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Sample records for med almen praksis

  1. Kvalitet i almen praksis?

    DEFF Research Database (Denmark)

    Lippert, Maria Laura; Dyhr, Lise

    2015-01-01

    Artiklen beskriver en undersøgelse, der afdækkede, hvad der kan ske med læge-patient-samtalen, når der i kvalitetssikringsøjemed popper små skærmbilleder op med spørgsmål på lægens PC, der præsenterer faste standarder for indhold og forløb. Konsultationer blandt læger, som anvendte og udfyldte...

  2. Computerbrug i almen praksis

    DEFF Research Database (Denmark)

    Rosenstand, Jeppe; Waldorff, Frans Boch

    2008-01-01

    computer use to be extensive. 28% of patients reported their GP's computer use as extensive. These patients more often reported discomfort with their GP's computer use (OR 1.09), or stated that they did not get help with the problem they most wanted solved (OR 0.83), compared with patients who perceived...... their GP's computer use as less extensive. Men (OR 2.21) and patients over 55 years of age (OR 2.45) were also overrepresented in this group. CONCLUSION: Overall, patients were satisfied with their consultations. Patients generally perceived computer use as more extensive than doctors did. Where patients...

  3. Lærerens dilemma - mellem ideal og praksis: en virksomhedsteoretisk analyse af progressiv undervisning med it

    DEFF Research Database (Denmark)

    Lorentzen, Rasmus Fink

    Denne ph.d.-afhandling bidrager til det fagdidaktiske forskningsfelt inden for læreruddannelsen med viden om dansklæreres didaktiske praksis med it-understøttet progressiv undervisning i udskolingen. Afhandlingen leverer et svar på spørgsmålet om, hvordan progressiv undervisning med it i dansk ka...

  4. Almen praksis kan fremme lige adgang til sundhed for patienter med etnisk minoritetsbaggrund

    DEFF Research Database (Denmark)

    Bach Nikolajsen, Maria; Kallestrup, Per

    2018-01-01

    In 2014, Institute for Human Rights published the report "Equal access to healthcare - an analysis of general practitioners' meeting with patients from ethnic minorities". General practice may contribute to equal access to healthcare for this group of patients. This is, however, a challenge...

  5. Præsentation af symptomer i almen praksis hos patienter med cancer

    DEFF Research Database (Denmark)

    Nielsen, Tine Nørgaard; Hansen, Rikke Pilegaard; Vedsted, Peter

    2010-01-01

    and prostate cancer presented diagnosis-specific symptoms (change in bowel habits, cough and bladder dysfunction) as well as more non-specific symptoms (pain, weight loss and fatigue). The GPs interpreted the symptoms as alarm symptoms in 49%, as general symptoms in 24% and as non-cancer specific symptoms...

  6. Hvor kommer meninger fra? - en analyse af diskursiv praksis i forbindelse med bachelorvejledning og -skrivning

    DEFF Research Database (Denmark)

    Møller, Hanne

    2004-01-01

    Læreruddannelsen er placeret i uddannelseshierarkiet som en både professions og akademisk orienteret uddannelse, hvis forvaltere er placeret uden direkte forbindelse med hverken skolepraksis eller akademisk praksis. Den overordnede diskursorden er i læreruddannelsen reguleret ud fra en orienterin...... artiklen på "at mene" i læreruddannelsens diskursive praksis, og der identificeres en problemstilling som drejer sig om hvordan en lærerstuderende / kommende lærers position skal forstås som etableret af de ord den studerende producerer i BA-opgaven....

  7. Professionel praksis i botilbud for mennesker med udviklingshæmning

    DEFF Research Database (Denmark)

    Engen, Mie

    I dag varetager man i Danmark hovedsageligt omsorgen for mennesker med udviklingshæmning, der har behov for hjælp og støtte på døgnbasis, i § 107/108 boformer oprettet efter Lov om Social Service og Almenboliglovens § 105. Formålet med den professionelle praksis i boformerne er at varetage disse ...

  8. Varierende benzodiazepinordinationer i almen praksis

    DEFF Research Database (Denmark)

    Bjerrum, L; Christensen, P B; Larsen, P H

    1994-01-01

    The aim of this study was to describe differences in patterns of benzodiazepine prescription in Svendborg. All benzodiazepine prescriptions filled by the two pharmacies in Svendborg between February and 31 March 1990 were registered. During the period, 3364 prescriptions were issued to 2262 persons...... and the composition of the practice population we found that practices with a high prescription level had more women and elderly people enrolled than had the practices with a low prescription level. After standardization for age and sex the difference was reduced from 3.8 to 2.8, but practices with many elderly...

  9. Lægers erfaringer med systematiske gennemgange af patientforløb som læringsmetode i almen praksis

    DEFF Research Database (Denmark)

    Andersen, Rikke Sand; Søndergaard, Jens; Hansen, Rikke Pilegaard

    2009-01-01

    The study shows that GPs perceive systematic reviews of patient cases as potential learning vehicles. This is in line with adult learning theories, which argue that professional capability is best enhanced by situating learning in real-life contexts. This paper argues that we should think pragmat...

  10. Lægers erfaringer med systematiske gennemgange af patientforløb som læringsmetode i almen praksis

    DEFF Research Database (Denmark)

    Andersen, Rikke Sand; Søndergaard, Jens; Hansen, Rikke Pilegaard

    2009-01-01

    The study shows that GPs perceive systematic reviews of patient cases as potential learning vehicles. This is in line with adult learning theories, which argue that professional capability is best enhanced by situating learning in real-life contexts. This paper argues that we should think pragmat...... pragmatically when developing learning methods, and strengthen future efforts to develop methods that ensure reliable learning based on reviews of patient cases. Udgivelsesdato: 2009-Jan-19...

  11. Refleksiv praksis

    DEFF Research Database (Denmark)

    forskningspraksis. Forfattergruppens intention med denne antologi har været ved at fremlægge erfaringer fra egen forskning at kunne bidrage til inspiration, erfaringsudveksling og debat med såvel studerende som forskerkolleger om, hvordan forskning kan gribes an i praksis og om de indsigter og forståelser og...

  12. Markant stigning i antibiotikaforbruget i almen praksis

    DEFF Research Database (Denmark)

    Jensen, Ulrich Stab; Bjerrum, Lars

    2011-01-01

    The antimicrobial consumption in primary health care has increased notably during the latest decade. The increase has predominantly been among broad-spectrum antimicrobial agents. Denmark is no longer among the European countries with the lowest consumption. The reasons for these changes...... are not fully explained, but increased dosage for each treated patient and more patients treated have played an important role. To some extent, the consumption meets with relevant quality indicators for antibiotic prescribing, but the use of resistance inducing antibiotics needs to be limited according...

  13. Audit om rationel billeddiagnostik i almen praksis

    DEFF Research Database (Denmark)

    Andersen, Merethe Kirstine Kousgaard; Torfing, Trine; Ulrichsen, Walther

    2016-01-01

    Background and aim Diagnostic imaging is the second most used paraclinical examination in Denmark and 15% of all referrals from general practice concerns radiology. The fast development in diagnostic imaging constitutes a challenge for general practitioners’ when determining the right type of rad...

  14. Skal alkoholmisbrug overhovedet behandles i almen praksis

    DEFF Research Database (Denmark)

    Barfod, Sverre Malm

    1995-01-01

    Som en del af en international undersøgelse gennemførtes telefon-interviews ud fra et semi-struktureret spørgeskema af 12 tilfældigt udvalgte praktiserende læger samt personlige interviews af seks nøglepersoner i sundhedsvæsenet. Alle de udspurgte praktiserende læger var interesserede i at udføre...

  15. Patientkarakteristika og honoreringsmodeller for almen praksis

    DEFF Research Database (Denmark)

    Rose Olsen, Kim; Kristensen, Troels; Thomsen, Janus Laust

    2014-01-01

    ¬ordning, som bygger på en blanding af ”fee for service” og ”per capita”. Forfatterne diskuterer sammen¬hænge mellem helbred, socioøkonomi og afregningsmodeller. Meget taler for, at basishonoraret fremover bør differentieres efter patientens helbredstilstand og praksispopulationens socioøkonomiske...

  16. God IKT-praksis

    DEFF Research Database (Denmark)

    Wentzer, Helle

    Afhandlingen afdækker tværvidenskabelige problemstillinger for informatik fra et humanistisk perspektiv. 'God IKT-praksis' bidrager med udgangspunkt i sundhedssektoren med tre begreber til konstruktive design- og læreprocesser ved implementering og evaluering af IKT. Begreberne er: ‘E-tekstens po......Afhandlingen afdækker tværvidenskabelige problemstillinger for informatik fra et humanistisk perspektiv. 'God IKT-praksis' bidrager med udgangspunkt i sundhedssektoren med tre begreber til konstruktive design- og læreprocesser ved implementering og evaluering af IKT. Begreberne er: ‘E...

  17. Loyalitet i praksis

    DEFF Research Database (Denmark)

    Breddam, Mads Dupont

    Loyalitet i praksis – en etnologisk kulturanalyse af fænomenet den loyale forbruger , er en kvalitativ kulturanalyse af, hvordan loyalitet skabes i forbindelse med den danske detailhandels - og andelsorganisation Coop og Coops loyalitetsprogram CoopPlus. Undersøgelserne bygger på et empirisk...... undersøger , hvordan loyalitet gøres i praksis, ved at indkredse det analytiske og multiple fænomen den loyale forbruger . Tilgangen er, at loyalitet praktiseres, nå r medarbejdernes, medlemmernes og medejernes versioner af den loyale forbruger relateres til hinanden. Med andre ord fokuserer forfatteren på...

  18. Almen og praksisnær kompetenceudvikling for voksne

    DEFF Research Database (Denmark)

    Hviid, Marianne Kemeny; Keller, Hanne Dauer; Rasmussen, Annette

    Rapporten sammenfatter og diskuterer erfaringer og resultater fra forskningsdelen i projektet KOM-UD (Kompetenceudvikling i udkantsområder). Rapportens kapiteler behandler forskellige aspekter af arbejdet med praksisnær (og oftest virksomhedsrettet) almen voksenundervisning med brug af resultater...

  19. Når fagdidaktik må suppleres med en didaktik for fagligt samspil - om skriftlighed i Almen Studieforberedelse i stx

    DEFF Research Database (Denmark)

    Hobel, Peter

    2009-01-01

    kompetencer bedst kan udvikles i udfoldede rapporter eller i synopser, og hvilke funktionelle komponenter der skal indgå i disse for at de kan fungere som samspilsgenrer. 104 Jeg vil i mit oplæg præsentere mit bud på, hvordan man med udgangspunkt i Biggs og Collis’ SOLO-taxonomi kan udarbejde en typologi...

  20. Stordriftsfordele og optimal størrelse i almen praksis

    DEFF Research Database (Denmark)

    Kristensen, Troels

    2009-01-01

    , om der er uudnyttede økonomiske stordriftsfordele knyttet til den nuværende organisering af almenpraksis. Endvidere er det formålet at estimere en økonomisk "optimal" praksisstørrelse. Data: Der anvendes tværsnitsdata fra en stikprøve på 327 solo- og kompagniskabspraksis indeholdende administrative...

  1. Antibiotika i almen praksis. En fælles beslutning?

    DEFF Research Database (Denmark)

    Lindell, Johanna

    2015-01-01

    , as well as being more cost-efficient (SUM 2014,2). SDM has been shown helpful in the primary sector in lowering the use of antibiotics (Legare et al 2012), where growing resistance due to antibiotic overuse is a public health problem, with primary care responsible for 90% of the prescriptions in Denmark....... Using Conversation Analysis on a dataset of 13 cases this study investigates how treatment decisions for antibiotics are made in primary care and whether the interaction follows the ideal of SDM. It finds that most treatment recommendations are presented as decisions already made, not encouraging...

  2. Perspektiver for inspektorbesøg i almen praksis

    DEFF Research Database (Denmark)

    Kjaer, Niels Kristian

    2008-01-01

    of the Danish Association for Family Medicine. RESULTS: Educational appraisal in Danish teaching practices is assumed to have a positive impact on training. One 3-hours visit very 4th year is suggested, with the possibility for early revisits as needed. Two inspectors per visit and a primary focus on pedagogic......INTRODUCTION: General practice has always provided teaching and training in some form or another, and recent years have seen a discussion on an appraisal system based on visits to practices. The educational dimension of general practice has been described in several publications. Training...

  3. Screeningstest for depression i almen praksis. COOP/WONCA-kort

    DEFF Research Database (Denmark)

    Pedersen, J K; Damsbo, N; Kragstrup, J

    1999-01-01

    Depressed patients in general practice may be difficult to identify. Questionnaires may be used for screening but some of the existing instruments are difficult to use and have only to a limited degree been introduced in general practice. In this study 798 patients' answers to the COOP/WONCA chart...... "Feelings" were compared to GPs' diagnosis according to ICD-10 criteria for depressive single episode (F32). At cut-off2/3 (slight/moderate problems) the chart had a sensitivity of 89% (76-100%) and specificity of 75% (72-78%). The predictive value of a positive test was not higher than 33% for any cut......-off point and the predictive value of a negative test never less than 98%. A two-phased diagnostic strategy with the COOP/WONCA chart as step one is suggested as a possible and relatively simple way to optimize recognition of depressive patients in general practice....

  4. Farmakologisk behandling af mild ukompliceret hypertension i almen praksis

    DEFF Research Database (Denmark)

    Paulsen, Maja Skov; Christensen, Bo; Søndergaard, Jens

    2013-01-01

    pressure 90-99 mmHg; no diabetes or cardiovascular disease) did not reduce mortality or morbidity. The evidence for pharmacotherapy in patients having mild/uncomplicated hypertension is weak. However, current Danish guidelines have taken this into consideration in their recommendations of pharmacotherapy......Hypertension is an important risk factor for cardiovascular disease. In Denmark, patients with hypertension are primarily managed in primary care. A recent Cochrane review concluded that pharmacotherapy of patients with mild hypertension (systolic blood pressure 140-159 mmHg; diastolic blood...... to patients with mild/uncomplicated hypertension....

  5. Abdominal fedme og fedmerelaterede sygdomme hos patienter i almen praksis

    DEFF Research Database (Denmark)

    Haugan, Ketil; Rost, Dan; Knudsen, Nils

    2010-01-01

    Abdominal obesity is associated with type 2 diabetes, cardiovascular disease, dyslipidemia and hypertension. The prevalence of abdominal obesity and its relationship with these comorbidities have not previously been examined in Danish primary care patients.......Abdominal obesity is associated with type 2 diabetes, cardiovascular disease, dyslipidemia and hypertension. The prevalence of abdominal obesity and its relationship with these comorbidities have not previously been examined in Danish primary care patients....

  6. Integreret rapportering i praksis

    DEFF Research Database (Denmark)

    Pontoppidan, Caroline Aggestam; Sonnerfeldt, Amanda

    2017-01-01

    Formålet med denne artikel er at bidrage til en dybere forståelse af fænomenet integreret rapporte-ring () og, hvordan IIRC’s begrebsramme afspejles i praksis i virksomheder og af interessen-ter. Artiklen tager udgangspunkt i nyere empiriske forskningsprojekter, som bringer viden omkring......; 1) brugeres (stakeholders) informationsbehov, herunder anvendelsen og nytteværdien af og 2) praktiske udfordringer samt ’best practice’ tendenser inden for (ACCA, 2016; ACCA 2017; AcE, 2017; IFAC 2017)....

  7. Sprogbrug i praksis

    DEFF Research Database (Denmark)

    Axel, Erik

    2006-01-01

    Artiklen er et argument for at se på sprogbrug i stedet for sprog. Vi bruger sproget til at meddele os. Derfor må vi i vor forståelse af sprogbrug indbefatte brugere, sprogbrug og betydning. Der tages udgangspunkt i betydninger som et aspekt af praksis, og argumenteres for, at sproget ikke har be......, Potter og Wetherells. Endelig introduceres Roy Harris integrative lingvistik, der argumenterer for, at sprogbrugen må forstås som en samlet kommunikationssituation. Med udgangspunkt i Harris tilgang skitseres en praksisbaseret forståelse af sprog som redskab.  ...

  8. Machinima som kreativ praksis

    DEFF Research Database (Denmark)

    Frølunde, Lisbeth

    2014-01-01

    Video: Machinima som Kreativ Praksis. Videoen fortæller om de overordnede temaer i et forskningsprojekt der undersøgte nye former for online multimedie- og filmproduktion og fællesskaber med fokus på 'machinima' animation. Studiet af machinima var en del af et større dansk projekt og et nordisk f...... forskningprojekt om virtuelle verdener og teknologiudvikling, 2010-13. Videoen er præsenteret på Audiovisual Thinking nr. 7 under temaet: Den kreative økonomi....

  9. Specialeskrivining i samarbejde med praksis

    DEFF Research Database (Denmark)

    Jensen, Christine Damsbo

    2010-01-01

    at the Centre for Psychiatric Research, Risskov. The positive aspects were gaining experience in project work and streng-thening academic knowledge and professional networks by cooperation with nurses in practice, librarians and management. The writing process was demanding, and when individuals choose to write...

  10. Læring som improviseret udvikling af praksis

    DEFF Research Database (Denmark)

    Brinck, Lars

    2010-01-01

    Med afsæt i forfatterens fænomenografiske studie af amerikanske musikeres oplevelse af det at jamme diskuterer artiklen, hvorvidt jam-bandets spontant improviserende praksis kan give ny forståelse af rytmiske musikeres læring som et overordnet socialt fænomen. Ved at betragte jam-bandets praksis i...

  11. Supply Chain Management som interaktionel praksis

    DEFF Research Database (Denmark)

    Smith, Leo Feddersen; Lund, Anders

    2016-01-01

    I dette bidrag undersøger vi Supply Chain Management som en interaktionel praksis forankret i kommunikation. Med udgangspunkt i e-mail korrespondancer undersøger vi, hvordan køber-leverandør forholdet kommunikativt konstitueres mellem to danske SMVer og deres kinesiske leverandører. Det...

  12. Anmeldelse af Søren P. Krejler & Caroline Pontoppidan: Due diligence i praksis - med fokus på finansielle og juridiske forhold

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2012-01-01

    Artiklen anmelder det nævnte værk med særlig fokus på 1) forhold, der efterprøves ved due diligence, 2) afrapportering, 3) due diligence ved cross-border virksomhedskøb og 4) undersøgelsens sammenhæng med prisen på virksomheden.......Artiklen anmelder det nævnte værk med særlig fokus på 1) forhold, der efterprøves ved due diligence, 2) afrapportering, 3) due diligence ved cross-border virksomhedskøb og 4) undersøgelsens sammenhæng med prisen på virksomheden....

  13. Markedskommunikation i praksis

    DEFF Research Database (Denmark)

    Markedskommunikation handler om al kommunikation mellem aktørerne på et marked. Derfor er der ofte tale om vidtforgrenede processer, hvor budskaber bliver skabt i samarbejdet mellem aktører og sjældent kan styres af én afsender alene. Markedskommunikation i praksis tager udgangspunkt i denne dyna...

  14. A new questionnaire to identify bodily distress in primary care

    DEFF Research Database (Denmark)

    Budtz-Lilly, Anna; Fink, Per; Ørnbøl, Eva

    2015-01-01

    Mange patienter henvender sig i almen praksis med legemlige symptomer, som ikke passer med traditionelt definerede sygdomme (også kaldet medicinsk uforklarede eller funktionelle symptomer). På baggrund af forskning i almen praksis er der nu udviklet kriterier for en ny diagnose for patienter med ...

  15. Socialkonstruktionisme i praksis med operativ effekt

    DEFF Research Database (Denmark)

    Barfod, Jakob Rømer

    2011-01-01

    on a variety of challenging missions. Much attention is given to the preparation of teams performing these missions. The teams consist of leaders and personnel from very different organizational cultures and backgrounds who must work together under great pressure: If necessary, they must take the lives......Leadership with an operational effect The Danish Defense is undergoing radical changes. Traditionally, learning has sprung from a linear thinking with great emphasis on analysis of cause and effect. Today the Danish Defense needs to function as a deployable armed force conducting operations abroad...... successful program called ’leadership with operative effect’ based on social constructionist ideas. The Major has firsthand experience with the process from his Work in Afghanistan and has also worked with the program in his position as an instructor at the Royal Danish Army Officers’ Academy. The sum...

  16. Aktionsforskning skaber løsninger i praksis

    DEFF Research Database (Denmark)

    Lehmann, Sanne

    Aktionsforskning er et forskningsdesign, der anvendes til at generere nye løsninger i og viden om praksis i et tæt tværfagligt samspil mellem aktører fra viden institutioner, praksis og borgere. Aktionsforskningsmetoden er involverende, procesorienteret og dialogbaseret og dermed et alternativ til...... kvantitative og kvalitative metoder. Bogen giver en håndgribelig og pædagogisk indsigt i, hvordan aktionsforskning kan anvendes i relation til kortere projektforløb. Aktionsforskning introduceres som hele rammen om projektet med anvisninger til, hvordan du finder en god problemstilling, anvender teori, udfører...... bogen henvender sig til alle, der arbejder med praksisudvikling og problemorienterede projekter og har lyst til at prøve kræfter med aktionsforskning....

  17. Kvaliteten af resistensbestemmelser på urin i almen praksis er generelt god

    DEFF Research Database (Denmark)

    Søgaard, Per; Knudsen, Anette Flindt; Højbjerg, Tove

    2012-01-01

    a program for quality assessment. National quality requirements for susceptibility examinations have already been established. The clinical microbiological departments send simulated urines with bacteria of common UTI strains. The specimens are examined in general practice with routine methods. The results...... for a two-year period of susceptibility examinations are reported. Generally, the quality criteria were met....

  18. Computerbrug i almen praksis: patienters og lægers opfattelse

    DEFF Research Database (Denmark)

    Rosenstand, Jeppe; Waldorff, Frans Boch

    2008-01-01

    computer use to be extensive. 28% of patients reported their GP's computer use as extensive. These patients more often reported discomfort with their GP's computer use (OR 1.09), or stated that they did not get help with the problem they most wanted solved (OR 0.83), compared with patients who perceived...... their GP's computer use as less extensive. Men (OR 2.21) and patients over 55 years of age (OR 2.45) were also overrepresented in this group. CONCLUSION: Overall, patients were satisfied with their consultations. Patients generally perceived computer use as more extensive than doctors did. Where patients...

  19. Viden om og handlingsstrategier vedrørende håndeksem i almen praksis

    DEFF Research Database (Denmark)

    Hald, Marianne; Hansen, Dorte Gilså; Blands, Jette

    2007-01-01

    eczema was made by almost all respondents (98%). A more potent topical steroid was the most frequently prescribed medication, alternatively in combination with an antibiotic component. A subgroup (16%) wanted to prescribe a less potent topical steroid. Only 20% of the respondents wanted to refer...

  20. Kendskab til humant papillomvirus-relateret sygdom blandt kvinder i almen praksis

    DEFF Research Database (Denmark)

    Petersen, Lone Kjeld; Vaesel, Hanne; Brønsgaard, Poul Hede

    2009-01-01

    INTRODUCTION: Cervical cancer is caused by oncogenic human papilloma virus (HPV) serotypes. Types 16 and 18 are responsible for approximately 75% of all cases in Europe. Low-malignant serotypes like HPV 6 and 11 are the cause of approximately 90% of all cases of conyloma accuminata. Approximately...

  1. Helbredsscreening i almen praksis. Et kvalitativt studie om menneskers tanker og erfaringer

    OpenAIRE

    Bach Nielsen, Karen-Dorthe

    2013-01-01

    Despite the lack of evidence of the actual effects of general health screenings, it is still being discussed whether the screenings should be a public offer. There is a lack of scientific investigations concerning the influence of health screening on individual level over time, especially in relation to the screened people who have been cleared and the people who have declined the screening offer. Only few researchers have conducted detailed investigations regarding the individ...

  2. Benzodiazepinordinationer i almen praksis. En analyse of forbrugsmønstret for førstegangsbrugere

    DEFF Research Database (Denmark)

    Bjerrum, L; Andersen, U A

    1996-01-01

    ceased their use of benzodiazepines. Most of the patients ceased benzodiazepine medication on their own initiative. The doctor stopped the medication in 11% of the cases. The risk of a "repeat prescription syndrome" in continuation of the first prescription of a benzodiazepine seemed to be negligible...

  3. Kvaliteten af diagnostik og behandling af kronisk obstruktiv lungesygdom i almen praksis--sekundaerpublikation

    DEFF Research Database (Denmark)

    Lange, Peter; Rasmussen, Finn Vejlø; Borgeskov, Hanne

    2008-01-01

    We investigated whether the quality of management of COPD in general practice could be improved by the participation of general practitioners and their staff in a COPD-specific educational programme. One-hundred and fifty-four doctors participated in the study, and 2549 patient record forms were...... included in the first audit and 2394 in the second audit. We observed a significantly increased utilisation of spirometry from the first (52.7%) to the second audit (71.4%) (p quality of management. We conclude that participation in an educational...... programme can improve the quality of COPD care in general practice....

  4. Kvaliteten af resistensbestemmelser på urin i almen praksis er generelt god

    DEFF Research Database (Denmark)

    Søgaard, Per; Knudsen, Anette Flindt; Højbjerg, Tove

    2012-01-01

    In Denmark, many microbiological tests (microscopy, culture and susceptibility examinations) are done in general practice for the diagnosis of urinary tract infections (UTI). In 2006, the costs of susceptibility examinations were 28 million DKK. Some regional health authorities have established...... a program for quality assessment. National quality requirements for susceptibility examinations have already been established. The clinical microbiological departments send simulated urines with bacteria of common UTI strains. The specimens are examined in general practice with routine methods. The results...

  5. Ressourcer i teori og praksis

    DEFF Research Database (Denmark)

    Ressourceorientering som udgangspunkt for pædagogisk praksis. I bogen møder læseren en række metoder og konkrete tilgange, der på forskellig vis tager udgangspunkt i et ressourcesyn som princip og afsæt for praksis. Ud fra forskellige teoretiske tilgange giver bogen en række bud på, hvordan man s...

  6. Portfolio i Praksis

    DEFF Research Database (Denmark)

    Saltofte, Margit; Krill, Cecilia

    . Præsentationsfolien fokuserer på at præsentere et færdigt produkt eller resultat, mens arbejdsportfolien har fokus på proces, refleksion og læring. Til denne forskel knytter sig desuden helt naturligt en sondring imellem det delte og det private. Hvor præsentationsportfolio per definition er åben og har en modtager i...... sigte, er arbejdsportfolien i udgangspunktet lukket og privat. Det vil sige at man selv udvælger, hvad der skal ses af fx vejleder eller medstuderende – og hvad, der skal forblive privat. Portfolio i Praksis tilbyder desuden en række håndgribelige øvelser, der kan bruges som hjælp til at understøtte det...

  7. Når almenpædagogikken bliver den bedste forbyggelse af angst

    DEFF Research Database (Denmark)

    Hviid, Pernille; Esbjørn, Barbara Hoff; Villadsen, Jakob Waag

    2018-01-01

    Formålet med artiklen er at invitere til dialog mellem børneklinisk, almen udviklingspsykologisk og almen pædagogisk praksis med henblik på forebyggelse af angst hos børn. Artiklen forsøger at begrebsliggøre og videreudvikle kvaliteter ved den almene pædagogiske praksis i relation til børneklinis...

  8. Effect of a participant-driven health education programme in primary care for people with hyperglycaemia detected by screening

    DEFF Research Database (Denmark)

    Maindal, H T; Carlsen, A H; Lauritzen, T

    2014-01-01

    Dette 3-års opfølgningsstudie undersøger i et randomiseret design effekten af et 12-ugers deltager-involverende uddannelsesprogram i almen praksis for personer, som fik konstateret IGT, IFG eller type 2 diabetes ved screening i almen praksis i forbindelse med ADDITION-studiet. Uddannelsesprogramm...

  9. Afprøvning af et sundhedspædagogisk koncept målrettet voksne med psykisk sygdom i region Syddanmark – fokus på kompetenceudvikling af professionelle. Projekt ’Livsstilsguide i praksis (2015-2017)’

    DEFF Research Database (Denmark)

    Folmann Hempler, Nana; Saurbrey Pals, Regitze; Oest, Lone

    2017-01-01

    Særlig læring/særlig succes Behovsafdækningen i projektet peger på, at der er behov for at styrke professionelles kompetencer til at samarbejde med voksne med psykisk sygdom om sundhed. Nærværende projekt viser, at professionelle kan styrke samarbejdskompetencer vha. undervisning. Baggrund Voksne...

  10. Evalueringskultur i praksis

    DEFF Research Database (Denmark)

    Klausen, Martin Søland; Andersen-Mølgaard, Hanna

    Emne: undervisningsmetoder ; evaluering ; folkeskolen ; undervisning ; læring Præsentation og definition af begreber knyttet til arbejdet med evaluering og læring, samt en gennemgang af forskellige evalueringsmetoder og redskaber. Derudover diskuteres de didaktiske overvejelser man bør gøre sig i...

  11. Betonkrav og praksis

    DEFF Research Database (Denmark)

    Poulsen, E.

    Publikationen giver en historisk gennemgang af danske betonkrav, dansk projektering- og udførelsespraksis samt eksisterende viden om betons holdbarhed. Stoffet er belyst med eksempler fra skadesager, og det beskrives, hvordan holdbarhedskrav er blevet opfattet på forskellige tidsspunkter....

  12. Loyalitet i praksis:En etnologisk kulturanalyse af fænomenet den loyale forbruger

    OpenAIRE

    Breddam, Mads Dupont

    2015-01-01

    Loyalitet i praksis – en etnologisk kulturanalyse af fænomenet den loyale forbruger , er en kvalitativ kulturanalyse af, hvordan loyalitet skabes i forbindelse med den danske detailhandels - og andelsorganisation Coop og Coops loyalitetsprogram CoopPlus. Undersøgelserne bygger på et empirisk materiale , som hovedsageligt består af kvalitative interviews med en række medlemmer og medejere af Coop samt med medarbejdere i Coops hovedkvarter i Albertslund . Afhandlingen er en praksiografisk under...

  13. Dagslysberegninger i praksis

    DEFF Research Database (Denmark)

    Iversen, Anne; Roy, Nicolas; Hvass, Mette

    Formålet med rapporten er at opnå en bedre forståelse af, hvad en dagslysberegning viser, og hvordan de forskellige beregningsprogrammer beregner i forhold til hinanden. Erfaringer har vist, at beregningsresultaterne fra to beregningsprogrammer til dagslysberegning kan være meget forskellige i de...... simuleringsprogrammer er undersøgt og sammenlignet. Det drejer sig om: Radiance, Daysim, VELUX Daylight Visualizer, Dialux, Ecotect, Ecotect / Radiance, IESve, LightCalc, Relux Radiosity og Relux Raytracing....

  14. Rummelighed i praksis

    DEFF Research Database (Denmark)

    Holt, Helle; Mehlsen, Line

    ansættelser af personer i fleksjob – skal etableres på en måde, så det kommer både arbejdspladserne og de inkluderede til gode. Undersøgelsen er baseret på dybdegående interview i tre kommuner og på ni arbejdspladser. Der er udført interview med direktioner, HR-afdelinger, jobcentermedarbejdere......, tillidsrepræsentanter, lokale ledere, kommunalt ansatte samt personer, der har været i fx virksomhedspraktik, i et løntilskudsforløb, eller som er blevet ansat i et fleksjob på en kommunal arbejdsplads. Undersøgelsen er igangsat og finansieret af Kommunernes Landsforening og Forhandlingsfælleskabet....

  15. Discrepancy in HbA1c Measurements Performed at Different Local Laboratories and a Selected Central Reference Laboratory

    DEFF Research Database (Denmark)

    Jensen, O.N.; Olivarius, Niels de Fine; Petersen, P.H.

    1993-01-01

    De aktuelle meget store praktiske problemer med laboratoriernes forskellige normalområder for Hæmoglobin A1c er illustreret vha. resultater fra projektet Diabetesomsorg i almen praksis. Udgivelsesdato: 1994...

  16. Evidensbaseret praksis i videnskabsteoretisk belysning

    DEFF Research Database (Denmark)

    Hjørland, Birger

    2011-01-01

    alle led i dokumentations- og søgeprocesserne. Evidensbaseret praksis er imidlertid også en kontroversiel bevægelse, især i bløde områder som psykologi, sygepleje og biblioteks- dokumentations- og informationsfaget (BDI), men også inden for medicin selv. Hovedkritikken går dels på, at praktikere...... fratages deres autonomi og på, at forståelsen for grundlæggende årsagsmekanismer svækkes. Denne videnskabsteoretiske kritik er ikke blot relevant for praktiseringen af fx evidensbaseret medicin, men også for BDIs forhold til dokumentationsprocesser generelt. Artiklen præsenterer og undersøger disse...

  17. Tre års anxiolytikaforbrug i almen praksis. En retrospektiv opgørelse fra en to-mands-landpraksis

    DEFF Research Database (Denmark)

    Christensen, P B; Bjerrum, L; Glent-Madsen, L

    1992-01-01

    %) than did the short term users (12%). Long term users consulted the doctor twice as frequently and were admitted to psychiatric departments six times as frequently during the period. One fourth of the long term users received disability pensions and one fourth had now or had previous alcohol problems......In a rural general practice with two doctors and 3.671 patients and employing a practice data system (APEX), a retrospective review was undertaken of the anxiolytic drugs (ATC gr NO5B) prescribed. A total of 376 persons received 3,556 prescriptions for a total of 121,111 DDD (Defined Daily Doses......). Forty of these patients (approximately 10%) received half of the medicine involved and half of the patients received 5% of the medicine. 68% of the prescriptions were renewals without contact between doctor and patient. A total of 85 new users was observed and the number of new users/annum decreased...

  18. Betydning af indkaldelse og brugerbetaling for influenzavaccination blandt aeldre. Et randomiseret kontrolleret forsøg i almen praksis

    DEFF Research Database (Denmark)

    Nexøe, J; Kragstrup, J; Rønne, T

    1997-01-01

    Influenza epidemics are accompanied by considerable excess morbidity and mortality especially among the elderly and the chronically ill. In the influenza season 1995 a controlled, randomized trial was carried out to examine the impact of postal invitations and user fee on influenza vaccination...... invitations to influenza vaccination paying the usual fee ($40-$60 US). The last third served as a control group, being vaccinated on their own request and paying the usual fee. In the control group 25% (19-31%, 95% confidence interval) of the patients were vaccinated, compared to 49% (42-56%) in the group...... which received a postal reminder and paid the usual fee, and 72% (65-78%) in the group invited to be vaccinated free of charge. Udgivelsesdato: 1997-Jun-30...

  19. Nærvær i pædagogisk praksis

    DEFF Research Database (Denmark)

    Nærvær i pædagogisk praksis handler om, hvordan lærere og pædagoger kan arbejde med mindfulness i skole og daginstitution. Målet er at give inspiration til, hvordan man kan skabe et lærings- og udviklingsmiljø, som understøtter en praksis, hvor børn får erfaringer med at være til stede i sig selv......, ligesom de giver eksempler på nærværende kunst- og musikundervisning.   Den røde tråd er ønsket om at bistå barnet i at rumme sig selv og andre og en interesse for de muligheder, som øget nærvær kan give det enkelte barn og fællesskabet....

  20. Når systematiske reviews (mis)informerer pædagogisk praksis

    DEFF Research Database (Denmark)

    Engsig, Thomas Thyrring

    2015-01-01

    I løbet af de sidste ti år har vi, nationalt såvel som internationalt, været vidne til en betydelig vækst i produktionen af systematiske reviews inden for pædagogik og uddannelse. I forbindelse med omfattende reformer af dele af den pædagogiske praksis og professionsuddannelserne til pædagog og l...

  1. Skole-hjemsamarbejde i praksis

    DEFF Research Database (Denmark)

    Hansen, Lisbeth; Balvig-Phillips, Line

    i årene 2009 til 2013 til uddannelse og aflønning af skolehjemvejledere med særligt fokus på samarbejdet med nydanske forældre. For løbende at formidler skole-hjemvejledernes erfaringer udgiver Social- og Integrationsministeriet i 2011, 2012 og 2013 et inspirationshæfte med de bedste historier og...... for skolehjemvejledere og skole-hjemvejledernes elektroniske netværk på Google Groups....

  2. Etikk i praksis: Barn med samspillsvansker og medvirkning i barnehagen

    Directory of Open Access Journals (Sweden)

    Ingvild Åmot

    2012-11-01

    Full Text Available Title: Ethics in practice: Children who have difficulties interacting and their participation in day-care centres.Abstract: In recent years there has been a trend promoting "children’s right to participation". The point of departure for the article is qualitative data material collected from three day-care centres in Norway. The main objective has been to illuminate the choices the staff have and the dilemmas they face in their day-to-day practice when it comes to children who have interaction difficulties and their opportunities to participate. Findings: The practice is action-oriented. Actions, dilemmas and discretionary assessments are related to consequential- and deontological-ethics reasons.

  3. Erfaringer med dokumentation af musikterapeutisk praksis i kommunal demensomsorg

    DEFF Research Database (Denmark)

    Krøier, Julie Kolbe; Jefsen, Anders

    2016-01-01

    Denne artikel afdækker centrale erfaringer fra etableringen af faste musikterapitilbud i kommunerne Hillerød og Sønderborg. I begge kommuner er musikterapien blevet et fast tilbud på baggrund af en prøvepe- riode, og der er blevet skabt en systematisk dokumentationspraksis. Denne er blevet etable...

  4. Implementeringsforskning: vitenskap for forbedring av praksis

    Directory of Open Access Journals (Sweden)

    Signe Flottorp

    2013-11-01

    Full Text Available Medisinsk forskning har ført til store framskritt de siste tiårene. Det er investert mye mer ressurser på basalforskning og klinisk forskning enn på å utvikle og evaluere metoder for å sikre at pasientene får nytte av forskningen. Formålet med implementeringsforskning er å redusere gapet mellom forskning og praksis, ved å utvikle og evaluere tiltak som kan sikre at behandlingen som pasientene mottar er kunnskapsbasert, at den er omsorgsfull og av god kvalitet.I denne artikkelen gjør vi rede for hva implementering og implementeringsforskning er. Vi belyser historikken til denne unge vitenskapen, og illustrerer mangfoldet i de faglige tilnærmingene og begrepene som brukes om det å få forskning brukt i praksis. Det finnes en rekke teorier om endring av atferd, både på individnivå og på organisatorisk nivå. Teoriene er imidlertid i liten grad testet empirisk, særlig når det gjelder å endre atferd i helsetjenesten.Systematiske oversikter over metodisk gode studier er den beste kilden til informasjon om effekt av implementeringstiltak. The Cochrane Effective Practice and Organisation of Care Group (EPOC er en viktig kilde for slike oversikter. De systematiske oversiktene som er utarbeidet på dette feltet viser at passive dissemineringstiltak har begrenset effekt, mens mer aktive tiltak kan ha liten til moderat effekt. Det er ofte betydelig variasjon i effekt på tvers av studiene. Det er derfor viktig å få bedre kunnskap om hvilke faktorer som kan forklare slike forskjeller i effekt.Vi gir eksempler på norske implementeringsstudier, og refererer bidrag fra forskere ved Kunnskapssenteret. Implementeringsforskningen kan, hvis den lykkes, sikre pasientene bedre behandling.Flottorp S, Aakhus E. Implementation research: science for improving practice. Nor J Epidemiol 201 3; 23 (2: 187-196.ENGLISH SUMMARY Medical research has led to major advances in recent decades. More resources have been invested in basic and clinical research

  5. Forskningsbaseret viden kan bruges i praksis

    DEFF Research Database (Denmark)

    Braad, Mette; Bahnsen, Iben Bøgh; Axelsen, Hanne Clement

    2013-01-01

    Evidensbaseret praksis blev trænet i et samarbejde mellem sygeplejestuderende, kliniske vejledere og undervisere på sygeplejerskeuddannelsen i Aalborg. Resultatet af samarbejdet kommer nu præmature børn i CPAP-behandling til gode i form af systematisk soignering, aflastning og gel-behandling omkr......Evidensbaseret praksis blev trænet i et samarbejde mellem sygeplejestuderende, kliniske vejledere og undervisere på sygeplejerskeuddannelsen i Aalborg. Resultatet af samarbejdet kommer nu præmature børn i CPAP-behandling til gode i form af systematisk soignering, aflastning og gel...

  6. Adherence to COPD guidelines in general practice

    DEFF Research Database (Denmark)

    Ulrik, Charlotte Suppli; Sørensen, Tina Brandt; Højmark, Torben Brunse

    2012-01-01

    I forbindelse med et efteruddannelsesprogram for almen praksis inden for kronisk obstruktiv lungelidelse (KOL) fandt vi, at de praksis, der deltog i denne efteruddannelse i højere grad levede op til KOL-vejledningen, som denne er defineret ud fra DSAM’s vejledning. Det bliver ofte diskuteret i hv...

  7. Princip på praksis

    DEFF Research Database (Denmark)

    Hendricks, Vincent Fella

    2011-01-01

    Det engelske begreb ”affirmative action”, på dansk ”positiv særbehandling” optræder for første gang i den amerikanske eksekutivforordning nr. 10925 underskrevet af John F. Kennedy i 1961 som et forsøg på at komme diskrimination til livs. Generelt er formålet med positiv særbehandling at skabe lige...

  8. From Practice to Praksis - models in Danish coaching psychology

    DEFF Research Database (Denmark)

    Spaten, Ole Michael; Kyndesen, Anna Imer; Palmer, Stephen

    2012-01-01

    The article gives a brief outline of the broadness of coaching models and moves on to describe in detail the model PRAKSIS, which has been developed from the English language PRACTICE model. This model is considered to be a key tool in solution-focused coaching and therapy. Thus, PRAKSIS...

  9. Ikke alt, der hvæser, hos børn er astma

    DEFF Research Database (Denmark)

    Hermann, Christian

    2000-01-01

    Med udgangspunkt i projektet "Opsporing af astma i 5 års alderen i almen praksis" beskrives asthma i barnealderen som en folkesygdom, der fylder meget i praksis. Det vigtige i tidlig diagnosticering understreges, da man i dag har effektiv medicin og viden om forebyggelse, der om ikke kurerer...... sygdommen så forbedrer trivselen betydeligt. Sygdomsbilledet i almen praksis ligger i grænseområdet til banalt luftvejsbesvær, hvorved det adskiller sig betydeligt fra astma sygdomsbilledet, som det optræder i hospitalssektoren og er beskrevet i lærebøgerne, hvilket er baggrunden for ovennævnte projekt...

  10. Hvordan diagnosticerer man astma hos børn?

    DEFF Research Database (Denmark)

    Hermann, Christian

    1997-01-01

    Astma og astmatisk bronkit har ens symptomatologi og behandling og kan med vore dages effektive og bivirkningssvage medicin selv i de lettere grader behandles. Symptomerne kender vi i praksis fra op mod 1/3 af småbørnene, kunsten består i at stille behandlingsindikationen. Der opridses overvejende...... udfra kliniske kriterier enkle retningslinier, der nyder konsensus blandt danske almenmedicinere og pædiatere til hjælp i den daglige håndtering af sådanne symptomer i almen praksis. Til slut understreges, at opsporing af astma og astmatisk bronkitis naturligt hører hjemme i almen praksis, og...

  11. Ledelsesretten - hvad skal vi stille op med den?

    DEFF Research Database (Denmark)

    Pagh, Lone

    2016-01-01

    for ledelsesretten at træde ind som en kommunikerbar og legitim rammesætning i lederens praksis. Artiklen inddrager i sin analyse retssociologiske perspektiver i et moderne og postmoderne perspektiv og rundes af med en diskussion af de faldgruber, det kan indebære, når ledelsesrettens styringssprog skal omsættes til...

  12. Diagnoses of Patients with Severe Subjective Health Complaints in Scandinavia: A Cross Sectional Study

    DEFF Research Database (Denmark)

    Maeland, Silje; Werner, Erik L.; Rosendal, Marianne

    2012-01-01

    Patienter med symptomer, der ikke umiddelbart passer med en kendt medicinsk diagnose, er hyppige i almen praksis. Praktiserende læger blev i denne undersøgelse bedt om at sætte en diagnosekode på disse patienter, og der viste sig at være en meget stor variation i valget med op til 31 forskellige ...

  13. Læring i praksis. Tilrettelegging for å fremme refleksjonskompetanse og læringsutbytte hos studenter i praksis. Erfaringer fra en pilotstudie.

    Directory of Open Access Journals (Sweden)

    Kari Høium

    2009-02-01

    Full Text Available Studien belyser erfaringer med en tilpasset veiledningsmodell i gruppe, for å styrke profesjonell kompetanse hos vernepleiestudenter i praksis. Intervensjonen er gjennomført i forhold til 32 bachelorstudenter fra tre ulike kull. Den tar utgangspunkt i en obligatorisk veiledningsgruppe som foregår inne på høgskolen, midtveis i en av deres praksisperioder. Hovedmålsettingen var å se i hvilken grad veiledningsmodellen bidro til utbytte og læringseffekt i forhold til målsetting for praksisperioden. Et annet mål med studien har vært å skaffe erfaringer med hvordan refleksjon og kritisk tenkning kan læres gjennom praktisk student veiledning. Resultater fra undersøkelsen viste at den tilpassede veiledningsmodellen som her ble benyttet, bidro til å fremme refleksjonskompetanse og læringsutbytte hos studentene. Dette gir grunnlag for videre optimisme med tanke på å styrke vernepleiestudentenes læring og profesjonelle kompetanse. Betydningen forsterkes ved at refleksjonskompetanse fremheves som en sentral kvalitetsvariabel, både fra myndighetene og fra fagfeltet. En videre utfordring vil være å raffinere modellen ytterligere med tanke på utprøving og tilpasset implementering gjennom ulike praksisperioder i studiet.

  14. Symptom attributions in patients with colorectal cancer

    DEFF Research Database (Denmark)

    Jensen, Line Flytkjær; Hvidberg, Line; Pedersen, Anette Fischer

    2015-01-01

    Størstedelen af kolorektal cancere opdages gennem patienters symptomatiske henvendelse i almen praksis. Man ved dog ikke meget om, hvordan patienter selv oplever deres symptomer. Formålet med studiet var, at undersøge om symptom attributioner er associeret med hvilket symptom man oplevede før...

  15. Udvidelsen af relationsfeltets didaktik – med religionsundervisningen som eksempel

    DEFF Research Database (Denmark)

    Skovmand, Keld

    beskrive denne dobbeltbevægelse som en almen fagdidaktik (Nielsen 1998 [1994]) eller – med inspiration fra Klafki – en relationsfeltets didaktik (Nielsen 2012). Dobbeltblikket på didaktikken som et relationsfelt kan kvalificeres ved hjælp af de fire kriterier for indholdsvalg, som er udformet af Frede V...... specificere indhold (DuFour & Marzano 2011). Referencer DuFour, Richard & Marzano, Robert J. 2011: Leaders of learning. How district, school, and classroom leaders improve student achievement. Bloomington, IN: Solution Tree Press. Hattie, John 2009: Visible learning. A synthesis of over 800 meta...

  16. Randomiseret, kontrolleret undersøgelse af anvendelsen af CRP-hurtigtest som vejledning ved behandlingen af luftvejsinfektioner i almen praksis

    DEFF Research Database (Denmark)

    Diederichsen, H Z; Skamling, M; Diederichsen, Axel Cosmus Pyndt

    2001-01-01

    The aim was to assess whether the frequency of antibiotic prescriptions to patients with respiratory infections is reduced when general practitioners (GPs) use a CRP rapid test to support their clinical assessment, and to examine whether the use of the test would have any effect on the course...

  17. Pierre Bourdieu/ Praksis, uddannelse og symbolsk vold

    DEFF Research Database (Denmark)

    Wilken, Lisanne

    2012-01-01

    Artiklen giver en kort introduktion til nogle af Bourdieus væsentligste begreber og hans bidrag til en sociologi med afsæt i uddannelse......Artiklen giver en kort introduktion til nogle af Bourdieus væsentligste begreber og hans bidrag til en sociologi med afsæt i uddannelse...

  18. Forum for Almen Medicinske ph.d.-studerende

    DEFF Research Database (Denmark)

    Vedsted, Peter; Waldorff, Frans Boch; Eriksson, Tina

    Rapport fra første fællesmøde mellem nuværende og kommende almenmedicinske ph.d.-studerende. Rapporten anbefaler dannelse af et egentligt almenmedicinsk ph.d.-forum, der søges optaget i DSAM som en interessegruppe. Ph.d.-forum betragter sig som en ressource ved forskellige initiativer og ønsker...... blandt andet at arbejde for en værdig ansættelse af yngre forskere. Blandt de konkrete forslag, Ph.d.-forum har stillet, er almenmedicinske ph.d.-kurser og ph.d.-stipendium med henblik på udarbejdelse af protokol....

  19. At finde rundt i klinisk praksis og om de enkelte rums funktion og betydning

    DEFF Research Database (Denmark)

    Larsen, Kristian

    2013-01-01

    de rumlige omgivelser er relevant, fordi læring i praksis i højeste grad foregår i fysiske, arkitektoniske rammer med specifikke sociale spilleregler for, hvad man gør og ikke gør i et konferencerum, en sygestue eller i patientens eget hjem. Arkitektur er således materielt og kropsligt nærværende...... læremester, og rumlige omgivelser involverer også magtrelationer,som hvem der besidder hvilke lokaliteter og artefakter og hvem, der ikke gør det. Dette kapitel angår relationer mellem mennesker og fysiske omgivelser, og det er hensigten at gøre rede for både enkle og komplekse forhold. I den forbindelse vil...

  20. Resource allocation and health care needs in diabetes care in Danish GP clinics

    DEFF Research Database (Denmark)

    Kristensen, Troels; Rose Olsen, Kim; Sortsø, Camilla

    2013-01-01

    ydelsesbaseret honorering per type 2 diabetes mellitus (T2DM) patient, som kan forklares af patienternes co-morbiditetsbyrde og sygdomskarakteristika. Metode og data: Patientmorbiditets-karakteristika som f.eks. diagnostiske markører, co-morbiditets casemix justering og udgifter til ydelsesbaseret honorering per......Titel: Ressourceallokering og behov i diabetes behandlingen i dansk almen praksis Baggrund: I en række lande har myndighederne ændret systemet til allokering af ressourcer i almen praksis fra et demografisk baseret til et morbiditetsbaseret casemix system. I dansk almen praksis er der ikke indført...... et morbiditetsbaseret case mix justeringssystem. Det kan være relevant at undersøge, hvordan den danske ressourceallokering fungerer i forhold til morbiditet og sygdomskarakteristika hos patienter. Formål: Formålet med dette studie er at vurdere hvilken andel af variationen i udgifterne til...

  1. Kombinerede sol/varmepumpeanlæg i praksis

    DEFF Research Database (Denmark)

    Andersen, Elsa; Furbo, Simon

    2010-01-01

    I rapporten analyseres målinger fra kombinerede sol/varmepumpeanlæg i praksis. Anlæggene er installeret af Nordic Energy Group og målingerne er ligeledes foretaget af Nordic Energy Group. Analysen viser at energiforbruget og energiprisen kan reduceres betragteligt ved at installere et kombianlæg ...

  2. Skal det være slut med herreløse katte i Danmark?

    DEFF Research Database (Denmark)

    Sandøe, Peter

    2015-01-01

    En arbejdsgruppe med deltagelse af bl.a. Den Danske Dyrlægeforening og Dyrenes Beskyttelse foreslår at enhver, der fodrer en herreløs kat, skal vedkende sig ejerskab. Professor Peter Sandøe kritiserer arbejdsgruppens forslag, som han mener i praksis vil forværre forholdene for de herreløse katte....

  3. Miljøoptimering af afvaskning ved tryk med vandfortyndbar flexotrykfarve

    DEFF Research Database (Denmark)

    Larsen, Henrik Fred; Helweg, Christian; Pedersen, Anne Rathmann

    Rapporten beskriver praksis ved afvaskning af vandfortyndbare flexotrykfarver i emballageindustrien og anviser muligheder for indførelse af renere teknologi til reduktion af spildevandsbelastningen. Anbefalingerne omfatter a) udformning af farveværker med henblik på effektiv tømning af farve og e...

  4. Space Sharing i teori og praksis

    DEFF Research Database (Denmark)

    Brinkø, Rikke

    2016-01-01

    Dette er den anden artikel i FM Update, der præsenterer resultater fra Ph.d. studiet ”Sharing Space in the Knowledge City” fra DTU. Den første artikel med titlen ”Shared Space – mellem vision og realitet” (FM-Update, nr. 1, 2015) præsenterede en ny typologi for shared space, som delekoncept. Denne...... artikel er en fortsættelse, med fire dybdegående studier af eksempler på bygge- og renoveringsprojekter, som afspejler de fire typer at shared space, som beskrives i typologien. Formålet med denne artikel er dels at eksemplificere de fire typer af shared space, og dels at formidle erfaringer fra...

  5. Use of general practice before and after mild traumatic brain injury: a nationwide population-based cohort study in Denmark

    DEFF Research Database (Denmark)

    Galili, Stine Fjendbo; Bech, Bodil Hammer; Vestergaard, Claus Høstrup

    2017-01-01

    Milde hovedtraumer ses hyppigt i de danske akutafdelinger, og følgevirkningerne af milde hovedtraumer er stærkt omdiskuterede. Formålet med dette nationale studie var at beskrive brugen af almen praksis før og efter et mildt hovedtraume og bruge antallet af kontakter som en proxy variabel...

  6. Bereavement care in general practice

    DEFF Research Database (Denmark)

    Guldin, Mai-Britt; Vedsted, Peter; Jensen, Anders Bonde

    2013-01-01

    I dette studie testes effekten af en klinisk intervention over for håndtering af sorg i almen praksis. Interventionen handlede om, at tidlig identifikation af komplicerede sorgreaktioner via praktiserende læge kan være med til at sikre behandling til behandlingskrævende sorgreaktioner, der volder...

  7. Værdibasering som kommunal praksis

    DEFF Research Database (Denmark)

    Ostrowski, Kasper

    2009-01-01

    og tværkommunale forskelle foranlediget af kommunalreformen i Danmark. Begrebet ’værdibaseret ledelse’ gestaltes ofte med en både frustrerende lethed og på fascinerende vis som fænomen. Dette har ansporet min interesse for i denne afhandling at undersøge, hvorledes værdibaseret ledelse kan forstås...

  8. Skattemæsssig kvalifikation af trusts i praksis

    DEFF Research Database (Denmark)

    Feldthusen, Rasmus Kristian

    2013-01-01

    Artiklen har til formål at systematisere og redegøre for skattemyndighedernes fremgangsmåde og kvalifikation af trusts i dansk ret. Baggrunden herfor er, at antallet af trust-sager for såvel de administrative myndigheder som domstolene relativt set er vokset betydeligt siden årtusindeskiftet. Ud...... fra en gennemgang af doms- og administrativ praksis kan det konstateres, at kvalifikationen af trusts kan opdeles i fire hovedkategorier, som er væsentlige at have kendskab til, såfremt en skattesag indeholdende trust-elementer måtte være under opsejling. Endvidere inddrages skattestrafferetlig...... praksis på baggrund af en nyligt afsagt landsretsdom vedrørende en offshore trust....

  9. Håndbold er en praksis!

    DEFF Research Database (Denmark)

    Olsen, Poul Bitsch

    2008-01-01

    Dansk håndbold er en kæmpemæssig succeshistorie. Ser man snævert på den udvikling, elitedelen af sporten har gennemlevet de seneste 15 år, viser stort set alle tænkelige parametre fremgang. De internationale resultater for lands og klubhold er med få udfald blevet stadigt bedre, omsætningen i klu...

  10. Udsathed som dilemma i ungdomsklubbens praksis

    DEFF Research Database (Denmark)

    Tireli, Üzeyir

    2016-01-01

    Ungdomsklubber er i færd med at genfinde deres ståsted i en tid, hvor skolereformen på den ene side og digitalisering samt individualisering på den anden side presser ungdomsklubbens indholdsmæssige rammer og strukturer. Det gælder i høj grad også for de ungdomsklubber der ligger i socialt udsatt...

  11. Pædagogik som en filosofisk praksis

    DEFF Research Database (Denmark)

    Hansen, Finn Thorbjørn

    2006-01-01

    Artiklen (50 sider) indledes med nogle betragtninger over, hvad pædagogisk filosofi er og der gives en beskrivelse af dets tre dimensioner. Artiklen vægter særlig den tredie dimension - den maieutiske dimension - hvor det er den pædagogiske filosofi I den konkrete pædagogiske virksomhed, der unde......), mindre grupper (den sokratiske dialoggruppe) og på to-mands-hånd (den filosofiske vejledningspraksis). Artiklen ender i en perspektivering, hvor der spørges til muligheden af et "sokratisk citizenship" set i lyet af individualiseringen og multikulturaliseringen i uddannelsessystemet....

  12. Supervision af psykologkandidater i privat praksis

    DEFF Research Database (Denmark)

    Petersen, Birgitte

    et litteratur review over relevante temaer i supervisionslitteraturen samt overvejelser om læring i supervision. Afhandlingens empiriske resultater vil blive belyst og diskuteret med udgangspunkt i tilsvarende fænomener i supervisionslitteraturen. Resultaterne af undersøgelsen viser, at der er en...... række vigtige elementer ved supervision, der skal være opfyldt, hvis den skal opleves som udviklende og lærerig af praksiskandidaterne. Det er elementer som kontraktetablering, rådgivning og teoretisk refleksion, en tydelig teoretisk referenceramme samt støtte og anerkendelse fra supervisor. Det...

  13. Feltarbejde omkring en æstetisk praksis i børnehaven

    DEFF Research Database (Denmark)

    Lica, Anna

    2008-01-01

    Baggrunden for projektet Feltarbejde omkring æstetisk praksis i børnehaven er mit job som underviser i drama på et pædagogseminarium. I den forbindelse er jeg i faglige diskussioner løbet ind i en mur, når det gjaldt indkredsningen af begrebet æstetisk praksis. Dette pirrede til min nysgerrighed...

  14. Dybder og Overflader i styring, viden og praksis i det sociale og psykiatriske arbejde med sindslidende

    DEFF Research Database (Denmark)

    Ringø, Pia

    2013-01-01

    The thesis ”Depths and surfaces in management, knowledge and practice in social and psychiatric work” examines whether specific technological processes bring about specific tools of observation and particular methods and instruments for outlining, categorizing and diagnosing social and psychiatric...... problems in a network of concepts, technologies, institutions and practices - as well as the specific problem solving strategies established to intervene, alter and improve that which is considered problematic about the individual. The thesis challenge traditional paradigmatic boundaries of knowledge...

  15. Socioeconomic position and contact to general practice among persons with diabetes

    DEFF Research Database (Denmark)

    Dalsgaard, Else-Marie; Vedsted, Peter; Fenger-Grøn, Morten

    2012-01-01

    Det er velkendt at der er social gradient i prognosen for diabetes, men det er uklart on denne ulighed også gælder brug af almen praksis blandt personer med diabetes. En nationalt, populationsbaseret kohortestudie blev udført med 137.492 personer med incident diabetes i alderen 40-79 år og 687...... efter diagnose blev sammenlignet. Personer med diabetes havde 4,8 (95%CI:4,7-4,8) flere konsultationer i almen praksis første år efter diagnose. Denne ekstra konsultationsrate steg med faldende SEP; f.eks. 5,8 (95%CI: 5.6-6.0) for kvinder i aldersgruppen 40-54 år med laveste uddannelsesniveau og 4,9 (95......%CI: 4,7-5,1) for kvinder med det højeste uddannelsesniveau. Personer med diabetes havde næsten 5 ekstra konsultationer i almen praksis første år efter diagnoses og antallet var højest for de med lavest SEP....

  16. Implementation of immunochemical faecal occult blood test in general practice

    DEFF Research Database (Denmark)

    Juul, Jakob Søgaard; Bro, Flemming; Hornung, Nete

    2016-01-01

    anvendelsen af immunochemical faecal occult blood test (iFOBT) i almen praksis. iFOBT detekterer humant globin i fæces og indikerer gastrointestinal blødning. Studiet udgør en del af et ph.d.-studie, der bidrager med ny viden til at optimere udredningen af patienter med tarmkræft. Der er et stort behov...

  17. Læringsmål i masteruddannelser – et underviserperspektiv på teori-praksis relationen

    Directory of Open Access Journals (Sweden)

    Annie Aarup Jensen

    2016-10-01

    Full Text Available Artiklen belyser, med udgangspunkt i Ellströms kategorisering af handlings-, videns- og læringsniveauer (1996, at der eksisterer en generel grundlæggende forskel mellem, hvad underviserne oplever, at masterstuderende har som mål med deres uddannelse, og hvad underviserne selv tolker som det overordnede mål. De studerendes mål er ifølge underviserne overvejende at få teoretisk viden og teoretisk funderede svar på konkrete problemstillinger, mens undervisernes mål er at skabe refleksive praktikere gennem arbejdet med teorier og teori-praksis¬inte¬gra¬tion. Artiklen er baseret på kvalitative interviews med fem erfarne underviserer fra tre forskellige masteruddannelser, hvor kernefelterne er læreprocesser, organisations- og professionsudvikling samt lederudvikling. Based on Ellström’s categorization of levels of action, knowledge and learning (1996, the article shows that a fundamental difference exists between master students’ objectives for their education as experienced by the teachers, and the teachers’ own interpretation of the overall objectives. According to the teachers, the students’ objectives are primarily to acquire theoretical knowledge and theoretically based answers or solutions to specific practice related problems, whereas the teachers’ objectives are to create reflective practitioners through their work with theories and theory-practice integration. The article is based on qualitative interviews conducted with five experienced teachers from three different master programmes that focus on learning processes, organizational- and professional development and leadership development.

  18. Relationer mellem teori og praksis i pædagogisk og lærerfagligt arbejde

    DEFF Research Database (Denmark)

    Knudsen, Lars Emmerik Damgaard

    måder, og de hver af disse understøtter bestemte opfattelser af pædagogik og undervisning. Denne bog forsøger derfor give svar på, hvordan du kan forstå og omsætte relationerne mellem teori og praksis i dine pædagogiske studier og aktiviteter. Bogen giver dig viden om: • Hvordan og hvorfor teori og......Forbindelsen mellem teori og praksis er en grundlægende udfordring. Det gælder alle fag og professioner men ikke mindst for lærer- og pædagogstuderende, som netop formidler viden og som denne bog derfor adresserer. Den grundlæggende idé er, at teori og praksis kan relateres på flere forskellige...... praksis relaterer sig til hinanden som forskellige vidensformer, og hvordan disse forskellige former for viden ofte knytter sig til den kultur, som de optræder i. • Hvordan du kan analysere og syntetisere den måde, du i dit eget pædagogiske arbejde relaterer teori og praksis på, så du dermed også kan...

  19. Praksis Pembelajaran Kewirausahaan pada Unit Produksi Jasa Boga

    Directory of Open Access Journals (Sweden)

    Tuatul Mahfud

    2013-01-01

    Full Text Available Abstrak: Praksis pembelajaran kewirausahaan pada unit produksi jasa boga. Penelitian bertujuan menemukan konsepsi guru tentang pembelajaran kewirausahaan, kompetensi kewirausahaan yang dikembangkan pada unit produksi sekolah dalam bidang jasa boga. Penelitian ini menggunakan metode kualitatif jenis studi kasus. Subjek penelitian adalah kepala sekolah, ketua program studi, kepala unit produksi, dan siswa. Data dikumpulkan melalui wawancara, observasi, dan dokumentasi dan dianalisis menggunakan model interaktif dari Miles dan Huberman yang terdiri dari reduksi data, data display, dan kesimpulan. Hasil penelitian menunjukkan bahwa: (1 belajar kewirausahaan memerlukan kegiatan nyata (hands-on dengan melibatkan siswa pada kegiatan usaha yang nyata dalam unit produksi; (2 kompetensi kewirausahaan dikembangkan melalui unit produksi adalah: pengetahuan tentang kewirausahaan melalui pengetahuan diri dan pengetahuan praktis; sikap kewirausahaan meliputi etos kerja, disiplin, kemandirian, dan kreativitas, keterampilan berkomunikasi, keterampilan konseptual, keterampilan pengambilan keputusan, keterampilan mengatur waktu, keterampilan kepemimpinan. Model pembelajaran kewirausahaan yang dikembangkan melalui unit produksi adalah: produksi luar dan produksi dalam, dan kantin mobil. Evaluasi dan monitoring dilakukan melalui dua cara, dengan monitoring kinerja dan produk. Kata Kunci: pembelajaran, entrepreneurship, unit produksi

  20. Musikterapi i psykiatrien – Klinisk praksis, forskning og formidling

    Directory of Open Access Journals (Sweden)

    Lars Ole Bonde

    2012-12-01

    Full Text Available Fra og med 2012 er Musikterapi i psykiatrien med støtte fra FKK forvandlet fra et trykt årsskrift med lang produktionshorisont til et open access tidsskrift med langt kortere ekspeditionstid. Lanceringenaf tidsskriftet og dets nye hjemmeside markeres med denne artikel, hvori der gøres status over den situation, musikterapien i den danske psykiatri befinder sig i netop nu. Der gøres rede for antallet af musikterapeuter ansat i psykiatriens forskellige sektorer og institutioner, klientpopulationer der behandles eller serviceres, og det diskuteres hvilke styrker og svagheder der præger musikterapien i psykiatrien netop nu. Desuden belyses musikterapeuternes teoretiske orientering, konkrete behandlingsformer, henvisningskriterier og diagnostiske forhold. Endelig gøres der statusover igangværende dokumentations- og forskningsprojekter samt publikationer fra de seneste 5 år. Undersøgelsen er baseret på tre delundersøgelser foretaget blandt medlemmer af netværket MIP i 2008, 2009 og 2011.

  1. Sprogfag i forandring - pædagogik og praksis

    DEFF Research Database (Denmark)

    Byram, Michael; Daryai-Hansen, Petra; Henriksen, Birgit

    Om undervisningen i engelsk, tysk og fransk i folkeskolen. Med udgangspunkt i Fælles mål 2009 sættes fokus på omsætningen af uddannelsespolitiske lovkrav og pædagogiske ideer til faktiske læringsprocesser i skolen...

  2. Måling af lydisolation og efterklangstid i praksis

    DEFF Research Database (Denmark)

    Kristensen, J.

    Meddelelsen omhandler undersøgelser af mulighederne for at forbedre reproducerbarheden ved måling af luftlydisolation, trinlydniveau og efterklangstid under betingelser, der svarer til måling i den indflytningsfærdige bygning. Der omtales resultater fra måling med to forskellige udformninger af h...

  3. Immediat indsættelse af enkelttandsimplantater i privat praksis

    DEFF Research Database (Denmark)

    Hartlev, Jens; Kohberg, Peter; Ahlmann, Søren

    2015-01-01

    metode – I alt 55 patienter med 55 enkelttandsimplantater blev inkluderet i undersøgelsen. Behandlingen involverede tandekstraktion, implantatindsættelse, påsætning af et endeligt, individuelt abutment og en provisorisk krone I samme behandlingsseance. Den endelige krone blev efterfølgende påsat efter en...

  4. Fieldbook: Udvikling af embedded systemer & smarte produkter i praksis

    DEFF Research Database (Denmark)

    Jensen, Henrik Valentin; Agesen, Mads Kronborg; Nyman, Ulrik Mathias

    bruger technology road maps, SystemsEngineering og modeller og kommer videre fra klassiske udviklingsdyder som stage gate og krav. Det krydres med cases og bestpractices baseret på gennemgående forskningscases fra GN ReSound A/S, MAN Diesel & Turbo A/S, Terma A/S og Seluxit ApS.Fieldbooken formidler best...

  5. Interview med professor Paul du Gay om bureaukratiets værdi

    DEFF Research Database (Denmark)

    Pors, Anja Svejgaard

    2013-01-01

    Paul du Gay er sociolog og globaliseringsprofessor ved Institut for Organisation på Copenhagen Business School. I hans forskning interesserer han sig blandt andet for bureaukratiet som styreform. Gennem årtier har bureaukratiet været genstand for omfattende kritik for dets langsommelighed......, inhumanitet og manglende fleksibilitet. Paul du Gay har taget til genmæle og forsvarer bureaukratiet som en styreform, der understøtter demokrati. I arbejdet med administration som praksis og faglighed har vi interviewet Paul du Gay om nogle af de centrale pointer i denne forskning. Samtalen kredser om...

  6. Grøn Open Access i Praksis

    DEFF Research Database (Denmark)

    Open Access indikatoren påviste et uudnyttet potentiale på ca 60%, men hvorfor er der så ikke mere Open Access indhold?. I det konkrete arbejde med forskningsregistrering og registrering af post-prints støder bibliotekerne på en række udfordringer, som vanskeliggør institutionernes muligheder...... for at nå de nationale Open Access mål. Det er for eksempel inden for områderne rettigheder og licenser, tilladte Open Access versioner, embargoperioder m.m., at vi støder på problemer. Det er disse meget konkrete udfordringer, der arbejdes med i det kommende DEFF projekt ”Grøn Open Access i praksis”....

  7. Revisors opklaring af besvigelser - Læren af praksis

    DEFF Research Database (Denmark)

    Bloch Christensen, Maria; Kristensen, Rikke Holmslykke; Warming-Rasmussen, Bent

    ansvarsfordelingen. Er det bestyrelsen, direktionen, controllerne eller navnlig den eksterne revisor, som burde have opdaget besvigelsen? Eller burde selskabets medarbejdere have påtaget sig det sociale ansvar at agere som whistleblowers? De berørte parter undskylder sig ofte ved, at den nu afslørede bedrager...... medarbejdere med socialt ansvar (whistleblowers), men også de eksterne, herunder kreditgivere, offentlige kontrolmyndigheder samt økonomiske journalister....

  8. Solvarmeanlæg med naturgaskedel/solbeholder-unit og oliefyr/solbeholder-unit. Ydelser og erfaringer fra praksis

    DEFF Research Database (Denmark)

    Furbo, Simon; Vejen, Niels Kristian; Frederiksen, Karsten Vinkler

    1999-01-01

    of the natural gas burner/oil fired boiler and of the circulation pump of the loop so that the heat left in the loop outside the solar tank after every period of operation is reduced to a minimum.Measurements have been carried out in practice for three solar heating systems based on the new units. Additional......Manufacturers have during the last few years started marketing of newly developed natural gas burner/solar tank- and oil fired boiler/solar tank-units.These units make it possible to reduce the costs of solar heating systems, because an electric heating element is not built into the solar tank...... the pipes connecting the natural gas burner/oil fired boiler and the top spiral of the solar tank and from the natural gas burner/oil fired boiler. Furthermore, the unit with a fixed design of the natural gas burner/oil fired boiler - top spiral loop open up the possibility of an optimum control...

  9. Oversættelsesperspektiver på idéers møde med praksis

    DEFF Research Database (Denmark)

    Scheuer, John Damm

    -netværksteoriens oversættelsesbegreb blevet søgt indarbejdet i ny-institutionel oversættelsesteori ? 2. Hvordan kan forståelsen af oversættelsesprocessen udvikles videre på et empirisk grundlag ? Det konstateres, at Latours definition og idémodellens socialkonstruktivistiske teoretisering af oversættelsesprocessen er blevet taget...

  10. Variation in general practice prostate-specific antigen testing and prostate cancer outcomes

    DEFF Research Database (Denmark)

    Hjertholm, Peter; Fenger-Grøn, Morten; Vestergaard, Mogens

    2015-01-01

    Brugen af prostata-specifikt antigen (PSA) er mangedoblet i dansk almen praksis siden introduktionen i 1990’erne. Dansk Urologisk Selskab anbefaler brug af testen ved relevante symptomer og arvelig disposition, men ikke til screening. Alligevel varierer brugen af PSA-tests i almen praksis. Dette...

  11. MedSun Reports

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Medical Product Safety Network (MedSun) is an adverse event reporting program launched in 2002. The primary goal for MedSun is to work collaboratively with the...

  12. Advancing PubMed?

    DEFF Research Database (Denmark)

    Wildgaard, Lorna Elizabeth; Lund, Haakon

    2016-01-01

    the efficiency of biomedical literature searches. PubMed remains the primary resource for biomedical literature, and as PubMed makes the Medline data and Entrez PubMed Programming utilities freely available, any developer can produce alternative tools to search the database. The authors question if PubMed still...... provides the superior search interface for systematic searches or if the innovativeness of third-party tools provide alternatives worth considering. The paper aims to discuss these issues. Design/methodology/approach In all, 76 third-party tools that build on PubMed content were identified in a PubMed...... search and in published studies known to the authors. Only tools that provided free access to the broad PubMed content and designed specifically to enhance the search were included, reducing the set to 16 tools. The functionality of each tool within the scenario of a systematic search was compared across...

  13. Nostalgitrip med Pikachu

    DEFF Research Database (Denmark)

    Konzack, Lars

    2016-01-01

    Sommeren 2016 vil blive husket for den omsiggribende dille, Pokémon Go, med over 100 millioner downloads. Tusindvis af især børn og unge, men også forældre med barnevogne og hele familier, kunne pludselig ses på gader og stræder, i parker og grønne områder med en smartphone i hånden på jagt efter...

  14. Sammensvorne designere med succes

    DEFF Research Database (Denmark)

    Dickson, Thomas

    2005-01-01

    Den danske tegnestue Komplot Design har for nylig oplevet den ære, at to af deres stole bliver brugt i cafeerne på det nyindrettede Museum of Modern Art i New York. Men det er ikke kun med møbler, de har succes - tegnestuen kaster sig med iver over mange slags produkter.......Den danske tegnestue Komplot Design har for nylig oplevet den ære, at to af deres stole bliver brugt i cafeerne på det nyindrettede Museum of Modern Art i New York. Men det er ikke kun med møbler, de har succes - tegnestuen kaster sig med iver over mange slags produkter....

  15. Processeringsoptimering med Canons software

    DEFF Research Database (Denmark)

    Precht, Helle

    2009-01-01

    . Muligheder i software optimering blev studeret i relation til optimal billedkvalitet og kontrol optagelser, for at undersøge om det var muligt at acceptere diagnostisk billedkvalitet og derved tage afsæt i ALARA. Metode og materialer Et kvantitativt eksperimentelt studie baseret på forsøg med teknisk og...... humant fantom. CD Rad fantom anvendes som teknisk fantom, hvor billederne blev analyseret med CD Rad software, og resultatet var en objektiv IQF værdi. Det humane fantom var et lamme pelvis med femur, der via NRPB’ er sammenlignelig med absorptionen ved et femårigt barn. De humane forsøgsbilleder blev...

  16. Tilpasset opplæring: politisk dragkamp om pedagogisk praksis

    Directory of Open Access Journals (Sweden)

    Eirik S. Jenssen

    2009-11-01

    Full Text Available Tilpasset opplæring er et populært politisk virkemiddel når skolen skal reformeres og gjøres i stand til å møte endrede betingelser. Det er et begrep som hentes frem når politikerne skal nå mål som inkludering, sosial utjevning eller økt læringsutbytte. Evalueringer viser at skoler opplever tilpasset opplæring som et uklart og problematisk begrep. Vi viser i denne artikkelen at lærerne har god grunn til å synes at tilpasset opplæring er vanskelig å praktisere. Dette gjør vi ved å vise hvordan tilpasset opplæring har skiftet meningsinnhold med skiftende regjeringer i perioden 1975 og frem til i dag. Vi har identifisere fire ulike epoker i tilpasset opplæring som hver fremhever ulike sider ved opplæringen og forfekter ulike løsninger.

  17. Social arv, ulighed og dagtilbuds betydning med henblik på mønsterbrydning

    DEFF Research Database (Denmark)

    Jensen, Bente

    i 120 dagtilbud. Programmet har udviklet innovative strategier for professionelles kompetenceudvikling, dvs. et kompetenceudviklingsprogram, der tilbyder deltagerne muligheder for selv at arbejde eksperimenterende med viden om kvalitetsudvikling i dagtilbud, samt værktøjer til at omsætte denne viden...... (uddannelse), og her planlægges innovative strategier for implementering gennem eksperimenter (i praksis). Antagelsen bag programmet er, at en længerevarende og dybtgående tilgang til professionel kompetenceudvikling med fokus på et innovativt perspektiv vil kunne føre til varige fornyelser i dagtilbud og...... undersøgelse af, om modellen for forandring og fornyelse opnår effekt. Resultater viser, at der opnås positive virkninger af professionelles kompetenceudvikling målt på implementering af nye innovative strategier i det pædagogiske arbejde. Teoretisk diskuteres resultaterne i lyset af en begrebsliggørelse om...

  18. Virtuelt skrivebord med open office

    DEFF Research Database (Denmark)

    Nielsen, Kurt Gammelgaard

    2009-01-01

    SDUs erfaringer med projektet Port 22: en virtuel platform med Open Office som kontorpakke til studerende.......SDUs erfaringer med projektet Port 22: en virtuel platform med Open Office som kontorpakke til studerende....

  19. Læringslandskaber for elever med indlæringsvanskeligheder

    DEFF Research Database (Denmark)

    Szulevicz, Thomas

    Baggrund Denne afhandling består af en empirisk undersøgelse af den pædagogiske praksis på Havredal Praktiske Landbrugsskole (HPL). HPL er en mesterlæreinspireret landbrugsuddannelse for unge elever mellem 16-25 år med indlæringsvanskeligheder. HPL fungerer som et moderne landbrug, der drives af...... elever og lærere i fællesskab. Der er 38 indskrevne elever på skolen, der dyrker 140 ha jord og har en besætning på 50 sortbrogede malkekøer i løsdriftsstald, 250 søer samt 10 heste. Elevernes uddannelse og læring er struktureret omkring deres deltagelse i landbrugsaktiviteterne på skolen. HPL er...... observationerne fandt sted i forskningsprojektets første 14 måneder. Herudover er der blevet foretaget kvalitative interviews med 12 elever fra HPL. Heraf blev de 7 af eleverne interviewet à 3 omgange. 7 lærere på HPL er blevet interviewet. Endelig er der blevet foretaget to videoobservationer af en elevs...

  20. Styrkelse af sammenhængen mellem teori og praksis inden for udvalgte samfundsvidenskabelige fag på bioanalytikeruddannelsen

    DEFF Research Database (Denmark)

    Krause-Jensen, Lone; Neubauer, Turi; Landbo, Anne Sofie

    2016-01-01

    Projektet har undersøgt sammenhængen mellem teori og praksis inden for udvalgte samfundsvidenskabelige fag på bioanalytikeruddannelsen. Teoretisk tages udgangspunkt i Goodlads fem perspektiver på curriculumudvikling: Niveau 1 (ideologisk curriculum), niveau 2 (formelt curriculum), niveau 3 (opfat...

  1. Med-E-Tel

    National Research Council Canada - National Science Library

    Lievens, Frank; Jordanova, Malina

    2006-01-01

    .... The Med-e-Tel 2006 conference program covered over 130 presentations on topics such as homecare and health management, healthcare challenges, tele-education, eHealth in developing countries, telecardiology...

  2. PubMed

    Data.gov (United States)

    U.S. Department of Health & Human Services — PubMed comprises more than 26 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to...

  3. Med-E-Tel

    National Research Council Canada - National Science Library

    Lievens, Frank; Jordanova, Malina

    2006-01-01

    ..., and more. The Med-e-Tel 2006 exhibition showcased products and technologies in the areas of medication compliance, home telehealth and vital sign monitoring, clinical software, electronic medical records...

  4. DailyMed

    Data.gov (United States)

    U.S. Department of Health & Human Services — DailyMed provides high quality information about marketed drugs. This information includes FDA labels (package inserts). This Web site provides health information...

  5. PubMed

    CERN Document Server

    PubMed is the National Library of Medicine's search service that provides access to over 10 million citations in MEDLINE, PreMEDLINE, and other related databases, with links to participating online journals.

  6. Leg med vision

    DEFF Research Database (Denmark)

    Munk, Mette; Bertelsen, Katrine

    2011-01-01

    Bogen henvender sig primært til det pædagogiske personale med målgruppen daginstitutioner. Bogen skal stimulere arbejdet med at gøre bevægelse til en integreret del af kulturen i daginstitutioner - at få det pædagogiske personale til - at sætte ord på og spørgsmålstegn ved deres pædagogiske bevæg...

  7. Energirenovering af almene boliger

    OpenAIRE

    Mogensen, Marie Louise; Raundahl, Nina

    2010-01-01

    This report draw on the great potential of energy-savings, which exist in the Danish public housing sector. Public housing organisations are able to set the standard for renovations high, as they are well organized and have a great number of members. The project examines the problem: "What barriers must be overcome, and what potentials can be used to promote energy renovations in the public housing sector? This is illustrated by a case study of a renovated house in Albertslund, which now is C...

  8. Praksis som læringsmetode i ingeniørutdanningen – erfaringer fra ingeniørstudiet i undervannsteknologi - drift og vedlikehold ved Høgskolen i Bergen (HiB

    Directory of Open Access Journals (Sweden)

    Laila Linde Lossius

    2014-05-01

    Full Text Available Norsk ingeniørutdanning har blitt kritisert for å være for teoretisk. Næringslivets hovedorganisasjon (NHO m.fl. startet derfor prosjektet «Lærlingeordning i høyere utdannelse». Høgskolen i Bergen dro nytte av erfaringene derfra, og i 2007 – da bachelorstudiet i undervannsteknologi startet – var forutsetningen at studiet skulle ha stor praksisandel og mye kontakt med lokalt næringsliv. Studiet har blitt Norges mest etterspurte treårige ingeniørstudium. Frafallet har vært lavere enn ved andre ingeniørstudier. Studiet har inneholdt flere praksisformer, hvorav bacheloroppgave i bedrift, ingeniørpraksis og verkstedpraksis ble regnet som de mest utbytterike ut fra svar i spørreundersøkelsene. 72 % av studentene anså praksis som en viktig årsak til at de søkte. Faglig interesse og utsikt til gode jobber var dog viktigst. 71 % av studentene opplevde at praksis underveis ville gjøre dem til bedre ingeniører, mens 55 % mente det hadde innvirkning på at de fullførte studiet. Praksisbedriftene har tjent ved bedret rekruttering, de største opptil 0,7 ansatt per praksisplass. Praksisorganisering er krevende, og kvalitetssikring og oppfølging er viktig for å få et godt resultat. Bedriftsnettverk er gode støttespillere, men skolen må også avsette nok ressurser til arbeidet. Siden skader kan skje i industrien, må forsikringsordninger av studenter i praksis settes på den politiske agendaen slik at regelverket kan endres. Summary Norwegian engineering studies has been criticized of being too theoretical. Bergen University College used experiences from the project “Apprenticeship in higher education” when starting the engineering program in Subsea technology in 2007. Much practice and contact with local industry was requested. The program has become popular and dropout is lower than in comparable programs. Student surveys revealed the most rewarding practice to be a company-based Bachelor thesis, engineer internships and

  9. Tang med omtanke

    DEFF Research Database (Denmark)

    Schlundt, Jørgen

    2013-01-01

    Befolkningen bør kende både mulige positive og negative effekter af fødevarer, før de spiser dem. Det mener Jørgen Schlundt, DTU Fødevareinstituttet, med henvisning til Ole G. Mouritsens kritik af instituttets udmeldinger om tang i det seneste nummer af Aktuel Naturvidenskab.......Befolkningen bør kende både mulige positive og negative effekter af fødevarer, før de spiser dem. Det mener Jørgen Schlundt, DTU Fødevareinstituttet, med henvisning til Ole G. Mouritsens kritik af instituttets udmeldinger om tang i det seneste nummer af Aktuel Naturvidenskab....

  10. Grateful Med: getting started.

    Science.gov (United States)

    Shearer, B; McCann, L; Crump, W J

    1990-01-01

    When a local medical library is not available, it is often necessary for physicians to discover alternate ways to receive medical information. Rural physicians, particularly, can make use of a computer program called Grateful Med that provides access to the same literature available to physicians in large cities. This program permits the user to perform database searches on the National Library of Medicine database (MEDLINE), corresponding to the primary index to medical literature, Index Medicus. In this article, we give the procedure for procuring a National Library of Medicine password and for making efficient use of the Grateful Med program.

  11. At lede med latter

    DEFF Research Database (Denmark)

    Møller, Mette

    2014-01-01

    "Det sagde hun også i går!" Platte vitser, der lægger op til den karakteristiske 'bodom-tchi'-trommelyd, behøver ikke være lederens eneste forsøg på at udvise humoristisk sans på talerstolen. For humor kan være meget andet og gøre meget mere for lederen end at score billige point med en spontan s...... spøg. Humor kan skabe klarhed over en pointe, skabe lederens image og skabe sammenhold i organisationen. Uden trommelyd, men med mange andre effekter i spil....

  12. Selskabsloven med kommentarer

    DEFF Research Database (Denmark)

    Schaumburg-Müller, Peer; Werlauff, Erik

    Selskabsloven med kommentarer er bibelen på området for kapitalselskaber. Den er et juridisk arbejdsredskab for praktikere, rådgivere, forskere og studerende. Bogen indeholder en komplet opdatering af kommentarerne i forhold til de mange ændringer i selskabsloven siden 1.-udgaven, men bygger i øv...

  13. Professionalisme med innovativt potentiale

    DEFF Research Database (Denmark)

    Nielsen, Inger Marie

    To teoretiske sværvægtere bliver koblet sammen i Inger Marie Larsen-Nielsen arbejdspapir om professionalisme med innovativt potentiale. De to teoretikere er læringsteoretikeren John Dewey og socialpsykologen Georg Herbert Mead, som er sat sammen i en teoretisk forståelsesramme omkring professionel...

  14. En definitionssandhed med modifikationer

    DEFF Research Database (Denmark)

    Holtermann, Jakob v. H.; Olsen, Henrik Palmer

    2013-01-01

    Denne artikel indgår i den debat om retskildebegrebet, der tidligere har været rejst af Jens Ravnkilde. Forfatterne påviser flere svagheder i Ravnkildes argumentation, herunder at han ignorerer hele den internationale diskussion på området, samtidig med at han baserer sit eget angiveligt nyudvikl...

  15. At skrive med video

    DEFF Research Database (Denmark)

    Holmboe, Peter

    2018-01-01

    Det kræver særlige kompetencer at skrive en digital tekst, så modtageren kan læse og bruge den. Derfor er det vigtigt at stimulere og udvikle elevernes skrivekompetence med både viden og værktøjer. Digital skrivedidaktik præsenterer teori om skrivekompetence og digital skrivning. Derudover...

  16. Personer med handicap

    DEFF Research Database (Denmark)

    Larsen, Brian; Jonassen, Anders Bruun; Høgelund, Jan

    Regeringens Arbejdsmarkedskommission kommmer medio 2009 med forslag til, hvordan den samlede arbejdsindsats varigt kan øges gennem reformer på arbejdsmarkedet. En måde det kan ske på, er ved at begrænse antallet af personer, der står uden for arbejdsmarkedet som følge af helbredsproblemer. Rappor...

  17. Filosofisk praksis

    DEFF Research Database (Denmark)

    Ziethen, Morten

    2014-01-01

    Within this article I try both to contribute to the development of the philosophical practice as it is known in the tradition from Achenbach and Lindseth and on the other hand to the exegetic research on the later Heidegger. The reason why I combine those two quite different ‘traditions’ is that I...... of Lebenskönnerschaft, so it is argued, is that Heidegger in his later thinking is asking, what humans can do when language is speaking. In other words: What the later Heidegger asks is, what ‘freedom’ or ‘doing’ is, when the subject is not self-positing and not controlling the flux of language and meaning. Along...

  18. Endostatin (EntreMed).

    Science.gov (United States)

    Grosios, K

    2000-07-01

    EntreMed has licensed the worldwide rights to the angiogenesis inhibitor Endostatin, a 20 kDa C-terminal fragment of collagen XVIII, from the Children's Hospital of Boston, a teaching affiliate of Harvard Medical School. It is being developed as a potential cancer treatment and may also be useful in certain types of blindness and arthritis [227427]. EntreMed filed an IND for Endostatin in June 1999 [334125] and as of September 1999, phase I trials were underway [341462]. As of April 2000, the company had initiated plans for testing low doses of Endostatin in cancer patients using continuous infusion and sc administration in a further phase I study to be conducted in Europe [361594]. A phase I trial of Endostatin which will evaluate the safety and efficacy of Endostatin at a range of doses in no more than 100 cancer patients has been initiated. The trial will take place at the University of Texas MD Anderson Medical Center and the University of Wisconsin Cancer Center in Madison. The National Cancer Center will be sponsoring the trial, which is expected to be completed in late 2000. As of March 2000, there had been no serious adverse events attributable to Endostatin administration. The first report from this trial is expected in autumn 2000 [341462], [366312]. The mechanism of action for Endostatin remains unclear, although reports from the 91st AACR Meeting in April 2000 showed that recombinant human endostatin bound to a number of tropomyosin cDNAs in a library screen [362039]. In preclinical studies, repeated administration of Endostatin consistently shrank primary tumors and did not produce any drug resistance. In mice, a variety of tumors which had progressed to 1 to 2% of total body weight, regressed to microscopic, dormant lesions following Endostatin treatment [231418], [231470], [270673]. Types of cancers which respond to Endostatin include lung, skin, vascular and fibrosarcomas. Toxicology studies in cynomolgus monkeys showed that bolus injections of

  19. Farlig sex med engle

    DEFF Research Database (Denmark)

    Mejrup, Kristian

    2013-01-01

    De fleste af os tænker ikke på engle som kønnede væsner med en seksualitet, og selv om vi er i stand til at acceptere engle i alle mulige afskygninger, fra juletræets tyksakker i glitrende guld til frygtindgydende skikkelser i de bibelske skrifter, så er vi tilbøjelig til at ignorere spørgsmålet ...

  20. Sammenhængende diabetesforløb

    DEFF Research Database (Denmark)

    Bødker, Keld

    2006-01-01

    Sundhedsstyrelsen har i foråret 2006 offentliggjort en rapport, udarbejdet i fællesskab med konsulentfirmaet MEDIQ, omhandlende etablering af et it-system til støtte for sammenhængende patientforløb indenfor diabetesbehandling (Sundhedsstyrelsen 2006). Rapporten præsenterer sig som at give...... "analysegrundlaget" for et nationalt diabetes informationssystem. Systemet foreslås realiseret som et web-baseret system, der kan bidrage til informations- og videndeling mellem almen praksis, diabetesambulatorierne og Sundhedsstyrelsen. Målsætningen er, at systemet implementeres som en applikation i regi af sundhed...

  1. Predictive values of GPs' suspicion of serious disease

    DEFF Research Database (Denmark)

    Hjertholm, Peter; Moth, Grete; Ingeman, Mads Lind

    2014-01-01

    Denne artikel undersøger hyppigheden af praktiserende lægers mistanke om kræft eller anden alvorlig sygdom hos patienter i konsultationen. Dertil om mistanken fører til en alvorlig diagnose og patientens brug af det øvrige sundhedsvæsen. Lægen havde mistanke i 5,7 % af alle konsultationer, og en ...... data fra KOS 2008-undersøgelsen (Kontakt- og sygdomsmønsteret i almen praksis), hvor 404 praktiserende læger registrerede 4518 konsultationer med personer over 18 år....

  2. MedPAC Data Book

    Data.gov (United States)

    U.S. Department of Health & Human Services — MedPACs Data Book is the result of discussions with congressional staff members regarding ways that MedPAC can better support them. Some of the information it...

  3. Idrætsstuderendes læring af aktionsforskning i et samarbejde med erhvervsskolelærere

    DEFF Research Database (Denmark)

    Elbæk, Lars

    foregå, således at forskningsbaseret bevægelsesviden oversættes til daglig praksis på erhvervsskoleområdet. Da idrætsstuderende i fremtidige jobs kan forventes at skulle være med til at oversætte viden til praksis, fremlægges I denne præsentation et studie af idrætsstuderendes omsætning af viden til...... teacher-educators practice action research as they introduce action research to preservice teachers. Action Research, 6(1), 7-28. doi:10.1177/1476750307083716 Straus, S. E., Tetroe, J., & Graham, I. (2009). Defining knowledge translation. Canadian Medical Association Journal, 181(3-4), 165-168. Retrieved...... from http://www.cmaj.ca/content/181/3-4/165.short Turner, S. A. (2010). Teaching Research to Teachers: A Self-Study of Course Design, Student Outcomes, and Instructor Learning. Journal of the Scholarship of Teaching and Learning, 10(2), 60-77. Virginia Braun, Victoria Clarke, Paul Weate (2016), Using...

  4. Granice teritorijalnog mora u nacionalnim propisima i praksi obalnih država Sredozemlja

    Directory of Open Access Journals (Sweden)

    Marina Vokić Žužul

    2009-08-01

    Full Text Available U radu se razmatra primjena pravila Konvencije UN-a o pravu mora iz 1982. o vanjskoj granici, širini i razgraničenju teritorijalnog mora u nacionalnim propisima i praksi obalnih država Sredozemlja. Posebna pozornost posvećena je pitanjima vezanim uz proširenje granica suverenosti Grčke i Turske u Egejskome moru, čija su teritorijalna mora još uvijek široka šest milja. Dvostranim ugovorima između država čije obale leže sučelice ili međusobno graniče u Sredozemlju je do danas konačno definirano samo šest granica teritorijalnih mora. Sadržaj svakog od ugovora kojima je razgraničeno teritorijalno more - između Cipra i suverenih vojnih baza Velike Britanije na tome otoku, između bivšeg Sovjetskog Saveza i Turske, između bivše SFRJ i Italije te između Francuske i Italije u tjesnacu Bonifacio - predmet je posebne analize. Razmatraju se također i sporazumi o jedinstvenoj morskoj granici između Bugarske i Turske te Francuske i Monaka, kojima su uz teritorijalno more razgraničeni i drugi morski prostori.

  5. Læringsmål i Masteruddannelser– et underviserperspektiv på teori-praksis relationen

    DEFF Research Database (Denmark)

    Jensen, Annie Aarup; Thomassen, Anja Overgaard

    2016-01-01

    Artiklen belyser, med udgangspunkt i Ellströmskategorisering af handlings-, videns- og læringsniveauer (1996), at der eksisterer en generel grundlæggende forskel mel-lem, hvad underviserne oplever, at masterstuderende har som mål med deres ud-dannelse, og hvad underviserne selv tolker som det...

  6. Global Health Care-seeking Discourses Facing Local Clinical Realities

    DEFF Research Database (Denmark)

    Andersen, Rikke Sand; Tørring, Marie Louise; Vedsted, Peter

    2014-01-01

    På baggrund af et længerevarende feltarbejde i danske klinikker i almen praksis undersøger denne artikel forholdet mellem forebyggelsesorienterede diskurser om lægesøgning og − hvad der betragtes som − legitime lægesøgningspraksisser på klinik-niveau. Forfatterne argumenterer for, at der i almen ...

  7. Symptoms as the main problem

    DEFF Research Database (Denmark)

    Rosendal, Marianne; Carlsen, Anders Helles; Rask, Mette Troellund

    2016-01-01

    Dette studie undersøger tilfredsheden hos patienter, der blev afsluttet i almen praksis uden specifik diagnose, dvs. hvor lægen efter afsluttet konsultation kun kunne anføre "symptom" eller "problem" som slutdiagnose. Det drejer sig om ca. 1/3 af alle helbredsrelaterede konsultationer i almen...

  8. The MedDRA paradox.

    Science.gov (United States)

    Merrill, Gary H

    2008-11-06

    MedDRA (the Medical Dictionary for Regulatory Activities Terminology) is a controlled vocabulary widely used as a medical coding scheme. However, MedDRA's characterization of its structural hierarchy exhibits some confusing and paradoxical features. The goal of this paper is to examine these features, determine whether there is a coherent view of the MedDRA hierarchy that emerges, and explore what lessons are to be learned from this for using MedDRA and similar terminologies in a broad medical informatics context that includes relations among multiple disparate terminologies, thesauri, and ontologies.

  9. Gruppemusikterapi med patienter med borderline-personlighedsforstyrrelse i dagbehandlingsregi

    DEFF Research Database (Denmark)

    Hannibal, Niels

    2008-01-01

    Denne artikel er første redegørelse for de erfaringer, som er gjort med gruppemusikterapi (GMT) for patienter med borderline-personlighedsforstyrrelse (BPF) i dagbehandlingsregi på Aalborg Psykiatriske Sygehus. Artiklen indeholder både konkrete anvisninger til aktiviteter og interventioner, liges...

  10. Tankeløs testning: Betragtninger om succes, formål og meningen med at holde skole

    Directory of Open Access Journals (Sweden)

    Stig Skov Mortensen

    2016-03-01

    Full Text Available De nationale test har fået en ny rolle som grundlag for vurderingen af skolens succes. Dermed flyttes fokus fra folkeskolens brede dannelseshorisont, som den kommer til udtryk i fx formålsparagraffen, og i denne artikel vil jeg identificere 4 afledte, potentielle problemer ved udviklingen. Problemerne er ikke skarpt adskilte, men viser på hver sin måde en væsentlig pædagogisk faldgrube. Slutteligt vil jeg skitsere et bud på, hvordan evalueringsforskning kan være med til at vende denne udvikling således, at skolen – og ikke mindst dens pædagogiske praksis – kan opfattes som byggende på nogle formål, der har værdi i sig selv.

  11. Fra kollegial supervision til fællesfaglig udvikling - et eksperiment med entreprenørskabsundervisning i faget Kulturformidling

    DEFF Research Database (Denmark)

    Elbeshausen, Hans; Jensen, Agnete Lunddahl; Riis, Ragnhild

    2013-01-01

    . Deres involvering viste sig i dialogiske interventioner i undervisningens form og indhold. This article presents an explorative journey carried out by a team of teachers. The aim was to develop their teaching methods in master courses in communication by integrating entrepreneurial thinking. The focus......Artiklen handler om at tilegne sig viden om entreprenørskab som undervisningsform gennem en eksperimentel praksis. Vi beskriver udfordringer, dilemmaer, erfaringer og vendepunkter i forløbet og forklarer, hvordan fokus i den kollegiale supervision flyttede til at udvikle faglighed i fællesskab....... Forløbets eksplorative og fleksible form blev ledsaget af dialog på flere niveauer og inddrog både de studerende og alle undervisere. Målene kunne præciseres og ændres, og institutionens faglighed udvides. Med metaforen ’tvillinger’ blev kolleger indbudt til særligt at følge underviserne i eksperimentet...

  12. Med det sociale som designmateriale

    DEFF Research Database (Denmark)

    Brandt, Eva; Binder, Thomas

    2016-01-01

    Samarbejde, samskabelse og social nysgerrighed er i dag en præmis for den nyskabende designer. Det sociale er det nye designmateriale som unge designere giver sig i kast med når f.eks. Emmy Linde samarbejder med plejehjemsbeboere, deres pårørende, plejepersonale og fysioterapeuter for at designe ...

  13. Fagligt Indstik: Jordemødres holdninger til og praksis omkring sene provokerede aborter

    DEFF Research Database (Denmark)

    Christensen, Anne Vinggaard

    2012-01-01

    gennemgår en sen provokeret abort. I en række interviews undersøgtes jordemødres erfaringer med og holdninger til udførelsen af sene provokerede aborter. Interviewene samt en gennemgang af procedurer på en række danske hospitaler viste, at der er mange følelser forbundet med udførelsen af en sen provokeret...

  14. Boost læringen med levende billeder

    DEFF Research Database (Denmark)

    Christensen, Ole

    2016-01-01

    Børn og unge lever i en digital virkelighed, og det er helt afgørende, at skolerne møder denne virkelighed. Medierne har nemlig både potentialet for at understøtte og udfordre den pædagogiske praksis......Børn og unge lever i en digital virkelighed, og det er helt afgørende, at skolerne møder denne virkelighed. Medierne har nemlig både potentialet for at understøtte og udfordre den pædagogiske praksis...

  15. Lærende møder og konferencer i praksis

    DEFF Research Database (Denmark)

    Ravn, Ib; Elsborg, S.

    ? Frokost der skaber kontakter ? Plukke det bedste i plenum ? To gratis konsulenter Bogen er baseret på resultater fra forsknings- og udviklingsprojektet ?Det lærende møde?. Det blev gennemført af Learning Lab Denmark ved Danmarks Pædagogiske Universitet i samarbejde med Danske Bank, Rezidor SAS Hospitality...

  16. Fra teori til praksis - om evaluering af arbejdsmiljøindsatser i en ustyrlig virkelighed

    DEFF Research Database (Denmark)

    Hasle, Peter; Nielsen, Klaus T.; Limborg, Hans Jørgen

    indsats, outcome er de umiddelbare virkninger indsatsen har over for målgruppen, mens impact er den mere langsigtede virkning. Af pragmatiske grunde evalueres ofte på outputs af indsatser, fx antal downloads af en given BAR-vejledning. Disse outputs må dog ikke forveksles med opnåelse af det ønskede...

  17. MENYOAL KESENJANGAN ANTARA DAS SOLLEN ISLAM DENGAN DAS SEIN PRAKSIS KEHIDUPAN KAUM MUSLIMIN

    Directory of Open Access Journals (Sweden)

    Yusuf Suyono

    2016-03-01

    itu dikarenakan Islam telah menjadi darahnya sehingga beliau adalah cermin dan etalase Islam par excellence. Kaum Muslimin, sebagai pengikutnya, belum mampu berbuat seperti uswah mereka itu. Al-Amir Syakib Arsalan, Muhammad Abduh, Mohammad Iqbal, Muhammad al-Ghazali, Hassan Hanafi telah berusaha menformulasikan bagaimana menjembatani jurang pemisah antara Das Sollen dan Das Sein kaum Muslimin itu. Semuanya itu karena didorong oleh keprihatinan melihat betapa dalam dan menganganya jurang antara Das Sein praksis kehidupan Umat Islam dengan Das Sollen ajaran Islam yang ya’lu wa lā yu’lā ‘alaih itu. Sementara di saat yang bersamaan mereka melihat betapa etos beruf Calvinisme bisa mendorong etos Kapitalis¬me modern bagi pemeluknya di Eropa Barat, etos Buddha Zen bisa mendorong bangsa Jepang menjadi macan Asia, dan spirit Konfucian (Kong Hu Cu mendorong bangsa Korea menjadi dragon Asia. Keywords:filsafat Islam, dialektika sirkular, etika Islam, filsafat Iqra’, Das Sollen, dan Das Sein.

  18. Med Antony Beevor i Ardennerne

    DEFF Research Database (Denmark)

    Christensen, Claus Bundgård

    2015-01-01

    Den storsælgende amerikanske historiker Antony Beevor tager i sin gennemgang af Anden Verdenskrigs slag denne gang læserne med til de sneklædte skove i Ardennerne, hvor tyskerne iværksatte deres sidste store offensiv på Vestfronten.......Den storsælgende amerikanske historiker Antony Beevor tager i sin gennemgang af Anden Verdenskrigs slag denne gang læserne med til de sneklædte skove i Ardennerne, hvor tyskerne iværksatte deres sidste store offensiv på Vestfronten....

  19. Ud at se med Erasmus

    DEFF Research Database (Denmark)

    Frandsen, Pernille

    2009-01-01

    Få lidt luft under vingerne, kom ud at møde udenlandske kolleger og se, hvordan man også kan lave uddannelsesbibliotek. Med begejstring fortæller tre bibliotekarer om deres oplevelser i det store udland – alt sammen finansieret af Erasmus.......Få lidt luft under vingerne, kom ud at møde udenlandske kolleger og se, hvordan man også kan lave uddannelsesbibliotek. Med begejstring fortæller tre bibliotekarer om deres oplevelser i det store udland – alt sammen finansieret af Erasmus....

  20. Tandlægers erfaringer med at foreslå og få gennemført behandling med kroner og broer i privat praksis [Experiences of Danish dentists in private practice in motivating treatment with crowns and bridges

    DEFF Research Database (Denmark)

    Isidor, F.; Moore, R.

    2003-01-01

    and bridges, or lack of success in getting treatment completed hung mostly with practice type and location. Almost 76% of the dentists felt that it should be possible to learn how to motivate patients for the expensive treatments (eg bridges). More than 90% of the dentists felt the need for a better insurance...

  1. Aktionslæring som metode til udvikling af inkluderende praksis

    DEFF Research Database (Denmark)

    Olsson, Janne; Maltzahn, Lene Nyboe

    2014-01-01

    Kapitlet handler om, hvordan genkendelige hverdagspraksisser i daginstitutioner i nogle tilfælde ekskluderer børn, mens andre praksisser understøtter, at børn kan tage del i fællesskaber. Med afsæt i en konkret case argumenteres der for, at aktionslæring som metode kan gøre det muligt for pædagog...

  2. INTEGRATIV GESTALT PRAKSIS - IGP : EN RAMME FOR FORSTÅELSE AF FORHOLDET MELLEM TERAPI OG COACHING

    Directory of Open Access Journals (Sweden)

    Mikael Sonne

    2017-01-01

    Full Text Available Jeg vil i denne artikel præsentere gestalttilgangens teoretiske og praktiske grundstruktur. Der vil endvidere blive redegjort for, hvordan gestalttilgangens feltteori, med inspiration fra Ken Wilber’s integrale perspektivisme (Wilber 1995; 2000; 2006, kan danne grundlag for en integrativ rammesætning for forskellige psykologiske og psykoterapeutiske tilgange, samt for en forståelse af forholdet mellem terapi og coaching.

  3. Spilleregler i musikterapi med voksne

    DEFF Research Database (Denmark)

    Holck, Ulla

    2005-01-01

    Artiklen gennemgår udvalgt faglitteratur, der på et overordnet plan beskriver typer af spilleregler i musikterapi med (fortrinsvis) voksne klientgrupper. Udgangspunktet er Priestleys anvendelse af begrebet, og hendes inddeling af spilleregler i forhold til forskellige teknikker gennemgås, efterfu...

  4. Mediator Complex Subunits MED2, MED5, MED16, and MED23 Genetically Interact in the Regulation of Phenylpropanoid Biosynthesis.

    Science.gov (United States)

    Dolan, Whitney L; Dilkes, Brian P; Stout, Jake M; Bonawitz, Nicholas D; Chapple, Clint

    2017-12-01

    The phenylpropanoid pathway is a major global carbon sink and is important for plant fitness and the engineering of bioenergy feedstocks. In Arabidopsis thaliana , disruption of two subunits of the transcriptional regulatory Mediator complex, MED5a and MED5b, results in an increase in phenylpropanoid accumulation. By contrast, the semidominant MED5b mutation reduced epidermal fluorescence4-3 ( ref4-3 ) results in dwarfism and constitutively repressed phenylpropanoid accumulation. Here, we report the results of a forward genetic screen for suppressors of ref4-3. We identified 13 independent lines that restore growth and/or phenylpropanoid accumulation in the ref4-3 background. Two of the suppressors restore growth without restoring soluble phenylpropanoid accumulation, indicating that the growth and metabolic phenotypes of the ref4-3 mutant can be genetically disentangled. Whole-genome sequencing revealed that all but one of the suppressors carry mutations in MED5b or other Mediator subunits. RNA-seq analysis showed that the ref4-3 mutation causes widespread changes in gene expression, including the upregulation of negative regulators of the phenylpropanoid pathway, and that the suppressors reverse many of these changes. Together, our data highlight the interdependence of individual Mediator subunits and provide greater insight into the transcriptional regulation of phenylpropanoid biosynthesis by the Mediator complex. © 2017 American Society of Plant Biologists. All rights reserved.

  5. The MedCLIVAR Network

    Science.gov (United States)

    Lionello, Piero; Medclivar sg, The

    2013-04-01

    The MedCLIVAR initiative was first proposed at the 2003 European Geosciences Union assembly in Nice, France. In 2005, it was endorsed by the International Climate Variability and Predictability (CLIVAR) office. Subsequently, the MedCLIVAR Research Network Project was formally approved by the European Science Foundation and launched in May 2006 with the support of funding agencies from 12 countries. Since then, MedCLIVAR has served as a scientific network to promote interaction among different scientific disciplines and to develop a multidisciplinary vision of the evolution of the Mediterranean climate through studies that integrate atmospheric, marine, and terrestrial climate components at time scales ranging from paleoreconstructions to future climate scenarios. Presently, the network continues dealing with scientific issues including past climate variability; connections between the Mediterranean and global climate; the Mediterranean Sea circulation and sea level; feedbacks on the global climate system; and regional responses to greenhouse gas, air pollution, and aerosols. Its present activities include the publication of a newsletter, the organization of the next MedCLIVAR conference in 2014 and the publication of a special issue of Regional Environmental Change devoted to the climate of the Mediterranean region.

  6. MANUAL FOR PROCESORIENTERET MUSIKTERAPI MED PERSONER MED BPD.

    Directory of Open Access Journals (Sweden)

    Niels Hannibal

    2010-12-01

    Full Text Available Denne artikel introducerer et musikterapeutisk behandlingskoncept kaldet: Procesorienteret Musikterapi (PROM. PROM er et forsøg på at formulere en principiel ramme for musikterapi i psykiatrien, som dels tager udgangspunkt i 17 års klinisk erfaring, dels stiler mod at være ”best practice”. PROM indeholder beskrivelser af manualens unikke, essentielle men ikke unikke, acceptable og ikke acceptable dele. Den unikke del af PROM skal kunne implementeres til alle målgrupper, mens de øvrige dele af manualen rettes til i forhold til en specifik målgruppe. Denne udgave af PROM er specifikt rettet i mod musikterapi for patienter med personlighedsforstyrrelser. Manualen indgår også som en del af et pilotprojekt, der har til formål at udvikle en protokol for et internationalt RCT projekt med samme målgruppe

  7. Gruppemusikterapi med patienter med borderline-personlighedsforstyrrelse i dagbehandlingsregi

    Directory of Open Access Journals (Sweden)

    Niels Hannibal

    2008-05-01

    Full Text Available Denne artikel er første redegørelse for de erfaringer, som er gjort med gruppemusikterapi (GMT for patienter med borderline-personlighedsforstyrrelse (BPF i dagbehandlingsregi på Aalborg Psykiatriske Sygehus. Artiklen indeholder både konkrete anvisninger til aktiviteter og interventioner, ligesom den i et teoretisk perspektiv redegør for forskellige processer og reaktioner, der kan iagttages i behandlingen. Artiklen konkluderer, at GMT i sin nuværende form kan bidrage til udvikling af BPF-patienters evne til mentalisering og affektregulering, til opbygning af en gruppefølelse og fremme af interpersonel læring, ligesom GMT kan udvikle alliance til terapi generelt og GMT specifikt.

  8. Med Kingo på dybt vand

    DEFF Research Database (Denmark)

    Arndal, Lars Stubbe

    2014-01-01

    Tag med digteren Thomas Kingo ud på dybt vand i selskab med lektor og mag.art. Lars Arndal, der kaster nye perspektiver på Kingos forlisdigt Hierte-Suk. Arndal kommer hermed også med et bud på, hvordan man som lærer kan invitere eleverne med på opdagelse i digtet...

  9. Ny viden begynder med forhindringer

    DEFF Research Database (Denmark)

    Johansen, Martin Blok

    2017-01-01

    Pædagogik og pædagogisk arbejde diskuteres typisk inden for rammerne af det at hjælpe, støtte, simplificere og kompleksitetsreducere. Hvis man ønsker at vide noget om forhindringer, modstand og vanskeligheder som pædagogiske muligheder, så er udbuddet derimod forsvindende småt. Og når sådanne...... begreber endelig tages op, så benævnes de typisk blot, men bliver sjældent defineret. Hvad menes der med modstand, vanskeligheder eller kompleksitet? Med afsæt i en kort gennemgang af eksisterende forskning på området forsøger denne artikel at give et bud på en mulig definition af begrebet forhindring...

  10. Effektivisering av arbetet med rumsbeskrivningar

    OpenAIRE

    Enström, Magnus

    2016-01-01

    För att ta byggbranschen till nästa steg i utvecklingen är BIM det naturliga steget. Iteorin tycks många av lösningarna som medföljer implementationen av BIM varaenkla att förstå och skapa, i praktiken ligger dock de tekniska lösningarna långt ifrånen full implementation i branschen. I arbetet med olika typer av beskrivningar inomett byggprojekt har utvecklingen med hjälp av BIM stått still länge. Då det inte finnsnågot vedertaget sätt att utnyttja en BIM-modells information för att fylla oli...

  11. Fang CO2 med Aminosyrer

    DEFF Research Database (Denmark)

    Lerche, Benedicte Mai

    2010-01-01

    Med såkaldte “carbon capture-teknikker” er det muligt at rense røgen fra kulfyrede kraftværker, således at den er næsten helt fri for drivhusgassen CO2. Kunsten er at gøre processen tilstrækkeligt billig. Et lovende fangstredskab i denne proces er aminosyrer.......Med såkaldte “carbon capture-teknikker” er det muligt at rense røgen fra kulfyrede kraftværker, således at den er næsten helt fri for drivhusgassen CO2. Kunsten er at gøre processen tilstrækkeligt billig. Et lovende fangstredskab i denne proces er aminosyrer....

  12. Et eller andet med sprog

    DEFF Research Database (Denmark)

    Adamsen, Billy; Nielsen, Charlotte Marie Bisgaard; Dam Christensen, Mie

    2012-01-01

    bedre sted, intet mindre. - Jeg frygter at de kommer til at kede sig på et reklamebureau med fx at lave kampagner og drikke champagne. Så jeg prøver at tale dem fra det. De skal finde ud af, hvem de er og hvad de gerne vil bruge deres liv på. Rådgiver for statsministeren Billy Adamsen har en phd i...

  13. Veiledning i praksis. Om praksisopplæring i norsk allmennlærerutdannelse

    Directory of Open Access Journals (Sweden)

    Kaare Skagen

    2009-05-01

    Full Text Available Artikkelen presenterer to nyere studier av veiledning i praksisopplæring i allmennlærerutdannelsen. Hovedfunnene drøftes i forhold til noen tidligere nordiske forskningsstudier. Studiene redegjør for intensjoner og realiteter i praksisopplæringen med fokus på mål, innhold og form i praksisveiledningen. Materialet er ramme- og fagplaner og intervjuer og observasjoner ved tre praksisskoler. Veiledningen drøftes i forhold til teori om veiledning. De to studiene som presenteres, konkluderer med at avstanden mellom teoridel og praksisdel i lærerutdannelsen fortsatt eksisterer. Det blir konstatert både fellestrekk og forskjeller mellom skolene når det gjelder graden av individuell veiledning og gruppeveiledning og individuell studentundervisning. Innholdsfokus i veiledningen varierte. Veilederrollen varierte mellom ettergivenhet og pågåenhet. Noen forskningsstudier hevder at øvingslærere praktiserer teknologisk veiledning. Artikkelen argumenterer for at innvielse i undervisningstradisjonen er nødvendig.

  14. Interview med børn

    DEFF Research Database (Denmark)

    Interview med børn handler om børneinterview i forbindelse med forskning. Bogen er tænkt som inspiration til og afsæt for metodiske refleksioner i forbindelse med inddragelse af børn som informanter.......Interview med børn handler om børneinterview i forbindelse med forskning. Bogen er tænkt som inspiration til og afsæt for metodiske refleksioner i forbindelse med inddragelse af børn som informanter....

  15. Human melioidosis reported by ProMED

    Directory of Open Access Journals (Sweden)

    Katherinn Melissa Nasner-Posso

    2015-06-01

    Conclusions: Internet-based reporting systems such as ProMED are useful to gather information and synthesize knowledge on emerging infections. Although certain areas need to be improved, ProMED provided good information about melioidosis.

  16. Towards PubMed 2.0.

    Science.gov (United States)

    Fiorini, Nicolas; Lipman, David J; Lu, Zhiyong

    2017-10-30

    Staff from the National Center for Biotechnology Information in the US describe recent improvements to the PubMed search engine and outline plans for the future, including a new experimental site called PubMed Labs.

  17. Sundhedsmappen.dk

    DEFF Research Database (Denmark)

    Christensen, Kaj Sparle; Mortensen, Marie; Beyer, Hanne

    2013-01-01

    arkiveret i lægens journalsystem. Med etableringen af Sundhedsmappen.dk ønsker vi at digitalisere disse instrumenter for at forbedre kvalitet og tilgængelighed af data. Ideen med Sundhedsmappen.dk er at skabe et onlinesystem, som samler psykometriske test og andre diagnostiske skemaer til brug i almen...... praksis - i et fælles elektronisk bibliotek, som både lægen og patienten har adgang til. De første skemaer, der bliver stillet rådighed, er Major Depression Inventory (MDI) og Angst Symptom Skemaet (ASS) til diagnostik og monitorering af depression og angsttilstande. Sundhedsmappen.dk, der er oprettet på...

  18. Lærere arbejder med landskabsdannelse

    DEFF Research Database (Denmark)

    2012-01-01

    Valg af materiale/medie/form: YOUtube videoklip. Valg af arbejdsform: Lærere der er igang med at afprøve praktisk undersøgende arbejde med danske landskabsformer. Begrundelse for valg af materiale/medie/form/arbejdsform: Ultrakort videoklip valgt så 1) lærerne kan dele med kolleger, 2) øvrige...

  19. Musikalsk leg med formgivning, timing og vitalitetsformer

    DEFF Research Database (Denmark)

    Holck, Ulla

    2015-01-01

    Ifølge de Udviklingsorienterede Social-Pragmatiske Interventionsformer til børn med Autisme Spektrum Forstyrrelse er en legende indfaldsvinkel, hvor man følger barnets lead, den mest effektive til at engagere yngre børn med autisme eller børn med svær autisme i et gensidigt samspil. Artiklen...

  20. Hvordan er det å leve med CRPS?

    OpenAIRE

    Hovind, Thomas

    2014-01-01

    Hensikten med denne studien er å se på hvordan pasienter med komplekst regionalt smertesyndrom (CRPS) opplever å leve med tilstanden og hvordan disse pasientene har opplevd å bli møtt i helsevesenet. CRPS er en langvarig tilstand med sterke smerter som kan medføre økt smerterespons, redusert funksjon og nedsatt livskvalitet hos pasientene. Studien er en kvalitativ undersøkelse basert på dybdeintervju av fire pasienter med CRPS. Pasientene ble rekruttert fra en smerteavdeling i Nord-Norge og u...

  1. Ulykke med hækkesaks

    DEFF Research Database (Denmark)

    Leth, Peter Mygind

    1996-01-01

    Snitsår med blødning fra en overskåret pulsåre på armen forekommer hyppigt ved selvmordsforsøg, men har sjældent et dødeligt forløb. Her gives et eksempel på en isoleret partiel overklipning af a.ulnaris ved en ulykke med en hækkesaks med dødelig forløbende blødning.......Snitsår med blødning fra en overskåret pulsåre på armen forekommer hyppigt ved selvmordsforsøg, men har sjældent et dødeligt forløb. Her gives et eksempel på en isoleret partiel overklipning af a.ulnaris ved en ulykke med en hækkesaks med dødelig forløbende blødning....

  2. Redefining the MED13L syndrome

    OpenAIRE

    Adegbola, Abidemi; Musante, Luciana; Callewaert, Bert; Maciel, Patricia; Hu, Hao; Isidor, Bertrand; Picker-Minh, Sylvie; Le Caignec, Cedric; Delle Chiaie, Barbara; Vanakker, Olivier; Menten, Björn; Dheedene, Annelies; Bockaert, Nele; Roelens, Filip; Decaestecker, Karin

    2015-01-01

    Congenital cardiac and neurodevelopmental deficits have been recently linked to the mediator complex subunit 13-like protein MED13L, a subunit of the CDK8-associated mediator complex that functions in transcriptional regulation through DNA-binding transcription factors and RNA polymerase II. Heterozygous MED13L variants cause transposition of the great arteries and intellectual disability (ID). Here, we report eight patients with predominantly novel MED13L variants who lack such complex conge...

  3. Opfattelser af integration blandt unge med migrantbaggrund

    DEFF Research Database (Denmark)

    Skytte, Marianne; Bryderup, Inge

    2014-01-01

    I artiklen formidles analyser af otte interview med unge med migrantbaggrund. Der er fokus på de unges oplevelser og opfattelser af integration. Der er tale om komplekse processer og vekselvirkninger i forholdet mellem de samfundsmæssige kategoriseringer og individernes selvopfattelser. De unge o...

  4. Automation med pneumatiske servodrev - status og fremtid

    DEFF Research Database (Denmark)

    Sørensen, Paul Haase

    1996-01-01

    Der er råd for problemer med ulineariteter. Med de nyeste metoder kan der lineære driftsområde udvides. Men pneumatikkomponenter skal være af høj kvalitet, når positionering skal være nøjagtig....

  5. Mødet med det Andet

    DEFF Research Database (Denmark)

    Marchwinski, Alena

    2002-01-01

    Da Christen Købke i 1830 malte sitt bilde fra Kunstakademiets avstøpningssamling på Charlottenborg, skildret han en situasjon som vordende danske kunstnere hadde vært fortrolige med i flere generasjoner: en ung mann betrakter en avstøpning av en antikk skulptur. Med utgangspunkt i kombinasjonen a...

  6. Specifik mutation med nålestiksoperation

    DEFF Research Database (Denmark)

    Holme, Inger; Wendt, Toni; Brinch-Pedersen, Henrik

    2014-01-01

    Mutanter af byg er vigtige i forskningen og benyttes også, når der forædles nye sorter til dyrkning. Hidtil har det kun været muligt at inducere mutationer tilfældige steder i genomet. Med helt ny teknologi benyttes proteiner med betegnelsen TALENs til at inducere mutationer i helt specifikke...

  7. Redefining the MED13L syndrome.

    Science.gov (United States)

    Adegbola, Abidemi; Musante, Luciana; Callewaert, Bert; Maciel, Patricia; Hu, Hao; Isidor, Bertrand; Picker-Minh, Sylvie; Le Caignec, Cedric; Delle Chiaie, Barbara; Vanakker, Olivier; Menten, Björn; Dheedene, Annelies; Bockaert, Nele; Roelens, Filip; Decaestecker, Karin; Silva, João; Soares, Gabriela; Lopes, Fátima; Najmabadi, Hossein; Kahrizi, Kimia; Cox, Gerald F; Angus, Steven P; Staropoli, John F; Fischer, Ute; Suckow, Vanessa; Bartsch, Oliver; Chess, Andrew; Ropers, Hans-Hilger; Wienker, Thomas F; Hübner, Christoph; Kaindl, Angela M; Kalscheuer, Vera M

    2015-10-01

    Congenital cardiac and neurodevelopmental deficits have been recently linked to the mediator complex subunit 13-like protein MED13L, a subunit of the CDK8-associated mediator complex that functions in transcriptional regulation through DNA-binding transcription factors and RNA polymerase II. Heterozygous MED13L variants cause transposition of the great arteries and intellectual disability (ID). Here, we report eight patients with predominantly novel MED13L variants who lack such complex congenital heart malformations. Rather, they depict a syndromic form of ID characterized by facial dysmorphism, ID, speech impairment, motor developmental delay with muscular hypotonia and behavioral difficulties. We thereby define a novel syndrome and significantly broaden the clinical spectrum associated with MED13L variants. A prominent feature of the MED13L neurocognitive presentation is profound language impairment, often in combination with articulatory deficits.

  8. Redefining the MED13L syndrome

    Science.gov (United States)

    Adegbola, Abidemi; Musante, Luciana; Callewaert, Bert; Maciel, Patricia; Hu, Hao; Isidor, Bertrand; Picker-Minh, Sylvie; Le Caignec, Cedric; Delle Chiaie, Barbara; Vanakker, Olivier; Menten, Björn; Dheedene, Annelies; Bockaert, Nele; Roelens, Filip; Decaestecker, Karin; Silva, João; Soares, Gabriela; Lopes, Fátima; Najmabadi, Hossein; Kahrizi, Kimia; Cox, Gerald F; Angus, Steven P; Staropoli, John F; Fischer, Ute; Suckow, Vanessa; Bartsch, Oliver; Chess, Andrew; Ropers, Hans-Hilger; Wienker, Thomas F; Hübner, Christoph; Kaindl, Angela M; Kalscheuer, Vera M

    2015-01-01

    Congenital cardiac and neurodevelopmental deficits have been recently linked to the mediator complex subunit 13-like protein MED13L, a subunit of the CDK8-associated mediator complex that functions in transcriptional regulation through DNA-binding transcription factors and RNA polymerase II. Heterozygous MED13L variants cause transposition of the great arteries and intellectual disability (ID). Here, we report eight patients with predominantly novel MED13L variants who lack such complex congenital heart malformations. Rather, they depict a syndromic form of ID characterized by facial dysmorphism, ID, speech impairment, motor developmental delay with muscular hypotonia and behavioral difficulties. We thereby define a novel syndrome and significantly broaden the clinical spectrum associated with MED13L variants. A prominent feature of the MED13L neurocognitive presentation is profound language impairment, often in combination with articulatory deficits. PMID:25758992

  9. Impact of early detection and treatment of diabetes on the 6-year prevalence of cardiac autonomic neuropathy in people with screen-detected diabetes

    DEFF Research Database (Denmark)

    Charles, Morten; Fleischer, J; Witte, Daniel Rinse

    2013-01-01

    Baggrund: Der er begrænset viden om hvordan tidlig multifaktoriel behandling forbedrer konsekvenser af diabetes. Kardiel autonom neuropati (KAN) hos personer med diabetes indikerer omfattende skade på det autonome nervesystem og er relateret til mortalitet og livskvalitet. I dette studie fra...... ADDITION Danmark undersøgte vi effekten af tidlig opsporing og efterfølgende intensive behandling af type 2 diabetes i almen praksis på hyppigheden af kardiel autonom neuropati 6 år efter diagnose. Resultater: Prævalensen af tidlig KAN var 15,1% i rutine behandlingsgruppen (RG) og 15.5% i intensive...... kardiovaskulære risikofaktorer er således ikke nok til at forebygge at mange diabetes patienter udvikler KAN....

  10. Relevansen af nyere psykodynamisk teori for det klinisk musikterapeutiske arbejde med psykiatriske patienter med personlighedsforstyrrelser

    DEFF Research Database (Denmark)

    Hannibal, Niels

    2007-01-01

    Denne artikel beskriver et rationale for anvendelse af musik i en psykoterapeutisk kontekst. Det eksplicitte og implicitte forandringsniveau i psykoterapi med patienter med borderline-personlighedsforstyrrelse (BPF) diskuteres herpå med henvisning til to forskellige syn på terapeutisk forandring:...

  11. Ukraine i fokus sammen med Georgien

    DEFF Research Database (Denmark)

    Fledelius, Karsten

    2017-01-01

    Der er god grund til at sammenligne Ukraine og Georgien, nu fokuslande for Danmark, og der er god grund til at støtte disse to eks-sovjetiske stater med i høj grad parallelle problemer.......Der er god grund til at sammenligne Ukraine og Georgien, nu fokuslande for Danmark, og der er god grund til at støtte disse to eks-sovjetiske stater med i høj grad parallelle problemer....

  12. Ud med Freud, Marx og Lacan

    DEFF Research Database (Denmark)

    Clasen, Mathias

    2009-01-01

    Det er på høje tid, at humanister løsriver sig fra deres forældede teorier. Freud, Marx og Lacan skal erstattes med evolutionspsykologi, biologi og kognitionsvidenskab.......Det er på høje tid, at humanister løsriver sig fra deres forældede teorier. Freud, Marx og Lacan skal erstattes med evolutionspsykologi, biologi og kognitionsvidenskab....

  13. Effektelektronik - teknologi med energibesparelser og forbedret performance

    DEFF Research Database (Denmark)

    Blaabjerg, Frede

    2004-01-01

    Lige siden transistoren blev opfundet, har det altid været ønskeligt at kunne anvende en sådan til at styre store strømme/spændinger i elektriske systemer. Det er teknologisk også sket, først med tyristorer til styring af store effekter, men siden hen også med den bipolare transistor MOSFET, samt...

  14. Rutsjende dug - breddeopgave 73 med didaktisk kommentar

    DEFF Research Database (Denmark)

    Jensen, Jens Højgaard

    2017-01-01

    Mit formål med artikelserien om breddeopgaver er - udover at gøre opmærksom på RUCs fysikuddannelse - dobbelt: Dels udvælger jeg opgaverne, så de kan have interesse som fysikproblemer i egen ret. Dels udvælger jeg dem med henblik på at kunne knytte didaktiske overvejelser til dem af interesse for...

  15. Sociale indsatser til mennesker med ADHD

    DEFF Research Database (Denmark)

    Bengtsson, Steen; Alim, Winnie; Holmskov, Henriette

    Igennem de seneste år har flere og flere fået stillet diagnosen ADHD, som er en adfærdsmæssig forstyrrelse. Mennesker med ADHD har meget forskelligt støttebehov, og rapportens formål er at skabe overblik over de eksisterende sociale indsatser og tilbud til børn, unge og voksne med ADHD. Langt de...... ansvar for sociale end for terapeutiske tilbud i forhold til gruppen med ADHD. Mange voksne med ADHD beskriver, at det kræver mange ressourcer at få den fornødne støtte fra kommunen, mens forældre til børn med ADHD oplever det som nemmere at få adgang til de rette støttetilbud. Men begge grupper møder...... mange udfordringer som fx manglende koordinering og hyppige sagsbehandlerskift. Rapporten er udarbejdet i tilknytning til Servicestyrelsens projekt ’Ny og forstærket indsats til børn, unge og voksne med ADHD’ og er finansieret af Socialministeriet....

  16. Børsretlig praksis

    DEFF Research Database (Denmark)

    Schaumburg-Müller, Peer; Werlauff, Erik

    2008-01-01

    Artiklen gennemgår og kommenterer - i fortsættelse af forfatternes artikler i UfR 1994 B s. 295 ff, UfR 1995 B s. 211 ff, UfR 1996 B s. 119 ff, UfR 1997 B s. 182 ff, UfR 1998 B s. 189 ff, UfR 1999 B s. 146 ff, UfR 2000 B s. 234 ff, UfR 2001 B s. 110 ff, UfR 2002 B s. 147 ff, UfR 2003 B s. 111 ff,...

  17. Børsretlig praksis

    DEFF Research Database (Denmark)

    Werlauff, Erik; Schaumburg-Müller, Peer

    2009-01-01

    Artiklen gennemgår og kommenterer - i fortsættelse af forfatternes artikler i UfR 1994 B s. 295 ff, UfR 1995 B s. 211 ff, UfR 1996 B s. 119 ff, UfR 1997 B s. 182 ff, UfR 1998 B s. 189 ff, UfR 1999 B s. 146 ff, UfR 2000 B s. 234 ff, UfR 2001 B s. 110 ff, UfR 2002 B s. 147 ff, UfR 2003 B s. 111 ff,...

  18. Komunikasi dan Praksis Kebebasan

    OpenAIRE

    Teguh Ratmanto

    2000-01-01

    His paper concerns with communication and praxis of freedom. Communication in wider perspective is not just transftring a message but more than that. It is not just a process but involves many aspects of human lift such as culture and language. Culture and language reflect an understanding of reality. We can only perceive reality through language,whilelanguage can not be separated from culture. Language, basicly, is symbolization of reality using meaningful sign. That symbolization reducts re...

  19. Ledelsesfilosofi og Praksis

    DEFF Research Database (Denmark)

    Hertel, Frederik; Fast, Michael

    2015-01-01

    , som f.eks. Machiavellis ”Fyrsten”, Platons ”Statsmanden”, Taylors ”The Principles of Scientific Management” og Fayols ”General and Industrial Management”, har ledelse og ledelsesforskningen således koncentreret sig om ledelsestyper, god/rigtig ledelse, management/organisering og arbejdsdeling...

  20. Komunikasi dan Praksis Kebebasan

    Directory of Open Access Journals (Sweden)

    Teguh Ratmanto

    2000-12-01

    Full Text Available His paper concerns with communication and praxis of freedom. Communication in wider perspective is not just transftring a message but more than that. It is not just a process but involves many aspects of human lift such as culture and language. Culture and language reflect an understanding of reality. We can only perceive reality through language,whilelanguage can not be separated from culture. Language, basicly, is symbolization of reality using meaningful sign. That symbolization reducts reality into single aspect perceived by signs, however they want to represent it in one-ta-one correspondence. So the reality we perceive through language is not the real reality. It means that the communication we do is a complex action. The process of establishing meaning has something to do with people, because sign (language . by itself has no meaning. Words do not mean but people mean. In relating with power, the meaning ofsign (languange is determined by who holds the power. Whoever they are, they will have a dominant interpretation of meaning. Communication (as far as relate to culture, language, reality, and signis no longer free because it is not reflecting reality anymore, but symbolizing the power. Communication. naturally, is reflecting reality, that what we call free communication. But the(politicalpower has canged communication being just a tool for their interest. Communication reflects reducted reality. That is a chained communication. Communication has to be placed again in its natural place (reflecting reality sowe can interpretate reality freely.

  1. Forandringsledelse som responsiv praksis

    DEFF Research Database (Denmark)

    Molly, Asbjørn; Christensen, Tanja

    2014-01-01

    I artiklen gives et bud på ledelsens rolle i organisatorisk forandringsproces, baseret på en konkret organisatorisk forandringsproces, læst fra to forskellige teoretiske perspektiver. Dels John Kotters velkendte forandringsmodel, dels Ralph Staceys teori om complex responsive processes – en tilga...

  2. Utopi i praksis

    DEFF Research Database (Denmark)

    Berliner, Peter; De Casas, Elena; Christensen, Jeppe Høj

    2014-01-01

    Artiklen fremlægger en analyse af læring i et fredspsykologisk undervisningsforløb i Mexico som en del af opbygning af demokratiske og social resiliente læringsmiljøer fra børnehave til universitet.......Artiklen fremlægger en analyse af læring i et fredspsykologisk undervisningsforløb i Mexico som en del af opbygning af demokratiske og social resiliente læringsmiljøer fra børnehave til universitet....

  3. Parametri i praksis

    DEFF Research Database (Denmark)

    Banke, Tore

    2013-01-01

    of Fine Arts, School of Architecture, Design and Conservation. The project investigates how daylight quality, solar radiation control, and visual and thermal control can be design pa¬rameters in the initial design phase. The research is based on practical experiments performed in the competition...

  4. Strategi i praksis

    DEFF Research Database (Denmark)

    Holm, Michael Jessen; Jenster, Per; Junghagen, Sven

    Præsentation af seks danske små og mellemstore virksomheder, som alle har været succesfulde inden for deres metier. Gennem en belysning af hver virksomheds strategiske situation og udviklingsinitiativer skabes et billede af hvorledes strategi praktiseres i disse virksomheder......Præsentation af seks danske små og mellemstore virksomheder, som alle har været succesfulde inden for deres metier. Gennem en belysning af hver virksomheds strategiske situation og udviklingsinitiativer skabes et billede af hvorledes strategi praktiseres i disse virksomheder...

  5. Programmering i praksis

    DEFF Research Database (Denmark)

    Christensen*, Eva Petropouleas; Erkmann, Malene

    ved at bakke ind i. Data bliver konstant samlet ind om os og behandlet af algoritmer, der sender informationer videre til vores telefon, vores bil eller ud på nettet. Den, der kender koderne, har derfor adgang til flere informationer om os, end vi selv har overblik over. Der er mange grunde til...

  6. Implementering af evidensbaseret praksis

    DEFF Research Database (Denmark)

    Scheel, Linda Schumann; Tewes, Marianne; Petersen, Preben Ulrich

    2015-01-01

    Projektet omhandler implementering af den kliniske retningslinje om identifikation, forebyggelse og behandling af delirium – i denne sammenhæng relateret til hjertepatienter. Projektet foregår på to hospitaler i Hjertecentret på Rigshospitalet, et intensivt afsnit og et sengeafsnit, i tæt...

  7. Implementering af evidensbaseret praksis

    DEFF Research Database (Denmark)

    Scheel, Linda Schumann; Hansen, Ida Rode

    2014-01-01

    Projektet omhandler implementering af den kliniske retningslinje om identifikation, forebyggelse og behandling af delirium – i denne sammenhæng relateret til hjertepatienter. Projektet foregår på to hospitaler i Hjertecentret på Rigshospitalet, et intensivt afsnit og et sengeafsnit, i tæt...

  8. Akkreditering og klinisk praksis

    DEFF Research Database (Denmark)

    Hatting, Anne

    There is a growing awareness of a gap between the worlds of theory and practice within the field of organizational thinking, particularly when it comes to organizational change. Scholars are looking for methods to study practice and practitioners are looking for theories reflecting the real world...... and quality. This dissertation addresses quality improvement and organizational change, generally considered to be inseparable. In spite of strong efforts to produce guidelines for change projects, strategies and plans are often said to fail.But is there such a thing as a failing project? I find that this way...... of thinking about ʹfailing to fullfill plansʹ reflects a modern approach to research, a conception of the world as real and thruth as something objective, i.e. a rationalistic mode of thinking about relations between subjects and objects, stimulus and response. With a pragmatistic, interactionistic approach...

  9. Social indsats til borgere med erfaring fra salg af sex

    DEFF Research Database (Denmark)

    Mehlsen, Line; Amilon, Anna; Henriksen, Theresa Dyrvig

    2017-01-01

    Formålet med denne guide er at give endnu flere kommuner inspiration og vejledning til, hvordan man kan implementere og arbejde med CTI-forløb over for borgere med prostitutionserfaring. Manglende viden om borgere med prostitutionserfaringer gør det svært for kommunerne at hjælpe borgerne med de ...

  10. Human melioidosis reported by ProMED.

    Science.gov (United States)

    Nasner-Posso, Katherinn Melissa; Cruz-Calderón, Stefania; Montúfar-Andrade, Franco E; Dance, David A B; Rodriguez-Morales, Alfonso J

    2015-06-01

    There are limited sources describing the global burden of emerging diseases. A review of human melioidosis reported by ProMED was performed and the reliability of the data retrieved assessed in comparison to published reports. The effectiveness of ProMED was evaluated as a source of epidemiological data by focusing on melioidosis. Using the keyword 'melioidosis' in the ProMED search engine, all of the information from the reports and collected data was reviewed using a structured form, including the year, country, gender, occupation, number of infected individuals, and number of fatal cases. One hundred and twenty-four entries reported between January 1995 and October 2014 were identified. A total of 4630 cases were reported, with death reported in 505 cases, suggesting a misleadingly low overall case fatality rate (CFR) of 11%. Of 20 cases for which the gender was reported, 12 (60%) were male. Most of the cases were reported from Australia, Thailand, Singapore, Vietnam, and Malaysia, with sporadic reports from other countries. Internet-based reporting systems such as ProMED are useful to gather information and synthesize knowledge on emerging infections. Although certain areas need to be improved, ProMED provided good information about melioidosis. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  11. A marvel of precision: MedAustron

    CERN Document Server

    Anaïs Schaeffer

    2013-01-01

    MedAustron, which is currently being built in Austria, will be one of the most advanced centres for ion beam therapy and research in Europe. It is based on the same design as the Italian National Centre for Oncological Hadrontherapy (CNAO), which in turn is based on the CERN-led Proton Ion Medical Machine Study (PIMMS). MedAustron should welcome its first patient at the end of 2015.   Layout of the MedAustron accelerator complex.  With three ion-sources, a linac, a synchrotron and four irradiation rooms (see picture), MedAustron is a huge accelerator complex. Among other equipment, it comprises 300 magnets of 30 different types, all designed at CERN but produced at different sites: “We are working with five main suppliers from Europe and Russia,” explains Thomas Zickler, leader of the MedAustron magnet group. “All the magnets come to CERN to undergo a series of strict acceptance tests.” From the interfaces, to the electrical insulation, the co...

  12. Juridiske overvejelser i forbindelse med Influence Operationer

    DEFF Research Database (Denmark)

    Nissen, Thomas Elkjer

    2014-01-01

    Kapitel 8: Juridiske overvejelser i forbindelse med influence-operationer Af Thomas Elkjer Nissen Dette kapitel fokuserer ligesom kapitel 9 på de juridiske problemstillinger, som den teknologiske udvikling har bragt med sig til væbnede konflikter; i dette kapitel er der fokus på kommunikation....... Kapitlet ser nærmere på det moderne informationsmiljø, dets betydning i moderne konflikter og den stigende anvendelse af information som magtmiddel. Herefter rettes blikket mod de juridiske overvejelser, der er forbundet med influence-operationer, bl.a. tid og rum, chefansvar, mandat og juridisk grundlag....... Afsnittet behandler desuden bl.a. jus in bello’s grundlæggende princippers indflydelse på influence-operationer....

  13. Predicting clicks of PubMed articles.

    Science.gov (United States)

    Mao, Yuqing; Lu, Zhiyong

    2013-01-01

    Predicting the popularity or access usage of an article has the potential to improve the quality of PubMed searches. We can model the click trend of each article as its access changes over time by mining the PubMed query logs, which contain the previous access history for all articles. In this article, we examine the access patterns produced by PubMed users in two years (July 2009 to July 2011). We explore the time series of accesses for each article in the query logs, model the trends with regression approaches, and subsequently use the models for prediction. We show that the click trends of PubMed articles are best fitted with a log-normal regression model. This model allows the number of accesses an article receives and the time since it first becomes available in PubMed to be related via quadratic and logistic functions, with the model parameters to be estimated via maximum likelihood. Our experiments predicting the number of accesses for an article based on its past usage demonstrate that the mean absolute error and mean absolute percentage error of our model are 4.0% and 8.1% lower than the power-law regression model, respectively. The log-normal distribution is also shown to perform significantly better than a previous prediction method based on a human memory theory in cognitive science. This work warrants further investigation on the utility of such a log-normal regression approach towards improving information access in PubMed.

  14. Online lektiehjælp – Udvikling af en vejledningsdidaktik med pædagogisk designforskning som metode

    Directory of Open Access Journals (Sweden)

    Jens Jørgen Hansen

    2016-05-01

    Full Text Available Lektievejledning er en pædagogisk praksis i rivende udvikling med fokus på at støtte elever i at forstå og håndtere udfordringer i deres lektiearbejde. Lektievejledning er på den politiske dagsorden i skole og ungdomsuddannelser og tilbydes både internt af uddannelsesinstitutionerne samt af private og offentlige aktører. Men lektievejledning er ikke etableret som et teoretisk felt eller som en særlig vejledningskompetence. Der er således behov for at begrebsliggøre og udvikle teori om, hvad lektievejledning er, og hvordan vejledningsformen didaktisk kan håndteres. Mere konkret er ud-fordringen at udvikle et nuanceret fagsprog samt en modellering af feltet til forklaring af lektievejledningens komplekse praksis med det mål at udvikle og kvalificere lektievejledning som pædagogisk teori og pædagogisk prak-sis. Denne artikel præsenterer resultatet af et forskningsprojekt, hvis mål er at udvikle en vejledningsdidaktik, herunder metoder, modeller og materialer for lektievejledning i regi af Lektier Online. Lektier Online er en organisation ved Statsbiblioteket i Århus, der tilbyder en online lektiecafe, hvor bl.a. gymnasie-elever kan få hjælp af frivillige universitetsstuderende. Dette didaktiske de-sign er et eksempel på, hvordan digitalisering og ny teknologi er en katalysator for udvikling af nye innovative læringsmiljøer og læringstilbud, der åbner fleksible og stedsuafhængige rum for læring, giver mulighed for samspil med aktører uden for skolens formelle rammer, og som er båret af integration af digitale teknologier i læringssituationen. Artiklen beskriver forskningsproces-sen med at indkredse en vejledningsdidaktik for lektiehjælp samt udviklingen, konceptualiseringen, afprøvningen og evalueringen af en række vejlednings-modeller på grundlag af forskningsmetoden Pædagogisk designforskning og dens tradition for brugerdreven innovation. Artiklen beskriver for det første resultatet af forskningsprocessen i form

  15. Ti år med formidlingspligt

    DEFF Research Database (Denmark)

    Meyer, Gitte

    2014-01-01

    Jubilæet blev markeret ved et symposium - men hvor var journalisterne, og hvor var forskerne? For få uger siden lagde TV 2 hus til et symposium om videnskab, formidling, journalistik og spin. Danske Videnskabsjournalister og Akademiet for de Tekniske Videnskaber tog med arrangementet et behjertet...... initiativ. De ville gøre status efter ti år med lovfæstet formidlingspligt på universiteterne. Samtidig lagde de op til et kritisk blik på universitetsverdenens kommunikationsafdelinger...

  16. Hvad SKER der med drikkevandet i USA?

    DEFF Research Database (Denmark)

    Ramsay, Loren Mark

    2017-01-01

    Forskellige lande har forskellige traditioner indenfor drikkevandsbehandling. Denne beretning fra ”Water Quality Technology Conference” i USA er set med en særlig vinkel, da forfatteren er amerikansk statsborger, men har arbejdet i den danske vandbranche i mere end 25 år.......Forskellige lande har forskellige traditioner indenfor drikkevandsbehandling. Denne beretning fra ”Water Quality Technology Conference” i USA er set med en særlig vinkel, da forfatteren er amerikansk statsborger, men har arbejdet i den danske vandbranche i mere end 25 år....

  17. Akupunktur til patienten med kvalme og opkastning i forbindelse med kemoterapi - er der evidens for dette?

    DEFF Research Database (Denmark)

    Pedersen, Birgith; Sørensen, Lene Bundgaard; Stricker, Lisbeth

    2008-01-01

      Patienter, der får kemoterapi med højemetogene stoffer lider stadig af kvalme og opkastning trods understøttende behandling med moderne antieemtika som 5HT3-antagonister eksempelvis ondansetron. Akupunkturstimulation anvendes for flere lidelser i sundhedsvæsenet og det undersøges om der er evid...

  18. PubMedReco: A Real-Time Recommender System for PubMed Citations.

    Science.gov (United States)

    Samuel, Hamman W; Zaïane, Osmar R

    2017-01-01

    We present a recommender system, PubMedReco, for real-time suggestions of medical articles from PubMed, a database of over 23 million medical citations. PubMedReco can recommend medical article citations while users are conversing in a synchronous communication environment such as a chat room. Normally, users would have to leave their chat interface to open a new web browser window, and formulate an appropriate search query to retrieve relevant results. PubMedReco automatically generates the search query and shows relevant citations within the same integrated user interface. PubMedReco analyzes relevant keywords associated with the conversation and uses them to search for relevant citations using the PubMed E-utilities programming interface. Our contributions include improvements to the user experience for searching PubMed from within health forums and chat rooms, and a machine learning model for identifying relevant keywords. We demonstrate the feasibility of PubMedReco using BMJ's Doc2Doc forum discussions.

  19. Ecological urban renewal in Vesterbro, Copenhagen - 3 buildings with low-energy and solar energy in practice[Denmark]; Byoekologisk byfornyelse paa Vesterbro - 3 ejendomme med lavenergi- og solenergianvendelse i praksis

    Energy Technology Data Exchange (ETDEWEB)

    Vejsig Pedersen, P.

    2000-03-01

    The report is the final report on a demonstration project backed by the Danish Energy Agency concerning solar energy/low energy solutions in relation to ecological urban renewal in Hedebygade, Vesterbro. The report describes developing work relating to solar cells, ventilation with counter current heat recover and total economic and ecological urban optimization, and innovating initiatives relating to 3 buildings with a total of 62 apartments and a business property. The annual energy consumption for heating and hot water can be reduced by a combination of the following means: Use of super low-energy windows; New ventilation solutions with counter current heat recovery and air heating; Use of facade insulation, solar walls and building integrated solar cells; New types of low temperature installations e.g. centrally placed radiators and use of hot water heat exchangers; Improved light conditions by use of glassed rooms. (EHS)

  20. Historien med stort H endte i '89

    DEFF Research Database (Denmark)

    Østergaard, Uffe

    2015-01-01

    Revolution. Uffe Østergaard, Jean Monnet professor i europæisk historie på Copenhagen Business School, tager os med op, og betragter debatten om årsagerne til, og betydningen af, Murens fald i fugleperspektiv. Hvorfor var der ingen, der havde forudset begivenhederne?...

  1. Professor Nukem - et eksperiment med oplevelsesbaseret forskningsformidling

    DEFF Research Database (Denmark)

    Sandvik, Kjetil; Thorhauge, Anne Mette

    2007-01-01

    Professor Nukem er resultatet af et forskningsprojekt om oplevelsesbaseret forskningsformidling der har form som et computerspil med tilhørende website, hvor brugeren interaktivt kan engagere sig i forskning omkring sociale og kulturelle aspekter ved computerspil. Professor Nukem kan spilles på...

  2. Hvad stiller vi op med samfundsneurosen?

    DEFF Research Database (Denmark)

    Jensen, Niels Rosendal

    2008-01-01

    Pædagogisk og socialt arbejde er som aldrig før udsat for evaluering, accountability, akkreditering m.v.  Det fjerner opmærksomheden fra kerneopgaven, at de professionelles ydelser forbedres. Forhistorien opridses kort, og klummen afrundes med at pege på tre mulige veje ud af samfundsneurosen: et...

  3. MED-SUV Data Life Cycle

    Science.gov (United States)

    Sangianantoni, Agata; Puglisi, Giuseppe; Spampinato, Letizia; Tulino, Sabrina

    2015-04-01

    The MED-SUV project aims to implement a digital e-infrastructure for data access in order to promote the monitoring and study of key volcanic regions prone to volcanic hazards, and thus improve hazard assessment, according to the rationale of Supersite GEO initiative to Vesuvius- Campi Flegrei and Mt Etna, currently identified as Permanent Supersites. The present study focuses on the life cycle of MED-SUV data generated in the first period of the project and highlights the managing approach, as well as the crucial steps to be implemented for ensuring that data will be properly and ethically managed and can be used and accessed from both MED-SUV and the external community. The process is conceived outlining how research data being handled as the project progresses, describing what data are collected, processed or generated and how these data are going to be shared and made available through Open Access. Data cycle begins with their generation and ends with the deposit in the digital infrastructure, its key series of stages through which MED-SUV data passes are Collection, Data citation, Categorization of data, Approval procedure, Registration of datasets, Application of licensing models, and PID assignment. This involves a combination of procedures and practices taking into account the scientific core mission and the priorities of the project as well as the potential legal issues related to the management and protection of the Intellectual Property. We believe that the implementation of this process constitutes a significant encouragement in MED-SUV data sharing and as a consequence a better understanding on the volcanic processes, hazard assessment and a better integration with other Supersites projects.

  4. Musikterapi med børn med svær autisme - en litteraturgennemgang

    Directory of Open Access Journals (Sweden)

    Ulla Holck

    2003-03-01

    Full Text Available Faglitteratur om musikterapi med børn med autisme er omfattende og indeholder såvel kvalitative case-beskrivelser som kvantitative forskningsundersøgelser. I artiklen gennemgås faglitteraturen systematisk med henblik på at specifi cere musikterapiens effekt og virkemåder i forhold til denne målgruppe. Vægten ligger på børn med svær autisme, men litteratur om voksne højtfungerende personer med autisme inddrages også. Forskningslitteraturen viser, at det især er inden for områderne koncentration, visuel opmærksomhed, respons og initiativ, samt brug af stemme og tur-tagning, at musikterapi har en effekt. Case-litteraturen begrunder denne effekt med musikkens evne til at være redundant, anvendelse af imitation og responsfremmende teknikker (overraskelse etc., fælles opbyggede samspilsformer, samt det temporale-interaktive element i improvisatorisk musikterapi. Ud fra en interaktionsteoretisk indfaldsvinkel sammenkobles effekten endvidere med, at den musikalske interaktion hjælper musikterapeuten til at fastholde et dynamisk udtryk, hvilket er afgørende i forhold til en klientgruppe, der ofte giver ´flad´ eller stærkt afvigende feedback.

  5. Psychological and social problems in primary care patients - general practitioners' assessment and classification

    DEFF Research Database (Denmark)

    Rosendal, Marianne; Vedsted, Peter; Christensen, Kaj Sparle

    2013-01-01

    I almen praksis får 11 % af patienterne en diagnose, der vedrører psykisk sygdom. Heraf har halvdelen en depression eller en belastningstilstand. Kun 18 af de 43 tilgængelige diagnoser i ICPC anvendes regelmæssigt. Sociale problemer angives sjældent som primær problemstilling (0,5 %). Uafhængigt ...

  6. A geographical cluster randomised stepped wedge study of continuing medical education and cancer diagnosis in general practice

    DEFF Research Database (Denmark)

    Toftegaard, Berit; Bro, Flemming; Vedsted, Peter

    2014-01-01

    Alment praktiserende læger spiller en nøglerolle for tidlig diagnostik af kræft. Denne artikel beskriver en intervention i form af efteruddannelse af alment praktiserende læger i tidlig diagnostik af kræft. Artiklen beskriver identifikation af barrierer i almen praksis for tidlig diagnostik af...

  7. Opće i posebno ograničenje odgovornosti za pomorske tražbine u novijoj stranoj sudskoj praksi

    Directory of Open Access Journals (Sweden)

    Jasenko Marin

    2011-12-01

    Full Text Available Tema rada je proučavanje tumačenja i primjene međunarodnih propisa o općem i posebnom ograničenju odgovornosti za pomorske tražbine u novijoj sudskoj praksi. U uvodnom dijelu objašnjava se gospodarska i pravna svrha instituta ograničenja odgovornosti te se daje prikaz njegova uređenja na međunarodnoj razini. Naglašava se njegova ključna uloga u razvitku brodarstva i međunarodne trgovine. Kritički se analiziraju novije ilustrativne odluke stranih sudova u kojima su protumačene i primijenjene nerijetko dvojbene odredbe međunarodnih ugovora kojima je uređena ova materija. Iznose se zaključci o trenutnoj kvaliteti pravnog uređenja toga instituta, uočavaju tendencije njegova budućeg razvitka te predlažu mjere potrebne za njegovu daljnju nadogradnju.

  8. Hvad skal vi med Trump-satire?

    DEFF Research Database (Denmark)

    Møller, Mette

    2017-01-01

    Trump-satire er et stort hit, og særligt en lang række satiriske videohilsner til Trump fra lande verden over får folk til at trække på smilebåndet. Men hvorfor er det så sjovt at gøre grin med Trump, og hvad kan vi bruge den politiske humor til?......Trump-satire er et stort hit, og særligt en lang række satiriske videohilsner til Trump fra lande verden over får folk til at trække på smilebåndet. Men hvorfor er det så sjovt at gøre grin med Trump, og hvad kan vi bruge den politiske humor til?...

  9. Analys av nickel med ICP-MS

    OpenAIRE

    Wallman, Karin; Löfgren, Stefan; Sonesten, Lars; Demandt, Christian

    2009-01-01

    Vid en granskning av nickelhalter för perioden 1985-2007 upptäcktes ett nivåskifte i tidsserierna på flera stationer mellan 2001 och 2002. Skiftet visade sig bero på att prover innan 2002 inte korrigerades för kalciuminterferens, medan prover under åren 2002-2007 korrigerades. Syftet med denna rapport är att utreda om resultaten före 2002 i efterhand kan korrigeras för kalciuminterferensen. Från 2002 finns ett antal prover (N=347) med resultat som både är kalciumkorrigerade och som inte är de...

  10. Poetisk sortsyn med lys for enden

    DEFF Research Database (Denmark)

    Larsen, Peter Stein

    2015-01-01

    Ursula Andkjær Olsens digtsamling " Udgående fartøj" indledes med den følgende prægnante passage, der kan læses i sin helhed som " ugens digt" her på siden: " jeg har brugt tid på at tyde/ sprede dumpe fornemmelser / fra mit fjerne indre (...)......Ursula Andkjær Olsens digtsamling " Udgående fartøj" indledes med den følgende prægnante passage, der kan læses i sin helhed som " ugens digt" her på siden: " jeg har brugt tid på at tyde/ sprede dumpe fornemmelser / fra mit fjerne indre (...)...

  11. Med sjefen på Facebook: En studie av ledere som er "venner" med sine ansatte

    OpenAIRE

    Jensen, Anita

    2014-01-01

    MR690 Masteroppgave i organisasjon og ledelse - utdanningsledelse Formålet med studien er å belyse hvordan aktiv bruk av sosiale medier, i dette tilfellet Facebook, påvirker relasjoner mellom mennesker. Hva skjer når en tar i bruk en websjanger som i utgangspunktet er umiddelbar og uformell, til jobbrelatert og mer formell kommunikasjon? Er det sjangeren eller relasjonen som endres? Søkelyset rettes mot ledere som er “venner” med sine medarbeidere, og problemstillingen er...

  12. Technical development of PubMed Interact: an improved interface for MEDLINE/PubMed searches

    OpenAIRE

    Muin, Michael; Fontelo, Paul

    2006-01-01

    Abstract Background The project aims to create an alternative search interface for MEDLINE/PubMed that may provide assistance to the novice user and added convenience to the advanced user. An earlier version of the project was the 'Slider Interface for MEDLINE/PubMed searches' (SLIM) which provided JavaScript slider bars to control search parameters. In this new version, recent developments in Web-based technologies were implemented. These changes may prove to be even more valuable in enhanci...

  13. Inklusion i folkeskolen med musik og musikterapi

    DEFF Research Database (Denmark)

    Lindvang, Charlotte

    2014-01-01

    I denne artikel sættes der fokus på nogle af de problemer og udfordringer som knytter sig til kravet om inklusion af børn med særlige behov i den almindelige folkeskole, og der argumenteres for at styrke anvendelsen af musik i forhold til at skabe fællesskab og optimere børnenes opmærksomhed og...

  14. Sydkorea: Teknologiske tigerspring med globale udfordringer

    DEFF Research Database (Denmark)

    Brynskov, Martin

    2010-01-01

    Sydkorea har gennemgået en utrolig udvikling fra u-land til førende i-land i løbet af få årtier. Helt centralt står den teknologiske eksport af elektronik, biler og skibsbyggeri i verdenseliten. Men på trods af de mange succeser er der også udfordringer. Denne analyse viser – med aktuelle eksempl...

  15. Digital kommunikation med den offentlige sektor

    DEFF Research Database (Denmark)

    Berger, Jesper Bull; Andersen, Kim Normann

    til. I denne undersøgelse sættes der fokus på myndighedernes besvarelse af den digitale post. Digital post blev bl.a. etableret som et alternativ til almindelig e-mail for at det offentlige kan kommunikere med borgere og virksomheder på en sikker måde, dvs. uden at uvedkommende kan få adgang til...... følsomme oplysninger. Fokus for undersøgelsen er hvordan håndterer myndighederne besvarelserne i den digitale postkasse: svarer de på digital post og e-mail, hvor hurtigt svarer de og er svarene brugbare? Undersøgelsen medtager myndighedernes besvarelse af digital post og e-mail, dels for at kunne...... sammenligne de to digitale kanaler og for at kunne sammenligne med en tidligere undersøgelse af digital kommunikation med det offentlige. Herudover er der tidligere gennemført en undersøgelse af e-mail svar og svartider i New Zealand og Australien. De danske resultater fra e-mail undersøgelsen, men ikke...

  16. Forandringslæring med autismediagnoser?

    DEFF Research Database (Denmark)

    Gustafson, Kari Ingrid; Mørck, Line Lerche

    2013-01-01

    Artiklen drøfter en række aktuelle spørgsmål omkring læring hos børn og unge med autisme-spektrum-forstyrrelses diagnoser. Der introduceres til en social praksisteoretisk forståelse af forandringslæring, der diskuterer forandring ikke kun i relation til en persons identitet, men også aktuelle og...... potentielle forandringer, når det gælder overskridelse af binær logik i autisme versus normalitet, samt i relation til at overskride individualiserede og dualistiske problem-forståelser af fejl og mangler ved det autistiske barn. Det illustreres, hvordan disse former for dualistisk tænkning er forankret i et...... Rasmus’ ændringer i læring, selvforståelse og tilhørsforhold perspektiveres med andre ASF-diagnostiseredes læring udforsket bl.a. gennem gruppeinterviews i regi af Asperger-foreningen. Artiklen byder således på et alternativ i form af at forstå forandringslæring som overskridende læring, med langt større...

  17. Evaluering af ordning med psykologbehandling af personer med let til moderat depression

    DEFF Research Database (Denmark)

    Fjeldsted, Rita; Christensen, Kaj Sparle

    Herværende rapport evaluerer den pr. 1.4.2008 indførte ordning med mulighed for henvisning til psykologbehandling med 60 % tilskud for patienter med let til moderat depression. Evalueringen har betjent sig af flere gensidigt supplerende metoder: spørgeskemaundersøgelser overfor patienter, psykolo......Herværende rapport evaluerer den pr. 1.4.2008 indførte ordning med mulighed for henvisning til psykologbehandling med 60 % tilskud for patienter med let til moderat depression. Evalueringen har betjent sig af flere gensidigt supplerende metoder: spørgeskemaundersøgelser overfor patienter...... tidligere evaluering af forsøgsordning af psykologbehandling af depression i perioden 2005-06. 18.419 personer i alderen 18-37 år blev henvist til psykolog i den undersøgte ordning i perioden 1.2.2009 – 31.1.2010, svarende til en henvisningshyppighed på 1,6 % af baggrundsbefolkningen i samme aldersgruppe....... Ordningen giver mulighed for én rehenvisning, og 9 % blev rehenvist i perioden. Spørgeskemaresultater viser, at kun 33 % af de henviste falder ind under henvisningskriteriet ” let til moderat depression” på tidspunktet for opstart af psykologbehandling, 39 % har ingen tegn på depression, og 28 % har svær...

  18. Lineær programmering med Excel

    DEFF Research Database (Denmark)

    Lynggaard, Peter

    Publikationen giver en introduktion til faget "Lineær programmering". Formulering og løsning bygger på, at modellerne opstilles og løses i et Excel-regneark. Fremgangsmåden er forklaret trin for trin, således at hæftet kan bruges som selvstudiemateriale. Indholdsfortegnelse Generelt om styring og...... planlægning Lineær programmering Excel solveren Fortolkning af udskrifter Degeneration Excel tips Opgaver med løsninger...

  19. Manifest for en psykiatri med brugerrespekt

    DEFF Research Database (Denmark)

    Samskabelsesprojekt med psykiatribrugere og pårørende. Psykiatri Manifestet består af forskellige statements om psykiatrien som den opleves set fra brugerperspektiv, og visioner om hvor brugerne ønsker, den skal udvikle sig hen. Brugerne har reageret på Marianne Træbing Sechers invitation via hen...... hendes kontoer på Facebook, Twitter og LinkedIn, samt gennem nedenstående facebooksider og interesseorganisationer. Marianne er ansat som adjunkt på VIA University College og står for videreuddannelse, konsulentarbejde og forskning/udvikling på psykiatriområdet i tilknytning hertil....

  20. PubMed-EX: a web browser extension to enhance PubMed search with text mining features.

    Science.gov (United States)

    Tsai, Richard Tzong-Han; Dai, Hong-Jie; Lai, Po-Ting; Huang, Chi-Hsin

    2009-11-15

    PubMed-EX is a browser extension that marks up PubMed search results with additional text-mining information. PubMed-EX's page mark-up, which includes section categorization and gene/disease and relation mark-up, can help researchers to quickly focus on key terms and provide additional information on them. All text processing is performed server-side, freeing up user resources. PubMed-EX is freely available at http://bws.iis.sinica.edu.tw/PubMed-EX and http://iisr.cse.yzu.edu.tw:8000/PubMed-EX/.

  1. Bygningsdele med celluloseuld og høruld

    DEFF Research Database (Denmark)

    Hansen, Ernst Jan de Place

    2001-01-01

    Resume af rapport med eksempler på bygningsdele med papir- eller hørisolering, der overholder bygningsreglementerne, udarbejdet af Dansk Brandteknisk Institut under Energistyrelsens udviklingsprogram "Miljø- og arbejdsmiljøvenlig isolering"...

  2. Ødelæg alt muligt med et bogstav

    DEFF Research Database (Denmark)

    Konzack, Lars

    2017-01-01

    En gang imellem griber en raptus SoMe-Danmark, og så fyldes alles feed med samme slags indhold. Senest overspringshandlede vi med hashtagget #oedelaeg1filmed1bogstav - og alle mulige afledninger af det....

  3. COSMO-SkyMed and GIS applications

    Science.gov (United States)

    Milillo, Pietro; Sole, Aurelia; Serio, Carmine

    2013-04-01

    Geographic Information Systems (GIS) and Remote Sensing have become key technology tools for the collection, storage and analysis of spatially referenced data. Industries that utilise these spatial technologies include agriculture, forestry, mining, market research as well as the environmental analysis . Synthetic Aperture Radar (SAR) is a coherent active sensor operating in the microwave band which exploits relative motion between antenna and target in order to obtain a finer spatial resolution in the flight direction exploiting the Doppler effect. SAR have wide applications in Remote Sensing such as cartography, surface deformation detection, forest cover mapping, urban planning, disasters monitoring , surveillance etc… The utilization of satellite remote sensing and GIS technology for this applications has proven to be a powerful and effective tool for environmental monitoring. Remote sensing techniques are often less costly and time-consuming for large geographic areas compared to conventional methods, moreover GIS technology provides a flexible environment for, analyzing and displaying digital data from various sources necessary for classification, change detection and database development. The aim of this work si to illustrate the potential of COSMO-SkyMed data and SAR applications in a GIS environment, in particular a demostration of the operational use of COSMO-SkyMed SAR data and GIS in real cases will be provided for what concern DEM validation, river basin estimation, flood mapping and landslide monitoring.

  4. Ion sources for MedAustron

    International Nuclear Information System (INIS)

    Lettry, J.; Penescu, L.; Wallner, J.; Sargsyan, E.

    2010-01-01

    The MedAustron Ion therapy center will be constructed in Wiener Neustadt (Austria) in the vicinity of Vienna. Its accelerator complex consists of four ion sources, a linear accelerator, a synchrotron, and a beam delivery system to the three medical treatment rooms and to the research irradiation room. The ion sources shall deliver beams of H 3 1+ , C 4+ , and light ions with utmost reliability and stability. This paper describes the features of the ion sources presently planned for the MedAustron facility, such as ion source main parameters, gas injection, temperature control, and cooling systems. A dedicated beam diagnostics technique is proposed in order to characterize electron cyclotron resonance (ECR) ion beams; in the first drift region after the ion source, a fraction of the mixed beam is selected via moveable aperture. With standard beam diagnostics, we then aim to produce position-dependant observables such as ion-current density, beam energy distribution, and emittance for each charge states to be compared to simulations of ECR e-heating, plasma simulation, beam formation, and transport.

  5. MedAustron board visits CERN

    CERN Multimedia

    CERN Bulletin

    On 14 October, the board of EBG MedAustron, which is overseeing the construction of Austria’s hadron therapy centre, visited CERN. The visit recognized the relationship of shared knowledge, technology and training between CERN and MedAustron.   Normal.dotm 0 0 1 17 98 cern 1 1 120 12.0 0 false 18 pt 18 pt 0 0 false false false /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0cm; line-height:115%; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin;} ...

  6. Ion Sources for MedAustron

    CERN Document Server

    Lettry, J; Wallner, J; Sargsyan, E; CERN. Geneva. BE Department

    2010-01-01

    The MedAustron Ion therapy center will be constructed in Wiener Neustadt (Austria) in the vicinity of Vienna. Its accelerator complex consists of four ion sources, a linear accelerator, a synchrotron and a beam delivery system to the three medical treatment rooms and to the research irradiation room. The ion sources shall deliver beams of H31+, C4+ and light ions with utmost reliability and stability. This paper describes the features of the ion sources presently planned for the MedAustron facility; such as ion source main parameters, gas injection, temperature control and cooling systems. A dedicated beam diagnostics technique is proposed in order to characterize ECR ions beams; in the first drift region after the ion source, a fraction of the mixed beam is selected via moveable aperture. With standard beam diagnostics, we then aim to produce position-dependant observables such as ion-current density, beam energy distribution and emittance for each charge states to be compared to simulations of ECR e-heating...

  7. Digital kommunikation med den offentlige sektor

    DEFF Research Database (Denmark)

    Berger, Jesper; Andersen, Kim Normann

    2013-01-01

    Denne rapport sammenfatter hovedresultaterne af en undersøgelse gennemført i juni måned 2013 om besvarelse af e-mail og digital post i den statslige, regionale og kommunale sektor. Allerede med eDag3 1. nov. 2010 skulle alle myndigheder have oprettet en digital postkasse, som borgerne kunne skrive...... til. I denne undersøgelse sættes der fokus på myndighedernes besvarelse af den digitale post. Digital post blev bl.a. etableret som et alternativ til almindelig e-mail for at det offentlige kan kommunikere med borgere og virksomheder på en sikker måde, dvs. uden at uvedkommende kan få adgang til...... følsomme oplysninger. Fokus for undersøgelsen er hvordan håndterer myndighederne besvarelserne i den digitale postkasse: svarer de på digital post og e-mail, hvor hurtigt svarer de og er svarene brugbare? Undersøgelsen medtager myndighedernes besvarelse af digital post og e-mail, dels for at kunne...

  8. Digital kommunikation med den offentlige sektor

    DEFF Research Database (Denmark)

    Berger, Jesper Bull; Andersen, Kim Normann

    Denne rapport sammenfatter hovedresultaterne for styrelser og statslige organisationer af en undersøgelse gennemført i sommeren 2013 om besvarelse af e-mail og digital post i den statslige, regionale og kommunale sektor. Allerede med eDag3 1. nov. 2010 skulle alle myndigheder have oprettet en...... digital postkasse, som borgerne kunne skrive til. I denne undersøgelse sættes der fokus på myndighedernes besvarelse af den digitale post. Digital post blev bl.a. etableret som et alternativ til almindelig e-mail for at det offentlige kan kommunikere med borgere og virksomheder på en sikker måde, dvs....... uden at uvedkommende kan få adgang til følsomme oplysninger. Fokus for undersøgelsen er hvordan håndterer myndighederne besvarelserne i den digitale postkasse: svarer de på digital post og e-mail, hvor hurtigt svarer de og er svarene brugbare? Vi har også undersøgt besvarelse af e-mail, dels...

  9. Development of an Intervention for implementing Immunochemical Faecal Occult Blood Test in General Practice

    DEFF Research Database (Denmark)

    Juul, Jakob Søgaard; Vedsted, Peter; Bro, Flemming

    2016-01-01

    Denne korte artikel handler om udviklingen af en intervention til implementering af immunochemical faecal occult blood test (iFOBT) i almen praksis. Artiklen gennemgår processen fra de tidlige udviklingsstadier, over pilot-testning og frem til de endelige justeringer før selve implementeringen blev...... vurdering og viden om patienten. Kombinationen af teori og praksis viste sig at være en god måde at sikre hurtig ibrugtagning af en ny test i almen praksis til at identificere potentielle tegn på tarmkræft hos patienter. Særligt pilot-testning af interventionen viste sig at være værdifuld, fordi den...

  10. The MEDIATOR genes MED12 and MED13 control Arabidopsis root system configuration influencing sugar and auxin responses.

    Science.gov (United States)

    Raya-González, Javier; López-Bucio, Jesús Salvador; Prado-Rodríguez, José Carlos; Ruiz-Herrera, León Francisco; Guevara-García, Ángel Arturo; López-Bucio, José

    2017-09-01

    Arabidopsis med12 and med13 mutants exhibit shoot and root phenotypes related to an altered auxin homeostasis. Sucrose supplementation reactivates both cell division and elongation in primary roots as well as auxin-responsive and stem cell niche gene expression in these mutants. An analysis of primary root growth of WT, med12, aux1-7 and med12 aux1 single and double mutants in response to sucrose and/or N-1-naphthylphthalamic acid (NPA) placed MED12 upstream of auxin transport for the sugar modulation of root growth. The MEDIATOR (MED) complex plays diverse functions in plant development, hormone signaling and biotic and abiotic stress tolerance through coordination of transcription. Here, we performed genetic, developmental, molecular and pharmacological analyses to characterize the role of MED12 and MED13 on the configuration of root architecture and its relationship with auxin and sugar responses. Arabidopsis med12 and med13 single mutants exhibit shoot and root phenotypes consistent with altered auxin homeostasis including altered primary root growth, lateral root development, and root hair elongation. MED12 and MED13 were required for activation of cell division and elongation in primary roots, as well as auxin-responsive and stem cell niche gene expression. Remarkably, most of these mutant phenotypes were rescued by supplying sucrose to the growth medium. The growth response of primary roots of WT, med12, aux1-7 and med12 aux1 single and double mutants to sucrose and application of auxin transport inhibitor N-1-naphthylphthalamic acid (NPA) revealed the correlation of med12 phenotype with the activity of the auxin intake permease and suggests that MED12 acts upstream of AUX1 in the root growth response to sugar. These data provide compelling evidence that MEDIATOR links sugar sensing to auxin transport and distribution during root morphogenesis.

  11. Tur-samspil i musikterapi med børn med svære kommunikationsvanskeligheder

    DEFF Research Database (Denmark)

    Holck, Ulla

    2006-01-01

    Tur-samspil udgør en vigtig grundsten i den tidlige sociale og kommunikative udvikling, og optræder ofte i musikterapeutiske samspil med kommunikationssvage børn. Artiklen præsenterer relevante begreber fra faglitteraturen om tur-samspil i voksendialoger (de såkaldte Konversationsanalyser), som k...

  12. Praktische handleiding PubMed : hét boek om snel en doeltreffend te zoeken in PubMed

    NARCIS (Netherlands)

    Etten-Jamaludin, van F.; Deurenberg, H.W.J.

    2010-01-01

    Praktische handleidng PubMed is de eerste Nederlandstalige gids die op overzichtelijke wijze op de uitgebreide mogelijkheden van PubMed ingaat. PubMed (www.pubmed.gov) biedt gratis toegang tot MEDLINE en is de meest gebruikte medische zoekmachine. In deze geheel herziene derde editie van Praktisch

  13. Psychological distress, cardiovascular complications and mortality among people with screen-detected type 2 diabetes

    DEFF Research Database (Denmark)

    Dalsgaard, Else-Marie; Vestergaard, Mogens; Skriver, Mette V

    2014-01-01

    Dette studie undersøger, om psykisk belastning øger risikoen for kardiovaskulær sygdom og død blandt personer med type 2-diabetes. Forfatterne ser også nærmere på, om forskelle i metabolisk kontrol og indtag af ordineret medicin kan forklare dele af en eventuel sammenhæng. Studiet fandt, at 18% af...... personer fundet med type 2-diabetes ved screening led af psykisk belastning. Studiet viser, at psykisk belastede personer har 70% højere risiko for at få CVD-event i 8.7 års follow-up og 80% højere dødelighed i 10.9 års follow-up sammenlignet med personer med type 2-diabetes uden psykisk belastning....... Psykisk belastning synes derimod ikke generelt at påvirke evnen til at opnå de opsatte mål for HbA1c, kolesterol og blodtryk. Studiet, bygger på data fra 1533 personer i alderen 40-69 år, som fik konstateret type 2-diabetes ved screening i almen praksis, 2001-2006. Undersøgelsen udgør en del af ADDITION...

  14. Redox regulation of the MED28 and MED32 mediator subunits is important for development and senescence.

    Science.gov (United States)

    Shaikhali, Jehad; Davoine, Céline; Björklund, Stefan; Wingsle, Gunnar

    2016-05-01

    Mediator is a conserved multi-protein complex that acts as a bridge between promoter-bound transcriptional regulators and RNA polymerase II. While redox signaling is important in adjusting plant metabolism and development, the involvement of Mediator in redox homeostasis and regulation only recently started to emerge. Our previous results show that the MED10a, MED28, and MED32 Mediator subunits form various types of covalent oligomers linked by intermolecular disulfide bonds in vitro. To link that with biological significance we have characterized Arabidopsis med32 and med28 mutants and found that they are affected in root development and senescence, phenotypes possibly associated to redox changes.

  15. Analysis of PubMed User Sessions Using a Full-Day PubMed Query Log: A Comparison of Experienced and Nonexperienced PubMed Users

    Science.gov (United States)

    2015-01-01

    Background PubMed is the largest biomedical bibliographic information source on the Internet. PubMed has been considered one of the most important and reliable sources of up-to-date health care evidence. Previous studies examined the effects of domain expertise/knowledge on search performance using PubMed. However, very little is known about PubMed users’ knowledge of information retrieval (IR) functions and their usage in query formulation. Objective The purpose of this study was to shed light on how experienced/nonexperienced PubMed users perform their search queries by analyzing a full-day query log. Our hypotheses were that (1) experienced PubMed users who use system functions quickly retrieve relevant documents and (2) nonexperienced PubMed users who do not use them have longer search sessions than experienced users. Methods To test these hypotheses, we analyzed PubMed query log data containing nearly 3 million queries. User sessions were divided into two categories: experienced and nonexperienced. We compared experienced and nonexperienced users per number of sessions, and experienced and nonexperienced user sessions per session length, with a focus on how fast they completed their sessions. Results To test our hypotheses, we measured how successful information retrieval was (at retrieving relevant documents), represented as the decrease rates of experienced and nonexperienced users from a session length of 1 to 2, 3, 4, and 5. The decrease rate (from a session length of 1 to 2) of the experienced users was significantly larger than that of the nonexperienced groups. Conclusions Experienced PubMed users retrieve relevant documents more quickly than nonexperienced PubMed users in terms of session length. PMID:26139516

  16. Searching PubMed during a pandemic.

    Directory of Open Access Journals (Sweden)

    Ole Norgaard

    Full Text Available BACKGROUND: The 2009 influenza A(H1N1 pandemic has generated thousands of articles and news items. However, finding relevant scientific articles in such rapidly developing health crises is a major challenge which, in turn, can affect decision-makers' ability to utilise up-to-date findings and ultimately shape public health interventions. This study set out to show the impact that the inconsistent naming of the pandemic can have on retrieving relevant scientific articles in PubMed/MEDLINE. METHODOLOGY: We first formulated a PubMed search algorithm covering different names of the influenza pandemic and simulated the results that it would have retrieved from weekly searches for relevant new records during the first 10 weeks of the pandemic. To assess the impact of failing to include every term in this search, we then conducted the same searches but omitted in turn "h1n1," "swine," "influenza" and "flu" from the search string, and compared the results to those for the full string. PRINCIPAL FINDINGS: On average, our core search string identified 44.3 potentially relevant new records at the end of each week. Of these, we determined that an average of 27.8 records were relevant. When we excluded one term from the string, the percentage of records missed out of the total number of relevant records averaged 18.7% for omitting "h1n1," 13.6% for "swine," 17.5% for "influenza," and 20.6% for "flu." CONCLUSIONS: Due to inconsistent naming, while searching for scientific material about rapidly evolving situations such as the influenza A(H1N1 pandemic, there is a risk that one will miss relevant articles. To address this problem, the international scientific community should agree on nomenclature and the specific name to be used earlier, and the National Library of Medicine in the US could index potentially relevant materials faster and allow publishers to add alert tags to such materials.

  17. PubMed Interact: an Interactive Search Application for MEDLINE/PubMed

    Science.gov (United States)

    Muin, Michael; Fontelo, Paul; Ackerman, Michael

    2006-01-01

    Online search and retrieval systems are important resources for medical literature research. Progressive Web 2.0 technologies provide opportunities to improve search strategies and user experience. Using PHP, Document Object Model (DOM) manipulation and Asynchronous JavaScript and XML (Ajax), PubMed Interact allows greater functionality so users can refine search parameters with ease and interact with the search results to retrieve and display relevant information and related articles. PMID:17238658

  18. Etik i kollektivt biografiarbejde med mødre til ‘børn i vanskeligheder’

    DEFF Research Database (Denmark)

    Mørck, Line Lerche; Birk Carlsen, Hedi; Grøndahl, Anja

    2011-01-01

    Denne artikels tilgang til etik indeholder bud på forskningsmetodologi og social praksis etik, der bevæger sig ”on the edge” (Wyatt & Davies, 2011:124), og udfordrer den mere udbredte institutionaliserede etik (Badiou, 2002). Institutionaliseret etik har typisk form af universelle standarder, som...

  19. Nyutdannede allmennlærere og deres opplevelse av faglig kompetanse i leseopplæring generelt og av elever med lesevansker spesielt

    Directory of Open Access Journals (Sweden)

    Gerd Grimsæth

    2015-09-01

    Full Text Available Teoretisk og praktisk kunnskap fungerer etter ulik logikk, ingen teori kan helt omsettes til praksis. Det er derfor av interesse å undersøke nærmere hvordan nyutdannede lærere opplever både sin fagkunnskap og nyervervede kompetanse i yrket. Undersøkelsen som her blir presentert har følgende problemstilling: Hvordan opplever nyutdannede lærere sin kompetanse i leseopplæring generelt og leseopplæring av elever med lesevansker spesielt? Denne pilotundersøkelsen tar utgangspunkt i Q- metoden; nyutdannede lærere plasserer subjektive utsagn trykt på individuelle kort i en matrise. Pilotundersøkelsen baserer seg på 10 respondenter, vi valgte derfor en kvalitativ analyse av resultatene av Q-sorteringen. Resultatene viser at nyutdannede lærere opplever at de mangler kunnskap og kompetanse både i praktisk leseopplæring generelt og om lesevansker spesielt. Kartleggingsmateriell blir i liten grad brukt som grunnlag for informantenes tilrettelegging av arbeidsmåter i leseopplæring. Inkludering og sammenholdte klasser står sterkt hos informantene, men de savner informasjon om elever med lesevansker og om tilgjengelig hjelpemateriell. Resultatene understreker betydningen av veiledning av nyutdannede lærere og ikke minst deres behov for fora for faglig utvikling, faglig utveksling og refleksive diskusjoner.Nøkkelord: Nyutdannede allmennlærere; opplevd fagkunnskap og kompetanse; leseopplæring, lesevansker, Q-metodologi, læring i praksis.AbstractTheory and practice are based on different logics; this means that no theory can be fully implemented in practice. For this reason, it is interesting to investigate newly qualified teachers’ perceptions of their expertise and competence. In order to study this phenomena, the following research question was formulated: How do newly qualified teachers perceive their competence in the field of reading education in general and reading difficulties in particular? This pilot study is based on Q

  20. El edu-entretenimiento en la comunicación para el desarrollo

    DEFF Research Database (Denmark)

    Tufte, Thomas

    2008-01-01

    Artiklen opstiller en heuristic model for fortolkning af de forskellige former for 'edutainment' som anvendes i udviklingskommunikation i praksis. På grundlag af forfatterens erfaringer med edutainment skitseres 3 forskellige 'generationer' indenfor denne kommunikationsstrategiske praksis, kendt ...

  1. Mindfulness som smertehåndteringsredskab for kvinder med endometriose

    DEFF Research Database (Denmark)

    Jensen, Mette Kold; Vedsted-Hansen, Hanne; Hansen, Tia G. B.

    2011-01-01

    Endometriose er en kronisk underlivssygdom med smerter og en række afledte problemer, som ikke nødvendigvis kan behandles med lægelige tiltag. Artiklen argumenterer for, at en mindfulness-baseret tilgang med fokus på smertehåndtering kan anvendes til denne klientgruppe. I vestlig terapeutisk...... sammenhæng kan mindfulness karakteriseres som nærvær, observation og beskrivelse af sansninger uden vurdering eller reaktion. Mindfulness-træning har effekt mod andre typer stress og kroniske smerter, og artiklen opridser et koncept til anvendelse ved endometriose. Konceptet belyses med en case, hvor...

  2. PubMed Informer: Monitoring MEDLINE/PubMed through E-mail Alerts, SMS, PDA downloads and RSS feeds

    Science.gov (United States)

    Muin, Michael; Fontelo, Paul; Ackerman, Michael

    2005-01-01

    Summary PubMed Informer is a Web-based monitoring tool for topics of interest from MEDLINE/PubMed primarily designed for healthcare professionals. Five tracking methods are available: Web access, e-mail, Short Message Service (SMS), PDA downloads and RSS feeds. PubMed Informer delivers focused search updates and specific information to users with varying information-seeking practices. PMID:16779344

  3. Mars 2020 Entry, Descent and Landing Instrumentation (MEDLI2)

    Science.gov (United States)

    Bose, Deepak; Wright, Henry; White, Todd; Schoenenberger, Mark; Santos, Jose; Karlgaard, Chris; Kuhl, Chris; Oishi, TOmo; Trombetta, Dominic

    2016-01-01

    This paper will introduce Mars Entry Descent and Landing Instrumentation (MEDLI2) on NASA's Mars2020 mission. Mars2020 is a flagship NASA mission with science and technology objectives to help answer questions about possibility of life on Mars as well as to demonstrate technologies for future human expedition. Mars2020 is scheduled for launch in 2020. MEDLI2 is a suite of instruments embedded in the heatshield and backshell thermal protection systems of Mars2020 entry vehicle. The objectives of MEDLI2 are to gather critical aerodynamics, aerothermodynamics and TPS performance data during EDL phase of the mission. MEDLI2 builds up the success of MEDLI flight instrumentation on Mars Science Laboratory mission in 2012. MEDLI instrumentation suite measured surface pressure and TPS temperature on the heatshield during MSL entry into Mars. MEDLI data has since been used for unprecedented reconstruction of aerodynamic drag, vehicle attitude, in-situ atmospheric density, aerothermal heating, transition to turbulence, in-depth TPS performance and TPS ablation. [1,2] In addition to validating predictive models, MEDLI data has highlighted extra margin available in the MSL forebody TPS, which can potentially be used to reduce vehicle parasitic mass. MEDLI2 expands the scope of instrumentation by focusing on quantities of interest not addressed in MEDLI suite. The type the sensors are expanded and their layout on the TPS modified to meet these new objectives. The paper will provide key motivation and governing requirements that drive the choice and the implementation of the new sensor suite. The implementation considerations of sensor selection, qualification, and demonstration of minimal risk to the host mission will be described. The additional challenges associated with mechanical accommodation, electrical impact, data storage and retrieval for MEDLI2 system, which extends sensors to backshell will also be described.

  4. Effect of intensive multifactorial treatment compared with routine care on aortic stiffness and central blood pressure among individuals with screen-detected type 2 diabetes

    DEFF Research Database (Denmark)

    Johansen, Nanna Borup; Charles, Morten; Vistisen, Dorte

    2012-01-01

    Baggrund: Interventionsstudier med kardiovaskulære endepunkter kræver meget store studie populationer og/eller en lang opfølgningstid. Intermediære endepunkter som ligger i den kausale gangsti mod klinisk relevante endpunkter er derfor brugbare redskaber til at vurdere effekten af behandling i...... studie som mangler tilstrækkelig kardiovaskulære tilfælde. Aorta stivhed er et anerkendt intermediært endemål i kliniske studier. I ADDITION Danmark studiet fik en del af deltagerne ved 6 års opfølgningsundersøgelsen undersøgt aortisk stivhed, målt ved karotid-femoral pulsbølge hastighed. Vi undersøgte...... herigennem effekten af intensiv multifaktoriel behandling sammenlignet med rutine behandling i almen praksis. Resultater: Patienterne in intensiv gruppen havde en 0,51 m/s (95%CI: -0,96; -0,05; p-værdi:0.03) sammenlignet med rutine behandlingsgruppen. Ekstrapolering af disse resultater på basis af en meta...

  5. Mellem nyliberalisme og terror - Interview med Chantal Mouffe

    DEFF Research Database (Denmark)

    Hansen, Allan Dreyer; Sonnichsen, André

    2012-01-01

    Interview med Chantal Mouffe om Hegemony and Socalist Strategy, modstandere og fjender en ny multipolær verdensorden og demokrati......Interview med Chantal Mouffe om Hegemony and Socalist Strategy, modstandere og fjender en ny multipolær verdensorden og demokrati...

  6. Psykomotorisk behandling og wellness til personer med demens

    DEFF Research Database (Denmark)

    Stamp, Anne Schinkel; Frausing, Kristian Park

    Rapporten evaluerer projektet Psykomotorisk behandling af personer med demens gennem fokusgruppeinterviews med deltagende studerende og personale fra deltagende centre. Samlet peges der på gavnligt udbytte for de demente beboere samt både personligt og fagligt udbytte for de deltagende studerende...

  7. PubMed Medical Publications From Libya | Bakoush | Libyan ...

    African Journals Online (AJOL)

    We also used the same method to obtain data on the PubMed medical publications from Tunisia, Morocco and Yemen. Tunisia had the largest number of PubMed publications among the studied countries: 20.4 publications per million population per year and 7.2 publications per year per one billion US$ GDP. Libya had ...

  8. Musikterapi med kontakt- og kommunikationssvage børn

    DEFF Research Database (Denmark)

    Frederiksen, Britta Vinkler

    2009-01-01

    I artiklen beskrives, hvordan musikterapi er med til at støtte en målrettet udviklingsproces hos børn, med diagnoser som Asperger syndrom, autisme, opmærksomhedsforstyrrelser, ADHD o.lign. Musikkens kvaliteter beskrives og illustreres gennem vignetter fra terapiforløb, der alle er foregået i Klinik...

  9. Further confirmation of the MED13L haploinsufficiency syndrome

    NARCIS (Netherlands)

    van Haelst, M.M.; Monroe, G.R.; Duran, K.J.; van Binsbergen, E.; Breur, J.M.P.J.; Giltay, J.C.; van Haaften, G.W.

    MED13L haploinsufficiency syndrome has been described in two patients and is characterized by moderate intellectual disability (ID), conotruncal heart defects, facial abnormalities and hypotonia. Missense mutations in MED13L are linked to transposition of the great arteries and non-syndromal

  10. Et felteksperiment med Kærlighed i Kaos

    DEFF Research Database (Denmark)

    Christensen, Christiane Præstgaard; Scavenius Sonne-Schmidt, Christoffer

    Som et nyt tilbud til danske forældre med børn med ADHD og ADHD-lignende vanskeligheder har ADHDforeningen udviklet forældretræningsprogrammet Kærlighed i Kaos, hvor frivillige hjælper forældre til børn med ADHD, der står med et særligt vanskeligt opdragelsesarbejde. Denne rapport har til formål......, når forældrene stiller krav til børnene. Resultaterne i denne rapport har interesse for fagpersoner, behandlere, undervisere, beslutningstagere, frivillige organisationer, foreninger og de mange nuværende og kommende familier, som dagligt kæmper med adfærdsvanskeligheder – såsom ADHD. Effektmålingen...

  11. Når forventningerne ikke stemmer overens med virkeligheden. En undersøgelse af de studerendes valg og strategier i overgangen til de længere videregående teknat-uddannelser

    Directory of Open Access Journals (Sweden)

    Henriette T. Holmegaard

    2014-03-01

    Full Text Available Denne artikel præsenterer resultater fra et forskningsprojekt, hvor studerende er fulgt fra slutningen af gymnasiet og ind på en lang videregående teknisk eller naturvidenskabelig uddannelse. Fokus er på de studerendes løbende forventningsafstemning i mødet med den nye uddannelse og de forhandlinger, der finder sted over tid, når de studerende forsøger at blive akademisk integreret. Analysen fokuserer på de studerende der oplever dette som særligt vanskeligt. Tre forhandlingsstrategier identificeres: at udholde at ens forventninger ikke bliver indfriet; gentagende afprøvninger af, om det, man møder, kan tilpasses ens forventninger; at indordne og tilpasse sine forventninger til det, man møder. De tre forskellige strategier foldes ud i analysen med konkrete eksempler og viser, at de studerendes iden-titetsarbejde er en vigtig del af progressionen i de studerendes første studieår. Konsekvenserne og implikationerne for praksis diskuteres afslutningsvist.     This paper presents results from a research project where students are followed from the end of upper secondary school into their higher education science programme. We pay particular attention to the students’ continuous negotiation of expectations in relation to the content of their new study programmes and their attempts to become academically integrated. The analysis is focused on those students who found these negotiations difficult. Three negotiation strategies are identified: to endure and just accept that one’s expectations are not honoured; to continuously try to fit what you meet to your expectations; to fit and adjust one’s expectations to what you meet. Cases from the study cohort who used these strategies are identified and these form the basis of the discussion. Particular attention is paid to the importance of students’ ‘identitywork’ in their first year of study and the consequences and implications this has for practice.

  12. The Arabidopsis mediator complex subunits MED16, MED14, and MED2 regulate mediator and RNA polymerase II recruitment to CBF-responsive cold-regulated genes.

    Science.gov (United States)

    Hemsley, Piers A; Hurst, Charlotte H; Kaliyadasa, Ewon; Lamb, Rebecca; Knight, Marc R; De Cothi, Elizabeth A; Steele, John F; Knight, Heather

    2014-01-01

    The Mediator16 (MED16; formerly termed SENSITIVE TO FREEZING6 [SFR6]) subunit of the plant Mediator transcriptional coactivator complex regulates cold-responsive gene expression in Arabidopsis thaliana, acting downstream of the C-repeat binding factor (CBF) transcription factors to recruit the core Mediator complex to cold-regulated genes. Here, we use loss-of-function mutants to show that RNA polymerase II recruitment to CBF-responsive cold-regulated genes requires MED16, MED2, and MED14 subunits. Transcription of genes known to be regulated via CBFs binding to the C-repeat motif/drought-responsive element promoter motif requires all three Mediator subunits, as does cold acclimation-induced freezing tolerance. In addition, these three subunits are required for low temperature-induced expression of some other, but not all, cold-responsive genes, including genes that are not known targets of CBFs. Genes inducible by darkness also required MED16 but required a different combination of Mediator subunits for their expression than the genes induced by cold. Together, our data illustrate that plants control transcription of specific genes through the action of subsets of Mediator subunits; the specific combination defined by the nature of the stimulus but also by the identity of the gene induced.

  13. Relationer i teori og praksis

    DEFF Research Database (Denmark)

    Der er en talemåde hvor man siger, at fisken er den sidste, der opdager vandet. Mens vandet er fiskens element, kan relationer siges at være menneskets element, idet relationer er en grundlæggende forudsætning for vores liv og udvikling. Alligevel har vi ofte svært ved at få øje på den relationel...

  14. Ligestillingspolitik som diskurs og praksis

    DEFF Research Database (Denmark)

    Borchorst, Anette; Dahlerup, Drude

    The book discusses, why Danish policies of gender equality has had a weak organisational basis and a narrow agenda, compared to other Nordic countries. It contains analyses of the concept of gender equality, policies at the national and local level, discourses of affirmative action...

  15. Politisk retorik, curriculum og praksis

    DEFF Research Database (Denmark)

    Kristjansdottir, Bergthora

    2017-01-01

    orienteret fag i en globaliseret verden. Bergthóra Kristjánsdóttir Lektor, ph.d., DPU Aarhus Universitet. Underviser på DAV og masteruddannelsen i dansk som andetsprog. Forsker i uddannelsespolitik på makro- og mikroniveau, herunder minoriteter/majoriteter, curriculum, tosprogethed, dansk og dansk som...

  16. Det sociale arbejdes daglige praksis

    DEFF Research Database (Denmark)

    Johansen, Mette-Louise

    2007-01-01

    Denne artikel beskriver, hvordan Udlændingelovens regler om helbredsbetinget opholdstilladelse præger praksisgørelsen af begrebet "empowerment" på et rehabiliteringscenter for traumatiserede flygtninge. Der sættes fokus på magtrelationen mellem personale og brugere i en periode, hvor de diagnose...... mellem lovgivning, bureaukratisk forvaltning og empowerment i rehabilitering....

  17. Mellem kvalitetsstandarder og klinisk praksis

    DEFF Research Database (Denmark)

    Madsen, Marie Henriette

    2014-01-01

    , so-called kvalitetskoordinatorer, contributed to organisationsændringer i meeting between styringsinitiativer and local Klinisk practice. Konkret shows analysis how kvalitetsstandarder can become et strategically omdrejningspunkt i knytte Klinisk Personale og leadership together across......Ledelse i sundhedsvæsenet is area in which has been great forskningsmæssig attention - including problematiseringen of how the leadership udøves between Nationalt formulerede styringsinitiativer and sundhedsprofessionernes strategies to preserve their autonomi and vidensmonopol. There has led...... to the development of begreber such as hybridledere and hybrid professioner as categories, der formar integrate styringsinitiativernes tools and logikker with respectively academic leadership and sundhedsprofessionernes grundkompetencer. Jeg This article is purpose skruestik, how to a new Aktor in Danish hospitaler...

  18. Teori-praksis i sygeplejerskeuddannelsen

    DEFF Research Database (Denmark)

    Bering Keiding, Tina

    2008-01-01

    differensteoretisk optik, som nok virker kompleks, emn som også tilbyder en betydelige kompleksitetsfølsomhed. Den kompleksitetsfølsomhed som Luhmann tilbyder, peger for det første på, at der må forventes forskelle mellem såvel intention og interaktion, som mellem forskellige interaktionssystemer. Og at denne...... interaktionelt, bidrager til uddannelsen at i hvert tilfælde at overveje om brudte forventninger skal justeres på niveauet for forventninger/intentioner, eller om ændringerne skal søges tilvejebragt i interaktionen. Artiklen bygger på et oplæg holdt på Fagligt Selskab for Undervisende Sygeplejerskers møde...

  19. Til julefrokost med Bjørn & Okay

    DEFF Research Database (Denmark)

    Smith-Sivertsen, Henrik

    2012-01-01

    I denne artikel vises med udgangspunkt i en beskrivelse af et specifikt arrangement med det danske danseorkester Bjørn & Okay, hvordan man optræder inden for denne særlige musiktradition. Bjørn & Okays performative udgangspunkt er, at de, trods en status som landskendt orkester med mange hits, i ...... the audience and constantly telling them what to do. At the same time he and the other musicians actively bond with the audience, both onstage and offstage, which helps building the spirit of community, which is the clear goal of the musical performance....

  20. Frihet & struktur : en kvalitativ studie av skolelivskvalitet hos ungdom med Tourette syndrom

    OpenAIRE

    Siverts, Torstein

    2005-01-01

    Sammendrag. Tittel: Skolelivskvalitet hos ungdom med Tourette Syndrom Med bakgrunn i egen erfaring fra arbeid med elever med Tourette Syndrom i grunnskolen, og i studier i spesialpedagogisk teori og empiri, etterstrebes det i denne studien å utvikle økt forståelse for hva slags erfaringer fra og perspektiver på sitt skoleliv elever med denne funksjonshemmende lidelsen har. Med grunnlag i analyser av intervjuer med elever om deres erfaringer og perspektiver, har jeg prøvd å b...

  1. Geograf med GIS som ledetråd

    DEFF Research Database (Denmark)

    Nielsen, Søren Zebitz

    2013-01-01

    Fra speciale om kortlægning af luft forurening med NO2 i troposfæren målt fra satellit til PhD studerende med fokus på forståelsen af menneskers bevægelsesmønstre i byer. GIS og geodata er den røde tråd der binder de brede interesser indenfor geografi en sammen for denne forskerlærling.......Fra speciale om kortlægning af luft forurening med NO2 i troposfæren målt fra satellit til PhD studerende med fokus på forståelsen af menneskers bevægelsesmønstre i byer. GIS og geodata er den røde tråd der binder de brede interesser indenfor geografi en sammen for denne forskerlærling....

  2. Erfaringer med Journal Club på modul 12

    DEFF Research Database (Denmark)

    Koustrup, Pia; Røge Aagaard, Lene

    2013-01-01

    I Ortopædkirurgisk afdeling, Aarhus Universitets Hospital, har vi i samarbejde med undervisere fra VIA University College udviklet og implementeret studieaktiviteten Journal Club. Studieaktiviteten afvikles indenfor rammerne af den kliniske studiemetode ”Seminar” og den planlagte studieaktivitet ...

  3. Hvad skal vi med Etisk Råd?

    DEFF Research Database (Denmark)

    Ploug, Thomas; Gjerris, Mickey

    2012-01-01

    Det Etiske Råd har for os at se en væsentlig rolle at spille i et åbent og demokratisk samfund som det danske. Vi skal være med til at skabe grobund for de værdidiskussioner, som skal forme fremtidens samfund. Etik er at være i dialog – ikke at kaste med mudder.......Det Etiske Råd har for os at se en væsentlig rolle at spille i et åbent og demokratisk samfund som det danske. Vi skal være med til at skabe grobund for de værdidiskussioner, som skal forme fremtidens samfund. Etik er at være i dialog – ikke at kaste med mudder....

  4. MedWatch Safety Alerts for Human Medical Products

    Data.gov (United States)

    U.S. Department of Health & Human Services — MedWatch alerts provide timely new safety information on human drugs, medical devices, vaccines and other biologics, dietary supplements, and cosmetics. The alerts...

  5. Forsøg med Hi-Con altanelement

    DEFF Research Database (Denmark)

    Hansen, Lars Pilegaard

    Denne rapport beskriver forsøg udført på Laboratoriet for Bærende Konstruktioner, Aalborg Universitet med et altanelement leveret af Hi-Con Aps, Hjallerup. Forsøgene er udført i september 2002. Forsøgene omfatter en statisk prøvning, hvor altanelementet blev belastet med sandsække og nedbøjningerne...

  6. Spilleregler i musikterapi med børn

    DEFF Research Database (Denmark)

    Holck, Ulla

    2005-01-01

    Artiklen gennemgår udvalgte eksempler på anvendelse af spilleregler i musikterapi med børneklientgrupper. Efter en kort introduktion af Priestleys syn på analytisk musikterapi med børn, præsenteres læseren således for en række caseeksempler fra faglitteraturen, der giver indblik i udformning og a...

  7. Nye steder med liv og sjæl?

    DEFF Research Database (Denmark)

    Stender, Marie

    planlæggere, der har skabt dem, udforskes stedernes tilblivelsesproces og sociale liv. Det nye sted opfattes af både beboere og professionelle som en bar mark, og mange kræfter sættes ind på at genfortrylle det med et skær af liv, identitet og historie fra start. Hånd i hånd med branding, virtuelle fora...

  8. MedRate: a wearable against child mortality

    CERN Document Server

    CERN. Geneva

    2018-01-01

    In humanitarian environments, when treating the main causes of child mortality, there are two key vital constants not easily measurable: the heart beat of the foetus and respiration rate of children. During the CERN Medtech:Hack, my team came up with MedRate, an inexpensive wearable able to monitor both. Collaboration is required to make MedRate a reality. Would you join us for a more fair fight against child mortality?

  9. Å forske med kunsten kollaborativt i en fortellerforestillingsproduksjon

    Directory of Open Access Journals (Sweden)

    Mette Bøe Lyngstad

    2018-03-01

    Full Text Available I denne artikkelen viser forskerne, som også er fortellere, hvordan de i utviklingen av sin egen fortellerforestilling forsket med kunsten. Artikkelforfatterne forsøker å vise en selvrefleksivitet og metodologisk bevissthet gjennom hele kunstproduksjonen. De undersøker hvordan en gjennom å forske med kunsten kollaborativt kan koble historiske fakta, fiksjonsfortelling og livsfortelling i en kunstproduksjon. Forskningsartikkelen tar for seg kunstproduksjonens ulike faser som brainstormfase, innsamlingsfase, fortellertekniske fase og utforskingsfase i scenerommet.

  10. PubMed searches: overview and strategies for clinicians.

    Science.gov (United States)

    Lindsey, Wesley T; Olin, Bernie R

    2013-04-01

    PubMed is a biomedical and life sciences database maintained by a division of the National Library of Medicine known as the National Center for Biotechnology Information (NCBI). It is a large resource with more than 5600 journals indexed and greater than 22 million total citations. Searches conducted in PubMed provide references that are more specific for the intended topic compared with other popular search engines. Effective PubMed searches allow the clinician to remain current on the latest clinical trials, systematic reviews, and practice guidelines. PubMed continues to evolve by allowing users to create a customized experience through the My NCBI portal, new arrangements and options in search filters, and supporting scholarly projects through exportation of citations to reference managing software. Prepackaged search options available in the Clinical Queries feature also allow users to efficiently search for clinical literature. PubMed also provides information regarding the source journals themselves through the Journals in NCBI Databases link. This article provides an overview of the PubMed database's structure and features as well as strategies for conducting an effective search.

  11. Tandlæger og personer med en spiseforstyrrelse

    DEFF Research Database (Denmark)

    Gehrt, Charlotte Astrid; Christensen, Lisa Bøge; Klinker, Sabine

    2016-01-01

    Mødet mellem tandlæge og patient med spiseforstyrrelse Introduktion og formål: Det er velkendt, at tandlæger kan spille en rolle i forhold til tidlig identifikation af en spiseforstyrrelse. Der erimidlertid begrænset viden om, hvilke forventninger tandlæger og personer med en spiseforstyrrelse har...... til mødet med hinanden i klinikken, og hvordan dette opleves. Undersøgelsens formål var derfor at få viden om mødet mellem tandlæger og personer med en spiseforstyrrelse. Materialer og metoder: Undersøgelsen var en tværsnitsundersøgelse baseret på to spørgeskemaer udarbejdet til henholdsvis tandlæger...... og personer med en spiseforstyrrelse. I alt 1.405 tandlæger deltog, mens 260 personer med en spiseforstyrrelse besvarede spørgeskemaet. Resultater: Tandlægerne havde større selvrapporteret viden om orale komplikationer ved en spiseforstyrrelse end om spiseforstyrrelser generelt. Størstedelen af...

  12. De fire dimensioner

    DEFF Research Database (Denmark)

    Larsen, Mihail

    De fire dimensioner er en humanistisk håndbog beregnet især på studerende og vejledere inden for humaniora, men kan også læses af andre med interesse for, hvad humanistisk forskning er og kan. Den er blevet til over et langt livs engageret forskning, uddannelse og formidling på Roskilde Universitet...... og udgør på den måde også et bidrag til universitetets historie, som jeg var med til at grundlægge. De fire dimensioner sætter mennesket i centrum. Men det er et centrum, der peger ud over sig selv; et centrum, hvorfra verden anskues, erfares og forstås. Alle mennesker har en forhistorie og en...... fremtid, og udstrakt mellem disse punkter i tiden tænker og handler de i rummet. Den menneskelige tilværelse omfatter alle fire dimensioner. De fire dimensioner udgør derfor også et forsvar for en almen dannelse, der gennemtrænger og kommer kulturelt til udtryk i vores historie, viden, praksis og kunst....

  13. Comparison of PubMed and Google Scholar literature searches.

    Science.gov (United States)

    Anders, Michael E; Evans, Dennis P

    2010-05-01

    Literature searches are essential to evidence-based respiratory care. To conduct literature searches, respiratory therapists rely on search engines to retrieve information, but there is a dearth of literature on the comparative efficiencies of search engines for researching clinical questions in respiratory care. To compare PubMed and Google Scholar search results for clinical topics in respiratory care to that of a benchmark. We performed literature searches with PubMed and Google Scholar, on 3 clinical topics. In PubMed we used the Clinical Queries search filter. In Google Scholar we used the search filters in the Advanced Scholar Search option. We used the reference list of a related Cochrane Collaboration evidence-based systematic review as the benchmark for each of the search results. We calculated recall (sensitivity) and precision (positive predictive value) with 2 x 2 contingency tables. We compared the results with the chi-square test of independence and Fisher's exact test. PubMed and Google Scholar had similar recall for both overall search results (71% vs 69%) and full-text results (43% vs 51%). PubMed had better precision than Google Scholar for both overall search results (13% vs 0.07%, P PubMed searches with the Clinical Queries filter are more precise than with the Advanced Scholar Search in Google Scholar for respiratory care topics. PubMed appears to be more practical to conduct efficient, valid searches for informing evidence-based patient-care protocols, for guiding the care of individual patients, and for educational purposes.

  14. Inkludering av ungdom med minoritetsbakgrunn i NIF-organisert idrett

    Directory of Open Access Journals (Sweden)

    Mari Kristin Sisjord

    2014-10-01

    Full Text Available Norges Idrettsforbund og Olympiske og Paralympiske Komité (NIF har en uttalt målsetting om en åpen og inkluderende idrett. Hvordan kommer dette til uttrykk i den praktiske virksomheten? Denne artikkelen, som bygger på data fra en undersøkelse om likestilling og mangfold i den organiserte idretten (NIF, retter søkelyset mot arbeid med inklusjon av ungdom med minoritetsbakgrunn på ulike organisasjonsnivå i NIF: særforbund, idrettskretser og idrettslag. Datamaterialet er kvalitative intervju med representanter fra ulike organisasjonsnivå. Resultatene viser at NIFs overordnede politikk i varierende grad nedfelles i særforbundenes virksomhet, i idrettskretsene og i idrettslagene. Av særforbundene skiller Fotballforbundet og Klatreforbundet seg ut som aktive pådrivere i arbeidet med inkludering. Mange idrettslag oppfattet slike spørsmål som lite aktuelle i sitt rekrutteringsområde. Representanter for lag som hadde erfaring med inkludering og rekruttering av minoritetsungdom, tilkjennega varierte erfaringer og synspunkter.

  15. TwiMed: Twitter and PubMed Comparable Corpus of Drugs, Diseases, Symptoms, and Their Relations.

    Science.gov (United States)

    Alvaro, Nestor; Miyao, Yusuke; Collier, Nigel

    2017-05-03

    Work on pharmacovigilance systems using texts from PubMed and Twitter typically target at different elements and use different annotation guidelines resulting in a scenario where there is no comparable set of documents from both Twitter and PubMed annotated in the same manner. This study aimed to provide a comparable corpus of texts from PubMed and Twitter that can be used to study drug reports from these two sources of information, allowing researchers in the area of pharmacovigilance using natural language processing (NLP) to perform experiments to better understand the similarities and differences between drug reports in Twitter and PubMed. We produced a corpus comprising 1000 tweets and 1000 PubMed sentences selected using the same strategy and annotated at entity level by the same experts (pharmacists) using the same set of guidelines. The resulting corpus, annotated by two pharmacists, comprises semantically correct annotations for a set of drugs, diseases, and symptoms. This corpus contains the annotations for 3144 entities, 2749 relations, and 5003 attributes. We present a corpus that is unique in its characteristics as this is the first corpus for pharmacovigilance curated from Twitter messages and PubMed sentences using the same data selection and annotation strategies. We believe this corpus will be of particular interest for researchers willing to compare results from pharmacovigilance systems (eg, classifiers and named entity recognition systems) when using data from Twitter and from PubMed. We hope that given the comprehensive set of drug names and the annotated entities and relations, this corpus becomes a standard resource to compare results from different pharmacovigilance studies in the area of NLP. ©Nestor Alvaro, Yusuke Miyao, Nigel Collier. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 03.05.2017.

  16. Beskrivelse af næringsstofomsætning med metabolomics

    DEFF Research Database (Denmark)

    Hedemann, Mette Skou

    2010-01-01

    I et forsøg med mink med lav eller høj foderkonvertering er der blevet taget blodprøver på tre tidspunkter. Blodprøverne er blevet taget i en periode, hvor minkene er blevet fodret restriktivt (en prøve) og i en periode med ad libitum fodring (to prøver). Blodprøverne blev analyseret ved hjælp af...... fra restriktivt fodrede mink end i plasma fra ad libitum fodrede mink - betain og carnitin. Derudover er der en lang række andre metabolitter, som også findes i forskellig koncentration som endnu ikke er identificeret....

  17. Gaps in affiliation indexing in Scopus and PubMed.

    Science.gov (United States)

    Schmidt, Cynthia M; Cox, Roxanne; Fial, Alissa V; Hartman, Teresa L; Magee, Martha L

    2016-04-01

    The authors sought to determine whether unexpected gaps existed in Scopus's author affiliation indexing of publications written by the University of Nebraska Medical Center or Nebraska Medicine (UNMC/NM) authors during 2014. First, we compared Scopus affiliation identifier search results to PubMed affiliation keyword search results. Then, we searched Scopus using affiliation keywords (UNMC, etc.) and compared the results to PubMed affiliation keyword and Scopus affiliation identifier searches. We found that Scopus's records for approximately 7% of UNMC/NM authors' publications lacked appropriate UNMC/NM author affiliation identifiers, and many journals' publishers were supplying incomplete author affiliation information to PubMed. Institutions relying on Scopus to track their impact should determine whether Scopus's affiliation identifiers will, in fact, identify all articles published by their authors and investigators.

  18. Multiple Epiphyseal Dysplasia (MED: A Rare Type of Skeletal Dysplasia

    Directory of Open Access Journals (Sweden)

    Mohammad Imnul Islam

    2012-06-01

    Full Text Available Multiple epiphyseal dysplasia (MED is a congenital disorder of skeletal development that primarily affects the ends of long bones, causing progressive joint and bone inflammation and short stature. Mutations in several genes are responsible for pathogenesis of this disease. We are reporting a case of MED who presented with the complaints of multiple swelling of the joints which was associated with pain during movement for last seven years. The patient had flexion deformity of all the affected joints along with restriction of movement. These were associated with kyphosis, pectus carnitum, knock-knee and short stature. Radiological findings were suggestive of MED. Counseling was done with the parents regarding the etiology, progression and outcome of the disease.DOI: http://dx.doi.org/10.3329/bsmmuj.v5i1.11025 BSMMU J 2012; 5(1:57-60 

  19. Death, dying and informatics: misrepresenting religion on MedLine.

    Science.gov (United States)

    Rodríguez Del Pozo, Pablo; Fins, Joseph J

    2005-07-01

    The globalization of medical science carries for doctors worldwide a correlative duty to deepen their understanding of patients' cultural contexts and religious backgrounds, in order to satisfy each as a unique individual. To become better informed, practitioners may turn to MedLine, but it is unclear whether the information found there is an accurate representation of culture and religion. To test MedLine's representation of this field, we chose the topic of death and dying in the three major monotheistic religions. We searched MedLine using PubMed in order to retrieve and thematically analyze full-length scholarly journal papers or case reports dealing with religious traditions and end-of-life care. Our search consisted of a string of words that included the most common denominations of the three religions, the standard heading terms used by the National Reference Center for Bioethics Literature (NRCBL), and the Medical Subject Headings (MeSH) used by the National Library of Medicine. Eligible articles were limited to English-language papers with an abstract. We found that while a bibliographic search in MedLine on this topic produced instant results and some valuable literature, the aggregate reflected a selection bias. American writers were over-represented given the global prevalence of these religious traditions. Denominationally affiliated authors predominated in representing the Christian traditions. The Islamic tradition was under-represented. MedLine's capability to identify the most current, reliable and accurate information about purely scientific topics should not be assumed to be the same case when considering the interface of religion, culture and end-of-life care.

  20. Death, dying and informatics: misrepresenting religion on MedLine

    Directory of Open Access Journals (Sweden)

    Fins Joseph J

    2005-07-01

    Full Text Available Abstract Background The globalization of medical science carries for doctors worldwide a correlative duty to deepen their understanding of patients' cultural contexts and religious backgrounds, in order to satisfy each as a unique individual. To become better informed, practitioners may turn to MedLine, but it is unclear whether the information found there is an accurate representation of culture and religion. To test MedLine's representation of this field, we chose the topic of death and dying in the three major monotheistic religions. Methods We searched MedLine using PubMed in order to retrieve and thematically analyze full-length scholarly journal papers or case reports dealing with religious traditions and end-of-life care. Our search consisted of a string of words that included the most common denominations of the three religions, the standard heading terms used by the National Reference Center for Bioethics Literature (NRCBL, and the Medical Subject Headings (MeSH used by the National Library of Medicine. Eligible articles were limited to English-language papers with an abstract. Results We found that while a bibliographic search in MedLine on this topic produced instant results and some valuable literature, the aggregate reflected a selection bias. American writers were over-represented given the global prevalence of these religious traditions. Denominationally affiliated authors predominated in representing the Christian traditions. The Islamic tradition was under-represented. Conclusion MedLine's capability to identify the most current, reliable and accurate information about purely scientific topics should not be assumed to be the same case when considering the interface of religion, culture and end-of-life care.

  1. Yrkesforberedelse eller fagopplæring med fagbrev? Med design og håndverk som kontekst

    Directory of Open Access Journals (Sweden)

    Bjørn Magne Aakre

    2013-09-01

    Full Text Available Artikkelen drøfter forholdet mellom yrkesforberedelse og fagopplæring med utgangspunkt i den kombinerte studieretningen formgivingsfag som ble innført i Norge i 1994. I 2006 ble den delt i et programfag under studiespesialiserende fag, og et nytt yrkesfaglig program med betegnelse design og håndverk. Hvilke interesser lå til grunn for endringene, hvor dyptgripende ble de og hvilke overveieleser kan en gjøre i ettertid om forholdet mellom yrkesforberedelse og fagopplæring? Artikkelen søker å svare på spørsmålene ut fra relevante dokumenter og to kvantitative undersøkelser med elever og lærere som informanter. Artikkelen konkluderer med at innholdet forble nokså likt, antall elever ble halvert og at frafallet økte. Det konkluderes videre med at mange forhold bidrar til å legitimere et fag og dets innhold som henholdsvis skolefag, vitenskapsfag eller yrkesfag. Legitimeringen preges ofte av motstridende motiver og interesser, og sjelden bare faglige begrunnelser.

  2. Psykiske problemer

    DEFF Research Database (Denmark)

    Rasmussen, F.D.

    1994-01-01

    Artiklen, der er udformet som en kronik, søger at henlede opmærksomheden på det afsluttede projekt om psykologbistand i almen praksis. Artiklen lægger særlig vægt på de forhold, der må forventes at interessere de praktiserende læger, såsom lægernes uddannelse på området samt relevansen af en ordn...

  3. Sundhedsfremmende natur for mennesker med bevægelseshandicap

    DEFF Research Database (Denmark)

    Stigsdotter, Ulrika K.; Gramkow, Marie C.; Lygum, Victoria L.

    Rapporten bygger på et forskningsprojekt, der er forankret i et partnerskab med Handicapidrættens Videnscenter, Danske Handicaporganisationer, Bevica Fonden og 15. Juni Fonden og ledes af forskergruppen Natur, Sundhed & Design på Københavns Universitet. Desuden deltager Statens Byggeforskningsins...

  4. Udstilling af børn og fostre med misdannelser

    DEFF Research Database (Denmark)

    Meyer, Ion

    2008-01-01

    Artiklen beskriver baggrunden for etableringen af de første anatomiske samlinger og de første samlinger med teratologiske præparater i Sct. Petersborg og Berlin. Den Saxtorphske Samling på Medicinsk Museion indeholder den største samling af teratologiske præparater i Danmark, og bagrunden for sam...

  5. Bedre trafikuheldsdata: Danske erfaringer med brug af forskellige typer trafikuheldsdata

    DEFF Research Database (Denmark)

    Møller, Mette; Clemmensen, Mikkel Bøg; Janstrup, Kira Hyldekær

    bidraget til kvalitetssikring af projektets forskellige dele, og seniorforsker Mette Møller har været overordnet projektansvarlig. Stud. BEng Lars Finn Jensen og stud. BEng Niels Klindt Andersen har varetaget dataindsamling i forbindelse med rundspørgen blandt kommunerne. Vi vil gerne udtrykke en stor tak...

  6. Folkeretlige problemstillinger i forbindelse med konflikten mellem Ukraine og Rusland

    DEFF Research Database (Denmark)

    Buhl, Kenneth Øhlenschlæger

    Konflikten mellem Ukraine og Rusland udgør en trussel mod den internationale retsorden og dermed også hele den europæiske orden. Med henblik på at give et grundlag for at forstå omfanget af dette aspekt af konflikten behandles her lovligheden af nogle af de handlinger, som har været konfliktens...

  7. Opfølgende hjemmebesøg med video

    DEFF Research Database (Denmark)

    Wentzer, Helle

    Denne publikation beskriver erfaringerne fra et udviklingsprojekt, hvor opfølgende hjemmebesøg kombineres med videokonference-teknologi. Projektet har bestået i at gennemføre et eksperiment, hvor video benyttes til at mediere samtalen mellem læge, hjemmesygeplejerske og den ældre medicinske patie...

  8. 47 CFR 95.628 - MedRadio transmitters.

    Science.gov (United States)

    2010-10-01

    ... bands, or at 403.65 MHz in the 402-405 MHz band. (3) MedRadio stations associated with medical body-worn... applicable to medical implant device operation in the 402-405 MHz band. (d) Authorized bandwidth. The... 401-406 MHz band must operate under the control of a monitoring system that incorporates a mechanism...

  9. 9 ikke-narkotikapolitiske faktorer med beskyttende indflydelse

    DEFF Research Database (Denmark)

    Jourdan, Michael

    2007-01-01

    Sverige er verdensmester i lav prævalens. Det kan skyldes den førte narkotikapolitik. Men det kan i følge Tim Boekhut van Solinge også skyldes ikke narkotikapolitiske faktorer med beskyttende indflydelse. 9 sådanne præsenteres byggende på bogen: 'The Swedish System - an in-depth review and analysis...

  10. Med hjerne og hjerte - et aktionsforskningsprojekt om demensomsorg

    DEFF Research Database (Denmark)

    Hansen, Helle Krogh; Rasmussen, Else Marie

    om værdier; individuelle interviews (8 pårørende og 3 frivillige); to kernekvalitetsundersøgelser (4 medarbejdere undersøgte kvaliteter og værdier ud fra D. Ofmans teori om kernekvaliteter); en kernekvalitetsundersøgelse i samarbejde med lederen; SWOT-analyser, udarbejdelse og analyse af...

  11. Aktivistisk med forbehold? Danmark, EU og den amerikanske verdensorden

    DEFF Research Database (Denmark)

    Wivel, Anders

    2017-01-01

    I hvilken grad og hvordan kan dansk europapolitik tolkes som aktivistisk? Dansk europapolitik er karakteriseret ved stor kontinuitet med en kombination af pragmatisk interessevaretagelse og forsøg på dagsordensættende indflydelsesmaksimering på udvalgte værdipolitiske områder. Samtidig er europap...

  12. PubMed Central Canada: Beyond an Open Access Repository?

    Science.gov (United States)

    Nariani, Rajiv

    2013-01-01

    PubMed Central Canada (PMC Canada) represents a partnership between the Canadian Institutes of Health Research (CIHR), the National Research Council's Canada Institute for Scientific and Technical Information (NRC-CISTI), and the National Library of Medicine of the US. The present study was done to gauge faculty awareness about the CIHR Policy on…

  13. One Health – Transdisziplinarität bei ZB MED

    Directory of Open Access Journals (Sweden)

    Seidlmayer, Eva

    2017-12-01

    Full Text Available By supporting disciplinary and interdisciplinary research in the fields of medicine, health care, nutritional, environmental and agricultural sciences ZB MED enables an integrated view on human health. The poster focuses on approach as well as as the underlying concepts. Additionally, the poster presents services for transdisciplinary research in the life sciences.

  14. Aktiv online læring med E-tiviteter

    DEFF Research Database (Denmark)

    Schneider, Maria Viftrup

    Designe e-tiviteter i vidensøgning og dertilhørende læringsobjekter. Udvikling af didaktikken ift blended learning., med anvendelse af Gilly Salmons E-tivities model som ramme for design af studieaktiviteter. Læringsprodukter hører under læringskoncepterne Undervisningsloop, Peer assessment og Fl...... Flipped classroom....

  15. Senior medical students' appraisal of CanMEDS competencies.

    NARCIS (Netherlands)

    Rademakers, J.; Rooy, N. de; Cate, O.T.J. ten

    2007-01-01

    CONTEXT: In 2003 the Dutch Central College of Medical Specialties presented guidelines for the modernisation of all medical specialty training programmes in the Netherlands. These guidelines are based to a large extent on the CanMEDS (Canadian Medical Education Directives for Specialists) 2000

  16. How Complementary and Alternative Medicine Practitioners Use PubMed

    Science.gov (United States)

    Quint-Rapoport, Mia

    2007-01-01

    Background PubMed is the largest bibliographic index in the life sciences. It is freely available online and is used by professionals and the public to learn more about medical research. While primarily intended to serve researchers, PubMed provides an array of tools and services that can help a wider readership in the location, comprehension, evaluation, and utilization of medical research. Objective This study sought to establish the potential contributions made by a range of PubMed tools and services to the use of the database by complementary and alternative medicine practitioners. Methods In this study, 10 chiropractors, 7 registered massage therapists, and a homeopath (N = 18), 11 with prior research training and 7 without, were taken through a 2-hour introductory session with PubMed. The 10 PubMed tools and services considered in this study can be divided into three functions: (1) information retrieval (Boolean Search, Limits, Related Articles, Author Links, MeSH), (2) information access (Publisher Link, LinkOut, Bookshelf ), and (3) information management (History, Send To, Email Alert). Participants were introduced to between six and 10 of these tools and services. The participants were asked to provide feedback on the value of each tool or service in terms of their information needs, which was ranked as positive, positive with emphasis, negative, or indifferent. Results The participants in this study expressed an interest in the three types of PubMed tools and services (information retrieval, access, and management), with less well-regarded tools including MeSH Database and Bookshelf. In terms of their comprehension of the research, the tools and services led the participants to reflect on their understanding as well as their critical reading and use of the research. There was universal support among the participants for greater access to complete articles, beyond the approximately 15% that are currently open access. The abstracts provided by PubMed were

  17. Jokar et al., Afr J Tradit Complement Altern Med. (2016) 13(1):40-44 ...

    African Journals Online (AJOL)

    PROF ADEWUNMI

    Jokar et al., Afr J Tradit Complement Altern Med. ... Shiraz- Iran.3Department of Obstetrics and Gynecology, School of Medicine and maternal- fetal ..... Ann Intern Med 2001; 135(5):344–51. 7. ... Clin Geriatr Med.2008; ... Indian J. Med Res.

  18. Diagnosis of depressed young people-criterion validity of WHO-5 and HSCL-6 in Denmark and Norway

    DEFF Research Database (Denmark)

    Christensen, Kaj Sparle; Haugen, Wenche; Sirpal, Manjit K

    2015-01-01

    Ifølge WHO bidrager depression væsentligt til den globale sygdomsbyrde. Depressioner hos voksne har ofte deres debut i ungdomsårene. Korte, pålidelige depressionsskalaer er fremmende for tidlig identifikation af depressioner. Formålet med denne undersøgelse var at validere WHO-5 og HSCL-6...... spørgeskemaer til opsporing af depression blandt unge. Projektet blev gennemført som et multicenter-studie i almen praksis i Danmark og Norge. I alt 294 unge i alderen 14-16 år deltog ved at besvare et papir- eller webbaseret spørgeskema og gennemførte efterfølgende et Composite International Diagnostic...... Interview (CIDI), som blev brugt som diagnostisk standard. Depression blev i undersøgelsen defineret ud fra ICD-10 kriterier. Kriterievaliditeten blev undersøgt i form af Receiver Operating Curve analyser og cut-offs for depression blev beregnet ved anvendelse af Youden-indekset. Forekomsten af depression...

  19. Vejbygning i områder med permafrost

    DEFF Research Database (Denmark)

    Jørgensen, Anders Stuhr

    2009-01-01

    Siden begyndelsen af 1990’erne er der registreret en markant stigning i den årlige middeltemperatur i Nunavik, Québec Canada. Dette har ført til en reduktion i udbredelsen af permafrost, hvilket truer stabiliteten af lufthavne og veje i området. I sommeren 2007 blev en teststrækning opført i...... Tasiujaq Lufthavn for at studere effekten af tre forskellige metoder, som skal være med til at reducere optøningen af permafrost under landingsbanen. De tre metoder, som er blevet undersøgt, er konvektionskøling (air convection embankment), varmeudtrækning (heat drain) samt et forsøg med ændring af...

  20. Notat om arbejdet med innovation i Randers Kommune

    DEFF Research Database (Denmark)

    Hansen, Morten Balle; Agger Nielsen, Jeppe

    2012-01-01

    for innovation i Randers Kommune, herunder hvordan politikerne inddrages i innovationsprocessen, 5) Hvor tæt skal økonomi og innovationsdagsorden knyttes? 6) Hvordan er innovationsdagsordenen relateret til en overordnet strategi for Randers Kommune? og 7) selve organiseringen af innovationsprocessen. Notatet...... hovedpunkter er; 1) udarbejdelse af de gode innovationsspørgsmål, 2) dobbeltudfordringen med på den ene side at sikre daglig drift og på den anden side at arbejde innovativt, 3) top-down versus bottom-up processer, dvs. hvor meget skal innovationsprocesserne designes og styres? 4) den særlige kontekst......Dette notat udgør en erfaringsopsamling fra innovationsdag i Randers Kommune, d. 13. november 2012. Notatet fremhæver hovedpointerne fra interne og eksterne oplægsholdere og udpeger en række fokuspunkter/problemstillinger for arbejdet med innovation i Randers Kommune. De syv identificerede...

  1. Trafikulykker med ældre bilister - litteraturundersøgelse

    DEFF Research Database (Denmark)

    Siren, Anu Kristiina

    Andelen af ældre mennesker er i disse år hastigt stigende i de industrialiserede lande, herunder i Danmark. Som følge heraf vokser antallet af ældre bilister, og nutidens ældre forbliver aktive og mobile langt op i årene. Da mobilitet er en vigtig del af dagligdagen, skal transportsystemet blandt...... antal ældre trafikanter vil medføre flere sikkerhedsmæssige problemer. Tværtimod ser det ud, som om sikkerheden generelt vil øges i takt med det voksende antal ældre trafikanter. Denne positive udvikling er dog ikke ensbetydende med, at der ikke fortsat skal fokuseres på ældrevenlige løsninger i...

  2. Grønnere skibsfart med modstandsdygtige motorer

    DEFF Research Database (Denmark)

    Lassen, Lisbeth

    2015-01-01

    Udledningen af forurening fra skibsmotorer skal sænkes kraftigt i de kommende år, og derfor står den maritime industri overfor helt nye krav til blandt andet hvilke brændstoffer, man kan bruge. På grund af de nye regler, der begrænser skibenes energiforbrug, er man også begyndt at sejle med nedsa...... foregår i samarbejde med DTU Kemiteknik og MAN Diesel & Turbo....... hastighed. Både de nye brændstoftyper og den nedsatte hastighed giver problemer for skibsmotorerne, problemer som projektet SULCOR, Sulfuric Acid corrosion in Large Marine Diesel Engines, netop har modtaget 16 millioner kr. fra Innovationsfonden til at begynde at løse. Projektet ledes af DTU Mekanik og...

  3. AliBaba: PubMed as a graph.

    Science.gov (United States)

    Plake, Conrad; Schiemann, Torsten; Pankalla, Marcus; Hakenberg, Jörg; Leser, Ulf

    2006-10-01

    The biomedical literature contains a wealth of information on associations between many different types of objects, such as protein-protein interactions, gene-disease associations and subcellular locations of proteins. When searching such information using conventional search engines, e.g. PubMed, users see the data only one-abstract at a time and 'hidden' in natural language text. AliBaba is an interactive tool for graphical summarization of search results. It parses the set of abstracts that fit a PubMed query and presents extracted information on biomedical objects and their relationships as a graphical network. AliBaba extracts associations between cells, diseases, drugs, proteins, species and tissues. Several filter options allow for a more focused search. Thus, researchers can grasp complex networks described in various articles at a glance. http://alibaba.informatik.hu-berlin.de/

  4. Nye didaktiske veje med mobile medier i voksenundervisningen af ordblinde

    DEFF Research Database (Denmark)

    Gjedde, Lisa; Misfeldt, Morten; Levinsen, Karin

    2012-01-01

    afprøvet mobiltelefonen som læringsværktøj i dansk og matematik. I projekter om læring på arbejdspladsen har mobillæring tidligere vist sig at have potentiale for ordblinde og læsesvage. (Gjedde & Gredsted 2005, 2007). Der er bl.a. høstet erfaringer med mobil tale-til-tekst, der først blev udviklet i MELFO...

  5. MED101: a laser-plasma simulation code. User guide

    International Nuclear Information System (INIS)

    Rodgers, P.A.; Rose, S.J.; Rogoyski, A.M.

    1989-12-01

    Complete details for running the 1-D laser-plasma simulation code MED101 are given including: an explanation of the input parameters, instructions for running on the Rutherford Appleton Laboratory IBM, Atlas Centre Cray X-MP and DEC VAX, and information on three new graphics packages. The code, based on the existing MEDUSA code, is capable of simulating a wide range of laser-produced plasma experiments including the calculation of X-ray laser gain. (author)

  6. The medical dictionary for regulatory activities (MedDRA).

    Science.gov (United States)

    Brown, E G; Wood, L; Wood, S

    1999-02-01

    The International Conference on Harmonisation has agreed upon the structure and content of the Medical Dictionary for Regulatory Activities (MedDRA) version 2.0 which should become available in the early part of 1999. This medical terminology is intended for use in the pre- and postmarketing phases of the medicines regulatory process, covering diagnoses, symptoms and signs, adverse drug reactions and therapeutic indications, the names and qualitative results of investigations, surgical and medical procedures, and medical/social history. It can be used for recording adverse events and medical history in clinical trials, in the analysis and tabulations of data from these trials and in the expedited submission of safety data to government regulatory authorities, as well as in constructing standard product information and documentation for applications for marketing authorisation. After licensing of a medicine, it may be used in pharmacovigilance and is expected to be the preferred terminology for international electronic regulatory communication. MedDRA is a hierarchical terminology with 5 levels and is multiaxial: terms may exist in more than 1 vertical axis, providing specificity of terms for data entry and flexibility in data retrieval. Terms in MedDRA were derived from several sources including the WHO's adverse reaction terminology (WHO-ART), Coding Symbols for a Thesaurus of Adverse Reaction Terms (COSTART), International Classification of Diseases (ICD) 9 and ICD9-CM. It will be maintained, further developed and distributed by a Maintenance Support Services Organisation (MSSO). It is anticipated that using MedDRA will improve the quality of data captured on databases, support effective analysis by providing clinically relevant groupings of terms and facilitate electronic communication of data, although as a new tool, users will need to invest time in gaining expertise in its use.

  7. Er genomisk selektion en revolution af avlsarbejdet med mink?

    DEFF Research Database (Denmark)

    Berg, Peer

    2011-01-01

    Genomisk selektion udnytter, at den enkelte mink kan genotypes for tusindvis af genetiske markører. Et dyrs avlsværdi kan skønnes med ret stor sikkerhed på basis af en blod- eller hårprøve, hvor dyrets sæt af genetiske markører bestemmes. Det er altså ikke nødvendigt at registrere minkens egne eg...

  8. MED1 independent activation of endogenous target genes by PPARα

    DEFF Research Database (Denmark)

    Grøntved, Lars; Bugge, Anne K.; Roeder, Robert G.

    The mediator complex serves as a transcriptional co-activator complex by acting as a bridge between promoter-bound transcription factors and the preinitiation complex. Genetic and biochemical studies indicate that nuclear receptors recruit the mediator complex through direct interaction with the ......The mediator complex serves as a transcriptional co-activator complex by acting as a bridge between promoter-bound transcription factors and the preinitiation complex. Genetic and biochemical studies indicate that nuclear receptors recruit the mediator complex through direct interaction...... derived from TRAP220 KO mice. Interestingly, rescue experiments in confluent TRAP220 KO MEFs with different versions of MED1 indicate that the LXXLL motif is not necessary for PPARgamma mediated gene activation (Ge et al, MCB published online ahead of print 2007). By analogy, we show here that MED1...... is dispensable for PPARalpha transcriptional activity in proliferating but is necessary in confluent AML-12 cells and TRAP220 KO MEFs. Collectively this indicates that the PPARs might have adopted an alternative mediator recruitment mechanism that is dispensable of direct interaction with MED1 on endogenous...

  9. Mitigation of Volcanic Risk: The COSMO-SkyMed Contribution

    Science.gov (United States)

    Sacco, Patrizia; Daraio, Maria Girolamo; Battagliere, Maria Libera; Coletta, Alessandro

    2015-05-01

    The Italian Space Agency (ASI) promotes Earth Observation (EO) applications related to themes such as the prediction, monitoring, management and mitigation of natural and anthropogenic hazards. The approach generally followed is the development and demonstration of prototype services, using currently available data from space missions, in particular the COSMO-SkyMed (Constellation of Small Satellites for Mediterranean basin observation) mission, which represents the largest Italian investment in Space System for EO and thanks to which Italy plays a key role worldwide. Projects funded by ASI provide the convergence of various national industry expertise, research and institutional reference users. In this context a significant example is represented by the ASI Pilot Projects, recently concluded, dealing with various thematic, such as volcanoes. In this paper a special focus will be addressed to the volcanic risk management and the contribution provided in this field by COSMO-SkyMed satellite constellation during the last years. A comprehensive overview of the various national and international projects using COSMO-SkyMed data for the volcanic risk mitigation will be given, highlighting the Italian contribution provided worldwide in this operational framework.

  10. [Systematic literature search in PubMed : A short introduction].

    Science.gov (United States)

    Blümle, A; Lagrèze, W A; Motschall, E

    2018-03-01

    In order to identify current (and relevant) evidence for a specific clinical question within the unmanageable amount of information available, solid skills in performing a systematic literature search are essential. An efficient approach is to search a biomedical database containing relevant literature citations of study reports. The best known database is MEDLINE, which is searchable for free via the PubMed interface. In this article, we explain step by step how to perform a systematic literature search via PubMed by means of an example research question in the field of ophthalmology. First, we demonstrate how to translate the clinical problem into a well-framed and searchable research question, how to identify relevant search terms and how to conduct a text word search and a search with keywords in medical subject headings (MeSH) terms. We then show how to limit the number of search results if the search yields too many irrelevant hits and how to increase the number in the case of too few citations. Finally, we summarize all essential principles that guide a literature search via PubMed.

  11. Udvikling af antistoffer efter vaccination mod og podning med PRRSV

    DEFF Research Database (Denmark)

    Sonne Kristensen, Charlotte; Qvist Pawlowski, Mia; Thoning, Henrik

    konkludere, at det er muligt at vaccinere med begge PRRS vacciner på samme tid og opnå antistofsvar for begge typer PRRSV. Husk dog altid at give forskellige vacciner i hver sin side af nakken. Blodprøver fra grisene viste, at de havde dannet antistoffer og blev positive i ELISA-testen for PRRSV Type 1 21......-US samt IPT testene. Disse tests kan dog ikke skelne ”eksotiske” PRRSV subtyper fra de almindelige cirkulerende PRRSV subtyper i Danmark. Forsøget blev gennemført på Lindholm. Der indgik 66 grise fra en Blå SPF+Ap6+Ap12 besætning. Grisene blev ved ankomst fordelt i 4 grupper (VAC-T1, VAC-T2, VAC-T1T2 og...... NON-VAC): VAC-T1 blev vaccineret med Porcilis ® PRRS VET VAC-T2 blev vaccineret med Ingelvac ® PRRS VET VAC-T1T2 fik begge vacciner samtidig i hver sin side af nakken NON-VAC blev ikke vaccineret. Grisene blev gennem hele forsøget observeret dagligt. De fik taget temperatur den første uge efter...

  12. MedRapid--medical community & business intelligence system.

    Science.gov (United States)

    Finkeissen, E; Fuchs, H; Jakob, T; Wetter, T

    2002-01-01

    currently, it takes at least 6 months for researchers to communicate their results. This delay is caused (a) by partial lacks of machine support for both representation as well as communication and (b) by media breaks during the communication process. To make an integrated communication between researchers and practitioners possible, a general structure for medical content representation has been set up. The procedure for data entry and quality management has been generalized and implemented in a web-based authoring system. The MedRapid-system supports the medical experts in entering their knowledge into a database. Here, the level of detail is still below that of current medical guidelines representation. However, the symmetric structure for an area-wide medical knowledge representation is highly retrievable and thus can quickly be communicated into daily routine for the improvement of the treatment quality. In addition, other sources like journal articles and medical guidelines can be references within the MedRapid-system and thus be communicated into daily routine. The fundamental system for the representation of medical reference knowledge (from reference works/books) itself is not sufficient for the friction-less communication amongst medical staff. Rather, the process of (a) representing medical knowledge, (b) refereeing the represented knowledge, (c) communicating the represented knowledge, and (d) retrieving the represented knowledge has to be unified. MedRapid will soon support the whole process on one server system.

  13. Role for the MED21-MED7 Hinge in Assembly of the Mediator-RNA Polymerase II Holoenzyme*

    Science.gov (United States)

    Sato, Shigeo; Tomomori-Sato, Chieri; Tsai, Kuang-Lei; Yu, Xiaodi; Sardiu, Mihaela; Saraf, Anita; Washburn, Michael P.; Florens, Laurence; Asturias, Francisco J.; Conaway, Ronald C.

    2016-01-01

    Mediator plays an integral role in activation of RNA polymerase II (Pol II) transcription. A key step in activation is binding of Mediator to Pol II to form the Mediator-Pol II holoenzyme. Here, we exploit a combination of biochemistry and macromolecular EM to investigate holoenzyme assembly. We identify a subset of human Mediator head module subunits that bind Pol II independent of other subunits and thus probably contribute to a major Pol II binding site. In addition, we show that binding of human Mediator to Pol II depends on the integrity of a conserved “hinge” in the middle module MED21-MED7 heterodimer. Point mutations in the hinge region leave core Mediator intact but lead to increased disorder of the middle module and markedly reduced affinity for Pol II. These findings highlight the importance of Mediator conformation for holoenzyme assembly. PMID:27821593

  14. Retrieval of diagnostic and treatment studies for clinical use through PubMed and PubMed's Clinical Queries filters.

    Science.gov (United States)

    Lokker, Cynthia; Haynes, R Brian; Wilczynski, Nancy L; McKibbon, K Ann; Walter, Stephen D

    2011-01-01

    Clinical Queries filters were developed to improve the retrieval of high-quality studies in searches on clinical matters. The study objective was to determine the yield of relevant citations and physician satisfaction while searching for diagnostic and treatment studies using the Clinical Queries page of PubMed compared with searching PubMed without these filters. Forty practicing physicians, presented with standardized treatment and diagnosis questions and one question of their choosing, entered search terms which were processed in a random, blinded fashion through PubMed alone and PubMed Clinical Queries. Participants rated search retrievals for applicability to the question at hand and satisfaction. For treatment, the primary outcome of retrieval of relevant articles was not significantly different between the groups, but a higher proportion of articles from the Clinical Queries searches met methodologic criteria (p=0.049), and more articles were published in core internal medicine journals (p=0.056). For diagnosis, the filtered results returned more relevant articles (p=0.031) and fewer irrelevant articles (overall retrieval less, p=0.023); participants needed to screen fewer articles before arriving at the first relevant citation (p<0.05). Relevance was also influenced by content terms used by participants in searching. Participants varied greatly in their search performance. Clinical Queries filtered searches returned more high-quality studies, though the retrieval of relevant articles was only statistically different between the groups for diagnosis questions. Retrieving clinically important research studies from Medline is a challenging task for physicians. Methodological search filters can improve search retrieval.

  15. Når forventningerne ikke stemmer overens med virkeligheden. En undersøgelse af de studerendes valg og strategier i overgangen til de længere videregående teknat-uddannelser

    Directory of Open Access Journals (Sweden)

    Henriette T. Holmegaard

    2014-03-01

    Full Text Available Denne artikel præsenterer resultater fra et forskningsprojekt, hvor studerende er fulgt fra slutningen af gymnasiet og ind på en lang videregående teknisk eller naturvidenskabelig uddannelse. Fokus er på de studerendes løbende forventningsafstemning i mødet med den nye uddannelse og de forhandlinger, der finder sted over tid, når de studerende forsøger at blive akademisk integreret. Analysen fokuserer på de studerende der oplever dette som særligt vanskeligt. Tre forhandlingsstrategier identificeres: at udholde at ens forventninger ikke bliver indfriet; gentagende afprøvninger af, om det, man møder, kan tilpasses ens forventninger; at indordne og tilpasse sine forventninger til det, man møder. De tre forskellige strategier foldes ud i analysen med konkrete eksempler og viser, at de studerendes iden-titetsarbejde er en vigtig del af progressionen i de studerendes første studieår. Konsekvenserne og implikationerne for praksis diskuteres afslutningsvist.  This paper presents results from a research project where students are followed from the end of upper secondary school into their higher education science programme. We pay particular attention to the students’ continuous negotiation of expectations in relation to the content of their new study programmes and their attempts to become academically integrated. The analysis is focused on those students who found these negotiations difficult. Three negotiation strategies are identified: to endure and just accept that one’s expectations are not honoured; to continuously try to fit what you meet to your expectations; to fit and adjust one’s expectations to what you meet. Cases from the study cohort who used these strategies are identified and these form the basis of the discussion. Particular attention is paid to the importance of students’ ‘identitywork’ in their first year of study and the consequences and implications this has for practice. 

  16. Hva med de gjenstridige dokumentene? Fagreferentrollen i spesialsamlinger

    Directory of Open Access Journals (Sweden)

    Solveig Greve

    2010-07-01

    Full Text Available Spesialsamlinger er samlinger av ”gjenstridige dokumenter”, dvs. dokumenter som er sjeldne, unika eller upubliserte og derfor ofte er fysisk bundet til eierinstitusjonen. Det er typisk at slike samlinger mangler moderne standarder for metadata og felles nasjonale katalogiseringsverktøy. Eierinstitusjonene har et kulturansvar for bevaring og tilgjengeliggjøring av disse dokumentene overfor en bredere allmennhet enn et fagbiblioteks ”primærbrukere”. Fagreferentens oppgaver vil være preget av dette. Bevaring, sikring og produksjon av digitale fulltekstdokumenter er sentralt. Det er også typisk for slike samlinger at en har en betydelig backlog. Det vil være fagreferentens oppgave å løfte fram ukjent kildemateriale, gjennom digitaliseringsprosjekter og forskning. Fagreferentens viktigste oppgaver vil da være mer rettet mot samlingspleie og formidling av egne samlinger og mindre fokus på andre institusjoners samlinger. Slik vil også undervisningen av studentene bli preget av arkivpresntasjon av innhold og forelesninger om teoretiske og praktiske forhold knyttet til å arbeide med spesielle materialtyper og mindre til utvikling av vanlig informasjonskompetanse. Denne situasjonen vil forandre seg hvis/når institusjonene blir enige om utvekslingsformater og mengden av digitale fulltekstdokumenter øker. Utfordringene for spesialsamlinger vil også være fagreferentenes utfordringer; I en stadig mer elektronisk verden, kan arbeidet med de fysiske samlingene lett bli marginalisert, selv om nettopp den tekniske utviklingen kunne løse mange problemer for de gjenstridige dokumentene. Men slik prioritering krever store ressurser, høy kompetanse, engasjement og politisk gjennomslagskraft. Kostnadene er høye, og konkurrerer budsjettmessig med galopperende elektroniske utgifter for hele biblioteket. Spesialsamlingenes fagreferenter kan bli en minoritetsstemme i bibliotekenes moderniseringsprosess, til skade for bibliotekenes totale faglige

  17. Applications of medical wireless LAN systems (MedLAN)

    OpenAIRE

    Banitsas, KA; Istepanian, RSH; Tachakra, S

    2002-01-01

    This is a post-peer-review, pre-copyedit version of an article published in Journal of Medical Marketing. The definitive publisher-authenticated version "Konstantinos A. Banitsas, R.S.H. Istepanian, Sapal Tachakra. Applications of medical Wireless LAN systems (MedLAN). Journal of Medical Marketing, Volume 2, Number 2, 1 January 2002 , pp. 136-142(7)" is available online at: http://www.ingentaconnect.com/content/pal/jomm/2002/00000002/00000002/art00008. In this paper the Wireless LAN (WLAN)...

  18. Delivery of Special Magnets for the MedAustron Project

    CERN Document Server

    Kramer, T; Barlow, R A; Barnes, MJ; Borburgh, J; Ducimetière, L; Fowler, T; Hourican, M; Mertens, V; Prost, A

    2014-01-01

    Ten different types of kickers, bumpers, and electrostatic and magnetic septa, along with certain power supplies and associated control system components, have been designed in a collaboration between CERN and MedAustron for an ion therapy centre in Wr. Neustadt (Austria). This paper focuses on the status of the special magnets work package and the improvements applied during the production. The design parameters are compared with data from measurements, hardware test and initial commissioning. The major factors contributing to the successful completion of the work package are highlighted.

  19. Tracking Studies of the MedAustron HEBT

    CERN Document Server

    Schönauer, H

    2014-01-01

    The design of the HEBT, the High Energy Beam Transfer line of the MedAustron Hadron Therapy Centre is based on new concepts developed in the CERN PIMMS Study of the Nineties. One of those is the ‘bar-of-charge’, a very realistic description of the particularities of the horizontal phase space distribution of the slow-extracted beams. Tracking a distribution - produced by simulation of the slow extraction - from the electrostatic septum through the modules of the transfer line gives the sometimes rather particular phase space distributions and their projections at the monitors. Knowing the theoretical phase space distributions there is helpful in the interpretation of the profiles observed.

  20. Dilemmaer i musikterapeutisk behandling af en traumatiseret flygtning med musikerbaggrund

    Directory of Open Access Journals (Sweden)

    Bolette Daniels Beck

    2016-12-01

    Full Text Available Denne artikel præsenterer et single case-studie af et receptivt musikterapiforløb med en 55-årig syrisk flygtning, som har været udsat for fængsling og tortur på grund af sine aktiviteter som protestsanger og musiker. Der beskrives problemstillinger og dilemmaer relateret til at anvende musik, der både kan trigge traumer, men også vække indre ressourcer. Kortlægning af patientens forskellige personlighedsdele og musikkens evne til integration af dem vil blive belyst gennem teorien om strukturel dissociation.

  1. Arbejdspladsvurdering i små virksomheder med 1-4 ansatte

    DEFF Research Database (Denmark)

    Hasle, Peter; Esben, Dalskinn

    En analyse af mulighederne for at gennemføre arbejdspladsvurdering i mikrovirksomheder med 1-4 ansatte.......En analyse af mulighederne for at gennemføre arbejdspladsvurdering i mikrovirksomheder med 1-4 ansatte....

  2. MedlinePlus FAQ: MedlinePlus and MEDLINE/PubMed

    Science.gov (United States)

    ... What is the difference between MedlinePlus and MEDLINE/PubMed? To use the sharing features on this page, ... latest health professional articles on your topic. MEDLINE/PubMed: Is a database of professional biomedical literature Is ...

  3. Quince años de MedUNAB

    Directory of Open Access Journals (Sweden)

    Natalia Hérnandez Rey

    2013-08-01

    Full Text Available Para conmemorar los quince años de MedUNAB el comité estudiantil quiso escribir sobre el significado que tiene para cada uno de sus miembros pertenecer a ella. Es así como en este editorial recogemos las distintas experiencias que se han tenido, algunas de años, otras de meses. MedUNAB es una escuela editorial que hace posible que tres veces al año la comunidad académica de Latinoamérica cuente, tanto física como virtualmente, con una revista científica del área de la salud. Los miembros del comité estudiantil son seleccionados por el editor y por los integrantes con más antigüedad después de hacer un entrenamiento en el cual se aprenden las bases para el proceso editorial que va desde la recepción de los artículos, hasta cómo hacer llegar la revista a cada uno de ustedes en aulas de clase, congresos, simposios, charlas y consultorios, pasando por la evaluación de los escritos, basada en los estrictos parámetros internacionales, la búsqueda de revisores calificados, la corrección de estilo y la diagramación.

  4. Metal waste (Cu and Ni) prevention by SLM and MED

    Energy Technology Data Exchange (ETDEWEB)

    Van de Voorde, I.; Vander Linden, J.; De Ketelaere, R. F. [Chemical and Biochemical Research Centre KaHo Sint-Lieven (CBOK), Ghent (Belgium)

    2001-07-01

    Results of an investigation into implementing supported liquid membranes (SLM) and modified electrodialysis (MED) technology for the recovery of copper and nickel from electroplating effluents in order to prevent metal waste, are discussed. To date, the study of the influence of the individual parameters and their aggregate effect on mass transfer has been completed on laboratory scale equipment. The SLM pilot plant has also been tested extensively, confirming the feasibility of the technique for use with solutions containing up to 500 ppm of metal, as well as for use with other solutions with low metal concentrations originating in other than plating shops. A modified electrodialysis unit also has been designed and constructed using solid ion exchangers. Although development of the technique of electrolytic regeneration and simultaneous conditioning of solid ion exchangers has been successfully completed, the PARCOM 0.5 ppm level envisaged for the deionisation of nickel salts, has not been achieved. Development of the entire control system for SLM and more experiments for MED to replace the ion exchanger membranes, and the effective nickel ion exchanger, by one simple ceramic cell of variable porosity, are the next steps. 7 refs., 3 tabs.

  5. MedAustron – Non-Clinical Research Opportunities

    International Nuclear Information System (INIS)

    Schreiner, T.

    2013-01-01

    MedAustron is a synchrotron based light-ion beam therapy centre for cancer treatment as well as for clinical and non-clinical research, currently in the construction phase in Wiener Neustadt. Whilst the choice of basic machine parameters was driven by medical requirements, the accelerator complex design was also optimised to offer flexibility for research operation. The potential of the synchrotron is being exploited to increase the maximum proton energy far beyond the medical needs to up to 800 MeV, for experimental physics applications, mainly in the areas of proton scattering and detector research. The accelerator layout allows for the installation of up to four ion source-spectrometer units, to provide various ion types besides the clinical used protons and carbon ions. To decouple research and medical operation, a dedicated irradiation room for non-clinical research was included providing two isocentres for the installation of different experiments. This presentation provides a status overview over the whole project and highlights the non-clinical research opportunities at MedAustron. (author)

  6. CredibleMeds.org: What does it offer?

    Science.gov (United States)

    Woosley, Raymond L; Black, Kristin; Heise, C William; Romero, Klaus

    2018-02-01

    Since the 1990s, when numerous non-cardiac drugs were first recognized to have the potential to prolong the QT interval and cause torsades de pointes (TdP), clinicians, drug regulators, drug developers, and clinical investigators have become aware of the complexities of assessing evidence and determining TdP causality for the many drugs being marketed or under development. To facilitate better understanding, the Arizona Center for Education and Research on Therapeutics, known as AZCERT, has developed the CredibleMeds.org website which includes QTdrugs, a listing of over 220 drugs placed in four risk categories based on their association with QT prolongation and TdP. Since the site was launched in 1999, it has become the single and most reliable source of information of its kind for patients, healthcare providers, and research scientists. Over 96,000 registered users rely on the QTdrugs database as their primary resource to inform their medication use, their prescribing or their clinical research into the impact of QT-prolonging drugs and drug-induced arrhythmias. The QTdrugs lists are increasingly used as the basis for clinical decision support systems in healthcare and for metrics of prescribing quality by healthcare insurers. A free smartphone app and an application program interface enable rapid and mobile access to the lists. Also, the CredibleMeds website offers numerous educational resources for patients, educators and healthcare providers that foster the safe use of medications. Copyright © 2018 Elsevier Inc. All rights reserved.

  7. MedCast: a discussion support system for cooperative work

    Science.gov (United States)

    Moreno, Ramon A.; Lima, Vinícius; Lopes, Isidro; Gutierrez, Marco A.

    2012-02-01

    The availability of low cost Internet connections and specialized hardware, like webcams and headsets, makes possible the development of solutions for remote collaborative work. These solutions can provide advantages compared to presential meetings, such as: availability of experts on remote locations; lower price compared to presential meetings; creation of online didactic material (e.g. video-classes); richer forms of interaction between participants. These technologies are particularly interesting for continent-sized countries where typically there is a short number of skilled people in remote areas. However, the application of these technologies in medical field represents a special challenge due to the more complex requirements of this area, such as: Provide confidentiality (patient de-identification) and integrity of patient data; Guarantee availability of the system; Guarantee authenticity of data and users; Provide simple and effective user interface; Be compliant with medical standards such as DICOM and HL7. In order to satisfy those requirements a prototype called MedCast is under development whose architecture allows the integration of the Hospital Information System (HIS) with a collaborative tool in compliance with the HIPAA rules. Some of the MedCast features are: videoconferencing, chat, recording of the sessions, sharing of documents and reports and still and dynamic images presentation. Its current version allows the remote discussion of clinical cases and the remote ECG evaluation.

  8. MedAustron - Ion-Beam Therapy and Research Center

    International Nuclear Information System (INIS)

    Schreiner, Thomas; Seemann, Rolf

    2015-01-01

    MedAustron is a synchrotron-based light-ion beam therapy center for cancer treatment as well as for clinical and non-clinical research, currently in the commissioning phase in Wiener Neustadt, Austria. Recently, the first proton beam was transported successfully to one of the four irradiation rooms. Whilst the choice of basic machine parameters was driven by medical requirements, i.e. 60 MeV protons and 120 MeV/A to 400 MeV/A carbon ions, the accelerator complex design was also optimized to offer flexibility for research operation. The potential of the synchrotron is being exploited to increase the maximum proton energy far beyond the medical needs to up to 800 MeV, for experimental physics applications, mainly in the areas of proton scattering and detector research. The accelerator layout allows for the installation of up to four ion source-spectrometer units, to provide various ion types besides the clinical used protons and carbon ions. Besides experimental physics, the two main non-clinical research disciplines are medical radiation physics and radiation biology. To decouple research and medical operation, a dedicated irradiation room for non-clinical research was included providing the installation of different experiments. In addition, several labs have been equipped with appropriate devices for preparing and analyzing radio-biological samples. This presentation gives a status overview over the whole project and highlights the non-clinical research opportunities at MedAustron. (Author)

  9. Digital kommunikation med den offentlige sektor: Styrelser og statslige institutioner

    DEFF Research Database (Denmark)

    Berger, Jesper Bull; Andersen, Kim Normann

    Denne rapport sammenfatter hovedresultaterne for styrelser og statslige organisationer af en undersøgelse gennemført i sommeren 2013 om besvarelse af e-mail og digital post i den statslige, regionale og kommunale sektor. Allerede med eDag3 1. nov. 2010 skulle alle myndigheder have oprettet en...... digital postkasse, som borgerne kunne skrive til. I denne undersøgelse sættes der fokus på myndighedernes besvarelse af den digitale post. Digital post blev bl.a. etableret som et alternativ til almindelig e-mail for at det offentlige kan kommunikere med borgere og virksomheder på en sikker måde, dvs....... uden at uvedkommende kan få adgang til følsomme oplysninger. Fokus for undersøgelsen er hvordan håndterer myndighederne besvarelserne i den digitale postkasse: svarer de på digital post og e-mail, hvor hurtigt svarer de og er svarene brugbare? Vi har også undersøgt besvarelse af e-mail, dels...

  10. Spilleregler i musikterapi med voksne - oversigter fra faglitteraturen

    Directory of Open Access Journals (Sweden)

    Ulla Holck

    2005-02-01

    Full Text Available Artiklen gennemgår udvalgt faglitteratur, der på et overordnet plan beskriver typer af spilleregler i musikterapi med (fortrinsvis voksne klientgrupper. Udgangspunktet er Priestleys anvendelse af begrebet, og hendes inddeling af spilleregler i forhold til forskellige teknikker gennemgås, efterfulgt af en præsentation af opdelinger lavet af henholdsvis Pedersen & Scheiby, Bruscia og Wigram. En af forskellene på opfattelsen af spillereglernes karakter og anvendelse handler om, hvorvidt spillereglerne udelukkende bør have et referentielt indhold med udgangspunkt i klientens psykiske materiale, eller om også rent musikalske (eller nonreferentiellespilleregler kan siges at have en terapeutisk effekt. Artiklens forfatter ser i stedet spørgsmålet i lyset af mange klienters behov for en gradvis introduktion til klinisk improvisation og inddrager i den sammenhæng litteratur om introduktion og assessment af bl.a. Wigram, Hannibal og Jensen. Artiklen er den første i en serie, hvis overordnede mål er at indsamle viden og erfaring om anvendelse af spilleregler i forhold til forskellige klientgrupper. Anden del omhandler udvikling af spilleregler i forhold til børneklientgrupper og findes i næste kapitel i dette årsskrift.

  11. Personalets deltagelse i forebyggelse blandt voksne patienter i almen laegepraksis

    DEFF Research Database (Denmark)

    Hansen, Dorte Gilså; K. Rasmussen, Niels; Munck, Anders P

    2008-01-01

    of the doctors stated that the staff performed tasks in connection with weight control, vaccination of adults, blood pressure checks, lung function tests, alcohol abuse treatment and dietary counselling. A total of 72% of the doctors wished for greater staff involvement within one or more areas, especially...... and size of the practice, and the extent of the regional lack of doctors. CONCLUSION: Staff in general practice perform many preventive tasks related to the eight common chronic diseases, but most frequently in practices where there is a nurse employed. Although the participating doctors may have a special......) the doctors' wishes for increased involvement. MATERIALS AND METHODS: In total, 378 out of 381 general practitioners from ten counties participating in "Audit on prevention in general practice 2004" filled in a two-page questionnaire. RESULTS: Almost all (377/378) had staff employed. More than half...

  12. Forskning i musikterapi - børn med en Autisme Spektrum Forstyrrelse

    DEFF Research Database (Denmark)

    Holck, Ulla

    2011-01-01

    Der er forskningsmæssig evidens for, at musikterapi med børn med en autisme spektrum forstyrrelse (ASF) har en signifikant effekt. Cochrane reviews påviser, at musikterapi fremmer verbal og navnlig nonverbal kommunikation hos børn med ASF. En RCT-undersøgelse viser endvidere en signifikant effekt...

  13. Searching PubMed for molecular epidemiology studies: the case of chromosome aberrations

    DEFF Research Database (Denmark)

    Ugolini, Donatella; Neri, Monica; Knudsen, Lisbeth E

    2006-01-01

    to environmental pollutants. The search, done on the PubMed/MedLine database, was based on a strategy combining descriptors listed in the PubMed Medical Subject Headings (MeSH) Thesaurus and other available tools (free text or phrase search tools). 178 articles were retrieved by searching the period from January 1...

  14. Med5(Nut1) and Med17(Srb4) Are Direct Targets of Mediator Histone H4 Tail Interactions

    Science.gov (United States)

    Liu, Zhongle; Myers, Lawrence C.

    2012-01-01

    The Mediator complex transmits activation signals from DNA bound transcription factors to the core transcription machinery. In addition to its canonical role in transcriptional activation, recent studies have demonstrated that S. cerevisiae Mediator can interact directly with nucleosomes, and their histone tails. Mutations in Mediator subunits have shown that Mediator and certain chromatin structures mutually impact each other structurally and functionally in vivo. We have taken a UV photo cross-linking approach to further delineate the molecular basis of Mediator chromatin interactions and help determine whether the impact of certain Mediator mutants on chromatin is direct. Specifically, by using histone tail peptides substituted with an amino acid analog that is a UV activatible crosslinker, we have identified specific subunits within Mediator that participate in histone tail interactions. Using Mediator purified from mutant yeast strains we have evaluated the impact of these subunits on histone tail binding. This analysis has identified the Med5 subunit of Mediator as a target for histone tail interactions and suggests that the previously observed effect of med5 mutations on telomeric heterochromatin and silencing is direct. PMID:22693636

  15. Med5(Nut1 and Med17(Srb4 are direct targets of mediator histone H4 tail interactions.

    Directory of Open Access Journals (Sweden)

    Zhongle Liu

    Full Text Available The Mediator complex transmits activation signals from DNA bound transcription factors to the core transcription machinery. In addition to its canonical role in transcriptional activation, recent studies have demonstrated that S. cerevisiae Mediator can interact directly with nucleosomes, and their histone tails. Mutations in Mediator subunits have shown that Mediator and certain chromatin structures mutually impact each other structurally and functionally in vivo. We have taken a UV photo cross-linking approach to further delineate the molecular basis of Mediator chromatin interactions and help determine whether the impact of certain Mediator mutants on chromatin is direct. Specifically, by using histone tail peptides substituted with an amino acid analog that is a UV activatible crosslinker, we have identified specific subunits within Mediator that participate in histone tail interactions. Using Mediator purified from mutant yeast strains we have evaluated the impact of these subunits on histone tail binding. This analysis has identified the Med5 subunit of Mediator as a target for histone tail interactions and suggests that the previously observed effect of med5 mutations on telomeric heterochromatin and silencing is direct.

  16. Udkantsdanmark: Avisernes (med)produktion af Nordjyllands territorielle stigma

    DEFF Research Database (Denmark)

    Pristed Nielsen, Helene; Christensen, Sascha

    2013-01-01

    Artiklen undersøger hvordan Region Nordjylland (NJ) beskrives i medierne og hvordan diskursen om Udkanten dominerer avisernes fremstilling af regionen . Baggrunden herfor er en interesse for social ulighed, og i denne sammenhæng Wacquants begreb om territorielt stigma (1996, 2007). Wacquant føjer...... stigma. I Gunnar Lind Haase Svendsens studie af italesættelsen af ’udkanten’ fra 1996-2011 ses fx en gennem de seneste år stigende anvendelse af termer som ’den rådne banan’ og ’Udkantsdanmark’ i medierne (Svendsen 2013: 12). Dette stigma forbindes med flere dele af Danmark (se bl.a. Arbejderbevægelsens...

  17. Lederudvikling med mål og retning

    DEFF Research Database (Denmark)

    Brix, Jacob

    2010-01-01

    Altid et behov for udvikling Vi stopper aldrig med at udvikle os; og hvis vi gør, så fortsætter samfundet sin udvikling. At være leder i år 2010 er ikke det samme som at være leder i 1954, og ledelse i år 2025 er helt sikkert ikke det samme som ledelse i dag. Henry Mintzberg, en meget anerkendt...... canadisk organisations og ledelsesforsker, er kendt for at sige: "you can't create a leader in a classroom!" - som frit tolket betyder: man bliver ikke leder på skolebænken. Mintzberg mener at en rigtig leder først skabes, når vedkommende har praksiserfaring og derefter søger videreuddannelse. For én ting...

  18. Peer til peer i arbejdet med udsatte mennesker

    DEFF Research Database (Denmark)

    Ahlmark, Nanna; Norrhäll, Oskar; Jensen, Pernille Hartvig

    Statens Institut for Folkesundhed, Syddansk Universitet har fået til opdrag at lave en formativ procesevaluering af Københavns Kommunes projekt Mænd i København. Projektet omhandler udvikling og implementering af en peer til peer indsats med henblik på at forbedre sundhed og trivsel blandt udsatte...... mænd i risiko for at udvikle type 2 diabetes. En del af evalueringsopdraget har været at tilvejebringe viden om relevant litteratur om peer-metoder. I denne forbindelse er dette notat udarbejdet til Københavns Kommunes Forebyggelsescenter Nørrebro af evaluerings-teamet, som består af forsker, Nanna...... Ahlmark, adjunkt ved Aalborg Universitet Camilla Dindler, praktikant og specialestuderende Oskar Norrhäll og specialestuderende Pernille Hartvig Jensen. Notatet er en sammenfatning af udvalgt forskningslitteratur og rapporter om peer til peer-relaterede projekter målrettet udsatte grupper i forbindelse...

  19. Et væksthus med lys og varme

    DEFF Research Database (Denmark)

    Birkelund, Regner

    1999-01-01

    sygeplejerskers 'hjemmelavede' uddannelsesmodel? Hvordan tager eksperimentet sig ud i lyset af Grundtvigs højskoletanker? Det konkluderes på disse spørgsmål, at der trods skarp kritik fra flere ortodokse højskolefolk var endog god 'grundtvigsk mening' i det, man foretog sig i Testrup. Med livsoplysning som et...... nytteløse er det nyttigste' i livsoplysningssammenhæng, fremholdes i denne forbindelse som en vigtig grundtvigsk pointe, og for at klargøre relationen mellem denne æstetiske dimension og livsoplysning er Løgstrups etik- og æstetikforståelse blevet inddraget. Der argumenteres for, at Løgstrups opfattelse af...

  20. Produktudvikling af fødevarer med Quality Function Deployment

    DEFF Research Database (Denmark)

    Bech, Anne C.

    1998-01-01

    Produktudvikling af fødevarer stiller stadig større krav til virksomhedernes kompetencer. QFD filosofien kan bidrage til at skabe en fælles forståelse af grundlaget for udvikling af nye produkter. Udgangspunktet er en forståelse af forbrugernes behov i relation til virksomhedens muligheder...... konkurrentprodukter. Efterfølgende faser handler om at generere forskellige mulige løsninger, inden der træffes valg af løsningsalternativ. Anvendelse af QFD modellen for produktudvikling betyder, at forbrugernes behov er centrale i hele produktudviklingsforløbet, samt at det udviklede produkt sigter mod at opfylde...... væsentlige identificerede behov set fra forbrugernes synspunkt. At virksomheden ser implementering af QFD som en investering, medarbejdernes commitment og målrettet projekt, er væsentlig for en succesfuld implementering af QFD til produktudvikling. QFD tankegangen illustreres med et eksempel på udvikling af...

  1. The inclusion of an online journal in PubMed central - a difficult path.

    Science.gov (United States)

    Grech, Victor

    2016-01-01

    The indexing of a journal in a prominent database (such as PubMed) is an important imprimatur. Journals accepted for inclusion in PubMed Central (PMC) are automatically indexed in PubMed but must provide the entire contents of their publications as XML-tagged (Extensible Markup Language) data files compliant with PubMed's document type definition (DTD). This paper describes the various attempts that the journal Images in Paediatric Cardiology made in its efforts to convert the journal contents (including all of the extant backlog) to PMC-compliant XML for archiving and indexing in PubMed after the journal was accepted for inclusion by the database.

  2. OvidSP Medline-to-PubMed search filter translation: a methodology for extending search filter range to include PubMed's unique content.

    Science.gov (United States)

    Damarell, Raechel A; Tieman, Jennifer J; Sladek, Ruth M

    2013-07-02

    PubMed translations of OvidSP Medline search filters offer searchers improved ease of access. They may also facilitate access to PubMed's unique content, including citations for the most recently published biomedical evidence. Retrieving this content requires a search strategy comprising natural language terms ('textwords'), rather than Medical Subject Headings (MeSH). We describe a reproducible methodology that uses a validated PubMed search filter translation to create a textword-only strategy to extend retrieval to PubMed's unique heart failure literature. We translated an OvidSP Medline heart failure search filter for PubMed and established version equivalence in terms of indexed literature retrieval. The PubMed version was then run within PubMed to identify citations retrieved by the filter's MeSH terms (Heart failure, Left ventricular dysfunction, and Cardiomyopathy). It was then rerun with the same MeSH terms restricted to searching on title and abstract fields (i.e. as 'textwords'). Citations retrieved by the MeSH search but not the textword search were isolated. Frequency analysis of their titles/abstracts identified natural language alternatives for those MeSH terms that performed less effectively as textwords. These terms were tested in combination to determine the best performing search string for reclaiming this 'lost set'. This string, restricted to searching on PubMed's unique content, was then combined with the validated PubMed translation to extend the filter's performance in this database. The PubMed heart failure filter retrieved 6829 citations. Of these, 834 (12%) failed to be retrieved when MeSH terms were converted to textwords. Frequency analysis of the 834 citations identified five high frequency natural language alternatives that could improve retrieval of this set (cardiac failure, cardiac resynchronization, left ventricular systolic dysfunction, left ventricular diastolic dysfunction, and LV dysfunction). Together these terms reclaimed

  3. HRM i Danmark efter krisen

    DEFF Research Database (Denmark)

    Bévort, Frans; Holt Larsen, Henrik; Hjalager, Anne-Mette

    Kortlægning af praksis for Human Resource Management (HRM) i alle organisationer i Danmark med mere end 100 ansatte.......Kortlægning af praksis for Human Resource Management (HRM) i alle organisationer i Danmark med mere end 100 ansatte....

  4. Social Medie-strategi og implementering

    DEFF Research Database (Denmark)

    2017-01-01

    20 arbejdsark bygget på en strategimodel for arbejdet med sociale medier. Fra målgruppeudvælgelse til implementering i praksis og måling.......20 arbejdsark bygget på en strategimodel for arbejdet med sociale medier. Fra målgruppeudvælgelse til implementering i praksis og måling....

  5. The Mediterranean Supersite Volcanoes (MED-SUV) Project: an overview

    Science.gov (United States)

    Puglisi, Giuseppe

    2014-05-01

    The EC FP7 MEDiterranean SUpersite Volcanoes (MED-SUV) EC-FP7 Project, which started on June 2013, aims to improve the capacity of the scientific institutions, end users and SME forming the project consortium to assess the volcanic hazards at Italian Supersites, i.e. Mt. Etna and Campi Flegrei/Vesuvius. The Project activities will focus on the optimisation and integration of ground and space monitoring systems, the breakthrough in understanding of volcanic processes, and on the increase of the effectiveness of the coordination between the scientific and end-user communities in the hazard management. The overall goal of the project is to apply the rationale of the Supersites GEO initiative to Mt. Etna and Campi Flegrei/Vesuvius, considered as cluster of Supersites. For the purpose MED-SUV will integrate long-term observations of ground-based multidisciplinary data available for these volcanoes, i.e. geophysical, geochemical, and volcanological datasets, with Earth Observation (EO) data. Merging of different parameters over a long period will provide better understanding of the volcanic processes. In particular, given the variety of styles and intensities of the volcanic activity observed at these volcanoes, and which make them sort of archetypes for 'closed conduit ' and 'open conduit' volcanic systems, the combination of different data will allow discrimination between peculiar volcano behaviours associated with pre-, syn- and post-eruptive phases. Indeed, recognition of specific volcano patterns will allow broadening of the spectrum of knowledge of geo-hazards, as well as better parameterisation and modelling of the eruptive phenomena and of the processes occurring in the volcano supply system; thus improving the capability of carrying out volcano surveillance activities. Important impacts on the European industrial sector, arising from a partnership integrating the scientific community and SMEs to implement together new observation/monitoring sensors/systems, are

  6. Mediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency.

    Directory of Open Access Journals (Sweden)

    Lin Li

    Full Text Available The multi-subunit mammalian Mediator complex acts as an integrator of transcriptional regulation by RNA Polymerase II, and has emerged as a master coordinator of development and cell fate determination. We previously identified the Mediator subunit, MED28, as a cytosolic binding partner of merlin, the Neurofibromatosis 2 (NF2 tumor suppressor, and thus MED28 is distinct in having a cytosolic role as an NF2 interacting protein as well as a nuclear role as a Mediator complex subunit. Although limited in vitro studies have been performed on MED28, its in vivo function remains unknown. Employing a knockout mouse model, we describe for the first time the requirement for Med28 in the developing mouse embryo. Med28-deficiency causes peri-implantation lethality resulting from the loss of pluripotency of the inner cell mass accompanied by reduced expression of key pluripotency transcription factors Oct4 and Nanog. Further, overexpression of Med28 in mouse embryonic fibroblasts enhances the efficiency of their reprogramming to pluripotency. Cre-mediated inactivation of Med28 in induced pluripotent stem cells shows that Med28 is required for their survival. Intriguingly, heterozygous loss of Med28 results in differentiation of induced pluripotent stem cells into extraembryonic trophectoderm and primitive endoderm lineages. Our findings document the essential role of Med28 in the developing embryo as well as in acquisition and maintenance of pluripotency during reprogramming.

  7. Performance requirements of the MedAustron beam delivery system

    CERN Document Server

    AUTHOR|(CDS)2073034

    The Austrian hadron therapy center MedAustron is currently under construction with patient treatment planned to commence in 2015. Tumors will be irradiated using proton and carbon ions, for which the steeply rising Bragg curve and finite range offer a better conformity of the dose to the geometrical shape of the tumor compared to conventional photon irradiation. The current trend is to move from passive scattering toward active scanning using a narrow pencil beam in order to reach an even better dose conformation and limit the need of patient specific hardware. The quality of the deposited dose will ultimately depend on the performance of the beam delivery chain: beam profile and extraction stability of the extracted beam, accuracy and ramp rate of the scanning magnet power supplies, and precision of the beam monitors used for verifying the delivered dose. With a sharp lateral penumbra, the transverse dose fall-off can be minimized. This is of particular importance in situations where the lesion is adjace...

  8. Humant papillomavirus i orale lidelser med malignt potentiale

    DEFF Research Database (Denmark)

    Bjørlig, Xenia; Waage Brinch, Arendse; Kongsmark Madsen, Jonas

    2016-01-01

    – At belyse prævalensen af HPV i OLMP og diskutere betydningen af HPV for malign udvikling af disse forandringer. Materiale og metode – På baggrund af litteratursøgning beskrives, hvordan HPV associeres til OLMP, herunder specifikt leukoplaki, erytroplaki og oral lichen planus samt forekomsten af HPV i sund......Introduktion – Humant papillomavirus (HPV) er i dag anerkendt som den vigtigste enkelte ætiologiske faktor til cervixcancer, og det er nu blevet klart, at der også findes en sammenhæng mellem HPV og undergrupper af hoved-halscancer. Sammenhængen mellem HPV og en andel af orale cancere er også...... undersøgt, særligt grundet den stigende incidens af oral cancer på trods af et fald og en stagnering i forbruget af risikofaktorer som tobak og alkohol. Tandlægen ser ofte orale lidelser med malignt potentiale (OLMP) i mundslimhinden, og mellem 20-50 % af orale cancere menes at forudgås af OLMP. Formål...

  9. Mars Science Laboratory (MSL) Entry, Descent, and Landing Instrumentation (MEDLI): Complete Flight Data Set

    Science.gov (United States)

    Cheatwood, F. McNeil; Bose, Deepak; Karlgaard, Christopher D.; Kuhl, Christopher A.; Santos, Jose A.; Wright, Michael J.

    2014-01-01

    The Mars Science Laboratory (MSL) entry vehicle (EV) successfully entered the Mars atmosphere and landed the Curiosity rover safely on the surface of the planet in Gale crater on August 6, 2012. MSL carried the MSL Entry, Descent, and Landing (EDL) Instrumentation (MEDLI). MEDLI delivered the first in-depth understanding of the Mars entry environments and the response of the entry vehicle to those environments. MEDLI was comprised of three major subsystems: the Mars Entry Atmospheric Data System (MEADS), the MEDLI Integrated Sensor Plugs (MISP), and the Sensor Support Electronics (SSE). Ultimately, the entire MEDLI sensor suite consisting of both MEADS and MISP provided measurements that were used for trajectory reconstruction and engineering validation of aerodynamic, atmospheric, and thermal protection system (TPS) models in addition to Earth-based systems testing procedures. This report contains in-depth hardware descriptions, performance evaluation, and data information of the three MEDLI subsystems.

  10. Tværsektorielt samarbejde ved behandling af patienter med type 2-diabetes

    DEFF Research Database (Denmark)

    Munch, Lene; Røder, Michael E; Hansen, Ida H

    2018-01-01

    Hovedbudskaber • Sundhedsstyrelsen lægger vægt på tværsektorielt samarbejde omkring patienten med type 2-diabetes, men denne tankegang er dog ikke implementeret i det danske sundhedsvæsen • På organisatorisk niveau kan en stratificerings- og forløbsmodel give anvisninger til opgave- og...... udnyttelse af sundhedsvæsenets ressourcer samtidig med, at behandling af høj kvalitet fastholdes og udvikles for patienter med type 2-diabetes...

  11. The MedAustron Project at CERN, Status Report, May 2013

    CERN Document Server

    Benedikt, M; Gutleber, J

    2013-01-01

    MedAustron is a light ion-therapy and research centre based on a synchrotron accelerator complex under construction in Austria. It is the first large-scale accelerator facility in Austria. For the implementation of the required accelerator technologies, the county of Lower Austria and the company EBG MedAustron have set up dedicated agreements with CERN. These cover the assistance of CERN for the design and manufacturing follow-up of accelerator components and training of MedAustron personnel. CERN contributed to the MedAustron construction in particular by providing domain expertise, infrastructure, and manpower in relation with the design, the tendering and procurement processes.\

  12. Mediator Med23 deficiency enhances neural differentiation of murine embryonic stem cells through modulating BMP signaling.

    Science.gov (United States)

    Zhu, Wanqu; Yao, Xiao; Liang, Yan; Liang, Dan; Song, Lu; Jing, Naihe; Li, Jinsong; Wang, Gang

    2015-02-01

    Unraveling the mechanisms underlying early neural differentiation of embryonic stem cells (ESCs) is crucial to developing cell-based therapies of neurodegenerative diseases. Neural fate acquisition is proposed to be controlled by a 'default' mechanism, for which the molecular regulation is not well understood. In this study, we investigated the functional roles of Mediator Med23 in pluripotency and lineage commitment of murine ESCs. Unexpectedly, we found that, despite the largely unchanged pluripotency and self-renewal of ESCs, Med23 depletion rendered the cells prone to neural differentiation in different differentiation assays. Knockdown of two other Mediator subunits, Med1 and Med15, did not alter the neural differentiation of ESCs. Med15 knockdown selectively inhibited endoderm differentiation, suggesting the specificity of cell fate control by distinctive Mediator subunits. Gene profiling revealed that Med23 depletion attenuated BMP signaling in ESCs. Mechanistically, MED23 modulated Bmp4 expression by controlling the activity of ETS1, which is involved in Bmp4 promoter-enhancer communication. Interestingly, med23 knockdown in zebrafish embryos also enhanced neural development at early embryogenesis, which could be reversed by co-injection of bmp4 mRNA. Taken together, our study reveals an intrinsic, restrictive role of MED23 in early neural development, thus providing new molecular insights for neural fate determination. © 2015. Published by The Company of Biologists Ltd.

  13. Med-Ro Hybrid desalination as option to supply fresh water in BABEL Islands Province

    International Nuclear Information System (INIS)

    Siti Alimah; Sudi Ariyanto; June Mellawati; Budiarto

    2011-01-01

    Med-Ro hybrid desalination systems are combining both thermal (Med) and membrane (Ro) desalination processes with power generation systems. This configuration has more economical and operational benefits in comparison with single desalination plant. Hybrid configurations are characterized by flexibility in operation, specific energy consumption (33.50 kWh/m 3 ) is lower than Med (36.54 kWh/m 3 ) and high plant availability. The objective of study is to analyze the Med-Ro hybrid desalination as an option to add supply fresh water in Babel Islands Province, in terms of technology and economy aspects. The result of study showed that adopting nuclear power plants as dual-purpose for power generation and producing fresh water is has economic competitiveness than fossil-fired generation plants. Med-Ro hybrid configuration, with feed Ro from heat rejection of Med system is suitable as fresh water supply add option because increase of Ro feed temperature will increase flux. Economic analysis of water cost are performed using the Deep-3.2. Water cost of hybrid Med-Ro desalination with energy of NPP (0.581 $/m ) is lower than that of Med water cost (0.752 $/m ) . Water cost of hybrid Med-Ro with energy of NPP (0.581 $/m ) is lower than that of water cost of energy with fossil-fired generation plants (0.720 $/m 3 ). (author)

  14. Retrieving clinical evidence: a comparison of PubMed and Google Scholar for quick clinical searches.

    Science.gov (United States)

    Shariff, Salimah Z; Bejaimal, Shayna Ad; Sontrop, Jessica M; Iansavichus, Arthur V; Haynes, R Brian; Weir, Matthew A; Garg, Amit X

    2013-08-15

    Physicians frequently search PubMed for information to guide patient care. More recently, Google Scholar has gained popularity as another freely accessible bibliographic database. To compare the performance of searches in PubMed and Google Scholar. We surveyed nephrologists (kidney specialists) and provided each with a unique clinical question derived from 100 renal therapy systematic reviews. Each physician provided the search terms they would type into a bibliographic database to locate evidence to answer the clinical question. We executed each of these searches in PubMed and Google Scholar and compared results for the first 40 records retrieved (equivalent to 2 default search pages in PubMed). We evaluated the recall (proportion of relevant articles found) and precision (ratio of relevant to nonrelevant articles) of the searches performed in PubMed and Google Scholar. Primary studies included in the systematic reviews served as the reference standard for relevant articles. We further documented whether relevant articles were available as free full-texts. Compared with PubMed, the average search in Google Scholar retrieved twice as many relevant articles (PubMed: 11%; Google Scholar: 22%; PGoogle Scholar: 8%; P=.07). Google Scholar provided significantly greater access to free full-text publications (PubMed: 5%; Google Scholar: 14%; PGoogle Scholar returns twice as many relevant articles as PubMed and provides greater access to free full-text articles.

  15. Connecting the dots between PubMed abstracts.

    Directory of Open Access Journals (Sweden)

    M Shahriar Hossain

    Full Text Available BACKGROUND: There are now a multitude of articles published in a diversity of journals providing information about genes, proteins, pathways, and diseases. Each article investigates subsets of a biological process, but to gain insight into the functioning of a system as a whole, we must integrate information from multiple publications. Particularly, unraveling relationships between extra-cellular inputs and downstream molecular response mechanisms requires integrating conclusions from diverse publications. METHODOLOGY: We present an automated approach to biological knowledge discovery from PubMed abstracts, suitable for "connecting the dots" across the literature. We describe a storytelling algorithm that, given a start and end publication, typically with little or no overlap in content, identifies a chain of intermediate publications from one to the other, such that neighboring publications have significant content similarity. The quality of discovered stories is measured using local criteria such as the size of supporting neighborhoods for each link and the strength of individual links connecting publications, as well as global metrics of dispersion. To ensure that the story stays coherent as it meanders from one publication to another, we demonstrate the design of novel coherence and overlap filters for use as post-processing steps. CONCLUSIONS: WE DEMONSTRATE THE APPLICATION OF OUR STORYTELLING ALGORITHM TO THREE CASE STUDIES: i a many-one study exploring relationships between multiple cellular inputs and a molecule responsible for cell-fate decisions, ii a many-many study exploring the relationships between multiple cytokines and multiple downstream transcription factors, and iii a one-to-one study to showcase the ability to recover a cancer related association, viz. the Warburg effect, from past literature. The storytelling pipeline helps narrow down a scientist's focus from several hundreds of thousands of relevant documents to only

  16. Connecting the Dots between PubMed Abstracts

    Science.gov (United States)

    Hossain, M. Shahriar; Gresock, Joseph; Edmonds, Yvette; Helm, Richard; Potts, Malcolm; Ramakrishnan, Naren

    2012-01-01

    Background There are now a multitude of articles published in a diversity of journals providing information about genes, proteins, pathways, and diseases. Each article investigates subsets of a biological process, but to gain insight into the functioning of a system as a whole, we must integrate information from multiple publications. Particularly, unraveling relationships between extra-cellular inputs and downstream molecular response mechanisms requires integrating conclusions from diverse publications. Methodology We present an automated approach to biological knowledge discovery from PubMed abstracts, suitable for “connecting the dots” across the literature. We describe a storytelling algorithm that, given a start and end publication, typically with little or no overlap in content, identifies a chain of intermediate publications from one to the other, such that neighboring publications have significant content similarity. The quality of discovered stories is measured using local criteria such as the size of supporting neighborhoods for each link and the strength of individual links connecting publications, as well as global metrics of dispersion. To ensure that the story stays coherent as it meanders from one publication to another, we demonstrate the design of novel coherence and overlap filters for use as post-processing steps. Conclusions We demonstrate the application of our storytelling algorithm to three case studies: i) a many-one study exploring relationships between multiple cellular inputs and a molecule responsible for cell-fate decisions, ii) a many-many study exploring the relationships between multiple cytokines and multiple downstream transcription factors, and iii) a one-to-one study to showcase the ability to recover a cancer related association, viz. the Warburg effect, from past literature. The storytelling pipeline helps narrow down a scientist's focus from several hundreds of thousands of relevant documents to only around a hundred

  17. Elevers oppfatning av lærers tilbakemeldingspraksis: om sammenheng mellom graden av VfL-praksis og elevenes opplevde nytte av lærers skriftlige tilbakemeldinger i skriftlig norsk

    Directory of Open Access Journals (Sweden)

    Harald Eriksen

    2017-11-01

    Full Text Available Formålet med denne studien var å undersøke elevers oppfatninger av norsklærerens tilbakemeldingspraksis i skriftlig norsk. På bakgrunn av omfattende internasjonal forskning innen feltet ‘Vurdering for læring’ (VfL er det i denne studien utviklet teoridrevne hypoteser som testes ved å analysere et datasett fra to videregående skoler. Hypotesene er at elevene oppfatter lærers tilbakemelding som mer nyttig hvis den 1 retter seg mot målet med opplæringen, 2 gir elevene informasjon via en forklaring eller instruks om hvordan de skal komme nærmere målet og 3 at lærer legger til rette for bruk av tilbakemeldingen. Strukturell likningsmodellering (SEM av resultater fra en spørreundersøkelse blant elever (N = 213 er brukt som metode til å estimere forholdet mellom de fire latente variablene kriterier, forklaring, bruk og nytte (avhengig variabel. SEM er brukt fordi metoden egner seg til å undersøke sammenhenger i komplekse datasett. Funn er at elevene oppfatter at hvis lærer forklarer hvordan de kan forbedre seg, er dette positivt statistisk assosiert med opplevd nytte. Et mer overraskende funn er at lærerens tilrettelegging for bruk av tilbakemeldinger ikke er signifikant assosiert med opplevd nytte. Resultatene blir diskutert i artikkelen.

  18. Forord til den danske udgave af bogen rådgivning og terapi med børn

    DEFF Research Database (Denmark)

    Kragh-Müller, Grethe

    2007-01-01

    En bog om rådgivning og terapi med børn med en integrativ indfaldsvinkel. Der tages udgangspunkt i forskellige teorier og metoder.......En bog om rådgivning og terapi med børn med en integrativ indfaldsvinkel. Der tages udgangspunkt i forskellige teorier og metoder....

  19. The Arabidopsis Mediator Complex Subunits MED16, MED14, and MED2 Regulate Mediator and RNA Polymerase II Recruitment to CBF-Responsive Cold-Regulated Genes[C][W][OPEN

    Science.gov (United States)

    Hemsley, Piers A.; Hurst, Charlotte H.; Kaliyadasa, Ewon; Lamb, Rebecca; Knight, Marc R.; De Cothi, Elizabeth A.; Steele, John F.; Knight, Heather

    2014-01-01

    The Mediator16 (MED16; formerly termed SENSITIVE TO FREEZING6 [SFR6]) subunit of the plant Mediator transcriptional coactivator complex regulates cold-responsive gene expression in Arabidopsis thaliana, acting downstream of the C-repeat binding factor (CBF) transcription factors to recruit the core Mediator complex to cold-regulated genes. Here, we use loss-of-function mutants to show that RNA polymerase II recruitment to CBF-responsive cold-regulated genes requires MED16, MED2, and MED14 subunits. Transcription of genes known to be regulated via CBFs binding to the C-repeat motif/drought-responsive element promoter motif requires all three Mediator subunits, as does cold acclimation–induced freezing tolerance. In addition, these three subunits are required for low temperature–induced expression of some other, but not all, cold-responsive genes, including genes that are not known targets of CBFs. Genes inducible by darkness also required MED16 but required a different combination of Mediator subunits for their expression than the genes induced by cold. Together, our data illustrate that plants control transcription of specific genes through the action of subsets of Mediator subunits; the specific combination defined by the nature of the stimulus but also by the identity of the gene induced. PMID:24415770

  20. Nogle nye og gamle begreber i organisationsteori og virksomhedsledelse

    DEFF Research Database (Denmark)

    Søndergaard, Mikael

    2006-01-01

    empowerment og boundary spanning. Sammen med andre komponenter i "Super Leadership" forsøges disse begreber forankret i klassisk ledelsesteori. Ved at knytte empowerment sammen med boundary spanning kan vi i praksis videreudvikle et centralt begreb: boundary spanning rollen....

  1. Werlauff's kommenterede aktieselskabslov

    DEFF Research Database (Denmark)

    Werlauff, Erik; Schaumburg-Müller, Peer

    Bogen kommenterer hver enkelt paragraf i den danske aktieselskabslov, herunder med henvisninger til praksis fra danske domstole, EF-domstolen, Erhvervsankenævnet mv samt med relevante henvisninger til dansk og udenlandsk retslitteratur....

  2. Fabric formwork

    DEFF Research Database (Denmark)

    Manelius, Anne-Mette

    2012-01-01

    med metoder for arkitektonisk eksperimenterende praksis (research through design) med inspiration fra eksperimenterende forsknings- og undervisningspraksis indenfor tekstilforskalling i Canada og Skotland. Metoden kobles til en anvendelsesorienteret kontekst i form af erhvervsPhD-projektets forankring...

  3. Landskabskarakterkortlægning i praksis

    DEFF Research Database (Denmark)

    Hansen, Sol Strømbo; Olafsson, Anton Stahl; Caspersen, Ole H.

    2010-01-01

    Ringsted Kommune har igangsat og delvist implementret landskabskarakterkortlægning i planlægningen og i administrationen. Dette Videnblad bringer eksempler på anvendelse af metodens resultater som input til kommuneplanarbejdet. Dette beskrives, hvordan kortlægningen er implementret i kommuneplane...

  4. Den sociale praksis omkring arbejdsmiljø

    DEFF Research Database (Denmark)

    Kamp, Annette

    parties. This is a result of regulations during several years. However, this model is questioned and new principles for self-regulation, in form of ISO inspired management systems, are promoted. In this thesis a theoretical framework is developed in order to understand problems inherent in the existing......Management of the work environment - a political and culturel perspectiveFor many years activities to improve working environment at local enterprise level in Denmark and other Scandinavian countries have been carried out in the framework of institutionalized cooperation between the industrial...... model, and to understand the ambiguous outcomes of the application of new principles at enterprise level.The thesis take departure in theoretical contributions, which regard political processes as important for the understanding of organizations. The aim is to develop and consolidate this approach...

  5. Udvikling af sygeplejestuderendes informationskompetence i klinisk praksis

    DEFF Research Database (Denmark)

    Bønløkke, Mette; Kobow, Else; Trangbæk, Anne

    2008-01-01

    investigation based on focus group interviews with students and clinical educators. Results: It is important to define the roles of the students, clinical educators, librarians, and lecturers respectively during student supervision concerning assignments on nursing development and information. The students...

  6. Kultur, læring og praksis

    DEFF Research Database (Denmark)

    Jensen, Annie Aarup; Jæger, Kirsten

    2009-01-01

    Ariklen baserer sig på forskningsprojektet "Læreprocesser i multikulturelle kontekster" og unersøger på den baggrund, om Etienne Wengers teori om praksisfællesskaber kan anvendes til at belyse konkrete lære- og forandringsprocesser i samarbejdsrelationer mellem kulturelt forskellige medarbejdere,...

  7. Planning and scheduling algorithms for the COSMO-SkyMed constellation

    NARCIS (Netherlands)

    Bianchessi, Nicola; Righini, Giovanni

    2008-01-01

    The COSMO-SkyMed satellite constellation for the observation of the Earth is made of four satellites equipped with radar instruments and is intended for dual use, i.e. for security as well as for environmental monitoring purpose. The planning and scheduling problem for the COSMO-SkyMed constellation

  8. Health informatics research in Australia: retrospective analysis using PubMed

    Directory of Open Access Journals (Sweden)

    Kumara Mendis

    2007-01-01

    Discussion Australian HI publications in PubMed increased consistently throughout the period 1970-2005, which is on a par with world trends in HI publications. In Australia, most HI publications are in general medical journals. Lack of consistency in author names and failure to include the country name and even the state are the main obstacles to PubMed bibliometric analysis.

  9. En integrativ terapeutisk anvendelse af sang med udgangspunkt i neuropsykologiske, psykofysiologiske og psykodynamiske teorier

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner

    2007-01-01

    Hvordan kan terapeutiske forløb tilrettelægges så klienter med svære neurologiske forstyrrelser, fx mennesker med en demenssygdom, kan opnå en form for indsigt og terapeutisk forandring? Dette spørgsmål søges besvaret ved at beskrive anvendelsen af sang i den terapeutiske relation ud fra neuropsy...

  10. Fra interne udviklingsplaner til åben innovation med brug af Web 2.0 teknologi

    DEFF Research Database (Denmark)

    Scupola, Ada; Sørensen, Flemming; Nicolajsen, Hanne Westh

    Abstrakt: Artiklen handler om brugerinddragelse i service innovation. Der er fokus på idéfasen kombineret med anvendelse af kommunikationsteknologi og i særdeleshed webblogmediet. Behov som kreativitet, heterogenitet, engagement med mere diskuteres. Der afrapporteres fra et eksperiment på Roskild...

  11. Mediator MED23 regulates basal transcription in vivo via an interaction with P-TEFb.

    Science.gov (United States)

    Wang, Wei; Yao, Xiao; Huang, Yan; Hu, Xiangming; Liu, Runzhong; Hou, Dongming; Chen, Ruichuan; Wang, Gang

    2013-01-01

    The Mediator is a multi-subunit complex that transduces regulatory information from transcription regulators to the RNA polymerase II apparatus. Growing evidence suggests that Mediator plays roles in multiple stages of eukaryotic transcription, including elongation. However, the detailed mechanism by which Mediator regulates elongation remains elusive. In this study, we demonstrate that Mediator MED23 subunit controls a basal level of transcription by recruiting elongation factor P-TEFb, via an interaction with its CDK9 subunit. The mRNA level of Egr1, a MED23-controlled model gene, is reduced 4-5 fold in Med23 (-/-) ES cells under an unstimulated condition, but Med23-deficiency does not alter the occupancies of RNAP II, GTFs, Mediator complex, or activator ELK1 at the Egr1 promoter. Instead, Med23 depletion results in a significant decrease in P-TEFb and RNAP II (Ser2P) binding at the coding region, but no changes for several other elongation regulators, such as DSIF and NELF. ChIP-seq revealed that Med23-deficiency partially reduced the P-TEFb occupancy at a set of MED23-regulated gene promoters. Further, we demonstrate that MED23 interacts with CDK9 in vivo and in vitro. Collectively, these results provide the mechanistic insight into how Mediator promotes RNAP II into transcription elongation.

  12. The Contrasting Role of the Mediator Subunit MED30 in the Progression of Bladder Cancer.

    Science.gov (United States)

    Syring, Isabella; Weiten, Richard; Müller, Tim; Schmidt, Doris; Steiner, Susanne; Kristiansen, Glen; Müller, Stefan C; Ellinger, Jörg

    2017-12-01

    The Mediator complex is a key regulator of gene transcription, and several studies have demonstrated altered expression of particular subunits in diverse human diseases, especially cancer. To date, nothing is known about the role of MED30 in bladder cancer. We, therefore, performed an RNA expression and survival analysis of the subunit MED30 in 537 samples of bladder cancer by using the database cBioPortal. To validate these data on the protein level, we practiced immunohistochemical staining against MED30 on a tissue microarray containing 210 samples of all tumour stages and performed survival analyses. For functional analysis, the siRNA-mediated knockdown of MED30 was performed in the cell lines T24 and TCCSUP followed by proliferation, migration, and invasion assays. On the mRNA and protein levels, higher expression of MED30 is associated with better patient survival. In accordance with this, advanced T- and N-stages showed lower expression of MED30. In contrast, knockdown of MED30 led to reduction of the tumour parameters proliferation, migration, and invasion in the BCa cell lines. MED30 appears to be integrated in the progression of the urothelial tumour in the bladder. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  13. Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma.

    Science.gov (United States)

    Lim, Weng Khong; Ong, Choon Kiat; Tan, Jing; Thike, Aye Aye; Ng, Cedric Chuan Young; Rajasegaran, Vikneswari; Myint, Swe Swe; Nagarajan, Sanjanaa; Nasir, Nur Diyana Md; McPherson, John R; Cutcutache, Ioana; Poore, Gregory; Tay, Su Ting; Ooi, Wei Siong; Tan, Veronique Kiak Mien; Hartman, Mikael; Ong, Kong Wee; Tan, Benita K T; Rozen, Steven G; Tan, Puay Hoon; Tan, Patrick; Teh, Bin Tean

    2014-08-01

    Fibroadenomas are the most common breast tumors in women under 30 (refs. 1,2). Exome sequencing of eight fibroadenomas with matching whole-blood samples revealed recurrent somatic mutations solely in MED12, which encodes a Mediator complex subunit. Targeted sequencing of an additional 90 fibroadenomas confirmed highly frequent MED12 exon 2 mutations (58/98, 59%) that are probably somatic, with 71% of mutations occurring in codon 44. Using laser capture microdissection, we show that MED12 fibroadenoma mutations are present in stromal but not epithelial mammary cells. Expression profiling of MED12-mutated and wild-type fibroadenomas revealed that MED12 mutations are associated with dysregulated estrogen signaling and extracellular matrix organization. The fibroadenoma MED12 mutation spectrum is nearly identical to that of previously reported MED12 lesions in uterine leiomyoma but not those of other tumors. Benign tumors of the breast and uterus, both of which are key target tissues of estrogen, may thus share a common genetic basis underpinned by highly frequent and specific MED12 mutations.

  14. Obamas opgør med Bush låser ham i dronekrig

    DEFF Research Database (Denmark)

    Ulrich, Philip Christian

    2013-01-01

    En helt central del af Obamas valgkamp i 2008 var et opgør med dele af Bush administrationens krig mod terror. Obama er dog blevet fanget i en kontroversiel dronepolitik på grund af hans manglende succes med de indenrigspolitiske aspekter af opgøret...

  15. A novel mutation in MED12 causes FG syndrome (Opitz-Kaveggia syndrome)

    NARCIS (Netherlands)

    Rump, P.; Niessen, R. C.; Verbruggen, K. T.; Brouwer, O. F.; de Raad, M.; Hordijk, R.

    Opitz-Kaveggia syndrome is a rare X-linked multiple congenital anomalies and intellectual disability disorder caused by the recurrent p.R961W mutation in the MED12 gene. Twenty-three affected males from 10 families with this mutation in the MED12 gene have been described so far. Here we report on a

  16. Validation of search filters for identifying pediatric studies in PubMed

    NARCIS (Netherlands)

    Leclercq, Edith; Leeflang, Mariska M. G.; van Dalen, Elvira C.; Kremer, Leontien C. M.

    2013-01-01

    To identify and validate PubMed search filters for retrieving studies including children and to develop a new pediatric search filter for PubMed. We developed 2 different datasets of studies to evaluate the performance of the identified pediatric search filters, expressed in terms of sensitivity,

  17. Food-Dependent Exercise-Induced Anaphylaxis - Kasuistik med hydrolyseret valleprotein

    DEFF Research Database (Denmark)

    Junker Christensen, Morten

    2013-01-01

    Formål / Introduktion: Patienter med Food-Dependent Exercise-Induced Anaphylaxis (FDEIA) eller løbershock kan udvikle livstruende allergiske reaktioner (anafylaksi), når de kombinere fysisk anstrengelse med samtidig indtagelse af et normalt tolereret fødeemne - oftest hvede. Hydrolysering af prot...

  18. Die EBM-Datenbank DynaMed für PocketPC und Palm

    Directory of Open Access Journals (Sweden)

    Dollfuß, Helmut

    2007-09-01

    Full Text Available DynaMed is a database for Evidence Based Medicine. Licencee can download a stand-alone version of this database onto their Personal Digital Assistant (PDA. Contents and aims of DynaMed will be introduced. Main features of the PDA-version will be presented and illustrated with screenshots.

  19. Bør det være strafbart at have sex med dyr?

    DEFF Research Database (Denmark)

    Christiansen, Stine Billeschou; Greve, Vagn; Sandøe, Peter

    2009-01-01

    Artiklen opridser baggrunden for den standende diskussion om, hvorvidt der i Danmark bør være et generelt og absolut forbud mod menneskers seksuelle omgang med dyr. Indledningsvis gives et historisk overblik over udviklingen i den danske regulering af menneskers seksuelle omgang med dyr. Efterføl...

  20. Enabling multi-level relevance feedback on PubMed by integrating rank learning into DBMS.

    Science.gov (United States)

    Yu, Hwanjo; Kim, Taehoon; Oh, Jinoh; Ko, Ilhwan; Kim, Sungchul; Han, Wook-Shin

    2010-04-16

    Finding relevant articles from PubMed is challenging because it is hard to express the user's specific intention in the given query interface, and a keyword query typically retrieves a large number of results. Researchers have applied machine learning techniques to find relevant articles by ranking the articles according to the learned relevance function. However, the process of learning and ranking is usually done offline without integrated with the keyword queries, and the users have to provide a large amount of training documents to get a reasonable learning accuracy. This paper proposes a novel multi-level relevance feedback system for PubMed, called RefMed, which supports both ad-hoc keyword queries and a multi-level relevance feedback in real time on PubMed. RefMed supports a multi-level relevance feedback by using the RankSVM as the learning method, and thus it achieves higher accuracy with less feedback. RefMed "tightly" integrates the RankSVM into RDBMS to support both keyword queries and the multi-level relevance feedback in real time; the tight coupling of the RankSVM and DBMS substantially improves the processing time. An efficient parameter selection method for the RankSVM is also proposed, which tunes the RankSVM parameter without performing validation. Thereby, RefMed achieves a high learning accuracy in real time without performing a validation process. RefMed is accessible at http://dm.postech.ac.kr/refmed. RefMed is the first multi-level relevance feedback system for PubMed, which achieves a high accuracy with less feedback. It effectively learns an accurate relevance function from the user's feedback and efficiently processes the function to return relevant articles in real time.

  1. A study on PubMed search tag usage pattern: association rule mining of a full-day PubMed query log.

    Science.gov (United States)

    Mosa, Abu Saleh Mohammad; Yoo, Illhoi

    2013-01-09

    The practice of evidence-based medicine requires efficient biomedical literature search such as PubMed/MEDLINE. Retrieval performance relies highly on the efficient use of search field tags. The purpose of this study was to analyze PubMed log data in order to understand the usage pattern of search tags by the end user in PubMed/MEDLINE search. A PubMed query log file was obtained from the National Library of Medicine containing anonymous user identification, timestamp, and query text. Inconsistent records were removed from the dataset and the search tags were extracted from the query texts. A total of 2,917,159 queries were selected for this study issued by a total of 613,061 users. The analysis of frequent co-occurrences and usage patterns of the search tags was conducted using an association mining algorithm. The percentage of search tag usage was low (11.38% of the total queries) and only 2.95% of queries contained two or more tags. Three out of four users used no search tag and about two-third of them issued less than four queries. Among the queries containing at least one tagged search term, the average number of search tags was almost half of the number of total search terms. Navigational search tags are more frequently used than informational search tags. While no strong association was observed between informational and navigational tags, six (out of 19) informational tags and six (out of 29) navigational tags showed strong associations in PubMed searches. The low percentage of search tag usage implies that PubMed/MEDLINE users do not utilize the features of PubMed/MEDLINE widely or they are not aware of such features or solely depend on the high recall focused query translation by the PubMed's Automatic Term Mapping. The users need further education and interactive search application for effective use of the search tags in order to fulfill their biomedical information needs from PubMed/MEDLINE.

  2. The MedAustron project: an example of large-scale technology transfer

    CERN Multimedia

    Antonella Del Rosso & Michael Benedikt

    2013-01-01

    In January this year, CERN’s Director-General Rolf Heuer handed over the first ion source to the MedAustron therapy centre in the town of Wiener Neustadt in the presence of the Austrian authorities. This milestone marks the beginning of the transition from the development and design phase to the commissioning of the new facility.   Handover of the ion source to MedAustron on 11 January, 2013. From left to right: Michael Benedikt (Project Leader MedAustron at CERN), Karlheinz Töchterle (Austrian Federal Minister of Science and Research), Erwin Pröll (Governor of Lower Austria), Rolf Heuer (Director-General CERN), Klaus Schneeberger (Lower Austrian State Parliament, Head of EBG MedAustron Council). The goal of the MedAustron project is the construction of an ion-therapy and research centre, based on a synchrotron accelerator complex, in Austria (for more about the technical part of the MedAustron project, click here). “MedAustron will be the first large-sca...

  3. Quantity and quality assessment of randomized controlled trials on orthodontic practice in PubMed.

    Science.gov (United States)

    Shimada, Tatsuo; Takayama, Hisako; Nakamura, Yoshiki

    2010-07-01

    To find current high-quality evidence for orthodontic practice within a reasonable time, we tested the performance of a PubMed search. PubMed was searched using publication type randomized controlled trial and medical subject heading term "orthodontics" for articles published between 2003 and 2007. The PubMed search results were compared with those from a hand search of four orthodontic journals to determine the sensitivity of PubMed search. We evaluated the precision of the PubMed search result and assessed the quality of individual randomized controlled trials using the Jadad scale. Sensitivity and precision were 97.46% and 58.12%, respectively. In PubMed, of the 277 articles retrieved, 161 (58.12%) were randomized controlled trials on orthodontic practice, and 115 of the 161 articles (71.42%) were published in four orthodontic journals: American Journal of Orthodontics and Dentofacial Orthopedics, The Angle Orthodontist, the European Journal of Orthodontics, and the Journal of Orthodontics. Assessment by the Jadad scale revealed 60 high-quality randomized controlled trials on orthodontic practice, of which 45 (75%) were published in these four journals. PubMed is a highly desirable search engine for evidence-based orthodontic practice. To stay current and get high-quality evidence, it is reasonable to look through four orthodontic journals: American Journal of Orthodontics and Dentofacial Orthopedics, The Angle Orthodontist, the European Journal of Orthodontics, and the Journal of Orthodontics.

  4. Silencing SlMED18, tomato Mediator subunit 18 gene, restricts internode elongation and leaf expansion.

    Science.gov (United States)

    Wang, Yunshu; Hu, Zongli; Zhang, Jianling; Yu, XiaoHui; Guo, Jun-E; Liang, Honglian; Liao, Changguang; Chen, Guoping

    2018-02-19

    Mediator complex, a conserved multi-protein, is necessary for controlling RNA polymerase II (Pol II) transcription in eukaryotes. Given little is known about them in tomato, a tomato Mediator subunit 18 gene was isolated and named SlMED18. To further explore the function of SlMED18, the transgenic tomato plants targeting SlMED18 by RNAi-mediated gene silencing were generated. The SlMED18-RNAi lines exhibited multiple developmental defects, including smaller size and slower growth rate of plant and significantly smaller compound leaves. The contents of endogenous bioactive GA 3 in SlMED18 silenced lines were slightly less than that in wild type. Furthermore, qRT-PCR analysis indicated that expression of gibberellins biosynthesis genes such as SlGACPS and SlGA20x2, auxin transport genes (PIN1, PIN4, LAX1 and LAX2) and several key regulators, KNOX1, KNOX2, PHAN and LANCEOLATE(LA), which involved in the leaf morphogenesis were significantly down-regulated in SlMED18-RNAi lines. These results illustrated that SlMED18 plays an essential role in regulating plant internode elongation and leaf expansion in tomato plants and it acts as a key positive regulator of gibberellins biosynthesis and signal transduction as well as auxin proper transport signalling. These findings are the basis for understanding the function of the individual Mediator subunits in tomato.

  5. A functional portrait of Med7 and the mediator complex in Candida albicans.

    Science.gov (United States)

    Tebbji, Faiza; Chen, Yaolin; Richard Albert, Julien; Gunsalus, Kearney T W; Kumamoto, Carol A; Nantel, André; Sellam, Adnane; Whiteway, Malcolm

    2014-11-01

    Mediator is a multi-subunit protein complex that regulates gene expression in eukaryotes by integrating physiological and developmental signals and transmitting them to the general RNA polymerase II machinery. We examined, in the fungal pathogen Candida albicans, a set of conditional alleles of genes encoding Mediator subunits of the head, middle, and tail modules that were found to be essential in the related ascomycete Saccharomyces cerevisiae. Intriguingly, while the Med4, 8, 10, 11, 14, 17, 21 and 22 subunits were essential in both fungi, the structurally highly conserved Med7 subunit was apparently non-essential in C. albicans. While loss of CaMed7 did not lead to loss of viability under normal growth conditions, it dramatically influenced the pathogen's ability to grow in different carbon sources, to form hyphae and biofilms, and to colonize the gastrointestinal tracts of mice. We used epitope tagging and location profiling of the Med7 subunit to examine the distribution of the DNA sites bound by Mediator during growth in either the yeast or the hyphal form, two distinct morphologies characterized by different transcription profiles. We observed a core set of 200 genes bound by Med7 under both conditions; this core set is expanded moderately during yeast growth, but is expanded considerably during hyphal growth, supporting the idea that Mediator binding correlates with changes in transcriptional activity and that this binding is condition specific. Med7 bound not only in the promoter regions of active genes but also within coding regions and at the 3' ends of genes. By combining genome-wide location profiling, expression analyses and phenotyping, we have identified different Med7p-influenced regulons including genes related to glycolysis and the Filamentous Growth Regulator family. In the absence of Med7, the ribosomal regulon is de-repressed, suggesting Med7 is involved in central aspects of growth control.

  6. A synergetic hybridization of adsorption cycle with the multi-effect distillation (MED)

    KAUST Repository

    Thu, K.

    2014-01-01

    Multi-effect distillation (MED) systems are proven and energy efficient thermally-driven desalination systems for handling harsh seawater feed in the Gulf region. The high cycle efficiency is markedly achieved by latent energy re-use with minimal stage temperature-difference across the condensing steam and the evaporating saline seawater in each stage. The efficacies of MED system are (i) its low stage-temperature-difference between top brine temperature (TBT) and final condensing temperature, (ii) its robustness to varying salinity and ability to handle harmful algae Blooming (HABs) and (iii) its compact foot-print per unit water output. The practical TBT of MED systems, hitherto, is around 65 C for controllable scaling and fouling with the ambient-limited final condenser temperature, usually from 30 to 45 C. The adsorption (ADC) cycles utilize low-temperature heat sources (typically below 90 C) to produce useful cooling power and potable water. Hybridizing MED with AD cycles, they synergistically improve the water production rates at the same energy input whilst the AD cycle is driven by the recovered waste heat. We present a practical AD + MED combination that can be retrofitted to existing MEDs: The cooling energy of AD cycle through the water vapor uptake by the adsorbent is recycled internally, providing lower temperature condensing environment in the effects whilst the final condensing temperature of MED is as low as 5-10 C, which is below ambient. The increase in the temperature difference between TBT and final condensing temperature accommodates additional MED stages. A detailed numerical model is presented to capture the transient behaviors of heat and mass interactions in the combined AD + MED cycles and the results are presented in terms of key variables. It is observed that the water production rates of the combined cycle increase to give a GOR of 8.8 from an initial value of 5.9. © 2013 Elsevier Ltd. All rights reserved.

  7. Vekst, metabolisme og ølbrygging med melkesyrebakterier og gjær

    OpenAIRE

    Kvam, Guro

    2017-01-01

    Ølbrygging er et håndverk forbundet med lange tradisjoner, med røtter tilbake til det 12. århundrets Europa. Før dagens mikrobiologiske teknikker ble oppfunnet var all øl spontangjæret med en kompleks sammensetning av ulike gjær- og bakteriestammer. I dag produseres fremdeles enkelte av disse ølsortene under navn som lambic, geuze eller Berliner weisse, og interessen for slike ølsorter har økt betraktelig de siste årene. Mange bryggerier benytter i dag kjente kulturer av gjær og melkesyrebakt...

  8. Differential expression of Mediator complex subunit MED15 in testicular germ cell tumors.

    Science.gov (United States)

    Klümper, Niklas; Syring, Isabella; Offermann, Anne; Shaikhibrahim, Zaki; Vogel, Wenzel; Müller, Stefan C; Ellinger, Jörg; Strauß, Arne; Radzun, Heinz Joachim; Ströbel, Philipp; Brägelmann, Johannes; Perner, Sven; Bremmer, Felix

    2015-09-17

    Testicular germ cell tumors (TGCT) are the most common cancer entities in young men with increasing incidence observed in the last decades. For therapeutic management it is important, that TGCT are divided into several histological subtypes. MED15 is part of the multiprotein Mediator complex which presents an integrative hub for transcriptional regulation and is known to be deregulated in several malignancies, such as prostate cancer and bladder cancer role, whereas the role of the Mediator complex in TGCT has not been investigated so far. Aim of the study was to investigate the implication of MED15 in TGCT development and its stratification into histological subtypes. Immunohistochemical staining (IHC) against Mediator complex subunit MED15 was conducted on a TGCT cohort containing tumor-free testis (n = 35), intratubular germ cell neoplasia unclassified (IGCNU, n = 14), seminomas (SEM, n = 107) and non-seminomatous germ cell tumors (NSGCT, n = 42), further subdivided into embryonic carcinomas (EC, n = 30), yolk sac tumors (YST, n = 5), chorionic carcinomas (CC, n = 5) and teratomas (TER, n = 2). Quantification of MED15 protein expression was performed through IHC followed by semi-quantitative image analysis using the Definiens software. In tumor-free seminiferous tubules, MED15 protein expression was absent or only low expressed in spermatogonia. Interestingly, the precursor lesions IGCNU exhibited heterogeneous but partly very strong MED15 expression. SEM weakly express the Mediator complex subunit MED15, whereas NSGCT and especially EC show significantly enhanced expression compared to tumor-free testis. In conclusion, MED15 is differentially expressed in tumor-free testis and TGCT. While MED15 is absent or low in tumor-free testis and SEM, NSGCT highly express MED15, hinting at the diagnostic potential of this marker to distinguish between SEM and NSGCT. Further, the precursor lesion IGCNU showed increased nuclear MED15

  9. Leaving the Lecture Behind: Putting PubMed Instruction into the Hands of the Students.

    Science.gov (United States)

    Turner, Rose L; M Ketchum, Andrea; Ratajeski, Melissa A; Wessel, Charles B

    2017-01-01

    This column describes the development of a one-shot PubMed instruction class for medical students at a health sciences library. Background information on the objective is presented and discussed in the context of educational practice literature. The new course design centers on a guided group method of instruction in order to integrate more active learning. Surveyed students reported that the method was an effective way to learn how to search PubMed and that they preferred it to a traditional lecture. Pros and cons of the method are offered for other health sciences libraries interested in presenting PubMed instruction in a similar manner.

  10. Sjuksköterskors upplevelse vid vård av patienter med substansbrukssyndrom

    OpenAIRE

    Hanna, Johansson; Frida, Zetterman

    2016-01-01

    Bakgrund Tidigare forskning visar att sjuksköterskor har förutfattade meningar om patienter med en stigmatiserande diagnos. Sjuksköterskor stigmatiserar och har negativa attityder som påverkar deras vård av dessa patienter. Individer med substansbrukssyndrom är en grupp som är särskilt utsatt för stigmatisering i samhället. Dessa individer påträffas inom samtliga specialiteter inom vården. Denna studie fokuserar därför på sjuksköterskors upplevelse av patienter med substansbrukssyndrom. Syfte...

  11. Genre and categorization

    DEFF Research Database (Denmark)

    Ulbæk, Ib

    2015-01-01

    Artiklen undersøger forholdet mellem genre-kategorien og sætter den i forbindelse med andre former for kategorisering med henblik på at afklare om genrebegrebet har en særstatus eller om sprogbrugeren kan udnytte sin almene kategorividen til at forstå tekster....

  12. Brug af alternativ isolering i forbindelse med renovering af ældre etageejendomme

    DEFF Research Database (Denmark)

    Hansen, Ernst Jan de Place

    2003-01-01

    Resume af rapport om praktiske erfaringer med brug af alternative isoleringsmaterialer i en renoveringsopgave, udarbejdet af Byfornyelse København m.fl. under Energistyrelsens udviklingsprogram "Miljø- og arbejdsmiljøvenlig isolering"...

  13. MedWatch, the FDA Safety Information and Adverse Event Reporting Program

    Science.gov (United States)

    ... Reporting Program MedWatch: The FDA Safety Information and Adverse Event Reporting Program Share Tweet Linkedin Pin it ... approved information that can help patients avoid serious adverse events. Potential Signals of Serious Risks/New Safety ...

  14. Ma et al., Afr J Tradit Complement Altern Med. (2016) 13(3):197-202 ...

    African Journals Online (AJOL)

    Background: Sulfur fumigation is one of the processing methods of Chinese medicinal ... them, the contents of 23 compounds in sulfur-fumigated Dangshen were much lower than that in air-dried Dangshen, such as ..... Asia-Pacific Tradit. Med.

  15. A synergetic hybridization of adsorption cycle with the multi-effect distillation (MED)

    KAUST Repository

    Thu, K.; Kim, Youngdeuk; Amy, Gary L.; Chun, Wongee; Ng, Kim Choon

    2014-01-01

    Multi-effect distillation (MED) systems are proven and energy efficient thermally-driven desalination systems for handling harsh seawater feed in the Gulf region. The high cycle efficiency is markedly achieved by latent energy re-use with minimal

  16. Reconstitution of active human core Mediator complex reveals a pivotal role of the MED14 subunit

    Science.gov (United States)

    Cevher, Murat A.; Shi, Yi; Li, Dan; Chait, Brian T.; Malik, Sohail; Roeder, Robert G.

    2014-01-01

    The evolutionarily conserved Mediator complex is a critical coactivator for RNA polymerase II (Pol II)-mediated transcription. Here, we report the reconstitution of a functional 15-subunit human core Mediator complex and its characterization by functional assays and chemical cross-linking coupled to mass spectrometry (CX-MS). Whereas the reconstituted head and middle modules can stably associate, only with incorporation of MED14 into the bi-modular complex does it acquire basal and coactivator functions. This results from a dramatically enhanced ability of MED14-containing complexes to associate with Pol II. Altogether, our analyses identify MED14 as both an architectural and a functional backbone of the Mediator complex. We further establish a conditional requirement for metazoan-specific MED26 that becomes evident in the presence of heterologous nuclear factors. This general approach paves the way for systematically dissecting the multiple layers of functionalities associated with the Mediator complex. PMID:25383669

  17. Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit.

    Science.gov (United States)

    Cevher, Murat A; Shi, Yi; Li, Dan; Chait, Brian T; Malik, Sohail; Roeder, Robert G

    2014-12-01

    The evolutionarily conserved Mediator complex is a critical coactivator for RNA polymerase II (Pol II)-mediated transcription. Here we report the reconstitution of a functional 15-subunit human core Mediator complex and its characterization by functional assays and chemical cross-linking coupled to MS (CX-MS). Whereas the reconstituted head and middle modules can stably associate, basal and coactivator functions are acquired only after incorporation of MED14 into the bimodular complex. This results from a dramatically enhanced ability of MED14-containing complexes to associate with Pol II. Altogether, our analyses identify MED14 as both an architectural and a functional backbone of the Mediator complex. We further establish a conditional requirement for metazoan-specific MED26 that becomes evident in the presence of heterologous nuclear factors. This general approach paves the way for systematic dissection of the multiple layers of functionality associated with the Mediator complex.

  18. Ainooson et al., Afr J Tradit Complement Altern Med. (2012) 9(1):8 ...

    African Journals Online (AJOL)

    AJTCAM

    Ainooson et al., Afr J Tradit Complement Altern Med. (2012) ..... The authors are grateful for the technical assistance offered by Messrs Thomas Ansah, Gordon Darku and George Ofei of ... Miller, J. R. (2003). ... R. Watson and V. R. Preedy.

  19. [Use of PubMed to improve evidence-based medicine in routine urological practice].

    Science.gov (United States)

    Rink, M; Kluth, L A; Shariat, S F; Chun, F K; Fisch, M; Dahm, P

    2013-03-01

    Applying evidence-based medicine in daily clinical practice is the basis of patient-centered medicine and knowledge of accurate literature acquisition skills is necessary for informed clinical decision-making. PubMed is an easy accessible, free bibliographic database comprising over 21 million citations from the medical field, life-science journals and online books. The article summarizes the effective use of PubMed in routine urological clinical practice based on a common case scenario. This article explains the simple use of PubMed to obtain the best search results with the highest evidence. Accurate knowledge about the use of PubMed in routine clinical practice can improve evidence-based medicine and also patient treatment.

  20. Orientering og banelægning med Google Earth og Condes

    DEFF Research Database (Denmark)

    Jørgensen, Henrik Taarsted; Piaster, Thomas Gabriel

    2011-01-01

    Et e-læringsmodul på Danmarks undervisningsportal, som handler om hvordan man kan arbejde med banelægning indenfor o-løb. Med udgangspunkt i de to gratisprogrammer Google Earth og Condes lærer man gennem modulet, hvordan man indtegner poster og hvordan eleverne kan gøre det samme.......Et e-læringsmodul på Danmarks undervisningsportal, som handler om hvordan man kan arbejde med banelægning indenfor o-løb. Med udgangspunkt i de to gratisprogrammer Google Earth og Condes lærer man gennem modulet, hvordan man indtegner poster og hvordan eleverne kan gøre det samme....

  1. PubMedPortable: A Framework for Supporting the Development of Text Mining Applications.

    Science.gov (United States)

    Döring, Kersten; Grüning, Björn A; Telukunta, Kiran K; Thomas, Philippe; Günther, Stefan

    2016-01-01

    Information extraction from biomedical literature is continuously growing in scope and importance. Many tools exist that perform named entity recognition, e.g. of proteins, chemical compounds, and diseases. Furthermore, several approaches deal with the extraction of relations between identified entities. The BioCreative community supports these developments with yearly open challenges, which led to a standardised XML text annotation format called BioC. PubMed provides access to the largest open biomedical literature repository, but there is no unified way of connecting its data to natural language processing tools. Therefore, an appropriate data environment is needed as a basis to combine different software solutions and to develop customised text mining applications. PubMedPortable builds a relational database and a full text index on PubMed citations. It can be applied either to the complete PubMed data set or an arbitrary subset of downloaded PubMed XML files. The software provides the infrastructure to combine stand-alone applications by exporting different data formats, e.g. BioC. The presented workflows show how to use PubMedPortable to retrieve, store, and analyse a disease-specific data set. The provided use cases are well documented in the PubMedPortable wiki. The open-source software library is small, easy to use, and scalable to the user's system requirements. It is freely available for Linux on the web at https://github.com/KerstenDoering/PubMedPortable and for other operating systems as a virtual container. The approach was tested extensively and applied successfully in several projects.

  2. PubMed search filters for the study of putative outdoor air pollution determinants of disease

    OpenAIRE

    Curti, Stefania; Gori, Davide; Di Gregori, Valentina; Farioli, Andrea; Baldasseroni, Alberto; Fantini, Maria Pia; Christiani, David C; Violante, Francesco S; Mattioli, Stefano

    2016-01-01

    Objectives: Several PubMed search filters have been developed in contexts other than environmental. We aimed at identifying efficient PubMed search filters for the study of environmental determinants of diseases related to outdoor air pollution. Methods: We compiled a list of Medical Subject Headings (MeSH) and non-MeSH terms seeming pertinent to outdoor air pollutants exposure as determinants of diseases in the general population. We estimated proportions of potentially pertinent articles to...

  3. Use of scientific social networking to improve the research strategies of PubMed readers

    OpenAIRE

    Evdokimov, Pavel; Kudryavtsev, Alexey; Ilgisonis, Ekaterina; Ponomarenko, Elena; Lisitsa, Andrey

    2016-01-01

    Background Keeping up with journal articles on a daily basis is an important activity of scientists engaged in biomedical research. Usually, journal articles and papers in the field of biomedicine are accessed through the Medline/PubMed electronic library. In the process of navigating PubMed, researchers unknowingly generate user-specific reading profiles that can be shared within a social networking environment. This paper examines the structure of the social networking environment generated...

  4. Zavedanje pomembnosti vertikalnega komuniciranja med nadrejenimi in podrejenimi v podjetju in vpliv na (ne) uspeh podjetja

    OpenAIRE

    Bezjak, Mojca

    2017-01-01

    Vertikalno komuniciranje je dvosmerno komuniciranje - povraten proces.Predstavimo vertikalno komuniciranje med nadrejenimi in podrejenimi v podjetju in vpliv na uspeh podjetja.Predstavitev različnih vrst komuniciranja, vplivov komuniciranja na človeka. Opišemo povezanost vertikalnega komuniciranja,medsebojnih odnosov in uspeh podjetja. V empiričnem delu diplomskega projekta z odgovori na vprašanja, ki se navezujejo na vertikalno komuniciranje in medsebojne odnose med nadrejenimi in podrejenim...

  5. Kvalitative Interviews med D&I Censorer, Undervisere, Kandidater og Studerende

    DEFF Research Database (Denmark)

    Brodersen, Søsser; Lindegaard, Hanne

    2010-01-01

    Som en opfølgning på telefon surveys blev der i tredje fase af D&I evalueringen gennemført en række kvalitative interviews med udvalgte censorer, undervisere, kandidater og studerende. Formålet med de kvalitative interviews har været at undersøge om: - D&I studerende og kandidater gennem forløbet i...

  6. Use of scientific social networking to improve the research strategies of PubMed readers.

    Science.gov (United States)

    Evdokimov, Pavel; Kudryavtsev, Alexey; Ilgisonis, Ekaterina; Ponomarenko, Elena; Lisitsa, Andrey

    2016-02-18

    Keeping up with journal articles on a daily basis is an important activity of scientists engaged in biomedical research. Usually, journal articles and papers in the field of biomedicine are accessed through the Medline/PubMed electronic library. In the process of navigating PubMed, researchers unknowingly generate user-specific reading profiles that can be shared within a social networking environment. This paper examines the structure of the social networking environment generated by PubMed users. A web browser plugin was developed to map [in Medical Subject Headings (MeSH) terms] the reading patterns of individual PubMed users. We developed a scientific social network based on the personal research profiles of readers of biomedical articles. A browser plugin is used to record the digital object identifier or PubMed ID of web pages. Recorded items are posted on the activity feed and automatically mapped to PubMed abstract. Within the activity feed a user can trace back previously browsed articles and insert comments. By calculating the frequency with which specific MeSH occur, the research interests of PubMed users can be visually represented with a tag cloud. Finally, research profiles can be searched for matches between network users. A social networking environment was created using MeSH terms to map articles accessed through the Medline/PubMed online library system. In-network social communication is supported by the recommendation of articles and by matching users with similar scientific interests. The system is available at http://bioknol.org/en/.

  7. Murværk opmuret med vådmørtler

    DEFF Research Database (Denmark)

    Hansen, Klavs Feilberg

    Vådmørtler benyttes i størstedelen af det murede nybyggeri. Egenskaberne af murværk opmuret med vådmørtel er i dag kun mangelfuldt dokumenteret. Denne rapport beskriver en metode til bedre dokumentation af de styrkemæssige egenskaber ved murværk opmuret med vådmørtel. Første del af rapporten genn...

  8. Folkeskolens opgaver overfor børn med forskellig social, etnisk og kultur baggrund

    DEFF Research Database (Denmark)

    Tireli, Üzeyir

    2012-01-01

    Med udgangspukt i en case om romapige fremhæves det, at skolen og lærerne stigmatiserer elever med en anden baggrund end etnisk dansk. Det betyder, at skolen i fremtiden står overfor en stor ligestillingsopgave, da prognoser tyder på øget indvandring. Der kan derfor let opstår øgede forskelle mel...

  9. The performances of standard and ResMed masks during bag-valve-mask ventilation.

    Science.gov (United States)

    Lee, Hyoung Youn; Jeung, Kyung Woon; Lee, Byung Kook; Lee, Seung Joon; Jung, Yong Hun; Lee, Geo Sung; Min, Yong Il; Heo, Tag

    2013-01-01

    A tight mask seal is frequently difficult to obtain and maintain during single-rescuer bag-valve-mask (BVM) ventilation. The ResMed mask (Bella Vista, NSW, Australia) is a continuous-positive-airway-pressure mask (CM) designed for noninvasive ventilation. In this study, we compared the ventilation performances of a standard mask (SM) and a ResMed CM using a simulation manikin in an out-of-hospital single-rescuer BVM ventilation scenario. Thirty emergency medical technicians (EMTs) performed two 2-minute attempts to ventilate a simulation manikin using BVM ventilation, alternatively, with the SM or the ResMed CM in a randomized order. Ventilation parameters including tidal volume and peak airway pressure were measured using computer analysis software connected to the simulation manikin. Successful volume delivery was defined as delivery of 440-540 mL of tidal volume in accord with present cardiopulmonary resuscitation guidelines. BVM ventilation using the ResMed CM produced higher mean (± standard deviation) tidal volumes (452 ± 50 mL vs. 394 ± 113 mL, p = 0.014) and had a higher proportion of successful volume deliveries (65.3% vs. 26.7%, p < 0.001) than that using the SM. Peak airway pressure was higher in BVM ventilation using the ResMed CM (p = 0.035). Stomach insufflation did not occur during either method. Twenty-nine of the participants (96.7%) preferred BVM ventilation using the ResMed CM. BVM ventilations using ResMed CM resulted in a significantly higher proportion of successful volume deliveries meeting the currently recommended range of tidal volume. Clinical studies are needed to determine the value of the ResMed CM for BVM ventilation.

  10. The Web-based CanMEDS Resident Learning Portfolio Project (WEBCAM): how we got started.

    Science.gov (United States)

    Glen, Peter; Balaa, Fady; Momoli, Franco; Martin, Louise; Found, Dorothy; Arnaout, Angel

    2016-12-01

    The CanMEDS framework is ubiquitous in Canadian postgraduate medical education; however, training programs do not have a universal method of assessing competence. We set out to develop a novel portfolio that allowed trainees to generate a longitudinal record of their training and development within the framework. The portfolio provided an objective means for the residency program director to document and evaluate resident progress within the CanMEDS roles.

  11. 1 Driftsøkonomi med planlegging 2 Wild reindeer of the Soviet Union

    Directory of Open Access Journals (Sweden)

    Sven Skjenneberg

    1985-05-01

    Full Text Available Ansgar J. Kosmo. 1986. "Driftsøkonomi med planlegging". Reindriftsadministrasjonen, Alta. 111s. (Foreligger i januaer 1986. Utgis i samarbeid med Samisk utdanningsråd.E.E. Syroechovskij (ed.. 1984. "Wild reindeer of the Soviet Union". English version by U.S. Department of Interior and National Science Foundation. Lectures presented at a research conference at Dudinka, Taimyr in 1975. 43 lectures , some also with direct importance for the reindeer husbandry.

  12. Børn med ADHD skaber øget konflikt om morgenen

    DEFF Research Database (Denmark)

    Lange, Anne-Mette

    2017-01-01

    Dækning af ny forskning fra videnskabelige præsentationer på den femte Internationale ADHD Congress i Vancouver, 2017. http://propatienter.dk/sygdomme/psyken/280-born-med-adhd-skaber-oget-konflikt-om-morgenen.html......Dækning af ny forskning fra videnskabelige præsentationer på den femte Internationale ADHD Congress i Vancouver, 2017. http://propatienter.dk/sygdomme/psyken/280-born-med-adhd-skaber-oget-konflikt-om-morgenen.html...

  13. EU-retlige og forvaltningsretlige aspekter ved kommunernes tilsyn med taxiførere

    DEFF Research Database (Denmark)

    Sørensen, Henning Fuglsang

    2011-01-01

    Afhandlingen gennemgår taxilovens krav til kommunernes tilsyn med førere af taxier, herunder særligt de eu-retlige og forvaltningsretlige problemer i dette tilsyn.......Afhandlingen gennemgår taxilovens krav til kommunernes tilsyn med førere af taxier, herunder særligt de eu-retlige og forvaltningsretlige problemer i dette tilsyn....

  14. Afkølingstid - breddeopgaver 45-46 med didaktisk kommentar

    DEFF Research Database (Denmark)

    Jensen, Jens Højgaard

    2011-01-01

    Mit formål med artikelserien om breddeopgaver er – udover at gøre opmærksom på RUCs fysikuddannelse – dobbelt: Dels udvælger jeg opgaverne, så de kan have interesse som fysikproblemer i egen ret. Dels udvælger jeg dem med henblik på at kunne knytte didaktiske overvejelser til dem af interesse...

  15. Kvalitetscirkler – at arbejde med kvalitet uden at gå i stå

    DEFF Research Database (Denmark)

    Pedersen, Ulla

    2001-01-01

    Artiklen omhandler en metode, kvalitetscirkler, til kvalitetssikring og -udvikling. Metoden er udsprunget fra Demings teori og anvendes til bottom-up udvikling. Den er afprøvet i pilotprojekt i ergoterapien på Sønderborg Sygehus med succes.......Artiklen omhandler en metode, kvalitetscirkler, til kvalitetssikring og -udvikling. Metoden er udsprunget fra Demings teori og anvendes til bottom-up udvikling. Den er afprøvet i pilotprojekt i ergoterapien på Sønderborg Sygehus med succes....

  16. Susceptibility of MED-Q1 and MED-Q3 Biotypes of Bemisia tabaci (Hemiptera: Aleyrodidae) Populations to Essential and Seed Oils.

    Science.gov (United States)

    Samuel Fogné, Drabo; Olivier, Gnankine; Bassolé, Imael H N; Nébié, Roger Charles; Laurence, Mouton

    2017-06-01

    Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae) is a major pest of many agricultural and ornamental crops in tropical and subtropical regions causing damages that result in important economic losses. Insecticides are commonly used in greenhouses or fields to control B. tabaci populations leading to rapid evolution of resistance that render treatments inefficient. Therefore, and for environmental and human health concerns, other approaches must be developed for this pest management. In the present study, we compare, using the leaf dip method, the toxicity of three essential oils (Cymbopogon citratus, Ocimum americanum, and Hyptis spicigera) and three seed oils (Lannea microcarpa, Lannea acida, and Carapa procera) with three chemical insecticides (acetamiprid, deltamethrin, and chlorpyrifos-ethyl) on adults. Two B. tabaci biotypes (MED-Q1 and MED-Q3) belonging to the Mediterranean species and collected in Burkina Faso were used. Essential oils were analyzed by gas chromatography-mass spectrometry and gas chromatography-flame ionization detector. We showed that these two biotypes have different levels of resistance to the three insecticides, MED-Q3 being more sensitive than MED-Q1. Moreover, they differ in the frequency of resistance alleles to insecticides, especially for organophosphates, as these alleles are almost fixed in MED-Q1. On the other hand, the two biotypes prove to be more susceptible to the plant extracts than to insecticides except for chlorpyrifos-ethyl, with essential oils that showed the highest insecticidal activities. Monoterpenes content were the most abundant and showed the highest insecticidal activities. Our results indicated that essential oils, but also seed oils, have the potential to constitute an alternative strategy of pest management. © The Authors 2017. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  17. Tracking Australian health and medical research expenditure with a PubMed bibliometric method.

    Science.gov (United States)

    Mendis, Kumara; Bailey, Jannine; McLean, Rick

    2015-06-01

    To assess Australian health and medical research (HMR) investment returns by measuring the trends in HMR expenditure and PubMed publications by Australian authors. Bibliometric analysis collating Australian HMR expenditure reported by the Australian Institute of Health and Welfare and Australian HMR publications indexed in PubMed. Similar methods were applied to data from the United Kingdom and New Zealand. From financial year 2000/01 through 2011/12, HMR investment increased by 232% from $1.49 to $4.94 billion (current prices adjusted for inflation), while PubMed publications increased by 123% from 10,696 to 23,818. The average HMR investment required for a single PubMed publication rose by 49% from $139,304 in 2000/01 to $207,364 in 2011/12. Quality analyses showed an increase in systematic reviews, cohort studies and clinical trials, and a decrease in publications in PubMed's core clinical journal collection. Comparisons with New Zealand and the United Kingdom showed that Australia has had the greatest overall percentage increase in gross publication numbers and publications per capita. Our analyses confirm that increased HMR expenditure is associated with an increase in HMR publications in PubMed. Tracking HMR investment outcomes using this method could be useful for future policy and funding decisions at a federal and specific institution level. © 2015 Public Health Association of Australia.

  18. GOClonto: an ontological clustering approach for conceptualizing PubMed abstracts.

    Science.gov (United States)

    Zheng, Hai-Tao; Borchert, Charles; Kim, Hong-Gee

    2010-02-01

    Concurrent with progress in biomedical sciences, an overwhelming of textual knowledge is accumulating in the biomedical literature. PubMed is the most comprehensive database collecting and managing biomedical literature. To help researchers easily understand collections of PubMed abstracts, numerous clustering methods have been proposed to group similar abstracts based on their shared features. However, most of these methods do not explore the semantic relationships among groupings of documents, which could help better illuminate the groupings of PubMed abstracts. To address this issue, we proposed an ontological clustering method called GOClonto for conceptualizing PubMed abstracts. GOClonto uses latent semantic analysis (LSA) and gene ontology (GO) to identify key gene-related concepts and their relationships as well as allocate PubMed abstracts based on these key gene-related concepts. Based on two PubMed abstract collections, the experimental results show that GOClonto is able to identify key gene-related concepts and outperforms the STC (suffix tree clustering) algorithm, the Lingo algorithm, the Fuzzy Ants algorithm, and the clustering based TRS (tolerance rough set) algorithm. Moreover, the two ontologies generated by GOClonto show significant informative conceptual structures.

  19. Early Start Denver Model - intervention for de helt små børn med autisme

    DEFF Research Database (Denmark)

    Brynskov, Cecilia

    2015-01-01

    Early Start Denver Model (ESDM) er en autismespecifik interventionsmetode, som er udviklet til helt små børn med autisme (0-4 år). Metoden fokuserer på at styrke den tidlige kontakt og barnets motivation, og den arbejder målrettet med de socio-kommunikative forløbere for sprog og med den tidlige...

  20. Tæt på relationen

    DEFF Research Database (Denmark)

    Siersted, Mette

    1998-01-01

    sættes på begreb : teori og metode / Janne Hedegaard Hansen og Bent Madsen ; Velfærdsstaten i det moderne. Bent Madsen: Refleksion og fortolkning - i lyset af George Herbert Meads symbolske interaktionisme ; At beskrive praksis : fra empiri til praksisportræt. Med praksis som kilde til kundskab : otte...

  1. Research knowledge production and educational activity

    DEFF Research Database (Denmark)

    Chaiklin, Seth

    2013-01-01

    Den første del er en analytisk gennemgang om forhold i mellem pædagogisk forskning og pædagogisk praksis. Den anden del fremlægger en metodologisk perspektiv for hvordan man kan arbejde med at bruge forskning i forhold til praksis....

  2. Om performance og oplevelsesanalyse

    DEFF Research Database (Denmark)

    Nagbøl, Søren Peter; Flensborg, Ingelise

    2016-01-01

    , teori og praksis kan gennemføres i oplevelsesorienterede processer, hvor performance, sanselig praksis, transformeres til ting, sprog og billeder. Med afsæt i en konkret skulptur, Auguste Rodins (1840-1917) "Borgerne fra Calais", som er udstillet på Ny Carlsberg Glyptotek i København, giver vi eksempler...

  3. Kjemi 2

    DEFF Research Database (Denmark)

    Brandt, Harald; Hushovd, Odd T.

    Kemi 2 er et bogsystem til den gymnasiale kemiundervisning i Norge (VG3, studieforberedende) tilsvarende det danske kemi A-niveau i det almene gymnasium (stx). Lærebogen er et del af af et bogsystem med tilhørende netsted til elever og online-lærervejledning (lokus.no).......Kemi 2 er et bogsystem til den gymnasiale kemiundervisning i Norge (VG3, studieforberedende) tilsvarende det danske kemi A-niveau i det almene gymnasium (stx). Lærebogen er et del af af et bogsystem med tilhørende netsted til elever og online-lærervejledning (lokus.no)....

  4. Kjemi 1

    DEFF Research Database (Denmark)

    Brandt, Harald; Hushovd, Odd T.

    Kemi 1 er en lærebog til den gymnasiale kemiundervisning i Norge (VG2, studieforberedende) tilsvarende det danske kemi B-niveau i det almene gymnasium (stx). Lærebogen er et del af af et bogsystem med tilhørende netsted til elever og online-lærervejledning (lokus.no).......Kemi 1 er en lærebog til den gymnasiale kemiundervisning i Norge (VG2, studieforberedende) tilsvarende det danske kemi B-niveau i det almene gymnasium (stx). Lærebogen er et del af af et bogsystem med tilhørende netsted til elever og online-lærervejledning (lokus.no)....

  5. Best, Useful and Objective Precisions for Information Retrieval of Three Search Methods in PubMed and iPubMed

    Directory of Open Access Journals (Sweden)

    Somayyeh Nadi Ravandi

    2016-10-01

    Full Text Available MEDLINE is one of the valuable sources of medical information on the Internet. Among the different open access sites of MEDLINE, PubMed is the best-known site. In 2010, iPubMed was established with an interaction-fuzzy search method for MEDLINE access. In the present work, we aimed to compare the precision of the retrieved sources (Best, Useful and Objective precision in the PubMed and iPubMed using two search methods (simple and MeSH search in PubMed and interaction-fuzzy method in iPubmed. During our semi-empirical study period, we held training workshops for 61 students of higher education to teach them Simple Search, MeSH Search, and Fuzzy-Interaction Search methods. Then, the precision of 305 searches for each method prepared by the students was calculated on the basis of Best precision, Useful precision, and Objective precision formulas. Analyses were done in SPSS version 11.5 using the Friedman and Wilcoxon Test, and three precisions obtained with the three precision formulas were studied for the three search methods. The mean precision of the interaction-fuzzy Search method was higher than that of the simple search and MeSH search for all three types of precision, i.e., Best precision, Useful precision, and Objective precision, and the Simple search method was in the next rank, and their mean precisions were significantly different (P < 0.001. The precision of the interaction-fuzzy search method in iPubmed was investigated for the first time. Also for the first time, three types of precision were evaluated in PubMed and iPubmed. The results showed that the Interaction-Fuzzy search method is more precise than using the natural language search (simple search and MeSH search, and users of this method found papers that were more related to their queries; even though search in Pubmed is useful, it is important that users apply new search methods to obtain the best results.

  6. Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19.

    Science.gov (United States)

    Park, Min Ju; Shen, Hailian; Spaeth, Jason M; Tolvanen, Jaana H; Failor, Courtney; Knudtson, Jennifer F; McLaughlin, Jessica; Halder, Sunil K; Yang, Qiwei; Bulun, Serdar E; Al-Hendy, Ayman; Schenken, Robert S; Aaltonen, Lauri A; Boyer, Thomas G

    2018-03-30

    Somatic mutations in exon 2 of the RNA polymerase II transcriptional Mediator subunit MED12 occur at high frequency in uterine fibroids (UFs) and breast fibroepithelial tumors as well as recurrently, albeit less frequently, in malignant uterine leimyosarcomas, chronic lymphocytic leukemias, and colorectal cancers. Previously, we reported that UF-linked mutations in MED12 disrupt its ability to activate cyclin C (CycC)-dependent kinase 8 (CDK8) in Mediator, implicating impaired Mediator-associated CDK8 activity in the molecular pathogenesis of these clinically significant lesions. Notably, the CDK8 paralog CDK19 is also expressed in myometrium, and both CDK8 and CDK19 assemble into Mediator in a mutually exclusive manner, suggesting that CDK19 activity may also be germane to the pathogenesis of MED12 mutation-induced UFs. However, whether and how UF-linked mutations in MED12 affect CDK19 activation is unknown. Herein, we show that MED12 allosterically activates CDK19 and that UF-linked exon 2 mutations in MED12 disrupt its CDK19 stimulatory activity. Furthermore, we find that within the Mediator kinase module, MED13 directly binds to the MED12 C terminus, thereby suppressing an apparent UF mutation-induced conformational change in MED12 that otherwise disrupts its association with CycC-CDK8/19. Thus, in the presence of MED13, mutant MED12 can bind, but cannot activate, CycC-CDK8/19. These findings indicate that MED12 binding is necessary but not sufficient for CycC-CDK8/19 activation and reveal an additional step in the MED12-dependent activation process, one critically dependent on MED12 residues altered by UF-linked exon 2 mutations. These findings confirm that UF-linked mutations in MED12 disrupt composite Mediator-associated kinase activity and identify CDK8/19 as prospective therapeutic targets in UFs. © 2018 Park et al.

  7. Papillae formation on trichome cell walls requires the function of the mediator complex subunit Med25.

    Science.gov (United States)

    Fornero, Christy; Suo, Bangxia; Zahde, Mais; Juveland, Katelyn; Kirik, Viktor

    2017-11-01

    Glassy Hair 1 (GLH1) gene that promotes papillae formation on trichome cell walls was identified as a subunit of the transcriptional mediator complex MED25. The MED25 gene is shown to be expressed in trichomes. The expression of the trichome development marker genes GLABRA2 (GL2) and Ethylene Receptor2 (ETR2) is not affected in the glh1 mutant. Presented data suggest that Arabidopsis MED25 mediator component is likely involved in the transcription of genes promoting papillae deposition in trichomes. The plant cell wall plays an important role in communication, defense, organization and support. The importance of each of these functions varies by cell type. Specialized cells, such as Arabidopsis trichomes, exhibit distinct cell wall characteristics including papillae. To better understand the molecular processes important for papillae deposition on the cell wall surface, we identified the GLASSY HAIR 1 (GLH1) gene, which is necessary for papillae formation. We found that a splice-site mutation in the component of the transcriptional mediator complex MED25 gene is responsible for the near papillae-less phenotype of the glh1 mutant. The MED25 gene is expressed in trichomes. Reporters for trichome developmental marker genes GLABRA2 (GL2) and Ethylene Receptor2 (ETR2) were not affected in the glh1 mutant. Collectively, the presented results show that MED25 is necessary for papillae formation on the cell wall surface of leaf trichomes and suggest that the Arabidopsis MED25 mediator component is likely involved in the transcription of a subset of genes that promote papillae deposition in trichomes.

  8. Improving accuracy for identifying related PubMed queries by an integrated approach.

    Science.gov (United States)

    Lu, Zhiyong; Wilbur, W John

    2009-10-01

    PubMed is the most widely used tool for searching biomedical literature online. As with many other online search tools, a user often types a series of multiple related queries before retrieving satisfactory results to fulfill a single information need. Meanwhile, it is also a common phenomenon to see a user type queries on unrelated topics in a single session. In order to study PubMed users' search strategies, it is necessary to be able to automatically separate unrelated queries and group together related queries. Here, we report a novel approach combining both lexical and contextual analyses for segmenting PubMed query sessions and identifying related queries and compare its performance with the previous approach based solely on concept mapping. We experimented with our integrated approach on sample data consisting of 1539 pairs of consecutive user queries in 351 user sessions. The prediction results of 1396 pairs agreed with the gold-standard annotations, achieving an overall accuracy of 90.7%. This demonstrates that our approach is significantly better than the previously published method. By applying this approach to a one day query log of PubMed, we found that a significant proportion of information needs involved more than one PubMed query, and that most of the consecutive queries for the same information need are lexically related. Finally, the proposed PubMed distance is shown to be an accurate and meaningful measure for determining the contextual similarity between biological terms. The integrated approach can play a critical role in handling real-world PubMed query log data as is demonstrated in our experiments.

  9. Den fuldt åbne MOOC med afsæt i aktuelle deltagere

    DEFF Research Database (Denmark)

    Hansbøl, Mikala; Erkmann, Malene; Munksgaard, Marianne Eilsø

    2015-01-01

    I dette afsnit præsenterer vi nogle af erfaringerne fra arbejdet med fire versioner af Videnskabsteori MOOC’en. Erfaringerne tager afsæt i vores kvalitative undersøgelser af deltagerperspektiver (UCSJ undervisere og MOOC deltagere) på MOOC-understøttet undervisning i, og læring af, anvendt...... videnskabsteori. MOOC litteraturen havde indtil 2013 primært beskæftiget sig med universitetsuddannelse, og der var stort set ikke skrevet noget om MOOCs i en dansk sammenhæng. Kjærgaard et al. (2013) leverede et første dansk bidrag, der kobler MOOCs med professionshøjskolerne i Danmark. Arbejdet med...... Videnskabsteori MOOC’en har især taget afsæt i en interesse i at forstå samspillet mellem deltagerforudsætninger, interesser og behov, og læringsmulighederne med MOOC’en. På den baggrund udpeger vi nogle væsentlige designelementer, der kan medtænkes i fremtidige udviklinger af tilsvarende fuldt åbne MOOCs...

  10. MED, COMP, multilayered and NEIN: an overview of multiple epiphyseal dysplasia

    Energy Technology Data Exchange (ETDEWEB)

    Lachman, Ralph S. [International Skeletal Dysplasia Registry, UCLA School of Medicine, Radiological Services, Department of Pediatrics, Los Angeles, CA (United States); International Skeletal Dysplasia Registry, Los Angeles, CA (United States); Krakow, Deborah; Cohn, Daniel H.; Rimoin, David L. [International Skeletal Dysplasia Registry, UCLA School of Medicine, Radiological Services, Department of Pediatrics, Los Angeles, CA (United States)

    2005-02-01

    This overview covers the group of disorders that presents radiographically as multiple epiphyseal dysplasia (MED). The disorders include ''classic MED'' (Ribbing and Fairbank types): MED that is caused by mutations in the cartilage oligomeric matrix protein (COMP), type IX collagen, and matrilin 3 genes (MATN3); and MED with multilayered patella, brachydactyly, and clubbed feet resultant from mutations in gene defect diastrophic dysplasia (DTDST). The recently identified gene/molecular abnormalities in these disorders have made more exact identification possible in many cases, although clinical testing is not always available. However, there are specific radiographic findings that allow the accurate diagnosis to be made, thus potentially guiding which molecular defect(s) should be investigated. The modes of inheritance of these distinct MED conditions are not identical. When a specific diagnosis is made, proper genetic counseling as well as prognostication, management issues and complications can be delineated to the patient and family. This review will include the mechanics of diagnostic and molecular triage for these disorders. (orig.)

  11. A New Method for Weak Fault Feature Extraction Based on Improved MED

    Directory of Open Access Journals (Sweden)

    Junlin Li

    2018-01-01

    Full Text Available Because of the characteristics of weak signal and strong noise, the low-speed vibration signal fault feature extraction has been a hot spot and difficult problem in the field of equipment fault diagnosis. Moreover, the traditional minimum entropy deconvolution (MED method has been proved to be used to detect such fault signals. The MED uses objective function method to design the filter coefficient, and the appropriate threshold value should be set in the calculation process to achieve the optimal iteration effect. It should be pointed out that the improper setting of the threshold will cause the target function to be recalculated, and the resulting error will eventually affect the distortion of the target function in the background of strong noise. This paper presents an improved MED based method of fault feature extraction from rolling bearing vibration signals that originate in high noise environments. The method uses the shuffled frog leaping algorithm (SFLA, finds the set of optimal filter coefficients, and eventually avoids the artificial error influence of selecting threshold parameter. Therefore, the fault bearing under the two rotating speeds of 60 rpm and 70 rpm is selected for verification with typical low-speed fault bearing as the research object; the results show that SFLA-MED extracts more obvious bearings and has a higher signal-to-noise ratio than the prior MED method.

  12. National trivselsdag med fokus på bevægelse

    DEFF Research Database (Denmark)

    Holt, Anne-Didde

    2016-01-01

    breaks”, skriver tre elever. Trivselsdagen gav ligeledes anledning til at dele de gode erfaringer, der indtil nu er udsprunget af ’Trivsel og Bevægelse i Skolen’ - P1 Morgen, P4 Fyn og TV-avisen bragte historier fra dagen på Glamsbjergskolen i Assens, mens P4 Midt og Vest besøgte Haldgård Skole i...... til at fordybe sig i, videreudvikle og vise omverdenen, hvordan der arbejdes med at fremme trivsel gennem bevægelse. Eleverne arbejdede bl.a. med at udvikle og afprøve brain breaks, som er små pauser med bevægelsesaktiviteter, der lægges ind i løbet af den stillesiddende undervisning. Formålet var...... for dem. ”Vi synes brain breaks er vigtige fordi med brain breaks får vi meget mere energi og fordi at man får et bedre forhold til sine klassekammerater, som man måske ikke snakker med så tit. Man kan holde til mere og det er vigtigt at få en pause til at tænke så derfor vil vi gerne have flere brain...

  13. Forsøg med 4 centralt belastede betonelementer samt 4 tilhørende betoncylindre

    DEFF Research Database (Denmark)

    Ellegaard, Peter; Hansen, Lars Pilegaard

    Nærværende rapport indeholder beskrivelser og resultater for en række forsøg udført i Laboratoriet for Bærende Konstruktioner, Aalborg Universitet. Prøvelegemerne, som er nærmere beskrevet i kapitel 1, består af 4 betonelementer med en længde på 2600 mm og et tværsnitsareal på 400x120 mm. Element......Nærværende rapport indeholder beskrivelser og resultater for en række forsøg udført i Laboratoriet for Bærende Konstruktioner, Aalborg Universitet. Prøvelegemerne, som er nærmere beskrevet i kapitel 1, består af 4 betonelementer med en længde på 2600 mm og et tværsnitsareal på 400x120 mm....... Elementerne er belastet centralt med tryk, og de er forsynet med transportarmering. Til bestemmelse af betonens brudstyrke og arbejdskurve op til 75% af brudstyrken er der udført forsøg på 4betoncylindre med diameter 100 mm og højde 200 mm. Elementerne og cylinderne er fremstillet af Fårup Betonindustri A...

  14. Observing floods from space: Experience gained from COSMO-SkyMed observations

    Science.gov (United States)

    Pierdicca, N.; Pulvirenti, L.; Chini, M.; Guerriero, L.; Candela, L.

    2013-03-01

    The COSMO-SkyMed mission offers a unique opportunity to obtain all weather radar images characterized by short revisit time, thus being useful for flood evolution mapping. The COSMO-SkyMed system has been activated several times in the last few years in occasion of flood events all over the world in order to provide very high resolution X-band SAR images useful for flood detection purposes. This paper discusses the major outcomes of the experience gained, within the framework of the OPERA Pilot Project funded by the Italian Space Agency, from using COSMO-SkyMed data for the purpose of near real time generation of flood maps. A review of the mechanisms which determine the imprints of the inundation on the radar images and of the fundamental simulation tools able to predict these imprints and help image interpretation is provided. The approach developed to process the data and to generate the flood maps is also summarized. Then, the paper illustrates the experience gained with COSMO-SkyMed by describing and discussing a number of significant examples. These examples demonstrate the potential of the COSMO-SkyMed system and the suitability of the approach developed for generating the final products, but they also highlight some critical aspects that require further investigations to improve the reliability of the flood maps.

  15. Graduating med-peds residents' interest in part-time employment.

    Science.gov (United States)

    Fix, Amy L; Kaelber, David C; Melgar, Thomas A; Chamberlain, John; Cull, William; Robbins, Brett W

    2011-01-01

    As part-time work is becoming more popular among the primary care specialties, we examined the demographic descriptors of med-peds residents seeking and finding part-time employment upon completion of residency training. As part of the 2006 annual American Academy of Pediatrics (AAP) Graduating Med-Peds Residents Survey, we surveyed the graduating residents of all med-peds programs about their interest in and plans for part-time employment. A total of 199 (60%) of the residents responded. Of the resident respondents applying for nonfellowship jobs, 19% sought part-time positions and 10% actually accepted a part-time position. Female residents were significantly more likely than male residents to apply for part-time jobs (26% vs. 7%, P = .034). Sixty percent of female residents immediately seeking work and 58% of those going on to fellowship reported an interest in arranging a part-time or reduced-hours position at some point in the next 5 years. Part-time employment among med-peds residents applying for nonfellowship positions after graduation is similar to the current incidence of part-time employment in other fields of primary care. A much higher percentage of med-peds residents are interested in arranging part-time work within 5 years after graduation. This strong interest in part-time work has many implications for the primary care workforce. Copyright © 2011 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

  16. Clinical safety of magnetic resonance imaging in patients with implanted SynchroMed EL infusion pumps

    International Nuclear Information System (INIS)

    Diehn, Felix E.; Wood, Christopher P.; Watson, Robert E.; Hunt, Christopher H.; Mauck, William D.; Burke, Michelle M.

    2011-01-01

    Patients with implanted SynchroMed spinal infusion pumps (Medtronic, Inc., Minneapolis, MN) routinely undergo magnetic resonance imaging at our institution. In August 2008, Medtronic issued an urgent medical device correction report regarding several pumps. Because of the rare potential ''for a delay in the return of proper drug infusion'' and ''for a delay in the logging of motor stall events,'' ''a patient's pump must be interrogated after MRI exposure in order to confirm proper pump functionality.'' This is particularly important in patients receiving intrathecal baclofen, for whom a delay in return of proper pump infusion could lead to life-threatening baclofen withdrawal syndrome. The objective of this report is to present our experience and protocol of performing magnetic resonance imaging in patients with implanted SynchroMed EL pumps. We retrospectively reviewed records of 86 patients with implanted SynchroMed EL spinal infusion pumps who underwent 112 examinations on 1.5-T magnetic resonance imaging scanners from September 1, 1998 to July 7, 2004. No SynchroMed EL pumps were damaged by magnetic resonance imaging, and the programmable settings remained unchanged in all patients. Our data suggest that SynchroMed EL pump malfunction is indeed rare after routine clinical 1.5-T magnetic resonance imaging examinations. However, based on the Medtronic correction report, we perform pump interrogation before and after imaging. (orig.)

  17. ProMED-mail: 22 years of digital surveillance of emerging infectious diseases.

    Science.gov (United States)

    Carrion, Malwina; Madoff, Lawrence C

    2017-05-01

    ProMED-mail (ProMED) was launched in 1994 as an email service to identify unusual health events related to emerging and re-emerging infectious diseases and toxins affecting humans, animals and plants. It is used daily by public health leaders, government officials at all levels, physicians, veterinarians and other healthcare workers, researchers, private companies, journalists and the general public. Reports are produced and commentary provided by a global team of subject matter experts in a variety of fields including virology, parasitology, epidemiology, entomology, veterinary and plant disease specialists. ProMED operates 24 hours a day, 7 days a week and has over 83 000 subscribers, representing every country in the world. Additionally, ProMED disseminates information via its website and through social media channels such as Twitter and Facebook as well as through RSS feeds. Over the last 22 years, it has been the first to report on numerous major and minor disease outbreaks including SARS, MERS, Ebola and the early spread of Zika. ProMED is transparent, apolitical, open to all and free of charge, making it an important and longstanding contributor to global health surveillance. © The Author 2017. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  18. Mediator MED23 Links Pigmentation and DNA Repair through the Transcription Factor MITF.

    Science.gov (United States)

    Xia, Min; Chen, Kun; Yao, Xiao; Xu, Yichi; Yao, Jiaying; Yan, Jun; Shao, Zhen; Wang, Gang

    2017-08-22

    DNA repair is related to many physiological and pathological processes, including pigmentation. Little is known about the role of the transcriptional cofactor Mediator complex in DNA repair and pigmentation. Here, we demonstrate that Mediator MED23 plays an important role in coupling UV-induced DNA repair to pigmentation. The loss of Med23 specifically impairs the pigmentation process in melanocyte-lineage cells and in zebrafish. Med23 deficiency leads to enhanced nucleotide excision repair (NER) and less DNA damage following UV radiation because of the enhanced expression and recruitment of NER factors to chromatin for genomic stability. Integrative analyses of melanoma cells reveal that MED23 controls the expression of a melanocyte master regulator, Mitf, by modulating its distal enhancer activity, leading to opposing effects on pigmentation and DNA repair. Collectively, the Mediator MED23/MITF axis connects DNA repair to pigmentation, thus providing molecular insights into the DNA damage response and skin-related diseases. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

  19. PubMed Phrases, an open set of coherent phrases for searching biomedical literature

    Science.gov (United States)

    Kim, Sun; Yeganova, Lana; Comeau, Donald C.; Wilbur, W. John; Lu, Zhiyong

    2018-01-01

    In biomedicine, key concepts are often expressed by multiple words (e.g., ‘zinc finger protein’). Previous work has shown treating a sequence of words as a meaningful unit, where applicable, is not only important for human understanding but also beneficial for automatic information seeking. Here we present a collection of PubMed® Phrases that are beneficial for information retrieval and human comprehension. We define these phrases as coherent chunks that are logically connected. To collect the phrase set, we apply the hypergeometric test to detect segments of consecutive terms that are likely to appear together in PubMed. These text segments are then filtered using the BM25 ranking function to ensure that they are beneficial from an information retrieval perspective. Thus, we obtain a set of 705,915 PubMed Phrases. We evaluate the quality of the set by investigating PubMed user click data and manually annotating a sample of 500 randomly selected noun phrases. We also analyze and discuss the usage of these PubMed Phrases in literature search. PMID:29893755

  20. MET network in PubMed: a text-mined network visualization and curation system.

    Science.gov (United States)

    Dai, Hong-Jie; Su, Chu-Hsien; Lai, Po-Ting; Huang, Ming-Siang; Jonnagaddala, Jitendra; Rose Jue, Toni; Rao, Shruti; Chou, Hui-Jou; Milacic, Marija; Singh, Onkar; Syed-Abdul, Shabbir; Hsu, Wen-Lian

    2016-01-01

    Metastasis is the dissemination of a cancer/tumor from one organ to another, and it is the most dangerous stage during cancer progression, causing more than 90% of cancer deaths. Improving the understanding of the complicated cellular mechanisms underlying metastasis requires investigations of the signaling pathways. To this end, we developed a METastasis (MET) network visualization and curation tool to assist metastasis researchers retrieve network information of interest while browsing through the large volume of studies in PubMed. MET can recognize relations among genes, cancers, tissues and organs of metastasis mentioned in the literature through text-mining techniques, and then produce a visualization of all mined relations in a metastasis network. To facilitate the curation process, MET is developed as a browser extension that allows curators to review and edit concepts and relations related to metastasis directly in PubMed. PubMed users can also view the metastatic networks integrated from the large collection of research papers directly through MET. For the BioCreative 2015 interactive track (IAT), a curation task was proposed to curate metastatic networks among PubMed abstracts. Six curators participated in the proposed task and a post-IAT task, curating 963 unique metastatic relations from 174 PubMed abstracts using MET.Database URL: http://btm.tmu.edu.tw/metastasisway. © The Author(s) 2016. Published by Oxford University Press.

  1. Software-Enabled Distributed Network Governance: The PopMedNet Experience.

    Science.gov (United States)

    Davies, Melanie; Erickson, Kyle; Wyner, Zachary; Malenfant, Jessica; Rosen, Rob; Brown, Jeffrey

    2016-01-01

    The expanded availability of electronic health information has led to increased interest in distributed health data research networks. The distributed research network model leaves data with and under the control of the data holder. Data holders, network coordinating centers, and researchers have distinct needs and challenges within this model. The concerns of network stakeholders are addressed in the design and governance models of the PopMedNet software platform. PopMedNet features include distributed querying, customizable workflows, and auditing and search capabilities. Its flexible role-based access control system enables the enforcement of varying governance policies. Four case studies describe how PopMedNet is used to enforce network governance models. Trust is an essential component of a distributed research network and must be built before data partners may be willing to participate further. The complexity of the PopMedNet system must be managed as networks grow and new data, analytic methods, and querying approaches are developed. The PopMedNet software platform supports a variety of network structures, governance models, and research activities through customizable features designed to meet the needs of network stakeholders.

  2. Clinical safety of magnetic resonance imaging in patients with implanted SynchroMed EL infusion pumps

    Energy Technology Data Exchange (ETDEWEB)

    Diehn, Felix E.; Wood, Christopher P.; Watson, Robert E.; Hunt, Christopher H. [Mayo Clinic, Department of Radiology, Rochester, MN (United States); Mauck, William D. [Mayo Clinic, Department of Anesthesiology, Rochester, MN (United States); Burke, Michelle M. [Mayo Clinic, Department of Psychiatry and Psychology, Rochester, MN (United States)

    2011-02-15

    Patients with implanted SynchroMed spinal infusion pumps (Medtronic, Inc., Minneapolis, MN) routinely undergo magnetic resonance imaging at our institution. In August 2008, Medtronic issued an urgent medical device correction report regarding several pumps. Because of the rare potential ''for a delay in the return of proper drug infusion'' and ''for a delay in the logging of motor stall events,'' ''a patient's pump must be interrogated after MRI exposure in order to confirm proper pump functionality.'' This is particularly important in patients receiving intrathecal baclofen, for whom a delay in return of proper pump infusion could lead to life-threatening baclofen withdrawal syndrome. The objective of this report is to present our experience and protocol of performing magnetic resonance imaging in patients with implanted SynchroMed EL pumps. We retrospectively reviewed records of 86 patients with implanted SynchroMed EL spinal infusion pumps who underwent 112 examinations on 1.5-T magnetic resonance imaging scanners from September 1, 1998 to July 7, 2004. No SynchroMed EL pumps were damaged by magnetic resonance imaging, and the programmable settings remained unchanged in all patients. Our data suggest that SynchroMed EL pump malfunction is indeed rare after routine clinical 1.5-T magnetic resonance imaging examinations. However, based on the Medtronic correction report, we perform pump interrogation before and after imaging. (orig.)

  3. Solar-assisted MED treatment of Eskom power station waste water

    Science.gov (United States)

    Roos, Thomas H.; Rogers, David E. C.; Gericke, Gerhard

    2017-06-01

    The comparative benefits of multi-effect distillation (MED) used in conjunction with Nano Filtration (NF), Reverse Osmosis (RO) and Eutectic Freeze Crystallization (EFC) are determined for waste water minimization for inland coal fired power stations for Zero Liquid Effluent Discharge (ZLED). A sequence of technologies is proposed to achieve maximal water recovery and brine concentration: NF - physico-chemical treatment - MED - EFC. The possibility of extending the concentration of RO reject arising from minewater treatment at the Lethabo power station with MED alone is evaluated with mineral formation modelling using the thermochemical modelling software Phreeq-C. It is shown that pretreatment is essential to extend the amount of water that can be recovered, and this can be beneficially supported by NF.

  4. På kant med naturen - om byøkologien og det åbne land

    DEFF Research Database (Denmark)

    Schjerup Hansen, J.(red.); Hjortholt Madsen, S.(red.)

    Den erkendelse, at vores produktionsmåde og levevis i høj grad har bragt os på kant med naturen og på lidt længere sigt på kant med vort eget eksistensgrundlag, breder sig. En samfundsmæssig selvreflektion har allerede udmøntet sig i begreber som renere teknologi, byøkologi og bæredygtig adfærd. I...... tidens selvreflektion ligger, at vort forhold til naturen i høj grad er et "indre anliggende": Vi er selv natur, og det er vores egen måde at tænke og handle på i forhold til naturen, der har bragt os på kant med naturen - og os selv....

  5. Indsats for forældre til børn med ADHD

    DEFF Research Database (Denmark)

    Neubert, Katja

    2012-01-01

    Et nyt review, udarbejdet af forskergruppen omkring Morris Zwi, undersøger om interventionsprogrammer til forældre til børn med ADHD er effektive, når det gælder reducering af børnenes ADHD-relaterede adfærd og associerede problemer som eksempelvis indlæringsproblemer. Reviewet peger på, at en...... indsats til forældre til børn med ADHD kan have en gavnlig effekt på børnenes adfærd. Interventionen kan også være med til at sænke stressniveauet hos forældre til disse børn, og forbedre forældrenes selvtillid....

  6. Tidlige brukere av alkohol – hvem er de? Kjennetegn ved ungdom som starter tidlig med alkohol

    Directory of Open Access Journals (Sweden)

    Anders Grimsmo

    2009-10-01

    Full Text Available  SAMMENDRAGDebutalder med alkoholrus er en sterk prediktor for senere alkoholbruk. I denne undersøkelsen har visammenliknet de som starter med alkohol tidlig og før det er kulturelt akseptert, med ungdommenesom begynner i konfirmasjonsalder og de som utsetter alkoholdebuten. Vi finner at gruppen sombegynner tidlig ikke bare bryter de lokale tradisjonene for alkoholkonsum, men er i opposisjon tilnormer og autoriteter generelt. Alkohol er et positivt symbol for gruppen og det å ruse seg et ritualesom gir mening i deres miljø. Hjemmet står i den sterkeste posisjonen til å kunne utsette ungdommensalkoholdebut. Vi skisserer hvilke implikasjoner dette bør ha for strategien i det forebyggende arbeidet.

  7. Med politiet i ’virkeligheden’: Reality-tv og kriminalitet

    Directory of Open Access Journals (Sweden)

    Ib Bondebjerg

    2002-09-01

    Full Text Available Kriminalstoffet på tv bliver ofte anklaget for at spekulere i vore lavere instinkter, og med reality kommer vi tættere end nogensinde på sam- fundets bund og det utrættelige politi, som har til opgave at opretholde lov og orden. Artiklen gennemgår en lang række af de senere års kri- minalprogrammer og diskuterer dokumentarismens former med en særlig belysning af æstetik, retorik og synsvinkel i undergenrerne »reality magasin« og »reality soap«. Lars Engels’ serie »Historier fra en politistation« tages op til særlig debat, fordi Engels – vanen tro – arbejder med en mindre iscenesættelse og ukommenteret virkelig- hedsgengivelse, end vi finder det i andre »reality soaps«.

  8. LIVIVO: Neue Herausforderungen an das ZB MED-Suchportal für Lebenswissenschaften

    Directory of Open Access Journals (Sweden)

    Poley, Christoph

    2016-12-01

    Full Text Available The German National Library of Medicine (ZB MED has a long track record providing search portals for life sciences. In 2015 LIVIVO was introduced as a new product, which database covers ZB MED’s entire range of subjects: medicine, health, nutrition, environment and agriculture.Initially LIVIVO’s development aimed at realizing a modern search engine combining the functionalities of the predecessor portals. An entirely new web interface was developed, driven by a highly improved usability and a responsive web design. LIVIVO has a great potential in providing search services based on more than 55 million metadata records. Current work of ZB MED focuses on automatic interfaces. Concurrently setting up ZB MED Knowledge Environment creates an indispensable data base for research work at .This article will address the current challenges of a scientific portal using the example of LIVIVO. It will outline the approaches to solutions and development lines.

  9. Projekt Frit Sind hjælper mennesker med social angst

    DEFF Research Database (Denmark)

    Moutamid, Mina El

    2017-01-01

    Social angst er en almindelig, men overset lidelse, som ofte er forbundet med isolation. Mange fortæller ikke om den angst, de oplever, til andre og kommer til at leve et liv med begrænsninger, som de kunne være foruden, hvis de fik hjælp. Angsten betyder også, at det kan være svært at komme...... hjemmefra og opsøge hjælp hos SIND eller andre rådgivninger. Frit Sind er et nyt tilbud i København til disse mennesker og har fokus på de specifikke behov, mennesker med social angst har....

  10. Enriching PubMed Related Article Search with Sentence Level Co-citations

    Science.gov (United States)

    Tran, Nam; Alves, Pedro; Ma, Shuangge

    2009-01-01

    PubMed related article links identify closely related articles and enhance our ability to navigate the biomedical literature. They are derived by calculating the word similarity between two articles, relating articles with overlapping word content. In this paper, we propose to enrich PubMed with a new type of related article link based on citations within a single sentence (i.e. sentence level co-citations or SLCs). Using different similarity metrics, we demonstrated that articles linked by SLCs are highly related. We also showed that only half of SLCs are found among PubMed related article links. Additionally, we discuss how the citing sentence of an SLC explains the connection between two articles. PMID:20351935

  11. Management of data from clinical trials using the ArchiMed system.

    Science.gov (United States)

    Duftschmid, Georg; Gall, Walter; Eigenbauer, Ernst; Dorda, Wolfgang

    2002-06-01

    Clinical trials constitute a key source of medical research and are therefore conducted on a regular basis at university hospitals. The professional execution of trials requires, among other things, a repertoire of tools that support efficient data management. Tasks that are essential for efficient data management in clinical trials include the following: the design of the trial database, the design of electronic case report forms, recruiting patients, collection of data, and statistical analysis. The present article reports the manner in which these tasks are supported by the ArchiMed system at the University of Vienna and Graz Medical Schools. ArchiMed is customized for clinical end users, allowing them to autonomously manage their clinical trials without having to consult computer experts. An evaluation of the ArchiMed system in 12 trials recently conducted at the University of Vienna Medical School shows that the individual system functions can be usefully applied for data management in clinical trials.

  12. Kommunikation ved brug af mobile enheder med digital video i idræt

    DEFF Research Database (Denmark)

    Langagergaard Rødbro, Lise; Elbæk, Lars

    2012-01-01

    I artiklen redegøres kort for et projekt, som førte frem til en videoplatform, der er et bud på et ’lukket YouTube’, hvor video filmet med smartphone direkte kan uploades til, og med funktioner specifikt udviklet til skolens idrætsundervisning. Med afsæt i systemisk kommunikationsteori analyseres...... observations- og interviewda-ta for at belyse den kommunikation, der foregår ved brug af platformen. Senere diskuteres resultaterne ud fra kommunikationstrekanten, og der skitseres en model for videostøttet undervisning i idræt ud fra Batesons kommunikations- og læringsniveauer. Gennem analyser af platformens...

  13. Musik og billeddannelse (GIM med PTSD-ramte flygtninge: Introduktion til tre single case-studier

    Directory of Open Access Journals (Sweden)

    Bolette Daniels Beck

    2016-12-01

    Full Text Available Mange flygtninge kommer fra kulturer med helt andre forestillinger og begreber om årsager til og forventninger om behandling af psykisk lidelse end man almindeligvis anvender i psykiatrien. F.eks. er psykisk lidelse i mange mellemøstlige kulturer forbundet med skam, og udtrykkes måske derfor snarere i form af fysisk smerte. For at et behandlingsforløb skal lykkes, er der behov for kulturel sensitivitet hos behandleren, når der skal samarbejdes med tolken, skabes et møde på tværs af kulturer samt etableres en fælles forståelse af behandlingens formål og proces.

  14. TeleMed: Wide-area, secure, collaborative object computing with Java and CORBA for healthcare

    Energy Technology Data Exchange (ETDEWEB)

    Forslund, D.W.; George, J.E.; Gavrilov, E.M.

    1998-12-31

    Distributed computing is becoming commonplace in a variety of industries with healthcare being a particularly important one for society. The authors describe the development and deployment of TeleMed in a few healthcare domains. TeleMed is a 100% Java distributed application build on CORBA and OMG standards enabling the collaboration on the treatment of chronically ill patients in a secure manner over the Internet. These standards enable other systems to work interoperably with TeleMed and provide transparent access to high performance distributed computing to the healthcare domain. The goal of wide scale integration of electronic medical records is a grand-challenge scale problem of global proportions with far-reaching social benefits.

  15. #GeriMedJC: The Twitter Complement to the Traditional-Format Geriatric Medicine Journal Club.

    Science.gov (United States)

    Gardhouse, Amanda I; Budd, Laura; Yang, Seu Y C; Wong, Camilla L

    2017-06-01

    Twitter is a public microblogging platform that overcomes physical limitations and allows unrestricted participation beyond academic silos, enabling interactive discussions. Twitter-based journal clubs have demonstrated growth, sustainability, and worldwide communication, using a hashtag (#) to follow participation. This article describes the first year of #GeriMedJC, a monthly 1-hour live, 23-hour asynchronous Twitter-based complement to the traditional-format geriatric medicine journal club. The Twitter moderator tweets from the handle @GeriMedJC; encourages use of #GeriMedJC; and invites content experts, study authors, and followers to participate in critical appraisal of medical literature. Using the hashtag #GeriMedJC, tweets were categorized according to thematic content, relevance to the journal club, and authorship. Third-party analytical tools Symplur and Twitter Analytics were used for growth and effect metrics (number of followers, participants, tweets, retweets, replies, impressions). Qualitative analysis of follower and participant profiles was used to establish country of origin and occupation. A semistructured interview of postgraduate trainees was conducted to ascertain qualitative aspects of the experience. In the first year, @GeriMedJC has grown to 541 followers on six continents. Most followers were physicians (43%), two-thirds of which were geriatricians. Growth metrics increased over 12 months, with a mean of 121 tweets, 25 participants, and 105,831 impressions per journal club. Tweets were most often related to the article being appraised (87.5%) and ranged in thematic content from clinical practice (29%) to critical appraisal (24%) to medical education (20%). #GeriMedJC is a feasible example of using social media platforms such as Twitter to encourage international and interprofessional appraisal of medical literature. © 2017, Copyright the Authors Journal compilation © 2017, The American Geriatrics Society.

  16. MED: a new non-supervised gene prediction algorithm for bacterial and archaeal genomes

    Directory of Open Access Journals (Sweden)

    Yang Yi-Fan

    2007-03-01

    Full Text Available Abstract Background Despite a remarkable success in the computational prediction of genes in Bacteria and Archaea, a lack of comprehensive understanding of prokaryotic gene structures prevents from further elucidation of differences among genomes. It continues to be interesting to develop new ab initio algorithms which not only accurately predict genes, but also facilitate comparative studies of prokaryotic genomes. Results This paper describes a new prokaryotic genefinding algorithm based on a comprehensive statistical model of protein coding Open Reading Frames (ORFs and Translation Initiation Sites (TISs. The former is based on a linguistic "Entropy Density Profile" (EDP model of coding DNA sequence and the latter comprises several relevant features related to the translation initiation. They are combined to form a so-called Multivariate Entropy Distance (MED algorithm, MED 2.0, that incorporates several strategies in the iterative program. The iterations enable us to develop a non-supervised learning process and to obtain a set of genome-specific parameters for the gene structure, before making the prediction of genes. Conclusion Results of extensive tests show that MED 2.0 achieves a competitive high performance in the gene prediction for both 5' and 3' end matches, compared to the current best prokaryotic gene finders. The advantage of the MED 2.0 is particularly evident for GC-rich genomes and archaeal genomes. Furthermore, the genome-specific parameters given by MED 2.0 match with the current understanding of prokaryotic genomes and may serve as tools for comparative genomic studies. In particular, MED 2.0 is shown to reveal divergent translation initiation mechanisms in archaeal genomes while making a more accurate prediction of TISs compared to the existing gene finders and the current GenBank annotation.

  17. The Tlo Proteins Are Stoichiometric Components of Candida albicans Mediator Anchored via the Med3 Subunit

    Science.gov (United States)

    Zhang, Anda; Petrov, Kostadin O.; Hyun, Emily R.; Liu, Zhongle; Gerber, Scott A.

    2012-01-01

    The amplification of the TLO (for telomere-associated) genes in Candida albicans, compared to its less pathogenic, close relative Candida dubliniensis, suggests a role in virulence. Little, however, is known about the function of the Tlo proteins. We have purified the Mediator coactivator complex from C. albicans (caMediator) and found that Tlo proteins are a stoichiometric component of caMediator. Many members of the Tlo family are expressed, and each is a unique member of caMediator. Protein expression analysis of individual Tlo proteins, as well as the purification of tagged Tlo proteins, demonstrate that there is a large free population of Tlo proteins in addition to the Mediator-associated population. Coexpression and copurification of Tloα12 and caMed3 in Escherichia coli established a direct physical interaction between the two proteins. We have also made a C. albicans med3Δ/Δ strain and purified an intact Mediator from this strain. The analysis of the composition of the med3Δ Mediator shows that it lacks a Tlo subunit. Regarding Mediator function, the med3Δ/Δ strain serves as a substitute for the difficult-to-make tloΔ/Δ C. albicans strain. A potential role of the TLO and MED3 genes in virulence is supported by the inability of the med3Δ/Δ strain to form normal germ tubes. This study of caMediator structure provides initial clues to the mechanism of action of the Tlo genes and a platform for further mechanistic studies of caMediator's involvement in gene regulatory patterns that underlie pathogenesis. PMID:22562472

  18. Hovedpointer fra telefon survey med D&I kandidater og aftagere

    DEFF Research Database (Denmark)

    Brodersen, Søsser; Lindegaard, Hanne

    2010-01-01

    Som en anden fase i D&I evalueringen gennemførtes en telefon survey med alle færdige D&I kandidater (i perioden september til november 2009). Formålet med denne telefon survey var at kortlægge kandidaternes karriereforløb: mønstrer, entre på arbejdsmarkedet og hvor søger de job, beskæftigelsesmøn......Som en anden fase i D&I evalueringen gennemførtes en telefon survey med alle færdige D&I kandidater (i perioden september til november 2009). Formålet med denne telefon survey var at kortlægge kandidaternes karriereforløb: mønstrer, entre på arbejdsmarkedet og hvor søger de job......, beskæftigelsesmønstrer samt hvilke kompetencer de mener at have anvendt og ikke anvendt fra studiet i deres job. Telefon survey formen blev valgt for dermed at få muligheden for at få nogle kvantitative informationer frem. I alt blev 72 D&I kandidater interviewet ud af 78 mulige, dvs. vi opnåede en svarprocent på 92......,3 % . Spørgsmålene var forberedt på forhånd således at kandidaterne blev stillet de samme spørgsmål. Derudover gennemførtes en telefon survey med 14 aftagere af D&I kandidater (identificeret gennem telefon surveyen med kandidaterne, således at de repræsenterede store virksomheder, mindre virksomheder...

  19. Hvem er mest fornøyd med samlivet? : samlivskvalitet blant samboere og gifte

    OpenAIRE

    Wiik, Kenneth Aarskaug; Noack, Turid

    2011-01-01

    Artiklene i Samfunnsspeilet er tilgjengelige fra SSBs nettsider: http://www.ssb.no/ssp/ Norge og Sverige er land der samboerskap har en lang historie, og der denne samlivsformen er mest utbredt. I dag er et av fire samliv her til lands samboerskap. Men også her er det forskjeller mellom samboere og gifte. Hvis vi sammenlikner samlivskvaliteten blant samboere og gifte, finner vi at unge samboere i alderen 25 til 35 år er minst fornøyd med samlivet sitt. Samboere med planer om å gifte seg me...

  20. An automatic method to generate domain-specific investigator networks using PubMed abstracts

    Directory of Open Access Journals (Sweden)

    Gwinn Marta

    2007-06-01

    Full Text Available Abstract Background Collaboration among investigators has become critical to scientific research. This includes ad hoc collaboration established through personal contacts as well as formal consortia established by funding agencies. Continued growth in online resources for scientific research and communication has promoted the development of highly networked research communities. Extending these networks globally requires identifying additional investigators in a given domain, profiling their research interests, and collecting current contact information. We present a novel strategy for building investigator networks dynamically and producing detailed investigator profiles using data available in PubMed abstracts. Results We developed a novel strategy to obtain detailed investigator information by automatically parsing the affiliation string in PubMed records. We illustrated the results by using a published literature database in human genome epidemiology (HuGE Pub Lit as a test case. Our parsing strategy extracted country information from 92.1% of the affiliation strings in a random sample of PubMed records and in 97.0% of HuGE records, with accuracies of 94.0% and 91.0%, respectively. Institution information was parsed from 91.3% of the general PubMed records (accuracy 86.8% and from 94.2% of HuGE PubMed records (accuracy 87.0. We demonstrated the application of our approach to dynamic creation of investigator networks by creating a prototype information system containing a large database of PubMed abstracts relevant to human genome epidemiology (HuGE Pub Lit, indexed using PubMed medical subject headings converted to Unified Medical Language System concepts. Our method was able to identify 70–90% of the investigators/collaborators in three different human genetics fields; it also successfully identified 9 of 10 genetics investigators within the PREBIC network, an existing preterm birth research network. Conclusion We successfully created a

  1. Mining PubMed for Biomarker-Disease Associations to Guide Discovery

    OpenAIRE

    Jessen, Walter; Landschulz, Katherine; Turi, Thomas; Reams, Rachel

    2012-01-01

    Biomedical knowledge is growing exponentially; however, meta-knowledge around the data is often lacking. PubMed is a database comprising more than 21 million citations for biomedical literature from MEDLINE and additional life science journals dating back to the 1950s. To explore the use and frequency of biomarkers across human disease, we mined PubMed for biomarker-disease associations. We then ranked the top 100 linked diseases by relevance and mapped them to medical subject headings (MeSH)...

  2. Selvforsyning med øko-mineraler og -vitaminer

    DEFF Research Database (Denmark)

    Sehested, Jakob; Jensen, Søren Krogh; Søegaard, Karen

    2010-01-01

    Forskere ved DJF har vist, at det er muligt at opnå et tilstrækkeligt indhold af vitaminer og mineraler i foderrationen til økologiske malkekøer ved at anvende hjemmedyrkede grovfodermidler med en høj andel af mineral- og vitaminrige, grønne fodermidler. Udgivelsesdato: oktober......Forskere ved DJF har vist, at det er muligt at opnå et tilstrækkeligt indhold af vitaminer og mineraler i foderrationen til økologiske malkekøer ved at anvende hjemmedyrkede grovfodermidler med en høj andel af mineral- og vitaminrige, grønne fodermidler. Udgivelsesdato: oktober...

  3. CDAPubMed: a browser extension to retrieve EHR-based biomedical literature

    Directory of Open Access Journals (Sweden)

    Perez-Rey David

    2012-04-01

    Full Text Available Abstract Background Over the last few decades, the ever-increasing output of scientific publications has led to new challenges to keep up to date with the literature. In the biomedical area, this growth has introduced new requirements for professionals, e.g., physicians, who have to locate the exact papers that they need for their clinical and research work amongst a huge number of publications. Against this backdrop, novel information retrieval methods are even more necessary. While web search engines are widespread in many areas, facilitating access to all kinds of information, additional tools are required to automatically link information retrieved from these engines to specific biomedical applications. In the case of clinical environments, this also means considering aspects such as patient data security and confidentiality or structured contents, e.g., electronic health records (EHRs. In this scenario, we have developed a new tool to facilitate query building to retrieve scientific literature related to EHRs. Results We have developed CDAPubMed, an open-source web browser extension to integrate EHR features in biomedical literature retrieval approaches. Clinical users can use CDAPubMed to: (i load patient clinical documents, i.e., EHRs based on the Health Level 7-Clinical Document Architecture Standard (HL7-CDA, (ii identify relevant terms for scientific literature search in these documents, i.e., Medical Subject Headings (MeSH, automatically driven by the CDAPubMed configuration, which advanced users can optimize to adapt to each specific situation, and (iii generate and launch literature search queries to a major search engine, i.e., PubMed, to retrieve citations related to the EHR under examination. Conclusions CDAPubMed is a platform-independent tool designed to facilitate literature searching using keywords contained in specific EHRs. CDAPubMed is visually integrated, as an extension of a widespread web browser, within the standard

  4. Are some of the challenging aspects of the CanMEDS roles valid outside Canada?

    DEFF Research Database (Denmark)

    Ringsted, Charlotte; Hansen, Torben Lindskov; Davis, Deborah

    2006-01-01

    tasks within the roles. METHODS: We surveyed 8749 doctors within a defined region (eastern Denmark) via a single-issue, mailed questionnaire. Each of the 7 roles was represented by 3 questionnaire items to be rated for perceived importance and confidence in ability to perform the role. RESULTS......CONTEXT: Many countries have adopted the CanMEDS roles. However, there is limited information on how these apply in an international context and in different specialties. OBJECTIVES: To survey trainee and specialist ratings of the importance of the CanMEDS roles and perceived ability to perform...

  5. Factors affecting the loss of MED12-mutated leiomyoma cells during in vitro growth

    OpenAIRE

    Bloch, Jeannine; Holzmann, Carsten; Koczan, Dirk; Helmke, Burkhard Maria; Bullerdiek, J?rn

    2017-01-01

    Uterine leiomyomas (UL) are the most prevalent symptomatic human tumors at all and somatic mutations of the gene encoding mediator subcomplex 12 (MED12) constitute the most frequent driver mutations in UL. Recently, a rapid loss of mutated cells during in vitro growth of UL-derived cell cultures was reported, resulting in doubts about the benefits of UL-derived cell cultures. To evaluate if the rapid loss of MED12-mutated cells in UL cell cultures depends on in vitro passaging, we set up cell...

  6. An automatic method to generate domain-specific investigator networks using PubMed abstracts

    Science.gov (United States)

    Yu, Wei; Yesupriya, Ajay; Wulf, Anja; Qu, Junfeng; Gwinn, Marta; Khoury, Muin J

    2007-01-01

    Background Collaboration among investigators has become critical to scientific research. This includes ad hoc collaboration established through personal contacts as well as formal consortia established by funding agencies. Continued growth in online resources for scientific research and communication has promoted the development of highly networked research communities. Extending these networks globally requires identifying additional investigators in a given domain, profiling their research interests, and collecting current contact information. We present a novel strategy for building investigator networks dynamically and producing detailed investigator profiles using data available in PubMed abstracts. Results We developed a novel strategy to obtain detailed investigator information by automatically parsing the affiliation string in PubMed records. We illustrated the results by using a published literature database in human genome epidemiology (HuGE Pub Lit) as a test case. Our parsing strategy extracted country information from 92.1% of the affiliation strings in a random sample of PubMed records and in 97.0% of HuGE records, with accuracies of 94.0% and 91.0%, respectively. Institution information was parsed from 91.3% of the general PubMed records (accuracy 86.8%) and from 94.2% of HuGE PubMed records (accuracy 87.0). We demonstrated the application of our approach to dynamic creation of investigator networks by creating a prototype information system containing a large database of PubMed abstracts relevant to human genome epidemiology (HuGE Pub Lit), indexed using PubMed medical subject headings converted to Unified Medical Language System concepts. Our method was able to identify 70–90% of the investigators/collaborators in three different human genetics fields; it also successfully identified 9 of 10 genetics investigators within the PREBIC network, an existing preterm birth research network. Conclusion We successfully created a web-based prototype

  7. 14 medisinplanter fra Burma med fokus på lakserende effekt : en litteraturstudie

    OpenAIRE

    Phan, Cong Lap

    2009-01-01

    I denne masteroppgaven ble det sett på sammenhenger mellom vitenskapelige data som er tilgjengelige og bruken av 14 tradisjonelle medisinplanter, med fokus på lakserende effekt. Plantene er hentet fra Burma-samlingen som ble laget av Arnold Nordal i 1957-1961. Det ble først og fremst foretatt litteratursøk i databasene Scifinder Scholar 2007, Biological Abstract, ISI Web of Knowledge- Web of Science og PubMed. Søk på synonymnavn ble foretatt i plantedatabasene IPNI, ITIS og Tropicos....

  8. Du er god nok! Litteraturstudie om tilrettelegging av mestring for elever med dysleksi.

    OpenAIRE

    Loktu, Thea Amanda Hansen

    2017-01-01

    Bacheloroppgave, grunnskolelærerutdanning, 2017. Norsk: Temaet for oppgaven er mestring og dysleksi og omhandler hvorfor og til dels hvordan en særlig skal legge til rette for mestring hos elever med dysleksi. Oppgaven er fundert i både et samfunnsmessigperspektiv og et individperspektiv. Bacheloren søker å finne de momentene som påvirker læring for denne gruppen, med fokus på det helhetlige mennesket. Problemstillingen lyder slik: Hvorfor legge særlig til rette for mestring hos elever ...

  9. Comparison of PubMed, Scopus, Web of Science, and Google Scholar: strengths and weaknesses.

    Science.gov (United States)

    Falagas, Matthew E; Pitsouni, Eleni I; Malietzis, George A; Pappas, Georgios

    2008-02-01

    The evolution of the electronic age has led to the development of numerous medical databases on the World Wide Web, offering search facilities on a particular subject and the ability to perform citation analysis. We compared the content coverage and practical utility of PubMed, Scopus, Web of Science, and Google Scholar. The official Web pages of the databases were used to extract information on the range of journals covered, search facilities and restrictions, and update frequency. We used the example of a keyword search to evaluate the usefulness of these databases in biomedical information retrieval and a specific published article to evaluate their utility in performing citation analysis. All databases were practical in use and offered numerous search facilities. PubMed and Google Scholar are accessed for free. The keyword search with PubMed offers optimal update frequency and includes online early articles; other databases can rate articles by number of citations, as an index of importance. For citation analysis, Scopus offers about 20% more coverage than Web of Science, whereas Google Scholar offers results of inconsistent accuracy. PubMed remains an optimal tool in biomedical electronic research. Scopus covers a wider journal range, of help both in keyword searching and citation analysis, but it is currently limited to recent articles (published after 1995) compared with Web of Science. Google Scholar, as for the Web in general, can help in the retrieval of even the most obscure information but its use is marred by inadequate, less often updated, citation information.

  10. Involverende undervisning med web- og SMS-baseret Student Response Systems

    DEFF Research Database (Denmark)

    Kjær, Christopher; Larsen, Søren

    underviseren kan stille spørgsmål til de studerende i undervisningslokalet og med det samme se, hvad de studerende har svaret. Den studerende svarer via sin mobiltelefon, tablet eller bærbare PC. Aktiviteter 1. Introduktion til SRS – pædagogikken og mulighederne 2. Cases på konkret brug af SRS fra SDU og KU 3...

  11. MED12 exon 2 mutations in phyllodes tumors of the breast

    International Nuclear Information System (INIS)

    Nagasawa, Satoi; Maeda, Ichiro; Fukuda, Takayo; Wu, Wenwen; Hayami, Ryosuke; Kojima, Yasuyuki; Tsugawa, Ko-ichiro; Ohta, Tomohiko

    2015-01-01

    Exon 2 of MED12, a subunit of the transcriptional mediator complex, has been frequently mutated in uterine leiomyomas and breast fibroadenomas; however, it has been rarely mutated in other tumors. Although the mutations were also found in uterine leiomyosarcomas, the frequency was significantly lower than in uterine leiomyomas. Here, we examined the MED12 mutation in phyllodes tumors, another biphasic tumor with epithelial and stromal components related to breast fibroadenomas. Mutations in MED12 exon 2 were analyzed in nine fibroadenomas and eleven phyllodes tumors via Sanger sequencing. A panel of cancer- and sarcoma-related genes was also analyzed using Ion Torrent next-generation sequencing. Six mutations in fibroadenomas, including those previously reported (6/9, 67%), and five mutations in phyllodes tumors (5/11, 45%) were observed. Three mutations in the phyllodes tumors were missense mutations at Gly44, which is common in uterine leiomyomas and breast fibroadenomas. In addition, two deletion mutations (in-frame c.133-144del12 and loss of splice acceptor c.100-68-137del106) were observed in the phyllodes tumors. No other recurrent mutation was observed with next-generation sequencing. Frequent mutations in MED12 exon 2 in the phyllodes tumors suggest that it may share genetic etiology with uterine leiomyoma, a subgroup of uterine leiomyosarcomas and breast fibroadenoma

  12. Hvad er smag, og hvordan underviser man i og med smag?

    DEFF Research Database (Denmark)

    Qvortrup, Lars; Wistoft, Karen

    2017-01-01

    Hvad er smag, og hvordan underviser man i smag som undervisningens genstand eller med smag som et virkemiddel i undervisningen? Det er denne artikels to hovedspørgsmål. Formålet er at præsentere det, der kaldes en smagsdidaktisk refleksionsteori, dvs. en teori der reflekterer over, hvordan man un...

  13. 59 forskellige kronikker, klummer mv. med hver deres titel i Berlingske, JP og Kristeligt Dagblad

    DEFF Research Database (Denmark)

    Sørensen, Lars Hovbakke

    2017-01-01

    og julemiddagen Den 16. december: Julens sange Den 17. december: Julebukken Den 18. december: ”Rudolf med den røde tud” Den 19. december: Kravlenisserne Den 20. december: Glöggen og juleøllet Den 21. december: Adventsstjernen Den 22. december: Julemarkedet Den 23. december: Walt Disneys juleshow Den...

  14. Kommunernes arbejde med sundhedsfremme og bæredygtig udvikling i relation til folkeskolen

    DEFF Research Database (Denmark)

    Nordin, Lone Lindegard; Madsen, Katrine Dahl; Andersen, Tanja Thinggaard

    Denne rapport præsenterer en landsdækkende undersøgelse af kommunernes arbejde med sundhedsfremme og bæredygtig udvikling i relation til folkeskolen. Undersøgelsen er udført i efteråret 2013 i Forskningscenter for sundhedsfremmende bæredygtig skoleudvikling ved DPU, Aarhus Universitet. Formålet m...

  15. Velfærdsteknologi og læringsteknologi med MOOC som eksempel

    DEFF Research Database (Denmark)

    Helms, Niels Henrik; Heilesen, Simon

    2015-01-01

    Kapitlet redegører for ‘Velfærdsteknologi’ i forhold til begrebet 'læringsteknologi’. Læringsteknologi bestemmes som velfærdsteknologi udfoldet inden for uddannelsessystemet. Ligesom velfærdsteknologi indføres læringsteknologi med multiple dagsordener, hvor hensigterne både er at tilskynde den læ...

  16. Integrated and implicit : how residents learn CanMEDS roles by participating in practice

    NARCIS (Netherlands)

    Renting, Nienke; Raat, A N Janet; Dornan, Tim; Wenger-Trayner, Etienne; van der Wal, Martha A; Borleffs, Jan C C; Gans, Rijk O B; Jaarsma, A Debbie C

    CONTEXT: Learning outcomes for residency training are defined in competency frameworks such as the CanMEDS framework, which ultimately aim to better prepare residents for their future tasks. Although residents' training relies heavily on learning through participation in the workplace under the

  17. Med H.C. Andersen i Portugal år 1866

    DEFF Research Database (Denmark)

    Skousbøll, Karin

    2004-01-01

    ankomst med diligence fra Spanien ind over fastlandet til Lissabon, men også rundt i byen, i omegnen og til havnebyen Setubal. Det indsamlede billedstof som underbygger teksten er dels historisk stof indhentet fra Det kg. Bibliotek o.a. kilder og dels fremskaffet fra Portugals arkiver og de respektive...

  18. Udvikling af informationskompetence i problemorienteret arbejde med brug af digitale værktøjer

    DEFF Research Database (Denmark)

    Nielsen, Jørgen Lerche; Birch Andreasen, Lars; Jørgensen, Lars

    2006-01-01

    vejledningsformer. Visionen for projektet er, at arbejdet med at støtte de studerendes udvikling af informationskompetence ikke alene ses som en opgave for biblioteker biblioteker, men som en opgave der skal løses i et tættere integreret samarbejde mellem biblioteker og faglige uddannelsesmiljøer. Pilotprojektet...

  19. The 11th Annual Mediterranean Ad Hoc Networking Workshop (Med-Hoc-Net 2012)

    NARCIS (Netherlands)

    Pitsillides, A.; Douligeris, C.; Vassiliou, V.; Heijenk, Geert; Cavalcante de Oliveira, J.

    Message from the General Chairs Welcome to the 2012 Mediterranean Ad Hoc Networking Workshop in Ayia Napa, Cyprus. We are excited to host Med-Hoc-Net. As a major annual international workshop, following recent successful workshops in Sicily (2006), Corfu (2007), Palma de Mallorca (2008), Haifa

  20. Information architecture: study and analysis of data Public Medical base (PubMed

    Directory of Open Access Journals (Sweden)

    Odete Máyra Mesquita Sales

    2016-07-01

    Full Text Available Objective. Based on principles proposed by Rosenfeld and Morville (2006, the present study examined the PubMed database interface, since a well-structured information architecture contributes to good usability in any digital environment. Method. The research development occurred through the use of literature techniques and empirical study on the analysis of information architecture based on organization, navigation, recommended labeling and search for Rosenfeld and Morville (2006 for the sake of usability base PubMed. For better understanding and description of these principles, we used the technique of content analysis. Results. The results showed that the database interface meets the criteria established by the elements of Information Architecture, such as organization based on hypertext structure, horizontal menu and local content divided into categories, identifying active links, global navigation , breadcrumb, textual labeling and iconographic and highlight the search engine. Conclusions. This research showed that the PubMed database interface is well structured, friendly and objective, with numerous possibilities of search and information retrieval. However, there is a need to adopt accessibility standards on this website, so that it reaches more efficiently its purpose of facilitating access to information organized and stored in the PubMed database.