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  1. Novel synthetic Medea selfish genetic elements drive population replacement in Drosophila; a theoretical exploration of Medea-dependent population suppression.

    Science.gov (United States)

    Akbari, Omar S; Chen, Chun-Hong; Marshall, John M; Huang, Haixia; Antoshechkin, Igor; Hay, Bruce A

    2014-12-19

    Insects act as vectors for diseases of plants, animals, and humans. Replacement of wild insect populations with genetically modified individuals unable to transmit disease provides a potentially self-perpetuating method of disease prevention. Population replacement requires a gene drive mechanism in order to spread linked genes mediating disease refractoriness through wild populations. We previously reported the creation of synthetic Medea selfish genetic elements able to drive population replacement in Drosophila. These elements use microRNA-mediated silencing of myd88, a maternally expressed gene required for embryonic dorso-ventral pattern formation, coupled with early zygotic expression of a rescuing transgene, to bring about gene drive. Medea elements that work through additional mechanisms are needed in order to be able to carry out cycles of population replacement and/or remove existing transgenes from the population, using second-generation elements that spread while driving first-generation elements out of the population. Here we report the synthesis and population genetic behavior of two new synthetic Medea elements that drive population replacement through manipulation of signaling pathways involved in cellular blastoderm formation or Notch signaling, demonstrating that in Drosophila Medea elements can be generated through manipulation of diverse signaling pathways. We also describe the mRNA and small RNA changes in ovaries and early embryos associated from Medea-bearing females. Finally, we use modeling to illustrate how Medea elements carrying genes that result in diapause-dependent female lethality could be used to bring about population suppression.

  2. Novel Synthetic Medea selfish genetic elements drive population replacement in Drosophila, and a theoretical exploration of Medea-dependent population suppression

    Science.gov (United States)

    Akbari, Omar S.; Chen, Chun-Hong; Marshall, John M.; Huang, Haixia; Antoshechkin, Igor; Hay, Bruce A.

    2013-01-01

    Insects act as vectors for diseases of plants, animals and humans. Replacement of wild insect populations with genetically modified individuals unable to transmit disease provides a potentially self-perpetuating method of disease prevention. Population replacement requires a gene drive mechanism in order to spread linked genes mediating disease refractoriness through wild populations. We previously reported the creation of synthetic Medea selfish genetic elements able to drive population replacement in Drosophila. These elements use microRNA-mediated silencing of myd88, a maternally expressed gene required for embryonic dorso-ventral pattern formation, coupled with early zygotic expression of a rescuing transgene, to bring about gene drive. Medea elements that work through additional mechanisms are needed in order to be able to carry out cycles of population replacement and/or remove existing transgenes from the population, using second-generation elements that spread while driving first-generation elements out of the population. Here we report the synthesis and population genetic behavior of two new synthetic Medea elements that drive population replacement through manipulation of signaling pathways involved in cellular blastoderm formation or Notch signaling, demonstrating that in Drosophila Medea elements can be generated through manipulation of diverse signaling pathways. We also describe the mRNA and small RNA changes in ovaries and early embryos associated from Medea-bearing females. Finally, we use modeling to illustrate how Medea elements carrying genes that result in diapause-dependent female lethality could be used to bring about population suppression. PMID:23654248

  3. Predictable Medea

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    Elisabetta Bertolino

    2010-01-01

    Full Text Available By focusing on the tragedy of the 'unpredictable' infanticide perpetrated by Medea, the paper speculates on the possibility of a non-violent ontological subjectivity for women victims of gendered violence and whether it is possible to respond to violent actions in non-violent ways; it argues that Medea did not act in an unpredictable way, rather through the very predictable subject of resentment and violence. 'Medea' represents the story of all of us who require justice as retribution against any wrong. The presupposition is that the empowered female subjectivity of women’s rights contains the same desire of mastering others of the masculine current legal and philosophical subject. The subject of women’s rights is grounded on the emotions of resentment and retribution and refuses the categories of the private by appropriating those of the righteous, masculine and public subject. The essay opposes the essentialised stereotypes of the feminine and the maternal with an ontological approach of people as singular, corporeal, vulnerable and dependent. There is therefore an emphasis on the excluded categories of the private. Forgiveness is taken into account as a category of the private and a possibility of responding to violence with newness. A violent act is seen in relations to the community of human beings rather than through an isolated setting as in the case of the individual of human rights. In this context, forgiveness allows to risk again and being with. The result is also a rethinking of feminist actions, feminine subjectivity and of the maternal. Overall the paper opens up the Arendtian category of action and forgiveness and the Cavarerian unique and corporeal ontology of the selfhood beyond gendered stereotypes.

  4. La Medea de Lars von Trier

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    Iratxe Fresneda Delgado

    2013-04-01

    Full Text Available El presente artículo analiza el modo en el que Lars von Trier recrea para el cine el estereotipo de Medea. Mediante el análisis fílmico de la película y apoyándose en los estudios culturales, el texto se interroga acerca de la importancia y el poder potencial del cine a la hora recuperar el antiguo mito y demostrar su vigencia. El análisis amplía horizontes para la compresión de los mecanismos que articulan el entramado de significados de la película, donde Von Trier aporta una nueva visión del arquetipo de Medea uniéndola, a la tradición pictórica del Romanticismo. Una influencia que habita en las posteriores obras del director danés, donde el paisaje, la naturaleza, se erige en elemento catalizador de las pulsiones humanas, en su cómplice y testigo.This paper explores the way that Lars von Trier’s film recreates the stereotype of Medea. Using film analysis and based on cultural studies the article asks about the importance and potential power of cinema to recover the ancient myth and show their effects. The analysis expands horizons for the understanding of the mechanisms that link the network of meanings of the film, where the author offers a new vision of Medea's archetype attaching it to the pictorial tradition tied to the Romanticism. An influence that can be seen in the later works of Lars von Trier, where the landscape, the nature, stands as a catalyst of human drives, as his accomplice and witness.

  5. Medea in the past and in the present: (Reconstructing the identity of a woman and a foreigner in the novel Medea by Christa Wolf

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    Stevanović Lada

    2010-01-01

    Full Text Available One of the most shocking, the most difficult to understand and at the same time the most inspiring tragedy from the Greek antiquity is Euripeides' Medea. This drama has a rich and a long history of adaptations that have always represented an interface between the ancient text on the one hand, and the author's reading on the other, which always depended on cultural and political context of the period that influenced the perspective of the author. Most of these adaptations belong to theatrical production. However my interest in this paper is not oriented towards theatre, but towards literature, a novel Medea: A Modern Retelling by Christa Wolf. First part of the paper deals with the reconstruction of the ancient context and meaning of this drama in the antiquity from the perspective of contemporary study of classics, while the second part is devoted to the questions of Wolf's adaptation: the ways in which Christa Wolf rewrites Medea, tracing of Wolf's reasons to approach the text in such a way, the main relation of Wolf's version to former version(s, and intellectual and social climate in which Wolf's Medea was created. The focus of the research will be on the reading of the construction of the Other, of gender and gender roles, also through the analysis of their transgression - in the Greek antiquity when Euripides drama was staged, as well in the Germen (European context of the end of the twentieth century in which Medea was rewritten by Christa Wolf.

  6. Medea genes, handedness and other traits

    Science.gov (United States)

    Hatfield, Jeffrey

    2015-01-01

    Medea factors or genes are maternal-effects mechanisms, found in many species, in which the mother's body selectively kills embryos of a certain genotype.Humans have a similar genetic mechanism, the gene RHD which produces Rh-factor involved in blood type.Recently I proposed that RHD acts as a maternal-effects gene that determines handedness (i.e., right handed or non-right handed) in individuals of our species. Here, I argue that RHD functions as a Medea gene as well.The handedness gene (and also RHD itself in some cases) has been implicated in autism spectrum disorders (ASD), bipolar disorder, cerebral laterality (i.e., right-brained or left-brained speech laterality), hair-whorl rotation, schizophrenia, sexual orientation, and speech dyslexia.Identifying the gene or genes that determine handedness or cerebral laterality may help uncover the mechanisms underlying these behavioral phenotypes in our species.A relatively simple test of the handedness hypothesis has been proposed:In a sample of humans for whom handedness has been evaluated, we would need to genotype for RHD by determining whether Rh+ individuals have one or two copies of the dominant allele. If RHD and perhaps also an interaction with RHCE are involved in sexual orientation, it explains how selection could favor a gene or genes which cause some people to become non-heterosexual.The literature on Medea genes provides the explanation:A Medea allele must increase in frequency, sometimes to fixation (i.e., 100% frequency) even if it reduces fecundity (e.g., birth rate).In addition, treatment for RHD maternal-fetal genotype incompatibility, which allows more fetuses to survive to term now, may be one explanation for why ASD appears to be increasing in frequency in some populations, if RHD is indeed the handedness gene, although many other mechanisms have also been suggested. One wonders if bipolar disorder and the other alternative phenotypes are also increasing in frequency.

  7. Magijos ritualas Senekos Medėjoje | Magic Ritual in Seneca’s Medea

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    Jovita Dikmonienė

    2013-12-01

    Full Text Available Magic Ritual in Seneca’s Medea Jovita Dikmonienė Summary The present article deals with the magic ritual in Seneca’s Medea. Seneca, following Ovid’s Metamorphoses, created in the tragedy a witchcraft scene which describes magic numbers, herbs, and rituals dedicated to Hecate. Unlike Ovid, Seneca focuses on rituals involving snakes, conjuring up the dead, and supernatural performative utterances, and emphasises the feeling of anger, which inspired Medea to practise infernal magic. In magic, Romans gave particular importance to the number “three” and the numbers that can be divided by three. Seneca also mentions these numbers. During the performance of the ritual by Medea, Hecate barks three times, a dragon with a trident tongue appears, and tripods play during the ritual. Medea sends to Creusa not two, as in Euripides’ tragedy, but three poisoned gifts: a robe, a necklace, and a crown. Seneca’s Medea makes a wreath to Hecate from nine snakes. Magical, hallucinogenic herbs play an important role in magic. Seneca, like Ovid in his Metamorphoses, describes Medea’s ritual whereby she prepares a magical blend of herbs to poison Creusa. Prometheus’ grass used by Medea is probably mandrake. However, Seneca, like Ovid, does not provide the exact names of the herbs used in magic. Some researchers argue that Seneca described the magic ritual in order to highlight Medea’s desire to control the environment. According to the author of the present article, this claim is only partially true. Magic was necessary for Medea not only to control the environment, but also to control herself. The magic ritual helped her to prepare herself for revenge by transforming her consciousness. With the help of magic her sorrow and pity were transformed into aggression, she overcame her fear and prepared herself to kill her children. Medea’s ritual can be described as the magic of the fight, because it allowed her to transform her consciousness into the

  8. The otherness of a Barbarianess: Euripides’ Medea and Medea by Velimir Lukić

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    Šijaković Đurđina

    2014-01-01

    Full Text Available Belonging to a social community, a nation, a culture or a religion, can be expressed by stressing differences and borders between us and others, between our collective self and their otherness. Achievements of classical Greek culture for us are primarily bound to the polis, city-state, but classical Greek literature gives quite significance to the definition of universal Greek identity by creating the figure of a barbarian on the opposite side. This contrast between Greeks and barbarians, not noticeable in the literature of archaic period, grows more and more important (while the notion of the word barbarian becomes more pejorative with gradual intrusion of Persian domination over west area of Asia Minor from the middle of VI BC and with successful resistance of many Greek states in the first half of V BC. The basic feature that defines the notion βάρβαρος is a lack of moral responsibility indispensable for enjoying (but active enjoying, applying, engaging in, practicing political freedom. Moral responsibility and political freedom are closely connected through λόγος - which is ability to reason and also ability to speak (in Greek. The image of barbarian is further elaborated with features of cruelty and excessiveness of all kinds (especially when it comes to somatic pleasures, i.e. a lack of moderation, so essential to Greeks. On the other hand, “to be Greek” meant: to be a citizen of a Greek polis having full civic rights. This further means: exclusively men. Otherness in being a barbarian, hence, goes hand in hand with Otherness of a woman in ancient Greek world. This polarity also includes the tension between πόλις and οἶκος, i.e. the tension between public-political and private-family life. Bearing this dichotomy in mind, I am re-reading two theatric plays: Euripides’ (cca 480-406 BC tragedy Medea and radio-drama Medea of Serbian writer Velimir Lukić (1936-1937, one of many literary and art-works inspired by

  9. Medea's Nuptial Gifts: Myth and Biomedical Reality.

    Science.gov (United States)

    Diamandopoulos, Athanasios

    2016-12-01

    In all art forms, Medea is mainly represented as the tragic witch from Colchis (contemporary Georgia), who slaughtered her sons and killed her erotic rival Glauke and her father, King Creon of Corinth, by offering an elaborate poisonous nuptial garment. Euripides described the victims' symptoms as a sudden extreme inflammation, leading anyone coming into contact with the garment to death. In other version, the inflammation is described as pure fire. The symptoms resemble what current medical knowledge describes as an immune contact sensitivity reaction. The passages with medical interest from the opera based on this tragedy are presented in the original musical form as well as some similar film and theater scenes. Magnified images of harmful insect's Medea's nuptial gifts are shown and their action is discussed.

  10. Medea: Aggression im Dienste weiblicher Subjektivierung Medea: How aggression works for female subjugation

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    Monika Gsell

    2003-11-01

    Full Text Available Aggression wurde in der Geschlechterforschung bisher meist nicht nur unter negativen Vorzeichen – nämlich als zerstörerische und fehlgeleitete Kraft – thematisiert und mit Gewalt in eins gesetzt, sondern darüberhinaus fast ausschließlich mit Männlichkeit konnotiert. Nur langsam setzt sich demgegenüber die Einsicht durch, dass Aggression zunächst einmal eine grundsätzlich positive Kraft ist, derer es zur Subjektivierung und Erlangung von Selbstbestimmung bedarf. Damit scheint nun auch eine fruchtbare Auseinandersetzung mit Weiblichkeit und Aggression möglich geworden zu sein. Ein lehrreicher Beitrag dazu ist Roxana Hidalgos Medea-Studie, gerade weil sie die eigentlich heiklen Fragen weder stellt noch beantwortet.So far, gender studies have tended to thematise aggression not only as a destructive, misdirected force, but one that is regarded almost without exception as masculine. Slowly, though, understanding is growing that aggresion should be viewed in principle as a positive force that is vital for the process of gaining subjectivity and self-determination. This insight seems to have opened the potential to discuss femininity and aggression in new and fruitful ways. Roxana Hidalgos’s study of Medea is an instructive contribution to this discussion – especially/above all because the author neither asks nor answers the really tricky questions.

  11. A selfish gene chastened: Tribolium castaneum Medea M4 is silenced by a complementary gene.

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    Thomson, M Scott

    2014-04-01

    Maternal-effect dominant embryonic arrest (Medea) of Tribolium castaneum are autosomal factors that act maternally to cause the death of any progeny that do not inherit them. This selfish behavior is thought to result from a maternally expressed poison and zygotically expressed antidote. Medea factors and the hybrid incompatibility factor, H, have a negative interaction consistent with complementary genes of the Dobzhansky-Muller model for post-zygotic isolation. This negative interaction may result from H suppression of Medea zygotic antidote, leaving zygotes incompletely protected from maternal poison. I report here a test of the hypothesis that H also suppresses the Medea maternal poison. Viable F1 females were generated from a cross of Medea M4 strain males to H strain females. These females, heterozygous for both M4 and H, failed to express M4 maternal lethal activity when crossed to their male sibs. Transmission of non-M4 homologues from these females was confirmed using a dominant transgenic enhanced green fluorescent protein eye color marker, tightly linked in cis to M4. M4 beetles, lacking H, were selected from the F2 population. Female descendants of these clearly expressed M4 maternal lethal activity, indicating restoration of this activity after H was segregated away. I conclude that H, or a factor tightly linked to H, suppresses Medea M4 maternal poison.

  12. Medea by Dane Zajc

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    Kristina Tomc

    2006-07-01

    Full Text Available The article discusses the play Medea (Medeja by the Slovene poet Dane Zajc. Its focus is on character analysis, since this might provide additional insights into Euripides’ tragedy for the high-school students preparing to take the final examination (matura in Latin. The complex structure of Zajc’s play corresponds to the author’s concept of time, which is not linear but spirals in an “eternal returning without return”, a punishment worse than death for the characters.

  13. The maternal-effect, selfish genetic element Medea is associated with a composite Tc1 transposon.

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    Lorenzen, Marcé D; Gnirke, Andreas; Margolis, Jonathan; Garnes, Jeffrey; Campbell, Margie; Stuart, Jeffrey J; Aggarwal, Rajat; Richards, Stephen; Park, Yoonseong; Beeman, Richard W

    2008-07-22

    Maternal-Effect Dominant Embryonic Arrest ("Medea") factors are selfish nuclear elements that combine maternal-lethal and zygotic-rescue activities to gain a postzygotic survival advantage. We show that Medea(1) activity in Tribolium castaneum is associated with a composite Tc1 transposon inserted just downstream of the neurotransmitter reuptake symporter bloated tubules (blot), whose Drosophila ortholog has both maternal and zygotic functions. The 21.5-kb insertion contains defective copies of elongation initiation factor-3, ATP synthase subunit C, and an RNaseD-related gene, as well as a potentially intact copy of a prokaryotic DUF1703 gene. Sequence comparisons suggest that the current distribution of Medea(1) reflects global emanation after a single transpositional event in recent evolutionary time. The Medea system in Tribolium represents an unusual type of intragenomic conflict and could provide a useful vehicle for driving desirable genes into populations.

  14. Antonin Artaud y la Medea de Séneca

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    Juan Carlos Sánchez León

    1999-01-01

    Full Text Available Este artículo analiza la influencia de las tragedias de Séneca en la filosofía teatral que Antonin Artaud desarrolla entre 1932 y 1936. En su reseña de una adaptación española de Medea representa en México en 1936 (publicada en el diario El Nacional, Artaud explica algunos conceptos teóricos de los manifiestos del «Teatro de la Crueldad» (1932-1933, especialmente la «técnica de la tragedia».This article analyses the influence of Séneca's tragedles on the philosophy of drama developed by Antonin Artaud between 1932 and 1936. In his review of a Spanish adaptation of Medea performed in México in 1936 (published in the Journal E\\ Nacional, Artaud explains some theoretical concepts appeared in the manifestos of the «Theatre of Cruelty» (1932- 1933, specially the «techñique of tragedy».

  15. The MEDEA/JASON remotely operated vehicle system

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    Ballard, Robert D.

    1993-08-01

    The remotely operated vehicle (ROV) system MEDEA/JASON has been under development for the last decade. Adter a number of engineering test cruises, including the discovery of the R.M.S. Titanic and the German Battleship Bismarck, this ROV system is now being implemented in oceanographic investigations. This paper explains its development history and its unique ability to carry out a broad range of scientific research.

  16. Euripides' Medea: a psychodynamic model of severe divorce pathology.

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    Jacobs, J W

    1988-04-01

    Analysis of Euripides' play, Medea, and a divorcing family suggests that divorce between a narcissistically scarred, embittered, dependent woman and a pathologically narcissistic, devaluing man may lead to the mother's attempt to sever father-child contact as a means of revenging the injury inflicted on her by the loss of a selfobject, her hero-husband.

  17. The 3R-WL working level survey meter

    International Nuclear Information System (INIS)

    Schiager, K.J.

    1977-01-01

    The design and operation of a direct-reading sampler for airborne radon progeny are described. The instrument was designed for use by ventilation personnel in uranium mines and is small, rugged, light-weight and easily carried and operated. Direct readout of the radon progeny concentration in units of working levels, in the range 0.01 - 10 WL, is accomplished by counting the alpha particles from 218 Po and 214 Po with a single detector and two energy discrimination channels. Unique features include a fixed-volume, gravity-operated pump requiring no power source and minimal calibration; automatic delay, counting and display sequencing; capacity for more than 50 samples on a single roll of membrane filter; and provisions for recording all data directly on the filter tape. For the prototype as built, calibration against the 2-count alpha spectroscopy method of measuring WL indicated an average error of less than 1% in the range from 0.25 to 25 WL. However, the standard deviation of measurements made with the 3R-WL meter increased from 7% above 10 WL to 71% at 0.25 WL. Sources of error and variability are analyzed and suggestions for improving the precision of the measurements are included. (author)

  18. A tidally interacting disk in the young triple system WL 20?

    OpenAIRE

    Barsony, Mary; Greene, Thomas P.; Blake, Geoffrey A.

    2002-01-01

    We present high-resolution λ = 2.7 mm imaging of the close triple pre-main-sequence system WL 20. Compact dust emission with integrated flux density of 12.9 ± 1.3 mJy is associated with two components of the triple system, WL 20W and WL 20S. No emission above a 3 σ level of 3.9 mJy is detected toward the third component, WL 20E, which lies 3."17 (400 AU) due east in projection from its neighbors. A possibly warped structure of ~0.1 M_☉ and ≤3."2 extent encompasses WL 20W and WL 20S, which hav...

  19. La transfiguración histórica del mito de Medea: de Eurípides a Christa Wolf

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    Bernardita Bolumburu Perl

    2009-10-01

    Full Text Available El presente ensayo tiene como objeto de estudio un personaje de la mitología y la Antigüedad Clásica llamado Medea, el cual es examinado a la luz de miradas actuales que ofrecen nuevas aristas de significación en virtud de diversos registros históricos. Este personaje, reconocido en la cultura occidental a través de la tragedia de Eurípides como la mujer que asesinó a sus hijos en venganza contra su esposo, alberga versiones mitológicas que difieren del retrato creado por el dramaturgo griego. El objetivo es, por lo tanto, exponer esa otra historia de Medea a partir de la obra de la escritora alemana Christa Wolf titulada Medea. Voces (1998. Asimismo, se examinarán algunas adaptaciones contemporáneas de esta figura (en literatura, cine, pintura, escultura y ópera que reconstruyen la obra de Eurípides.

  20. WL 17: A Young Embedded Transition Disk

    OpenAIRE

    Sheehan, Patrick D.; Eisner, Josh A.

    2017-01-01

    We present the highest spatial resolution ALMA observations to date of the Class I protostar WL 17 in the $\\rho$ Ophiuchus L1688 molecular cloud complex, which show that it has a 12 AU hole in the center of its disk. We consider whether WL 17 is actually a Class II disk being extincted by foreground material, but find that such models do not provide a good fit to the broadband SED and also require such high extinction that it would presumably arise from dense material close to the source such...

  1. Properties and natural occurrence of maternal-effect selfish genes ('Medea' factors) in the red flour beetle, tribolium castaneum

    Science.gov (United States)

    Beeman; Friesen

    1999-05-01

    Maternally acting selfish genes, termed 'Medea' factors, were found to be widespread in wild populations of Tribolium castaneum collected in Europe, North and South America, Africa and south-east Asia, but were rare or absent in populations from Australia and the Indian subcontinent. We detected at least four distinct genetic loci in at least two different linkage groups that exhibit the Medea pattern of differential mortality of genotypes within maternal families. Although each M factor tested had similar properties of maternal lethality to larvae and zygotic self-rescue, M factors representing distinct loci did not show cross-rescue. Alleles at two of these loci, M1 and M4, were by far the most prevalent, M4 being the predominant type. M2 and M3 were each found only once, in Pakistan and Japan, respectively. Although M1 could be genetically segregated from M4 and maintained as a purified stock, the M1 factor invariably co-occurred with M4 in field populations, whereas M4 usually occurred in the absence of other Medea factors. The dominant maternal lethal action of M1 could be selectively inactivated (reverted) by gene-knockout gamma irradiation with retention of zygotic rescue activity.

  2. Properties and natural occurrence of maternal-effect selfish genes ('Medea' factors) in the red flour beetle, Tribolium castaneum

    International Nuclear Information System (INIS)

    Beeman, R.W.; Friesen, K.S.

    1999-01-01

    Maternally acting selfish genes, termed 'Medea' factors, were found to be widespread in wild populations of Tribolium castaneum collected in Europe, North and South America, Africa and south-east Asia, but were rare or absent in populations from Australia and the Indian subcontinent. We detected at least four distinct genetic loci in at least two different linkage groups that exhibit the Medea pattern of differential mortality of genotypes within maternal families. Although each M factor tested had similar properties of maternal lethality to larvae and zygotic self-rescue, M factors representing distinct loci did not show cross-rescue. Alleles at two of these loci, M 1 and M 4 , were by far the most prevalent, M 4 being the predominant type. M 2 and M 3 were each found only once, in Pakistan and Japan, respectively. Although M 1 could be genetically segregated from M 4 and maintained as a purified stock, the M 1 factor invariably co-occurred with M 4 in field populations, whereas M 4 usually occurred in the absence of other Medea factors. The dominant maternal lethal action of M 1 could be selectively inactivated (reverted) by gene-knockout gamma irradiation with retention of zygotic rescue activity. (author)

  3. Mito, magia e iconografia. I sortilegi di Medea nelle stampe di Giovanni Antonio Rusconi per le Trasformationi di Lodovico Dolce / Myth, magic and iconography. Medea’s sorceries in the woodcuts by Giovanni Antonio Rusconi for Lodovico Dolce’s “Trasformationi”

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    Giuseppe Capriotti

    2013-05-01

    Full Text Available Anche se dopo la famosa tragedia di Euripide fonti letterarie e iconografiche rappresentano Medea principalmente come madre infanticida, la Medea delle Metamorfosi di Ovidio è soprattutto una potente maga: una sapiente conoscitrice di erbe, con cui sa preparare efficaci pozioni magiche, e un’abile manipolatrice diricette prodigiose, che si attivano grazie all’aiuto di divinità infere, invocate con formule vocali nei suoi riti notturni. Allo stesso modo, nelle xilografie che decorano le edizioni rinascimentali delle Metamorfosi, in particolare in quelle di Giovanni Antonio Rusconi per le Trasformationi di Lodovico Dolce, Medea è raffigurata soprattutto come una avvenente maga, che compie i suoi sortilegi per amore o per vendetta. Specialmente nella stampa con Il ringiovanimento di Esone, Rusconi mescola i connotati della maga rinascimentale e quelli della strega nordica: Medea è ancora un’attraente e giovane donna, ma compie oramai operazioni magiche al limite della fattucchieria.   Even though after the famous tragedy of Euripides literary and iconographic sources represent Medea mainly as infanticide mother, the Medea of the Ovid’s Metamorphoses is above all a powerful sorceress: a wise expert of grasses, by which she prepares effective magic potions, and a skilled manipulator of prodigious recipes, that she activates thanks to the help of hellish divinities, invoked with vocal formulas in her nighttime rites. In the same way, in the woodcuts that decorate the Renaissance editions of the Metamorphoses, particularly in those of Giovanni Antonio Rusconi for the Lodovico Dolce’s Trasformationi, Medea is represented above all as a good-looking sorceress, that executes her sorceries for love or for revenge. Especially in the woodcut with The rejuvenation of Esone, Rusconi combines the characteristics of the Renaissance sorceress with those of the Northern witch: Medea is still an attractive and young woman, but she carry out, by now

  4. MEDEA, Steady-State Pressure and Temperature Distribution in He H2O Steam Generator

    International Nuclear Information System (INIS)

    Hansen, Ulf

    1976-01-01

    1 - Nature of physical problem solved: MEDEA calculates the time-independent pressure and temperature distribution in a helium-water steam generator. The changing material properties of the fluids with pressure and temperature are treated exactly. The steam generator may consist of economizer, evaporator, superheater and reheater in variable flow patterns. In case of reheating the high-pressure turbine is taken into account. The main control circuits influencing the behaviour of the system are simulated. These are water spraying of the hot steam, load-dependent control of steam pressure at the HP-turbine inlet and valves before the LP-turbine to ensure constant pressure in the reheater section. Investigations of hydrodynamic flow stability in single tubes can be performed. 2 - Method of solution: The steam generator is calculated as a 1-dimensional model, (i.e. all parallel tubes working under equal conditions) and is divided into small heat exchanger elements with helium and water in ideal parallel or counter flow. The material and thermodynamic properties are kept constant within one element. The calculations start at the cold end of the steam generator and proceed stepwise along the water flow pattern to produce pressure and temperature distributions of helium and water. The gas outlet temperature is changed until convergence is reached with a continuous temperature profile on the gas side. MEDEA chooses the iteration scheme according to flow pattern and other special arrangements in the steam generator. The hydrodynamic stability is calculated for a single tube assuming that all tubes are exposed to the same gas temperature profile and changing the water flow in a single tube will not influence the conditions on the gas side. Varying the water flow by keeping gas temperature constant and repeating the steam generator calculations yield pressure drop and steam temperature as a function of flow rate. 3 - Restrictions on the complexity of the problem: Maximum

  5. Selection of a radon level corresponding to 0.02 WL

    International Nuclear Information System (INIS)

    Haywood, L.R.

    1980-01-01

    The Atomic Energy Control Board requires that the concentration of radon daughters in occupied structures in communities associated with nuclear facilities be less than 0.02 working level. The AECB has been interested in using measurements of radon concentration rather than of working level for compliance at 0.02 WL. It has been found, however, that there is no radon concentration which corresponds to 0.02 WL over a typical range of field conditions. This is principally due to the range of physical characteristics of structures, heating methods, living habits and of outdoor temperatures that may be encountered. A radon level of 2.4 pCi/l would indicate 95 percent of the instances at the three towns studied when working level exceeded 0.02

  6. Degradation of ethyl mercaptan and its major intermediate diethyl disulfide by Pseudomonas sp. strain WL2.

    Science.gov (United States)

    Wang, Xiangqian; Wu, Chao; Liu, Nan; Li, Sujing; Li, Wei; Chen, Jianmeng; Chen, Dongzhi

    2015-04-01

    A Pseudomonas sp. strain WL2 that is able to efficiently metabolize ethyl mercaptan (EM) into diethyl disulfide (DEDS) through enzymatic oxidation was isolated from the activated sludge of a pharmaceutical wastewater plant. One hundred percent removal of 113.5 mg L(-1) EM and 110.3 mg L(-1) DEDS were obtained within 14 and 32 h, respectively. A putative EM degradation pathway that involved the catabolism via DEDS was proposed, which indicated DEDS were further mineralized into carbon dioxide (CO2), bacterial cells, and sulfate (SO4 (2-)) through the transformation of element sulfur and ethyl aldehyde. Degradation kinetics for EM and DEDS with different initial concentrations by strain WL2 were evaluated using Haldane-Andrews model with maximum specific degradation rates of 3.13 and 1.33 g g(-1) h(-1), respectively, and maximum degradation rate constants of 0.522 and 0.175 h(-1) using pseudo-first-order kinetic model were obtained. Results obtained that aerobic degradation of EM by strain WL2 was more efficient than those from previous studies. Substrate range studies of strain WL2 demonstrated its ability to degrade several mercaptans, disulfides, aldehydes, and methanol. All the results obtained highlight the potential of strain WL2 for the use in the biodegradation of volatile organic sulfur compounds (VOSCs).

  7. Production of Xylitol from D-Xylose by Overexpression of Xylose Reductase in Osmotolerant Yeast Candida glycerinogenes WL2002-5.

    Science.gov (United States)

    Zhang, Cheng; Zong, Hong; Zhuge, Bin; Lu, Xinyao; Fang, Huiying; Zhuge, Jian

    2015-07-01

    Efficient bioconversion of D-xylose into various biochemicals is critical for the developing lignocelluloses application. In this study, we compared D-xylose utilization in Candida glycerinogenes WL2002-5 transformants expressing xylose reductase (XYL1) in D-xylose metabolism. C. glycerinogenes WL2002-5 expressing XYL1 from Schefferomyces stipitis can produce xylitol. Xylitol production by the recombinant strains was evaluated using a xylitol fermentation medium with glucose as a co-substrate. As glucose was found to be an insufficient co-substrate, various carbon sources were screened for efficient cofactor regeneration, and glycerol was found to be the best co-substrate. The effects of glycerol on the xylitol production rate by a xylose reductase gene (XYL1)-overexpressed mutant of C. glycerinogenes WL2002-5 were investigated. The XYL1-overexpressed mutant produced xylitol from D-xylose using glycerol as a co-substrate for cell growth and NAD (P) H regeneration: 100 g/L D-xylose was completely converted into xylitol when at least 20 g/L glycerol was used as a co-substrate. XYL1 overexpressed mutant grown on glycerol as co-substrate accumulated 2.1-fold increased xylitol concentration over those cells grown on glucose as co-substrate. XYL1 overexpressed mutant produced xylitol with a volumetric productivity of 0.83 g/L/h, and a xylitol yield of 98 % xylose. Recombinant yeast strains obtained in this study are promising candidates for xylitol production. This is the first report of XYL1 gene overexpression of C. glycerinogenes WL2002-5 for enhancing the efficiency of xylitol production.

  8. MEDEA: A multi element detector array for gamma ray and light charged particle detection at the LNS-Catania

    International Nuclear Information System (INIS)

    Migneco, E.; Agodi, C.; Alba, R.; Coniglione, R.; Del Zoppo, A.; Finocchiaro, P.; Maiolino, C.; Piattelli, P.; Raia, G.; Sapienza, P.; Bellia, G.

    1992-01-01

    A 4π highly granular Multi Element Detector Array (MEDEA) for γ-rays and light charged particles is described. Its basic configuration consists of 180 barium fluoride scintillator crystals, arranged in the shape of a ball, plus a forward angle wall of 120 phoswich detectors. The inner radius of the ball (22 cm) and the distance of the wall from the target (55 cm) allow the placement of other detectors in the inner volume. The whole detection system operates under vacuum inside a large scattering chamber. Dedicated electronics has been designed and realized. It includes a powerful hardware second level trigger and preanalysis system, which allows on-line event selection, and a modular VME-bus based data acquisition system. In-beam performances of the system are also described. (orig.)

  9. Accuracy of single count methods of WL determination for open-pit uranium mines

    International Nuclear Information System (INIS)

    Solomon, S.B.; Kennedy, K. N.

    1983-01-01

    A study of single count methods of WL determination was made using a database respresentative of Australian open pit uranium mine conditions. The aim of the study was to check the existence of the optimum time delay coresponding to the Rolle method, to determine the accuracy of the conversion factor for Australian conditions and to examine any systematic use of data bases of representative radon daughter concentration

  10. Versiones y revisiones cinematográficas de un mito clásico : las Medeas de Pasolini, Dassin, von Trier y Ripstein (1969-2000

    Directory of Open Access Journals (Sweden)

    María del Carmen del Barrio Mendoza

    2011-01-01

    Full Text Available El presente trabajo plantea un profundo análisis de cuatro de las adaptaciones cinematográficas del mito de Medea que se ha considerado tienen una mayor trascendencia, ya sea por su manera innovadora de reinterpretar el mito, por los nuevos elementos estéticos con que se lleva a cabo, por los paralelos que se establecen entre mundo antiguo y mundo moderno o, en fin, por el modo de desplegar el genio artístico que caracteriza a cada uno de los directores escogidos. Cuatro personalidades del mundo del cine que toman el tema de la tragedia de Eurípides o de Séneca, no como mero pretexto para elaborar un mundo nuevo plagado de sus inquietudes, pero tampoco como una traslación literal del tema tal y como lo expresaron sus creadores en el mundo antiguo.This paper presents a thorough analysis of four film adaptations of the myth of Medea, which have been considered as being of great significance. This could be either for its innovative way of reinterpreting the myth due to the new aesthetic elements that are conducted, for the parallels that exist between the ancient and modern world, or due to the way of displaying the artistic genius that each of the chosen directors represent. Four personalities from the film community have taken the theme of the tragedy by Euripides and Seneca, but not as mere pretext to develop a new world plagued with apprehension, nor as a literal transfer of the topic as expressed by their creators in the ancient world.

  11. 78 FR 19362 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel W.L. STEWART III; Invitation...

    Science.gov (United States)

    2013-03-29

    ... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0026] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel W.L. STEWART III; Invitation for Public Comments AGENCY.... STEWART III is: Intended Commercial Use of Vessel: ``Yacht Club Regatta and Sailing Instruction Support...

  12. Recuperación del cromo y aluminio del licor de desecho (wl en forma de sales dobles

    Directory of Open Access Journals (Sweden)

    Pedro R. Bassas-Noa

    2006-03-01

    Full Text Available El licor WL es un residual de la industria del níquel agresivo al medio ambiente por su acidez que contiene elementos metálicos de gran valor. Se propone un tratamiento para la separación con  hidróxido de amonio y la recuperación de la mayor cantidad de cromo y aluminio contenidos en el mismo. Se logra precipitar una mezcla de hidróxidos de aluminio que tratada con ácido sulfúrico permite obtener, por cristalización, la sal sulfato de aluminio y amonio dodecahidratada. Posteriomente se cristaliza la sal sulfato doble de cromo y amonio dodecahidratado. Se demuestra que el sulfato doble de cromo y amonio dodecahidratado y el sólido separado presentan características químicas que hacen posible su aplicación en la industria textil y de cerámica, entre otras. El esquema aplicado permite la recuperación de valores metálicos y la disminución del alto poder contaminante del licor de desecho WL.

  13. Medea de Eurípides: la “atétesis” de versos y la construcción gradual de la venganza

    Directory of Open Access Journals (Sweden)

    Pablo A. Cavallero

    2003-12-01

    Full Text Available The work proposes to reexamine the athetesis and the emendations which were applied to diverse passages of Euripides' Medea, asserting that many of these are not necessary, if one understands the revenge as a decision whose method is not established from the beginning, but it is constructed gradually. This gradation provokes apparent contradictions. They are considered the following controverted passages: 40-43, 87, 261-2, 361-2, 366-7, 468, 725-6, 782, 785-6, 923-4, 1056-1080, 1121, 1220-1, 1316, 1359, 1387; and also all the play development, in order to prove the effect of those in the gradual construction of the revenge; it is taken into account the vocabulary use in the inside of the play. In this process, the passages here analysed, and discussed by the critics about his authenticity, result defensible and necessary to establish the graduation, which is verified in the inside structure, in the images and in the construction of the crime.

  14. MEDEA+ project 2T302 MUSCLE: masks through user's supply chain: leadership by excellence

    Science.gov (United States)

    Torsy, Andreas

    2008-04-01

    The rapid evolution of our information society depends on the continuous developments and innovations of semiconductor products. The cost per chip functionality keeps reducing by a factor of 2 every 18 month. However, this performance and success of the semiconductor industry critically depends on the quality of the lithographic photomasks. The need for the high quality of photomask drives lithography costs sensitively, which is a key factor in the manufacture of microelectronics devices. Therefore, the aim is to reduce production costs while overcoming challenges in terms of feature sizes, complexity and cycle times. Consequently, lithography processes must provide highest possible quality at reasonable prices. This way, the leadership in the lithographic area can be maintained and European chipmakers can stay competitive with manufacturers in the Far East and the USA. Under the umbrella of MEDEA+, a project called MUSCLE (>) has been started among leading semiconductor companies in Europe: ALTIS Semiconductor (Project Leader), ALCATEL Vacuum, ATMEL, CEA/LETI, Entegris, NXP Semiconductors, TOPPAN Photomasks, AMTC, Carl ZEISS SMS, DMS, Infineon Technologies, VISTEC Semiconductor, NIKON Precision, SCHOTT Lithotec, ASML, PHOTRONICS, IMEC, DCE, DNP Photomask, STMicroelectronics, XYALIS and iCADA. MUSCLE focuses particularly on mask data flow, photomask carrier, photomask defect characterization and photomask data handling. In this paper, we will discuss potential solutions like standardization and automation of the photomask data flow based on SEMI P10, the performance and the impact of the supply chain parameter within the photomask process, the standardization of photomask defect characterization and a discussion of the impact of new Reticle Enhancement Technologies (RET) such as mask process correction and finally a generic model to describe the photomasks key performance indicators for prototype photomasks.

  15. Efluente líquido (WL de la tecnología de lixiviación ácida: alternativas de tratamiento

    Directory of Open Access Journals (Sweden)

    Eulalia Rondón-Medina

    2003-03-01

    Full Text Available El residual conocido como WL (waste liquor se genera en la tecnología de lixiviación ácida de minerales lateríticos que aplica la empresa Pedro Sotto Alba (Compañía Moa Nickel S.A. para precipitar el níquel y el cobalto en forma de sulfuros. Este residual se descarga al río Cabañas con una concentración de metales, acidez y temperatura que superan las normas ambientales de vertimiento. En este trabajo se analizan las principales variantes de tratamiento que han resultado del estudio de esta problemática y se propone un nuevo proceso desarrollado en el Centro de Investigaciones del Níquel.

  16. Recuperación de metales del licor de desecho WL en forma de compuestos químicos

    Directory of Open Access Journals (Sweden)

    Pedro R. Bassas

    2001-03-01

    Full Text Available El licor de desecho de la empresa niquelera Pedro Soto Alba-Moa Nickel S.A., conocido como WL, es un licor de gran acidez; contiene elementos pesados junto a otros metales que no son asimilados por el proceso metalúrgico y quedan en el licor, que al verterse, impacta en forma negativa el medio ambiente. Mediante precipitación selectiva en tres etapas, se logra recuperar aluminio y manganeso en forma de sales dobles; níquel, cobalto, cobre y zinc en forma de sulfuros y un licor concentrado de cromo. Se empleó el sulfuro de sodio, el hidróxido de amonio y el hidrógenosulfuro de amonio como agentes precipitantes. El licor residual resultante de este tratamiento pierde su acidez y tiene un bajo contenido de elementos pesados que lo hacen menos agresivo al medio.

  17. Clustering with position-specific constraints on variance: Applying redescending M-estimators to label-free LC-MS data analysis

    Directory of Open Access Journals (Sweden)

    Mani D R

    2011-08-01

    Full Text Available Abstract Background Clustering is a widely applicable pattern recognition method for discovering groups of similar observations in data. While there are a large variety of clustering algorithms, very few of these can enforce constraints on the variation of attributes for data points included in a given cluster. In particular, a clustering algorithm that can limit variation within a cluster according to that cluster's position (centroid location can produce effective and optimal results in many important applications ranging from clustering of silicon pixels or calorimeter cells in high-energy physics to label-free liquid chromatography based mass spectrometry (LC-MS data analysis in proteomics and metabolomics. Results We present MEDEA (M-Estimator with DEterministic Annealing, an M-estimator based, new unsupervised algorithm that is designed to enforce position-specific constraints on variance during the clustering process. The utility of MEDEA is demonstrated by applying it to the problem of "peak matching"--identifying the common LC-MS peaks across multiple samples--in proteomic biomarker discovery. Using real-life datasets, we show that MEDEA not only outperforms current state-of-the-art model-based clustering methods, but also results in an implementation that is significantly more efficient, and hence applicable to much larger LC-MS data sets. Conclusions MEDEA is an effective and efficient solution to the problem of peak matching in label-free LC-MS data. The program implementing the MEDEA algorithm, including datasets, clustering results, and supplementary information is available from the author website at http://www.hephy.at/user/fru/medea/.

  18. Biosynthesis of gold nanoparticles by Aspergillum sp. WL-Au for degradation of aromatic pollutants

    Science.gov (United States)

    Qu, Yuanyuan; Pei, Xiaofang; Shen, Wenli; Zhang, Xuwang; Wang, Jingwei; Zhang, Zhaojing; Li, Shuzhen; You, Shengnan; Ma, Fang; Zhou, Jiti

    2017-04-01

    A simple method for synthesis of gold nanoparticles (AuNPs) using Aspergillum sp. WL-Au was presented in this study. According to UV-vis spectra and transmission electron microscopy images, the shape and size of AuNPs were affected by different parameters, including buffer solution, pH, biomass and HAuCl4 concentrations. Phosphate sodium buffer was more suitable for extracellular synthesis of AuNPs, and the optimal conditions for AuNPs synthesis were pH 7.0, biomass 100 mg/mL and HAuCl4 3 mM, leading to the production of spherical and pseudo-spherical nanoparticles. The biosynthesized AuNPs possessed excellent catalytic activities for the reduction of 2-nitrophenol, 3-nitrophenol, 4-nitrophenol, o-nitroaniline and m-nitroaniline in the presence of NaBH4, and the catalytic rate constants were calculated to be 6.3×10-3 s-1, 5.5×10-3 s-1, 10.6×10-3 s-1, 8.4×10-3 s-1 and 13.8×10-3 s-1, respectively. The AuNPs were also able to catalyze the decolorization of various azo dyes (e.g. Cationic Red X-GRL, Acid Orange II and Acid scarlet GR) using NaBH4 as the reductant, and the decolorization rates reached 91.0-96.4% within 7 min. The present study should provide a potential candidate for green synthesis of AuNPs, which could serve as efficient catalysts for aromatic pollutants degradation.

  19. "w;l

    African Journals Online (AJOL)

    well illustrated using poultry asthe experimental animal. ... namely, a quantitative expression of the way in which .... nutrients and the value of the product. ... mination of ME by publishing a new, rapid technique ... prior to, or during, each test, perhaps a constant ... stitutes a considerable saving in the cost of laying diets,.

  20. Enhancing engagement in multimodality environments by sound movement in a virtual space

    DEFF Research Database (Denmark)

    Götzen, Amalia De

    2004-01-01

    of instrumental sounds - has allowed space as a musical instrumental practice to flourish. Electro-acoustic technologies let composers explore new listening dimensions and consider the sounds coming from loudspeakers as possessing different logical meanings from the sounds produced by traditional instruments....... Medea, Adriano Guarnieri's "video opera", is an innovative work stemming from research in multimedia that demonstrates the importance and amount of research dedicated to sound movement in space. Medea is part of the Multi-sensory Expressive Gesture Application project (http://www.megaproject.org). Among...

  1. Catalytic reduction of 4-nitrophenol using gold nanoparticles biosynthesized by cell-free extracts of Aspergillus sp. WL-Au

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Wenli; Qu, Yuanyuan, E-mail: qyy@dlut.edu.cn; Pei, Xiaofang; Li, Shuzhen; You, Shengnan; Wang, Jingwei; Zhang, Zhaojing; Zhou, Jiti

    2017-01-05

    Highlights: • A green process for AuNPs synthesis was achieved by fungus Aspergillus. • Uniform spherical AuNPs with well dispersity and stability were biosynthesized. • The biogenic AuNPs possessed remarkable catalytic activities for 4-NP reduction. - Abstract: A facile one-pot eco-friendly process for synthesis of gold nanoparticles (AuNPs) with high catalytic activity was achieved using cell-free extracts of Aspergillus sp. WL-Au as reducing, capping and stabilizing agents. The surface plasmon resonance band of UV–vis spectrum at 532 nm confirmed the presence of AuNPs. Transmission electron microscopy images showed that quite uniform spherical AuNPs were synthesized and the average size of nanoparticles increased from 4 nm to 29 nm with reaction time. X-ray diffraction analysis verified the formation of nano-crystalline gold particles. Fourier transform infrared spectra showed the presence of functional groups on the surface of biosynthesized AuNPs, such as O−H, N−H, C=O, C−H, C−OH and C−O−C groups, which increased the stability of AuNPs. The biogenic AuNPs could serve as a highly efficient catalyst for 4-nitrophenol reduction. The reaction rate constant was linearly correlated with the concentration of AuNPs, which increased from 0.59 min{sup −1} to 1.51 min{sup −1} with the amount of AuNPs increasing form 1.46 × 10{sup −6} to 17.47 × 10{sup −6} mmol. Moreover, the as-synthesized AuNPs exhibited a remarkable normalized catalytic activity (4.04 × 10{sup 5} min{sup −1} mol{sup −1}), which was much higher than that observed for AuNPs synthesized by other biological and conventional chemical methods.

  2. Catalytic reduction of 4-nitrophenol using gold nanoparticles biosynthesized by cell-free extracts of Aspergillus sp. WL-Au

    International Nuclear Information System (INIS)

    Shen, Wenli; Qu, Yuanyuan; Pei, Xiaofang; Li, Shuzhen; You, Shengnan; Wang, Jingwei; Zhang, Zhaojing; Zhou, Jiti

    2017-01-01

    Highlights: • A green process for AuNPs synthesis was achieved by fungus Aspergillus. • Uniform spherical AuNPs with well dispersity and stability were biosynthesized. • The biogenic AuNPs possessed remarkable catalytic activities for 4-NP reduction. - Abstract: A facile one-pot eco-friendly process for synthesis of gold nanoparticles (AuNPs) with high catalytic activity was achieved using cell-free extracts of Aspergillus sp. WL-Au as reducing, capping and stabilizing agents. The surface plasmon resonance band of UV–vis spectrum at 532 nm confirmed the presence of AuNPs. Transmission electron microscopy images showed that quite uniform spherical AuNPs were synthesized and the average size of nanoparticles increased from 4 nm to 29 nm with reaction time. X-ray diffraction analysis verified the formation of nano-crystalline gold particles. Fourier transform infrared spectra showed the presence of functional groups on the surface of biosynthesized AuNPs, such as O−H, N−H, C=O, C−H, C−OH and C−O−C groups, which increased the stability of AuNPs. The biogenic AuNPs could serve as a highly efficient catalyst for 4-nitrophenol reduction. The reaction rate constant was linearly correlated with the concentration of AuNPs, which increased from 0.59 min −1 to 1.51 min −1 with the amount of AuNPs increasing form 1.46 × 10 −6 to 17.47 × 10 −6 mmol. Moreover, the as-synthesized AuNPs exhibited a remarkable normalized catalytic activity (4.04 × 10 5 min −1 mol −1 ), which was much higher than that observed for AuNPs synthesized by other biological and conventional chemical methods.

  3. The Role of W.L. Mackenzie King in the Development of the Canadian Political Culture (Dedicated to His 140th Anniversary

    Directory of Open Access Journals (Sweden)

    Sokov Ilya Anatolyevich

    2015-04-01

    Full Text Available The author of the article analyses the role of Canada’s Prime Minister W.L. Mackenzie King in the creation of the unique Canadian political culture. The basis for this political culture was represented not only by the British political system, the adopted ideology of English classical liberalism, but also the national historical and cultural traditions connected with one and a half century existence of two nations on the North American continent. The author confirms that the Liberal Party and Mackenzie King as its leader decided upon the wide modernization of the Canadian society in the conditions of the post-war reconstruction in 1920s. This process would have been impossible without the reorganization of the political culture. The change of political practice allowed the autonomy to obtain more rights and the sovereignty. That is why M. King held two posts during almost the whole period – as Prime Minister and as Minister of Foreign Affairs. This approach helped him to have significant influence on the external political aspect in the development of the Canadian political culture. The author of the article points the main seven directions in the political activity of Mackenzie King which contributed to the creation of the unique Canadian political culture. The author concludes that the influence of Mackenzie King on the creation of the Canadian political culture was crucial in the second half of the 20th Century.

  4. Phase Manifestation and Formation of Nanoemulsions Composed of Imidazolium-based Ionic Liquid, Tween 80/Span 80 and Labrafac Lipophile WL 1349

    Directory of Open Access Journals (Sweden)

    S. H. Ng

    2017-07-01

    Full Text Available onic liquids (ILs can enhance topical and transdermal delivery, as well as increase the solubility of sparingly soluble drugs. In the present work, pseudo-ternary phase diagrams of emulsions were composed of a mixture of non-ionic surfactants, polyoxyethylene sorbitan monooleate (Tween 80® and sorbitan monooleate (Span 80® in weight fraction: 1:1, 1:2, 2:1 and 2:3, LabrafacTM Lipophile WL 1349 as an oil phase and 1-hexyl-3-methylimidazolium chloride [(HMIM (Cl] as a continuous phase. Emulsion formulations were selected with 10% surfactants from the pseudo-ternary phase diagrams and further prepared at 298.2 ± 0.1 K. Acoustic emulsificationmethod was used to prepare nanoemulsions that were mixed with freshly prepared hydrocolloid gum. The area of the single-phase zone in pseudo-ternary phase diagrams that varied with Tween 80® /Span 80® ratio in the order of 2:1 > 1:1 > 2:3 > 1:2 where Span 80® was replaced by an equivalent weight of Tween 80®  to form IL-based nanoemulsions. [HMIM] [Cl] tended to create a two-phase system. Addition of carbopol® ultrez 20 copolymer into the continuous phase of the formulations gave single-phase nanoemulsions with good stability. The mixture of surfactants with weight ratio of 1:2 (Tween 80®/Span 80® showed a good stability with the smallest particle size and greater surface charges in the system. These ionic liquid-based nanoemulsions might have the potential in drug delivery systems.

  5. Suvi õues / Ivi-Els Schneider

    Index Scriptorium Estoniae

    Schneider, Ivi-Els, 1945-

    2004-01-01

    Õuemööblit Eesti kodudest. 9 ill.: Verner Pantoni kavandatud plastiktool, Albero Medea kavandatud lamamistool, dirigent Tõnu Kaljuste pink mererannas, viljapeksumasina hammasrattast laud, puust kiikhobune jm.

  6. EUMEDEA: una iniziativa europea per la formazione di docenti dell'educazione Ambientale

    Directory of Open Access Journals (Sweden)

    Vittorio Midoro

    1998-01-01

    Full Text Available Course description EuMEDEA concerning the training of teachers in service that has as its object a methodological proposal to develop and conduct environmental education projects at European level.

  7. 76 FR 819 - Requested Administrative Waiver of the Coastwise Trade Laws

    Science.gov (United States)

    2011-01-06

    ... Museum. The Medea is an elegant 1904 Edwardian steam yacht and is the only steam-powered yacht on the west coast. It was built as a private yacht, but was commandeered into Allied service in both World War...

  8. Medea’s Four Reasons

    Directory of Open Access Journals (Sweden)

    Marco Gemin

    2014-11-01

    Full Text Available The same motivations (eros, logos, bia, theos are attributed by Gorgias to Helen and by Euripides to Medea, which suggests the writers’ common intellectual ground, though the motivations are alternative in Gorgias, simultaneous in Euripides.

  9. Relationship of 220Rn and 222Rn progeny levels in Canadian underground U mines

    International Nuclear Information System (INIS)

    Bigu, J.

    1988-01-01

    Radon-222 and 220 Rn progeny are found in some Canadian underground U mines. Because both can contribute to lung dose, their experimental determinations are important. The relationship between 222 Rn progeny Working Level [WL(Rn)] and 220 Rn progeny Working Level [WL(Tn)] has been investigated in U mines. Experimental measurements extended from 1981 to 1986 and consisted of about 700 measurements of each WL(Rn) and WL(Tn). The data were analyzed by standard linear and power-function regression analysis. A power-function relationship between WL(Rn) and WL(Tn) seemed to fit the experimental data best. The relationship obtained permits the calculation of WL(Tn) from experimental values of WL(Rn). The relationship is useful for lung-dose-calculation purposes and in mine-ventilation-engineering calculations

  10. TPÜ Akadeemilise Raamatukogu ajaloolised kogud rahvusvahelistes infoallikates / Tiiu Reimo

    Index Scriptorium Estoniae

    Reimo, Tiiu, 1953-

    2005-01-01

    Lk. 99 mainitud : Urve Lõhmus, Voldemar Miller, Tiiu Reimo; lk. 100 : Voldemar Miller, Kyra Robert; lk. 102 : Tiiu Reimo, Medea Jerser, Toomas Raudam; lk. 103 : Antti Oviir, Aita Jõulu; lk. 104 : Tiiu Reimo, Marita Paas, Mati Merioja, Tiiu Pukk, Eve Roosileht

  11. Mercury and water level fluctuations in lakes of northern Minnesota

    Science.gov (United States)

    Larson, James H.; Maki, Ryan P; Christensen, Victoria G.; Sandheinrich, Mark B.; LeDuc, Jaime F.; Kissane, Claire; Knights, Brent C.

    2017-01-01

    Large lake ecosystems support a variety of ecosystem services in surrounding communities, including recreational and commercial fishing. However, many northern temperate fisheries are contaminated by mercury. Annual variation in mercury accumulation in fish has previously been linked to water level (WL) fluctuations, opening the possibility of regulating water levels in a manner that minimizes or reduces mercury contamination in fisheries. Here, we compiled a long-term dataset (1997-2015) of mercury content in young-of-year Yellow Perch (Perca flavescens) from six lakes on the border between the U.S. and Canada and examined whether mercury content appeared to be related to several metrics of WL fluctuation (e.g., spring WL rise, annual maximum WL, and year-to-year change in maximum WL). Using simple correlation analysis, several WL metrics appear to be strongly correlated to Yellow Perch mercury content, although the strength of these correlations varies by lake. We also used many WL metrics, water quality measurements, temperature and annual deposition data to build predictive models using partial least squared regression (PLSR) analysis for each lake. These PLSR models showed some variation among lakes, but also supported strong associations between WL fluctuations and annual variation in Yellow Perch mercury content. The study lakes underwent a modest change in WL management in 2000, when winter WL minimums were increased by about 1 m in five of the six study lakes. Using the PLSR models, we estimated how this change in WL management would have affected Yellow Perch mercury content. For four of the study lakes, the change in WL management that occurred in 2000 likely reduced Yellow Perch mercury content, relative to the previous WL management regime.

  12. Chadwick: Symphony No. 3 in F; Barber: Vanessa-Intermezzo / Andrew Achenbach

    Index Scriptorium Estoniae

    Achenbach, Andrew

    1994-01-01

    Uuest heliplaadist "Chadwick: Symphony No. 3 in F; Barber: Vanessa-Intermezzo, Under the Willow Tree. Music for a scene from Shelley, Op. 7. Medea's Meditation and Dance of Vengeance, Op. 23a. Detroit Symphony Orchestra / Neeme Järvi." Chandos CD CHAN 9253

  13. Invertebrate post-segregation distorters: a new embryo-killing gene.

    Directory of Open Access Journals (Sweden)

    Steven P Sinkins

    2011-07-01

    Full Text Available Cytoplasmic incompatibility induced by inherited intracellular bacteria of arthropods, and Medea elements found in flour beetles, are both forms of postsegregation distortion involving the killing of embryos in order to increase the ratio of progeny that inherit them. The recently described peel-zeel element of Caenorhabditis elegans also uses this mechanism; like Medea the genes responsible are in the nuclear genome but it shares a paternal mode of action with the bacteria. The peel-1 gene has now been shown to encode a potent toxin that is delivered by sperm, and rescued by zygotic transcription of the linked zeel-1. The predominance of self-fertilization in C. elegans has produced an unusual distribution pattern for a selfish genetic element; further population and functional studies will shed light on its evolution. The element might also have potential for use in disease control.

  14. Contrasting response to nutrient manipulation in Arctic mesocosms are reproduced by a minimum microbial food web model.

    Science.gov (United States)

    Larsen, Aud; Egge, Jorun K; Nejstgaard, Jens C; Di Capua, Iole; Thyrhaug, Runar; Bratbak, Gunnar; Thingstad, T Frede

    2015-03-01

    A minimum mathematical model of the marine pelagic microbial food web has previously shown to be able to reproduce central aspects of observed system response to different bottom-up manipulations in a mesocosm experiment Microbial Ecosystem Dynamics (MEDEA) in Danish waters. In this study, we apply this model to two mesocosm experiments (Polar Aquatic Microbial Ecology (PAME)-I and PAME-II) conducted at the Arctic location Kongsfjorden, Svalbard. The different responses of the microbial community to similar nutrient manipulation in the three mesocosm experiments may be described as diatom-dominated (MEDEA), bacteria-dominated (PAME-I), and flagellated-dominated (PAME-II). When allowing ciliates to be able to feed on small diatoms, the model describing the diatom-dominated MEDEA experiment give a bacteria-dominated response as observed in PAME I in which the diatom community comprised almost exclusively small-sized cells. Introducing a high initial mesozooplankton stock as observed in PAME-II, the model gives a flagellate-dominated response in accordance with the observed response also of this experiment. The ability of the model originally developed for temperate waters to reproduce population dynamics in a 10°C colder Arctic fjord, does not support the existence of important shifts in population balances over this temperature range. Rather, it suggests a quite resilient microbial food web when adapted to in situ temperature. The sensitivity of the model response to its mesozooplankton component suggests, however, that the seasonal vertical migration of Arctic copepods may be a strong forcing factor on Arctic microbial food webs.

  15. Critical weight loss is a major prognostic indicator for disease-specific survival in patients with head and neck cancer receiving radiotherapy

    OpenAIRE

    Langius, J.A.E.; Bakker, S.; Rietveld, D.H.F.; Kruizenga, H.M.; Langendijk, J.A.; Weijs, P.J.M.; Leemans, C.R.

    2013-01-01

    Background:Pre-treatment weight loss (WL) is a prognostic indicator for overall survival (OS) in head and neck cancer (HNC) patients. This study investigates the association between WL before or during radiotherapy and disease-specific survival (DSS) in HNC patients.Methods:In 1340 newly diagnosed HNC patients, weight change was collected before and during (adjuvant) radiotherapy with curative intent. Critical WL during radiotherapy was defined as >5% WL during radiotherapy or >7.5% WL until ...

  16. Effect of wetting-layer density of states on the gain and phase recovery dynamics of quantum-dot semiconductor optical amplifiers

    International Nuclear Information System (INIS)

    Kim, Jungho; Yu, Bong-Ahn

    2015-01-01

    We numerically investigate the effect of the wetting-layer (WL) density of states on the gain and phase recovery dynamics of quantum-dot semiconductor optical amplifiers in both electrical and optical pumping schemes by solving 1088 coupled rate equations. The temporal variations of the ultrafast gain and phase recovery responses at the ground state (GS) are calculated as a function of the WL density of states. The ultrafast gain recovery responses do not significantly depend on the WL density of states in the electrical pumping scheme and the three optical pumping schemes such as the optical pumping to the WL, the optical pumping to the excited state ensemble, and the optical pumping to the GS ensemble. The ultrafast phase recovery responses are also not significantly affected by the WL density of states except the optical pumping to the WL, where the phase recovery component caused by the WL becomes slowed down as the WL density of states increases. (paper)

  17. Timeline of changes in adaptive physiological responses, at the level of energy expenditure, with progressive weight loss.

    Science.gov (United States)

    Nymo, Siren; Coutinho, Silvia R; Torgersen, Linn-Christin H; Bomo, Ola J; Haugvaldstad, Ingrid; Truby, Helen; Kulseng, Bård; Martins, Catia

    2018-05-07

    Diet-induced weight loss (WL) is associated with reduced resting and non-resting energy expenditure (EE), driven not only by changes in body composition but also potentially by adaptive thermogenesis (AT). When exactly this happens, during progressive WL, remains unknown. The aim of this study was to determine the timeline of changes in RMR and exercise-induced EE (EIEE), stemming from changes in body composition v. the presence of AT, during WL with a very-low-energy diet (VLED). In all, thirty-one adults (eighteen men) with obesity (BMI: 37 (sem 4·5) kg/m2; age: 43 (sem 10) years) underwent 8 weeks of a VLED, followed by 4 weeks of weight maintenance. Body weight and composition, RMR, net EIEE (10, 25 and 50 W) and AT (for RMR (ATRMR) and EIEE (ATEIEE)) were measured at baseline, day 3 (2 (sem 1) % WL), after 5 and 10 % WL and at weeks 9 (16 (sem 2) %) and 13 (16 (sem 1) %). RMR and fat mass were significantly reduced for the first time at 5 % WL (12 (sem 8) d) (P<0·01 and P<0·001, respectively) and EIEE at 10 % WL (32 (sem 8) d), for all levels of power (P<0·05), and sustained up to week 13. ATRMR was transiently present at 10 % WL (-460 (sem 690) kJ/d, P<0·01). A fall in RMR should be anticipated at ≥5 % WL and a reduction in EIEE at ≥10 % WL. Transient ATRMR can be expected at 10 % WL. These physiological adaptations may make progressive WL difficult and will probably contribute to relapse.

  18. Relations between mental workload and decision-making in an organizational setting

    Directory of Open Access Journals (Sweden)

    María Soria-Oliver

    2017-05-01

    Full Text Available Asbtract Background The complexity of current organizations implies a potential overload for workers. For this reason, it is of interest to study the effects that mental workload has on the performance of complex tasks in professional settings. Objective The objective of this study is to empirically analyze the relation between the quality of decision-making, on the one hand, and the expected and real mental workload, on the other. Methods The study uses an ex post facto prospective design with a sample of 176 professionals from a higher education organization. Expected mental workload (Pre-Task WL and real mental workload (Post-Task WL were measured with the unweighted NASA-Task Load Index (NASA-TLX questionnaire; difference between real WL and expected WL (Differential WL was also calculated; quality of decision-making was measured by means of the Decision-Making Questionnaire. Results General quality of decision-making and Pre-Task WL relation is compatible with an inverted U pattern, with slight variations depending on the specific dimension of decision-making that is considered. There were no verifiable relations between Post-Task WL and decision-making. The subjects whose expected WL matched the real WL showed worse quality in decision-making than subjects with high or low Differential WL. Conclusions The relations between mental workload and decision-making reveal a complex pattern, with evidence of nonlinear relations.

  19. OS FRAGMENTOS DE NARRATIVA MÍTICA DA PRINCESA DE COLCHIS -CÓLQUIDA. (Dossiê: O Mundo Antigo: Literatura e Historiografia

    Directory of Open Access Journals (Sweden)

    Maria Regina Cândido

    2015-09-01

    Full Text Available Resumo: Este artigo trata das representações do mito de Medeia na poética e na cultura material, compreendendo a dinâmica interativa entre a escrita e a figuração por meio do verbo graphein na cultura grega. Trata também das representações deste mito na arte cinematográfica, pondo em evidência a transcendência de sua narrativa mítica ao expressar problemas inerentes à humanidade.Palavras-chaves: Medeia, Representação, CinematografiaAbstract: This article deals with the representations of the Myth of Medea in the poetic and material culture, including the interactive dynamic between writing and figuration through the verb graphein in Greek culture. It also deals with the representations of this myth in the cinematography, highlighting the transcendence of this mythical narrative to express humanity problems.Key words: Medea, Representation, Cinematography.Recebido em: 22/07/2015  – Aceito em 07/09/2015

  20. Effects of Hen Age and Egg Weight Class on the Hatchability of Free Range Indigenous Chicken Eggs

    Directory of Open Access Journals (Sweden)

    AM Abudabos

    Full Text Available ABSTRACT In total, 806 eggs of free-range Hassawi indigenous chickens were collected from local farm in Saudi Arabia. Eggs were weekly collected for 11 weeks. Initial egg weight (IEW was recorded, and eggs were graded into four classes (A: 35-40 g, B: 40-45 g, C: 45-50 g, and D: 50-55 g. Eggs were stored for seven days at 75-80% relative humidity and 14-16 C, after which egg weight losses (WL0 were calculated. During incubation, eggs were weighed on days 7 (W7 and 14 (W14, and egg weight losses on days 7 (WL7 and 14 (WL14, and total loss (WL0-14 were calculated. Hatchling weight (CW was measured. The proportion of CW relative to egg weight loss (WL on days0, 7 and 14 days of incubation (CW:WL0; CW:WL7 and CW:WL14, respectively, and break out analyses, fertility (F,total hatchability (HC and hatchability of fertile eggs (HF were also calculated. IEW decreased (p<0.05 with hen age. Stored egg weight (SEW were decreased as hen age increased (p<0.05. WL7, WL14 and WL0-14 showed significant differences (p<0.001 and increased up to first six-week of egg collection time. Hen age affected CW:WL before incubation, and on days 7 and 14 of incubation. Fertility (F was affected (p<0.05 in unpredicted way of increasing and decreasing by hen age. Egg weight class affected SEW, W7and W14 (p<0.001. Class D eggs were the highest weight. Class C eggs had highest HC. In summary, hatching eggs of Hassawi hens were affected by hen age and egg weight in randomly increase and decrease .

  1. House characteristics associated with gamma radiation and radon daughter working levels in eastern Pennsylvania

    International Nuclear Information System (INIS)

    Stebbings, J.H.; Dignam, J.J.; Reilly, M.A.; Gerusky, T.M.; Hartman, T.T.; Anast, G.A.

    1987-01-01

    Working levels (WL) of radon daughters and γ measurements in basements are described for ∼1200 houses near the Reading Prong. House variables studied included condition and construction materials of basement floors and walls, basement heights and areas, heating systems, air conditioning, water supply, and presence of drains and sump pumps. WL's were poorly predicted by house characteristics or γ measurements, while γ levels were well predicted by house characteristics and WL. Except for windowless basements, associated with both high γ andl high WL measurements, factors predicting high γ levels tended to be associated with low WL's and vice versa. Dirt basement floors and fieldstone basement walls were strongly associated with high γ levels, as were poor wall conditions in multivariate analyses. Gamma levels were low in electrically heated homes. High WL's were strongly associated with electric heat, low WL's with basement walls of fieldstone and/or in poor condition. Large house volumes and well water supply were also associated with higher WL's. 4 refs., 1 fig., 4 tabs

  2. Incidence of Apical Crack Initiation during Canal Preparation using Hand Stainless Steel (K-File) and Hand NiTi (Protaper) Files.

    Science.gov (United States)

    Soni, Dileep; Raisingani, Deepak; Mathur, Rachit; Madan, Nidha; Visnoi, Suchita

    2016-01-01

    To evaluate the incidence of apical crack initiation during canal preparation with stainless steel K-files and hand protaper files (in vitro study). Sixty extracted mandibular premo-lar teeth are randomly selected and embedded in an acrylic tube filled with autopolymerizing resin. A baseline image of the apical surface of each specimen was recorded under a digital microscope (80×). The cervical and middle thirds of all samples were flared with #2 and #1 Gates-Glidden (GG) drills, and a second image was recorded. The teeth were randomly divided into four groups of 15 teeth each according to the file type (hand K-file and hand-protaper) and working length (WL) (instrumented at WL and 1 mm less than WL). Final image after dye penetration and photomicrograph of the apical root surface were digitally recorded. Maximum numbers of cracks were observed with hand protaper files compared with hand K-file at the WL and 1 mm short of WL. Chi-square testing revealed a highly significant effect of WL on crack formation at WL and 1 mm short of WL (p = 0.000). Minimum numbers of cracks at WL and 1 mm short of WL were observed with hand K-file and maximum with hand protaper files. Soni D, Raisingani D, Mathur R, Madan N, Visnoi S. Incidence of Apical Crack Initiation during Canal Preparation using Hand Stainless Steel (K-File) and Hand NiTi (Protaper) Files. Int J Clin Pediatr Dent 2016;9(4):303-307.

  3. Uncertainties in estimating working level months

    International Nuclear Information System (INIS)

    Johnson, J.R.

    1978-11-01

    A statistical procedure is presented that can be used to estimate the number of Working Level (WL) measurements that are required to calculate the average WL to any required precision, at given confidence levels. The procedure assumes that the WL measurements have a normal distribution. WL measurement from Canadian Uranium mines are used to illustrate a procedure of insuring that estimated Working Level Months can be calculated to the required precision. An addendum reports the results of tests of normality of the WL data using the W-test and the Kolmagornov-Smirnov test. (author)

  4. Estudio cinético del proceso de precipataión de los sulfuros de níquel y cobalto con hidrógeno sulfuro de sodio, en el licor de desecho (WL

    Directory of Open Access Journals (Sweden)

    Mercedes Sosa-Martínez

    2006-03-01

    Full Text Available En el trabajo se realiza un estudio cinético del proceso de precipitación de sulfuros a partir del licor residual WL que se genera en la Empresa Moa Níckel S. A -Pedro Soto Alba. La investigación se realiza a escala de laboratorio empleando una variante de tratamiento del licor en dos etapas de precipitación a diferentes valores de pH, donde se analiza la influencia de los factores que intervienen en el proceso como la temperatura, concentración de hidrógeno sulfuro de sodio y el régimen de agitación, basado en el método factorial completo donde se conjugan los niveles experimentales de las variables estudiadas respecto al grado de precipitación de los principales elementos níquel cobalto, cinc, y cobre. En la primera etapa se logra obtener una mezcla de sulfuros mixtos ricos en  cobre y cinc con extracciones superiores  a  80 % y 64 % respectivamente, mientras que en la segunda etapa se obtiene un precipitado de color negro correspondiente a los sulfuros de níquel y cobalto cuyas recuperaciones alcanzan valores de 84% y  82%.

  5. Litter type affects the activity of aerobic decomposers in a boreal peatland more than site nutrient and water level regimes

    Science.gov (United States)

    Straková, P.; Niemi, R. M.; Freeman, C.; Peltoniemi, K.; Toberman, H.; Heiskanen, I.; Fritze, H.; Laiho, R.

    2011-02-01

    Peatlands are carbon (C) storage ecosystems sustained by a high water level (WL). High WL creates anoxic conditions that suppress the activity of aerobic decomposers and provide conditions for peat accumulation. Peatland function can be dramatically affected by WL drawdown caused by land-use and/or climate change. Aerobic decomposers are directly affected by WL drawdown through environmental factors such as increased oxygenation and nutrient availability. Additionally, they are indirectly affected via changes in plant community composition and litter quality. We studied the relative importance of direct and indirect effects of WL drawdown on aerobic decomposer activity in plant litter. We did this by profiling 11 extracellular enzymes involved in the mineralization of organic C, nitrogen, phosphorus and sulphur. Our study sites represented a three-stage chronosequence from pristine (undrained) to short-term (years) and long-term (decades) WL drawdown conditions under two nutrient regimes. The litter types included reflected the prevalent vegetation, i.e., Sphagnum mosses, graminoids, shrubs and trees. WL drawdown had a direct and positive effect on microbial activity. Enzyme allocation shifted towards C acquisition, which caused an increase in the rate of decomposition. However, litter type overruled the direct effects of WL drawdown and was the main factor shaping microbial activity patterns. Our results imply that changes in plant community composition in response to persistent WL drawdown will strongly affect the C dynamics of peatlands.

  6. Senekos dramų herojų jausmų raiška ir poveikis žiūrovams. Expression of the feelings of the characters and impact on the spectators in Seneca’s dramas

    Directory of Open Access Journals (Sweden)

    Jovita Dikmonienė

    2008-01-01

    Full Text Available On the basis of the works by Taplin, Nussbaum, and Schiesar, the article explores the feelings of the protagonists of Seneca’s tragedies, Thyestes and Medea, which are the factors that develop the plot and the dynamics of the tragedies. The article also reviews the emotions these tragedies may set up in the spectators and readers. A comparison is draw between these tragedies and three philosophical dialogues of Seneca On Anger. The article investigates why and how the hatred and fury of the protagonists grows and develops. Anger is shown as pain by Seneca. Such words as ira and dolor are used as synonyms in the tragedies. The protagonists’ emotions of anger and rage cause the spectators’ fear.In Thyestes and Medea, very much like in his philosophical piece On Anger, Seneca discloses the feeling of anger of the main characters in three stages. In the first stage, the poet depicts involuntary anger of Medea with Jason who has broken the vows of love. In Thyestes, Atreus is angry with Thyestes who has insulted his glory. In stages one and three the characters talk to their spirit and the feeling of anger as if with an ostensible, imaginable interlocutor. In stage two, Seneca discloses extensive pride of the protagonists, the feeling of anger that is managed and controlled, their accusations to the offenders, and their wilful determination to revenge. In stage three, the poet depicts wild and uncontrollable anger and fury when Medea and Atreus kill children not because of any need, but because the passion of anger blinds the wisdom. The first and third stages of anger are shown by Seneca as uncontrollable and unconscious, whereas the second stage of anger – a conscious when the protagonists can control their passions, yet they succumb to them.In the tragedies, like in the essay On Anger, Seneca focuses on the depiction of the consequences of anger and the damage that the failure to control anger in due time brings to a man and the people

  7. Cultura e identidade na pólis grega: modelos femininos em Medéia e Lisístrata

    Directory of Open Access Journals (Sweden)

    Márcio Santos de Santana

    2008-01-01

    Full Text Available This paper examines the female models present in works Medea and Lysistrata, written respectively by Euripides and Aristofanes. The objective is to demonstrate the conservatism of conceptions about women present in them. Because of the particularity of sources perform quick discussion on the relationship between Literature and History.

  8. Medical weight loss versus bariatric surgery: does method affect body composition and weight maintenance after 15% reduction in body weight?

    Science.gov (United States)

    Kulovitz, Michelle G; Kolkmeyer, Deborah; Conn, Carole A; Cohen, Deborah A; Ferraro, Robert T

    2014-01-01

    The aim of this study was to investigate body composition changes in fat mass (FM) to lean body mass (LBM) ratios following 15% body weight loss (WL) in both integrated medical treatment and bariatric surgery groups. Obese patients (body mass index [BMI] 46.6 ± 6.5 kg/m(2)) who underwent laparoscopic gastric bypass surgery (BS), were matched with 24 patients undergoing integrated medical and behavioral treatment (MT). The BS and MT groups were evaluated for body weight, BMI, body composition, and waist circumference (WC) at baseline and after 15% WL. Following 15% body WL, there were significant decreases in %FM and increased %LBM (P maintenance of WL at 1 y were found. For both groups, baseline FM was found to be negatively correlated with percentage of weight regained (%WR) at 1 y post-WL (r = -0.457; P = 0.007). Baseline WC and rate of WL to 15% were significant predictors of %WR only in the BS group (r = 0.713; P = 0.020). If followed closely by professionals during the first 15% body WL, patients losing 15% weight by either medical or surgical treatments can attain similar FM:LBM loss ratios and can maintain WL for 1 y. Copyright © 2014 Elsevier Inc. All rights reserved.

  9. High-Protein Intake during Weight Loss Therapy Eliminates the Weight-Loss-Induced Improvement in Insulin Action in Obese Postmenopausal Women

    Directory of Open Access Journals (Sweden)

    Gordon I. Smith

    2016-10-01

    Full Text Available High-protein (HP intake during weight loss (WL therapy is often recommended because it reduces the loss of lean tissue mass. However, HP intake could have adverse effects on metabolic function, because protein ingestion reduces postprandial insulin sensitivity. In this study, we compared the effects of ∼10% WL with a hypocaloric diet containing 0.8 g protein/kg/day and a hypocaloric diet containing 1.2 g protein/kg/day on muscle insulin action in postmenopausal women with obesity. We found that HP intake reduced the WL-induced decline in lean tissue mass by ∼45%. However, HP intake also prevented the WL-induced improvements in muscle insulin signaling and insulin-stimulated glucose uptake, as well as the WL-induced adaptations in oxidative stress and cell structural biology pathways. Our data demonstrate that the protein content of a WL diet can have profound effects on metabolic function and underscore the importance of considering dietary macronutrient composition during WL therapy for people with obesity.

  10. Extracellular matrix remodeling and matrix metalloproteinase inhibition in visceral adipose during weight cycling in mice.

    Science.gov (United States)

    Caria, Cíntia Rabelo E Paiva; Gotardo, Érica Martins Ferreira; Santos, Paola Souza; Acedo, Simone Coghetto; de Morais, Thainá Rodrigues; Ribeiro, Marcelo Lima; Gambero, Alessandra

    2017-10-15

    Extracellular matrix (ECM) remodeling is necessary for a health adipose tissue (AT) expansion and also has a role during weight loss. We investigate the ECM alteration during weight cycling (WC) in mice and the role of matrix metalloproteinases (MMPs) was assessed using GM6001, an MMP inhibitor, during weight loss (WL). Obesity was induced in mice by a high-fat diet. Obese mice were subject to caloric restriction for WL followed by reintroduction to high-fat diet for weight regain (WR), resulting in a WC protocol. In addition, mice were treated with GM6001 during WL period and the effects were observed after WR. Activity and expression of MMPs was intense during WL. MMP inhibition during WL results in inflammation and collagen content reduction. MMP inhibition during WL period interferes with the period of subsequent expansion of AT resulting in improvements in local inflammation and systemic metabolic alterations induced by obesity. Our results suggest that MMPs inhibition could be an interesting target to improve adipose tissue inflammation during WL and to support weight cyclers. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Sociale, økonomiske og kulturelle aspekter ved whiplash

    DEFF Research Database (Denmark)

    Rasmussen, Claus; Stenager, Elsebeth; Nielsen, Claus Vinther

    2010-01-01

    The sequelae following whiplash injuries (WL) entail considerable human costs and expenses for both treatment and social services, especially public income benefits. Frequently, many players are involved after WL and good intersectional collaboration is therefore essential to counter the WL...

  12. Reading aloud and solving simple arithmetic calculation intervention (Learning therapy improves inhibition, verbal episodic memory, focus attention, and processing speed in healthy elderly people: Evidence from a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Rui eNouchi

    2016-05-01

    Full Text Available BackgroundPrevious reports have described that simple cognitive training using reading aloud and solving simple arithmetic calculations, so-called learning therapy, can improve executive functions and processing speed in the older adults. Nevertheless, it is not well-known whether learning therapy improve a wide range of cognitive functions or not. We investigated the beneficial effects of learning therapy on various cognitive functions in healthy older adults.MethodsWe used a single-blinded intervention with two groups (learning therapy group: LT and waiting list control group: WL. Sixty-four elderly were randomly assigned to LT or WL. In LT, participants performed reading Japanese aloud and solving simple calculations training tasks for 6 months. WL did not participate in the intervention. We measured several cognitive functions before and after 6 months intervention periods.ResultsCompared to WL, results revealed that LT improved inhibition performance in executive functions (Stroop: LT (Mean = 3.88 vs. WL (Mean = 1.22, adjusted p =.013 and reverse Stroop LT (Mean = 3.22 vs. WL (Mean = 1.59, adjusted p =.015, verbal episodic memory (logical memory: LT (Mean = 4.59 vs. WL (Mean = 2.47, adjusted p =.015, focus attention(D-CAT: LT (Mean = 2.09 vs. WL (Mean = -0.59, adjusted p =.010 and processing speed compared to the waiting list control group (digit symbol coding: LT (Mean = 5.00 vs. WL (Mean = 1.13, adjusted p =.015 and symbol search: LT (Mean = 3.47 vs. WL (Mean = 1.81, adjusted p =.014.DiscussionThis RCT can showed the benefit of learning therapy on inhibition of executive functions, verbal episodic memory, focus attention, and processing speed in healthy elderly people. Our results were discussed under overlapping hypothesis.Trial registrationThis trial was registered in The University Hospital Medical Information Network Clinical Trials Registry (UMIN000006998.

  13. Community Weight Loss to Combat Obesity and Disability in At-Risk Older Adults.

    Science.gov (United States)

    Rejeski, W Jack; Ambrosius, Walter T; Burdette, Jonathan H; Walkup, Michael P; Marsh, Anthony P

    2017-10-12

    Among older, overweight, and obese adults with either cardiovascular disease or the metabolic syndrome, reduced mobility and loss of leg strength are important risk factors for morbidity, disability, and mortality. It is unclear whether community-based approaches to weight loss may be an effective solution to this public health challenge. An 18-month three-site, randomized controlled trial conducted by YMCA staff, with blinded assessors, enrolled 249 older, overweight, and obese adults with either cardiovascular disease or metabolic syndrome with randomization to three interventions: weight loss alone (WL), weight loss + aerobic training (WL + AT), and weight loss + resistance training (WT + RT). The dual primary outcomes were 400-m walk time in seconds and knee extensor strength in Newton meters. All groups lost weight from baseline: average baseline adjusted change of -6.1% (95% confidence interval [CI]: -7.5 to -4.7) for WL only, -8.6% (95% CI: -10.0 to -7.2) for WL + AT, and -9.7% (95% CI: -11.1 to -8.4) for WL + RT. Combined, the two physical activity + WL training groups had greater improvement in walk time than WL alone (mean difference 16.9 seconds [95% CI: 9.7 to 24.0], p < .0001). Baseline adjusted change in knee extensor strength was no greater with WL + RT than WL + AT (mean difference -3.6 Nm [95% CI: -7.5 to 0.3], p = .07). At risk, older, overweight and obese adults can achieve clinically significant reductions in body weight with community-based weight loss programs. The change in percent weight loss and improvements in mobility are significantly enhanced when either RT or AT is combined with dietary WL. © The Author 2017. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  14. Metabolic Benefits of Prior Weight Loss with and without Exercise on Subsequent 6-Month Weight Regain.

    Science.gov (United States)

    Ryan, Alice S; Serra, Monica C; Goldberg, Andrew P

    2018-01-01

    To determine the 6-month follow-up effects after intentional 6-month weight loss alone (WL) and after weight loss with aerobic exercise (AEX + WL) on body composition, glucose metabolism, and cardiovascular disease risk factors in older postmenopausal women and to identify the mechanisms for weight regain. Women (n = 65, BMI > 25 kg/m 2 ) underwent maximal oxygen consumption testing, dual-energy x-ray absorptiometry, computed tomography scans, and oral glucose tolerance tests before and after 6 months of AEX + WL or WL and at 12 months ad libitum follow-up. Insulin sensitivity (M) (hyperinsulinemic-euglycemic clamp) was measured at baseline and 6 months. Thirty WL and thirty-five AEX + WL women completed a follow-up at 12 months. Similar weight loss was observed (-8%) in both groups from 0 to 6 months. Total fat mass, fat-free mass, visceral fat area, subcutaneous abdominal and midthigh fat areas, fasting glucose, insulin levels, homeostatic model assessment of insulin resistance (HOMA-IR), insulin areas under the curve, and triglyceride levels decreased similarly after WL and AEX + WL and remained lower at 12 months than at baseline, despite weight regain at 12 months. Initial M was associated with weight regain (r = -0.40, P < 0.01). Weight regain was related to independent changes in leptin and HOMA-IR from 6 to 12 months in a multiple regression model (r = 0.77, P < 0.0001). Reductions in body fat and improvements in insulin sensitivity after AEX + WL and WL were maintained at 12 months despite modest weight regain. Baseline insulin resistance partially predicted the magnitude of weight regain in postmenopausal women. © 2017 The Obesity Society.

  15. Working length changes in curved canals after coronal flaring by using rotary files and hand file: An in vitro study.

    Science.gov (United States)

    Kumar, Rahul; Khambete, Neha; Patil, Suvarna; Hoshing, Upendra; Medha, Ashish; Shetty, Roshan

    2013-09-01

    This in vitro investigation examined the effect of early coronal flaring (CF) and late CF on the working length (WL) in curved root canals. The objective of this study was to determine if canal length is altered as a result of CF in curved canals of molar roots. The conditions compared were combinations of (a) stainless steel hand files using Gates Glidden (G. G.) drills (SS) versus nickel-titanium rotary files (Ni-Ti); and (b) early CF (flaring completed before WL determination) versus late CF (flaring completed after WL determination). Selected were 90 canals of extracted maxillary or mandibular first molars (mesial root of mandibular molars and the mesiobuccal root of the maxillary molars) from three groups. CF was accomplished for the SS group using G. G. drills and for the Ni-Ti group using rotary ProTaper and Hero Shaper files. WL was determined by a digital vernier caliper before CF, immediately after CF, and again after canal preparation. A repeated measures analysis of variance (ANOVA) test and a Tukey's multiple prosthoc test were used for this study. Results indicated that WL decreased for all canals as a result of canal preparation. The mean decrease in WL was significantly greater for the SS group (-0.77 ± 0.42 mm) than for the Ni-Ti groups (-0.33 mm ± 0.44). Less change in WL occurred in all groups when initial WL was determined after CF. WL in curved canals consistently decreases during the course of instrumentation. Clinician should keep this in mind for better treatment outcome.

  16. A pilot study on the functional performance and acceptability of an innovative female condom (Wondaleaf®) in Malaysia.

    Science.gov (United States)

    Ting, Rachel Sing-Kiat; Wong, Ee-Lynn; Tnay, Jessie Koh-Sing

    2018-01-01

    Female condom (FC) has been available for over 30 years, but it still lacks wide acceptability. To overcome misdirection and invagination occurring in FC and to provide a wider area of protection, Wondaleaf ® (WL), a new-generation adhesive FC, was recently invented. This pioneering study sought to assess the acceptability and functional performance of WL among Malaysian women. A mixed method survey was conducted in three cities of Malaysia, recruiting sexually active heterosexual women, aged 18-50, by snowball sampling method. Participants were provided with WL and initially surveyed to rate its performance in five coital usages over 2 months. After that, the participants underwent a second survey to rate their satisfaction and acceptability toward WL. Descriptive statistics on clinical failure rates were tabulated with correlational analysis performed to identify major variables contributing to WL's functional performance and acceptability. Out of the 51 enrolled participants, 31 women completed the required surveys. WL's total clinical failure rate was 2.60% (out of 155 condom uses) with above-average ratings of functional performance. The ease of use significantly correlated with ratings of no slippage and no misdirection. The confidence in WL's safety features significantly correlated with a sense of empowerment and protection. WL has a relatively low risk of clinical failures and an overall favorable acceptability among Malaysian women. However, this study also showed that its future usage largely depends on partner acceptability. It may have the potential of complementing the existing barrier toward contraceptive use. Further studies are needed to understand the global acceptability of WL.

  17. A Comparison of Systematic Desensitization and Directed Masturbation in the Treatment of Primary Orgasmic Dysfunction in Females

    Science.gov (United States)

    Andersen, Barbara L.

    2009-01-01

    Thirty subjects seeking treatment for primary inorgasmia accompanied by sexual anxiety or aversion were assigned to one of three groups: systematic desensitization (SD), directed masturbation (DM), or waiting list control (WL). Following treatment, subjects were retested, and the WL group then received directed masturbation treatment. A third testing constituted a follow-up for the SD and DM groups and a posttreatment testing for the WL. Both treatments were equally effective in improving subjects’ sexual self-acceptance and increasing sexual pleasure. Changes in anxiety were negligible; however, sexual arousal and orgasm for DM and WL subjects increased. The gains of the WL group not only replicated the findings of the DM group but also were of greater magnitude. PMID:6114968

  18. Comparison of tentative radiographic working length with and without grid versus electronic apex locator

    Directory of Open Access Journals (Sweden)

    Tanikonda Rambabu

    2018-01-01

    Full Text Available The apical termination of obturation is the most important factor influencing the success of root canal treatment (RCT. Working length (WL is the key element in achieving this. Aim: The aim of this study is to compare and evaluate the preoperative estimated WL with conventional radiograph and with grid radiograph, with reference to electronic apex locator (EAL in single-rooted teeth. Settings and Design: Thirty permanent anterior teeth with complete root formation indicated for RCT were included in this study. Materials and Methods: Conventional radiograph (Group 1 and conventional radiograph with external grid (Group 2 were made before access opening. WL with EAL (Group 3 was determined after access opening. Statistical Analysis: The statistical package for the social sciences (SPSS version 16.0 (SPSS Inc., Chicago, IL, USA was used to compare the WLs of three groups, and the statistical significance was considered to be P ≤ 0.05. ANOVA, post hoc test were made to measure the intergroup comparison, and Pearson correlation values were obtained. Results and Conclusion: The results of the study showed a higher correlation between grid WL and apex locator WL than conventional WL and apex locator WL. Preoperative metrics with radiographic grid along with the apex locator is a better measuring tool compared to the conventional radiographic WL in a single-rooted tooth.

  19. Does high location and thickness of the Wrisberg ligament affect discoid lateral meniscus tear type based on peripheral detachment?

    Science.gov (United States)

    Ahn, Jin Hwan; Wang, Joon Ho; Kim, Dong Uk; Lee, Do Kyung; Kim, Jun Ho

    2017-12-01

    The aim of this study was to evaluate the relationship between discoid lateral meniscus (DLM) types based on peripheral detachment and anatomic features of Wrisberg ligament (WL) such as location and thickness based on magnetic resonance image (MRI). A total of 322 knees in 292 patients were reviewed. Patients were divided into four DLM types according to peripheral detachment: no shift (type 1), anterocentral shift (type 2), posterocentral shift (type 3) and central shift (type 4). We reviewed all MRI concentrating on the presence, location (high or low location), running angle, thickness of WL, and WL/posterior cruciate ligament (PCL) thickness ratio. The relationship between DLM types and anatomic features of WL were analyzed using one-way analysis of variance and chi-square test. According to DLM types based on peripheral detachment, 149 knees were type 1, 38 were type 2, 79 were type 3, and 56 were type 4. Among the 322 knees, 302 (93.8%) had WL on MRI. In DLM patients, type 3 showed a statistically significant (Plocation of WL. In addition, type 3 had significantly larger (Plocation and thick WL are related to posterocentral shift type of DLM based on peripheral detachment. Based on our results, the high location and thick WL might provide information to surgeons in predicting the direction of peripheral detachment in symptomatic DLM patients. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Cerebellar infarct patterns: The SMART-Medea study

    Directory of Open Access Journals (Sweden)

    Laurens J.L. De Cocker, MD

    2015-01-01

    Conclusions: Small cerebellar infarcts proved to be much more common than larger infarcts, and preferentially involved the cortex. Small cortical infarcts predominantly involved the posterior lobes, showed sparing of subcortical white matter and occurred in characteristic topographic patterns.

  1. Clinical relevance of narrow-band imaging in flexible cystoscopy

    DEFF Research Database (Denmark)

    Drejer, Ditte; Béji, Sami; Munk Nielsen, Anna

    2017-01-01

    urological departments. Patients had either hematuria (n = 483) or known recurrent non-muscle-invasive bladder cancer (NMIBC) (n = 472). High-definition (HD) cystoscopy was performed in white light (WL) and a preliminary clinical decision was made. Then, a second cystoscopy was performed in NBI...... in NBI compared to WL (NBI: 100.0% vs WL: 83.2%, p decision making as a supplement to WL because it yields a significantly higher...... and a conclusive clinical decision was made. A difference between the two decisions that had a clinical impact on the patient was considered clinically relevant. RESULTS: Pathology was found in 216 WL cystoscopies, and additional pathology in 15 NBI cystoscopies (6.9%). Based on NBI, pathology was suspected in 23...

  2. Clinical classification of cancer cachexia: phenotypic correlates in human skeletal muscle.

    Directory of Open Access Journals (Sweden)

    Neil Johns

    Full Text Available BACKGROUND: Cachexia affects the majority of patients with advanced cancer and is associated with a reduction in treatment tolerance, response to therapy, and duration of survival. One impediment towards the effective treatment of cachexia is a validated classification system. METHODS: 41 patients with resectable upper gastrointestinal (GI or pancreatic cancer underwent characterisation for cachexia based on weight-loss (WL and/or low muscularity (LM. Four diagnostic criteria were used >5%WL, >10%WL, LM, and LM+>2%WL. All patients underwent biopsy of the rectus muscle. Analysis included immunohistochemistry for fibre size and type, protein and nucleic acid concentration, Western blots for markers of autophagy, SMAD signalling, and inflammation. FINDINGS: Compared with non-cachectic cancer patients, patients with LM or LM+>2%WL, mean muscle fibre diameter was reduced by about 25% (p = 0.02 and p = 0.001 respectively. No significant difference in fibre diameter was observed if patients had WL alone. Regardless of classification, there was no difference in fibre number or proportion of fibre type across all myosin heavy chain isoforms. Mean muscle protein content was reduced and the ratio of RNA/DNA decreased in patients with either >5%WL or LM+>2%WL. Compared with non-cachectic patients, SMAD3 protein levels were increased in patients with >5%WL (p = 0.022 and with >10%WL, beclin (p = 0.05 and ATG5 (p = 0.01 protein levels were increased. There were no differences in phospho-NFkB or phospho-STAT3 levels across any of the groups. CONCLUSION: Muscle fibre size, biochemical composition and pathway phenotype can vary according to whether the diagnostic criteria for cachexia are based on weight loss alone, a measure of low muscularity alone or a combination of the two. For intervention trials where the primary end-point is a change in muscle mass or function, use of combined diagnostic criteria may allow identification of a more

  3. The influence of a Si cap on self-organized SiGe islands and the underlying wetting layer

    International Nuclear Information System (INIS)

    Brehm, M.; Grydlik, M.; Groiss, H.; Hackl, F.; Schaeffler, F.; Fromherz, T.; Bauer, G.

    2011-01-01

    For the prototypical SiGe/Si(001) Stranski-Krastanow (SK) growth system, the influence of intermixing caused by the deposition of a Si cap layer at temperatures T cap between 300 deg. C and 700 deg. C is studied both for the SiGe wetting layer (WL) and the SiGe islands. Systematic growth experiments were carried out with an ultrahigh resolution of down to 0.005 monolayers (ML) of deposited Ge. The properties of the samples were investigated via photoluminescence (PL) spectroscopy, atomic force microscopy (AFM), and transmission electron microscopy. We studied in detail the influence of T cap in the three main coverage regions of SiGe SK growth, which are (i) the WL build-up regime, (ii) the island nucleation regime, where most of the Ge is supplied via material transfer from the WL, and (iii) the saturation regime, where the WL thickness remains initially stable. At T cap = 300 deg. C, we found that both the WL and the island are essentially preserved in composition and shape, whereas at 500 deg. C the WL becomes heavily alloyed during capping, and at 700 deg. C the islands also become alloyed. At T cap = 500 deg. C we found enhanced WL intermixing in the presence of dome-shaped islands, whereas at T cap 700 deg. C the WL properties become dominated by the dissolution of pyramid-shaped islands upon capping. At Ge coverages above ≅6 ML, we found an unexpected thickening of the WL, almost independently of T cap . This finding suggests that the density and the volume of the dome-shaped islands have an upper limit, beyond which excess Ge from the external source again becomes incorporated into the WL. Finally, we compared PL spectra with AFM-based evaluations of the integral island volumes in order to determine in a straightforward manner the average composition of the SiGe islands.

  4. Weight loss versus muscle loss: re-evaluating inclusion criteria for future cancer cachexia interventional trials.

    Science.gov (United States)

    Roeland, Eric J; Ma, Joseph D; Nelson, Sandahl H; Seibert, Tyler; Heavey, Sean; Revta, Carolyn; Gallivan, Andrea; Baracos, Vickie E

    2017-02-01

    Participation in cancer cachexia clinical trials requires a defined weight loss (WL) over time. A loss in skeletal muscle mass, measured by cross-sectional computed tomography (CT) image analysis, represents a possible alternative. Our aim was to compare WL versus muscle loss in patients who were screened to participate in a cancer cachexia clinical trial. This was a single-center, retrospective analysis in metastatic colorectal cancer patients screened for an interventional cancer cachexia trial requiring a ≥5 % WL over the preceding 6 months. Concurrent CT images obtained as part of standard oncology care were analyzed for changes in total muscle and fat (visceral, subcutaneous, and total). Of patients screened (n = 36), 3 (8 %) enrolled in the trial, 17 (47 %) were excluded due to insufficient WL (20 %), and 16 (44 %) met inclusion criteria for WL. Patients who met screening criteria for WL (5-20 %) had a mean ± SD of 7.7 ± 8.7 % muscle loss, 24.4 ± 37.5 % visceral adipose loss, 21.6 ± 22.3 % subcutaneous adipose loss, and 22.1 ± 24.7 % total adipose loss. Patients excluded due to insufficient WL had 2 ± 6.4 % muscle loss, but a gain of 8.5 ± 39.8 % visceral adipose, and 4.2 ± 28.2 % subcutaneous adipose loss and 0.8 ± 28.4 % total adipose loss. Of the patients excluded due to WL 5 %. Defining cancer cachexia by WL over time may be limited as it does not capture skeletal muscle loss. Cross-sectional CT body composition analysis may improve early detection of muscle loss and patient participation in future cancer cachexia clinical trials.

  5. Effect of Exercise Type During Intentional Weight Loss on Body Composition in Older Adults with Obesity.

    Science.gov (United States)

    Beavers, Kristen M; Ambrosius, Walter T; Rejeski, W Jack; Burdette, Jonathan H; Walkup, Michael P; Sheedy, Jessica L; Nesbit, Beverly A; Gaukstern, Jill E; Nicklas, Barbara J; Marsh, Anthony P

    2017-11-01

    To examine the long-term effects of exercise modality during weight loss on body composition and associations between body composition and physical function changes. Two hundred forty-nine older adults (66.9 ± 4.7 years, 71% women, 32% African American, BMI: 34.4 ± 3.7 kg/m 2 ) were randomized to weight loss (WL; n = 82), WL plus aerobic training (WL + AT; n = 86), or WL plus resistance training (WL + RT; n = 81) for 18 months. Dual-energy x-ray absorptiometry-acquired body composition, 400-m walk time, and knee extensor strength were measured at baseline and at 6 and 18 months. Total body mass loss was enhanced when WL was combined with exercise (WL: -5.7 ± 0.7 kg, WL + AT: -8.5 ± 0.7 kg, WL + RT: -8.7 ± 0.7 kg; P exercise yields greater fat mass loss than WL alone. © 2017 The Obesity Society.

  6. Measurement of radon and thoron progenies in Coimbatore

    International Nuclear Information System (INIS)

    Sivakumar, R.; Selvasekarapandian, S.; Mahendraprasad, M.; Meenakshisundaram, V.; Santhanam, R.; Raghunath, V.M.

    2001-01-01

    The radon and thoron daughter concentrations have been measured in different dwellings of Coimbatore city by grab sampling method and two count. It has been found that the radon daughter concentration varies from 0.5 to 10.5 mWL with mean value of 2.9 mWL and that of thoron progeny is from 0.7 to 16.3 mWL with mean value of 3.8 mWL. The average annual effective dose equivalent due to radon daughters is found to be 1.3 mSv and that of thoron progeny is 3.8 mSv. (author)

  7. Relating physician's workload with errors during radiation therapy planning.

    Science.gov (United States)

    Mazur, Lukasz M; Mosaly, Prithima R; Hoyle, Lesley M; Jones, Ellen L; Chera, Bhishamjit S; Marks, Lawrence B

    2014-01-01

    To relate subjective workload (WL) levels to errors for routine clinical tasks. Nine physicians (4 faculty and 5 residents) each performed 3 radiation therapy planning cases. The WL levels were subjectively assessed using National Aeronautics and Space Administration Task Load Index (NASA-TLX). Individual performance was assessed objectively based on the severity grade of errors. The relationship between the WL and performance was assessed via ordinal logistic regression. There was an increased rate of severity grade of errors with increasing WL (P value = .02). As the majority of the higher NASA-TLX scores, and the majority of the performance errors were in the residents, our findings are likely most pertinent to radiation oncology centers with training programs. WL levels may be an important factor contributing to errors during radiation therapy planning tasks. Published by Elsevier Inc.

  8. Comparative evaluation of adequacy of final working length after using Raypex5 or radiography: An in vivo study

    Directory of Open Access Journals (Sweden)

    Deepika Singh

    2015-01-01

    Full Text Available Aim: The aim of this clinical study was to compare the effect of working length (WL determination using electronic apex locator (EAL or WL radiograph on the length adequacy of final WL. Materials and Methods: A total of 153 patients with 153 teeth with single canal were randomized into two groups; in Group 1, the WL was determined by WL radiograph; whereas in Group 2, it was determined by the Raypex5 EAL (VDW, Munich, Germany. Length adequacy was assessed in each group for master cone and categorized into short, acceptable, and over cases. Statistical Analysis Used: The data were statistically analyzed using the Pearson chi-square test at a significance level of P < 0.05. Results: There was no statistically significant difference between the groups in the rates of acceptable (Group 1 = 83.1% and Group 2 = 92.1% and short cases (Group 1 = 3.9% and Group 2 = 5.2%. Over cases in master cone radiography were significantly more in Group 1 (13.1% than Group 2 (2.6% (P = 0.017. Conclusion: The results of our study have shown that under clinical condition, success of Raypex5 was comparable to the radiographic WL determination technique in terms of acceptable and short cases. However, there were significantly lesser over cases in EAL group, showing that EALs can avoid the overestimation of WL.

  9. MRI of acute cervical injury: correlation with neurologic deficit

    International Nuclear Information System (INIS)

    Hyun, Chang Dong; Kwon, Soon Tae; Lim, Seung Chul; Shin, Myung Jin; Han, Boo Kyung; Kim, Sang Joon; Park, Man Soo; Yoon, Hyun Ki; Suh, Dae Chul

    1995-01-01

    To evaluate MRI findings of spinal cord according to mechanism in acute cervical spinal injury. 25 patients under went MRI within 1 month after acute cervical trauma. Axial T1Wl (TR/TE: 500/20), gradient-echo (TR/TE: 300/14), sagittal T1Wl (TR/TE: 500/20), proton (TR/TE: 2000. 20 msec), T2Wl (TR/TE: 2000/80) were performed. In 11 patients, post-enhancement T1Wl was done. Change of spinal cord signal intensity on MRI in addition to the presence of abnormal changes of vertebral body, intervertebral disc and paraspinal soft tissue were evaluated. 15 patients had flexion injury, seven had extension injury and three had injury of unknown mechanism. Twelve patients showed iso-signal intensity on T2Wl and high signal intensity on T2Wl. Three patients showed low signal intensity on T1Wl and high signal intensity on T2Wl. Spinal cord hemorrhage occured in 10 patients. We found cord swelling in nine patients and cord compression in 12 patients. In nine patients with cord swelling, extent of cord injury was more than one segment of vertebral body. Ligamentous injury, disc injury, soft tissue injury occurred in 16 (64%), 17 (68%), 15 (60%) patients respectively. Vertebral body fracture was found in 17 patients (68%). The levels of fracture were C6 (eight patients) and C5 (five patients). MRI is valuable in exaluetion of the spinal cord, intervertebral disc, and soft tissue lesions in acute cervical spinal injury. Prognosis is worse in flexion injury than in extension injury, and is well correlated with cord hemorrhage and lesion extent

  10. Mutations in the maize zeta-carotene desaturase gene lead to viviparous kernel.

    Directory of Open Access Journals (Sweden)

    Yan Chen

    Full Text Available Preharvest sprouting reduces the maize quality and causes a significant yield loss in maize production. vp-wl2 is a Mutator (Mu-induced viviparous mutant in maize, causing white or pale yellow kernels, dramatically reduced carotenoid and ABA content, and a high level of zeta-carotene accumulation. Here, we reported the cloning of the vp-wl2 gene using a modified digestion-ligation-amplification method (DLA. The results showed that an insertion of Mu9 in the first intron of the zeta-carotene desaturase (ZDS gene results in the vp-wl2 mutation. Previous studies have suggested that ZDS is likely the structural gene of the viviparous9 (vp9 locus. Therefore, we performed an allelic test using vp-wl2 and three vp9 mutants. The results showed that vp-wl2 is a novel allele of the vp9 locus. In addition, the sequences of ZDS gene were identified in these three vp9 alleles. The vp-wl2 mutant gene was subsequently introgressed into four maize inbred lines, and a viviparous phenotype was observed with yield losses from 7.69% to 13.33%.

  11. Optical and micro-structural characterizations of MBE grown indium gallium nitride polar quantum dots

    KAUST Repository

    Elafandy, Rami T.

    2011-12-01

    Comparison between indium rich (27%) InGaN/GaN quantum dots (QDs) and their underlying wetting layer (WL) is performed by means of optical and structural characterizations. With increasing temperature, micro-photoluminescence (μPL) study reveals the superior ability of QDs to prevent carrier thermalization to nearby traps compared to the two dimensional WL. Thus, explaining the higher internal quantum efficiency of the QD nanostructure compared to the higher dimensional WL. Structural characterization (X-ray diffraction (XRD)) and transmission electron microscopy (TEM)) reveal an increase in the QD indium content over the WL indium content which is due to strain induced drifts. © 2011 IEEE.

  12. Carbon dynamics in peatlands under changing hydrology. Effects of water level drawdown on litter quality, microbial enzyme activities and litter decomposition rates

    Energy Technology Data Exchange (ETDEWEB)

    Strakova, P.

    2010-07-01

    Pristine peatlands are carbon (C) accumulating wetland ecosystems sustained by a high water level (WL) and consequent anoxia that slows down decomposition. Persistent WL drawdown as a response to climate and/or land-use change directly affects decomposition: increased oxygenation stimulates decomposition of the 'old C' (peat) sequestered under prior anoxic conditions. Responses of the 'new C' (plant litter) in terms of quality, production and decomposability, and the consequences for the whole C cycle of peatlands are not fully understood. WL drawdown induces changes in plant community resulting in shift in dominance from Sphagnum and graminoids to shrubs and trees. There is increasing evidence that the indirect effects of WL drawdown via the changes in plant communities will have more impact on the ecosystem C cycling than any direct effects. The aim of this study is to disentangle the direct and indirect effects of WL drawdown on the 'new C' by measuring the relative importance of (1) environmental parameters (WL depth, temperature, soil chemistry) and (2) plant community composition on litter production, microbial activity, litter decomposition rates and, consequently, on the C accumulation. This information is crucial for modelling C cycle under changing climate and/or land-use. The effects of WL drawdown were tested in a large-scale experiment with manipulated WL at two time scales and three nutrient regimes. Furthermore, the effect of climate on litter decomposability was tested along a north-south gradient. Additionally, a novel method for estimating litter chemical quality and decomposability was explored by combining Near infrared spectroscopy with multivariate modelling. WL drawdown had direct effects on litter quality, microbial community composition and activity and litter decomposition rates. However, the direct effects of WL drawdown were overruled by the indirect effects via changes in litter type composition and

  13. Phase II prospective randomized trial of weight loss prior to radical prostatectomy.

    Science.gov (United States)

    Henning, Susanne M; Galet, Colette; Gollapudi, Kiran; Byrd, Joshua B; Liang, Pei; Li, Zhaoping; Grogan, Tristan; Elashoff, David; Magyar, Clara E; Said, Jonathan; Cohen, Pinchas; Aronson, William J

    2017-12-04

    Obesity is associated with poorly differentiated and advanced prostate cancer and increased mortality. In preclinical models, caloric restriction delays prostate cancer progression and prolongs survival. We sought to determine if weight loss (WL) in men with prostate cancer prior to radical prostatectomy affects tumor apoptosis and proliferation, and if WL effects other metabolic biomarkers. In this Phase II prospective trial, overweight and obese men scheduled for radical prostatectomy were randomized to a 5-8 week WL program consisting of standard structured energy-restricted meal plans (1200-1500 Kcal/day) and physical activity or to a control group. The primary endpoint was apoptotic index in the radical prostatectomy malignant epithelium. Secondary endpoints were proliferation (Ki67) in the radical prostatectomy tissue, body weight, body mass index (BMI), waist to hip ratio, body composition, and serum PSA, insulin, triglyceride, cholesterol, testosterone, estradiol, leptin, adiponectin, interleukin 6, interleukin 8, insulin-like growth factor 1, and IGF binding protein 1. In total 23 patients were randomized to the WL intervention and 21 patients to the control group. Subjects in the intervention group had significantly more weight loss (WL:-3.7 ± 0.5 kg; Control:-1.6 ± 0.5 kg; p = 0.007) than the control group and total fat mass was significantly reduced (WL:-2.1 ± 0.4; Control: 0.1 ± 0.3; p = 0.015). There was no significant difference in apoptotic or proliferation index between the groups. Among the other biomarkers, triglyceride, and insulin levels were significantly decreased in the WL compared with the control group. In summary, this short-term WL program prior to radical prostatectomy resulted in significantly more WL in the intervention vs. the control group and was accompanied by significant reductions in body fat mass, circulating triglycerides, and insulin. However, no significant changes were observed in malignant

  14. Household expenditures on dietary supplements sold for weight loss, muscle building, and sexual function: Disproportionate burden by gender and income.

    Science.gov (United States)

    Austin, S Bryn; Yu, Kimberly; Liu, Selena Hua; Dong, Fan; Tefft, Nathan

    2017-06-01

    Dietary supplements sold for weight loss (WL), muscle building (MB), and sexual function (SF) are not medically recommended. They have been shown to be ineffective in many cases and pose serious health risks to consumers due to adulteration with banned substances, prescription pharmaceuticals, and other dangerous chemicals. Yet no prior research has investigated how these products may disproportionately burden individuals and families by gender and socioeconomic position across households. We investigated household (HH) cost burden of dietary supplements sold for WL, MB, and SF in a cross-sectional study using data from 60,538 U.S. households (HH) in 2012 Nielsen/IRi National Consumer Panel, calculating annual HH expenditures on WL, MB, and SF supplements and expenditures as proportions of total annual HH income. We examined sociodemographic patterns in HH expenditures using Wald tests of mean differences across subgroups. Among HH with any expenditures on WL, MB, or SF supplements, annual HH first and ninth expenditure deciles were, respectively: WL $5.99, $145.36; MB $6.99, $141.93; and SF $4.98, $88.52. Conditional on any purchases of the products, female-male-headed HH spent more on WL supplements and male-headed HH spend more on MB and SF supplements compared to other HH types ( p -values supplements types ( p -values supplements ( p -values supplements sold for WL, MB, and SF disproportionately burden HH by income and gender.

  15. Impact of weight loss achieved through a multidisciplinary intervention on appetite in patients with severe obesity

    DEFF Research Database (Denmark)

    Coutinho, Silvia R; Rehfeld, Jens F; Holst, Jens J

    2018-01-01

    The impact of lifestyle-induced weight loss (WL) on appetite in patients with obesity remains controversial. This study aimed was to assess the short- and long-term impact of WL achieved by diet and exercise, on appetite in patients with obesity. Thirty-five (22 females) adults with severe obesity......), in the fasting and postprandial states, were measured at baseline (B), week 4 (W4), 1 and 2-years (and average values for all fasting and postprandial time points computed). BW was significantly reduced and VO2max (ml/kg/min) increased at all time points compared with B (3.5, 8.1 and 8.4 % WL and 7, 11 and 8...... compared with B. Average GLP-1 was reduced at W4 and CCK increased at 2y. After lifestyle-induced WL, patients with severe obesity will, therefore, have to deal with increased hunger in the long-term. In conclusion, sustained WL at 2y achieved with diet and exercise is associated with increased hunger...

  16. Impact of Weight Change During the Course of Concurrent Chemoradiation Therapy on Outcomes in Stage IIIB Non-Small Cell Lung Cancer Patients: Retrospective Analysis of 425 Patients

    International Nuclear Information System (INIS)

    Topkan, Erkan; Parlak, Cem; Selek, Ugur

    2013-01-01

    Purpose: We retrospectively investigated the impact of weight change (WC) during concurrent chemoradiation therapy (C-CRT) on clinical outcomes of stage 3B non-small cell lung cancer (NSCLC) patients. Methods and Materials: A total of 425 patients treated with C-CRT were included. All patients received 60 to 66 Gy of thoracic radiation therapy concurrently with 1 to 3 cycles of platinum-based chemotherapy. Pre- and posttreatment weight measurements on first and last days of C-CRT were used for WC. Patients were divided into 2 groups: group 1 = weight loss (WL); group 2 = weight preservation/gain (WP) for comparative analyses. Results: Following C-CRT, 252 patients (59.3%) experienced WL, while 89 patients (20.9%) and 84 patients (19.8%) showed WP or WG. At median 24.2 months of follow-up, 142 patients (33.4%) were alive (84 WP [48.6%] and 58 WL [23.0%]), and 58 (13.6%) of them were free of disease progression (41 [23.7%] for WP and 17 [6.7%] for WL). Median overall survival (OS), locoregional progression-free survival (LRPFS), progression-free survival (PFS), and distant metastases-free survival (DMFS) for the entire population were 22.8, 14.4, 10.6, and 11.7 months, respectively. Intergroup comparisons between WP and WL cohorts revealed significantly superior OS, LRPFS, PFS, and DMFS in WP patients (P<.05 for each). On multivariate analyses, only WL and advanced T stage were associated with poor prognosis (P<.05). Conclusions: Present results in 425 stage 3B NSCLC patients demonstrated that WL during C-CRT is strongly associated with inferior survival outcomes compared to WP. This emerging finding might be useful by forming an encouraging basis for future investigations in facilitating a way to improve the outcomes of these patients experiencing WL during C-CRT

  17. Prospective Out-of-ecliptic White-light Imaging of Interplanetary Corotating Interaction Regions at Solar Maximum

    Energy Technology Data Exchange (ETDEWEB)

    Xiong, Ming; Yang, Liping; Liu, Ying D.; Keiji, Hayashi; Li, Huichao [State Key Laboratory of Space Weather, National Space Science Center, Chinese Academy of Sciences, Beijing (China); Davies, Jackie A.; Harrison, Richard A. [RAL Space, STFC-Rutherford Appleton Laboratory, Harwell Campus, Didcot (United Kingdom); Li, Bo; Xia, Lidong, E-mail: mxiong@spacweather.ac.cn [Shandong Provincial Key Laboratory of Optical Astronomy and Solar-Terrestrial Environment, Institute of Space Sciences, Shandong University, Weihai (China)

    2017-07-20

    Interplanetary corotating interaction regions (CIRs) can be remotely imaged in white light (WL), as demonstrated by the Solar Mass Ejection Imager (SMEI) on board the Coriolis spacecraft and Heliospheric Imagers (HIs) on board the twin Solar TErrestrial RElations Observatory ( STEREO ) spacecraft. The interplanetary WL intensity, due to Thomson scattering of incident sunlight by free electrons, is jointly determined by the 3D distribution of electron number density and line-of-sight (LOS) weighting factors of the Thomson-scattering geometry. The 2D radiance patterns of CIRs in WL sky maps look very different from different 3D viewpoints. Because of the in-ecliptic locations of both the STEREO and Coriolis spacecraft, the longitudinal dimension of interplanetary CIRs has, up to now, always been integrated in WL imagery. To synthesize the WL radiance patterns of CIRs from an out-of-ecliptic (OOE) vantage point, we perform forward magnetohydrodynamic modeling of the 3D inner heliosphere during Carrington Rotation CR1967 at solar maximum. The mixing effects associated with viewing 3D CIRs are significantly minimized from an OOE viewpoint. Our forward modeling results demonstrate that OOE WL imaging from a latitude greater than 60° can (1) enable the garden-hose spiral morphology of CIRs to be readily resolved, (2) enable multiple coexisting CIRs to be differentiated, and (3) enable the continuous tracing of any interplanetary CIR back toward its coronal source. In particular, an OOE view in WL can reveal where nascent CIRs are formed in the extended corona and how these CIRs develop in interplanetary space. Therefore, a panoramic view from a suite of wide-field WL imagers in a solar polar orbit would be invaluable in unambiguously resolving the large-scale longitudinal structure of CIRs in the 3D inner heliosphere.

  18. Wobbling and LSF-based maximum likelihood expectation maximization reconstruction for wobbling PET

    International Nuclear Information System (INIS)

    Kim, Hang-Keun; Son, Young-Don; Kwon, Dae-Hyuk; Joo, Yohan; Cho, Zang-Hee

    2016-01-01

    Positron emission tomography (PET) is a widely used imaging modality; however, the PET spatial resolution is not yet satisfactory for precise anatomical localization of molecular activities. Detector size is the most important factor because it determines the intrinsic resolution, which is approximately half of the detector size and determines the ultimate PET resolution. Detector size, however, cannot be made too small because both the decreased detection efficiency and the increased septal penetration effect degrade the image quality. A wobbling and line spread function (LSF)-based maximum likelihood expectation maximization (WL-MLEM) algorithm, which combined the MLEM iterative reconstruction algorithm with wobbled sampling and LSF-based deconvolution using the system matrix, was proposed for improving the spatial resolution of PET without reducing the scintillator or detector size. The new algorithm was evaluated using a simulation, and its performance was compared with that of the existing algorithms, such as conventional MLEM and LSF-based MLEM. Simulations demonstrated that the WL-MLEM algorithm yielded higher spatial resolution and image quality than the existing algorithms. The WL-MLEM algorithm with wobbling PET yielded substantially improved resolution compared with conventional algorithms with stationary PET. The algorithm can be easily extended to other iterative reconstruction algorithms, such as maximum a priori (MAP) and ordered subset expectation maximization (OSEM). The WL-MLEM algorithm with wobbling PET may offer improvements in both sensitivity and resolution, the two most sought-after features in PET design. - Highlights: • This paper proposed WL-MLEM algorithm for PET and demonstrated its performance. • WL-MLEM algorithm effectively combined wobbling and line spread function based MLEM. • WL-MLEM provided improvements in the spatial resolution and the PET image quality. • WL-MLEM can be easily extended to the other iterative

  19. Effects of weight loss and exercise on trunk muscle composition in older women

    Directory of Open Access Journals (Sweden)

    Ryan AS

    2014-03-01

    Full Text Available Alice S Ryan, Aruna Selina Harduarsingh-Permaul Baltimore Veterans Affairs Medical Center; Gerontology and Geriatric Medicine, School of Medicine, University of Maryland; Baltimore Geriatric Research Education and Clinical Center (GRECC, and Research and Development Service, VA Maryland Health Care System, Baltimore, MD, USA Background: Aging and obesity increase the risk for mobility limitations in women. Although trunk muscle composition is important to physical function, the implication of ectopic fat in the trunk muscles with respect to physical fitness and its potential for modification by lifestyle changes is unknown. Methods: The effects of a 6-month period of either weight loss (WL alone or of aerobic exercise (AEX plus WL (AEX+WL, on trunk body composition, as measured by dual-energy X-ray absorptiometry (DXA (to measure trunk fat and lean mass and computed tomography (CT (to measure the erector spinae, psoas, lateral abdominal, rectus abdominis muscle, and intramuscular fat, and the intramuscular adipose tissue [IMAT] areas was determined in 65 overweight and obese postmenopausal women (aged 50-76 years. Results: The area of the erector spinae, psoas, and rectus abdominis muscles declined with age in the women (P<0.05. Both the spinal and abdominal muscle areas were related to the maximal oxygen uptake (VO2max (P<0.05. Body weight decreased by 8% after both AEX+WL and WL (P<0.001. The VO2max increased by 11% after AEX+WL (P<0.001 but did not change with WL alone (group effect, P<0.001. The DXA-measured trunk fat mass decreased by 16% after AEX+WL (P<0.001 and by 12% after WL (P<0.001. When both groups were combined, the IMAT decreased in all four muscle groups - by 6% in the erector spinae (P<0.01, by 9% in the psoas (P<0.01, by 11% in the lateral abdominals (P<0.001, and by 6% in the rectus abdominis (P<0.05. The loss of fat mass was related to the loss of IMAT of the erector spinae and the lateral abdominals. Conclusions: A lifestyle

  20. Study of indoor radon, thoron and their progeny concentration levels in the surrounding areas of Mangaldoi, Assam

    International Nuclear Information System (INIS)

    Deka, P.C.; Sarkar, S.; Goswami, T.D.; Sarma, B.K.

    2006-01-01

    Natural sources contribute a significant percentage of radiation towards the total radiation exposure that humans receive. The majority of this natural radiation is harmless to humans in the ambient environment. However, radon, a major component of the natural radiation that humans are exposed to (greater than sixty percent), can pose a threat to the public health when radon gas accumulates in poorly ventilated residential and occupational settings. Measurements of concentration of radon, thoron and their decay products in various indoor environment covering four seasons of a year were carried out using the passive time-integrated method by employing LR-15 type II detectors in plastic twin-chamber dosimeter cups. The estimated indoor radon levels for well ventilated houses varied from a minimum value of 25.2 Bq.m -3 to a maximum of 80J Bq.m -3 with an annual geometric mean of 46.9 Bq.m -3 and that for poorly ventilated houses varied from a minimum value of 46.8 Bq.m -3 to a maximum of 146.8 Bq.m -3 with the annual geometric mean of 82 .2 Bq.m -3 . The thoron levels in well ventilated houses were also varied from a minimum value of 4.9 Bq.m -3 to a maximum of 21.5 Bq.m -3 with an annual geometric mean of 10.5 Bq.m -3 and that for poorly ventilated houses varied from a minimum of 6.3 Bq.m -3 to a maximum value of 29.2 Bq.m -3 with the annual geometric mean of 14.1 Bq.m -3 . Thus it is seen that both radon and thoron levels are higher in poorly ventilated houses than in well-ventilated houses. The ranges of radon and thoron progeny levels for well ventilated houses were 0.10 mWL to 0.58 mWL with an annual geometric mean of 0.21 mWL and 0.01 mWL to 0.06 mWL with an annual geometric mean of 0.03 mWL respectively. Similar variation was also observed in poorly ventilated houses. In poorly ventilated houses, the radon and thoron progeny levels varied between 0.16 mWL and 1.61 mWL with an annual geometric mean of 0.41 mWL and 0.02 to 029 mWL with the annual geometric mean

  1. Improvements in insulin sensitivity after aerobic exercise and weight loss in older women with a history of gestational diabetes and type 2 diabetes mellitus.

    Science.gov (United States)

    Ryan, Alice S

    2016-05-01

    To determine whether a hypocaloric diet alone (WL) or with exercise training (AEX + WL) is effective in improving body composition, fitness, glucose utilization and CVD risk factors in sedentary women with a history of gestational diabetes (GDM) and with type 2 diabetes (T2DM). Longitudinal clinical investigation of 25 overweight/obese (BMI: 32 ± 1 kg/m(2)) women (59 ± 1 yrs) with a GDM history (n = 20) or T2DM (n = 5). Women completed 6 months WL (n = 10) or AEX+WL (n = 15) with VO2max, body composition, and glucose tolerance testing. Insulin sensitivity was measured during the last 30 min of 2 h hyperinsulinemic-euglycemic clamps (40 mU·m(-2.)min(-1)) before and after interventions. Body weight decreased ~7% after WL and AEX+WL (p exercise program combined with moderate weight loss reduces body weight, visceral and subcutaneous abdominal fat, and improves insulin sensitivity in older women who had previously been diagnosed with GDM and those with T2DM. These findings should encourage women with a history of GDM to engage in an active lifestyle and reduce caloric intake to lower the risk for the development of T2DM.

  2. Assessment of the Impact of Reservoirs in the Upper Mekong River Using Satellite Radar Altimetry and Remote Sensing Imageries

    Directory of Open Access Journals (Sweden)

    Kuan-Ting Liu

    2016-04-01

    Full Text Available Water level (WL and water volume (WV of surface-water bodies are among the most crucial variables used in water-resources assessment and management. They fluctuate as a result of climatic forcing, and they are considered as indicators of climatic impacts on water resources. Quantifying riverine WL and WV, however, usually requires the availability of timely and continuous in situ data, which could be a challenge for rivers in remote regions, including the Mekong River basin. As one of the most developed rivers in the world, with more than 20 dams built or under construction, Mekong River is in need of a monitoring system that could facilitate basin-scale management of water resources facing future climate change. This study used spaceborne sensors to investigate two dams in the upper Mekong River, Xiaowan and Jinghong Dams within China, to examine river flow dynamics after these dams became operational. We integrated multi-mission satellite radar altimetry (RA, Envisat and Jason-2 and Landsat-5/-7/-8 Thematic Mapper (TM/Enhanced Thematic Mapper plus (ETM+/Operational  Land Imager (OLI optical remote sensing (RS imageries to construct composite WL time series with enhanced spatial resolutions and substantially extended WL data records. An empirical relationship between WL variation and water extent was first established for each dam, and then the combined long-term WL time series from Landsat images are reconstructed for the dams. The R2 between altimetry WL and Landsat water area measurements is >0.95. Next, the Tropical Rainfall Measuring Mission (TRMM data were used to diagnose and determine water variation caused by the precipitation anomaly within the basin. Finally, the impact of hydrologic dynamics caused by the impoundment of the dams is assessed. The discrepancy between satellite-derived WL and available in situ gauge data, in term of root-mean-square error (RMSE is at 2–5 m level. The estimated WV variations derived from combined RA

  3. DETERMINATION OF FIBROMYALGIA SYNDROME FOLLOWING WHIPLASH INJURIES: METHODOLOGIC ISSUES

    Science.gov (United States)

    Robinson, James P.; Theodore, Brian R.; Wilson, Hilary D.; Waldo, Peter G.; Turk, Dennis C.

    2011-01-01

    Problems in diagnosing FM among motor vehicle collision (MVC) patients with whiplash (WL) include: the predominance of tender points (TPs) in the neck/shoulder girdle region; the 3-month duration of widespread pain criterion; and, the stability of diagnosis. The present study examined the prevalence of FM in a cohort (N = 326) with persistent neck pain 3 months following WL injury who were enrolled in a treatment program. Physical examinations were performed at baseline and at the end of treatment. Results indicated that WL patients had a greater proportion of neck/shoulder girdle TPs, relative to distal TPs. Compared to a matched cohort of treatment-seeking FM patients, WL patients indicated less distal TPs (M = 7.3 TPs vs. M = 5.6 TPs, p < 0.001), but were equivalent on neck/shoulder girdle TPs (M = 9.0 TPs vs. 9.2 TPs, ns). Baseline prevalence of FM for the WL cohort based on ACR criteria was 14% (95% CI: 10% – 18%), adjusted TP criterion discounting for neck/shoulder tenderness indicated a prevalence of FM of 8% (95% CI: 5% – 11%). Finally, 63% of patients meeting American College of Rheumatology FM criteria at baseline did not meet this criterion at post-treatment (approx. 6-months post-MVC). In conclusion, present criteria used in determining FM may result in spuriously inflated rates of diagnosis among WL patients due to persistent localized tenderness following MVC. Furthermore, the transient nature of FM “symptoms” among WL patients should be taken into account before making a final diagnosis. PMID:21419574

  4. Effect of canal length and curvature on working length alteration with WaveOne reciprocating files.

    Science.gov (United States)

    Berutti, Elio; Chiandussi, Giorgio; Paolino, Davide Salvatore; Scotti, Nicola; Cantatore, Giuseppe; Castellucci, Arnaldo; Pasqualini, Damiano

    2011-12-01

    This study evaluated the working length (WL) modification after instrumentation with WaveOne Primary (Dentsply Maillefer, Ballaigues, Switzerland) reciprocating files and the incidence of overinstrumentation in relation to the initial WL. Thirty-two root canals of permanent teeth were used. The angles of curvature of the canals were calculated on digital radiographs. The initial WL with K-files was transferred to the matched WaveOne Primary reciprocating files. After glide paths were established with PathFile (Dentsply Maillefer, Ballaigues, Switzerland), canals were shaped with WaveOne Primary referring to the initial WL. The difference between the postinstrumentation canal length and the initial canal length was analyzed by using a fiberoptic inspection microscope. Data were analyzed with a balanced 2-way factorial analysis of variance (P < .05). Referring to the initial WL, 24 of 32 WaveOne Primary files projected beyond the experimental apical foramen (minimum-maximum, 0.14-0.76 mm). A significant decrease in the canal length after instrumentation (95% confidence interval ranging from -0.34 mm to -0.26 mm) was detected. The canal curvature significantly influenced the WL variation (F(1) = 30.65, P < .001). The interaction between the initial canal length and the canal curvature was statistically significant (F(2) = 4.38, P = .014). Checking the WL before preparation of the apical third of the root canal is recommended when using the new WaveOne NiTi single-file system. Copyright © 2011 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  5. Exact exchange and Wilson-Levy correlation: a pragmatic device for studying complex weakly-bonded systems.

    Science.gov (United States)

    Walsh, T R

    2005-02-07

    The Wilson-Levy (WL) correlation functional is used together with Hartree-Fock (HF) theory to evaluate interaction energies at intermediate separations (i.e. around equilibrium separation) for several weakly-bonded systems. The HF+WL approach reproduces binding trends for all complexes studied: selected rare-gas dimers, isomers of the methane dimer, benzene dimer and naphthalene dimer, and base-pair stacking structures for pyrimidine, cytosine, uracil and guanine dimers. These HF+WL data are contrasted against results obtained from some popular functionals (including B3LYP and PBE), as well as two newly-developed functionals, X3LYP and xPBE. The utility of HF+WL, with reference to exact-exchange (EXX) density-functional theory, is discussed in terms of a suggested EXXWL exchange-correlation functional.

  6. Blind I/Q imbalance and nonlinear ISI mitigation in Nyquist-SCM direct detection system with cascaded widely linear and Volterra equalizer

    Science.gov (United States)

    Liu, Na; Ju, Cheng

    2018-02-01

    Nyquist-SCM signal after fiber transmission, direct detection (DD), and analog down-conversion suffers from linear ISI, nonlinear ISI, and I/Q imbalance, simultaneously. Theoretical analysis based on widely linear (WL) and Volterra series is given to explain the relationship and interaction of these three interferences. A blind equalization algorithm, cascaded WL and Volterra equalizer, is designed to mitigate these three interferences. Furthermore, the feasibility of the proposed cascaded algorithm is experimentally demonstrated based on a 40-Gbps data rate 16-quadrature amplitude modulation (QAM) virtual single sideband (VSSB) Nyquist-SCM DD system over 100-km standard single mode fiber (SSMF) transmission. In addition, the performances of conventional strictly linear equalizer, WL equalizer, Volterra equalizer, and cascaded WL and Volterra equalizer are experimentally evaluated, respectively.

  7. Quality of Working Life - An Exploration of Contributing Factors and their Relative Salience to Employees

    OpenAIRE

    Blackford, Katherine

    2015-01-01

    The academic study of Quality of Working Life (QoWL) has a long tradition, vestiges of which are apparent in the classic job satisfaction and employee motivation research (see for example, Mayo and Warner, 1931; Maslow, 1943; 1932; Blauner 1964; Hertzberg, 1966). The intervening years have witnessed the accumulation of a broad, complex and, at times contradictory, literature relating to variables identified as impacting on QoWL. The potential value of investing in enhancing QoWL cannot be und...

  8. Impact of Weight Loss on Physical Function with Changes in Strength, Muscle Mass, and Muscle Fat Infiltration in Overweight to Moderately Obese Older Adults: A Randomized Clinical Trial

    Directory of Open Access Journals (Sweden)

    Adam J. Santanasto

    2011-01-01

    Full Text Available Purpose. Evaluate the effects of weight loss on muscle mass and area, muscle fat infiltration, strength, and their association with physical function. Methods. Thirty-six overweight to moderately obese, sedentary older adults were randomized into either a physical activity plus weight loss (PA+WL or physical activity plus successful aging health education (PA+SA program. Measurements included body composition by dual-energy X-ray absorptiometry, computerized tomography, knee extensor strength, and short physical performance battery (SPPB. Results. At 6 months, PA+WL lost greater thigh fat and muscle area compared to PA+SA. PA+WL lost 12.4% strength; PA+SA lost 1.0%. Muscle fat infiltration decreased significantly in PA+WL and PA+SA. Thigh fat area decreased 6-fold in comparison to lean area in PA+WL. Change in total SPPB score was strongly inversely correlated with change in fat but not with change in lean or strength. Conclusion. Weight loss resulted in additional improvements in function over exercise alone, primarily due to loss of body fat.

  9. Effects of Exercise Training and Weight Loss on Plasma Fetuin-A Levels and Insulin Sensitivity in Overweight Older Men

    Directory of Open Access Journals (Sweden)

    Jacob B. Blumenthal

    2017-01-01

    Full Text Available Aerobic exercise training and weight loss (AEX+WL improves insulin sensitivity in overweight adults; however, the underlying pathways are incompletely understood. Fetuin-A, a hepatokine that inhibits insulin signaling, may be involved in the salutary effects of AEX+WL. Therefore, we examined the effects of 6-month AEX+WL on plasma fetuin-A levels (36–48 hours after the last bout of exercise, aerobic capacity (VO2max, body composition, glucose tolerance, and insulin sensitivity (M in 16 sedentary, overweight-obese older men (age = 60 ± 2 years, BMI = 31 ± 1 kg/m2 with no history of cardiovascular disease or diabetes. At baseline, fetuin-A levels correlated directly with adiposity and had a borderline inverse correlation with M. After AEX+WL, body weight decreased by ~10 kg, while both VO2max and M increased by 16% (P<0.005 for all. Contrary to our hypothesis, plasma fetuin-A levels increased after AEX+WL (1.16 ± 0.10 g/L versus 1.70 ± 0.19 g/L, P=0.006. This increase was unrelated to changes in body composition or glucose metabolism, but directly correlated with changes in VO2max (r=0.57, P<0.05. Thus, in overweight-to-obese older men, AEX+WL appears to increase plasma fetuin-A levels. Although not associated with improvements in insulin sensitivity, this increase in fetuin-A was related to improvements in aerobic capacity and could be representative of the cardioprotective effects of AEX+WL in older men.

  10. Effects of Exercise Training and Weight Loss on Plasma Fetuin-A Levels and Insulin Sensitivity in Overweight Older Men.

    Science.gov (United States)

    Blumenthal, Jacob B; Gitterman, Anna; Ryan, Alice S; Prior, Steven J

    2017-01-01

    Aerobic exercise training and weight loss (AEX+WL) improves insulin sensitivity in overweight adults; however, the underlying pathways are incompletely understood. Fetuin-A, a hepatokine that inhibits insulin signaling, may be involved in the salutary effects of AEX+WL. Therefore, we examined the effects of 6-month AEX+WL on plasma fetuin-A levels (36-48 hours after the last bout of exercise), aerobic capacity (VO 2max ), body composition, glucose tolerance, and insulin sensitivity (M) in 16 sedentary, overweight-obese older men (age = 60 ± 2 years, BMI = 31 ± 1 kg/m 2 ) with no history of cardiovascular disease or diabetes. At baseline, fetuin-A levels correlated directly with adiposity and had a borderline inverse correlation with M. After AEX+WL, body weight decreased by ~10 kg, while both VO 2max and M increased by 16% ( P < 0.005 for all). Contrary to our hypothesis, plasma fetuin-A levels increased after AEX+WL (1.16 ± 0.10 g/L versus 1.70 ± 0.19 g/L, P = 0.006). This increase was unrelated to changes in body composition or glucose metabolism, but directly correlated with changes in VO 2max ( r = 0.57, P < 0.05). Thus, in overweight-to-obese older men, AEX+WL appears to increase plasma fetuin-A levels. Although not associated with improvements in insulin sensitivity, this increase in fetuin-A was related to improvements in aerobic capacity and could be representative of the cardioprotective effects of AEX+WL in older men.

  11. Global Integration of the Hot-State Brain Network of Appetite Predicts Short Term Weight Loss in Older Adult

    Directory of Open Access Journals (Sweden)

    Brielle M Paolini

    2015-05-01

    Full Text Available Obesity is a public health crisis in North America. While lifestyle interventions for weight loss (WL remain popular, the rate of success is highly variable. Clearly, self-regulation of eating behavior is a challenge and patterns of activity across the brain may be an important determinant of success. The current study prospectively examined whether integration across the Hot-State Brain Network of Appetite (HBN-A predicts WL after 6-months of treatment in older adults. Our metric for network integration was global efficiency (GE. The present work is a sub-study (n = 56 of an ongoing randomized clinical trial involving WL. Imaging involved a baseline food-cue visualization functional MRI (fMRI scan following an overnight fast. Using graph theory to build functional brain networks, we demonstrated that regions of the HBN-A (insula, anterior cingulate cortex (ACC, superior temporal pole, amygdala and the parahippocampal gyrus were highly integrated as evidenced by the results of a principal component analysis. After accounting for known correlates of WL (baseline weight, age, sex, and self-regulatory efficacy and treatment condition, which together contributed 36.9% of the variance in WL, greater GE in the HBN-A was associated with an additional 19% of the variance. The ACC of the HBN-A was the primary driver of this effect, accounting for 14.5% of the variance in WL when entered in a stepwise regression following the covariates, p = 0.0001. The HBN-A is comprised of limbic regions important in the processing of emotions and visceral sensations and the ACC is key for translating such processing into behavioral consequences. The improved integration of these regions may enhance awareness of body and emotional states leading to more successful self-regulation and to greater WL. This is the first study among older adults to prospectively demonstrate that, following an overnight fast, GE of the HBN-A during a food visualization task is predictive of

  12. Selection for higher fertility reflects in the seminal fluid proteome of modern domestic chicken.

    Science.gov (United States)

    Atikuzzaman, Mohammad; Sanz, Libia; Pla, Davinia; Alvarez-Rodriguez, Manuel; Rubér, Marie; Wright, Dominic; Calvete, Juan J; Rodriguez-Martinez, Heriberto

    2017-03-01

    The high egg-laying capacity of the modern domestic chicken (i.e. White Leghorn, WL) has arisen from the low egg-laying ancestor Red Junglefowl (RJF) via continuous trait selection and breeding. To investigate whether this long-term selection impacted the seminal fluid (SF)-proteome, 2DE electrophoresis-based proteomic analyses and immunoassays were conducted to map SF-proteins/cytokines in RJF, WL and a 9th generation Advanced Intercross Line (AIL) of RJF/WL-L13, including individual SF (n=4, from each RJF, WL and AIL groups) and pools of the SF from 15 males of each group, analyzed by 2DE to determine their degree of intra-group (AIL, WL, and RJF) variability using Principal Component Analysis (PCA); respectively an inter-breed comparative analysis of intergroup fold change of specific SF protein spots intensity between breeds. The PCA clearly highlighted a clear intra-group similarity among individual roosters as well as a clear inter-group variability (e.g. between RJF, WL and AIL) validating the use of pools to minimize confounding individual variation. Protein expression varied considerably for processes related to sperm motility, nutrition, transport and survival in the female, including signaling towards immunomodulation. The major conserved SF-proteins were serum albumin and ovotransferrin. Aspartate aminotransferase, annexin A5, arginosuccinate synthase, glutathione S-transferase 2 and l-lactate dehydrogenase-A were RJF-specific. Glyceraldehyde-3-phosphate dehydrogenase appeared specific to the WL-SF while angiotensin-converting enzyme, γ-enolase, coagulation factor IX, fibrinogen α-chain, hemoglobin subunit α-D, lysozyme C, phosphoglycerate kinase, Src-substrate protein p85, tubulins and thioredoxin were AIL-specific. The RJF-SF contained fewer immune system process proteins and lower amounts of the anti-inflammatory/immunomodulatory TGF-β2 compared to WL and AIL, which had low levels- or lacked pro-inflammatory CXCL10 compared to RJF. The seminal

  13. Prospective Out-of-ecliptic White-light Imaging of Coronal Mass Ejections Traveling through the Corona and Heliosphere

    Science.gov (United States)

    Xiong, Ming; Davies, Jackie A.; Harrison, Richard A.; Zhou, Yufen; Feng, Xueshang; Xia, Lidong; Li, Bo; Liu, Ying D.; Hayashi, Keiji; Li, Huichao; Yang, Liping

    2018-01-01

    The in-flight performance of the Coriolis/SMEI and STEREO/HI instruments substantiates the high-technology readiness level of white-light (WL) imaging of coronal mass ejections (CMEs) in the inner heliosphere. The WL intensity of a propagating CME is jointly determined by its evolving mass distribution and the fixed Thomson-scattering geometry. From their in-ecliptic viewpoints, SMEI and HI, the only heliospheric imagers that have been flown to date, integrate the longitudinal dimension of CMEs. In this paper, using forward magnetohydrodynamic modeling, we synthesize the WL radiance pattern of a typical halo CME viewed from an out-of-ecliptic (OOE) vantage point. The major anatomical elements of the CME identified in WL imagery are a leading sheath and a trailing ejecta; the ejecta-driven sheath is the brightest feature of the CME. The sheath, a three-dimensional (3D) dome-like density structure, occupies a wide angular extent ahead of the ejecta itself. The 2D radiance pattern of the sheath depends critically on viewpoint. For a CME modeled under solar minimum conditions, the WL radiance pattern of the sheath is generally a quasi-straight band when viewed from an in-ecliptic viewpoint and a semicircular arc from an OOE viewpoint. The dependence of the radiance pattern of the ejecta-driven sheath on viewpoint is attributed to the bimodal nature of the 3D background solar wind flow. Our forward-modeling results suggest that OOE imaging in WL radiance can enable (1) a near-ecliptic CME to be continuously tracked from its coronal initiation, (2) the longitudinal span of the CME to be readily charted, and (3) the transporting speed of the CME to be reliably determined. Additional WL polarization measurements can significantly limit the ambiguity of localizing CMEs. We assert that a panoramic OOE view in WL would be highly beneficial in revealing CME morphology and kinematics in the hitherto-unresolved longitudinal dimension and hence for monitoring the propagation and

  14. Calibrating a hydraulic model using water levels derived from time series high-resolution Radarsat-2 synthetic aperture radar images and elevation data

    Science.gov (United States)

    Trudel, M.; Desrochers, N.; Leconte, R.

    2017-12-01

    Knowledge of water extent (WE) and level (WL) of rivers is necessary to calibrate and validate hydraulic models and thus to better simulate and forecast floods. Synthetic aperture radar (SAR) has demonstrated its potential for delineating water bodies, as backscattering of water is much lower than that of other natural surfaces. The ability of SAR to obtain information despite cloud cover makes it an interesting tool for temporal monitoring of water bodies. The delineation of WE combined with a high-resolution digital terrain model (DTM) allows extracting WL. However, most research using SAR data to calibrate hydraulic models has been carried out using one or two images. The objectives of this study is to use WL derived from time series high resolution Radarsat-2 SAR images for the calibration of a 1-D hydraulic model (HEC-RAS). Twenty high-resolution (5 m) Radarsat-2 images were acquired over a 40 km reach of the Athabasca River, in northern Alberta, Canada, between 2012 and 2016, covering both low and high flow regimes. A high-resolution (2m) DTM was generated combining information from LIDAR data and bathymetry acquired between 2008 and 2016 by boat surveying. The HEC-RAS model was implemented on the Athabasca River to simulate WL using cross-sections spaced by 100 m. An image histogram thresholding method was applied on each Radarsat-2 image to derive WE. WE were then compared against each cross-section to identify those were the slope of the banks is not too abrupt and therefore amenable to extract WL. 139 observations of WL at different locations along the river reach and with streamflow measurements were used to calibrate the HEC-RAS model. The RMSE between SAR-derived and simulated WL is under 0.35 m. Validation was performed using in situ observations of WL measured in 2008, 2012 and 2016. The RMSE between the simulated water levels calibrated with SAR images and in situ observations is less than 0.20 m. In addition, a critical success index (CSI) was

  15. Transmission of stress-induced learning impairment and associated brain gene expression from parents to offspring in chickens.

    Directory of Open Access Journals (Sweden)

    Christina Lindqvist

    Full Text Available BACKGROUND: Stress influences many aspects of animal behaviour and is a major factor driving populations to adapt to changing living conditions, such as during domestication. Stress can affect offspring through non-genetic mechanisms, but recent research indicates that inherited epigenetic modifications of the genome could possibly also be involved. METHODOLOGY/PRINCIPAL FINDINGS: Red junglefowl (RJF, ancestors of modern chickens and domesticated White Leghorn (WL chickens were raised in a stressful environment (unpredictable light-dark rhythm and control animals in similar pens, but on a 12/12 h light-dark rhythm. WL in both treatments had poorer spatial learning ability than RJF, and in both populations, stress caused a reduced ability to solve a spatial learning task. Offspring of stressed WL, but not RJF, raised without parental contact, had a reduced spatial learning ability compared to offspring of non-stressed animals in a similar test as that used for their parents. Offspring of stressed WL were also more competitive and grew faster than offspring of non-stressed parents. Using a whole-genome cDNA microarray, we found that in WL, the same changes in hypothalamic gene expression profile caused by stress in the parents were also found in the offspring. In offspring of stressed WL, at least 31 genes were up- or down-regulated in the hypothalamus and pituitary compared to offspring of non-stressed parents. CONCLUSIONS/SIGNIFICANCE: Our results suggest that, in WL the gene expression response to stress, as well as some behavioural stress responses, were transmitted across generations. The ability to transmit epigenetic information and behaviour modifications between generations may therefore have been favoured by domestication. The mechanisms involved remain to be investigated; epigenetic modifications could either have been inherited or acquired de novo in the specific egg environment. In both cases, this would offer a novel explanation to

  16. When Does the Warmest Water Reach Greenland?

    Science.gov (United States)

    Grist, J. P.; Josey, S. A.; Boehme, L.; Meredith, M. P.; Laidre, K. L.; Heide-Jørgensen, M. P.; Kovacs, K. M.; Lydersen, C.; Davidson, F. J. M.; Stenson, G. B.; Hammill, M. O.; Marsh, R.; Coward, A.

    2016-02-01

    The warmest water reaching the east and west coast of Greenland is found between 200 and 600 m, in the warm Atlantic Water Layer (WL). Temperature changes within the WL have been highlighted as a possible cause of accelerated melting of tidewater glaciers and therefore are an important consideration for understanding global sea level rise. However, a limited number of winter observations of the WL have prohibited determining its seasonal variability. To address this, temperature data from Argo profiling floats, a range of sources within the World Ocean Database, and unprecedented coverage from marine-mammal borne sensors have been analyzed for the period 2002-2011. A significant seasonal range in temperature ( 1-2°C) is found in the warm layer, in contrast to most of the surrounding ocean. The magnitude of the seasonal cycle is thus comparable with the 1990s warming that was associated with an increased melt rate in a marine terminating glacier of West Greenland. The phase of the seasonal cycle exhibits considerable spatial variability; with high-resolution ocean model trajectory analysis suggesting it is determined by the time taken for waters to be advected from the subduction site in the Irminger Basin. For western Greenland, the annual temperature maximum occurs near or after the turn of the calendar year. This is significant because a recent study suggested that it is in the non-summer months when fjord-shelf exchanges allow the WL to most strongly influence glacier melt rate. However this is also the time of the year when the WL is least well observed. It is therefore clear that year-round subsurface temperature measurements are still required for a complete description of the WL seasonality, and in particular to ensure that the ice-melting potential of the WL is not underestimated.

  17. Effects of Serum Albumin, Calcium Levels, Cancer Stage and Performance Status on Weight Loss in Parathyroid Hormone-Related Peptide Positive or Negative Patients with Cancer

    Directory of Open Access Journals (Sweden)

    Ji-Yeon Lee

    2018-03-01

    Full Text Available BackgroundA recent animal study showed that parathyroid hormone-related peptide (PTHrP is associated with cancer cachexia by promoting adipose tissue browning, and we previously demonstrated that PTHrP predicts weight loss (WL in patients with cancer. In this study, we investigated whether prediction of WL by PTHrP is influenced by clinical factors such as serum albumin, corrected calcium levels, cancer stage, and performance status (PS.MethodsA cohort of 219 patients with cancer whose PTHrP level was measured was enrolled and followed for body weight (BW changes. Subjects were divided into two groups by serum albumin (cutoff value, 3.7 g/dL, corrected calcium (cutoff value, 10.5 mg/dL, cancer stage (stage 1 to 3 or 4, or PS (Eastern Cooperative Oncology Group 0 to 1 or 2 to 4, respectively. Clinically significant WL was defined as either percent of BW change (% BW <−5% or % BW <−2% plus body mass index (BMI <20 kg/m2.ResultsAfter a median follow-up of 327 days, 74 patients (33.8% experienced clinically significant WL. A positive PTHrP level was associated with a 2-fold increased risk of WL after adjusting for age, baseline BMI, serum albumin, corrected calcium level, cancer stage, and PS. The effect of PTHrP on WL remained significant in patients with low serum albumin, stage 4 cancer, and good PS. Regardless of calcium level, the effect of PTHrP on WL was maintained, although there was an additive effect of higher calcium and PTHrP levels.ConclusionEarly recognition of patients with advanced cancer who are PTHrP positive with hypercalcemia or hypoalbuminemia is needed for their clinical management.

  18. Effects of canal enlargement and irrigation needle depth on the cleaning of the root canal system at 3 mm from the apex

    Directory of Open Access Journals (Sweden)

    Ho-Jin Moon

    2012-02-01

    Full Text Available Objectives The aim of this study was to test the hypothesis, that the effectiveness of irrigation in removing smear layer in the apical third of root canal system is dependent on the depth of placement of the irrigation needle into the root canal and the enlargement size of the canal. Materials and Methods Eighty sound human lower incisors were divided into eight groups according to the enlargement size (#25, #30, #35 and #40 and the needle penetration depth (3 mm from working length, WL-3 mm and 9 mm from working length, WL-9 mm. Each canal was enlarged to working length with Profile.06 Rotary Ni-Ti files and irrigated with 5.25% NaOCl. Then, each canal received a final irrigation with 3 mL of 3% EDTA for 4 min, followed by 5 mL of 5.25% NaOCl at different level (WL-3 mm and WL-9 mm from working length. Each specimen was prepared for the scanning electron microscope (SEM. Photographs of the 3mm area from the apical constriction of each canal with a magnification of ×250, ×500, ×1,000, ×2,500 were taken for the final evaluation. Results Removal of smear layer in WL-3 mm group showed a significantly different effect when the canal was enlarged to larger than #30. There was a significant difference in removing apical smear layer between the needle penetration depth of WL-3 mm and WL-9 mm. Conclusions Removal of smear layer from the apical portion of root canals was effectively accomplished with apical instrumentation to #35/40 06 taper file and 3 mm needle penetration from the working length.

  19. Margins Associated with Loss of Assured Safety for Systems with Multiple Time-Dependent Failure Modes.

    Energy Technology Data Exchange (ETDEWEB)

    Helton, Jon C. [Arizona State Univ., Tempe, AZ (United States); Brooks, Dusty Marie [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sallaberry, Cedric Jean-Marie. [Engineering Mechanics Corp. of Columbus, OH (United States)

    2018-02-01

    Representations for margins associated with loss of assured safety (LOAS) for weak link (WL)/strong link (SL) systems involving multiple time-dependent failure modes are developed. The following topics are described: (i) defining properties for WLs and SLs, (ii) background on cumulative distribution functions (CDFs) for link failure time, link property value at link failure, and time at which LOAS occurs, (iii) CDFs for failure time margins defined by (time at which SL system fails) – (time at which WL system fails), (iv) CDFs for SL system property values at LOAS, (v) CDFs for WL/SL property value margins defined by (property value at which SL system fails) – (property value at which WL system fails), and (vi) CDFs for SL property value margins defined by (property value of failing SL at time of SL system failure) – (property value of this SL at time of WL system failure). Included in this presentation is a demonstration of a verification strategy based on defining and approximating the indicated margin results with (i) procedures based on formal integral representations and associated quadrature approximations and (ii) procedures based on algorithms for sampling-based approximations.

  20. Temporal trends in N2O flux dynamics in a Danish wetland – effects of plant-mediated gas transport of N2O and O2 following changes in water level and soil mineral-N availability

    DEFF Research Database (Denmark)

    Jørgensen, Christian Juncher; Struwe, Sten; Elberling, Bo

    2012-01-01

    in subsurface N2O and O2 concentrations, water level (WL), light intensity as well as mineral-N availability. Weekly concentration profiles showed that seasonal variations in N2O concentrations were directly linked to the position of the WL and O2 availability at the capillary fringe above the WL. N2O flux....... Complex interactions between seasonal changes in O2 and mineral-N availability following near-surface WL fluctuations in combination with plant-mediated gas transport by P. arundinacea controlled the subsurface N2O concentrations and gas transport mechanisms responsible for N2O fluxes across the soil......–atmosphere interface. Results demonstrate the necessity for addressing this high temporal variability and potential plant transport of N2O in future studies of net N2O exchange across the soil–atmosphere interface....

  1. Joint multifractal analysis based on wavelet leaders

    Science.gov (United States)

    Jiang, Zhi-Qiang; Yang, Yan-Hong; Wang, Gang-Jin; Zhou, Wei-Xing

    2017-12-01

    Mutually interacting components form complex systems and these components usually have long-range cross-correlated outputs. Using wavelet leaders, we propose a method for characterizing the joint multifractal nature of these long-range cross correlations; we call this method joint multifractal analysis based on wavelet leaders (MF-X-WL). We test the validity of the MF-X-WL method by performing extensive numerical experiments on dual binomial measures with multifractal cross correlations and bivariate fractional Brownian motions (bFBMs) with monofractal cross correlations. Both experiments indicate that MF-X-WL is capable of detecting cross correlations in synthetic data with acceptable estimating errors. We also apply the MF-X-WL method to pairs of series from financial markets (returns and volatilities) and online worlds (online numbers of different genders and different societies) and determine intriguing joint multifractal behavior.

  2. Recent e+e- results from DORIS

    International Nuclear Information System (INIS)

    Weber, G.

    1978-07-01

    This paper contains: some new results of the heavy lepton tau, evidence for the F- and F*-Mesons, observation of the Upsilon (9.46) Resonance, jets in hadron production in e + e - annihilation and status of PETRA. (WL) 891 WL [de

  3. Collapse Mechanisms Of Masonry Structures

    International Nuclear Information System (INIS)

    Zuccaro, G.; Rauci, M.

    2008-01-01

    The paper outlines a possible approach to typology recognition, safety check analyses and/or damage measuring taking advantage by a multimedia tool (MEDEA), tracing a guided procedure useful for seismic safety check evaluation and post event macroseismic assessment. A list of the possible collapse mechanisms observed in the post event surveys on masonry structures and a complete abacus of the damages are provided in MEDEA. In this tool a possible combination between a set of damage typologies and each collapse mechanism is supplied in order to improve the homogeneity of the damages interpretation. On the other hand recent researches of one of the author have selected a number of possible typological vulnerability factors of masonry buildings, these are listed in the paper and combined with potential collapse mechanisms to be activated under seismic excitation. The procedure takes place from simple structural behavior models, derived from the Umbria-Marche earthquake observations, and tested after the San Giuliano di Puglia event; it provides the basis either for safety check analyses of the existing buildings or for post-event structural safety assessment and economic damage evaluation. In the paper taking advantage of MEDEA mechanisms analysis, mainly developed for the post event safety check surveyors training, a simple logic path is traced in order to approach the evaluation of the masonry building safety check. The procedure starts from the identification of the typological vulnerability factors to derive the potential collapse mechanisms and their collapse multipliers and finally addresses the simplest and cheapest strengthening techniques to reduce the original vulnerability. The procedure has been introduced in the Guide Lines of the Regione Campania for the professionals in charge of the safety check analyses and the buildings strengthening in application of the national mitigation campaign introduced by the Ordinance of the Central Government n. 3362

  4. External modes in quantum dot light emitting diode with filtered optical feedback

    International Nuclear Information System (INIS)

    Al Husseini, Hussein B.; Al Naimee, Kais A.; Al-Khursan, Amin H.; Khedir, Ali. H.

    2016-01-01

    This research reports a theoretical investigation on the role of filtered optical feedback (FOF) in the quantum dot light emitting diode (QD-LED). The underlying dynamics is affected by a sidle node, which returns to an elliptical shape when the wetting layer (WL) is neglected. Both filter width and time delay change the appearance of different dynamics (chaotic and mixed mode oscillations, MMOs). The results agree with the experimental observations. Here, the fixed point analysis for QDs was done for the first time. For QD-LED with FOF, the system transits from the coherence collapse case in conventional optical feedback to a coherent case with a filtered mode in FOF. It was found that the WL washes out the modes which is an unexpected result. This may attributed to the longer capture time of WL compared with that between QD states. Thus, WL reduces the chaotic behavior.

  5. A survey of the concentration of radon and its daughters in air of the dugouts in three cities of Changsha, Hengyang and Zhuzhou

    International Nuclear Information System (INIS)

    Liu Hanqin; Xian Renyi; Zeng Xinyuan

    1986-01-01

    The concentrations of radon and its daughters in air of the dugouts was reported. This survey was made in three cities of Changsha, Hengyang and Zhuzhou. In dugouts which are used for cultivation of mushrooms (category I) or which have been reconstructed as hotels and the places for recreation (category II), the average concentration of radon and its daughter were found to be 0.451 Bq/l (12.2 pCi/l) and 0.872 μJ/m 3 (0.0419 WL) in Changsha, 0.710 Bq/l (19.2 pCi/l) and 1.47 μJ/m 3 (0.0709 WL) in Hengyang and 0.236 Bq/l (6.39 pCi/l) and 0.418 μJ/m 3 (0.0201 WL) in Zhuzhou, respectively. However, in those dugouts which have been reconstructed as the places for recreation the averange concentration of radon and its daughters were obtained to 0.566 Bq/l (15.3 pCi/l) and 0.940 μJ/m 3 (0.0452 WL) in Changsha, 1.10 Bq/l (29.8 pCi/l) and 2.83 μJ/m 3 (0.136 WL) in Hengyang and 0.511 Bq/l (13.8 pCi/l) and 0.982 μJ/m 3 (0.0472 WL) in Zhuzhou. For γ-rays, the range of exposure rate was 6-22 μR/h with a mean of 12 μR/h. The effective dose equivalent for persons working in these dugouts was estimated and some measures for radiation protection were suggested

  6. Before-after, control-impact analysis of evidence for the impacts of water level on Walleye, Northern Pike and Yellow Perch in lakes of the Rainy-Namakan complex (MN, USA and ON, CA.

    Directory of Open Access Journals (Sweden)

    James H Larson

    Full Text Available Water level (WL fluctuations in lakes influence many aspects of ecosystem processes. Concern about the potential impact of WL fluctuations on fisheries was one of the factors that motivated the decision in 2000 to alter the management of WL in the Rainy-Namakan reservoir complex (on the border between the U.S. state of Minnesota and the Canadian province of Ontario. We used a Before-After, Control-Impact (BACI framework to identify potential impacts of the change in WL management to Walleye, Northern Pike and Yellow Perch catch per unit effort (CPUE. The CPUE of these species from 1990-1999 and from 2005-2014 were compared in four impact lakes (Lake Kabetogama, Namakan Lake, Rainy Lake and Sand Point Lake and two control lakes (Lake of the Woods and Lake Vermilion using a simple Bayesian model. Changes in fish CPUE in the impact lakes were often similar to changes that occurred in at least one control lake. The only change that was not similar to changes in control lakes was an increase of Yellow Perch in Lake Kabetogama. The two control lakes often differed substantially from each other, such that if only one had been available our conclusions about the role of WL management on fisheries would be very different. In general, identifying cause-and-effect relationships in observational field data is very difficult, and the BACI analysis used here does not specify a causative mechanism, so co-occurring environmental and management changes may obscure the effect of WL management.

  7. Perturbation calculations with Wilson loop

    International Nuclear Information System (INIS)

    Peixoto Junior, L.B.

    1984-01-01

    We present perturbative calculations with the Wilson loop (WL). The dimensional regularization method is used with a special attention concerning to the problem of divergences in the WL expansion in second and fourth orders, in three and four dimensions. We show that the residue in the pole, in 4d, of the fourth order graphs contribution sum is important for the charge renormalization. We compute up to second order the exact expression of the WL, in three-dimensional gauge theories with topological mass as well as its assimptotic behaviour for small and large distances. the author [pt

  8. Electrical versus optical pumping of quantum dot amplifiers

    DEFF Research Database (Denmark)

    Berg, Tommy Winther; Bischoff, Svend; Mørk, Jesper

    2001-01-01

    The influence of the pumping mechanism for the dynamical properties of quantum dot amplifiers is investigated for 10, 40 and 160 GHz signals. A fast response is predicted in the case of optical pumping in the wetting layer (WL). The combination of fast relaxation and capture times and the presence...... of a reservoir of carriers in the WL opens up for the possibility of ultrafast gain recovery in QD devices. The strength of optical contra electrical pumping is that it reduces the bottleneck effect of a slow WL. Optical pumping thus allows significant improvement of the dynamical properties of QD devices....

  9. Quantitative Light-induced Fluorescence-Digital as an oral hygiene evaluation tool to assess plaque accumulation and enamel demineralization in orthodontics.

    Science.gov (United States)

    Miller, Cara C; Burnside, Girvan; Higham, Susan M; Flannigan, Norah L

    2016-11-01

      To assess the use of Quantitative Light-induced Fluorescence-Digital as an oral hygiene evaluation tool during orthodontic treatment.   In this prospective, randomized clinical trial, 33 patients undergoing fixed orthodontic appliance treatment were randomly allocated to receive oral hygiene reinforcement at four consecutive appointments using either white light (WL) or Quantitative Light-induced Fluorescence-Digital (QLF) images, taken with a device, as visual aids. Oral hygiene was recorded assessing the QLF images for demineralization, by fluorescence loss (ΔF), and plaque coverage (ΔR30). A debriefing questionnaire ascertained patient perspectives.   There were no significant differences in demineralization (P  =  .56) or plaque accumulation (P  =  .82) between the WL and QLF groups from T0 to T4. There was no significant reduction in demineralization, ΔF, in the WL, or the QLF group from T0-T4 (P > .05); however, there was a significant reduction in ΔR30 plaque scores (P orthodontics. Oral hygiene reinforcement at consecutive appointments using WL or QLF images as visual aids is effective in reducing plaque coverage. In terms of clinical benefits, QLF and WL images are of similar effectiveness; however, patients preferred the QLF images.

  10. Effects of reservoirs water level variations on fish recruitment

    Directory of Open Access Journals (Sweden)

    Fabíula T. de Lima

    2017-10-01

    Full Text Available ABSTRACT The construction of hydroelectric power plants has many social and environmental impacts. Among them, the impacts on fish communities, which habitats are drastically modified by dams, with consequences across the ecosystem. This study aimed to assess the influence of water level (WL variations in the reservoirs of the Itá and Machadinho hydroelectric plants on the recruitment of fish species from the upper Uruguay River in southern Brazil. The data analyzed resulted from the WL variation produced exclusively by the hydroelectric plants generation and were collected between the years 2001 and 2012. The results showed significant correlations between the abundance of juvenile fish and the hydrological parameters only for some reproductive guilds. The species that spawn in nests showed, in general, a clear preference for the stability in the WL of the reservoirs, while the species that spawn in macrophytes or that release demersal eggs showed no significant correlation between the abundance of juvenile fish and hydrological parameters. A divergence of results between the two reservoirs was observed between the species that release semi-dense eggs; a positive correlation with a more stable WL was only observed in the Machadinho reservoir. This result can be driven by a wider range of WL variation in Machadinho reservoir.

  11. Examination of tumor diameter measurement precision by RECIST

    International Nuclear Information System (INIS)

    Goto, Masami; Ino, Kenji; Akahane, Masaaki

    2007-01-01

    Image evaluation with Response Evaluation Criteria in Solid Tumors (RECIST) evaluates the change in a measurable lesion as determined by ruler or micrometer caliper. However, there is no definition of the conditions thought to influence the precision of measurement. We therefore examined the effects on measurement precision by changing image amplification, window width (WW), window level (WL), and time phase. Moreover, to determine response rate, one-dimensional evaluation with RECIST was compared with the two-dimensional evaluation of World Health Organization (WHO) for a hepatocellular carcinoma. The results of measuring the object lesion for measured value variation were as follows. Under image conditions of 1 time expansion/WW 150/WL 100 was (4.92±1.94)%. Under image conditions of 1 time expansion/WW 350/WL 75 was (4.42±1.70)%. Under image conditions of 4 times expansion/WW 150/WL 100 was (2.52±0.82)%. Under image conditions of 4 times expansion/WW 350/WL 75 was (2.83±1.10)%. When an image was enlarged to 4 times, precision doubled. There was no a difference in comparing RECIST to WHO in terms of response rate. Thus the best method was considered to be RECIST because of its convenience. (author)

  12. DEVELOPMENT OF A SIX SIGMA RATING SCALE FOR MEASURING THE QUALITY OF WORK LIFE OF TEACHING STAFF WORKING IN SAUDI UNIVERSITIES

    Directory of Open Access Journals (Sweden)

    Arun Vijay Subbarayalu

    2017-06-01

    Full Text Available Higher Education institutions in Saudi Arabia is currently performing several evaluations by both students and teaching staff as a measure to improve the quality by understanding the perception of its stakeholders. In order to retain the best and efficient work force to carry out the teaching roles in these universities, the Quality of Work Life (QoWL prevailing in these Educational institutions needs to be studied. Accordingly, this study was conducted among the teaching staff of the University of Dammam [UOD] to capture their experiences related to various aspects of the QoWL. The teaching staff opinion was captured through a pre-tested QoWL questionnaire and the data were analyzed through six sigma analytical tool using the Poisson distribution model. From the non-conformance level captured through the responses from the faculty/teaching staff about the various aspects of quality of work life prevailing in their respective colleges, the corresponding sigma rating for each component of QoWL was calculated. Subsequently, an innovative six point quality rating system was established for each sigma values. The overall opinion of teaching staff about the QoWL prevailing at UOD is rated as "Adaptable" signifying that there is room for further improvement and appropriate strategies need to be employed to improve it.

  13. Comparison of the chemical composition of dissolved organic matter in three lakes in Minnesota

    Science.gov (United States)

    Cao, Xiaoyan; Aiken, George R.; Butler, Kenna D.; Mao, Jingdong; Schmidt-Rohr, Klaus

    2018-01-01

    New information on the chemical composition of dissolved organic matter (DOM) in three lakes in Minnesota has been gained from spectral editing and two-dimensional nuclear magnetic resonance (NMR) methods, indicating the effects of lake hydrological settings on DOM composition. Williams Lake (WL), Shingobee Lake (SL), and Manganika Lake (ML) had different source inputs, and the lake water residence time (WRT) of WL was markedly longer than that of SL and ML. The hydrophobic organic acid (HPOA) and transphilic organic acid (TPIA) fractions combined comprised >50% of total DOM in these lakes, and contained carboxyl-rich alicyclic molecules (CRAM), aromatics, carbohydrates, and N-containing compounds. The previously understudied TPIA fractions contained fewer aromatics, more oxygen-rich CRAM, and more N-containing compounds compared to the corresponding HPOA. CRAM represented the predominant component in DOM from all lakes studied, and more so in WL than in SL and ML. Aromatics including lignin residues and phenols decreased in relative abundances from ML to SL and WL. Carbohydrates and N-containing compounds were minor components in both HPOA and TPIA and did not show large variations among the three lakes. The increased relative abundances of CRAM in DOM from ML, SL to WL suggested the selective preservation of CRAM with increased residence time.

  14. The Induction of Growth Inhibition and Apoptosis in HeLa and MCF-7 Cells by Teucrium sandrasicum, Having Effective Antioxidant Properties.

    Science.gov (United States)

    Tarhan, Leman; Nakipoğlu, Mahmure; Kavakcıoğlu, Berna; Tongul, Burcu; Nalbantsoy, Ayşe

    2016-03-01

    The hidromethanolic (Met/W), ethyl acetate (EA(EA/W)), and water (W(EA/W)) extracts from Teucrium sandrasicum leaves (L) and flowers (F) were investigated for antioxidant properties and antiproliferative effects on HeLa, MCF-7, and L929. The highest DPPH scavenging, metal chelating capacities, and total phenolic and flavonoid contents were observed in Met/WL. The highest hydroxyl scavenging and reducing power capacities were found in EA(EA/W)L. Met/WL, EA(EA/W)L and EA(EA/W)F inhibited cancer cell growths, while they did not show significant cytotoxicity on L929. While the reactive oxygen species (ROS) levels were generally close to controls in HeLa, they were induced in MCF-7 with the treatment of Met/WL, EA(EA/W)L, and EA(EA/W)F and acted as antioxidant for L929. The highest apoptosis inductions were observed in Met/WL-treated HeLa and EA(EA/W)L-treated MCF-7, which were supported with the changes in mitochondrial membrane potentials. The highest caspase-9 activities were found in Met/WL-treated HeLa and EA(EA/W)F-treated MCF-7. Caspase-3 activity was only induced in EA(EA/W)F-treated HeLa.

  15. Effects of mixed housing of birds from two genetic lines of laying hens on open field and manual restraint responses

    NARCIS (Netherlands)

    Uitdehaag, K.A.; Rodenburg, T.B.; Hierden, van Y.M.; Bolhuis, J.E.; Toscano, M.J.; Nicol, C.J.; Komen, J.

    2008-01-01

    Birds from Rhode Island Red (RIR) origin show a lower fear response and less feather pecking than birds from White Leghorn (WL) origin. This study investigated whether responses in fear eliciting tests were affected if RIR and WL birds were housed together. Experimental groups contained either birds

  16. Whey protein improves HDL/non-HDL ratio and body weight gain in rats subjected to the resistance exercise

    Directory of Open Access Journals (Sweden)

    Kely Raspante Teixeira

    2012-12-01

    Full Text Available The aim of this study was to evaluate the effects of resistance exercise, such as weight-lifting (WL on the biochemical parameters of lipid metabolism and cardiovascular disease risk in the rats fed casein (control or whey protein (WP diets. Thirty-two male Fisher rats were randomly assigned to sedentary or exercise-trained groups and were fed control or WP diets. The WL program consisted of inducing the animals to perform the sets of jumps with weights attached to the chest. After seven weeks, arteriovenous blood samples were collected for analysis. The WL or WP ingestion were able to improve the lipid profile, reducing the TC and non-HDL cholesterol concentrations, but only WP treatment significantly increased the serum HDL concentrations, thereby also affecting the TC/HDL and HDL/non-HDL ratios. However, WL plus WP was more effective in improving the HDL/non-HDL ratio than the exercise or WP ingestion alone and the body weight gain than exercise without WP ingestion.

  17. Determination of fibromyalgia syndrome after whiplash injuries: methodologic issues.

    Science.gov (United States)

    Robinson, James P; Theodore, Brian R; Wilson, Hilary D; Waldo, Peter G; Turk, Dennis C

    2011-06-01

    Problems in diagnosing fibromyalgia syndrome (FM) among motor vehicle collision (MVC) patients with whiplash (WL) include the following: the predominance of tender points (TPs) in the neck/shoulder girdle region; the 3-month duration of widespread pain criterion; and, the stability of diagnosis. The present study examined the prevalence of FM in a cohort (N = 326) patients with persistent neck pain 3 months after WL injury who were enrolled in a treatment program. Physical examinations were performed at baseline and at the end of treatment. Results indicated that WL patients had a greater proportion of neck/shoulder girdle TPs, relative to distal TPs. Compared with a matched cohort of treatment-seeking FM patients, WL patients indicated less distal TPs (mean = 7.3 TPs vs. mean = 5.6 TPs, P whiplash patients because of persistent localized tenderness after motor vehicle collisions. Copyright © 2011 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.

  18. Influence of cervical preflaring on apical file size determination.

    Science.gov (United States)

    Pecora, J D; Capelli, A; Guerisoli, D M Z; Spanó, J C E; Estrela, C

    2005-07-01

    To investigate the influence of cervical preflaring with different instruments (Gates-Glidden drills, Quantec Flare series instruments and LA Axxess burs) on the first file that binds at working length (WL) in maxillary central incisors. Forty human maxillary central incisors with complete root formation were used. After standard access cavities, a size 06 K-file was inserted into each canal until the apical foramen was reached. The WL was set 1 mm short of the apical foramen. Group 1 received the initial apical instrument without previous preflaring of the cervical and middle thirds of the root canal. Group 2 had the cervical and middle portion of the root canals enlarged with Gates-Glidden drills sizes 90, 110 and 130. Group 3 had the cervical and middle thirds of the root canals enlarged with nickel-titanium Quantec Flare series instruments. Titanium-nitrite treated, stainless steel LA Axxess burs were used for preflaring the cervical and middle portions of root canals from group 4. Each canal was sized using manual K-files, starting with size 08 files with passive movements until the WL was reached. File sizes were increased until a binding sensation was felt at the WL, and the instrument size was recorded for each tooth. The apical region was then observed under a stereoscopic magnifier, images were recorded digitally and the differences between root canal and maximum file diameters were evaluated for each sample. Significant differences were found between experimental groups regarding anatomical diameter at the WL and the first file to bind in the canal (P Flare instruments were ranked in an intermediary position, with no statistically significant differences between them (0.093 mm average). The instrument binding technique for determining anatomical diameter at WL is not precise. Preflaring of the cervical and middle thirds of the root canal improved anatomical diameter determination; the instrument used for preflaring played a major role in determining the

  19. Mixed housing of different genetic lines of laying hens negatively affects feather pecking and fear related behaviour

    NARCIS (Netherlands)

    Uitdehaag, K.A.; Rodenburg, T.B.; Bolhuis, J.E.; Decuypere, E.; Komen, J.

    2009-01-01

    Adult laying hens from Rhode Island Red (RIR) origin both express lower levels of feather pecking and lower fear responses towards a novel object than laying hens from White Leghorn (WL) origin. The present study investigated whether mixed housing of RIR and WL laying hens would affect their

  20. Effect of Exclusive Breastfeeding Among Overweight and Obese Mothers on Infant Weight-for-Length Percentile at 1 Year.

    Science.gov (United States)

    Yeung, Hui; Leff, Michelle; Rhee, Kyung E

    Breastfeeding is associated with decreased risk of childhood obesity. However, there is a strong correlation between maternal weight status and childhood obesity, and it is unclear whether or not breastfeeding among overweight mothers could mitigate this risk. Our goal was to examine whether or not exclusive breastfeeding (compared to formula feeding) among overweight and obese mothers is associated with lower weight-for-length (W/L) percentile at 1 year. Data from the Infant Feeding Practices II study were used. Infants who were preterm or underweight at 1 year, and mothers who were underweight before pregnancy, were excluded from analysis. There was a significant interaction between exclusive breastfeeding for 4 months and maternal prepregnancy weight status (normal weight, overweight, obese) on infant W/L percentile at 1 year. Stratified linear mixed-effects growth modeling controlling for covariates was created to test the relationship between exclusive breastfeeding and infant W/L percentile within each maternal weight category. A total of 915 subjects met inclusion criteria. Normal weight and obese mothers who exclusively breastfed for 4 months had infants with a smaller rate of increase in W/L percentile during the first year compared with those who used formula. Infants of overweight and obese mothers who exclusively breastfed for 4 months had lower W/L percentile at 1 year than those who used formula. Exclusive breastfeeding for 4 months among normal weight and obese mothers resulted in less increase in W/L percentiles in the first year. Obese mothers often have a difficult time initiating and maintaining breastfeeding. Concerted efforts are needed to support this population with breastfeeding.

  1. Diagnostic and Prognostic Value of the Combination of Two Measures of Verbal Memory in Mild Cognitive Impairment due to Alzheimer's Disease.

    Science.gov (United States)

    Sala, Isabel; Illán-Gala, Ignacio; Alcolea, Daniel; Sánchez-Saudinós, Ma Belén; Salgado, Sergio Andrés; Morenas-Rodríguez, Estrella; Subirana, Andrea; Videla, Laura; Clarimón, Jordi; Carmona-Iragui, María; Ribosa-Nogué, Roser; Blesa, Rafael; Fortea, Juan; Lleó, Alberto

    2017-01-01

    Episodic memory impairment is the core feature of typical Alzheimer's disease. To evaluate the performance of two commonly used verbal memory tests to detect mild cognitive impairment due to Alzheimer's disease (MCI-AD) and to predict progression to Alzheimer's disease dementia (AD-d). Prospective study of MCI patients in a tertiary memory disorder unit. Patients underwent an extensive neuropsychological battery including two tests of declarative verbal memory: The Free and Cued Selective Reminding Test (FCSRT) and the word list learning task from the Consortium to Establish a Registry for Alzheimer's disease (CERAD-WL). Cerebrospinal fluid (CSF) was obtained from all patients and MCI-AD was defined by means of the t-Tau/Aβ1-42 ratio. Logistic regression analyses tested whether the combination of FCSRT and CERAD-WL measures significantly improved the prediction of MCI-AD. Progression to AD-d was analyzed in a Cox regression model. A total of 202 MCI patients with a mean follow-up of 34.2±24.2 months were included and 98 (48.5%) met the criteria for MCI-AD. The combination of FCSRT and CERAD-WL measures improved MCI-AD classification accuracy based on CSF biomarkers. Both tests yielded similar global predictive values (59.9-65.3% and 59.4-62.8% for FCSRT and CERAD-WL, respectively). MCI-AD patients with deficits in both FCSRT and CERAD-WL had a faster progression to AD-d than patients with deficits in only one test. The combination of FCSRT and CERAD-WL improves the classification of MCI-AD and defines different prognostic profiles. These findings have important implications for clinical practice and the design of clinical trials.

  2. Impact of a primordial magnetic field on cosmic microwave background B modes with weak lensing

    Science.gov (United States)

    Yamazaki, Dai G.

    2018-05-01

    We discuss the manner in which the primordial magnetic field (PMF) suppresses the cosmic microwave background (CMB) B mode due to the weak-lensing (WL) effect. The WL effect depends on the lensing potential (LP) caused by matter perturbations, the distribution of which at cosmological scales is given by the matter power spectrum (MPS). Therefore, the WL effect on the CMB B mode is affected by the MPS. Considering the effect of the ensemble average energy density of the PMF, which we call "the background PMF," on the MPS, the amplitude of MPS is suppressed in the wave number range of k >0.01 h Mpc-1 . The MPS affects the LP and the WL effect in the CMB B mode; however, the PMF can damp this effect. Previous studies of the CMB B mode with the PMF have only considered the vector and tensor modes. These modes boost the CMB B mode in the multipole range of ℓ>1000 , whereas the background PMF damps the CMB B mode owing to the WL effect in the entire multipole range. The matter density in the Universe controls the WL effect. Therefore, when we constrain the PMF and the matter density parameters from cosmological observational data sets, including the CMB B mode, we expect degeneracy between these parameters. The CMB B mode also provides important information on the background gravitational waves, inflation theory, matter density fluctuations, and the structure formations at the cosmological scale through the cosmological parameter search. If we study these topics and correctly constrain the cosmological parameters from cosmological observations, including the CMB B mode, we need to correctly consider the background PMF.

  3. A pilot study on the functional performance and acceptability of an innovative female condom (Wondaleaf®) in Malaysia

    Science.gov (United States)

    Wong, Ee-Lynn; Tnay, Jessie Koh-Sing

    2018-01-01

    Background Female condom (FC) has been available for over 30 years, but it still lacks wide acceptability. To overcome misdirection and invagination occurring in FC and to provide a wider area of protection, Wondaleaf® (WL), a new-generation adhesive FC, was recently invented. This pioneering study sought to assess the acceptability and functional performance of WL among Malaysian women. Methods A mixed method survey was conducted in three cities of Malaysia, recruiting sexually active heterosexual women, aged 18–50, by snowball sampling method. Participants were provided with WL and initially surveyed to rate its performance in five coital usages over 2 months. After that, the participants underwent a second survey to rate their satisfaction and acceptability toward WL. Descriptive statistics on clinical failure rates were tabulated with correlational analysis performed to identify major variables contributing to WL’s functional performance and acceptability. Results Out of the 51 enrolled participants, 31 women completed the required surveys. WL’s total clinical failure rate was 2.60% (out of 155 condom uses) with above-average ratings of functional performance. The ease of use significantly correlated with ratings of no slippage and no misdirection. The confidence in WL’s safety features significantly correlated with a sense of empowerment and protection. Conclusion WL has a relatively low risk of clinical failures and an overall favorable acceptability among Malaysian women. However, this study also showed that its future usage largely depends on partner acceptability. It may have the potential of complementing the existing barrier toward contraceptive use. Further studies are needed to understand the global acceptability of WL. PMID:29440937

  4. A TWO-RIBBON WHITE-LIGHT FLARE ASSOCIATED WITH A FAILED SOLAR ERUPTION OBSERVED BY ONSET, SDO, AND IRIS

    International Nuclear Information System (INIS)

    Cheng, X.; Hao, Q.; Ding, M. D.; Chen, P. F.; Fang, C.; Liu, K.; Liu, Y. D.

    2015-01-01

    Two-ribbon brightenings are one of the most remarkable characteristics of an eruptive solar flare and are often used to predict the occurrence of coronal mass ejections (CMEs). Nevertheless, it was recently called into question whether all two-ribbon flares are eruptive. In this paper, we investigate a two-ribbon-like white-light (WL) flare that is associated with a failed magnetic flux rope (MFR) eruption on 2015 January 13, which has no accompanying CME in the WL coronagraph. Observations by the Optical and Near-infrared Solar Eruption Tracer and the Solar Dynamics Observatory reveal that with the increase of the flare emission and the acceleration of the unsuccessfully erupting MFR, two isolated kernels appear at the WL 3600 Å passband and quickly develop into two elongated ribbon-like structures. The evolution of the WL continuum enhancement is completely coincident in time with the variation of Fermi hard X-ray 26–50 keV flux. An increase of continuum emission is also clearly visible at the whole FUV and NUV passbands observed by the Interface Region Imaging Spectrograph. Moreover, in one WL kernel, the Si iv, C ii, and Mg ii h/k lines display significant enhancement and non-thermal broadening. However, their Doppler velocity pattern is location-dependent. At the strongly bright pixels, these lines exhibit a blueshift, while at moderately bright ones, the lines are generally redshifted. These results show that the failed MFR eruption is also able to produce a two-ribbon flare and high-energy electrons that heat the lower atmosphere, causing the enhancement of the WL and FUV/NUV continuum emissions and chromospheric evaporation

  5. Dephasing rates for weak localization and universal conductance fluctuations in two dimensional Si:P and Ge:P δ-layers.

    Science.gov (United States)

    Shamim, Saquib; Mahapatra, S; Scappucci, G; Klesse, W M; Simmons, M Y; Ghosh, Arindam

    2017-05-04

    We report quantum transport measurements on two dimensional (2D) Si:P and Ge:P δ-layers and compare the inelastic scattering rates relevant for weak localization (WL) and universal conductance fluctuations (UCF) for devices of various doping densities (0.3-2.5 × 10 18 m -2 ) at low temperatures (0.3-4.2 K). The phase breaking rate extracted experimentally from measurements of WL correction to conductivity and UCF agree well with each other within the entire temperature range. This establishes that WL and UCF, being the outcome of quantum interference phenomena, are governed by the same dephasing rate.

  6. Present practices of the Department of National Health and Welfare for the area monitoring of radon and daughter products

    International Nuclear Information System (INIS)

    Taniguchi, H.

    1977-01-01

    The present practices of the Radiation Protection Bureau for the measurement of radon and daughter products have been briefly described. For radon gas, the Lucas chamber method is in use. Short-lived radon daughter products are determined by the modified Kusnetz method. These field methods are supported by radioanalytical procedures carried out at the environmental radioactivity laboratory. Some recent studies using these methods have been briefly summarized. Concentrations of daughter products up to 29 WL were found in a columbium mine and 63 WL in a tin mine under development. The level of radon daughters in some homes in a uranium mining community ranged up to 2 WL

  7. Effects of ultrasonic pretreatments on quality, energy consumption and sterilization of barley grass in freeze drying.

    Science.gov (United States)

    Cao, Xiaohuang; Zhang, Min; Mujumdar, Arun S; Zhong, Qifeng; Wang, Zhushang

    2018-01-01

    Barley grass is a plant resource for rehabilitation therapy. Its processing requires retaining nutrition well for rehabilitation cure of consumers. To meet the aim as well as low energy consumption and microbiological safety of products, ultrasonic treatments (UT) were applied to bathing materials at different power levels (10, 30, 45, 60W/L) for 10mins. After treatments, the bathed barley grass (100g) was freeze-dried under vacuum -0.09MPa with fixed power of 2W/g. Parameters of color, microbial colony, energy consumption, glass transition temperature, moisture content, water activity, taste substances, contents of flavonoid and chlorophyll were determined after drying. In contrast with no treatment case, UT (45W/L) decreased drying time by 14% and decreased energy consumption by 19%; UT (60W/L) decreased total microbial colonies by 33%. Also, UT (30W/L) yielded contents of flavonoid (9.2/kg) and chlorophyll (10.5g/kg) of dried sample; UT power (10W/L) yielded the highest L ∗ (51.5) and the lowest a ∗ (-9.3) value. Simultaneously, UT leads to a higher glass transition temperature (Tg), lower water activity and produces less sourness and bitterness of dried products. Ultra-sonication is an alternative to improve quality, flavor and energy consumption of barley grass in freeze drying. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Perceptions of Barriers to Effective Obesity Care: Results from the National ACTION Study.

    Science.gov (United States)

    Kaplan, Lee M; Golden, Angela; Jinnett, Kimberly; Kolotkin, Ronette L; Kyle, Theodore K; Look, Michelle; Nadglowski, Joseph; O'Neil, Patrick M; Parry, Thomas; Tomaszewski, Kenneth J; Stevenin, Boris; Lilleøre, Søren Kruse; Dhurandhar, Nikhil V

    2018-01-01

    ACTION (Awareness, Care, and Treatment in Obesity maNagement) examined obesity-related perceptions, attitudes, and behaviors among people with obesity (PwO), health care providers (HCPs), and employer representatives (ERs). A total of 3,008 adult PwO (BMI ≥ 30 by self-reported height and weight), 606 HCPs, and 153 ERs completed surveys in a cross-sectional design. Despite several weight loss (WL) attempts, only 23% of PwO reported 10% WL during the previous 3 years. Many PwO (65%) recognized obesity as a disease, but only 54% worried their weight may affect future health. Most PwO (82%) felt "completely" responsible for WL; 72% of HCPs felt responsible for contributing to WL efforts; few ERs (18%) felt even partially responsible. Only 50% of PwO saw themselves as "obese," and 55% reported receiving a formal diagnosis of obesity. Despite HCPs' reported comfort with weight-related conversations, time constraints deprioritized these efforts. Only 24% of PwO had a scheduled follow-up to initial weight-related conversations. Few PwO (17%) perceived employer-sponsored wellness offerings as helpful in supporting WL. Although generally perceived as a disease, obesity is not commonly treated as such. Divergence in perceptions and attitudes potentially hinders better management. This study highlights inconsistent understanding of the impact of obesity and need for both self-directed and medical management. © 2017 The Obesity Society.

  9. The influence of determining the working length with an apex locator on the amount of apically extruded debris following instrumentation with ProTaper Next and HyFlex CM

    Directory of Open Access Journals (Sweden)

    Ersan Çiçek

    2016-01-01

    Full Text Available Aim: The amount of apically extruded debris caused by new nickel-titanium rotary systems after determination of the working length (WL with an apex locator has not been investigated. To compare the amount of apically extruded debris with ProTaper Next (PTN and HyFlex CM systems after determination of WL with/without an apex locator. Materials and Methods: Forty-eight extracted mandibular incisor teeth divided into four groups were used in this study. In Groups 1 and 2, a 10 K-file was progressed until it was just visible at the major apical foramen and WL was recorded as 1 mm short. In Groups 3 and 4, the WL was determined with the Root ZX (sensitivity of 0.1 using a 10 K-file. During the instrumentation, the PTN was used to X2 in groups 1 and 3, and the HyFlex CM was used to 25/.06 in groups 2 and 4. Distilled water was used as an irrigant. Debris was collected in tubes then stored in an incubator at 68°C for 5 days to evaporate the distilled water. The Eppendorf tubes, including the extruded debris, were weighed to obtain final weights. The amount of extruded debris was calculated by subtracting the weight of the empty tube from the weight of the dry tube. Data were analyzed by Kruskal–Wallis and Mann–Whitney U-test. Results: Less apically extruded debris was obtained in Group 3, with a significant difference compared to Group 1 and Group 2 (P < 0.05. Conclusions: The usage of apex locator to determine the WL decreased the amount of apically extruded debris. In addition, PTN caused less apical debris extrusion after determination WL with/without apex locator.

  10. New genetic signatures associated with cancer cachexia as defined by low skeletal muscle index and weight loss.

    Science.gov (United States)

    Johns, Neil; Stretch, Cynthia; Tan, Benjamin H L; Solheim, Tora S; Sørhaug, Sveinung; Stephens, Nathan A; Gioulbasanis, Ioannis; Skipworth, Richard J E; Deans, D A Christopher; Vigano, Antonio; Ross, James A; Bathe, Oliver F; Tremblay, Michel L; Kaasa, Stein; Strasser, Florian; Gagnon, Bruno; Baracos, Vickie E; Damaraju, Sambasivarao; Fearon, Kenneth C H

    2017-02-01

    Cachexia affects the majority with advanced cancer. Based on current demographic and clinical factors, it is not possible to predict who will develop cachexia or not. Such variation may, in part, be due to genotype. It has recently been proposed to extend the diagnostic criteria for cachexia to include a direct measure of low skeletal muscle index (LSMI) in addition to weight loss (WL). We aimed to explore our panel of candidate single nucleotide polymorphism (SNPs) for association with WL +/- computerized tomography-defined LSMI. We also explored whether the transcription in muscle of identified genes was altered according to such cachexia phenotype METHODS: A retrospective cohort study design was used. Analysis explored associations of candidate SNPs with WL (n = 1276) and WL + LSMI (n = 943). Human muscle transcriptome (n = 134) was analysed using an Agilent platform. Single nucleotide polymorphisms in the following genes showed association with WL alone: GCKR, LEPR, SELP, ACVR2B, TLR4, FOXO3, IGF1, CPN1, APOE, FOXO1, and GHRL. SNPs in LEPR, ACVR2B, TNF, and ACE were associated with concurrent WL + LSMI. There was concordance between muscle-specific expression for ACVR2B, FOXO1 and 3, LEPR, GCKR, and TLR4 genes and LSMI and/or WL (P < 0.05). The rs1799964 in the TNF gene and rs4291 in the ACE gene are new associations when the definition of cachexia is based on a combination of WL and LSMI. These findings focus attention on pro-inflammatory cytokines and the renin-angiotensin system as biomarkers/mediators of muscle wasting in cachexia. © 2016 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of the Society on Sarcopenia, Cachexia and Wasting Disorders.

  11. Biology of two larval morphological phenotypes of Aedes aegypti in Abidjan, Côte d'Ivoire.

    Science.gov (United States)

    Guindo-Coulibaly, N; Diakite, N R; Adja, A M; Coulibaly, J T; Bassa, K F; Konan, Y L; N'Goran, K E

    2017-11-23

    Since 2008, several outbreaks of yellow fever and dengue occurred in Abidjan, the economic capital of Côte d'Ivoire. A better knowledge of the biology of Aedes aegypti populations, the main vector of yellow fever and dengue viruses, is necessary to tailor vector control strategies implemented in the city. This study was designed to determine some biological parameters, occurring during the life cycle of two morphological phenotypes of Ae. aegypti larvae. Mosquitoes were sampled in a suburb of Abidjan (Treichville) using the WHO layer-traps technique. Biological parameters were studied in laboratory under standard conditions of temperature (27°C ± 2°C) and relative humidity (80% ± 10%). Our results indicated that the mean eggs laid by females from 'brown larvae' (BL) (85.95, 95% confidence interval (CI 95%) 78.87-93.02) was higher than those from 'white larvae' (WL) (64.40%, CI 95% 55.27-73.54). The gonotrophic cycle was 3 and 4 days in females from BL and WL, respectively. The overall yield of breeding mosquitoes from BL (63.88%, CI 95% 62.61-65.14) was higher compared with those of mosquitoes from WL (59.73%, CI 95% 58.35-61.12). The sex ratio (male/female) was 0.95 and 1.68 in Ae. aegypti populations from BL and WL, respectively. Females from BL lived slightly longer than those from WL (t = -2.332; P = 0.021). This study shows that Ae. Aegypti populations from BL and WL present different biological parameters during their life cycle. This could have an implication on their ability to transmit human disease viruses such as dengue and yellow fever. Further molecular studies are needed to determine genetic divergence between these Ae. aegypti populations.

  12. USING COORDINATED OBSERVATIONS IN POLARIZED WHITE LIGHT AND FARADAY ROTATION TO PROBE THE SPATIAL POSITION AND MAGNETIC FIELD OF AN INTERPLANETARY SHEATH

    Energy Technology Data Exchange (ETDEWEB)

    Xiong, Ming; Feng, Xueshang; Liu, Ying D. [State Key Laboratory of Space Weather, Center for Space Science and Applied Research, Chinese Academy of Sciences, Beijing (China); Davies, Jackie A.; Harrison, Richard A. [Rutherford-Appleton Laboratory (RAL) Space, Harwell Oxford (United Kingdom); Owens, Mathew J.; Davis, Chris J., E-mail: mxiong@spacweather.ac.cn [Reading University, Reading (United Kingdom)

    2013-11-01

    Coronal mass ejections (CMEs) can be continuously tracked through a large portion of the inner heliosphere by direct imaging in visible and radio wavebands. White light (WL) signatures of solar wind transients, such as CMEs, result from Thomson scattering of sunlight by free electrons and therefore depend on both viewing geometry and electron density. The Faraday rotation (FR) of radio waves from extragalactic pulsars and quasars, which arises due to the presence of such solar wind features, depends on the line-of-sight magnetic field component B{sub ∥} and the electron density. To understand coordinated WL and FR observations of CMEs, we perform forward magnetohydrodynamic modeling of an Earth-directed shock and synthesize the signatures that would be remotely sensed at a number of widely distributed vantage points in the inner heliosphere. Removal of the background solar wind contribution reveals the shock-associated enhancements in WL and FR. While the efficiency of Thomson scattering depends on scattering angle, WL radiance I decreases with heliocentric distance r roughly according to the expression I∝r {sup –3}. The sheath region downstream of the Earth-directed shock is well viewed from the L4 and L5 Lagrangian points, demonstrating the benefits of these points in terms of space weather forecasting. The spatial position of the main scattering site r{sub sheath} and the mass of plasma at that position M{sub sheath} can be inferred from the polarization of the shock-associated enhancement in WL radiance. From the FR measurements, the local B{sub ∥sheath} at r{sub sheath} can then be estimated. Simultaneous observations in polarized WL and FR can not only be used to detect CMEs, but also to diagnose their plasma and magnetic field properties.

  13. Comparison of five-minute radon-daughter measurements with long-term radon and radon-daughter concentrations

    International Nuclear Information System (INIS)

    Young, J.A.; Jackson, P.O.; Thomas, V.W.

    1983-01-01

    Five-minute air filter radon daughter measurements were made in 84 buildings in Edgemont, South Dakota, in which annual average radon daughter concentrations have been determined from six 100-hour Radon Progeny Integrating Sampling Unit (RPISU) measurements. Averaging radon concentrations were also determined in 50 of these buildings using Terradex Track Etch detectors. The standard deviation of the difference between the (natural) logarithms of the RPISU annual averages and the logarithms of the air filter measurements (SD-ln) was found to be 0.52. This SD-ln is considerably smaller than the SD-ln of 0.71 between the RPISU annual averages and the air filter measurements reported by ALARA at Grand Junction, Colorado; presumably because a considerable number of air filter measurements in Edgemont were disregarded because of short turnover times or high wind speeds. Using the SD-ln of 0.52 it can be calculated that there would only be a 5% probability in Edgemont that the RPISU annual average would be greater than 0.015 WL if the five-minute measurement were equal to 0.010 WL. This indicates that the procedure used in Edgemont of clearing buildings from remedial action if the five-minute measurement were less than 0.010 WL was reasonable. There was about a 28% probability that the RPISU annual average would be less than 0.015 WL if the five-minute measurement were 0.033 WL, indicating that the procedure of performing an engineering assessment if the average of two five-minute measurements was greater than 0.033 WL was also reasonable. Comparison indicates that the average of two RPISU measurements taken six months apart would provide a dependable estimate of the annual average

  14. 78 FR 11459 - Implementation of the Fair Housing Act's Discriminatory Effects Standard

    Science.gov (United States)

    2013-02-15

    ...] may be premised on a theory of disparate impact.''); HUD v. Carlson, No. 08-91-0077-1, 1995 WL 365009... justified by business necessity.''); HUD v. Ross, No. 01-92-0466-18, 1994 WL 326437, at *5 (HUD ALJ July 7, 1994) (``Absent a showing of business necessity, facially neutral policies which have a discriminatory...

  15. Identification of a Novel Vasodilatory Octapeptide from the Skin Secretion of the African Hyperoliid Frog, Kassina senegalensis.

    Science.gov (United States)

    Du, Qiang; Wang, Hui; Ma, Chengbang; Wu, Yue; Xi, Xinping; Zhou, Mei; Chen, Tianbao; Shaw, Chris; Wang, Lei

    2017-07-19

    The defensive skin secretions of amphibians continue to be an excellent source of novel biologically-active peptides. Here we report the identification and pharmacological activity of a novel C-terminally amided myotropic octapeptide from the skin secretion of the African hyperoliid frog, Kassina senegalensis . The 8-amino acid peptide has the following primary structure: WMSLGWSL-amide and has a molecular mass of 978 Da. The primary structure and organisation of the biosynthetic precursor of WL-8 amide was successfully deduced from cloned skin secretion-derived cDNA. The open-reading frame encoded a single copy of WL-8, located at the C-terminus. Synthetic WL-8 amide was found to cause relaxation of rat tail artery smooth muscle with an EC 50 of 25.98 nM. This peptide is unique in terms of its primary structure and is unlike any other peptide previously isolated from an amphibian source which has been archived in the NCBI database. WL-8 amide thus represents the prototype of a novel family of myotropic peptide from amphibian defensive skin secretions.

  16. Virtual Monoenergetic Images From a Novel Dual-Layer Spectral Detector Computed Tomography Scanner in Portal Venous Phase: Adjusted Window Settings Depending on Assessment Focus Are Essential for Image Interpretation.

    Science.gov (United States)

    Hickethier, Tilman; Iuga, Andra-Iza; Lennartz, Simon; Hauger, Myriam; Byrtus, Jonathan; Luetkens, Julian A; Haneder, Stefan; Maintz, David; Doerner, Jonas

    We aimed to determine optimal window settings for conventional polyenergetic (PolyE) and virtual monoenergetic images (MonoE) derived from abdominal portal venous phase computed tomography (CT) examinations on a novel dual-layer spectral-detector CT (SDCT). From 50 patients, SDCT data sets MonoE at 40 kiloelectron volt as well as PolyE were reconstructed and best individual window width and level values manually were assessed separately for evaluation of abdominal arteries as well as for liver lesions. Via regression analysis, optimized individual values were mathematically calculated. Subjective image quality parameters, vessel, and liver lesion diameters were measured to determine influences of different W/L settings. Attenuation and contrast-to-noise values were significantly higher in MonoE compared with PolyE. Compared with standard settings, almost all adjusted W/L settings varied significantly and yielded higher subjective scoring. No differences were found between manually adjusted and mathematically calculated W/L settings. PolyE and MonoE from abdominal portal venous phase SDCT examinations require appropriate W/L settings depending on reconstruction technique and assessment focus.

  17. Heterogenous Oxygen Isotopic Composition of a Complex Wark-Lovering Rim and the Margin of a Refractory Inclusion from Leoville

    Science.gov (United States)

    Simon, J. I.; Matzel, J. E. P.; Simon, S. B.; Weber, P. K.; Grossman, L.; Ross, D. K.; Hutcheon, I. D.

    2014-01-01

    Wark-Lovering (WL) rims [1] surrounding many refractory inclusions represent marker events in the early evolution of the Solar System in which many inclusions were exposed to changes in pressure [2], temperature [3], and isotopic reservoirs [4-7]. The effects of these events can be complex, not only producing mineralogical variability of WL rims [2], but also leading to mineralogical [8-10] and isotopic [7, 11, 12] changes within inclusion interiors. Extreme oxygen isotopic heterogeneity measured in CAIs has been explained by mixing between distinct oxygen gas reservoirs in the nebula [13]. Some WL rims contain relatively simple mineral layering and/or are isotopically homogeneous [14, 15]. As part of a larger effort to document and understand the modifications observed in some CAIs, an inclusion (L6) with a complex WL rim from Leoville, a member of the reduced CV3 subgroup was studied. Initial study of the textures and mineral chemistry was presented by [16]. Here we present NanoSIMS oxygen isotopic measurements to complement these petrologic observations.

  18. Application of Peleg model to study mass transfer during osmotic dehydration of apple in sugar beet molasses

    Directory of Open Access Journals (Sweden)

    Mišljenović Nevena M.

    2011-01-01

    Full Text Available The applicability of Peleg equation was examined for the description of mass transfer during osmotic dehydration (OD of apple in sugar beet molasses. Mass transfer was investigated in terms of water loss (WL and solid gain (SG, during OD in 40-80% sugar beet molasses solutions, at 45, 55 and 65ºC. High regression coefficients obtained for Peleg constants (R2>0.975 indicate good fit to the experimental data. The Peleg rate constant varied from 0.144 to 0.785 (g/g i.s.w. and from 2.006 to 4.436 (g/g i.s.w. for WL and SG, respectively. The Peleg capacity constant varied from 1.142 to 1.553 (h g/g i.s.w. and from 8.254 to 11.930 (h g/g i.s.w. for WL and SG, respectively. The equilibrium WL∞ and SG∞ were estimated using the Peleg model. In addition, the activation energy (Ea for WL and SG was determined from the relationship between the Peleg rate constant and Arrhenius equation.

  19. Negative and positive magnetoresistance in bilayer graphene: Effects of weak localization and charge inhomogeneity

    International Nuclear Information System (INIS)

    Chen Yungfu; Bae, Myung-Ho; Chialvo, Cesar; Dirks, Travis; Bezryadin, Alexey; Mason, Nadya

    2011-01-01

    We report measurements of magnetoresistance in bilayer graphene as a function of gate voltage (carrier density) and temperature. We examine multiple contributions to the magnetoresistance, including those of weak localization (WL), universal conductance fluctuations (UCF), and inhomogeneous charge transport. A clear WL signal is evident at all measured gate voltages (in the hole doped regime) and temperature ranges (from 0.25 to 4.3 K), and the phase coherence length extracted from the WL data does not saturate at low temperatures. The WL data is fit to demonstrate that the electron-electron Nyquist scattering is the major source of phase decoherence. A decrease in UCF amplitude with increase in gate voltage and temperature is shown to be consistent with a corresponding decrease in the phase coherence length. In addition, a weak positive magnetoresistance at higher magnetic fields is observed, and attributed to inhomogeneous charge transport. -- Research highlights: → Weak localization theory describes low-field magnetoresistance in bilayer graphene. → Electron-electron Nyquist scattering limits phase coherence in bilayer graphene. → Positive magnetoresistance reveals charge inhomogeneity in bilayer graphene.

  20. Water Resources Improvement Study, Buttermilk Bay Channel, Bourne, Massachusetts; Small Navigation Project, Detailed Project Report, and Environmental Assessment.

    Science.gov (United States)

    1982-12-01

    samples are surface grabs and were found to be non- radioactive . Table 6 SEDIMENT SAHPLES - Hi’YSICAL CHARACTERISTICS Saiaple Depth Description G,,-2a...soiuices of polution ; ind d. That the discharge wall not occur in a component of the NotionlWl n cncRvrSse ri opnn faSaewl and scenic river system. nlWl n

  1. Systematic factors that affect ostrich egg incubation traits | Brand ...

    African Journals Online (AJOL)

    Data obtained from a pair-mated ostrich flock maintained at Oudtshoorn, South Africa, were used to estimate environmental and genetic parameters for egg weight (EWT), water loss of incubated eggs up to 21 days (WL21), water loss up to 35 days (WL35), pipping time (PT) and weight of day-old chicks (CWT). Between ...

  2. The habenula as a novel link between the homeostatic and hedonic pathways in cancer-associated weight loss: a pilot study.

    Science.gov (United States)

    Maldonado, Maria; Molfese, David L; Viswanath, Humsini; Curtis, Kaylah; Jones, Ashley; Hayes, Teresa G; Marcelli, Marco; Mediwala, Sanjay; Baldwin, Philip; Garcia, Jose M; Salas, Ramiro

    2018-03-25

    Little is known about the brain mechanisms underlying cancer-associated weight loss (C-WL) in humans despite this condition negatively affecting their quality of life and survival. We tested the hypothesis that patients with C-WL have abnormal connectivity in homeostatic and hedonic brain pathways together with altered brain activity during food reward. In 12 patients with cancer and 12 healthy controls, resting-state functional connectivity (RSFC, resting brain activity observed through changes in blood flow in the brain which creates a blood oxygen level-dependent signal that can be measured using functional magnetic resonance imaging) was used to compare three brain regions hypothesized to play a role in C-WL: the hypothalamus (homeostatic), the nucleus accumbens (hedonic), and the habenula (an important regulator of reward). In addition, the brain reward response to juice was studied. Participants included 12 patients with histological diagnosis of incurable cancer (solid tumours), a European Cooperative Oncology Group performance status of 0-2, and a ≥5% involuntary body weight loss from pre-illness over the previous 6 months and 12 non-cancer controls matched for age, sex, and race. RSFC between the hypothalamus, nucleus accumbens, and habenula and brain striatum activity as measured by functional MRI during juice reward delivery events were the main outcome measures. After adjusting for BMI and compared with matched controls, patients with C-WL were found to have reduced RSFC between the habenula and hypothalamus (P = 0.04) and between the habenula and nucleus accumbens (P = 0.014). Patients with C-WL also had reduced juice reward responses in the striatum compared with controls. In patients with C-WL, reduced connectivity between both homeostatic and hedonic brain regions and the habenula and reduced juice reward were observed. Further research is needed to establish the relevance of the habenula and striatum in C-WL. Published 2018. This article is

  3. Smads and insect hemimetabolan metamorphosis.

    Science.gov (United States)

    Santos, Carolina G; Fernandez-Nicolas, Ana; Belles, Xavier

    2016-09-01

    In contrast with Drosophila melanogaster, practically nothing is known about the involvement of the TGF-β signaling pathway in the metamorphosis of hemimetabolan insects. To partially fill this gap, we have studied the role of Smad factors in the metamorphosis of the German cockroach, Blattella germanica. In D. melanogaster, Mad is the canonical R-Smad of the BMP branch of the TGF-β signaling pathway, Smox is the canonical R-Smad of the TGF-β/Activin branch and Medea participates in both branches. In insects, metamorphosis is regulated by the MEKRE93 pathway, which starts with juvenile hormone (JH), whose signal is transduced by Methoprene-tolerant (Met), which stimulates the expression of Krüppel homolog 1 (Kr-h1) that acts to repress E93, the metamorphosis trigger. In B. germanica, metamorphosis is determined at the beginning of the sixth (final) nymphal instar (N6), when JH production ceases, the expression of Kr-h1 declines, and the transcription of E93 begins to increase. The RNAi of Mad, Smox and Medea in N6 of B. germanica reveals that the BMP branch of the TGF-β signaling pathway regulates adult ecdysis and wing extension, mainly through regulating the expression of bursicon, whereas the TGF-β/Activin branch contributes to increasing E93 and decreasing Kr-h1 at the beginning of N6, crucial for triggering adult morphogenesis, as well as to regulating the imaginal molt timing. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. CPLOAS_2 User Manual.

    Energy Technology Data Exchange (ETDEWEB)

    Sallaberry, Cedric Jean-Marie [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Helton, Jon C. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-05-01

    Weak link (WL)/strong link (SL) systems are important parts of the overall operational design of high - consequence systems. In such designs, the SL system is very robust and is intended to permit operation of the entire system under, and only under, intended conditions. In contrast, the WL system is intended to fail in a predictable and irreversible manner under accident conditions and render the entire system inoperable before an accidental operation of the SL system. The likelihood that the WL system will fail to d eactivate the entire system before the SL system fails (i.e., degrades into a configuration that could allow an accidental operation of the entire system) is referred to as probability of loss of assured safety (PLOAS). This report describes the Fortran 90 program CPLOAS_2 that implements the following representations for PLOAS for situations in which both link physical properties and link failure properties are time - dependent: (i) failure of all SLs before failure of any WL, (ii) failure of any SL before f ailure of any WL, (iii) failure of all SLs before failure of all WLs, and (iv) failure of any SL before failure of all WLs. The effects of aleatory uncertainty and epistemic uncertainty in the definition and numerical evaluation of PLOAS can be included in the calculations performed by CPLOAS_2. Keywords: Aleatory uncertainty, CPLOAS_2, Epistemic uncertainty, Probability of loss of assured safety, Strong link, Uncertainty analysis, Weak link

  5. Effect of yoga on self-rated visual discomfort in computer users.

    Science.gov (United States)

    Telles, Shirley; Naveen, K V; Dash, Manoj; Deginal, Rajendra; Manjunath, N K

    2006-12-03

    'Dry eye' appears to be the main contributor to the symptoms of computer vision syndrome. Regular breaks and the use of artificial tears or certain eye drops are some of the options to reduce visual discomfort. A combination of yoga practices have been shown to reduce visual strain in persons with progressive myopia. The present randomized controlled trial was planned to evaluate the effect of a combination of yoga practices on self-rated symptoms of visual discomfort in professional computer users in Bangalore. Two hundred and ninety one professional computer users were randomly assigned to two groups, yoga (YG, n = 146) and wait list control (WL, n = 145). Both groups were assessed at baseline and after sixty days for self-rated visual discomfort using a standard questionnaire. During these 60 days the YG group practiced an hour of yoga daily for five days in a week and the WL group did their usual recreational activities also for an hour daily for the same duration. At 60 days there were 62 in the YG group and 55 in the WL group. While the scores for visual discomfort of both groups were comparable at baseline, after 60 days there was a significantly decreased score in the YG group, whereas the WL group showed significantly increased scores. The results suggest that the yoga practice appeared to reduce visual discomfort, while the group who had no yoga intervention (WL) showed an increase in discomfort at the end of sixty days.

  6. Effect of Instrumentation Length and Instrumentation Systems: Hand Versus Rotary Files on Apical Crack Formation - An In vitro Study.

    Science.gov (United States)

    Devale, Madhuri R; Mahesh, M C; Bhandary, Shreetha

    2017-01-01

    Stresses generated during root canal instrumentation have been reported to cause apical cracks. The smaller, less pronounced defects like cracks can later propagate into vertical root fracture, when the tooth is subjected to repeated stresses from endodontic or restorative procedures. This study evaluated occurrence of apical cracks with stainless steel hand files, rotary NiTi RaCe and K3 files at two different instrumentation lengths. In the present in vitro study, 60 mandibular premolars were mounted in resin blocks with simulated periodontal ligament. Apical 3 mm of the root surfaces were exposed and stained using India ink. Preoperative images of root apices were obtained at 100x using stereomicroscope. The teeth were divided into six groups of 10 each. First two groups were instrumented with stainless steel files, next two groups with rotary NiTi RaCe files and the last two groups with rotary NiTi K3 files. The instrumentation was carried out till the apical foramen (Working Length-WL) and 1 mm short of the apical foramen (WL-1) with each file system. After root canal instrumentation, postoperative images of root apices were obtained. Preoperative and postoperative images were compared and the occurrence of cracks was recorded. Descriptive statistical analysis and Chi-square tests were used to analyze the results. Apical root cracks were seen in 30%, 35% and 20% of teeth instrumented with K-files, RaCe files and K3 files respectively. There was no statistical significance among three instrumentation systems in the formation of apical cracks (p=0.563). Apical cracks were seen in 40% and 20% of teeth instrumented with K-files; 60% and 10% of teeth with RaCe files and 40% and 0% of teeth with K3 files at WL and WL-1 respectively. For groups instrumented with hand files there was no statistical significance in number of cracks at WL and WL-1 (p=0.628). But for teeth instrumented with RaCe files and K3 files significantly more number of cracks were seen at WL than

  7. Effect of Instrumentation Length and Instrumentation Systems: Hand Versus Rotary Files on Apical Crack Formation – An In vitro Study

    Science.gov (United States)

    Mahesh, MC; Bhandary, Shreetha

    2017-01-01

    Introduction Stresses generated during root canal instrumentation have been reported to cause apical cracks. The smaller, less pronounced defects like cracks can later propagate into vertical root fracture, when the tooth is subjected to repeated stresses from endodontic or restorative procedures. Aim This study evaluated occurrence of apical cracks with stainless steel hand files, rotary NiTi RaCe and K3 files at two different instrumentation lengths. Materials and Methods In the present in vitro study, 60 mandibular premolars were mounted in resin blocks with simulated periodontal ligament. Apical 3 mm of the root surfaces were exposed and stained using India ink. Preoperative images of root apices were obtained at 100x using stereomicroscope. The teeth were divided into six groups of 10 each. First two groups were instrumented with stainless steel files, next two groups with rotary NiTi RaCe files and the last two groups with rotary NiTi K3 files. The instrumentation was carried out till the apical foramen (Working Length-WL) and 1 mm short of the apical foramen (WL-1) with each file system. After root canal instrumentation, postoperative images of root apices were obtained. Preoperative and postoperative images were compared and the occurrence of cracks was recorded. Descriptive statistical analysis and Chi-square tests were used to analyze the results. Results Apical root cracks were seen in 30%, 35% and 20% of teeth instrumented with K-files, RaCe files and K3 files respectively. There was no statistical significance among three instrumentation systems in the formation of apical cracks (p=0.563). Apical cracks were seen in 40% and 20% of teeth instrumented with K-files; 60% and 10% of teeth with RaCe files and 40% and 0% of teeth with K3 files at WL and WL-1 respectively. For groups instrumented with hand files there was no statistical significance in number of cracks at WL and WL-1 (p=0.628). But for teeth instrumented with RaCe files and K3 files

  8. Rn-Gas Concentration and Working Level Measurements Using SSNTD in Uranium Exploration Galleries Allouga Mine, Sinai, Egypt

    International Nuclear Information System (INIS)

    Abdel-Monem, A.A.; Hassan, S.F.; Abdel-Kader, F.H.; El-Naggar, A.M.; Essia, H.M.; Abdel-Hafez, A.A.

    2008-01-01

    Measurements of Rn-gas concentrations and Working Level (WL), were carried out in the U-exploration galleries at El- Allouga Mine, Sinai, Egypt by passive techniques (SSNTD) during the four seasons ( Summer, Fall, Winter and Spring) using four different detector types: CR-39, MK, CN-85 and LR-115.Twenty eight (28) stations were chosen for this purpose reflecting different environmental conditions as measurement sites within the galleries. The Rn-gas concentrations , in the summer period ranged from 25.86 to 44.2 pCi/l in the ventilated stations and from 488.98 to 611.16 pCi/l in the non-ventilated stations. In the fall period , the average Rn-gas concentrations in the ventilated stations ranged from 31.61 to 56.36 pCi/l while in the non-ventilated stations from 457.61 to 621.52 pCi/l. In the winter period, the average Rn-gas concentrations in the ventilated stations ranged from 27.59 to 66.45 pCi/l while in the non- ventilated stations from 499.09 to 603.81 pCi/l. In the spring the Rn-gas concentrations ranged from 30.8 to 46.77 pCi/l in the ventilated stations, whereas, in the non-ventilated stations from 404.06 to 445.18 pCi/l. The (WL), in the summer period, ranged from 0.143 to 0.247 in the ventilated sector and from 4.408 to 5.497 in the non-ventilated stations .In fall, the( WL) ranged from 0.166 to 0.295 in the ventilated stations and from 4.123 to 5.624 in the non-ventilated stations. In the winter, the (WL) ranged from 0.105 to 0.37 in the ventilated stations and from 4.138 to 5.26 in the non-ventilated stations. In the spring, the (WL) in the ventilated stations ranged from 0.152 to 0.241 and from 3.696 to 4.087 in the non-ventilated stations. These results indicate that: i)The low measured Rn gas and (WL) values in the ventilated stations reflect the effect of variations in meteorological conditions on (WL) determination where the air flow carries the Rn-gas before it decays and the daughters are plated onto the SSNTD . ii) The larger ranges for Rn

  9. Revised Rules for Concrete Bridges

    DEFF Research Database (Denmark)

    Thoft-Christensen, Palle; Jensen, F. M.; Middleton, C.

    This paper is based on research performed for the Highway Agency, London, UK under the project DPU/9/44 "Revision of Bridge Assessment Rules Based on Whole Life Performance: Concrete Bridges" It contains details of a methodology which can be used to generate Whole Life (WL) reliability profiles....... These WL reliability profiles may be used to establish revised rules for Concrete Bridges....

  10. Radon survey in Metropolitan Toronto schools

    International Nuclear Information System (INIS)

    Becker, E.; Moridi, R.

    1992-01-01

    The radon testing survey in Metropolitan Toronto public schools was the most intensive project of its kind ever undertaken in Canadian schools. It also included an extensive public education program on radiation and radon-in-schools. The radon levels at 632 schools were measured using the CAIRS Radon Monitors. Ninety percent of the locations measured were found to have a radon level equal to or less than 2 mWL. Two locations in two different schools were found to have a radon level at or above the Action Level (20 mWL). The remaining results were between the two extremes. Follow-up testing in those schools where more than 10 mWL of radon was found is in progress. (author)

  11. Excitation power dependence of photoluminescence spectra of GaSb type-II quantum dots in GaAs grown by droplet epitaxy

    Energy Technology Data Exchange (ETDEWEB)

    Kawazu, T., E-mail: KAWAZU.Takuya@nims.go.jp; Noda, T.; Sakuma, Y. [National Institute for Materials Science, 1-2-1 Sengen, Tsukuba, Ibaraki 305-0047 (Japan); Sakaki, H. [National Institute for Materials Science, 1-2-1 Sengen, Tsukuba, Ibaraki 305-0047 (Japan); Toyota Technological Institute, 2-12-1 Hisakata, Tempaku-ku, Nagoya 468-8511 (Japan)

    2016-04-15

    We investigated the excitation power P dependence of photoluminescence (PL) spectra of GaSb type-II quantum dots (QDs) in GaAs grown by droplet epitaxy. We prepared two QD samples annealed at slightly different temperatures (380 {sup o}C and 400 {sup o}C) and carried out PL measurements. The 20 {sup o}C increase of the annealing temperature leads to (1) about 140 and 60 times stronger wetting layer (WL) luminescence at low and high P, (2) about 45% large energy shift of QD luminescence with P, and (3) the different P dependence of the PL intensity ratio between the QD and the WL. These differences of the PL characteristics are explained by the effects of the WL.

  12. Reduced thermal quenching in indium-rich self-organized InGaN/GaN quantum dots

    KAUST Repository

    Elafandy, Rami T.

    2012-01-01

    Differences in optical and structural properties of indium rich (27), indium gallium nitride (InGaN) self-organized quantum dots (QDs), with red wavelength emission, and the two dimensional underlying wetting layer (WL) are investigated. Temperature dependent micro-photoluminescence (?PL) reveals a decrease in thermal quenching of the QDs integrated intensity compared to that of the WL. This difference in behaviour is due to the 3-D localization of carriers within the QDs preventing them from thermalization to nearby traps causing an increase in the internal quantum efficiency of the device. Excitation power dependent ?PL shows a slower increase of the QDs PL signal compared to the WL PL which is believed to be due to the QDs saturation. © 2012 American Institute of Physics.

  13. Serum Polychlorinated Biphenyls Increase and Oxidative Stress Decreases with a Protein-Pacing Caloric Restriction Diet in Obese Men and Women.

    Science.gov (United States)

    He, Feng; Zuo, Li; Ward, Emery; Arciero, Paul J

    2017-01-10

    The purposes were to compare the effects of a: (1) 12-week P-CR weight loss (WL) diet (Phase 1) between obese men and women and; (2) 52-week modified P-CR (mP-CR) vs. heart healthy (HH) weight maintenance (WM) diet (Phase 2) on serum PCBs and oxidative stress biomarkers (thiobarbituric acid reactive substances, TBARS; total antioxidant capacity, TAC) in 40 obese participants (men, n = 21; women, n = 19). Participants received dietary counseling and monitoring of compliance. PCBs, TBARS, and TAC were assessed at weeks -1 (CON), 12 (WL), and 64 (WM). Following WL (Week 12), concomitant with reductions in TBARS (0.24 ± 0.15 vs. 0.18 ± 0.11 µM; p 0.42, p < 0.05) and negatively correlated with body weight, fat mass, and abdominal fat ( r < -0.46, p < 0.02). Our results support mobilization of stored PCBs as well as enhanced redox status following a 12-week P-CR WL diet. Additionally, a 52-week mP-CR WM diet demonstrated an advantage in preventing weight gain relapse accompanied by an increase in circulating PCBs compared to a traditional HH diet.

  14. Atmospheric pressure-MOVPE growth of GaSb/GaAs quantum dots

    Science.gov (United States)

    Tile, Ngcali; Ahia, Chinedu C.; Olivier, Jaco; Botha, Johannes Reinhardt

    2018-04-01

    This study focuses on the growth of GaSb/GaAs quantum dots (QD) using an atmospheric pressure MOVPE system. For the best uncapped dots, the average dot height, base diameter and density are 5 nm, 45 nm and 4.5×1010 cm-2, respectively. Capping of GaSb QDs at high temperatures caused flattening and formation of thin inhomogeneous GaSb layer inside GaAs resulting in no obvious QD PL peak. Capping at low temperatures lead to the formation of dot-like features and a wetting layer (WL) with distinct PL peaks for QD and WL at 1097 nm and 983 nm respectively. Some of the dot-like features had voids. An increase in excitation power caused the QD and WL peaks to shift to higher energies. This is attributed to electrostatic band bending leading to triangular potential wells, typical of type-II alignment between GaAs and strained GaSb. Variable temperature PL measurements of the QD sample showed the decrease in the intensity of the WL peak to be faster than that of the QD peak as the temperature increased.

  15. Poster — Thur Eve — 55: An automated XML technique for isocentre verification on the Varian TrueBeam

    International Nuclear Information System (INIS)

    Asiev, Krum; Mullins, Joel; DeBlois, François; Liang, Liheng; Syme, Alasdair

    2014-01-01

    Isocentre verification tests, such as the Winston-Lutz (WL) test, have gained popularity in the recent years as techniques such as stereotactic radiosurgery/radiotherapy (SRS/SRT) treatments are more commonly performed on radiotherapy linacs. These highly conformal treatments require frequent monitoring of the geometrical accuracy of the isocentre to ensure proper radiation delivery. At our clinic, the WL test is performed by acquiring with the EPID a collection of 8 images of a WL phantom fixed on the couch for various couch/gantry angles. This set of images is later analyzed to determine the isocentre size. The current work addresses the acquisition process. A manual WL test acquisition performed by and experienced physicist takes in average 25 minutes and is prone to user manipulation errors. We have automated this acquisition on a Varian TrueBeam STx linac (Varian, Palo Alto, USA). The Varian developer mode allows the execution of custom-made XML script files to control all aspects of the linac operation. We have created an XML-WL script that cycles through each couch/gantry combinations taking an EPID image at each position. This automated acquisition is done in less than 4 minutes. The reproducibility of the method was verified by repeating the execution of the XML file 5 times. The analysis of the images showed variation of the isocenter size less than 0.1 mm along the X, Y and Z axes and compares favorably to a manual acquisition for which we typically observe variations up to 0.5 mm

  16. Influence of Weight Loss, Body Composition, and Lifestyle Behaviors on Plasma Adipokines: A Randomized Weight Loss Trial in Older Men and Women with Symptomatic Knee Osteoarthritis

    Directory of Open Access Journals (Sweden)

    Gary D. Miller

    2012-01-01

    Full Text Available Objective. To investigate effects of weight loss on adipokines and health measures in obese older adults with symptomatic knee osteoarthritis. Methods. Participants were randomly assigned to either weight loss (WL (men: 12, women: 14 or weight stable (WS group (men: 12, women: 13. WL intervention included meal replacements and structured exercise training. Measurements of leptin, adiponectin, soluble leptin receptor, lifestyle behaviors, and body composition were collected at baseline and 6 months. Univariate analysis of covariance was performed on 6 month variables, and Spearman and partial correlations were made between variables. Results. Weight loss was 13.0% and 6.7% in WL for men and women, respectively. Women in WL had lower whole body and trunk fat than WS. The leptin : adiponectin ratio was lower for women in WL than WS at 6 months, with no group differences in adipokines for men. Leptin and free leptin index correlated with body fat in both genders at baseline. Interestingly, only women showed reductions in leptin (P<0.100 and correlations between the percentage change leptin and trunk fat and the percentage changes in free leptin index with total fat and trunk fat. Partial correlations between 6 month adipokines after adjustments for covariates and group/time period show potential multivariate influences. Conclusions. In the presence of an effective weight loss intervention in older obese adults, there are significant relationships between weight and fat loss and leptin in women, but not men, suggesting gender-specific features of adipokine metabolism in this age group.

  17. Effect of yoga on self-rated visual discomfort in computer users

    Directory of Open Access Journals (Sweden)

    Deginal Rajendra

    2006-12-01

    Full Text Available Abstract Background 'Dry eye' appears to be the main contributor to the symptoms of computer vision syndrome. Regular breaks and the use of artificial tears or certain eye drops are some of the options to reduce visual discomfort. A combination of yoga practices have been shown to reduce visual strain in persons with progressive myopia. The present randomized controlled trial was planned to evaluate the effect of a combination of yoga practices on self-rated symptoms of visual discomfort in professional computer users in Bangalore. Methods Two hundred and ninety one professional computer users were randomly assigned to two groups, yoga (YG, n = 146 and wait list control (WL, n = 145. Both groups were assessed at baseline and after sixty days for self-rated visual discomfort using a standard questionnaire. During these 60 days the YG group practiced an hour of yoga daily for five days in a week and the WL group did their usual recreational activities also for an hour daily for the same duration. At 60 days there were 62 in the YG group and 55 in the WL group. Results While the scores for visual discomfort of both groups were comparable at baseline, after 60 days there was a significantly decreased score in the YG group, whereas the WL group showed significantly increased scores. Conclusion The results suggest that the yoga practice appeared to reduce visual discomfort, while the group who had no yoga intervention (WL showed an increase in discomfort at the end of sixty days.

  18. Cognitive function predicts 24-month weight loss success after bariatric surgery.

    Science.gov (United States)

    Spitznagel, Mary Beth; Alosco, Michael; Strain, Gladys; Devlin, Michael; Cohen, Ronald; Paul, Robert; Crosby, Ross D; Mitchell, James E; Gunstad, John

    2013-01-01

    Clinically significant cognitive impairment, particularly in attention/executive and memory function, is found in many patients undergoing bariatric surgery. These difficulties have previously been linked to decreased weight loss 12 months after surgery, but more protracted examination of this relationship has not yet been conducted. The present study prospectively examined the independent contribution of cognitive function to weight loss 24 months after bariatric surgery. Given the rapid rate of cognitive improvement observed after surgery, postoperative cognitive function (i.e., cognition 12 weeks after surgery, controlling for baseline cognition) was expected to predict lower body mass index (BMI) and higher percent total weight loss (%WL) at 24-month follow-up. Data were collected by 3 sites of the Longitudinal Assessment of Bariatric Surgery (LABS) parent project. Fifty-seven individuals enrolled in the LABS project who were undergoing bariatric surgery completed cognitive evaluation at baseline, 12 weeks, and 24 months. BMI and %WL were calculated for 24-month postoperative follow-up. Better cognitive function 12 weeks after surgery predicted higher %WL and lower BMI at 24 months, and specific domains of attention/executive and memory function were robustly related to decreased BMI and greater %WL at 24 months. Results show that cognitive performance shortly after bariatric surgery predicts greater long-term %WL and lower BMI 24 months after bariatric surgery. Further work is needed to clarify the degree to which this relationship is mediated by adherence to postoperative guidelines. Copyright © 2013 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

  19. A pilot study on the functional performance and acceptability of an innovative female condom (Wondaleaf® in Malaysia

    Directory of Open Access Journals (Sweden)

    Ting RS

    2018-01-01

    Full Text Available Rachel Sing-Kiat Ting,1 Ee-Lynn Wong,2 Jessie Koh-Sing Tnay3 1School of Sociology, China University of Political Sciences and Law, Beijing, China; 2InPsych Psychological and Counselling Services, Kuala Lumpur, 3Institute of Borneo Studies, Universiti Malaysia Sarawak, Sarawak, Malaysia Background: Female condom (FC has been available for over 30 years, but it still lacks wide acceptability. To overcome misdirection and invagination occurring in FC and to provide a wider area of protection, Wondaleaf® (WL, a new-generation adhesive FC, was recently invented. This pioneering study sought to assess the acceptability and functional performance of WL among Malaysian women. Methods: A mixed method survey was conducted in three cities of Malaysia, recruiting sexually active heterosexual women, aged 18–50, by snowball sampling method. Participants were provided with WL and initially surveyed to rate its performance in five coital usages over 2 months. After that, the participants underwent a second survey to rate their satisfaction and acceptability toward WL. Descriptive statistics on clinical failure rates were tabulated with correlational analysis performed to identify major variables contributing to WL’s functional performance and acceptability. Results: Out of the 51 enrolled participants, 31 women completed the required surveys. WL’s total clinical failure rate was 2.60% (out of 155 condom uses with above-average ratings of functional performance. The ease of use significantly correlated with ratings of no slippage and no misdirection. The confidence in WL’s safety features significantly correlated with a sense of empowerment and protection. Conclusion: WL has a relatively low risk of clinical failures and an overall favorable acceptability among Malaysian women. However, this study also showed that its future usage largely depends on partner acceptability. It may have the potential of complementing the existing barrier toward

  20. SU-E-J-48: Imaging Origin-Radiation Isocenter Coincidence for Linac-Based SRS with Novalis Tx

    International Nuclear Information System (INIS)

    Geraghty, C; Workie, D; Hasson, B

    2015-01-01

    Purpose To implement and evaluate an image-based Winston-Lutz (WL) test to measure the displacement between ExacTrac imaging origin and radiation isocenter on a Novalis Tx system using RIT V6.2 software analysis tools. Displacement between imaging and radiation isocenters was tracked over time. The method was applied for cone-based and MLC-based WL tests. Methods The Brainlab Winston-Lutz phantom was aligned to room lasers. The ExacTrac imaging system was then used to detect the Winston- Lutz phantom and obtain the displacement between the center of the phantom and the imaging origin. EPID images of the phantom were obtained at various gantry and couch angles and analyzed with RIT calculating the phantom center to radiation isocenter displacement. The RIT and Exactrac displacements were combined to calculate the displacement between imaging origin and radiation isocenter. Results were tracked over time. Results Mean displacements between ExacTrac origin and radiation isocenter were: VRT: −0.1mm ± 0.3mm, LNG: 0.5mm ± 0.2mm, LAT: 0.2mm ± 0.2mm (vector magnitude of 0.7 ± 0.2mm). Radiation isocenter was characterized by the mean of the standard deviations of the WL phantom displacements: σVRT: 0.2mm, σLNG: 0.4mm, σLAT: 0.6mm. The linac couch base was serviced to reduce couch walkout. This reduced σLAT to 0.2mm. These measurements established a new baseline of radiation isocenter-imaging origin coincidence. Conclusion The image-based WL test has ensured submillimeter localization accuracy using the ExacTrac imaging system. Standard deviations of ExacTrac-radiation isocenter displacements indicate that average agreement within 0.3mm is possible in each axis. This WL test is a departure from the tradiational WL in that imaging origin/radiation isocenter agreement is the end goal not lasers/radiation isocenter

  1. Preliminary findings radon daughter levels in structures constructed on reclaimed Florida phosphate land

    International Nuclear Information System (INIS)

    1975-09-01

    Preliminary results are reported from a survey of the radon daughter levels in structures in Polk County, Florida, built on reclaimed phosphate tailings containing various amounts of 226 Ra. The structures surveyed consisted primarily of private dwellings although a few office buildings were also surveyed. Track-etch films and TLD air samplers were used to measure the levels of radon daughters within the structures and in structures built on non-phosphate land. Radiation levels were converted to WL units (the working level (WL) unit is defined as the potential α energy from the short-lived daughters of Rn which will produce 1.3 x 10 5 MeV in one liter of air). The highest observed level in any structure was 0.2 WL. Possible health hazards to long-time occupants are discussed

  2. Elliot Lake progress report

    International Nuclear Information System (INIS)

    Findlay, W.; Scott, A.S.

    1980-01-01

    The intent of the Elliot Lake remedial program is to identify houses in Elliot Lake with annual average WL's in excess of 0.02, discover the routes of radon entry into identified houses and close enough of them to reduce the annual average WL to an acceptable level, and to demonstrate that the annual average WL is below 0.02 in houses where remedial work was not thought necessary as well as in houses where remedial work has been completed. The remedial program is organized into two subprograms, the survey program and the remedial action program. By December 31, 1979 more than 17000 survey measurements had been carried out, identifying 157 houses where remedial action was required and confirming that no action was needed in 413 houses. Remedial work had been completed on 98 houses

  3. Radon hazard from caisson and tunnel construction in Kong Kong

    International Nuclear Information System (INIS)

    Lam, W.K.; Tsin, T.W.; Ng, T.P.

    1988-01-01

    A possible occupational risk of caisson and tunnel excavation in Hong Kong results from the inhalation of natural radon daughters. In this study radon daughter concentrations ranging from 0.001 to 71.4 WL were recorded in caissons of various dimensions and from 0.03 to 0.95 WL in tunnels over 1 km in length under construction (ICRP exposure limit being 0.4 WL). There was clear indication of increased radon daughter accumulation in confined and unventilated areas and in unventilated caissons an exponential increase of radon daughter concentration with the ratio of depth to cross-sectional area was observed (r=0.9). The study revealed a potential radiation hazard facing underground construction workers and this is being examined by an ongoing epidemiological cohort study: meanwhile environmental control should be improved. (UK)

  4. Hip abductors and thigh muscles strength ratios and their relation to electromyography amplitude during split squat and walking lunge exercises

    Directory of Open Access Journals (Sweden)

    Petr Stastny

    2015-06-01

    Full Text Available Background: The hip abductors (HAB, quadriceps (Q and hamstrings (H reciprocal strength ratios are predictors of electromyography (EMG amplitude during load carrying walking at moderate intensity. Therefore, these strength ratios might predict also the EMG during the exercises as walking lunge (WL or split squat (SSq at submaximal intensity. Objective: To determine whether the EMG amplitude of vastus mediali (VM, vastus laterali (VL, biceps femoris (BF and gluteus medius (Gmed is associated with muscle strength ratio during SSqs and WLs. To determine whether the EMG amplitude differs between individuals with HAB/H ratio above and below one and between individuals with H/Q or HAB/Q ratio above and below 0.5 during SSqs and WLs. Methods: 17 resistance-trained men (age 29.6 ± 4.6 years with at least 3 years of strength training performed in cross-sectional design 5 s maximal voluntary isometric contractions (MVIC on an isokinetic dynamometer for knee extension, knee flexion, and hip abduction. The MVIC was used to normalize the EMG signal and estimate the individual strength ratios. Than participants performed WL and SSq for a 5 repetition maximum, to find out muscle activity at submaximal intensity of exercise. Results: The H/Q ratio was associated by Kendall's tau (τ with VM (τ = .33 and BF (τ = -.71 amplitude, HAB/Q ratio was associated with BF (τ = -.43 and Gmed (τ = .38 amplitude, as well as HAB/H was associated with VM (τ = -.41 and Gmed (τ = .74 amplitude. ANOVA results showed significant differences between SSq and WL (F(4, 79 = 10, p < .001, ηp2 = .34 in Gmed amplitude, where WL resulted in higher Gmed amplitude compared to SSq. Other significant differences were found between H/Q groups (F(4, 29 = 3, p = .04, ηp2 = .28 in VM and Gmed amplitude, where group with H/Q > 0.5 showed higher VMO amplitude and lower Gmed amplitude. Furthermore, significant difference was found

  5. Analysis of the width ratio and wear rate of maxillary anterior teeth in the Korean population.

    Science.gov (United States)

    Oh, Yeon-Ah; Yang, Hong-So; Park, Sang-Won; Lim, Hyun-Pil; Yun, Kwi-Dug; Park, Chan

    2017-04-01

    The purpose of this study was to compare the width ratio of maxillary anterior teeth according to age in the Korean population and to evaluate the maxillary central incisor width-to-length (W/L) ratio, given differences in age and gender. Ninety-three Korean adults were divided into 3 groups (n = 31) by age. Group I was 20 - 39 years old, Group II was 40 - 59 years old, and Group III was over 60 years of age. After taking an impression and a cast model of the maxillary arch, the anterior teeth width ratio and central incisor W/L ratio were calculated from standard digital images of the cast models using a graph paper with a digital single lens reflex (DSLR) camera. The calculated ratios were compared among all groups and central incisor W/L ratio were analyzed according to age and gender. All comparative data were statistically analyzed with one-sample t-tests, one-way ANOVAs with Tukey tests, and independent t-tests. No significant differences in maxillary anterior teeth ratios were found among the age groups. The maxillary central incisor W/L ratios in Group III were the greatest and were significantly higher than those in the other groups. The central incisor W/L ratio of men was higher than that of women in Group II. Maxillary anterior teeth width ratios were similar in all age groups in the Korean population. The maxillary central incisor was observed as worn teeth in the group over 60 years of age, and a significant difference between genders was found in 40 to 50 year olds.

  6. Evaluation of experiences in long-term radon and radon-daughter measurements

    International Nuclear Information System (INIS)

    Young, J.A.; Jackson, P.O.; Thomas, V.W.

    1982-12-01

    Pacific Northwest Laboratory (PNL) is performing side-by-side measurements of radon and radon daughter concentrations using several instruments and techniques, and is comparing these measurements with side-by-side measurements made by other investigators at other locations. The standard deviation of the differences between the (natural) logarithms of the Terradex Track Etch radon concentrations and the logarithms of the Radon Progency Integrating Sampling Units (RPISU) radon daughter concentrations (S.D.-ln) measured in 50 buildings in Edgemont, South Dakota, was 0.37. Using this S.D.-ln, it can be calculated that if the Track Etch radon daughter concentration is 0.010 WL there should be only a 14% probability that the RPISU average would be greater than 0.015 WL, and only a 3% probability tht the RPISU average would be greater than 0.020 WL. If buildings had been cleared from remedial action when the Track Etch averages were less than 0.10 WL, then about 61% of the buildings would have been cleared from remedial action, and only a few percent of these buildings would have actually had average RPISU concentrations greater than 0.015 WL. The S.D.-ln between the Track Etch radon measurements and the RPISU radon daughter measurements made by ALARA at Grand Junction, the PERM radon measurements and the MOD-225 radon daughter measurements made by Mound Facility at Canonsburg and Middlesex, and the PERM and Track Etch radon measurements made by Mound Facility at Salt Lake City were similar to the S.D.-ln between the Track Etch radon measurements and the RPISU radon daughter measurements at Edgemont

  7. Safety and efficacy of radioactive seed localization with I-125 prior to lumpectomy and/or excisional biopsy

    International Nuclear Information System (INIS)

    Sung, Janice S.; King, Valencia; Thornton, Cynthia M.; Brooks, Jennifer D.; Fry, Charles W.; El-Tamer, Mahmoud; Dauer, Lawrence T.; Brogi, Edi; St Germain, Jean M.; Morris, Elizabeth A.

    2013-01-01

    Purpose: To evaluate the safety and efficacy of pre-operative I-125 radioactive seed localization (RSL) as an alternative to wire localization (WL). Methods: A waiver was granted by the institutional review board for this HIPAA compliant study. Review of 356 consecutive single site nonpalpable mammographic and ultrasound guided I-125 RSLs done between November 2011 and April 2012 was conducted. Preoperative mammograms and specimen radiographs were reviewed for seed-target distance, lesion location, and target/seed removal. During a brief surgical training period, 35 of 356 women had both RSL and wire localization (WL) of the same lesion. Chi-square and single sample t-tests were used to compare margin status and duration of procedures. Results: Of the 356 RSLs, 303 (85.1%) were performed ≥1 day before surgery. Mammographic guidance was used in 330 (93%) and ultrasound in 26 (7%). Mean seed to target distance was 1 mm (range 0–20 mm); all targeted lesions were retrieved. In 31 women in whom mammographic guidance was used for both RSL and WL, median procedure time was not significantly different (RSL 9.0 min; WL 7.0 min; p = 0.91), and median seed migration distance was <1 mm (range 0–15 mm). No difference was detected between margin status with RSL alone versus WL (p = 0.40 and p = 0.65 for positive and <1 mm margins, respectively). Two adverse events occurred requiring an additional wire/surgery. Conclusion: RSL ≥ 1 day before surgery is a safe effective procedure for pre-operative localization, with few adverse events and surgical outcomes comparable to those achieved with wire localization

  8. The Impact of Blue Light Cystoscopy with Hexaminolevulinate (HAL) on Progression of Bladder Cancer - A New Analysis.

    Science.gov (United States)

    Kamat, Ashish M; Cookson, Michael; Witjes, J Alfred; Stenzl, Arnulf; Grossman, H Barton

    2016-04-27

    Background: The International Bladder Cancer Group (IBCG) recently proposed a new definition of disease progression in non-muscle invasive bladder cancer (NMIBC), including change in T-stage, change to T2 or higher or change from low to high grade. Objective: To establish whether blue light cystoscopy with hexaminolevulinate (HAL) impacts the rate of progression and time to progression using the revised definition. Methods: An earlier long-term follow-up of a controlled Phase III study reported outcomes following blue light cystoscopy with HAL (255 patients) or white light (WL) cystoscopy (261 patients) in NMIBC patients. The data was re-analysed according to the new definition. Results: In the original analysis, after 4.5 years (median), eight HAL and 16 WL patients were deemed to have progressed (transition from NMIBC to muscle invasive bladder cancer, (T2-4)). According to the new definition, additional patients in both groups were found to have progressed: 31 (12.2%) HAL vs 46 (17.6%) WL ( p  = 0.085) with four (1.6%) HAL and 11 (4.2%) WL patients progressing from Ta to CIS. Time to progression was longer in the HAL group ( p  = 0.05). Conclusions: Applying the new IBCG definition there was a trend towards a lower rate of progression in HAL patients, particularly in those progressing from Ta to CIS. Time to progression was significantly prolonged. This suggests that patients should receive blue light cystoscopy with HAL rather than WL at resection. Adoption of the new definition could allow more patients at risk of progression to be treated appropriately earlier.

  9. Radon and thoron progeny measurements using a portable radon sniffer

    International Nuclear Information System (INIS)

    Efendi, Z.; Jennings, P.

    1993-01-01

    A flexible version of the two-count method has been developed for use in rapid, inexpensive measurements of radon and thoron progeny working levels in residential and industrial premises in the Perth Metropolitan Area. The Method is adapted for use with a simple radon sniffer based on a low speed pump and an alpha counter. The flexibility of the method derives from the software, where some freedom is permitted in the selection of sampling times and post sampling analysis of the filters. This method has been tested on a variety of radioactive materials and it gives consistent, reliable results over a wide range of working levels. The results of a survey of Rn(222) and Rn(220) progeny levels in dwellings within the Perth Metropolitan Area are reported. This study shows that the mean concentration of indoor Rn(222) progeny was 4.7 mWL (17.4 Bq m -3 EEC) up to 23.3 mWL (86.4 Bq m -3 EEC). The mean thoron progeny concentration was 8.2 mWL (2.25 Bq m -3 EEC) with a range from 1 mWL (0.27 Bq m -3 EEC) to 64.5 mWL (17.74 Bq m -3 EEC). Using conversion factors of 0.061 mSv Bq -1 m -3 for Rn(222) progeny and 0.29 mSv Bq -1 m -3 for Rn(220) progeny respectively (UNSCEAR, 1982), it is estimated the average annual effective dose equivalent is 1.1 mSv for Rn(2220 and 0.6 mSv for Rn(220) respectively. 22 refs., 4 tabs., 1 fig

  10. Prevalidation trial for a novel in vitro eye irritation test using the reconstructed human cornea-like epithelial model, MCTT HCE™.

    Science.gov (United States)

    Yang, Hyeri; Kim, Da-Eun; Jang, Won-Hee; An, Susun; Cho, Sun-A; Jung, Mi-Sook; Lee, Ji Eun; Yeo, Kyung-Wook; Koh, Sang Bum; Jeong, Tae-Cheon; Kang, Mi-Jeong; Chun, Young-Jin; Lee, Su-Hyon; Lim, Kyung-Min; Bae, SeungJin

    2017-03-01

    Here, we report the results of a prevalidation trial for an in vitro eye irritation test (EIT) using the reconstructed human cornea-like epithelium, MCTT HCE™. The optimal cutoff to determine irritation in the prediction model was established at 35% with the receiver operation characteristics(ROC) curve for 126 substances. Within-lab(WL) and between-lab(BL) reproducibility was tested for 20 reference substances by 3 participating laboratories. Viability data described by mean±SD or ±1/2 difference between duplicate wells, and scatter plots, demonstrated the WL/BL consistency. WL/BL concordance with the binary decision, whether non-irritant or irritant was estimated to be 85-95% and 95%, respectively. WL/BL reproducibility of viability data was further supported by a strong correlation(ICC, r>0.9). WL/BL agreement of binary decisions was also examined by Fleiss' Kappa statistics, which showed a strong level of agreement (>0.78), nevertheless weaker than the reproducibility of the viability. The EIT with MCTT HCE™ exhibited a sensitivity of 82.2% (60/73), a specificity of 81.1% (43/53), and an accuracy of 81.8% (103/126) for 126 reference substances (for liquids; a sensitivity of 100% (47/47), a specificity of 70.6% (24/34), and an accuracy of 87.7% (71/81), and for solids, a sensitivity of 50% (13/26), a specificity of 100% (19/19), and an accuracy of 71.1% (32/45), suggesting that the accuracy is satisfactory but the sensitivity needs improvement, which shall be addressed through correcting the poor sensitivity for solid substances in future full validation trials. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. IRIS , Hinode , SDO , and RHESSI Observations of a White Light Flare Produced Directly by Non-thermal Electrons

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kyoung-Sun [Hinode Science Center, National Astronomical Observatory of Japan (NAOJ), 2-21-1, Osawa, Mitaka, Tokyo 181-8588 (Japan); Imada, Shinsuke [Institute for Space–Earth Environmental Research (ISEE), Nagoya University, Furo-cho, Chikusa-ku, Nagoya 466-8550 (Japan); Watanabe, Kyoko [National Defense Academy of Japan, 1-10-20 Hashirimizu, Yokosuka 239-8686 (Japan); Bamba, Yumi [Hinode team, ISAS/JAXA, 3-1-1 Yoshinodai, Chuo-ku, Sagamihara, Kanagawa 252-5210 (Japan); Brooks, David H., E-mail: ksun.lee@nao.ac.jp [College of Science, George Mason University, 4400 University Drive, Fairfax, VA 22030 (United States)

    2017-02-20

    An X1.6 flare occurred in active region AR 12192 on 2014 October 22 at 14:02 UT and was observed by Hinode , IRIS , SDO , and RHESSI . We analyze a bright kernel that produces a white light (WL) flare with continuum enhancement and a hard X-ray (HXR) peak. Taking advantage of the spectroscopic observations of IRIS and Hinode /EIS, we measure the temporal variation of the plasma properties in the bright kernel in the chromosphere and corona. We find that explosive evaporation was observed when the WL emission occurred, even though the intensity enhancement in hotter lines is quite weak. The temporal correlation of the WL emission, HXR peak, and evaporation flows indicates that the WL emission was produced by accelerated electrons. To understand the WL emission process, we calculated the energy flux deposited by non-thermal electrons (observed by RHESSI ) and compared it to the dissipated energy estimated from a chromospheric line (Mg ii triplet) observed by IRIS . The deposited energy flux from the non-thermal electrons is about (3–7.7) × 10{sup 10} erg cm{sup −2} s{sup −1} for a given low-energy cutoff of 30–40 keV, assuming the thick-target model. The energy flux estimated from the changes in temperature in the chromosphere measured using the Mg ii subordinate line is about (4.6–6.7) × 10{sup 9} erg cm{sup −2} s{sup −1}: ∼6%–22% of the deposited energy. This comparison of estimated energy fluxes implies that the continuum enhancement was directly produced by the non-thermal electrons.

  12. Sea-level rise impacts on the temporal and spatial variability of extreme water levels: A case study for St. Peter-Ording, Germany

    Science.gov (United States)

    Santamaria-Aguilar, S.; Arns, A.; Vafeidis, A. T.

    2017-04-01

    Both the temporal and spatial variability of storm surge water level (WL) curves are usually not taken into account in flood risk assessments as observational data are often scarce. In addition, sea-level rise (SLR) can further affect the variability of WLs. We analyze the temporal and spatial variability of the WL curve of 75 historical storm surge events that have been numerically simulated for St. Peter-Ording at the German North Sea coast, considering the effects induced by three SLR scenarios (RCP 4.5, RCP 8.5, and a RCP 8.5 high end scenario). We assess potential impacts of these scenarios on two parameters related to flooding: overflow volumes and fullness. Our results indicate that due to both the temporal and spatial variability of those events the resulting overflow volume can be two or even three times greater. We observe a steepening of the WL curve with an increase of the tidal range under the three SLR scenarios, although SLR induced effects are relatively higher for the RCP 4.5. The steepening of the WL curve with SLR produces a reduction of the fullness, but the changes in overflow volumes also depend on the magnitude of the storm surge event.

  13. Calorie Estimation in Adults Differing in Body Weight Class and Weight Loss Status.

    Science.gov (United States)

    Brown, Ruth E; Canning, Karissa L; Fung, Michael; Jiandani, Dishay; Riddell, Michael C; Macpherson, Alison K; Kuk, Jennifer L

    2016-03-01

    Ability to accurately estimate calories is important for weight management, yet few studies have investigated whether individuals can accurately estimate calories during exercise or in a meal. The objective of this study was to determine if accuracy of estimation of moderate or vigorous exercise energy expenditure and calories in food is associated with body weight class or weight loss status. Fifty-eight adults who were either normal weight (NW) or overweight (OW), and either attempting (WL) or not attempting weight loss (noWL), exercised on a treadmill at a moderate (60% HRmax) and a vigorous intensity (75% HRmax) for 25 min. Subsequently, participants estimated the number of calories they expended through exercise and created a meal that they believed to be calorically equivalent to the exercise energy expenditure. The mean difference between estimated and measured calories in exercise and food did not differ within or between groups after moderate exercise. After vigorous exercise, OW-noWL overestimated energy expenditure by 72% and overestimated the calories in their food by 37% (P food compared with both WL groups (P food. There was a wide range of underestimation and overestimation of calories during exercise and in a meal. Error in calorie estimation may be greater in overweight adults who are not attempting weight loss.

  14. Losing weight for a better health: Role for the gut microbiota

    Directory of Open Access Journals (Sweden)

    Maria Carlota Dao

    2016-04-01

    Full Text Available In recent years, there have been several reviews on gut microbiota, obesity and cardiometabolism summarizing interventions that may impact the gut microbiota and have beneficial effects on the host (some examples include [1–3]. In this review we discuss how the gut microbiota changes with weight loss (WL interventions in relation to clinical and dietary parameters. We also evaluate available evidence on the heterogeneity of response to these interventions. Two important questions were generated in this regard: 1 Can response to an intervention be predicted? 2 Could pre-intervention modifications to the gut microbiota optimize WL and metabolic improvement? Finally, we have delineated some recommendations for future research, such as the importance of assessment of diet and other environmental exposures in WL intervention studies, and the need to shift to more integrative approaches of data analysis.

  15. Experience with digital acoustic monitoring systems for PWRs and BWRs

    International Nuclear Information System (INIS)

    Olma, B.J.

    1998-01-01

    Substantial progress could be reached both in system technics and in application of digital acoustic monitoring systems for assessing mechanical integrity of reactor primary systems. For the surveillance of PWRs and BWRs during power operation of the plants, acoustic signals of Loose Parts Monitoring System sensors are continuously monitored for signal bursts associated with metallic impacts. ISTec/GRS experience with its digital systems MEDEA and RAMSES has shown that acoustic signature analysis is very successful for detecting component failures at an early stage. Methods for trending and classification of digital burst signals are shown, experience with their practical use will be presented. (author)

  16. SÈNECA, L. A.: Tragèdies, edició crítica de Tomàs Martínez Romero, 2 volums, Barcelona, Barcino, 1995 («Els Nostres Clàssics», Col.lecció B, núm. 14-15)

    OpenAIRE

    Pujol i Gómez, Josep

    1998-01-01

    Obra ressenyada: L. A. SÈNECA; edició crítica de Tomàs MARTÍNEZ ROMERO, Tragèdies. Barcelona: Barcino, 1995. Tomàs Martínez fa una edició crítica de les traduccions catalanes medievals de les següents tragèdies de Sèneca: 'Hercules furens', 'Thyestes', 'Thebais (Phoenissiae)', 'Hippolytus (Phaedra)' 'Oedipus', 'Troades', 'Medea' i 'Agamemnon'. A banda de l'edició, tracta qüestions com la difusió tardomedieval de Sèneca a la corona d'Aragó, la bibliografia sobre la diversitat dels mètodes d...

  17. Timeline of changes in appetite during weight loss with a ketogenic diet

    OpenAIRE

    Nymo, Siren

    2017-01-01

    Background/objective: Diet-induced weight loss (WL) leads to increased hunger and reduced fullness feelings, increased ghrelin and reduced satiety peptides concentration (glucagon-like peptide-1 (GLP-1), cholecystokinin (CCK) and peptide YY (PYY)). Ketogenic diets seem to minimise or supress some of these responses. The aim of this study was to determine the timeline over which changes in appetite occur during progressive WL with a ketogenic very-low-energy diet (VLED). Subjects/methods: T...

  18. Initial Weight Loss after Restrictive Bariatric Procedures May Predict Mid-Term Weight Maintenance: Results From a 12-Month Pilot Trial

    OpenAIRE

    Nikolić, Marko; Kruljac, Ivan; Kirigin, Lora; Mirošević, Gorana; Ljubičić, Neven; Nikolić, Borka Pezo; Bekavac-Bešlin, Miroslav; Budimir, Ivan; Vrkljan, Milan

    2015-01-01

    Background: Bariatric procedures are effective options for weight loss (WL) in the morbidly obese. However, some patients fail to lose any weight after bariatric surgery, and mid-term weight maintenance is variable. The aim of this study was to investigate whether initial WL could predict mid-term weight maintenance. ----- Methods: Eighty patients were enrolled, of whom 44 were treated with the BioEnterics Intragastric Balloon (BIB), 21 with laparoscopic adjustable gastric lap-banding (LAGB),...

  19. Accelerating the Whiteshell Laboratories Decommissioning Through the Implementation of a Projectized and Delivery-Focused Organization - 13074

    Energy Technology Data Exchange (ETDEWEB)

    Wilcox, Brian; Mellor, Russ; Michaluk, Craig [Atomic Energy of Canada Limited, Whiteshell Laboratories, Pinawa, Manitoba (Canada)

    2013-07-01

    Whiteshell Laboratories (WL) is a nuclear research site in Canada that was commissioned in 1964 by Atomic Energy of Canada Limited. It covers a total area of approximately 4,375 hectares (10,800 acres) and includes the main campus site, the Waste Management Area (WMA) and outer areas of land identified as not used for or impacted by nuclear development or operations. The WL site employed up to 1100 staff. Site activities included the successful operation of a 60 MW organic liquid-cooled research reactor from 1965 to 1985, and various research programs including reactor safety research, small reactor development, fuel development, biophysics and radiation applications, as well as work under the Canadian Nuclear Fuel Waste Management Program. In 1997, AECL made a business decision to discontinue research programs and operations at WL, and obtained government concurrence in 1998. The Nuclear Legacy Liabilities Program (NLLP) was established in 2006 by the Canadian Government to remediate nuclear legacy liabilities in a safe and cost effective manner, including the WL site. The NLLP is being implemented by AECL under the governance of a Natural Resources Canada (NRCan)/AECL Joint Oversight Committee (JOC). Significant progress has since been made, and the WL site currently holds the only Canadian Nuclear Safety Commission (CNSC) nuclear research site decommissioning license in Canada. The current decommissioning license is in place until the end of 2018. The present schedule planned for main campus decommissioning is 30 years (to 2037), followed by institutional control of the WMA until a National plan is implemented for the long-term management of nuclear waste. There is an impetus to advance work and complete decommissioning sooner. To accomplish this, AECL has added significant resources, reorganized and moved to a projectized environment. This presentation outlines changes made to the organization, the tools implemented to foster projectization, and the benefits

  20. Probing the WL'WH and WR'WH interactions at LHC

    International Nuclear Information System (INIS)

    Bao Shoushan; Li Honglei; Si Zongguo; Zhou Yufeng

    2011-01-01

    Many new physics models predict the existence of TeV-scale charged gauge boson W ' together with Higgs-boson(s). We study the W ' WH interaction and explore the angular distribution of charged leptons to distinguish W R ' WH from W L ' WH in the pp→HW→bblν process at the LHC. It is found that a new type forward-backward asymmetry (A FB ) relating to the angle between the direction of the charged lepton in the W rest frame and that of the reconstructed W ' in the laboratory frame is useful to investigate the properties of W ' WH interaction. We analyze the standard model backgrounds and develop a set of cuts to highlight the signal and suppress the backgrounds at LHC. We find that A FB can reach 0.03(-0.07) for W R ' (W L ' ) production at √(S)=14 TeV.

  1. Decommissioning of AECL Whiteshell laboratories - 16311

    International Nuclear Information System (INIS)

    Koroll, Grant W.; Bilinsky, Dennis M.; Swartz, Randall S.; Harding, Jeff W.; Rhodes, Michael J.; Ridgway, Randall W.

    2009-01-01

    Whiteshell Laboratories (WL) is a Nuclear Research and Test Establishment near Winnipeg, Canada, operated by AECL since the early 1960's and now under decommissioning. WL occupies approximately 4400 hectares of land and employed more than 1000 staff up to the late-1990's, when the closure decision was made. Nuclear facilities at WL included a research reactor, hot cell facilities and radiochemical laboratories. Programs carried out at the WL site included high level nuclear fuel waste management research, reactor safety research, nuclear materials research, accelerator technology, biophysics, and industrial radiation applications. In preparation for decommissioning, a comprehensive environmental assessment was successfully completed [1] and the Canadian Nuclear Safety Commission issued a six-year decommissioning licence for WL starting in 2003 - the first decommissioning licence issued for a Nuclear Research and Test Establishment in Canada. This paper describes the progress in this first six-year licence period. A significant development in 2006 was the establishment of the Nuclear Legacy Liabilities Program (NLLP), by the Government of Canada, to safely and cost effectively reduce, and eventually eliminate the nuclear legacy liabilities and associated risks, using sound waste management and environmental principles. The NLLP endorsed an accelerated approach to WL Decommissioning, which meant advancing the full decommissioning of buildings and facilities that had originally been planned to be decontaminated and prepared for storage-with-surveillance. As well the NLLP endorsed the construction of enabling facilities - facilities that employ modern waste handling and storage technology on a scale needed for full decommissioning of the large radiochemical laboratories and other nuclear facilities. The decommissioning work and the design and construction of enabling facilities are fully underway. Several redundant non-nuclear buildings have been removed and redundant

  2. The Effects of rhBMP-2 Used for Spinal Fusion on Spinal Cord Pathology After Traumatic Injury

    Science.gov (United States)

    2009-07-29

    1219-1224; discussion 1225. Basso DM , Beattie MS, Bresnahan JC (1995) A sensitive and reliable locomotor rating scale for open field testing in rats...usage of rhBMP-2 in the anterior cervical spine. Spine 31:2813-2819. Stuesse SL, Crisp T, McBurney DL, Schechter JB, Lovell JA, Cruce WL (2001...250-256. Stuesse SL, Crisp T, McBurney DL, Schechter JB, Lovell JA, Cruce WL (2001) Neuropathic pain in aged rats: behavioral responses and

  3. Department of Defense Abstracts of Phase 2 Awards 1991

    Science.gov (United States)

    1991-01-01

    Rt.2, Box188 Office: NAVAIR La Honda , CA 94020 Contract #: N00019-91-C-0191 Phone: (415) 941-7260 pl: Patricia W~cner Title: New Packaging...track processor could be held very small. IRVINE TECHNOLOGY GROUP, INC. Topic#: 89-146 ID#: 33161 9 St Maxime Office WL Laguna Niguel, CA 92677...Olfice. WL/EGLIN Laguna Hills. CA 92663 Contract #: F08635-91-C-0201 Phone- (205) 837-5200 Pl: DR OWEN C HOFER Title: Munition Neutralization Laser

  4. The impact of rate of weight loss on body composition and compensatory mechanisms during weight reduction

    DEFF Research Database (Denmark)

    Coutinho, Sílvia Ribeiro; With, Emilie; Rehfeld, Jens F

    2018-01-01

    BACKGROUND & AIMS: Rapid weight loss (WL) has been associated with a larger loss of fat free mass and a disproportional reduction in resting metabolic rate (RMR), but the evidence is inconclusive. We aimed to evaluate the impact of WL rate on body composition and compensatory mechanisms activated...... with WL (reduced RMR, increased exercise efficiency (ExEff) and appetite), both during negative and neutral energy balance (EB). METHODS: Thirty-five participants with obesity were randomized to lose a similar weight rapidly (4 weeks) or gradually (8 weeks), and afterwards to maintain it (4 weeks). Body...... weight and composition, RMR, ExEff (10, 25 and 50 W), appetite feelings and appetite-regulating hormones (active ghrelin, cholecystokinin, total peptide YY (PYY), active glucagon-like peptide-1 and insulin), in fasting and every 30 min up to 2.5 h, were measured at baseline and after each phase. RESULTS...

  5. Effects of rye bread enriched with green tea extract on weight maintenance and the characteristics of metabolic syndrome following weight loss: a pilot study.

    Science.gov (United States)

    Bajerska, Joanna; Mildner-Szkudlarz, Sylwia; Walkowiak, Jarosław

    2015-06-01

    We examined whether the incorporation of green tea extract enriched rye bread (GTRB) into the diet can improve weight loss (WL) maintenance and control of abnormalities linked to metabolic syndrome (MS). A total of 55 obese men and women (mean age: 53.0±7.0 years, body mass index: 35.0±5.5 kg m(-2)) were recruited. The study had a single-blind randomized study design and consisted of an 8-week WL phase with low-energy calorie diet, followed by a 12-week weight maintenance (WM) phase. During the WM phase, the subjects were randomized into two groups, receiving either the control rye bread (control group) or the GTRB (intervention group). The ingestion of 280 and 360 g GTRB provided daily totals of 123.2 and 158.4 mg caffeine, and 188.3 and 242.1 mg of epigallocatechin gallate, for women and men, respectively. After the WL phase, subjects lost 7.3±3.1 kg of their baseline body weight. GTRB intake did not significantly influence the maintenance of WL, high-density lipoprotein-cholesterol, triglycerides, and glucose concentrations. Although, it resulted in significant differences (mean difference [95% confidence interval]) between the treatment groups in the maintenance of waist circumference (-1.22 cm [-2.4, -0.02; P=.04]), the results were not clinically meaningful. Nevertheless, the ingestion of GTRB led to the maintenance of lower blood pressure (BP), also the proportion of subjects fulfilling the criteria of MS after the WM phase was lower in the intervention group than in the control group. Although GTRB consumption did not improve significantly the WL maintenance, it resulted in a better control of BP.

  6. The outcome of surgical resection versus assignment to the liver transplant waiting list for hepatocellular carcinoma.

    Science.gov (United States)

    Pierie, Jean-Pierre E N; Muzikansky, Alona; Tanabe, Kenneth K; Ott, Mark J

    2005-07-01

    Optimal management of patients with hepatocellular carcinoma (HCC) is controversial. This study was conducted to evaluate the outcome of tumor resection versus assignment to a liver transplant waiting list (WL) in patients with HCC. Prospectively collected patient data from 1970 to 1997 on 313 patients with HCC were retrospectively analyzed by multivariate analysis to determine the effect of liver disease, method of treatment, and tumor-related factors on survival. A total of 199 patients underwent nonsurgical palliative care (PC), 81 underwent partial liver resection (LR), and 33 were assigned to a liver transplant WL, of which 22 received a donor liver. A total of 91%, 53%, and 91% of the patients had cirrhotic livers in the PC, LR, and WL groups, respectively (P < .001). In the LR group, the absence of a tumor capsule (P < .0001) and a poorly differentiated tumor (P = .027) were both adverse prognostic factors. In the WL group, hepatitis B (P = .02) and American Joint Committee on Cancer tumor stage III (P = .019) were adverse prognostic factors. The 3-year survival rates were 4%, 33%, and 38% for the PC, LR, and WL patients, respectively (P < .0001). The 3-year survival rate in the LR patients was 51% in patients without cirrhosis and 15% in patients with cirrhosis (P < .0001). Patients with locally unresectable tumors, distant disease, or both will continue to receive PC. Patients assigned to liver transplant WLs run the risk of not receiving a donor liver, in which case their survival is predicted to be poor. Survival after resection in a group of patients with advanced tumors is worse than that after transplantation; however, shortages of donor livers presently preclude transplantation in this population of patients.

  7. ON THE ACCURACY OF WEAK-LENSING CLUSTER MASS RECONSTRUCTIONS

    International Nuclear Information System (INIS)

    Becker, Matthew R.; Kravtsov, Andrey V.

    2011-01-01

    We study the bias and scatter in mass measurements of galaxy clusters resulting from fitting a spherically symmetric Navarro, Frenk, and White model to the reduced tangential shear profile measured in weak-lensing (WL) observations. The reduced shear profiles are generated for ∼10 4 cluster-sized halos formed in a ΛCDM cosmological N-body simulation of a 1 h -1 Gpc box. In agreement with previous studies, we find that the scatter in the WL masses derived using this fitting method has irreducible contributions from the triaxial shapes of cluster-sized halos and uncorrelated large-scale matter projections along the line of sight. Additionally, we find that correlated large-scale structure within several virial radii of clusters contributes a smaller, but nevertheless significant, amount to the scatter. The intrinsic scatter due to these physical sources is ∼20% for massive clusters and can be as high as ∼30% for group-sized systems. For current, ground-based observations, however, the total scatter should be dominated by shape noise from the background galaxies used to measure the shear. Importantly, we find that WL mass measurements can have a small, ∼5%-10%, but non-negligible amount of bias. Given that WL measurements of cluster masses are a powerful way to calibrate cluster mass-observable relations for precision cosmological constraints, we strongly emphasize that a robust calibration of the bias requires detailed simulations that include more observational effects than we consider here. Such a calibration exercise needs to be carried out for each specific WL mass estimation method, as the details of the method determine in part the expected scatter and bias. We present an iterative method for estimating mass M 500c that can eliminate the bias for analyses of ground-based data.

  8. SU-F-J-53: A 3D Printed Phantom for the Use of Daily Quality Assurance Alignment Tests

    Energy Technology Data Exchange (ETDEWEB)

    Woods, K; Ayan, A; Woollard, J; Gardner, N; Gupta, N [Ohio State University Columbus, OH (United States)

    2016-06-15

    Purpose: To discuss experiences and results for a 3D printed QA phantom used for daily alignment purposes for a six degrees-of-freedom (6DoF) table Methods: A 3D model was created using a fused deposition modeling (FDM) printer using free online computer-aided design (CAD) software. The model has been under use for daily QA alignment tests for a 6DoF couch. An aligned and angled baseplate were also printed in order to introduce known angles for 6DoF corrections during image-guidance. Unique registration contours were created on the faces of the phantom in order to achieve a better cone-beam computed tomography (CBCT) match using an auto-registration algorithm. A BB was also introduced at the center of the phantom in order to deliver an integrated daily Winston-Lutz (WL) test. Translational, rotational, and WL results were tabulated over one month. Results: The ’honeycomb’ structure of the print was apparent in the EPID images for the WL test, which affected the results of the analysis software. This was fixed by inserting a cube made of polyoxymethylene within the 3D phantom that encompass the BB. Auto-registration results for the three translational and three rotational from a known offset to the BB isocenter consistently fell within 1 mm and 0.2°, respectively. WL tests resulted in an average of 0.71 ± 0.14 mm. Conclusion: 3D printed models allow for accurate builds that can be customized to a variety of clinical needs. Results from translational, rotational, and WL show consistent results over a month’s time. Given its relatively cheap and streamlined workflow, 3D printing could be implemented into any clinic looking to create customized phantoms.

  9. SU-F-J-53: A 3D Printed Phantom for the Use of Daily Quality Assurance Alignment Tests

    International Nuclear Information System (INIS)

    Woods, K; Ayan, A; Woollard, J; Gardner, N; Gupta, N

    2016-01-01

    Purpose: To discuss experiences and results for a 3D printed QA phantom used for daily alignment purposes for a six degrees-of-freedom (6DoF) table Methods: A 3D model was created using a fused deposition modeling (FDM) printer using free online computer-aided design (CAD) software. The model has been under use for daily QA alignment tests for a 6DoF couch. An aligned and angled baseplate were also printed in order to introduce known angles for 6DoF corrections during image-guidance. Unique registration contours were created on the faces of the phantom in order to achieve a better cone-beam computed tomography (CBCT) match using an auto-registration algorithm. A BB was also introduced at the center of the phantom in order to deliver an integrated daily Winston-Lutz (WL) test. Translational, rotational, and WL results were tabulated over one month. Results: The ’honeycomb’ structure of the print was apparent in the EPID images for the WL test, which affected the results of the analysis software. This was fixed by inserting a cube made of polyoxymethylene within the 3D phantom that encompass the BB. Auto-registration results for the three translational and three rotational from a known offset to the BB isocenter consistently fell within 1 mm and 0.2°, respectively. WL tests resulted in an average of 0.71 ± 0.14 mm. Conclusion: 3D printed models allow for accurate builds that can be customized to a variety of clinical needs. Results from translational, rotational, and WL show consistent results over a month’s time. Given its relatively cheap and streamlined workflow, 3D printing could be implemented into any clinic looking to create customized phantoms.

  10. The body project 4 all: A pilot randomized controlled trial of a mixed-gender dissonance-based body image program.

    Science.gov (United States)

    Kilpela, Lisa Smith; Blomquist, Kerstin; Verzijl, Christina; Wilfred, Salomé; Beyl, Robbie; Becker, Carolyn Black

    2016-06-01

    The Body Project is a cognitive dissonance-based body image improvement program with ample research support among female samples. More recently, researchers have highlighted the extent of male body dissatisfaction and disordered eating behaviors; however, boys/men have not been included in the majority of body image improvement programs. This study aims to explore the efficacy of a mixed-gender Body Project compared with the historically female-only body image intervention program. Participants included male and female college students (N = 185) across two sites. We randomly assigned women to a mixed-gender modification of the two-session, peer-led Body Project (MG), the two-session, peer-led, female-only (FO) Body Project, or a waitlist control (WL), and men to either MG or WL. Participants completed self-report measures assessing negative affect, appearance-ideal internalization, body satisfaction, and eating disorder pathology at baseline, post-test, and at 2- and 6-month follow-up. Linear mixed effects modeling to estimate the change from baseline over time for each dependent variable across conditions were used. For women, results were mixed regarding post-intervention improvement compared with WL, and were largely non-significant compared with WL at 6-month follow-up. Alternatively, results indicated that men in MG consistently improved compared with WL through 6-month follow-up on all measures except negative affect and appearance-ideal internalization. Results differed markedly between female and male samples, and were more promising for men than for women. Various explanations are provided, and further research is warranted prior to drawing firm conclusions regarding mixed-gender programming of the Body Project. © 2016 Wiley Periodicals, Inc.(Int J Eat Disord 2016; 49:591-602). © 2016 Wiley Periodicals, Inc.

  11. A randomised controlled pilot study: the effectiveness of narrative exposure therapy with adult survivors of the Sichuan earthquake

    Directory of Open Access Journals (Sweden)

    Zang Yinyin

    2013-01-01

    Full Text Available Abstract Background Post-Traumatic Stress Disorder (PTSD is a common psychological reaction after large-scale natural disasters. Given the number of people involved and shortage of resources in any major disaster, brief, pragmatic and easily trainable interventions are needed. The aim of this study is to evaluate the efficacy of Narrative Exposure Therapy (NET as a short-term treatment for PTSD using Chinese earthquake survivors. Methods A randomized waiting-list control pilot study was conducted between December 2009 and March 2010, at the site of the Sichuan earthquake in Beichuan County, China. Adult participants with newly diagnosed Post Traumatic Stress Disorder (PTSD were randomly allocated to Narrative Exposure Therapy (NET or a Waiting-List (WL condition. The latter received NET treatment after a two-week waiting period. To compare the effectiveness of NET in traumatised earthquake survivors, both groups were assessed on PTSD symptoms, general mental health, anxiety and depression, social support, coping style and posttraumatic change before and after treatment and two months post treatment. Results Adult participants (n=22 were randomly allocated to receive NET (n=11 or WL (n=11. Twenty two participants (11 in NET group, 11 in WL were included in the analysis of primary outcomes. Compared with WL, NET showed significant reductions in PTSD symptoms, anxiety and depression, general mental stress and increased posttraumatic growth. The WL group later showed similar improvements after treatment. These changes remained stable for a two-month follow-up. Measures of social support and coping showed no stable effects. Conclusions NET is effective in treating post-earthquake traumatic symptoms in adult Chinese earthquake survivors. The findings help advance current knowledge in the management of PTSD after natural disasters and inform future research. Larger sample sizes are needed to extend the present findings. Trial registration Chinese

  12. Comparing the Effectiveness of a Short-Term Vertical Jump vs. Weightlifting Program on Athletic Power Development.

    Science.gov (United States)

    Teo, Shaun Y M; Newton, Michael J; Newton, Robert U; Dempsey, Alasdair R; Fairchild, Timothy J

    2016-10-01

    Teo, SYM, Newton, MJ, Newton, RU, Dempsey, AR, and Fairchild, TJ. Comparing the effectiveness of a short-term vertical jump vs. weightlifting program on athletic power development. J Strength Cond Res 30(10): 2741-2748, 2016-Efficient training of neuromuscular power and the translation of this power to sport-specific tasks is a key objective in the preparation of athletes involved in team-based sports. The purpose of this study was to compare changes in center of mass (COM) neuromuscular power and performance of sport-specific tasks after short-term (6-week) training adopting either Olympic-style weightlifting (WL) exercises or vertical jump (VJ) exercises. Twenty-six recreationally active men (18-30 years; height: 178.7 ± 8.3 cm; mass: 78.6 ± 12.2 kg) were randomly allocated to either a WL or VJ training group and performance during the countermovement jump (CMJ), squat jump (SJ), depth jump (DJ), 20-m sprint, and the 5-0-5 agility test-assessed pre and posttraining. Despite the WL group demonstrating larger increases in peak power output during the CMJ (WL group: 10% increase, d = 0.701; VJ group: 5.78% increase, d = 0.328) and SJ (WL group: 12.73% increase, d = 0.854; VJ group: 7.27% increase, d = 0.382), no significant between-group differences were observed in any outcome measure studied. There was a significant main effect of time observed for the 3 VJs (CMJ, SJ, and DJ), 0- to 5-m and 0- to 20-m sprint times, and the 5-0-5 agility test time, which were all shown to improve after the training (all main effects of time p sports, even in athletes with limited preseason training periods.

  13. Femoral rotational asymmetry is a common anatomical variant.

    Science.gov (United States)

    Newman, Christopher R; Walter, William L; Talbot, Simon

    2018-05-01

    The sulcus line (SL) is a three-dimensional landmark that corrects for individual variation in the coronal alignment of the trochlear groove in contrast to the traditional Whiteside's line (WL). Femoral rotational asymmetry (FRA) is an anatomical variation in which the posterior condyles and trochlear groove are not perpendicular to each other. This study aims to measure the SL and assess its reliability relative to WL, in addition to measuring and classifying the FRA. A retrospective analysis of a series of 191 CT scans of nonarthritic knees was performed. Measurements were taken of rotational landmarks in three-dimensional reconstructions. The variability and outlier rate of SL was less than WL (P  0.05), however it decreased the rate of change of the rotational alignment of the trochlear groove between the native knee and the prosthetic knee from 31% to 5% (P 5° in 56/191 (29%) of cases. The SL technique is more accurate than WL for determining the rotational alignment of the trochlear groove. Nonarthritic femora have a high rate of rotational asymmetry. Identifying and classifying FRA in individual cases allows the femoral component to be inserted in a position which gives the best possible match to both the native posterior condyles and trochlear groove. Clin. Anat. 31:551-559, 2018. © 2018 Wiley Periodicals, Inc. © 2018 Wiley Periodicals, Inc.

  14. Nonlinear optical rectification in a vertically coupled lens-shaped InAs/GaAs quantum dots with wetting layers under hydrostatic pressure and temperature

    Energy Technology Data Exchange (ETDEWEB)

    Ben Mahrsia, R.; Choubani, M., E-mail: mohsenchoubani3@yahoo.fr; Bouzaiene, L.; Maaref, H.

    2016-06-25

    In this paper we explore the structure parameters, hydrostatic pressure and temperature effects on Nonlinear optical rectification (NOR) in an asymmetric vertically coupled lens-shaped InAs/GaAs quantum dots. During epitaxial growth, lens-shaped quantum dots (QDs) are formed on the wetting layer (WL). Many theoretical works have neglected WL and its effect on nonlinear optical properties of QD-based systems for sake of simplicity. However, in this work the WL has been shown to be so influential in the intersubband energy and nonlinear optical rectification magnitude. Also, a detailed and comprehensive study of the nonlinear optical rectification is theoretical investigated within the framework of the compact density-matrix approach and finite difference method (FDM). It's found that nonlinear optical rectification coefficient is strongly affected not only by the WL, but also by the pressure, temperature and the coupled width between the QDs. Obtained results revealed that a red or a blue shift cane be observed. This behavior in the NOR gives a new degree of freedom in regions of interest for device applications. - Highlights: • Vertically coupled lens-shaped InAs/GaAs quantum dots is investigated. • Photon energy shifts towards the red with increasing pressure. • Photon energy shifts towards the blue with increasing temperature. • Intersubband energy decreases with increasing the wetting layer width. • Nonlinear optical rectification magnitude is controlled and adjusted.

  15. Light-stimulated cell expansion in bean (Phaseolus vulgaris L.) leaves. I. Growth can occur without photosynthesis

    Science.gov (United States)

    Van Volkenburgh, E.; Cleland, R. E.

    1990-01-01

    Cell expansion in dicotyledonous leaves is strongly stimulated by bright white light (WL), at least in part as a result of light-induced acidification of the cell walls. It has been proposed that photosynthetic reactions are required for light-stimulated transport processes across plasma membranes of leaf cells, including proton excretion. The involvement of photosynthesis in growth and wall acidification of primary leaves of bean has been tested by inhibiting photosynthesis in two ways: by reducing chlorophyll content of intact plants with tentoxin (TX) and by treating leaf discs with 3-(3,4-dichlorophenyl)-1,1-dimethylurea (DCMU). Exposure to bright WL stimulated growth of intact leaves of TX-treated plants. Discs excised from green as well as from TX-or DCMU-treated leaves also responded by growing faster in WL, as long as exogenous sucrose was supplied to the photosynthetically inhibited tissues. The WL caused acidification of the epidermal surface of intact TX-leaves, but acidification of the incubation medium by mesophyll cells only occurred when photosynthesis was not inhibited. It is concluded that light-stimulated cell enlargement of bean leaves, and the necessary acidification of epidermal cell walls, are mediated by a pigment other than chlorophyll. Light-induced proton excretion by mesophyll cells, on the other hand, may require both a photosynthetic product (or exogenous sugars) and a non-photosynthetic light effect.

  16. Development of X-Y multiwire proportional chamber (MWPC) for the magnetic spectrograph 'BIG KARL' of the Juelich cyclotron 'JULIC' and investigation of the reaction 12C(α,α1)12C with Eα=145 MeV

    International Nuclear Information System (INIS)

    Koehler, M.

    1978-07-01

    The paper reports on the concept and development of a spatial-resolution X-Y detector for the magnetic spectrograph BIG KARL, on test measurements on the 300 mm x 40 mm prototype with a 90 Sr β source, and on the first few in-beam measurements. The reaction 12 C(α,α') 12 C with Esub(α) = 145 MeV was investigated under extreme forward angles thetasub(LAB) = 6.0 0 to 1.5 0 . (orig./WL) 891 WL [de

  17. Use of a microprocessor in a remote working level monitor

    International Nuclear Information System (INIS)

    Keefe, D.J.; McDowell, W.P.; Groer, P.G.

    1976-01-01

    The instrument described measures the short-lived 222 Rn-daughter concentrations and the Working Level (WL) in sealed ''hot chambers'' located in uranium mines. Radiation-induced pulses from two separate sensors are transmitted through 500 ft. cables to a microprocessor, which processes the pulses and controls the operation of the system. A read-only memory stores a fixed program which is used to calculate the desired concentrations. The results are printed as pCi/l (Rn-daughter concentrations) and WL

  18. Workshop on ROVs and deep submergence

    Science.gov (United States)

    The deep-submergence community has an opportunity on March 6 to participate in a unique teleconferencing demonstration of a state-of-the-art, remotely operated underwater research vehicle known as the Jason-Medea System. Jason-Medea has been developed over the past decade by scientists, engineers, and technicians at the Deep Submergence Laboratory at Woods Hole Oceanographic Institution. The U.S. Navy, the Office of the Chief of Naval Research, and the National Science Foundation are sponsoring the workshop to explore the roles that modern computational, communications, and robotics technologies can play in deep-sea oceanographic research.Through the cooperation of Electronic Data Systems, Inc., the Jason Foundation, and Turner Broadcasting System, Inc., 2-1/2 hours of air time will be available from 3:00 to 5:30 PM EST on March 6. Twenty-seven satellite downlink sites will link one operating research vessel and the land-based operation with workshop participants in the United States, Canada, the United Kingdom, and Bermuda. The research ship Laney Chouest will be in the midst of a 3-week educational/research program in the Sea of Cortez, between Baja California and mainland Mexico. This effort is focused on active hydrothermal vents driven by heat flow from the volcanically active East Pacific Rise, which underlies the sediment-covered Guaymas Basin. The project combines into a single-operation, newly-developed robotic systems, state-of-the-art mapping and sampling tools, fiber-optic data transmission from the seafloor, instantaneous satellite communication from ship to shore, and a sophisticated array of computational and telecommunications networks. During the workshop, land-based scientists will observe and participate directly with their seagoing colleagues as they conduct seafloor research.

  19. Separation of acid blue 25 from aqueous solution using water lettuce and agro-wastes by batch adsorption studies

    Science.gov (United States)

    Kooh, Muhammad Raziq Rahimi; Dahri, Muhammad Khairud; Lim, Linda B. L.; Lim, Lee Hoon; Chan, Chin Mei

    2018-05-01

    Three plant-based materials, namely water lettuce (WL), tarap peel (TP) and cempedak peel (CP), were used to investigate their potentials as adsorbents using acid blue 25 (AB25) dye as a model for acidic dye. The adsorbents were characterised using Fourier transform infrared spectroscopy, X-ray fluorescence and scanning electron microscope. Batch experiments involving parameters such as pH, temperature, contact time, and initial dye concentration were done to investigate the optimal conditions for the adsorption of AB25 onto the adsorbents. Thermodynamics study showed that the uptake of AB25 by the three adsorbents was feasible and endothermic in nature. Both the Langmuir and Freundlich isotherm models can be used to describe the adsorption process of AB25 onto WL and CP while pseudo-second-order fitted the kinetics data, suggesting that chemisorptions were majorly involved. The use of 0.1 M of NaOH showed the best results in regenerating of the WL, TP and CP's adsorption ability after AB25 treatment.

  20. Timeline of changes in appetite during weight loss with a ketogenic diet

    DEFF Research Database (Denmark)

    Nymo, S; Coutinho, S R; Jørgensen, J

    2017-01-01

    BACKGROUND/OBJECTIVE: Diet-induced weight loss (WL) leads to increased hunger and reduced fullness feelings, increased ghrelin and reduced satiety peptides concentration (glucagon-like peptide-1 (GLP-1), cholecystokinin (CCK) and peptide YY (PYY)). Ketogenic diets seem to minimise or supress some...... of these responses. The aim of this study was to determine the timeline over which changes in appetite occur during progressive WL with a ketogenic very-low-energy diet (VLED). SUBJECTS/METHODS: Thirty-one sedentary adults (18 men), with obesity (body mass index: 37±4.5 kg m-2) underwent 8 weeks (wks) of a VLED...... followed by 4 wks of weight maintenance. Body weight and composition, subjective feelings of appetite and appetite-related hormones (insulin, active ghrelin (AG), active GLP-1, total PYY and CCK) were measured in fasting and postprandially, at baseline, on day 3 of the diet, 5 and 10% WL, and at wks 9...

  1. Projection Effects of Large-scale Structures on Weak-lensing Peak Abundances

    Science.gov (United States)

    Yuan, Shuo; Liu, Xiangkun; Pan, Chuzhong; Wang, Qiao; Fan, Zuhui

    2018-04-01

    High peaks in weak lensing (WL) maps originate dominantly from the lensing effects of single massive halos. Their abundance is therefore closely related to the halo mass function and thus a powerful cosmological probe. However, besides individual massive halos, large-scale structures (LSS) along lines of sight also contribute to the peak signals. In this paper, with ray-tracing simulations, we investigate the LSS projection effects. We show that for current surveys with a large shape noise, the stochastic LSS effects are subdominant. For future WL surveys with source galaxies having a median redshift z med ∼ 1 or higher, however, they are significant. For the cosmological constraints derived from observed WL high-peak counts, severe biases can occur if the LSS effects are not taken into account properly. We extend the model of Fan et al. by incorporating the LSS projection effects into the theoretical considerations. By comparing with simulation results, we demonstrate the good performance of the improved model and its applicability in cosmological studies.

  2. [Exclusive breastfeeding in <6mo is associated to a better weight for length in households with food insecurity in Mexico].

    Science.gov (United States)

    González-de Cossío, Teresita; Escobar-Zaragoza, Leticia; González-Castell, Dinorah; Shamah-Levy, Teresa; Rivera-Dommarco, Juan A

    2014-01-01

    To evaluate the effect of exclusive breastfeeding in ENSANUT 2012 (n = 4 022). Breastfeeding indicators from WHO-2008 were calculated. We estimated the effect modifier EBF<6mo of the relationship between FI and weight length (Z W/L) and length for age (Z L/A) Z score. The EBF<6mo was lower in households (hh) with moderate and severe FI than in those with food security (FS) or mild FI hh. Only EBF<6mo infants from hh with moderate and severe FI showed greater Z W/L (0.44) than those without EBF<6mo (p= 0.038, one-tailed). Score Z W/L of infants from hh FS did not vary according to EBF<6mo. EBF<6mo in Mexican infants is associated with better weight for length in households with moderate and severe FI. Breastfeeding promotion, protection and support must be targeted mainly at the most vulnerable, food insecure families.

  3. The lambda mechanism of the 0nbb-decay

    Science.gov (United States)

    Šimkovic, Fedor; Štefánik, Dušan; Dvornický, Rastislav

    2017-11-01

    The lambda mechanism (WL-WR exchange) of the neutrinoless double beta decay (0nbb-decay), which has origin in left-right symmetric model with right-handed gauge boson at TeV scale, is investigated. The revisited formalism of the 0nbb-decay, which includes higher order terms of nucleon current, is exploited. The corresponding nuclear matrix elements are calculated within quasiparticle random phase approximation with partial restoration of the isospin symmetry for nuclei of experimental interest. A possibility to distinguish between the conventional light neutrino mass (WL-WL exchange) and lambda mechanisms by observation of the 0nbb-decay in several nuclei is discussed. A qualitative comparison of effective lepton number violating couplings associated with these two mechanisms is performed. By making viable assumption about the seesaw type mixing of light and heavy neutrinos it is concluded that there is a dominance of the conventional light neutrino mass mechanism in the decay rate.

  4. Phonons of single quintuple Bi 2 Te 3 and Bi 2 Se 3 films and bulk materials

    KAUST Repository

    Cheng, Wei; Ren, Shang-Fen

    2011-01-01

    Phonons of single quintuple films of Bi2Te3 and Bi2Se3 and corresponding bulk materials are calculated in detail by MedeA (a trademark of Materials Design) and Vienna ab initio simulation package (VASP). The calculated results with and without spin-orbit couplings are compared, and the important roles that the spin-orbit coupling plays in these materials are discussed. A symmetry breaking caused by the anharmonic potentials around Bi atoms in the single quintuple films is identified and discussed. The observed Raman intensity features in Bi 2Te3 and Bi2Se3 quintuple films are explained. © 2011 American Physical Society.

  5. Phonons of single quintuple Bi 2 Te 3 and Bi 2 Se 3 films and bulk materials

    KAUST Repository

    Cheng, Wei

    2011-03-10

    Phonons of single quintuple films of Bi2Te3 and Bi2Se3 and corresponding bulk materials are calculated in detail by MedeA (a trademark of Materials Design) and Vienna ab initio simulation package (VASP). The calculated results with and without spin-orbit couplings are compared, and the important roles that the spin-orbit coupling plays in these materials are discussed. A symmetry breaking caused by the anharmonic potentials around Bi atoms in the single quintuple films is identified and discussed. The observed Raman intensity features in Bi 2Te3 and Bi2Se3 quintuple films are explained. © 2011 American Physical Society.

  6. Reliability Assessment of Concrete Bridges

    DEFF Research Database (Denmark)

    Thoft-Christensen, Palle; Middleton, C. R.

    This paper is partly based on research performed for the Highways Agency, London, UK under the project DPU/9/44 "Revision of Bridge Assessment Rules Based on Whole Life Performance: concrete bridges". It contains the details of a methodology which can be used to generate Whole Life (WL) reliability...... profiles. These WL reliability profiles may be used to establish revised rules for concrete bridges. This paper is to some extend based on Thoft-Christensen et. al. [1996], Thoft-Christensen [1996] et. al. and Thoft-Christensen [1996]....

  7. Blood lead levels and bone turnover with weight reduction in women

    OpenAIRE

    RIEDT, CLAUDIA S.; BUCKLEY, BRIAN T.; BROLIN, ROBERT E.; AMBIA-SOBHAN, HASINA; RHOADS, GEORGE G.; SHAPSES, SUE A.

    2008-01-01

    High bone turnover states are known to raise blood lead levels (BPb). Caloric restriction will increase bone turnover, yet it remains unknown if weight reduction increases BPb due to mobilization of skeletal stores. We measured whole blood Pb levels (206Pb) by inductively coupled plasma mass spectrometry in 73 women (age 24–75 years; BMI 23– 61 kg/m2) before and after 6 months of severe weight loss (S-WL), moderate weight loss (M-WL), or weight maintenance (WM). Baseline BPb levels were relat...

  8. High-Protein Intake during Weight Loss Therapy Eliminates the Weight-Loss-Induced Improvement in Insulin Action in Obese Postmenopausal Women

    OpenAIRE

    Gordon I. Smith; Jun Yoshino; Shannon C. Kelly; Dominic N. Reeds; Adewole Okunade; Bruce W. Patterson; Samuel Klein; Bettina Mittendorfer

    2016-01-01

    High-protein (HP) intake during weight loss (WL) therapy is often recommended because it reduces the loss of lean tissue mass. However, HP intake could have adverse effects on metabolic function, because protein ingestion reduces postprandial insulin sensitivity. In this study, we compared the effects of ∼10% WL with a hypocaloric diet containing 0.8 g protein/kg/day and a hypocaloric diet containing 1.2 g protein/kg/day on muscle insulin action in postmenopausal women with obesity. We found ...

  9. Thermal characterization of organic matter along a (hypothetical) coalification gradient

    Science.gov (United States)

    Cavallo, Ornella; Provenzano, Maria Rosaria; Zaccone, Claudio

    2017-04-01

    Geochemical transformations of organic carbon (C) in aquatic and terrestrial ecosystems are important starting points for genesis of peats, brown coals and other coal precursors. The humification process plays a key role in biogeochemical transformations of organic C and, as a result, in the first stages of coal precursors formation. Thermal analysis was used by Schnitzer and other scientists since 1950-1960s, in order to investigate the stability of several organic materials of industrial value including peat and coal. What soil scientists found was the general occurrence of two exothermic peaks (exotherm 1 and 2) due to decomposition and combustion reactions of organic compounds having different thermal stability and, consequently, different degree of humification. Thermogravimetric analysis (TG) was carried out on different samples reproducing a "hypothetical" coalification gradient as follows: peat (IHSS Pahokee peat standard), fulvic acid (FA), a peat humic acid (HA), leonardite (IHSS Gascoyne standard) and charcoal. An aliquot of about 20 mg of each sample was heated in a ceramic crucible from 50 to 850˚ C at 30˚ C min-1, at a gas flow rate of 30 mL min-1 using a PerkinElmer TGA4000 thermobalance. Samples were analysed both under nitrogen and under synthetic air. All analyses were carried out in triplicate and the average coefficient of variation was bio-transformation of organic materials. Finally, the temperature at which half of the exothermic mass loss has occurred (TG-T50) was also calculated. Preliminary results obtained from TG analysis under air showed that WL2/WL1 ratio was lower for the FA sample and higher for leonardite and charcoal, following the order FAWL2/WL1 ratio (HFWL

  10. Integrated mRNA and microRNA analysis identifies genes and small miRNA molecules associated with transcriptional and post-transcriptional-level responses to both drought stress and re-watering treatment in tobacco.

    Science.gov (United States)

    Chen, Qiansi; Li, Meng; Zhang, Zhongchun; Tie, Weiwei; Chen, Xia; Jin, Lifeng; Zhai, Niu; Zheng, Qingxia; Zhang, Jianfeng; Wang, Ran; Xu, Guoyun; Zhang, Hui; Liu, Pingping; Zhou, Huina

    2017-01-10

    Drought stress is one of the most severe problem limited agricultural productivity worldwide. It has been reported that plants response to drought-stress by sophisticated mechanisms at both transcriptional and post-transcriptional levels. However, the precise molecular mechanisms governing the responses of tobacco leaves to drought stress and water status are not well understood. To identify genes and miRNAs involved in drought-stress responses in tobacco, we performed both mRNA and small RNA sequencing on tobacco leaf samples from the following three treatments: untreated-control (CL), drought stress (DL), and re-watering (WL). In total, we identified 798 differentially expressed genes (DEGs) between the DL and CL (DL vs. CL) treatments and identified 571 DEGs between the WL and DL (WL vs. DL) treatments. Further analysis revealed 443 overlapping DEGs between the DL vs. CL and WL vs. DL comparisons, and, strikingly, all of these genes exhibited opposing expression trends between these two comparisons, strongly suggesting that these overlapping DEGs are somehow involved in the responses of tobacco leaves to drought stress. Functional annotation analysis showed significant up-regulation of genes annotated to be involved in responses to stimulus and stress, (e.g., late embryogenesis abundant proteins and heat-shock proteins) antioxidant defense (e.g., peroxidases and glutathione S-transferases), down regulation of genes related to the cell cycle pathway, and photosynthesis processes. We also found 69 and 56 transcription factors (TFs) among the DEGs in, respectively, the DL vs. CL and the WL vs. DL comparisons. In addition, small RNA sequencing revealed 63 known microRNAs (miRNA) from 32 families and 368 novel miRNA candidates in tobacco. We also found that five known miRNA families (miR398, miR390, miR162, miR166, and miR168) showed differential regulation under drought conditions. Analysis to identify negative correlations between the differentially expressed mi

  11. Genomewide analysis indicates that queen larvae have lower methylation levels in the honey bee ( Apis mellifera)

    Science.gov (United States)

    Shi, Yuan Yuan; Yan, Wei Yu; Huang, Zachary Y.; Wang, Zi Long; Wu, Xiao Bo; Zeng, Zhi Jiang

    2013-02-01

    The honey bee is a social insect characterized by caste differentiation, by which a young larva can develop into either a queen or a worker. Despite possessing the same genome, queen and workers display marked differences in reproductive capacity, physiology, and behavior. Recent studies have shown that DNA methylation plays important roles in caste differentiation. To further explore the roles of DNA methylation in this process, we analyzed DNA methylome profiles of both queen larvae (QL) and worker larvae (WL) of different ages (2, 4, and 6 day old), by using methylated DNA immunoprecipitation-sequencing (meDIP-seq) technique. The global DNA methylation levels varied between the larvae of two castes. DNA methylation increased from 2-day- to 4-day-old QL and then decreased in 6-day-old larvae. In WL, methylation levels increased with age. The methylcytosines in both larvae were enriched in introns, followed by coding sequence (CDS) regions, CpG islands, 2 kbp downstream and upstream of genes, and 5' and 3' untranslated regions (UTRs). The number of differentially methylated genes (DMGs) in 2-, 4-, and 6-day-old QL and WL was 725, 3,013, and 5,049, respectively. Compared to 4- and 6-day-old WL, a large number of genes in QL were downmethylated, which were involved in many processes including development, reproduction, and metabolic regulation. In addition, some DMGs were concerned with caste differentiation.

  12. Spatial Distribution of Biomass and Woody Litter for Bio-Energy in Biscay (Spain

    Directory of Open Access Journals (Sweden)

    Esperanza Mateos

    2018-05-01

    Full Text Available Forest management has been considered a subject of interest, because they act as carbon (C sinks to mitigate CO 2 emissions and also as producers of woody litter (WL for bio-energy. Overall, a sustainably managed system of forests and forest products contributes to carbon mitigation in a positive, stable way. With increasing demand for sustainable production, the need to effectively utilise site-based resources increases. The utilization of WL for bio-energy can help meet the need for renewable energy production. The objective of the present study was to investigate biomass production (including C sequestration from the most representative forestry species (Pinus radiata D. Don and Ecualyptus globulus Labill of Biscay (Spain. Data from the third and fourth Spanish Forest Inventories (NFI3-2005 and NFI4-2011 were used. We also estimated the potential WL produced in the forest activities. Our findings were as follows: Forests of Biscay stored 12.084 Tg of biomass (dry basis, with a mean of 147.34 Mg ha - 1 in 2005 and 14.509 Tg of biomass (dry basis, with a mean of 179.82 Mg ha - 1 in 2011. The total equivalent CO 2 in Biscay’s forests increased by 1.629 Tg year - 1 between 2005 and 2011. The study shows that the energy potential of carbon accumulated in the WL amounted to 1283.2 million MJ year - 1 . These results suggest a considerable potential for energy production.

  13. Flash Flood Prediction by Coupling KINEROS2 and HEC-RAS Models for Tropical Regions of Northern Vietnam

    Directory of Open Access Journals (Sweden)

    Hong Quang Nguyen

    2015-11-01

    Full Text Available Northern Vietnam is a region prone to heavy flash flooding events. These often have devastating effects on the environment, cause economic damage and, in the worst case scenario, cost human lives. As their frequency and severity are likely to increase in the future, procedures have to be established to cope with this threat. As the prediction of potential flash floods represents one crucial element in this circumstance, we will present an approach that combines the two models KINEROS2 and HEC-RAS in order to accurately predict their occurrence. We used a documented event on 23 June 2011 in the Nam Khat and the larger adjacent Nam Kim watershed to calibrate the coupled model approach. Afterward, we evaluated the performance of the coupled models in predicting flow velocity (FV, water levels (WL, discharge (Q and streamflow power (P during the 3–5 days following the event, using two different precipitation datasets from the global spectral model (GSM and the high resolution model (HRM. Our results show that the estimated Q and WL closely matched observed data with a Nash–Sutcliffe simulation efficiency coefficient (NSE of around 0.93 and a coefficient of determination (R2 at above 0.96. The resulting analyses reveal strong relationships between river geometry and FV, WL and P. Although there were some minor errors in forecast results, the model-predicted Q and WL corresponded well to the gauged data.

  14. LoCuSS: THE SUNYAEV–ZEL'DOVICH EFFECT AND WEAK-LENSING MASS SCALING RELATION

    International Nuclear Information System (INIS)

    Marrone, Daniel P.; Carlstrom, John E.; Gralla, Megan; Greer, Christopher H.; Hennessy, Ryan; Leitch, Erik M.; Plagge, Thomas; Smith, Graham P.; Okabe, Nobuhiro; Bonamente, Massimiliano; Hasler, Nicole; Culverhouse, Thomas L.; Hawkins, David; Lamb, James W.; Muchovej, Stephen; Joy, Marshall; Martino, Rossella; Mazzotta, Pasquale; Miller, Amber; Mroczkowski, Tony

    2012-01-01

    We present the first weak-lensing-based scaling relation between galaxy cluster mass, M WL , and integrated Compton parameter Y sph . Observations of 18 galaxy clusters at z ≅ 0.2 were obtained with the Subaru 8.2 m telescope and the Sunyaev-Zel'dovich Array. The M WL -Y sph scaling relations, measured at Δ = 500, 1000, and 2500 ρ c , are consistent in slope and normalization with previous results derived under the assumption of hydrostatic equilibrium (HSE). We find an intrinsic scatter in M WL at fixed Y sph of 20%, larger than both previous measurements of M HSE -Y sph scatter as well as the scatter in true mass at fixed Y sph found in simulations. Moreover, the scatter in our lensing-based scaling relations is morphology dependent, with 30%-40% larger M WL for undisturbed compared to disturbed clusters at the same Y sph at r 500 . Further examination suggests that the segregation may be explained by the inability of our spherical lens models to faithfully describe the three-dimensional structure of the clusters, in particular, the structure along the line of sight. We find that the ellipticity of the brightest cluster galaxy, a proxy for halo orientation, correlates well with the offset in mass from the mean scaling relation, which supports this picture. This provides empirical evidence that line-of-sight projection effects are an important systematic uncertainty in lensing-based scaling relations.

  15. Discrimination of wild-growing and cultivated Lentinus edodes by tri-step infrared spectroscopy

    Science.gov (United States)

    Lin, Haojian; Liu, Gang; Yang, Weimei; An, Ran; Ou, Quanhong

    2018-01-01

    It's not easy to discriminate dried wild-growing Lentinus edodes (WL) and cultivated Lentinus edodes (CL) by conventional method based on the morphological inspection of fruiting bodies. In this paper, fruiting body samples of WL and CL are discriminated by a tri-step IR spectroscopy method, including Fourier transform infrared (FT-IR) spectroscopy, second derivatives infrared (SD-IR) spectroscopy and two-dimensional correlation infrared (2D-IR) spectroscopy under thermal perturbation. The results show that the FT-IR spectra of WL and CL are similar in holistic spectral profile. More significant differences are exhibited in their SD-IR spectra in the range of 1700 - 900 cm-1. Furthermore, more evident differences have been observed in their synchronous 2D-IR spectra in the range of 2970 - 2900, 1678 - 1390, 1250 -1104 and 1090 - 1030 cm-1. The CL has thirteen auto-peaks at 2958, 2921, 1649, 1563, 1450, 1218, 1192, 1161, 1140, 1110, 1082, 1065 and 1047 cm-1, in which the four strongest auto-peaks are at 2921, 1563, 1192 and 1082 cm-1. The WL shows fifteen auto-peaks at 2960, 2937, 2921, 1650, 1615, 1555, 1458, 1219, 1190, 1138, 1111, 1084, 1068, 1048 and 1033 cm-1, in which the four strongest auto-peaks are at 2921, 1650, 1190 and 1068 cm-1. This study shows the potential of FT-IR spectroscopy and 2D correlation analysis in a simple and quick distinction of wild-growing and cultivated mushrooms.

  16. Radiation-tolerant cable management systems for remote handling applications in the nuclear industry

    International Nuclear Information System (INIS)

    Cullen, S.; Thom, M.

    1993-01-01

    Experience has shown that one of the most vulnerable areas within remote handling equipment is the umbilical cable and termination system. Repairs of a damaged system can be very long due to poorly designed termination techniques. Over the past five years W.L. Gore has gained considerable experience in the design and manufacture of cable systems, utilising unique radiation tolerant materials and manufacturing processes. The cable systems manufactured at the W.L. Gore, Dunfermline, Scotland facility have proven to give excellent performance in the most demanding of remote handling applications. (author)

  17. Temperature-dependent evolution of the wetting layer thickness during Ge deposition on Si(001).

    Science.gov (United States)

    Bergamaschini, R; Brehm, M; Grydlik, M; Fromherz, T; Bauer, G; Montalenti, F

    2011-07-15

    The evolution of the wetting layer (WL) thickness during Ge deposition on Si(001) is analyzed with the help of a rate-equation approach. The combined role of thickness, island volume and shape-dependent chemical potentials is considered. Several experimental observations, such as WL thinning following the pyramid-to-dome transformation, are captured by the model, as directly demonstrated by a close comparison with photoluminescence measurements (PL) on samples grown at three different temperatures. The limitations of the model in describing late stages of growth are critically addressed.

  18. Community question.

    Science.gov (United States)

    McCrae, Niall; Spence, Cameron

    2015-10-01

    THE BED manager scanned the whiteboard in the busy office of an acute psychiatric ward. 'What about this man, WL?' she asked. 'He's been in for nearly two weeks. Can he go on weekend leave?' The nurse in charge was sceptical, but an urgent admission was imminent, and there was no room. So WL was informed that he was ready for a trial period at home, and his bed was swiftly changed for the new arrival. Such is life in the inner-city psychiatric ward, where demand relentlessly exceeds supply.

  19. Quality of working life of nurses in a tertiary cancer center in Qatar

    Directory of Open Access Journals (Sweden)

    Santhirani Nagammal

    2017-01-01

    Full Text Available Background Nurses are the largest segment of professionals working in the healthcare industry, and a satisfactory quality of working life will empower them to provide the highest quality care to their patients. Aim To assess the quality of working life among nurses in a tertiary cancer care center in Qatar concerning the following variables; control at work, employee engagement, general well-being, home-work interface, job/career satisfaction, stress at work, and working conditions. Methods A cross-sectional, descriptive study was conducted to assess the QoWL among 146 Staff Nurses working in different units of a tertiary cancer center in Qatar. A Quality of Work life Scale, a seven-point Likert’s scale was used, were nurses self-reported their QoWL. Results The mean age of the study participants were 36.48 years ± 6.74, and mean total years of clinical experience in nursing and clinical experience at the center was 14.16 years and 7.65 years respectively. The majority (69.9% of the nurses who participated in the study were working in inpatient units. Around fifty-four percentage were graduate nurses. A vast majority (89.7% of the respondents were married and among them, 84.2% of nurses lived with their family. Nurses’ perception of the factors associated with QoWL including control and stress at work were found average, and others such as employee engagement, general well-being, homework interface, job/career satisfaction, working condition, and overall quality of work life were considered good. There was no statistically significant difference in the QoWL scores and participants’ characteristics (P>0.05. Conclusion The overall QoWL was found to be good for the Oncology Nurses working at a cancer center in Qatar. However, Nurses reported having varying degrees of stress at work. Nurses require highly specialized clinical competencies to accurately determine patients' states and predict and cope with difficulties that may occur during

  20. Counterbalancing risks and gains from extended resections in malignant glioma surgery: a supplemental analysis from the randomized 5-aminolevulinic acid glioma resection study. Clinical article.

    Science.gov (United States)

    Stummer, Walter; Tonn, Jörg-Christian; Mehdorn, Hubertus Maximilian; Nestler, Ulf; Franz, Kea; Goetz, Claudia; Bink, Andrea; Pichlmeier, Uwe

    2011-03-01

    Accumulating data suggest more aggressive surgery in patients with malignant glioma to improve outcome. However, extended surgery may increase morbidity. The randomized Phase III 5-aminolevulinic acid (ALA) study investigated 5-ALA-induced fluorescence as a tool for improving resections. An interim analysis demonstrated more frequent complete resections with longer progression-free survival (PFS). However, marginal differences were found regarding neurological deterioration and the frequency of additional therapies. Presently, the authors focus on the latter aspects in the final study population, and attempt to determine how safety might be affected by cytoreductive surgery. Patients with malignant gliomas were randomized for fluorescence-guided (ALA group) or conventional white light (WL) (WL group) microsurgery. The final intent-to-treat population consisted of 176 patients in the ALA and 173 in the WL group. Primary efficacy variables were contrast-enhancing tumor on early MR imaging and 6-month PFS. Among secondary outcome measures, the National Institutes of Health Stroke Scale (NIH-SS) score and the Karnofsky Performance Scale (KPS) score were used for assessing neurological function. More frequent complete resections and improved PFS were confirmed, with higher median residual tumor volumes in the WL group (0.5 vs 0 cm(3), p = 0.001). Patients in the ALA group had more frequent deterioration on the NIH-SS at 48 hours. Patients at risk were those with deficits unresponsive to steroids. No differences were found in the KPS score. Regarding outcome, a combined end point of risks and neurological deficits was attempted, which demonstrated results in patients in the ALA group to be superior to those in participants in the WL group. Interestingly, the cumulative incidence of repeat surgery was significantly reduced in ALA patients. When stratified by completeness of resection, patients with incomplete resections were quicker to deteriorate neurologically (p = 0

  1. Intragastric Balloon for Obesity Treatment: Safety, Tolerance, and Efficacy

    Directory of Open Access Journals (Sweden)

    Joana Ribeiro da Silva

    2017-12-01

    Full Text Available Background: Obesity is an increasing worldwide problem associated with a vast number of comorbidities. Decreasing body weight by only 5-10% has been shown to slow and even prevent the onset of obesity-related comorbidities. Between pharmacological therapy and bariatric surgery a great variety of endoscopic techniques are available, the most common being intragastric balloon (IGB. The purpose of this study was to assess the safety, tolerance, and kinetics of IGBs in weight loss. The kinetics of weight loss were evaluated in 2 different contexts and phases: after the IGB's removal and after follow-up that varied between 6 and 12 months. Successful weight loss was defined as ≥10% weight loss after 6-12 months. Methods: The study included 51 patients who had undergone Orbera® IGB placement between September 2014 and February 2016. Inclusion criteria were age between 18 and 65 years; body mass index (BMI 28-35 with severe obesity-related disorders; or BMI 35-40. The IGB was removed 6 months later. All patients were followed for a minimum period of 6-12 months. Results: Of 51 patients, 16 were excluded (7 due to intolerance and 35 patients entered the study, of which 83% were followed for more than 6-12 months. The average weight loss (WL and % excess WL (%EWL after 6 months of treatment were 11.94 kg and 42.16%, respectively. At 6-12 months, after removal of the IGB, the mean WL was 8.25 kg and %EWL was 30.27%. Nineteen patients attained a WL of ≥10% the baseline value at IGB removal and 12 maintained their weight below this threshold during the 6-12 following months. Conclusions: After temporary IGB implantation in overweight or obese individuals, a WL that was ≥10% of weight at baseline was achieved in 54.3% and sustained at 6-12 months in 41.4% of participants. IGBs are an attractive intermediate option between diet and exercise programs and bariatric surgery. In general, IGB placement is a safe and well-tolerated procedure.

  2. Entropic sampling of simple polymer models within Wang-Landau algorithm

    International Nuclear Information System (INIS)

    Vorontsov-Velyaminov, P N; Volkov, N A; Yurchenko, A A

    2004-01-01

    In this paper we apply a new simulation technique proposed in Wang and Landau (WL) (2001 Phys. Rev. Lett. 86 2050) to sampling of three-dimensional lattice and continuous models of polymer chains. Distributions obtained by homogeneous (unconditional) random walks are compared with results of entropic sampling (ES) within the WL algorithm. While homogeneous sampling gives reliable results typically in the range of 4-5 orders of magnitude, the WL entropic sampling yields them in the range of 20-30 orders and even larger with comparable computer effort. A combination of homogeneous and WL sampling provides reliable data for events with probabilities down to 10 -35 . For the lattice model we consider both the athermal case (self-avoiding walks, SAWs) and the thermal case when an energy is attributed to each contact between nonbonded monomers in a self-avoiding walk. For short chains the simulation results are checked by comparison with the exact data. In WL calculations for chain lengths up to N = 300 scaling relations for SAWs are well reproduced. In the thermal case distribution over the number of contacts is obtained in the N-range up to N = 100 and the canonical averages - internal energy, heat capacity, excess canonical entropy, mean square end-to-end distance - are calculated as a result in a wide temperature range. The continuous model is studied in the athermal case. By sorting conformations of a continuous phantom freely joined N-bonded chain with a unit bond length over a stochastic variable, the minimum distance between nonbonded beads, we determine the probability distribution for the N-bonded chain with hard sphere monomer units over its diameter a in the complete diameter range, 0 ≤ a ≤ 2, within a single ES run. This distribution provides us with excess specific entropy for a set of diameters a in this range. Calculations were made for chain lengths up to N = 100 and results were extrapolated to N → ∞ for a in the range 0 ≤ a ≤ 1.25

  3. Effects of vegetation restoration on the aggregate stability and distribution of aggregate-associated organic carbon in a typical karst gorge region

    Science.gov (United States)

    Tang, F. K.; Cui, M.; Lu, Q.; Liu, Y. G.; Guo, H. Y.; Zhou, J. X.

    2015-08-01

    Changes in soil utilization significantly affect aggregate stability and aggregate-associated soil organic carbon (SOC). A field investigation and indoor analysis were conducted in order to study the soil aggregate stability and organic carbon distribution in the water-stable aggregates (WSA) of the bare land (BL), grassland (GL), shrubland (SL), and woodland (WL) in a typical karst gorge region. The results indicated that the BL, GL, SL, and WL were dominated by particles with sizes > 5 mm under dry sieving treatment, and that the soil aggregate contents of various sizes decreased as the particle size decreased. In addition, the BL, GL, SL, and WL were predominantly comprised of WSA sieving treatment, and that the WSA contents initially increased, then decreased, and then increased again as the particle size decreased. Furthermore, at a soil depth of 0-60 cm, the mean weight diameter (MWD), geometrical mean diameter (GMD), and fractal dimensions (D) of the dry aggregates and water-stable aggregates in the different types of land were ranked, in descending order, as WL > GL > SL > BL. The contents of WSA > 0.25 mm, MWD and GMD increased significantly, in that order, and the percentage of aggregate destruction (PAD) and fractal dimensions decreased significantly as the soil aggregate stability improved. The results of this study indicated that, as the SOC contents increased after vegetation restoration, the average SOC content of WL was 2.35, 1.37, and 1.26 times greater than that in the BL, GL, and SL, respectively. The total SOC and SOC associated in WSA of various sizes were the highest at a soil depth of 0-20 cm. In addition, the SOC contents of the WSA increased as the soil aggregate sizes decreased. The SOC contents of the WSA aggregates aggregate SOC contents. The woodland and grassland facilitated WSA stability and SOC protection, thus, promoting the natural restoration of vegetation by reducing artificial disturbances could effectively restore the ecology

  4. Universal Linear Precoding for NBI-Proof Widely Linear Equalization in MC Systems

    Directory of Open Access Journals (Sweden)

    Donatella Darsena

    2007-09-01

    Full Text Available In multicarrier (MC systems, transmitter redundancy, which is introduced by means of finite-impulse response (FIR linear precoders, allows for perfect or zero-forcing (ZF equalization of FIR channels (in the absence of noise. Recently, it has been shown that the noncircular or improper nature of some symbol constellations offers an intrinsic source of redundancy, which can be exploited to design efficient FIR widely-linear (WL receiving structures for MC systems operating in the presence of narrowband interference (NBI. With regard to both cyclic-prefixed and zero-padded transmission techniques, it is shown in this paper that, with appropriately designed precoders, it is possible to synthesize in both cases WL-ZF universal equalizers, which guarantee perfect symbol recovery for any FIR channel. Furthermore, it is theoretically shown that the intrinsic redundancy of the improper symbol sequence also enables WL-ZF equalization, based on the minimum mean output-energy criterion, with improved NBI suppression capabilities. Finally, results of numerical simulations are presented, which assess the merits of the proposed precoding designs and validate the theoretical analysis carried out.

  5. Suppression of cavitation in melted tungsten by doping with lanthanum oxide

    International Nuclear Information System (INIS)

    Yuan, Y.; Lu, G.H.; Xu, B.; Fu, B.Q.; Xu, H.Y.; Li, C.; Jia, Y.Z.; Qu, S.L.; Liu, W.; Greuner, H.; Böswirth, B.; Luo, G.-N.

    2014-01-01

    Melting and boiling behaviour of pure tungsten and 1 wt% lanthanum-oxide-doped tungsten (WL10) are investigated, focusing on the material selection with respect to material loss induced by cavitation. Melting experiments under high heat loads are carried out in the high heat flux facility GLADIS. Pulsed hydrogen neutral beams with heat flux of 10 and 23 MW m −2 are applied onto the adiabatically loaded samples for intense surface melting. Melt layer of the two tungsten grades exhibit different microstructure characteristics. Substantive voids owing to cavitation in the liquid phase are observed in pure W and lead to porous resolidified material. However, little cavitation bubbles can be found in the dense resolidified layer of WL10. In order to find out the gaseous sources, vapour collection is performed and the components are subsequently detected. Based on the observations and analyses, the microstructure evolutions corresponding to melting and vapourization behaviour of the two tungsten grades are tentatively described, and furthermore, the underlying mechanisms of cavitation in pure W and its suppression in WL10 are discussed. (paper)

  6. Monitoring of Level of Radiation Hazards to the Community in the Settlement Around the Incandescent Gas Mantle Factory

    International Nuclear Information System (INIS)

    Suryawati

    2000-01-01

    The analyze of radiation internal hazards level of thoron (Rn-220) and its daughter to the community settlement around the incandescent gas mantle factory. The radiation hazard level can be indicated in the form of working level (WL) and sffsctive dose lungs received by the community. The working level and effective dose lungs is got from the measurement of radioactivity level of thoron (Rn-220) and its daugther and by using the mathematical formula calculation. The measurement of thoron radioactive concentration and its daughter. The value of woking level obtained, performance level for community range from 0,001-0,013 WL, equivalent with dose range from 0,014- 0,467 mSv. From the research result, it can be identified that the radiation hazard, because exceed the mean value of threshold thorium radioactive nuclide and its daughter product of natural radiation in back ground per year for word mean i.e. 0,336 mSv, but the value of this research result is far below the allowed value limit for the community is 0,12 WL and 1 mSv/year

  7. Artificial neural network model of pork meat cubes osmotic dehydratation

    Directory of Open Access Journals (Sweden)

    Pezo Lato L.

    2013-01-01

    Full Text Available Mass transfer of pork meat cubes (M. triceps brachii, shaped as 1x1x1 cm, during osmotic dehydration (OD and under atmospheric pressure was investigated in this paper. The effects of different parameters, such as concentration of sugar beet molasses (60-80%, w/w, temperature (20-50ºC, and immersion time (1-5 h in terms of water loss (WL, solid gain (SG, final dry matter content (DM, and water activity (aw, were investigated using experimental results. Five artificial neural network (ANN models were developed for the prediction of WL, SG, DM, and aw in OD of pork meat cubes. These models were able to predict process outputs with coefficient of determination, r2, of 0.990 for SG, 0.985 for WL, 0.986 for aw, and 0.992 for DM compared to experimental measurements. The wide range of processing variables considered for the formulation of these models, and their easy implementation in a spreadsheet calculus make it very useful and practical for process design and control.

  8. Sleep and Productivity Benefits of Digital Cognitive Behavioral Therapy for Insomnia: A Randomized Controlled Trial Conducted in the Workplace Environment.

    Science.gov (United States)

    Bostock, Sophie; Luik, Annemarie I; Espie, Colin A

    2016-07-01

    Evaluating digital cognitive behavioral therapy (dCBT) for insomnia in a workplace environment. Within a randomized controlled trial in a Fortune 500 company, we randomized 270 self-identified poor sleepers [180 M/90 F: mean age 33.6 years (23 to 56 years)] to dCBT (n = 135) or waiting list (WL, n = 135). dCBT comprised six online sessions delivered by an animated therapist. Major assessments were at baseline and posttreatment. Sleep Condition Indicator (SCI) scores were significantly higher for the dCBT group [interaction term: F (1,485) = 15.63, P < 0.0001], representing Cohen's d of 1.10 following dCBT (d = 0.34 for WL). On the Work Productivity and Impairment questionnaire, "presenteeism" demonstrated significant improvements following dCBT [F(1,485) = 10.99, P = 0.001: d = 0.64 for dCBT, d = 0.09 for WL]. Effects for "abseenteeism" failed to reach statistical significance (P = 0.101). dCBT is effective in improving sleep and work-based productivity in adults with insomnia.

  9. Relationships of solar radiation and vapour pressure deficit with photosynthesis and water relations in dry-land pigeon pea

    International Nuclear Information System (INIS)

    Subramanian, V.B.; Venkateswarlu, S.; Maheswari, M.; Sankar, G.R.M.

    1994-01-01

    A study was undertaken to compare the relationships of photosynthetically active radiation (PAR) and vapour pressure deficit (VPD) with carbon assimilation and water relations of dry-land pigeon pea at the vegetative and reproductive phases. Photosynthetic rate (Pn), transpiration rate (T), leaf water potential (wL), and stomatal conductance (gs) were measured at 7- to 10-day intervals from 1 month after seedling until a fortnight before harvest during two seasons. Generally, Pn, T, and gs were higher and wL was lower during the reproductive than during the vegetative phase. At high PAR and VPD, Pn, T, wL, and gs decreased. The decrease in the T at high PAR was smaller during the reproductive phase. Growth of dry-land pigeon pea was affected not only during periods of water stress which was associated with high PAR and high VPD but also under conditions of favourable plant water status which were associated with less than optimal levels of PAR. It also showed transpiration efficiency (TE) was lower during the pod-filling than during the vegetative phase, when PAR was optimum

  10. Modeling the dynamics of a non-limited and a self-limited gene drive system in structured Aedes aegypti populations.

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    Mathieu Legros

    Full Text Available Recently there have been significant advances in research on genetic strategies to control populations of disease-vectoring insects. Some of these strategies use the gene drive properties of selfish genetic elements to spread physically linked anti-pathogen genes into local vector populations. Because of the potential of these selfish elements to spread through populations, control approaches based on these strategies must be carefully evaluated to ensure a balance between the desirable spread of the refractoriness-conferring genetic cargo and the avoidance of potentially unwanted outcomes such as spread to non-target populations. There is also a need to develop better estimates of the economics of such releases. We present here an evaluation of two such strategies using a biologically realistic mathematical model that simulates the resident Aedes aegypti mosquito population of Iquitos, Peru. One strategy uses the selfish element Medea, a non-limited element that could permanently spread over a large geographic area; the other strategy relies on Killer-Rescue genetic constructs, and has been predicted to have limited spatial and temporal spread. We simulate various operational approaches for deploying these genetic strategies, and quantify the optimal number of released transgenic mosquitoes needed to achieve definitive spread of Medea-linked genes and/or high frequencies of Killer-Rescue-associated elements. We show that for both strategies the most efficient approach for achieving spread of anti-pathogen genes within three years is generally to release adults of both sexes in multiple releases over time. Even though females in these releases should not transmit disease, there could be public concern over such releases, making the less efficient male-only release more practical. This study provides guidelines for operational approaches to population replacement genetic strategies, as well as illustrates the use of detailed spatial models to

  11. Genetic Polymorphisms and Weight Loss in Obesity: A Randomised Trial of Hypo-Energetic High- versus Low-Fat Diets

    Science.gov (United States)

    Sørensen, Thorkild I. A; Boutin, Philippe; Taylor, Moira A; Larsen, Lesli H; Verdich, Camilla; Petersen, Liselotte; Holst, Claus; Echwald, Søren M; Dina, Christian; Toubro, Søren; Petersen, Martin; Polak, Jan; Clément, Karine; Martínez, J. Alfredo; Langin, Dominique; Oppert, Jean-Michel; Stich, Vladimir; Macdonald, Ian; Arner, Peter; Saris, Wim H. M; Pedersen, Oluf; Astrup, Arne; Froguel, Philippe

    2006-01-01

    Objectives: To study if genes with common single nucleotide polymorphisms (SNPs) associated with obesity-related phenotypes influence weight loss (WL) in obese individuals treated by a hypo-energetic low-fat or high-fat diet. Design: Randomised, parallel, two-arm, open-label multi-centre trial. Setting: Eight clinical centres in seven European countries. Participants: 771 obese adult individuals. Interventions: 10-wk dietary intervention to hypo-energetic (−600 kcal/d) diets with a targeted fat energy of 20%–25% or 40%–45%, completed in 648 participants. Outcome Measures: WL during the 10 wk in relation to genotypes of 42 SNPs in 26 candidate genes, probably associated with hypothalamic regulation of appetite, efficiency of energy expenditure, regulation of adipocyte differentiation and function, lipid and glucose metabolism, or production of adipocytokines, determined in 642 participants. Results: Compared with the noncarriers of each of the SNPs, and after adjusting for gender, age, baseline weight and centre, heterozygotes showed WL differences that ranged from −0.6 to 0.8 kg, and homozygotes, from −0.7 to 3.1 kg. Genotype-dependent additional WL on low-fat diet ranged from 1.9 to −1.6 kg in heterozygotes, and from 3.8 kg to −2.1 kg in homozygotes relative to the noncarriers. Considering the multiple testing conducted, none of the associations was statistically significant. Conclusions: Polymorphisms in a panel of obesity-related candidate genes play a minor role, if any, in modulating weight changes induced by a moderate hypo-energetic low-fat or high-fat diet. PMID:16871334

  12. Use of the cellular model of body composition to describe changes in body water compartments after total fasting, very low calorie diet and low calorie diet in obese men.

    Science.gov (United States)

    Siervo, M; Faber, P; Gibney, E R; Lobley, G E; Elia, M; Stubbs, R J; Johnstone, A M

    2010-05-01

    The cellular model of body composition divides the body in body cell mass (BCM), extracellular solids and extracellular fluids. This model has been infrequently applied for the evaluation of weight loss (WL) programmes. (1) To assess changes in body compartments in obese men undergoing fasting, very low calorie diet (VLCD) and low calorie diet (LCD); (2) to evaluate two cellular models for the determination of changes in BCM, fat mass (FM) and body fluids. Three groups of six, obese men participated in a total fast (F) for 6 days, a VLCD (2.5 MJ per day) for 3 weeks or an LCD (5.2 MJ per day) for 6 weeks. Body composition was measured at baseline and after small ( approximately 5%) and moderate ( approximately 10%) WL. FM was measured using a four-compartment model. Total body water (TBW) and extracellular water (ECW) were, respectively, measured by deuterium and sodium bromide dilution and intracellular water (ICW) calculated by difference. Two cellular models were used to measure BCM, FM and body fluids distribution. After about 5%WL changes in TBW were F=-3.2+/-1.2 kg (Pfasting (+1.5+/-3.1 kg, n.s.), decreased during the VLCD (-2.0+/-1.5 kg, Pfasting (-4.7+/-3.9 kg, Pfasting group and it was directly associated with changes in ICW. After a 6-day period of fasting we observed more ICW losses and less fat mobilization compared with VLCD and LCD. The cellular model of body composition is suitable for the characterization of changes in body fluids distribution during WL.

  13. [PREDICTORS OF WEIGHT LOSS AND FAT IN THE DIETARY MANAGEMENT: SEX, AGE, BMI AND CONSULTING ASSISTANCE].

    Science.gov (United States)

    Reig García-Galbis, Manuel; Rizo Baeza, Mercedes; Cortés Castell, Ernesto

    2015-09-01

    WL%: percentage of weight loss; % FL: percentage fat loss; PNLWF: patients who lose weight or fat; PLWF: patients who lose weight and fat. assess whether the% WL and FL% in the dietary treatment was affected by gender, age, BMI and assistance to the query. 4,700 consultations, 670 patients (BMI ≥25), in the south-east of Spain (2006-12). Balanced and hypo-caloric diet was used. Two types of patients: PNLWF and PLWF (91.9%). in PLWF, men and those attending a greater number of occasions to the consultation have shown a greater loss against women (%FL: 23.0 vs 14.3%, p = 0.000; %WL: 7.7 vs 6.6%, p = 0.020), and those who attend less frequently (%FL: 19.1 vs 7.3%, p = 0.000; %WL: 7.8 vs 2.9%, p = 0.000). Multinomial regression analysis (PNLWF / PLWF) indicates that only attend more than one and a half to the consultation is a factor in the loss, OR 8.3 (IC 95% 4.5-15.1; p = 0.000). the body fat measurement provides additional information lost weight; Most patients attend more than six weeks, obtained a high %FL; attendance is a predictor of loss; the %FL indicates that the dietary management plays a major role in the resolution of this pathology; It is recommended to design practical schemes of action process nutritionists according to the IMCI and variable. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  14. Effects of positive emotion, extraversion, and dopamine on cognitive stability-flexibility and frontal EEG asymmetry.

    Science.gov (United States)

    Wacker, Jan

    2018-01-01

    The influence of positive emotions on the balance between cognitive stability and flexibility has been suggested to (a) differ among various positive emotional/motivational states (e.g., of varying approach motivation intensity), and (b) be mediated by brain dopamine (DA). Frontal EEG alpha asymmetry (ASY) is considered an indicator of approach motivational states and may be modulated by DA. The personality trait of extraversion is strongly linked to positive emotions and is now thought to reflect DA-based individual differences in incentive/approach motivation. The present study independently manipulated positive emotion (high approach wanting-expectancy [WE] vs. low approach warmth-liking [WL]) and dopamine (placebo vs. DA D2 blocker sulpiride) to examine their effects on both cognitive stability-flexibility and emotion-related ASY changes. The results showed numerically lower stability-flexibility in WE versus WL under placebo and a complete reversal of this effect under the D2 blocker, no differentiation between WE and WL groups in terms of emotion-related ASY change, but an association between self-reported WE and WL and ASY changes toward left and right frontal cortical activity, respectively. Finally, extraversion was positively associated with both stability-flexibility and ASY changes toward left frontal cortical activity under placebo, and these associations were completely reversed under the D2 blocker. The results (a) support a dopaminergic basis for frontal EEG asymmetry, extraversion, and the modulating effect of positive emotions on stability-flexibility, and (b) extend previous reports of cognitive differences between introverts and extraverts. © 2017 Society for Psychophysiological Research.

  15. LoCuSS: THE SUNYAEV-ZEL'DOVICH EFFECT AND WEAK-LENSING MASS SCALING RELATION

    Energy Technology Data Exchange (ETDEWEB)

    Marrone, Daniel P.; Carlstrom, John E.; Gralla, Megan; Greer, Christopher H.; Hennessy, Ryan; Leitch, Erik M.; Plagge, Thomas [Kavli Institute for Cosmological Physics, University of Chicago, Chicago, IL 60637 (United States); Smith, Graham P. [School of Physics and Astronomy, University of Birmingham, Edgbaston, Birmingham, B15 2TT (United Kingdom); Okabe, Nobuhiro [Astronomical Institute, Tohoku University, Aramaki, Aoba-ku, Sendai, 980-8578 (Japan); Bonamente, Massimiliano; Hasler, Nicole [Department of Physics, University of Alabama, Huntsville, AL 35899 (United States); Culverhouse, Thomas L. [Radio Astronomy Lab, 601 Campbell Hall, University of California, Berkeley, CA 94720 (United States); Hawkins, David; Lamb, James W.; Muchovej, Stephen [Owens Valley Radio Observatory, California Institute of Technology, Big Pine, CA 93513 (United States); Joy, Marshall [Space Science-VP62, NASA Marshall Space Flight Center, Huntsville, AL 35812 (United States); Martino, Rossella; Mazzotta, Pasquale [Dipartimento di Fisica, Universita degli Studi di Roma ' Tor Vergata' , via della Ricerca Scientifica 1, 00133, Roma (Italy); Miller, Amber [Columbia Astrophysics Laboratory, Columbia University, New York, NY 10027 (United States); Mroczkowski, Tony, E-mail: dmarrone@email.arizona.edu [Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104 (United States); and others

    2012-08-01

    We present the first weak-lensing-based scaling relation between galaxy cluster mass, M{sub WL}, and integrated Compton parameter Y{sub sph}. Observations of 18 galaxy clusters at z {approx_equal} 0.2 were obtained with the Subaru 8.2 m telescope and the Sunyaev-Zel'dovich Array. The M{sub WL}-Y{sub sph} scaling relations, measured at {Delta} = 500, 1000, and 2500 {rho}{sub c}, are consistent in slope and normalization with previous results derived under the assumption of hydrostatic equilibrium (HSE). We find an intrinsic scatter in M{sub WL} at fixed Y{sub sph} of 20%, larger than both previous measurements of M{sub HSE}-Y{sub sph} scatter as well as the scatter in true mass at fixed Y{sub sph} found in simulations. Moreover, the scatter in our lensing-based scaling relations is morphology dependent, with 30%-40% larger M{sub WL} for undisturbed compared to disturbed clusters at the same Y{sub sph} at r{sub 500}. Further examination suggests that the segregation may be explained by the inability of our spherical lens models to faithfully describe the three-dimensional structure of the clusters, in particular, the structure along the line of sight. We find that the ellipticity of the brightest cluster galaxy, a proxy for halo orientation, correlates well with the offset in mass from the mean scaling relation, which supports this picture. This provides empirical evidence that line-of-sight projection effects are an important systematic uncertainty in lensing-based scaling relations.

  16. Combined osmotic dehydration and drying process of pirarucu (Arapaima gigas) fillets.

    Science.gov (United States)

    Martins, Mayara Galvão; da Silva Pena, Rosinelson

    2017-09-01

    The osmotic dehydration (OD) and complementary drying of pirarucu ( Arapaima gigas ) fillets were studied. Pieces of the dorsal portion of pirarucu (60 mm × 20 mm × 10 mm) underwent OD in a binary solution (NaCl-water) with the application of vacuum pulse following a central rotatable composite design. The effect of the following process variables was assessed: temperature (20-40 °C), osmotic solution concentration (15-25% NaCl), and vacuum pulse pressure (7-101 kPa) on water loss (WL), solid gain (SG), and water activity (a w ). OD kinetics was obtained and the Peleg model was fitted to WL and SG data. The osmotically dehydrated pirarucu was dried (40-70 °C) in a fixed-bed dryer and mathematical models were fitted to the drying data. The optimal operational condition for the OD process was 35 °C, solution with 25% NaCl, and atmospheric pressure, which yielded WL of 14.87 ± 1.46%, SG of 8.56 ± 0.45%, and a w of 0.87 ± 0.02. The Peleg model efficiently predicted the WL and SG kinetics. The increase in the water loss in drying was more evident at low temperatures (40-50 °C) with effective diffusivity ranging from 10.85 × 10 -9 to 12.30 × 10 -9 m 2 /s. The Midilli and Page models efficiently predicted the drying kinetics.

  17. Entre el saber y la verdad,el enigma del sujeto.

    Directory of Open Access Journals (Sweden)

    Luz Stella Alzate.

    2002-03-01

    Full Text Available El presente texto constituye un intento de dimensionar la posición del sujeto tanto para la filosofía como papa el psicoanálisis, como un ser estructuralmente escindido. Esto es, como un ser constituido a partir de una división estructural entre el saber y la verdad, en medio de los cuales se prefiguran el mito y el enigma como estructuras discursivas. Partiendo de esta división, se hace un breve análisis de la tragedia de Medea, de Eurípides, de la cual se obtienen algunos elementos para ilustrar la posición de algunas mujeres en lo que respecta al fenómeno de la violencia intrafamiliar.

  18. Potential of acoustic monitoring for safety assessment of primary system

    International Nuclear Information System (INIS)

    Olma, B.J.

    1997-01-01

    Safety assessment of the primary system and its components with respect to their mechanical integrity is increasingly supported by acoustic signature analysis during power operation of the plants. Acoustic signals of Loose Parts Monitoring System sensors are continuously monitored by dedicated digital systems for signal bursts associated with metallic impacts. Several years of ISTec/GRS experience and the practical use of its digital systems MEDEA and RAMSES have shown that acoustic monitoring is very successful for detecting component failures at an early stage. Advanced powerful tools for classification and acoustic evaluation of burst signals have recently been realized. The paper presents diagnosis experiences of BWR's and PWR's safety assessment. (author). 7 refs, 8 figs

  19. Differential responses of growth and photosynthesis in Cyamopsis tetragonoloba grown under ultraviolet-B and supplemental long-wavelength radiations

    International Nuclear Information System (INIS)

    Lingakumar, K.; Kulandaivelu, G.

    1998-01-01

    Cyamopsis tetragonoloba seedlings were subjected to continuous ultraviolet (UV)B radiation for 18 h and post-irradiated with 'white light' (WL) and UV-A enhanced fluorescent radiations. UV-B treatment alone reduced plant growth, pigment content, and photosynthetic activities. Supplementation of UV-A promoted the overall seedling growth and enhanced the synthesis of chlorophyll and carotenoids with a relatively high photosystem 1 activity. Post UV-B irradiation under WL failed to photoreactivate the LTV-B damage whereas a positive photoregulatory effect of UV-A was noticed in electron transport rates and low temperature fluorescence emission spectra

  20. Source identification of heavy metals in atmospheric dust using Platanus orientalis L. leaves as bioindicator

    Directory of Open Access Journals (Sweden)

    Samira Norouzi

    2015-07-01

    Full Text Available Studies on atmospheric dust have been limited by the high cost of instrumental monitoring methods and also sampling difficulties. The use of organisms acting as bioaccumulators has recently been proposed. In this study, the leaves of Platanus orientalis L., as a possible biomonitor of heavy metals in atmospheric dust, were evaluated to understand the likely source(s of pollution in Isfahan, Iran. Concentration of Zn, Cu, Ni and Mn and Magnetic susceptibility (χlf were determined in washed (WL and unwashed leaves (UL, monthly sampled from May to Nov., 2012. By subtracting the amount of metal concentrations and χlf in UL and WL, the amount of these parameters in dust deposited on the leaves (UL-WL were calculated. Enrichment factor analysis (EF, correlation coeficient, principal component analysis (PCA and cluster analysis (CA on the UL-WL data were employed to trace the heavy metals sources. Results showed that the metal concentration in UL and WL in primary sampling times was not statistically different. As time passed, this difference became more noticeable. Seasonal accumulation trends of elements concentration in UL-WL, referred to as accumulative biomonitors showing the accumulation of dust on the leaves are considerable and the contamination of plants by metal occurs mainly by retention of particulate matter. All the heavy metals are well correlated with χlf, indicating the potential of magnetic measurement as an inexpensive and less laborious method to estimate heavy metals. Cu and Zn exhibited a very strong correlation with each other and the highest correlation with χlf, suggesting an anthropogenic nature of these two metals. High EF of Cu and Zn showed that anthropogenic sources contribute a substantial amount of these metals to dust deposited on leaves. Whereas, less EF for Mn and Ni shows that natural source and local polluted soils might be the main origins of these metals. PCA results showed 2 principal components. Factor 1 with

  1. Radiological impact of exposure to radon-thoron and their progeny present in the environment of fly ash dumping site in Faridabad (Haryana)

    International Nuclear Information System (INIS)

    Gupta, Nitin; Kant, Krishan; Garg, Maneesha

    2013-01-01

    Radon-Thoron and their Progeny monitoring was carried out in dwellings near fly ash dumping sites in Faridabad (Haryana), as it is very important from health and hygiene point of view of the occupants. For the measurements, the track etch technique was used. The dosimeter employed for the measurement consisted of twin chamber systems with LR-115 Type II SSNTDs placed on the two sides of the central partition inside the cup and a bare film placed outside it. The detectors were exposed in the mixed field of radon-thoron in the environment of dwellings. The detectors were placed in about 100 dwellings and the choice of the dwelling was random. The value of PAEC, radon concentration, annual exposure, annual effective dose in the dwellings near fly ash dumping sites in District Faridabad (Haryana) varied from 1.34 mWL to 14.05 mWL with an average value of (4.95 0.85) mWL, 12.41 Bqm -3 to 129.91 Bqm -3 with an average value of (45.77 7.87) Bqm -3 , 0.55 10 -1 WLM to 5.83 10 -1 WLM with an average value of (2.04 0.28) 10 -1 WLM and 0.21 mSv to 2.23 mSv with an average value of (0.79 0.13) mSv. The value of PAEC, thoron concentration, annual exposure, annual effective dose in the dwellings near fly ash dumping sites in District Faridabad (Haryana) varied from 1.34 mWL to 14.0 SmWL with an average value of (4.95 0.85) mWL, 1.16 Bq/m 3 to 65.08 Bq/m 3 with an average value of (32.77 7.87) Bqm -3 , 0.55 10 -1 WLM to 5.83 10 -1 WLM with an average value of (2.04 0.28) 10 -1 WLM and 0.21 mSv to 2.23 mSv with an average value of (0.79 0.13) mSv. The measurements indicate that the radon concentration was below the safety levels (action levels) as recommended by various regulatory bodies. The maximum value of 129.91 Bqm -3 was found in a cave inside a temple, where there was no ventilation. The different values of radon concentrations are due to different ventilation conditions and house structures. The radon concentration was found to decrease with the increase in distance of the

  2. Influence of land use on bacterial and archaeal diversity and community structures in three natural ecosystems and one agricultural soil.

    Science.gov (United States)

    Lynn, Tin Mar; Liu, Qiong; Hu, Yajun; Yuan, Hongzhao; Wu, Xiaohong; Khai, Aye Aye; Wu, Jinshui; Ge, Tida

    2017-07-01

    Studying shifts in microbial communities under different land use can help in determining the impact of land use on microbial diversity. In this study, we analyzed four different land-use types to determine their bacterial and archaeal diversity and abundance. Three natural ecosystems, that is, wetland (WL), grassland (GL), and forest (FR) soils, and one agricultural soil, that is, tea plantation (TP) soil, were investigated to determine how land use shapes bacterial and archaeal diversity. For this purpose, molecular analyses, such as quantitative polymerase chain reaction (Q-PCR), 16S rRNA gene sequencing, and terminal restriction fragment length polymorphism (T-RFLP), were used. Soil physicochemical properties were determined, and statistical analyses were performed to identify the key factors affecting microbial diversity in these soils. Phylogenetic affiliations determined using the Ribosomal Database Project (RDP) database and T-RFLP revealed that the soils had differing bacterial diversity. WL soil was rich in only Proteobacteria, whereas GR soil was rich in Proteobacteria, followed by Actinobacteria. FR soil had higher abundance of Chloroflexi species than these soils. TP soil was rich in Actinobacteria, followed by Chloroflexi, Acidobacteria, Proteobacteria, and Firmicutes. The archaeal diversity of GL and FR soils was similar in that most of their sequences were closely related to Nitrososphaerales (Thaumarchaeota phylum). In contrast, WL soil, followed by TP soil, had greater archaeal diversity than other soils. Eight different archaeal classes were found in WL soil, and Pacearchaeota class was the richest one. The abundance of bacterial and archaeal 16S rRNA gene copies in WL and GL soils was significantly higher than that in FR and TP soils. Redundancy analysis showed that bacterial diversity was influenced by abiotic factors, e.g., total organic carbon and pH, whereas total nitrogen, pH, and cation exchange capacity (CEC) significantly affected

  3. An Improved BeiDou-2 Satellite-Induced Code Bias Estimation Method

    Directory of Open Access Journals (Sweden)

    Jingyang Fu

    2018-04-01

    Full Text Available Different from GPS, GLONASS, GALILEO and BeiDou-3, it is confirmed that the code multipath bias (CMB, which originate from the satellite end and can be over 1 m, are commonly found in the code observations of BeiDou-2 (BDS IGSO and MEO satellites. In order to mitigate their adverse effects on absolute precise applications which use the code measurements, we propose in this paper an improved correction model to estimate the CMB. Different from the traditional model which considering the correction values are orbit-type dependent (estimating two sets of values for IGSO and MEO, respectively and modeling the CMB as a piecewise linear function with a elevation node separation of 10°, we estimate the corrections for each BDS IGSO + MEO satellite on one hand, and a denser elevation node separation of 5° is used to model the CMB variations on the other hand. Currently, the institutions such as IGS-MGEX operate over 120 stations which providing the daily BDS observations. These large amounts of data provide adequate support to refine the CMB estimation satellite by satellite in our improved model. One month BDS observations from MGEX are used for assessing the performance of the improved CMB model by means of precise point positioning (PPP. Experimental results show that for the satellites on the same orbit type, obvious differences can be found in the CMB at the same node and frequency. Results show that the new correction model can improve the wide-lane (WL ambiguity usage rate for WL fractional cycle bias estimation, shorten the WL and narrow-lane (NL time to first fix (TTFF in PPP ambiguity resolution (AR as well as improve the PPP positioning accuracy. With our improved correction model, the usage of WL ambiguity is increased from 94.1% to 96.0%, the WL and NL TTFF of PPP AR is shorten from 10.6 to 9.3 min, 67.9 to 63.3 min, respectively, compared with the traditional correction model. In addition, both the traditional and improved CMB model have

  4. Study on seasonal variation of indoor radon, thoron and their progeny levels in Hassan District of Karnataka, India

    International Nuclear Information System (INIS)

    Srinivasa, E.; Rangswamy, D.R.; Sannappa, J.

    2015-01-01

    Radon, thoron and their progeny concentrations have been measured in different types of buildings at different locations for different seasons in Hassan city using time-integrated passive radon dosimeters containing LR-115 Type II solid state nuclear track detector exposed for four seasons of 3 months each covering a period of one year from October 2012 to September 2013. The radon and thoron activity concentration in summer season in the corresponding dwellings has been found to vary from 7.4 to 45.7 Bq m -3 and 5.4 to 34.9 Bqm -3 with a median of 23.59±11 Bqm -3 and 1447±8 Bq -3 respectively. The radon progeny concentrations varies from 0.4 to 4.1 mWL with an average value of 1.83±1 mWL, while thoron progeny concentrations vary from 0.3 to 3.2 mWL with an average value of 1.12±0.7 mWL respectively. The annual effective dose received due to radon, thoron and its progeny by the inhabitants in the dwellings under study has also been calculated which is found to vary from 0.320±0.4 to 1.860 ±1.1 mSv y -1 with an average value of 0.9576 ± 0.8 mSv y -1 . In general, the level of radon-thoron was observed highest in winter and lowest in summer. A detail analysis of radon and thoron distribution in different houses with seasonal variation is presented in this paper. From this study it is observed that, bathrooms and kitchens have significantly higher radon concentrations as compared to other rooms in the dwellings. (author)

  5. Measurment of radon, thoron and their progeny in indoor environment of Mohali, Punjab, Northern India, using pinhole dosimeters

    Directory of Open Access Journals (Sweden)

    Mehta Vimal

    2016-01-01

    Full Text Available The health hazards of radon and its decay products above certain levels are well known. However, for any preventive measures to be taken, we have to be aware of radon levels of that particular area. Measurement of radon and its decay products in indoor environments is an important aspect of assessing indoor air quality and health conditions associated with it. Keeping this in mind, measurements of radon, thoron and their progeny concentrations were carried out in Mohali, Northern India, using pinhole-based twin cup dosimeters. Radon exhalation rates of soil samples in the dwellings/areas were measured via an active technique of a continuous radon monitor. The indoor radon concentration in Mohali varied from 15.03 ± 0.61 Bq/m3 to 39.21 ± 1.46 Bq/m3 with an average of 26.95 Bq/m3 ,while thoron concentration in the same dwellings varied from 9.62 ± 0.54 Bq/m3 to 52.84 ± 2.77 Bq/m3 with an average of 31.09 Bq/m3. Radon progeny levels in dwellings under study varied from 1.63 to 4.24 mWL, with an average of 2.94 mWL, while thoron progeny levels varied from 0.26 to 1.43 mWL , with an average of 0.84 mWL. The annual dose received by the inhabitants of dwellings under study varied from 0.78 to 2.36 mSv, with an average of 1.61 mSv. The in situ gamma dose rate varied from 0.12 to 0.32 mSv/h.

  6. On the efficient warm white-light emission from nano-sized Y{sub 2}O{sub 3}

    Energy Technology Data Exchange (ETDEWEB)

    Cesaria, M., E-mail: maura.cesaria@le.infn.it [Department of Mathematics and Physics “E. De Giorgi”, University of Salento, Lecce (Italy); Collins, J. [Wheaton College, Norton, MA (United States); Di Bartolo, B. [Department of Physics, Boston College, Chestnut Hill, MA (United States)

    2016-01-15

    We consider the reported emission of white light (WL) in the spectral range from 400 to beyond 900 nm induced by monochromatic infrared light (803.5 and 975 nm) continuous wave excitation of nominally un-doped yttrium oxide (Y{sub 2}O{sub 3}) nano-powders. Based on the experimental evidence, such an emission feature is a nano-scale phenomenon, resembles very closely the emission from an incandescent lamp (mimicking the sunlight, i.e., the most comfortable light to human eyes) and exhibits very high efficiency (864 lum/W) and nearly theoretical (i.e., 99) color rendering index. At the fundamental level, the origin of this phenomenon is still unexplained. In this paper we address the fundamental questions raised by the reported occurrence of WL emission from Y{sub 2}O{sub 3} nanopowders and attempt an interpretation at a more fundamental level. In particular we focus on the multiphoton-absorption and nonexponential decay patterns of the reported WL emission as starting points to formulate models and interpretations of the experimental occurrences still lacking in the literature. Our discussion invokes the electronic dispersion of Y{sub 2}O{sub 3} and nanoscale effects, which is supported by the experimental evidence according to which the observed warm WL emission is a nanoscale phenomenon with properties that only can be explained by nanoscale physics. - Highlights: • Emission of white light from 400 to beyond 900 nm induced by infrared light of un-doped Y{sub 2}O{sub 3} nano-powders. • The emission feature resembles very closely the emission from an incandescent lamp. • The observed emission properties only can be explained by nanoscale physics.

  7. Photoluminescence investigation of strictly ordered Ge dots grown on pit-patterned Si substrates

    International Nuclear Information System (INIS)

    Brehm, Moritz; Grydlik, Martyna; Tayagaki, Takeshi; Schmidt, Oliver G; Langer, Gregor; Schäffler, Friedrich

    2015-01-01

    We investigate the optical properties of ordered Ge quantum dots (QDs) by means of micro-photoluminescence spectroscopy (PL). These were grown on pit-patterned Si(001) substrates with a wide range of pit-periods and thus inter QD-distances (425–3400 nm). By exploiting almost arbitrary inter-QD distances achievable in this way we are able to choose the number of QDs that contribute to the PL emission in a range between 70 and less than three QDs. This well-defined system allows us to clarify, by PL-investigation, several points which are important for the understanding of the formation and optical properties of ordered QDs. We directly trace and quantify the amount of Ge transferred from the surrounding wetting layer (WL) to the QDs in the pits. Moreover, by exploiting different pit-shapes, we reveal the role of strain-induced activation energy barriers that have to be overcome for charge carriers generated outside the dots. These need to diffuse between the energy minimum of the WL in and between the pits, and the one in the QDs. In addition, we demonstrate that the WL in the pits is already severely intermixed with Si before upright QDs nucleate, which further enhances intermixing of ordered QDs as compared to QDs grown on planar substrates. Furthermore, we quantitatively determine the amount of Ge transferred by surface diffusion through the border region between planar and patterned substrate. This is important for the growth of ordered islands on patterned fields of finite size. We highlight that the Ge WL-facets in the pits act as PL emission centres, similar to upright QDs. (paper)

  8. Determination of the thoron daughter working level by a one gross alpha-count

    International Nuclear Information System (INIS)

    Bigu, J.; Lau, W.K.

    1983-02-01

    A study has been done on the determination of the thoron daughter Working Level, WL(Tn), by a one gross α-count. The relationship between the gross α-count rate per unit of volume of air sampled and WL(Tn), denoted the F-factor, has been investigated as a function of sampling time, elapsed time from the end of the sampling period, i.e., waiting time, and the thoron daughter disequilibrium ratio [ThC]/[ThB]. It has been found that F depends on both the waiting time and [ThC]/[ThB]. If α-count measurements are made at least 300 min after the end of sampling, F changes by less than 10 percent over the full range of theoretical values of [ThC]/[ThB], i.e., from 0 to 1. The F-factor is independent of [ThC]/[ThB] at approximately 215 min after the end of sampling. This feature can be used to determine WL(Tn) with higher accuracy and at least 1.5 hr earlier than is commonly done using other one gross α-count methods reported in the literature

  9. Actual problems on protection in non-uranium mines of region Zletovo-Kratovo

    International Nuclear Information System (INIS)

    Hajdukovic, D.

    1983-01-01

    Besides lead-zinc layers in the mining region Zletovo-Kratovo the geologic composition contains uranium ore in traces too. So, an experimental uranium mine had existed there until 1968. The level of radioactivity in the pits of lead-zinc metal mines Zletovo and Sase has been controlled since 1961. Concentrations of radon 222 and its daughters were found to be within an extensive range from 185 Bq m 3 , namely 0.025 WL up to 3.7 x 10 4 Bq m 3 , namely 5 WL in mine Zletovo, i.e. a very high concentration was found to range up to 3.7 x 10 5 Bq m 3 , namely 50 WL in the new research areas in mine Sase. Natural way of ventilation mostly used in both mines showed to be useless for the most area of the pit, and temporary introduction of local mechanical ventilation has resulted in an unadequate and undurable lowering of high concentrations of radon and its daughters. Introduction of an adequate mechanical ventilation has become necessary a long time ago, but due to extended underground works and remote working places this would require a considerable investment and high skilfulness. (author)

  10. Effects of Neck-Specific Exercises Compared to Waiting List for Individuals With Chronic Whiplash-Associated Disorders: A Prospective, Randomized Controlled Study.

    Science.gov (United States)

    Peolsson, Anneli; Landén Ludvigsson, Maria; Tigerfors, Ann-Marie; Peterson, Gunnel

    2016-02-01

    To determine whether 3 months of neck-specific exercises (NSEs) could benefit individuals with chronic whiplash-associated disorder (WAD) who were on a waiting list (WL) for treatment. A prospective, randomized controlled study. Primary health care. Individuals (N=41; 31 women, 10 men; mean age ± SD, 38±11.2y) with chronic (6-36mo) WAD, grades 2 and 3, were analyzed. Patients were randomly assigned to NSEs or no treatment for 3 months. Neck-specific disability (Neck Disability Index [NDI]), neck pain (visual analog scale), general pain-related disability (Pain Disability Index [PDI]), self-perceived performance ability (Self-Efficacy Scale [SES]), and health-related quality of life (EuroQol 5 dimensions [EQ-5D]) were measured. NSEs significantly improved the NDI, SES, and EQ-5D compared with WL (P<.01). There was significant improvement (P<.0001) over time in all outcomes for NSEs, and apart from the PDI, significant worsening (P=.002-.0002) over time for the untreated group. NSEs were more beneficial than no intervention while on a WL for individuals with chronic WAD. Copyright © 2016 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  11. General Dental Practitioners’ Concept towards Using Radiography and Apex-Locators in Endodontics

    Science.gov (United States)

    Raoof, Maryam; Heidaripour, Maryam; Shahravan, Arash; Haghani, Jahangir; Afkham, Arash; Razifar, Mahsa; Mohammadizadeh, Sakineh

    2014-01-01

    Introduction: Despite being the gold standard as well as a routine technique in endodontics, radiographic working length (WL) determination owns many drawbacks. Electronic apex-locators (EALs) are recommended to complement radiographies. The aim of this study was to evaluate the perceptions of Iranian general dental practitioners (GDPs) towards using radiography and EAL. Methods and Materials: Three hundred and ninety one GDPs attending the 53th Iranian Dental Association Congress completed a questionnaire focusing on the use of radiography and EALs during the various stages of root canal treatment. The data was analyzed with the chi-square test with the level of significance set at 0.05. The results were then calculated as frequencies and percentages. Results: More than half of the GDPs reported using radiographs as the sole method for WL determination. A total of 30.4% of the practitioners were using the combined approach during root canal therapy of a single-rooted tooth, while 38.9% used this method in multi-rooted teeth. Approximately half of the respondents would not order follow-up radiographies after root canal treatment. Conclusion: Radiography continues to be the most common method for WL determination in Iran. PMID:25386209

  12. Surface morphology and structure of Ge layer on Si(111) after solid phase epitaxy

    Science.gov (United States)

    Yoshida, Ryoma; Tosaka, Aki; Shigeta, Yukichi

    2018-05-01

    The surface morphology change of a Ge layer on a Si(111) surface formed by solid phase epitaxy has been investigated with a scanning tunneling microscope (STM). The Ge film was deposited at room temperature and annealed at 400 °C or 600 °C. The STM images of the sample surface after annealing at 400 °C show a flat wetting layer (WL) with small three-dimensional islands on the WL. After annealing at 600 °C, the STM images show a surface roughening with large islands. From the relation between the average height of the roughness and the deposited layer thickness, it is confirmed that the diffusion of Ge atoms becomes very active at 600 °C. The Si crystal at the interface is reconstructed and the intermixing occurs over 600 °C. However, the intermixing is fairly restricted in the solid phase epitaxy growth at 400 °C. The surface morphology changes with the crystallization at 400 °C are discussed by the shape of the islands formed on the WL surface. It is shown that the diffusion of the Ge atoms in the amorphous phase is active even at 400 °C.

  13. Northwest Africa 10758: A New CV3 Chondrite Bearing a Giant CAI with Hibonite-Rich Wark-Lovering Rim

    Science.gov (United States)

    Ross, D. K.; Simon, J. I.; Zolensky, M.

    2017-01-01

    Northwest Africa (NWA) 10758 is a newly identified carbonaceous chondrite that is a Bali-like oxidized CV3. The large Ca-Al rich inclusion (CAI) in this sample is approx. 2.4 x 1.4 cm. The CAI is transitional in composition between type A and type B, with interior mineralogy dominated by melilite, plus less abundant spinel and Al-Ti rich diopside, and only very minor anorthite (Fig. 1A). This CAI is largely free of secondary alteration in the exposed section we examined, with almost no nepheline, sodalite or Ca-Fe silicates. The Wark-Lovering (WL) rim on this CAI is dominated by hibonite, with lower abundances of spinel and perovskite, and with hibonite locally overlain by melilite plus perovskite (as in Fig. 1B). Note that the example shown in 1B is exceptional. Around most of the CAI, hibonite + spinel + perovskite form the WL rim, without overlying melilite. The WL rim can be unusually thick, ranging from approx.20 microns up to approx. 150 microns. A well-developed, stratified accretionary rim infills embayments of the CAI, and thins over protuberances in the convoluted CAI surface.

  14. NWA10758: A New CV3 Chondrite Bearing a Giant CAI with Hibonite-Rich Wark-Lovering Rim

    Science.gov (United States)

    Ross, D. K.; Simon, J. I.; Zolensky, M.

    2017-01-01

    Northwest Africa (NWA) 10758 is a newly identified carbonaceous chondrite that is a Bali-like oxidized CV3. The large Ca-Al rich inclusion (CAI) in this sample is approx. 2.4 x 1.4 cm. The CAI is transitional in composition between type A and type B, with interior mineralogy dominated by melilite, plus less abundant spinel and Al-Ti rich diopside, and only very minor anorthite (Fig. 1A). This CAI is largely free of secondary alteration in the exposed section we examined, with almost no nepheline, sodalite or Ca-Fe silicates. The Wark-Lovering (WL) rim on this CAI is dominated by hibonite, with lower abundances of spinel and perovskite, and with hibonite locally overlain by melilite plus perovskite (as in Fig. 1B). Note that the example shown in 1B is exceptional. Around most of the CAI, hibonite + spinel + perovskite form the WL rim, without overlying melilite. The WL rim can be unusually thick, ranging from approx. 20 microns up to approx. 150 microns. A well-developed, stratified accretionary rim infills embayments of the CAI, and thins over protuberances in the convoluted CAI surface.

  15. Optimal updating magnitude in adaptive flat-distribution sampling.

    Science.gov (United States)

    Zhang, Cheng; Drake, Justin A; Ma, Jianpeng; Pettitt, B Montgomery

    2017-11-07

    We present a study on the optimization of the updating magnitude for a class of free energy methods based on flat-distribution sampling, including the Wang-Landau (WL) algorithm and metadynamics. These methods rely on adaptive construction of a bias potential that offsets the potential of mean force by histogram-based updates. The convergence of the bias potential can be improved by decreasing the updating magnitude with an optimal schedule. We show that while the asymptotically optimal schedule for the single-bin updating scheme (commonly used in the WL algorithm) is given by the known inverse-time formula, that for the Gaussian updating scheme (commonly used in metadynamics) is often more complex. We further show that the single-bin updating scheme is optimal for very long simulations, and it can be generalized to a class of bandpass updating schemes that are similarly optimal. These bandpass updating schemes target only a few long-range distribution modes and their optimal schedule is also given by the inverse-time formula. Constructed from orthogonal polynomials, the bandpass updating schemes generalize the WL and Langfeld-Lucini-Rago algorithms as an automatic parameter tuning scheme for umbrella sampling.

  16. Non-destructive equations to estimate the leaf area of Styrax pohlii and Styrax ferrugineus

    Directory of Open Access Journals (Sweden)

    MC Souza

    Full Text Available We developed linear equations to predict the leaf area (LA of the species Styrax pohlii and Styrax ferrugineus using the width (W and length (L leaf dimensions. For both species the linear regression (Y=α+bX using LA as a dependent variable vs. W × L as an independent variable was more efficient than linear regressions using L, W, L2 and W2 as independent variables. Therefore, the LA of S. pohlii can be estimated with the equation LA=0.582+0.683WL, while the LA of S. ferrugineus follows the equation LA=−0.666+0.704WL.

  17. A comparison of delayed self-heterodyne interference measurement of laser linewidth using Mach-Zehnder and Michelson interferometers.

    Science.gov (United States)

    Canagasabey, Albert; Michie, Andrew; Canning, John; Holdsworth, John; Fleming, Simon; Wang, Hsiao-Chuan; Aslund, Mattias L

    2011-01-01

    Linewidth measurements of a distributed feedback (DFB) fibre laser are made using delayed self heterodyne interferometry (DHSI) with both Mach-Zehnder and Michelson interferometer configurations. Voigt fitting is used to extract and compare the Lorentzian and Gaussian linewidths and associated sources of noise. The respective measurements are w(L) (MZI) = (1.6 ± 0.2) kHz and w(L) (MI) = (1.4 ± 0.1) kHz. The Michelson with Faraday rotator mirrors gives a slightly narrower linewidth with significantly reduced error. This is explained by the unscrambling of polarisation drift using the Faraday rotator mirrors, confirmed by comparing with non-rotating standard gold coated fibre end mirrors.

  18. Some remarks on exact methods for WL and 222Rn-daughter determination

    International Nuclear Information System (INIS)

    Groer, P.G.

    1977-01-01

    For an exact determination of the three 222 Rn-daughter concentrations (RaA, B and C) which properly weighted yield the Working Level, three equations relating observed counts (α or β) to these unknown concentrations have to be solved. The half-lives in the 222 Rn decay series, the type of decay and the counting errors, limit the suitable set of equations. Some aspects of two such exact methods are discussed

  19. Nitrogen biogeochemistry in the Adirondack Mountains of New York: hardwood ecosystems and associated surface waters

    International Nuclear Information System (INIS)

    Mitchell, Myron J.; Driscoll, Charles T.; Inamdar, Shreeram; McGee, Greg G.; Mbila, Monday O.; Raynal, Dudley J.

    2003-01-01

    Factors that regulate the fate of atmospherically deposited nitrogen to hardwood forests and subsequent transport to surface waters in the Adirondack region of New York are described. - Studies on the nitrogen (N) biogeochemistry in Adirondack northern hardwood ecosystems were summarized. Specific focus was placed on results at the Huntington Forest (HFS), Pancake-Hall Creek (PHC), Woods Lake (WL), Ampersand (AMO), Catlin Lake (CLO) and Hennessy Mountain (HM). Nitrogen deposition generally decreased from west to east in the Adirondacks, and there have been no marked temporal changes in N deposition from 1978 through 1998. Second-growth western sites (WL, PHC) had higher soil solution NO 3 - concentrations and fluxes than the HFS site in the central Adirondacks. Of the two old-growth sites (AMO and CLO), AMO had substantially higher NO 3 - concentrations due to the relative dominance of sugar maple that produced litter with high N mineralization and nitrification rates. The importance of vegetation in affecting N losses was also shown for N-fixing alders in wetlands. The Adirondack Manipulation and Modeling Project (AMMP) included separate experimental N additions of (NH 4 ) 2 SO 4 at WL, PHC and HFS and HNO 3 at WL and HFS. Patterns of N loss varied with site and form of N addition and most of the N input was retained. For 16 lake/watersheds no consistent changes in NO 3 - concentrations were found from 1982 to 1997. Simulations suggested that marked NO 3 - loss will only be manifested over extended periods. Studies at the Arbutus Watershed provided information on the role of biogeochemical and hydrological factors in affecting the spatial and temporal patterns of NO 3 - concentrations. The heterogeneous topography in the Adirondacks has generated diverse landscape features and patterns of connectivity that are especially important in regulating the temporal and spatial patterns of NO 3 - concentrations in surface waters

  20. Detection of Mucosal Recurrent Nasopharyngeal Carcinomas After Radiotherapy With Narrow-Band Imaging Endoscopy

    International Nuclear Information System (INIS)

    Wang, Wen-Hung; Lin, Yen-Chun; Chen, Wen-Cheng; Chen, Miao-Fen; Chen, Chih-Cheng; Lee, Kam-Fai

    2012-01-01

    Purpose: This study evaluated the feasibility of screening mucosal recurrent nasopharyngeal carcinoma with narrow-band imaging (NBI) endoscopy. Methods and Materials: One hundred and six patients were enrolled. All patients underwent conventional white-light (WL) endoscopic examination of the nasopharynx followed by NBI endoscopy. Biopsies were performed if recurrence was suspected. Results: We identified 32 suspected lesions by endoscopy in WL and/or NBI mode. Scattered brown spots (BS) were identified in 22 patients, and 4 of the 22 who had negative MRI findings were histopathologically confirmed to be neoplasias that were successfully removed via endoscopy. A comparison of the visualization in NBI closer view corresponded to histopathological findings in 22 BS, and the prevalence rates of neoplasias in tail signs, round signs, and irregularities signs were 0% (0/6), 0% (0/7), and 44.4% (4/9), respectively (p = 0.048). The sensitivity, specificity, and diagnostic capability were 37.5%, 92.9% and 0.652 for WL, 87.5%, 74.5% and 0.810 for NBI, and 87.5%, 87.8%, and 0.876 for NBI closer view, respectively. NBI closer view was effective in increasing specificity compared with NBI alone (87.8% vs. 74.5%, p < 0.05), and in increasing sensitivity and diagnostic capability compared to WL alone (87.5% vs. 37.5%, p < 0.05; 0.876 vs. 0.652, p = 0.0001). Conclusions: Although NBI in endoscopy can improve sensitivity of mucosal recurrent nasopharyngeal neoplasias, false-positive (nonneoplasia BS) results may be obtained in areas with nonspecific inflammatory changes due to postradiation effects. NBI closer view not only can offer a timely, convenient, and highly reliable assessment of mucosal recurrent nasopharyngeal carcinoma, it can also make endoscopic removal possible.

  1. Compensatory mechanisms activated with intermittent energy restriction: A randomized control trial.

    Science.gov (United States)

    Coutinho, Sílvia Ribeiro; Halset, Eline Holli; Gåsbakk, Sigrid; Rehfeld, Jens F; Kulseng, Bård; Truby, Helen; Martins, Cátia

    2018-06-01

    Strong compensatory responses, with reduced resting metabolic rate (RMR), increased exercise efficiency (ExEff) and appetite, are activated when weight loss (WL) is achieved with continuous energy restriction (CER), which try to restore energy balance. Intermittent energy restriction (IER), where short spells of energy restriction are interspaced by periods of habitual energy intake, may offer some protection in minimizing those responses. We aimed to compare the effect of IER versus CER on body composition and the compensatory responses induced by WL. 35 adults (age: 39 ± 9 y) with obesity (BMI: 36 ± 4 kg/m 2 ) were randomized to lose a similar weight with an IER (N = 18) or a CER (N = 17) diet over a 12 week period. Macronutrient composition and overall energy restriction (33% reduction) were similar between groups. Body weight/composition, RMR, fasting respiratory quotient (RQ), ExEff (10, 25, and 50 W), subjective appetite ratings (hunger, fullness, desire to eat, and prospective food consumption (PFC)), and appetite-regulating hormones (active ghrelin (AG), cholecystokinin (CCK), total peptide YY (PYY), active glucagon-like peptide-1 (GLP-1), and insulin) were measured before and after WL. Changes in body weight (≈12.5% WL) and composition were similar in both groups. Fasting RQ and ExEff at 10 W increased in both groups. Losing weight, either by IER or CER dieting, did not induce significant changes in subjective appetite ratings. RMR decreased and ExEff at 25 and 50 W increased (P intermittent, does not appear to modulate the compensatory mechanisms activated by weight loss. NCT02169778 (the study was registered in clinicaltrial.gov). Copyright © 2017 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

  2. 5-Aminoimidazole-4-carboxamide ribonucleotide prevents fat gain following the cessation of voluntary physical activity.

    Science.gov (United States)

    Ruegsegger, Gregory N; Sevage, Joseph A; Childs, Thomas E; Grigsby, Kolter B; Booth, Frank W

    2017-11-01

    What is the central question of this study? We investigated whether 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) could prevent acute increases in body fat and changes in omental and subcutaneous adipose tissue following the sudden transition from physical activity to physical inactivity. What is the main finding and its importance? AICAR prevented fat gains following the transition from physical activity to inactivity to levels comparable to rats that remained physically active. AICAR and continuous physical activity produced depot-specific changes in cyclin A1 mRNA and protein that were associated with the prevention of fat gain. These findings suggest that targeting AMP-activated protein kinase signalling could oppose rapid adipose mass growth. The transition from physical activity to inactivity is associated with drastic increases in 'catch-up' fat that in turn foster the development of many obesity-associated maladies. We tested whether 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) treatment would prevent gains in body fat following the sudden transition from a physically active state to an inactive state by locking a voluntary running wheel. Male Wistar rats were either sedentary (SED) or given wheel access for 4 weeks, at which time rats with wheels continued running (RUN), had their wheel locked (WL) or had WL with daily AICAR injection (WL + AICAR) for 1 week. RUN and WL + AICAR prevented gains in body fat compared with SED and WL (P RUN and WL + AICAR compared with SED and WL groups (P run, and that together, continuous physical activity and AICAR could, at least initially in these conditions, exert similar inhibitory effects on adipogenesis in a depot-specific manner. © 2017 The Authors. Experimental Physiology © 2017 The Physiological Society.

  3. Comparing the Efficacy of CBASP with Two Versions of CBT for Depression in a Routine Care Center: A Randomized Clinical Trial.

    Science.gov (United States)

    Rief, Winfried; Bleichhardt, Gabi; Dannehl, Katharina; Euteneuer, Frank; Wambach, Katrin

    2018-04-12

    The cognitive-behavioral analysis system of psychotherapy (CBASP) was developed for the treatment of chronic, early-onset depression. However, it is unclear whether this approach can be recommended for depression in general (episodic and chronic), and no direct comparisons between CBASP with different versions of cognitive-behavioral therapy (CBT) exist. A randomized controlled trial compared 3 treatment conditions (all lasting 16 sessions) with a waiting list group (WL): CBASP, CBT with a focus on physical exercise (CBT-E), and CBT with a focus on pleasurable, low-energy and mindful activities (CBT-M). We included 173 patients and involved 41 therapists. Assessments were at baseline, after session 8, and at the end of treatment. Our primary outcome Beck Depression Inventory-II indicated a general advantage of the CBT arms compared to CBASP [F(6, 154.5) = 4.2, p = 0.001], with significant contrasts in particular in favor of CBT-E. Effect sizes against WL were d = 0.91 (CBT-E), 0.87 (CBT-M), and 0.47 (CBASP). A triple interaction with an additional factor "chronic versus episodic depression" [F(6, 142.7) = 2.2, p = 0.048] indicated that the treatments resulted in different outcomes, with best results again for CBT-E in particular in episodic depression. Responder rates indicated significant improvements (56% in both CBT arms, 34% in the CBASP arm, 3.4% in WL; intention-to-treat samples). As compared to CBASP, response rates were significantly higher for CBT-E (OR = 2.48; 95% CI = 1.02-6.00) and CBT-M (OR = 2.46; 95% CI = 1.01-6.01). CBASP was more effective than WL, but less effective than the 2 CBT arms. This was mainly caused by an advantage of CBT interventions in episodic depression. © 2018 S. Karger AG, Basel.

  4. DEMONSTRATION SOLIDIFICATION TESTS CONDUCTED ON RADIOACTIVELY CONTAMINATED ORGANIC LIQUIDS AT THE AECL WHITESHELL LABORATORIES

    International Nuclear Information System (INIS)

    Ryz, R. A.; Brunkow, W. G.; Govers, R.; Campbell, D.; Krause, D.

    2002-01-01

    The AECL, Whiteshell Laboratory (WL) near Pinawa Manitoba, Canada, was established in the early 1960's to carry out AECL research and development activities for higher temperature versions of the CANDU(reg s ign) reactor. The initial focus of the research program was the Whiteshell Reactor-1 (WR-1) Organic Cooled Reactor (OCR) that began operation in 1965. The OCR program was discontinued in the early 1970's in favor of the successful heavy-water-cooled CANDU system. WR-1 continued to operate until 1985 in support of AECL nuclear research programs. A consequence of the Federal government's recent program review process was AECL's business decision to discontinue research programs and operations at the Whiteshell Laboratories and to consolidate its' activities at the Chalk River Laboratories. As a result, AECL received government concurrence in 1998 to proceed to plan actions to achieve closure of WL. The planning actions now in progress address the need to safely and effectively transition the WL site from an operational state, in support of AECL's business, to a shutdown and decommissioned state that meets the regulatory requirements for a licensed nuclear site. The decommissioning program that will be required at WL is unique within AECL and Canada since it will need to address the entire research site rather than individual facilities declared redundant. Accordingly, the site nuclear facilities are being systematically placed in a safe shutdown state and planning for the decommissioning work to place the facilities in a secure monitoring and surveillance state is in progress. One aspect of the shutdown activities is to deal with the legacy of radioactively contaminated organic liquid wastes. Use of a polymer powder to solidify these organic wastes was identified as one possibility for improved interim storage of this material pending final disposition

  5. Fourier transformation for engineering and natural science

    International Nuclear Information System (INIS)

    Klingen, B.

    2001-01-01

    The following topics are covered: functions, Dirac delta function, Fourier operators, Fourier integrals, Fourier transformation and periodic functions, discrete Fourier transformations and discrete filters, applications. (WL)

  6. Preschool Deployment of Evidence-Based Social Communication Intervention: JASPER in the Classroom.

    Science.gov (United States)

    Chang, Ya-Chih; Shire, Stephanie Y; Shih, Wendy; Gelfand, Carolyn; Kasari, Connie

    2016-06-01

    Few research-developed early intervention models have been deployed to and tested in real world preschool programs. In this study, teaching staff implemented a social communication modularized intervention, JASPER, in their daily program. Sixty-six preschool children with autism in twelve classrooms (12 teachers) were randomized to receive immediate JASPER training (IT) or were waitlisted (WL) for 3 months with a 1-month follow up. Measures of core deficits (initiations of joint engagement, joint attention gestures and language, play skills) and standardized cognitive measures were improved for IT over WL children. IT teachers achieved and maintained high fidelity. Teachers can implement evidence-based interventions with significant improvements in core deficits of their children with ASD.

  7. Report on investigation of remedial measures for the radiation reduction and radioactive decontamination of Elliot Lake, Ontario

    International Nuclear Information System (INIS)

    1981-02-01

    This is the fourth annual report on a program to monitor and reduce radon daughter exposures in the town of Elliot Lake, Ontario. Twelve month's WL survey measurements were completed in 1980 and showed that 22 houses exceeded the remedial action criterion of 0.02 WL. In a few cases gamma radiation levels were high enough to require remedial action in driveways and public areas, but not inside houses. During 1980 remedial work was carried out on 85 buildings; work was completed on 58. The most frequent routes of entry for radon and radon daughters were untrapped weeping tile connected to a floor drain or sump, and the wall to floor joint

  8. Optical properties of individual site-controlled Ge quantum dots

    Energy Technology Data Exchange (ETDEWEB)

    Grydlik, Martyna, E-mail: moritz.brehm@jku.at, E-mail: martyna.grydlik@jku.at [Institute of Semiconductor and Solid State Physics, Johannes Kepler University Linz, Altenbergerstrasse 69, 4040 Linz (Austria); Institute for Integrative Nanosciences, IFW Dresden, Helmholtzstr. 20, Dresden 01069 (Germany); Center for Advancing Electronics Dresden, CfAED, TU Dresden (Germany); Brehm, Moritz, E-mail: moritz.brehm@jku.at, E-mail: martyna.grydlik@jku.at [Institute of Semiconductor and Solid State Physics, Johannes Kepler University Linz, Altenbergerstrasse 69, 4040 Linz (Austria); Institute for Integrative Nanosciences, IFW Dresden, Helmholtzstr. 20, Dresden 01069 (Germany); Tayagaki, Takeshi [Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011 (Japan); Research Center for Photovoltaics, National Institute of Advanced Industrial Science and Technology, 1-1-1 Umezono, Tsukuba, Ibaraki 305-8568 (Japan); Langer, Gregor; Schäffler, Friedrich [Institute of Semiconductor and Solid State Physics, Johannes Kepler University Linz, Altenbergerstrasse 69, 4040 Linz (Austria); Schmidt, Oliver G. [Institute for Integrative Nanosciences, IFW Dresden, Helmholtzstr. 20, Dresden 01069 (Germany); Center for Advancing Electronics Dresden, CfAED, TU Dresden (Germany)

    2015-06-22

    We report photoluminescence (PL) experiments on individual SiGe quantum dots (QDs) that were epitaxially grown in a site-controlled fashion on pre-patterned Si(001) substrates. We demonstrate that the PL line-widths of single QDs decrease with excitation power to about 16 meV, a value that is much narrower than any of the previously reported PL signals in the SiGe/Si heterosystem. At low temperatures, the PL-intensity becomes limited by a 25 meV high potential-barrier between the QDs and the surrounding Ge wetting layer (WL). This barrier impedes QD filling from the WL which collects and traps most of the optically excited holes in this type-II heterosystem.

  9. A Comparison of Delayed Self-Heterodyne Interference Measurement of Laser Linewidth Using Mach-Zehnder and Michelson Interferometers

    Directory of Open Access Journals (Sweden)

    Simon Fleming

    2011-09-01

    Full Text Available Linewidth measurements of a distributed feedback (DFB fibre laser are made using delayed self heterodyne interferometry (DHSI with both Mach-Zehnder and Michelson interferometer configurations. Voigt fitting is used to extract and compare the Lorentzian and Gaussian linewidths and associated sources of noise. The respective measurements are wL (MZI = (1.6 ± 0.2 kHz and wL (MI = (1.4 ± 0.1 kHz. The Michelson with Faraday rotator mirrors gives a slightly narrower linewidth with significantly reduced error. This is explained by the unscrambling of polarisation drift using the Faraday rotator mirrors, confirmed by comparing with non-rotating standard gold coated fibre end mirrors.

  10. Resonance γ-ray polarimetry

    International Nuclear Information System (INIS)

    Gonser, U.; Fischer, H.

    1981-01-01

    The topics are: Intensity and polarization of radiation in Moessbauer transitions, hyperfine interactions in 57 Fe, polarized γ-rays, polarimetry, γ-ray rotation polarimeters, Birefringence polarimetry. (WL)

  11. Emotional clarity and attention to emotions in cognitive behavioral group therapy and mindfulness-based stress reduction for social anxiety disorder.

    Science.gov (United States)

    Butler, Rachel M; Boden, Matthew T; Olino, Thomas M; Morrison, Amanda S; Goldin, Philippe R; Gross, James J; Heimberg, Richard G

    2018-04-01

    We examined (1) differences between controls and patients with social anxiety disorder (SAD) in emotional clarity and attention to emotions; (2) changes in emotional clarity and attention to emotions associated with cognitive-behavioral group therapy (CBGT), mindfulness-based stress reduction (MBSR), or a waitlist (WL) condition; and (3) whether emotional clarity and attention to emotions moderated changes in social anxiety across treatment. Participants were healthy controls (n = 37) and patients with SAD (n = 108) who were assigned to CBGT, MBSR, or WL in a randomized controlled trial. At pretreatment, posttreatment, and 12-month follow-up, patients with SAD completed measures of social anxiety, emotional clarity, and attention to emotions. Controls completed measures at baseline only. At pretreatment, patients with SAD had lower levels of emotional clarity than controls. Emotional clarity increased significantly among patients receiving CBGT, and changes were maintained at 12-month follow-up. Emotional clarity at posttreatment did not differ between CBGT and MBSR or between MBSR and WL. Changes in emotional clarity predicted changes in social anxiety, but emotional clarity did not moderate treatment outcome. Analyses of attention to emotions were not significant. Implications for the role of emotional clarity in the treatment of SAD are discussed. Copyright © 2018 Elsevier Ltd. All rights reserved.

  12. Investigating cluster astrophysics and cosmology with cross-correlation of the thermal Sunyaev-Zel'dovich effect and weak lensing

    Science.gov (United States)

    Osato, Ken; Flender, Samuel; Nagai, Daisuke; Shirasaki, Masato; Yoshida, Naoki

    2018-03-01

    Recent detections of the cross-correlation of the thermal Sunyaev-Zel'dovich (tSZ) effect and weak gravitational lensing (WL) enable unique studies of cluster astrophysics and cosmology. In this work, we present constraints on the amplitude of the non-thermal pressure fraction in galaxy clusters, α0, and the amplitude of the matter power spectrum, σ8, using measurements of the tSZ power spectrum from Planck, and the tSZ-WL cross-correlation from Planck and the Red Cluster Sequence Lensing Survey. We fit the data to a semi-analytic model with the covariance matrix using N-body simulations. We find that the tSZ power spectrum alone prefers σ8 ˜ 0.85 and a large fraction of non-thermal pressure (α0 ˜ 0.2-0.3). The tSZ-WL cross-correlation on the other hand prefers a significantly lower σ8 ˜ 0.6 and low α0 ˜ 0.05. We show that this tension can be mitigated by allowing for a steep slope in the stellar mass-halo mass relation, which would cause a reduction of the gas in low-mass haloes. In such a model, the combined data prefer σ8 ˜ 0.7 and α0 ˜ 0.2, consistent with predictions from hydrodynamical simulations.

  13. The Child Anxiety Prevention Study: intervention model and primary outcomes.

    Science.gov (United States)

    Ginsburg, Golda S

    2009-06-01

    The article presents the intervention model and primary outcomes of a preventive intervention designed to reduce anxiety symptoms and prevent the onset of anxiety disorders in the offspring of parents with anxiety disorders. Participants were 40 volunteer children (mean age = 8.94 years; 45% girls; 90% Caucasian) whose parents met criteria for a broad range of anxiety disorders. Families were randomly assigned to an 8-week cognitive-behavioral intervention, the Coping and Promoting Strength program (CAPS; n = 20) or a wait list control condition (WL; n = 20). Independent evaluators (IEs) conducted diagnostic interviews, and children and parents completed measures of anxiety symptoms. Assessments were conducted pre- and postintervention and 6 and 12 months after the postintervention assessment. On the basis of intent to treat analyses, 30% of the children in the WL group developed an anxiety disorder by the 1-year follow-up compared with 0% in the CAPS group. IE and parent-reported (but not child-reported) levels of anxiety showed significant decreases from the preintervention assessment to the 1-year follow-up assessment in the CAPS but not the WL group. Parental satisfaction with the intervention was high. Findings suggest that a family-based intervention may prevent the onset of anxiety disorders in the offspring of parents with anxiety disorders. Copyright 2009 APA

  14. Robust bladder image registration by redefining data-term in total variational approach

    Science.gov (United States)

    Ali, Sharib; Daul, Christian; Galbrun, Ernest; Amouroux, Marine; Guillemin, François; Blondel, Walter

    2015-03-01

    Cystoscopy is the standard procedure for clinical diagnosis of bladder cancer diagnosis. Bladder carcinoma in situ are often multifocal and spread over large areas. In vivo, localization and follow-up of these tumors and their nearby sites is necessary. But, due to the small field of view (FOV) of the cystoscopic video images, urologists cannot easily interpret the scene. Bladder mosaicing using image registration facilitates this interpretation through the visualization of entire lesions with respect to anatomical landmarks. The reference white light (WL) modality is affected by a strong variability in terms of texture, illumination conditions and motion blur. Moreover, in the complementary fluorescence light (FL) modality, the texture is visually different from that of the WL. Existing algorithms were developed for a particular modality and scene conditions. This paper proposes a more general on fly image registration approach for dealing with these variability issues in cystoscopy. To do so, we present a novel, robust and accurate image registration scheme by redefining the data-term of the classical total variational (TV) approach. Quantitative results on realistic bladder phantom images are used for verifying accuracy and robustness of the proposed model. This method is also qualitatively assessed with patient data mosaicing for both WL and FL modalities.

  15. Nutrient changes and biodynamics of Eisenia fetida during vermicomposting of water lettuce (Pistia sp.) biomass: a noxious weed of aquatic system.

    Science.gov (United States)

    Suthar, Surindra; Pandey, Bhawna; Gusain, Rita; Gaur, Rubia Zahid; Kumar, Kapil

    2017-01-01

    This paper reports the results of vermicomposting of water lettuce biomass (WL) spiked with cow dung at ratios of 20, 40, 60, and 80 % employing Eisenia fetida. A total of four treatments were established and changes in chemical properties of mixtures were observed. Vermicomposting caused a decrease in pH, TOC, volatile solids, and C/N ratio by 1.01-1.08-fold, 0.85-0.92-fold, 0.94-0.96-fold, 0.56-0.70-fold, respectively, but increase in EC, tot N, tot P, tot K, tot Ca, tot Zn, tot Fe, and tot Cu, by 1.19-1.42-fold, 1.33-1.68-fold, 1.38-1.69-fold, 1.13-1.24-fold, 1.04-1.11-fold, 1.16-1.37-fold, 1.05-1.113-fold, 1.10-1.27-fold, respectively. Overall, the treatment with 60-80 % of WL showed the maximum decomposition and mineralization rates. The earthworm showed the growth and reproduction rate in considerable ranges in all treatment setups but setups with 60-80 % WL proportion exhibited the optimum results. Results reveal that biomass of water lettuce can be utilized effectively for production of valuable manure through vermicomposting system.

  16. Vitamin D supplementation during short-term caloric restriction in healthy overweight/obese older women: Effect on glycemic indices and serum osteocalcin levels.

    Science.gov (United States)

    Sukumar, D; Shapses, S A; Schneider, S H

    2015-07-15

    The effect of vitamin D supplementation and caloric restriction (CR) on glycemic indices and osteocalcin (OC) is not clear. In this randomized controlled double blind trial, we examined whether vitamin D3 supplementation at 2500 IU/d (D) or placebo has differential effects on markers of insulin sensitivity and bone turnover in overweight/obese postmenopausal women during 6 weeks of caloric restriction (weight loss; WL, n = 39) compared to weight maintenance (WM, n = 37). Seventy-six women (57 ± 6 years) completed this study and the WL groups lost 4 ± 1% of body weight. Baseline serum 25-hydroxyvitamin D (25OHD) was 24.8 ± 5.6 ng/mL at baseline; the rise was greatest in WL-D group (p < 0.05). There was an interaction between vitamin D intake and weight on serum OC, insulin, glucose and markers of insulin sensitivity (p < 0.05). The change in OC was explained by changes in serum 25OHD and insulin (model R(2) = 25.6%). Overall, vitamin D supplementation and CR influence serum osteocalcin levels and modestly favor improvements in insulin sensitivity. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  17. Protein-pacing caloric-restriction enhances body composition similarly in obese men and women during weight loss and sustains efficacy during long-term weight maintenance

    DEFF Research Database (Denmark)

    Arciero, Paul J; Edmonds, Rohan; He, Feng

    2016-01-01

    Short-Term protein-pacing (P; ~6 meals/day, >30% protein/day) and caloric restriction (CR, ~25% energy deficit) improves total (TBF), abdominal (ABF) and visceral (VAT) fat loss, energy expenditure, and biomarkers compared to heart healthy (HH) recommendations (3 meals/day, 15% protein/day) in ob......Short-Term protein-pacing (P; ~6 meals/day, >30% protein/day) and caloric restriction (CR, ~25% energy deficit) improves total (TBF), abdominal (ABF) and visceral (VAT) fat loss, energy expenditure, and biomarkers compared to heart healthy (HH) recommendations (3 meals/day, 15% protein....../day) in obese adults. Less is known whether obese men and women respond similarly to P-CR during weight loss (WL) and whether a modified P-CR (mP-CR) is more efficacious than a HH diet during long-term (52 week) weight maintenance (WM). The purposes of this study were to evaluate the efficacy of: (1) P......-CR on TBF, ABF, resting metabolic rate (RMR), and biomarkers between obese men and women during WL (weeks 0-12); and (2) mP-CR compared to a HH diet during WM (weeks 13-64). During WL, men (n = 21) and women (n = 19) were assessed for TBF, ABF, VAT, RMR, and biomarkers at weeks 0 (pre) and 12 (post). Men...

  18. Wetting layers effect on InAs/GaAs quantum dots

    International Nuclear Information System (INIS)

    Sun Chao; Lu Pengfei; Yu Zhongyuan; Cao Huawei; Zhang Lidong

    2012-01-01

    FEM combining with the K·P theory is adopted to systematically investigate the effect of wetting layers on the strain-stress profiles and electronic structures of self-organized InAs quantum dot. Four different kinds of quantum dots are introduced at the same height and aspect ratio. We found that 0.5 nm wetting layer is an appropriate thickness for InAs/GaAs quantum dots. Strain shift down about 3%∼4.5% for the cases with WL (0.5 nm) and without WL in four shapes of quantum dots. For band edge energy, wetting layers expand the potential energy gap width. When WL thickness is more than 0.8 nm, the band edge energy profiles cannot vary regularly. The electron energy is affected while for heavy hole this impact on the energy is limited. Wetting layers for the influence of the electronic structure is obviously than the heavy hole. Consequently, the electron probability density function spread from buffer to wetting layer while the center of hole's function moves from QDs internal to wetting layer when introduce WLs. When WLs thickness is larger than 0.8 nm, the electronic structures of quantum dots have changed obviously. This will affect the instrument's performance which relies on the quantum dots' optical properties.

  19. Damage and repair in mammalian cells after ultraviolet and/or visible light treatment

    International Nuclear Information System (INIS)

    Harm, H.

    1976-01-01

    Ultraviolet (uv) light (254 nm or 302 nm) was used to induce lesions in DNA of cultured mammalian cells in vivo, particularly in fibroblasts from potoroo cornea, mouse skin (3T3), cat cornea, human skin (healthy and diseased), and in freshly obtained ox cornea tissue. In addition, white light (WL) from daylight fluorescent lamps, filtered through a plexiglass plate cutting off virtually all photons less than 380 nm and being fully transparent for greater than 400 nm, was applied in vivo either as photoreactivating light after uv irradiation, or as damaging radiation by itself. Completely unirradiated samples under otherwise identical conditions served as controls. DNA from cells exposed to these different radiations was extracted and tested for its capability of competitively inhibiting photoenzymatic repair of uv-irradiated Haemophilus influenzae transforming DNA in vitro in the presence of yeast photoreactivating enzyme (PRE) and photoreactivating light. In several (but not all) of the cases, DNA from cells treated with uv + WL displayed considerably less competitive inhibition than DNA from cells treated with uv alone, even though under certain conditions WL itself caused damage serving as substrate from the PRE in vitro. Cell cultures differing in their origin or in their number of passages varied substantially in this respect

  20. Protein supplements after weight loss do not improve weight maintenance compared with recommended dietary protein intake despite beneficial effects on appetite sensation and energy expenditure: a randomized, controlled, double-blinded trial.

    Science.gov (United States)

    Kjølbæk, Louise; Sørensen, Lone Brinkmann; Søndertoft, Nadja Buus; Rasmussen, Carrie Klestrup; Lorenzen, Janne Kunchel; Serena, Anja; Astrup, Arne; Larsen, Lesli Hingstrup

    2017-08-01

    Background : High-protein diets increase weight loss (WL) during energy restriction; therefore, it has been suggested that additional protein intake may improve weight maintenance (WM) after WL. Objective: We investigated the effect of protein supplements from either whey with or without calcium or soy on WM success after WL compared with that of a control. Design: In a randomized, controlled, double-blinded trial, 220 participants aged 18-60 y with body mass index (in kg/m 2 ) from 27.6 to 40.4 were included. The study was initiated with an 8-wk WL period followed by a 24-wk WM period. During WM, participants consumed the following isocaloric supplements (45-48 g/d): whey and calcium (whey+), whey, soy, or maltodextrin (control). Data were collected at baseline, before WM, and after WM (weeks 0, 8, and 32, respectively) and included body composition, blood biochemistry, and blood pressure. Meal tests were performed to investigate diet-induced-thermogenesis (DIT) and appetite sensation. Compliance was tested by 24-h urinary nitrogen excretion. Results: A total of 151 participants completed the WM period. The control and 3 protein supplements did not result in different mean ± SD weight regains (whey+: 2.19 ± 4.6 kg; whey: 2.01 ± 4.6 kg; soy: 1.76 ± 4.7 kg; and control: 2.23 ± 3.8 kg; P = 0.96), fat mass regains (whey+: 0.46 ± 4.5 kg; whey: 0.11 ± 4.1 kg; soy: 0.15 ± 4.1 kg; and control: 0.54 ± 3.3 kg; P = 0.96), or improvements in lean body mass (whey+: 1.87 ± 1.7 kg; whey: 1.94 ± 1.3 kg; soy: 1.58 ± 1.4 kg; and control: 1.74 ± 1.4 kg; P = 0.50) during WM. Changes in blood pressure and blood biochemistry were not different between groups. Compared with the control, protein supplementation resulted in higher DIT (∼30 kJ/2.5 h) and resting energy expenditure (243 kJ/d) and an anorexigenic appetite-sensation profile. Conclusion: Protein supplementation does not result in improved WM success, or blood biochemistry after WL compared with the effects of

  1. Litter quality and its response to water level drawdown in boreal peatlands at plant species and community level

    Science.gov (United States)

    Straková, Petra; Anttila, Jani; Spetz, Peter; Kitunen, Veikko; Tapanila, Tarja; Laiho, Raija

    2010-05-01

    There is increasing evidence that changes in the species composition and structure of plant communities induced by global change will have much more impact on plant-mediated carbon cycling than any phenotypic responses. These impacts are largely mediated by shifts in litter quality. There are few documentations of these changes so far, due to the relatively long time scale required for their direct observation. Here, we examine the changes in litter inputs induced by persistent water-level drawdown in boreal peatland sites. Peatlands contain a major proportion of the terrestrial carbon pool, and it is thus important to be able to predict their behaviour and role in the global C cycle under different global change factors. We studied the effects of short-term (ca. 4 years) and long-term (ca. 40 years) persistent water level (WL) drawdown on the quantity and chemical quality of above-ground plant litter inputs at three sites: bog, oligotrophic fen and mesotrophic fen. The parameters used to characterize litter quality included various extractable substances, cellulose, holocellulose, composition of hemicellulose (neutral sugars, uronic acids), lignin, CuO oxidation phenolic products, and concentrations of C, nitrogen (N), phosphorus (P), potassium, magnesium, manganese and calcium. Four different groups of litter were clearly distinct based on their chemical quality: foliar litters, graminoids, mosses and woody litters. The pristine conditions were characterized by Sphagnum moss and graminoid litter. Following short-term WL drawdown, changes in the quality and quantity of litter inputs were small. Following long-term WL drawdown, total litter inputs dramatically increased, due to increased tree litter inputs, and the litter type composition greatly changed. These changes resulted in annual inputs of 1901-2010 kg•ha-1 C, 22-24 kg•ha-1 N, 1.5-2.2 kg•ha-1 P, 967-1235 kg•ha-1 lignin and lignin-like compounds and 254-300 kg•ha-1 water solubles after long-term WL

  2. Translation vs. Rotation: The Battle for Accommodation of Dextral Shear at the Northern Terminus of the Central Walker Lane, Western Nevada

    Science.gov (United States)

    Carlson, C. W.; Faulds, J. E.

    2014-12-01

    Positioned between the Sierra Nevada microplate and Basin and Range in western North America, the Walker Lane (WL) accommodates ~20% of the dextral motion between the North American and Pacific plates on predominately NW-striking dextral and ENE to E-W-striking sinistral fault systems. The Terrill Mountains (TM) lie at the northern terminus of a domain of dextral faults accommodating translation of crustal-blocks in the central WL and at the southeast edge of sinistral faults accommodating oroclinal flexure and CW rotation of blocks in the northern WL. As the mechanisms of strain transfer between these disparate fault systems are poorly understood, the thick Oligocene to Pliocene volcanic strata of the TM area make it an ideal site for studying the transfer of strain between regions undergoing differing styles of deformation and yet both accommodating dextral shear. Detailed geologic mapping and paleomagnetic study of ash-flow tuffs in the TM region has been conducted to elucidate Neogene strain accommodation for this transitional region of the WL. Strain at the northernmost TM appears to be transferred from a system of NW-striking dextral faults to a system of ~E-W striking sinistral faults with associated CW flexure. A distinct ~23 Ma paleosol is locally preserved below the tuff of Toiyabe and provides an important marker bed. This paleosol is offset with ~6 km of dextral separation across the fault bounding the NE flank of the TM. This fault is inferred as the northernmost strand of the NW-striking, dextral Benton Spring fault system, with offset consistent with minimums constrained to the south (6.4-9.6 km, Gabbs Valley Range). Paleomagnetic results suggest counter-intuitive CCW vertical-axis rotation of crustal blocks south of the domain boundary in the system of NW-striking dextral faults, similar to some other domains of NW-striking dextral faults in the northern WL. This may result from coeval dextral shear and WNW-directed extension within the left

  3. Efficacy of Cognitive Behavioral Therapy for Insomnia in Adolescents: A Randomized Controlled Trial with Internet Therapy, Group Therapy and A Waiting List Condition.

    Science.gov (United States)

    de Bruin, Eduard J; Bögels, Susan M; Oort, Frans J; Meijer, Anne Marie

    2015-12-01

    To investigate the efficacy of cognitive behavioral therapy for insomnia (CBTI) in adolescents. A randomized controlled trial of CBTI in group therapy (GT), guided internet therapy (IT), and a waiting list (WL), with assessments at baseline, directly after treatment (post-test), and at 2 months follow-up. Diagnostic interviews were held at the laboratory of the Research Institute of Child Development and Education at the University of Amsterdam. Treatment for GT occurred at the mental health care center UvAMinds in Amsterdam, the Netherlands. One hundred sixteen adolescents (mean age = 15.6 y, SD = 1.6 y, 25% males) meeting DSM-IV criteria for insomnia, were randomized to IT, GT, or WL. CBTI of 6 weekly sessions, consisted of psychoeducation, sleep hygiene, restriction of time in bed, stimulus control, cognitive therapy, and relaxation techniques. GT was conducted in groups of 6 to 8 adolescents, guided by 2 trained sleep therapists. IT was applied through an online guided self-help website with programmed instructions and written feedback from a trained sleep therapist. Sleep was measured with actigraphy and sleep logs for 7 consecutive days. Symptoms of insomnia and chronic sleep reduction were measured with questionnaires. Results showed that adolescents in both IT and GT, compared to WL, improved significantly on sleep efficiency, sleep onset latency, wake after sleep onset, and total sleep time at post-test, and improvements were maintained at follow-up. Most of these improvements were found in both objective and subjective measures. Furthermore, insomnia complaints and symptoms of chronic sleep reduction also decreased significantly in both treatment conditions compared to WL. Effect sizes for improvements ranged from medium to large. A greater proportion of participants from the treatment conditions showed high end-state functioning and clinically significant improvement after treatment and at follow-up compared to WL. This study is the first randomized

  4. New results from SPEAR

    International Nuclear Information System (INIS)

    Sadrozinski, H.F.W.

    1977-01-01

    This article is devided into the following headings: Charmonium spectroscopy, charm spectroscopy, threshold effects in charm search, heavy lepton search and scaling in inclusive hadron production. (WL) [de

  5. non -governmental organisations' response to substance abuse

    African Journals Online (AJOL)

    User

    National Association of Social Workers-Zimbabwe/Author(s) ... The paper adopted qualitative research methodology and street ethnography approach. ..... W.L. (2011) Social Research Methods, Qualitative and Quantitative Approaches.

  6. Secretary Marshall's Employment Strategies

    Science.gov (United States)

    Stevenson, Gloria

    1977-01-01

    A review of proposed employment strategies and priorities of Ray Marshall, Secretary of Labor, with regard to training programs, governmental subsidy programs, apprenticeships, private sector jobs, etc. (WL)

  7. Dissipative phenomena in deep inelastic heavy ion collisions

    International Nuclear Information System (INIS)

    Gross, D.H.E.; Krappe, H.J.; Lindenberger, K.H.; Lipperheide, R.; Moehring, K.

    1978-01-01

    During this meeting the following theoretical concepts for deep-inelastic heavy ion reactions were discussed: the energy transfer and friction, direct or statistical mechanisms, dissipation and fluctuation. (WL) [de

  8. On the evolution of InAs thin films grown by molecular beam epitaxy on the GaAs(001) surface

    International Nuclear Information System (INIS)

    Grabowski, Jan

    2010-01-01

    Semiconductor nanostructures are currently of high interest for a wide variety of electronic and optoelectronic applications. A large number of devices, in particular for the optical data transmission in the long-wavelength range, essential in modern communication, are based on InAs/GaAs quantum dot (QD) structures. Though the properties of the InAs/GaAs QDs have been extensively studied, only little is known about the formation and structure of the wetting layer (WL) yet. In the present work, the pathway of the InAs WL evolution is studied in detail. For this purpose, InAs thin films in the range of one monolayer (ML) are deposited on the GaAs(001) surface by molecular beam epitaxy (MBE) and studied by reflection high energy electron diffraction (RHEED) and in particular by scanning tunneling microscopy (STM). The InAs thin films are grown in both typical growth regimes, on the GaAs-c(4 x 4) and the GaAs-β2(2 x 4) reconstructed surface, in a variety of thicknesses starting from submonolayers with 0.09 ML of InAs up to 1.65 ML of InAs exceeding the critical thickness for QD growth. In principle, three growth stages are found. At low InAs coverages, the indium adsorbs in agglomerations of typically eight In atoms at energetically preferable surface sites. In the STM images, the signatures of these In agglomerations appear with a clear bright contrast. A structural model for the initial formation of these signatures is presented, and its electronic and strain related properties are discussed. At an InAs coverage of about 0.67ML the initial surface transforms into a (4 x 3) reconstructed In 2/3 Ga 1/3 As ML and the detailed structure and strain properties of this surface are unraveled. On top of the InGaAs ML further deposited InAs forms a second layer, characterized by a typical zig-zag alignment of (2 x 4) reconstructed unit cells, with an alternating α2/α2-m configuration. In contrast to the previous surface reconstructions, where structural strain is

  9. On the evolution of InAs thin films grown by molecular beam epitaxy on the GaAs(001) surface

    Energy Technology Data Exchange (ETDEWEB)

    Grabowski, Jan

    2010-12-14

    Semiconductor nanostructures are currently of high interest for a wide variety of electronic and optoelectronic applications. A large number of devices, in particular for the optical data transmission in the long-wavelength range, essential in modern communication, are based on InAs/GaAs quantum dot (QD) structures. Though the properties of the InAs/GaAs QDs have been extensively studied, only little is known about the formation and structure of the wetting layer (WL) yet. In the present work, the pathway of the InAs WL evolution is studied in detail. For this purpose, InAs thin films in the range of one monolayer (ML) are deposited on the GaAs(001) surface by molecular beam epitaxy (MBE) and studied by reflection high energy electron diffraction (RHEED) and in particular by scanning tunneling microscopy (STM). The InAs thin films are grown in both typical growth regimes, on the GaAs-c(4 x 4) and the GaAs-{beta}2(2 x 4) reconstructed surface, in a variety of thicknesses starting from submonolayers with 0.09 ML of InAs up to 1.65 ML of InAs exceeding the critical thickness for QD growth. In principle, three growth stages are found. At low InAs coverages, the indium adsorbs in agglomerations of typically eight In atoms at energetically preferable surface sites. In the STM images, the signatures of these In agglomerations appear with a clear bright contrast. A structural model for the initial formation of these signatures is presented, and its electronic and strain related properties are discussed. At an InAs coverage of about 0.67ML the initial surface transforms into a (4 x 3) reconstructed In{sub 2/3}Ga{sub 1/3}As ML and the detailed structure and strain properties of this surface are unraveled. On top of the InGaAs ML further deposited InAs forms a second layer, characterized by a typical zig-zag alignment of (2 x 4) reconstructed unit cells, with an alternating {alpha}2/{alpha}2-m configuration. In contrast to the previous surface reconstructions, where

  10. Colchicum genus in the writings of ancient Greek and Byzantine physicians.

    Science.gov (United States)

    Tsoucalas, Gregory; Papaioannou, Theodoros; Panayiotakopoulos, George; Saridaki, Zenia; Vrachatis, Dimitrios A; Karamanou, Marianna

    2018-01-14

    The plants of the Colchicum family were known during the archaic period in Greece for their deleterious properties. Later on, they were used for the treatment of podagra. The treatment was introduced by the ancient Greek physicians and passed on to the Byzantine and Arabian physicians to endure until nowadays. The first plant was most probably named "Medea" from the notorious Colchican witch. As the most common member of the family blossoms in autumn, the plant was named Colchicum autumnale. Various nominations were also used, such as Ephemeron, Hermodactyl, Anima articulorum and Surugen. Our article discusses them, while at the same time presents the most notable authorities who have used Colchicum plants in herbal medicine and toxicology. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  11. Who is in control?

    DEFF Research Database (Denmark)

    Busck, Ole Gunni; Knudsen, Herman; Lind, Jens

    in a selection of Danish companies. The main hypothesis, based on fifty years of solid international research, assuming a positive effect of employee’s participation in decisions regarding their job and their work place was confirmed. However, the secondary hypothesis, based on recent research into participative......This paper presents the results of the MEDEA project financed by the Danish Work Environment Foundation and finalised October 2009. The project empirically investigated the significance of employee participation in all its direct and representative forms for the quality of the work environment...... work organisation and the fact that psychosocial problems at work in many countries have increased concomitantly with such organisation, assuming that in certain contexts and forms participation influences negatively on the work environment also found some support. Results showed that participative...

  12. W7-AS/W7-X contributions to the 20th European conference on controlled fusion and plasma heating

    International Nuclear Information System (INIS)

    1993-08-01

    This report contains the 23 contributions of the Max-Planck-Institut fuer Plasmaphysik to the above mentioned conference. The contributions deal with plasma heating problems in the Wendelstein stellarators. (WL)

  13. Twelve-month follow-up of virtual reality and standard exposure therapies for the fear of flying.

    Science.gov (United States)

    Rothbaum, Barbara Olasov; Hodges, Larry; Anderson, Page L; Price, Larry; Smith, Samantha

    2002-04-01

    This study reports the 12-month follow-up from patients with the fear of flying who were treated in a controlled study and randomly assigned (n = 49) to virtual reality exposure (VRE) therapy, standard exposure (SE) therapy, or to a wait-list control (WL). VRE and SE were equally superior to WL. At 12 months posttreatment, data were gathered on 24 of the 30 (80%) patients who were assigned to VRE or SE. Patients maintained their treatment gains, and 92% of VRE participants and 91% of SE participants had flown on a real airplane since the graduation flight. This is the 1st year-long follow-up of patients having been treated with VRE and indicates that short-term treatment can have lasting effects.

  14. Generalization of the Wide-Sense Markov Concept to a Widely Linear Processing

    International Nuclear Information System (INIS)

    Espinosa-Pulido, Juan Antonio; Navarro-Moreno, Jesús; Fernández-Alcalá, Rosa María; Ruiz-Molina, Juan Carlos; Oya-Lechuga, Antonia; Ruiz-Fuentes, Nuria

    2014-01-01

    In this paper we show that the classical definition and the associated characterizations of wide-sense Markov (WSM) signals are not valid for improper complex signals. For that, we propose an extension of the concept of WSM to a widely linear (WL) setting and the study of new characterizations. Specifically, we introduce a new class of signals, called widely linear Markov (WLM) signals, and we analyze some of their properties based either on second-order properties or on state-space models from a WL processing standpoint. The study is performed in both the forwards and backwards directions of time. Thus, we provide two forwards and backwards Markovian representations for WLM signals. Finally, different estimation recursive algorithms are obtained for these models

  15. Nuclear astrophysics of the sun

    International Nuclear Information System (INIS)

    Kocharov, G.E.

    1980-01-01

    In the first chapter we will discuss the problem of nuclear reactions in the interior of the sun and consider the modern aspects of the neutrino astrophysics of the Sun. The second chapter is devoted to the high energy interactions in the solar atmosphere during the flares. Among a great number of events during the solar flares we shall consider mainly the nuclear reactions. Special attention will be paid to the genetic connection between the different components of solar electromagnetic and corpuscular radiation. The idea of the unity of processes in different parts of the Sun, from hot and dense interior up to the rare plasma of the solar corona will be the main line of the book. (orig./WL) 891 WL/orig.- 892 HIS

  16. Can atrophic-erosive oral lichen planus promote cardiovascular diseases? A population-based study.

    Science.gov (United States)

    Conrotto, D; Barattero, R; Carbone, M; Gambino, A; Sciannameo, V; Ricceri, F; Conrotto, F; Broccoletti, R; Arduino, P-G

    2018-03-01

    Lichen planus has been recently associated with an increased risk of cardiovascular diseases (CVDs). The oral manifestations can be divided into white hyperkeratotic lesions (WL) and atrophic and erosive lesions (RL). The aim of this report was to compare the presence of CVDs between patients affected by WL or RL, to test the hypothesis that RL are associated with an increased incidence of CVDs. Patients were analysed through a complete collection of all the risk factors for CVDs. The primary endpoint was the occurrence of a cardiovascular event-acute coronary syndrome (ACS), any revascularization or stroke/TIA. A multivariable logistic regression model, adjusted for age at diagnosis, body mass index, smoking, alcohol consumption, diabetes, hypertension, CVDs familiarity and periodontitis, was performed. A prospective cohort of 307 patients has been evaluated; 185 (60.3%) had WL and 122 RL (39.7%). Twenty-four patients had a CVD. ACS occurred more frequently in RL (adjusted odds ratio 5.83; 95% CI: 1.16-29.39), mainly due to the higher risk of it after the histological diagnosis of Oral lichen planus OLP (odds ratio 4.23; 95% CI: 0.66-27.23). Patients with RL could possibly have a higher risk of developing ACS. Further analysis on larger cohort is however warranted. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. All rights reserved.

  17. Green Care Farms

    Directory of Open Access Journals (Sweden)

    Simone R. de Bruin PhD

    2015-10-01

    Full Text Available Objective: To explore the value of day services at green care farms (GCFs in terms of social participation for people with dementia. Method: Semi-structured interviews were conducted with people with dementia who attended day services at a GCF (GCF group, n = 21, were on a waiting list (WL for day services at a GCF (WL group, n = 12, or attended day services in a regular day care facility (RDCF group, n = 17 and with their family caregivers. Results: People with dementia in the GCF and WL group were primarily males, with an average age of 71 and 76 years, respectively, who almost all had a spousal caregiver. People with dementia in the RDCF group were mostly females with an average age of 85 years, most of whom had a non-spousal caregiver. For both the GCF and RDCF groups, it was indicated that day services made people with dementia feel part of society. The most important domains of social participation addressed by RDCFs were social interactions and recreational activities. GCFs additionally addressed the domains “paid employment” and “volunteer work.” Conclusion: GCFs are valuable in terms of social participation for a particular group of people with dementia. Matching characteristics of adult day services (ADS centers to the preferences and capacities of people with dementia is of importance. Diversity in ADS centers is therefore desirable.

  18. Acclimation of Haslea ostrearia to light of different spectral qualities - confirmation of 'chromatic adaptation' in diatoms.

    Science.gov (United States)

    Mouget, Jean-Luc; Rosa, Philippe; Tremblin, Gérard

    2004-07-19

    The marine diatom Haslea ostrearia was cultured under light of different qualities, white (WL), blue (BL), green (GL), yellow (YL), red (RL), and far-red (FRL) and at two irradiance levels, low and high (20 and 100 micromolphotonsm(-2)s(-1), respectively). The effects of the different light regimes were studied on growth, pigment content, and photosynthesis, estimated by the modulated fluorescence of chlorophyll, as relative electron transport rate (rETR). For all the light qualities studied, growth rates were higher at high irradiance. Compared to the corresponding WL controls, growth was higher in BL and lower in YL at low irradiance, and lower in YL and GL at high irradiance. Except for YL, almost all the pigment contents of the cells were lower at high irradiance. At low irradiance, cell pigment contents (chlorophyll a and c, fucoxanthin) and pigment ratios (in function of chlorophyll a) were lower in YL, RL, and FRL. Whatever the irradiance level, the maximum PSII quantum efficiency (F(v)/F(m) remained almost constant for WL, BL, and GL. Other fluorescence parameters (photochemical quenching, rETR(max), and alpha, the maximum light utilization coefficient) were lower in GL, YL, RL, and FRL, at low irradiance. Although not statistically significant, BL caused an increase in these fluorescence parameters. These findings are interpreted as evidence that inverse chromatic acclimation occurs in diatoms.

  19. Examining Mediators and Moderators of Yoga for Women With Breast Cancer Undergoing Radiotherapy.

    Science.gov (United States)

    Ratcliff, Chelsea G; Milbury, Kathrin; Chandwani, Kavita D; Chaoul, Alejandro; Perkins, George; Nagarathna, Raghuram; Haddad, Robin; Nagendra, Hongasandra Ramarao; Raghuram, N V; Spelman, Amy; Arun, Banu; Wei, Qi; Cohen, Lorenzo

    2016-09-01

    Hypothesis This study examines moderators and mediators of a yoga intervention targeting quality-of-life (QOL) outcomes in women with breast cancer receiving radiotherapy.Methods Women undergoing 6 weeks of radiotherapy were randomized to a yoga (YG; n = 53) or stretching (ST; n = 56) intervention or a waitlist control group (WL; n = 54). Depressive symptoms and sleep disturbances were measured at baseline. Mediator (posttraumatic stress symptoms, benefit finding, and cortisol slope) and outcome (36-item Short Form [SF]-36 mental and physical component scales [MCS and PCS]) variables were assessed at baseline, end-of-treatment, and 1-, 3-, and 6-months posttreatment. Results Baseline depressive symptoms (P = .03) and sleep disturbances (P moderated the Group × Time effect on MCS, but not PCS. Women with high baseline depressive symptoms in YG reported marginally higher 3-month MCS than their counterparts in WL (P = .11). Women with high baseline sleep disturbances in YG reported higher 3-months MCS than their counterparts in WL (P mediated the effect of YG on 6-month PCS. Posttraumatic stress symptoms and cortisol slope did not mediate treatment effect on QOL. Conclusion Yoga may provide the greatest mental-health-related QOL benefits for those experiencing pre-radiotherapy sleep disturbance and depressive symptoms. Yoga may improve physical-health-related QOL by increasing ability to find benefit in the cancer experience. © The Author(s) 2016.

  20. Relationship of radioactive radon daughters and cigarette smoking in the genesis of lung cancer in uranium miners

    International Nuclear Information System (INIS)

    Saccomanno, G.; Huth, G.C.; Auerbach, O.; Kuschner, M.

    1988-01-01

    This article documents the study of 383 cases of lung cancer in uranium miners and presents for the first time the relationship of radioactive radon gas and cigarette smoking. There is evidence that alpha radiation from radon gas at exposure levels above 465 working level months (WLM) is a strong contributor to the development of lung cancer. Cigarette smoking plays the most significant role in causing lung tumor; this is also noticed in nonminers who smoke cigarettes. A synergistic or additive effect of these two carcinogens is strongly suggested. The data indicate that small cell tumors develop in younger nonsmoking miners exposed to radon levels above 465 WLM. Lung cancers develop in smoking miners at lower levels of radon exposure than in nonsmoking miners. Based on an average mining experience of 15 years, there is substantial evidence that the present maximum allowable limit of 0.3 working levels (WL), or 4 working level months (WLM) per year, is safe, representing a margin of safety of approximately 10:1. Furthermore, a comparison of these data with the radon levels in some homes, averaging in the neighborhood of 0.025 WL, would indicate that health risks at these levels are negligible. It is suggested that 20 picocuries/liter, which equals 0.10 WL, be the maximum allowable level in homes

  1. Canal shaping with WaveOne Primary reciprocating files and ProTaper system: a comparative study.

    Science.gov (United States)

    Berutti, Elio; Chiandussi, Giorgio; Paolino, Davide Salvatore; Scotti, Nicola; Cantatore, Giuseppe; Castellucci, Arnaldo; Pasqualini, Damiano

    2012-04-01

    This study compared the canal curvature and axis modification after instrumentation with WaveOne Primary reciprocating files (Dentsply Maillefer, Ballaigues, Switzerland) and nickel-titanium (NiTi) rotary ProTaper (Dentsply Maillefer). Thirty ISO 15, 0.02 taper, Endo Training Blocks (Dentsply Maillefer) were used. In all specimens, the glide path was achieved with PathFile 1, 2, and 3 (Dentsply Maillefer) at the working length (WL). Specimens were then assigned to 1 of 2 groups for shaping: specimens in group 1 were shaped with ProTaper S1-S2-F1-F2 at the WL and specimens in group 2 were shaped with WaveOne Primary reciprocating files at the WL. Pre- and postinstrumentation digital images were superimposed and processed with Matlab r2010b (The MathWorks Inc, Natick, MA) software to analyze the curvature-radius ratio (CRr) and the relative axis error (rAe), representing canal curvature modification. Data were analyzed with one-way balanced analyses of variance at 2 levels (P < .05). The instrument factor was extremely significant for both the CRr parameter (F(1) = 9.59, P = .004) and the rAe parameter (F(1) = 13.55, P = .001). Canal modifications are reduced when the new WaveOne NiTi single-file system is used. Copyright © 2012 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  2. The radiological impact of the Ranger Uranium Mine on the general public in Jabiru

    International Nuclear Information System (INIS)

    Kavasnicka, Jiri

    1992-01-01

    Potential alpha energy concentrations (PAEC) of radon daughters were monitored by a Kodak LR 115 nuclear track detector both outdoors and indoors in Jabiru (a township 9 km west of the Ranger Uranium Mine) at five locations between Ranger and Jabiru during the 1989 Dry Season. The average outdoor PAEC and the indoor PAEC in private dwellings in Jabiru were 2.4 ± 0.2 mWL and 2.4 ± 0.7 mWL respectively. Though the total radon emission from the Ranger Uranium Mine (RUM) project is relatively high (about 7 MBq s -1 ) the mining and milling of uranium contributes only marginally to the PAEC in Jabiru as can be seen from results of the air dispersion modelling and environmental radon daughter monitoring carried out in parallel with the indoor monitoring in Jabiru. The description of the radon daughter monitor and the major characteristics of the RUM project are given in the Appendixes. The average annual PAEC in Jabiru attributable t the mining and milling operations at Ranger was calculated to be about 0.16 mWL, which corresponds to an effective dose equivalent of 0.07 mSv y -1 (7% of the 1 mSv y -1 public limit) for members of the public in Jabiru. 17 refs., 3 tab., 7 figs

  3. Preliminary Findings that a Targeted Intervention Leads to Altered Brain Function in Children with Fetal Alcohol Spectrum Disorder

    Directory of Open Access Journals (Sweden)

    Kelly Nash

    2017-12-01

    Full Text Available Children with fetal alcohol spectrum disorder (FASD exhibit behavioral dysregulation, executive dysfunction, and atypical function in associated brain regions. Previous research shows early intervention mitigates these outcomes but corresponding brain changes were not studied. Given the Alert® Program for Self-Regulation improves behavioral regulation and executive function in children with FASD, we asked if this therapy also improves their neural functioning in associated regions. Twenty-one children with FASD aged 8–12 years were randomized to the Alert®-treatment (TXT; n = 10 or waitlist-control (WL; n = 11 conditions. They were assessed with a Go-NoGo functional magnetic resonance imaging (fMRI paradigm before and after training or the wait-out period. Groups initially performed equivalently and showed no fMRI differences. At post-test, TXT outperformed WL on NoGo trials while fMRI in uncorrected results with a small-volume correction showed less activation in prefrontal, temporal, and cingulate regions. Groups also demonstrated different patterns of change over time reflecting reduced signal at post-test in selective prefrontal and parietal regions in TXT and increased in WL. In light of previous evidence indicating TXT at post-test perform similar to non-exposed children on the Go-NoGo fMRI paradigm, our findings suggest Alert® does improve functional integrity in the neural circuitry for behavioral regulation in children with FASD.

  4. Wetting layers effect on InAs/GaAs quantum dots

    Energy Technology Data Exchange (ETDEWEB)

    Sun Chao [State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, P.O. Box 49(BUPT), Xitucheng Road No. 10, Beijing 100876 (China); Lu Pengfei, E-mail: photon.bupt@gmail.com [State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, P.O. Box 49(BUPT), Xitucheng Road No. 10, Beijing 100876 (China); Yu Zhongyuan; Cao Huawei; Zhang Lidong [State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, P.O. Box 49(BUPT), Xitucheng Road No. 10, Beijing 100876 (China)

    2012-11-15

    FEM combining with the K{center_dot}P theory is adopted to systematically investigate the effect of wetting layers on the strain-stress profiles and electronic structures of self-organized InAs quantum dot. Four different kinds of quantum dots are introduced at the same height and aspect ratio. We found that 0.5 nm wetting layer is an appropriate thickness for InAs/GaAs quantum dots. Strain shift down about 3%{approx}4.5% for the cases with WL (0.5 nm) and without WL in four shapes of quantum dots. For band edge energy, wetting layers expand the potential energy gap width. When WL thickness is more than 0.8 nm, the band edge energy profiles cannot vary regularly. The electron energy is affected while for heavy hole this impact on the energy is limited. Wetting layers for the influence of the electronic structure is obviously than the heavy hole. Consequently, the electron probability density function spread from buffer to wetting layer while the center of hole's function moves from QDs internal to wetting layer when introduce WLs. When WLs thickness is larger than 0.8 nm, the electronic structures of quantum dots have changed obviously. This will affect the instrument's performance which relies on the quantum dots' optical properties.

  5. Study on radon and thoron progeny levels in Gudalore in South India

    International Nuclear Information System (INIS)

    Selvasekarapandian, S.; Sivakumar, R.; Mugunthamanikandan, N.; Meenakshisundaram, V.; Santhanam, R.

    2000-01-01

    One of the important route of radiation exposure to man is through inhalation of air containing radioisotopes. A major contribution to inhalation dose comes from radon, thoron and its progenies. The indoor radon and thoron progeny levels are determined by two count method. In this method the radon and thoron progenies are collected on a glass fiber filter paper using volume air sampler (Staplex) and counted for alpha activity in ZnS (Ag) alpha counting system. It is observed that thoron working level is higher than the radon working level in all houses except few houses with stone walls and mosaic floor. Behavior of indoor radon and thoron working levels for different seasons at different houses are determined and discussed in detail. Radon and thoron working levels are measured high in winter, autumn, and low in summer and rainy seasons. Among all seasons highest value is measured in winter and low in summer and rainy seasons. Radon progeny working level varies from 1.659 to 6.675 mWL, whereas thoron progeny working level varies from 1.670 to 12.671 mWL. The geometric mean values of radon and thoron progeny concentration in the present study are 2.836 and 4.133 mWL. The high thoron progeny level observed in this is attributed to the high thorium content observed in soils of this area. (author)

  6. A randomized trial comparing live and telemedicine deliveries of an imagery-based behavioral intervention for breast cancer survivors: reducing symptoms and barriers to care.

    Science.gov (United States)

    Freeman, Lyn W; White, Rebecca; Ratcliff, Chelsea G; Sutton, Sue; Stewart, Mary; Palmer, J Lynn; Link, Judith; Cohen, Lorenzo

    2015-08-01

    This multi-site randomized trial evaluates the quality of life (QOL) benefits of an imagery-based group intervention titled 'Envision the Rhythms of Life'(ERL). Breast cancer survivors >6 weeks post-treatment were randomized to attend five weekly 4-h group sessions at a community center with therapist present (live delivery (LD), n = 48), therapist streamed via telemedicine (telemedicine delivery (TD), n = 23), or to a waitlist control (WL) group (n = 47). Weekly individual phone calls to encourage at-home practice began at session one and continued until the 3-month follow-up. Seven self-report measures of QOL were examined at baseline, 1-month and 3-month post-treatments including health-related and breast cancer-specific QOL, fatigue, cognitive function, spirituality, distress, and sleep. The Bonferroni method was used to correct for multiple comparisons, and alpha was adjusted to 0.01. Linear multilevel modeling analyses revealed less fatigue, cognitive dysfunction, and sleep disturbance for LD and TD compared with WL across the follow-up (p's telemedicine delivered ERL intervention resulted in improvements in multiple QOL domains for breast cancer survivors compared with WL. Further, there were no significant differences between LD and TD, suggesting telemedicine delivered ERL intervention may represent an effective and viable option for cancer survivors in remote areas. Copyright © 2014 John Wiley & Sons, Ltd.

  7. Superconductivity

    International Nuclear Information System (INIS)

    Taylor, A.W.B.; Noakes, G.R.

    1981-01-01

    This book is an elementray introduction into superconductivity. The topics are the superconducting state, the magnetic properties of superconductors, type I superconductors, type II superconductors and a chapter on the superconductivity theory. (WL)

  8. Bloch electrons in 2D periodic electric and magnetic fields; Bloch-Elektronen in 2D periodischen elektrischen und magnetischen Feldern

    Energy Technology Data Exchange (ETDEWEB)

    Naundorf, B.

    2001-06-01

    The following topics were dealt with: electrons in periodic potentials, Bloch states, Landau states, wave packets, Harper equation, uncoupled Landau band states, matrix elements and matrix equations, periodic electric and magnetic fields (WL)

  9. Inelastic scattering to collective states in double-magic nuclei

    International Nuclear Information System (INIS)

    Wambach, J.

    1979-06-01

    The paper discusses several aspects of inelastic scattering to collective states in the framework of the 'Shell Model RPA Approximation' with special emphasis on the analysis of giant resonance states. (orig./WL) [de

  10. Natural radioactivity content in soil and indoor air of Chellanam.

    Science.gov (United States)

    Mathew, S; Rajagopalan, M; Abraham, J P; Balakrishnan, D; Umadevi, A G

    2012-11-01

    Contribution of terrestrial radiation due to the presence of naturally occurring radionuclides in soil and air constitutes a significant component of the background radiation exposure to the population. The concentrations of natural radionuclides in the soil and indoor air of Chellanam were investigated with an aim of evaluating the environmental radioactivity level and radiation hazard to the population. Chellanam is in the suburbs of Cochin, with the Arabian Sea in the west and the Cochin backwaters in the east. Chellanam is situated at ∼25 km from the sites of these factories. The data obtained serve as a reference in documenting changes to the environmental radioactivity due to technical activities. Soil samples were collected from 30 locations of the study area. The activity concentrations of (232)Th, (238)U and (40)K in the samples were analysed using gamma spectrometry. The gamma dose rates were calculated using conversion factors recommended by UNSCEAR [United Nations Scientific Committee on the Effects of Atomic Radiation. Sources and effects of ionizing radiation. UNSCEAR (2000)]. The ambient radiation exposure rates measured in the area ranged from 74 to 195 nGy h(-1) with a mean value of 131 nGy h(-1). The significant radionuclides being (232)Th, (238)U and (40)K, their activities were used to arrive at the absorbed gamma dose rate with a mean value of 131 nGy h(-1) and the radium equivalent activity with a mean value of 162 Bq kg(-1). The radon progeny levels varied from 0.21 to 1.4 mWL with a mean value of 0.6 mWL. The thoron progeny varied from 0.34 to 2.9 mWL with a mean value of 0.85 mWL. The ratio between thoron and radon progenies varied from 1.4 to 2.3 with a mean of 1.6. The details of the study, analysis and results are discussed.

  11. Nitric oxide is involved in light-specific responses of tomato during germination under normal and osmotic stress conditions.

    Science.gov (United States)

    Piterková, Jana; Luhová, Lenka; Hofman, Jakub; Turecková, Veronika; Novák, Ondrej; Petrivalsky, Marek; Fellner, Martin

    2012-09-01

    Nitric oxide (NO) is involved in the signalling and regulation of plant growth and development and responses to biotic and abiotic stresses. The photoperiod-sensitive mutant 7B-1 in tomato (Solanum lycopersicum) showing abscisic acid (ABA) overproduction and blue light (BL)-specific tolerance to osmotic stress represents a valuable model to study the interaction between light, hormones and stress signalling. The role of NO as a regulator of seed germination and ABA-dependent responses to osmotic stress was explored in wild-type and 7B-1 tomato under white light (WL) and BL. Germination data were obtained from the incubation of seeds on germinating media of different composition. Histochemical analysis of NO production in germinating seeds was performed by fluorescence microscopy using a cell-permeable NO probe, and endogenous ABA was analysed by mass spectrometry. The NO donor S-nitrosoglutathione stimulated seed germination, whereas the NO scavenger 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (PTIO) had an inhibitory effect. Under WL in both genotypes, PTIO strongly suppressed germination stimulated by fluridone, an ABA inhibitor. The stimulatory effect of the NO donor was also observed under osmotic stress for 7B-1 seeds under WL and BL. Seed germination inhibited by osmotic stress was restored by fluridone under WL, but less so under BL, in both genotypes. This effect of fluridone was further modulated by the NO donor and NO scavenger, but only to a minor extent. Fluorescence microscopy using the cell-permeable NO probe DAF-FM DA (4-amino-5-methylamino-2',7'-difluorofluorescein diacetate) revealed a higher level of NO in stressed 7B-1 compared with wild-type seeds. As well as defective BL signalling, the differential NO-dependent responses of the 7B-1 mutant are probably associated with its high endogenous ABA concentration and related impact on hormonal cross-talk in germinating seeds. These data confirm that light-controlled seed germination and

  12. Comparison of eye movement desensitization and reprocessing therapy, cognitive behavioral writing therapy, and wait-list in pediatric posttraumatic stress disorder following single-incident trauma: a multicenter randomized clinical trial.

    Science.gov (United States)

    de Roos, Carlijn; van der Oord, Saskia; Zijlstra, Bonne; Lucassen, Sacha; Perrin, Sean; Emmelkamp, Paul; de Jongh, Ad

    2017-11-01

    Practice guidelines for childhood posttraumatic stress disorder (PTSD) recommend trauma-focused psychotherapies, mainly cognitive behavioral therapy (CBT). Eye movement desensitization and reprocessing (EMDR) therapy is a brief trauma-focused, evidence-based treatment for PTSD in adults, but with few well-designed trials involving children and adolescents. We conducted a single-blind, randomized trial with three arms (n = 103): EMDR (n = 43), Cognitive Behavior Writing Therapy (CBWT; n = 42), and wait-list (WL; n = 18). WL participants were randomly reallocated to CBWT or EMDR after 6 weeks; follow-ups were conducted at 3 and 12 months posttreatment. Participants were treatment-seeking youth (aged 8-18 years) with a DSM-IV diagnosis of PTSD (or subthreshold PTSD) tied to a single trauma, who received up to six sessions of EMDR or CBWT lasting maximally 45 min each. Both treatments were well-tolerated and relative to WL yielded large, intent-to-treat effect sizes for the primary outcomes at posttreatment: PTSD symptoms (EMDR: d = 1.27; CBWT: d = 1.24). At posttreatment 92.5% of EMDR, and 90.2% of CBWT no longer met the diagnostic criteria for PTSD. All gains were maintained at follow-up. Compared to WL, small to large (range d = 0.39-1.03) intent-to-treat effect sizes were obtained at posttreatment for negative trauma-related appraisals, anxiety, depression, and behavior problems with these gains being maintained at follow-up. Gains were attained with significantly less therapist contact time for EMDR than CBWT (mean = 4.1 sessions/140 min vs. 5.4 sessions/227 min). EMDR and CBWT are brief, trauma-focused treatments that yielded equally large remission rates for PTSD and reductions in the severity of PTSD and comorbid difficulties in children and adolescents seeking treatment for PTSD tied to a single event. Further trials of both treatments with PTSD tied to multiple traumas are warranted. © 2017 Association for Child and Adolescent Mental

  13. Soil Respiration under Different Land Uses in Eastern China

    Science.gov (United States)

    Fan, Li-Chao; Yang, Ming-Zhen; Han, Wen-Yan

    2015-01-01

    Land-use change has a crucial influence on soil respiration, which further affects soil nutrient availability and carbon stock. We monitored soil respiration rates under different land-use types (tea gardens with three production levels, adjacent woodland, and a vegetable field) in Eastern China at weekly intervals over a year using the dynamic closed chamber method. The relationship between soil respiration and environmental factors was also evaluated. The soil respiration rate exhibited a remarkable single peak that was highest in July/August and lowest in January. The annual cumulative respiration flux increased by 25.6% and 20.9% in the tea garden with high production (HP) and the vegetable field (VF), respectively, relative to woodland (WL). However, no significant differences were observed between tea gardens with medium production (MP), low production (LP), WL, and VF. Soil respiration rates were significantly and positively correlated with organic carbon, total nitrogen, and available phosphorous content. Each site displayed a significant exponential relationship between soil respiration and soil temperature measured at 5 cm depth, which explained 84–98% of the variation in soil respiration. The model with a combination of soil temperature and moisture was better at predicting the temporal variation of soil respiration rate than the single temperature model for all sites. Q10 was 2.40, 2.00, and 1.86–1.98 for VF, WL, and tea gardens, respectively, indicating that converting WL to VF increased and converting to tea gardens decreased the sensitivity of soil respiration to temperature. The equation of the multiple linear regression showed that identical factors, including soil organic carbon (SOC), soil water content (SWC), pH, and water soluble aluminum (WSAl), drove the changes in soil respiration and Q10 after conversion of land use. Temporal variations of soil respiration were mainly controlled by soil temperature, whereas spatial variations were

  14. Effect of vacuum impregnation temperature on the mechanical properties and osmotic dehydration parameters of apples

    Directory of Open Access Journals (Sweden)

    Sabrina Silva Paes

    2008-08-01

    Full Text Available The effect of sucrose solution temperature on the mechanical properties, water loss (WL, solids gain (SG and weight reduction (WR of apples (Fuji var. treated by vacuum impregnation was studied. Temperatures were varied from 10 to 50 ºC, using a sucrose solution of 50 ºBrix. The mechanical properties were studied throughout a stress relaxation test. The results showed that the SG varied between 10.57 and 14.29 % and the WL varied between 10.55 and 14.48 %. The treated fruit soluble solids increased with the temperature probably due to the lower viscosity of the solution. The maximum stress was highest at 10 ºC, decreasing at higher temperatures, probably due the softening of the structure.A impregnação a vácuo (VI de alimentos é realizada pela aplicação de vácuo em um tanque contendo o produto imerso em uma solução, seguida da recuperação da pressão atmosférica. Neste trabalho, estudou-se o efeito da temperatura da solução de sacarose nas propriedades mecânicas das amostras e na perda de água (WL, ganho de sólidos (SG e redução de peso (WR. A faixa de temperaturas estudada foi de 10 a 50 ºC, usando uma solução de sacarose com 50 ºBrix. As propriedades mecânicas das amostras foram estudadas através de ensaios mecânicos de deformação-relaxação. O SG variou entre 10.57 e 14.29 %, enquanto WL variou entre 10.55 e 14.48 %. O teor de sólidos das frutas tratadas aumentou com a temperatura, provavelmente devido à diminuição da viscosidade da solução. A tensão máxima foi maior a 10 ºC, diminuindo com a temperatura, devido ao amolecimento da estrutura.

  15. Three-year follow-up comparing metabolic surgery versus medical weight management in patients with type 2 diabetes and BMI 30-35. The role of sRAGE biomarker as predictor of satisfactory outcomes.

    Science.gov (United States)

    Horwitz, Daniel; Saunders, John K; Ude-Welcome, Aku; Marie Schmidt, Ann; Dunn, Van; Leon Pachter, H; Parikh, Manish

    2016-08-01

    Patients with type 2 diabetes (T2D) and body mass index (BMI)<35 may benefit from metabolic surgery. The soluble form of the receptor for advanced glycation end products (sRAGE) may identify patients at greater chance for T2D remission. To study long-term outcomes of patients with T2D and BMI 30-35 treated with metabolic surgery or medical weight management (MWM) and search for predictors of T2D remission. University METHODS: Retrospective review of the original cohort, including patients who crossed over from MWM to surgery. Repeated-measures linear models were used to model weight loss (%WL), change in glycated hemoglobin (HbA1C) and association with baseline sRAGE. Fifty-seven patients with T2D and BMI 30-35 were originally randomly assigned to metabolic surgery versus MWM. Mean BMI and HbA1C was 32.6% and 7.8%, respectively. A total of 30 patients underwent surgery (19 sleeves, 8 bypasses, 3 bands). Three-year follow-up in the surgery group and MWM group was 75% and 86%, respectively. Surgery resulted in higher T2D remission (63% versus 0%; P<.001) and lower HbA1C (6.9% versus 8.4%; P<.001) for up to 3 years. There was no difference in %WL in those with versus those without T2D remission (21.7% versus 20.6%, P = .771), suggesting that additional mechanisms other than %WL play an important role for the studied outcome. Higher baseline sRAGE was associated with greater change in HbA1C and greater %WL after surgery (P< .001). Metabolic surgery was effective in promoting remission of T2D in 63% of patients with BMI 30-35; higher baseline sRAGE predicted T2D remission with surgery. Larger-scale randomly assigned trials are needed in this patient population. Copyright © 2016 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

  16. Formerly utilized MED/AEC sites remedial action program: radiological survey of the Building Site 421, United States, Watertown Arsenel, Watertown, MA. Final report

    International Nuclear Information System (INIS)

    1980-02-01

    This report contains the results of surveys of the current radiological condition of the Building Site 421, United States Arsenal Watertown, Watertown, Massachusetts. Findings of this survey indicate there are four spots involving an area of less than 6000 cm 2 of identifiable low-level residual radioactivity on the concrete pad which is all that remains of Building Site 421. The largest spot is approximately 5000 cm 2 . The other three spots are 100 cm 2 or less. The beta-gamma readings at these spots are 8.4 x 10 2 dis/min-100 cm 2 , 2.2 x 10 5 dis/min-100 cm 2 , 2.2 x 10 5 dis/min-100 cm 2 and 8.5 x 10 4 dis/min-100 cm 2 . No alpha contamination was found at these locations. Gamma spectral analysis of a chip of contaminated concrete from one of the spots indicates that the contaminant is natural uranium. This contamination is fixed in the concrete and does not present an internal or external exposure hazard under present conditions. A hypothetical hazard analysis under a conservative set of assumed conditions indicates minimal internal hazard. The highest End Window contact reading was 0.09 mR/h. None of the other three spots indicated an elevated direct reading with the End Window Detector. Radon daughter concentrations were determined at three locations on the Building 421 pad. These were 0.00013 WL, 0.00011 WL and 0.00009 WL. According to the Surgeon General's Guidelines found in 10 CFR 712, radon daughter concentrations below 0.03 WL do not require remedial action in structures other than private dwellings and schools. Soil samples taken about the site indicate no elevated levels above the natural background levels in the soil. A gamma spectral analysis of a water sample obtained from the storm sewer line near the Building 421 pad indicates no elevated radioactivity in the sample. It was therefore felt that no contamination is present in this sewer

  17. Serum Polychlorinated Biphenyls Increase and Oxidative Stress Decreases with a Protein-Pacing Caloric Restriction Diet in Obese Men and Women

    Directory of Open Access Journals (Sweden)

    Feng He

    2017-01-01

    Full Text Available The purposes were to compare the effects of a: (1 12-week P-CR weight loss (WL diet (Phase 1 between obese men and women and; (2 52-week modified P-CR (mP-CR vs. heart healthy (HH weight maintenance (WM diet (Phase 2 on serum PCBs and oxidative stress biomarkers (thiobarbituric acid reactive substances, TBARS; total antioxidant capacity, TAC in 40 obese participants (men, n = 21; women, n = 19. Participants received dietary counseling and monitoring of compliance. PCBs, TBARS, and TAC were assessed at weeks −1 (CON, 12 (WL, and 64 (WM. Following WL (Week 12, concomitant with reductions in TBARS (0.24 ± 0.15 vs. 0.18 ± 0.11 µM; p < 0.01, PCB serum concentrations (86.7 ± 45.6 vs. 115.6 ± 65.9 ng/g lipid; p < 0.01 and TAC (18.9 ± 2.6 vs. 19.9 ± 2.3 nmol/mL; p < 0.02 were increased similarly in men and women. At the end of WM (Week 64, a significant effect of time × group interaction was observed for % change in PCB 170 and 187; whereby mP-CR values were higher compared to HH (PCB170: 19.31% ± 26.48% vs. −6.61% ± 28.88%, p = 0.02; PCB187: −3.04% ± 17.78% vs. −21.4% ± 27.31%, p = 0.04. PCB changes were positively correlated with TBARS levels (r > 0.42, p < 0.05 and negatively correlated with body weight, fat mass, and abdominal fat (r < −0.46, p < 0.02. Our results support mobilization of stored PCBs as well as enhanced redox status following a 12-week P-CR WL diet. Additionally, a 52-week mP-CR WM diet demonstrated an advantage in preventing weight gain relapse accompanied by an increase in circulating PCBs compared to a traditional HH diet.

  18. Turundus peab tantsima tarbija tujude järgi / Anne Tuurand

    Index Scriptorium Estoniae

    Tuurand, Anne

    2000-01-01

    Kuidas mõjutavad ühiskonnas toimuvad muutused tarbimist ja turundust. Uudistoodete omaksvõtt ja omaksvõtjate erinevused. Turundusstrateegia sõltuvus tarbijakäitumist kujundavatest teguritest. Artikli kirjutamise alus: W.L. Wilkie "Consumer Behavior", 1990

  19. Decommissioning of Active Ventilation Systems in a Nuclear R and D Facility to Prepare for Building Demolition (Whiteshell Laboratories Decommissioning Project, Canada) - 13073

    International Nuclear Information System (INIS)

    Wilcox, Brian; May, Doug; Howlett, Don; Bilinsky, Dennis

    2013-01-01

    Whiteshell Laboratories (WL) is a nuclear research establishment owned by the Canadian government and operated by Atomic Energy of Canada Limited (AECL) since the early 1960's. WL is currently under a decommissioning license and the mandate is to remediate the nuclear legacy liabilities in a safe and cost effective manner. The WL Project is the first major nuclear decommissioning project in Canada. A major initiative underway is to decommission and demolish the main R and D Laboratory complex. The Building 300 R and D complex was constructed to accommodate laboratories and offices which were mainly used for research and development associated with organic-cooled reactors, nuclear fuel waste management, reactor safety, advanced fuel cycles and other applications of nuclear energy. Building 300 is a three storey structure of approximately 16,000 m 2 . In order to proceed with building demolition, the contaminated systems inside the building have to be characterized, removed, and the waste managed. There is a significant focus on volume reduction of radioactive waste for the WL project. The active ventilation system is one of the significant contaminated systems in Building 300 that requires decommissioning and removal. The active ventilation system was designed to manage hazardous fumes and radioactivity from ventilation devices (e.g., fume hoods, snorkels and glove boxes) and to prevent the escape of airborne hazardous material outside of the laboratory boundary in the event of an upset condition. The system includes over 200 ventilation devices and 32 active exhaust fan units and high efficiency particulate air (HEPA) filters. The strategy to remove the ventilation system was to work from the laboratory end back to the fan/filter system. Each ventilation duct was radiologically characterized. Fogging was used to minimize loose contamination. Sections of the duct were removed by various cutting methods and bagged for temporary storage prior to disposition

  20. Similar and Contrasting Response of Rifting and Transtension in the Gulf of California and Walker Lane to Preceding Arc Magmatism

    Science.gov (United States)

    Henry, C. D.; Faulds, J. E.

    2006-12-01

    The Gulf of California (GC) and Walker Lane (WL) have undergone strikingly similar development with strike- slip faulting following initial extension. They differ significantly in the amount of Pacific-North American plate motion taken up by each: essentially all relative motion in the GC and ~25% in the WL. In both areas, ancestral arc magmatism preceded and probably focused deformation, perhaps because heating and/or hydration weakened the lithosphere. However, differences in migration of the Rivera (RTJ) and Mendocino triple junctions (MTJ) related to differences in the orientation of plate boundaries determined how strike-slip faulting developed. Abrupt southward jumps in the RTJ led to abrupt cessation of magmatism over arc lengths of as much as 1000 km and initiation of east-northeast extension within the future GC. The best known jump was at ~13 Ma, but an earlier jump occurred at ~18 Ma. Arc magmatism has been best documented in Baja California, Sonora, and Nayarit, although Baja constituted the most-trenchward fringe of the ancestral arc. New and published data indicate that Sinaloa underwent a similar history of arc magmatism. The greatest volume of the arc immediately preceding RTJ jumps was probably in mainland Mexico. Arc magmatism shut off following these jumps, extension began in the future GC, and strike-slip faulting either followed or accompanied extension in the GC. In contrast, the MTJ migrated progressively northward. New and published data indicate magmatism generally shut off coincident with this retreat, but distinct nodes or zones of magmatism, presumably unrelated to subduction, persisted or initiated after arc activity ceased. We have suggested that the WL has grown progressively northward, following the retreating arc, and that the northern WL is its youngest part. However, the timing of initiation of strike-slip faulting in most of the WL is poorly known and controversial. Testing our hypothesis requires determining initiation and

  1. Antenna analysis using neural networks

    Science.gov (United States)

    Smith, William T.

    1992-01-01

    Conventional computing schemes have long been used to analyze problems in electromagnetics (EM). The vast majority of EM applications require computationally intensive algorithms involving numerical integration and solutions to large systems of equations. The feasibility of using neural network computing algorithms for antenna analysis is investigated. The ultimate goal is to use a trained neural network algorithm to reduce the computational demands of existing reflector surface error compensation techniques. Neural networks are computational algorithms based on neurobiological systems. Neural nets consist of massively parallel interconnected nonlinear computational elements. They are often employed in pattern recognition and image processing problems. Recently, neural network analysis has been applied in the electromagnetics area for the design of frequency selective surfaces and beam forming networks. The backpropagation training algorithm was employed to simulate classical antenna array synthesis techniques. The Woodward-Lawson (W-L) and Dolph-Chebyshev (D-C) array pattern synthesis techniques were used to train the neural network. The inputs to the network were samples of the desired synthesis pattern. The outputs are the array element excitations required to synthesize the desired pattern. Once trained, the network is used to simulate the W-L or D-C techniques. Various sector patterns and cosecant-type patterns (27 total) generated using W-L synthesis were used to train the network. Desired pattern samples were then fed to the neural network. The outputs of the network were the simulated W-L excitations. A 20 element linear array was used. There were 41 input pattern samples with 40 output excitations (20 real parts, 20 imaginary). A comparison between the simulated and actual W-L techniques is shown for a triangular-shaped pattern. Dolph-Chebyshev is a different class of synthesis technique in that D-C is used for side lobe control as opposed to pattern

  2. Use of anthocyanin extracted from natural plant materials to develop ...

    African Journals Online (AJOL)

    ajl yemi

    2011-12-19

    Dec 19, 2011 ... 3Faculty of Industrial Education, King Mongkut's Institute of Technology Ladkrabang, Ladkrabang, Bangkok ..... (Figure 3d) and BPF+WL extract (Figure 3e) were tested ..... Tippanate Printing Press, Bangkok, Thailand. p. 818.

  3. Ultraviolet study of V1341 CYG = CYG X-2

    International Nuclear Information System (INIS)

    Chiappetti, L.; Treves, A.; Maraschi, L.; Consiglio Nazionale delle Ricerche, Milan; Tanzi, E.G.

    1981-01-01

    In this paper we discuss observations with I.U.E. in the range 1200-3000 A, with particular reference to the continuum. Some spectra have been already presented elsewhere (Maraschi et al, 1980). (orig./WL)

  4. Cytomegalovirus (CMV) infection

    Science.gov (United States)

    ... If your immune system becomes weakened in the future, this virus may have the chance to reactivate, ... 140. Drew WL. Cytomegalovirus. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  5. Genetics Home Reference: carnitine palmitoyltransferase II deficiency

    Science.gov (United States)

    ... PubMed Isackson PJ, Bennett MJ, Lichter-Konecki U, Willis M, Nyhan WL, Sutton VR, Tein I, Vladutiu ... 27 [updated 2017 Mar 16]. In: Pagon RA, Adam MP, Ardinger HH, Wallace SE, Amemiya A, Bean ...

  6. Influence of borehole-eccentred tools on wireline and logging-while-drilling sonic logging measurements

    KAUST Repository

    Pardo, David; Matuszyk, Paweł Jerzy; Torres-Verdí n, Carlos; Mora Cordova, Angel; Muga, Ignacio; Calo, Victor M.

    2013-01-01

    We describe a numerical study to quantify the influence of tool-eccentricity on wireline (WL) and logging-while-drilling (LWD) sonic logging measurements. Simulations are performed with a height-polynomial-adaptive (hp) Fourier finite-element method

  7. Reduced thermal quenching in indium-rich self-organized InGaN/GaN quantum dots

    KAUST Repository

    Elafandy, Rami T.; Bhattacharya, Pallab K.; Cha, Dong Kyu; Ng, Tien Khee; Ooi, Boon S.; Zhang, Meng

    2012-01-01

    Differences in optical and structural properties of indium rich (27), indium gallium nitride (InGaN) self-organized quantum dots (QDs), with red wavelength emission, and the two dimensional underlying wetting layer (WL) are investigated. Temperature

  8. What do we learn on the dynamics of fission from α-accompanied fission data

    International Nuclear Information System (INIS)

    Guet, C.; Asghar, M.; Nifenecker, H.; Perrin, P.

    1978-01-01

    Measurements of the angular distribution of α-particles emitted by thermal fission of 236 U are presented. Also the dependence of the angular distribution on the kinetic energy of the fission products is studied. (WL) [de

  9. Is PKS 2155 an extragalactic source

    International Nuclear Information System (INIS)

    Maraschi, L.; Treves, A.

    1981-01-01

    We present here observations in the far ultraviolet (1200-3000 Angstroem) obtained with I.U.E. The presence of weak variable emission features is discussed and the extragalactic nature of the object is questioned. (orig./WL)

  10. The Ceremonial Side of Training--Of What Value to First-Line Supervisors?

    Science.gov (United States)

    Adams, Fred P.

    1976-01-01

    A case study to determine whether the recognition of being selected for a training program and the satisfactory completion of it result in increased job satisfaction using 56 first-line supervisors from a textile company. (WL)

  11. Comparison of various current electronic apex locators to determine ...

    African Journals Online (AJOL)

    2014-10-16

    Oct 16, 2014 ... measurements of the WL, especially in cases of infected necrotic pulps and chronic apical periodontitis, led to significantly lower ..... root canal length: A preliminary report using the Tri Auto ZX apex‑locating handpiece.

  12. 75 FR 4443 - Petition for Declaratory Order by Fullington Trailways, LLC

    Science.gov (United States)

    2010-01-27

    ... Brown's Crew Car of Wyo. LLC v. Nevada Transp. Auth., 2009 WL 1240458, at 12 (D. Nev. May 1, 2009... such as door-to-door service, day trips to race tracks, casinos, sporting events, or other excursions...

  13. Collective description of magnetic properties of even-even nuclei

    International Nuclear Information System (INIS)

    Maruhn, V.

    1975-01-01

    The generalized collective model is modified by introducing a number of quadrupole deformations for protons and neutrons. The coupling potential is described by physical approaches, and the overall model is applied to even-even nuclei. (WL) [de

  14. Investigations on the growth of a-oriented layers of high temperature superconductors

    International Nuclear Information System (INIS)

    Sodtke, E.

    1992-10-01

    The properties of a-oriented YBaCuO and PrBaCuO layers were investigated. The layers are grown in a modified template method and analyzed by X-ray diffraction, Raman spectroscopy and Hall measurements. (WL)

  15. Cross section determination for the higher ionization of rare gas ions by electron collisions

    International Nuclear Information System (INIS)

    Becker, R.; Frodl, R.; Klein, H.; Schmidt, W.; Clausnitzer, G.; Klinger, H.; Mueller, A.; Salzborn, E.; Fuchs, G.; Viehboeck, F.

    1975-01-01

    The higher ionization of rare gas ions is reported on, which were excited by an electron beam using a crossed-beam technique. A detector for the identification of metastable excited rare gas ions was developed. (WL) [de

  16. Comparative study of 6 rotary nickel-titanium systems and hand instrumentation for root canal preparation in severely curved root canals of extracted teeth.

    Science.gov (United States)

    Celik, Davut; Taşdemir, Tamer; Er, Kürşat

    2013-02-01

    Some improvements have been developed with new generations of nickel-titanium (NiTi) rotary instruments that led to their successful and extensive application in clinical practice. The purpose of this in vitro study was to compare the root canal preparations performed by using GT Series X and Twisted File systems produced by innovative manufacturing process with Revo-S, RaCe, Mtwo, and ProTaper Universal systems manufactured directly from conventional nitinol and with stainless steel K-Flexofile instruments. The mesiobuccal root canals of 140 maxillary first permanent molars that had between 30°-40° curvature angle and 4- to 9-mm curvature radius of the root canal were used. After root canal preparations made by using GT Series X, Twisted File, Revo-S, RaCe, Mtwo, and ProTaper Universal NiTi rotary systems and stainless steel K-Flexofile instruments, transportation occurred in the root canal, and alteration of working length (WL) was assessed by using a modified double-digital radiographic technique. The data were compared by the post hoc Tukey honestly significant difference test. NiTi rotary systems caused less canal transportation and alteration of WL than K-Flexofile instruments (P .05) except 2.5 mm from the WL. At this level ProTaper Universal system caused significant canal transportation (P ProTaper Universal rotary systems manufactured by traditional methods. Copyright © 2013 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  17. Internet-based treatment for panic disorder: A three-arm randomized controlled trial comparing guided (via real-time video sessions) with unguided self-help treatment and a waitlist control. PAXPD study results.

    Science.gov (United States)

    Ciuca, Amalia M; Berger, Thomas; Crişan, Liviu G; Miclea, Mircea

    2018-05-01

    A growing body of evidence suggests that Internet-based cognitive behavioral treatments (ICBT) are effective to treat anxiety disorders. However, the effect of therapist guidance in ICBT is still under debate and guided ICBT offered in a real-time audio-video communication format has not yet been systematically investigated. This three-arm RCT compared the efficacy of guided with unguided ICBT (12 weeks intervention) and a waitlist (WL). A total of 111 individuals meeting the diagnostic criteria for panic disorder (PD) were randomly assigned to one of three conditions. Primary outcomes were the severity of self-report panic symptoms and diagnostic status. Secondary outcomes were symptoms of depression, functional impairment, catastrophic cognitions, fear of sensations and body vigilance. At post-treatment, both active conditions showed superior outcomes regarding PD and associated symptoms (guided ICBT vs. WL: d = 1.04-1.36; unguided ICBT vs. WL: d = 0.70-1.06). At post-treatment, the two active conditions did not differ significantly in self-reported symptom reduction (d = 0.21-0.54, all ps > 0.05), but the guided treatment was superior to the unguided treatment in terms of diagnostic status (χ 2 (1) = 13.15, p < 0.01). Treatment gains were maintained at successive follow-ups and the guided treatment became superior to the unguided treatment at 6 months follow-up (d = 0.72-1.05, all ps < 0.05). Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. Effects of mindfulness-based stress reduction on depression, anxiety, stress and mindfulness in Korean nursing students.

    Science.gov (United States)

    Song, Yeoungsuk; Lindquist, Ruth

    2015-01-01

    Nursing students often experience depression, anxiety, stress and decreased mindfulness which may decrease their patient care effectiveness. Mindfulness-based stress reduction (MBSR) effectively reduced depression, anxiety and stress, and increased mindfulness in previous research with other populations, but there is sparse evidence regarding its effectiveness for nursing students in Korea. To examine the effects of MBSR on depression, anxiety, stress and mindfulness in Korean nursing students. A randomized controlled trial. Fifty (50) nursing students at KN University College of Nursing in South Korea were randomly assigned to two groups. Data from 44 students, MBSR (n=21) and a wait list (WL) control (n=23) were analyzed. The MBSR group practiced mindfulness meditation for 2 h every week for 8 weeks. The WL group did not receive MBSR intervention. Standardized self-administered questionnaires of depression, anxiety, stress and mindfulness were administered at the baseline prior to the MBSR program and at completion (at 8 weeks). Compared with WL participants, MBSR participants reported significantly greater decreases in depression, anxiety and stress, and greater increase in mindfulness. A program of MBSR was effective when it was used with nursing students in reducing measures of depression, anxiety and stress, and increasing their mindful awareness. MBSR shows promise for use with nursing students to address their experience of mild depression, anxiety and stress, and to increase mindfulness in academic and clinical work, warranting further study. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Protein-Pacing Caloric-Restriction Enhances Body Composition Similarly in Obese Men and Women during Weight Loss and Sustains Efficacy during Long-Term Weight Maintenance.

    Science.gov (United States)

    Arciero, Paul J; Edmonds, Rohan; He, Feng; Ward, Emery; Gumpricht, Eric; Mohr, Alex; Ormsbee, Michael J; Astrup, Arne

    2016-07-30

    Short-Term protein-pacing (P; ~6 meals/day, >30% protein/day) and caloric restriction (CR, ~25% energy deficit) improves total (TBF), abdominal (ABF) and visceral (VAT) fat loss, energy expenditure, and biomarkers compared to heart healthy (HH) recommendations (3 meals/day, 15% protein/day) in obese adults. Less is known whether obese men and women respond similarly to P-CR during weight loss (WL) and whether a modified P-CR (mP-CR) is more efficacious than a HH diet during long-term (52 week) weight maintenance (WM). The purposes of this study were to evaluate the efficacy of: (1) P-CR on TBF, ABF, resting metabolic rate (RMR), and biomarkers between obese men and women during WL (weeks 0-12); and (2) mP-CR compared to a HH diet during WM (weeks 13-64). During WL, men (n = 21) and women (n = 19) were assessed for TBF, ABF, VAT, RMR, and biomarkers at weeks 0 (pre) and 12 (post). Men and women had similar reductions (p 50%) and increase in % lean body mass (9%). RMR (kcals/kg bodyweight) was unchanged and respiratory quotient decreased 9%. Twenty-four subjects (mP-CR, n = 10; HH, n = 14) completed WM. mP-CR regained significantly less body weight (6%), TBF (12%), and ABF (17%) compared to HH (p < 0.05). Our results demonstrate P-CR enhances weight loss, body composition and biomarkers, and maintains these changes for 52-weeks compared to a traditional HH diet.

  20. A new computed tomography method to identify meningitis-related cochlear ossification and fibrosis before cochlear implantation.

    Science.gov (United States)

    Ichikawa, Kazunori; Kashio, Akinori; Mori, Harushi; Ochi, Atushi; Karino, Shotaro; Sakamoto, Takashi; Kakigi, Akinobu; Yamasoba, Tatsuya

    2014-04-01

    To develop a new method to determine the presence of intracochlear ossification and/or fibrosis in cochlear implantation candidates with bilateral profound deafness following meningitis. Diagnostic test assessment. A university hospital. This study involved 15 ears from 13 patients with profound deafness following meningitis who underwent cochlear implantation. These ears showed normal structures, soft tissue, partial bony occlusion, and complete bony occlusion in 4, 3, 2, and 6 ears, respectively. We measured radiodensity in Hounsfield units (HU) using 0.5-mm-thick axial high-resolution computed tomography image slices at 3 different levels in the basal turn, the fenestration, and inferior and ascending segment sites, located along the electrode-insertion path. Pixel-level analysis on the DICOM viewer yielded actual computed tomography values of intracochlear soft tissues by eliminating the partial volume effect. The values were compared with the intraoperative findings. Values for ossification (n = 12) ranged from +547 HU to +1137 HU; for fibrosis (n = 11), from +154 HU to +574 HU; and for fluid (n = 22), from -49 HU to +255 HU. From these values, we developed 2 presets of window width (WW) and window level (WL): (1) WW: 1800, WL: 1100 (200 HU to 2000 HU) and (2) WW: 1500, WL: 1250 (500 HU to 2000 HU). The results using these 2 presets corresponded well to the intraoperative findings. Our new method is easy and feasible for preoperative determination of the presence of cochlear ossification and/or fibrosis that develops following meningitis.

  1. Uranium Mill Tailings Remedial Action Program. Partial radiological survey of Shiprock vicinity property SH13 Shiprock, New Mexico, November 1982

    International Nuclear Information System (INIS)

    Flynn, K.F.; Justus, A.L.; Sholeen, C.M.; Smith, W.H.; Wynveen, R.A.

    1984-05-01

    As part of a detailed radiological assessment of the vicinity properties at Shiprock, a comprehensive survey of the vicinity property designated as SH13 was initiated on November 19, 1982. At that time, a single residential structure existed in the northwest corner of the property. The lands surrounding the structure were extensively cluttered with junk. The initial assessment activities were limited to measurements within the residential structure of the ambient external penetrating radiation level at a 1-meter height and analyses of indoor air samples for airborne radioactivity. The external penetrating radiation exposure rate (12.3 μR/h) was less than the 20 μR/h above background limit specified in the EPA Standard (40 CFR 192.12[b][2]). As determined by the air samples, the short-term radon daughter concentration within the structure (0.36 mWL) did not exceed the 0.02 WL (or 20 mWL) limit for average annual concentration including background as specified in the EPA Standard. Further measurements required to completely determine the radiological status of this vicinity property, such as measurements of surface radiation both indoors and outdoors and collection and analyses of soil samples, were planned for the final phase of this assessment. However, that phase of the program was terminated before these measurements were accomplished. Thus, the extent of outdoor radiological contamination is presently unknown, and the evaluation of indoor contamination (if any) is incomplete

  2. Optimisation of window settings for traditional and noise-optimised virtual monoenergetic imaging in dual-energy computed tomography pulmonary angiography

    International Nuclear Information System (INIS)

    D'Angelo, Tommaso; ''G. Martino'' University Hospital, Messina; Bucher, Andreas M.; Lenga, Lukas; Arendt, Christophe T.; Peterke, Julia L.; Martin, Simon S.; Leithner, Doris; Vogl, Thomas J.; Wichmann, Julian L.; Caruso, Damiano; University Hospital, Latina; Mazziotti, Silvio; Blandino, Alfredo; Ascenti, Giorgio; University Hospital, Messina; Othman, Ahmed E.

    2018-01-01

    To define optimal window settings for displaying virtual monoenergetic images (VMI) of dual-energy CT pulmonary angiography (DE-CTPA). Forty-five patients who underwent clinically-indicated third-generation dual-source DE-CTPA were retrospectively evaluated. Standard linearly-blended (M 0 .6), 70-keV traditional VMI (M70), and 40-keV noise-optimised VMI (M40+) reconstructions were analysed. For M70 and M40+ datasets, the subjectively best window setting (width and level, B-W/L) was independently determined by two observers and subsequently related with pulmonary artery attenuation to calculate separate optimised values (O-W/L) using linear regression. Subjective evaluation of image quality (IQ) between W/L settings were assessed by two additional readers. Repeated measures of variance were performed to compare W/L settings and IQ indices between M 0 .6, M70, and M40+. B-W/L and O-W/L for M70 were 460/140 and 450/140, and were 1100/380 and 1070/380 for M40+, respectively, differing from standard DE-CTPA W/L settings (450/100). Highest subjective scores were observed for M40+ regarding vascular contrast, embolism demarcation, and overall IQ (all p<0.001). Application of O-W/L settings is beneficial to optimise subjective IQ of VMI reconstructions of DE-CTPA. A width slightly less than two times the pulmonary trunk attenuation and a level approximately of overall pulmonary vessel attenuation are recommended. (orig.)

  3. Validity of the Born approximation for beyond Gaussian weak lensing observables

    Science.gov (United States)

    Petri, Andrea; Haiman, Zoltán; May, Morgan

    2017-06-01

    Accurate forward modeling of weak lensing (WL) observables from cosmological parameters is necessary for upcoming galaxy surveys. Because WL probes structures in the nonlinear regime, analytical forward modeling is very challenging, if not impossible. Numerical simulations of WL features rely on ray tracing through the outputs of N -body simulations, which requires knowledge of the gravitational potential and accurate solvers for light ray trajectories. A less accurate procedure, based on the Born approximation, only requires knowledge of the density field, and can be implemented more efficiently and at a lower computational cost. In this work, we use simulations to show that deviations of the Born-approximated convergence power spectrum, skewness and kurtosis from their fully ray-traced counterparts are consistent with the smallest nontrivial O (Φ3) post-Born corrections (so-called geodesic and lens-lens terms). Our results imply a cancellation among the larger O (Φ4) (and higher order) terms, consistent with previous analytic work. We also find that cosmological parameter bias induced by the Born-approximated power spectrum is negligible even for a LSST-like survey, once galaxy shape noise is considered. When considering higher order statistics such as the κ skewness and kurtosis, however, we find significant bias of up to 2.5 σ . Using the LensTools software suite, we show that the Born approximation saves a factor of 4 in computing time with respect to the full ray tracing in reconstructing the convergence.

  4. Measurement of potential alpha energy concentration in some schools in Shillong city

    International Nuclear Information System (INIS)

    Maibam, Deveshwori; Sharma, Yubaraj; Saxena, Atul; Walia, Devesh; Diengdoh, Evamary; Rapmai, Aibora K.

    2011-01-01

    Radon and its progeny account for more than 50% of total natural radiation exposure to humans and are considered to an important cause of lung cancer (UNSCEAR, 2008). Indoor radon levels are much higher than outdoor levels hence the importance of assessing radon levels in indoor environments, particularly schools which serve as a significant source of radon exposure both for children and the staffs. Children have smaller lung volumes and higher breathing rates therefore an augmented radon concentration results to a higher radiation dose in children. In our study, potential alpha energy concentration (PAEC) of 20 schools in Shillong region has been measured using the SSNTD method with LR-115 type 2 detectors. The detectors in bare mode were placed in class rooms at different floors of each school during winter and summer season. The detectors in bare mode were placed in class rooms at diff rent floors of each school during winter and summer season. The PAEC (mWL) at each of the selected schools are calculated and it ranges from 2.56 - 58.2 mWL (Arithmetic mean) and 2.34 - 58.18 mWL (Geometric mean). And the annual effective dose equivalent (AEDE) ranges from 0.74 - 17.85 mSv.y -1 . This preliminary study shows that the AEDE values of the schools under study are below the prescribed action limit by AERB i.e. 30 mSv.y -1 . (author)

  5. Three-dimensional nanostructures on Ge/Si(100) wetting layers: Hillocks and pre-quantum dots

    International Nuclear Information System (INIS)

    Ramalingam, Gopalakrishnan; Floro, Jerrold A.; Reinke, Petra

    2016-01-01

    The annealing of sub-critical Ge wetting layers (WL < 3.5 ML) initiates the formation of 3D nanostructures, whose shape and orientation is determined by the WL thickness and thus directly related to the strain energy. The emergence of these nanostructures, hillocks and pre-quantum dots, is studied by scanning tunneling microscopy. A wetting layer deposited at 350 °C is initially rough on the nanometer length-scale and undergoes a progressive transformation and smoothening during annealing at T < 460 °C when vacancy lines and the 2xn reconstruction are observed. The metastable Ge WL then collapses to form 3D nanostructures whose morphology is controlled by the WL thickness: first, the hillocks, with a wedding cake-type structure where the step edges run parallel to the 〈110〉 direction, are formed from thin wetting layers, while {105}-faceted structures, called pre-quantum dots (p-QDs), are formed from thicker layers. The wetting layer thickness and thus the misfit strain energy controls the type of structure. The crossover thickness between the hillock and p-QDs regime is between 1.6 and 2.1 ML. The hillocks have larger lateral dimensions and volumes than p-QDs, and the p-QDs are exceptionally small quantum dots with a lower limit of 10 nm in width. Our work opens a new pathway to the control of nanostructure morphology and size in the elastically strained Ge/Si system.

  6. Review of some experimental results on e-e+ annihilation

    International Nuclear Information System (INIS)

    Lohrmann, E.

    1977-01-01

    The headings of this review are: physics below 3 GeV cm energy, total cross sections and inclusive measurements above 3 GeV cm energy, charmonium, inclusive electron production, charmed particles and the heavy lepton tau. (WL) [de

  7. Ab initio Molecular Orbital Studies of the Vibrational Spectra of some ...

    African Journals Online (AJOL)

    NJD

    2004-06-15

    Jun 15, 2004 ... molecular complexes containing the family of Lewis acids carbon dioxide ..... cating a successively weaker interaction along the series. For. SO2. ..... Schleyer, H.F. Schaefer III, P.R. Scheiner, W.L. Jorgensen, W. Thiel and.

  8. Cassava (Manihot esculenta Crantz) is a widely grown root crop in ...

    African Journals Online (AJOL)

    Netherlands Liaison Office

    accessions were grouped into five marker based groups. This study proved that ..... contribute to the elucidation of forces that shape genetic ... Mathematical model for studying genetic variation in terms of ... WL, Lee M, Porter K (2000). Genetic ...

  9. The investigation of radiation induced defects in MgO

    International Nuclear Information System (INIS)

    Puetz, M.

    1990-05-01

    In this paper Frenkel defects were induced in MgO by 3 MeV electrons at low temperature. These defects were investigated by measurements of the optical absorption, by investigating the lattice parameters and Huang diffuse scattering. (WL)

  10. Tables of the 3-j, 6-j, Fsub(k)-, Asub(k)-, Rsub(k)-, and Asub(kk)-coefficients for angular correlation measurements involving half integer spins up to 15/2 and transitions up to L = 3

    International Nuclear Information System (INIS)

    Gueven, H.H.; Kardon, B.; Seyfarth, H.

    1975-07-01

    Theoretical directional correlation coefficiencts are given as 3-j, 6-j, Fsub(k), Asub(k), Rsub(k) and Asub(kk) coefficients for half integer spins up to 15/2 and for transitions up to L = 3. (WL) [de

  11. DNA markers reveal genetic structure and localized diversity of ...

    African Journals Online (AJOL)

    uqhdesma

    2016-10-12

    Oct 12, 2016 ... STRUCTURE analysis revealed 4 clusters of genetically ..... 10000 cycles and 50000 Markov Chain Monte Carlo (MCMC) iterations and 10 replicate runs performed for each K value to ..... WL, Lee M, Porter K (2000). Genetic ...

  12. Compensatory mechanisms activated with intermittent energy restriction

    DEFF Research Database (Denmark)

    Coutinho, Sílvia Ribeiro; Halset, Eline Holli; Gåsbakk, Sigrid

    2018-01-01

    Background & aims: Strong compensatory responses, with reduced resting metabolic rate (RMR), increased exercise efficiency (ExEff) and appetite, are activated when weight loss (WL) is achieved with continuous energy restriction (CER), which try to restore energy balance. Intermittent energy...... restriction (IER), where short spells of energy restriction are interspaced by periods of habitual energy intake, may offer some protection in minimizing those responses. We aimed to compare the effect of IER versus CER on body composition and the compensatory responses induced by WL. Methods: 35 adults (age......: 39 ± 9 y) with obesity (BMI: 36 ± 4 kg/m2) were randomized to lose a similar weight with an IER (N = 18) or a CER (N = 17) diet over a 12 week period. Macronutrient composition and overall energy restriction (33% reduction) were similar between groups. Body weight/composition, RMR, fasting...

  13. Morphometric evaluation of Arbor Acre parent stock broilers reared ...

    African Journals Online (AJOL)

    Morphometric evaluation of Arbor Acre parent stock broilers reared in ... Economic importance of morphometric parameters such as live weight and body ... (R2) value of 60.30 included forecast indices such as BL, WS, WL, TL, BG and SL.

  14. jfewr ©2016 - jfewr Publications

    African Journals Online (AJOL)

    OMERJI

    Using the equation K= 100W/L. 3 ... regions of Nigeria, there was no statistical significant difference (p>0.05) among the features between the strains of .... statistics using Genstat® discovery edition 12 as ..... (Hamilton 1822) using multivariate.

  15. An evaluation of the effect of land use/cover change on the surface ...

    African Journals Online (AJOL)

    user

    sity; poor water and soil quality; increased runoff and sedimentation ..... A conceptual framework for the study of human ecosystems in urban areas. - Urban Ecosyst. 1(4): 185-199. Steffen WL, Walker BH, Ingram JS, Koch GW (1992). Global ...

  16. Cosmology and galaxy formation

    International Nuclear Information System (INIS)

    Jones, B.J.T.; Gonzalez, E.M.

    1985-05-01

    The aim of the present series of lectures is to be unashamedly pedagogical and present, in simple terms, an overview of our current thinking about our universe and the way in which we believe galaxies have formed. (orig./WL)

  17. Assessment of the genetic diversity and pattern of relationship of ...

    African Journals Online (AJOL)

    SAM

    2014-04-02

    Apr 2, 2014 ... Cluster and principal coordinate analysis of the 30 ... The FST value (0.63) indicated a very high genetic differentiation as expected for ..... diversity) using Markov chain method showed that the ..... WL, Lee M, Porter K (2000).

  18. Proceedings of the third specialists' workshop on modeling tritium behaviour in ceramic fusion blankets

    International Nuclear Information System (INIS)

    Werle, H.

    1991-08-01

    The third specialists' workshop on modeling tritium behaviour in ceramic fusion blankets, hosted by Kernforschungszentrum Karlsruhe, was held June 10-11, 1991. The workshop was coordinated through the IEA Annex II implementing agreement on 'Radiation damage in fusion materials'. (orig./WL)

  19. Excitation functions of the systems 12C+14C and 13C+12C

    International Nuclear Information System (INIS)

    Haindl, E.

    1975-01-01

    The excitation functions of the systems 12 C+ 14 C and 13 C+ 12 C are investigated for different exit channels. The excitation functions measured do not show correlated structures as in the system 12 C+ 12 C. (WL/AK) [de

  20. 40 CFR Appendix II to Part 280 - List of Agencies Designated To Receive Notifications

    Science.gov (United States)

    2010-07-01

    ..., Ground Water Section/Water Division, 1751 Congressman W.L. Dickinson Drive, Montgomery, Alabama 36130... of Environmental Regulation, Solid Waste Section, Twin Towers Office Building, 2600 Blair Stone Road...), Division of Environmental Management, Ground-Water Operations Branch, Department of Natural Resources and...

  1. Elastic and inelastic heavy ion scattering

    International Nuclear Information System (INIS)

    Toepffer, C.; University of the Witwatersrand, Johannesburg; Richter, A.

    1977-02-01

    In the field of elastic and inelastic heavy ion scattering, the following issues are dealt with: semiclassical descriptive approximations, optical potentials, barriers, critical radii and angular momenta, excitation functions and the application to superheavy ions and high energies. (WL) [de

  2. Hepatitis C virus infection in nephrology patients

    African Journals Online (AJOL)

    Lionel Rostaing

    diabetic patients.35 The mechanism of this observation is unknown. 5. Diagnosis ..... et al. reviewed two meta-analyses (Meta-1 and Meta-2) pub- lished in 2008. From these .... Sabry AA, Sobh MA, Irving WL, et al. A comprehensive study of.

  3. Use of a microprocessor in a remote working level monitor

    International Nuclear Information System (INIS)

    Keffe, D.J.; McDowell, W.P.; Groer, P.G.

    1975-01-01

    A remote working level monitor was designed to measure short-lived radon-daughter concentrations in sealed chambers having potentially high radiation levels (up to 2000 WL). The system is comprised of surface barrier detectors, multiplexer and buffers, microprocessor and teletype

  4. Biological and technological effects of some mulberry varieties and ...

    African Journals Online (AJOL)

    egyptian hak

    Since the introduction of the Green Revolution in Asia, cultivation of ... Although meat is known to have a high Zn concentration, it is not readily ..... WL & Norvell WA (1978) Development of DTPA soil test for zinc, iron, manganese and copper.

  5. Making Sense of Formalization in Interorganizational Relationships: Beyond Coordination and Control

    NARCIS (Netherlands)

    P.W.L. Vlaar (Paul)

    2006-01-01

    textabstractPaul W.L. Vlaar (Obdam, January 4, 1978) obtained his M.Sc. degree in Economics (Cum Laude) from Wageningen University, The Netherlands. He is currently an assistant professor of strategic management at RSM Erasmus University. His research interests include interorganizational

  6. Daily energy expenditure, physical activity, and weight loss in Parkinson's disease patients

    Science.gov (United States)

    Patients with Parkinson's disease (PD) commonly exhibit weight loss (WL) which investigators attribute to various factors, including elevated energy expenditure. We tested the hypothesis that daily energy expenditure (DEE) and its components, resting energy expenditure (REE) and physical activity (P...

  7. Radon: Not so Noble

    Indian Academy of Sciences (India)

    Radon in the Environment and Associated Health Problems ... is presently working on emission of ... Radon isotope 222 has a half-life of 3.8 days, long enough to ..... 222Rn concentration of one WL for 170 working hours in one month.

  8. Dark Matter in Galaxy Clusters: Shape, Projection, and Environment

    Science.gov (United States)

    Groener, Austen M.

    We explore the intrinsic distribution of dark matter within galaxy clusters, by combining insights from the largest N-body simulations as well as the largest observational dataset of its kind. Firstly, we study the intrinsic shape and alignment of isodensities of galaxy cluster halos extracted from the MultiDark MDR1 cosmological simulation. We find that the simulated halos are extremely prolate on small scales and increasingly spherical on larger ones. Due to this trend, analytical projection along the line of sight produces an overestimate of the concentration index as a decreasing function of radius, which we quantify by using both the intrinsic distribution of 3D concentrations (c200) and isodensity shape on weak and strong lensing scales. We find this difference to be ˜ 18% (˜ 9%) for low (medium) mass cluster halos with intrinsically low concentrations (c200=1- 3), while we find virtually no difference for halos with intrinsically high concentrations. Isodensities are found to be fairly well-aligned throughout the entirety of the radial scale of each halo population. However, major axes of individual halos have been found to deviate by as much as ˜ 30°. We also present a value-added catalog of our analysis results, which we have made publicly available to download. Following that, we then turn to observational measurements galaxy clusters. Scaling relations of clusters have made them particularly important cosmological probes of structure formation. In this work, we present a comprehensive study of the relation between two profile observables, concentration (cvir ) and mass (Mvir). We have collected the largest known sample of measurements from the literature which make use of one or more of the following reconstruction techniques: Weak gravitational lensing (WL), strong gravitational lensing (SL), Weak+Strong Lensing (WL+SL), the Caustic Method (CM), Line-of-sight Velocity Dispersion (LOSVD), and X-ray. We find that the concentration-mass (c-M) relation

  9. A Randomized Controlled Trial of Cognitive-Behavior Therapy Plus Bright Light Therapy for Adolescent Delayed Sleep Phase Disorder

    Science.gov (United States)

    Gradisar, Michael; Dohnt, Hayley; Gardner, Greg; Paine, Sarah; Starkey, Karina; Menne, Annemarie; Slater, Amy; Wright, Helen; Hudson, Jennifer L.; Weaver, Edward; Trenowden, Sophie

    2011-01-01

    Objective: To evaluate cognitive-behavior therapy plus bright light therapy (CBT plus BLT) for adolescents diagnosed with delayed sleep phase disorder (DSPD). Design: Randomized controlled trial of CBT plus BLT vs. waitlist (WL) control with comparisons at pre- and post-treatment. There was 6-month follow-up for the CBT plus BLT group only. Setting: Flinders University Child & Adolescent Sleep Clinic, Adelaide, South Australia. Patients: 49 adolescents (mean age 14.6 ± 1.0 y, 53% males) diagnosed with DSPD; mean chronicity 4 y 8 months; 16% not attending school. Eighteen percent of adolescents dropped out of the study (CBT plus BLT: N = 23 vs WL: N = 17). Interventions: CBT plus BLT consisted of 6 individual sessions, including morning bright light therapy to advance adolescents' circadian rhythms, and cognitive restructuring and sleep education to target associated insomnia and sleep hygiene. Measurements and Results: DSPD diagnosis was performed via a clinical interview and 7-day sleep diary. Measurements at each time-point included online sleep diaries and scales measuring sleepiness, fatigue, and depression symptoms. Compared to WL, moderate-to-large improvements (d = 0.65-1.24) were found at post-treatment for CBT plus BLT adolescents, including reduced sleep latency, earlier sleep onset and rise times, total sleep time (school nights), wake after sleep onset, sleepiness, and fatigue. At 6-month follow-up (N = 15), small-to-large improvements (d = 0.24-1.53) continued for CBT plus BLT adolescents, with effects found for all measures. Significantly fewer adolescents receiving CBT plus BLT met DPSD criteria at post-treatment (WL = 82% vs. CBT plus BLT = 13%, P sleep and daytime impairments in the immediate and long-term. Studies evaluating the treatment effectiveness of each treatment component are needed. Clinical Trial Information: Australia – New Zealand Trials Registry Number: ACTRN12610001041044. Citation: Gradisar M; Dohnt H; Gardner G; Paine S; Starkey

  10. Formerly utilized MED/AEC sites remedial action program: radiological survey of the Building Site 421, United States, Watertown Arsenel, Watertown, MA. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-02-01

    This report contains the results of surveys of the current radiological condition of the Building Site 421, United States Arsenal Watertown, Watertown, Massachusetts. Findings of this survey indicate there are four spots involving an area of less than 6000 cm/sup 2/ of identifiable low-level residual radioactivity on the concrete pad which is all that remains of Building Site 421. The largest spot is approximately 5000 cm/sup 2/. The other three spots are 100 cm/sup 2/ or less. The beta-gamma readings at these spots are 8.4 x 10/sup 2/ dis/min-100 cm/sup 2/, 2.2 x 10/sup 5/ dis/min-100 cm/sup 2/, 2.2 x 10/sup 5/ dis/min-100 cm/sup 2/ and 8.5 x 10/sup 4/ dis/min-100 cm/sup 2/. No alpha contamination was found at these locations. Gamma spectral analysis of a chip of contaminated concrete from one of the spots indicates that the contaminant is natural uranium. This contamination is fixed in the concrete and does not present an internal or external exposure hazard under present conditions. A hypothetical hazard analysis under a conservative set of assumed conditions indicates minimal internal hazard. The highest End Window contact reading was 0.09 mR/h. None of the other three spots indicated an elevated direct reading with the End Window Detector. Radon daughter concentrations were determined at three locations on the Building 421 pad. These were 0.00013 WL, 0.00011 WL and 0.00009 WL. According to the Surgeon General's Guidelines found in 10 CFR 712, radon daughter concentrations below 0.03 WL do not require remedial action in structures other than private dwellings and schools. Soil samples taken about the site indicate no elevated levels above the natural background levels in the soil. A gamma spectral analysis of a water sample obtained from the storm sewer line near the Building 421 pad indicates no elevated radioactivity in the sample. It was therefore felt that no contamination is present in this sewer.

  11. SU-E-CAMPUS-T-01: Automation of the Winston-Lutz Test for Stereotactic Radiosurgery

    Energy Technology Data Exchange (ETDEWEB)

    Litzenberg, D; Irrer, J; Kessler, M; Lam, K [University of Michigan, Ann Arbor, MI (United States); Keranen, W [Varian Medical Systems, Inc., Palo Alto, CA (United States)

    2014-06-15

    Purpose: To optimize clinical efficiency and shorten patient wait time by minimizing the time and effort required to perform the Winston-Lutz test before stereotactic radiosurgery (SRS) through automation of the delivery, analysis, and documentation of results. Methods: The radiation fields of the Winston-Lutz (WL) test were created in a “machine-QA patient” saved in ARIA for use before SRS cases. Images of the BRW target ball placed at mechanical isocenter are captured with the portal imager for each of four, 2cm×2cm, MLC-shaped beams. When the WL plan is delivered and closed, this event is detected by in-house software called EventNet which automates subsequent processes with the aid of the ARIA web services. Images are automatically retrieved from the ARIA database and analyzed to determine the offset of the target ball from radiation isocenter. The results are posted to a website and a composite summary image of the results is pushed back into ImageBrowser for review and authenticated documentation. Results: The total time to perform the test was reduced from 20-25 minutes to less than 4 minutes. The results were found to be more accurate and consistent than the previous method which used radiochromic film. The images were also analyzed with DoseLab for comparison. The difference between the film and automated WL results in the X and Y direction and the radius were (−0.17 +/− 0.28) mm, (0.21 +/− 0.20) mm and (−0.14 +/− 0.27) mm, respectively. The difference between the DoseLab and automated WL results were (−0.05 +/− 0.06) mm, (−0.01 +/− 0.02) mm and (0.01 +/− 0.07) mm, respectively. Conclusions: This process reduced patient wait times by 15–20 minutes making the treatment machine available to treat another patient. Accuracy and consistency of results were improved over the previous method and were comparable to other commercial solutions. Access to the ARIA web services is made possible through an Eclipse co-development agreement

  12. Job Satisfaction: A Possible Integration of Two Theories

    Science.gov (United States)

    Hazer, John T.

    1976-01-01

    A rationale for deciding which motivation methods to use for employees who have differing levels of satisfaction. Discusses pros and cons of two theories on job satisfaction--Herzberg's theory and the traditional theory--suggesting strongly a need to combine both ideas. (WL)

  13. A new million-channel analyzer for complex nuclear spectroscopy studies and its application in measurements of the β decay of 149Pr

    International Nuclear Information System (INIS)

    Tenten, W.

    1978-11-01

    A million-channel analyzer with CAMAC instrumentation and PDP-11 control computer was developed and tested using the case of the β decay of 149 Pr and the γ decays of 149 Nd. A level scheme for 149 Nd was developed. (WL) [de

  14. Coaching: Learning and Using Environment and Agent Models for Advice

    Science.gov (United States)

    2005-03-31

    indicate what section(s) of the thesis use that citation. Mazda Ahmadi, Abolfazl Keighobadi Lamjiri, Mayssam M. Nevisi, Jafar Habibi, and Kambiz...and W.L. Johnson. Animated agents for procedural training in virtual reality: Perception, cognition, and motor control. Applied Artificial Intelligence

  15. AFLP analysis among Ethiopian arabica coffee genotypes

    African Journals Online (AJOL)

    STORAGESEVER

    2008-09-17

    Sep 17, 2008 ... AFLP analysis. AFLP analysis was performed following the protocol of Vos et al. ... 72oC. All polymerase chain reactions (PCR) were perform- ... ACT/MseI-CAG showed the highest value for MI ..... WL, Lee M, Porter K (2000).

  16. Thoron and radon measurements in houses

    International Nuclear Information System (INIS)

    Gauthier, C.

    1980-01-01

    Studies were made to determine what effect thoron daughters have on radon working level measurements in occupied houses at Elliot Lake. The decay of radon daughters is faster than that of thoron daughters. Six hours after sampling radon daughters are no longer present on the filter, and essentially all alpha activity is due to thoron C in transient equilibrium with thoron B. The concentrations can be extrapolated back to the time of the Kuznetz count, and the WL overestimation due to the presence of thoron daughters calculated. It was found using this method that in 70 percent of the samples the thoron contribution was no more than one mWL equivalent, less than the statistical error in the estimation of working levels. Only in buildings with very low ventilation rates and large areas of exposed concrete may corrections for the presence of thoron be necessary

  17. Calibration of environmental monitors operating on time integrating principles for radon/thoron decay products

    International Nuclear Information System (INIS)

    Bigu, J.; Grenier, M.

    1982-03-01

    An environmental radiation monitor for radon decay products has been tested under laboratory controlled conditions. The instrument is of a quasi-time-integrating type and was tested in conjunction with a radon 'box' calibration facility. It has been found that the instrument appreciably underestimates the radon daughter Working Level (WL). This is attributed to plate-out of decay products in the monitor sampling head. The difference between monitor reading and the WL by grab-sampling was higher for low aerosol concentrations. Plate-out on the instrument detector and sampling head, and contamination effects have been observed for the thoron case. There is partial agreement between experimental results and theoretical expectation. The monitor is slow to react to sudden changes in radiation level. The instrument should prove quite useful in the routine monitoring of surface and underground environments provided some suggested changes in the instrument are introduced

  18. An Adaptive Noise Cancellation System Based on Linear and Widely Linear Complex Valued Least Mean Square Algorithms for Removing Electrooculography Artifacts from Electroencephalography Signals

    Directory of Open Access Journals (Sweden)

    Engin Cemal MENGÜÇ

    2018-03-01

    Full Text Available In this study, an adaptive noise cancellation (ANC system based on linear and widely linear (WL complex valued least mean square (LMS algorithms is designed for removing electrooculography (EOG artifacts from electroencephalography (EEG signals. The real valued EOG and EEG signals (Fp1 and Fp2 given in dataset are primarily expressed as a complex valued signal in the complex domain. Then, using the proposed ANC system, the EOG artifacts are eliminated in the complex domain from the EEG signals. Expression of these signals in the complex domain allows us to remove EOG artifacts from two EEG channels simultaneously. Moreover, in this study, it has been shown that the complex valued EEG signal exhibits noncircular behavior, and in the case, the WL-CLMS algorithm enhances the performance of the ANC system compared to real-valued LMS and CLMS algorithms. Simulation results support the proposed approach.

  19. Protein supplements after weight loss do not improve weight maintenance compared with recommended dietary protein intake despite beneficial effects on appetite sensation and energy expenditure

    DEFF Research Database (Denmark)

    Kjølbæk, Louise; Sørensen, Lone Brinkmann; Søndertoft, Nadja Buus

    2017-01-01

    Background: High-protein diets increase weight loss (WL) during energy restriction; therefore, it has been suggested that additional protein intake may improve weight maintenance (WM) after WL.Objective: We investigated the effect of protein supplements from either whey with or without calcium...... were performed to investigate diet-induced-thermogenesis (DIT) and appetite sensation. Compliance was tested by 24-h urinary nitrogen excretion.Results: A total of 151 participants completed the WM period. The control and 3 protein supplements did not result in different mean ± SD weight regains (whey.......58 ± 1.4 kg; and control: 1.74 ± 1.4 kg; P = 0.50) during WM. Changes in blood pressure and blood biochemistry were not different between groups. Compared with the control, protein supplementation resulted in higher DIT (∼30 kJ/2.5 h) and resting energy expenditure (243 kJ/d) and an anorexigenic appetite...

  20. Inhibition properties of self-assembled corrosion inhibitor talloil diethylenetriamine imidazoline for mild steel corrosion in chloride solution saturated with carbon dioxide

    International Nuclear Information System (INIS)

    Jevremović, Ivana; Singer, Marc; Nešić, Srđan; Mišković-Stanković, Vesna

    2013-01-01

    Highlights: •Corrosion inhibitor talloil diethylenetriamine imidazoline effectively protects mild steel from CO 2 corrosion. •Quartz crystal microbalance measurements were used to the investigate kinetics of corrosion inhibitor adsorption. •Adsorption of talloil diethylenetriamine imidazoline can be described by Langmuir adsorption isotherm. -- Abstract: The inhibition effect of talloil diethylenetriamine imidazoline (TOFA/DETA imidazoline) on corrosion of mild steel in chloride solutions saturated with CO 2 was investigated by weight loss measurements (WL) and atomic force microscopy (AFM). Adsorption mechanism and kinetics of self-assembled (TOFA/DETA imidazoline) monolayers formation on gold were studied using the quartz crystal microbalance measurements (QCM). WL and AFM results demonstrated that TOFA/DETA imidazoline can effectively protect mild steel surface from corrosion. QCM measurements shown that the adsorption of TOFA/DETA imidazoline onto gold follows Langmuir adsorption isotherm and further investigation of the adsorption process will be carried out on a corroding metal surface

  1. House characteristics associated with gamma radiation and radon daughter working levels in eastern Pennsylvania

    International Nuclear Information System (INIS)

    Stebbings, J.H.; Dignam, J.J.; Anast, G.A.; Reilly, M.A.; Gerusky, T.M.; Hartman, T.T.

    1988-01-01

    Working levels (WL) of radon daughters and γ measurements in basements are described for ∼ 1200 houses near the Reading Prong. House variables included condition and construction materials of basement floors and walls, basement heights and areas, heating systems, air conditioning, water supply, and presence of drains and sump pumps. WLs were poorly predicted by house characteristics or γ measurements, while γ levels were well predicted by house characteristics and WL. Factors predicting high γ levels tended to be associated with low WLs and vice versa. Dirt basement floors and fieldstone basement walls were strongly associated with high γ levels, as were poor wall conditions in multivariate analyses. Gamma levels were low in electrically heated homes. High WLs were strongly associated with electric heat, low WLs with basement walls of fieldstone and/or in poor condition. Large house volumes and well water supply were also associated with higher WLs. (author)

  2. Short- and Long-Term Effects of CBT-I in Groups for School-Age Children Suffering From Chronic Insomnia: The KiSS-Program.

    Science.gov (United States)

    Schlarb, Angelika A; Bihlmaier, Isabel; Velten-Schurian, Kerstin; Poets, Christian F; Hautzinger, Martin

    2018-01-01

    This intervention study evaluates the short- and long-term effects of cognitive behavior therapy for insomnia (CBT-I) in groups for school-age children and their parents, named the KiSS-program. CBT-I was implemented in three sessions for children and three sessions for parents. All in all, 112 children with chronic childhood insomnia were randomly assigned to a wait-list (WL) control or treatment condition. According to subjective measures as well as objective wrist actigraphy, children in the CBT-I condition reported greater improvements in sleep behavior immediately after the treatment compared to the WL group. Improvements in sleep behavior after CBT-I persisted over the 3-, 6-, and 12-month follow-up assessments. The present study is the first randomized controlled trial that provides evidence for the long-term effectiveness of CBT-I in treating school-age children with chronic insomnia.

  3. Inhalation hazards to uranium miners

    International Nuclear Information System (INIS)

    Cross, F.T.

    1987-01-01

    Using both large and small experimental animals, this project is investigating levels of uranium-mine air contaminants that produce respiratory system disease in miners. Lung cancer incidence and deaths from degenerative lung disease are significantly elevated among uranium miners, but the cause-effect relationships for these diseases are based on inadequate epidemiological data. This project identifies agents or combinations of agents (both chemical and radiological), and their exposure levels, that produce respiratory tract lesions, including respiratory epithelial carcinoma, pneumoconiosis, and emphysema. Histopathological data for 100-working-level (WL) exposure rates show a significant increase in lung tumor risk over 1000-WL exposure rates for comparable cumulative radon-daughter exposures. Exposure of rats to radon daughters and other contaminants continues; the exposure of beagle dogs to uranium ore dust alone was terminated. Renal function and hematology data on ore-dust-exposed dogs are reported. 1 figure, 5 tables

  4. Protection of workers inside a radioactive wastes storage tunnel

    International Nuclear Information System (INIS)

    Leung, J.K.C.

    1993-01-01

    A network of tunnels which is used to store medium to low activity radioactive wastes was being reinforced structurally. Some of the radioactive wastes have to be transported from one section of the tunnel to another during the construction. The major radionuclides contained in the wastes are 226 Ra, 232 Th, 147 Pm, 60 Co and 137 Cs, hence the main radiation hazards to the workers are the external γ irradiation, internal radon exposure and internal exposure due to contaminations. The highest γ dose rate was 1000 μGy hr -1 measured at 1 cm from a lightning conductor waste containing 226 Ra. Under the unventilated condition, the highest working level for 222 Rn and 220 Rn daughters was 7.8 WL and 1 WL respectively. This paper describes the protection advices and procedures implemented to lower the radiation hazard to the workers. (1 fig., 1 tab.)

  5. Automating the design of resection guides specific to patient anatomy in knee replacement surgery by enhanced 3D curvature and surface modeling of distal femur shape models.

    Science.gov (United States)

    Cerveri, Pietro; Manzotti, Alfonso; Confalonieri, Norberto; Baroni, Guido

    2014-12-01

    Personalized resection guides (PRG) have been recently proposed in the domain of knee replacement, demonstrating clinical outcome similar or even superior to both manual and navigated interventions. Among the mandatory pre-surgical steps for PRG prototyping, the measurement of clinical landmarks (CL) on the bony surfaces is recognized as a key issue due to lack of standardized methodologies, operator-dependent variability and time expenditure. In this paper, we focus on the reliability and repeatability of an anterior-posterior axis, also known as Whiteside line (WL), of the distal femur proposing automatic surface processing and modeling methods aimed at overcoming some of the major concerns related to the manual identification of such CL on 2D images and 3D models. We show that the measurement of WL, exploiting the principle of mean-shifting surface curvature, is highly repeatable and coherent with clinical knowledge. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Quantitative Proteomics of the Root of Transgenic Wheat Expressing TaBWPR-1.2 Genes in Response to Waterlogging

    Directory of Open Access Journals (Sweden)

    Emdadul Haque

    2014-11-01

    Full Text Available Once candidate genes are available, the application of genetic transformation plays a major part to study their function in plants for adaptation to respective environmental stresses, including waterlogging (WL. The introduction of stress-inducible genes into wheat remains difficult because of low transformation and plant regeneration efficiencies and expression variability and instability. Earlier, we found two cDNAs encoding WL stress-responsive wheat pathogenesis-related proteins 1.2 (TaBWPR-1.2, TaBWPR-1.2#2 and TaBWPR-1.2#13. Using microprojectile bombardment, both cDNAs were introduced into “Bobwhite”. Despite low transformation efficiency, four independent T2 homozygous lines for each gene were isolated, where transgenes were ubiquitously and variously expressed. The highest transgene expression was obtained in Ubi:TaBWPR-1.2#2 L#11a and Ubi:TaBWPR-1.2#13 L#4a. Using quantitative proteomics, the root proteins of L#11a were analyzed to explore possible physiological pathways regulated by TaBWPR-1.2 under normal and waterlogged conditions. In L#11a, the abundance of proteasome subunit alpha type-3 decreased under normal conditions, whereas that of ferredoxin precursor and elongation factor-2 increased under waterlogged conditions in comparison with normal plants. Proteomic results suggest that L#11a is one of the engineered wheat plants where TaBWPR-1.2#2 is most probably involved in proteolysis, protein synthesis and alteration in the energy pathway in root tissues via the above proteins in order to gain metabolic adjustment to WL.

  7. Radioactive waste management at AECL

    International Nuclear Information System (INIS)

    Gadsby, R.D.; Allan, C.J.

    2003-01-01

    AECL has maintained an active program in radioactive waste management since 1945, when the Canadian nuclear program commenced activities at the Chalk River Laboratories (CRL). Waste management activities have included operation of waste management storage and processing facilities at AECL's CRL and Whiteshell Laboratories (WL); operation of the Low Level Radioactive Waste Management Office on behalf of Natural Resources Canada to resolve historic radioactive waste problems (largely associated with radioactive ore recovery, transport and processing operations) that are the responsibility of the Federal Government; development of the concept and related technology for geological disposal of Canada's nuclear fuel waste; development of the Intrusion-Resistant Underground Structure (IRUS) disposal concept for low-level nuclear waste; development of dry storage technology for the interim storage of used fuel; and development and assessment of waste processing technology for application in CANDU nuclear power plants and at CRL and WL. Today these activities are continuing. In addition, AECL is: preparing to decommission the nuclear facilities at WL; carrying out a number of smaller decommissioning projects at CRL; putting in place projects to upgrade the low-level liquid waste processing capabilities of the CRL Waste Treatment Centre, recover and process highly active liquid wastes currently in storage, and recover, condition and improve the storage of selected fuel wastes currently stored in below-ground standpipes in the CRL waste management areas; and assessing options for additional remediation projects to improve the management of other wastes currently in storage and to address environmental contamination from past practices. (author)

  8. THE HEIGHT OF A WHITE-LIGHT FLARE AND ITS HARD X-RAY SOURCES

    Energy Technology Data Exchange (ETDEWEB)

    Martinez Oliveros, Juan-Carlos; Hudson, Hugh S.; Hurford, Gordon J.; Krucker, Saem; Lin, R. P. [Space Sciences Laboratory, UC Berkeley, Berkeley, CA 94720 (United States); Lindsey, Charles [North West Research Associates, CORA Division, Boulder, CO (United States); Couvidat, Sebastien; Schou, Jesper [W. W. Hansen Experimental Physics Laboratory, Stanford University, Stanford, CA (United States); Thompson, W. T. [Adnet Systems, Inc., NASA Goddard Space Flight Center, code 671, Greenbelt, MD (United States)

    2012-07-10

    We describe observations of a white-light (WL) flare (SOL2011-02-24T07:35:00, M3.5) close to the limb of the Sun, from which we obtain estimates of the heights of the optical continuum sources and those of the associated hard X-ray (HXR) sources. For this purpose, we use HXR images from the Reuven Ramaty High Energy Spectroscopic Imager and optical images at 6173 A from the Solar Dynamics Observatory. We find that the centroids of the impulsive-phase emissions in WL and HXRs (30-80 keV) match closely in central distance (angular displacement from Sun center), within uncertainties of order 0.''2. This directly implies a common source height for these radiations, strengthening the connection between visible flare continuum formation and the accelerated electrons. We also estimate the absolute heights of these emissions as vertical distances from Sun center. Such a direct estimation has not been done previously, to our knowledge. Using a simultaneous 195 Angstrom-Sign image from the Solar-Terrestrial RElations Observatory spacecraft to identify the heliographic coordinates of the flare footpoints, we determine mean heights above the photosphere (as normally defined; {tau} = 1 at 5000 A) of 305 {+-} 170 km and 195 {+-} 70 km, respectively, for the centroids of the HXR and WL footpoint sources of the flare. These heights are unexpectedly low in the atmosphere, and are consistent with the expected locations of {tau} = 1 for the 6173 Angstrom-Sign and the {approx}40 keV photons observed, respectively.

  9. Isolating active orogenic wedge deformation in the southern Subandes of Bolivia

    Science.gov (United States)

    Weiss, Jonathan R.; Brooks, Benjamin A.; Foster, James H.; Bevis, Michael; Echalar, Arturo; Caccamise, Dana; Heck, Jacob; Kendrick, Eric; Ahlgren, Kevin; Raleigh, David; Smalley, Robert; Vergani, Gustavo

    2016-08-01

    A new GPS-derived surface velocity field for the central Andean backarc permits an assessment of orogenic wedge deformation across the southern Subandes of Bolivia, where recent studies suggest that great earthquakes (>Mw 8) are possible. We find that the backarc is not isolated from the main plate boundary seismic cycle. Rather, signals from subduction zone earthquakes contaminate the velocity field at distances greater than 800 km from the Chile trench. Two new wedge-crossing velocity profiles, corrected for seasonal and earthquake affects, reveal distinct regions that reflect (1) locking of the main plate boundary across the high Andes, (2) the location of and loading rate at the back of orogenic wedge, and (3) an east flank velocity gradient indicative of décollement locking beneath the Subandes. Modeling of the Subandean portions of the profiles indicates along-strike variations in the décollement locked width (WL) and wedge loading rate; the northern wedge décollement has a WL of ~100 km while accumulating slip at a rate of ~14 mm/yr, whereas the southern wedge has a WL of ~61 km and a slip rate of ~7 mm/yr. When compared to Quaternary estimates of geologic shortening and evidence for Holocene internal wedge deformation, the new GPS-derived wedge loading rates may indicate that the southern wedge is experiencing a phase of thickening via reactivation of preexisting internal structures. In contrast, we suspect that the northern wedge is undergoing an accretion or widening phase primarily via slip on relatively young thrust-front faults.

  10. Pilot Study of a New Nonradioactive Surgical Guidance Technology for Locating Nonpalpable Breast Lesions.

    Science.gov (United States)

    Cox, Charles E; Garcia-Henriquez, Norbert; Glancy, M Jordan; Whitworth, Pat; Cox, John M; Themar-Geck, Melissa; Prati, Ronald; Jung, Michelle; Russell, Scott; Appleton, Kristie; King, Jeff; Shivers, Steven C

    2016-06-01

    The current technique for locating nonpalpable breast lesions is wire localization (WL). Radioactive seed localization and intraoperative ultrasound were developed to improve difficulties with WL. The SAVI SCOUT surgical guidance system was developed to improve these methods. The SCOUT system is a non-radioactive, FDA-cleared medical device that uses electromagnetic wave technology to provide real-time guidance during excisional breast procedures. Consenting patients underwent localization and excision using an implantable electromagnetic wave reflective device (reflector) and a detector handpiece with a console. Using image guidance, the reflector was placed up to 7 days before the surgical procedure. The primary end points of the study were successful reflector placement, localization, and retrieval. The secondary end points were percentage of clear margins, reexcision rates, days of placement before excision, and physician comparison with WL. This study analyzed 50 patients. The reflectors were placed under mammographic guidance (n = 18, 36 %) or ultrasound guidance (n = 32, 64 %). Of the 50 patients, 10 (20 %) underwent excisional biopsy and 40 (80 %) had a lumpectomy. The lesion and reflector were successfully removed in all 50 patients, and no adverse events occurred. Of the 41 patients who had in situ and/or invasive carcinoma identified, 38 (93 %) had clear margins and 3 (7 %) were recommended for reexcision. These data suggest that the SCOUT system is safe and effective for guiding the excision of nonpalpable breast lesions and a viable alternative to standard localization options. A larger prospective, multi-institution trial of SCOUT currently is underway to validate these findings.

  11. Effects of bleaching agents on human enamel light reflectance.

    Science.gov (United States)

    Markovic, Ljubisa; Fotouhi, Kasra; Lorenz, Heribert; Jordan, Rainer A; Gaengler, Peter; Zimmer, Stefan

    2010-01-01

    Tooth whitening has been associated with splitting-up chromogenic molecules by hydrogen peroxides. Though micromorphological alterations are well documented, little is known about optical changes as a function of shifting in wavelengths. Therefore, the aim of the current study was to measure reflectance changes after bleaching in vitro by using a spectrometer. Forty-eight enamel slabs (diameter = 5 mm) were prepared from the sound enamel of extracted human teeth that were: 1) fully impacted, 2) from juveniles ages 10 to 16 years, 3) from adults 35 to 45 years of age and 4) from seniors older than age 65. In all specimens, the baseline total reflectance measurement was performed with a computer-assisted spectrometer (Ocean Optics, Dunedin, FL, USA) within wavelengths (wl) from 430 nm to 800 nm. Four enamel samples of each age group were exposed to either 10% or 15% carbamide peroxide (Illuminé Home, Dentsply, Konstanz, Germany) or 35% hydrogen peroxide (Pola Office, SDI Limited, Victoria, Australia). After surface treatment, all slabs underwent total reflectance measurement again. Statistical analysis was calculated at wl 450, 500 and 750 nm using the Student's paired t-test and one-way variance analysis. Total reflectance significantly increased after bleaching at all enamel maturation stages, irrespective of the bleaching agent concentration, for wl 450 nm (blue) and 500 nm (green) with penamel from adults and seniors (pwhitening of the dental enamel works at different maturation stages, even in impacted teeth. This effect is irrespective of the bleaching protocol used and the bleaching agent concentration.

  12. Randomized Controlled Trial of SuperBetter, a Smartphone-Based/Internet-Based Self-Help Tool to Reduce Depressive Symptoms.

    Science.gov (United States)

    Roepke, Ann Marie; Jaffee, Sara R; Riffle, Olivia M; McGonigal, Jane; Broome, Rose; Maxwell, Bez

    2015-06-01

    Technological advances have sparked the development of computer- and smartphone-based self-help programs for depressed people, but these programs' efficacy is uncertain. This randomized controlled trial evaluated an intervention called SuperBetter (SB), which is accessed via smartphone and/or the SB Web site. Online, we recruited 283 adult iPhone(®) (Apple, Cupertino, CA) users with significant depression symptoms according to the Center for Epidemiological Studies Depression questionnaire (CES-D). They were randomly assigned to one of three conditions: (a) a version of SB using cognitive-behavioral therapy and positive psychotherapy strategies to target depression (CBT-PPT SB); (b) a general SB version focused on self-esteem and acceptance (General SB); or (c) a waiting list control group (WL). The two SB groups were instructed to use SB for 10 minutes daily for 1 month. All participants completed psychological distress and well-being measures online every 2 weeks through follow-up. An intent-to-treat analysis was conducted using hierarchical linear modeling. As hypothesized, SB participants achieved greater reductions in CES-D scores than WL participants by posttest (Cohen's d=0.67) and by follow-up (d=1.05). Contrary to prediction, CBT-PPT SB did not perform better than General SB; both versions of SB were more effective than the WL control. Differences between SB versions favored General SB but were not statistically significant. These large effect sizes should be interpreted cautiously in light of high attrition rates and the motivated, self-selected sample. Nonetheless, smartphone-based/Internet-based self-help may play an important role in treating depression.

  13. Comparison of emission properties of two homologous flares in AR 11283

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Yan; Jing, Ju; Wang, Shuo; Wang, Haimin, E-mail: yx2@njit.edu [Space Weather Research Lab, Center for Solar-Terrestrial Research, New Jersey Institute of Technology 323 Martin Luther King Boulevard, Newark, NJ 07102-1982 (United States)

    2014-05-20

    Large, complex, active regions may produce multiple flares within a certain period of one or two days. These flares could occur in the same location with similar morphologies, commonly referred to as 'homologous flares'. In 2011 September, active region NOAA 11283 produced a pair of homologous flares on the 6th and 7th, respectively. Both of them were white-light (WL) flares, as captured by the Helioseismic and Magnetic Imager (HMI) on board the Solar Dynamics Observatory in visible continuum at 6173 Å which is believed to originate from the deep solar atmosphere. We investigate the WL emission of these X-class flares with HMI's seeing-free imaging spectroscopy. The durations of impulsive peaks in the continuum are about 4 minutes. We compare the WL with hard X-ray (HXR) observations for the September 6 flare and find a good correlation between the continuum and HXR both spatially and temporally. In absence of RHESSI data during the second flare on September 7, the derivative of the GOES soft X-ray is used and also found to be well correlated temporally with the continuum. We measure the contrast enhancements, characteristic sizes, and HXR fluxes of the twin flares, which are similar for both flares, indicating analogous triggering and heating processes. However, the September 7 flare was associated with conspicuous sunquake signals whereas no seismic wave was detected during the flare on September 6. Therefore, this comparison suggests that the particle bombardment may not play a dominant role in producing the sunquake events studied in this paper.

  14. The Height of a White-Light Flare and its Hard X-Ray Sources

    Science.gov (United States)

    Oliveros, Juan-Carlos Martinez; Hudson, Hugh S.; Hurford, Gordon J.; Kriucker, Saem; Lin, R. P.; Lindsey, Charles; Couvidat, Sebastien; Schou, Jesper; Thompson, W. T.

    2012-01-01

    We describe observations of a white-light (WL) flare (SOL2011-02-24T07:35:00, M3.5) close to the limb of the Sun, from which we obtain estimates of the heights of the optical continuum sources and those of the associated hard X-ray (HXR) sources. For this purpose, we use HXR images from the Reuven Ramaty High Energy Spectroscopic Imager and optical images at 6173 Ang. from the Solar Dynamics Observatory.We find that the centroids of the impulsive-phase emissions in WL and HXRs (30 -80 keV) match closely in central distance (angular displacement from Sun center), within uncertainties of order 0".2. This directly implies a common source height for these radiations, strengthening the connection between visible flare continuum formation and the accelerated electrons. We also estimate the absolute heights of these emissions as vertical distances from Sun center. Such a direct estimation has not been done previously, to our knowledge. Using a simultaneous 195 Ang. image from the Solar-Terrestrial RElations Observatory spacecraft to identify the heliographic coordinates of the flare footpoints, we determine mean heights above the photosphere (as normally defined; tau = 1 at 5000 Ang.) of 305 +/- 170 km and 195 +/- 70 km, respectively, for the centroids of the HXR and WL footpoint sources of the flare. These heights are unexpectedly low in the atmosphere, and are consistent with the expected locations of tau = 1 for the 6173 Ang and the approx 40 keV photons observed, respectively.

  15. The gravitational wave experiment at the University of Rome

    International Nuclear Information System (INIS)

    Amaldi, E.

    1977-01-01

    The gravitational wave detection experiment of a coincidence operation of at least one Weber-type antenna at three institutions around the earth is described. The mass of each antenne is fixed at 5 tons and the temperature is about 3 mK. (WL) [de

  16. South African Medical Journal - Vol 78, No 8 (1990)

    African Journals Online (AJOL)

    A comparison of caesarean section rates in white nulliparous women in the private and public ... Book Reviews · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT ... P.B. Hesseling, W.L. Mouton, P.A. Henning, G.F. Kirsten, L.L. Spruyt, E.B. ...

  17. Recent performances of the multiple charged heavy-ion source - triple mafios

    International Nuclear Information System (INIS)

    Briand, P.; Chan-tung, N.; Geller, R.; Jacquot, B.

    1977-01-01

    The principle and the characteristics of the ion source are described. We also furnish upto date performances concerning ion currents, globale emittances of the beam as well as the emittances of Ar 1+ to Ar 10+ in the radial and axial planes. (orig./WL) [de

  18. 78 FR 79009 - Proposed Information Collection; Radiation Sampling and Exposure Records (Pertains to Underground...

    Science.gov (United States)

    2013-12-27

    ... soliciting comments concerning the proposed information collection for updating Radiation Sampling and... exposed with no adverse effects have been established and are expressed as working levels (WL). The... mandatory samplings. Records must include the sample date, location, and results, and must be retained at...

  19. The Gore-Tex prosthetic ligament as a salvage procedure in deficient knees

    NARCIS (Netherlands)

    Roolker, W.; Patt, T. W.; van Dijk, C. N.; Vegter, M.; Marti, R. K.

    2000-01-01

    The purpose of this study was to evaluate the results of prosthetic ligament replacement of the anterior cruciate ligament (ACL) or posterior cruciate ligament (PCL) with the Gore-Tex polytetrafluorethyene prosthesis (W.L. Gore and Co., Flagstaff, Ariz. ) in 52 patients (54 knees). All patients

  20. Implementation of an automated assessment system of the Winston-Lutz test based on the transformed generalized Hough; Implementacion de un sistema de evaluacion automatizada del test de Winston-Lutz basado en la transformada generalizada de Hough

    Energy Technology Data Exchange (ETDEWEB)

    Martin-Viera Cueto, J. A.; Moreno Saiz, C.; Benitez Villegas, E. M.; Fernandez Canadillas, M. J.; Caballero Lucena, E.; Cantero Carrillo, M.

    2013-07-01

    It has implemented a software tool based on the generalized Hough transform to automate the evaluation of test WL This method provides a quantitative evaluation of the test. It also eliminates the subjectivity of the evaluator which is an uncertainty of 0.3 mm. (Author)

  1. Experiments on neutron-proton and neutron-electron interaction

    International Nuclear Information System (INIS)

    Koester, L.

    1975-01-01

    The paper reports on zero-energy experiments with neutrons, protons and electrons with a wavelength that is considerably longer than the particle expansion. Scattering amplitudes are measured for the reactions n + p and n + e. A neutron gravity refractometer is used. (WL/AK) [de

  2. Status report 1973-74

    International Nuclear Information System (INIS)

    1975-12-01

    In the field of experimental nuclear physics, the following main issues are dealt with: electron scattering, Moessbauer spectroscopy, nuclear fission and heavy ion reactions. In theoretical nuclear physics, nuclear structures and models as well as some aspects of neutron stars are discussed. (WL) [de

  3. MAR Assessments Of The High Level Waste System Plan Revision 16

    International Nuclear Information System (INIS)

    Peeler, D.; Edwards, T.

    2011-01-01

    High-level waste (HLW) throughput (i.e., the amount of waste processed per unit of time) is primarily a function of two critical parameters: waste loading (WL) and melt rate. For the Defense Waste Processing Facility (DWPF), increasing HLW throughput would significantly reduce the overall mission life cycle costs for the Department of Energy (DOE). Significant increases in waste throughput have been achieved at DWPF since initial radioactive operations began in 1996. Key technical and operational initiatives that supported increased waste throughput included improvements in facility attainment, the Chemical Processing Cell (CPC) flowsheet, process control models and frit formulations. As a result of these key initiatives, DWPF increased WLs from a nominal 28% for Sludge Batch 2 (SB2) to ∼34 to 38% for SB3 through SB6 while maintaining or slightly improving canister fill times. Although considerable improvements in waste throughput have been obtained, future contractual waste loading targets are nominally 40%, while canister production rates are also expected to increase (to a rate of 325 to 400 canisters per year). Although implementation of bubblers have made a positive impact on increasing melt rate for recent sludge batches targeting WLs in the mid30s, higher WLs will ultimately make the feeds to DWPF more challenging to process. Savannah River Remediation (SRR) recently requested the Savannah River National Laboratory (SRNL) to perform a paper study assessment using future sludge projections to evaluate whether the current Process Composition Control System (PCCS) algorithms would provide projected operating windows to allow future contractual WL targets to be met. More specifically, the objective of this study was to evaluate future sludge batch projections (based on Revision 16 of the HLW Systems Plan) with respect to projected operating windows using current PCCS models and associated constraints. Based on the assessments, the waste loading interval over

  4. 20 months UNILAC - first experiments and results

    International Nuclear Information System (INIS)

    Schwalm, D.

    1978-01-01

    The first few results obtained with the UNILAC heavy ion accelerator are described in an elementary survey. The results pretain to the fields of solid state research, quasi-atoms, nuclear coulomb excitation, heavy ion fusion and superheavy elements, and deep inelastic heavy ion reactions. (WL) [de

  5. Body composition of freshwater Wallago attu in relation to body size ...

    African Journals Online (AJOL)

    User

    2011-05-16

    May 16, 2011 ... water content. There was no significant influence of sex on body composition of W. attu. .... determined in duplicate for each fish using 1 g sub samples in a ... fish was calculated using a formula K = 100 x W/L3 by the method.

  6. Circular planning and adaptive design strategies to recycle wasted landscapes : The per-urban territories of campania plain as a case study

    NARCIS (Netherlands)

    Amenta, L.; Formato, E.; Hein, Carola

    2016-01-01

    The Campania Region, in the South of Italy, is a territory where numerous Wasted Landscapes (WL) are recognisable, as the result of serious social
    and governmental problems.
    Through the last decades, many factors have been overlapping in this complex palimpsest: illegal developments and the

  7. Rise of plasma ghrelin with weight loss is not sustained during weight maintenance

    Science.gov (United States)

    Ghrelin is postulated to be an orexigenic signal that promotes weight regain after weight loss (WL). However, it is not known whether this putative effect of ghrelin is sustained after weight stabilization. The objective of this study was to investigate the relationship of plasma ghrelin concentrati...

  8. 40 CFR 282.50 - Alabama State-Administered Program.

    Science.gov (United States)

    2010-07-01

    ... financial responsibility for hazardous substance underground storage tank systems. (2) Statement of legal... administered by the Alabama Department of Environmental Management, was approved by EPA pursuant to 42 U.S.C... obtained from the Ground Water Branch, Alabama Department of Environmental Management, 1751 W.L. Dickinson...

  9. The Early Universe. Facts and fiction. 4. ed.

    International Nuclear Information System (INIS)

    Boerner, G.

    2003-01-01

    The following topics are covered in this completely new written textbook: The standard big bang model, thermodynamics of the Early universe, gauge theories and standard model, grand unification models, baryon synthesis, inflationary universe, dark matter and galaxy formation, evolution of small perturbations, non-linear structure formation (WL)

  10. Global Genomic Analysis of Prostate, Breast and Pancreatic Cancer

    Science.gov (United States)

    2012-10-01

    publications (Oliver et al., 2012, Heiser et al., 2012). Strikingly, the same gene sets were associated with response to multiple drugs...DNA methylation mapping of clinical samples at single-nucleotide resolution. Nat Methods. 2010 Feb;7(2):133-6. Heiser LM, Sadanandam A, Kuo WL, Benz

  11. Borel summability in the disorder parameter of the averaged Green's function for Gaussian disorder

    International Nuclear Information System (INIS)

    Constantinescu, F.; Kloeckner, K.; Scharffenberger, U.

    1985-01-01

    In this note we prove Borel summability in the disorder parameter of the averaged Green's function of tight binding models Hsub(v)=-Δ+V with Gaussian disorder. Using this, we can reconstruct the density of states rho(E)sub(γ) from the Borel sums. (orig./WL)

  12. Comparison of extraction protocols to determine differences in wine-extractable tannin and anthocyanin in Vitis vinifera L. cv. Shiraz and Cabernet Sauvignon grapes.

    Science.gov (United States)

    Bindon, Keren A; Kassara, Stella; Cynkar, Wieslawa U; Robinson, Ella M C; Scrimgeour, Neil; Smith, Paul A

    2014-05-21

    Cabernet Sauvignon and Shiraz grapes were sourced from different regions within Australia, and microvinified with a skin contact period of 6 days. Grape samples were extracted using two protocols: a 15% v/v ethanol, 10 g/L tartaric acid extract of gently crushed berries (wine-like, WL) and a 50% v/v ethanol, pH 2 extract of grape berry homogenate. It was found that in WL extracts, grape tannin and anthocyanin concentrations were strongly related to wine tannin, anthocyanin and color density achieved during the skin contact period. No relationship was observed for grape tannin concentration analyzed in homogenate extracts and wine tannin, but a strong, positive relationship was found for anthocyanin concentration. When the data obtained from homogenate extraction was treated separately by grape variety, a stronger relationship between grape and wine tannin concentration was observed. Tannin compositional analysis in wines indicated that higher tannin concentrations were due to the extraction of tannin of higher molecular mass during fermentation, most likely from grape skins.

  13. A controlled study of virtual reality exposure therapy for the fear of flying.

    Science.gov (United States)

    Rothbaum, B O; Hodges, L; Smith, S; Lee, J H; Price, L

    2000-12-01

    Fear of flying (FOF) affects an estimated 10-25% of the population. Patients with FOF (N = 49) were randomly assigned to virtual reality exposure (VRE) therapy, standard exposure (SE) therapy, or a wait-list (WL) control. Treatment consisted of 8 sessions over 6 weeks, with 4 sessions of anxiety management training followed by either exposure to a virtual airplane (VRE) or exposure to an actual airplane at the airport (SE). A posttreatment flight on a commercial airline measured participants' willingness to fly and anxiety during flight immediately after treatment. The results indicated that VRE and SE were both superior to WL, with no differences between VRE and SE. The gains observed in treatment were maintained at a 6-month follow up. By 6 months posttreatment, 93% of VRE participants and 93% of SE participants had flown. VRE therapy and SE therapy for treatment of FOF were unequivocally supported in this controlled study.

  14. Studies on magneto conductance of nickel substituted FeSi

    Science.gov (United States)

    Krishnan, M.; Mishra, Ashish; Singh, Durgesh; Yadam, Sankararao; Venkatesh, R.; Gangrade, Mohan; Ganesan, V.

    2018-02-01

    Structural and electrical transport properties of Nickel (Ni) doped FeSi at low temperatures in the presence of zero and high magnetic fields are investigated systematically and reported. FeSi is a material known for its high thermoelectric power. Metal-Insulator Transition in FeSi is always an exotic one with different ground states depending upon the substituent. Changes in Magneto Resistance (MR) at low temperatures are explained by invoking an interplay between Weak Localization (WL) and enhanced Electron-Electron Interaction (EEI) that evolved upon varying the nickel concentrations. Competing interactions between WL and EEI along with Kondo hybridization scenario may classify this system into an exotic one among doped semiconductors. Temperature dependent zero field resistivity is analyzed in the light of various scattering mechanism in different doping regimes at low temperatures. Different crossover regimes are explained by invoking carriers and magnetic moments induced by the Ni impurity in an otherwise non-magnetic Kondo Insulator (KI).

  15. Considerations for application of Si(Li) detectors in analyses of sub-keV, ion-induced x rays

    International Nuclear Information System (INIS)

    Musket, R.G.

    1985-01-01

    Spectroscopy of ion-induced x rays is commonly performed using lithium-drifted, silicon detectors, Si(Li), with beryllium windows. Strong absorption of x rays with energies below 1 keV occurs in even the thinnest commercially available beryllium windows and precludes useful analysis of sub-keV x rays. Access to the sub-keV x ray region can be achieved using windowless (WL) and ultra-thin-windowed (UTW) Si(Li) detectors. These detectors have been shown to be useful for spectroscopy of x rays with energies above approximately 200 eV. The properties of such detectors are reviewed with regard to analysis of ion-induced x rays. In particular, considerations of detection efficiency, output linearity, energy resolution, peak shapes, and vacuum requirements are presented. The use of ion excitation for determination of many detector properties serves to demonstrate the usefulness of WL and UTW detectors for the spectroscopy of sub-keV, ion-induced x rays. 23 refs., 4 figs

  16. Influence of borehole-eccentred tools on wireline and logging-while-drilling sonic logging measurements

    KAUST Repository

    Pardo, David

    2013-02-13

    We describe a numerical study to quantify the influence of tool-eccentricity on wireline (WL) and logging-while-drilling (LWD) sonic logging measurements. Simulations are performed with a height-polynomial-adaptive (hp) Fourier finite-element method that delivers highly accurate solutions of linear visco-elasto-acoustic problems in the frequency domain. The analysis focuses on WL instruments equipped with monopole or dipole sources and LWD instruments with monopole excitation. Analysis of the main propagation modes obtained from frequency dispersion curves indicates that the additional high-order modes arising as a result of borehole-eccentricity interfere with the main modes (i.e., Stoneley, pseudo-Rayleigh and flexural). This often modifies (decreases) the estimation of shear and compressional formation velocities, which should be corrected (increased) to account for borehole-eccentricity effects. Undesired interferences between different modes can occur at different frequencies depending upon the properties of the formation and fluid annulus size, which may difficult the estimation of the formation velocities. © 2013 European Association of Geoscientists & Engineers.

  17. Testing a generalized cubic Galileon gravity model with the Coma Cluster

    Energy Technology Data Exchange (ETDEWEB)

    Terukina, Ayumu; Yamamoto, Kazuhiro; Okabe, Nobuhiro [Department of Physical Sciences, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8526 (Japan); Matsushita, Kyoko; Sasaki, Toru, E-mail: telkina@theo.phys.sci.hiroshima-u.ac.jp, E-mail: kazuhiro@hiroshima-u.ac.jp, E-mail: okabe@hiroshima-u.ac.jp, E-mail: matusita@rs.kagu.tus.ac.jp, E-mail: j1213703@ed.tus.ac.jp [Department of Physics, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601 (Japan)

    2015-10-01

    We obtain a constraint on the parameters of a generalized cubic Galileon gravity model exhibiting the Vainshtein mechanism by using multi-wavelength observations of the Coma Cluster. The generalized cubic Galileon model is characterized by three parameters of the turning scale associated with the Vainshtein mechanism, and the amplitude of modifying a gravitational potential and a lensing potential. X-ray and Sunyaev-Zel'dovich (SZ) observations of the intra-cluster medium are sensitive to the gravitational potential, while the weak-lensing (WL) measurement is specified by the lensing potential. A joint fit of a complementary multi-wavelength dataset of X-ray, SZ and WL measurements enables us to simultaneously constrain these three parameters of the generalized cubic Galileon model for the first time. We also find a degeneracy between the cluster mass parameters and the gravitational modification parameters, which is influential in the limit of the weak screening of the fifth force.

  18. Behavioural consequences of visual deprivation occurring at hatch or in the early life of chickens

    DEFF Research Database (Denmark)

    Hocking, Paul M.; Haldane, Kirsty-Anne; Davidson, Emma M.

    2015-01-01

    characteristic behaviours of both blind and sighted birds. Individual behaviour, group aggregation and behavioural synchrony were compared at 1, 5 and 9 weeks of age (experiment 1) and in the parents of these chicks at 9–13 months of age (experiment 2). Responses to visual and physical isolation were assessed...... at 1, 5 and 9 weeks. Analyses of home-pen behaviour showed that both rdd and beg had difficulty locating or consuming food during the first week of life. WL and rdd did not engage in abnormal behaviour (circle walking, air pecking, star gazing) at 1, 5 and 9 weeks whereas both beg and rdd adults did so...... visual isolation from conspecifics rdd chicks behaved like blind birds in some respects (e.g. decreased movement) and as sighted birds in others (e.g. peeping). The vision of rdd was apparently diminished compared with sighted controls (WL) even from an early age. It was concluded that abnormal...

  19. Comparison of a continuous working level monitor for radon daughters with conventional grab-sampling

    International Nuclear Information System (INIS)

    Bigu, J.; Grenier, M.

    1982-08-01

    An evaluation of a radon daughter monitor was carried out under laboratory controlled conditions. The monitor operates on continuous sampling and time integrating principles and was tested in conjunction with a newly designed, large radon/thoron room calibration facility. The monitor was tested under constant and rapidly fluctuating radiation conditions. Experimental data obtained with the monitor were compared with data obtained by conventional grab-sampling and with an automated radon daughter/thoron daughter 'grab-sampler'. The Working Level used in the tests ranged from less than 0.01 WL to approximately 10 WL. The measurements were carried out under low aerosol concentration (1 x 10 3 - 2 x 10 3 cm -3 , approximately) to study plate-out effects in the sampling head. Good agreement (within about 10 %) was found between the monitor, conventional grab-sampling and the automated grab-sampler. The monitor should prove quite flexible, useful and reliable for monitoring underground and surface environments in the uranium mining industry

  20. VUV photoemission studies of candidate LHC vacuum chamber materials

    CERN Document Server

    Baglin, V; Collins, I R

    1998-01-01

    In the context of future accelerators and, in particular, the beam vacuum of the LargeHadron Collider (LHC), a 27 km circumference proton collider to be built at CERN, VUVsynchrotron radiation (SR) has been used to study both qualitatively and quantitatively candidatevacuum chamber materials. Emphasis is given to show that angle and energy resolvedphotoemission is an extremely powerful tool to address important issues relevant to the LHC, suchas the emission of electrons that contribute to the creation of an electron cloud which may causeserious beam instabilities. Here we present not only the measured photoelectron yields (PY)from the proposed materials, prepared on an industrial scale, but also the energy and, in some cases,the angular dependence of the emitted electrons when excited with either a white light (WL)spectrum, simulating that in the arcs of the LHC or monochromatic light in the photon energy rangeof interest. The effects on the materials examined of WL irradiation and/or ion sputtering,simulati...

  1. Leakage characterization of top select transistor for program disturbance optimization in 3D NAND flash

    Science.gov (United States)

    Zhang, Yu; Jin, Lei; Jiang, Dandan; Zou, Xingqi; Zhao, Zhiguo; Gao, Jing; Zeng, Ming; Zhou, Wenbin; Tang, Zhaoyun; Huo, Zongliang

    2018-03-01

    In order to optimize program disturbance characteristics effectively, a characterization approach that measures top select transistor (TSG) leakage from bit-line is proposed to quantify TSG leakage under program inhibit condition in 3D NAND flash memory. Based on this approach, the effect of Vth modulation of two-cell TSG on leakage is evaluated. By checking the dependence of leakage and corresponding program disturbance on upper and lower TSG Vth, this approach is validated. The optimal Vth pattern with high upper TSG Vth and low lower TSG Vth has been suggested for low leakage current and high boosted channel potential. It is found that upper TSG plays dominant role in preventing drain induced barrier lowering (DIBL) leakage from boosted channel to bit-line, while lower TSG assists to further suppress TSG leakage by providing smooth potential drop from dummy WL to edge of TSG, consequently suppressing trap assisted band-to-band tunneling current (BTBT) between dummy WL and TSG.

  2. Indoor radon and its progeny levels in new type houses in rural area of Hubei

    International Nuclear Information System (INIS)

    He Quan; Xiong Zhaoxing; He Zuan; Zheng Youqing

    1993-01-01

    Using Cluster Sampling method, indoor radon of 54 rooms and radon progeny potential alpha-energy concentrations of 200 rooms were measured in the new type brick-concrete 2-storey flats and old type brick-wood single-storey residences in the rural area. Instant and cumulative samplings and measurements were made. The average per capita residential area of the surveyed houses was 28.1 m 2 , clear height 3.6 m. The geometric means of indoor radon concentration were 18.22 Bq.m -3 and 15.93 Bq.m -3 for storied and single-storey buildings, respectively; radon progeny potential alpha-energy concentrations were 2.62 mWL and 2.54 mWL, correspondingly. In storied buildings, the arithmetic mean of indoor cumulative radon concentration was 25.56 Bq.m -3 in summer, and 37.94 Bq.m -3 in winter. The annual effective dose equivalent of radon progeny inhaled indoors and outdoors was 0.80 mSv. (orig.). (6 refs., 1 fig., 5 tabs.)

  3. Bias due to selective dichotomization of multilevel exposure classes in risk analysis studies

    International Nuclear Information System (INIS)

    Peralta, S.B.

    1992-01-01

    General equations are developed for odds and risk ratio calculation in risk analysis studies with multiple exposure metrics, specifically for the four-level Wertheimer-Leeper (WL) code used in electromagnetic field (EMF) health studies. For an m-level code there are m-1 ways of categorizing subjects as exposed or unexposed: this dichotomization may be biased to maximize (or minimize) the risk parameter. This result is illustrated using Monte-Carlo simulation of health data. Results vary depending on the dichotomy used: indications of increased risk, decreased risk, window effects and inverse window effects are obtained, reflecting the range of conflicting results found in present-day EMF research. These results stress the need for care in the presentation and interpretation of health data in risk studies, especially where the exposure classification system is arbitrarily modifiable. This indication is especially urgent in the EMF field in view of recent proposals to base new epidemiological studies on subjectively modified WL codes. 8 refs., 7 tabs

  4. Tungsten and carbon surface change under high dose plasma exposure

    International Nuclear Information System (INIS)

    Martynenko, Y.V.; Khripunov, B.I.; Petrov, V.B.

    2009-01-01

    Study of surface composition dynamics has been made on the LENTA linear plasma simulator. Experiments have been made on tungsten and carbon materials subjected to steady-state plasma exposure. The achieved ion doses on the surface were 10 21 ion cm -2 . WL 10 tungsten containing 1% of La2O3 oxide and titanium-doped graphite RG-T were studied. The following experimental conditions were varied in these experiments: energy of ions, surface temperature, working gas. Irradiations of tungsten WL 10 were executed in deuterium plasma at low ion energies (about 20 eV) and at 200 eV for temperatures below 340 K. Graphite RG-T was exposed at 1300 K. Elevated surface temperature (about 1050K) was also characteristic of experiments on tungsten sample under nitrogen plasma impact (simulated inter-ELMs condition). Surface microstructure modification has been observed and surface composition changes were found on the materials showing influence of high dose plasma irradiations on element redistribution in the near surface layers. (author)

  5. A study of radon variation in dwelling during 1988

    International Nuclear Information System (INIS)

    Shaikh, A.N.; Ramachandran, T.V.; Muraleedharan, T.S.; Subbaramu, M.C.

    1989-01-01

    Natural radioactivity due to radon and its progeny levels indoors contributes significantly to the total radiation to man. The main source of radon and its progeny in a dwelling is the emanation of radon gas from soil. The temperature and ventilation vary in a dwelling during the year. These parameters influence the indoor radon levels. The seasonal variation of radon was studied in a dwelling as well as in the outside air. The filter paper method and alpha counting, and the solid state track detector technique and track counting were used to study the radon levels. The geometric mean of radon daughters concentrations were 0.5 mWL and 0.8 mWL measured by filter-paper method and SSNTD method respectively. The geometric mean of radon concentrations were 6.2 Bqm -3 and 10.0 Bqm -3 by filter-paper method and SSNTD method respectively. (author). 3 figs., 3 tabs., 13 refs

  6. Dose-dependent changes in renal {sup 1}H-/{sup 23}Na MRI after adjuvant radiochemotherapy for gastric cancer

    Energy Technology Data Exchange (ETDEWEB)

    Haneder, Stefan [University Medical Centre Mannheim, University of Heidelberg, Institute of Clinical Radiology and Nuclear Medicine, Mannheim (Germany); University Hospital of Cologne, Department of Radiology, Cologne (Germany); Budjan, Johannes Michael; Schoenberg, Stefan Oswald [University Medical Centre Mannheim, University of Heidelberg, Institute of Clinical Radiology and Nuclear Medicine, Mannheim (Germany); Konstandin, Simon; Schad, Lothar Rudi [University Medical Centre Mannheim, University of Heidelberg, Computer Assisted Clinical Medicine, Mannheim (Germany); Hofheinz, Ralf Dieter [University Medical Centre Mannheim, University of Heidelberg, III. Department of Internal Medicine, Mannheim (Germany); Gramlich, Veronika; Wenz, Frederik; Lohr, Frank; Boda-Heggemann, Judit [University Medical Centre Mannheim, Medical Faculty Mannheim - University of Heidelberg, Department of Radiation Oncology, Mannheim (Germany)

    2015-04-01

    Combined radiochemotherapy (RCT) for gastric cancer with three-dimensional conformal radiotherapy (3D-CRT) results in ablative doses to the upper left kidney, while image-guided intensity-modulated radiotherapy (IG-IMRT) allows kidney sparing despite improved target coverage. Renal function in long-term gastric cancer survivors was evaluated with 3T functional magnetic resonance imaging (MRI) including diffusion-weighted imaging (DWI) and {sup 23}Na imaging. Five healthy volunteers and 13 patients after radiotherapy were included: 11 x IG-IMRT; 1 x 3D-CRT; 1 x ''positive control'' with stereotactic body radiotherapy (SBRT) of a metastasis between the spleen/left kidney. Radiation doses were documented for the upper/middle/lower kidney subvolumes. Late toxicity was evaluated based on CTC criteria, questionnaire, and creatinine values. Morphological sequences, DWI images, and {sup 23}Na images were acquired using a {sup 1}H/{sup 23}Na-tuned body-coil before/after intravenous water load (WL). Statistics for [{sup 23}Na] (concentration) and apparent diffusion coefficient (ADC) values were calculated for upper/middle/lower renal subvolumes. Corticomedullary [{sup 23}Na] gradients and [{sup 23}Na] differences after WL were determined. No major morphological alteration was detected in any patient. Minor scars were observed in the cranial subvolume of the left kidney of the 3D-CRT and the whole kidney of the control SBRT patient. All participants presented a corticomedullary [{sup 23}Na] gradient. After WL, a significant physiological [{sup 23}Na] gradient decrease (p < 0.001) was observed in all HV and IG-IMRT patients. In the cranial left kidney of the 3D-CRT patient and the positive control SBRT patient, the decrease was nonsignificant (p = 0.01, p = 0.02). ADC values were altered nonsignificantly in all renal subvolumes (all participants). Renal subvolumes with doses ≥ 35 Gy showed a reduced change of the [{sup 23}Na] gradient after WL (p = 0

  7. Adequate formal language performance in unilateral cochlear implanted children: is it indicative of complete recovery in all linguistic domains? Insights from referential communication.

    Science.gov (United States)

    Mancini, Patrizia; Dincer D'Alessandro, Hilal; Guerzoni, Letizia; Cuda, Domenico; Ruoppolo, Giovanni; Musacchio, Angela; Di Mario, Alessia; De Seta, Elio; Bosco, Ersilia; Nicastri, Maria

    2015-04-01

    Referential communication (RC) is a key element in achieving a successful communication. This case series aimed to evaluate RC in children with unilateral cochlear implants (CIs) with formal language skills within the normal range. A total of 31 children with CIs, with language development within the normal range, were assessed using the Pragmatic Language Skills test (MEDEA). Of the children with CIs, 83.9% reached performance levels appropriate for their chronological ages. The results confirmed a positive effect of cochlear implantation on RC development, although difficulties remained in some CI users. The outcomes emphasize the need to pay greater attention to the pragmatic aspects of language, assessing them with adequate testing in the early phase after cochlear implantation. Clear knowledge of children's communicative competence is the key in optimizing their communicative environments in order to create the basis for future successful interpersonal exchanges and social integration. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  8. Identification of germline transcriptional regulatory elements in Aedes aegypti

    Science.gov (United States)

    Akbari, Omar S.; Papathanos, Philippos A.; Sandler, Jeremy E.; Kennedy, Katie; Hay, Bruce A.

    2014-02-01

    The mosquito Aedes aegypti is the principal vector for the yellow fever and dengue viruses, and is also responsible for recent outbreaks of the alphavirus chikungunya. Vector control strategies utilizing engineered gene drive systems are being developed as a means of replacing wild, pathogen transmitting mosquitoes with individuals refractory to disease transmission, or bringing about population suppression. Several of these systems, including Medea, UDMEL, and site-specific nucleases, which can be used to drive genes into populations or bring about population suppression, utilize transcriptional regulatory elements that drive germline-specific expression. Here we report the identification of multiple regulatory elements able to drive gene expression specifically in the female germline, or in the male and female germline, in the mosquito Aedes aegypti. These elements can also be used as tools with which to probe the roles of specific genes in germline function and in the early embryo, through overexpression or RNA interference.

  9. Cross-linguistic perspectives on the development of text-production abilities

    NARCIS (Netherlands)

    Berman, R.A.; Verhoeven, L.T.W.

    2002-01-01

    The studies reported in this volume of WL&L (5: 1–2, 2002) all derive from a joint project entitled “Developing literacy in different contexts and in different languages”, funded by the Spencer Foundation, Chicago. The study encompasses seven languages — Dutch, English, French, Hebrew, Icelandic,

  10. Water relations and transpiration of quinoa (Chenopodium quinoa Willd.) under salinity and soil drying

    DEFF Research Database (Denmark)

    Razzaghi, Fatemeh; Ahmadi, Seyed Hamid; Adolf, Verena Isabelle

    2011-01-01

    water potential (Wl), shoot and root abscisic acid concentration ([ABA]) and transpiration rate were measured in full irrigation (FI; around 95 % of water holding capacity (WHC)) and progressive drought (PD) treatments using the irrigation water with five salinity levels (0, 10, 20, 30 and 40 dS m)1...

  11. In vitro comparison of four different electronic apex locators to ...

    African Journals Online (AJOL)

    2014-04-14

    Apr 14, 2014 ... Materials and Methods: Forty-eight extracted single-rooted extracted teeth with ... increase postoperative pain and delay or prevent healing.[4] ... market to locate the root apex for measuring the WL such ... was used to check the canal patency. ... manufacturer's instructions for detecting the major foramen.

  12. Comparing Image Perception of Bladder Tumors in Four Different Storz Professional Image Enhancement System Modalities Using the íSPIES App

    NARCIS (Netherlands)

    Kamphuis, Guido M.; de Bruin, D. Martijn; Brandt, Martin J.; Knoll, Thomas; Conort, Pierre; Lapini, Alberto; Dominguez-Escrig, Jose L.; de La Rosette, Jean J. M. C. H.

    2016-01-01

    To evaluate the variation of interpretation of the same bladder urothelium image in different Storz Professional Image Enhancement System (SPIES) modalities. SPIES contains a White light (WL), Spectra A (SA), Spectra B (SB), and Clara and Chroma combined (CC) modality. An App for the iPAD retina was

  13. Sulphur oxidising bacteria in mangrove ecosystem: A review

    African Journals Online (AJOL)

    SAM

    2014-07-16

    Jul 16, 2014 ... factors such as salinity and nutrient availability highly variable. Mangrove .... sulphate and converts it into organic sulphur compound. (Subba Rao ..... of organic fertilizer long favored in Australia. .... Fish. Technol. Soc. 21:126-130. Dias ACF, Andreote FD, Rigonato J, Fiore MF, Melo IS, Araujo WL. (2010).

  14. A role for stomata in regulating water use efficiency in Populus x ...

    African Journals Online (AJOL)

    A role for stomata in regulating water use efficiency in Populus x euramericana and characterization of a related gene, PdERECTA. P Guo, X Xia, WL Yin. Abstract. The physiological mechanism of water use efficiency (WUE) remains elucidated, especially in poplar. We studied WUEi (instantaneous leaf transpiration ...

  15. Mutually Beneficial Service Learning: Language Teacher Candidates in a Local Community Center

    Science.gov (United States)

    Hildebrandt, Susan A.

    2014-01-01

    This article reports on a project designed to provide mutually beneficial solutions to challenges faced by world language teacher candidates, their preparation program, and a local community center. The project provided opportunities for teacher candidates enrolled in a world language (WL) teacher education course to complete clinical experiences…

  16. 2294-IJBCS-Article-Jacques Sawadogo

    African Journals Online (AJOL)

    hp

    2006-02-17

    Feb 17, 2006 ... conversion of solar energy into electric ..... File: L5b.RAW - Step: 0.020 ° - Step time: 15. s - Anode: Cu - WL1: 1.5406 - Generator kV: 40 kV - Generator mA: 40 mA - Divergence slit: ..... of quantum confinement on the electornic.

  17. Uranium City radiation reduction program: further efforts at remedial measures for houses with block walls, concrete porosity test results, and intercomparison of Kuznetz method and Tsivoglau method

    International Nuclear Information System (INIS)

    Haubrich, E.; Leung, M.K.; Mackie, R.

    1980-01-01

    An attempt was made to reduce the levels of radon in a house in Uranium City by mechanically venting the plenums in the concrete block basement walls, with little success. A table compares the results obtained by measuring the radon WL using the Tsivoglau and the Kuznetz methods

  18. Diet-induced weight loss decreases adipose tissue oxygen tension with parallel changes in adipose tissue phenotype and insulin sensitivity in overweight humans

    NARCIS (Netherlands)

    Vink, R.G.; Roumans, N.J.; Čajlaković, M.; Cleutjens, J.P.M.; Boekschoten, M.V.; Fazelzadeh, P.; Vogel, M.A.A.; Blaak, E.E.; Mariman, E.C.; Baak, van M.A.; Goossens, G.H.

    2017-01-01

    Background/objectives: Although adipose tissue (AT) hypoxia is present in rodent models of obesity, evidence for this in humans is limited. Here, we investigated the effects of diet-induced weight loss (WL) on abdominal subcutaneous AT oxygen tension (pO 2), AT blood flow (ATBF), AT capillary

  19. 76 FR 70921 - Implementation of the Fair Housing Act's Discriminatory Effects Standard

    Science.gov (United States)

    2011-11-16

    ... Housing Act complaints, recognizes the discriminatory effects theory of liability and requires HUD...) (``A violation of the [Act] may be premised on a theory of disparate impact.''); HUD v. Ross, 1994 WL 326437, at *5 (HUD ALJ July 7, 1994) (``Absent a showing of business necessity, facially neutral policies...

  20. Assessment of the Reliability of Concrete Slab Bridges

    DEFF Research Database (Denmark)

    Thoft-Christensen, Palle; Jensen, F. M.; Middleton, C. R.

    This paper is based on research performed for the Highways Agency, London, UK under the project DPU/9/44 "Revision of Bridge Assessment Rules Based on Whole Life Performance: Concrete Bridges". It contains details of a methodology which can be used to generate Whole Life (WL) reliability profiles....

  1. A Laser Technology Program Does Not Start with the Speed of Light.

    Science.gov (United States)

    Gebert, John H.

    1982-01-01

    Describes the personnel, equipment, and facilities problems encountered by North Central Technical Institute in the development of a laser technician program, and the program's enrollment and job placement rates. Advocates financial support for such programs to meet the national demand for laser and other high technology personnel. (WL)

  2. GPS receiver phase biases estimable in PPP-RTK networks: dynamic characterization and impact analysis

    Science.gov (United States)

    Zhang, Baocheng; Liu, Teng; Yuan, Yunbin

    2018-06-01

    The integer ambiguity resolution enabled precise point positioning (PPP-RTK) has been proven advantageous in a wide range of applications. The realization of PPP-RTK concerns the isolation of satellite phase biases (SPBs) and other corrections from a network of Global Positioning System (GPS) reference receivers. This is generally based on Kalman filter in order to achieve real-time capability, in which proper modeling of the dynamics of various types of unknowns remains crucial. This paper seeks to gain insight into how to reasonably deal with the dynamic behavior of the estimable receiver phase biases (RPBs). Using dual-frequency GPS data collected at six colocated receivers over days 50-120 of 2015, we analyze the 30-s epoch-by-epoch estimates of L1 and wide-lane (WL) RPBs for each receiver pair. The dynamics observed in these estimates are a combined effect of three factors, namely the random measurement noise, the multipath and the ambient temperature. The first factor can be overcome by turning to a real-time filter and the second by considering the use of a sidereal filtering. The third factor has an effect only on the WL, and this effect appears to be linear. After accounting for these three factors, the low-pass-filtered, sidereal-filtered, epoch-by-epoch estimates of L1 RPBs follow a random walk process, whereas those of WL RPBs are constant over time. Properly modeling the dynamics of RPBs is vital, as it ensures the best convergence of the Kalman-filtered, between-satellite single-differenced SPB estimates to their correct values and, in turn, shortens the time-to-first-fix at user side.

  3. GPS receiver phase biases estimable in PPP-RTK networks: dynamic characterization and impact analysis

    Science.gov (United States)

    Zhang, Baocheng; Liu, Teng; Yuan, Yunbin

    2017-11-01

    The integer ambiguity resolution enabled precise point positioning (PPP-RTK) has been proven advantageous in a wide range of applications. The realization of PPP-RTK concerns the isolation of satellite phase biases (SPBs) and other corrections from a network of Global Positioning System (GPS) reference receivers. This is generally based on Kalman filter in order to achieve real-time capability, in which proper modeling of the dynamics of various types of unknowns remains crucial. This paper seeks to gain insight into how to reasonably deal with the dynamic behavior of the estimable receiver phase biases (RPBs). Using dual-frequency GPS data collected at six colocated receivers over days 50-120 of 2015, we analyze the 30-s epoch-by-epoch estimates of L1 and wide-lane (WL) RPBs for each receiver pair. The dynamics observed in these estimates are a combined effect of three factors, namely the random measurement noise, the multipath and the ambient temperature. The first factor can be overcome by turning to a real-time filter and the second by considering the use of a sidereal filtering. The third factor has an effect only on the WL, and this effect appears to be linear. After accounting for these three factors, the low-pass-filtered, sidereal-filtered, epoch-by-epoch estimates of L1 RPBs follow a random walk process, whereas those of WL RPBs are constant over time. Properly modeling the dynamics of RPBs is vital, as it ensures the best convergence of the Kalman-filtered, between-satellite single-differenced SPB estimates to their correct values and, in turn, shortens the time-to-first-fix at user side.

  4. Testing the lognormality of the galaxy and weak lensing convergence distributions from Dark Energy Survey maps

    International Nuclear Information System (INIS)

    Clerkin, L.; Kirk, D.; Manera, M.; Lahav, O.; Abdalla, F.

    2016-01-01

    It is well known that the probability distribution function (PDF) of galaxy density contrast is approximately lognormal; whether the PDF of mass fluctuations derived from weak lensing convergence (κWL) is lognormal is less well established. We derive PDFs of the galaxy and projected matter density distributions via the counts-in-cells (CiC) method. We use maps of galaxies and weak lensing convergence produced from the Dark Energy Survey Science Verification data over 139 deg"2. We test whether the underlying density contrast is well described by a lognormal distribution for the galaxies, the convergence and their joint PDF. We confirm that the galaxy density contrast distribution is well modelled by a lognormal PDF convolved with Poisson noise at angular scales from 10 to 40 arcmin (corresponding to physical scales of 3–10 Mpc). We note that as κWL is a weighted sum of the mass fluctuations along the line of sight, its PDF is expected to be only approximately lognormal. We find that the κWL distribution is well modelled by a lognormal PDF convolved with Gaussian shape noise at scales between 10 and 20 arcmin, with a best-fitting χ"2/dof of 1.11 compared to 1.84 for a Gaussian model, corresponding to p-values 0.35 and 0.07, respectively, at a scale of 10 arcmin. Above 20 arcmin a simple Gaussian model is sufficient. The joint PDF is also reasonably fitted by a bivariate lognormal. As a consistency check, we compare the variances derived from the lognormal modelling with those directly measured via CiC. Lastly, our methods are validated against maps from the MICE Grand Challenge N-body simulation.

  5. A Comparison of Apical Transportation in Severely Curved Canals Induced by Reciproc and BioRaCe Systems.

    Science.gov (United States)

    Nabavizadeh, Mohammadreza; Abbaszadegan, Abbas; Khojastepour, Leila; Amirhosseini, Mohsen; Kiani, Ebrahim

    2014-01-01

    Preserving the apical root structure during cleaning and shaping of the canal has always been a challenge in endodontics particularly when the root canals are curved. The purpose of this in vitro study was to compare the apical transportation induced by the Reciproc and BioRaCe rotary systems in preparing the mesiobuccal root canal of the human maxillary molars. The mesiobuccal canals of sixty extracted maxillary molars with curvature angle of 25˚-35˚ were selected and randomly assigned into two groups. Each canal was prepared by either Reciproc or BioRaCe rotary systems. A double-digital radiographic technique and AutoCAD software were used to compare the apical transportation at 0.5, 1, 2, 3, 4 and 5 mm distances from the working length (WL). The distance between the master apical rotary file and the initial K-file in the superimposed radiographs determined the amount of apical transportation. An independent t-test was used to compare the groups. The statistical significant level was set at 0.05. Apical transportation of the Reciproc group was significantly greater than the BioRaCe group in all distances (P<0.001). The maximum apical transportation occurred in the Reciproc group at 0.5 mm from the WL (0.048±0.0028 mm) and the minimum occurred for BioRaCe at 5 mm from the WL (0.010±0.0005 mm). The Reciproc system produced significantly more apical transportation than the BioRaCe, but this fact does not seem to negatively alter the clinical success or quality of root canal treatment.

  6. Melatonin modulates monochromatic light-induced melatonin receptor expression in the hypothalamus of chicks.

    Science.gov (United States)

    Zhang, Liwei; Chen, Funing; Cao, Jing; Dong, Yulan; Wang, Zixu; Chen, Yaoxing

    2017-09-01

    To study the mechanism of the effect of monochromatic light on physiological function in chicken, a total of 192 newly hatched chicks were randomly divided into intact, sham-operated and pinealectomy groups then exposed to white light (WL), red light (RL), green light (GL) and blue light (BL) using a light-emitting diode (LED) system for two weeks. At P14, the hypothalami were immediately collected for immunohistochemical staining of melatonin receptor subtypes (Mel1a and Mel1b) and detection of Mel1a and Mel1b expressions using RT-PCR and western blot. Immunohistochemical staining of the hypothalamus showed that the Mel1a-ir cells were distributed in the preoptic area (POA), nucleus preopticus periventricularis (POP) and suprachiasmatic nuclei (SCN), and the Mel1b-ir cells were presented in the POA and SCN. Analysis of RT-PCR and western blot showed that the mRNA and protein levels of Mel1a and Mel1b in the hypothalamus of chick exposed to GL were increased by 10.7-29.3%, 9.18-35.9% and 8.97-27.3% compared to those in the chicks exposed to WL (P=0.029-0.002), RL (P=0.027-0.001) and BL (P=0.038-0.007) in the intact group, respectively. After pinealectomy, however, these parameters decreased and there were no significant differences among the WL, RL, GL and BL groups. These findings suggested that melatonin plays a critical role in GL illumination-enhanced Mel1a and Mel1b expressions in the hypothalamus of chicks. Copyright © 2017 Elsevier GmbH. All rights reserved.

  7. Light quality affects flavonoid production and related gene expression in Cyclocarya paliurus.

    Science.gov (United States)

    Liu, Yang; Fang, Shengzuo; Yang, Wanxia; Shang, Xulan; Fu, Xiangxiang

    2018-02-01

    Understanding the responses of plant growth and secondary metabolites to differential light conditions is very important to optimize cultivation conditions of medicinal woody plants. As a highly valued and multiple function tree species, Cyclocarya paliurus is planted and managed for timber production and medical use. In this study, LED-based light including white light (WL), blue light (BL), red light (RL), and green light (GL) were used to affect leaf biomass production, flavonoid accumulation and related gene expression of one-year C. paliurus seedlings in controlled environments. After the treatments of 60 days, the highest leaf biomass appeared in the treatment of WL, while the lowest leaf biomass was found under GL. Compared to WL, the total flavonoid contents of C. paliurus leaves were significantly higher in BL, RL, and GL, but the highest values of selected flavonoids (kaempferol, isoquercitrin and quercetin) were observed under BL. Furthermore, the greatest yields of total and selected flavonoids in C. paliurus leaves per seedling were also achieved under BL, indicating that blue light was effective for inducing the production of flavonoids in C. paliurus leaves. Pearson's correlation analysis showed that there were significantly positive correlations between leaf flavonoid content and relative gene expression of key enzymes (phenylalanine ammonia lyase, PAL; 4-coumaroyl CoA-ligase, 4CL; and chalcone synthase, CHS) in the upstream, which converting phenylalanine into the flavonoid skeleton of tetrahydroxy chalcone. It is concluded that manipulating light quality may be potential mean to achieve the highest yields of flavonoids in C. paliurus cultivation, however this needs to be further verified by more field trials. Copyright © 2018 Elsevier B.V. All rights reserved.

  8. Reduction of extinction and reinstatement of cocaine seeking by wheel running in female rats.

    Science.gov (United States)

    Zlebnik, Natalie E; Anker, Justin J; Gliddon, Luke A; Carroll, Marilyn E

    2010-03-01

    Previous work has shown that wheel running reduced the maintenance of cocaine self-administration in rats. In the present study, the effect of wheel running on extinction and reinstatement of cocaine seeking was examined. Female rats were trained to run in a wheel during 6-h sessions, and they were then catheterized and placed in an operant conditioning chamber where they did not have access to the wheel but were allowed to self-administer iv cocaine. Subsequently, rats were divided into four groups and were tested on the extinction and reinstatement of cocaine seeking while they had varying access to a wheel in an adjoining compartment. The four groups were assigned to the following wheel access conditions: (1) wheel running during extinction and reinstatement (WER), (2) wheel running during extinction and a locked wheel during reinstatement (WE), (3) locked wheel during extinction and wheel running during reinstatement (WR), and (4) locked wheel during extinction and reinstatement (WL). WE and WR were retested later to examine the effect of one session of wheel access on cocaine-primed reinstatement. There were no group differences in wheel revolutions, in rate of acquisition of cocaine self-administration, or in responding during maintenance when there was no wheel access. However, during extinction, WE and WER responded less than WR and WL. WR and WER had lower cocaine-primed reinstatement than WE and WL. One session of wheel exposure in WE also suppressed cocaine-primed reinstatement. Wheel running immediately and effectively reduced cocaine-seeking behavior, but concurrent access to running was necessary. Thus, exercise is a useful and self-sustaining intervention to reduce cocaine-seeking behavior.

  9. Lower Limb Neuromuscular Asymmetry in Volleyball and Basketball Players

    Directory of Open Access Journals (Sweden)

    Fort-Vanmeerhaeghe Azahara

    2016-04-01

    Full Text Available The primary objective of the present study was to evaluate the agreement between the dominant leg (DL (determined subjectively and the stronger leg (SL (determined via a functional test in a group of basketball and volleyball players. The secondary objective was to calculate lower limb neuromuscular asymmetry when comparing the DL vs the non-dominant leg (NDL and the SL vs the weaker (WL leg in the whole group and when differentiating by sex. Seventy-nine male and female volleyball and basketball players (age: 23.7 ± 4.5 years performed three single-leg vertical countermovement jumps (SLVCJ on a contact mat. Vertical jump height and an inter-limb asymmetry index (ASI were determined. Only 32 (40% of the subjects had a concordance between the perception of their dominant leg and the limb reaching the highest jump height. Using the DL as the discriminating variable, significant (p<0.05 inter-limb differences were found in the total group of players. When comparing between sexes, significant differences (p<0.05 arose in the female group only. With regard to the WL vs. the SL, significant (p<0.05 differences were noted in the whole group and when stratified into males and females. The mean ASI ranged from 9.31% (males to 12.84% (females and from 10.49% (males to 14.26% (females, when comparing the DL vs. the NDL and the SL vs. the WL, respectively. Subjective expression of leg dominance cannot be used as a predictor of limb jump performance. Vertical jump asymmetry of 10-15% exists and this can be considered as a reference value for male and female basketball and volleyball players.

  10. Radioguided breast surgery for occult lesion localization – correlation between two methods

    Directory of Open Access Journals (Sweden)

    Gutfilen Bianca

    2008-08-01

    Full Text Available Abstract Background The detection of sub-clinical breast lesions has increased with screening mammography. Biopsy techniques can offer precision and agility in its execution, as well as patient comfort. This trial compares radioguided occult lesion localization (ROLL and wire-guided localization (WL of breast lesions. We investigate if a procedure at the ambulatorial level (ROLL could lead to a better aesthetic result and less postoperative pain. In addition, we intend to demonstrate the efficacy of radioguided localization and removal of occult breast lesions using radiopharmaceuticals injected directly into the lesions and correlate radiological and histopathological findings. Methods One hundred and twenty patients were randomized into two groups (59 WL and 61 ROLL. The patients were requested to score the cosmetic appearance of their breast after surgery, and a numerical rating scale was used to measure pain on the first postoperative day. Clearance margins were considered at ≥ 10 mm for invasive cancer, ≥ 5 mm for ductal carcinoma in situ, and ≥ 1 mm for benign disease. Patients were subsequently treated according to the definitive histological result. When appropriate, different statistical tests were used in order to test the significance between the two groups, considering a P value Results WL and ROLL located all the occult breast lesions successfully. In the ROLL group, the specimen volume was smaller and there were more cases with clear margins (P Conclusion ROLL is an effective method for the excision of non-palpable breast lesions. It enables more careful planning of the cutaneous incision, leading to better aesthetic results, less postoperative symptoms, and smaller volumes of excised tissue.

  11. Dose-dependent changes in renal 1H-/23Na MRI after adjuvant radiochemotherapy for gastric cancer

    International Nuclear Information System (INIS)

    Haneder, Stefan; Budjan, Johannes Michael; Schoenberg, Stefan Oswald; Konstandin, Simon; Schad, Lothar Rudi; Hofheinz, Ralf Dieter; Gramlich, Veronika; Wenz, Frederik; Lohr, Frank; Boda-Heggemann, Judit

    2015-01-01

    Combined radiochemotherapy (RCT) for gastric cancer with three-dimensional conformal radiotherapy (3D-CRT) results in ablative doses to the upper left kidney, while image-guided intensity-modulated radiotherapy (IG-IMRT) allows kidney sparing despite improved target coverage. Renal function in long-term gastric cancer survivors was evaluated with 3T functional magnetic resonance imaging (MRI) including diffusion-weighted imaging (DWI) and 23 Na imaging. Five healthy volunteers and 13 patients after radiotherapy were included: 11 x IG-IMRT; 1 x 3D-CRT; 1 x ''positive control'' with stereotactic body radiotherapy (SBRT) of a metastasis between the spleen/left kidney. Radiation doses were documented for the upper/middle/lower kidney subvolumes. Late toxicity was evaluated based on CTC criteria, questionnaire, and creatinine values. Morphological sequences, DWI images, and 23 Na images were acquired using a 1 H/ 23 Na-tuned body-coil before/after intravenous water load (WL). Statistics for [ 23 Na] (concentration) and apparent diffusion coefficient (ADC) values were calculated for upper/middle/lower renal subvolumes. Corticomedullary [ 23 Na] gradients and [ 23 Na] differences after WL were determined. No major morphological alteration was detected in any patient. Minor scars were observed in the cranial subvolume of the left kidney of the 3D-CRT and the whole kidney of the control SBRT patient. All participants presented a corticomedullary [ 23 Na] gradient. After WL, a significant physiological [ 23 Na] gradient decrease (p < 0.001) was observed in all HV and IG-IMRT patients. In the cranial left kidney of the 3D-CRT patient and the positive control SBRT patient, the decrease was nonsignificant (p = 0.01, p = 0.02). ADC values were altered nonsignificantly in all renal subvolumes (all participants). Renal subvolumes with doses ≥ 35 Gy showed a reduced change of the [ 23 Na] gradient after WL (p = 0.043). No participants showed clinical renal

  12. Green Care Farms: An Innovative Type of Adult Day Service to Stimulate Social Participation of People With Dementia

    NARCIS (Netherlands)

    Bruin, de S.R.; Stoop, A.; Molema, C.C.M.; Vaandrager, L.; Hop, P.J.W.M.; Baan, C.A.

    2015-01-01

    Objective: To explore the value of day services at green care farms (GCFs) in terms of social participation for people with dementia. Method: Semi-structured interviews were conducted with people with dementia who attended day services at a GCF (GCF group, n = 21), were on a waiting list (WL) for

  13. A Randomized Controlled Trial of a Parent Training and Emotion Socialization Program for Families of Hyperactive Preschool-Aged Children

    Science.gov (United States)

    Herbert, Sharonne D.; Harvey, Elizabeth A.; Roberts, Jasmin L.; Wichowski, Kayla; Lugo-Candelas, Claudia I.

    2013-01-01

    The present study evaluated the effectiveness of a parent training and emotion socialization program designed specifically for hyperactive preschoolers. Participants were 31 preschool-aged children whose parents were randomly assigned to a parent training (PT) or waitlist (WL) control group. PT parents took part in a 14-week parenting program that…

  14. Accuracy of working length determination with root ZX apex locator ...

    African Journals Online (AJOL)

    The purpose of this study was to clinically compare working length (WL) determination with root ZX apex locator and radiography, and then compare them with direct visualization method ex vivo. A total of 75 maxillary central and lateral incisors were selected. Working length determination was carried out using radiographic ...

  15. Collinear laser spectroscopy on In isotopes from heavy ion fusion reactions

    International Nuclear Information System (INIS)

    Ulm, G.

    1984-07-01

    Indium isotopes 107-111 were produced by 16 O-fusion reactions and investigated in a collinear laser geometry. The hyperfine structure and isotopic shifts are measured and the deduced magnetic dipole moments are in agreement with shell model calculations. The nuclear charge radii are determined from the isotopic shifts. (WL)

  16. Author Details

    African Journals Online (AJOL)

    Jungers, WL. Vol 1, No 1 (2006) - Articles Preserving Madagascar's Natural Heritage: The Importance of Keeping the Island's Vertebrate Fossils in the Public Domain Abstract PDF. ISSN: 1662-2510. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

  17. The large-scale vented combustion test facility at AECL-WL: description and preliminary test results

    International Nuclear Information System (INIS)

    Loesel Sitar, J.; Koroll, G.W.; Dewit, W.A.; Bowles, E.M.; Harding, J.; Sabanski, C.L.; Kumar, R.K.

    1997-01-01

    Implementation of hydrogen mitigation systems in nuclear reactor containments requires testing the effectiveness of the mitigation system, reliability and availability of the hardware, potential consequences of its use and the technical basis for hardware placement, on a meaningful scale. Similarly, the development and validation of containment codes used in nuclear reactor safety analysis require detailed combustion data from medium- and large-scale facilities. A Large-Scale Combustion Test Facility measuring 10 m x 4 m x 3 m (volume, 120 m 3 ) has been constructed and commissioned at Whiteshell Laboratories to perform a wide variety of combustion experiments. The facility is designed to be versatile so that many geometrical configurations can be achieved. The facility incorporates extensive capabilities for instrumentation and high speed data acquisition, on-line gas sampling and analysis. Other features of the facility include operation at elevated temperatures up to 150 degrees C, easy access to the interior, and remote operation. Initial thermodynamic conditions in the facility can be controlled to within 0.1 vol% of constituent gases. The first series of experiments examined vented combustion in the full 120 m 3 -volume configuration with vent areas in the range of 0.56 to 2.24 m 2 . The experiments were performed at ∼27 degrees C and near-atmospheric pressures, with hydrogen concentrations in the range of 8 to 12% by volume. This paper describes the Large-Scale Vented Combustion Test Facility and preliminary results from the first series of experiments. (author)

  18. The most direct and precise radiocarbon date for the Minoan eruption of Santorini

    DEFF Research Database (Denmark)

    Friedrich, Walter L.; Heinemeier, Jan

    for the Minoan eruption. Together with a second olive tree, excavated only 9 meters from the first one, it enables us to repeat the earlier measurements of the first tree 2006 (Friedrich, W.L . Kromer, B Friedrich, M. Heinemeier, J. Pfeiffer, T. Talamo, S. Santorini Eruption Radiocarbon Dated to 1627-1600 BC...

  19. Planck intermediate results: III. the relation between galaxy cluster mass and Sunyaev-Zeldovich signal

    DEFF Research Database (Denmark)

    Bartlett, J.G.; Bucher, M.; Cardoso, J.-F.

    2013-01-01

    We examine the relation between the galaxy cluster mass M and Sunyaev-Zeldovich (SZ) effect signal DA2 Y500 for a sample of 19 objects for which weak lensing (WL) mass measurements obtained from Subaru Telescope data are available in the literature. Hydrostatic X-ray masses are derived from XMM-N...

  20. Scientific annual report 1972

    International Nuclear Information System (INIS)

    This is a report on scientific research at DESY in 1972. The activities in the field of electron-nucleon scattering, photoproduction and synchrotron radiation get a special mention. It is also reported on the work on the double storage ring as well as on the extension to the synchrotron. (WL/LN) [de

  1. A Randomised Controlled Trial of Two Early Intervention Programs for Young Children with Autism: Centre-Based with Parent Program and Home-Based

    Science.gov (United States)

    Roberts, Jacqueline; Williams, Katrina; Carter, Mark; Evans, David; Parmenter, Trevor; Silove, Natalie; Clark, Trevor; Warren, Anthony

    2011-01-01

    This study compares outcomes of early intervention programs for young children with autism; an individualised home-based program (HB), a small group centre-based program for children combined with a parent training and support group (CB) and a non-treatment comparison group (WL). Outcome measures of interest include social and communication skill…

  2. The quadriceps angle

    DEFF Research Database (Denmark)

    Miles, James Edward; Frederiksen, Jane V.; Jensen, Bente Rona

    2012-01-01

    : Pelvic limbs from red foxes (Vulpes vulpes). METHODS: Q angles were measured on hip dysplasia (HD) and whole limb (WL) view radiographs of each limb between the acetabular rim, mid-point (Q1: patellar center, Q2: femoral trochlea), and tibial tuberosity. Errors of 0.5-2.0 mm at measurement landmarks...

  3. Transport theory of deep-inelastic collisions between heavy nuclei

    International Nuclear Information System (INIS)

    Ayik, S.; Noerenberg, W.; Schuermann, B.

    1975-01-01

    In collisions between heavy nuclei, the major part of the total cross-section is due to deep-inelastic processes. These processes have been studied within a quantum-statistical approach leading to transport equations of the Fokker-Planck type (generalized diffusion equation). Transport coefficients have been studied within a model. (orig./WL) [de

  4. The scattering of polarized deuterons on 3He between 10 and 17 MeV

    International Nuclear Information System (INIS)

    Ohlsen, G.G.; Jarmie, N.; Haglund, R.H. Jr.; Brown, R.E.; Schmelzbach, P.A.

    1978-01-01

    Using the LASL polarized beam facility, the cross section and vector and tensor analysing powers for the 3 He(d vector,d) 3 He and 3 He(d vector,p) 4 He reactions have been measured in a large angular range at energies between 10 and 17 MeV. (orig./WL) [de

  5. Genetic fidelity in micropropagated plantlets of Ochreinauclea ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-07-06

    Jul 6, 2009 ... show the genetic similarity among the 22 plants (21 micropropagated plants and 1 donor mother plant). In the present study, ..... Determination of genetic stability in long-term micropropagated shoots of Pinus thunbergii Parl. using. RAPD markers. Plant Cell Rep. 18: 193-197. Guo WL, Gong L, Ding ZF, ...

  6. Er: YLF Laser Development

    Science.gov (United States)

    1975-12-01

    Force Wright Aeronautical Laboratory, AFAL/DHO, Wright-Patterson AFB, OH 45433. WL/AFSC( IST ) ltr, 12 Apr 1991 UNCLASSIFIED AD NUMBER LIMITATION CHANGES TO...ju^i^zs.^iu •Lbbrtbataafetiu.*. i ! mtotfffiflaiai WP1— 1 ’ »■■■«I HIU I I .1 III ll.lll. VIH IWII

  7. On the Relationships between Jeffreys Modal and Weighted Likelihood Estimation of Ability under Logistic IRT Models

    Science.gov (United States)

    Magis, David; Raiche, Gilles

    2012-01-01

    This paper focuses on two estimators of ability with logistic item response theory models: the Bayesian modal (BM) estimator and the weighted likelihood (WL) estimator. For the BM estimator, Jeffreys' prior distribution is considered, and the corresponding estimator is referred to as the Jeffreys modal (JM) estimator. It is established that under…

  8. Three novel antioxidants from Cinnamomum plants | Cheng | African ...

    African Journals Online (AJOL)

    Three novel antioxidants from Cinnamomum plants. K-C Cheng, H-A Chen, P-F Wu, W-L Yang, H-M Wang, C-Y Chen. Abstract. In this study, we identified three novel antioxidants, subamolide C (1), subamolide E (2) and isokotomolide A (3) from the constitutes of Cinnamomum subavenium and Cinnamomum kotoense.

  9. PREFACE: Euro-TMCS I: Theory, Modelling and Computational Methods for Semiconductors

    Science.gov (United States)

    Gómez-Campos, F. M.; Rodríguez-Bolívar, S.; Tomić, S.

    2015-05-01

    The present issue contains a selection of the best contributed works presented at the first Euro-TMCS conference (Theory, Modelling and Computational Methods for Semiconductors, European Session). The conference was held at Faculty of Sciences, Universidad de Granada, Spain on 28st-30st January 2015. This conference is the first European edition of the TMCS conference series which started in 2008 at the University of Manchester and has always been held in the United Kingdom. Four previous conferences have been previously carried out (Manchester 2008, York 2010, Leeds 2012 and Salford 2014). Euro-TMCS is run for three days; the first one devoted to giving invited tutorials, aimed particularly at students, on recent development of theoretical methods. On this occasion the session was focused on the presentation of widely-used computational methods for the modelling of physical processes in semiconductor materials. Freely available simulation software (SIESTA, Quantum Espresso and Yambo) as well as commercial software (TiberCad and MedeA) were presented in the conference by members of their development team, offering to the audience an overview of their capabilities for research. The second part of the conference showcased prestigious invited and contributed oral presentations, alongside poster sessions, in which direct discussion with authors was promoted. The scope of this conference embraces modelling, theory and the use of sophisticated computational tools in semiconductor science and technology. Theoretical approaches represented in this meeting included: Density Functional Theory, Semi-empirical Electronic Structure Methods, Multi-scale Approaches, Modelling of PV devices, Electron Transport, and Graphene. Topics included, but were not limited to: Optical Properties of Quantum Nanostructures including Colloids and Nanotubes, Plasmonics, Magnetic Semiconductors, Photonic Structures, and Electronic Devices. The Editors Acknowledgments: We would like to thank all

  10. MEASUREMENT OF WASTE LOADING IN SALTSTONE

    International Nuclear Information System (INIS)

    Harbour, J; Vickie Williams, V

    2008-01-01

    One of the goals of the Saltstone variability study is to identify the operational and compositional variables that control or influence the important processing and performance properties of Saltstone grout mixtures. One of those properties of importance is the Waste Loading (WL) of the decontaminated salt solution (DSS) in the Saltstone waste form. Waste loading is a measure of the amount of waste that can be incorporated within a waste form. The value of the Saltstone waste loading ultimately determines the number of vaults that will be required to disposition all of the DSS. In this report, the waste loading is defined as the volume in milliliters of DSS per liter of Saltstone waste form. The two most important parameters that determine waste loading for Saltstone are water to cementitious material (w/cm) ratio and the cured grout density. Data are provided that show the dependence of waste loading on the w/cm ratio for a fixed DSS composition using the current premix material (45% Blast Furnace Slag (BFS), 45% Fly Ash (FA) and 10% Ordinary Portland Cement (OPC)). The impact of cured grout density on waste loading was also demonstrated. Mixes (at 0.60 w/cm) made with a Modular Caustic side extraction Unit (MCU) simulant and either OPC or BFS have higher cured grout densities than mixes made with premix and increase the WL to 709 mL/L for the OPC mix and 689 mL/L for the BFS mix versus the value of 653 mL/L for MCU in premix at 0.60 w/cm ratio. Bleed liquid reduces the waste loading and lowers the effective w/cm ratio of Saltstone. A method is presented (and will be used in future tasks) for correcting the waste loading and the w/cm ratio of the as-batched mixes in those cases where bleed liquid is present. For example, the Deliquification, Dissolution and Adjustment (DDA) mix at an as-batched 0.60 w/cm ratio, when corrected for % bleed, gives a mix with a 0.55 w/cm ratio and a WL that has been reduced from 662 to 625 mL/L. An example is provided that

  11. Improving Ambiguity Resolution for Medium Baselines Using Combined GPS and BDS Dual/Triple-Frequency Observations.

    Science.gov (United States)

    Gao, Wang; Gao, Chengfa; Pan, Shuguo; Wang, Denghui; Deng, Jiadong

    2015-10-30

    The regional constellation of the BeiDou navigation satellite system (BDS) has been providing continuous positioning, navigation and timing services since 27 December 2012, covering China and the surrounding area. Real-time kinematic (RTK) positioning with combined BDS and GPS observations is feasible. Besides, all satellites of BDS can transmit triple-frequency signals. Using the advantages of multi-pseudorange and carrier observations from multi-systems and multi-frequencies is expected to be of much benefit for ambiguity resolution (AR). We propose an integrated AR strategy for medium baselines by using the combined GPS and BDS dual/triple-frequency observations. In the method, firstly the extra-wide-lane (EWL) ambiguities of triple-frequency system, i.e., BDS, are determined first. Then the dual-frequency WL ambiguities of BDS and GPS were resolved with the geometry-based model by using the BDS ambiguity-fixed EWL observations. After that, basic (i.e., L1/L2 or B1/B2) ambiguities of BDS and GPS are estimated together with the so-called ionosphere-constrained model, where the ambiguity-fixed WL observations are added to enhance the model strength. During both of the WL and basic AR, a partial ambiguity fixing (PAF) strategy is adopted to weaken the negative influence of new-rising or low-elevation satellites. Experiments were conducted and presented, in which the GPS/BDS dual/triple-frequency data were collected in Nanjing and Zhengzhou of China, with the baseline distance varying from about 28.6 to 51.9 km. The results indicate that, compared to the single triple-frequency BDS system, the combined system can significantly enhance the AR model strength, and thus improve AR performance for medium baselines with a 75.7% reduction of initialization time on average. Besides, more accurate and stable positioning results can also be derived by using the combined GPS/BDS system.

  12. The Effect of Traditional Cupping on Pain and Mechanical Thresholds in Patients with Chronic Nonspecific Neck Pain: A Randomised Controlled Pilot Study

    Directory of Open Access Journals (Sweden)

    Romy Lauche

    2012-01-01

    Full Text Available Introduction. Cupping has been used since antiquity in the treatment of pain conditions. In this pilot study, we investigated the effect of traditional cupping therapy on chronic nonspecific neck pain (CNP and mechanical sensory thresholds. Methods. Fifty CNP patients were randomly assigned to treatment (TG, n=25 or waiting list control group (WL, n=25. TG received a single cupping treatment. Pain at rest (PR, pain related to movement (PM, quality of life (SF-36, Neck Disability Index (NDI, mechanical detection (MDT, vibration detection (MDT, and pressure pain thresholds (PPT were measured before and three days after a single cupping treatment. Patients also kept a pain and medication diary (PaDi, MeDi during the study. Results. Baseline characteristics were similar in the two groups. After cupping TG reported significantly less pain (PR: −17.9 mm VAS, 95%CI −29.2 to −6.6; PM: −19.7, 95%CI −32.2 to −7.2; PaDi: −1.5 points on NRS, 95%CI −2.5 to −0.4; all P<0.05 and higher quality of life than WL (SF-36, Physical Functioning: 7.5, 95%CI 1.4 to 13.5; Bodily Pain: 14.9, 95%CI 4.4 to 25.4; Physical Component Score: 5.0, 95%CI 1.4 to 8.5; all P<0.05. No significant effect was found for NDI, MDT, or VDT, but TG showed significantly higher PPT at pain-areas than WL (in lg(kPa; pain-maximum: 0.088, 95%CI 0.029 to 0.148, pain-adjacent: 0.118, 95%CI 0.038 to 0.199; both P<0.01. Conclusion. A single application of traditional cupping might be an effective treatment for improving pain, quality of life, and hyperalgesia in CNP.

  13. Linseed Dietary Fibers Reduce Apparent Digestibility of Energy and Fat and Weight Gain in Growing Rats

    Directory of Open Access Journals (Sweden)

    Arne Astrup

    2013-08-01

    Full Text Available Dietary fibers (DF may affect energy balance, an effect often ascribed to the viscous nature of some water soluble DF, which affect luminal viscosity and thus multiple physiological processes. We have tested the hypothesis that viscous linseed DF reduce apparent nutrient digestibility, and limit weight gain, in a randomized feeding trial where 60 male, growing, Wistar rats, with an initial weight of ~200 g, were fed different diets (n = 10 per group: low DF control (C, 5% DF from cellulose (5-CEL, CEL + 5% DF from whole (5-WL or ground linseed (5-GL, CEL + 5% DF from linseed DF extract (5-LDF, and CEL + 10% DF from linseed DF extract (10-LDF. Diets were provided ad libitum for 21 days. Feed intake and faecal output were measured during days 17–21. Faecal fat excretion increased with increasing DF content and was highest in the 10-LDF group. Apparent fat digestibility was highest with the C diet (94.9% ± 0.8% and lowest (74.3% ± 0.6% with the 10-LDF diet, and decreased in a non-linear manner with increasing DF (p < 0.001. Apparent fat digestibility also decreased with increased accessibility of DF (5-WL vs. 5-GL and when the proportion of viscous DF increased (5-GL vs. 5-LDF. The 10-LDF resulted in a lower final body weight (258 ± 6.2 g compared to C (282 ± 5.9 g, 5-CEL (281 ± 5.9 g, and 5-WL (285 ± 5.9 g (p < 0.05. The 10-LDF diet reduced body fat compared to 5-CEL (p < 0.01. In conclusion, DF extracted from linseed reduced apparent energy and fat digestibility and resulted in restriction of body weight gain in growing rats.

  14. Leucine-rich diet alters the eukaryotic translation initiation factors expression in skeletal muscle of tumour-bearing rats

    Directory of Open Access Journals (Sweden)

    Mello Maria

    2007-03-01

    Full Text Available Abstract Background Cancer-cachexia induces a variety of metabolic disorders on protein turnorver, decreasing protein synthesis and increasing protein degradation. Controversly, insulin, other hormones, and branched-chain amino acids, especially leucine, stimulate protein synthesis and modulate the activity of translation initiation factors involved in protein synthesis. Since the tumour effects are more pronounced when associated with pregnancy, ehancing muscle-wasting proteolysis, in this study, the influence of a leucine-rich diet on the protein synthesis caused by cancer were investigated. Methods Pregnant rats with or without Walker 256 tumour were distributed into six groups. During 20 days of experiment, three groups were fed with a control diet: C – pregnant control, W – tumour-bearing, and P – pair-fed, which received the same amount of food as ingested by the W group; three other groups of pregnant rats were fed a leucine-rich diet: L – pregnant leucine, WL – tumour-bearing, and PL – pair-fed, which received the same amount of food as ingested by the WL group. Results The gastrocnemius muscle of WL rats showed increased incorporation of leucine in protein compared to W rats; the leucine-rich diet also prevented the decrease in plasma insulin normally seen in W. The expression of translation initiation factors increased when tumour-bearing rats fed leucine-rich diet, with increase of ~35% for eIF2α and eIF5, ~17% for eIF4E and 20% for eIF4G; the expression of protein kinase S6K1 and protein kinase C was also highly enhanced. Conclusion The results suggest that a leucine-rich diet increased the protein synthesis in skeletal muscle in tumour-bearing rats possibly through the activation of eIF factors and/or the S6kinase pathway.

  15. Leucine-rich diet alters the eukaryotic translation initiation factors expression in skeletal muscle of tumour-bearing rats

    International Nuclear Information System (INIS)

    Ventrucci, Gislaine; Mello, Maria Alice R; Gomes-Marcondes, Maria Cristina C

    2007-01-01

    Cancer-cachexia induces a variety of metabolic disorders on protein turnorver, decreasing protein synthesis and increasing protein degradation. Controversly, insulin, other hormones, and branched-chain amino acids, especially leucine, stimulate protein synthesis and modulate the activity of translation initiation factors involved in protein synthesis. Since the tumour effects are more pronounced when associated with pregnancy, ehancing muscle-wasting proteolysis, in this study, the influence of a leucine-rich diet on the protein synthesis caused by cancer were investigated. Pregnant rats with or without Walker 256 tumour were distributed into six groups. During 20 days of experiment, three groups were fed with a control diet: C – pregnant control, W – tumour-bearing, and P – pair-fed, which received the same amount of food as ingested by the W group; three other groups of pregnant rats were fed a leucine-rich diet: L – pregnant leucine, WL – tumour-bearing, and PL – pair-fed, which received the same amount of food as ingested by the WL group. The gastrocnemius muscle of WL rats showed increased incorporation of leucine in protein compared to W rats; the leucine-rich diet also prevented the decrease in plasma insulin normally seen in W. The expression of translation initiation factors increased when tumour-bearing rats fed leucine-rich diet, with increase of ~35% for eIF2α and eIF5, ~17% for eIF4E and 20% for eIF4G; the expression of protein kinase S6K1 and protein kinase C was also highly enhanced. The results suggest that a leucine-rich diet increased the protein synthesis in skeletal muscle in tumour-bearing rats possibly through the activation of eIF factors and/or the S6kinase pathway

  16. Cost-Utility of Group Acceptance and Commitment Therapy for Fibromyalgia Versus Recommended Drugs: An Economic Analysis Alongside a 6-Month Randomized Controlled Trial Conducted in Spain (EFFIGACT Study).

    Science.gov (United States)

    Luciano, Juan V; D'Amico, Francesco; Feliu-Soler, Albert; McCracken, Lance M; Aguado, Jaume; Peñarrubia-María, María T; Knapp, Martin; Serrano-Blanco, Antoni; García-Campayo, Javier

    2017-07-01

    The aim of this study was to analyze the cost utility of a group-based form of acceptance and commitment therapy (GACT) in patients with fibromyalgia (FM) compared with patients receiving recommended pharmacological treatment (RPT) or on a waiting list (WL). The data were derived from a previously published study, a randomized controlled trial that focused on clinical outcomes. Health economic outcomes included health-related quality of life and health care use at baseline and at 6-month follow-up using the EuroQoL and the Client Service Receipt Inventory, respectively. Analyses included quality-adjusted life years, direct and indirect cost differences, and incremental cost effectiveness ratios. A total of 156 FM patients were randomized (51 GACT, 52 RPT, 53 WL). GACT was related to significantly less direct costs over the 6-month study period compared with both control arms (GACT €824.2 ± 1,062.7 vs RPT €1,730.7 ± 1,656.8 vs WL €2,462.7 ± 2,822.0). Lower direct costs for GACT compared with RPT were due to lower costs from primary care visits and FM-related medications. The incremental cost effectiveness ratios were dominant in the completers' analysis and remained robust in the sensitivity analyses. In conclusion, acceptance and commitment therapy appears to be a cost-effective treatment compared with RPT in patients with FM. Decision-makers have to prioritize their budget on the treatment option that is the most cost effective for the management of a specific patient group. From government as well as health care perspectives, this study shows that a GACT is more cost effective than pharmacological treatment in management of FM. Copyright © 2017 American Pain Society. Published by Elsevier Inc. All rights reserved.

  17. Leucine-rich diet alters the eukaryotic translation initiation factors expression in skeletal muscle of tumour-bearing rats

    Energy Technology Data Exchange (ETDEWEB)

    Ventrucci, Gislaine [Laboratório de Nutrição e Câncer, Departamento de Fisiologia e Biofísica, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, 13083-970, São Paulo (Brazil); Mello, Maria Alice R [Departamento de Fisiologia e Biofísica, Instituto Biociências, Universidade Estadual de São Paulo, UNESP, Rio Claro, 13506-900, São Paulo (Brazil); Gomes-Marcondes, Maria Cristina C [Laboratório de Nutrição e Câncer, Departamento de Fisiologia e Biofísica, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, 13083-970, São Paulo (Brazil)

    2007-03-06

    Cancer-cachexia induces a variety of metabolic disorders on protein turnorver, decreasing protein synthesis and increasing protein degradation. Controversly, insulin, other hormones, and branched-chain amino acids, especially leucine, stimulate protein synthesis and modulate the activity of translation initiation factors involved in protein synthesis. Since the tumour effects are more pronounced when associated with pregnancy, ehancing muscle-wasting proteolysis, in this study, the influence of a leucine-rich diet on the protein synthesis caused by cancer were investigated. Pregnant rats with or without Walker 256 tumour were distributed into six groups. During 20 days of experiment, three groups were fed with a control diet: C – pregnant control, W – tumour-bearing, and P – pair-fed, which received the same amount of food as ingested by the W group; three other groups of pregnant rats were fed a leucine-rich diet: L – pregnant leucine, WL – tumour-bearing, and PL – pair-fed, which received the same amount of food as ingested by the WL group. The gastrocnemius muscle of WL rats showed increased incorporation of leucine in protein compared to W rats; the leucine-rich diet also prevented the decrease in plasma insulin normally seen in W. The expression of translation initiation factors increased when tumour-bearing rats fed leucine-rich diet, with increase of ~35% for eIF2α and eIF5, ~17% for eIF4E and 20% for eIF4G; the expression of protein kinase S6K1 and protein kinase C was also highly enhanced. The results suggest that a leucine-rich diet increased the protein synthesis in skeletal muscle in tumour-bearing rats possibly through the activation of eIF factors and/or the S6kinase pathway.

  18. Analysis of a Failed Eclipse Plasma Ejection Using EUV Observations

    Science.gov (United States)

    Tavabi, E.; Koutchmy, S.; Bazin, C.

    2018-03-01

    The photometry of eclipse white-light (W-L) images showing a moving blob is interpreted for the first time together with observations from space with the PRoject for On Board Autonomy (PROBA-2) mission (ESA). An off-limb event seen with great details in W-L was analyzed with the SWAP imager ( Sun Watcher using Active pixel system detector and image Processing) working in the EUV near 174 Å. It is an elongated plasma blob structure of 25 Mm diameter moving above the east limb with coronal loops under. Summed and co-aligned SWAP images are evaluated using a 20-h sequence, in addition to the 11 July, 2010 eclipse W-L images taken from several sites. The Atmospheric Imaging Assembly (AIA) instrument on board the Solar Dynamics Observatory (SDO) recorded the event suggesting a magnetic reconnection near a high neutral point; accordingly, we also call it a magnetic plasmoid. The measured proper motion of the blob shows a velocity up to 12 km s^{-1}. Electron densities of the isolated condensation (cloud or blob or plasmoid) are photometrically evaluated. The typical value is 108 cm^{-3} at r=1.7 R_{⊙}, superposed on a background corona of 107 cm^{-3} density. The mass of the cloud near its maximum brightness is found to be 1.6×10^{13} g, which is typically 0.6×10^{-4} of the overall mass of the corona. From the extrapolated magnetic field the cloud evolves inside a rather broad open region but decelerates, after reaching its maximum brightness. The influence of such small events for supplying material to the ubiquitous slow wind is noticed. A precise evaluation of the EUV photometric data, after accurately removing the stray light, suggests an interpretation of the weak 174 Å radiation of the cloud as due to resonance scattering in the Fe IX/X lines.

  19. Effects of leucine supplemented diet on intestinal absorption in tumor bearing pregnant rats

    Directory of Open Access Journals (Sweden)

    de Mello Maria

    2002-04-01

    Full Text Available Abstract Background It is known that amino acid oxidation is increased in tumor-bearing rat muscles and that leucine is an important ketogenic amino acid that provides energy to the skeletal muscle. Methods To evaluate the effects of a leucine supplemented diet on the intestinal absorption alterations produced by Walker 256, growing pregnant rats were distributed into six groups. Three pregnant groups received a normal protein diet (18% protein: pregnant (N, tumor-bearing (WN, pair-fed rats (Np. Three other pregnant groups were fed a diet supplemented with 3% leucine (15% protein plus 3% leucine: leucine (L, tumor-bearing (WL and pair-fed with leucine (Lp. Non pregnant rats (C, which received a normal protein diet, were used as a control group. After 20 days, the animals were submitted to intestinal perfusion to measure leucine, methionine and glucose absorption. Results Tumor-bearing pregnant rats showed impairment in food intake, body weight gain and muscle protein content, which were less accentuated in WL than in WN rats. These metabolic changes led to reduction in both fetal and tumor development. Leucine absorption slightly increased in WN group. In spite of having a significant decrease in leucine and methionine absorption compared to L, the WL group has shown a higher absorption rate of methionine than WN group, probably due to the ingestion of the leucine supplemented diet inducing this amino acid uptake. Glucose absorption was reduced in both tumor-bearing groups. Conclusions Leucine supplementation during pregnancy in tumor-bearing rats promoted high leucine absorption, increasing the availability of the amino acid for neoplasic cells and, mainly, for fetus and host utilization. This may have contributed to the better preservation of body weight gain, food intake and muscle protein observed in the supplemented rats in relation to the non-supplemented ones.

  20. Effects of leucine supplemented diet on intestinal absorption in tumor bearing pregnant rats

    International Nuclear Information System (INIS)

    Ventrucci, Gislaine; Mello, Maria Alice Roston de; Gomes-Marcondes, Maria Cristina Cintra

    2002-01-01

    It is known that amino acid oxidation is increased in tumor-bearing rat muscles and that leucine is an important ketogenic amino acid that provides energy to the skeletal muscle. To evaluate the effects of a leucine supplemented diet on the intestinal absorption alterations produced by Walker 256, growing pregnant rats were distributed into six groups. Three pregnant groups received a normal protein diet (18% protein): pregnant (N), tumor-bearing (WN), pair-fed rats (Np). Three other pregnant groups were fed a diet supplemented with 3% leucine (15% protein plus 3% leucine): leucine (L), tumor-bearing (WL) and pair-fed with leucine (Lp). Non pregnant rats (C), which received a normal protein diet, were used as a control group. After 20 days, the animals were submitted to intestinal perfusion to measure leucine, methionine and glucose absorption. Tumor-bearing pregnant rats showed impairment in food intake, body weight gain and muscle protein content, which were less accentuated in WL than in WN rats. These metabolic changes led to reduction in both fetal and tumor development. Leucine absorption slightly increased in WN group. In spite of having a significant decrease in leucine and methionine absorption compared to L, the WL group has shown a higher absorption rate of methionine than WN group, probably due to the ingestion of the leucine supplemented diet inducing this amino acid uptake. Glucose absorption was reduced in both tumor-bearing groups. Leucine supplementation during pregnancy in tumor-bearing rats promoted high leucine absorption, increasing the availability of the amino acid for neoplasic cells and, mainly, for fetus and host utilization. This may have contributed to the better preservation of body weight gain, food intake and muscle protein observed in the supplemented rats in relation to the non-supplemented ones