov (United States)

McCarthy, Carey F; Voss, Joachim; Verani, Andre R; Vidot, Peggy; Salmon, Marla E; Riley, Patricia L

2013-03-25

Shifting HIV treatment tasks from physicians to nurses and midwives is essential to scaling-up HIV services in sub-Saharan Africa. Updating nursing and midwifery regulations to include task shifting and pre-service education reform can help facilitate reaching new HIV targets. Donor-supported initiatives to update nursing and midwifery regulations are increasing. However, there are gaps in our knowledge of current practice and education regulations and a lack of information to target and implement regulation strengthening efforts. We conducted a survey of national nursing and midwifery councils to describe current nursing and midwifery regulations in 13 African countries. A 30-item survey was administered to a convenience sample of 13 national nursing and midwifery regulatory body leaders in attendance at the PEPFAR-supported African Health Profession Regulatory Collaborative meeting in Nairobi, Kenya on 28 February, 2011. The survey contained questions on task shifting and regulations such as registration, licensure, scope of practice, pre-service education accreditation, continuing professional development and use of international guidelines. Survey data were analyzed to present country-level, comparative and regional findings. Task shifting to nurses and midwives was reported in 11 of the 13 countries. Eight countries updated their scope of practice within the last five years; only one reported their regulations to reflect task shifting. Countries vary with regard to licensure, pre-service accreditation and continuing professional development regulations in place. There was no consistency in terms of what standards were used to design national practice and education regulations. Many opportunities exist to assist countries to modernise regulations to incorporate important advancements from task shifting and pre-service reform. Appropriate, revised regulations can help sustain successful health workforce strategies and contribute to further scale-up HIV services

IAEA International Database on Irradiated Nuclear Graphite Properties. 7th meeting of the Technical Steering Committee

International Nuclear Information System (INIS)

Humbert, D.; Wickham, A.J.

2005-06-01

This report summarizes the Consultant Meeting '7th Meeting of the Technical Steering Committee for the International Database on Irradiated Nuclear Graphite Properties' held on 16-17 March 2005 at the IAEA Headquarters, Vienna, Austria. The purposes of the meeting were to review the matters and actions identified in the previous meeting, undertake a review of the current status of the database and to make recommendations for actions for the next year. The purposes of the meeting were fully met. This report contains the current status of the identified actions as well as a summary of the recommendations on enhancements to the database. (author)

IAEA International Database on Irradiated Nuclear Graphite Properties. 6th meeting of the Technical Steering Committee

International Nuclear Information System (INIS)

Humbert, D.; Wickham, A.J.

2004-12-01

This report summarizes the Consultant Meeting 6th Meeting of the Technical Steering Committee for the International Database on Irradiated Nuclear Graphite Properties' held on 16-17 September 2004 at Plas Tan-Y-Bwlch, Maentwrog, Gwynedd, UK. The purposes of the meeting were to review the matters and actions identified in the previous meeting, undertake a review of the current status of the database and to make recommendations for actions for the next year. The purposes of the meeting were fully met. This report contains the current status of the identified actions as well as a summary of the recommendations on enhancements to the database. (author)

Board meeting frequency and corporate social responsibility (CSR reporting: Evidence from Malaysia

Directory of Open Access Journals (Sweden)

Nurulyasmin Binti Ju Ahmad

2017-05-01

Full Text Available This study aims at determining the effectiveness of board meeting frequency on Corporate Social Responsibility (CSR reporting by public listed companies on the Main Market of Bursa Malaysia. A CSR reporting index consisting of 51 items was developed based on six themes: General, Community, Environment, Human Resource, Marketplace and Other. A content analysis was used to determine the extent of CSR reporting. An Ordinary Least Square (OLS regression was employed in determining the association between board meeting frequency and CSR reporting. The finding of the study is that advising tendency (frequency of board meetings is not associated with CSR reporting. Overall this study strengthens the idea that advising tendency of the board is essential to companies in order to safeguard all stakeholders’ interests. Accordingly, regulators and policymakers should be more stringent in monitoring company’s conformance towards regulations. This study provides a new avenue of knowledge and contributes to the literature on the practices of the board of directors and corporate social responsibility reporting in the context of a semi-developed country

Current regulator for the stabilization of an electrostatic Van de Graaff generator; Regulateur de courant pour stabilisation d'un generateur electrostatique Van de Graaff

Energy Technology Data Exchange (ETDEWEB)

Gabet, A; Taieb, J [Commissariat a l' Energie Atomique, Saclay(France). Centre d' Etudes Nucleaires

1953-07-01

In a previous report (CEA report number 46) we described a current regulator destined to enslave the current of charge of the strap of a model of Van de Graaff. We will now describe the regulator destined to the 5 MeV Van de Graaff built in the Nuclear center of Saclay. (author) [French] Dans un precedent rapport (rapport C.E.A. numero 46) nous avons decrit un regulateur de courant destine a asservir le courant de charge de la courroie d'une maquette de Van de Graaff. Nous decrirons maintenant le regulateur destine au Van de Graaff de 5 MeV construit au Centre d'Etudes Nucleaires de Saclay. (auteur)

Meetings and Meeting Modeling in Smart Environments

NARCIS (Netherlands)

Nijholt, Antinus; op den Akker, Hendrikus J.A.; Heylen, Dirk K.J.

In this paper we survey our research on smart meeting rooms and its relevance for augmented reality meeting support and virtual reality generation of meetings in real time or off-line. The research reported here forms part of the European 5th and 6th framework programme projects multi-modal meeting

Towards trust in regulation. Moving to a public value regulation

Energy Technology Data Exchange (ETDEWEB)

Mitchell, Catherine; Woodman, Bridget [Energy Policy Group, University of Exeter Cornwall Campus, Treliever Road, Penryn, TR10 9EZ (United Kingdom)

2010-06-15

The UK Government has committed itself to reducing its carbon dioxide emissions. The challenge of successfully achieving a transition to a sustainable energy system, in the context of the UK's largely privately owned energy industry, rests on the ability of policy makers to encourage and enable the necessary changes or innovation at all levels of the energy system. This paper argues that the UK's current, dominant political paradigm or framework (the regulatory state paradigm (RSP)) and within it, the role of the economic regulator, Ofgem acts as a fundamental block to this challenge. The current economic regulatory system is based on trust in the market, or on predicted (albeit theoretical) known outcomes. To expand our regulatory system to one which can deliver a sustainable energy system requires innovation in a certain direction (as opposed to any innovation). That is the antithesis of the current process of regulation. Trust is required that Ofgem, the economic regulator, will develop rules and incentives which deliver an agreed sustainable energy goal, which is 'trusted' to be the 'right' goal. This requires Ofgem moving away from ex-ante regulation to a type of regulation where all costs, benefits and outcomes cannot be known beforehand and where they cannot necessarily be quantifiable. This has, very provisionally, been called Public Value Regulation (PVR). (author)

Towards trust in regulation-moving to a public value regulation

Energy Technology Data Exchange (ETDEWEB)

Mitchell, Catherine, E-mail: catherine.mitchell@exeter.ac.u [Energy Policy Group, University of Exeter Cornwall Campus, Treliever Road, Penryn, TR10 9EZ (United Kingdom); Woodman, Bridget [Energy Policy Group, University of Exeter Cornwall Campus, Treliever Road, Penryn, TR10 9EZ (United Kingdom)

2010-06-15

The UK Government has committed itself to reducing its carbon dioxide emissions. The challenge of successfully achieving a transition to a sustainable energy system, in the context of the UK's largely privately owned energy industry, rests on the ability of policy makers to encourage and enable the necessary changes or innovation at all levels of the energy system. This paper argues that the UK's current, dominant political paradigm or framework (the regulatory state paradigm (RSP)) and within it, the role of the economic regulator, Ofgem acts as a fundamental block to this challenge. The current economic regulatory system is based on trust in the market, or on predicted (albeit theoretical) known outcomes. To expand our regulatory system to one which can deliver a sustainable energy system requires innovation in a certain direction (as opposed to any innovation). That is the antithesis of the current process of regulation. Trust is required that Ofgem, the economic regulator, will develop rules and incentives which deliver an agreed sustainable energy goal, which is 'trusted' to be the 'right' goal. This requires Ofgem moving away from ex-ante regulation to a type of regulation where all costs, benefits and outcomes cannot be known beforehand and where they cannot necessarily be quantifiable. This has, very provisionally, been called Public Value Regulation (PVR).

Towards trust in regulation-moving to a public value regulation

International Nuclear Information System (INIS)

Mitchell, Catherine; Woodman, Bridget

2010-01-01

The UK Government has committed itself to reducing its carbon dioxide emissions. The challenge of successfully achieving a transition to a sustainable energy system, in the context of the UK's largely privately owned energy industry, rests on the ability of policy makers to encourage and enable the necessary changes or innovation at all levels of the energy system. This paper argues that the UK's current, dominant political paradigm or framework (the regulatory state paradigm (RSP)) and within it, the role of the economic regulator, Ofgem acts as a fundamental block to this challenge. The current economic regulatory system is based on trust in the market, or on predicted (albeit theoretical) known outcomes. To expand our regulatory system to one which can deliver a sustainable energy system requires innovation in a certain direction (as opposed to any innovation). That is the antithesis of the current process of regulation. Trust is required that Ofgem, the economic regulator, will develop rules and incentives which deliver an agreed sustainable energy goal, which is 'trusted' to be the 'right' goal. This requires Ofgem moving away from ex-ante regulation to a type of regulation where all costs, benefits and outcomes cannot be known beforehand and where they cannot necessarily be quantifiable. This has, very provisionally, been called Public Value Regulation (PVR).

Do the services for children offered in Helsinki hotels meet the preferences of family travellers?

OpenAIRE

Fernández, Amelia

2016-01-01

Meeting the needs of family travellers by catering to the children is a way for hotels to attract these profitable guests. The objective of this thesis is to analyse the services offered for children in four Helsinki hotels and evaluate whether they meet the needs and preferences of current domestic and international travellers. The preliminary hypothesis is that the hotels chosen to represent the hotel market in Helsinki offer similar services; that do not meet current traveller preferences....

77 FR 8324 - Sunshine Act Meeting Notice, February 16, 2012

Science.gov (United States)

2012-02-14

... Auditorium at TVA's Chattanooga Office Complex, 1101 Market Street, Chattanooga, Tennessee. The public may... Old Business Approval of minutes of November 17, 2011, Board Meeting New Business 1. Report from... Audit, Risk, and Regulation Committee. 6. Report of the People and Performance Committee. For more...

LQG Controller Design for Pitch Regulated Variable Speed Wind Turbine

DEFF Research Database (Denmark)

Imran, Raja Muhammed; Hussain, Dil Muhammad Akbar; Chen, Zhe

2014-01-01

Variable speed wind turbine is a complex and nonlinear system, a sophisticated control is required to meet the challenges posed by these systems. This paper is presenting a pitch regulation strategy based on LQG (Linear Quadratic Gaussian) to regulate turbine at its rated power and to reject...

Expert Meeting Report: Energy Savings You Can Bank On

Energy Technology Data Exchange (ETDEWEB)

Beman, M.; Springer, J.; Smith, P.; Porse, E.

2013-02-01

In October 2011, ARBI organized and conducted an Experts' Meeting on the topic of performance guarantees and financing vehicles for Energy Efficiency Upgrades. The meeting brought together technical, policy, and financial experts, including researchers, experienced installation contractors, and innovative energy business leaders, in order to discuss the opportunities and challenges for the energy efficiency upgrade industry to increase market uptake of Home Energy Upgrades (HEUs) through innovative offerings, such as performance guarantees. The meeting had several primary goals. First, it sought to understand how other industries have developed successful models for financing renewable energy installations while providing performance guarantees. This has been most recently demonstrated by the solar leasing industry. Second, the meeting explored the applicability of such business models to the energy efficiency upgrade industry. Third, the meeting sought to identify technical impediments to performance guarantees for energy efficiency retrofits. Fourth, the meeting sought to provide a common framework for these goals within the context of current financing mechanisms for energy efficiency upgrades.

76 FR 26252 - Gulf of Mexico Fishery Management Council; Public Meeting

Science.gov (United States)

2011-05-06

... Vessel Monitoring System (VMS) Advisory Panel will meet to discuss operation, design, usage of vessel monitoring systems (VMS), and resulting data from these systems. The Advisory Panel will discuss the current.... SUMMARY: The Gulf of Mexico Fishery Management Council will convene a meeting of the Vessel Monitoring...

Thoughts on How to Regulate Behaviours: An Overview of the Current Debate

Science.gov (United States)

Etienne, Julien

2013-01-01

The article intends to present the debate on behaviour modification in the regulation studies literature, at a time of renewed interest among regulators for new ideas and strategies. As the financial crisis has led to the most public critique yet of the rational choice view of individuals that has informed regulation in the last few decades, other…

Developing New Modelling Tools for Environmental Flow Assessment in Regulated Salmon Rivers

Science.gov (United States)

Geris, Josie; Soulsby, Chris; Tetzlaff, Doerthe

2013-04-01

There is a strong political drive in Scotland to meet all electricity demands from renewable sources by 2020. In Scotland, hydropower generation has a long history and is a key component of this strategy. However, many rivers sustain freshwater communities that have both high conservation status and support economically important Atlantic salmon fisheries. Both new and existing hydropower schemes must be managed in accordance with the European Union's Water Framework Directive (WFD), which requires that all surface water bodies achieve good ecological status or maintain good ecological potential. Unfortunately, long-term river flow monitoring is sparse in the Scottish Highlands and there are limited data for defining environmental flows. The River Tay is the most heavily regulated catchment in the UK. To support hydropower generation, it has an extensive network of inter- and intra- catchment transfers, in addition to a large number of regulating reservoirs for which abstraction legislation often only requires minimum compensation flows. The Tay is also considered as one of Scotland's most important rivers for Atlantic salmon (Salmo salar), and there is considerable uncertainty as to how best change reservoir operations to improve the ecological potential of the river system. It is now usually considered that environmental flows require more than a minimum compensation flow, and instead should cover a range of hydrological flow aspects that represent ecologically relevant streamflow attributes, including magnitude, timing, duration, frequency and rate of change. For salmon, these hydrological indices are of particular interest, with requirements varying at different stages of their life cycle. To meet the WFD requirements, rationally alter current abstraction licences and provide an evidence base for regulating new hydropower schemes, advanced definitions for abstraction limits and ecologically appropriate flow releases are desirable. However, a good understanding

MANAGEMENT BOARD MEETING OF 28 MAY 2001

CERN Multimedia

2001-01-01

Report on the Outcome of TREF's May Meeting J. van der Boon, Director of Administration, briefly reported on the outcome of TREF's first meeting of the year on 18 May. In the framework of follow-up to the 2000 five-yearly review, the Forum had heard status reports on preparations for the implementation of the new career structure on 1 September 2001 and on the introduction of long-term care provisions, and had examined an information document concerning the 0.3% discrepancy in the net salary adjustment on 1 January 2001. Following discussion, it had recommended that a proposal to correct the discrepancy, backdated to 1 January, be submitted to the Finance Committee at its next meeting on 13 June. The Forum had also discussed a set of proposed amendments to the tenth edition of the Staff Rules and Regulations, essentially relating to the implementation of the new career structure and to terminology, as well as a status report on voluntary programmes (Saved Leave, Progressive Retirement and Part-Time Work as a ...

76 FR 51064 - National Science Board; Sunshine Act Meetings; Notice

Science.gov (United States)

2011-08-17

... NATIONAL SCIENCE FOUNDATION National Science Board; Sunshine Act Meetings; Notice The National Science Board (NSB) Committee on Audit and Oversight and the NSB Committee on Strategy and Budget, pursuant to NSF regulations (45 CFR part 614), the National Science Foundation Act, as amended (42 U.S.C...

75 FR 61779 - National Science Board: Sunshine Act Meetings; Notice

Science.gov (United States)

2010-10-06

... Science Board's Committee on Programs and Plans, pursuant to NSF regulations (45 CFR Part 614), the... National Science Board business and other matters specified, as follows: DATE AND TIME: October 13, 2010, 1... Performance Computing Award. STATUS: Closed. LOCATION: This meeting will be held at National Science...

77 FR 5750 - Major Capital Investment Projects (NPRM); Public Meetings

Science.gov (United States)

2012-02-06

...-0009] RIN 2132-AB02 Major Capital Investment Projects (NPRM); Public Meetings AGENCY: Federal Transit... Capital Investments program (``New Starts'' and ``Small Starts''). During these sessions, FTA staff will... amend the regulations for Major Capital Investment Projects at 49 CFR 611. The docket for comments on...

Executive committee report: geotechnical instrumentation working group meeting

International Nuclear Information System (INIS)

Wilder, D.G.; Rogue, F.; Beloff, W.R.; Binnall, E.; Gregory, E.C.

1982-01-01

Responding to the widespread need for the geotechnical community to discuss instrumentation for nuclear waste repositories, a meeting was held December 2 and 3, 1981, in Denver, Colorado. This report gives the group's consensus recommendations to aid in making decisions for development of instrumentation for future repository work. The main conclusions of the working group meeting were as follows: (1) monitoring of geotechnical parameters in nuclear waste repositories will be necessary to meet licensing requirements; (2) currently available instruments are underdeveloped for this monitoring; (3) research and development to provide adequate instrumentation will need to be performed under federal sponsorship by national laboratories, universities, contractors, and consultants; and (4) a NASA-type reliability program is needed to meet the quality assurance, durability, calibration, and time schedule demands of geotechnical instrumentation development. This will require significant financial commitments from the federal sector

A regulator's perspective on physical testing for type B packages

International Nuclear Information System (INIS)

Brach, William E.

2004-01-01

The U.S. Nuclear Regulatory Commission has a great deal of experience certifying Type B transport packages as complying with the regulations in 10 CFR Part 71. With this experience base, supporting risk studies, and with an exceptional historical safety record for transport, we are very confident in both the current regulations and the methods we use to review and certify transportation packages. Nevertheless, we have a responsibility to remain vigilant and review our regulations and implementing practices with a view towards continuous improvement. NRC regulations permit certification through testing, analyses, comparison to similar approved designs, or combinations of these methods. Testing can be further broken into scale models, components, simple models, or full-scale models. NRC does not require full-scale testing for certification of any package; however, many applicants for package certification have conducted a physical testing program to demonstrate that the package design meets the hypothetical accident conditions. The plans for a repository at Yucca Mountain have raised significant interest in the United States of America in transportation of spent fuel, and created a broad stakeholder and public interest in transportation package testing. As an expected large increase in the number of spent fuel transports nears, this interest will likely grow. The technical and regulatory reasons for, or for not, performing tests need to be well understood and communicated to all stakeholders

STANDING CONCERTATION COMMITTEE: ORDINARY MEETINGS ON 5 & 12 MARCH 2004

CERN Document Server

2004-01-01

Original: English These meetings were devoted to the main topics summarised below. 1-Procedure for the award of Long-term Contracts After discussion at several sessions of the SCC, the Committee concluded that a thorough examination of contract policy is required, along the lines of the recommendations presented last year by Internal Task Force 4. However, this study and related changes to the Staff Rules and Regulations will not be completed until the latter part of this year. In the mean time, the Management has proposed to introduce simplified procedures concerning the award of long-term contracts, within the existing Staff Rules and Regulations. The Committee approved these simplified procedures in principle. After final editing of modifications to Administrative Circular no.2 - Guidelines and procedures concerning recruitment and probation period of staff members - and Administrative Circular no.9 - Staff members contracts, they will be submitted to the next meeting of the SCC for approval. 2- MAPS ...

Frontiers of environmental regulation: environmental management systems: a regulator`s perspective

Energy Technology Data Exchange (ETDEWEB)

Stone, M.J. [South Australian Dept. of Mines and Energy, Adelaide, SA (Australia)

1996-12-31

Leading edge companies throughout the world have embraced management systems to achieve optimal sustainable performance in the ever changing business environment of the 1990s. Given that the natural environment and environmental performance have become major issues affecting organizations, the need for integrating environmental management with all the other components of an organization`s overall management approach is now widely recognized. This paper is organized in five parts. The first explores recently released environmental standards, the interim environmental management systems (EMS) general guidelines standard AS/NZS ISO 14004 (Int) and identifies how this has dealt with the regulator/community/company interface. The second identifies company requirements for addressing environmental issues. The third, considers regulatory theory to identify current requirements for an effective regulatory system and how this can interface with a company`s EMS. These form the basis in the fourth section for identifying some opportunities which occur at the company/ regulator interface. The fifth and final section draws a number of conclusions about the current frontiers of environmental regulation. The coincidence of the requirements of a regulatory framework with the areas of interface between what is referred to in the draft International Standard for EMS as `Interested Parties`, the regulators and community, are identified. (author). 1 tab., 2 figs., 20 refs.

SRP scientific meeting: recent legislation - achievements and future challenges, London, 9 October 2001

Energy Technology Data Exchange (ETDEWEB)

Gallani, Barbara

2001-12-01

Full text: The SRP Regulations, Legislation and Standards topic group organised a one-day meeting on 'Recent Legislation - Achievements and Future Challenges' to address the considerable change in the UK radiological protection legislation in recent years. The aim of the meeting was to examine, from the point of view of both the regulators and the users, three of the new regulations: Ionising Radiations Regulations 1999 (IRR99), Ionising Radiations (Medical Exposures) Regulations 2000 (IRMER) and Radiation (Emergency Preparedness and Public Information) Regulations 2001 (REPPIR). The meeting was held in the prestigious lecture theatre of the Royal Institution in London and the 140 delegates had the opportunity, during the day, to visit the Faraday Museum hosted in the building, as well as the stands of the exhibitors. The meeting was divided into a morning session mainly on IRR99 and two afternoon sessions on IRMER and REPPIR, respectively. John Gill (HSE), chairman of the morning session, gave an update on the activities of the SRP Regulations, Legislation and Standards topic group and welcomed all SRP members to participate in the group's work, before introducing the first speaker. Gregg Butler (University of Manchester and Westlakes Research Institute) opened the morning session with a talk on risk, regulation and level playing fields. Gregg expressed his concerns about the implementation of a 'progressive and substantial reduction of discharges' and the possibility of losing a sensible holistic approach to radiological safety issues. He commented on the difficulty of getting a balance between detriment and economic benefit, all historically based on evaluation of doses, when new requirements on radioactive discharges require consideration of activities. He also invited the community to concentrate on 'real problems', like the necessity of making waste more passive, instead of investing money and resources for political reasons

2nd Bayesian Young Statisticians Meeting

CERN Document Server

Bitto, Angela; Kastner, Gregor; Posekany, Alexandra

2015-01-01

The Second Bayesian Young Statisticians Meeting (BAYSM 2014) and the research presented here facilitate connections among researchers using Bayesian Statistics by providing a forum for the development and exchange of ideas. WU Vienna University of Business and Economics hosted BAYSM 2014 from September 18th to 19th. The guidance of renowned plenary lecturers and senior discussants is a critical part of the meeting and this volume, which follows publication of contributions from BAYSM 2013. The meeting's scientific program reflected the variety of fields in which Bayesian methods are currently employed or could be introduced in the future. Three brilliant keynote lectures by Chris Holmes (University of Oxford), Christian Robert (Université Paris-Dauphine), and Mike West (Duke University), were complemented by 24 plenary talks covering the major topics Dynamic Models, Applications, Bayesian Nonparametrics, Biostatistics, Bayesian Methods in Economics, and Models and Methods, as well as a lively poster session ...

Record of the fifth meeting of sub-group B, Vienna, 1 December 1978

International Nuclear Information System (INIS)

1978-12-01

The items discussed included matters arising from the 4th meeting, the collection of basic data, the plutonium recycle (base case), current methods of plutonium transport (base case), the Co-Chairmen's report on the October TCC meeting, current methods of plutonium storage (base case), technological alternatives for plutonium transport and storage, the assessment of base cases, reactor alternatives in the plutonium recycle, and reprocessing alternatives in the plutonium recycle

International Materials Research Meeting in the Greater Region: “Current Trends in the Characterisation of Materials and Surface Modification”

Science.gov (United States)

2017-10-01

Preface Dear ladies and gentlemen, On 6th and 7th of April 2017 took place the “International Materials Research Meeting in the Greater Region” at the Saarland University, Saarbrücken, Germany. This meeting corresponded to the 9th EEIGM International Conference on Advanced Materials Research and it was intended as a meeting place for researchers of the Greater Region as well as their partners of the different cooperation activities, like the EEIGM program, the ‘Erasmus Mundus’ Advanced Materials Science and Engineering Master program (AMASE), the ‘Erasmus Mundus’ Doctoral Program in Materials Science and Engineering (DocMASE) and the CREATe-Network. On this meeting, 72 participants from 15 countries and 24 institutions discussed and exchanged ideas on the latest trends in the characterization of materials and surface modifications. Different aspects of the material research of metals, ceramics, polymers and biomaterials were presented. As a conclusion of the meeting, the new astronaut of the European Space Agency Dr. Matthias Maurer, who is an alumni of the Saarland University and the EEIGM, held an exciting presentation about his activities. Following the publication of selected papers of the 2009 meeting in Volume 5 and 2012 meeting in Volume 31 of this journal, it is a great pleasure to present this selection of 9 articles to the readers of the IOP Conference Series: Materials Science and Engineering. The editors are thankful to all of the reviewers for reviewing the papers. Special praise is also given to the sponsors of the conference: European Commission within the program Erasmus Mundus (AMASE and DocMASE), Erasmus+ (AMASE), and Horizon2020 (CREATe-Network, Grant agreement No 644013): the DAAD (Alumni Program), and the German-French University (PhD-Track). List of Author signatures, Conference topics, Organization, Conference impressions and list of the participants are available in this PDF.

Proceedings of the fuels technology contractors review meeting

Energy Technology Data Exchange (ETDEWEB)

Malone, R.D. [ed.

1993-11-01

The Fuels Technology Contractors Review Meeting was held November 16-18, 1993, at the Morgantown Energy Technology Center (METC) in Morgantown, West Virginia. This meeting was sponsored and hosted by METC, the Office of Fossil Energy, U.S. Department of Energy (DOE). METC periodically provides an opportunity to bring together all of the R&D participants in a DOE-sponsored contractors review meeting to present key results of their research and to provide technology transfer to the active research community and to the interested public. This meeting was previously called the Natural Gas Technology Contractors Review Meeting. This year it was expanded to include DOE-sponsored research on oil shale and tar sands and so was retitled the Fuels Technology Contractors Review Meeting. Current research activities include efforts in both natural gas and liquid fuels. The natural gas portion of the meeting included discussions of results summarizing work being conducted in fracture systems, both natural and induced; drilling, completion, and stimulation research; resource characterization; delivery and storage; gas to liquids research; and environmental issues. The meeting also included project and technology summaries on research in oil shale, tar sands, and mild coal gasification, and summaries of work in natural-gas fuel cells and natural-gas turbines. The format included oral and poster session presentations. Individual papers have been processed separately for inclusion in the Energy Science and Technology database.

Current standardisation for nanotechnology

International Nuclear Information System (INIS)

Bard, Delphine; Mark, David; Moehlmann, Carsten

2009-01-01

Standardisation and standards provide an important mechanism to support both innovation and the application of regulations. There is currently no specific regulation for any nanomaterials. Health, safety and environmental protection aspects associated with nanomaterials are however in principle covered to different levels by current EU regulatory framework. There are a number of national, European and international organisations developing standards associated with the development, description and use of nanomaterials as well as the protection of human health and the environment from the production and use of chemicals and consumer products, including nanomaterials. These organisations have also established specific committees on nanotechnology. This paper outlines the different relevant regulations and standards. This paper will mainly be focused on a European health and safety perspective.

75 FR 48996 - National Science Board; Sunshine Act Meetings; Notice

Science.gov (United States)

2010-08-12

... NATIONAL SCIENCE FOUNDATION National Science Board; Sunshine Act Meetings; Notice The National Science Board's Committee on Audit & Oversight, pursuant to NSF regulations (45 CFR part 614), the National Science Foundation Act, as amended (42 U.S.C. 1862n-5), and the Government in the Sunshine Act (5...

76 FR 3180 - National Science Board; Sunshine Act Meetings; Notice

Science.gov (United States)

2011-01-19

... NATIONAL SCIENCE FOUNDATION National Science Board; Sunshine Act Meetings; Notice The National Science Board's Committee on Programs and Plans and the Committee on Audit & Oversight, pursuant to NSF regulations (45 CFR part 614), the National Science Foundation Act, as amended (42 U.S.C. 1862n-5), and the...

Technologies for improving the availability and reliability of current and future water cooled nuclear power plants. Proceedings of a technical committee meeting

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-11-01

One of the activities of the IAEA is to provide all Member States with an international source of balanced, objective information on advanced in technology for water cooled reactors. Since the global nuclear industry has a common interest in improving plant availability and reliability to assure specific individual plant and country perspective as well as to have an image of well managed competitive industry, the IAEA held a Technical Committee Meeting on Technologies for Improving the Availability and Reliability of Current and Future Water Cooled Nuclear Power Plants in September 1997. The basic aim to was to identify, review and exchange information on international developments in technologies for achieving high availability and reliability and to suggest areas where further technical advances could contribute to improvement of performance. Designs for future plants were presented in the context of how they can accommodate both the organizational and technical means for reaching even higher levels of performance. This proceedings contains the contributed papers presented at this Meeting each with a separate abstract. Four sessions were concerned with: policies, practices and procedures for achieving high reliability and availability; improving availability and reliability through better use of today`s technologies; recent advances in technologies for improving availability and reliability; achieving high availability for new plants Refs, figs, tabs

Technologies for improving the availability and reliability of current and future water cooled nuclear power plants. Proceedings of a technical committee meeting

International Nuclear Information System (INIS)

1998-11-01

One of the activities of the IAEA is to provide all Member States with an international source of balanced, objective information on advanced in technology for water cooled reactors. Since the global nuclear industry has a common interest in improving plant availability and reliability to assure specific individual plant and country perspective as well as to have an image of well managed competitive industry, the IAEA held a Technical Committee Meeting on Technologies for Improving the Availability and Reliability of Current and Future Water Cooled Nuclear Power Plants in September 1997. The basic aim to was to identify, review and exchange information on international developments in technologies for achieving high availability and reliability and to suggest areas where further technical advances could contribute to improvement of performance. Designs for future plants were presented in the context of how they can accommodate both the organizational and technical means for reaching even higher levels of performance. This proceedings contains the contributed papers presented at this Meeting each with a separate abstract. Four sessions were concerned with: policies, practices and procedures for achieving high reliability and availability; improving availability and reliability through better use of today's technologies; recent advances in technologies for improving availability and reliability; achieving high availability for new plants

STANDING CONCERTATION COMMITTEE ORDINARY MEETING HELD ON 26 MAY AND 2 JUNE 1999

CERN Multimedia

1999-01-01

Original: FrenchThe meeting was devoted essentially to examining the various items listed below:TREF meeting on 28 May 1999The items on this meeting's agenda were: a status report on the voluntary programmes, the Forum's work planning and in particular preparation for the five-yearly review of financial conditions, and the scope of application of Article R IV 1.25 of the Staff Regulations concerning the reimbursement of taxes to certain categories of students and associates.At the SCC's meeting on 26 May, the Committee members finalised the documents to be submitted to TREF, in particular the Forum's work planning and preparation for the five-yearly review.At its meeting on 2 June, the SCC took note of the results of TREF's meeting and the preparations for the next Finance Committee meeting and Council session in June:Status report on the voluntary programmesThe Forum had regarded the results of these programmes as very positive, especially those of the RSL Programme, which had made it possible to open 36 pos...

Reflections on Competition, Competition Regulation and the Current Crises

DEFF Research Database (Denmark)

Buch-Hansen, Hubert; Wigger, Angela

2013-01-01

competition came to enjoy such an exalted status in Europe and then challenges conventional wisdom by bringing into focus the downsides of competition. It argues that excessive competition and neoliberal competition regulation have contributed to intensify the economic, political, social and environmental...

76 FR 28216 - Meeting of the Chief of Naval Operations Executive Panel

Science.gov (United States)

2011-05-16

... Sponsorship Subcommittee study. The meeting will consist of discussions regarding the current Navy functional organization and the effectiveness and efficiency of its resulting Program Objective Memorandum (POM) versus other previous and potential future organizational structures. DATES: The meeting will be held on May 31...

Impaired Na⁺-dependent regulation of acetylcholine-activated inward-rectifier K⁺ current modulates action potential rate dependence in patients with chronic atrial fibrillation.

Science.gov (United States)

Voigt, Niels; Heijman, Jordi; Trausch, Anne; Mintert-Jancke, Elisa; Pott, Lutz; Ravens, Ursula; Dobrev, Dobromir

2013-08-01

Shortened action-potential duration (APD) and blunted APD rate adaptation are hallmarks of chronic atrial fibrillation (cAF). Basal and muscarinic (M)-receptor-activated inward-rectifier K(+) currents (IK1 and IK,ACh, respectively) contribute to regulation of human atrial APD and are subject to cAF-dependent remodeling. Intracellular Na(+) ([Na(+)]i) enhances IK,ACh in experimental models but the effect of [Na(+)]i-dependent regulation of inward-rectifier K(+) currents on APD in human atrial myocytes is currently unknown. Here, we report a [Na(+)]i-dependent inhibition of outward IK1 in atrial myocytes from sinus rhythm (SR) or cAF patients. In contrast, IK,ACh activated by carbachol, a non-selective M-receptor agonist, increased with elevation of [Na(+)]i in SR. This [Na(+)]i-dependent IK,ACh regulation was absent in cAF. Including [Na(+)]i dependence of IK1 and IK,ACh in a recent computational model of the human atrial myocyte revealed that [Na(+)]i accumulation at fast rates inhibits IK1 and blunts physiological APD rate dependence in both groups. [Na(+)]i-dependent IK,ACh augmentation at fast rates increased APD rate dependence in SR, but not in cAF. These results identify impaired Na(+)-sensitivity of IK,ACh as one potential mechanism contributing to the blunted APD rate dependence in patients with cAF. This article is part of a Special Issue entitled "Na(+) Regulation in Cardiac Myocytes". Copyright © 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.

Electrical installations and regulations

CERN Document Server

Whitfield, J F

1966-01-01

Electrical Installations and Regulations focuses on the regulations that apply to electrical installations and the reasons for them. Topics covered range from electrical science to alternating and direct current supplies, as well as equipment for providing protection against excess current. Cables, wiring systems, and final subcircuits are also considered, along with earthing, discharge lighting, and testing and inspection.Comprised of 12 chapters, this book begins with an overview of electrical installation work, traits of a good electrician, and the regulations governing installations. The r

78 FR 2961 - Sunshine Act Meeting-Closed Meeting

Science.gov (United States)

2013-01-15

... COMMODITY FUTURES TRADING COMMISSION Sunshine Act Meeting--Closed Meeting The following notice of a closed meeting is published pursuant to the provisions of the Government in the Sunshine Act, Public Law 94- 409, 5 U.S.C. 552b. AGENCY HOLDING THE MEETING: Commodity Futures Trading Commission. TIME...

78 FR 6306 - Sunshine Act Meeting-Closed Meeting

Science.gov (United States)

2013-01-30

... COMMODITY FUTURES TRADING COMMISSION Sunshine Act Meeting--Closed Meeting The following notice of a closed meeting is published pursuant to the provisions of the Government in the Sunshine Act, Public Law 94- 409, 5 U.S.C. 552b. AGENCY HOLDING THE MEETING: Commodity Futures Trading Commission. TIME...

Energy policy conference on the regulation of energy industries; Conference de politique energetique sur la regulation des industries energetiques

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-11-01

This document is the report of the conference meeting jointly organized by the French general plan commission and the general direction of energy and raw materials on the regulation of energy industries: 1 - the changes in the regulation of public utilities in competition: harmonization, respect of impartiality and social cohesion, organization of a loyal competition, specialized regulation and regulation of competition, open debates; 2 - towards an homogenous model of regulatory authority?: the US model (collegial and hybrid organizations), the UK model (individual and independent), missions of regulation and institutional 'meccano', theory and practice, draft classification of the institutional approaches of IEA countries (role of ministries and regulatory agencies), independent regulatory authorities or not, significant differences in converging models, dominant types of regulation in the different sectors, situation of the French energy regulatory system (institutional plan, regulation processes, relations of the regulation authority with the government), reasons of the differences between different countries, expected evolution of the regulation systems in the coming years. (J.S.)

Energy policy conference on the regulation of energy industries; Conference de politique energetique sur la regulation des industries energetiques

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-11-01

This document is the report of the conference meeting jointly organized by the French general plan commission and the general direction of energy and raw materials on the regulation of energy industries: 1 - the changes in the regulation of public utilities in competition: harmonization, respect of impartiality and social cohesion, organization of a loyal competition, specialized regulation and regulation of competition, open debates; 2 - towards an homogenous model of regulatory authority?: the US model (collegial and hybrid organizations), the UK model (individual and independent), missions of regulation and institutional 'meccano', theory and practice, draft classification of the institutional approaches of IEA countries (role of ministries and regulatory agencies), independent regulatory authorities or not, significant differences in converging models, dominant types of regulation in the different sectors, situation of the French energy regulatory system (institutional plan, regulation processes, relations of the regulation authority with the government), reasons of the differences between different countries, expected evolution of the regulation systems in the coming years. (J.S.)

Lipid droplet meets a mitochondrial protein to regulate adipocyte lipolysis

Science.gov (United States)

In response to adrenergic stimulation, adipocytes undergo protein kinase A (PKA)-stimulated lipolysis. A key PKA target in this context is perilipin 1, a major regulator of lipolysis on lipid droplets (LDs). A study published in this issue of The EMBO Journal (Pidoux et al, 2011) identifies optic at...

Constructing regulation and regulating for energy efficient construction

Energy Technology Data Exchange (ETDEWEB)

Shove, Elizabeth [Lancaster University (United Kingdom). Centre for the Study of Environmental Change

1998-07-01

This project considers the process of formulating energy-related building regulation in the light of the revisions to Part L (Conservation of Fuel and Power) of the Building Regulations for England and Wales. Details are given of the main objectives of the research, namely, the examination of the roles of the UK government, local government and pressure groups in shaping energy efficiency standards, the impacts of environmental regulations, the limits of energy-related regulation, environmental regulation of the building sector, and the features of energy related building control. This control is compared with current practice in other European countries. The methodology of the project involving the review of governmental documents and interviews is described. (UK)

The activity of spontaneous action potentials in developing hair cells is regulated by Ca(2+-dependence of a transient K+ current.

Directory of Open Access Journals (Sweden)

Snezana Levic

Full Text Available Spontaneous action potentials have been described in developing sensory systems. These rhythmic activities may have instructional roles for the functional development of synaptic connections. The importance of spontaneous action potentials in the developing auditory system is underpinned by the stark correlation between the time of auditory system functional maturity, and the cessation of spontaneous action potentials. A prominent K(+ current that regulates patterning of action potentials is I(A. This current undergoes marked changes in expression during chicken hair cell development. Although the properties of I(A are not normally classified as Ca(2+-dependent, we demonstrate that throughout the development of chicken hair cells, I(A is greatly reduced by acute alterations of intracellular Ca(2+. As determinants of spike timing and firing frequency, intracellular Ca(2+ buffers shift the activation and inactivation properties of the current to more positive potentials. Our findings provide evidence to demonstrate that the kinetics and functional expression of I(A are tightly regulated by intracellular Ca(2+. Such feedback mechanism between the functional expression of I(A and intracellular Ca(2+ may shape the activity of spontaneous action potentials, thus potentially sculpting synaptic connections in an activity-dependent manner in the developing cochlea.

Standing Concertation Committee - Ordinary Meeting on 15 January 2005

CERN Multimedia

2005-01-01

This meeting was devoted to the main topics summarised below. Follow-up from the meetings of the Finance Committee and Council in December 2004 The Chairman welcomed two new SCC members representing the Staff Association: Véronique Paris and Gianni Deroma. Expressing their best wishes for the New Year, the members of the SCC took note of a report by the Chairman on the outcome of these Committee meetings and of the Director-General's staff meeting on 10 January 2005, and discussed a number of internal follow-up actions. Work planning of the SCC & TREF The SCC agreed its calendar of ordinary sessions and its draft work planning for the first half of 2005, subject to including a number of matters outstanding from 2004. The Committee discussed internal preparation for the next meeting of TREF on 4 & 5 April devoted to items concerning the current 5-Yearly Review. The SCC also took note of the provisional scheduling of TREF meetings from May to September, which will be settled by...

California's privacy pileup. New state laws meet even newer federal regulations.

Science.gov (United States)

Dimick, Chris

2009-08-01

In California, teasing apart state and federal breach notification laws highlights the challenges organizations everywhere face in determining their responsibilities under ARRA's new privacy regulations.

75 FR 47030 - National Science Board; Sunshine Act Meetings; Notice

Science.gov (United States)

2010-08-04

... Committee on Programs and Plans. STATUS: Open. LOCATION: This meeting will be held by teleconference... Programs and Plans, pursuant to NSF regulations (45 CFR part 614), the National Science Foundation Act, as... business and other matters specified, as follows: DATE AND TIME: August 12, 2010 at 3 p.m. EDT. SUBJECT...

Cued Retrospective Reporting: Measuring Self-Regulated Learning

NARCIS (Netherlands)

Van Meeuwen, Ludo; Brand-Gruwel, Saskia; Kirschner, Paul A.; De Bock, Jeano; Van Merriënboer, Jeroen

2012-01-01

Van Meeuwen, L. W., Brand-Gruwel, S., Kirschner, P. A., De Bock, J. J. P. R., & Van Merriënboer, J. J. G. (2012, april). Cued retrospective reporting: Measuring self-regulated learning. Paper presented at the AERA annual meeting, Vancouver, B. C.

Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia

OpenAIRE

Jason, Leonard A; McManimen, Stephanie; Sunnquist, Madison; Newton, Julia L; Strand, Elin Bolle

2017-01-01

The Institute of Medicine (IOM) recently developed clinical criteria for chronic fatigue syndrome (CFS). There might be additional criteria that could select a more homogenous and impaired group of patients, particularly those with pain. The current study focused on criteria which involved meeting the four IOM criteria, excluding medical and psychiatric co-morbidities, along with having fibromyalgia (FM). Findings indicated that those meeting the IOM clinical criteria plus FM were more impair...

41 CFR 102-76.25 - What standards must Federal agencies meet in providing architectural and interior design services?

Science.gov (United States)

2010-07-01

... Federal agencies meet in providing architectural and interior design services? 102-76.25 Section 102-76.25...) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 76-DESIGN AND CONSTRUCTION Design and Construction § 102-76.25 What standards must Federal agencies meet in providing architectural and interior design services...

Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia.

Science.gov (United States)

Jason, Leonard A; McManimen, Stephanie; Sunnquist, Madison; Newton, Julia L; Strand, Elin Bolle

2017-01-01

The Institute of Medicine (IOM) recently developed clinical criteria for chronic fatigue syndrome (CFS). There might be additional criteria that could select a more homogenous and impaired group of patients, particularly those with pain. The current study focused on criteria which involved meeting the four IOM criteria, excluding medical and psychiatric co-morbidities, along with having fibromyalgia (FM). Findings indicated that those meeting the IOM clinical criteria plus FM were more impaired on a wide variety of symptoms and functional areas than those meeting on the IOM criteria or those with just 6 months of fatigue. The implications of using such research criteria are discussed.

Standing Concertation Committee - Ordinary meeting on 2 March 2005

CERN Multimedia

2005-01-01

Original: English This meeting was devoted to the main topics summarised below. 1. MAPS - Preparation for the 2005 exercise The SCC agreed the text of the ‘2005 Guidelines for Advancement and Promotion', subject to some amendments. (See Official News Article below) As regards the numerical budgetary guidelines for this year's exercise, the Chairman announced that the Management agreed to grant 30 additional steps as a transitional measure, which had also been the case for the 2003 and 2004 exercises. 2. Annual carry-over of leave (Article R II 4.07 of the Staff Regulations) The SCC examined the Management's proposal to increase the possibility of carry-over of annual leave (currently 30 days) from one leave year to the next, up to the end of the 2007 / 2008 leave year. After some discussion, it was agreed to limit this supplementary carry-over of leave to 10 days* and to exceptional cases only, essentially concerning crucial LHC activities. Such cases would be subject to approval by the hierar...

Sterilization processes. Meeting the demands of today's health care technology.

Science.gov (United States)

Crow, S

1993-09-01

Universal Precautions dictate sterilization for all invasive equipment that break the blood barrier; however, current methods of sterilization, such as steam and ethylene oxide gas (ETO), are not compatible with many of the delicate, heat-sensitive surgical instruments used in modern health care. In addition, traditional sterilization methods are often too time consuming for practical use in the operating room. Clearly, new sterilization processes need to be developed. In this article, the criteria modern sterilization processes must meet and how some manufacturers plan to meet this challenge are discussed. In addition, the pros and cons of using peracetic acid (the newest sterilization process currently available) are examined.

Incentive regulation of nuclear power plants by state regulators

International Nuclear Information System (INIS)

Martin, R.L.; Baker, K.; Olson, J.

1991-02-01

The Nuclear Regulatory Commission (NRC) monitors incentive programs established by state regulators in order to obtain current information and to consider the potential safety effects of the incentive programs as applied to nuclear units. The current report is an update of NUREG/CR-5509, Incentive Regulation of Nuclear Power Plants by State Public Utility Commissions, published in December 1989. The information in this report was obtained from interviews conducted with each state regulator and each utility with a minimum entitlement of 10%. The agreements, orders, and settlements from which each incentive program was implemented were reviewed as required. The interviews and supporting documentation form the basis for the individual state reports describing the structure and financial impact of each incentive program. The programs currently in effect represent the adoption of an existing nuclear performance incentive program proposal and one new program. In addition, since 1989 a number of nuclear units have been included in one existing program; while one program was discontinued and another one concluded. 6 refs., 27 tabs

Meeting Disorders.

Science.gov (United States)

Yager, Joel; Katzman, Jeffrey W

2017-12-01

Although meetings are central to organizational work, considerable time devoted to meetings in Academic Health Centers appears to be unproductively spent. The primary purposes of this article are to delineate and describe Meeting Disorders, pathological processes resulting in these inefficient and ineffective scenarios, and Meeting Fatigue Disorder (MFD), a clinical syndrome. The paper also offers preliminary approaches to remedies. The authors integrate observations made during tens of thousands of hours in administrative meetings in academic medical settings with information in the literature regarding the nature, causes and potential interventions for dysfunctional groups and meetings. Meeting Disorders, resulting from distinct pathologies of leadership and organization, constitute prevalent subgroups of the bureaucrapathologies, pathological conditions caused by dysfunctional bureaucratic processes that generate excesses of wasted time, effort, and other resources. These disorders also generate frustration and demoralization among participants, contributing to professional burnout. Meeting Fatigue Disorder (MFD) is a subjective condition that develops in individuals who overdose on these experiences and may reflect one manifestation of burnout. Meeting disorders and Meeting Fatigue Disorder occur commonly in bureaucratic life. Resources and potential remedies are available to help ameliorate their more deleterious effects.

75 FR 9083 - Notice of Open Meeting

Science.gov (United States)

2010-02-26

... examine the causes, domestic and global, of the current financial and economic crisis in the United States... Part IV Financial Crisis Inquiry Commission Notice of Open Meeting; Notice #0;#0;Federal Register / Vol. 75 , No. 38 / Friday, February 26, 2010 / Notices#0;#0; [[Page 9084

Overview of the current National Primary Drinking Water Regulations and regulation development process

International Nuclear Information System (INIS)

Cotruvo, J.A.; Regelski, M.

1989-01-01

The promulgation of the National Primary Drinking Water Regulations (NPDWR) follows specific steps. First, the Advance Notice of Proposed Rule Making (ANPRM) is published. Second, the EPA, as mandated by the SDWA Amendments, proposes maximum contaminant levels (MCLs), (enforceable standards) and maximum contaminant level goals (MCLGs) simultaneously. The Office of Drinking Water developed a six-phase schedule that has attempted to parallel the SDWA-specified deadlines: Phase I - Voltile organic chemicals - July 8, 1987; Phase II - Synthetic organic chemicals and inorganic chemicals - June 1989, microbials and surface water treatment - June 1989, and Lead/copper - December 1988; Phase III - Radionuclides - December 1988; Phase IV - Disinfectants and disinfection by-products - June 1989; Phase V - Other inorganic chemicals, synthetic organic chemicals, and pesticides - June 1989; and Phase VI - 25 additional chemicals - January 199. In selecting contaminants for regulation, the most relevant criteria are (1) potential health risk; (2) ability to detect a contaminant in the drinking water; and (3) occurrence or potential occurrence in drinking water. The EPA uses a three category approach for setting maximum contaminant level goals for carcinogens: Category I, strong evidence of carcinogenicity-zero; Category II, equivocal evidence - reference dose (RfD) approach or 0.00001 to 0.000001 cancer risk range; and Category III, inadequate or no evidence from animal studies - RfD approach. 10 refs., 5 tabs

[Current issues in legal cases of compensation for healthcare malpractice].

Science.gov (United States)

Heiner, Tamás; Barzó, Tímea

2014-09-21

The number of medical malpractice lawsuits filed each year in Hungary has considerably increased since 1990. The judicial decisions and practices on determining and awarding wrongful damages recoverable for medical malpractices in the Hungarian civil law have been developing for decades. In the meantime, a new Hungarian Civil Code (Act V of 2013) has entered into force, which among others, necessitates the revaluation of assessment of damages recoverable for medical malpractices. There are two main areas where fundamental changes have been introduced, which may significantly affect the outcome of medical malpractice lawsuits in the future. In the early stage of medical malpractices it was unclear whether the courts had to consider either the contractual relationship between patients and healthcare providers (contractual liability) or general codal articles on damages arising from non-contractual liability/torts (delictual liability) in their judgement delivered in the cases. Both the theoretical and practical experience of the last ten years shows that healthcare services agreements are concluded between healthcare providers and patients with the aim and intention to provide appropriate professional healthcare services to patients, which meet patients' interests and wishes. The medical service is violated if it fails to meet patients' interests and wishes as well as the objectives of the agreement. Since the new legislation implies a stricter liability for damages in the case of breach of contract and stricter rules for exempting the party in breach from compensation obligations, the opportunities to exempt healthcare providers from these obligations have become limited compared to previous regulations. This modification, which was aimed at further integrating the established judicial practices into legislation, stipulates the application of the rules for liability for damages resulting from medical malpractice in non-contractual situations. This paper analyses

The future of gas and major current events

International Nuclear Information System (INIS)

Anon.

2007-01-01

Natural gas market has been completely open in France since July 1, 2007. Long-time operators like Gaz de France (GdF) and local distribution companies, have adapted to the new constraints mainly by meeting the requirement to separate the infrastructure business from the commercial activities. Newcomers, mostly well-known foreign companies, have joined the traditional operators. Overall, the French market is working well, rules have been implemented and are being adequately enforced. To support these changes, the French gas industry needs a recognised professional association. The French gas association (AFG) fills this role, and promotes the image of gas through various events, congresses and meetings. This paper expresses the AFG's position concerning the future of gas in relation to major current events: AFG estimates that gas should play a full role in the energy spectrum based on its unique properties and wishes that public authorities take into consideration all features of all energy sources in their strategies, in particular CO 2 emissions all along the energy processes. AFG requests public authorities to set up fair, motivative and stable operating rules at least to the medium term. AFG would like the Energy regulating committee (CRE) to set an investment return rate that gives investors a sufficient incentive without penalizing the gas consumer. The AFG requests also that the administrative procedures for investment are simplified, with clarified rules and a fast arbitration for not delaying the opening of infrastructures. (J.S.)

Single-Family Houses That Meet The Future Energy Demands

DEFF Research Database (Denmark)

Rose, Jørgen; Svendsen, Svend

2002-01-01

). Before any further tightening of the regulations are introduced, however, it is necessary to illustrate the consequences of such actions with regard to finance, building technology, indoor climate and comfort. Therefore a series of investigations and experimental projects are being launched, in order...... to examine these consequences thoroughly. The department is presently contributing to this end by participating in quite a few investigative projects, where single-family houses are designed to meet the proposed future energy demands. This paper describes the results obtained from one such project where...... the department, in co-operation with a major building entrepreneur, has developed a single-family house that shows that there are no evident problems in meeting the future energy demands....

LNG. Practice and policy. Meeting report NeVER, November 20, 2006

International Nuclear Information System (INIS)

Holzhauer, R.W.

2007-01-01

Report is given of a meeting of the Netherlands Association for Energy Legislation (NeVER), which was held November 16, 2006, in Amsterdam, on the subject of LNG. More in particular third party access to LNG-terminals and related exemption regulations in Europe and the Netherlands [nl

Emotion regulation and mental health: recent findings, current challenges, and future directions.

Science.gov (United States)

Berking, Matthias; Wupperman, Peggilee

2012-03-01

In recent years, deficits in emotion regulation have been studied as a putative maintaining factor and promising treatment target in a broad range of mental disorders. This article aims to provide an integrative review of the latest theoretical and empirical developments in this rapidly growing field of research. Deficits in emotion regulation appear to be relevant to the development, maintenance, and treatment of various forms of psychopathology. Increasing evidence demonstrates that deficits in the ability to adaptively cope with challenging emotions are related to depression, borderline personality disorder, substance-use disorders, eating disorders, somatoform disorders, and a variety of other psychopathological symptoms. Unfortunately, studies differ with regard to the conceptualization and assessment of emotion regulation, thus limiting the ability to compare findings across studies. Future research should systematically work to use comparable methods in order to clarify the following: which individuals have; what kinds of emotion regulation difficulties with; which types of emotions; and what interventions are most effective in alleviating these difficulties. Despite some yet to be resolved challenges, the concept of emotion regulation has a broad and significant heuristic value for research in mental health.

41st Annual Meeting of the Spanish Nuclear Society

Energy Technology Data Exchange (ETDEWEB)

NONE

2015-07-01

The Spanish Nuclear Society (SNE) is a non-profit association, made up of professionals and institutions, in order to promote awareness and dissemination of nuclear science and technology. The 41 Annual Meeting of the Spanish Nuclear Society was held in A Coruña from 23 to 25 September 2015. This Annual Meeting allows professionals and companies in the sector to analyze the current state of nuclear energy and its future challenges, covering different topics from engineering to R & D, nuclear safety, also impact on health and the environment, climate change, nuclear facilities, experience spanish companies in the management of knowledge in the nuclear sector. This congress has involved some 600 experts who have dealt with current issues and maximum interest.

Standing Concertation Committee - Ordinary Meeting on 2 August 2005

CERN Multimedia

2005-01-01

Original : English This meeting was devoted to the main items summarised below. New Contract Policy for staff members The SCC took note of Council's approval last June of the Management's proposal to introduce a new contract policy for staff members, on the understanding that the necessary amendments to the Staff Rules and Regulations would be submitted for approval this autumn with a view to their coming into effect at the beginning of 2006. The SCC then proceeded to examine detailed implementation measures and agreed that the Management would draw up the necessary documents on this basis, including provisions concerning transitional measures, for discussion at SCC as soon as possible. Pension Fund matters It has now been confirmed that the next meeting of TREF on 12 & 13 September will be devoted to matters concerning the Pension Fund. In preparation for that meeting, the SCC examined a document from the Governing Board of the Pension Fund concerning “Compensation to the Pension Fund for the r...

Seventh meeting of the ITER physics expert group on energetic particles, heating and steady state operations

International Nuclear Information System (INIS)

Gormezano, C.

1999-01-01

The seventh meeting of the ITER Physics Group on energetic particles, heating and steady state operation was held at CEN/Cadarache from 14 to 18 September 1999. This was the first meeting following the redefinition of the Expert Group structure and it was also the first meeting without participation of US physicists. The main topics covered were: 1. Energetic Particles, 2. Ion Cyclotron Resonance Heating, 3. Lower Hybrid Current Drive, 4. Electron Cyclotron Resonance Heating and Current Drive, 5. Neutral Beam Injection, 6. Steady-State Aspects

75 FR 73083 - Sunshine Act Meeting; Open Commission Meeting

Science.gov (United States)

2010-11-29

... FEDERAL COMMUNICATIONS COMMISSION Sunshine Act Meeting; Open Commission Meeting November 30, 2010. The Federal Communications Commission will hold an Open Meeting on the subjects listed below on... demonstrate accessibility technologies. The meeting site is fully accessible to people using wheelchairs or...

Meeting Quay 2k30's requirements

NARCIS (Netherlands)

Wijnants, G.H.; Toorn, A. van der; Schuylenburg, M.; Heijnen, H.P.J.; Gijt, J.G. de; Molenaar, W.F.; Ligteringen, H.; Krom, A.H.M.

2005-01-01

The requirements that a quay design should meet in order to yield a viable port infrastructure, vary widely from flexibility due to future customers requirements to durability due to owners requirements. In a Port of Rotterdam backed project, current and future requirements have been aggregated by

Direct Interaction of CaVβ with Actin Up-regulates L-type Calcium Currents in HL-1 Cardiomyocytes*

Science.gov (United States)

Stölting, Gabriel; de Oliveira, Regina Campos; Guzman, Raul E.; Miranda-Laferte, Erick; Conrad, Rachel; Jordan, Nadine; Schmidt, Silke; Hendriks, Johnny; Gensch, Thomas; Hidalgo, Patricia

2015-01-01

Expression of the β-subunit (CaVβ) is required for normal function of cardiac L-type calcium channels, and its up-regulation is associated with heart failure. CaVβ binds to the α1 pore-forming subunit of L-type channels and augments calcium current density by facilitating channel opening and increasing the number of channels in the plasma membrane, by a poorly understood mechanism. Actin, a key component of the intracellular trafficking machinery, interacts with Src homology 3 domains in different proteins. Although CaVβ encompasses a highly conserved Src homology 3 domain, association with actin has not yet been explored. Here, using co-sedimentation assays and FRET experiments, we uncover a direct interaction between CaVβ and actin filaments. Consistently, single-molecule localization analysis reveals streaklike structures composed by CaVβ2 that distribute over several micrometers along actin filaments in HL-1 cardiomyocytes. Overexpression of CaVβ2-N3 in HL-1 cells induces an increase in L-type current without altering voltage-dependent activation, thus reflecting an increased number of channels in the plasma membrane. CaVβ mediated L-type up-regulation, and CaVβ-actin association is prevented by disruption of the actin cytoskeleton with cytochalasin D. Our study reveals for the first time an interacting partner of CaVβ that is directly involved in vesicular trafficking. We propose a model in which CaVβ promotes anterograde trafficking of the L-type channels by anchoring them to actin filaments in their itinerary to the plasma membrane. PMID:25533460

Technologies for improving current and future light water reactor operation and maintenance: Development on the basis of experience. Proceedings of a technical committee meeting

International Nuclear Information System (INIS)

2000-09-01

Application of efficient technologies for improving operation and maintenance of nuclear power plants is an important element for assuring their economic competitiveness with other means of generating electricity. The competitive environment, which nuclear power plant operators face in many countries as a result of de-regulation of the electricity market, imposes cost pressures that must be met while at the same time satisfying stringent safety requirements. Further, as currently operating plants age, proper management includes development and application of better technologies for inspection, maintenance and repair. For future plants, the opportunity exists during the design phase to incorporate design features for performing efficient inspection, maintenance and repairs. Despite the prevailing low prices of fossil fuels, the generation costs of nuclear electricity continue to be competitive with electricity generation costs from fossil-fuelled plants for base load generation in several countries. For nuclear power, the capital investment component of electricity generation cost is relatively high, while the nuclear fuel cycle cost is - and is expected to remain - relatively low. The prices of fossil fuels are fairly low today but are likely to increase over the long term because the resource is limited. Moreover, governments may introduce incentives to reduce the use of fossil fuels in order to protect the environment. In many countries, nuclear utilities are experiencing increased competition with other sources of electricity production due to deregulation of the electricity market, and nuclear plant operators can no longer pass along the generation costs to consumers through regulated electricity rates. This competitive environment has significant implications for plant operations to achieve efficient use of all resources, and to effectively manage plant activities including outages and maintenance. Over the past several years, steady improvements have been

Technologies for improving current and future light water reactor operation and maintenance: Development on the basis of experience. Proceedings of a technical committee meeting

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-09-01

Application of efficient technologies for improving operation and maintenance of nuclear power plants is an important element for assuring their economic competitiveness with other means of generating electricity. The competitive environment, which nuclear power plant operators face in many countries as a result of de-regulation of the electricity market, imposes cost pressures that must be met while at the same time satisfying stringent safety requirements. Further, as currently operating plants age, proper management includes development and application of better technologies for inspection, maintenance and repair. For future plants, the opportunity exists during the design phase to incorporate design features for performing efficient inspection, maintenance and repairs. Despite the prevailing low prices of fossil fuels, the generation costs of nuclear electricity continue to be competitive with electricity generation costs from fossil-fuelled plants for base load generation in several countries. For nuclear power, the capital investment component of electricity generation cost is relatively high, while the nuclear fuel cycle cost is - and is expected to remain - relatively low. The prices of fossil fuels are fairly low today but are likely to increase over the long term because the resource is limited. Moreover, governments may introduce incentives to reduce the use of fossil fuels in order to protect the environment. In many countries, nuclear utilities are experiencing increased competition with other sources of electricity production due to deregulation of the electricity market, and nuclear plant operators can no longer pass along the generation costs to consumers through regulated electricity rates. This competitive environment has significant implications for plant operations to achieve efficient use of all resources, and to effectively manage plant activities including outages and maintenance. Over the past several years, steady improvements have been

Current products and future plan of regulatory research for risk-informed regulation in Korea

International Nuclear Information System (INIS)

Sung, Key Yong; Lee, Chang Ju; Kim, Woong Sik; Kim, Hho Jung

2003-01-01

The first phase of a regulatory research project for risk-informed regulation (RIR) and applications (RIA) was finished in March of 2002. Various results that could be useful for preparing Korean RIR system have been developed. One of the remarkable outputs is development of reactor safety goals and acceptance criteria for RIR and RIA in Korea. The Safety Goal has a 4-tier hierarchical structure and each tier has specified goals classified for their usage. Regulatory review guides for probabilistic safety assessment (PSA) including level-1, level-2 and low power and shutdown PSA have been updated by reflecting new information obtained from not only the overseas documents but also experience and insights from regulatory review in Korea. In addition, draft regulatory guides for risk-informed in-service inspection, in-service testing, importance ranking of motor-operated valves, and AOT/STI change of Technical Specifications have been developed for preparing ongoing and future licensing work. Risk-based inspection guides with inspection items selected from a viewpoint of risk importance have been suggested for Korean standard NPPs as well. In the second phase of a research project (April of 2002 to March of 2005), two regulatory research projects on RIR were initiated. One is a study on institutionalization of risk-informed and performance-based regulation. Main topics of this project are evaluation of benefit and characteristics of RIR, development of optimized Korean RIR model, impact analysis for the change of current regulation framework, and suggestion of RIR-related laws and rules. The other is focusing on the development in the areas of a regulatory audit PSA model and regulatory guides for risk monitoring, and application techniques of risk information to the significance determination of plant performance indicators and inspection findings. It is expected that a concrete scheme and detailed regulatory techniques for embodiment of RIR system in Korea will be

Current experience with nuclear power plant simulators and analysers

International Nuclear Information System (INIS)

Drozd, A.

1998-01-01

Topics of a Specialist Meeting are presented on Simulators and Plant Analyzers: Current Issues in Nuclear Power Plant Simulation (Espoo, Finland). They dealt with the need for maintaining expertise, training and education, control rooms and operator support tools, simulators as tools for plant safety analysis. The major conclusions of the payers and the meeting are discussed. (R.P.)

Re-Framing Biotechnology Regulation.

Science.gov (United States)

Peck, Alison

Biotechnology is about to spill the banks of federal regulation. New genetic engineering techniques like CRISPR-Cas9 promise revolutionary breakthroughs in medicine, agriculture, and public health—but those techniques would not be regulated under the terms of the Coordinated Framework for Regulation of Biotechnology. This revolutionary moment in biotechnology offers an opportunity to correct the flaws in the framework, which was hastily patched together at the advent of the technology. The framework has never captured all relevant technologies, has never satisfied the public that risk is being effectively managed, and has never been accessible to small companies and publicly-funded labs that increasingly are positioned to make radical, life-saving innovations. This Article offers a proposal for new legislation that would reshape biotechnology regulation to better meet these goals. Key reforms include tying regulation to risk rather than technology category; consolidating agency review; capturing distinct regulatory expertise through inter-agency consultations; creating a clearinghouse to help guide applicants and disseminate information; setting up more comprehensive monitoring of environmental effects; and providing federal leadership to fill key data gaps and address socio-economic impacts.

Present status of yellow fever: Memorandum from a PAHO Meeting

OpenAIRE

1986-01-01

An international seminar on the treatment and laboratory diagnosis of yellow fever, sponsored by the Pan American Health Organization (PAHO) and held in 1984, differed from previous meetings on yellow fever because of its emphasis on the care and management of patients and because the participants included specialists from several branches of medicine, such as hepatology, haematology, cardiology, infectious diseases, pathology and nephrology. The meeting reviewed the current status of yellow ...

40 CFR 152.6 - Substances excluded from regulation by FIFRA.

Science.gov (United States)

2010-07-01

... utilization of applied nitrogen. (ii) Reduces leaching of applied nitrogen or reduces groundwater nitrogen... from FIFRA regulation if they meet the specified conditions or criteria. (a) Liquid chemical sterilants...

Current problems of marine pollution. Papers

International Nuclear Information System (INIS)

Dethlefsen, V.

1993-01-01

During the lecture meeting of the working committee for waste water problems of the German Fishery Association, papers were presented on current problems of waste pollution and on the potential effects of climate changes on the fishing industry. (EF) [de

Regulations for the Safe Transport of Radioactive Materials. 1964 Revised Edition

International Nuclear Information System (INIS)

1965-01-01

In 1961 the International Atomic Energy Agency, within the framework of its statutory functions and in accordance with recommendations made by its Preparatory Commission and by the Economic and Social Council of the United Nations, published safety regulations which could be applied to the national and international transport of radio active materials by all means of transport. At the same time, the Director General of the Agency indicated that these regulations would be revised at appropriate intervals in consultation with Member States and the organizations concerned and invited suggestions for their improvement in the light of experience and increased knowledge. In preparing the revised regulations presented in this document, the Agency has received considerable support from its Member States and the organizations concerned, which have made extensive studies and suggestions in order to assist in its work. The Agency also convened several meetings of experts from its Member States and of representatives of a number of international organizations, and has been represented in several meetings convened by those organizations. In publishing the revised transport regulations which result from that co-ordinated effort, the Agency aims at proposing a lasting framework of principles and rules, complemented by appropriate technical data, acceptable for the safe transport of radio active materials by air, land and water. In particular, the developments which have been introduced concerning the packaging requirements, the nuclear safety criteria for the transport of fissile materials and the methods for testing packages should facilitate the international acceptance of packages by the authorities concerned. The Board of Governors of the Agency approved the revised regulations in June and September 1964. It authorized the Director General to apply them, as appropriate, to Agency operations and Agency assisted operations and to recommend to Member States and to the

Tenth LAMPF users meeting, November 7--9, 1976

International Nuclear Information System (INIS)

Rosen, L.

1977-03-01

The text of a brief talk given before the Tenth LAMPF Users Meeting is presented. Progress made at the Clinton P. Anderson Meson Physics Facility is reported, and the schedule for current upgrading and typical operating cost increases are given

76 FR 70709 - Sunshine Act Meeting; Emergency Meeting Notice

Science.gov (United States)

2011-11-15

... COMMODITY FUTURES TRADING COMMISSION Sunshine Act Meeting; Emergency Meeting Notice This notice that an emergency meeting was held is published pursuant to the provisions of the Government in the Sunshine Act, Public Law 94-409, 5 U.S.C. 552b. AGENCY HOLDING THE MEETING: Commodity Futures Trading...

Defining, Measuring, and Incentivizing Sustainable Land Use to Meet Human Needs

Science.gov (United States)

Nicholas, K. A.; Brady, M. V.; Olin, S.; Ekroos, J.; Hall, M.; Seaquist, J. W.; Lehsten, V.; Smith, H.

2016-12-01

Land is a natural capital that supports the flow of an enormous amount of ecosystem services critical to human welfare. Sustainable land use, which we define as land use that meets both current and future human needs for ecosystem services, is essential to meet global goals for climate mitigation and sustainable development, while maintaining natural capital. However, it is not clear what governance is needed to achieve sustainable land use under multiple goals (as defined by the values of relevant decision-makers and land managers), particularly under climate change. Here we develop a conceptual model for examining the interactions and tradeoffs among multiple goals, as well as their spatial interactions (teleconnections), in research developed using Design Thinking principles. We have selected five metrics for provisioning (food production, and fiber production for wood and energy), regulating and maintenance (climate mitigation and biodiversity conservation), and cultural (heritage) ecosystem services. Using the case of Sweden, we estimate indicators for these metrics using a combination of existing data synthesis and process-based simulation modeling. We also develop and analyze new indicators (e.g., combining data on land use, bird conservation status, and habitat specificity to make a predictive model of bird diversity changes on agricultural or forested land). Our results highlight both expected tradeoffs (e.g., between food production and biodiversity conservation) as well as unexpected opportunities for synergies under different land management scenarios and strategies. Our model also provides a practical way to make decision-maker values explicit by comparing both quantity and preferences for bundles of ecosystem services under various scenarios. We hope our model will help in considering competing interests and shaping economic incentives and governance structures to meet national targets in support of global goals for sustainable management of land

30 CFR 77.801-1 - Grounding resistors; continuous current rating.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Grounding resistors; continuous current rating... OF UNDERGROUND COAL MINES Surface High-Voltage Distribution § 77.801-1 Grounding resistors; continuous current rating. The ground fault current rating of grounding resistors shall meet the “extended...

30 CFR 77.901-1 - Grounding resistor; continuous current rating.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Grounding resistor; continuous current rating. 77.901-1 Section 77.901-1 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF... resistor; continuous current rating. The ground fault current rating of grounding resistors shall meet the...

Reducing Ripple In A Switching Voltage Regulator

Science.gov (United States)

Paulkovich, John; Rodriguez, G. Ernest

1994-01-01

Ripple voltage in output of switching voltage regulator reduced substantially by simple additional circuitry adding little to overall weight and size of regulator. Heretofore, additional filtering circuitry needed to obtain comparable reductions in ripple typically as large and heavy as original regulator. Current opposing ripple current injected into filter capacitor.

48{sup th} Annual meeting on nuclear technology (AMNT). Key topic / Outstanding know-how and sustainable innovations

Energy Technology Data Exchange (ETDEWEB)

Raetzke, Christian [CONLAR - Consulting on Nuclear Law, Licensing and Regulation, Leipzig (Germany)

2017-08-15

Summary report on the Key Topic Outstanding Know-How and Sustainable Innovations, Focus Session: International Regulation: Leveraging the Experience of Established Nuclear Countries for Regulations and Projects in Newcomer Countries, of the 48th Annual Meeting on Nuclear Technology (AMNT 2017) held in Berlin, 16 to 17 May 2017.

Meeting review: 2002 O'Reilly Bioinformatics Technology Conference.

Science.gov (United States)

Counsell, Damian

2002-01-01

At the end of January I travelled to the States to speak at and attend the first O'Reilly Bioinformatics Technology Conference. It was a large, well-organized and diverse meeting with an interesting history. Although the meeting was not a typical academic conference, its style will, I am sure, become more typical of meetings in both biological and computational sciences.Speakers at the event included prominent bioinformatics researchers such as Ewan Birney, Terry Gaasterland and Lincoln Stein; authors and leaders in the open source programming community like Damian Conway and Nat Torkington; and representatives from several publishing companies including the Nature Publishing Group, Current Science Group and the President of O'Reilly himself, Tim O'Reilly. There were presentations, tutorials, debates, quizzes and even a 'jam session' for musical bioinformaticists.

From cell regulation to patient survival: 2nd Cancer immunotherapy and immunomonitoring (CITIM) meeting, Budapest, 2–5 May 2011

Science.gov (United States)

Malyguine, Anatoli; Kotlan, Beatrix; Aptsiauri, Natalia; Shurin, Michael R.

2012-01-01

The 2nd International Conference “Cancer Immunotherapy and Immunomonitoring (CITIM)” took place in Budapest, Hungary, and was organized by the International (Chair—Michael Shurin) and Local (Chair—Beatrix Kotlan) Organizing Committees. The main aim was to bring the world’s best tumor immunologists to Budapest to discuss the mechanisms of immune regulation in the tumor microenvironment, the efficacy of anticancer immunotherapeutic modalities, the results of clinical trials and the methods of patients’ immunomonitoring. This report provides a short overview of novel concepts, strategies and clinical achievements in this quickly developing field of oncology since the first CITIM meeting held in Kiev, Ukraine, in 2009. Almost 200 participants from more than 30 countries of Europe, Asia, Africa, North and South America as well as from Australia were attracted by the scientific program that consisted of presentations from 58 international experts. Good memories remain from the lively discussions of ten plenary sessions, four Keynote lectures, two special plenary presentations, best abstract award session and 75 posters. PMID:22065047

Regulação de Concessão de Rodovias e o Papel do Estado / Road Concession Regulation and the Role of State

Directory of Open Access Journals (Sweden)

Laís Kimie Oshiro Caldeira

2016-05-01

Full Text Available Purpose – This paper seeks to establish standards for the assessment of regulation applied to highway concessions to comply with the state’s role as insurer of the public interest. Methodology/approach/design – The methodology consisted of a literature review on the theory of regulation, applying them to the sector of road concessions and performing an evaluation of the form of state intervention and the fulfillment of its objectives. Findings – The result was the identification of standards to be followed by regulation for that allows the qualification of the state’s role in highway concessions in Brazil and the fulfillment of its objectives. Originality/value – This paper analyzes systemically the application of regulation in the road sector that has very specific market characteristics allowing an evaluation of the quality and effectiveness of regulation in meeting the state’s role. The results are useful and innovative for a critical evaluation of the current regulation in Brazil and its evolution, both for scholars in the field, and for specialists working in the regulatory agencies of the transport sector.

Seasonality directs contrasting food collection behavior and nutrient regulation strategies in ants.

Science.gov (United States)

Cook, Steven C; Eubanks, Micky D; Gold, Roger E; Behmer, Spencer T

2011-01-01

Long-lived animals, including social insects, often display seasonal shifts in foraging behavior. Foraging is ultimately a nutrient consumption exercise, but the effect of seasonality per se on changes in foraging behavior, particularly as it relates to nutrient regulation, is poorly understood. Here, we show that field-collected fire ant colonies, returned to the laboratory and maintained under identical photoperiod, temperature, and humidity regimes, and presented with experimental foods that had different protein (p) to carbohydrate (c) ratios, practice summer- and fall-specific foraging behaviors with respect to protein-carbohydrate regulation. Summer colonies increased the amount of food collected as the p:c ratio of their food became increasingly imbalanced, but fall colonies collected similar amounts of food regardless of the p:c ratio of their food. Choice experiments revealed that feeding was non-random, and that both fall and summer ants preferred carbohydrate-biased food. However, ants rarely ate all the food they collected, and their cached or discarded food always contained little carbohydrate relative to protein. From a nutrient regulation strategy, ants consumed most of the carbohydrate they collected, but regulated protein consumption to a similar level, regardless of season. We suggest that varied seasonal food collection behaviors and nutrient regulation strategies may be an adaptation that allows long-lived animals to meet current and future nutrient demands when nutrient-rich foods are abundant (e.g. spring and summer), and to conserve energy and be metabolically more efficient when nutritionally balanced foods are less abundant.

Dancing with Hormones: A Current Perspective of Nitrate Signaling and Regulation in Arabidopsis

Directory of Open Access Journals (Sweden)

Peizhu Guan

2017-09-01

Full Text Available In nature and agriculture, nitrate availability is a main environmental cue for plant growth, development and stress responses. Nitrate signaling and regulation are hence at the center of communications between plant intrinsic programs and the environment. It is also well known that endogenous phytohormones play numerous critical roles in integrating extrinsic cues and intrinsic responses, regulating and refining almost all aspects of plant growth, development and stress responses. Therefore, interaction between nitrate and phytohormones, such as auxins, cytokinins, abscisic acid, gibberellins, and ethylene, is prevalent. The growing evidence indicates that biosynthesis, de-conjugation, transport, and signaling of hormones are partly controlled by nitrate signaling. Recent advances with nitrate signaling and transcriptional regulation in Arabidopsis give rise to new paradigms. Given the comprehensive nitrate transport, sensing, signaling and regulations at the level of the cell and organism, nitrate itself is a local and long-distance signal molecule, conveying N status at the whole-plant level. A direct molecular link between nitrate signaling and cell cycle progression was revealed with TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR1-20 (TCP20 – NIN-LIKE PROTEIN 6/7 (NLP6/7 regulatory nexus. NLPs are key regulators of nitrogen responses in plants. TCPs function as the main regulators of plant morphology and architecture, with the emerging role as integrators of plant developmental responses to the environment. By analogy with auxin being proposed as a plant morphogen, nitrate may be an environmental morphogen. The morphogen-gradient-dependent and cell-autonomous mechanisms of nitrate signaling and regulation are an integral part of cell growth and cell identification. This is especially true in root meristem growth that is regulated by intertwined nitrate, phytohormones, and glucose-TOR signaling pathways. Furthermore, the nitrate

Presentations at NuPECC meeting

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-07-01

The Nuclear Physics European Collaboration Committee (NuPECC) is an associated committee of the European Science Foundation. The objective of NuPECC is to strengthen European collaboration in nuclear sciences. In pursuing this objective the committee shall first define a network of complementary facilities within Europe and encourage optimization of their usage and secondly provide a forum for the discussion of future facilities and instrumentation. The first part of this NuPECC meeting was dedicated to the presentation of the main activities of the CENBG (Center for nuclear research of Bordeaux Gradignan), while the second part was devoted to reporting the status of current European collaborations (ECT{sup *}, ECOS, FP7, EURISOL and SPIRAL-2), a survey of operating small scale facilities in Europe is given. This document gathers only the slides presented at this meeting. (A.C.)

Presentations at NuPECC meeting

International Nuclear Information System (INIS)

2006-01-01

The Nuclear Physics European Collaboration Committee (NuPECC) is an associated committee of the European Science Foundation. The objective of NuPECC is to strengthen European collaboration in nuclear sciences. In pursuing this objective the committee shall first define a network of complementary facilities within Europe and encourage optimization of their usage and secondly provide a forum for the discussion of future facilities and instrumentation. The first part of this NuPECC meeting was dedicated to the presentation of the main activities of the CENBG (Center for nuclear research of Bordeaux Gradignan), while the second part was devoted to reporting the status of current European collaborations (ECT * , ECOS, FP7, EURISOL and SPIRAL-2), a survey of operating small scale facilities in Europe is given. This document gathers only the slides presented at this meeting. (A.C.)

The neuroendocrine regulation of food intake in fish: a review of current knowledge

Directory of Open Access Journals (Sweden)

Helene Volkoff

2016-11-01

Full Text Available Fish are the most diversified group of vertebrates and, although progress has been made in the past years, only relatively few fish species have been examined to date, with regards to the endocrine regulation of feeding in fish. In fish, as in mammals, feeding behavior is ultimately regulated by central effectors within feeding centers of the brain, which receive and process information from endocrine signals from both brain and peripheral tissues. Although basic endocrine mechanisms regulating feeding appear to be conserved among vertebrates, major physiological differences between fish and mammals and the diversity of fish, in particular in regard to feeding habits, digestive tract anatomy and physiology, suggest the existence of fish- and species-specific regulating mechanisms. This review provides an overview of hormones known to regulate food intake in fish, emphasizing on major hormones and the main fish groups studied to date.

13th annual meeting of the ALS Users' Association

International Nuclear Information System (INIS)

Robinson, Art

2000-01-01

A complement of 266 users, staff, and vendors descended upon the Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) from Monday through Wednesday, October 16-18, 2000 for the thirteenth edition of the annual Advanced Light Source (ALS) users meeting. In a departure from previous practice, the meeting featured an increased emphasis on workshops with the result that the proceedings were equally divided between oral and poster presentations and the workshops. After the traditional welcomes and facility updates on the first morning, science dominated the first day and a half comprising the formal meeting with a session of highlights from young researchers, three sessions of scientific highlights from the ALS and elsewhere, and a poster session that included a student poster competition. A set of seven workshops covering research areas of current or growing interest at the ALS rounded out the final day and a half of the meeting

A Robust Suboptimal Current Control of an Interlink Converter for a Hybrid AC/DC Microgrid

Directory of Open Access Journals (Sweden)

Ismi Rosyiana Fitri

2018-05-01

Full Text Available A hybrid AC/DC microgrid is established with the aim of exploiting numerous types of renewable energy to meet the needs of different loads. The microgrid is decomposed by AC DC sub-grids which are connected by an interlink converter (IC. To maintain the security and reliability of the microgrid, an automatic controller for the interlink converter is needed. In this paper, we propose a Linear Matrix Inequalities (LMI-based current control method for the interlink converter. As the main features here, the interlink converter permits bidirectional power exchange between both sub-grids when a power–demand imbalance occurs in one sub-grid regardless of the converter system parameters. Simulations with various filter parameters are performed using the Matlab/Simulink software to validate the effectiveness of the proposed controller. In comparison with the existing Linear Quadratic Regulator (LQR-based current control, the proposed method is more robust against unknown system parameters and high load perturbation.

Effects of the updated national emission regulation in China on circulating fluidized bed boilers and the solutions to meet them.

Science.gov (United States)

Li, Jingji; Yang, Hairui; Wu, Yuxin; Lv, Junfu; Yue, Guangxi

2013-06-18

The advantage of circulating fluidized bed (CFB) boilers in China is their ability to utilize low rank coal with low cost emission control. However, the new National Emission Regulation (NER) issued in early 2012 brings much more stringent challenges on the CFB industries, which also causes much attention from other countries. Based on the principle of a CFB boiler and previous operating experience, it is possible for the CFB boilers to meet the new NER and maintain the advantage of low cost emission control, while, more influences should be considered in their design and operation. To meet the requirement of the new NER, the fly ash collector should adopt a bag house or combination of electrostatic precipitator and bag filter to ensure dust emissions of less than 30 mg · Nm(-3). For SO2 emission control, the bed temperature should be strictly lower than 900 °C to maintain high reactivity and pores. The limestone particle size distribution should be ranged within a special scope to optimize the residence time and gas-solid reaction. At the same time, the injecting point should be optimized to ensure fast contact of lime with oxygen. In such conditions, the desulfurization efficiency could be increased more than 90%. For lower sulfur content fuels (emissions lower than that of the new NER, 100 mg · Nm(-3). For fuels with sulfur content higher than 1.5%, some simplified systems for flue gas desulfurization, such as flash dryer absorber (FDA), are needed. And the NOx emissions of a CFB can be controlled to less than 100 mg · Nm(-3) without any equipment at a bed temperature lower than 900 °C for fuels with low volatiles content (emission of CFB is very low for the new NER due to its innate property.

The international radioactive transportation regulations: A model for national regulations

International Nuclear Information System (INIS)

Pope, R.B.; Rawl, R.R.

1990-06-01

The International Atomic Energy Agency's (IAEA) Regulations for the Safe Transport of Radioactive Material, Safety Series No. 6 (herein after denoted as the ''International Regulations'') serve as the model for the regulations for individual countries and international modal organizations controlling the packaging and transportation of radioactive materials. The purpose of this paper is to outline the background and history of the International Regulations, the general principles behind the requirements of the International Regulations, the structure and general contents of the latest edition of the International Regulations, and the roles of various international bodies in the development and implementation of the International Regulations and the current status of regulatory and supportive document development at both the international and domestic level. This review will provide a basis for users and potential users to better understand the source and application of the International Regulations. 1 tab

Direct interaction of CaVβ with actin up-regulates L-type calcium currents in HL-1 cardiomyocytes.

Science.gov (United States)

Stölting, Gabriel; de Oliveira, Regina Campos; Guzman, Raul E; Miranda-Laferte, Erick; Conrad, Rachel; Jordan, Nadine; Schmidt, Silke; Hendriks, Johnny; Gensch, Thomas; Hidalgo, Patricia

2015-02-20

Expression of the β-subunit (CaVβ) is required for normal function of cardiac L-type calcium channels, and its up-regulation is associated with heart failure. CaVβ binds to the α1 pore-forming subunit of L-type channels and augments calcium current density by facilitating channel opening and increasing the number of channels in the plasma membrane, by a poorly understood mechanism. Actin, a key component of the intracellular trafficking machinery, interacts with Src homology 3 domains in different proteins. Although CaVβ encompasses a highly conserved Src homology 3 domain, association with actin has not yet been explored. Here, using co-sedimentation assays and FRET experiments, we uncover a direct interaction between CaVβ and actin filaments. Consistently, single-molecule localization analysis reveals streaklike structures composed by CaVβ2 that distribute over several micrometers along actin filaments in HL-1 cardiomyocytes. Overexpression of CaVβ2-N3 in HL-1 cells induces an increase in L-type current without altering voltage-dependent activation, thus reflecting an increased number of channels in the plasma membrane. CaVβ mediated L-type up-regulation, and CaVβ-actin association is prevented by disruption of the actin cytoskeleton with cytochalasin D. Our study reveals for the first time an interacting partner of CaVβ that is directly involved in vesicular trafficking. We propose a model in which CaVβ promotes anterograde trafficking of the L-type channels by anchoring them to actin filaments in their itinerary to the plasma membrane. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

Accessibility Guidelines for Astronomy and Astrophysics Meetings

Science.gov (United States)

Monkiewicz, Jacqueline; Murphy, Nicholas; Diaz-Merced, Wanda Liz; Aarnio, Alicia; Knierman, Karen; AAS Working Group for Accessibility and Disability

2018-01-01

Attendance at meetings and conferences is a critical component of an astronomer's professional life, providing opportunities for presenting one's work, staying current in the field, career networking, and scientific collaboration. Exclusion from these gatherings due to lack of accessibility and accommodation failure is a reality for disabled astronomers, and contributes substantially to low levels of representation in the senior-most levels of the field. We present a preview of the AAS Working Group for Accessibility and Disability's best practice recommendations for meetings accessibility. Applying the principles of universal access and barrier-free design, we model a paradigm of anticipating and removing accessibility barriers in advance, rather than putting the burden of requesting accommodation solely on disabled astronomers and students. We cite several professional and nonprofessional societies identified as meetings accessibility exemplars, and model our guidelines on their best practices. We establish standards for accessibility budgeting, venue choice, publication of policies online, designating point persons, and identifying barriers. We make recommendations for oral and poster presentations, event registration, receptions and banquets, excursions, and other typical conference activities. For meetings which are constrained by fixed budgets and venue choice, we identify a number of low cost/high reward accessibility steps which might still have a large beneficial impact. We likewise provide adapted recommendations for low budget meetings. THIS IS A POSTER LOCATED IN THE AAS BOOTH

33 CFR 96.230 - What objectives must a safety management system meet?

Science.gov (United States)

2010-07-01

... management system meet? 96.230 Section 96.230 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY VESSEL OPERATING REGULATIONS RULES FOR THE SAFE OPERATION OF VESSELS AND SAFETY MANAGEMENT SYSTEMS Company and Vessel Safety Management Systems § 96.230 What objectives must a safety...

Meals at medical specialty society annual meetings: a preliminary assessment.

Science.gov (United States)

La Puma, John; Schiedermayer, David; Becker, Jennifer

2003-01-01

Little isd known about how meals are chosen for medical meetings. We surveyed the annual meeting planners for 20 major specialty societies. Thirteen (65%) responded; all were currently planning their next meeting. Attendance in 2000 was reported at 113,477 physicians, with 2 million planned meals and snacks. No physician was named as responsible for food choices; the meeting planner and staff were primarily responsible for deciding what food to serve, excluding exhibit halls. Twelve (92%) respondents rated "available budget" as the most important factor. "Nutritional guidelines" were rated "very important" by eight of 13 (63%). However, no specific nutritional guidelines could be identified by any planner. All respondents indicated that members would attend a meeting if "healthy" food were the only option. For 2000, 100% of respondents indicated that for each lunch and for each dinner, a dessert had been included. No annual meeting and no planned 2001 meeting excluded potato chips, snack mixes, or candies at breaks; soda pop was offered at each break. Most respondents (89%) relied on a concluding questionnaire about the meeting facilities to evaluate the food. Respondents reported no difference in charges for "special meals," including vegetarian and kosher meals. Physicians may be unaware that some food served at medical meetings may impair learning, with excessive calorie, fat, and carbohydrate consumption. Small changes can improve the quality of food and beverages selected, without increased cost, and provide choices that conform to national nutritional guidelines. Medical meetings should serve flavorful, healthful food.

Eight meeting of the ITER diagnostic expert group

International Nuclear Information System (INIS)

Costley, A.E.; Young, K.M.

1998-01-01

The 8. Meeting of the ITER Diagnostics Expert Group which was held in San Diego, February 1998 had two main technical goals: to discuss the status and plans for developing kinetic control, and to review the current status of the design of the magnetic system

Original : English STANDING CONCERTATION COMMITTEE ORDINARY MEETING ON 28 MARCH 2001

CERN Multimedia

2001-01-01

This meeting was mainly devoted to follow-up from the Finance Committee in March, to preparation for TREF in May and to discussion of status reports from several Sub-Groups of the SCC. 1. Follow-up from the meeting of the Finance Committee in March and preparation for the meeting of TREF in May As agreed at the Finance Committee in March, the Management will prepare an explanatory document on the discrepancy of -0.3% in the net salary adjustment applied as a result of the 5-yearly Review. This document will be presented at the next meeting of TREF on 18 May, and then to the Finance Committee on 13 June. Other items on TREF's Draft Agenda include a status report on preparation for implementing the new career structure in September, together with modifications of the Staff Rules and Regulations, and a status report on implementation of detailed provisions concerning Long-Term Care. The Staff Association suggested that the subject of staffing levels should also be included in the agenda for TREF. The Management ...

BCI meeting 2005--workshop on technology: hardware and software.

Science.gov (United States)

Cincotti, Febo; Bianchi, Luigi; Birch, Gary; Guger, Christoph; Mellinger, Jürgen; Scherer, Reinhold; Schmidt, Robert N; Yáñez Suárez, Oscar; Schalk, Gerwin

2006-06-01

This paper describes the outcome of discussions held during the Third International BCI Meeting at a workshop to review and evaluate the current state of BCI-related hardware and software. Technical requirements and current technologies, standardization procedures and future trends are covered. The main conclusion was recognition of the need to focus technical requirements on the users' needs and the need for consistent standards in BCI research.

Symposium on Current Research in the Chemical Sciences: Third Annual Southern Station Chemical Sciences Meeting

Science.gov (United States)

Timothy G. Rials; [Editor

1994-01-01

The original charter for this annual meeting of chemical sciences personnel called for an informal atmosphere for the discussion of common concerns and needs. The years have seen the definition of our "common concern" evolve into a sharing of our efforts in applying the science of chemistry to the resolution of problems faced by our forest resource. I believe...

An assessment of the fire protection requirements throughout a NPP life related to current IAEA regulations and American, Canadian and UE regulations

International Nuclear Information System (INIS)

Branzeu, N.; Necula, D.; Badea, M.; Teodorescu, D.; Peteu, M.

2006-01-01

Statistics on fires has surprisingly shown that the frequency of fires in a nuclear power plant are as high as in the conventional industrial units. The analyses on fires occurred in a NPP need to consider both their well-known severe damages and the nuclear consequences. In 1975 a severe fire occurred in BROWNS FERRY NPP due to the ignition of the polyurethane foam used in the electric cable penetration sealings. The fire propagated to the cable channels and damaged over 1600 cables. The fire event revealed important shortcomings in the fire protection design and procedures. The fire represented a crucial event that changed fundamentally the fire protection regulation in the United States nuclear industry. The fire protection programs, standards and guides currently applied, have been developed on basis of this fire analysis and gained conclusions/experience. The purpose of the article is to be a short presentation of the fire protection requirements for all NPP life stages (i.e. design, construction, commissioning, operation and decommissioning), including the most recent issues of the standards, codes, guides and regulations in US, Canada, IAEA and some European countries. Such documentation represented the main technical support in establishing the national fire protection standard design regarding all the stages of a CANDU-6 NPP life, all the types of operational NPPs, particularly for Cernavoda NPP Unit 1 and Unit 2 (now in an advanced stage of construction). In order to satisfy the requirements provided by this documentation, as practically as possible, a list of analyses and fire protection improvement measures for Cernavoda NPP is presented. (authors)

Changes in Policy and Market and Network Regulation to Increase Power Generation by Renewables and DG in the EU

International Nuclear Information System (INIS)

Van Oostvoorn, F.; Van der Welle, A.

2009-01-01

Recently the importance of 'Large scale DER integration' has increased as means to meet the ambitious 2020 EU policy objectives and targets for RES, emissions reductions and energy efficiency. Increasing the role of RES and DG (Renewable Energy Sources and Distributed Generation or DER) in supply is also highly beneficial for reducing EU dependency on gas and oil imports. In this EU context, it is important to review the current barriers, support policies and network regulation for integration of more DG, RES and small scale CHP (Combined Heat and Power) in the power systems. Several studies conducted for the EU and led by the ECN (Energy research Centre of the Netherlands) reveal that currently, in some, mainly new, Member States, the contribution of RES and DG is still very low. However, in coming decades the share of variable RES-E sources should become much larger in many EU countries. Note that 20% RES in a country in 2020 implies a share of electricity supply by RES of about 30% or more. Currently, countries like Denmark and Spain, already experience such a large contribution of (mostly intermittent type) renewables and this is already negatively impacting power system costs. Now the question arises whether or not we can increase the contribution of RES to the power supply beyond 20-30% without raising system inefficiency and what changes in system conditions and market and network regulation are necessary to efficiently absorb large volumes of so called intermittent RES supply resources. Based on findings from several large EU projects promoting the role of RES and DG in the power supply, the authors discuss and present the different barriers and solutions that should facilitate meeting the ambitious EU policy targets for RES in 2020

Basally activated nonselective cation currents regulate the resting membrane potential in human and monkey colonic smooth muscle

Science.gov (United States)

Dwyer, Laura; Rhee, Poong-Lyul; Lowe, Vanessa; Zheng, Haifeng; Peri, Lauren; Ro, Seungil; Sanders, Kenton M.

2011-01-01

Resting membrane potential (RMP) plays an important role in determining the basal excitability of gastrointestinal smooth muscle. The RMP in colonic muscles is significantly less negative than the equilibrium potential of K+, suggesting that it is regulated not only by K+ conductances but by inward conductances such as Na+ and/or Ca2+. We investigated the contribution of nonselective cation channels (NSCC) to the RMP in human and monkey colonic smooth muscle cells (SMC) using voltage- and current-clamp techniques. Qualitative reverse transcriptase-polymerase chain reaction was performed to examine potential molecular candidates for these channels among the transient receptor potential (TRP) channel superfamily. Spontaneous transient inward currents and holding currents were recorded in human and monkey SMC. Replacement of extracellular Na+ with equimolar tetraethylammonium or Ca2+ with Mn2+ inhibited basally activated nonselective cation currents. Trivalent cations inhibited these channels. Under current clamp, replacement of extracellular Na+ with N-methyl-d-glucamine or addition of trivalent cations caused hyperpolarization. Three unitary conductances of NSCC were observed in human and monkey colonic SMC. Molecular candidates for basally active NSCC were TRPC1, C3, C4, C7, M2, M4, M6, M7, V1, and V2 in human and monkey SMC. Comparison of the biophysical properties of these TRP channels with basally active NSCC (bINSCC) suggests that TRPM4 and specific TRPC heteromultimer combinations may underlie the three single-channel conductances of bINSCC. In conclusion, these findings suggest that basally activated NSCC contribute to the RMP in human and monkey colonic SMC and therefore may play an important role in determining basal excitability of colonic smooth muscle. PMID:21566016

CSNI specialist meeting on leak-before-break in nuclear reactor piping: proceedings

Energy Technology Data Exchange (ETDEWEB)

1984-08-01

On September 1 and 2, 1983, the CSNI subcommittee on primary system integrity held a special meeting in Monterey, California, on the subject of leak-before-break in nuclear reactor piping systems. The purpose of the meeting was to provide an international forum for the exchange of ideas, positions, and research results; to identify areas requiring additional research and development; and to determine the general attitude toward acceptance of the leak-before-break concept. The importance of the leak-before-break issue was evidenced by excellent attendance at the meeting and through active participation by the meeting attendees. Approximately 125 people representing fifteen different nations attended the meeting. The meeting was divided into four technical sessions addressing the following areas: Application of Piping Fracture Mechanics to Leak-Before Break, Leak Rate and Leak Detection, Leak-Before-Break Studies, Methods and Results, Current and Proposed Positions on Leak-Before-Break.

CSNI specialist meeting on leak-before-break in nuclear reactor piping: proceedings

International Nuclear Information System (INIS)

1984-08-01

On September 1 and 2, 1983, the CSNI subcommittee on primary system integrity held a special meeting in Monterey, California, on the subject of leak-before-break in nuclear reactor piping systems. The purpose of the meeting was to provide an international forum for the exchange of ideas, positions, and research results; to identify areas requiring additional research and development; and to determine the general attitude toward acceptance of the leak-before-break concept. The importance of the leak-before-break issue was evidenced by excellent attendance at the meeting and through active participation by the meeting attendees. Approximately 125 people representing fifteen different nations attended the meeting. The meeting was divided into four technical sessions addressing the following areas: Application of Piping Fracture Mechanics to Leak-Before Break, Leak Rate and Leak Detection, Leak-Before-Break Studies, Methods and Results, Current and Proposed Positions on Leak-Before-Break

Nanomaterials: Regulation and Risk Assessment

DEFF Research Database (Denmark)

Hansen, Steffen Foss; Grieger, Khara Deanne; Baun, Anders

2013-01-01

, the Water Framework Directive, pharmaceuticals regulation, and the Novel Foods Regulation. Current regulation of nanomaterials entail three overall challenges: 1) limitations in regard to terminology and definitions of key terms such as a “substance,” “novel food,” etc.; 2) safety assessment requirements...

Remedial action programs annual meeting: Meeting notes

International Nuclear Information System (INIS)

1987-01-01

The US Department of Energy Grand Junction Projects Office was pleased to host the 1987 Remedial Action programs Annual Meeting and herein presents notes from that meeting as prepared (on relatively short notice) by participants. These notes are a summary of the information derived from the workshops, case studies, and ad hoc committee reports rather than formal proceedings. The order of the materials in this report follows the actual sequence of presentations during the annual meeting

Spring Meeting of the German Physical Society : Arbeitskreis FestkÖrperphysik

CERN Document Server

the German Physical Society : Arbeitskreis FestkÖrperphysik

1998-01-01

This volume contains the invited papers of the Spring meeting of the Arbeitskreis Festkörperphysik of the Deutsche Physikalische Gesellschaft, which has been held in Münster in 1997. The meeting has been attended by roughly 4000 participants from all areas of solid state physics. This book covers the current status of the fileds and shows the excitement which has been felt by the speakers when presenting their results.

To quell obesity, who should regulate food marketing to children?

Directory of Open Access Journals (Sweden)

Kelly Ben

2005-07-01

Full Text Available Abstract The global hegemony of the United States in the production and marketing of food, while a marvel of economic success, has contributed to the epidemic of obesity that is particularly afflicting children. So far the U.S. government has declined to regulate the aggressive ways in which food producers market high-energy, low-nutrition foods to young people. That public-health responsibility has been left to an industry-created scheme of self-regulation that is deeply flawed; there is a compelling need for government involvement. The issue is certain to be raised by health advocates at a U.S. Federal Trade Commission meeting in mid-July to discuss the self-regulatory approach, but the outlook for remedies to emerge from the meeting is not encouraging.

77 FR 48108 - Energy Conservation Standards for Commercial Clothes Washers: Public Meeting and Availability of...

Science.gov (United States)

2012-08-13

... commercial matters regulated by U.S. antitrust laws. After the public meeting and the expiration of the.... Code, for editorial reasons.) The Energy Policy Act of 2005 (EPACT 2005), Public Law 109-58, further...

Regulating danger on the highways: hours of service regulations.

Science.gov (United States)

Mansfield, Daniel; Kryger, Meir

2015-12-01

Current hours of service regulations governing commercial truck drivers in place in the United States, Canada, Australia, and the European Union are summarized and compared to facilitate the assessment of the effectiveness of such provisions in preventing fatigue and drowsiness among truck drivers. Current hours of service provisions governing commercial truck drivers were derived from governmental sources. The commercial truck driver hours of service provisions in the United States, Canada, and the European Union permit drivers to work 14 hours and those of Australia permit drivers to work 12 hours a day on a regular basis. The regulations do not state what a driver may do with time off. They are consistent with a driver being able to drive after 24 hours without sleep. They do not take into account circadian rhythm by linking driving or rest to time of day. Current hours of service regulations governing commercial truck drivers leave gaps--permitting drivers to work long hours on a regular basis, permitting driving after no sleep for 24 hours, and failing to take into account the importance of circadian rhythm, endangering the public safety and the truck drivers themselves. Copyright © 2015 National Sleep Foundation. Published by Elsevier Inc. All rights reserved.

Employment and First-Year College Achievement: The Role of Self-Regulation and Motivation

Science.gov (United States)

Huie, Faye C.; Winsler, Adam; Kitsantas, Anastasia

2014-01-01

Students often work in order to meet monetary requirements for college. However, employment reduces the time students can devote to their studies, which can hinder performance. This study examined whether motivation (self-efficacy goal orientation) and self-regulated learning (help-seeking, metacognitive self-regulation, time management and effort…

76 FR 59454 - Sunshine Act Meeting; Notice of Public Meeting

Science.gov (United States)

2011-09-26

... RAILROAD RETIREMENT BOARD Sunshine Act Meeting; Notice of Public Meeting Notice is hereby given that the Railroad Retirement Board will hold a meeting on October 6, 2011, 10 a.m. at the Board's meeting room on the 8th floor of its headquarters building, 844 North Rush Street, Chicago, Illinois...

12 CFR 225.83 - What are the consequences of failing to continue to meet applicable capital and management...

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 3 2010-01-01 2010-01-01 false What are the consequences of failing to continue to meet applicable capital and management requirements? 225.83 Section 225.83 Banks and Banking... AND CHANGE IN BANK CONTROL (REGULATION Y) Regulations Financial Holding Companies § 225.83 What are...

Current status of fusion-relevant covariance data

International Nuclear Information System (INIS)

Muir, D.W.

1994-01-01

The following review of the current status of formatted data covariance files and their multigroup processing is a contribution to the IAEA Advisory Group Meeting on ''Improved Evaluations and Integral Data Testing for FENDL,'' to be held at the Max-Planck-Institut fuer Plasmaphysik, Garching, Germany, 12--16 September 1994. The draft agenda of this meeting lists as Item 6 the ''assessment of present status and role of uncertainty files, their processing and sensitivity studies related to FENDL.'' We conclude that this is an important and timely topic and recommend needed actions in this field

33 CFR 96.240 - What functional requirements must a safety management system meet?

Science.gov (United States)

2010-07-01

... a safety management system meet? 96.240 Section 96.240 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY VESSEL OPERATING REGULATIONS RULES FOR THE SAFE OPERATION OF VESSELS AND SAFETY MANAGEMENT SYSTEMS Company and Vessel Safety Management Systems § 96.240 What functional...

Do the public think medical regulation keep them safe?

Science.gov (United States)

Yam, Carrie Ho-Kwan; Wong, Eliza Lai-Yi; Griffiths, Sian M; Yeoh, Eng-Kiong

2018-03-01

To assess public knowledge and expectations of the ways to assess doctors' competence to ensure patient safety. Telephone survey of a random sample of 1000 non-institutionalized Hong Kong residents. Only 5% of public were correct that doctors are not required to periodically be assessed, and 9% were correct that the doctors are not required to update knowledge and skills for renewing their license. These results echo international studies showing a low public knowledge of medical regulation. The public overwhelmingly felt a periodic assessment (92%) and requirements for continuous medical education (91%) were important processes for assuring doctors' competence. A high proportion of the public felt that lay representation in the Medical Council was insufficient. There is a significant gap between public expectations and understanding of the existing medical regulation and the actual policies and practices. Despite a lack of public knowledge, the public thought it important to have an ongoing structured monitoring and assessment mechanism to assure doctors' competence. The public also expects a greater involvement in the regulatory processes as members of the Medical Council. There is a need to review and enhance the current regulatory system to meet public expectation and ensure accountability for the privilege and trust granted by the State in professional self-regulation. In the context of our complex health system, a thorough understanding on the dynamic interactions between different institutions and their complementary roles in a meta-regulatory framework is required in assuring patient safety.

Towards spatially differentiated regulation of nitrogen

DEFF Research Database (Denmark)

Lajer Højberg, Anker; Refsgaard, Jens Christian; Jørgensen, Lisbeth Flindt

EU member states are challenged by nitrogen loads to estuaries and inland freshwater systems impeding the achievement of good ecological status as required by the Water Framework Directive (WFD). In Denmark nitrate leaching from the root zone has been reduced by 50% since 1987, but additional...... reductions of 30-50% are required to meet the objectives of the WFD. Achieving such abatements by uniform restrictions for all areas, would be very costly and inefficient as studies have shown that reduction varies spatially depending on the local hydrogeological conditions, the presence and dynamics...... of drains and hydro-biogeochemical conditions in associated riparian lowlands. Hence, a shift of paradigm in regulation practice is needed, whit a cost-effective regulation accounting for this variability and differentiate the regulations/restrictions between resilient and vulnerable areas. However...

Risk analysis of nuclear safeguards regulations

International Nuclear Information System (INIS)

Al-Ayat, R.A.; Altman, W.D.; Judd, B.R.

1982-06-01

The Aggregated Systems Model (ASM), a probabilisitic risk analysis tool for nuclear safeguards, was applied to determine benefits and costs of proposed amendments to NRC regulations governing nuclear material control and accounting systems. The objective of the amendments was to improve the ability to detect insiders attempting to steal large quantities of special nuclear material (SNM). Insider threats range from likely events with minor consequences to unlikely events with catastrophic consequences. Moreover, establishing safeguards regulations is complicated by uncertainties in threats, safeguards performance, and consequences, and by the subjective judgments and difficult trade-offs between risks and safeguards costs. The ASM systematically incorporates these factors in a comprehensive, analytical framework. The ASM was used to evaluate the effectiveness of current safeguards and to quantify the risk of SNM theft. Various modifications designed to meet the objectives of the proposed amendments to reduce that risk were analyzed. Safeguards effectiveness was judged in terms of the probability of detecting and preventing theft, the expected time to detection, and the expected quantity of SNM diverted in a year. Data were gathered in tours and interviews at NRC-licensed facilities. The assessment at each facility was begun by carefully selecting scenarios representing the range of potential insider threats. A team of analysts and facility managers assigned probabilities for detection and prevention events in each scenario. Using the ASM we computed the measures of system effectiveness and identified cost-effective safeguards modifications that met the objectives of the proposed amendments

French-speaking meeting on fuzzy logic and its applications

International Nuclear Information System (INIS)

1997-01-01

The 1997 edition of LFA'97 meeting for fuzzy logic has been organized by the Pattern Recognition and Computer Vision Laboratory of the National Institute of Applied Sciences. The objective of the meeting was to provide a forum for researchers and users of fuzzy logic and possibility theory to present and discuss theoretical researches and concrete applications. The domains in concern are: the control decision theory, the pattern recognition and image analysis, the artificial intelligence and the information systems. From the 41 papers of this book, two were selected for ETDE and deal with fuzzy regulation systems for heating systems and with fuzzy controllers for gas refining plants, and one was selected for INIS and deal with real-time surveillance and fuzzy logic control systems for nuclear power plants. (J.S.)

Exploring dialectical behaviour therapy clinicians' experiences of team consultation meetings.

Science.gov (United States)

Walsh, Cian; Ryan, Patrick; Flynn, Daniel

2018-01-01

This article presents a detailed idiographic analysis of Dialectical Behaviour Therapy (DBT) clinicians' experiences of team consultation meetings. DBT is an evidence-based psychological intervention with a demonstrated efficacy in the treatment of borderline personality disorder (BPD). Team consultation meetings encompass one of the primary components involved in this treatment model; where DBT clinicians regularly meet to discuss client work and enhance further learning. The present study's aim was to assess what are DBT clinicians' experiences of the consultation meeting component and whether it is useful or not. Semi-structured interviews were completed with 11 DBT clinicians (nine females, two males) from three different consultation teams. The research project utilised an interpretative phenomenological analysis (IPA) framework. Audio-recorded interview data was analysed using this framework. Four superordinate themes emerged from the interview data, which included ten subordinate themes. The superordinate themes focused on: (1) the acquisition of DBT technical knowledge and other MDT related expertise (2) participants' emotional experiences of DBT and consultation meetings, and how this can evolve over time (3) the underlying processes that occur in the consultation team including the development of a team bond and the impact of membership changes and (4) the largely consistent and reliable nature of consultation meetings and how they help maintain clinician motivation. Team consultation meetings were found to be supportive; playing an important role in maintaining clinician motivation through the availability of team support, opportunities to reflect and learn, and assistance in regulating emotions. Challenges arose in relation to team membership changes and acclimatisation to the type of feedback utilised in team consultation. The study's implications for practise are considered.

18th informal meeting on reactor noise

International Nuclear Information System (INIS)

Dach, K.

1986-01-01

The proceedings contain the texts of 24 papers all of which fall under the INIS Subject Scope. The main purpose of the meeting of more than 90 scientists and specialists from 18 countries was for them to get acquainted with the current state and prospective development of noise diagnostics application in nuclear reactor operation. (Z.M.)

75 FR 61819 - National Emergency Medical Services Advisory Council (NEMSAC); Teleconference Meeting

Science.gov (United States)

2010-10-06

... Document Management System (DMS) at http://www.regulations.gov/ under the docket number listed at the beginning of this notice. The DMS is available 24 hours each day, 365 days each year. Electronic submission... NEMSAC Meeting will be available to the public online through the DOT Document Management System (DMS) at...

Combined heat and power's potential to meet New York City's sustainability goals

International Nuclear Information System (INIS)

Howard, Bianca; Saba, Alexis; Gerrard, Michael; Modi, Vijay

2014-01-01

Combined Heat and Power (CHP) has been proven as a mature technology that can benefit both building owners and utility operators. As the economic and environmental benefits of CHP in urban centers gain recognition, regulations and policies have evolved to encourage their deployment. However, the question remains whether these policies are sufficient in helping to achieve the larger sustainability goals, such as the New York City-specific goal of incorporating 800 MW of distributed generation. In this paper, the current regulatory and policy environment for CHP is discussed. Then, an engineering analysis estimating the potential for CHP in NYC at the individual building and microgrid scale, considered a city block, is performed. This analysis indicates that over 800 MW of individual building CHP systems would qualify for the current incentives but many systems would need to undergo more cumbersome air permitting processes reducing the viable capacity to 360 MW. In addition microgrid CHP systems with multiple owners could contribute to meeting the goal even after considering air permits; however, these systems may incorporate many residential customers. The regulatory framework for microgrids with multiple owners and especially residential customers is particularly uncertain therefore additional policies would be needed to facilitate their development. - Highlights: • Estimates 1580 MW and 3042 MW CHP capacity at the building and microgrid scales. • Citywide emissions could reduce 4% at the building and 9% at the microgrid scale. • CHP microgrid systems operate at similar efficiencies while providing energy to buildings not viable for CHP. • Current regulatory and policy mechanisms would affect at least 800 MW of CHP systems. • Microgrid CHP systems may be necessary to the City's meet distributed generation goals

Regulation of fertilization and early seed development.

Science.gov (United States)

Dresselhaus, Thomas; Doughty, James

2014-04-01

Plant reproduction meetings often deal either with pre-fertilization processes such as flowering and pollen biology or post-fertilization processes such as embryogenesis and seed development. The Biochemical Society Focused Meeting entitled 'Regulation of Fertilization and Early Seed Development' was organized to close this gap and to discuss mechanistic similarities and future research directions in the reproductive processes shortly before, during and after fertilization. As an outcome of the workshop, invited speakers and a few selected oral communication presenters contributed focused reviews and technical articles for this issue of Biochemical Society Transactions. We provide here a short overview of the contents and highlights of the various articles.

Control assembly materials for water reactors: Experience, performance and perspectives. Proceedings of a technical committee meeting

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-02-01

The safe, reliable and economic operation of water cooled nuclear power reactors depends to a large extent upon the reliable operation of control assemblies for the regulation and shutdown of the reactors. These consist of neutron absorbing materials clad in stainless steel or zirconium based alloys, guide tubes and guide cards, and other structural components. Current designs have worked extremely well in normal conditions, but less than ideal behaviour limits the lifetimes of control materials, imposing an economic penalty which acts as a strong incentive to produce improved materials and designs that are more reliable. Neutron absorbing materials currently in use include the ceramic boron carbide, the high melting point metal hafnium and the low melting point complex alloy Ag-In-Cd. Other promising neutron absorbing materials, such as dysprosium titanate, are being evaluated in the Russian Federation. These control materials exhibit widely differing mechanical, physical and chemical properties, which must be understood in order to be able to predict the behaviour of control rod assemblies. Identification of existing failure mechanisms, end of life criteria and the implications of the gradual introduction of extended burnup, mixed oxide (MOX) fuels and more complex fuel cycles constitutes the first step in a search for improved materials and designs. In the early part of this decade, it was recognized by the International Working Group on Fuel Performance and Technology (IWGFPT) that international conferences, symposia and published reviews on the materials science aspects of control assemblies were few and far between. Consequently, the IWGFPT recommended that the IAEA should rectify this situation with a series of Technical Committee meetings (TCMs) devoted entirely to the materials aspects of reactor control assemblies. The first was held in 1993 and in the intervening five years considerable progress has been made. In bringing together experts in the

Control assembly materials for water reactors: Experience, performance and perspectives. Proceedings of a technical committee meeting

International Nuclear Information System (INIS)

2000-02-01

The safe, reliable and economic operation of water cooled nuclear power reactors depends to a large extent upon the reliable operation of control assemblies for the regulation and shutdown of the reactors. These consist of neutron absorbing materials clad in stainless steel or zirconium based alloys, guide tubes and guide cards, and other structural components. Current designs have worked extremely well in normal conditions, but less than ideal behaviour limits the lifetimes of control materials, imposing an economic penalty which acts as a strong incentive to produce improved materials and designs that are more reliable. Neutron absorbing materials currently in use include the ceramic boron carbide, the high melting point metal hafnium and the low melting point complex alloy Ag-In-Cd. Other promising neutron absorbing materials, such as dysprosium titanate, are being evaluated in the Russian Federation. These control materials exhibit widely differing mechanical, physical and chemical properties, which must be understood in order to be able to predict the behaviour of control rod assemblies. Identification of existing failure mechanisms, end of life criteria and the implications of the gradual introduction of extended burnup, mixed oxide (MOX) fuels and more complex fuel cycles constitutes the first step in a search for improved materials and designs. In the early part of this decade, it was recognized by the International Working Group on Fuel Performance and Technology (IWGFPT) that international conferences, symposia and published reviews on the materials science aspects of control assemblies were few and far between. Consequently, the IWGFPT recommended that the IAEA should rectify this situation with a series of Technical Committee meetings (TCMs) devoted entirely to the materials aspects of reactor control assemblies. The first was held in 1993 and in the intervening five years considerable progress has been made. In bringing together experts in the

Current algebra for parafields

International Nuclear Information System (INIS)

Palev, Ch.D.

1976-01-01

Within the framework of the Lagrangean QFT a generalization of canonical commutation and anticommutation relations in terms of three-linear commutation relations, corresponding to the parastatistics, s discussed. A detailed derivation of these three-linear relations for a set of parafermi fields is presented. Then for a Lagrangean, depending of a family of parabose fields and a family of paraferm fields, is shown that the fundamental hypothesis of current algebra is valid. In other words, the currents corresponding to the linear gauge transformations are found to meet the commutation relation: [Jsub(f)sup(0)(x), Jsub(g)sup(0)]sub(x 0 =y 0 ) = -idelta(x vector - y vector)Jsub([f,g])sup(0) (x), where Jsub(f)sup(0) is a time component of the current, corresponding to transformation f. (S.P.)

Report on the environmental safety evaluation sub-committee meetings in fiscal 1987; 1987 nendo kankyo anzensei hyoka bukai hokokusho

Energy Technology Data Exchange (ETDEWEB)

NONE

1988-03-01

The environmental safety evaluation sub-committee has held two meeting in the current fiscal year as described below. The first sub-committee meeting (August 25, 1987) was held for the agenda of the summary of future test plans, the result of overseas surveys in fiscal 1986, the results of tests in fiscal 1986, and the summary of the test plan for fiscal 1987. The major agendum of the second sub-committee meeting (February 23) was the interim reports on the overseas survey results and the safety tests in fiscal 1987. NEDO intends to ensure the labor hygiene for workers in coal liquefying plants, the effect of liquefied oil on users' health, and social acceptability of liquefied oil. Therefore, a safety test for liquefied oil in the primary hydrogenation process was performed provisionally on brown coal PP in the initial stage of operation, in addition to bituminous coal liquefied oil at the existing 1-t/d PDU. The main contents of the test performed by NEDO are based on the labor safety and hygiene law and the law related to regulation on the deliberation and manufacture of chemical materials. Different tests using guinea pigs were carried out on the total fraction mixed at the 1-t/d PDU, and each fraction of light and heavy oils, where the liquefied oil was verified to have minor degree of toxicity. (NEDO)

76 FR 59381 - Codex Alimentarius Commission: Meeting of the Codex Committee on Food Hygiene

Science.gov (United States)

2011-09-26

..._Subscription/ . Options range from recalls, export information, regulations, directives, and notices. Customers... November 15, 2011. The objective of the public meeting is to provide information and receive public... FDA recognize the importance of providing interested parties the opportunity to obtain background...

Mina: a Th2 response regulator meets TGFβ.

Science.gov (United States)

Pillai, Meenu R; Lian, Shangli; Bix, Mark

2014-12-01

The JmjC protein Mina is an important immune response regulator. Classical forward genetics first discovered its immune role in 2009 in connection with the development of T helper 2 (Th2) cells. This prompted investigation into Mina's role in the two best-studied contexts where Th2 responses are essential: atopic asthma and helminth expulsion. In work focused on a mouse model of atopic asthma, Mina deficiency was found to ameliorate airway hyper-resistance and pulmonary inflammation. And, in a case-control study genetic variation at the human MINA locus was found to be associated with the development of childhood atopic asthma. Although the underlying cellular and molecular mechanism of Mina's involvement in pulmonary inflammation remains unknown, our recent work on parasitic helminth expulsion suggests the possibility that, rather than T cells, epithelial cells responding to TGFβ may play the dominant role. Here we review the growing body of literature on the emerging Mina pathway in T cells and epithelial cells and attempt to set these into a broader context. Copyright © 2014 Elsevier Ltd. All rights reserved.

Reflexive regulation of CSR to promote sustainability

DEFF Research Database (Denmark)

Buhmann, Karin

2011-01-01

and the EU CSR Alliance. Focusing on human rights based in international law, it analyses the patterns of negotiation in the MSF and the background for the launch of the CSR Alliance. It shows that analysing public-private regulation of CSR from the perspective of reflexive law theory assists us......This article discusses Corporate Social Responsibility (CSR) from the perspective of governmental regulation as a measure to promote public policy interests through public-private regulation intended to influence firms’ self-regulation. Presenting a ‘government case’ for CSR, the connection between...... climate change and environmental sustainability, and social, economic and other human rights lend human rights as part of CSR a potential for meeting some environmental and climate concerns and handling adverse side-effects. The article analyses two EU initiatives: The EU Multi-Stakeholder (MSF) on CSR...

Reflexive regulation of CSR to promote sustainablility

DEFF Research Database (Denmark)

Buhmann, Karin

and the EU CSR Alliance. Focusing on human rights based in international law, it analyses the patterns of negotiation in the MSF and the background for the launch of the CSR Alliance. It shows that analysing public-private regulation of CSR from the perspective of reflexive law theory assists us......This article discusses Corporate Social Responsibility (CSR) from the perspective of governmental regulation as a measure to promote public policy interests through public-private regulation intended to influence firms’ self-regulation. Presenting a ‘government case’ for CSR, the connection between...... climate change and environmental sustainability, and social, economic and other human rights lend human rights as part of CSR a potential for meeting some environmental and climate concerns and handling adverse side-effects. The article analyses two EU initiatives: The EU Multi-Stakeholder (MSF) on CSR...

75 FR 59292 - Meeting of the Advisory Committee; Meeting

Science.gov (United States)

2010-09-27

... inclusion on future Joint Board examinations in actuarial mathematics, pension law and methodology referred... closed meeting of the Advisory Committee on Actuarial Examinations. DATES: The meeting will be held on... INFORMATION: Notice is hereby given that the Advisory Committee on Actuarial Examinations will meet at...

Proceedings of the meeting on uranium exploration, mining and extraction

International Nuclear Information System (INIS)

1996-01-01

Meeting on uranium exploration, mining, and extraction is aimed to expedite information exchange among researchers from the National Atomic Energy Agency (BATAN), their international colleagues, the higher education institutions,and other interested scientific communities on the latest development on Kalan uranium minerals exploration, mining, and extraction. Nuclear Minerals Development Centre (PPBGN) roles in nuclear energy provision, the theme of the meeting, reflect current advancements of the Centre in fulfilling its major tasks and responsibilities. In order to assist PPBGN better to assume its roles and responsibilities, the meeting is expected to bring forth essential solutions for problems and difficulties relevant to PPBGN's activities. Hence, the scope of the meeting will be limited to discussion on the status of nuclear minerals exploration, mining, and extraction technologies in Indonesia as well as the related environmental and workplace safeties in uranium mining and milling. Ten technical papers were presented in meeting, including four topics on exploration status and technology, three subject matter on mining, two presentations on milling, and one paper on environmental and workplace safeties

Political institutions of electricity regulation: The case of Turkey

International Nuclear Information System (INIS)

Mustafa Durakoglu, S.

2011-01-01

Turkey has been going through a liberalization process in its electricity market over the last decade. So far, the regulatory content of the market reforms has been in the center of attention in the literature, to the negligence of regulatory governance. However, recent studies, which applied the theoretical insights of new institutional economics to utilities regulation, have demonstrated that political endowments of the country draw the boundaries to which extent such regulatory content can be effectively implemented. In line with these studies, this paper adopts an institutional approach and attempts to identify the political endowments of Turkey in order to further analyze whether the market reforms succeeded in bringing about sufficient checks to cure the institutional problems. In other words, the paper takes a picture of the overall regulatory arena. The results show that the current regulatory structure, especially government-regulator relations, yet fails to meet good regulatory governance criteria. The paper also provides some policy suggestions. - Highlights: → Regulatory governance matters as much as regulatory content. → Political institutions draw boundaries to the implementation of regulatory content. → Market reforms have been insufficient to bring about a true institutional change. → Institutional checks must be devised to limit government interference to the market.

Water management: Current and future challenges and research directions

Science.gov (United States)

Cosgrove, William J.; Loucks, Daniel P.

2015-06-01

Water distinguishes our planet compared to all the others we know about. While the global supply of available freshwater is more than adequate to meet all current and foreseeable water demands, its spatial and temporal distributions are not. There are many regions where our freshwater resources are inadequate to meet domestic, economic development and environmental needs. In such regions, the lack of adequate clean water to meet human drinking water and sanitation needs is indeed a constraint on human health and productivity and hence on economic development as well as on the maintenance of a clean environment and healthy ecosystems. All of us involved in research must find ways to remove these constraints. We face multiple challenges in doing that, especially given a changing and uncertain future climate, and a rapidly growing population that is driving increased social and economic development, globalization, and urbanization. How best to meet these challenges requires research in all aspects of water management. Since 1965, the journal Water Resources Research has played an important role in reporting and disseminating current research related to managing the quantity and quality and cost of this resource. This paper identifies the issues facing water managers today and future research needed to better inform those who strive to create a more sustainable and desirable future.

INFOTECH `92: DOE Technical Information (TI) Meeting, October 21--23, 1992

Energy Technology Data Exchange (ETDEWEB)

Blanton, J.M.

1992-10-01

This proceedings contains papers presented at the 1992 Department of Energy (DOE) Technical Information Meeting held at the Office of Scientific and Technical Information (OSTI), Oak Ridge, Tennessee, October 21--23, 1992. It is composed of written presentation given orally at the meeting in either large-group or break-out sessions. The proceedings is provided as a reference tool for those who attended the meeting as well as an information document for those unable to attend. The annual DOE Technical Information meeting is designed for information professionals involved in the management of the Department`s scientific and technical information (STI). Speakers include members of the OSTI staff as well as DOE and DOE contractors and other invited specialists in the field of information. The major objective of the meeting is to provide a forum within the Department for discussing current and future information policies, trends, and management techniques as well as the technologies and standards available for managing and accessing scientific and technical information.

Netherlands in the spotlight at the ENLIGHT meeting on particle therapy

CERN Multimedia

Virginia Greco (CERN) and Manjit Dosanjh (ENLIGHT co-coordinator)

2016-01-01

The annual meeting of ENLIGHT, which focuses on particle therapy for cancer treatment, was held in the Netherlands.   Participants of the annual meeting of ENLIGHT, held in the Netherlands from 15-17 September 2016. The annual meeting of ENLIGHT (European Network for Light Hadron Therapy), which gathers experts working worldwide in centres and research institutions for particle therapy for cancer treatment, was hosted this year by the Dutch National Institute for Subatomic Physics (Nikhef) and the University of Utrecht, in the Netherlands, from 15-17 September. Chaired by the co-coordinator of ENLIGHT, Manjit Dosanjh, and the local organisers, Els Koffeman and Jan Visser from Nikhef, the meeting was attended by almost 100 participants from 15 countries. The Netherlands took centre stage at the ENLIGHT meeting: four brand new centres for proton therapy in the Netherlands are currently at various phases of completion as a consequence of the recent approval by the Dutch government of a plan for mak...

Annual technical meeting of the NRC cooperative severe accident research program

International Nuclear Information System (INIS)

Silver, E.G.

1993-01-01

This brief report summarizes the 1992 annual technical meeting of the NRC Cooperative Severe Accident Research Program (CSARP-92) held at the Hyatt Regency Hotel in Bethesda, Maryland, May 4-8, 1992. The report is taken mainly from coverage of the meeting published in the June 5, 1992, issue of Atomic Energy Clearinghouse. Results of this meeting are formalized at the Water Reactor Safety Information Meetings (WRSIM) that are held annually in October. Nuclear Safety summarizes the annual WRSIM meetings and provides a list of the presentations that were given. Interested readers are encouraged to review listed topics to identify specific topic areas in severe accident research. Sessions were held on in-vessel core melt progression; fuel-coolant interactions; fission-product behavior; direct containment heating; and severe accident code development, assessment, and validation. Summaries of the individual technical sessions and the current state of the art in these areas were given by the chairmen

Fusion safety regulations in the United States: Progress and trends

International Nuclear Information System (INIS)

DeLooper, J.

1994-01-01

This paper explores the issue of regulations as they apply to current and future fusion experimental machines. It addresses fusion regulatory issues, current regulations used for fusion, the Tokamak Fusion Test Reactor experience with regulations, and future regulations to achieve fusion's safety and environmental potential

Seasonality directs contrasting food collection behavior and nutrient regulation strategies in ants.

Directory of Open Access Journals (Sweden)

Steven C Cook

Full Text Available Long-lived animals, including social insects, often display seasonal shifts in foraging behavior. Foraging is ultimately a nutrient consumption exercise, but the effect of seasonality per se on changes in foraging behavior, particularly as it relates to nutrient regulation, is poorly understood. Here, we show that field-collected fire ant colonies, returned to the laboratory and maintained under identical photoperiod, temperature, and humidity regimes, and presented with experimental foods that had different protein (p to carbohydrate (c ratios, practice summer- and fall-specific foraging behaviors with respect to protein-carbohydrate regulation. Summer colonies increased the amount of food collected as the p:c ratio of their food became increasingly imbalanced, but fall colonies collected similar amounts of food regardless of the p:c ratio of their food. Choice experiments revealed that feeding was non-random, and that both fall and summer ants preferred carbohydrate-biased food. However, ants rarely ate all the food they collected, and their cached or discarded food always contained little carbohydrate relative to protein. From a nutrient regulation strategy, ants consumed most of the carbohydrate they collected, but regulated protein consumption to a similar level, regardless of season. We suggest that varied seasonal food collection behaviors and nutrient regulation strategies may be an adaptation that allows long-lived animals to meet current and future nutrient demands when nutrient-rich foods are abundant (e.g. spring and summer, and to conserve energy and be metabolically more efficient when nutritionally balanced foods are less abundant.

76 FR 17967 - Meeting of the Advisory Committee; Meeting

Science.gov (United States)

2011-03-31

... Joint Board examinations in actuarial mathematics, pension law and methodology referred to in 29 U.S.C... closed meeting of the Advisory Committee on Actuarial Examinations. DATES: The meeting will be held on... INFORMATION: Notice is hereby given that the Advisory Committee on Actuarial Examinations will meet at Mercer...

77 FR 19034 - Meeting of the Advisory Committee; Meeting

Science.gov (United States)

2012-03-29

... Joint Board examinations in actuarial mathematics, pension law and methodology referred to in 29 U.S.C... closed meeting of the Advisory Committee on Actuarial Examinations. DATES: The meeting will be held on... INFORMATION: Notice is hereby given that the Advisory Committee on Actuarial Examinations will meet at...

Developing a Systematic Education and Training Approach Using Personal Computer Based Simulators for Nuclear Power Programmes. Proceedings of a Technical Meeting

International Nuclear Information System (INIS)

2018-01-01

This publication compiles the output and findings of a technical meeting organized by the IAEA. The use of personal computer (PC) based basic principle simulators in education and training is aimed at enhancing understanding of nuclear technologies through “learning by doing”. This hands-on experiential training is highly suitable for operators, maintenance technicians, suppliers, regulators, students and engineers. Experts from 21 Member States, together with IAEA staff, presented the current status of the PC based basic principle simulators, their applications in education and training and identified relevant gaps and needs for improvements and/or new development. The resultant publication includes summaries of the presentations, follow-up discussions as well as conclusions and recommendations for possible future activities.

77 FR 62218 - Pacific Fishery Management Council; Public Meetings

Science.gov (United States)

2012-10-12

.... Preseason Salmon Management Schedule for 2013 3. 2012 Salmon Methodology Review D. Habitat 1. Current... Operating Procedures 4. Future Council Meeting Agenda and Workload Planning G. Coastal Pelagic Species... people with disabilities. Requests for sign language interpretation or other auxiliary aids should be...

75 FR 39934 - Oil and Natural Gas Sector-Notice of Public Meeting

Science.gov (United States)

2010-07-13

... an electronic or hard copy of any prepared comments be provided to EPA at the time of the meeting... materials are available either electronically through www.regulations.gov or in hard copy at the EPA Docket... requires, among other things, that EPA sign by January 31, 2011, proposed standards and/or determinations...

Current Evaluation of the Millennium Phytomedicine- Ginseng (I): Etymology, Pharmacognosy, Phytochemistry, Market and Regulations

Science.gov (United States)

Jia, Lee; Zhao, Yuqing

2009-01-01

The dawning of this millennium broke new ground in life science and technology, presented us genomic and proteomic revolution, nanotechnology innovation, and high performance liquid chromatography coupled with tandem mass spectrometry (LC/MS/MS) used for separating and identifying new chemical entities at pico-, or even femto-concentrations. Applications of these high technologies to the traditional Chinese medicine (TCM) opened a new chapter in the ancient medicine, and prompted us to re-evaluate the thousand-year-old phytomedicine–ginseng from current perspectives. We, therefore, collected the latest information (mostly within 10 years) on ginseng, and condensed the information into two parts of this review serial. The present part covers etymology of ginseng, its pharmacognosy (natural origin, physical appearance, chemical properties, and specie identification), its cultivation and processing-related metabolic changes in active ingredients, standardized analytical methods used for quality control of various ginseng products, modern analytical methods used to identify and classify more than 100 chemical entities (many were recently unfolded) derived from ginseng species and their metabolites. The global markets and production of ginseng and relevant government regulations are herein updated to exchange information and understandings about current people’s uses and cultivation of ginseng. The second part of the review serial will classify all these 100 chemical entities separated from various ginseng species into different groups based on their structural similarities, and summarize bioactivities of these entities. The second part of the review serial will also focus on recent findings of ginseng pharmacology and its clinical trials for various diseases, and brief side effects of ginseng. PMID:19601793

Current evaluation of the millennium phytomedicine--ginseng (I): etymology, pharmacognosy, phytochemistry, market and regulations.

Science.gov (United States)

Jia, Lee; Zhao, Yuqing

2009-01-01

The dawning of this millennium broke new ground in life science and technology, presented us genomic and proteomic revolution, nanotechnology innovation, and high performance liquid chromatography coupled with tandem mass spectrometry (LC/MS/MS) used for separating and identifying new chemical entities at pico-, or even femto-concentrations. Applications of these high technologies to the traditional Chinese medicine (TCM) opened a new chapter in the ancient medicine, and prompted us to re-evaluate the thousand-year-old phytomedicine- ginseng from current perspectives. We, therefore, collected the latest information (mostly within 10 years) on ginseng, and condensed the information into two parts of this review serial. The present part covers etymology of ginseng, its pharmacognosy (natural origin, physical appearance, chemical properties, and specie identification), its cultivation and processing-related metabolic changes in active ingredients, standardized analytical methods used for quality control of various ginseng products, modern analytical methods used to identify and classify more than 100 chemical entities (many were recently unfolded) derived from ginseng species and their metabolites. The global markets and production of ginseng and relevant government regulations are herein updated to exchange information and understandings about current people's uses and cultivation of ginseng. The second part of the review serial will classify all these 100 chemical entities separated from various ginseng species into different groups based on their structural similarities, and summarize bioactivities of these entities. The second part of the review serial will also focus on recent findings of ginseng pharmacology and its clinical trials for various diseases, and brief side effects of ginseng.

77 FR 30227 - Small Business Size Regulations, Small Business Innovation Research (SBIR) Program and Small...

Science.gov (United States)

2012-05-22

... Business Size Regulations, Small Business Innovation Research (SBIR) Program and Small Business Technology... public Webinar and Roundtable Meetings regarding its proposal to amend its regulations governing size and eligibility for the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR...

75 FR 34459 - Converged Communications and Health Care Devices Impact on Regulation; Public Meeting; Request...

Science.gov (United States)

2010-06-17

... jointly sponsoring a public meeting entitled ``Enabling the Convergence of Communications and Medical... scheduled to begin. If you need special accommodations due to a disability, please send an email to fcc504... and represent the convergence of communications and medicine include a smartphone application that...

CURRENT TRENDS IN DEVELOPING URBAN TOURISM

Directory of Open Access Journals (Sweden)

Selin Yıldız

2013-07-01

Full Text Available The synergy of architecture and other disciplines in studies of developing tourism is  significant in terms of continuity of past and future. Now architects and urban designers are working in collaboration with social sciences disciplines in the field of urban tourism. Some examples of cultural, artistic and social activities can be listed as: re-transformation of port districts, opening of new museums, new additions to the fabric of the historic city, theme parks, coastal regulations, re-use of historic structures, innovative approaches to accommodation services, production of the metropolitan centers, architectural competitions organized by central and local governments, prestige landscapes, innovative, technological and ecological approaches in architecture, festivals, design and fashion weeks, guided tours, city walks, local meetings, lectures, courses in art education, concerts, sport events, fairs , the cultural capitals. The paper analyses these works companion to tourism in detail and in a holistic sese, questions these studies in urban,  economic, cultural and social movement axes. This inquiry aims to discuss current  projects being carried out in Istanbul which is an important city in the world, also to offer a wide range of tips for conducting a collaborative, multi-dimensional perspective studies carried out in the field of tourism.

Proceedings of the CSNI Specialist Meeting on Transient Two-Phase Flow - Current Issues in System Thermal Hydraulics

Energy Technology Data Exchange (ETDEWEB)

Reocreux, M; Rubinstein, M C [CEA-IPSN/DRS/SEMAR, Centre d' Etudes Nucleaires de Cadarache, 13108 Saint Paul-lez-Durance (France)

1992-07-01

The 4. Specialists' Meeting on Transient Two Phase Flow was organized by the Safety Research Department of the French Nuclear Safety and Protection Institute at the request of the OECD Committee for the Safety of Nuclear Installations. After Toronto in 1976, Paris in 1978 and Pasadena in 1981, the Aix-en-Provence meeting was in keeping with the course of studies initiated by the Thermalhydraulic Systems Behavior Task Group of the Principal Working Group No.2 for discussing the achievements and defining the needs of safety research in accident thermal-hydraulics. 60 Specialists from 14 Countries (Belgium, Canada, Finland, France, Germany, Italy, Japan, the Netherlands, the United Kingdom, the USA, Spain, Sweden, Switzerland, Taiwan) attended the meeting, representing a large spectrum of experts from National Safety Authorities, Research Laboratories, Universities, Vendors and Utilities. These specialists had to review the 15-year research period which had elapsed since the last meetings. This period had been characterized by the issuance of the large thermalhydraulic computer codes for LWR accidents, the performance of several hundreds of separate effect tests for the development and the qualification of the physical models, the carrying-out of the large experimental programmes on system loops (up to scale 1) for verifying the computer codes. Although this research was mainly characterized by remarkable success, limitations still exist. In a safety approach, there need to be well identified and handled, and the specialists were asked to exchange their views in order to determine which solutions they expected to be affordable in the future. Safety applications have already started which use these latest research achievements. They raise specific problems such as the use of validation matrices, the evaluation of uncertainties, the identification and the control of unavoidable users' effects. The specialists were required to exchange their experience of applications

Proceedings of the CSNI Specialist Meeting on Transient Two-Phase Flow - Current Issues in System Thermal Hydraulics

International Nuclear Information System (INIS)

Reocreux, M.; Rubinstein, M.C.

1992-01-01

The 4. Specialists' Meeting on Transient Two Phase Flow was organized by the Safety Research Department of the French Nuclear Safety and Protection Institute at the request of the OECD Committee for the Safety of Nuclear Installations. After Toronto in 1976, Paris in 1978 and Pasadena in 1981, the Aix-en-Provence meeting was in keeping with the course of studies initiated by the Thermalhydraulic Systems Behavior Task Group of the Principal Working Group No.2 for discussing the achievements and defining the needs of safety research in accident thermal-hydraulics. 60 Specialists from 14 Countries (Belgium, Canada, Finland, France, Germany, Italy, Japan, the Netherlands, the United Kingdom, the USA, Spain, Sweden, Switzerland, Taiwan) attended the meeting, representing a large spectrum of experts from National Safety Authorities, Research Laboratories, Universities, Vendors and Utilities. These specialists had to review the 15-year research period which had elapsed since the last meetings. This period had been characterized by the issuance of the large thermalhydraulic computer codes for LWR accidents, the performance of several hundreds of separate effect tests for the development and the qualification of the physical models, the carrying-out of the large experimental programmes on system loops (up to scale 1) for verifying the computer codes. Although this research was mainly characterized by remarkable success, limitations still exist. In a safety approach, there need to be well identified and handled, and the specialists were asked to exchange their views in order to determine which solutions they expected to be affordable in the future. Safety applications have already started which use these latest research achievements. They raise specific problems such as the use of validation matrices, the evaluation of uncertainties, the identification and the control of unavoidable users' effects. The specialists were required to exchange their experience of applications

77 FR 59979 - Meeting of the Advisory Committee; Meeting

Science.gov (United States)

2012-10-01

... actuarial mathematics, pension law and methodology referred to in 29 U.S.C. 1242(a)(1)(B). A determination... closed meeting of the Advisory Committee on Actuarial Examinations. DATES: The meeting will be held on... is hereby given that the Advisory Committee on Actuarial Examinations will meet at Towers Watson, 800...

German Society for Immunology and Australasian Society for Immunology joint Workshop 3(rd) -4(th) December 2015 - Meeting report.

Science.gov (United States)

Kurts, Christian; Gottschalk, Catherine; Bedoui, Sammy; Heinzel, Susanne; Godfrey, Dale; Enders, Anselm

2016-02-01

The German Society for Immunology (DGfI) and the Australasian Society for Immunology (ASI) hosted the first DGfI-ASI joint workshop from December 3-4, 2015 in Canberra, Australia. A delegation of 15 distinguished German immunologists discussed the workshop topic "immune regulation in infections and immune mediated diseases" with the aim to establish new German-Australasian collaborations, discuss new concepts in the field of immune regulation and build a scientific network to create more utilizable resources for excellent (trans-border) immunological research. The workshop was associated with the 45(th) Annual Scientific Meeting of the ASI held from Nov 29-Dec 3, 2015, opening up even more opportunities for finding new collaboration partners. A return meeting will be linked to the annual DGfI meeting that will take place in 2017 in Erlangen. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Summary of the ACRE inaugural meeting.

Science.gov (United States)

Bloomgarden, Zachary T

2009-01-01

The charter meeting of the Association of Clinical Researchers and Educators (ACRE) provided a powerful set of arguments against assertions that physician-industry collaboration is harmful and represents a "conflict of interest." Such collaboration has, in fact, improved medical care for patients, a case made overwhelmingly by patients and patient advocacy groups at the meeting. The contentions that physician-industry collaboration is problematic are not based on evidence. They depend on unjustified generalization from inevitable, sometimes egregious, but vanishingly uncommon adverse outcomes of industry-physician interaction without reference to how so much more commonly these interactions add value. Furthermore, the claim that physician-industry collaboration is unprofessional is refuted by rational scrutiny. Indeed, the term "conflict of interest" itself is vague, inviting subjectivity and deserving to be rejected. The unwarranted success of conflict of interest regulation has prevailed because of the failure of physicians, educators, and innovators, through apathy and intimidation, to pay attention to its fallacies and resist its dangers. It has arisen from activist ambitions and from misalignment between the purposes of medical practitioners, educators, and innovators and those of administrators in medical journals and in academic medical centers. The media and politicians have not appreciated these misalignments and have accepted conflict of interest arguments at face value. Regulation emanating from conflict of interest criticism is confusing, onerous, expensive, disrespectful, and damaging. Prohibitions against speaking about medical products inhibit physician and patient education concerning rapidly emerging and complex therapies. Input by physicians cognizant of compliance requirements into such presentations should be encouraged. Restrictions to the free flow of corporate support of academic health centers, professional societies, and patient

Planning and conducting meetings effectively, part I: planning a meeting.

Science.gov (United States)

Harolds, Jay

2011-12-01

Meetings are held by leaders for many purposes, including conveying information, raising morale, asking for opinions, brain storming, making people part of the problem-solving process, building trust, getting to a consensus, and making decisions. However, many meetings waste time, some undermine the leader's power, and some decrease morale. Part I of this series of articles gives some tips on basic planning for decision-making meetings. Part II of this series of articles analyzes selected components of decision-making meetings. Part III of this series will be on how the chairperson keeps decision-making meetings on track to make them efficient and productive.

Team self-regulation and meeting deadlines in project teams: antecedents and effects of temporal consensus

NARCIS (Netherlands)

Gevers, J.M.P.; van Eerde, W.; Rutte, C.G.

2009-01-01

In a longitudinal study among 48 project teams, we investigated how temporal consensus (i.e., the extent to which team members have a shared understanding of the temporal aspects of their collective task) affects the ability of teams to establish coordinated action and meet deadlines. In addition,

CONSIDERATIONS REGARDING REGULATIONS ON FINANCIAL MARKETS IN THE CONDITIONS OF ROMANIA AS A EU MEMBER STATE

Directory of Open Access Journals (Sweden)

ALEXANDRU CRISTIAN DOBRE

2018-02-01

Full Text Available Financial markets are increasingly becoming an area of major interest to the European Union in its efforts to achieve competitive global development levels similar to those of the United States. The Lisbon Agenda is a testimony to this, although the latest assessments are not at all optimistic about the achievement of the target as expected for 2010. To meet its objectives, the EU has generated a comprehensive package of regulatory initiatives, composed of directives and regulations that translate its policies into the field. The paper aims at a careful review of all of them. Approximation of investment and capital markets is made from the two major chapters of Community policies whose freedom of movement within the internal market is a fundamental desideratum of the European Union: the free movement of capital and freedom of movement of services. Financial markets are an integral part of European capital under current conditions, so development regulation helps European Union member states achieve their financial goals. At the same time, by imposing these regulations, we observe the European Union's intention to act as a starter of systems to bring to the development of states and not to leave behind the countries that are in difficulty, through a rigorous and transparent regulation of the financial markets.

Aldosterone down-regulates the slowly activated delayed rectifier potassium current in adult guinea pig cardiomyocytes.

Science.gov (United States)

Lv, Yankun; Bai, Song; Zhang, Hua; Zhang, Hongxue; Meng, Jing; Li, Li; Xu, Yanfang

2015-12-01

There is emerging evidence that the mineralocorticoid hormone aldosterone is associated with arrhythmias in cardiovascular disease. However, the effect of aldosterone on the slowly activated delayed rectifier potassium current (IK s ) remains poorly understood. The present study was designed to investigate the modulation of IK s by aldosterone. Adult guinea pigs were treated with aldosterone for 28 days via osmotic pumps. Standard glass microelectrode recordings and whole-cell patch-clamp techniques were used to record action potentials in papillary muscles and IK s in ventricular cardiomyocytes. The aldosterone-treated animals exhibited a prolongation of the QT interval and action potential duration with a higher incidence of early afterdepolarizations. Patch-clamp recordings showed a significant down-regulation of IK s density in the ventricular myocytes of these treated animals. These aldosterone-induced electrophysiological changes were fully prevented by a combined treatment with spironolactone, a mineralocorticoid receptor (MR) antagonist. In addition, in in vitro cultured ventricular cardiomyocytes, treatment with aldosterone (sustained exposure for 24 h) decreased the IK s density in a concentration-dependent manner. Furthermore, a significant corresponding reduction in the mRNA/protein expression of IKs channel pore and auxiliary subunits, KCNQ1 and KCNE1 was detected in ventricular tissue from the aldosterone-treated animals. Aldosterone down-regulates IK s by inhibiting the expression of KCNQ1 and KCNE1, thus delaying the ventricular repolarization. These results provide new insights into the mechanism underlying K(+) channel remodelling in heart disease and may explain the highly beneficial effects of MR antagonists in HF. © 2015 The British Pharmacological Society.

The South African nursing council: 50 years of professional self-regulation

Directory of Open Access Journals (Sweden)

W. J. Kotzé

1995-03-01

Full Text Available Self-regulation of the professions of nursing and midwifery became a reality in South Africa on 8 November 1944, when the first council meeting of the South African Nursing Council took place in Pretoria. Most appropriately, the opening speaker on this occasion was Mr Harry Gordon Lawrence, the Minister of Welfare and Demobilization, who had piloted the Nursing Act, No.45 of 1944, through Parliament. Exactly 50 years later, on 8 November 1994 the Council held its 108th meeting, this time in its own building, with a magnificent view of the venue where that historic first meeting took place - the west wing of the Union buildings.

Passive safety features in current and future water cooled reactors

International Nuclear Information System (INIS)

1990-11-01

Better understanding of the passive safety systems and components in current and future water-cooled reactors may enhance the safety of present reactors, to the extend passive features are backfitted. This better understanding should also improve the safety of future reactors, which can incorporate more of these features. Passive safety systems and components may help to prevent accidents, core damage, or release radionuclides to the environment. The Technical Committee Meeting which was hosted by the USSR State Committee for Utilization of Nuclear Energy was attended by about 80 experts from 16 IAEA Member States and the NEA-OECD. A total of 21 papers were presented during the meeting. The objective of the meeting was to review and discuss passive safety systems and features of current and future water cooled reactor designs and to exchange information in this area of activity. A separate abstract was prepared for each of the 21 papers published in this proceedings. Refs, figs and tabs

77 FR 46067 - Multistakeholder Meetings To Develop Consumer Data Privacy Code of Conduct Concerning Mobile...

Science.gov (United States)

2012-08-02

...-application-transparency , for the most current information. Place: The meetings will be held in the...-process-mobile-application-transparency , for the most current information. Other Information: The...-application-transparency , for the most current information. Dated: July 30, 2012. Kathy D. Smith, Chief...

Report on the Survey on Regulation of Site Selection and Preparation

International Nuclear Information System (INIS)

Webster, Philip

2010-01-01

At its first meeting in May 2008, the Working Group discussed a task to 'Prepare a report reviewing the various practices used by regulators in the regulation of nuclear power plant siting. The report should consider regulator practices on sites where a mixture of activities are taking place (e.g. operating units, new construction, decommissioning, etc) including organization of the regulators organisation, methods, systems, etc.'. Following discussion, the Working Group assigned an Action 1-5 to 'develop a survey on the regulation of nuclear sites including seismicity issues, security issues, multi-units aspects and regulator practices on sites where a mixture of activities are taking place (e.g. operating units, new construction, decommissioning, etc.)'. The Survey was prepared and issued by the NEA in July 2008 with a request to the member states to provide their responses by the next meeting of the Working Group in October 2008. In addition to addressing the specific topics actioned by the Working Group, the Survey also investigated the broader context of siting, in order to address the Mandate that had been approved by the CNRA. The questions in the survey therefore covered the topics of site evaluation, site selection, regulatory approval, site preparation and regulatory oversight. A topic of particular interest was to what extent IAEA guidance on site evaluation was followed. The survey considered the possibility that a body other than the safety regulator may approve the choice of site or permit the applicant to start to prepare it. The survey also investigated the existence of formal requirements and informal expectations, recognizing that these both form part of the regulatory tool-kit. Responses were received from all twelve member states that were then members of the Working Group. The responses were reviewed at the second meeting of the Working Group in October 2008. In general, it could be stated that new reactors are licensed in

Using geospatial solutions to meet distribution integrity management requirements

Energy Technology Data Exchange (ETDEWEB)

McElroy, Robert A. [New Century Software, Inc., Fort Collins, CO (United States)

2010-07-01

In the United States, incidents on gas distribution pipelines kill on average 10 persons per year in addition to causing 40 serious injuries and millions of dollars of property damage. In order to remedy to this situation, the US Department of Transportation/Pipeline Hazardous Materials Safety Administration enacted new regulations requiring operators to develop distribution integrity management programs (DIMP) which must include: knowledge and identification of threats, evaluation of risk, identification and implementation of measures to address risks, performance measuring, periodic evaluation and improvement and results reporting. The aim of this paper is to show how geographic information systems (GIS) can help operators meet each requirement of the DIMP regulations. This discussion showed that GIS can help in identifying and quantifying the threats to the distribution system and in assessing the consequences of an incident. Investing in GIS will not only help operators in complying with the regulations but will also help them make economically sound, risk-based decisions.

STANDING CONCERTATION COMMITTEE ORDINARY MEETING ON 17 NOVEMBER 1999

CERN Document Server

1999-01-01

This meeting essentially dealt with the various items below:Follow-up of the Finance Committee meeting and preparation for the TREF meeting in NovemberIn November, the Finance Committee recommended the Council to apply the calculated indices for basic salaries (1.292%) and pensions (1.3%) with effect from 1st January 2000. In addition, some voting procedure issues raised during the meeting need to be clarified. Following a question on the consequences of the scheduled downsizing of the staff complement, the Finance Committee agreed that it would be appropriate to await the results of a current internal study on that issue, which were expected to be available by June 2000. The SCC took note of the final preparations for TREF on19 November, with special reference to two items concerning the Pension Fund: compensation to the Fund for the reduction in staff numbers in 1998 and the second stage in the examination of pension guarantee questions. After taking note of the report drawn up by the external experts on pe...

Establishment of A+M Computer Code Network. Summary report of IAEA technical meeting

International Nuclear Information System (INIS)

Clark, R.E.H.

2006-01-01

Eleven international experts on computational aspects of atomic and molecular data for fusion energy research participated in a technical meeting arranged to discuss the establishment of an A and M Computer Code Network, and held at IAEA Headquarters on 23-25 May 2005. Each participant reviewed the current status of their own speciality and current lines of research, as well as anticipated needs in new data for nuclear fusion energy research. A preliminary method for making these valuable resources more readily available was outlined, and implementation will proceed. Several of the computational tools presented are already available through Internet connections. All the goals of the meeting were achieved, and every participant indicated a desire to see more collaboration and cooperation in fulfilling the A and M data needs for fusion. The discussions, conclusions and recommendations of the meeting are briefly described in this report. (author)

Transparency in Nuclear Regulation: Trends and Future Prospects

International Nuclear Information System (INIS)

Choi, Kwang Sik; Choi, Young Sung; Kim, Seong Ho

2007-01-01

Recently, improving transparency (or openness) has been one of important issues related to nuclear safety worldwide. As for the transparency in nuclear regulatory activities in Korea, openness has been declared as one of five principles of the nuclear regulation in the 'nuclear safety policy statement' announced in 1994. Transparency has been discussed and emphasized in various international meetings such as the Convention on Nuclear Safety, OECD/NEA meetings, etc. For example, Working Group on Public Communication of nuclear regulatory organizations (WGPC) of the OECD/NEA/CNRA held a workshop on 'the transparency of nuclear regulatory activities' in May 2007 in Tokyo, Japan. In this paper, definition of transparency and its international trends ranging from a general administration to nuclear safety activities are discussed based on the results of meetings and workshops held so far. Measures for improvement associated with transparency are also proposed

Standing Concertation Commmittee - Ordinary meeting on 10 May 2007

CERN Multimedia

2007-01-01

At its meeting on 10 May 2007, the Standing Concertation Committee discussed the Management’s proposal for the revision of Annex A 1 of the Staff Rules and Regulations. Annex A 1 sets out the principles for future periodic reviews of the personnel’s financial and social conditions and the revision reflects the modifications to review methods decided by the CERN Council in December 2006. The aim is to simplify the processes involved and rationalize the use of resources. The data collection process will be outsourced to a greater extent. The new methods also aim to reduce the overall time required to complete future reviews. Details of procedure will be addressed in subsequent discussions. The Committee approved the document for submission to the Tripartite Employment Conditions Forum (TREF) at its meeting on 31 May and 1 June 2007.

Standing Concertation Commmittee - Ordinary meeting on 10 May 2007

CERN Multimedia

HR Department

2007-01-01

At its meeting on 10 May 2007, the Standing Concertation Committee discussed the Management's proposal for the revision of Annex A 1 of the Staff Rules and Regulations. Annex A 1 sets out the principles for future periodic reviews of the personnel's financial and social conditions and the revision reflects the modifications to review methods decided by the CERN Council in December 2006. The aim is to simplify the processes involved and rationalize the use of resources. The data collection process will be outsourced to a greater extent. The new methods also aim to reduce the overall time required to complete future reviews. Details of procedure will be addressed in subsequent discussions. The Committee approved the document for submission to the Tripartite Employment Conditions Forum (TREF) at its meeting on 31 May and 1 June 2007.

78 FR 59336 - Codex Alimentarius Commission: Meeting of the Codex Committee on Food Hygiene

Science.gov (United States)

2013-09-26

... . Options range from recalls to export information to regulations, directives and notices. Customers can add... October 23, 2013. The objective of the public meeting is to provide information and receive public... FDA recognize the importance of providing interested parties the opportunity to obtain background...

Tumor radiosensitizers - current status of development of various approaches: Report of an International Atomic Energy Agency meeting

DEFF Research Database (Denmark)

Horsman, Michael Robert; Bohm, Lothar; Margison, Geoffrey P.

2006-01-01

PURPOSE: The International Atomic Energy Agency (IAEA) held a Technical Meeting of Consultants to (1) discuss a selection of relatively new agents, not those well-established in clinical practice, that operated through a variety of mechanisms to sensitize tumors to radiation and (2) to compare...... and contrast their tumor efficacy, normal tissue toxicity, and status of development regarding clinical application. The aim was to advise the IAEA as to which developing agent or class of agents would be worth promoting further, by supporting additional laboratory research or clinical trials...... and for clinical trials that would be suitable for industrialized countries, as well as trials that were considered more appropriate for developing countries.PURPOSE: The International Atomic Energy Agency (IAEA) held a Technical Meeting of Consultants to (1) discuss a selection of relatively new agents, not those...

76 FR 65563 - Genomic Medicine Program Advisory Committee; Notice of Meeting

Science.gov (United States)

2011-10-21

... oversight and protecting the privacy of Veterans. The meeting focus will be on current and upcoming... recommendations to the Secretary of Veterans Affairs on using genetic information to optimize medical care of...

PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP, RHIC SPIN COLLABORATION MEETING VI, VOLUME 36

International Nuclear Information System (INIS)

BLAND, L.; SAITO, N.

2001-01-01

The sixth meeting of the RHIC Spin Collaboration (RSC) took place on October 1, 2001 at Brookhaven National Laboratory. RHIC is now in its second year of operation for physics production and the first polarized proton collision run at √s=200 GeV is expected to start in eight weeks. The RSC has developed a plan for this coming run through two previous meetings, RHIC Spin Physics III (August 3, 2000) and IV (October 13-14, 2000). We requested the following: two weeks of polarized proton studies in AGS, three weeks of polarized collider commissioning, and five weeks of polarized proton physics run. As a result, we have obtained all we asked and the above plans are implemented in the current operation schedule. The focus of the present meeting was to bring all involved in the RHIC Spin activities up-to-date on the progress of machine development, theory issues, and experimental issues. This meeting was right after the Program Advisory Committee (PAC) meeting and it started with the comments on the PAC discussion by Gerry Bunce, who was informed about the PAC deliberations by Tom Kirk. The PAC was fully supportive to complete the proposed spin program within the currently available budget for RHIC run 2 operations. Gerry further explained the expected luminosity to be ∫ Ldt = 0.5 pb -1 per week, reflecting the current machine status. The introductory session also had a talk from Werner Vogelsang that reviewed the progress in perturbative QCD theory focused on spin effects

Metabotropic Regulation of Extrasynaptic GABAA Receptors

Directory of Open Access Journals (Sweden)

William Martin Connelly

2013-10-01

Full Text Available A large body of work now shows the importance of GABAA receptor-mediated tonic inhibition in regulating CNS function. However, outside of pathological conditions, there is relatively little evidence that the magnitude of tonic inhibition is itself under regulation. Here we review the mechanisms by which tonic inhibition is known to be modulated, and outline the potential behavioural consequences of this modulation. Specifically, we address the ability of protein kinase A and C to phosphorylate the extrasynaptic receptors responsible for the tonic GABAA current, and how G-protein coupled receptors can regulate tonic inhibition through these effectors. We then speculate about the possible functional consequences of regulating the magnitude of the tonic GABAA current.

Distributed Nonlinear Control with Event-Triggered Communication to Achieve Current-Sharing and Voltage Regulation in DC Microgrids

DEFF Research Database (Denmark)

Han, Renke; Meng, Lexuan; Guerrero, Josep M.

2018-01-01

combining the state-dependent tolerance with a nonnegative offset. In order to design the event-triggered principle and guarantee the global stability, a generalized dc microgrid model is proposed and proven to be positive definite, based on which Lyapunov-based approach is applied. Furthermore, considering......A distributed nonlinear controller is presented to achieve both accurate current-sharing and voltage regulation simultaneously in dc microgrids considering different line impedances’ effects among converters. Then, an improved event-triggered principle for the controller is introduced through...... for precise real-time information transmission, without sacrificing system performance. Experimental results obtained from a dc microgrid setup show the robustness of the new proposal under normal, communication failure, communication delay and plug-and-play operation conditions. Finally, communication...

Virulence meets metabolism: Cra and KdpE gene regulation in enterohemorrhagic Escherichia coli.

Science.gov (United States)

Njoroge, Jacqueline W; Nguyen, Y; Curtis, Meredith M; Moreira, Cristiano G; Sperandio, Vanessa

2012-10-16

Gastrointestinal (GI) bacteria sense diverse environmental signals as cues for differential gene regulation and niche adaptation. Pathogens such as enterohemorrhagic Escherichia coli (EHEC), which causes bloody diarrhea, use these signals for the temporal and energy-efficient regulation of their virulence factors. One of the main virulence strategies employed by EHEC is the formation of attaching and effacing (AE) lesions on enterocytes. Most of the genes necessary for the formation of these lesions are grouped within a pathogenicity island, the locus of enterocyte effacement (LEE), whose expression requires the LEE-encoded regulator Ler. Here we show that growth of EHEC in glycolytic environments inhibits the expression of ler and consequently all other LEE genes. Conversely, growth within a gluconeogenic environment activates expression of these genes. This sugar-dependent regulation is achieved through two transcription factors: KdpE and Cra. Both Cra and KdpE directly bind to the ler promoter, and Cra's affinity to this promoter is catabolite dependent. Moreover, we show that the Cra and KdpE proteins interact in vitro and that KdpE's ability to bind DNA is enhanced by the presence of Cra. Cra is important for AE lesion formation, and KdpE contributes to this Cra-dependent regulation. The deletion of cra and kdpE resulted in the ablation of AE lesions. One of the many challenges that bacteria face within the GI tract is to successfully compete for carbon sources. Linking carbon metabolism to the precise coordination of virulence expression is a key step in the adaptation of pathogens to the GI environment. IMPORTANCE An appropriate and prompt response to environmental cues is crucial for bacterial survival. Cra and KdpE are two proteins found in both nonpathogenic and pathogenic bacteria that regulate genes in response to differences in metabolite concentration. In this work, we show that, in the deadly pathogen enterohemorrhagic Escherichia coli (EHEC) O157:H7

AMFIE Information meetings

CERN Multimedia

2012-01-01

Meetings open to all members of personnel (users, staff, etc) as well as retired staff.   Public presentation with question/answer session Wednesday 18 April 2012 From 12:00 to 13:00 In room 40-2-A01 Private consultations on appointment Wednesday 18 April 2012 From 10:00 to 11:30 and from 14:00 to 17:30 In room 5-5-028 AMFIE is a cooperative society open exclusively to international civil servants. It is managed by a group of active and retired international civil servants. Created in 1990 as a fully licensed financial institution, it is subject to the laws and regulations which govern the activities of Luxembourg's financial sector. The Cooperative offers its members a broad range of financial services and products at little or no cost in the six currencies available to account holders (EUR, CHF, GBP, USD, CAD, AUD). More information here. HR Department Tel. 74125

76 FR 24573 - Genomic Medicine Program Advisory Committee; Notice of Meeting

Science.gov (United States)

2011-05-02

... appropriate ethical oversight and protecting the privacy of Veterans. The meeting focus will be on current and... recommendations to the Secretary of Veterans Affairs on using genetic information to optimize medical care of...

Nuclear theory summer meeting on ERHIC

International Nuclear Information System (INIS)

McLerran, L.; Venugopalan, R.

2000-01-01

The eRHIC BNL summer meeting was held at BNL from June 26 to July 14, 2000. The meeting was very informal with only two talks a day and with ample time for discussions and collaborations. Several of the theory talks focused on the issue of saturation of parton distributions at small x--whether screening effects have already been seen at HERA, the relation of saturation to shadowing, and on the various signatures of a proposed novel state of matter--the Colored Glass Condensate--that may be observed at eRHIC. A related topic that was addressed was that of quantifying twist four effects, and on the relevance of these for studies of energy loss. Other issues addressed were coherence effects in vector meson production, anti-quark distributions in nuclei, and the relevance of saturation for heavy ion collisions. There were, also, talks on the Pomeron--the relevance of instantons and the non-perturbative gluon condensate to constructing a Pomeron. On the spin physics side, there were talks on predictions for inclusive distributions at small x. There were also talks on Skewed Parton Distributions and Deeply Virtual Compton Scattering. Though most of the talks were theory talks, there were also several important experimental contributions. A preliminary detector design for eRHIC was presented. Studies for semi-inclusive measurements at eRHIC were also presented. The current status of pA scattering studies at RHIC was also discussed. The eRHIC summer meeting provided a vigorous discussion of the current status of eRHIC studies. It is hoped that this document summarizing these discussions will be of use to all those interested in electron nucleus and polarized electron-polarized proton studies

An Evaluation of a High Pressure Regulator for NASA's Robotic Lunar Lander Spacecraft

Science.gov (United States)

Burnside, Christopher G.; Trinh, Huu P.; Pedersen, Kevin W.

2013-01-01

The Robotic Lunar Lander (RLL) development project office at NASA Marshall Space Flight Center is currently studying several lunar surface science mission concepts. The focus is on spacecraft carrying multiple science instruments and power systems that will allow extended operations on the lunar surface or other air-less bodies in the solar system. Initial trade studies of launch vehicle options indicate the spacecraft will be significantly mass and volume constrained. Because of the investment by the DOD in low mass, highly volume efficient components, NASA has investigated the potential integration of some of these technologies in space science applications. A 10,000 psig helium pressure regulator test activity has been conducted as part of the overall risk reduction testing for the RLL spacecraft. The regulator was subjected to typical NASA acceptance testing to assess the regulator response to the expected RLL mission requirements. The test results show the regulator can supply helium at a stable outlet pressure of 740 psig within a +/- 5% tolerance band and maintain a lock-up pressure less than the +5% above nominal outlet pressure for all tests conducted. Numerous leak tests demonstrated leakage less than 10-3 standard cubic centimeters per second (SCCS) for the internal seat leakage at lock-up and less than 10-5 SCCS for external leakage through the regulator body. The successful test has shown the potential for 10,000 psig helium systems in NASA spacecraft and has reduced risk associated with hardware availability and hardware ability to meet RLL mission requirements.

Hazardous materials package performance regulations

International Nuclear Information System (INIS)

Russell, N.A.; Glass, R.E.; McClure, J.D.; Finley, N.C.

1992-01-01

The hazardous materials (hazmat) packaging development and certification process is currently defined by two different regulatory philosophies, one based on specification packagings and the other based on performance standards. With specification packagings, a packaging is constructed according to an agreed set of design specifications. In contrast, performance standards do not specify the packaging design; they specify performance standards that a packaging design must be able to pass before it can be certified for transport. The packaging can be designed according to individual needs as long as it meets these performance standards. Performance standards have been used nationally and internationally for about 40 years to certify radioactive materials (RAM) packagings. It is reasonable to state that for RAM transport, performance specifications have maintained transport safety. A committee of United Nation's experts recommended the performance standard philosophy as the preferred regulation method for hazmat packaging. Performance standards for hazmat packagings smaller than 118 gallons have been adopted in 49CFR178. Packagings for materials that are classified as toxic-by-inhalation must comply with the performance standards by October 1, 1993, and packagings for all other classes of hazardous materials covered must comply by October 1, 1996. For packages containing bulk (in excess of 188 gallons) quantities of materials that are extremely toxic by inhalation, there currently are no performance requirements. This paper discusses a Hazmat Packaging Performance Evaluation (HPPE) project to look at the subset of bulk packagings that are larger than 2000 gallons. The objectives of this project are the evaluate current hazmat specification packagings and develop supporting documentation for determining performance requirements for packagings in excess of 2000 gallons that transport hazardous materials that have been classified as extremely toxic by inhalation (METBI)

The new look for radiation regulation

International Nuclear Information System (INIS)

Loy, J.

1999-01-01

The Australian Radiation Protection and Nuclear Safety Act (1998) provides the CEO of the Australian Radiation Protection and Nuclear Safety Agency with responsibilities related to researching and advising on radiation protection and nuclear safety, and powers to regulate the Commonwealth's use of radiation and nuclear facilities. This regulation is new to Commonwealth departments and agencies. To support the CEO in meeting these responsibilities and exercising the regulatory powers, the Act also establishes a new advisory council and two advisory committees. Other novel aspects of the Act include a public consultation process for applications for licence related to nuclear facilities, and a regime of quarterly reporting by the CEO to Parliament, in addition to the usual requirements for annual reports

77 FR 54568 - Meeting of the Defense Advisory Committee on Women in the Services (DACOWITS)

Science.gov (United States)

2012-09-05

... briefings from the Services on their current retention programs, a briefing from the Army on their gender neutral standards, and a briefing on Australian Defence Force gender restrictions and development and... make an oral presentation of their issue during an open portion of this meeting or at a future meeting...

Meetings as a positive boost? How and when meeting satisfaction impacts employee empowerment

NARCIS (Netherlands)

Allen, J.A.; Lehmann-Willenbrock, N.K.; Sands, S.

2016-01-01

Meetings constitute an important context for understanding organizational behavior and employee attitudes. Employees spend ever-increasing time in meetings and often complain about their meetings. In contrast, we explore the positive side of meetings and argue that satisfying meetings can empower

ACRF Archive User Meeting Summary

Energy Technology Data Exchange (ETDEWEB)

SA Edgerton; RA McCord; DP Kaiser

2007-10-30

On October 30, 2007, the U.S. Department of Energy’s (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility (ACRF) sponsored an all-day workshop to assess the status of the ACRF Archive. Focus areas included usability of current functions, plans for revised functions, proposals for new functions, and an overarching discussion of new ideas. Although 13 scientists familiar with ACRF and the ARM Program were invited to the workshop, only 10 scientists were available to attend the workshop. ACRF consists of the infrastructure that was developed to support the ARM Program and includes the ACRF Archive (previously called the ARM Archive). The scientists who participated in the meeting ranged from those who used the Archive frequently to those who seldom or never had accessed the Archive. The group was spread across disciplines, i.e. modelers, conservationists, and others from universities and government laboratories. A few of the participants were funded by the ARM Program, but most were not funded currently by ARM. During the past year, several improvements were made to the ACRF Archive to link it with the ARM/ACRF web pages, add a shopping cart feature, and expand on search parameters. Additional modifications have been proposed and prototypes of these proposals were made available for the participants. The participants were given several exercises to do before the meeting, and their feedback was requested to help identify potential problems and shortcomings with the existing structure and to recommend improvements.

Quantitative analysis of the Ca2+ -dependent regulation of delayed rectifier K+ current IKs in rabbit ventricular myocytes.

Science.gov (United States)

Bartos, Daniel C; Morotti, Stefano; Ginsburg, Kenneth S; Grandi, Eleonora; Bers, Donald M

2017-04-01

[Ca 2+ ] i enhanced rabbit ventricular slowly activating delayed rectifier K + current (I Ks ) by negatively shifting the voltage dependence of activation and slowing deactivation, similar to perfusion of isoproterenol. Rabbit ventricular rapidly activating delayed rectifier K + current (I Kr ) amplitude and voltage dependence were unaffected by high [Ca 2+ ] i . When measuring or simulating I Ks during an action potential, I Ks was not different during a physiological Ca 2+ transient or when [Ca 2+ ] i was buffered to 500 nm. The slowly activating delayed rectifier K + current (I Ks ) contributes to repolarization of the cardiac action potential (AP). Intracellular Ca 2+ ([Ca 2+ ] i ) and β-adrenergic receptor (β-AR) stimulation modulate I Ks amplitude and kinetics, but details of these important I Ks regulators and their interaction are limited. We assessed the [Ca 2+ ] i dependence of I Ks in steady-state conditions and with dynamically changing membrane potential and [Ca 2+ ] i during an AP. I Ks was recorded from freshly isolated rabbit ventricular myocytes using whole-cell patch clamp. With intracellular pipette solutions that controlled free [Ca 2+ ] i , we found that raising [Ca 2+ ] i from 100 to 600 nm produced similar increases in I Ks as did β-AR activation, and the effects appeared additive. Both β-AR activation and high [Ca 2+ ] i increased maximally activated tail I Ks , negatively shifted the voltage dependence of activation, and slowed deactivation kinetics. These data informed changes in our well-established mathematical model of the rabbit myocyte. In both AP-clamp experiments and simulations, I Ks recorded during a normal physiological Ca 2+ transient was similar to I Ks measured with [Ca 2+ ] i clamped at 500-600 nm. Thus, our study provides novel quantitative data as to how physiological [Ca 2+ ] i regulates I Ks amplitude and kinetics during the normal rabbit AP. Our results suggest that micromolar [Ca 2+ ] i , in the submembrane or

Regulation and quality in nuclear medicine 2 october 1998

International Nuclear Information System (INIS)

Kouchner, B.; Huriet, C.; Le Deaut, J.Y.

1999-01-01

The aim of this meeting is to examine how the regulations are liable to decrease the patient taking charge. The problem of the public information and opinion in the nuclear medicine domain is also presented. The nineteen presentations are proposed in 2 sessions. The first one deals with the state of the art of the nuclear medicine in France (techniques and regulations). The second one deals with the environment of the nuclear medicine (irradiation limits, public opinion, doctors and medicine quality). (A.L.B.)

The use of genre analysis in the design of electronic meeting systems

Directory of Open Access Journals (Sweden)

Pedro Antunes

2006-01-01

Full Text Available Introduction. Genre analysis is an approach to study communication patterns and thus it can be applied to the specific context of meetings. This research investigates the impact of genre analysis on the design of electronic meeting systems. Background. The primary goal of genre analysis is to understand how virtual communities use digital communication to collaborate. This knowledge is fundamental to inform IT design, particularly in areas where communication and informality are paramount. However, the research literature does not report any experiments where genre analysis has been used to inform electronic meeting system design. Problems. The paper tackles the following common problems found in current electronic meeting systems: (1 reduced organizational integration, neglecting many contextual cues and explaining factors necessary to make meeting outcomes usable within the organization; (2 lack of support to specific communities of users, stressing the dependency on a facilitator to configure and manage the technology; and (3 lack of support to meeting occurrences that span across long time periods. Conclusion. . The paper describes how genre analysis was used to develop electronic meeting systems for several organizations and meeting genres. It covers the complete design process, from genre elicitation to validation. The obtained results demonstrate that the genre approach produces electronic meeting systems focused on organizational integration, pre-configured to communities of users, supporting long-term usage and added organizational value.

Effective Emotions The Enactment of a Work Ethic in the Swedish Meeting Industry

Directory of Open Access Journals (Sweden)

Erika Andersson Cederholm

2010-09-01

Full Text Available The meeting industry – an encompassing term for services related to various kinds of professional meetings, from mega-conventions to the ordinary work meetings – is increasingly consolidated and legitimated as a specific sector in the service in-dustry. New professions such as meeting designers, meeting facilitators and meet-ing consultants are emerging, promoting new knowledge in this field. By focuss-ing on processes and social interaction, and highlighting emotional dimensions of meetings, these professions pave the way for new modes of conceptualising and practising professional relationships. The intangible, emotional and playful di-mensions of social interactions are promoted as effective means to achieve eco-nomic goals, thus highlighting a professional ideal that is here called “effective emotions”. The aim of this article is to show how the work ethic promoted by the meeting industry encourages new intersections, and tensions, between the ideali-sation of the tangible/measurable/rational on the one hand and the intangi-ble/emotional/magical on the other hand, and between working life and intimate spheres. Through a discourse analysis of a Swedish corporate meeting magazine, it is shown how the distinction between work and leisure is dissolved in this spe-cific work culture, and by this, it is discussed how the meeting profession acts as a normative regulator by reinforcing ideal ways of being and interacting with oth-ers. Creativity, personal growth, reflexivity and flexibility are enacted as idealised personal assets as well as moral imperatives in the discourse of the meeting pro-fession and through the practices of various meeting techniques, thus reinforcing not merely a professional ethic but cultural ideals of being as a person as well. It is also suggested that this reinforcement may, under certain circumstances, turn into its opposite and undermine the promoted ideals, thus pointing at the impor-tance to pinpoint the

When ideology meets conflict-related content: Influences on emotion generation and regulation.

Science.gov (United States)

Pliskin, Ruthie; Halperin, Eran; Bar-Tal, Daniel; Sheppes, Gal

2018-03-01

Do rightists and leftists experience information about suffering and harm with differing emotional intensities, depending on the identity of target depicted? Do they consequently choose differently how to regulate or cope with these emotions? Research has identified ideological differences in emotional processes, but it has yet to identify what types of content lead to ideological differences in emotional intensity or whether these content-dependent differences relate to differing preferences for engaging versus disengaging emotion-regulation strategies. We posited that right-left differences in experienced emotional intensity would be context-dependent, emerging mostly in response to depictions of harm to the outgroup, in accordance with the centrality of intergroup attitudes to ideological self-placement in conflict. Study 1 (N = 83) supported this hypothesis, with leftists (vs. rightists) experiencing outgroup harm (but not ingroup harm or conflict-irrelevant harm) with greater emotional intensity. Study 2 (N = 101), which replicated this finding, additionally examined whether behavioral differences in regulatory choice consequently emerge mostly regarding outgroup harm. We tested 2 competing hypotheses as to the nature of these differences: (a) the intensity hypothesis, positing that leftists (more than rightists) would regulate their intensified reactions to outgroup harm through disengagement-distraction (vs. engagement-reappraisal) due to a documented greater preference for disengaging coping strategies as intensity increases, and (b) the motivation hypothesis, positing that leftists (more than rightists) would prefer engagement-reappraisal (vs. disengagement-distraction), consistent with leftists' documented greater preference for intergroup empathy. Results exclusively supported the intensity hypothesis, and the significance of both studies is discussed. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Self-Tuning Speed Regulator for CVC Induction Motor Drive

DEFF Research Database (Denmark)

Bidstrup, N.; Rasmussen, Henrik; Knudsen, Torben

1994-01-01

A self-tuning speed regulator for a current vector controlled induction motor drive has been designed.......A self-tuning speed regulator for a current vector controlled induction motor drive has been designed....

Meeting of the ITER CTA Project Board

International Nuclear Information System (INIS)

2001-01-01

Full text: A preparatory meeting of the Co-ordinated Technical Activities (CTA) Project Board took place in Vienna on 16 July 2001. The Board Members of Canada, EU, Japan, RF and of the CTA International Team participated in the Meeting, which was chaired by Acad. E. Velikhov. The major item on the Meeting Agenda was the discussion of the scope of the CTA. In this discussion the following comments were expressed: One of the prime objectives during the CTA is to develop technical specifications for procurement of critical items (magnets, vacuum vessel, and buildings). It was noted that the discussions with potential suppliers should confirm manufacturing processes in details in order to explore possible schedule reduction strategies. Safety analysis and licensing preparation should proceed on all proposed sites up to the preferred site designation, to ensure the overall implementation schedule is minimized and to resolve major technical issues needed for licensing. Several R and D issues remain to be further developed during the CTA. Special attention should be given by the Participants to two areas: Diagnostics; Heating and Current Drive Systems. Arrangements for continuation of the ITER Physics Expert Groups activities should be provided. To this end a new framework, called International Tokamak Physics Activity, is being planned. The Board encouraged the Participants' Representatives in the Co-ordinating committee of this activity to support the preparation for urgent Topical Group Meetings. The Board agreed that the Design Authority will be invested in the International Team and that proposals for site specific design changes should be agreed upon by the International Team Leader before being studied in detail. The Meeting agreed on some arrangements which will remain from the EDA, namely the ITER EDA Council Office in Moscow as Office of the PB Chair, and the ITER Office located at the IAEA in Vienna as agreed by the IAEA. The Board recommended that effective

75 FR 42125 - Notice of Public Meeting, Dakotas Resource Advisory Council Meeting

Science.gov (United States)

2010-07-20

... Public Meeting, Dakotas Resource Advisory Council Meeting AGENCY: Bureau of Land Management, Interior..., Bureau of Land Management (BLM) Dakotas Resource Advisory Council (RAC) will meet as indicated below. DATES: The next regular meeting of the Dakotas Resource Advisory Council will be held on September 2...

78 FR 19461 - Multistakeholder Meetings To Develop Consumer Data Privacy Code of Conduct Concerning Mobile...

Science.gov (United States)

2013-04-01

.../privacy-multistakeholder-process-mobile-application-transparency , for the most current information. Place...-application-transparency , for the most current information. Other Information: The meetings are open to the... DEPARTMENT OF COMMERCE National Telecommunications and Information Administration Multistakeholder...

The role of nuclear power in meeting future energy demands

International Nuclear Information System (INIS)

Fuchs, K.

1977-01-01

Future energy demands and possibilities of meeting them are outlined. The current status and future developments of nuclear energetics all over the world and in the CMEA member states are discussed considering reactor safety, fission product releases, and thermal pollution of the environment

40 CFR 1043.50 - Approval of methods to meet Tier 1 retrofit NOX standards.

Science.gov (United States)

2010-07-01

... retrofit NOX standards. 1043.50 Section 1043.50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... SUBJECT TO THE MARPOL PROTOCOL § 1043.50 Approval of methods to meet Tier 1 retrofit NOX standards. Regulation 13 of Annex VI provides for certification of Approved Methods, which are retrofit procedures that...

Reversal thyristor-relay direct current commutator

International Nuclear Information System (INIS)

Ivanenko, A.I.

1982-01-01

A thyristor-relay commutator used for alteration of the leading magnetic field direction in experiments with polarized neutrons is described. The commutator flowsheet is presented. Thyristors, connected so as to allow the relay trigger operation mode, are used as controllable electronic relay. Two connected in series coils with the total inductance of the order of 0.28 H serve as the electronic relay load. The arc-free current commutation is effected at the moment of the minimal current across the load terminals, which allows to easily reverse the current up to 10 A at a volatage, v <= 150 V. The experience gained within a year of operation has shown that the commutator meets the requirements of reliability and tuning

Meetings in Academe: It's Time for an "EXTREME MEETING MAKEOVER!"

Science.gov (United States)

Berk, Ronald A.

2012-01-01

Meetings have a bad reputation with faculty. Rarely does one hear a positive word uttered about an upcoming or past meeting. That reputation has metastasized throughout higher education. The primary reason is because meetings can be major time wasters, accomplishing very little, often deteriorating into just another social event, or they may be…

76 FR 21779 - Notice of Public Meeting, Dakotas Resource Advisory Council Meeting

Science.gov (United States)

2011-04-18

... Public Meeting, Dakotas Resource Advisory Council Meeting AGENCY: Bureau of Land Management, Interior..., Bureau of Land Management (BLM) Dakotas Resource Advisory Council (RAC), will meet as indicated below. DATES: The next regular meeting of the Dakotas Resource Advisory Council will be held on May 11, 2011 in...

75 FR 15724 - Notice of Public Meeting, Dakotas Resource Advisory Council Meeting

Science.gov (United States)

2010-03-30

... Public Meeting, Dakotas Resource Advisory Council Meeting AGENCY: Bureau of Land Management, Interior..., Bureau of Land Management (BLM) Dakotas Resource Advisory Council (RAC) will meet as indicated below. DATES: The next regular meeting of the Dakotas Resource Advisory Council will be held on May 6, 2010, in...

76 FR 43705 - Notice of Public Meeting, Dakotas Resource Advisory Council Meeting

Science.gov (United States)

2011-07-21

... Public Meeting, Dakotas Resource Advisory Council Meeting AGENCY: Bureau of Land Management, Interior... Interior, Bureau of Land Management (BLM) Dakotas Resource Advisory Council (RAC), will meet as indicated below. DATES: The next regular meeting of the Dakotas Resource Advisory Council will be held on Aug. 17...

Current advances and strategies towards fully automated sample preparation for regulated LC-MS/MS bioanalysis.

Science.gov (United States)

Zheng, Naiyu; Jiang, Hao; Zeng, Jianing

2014-09-01

Robotic liquid handlers (RLHs) have been widely used in automated sample preparation for liquid chromatography-tandem mass spectrometry (LC-MS/MS) bioanalysis. Automated sample preparation for regulated bioanalysis offers significantly higher assay efficiency, better data quality and potential bioanalytical cost-savings. For RLHs that are used for regulated bioanalysis, there are additional requirements, including 21 CFR Part 11 compliance, software validation, system qualification, calibration verification and proper maintenance. This article reviews recent advances in automated sample preparation for regulated bioanalysis in the last 5 years. Specifically, it covers the following aspects: regulated bioanalysis requirements, recent advances in automation hardware and software development, sample extraction workflow simplification, strategies towards fully automated sample extraction, and best practices in automated sample preparation for regulated bioanalysis.

77 FR 22800 - Notice of Public Meeting, Dakotas Resource Advisory Council Meeting

Science.gov (United States)

2012-04-17

... Public Meeting, Dakotas Resource Advisory Council Meeting AGENCY: Bureau of Land Management, Interior..., Bureau of Land Management (BLM) Dakotas Resource Advisory Council (RAC) will meet as indicated below. DATES: The next regular meeting of the Dakotas RAC will be held on May 9, 2012, in Spearfish, SD. The...

My Most Memorable AAS Meeting-December 1957, Butler University, Indianapolis, Indiana

Science.gov (United States)

Edmondson, F. K.

1999-05-01

My attendance at AAS meetings began with the 46th meeting in September 1931 at the brand new Perkins Observatory. This was the first semester of my junior year at Indiana University. Professor Wilbur Cogshall, my astronomy professor, took me to the meeting, and paid my expenses for dormitory accommodations and meals. Hence, my attendance at AAS meetings covers a span of nearly 68 years. There have been so many "memorable" meetings that it is hard to pick just one. However, the 99th meeting in December 1957 at Butler University in Indianapolis, a joint meeting with the AAAS, is memorable because I was in a wheel chair and using crutches, following an injury to my right knee cap. I was a member of the AAAS Committee to select the "best paper" presented at the meeting to receive the Newcomb Cleveland Prize, and Martin Schwarzschild's first report of results from Project Stratoscope was on the program. I showed up at the Committee meeting in my wheel chair, and nominated Martin's paper for the "best paper" award. The Committee asked a lot of questions and then approved the paper by a unanimous vote. The wheel chair and crutches obviously played a role in convincing the Committee that I had strong feelings about the merits of Martin's paper. Allan Sandage was the Warner Prize Lecturer, and reported on the current status of his revision of the cosmic distance scale. Hubble's 1936 distances needed to be increased by a factor of five to ten.

1st International Experts’ Meeting on Agitation: Conclusions Regarding the Current and Ideal Management Paradigm of Agitation

Directory of Open Access Journals (Sweden)

José Martínez-Raga

2018-02-01

Full Text Available Agitation is a heterogeneous concept without a uniformly accepted definition, however, it is generally considered as a state of cognitive and motor hyperactivity characterized by excessive or inappropriate motor or verbal activity with marked emotional arousal. Not only the definition but also other aspects of agitated patients’ care are still unsolved and need consensus and improvement. To help the discussion about agitation among experts and improve the identification, management, and treatment of agitation, the 1st International Experts’ Meeting on Agitation was held in October 2016 in Madrid. It was attended by 20 experts from Europe and Latin America with broad experience in the clinical management of agitated patients. The present document summarizes the key conclusions of this meeting and highlights the need for an updated protocol of agitation management and treatment, the promotion of education and training among healthcare professionals to improve the care of these patients and the necessity to generate clinical data of agitated episodes.