Lashkari, Bahman; Mandelis, Andreas
2011-09-01
In this work, a detailed theoretical and experimental comparison between various key parameters of the pulsed and frequency-domain (FD) photoacoustic (PA) imaging modalities is developed. The signal-to-noise ratios (SNRs) of these methods are theoretically calculated in terms of transducer bandwidth, PA signal generation physics, and laser pulse or chirp parameters. Large differences between maximum (peak) SNRs were predicted. However, it is shown that in practice the SNR differences are much smaller. Typical experimental SNRs were 23.2 dB and 26.1 dB for FD-PA and time-domain (TD)-PA peak responses, respectively, from a subsurface black absorber. The SNR of the pulsed PA can be significantly improved with proper high-pass filtering of the signal, which minimizes but does not eliminate baseline oscillations. On the other hand, the SNR of the FD method can be enhanced substantially by increasing laser power and decreasing chirp duration (exposure) correspondingly, so as to remain within the maximum permissible exposure guidelines. The SNR crossover chirp duration is calculated as a function of transducer bandwidth and the conditions yielding higher SNR for the FD mode are established. Furthermore, it was demonstrated that the FD axial resolution is affected by both signal amplitude and limited chirp bandwidth. The axial resolution of the pulse is, in principle, superior due to its larger bandwidth; however, the bipolar shape of the signal is a drawback in this regard. Along with the absence of baseline oscillation in cross-correlation FD-PA, the FD phase signal can be combined with the amplitude signal to yield better axial resolution than pulsed PA, and without artifacts. The contrast of both methods is compared both in depth-wise (delay-time) and fixed delay time images. It was shown that the FD method possesses higher contrast, even after contrast enhancement of the pulsed response through filtering.
The optimal polarizations for achieving maximum contrast in radar images
Swartz, A. A.; Yueh, H. A.; Kong, J. A.; Novak, L. M.; Shin, R. T.
1988-01-01
There is considerable interest in determining the optimal polarizations that maximize contrast between two scattering classes in polarimetric radar images. A systematic approach is presented for obtaining the optimal polarimetric matched filter, i.e., that filter which produces maximum contrast between two scattering classes. The maximization procedure involves solving an eigenvalue problem where the eigenvector corresponding to the maximum contrast ratio is an optimal polarimetric matched filter. To exhibit the physical significance of this filter, it is transformed into its associated transmitting and receiving polarization states, written in terms of horizontal and vertical vector components. For the special case where the transmitting polarization is fixed, the receiving polarization which maximizes the contrast ratio is also obtained. Polarimetric filtering is then applies to synthetic aperture radar images obtained from the Jet Propulsion Laboratory. It is shown, both numerically and through the use of radar imagery, that maximum image contrast can be realized when data is processed with the optimal polarimeter matched filter.
Experimental study on prediction model for maximum rebound ratio
LEI Wei-dong; TENG Jun; A.HEFNY; ZHAO Jian; GUAN Jiong
2007-01-01
The proposed prediction model for estimating the maximum rebound ratio was applied to a field explosion test, Mandai test in Singapore.The estimated possible maximum Deak particle velocities(PPVs)were compared with the field records.Three of the four available field-recorded PPVs lie exactly below the estimated possible maximum values as expected.while the fourth available field-recorded PPV lies close to and a bit higher than the estimated maximum possible PPV The comparison results show that the predicted PPVs from the proposed prediction model for the maximum rebound ratio match the field.recorded PPVs better than those from two empirical formulae.The very good agreement between the estimated and field-recorded values validates the proposed prediction model for estimating PPV in a rock mass with a set of ipints due to application of a two dimensional compressional wave at the boundary of a tunnel or a borehole.
Dual energy contrast enhanced breast imaging optimization using contrast to noise ratio
Arvanitis, C. D.; Royle, G.; Speller, R.
2007-03-01
The properties of dual energy contrast enhanced breast imaging have been analyzed by imaging a 4 cm breast equivalent phantom consisting of adipose and glandular equivalent plastics. This phantom had superimposed another thin plastic which incorporated a 2 mm deep cylinder filled with iodinated contrast media. The iodine projected thicknesses used for this study was 3 mg/cm2. Low and high energy spectra that straddle the iodine K-edge were used. Critical parameters such as the energy spectra and exposure are discussed, along with post processing by means of nonlinear energy dependent function. The dual energy image was evaluated using the relative contrast to noise ratio of a 2.5 mm x 2.5 mm region of the image at the different iodine concentrations incorporating different breast composition with respect to the noniodinated areas. Optimum results were achieved when the low and high-energy images were used in such a way that relative contrast to noise ratio of the iodine with respect to the background tissue was maximum. A figure of merit suggests that higher noise levels can be tolerated at the benefit of lower exposure. Contrast media kinetics of a phantom incorporating a water flow of 20.4 ml/min through the plastic cylinder suggests that time domain imaging could be performed with this approach. The results suggest that optimization of dual energy contrast enhanced mammography has the potential to lead to the development of perfusion digital mammography.
Maximum likelihood estimation for semiparametric density ratio model.
Diao, Guoqing; Ning, Jing; Qin, Jing
2012-06-27
In the statistical literature, the conditional density model specification is commonly used to study regression effects. One attractive model is the semiparametric density ratio model, under which the conditional density function is the product of an unknown baseline density function and a known parametric function containing the covariate information. This model has a natural connection with generalized linear models and is closely related to biased sampling problems. Despite the attractive features and importance of this model, most existing methods are too restrictive since they are based on multi-sample data or conditional likelihood functions. The conditional likelihood approach can eliminate the unknown baseline density but cannot estimate it. We propose efficient estimation procedures based on the nonparametric likelihood. The nonparametric likelihood approach allows for general forms of covariates and estimates the regression parameters and the baseline density simultaneously. Therefore, the nonparametric likelihood approach is more versatile than the conditional likelihood approach especially when estimation of the conditional mean or other quantities of the outcome is of interest. We show that the nonparametric maximum likelihood estimators are consistent, asymptotically normal, and asymptotically efficient. Simulation studies demonstrate that the proposed methods perform well in practical settings. A real example is used for illustration.
Contrast-to-noise ratio optimization for a prototype phase-contrast computed tomography scanner
Müller, Mark, E-mail: mark-mueller@ph.tum.de; Yaroshenko, Andre; Velroyen, Astrid; Tapfer, Arne [Lehrstuhl für Biomedizinische Physik, Physik-Department & Institut für Medizintechnik, Technische Universität München, 85748 Garching (Germany); Bech, Martin [Medical Radiation Physics, Lund University, Barngatan 2:1, 221 85 Lund (Sweden); Pauwels, Bart; Bruyndonckx, Peter; Sasov, Alexander [Bruker microCT, Kartuizersweg 3B, B-2550 Kontich (Belgium); Pfeiffer, Franz [Lehrstuhl für Biomedizinische Physik, Physik-Department & Institut für Medizintechnik, Technische Universität München, 85748 Garching (Germany); Institut für diagnostische und interventionelle Radiologie, Klinikum rechts der Isar, Technische Universität München, 81675 München (Germany); Institute for Advanced Study, Technische Universität München, 85748 Garching (Germany)
2015-12-15
In the field of biomedical X-ray imaging, novel techniques, such as phase-contrast and dark-field imaging, have the potential to enhance the contrast and provide complementary structural information about a specimen. In this paper, a first prototype of a preclinical X-ray phase-contrast CT scanner based on a Talbot-Lau interferometer is characterized. We present a study of the contrast-to-noise ratios for attenuation and phase-contrast images acquired with the prototype scanner. The shown results are based on a series of projection images and tomographic data sets of a plastic phantom in phase and attenuation-contrast recorded with varying acquisition settings. Subsequently, the signal and noise distribution of different regions in the phantom were determined. We present a novel method for estimation of contrast-to-noise ratios for projection images based on the cylindrical geometry of the phantom. Analytical functions, representing the expected signal in phase and attenuation-contrast for a circular object, are fitted to individual line profiles of the projection data. The free parameter of the fit function is used to estimate the contrast and the goodness of the fit is determined to assess the noise in the respective signal. The results depict the dependence of the contrast-to-noise ratios on the applied source voltages, the number of steps of the phase stepping routine, and the exposure times for an individual step. Moreover, the influence of the number of projection angles on the image quality of CT slices is investigated. Finally, the implications for future imaging purposes with the scanner are discussed.
Contrast-to-noise ratio optimization for a prototype phase-contrast computed tomography scanner.
Müller, Mark; Yaroshenko, Andre; Velroyen, Astrid; Bech, Martin; Tapfer, Arne; Pauwels, Bart; Bruyndonckx, Peter; Sasov, Alexander; Pfeiffer, Franz
2015-12-01
In the field of biomedical X-ray imaging, novel techniques, such as phase-contrast and dark-field imaging, have the potential to enhance the contrast and provide complementary structural information about a specimen. In this paper, a first prototype of a preclinical X-ray phase-contrast CT scanner based on a Talbot-Lau interferometer is characterized. We present a study of the contrast-to-noise ratios for attenuation and phase-contrast images acquired with the prototype scanner. The shown results are based on a series of projection images and tomographic data sets of a plastic phantom in phase and attenuation-contrast recorded with varying acquisition settings. Subsequently, the signal and noise distribution of different regions in the phantom were determined. We present a novel method for estimation of contrast-to-noise ratios for projection images based on the cylindrical geometry of the phantom. Analytical functions, representing the expected signal in phase and attenuation-contrast for a circular object, are fitted to individual line profiles of the projection data. The free parameter of the fit function is used to estimate the contrast and the goodness of the fit is determined to assess the noise in the respective signal. The results depict the dependence of the contrast-to-noise ratios on the applied source voltages, the number of steps of the phase stepping routine, and the exposure times for an individual step. Moreover, the influence of the number of projection angles on the image quality of CT slices is investigated. Finally, the implications for future imaging purposes with the scanner are discussed.
Measurement of Contrast Ratios for 3D Display
2000-07-01
stereoscopic, autostereoscopic , 3D , display ABSTRACT 3D image display devices have wide applications in medical and entertainment areas. Binocular (stereoscopic...and system crosstalk. In many 3D display systems viewer’ crosstalk is an important issue for good performance, especial in autostereoscopic display...UNCLASSIFIED Defense Technical Information Center Compilation Part Notice ADPO 11343 TITLE: Measurement of Contrast Ratios for 3D Display
Ertas, Gokhan; Gulcur, H Ozcan; Tunaci, Mehtap
2008-05-01
Effectiveness of morphological descriptors based on normalized maximum intensity-time ratio (nMITR) maps generated using a 3 x 3 pixel moving mask on dynamic contrast-enhanced magnetoresistance (MR) mammograms are studied for assessment of malignancy. After a rough indication of volume of interest on the nMITR maps, lesions are automatically segmented. Two-dimensional (2D) convexity, normalized complexity, extent, and eccentricity as well as three-dimensional (3D) versions of these descriptors and contact surface area ratio are computed. On a data set consisting of dynamic contrast-enhanced MR DCE-MR mammograms from 51 women that contain 26 benign and 32 malignant lesions, 3D convexity, complexity, and extent are found to reflect aggressiveness of malignancy better than 2D descriptors. Contact surface area ratio which is easily adaptable to different imaging resolutions is found to be the most significant and accurate descriptor (75% sensitivity, 88% specificity, 89% positive predictive values, and 74% negative predictive values).
30 CFR 7.87 - Test to determine the maximum fuel-air ratio.
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Test to determine the maximum fuel-air ratio. 7... Use in Underground Coal Mines § 7.87 Test to determine the maximum fuel-air ratio. (a) Test procedure... several speed/torque conditions to determine the concentrations of CO and NOX, dry basis, in the...
Effect of consolidation ratios on maximum dynamic shear modulus of sands
Yuan Xiaoming; Sun Jing; Sun Rui
2005-01-01
The dynamic shear modulus (DSM) is the most basic soil parameter in earthquake or other dynamic loading conditions and can be obtained through testing in the field or in the laboratory. The effect of consolidation ratios on the maximum DSM for two types of sand is investigated by using resonant column tests. And, an increment formula to obtain the maximum DSM for cases of consolidation ratio kc＞1 is presented. The results indicate that the maximum DSM rises rapidly when kc is near 1 and then slows down, which means that the power function of the consolidation ratio increment kc-1 can be used to describe the variation of the maximum DSM due to kc＞1. The results also indicate that the increase in the maximum DSM due to kc＞1 is significantly larger than that predicted by Hardin and Black's formula.
Fungal/bacterial ratios in grassland with contrasting nitrogen management
Vries, de F.T.; Hoffland, E.; Eekeren, van N.J.M.; Brussaard, L.; Bloem, J.
2006-01-01
It is frequently hypothesised that high soil fungal/bacterial ratios are indicative for more sustainable agricultural systems. Increased F / B ratios have been reported in extensively managed grasslands. To determine the shifts in fungal/bacterial biomass ratio as influenced by grassland management
Ultrasonic Imaging Using a Flexible Array: Improvements to the Maximum Contrast Autofocus Algorithm
Hunter, A. J.; Drinkwater, B. W.; Wilcox, P. D.
2009-03-01
In previous work, we have presented the maximum contrast autofocus algorithm for estimating unknown imaging parameters, e.g., for imaging through complicated surfaces using a flexible ultrasonic array. This paper details recent improvements to the algorithm. The algorithm operates by maximizing the image contrast metric with respect to the imaging parameters. For a flexible array, the relative positions of the array elements are parameterized using a cubic spline function and the spline control points are estimated by iterative maximisation of the image contrast via simulated annealing. The resultant spline gives an estimate of the array geometry and the profile of the surface that it has conformed to, allowing the generation of a well-focused image. A pre-processing step is introduced to obtain an initial estimate of the array geometry, reducing the time taken for the algorithm to convergence. Experimental results are demonstrated using a flexible array prototype.
Maximum Deformation Ratio of Droplets of Water-Based Paint Impact on a Flat Surface
Weiwei Xu
2017-06-01
Full Text Available In this research, the maximum deformation ratio of water-based paint droplets impacting and spreading onto a flat solid surface was investigated numerically based on the Navier–Stokes equation coupled with the level set method. The effects of droplet size, impact velocity, and equilibrium contact angle are taken into account. The maximum deformation ratio increases as droplet size and impact velocity increase, and can scale as We1/4, where We is the Weber number, for the case of the effect of the droplet size. Finally, the effect of equilibrium contact angle is investigated, and the result shows that spreading radius decreases with the increase in equilibrium contact angle, whereas the height increases. When the dimensionless time t* < 0.3, there is a linear relationship between the dimensionless spreading radius and the dimensionless time to the 1/2 power. For the case of 80° ≤ θe ≤ 120°, where θe is the equilibrium contact angle, the simulation result of the maximum deformation ratio follows the fitting result. The research on the maximum deformation ratio of water-based paint is useful for water-based paint applications in the automobile industry, as well as in the biomedical industry and the real estate industry. Please check all the part in the whole passage that highlighted in blue whether retains meaning before.
GUAN Hsin; WANG Bo; LU Pingping; XU Liang
2014-01-01
The identification of maximum road friction coefficient and optimal slip ratio is crucial to vehicle dynamics and control. However, it is always not easy to identify the maximum road friction coefficient with high robustness and good adaptability to various vehicle operating conditions. The existing investigations on robust identification of maximum road friction coefficient are unsatisfactory. In this paper, an identification approach based on road type recognition is proposed for the robust identification of maximum road friction coefficient and optimal slip ratio. The instantaneous road friction coefficient is estimated through the recursive least square with a forgetting factor method based on the single wheel model, and the estimated road friction coefficient and slip ratio are grouped in a set of samples in a small time interval before the current time, which are updated with time progressing. The current road type is recognized by comparing the samples of the estimated road friction coefficient with the standard road friction coefficient of each typical road, and the minimum statistical error is used as the recognition principle to improve identification robustness. Once the road type is recognized, the maximum road friction coefficient and optimal slip ratio are determined. The numerical simulation tests are conducted on two typical road friction conditions(single-friction and joint-friction) by using CarSim software. The test results show that there is little identification error between the identified maximum road friction coefficient and the pre-set value in CarSim. The proposed identification method has good robustness performance to external disturbances and good adaptability to various vehicle operating conditions and road variations, and the identification results can be used for the adjustment of vehicle active safety control strategies.
Pysz, Marybeth A.; Foygel, Kira; Panje, Cedric M.; Needles, Andrew; Tian, Lu; Willmann, Jürgen K.
2015-01-01
Objectives Contrast-enhanced ultrasound imaging is increasingly being used in the clinic for assessment of tissue vascularity. The purpose of our study was to evaluate the effect of different contrast administration parameters on the in vivo ultrasound imaging signal in tumor-bearing mice using a maximum intensity persistence (MIP) algorithm and to evaluate the reliability of in vivo MIP imaging in assessing tumor vascularity. The potential of in vivo MIP imaging for monitoring tumor vascularity during antiangiogenic cancer treatment was further evaluated. Materials and Methods In intraindividual experiments, varying contrast microbubble concentrations (5 × 105, 5 × 106, 5 × 107, 5 × 108 microbubbles in 100 µL saline) and contrast injection rates (0.6, 1.2, and 2.4 mL/min) in subcutaneous tumor-bearing mice were applied and their effects on in vivo contrast-enhanced ultrasound MIP imaging plateau values were obtained using a dedicated small animal ultrasound imaging system (40 MHz). Reliability of MIP ultrasound imaging was tested following 2 injections of the same micro-bubble concentration (5 × 107 microbubbles at 1.2 mL/min) in the same tumors. In mice with subcutaneous human colon cancer xenografts, longitudinal contrast-enhanced ultrasound MIP imaging plateau values (baseline and at 48 hours) were compared between mice with and without antiangiogenic treatment (anti-vascular endothelial growth factor antibody). Ex vivo CD31 immunostaining of tumor tissue was used to correlate in vivo MIP imaging plateau values with microvessel density analysis. Results In vivo MIP imaging plateau values correlated significantly (P = 0.001) with contrast microbubble doses. At 3 different injection rates of 0.6, 1.2, and 2.4 mL/min, MIP imaging plateau values did not change significantly (P = 0.61). Following 2 injections with the same microbubble dose and injection rate, MIP imaging plateau values were obtained with high reliability with an intraclass correlation
Zhang, H X
2008-01-01
An innovative approach for total maximum daily load (TMDL) allocation and implementation is the watershed-based pollutant trading. Given the inherent scientific uncertainty for the tradeoffs between point and nonpoint sources, setting of trading ratios can be a contentious issue and was already listed as an obstacle by several pollutant trading programs. One of the fundamental reasons that a trading ratio is often set higher (e.g. greater than 2) is to allow for uncertainty in the level of control needed to attain water quality standards, and to provide a buffer in case traded reductions are less effective than expected. However, most of the available studies did not provide an approach to explicitly address the determination of trading ratio. Uncertainty analysis has rarely been linked to determination of trading ratio.This paper presents a practical methodology in estimating "equivalent trading ratio (ETR)" and links uncertainty analysis with trading ratio determination from TMDL allocation process. Determination of ETR can provide a preliminary evaluation of "tradeoffs" between various combination of point and nonpoint source control strategies on ambient water quality improvement. A greater portion of NPS load reduction in overall TMDL load reduction generally correlates with greater uncertainty and thus requires greater trading ratio. The rigorous quantification of trading ratio will enhance the scientific basis and thus public perception for more informed decision in overall watershed-based pollutant trading program.
Optimum air-demand ratio for maximum aeration efficiency in high-head gated circular conduits.
Ozkan, Fahri; Tuna, M Cihat; Baylar, Ahmet; Ozturk, Mualla
2014-01-01
Oxygen is an important component of water quality and its ability to sustain life. Water aeration is the process of introducing air into a body of water to increase its oxygen saturation. Water aeration can be accomplished in a variety of ways, for instance, closed-conduit aeration. High-speed flow in a closed conduit involves air-water mixture flow. The air flow results from the subatmospheric pressure downstream of the gate. The air entrained by the high-speed flow is supplied by the air vent. The air entrained into the flow in the form of a large number of bubbles accelerates oxygen transfer and hence also increases aeration efficiency. In the present work, the optimum air-demand ratio for maximum aeration efficiency in high-head gated circular conduits was studied experimentally. Results showed that aeration efficiency increased with the air-demand ratio to a certain point and then aeration efficiency did not change with a further increase of the air-demand ratio. Thus, there was an optimum value for the air-demand ratio, depending on the Froude number, which provides maximum aeration efficiency. Furthermore, a design formula for aeration efficiency was presented relating aeration efficiency to the air-demand ratio and Froude number.
Sparse maximum harmonics-to-noise-ratio deconvolution for weak fault signature detection in bearings
Miao, Yonghao; Zhao, Ming; Lin, Jing; Xu, Xiaoqiang
2016-10-01
De-noising and enhancement of the weak fault signature from the noisy signal are crucial for fault diagnosis, as features are often very weak and masked by the background noise. Deconvolution methods have a significant advantage in counteracting the influence of the transmission path and enhancing the fault impulses. However, the performance of traditional deconvolution methods is greatly affected by some limitations, which restrict the application range. Therefore, this paper proposes a new deconvolution method, named sparse maximum harmonics-noise-ratio deconvolution (SMHD), that employs a novel index, the harmonics-to-noise ratio (HNR), to be the objective function for iteratively choosing the optimum filter coefficients to maximize HNR. SMHD is designed to enhance latent periodic impulse faults from heavy noise signals by calculating the HNR to estimate the period. A sparse factor is utilized to further suppress the noise and improve the signal-to-noise ratio of the filtered signal in every iteration step. In addition, the updating process of the sparse threshold value and the period guarantees the robustness of SMHD. On this basis, the new method not only overcomes the limitations associated with traditional deconvolution methods, minimum entropy deconvolution (MED) and maximum correlated kurtosis deconvolution (MCKD), but visual inspection is also better, even if the fault period is not provided in advance. Moreover, the efficiency of the proposed method is verified by simulations and bearing data from different test rigs. The results show that the proposed method is effective in the detection of various bearing faults compared with the original MED and MCKD.
Describing Adequacy of cure with maximum hardness ratios and non-linear regression.
Bouschlicher, Murray; Berning, Kristen; Qian, Fang
2008-01-01
Knoop Hardness (KH) ratios (HR) > or = 80% are commonly used as criteria for the adequate cure of a composite. These per-specimen HRs can be misleading, as both numerator and denominator may increase concurrently, prior to reaching an asymptotic, top-surface maximum hardness value (H(MAX)). Extended cure times were used to establish H(MAX) and descriptive statistics, and non-linear regression analysis were used to describe the relationship between exposure duration and HR and predict the time required for HR-H(MAX) = 80%. Composite samples 2.00 x 5.00 mm diameter (n = 5/grp) were cured for 10 seconds, 20 seconds, 40 seconds, 60 seconds, 90 seconds, 120 seconds, 180 seconds and 240 seconds in a 2-composite x 2-light curing unit design. A microhybrid (Point 4, P4) or microfill resin (Heliomolar, HM) composite was cured with a QTH or LED light curing unit and then stored in the dark for 24 hours prior to KH testing. Non-linear regression was calculated with: H = (H(MAX)-c)(1-e(-kt)) +c, H(MAX) = maximum hardness (a theoretical asymptotic value), c = constant (t = 0), k = rate constant and t = exposure duration describes the relationship between radiant exposure (irradiance x time) and HRs. Exposure durations for HR-H(MAX) = 80% were calculated. Two-sample t-tests for pairwise comparisons evaluated relative performance of the light curing units for similar surface x composite x exposure (10-90s). A good measure of goodness-of-fit of the non-linear regression, r2, ranged from 0.68-0.95. (mean = 0.82). Microhybrid (P4) exposure to achieve HR-H(MAX = 80% was 21 seconds for QTH and 34 seconds for the LED light curing unit. Corresponding values for microfill (HM) were 71 and 74 seconds, respectively. P4 HR-H(MAX) of LED vs QTH was statistically similar for 10 to 40 seconds, while HM HR-H(MAX) of LED was significantly lower than QTH for 10 to 40 seconds. It was concluded that redefined hardness ratios based on maximum hardness used in conjunction with non-linear regression
Li, Xin; Huang, Wei; Rooney, William D
2012-11-01
With advances in magnetic resonance imaging (MRI) technology, dynamic contrast-enhanced (DCE)-MRI is approaching the capability to simultaneously deliver both high spatial and high temporal resolutions for clinical applications. However, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) considerations and their impacts regarding pharmacokinetic modeling of the time-course data continue to represent challenges in the design of DCE-MRI acquisitions. Given that many acquisition parameters can affect the nature of DCE-MRI data, minimizing tissue-specific data acquisition discrepancy (among sites and scanner models) is as important as synchronizing pharmacokinetic modeling approaches. For cancer-related DCE-MRI studies where rapid contrast reagent (CR) extravasation is expected, current DCE-MRI protocols often adopt a three-dimensional fast low-angle shot (FLASH) sequence to achieve spatial-temporal resolution requirements. Based on breast and prostate DCE-MRI data acquired with different FLASH sequence parameters, this paper elucidates a number of SNR and CNR considerations for acquisition optimization and pharmacokinetic modeling implications therein. Simulations based on region of interest data further indicate that the effects of intercompartmental water exchange often play an important role in DCE time-course data modeling, especially for protocols optimized for post-CR SNR.
Impact and Mitigation of Multiantenna Analog Front-End Mismatch in Transmit Maximum Ratio Combining
Liu, Jian; Khaled, Nadia; Petré, Frederik; Bourdoux, André; Barel, Alain
2006-12-01
Transmit maximum ratio combining (MRC) allows to extend the range of wireless local area networks (WLANs) by exploiting spatial diversity and array gains. These gains, however, depend on the availability of the channel state information (CSI). In this perspective, an open-loop approach in time-division-duplex (TDD) systems relies on channel reciprocity between up- and downlink to acquire the CSI. Although the propagation channel can be assumed to be reciprocal, the radio-frequency (RF) transceivers may exhibit amplitude and phase mismatches between the up- and downlink. In this contribution, we present a statistical analysis to assess the impact of these mismatches on the performance of transmit-MRC. Furthermore, we propose a novel mixed-signal calibration scheme to mitigate these mismatches, which allows to reduce the implementation loss to as little as a few tenths of a dB. Finally, we also demonstrate the feasibility of the proposed calibration scheme in a real-time wireless MIMO-OFDM prototyping platform.
Overlap maximum matching ratio (OMMR)：a new measure to evaluate overlaps of essential modules
Xiao-xia ZHANG; Qiang-hua XIAO; Bin LI; Sai HU; Hui-jun XIONG; Bi-hai ZHAO
2015-01-01
Protein complexes are the basic units of macro-molecular organizations and help us to understand the cell’s mechanism. The development of the yeast two-hybrid, tandem affinity purification, and mass spectrometry high-throughput proteomic techniques supplies a large amount of protein-protein interaction data, which make it possible to predict overlapping complexes through computational methods. Research shows that overlapping complexes can contribute to identifying essential proteins, which are necessary for the organism to survive and reproduce, and for life’s activities. Scholars pay more attention to the evaluation of protein complexes. However, few of them focus on predicted overlaps. In this paper, an evaluation criterion called overlap maximum matching ratio (OMMR) is proposed to analyze the similarity between the identified overlaps and the benchmark overlap modules. Comparison of essential proteins and gene ontology (GO) analysis are also used to assess the quality of overlaps. We perform a comprehensive comparison of serveral overlapping complexes prediction approaches, using three yeast protein-protein interaction (PPI) networks. We focus on the analysis of overlaps identified by these algorithms. Experimental results indicate the important of overlaps and reveal the relationship between overlaps and identification of essential proteins.
Arbutina Bojan
2011-01-01
Full Text Available AM CVn-type stars and ultra-compact X-ray binaries are extremely interesting semi-detached close binary systems in which the Roche lobe filling component is a white dwarf transferring mass to another white dwarf, neutron star or a black hole. Earlier theoretical considerations show that there is a maximum mass ratio of AM CVn-type binary systems (qmax ≈ 2/3 below which the mass transfer is stable. In this paper we derive slightly different value for qmax and more interestingly, by applying the same procedure, we find the maximum expected white dwarf mass in ultra-compact X-ray binaries.
Practical method and device for enhancing pulse contrast ratio for lasers and electron accelerators
Zhang, Shukui; Wilson, Guy
2014-09-23
An apparatus and method for enhancing pulse contrast ratios for drive lasers and electron accelerators. The invention comprises a mechanical dual-shutter system wherein the shutters are placed sequentially in series in a laser beam path. Each shutter of the dual shutter system has an individually operated trigger for opening and closing the shutter. As the triggers are operated individually, the delay between opening and closing first shutter and opening and closing the second shutter is variable providing for variable differential time windows and enhancement of pulse contrast ratio.
Optical design for excellent contrast ratio in a reflective horizontal-switching liquid crystal cell
Kim, Kyung-Mi; Ji, Seung-Hoon; Lee, Gi-Dong [Department of Electronics Engineering, Dong-A University, Busan 604-714 (Korea, Republic of); Lee, Joun-Ho [LG.Philips LCD, 642-3 Jinpyung-dong, Gumi-city, Kyungbuk 730-350 (Korea, Republic of); Lee, Seung Hee [Research Center for Advanced Materials Development, School of Advanced Materials Engineering, Chonbuk National University, Chonju, Chonbuk 561-756 (Korea, Republic of)], E-mail: gdlee@dau.ac.kr, E-mail: lsh1@chonbuk.ac.kr
2008-06-07
In this paper, we propose an optical configuration for a reflective liquid crystal (LC) cell with a single polarizer that can show an excellent contrast ratio by effectively eliminating phase dispersion. The proposed configuration consists of a half-wave retarder, two A-plates, a quarter-wave LC cell and a reflector; the configuration was designed on a Poincare sphere with the trigonometric method. From the calculation, we confirm that this configuration can show a high contrast ratio as compared with the conventional configuration due to the excellent dark state.
Body Fineness Ratio as a Predictor of Maximum Prolonged-Swimming Speed in Coral Reef Fishes
Walker, Jeffrey A.; Alfaro, Michael E.; Noble, Mae M.; Fulton, Christopher J.
2013-01-01
The ability to sustain high swimming speeds is believed to be an important factor affecting resource acquisition in fishes. While we have gained insights into how fin morphology and motion influences swimming performance in coral reef fishes, the role of other traits, such as body shape, remains poorly understood. We explore the ability of two mechanistic models of the causal relationship between body fineness ratio and endurance swimming-performance to predict maximum prolonged-swimming speed (Umax) among 84 fish species from the Great Barrier Reef, Australia. A drag model, based on semi-empirical data on the drag of rigid, submerged bodies of revolution, was applied to species that employ pectoral-fin propulsion with a rigid body at Umax. An alternative model, based on the results of computer simulations of optimal shape in self-propelled undulating bodies, was applied to the species that swim by body-caudal-fin propulsion at Umax. For pectoral-fin swimmers, Umax increased with fineness, and the rate of increase decreased with fineness, as predicted by the drag model. While the mechanistic and statistical models of the relationship between fineness and Umax were very similar, the mechanistic (and statistical) model explained only a small fraction of the variance in Umax. For body-caudal-fin swimmers, we found a non-linear relationship between fineness and Umax, which was largely negative over most of the range of fineness. This pattern fails to support either predictions from the computational models or standard functional interpretations of body shape variation in fishes. Our results suggest that the widespread hypothesis that a more optimal fineness increases endurance-swimming performance via reduced drag should be limited to fishes that swim with rigid bodies. PMID:24204575
Body fineness ratio as a predictor of maximum prolonged-swimming speed in coral reef fishes.
Walker, Jeffrey A; Alfaro, Michael E; Noble, Mae M; Fulton, Christopher J
2013-01-01
The ability to sustain high swimming speeds is believed to be an important factor affecting resource acquisition in fishes. While we have gained insights into how fin morphology and motion influences swimming performance in coral reef fishes, the role of other traits, such as body shape, remains poorly understood. We explore the ability of two mechanistic models of the causal relationship between body fineness ratio and endurance swimming-performance to predict maximum prolonged-swimming speed (Umax ) among 84 fish species from the Great Barrier Reef, Australia. A drag model, based on semi-empirical data on the drag of rigid, submerged bodies of revolution, was applied to species that employ pectoral-fin propulsion with a rigid body at U max. An alternative model, based on the results of computer simulations of optimal shape in self-propelled undulating bodies, was applied to the species that swim by body-caudal-fin propulsion at Umax . For pectoral-fin swimmers, Umax increased with fineness, and the rate of increase decreased with fineness, as predicted by the drag model. While the mechanistic and statistical models of the relationship between fineness and Umax were very similar, the mechanistic (and statistical) model explained only a small fraction of the variance in Umax . For body-caudal-fin swimmers, we found a non-linear relationship between fineness and Umax , which was largely negative over most of the range of fineness. This pattern fails to support either predictions from the computational models or standard functional interpretations of body shape variation in fishes. Our results suggest that the widespread hypothesis that a more optimal fineness increases endurance-swimming performance via reduced drag should be limited to fishes that swim with rigid bodies.
Extreme Contrast Ratio Imaging of Sirius with a Charge Injection Device
Batcheldor, D; Bahr, C; Jenne, J; Ninkov, Z; Bhaskaran, S; Chapman, T
2015-01-01
The next fundamental steps forward in understanding our place in the universe could be a result of advances in extreme contrast ratio (ECR) imaging and point spread function (PSF) suppression. For example, blinded by quasar light we have yet to fully understand the processes of galaxy formation and evolution, and there is an ongoing race to obtain a direct image of an exoearth lost in the glare of its host star. To fully explore the features of these systems we must perform observations in which contrast ratios of at least one billion can be regularly achieved with sub 0.1" inner working angles. Here we present the details of a latest generation 32-bit charge injection device (CID) that could conceivably achieve contrast ratios on the order of one billion. We also demonstrate some of its ECR imaging abilities for astronomical imaging. At a separation of two arc minutes, we report a direct contrast ratio of Delta(m_v)=18.3, log(CR)=7.3, or 1 part in 20 million, from observations of the Sirius field. The atmosp...
Contrast ratio of veneering and core ceramics as a function of thickness.
Antonson, S A; Anusavice, K J
2001-01-01
The recent development of several dental ceramic products has raised questions concerning the relative translucency potential of these materials. The objective of this study was to test the hypothesis that the contrast ratio of dental core and veneering ceramics is a linear function of ceramic thickness. Four groups of disk-shaped core ceramic specimens and four groups of veneering ceramic specimens (15 mm in diameter and 0.70, 1.10, 1.25, or 1.50 mm in thickness) were prepared for analysis. Five disks were randomly assigned to each of the eight groups. Four core ceramics were selected for study: (1) tetrasilicic fluormica glass ceramic, (2) quadruple-chain silicate glass ceramic, (3) barium silicate glass ceramic, and (4) sintered alumina. The four veneering ceramics included two feldspathic body porcelains, one fine-grained veneering porcelain, and one ultralow-fusing porcelain. There were significant differences among the mean contrast ratio values of these materials. The most translucent group of the core materials was tetrasilicic fluormica glass ceramic, and the least translucent material was sintered alumina. The most translucent group among the veneering ceramics was one of the feldspathic ceramics (Ceramco), and the least translucent material for all thicknesses was the ultralow-fusing veneering ceramic (Duceram LFC). The mean contrast ratio values were significantly different at a thickness of 1.50 mm of the four core ceramic groups and among the four veneering ceramic groups. The results of this study indicate that the tetrasilicic fluormica glass ceramic is generally the most translucent core ceramic for thicknesses of 0.70, 1.10, and 1.25 mm, and Ceramco porcelain is the most translucent veneering ceramic. However, for a thickness of 1.50 mm, the quadruple-chain silicate glass ceramic was the most translucent core ceramic. The relationship between contrast ratio and thickness was linear for all ceramics except Vita VMK 68.
Rannama, Indrek; Port, Kristjan; Bazanov, Boriss
2012-01-01
Maximum gears for youth category riders are limited. As a result, youth category riders are regularly compelled to ride in a high cadence regime. The aim of this study was to investigate if regular work at high cadence regime due to limited transmission in youth category riders reflects in effectual cadence at the point of maximal power generation during the 10 second sprint effort. 24 junior and youth national team cyclist’s average maximal peak power at various cadence regimes was registere...
Danieli, Matteo; Forchhammer, Søren; Andersen, Jakob Dahl
2010-01-01
-likelihood ratios (LLR) in order to combine information sent across different transmissions due to requests. To mitigate the effects of ever-increasing data rates that call for larger HARQ memory, vector quantization (VQ) is investigated as a technique for temporary compression of LLRs on the terminal. A capacity...
D. L. Bricker
1997-01-01
Full Text Available The problem of assigning cell probabilities to maximize a multinomial likelihood with order restrictions on the probabilies and/or restrictions on the local odds ratios is modeled as a posynomial geometric program (GP, a class of nonlinear optimization problems with a well-developed duality theory and collection of algorithms. (Local odds ratios provide a measure of association between categorical random variables. A constrained multinomial MLE example from the literature is solved, and the quality of the solution is compared with that obtained by the iterative method of El Barmi and Dykstra, which is based upon Fenchel duality. Exploiting the proximity of the GP model of MLE problems to linear programming (LP problems, we also describe as an alternative, in the absence of special-purpose GP software, an easily implemented successive LP approximation method for solving this class of MLE problems using one of the readily available LP solvers.
Makeev, Andrey; Ikejimba, Lynda; Lo, Joseph Y.; Glick, Stephen J.
2016-03-01
Although digital mammography has reduced breast cancer mortality by approximately 30%, sensitivity and specificity are still far from perfect. In particular, the performance of mammography is especially limited for women with dense breast tissue. Two out of every three biopsies performed in the U.S. are unnecessary, thereby resulting in increased patient anxiety, pain, and possible complications. One promising tomographic breast imaging method that has recently been approved by the FDA is dedicated breast computed tomography (BCT). However, visualizing lesions with BCT can still be challenging for women with dense breast tissue due to the minimal contrast for lesions surrounded by fibroglandular tissue. In recent years there has been renewed interest in improving lesion conspicuity in x-ray breast imaging by administration of an iodinated contrast agent. Due to the fully 3-D imaging nature of BCT, as well as sub-optimal contrast enhancement while the breast is under compression with mammography and breast tomosynthesis, dedicated BCT of the uncompressed breast is likely to offer the best solution for injected contrast-enhanced x-ray breast imaging. It is well known that use of statistically-based iterative reconstruction in CT results in improved image quality at lower radiation dose. Here we investigate possible improvements in image reconstruction for BCT, by optimizing free regularization parameter in method of maximum likelihood and comparing its performance with clinical cone-beam filtered backprojection (FBP) algorithm.
Lupiani Castellanos, J.; Quinones Rodriguez, L. A.; Richarte Reina, J. M.; Ramos Caballero, L. J.; Angulo Pain, E.; Castro Ramierez, I. J.; Iborra Oquendo, M. A.; Urena Llinares, A.
2011-07-01
The ESTRO Booklet 6 gives the numerical data collected in four different sizes and different accelerators for different beam qualities. Although the end of this guide is the calculation and verification of monitor units, the data we have used Siemens Primus accelerator Mevatron 6 MV photons to perform quality control of the experimental measurements for the tissue-maximum ratio (TMR) and the output factor (OF) in air yen dummy.
ZHANG Xu-ping; YU Yue-qing
2005-01-01
Optimization of structural parameters aimed at improving the load carrying capacity of spatial flexible redundant manipulators is presented in this paper. In order to increase the ratio of load to mass of robots, the cross-sectional parameters and constructional parameters are optimized respectively. The cross-sectional and configurational parameters are optimized simultaneously. The numerical simulation of a 4R spatial manipulator is performed. The results show that the load capacity of robots has been greatly improved through the optimization strategies proposed in this paper.
Optical constants of electrochromic films and contrast ratio of reflective electrochromic devices.
Jaing, Cheng-Chung; Tang, Chien-Jen; Chan, Chih-Chao; Lee, Kun-Hsien; Kuo, Chien-Cheng; Chen, Hsi-Chao; Lee, Cheng-Chung
2014-02-01
This study investigates the optical constants of WO3 electrochromic films and NiO ion-storage films in bleached and colored states and that of a Ta2O5 film used as an ion conductor. These thin films were all prepared by electron-beam evaporation and characterized using a spectroscopic ellipsometer. The spectra obtained using a spectrophotometer and those calculated from the optical constants agreed closely. An all-solid thin-film reflective electrochromic device was fabricated and discussed. Its mean contrast ratio of reflectance in the range of 400-700 nm was 37.91.
High contrast ratio, high uniformity multiple quantum well spatial light modulators
Huang Yuyang; Yang Chen; Yang Hui [Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083 (China); Liu, H C; Cui Guoxin; Bian Lifeng; Zhang Yaohui [Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215125 (China); Wasilewski, Z R; Buchanan, M; Laframboise, S R, E-mail: yhzhang2006@sinano.ac.c [Institute for Microstructural Sciences, National Research Council, Ottawa K1A 0R6 (Canada)
2010-03-15
Our latest research results on GaAs-AlGaAs multiple quantum well spatial light modulators are presented. The thickness uniformity of the epitaxial layers across the 3-inch wafer grown by our molecular beam epitaxy is better than 0.1% and the variation of cavity resonance wavelength within the wafer is only 0.9 nm. A contrast ratio (CR) of 102 by varying bias voltage from 0 to 6.7 V is achieved after fine tuning the cavity by etching an adjust layer. Both theoretical and experimental results demonstrate that incorporating an adjust layer is an effective tuning method for obtaining high CR. (semiconductor integrated circuits)
Physical Layer Authentication Enhancement Using Maximum SNR Ratio Based Cooperative AF Relaying
Jiazi Liu
2017-01-01
Full Text Available Physical layer authentication techniques developed in conventional macrocell wireless networks face challenges when applied in the future fifth-generation (5G wireless communications, due to the deployment of dense small cells in a hierarchical network architecture. In this paper, we propose a novel physical layer authentication scheme by exploiting the advantages of amplify-and-forward (AF cooperative relaying, which can increase the coverage and convergence of the heterogeneous networks. The essence of the proposed scheme is to select the best relay among multiple AF relays for cooperation between legitimate transmitter and intended receiver in the presence of a spoofer. To achieve this goal, two best relay selection schemes are developed by maximizing the signal-to-noise ratio (SNR of the legitimate link to the spoofing link at the destination and relays, respectively. In the sequel, we derive closed-form expressions for the outage probabilities of the effective SNR ratios at the destination. With the help of the best relay, a new test statistic is developed for making an authentication decision, based on normalized channel difference between adjacent end-to-end channel estimates at the destination. The performance of the proposed authentication scheme is compared with that in a direct transmission in terms of outage and spoofing detection.
Sellar, R. Glenn; Deen, Robert G.; Huffman, William C.; Willson, Reginald G.
2016-09-01
Stereophotogrammetry typically employs a pair of cameras, or a single moving camera, to acquire pairs of images from different camera positions, in order to create a three dimensional `range map' of the area being observed. Applications of this technique for building three-dimensional shape models include aerial surveying, remote sensing, machine vision, and robotics. Factors that would be expected to affect the quality of the range maps include the projection function (distortion) of the lenses and the contrast (modulation) and signal-to-noise ratio (SNR) of the acquired image pairs. Basic models of the precision with which the range can be measured assume a pinhole-camera model of the geometry, i.e. that the lenses provide perspective projection with zero distortion. Very-wide-angle or `fisheye' lenses, however (for e.g. those used by robotic vehicles) typically exhibit projection functions that differ significantly from this assumption. To predict the stereophotogrammetric range precision for such applications, we extend the model to the case of an equidistant lens projection function suitable for a very-wide-angle lens. To predict the effects of contrast and SNR on range precision, we perform numerical simulations using stereo image pairs acquired by a stereo camera pair on NASA's Mars rover Curiosity. Contrast is degraded and noise is added to these data in a controlled fashion and the effects on the quality of the resulting range maps are assessed.
Lim, Young Jin; Woo, Chang Woo; Oh, Sang Hoon; Mukherjee, Amrita; Lee, Seung Hee [Department of BIN Fusion Technology and Department of Polymer Nano-Science and Technology, Chonbuk National University, Jeonju, Jeonbuk 561-756 (Korea, Republic of); Baek, Ji Ho; Kim, Kyeong Jin; Yang, Myung Su, E-mail: lsh1@chonbuk.ac.kr [Panel Performance Department, LG Display Co., Ltd., Paju, Gyeonggi-do 413-811 (Korea, Republic of)
2011-08-17
The dark state of homogeneously aligned liquid crystal displays (LCDs) associated with the in-plane switching of a LC director depends on their molecular ordering. We propose a new approach to reduce the light leakage in the dark state of homogeneously aligned LCDs. A very small amount of reactive mesogen (RM) is mixed with the LC material and polymerized at room temperature and also at a low temperature (-20 {sup 0}C) to strengthen the surface-anchoring energy. The contrast ratio of the low-temperature cured cell is improved by about 50% over that of the pure LC cell and the room temperature cured RM-mixed LC cell due to an enhanced order parameter.
Extreme Contrast Ratio Imaging of Sirius with a Charge Injection Device
Batcheldor, D.; Foadi, R.; Bahr, C.; Jenne, J.; Ninkov, Z.; Bhaskaran, S.; Chapman, T.
2016-02-01
The next fundamental steps forward in understanding our place in the universe could be a result of advances in extreme contrast ratio (ECR) imaging and point-spread function (PSF) suppression. For example, blinded by quasar light we have yet to fully understand the processes of galaxy and star formation and evolution, and there is an ongoing race to obtain a direct image of an exo-Earth lost in the glare of its host star. To fully explore the features of these systems, we must perform observations in which contrast ratios (CRs) of at least one billion can be regularly achieved with sub 0.″1 inner working angles. Here, we present the details of a latest-generation 32-bit charge injection device (CID) that could conceivably achieve CRs on the order of one billion. We also demonstrate some of its ECR imaging abilities for astronomical imaging. At a separation of two arcminutes, we report a direct CR of {{Δ }}{m}v=18.3,{log}({CR})=7.3, or 1 part in 20 million, from observations of the Sirius field. The atmospheric conditions present during the collection of this data prevented less modest results, and we expect to be able to achieve higher CRs, with improved inner working angles, simply by operating a CID at a world-class observing site. However, CIDs do not directly provide any PSF suppression. Therefore, combining CID imaging with a simple PSF suppression technique like angular differential imaging could provide a cheap and easy alternative to the complex ECR techniques currently being employed.
Benkhelifa, Fatma
2013-04-01
In this letter, we study the ergodic capacity of a maximum ratio combining (MRC) Rician fading channel with full channel state information (CSI) at the transmitter and at the receiver. We focus on the low Signal-to-Noise Ratio (SNR) regime and we show that the capacity scales as L ΩK+L SNRx log(1SNR), where Ω is the expected channel gain per branch, K is the Rician fading factor, and L is the number of diversity branches. We show that one-bit CSI feedback at the transmitter is enough to achieve this capacity using an on-off power control scheme. Our framework can be seen as a generalization of recently established results regarding the fading-channels capacity characterization in the low-SNR regime. © 2012 IEEE.
Kristensen, Thomas Krogsgaard
2007-01-01
Dette er en afrapportering fra den årlige CONTRAST workshop, der i 2007 blev afholdt i Yaoundé, Cameroon.......Dette er en afrapportering fra den årlige CONTRAST workshop, der i 2007 blev afholdt i Yaoundé, Cameroon....
Matthias Rothe
Full Text Available An increasing number of studies constrain the importance of iron for the long-term retention of phosphorus (P under anoxic conditions, i.e. the formation of reduced iron phosphate minerals such as vivianite (Fe3(PO42⋅8H2O. Much remains unknown about vivianite formation, the factors controlling its occurrence, and its relevance for P burial during early sediment diagenesis. To study the occurrence of vivianite and to assess its relevance for P binding, surface sediments of two hydrologically contrasting waters were analysed by heavy-liquid separation and subsequent powder X-ray diffraction. In Lake Arendsee, vivianite was present in deeper sediment horizons and not in the uppermost layers with a sharp transition between vivianite and non-vivianite bearing layers. In contrast, in lowland river Lower Havel vivianite was present in the upper sediment layers and not in deeper horizons with a gradual transition between non-vivianite and vivianite bearing layers. In both waters, vivianite occurrence was accompanied by the presence of pyrite (FeS2. Vivianite formation was favoured by an elevated iron availability through a lower degree of sulphidisation and was present at a molar ratio of total sulphur to reactive iron smaller than 1.1, only. A longer lasting burden of sediments by organic matter, i.e. due to eutrophication, favours the release of sulphides, and the formation of insoluble iron sulphides leading to a lack of available iron and to less or no vivianite formation. This weakening in sedimentary P retention, representing a negative feedback mechanism (P release in terms of water quality, could be partly compensated by harmless Fe amendments.
S. Gannouni
2016-01-01
Full Text Available In a tunnel fire, the production of smoke and toxic gases remains the principal prejudicial factors to users. The heat is not considered as a major direct danger to users since temperatures up to man level do not reach tenable situations that after a relatively long time except near the fire source. However, the temperatures under ceiling can exceed the thresholds conditions and can thus cause structural collapse of infrastructure. This paper presents a numerical analysis of smoke hazard in tunnel fires with different aspect ratio by large eddy simulation. Results show that the CO concentration increases as the aspect ratio decreases and decreases with the longitudinal ventilation velocity. CFD predicted maximum smoke temperatures are compared to the calculated values using the model of Li et al. and then compared with those given by the empirical equation proposed by kurioka et al. A reasonable good agreement has been obtained. The backlayering length decreases as the ventilation velocity increases and this decrease fell into good exponential decay. The dimensionless interface height and the region of bad visibility increases with the aspect ratio of the tunnel cross-sectional geometry.
Francescon, Paolo; Beddar, Sam; Satariano, Ninfa; Das, Indra J.
2014-01-01
Purpose: Evaluate the ability of different dosimeters to correctly measure the dosimetric parameters percentage depth dose (PDD), tissue-maximum ratio (TMR), and off-axis ratio (OAR) in water for small fields. Methods: Monte Carlo (MC) simulations were used to estimate the variation of kQclin,Qmsrfclin,fmsr for several types of microdetectors as a function of depth and distance from the central axis for PDD, TMR, and OAR measurements. The variation of kQclin,Qmsrfclin,fmsr enables one to evaluate the ability of a detector to reproduce the PDD, TMR, and OAR in water and consequently determine whether it is necessary to apply correction factors. The correctness of the simulations was verified by assessing the ratios between the PDDs and OARs of 5- and 25-mm circular collimators used with a linear accelerator measured with two different types of dosimeters (the PTW 60012 diode and PTW PinPoint 31014 microchamber) and the PDDs and the OARs measured with the Exradin W1 plastic scintillator detector (PSD) and comparing those ratios with the corresponding ratios predicted by the MC simulations. Results: MC simulations reproduced results with acceptable accuracy compared to the experimental results; therefore, MC simulations can be used to successfully predict the behavior of different dosimeters in small fields. The Exradin W1 PSD was the only dosimeter that reproduced the PDDs, TMRs, and OARs in water with high accuracy. With the exception of the EDGE diode, the stereotactic diodes reproduced the PDDs and the TMRs in water with a systematic error of less than 2% at depths of up to 25 cm; however, they produced OAR values that were significantly different from those in water, especially in the tail region (lower than 20% in some cases). The microchambers could be used for PDD measurements for fields greater than those produced using a 10-mm collimator. However, with the detector stem parallel to the beam axis, the microchambers could be used for TMR measurements for all
Kakade, Rohan; Walker, John G.; Phillips, Andrew J.
2016-08-01
Confocal fluorescence microscopy (CFM) is widely used in biological sciences because of its enhanced 3D resolution that allows image sectioning and removal of out-of-focus blur. This is achieved by rejection of the light outside a detection pinhole in a plane confocal with the illuminated object. In this paper, an alternative detection arrangement is examined in which the entire detection/image plane is recorded using an array detector rather than a pinhole detector. Using this recorded data an attempt is then made to recover the object from the whole set of recorded photon array data; in this paper maximum-likelihood estimation has been applied. The recovered object estimates are shown (through computer simulation) to have good resolution, image sectioning and signal-to-noise ratio compared with conventional pinhole CFM images.
Sivaguru, Mayandi; Kabir, Mohammad M.; Gartia, Manas Ranjan; Biggs, David S. C.; Sivaguru, Barghav S.; Sivaguru, Vignesh A.; Berent, Zachary T.; Wagoner Johnson, Amy J.; Fried, Glenn A.; Liu, Gang Logan; Sadayappan, Sakthivel; Toussaint, Kimani C.
2017-02-01
Second-harmonic generation (SHG) microscopy is a label-free imaging technique to study collagenous materials in extracellular matrix environment with high resolution and contrast. However, like many other microscopy techniques, the actual spatial resolution achievable by SHG microscopy is reduced by out-of-focus blur and optical aberrations that degrade particularly the amplitude of the detectable higher spatial frequencies. Being a two-photon scattering process, it is challenging to define a point spread function (PSF) for the SHG imaging modality. As a result, in comparison with other two-photon imaging systems like two-photon fluorescence, it is difficult to apply any PSF-engineering techniques to enhance the experimental spatial resolution closer to the diffraction limit. Here, we present a method to improve the spatial resolution in SHG microscopy using an advanced maximum likelihood estimation (AdvMLE) algorithm to recover the otherwise degraded higher spatial frequencies in an SHG image. Through adaptation and iteration, the AdvMLE algorithm calculates an improved PSF for an SHG image and enhances the spatial resolution by decreasing the full-width-at-halfmaximum (FWHM) by 20%. Similar results are consistently observed for biological tissues with varying SHG sources, such as gold nanoparticles and collagen in porcine feet tendons. By obtaining an experimental transverse spatial resolution of 400 nm, we show that the AdvMLE algorithm brings the practical spatial resolution closer to the theoretical diffraction limit. Our approach is suitable for adaptation in micro-nano CT and MRI imaging, which has the potential to impact diagnosis and treatment of human diseases.
Várnai, Csilla; Burkoff, Nikolas S; Wild, David L
2013-12-10
Maximum Likelihood (ML) optimization schemes are widely used for parameter inference. They maximize the likelihood of some experimentally observed data, with respect to the model parameters iteratively, following the gradient of the logarithm of the likelihood. Here, we employ a ML inference scheme to infer a generalizable, physics-based coarse-grained protein model (which includes Go̅-like biasing terms to stabilize secondary structure elements in room-temperature simulations), using native conformations of a training set of proteins as the observed data. Contrastive divergence, a novel statistical machine learning technique, is used to efficiently approximate the direction of the gradient ascent, which enables the use of a large training set of proteins. Unlike previous work, the generalizability of the protein model allows the folding of peptides and a protein (protein G) which are not part of the training set. We compare the same force field with different van der Waals (vdW) potential forms: a hard cutoff model, and a Lennard-Jones (LJ) potential with vdW parameters inferred or adopted from the CHARMM or AMBER force fields. Simulations of peptides and protein G show that the LJ model with inferred parameters outperforms the hard cutoff potential, which is consistent with previous observations. Simulations using the LJ potential with inferred vdW parameters also outperforms the protein models with adopted vdW parameter values, demonstrating that model parameters generally cannot be used with force fields with different energy functions. The software is available at https://sites.google.com/site/crankite/.
Using the Maximum X-ray Flux Ratio and X-ray Background to Predict Solar Flare Class
Winter, Lisa M
2015-01-01
We present the discovery of a relationship between the maximum ratio of the flare flux (namely, 0.5-4 Ang to the 1-8 Ang flux) and non-flare background (namely, the 1-8 Ang background flux), which clearly separates flares into classes by peak flux level. We established this relationship based on an analysis of the Geostationary Operational Environmental Satellites (GOES) X-ray observations of ~ 50,000 X, M, C, and B flares derived from the NOAA/SWPC flares catalog. Employing a combination of machine learning techniques (K-nearest neighbors and nearest-centroid algorithms) we show a separation of the observed parameters for the different peak flaring energies. This analysis is validated by successfully predicting the flare classes for 100% of the X-class flares, 76% of the M-class flares, 80% of the C-class flares and 81% of the B-class flares for solar cycle 24, based on the training of the parametric extracts for solar flares in cycles 22-23.
Coplen, T.B.; Hopple, J.A.; Böhlke, J.K.; Peiser, H.S.; Rieder, S.E.; Krouse, H.R.; Rosman, K.J.R.; Ding, T.; Vocke, R.D.; Revesz, K.M.; Lamberty, A.; Taylor, P.; De Bievre, P.
2002-01-01
Documented variations in the isotopic compositions of some chemical elements are responsible for expanded uncertainties in the standard atomic weights published by the Commission on Atomic Weights and Isotopic Abundances of the International Union of Pure and Applied Chemistry. This report summarizes reported variations in the isotopic compositions of 20 elements that are due to physical and chemical fractionation processes (not due to radioactive decay) and their effects on the standard atomic weight uncertainties. For 11 of those elements (hydrogen, lithium, boron, carbon, nitrogen, oxygen, silicon, sulfur, chlorine, copper, and selenium), standard atomic weight uncertainties have been assigned values that are substantially larger than analytical uncertainties because of common isotope abundance variations in materials of natural terrestrial origin. For 2 elements (chromium and thallium), recently reported isotope abundance variations potentially are large enough to result in future expansion of their atomic weight uncertainties. For 7 elements (magnesium, calcium, iron, zinc, molybdenum, palladium, and tellurium), documented isotope-abundance variations in materials of natural terrestrial origin are too small to have a significant effect on their standard atomic weight uncertainties. This compilation indicates the extent to which the atomic weight of an element in a given material may differ from the standard atomic weight of the element. For most elements given above, data are graphically illustrated by a diagram in which the materials are specified in the ordinate and the compositional ranges are plotted along the abscissa in scales of (1) atomic weight, (2) mole fraction of a selected isotope, and (3) delta value of a selected isotope ratio. There are no internationally distributed isotopic reference materials for the elements zinc, selenium, molybdenum, palladium, and tellurium. Preparation of such materials will help to make isotope ratio measurements among
Ritter, André; Durst, Jürgen; Gödel, Karl; Haas, Wilhelm; Michel, Thilo; Rieger, Jens; Weber, Thomas; Wucherer, Lukas; Anton, Gisela
2013-01-01
Phase-wrapping artifacts, statistical image noise and the need for a minimum amount of phase steps per projection limit the practicability of x-ray grating based phase-contrast tomography, when using filtered back projection reconstruction. For conventional x-ray computed tomography, the use of statistical iterative reconstruction algorithms has successfully reduced artifacts and statistical issues. In this work, an iterative reconstruction method for grating based phase-contrast tomography is presented. The method avoids the intermediate retrieval of absorption, differential phase and dark field projections. It directly reconstructs tomographic cross sections from phase stepping projections by the use of a forward projecting imaging model and an appropriate likelihood function. The likelihood function is then maximized with an iterative algorithm. The presented method is tested with tomographic data obtained through a wave field simulation of grating based phase-contrast tomography. The reconstruction result...
Karunamuni, R; Maidment, A D A
2014-08-01
Contrast-enhanced (CE) dual-energy (DE) x-ray breast imaging uses a low- and high-energy x-ray spectral pair to eliminate soft-tissue signal variation and thereby increase the detectability of exogenous imaging agents. Currently, CEDE breast imaging is performed with iodinated contrast agents. These compounds are limited by several deficiencies, including rapid clearance and poor tumor targeting ability. The purpose of this work is to identify novel contrast materials whose contrast-to-noise ratio (CNR) is comparable or superior to that of iodine in the mammographic energy range. A monoenergetic DE subtraction framework was developed to calculate the DE signal intensity resulting from the logarithmic subtraction of the low- and high-energy signal intensities. A weighting factor is calculated to remove the dependence of the DE signal on the glandularity of the breast tissue. Using the DE signal intensity and weighting factor, the CNR for materials with atomic numbers (Z) ranging from 1 to 79 are computed for energy pairs between 10 and 50 keV. A group of materials with atomic numbers ranging from 42 to 63 were identified to exhibit the highest levels of CNR in the mammographic energy range. Several of these materials have been formulated as nanoparticles for various applications but none, apart from iodine, have been investigated as CEDE breast imaging agents. Within this group of materials, the necessary dose fraction to the LE image decreases as the atomic number increases. By reducing the dose to the LE image, the DE subtraction technique will not provide an anatomical image of sufficient quality to accompany the contrast information. Therefore, materials with Z from 42 to 52 provide nearly optimal values of CNR with energy pairs and dose fractions that provide good anatomical images. This work is intended to inspire further research into new materials for optimized CEDE breast functional imaging.
Held, Louis F.; Pritchard, Ernest I.
1946-01-01
An investigation was conducted to evaluate the possibilities of utilizing the high-performance characteristics of triptane and xylidines blended with 28-R fuel in order to increase fuel economy by the use of high compression ratios and maximum-economy spark setting. Full-scale single-cylinder knock tests were run with 20 deg B.T.C. and maximum-economy spark settings at compression ratios of 6.9, 8.0, and 10.0, and with two inlet-air temperatures. The fuels tested consisted of triptane, four triptane and one xylidines blend with 28-R, and 28-R fuel alone. Indicated specific fuel consumption at lean mixtures was decreased approximately 17 percent at a compression ratio of 10.0 and maximum-economy spark setting, as compared to that obtained with a compression ratio of 6.9 and normal spark setting. When compression ratio was increased from 6.9 to 10.0 at an inlet-air temperature of 150 F, normal spark setting, and a fuel-air ratio of 0.065, 55-percent triptane was required with 28-R fuel to maintain the knock-limited brake power level obtained with 28-R fuel at a compression ratio of 6.9. Brake specific fuel consumption was decreased 17.5 percent at a compression ratio of 10.0 relative to that obtained at a compression ratio of 6.9. Approximately similar results were noted at an inlet-air temperature of 250 F. For concentrations up through at least 20 percent, triptane can be more efficiently used at normal than at maximum-economy spark setting to maintain a constant knock-limited power output over the range of compression ratios tested.
Belke, Terry W; Pierce, W David
2016-12-01
Rats responded on a multiple variable-ratio (VR) 10 VR 10 schedule of reinforcement in which lever pressing was reinforced by the opportunity to run in a wheel for 30s in both the changed (manipulated) and unchanged components. To generate positive contrast, the schedule of reinforcement in the changed component was shifted to extinction; to generate negative contrast, the schedule was shifted to VR 3. With the shift to extinction in the changed component, wheel-running and local lever-pressing rates increased in the unchanged component, a result supporting positive contrast; however, the shift to a VR 3 schedule in the changed component showed no evidence of negative contrast in the unaltered setting, only wheel running decreased in the unchanged component. Changes in wheel-running rates across components were consistent in showing a compensation effect, depending on whether the schedule manipulation increased or decreased opportunities for wheel running in the changed component. These findings are the first to demonstrate positive behavioral contrast on a multiple schedule with wheel running as reinforcement in both components.
Paul, Jijo, E-mail: jijopaul1980@gmail.com [Department of Diagnostic Radiology, Goethe University Hospital, Theodor-Stern-Kai 7, 60590 Frankfurt am Main (Germany); Department of Biophysics, Goethe University, Max von Laue-Str.1, 60438 Frankfurt am Main (Germany); Bauer, Ralf W. [Department of Diagnostic Radiology, Goethe University Hospital, Theodor-Stern-Kai 7, 60590 Frankfurt am Main (Germany); Maentele, Werner [Department of Biophysics, Goethe University, Max von Laue-Str.1, 60438 Frankfurt am Main (Germany); Vogl, Thomas J. [Department of Diagnostic Radiology, Goethe University Hospital, Theodor-Stern-Kai 7, 60590 Frankfurt am Main (Germany)
2011-11-15
Objective: The purpose of this study was to evaluate image fusion in dual energy computed tomography for detecting various anatomic structures based on the effect on contrast enhancement, contrast-to-noise ratio, signal-to-noise ratio and image quality. Material and methods: Forty patients underwent a CT neck with dual energy mode (DECT under a Somatom Definition flash Dual Source CT scanner (Siemens, Forchheim, Germany)). Tube voltage: 80-kV and Sn140-kV; tube current: 110 and 290 mA s; collimation-2 x 32 x 0.6 mm. Raw data were reconstructed using a soft convolution kernel (D30f). Fused images were calculated using a spectrum of weighting factors (0.0, 0.3, 0.6 0.8 and 1.0) generating different ratios between the 80- and Sn140-kV images (e.g. factor 0.6 corresponds to 60% of their information from the 80-kV image, and 40% from the Sn140-kV image). CT values and SNRs measured in the ascending aorta, thyroid gland, fat, muscle, CSF, spinal cord, bone marrow and brain. In addition, CNR values calculated for aorta, thyroid, muscle and brain. Subjective image quality evaluated using a 5-point grading scale. Results compared using paired t-tests and nonparametric-paired Wilcoxon-Wilcox-test. Results: Statistically significant increases in mean CT values noted in anatomic structures when increasing weighting factors used (all P {<=} 0.001). For example, mean CT values derived from the contrast enhanced aorta were 149.2 {+-} 12.8 Hounsfield Units (HU), 204.8 {+-} 14.4 HU, 267.5 {+-} 18.6 HU, 311.9 {+-} 22.3 HU, 347.3 {+-} 24.7 HU, when the weighting factors 0.0, 0.3, 0.6, 0.8 and 1.0 were used. The highest SNR and CNR values were found in materials when the weighting factor 0.6 used. The difference CNR between the weighting factors 0.6 and 0.3 was statistically significant in the contrast enhanced aorta and thyroid gland (P = 0.012 and P = 0.016, respectively). Visual image assessment for image quality showed the highest score for the data reconstructed using the
Lee, Young Jae [Dept. of Nuclear Medicine, Seoul National University Hospital, Seoul (Korea, Republic of); Lee, Eul Kyu [Dept. of Radiology, Inje Paik University Hospital Jeo-dong, Seoul (Korea, Republic of); Kim, Ki Won [Dept. of Radiology, Kyung Hee University Hospital at Gang-dong, Seoul (Korea, Republic of); Jeong, Hoi Woun [Dept. of Radiological Technology, The Baekseok Culture University, Cheonan (Korea, Republic of); Lyu, Kwang Yeul; Park, Hoon Hee; Son, Jin Hyun; Min, Jung Whan [Dept. of Radiological Technology, The Shingu University, Sungnam (Korea, Republic of)
2017-03-15
The purpose of this study was to measure contrast to noise ratio (CNR) and signal to noise ratio (SNR) according to change of reconstruction from region of interest (ROI) in breast positron emission tomography- computed tomography (PET-CT), and to analyze the CNR and SNR statically. We examined images of breast PET-CT of 100 patients in a University-affiliated hospital, Seoul, Korea. Each patient's image of breast PET-CT were calculated by using Image J. Differences of CNR and SNR among four reconstruction algorithms were tested by SPSS Statistics21 ANOVA test for there was statistical significance (p<0.05). We have analysis socio-demographical variables, CNR and SNR according to reconstruction images, 95% confidence according to CNR and SNR of reconstruction and difference in a mean of CNR and SNR. SNR results, with the quality of distributions in the order of PSF{sub T}OF, Iterative and Iterative-TOF, FBP-TOF. CNR, with the quality of distributions in the order of PSF{sub T}OF, Iterative and Iterative-TOF, FBP-TOF. CNR and SNR of PET-CT reconstruction methods of the breast would be useful to evaluate breast diseases.
Sébastien Ménigot
2013-01-01
Full Text Available Ultrasound contrast imaging has provided more accurate medical diagnoses thanks to the development of innovating modalities like the pulse inversion imaging. However, this latter modality that improves the contrast-to-tissue ratio (CTR is not optimal, since the frequency is manually chosen jointly with the probe. However, an optimal choice of this command is possible, but it requires precise information about the transducer and the medium which can be experimentally difficult to obtain, even inaccessible. It turns out that the optimization can become more complex by taking into account the kind of generators, since the generators of electrical signals in a conventional ultrasound scanner can be unipolar, bipolar, or tripolar. Our aim was to seek the ternary command which maximized the CTR. By combining a genetic algorithm and a closed loop, the system automatically proposed the optimal ternary command. In simulation, the gain compared with the usual ternary signal could reach about 3.9 dB. Another interesting finding was that, in contrast to what is generally accepted, the optimal command was not a fixed-frequency signal but had harmonic components.
Tropical Atlantic SSTS at the Last Glacial Maximum derived from Sr/Ca ratios of fossil coral
Cohen, A. L.; Saenger, C. P.
2006-12-01
The sensitivity of the tropics to climate change is a particularly controversial issue in paleoclimatology. At the heart of this controversy are disagreements amongst different proxy datasets regarding the amplitude of glacial-interglacial changes in temperature, particularly at the sea surface. Data obtained from the aragonitic skeletons of massive reef corals have contributed in no small measure to the debate, yielding LGM and deglacial SSTs 5-6°C cooler than today (Guilderson et al., 1994; McCulloch et al., 1999; Correge et al., 2004), that imply a high sensitivity of Earth's climate to changes in boundary conditions (Crowley, 2000). We used SIMS ion microprobe to analyze Sr/Ca ratios of small pieces of Montastrea coral retrieved from a Barbados drillcore (Guilderson et al., 2001). U/Th dates place the samples between 22 and 24 kyr BP. Localized areas of dissolution and re-growth of secondary (diagenetic) aragonite crystals were identified at centers of septa. Sr/Ca ratios of these crystals were higher than Sr/Ca ratios of original coral crystals preserved in adjacent fasciculi and yielded relatively cooler derived SSTs. The original coral crystals, recognized by their size and orientation, were selectively targeted for analysis using a 20 micron-diameter sample spot. Our calibration study using modern corals from Bermuda, St Croix (USVI) and Barbados indicates that Montastrea Sr/Ca is strongly correlated with SST and with annual extension (growth) rate (Saenger et al., 2006). Growth rate of the fossil corals was determined from measurement of daily growth bands identified in petrographic thin-sections. Application of a growth-dependent Sr/Ca-T calibration yielded Barbados SSTs that were, on average, 2.5°C cooler than today during the LGM and ~1°C cooler than today during Heinrich Event 2. Our LGM SSTs are consistent with the original CLIMAP estimates (CLIMAP, 1976) and with more recent Mg/Ca-based SSTs derived from calcitic foraminifera in the Caribbean
Arbutina B.
2012-01-01
Full Text Available We recalculated the maximum white dwarf mass in ultra-compact X-ray binaries obtained in an earlier paper (Arbutina 2011, by taking the effects of super-Eddington accretion rate on the stability of mass transfer into account. It is found that, although the value formally remains the same (under the assumed approximations, for white dwarf masses M2 >~0.1MCh mass ratios are extremely low, implying that the result for Mmax is likely to have little if any practical relevance.
Bruce T. Milne
2017-05-01
Full Text Available Stream networks are branched structures wherein water and energy move between land and atmosphere, modulated by evapotranspiration and its interaction with the gravitational dissipation of potential energy as runoff. These actions vary among climates characterized by Budyko theory, yet have not been integrated with Horton scaling, the ubiquitous pattern of eco-hydrological variation among Strahler streams that populate river basins. From Budyko theory, we reveal optimum entropy coincident with high biodiversity. Basins on either side of optimum respond in opposite ways to precipitation, which we evaluated for the classic Hubbard Brook experiment in New Hampshire and for the Whitewater River basin in Kansas. We demonstrate that Horton ratios are equivalent to Lagrange multipliers used in the extremum function leading to Shannon information entropy being maximal, subject to constraints. Properties of stream networks vary with constraints and inter-annual variation in water balance that challenge vegetation to match expected resource supply throughout the network. The entropy-Horton framework informs questions of biodiversity, resilience to perturbations in water supply, changes in potential evapotranspiration, and land use changes that move ecosystems away from optimal entropy with concomitant loss of productivity and biodiversity.
M. R. Momayezi
2012-01-01
Full Text Available Rice is an important produced cereal in the world. We evaluated the effect of salt compositions including NaCl and Na2SO4 on suberin lamellae as a major barrier to radial ion and water movements in two rice genotypes representing contrasting salt tolerance levels under salinity stress. Two rice genotypes, Fajr as salt tolerant and Khazar as salt sensitive, were transplanted in sand culture under glasshouse condition. Rice seedlings were treated with five salt compositions including NaCl, Na2SO4, 1 : 1, 1 : 2, and 2 : 1 molar ratios for 40 days. It was proven that suberin lamellae in endodermis of root cell wall were thickened with Na2SO4 treatment. The results demonstrated that the number of passage cells was higher in Fajr genotype than that in Khazar genotype under saline condition. Calcium concentration in root tissue decreased as the SO42- concentration in root media increased. It can be concluded that Fajr genotype is able to keep some passage cells open to maintain Ca2+ uptake. The Ca2+/Na+ ratio in shoot tissue can be also a reliable index for the early recognition of salt stress in these rice genotypes.
Kuhls, Andrew T.; Patel, Vikas; Ionita, Ciprian; Noël, Peter B.; Walczak, Alan M.; Rangwala, Hussain S.; Hoffmann, Kenneth R.; Rudin, Stephen
2006-03-01
A new microangiographic system (MA) integrated into a c-arm gantry has been developed allowing precise placement of a MA at the exact same angle as the standard x-ray image intensifier (II) with unchanged source and object position. The MA can also be arbitrarily moved about the object and easily moved into the field of view (FOV) in front of the lower resolution II when higher resolution angiographic sequences are needed. The benefits of this new system are illustrated in a neurovascular study, where a rabbit is injected with contrast media for varying oblique angles. Digital subtraction angiographic (DSA) images were obtained and compared using both the MA and II detectors for the same projection view. Vessels imaged with the MA appear sharper with smaller vessels visualized. Visualization of ~100 μm vessels was possible with the MA whereas not with the II. Further, the MA could better resolve vessel overlap. Contrast to noise ratios (CNR) were calculated for vessels of varying sizes for the MA versus the II and were found to be similar for large vessels, approximately double for medium vessels, and infinitely better for the smallest vessels. In addition, a 3D reconstruction of selected vessel segments was performed, using multiple (three) projections at oblique angles, for each detector. This new MA/II integrated system should lead to improved diagnosis and image guidance of neurovascular interventions by enabling initial guidance with the low resolution large FOV II combined with use of the high resolution MA during critical parts of diagnostic and interventional procedures.
Saveljev, Vladimir; Kim, Sung-Kyu; Lee, Hyoung; Kim, Hyun-Woo; Lee, Byoungho
2016-02-08
The amplitude of the moiré patterns is estimated in relation to the opening ratio in line gratings and square grids. The theory is developed; the experimental measurements are performed. The minimum and the maximum of the amplitude are found. There is a good agreement between the theoretical and experimental data. This is additionally confirmed by the visual observation. The results can be applied to the image quality improvement in autostereoscopic 3D displays, to the measurements, and to the moiré displays.
Solomon eTesfamariam
2015-10-01
Full Text Available This paper presents a seismic performance evaluation framework using two engineering demand parameters, i.e. maximum and residual inter-story drift ratios, and with consideration of mainshock-aftershock (MSAS earthquake sequences. The evaluation is undertaken within a performance-based earthquake engineering framework in which seismic demand limits are defined with respect to the earthquake return period. A set of 2-, 4-, 8-, and 12-story non-ductile reinforced concrete buildings, located in Victoria, British Colombia, Canada, is considered as a case study. Using 50 mainshock and MSAS earthquake records (two horizontal components per record, incremental dynamic analysis is performed, and the joint probability distribution of maximum and residual inter-story drift ratios is modeled using a novel copula technique. The results are assessed both for collapse and non-collapse limit states. From the results, it can be shown that the collapse assessment of 4- to 12-story buildings is not sensitive to the consideration of MSAS seismic input, whereas for the 2-story building, a 13% difference in the median collapse capacity is caused by the MSAS. For unconditional probability of unsatisfactory seismic performance, which accounts for both collapse and non-collapse limit states, the life safety performance objective is achieved, but it fails to satisfy the collapse prevention performance objective. The results highlight the need for the consideration of seismic retrofitting for the non-ductile reinforced concrete structures.
Han, Xianglu; Price, Paul S
2011-12-01
The maximum cumulative ratio (MCR) developed in previous work is a tool to evaluate the need to perform cumulative risk assessments. MCR is the ratio of the cumulative exposures to multiple chemicals to the maximum exposure from one of the chemicals when exposures are described using a common metric. This tool is used to evaluate mixtures of chemicals measured in samples of untreated ground water as source for drinking water systems in the United States. The mixtures of chemicals in this dataset differ from those examined in our previous work both in terms of the predicted toxicity and compounds measured. Despite these differences, MCR values in this study follow patterns similar to those seen earlier. MCR values for the mixtures have a mean (range) of 2.2 (1.03-5.4) that is much smaller than the mean (range) of 16 (5-34) in the mixtures in previous study. The MCR values of the mixtures decline as Hazard Index (HI) values increase. MCR values for mixtures with larger HI values are not affected by possible contributions from chemicals that may occur at levels below the detection limits. This work provides a second example of use of the MCR tool in the evaluation of mixtures that occur in the environment.
Xianglu Han
2011-12-01
Full Text Available The maximum cumulative ratio (MCR developed in previous work is a tool to evaluate the need to perform cumulative risk assessments. MCR is the ratio of the cumulative exposures to multiple chemicals to the maximum exposure from one of the chemicals when exposures are described using a common metric. This tool is used to evaluate mixtures of chemicals measured in samples of untreated ground water as source for drinking water systems in the United States. The mixtures of chemicals in this dataset differ from those examined in our previous work both in terms of the predicted toxicity and compounds measured. Despite these differences, MCR values in this study follow patterns similar to those seen earlier. MCR values for the mixtures have a mean (range of 2.2 (1.03–5.4 that is much smaller than the mean (range of 16 (5–34 in the mixtures in previous study. The MCR values of the mixtures decline as Hazard Index (HI values increase. MCR values for mixtures with larger HI values are not affected by possible contributions from chemicals that may occur at levels below the detection limits. This work provides a second example of use of the MCR tool in the evaluation of mixtures that occur in the environment.
Terpos, Evangelos; Matsaridis, Dimitris; Koutoulidis, Vassilis; Zagouri, Flora; Christoulas, Dimitrios; Fontara, Sophia; Panourgias, Evangelia; Gavriatopoulou, Maria; Kastritis, Efstathios; Dimopoulos, Meletios A; Moulopoulos, Lia A
2017-08-01
The aim of the study was to assess the value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in patients with newly diagnosed multiple myeloma (MM) who were treated with novel anti-myeloma agents. We studied 60 previously untreated MM patients at diagnosis, 14 with smoldering MM (SMM) and 5 with MGUS. All patients underwent MRI of the thoracolumbar spine and pelvis before the administration of any kind of therapy, and DCE-MRI was performed. The MRI perfusion parameters evaluated were wash-in (WIN), washout (WOUT), time-to-peak (TTPK), time-to-maximum slope (TMSP), and the WIN/TMSP ratio. The following serum levels of angiogenic cytokines were measured on the day of MRI: VEGF, angiogenin (Ang), angiopoietin-1 (Angp-1), and -2 (Angp-2). Symptomatic MM patients had increased WIN compared to SMM (p ISS. Patients with R-ISS-3 had lower TTPK median value (23 s, range 18-29 s) compared to patients with R-ISS-2 (48 s, range 27-68 s) and patients with R-ISS-1 MM (54 s, range 42-76 s; p ANOVA = 0.01). A subset of patients with low TTPK (lower quartile) had shorter time to progression compared to all other patients. These data suggest that certain DCE-MRI parameters correlate with R-ISS and adverse prognostic features of angiogenesis, such as the ratio of Angp-1/Angp-2.
Kousi, Evanthia; Borri, Marco; Dean, Jamie; Panek, Rafal; Scurr, Erica; Leach, Martin O.; Schmidt, Maria A.
2016-01-01
MRI has been extensively used in breast cancer staging, management and high risk screening. Detection sensitivity is paramount in breast screening, but variations of signal-to-noise ratio (SNR) as a function of position are often overlooked. We propose and demonstrate practical methods to assess spatial SNR variations in dynamic contrast-enhanced (DCE) breast examinations and apply those methods to different protocols and systems. Four different protocols in three different MRI systems (1.5 and 3.0 T) with receiver coils of different design were employed on oil-filled test objects with and without uniformity filters. Twenty 3D datasets were acquired with each protocol; each dataset was acquired in under 60 s, thus complying with current breast DCE guidelines. In addition to the standard SNR calculated on a pixel-by-pixel basis, we propose other regional indices considering the mean and standard deviation of the signal over a small sub-region centred on each pixel. These regional indices include effects of the spatial variation of coil sensitivity and other structured artefacts. The proposed regional SNR indices demonstrate spatial variations in SNR as well as the presence of artefacts and sensitivity variations, which are otherwise difficult to quantify and might be overlooked in a clinical setting. Spatial variations in SNR depend on protocol choice and hardware characteristics. The use of uniformity filters was shown to lead to a rise of SNR values, altering the noise distribution. Correlation between noise in adjacent pixels was associated with data truncation along the phase encoding direction. Methods to characterise spatial SNR variations using regional information were demonstrated, with implications for quality assurance in breast screening and multi-centre trials.
Schwab, Felix [Ludwig Maximilians-Univ. Hospital Munich (Germany). Inst. for Clinical Radiology; Schleede, Simone; Hahn, Dieter [Technische Univ. Muenchen, Garching (Germany). Dept. of Physics and Inst. of Medical Engineering] [and others
2013-10-01
Purpose: An experimental comparison of the contrast-to-noise ratio (CNR) between transmission and dark-field signals in grating-based X-ray imaging for ex-vivo murine lung tissue. Materials and Methods: Lungs from three healthy mice were imaged ex vivo using a laser-driven compact synchrotron X-ray source. Background noise of transmission and dark-field signal was quantified by measuring the standard deviation in a region of interest (ROI) placed in a homogeneous area outside the specimen. Image contrast was quantified by measuring the signal range in rectangular ROIs placed in central and peripheral lung parenchyma. The relative contrast gain (RCG) of dark-field over transmission images was calculated as CNRDF / CNRT. Results: In all images, there was a trend for contrast-to-noise ratios of dark-field images (CNRDF) to be higher than for transmission images (CNRT) for all ROIs (median 61 vs. 38, p = 0.10), but the difference was statistically significant only for peripheral ROIs (61 vs. 32, p = 0.03). Median RCG was >1 for all ROIs (1.84). RCG values were significantly smaller for central ROIs than for peripheral ROIs (1.34 vs. 2.43, p = 0.03). Conclusion: The contrast-to-noise ratio of dark-field images compares more favorably to the contrast-to-noise ratio of transmission images for peripheral lung regions as compared to central regions. For any specific specimen, a calculation of the RCG allows comparing which X-ray modality (dark-field or transmission imaging) produces better contrast-to-noise characteristics in a well-defined ROI. (orig.)
Sandborg, Michael; Carlsson, G.A. (Linkoeping Univ. (Sweden). Dept. of Radiation Physics)
1992-06-01
A lower limit to patient irradiation in diagnostic radiology is set by the fundamental stochastics of the energy imparted to the image receptor (quantum noise). Image quality is investigated here and expressed in terms of the signal-to-noise ratio due to quantum noise. The Monte Carlo method is used to calculate signal-to-noise ratios (SNR{sub {Delta}S}) and detective quantum efficiencies (DQE{sub {Delta}S}) in imaging thin contrasting details of air, fat, bone and iodine within a water phantom using x-ray spectra (40-140 kV) and detectors of CsI, BaFCl and Gd{sub 2}O{sub 2}S. The atomic composition of the contrasting detail influences considerably the values of SNR{sub {Delta}S} due to the different modulations of the energy spectra of primary photons passing beside and through the contrasting detail. (author).
Measuring CO2 fluxes from contrasting soil management practices is important for understanding the role of agriculture in source-sink relationship with CO2 flux. There are several micrometeorological methods for measuring CO2 emissions, however all are expensive and thus do not easily lend themselve...
Jirasek, A [Department of Physics and Astronomy, University of Victoria, Victoria BC V8W 3P6 (Canada); Matthews, Q [Department of Physics and Astronomy, University of Victoria, Victoria BC V8W 3P6 (Canada); Hilts, M [Medical Physics, BC Cancer Agency-Vancouver Island Centre, Victoria BC V8R 6V5 (Canada); Schulze, G [Michael Smith Laboratories, University of British Columbia, Vancouver BC V6T 1Z4 (Canada); Blades, M W [Department of Chemistry, University of British Columbia, Vancouver BC V6T 1Z1 (Canada); Turner, R F B [Michael Smith Laboratories, University of British Columbia, Vancouver BC V6T 1Z4 (Canada); Department of Chemistry, University of British Columbia, Vancouver BC V6T 1Z1 (Canada); Department of Electrical and Computer Engineering, University of British Columbia, Vancouver BC V6T 1Z4 (Canada)
2006-05-21
This study presents a new method of image signal-to-noise ratio (SNR) enhancement by utilizing a newly developed 2D two-point maximum entropy regularization method (TPMEM). When utilized as an image filter, it is shown that 2D TPMEM offers unsurpassed flexibility in its ability to balance the complementary requirements of image smoothness and fidelity. The technique is evaluated for use in the enhancement of x-ray computed tomography (CT) images of irradiated polymer gels used in radiation dosimetry. We utilize a range of statistical parameters (e.g. root-mean square error, correlation coefficient, error histograms, Fourier data) to characterize the performance of TPMEM applied to a series of synthetic images of varying initial SNR. These images are designed to mimic a range of dose intensity patterns that would occur in x-ray CT polymer gel radiation dosimetry. Analysis is extended to a CT image of a polymer gel dosimeter irradiated with a stereotactic radiation therapy dose distribution. Results indicate that TPMEM performs strikingly well on radiation dosimetry data, significantly enhancing the SNR of noise-corrupted images (SNR enhancement factors >15 are possible) while minimally distorting the original image detail (as shown by the error histograms and Fourier data). It is also noted that application of this new TPMEM filter is not restricted exclusively to x-ray CT polymer gel dosimetry image data but can in future be extended to a wide range of radiation dosimetry data.
Jirasek, A; Matthews, Q; Hilts, M; Schulze, G; Blades, M W; Turner, R F B
2006-05-21
This study presents a new method of image signal-to-noise ratio (SNR) enhancement by utilizing a newly developed 2D two-point maximum entropy regularization method (TPMEM). When utilized as an image filter, it is shown that 2D TPMEM offers unsurpassed flexibility in its ability to balance the complementary requirements of image smoothness and fidelity. The technique is evaluated for use in the enhancement of x-ray computed tomography (CT) images of irradiated polymer gels used in radiation dosimetry. We utilize a range of statistical parameters (e.g. root-mean square error, correlation coefficient, error histograms, Fourier data) to characterize the performance of TPMEM applied to a series of synthetic images of varying initial SNR. These images are designed to mimic a range of dose intensity patterns that would occur in x-ray CT polymer gel radiation dosimetry. Analysis is extended to a CT image of a polymer gel dosimeter irradiated with a stereotactic radiation therapy dose distribution. Results indicate that TPMEM performs strikingly well on radiation dosimetry data, significantly enhancing the SNR of noise-corrupted images (SNR enhancement factors >15 are possible) while minimally distorting the original image detail (as shown by the error histograms and Fourier data). It is also noted that application of this new TPMEM filter is not restricted exclusively to x-ray CT polymer gel dosimetry image data but can in future be extended to a wide range of radiation dosimetry data.
Nakata, Manabu; Okada, Takashi; Komai, Yoshinori; Nohara, Hiroki [Kyoto Univ. (Japan). Hospital
1996-08-01
Modern linear accelerators have four independent jaws and multileaf collimators (MLC) of 1 cm width at the isocenter. Asymmetric fields defined by such independent jaws and irregular multileaf collimated fields can be used to match adjacent fields or to spare the spinal cord in external photon beam radiotherapy. We have developed a new approximate algorithm for depth dose calculations at the collimator rotation axis. The program is based on Clarkson`s principle, and uses a more accurate modification of Day`s method for asymmetric fields. Using this method, tissue-maximum ratios (TMR) and field factors of ten kinds of asymmetric fields and ten different irregular multileaf collimated fields were calculated and compared with the measured data for 6 MV and 15 MV photon beams. The dose accuracy with the general A/Pe method was about 3%, however, with the new modified Day`s method, accuracy was within 1.7% for TMR and 1.2% for field factors. The calculated TMR and field factors were found to be in good agreement with measurements for both the 6 MV and 15 MV photon beams. (author)
Vallotton, Nathalie; Price, Paul S
2016-05-17
This paper uses the maximum cumulative ratio (MCR) as part of a tiered approach to evaluate and prioritize the risk of acute ecological effects from combined exposures to the plant protection products (PPPs) measured in 3 099 surface water samples taken from across the United States. Assessments of the reported mixtures performed on a substance-by-substance approach and using a Tier One cumulative assessment based on the lowest acute ecotoxicity benchmark gave the same findings for 92.3% of the mixtures. These mixtures either did not indicate a potential risk for acute effects or included one or more individual PPPs that had concentrations in excess of their benchmarks. A Tier Two assessment using a trophic level approach was applied to evaluate the remaining 7.7% of the mixtures. This assessment reduced the number of mixtures of concern by eliminating the combination of endpoint from multiple trophic levels, identified invertebrates and nonvascular plants as the most susceptible nontarget organisms, and indicated that a only a very limited number of PPPs drove the potential concerns. The combination of the measures of cumulative risk and the MCR enabled the identification of a small subset of mixtures where a potential risk would be missed in substance-by-substance assessments.
Starkel, W. A.; Wolff, J.; Eckberg, A.; Ramos, F.
2008-12-01
Many early Columbia River Basalt flows of the Steens and Imnaha Formations are characterized by abundant, texturally complex, coarse plagioclase phenocrysts. In Imnaha lavas, the feldspars typically have more radiogenic 87Sr/86Sr than whole rock and matrix, and may exhibit complex isotopic zoning that is not correlated with An content. Imnaha plagioclase grains are interpreted as variably-contaminated crystals produced when high-crystallinity mid-crustal basaltic intrusions exchanged interstitial melt with adjacent partly-melted crustal rock; this isotopically variable debris was then remobilized by subsequent intrusion of mantle-derived basalt and brought to the surface as an isotopically heterogeneous mixture. In contrast, plagioclase grains in the texturally very similar Steens lavas are isotopically near-homogeneous and 87Sr/86Sr is not significantly displaced from that of the bulk rock. This is consistent with magma- crust interaction at low degrees of crustal melting during the early stages of the Columbia River flood basalt episode, where Steens and Imnaha lavas were erupted from distinct magma systems hosted by different types of crust that exerted different degrees of isotopic leverage on the mantle-derived magmas [1]. Thermal input to the Steens system declined at the same time as the Imnaha magmatic flux increased to ultimately produce the huge outpouring of Grande Ronde lavas, which are mixtures of mantle- and crust-derived liquids, the latter produced during high degrees of crustal melting during the time of peak magmatic flux. [1] Wolff et al. (2008) Nature Geoscience 1, 177-180.
Rohani, S A; Ghomashchi, S; Umoh, J; Holdsworth, D W; Agrawal, S K; Ladak, H M
2016-12-01
High-resolution imaging of middle-ear geometry is necessary for finite-element modeling. Although micro-computed tomography (microCT) is widely used because of its ability to image bony structures of the middle ear, it is difficult to visualize soft tissues - including the tympanic membrane and the suspensory ligaments/tendons - because of lack of contrast. The objective of this research is to quantitatively evaluate the efficacy of iodine potassium iodide (IKI) solution as a contrast agent. Six human temporal bones were used in this experiment, which were obtained in right-left pairs, from three cadaveric heads. All bones were fixed using formaldehyde. Three bones (one from each pair) were stained in IKI solution for 2 days, whereas the other three were not stained. Samples were scanned using a microCT system at a resolution of 20 μm. Eight soft tissues in the middle ear were segmented: anterior mallear ligament, incudomallear joint, lateral mallear ligament, posterior incudal ligament, stapedial annular ligament, stapedius muscle, tympanic membrane and tensor tympani muscle. Contrast-to-noise ratios (CNRs) of each soft tissue were calculated for each temporal bone. Combined CNRs of the soft tissues in unstained samples were 6.1 ± 3.0, whereas they were 8.1 ± 2.7 in stained samples. Results from Welch's t-test indicate significant difference between the two groups at a 95% confidence interval. Results for paired t-tests for each of the individual soft tissues also indicated significant improvement of contrast in all tissues after staining. Relatively large soft tissues in the middle ear such as the tympanic membrane and the tensor tympani muscle were impacted by staining more than smaller tissues such as the stapedial annular ligament. The increase in contrast with IKI solution confirms its potential application in automatic segmentation of the middle-ear soft tissues.
LIU Qian; YE Jing-ming; XU Ling; DUAN Xue-ning; ZHAO Jian-xin; LIU Yin-hua
2012-01-01
Background Earlier studies have examined the association between the diameter of primary tumors measured by magnetic resonance imaging (MRI) and histopathology in breast cancer patients.However,the diameter does not completely describe the dimensions of the breast tumor or its volumetric proportion relative to the whole breast.The association between breast tumor volume/breast volume ratios measured by these two techniques has not been reported.Methods Seventy-three patients were recruited from female patients with primary breast tumors admitted to our center between January and December 2010.They were divided into two groups.Group A (n=46) underwent modified radical mastectomy (MRM),and Group B (n=27) underwent preoperative neoadjuvant chemotherapy before MRM.They were examined by dynamic-contrast enhanced MRI (DCE-MRI) to measure breast volumes (BVs),tumor volumes (TVs),and tumor volume/breast volume ratios (TV/BV).These measurements were compared with histopathology results after MRM,and the associations between MRI and pathology were analyzed by linear regression and Bland-Altman analysis.Results For Group A,the correlation coefficients for BVs,TVs,and TV/BV ratios measured by the two techniques were 0.938,0.921,and 0.897 (all P ＜0.001),respectively.For Group B,the correlation coefficients for BVs,TVs,and TV/BV ratios were 0.936,0.902,and 0.869 (all P＜0.01),respectively.The results suggest statistically significant correlations between these parameters measured by the two techniques for both groups.Conclusion For these patients,BVs,TVs,and TV/BV ratios measured by DCE-MRI significantly correlated with those determined by histopathology.
Seco, R.; Peñuelas, J.; Filella, I.; Llusià, J.; Molowny-Horas, R.; Schallhart, S.; Metzger, A.; Müller, M.; Hansel, A.
2011-12-01
Atmospheric volatile organic compounds (VOCs) are involved in ozone and aerosol generation, thus having implications for air quality and climate. VOCs and their emissions by vegetation also have important ecological roles as they can protect plants from stresses and act as communication cues between plants and between plants and animals. In spite of these key environmental and biological roles, the reports on seasonal and daily VOC mixing ratios in the literature for Mediterranean natural environments are scarce. We conducted seasonal (winter and summer) measurements of VOC mixing ratios in an elevated (720 m a.s.l.) holm oak Mediterranean forest site near the metropolitan area of Barcelona (NE Iberian Peninsula). Methanol was the most abundant compound among all the VOCs measured in both seasons. While aromatic VOCs showed almost no seasonal variability, short-chain oxygenated VOCs presented higher mixing ratios in summer, presumably due to greater emission by vegetation and increased photochemistry, both enhanced by the high temperatures and solar radiation in summer. Isoprenoid VOCs showed the biggest seasonal change in mixing ratios: they increased by one order of magnitude in summer, as a result of the vegetation's greater physiological activity and emission rates. The maximum diurnal concentrations of ozone increased in summer too, most likely due to more intense photochemical activity and the higher levels of VOCs in the air. The daily variation of VOC mixing ratios was mainly governed by the wind regime of the mountain, as the majority of the VOC species analyzed followed a very similar diel cycle. Mountain and sea breezes that develop after sunrise advect polluted air masses to the mountain. These polluted air masses had previously passed over the urban and industrial areas surrounding the Barcelona metropolitan area, where they were enriched in NOx and in VOCs of biotic and abiotic origin. Moreover, these polluted air masses receive additional biogenic
R. Seco
2011-12-01
Full Text Available Atmospheric volatile organic compounds (VOCs are involved in ozone and aerosol generation, thus having implications for air quality and climate. VOCs and their emissions by vegetation also have important ecological roles as they can protect plants from stresses and act as communication cues between plants and between plants and animals. In spite of these key environmental and biological roles, the reports on seasonal and daily VOC mixing ratios in the literature for Mediterranean natural environments are scarce.
We conducted seasonal (winter and summer measurements of VOC mixing ratios in an elevated (720 m a.s.l. holm oak Mediterranean forest site near the metropolitan area of Barcelona (NE Iberian Peninsula. Methanol was the most abundant compound among all the VOCs measured in both seasons. While aromatic VOCs showed almost no seasonal variability, short-chain oxygenated VOCs presented higher mixing ratios in summer, presumably due to greater emission by vegetation and increased photochemistry, both enhanced by the high temperatures and solar radiation in summer. Isoprenoid VOCs showed the biggest seasonal change in mixing ratios: they increased by one order of magnitude in summer, as a result of the vegetation's greater physiological activity and emission rates. The maximum diurnal concentrations of ozone increased in summer too, most likely due to more intense photochemical activity and the higher levels of VOCs in the air.
The daily variation of VOC mixing ratios was mainly governed by the wind regime of the mountain, as the majority of the VOC species analyzed followed a very similar diel cycle. Mountain and sea breezes that develop after sunrise advect polluted air masses to the mountain. These polluted air masses had previously passed over the urban and industrial areas surrounding the Barcelona metropolitan area, where they were enriched in NO_{x} and in VOCs of biotic and abiotic origin. Moreover, these
Cianfrini, C.; Corcione, M.; Habib, E.; Quintino, A.
2017-06-01
Natural convection in air-filled rectangular cavities inclined with respect to gravity, so that the heated wall is facing upwards, is studied numerically under the assumption of two-dimensional laminar flow. A computational code based on the SIMPLE-C algorithm is used for the solution of the system of the mass, momentum and energy transfer governing equations. Simulations are performed for height-to-width aspect ratios of the enclosure from 0.25 to 8, Rayleigh numbers based on the length of the heated and cooled walls from 102 to 107, and tilting angles of the enclosure from 0° to 75°. The existence of an optimal tilting angle is confirmed for any investigated configuration, at a location that increases as the Rayleigh number is decreased, and the height-to-width aspect ratio of the cavity are increased, unless the value of the Rayleigh number is that corresponding to the onset of convection or just higher. Dimensionless correlating equations are developed to predict the optimal tilting angle and the heat transfer performance of the enclosure.
结合最大方差比准则和PCNN模型的图像分割%Image segmentation with PCNN model and maximum of variance ratio
辛国江; 邹北骥; 李建锋; 陈再良; 蔡美玲
2011-01-01
脉冲耦合神经网络(PCNN)模型在图像分割方面有着很好的应用.在各项参数确定的情况下,其分割结果的好坏取决于循环迭代次数的多少,而PCNN模型自身无法实现迭代次数的自动判定.为此提出一种结合最大方差比准则的PCNN迭代次数自动判定算法,用于实现图像的自动分割.算法利用最大方差比准则找到图像的最优分割界限,确定PCNN的迭代次数,获得最优图像分割结果,然后利用最大香农熵准则验证分割结果.实验表明:提出的算法实现了PCNN迭代次数的自动判定,提高了PCNN的迭代速度,运行效率优于基于2D-OTSU和基于交叉熵的自动分割算法,图像分割效果良好.%The Pulse Coupled Neural Network (FCNN) model is very suitable for image segmentation. With given parameters, the results of segmentation are determined only by the times of iteration. However, the PCNN model itself cannot automatically discover the optimal iteration times. Therefore, an algorithm based on the maximization of variance ratio criteria is proposed to solve this problem. The algorithm can automatically discover the best iteration times by applying the maximization of variance ratio criteria, and get the best segmentation results. Eventually, the Shannon entropy rule is used to check the segmentation results. The experimental results show that the algorithm can automatically discover the optimal iteration times, the segmentation results are satisfactory, and it improves the speed of PCNN iteration, and it is also more efficient than the automatic segmentation algorithm based 2D-OTSU and cross-entropy.
Kuhls, Andrew T; Patel, Vikas; Ionita, Ciprian; Noël, Peter B; Walczak, Alan M; Rangwala, Hussain S; Hoffmann, Kenneth R; Rudin, Stephen
2006-01-01
A new microangiographic system (MA) integrated into a c-arm gantry has been developed allowing precise placement of a MA at the exact same angle as the standard x-ray image intensifier (II) with unchanged source and object position. The MA can also be arbitrarily moved about the object and easily moved into the field of view (FOV) in front of the lower resolution II when higher resolution angiographic sequences are needed. The benefits of this new system are illustrated in a neurovascular study, where a rabbit is injected with contrast media for varying oblique angles. Digital subtraction angiographic (DSA) images were obtained and compared using both the MA and II detectors for the same projection view. Vessels imaged with the MA appear sharper with smaller vessels visualized. Visualization of ~100 μm vessels was possible with the MA whereas not with the II. Further, the MA could better resolve vessel overlap. Contrast to noise ratios (CNR) were calculated for vessels of varying sizes for the MA versus the II and were found to be similar for large vessels, approximately double for medium vessels, and infinitely better for the smallest vessels. In addition, a 3D reconstruction of selected vessel segments was performed, using multiple (three) projections at oblique angles, for each detector. This new MA/II integrated system should lead to improved diagnosis and image guidance of neurovascular interventions by enabling initial guidance with the low resolution large FOV II combined with use of the high resolution MA during critical parts of diagnostic and interventional procedures.
Lionello, Piero; Conte, Dario; Marzo, Luigi; Scarascia, Luca
2017-04-01
The maximum level that water reaches during a storm along the coast has important consequences on coastal defences and coastal erosion. It depends on future sea level, storm surges, ocean wind generated waves, vertical land motion. The future sea level in turn depends on water mass addition and steric contributions (with a thermosteric and halosteric component). This study proposes a practical methodology for assessing the effects of these different factors (which need to be estimated at sub-regional scale) and applies it to a 7-member model ensemble of regional climate model simulations (developed and carried out in the CIRCE fp6 project) covering the period 1951-2050 under the A1B emission scenario. Sea level pressure and wind fields are used for forcing a hydro-dynamical shallow water model (HYPSE), wind fields are used for forcing a wave model (WAM), obtaining estimates of storm surges and ocean waves, respectively. Thermosteric and halosteric effects are diagnosed from the projections of sea temperature and salinity. Steric expansion and storminess are shown to be contrasting factors: in the next decades wave and storm surge maxima will decrease while thermosteric expansion will increase mean sea level. These two effects will to a large extent compensate each other, so that their superposition will increase/decrease the maximum water level along two comparable fractions of the coastline (about 15-20%) by the mid 21st century. However, mass addition across the Gibraltar Strait to the Mediterranean Sea will likely become the dominant factor and determine an increase of the maximum water level along most of the coastline.
Demirturk Kocasarac, Husniye; Helvacioglu Yigit, Dilek; Bechara, Boulos; Sinanoglu, Alper; Noujeim, Marcel
2016-01-01
To compare the contrast-to-noise ratio (CNR) of multiple acquisition settings for four types of retrograde filling materials in CBCT images taken for endodontic surgery follow-up. 20 maxillary central incisors were endodontically treated and obturated with 4 different root-end filling materials: amalgam, mineral trioxide aggregate, SuperEBA(™) (Harry J Bosworth Company, Skokie, IL) and Biodentine™ (Septodont, Saint-Maur-des-Faussés, France). Teeth were placed in a skull and scanned, one by one, with the Planmeca ProMax(®) 3D Max (Planmeca, Helsinki, Finland); at different voltages: 66, 76, 84 and 96 kVp; with low, normal and high resolution and high definition (HD); with and without metal artefact reduction (MAR). Images were analyzed using ImageJ software (National Institutes of Health, Bethesda, MD) to calculate the CNR. The dose-area product was registered, and the effective dose calculated. No statistically significant difference was noted between the four materials. 84 and 96 kVp with low resolution and the use of MAR-generated images that have statistically better CNR than 66 and 76 kVp with HD, normal and high resolutions and without MAR. The use of low resolution also generated the smallest value of effective dose. The best setting for radiographic follow-up in an endodontic surgery with retrograde filling on the Planmeca ProMax is 96 kVp with low resolution and high MAR; this setting produced one of the lowest effective doses.
Kinkhabwala, Ali
2013-01-01
The most fundamental problem in statistics is the inference of an unknown probability distribution from a finite number of samples. For a specific observed data set, answers to the following questions would be desirable: (1) Estimation: Which candidate distribution provides the best fit to the observed data?, (2) Goodness-of-fit: How concordant is this distribution with the observed data?, and (3) Uncertainty: How concordant are other candidate distributions with the observed data? A simple unified approach for univariate data that addresses these traditionally distinct statistical notions is presented called "maximum fidelity". Maximum fidelity is a strict frequentist approach that is fundamentally based on model concordance with the observed data. The fidelity statistic is a general information measure based on the coordinate-independent cumulative distribution and critical yet previously neglected symmetry considerations. An approximation for the null distribution of the fidelity allows its direct conversi...
Yuan-Hong Jiang
Full Text Available OBJECTIVES: The aim of this study was to investigate the predictive values of the total International Prostate Symptom Score (IPSS-T and voiding to storage subscore ratio (IPSS-V/S in association with total prostate volume (TPV and maximum urinary flow rate (Qmax in the diagnosis of bladder outlet-related lower urinary tract dysfunction (LUTD in men with lower urinary tract symptoms (LUTS. METHODS: A total of 298 men with LUTS were enrolled. Video-urodynamic studies were used to determine the causes of LUTS. Differences in IPSS-T, IPSS-V/S ratio, TPV and Qmax between patients with bladder outlet-related LUTD and bladder-related LUTD were analyzed. The positive and negative predictive values (PPV and NPV for bladder outlet-related LUTD were calculated using these parameters. RESULTS: Of the 298 men, bladder outlet-related LUTD was diagnosed in 167 (56%. We found that IPSS-V/S ratio was significantly higher among those patients with bladder outlet-related LUTD than patients with bladder-related LUTD (2.28±2.25 vs. 0.90±0.88, p1 or >2 was factored into the equation instead of IPSS-T, PPV were 91.4% and 97.3%, respectively, and NPV were 54.8% and 49.8%, respectively. CONCLUSIONS: Combination of IPSS-T with TPV and Qmax increases the PPV of bladder outlet-related LUTD. Furthermore, including IPSS-V/S>1 or >2 into the equation results in a higher PPV than IPSS-T. IPSS-V/S>1 is a stronger predictor of bladder outlet-related LUTD than IPSS-T.
Fourmaux, S; Serbanescu, C; Kincaid, R E; Krol, A; Kieffer, J C
2008-12-12
We report K(alpha) x-ray production with a high energy (110 mJ per pulse at 800 nm before compression/15 mJ at 400 nm after compression), high repetition rate (100 Hz), and high pulse contrast (better than 10(-9) at 400 nm) laser system. To develop laser-based x-ray sources for biomedical imaging requires to use high-energy and high-power ultra-fast laser system where compression is achieved under vacuum. Using this type of laser system, we demonstrate long-term stability of the x-ray yield, conversion efficiency higher than 1.5 x 10(-5) with a Mo target, and the x-ray spot size close to the optical focal spot. This high-repetition K(alpha) x-ray source can be very useful for x-ray phase-contrast imaging.
李娟; 张克兆; 李生权; 刘超
2015-01-01
Considering the permanent magnet synchronous wind generator system with uncertainties, multi interferences and low efficiency, a maximum power point tracking with active disturbance rejection control strategy based on the best tip speed ratio was proposed to track the motor speed real time and to capture the maximum power. The active disturbance rejection controller does not depend on the mathematical model of the system. The uncertainties including nonlinear, strong coupling, parameter variations and ex-ternal disturbances wer lumped to the total disturbances of system, which affect the tracking speed in real time. The extended state observer estimates the total disturbances, and then compensates them through the feedback controller, which improves the speed tracking ability. Simulation results show that, com-pared with the traditional PI control method, the proposed control strategy not only guarantees the system to achieve maximum power output, but also has strong robustness against uncertain dynamics and external disturbances.%针对永磁同步风力发电系统中存在的不确定、多干扰、效率低等问题,提出一种以实现最大功率跟踪控制为目标,实时跟踪电机转速的基于最佳叶尖速比的自抗扰控制策略. 该方法不依赖于系统数学模型,将永磁同步风力发电机存在的、影响转速难以实时跟踪的非线性、强耦合、参数变化、外界干扰等不确定性看成系统总干扰. 通过扩张状态观测器对系统的总干扰进行估计,然后通过反馈控制器进行干扰补偿,从而提高转速的跟踪能力. 仿真结果表明,与传统的PI控制方法相比,自抗扰控制不仅能保证系统实现最大功率输出,而且提高了系统的鲁棒性和抗干扰性能.
Bae, Yun Jung; Choi, Byung Se; Yoon, Yeon Hong; Woo, Leonard Sun; Jung, Cheol Kyu; Kim, Jae Hyoung [Dept. of Radiology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam (Korea, Republic of); Lee, Kyung Mi [Dept. of Radiology, Kyung Hee University College of Medicine, Kyung Hee University Hospital, Seoul (Korea, Republic of)
2017-08-01
To evaluate the diagnostic benefits of 5-mm maximum intensity projection of improved motion-sensitized driven-equilibrium prepared contrast-enhanced 3D T1-weighted turbo-spin echo imaging (MIP iMSDE-TSE) in the detection of brain metastases. The imaging technique was compared with 1-mm images of iMSDE-TSE (non-MIP iMSDE-TSE), 1-mm contrast-enhanced 3D T1-weighted gradient-echo imaging (non-MIP 3D-GRE), and 5-mm MIP 3D-GRE. From October 2014 to July 2015, 30 patients with 460 enhancing brain metastases (size > 3 mm, n = 150; size ≤ 3 mm, n = 310) were scanned with non-MIP iMSDE-TSE and non-MIP 3D-GRE. We then performed 5-mm MIP reconstruction of these images. Two independent neuroradiologists reviewed these four sequences. Their diagnostic performance was compared using the following parameters: sensitivity, reading time, and figure of merit (FOM) derived by jackknife alternative free-response receiver operating characteristic analysis. Interobserver agreement was also tested. The mean FOM (all lesions, 0.984; lesions ≤ 3 mm, 0.980) and sensitivity ([reader 1: all lesions, 97.3%; lesions ≤ 3 mm, 96.2%], [reader 2: all lesions, 97.0%; lesions ≤ 3 mm, 95.8%]) of MIP iMSDE-TSE was comparable to the mean FOM (0.985, 0.977) and sensitivity ([reader 1: 96.7, 99.0%], [reader 2: 97, 95.3%]) of non-MIP iMSDE-TSE, but they were superior to those of non-MIP and MIP 3D-GREs (all, p < 0.001). The reading time of MIP iMSDE-TSE (reader 1: 47.7 ± 35.9 seconds; reader 2: 44.7 ± 23.6 seconds) was significantly shorter than that of non-MIP iMSDE-TSE (reader 1: 78.8 ± 43.7 seconds, p = 0.01; reader 2: 82.9 ± 39.9 seconds, p < 0.001). Interobserver agreement was excellent (κ > 0.75) for all lesions in both sequences. MIP iMSDE-TSE showed high detectability of brain metastases. Its detectability was comparable to that of non-MIP iMSDE-TSE, but it was superior to the detectability of non-MIP/MIP 3D-GREs. With a shorter reading time, the false-positive results of MIP i
Alexenko, Andrei P; Mao, Jiude; Ellersieck, Mark R; Davis, Angela M; Whyte, Jeffrey J; Rosenfeld, Cheryl S; Roberts, R Michael
2007-10-01
Skewing of the sex ratio towards males occurs among pups born to mice fed a very high saturated fat (VHF) diet. In the present study, we tested whether the fat content of the VHF diet rather than the number of calories consumed is responsible for this effect. Eight-week-old NIH Swiss mice were placed on the VHF diet either ad libitum (VHF) or in a restricted manner (VHF-R). The VHF-R mice gained weight at a similar rate to controls fed a standard chow diet. Mice were bred at 15 wk and subsequently at 26 wk and 35 wk of age. Overall, the VHF, VHF-R, and control groups delivered 244, 242, and 274 pups, respectively, with male proportions of 0.60, 0.43, and 0.48, respectively. The pup sex ratios of the VHF group (favoring males) and VHF-R group (favoring females) each differed from 0.5 (P fat consumed. Since males fed the VHF diet had neither more Y-sperm nor sired more sons than daughters, the dietary effects are manifested exclusively through the female.
... Physician Resources Professions Site Index A-Z Contrast Materials What are contrast materials and how do they ... material? Pregnancy and contrast materials What are contrast materials and how do they work? Contrast materials, also ...
Optimal Portfolio Strategy under Rolling Economic Maximum Drawdown Constraints
Xiaojian Yu; Siyu Xie; Weijun Xu
2014-01-01
This paper deals with the problem of optimal portfolio strategy under the constraints of rolling economic maximum drawdown. A more practical strategy is developed by using rolling Sharpe ratio in computing the allocation proportion in contrast to existing models. Besides, another novel strategy named “REDP strategy” is further proposed, which replaces the rolling economic drawdown of the portfolio with the rolling economic drawdown of the risky asset. The simulation tests prove that REDP stra...
Honguero Martínez, A F; García Jiménez, M D; García Vicente, A; López-Torres Hidalgo, J; Colon, M J; van Gómez López, O; Soriano Castrejón, Á M; León Atance, P
2016-01-01
F-18 fluorodeoxyglucose integrated PET-CT scan is commonly used in the work-up of lung cancer to improve preoperative disease stage. The aim of the study was to analyze the ratio between SUVmax of N1 lymph nodes and primary lung cancer to establish prediction of mediastinal disease (N2) in patients operated on non-small cell lung cancer. This is a retrospective study of a prospective database. Patients operated on non-small cell lung cancer (NSCLC) with N1 disease by PET-CT scan were included. None of them had previous induction treatment, but they underwent standard surgical resection plus systematic lymphadenectomy. There were 51 patients with FDG-PET-CT scan N1 disease. 44 (86.3%) patients were male with a mean age of 64.1±10.8 years. Type of resection: pneumonectomy=4 (7.9%), lobectomy/bilobectomy=44 (86.2%), segmentectomy=3 (5.9%). adenocarcinoma=26 (51.0%), squamous=23 (45.1%), adenosquamous=2 (3.9%). Lymph nodes after surgical resection: N0=21 (41.2%), N1=12 (23.5%), N2=18 (35.3%). Mean ratio of the SUVmax of N1 lymph node to the SUVmax of the primary lung tumor (SUVmax N1/T ratio) was 0.60 (range 0.08-2.80). ROC curve analysis to obtain the optimal cut-off value of SUVmax N1/T ratio to predict N2 disease was performed. At multivariate analysis, we found that a ratio of 0.46 or greater was an independent predictor factor of N2 mediastinal lymph node metastases with a sensitivity and specificity of 77.8% and 69.7%, respectively. SUVmax N1/T ratio in NSCLC patients correlates with mediastinal lymph node metastasis (N2 disease) after surgical resection. When SUVmax N1/T ratio on integrated PET-CT scan is equal or superior to 0.46, special attention should be paid on higher probability of N2 disease. Copyright © 2015 Elsevier España, S.L.U. and SEMNIM. All rights reserved.
Hartmann, R. R. K.
This paper deals with the relation between etymologically related words in different languages. A survey is made of seven stages in the development of contrastive lexicology. These are: prelinguistic word studies, semantics, lexicography, translation, foreign language learning, bilingualism, and finally contrastive analysis. Concerning contrastive…
Maximum Autocorrelation Factorial Kriging
Nielsen, Allan Aasbjerg; Conradsen, Knut; Pedersen, John L.
2000-01-01
This paper describes maximum autocorrelation factor (MAF) analysis, maximum autocorrelation factorial kriging, and its application to irregularly sampled stream sediment geochemical data from South Greenland. Kriged MAF images are compared with kriged images of varimax rotated factors from...
Kozdon, R.; Kelly, D.; Fournelle, J.; Valley, J. W.
2012-12-01
Earth surface temperatures warmed by ~5°C during an ancient (~55.5 Ma) global warming event termed the Paleocene-Eocene thermal maximum (PETM). This transient (~200 ka) "hyperthermal" climate state had profound consequences for the planet's surficial processes and biosphere, and is widely touted as being an ancient analog for climate change driven by human activities. Hallmarks of the PETM are pervasive carbonate dissolution in the ocean basins and a negative carbon isotope excursion (CIE) recorded in variety of substrates including soil and marine carbonates. Together these lines of evidence signal the rapid (≤30 ka) release of massive quantities (≥2000 Gt) of 13C-depleted carbon into the exogenic carbon cycle. Paleoenvironmental reconstructions based on pedogenic features in paleosols, clay mineralogy and sedimentology of coastal and continental deposits, and land-plant communities indicate that PETM warmth was accompanied by a major perturbation to the hydrologic cycle. Micropaleontological evidence and n-alkane hydrogen isotope records indicate that increased poleward moisture transport reduced sea-surface salinities (SSSs) in the central Arctic Ocean during the PETM. Such findings are broadly consistent with predictions of climate model simulations. Here we reassess a well-studied PETM record from the Southern Ocean (ODP Site 690) in light of new δ18O and Mg/Ca data obtained from planktic foraminiferal shells by secondary ion mass spectrometry (SIMS) and electron microprobe analysis (EMPA), respectively. The unparalleled spatial resolution of these in situ techniques permits extraction of more reliable δ18O and Mg/Ca data by targeting of minute (≤10 μm spots), biogenic domains within individual planktic foraminifera that retain the original shell chemistry (Kozdon et al. 2011, Paleocean.). In general, the stratigraphic profile and magnitude of the δ18O decrease (~2.2‰) delimiting PETM warming in our SIMS-generated record are similar to those of
Maximum margin Bayesian network classifiers.
Pernkopf, Franz; Wohlmayr, Michael; Tschiatschek, Sebastian
2012-03-01
We present a maximum margin parameter learning algorithm for Bayesian network classifiers using a conjugate gradient (CG) method for optimization. In contrast to previous approaches, we maintain the normalization constraints on the parameters of the Bayesian network during optimization, i.e., the probabilistic interpretation of the model is not lost. This enables us to handle missing features in discriminatively optimized Bayesian networks. In experiments, we compare the classification performance of maximum margin parameter learning to conditional likelihood and maximum likelihood learning approaches. Discriminative parameter learning significantly outperforms generative maximum likelihood estimation for naive Bayes and tree augmented naive Bayes structures on all considered data sets. Furthermore, maximizing the margin dominates the conditional likelihood approach in terms of classification performance in most cases. We provide results for a recently proposed maximum margin optimization approach based on convex relaxation. While the classification results are highly similar, our CG-based optimization is computationally up to orders of magnitude faster. Margin-optimized Bayesian network classifiers achieve classification performance comparable to support vector machines (SVMs) using fewer parameters. Moreover, we show that unanticipated missing feature values during classification can be easily processed by discriminatively optimized Bayesian network classifiers, a case where discriminative classifiers usually require mechanisms to complete unknown feature values in the data first.
Optimization of phase contrast in bimodal amplitude modulation AFM
Mehrnoosh Damircheli
2015-04-01
Full Text Available Bimodal force microscopy has expanded the capabilities of atomic force microscopy (AFM by providing high spatial resolution images, compositional contrast and quantitative mapping of material properties without compromising the data acquisition speed. In the first bimodal AFM configuration, an amplitude feedback loop keeps constant the amplitude of the first mode while the observables of the second mode have not feedback restrictions (bimodal AM. Here we study the conditions to enhance the compositional contrast in bimodal AM while imaging heterogeneous materials. The contrast has a maximum by decreasing the amplitude of the second mode. We demonstrate that the roles of the excited modes are asymmetric. The operational range of bimodal AM is maximized when the second mode is free to follow changes in the force. We also study the contrast in trimodal AFM by analyzing the kinetic energy ratios. The phase contrast improves by decreasing the energy of second mode relative to those of the first and third modes.
Optimization of phase contrast in bimodal amplitude modulation AFM.
Damircheli, Mehrnoosh; Payam, Amir F; Garcia, Ricardo
2015-01-01
Bimodal force microscopy has expanded the capabilities of atomic force microscopy (AFM) by providing high spatial resolution images, compositional contrast and quantitative mapping of material properties without compromising the data acquisition speed. In the first bimodal AFM configuration, an amplitude feedback loop keeps constant the amplitude of the first mode while the observables of the second mode have not feedback restrictions (bimodal AM). Here we study the conditions to enhance the compositional contrast in bimodal AM while imaging heterogeneous materials. The contrast has a maximum by decreasing the amplitude of the second mode. We demonstrate that the roles of the excited modes are asymmetric. The operational range of bimodal AM is maximized when the second mode is free to follow changes in the force. We also study the contrast in trimodal AFM by analyzing the kinetic energy ratios. The phase contrast improves by decreasing the energy of second mode relative to those of the first and third modes.
Wang, Fang; Nojima, Masanori; Inoue, Yusuke; Ohtomo, Kuni; Kiryu, Shigeru
2015-01-01
It is not known whether administration of contrast agent via retro-orbital injection or the tail vein route affects the efficiency of dynamic contrast-enhanced magnetic resonance imaging (MRI). Therefore, we compared the effects of retro-orbital and tail vein injection on the kinetics of the contrast agent used for MRI in mice. The same group of nine healthy female mice received contrast agent via either route. An extracellular contrast agent was infused via the tail vein and retro-orbital vein, in random order. Dynamic contrast-enhanced MRI was performed before and after administering the contrast agent. The contrast effects in the liver, kidney, lung, and myocardium were assessed. The average total times of venous puncture and mounting of the injection system were about 10 and 4 min for the tail vein and retro-orbital route, respectively. For all organs assessed, the maximum contrast ratio occurred 30 s after administration and the time course of the contrast ratio was similar with either routes. For each organ, the contrast ratios correlated strongly; the contrast ratios were similar. The retro-orbital and tail vein routes afforded similar results in terms of the kinetics of the contrast agent. The retro-orbital route can be used as a simple efficient alternative to tail vein injection for dynamic contrast-enhanced MRI of mice.
Fang Wang
Full Text Available It is not known whether administration of contrast agent via retro-orbital injection or the tail vein route affects the efficiency of dynamic contrast-enhanced magnetic resonance imaging (MRI. Therefore, we compared the effects of retro-orbital and tail vein injection on the kinetics of the contrast agent used for MRI in mice. The same group of nine healthy female mice received contrast agent via either route. An extracellular contrast agent was infused via the tail vein and retro-orbital vein, in random order. Dynamic contrast-enhanced MRI was performed before and after administering the contrast agent. The contrast effects in the liver, kidney, lung, and myocardium were assessed. The average total times of venous puncture and mounting of the injection system were about 10 and 4 min for the tail vein and retro-orbital route, respectively. For all organs assessed, the maximum contrast ratio occurred 30 s after administration and the time course of the contrast ratio was similar with either routes. For each organ, the contrast ratios correlated strongly; the contrast ratios were similar. The retro-orbital and tail vein routes afforded similar results in terms of the kinetics of the contrast agent. The retro-orbital route can be used as a simple efficient alternative to tail vein injection for dynamic contrast-enhanced MRI of mice.
史海芳; 李树有; 姬永刚
2008-01-01
For two normal populations with u~nown means μi and variances σ2i>0,i=1,2,assume that there is a semi-order restriction between ratios of means and standard deviations and sample numbers of two normal populations are different.A procedure of obtaining the maximum likelihood estimatom of μi's and σ's under the semi-order restrictions is proposed.For i=3 case,some connected results and simulations are given.
Optimal Portfolio Strategy under Rolling Economic Maximum Drawdown Constraints
Xiaojian Yu
2014-01-01
Full Text Available This paper deals with the problem of optimal portfolio strategy under the constraints of rolling economic maximum drawdown. A more practical strategy is developed by using rolling Sharpe ratio in computing the allocation proportion in contrast to existing models. Besides, another novel strategy named “REDP strategy” is further proposed, which replaces the rolling economic drawdown of the portfolio with the rolling economic drawdown of the risky asset. The simulation tests prove that REDP strategy can ensure the portfolio to satisfy the drawdown constraint and outperforms other strategies significantly. An empirical comparison research on the performances of different strategies is carried out by using the 23-year monthly data of SPTR, DJUBS, and 3-month T-bill. The investment cases of single risky asset and two risky assets are both studied in this paper. Empirical results indicate that the REDP strategy successfully controls the maximum drawdown within the given limit and performs best in both return and risk.
Maximum Likelihood Fusion Model
2014-08-09
by the DLR Institute of Robotics and Mechatronics building (dataset courtesy of the University of Bre- men). In contrast to the Victoria Park dataset...Institute of Robotics and Mechatronics building (dataset courtesy of the University of Bremen). In contrast to the Victoria Park dataset, a camera sensor is
Maximum Autocorrelation Factorial Kriging
Nielsen, Allan Aasbjerg; Conradsen, Knut; Pedersen, John L.; Steenfelt, Agnete
2000-01-01
This paper describes maximum autocorrelation factor (MAF) analysis, maximum autocorrelation factorial kriging, and its application to irregularly sampled stream sediment geochemical data from South Greenland. Kriged MAF images are compared with kriged images of varimax rotated factors from an ordinary non-spatial factor analysis, and they are interpreted in a geological context. It is demonstrated that MAF analysis contrary to ordinary non-spatial factor analysis gives an objective discrimina...
Spectral phase-contrast CT using the LAMBDA detector
Ehn, Sebastian; Epple, Michael; Potdevin, Guillaume; Renker, Dieter; Pfeiffer, Franz [Chair of Biomedical Physics, TU Muenchen (Germany); Pennicard, David; Smoljanin, Sergej; Lange, Sabine; Graafsma, Heinz [DESY, Hamburg (Germany)
2013-07-01
X-ray phase-contrast techniques offer significantly improved soft-tissue contrast compared to absorption-based measurements commonly used in clinical radiology. Grating-based phase contrast methods have proven to be fully compatible to standard laboratory X-ray sources and are currently being used in preclinical research. However, the imaging quality in this method is strongly energy-dependent, which may result in poor signal to noise ratios when using beams with broad energy spectra. One can overcome this disadvantage using energy sensitive detectors like the Medipix3, only taking into account the energies where the SNR is at a maximum. Thereby, an improvement to image quality and a reduction in radiation dose may be reached. This presentation will give an overview over the new Medipix3-based LAMBDA detector, which is currently being developed at DESY, used in grating-based spectral phase-contrast tomography.
Maximum likely scale estimation
Loog, Marco; Pedersen, Kim Steenstrup; Markussen, Bo
2005-01-01
A maximum likelihood local scale estimation principle is presented. An actual implementation of the estimation principle uses second order moments of multiple measurements at a fixed location in the image. These measurements consist of Gaussian derivatives possibly taken at several scales and/or ...
Maximum information photoelectron metrology
Hockett, P; Wollenhaupt, M; Baumert, T
2015-01-01
Photoelectron interferograms, manifested in photoelectron angular distributions (PADs), are a high-information, coherent observable. In order to obtain the maximum information from angle-resolved photoionization experiments it is desirable to record the full, 3D, photoelectron momentum distribution. Here we apply tomographic reconstruction techniques to obtain such 3D distributions from multiphoton ionization of potassium atoms, and fully analyse the energy and angular content of the 3D data. The PADs obtained as a function of energy indicate good agreement with previous 2D data and detailed analysis [Hockett et. al., Phys. Rev. Lett. 112, 223001 (2014)] over the main spectral features, but also indicate unexpected symmetry-breaking in certain regions of momentum space, thus revealing additional continuum interferences which cannot otherwise be observed. These observations reflect the presence of additional ionization pathways and, most generally, illustrate the power of maximum information measurements of th...
Francescon, Paolo, E-mail: paolo.francescon@ulssvicenza.it; Satariano, Ninfa [Department of Radiation Oncology, Ospedale Di Vicenza, Viale Rodolfi, Vicenza 36100 (Italy); Beddar, Sam [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77005 (United States); Das, Indra J. [Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana 46202 (United States)
2014-10-15
Purpose: Evaluate the ability of different dosimeters to correctly measure the dosimetric parameters percentage depth dose (PDD), tissue-maximum ratio (TMR), and off-axis ratio (OAR) in water for small fields. Methods: Monte Carlo (MC) simulations were used to estimate the variation of k{sub Q{sub c{sub l{sub i{sub n,Q{sub m{sub s{sub r}{sup f{sub c}{sub l}{sub i}{sub n},f{sub m}{sub s}{sub r}}}}}}}}} for several types of microdetectors as a function of depth and distance from the central axis for PDD, TMR, and OAR measurements. The variation of k{sub Q{sub c{sub l{sub i{sub n,Q{sub m{sub s{sub r}{sup f{sub c}{sub l}{sub i}{sub n},f{sub m}{sub s}{sub r}}}}}}}}} enables one to evaluate the ability of a detector to reproduce the PDD, TMR, and OAR in water and consequently determine whether it is necessary to apply correction factors. The correctness of the simulations was verified by assessing the ratios between the PDDs and OARs of 5- and 25-mm circular collimators used with a linear accelerator measured with two different types of dosimeters (the PTW 60012 diode and PTW PinPoint 31014 microchamber) and the PDDs and the OARs measured with the Exradin W1 plastic scintillator detector (PSD) and comparing those ratios with the corresponding ratios predicted by the MC simulations. Results: MC simulations reproduced results with acceptable accuracy compared to the experimental results; therefore, MC simulations can be used to successfully predict the behavior of different dosimeters in small fields. The Exradin W1 PSD was the only dosimeter that reproduced the PDDs, TMRs, and OARs in water with high accuracy. With the exception of the EDGE diode, the stereotactic diodes reproduced the PDDs and the TMRs in water with a systematic error of less than 2% at depths of up to 25 cm; however, they produced OAR values that were significantly different from those in water, especially in the tail region (lower than 20% in some cases). The microchambers could be used for PDD
Maximum Likelihood Associative Memories
Gripon, Vincent; Rabbat, Michael
2013-01-01
Associative memories are structures that store data in such a way that it can later be retrieved given only a part of its content -- a sort-of error/erasure-resilience property. They are used in applications ranging from caches and memory management in CPUs to database engines. In this work we study associative memories built on the maximum likelihood principle. We derive minimum residual error rates when the data stored comes from a uniform binary source. Second, we determine the minimum amo...
Maximum likely scale estimation
Loog, Marco; Pedersen, Kim Steenstrup; Markussen, Bo
2005-01-01
A maximum likelihood local scale estimation principle is presented. An actual implementation of the estimation principle uses second order moments of multiple measurements at a fixed location in the image. These measurements consist of Gaussian derivatives possibly taken at several scales and....../or having different derivative orders. Although the principle is applicable to a wide variety of image models, the main focus here is on the Brownian model and its use for scale selection in natural images. Furthermore, in the examples provided, the simplifying assumption is made that the behavior...... of the measurements is completely characterized by all moments up to second order....
F. TopsÃƒÂ¸e
2001-09-01
Full Text Available Abstract: In its modern formulation, the Maximum Entropy Principle was promoted by E.T. Jaynes, starting in the mid-fifties. The principle dictates that one should look for a distribution, consistent with available information, which maximizes the entropy. However, this principle focuses only on distributions and it appears advantageous to bring information theoretical thinking more prominently into play by also focusing on the "observer" and on coding. This view was brought forward by the second named author in the late seventies and is the view we will follow-up on here. It leads to the consideration of a certain game, the Code Length Game and, via standard game theoretical thinking, to a principle of Game Theoretical Equilibrium. This principle is more basic than the Maximum Entropy Principle in the sense that the search for one type of optimal strategies in the Code Length Game translates directly into the search for distributions with maximum entropy. In the present paper we offer a self-contained and comprehensive treatment of fundamentals of both principles mentioned, based on a study of the Code Length Game. Though new concepts and results are presented, the reading should be instructional and accessible to a rather wide audience, at least if certain mathematical details are left aside at a rst reading. The most frequently studied instance of entropy maximization pertains to the Mean Energy Model which involves a moment constraint related to a given function, here taken to represent "energy". This type of application is very well known from the literature with hundreds of applications pertaining to several different elds and will also here serve as important illustration of the theory. But our approach reaches further, especially regarding the study of continuity properties of the entropy function, and this leads to new results which allow a discussion of models with so-called entropy loss. These results have tempted us to speculate over
Regularized maximum correntropy machine
Wang, Jim Jing-Yan
2015-02-12
In this paper we investigate the usage of regularized correntropy framework for learning of classifiers from noisy labels. The class label predictors learned by minimizing transitional loss functions are sensitive to the noisy and outlying labels of training samples, because the transitional loss functions are equally applied to all the samples. To solve this problem, we propose to learn the class label predictors by maximizing the correntropy between the predicted labels and the true labels of the training samples, under the regularized Maximum Correntropy Criteria (MCC) framework. Moreover, we regularize the predictor parameter to control the complexity of the predictor. The learning problem is formulated by an objective function considering the parameter regularization and MCC simultaneously. By optimizing the objective function alternately, we develop a novel predictor learning algorithm. The experiments on two challenging pattern classification tasks show that it significantly outperforms the machines with transitional loss functions.
Minimum Length - Maximum Velocity
Panes, Boris
2011-01-01
We study a framework where the hypothesis of a minimum length in space-time is complemented with the notion of reference frame invariance. It turns out natural to interpret the action of the obtained reference frame transformations in the context of doubly special relativity. As a consequence of this formalism we find interesting connections between the minimum length properties and the modified velocity-energy relation for ultra-relativistic particles. For example we can predict the ratio between the minimum lengths in space and time using the results from OPERA about superluminal neutrinos.
Equalized near maximum likelihood detector
2012-01-01
This paper presents new detector that is used to mitigate intersymbol interference introduced by bandlimited channels. This detector is named equalized near maximum likelihood detector which combines nonlinear equalizer and near maximum likelihood detector. Simulation results show that the performance of equalized near maximum likelihood detector is better than the performance of nonlinear equalizer but worse than near maximum likelihood detector.
Cheeseman, Peter; Stutz, John
2005-01-01
A long standing mystery in using Maximum Entropy (MaxEnt) is how to deal with constraints whose values are uncertain. This situation arises when constraint values are estimated from data, because of finite sample sizes. One approach to this problem, advocated by E.T. Jaynes [1], is to ignore this uncertainty, and treat the empirically observed values as exact. We refer to this as the classic MaxEnt approach. Classic MaxEnt gives point probabilities (subject to the given constraints), rather than probability densities. We develop an alternative approach that assumes that the uncertain constraint values are represented by a probability density {e.g: a Gaussian), and this uncertainty yields a MaxEnt posterior probability density. That is, the classic MaxEnt point probabilities are regarded as a multidimensional function of the given constraint values, and uncertainty on these values is transmitted through the MaxEnt function to give uncertainty over the MaXEnt probabilities. We illustrate this approach by explicitly calculating the generalized MaxEnt density for a simple but common case, then show how this can be extended numerically to the general case. This paper expands the generalized MaxEnt concept introduced in a previous paper [3].
Kingdom, F A; Whittle, P
1996-03-01
Previous measurements of contrast discrimination threshold, delta C, as a function of pedestal contrast, C, for sine-wave gratings have shown a power law relationship between delta C and C at suprathreshold levels of C. However, these studies have rarely used contrasts greater than 50%. Whittle (1986), using incremental and decremental patches, found that delta C increased with C only up to about 50%. At higher contrasts it decreased. Since a periodic stimulus can be considered to be composed of increments and decrements, we thought we might find such an inverse U-shaped function for gratings if we used contrasts up to 100%. We tested this for both sine-wave and square-wave stimuli at spatial frequencies from 0.0625 to 8.0 c/deg. We found that for frequencies up to 0.5 c/deg, delta C in nearly all cases 'dipped down' after about C = 50% contrast. At 4.0 and 8.0 c/deg, however, no dip-down occurred. Additional experiments showed that the dip-down was unlikely to be due to cortical long-term adaptation and most likely an effect of localized light adaptation to the dark bars. We argue that the absence of dip-down at high spatial frequencies was mainly due to the attenuation of contrast by the optics of the eye. As for the results of Whittle (1986), a Weber's Law in W = (Lmax-Lmin)/Lmin describes the inverse U-shaped contrast discrimination function well. Two other contrast expressions also linearize the data on log-log plots. We show how some familiar notions about the physiological operation of localized light adaptation can easily account for the form of the contrast discrimination function. Finally we estimate the number of discriminable steps in contrast from detection threshold to maximum contrast for the various spatial frequencies tested.
赵连成; 彭亚光; 李莹; 李响; 李淑红; 武阳丰
2013-01-01
目的 评价用腰围(WC)和腰围身高比(WHtR)预测中国中年人群中心性肥胖的效果和差异.方法 选用国家“八五”和“九五”攻关课题的两次横断面调查共30 630名35～59岁人群资料,按不同身高分组,根据诊断中心性肥胖的WC切点(男性≥85 cm,女性≥80 cm)和WHtR的切点(≥0.50),比较预测中心性肥胖的一致性,并计算心血管病危险因素(包括高血压、空腹血糖异常、血清总胆固醇升高及血清高密度脂蛋白胆固醇降低)聚集(危险因素个数≥2)的灵敏度和特异度等诊断学指标.结果 WC与WHtR在男女性人群中预测中心性肥胖的一致性较高,Kappa值分别为0.805和0.816.但在身高较低(男性＜160 cm,女性＜150 cm)或身高较高(男性≥180 cm,女性≥170 cm)人群中,两指标预测的一致性较差(Kappa值均≤0.6).以WC诊断切点预测危险因素聚集,在男女性身高较低人群中,其灵敏度均较低,而在身高较高的人群中,特异度均较低；而用WHtR诊断切点预测危险因素聚集,在不同身高组中预测的灵敏度(男性为56.1％～64.1％,女性为64.7％～ 73.2％)和特异度(男性为70.0％～74.5％,女性为59.2％ ～ 75.9％)均较好,且波动范围较小.结论 在全人群中,男女性WC和WHtR对预测心血管病危险因素聚集,评价中心性肥胖预测效果相当；但在身高较低或较高的人群中,WHtR的预测效果优于WC.%Objective To study the efficacy of waist circumference (WC) and waist-to-height ratio (WHtR) in predicting central obesity among the Chinese adult population.Methods A total of 30 630 participants aged 35-59 from different areas in mainland China were surveyed for the risk factors of cardiovascular diseases (CVD) in two independent cross-sectional studies that were carried out in 1992-1994 and 1998,respectively.In subgroups with different heights,consistency analysis for central obesity diagnosed by WHtR (≥0.50) and WC (≥85 cm for men
Creep measurements confirm steady flow after stress maximum in extension of branched polymer melts
Javier Alvarez, Nicolas; Román Marín, José Manuel; Huang, Qian;
2013-01-01
We provide conclusive evidence of nonmonotonic mechanical behavior in the extension of long-chain branched polymer melts. While nonmonotonic behavior is known to occur for solids, for the case of polymeric melts, this phenomenon is in direct contrast with current theoretical models. We rule out...... the possibility of the overshoot being an experimental artifact by confirming the existence of steady flow after a maximum in the ratio of stress to strain rate versus strain under both constant stress and constant strain-rate kinematics. This observation indicates the omission of important physics from current...
Adaptive speckle reduction of ultrasound images based on maximum likelihood estimation
Xu Liu(刘旭); Yongfeng Huang(黄永锋); Wende Shou(寿文德); Tao Ying(应涛)
2004-01-01
A method has been developed in this paper to gain effective speckle reduction in medical ultrasound images.To exploit full knowledge of the speckle distribution, here maximum likelihood was used to estimate speckle parameters corresponding to its statistical mode. Then the results were incorporated into the nonlinear anisotropic diffusion to achieve adaptive speckle reduction. Verified with simulated and ultrasound images,we show that this algorithm is capable of enhancing features of clinical interest and reduces speckle noise more efficiently than just applying classical filters. To avoid edge contribution, changes of contrast-to-noise ratio of different regions are also compared to investigate the performance of this approach.
Yatsuyanagi, Eiji; Sato, Kazuhiro; Kikuchi, Keisuke; Saito, Hirotsugu
2014-02-01
To define the accuracy of pulmonary arterial blood flow (PA-flow) measured by phase contrast magnetic resonance imaging (PC-MRI), we compared the PA-flow data of PC-MRI with the data of perfusion-ventilation lung scintigraphy. Eighteen patients who preoperatively underwent PA-flow measurement using PC-MRI and perfusion-ventilation lung scintigraphy were evaluated. The PA-flow (cm3/sec) of MRI was calculated by multiplying maximum velocity (cm/sec) by region of interest (ROI) area (cm2) of measured main pulmonary artery using phase contrast method. The left to right ratio (R/L ratio) of PA-flow measured by PC-MRI was compared with the R/L ratios of the date of perfusion-ventilation lung scintigraphy. The R/L ratios of PC-MRI and perfusion lung scintigraphy were 1.43 ± 1.07 and 1.35 ± 0.82, respectively. Both ratios showed excellent correlation( y=-0.50+1.30x, r=0.99,pperfusion lung scintigraphy in the patients with a past history of lung resection, even if their R/L ratios of perfusion lung scintigraphy differed from those of ventilation lung scintigraphy. These results revealed that the PA-flow could be accurately measured by PC-MRI without contrast medium and nuclear medicine instruments.
Evaluation of pliers' grip spans in the maximum gripping task and sub-maximum cutting task.
Kim, Dae-Min; Kong, Yong-Ku
2016-12-01
A total of 25 males participated to investigate the effects of the grip spans of pliers on the total grip force, individual finger forces and muscle activities in the maximum gripping task and wire-cutting tasks. In the maximum gripping task, results showed that the 50-mm grip span had significantly higher total grip strength than the other grip spans. In the cutting task, the 50-mm grip span also showed significantly higher grip strength than the 65-mm and 80-mm grip spans, whereas the muscle activities showed a higher value at 80-mm grip span. The ratios of cutting force to maximum grip strength were also investigated. Ratios of 30.3%, 31.3% and 41.3% were obtained by grip spans of 50-mm, 65-mm, and 80-mm, respectively. Thus, the 50-mm grip span for pliers might be recommended to provide maximum exertion in gripping tasks, as well as lower maximum-cutting force ratios in the cutting tasks.
Vestige: Maximum likelihood phylogenetic footprinting
Maxwell Peter
2005-05-01
Full Text Available Abstract Background Phylogenetic footprinting is the identification of functional regions of DNA by their evolutionary conservation. This is achieved by comparing orthologous regions from multiple species and identifying the DNA regions that have diverged less than neutral DNA. Vestige is a phylogenetic footprinting package built on the PyEvolve toolkit that uses probabilistic molecular evolutionary modelling to represent aspects of sequence evolution, including the conventional divergence measure employed by other footprinting approaches. In addition to measuring the divergence, Vestige allows the expansion of the definition of a phylogenetic footprint to include variation in the distribution of any molecular evolutionary processes. This is achieved by displaying the distribution of model parameters that represent partitions of molecular evolutionary substitutions. Examination of the spatial incidence of these effects across regions of the genome can identify DNA segments that differ in the nature of the evolutionary process. Results Vestige was applied to a reference dataset of the SCL locus from four species and provided clear identification of the known conserved regions in this dataset. To demonstrate the flexibility to use diverse models of molecular evolution and dissect the nature of the evolutionary process Vestige was used to footprint the Ka/Ks ratio in primate BRCA1 with a codon model of evolution. Two regions of putative adaptive evolution were identified illustrating the ability of Vestige to represent the spatial distribution of distinct molecular evolutionary processes. Conclusion Vestige provides a flexible, open platform for phylogenetic footprinting. Underpinned by the PyEvolve toolkit, Vestige provides a framework for visualising the signatures of evolutionary processes across the genome of numerous organisms simultaneously. By exploiting the maximum-likelihood statistical framework, the complex interplay between mutational
The maximum rotation of a galactic disc
Bottema, R
1997-01-01
The observed stellar velocity dispersions of galactic discs show that the maximum rotation of a disc is on average 63% of the observed maximum rotation. This criterion can, however, not be applied to small or low surface brightness (LSB) galaxies because such systems show, in general, a continuously rising rotation curve until the outermost measured radial position. That is why a general relation has been derived, giving the maximum rotation for a disc depending on the luminosity, surface brightness, and colour of the disc. As a physical basis of this relation serves an adopted fixed mass-to-light ratio as a function of colour. That functionality is consistent with results from population synthesis models and its absolute value is determined from the observed stellar velocity dispersions. The derived maximum disc rotation is compared with a number of observed maximum rotations, clearly demonstrating the need for appreciable amounts of dark matter in the disc region and even more so for LSB galaxies. Matters h...
Multimodal nanoparticulate bioimaging contrast agents.
Sharma, Parvesh; Singh, Amit; Brown, Scott C; Bengtsson, Niclas; Walter, Glenn A; Grobmyer, Stephen R; Iwakuma, Nobutaka; Santra, Swadeshmukul; Scott, Edward W; Moudgil, Brij M
2010-01-01
A wide variety of bioimaging techniques (e.g., ultrasound, computed X-ray tomography, magnetic resonance imaging (MRI), and positron emission tomography) are commonly employed for clinical diagnostics and scientific research. While all of these methods use a characteristic "energy-matter" interaction to provide specific details about biological processes, each modality differs from another in terms of spatial and temporal resolution, anatomical and molecular details, imaging depth, as well as the desirable material properties of contrast agents needed for augmented imaging. On many occasions, it is advantageous to apply multiple complimentary imaging modalities for faster and more accurate prognosis. Since most imaging modalities employ exogenous contrast agents to improve the signal-to-noise ratio, the development and use of multimodal contrast agents is considered to be highly advantageous for obtaining improved imagery from sought-after imaging modalities. Multimodal contrast agents offer improvements in patient care, and at the same time can reduce costs and enhance safety by limiting the number of contrast agent administrations required for imaging purposes. Herein, we describe the synthesis and characterization of nanoparticulate-based multimodal contrast agent for noninvasive bioimaging using MRI, optical, and photoacoustic tomography (PAT)-imaging modalities. The synthesis of these agents is described using microemulsions, which enable facile integration of the desired diversity of contrast agents and material components into a single entity.
Contrast induced nephropathy in urology
Viji Samuel Thomson
2009-01-01
Full Text Available Intravenous contrast agents have a distinct role in urological imaging: to study precise anatomical delineation, vascularity, and to assess the function of the renal unit. Contrast induced nephropathy (CIN is a known adverse effect of intravenous contrast administration. The literature on incidence, pathophysiology, clinical features, and current preventive strategies available for CIN relevant to urologists was reviewed. A search of the PubMed database was done using the keywords nephropathy and media, prevention and control or prevention Contrast media (explode, all adverse effects, and kidney diseases (explode. An online search of the EMBASE database for the time ranging from 1977 to February 2009 was performed using the keywords ionic contrast medium, adverse drug reaction, major or controlled clinical study, human, nephrotoxicity, and kidney disease. Current publications and data most relevant to urologists were examined. CIN was the third most common cause of hospital-acquired renal failure. The incidence is less common with intravenous contrast administration as compared with intra-arterial administration. The pathogenesis of contrast mediated nephropathy is due to a combination of toxic injury to renal tubules and medullary ischemic injury mediated by reactive oxygen species. CIN most commonly manifests as a nonoliguric and asymptomatic transient decline in renal function. Patients who developed CIN were found to have increased mortality, longer hospital stay, and complicated clinical course. An overview of risk factors and risk prediction score for prognostication of CIN are elaborated. Preventive strategies including choice of contrast agents, maximum tolerated dose, role of hydration, hydration regime, etc. are discussed. The role of N- acetyl cysteine, Theophylline, Fenoldapam, Endothelin receptor antagonists, iloprost, atrial natriuretic peptide, and newer therapies such as targeted renal therapy (TRT are discussed. A working
Parametric optimization of thermoelectric elements footprint for maximum power generation
Rezania, A.; Rosendahl, Lasse; Yin, Hao
2014-01-01
The development studies in thermoelectric generator (TEG) systems are mostly disconnected to parametric optimization of the module components. In this study, optimum footprint ratio of n- and p-type thermoelectric (TE) elements is explored to achieve maximum power generation, maximum cost-perform...
Contrast-to-noise in X-ray differential phase contrast imaging
Engel, K.J.; Geller, D.; Koehler, T.; Martens, G.; Schusser, S.; Vogtmeier, G.; Roessl, E.
2011-01-01
A quantitative theory for the contrast-to-noise ratio (CNR) in differential phase contrast imaging (DPCI) is proposed and compared to that of images derived from classical absorption contrast imaging (ACI). Most prominently, the CNR for DPCI contains the reciprocal of thespatial wavelength to be ima
Analysis of Photovoltaic Maximum Power Point Trackers
Veerachary, Mummadi
The photovoltaic generator exhibits a non-linear i-v characteristic and its maximum power point (MPP) varies with solar insolation. An intermediate switch-mode dc-dc converter is required to extract maximum power from the photovoltaic array. In this paper buck, boost and buck-boost topologies are considered and a detailed mathematical analysis, both for continuous and discontinuous inductor current operation, is given for MPP operation. The conditions on the connected load values and duty ratio are derived for achieving the satisfactory maximum power point operation. Further, it is shown that certain load values, falling out of the optimal range, will drive the operating point away from the true maximum power point. Detailed comparison of various topologies for MPPT is given. Selection of the converter topology for a given loading is discussed. Detailed discussion on circuit-oriented model development is given and then MPPT effectiveness of various converter systems is verified through simulations. Proposed theory and analysis is validated through experimental investigations.
Differential contrast of gold nanorods in dual-band OCT using spectral multiplexing
Al Rawashdeh, Wa’el [RWTH Aachen University, Experimental Molecular Imaging (Germany); Weyand, Thomas [DWI - Leibniz-Institute for Interactive Materials e.V. at RWTH Aachen University (Germany); Kray, Stefan; Lenz, Markus [RWTH Aachen University, Institute of Semiconductor Electronics (Germany); Buchkremer, Anne [RWTH Aachen University, Institut für Anorganische Chemie (Germany); Spöler, Felix [RWTH Aachen University, Institute of Semiconductor Electronics (Germany); Simon, Ulrich [RWTH Aachen University, Institut für Anorganische Chemie (Germany); Möller, Martin [DWI - Leibniz-Institute for Interactive Materials e.V. at RWTH Aachen University (Germany); Kiessling, Fabian; Lederle, Wiltrud, E-mail: wlederle@ukaachen.de [RWTH Aachen University, Experimental Molecular Imaging (Germany)
2015-03-15
In optical coherence tomography (OCT), differential contrast can be generated by resonant nanoparticles using spectral multiplexing. Differential contrast can be of interest for medical applications for improving detection specificity of structures with low endogenous contrast. Differential contrast has been shown using OCT systems with one bandwidth; however, this requires post-processing that is time consuming and reduces image resolution. In this study, we used a dual-band OCT prototype system with two far separated bandwidths in the clinically relevant optical window, and in search for the optimal differential contrast-generating particles for this prototype system, three different gold nanorods (AuNR) samples were investigated. The samples with different particle volume, aspect ratio, and absorption-maximum were imaged in a highly scattering phantom and on chicken muscle. In vitro, differential contrast was observed for the nanorods large (NRL) sample having the absorption-maximum within one bandwidth of the OCT and an average length of 75 nm. For the smaller AuNR (48 nm length) with comparable absorption-maximum, the obtained signal intensities were too low for being visible, although differences in signal intensities between both bandwidths could be measured. NRL optimal concentration for differential contrast using this prototype system is between 100 and 500 µg Au/mL (0.51–2.54 mM). These results demonstrate the potential of real-time imaging of differential contrast in dual-band OCT and motivate in vivo application of plasmon resonant AuNR in order to improve the detection sensitivity for structures that are difficult to identify by OCT such as small blood vessels.
OECD Maximum Residue Limit Calculator
With the goal of harmonizing the calculation of maximum residue limits (MRLs) across the Organisation for Economic Cooperation and Development, the OECD has developed an MRL Calculator. View the calculator.
The Maximum Resource Bin Packing Problem
Boyar, J.; Epstein, L.; Favrholdt, L.M.
2006-01-01
algorithms, First-Fit-Increasing and First-Fit-Decreasing for the maximum resource variant of classical bin packing. For the on-line variant, we define maximum resource variants of classical and dual bin packing. For dual bin packing, no on-line algorithm is competitive. For classical bin packing, we find......Usually, for bin packing problems, we try to minimize the number of bins used or in the case of the dual bin packing problem, maximize the number or total size of accepted items. This paper presents results for the opposite problems, where we would like to maximize the number of bins used...... the competitive ratio of various natural algorithms. We study the general versions of the problems as well as the parameterized versions where there is an upper bound of on the item sizes, for some integer k....
A Maximum Radius for Habitable Planets.
Alibert, Yann
2015-09-01
We compute the maximum radius a planet can have in order to fulfill two constraints that are likely necessary conditions for habitability: 1- surface temperature and pressure compatible with the existence of liquid water, and 2- no ice layer at the bottom of a putative global ocean, that would prevent the operation of the geologic carbon cycle to operate. We demonstrate that, above a given radius, these two constraints cannot be met: in the Super-Earth mass range (1-12 Mearth), the overall maximum that a planet can have varies between 1.8 and 2.3 Rearth. This radius is reduced when considering planets with higher Fe/Si ratios, and taking into account irradiation effects on the structure of the gas envelope.
Lesion Contrast Enhancement in Medical Ultrasound Imaging
Stetson, Paul F.; Sommer, F.G.; Macovski, A.
1997-01-01
Methods for improving the contrast-to-noise ratio (CNR) of low-contrast lesions in medical ultrasound imaging are described. Differences in the frequency spectra and amplitude distributions of the lesion and its surroundings can be used to increase the CNR of the lesion relative to the background...
Multi-Channel Maximum Likelihood Pitch Estimation
Christensen, Mads Græsbøll
2012-01-01
In this paper, a method for multi-channel pitch estimation is proposed. The method is a maximum likelihood estimator and is based on a parametric model where the signals in the various channels share the same fundamental frequency but can have different amplitudes, phases, and noise characteristics....... This essentially means that the model allows for different conditions in the various channels, like different signal-to-noise ratios, microphone characteristics and reverberation. Moreover, the method does not assume that a certain array structure is used but rather relies on a more general model and is hence...
Ricardo A. García Hernández
2016-06-01
Full Text Available Contrast-induced nephropathy is an important complication associated with the use of contrast media. Favoring factors for the development of contrast-induced nephronpathy have been widely described, being diabetes mellitus and previous renal disease the greatest risk. The pathophysiology is a complex process where the medullary hypoxia represents the trigger element. Previous hydration and the use of low osmolality contrast are the most recommended measures to prevent its development.
Maximum Entropy in Drug Discovery
Chih-Yuan Tseng
2014-07-01
Full Text Available Drug discovery applies multidisciplinary approaches either experimentally, computationally or both ways to identify lead compounds to treat various diseases. While conventional approaches have yielded many US Food and Drug Administration (FDA-approved drugs, researchers continue investigating and designing better approaches to increase the success rate in the discovery process. In this article, we provide an overview of the current strategies and point out where and how the method of maximum entropy has been introduced in this area. The maximum entropy principle has its root in thermodynamics, yet since Jaynes’ pioneering work in the 1950s, the maximum entropy principle has not only been used as a physics law, but also as a reasoning tool that allows us to process information in hand with the least bias. Its applicability in various disciplines has been abundantly demonstrated. We give several examples of applications of maximum entropy in different stages of drug discovery. Finally, we discuss a promising new direction in drug discovery that is likely to hinge on the ways of utilizing maximum entropy.
Back Work Ratio of Brayton Cycle
Malaver de la Fuente M.
2010-07-01
Full Text Available This paper analizes the existing relation between temperatures, back work ratio and net work of Brayton cycle, a cycle that describes gas turbine engines performance. The application of computational soft ware helps to show the influence of back work ratio or coupling ratio, compressor and turbine in let temperatures in an ideal thermodynamical cycle. The results lead to deduce that the maximum value reached in back work ratio will depend on the ranges of maximum and minimal temperatures of Brayton cycle.
Maximum Likelihood Analysis in the PEN Experiment
Lehman, Martin
2013-10-01
The experimental determination of the π+ -->e+ ν (γ) decay branching ratio currently provides the most accurate test of lepton universality. The PEN experiment at PSI, Switzerland, aims to improve the present world average experimental precision of 3 . 3 ×10-3 to 5 ×10-4 using a stopped beam approach. During runs in 2008-10, PEN has acquired over 2 ×107 πe 2 events. The experiment includes active beam detectors (degrader, mini TPC, target), central MWPC tracking with plastic scintillator hodoscopes, and a spherical pure CsI electromagnetic shower calorimeter. The final branching ratio will be calculated using a maximum likelihood analysis. This analysis assigns each event a probability for 5 processes (π+ -->e+ ν , π+ -->μ+ ν , decay-in-flight, pile-up, and hadronic events) using Monte Carlo verified probability distribution functions of our observables (energies, times, etc). A progress report on the PEN maximum likelihood analysis will be presented. Work supported by NSF grant PHY-0970013.
Greenslade, Thomas B., Jr.
1985-01-01
Discusses a series of experiments performed by Thomas Hope in 1805 which show the temperature at which water has its maximum density. Early data cast into a modern form as well as guidelines and recent data collected from the author provide background for duplicating Hope's experiments in the classroom. (JN)
Abolishing the maximum tension principle
Dabrowski, Mariusz P
2015-01-01
We find the series of example theories for which the relativistic limit of maximum tension $F_{max} = c^2/4G$ represented by the entropic force can be abolished. Among them the varying constants theories, some generalized entropy models applied both for cosmological and black hole horizons as well as some generalized uncertainty principle models.
Abolishing the maximum tension principle
Mariusz P. Da̧browski
2015-09-01
Full Text Available We find the series of example theories for which the relativistic limit of maximum tension Fmax=c4/4G represented by the entropic force can be abolished. Among them the varying constants theories, some generalized entropy models applied both for cosmological and black hole horizons as well as some generalized uncertainty principle models.
Phase contrast image synthesis
Glückstad, J.
1996-01-01
A new method is presented for synthesizing arbitrary intensity patterns based on phase contrast imaging. The concept is grounded on an extension of the Zernike phase contrast method into the domain of full range [0; 2 pi] phase modulation. By controlling the average value of the input phase...... function and by choosing appropriate phase retardation at the phase contrast filter, a pure phase to intensity imaging is accomplished. The method presented is also directly applicable in dark field image synthesis....
Stacul, Fulvio; van der Molen, Aart J; Reimer, Peter
2011-01-01
measures used to reduce the incidence of CIN, and the management of patients receiving metformin. Key Points • Definition, risk factors and prevention of contrast medium induced nephropathy are reviewed. • CIN risk is lower with intravenous than intra-arterial iodinated contrast medium. • eGFR of 45 ml....../min/1.73 m (2) is CIN risk threshold for intravenous contrast medium. • Hydration with either saline or sodium bicarbonate reduces CIN incidence. • Patients with eGFR ≥ 60 ml/min/1.73 m (2) receiving contrast medium can continue metformin normally....
Stacul, Fulvio; van der Molen, Aart J; Reimer, Peter
2011-01-01
measures used to reduce the incidence of CIN, and the management of patients receiving metformin. Key Points • Definition, risk factors and prevention of contrast medium induced nephropathy are reviewed. • CIN risk is lower with intravenous than intra-arterial iodinated contrast medium. • eGFR of 45 ml....../min/1.73 m (2) is CIN risk threshold for intravenous contrast medium. • Hydration with either saline or sodium bicarbonate reduces CIN incidence. • Patients with eGFR = 60 ml/min/1.73 m (2) receiving contrast medium can continue metformin normally....
Maximum Genus of Strong Embeddings
Er-ling Wei; Yan-pei Liu; Han Ren
2003-01-01
The strong embedding conjecture states that any 2-connected graph has a strong embedding on some surface. It implies the circuit double cover conjecture: Any 2-connected graph has a circuit double cover.Conversely, it is not true. But for a 3-regular graph, the two conjectures are equivalent. In this paper, a characterization of graphs having a strong embedding with exactly 3 faces, which is the strong embedding of maximum genus, is given. In addition, some graphs with the property are provided. More generally, an upper bound of the maximum genus of strong embeddings of a graph is presented too. Lastly, it is shown that the interpolation theorem is true to planar Halin graph.
Non-contrast-enhanced peripheral MR angiography using velocity-selective excitation.
Kim, Dongchan; Seo, Hyunseok; Cho, Jaejin; Kwon, Kinam; Han, Yeji; Park, HyunWook
2017-06-05
To develop a new non-contrast-enhanced peripheral MR angiography that provides a high contrast angiogram without using electrocardiography triggering and saturation radiofrequency pulses. A velocity-selective excitation technique is used in conjunction with the golden-angle radial sampling scheme. The signal amplitude varies according to the velocity of the flow by the velocity-selective excitation technique. Because the arterial blood velocity varies depending on the cardiac phase, the acquired data can be classified into systolic and diastolic phase based on the signal amplitude of the artery. Two images are then reconstructed from the systolic and diastolic phase data, respectively, and an image reflecting the differences between the two images is obtained to eliminate background and vein signals. The performance of the proposed method was compared with the quiescent-interval single shot (QISS) in eight healthy subjects and an elderly subject. The proposed method generated fewer residual venous and background signals than the QISS. Furthermore, the maximum intensity projection images, the relative contrast, and the apparent contrast-to-noise ratio results showed that the proposed method produced a better contrast than the QISS. The proposed non-contrast-enhanced peripheral MR angiography technique can provide a high contrast angiogram without the use of electrocardiography triggering and saturation radiofrequency pulses. Magn Reson Med, 2017. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.
Estruturas silicosas na gramínea Panicum maximum
Pedro Fontana Junior
1957-05-01
Full Text Available The silica structure of the grass Panicum maximum were studied by electron and phase contrast microscopy. Several interesting kinds of silica formation (spiklets were found. The most ineresting structures ressembels the "Schaumstruktur" found by HELMCKE in diatoms. Another interesting structure was described in the "silica cells" and a detailed study of the mophology of some different kinds of spiklets was made.
Remizov, Ivan D
2009-01-01
In this note, we represent a subdifferential of a maximum functional defined on the space of all real-valued continuous functions on a given metric compact set. For a given argument, $f$ it coincides with the set of all probability measures on the set of points maximizing $f$ on the initial compact set. This complete characterization lies in the heart of several important identities in microeconomics, such as Roy's identity, Sheppard's lemma, as well as duality theory in production and linear programming.
Radionuclide tumor therapy with ultrasound contrast microbubbles
Wamel, van Annemieke; Bouakaz, Ayache; Bernard, Bert; Cate, ten Folkert; Jong, de Nico
2004-01-01
Radionuclides have shown to be effective in tumour therapy. However, the side effects determine the maximum deliverable dose. Recently, it has been demonstrated that cells can be permeabilised through sonoporation using ultrasound and contrast microbubbles. The use of sonoporation in treatment of tu
Iterative Reconstruction for Differential Phase Contrast Imaging
Koehler, T.; Brendel, B.; Roessl, E.
2011-01-01
Purpose: The purpose of this work is to combine two areas of active research in tomographic x-ray imaging. The first one is the use of iterative reconstruction techniques. The second one is differential phase contrast imaging (DPCI). Method: We derive an SPS type maximum likelihood (ML) reconstructi
The Testability of Maximum Magnitude
Clements, R.; Schorlemmer, D.; Gonzalez, A.; Zoeller, G.; Schneider, M.
2012-12-01
Recent disasters caused by earthquakes of unexpectedly large magnitude (such as Tohoku) illustrate the need for reliable assessments of the seismic hazard. Estimates of the maximum possible magnitude M at a given fault or in a particular zone are essential parameters in probabilistic seismic hazard assessment (PSHA), but their accuracy remains untested. In this study, we discuss the testability of long-term and short-term M estimates and the limitations that arise from testing such rare events. Of considerable importance is whether or not those limitations imply a lack of testability of a useful maximum magnitude estimate, and whether this should have any influence on current PSHA methodology. We use a simple extreme value theory approach to derive a probability distribution for the expected maximum magnitude in a future time interval, and we perform a sensitivity analysis on this distribution to determine if there is a reasonable avenue available for testing M estimates as they are commonly reported today: devoid of an appropriate probability distribution of their own and estimated only for infinite time (or relatively large untestable periods). Our results imply that any attempt at testing such estimates is futile, and that the distribution is highly sensitive to M estimates only under certain optimal conditions that are rarely observed in practice. In the future we suggest that PSHA modelers be brutally honest about the uncertainty of M estimates, or must find a way to decrease its influence on the estimated hazard.
Alternative Multiview Maximum Entropy Discrimination.
Chao, Guoqing; Sun, Shiliang
2016-07-01
Maximum entropy discrimination (MED) is a general framework for discriminative estimation based on maximum entropy and maximum margin principles, and can produce hard-margin support vector machines under some assumptions. Recently, the multiview version of MED multiview MED (MVMED) was proposed. In this paper, we try to explore a more natural MVMED framework by assuming two separate distributions p1( Θ1) over the first-view classifier parameter Θ1 and p2( Θ2) over the second-view classifier parameter Θ2 . We name the new MVMED framework as alternative MVMED (AMVMED), which enforces the posteriors of two view margins to be equal. The proposed AMVMED is more flexible than the existing MVMED, because compared with MVMED, which optimizes one relative entropy, AMVMED assigns one relative entropy term to each of the two views, thus incorporating a tradeoff between the two views. We give the detailed solving procedure, which can be divided into two steps. The first step is solving our optimization problem without considering the equal margin posteriors from two views, and then, in the second step, we consider the equal posteriors. Experimental results on multiple real-world data sets verify the effectiveness of the AMVMED, and comparisons with MVMED are also reported.
Sonophoresis Using Ultrasound Contrast Agents: Dependence on Concentration.
Donghee Park
Full Text Available Sonophoresis can increase skin permeability to various drugs in transdermal drug delivery. Cavitation is recognized as the predominant mechanism of sonophoresis. Recently, a new logical approach to enhance the efficiency of transdermal drug delivery was tried. It is to utilize the engineered microbubble and its resonant frequency for increase of cavitation activity. Actively-induced cavitation with low-intensity ultrasound (less than ~1 MPa causes disordering of the lipid bilayers and the formation of aqueous channels by stable cavitation which indicates a continuous oscillation of bubbles. Furthermore, the mutual interactions of microbubble determined by concentration of added bubble are also thought to be an important factor for activity of stable cavitation, even in different characteristics of drug. In the present study, we addressed the dependence of ultrasound contrast agent concentration using two types of drug on the efficiency of transdermal drug delivery. Two types of experiment were designed to quantitatively evaluate the efficiency of transdermal drug delivery according to ultrasound contrast agent concentration. First, an experiment of optical clearing using a tissue optical clearing agent was designed to assess the efficiency of sonophoresis with ultrasound contrast agents. Second, a Franz diffusion cell with ferulic acid was used to quantitatively determine the amount of drug delivered to the skin sample by sonophoresis with ultrasound contrast agents. The maximum enhancement ratio of sonophoresis with a concentration of 1:1,000 was approximately 3.1 times greater than that in the ultrasound group without ultrasound contrast agent and approximately 7.5 times greater than that in the control group. These results support our hypothesis that sonophoresis becomes more effective in transdermal drug delivery due to the presence of engineered bubbles, and that the efficiency of transdermal drug delivery using sonophoresis with
Cacti with maximum Kirchhoff index
Wang, Wen-Rui; Pan, Xiang-Feng
2015-01-01
The concept of resistance distance was first proposed by Klein and Randi\\'c. The Kirchhoff index $Kf(G)$ of a graph $G$ is the sum of resistance distance between all pairs of vertices in $G$. A connected graph $G$ is called a cactus if each block of $G$ is either an edge or a cycle. Let $Cat(n;t)$ be the set of connected cacti possessing $n$ vertices and $t$ cycles, where $0\\leq t \\leq \\lfloor\\frac{n-1}{2}\\rfloor$. In this paper, the maximum kirchhoff index of cacti are characterized, as well...
Generic maximum likely scale selection
Pedersen, Kim Steenstrup; Loog, Marco; Markussen, Bo
2007-01-01
The fundamental problem of local scale selection is addressed by means of a novel principle, which is based on maximum likelihood estimation. The principle is generally applicable to a broad variety of image models and descriptors, and provides a generic scale estimation methodology. The focus...... on second order moments of multiple measurements outputs at a fixed location. These measurements, which reflect local image structure, consist in the cases considered here of Gaussian derivatives taken at several scales and/or having different derivative orders....
Economics and Maximum Entropy Production
Lorenz, R. D.
2003-04-01
Price differentials, sales volume and profit can be seen as analogues of temperature difference, heat flow and work or entropy production in the climate system. One aspect in which economic systems exhibit more clarity than the climate is that the empirical and/or statistical mechanical tendency for systems to seek a maximum in production is very evident in economics, in that the profit motive is very clear. Noting the common link between 1/f noise, power laws and Self-Organized Criticality with Maximum Entropy Production, the power law fluctuations in security and commodity prices is not inconsistent with the analogy. There is an additional thermodynamic analogy, in that scarcity is valued. A commodity concentrated among a few traders is valued highly by the many who do not have it. The market therefore encourages via prices the spreading of those goods among a wider group, just as heat tends to diffuse, increasing entropy. I explore some empirical price-volume relationships of metals and meteorites in this context.
Describing contrast across scales
Syed, Sohaib Ali; Iqbal, Muhammad Zafar; Riaz, Muhammad Mohsin
2017-06-01
Due to its sensitive nature against illumination and noise distributions, contrast is not widely used for image description. On the contrary, the human perception of contrast along different spatial frequency bandwidths provides a powerful discriminator function that can be modeled in a robust manner against local illumination. Based upon this observation, a dense local contrast descriptor is proposed and its potential in different applications of computer vision is discussed. Extensive experiments reveal that this simple yet effective description performs well in comparison with state of the art image descriptors. We also show the importance of this description in multiresolution pansharpening framework.
Birzvalk, Yu.
1978-01-01
The shunting ratio and the local shunting ratio, pertaining to currents induced by a magnetic field in a flow channel, are properly defined and systematically reviewed on the basis of the Lagrange criterion. Their definition is based on the energy balance and related to dimensionless parameters characterizing an MHD flow, these parameters evolving from the Hartmann number and the hydrodynamic Reynolds number as well as the magnetic Reynolds number, and the Lundquist number. These shunting ratios, of current density in the core of a stream (uniform) or equivalent mean current density to the short-circuit (maximum) current density, are given here for a slot channel with nonconducting or conducting walls, for a conduction channel with heavy side rails, and for an MHD-flow around bodies. 5 references, 1 figure.
Glückstad, Jesper; Palima, Darwin
Generalized Phase Contrast elevates the phase contrast technique not only to improve phase imaging but also to cross over and interface with diverse and seemingly disparate fields of contemporary optics and photonics. This book presents a comprehensive introduction to the Generalized Phase Contrast...... (GPC) method including an overview of the range of current and potential applications of GPC in wavefront sensing and phase imaging, structured laser illumination and image projection, optical trapping and manipulation, and optical encryption and decryption. The GPC method goes further than...... efficiency. Optimization can address practical issues, such as finding an optimal spatial filter for the chosen application, and can even enable a Reverse Phase Contrast mode where intensity patterns are converted into a phase modulation....
Glückstad, Jesper
2009-01-01
Generalized Phase Contrast elevates the phase contrast technique not only to improve phase imaging but also to cross over and interface with diverse and seemingly disparate fields of contemporary optics and photonics. This book presents a comprehensive introduction to the Generalized Phase Contrast (GPC) method including an overview of the range of current and potential applications of GPC in wavefront sensing and phase imaging, structured laser illumination and image projection, optical trapping and manipulation, and optical encryption and decryption. The GPC method goes further than the restrictive assumptions of conventional Zernike phase contrast analysis and achieves an expanded range of validity beyond weak phase perturbations. The generalized analysis yields design criteria for tuning experimental parameters to achieve optimal performance in terms of accuracy, fidelity and light efficiency. Optimization can address practical issues, such as finding an optimal spatial filter for the chosen application, ...
Glückstad, Jesper; Palima, Darwin
Generalized Phase Contrast elevates the phase contrast technique not only to improve phase imaging but also to cross over and interface with diverse and seemingly disparate fields of contemporary optics and photonics. This book presents a comprehensive introduction to the Generalized Phase Contrast...... (GPC) method including an overview of the range of current and potential applications of GPC in wavefront sensing and phase imaging, structured laser illumination and image projection, optical trapping and manipulation, and optical encryption and decryption. The GPC method goes further than...... the restrictive assumptions of conventional Zernike phase contrast analysis and achieves an expanded range of validity beyond weak phase perturbations. The generalized analysis yields design criteria for tuning experimental parameters to achieve optimal performance in terms of accuracy, fidelity and light...
Objects of maximum electromagnetic chirality
Fernandez-Corbaton, Ivan
2015-01-01
We introduce a definition of the electromagnetic chirality of an object and show that it has an upper bound. The upper bound is attained if and only if the object is transparent for fields of one handedness (helicity). Additionally, electromagnetic duality symmetry, i.e. helicity preservation upon scattering, turns out to be a necessary condition for reciprocal scatterers to attain the upper bound. We use these results to provide requirements for the design of such extremal scatterers. The requirements can be formulated as constraints on the polarizability tensors for dipolar scatterers or as material constitutive relations. We also outline two applications for objects of maximum electromagnetic chirality: A twofold resonantly enhanced and background free circular dichroism measurement setup, and angle independent helicity filtering glasses.
Maximum mutual information regularized classification
Wang, Jim Jing-Yan
2014-09-07
In this paper, a novel pattern classification approach is proposed by regularizing the classifier learning to maximize mutual information between the classification response and the true class label. We argue that, with the learned classifier, the uncertainty of the true class label of a data sample should be reduced by knowing its classification response as much as possible. The reduced uncertainty is measured by the mutual information between the classification response and the true class label. To this end, when learning a linear classifier, we propose to maximize the mutual information between classification responses and true class labels of training samples, besides minimizing the classification error and reducing the classifier complexity. An objective function is constructed by modeling mutual information with entropy estimation, and it is optimized by a gradient descend method in an iterative algorithm. Experiments on two real world pattern classification problems show the significant improvements achieved by maximum mutual information regularization.
The strong maximum principle revisited
Pucci, Patrizia; Serrin, James
In this paper we first present the classical maximum principle due to E. Hopf, together with an extended commentary and discussion of Hopf's paper. We emphasize the comparison technique invented by Hopf to prove this principle, which has since become a main mathematical tool for the study of second order elliptic partial differential equations and has generated an enormous number of important applications. While Hopf's principle is generally understood to apply to linear equations, it is in fact also crucial in nonlinear theories, such as those under consideration here. In particular, we shall treat and discuss recent generalizations of the strong maximum principle, and also the compact support principle, for the case of singular quasilinear elliptic differential inequalities, under generally weak assumptions on the quasilinear operators and the nonlinearities involved. Our principal interest is in necessary and sufficient conditions for the validity of both principles; in exposing and simplifying earlier proofs of corresponding results; and in extending the conclusions to wider classes of singular operators than previously considered. The results have unexpected ramifications for other problems, as will develop from the exposition, e.g. two point boundary value problems for singular quasilinear ordinary differential equations (Sections 3 and 4); the exterior Dirichlet boundary value problem (Section 5); the existence of dead cores and compact support solutions, i.e. dead cores at infinity (Section 7); Euler-Lagrange inequalities on a Riemannian manifold (Section 9); comparison and uniqueness theorems for solutions of singular quasilinear differential inequalities (Section 10). The case of p-regular elliptic inequalities is briefly considered in Section 11.
Theoretical Estimate of Maximum Possible Nuclear Explosion
Bethe, H. A.
1950-01-31
The maximum nuclear accident which could occur in a Na-cooled, Be moderated, Pu and power producing reactor is estimated theoretically. (T.R.H.) 2O82 Results of nuclear calculations for a variety of compositions of fast, heterogeneous, sodium-cooled, U-235-fueled, plutonium- and power-producing reactors are reported. Core compositions typical of plate-, pin-, or wire-type fuel elements and with uranium as metal, alloy, and oxide were considered. These compositions included atom ratios in the following range: U-23B to U-235 from 2 to 8; sodium to U-235 from 1.5 to 12; iron to U-235 from 5 to 18; and vanadium to U-235 from 11 to 33. Calculations were performed to determine the effect of lead and iron reflectors between the core and blanket. Both natural and depleted uranium were evaluated as the blanket fertile material. Reactors were compared on a basis of conversion ratio, specific power, and the product of both. The calculated results are in general agreement with the experimental results from fast reactor assemblies. An analysis of the effect of new cross-section values as they became available is included. (auth)
Maximum life spiral bevel reduction design
Savage, M.; Prasanna, M. G.; Coe, H. H.
1992-07-01
Optimization is applied to the design of a spiral bevel gear reduction for maximum life at a given size. A modified feasible directions search algorithm permits a wide variety of inequality constraints and exact design requirements to be met with low sensitivity to initial values. Gear tooth bending strength and minimum contact ratio under load are included in the active constraints. The optimal design of the spiral bevel gear reduction includes the selection of bearing and shaft proportions in addition to gear mesh parameters. System life is maximized subject to a fixed back-cone distance of the spiral bevel gear set for a specified speed ratio, shaft angle, input torque, and power. Significant parameters in the design are: the spiral angle, the pressure angle, the numbers of teeth on the pinion and gear, and the location and size of the four support bearings. Interpolated polynomials expand the discrete bearing properties and proportions into continuous variables for gradient optimization. After finding the continuous optimum, a designer can analyze near optimal designs for comparison and selection. Design examples show the influence of the bearing lives on the gear parameters in the optimal configurations. For a fixed back-cone distance, optimal designs with larger shaft angles have larger service lives.
Minimum length-maximum velocity
Panes, Boris
2012-03-01
We study a framework where the hypothesis of a minimum length in space-time is complemented with the notion of reference frame invariance. It turns out natural to interpret the action of the obtained reference frame transformations in the context of doubly special relativity. As a consequence of this formalism we find interesting connections between the minimum length properties and the modified velocity-energy relation for ultra-relativistic particles. For example, we can predict the ratio between the minimum lengths in space and time using the results from OPERA on superluminal neutrinos.
Maximum likelihood molecular clock comb: analytic solutions.
Chor, Benny; Khetan, Amit; Snir, Sagi
2006-04-01
Maximum likelihood (ML) is increasingly used as an optimality criterion for selecting evolutionary trees, but finding the global optimum is a hard computational task. Because no general analytic solution is known, numeric techniques such as hill climbing or expectation maximization (EM), are used in order to find optimal parameters for a given tree. So far, analytic solutions were derived only for the simplest model--three taxa, two state characters, under a molecular clock. Four taxa rooted trees have two topologies--the fork (two subtrees with two leaves each) and the comb (one subtree with three leaves, the other with a single leaf). In a previous work, we devised a closed form analytic solution for the ML molecular clock fork. In this work, we extend the state of the art in the area of analytic solutions ML trees to the family of all four taxa trees under the molecular clock assumption. The change from the fork topology to the comb incurs a major increase in the complexity of the underlying algebraic system and requires novel techniques and approaches. We combine the ultrametric properties of molecular clock trees with the Hadamard conjugation to derive a number of topology dependent identities. Employing these identities, we substantially simplify the system of polynomial equations. We finally use tools from algebraic geometry (e.g., Gröbner bases, ideal saturation, resultants) and employ symbolic algebra software to obtain analytic solutions for the comb. We show that in contrast to the fork, the comb has no closed form solutions (expressed by radicals in the input data). In general, four taxa trees can have multiple ML points. In contrast, we can now prove that under the molecular clock assumption, the comb has a unique (local and global) ML point. (Such uniqueness was previously shown for the fork.).
Anisotropic Contrast Optical Microscope
Peev, D; Kananizadeh, N; Wimer, S; Rodenhausen, K B; Herzinger, C M; Kasputis, T; Pfaunmiller, E; Nguyen, A; Korlacki, R; Pannier, A; Li, Y; Schubert, E; Hage, D; Schubert, M
2016-01-01
An optical microscope is described that reveals contrast in the Mueller matrix images of a thin, transparent or semi-transparent specimen located within an anisotropic object plane (anisotropic filter). The specimen changes the anisotropy of the filter and thereby produces contrast within the Mueller matrix images. Here we use an anisotropic filter composed of a semi-transparent, nanostructured thin film with sub-wavelength thickness placed within the object plane. The sample is illuminated as in common optical microscopy but the light is modulated in its polarization using combinations of linear polarizers and phase plate (compensator) to control and analyze the state of polarization. Direct generalized ellipsometry data analysis approaches permit extraction of fundamental Mueller matrix object plane images dispensing with the need of Fourier expansion methods. Generalized ellipsometry model approaches are used for quantitative image analyses. We demonstrate the anisotropic contrast optical microscope by mea...
Maximum entropy production in daisyworld
Maunu, Haley A.; Knuth, Kevin H.
2012-05-01
Daisyworld was first introduced in 1983 by Watson and Lovelock as a model that illustrates how life can influence a planet's climate. These models typically involve modeling a planetary surface on which black and white daisies can grow thus influencing the local surface albedo and therefore also the temperature distribution. Since then, variations of daisyworld have been applied to study problems ranging from ecological systems to global climate. Much of the interest in daisyworld models is due to the fact that they enable one to study self-regulating systems. These models are nonlinear, and as such they exhibit sensitive dependence on initial conditions, and depending on the specifics of the model they can also exhibit feedback loops, oscillations, and chaotic behavior. Many daisyworld models are thermodynamic in nature in that they rely on heat flux and temperature gradients. However, what is not well-known is whether, or even why, a daisyworld model might settle into a maximum entropy production (MEP) state. With the aim to better understand these systems, this paper will discuss what is known about the role of MEP in daisyworld models.
Maximum stellar iron core mass
F W Giacobbe
2003-03-01
An analytical method of estimating the mass of a stellar iron core, just prior to core collapse, is described in this paper. The method employed depends, in part, upon an estimate of the true relativistic mass increase experienced by electrons within a highly compressed iron core, just prior to core collapse, and is signiﬁcantly different from a more typical Chandrasekhar mass limit approach. This technique produced a maximum stellar iron core mass value of 2.69 × 1030 kg (1.35 solar masses). This mass value is very near to the typical mass values found for neutron stars in a recent survey of actual neutron star masses. Although slightly lower and higher neutron star masses may also be found, lower mass neutron stars are believed to be formed as a result of enhanced iron core compression due to the weight of non-ferrous matter overlying the iron cores within large stars. And, higher mass neutron stars are likely to be formed as a result of fallback or accretion of additional matter after an initial collapse event involving an iron core having a mass no greater than 2.69 × 1030 kg.
Maximum Matchings via Glauber Dynamics
Jindal, Anant; Pal, Manjish
2011-01-01
In this paper we study the classic problem of computing a maximum cardinality matching in general graphs $G = (V, E)$. The best known algorithm for this problem till date runs in $O(m \\sqrt{n})$ time due to Micali and Vazirani \\cite{MV80}. Even for general bipartite graphs this is the best known running time (the algorithm of Karp and Hopcroft \\cite{HK73} also achieves this bound). For regular bipartite graphs one can achieve an $O(m)$ time algorithm which, following a series of papers, has been recently improved to $O(n \\log n)$ by Goel, Kapralov and Khanna (STOC 2010) \\cite{GKK10}. In this paper we present a randomized algorithm based on the Markov Chain Monte Carlo paradigm which runs in $O(m \\log^2 n)$ time, thereby obtaining a significant improvement over \\cite{MV80}. We use a Markov chain similar to the \\emph{hard-core model} for Glauber Dynamics with \\emph{fugacity} parameter $\\lambda$, which is used to sample independent sets in a graph from the Gibbs Distribution \\cite{V99}, to design a faster algori...
2011-01-10
...: Establishing Maximum Allowable Operating Pressure or Maximum Operating Pressure Using Record Evidence, and... facilities of their responsibilities, under Federal integrity management (IM) regulations, to perform... system, especially when calculating Maximum Allowable Operating Pressure (MAOP) or Maximum Operating...
A Family of Maximum SNR Filters for Noise Reduction
Huang, Gongping; Benesty, Jacob; Long, Tao;
2014-01-01
This paper is devoted to the study and analysis of the maximum signal-to-noise ratio (SNR) filters for noise reduction both in the time and short-time Fourier transform (STFT) domains with one single microphone and multiple microphones. In the time domain, we show that the maximum SNR filters can...... significantly increase the SNR but at the expense of tremendous speech distortion. As a consequence, the speech quality improvement, measured by the perceptual evaluation of speech quality (PESQ) algorithm, is marginal if any, regardless of the number of microphones used. In the STFT domain, the maximum SNR....... This demonstrates that the maximum SNR filters, particularly the multichannel ones, in the STFT domain may be of great practical value....
Compressive Phase Contrast Tomography
Maia, F R N C; Marchesini, S; Padmore, H A; Parkinson, D Y; Pien, J; Schirotzek, A; Yang, C; 10.1117/12.861946
2010-01-01
When x-rays penetrate soft matter, their phase changes more rapidly than their amplitude. In- terference effects visible with high brightness sources creates higher contrast, edge enhanced images. When the object is piecewise smooth (made of big blocks of a few components), such higher con- trast datasets have a sparse solution. We apply basis pursuit solvers to improve SNR, remove ring artifacts, reduce the number of views and radiation dose from phase contrast datasets collected at the Hard X-Ray Micro Tomography Beamline at the Advanced Light Source. We report a GPU code for the most computationally intensive task, the gridding and inverse gridding algorithm (non uniform sampled Fourier transform).
The Sherpa Maximum Likelihood Estimator
Nguyen, D.; Doe, S.; Evans, I.; Hain, R.; Primini, F.
2011-07-01
A primary goal for the second release of the Chandra Source Catalog (CSC) is to include X-ray sources with as few as 5 photon counts detected in stacked observations of the same field, while maintaining acceptable detection efficiency and false source rates. Aggressive source detection methods will result in detection of many false positive source candidates. Candidate detections will then be sent to a new tool, the Maximum Likelihood Estimator (MLE), to evaluate the likelihood that a detection is a real source. MLE uses the Sherpa modeling and fitting engine to fit a model of a background and source to multiple overlapping candidate source regions. A background model is calculated by simultaneously fitting the observed photon flux in multiple background regions. This model is used to determine the quality of the fit statistic for a background-only hypothesis in the potential source region. The statistic for a background-plus-source hypothesis is calculated by adding a Gaussian source model convolved with the appropriate Chandra point spread function (PSF) and simultaneously fitting the observed photon flux in each observation in the stack. Since a candidate source may be located anywhere in the field of view of each stacked observation, a different PSF must be used for each observation because of the strong spatial dependence of the Chandra PSF. The likelihood of a valid source being detected is a function of the two statistics (for background alone, and for background-plus-source). The MLE tool is an extensible Python module with potential for use by the general Chandra user.
Spectral ratio method for measuring emissivity
Watson, K.
1992-01-01
The spectral ratio method is based on the concept that although the spectral radiances are very sensitive to small changes in temperature the ratios are not. Only an approximate estimate of temperature is required thus, for example, we can determine the emissivity ratio to an accuracy of 1% with a temperature estimate that is only accurate to 12.5 K. Selecting the maximum value of the channel brightness temperatures is an unbiased estimate. Laboratory and field spectral data are easily converted into spectral ratio plots. The ratio method is limited by system signal:noise and spectral band-width. The images can appear quite noisy because ratios enhance high frequencies and may require spatial filtering. Atmospheric effects tend to rescale the ratios and require using an atmospheric model or a calibration site. ?? 1992.
Kalle, Thekla von; Stuber, Tina; Winkler, Peter [Olgahospital Klinikum Stuttgart, Pediatric Radiology, Radiologisches Institut, Stuttgart (Germany); Maier, Jan; Hospach, Toni [Olgahospital Klinikum Stuttgart, Pediatric Rheumatology, Stuttgart (Germany)
2015-03-01
Early treatment of temporomandibular joint (TMJ) arthritis is crucial in children with juvenile idiopathic arthritis (JIA) to prevent permanent functional impairment. As involvement of TMJs is often asymptomatic, contrast-enhanced MRI is regarded as the most sensitive noninvasive diagnostic tool. To evaluate the degree of contrast enhancement in TMJs of children and adolescents with JIA in comparison to normal controls from a previous study. Dynamic contrast-enhanced MRI of 50 children and adolescents with JIA (6.3 to 18 years of age; mean: 12 years) were retrospectively analysed. We assessed morphological abnormalities and postcontrast time-intensity curves of the soft joint tissue and the mandibular condyle. Ratios were calculated to quantify postcontrast signal intensities (SI) in relation to precontrast SI at initial (1 min postcontrast) and maximum (6 min postcontrast) increase. Time-intensity curves followed similar biphasic patterns in normal and pathological joints. In joints with morphological signs of arthritis, mean SI ratios were on average higher than in normal joints of the reference group, but ranges of values widely overlapped. Arthritis: mean initial increase of SI 62% (±2 S.D. 18-105%), mean maximum SI 106% higher than precontrast (±2 S.D. 46-166%). Normal: mean initial increase of SI 49% (±2 S.D. 14- 85%), mean maximum of SI 73% (±2 S.D. 23-123%). Given this considerable overlap of results in dynamic contrast-enhanced MRI, the degree of contrast enhancement alone did not allow differentiation between TMJs with and without signs of inflammation. Thickening of the soft joint tissue seems to remain the earliest sign to reliably indicate TMJ arthritis. (orig.)
Proscriptive Bayesian Programming and Maximum Entropy: a Preliminary Study
Koike, Carla Cavalcante
2008-11-01
Some problems found in robotics systems, as avoiding obstacles, can be better described using proscriptive commands, where only prohibited actions are indicated in contrast to prescriptive situations, which demands that a specific command be specified. An interesting question arises regarding the possibility to learn automatically if proscriptive commands are suitable and which parametric function could be better applied. Lately, a great variety of problems in robotics domain are object of researches using probabilistic methods, including the use of Maximum Entropy in automatic learning for robot control systems. This works presents a preliminary study on automatic learning of proscriptive robot control using maximum entropy and using Bayesian Programming. It is verified whether Maximum entropy and related methods can favour proscriptive commands in an obstacle avoidance task executed by a mobile robot.
Semidefinite Programming for Approximate Maximum Likelihood Sinusoidal Parameter Estimation
Kenneth W. K. Lui
2009-01-01
Full Text Available We study the convex optimization approach for parameter estimation of several sinusoidal models, namely, single complex/real tone, multiple complex sinusoids, and single two-dimensional complex tone, in the presence of additive Gaussian noise. The major difficulty for optimally determining the parameters is that the corresponding maximum likelihood (ML estimators involve finding the global minimum or maximum of multimodal cost functions because the frequencies are nonlinear in the observed signals. By relaxing the nonconvex ML formulations using semidefinite programs, high-fidelity approximate solutions are obtained in a globally optimum fashion. Computer simulations are included to contrast the estimation performance of the proposed semi-definite relaxation methods with the iterative quadratic maximum likelihood technique as well as Cramér-Rao lower bound.
Semidefinite Programming for Approximate Maximum Likelihood Sinusoidal Parameter Estimation
Lui, Kenneth W. K.; So, H. C.
2009-12-01
We study the convex optimization approach for parameter estimation of several sinusoidal models, namely, single complex/real tone, multiple complex sinusoids, and single two-dimensional complex tone, in the presence of additive Gaussian noise. The major difficulty for optimally determining the parameters is that the corresponding maximum likelihood (ML) estimators involve finding the global minimum or maximum of multimodal cost functions because the frequencies are nonlinear in the observed signals. By relaxing the nonconvex ML formulations using semidefinite programs, high-fidelity approximate solutions are obtained in a globally optimum fashion. Computer simulations are included to contrast the estimation performance of the proposed semi-definite relaxation methods with the iterative quadratic maximum likelihood technique as well as Cramér-Rao lower bound.
High-contrast top-emitting organic light-emitting devices
Chen Shu-Fen; Chen Chun-Yan; Yang Yang; Xie Jun; Huang Wei; Shi Hong-Ying; Cheng Fan
2012-01-01
In this paper we report on a high-contrast top-emitting organic light-emitting device utilizing a moderate-reflection contrast-enhancement stack and a high refractive index anti-reflection layer.The contrast-enhancement stack consists of a thin metal anode layer,a dielectric bilayer,and a thick metal underlayer.The resulting device,with the optimized contrast-enhancement stack thicknesses of Ni (30 nm)/MgF2 (62 nm)/ZnS (16 nm)/Ni (20 nm) and the 25-nm-thick ZnS anti-reflection layer,achieves a luminous reflectance of 4.01％ in the visible region and a maximum current efficiency of 0.99 cd/A (at 62.3 mA/cm2) together with a very stable chromaticity.The contrast ratio reaches 561∶1 at an on-state brightness of 1000 cd/m2 under an ambient illumination of 140 lx.In addition,the anti-reflection layer can als0 enhance the transmissivity of the cathode and improve light out-coupling by the effective restraint of microcavity effects.
Polychromatic diffraction contrast tomography
King, A., E-mail: king@synchrotron-soleil.fr [Synchrotron SOLEIL, Gif-sur-Yvette 91192 (France); Reischig, P. [Xnovo Technology ApS, 4600 Køge (Denmark); Department of Materials Science and Engineering, Delft University of Technology, Delft 2628 CD (Netherlands); Adrien, J. [MATEIS, INSA de Lyon, Villeurbanne 69621 (France); Peetermans, S. [Paul Scherrer Institut, CH-5232 Villigen (Switzerland); Ludwig, W. [MATEIS, INSA de Lyon, Villeurbanne 69621 (France); European Synchrotron Radiation Facility, Grenoble 38043 (France)
2014-11-15
This tutorial review introduces the use of polychromatic radiation for 3D grain mapping using X-ray diffraction contrast tomography. The objective is to produce a 3D map of the grain shapes and orientations within a bulk, millimeter-sized polycrystalline sample. The use of polychromatic radiation enables the standard synchrotron X-ray technique to be applied in a wider range of contexts: 1) Using laboratory X-ray sources allows a much wider application of the diffraction contrast tomography technique. 2) Neutron sources allow large samples, or samples containing high Z elements to be studied. 3) Applied to synchrotron sources, smaller samples may be treated, or faster measurements may be possible. Challenges and particularities in the data acquisition and processing, and the limitations of the different variants, are discussed. - Highlights: • We present a tutorial review of polychromatic diffraction contrast tomography techniques. • The use of polychromatic radiation allows the standard synchrotron DCT technique to be extended to a range of other sources. • The characteristics and limitations of all variants of the techniques are derived, discussed and compared. • Examples using laboratory X-ray and cold neutron radiation are presented. • Suggestions for the future development of these techniques are presented.
Michael Wagner
2012-12-01
Full Text Available The analysis of contrastive topics introduced in Büring 1997b and further developed in Büring 2003 relies on distinguishing two types of constituents that introduce alternatives: the sentence focus, which is marked by a FOC feature, and the contrastive topic, which is marked by a CT feature. A non-compositional rule of interpretation that refers to these features is used to derive a topic semantic value, a nested set of sets of propositions. This paper presents evidence for a correlation between the restrictive syntax of nested focus operators and the syntax of contrastive topics, a correlation which is unexpected under this analysis. A compositional analysis is proposed that only makes use of the flatter focus semantic values introduced by focus operators. The analysis aims at integrating insights from the original analysis while at the same time capturing the observed syntactic restrictions. http://dx.doi.org/10.3765/sp.5.8 BibTeX info
From Fibonacci Sequence to the Golden Ratio
Alberto Fiorenza
2013-01-01
Full Text Available We consider the well-known characterization of the Golden ratio as limit of the ratio of consecutive terms of the Fibonacci sequence, and we give an explanation of this property in the framework of the Difference Equations Theory. We show that the Golden ratio coincides with this limit not because it is the root with maximum modulus and multiplicity of the characteristic polynomial, but, from a more general point of view, because it is the root with maximum modulus and multiplicity of a restricted set of roots, which in this special case coincides with the two roots of the characteristic polynomial. This new perspective is the heart of the characterization of the limit of ratio of consecutive terms of all linear homogeneous recurrences with constant coefficients, without any assumption on the roots of the characteristic polynomial, which may be, in particular, also complex and not real.
Anisotropic contrast optical microscope
Peev, D.; Hofmann, T.; Kananizadeh, N.; Beeram, S.; Rodriguez, E.; Wimer, S.; Rodenhausen, K. B.; Herzinger, C. M.; Kasputis, T.; Pfaunmiller, E.; Nguyen, A.; Korlacki, R.; Pannier, A.; Li, Y.; Schubert, E.; Hage, D.; Schubert, M.
2016-11-01
An optical microscope is described that reveals contrast in the Mueller matrix images of a thin, transparent, or semi-transparent specimen located within an anisotropic object plane (anisotropic filter). The specimen changes the anisotropy of the filter and thereby produces contrast within the Mueller matrix images. Here we use an anisotropic filter composed of a semi-transparent, nanostructured thin film with sub-wavelength thickness placed within the object plane. The sample is illuminated as in common optical microscopy but the light is modulated in its polarization using combinations of linear polarizers and phase plate (compensator) to control and analyze the state of polarization. Direct generalized ellipsometry data analysis approaches permit extraction of fundamental Mueller matrix object plane images dispensing with the need of Fourier expansion methods. Generalized ellipsometry model approaches are used for quantitative image analyses. These images are obtained from sets of multiple images obtained under various polarizer, analyzer, and compensator settings. Up to 16 independent Mueller matrix images can be obtained, while our current setup is limited to 11 images normalized by the unpolarized intensity. We demonstrate the anisotropic contrast optical microscope by measuring lithographically defined micro-patterned anisotropic filters, and we quantify the adsorption of an organic self-assembled monolayer film onto the anisotropic filter. Comparison with an isotropic glass slide demonstrates the image enhancement obtained by our method over microscopy without the use of an anisotropic filter. In our current instrument, we estimate the limit of detection for organic volumetric mass within the object plane of ≈49 fg within ≈7 × 7 μm2 object surface area. Compared to a quartz crystal microbalance with dissipation instrumentation, where contemporary limits require a total load of ≈500 pg for detection, the instrumentation demonstrated here improves
Beam Space Formulation of the Maximum Signal-to-Noise Ratio Array Processor.
1980-12-01
To investigate the dependance of the beam space gains on the number of input Sbeams used the crosspower spectral matrix was simulated for a number of...environments; in the first example (figure 9) the noise field exhibited only a weak azimuthal dependance whereas in figure 10 the presence of a strong...interference at 06-1 implied a strong azimuthal dependance of tile noise field. Both result, showed an improvement in the beamspace array gain estimates as the
DFT based spatial multiplexing and maximum ratio transmission for mm-wawe large MIMO
Phan-Huy, D.-T.; Tölli, A.; Rajatheva, N.;
2014-01-01
By using large point-to-point multiple input multiple output (MIMO), spatial multiplexing of a large number of data streams in wireless communications using millimeter-waves (mm-waves) can be achieved. However, according to the antenna spacing and transmitter-receiver distance, the MIMO channel...
1979-08-01
r AD’ A076 235 WATKINS—JOHNSON Co SCOTYS VAL LEY CA F/S 9/5 N HIGH CONTRAST CRT.CU) AUG 79 6 A HOLNQUIST DAABO7—77—C—263 9 UNCLASSIFIED DEL.ET—TR—77...Air Force Systems Command A t t n : l) l . CA 2w) U I f iee ’ of \\ iva l Re ’~.ea r ch Andr ews AFI4 ( • ~~ii 4.~7 001 Washington , l ) .C. 20331
Receiver function estimated by maximum entropy deconvolution
吴庆举; 田小波; 张乃铃; 李卫平; 曾融生
2003-01-01
Maximum entropy deconvolution is presented to estimate receiver function, with the maximum entropy as the rule to determine auto-correlation and cross-correlation functions. The Toeplitz equation and Levinson algorithm are used to calculate the iterative formula of error-predicting filter, and receiver function is then estimated. During extrapolation, reflective coefficient is always less than 1, which keeps maximum entropy deconvolution stable. The maximum entropy of the data outside window increases the resolution of receiver function. Both synthetic and real seismograms show that maximum entropy deconvolution is an effective method to measure receiver function in time-domain.
A tropospheric ozone maximum over the equatorial Southern Indian Ocean
L. Zhang
2012-05-01
Full Text Available We examine the distribution of tropical tropospheric ozone (O_{3} from the Microwave Limb Sounder (MLS and the Tropospheric Emission Spectrometer (TES by using a global three-dimensional model of tropospheric chemistry (GEOS-Chem. MLS and TES observations of tropospheric O_{3} during 2005 to 2009 reveal a distinct, persistent O_{3} maximum, both in mixing ratio and tropospheric column, in May over the Equatorial Southern Indian Ocean (ESIO. The maximum is most pronounced in 2006 and 2008 and less evident in the other three years. This feature is also consistent with the total column O_{3} observations from the Ozone Mapping Instrument (OMI and the Atmospheric Infrared Sounder (AIRS. Model results reproduce the observed May O_{3} maximum and the associated interannual variability. The origin of the maximum reflects a complex interplay of chemical and dynamic factors. The O_{3} maximum is dominated by the O_{3} production driven by lightning nitrogen oxides (NO_{x} emissions, which accounts for 62% of the tropospheric column O_{3} in May 2006. We find the contribution from biomass burning, soil, anthropogenic and biogenic sources to the O_{3} maximum are rather small. The O_{3} productions in the lightning outflow from Central Africa and South America both peak in May and are directly responsible for the O_{3} maximum over the western ESIO. The lightning outflow from Equatorial Asia dominates over the eastern ESIO. The interannual variability of the O_{3} maximum is driven largely by the anomalous anti-cyclones over the southern Indian Ocean in May 2006 and 2008. The lightning outflow from Central Africa and South America is effectively entrained by the anti-cyclones followed by northward transport to the ESIO.
Maximum Power from a Solar Panel
Michael Miller
2010-01-01
Full Text Available Solar energy has become a promising alternative to conventional fossil fuel sources. Solar panels are used to collect solar radiation and convert it into electricity. One of the techniques used to maximize the effectiveness of this energy alternative is to maximize the power output of the solar collector. In this project the maximum power is calculated by determining the voltage and the current of maximum power. These quantities are determined by finding the maximum value for the equation for power using differentiation. After the maximum values are found for each time of day, each individual quantity, voltage of maximum power, current of maximum power, and maximum power is plotted as a function of the time of day.
Influence of maximum decking charge on intensity of blasting vibration
无
2006-01-01
Based on the character of short-time non-stationary random signal, the relationship between the maximum decking charge and energy distribution of blasting vibration signals was investigated by means of the wavelet packet method. Firstly, the characteristics of wavelet transform and wavelet packet analysis were described. Secondly, the blasting vibration signals were analyzed by wavelet packet based on software MATLAB, and the change of energy distribution curve at different frequency bands were obtained. Finally, the law of energy distribution of blasting vibration signals changing with the maximum decking charge was analyzed. The results show that with the increase of decking charge, the ratio of the energy of high frequency to total energy decreases, the dominant frequency bands of blasting vibration signals tend towards low frequency and blasting vibration does not depend on the maximum decking charge.
The maximum force in a column under constant speed compression
Kuzkin, Vitaly A
2015-01-01
Dynamic buckling of an elastic column under compression at constant speed is investigated assuming the first-mode buckling. Two cases are considered: (i) an imperfect column (Hoff's statement), and (ii) a perfect column having an initial lateral deflection. The range of parameters, where the maximum load supported by a column exceeds Euler static force is determined. In this range, the maximum load is represented as a function of the compression rate, slenderness ratio, and imperfection/initial deflection. Considering the results we answer the following question: "How slowly the column should be compressed in order to measure static load-bearing capacity?" This question is important for the proper setup of laboratory experiments and computer simulations of buckling. Additionally, it is shown that the behavior of a perfect column having an initial deflection differ significantlys form the behavior of an imperfect column. In particular, the dependence of the maximum force on the compression rate is non-monotoni...
Study of maximum pressure for composite hepta-tubular powders
M. C. Gupta
1959-10-01
Full Text Available In this paper the expressions for maximum pressure occurring positions in the case of composite hepta-tubular powers used in conventional guns and the corresponding conditions have been derived under certain conditions, viz., the value of n, the ratio of specific heats, has been assumed to be the same for both the charges and the covolume corrections have not been neglected.
Spatio-temporal observations of tertiary ozone maximum
V. F. Sofieva
2009-03-01
Full Text Available We present spatio-temporal distributions of tertiary ozone maximum (TOM, based on GOMOS (Global Ozone Monitoring by Occultation of Stars ozone measurements in 2002–2006. The tertiary ozone maximum is typically observed in the high-latitude winter mesosphere at altitude ~72 km. Although the explanation for this phenomenon has been found recently – low concentrations of odd-hydrogen cause the subsequent decrease in odd-oxygen losses – models have had significant deviations from existing observations until recently. Good coverage of polar night regions by GOMOS data has allowed for the first time obtaining spatial and temporal observational distributions of night-time ozone mixing ratio in the mesosphere.
The distributions obtained from GOMOS data have specific features, which are variable from year to year. In particular, due to a long lifetime of ozone in polar night conditions, the downward transport of polar air by the meridional circulation is clearly observed in the tertiary ozone maximum time series. Although the maximum tertiary ozone mixing ratio is achieved close to the polar night terminator (as predicted by the theory, TOM can be observed also at very high latitudes, not only in the beginning and at the end, but also in the middle of winter. We have compared the observational spatio-temporal distributions of tertiary ozone maximum with that obtained using WACCM (Whole Atmosphere Community Climate Model and found that the specific features are reproduced satisfactorily by the model.
Since ozone in the mesosphere is very sensitive to HO_{x} concentrations, energetic particle precipitation can significantly modify the shape of the ozone profiles. In particular, GOMOS observations have shown that the tertiary ozone maximum was temporarily destroyed during the January 2005 and December 2006 solar proton events as a result of the HO_{x} enhancement from the increased ionization.
1996-01-01
with a simple one-to-one mapping between resolution elements of a spatial phase modulator and resolution elements of the generated intensity pattern is provided. According to the invention a method is provided for synthesizing an intensity pattern with low loss of electromagnetic energy, comprising spatial...... modulation of electromagnetic radiation with a spatial phase mask for modulation of the phase of the incident eletromagnetic radiation by phasor values of individual resolution elements of the spatial phase mask, each phasor value being determined in such a way that the values of the Fourier transformed......The invention relates to a method and a system for synthesizing a prescribed intensity pattern based on phase contrast imaging that is not based on the assumption of prior art methods that the pahase shift phi is less than 1 radian. An improved method based on a simple imaging operation...
Tănase Alin-Eliodor
2014-08-01
Full Text Available This article focuses on computing techniques starting from trial balance data regarding financial key ratios. There are presented activity, liquidity, solvency and profitability financial key ratios. It is presented a computing methodology in three steps based on a trial balance.
Collins, Mimi
1997-01-01
Explores how human resource professionals, with above average offer/acceptance ratios, streamline their recruitment efforts. Profiles company strategies with internships, internal promotion, cooperative education programs, and how to get candidates to accept offers. Also discusses how to use the offer/acceptance ratio as a measure of program…
Akkerman, J. W.
1982-01-01
New mechanism alters compression ratio of internal-combustion engine according to load so that engine operates at top fuel efficiency. Ordinary gasoline, diesel and gas engines with their fixed compression ratios are inefficient at partial load and at low-speed full load. Mechanism ensures engines operate as efficiently under these conditions as they do at highload and high speed.
Wyer, J C; Salzinger, F H
1983-01-01
Many common management techniques have little use in managing a medical group practice. Ratio analysis, however, can easily be adapted to the group practice setting. Acting as broad-gauge indicators, financial ratios provide an early warning of potential problems and can be very useful in planning for future operations. The author has gathered a collection of financial ratios which were developed by participants at an education seminar presented for the Virginia Medical Group Management Association. Classified according to the human element, system component, and financial factor, the ratios provide a good sampling of measurements relevant to medical group practices and can serve as an example for custom-tailoring a ratio analysis system for your medical group.
The inverse maximum dynamic flow problem
BAGHERIAN; Mehri
2010-01-01
We consider the inverse maximum dynamic flow (IMDF) problem.IMDF problem can be described as: how to change the capacity vector of a dynamic network as little as possible so that a given feasible dynamic flow becomes a maximum dynamic flow.After discussing some characteristics of this problem,it is converted to a constrained minimum dynamic cut problem.Then an efficient algorithm which uses two maximum dynamic flow algorithms is proposed to solve the problem.
Maximum permissible voltage of YBCO coated conductors
Wen, J.; Lin, B.; Sheng, J.; Xu, J.; Jin, Z. [Department of Electrical Engineering, Shanghai Jiao Tong University, Shanghai (China); Hong, Z., E-mail: zhiyong.hong@sjtu.edu.cn [Department of Electrical Engineering, Shanghai Jiao Tong University, Shanghai (China); Wang, D.; Zhou, H.; Shen, X.; Shen, C. [Qingpu Power Supply Company, State Grid Shanghai Municipal Electric Power Company, Shanghai (China)
2014-06-15
Highlights: • We examine three kinds of tapes’ maximum permissible voltage. • We examine the relationship between quenching duration and maximum permissible voltage. • Continuous I{sub c} degradations under repetitive quenching where tapes reaching maximum permissible voltage. • The relationship between maximum permissible voltage and resistance, temperature. - Abstract: Superconducting fault current limiter (SFCL) could reduce short circuit currents in electrical power system. One of the most important thing in developing SFCL is to find out the maximum permissible voltage of each limiting element. The maximum permissible voltage is defined as the maximum voltage per unit length at which the YBCO coated conductors (CC) do not suffer from critical current (I{sub c}) degradation or burnout. In this research, the time of quenching process is changed and voltage is raised until the I{sub c} degradation or burnout happens. YBCO coated conductors test in the experiment are from American superconductor (AMSC) and Shanghai Jiao Tong University (SJTU). Along with the quenching duration increasing, the maximum permissible voltage of CC decreases. When quenching duration is 100 ms, the maximum permissible of SJTU CC, 12 mm AMSC CC and 4 mm AMSC CC are 0.72 V/cm, 0.52 V/cm and 1.2 V/cm respectively. Based on the results of samples, the whole length of CCs used in the design of a SFCL can be determined.
MinmingZhang; HuaZhou; YuZou
2004-01-01
OBJECTIVE To evaluate solitary pulmonary nodules (SPNs) using quantitative-dynamic contrast-enhancedfunctional-computed tomography(CT); and to illustrate its clinical efficacy in differential diagnosis of benign and malignant pulmonary nodules.METHODS Eighty patients with non-calcified SPNs (diameter, 5-30mm) were studied with dynamic contrast-enhanced CT. Patterns of the time-density curves (TDC) were assessed. The precontrast density, peak height in density (PH: the maximum value of the TDC) and S/A ratio (the ratio of the PH of SPN to aorta) were recorded. Precontrast density and enhancement patterns of SPNs were also recorded. Perfusion of the SPNs was calculated.RESULTS Malignant, benign and inflammatory nodules showed quite different patterns in the TDC. The PH and S/A ratios of the malignant and inflammatory nodules were significantly higher than that of the benig nnodules (P<0.001; P<0.001), while no statistical difference of either the PH or S/A ratio was found between the malignant and inflammatory nodules. Precontrast density of the inflammatory nodules was lower than that of the malignant nodules (P <0.05). Both the malignant and inflammatory nodules showed significantly higher perfusions than that of the benign nodules (P<0.01; P<0.01). However, the difference between the peffusion of the malignant nodules and inflammatory nodules was not significant.CONCLUSION Dynamic contrast-enhanced functional CT can provide quantitative information regarding blood flow patterns of SPNs and proved to be an alternate non-invasive option in the evaluation and management of solitary pulmonary nodules.
MSClique: Multiple Structure Discovery through the Maximum Weighted Clique Problem.
Sanroma, Gerard; Penate-Sanchez, Adrian; Alquézar, René; Serratosa, Francesc; Moreno-Noguer, Francesc; Andrade-Cetto, Juan; González Ballester, Miguel Ángel
2016-01-01
We present a novel approach for feature correspondence and multiple structure discovery in computer vision. In contrast to existing methods, we exploit the fact that point-sets on the same structure usually lie close to each other, thus forming clusters in the image. Given a pair of input images, we initially extract points of interest and extract hierarchical representations by agglomerative clustering. We use the maximum weighted clique problem to find the set of corresponding clusters with maximum number of inliers representing the multiple structures at the correct scales. Our method is parameter-free and only needs two sets of points along with their tentative correspondences, thus being extremely easy to use. We demonstrate the effectiveness of our method in multiple-structure fitting experiments in both publicly available and in-house datasets. As shown in the experiments, our approach finds a higher number of structures containing fewer outliers compared to state-of-the-art methods.
Generalised maximum entropy and heterogeneous technologies
Oude Lansink, A.G.J.M.
1999-01-01
Generalised maximum entropy methods are used to estimate a dual model of production on panel data of Dutch cash crop farms over the period 1970-1992. The generalised maximum entropy approach allows a coherent system of input demand and output supply equations to be estimated for each farm in the sam
20 CFR 229.48 - Family maximum.
2010-04-01
... month on one person's earnings record is limited. This limited amount is called the family maximum. The family maximum used to adjust the social security overall minimum rate is based on the employee's Overall..., when any of the persons entitled to benefits on the insured individual's compensation would, except...
The maximum rotation of a galactic disc
Bottema, R
1997-01-01
The observed stellar velocity dispersions of galactic discs show that the maximum rotation of a disc is on average 63% of the observed maximum rotation. This criterion can, however, not be applied to small or low surface brightness (LSB) galaxies because such systems show, in general, a continuously
Printing Detecting Algorithm Basing on Maximum Degree of Recognition
Hu Zhang
2013-04-01
Full Text Available In modern packaging, printing industry, due to effects of the properties of the strip itself and the ambient light, strip background color and the color of the printing line, the low contrast boundaries of the strip on both sides and so on, the traditional digital qualitative detection and control to the correction system does not meet the comprehensive requirements. This paper aims to study the detection of a continuous line, discontinuous line and color dividing line on the strip, and because of low contrast between background color and dividing line, we proposed an innovative solution and implementation. This article discusses a new algorithm basing on maximum degree of recognition and optimal light source search algorithm, and we simulated this in MATLAB, finally, we completed the physical testing of the overall system.
Duality of Maximum Entropy and Minimum Divergence
Shinto Eguchi
2014-06-01
Full Text Available We discuss a special class of generalized divergence measures by the use of generator functions. Any divergence measure in the class is separated into the difference between cross and diagonal entropy. The diagonal entropy measure in the class associates with a model of maximum entropy distributions; the divergence measure leads to statistical estimation via minimization, for arbitrarily giving a statistical model. The dualistic relationship between the maximum entropy model and the minimum divergence estimation is explored in the framework of information geometry. The model of maximum entropy distributions is characterized to be totally geodesic with respect to the linear connection associated with the divergence. A natural extension for the classical theory for the maximum likelihood method under the maximum entropy model in terms of the Boltzmann-Gibbs-Shannon entropy is given. We discuss the duality in detail for Tsallis entropy as a typical example.
Svendsen, Anders Jørgen; Holmskov, U; Bro, Peter
1995-01-01
hitherto unnoted differences between controls and patients with either rheumatoid arthritis or systemic lupus erythematosus. For this we use simple, but unconventional, graphic representations of the data, based on difference plots and ratio plots. Differences between patients with Burkitt's lymphoma...... and systemic lupus erythematosus from another previously published study (Macanovic, M. and Lachmann, P.J. (1979) Clin. Exp. Immunol. 38, 274) are also represented using ratio plots. Our observations indicate that analysis by regression analysis may often be misleading....
Piper, T; Piper, J
2012-09-01
Axial phase-darkfield-contrast (APDC) has been developed as an illumination technique in light microscopy which promises significant improvements and a higher variability in imaging of several transparent 'problem specimens'. With this method, a phase contrast image is optically superimposed on an axial darkfield image so that a partial image based on the principal zeroth order maximum (phase contrast) interferes with an image, which is based on the secondary maxima (axial darkfield). The background brightness and character of the resulting image can be continuously modulated from a phase contrast-dominated to a darkfield-dominated character. In order to achieve this illumination mode, normal objectives for phase contrast have to be fitted with an additional central light stopper needed for axial (central) darkfield illumination. In corresponding condenser light masks, a small perforation has to be added in the centre of the phase contrast providing light annulus. These light modulating elements are properly aligned when the central perforation is congruent with the objective's light stop and the light annulus is conjugate with the phase ring. The breadth of the condenser light annulus and thus the intensity of the phase contrast partial image can be regulated with the aperture diaphragm. Additional contrast effects can be achieved when both illuminating light components are filtered at different colours. In this technique, the axial resolution (depth of field) is significantly enhanced and the specimen's three-dimensional appearance is accentuated with improved clarity as well as fine details at the given resolution limit. Typical artefacts associated with phase contrast and darkfield illumination are reduced in our methods.
Maximum Work of Free-Piston Stirling Engine Generators
Kojima, Shinji
2017-04-01
Using the method of adjoint equations described in Ref. [1], we have calculated the maximum thermal efficiencies that are theoretically attainable by free-piston Stirling and Carnot engine generators by considering the work loss due to friction and Joule heat. The net work done by the Carnot cycle is negative even when the duration of heat addition is optimized to give the maximum amount of heat addition, which is the same situation for the Brayton cycle described in our previous paper. For the Stirling cycle, the net work done is positive, and the thermal efficiency is greater than that of the Otto cycle described in our previous paper by a factor of about 2.7-1.4 for compression ratios of 5-30. The Stirling cycle is much better than the Otto, Brayton, and Carnot cycles. We have found that the optimized piston trajectories of the isothermal, isobaric, and adiabatic processes are the same when the compression ratio and the maximum volume of the same working fluid of the three processes are the same, which has facilitated the present analysis because the optimized piston trajectories of the Carnot and Stirling cycles are the same as those of the Brayton and Otto cycles, respectively.
George Marsaglia
2006-05-01
Full Text Available This article extends and amplifies on results from a paper of over forty years ago. It provides software for evaluating the density and distribution functions of the ratio z/w for any two jointly normal variates z,w, and provides details on methods for transforming a general ratio z/w into a standard form, (a+x/(b+y , with x and y independent standard normal and a, b non-negative constants. It discusses handling general ratios when, in theory, none of the moments exist yet practical considerations suggest there should be approximations whose adequacy can be verified by means of the included software. These approximations show that many of the ratios of normal variates encountered in practice can themselves be taken as normally distributed. A practical rule is developed: If a < 2.256 and 4 < b then the ratio (a+x/(b+y is itself approximately normally distributed with mean μ = a/(1.01b − .2713 and variance 2 = (a2 + 1/(b2 + .108b − 3.795 − μ2.
George Marsaglia
2006-05-01
Full Text Available This article extends and amplifies on results from a paper of over forty years ago. It provides software for evaluating the density and distribution functions of the ratio z/w for any two jointly normal variates z,w, and provides details on methods for transforming a general ratio z/w into a standard form, (a+x/(b+y , with x and y independent standard normal and a, b non-negative constants. It discusses handling general ratios when, in theory, none of the moments exist yet practical considerations suggest there should be approximations whose adequacy can be verified by means of the included software. These approximations show that many of the ratios of normal variates encountered in practice can themselves be taken as normally distributed. A practical rule is developed: If a < 2.256 and 4 < b then the ratio (a+x/(b+y is itself approximately normally distributed with mean μ = a/(1.01b - .2713 and variance σ2 = (a2 + 1/(b2 + .108b - 3.795 μ2.
Hojamberdiev, Mirabbos; Bekheet, Maged F; Zahedi, Ehsan; Wagata, Hajime; Vequizo, Junie Jhon M; Yamakata, Akira; Yubuta, Kunio; Gurlo, Aleksander; Domen, Kazunari; Teshima, Katsuya
2016-08-02
The effect of the Ta/Nb ratio in the (111)-layered B-site deficient hexagonal perovskite Ba5Nb4-xTaxO15 (0 ≤ x ≤ 4) crystals grown by a KCl flux method on visible-light-induced photocatalytic water oxidation activity of their oxynitride derivatives BaNb1-xTaxO2N (0 ≤ x ≤ 1) was investigated. The Rietveld refinement of X-ray data revealed that all Ba5Nb4-xTaxO15 samples were well crystallized in the space group P3[combining macron]m1 (no. 164). Phase-pure BaNb1-xTaxO2N (0 ≤ x ≤ 1) porous structures were obtained by nitridation of the flux-grown oxide crystals at 950 °C for 20, 25, 30, 35, and 40 h, respectively. The absorption edge of BaNb1-xTaxO2N (0 ≤ x ≤ 1) was slightly shifted from 720 to 690 nm with the increasing Ta/Nb ratio. The O2 evolution rate gradually progressed and reached the highest value (127.24 μmol in the first 2 h) with the Ta content up to 50 mol% but decreased at 75 and 100 mol% presumably due to the reduced specific surface area and high density of structural defects, such as grain boundaries acting as recombination centers, originated from high-temperature nitridation for prolonged periods. Transient absorption spectroscopy provided evidence for the effect of the Ta/Nb ratio on the behavior and energy states of photogenerated charge carriers, indicating a direct correlation with photocatalytic water oxidation activity of BaNb1-xTaxO2N.
The Value of Contrast Echocardiography
Shannon C. Treiber
2016-01-01
Full Text Available Purpose: There is much evidence-based research proving the effectiveness of contrast echocardiography, but there are still questions and concerns about its specific uses. This study tested the effectiveness of contrast echocardiography in defining the left ventricular endocardial border. Methods: From 30 patients, a total of 60 echocardiograms –– 30 with and 30 without use of contrast –– were retrospectively reviewed by four blinded cardiologists with advanced training in echocardiography. No single cardiologist reviewed contrast and noncontrast images of the same patient. Each set of 30 echocardiograms was then studied for wall-motion scoring. Visualization of left ventricular wall segments and a global visualization confidence level of interpretation were recorded. Results: Of all wall segments (N = 510, 91% were visualized in echocardiograms with use of contrast, whereas 75% of the walls were visualized in echocardiograms without contrast (P < 0.001. Of 30 examinations, 17 contrast echocardiograms were read with high confidence compared to 6 without contrast use (P = 0.004. The number of walls visualized with contrast was increased in 18 patients (60%, whereas noncontrast echocardiograms yielded more visualized walls in 6 patients (20%, P = 0.002. Conclusions: This study demonstrates that contrast is valuable to echocardiographic imaging. Its use should be supported throughout echocardiography clinics and encouraged in certain patients for whom resting and stress echocardiography results without contrast often prove uninterpretable.
Kjærgaard, Søren; Canudas-Romo, Vladimir
2017-01-01
, the prospective potential support ratio usually focuses on the current mortality schedule, or period life expectancy. Instead, in this paper we look at the actual mortality experienced by cohorts in a population, using cohort life tables. We analyse differences between the two perspectives using mortality models......, historical data, and forecasted data. Cohort life expectancy takes future mortality improvements into account, unlike period life expectancy, leading to a higher prospective potential support ratio. Our results indicate that using cohort instead of period life expectancy returns around 0.5 extra younger...
A dual method for maximum entropy restoration
Smith, C. B.
1979-01-01
A simple iterative dual algorithm for maximum entropy image restoration is presented. The dual algorithm involves fewer parameters than conventional minimization in the image space. Minicomputer test results for Fourier synthesis with inadequate phantom data are given.
Maximum Throughput in Multiple-Antenna Systems
Zamani, Mahdi
2012-01-01
The point-to-point multiple-antenna channel is investigated in uncorrelated block fading environment with Rayleigh distribution. The maximum throughput and maximum expected-rate of this channel are derived under the assumption that the transmitter is oblivious to the channel state information (CSI), however, the receiver has perfect CSI. First, we prove that in multiple-input single-output (MISO) channels, the optimum transmission strategy maximizing the throughput is to use all available antennas and perform equal power allocation with uncorrelated signals. Furthermore, to increase the expected-rate, multi-layer coding is applied. Analogously, we establish that sending uncorrelated signals and performing equal power allocation across all available antennas at each layer is optimum. A closed form expression for the maximum continuous-layer expected-rate of MISO channels is also obtained. Moreover, we investigate multiple-input multiple-output (MIMO) channels, and formulate the maximum throughput in the asympt...
Photoemission spectromicroscopy with MAXIMUM at Wisconsin
Ng, W.; Ray-Chaudhuri, A.K.; Cole, R.K.; Wallace, J.; Crossley, S.; Crossley, D.; Chen, G.; Green, M.; Guo, J.; Hansen, R.W.C.; Cerrina, F.; Margaritondo, G. (Dept. of Electrical Engineering, Dept. of Physics and Synchrotron Radiation Center, Univ. of Wisconsin, Madison (USA)); Underwood, J.H.; Korthright, J.; Perera, R.C.C. (Center for X-ray Optics, Accelerator and Fusion Research Div., Lawrence Berkeley Lab., CA (USA))
1990-06-01
We describe the development of the scanning photoemission spectromicroscope MAXIMUM at the Wisoncsin Synchrotron Radiation Center, which uses radiation from a 30-period undulator. The article includes a discussion of the first tests after the initial commissioning. (orig.).
Maximum-likelihood method in quantum estimation
Paris, M G A; Sacchi, M F
2001-01-01
The maximum-likelihood method for quantum estimation is reviewed and applied to the reconstruction of density matrix of spin and radiation as well as to the determination of several parameters of interest in quantum optics.
Choi, I. W.; Kim, I J.; Pae, K. H.; Nam, K. H.; Lee, C.-L.; Yun, H.; Kim, H. T.; Lee, S. K.; Yu, T. J.; Sung, J. H.; Lee, J. [Advanced Photonics Research Institute, Gwangju Institute of Science and Technology, Gwangju 500-712 (Korea, Republic of); Pirozhkov, A. S.; Ogura, K.; Orimo, S.; Daido, H. [Quantum Beam Science Directorate, Japan Atomic Energy Agency, Kizugawa, Kyoto 619-0215 (Japan)
2011-10-31
We report the manufacturing of an (ultra-)thin foil target made of conjugated polymer, poly(9,9'-dioctylfluorene-co-benzothiadiazole) (F8BT), and the simultaneous observation of laser-accelerated ions and second harmonic radiation, when irradiated with ultrahigh-contrast laser pulse at a maximum intensity of 4 x 10{sup 19 }W/cm{sup 2}. Maximum proton energy of 8 MeV is achieved along the target normal direction. Strong second harmonic with over 6% energy ratio compared to fundamental is emitted along the specular direction. Two-dimensional particle-in-cell simulations confirm the simultaneous generation of protons and high-order harmonics, which demonstrates the feasibility of applications requiring particle and radiation sources at once, effectively using the same laser and target.
The maximum entropy technique. System's statistical description
Belashev, B Z
2002-01-01
The maximum entropy technique (MENT) is applied for searching the distribution functions of physical values. MENT takes into consideration the demand of maximum entropy, the characteristics of the system and the connection conditions, naturally. It is allowed to apply MENT for statistical description of closed and open systems. The examples in which MENT had been used for the description of the equilibrium and nonequilibrium states and the states far from the thermodynamical equilibrium are considered
19 CFR 114.23 - Maximum period.
2010-04-01
... 19 Customs Duties 1 2010-04-01 2010-04-01 false Maximum period. 114.23 Section 114.23 Customs... CARNETS Processing of Carnets § 114.23 Maximum period. (a) A.T.A. carnet. No A.T.A. carnet with a period of validity exceeding 1 year from date of issue shall be accepted. This period of validity cannot be...
Maximum-Likelihood Detection Of Noncoherent CPM
Divsalar, Dariush; Simon, Marvin K.
1993-01-01
Simplified detectors proposed for use in maximum-likelihood-sequence detection of symbols in alphabet of size M transmitted by uncoded, full-response continuous phase modulation over radio channel with additive white Gaussian noise. Structures of receivers derived from particular interpretation of maximum-likelihood metrics. Receivers include front ends, structures of which depends only on M, analogous to those in receivers of coherent CPM. Parts of receivers following front ends have structures, complexity of which would depend on N.
SEXUAL DIMORPHISM OF MAXIMUM FEMORAL LENGTH
Pandya A M
2011-04-01
Full Text Available Sexual identification from the skeletal parts has medico legal and anthropological importance. Present study aims to obtain values of maximum femoral length and to evaluate its possible usefulness in determining correct sexual identification. Study sample consisted of 184 dry, normal, adult, human femora (136 male & 48 female from skeletal collections of Anatomy department, M. P. Shah Medical College, Jamnagar, Gujarat. Maximum length of femur was considered as maximum vertical distance between upper end of head of femur and the lowest point on femoral condyle, measured with the osteometric board. Mean Values obtained were, 451.81 and 417.48 for right male and female, and 453.35 and 420.44 for left male and female respectively. Higher value in male was statistically highly significant (P< 0.001 on both sides. Demarking point (D.P. analysis of the data showed that right femora with maximum length more than 476.70 were definitely male and less than 379.99 were definitely female; while for left bones, femora with maximum length more than 484.49 were definitely male and less than 385.73 were definitely female. Maximum length identified 13.43% of right male femora, 4.35% of right female femora, 7.25% of left male femora and 8% of left female femora. [National J of Med Res 2011; 1(2.000: 67-70
Miles, T. R.; Haslum, M. N.; Wheeler, T. J.
1998-01-01
A study involving 11,804 British children (age 10) found that when specified criteria for dyslexia were used, 269 children qualified as dyslexic. These included 223 boys and 46 girls, for a ratio of 4.51 to 1. Difficulties in interpreting these data are discussed and a defense of the criteria is provided. (Author/CR)
PO de Wet
2005-06-01
Full Text Available The rectilinear Steiner ratio was shown to be 3/2 by Hwang [Hwang FK, 1976, On Steiner minimal trees with rectilinear distance, SIAM Journal on Applied Mathematics, 30, pp. 104– 114.]. We use continuity and introduce restricted point sets to obtain an alternative, short and self-contained proof of this result.
Nilsson, P.; Almen, T.; Golman, K.; Jonsson, K.; Nyman, U.
The acute intravenous toxicity (i.v. LD/sub 50/) of solutions of the ratio 1.5 contrast media metrizoate or diatrizoate and the ratio 3.0 contrast medium metrizamide was determined in mice with and without the addition of local anesthetics to the solutions. The two local anesthetics mepivacaine or lidocaine were added to final concentrations up to 2.0 mg/ml of the contrast medium solutions. This corresponds to clinically used concentrations. All additions of local anesthetics to the solutions increased the mortalities caused by the contrast medium solutions. Addition of local anesthetics to a final concentration of 2 mg/ml approximately doubled the acute intravenous toxicity of the contrast media. The ratio 3 contrast media produce less hypertonic solutions than the ratio 1.5 contrast media and should be preferred for angiography because they cause less pain and do not require the addition of local anesthetics which increase the acute toxicity of the solutions.
Diagnostic value of dynamic contrast-enhanced MRI for submucosal palatal tumors
Matsuzaki, Hidenobu, E-mail: hidenobu@md.okayama-u.ac.jp [Department of Oral Diagnosis and Dentomaxillofacial Radiology, Okayama University Hospital, 5-1 Shikata-cho, 2-chome, Kita-ku, Okayama 700-8525 (Japan); Yanagi, Yoshinobu, E-mail: ya7@md.okayama-u.ac.jp [Department of Oral Diagnosis and Dentomaxillofacial Radiology, Okayama University Hospital, 5-1 Shikata-cho, 2-chome, Kita-ku, Okayama 700-8525 (Japan); Hara, Marina, E-mail: hara-m@cc.okayama-u.ac.jp [Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 5-1 Shikata-cho, 2-chome, Kita-ku, Okayama 700-8525 (Japan); Katase, Naoki, E-mail: katase-n@cc.okayama-u.ac.jp [Department of Oral Pathology and Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 5-1 Shikata-cho, 2-chome, Kita-ku, Okayama 700-8525 (Japan); Hisatomi, Miki, E-mail: tomi@md.okayama-u.ac.jp [Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 5-1 Shikata-cho, 2-chome, Kita-ku, Okayama 700-8525 (Japan); Unetsubo, Teruhisa, E-mail: gmd17107@s.okadai.jp [Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 5-1 Shikata-cho, 2-chome, Kita-ku, Okayama 700-8525 (Japan); Konouchi, Hironobu, E-mail: kono@md.okayama-u.ac.jp [Department of Oral Diagnosis and Dentomaxillofacial Radiology, Okayama University Hospital, 5-1 Shikata-cho, 2-chome, Kita-ku, Okayama 700-8525 (Japan); Takenobu, Toshihiko, E-mail: takenobu@kcgh.gr.jp [Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 5-1 Shikata-cho, 2-chome, Kita-ku, Okayama 700-8525 (Japan); and others
2012-11-15
Objectives: To evaluate the diagnostic value of dynamic contrast-enhanced MRI (DCE-MRI) for differentiating between benign and malignant tumors in the palate. Materials and methods: 26 patients with submucosal palatal tumors were preoperatively examined using DCE-MRI. Their maximum contrast index (CImax), time of CImax (Tmax), and washout ratios (WR300 and WR600) were determined from contrast index curves. The submucosal palatal tumors were divided into two groups according to their Tmax values: the early enhancement group (Tmax < 300 s) consisted of 9 malignant tumors and 6 benign tumors, while the late enhancement group (Tmax {>=} 300 s) included one malignant tumor and 10 benign tumors. We compared the following DCE-MRI parameters between the benign and malignant tumors: CImax and Tmax in all cases and CImax, Tmax, and the washout ratios in the early enhancement group. In addition, we performed a regression analysis of the relationships between tumor size and DCE-MRI parameters; i.e., CImax, Tmax, and washout ratios, among the malignant salivary gland tumors and pleomorphic adenomas. Results: In all cases and the early enhancement group, significant differences in Tmax were detected between the benign and malignant tumors (P < 0.001 and P < 0.05, respectively), and the optimal Tmax cutoff value for differentiating between them was found to be 165 s. None of the other parameters displayed significant differences between the benign and malignant tumors. Only the WR600 of the pleomorphic adenomas was significantly correlated with tumor size (R{sup 2} = 0.92, P < 0.001). Conclusions: Tmax is a useful parameter for distinguishing between benign and malignant submucosal palatal tumors.
The biochemical composition of plankton in a subsurface chlorophyll maximum
Dortch, Quay
1987-06-01
The biochemical composition of plankton at a station with a deep, subsurface chlorophyll maximum (SCM) below a nitrogen-depleted surface layer off the Washington coast was determined in order to answer long-standing questions about the nature and causes of SCM. The chlorophyll maximum did not correspond to a protein-biomass maximum, and chlorophyll: protein ratios indicate that only in the SCM were phytoplankton a major constituent of the total biomass. Ratios of free amino acids: protein in the particulate matter were high at all depths in the euphotic zone. From this it can be concluded that phytoplankton in the SCM are N-sufficient, since they make up 80-90% of the biomass there. Above and below the SCM, where non-phytoplankton predominate, the state of N deficiency or sufficiency of the phytoplankton cannot be ascertained until more is known about how the chemical composition of phytoplankton, zooplankton and bacteria are related. However, if it is assumed that very N-sufficient zooplankton and bacteria would not coexist with very N-deficient phytoplankton, then it seems likely that the phytoplankton were also N-sufficient or nearly so. Thus, the biochemical indicators do not support the hypothesis that the SCM forms because it represents the only layer in the water column with adequate N and light for phytoplankton growth. Comparison of the chlorophyll: protein ratios with those from cultures and from other regions suggests that oligotrophic areas have a much higher proportion of non-phytoplankton biomass than do eutrophic areas.
Fukuyama, Atsushi; Isoda, Haruo; Morita, Kento; Mori, Marika; Watanabe, Tomoya; Ishiguro, Kenta; Komori, Yoshiaki; Kosugi, Takafumi
2017-10-10
We aim to elucidate the effect of spatial resolution of three-dimensional cine phase contrast magnetic resonance (3D cine PC MR) imaging on the accuracy of the blood flow analysis, and examine the optimal setting for spatial resolution using flow phantoms. The flow phantom has five types of acrylic pipes that represent human blood vessels (inner diameters: 15, 12, 9, 6, and 3 mm). The pipes were fixed with 1% agarose containing 0.025 mol/L gadolinium contrast agent. A blood-mimicking fluid with human blood property values was circulated through the pipes at a steady flow. Magnetic resonance (MR) images (three-directional phase images with speed information and magnitude images for information of shape) were acquired using the 3-Tesla MR system and receiving coil. Temporal changes in spatially-averaged velocity and maximum velocity were calculated using hemodynamic analysis software. We calculated the error rates of the flow velocities based on the volume flow rates measured with a flowmeter and examined measurement accuracy. When the acrylic pipe was the size of the thoracicoabdominal or cervical artery and the ratio of pixel size for the pipe was set at 30% or lower, spatially-averaged velocity measurements were highly accurate. When the pixel size ratio was set at 10% or lower, maximum velocity could be measured with high accuracy. It was difficult to accurately measure maximum velocity of the 3-mm pipe, which was the size of an intracranial major artery, but the error for spatially-averaged velocity was 20% or less. Flow velocity measurement accuracy of 3D cine PC MR imaging for pipes with inner sizes equivalent to vessels in the cervical and thoracicoabdominal arteries is good. The flow velocity accuracy for the pipe with a 3-mm-diameter that is equivalent to major intracranial arteries is poor for maximum velocity, but it is relatively good for spatially-averaged velocity.
Takahashi, N.; Sato, M.; Niitsu, M.; Saida, Y. [Univ. of Tsukuba Hospital, Ibaraki (Japan). Dept. of Radiology
2004-10-01
Purpose: To evaluate image subtraction in a three-dimensional contrast-enhanced magnetic resonance angiography (3D CE-MRA) using fat suppression for the hemodialysis fistula. Material and Methods: Fifteen patients suffering from hemodialysis fistula dysfunction were imaged with 3D CE-MRA using fat suppression and digital subtraction angiography (DSA). Non-subtracted and subtracted MRA images using maximum intensity projection (MIP) were constructed and the validity of the MRA interpretations of the degree of vascular stenoses was evaluated using DSA as the standard of reference. Image quality was assessed using qualitative analysis (vessel contrast) and quantitative analysis (contrast-to-noise ratio (CNR) of the vessel versus the background). Results: In the vessels with stenosis of 50% or greater, the sensitivity and specificity of the non-subtracted MRA were 89.5% and 81.8%, respectively, and of the subtracted MRA 89.5% and 86.4%, respectively. There was no significant difference in the detectability of stenoses between either MRA. The vessel contrast of the anterior interosseous artery and the CNR of the anterior interosseous artery versus the background on the subtracted MRA were significantly superior to those on the non-subtracted MRA. With regard to the radial artery and cephalic vein, there was no significant difference in the vessel contrast and CNR between either MRA. Conclusion: Both subtracted and non-subtracted MRA techniques are useful in detecting hemodialysis fistula dysfunction.
GA-BASED MAXIMUM POWER DISSIPATION ESTIMATION OF VLSI SEQUENTIAL CIRCUITS OF ARBITRARY DELAY MODELS
Lu Junming; Lin Zhenghui
2002-01-01
In this paper, the glitching activity and process variations in the maximum power dissipation estimation of CMOS circuits are introduced. Given a circuit and the gate library,a new Genetic Algorithm (GA)-based technique is developed to determine the maximum power dissipation from a statistical point of view. The simulation on ISCAS-89 benchmarks shows that the ratio of the maximum power dissipation with glitching activity over the maximum power under zero-delay model ranges from 1.18 to 4.02. Compared with the traditional Monte Carlo-based technique, the new approach presented in this paper is more effective.
GA—BASED MAXIMUM POWER DISSIPATION ESTIMATION OF VLSI SEQUENTIAL CIRCUITS OF ARBITRARY DELAY MODELS
LuJunming; LinZhenghui
2002-01-01
In this paper,the glitching activity and process variations in the maximum power dissipation estimation of CMOS circulits are introduced.Given a circuit and the gate library,a new Genetic Algorithm (GA)-based technique is developed to determine the maximum power dissipation from a statistical point of view.The simulation on ISCAS-89 benchmarks shows that the ratio of the maximum power dissipation with glitching activity over the maximum power under zero-delay model ranges from 1.18 to 4.02.Compared with the traditional Monte Carlo-based technique,the new approach presented in this paper is more effective.
Maximum Likelihood Joint Tracking and Association in Strong Clutter
Leonid I. Perlovsky
2013-01-01
Full Text Available We have developed a maximum likelihood formulation for a joint detection, tracking and association problem. An efficient non-combinatorial algorithm for this problem is developed in case of strong clutter for radar data. By using an iterative procedure of the dynamic logic process “from vague-to-crisp” explained in the paper, the new tracker overcomes the combinatorial complexity of tracking in highly-cluttered scenarios and results in an orders-of-magnitude improvement in signal-to-clutter ratio.
Maximum Likelihood Joint Tracking and Association in Strong Clutter
Leonid I. Perlovsky
2013-01-01
Full Text Available We have developed a maximum likelihood formulation for a joint detection, tracking and association problem. An efficient non‐combinatorial algorithm for this problem is developed in case of strong clutter for radar data. By using an iterative procedure of the dynamic logic process “from vague‐to‐crisp” explained in the paper, the new tracker overcomes the combinatorial complexity of tracking in highly‐cluttered scenarios and results in an orders‐of‐magnitude improvement in signal‐ to‐clutter ratio.
Functional imaging with MR T1 contrast: a feasibility study with blood-pool contrast agent
Majos, Agata; Stefanczyk, Ludomir [Medical University of Lodz, Radiology Department, Lodz (Poland); Bogorodzki, Piotr; Piatkowska-Janko, Ewa; Kurjata, Robert [Warsaw University of Technology, Institute of Radioelectronics, Warsaw (Poland); Wolak, Tomasz [Institute of Physiology and Pathology of Hearing, Warsaw (Poland)
2009-04-15
The aim of this study was to prove the concept of using a long intravenous half-life blood-pool T1 contrast agent as a new functional imaging method. For each of ten healthy subjects, two dynamic magnetic resonance (MR) protocols were carried out: (1) a reference run with a typical T2* echo-planar imaging (EPI) sequence based on the blood oxygenation level-dependent (BOLD) effect and (2) a run with a T1-sensitive three-dimensional (3D) gradient-echo (GRE) sequence using cerebral blood volume (CBV) contrast after intravenous administration of a contrast agent containing a chelate of gadolinium diethylene-triamine-pentaacetate with a phosphono-oxymethyl substituent. All sequences were performed during the execution of a block-type finger-tapping paradigm. SPM5 software was used for statistical analysis. For both runs maximum activations (peak Z-score = 5.5, cluster size 3,449 voxels) were localized in the left postcentral gyrus. Visual inspection of respective signal amplitudes suggests the T1 contrast to be substantially smaller than EPI (0.5% vs 1%). A new functional imaging method with potentially smaller image artefacts due to the nature of CBV contrast and characteristics of the T1 sequence was proposed and verified. (orig.)
Contrast-enhanced endoscopic ultrasonography
Reddy, Nischita K; Ioncica, Ana Maria; Saftoiu, Adrian;
2011-01-01
agents and their use in various endoscopic procedures in the gastrointestinal tract. Various applications of contrast-enhanced endoscopic ultrasonography include differentiating benign from malignant mediastinal lymphadenopathy, assessment of depth of invasion of esophageal, gastric and gall bladder...... sonography to depict tumor neovascularization can be increased by contrast agents. Contrast-enhanced harmonic imaging is a useful aid in identifying the tumor vasculature and studying pancreatic microperfusion. In the future, these techniques could potentially be used to quantify tumor perfusion, to assess...
Discourse Theory and "Contrastive Rhetoric."
Bar-Lev, Zev
1986-01-01
Appraises R. Kaplan's "contrastic rhetoric" in the light of a multilanguage research project on discourse structure. Concludes that Kaplan's specific analyses are in need of substantive revision. (FL)
Fuzzy-Contextual Contrast Enhancement.
Parihar, Anil; Verma, Om; Khanna, Chintan
2017-02-08
This paper presents contrast enhancement algorithms based on fuzzy contextual information of the images. We introduce fuzzy similarity index and fuzzy contrast factor to capture the neighborhood characteristics of a pixel. A new histogram, using fuzzy contrast factor of each pixel is developed, and termed as the fuzzy dissimilarity histogram (FDH). A cumulative distribution function (CDF) is formed with normalized values of FDH and used as a transfer function to obtain the contrast enhanced image. The algorithm gives good contrast enhancement and preserves the natural characteristic of the image. In order to develop a contextual intensity transfer function, we introduce a fuzzy membership function based on fuzzy similarity index and coefficient of variation of the image. The contextual intensity transfer function is designed using the fuzzy membership function to achieve final contrast enhanced image. The overall algorithm is referred as the fuzzy contextual contrast-enhancement (FCCE) algorithm. The proposed algorithms are compared with conventional and state-of-art contrast enhancement algorithms. The quantitative and visual assessment of the results is performed. The results of quantitative measures are statistically analyzed using t-test. The exhaustive experimentation and analysis show the proposed algorithm efficiently enhances contrast and yields in natural visual quality images.
Park, Hyunbin; Sim, Minseob; Kim, Shiho
2015-06-01
We propose a way of achieving maximum power and power-transfer efficiency from thermoelectric generators by optimized selection of maximum-power-point-tracking (MPPT) circuits composed of a boost-cascaded-with-buck converter. We investigated the effect of switch resistance on the MPPT performance of thermoelectric generators. The on-resistances of the switches affect the decrease in the conversion gain and reduce the maximum output power obtainable. Although the incremental values of the switch resistances are small, the resulting difference in the maximum duty ratio between the input and output powers is significant. For an MPPT controller composed of a boost converter with a practical nonideal switch, we need to monitor the output power instead of the input power to track the maximum power point of the thermoelectric generator. We provide a design strategy for MPPT controllers by considering the compromise in which a decrease in switch resistance causes an increase in the parasitic capacitance of the switch.
Refractive index contrast in porous silicon multilayers
Nava, R.; Mora, M.B. de la; Tagueena-Martinez, J. [Centro de Investigacion en Energia, Universidad Nacional Autonoma de Mexico, Temixco, Morelos (Mexico); Rio, J.A. del [Centro de Investigacion en Energia, Universidad Nacional Autonoma de Mexico, Temixco, Morelos (Mexico); Centro Morelense de Innovacion y Transferencia Tecnologica, Consejo de Ciencia y Tecnologia del Estado de Morelos (Mexico)
2009-07-15
Two of the most important properties of a porous silicon multilayer for photonic applications are flat interfaces and a relative large refractive index contrast between layers in the optical wavelength range. In this work, we studied the effect of the current density and HF electrolyte concentration on the refractive index of porous silicon. With the purpose of increasing the refractive index contrast in a multilayer, the refractive index of porous silicon produced at low current was studied in detail. The current density applied to produce the low porosity layers was limited in order to keep the electrolyte flow through the multilayer structure and to avoid deformation of layer interfaces. We found that an electrolyte composed of hydrofluoric acid, ethanol and glycerin in a ratio of 3:7:1 gives a refractive index contrast around 1.3/2.8 at 600 nm. Several multilayer structures with this refractive index contrast were fabricated, such as dielectric Bragg mirrors and microcavities. Reflectance spectra of the structures show the photonic quality of porous silicon multilayers produced under these electrochemical conditions. (copyright 2009 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)
Terasawa, Kazuaki; Hatcho, Atsushi
2008-06-20
In three-dimensional CT angiography (3D-CTA), good reproducibility can be obtained by maintaining the maximum CT numbers (HU) at a specified level. However, the correlation between the scan time and the injection time showed that the maximum CT numbers increased and varied due to the additional contrast enhancement effect from recirculation of the injected contrast medium for longer injection times when the dose of iodinated contrast medium per unit time (mgI/s) was maintained at a specified level based on the time-density curve (TDC) of the phantom. The amount of contrast medium employed at our hospital has been optimized based on an iodinated contrast medium dose per unit time providing a contrast enhancement effect of 300 HU in the middle cerebral artery. Using this standard, a TDC phantom was employed to obtain an iodinated contrast medium dose per unit time, permitting equivalent maximum CT values (used as standard values) to be obtained by changing the injection time. A contrast-enhancement technique that accounts for the variation in the scan time was evaluated. Strong correlations were observed between the scan time and the injection time (R2=0.969) and between the injection time and the dose of iodinated contrast medium per unit body weight (R2=0.994). We conclude that adjusting the dose of iodinated contrast medium per unit body weight per unit time according to the scan time permits optimization of the contrast-enhancement technique.
Modeling the Maximum Spreading of Liquid Droplets Impacting Wetting and Nonwetting Surfaces.
Lee, Jae Bong; Derome, Dominique; Guyer, Robert; Carmeliet, Jan
2016-02-09
Droplet impact has been imaged on different rigid, smooth, and rough substrates for three liquids with different viscosity and surface tension, with special attention to the lower impact velocity range. Of all studied parameters, only surface tension and viscosity, thus the liquid properties, clearly play a role in terms of the attained maximum spreading ratio of the impacting droplet. Surface roughness and type of surface (steel, aluminum, and parafilm) slightly affect the dynamic wettability and maximum spreading at low impact velocity. The dynamic contact angle at maximum spreading has been identified to properly characterize this dynamic spreading process, especially at low impact velocity where dynamic wetting plays an important role. The dynamic contact angle is found to be generally higher than the equilibrium contact angle, showing that statically wetting surfaces can become less wetting or even nonwetting under dynamic droplet impact. An improved energy balance model for maximum spreading ratio is proposed based on a correct analytical modeling of the time at maximum spreading, which determines the viscous dissipation. Experiments show that the time at maximum spreading decreases with impact velocity depending on the surface tension of the liquid, and a scaling with maximum spreading diameter and surface tension is proposed. A second improvement is based on the use of the dynamic contact angle at maximum spreading, instead of quasi-static contact angles, to describe the dynamic wetting process at low impact velocity. This improved model showed good agreement compared to experiments for the maximum spreading ratio versus impact velocity for different liquids, and a better prediction compared to other models in literature. In particular, scaling according to We(1/2) is found invalid for low velocities, since the curves bend over to higher maximum spreading ratios due to the dynamic wetting process.
Efficiency at Maximum Power of Low-Dissipation Carnot Engines
Esposito, Massimiliano; Kawai, Ryoichi; Lindenberg, Katja; van den Broeck, Christian
2010-10-01
We study the efficiency at maximum power, η*, of engines performing finite-time Carnot cycles between a hot and a cold reservoir at temperatures Th and Tc, respectively. For engines reaching Carnot efficiency ηC=1-Tc/Th in the reversible limit (long cycle time, zero dissipation), we find in the limit of low dissipation that η* is bounded from above by ηC/(2-ηC) and from below by ηC/2. These bounds are reached when the ratio of the dissipation during the cold and hot isothermal phases tend, respectively, to zero or infinity. For symmetric dissipation (ratio one) the Curzon-Ahlborn efficiency ηCA=1-Tc/Th is recovered.
Maximum tunneling velocities in symmetric double well potentials
Manz, Jörn; Schmidt, Burkhard; Yang, Yonggang
2014-01-01
We consider coherent tunneling of one-dimensional model systems in non-cyclic or cyclic symmetric double well potentials. Generic potentials are constructed which allow for analytical estimates of the quantum dynamics in the non-relativistic deep tunneling regime, in terms of the tunneling distance, barrier height and mass (or moment of inertia). For cyclic systems, the results may be scaled to agree well with periodic potentials for which semi-analytical results in terms of Mathieu functions exist. Starting from a wavepacket which is initially localized in one of the potential wells, the subsequent periodic tunneling is associated with tunneling velocities. These velocities (or angular velocities) are evaluated as the ratio of the flux densities versus the probability densities. The maximum velocities are found under the top of the barrier where they scale as the square root of the ratio of barrier height and mass (or moment of inertia), independent of the tunneling distance. They are applied exemplarily to ...
Efficiency at maximum power of low-dissipation Carnot engines.
Esposito, Massimiliano; Kawai, Ryoichi; Lindenberg, Katja; Van den Broeck, Christian
2010-10-01
We study the efficiency at maximum power, η*, of engines performing finite-time Carnot cycles between a hot and a cold reservoir at temperatures Th and Tc, respectively. For engines reaching Carnot efficiency ηC=1-Tc/Th in the reversible limit (long cycle time, zero dissipation), we find in the limit of low dissipation that η* is bounded from above by ηC/(2-ηC) and from below by ηC/2. These bounds are reached when the ratio of the dissipation during the cold and hot isothermal phases tend, respectively, to zero or infinity. For symmetric dissipation (ratio one) the Curzon-Ahlborn efficiency ηCA=1-√Tc/Th] is recovered.
Depletion studies of two contrasting D-2 reefs
Gillund, G.N.; Patel, C.
1980-01-01
The Nisku B and G pools are 2 W. Pembina D-2 pools with contrasting reservoir properties. Average porosity, permeability, and maximum thickness are 5%, 130 md, and 95 m; and 16.4%, 7100 md and 19 m, respectively. The results of the depletion model studies of waterflooding and miscible flooding and some of the problems that occurred during these studies are reviewed.
Maximum permissible voltage of YBCO coated conductors
Wen, J.; Lin, B.; Sheng, J.; Xu, J.; Jin, Z.; Hong, Z.; Wang, D.; Zhou, H.; Shen, X.; Shen, C.
2014-06-01
Superconducting fault current limiter (SFCL) could reduce short circuit currents in electrical power system. One of the most important thing in developing SFCL is to find out the maximum permissible voltage of each limiting element. The maximum permissible voltage is defined as the maximum voltage per unit length at which the YBCO coated conductors (CC) do not suffer from critical current (Ic) degradation or burnout. In this research, the time of quenching process is changed and voltage is raised until the Ic degradation or burnout happens. YBCO coated conductors test in the experiment are from American superconductor (AMSC) and Shanghai Jiao Tong University (SJTU). Along with the quenching duration increasing, the maximum permissible voltage of CC decreases. When quenching duration is 100 ms, the maximum permissible of SJTU CC, 12 mm AMSC CC and 4 mm AMSC CC are 0.72 V/cm, 0.52 V/cm and 1.2 V/cm respectively. Based on the results of samples, the whole length of CCs used in the design of a SFCL can be determined.
Computing Rooted and Unrooted Maximum Consistent Supertrees
van Iersel, Leo
2009-01-01
A chief problem in phylogenetics and database theory is the computation of a maximum consistent tree from a set of rooted or unrooted trees. A standard input are triplets, rooted binary trees on three leaves, or quartets, unrooted binary trees on four leaves. We give exact algorithms constructing rooted and unrooted maximum consistent supertrees in time O(2^n n^5 m^2 log(m)) for a set of m triplets (quartets), each one distinctly leaf-labeled by some subset of n labels. The algorithms extend to weighted triplets (quartets). We further present fast exact algorithms for constructing rooted and unrooted maximum consistent trees in polynomial space. Finally, for a set T of m rooted or unrooted trees with maximum degree D and distinctly leaf-labeled by some subset of a set L of n labels, we compute, in O(2^{mD} n^m m^5 n^6 log(m)) time, a tree distinctly leaf-labeled by a maximum-size subset X of L that all trees in T, when restricted to X, are consistent with.
Maximum magnitude earthquakes induced by fluid injection
McGarr, Arthur F.
2014-01-01
Analysis of numerous case histories of earthquake sequences induced by fluid injection at depth reveals that the maximum magnitude appears to be limited according to the total volume of fluid injected. Similarly, the maximum seismic moment seems to have an upper bound proportional to the total volume of injected fluid. Activities involving fluid injection include (1) hydraulic fracturing of shale formations or coal seams to extract gas and oil, (2) disposal of wastewater from these gas and oil activities by injection into deep aquifers, and (3) the development of enhanced geothermal systems by injecting water into hot, low-permeability rock. Of these three operations, wastewater disposal is observed to be associated with the largest earthquakes, with maximum magnitudes sometimes exceeding 5. To estimate the maximum earthquake that could be induced by a given fluid injection project, the rock mass is assumed to be fully saturated, brittle, to respond to injection with a sequence of earthquakes localized to the region weakened by the pore pressure increase of the injection operation and to have a Gutenberg-Richter magnitude distribution with a b value of 1. If these assumptions correctly describe the circumstances of the largest earthquake, then the maximum seismic moment is limited to the volume of injected liquid times the modulus of rigidity. Observations from the available case histories of earthquakes induced by fluid injection are consistent with this bound on seismic moment. In view of the uncertainties in this analysis, however, this should not be regarded as an absolute physical limit.
Maximum magnitude earthquakes induced by fluid injection
McGarr, A.
2014-02-01
Analysis of numerous case histories of earthquake sequences induced by fluid injection at depth reveals that the maximum magnitude appears to be limited according to the total volume of fluid injected. Similarly, the maximum seismic moment seems to have an upper bound proportional to the total volume of injected fluid. Activities involving fluid injection include (1) hydraulic fracturing of shale formations or coal seams to extract gas and oil, (2) disposal of wastewater from these gas and oil activities by injection into deep aquifers, and (3) the development of enhanced geothermal systems by injecting water into hot, low-permeability rock. Of these three operations, wastewater disposal is observed to be associated with the largest earthquakes, with maximum magnitudes sometimes exceeding 5. To estimate the maximum earthquake that could be induced by a given fluid injection project, the rock mass is assumed to be fully saturated, brittle, to respond to injection with a sequence of earthquakes localized to the region weakened by the pore pressure increase of the injection operation and to have a Gutenberg-Richter magnitude distribution with a b value of 1. If these assumptions correctly describe the circumstances of the largest earthquake, then the maximum seismic moment is limited to the volume of injected liquid times the modulus of rigidity. Observations from the available case histories of earthquakes induced by fluid injection are consistent with this bound on seismic moment. In view of the uncertainties in this analysis, however, this should not be regarded as an absolute physical limit.
Contrast enhanced cartilage imaging: Comparison of ionic and non-ionic contrast agents
Wiener, Edzard [Department of Radiology, Technical University Munich, Ismaninger Str. 22, D-81675 Munich (Germany)]. E-mail: ewiener@roe.med.tu-muenchen.de; Woertler, Klaus [Department of Radiology, Technical University Munich, Ismaninger Str. 22, D-81675 Munich (Germany); Weirich, Gregor [Institute of Pathology, Technical University Munich, Troger Str. 18, D-81675 Munich (Germany); Rummeny, Ernst J. [Department of Radiology, Technical University Munich, Ismaninger Str. 22, D-81675 Munich (Germany); Settles, Marcus [Department of Radiology, Technical University Munich, Ismaninger Str. 22, D-81675 Munich (Germany)
2007-07-15
Our objective was to compare relaxation effects, dynamics and spatial distributions of ionic and non-ionic contrast agents in articular cartilage at concentrations typically used for direct MR arthrography at 1.5 T. Dynamic MR-studies over 11 h were performed in 15 bovine patella specimens. For each of the contrast agents gadopentetate dimeglumine, gadobenate dimeglumine, gadoteridol and mangafodipir trinatrium three patellae were placed in 2.5 mmol/L contrast solution. Simultaneous measurements of T {sub 1} and T {sub 2} were performed every 30 min using a high-spatial-resolution 'MIX'-sequence. T {sub 1}, T {sub 2} and {delta}R {sub 1}, {delta}R {sub 2} profile plots across cartilage thickness were calculated to demonstrate the spatial and temporal distributions. The charge is one of the main factors which controls the amount of the contrast media diffusing into intact cartilage, but independent of the charge, the spatial distribution across cartilage thickness remains highly inhomogeneous even after 11 h of diffusion. The absolute {delta}R {sub 2}-effect in cartilage is at least as large as the {delta}R {sub 1}-effect for all contrast agents. Maximum changes were 5-12 s{sup -1} for {delta}R {sub 1} and 8-15 s{sup -1} for {delta}R {sub 2}. This study indicates that for morphologically intact cartilage only the amount of contrast agents within cartilage is determined by the charge but not the spatial distribution across cartilage thickness. In addition, {delta}R {sub 2} can be considered for quantification of contrast agent concentrations, since it is of the same magnitude and less time consuming to measure than {delta}R {sub 1}.
Maximum Multiflow in Wireless Network Coding
Zhou, Jin-Yi; Jiang, Yong; Zheng, Hai-Tao
2012-01-01
In a multihop wireless network, wireless interference is crucial to the maximum multiflow (MMF) problem, which studies the maximum throughput between multiple pairs of sources and sinks. In this paper, we observe that network coding could help to decrease the impacts of wireless interference, and propose a framework to study the MMF problem for multihop wireless networks with network coding. Firstly, a network model is set up to describe the new conflict relations modified by network coding. Then, we formulate a linear programming problem to compute the maximum throughput and show its superiority over one in networks without coding. Finally, the MMF problem in wireless network coding is shown to be NP-hard and a polynomial approximation algorithm is proposed.
The optical synthetic aperture image restoration based on the improved maximum-likelihood algorithm
Geng, Zexun; Xu, Qing; Zhang, Baoming; Gong, Zhihui
2012-09-01
Optical synthetic aperture imaging (OSAI) can be envisaged in the future for improving the image resolution from high altitude orbits. Several future projects are based on optical synthetic aperture for science or earth observation. Comparing with equivalent monolithic telescopes, however, the partly filled aperture of OSAI induces the attenuation of the modulation transfer function of the system. Consequently, images acquired by OSAI instrument have to be post-processed to restore ones equivalent in resolution to that of a single filled aperture. The maximum-likelihood (ML) algorithm proposed by Benvenuto performed better than traditional Wiener filter did, but it didn't work stably and the point spread function (PSF), was assumed to be known and unchanged in iterative restoration. In fact, the PSF is unknown in most cases, and its estimation was expected to be updated alternatively in optimization. Facing these limitations of this method, an improved ML (IML) reconstruction algorithm was proposed in this paper, which incorporated PSF estimation by means of parameter identification into ML, and updated the PSF successively during iteration. Accordingly, the IML algorithm converged stably and reached better results. Experiment results showed that the proposed algorithm performed much better than ML did in peak signal to noise ratio, mean square error and the average contrast evaluation indexes.
Improved Zernike-type phase contrast for transmission electron microscopy.
Koeck, P J B
2015-07-01
Zernike phase contrast has been recognized as a means of recording high-resolution images with high contrast using a transmission electron microscope. This imaging mode can be used to image typical phase objects such as unstained biological molecules or cryosections of biological tissue. According to the original proposal discussed in Danev and Nagayama (2001) and references therein, the Zernike phase plate applies a phase shift of π/2 to all scattered electron beams outside a given scattering angle and an image is recorded at Gaussian focus or slight underfocus (below Scherzer defocus). Alternatively, a phase shift of -π/2 is applied to the central beam using the Boersch phase plate. The resulting image will have an almost perfect contrast transfer function (close to 1) from a given lowest spatial frequency up to a maximum resolution determined by the wave length, the amount of defocus and the spherical aberration of the microscope. In this paper, I present theory and simulations showing that this maximum spatial frequency can be increased considerably without loss of contrast by using a Zernike or Boersch phase plate that leads to a phase shift between scattered and unscattered electrons of only π /4, and recording images at Scherzer defocus. The maximum resolution can be improved even more by imaging at extended Scherzer defocus, though at the cost of contrast loss at lower spatial frequencies. © 2015 The Authors Journal of Microscopy © 2015 Royal Microscopical Society.
Gadolinium nanoparticles and contrast agent as radiation sensitizers.
Taupin, Florence; Flaender, Mélanie; Delorme, Rachel; Brochard, Thierry; Mayol, Jean-François; Arnaud, Josiane; Perriat, Pascal; Sancey, Lucie; Lux, François; Barth, Rolf F; Carrière, Marie; Ravanat, Jean-Luc; Elleaume, Hélène
2015-06-01
The goal of the present study was to evaluate and compare the radiosensitizing properties of gadolinium nanoparticles (NPs) with the gadolinium contrast agent (GdCA) Magnevist(®) in order to better understand the mechanisms by which they act as radiation sensitizers. This was determined following either low energy synchrotron irradiation or high energy gamma irradiation of F98 rat glioma cells exposed to ultrasmall gadolinium NPs (GdNPs, hydrodynamic diameter of 3 nm) or GdCA. Clonogenic assays were used to quantify cell survival after irradiation in the presence of Gd using monochromatic x-rays with energies in the 25 keV-80 keV range from a synchrotron and 1.25 MeV gamma photons from a cobalt-60 source. Radiosensitization was demonstrated with both agents in combination with X-irradiation. At the same concentration (2.1 mg mL(-1)), GdNPS had a greater effect than GdCA. The maximum sensitization-enhancement ratio at 4 Gy (SER4Gy) was observed at an energy of 65 keV for both the nanoparticles and the contrast agent (2.44 ± 0.33 and 1.50 ± 0.20, for GdNPs and GdCA, respectively). At a higher energy (1.25 MeV), radiosensitization only was observed with GdNPs (1.66 ± 0.17 and 1.01 ± 0.11, for GdNPs and GdCA, respectively). The radiation dose enhancements were highly 'energy dependent' for both agents. Secondary-electron-emission generated after photoelectric events appeared to be the primary mechanism by which Gd contrast agents functioned as radiosensitizers. On the other hand, other biological mechanisms, such as alterations in the cell cycle may explain the enhanced radiosensitizing properties of GdNPs.
Nonlinear intravascular ultrasound contrast imaging
Goertz, David E.; Frijlink, Martijn E.; de Jong, N.; van der Steen, Antonius F.W.
2006-01-01
Nonlinear contrast agent imaging with intravascular ultrasound (IVUS) is investigated using a prototype IVUS system and an experimental small bubble contrast agent. The IVUS system employed a mechanically scanned single element transducer and was operated at a 20 MHz transmit frequency (F20) for
Contrast enhancement in light microscopy.
Ernst Keller, H; Watkins, Simon
2013-01-01
The optical microscope is a fundamental component of an image cytometry system. This unit covers the basic concepts of light microscopy, including Köhler illumination, resolution, contrast, and numerical aperture, and reviews the many types of instruments and techniques for contrast enhancement.
Contrast-enhanced peripheral MRA
Nielsen, Yousef W; Thomsen, Henrik S
2012-01-01
In the last decade contrast-enhanced magnetic resonance angiography (CE-MRA) has gained wide acceptance as a valuable tool in the diagnostic work-up of patients with peripheral arterial disease. This review presents current concepts in peripheral CE-MRA with emphasis on MRI technique and contrast...
The Wiener maximum quadratic assignment problem
Cela, Eranda; Woeginger, Gerhard J
2011-01-01
We investigate a special case of the maximum quadratic assignment problem where one matrix is a product matrix and the other matrix is the distance matrix of a one-dimensional point set. We show that this special case, which we call the Wiener maximum quadratic assignment problem, is NP-hard in the ordinary sense and solvable in pseudo-polynomial time. Our approach also yields a polynomial time solution for the following problem from chemical graph theory: Find a tree that maximizes the Wiener index among all trees with a prescribed degree sequence. This settles an open problem from the literature.
Maximum confidence measurements via probabilistic quantum cloning
Zhang Wen-Hai; Yu Long-Bao; Cao Zhuo-Liang; Ye Liu
2013-01-01
Probabilistic quantum cloning (PQC) cannot copy a set of linearly dependent quantum states.In this paper,we show that if incorrect copies are allowed to be produced,linearly dependent quantum states may also be cloned by the PQC.By exploiting this kind of PQC to clone a special set of three linearly dependent quantum states,we derive the upper bound of the maximum confidence measure of a set.An explicit transformation of the maximum confidence measure is presented.
Maximum floodflows in the conterminous United States
Crippen, John R.; Bue, Conrad D.
1977-01-01
Peak floodflows from thousands of observation sites within the conterminous United States were studied to provide a guide for estimating potential maximum floodflows. Data were selected from 883 sites with drainage areas of less than 10,000 square miles (25,900 square kilometers) and were grouped into regional sets. Outstanding floods for each region were plotted on graphs, and envelope curves were computed that offer reasonable limits for estimates of maximum floods. The curves indicate that floods may occur that are two to three times greater than those known for most streams.
Revealing the Maximum Strength in Nanotwinned Copper
Lu, L.; Chen, X.; Huang, Xiaoxu
2009-01-01
The strength of polycrystalline materials increases with decreasing grain size. Below a critical size, smaller grains might lead to softening, as suggested by atomistic simulations. The strongest size should arise at a transition in deformation mechanism from lattice dislocation activities to grain...... boundary–related processes. We investigated the maximum strength of nanotwinned copper samples with different twin thicknesses. We found that the strength increases with decreasing twin thickness, reaching a maximum at 15 nanometers, followed by a softening at smaller values that is accompanied by enhanced...
The Maximum Resource Bin Packing Problem
Boyar, J.; Epstein, L.; Favrholdt, L.M.
2006-01-01
Usually, for bin packing problems, we try to minimize the number of bins used or in the case of the dual bin packing problem, maximize the number or total size of accepted items. This paper presents results for the opposite problems, where we would like to maximize the number of bins used...... algorithms, First-Fit-Increasing and First-Fit-Decreasing for the maximum resource variant of classical bin packing. For the on-line variant, we define maximum resource variants of classical and dual bin packing. For dual bin packing, no on-line algorithm is competitive. For classical bin packing, we find...
Maximum entropy analysis of EGRET data
Pohl, M.; Strong, A.W.
1997-01-01
EGRET data are usually analysed on the basis of the Maximum-Likelihood method \\cite{ma96} in a search for point sources in excess to a model for the background radiation (e.g. \\cite{hu97}). This method depends strongly on the quality of the background model, and thus may have high systematic unce...... uncertainties in region of strong and uncertain background like the Galactic Center region. Here we show images of such regions obtained by the quantified Maximum-Entropy method. We also discuss a possible further use of MEM in the analysis of problematic regions of the sky....
Revealing the Maximum Strength in Nanotwinned Copper
Lu, L.; Chen, X.; Huang, Xiaoxu
2009-01-01
The strength of polycrystalline materials increases with decreasing grain size. Below a critical size, smaller grains might lead to softening, as suggested by atomistic simulations. The strongest size should arise at a transition in deformation mechanism from lattice dislocation activities to grain...... boundary–related processes. We investigated the maximum strength of nanotwinned copper samples with different twin thicknesses. We found that the strength increases with decreasing twin thickness, reaching a maximum at 15 nanometers, followed by a softening at smaller values that is accompanied by enhanced...
Maximum phytoplankton concentrations in the sea
Jackson, G.A.; Kiørboe, Thomas
2008-01-01
A simplification of plankton dynamics using coagulation theory provides predictions of the maximum algal concentration sustainable in aquatic systems. These predictions have previously been tested successfully against results from iron fertilization experiments. We extend the test to data collected...... in the North Atlantic as part of the Bermuda Atlantic Time Series program as well as data collected off Southern California as part of the Southern California Bight Study program. The observed maximum particulate organic carbon and volumetric particle concentrations are consistent with the predictions...
Envera Variable Compression Ratio Engine
Charles Mendler
2011-03-15
the compression ratio can be raised (to as much as 18:1) providing high engine efficiency. It is important to recognize that for a well designed VCR engine cylinder pressure does not need to be higher than found in current production turbocharged engines. As such, there is no need for a stronger crankcase, bearings and other load bearing parts within the VCR engine. The Envera VCR mechanism uses an eccentric carrier approach to adjust engine compression ratio. The crankshaft main bearings are mounted in this eccentric carrier or 'crankshaft cradle' and pivoting the eccentric carrier 30 degrees adjusts compression ratio from 9:1 to 18:1. The eccentric carrier is made up of a casting that provides rigid support for the main bearings, and removable upper bearing caps. Oil feed to the main bearings transits through the bearing cap fastener sockets. The eccentric carrier design was chosen for its low cost and rigid support of the main bearings. A control shaft and connecting links are used to pivot the eccentric carrier. The control shaft mechanism features compression ratio lock-up at minimum and maximum compression ratio settings. The control shaft method of pivoting the eccentric carrier was selected due to its lock-up capability. The control shaft can be rotated by a hydraulic actuator or an electric motor. The engine shown in Figures 3 and 4 has a hydraulic actuator that was developed under the current program. In-line 4-cylinder engines are significantly less expensive than V engines because an entire cylinder head can be eliminated. The cost savings from eliminating cylinders and an entire cylinder head will notably offset the added cost of the VCR and supercharging. Replacing V6 and V8 engines with in-line VCR 4-cylinder engines will provide high fuel economy at low cost. Numerous enabling technologies exist which have the potential to increase engine efficiency. The greatest efficiency gains are realized when the right combination of advanced and new
An Image-Domain Contrast Material Extraction Method for Dual-Energy Computed Tomography.
Lambert, Jack W; Sun, Yuxin; Gould, Robert G; Ohliger, Michael A; Li, Zhixi; Yeh, Benjamin M
2017-04-01
Conventional material decomposition techniques for dual-energy computed tomography (CT) assume mass or volume conservation, where the CT number of each voxel is fully assigned to predefined materials. We present an image-domain contrast material extraction process (CMEP) method that preferentially extracts contrast-producing materials while leaving the remaining image intact. Image processing freeware (Fiji) is used to perform consecutive arithmetic operations on a dual-energy ratio map to generate masks, which are then applied to the original images to generate material-specific images. First, a low-energy image is divided by a high-energy image to generate a ratio map. The ratio map is then split into material-specific masks. Ratio intervals known to correspond to particular materials (eg, iodine, calcium) are assigned a multiplier of 1, whereas ratio values in between these intervals are assigned linear gradients from 0 to 1. The masks are then multiplied by an original CT image to produce material-specific images. The method was tested quantitatively at dual-source CT and rapid kVp-switching CT (RSCT) with phantoms using pure and mixed formulations of tungsten, calcium, and iodine. Errors were evaluated by comparing the known material concentrations with those derived from the CMEP material-specific images. Further qualitative evaluation was performed in vivo at RSCT with a rabbit model using identical CMEP parameters to the phantom. Orally administered tungsten, vascularly administered iodine, and skeletal calcium were used as the 3 contrast materials. All 5 material combinations-tungsten, iodine, and calcium, and mixtures of tungsten-calcium and iodine-calcium-showed distinct dual-energy ratios, largely independent of material concentration at both dual-source CT and RSCT. The CMEP was successful in both phantoms and in vivo. For pure contrast materials in the phantom, the maximum error between the known and CMEP-derived material concentrations was 0.9 mg
Dependence of maximum concentration from chemical accidents on release duration
Hanna, Steven; Chang, Joseph
2017-01-01
Chemical accidents often involve releases of a total mass, Q, of stored material in a tank over a time duration, td, of less than a few minutes. The value of td is usually uncertain because of lack of knowledge of key information, such as the size and location of the hole and the pressure and temperature of the chemical. In addition, it is rare that eyewitnesses or video cameras are present at the time of the accident. For inhalation hazards, serious health effects (such as damage to the respiratory system) are determined by short term averages (pressurized liquefied chlorine releases from tanks are given, focusing on scenarios from the Jack Rabbit I (JR I) field experiment. The analytical calculations and the predictions of the SLAB dense gas dispersion model agree that the ratio of maximum C for two different td's is greatest (as much as a factor of ten) near the source. At large distances (beyond a few km for the JR I scenarios), where tt exceeds both td's, the ratio of maximum C approaches unity.
IDENTIFICATION OF IDEOTYPES BY CANONICAL ANALYSIS IN Panicum maximum
Janaina Azevedo Martuscello
2015-04-01
Full Text Available Grouping of genotypes by canonical variable analysis is an important tool in breeding. It allows the grouping of individuals with similar characteristics that are associated with superior agronomic performance and may indicate the ideal profile of a plant for the region. The objective of the present study was to define, by canonical analysis, the agronomic profile of Panicum maximum plants adapted to the Agreste region. The experiment was conducted in a completely randomized design with 28 treatments, 22 genotypes of Panicum maximum, and cultivars Mombasa, Tanzania, Massai, Milenio, BRS Zuri, and BRS Tamani in triplicate in 4-m² plots. Plots were harvested five times and the following traits were evaluated: plant height; total, leaf, and stem; dead dry matter yields; leaf:stem ratio; leaf percentage; and volumetric density of forage. The analysis of canonical variables was performed based on the phenotypic means of the evaluated traits and on the residual variance and covariance matrix. Genotype PM34 showed higher mean leaf dry matter yield under the conditions of the Agreste of Alagoas (on average 53% higher than cultivars Mombasa, Tanzania, Milenio and Massai. It was possible to summarize the variation observed in eight agronomic characteristics in only two canonical variables accounting for 81.44 % of the data variation. The ideotype plant adapted to the conditions of the Agreste should be tall and present high leaf yield, leaf percentage, and leaf:stem ratio, and intermediate values of volumetric density of forage.
Maximum tunneling velocities in symmetric double well potentials
Manz, Jörn [State Key Laboratory of Quantum Optics and Quantum Optics Devices, Institute of Laser Spectroscopy, Shanxi University, 92, Wucheng Road, Taiyuan 030006 (China); Institut für Chemie und Biochemie, Freie Universität Berlin, Takustr. 3, 14195 Berlin (Germany); Schild, Axel [Institut für Chemie und Biochemie, Freie Universität Berlin, Takustr. 3, 14195 Berlin (Germany); Schmidt, Burkhard, E-mail: burkhard.schmidt@fu-berlin.de [Institut für Mathematik, Freie Universität Berlin, Arnimallee 6, 14195 Berlin (Germany); Yang, Yonggang, E-mail: ygyang@sxu.edu.cn [State Key Laboratory of Quantum Optics and Quantum Optics Devices, Institute of Laser Spectroscopy, Shanxi University, 92, Wucheng Road, Taiyuan 030006 (China)
2014-10-17
Highlights: • Coherent tunneling in one-dimensional symmetric double well potentials. • Potentials for analytical estimates in the deep tunneling regime. • Maximum velocities scale as the square root of the ratio of barrier height and mass. • In chemical physics maximum tunneling velocities are in the order of a few km/s. - Abstract: We consider coherent tunneling of one-dimensional model systems in non-cyclic or cyclic symmetric double well potentials. Generic potentials are constructed which allow for analytical estimates of the quantum dynamics in the non-relativistic deep tunneling regime, in terms of the tunneling distance, barrier height and mass (or moment of inertia). For cyclic systems, the results may be scaled to agree well with periodic potentials for which semi-analytical results in terms of Mathieu functions exist. Starting from a wavepacket which is initially localized in one of the potential wells, the subsequent periodic tunneling is associated with tunneling velocities. These velocities (or angular velocities) are evaluated as the ratio of the flux densities versus the probability densities. The maximum velocities are found under the top of the barrier where they scale as the square root of the ratio of barrier height and mass (or moment of inertia), independent of the tunneling distance. They are applied exemplarily to several prototypical molecular models of non-cyclic and cyclic tunneling, including ammonia inversion, Cope rearrangement of semibullvalene, torsions of molecular fragments, and rotational tunneling in strong laser fields. Typical maximum velocities and angular velocities are in the order of a few km/s and from 10 to 100 THz for our non-cyclic and cyclic systems, respectively, much faster than time-averaged velocities. Even for the more extreme case of an electron tunneling through a barrier of height of one Hartree, the velocity is only about one percent of the speed of light. Estimates of the corresponding time scales for
On maximum cycle packings in polyhedral graphs
Peter Recht
2014-04-01
Full Text Available This paper addresses upper and lower bounds for the cardinality of a maximum vertex-/edge-disjoint cycle packing in a polyhedral graph G. Bounds on the cardinality of such packings are provided, that depend on the size, the order or the number of faces of G, respectively. Polyhedral graphs are constructed, that attain these bounds.
Hard graphs for the maximum clique problem
Hoede, Cornelis
1988-01-01
The maximum clique problem is one of the NP-complete problems. There are graphs for which a reduction technique exists that transforms the problem for these graphs into one for graphs with specific properties in polynomial time. The resulting graphs do not grow exponentially in order and number. Gra
Maximum Likelihood Estimation of Search Costs
J.L. Moraga-Gonzalez (José Luis); M.R. Wildenbeest (Matthijs)
2006-01-01
textabstractIn a recent paper Hong and Shum (forthcoming) present a structural methodology to estimate search cost distributions. We extend their approach to the case of oligopoly and present a maximum likelihood estimate of the search cost distribution. We apply our method to a data set of online p
Weak Scale From the Maximum Entropy Principle
Hamada, Yuta; Kawana, Kiyoharu
2015-01-01
The theory of multiverse and wormholes suggests that the parameters of the Standard Model are fixed in such a way that the radiation of the $S^{3}$ universe at the final stage $S_{rad}$ becomes maximum, which we call the maximum entropy principle. Although it is difficult to confirm this principle generally, for a few parameters of the Standard Model, we can check whether $S_{rad}$ actually becomes maximum at the observed values. In this paper, we regard $S_{rad}$ at the final stage as a function of the weak scale ( the Higgs expectation value ) $v_{h}$, and show that it becomes maximum around $v_{h}={\\cal{O}}(300\\text{GeV})$ when the dimensionless couplings in the Standard Model, that is, the Higgs self coupling, the gauge couplings, and the Yukawa couplings are fixed. Roughly speaking, we find that the weak scale is given by \\begin{equation} v_{h}\\sim\\frac{T_{BBN}^{2}}{M_{pl}y_{e}^{5}},\
Weak scale from the maximum entropy principle
Hamada, Yuta; Kawai, Hikaru; Kawana, Kiyoharu
2015-03-01
The theory of the multiverse and wormholes suggests that the parameters of the Standard Model (SM) are fixed in such a way that the radiation of the S3 universe at the final stage S_rad becomes maximum, which we call the maximum entropy principle. Although it is difficult to confirm this principle generally, for a few parameters of the SM, we can check whether S_rad actually becomes maximum at the observed values. In this paper, we regard S_rad at the final stage as a function of the weak scale (the Higgs expectation value) vh, and show that it becomes maximum around vh = {{O}} (300 GeV) when the dimensionless couplings in the SM, i.e., the Higgs self-coupling, the gauge couplings, and the Yukawa couplings are fixed. Roughly speaking, we find that the weak scale is given by vh ˜ T_{BBN}2 / (M_{pl}ye5), where ye is the Yukawa coupling of electron, T_BBN is the temperature at which the Big Bang nucleosynthesis starts, and M_pl is the Planck mass.
Global characterization of the Holocene Thermal Maximum
Renssen, H.; Seppä, H.; Crosta, X.; Goosse, H.; Roche, D.M.V.A.P.
2012-01-01
We analyze the global variations in the timing and magnitude of the Holocene Thermal Maximum (HTM) and their dependence on various forcings in transient simulations covering the last 9000 years (9 ka), performed with a global atmosphere-ocean-vegetation model. In these experiments, we consider the i
Instance Optimality of the Adaptive Maximum Strategy
L. Diening; C. Kreuzer; R. Stevenson
2016-01-01
In this paper, we prove that the standard adaptive finite element method with a (modified) maximum marking strategy is instance optimal for the total error, being the square root of the squared energy error plus the squared oscillation. This result will be derived in the model setting of Poisson’s e
Maximum phonation time: variability and reliability.
Speyer, Renée; Bogaardt, Hans C A; Passos, Valéria Lima; Roodenburg, Nel P H D; Zumach, Anne; Heijnen, Mariëlle A M; Baijens, Laura W J; Fleskens, Stijn J H M; Brunings, Jan W
2010-05-01
The objective of the study was to determine maximum phonation time reliability as a function of the number of trials, days, and raters in dysphonic and control subjects. Two groups of adult subjects participated in this reliability study: a group of outpatients with functional or organic dysphonia versus a group of healthy control subjects matched by age and gender. Over a period of maximally 6 weeks, three video recordings were made of five subjects' maximum phonation time trials. A panel of five experts were responsible for all measurements, including a repeated measurement of the subjects' first recordings. Patients showed significantly shorter maximum phonation times compared with healthy controls (on average, 6.6 seconds shorter). The averaged interclass correlation coefficient (ICC) over all raters per trial for the first day was 0.998. The averaged reliability coefficient per rater and per trial for repeated measurements of the first day's data was 0.997, indicating high intrarater reliability. The mean reliability coefficient per day for one trial was 0.939. When using five trials, the reliability increased to 0.987. The reliability over five trials for a single day was 0.836; for 2 days, 0.911; and for 3 days, 0.935. To conclude, the maximum phonation time has proven to be a highly reliable measure in voice assessment. A single rater is sufficient to provide highly reliable measurements.
Maximum Phonation Time: Variability and Reliability
R. Speyer; H.C.A. Bogaardt; V.L. Passos; N.P.H.D. Roodenburg; A. Zumach; M.A.M. Heijnen; L.W.J. Baijens; S.J.H.M. Fleskens; J.W. Brunings
2010-01-01
The objective of the study was to determine maximum phonation time reliability as a function of the number of trials, days, and raters in dysphonic and control subjects. Two groups of adult subjects participated in this reliability study: a group of outpatients with functional or organic dysphonia v
Maximum likelihood estimation of fractionally cointegrated systems
Lasak, Katarzyna
In this paper we consider a fractionally cointegrated error correction model and investigate asymptotic properties of the maximum likelihood (ML) estimators of the matrix of the cointe- gration relations, the degree of fractional cointegration, the matrix of the speed of adjustment...
Maximum likelihood estimation for integrated diffusion processes
Baltazar-Larios, Fernando; Sørensen, Michael
EM-algorithm to obtain maximum likelihood estimates of the parameters in the diffusion model. As part of the algorithm, we use a recent simple method for approximate simulation of diffusion bridges. In simulation studies for the Ornstein-Uhlenbeck process and the CIR process the proposed method works...
Maximum gain of Yagi-Uda arrays
Bojsen, J.H.; Schjær-Jacobsen, Hans; Nilsson, E.
1971-01-01
Numerical optimisation techniques have been used to find the maximum gain of some specific parasitic arrays. The gain of an array of infinitely thin, equispaced dipoles loaded with arbitrary reactances has been optimised. The results show that standard travelling-wave design methods are not optimum....... Yagi–Uda arrays with equal and unequal spacing have also been optimised with experimental verification....
Contrast-enhanced peripheral MRA. Technique and contrast agents
Nielsen, Yousef W. [Dept. of Radiology, Copenhagen Univ. Hospital Bispebjerg, Bispebjerg (Denmark)], e-mail: ywnielsen@gmail.com; Thomsen, Henrik S. [Dept. of Diagnostic Radiology, Copenhagen Univ. Hospital Herlev, Herlev (Denmark)
2012-09-15
In the last decade contrast-enhanced magnetic resonance angiography (CE-MRA) has gained wide acceptance as a valuable tool in the diagnostic work-up of patients with peripheral arterial disease. This review presents current concepts in peripheral CE-MRA with emphasis on MRI technique and contrast agents. Peripheral CE-MRA is defined as an MR angiogram of the arteries from the aortic bifurcation to the feet. Advantages of CE-MRA include minimal invasiveness and lack of ionizing radiation. The basic technique employed for peripheral CE-MRA is the bolus-chase method. With this method a paramagnetic MRI contrast agent is injected intravenously and T1-weighted images are acquired in the subsequent arterial first-pass phase. In order to achieve high quality MR angiograms without interfering venous contamination or artifacts, a number of factors need to be taken into account. This includes magnetic field strength of the MRI system, receiver coil configuration, use of parallel imaging, contrast bolus timing technique, and k-space filling strategies. Furthermore, it is possible to optimize peripheral CE-MRA using venous compression techniques, hybrid scan protocols, time-resolved imaging, and steady-state MRA. Gadolinium(Gd)-based contrast agents are used for CE-MRA of the peripheral arteries. Extracellular Gd agents have a pharmacokinetic profile similar to iodinated contrast media. Accordingly, these agents are employed for first-pass MRA. Blood-pool Gd-based agents are characterized by prolonged intravascular stay, due to macromolecular structure or protein binding. These agents can be used for first-pass, as well as steady-state MRA. Some Gd-based contrast agents with low thermodynamic stability have been linked to development of nephrogenic systemic fibrosis in patients with severe renal insufficiency. Using optimized technique and a stable MRI contrast agent, peripheral CE-MRA is a safe procedure with diagnostic accuracy close to that of conventional catheter X
Buskulic, Damir; De Bonis, I; Décamp, D; Ghez, P; Goy, C; Lees, J P; Lucotte, A; Minard, M N; Odier, P; Pietrzyk, B; Ariztizabal, F; Chmeissani, M; Crespo, J M; Efthymiopoulos, I; Fernández, E; Fernández-Bosman, M; Gaitan, V; Martínez, M; Orteu, S; Pacheco, A; Padilla, C; Palla, Fabrizio; Pascual, A; Perlas, J A; Sánchez, F; Teubert, F; Colaleo, A; Creanza, D; De Palma, M; Farilla, A; Gelao, G; Girone, M; Iaselli, Giuseppe; Maggi, G; Maggi, M; Marinelli, N; Natali, S; Nuzzo, S; Ranieri, A; Raso, G; Romano, F; Ruggieri, F; Selvaggi, G; Silvestris, L; Tempesta, P; Zito, G; Huang, X; Lin, J; Ouyang, Q; Wang, T; Xie, Y; Xu, R; Xue, S; Zhang, J; Zhang, L; Zhao, W; Bonvicini, G; Cattaneo, M; Comas, P; Coyle, P; Drevermann, H; Engelhardt, A; Forty, Roger W; Frank, M; Hagelberg, R; Harvey, J; Jacobsen, R; Janot, P; Jost, B; Kneringer, E; Knobloch, J; Lehraus, Ivan; Markou, C; Martin, E B; Mato, P; Minten, Adolf G; Miquel, R; Oest, T; Palazzi, P; Pater, J R; Pusztaszeri, J F; Ranjard, F; Rensing, P E; Rolandi, Luigi; Schlatter, W D; Schmelling, M; Schneider, O; Tejessy, W; Tomalin, I R; Venturi, A; Wachsmuth, H W; Wiedenmann, W; Wildish, T; Witzeling, W; Wotschack, J; Ajaltouni, Ziad J; Bardadin-Otwinowska, Maria; Barrès, A; Boyer, C; Falvard, A; Gay, P; Guicheney, C; Henrard, P; Jousset, J; Michel, B; Monteil, S; Pallin, D; Perret, P; Podlyski, F; Proriol, J; Rossignol, J M; Saadi, F; Fearnley, Tom; Hansen, J B; Hansen, J D; Hansen, J R; Hansen, P H; Nilsson, B S; Kyriakis, A; Simopoulou, Errietta; Siotis, I; Vayaki, Anna; Zachariadou, K; Blondel, A; Bonneaud, G R; Brient, J C; Bourdon, P; Passalacqua, L; Rougé, A; Rumpf, M; Tanaka, R; Valassi, Andrea; Verderi, M; Videau, H L; Candlin, D J; Parsons, M I; Focardi, E; Parrini, G; Corden, M; Delfino, M C; Georgiopoulos, C H; Jaffe, D E; Antonelli, A; Bencivenni, G; Bologna, G; Bossi, F; Campana, P; Capon, G; Chiarella, V; Felici, G; Laurelli, P; Mannocchi, G; Murtas, F; Murtas, G P; Pepé-Altarelli, M; Dorris, S J; Halley, A W; ten Have, I; Knowles, I G; Lynch, J G; Morton, W T; O'Shea, V; Raine, C; Reeves, P; Scarr, J M; Smith, K; Smith, M G; Thompson, A S; Thomson, F; Thorn, S; Turnbull, R M; Becker, U; Braun, O; Geweniger, C; Graefe, G; Hanke, P; Hepp, V; Kluge, E E; Putzer, A; Rensch, B; Schmidt, M; Sommer, J; Stenzel, H; Tittel, K; Werner, S; Wunsch, M; Beuselinck, R; Binnie, David M; Cameron, W; Colling, D J; Dornan, Peter J; Konstantinidis, N P; Moneta, L; Moutoussi, A; Nash, J; San Martin, G; Sedgbeer, J K; Stacey, A M; Dissertori, G; Girtler, P; Kuhn, D; Rudolph, G; Bowdery, C K; Brodbeck, T J; Colrain, P; Crawford, G; Finch, A J; Foster, F; Hughes, G; Sloan, Terence; Whelan, E P; Williams, M I; Galla, A; Greene, A M; Kleinknecht, K; Quast, G; Raab, J; Renk, B; Sander, H G; Wanke, R; Van Gemmeren, P; Zeitnitz, C; Aubert, Jean-Jacques; Bencheikh, A M; Benchouk, C; Bonissent, A; Bujosa, G; Calvet, D; Carr, J; Diaconu, C A; Etienne, F; Thulasidas, M; Nicod, D; Payre, P; Rousseau, D; Talby, M; Abt, I; Assmann, R W; Bauer, C; Blum, Walter; Brown, D; Dietl, H; Dydak, Friedrich; Ganis, G; Gotzhein, C; Jakobs, K; Kroha, H; Lütjens, G; Lutz, Gerhard; Männer, W; Moser, H G; Richter, R H; Rosado-Schlosser, A; Schael, S; Settles, Ronald; Seywerd, H C J; Saint-Denis, R; Wolf, G; Alemany, R; Boucrot, J; Callot, O; Cordier, A; Courault, F; Davier, M; Duflot, L; Grivaz, J F; Heusse, P; Jacquet, M; Kim, D W; Le Diberder, F R; Lefrançois, J; Lutz, A M; Musolino, G; Nikolic, I A; Park, H J; Park, I C; Schune, M H; Simion, S; Veillet, J J; Videau, I; Abbaneo, D; Azzurri, P; Bagliesi, G; Batignani, G; Bettarini, S; Bozzi, C; Calderini, G; Carpinelli, M; Ciocci, M A; Ciulli, V; Dell'Orso, R; Fantechi, R; Ferrante, I; Foà, L; Forti, F; Giassi, A; Giorgi, M A; Gregorio, A; Ligabue, F; Lusiani, A; Marrocchesi, P S; Messineo, A; Rizzo, G; Sanguinetti, G; Sciabà, A; Spagnolo, P; Steinberger, Jack; Tenchini, Roberto; Tonelli, G; Triggiani, G; Vannini, C; Verdini, P G; Walsh, J; Betteridge, A P; Blair, G A; Bryant, L M; Cerutti, F; Gao, Y; Green, M G; Johnson, D L; Medcalf, T; Mir, L M; Perrodo, P; Strong, J A; Bertin, V; Botterill, David R; Clifft, R W; Edgecock, T R; Haywood, S; Edwards, M; Maley, P; Norton, P R; Thompson, J C; Bloch-Devaux, B; Colas, P; Emery, S; Kozanecki, Witold; Lançon, E; Lemaire, M C; Locci, E; Marx, B; Pérez, P; Rander, J; Renardy, J F; Roussarie, A; Schuller, J P; Schwindling, J; Trabelsi, A; Vallage, B; Johnson, R P; Kim, H Y; Litke, A M; McNeil, M A; Taylor, G; Beddall, A; Booth, C N; Boswell, R; Cartwright, S L; Combley, F; Dawson, I; Köksal, A; Letho, M; Newton, W M; Rankin, C; Thompson, L F; Böhrer, A; Brandt, S; Cowan, G D; Feigl, E; Grupen, Claus; Lutters, G; Minguet-Rodríguez, J A; Rivera, F; Saraiva, P; Smolik, L; Stephan, F; Apollonio, M; Bosisio, L; Della Marina, R; Giannini, G; Gobbo, B; Ragusa, F; Rothberg, J E; Wasserbaech, S R; Armstrong, S R; Bellantoni, L; Elmer, P; Feng, Z; Ferguson, D P S; Gao, Y S; González, S; Grahl, J; Harton, J L; Hayes, O J; Hu, H; McNamara, P A; Nachtman, J M; Orejudos, W; Pan, Y B; Saadi, Y; Schmitt, M; Scott, I J; Sharma, V; Turk, J; Walsh, A M; Wu Sau Lan; Wu, X; Yamartino, J M; Zheng, M; Zobernig, G
1996-01-01
From 64492 selected \\tau-pair events, produced at the Z^0 resonance, the measurement of the tau decays into hadrons from a global analysis using 1991, 1992 and 1993 ALEPH data is presented. Special emphasis is given to the reconstruction of photons and \\pi^0's, and the removal of fake photons. A detailed study of the systematics entering the \\pi^0 reconstruction is also given. A complete and consistent set of tau hadronic branching ratios is presented for 18 exclusive modes. Most measurements are more precise than the present world average. The new level of precision reached allows a stringent test of \\tau-\\mu universality in hadronic decays, g_\\tau/g_\\mu \\ = \\ 1.0013 \\ \\pm \\ 0.0095, and the first measurement of the vector and axial-vector contributions to the non-strange hadronic \\tau decay width: R_{\\tau ,V} \\ = \\ 1.788 \\ \\pm \\ 0.025 and R_{\\tau ,A} \\ = \\ 1.694 \\ \\pm \\ 0.027. The ratio (R_{\\tau ,V} - R_{\\tau ,A}) / (R_{\\tau ,V} + R_{\\tau ,A}), equal to (2.7 \\pm 1.3) \\ \\%, is a measure of the importance of Q...
Improved Hilbert phase contrast for transmission electron microscopy
Koeck, Philip J.B.
2015-07-15
Hilbert phase contrast has been recognized as a means of recording high resolution images with high contrast using a transmission electron microscope. This imaging mode could be used to image typical phase objects such as unstained biological molecules or cryo sections of biological tissue. According to the original proposal by (Danev et al., 2002) the Hilbert phase plate applies a phase shift of π to approximately half the focal plane (for example the right half excluding the central beam) and an image is recorded at Gaussian focus. After correction for the inbuilt asymmetry of differential phase contrast this image will have an almost perfect contrast transfer function (close to 1) from the lowest spatial frequency up to a maximum resolution determined by the wave length and spherical aberration of the microscope. In this paper I present theory and simulations showing that this maximum spatial frequency can be increased considerably almost without loss of contrast by using a Hilbert phase plate of half the thickness, leading to a phase shift of π/2, and recording images at Scherzer defocus. The maximum resolution can be improved even more by imaging at extended Scherzer defocus, though at the cost of contrast loss at lower spatial frequencies. - Highlights: • In this paper I present theory and simulations for a Hilbert phase plate that phase shifts the electron wave by π/2 instead of π while images are recorded close to Scherzer defocus instead of Gaussian focus. • I show that the point resolution for this new imaging mode is considerably higher without loss of contrast. • An additional advantage lies in the reduced thickness of the phase plate which leads to reduced inelastic scattering in the phase plate and less noise.
Color Image Enhancement Based on Maximum Fuzzy Entropy
QU Yi; XU Li-hong; KANG Qi
2004-01-01
A color image enhancement approach based on maximum fuzzy entropy and genetic algorithm is proposed in this paper. It enhances color images by stretching the contrast of S and I components respectively in the HSI color representation. The image is transformed from the property domain to the fuzzy domain with S-function. To preserve as much information as possible in the fuzzy the domain, the fuzzy entropy function is used as objective function in a genetic algorithm to optimize three parameters of the S-function. The Sigmoid function is applied to intensify the membership values and the results are transformed back to the property domain to produce the enhanced image. Experiments show the effectiveness of the approach.
Adaptive edge image enhancement based on maximum fuzzy entropy
ZHANG Xiu-hua; YANG Kun-tao
2006-01-01
Based on the maximum fuzzy entropy principle,the edge image with low contrast is optimally classified into two classes adaptively,under the condition of probability partition and fuzzy partition.The optimal threshold is used as the classified threshold value,and a local parametric gray-level transformation is applied to the obtained classes.By means of two parameters representing,the homogeneity of the regions in edge image is improved.The excellent performance of the proposed technique is exercisable through simulation results on a set of test images.It is shown how the extracted and enhanced edges provide an efficient edge-representation of images.It is shown that the proposed technique possesses excellent performance in homogeneity through simulations on a set of test images,and the extracted and enhanced edges provide an efficient edge-representation of images.
Rainfall Maximum Intensities for Urban Hydrological Design in Mexican Republic
Campos–Aranda D.F.
2010-04-01
Full Text Available Firstly, through the urban hydrosystem concept and through urbanization, the difficulties and approach of the urban flood estimation are established, based in the Intensity–Duration–Frequency curves (IDF. Next, in 10 recording gages located in very different geographic zones, a procedure is contrasted for IDF estimation curves, which utilized the Chen formula and the available information in the Mexican Republic for isohyet intensities and annual daily maximum rainfall. Late, having verified their capacity and approximation to reproduce the IDF curves, the utilized procedure was applied in 45 important locations of the country, showing the results. Lastly, the conclusions are formulated, which point out the approximation and simplicity of the proposal procedure.
Maximum bandwidth snapshot channeled imaging polarimeter with polarization gratings
LaCasse, Charles F.; Redman, Brian J.; Kudenov, Michael W.; Craven, Julia M.
2016-05-01
Compact snapshot imaging polarimeters have been demonstrated in literature to provide Stokes parameter estimations for spatially varying scenes using polarization gratings. However, the demonstrated system does not employ aggressive modulation frequencies to take full advantage of the bandwidth available to the focal plane array. A snapshot imaging Stokes polarimeter is described and demonstrated through results. The simulation studies the challenges of using a maximum bandwidth configuration for a snapshot polarization grating based polarimeter, such as the fringe contrast attenuation that results from higher modulation frequencies. Similar simulation results are generated and compared for a microgrid polarimeter. Microgrid polarimeters are instruments where pixelated polarizers are superimposed onto a focal plan array, and this is another type of spatially modulated polarimeter, and the most common design uses a 2x2 super pixel of polarizers which maximally uses the available bandwidth of the focal plane array.
Small intestine contrast injection (image)
... and throat, through the stomach into the small intestine. When in place, contrast dye is introduced and ... means of demonstrating whether or not the small intestine is normal when abnormality is suspected.
Majority rule has transition ratio 4 on Yule trees under a 2-state symmetric model.
Mossel, Elchanan; Steel, Mike
2014-11-01
Inferring the ancestral state at the root of a phylogenetic tree from states observed at the leaves is a problem arising in evolutionary biology. The simplest technique - majority rule - estimates the root state by the most frequently occurring state at the leaves. Alternative methods - such as maximum parsimony - explicitly take the tree structure into account. Since either method can outperform the other on particular trees, it is useful to consider the accuracy of the methods on trees generated under some evolutionary null model, such as a Yule pure-birth model. In this short note, we answer a recently posed question concerning the performance of majority rule on Yule trees under a symmetric 2-state Markovian substitution model of character state change. We show that majority rule is accurate precisely when the ratio of the birth (speciation) rate of the Yule process to the substitution rate exceeds the value 4. By contrast, maximum parsimony has been shown to be accurate only when this ratio is at least 6. Our proof relies on a second moment calculation, coupling, and a novel application of a reflection principle.
Contrast-enhanced endoscopic ultrasonography
Nischita K Reddy; Ana Maria Ioncic(a); Adrian S(a)ftoiu; Peter Vilmann; Manoop S Bhutani
2011-01-01
Contrast agents are increasingly being used to characterize the vasculature in an organ of interest,to better delineate benign from malignant pathology and to aid in staging and directing therapeutic procedures.We review the mechanisms of action of first,second and third generation contrast agents and their use in various endoscopic procedures in the gastrointestinal tract.Various applications of contrast-enhanced endoscopic ultrasonography include differentiating benign from malignant mediastinal lymphadenopathy,assessment of depth of invasion of esophageal,gastric and gall bladder cancers and visualization of the portal venous system and esophageal varices.In addition,contrast agents can be used to differentiate pancreatic lesions.The use of color Doppler further increases the ability to diagnose and differentiate various pancreatic malignancies.The sensitivity of power Doppler sonography to depict tumor neovascularization can be increased by contrast agents.Contrast-enhanced harmonic imaging is a useful aid in identifying the tumor vasculature and studying pancreatic microperfusion.In the future,these techniques could potentially be used to quantify tumor perfusion,to assess and monitor the efficacy of antiangiogenic agents,to assist targeted drug delivery and allow molecular imaging.
A theory of behavioral contrast.
Killeen, Peter R
2014-11-01
The reinforcers that maintain target instrumental responses also reinforce other responses that compete with them for expression. This competition, and its imbalance at points of transition between different schedules of reinforcement, causes behavioral contrast. The imbalance is caused by differences in the rates at which different responses come under the control of component stimuli. A model for this theory of behavioral contrast is constructed by expanding the coupling coefficient of MPR (Killeen, 1994). The coupling coefficient gives the degree of association of a reinforcer with the target response (as opposed to other competing responses). Competing responses, often identified as interim or adjunctive or superstitious behavior, are intrinsic to reinforcement schedules, especially interval schedules. In addition to that base-rate of competition, additional competing responses may spill over from the prior component, causing initial contrast; and they may be modulated by conditioned reinforcement or punishment from stimuli associated with subsequent component change, causing terminal contrast. A formalization of these hypotheses employed (a) a hysteresis model of off-target responses giving rise to initial contrast, and (b) a competing traces model of the suppression or enhancement of ongoing competitive responses by signals of following-schedule transition. The theory was applied to transient contrast, the following schedule effect, and the component duration effect.
Model Selection Through Sparse Maximum Likelihood Estimation
Banerjee, Onureena; D'Aspremont, Alexandre
2007-01-01
We consider the problem of estimating the parameters of a Gaussian or binary distribution in such a way that the resulting undirected graphical model is sparse. Our approach is to solve a maximum likelihood problem with an added l_1-norm penalty term. The problem as formulated is convex but the memory requirements and complexity of existing interior point methods are prohibitive for problems with more than tens of nodes. We present two new algorithms for solving problems with at least a thousand nodes in the Gaussian case. Our first algorithm uses block coordinate descent, and can be interpreted as recursive l_1-norm penalized regression. Our second algorithm, based on Nesterov's first order method, yields a complexity estimate with a better dependence on problem size than existing interior point methods. Using a log determinant relaxation of the log partition function (Wainwright & Jordan (2006)), we show that these same algorithms can be used to solve an approximate sparse maximum likelihood problem for...
Maximum-entropy description of animal movement.
Fleming, Chris H; Subaşı, Yiğit; Calabrese, Justin M
2015-03-01
We introduce a class of maximum-entropy states that naturally includes within it all of the major continuous-time stochastic processes that have been applied to animal movement, including Brownian motion, Ornstein-Uhlenbeck motion, integrated Ornstein-Uhlenbeck motion, a recently discovered hybrid of the previous models, and a new model that describes central-place foraging. We are also able to predict a further hierarchy of new models that will emerge as data quality improves to better resolve the underlying continuity of animal movement. Finally, we also show that Langevin equations must obey a fluctuation-dissipation theorem to generate processes that fall from this class of maximum-entropy distributions when the constraints are purely kinematic.
Pareto versus lognormal: a maximum entropy test.
Bee, Marco; Riccaboni, Massimo; Schiavo, Stefano
2011-08-01
It is commonly found that distributions that seem to be lognormal over a broad range change to a power-law (Pareto) distribution for the last few percentiles. The distributions of many physical, natural, and social events (earthquake size, species abundance, income and wealth, as well as file, city, and firm sizes) display this structure. We present a test for the occurrence of power-law tails in statistical distributions based on maximum entropy. This methodology allows one to identify the true data-generating processes even in the case when it is neither lognormal nor Pareto. The maximum entropy approach is then compared with other widely used methods and applied to different levels of aggregation of complex systems. Our results provide support for the theory that distributions with lognormal body and Pareto tail can be generated as mixtures of lognormally distributed units.
Maximum Variance Hashing via Column Generation
Lei Luo
2013-01-01
item search. Recently, a number of data-dependent methods have been developed, reflecting the great potential of learning for hashing. Inspired by the classic nonlinear dimensionality reduction algorithm—maximum variance unfolding, we propose a novel unsupervised hashing method, named maximum variance hashing, in this work. The idea is to maximize the total variance of the hash codes while preserving the local structure of the training data. To solve the derived optimization problem, we propose a column generation algorithm, which directly learns the binary-valued hash functions. We then extend it using anchor graphs to reduce the computational cost. Experiments on large-scale image datasets demonstrate that the proposed method outperforms state-of-the-art hashing methods in many cases.
Nonparametric Maximum Entropy Estimation on Information Diagrams
Martin, Elliot A; Meinke, Alexander; Děchtěrenko, Filip; Davidsen, Jörn
2016-01-01
Maximum entropy estimation is of broad interest for inferring properties of systems across many different disciplines. In this work, we significantly extend a technique we previously introduced for estimating the maximum entropy of a set of random discrete variables when conditioning on bivariate mutual informations and univariate entropies. Specifically, we show how to apply the concept to continuous random variables and vastly expand the types of information-theoretic quantities one can condition on. This allows us to establish a number of significant advantages of our approach over existing ones. Not only does our method perform favorably in the undersampled regime, where existing methods fail, but it also can be dramatically less computationally expensive as the cardinality of the variables increases. In addition, we propose a nonparametric formulation of connected informations and give an illustrative example showing how this agrees with the existing parametric formulation in cases of interest. We furthe...
Zipf's law, power laws and maximum entropy
Visser, Matt
2013-04-01
Zipf's law, and power laws in general, have attracted and continue to attract considerable attention in a wide variety of disciplines—from astronomy to demographics to software structure to economics to linguistics to zoology, and even warfare. A recent model of random group formation (RGF) attempts a general explanation of such phenomena based on Jaynes' notion of maximum entropy applied to a particular choice of cost function. In the present paper I argue that the specific cost function used in the RGF model is in fact unnecessarily complicated, and that power laws can be obtained in a much simpler way by applying maximum entropy ideas directly to the Shannon entropy subject only to a single constraint: that the average of the logarithm of the observable quantity is specified.
Zipf's law, power laws, and maximum entropy
Visser, Matt
2012-01-01
Zipf's law, and power laws in general, have attracted and continue to attract considerable attention in a wide variety of disciplines - from astronomy to demographics to economics to linguistics to zoology, and even warfare. A recent model of random group formation [RGF] attempts a general explanation of such phenomena based on Jaynes' notion of maximum entropy applied to a particular choice of cost function. In the present article I argue that the cost function used in the RGF model is in fact unnecessarily complicated, and that power laws can be obtained in a much simpler way by applying maximum entropy ideas directly to the Shannon entropy subject only to a single constraint: that the average of the logarithm of the observable quantity is specified.
Regions of constrained maximum likelihood parameter identifiability
Lee, C.-H.; Herget, C. J.
1975-01-01
This paper considers the parameter identification problem of general discrete-time, nonlinear, multiple-input/multiple-output dynamic systems with Gaussian-white distributed measurement errors. Knowledge of the system parameterization is assumed to be known. Regions of constrained maximum likelihood (CML) parameter identifiability are established. A computation procedure employing interval arithmetic is proposed for finding explicit regions of parameter identifiability for the case of linear systems. It is shown that if the vector of true parameters is locally CML identifiable, then with probability one, the vector of true parameters is a unique maximal point of the maximum likelihood function in the region of parameter identifiability and the CML estimation sequence will converge to the true parameters.
Maximum Profit Configurations of Commercial Engines
Yiran Chen
2011-01-01
An investigation of commercial engines with finite capacity low- and high-price economic subsystems and a generalized commodity transfer law [n ∝ Δ (P m)] in commodity flow processes, in which effects of the price elasticities of supply and demand are introduced, is presented in this paper. Optimal cycle configurations of commercial engines for maximum profit are obtained by applying optimal control theory. In some special cases, the eventual state—market equilibrium—is solely determined by t...
A stochastic maximum principle via Malliavin calculus
Øksendal, Bernt; Zhou, Xun Yu; Meyer-Brandis, Thilo
2008-01-01
This paper considers a controlled It\\^o-L\\'evy process where the information available to the controller is possibly less than the overall information. All the system coefficients and the objective performance functional are allowed to be random, possibly non-Markovian. Malliavin calculus is employed to derive a maximum principle for the optimal control of such a system where the adjoint process is explicitly expressed.
Tissue radiation response with maximum Tsallis entropy.
Sotolongo-Grau, O; Rodríguez-Pérez, D; Antoranz, J C; Sotolongo-Costa, Oscar
2010-10-08
The expression of survival factors for radiation damaged cells is currently based on probabilistic assumptions and experimentally fitted for each tumor, radiation, and conditions. Here, we show how the simplest of these radiobiological models can be derived from the maximum entropy principle of the classical Boltzmann-Gibbs expression. We extend this derivation using the Tsallis entropy and a cutoff hypothesis, motivated by clinical observations. The obtained expression shows a remarkable agreement with the experimental data found in the literature.
Maximum Estrada Index of Bicyclic Graphs
Wang, Long; Wang, Yi
2012-01-01
Let $G$ be a simple graph of order $n$, let $\\lambda_1(G),\\lambda_2(G),...,\\lambda_n(G)$ be the eigenvalues of the adjacency matrix of $G$. The Esrada index of $G$ is defined as $EE(G)=\\sum_{i=1}^{n}e^{\\lambda_i(G)}$. In this paper we determine the unique graph with maximum Estrada index among bicyclic graphs with fixed order.
Maximum privacy without coherence, zero-error
Leung, Debbie; Yu, Nengkun
2016-09-01
We study the possible difference between the quantum and the private capacities of a quantum channel in the zero-error setting. For a family of channels introduced by Leung et al. [Phys. Rev. Lett. 113, 030512 (2014)], we demonstrate an extreme difference: the zero-error quantum capacity is zero, whereas the zero-error private capacity is maximum given the quantum output dimension.
Automatic maximum entropy spectral reconstruction in NMR.
Mobli, Mehdi; Maciejewski, Mark W; Gryk, Michael R; Hoch, Jeffrey C
2007-10-01
Developments in superconducting magnets, cryogenic probes, isotope labeling strategies, and sophisticated pulse sequences together have enabled the application, in principle, of high-resolution NMR spectroscopy to biomolecular systems approaching 1 megadalton. In practice, however, conventional approaches to NMR that utilize the fast Fourier transform, which require data collected at uniform time intervals, result in prohibitively lengthy data collection times in order to achieve the full resolution afforded by high field magnets. A variety of approaches that involve nonuniform sampling have been proposed, each utilizing a non-Fourier method of spectrum analysis. A very general non-Fourier method that is capable of utilizing data collected using any of the proposed nonuniform sampling strategies is maximum entropy reconstruction. A limiting factor in the adoption of maximum entropy reconstruction in NMR has been the need to specify non-intuitive parameters. Here we describe a fully automated system for maximum entropy reconstruction that requires no user-specified parameters. A web-accessible script generator provides the user interface to the system.
Maximum entropy analysis of cosmic ray composition
Nosek, Dalibor; Vícha, Jakub; Trávníček, Petr; Nosková, Jana
2016-01-01
We focus on the primary composition of cosmic rays with the highest energies that cause extensive air showers in the Earth's atmosphere. A way of examining the two lowest order moments of the sample distribution of the depth of shower maximum is presented. The aim is to show that useful information about the composition of the primary beam can be inferred with limited knowledge we have about processes underlying these observations. In order to describe how the moments of the depth of shower maximum depend on the type of primary particles and their energies, we utilize a superposition model. Using the principle of maximum entropy, we are able to determine what trends in the primary composition are consistent with the input data, while relying on a limited amount of information from shower physics. Some capabilities and limitations of the proposed method are discussed. In order to achieve a realistic description of the primary mass composition, we pay special attention to the choice of the parameters of the sup...
A Maximum Resonant Set of Polyomino Graphs
Zhang Heping
2016-05-01
Full Text Available A polyomino graph P is a connected finite subgraph of the infinite plane grid such that each finite face is surrounded by a regular square of side length one and each edge belongs to at least one square. A dimer covering of P corresponds to a perfect matching. Different dimer coverings can interact via an alternating cycle (or square with respect to them. A set of disjoint squares of P is a resonant set if P has a perfect matching M so that each one of those squares is M-alternating. In this paper, we show that if K is a maximum resonant set of P, then P − K has a unique perfect matching. We further prove that the maximum forcing number of a polyomino graph is equal to the cardinality of a maximum resonant set. This confirms a conjecture of Xu et al. [26]. We also show that if K is a maximal alternating set of P, then P − K has a unique perfect matching.
The maximum rate of mammal evolution
Evans, Alistair R.; Jones, David; Boyer, Alison G.; Brown, James H.; Costa, Daniel P.; Ernest, S. K. Morgan; Fitzgerald, Erich M. G.; Fortelius, Mikael; Gittleman, John L.; Hamilton, Marcus J.; Harding, Larisa E.; Lintulaakso, Kari; Lyons, S. Kathleen; Okie, Jordan G.; Saarinen, Juha J.; Sibly, Richard M.; Smith, Felisa A.; Stephens, Patrick R.; Theodor, Jessica M.; Uhen, Mark D.
2012-03-01
How fast can a mammal evolve from the size of a mouse to the size of an elephant? Achieving such a large transformation calls for major biological reorganization. Thus, the speed at which this occurs has important implications for extensive faunal changes, including adaptive radiations and recovery from mass extinctions. To quantify the pace of large-scale evolution we developed a metric, clade maximum rate, which represents the maximum evolutionary rate of a trait within a clade. We applied this metric to body mass evolution in mammals over the last 70 million years, during which multiple large evolutionary transitions occurred in oceans and on continents and islands. Our computations suggest that it took a minimum of 1.6, 5.1, and 10 million generations for terrestrial mammal mass to increase 100-, and 1,000-, and 5,000-fold, respectively. Values for whales were down to half the length (i.e., 1.1, 3, and 5 million generations), perhaps due to the reduced mechanical constraints of living in an aquatic environment. When differences in generation time are considered, we find an exponential increase in maximum mammal body mass during the 35 million years following the Cretaceous-Paleogene (K-Pg) extinction event. Our results also indicate a basic asymmetry in macroevolution: very large decreases (such as extreme insular dwarfism) can happen at more than 10 times the rate of increases. Our findings allow more rigorous comparisons of microevolutionary and macroevolutionary patterns and processes.
Minimal Length, Friedmann Equations and Maximum Density
Awad, Adel
2014-01-01
Inspired by Jacobson's thermodynamic approach[gr-qc/9504004], Cai et al [hep-th/0501055,hep-th/0609128] have shown the emergence of Friedmann equations from the first law of thermodynamics. We extend Akbar--Cai derivation [hep-th/0609128] of Friedmann equations to accommodate a general entropy-area law. Studying the resulted Friedmann equations using a specific entropy-area law, which is motivated by the generalized uncertainty principle (GUP), reveals the existence of a maximum energy density closed to Planck density. Allowing for a general continuous pressure $p(\\rho,a)$ leads to bounded curvature invariants and a general nonsingular evolution. In this case, the maximum energy density is reached in a finite time and there is no cosmological evolution beyond this point which leaves the big bang singularity inaccessible from a spacetime prospective. The existence of maximum energy density and a general nonsingular evolution is independent of the equation of state and the spacial curvature $k$. As an example w...
Maximum saliency bias in binocular fusion
Lu, Yuhao; Stafford, Tom; Fox, Charles
2016-07-01
Subjective experience at any instant consists of a single ("unitary"), coherent interpretation of sense data rather than a "Bayesian blur" of alternatives. However, computation of Bayes-optimal actions has no role for unitary perception, instead being required to integrate over every possible action-percept pair to maximise expected utility. So what is the role of unitary coherent percepts, and how are they computed? Recent work provided objective evidence for non-Bayes-optimal, unitary coherent, perception and action in humans; and further suggested that the percept selected is not the maximum a posteriori percept but is instead affected by utility. The present study uses a binocular fusion task first to reproduce the same effect in a new domain, and second, to test multiple hypotheses about exactly how utility may affect the percept. After accounting for high experimental noise, it finds that both Bayes optimality (maximise expected utility) and the previously proposed maximum-utility hypothesis are outperformed in fitting the data by a modified maximum-salience hypothesis, using unsigned utility magnitudes in place of signed utilities in the bias function.
The maximum rate of mammal evolution
Evans, Alistair R.; Jones, David; Boyer, Alison G.; Brown, James H.; Costa, Daniel P.; Ernest, S. K. Morgan; Fitzgerald, Erich M. G.; Fortelius, Mikael; Gittleman, John L.; Hamilton, Marcus J.; Harding, Larisa E.; Lintulaakso, Kari; Lyons, S. Kathleen; Okie, Jordan G.; Saarinen, Juha J.; Sibly, Richard M.; Smith, Felisa A.; Stephens, Patrick R.; Theodor, Jessica M.; Uhen, Mark D.
2012-01-01
How fast can a mammal evolve from the size of a mouse to the size of an elephant? Achieving such a large transformation calls for major biological reorganization. Thus, the speed at which this occurs has important implications for extensive faunal changes, including adaptive radiations and recovery from mass extinctions. To quantify the pace of large-scale evolution we developed a metric, clade maximum rate, which represents the maximum evolutionary rate of a trait within a clade. We applied this metric to body mass evolution in mammals over the last 70 million years, during which multiple large evolutionary transitions occurred in oceans and on continents and islands. Our computations suggest that it took a minimum of 1.6, 5.1, and 10 million generations for terrestrial mammal mass to increase 100-, and 1,000-, and 5,000-fold, respectively. Values for whales were down to half the length (i.e., 1.1, 3, and 5 million generations), perhaps due to the reduced mechanical constraints of living in an aquatic environment. When differences in generation time are considered, we find an exponential increase in maximum mammal body mass during the 35 million years following the Cretaceous–Paleogene (K–Pg) extinction event. Our results also indicate a basic asymmetry in macroevolution: very large decreases (such as extreme insular dwarfism) can happen at more than 10 times the rate of increases. Our findings allow more rigorous comparisons of microevolutionary and macroevolutionary patterns and processes. PMID:22308461
Maximum-biomass prediction of homofermentative Lactobacillus.
Cui, Shumao; Zhao, Jianxin; Liu, Xiaoming; Chen, Yong Q; Zhang, Hao; Chen, Wei
2016-07-01
Fed-batch and pH-controlled cultures have been widely used for industrial production of probiotics. The aim of this study was to systematically investigate the relationship between the maximum biomass of different homofermentative Lactobacillus and lactate accumulation, and to develop a prediction equation for the maximum biomass concentration in such cultures. The accumulation of the end products and the depletion of nutrients by various strains were evaluated. In addition, the minimum inhibitory concentrations (MICs) of acid anions for various strains at pH 7.0 were examined. The lactate concentration at the point of complete inhibition was not significantly different from the MIC of lactate for all of the strains, although the inhibition mechanism of lactate and acetate on Lactobacillus rhamnosus was different from the other strains which were inhibited by the osmotic pressure caused by acid anions at pH 7.0. When the lactate concentration accumulated to the MIC, the strains stopped growing. The maximum biomass was closely related to the biomass yield per unit of lactate produced (YX/P) and the MIC (C) of lactate for different homofermentative Lactobacillus. Based on the experimental data obtained using different homofermentative Lactobacillus, a prediction equation was established as follows: Xmax - X0 = (0.59 ± 0.02)·YX/P·C.
The maximum rate of mammal evolution.
Evans, Alistair R; Jones, David; Boyer, Alison G; Brown, James H; Costa, Daniel P; Ernest, S K Morgan; Fitzgerald, Erich M G; Fortelius, Mikael; Gittleman, John L; Hamilton, Marcus J; Harding, Larisa E; Lintulaakso, Kari; Lyons, S Kathleen; Okie, Jordan G; Saarinen, Juha J; Sibly, Richard M; Smith, Felisa A; Stephens, Patrick R; Theodor, Jessica M; Uhen, Mark D
2012-03-13
How fast can a mammal evolve from the size of a mouse to the size of an elephant? Achieving such a large transformation calls for major biological reorganization. Thus, the speed at which this occurs has important implications for extensive faunal changes, including adaptive radiations and recovery from mass extinctions. To quantify the pace of large-scale evolution we developed a metric, clade maximum rate, which represents the maximum evolutionary rate of a trait within a clade. We applied this metric to body mass evolution in mammals over the last 70 million years, during which multiple large evolutionary transitions occurred in oceans and on continents and islands. Our computations suggest that it took a minimum of 1.6, 5.1, and 10 million generations for terrestrial mammal mass to increase 100-, and 1,000-, and 5,000-fold, respectively. Values for whales were down to half the length (i.e., 1.1, 3, and 5 million generations), perhaps due to the reduced mechanical constraints of living in an aquatic environment. When differences in generation time are considered, we find an exponential increase in maximum mammal body mass during the 35 million years following the Cretaceous-Paleogene (K-Pg) extinction event. Our results also indicate a basic asymmetry in macroevolution: very large decreases (such as extreme insular dwarfism) can happen at more than 10 times the rate of increases. Our findings allow more rigorous comparisons of microevolutionary and macroevolutionary patterns and processes.
Campbell, Calista; Lubner, Meghan G; Hinshaw, J Louis; Muñoz del Rio, Alejandro; Brace, Christopher L
2012-09-01
The purpose of this study is to determine a concentration of iodinated contrast media in saline and 5% dextrose in water (D5W) for organ hydrodissection, a technique used to physically separate and protect tissues adjacent to thermal ablations. A total of 28 samples were prepared from 1:1000-1:1 iohexol or iothalamate meglumine contrast media in either normal saline or D5W. Samples alone or juxtaposed with a homogeneous liver-mimicking phantom were imaged by CT using 80-120 kVp and 10-300 mAs. Mean CT numbers and noise were measured from the fluid, background air, phantom adjacent to the fluid, and phantom distant from the fluid. Visibility was determined from the contrast-to-noise ratio between the fluid and phantom, whereas streaking artifact was quantified by relative noise in the phantom. Measures were individually fit using multiple linear regression to determine an optimal contrast-to-fluid ratio for increased visualization without streaking. Contrast media- and blood-doped saline and D5W were also tested to determine whether such doping altered their electrical conductivity. Iohexol concentration most influenced CT number; volumetric ratios of 1:1000-1:1 produced 20 HU to over 3000 HU. CT numbers were weakly dependent on x-ray tube voltage, whereas contrast-to-noise ratio and streaking artifacts were somewhat dependent on tube output. An optimal ratio of iohexol in fluid was determined to be 1:50. There was no significant difference between the electrical impedances of doped and pure saline or D5W (p > 0.5, all cases). A 1:50 ratio of iohexol in saline or D5W provides an optimal combination of increased visibility on CT without streaking artifacts.
Measurement and relevance of maximum metabolic rate in fishes.
Norin, T; Clark, T D
2016-01-01
Maximum (aerobic) metabolic rate (MMR) is defined here as the maximum rate of oxygen consumption (M˙O2max ) that a fish can achieve at a given temperature under any ecologically relevant circumstance. Different techniques exist for eliciting MMR of fishes, of which swim-flume respirometry (critical swimming speed tests and burst-swimming protocols) and exhaustive chases are the most common. Available data suggest that the most suitable method for eliciting MMR varies with species and ecotype, and depends on the propensity of the fish to sustain swimming for extended durations as well as its capacity to simultaneously exercise and digest food. MMR varies substantially (>10 fold) between species with different lifestyles (i.e. interspecific variation), and to a lesser extent (aerobic scope, interest in measuring this trait has spread across disciplines in attempts to predict effects of climate change on fish populations. Here, various techniques used to elicit and measure MMR in different fish species with contrasting lifestyles are outlined and the relevance of MMR to the ecology, fitness and climate change resilience of fishes is discussed.
Observation of Enhanced Transformer Ratio in Collinear Wakefield Acceleration
Jing, C.; Kanareykin, A.; Power, J. G.; Conde, M.; Yusof, Z.; Schoessow, P.; Gai, W.
2007-04-01
One approach to future high energy particle accelerators is based on the wakefield principle: a leading high-charge drive bunch is used to excite fields in an accelerating structure or plasma that in turn accelerates a trailing low-charge witness bunch. The transformer ratio R is defined as the ratio of the maximum energy gain of the witness bunch to the maximum energy loss of the drive bunch. In general, Rtransformer ratio limitation. We report here the first experimental study of the ramped bunch train (RBT) technique in a dielectric based accelerating structure. A single drive bunch was replaced by two bunches with charge ratio of 1∶2.5 and a separation of 10.5 wavelengths of the fundamental mode. An average measured transformer ratio enhancement by a factor of 1.31 over the single drive bunch case was obtained.
Critical Concentration Ratio for Solar Thermoelectric Generators
ur Rehman, Naveed; Siddiqui, Mubashir Ali
2016-10-01
A correlation for determining the critical concentration ratio (CCR) of solar concentrated thermoelectric generators (SCTEGs) has been established, and the significance of the contributing parameters is discussed in detail. For any SCTEG, higher concentration ratio leads to higher temperatures at the hot side of modules. However, the maximum value of this temperature for safe operation is limited by the material properties of the modules and should be considered as an important design constraint. Taking into account this limitation, the CCR can be defined as the maximum concentration ratio usable for a particular SCTEG. The established correlation is based on factors associated with the material and geometric properties of modules, thermal characteristics of the receiver, installation site attributes, and thermal and electrical operating conditions. To reduce the number of terms in the correlation, these factors are combined to form dimensionless groups by applying the Buckingham Pi theorem. A correlation model containing these groups is proposed and fit to a dataset obtained by simulating a thermodynamic (physical) model over sampled values acquired by applying the Latin hypercube sampling (LHS) technique over a realistic distribution of factors. The coefficient of determination and relative error are found to be 97% and ±20%, respectively. The correlation is validated by comparing the predicted results with literature values. In addition, the significance and effects of the Pi groups on the CCR are evaluated and thoroughly discussed. This study will lead to a wide range of opportunities regarding design and optimization of SCTEGs.
Gutzeit, Andreas; Roos, Justus E; Hergan, Klaus; von Weymarn, Constantin; Wälti, Stephan; Reischauer, Carolin; Froehlich, Johannes M
2014-12-01
Optimal contrast within the pulmonary artery is achieved by the maximum amount of contrast-enhanced blood flowing through the superior vena cava (SVC), while minimum amounts of non-contrasted blood should originate from the inferior vena cava (IVC). This study aims to clarify whether "suction against resistance" might optimise this ratio. Phase-contrast pulse sequences on a 1.5T MRI magnet were used for flow quantification (mean flow (mL/s), stroke volume (Vol) in the SVC and IVC in volunteers. Different breathing manoeuvers were analysed repeatedly: free breathing; inspiration; expiration; suction against resistance, and Valsalva. To standardise breathing commands, volunteers performed suction and Valsalva manoeuvers with an MR-compatible manometer. Suction against resistance was associated with a significant drop of the IVC/SVC flow quotient (1.63 [range 1.3-2.0] p 0.05). Suction against resistance caused a significant drop in the IVC/SVC quotient. Theoretically, this breathing manoeuver might significantly improve the enhancement characteristics of CT angiography. Suction provokes reduction in blood flow in the inferior vena cava. Ratio between the inferior and superior vena cava blood flow diminished during suction. Manometer used during breathing standardises MR phase-contrast blood flow measurements.
Contrast Enhancement through Clustered Histogram Equalization
Shen-Chuan Tai
2012-09-01
Full Text Available This study proposed a contrast enhancement algorithm. Some methods enhance images depending on only the global or the local information, therefore it would cause over-enhancement usually and make the image look unnatural. The proposed method enhances image based on the global and local information. For the global part, we proposed mapping curves to find the new average, maximum and minimum intensity to try to suit the concept of Human Visual System (HVS for obtaining the better perceptual results. For the local part, we utilized fuzzy c-means clustering algorithm to group image and we can obtain the information of intensity distribution and pixel number from each group. Then we calculate weights according to the information and enhance images by Histogram Equalization (HE depending on the weights. The experiment results show that our method can enhance the contrast of image steadily and it causes over-enhancement with lower probability than other methods. The whole image not only looks natural but also shows detail texture more clearly after applying our method.
Intensity contrast of the average supergranule
Langfellner, J; Gizon, L
2016-01-01
While the velocity fluctuations of supergranulation dominate the spectrum of solar convection at the solar surface, very little is known about the fluctuations in other physical quantities like temperature or density at supergranulation scale. Using SDO/HMI observations, we characterize the intensity contrast of solar supergranulation at the solar surface. We identify the positions of ${\\sim}10^4$ outflow and inflow regions at supergranulation scales, from which we construct average flow maps and co-aligned intensity and magnetic field maps. In the average outflow center, the maximum intensity contrast is $(7.8\\pm0.6)\\times10^{-4}$ (there is no corresponding feature in the line-of-sight magnetic field). This corresponds to a temperature perturbation of about $1.1\\pm0.1$ K, in agreement with previous studies. We discover an east-west anisotropy, with a slightly deeper intensity minimum east of the outflow center. The evolution is asymmetric in time: the intensity excess is larger 8 hours before the reference t...
Lefever, A. E.
1982-01-01
Proposed arrangement of two connected planetary differentials results in gear ratio many times that obtainable in conventional series gear assembly of comparable size. Ratios of several thousand would present no special problems. Selection of many different ratios is available with substantially similar gear diameters. Very high gear ratios would be obtained from small mechanism.
Behaviour of Organic Carbon in Nine Contrasting European Estuaries
Abril, G.; Nogueira, M.; Etcheber, H.; Cabeçadas, G.; Lemaire, E.; Brogueira, M. J.
2002-02-01
A cross-system comparison of organic carbon origin and behaviour in nine European estuaries is presented. The study sites display a very large range of hydrological and environmental conditions. The watershed of the respective estuaries were characterized by plotting the total organic carbon (TOC) in the rivers versus the inhabitants/discharge ratio. This allows to distinguish four types of watershed with regard to anthropogenic forcing and organic carbon levels: polluted by sewage inputs (Scheldt and to a much lesser extent, Ems, Sado and Thames), decontaminated (Elbe and Rhine), pristine (Gironde and Douro) and eutrophized (Loire and Scheldt). In the estuarine zone, dissolved organic carbon (DOC) almost always decreased linearly with increasing salinity. Exceptions were: the Scheldt, where a net consumption of sewage-derived DOC was observed, the Gironde, where a net production of DOC occurred in the maximum turbidity zone (MTZ) and the Sado and Ems, where DOC was supplied from large intertidal areas. By contrast, a large fraction of the riverine particulate organic carbon (POC) was mineralized in all the estuaries, except the Douro, where residence time of waters is only a few days. A fraction of POC appeared however refractory and accumulated in the MTZs, where terrestrial soil-derived material dominates (Elbe, Ems, Loire, Gironde and Sado). In the marine regions of most estuaries, autochthonous POC was present during spring and summer. The analysis of all river and estuarine data allows estimation of the loss of continental POC occurring in each estuary. It decreases in the following order: Scheldt≫Thames>Ems=Sado=Loire>Gironde>Elbe>Rhine>Douro, which almost corresponds to the anthropogenic pressure in the respective watersheds. Two major variables appear to control the intensity of this mineralization: the origin of the POC, the lability increasing with pollution, and the residence time of particles in the estuarine zone.
Missios Anna
2009-01-01
Full Text Available Abstract Background Primary intracardiac tumours are rare, there are however several entities that can mimic tumours. Contrast echocardiography has been suggested to aid the differentiation of various suspected masses. We present a case where transthoracic echocardiography completely misdiagnosed a left atrial mass, partly due to use of echo contrast. Case presentation An 80 year-old woman was referred for transthoracic echocardiography because of one-month duration of worsening of dyspnoea. Transthoracic echocardiography displayed a large echodense mass in the left atrium. Intravenous injection of contrast (SonoVue, Bracco Inc., It indicated contrast-enhancement of the structure, suggesting tumour. Transesophageal echocardiography revealed, however, a completely normal finding in the left atrium. Subsequent gastroscopy examination showed a hiatal hernia. Conclusion It is noteworthy that the transthoracic echocardiographic exam completely misdiagnosed what seemed like a left atrial mass, which in part was an effect of the use of echo contrast. This example highlights that liberal use of transoesophageal echocardiography is often warranted if optimal display of cardiac structures is desired.
Xing, Xiaoying; Zeng, Xiangzhu; Li, Xuan; Zhao, Qiang; Kirchin, Miles A; Pirovano, Gianpaolo; Wang, Xiaoying; Li, Yuan; Iezzi, Roberto; De Cobelli, Francesco
2015-02-01
The authors prospectively compared single dose (0.1 mmol/kg bodyweight) gadobenate dimeglumine with double dose (0.2 mmol/kg bodyweight) gadopentetate dimeglumine for contrast-enhanced magnetic resonance angiography (CE-MRA) in patients with suspected or known steno-occlusive disease of the carotid, renal or peripheral vasculature using an intra-individual crossover study design. Twenty-eight patients with suspected or known steno-occlusive disease of the carotid (n = 16), renal (n = 5) or peripheral arteries (n = 7) were randomised to receive either 0.1 mmol/kg gadobenate dimeglumine or 0.2 mmol/kg gadopentetate dimeglumine for a first CE-MRA procedure. After 3-5 days all patients underwent a second identical CE-MRA procedure with the other contrast agent. Three blinded readers assessed images for vessel anatomical delineation, disease detection/exclusion, and global preference. Diagnostic performance for detection of ≥51 % stenosis was determined for 20/28 patients who also underwent digital subtraction angiography (DSA). Non-inferiority was assessed using the Wilcoxon signed rank, McNemar and Wald tests. Quantitative (signal-to-noise and contrast-to-noise ratio) enhancement based on 3D maximum intensity projection reconstructions was compared. No differences were noted for any qualitative parameter. Equivalence was reported for all diagnostic preference end-points. Superiority for gadobenate dimeglumine was reported by all readers for sensitivity for disease detection (80.8-86.5 vs. 75.0-82.7 %). Quantitative enhancement was similar for single dose gadobenate dimeglumine and double dose gadopentetate dimeglumine. Under identical examination conditions a single 0.1 mmol/kg body weight dose of gadobenate dimeglumine can fully replace a double 0.2 mmol/kg body weight dose of gadopentetate dimeglumine for routine CE-MRA procedures.
Multiscale image contrast amplification (MUSICA)
Vuylsteke, Pieter; Schoeters, Emile P.
1994-05-01
This article presents a novel approach to the problem of detail contrast enhancement, based on multiresolution representation of the original image. The image is decomposed into a weighted sum of smooth, localized, 2D basis functions at multiple scales. Each transform coefficient represents the amount of local detail at some specific scale and at a specific position in the image. Detail contrast is enhanced by non-linear amplification of the transform coefficients. An inverse transform is then applied to the modified coefficients. This yields a uniformly contrast- enhanced image without artefacts. The MUSICA-algorithm is being applied routinely to computed radiography images of chest, skull, spine, shoulder, pelvis, extremities, and abdomen examinations, with excellent acceptance. It is useful for a wide range of applications in the medical, graphical, and industrial area.
Subharmonic imaging of contrast agents.
Forsberg, F; Shi, W T; Goldberg, B B
2000-03-01
Ultrasound contrast agents promise to improve the sensitivity and specificity of diagnostic ultrasound imaging. It is of great importance to adapt ultrasound equipment for optimal use with contrast agents e.g., by exploiting the nonlinear properties of the contrast microbubbles. Harmonic imaging is one technique that has been extensively studied and is commercially available. However, harmonic imaging is associated with problems, due to second harmonic generation and accumulation within the tissue itself. Given the lack of subharmonic generation in tissue, one alternative is the creation of subharmonic images by transmitting at the fundamental frequency (fo) and receiving at the subharmonic (fo/2). Subharmonic imaging should have a much better lateral resolution and may be suitable for scanning deep-lying structures owing to the higher transmit frequency and the much smaller attenuation of scattered subharmonic signals. In this paper, we will review different aspects of subharmonic imaging including implementation, in-vitro gray-scale imaging and subharmonic aided pressure estimation.
Maximum power operation of interacting molecular motors
Golubeva, Natalia; Imparato, Alberto
2013-01-01
We study the mechanical and thermodynamic properties of different traffic models for kinesin which are relevant in biological and experimental contexts. We find that motor-motor interactions play a fundamental role by enhancing the thermodynamic efficiency at maximum power of the motors......, as compared to the non-interacting system, in a wide range of biologically compatible scenarios. We furthermore consider the case where the motor-motor interaction directly affects the internal chemical cycle and investigate the effect on the system dynamics and thermodynamics....
Maximum a posteriori decoder for digital communications
Altes, Richard A. (Inventor)
1997-01-01
A system and method for decoding by identification of the most likely phase coded signal corresponding to received data. The present invention has particular application to communication with signals that experience spurious random phase perturbations. The generalized estimator-correlator uses a maximum a posteriori (MAP) estimator to generate phase estimates for correlation with incoming data samples and for correlation with mean phases indicative of unique hypothesized signals. The result is a MAP likelihood statistic for each hypothesized transmission, wherein the highest value statistic identifies the transmitted signal.
Kernel-based Maximum Entropy Clustering
JIANG Wei; QU Jiao; LI Benxi
2007-01-01
With the development of Support Vector Machine (SVM),the "kernel method" has been studied in a general way.In this paper,we present a novel Kernel-based Maximum Entropy Clustering algorithm (KMEC).By using mercer kernel functions,the proposed algorithm is firstly map the data from their original space to high dimensional space where the data are expected to be more separable,then perform MEC clustering in the feature space.The experimental results show that the proposed method has better performance in the non-hyperspherical and complex data structure.
The sun and heliosphere at solar maximum.
Smith, E J; Marsden, R G; Balogh, A; Gloeckler, G; Geiss, J; McComas, D J; McKibben, R B; MacDowall, R J; Lanzerotti, L J; Krupp, N; Krueger, H; Landgraf, M
2003-11-14
Recent Ulysses observations from the Sun's equator to the poles reveal fundamental properties of the three-dimensional heliosphere at the maximum in solar activity. The heliospheric magnetic field originates from a magnetic dipole oriented nearly perpendicular to, instead of nearly parallel to, the Sun's rotation axis. Magnetic fields, solar wind, and energetic charged particles from low-latitude sources reach all latitudes, including the polar caps. The very fast high-latitude wind and polar coronal holes disappear and reappear together. Solar wind speed continues to be inversely correlated with coronal temperature. The cosmic ray flux is reduced symmetrically at all latitudes.
Conductivity maximum in a charged colloidal suspension
Bastea, S
2009-01-27
Molecular dynamics simulations of a charged colloidal suspension in the salt-free regime show that the system exhibits an electrical conductivity maximum as a function of colloid charge. We attribute this behavior to two main competing effects: colloid effective charge saturation due to counterion 'condensation' and diffusion slowdown due to the relaxation effect. In agreement with previous observations, we also find that the effective transported charge is larger than the one determined by the Stern layer and suggest that it corresponds to the boundary fluid layer at the surface of the colloidal particles.
Maximum entropy signal restoration with linear programming
Mastin, G.A.; Hanson, R.J.
1988-05-01
Dantzig's bounded-variable method is used to express the maximum entropy restoration problem as a linear programming problem. This is done by approximating the nonlinear objective function with piecewise linear segments, then bounding the variables as a function of the number of segments used. The use of a linear programming approach allows equality constraints found in the traditional Lagrange multiplier method to be relaxed. A robust revised simplex algorithm is used to implement the restoration. Experimental results from 128- and 512-point signal restorations are presented.
COMPARISON BETWEEN FORMULAS OF MAXIMUM SHIP SQUAT
PETRU SERGIU SERBAN
2016-06-01
Full Text Available Ship squat is a combined effect of ship’s draft and trim increase due to ship motion in limited navigation conditions. Over time, researchers conducted tests on models and ships to find a mathematical formula that can define squat. Various forms of calculating squat can be found in the literature. Among those most commonly used are of Barrass, Millward, Eryuzlu or ICORELS. This paper presents a comparison between the squat formulas to see the differences between them and which one provides the most satisfactory results. In this respect a cargo ship at different speeds was considered as a model for maximum squat calculations in canal navigation conditions.
Maximum entropy PDF projection: A review
Baggenstoss, Paul M.
2017-06-01
We review maximum entropy (MaxEnt) PDF projection, a method with wide potential applications in statistical inference. The method constructs a sampling distribution for a high-dimensional vector x based on knowing the sampling distribution p(z) of a lower-dimensional feature z = T (x). Under mild conditions, the distribution p(x) having highest possible entropy among all distributions consistent with p(z) may be readily found. Furthermore, the MaxEnt p(x) may be sampled, making the approach useful in Monte Carlo methods. We review the theorem and present a case study in model order selection and classification for handwritten character recognition.
CORA: Emission Line Fitting with Maximum Likelihood
Ness, Jan-Uwe; Wichmann, Rainer
2011-12-01
CORA analyzes emission line spectra with low count numbers and fits them to a line using the maximum likelihood technique. CORA uses a rigorous application of Poisson statistics. From the assumption of Poissonian noise, the software derives the probability for a model of the emission line spectrum to represent the measured spectrum. The likelihood function is used as a criterion for optimizing the parameters of the theoretical spectrum and a fixed point equation is derived allowing an efficient way to obtain line fluxes. CORA has been applied to an X-ray spectrum with the Low Energy Transmission Grating Spectrometer (LETGS) on board the Chandra observatory.
Dynamical maximum entropy approach to flocking
Cavagna, Andrea; Giardina, Irene; Ginelli, Francesco; Mora, Thierry; Piovani, Duccio; Tavarone, Raffaele; Walczak, Aleksandra M.
2014-04-01
We derive a new method to infer from data the out-of-equilibrium alignment dynamics of collectively moving animal groups, by considering the maximum entropy model distribution consistent with temporal and spatial correlations of flight direction. When bird neighborhoods evolve rapidly, this dynamical inference correctly learns the parameters of the model, while a static one relying only on the spatial correlations fails. When neighbors change slowly and the detailed balance is satisfied, we recover the static procedure. We demonstrate the validity of the method on simulated data. The approach is applicable to other systems of active matter.
Maximum Temperature Detection System for Integrated Circuits
Frankiewicz, Maciej; Kos, Andrzej
2015-03-01
The paper describes structure and measurement results of the system detecting present maximum temperature on the surface of an integrated circuit. The system consists of the set of proportional to absolute temperature sensors, temperature processing path and a digital part designed in VHDL. Analogue parts of the circuit where designed with full-custom technique. The system is a part of temperature-controlled oscillator circuit - a power management system based on dynamic frequency scaling method. The oscillator cooperates with microprocessor dedicated for thermal experiments. The whole system is implemented in UMC CMOS 0.18 μm (1.8 V) technology.
Zipf's law and maximum sustainable growth
Malevergne, Y; Sornette, D
2010-01-01
Zipf's law states that the number of firms with size greater than S is inversely proportional to S. Most explanations start with Gibrat's rule of proportional growth but require additional constraints. We show that Gibrat's rule, at all firm levels, yields Zipf's law under a balance condition between the effective growth rate of incumbent firms (which includes their possible demise) and the growth rate of investments in entrant firms. Remarkably, Zipf's law is the signature of the long-term optimal allocation of resources that ensures the maximum sustainable growth rate of an economy.
The relative worst order ratio applied to paging
Boyar, Joan; Favrholdt, Lene Monrad; Larsen, Kim Skak
2007-01-01
The relative worst order ratio, a new measure for the quality of on-line algorithms, was recently defined and applied to two bin packing problems. Here, we apply it to the paging problem and obtain the following results: We devise a new deterministic paging algorithm, Retrospective-LRU, and show...... that it performs better than LRU. This is supported by experimental results, but contrasts with the competitive ratio. All deterministic marking algorithms have the same competitive ratio, but here we find that LRU is better than FWF. According to the relative worst order ratio, no deterministic marking algorithm...... can be significantly better than LRU, but the randomized algorithm MARK is better than LRU. Finally, look-ahead is shown to be a significant advantage, in contrast to the competitive ratio, which does not reflect that look-ahead can be helpful....
Optimal specific wavelength for maximum thrust production in undulatory propulsion.
Nangia, Nishant; Bale, Rahul; Chen, Nelson; Hanna, Yohanna; Patankar, Neelesh A
2017-01-01
What wavelengths do undulatory swimmers use during propulsion? In this work we find that a wide range of body/caudal fin (BCF) swimmers, from larval zebrafish and herring to fully-grown eels, use specific wavelength (ratio of wavelength to tail amplitude of undulation) values that fall within a relatively narrow range. The possible emergence of this constraint is interrogated using numerical simulations of fluid-structure interaction. Based on these, it was found that there is an optimal specific wavelength (OSW) that maximizes the swimming speed and thrust generated by an undulatory swimmer. The observed values of specific wavelength for BCF animals are relatively close to this OSW. The mechanisms underlying the maximum propulsive thrust for BCF swimmers are quantified and are found to be consistent with the mechanisms hypothesized in prior work. The adherence to an optimal value of specific wavelength in most natural hydrodynamic propulsors gives rise to empirical design criteria for man-made propulsors.
Contrast-induced acute kidney injury: how much contrast is safe?
Keaney, John J
2013-02-14
Iodinated contrast media (CM) are used in many investigations that a patient may undergo during the course of an in-patient stay. For the vast majority of patients, exposure to CM has no sequelae; however, in a small percentage, it can result in a worsening in renal function termed contrast-induced acute kidney injury (CI-AKI). CI-AKI is one of the leading causes of in-hospital renal dysfunction. It is associated with a significant increase in morbidity and mortality as well as an increased length of hospital stay and costs. Unfortunately, the results of extensive research into pharmacological inventions to prevent CI-AKI remain disappointing. In this article, we briefly outline the pathophysiological mechanisms by which iodinated CM may cause CI-AKI and discuss the evidence for reducing CI-AKI by limiting contrast volumes. In particular, we review the data surrounding the use of contrast volume to glomerular filtration rate ratios, which can be used by clinicians to effectively lower the incidence of CI-AKI in their patients.
A Method to Compensate for Display System Contrast Ratio Differences in Distributed Simulation
2009-07-01
video . Atmospheric effects can also be done this way, when used in conjunction with a rendered image representing depth (or slant range). In a...Step 2 is accomplished with the IDirect3DDevice::StretchRect method. This method moves the image rendered as an anti- aliased frame buffer to a video ...r0, c1.x ; r1 = r+g+b max r1, r1, c2.x ; clamp to a minimum value rcp r1.y, r1.x ; 1/TCU mul r0.rgb, r0, r1.y ; r,g
Accurate structural correlations from maximum likelihood superpositions.
Douglas L Theobald
2008-02-01
Full Text Available The cores of globular proteins are densely packed, resulting in complicated networks of structural interactions. These interactions in turn give rise to dynamic structural correlations over a wide range of time scales. Accurate analysis of these complex correlations is crucial for understanding biomolecular mechanisms and for relating structure to function. Here we report a highly accurate technique for inferring the major modes of structural correlation in macromolecules using likelihood-based statistical analysis of sets of structures. This method is generally applicable to any ensemble of related molecules, including families of nuclear magnetic resonance (NMR models, different crystal forms of a protein, and structural alignments of homologous proteins, as well as molecular dynamics trajectories. Dominant modes of structural correlation are determined using principal components analysis (PCA of the maximum likelihood estimate of the correlation matrix. The correlations we identify are inherently independent of the statistical uncertainty and dynamic heterogeneity associated with the structural coordinates. We additionally present an easily interpretable method ("PCA plots" for displaying these positional correlations by color-coding them onto a macromolecular structure. Maximum likelihood PCA of structural superpositions, and the structural PCA plots that illustrate the results, will facilitate the accurate determination of dynamic structural correlations analyzed in diverse fields of structural biology.
Maximum entropy production and the fluctuation theorem
Dewar, R C [Unite EPHYSE, INRA Centre de Bordeaux-Aquitaine, BP 81, 33883 Villenave d' Ornon Cedex (France)
2005-05-27
Recently the author used an information theoretical formulation of non-equilibrium statistical mechanics (MaxEnt) to derive the fluctuation theorem (FT) concerning the probability of second law violating phase-space paths. A less rigorous argument leading to the variational principle of maximum entropy production (MEP) was also given. Here a more rigorous and general mathematical derivation of MEP from MaxEnt is presented, and the relationship between MEP and the FT is thereby clarified. Specifically, it is shown that the FT allows a general orthogonality property of maximum information entropy to be extended to entropy production itself, from which MEP then follows. The new derivation highlights MEP and the FT as generic properties of MaxEnt probability distributions involving anti-symmetric constraints, independently of any physical interpretation. Physically, MEP applies to the entropy production of those macroscopic fluxes that are free to vary under the imposed constraints, and corresponds to selection of the most probable macroscopic flux configuration. In special cases MaxEnt also leads to various upper bound transport principles. The relationship between MaxEnt and previous theories of irreversible processes due to Onsager, Prigogine and Ziegler is also clarified in the light of these results. (letter to the editor)
Thermodynamic hardness and the maximum hardness principle
Franco-Pérez, Marco; Gázquez, José L.; Ayers, Paul W.; Vela, Alberto
2017-08-01
An alternative definition of hardness (called the thermodynamic hardness) within the grand canonical ensemble formalism is proposed in terms of the partial derivative of the electronic chemical potential with respect to the thermodynamic chemical potential of the reservoir, keeping the temperature and the external potential constant. This temperature dependent definition may be interpreted as a measure of the propensity of a system to go through a charge transfer process when it interacts with other species, and thus it keeps the philosophy of the original definition. When the derivative is expressed in terms of the three-state ensemble model, in the regime of low temperatures and up to temperatures of chemical interest, one finds that for zero fractional charge, the thermodynamic hardness is proportional to T-1(I -A ) , where I is the first ionization potential, A is the electron affinity, and T is the temperature. However, the thermodynamic hardness is nearly zero when the fractional charge is different from zero. Thus, through the present definition, one avoids the presence of the Dirac delta function. We show that the chemical hardness defined in this way provides meaningful and discernible information about the hardness properties of a chemical species exhibiting integer or a fractional average number of electrons, and this analysis allowed us to establish a link between the maximum possible value of the hardness here defined, with the minimum softness principle, showing that both principles are related to minimum fractional charge and maximum stability conditions.
Particle Ratios in Heavy-Ion Collisions
Tawfik, A
2005-01-01
In the framework of the statistical models, we calculated different particle ratios in the energy range \\hbox{$3.5$} ratios. We find within the statistical acceptance that the different peaks are located at one value of energy, $\\sqrt{s_{NN}}^{(c)}\\simeq7.5 $GeV. This energy value is corresponding to baryo-chemical potential of $\\mu_B\\simeq0.43 $GeV. We also found that a maximum entropy per particle is allocated at the same collision energy. The saddle-point in the entropy per particle likely refers to the critical endpoint which connects the first-order phase transition with the cross-over.
A maximum entropy model for opinions in social groups
Davis, Sergio; Navarrete, Yasmín; Gutiérrez, Gonzalo
2014-04-01
We study how the opinions of a group of individuals determine their spatial distribution and connectivity, through an agent-based model. The interaction between agents is described by a Hamiltonian in which agents are allowed to move freely without an underlying lattice (the average network topology connecting them is determined from the parameters). This kind of model was derived using maximum entropy statistical inference under fixed expectation values of certain probabilities that (we propose) are relevant to social organization. Control parameters emerge as Lagrange multipliers of the maximum entropy problem, and they can be associated with the level of consequence between the personal beliefs and external opinions, and the tendency to socialize with peers of similar or opposing views. These parameters define a phase diagram for the social system, which we studied using Monte Carlo Metropolis simulations. Our model presents both first and second-order phase transitions, depending on the ratio between the internal consequence and the interaction with others. We have found a critical value for the level of internal consequence, below which the personal beliefs of the agents seem to be irrelevant.
Noise and physical limits to maximum resolution of PET images
Herraiz, J.L.; Espana, S. [Dpto. Fisica Atomica, Molecular y Nuclear, Facultad de Ciencias Fisicas, Universidad Complutense de Madrid, Avda. Complutense s/n, E-28040 Madrid (Spain); Vicente, E.; Vaquero, J.J.; Desco, M. [Unidad de Medicina y Cirugia Experimental, Hospital GU ' Gregorio Maranon' , E-28007 Madrid (Spain); Udias, J.M. [Dpto. Fisica Atomica, Molecular y Nuclear, Facultad de Ciencias Fisicas, Universidad Complutense de Madrid, Avda. Complutense s/n, E-28040 Madrid (Spain)], E-mail: jose@nuc2.fis.ucm.es
2007-10-01
In this work we show that there is a limit for the maximum resolution achievable with a high resolution PET scanner, as well as for the best signal-to-noise ratio, which are ultimately related to the physical effects involved in the emission and detection of the radiation and thus they cannot be overcome with any particular reconstruction method. These effects prevent the spatial high frequency components of the imaged structures to be recorded by the scanner. Therefore, the information encoded in these high frequencies cannot be recovered by any reconstruction technique. Within this framework, we have determined the maximum resolution achievable for a given acquisition as a function of data statistics and scanner parameters, like the size of the crystals or the inter-crystal scatter. In particular, the noise level in the data as a limitation factor to yield high-resolution images in tomographs with small crystal sizes is outlined. These results have implications regarding how to decide the optimal number of voxels of the reconstructed image or how to design better PET scanners.
Maximum Allowable Dynamic Load of Mobile Manipulators with Stability Consideration
Heidary H. R.
2015-09-01
Full Text Available High payload to mass ratio is one of the advantages of mobile robot manipulators. In this paper, a general formula for finding the maximum allowable dynamic load (MADL of wheeled mobile robot is presented. Mobile manipulators operating in field environments will be required to manipulate large loads, and to perform such tasks on uneven terrain, which may cause the system to reach dangerous tip-over instability. Therefore, the method is expanded for finding the MADL of mobile manipulators with stability consideration. Moment-Height Stability (MHS criterion is used as an index for the system stability. Full dynamic model of wheeled mobile base and mounted manipulator is considered with respect to the dynamic of non-holonomic constraint. Then, a method for determination of the maximum allowable loads is described, subject to actuator constraints and by imposing the stability limitation as a new constraint. The actuator torque constraint is applied by using a speed-torque characteristics curve of a typical DC motor. In order to verify the effectiveness of the presented algorithm, several simulation studies considering a two-link planar manipulator, mounted on a mobile base are presented and the results are discussed.
Maximum hydrogen production from genetically modified microalgae biomass
Vargas, Jose; Kava, Vanessa; Ordonez, Juan
A transient mathematical model for managing microalgae derived H2 production as a source of renewable energy is developed for a well stirred photobioreactor, PBR. The model allows for the determination of microalgae and H2 mass fractions produced by the PBR in time. A Michaelis-Menten expression is proposed for modeling the rate of H2 production, which introduces an expression to calculate the resulting effect on H2 production rate after genetically modifying the microalgae. The indirect biophotolysis process was used. Therefore, an opportunity was found to optimize the aerobic to anaerobic stages time ratio of the cycle for maximum H2 production rate, i.e., the process rhythm. A system thermodynamic optimization is conducted with the model equations to find accurately the optimal system operating rhythm for maximum H2 production rate, and how wild and genetically modified species compare to each other. The maxima found are sharp, showing up to a ~60% variation in hydrogen production rate within 2 days around the optimal rhythm, which highlights the importance of system operation in such condition. Therefore, the model is expected to be useful for design, control and optimization of H2 production. Brazilian National Council of Scientific and Technological Development, CNPq (project 482336/2012-9).
Maximum mass of a barotropic spherical star
Fujisawa, Atsuhito; Yoo, Chul-Moon; Nambu, Yasusada
2015-01-01
The ratio of total mass $M$ to surface radius $R$ of spherical perfect fluid ball has an upper bound, $M/R < B$. Buchdahl obtained $B = 4/9$ under the assumptions; non-increasing mass density in outward direction, and barotropic equation of states. Barraco and Hamity decreased the Buchdahl's bound to a lower value $B = 3/8$ $(< 4/9)$ by adding the dominant energy condition to Buchdahl's assumptions. In this paper, we further decrease the Barraco-Hamity's bound to $B \\simeq 0.3636403$ $(< 3/8)$ by adding the subluminal (slower-than-light) condition of sound speed. In our analysis, we solve numerically Tolman-Oppenheimer-Volkoff equations, and the mass-to-radius ratio is maximized by variation of mass, radius and pressure inside the fluid ball as functions of mass density.
Contrast-enhanced endoscopic ultrasonography
Reddy, Nischita K; Ioncică, Ana Maria; Săftoiu, Adrian;
2011-01-01
cancers and visualization of the portal venous system and esophageal varices. In addition, contrast agents can be used to differentiate pancreatic lesions. The use of color Doppler further increases the ability to diagnose and differentiate various pancreatic malignancies. The sensitivity of power Doppler...
Lake Basin Fetch and Maximum Length/Width
Minnesota Department of Natural Resources — Linear features representing the Fetch, Maximum Length and Maximum Width of a lake basin. Fetch, maximum length and average width are calcuated from the lake polygon...
Hepatocellular carcinoma: perfusion quantification with dynamic contrast-enhanced MRI
Taouli, B.; Johnson, R.S.; Hajdu, C.H.; Oei, M.T.H.; Merad, M.; Yee, H.; Rusinek, H.
2013-01-01
The objective of our study was to report our initial experience with dynamic contrast-enhanced MRI (DCE-MRI) for perfusion quantification of hepatocellular carcinoma (HCC) and surrounding liver.DCE-MRI of the liver was prospectively performed on 31 patients with HCC (male-female ratio, 26:5; mean ag
Fredenberg, Erik; Danielsson, Mats; Stayman, J. Webster; Siewerdsen, Jeffrey H.; Aslund, Magnus [Research and Development, Philips Women' s Healthcare, Smidesvaegen 5, SE-171 41 Solna, Sweden and Department of Physics, Royal Institute of Technology, AlbaNova, SE-106 91 Stockholm (Sweden); Department of Physics, Royal Institute of Technology, AlbaNova, SE-106 91 Stockholm (Sweden); Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205 (United States); Department of Biomedical Engineering and Department of Radiology, Johns Hopkins University, Baltimore, Maryland 21205 (United States); Research and Development, Philips Women' s Healthcare, Smidesvaegen 5, SE-171 41 Solna (Sweden)
2012-09-15
Purpose: To provide a cascaded-systems framework based on the noise-power spectrum (NPS), modulation transfer function (MTF), and noise-equivalent number of quanta (NEQ) for quantitative evaluation of differential phase-contrast imaging (Talbot interferometry) in relation to conventional absorption contrast under equal-dose, equal-geometry, and, to some extent, equal-photon-economy constraints. The focus is a geometry for photon-counting mammography. Methods: Phase-contrast imaging is a promising technology that may emerge as an alternative or adjunct to conventional absorption contrast. In particular, phase contrast may increase the signal-difference-to-noise ratio compared to absorption contrast because the difference in phase shift between soft-tissue structures is often substantially larger than the absorption difference. We have developed a comprehensive cascaded-systems framework to investigate Talbot interferometry, which is a technique for differential phase-contrast imaging. Analytical expressions for the MTF and NPS were derived to calculate the NEQ and a task-specific ideal-observer detectability index under assumptions of linearity and shift invariance. Talbot interferometry was compared to absorption contrast at equal dose, and using either a plane wave or a spherical wave in a conceivable mammography geometry. The impact of source size and spectrum bandwidth was included in the framework, and the trade-off with photon economy was investigated in some detail. Wave-propagation simulations were used to verify the analytical expressions and to generate example images. Results: Talbot interferometry inherently detects the differential of the phase, which led to a maximum in NEQ at high spatial frequencies, whereas the absorption-contrast NEQ decreased monotonically with frequency. Further, phase contrast detects differences in density rather than atomic number, and the optimal imaging energy was found to be a factor of 1.7 higher than for absorption
Conformance contrast testing between rates of pulmonary tuberculosis in Ecuadorian border areas
Claudia Ortiz-Rico
2015-11-01
Full Text Available Objective. To estimate rates of cases of respiratory symptomatic subjects and the incidence rate of pulmonary tuberculosis in two border areas of Ecuador, and contrast them with official figures. Materials and methods. Cross-sectional survey in the southeastern (SEBA, and the Andean southern Ecuadorian border areas (ASBA, which were conducted, respectively, in 1 598 and 2 419 persons aged over 15 years recruited over periods of three weeks. In identified respiratory symptomatic cases, a sputum sample was taken for smear testing. The results (odds ratios and their respective 95% confidence intervals, were compared with local and national official figures using maximum likelihood contrasts. Results. The rates of respiratory symptomatic subjects (7.7% and 5.9% in the SEBA, and ASBA, respectively and of pulmonary tuberculosis (cumulative incidence rates of 125 and 140 per 100 000 inhabitants, in the same order were significantly greater than the official figures (of 0.98 and 0.99% for respiratory symptomatic subjects in the SEBA and ASBA, respectively; and of 38.23 per 100 000 inhabitants for pulmonary tuberculosis in Ecuador as a whole (p<0.001. Conclusion. It is necessary to reinforce both active case finding for respiratory symptomatic subject cases, and epidemiological surveillance of pulmonary tuberculosis in Ecuadorian border regions.
Ultrasound contrast imaging: influence of scatterer motion in multi-pulse techniques.
Lin, Fanglue; Cachard, Christian; Mori, Riccardo; Varray, Francois; Guidi, Francesco; Basset, Olivier
2013-10-01
In ultrasound contrast imaging, many techniques based on multiple transmissions have been proposed to increase the contrast-to-tissue ratio (CTR). They are generally based on the response of static scatterers inside the imaged region. However, scatterer motion, for example in blood vessels, has an inevitable influence on multi-pulse techniques, which can either enhance or degrade the technique involved. This paper investigates the response of static nonlinear media insonated by multi-pulses with various phase shifts, and the influence of scatterer motion on multi-pulse techniques. Simulations and experimental results from a single bubble and clouds of bubbles show that the phase shift of the echoes backscattered from bubbles is dependent on the transmissions' phase shift, and that the bubble motion influences the efficiency of multi-pulse techniques: fundamental and second-harmonic amplitudes of the processed signal change periodically, exhibiting maximum or minimum values, according to scatterer motion. Furthermore, experimental results based on the second-harmonic inversion (SHI) technique reveal that bubble motion can be taken into account to regulate the pulse repetition frequency (PRF). With the optimal PRF, the CTR of SHI images can be improved by about 12 dB compared with second-harmonic images.
Dynamic contrast enhanced MRI for perfusion quantification
Andersen, Irene Klærke
2002-01-01
to be more robust. Successful brain perfusion quantication based on R1 weighted signals has not previously been reported, due to the poor signal to noise ratio of the images. Initial experiments reported in this thesis show that improved sequence may provide more accurate perfusion estimates in the brain...... with the tissue IRF. To obtain the IRF, the tissue curves and the input curves are deconvolved and perfusion is related to the peak of IRF. In this thesis, a new method for deconvolution of perfusion data is introduced. It is the Gaussian process for deconvolution, GPD. The method is compared to singular value......Magnetic resonance imaging, during bolus passage of a paramagnetic contrast agent, is used world-wide to obtain parameters that reflect the pathological state of tissue. Abnormal perfusion occurs in diseases such as stoke and tumour. Consequently, perfusion quantication could have signi cant...
Maximum entropy principle and texture formation
Arminjon, M; Arminjon, Mayeul; Imbault, Didier
2006-01-01
The macro-to-micro transition in a heterogeneous material is envisaged as the selection of a probability distribution by the Principle of Maximum Entropy (MAXENT). The material is made of constituents, e.g. given crystal orientations. Each constituent is itself made of a large number of elementary constituents. The relevant probability is the volume fraction of the elementary constituents that belong to a given constituent and undergo a given stimulus. Assuming only obvious constraints in MAXENT means describing a maximally disordered material. This is proved to have the same average stimulus in each constituent. By adding a constraint in MAXENT, a new model, potentially interesting e.g. for texture prediction, is obtained.
MLDS: Maximum Likelihood Difference Scaling in R
Kenneth Knoblauch
2008-01-01
Full Text Available The MLDS package in the R programming language can be used to estimate perceptual scales based on the results of psychophysical experiments using the method of difference scaling. In a difference scaling experiment, observers compare two supra-threshold differences (a,b and (c,d on each trial. The approach is based on a stochastic model of how the observer decides which perceptual difference (or interval (a,b or (c,d is greater, and the parameters of the model are estimated using a maximum likelihood criterion. We also propose a method to test the model by evaluating the self-consistency of the estimated scale. The package includes an example in which an observer judges the differences in correlation between scatterplots. The example may be readily adapted to estimate perceptual scales for arbitrary physical continua.
Maximum Profit Configurations of Commercial Engines
Yiran Chen
2011-06-01
Full Text Available An investigation of commercial engines with finite capacity low- and high-price economic subsystems and a generalized commodity transfer law [n ∝ Δ (P m] in commodity flow processes, in which effects of the price elasticities of supply and demand are introduced, is presented in this paper. Optimal cycle configurations of commercial engines for maximum profit are obtained by applying optimal control theory. In some special cases, the eventual state—market equilibrium—is solely determined by the initial conditions and the inherent characteristics of two subsystems; while the different ways of transfer affect the model in respects of the specific forms of the paths of prices and the instantaneous commodity flow, i.e., the optimal configuration.
Maximum Segment Sum, Monadically (distilled tutorial
Jeremy Gibbons
2011-09-01
Full Text Available The maximum segment sum problem is to compute, given a list of integers, the largest of the sums of the contiguous segments of that list. This problem specification maps directly onto a cubic-time algorithm; however, there is a very elegant linear-time solution too. The problem is a classic exercise in the mathematics of program construction, illustrating important principles such as calculational development, pointfree reasoning, algebraic structure, and datatype-genericity. Here, we take a sideways look at the datatype-generic version of the problem in terms of monadic functional programming, instead of the traditional relational approach; the presentation is tutorial in style, and leavened with exercises for the reader.
Maximum Information and Quantum Prediction Algorithms
McElwaine, J N
1997-01-01
This paper describes an algorithm for selecting a consistent set within the consistent histories approach to quantum mechanics and investigates its properties. The algorithm uses a maximum information principle to select from among the consistent sets formed by projections defined by the Schmidt decomposition. The algorithm unconditionally predicts the possible events in closed quantum systems and ascribes probabilities to these events. A simple spin model is described and a complete classification of all exactly consistent sets of histories formed from Schmidt projections in the model is proved. This result is used to show that for this example the algorithm selects a physically realistic set. Other tentative suggestions in the literature for set selection algorithms using ideas from information theory are discussed.
Maximum process problems in optimal control theory
Goran Peskir
2005-01-01
Full Text Available Given a standard Brownian motion (Btt≥0 and the equation of motion dXt=vtdt+2dBt, we set St=max0≤s≤tXs and consider the optimal control problem supvE(Sτ−Cτ, where c>0 and the supremum is taken over all admissible controls v satisfying vt∈[μ0,μ1] for all t up to τ=inf{t>0|Xt∉(ℓ0,ℓ1} with μ0g∗(St, where s↦g∗(s is a switching curve that is determined explicitly (as the unique solution to a nonlinear differential equation. The solution found demonstrates that the problem formulations based on a maximum functional can be successfully included in optimal control theory (calculus of variations in addition to the classic problem formulations due to Lagrange, Mayer, and Bolza.
Maximum Spectral Luminous Efficacy of White Light
Murphy, T W
2013-01-01
As lighting efficiency improves, it is useful to understand the theoretical limits to luminous efficacy for light that we perceive as white. Independent of the efficiency with which photons are generated, there exists a spectrally-imposed limit to the luminous efficacy of any source of photons. We find that, depending on the acceptable bandpass and---to a lesser extent---the color temperature of the light, the ideal white light source achieves a spectral luminous efficacy of 250--370 lm/W. This is consistent with previous calculations, but here we explore the maximum luminous efficacy as a function of photopic sensitivity threshold, color temperature, and color rendering index; deriving peak performance as a function of all three parameters. We also present example experimental spectra from a variety of light sources, quantifying the intrinsic efficacy of their spectral distributions.
Maximum entropy model for business cycle synchronization
Xi, Ning; Muneepeerakul, Rachata; Azaele, Sandro; Wang, Yougui
2014-11-01
The global economy is a complex dynamical system, whose cyclical fluctuations can mainly be characterized by simultaneous recessions or expansions of major economies. Thus, the researches on the synchronization phenomenon are key to understanding and controlling the dynamics of the global economy. Based on a pairwise maximum entropy model, we analyze the business cycle synchronization of the G7 economic system. We obtain a pairwise-interaction network, which exhibits certain clustering structure and accounts for 45% of the entire structure of the interactions within the G7 system. We also find that the pairwise interactions become increasingly inadequate in capturing the synchronization as the size of economic system grows. Thus, higher-order interactions must be taken into account when investigating behaviors of large economic systems.
Quantum gravity momentum representation and maximum energy
Moffat, J. W.
2016-11-01
We use the idea of the symmetry between the spacetime coordinates xμ and the energy-momentum pμ in quantum theory to construct a momentum space quantum gravity geometry with a metric sμν and a curvature tensor Pλ μνρ. For a closed maximally symmetric momentum space with a constant 3-curvature, the volume of the p-space admits a cutoff with an invariant maximum momentum a. A Wheeler-DeWitt-type wave equation is obtained in the momentum space representation. The vacuum energy density and the self-energy of a charged particle are shown to be finite, and modifications of the electromagnetic radiation density and the entropy density of a system of particles occur for high frequencies.
Video segmentation using Maximum Entropy Model
QIN Li-juan; ZHUANG Yue-ting; PAN Yun-he; WU Fei
2005-01-01
Detecting objects of interest from a video sequence is a fundamental and critical task in automated visual surveillance.Most current approaches only focus on discriminating moving objects by background subtraction whether or not the objects of interest can be moving or stationary. In this paper, we propose layers segmentation to detect both moving and stationary target objects from surveillance video. We extend the Maximum Entropy (ME) statistical model to segment layers with features, which are collected by constructing a codebook with a set of codewords for each pixel. We also indicate how the training models are used for the discrimination of target objects in surveillance video. Our experimental results are presented in terms of the success rate and the segmenting precision.
Maximum imaging depth of two-photon autofluorescence microscopy in epithelial tissues.
Durr, Nicholas J; Weisspfennig, Christian T; Holfeld, Benjamin A; Ben-Yakar, Adela
2011-02-01
Endogenous fluorescence provides morphological, spectral, and lifetime contrast that can indicate disease states in tissues. Previous studies have demonstrated that two-photon autofluorescence microscopy (2PAM) can be used for noninvasive, three-dimensional imaging of epithelial tissues down to approximately 150 μm beneath the skin surface. We report ex-vivo 2PAM images of epithelial tissue from a human tongue biopsy down to 370 μm below the surface. At greater than 320 μm deep, the fluorescence generated outside the focal volume degrades the image contrast to below one. We demonstrate that these imaging depths can be reached with 160 mW of laser power (2-nJ per pulse) from a conventional 80-MHz repetition rate ultrafast laser oscillator. To better understand the maximum imaging depths that we can achieve in epithelial tissues, we studied image contrast as a function of depth in tissue phantoms with a range of relevant optical properties. The phantom data agree well with the estimated contrast decays from time-resolved Monte Carlo simulations and show maximum imaging depths similar to that found in human biopsy results. This work demonstrates that the low staining inhomogeneity (∼ 20) and large scattering coefficient (∼ 10 mm(-1)) associated with conventional 2PAM limit the maximum imaging depth to 3 to 5 mean free scattering lengths deep in epithelial tissue.
Cosmic shear measurement with maximum likelihood and maximum a posteriori inference
Hall, Alex
2016-01-01
We investigate the problem of noise bias in maximum likelihood and maximum a posteriori estimators for cosmic shear. We derive the leading and next-to-leading order biases and compute them in the context of galaxy ellipticity measurements, extending previous work on maximum likelihood inference for weak lensing. We show that a large part of the bias on these point estimators can be removed using information already contained in the likelihood when a galaxy model is specified, without the need for external calibration. We test these bias-corrected estimators on simulated galaxy images similar to those expected from planned space-based weak lensing surveys, with very promising results. We find that the introduction of an intrinsic shape prior mitigates noise bias, such that the maximum a posteriori estimate can be made less biased than the maximum likelihood estimate. Second-order terms offer a check on the convergence of the estimators, but are largely sub-dominant. We show how biases propagate to shear estima...
Magnetic resonance perfusion imaging without contrast media
Martirosian, Petros; Graf, Hansjoerg; Schick, Fritz [University Hospital of Tuebingen, Section on Experimental Radiology, Tuebingen (Germany); Boss, Andreas; Schraml, Christina; Schwenzer, Nina F.; Claussen, Claus D. [University Hospital of Tuebingen, Department of Diagnostic and Interventional Radiology, Tuebingen (Germany)
2010-08-15
Principles of magnetic resonance imaging techniques providing perfusion-related contrast weighting without administration of contrast media are reported and analysed systematically. Especially common approaches to arterial spin labelling (ASL) perfusion imaging allowing quantitative assessment of specific perfusion rates are described in detail. The potential of ASL for perfusion imaging was tested in several types of tissue. After a systematic comparison of technical aspects of continuous and pulsed ASL techniques the standard kinetic model and tissue properties of influence to quantitative measurements of perfusion are reported. For the applications demonstrated in this paper a flow-sensitive alternating inversion recovery (FAIR) ASL perfusion preparation approach followed by true fast imaging with steady precession (true FISP) data recording was developed and implemented on whole-body scanners operating at 0.2, 1.5 and 3 T for quantitative perfusion measurement in various types of tissue. ASL imaging provides a non-invasive tool for assessment of tissue perfusion rates in vivo. Images recorded from kidney, lung, brain, salivary gland and thyroid gland provide a spatial resolution of a few millimetres and sufficient signal to noise ratio in perfusion maps after 2-5 min of examination time. Newly developed ASL techniques provide especially high image quality and quantitative perfusion maps in tissues with relatively high perfusion rates (as also present in many tumours). Averaging of acquisitions and image subtraction procedures are mandatory, leading to the necessity of synchronization of data recording to breathing in abdominal and thoracic organs. (orig.)
Improving photoacoustic imaging contrast of brachytherapy seeds
Pan, Leo; Baghani, Ali; Rohling, Robert; Abolmaesumi, Purang; Salcudean, Septimiu; Tang, Shuo
2013-03-01
Prostate brachytherapy is a form of radiotherapy for treating prostate cancer where the radiation sources are seeds inserted into the prostate. Accurate localization of seeds during prostate brachytherapy is essential to the success of intraoperative treatment planning. The current standard modality used in intraoperative seeds localization is transrectal ultrasound. Transrectal ultrasound, however, suffers in image quality due to several factors such speckle, shadowing, and off-axis seed orientation. Photoacoustic imaging, based on the photoacoustic phenomenon, is an emerging imaging modality. The contrast generating mechanism in photoacoustic imaging is optical absorption that is fundamentally different from conventional B-mode ultrasound which depicts changes in acoustic impedance. A photoacoustic imaging system is developed using a commercial ultrasound system. To improve imaging contrast and depth penetration, absorption enhancing coating is applied to the seeds. In comparison to bare seeds, approximately 18.5 dB increase in signal-to-noise ratio as well as a doubling of imaging depth are achieved. Our results demonstrate that the coating of the seeds can further improve the discernibility of the seeds.
Synthesis of Laboratory Ultrasound Contrast Agents
Jaemin Oh
2013-10-01
Full Text Available Ultrasound Contrast Agents (UCAs were developed to maximize reflection contrast so that organs can be seen clearly in ultrasound imaging. UCAs increase the signal to noise ratio (SNR by linear and non-linear mechanisms and thus help more accurately visualize the internal organs and blood vessels. However, the UCAs on the market are not only expensive, but are also not optimized for use in various therapeutic research applications such as ultrasound-aided drug delivery. The UCAs fabricated in this study utilize conventional lipid and albumin for shell formation and perfluorobutane as the internal gas. The shape and density of the UCA bubbles were verified by optical microscopy and Cryo SEM, and compared to those of the commercially available UCAs, Definity® and Sonovue®. The size distribution and characteristics of the reflected signal were also analyzed using a particle size analyzer and ultrasound imaging equipment. Our experiments indicate that UCAs composed of spherical microbubbles, the majority of which were smaller than 1 um, were successfully synthesized. Microbubbles 10 um or larger were also identified when different shell characteristics and filters were used. These laboratory UCAs can be used for research in both diagnoses and therapies.
Odds Ratios Estimation of Rare Event in Binomial Distribution
Kobkun Raweesawat
2016-01-01
Full Text Available We introduce the new estimator of odds ratios in rare events using Empirical Bayes method in two independent binomial distributions. We compare the proposed estimates of odds ratios with two estimators, modified maximum likelihood estimator (MMLE and modified median unbiased estimator (MMUE, using the Estimated Relative Error (ERE as a criterion of comparison. It is found that the new estimator is more efficient when compared to the other methods.
Lantam Sonhaye
2015-01-01
Full Text Available The goal of this study was to assess risk for CIN after CT Scan during an emergency and to identify risk factors for the patient. Prospective review of all patients admitted to the emergency room (ER of the Teaching Hospital of Lomé (Togo during a 2-year period. CIN was defined as an increase in serum creatinine by 0.5 mg/dL from admission after undergoing CT Scan with intravenous contrast. A total of 620 patients underwent a CT Scan in the emergency room using intravenous contrast and 672 patients took the CT Scan without intravenous contrast. Out of the patients who received intravenous contrast for CT Scan, three percent of them developed CIN during their admission. Moreover, upon discharge no patient had continued renal impairment. No patient required dialysis during their admission. The multivariate analysis of all patients who had serial creatinine levels (including those who did not receive any contrast load shows no increased risk for acute kidney injury associated intravenous contrast (odds ratio = 0.619, p value = 0.886; only diabetes remains independent risk factor of acute kidney injury (odds ratio = 6.26, p value = 0.031.
Baker, K; Silva, D; Poyneer, L; Macintosh, B; Bauman, B; Palmer, D; Remington, T; Delgadillo-Lariz, M
2008-01-23
Several high-contrast imaging systems are currently under construction to enable the detection of extra-solar planets. In order for these systems to achieve their objectives, however, there is considerable developmental work and testing which must take place. Given the need to perform these tests, a spatially-filtered Shack-Hartmann adaptive optics system has been assembled to evaluate new algorithms and hardware configurations which will be implemented in these future high-contrast imaging systems. In this article, construction and phase measurements of a membrane 'woofer' mirror are presented. In addition, results from closed-loop operation of the assembled testbed with static phase plates are presented. The testbed is currently being upgraded to enable operation at speeds approaching 500 hz and to enable studies of the interactions between the woofer and tweeter deformable mirrors.
Osmolality of nonionic contrast media.
Miklautz, H; Fichte, K; Wegscheider, K
1989-01-01
Solutions of different low osmolar contrast media (CM) obviously show clinically relevant differences in the osmolality despite equal iodine concentrations and similar molecular structure. To obtain precise and comparable data, the osmolality of five batches (usually) each of contrast media, iopamidol, iohexol, iopromide, and ioxaglate-all preparations commercially available-were measured by means of the vapor pressure method. The osmolality of the solutions of sodium meglumine ioxaglate with the same iodine concentration is lower than that of the nonionic CM examined. Iopromide showed the lowest osmolality and iohexol the highest value of the nonionic preparations. The differences are statistically significant as a rule. They are attributed to a varying association and hydration of the CM molecules in the solution.
Borkowski, Robert; Johannisson, Pontus; Wymeersch, Henk;
2014-01-01
We perform an experimental investigation of a maximum likelihood-based (ML-based) algorithm for bulk chromatic dispersion estimation for digital coherent receivers operating in uncompensated optical networks. We demonstrate the robustness of the method at low optical signal-to-noise ratio (OSNR) ...
Lower bounds on the maximum energy benefit of network coding for wireless multiple unicast
Goseling, Jasper; Matsumoto, Ryutaroh; Uyematsu, Tomohiko; Weber, Jos H.
2010-01-01
We consider the energy savings that can be obtained by employing network coding instead of plain routing in wireless multiple unicast problems. We establish lower bounds on the benefit of network coding, defined as the maximum of the ratio of the minimum energy required by routing and network coding
Lower bounds on the maximum energy benefit of network coding for wireless multiple unicast
Goseling, Jasper; Matsumoto, Ryutaroh; Uyematsu, Tomohiko; Weber, Jos H.
2010-01-01
We consider the energy savings that can be obtained by employing network coding instead of plain routing in wireless multiple unicast problems. We establish lower bounds on the benefit of network coding, defined as the maximum of the ratio of the minimum energy required by routing and network coding
Molecular clock fork phylogenies: closed form analytic maximum likelihood solutions.
Chor, Benny; Snir, Sagi
2004-12-01
Maximum likelihood (ML) is increasingly used as an optimality criterion for selecting evolutionary trees, but finding the global optimum is a hard computational task. Because no general analytic solution is known, numeric techniques such as hill climbing or expectation maximization (EM) are used in order to find optimal parameters for a given tree. So far, analytic solutions were derived only for the simplest model-three-taxa, two-state characters, under a molecular clock. Quoting Ziheng Yang, who initiated the analytic approach,"this seems to be the simplest case, but has many of the conceptual and statistical complexities involved in phylogenetic estimation."In this work, we give general analytic solutions for a family of trees with four-taxa, two-state characters, under a molecular clock. The change from three to four taxa incurs a major increase in the complexity of the underlying algebraic system, and requires novel techniques and approaches. We start by presenting the general maximum likelihood problem on phylogenetic trees as a constrained optimization problem, and the resulting system of polynomial equations. In full generality, it is infeasible to solve this system, therefore specialized tools for the molecular clock case are developed. Four-taxa rooted trees have two topologies-the fork (two subtrees with two leaves each) and the comb (one subtree with three leaves, the other with a single leaf). We combine the ultrametric properties of molecular clock fork trees with the Hadamard conjugation to derive a number of topology dependent identities. Employing these identities, we substantially simplify the system of polynomial equations for the fork. We finally employ symbolic algebra software to obtain closed formanalytic solutions (expressed parametrically in the input data). In general, four-taxa trees can have multiple ML points. In contrast, we can now prove that each fork topology has a unique(local and global) ML point.
Contrast-enhanced digital mammography
Dromain, Clarisse [Department of Radiology, Institut Gustave-Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex (France)], E-mail: dromain@igr.fr; Balleyguier, Corinne; Adler, Ghazal [Department of Radiology, Institut Gustave-Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex (France); Garbay, Jean Remi [Department of Surgery, Institut Gustave-Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex (France); Delaloge, Suzette [Department of Medicine, Institut Gustave-Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex (France)
2009-01-15
CEDM is a recent development of digital mammography using the intra-venous injection of an iodinated contrast agent in conjunction with a mammography examination. Two techniques have been developed to perform CEDM examinations: the temporal subtraction technique with acquisition of high-energy images before and after contrast medium injection and the dual energy technique with acquisition of a pair of low and high-energy images only after contrast medium injection. The temporal subtraction technique offered the possibility to analyze the kinetic curve of enhancement of breast lesions, similarly to breast MRI. The dual energy technique do not provide information about the kinetic of tumor enhancement but allows the acquisition of multiples views of the same breast or bilateral examination and is less sensitive to patient motion than temporal CEDM. Initial clinical experience has shown the ability of CEDM to map the distribution of neovasculature induced by cancer using mammography. Moreover, previous studies have shown a superiority of MX + CEDM, either for the assessment of the probability of malignancy than for BIRADS assessment comparing to MX alone. The potential clinical applications are the clarification of mammographically equivocal lesions, the detection of occult lesions on standard mammography, particularly in dense breast, the determination of the extent of disease, the assessment of recurrent disease and the monitoring of the response to chemotherapy. CEDM should result in a simple way to enhance the detection and the characterization of breast lesions.
Electrofluidic systems for contrast management
Rebello, Keith J.; Maranchi, Jeffrey P.; Tiffany, Jason E.; Brown, Christopher Y.; Maisano, Adam J.; Hagedon, Matthew A.; Heikenfeld, Jason C.
2012-06-01
Operating in dynamic lighting conditions and in greatly varying backgrounds is challenging. Current paints and state-ofthe- art passive adaptive coatings (e.g. photochromics) are not suitable for multi- environment situations. A semi-active, low power, skin is needed that can adapt its reflective properties based on the background environment to minimize contrast through the development and incorporation of suitable pigment materials. Electrofluidic skins are a reflective display technology for electronic ink and paper applications. The technology is similar to that in E Ink but makes use of MEMS based microfluidic structures, instead of simple black and white ink microcapsules dispersed in clear oil. Electrofluidic skin's low power operation and fast switching speeds (~20 ms) are an improvement over current state-ofthe- art contrast management technologies. We report on a microfluidic display which utilizes diffuse pigment dispersion inks to change the contrast of the underlying substrate from 5.8% to 100%. Voltage is applied and an electromechanical pressure is used to pull a pigment dispersion based ink from a hydrophobic coated reservoir into a hydrophobic coated surface channel. When no voltage is applied, the Young-Laplace pressure pushes the pigment dispersion ink back down into the reservoir. This allows the pixel to switch from the on and off state by balancing the two pressures. Taking a systems engineering approach from the beginning of development has enabled the technology to be integrated into larger systems.
Airapetian, A. [Justus-Liebig Universitaet Giessen, II. Physikalisches Institut, Giessen (Germany); University of Michigan, Randall Laboratory of Physics, Ann Arbor, MI (United States); Akopov, N.; Elbakian, G.; Gharibyan, V.; Marukyan, H.; Petrosyan, A. [Yerevan Physics Institute, Yerevan (Armenia); Akopov, Z.; Borissov, A.; Deconinck, W.; Holler, Y.; Rostomyan, A.; Zihlmann, B. [DESY, Hamburg (Germany); Aschenauer, E.C.; Nowak, W.D. [DESY, Zeuthen (Germany); Augustyniak, W.; Marianski, B.; Trzcinski, A.; Zupranski, P. [National Centre for Nuclear Research, Warsaw (Poland); Belostotski, S.; Kisselev, A.; Manaenkov, S.I.; Veretennikov, D.; Vikhrov, V. [B.P. Konstantinov Petersburg Nuclear Physics Institute, Leningrad Region (Russian Federation); Blok, H.P. [National Institute for Subatomic Physics (Nikhef), Amsterdam (Netherlands); VU University, Department of Physics and Astronomy, Amsterdam (Netherlands); Bryzgalov, V.; Ivanilov, A.; Korotkov, V.; Salomatin, Y. [Institute for High Energy Physics, Moscow Region (Russian Federation); Capitani, G.P.; De Sanctis, E.; Muccifora, V.; Reolon, A.R. [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali di Frascati, Frascati (Italy); Ciullo, G.; Lenisa, P.; Pappalardo, L.L.; Statera, M. [Istituto Nazionale di Fisica Nucleare, Sezione di Ferrara, Ferrara (Italy); Universita di Ferrara, Dipartimento di Fisica e Scienze della Terra, Ferrara (Italy); Contalbrigo, M. [Istituto Nazionale di Fisica Nucleare, Sezione di Ferrara, Ferrara (Italy); De Leo, R.; Lagamba, L.; Vilardi, I. [Istituto Nazionale di Fisica Nucleare, Sezione di Bari, Bari (Italy); Dueren, M. [Justus-Liebig Universitaet Giessen, II. Physikalisches Institut, Giessen (Germany); Ellinghaus, F. [University of Colorado, Nuclear Physics Laboratory, Boulder, CO (United States); Felawka, L. [TRIUMF, Vancouver, BC (Canada); Frullani, S.; Garibaldi, F. [Istituto Nazionale di Fisica Nucleare, Sezione di Roma, Gruppo Collegato Sanita, Rome (Italy); Istituto Superiore di Sanita, Rome (Italy); Gavrilov, G. [DESY, Hamburg (Germany); B.P. Konstantinov Petersburg Nuclear Physics Institute, Leningrad Region (Russian Federation); TRIUMF, Vancouver, BC (Canada); Goloskokov, S.V.; Shutov, V. [Joint Institute for Nuclear Research, Dubna (Russian Federation); Jackson, H.E.; Reimer, P.E. [Argonne National Laboratory, Physics Division, Argonne, IL (United States); Joosten, S. [Ghent University, Department of Physics and Astronomy, Gent (Belgium); University of Illinois, Department of Physics, Urbana, IL (United States); Kaiser, R.; Lehmann, I.; Rosner, G.; Seitz, B. [University of Glasgow, SUPA, School of Physics and Astronomy, Glasgow (United Kingdom); Karyan, G. [DESY, Hamburg (Germany); Yerevan Physics Institute, Yerevan (Armenia); Kozlov, V.; Terkulov, A. [Lebedev Physical Institute, Moscow (Russian Federation); Kravchenko, P. [Universitaet Erlangen-Nuernberg, Physikalisches Institut, Erlangen (Germany); B.P. Konstantinov Petersburg Nuclear Physics Institute, Leningrad Region (Russian Federation); Kroll, P.; Schaefer, A. [Universitaet Regensburg, Institut fuer Theoretische Physik, Regensburg (Germany); Lapikas, L. [National Institute for Subatomic Physics (Nikhef), Amsterdam (Netherlands); Lorenzon, W. [University of Michigan, Randall Laboratory of Physics, Ann Arbor, MI (United States); Miyachi, Y.; Shibata, T.A. [Tokyo Institute of Technology, Department of Physics, Tokyo (Japan); Movsisyan, A. [Istituto Nazionale di Fisica Nucleare, Sezione di Ferrara, Ferrara (Italy); Yerevan Physics Institute, Yerevan (Armenia); Nass, A.; Rith, K. [Universitaet Erlangen-Nuernberg, Physikalisches Institut, Erlangen (Germany); Riedl, C. [DESY, Zeuthen (Germany); University of Illinois, Department of Physics, Urbana, IL (United States); Ryckbosch, D.; Tytgat, M.; Haarlem, Y. van [Ghent University, Department of Physics and Astronomy, Gent (Belgium); Schnell, G. [University of the Basque Country UPV/EHU, Department of Theoretical Physics, Bilbao (Spain); Basque Foundation for Science, IKERBASQUE, Bilbao (Spain); Ghent University, Department of Physics and Astronomy, Gent (Belgium); Truty, R. [University of Illinois, Department of Physics, Urbana, IL (United States)
2017-06-15
Exclusive ρ{sup 0}-meson electroproduction is studied by the HERMES experiment, using the 27.6 GeV longitudinally polarized electron/positron beam of HERA and a transversely polarized hydrogen target, in the kinematic region 1.0 GeV{sup 2} < Q{sup 2} < 7.0 GeV{sup 2}, 3.0 GeV < W < 6.3 GeV, and -t{sup '} < 0.4 GeV{sup 2}. Using an unbinned maximum-likelihood method, 25 parameters are extracted. These determine the real and imaginary parts of the ratios of several helicity amplitudes describing ρ{sup 0}-meson production by a virtual photon. The denominator of those ratios is the dominant amplitude, the nucleon-helicity-non-flip amplitude F{sub 0(1)/(2)0(1)/(2)}, which describes the production of a longitudinal ρ{sup 0}-meson by a longitudinal virtual photon. The ratios of nucleon-helicity-non-flip amplitudes are found to be in good agreement with those from the previous HERMES analysis. The transverse target polarization allows for the first time the extraction of ratios of a number of nucleon-helicity-flip amplitudes to F{sub 0(1)/(2)0(1)/(2)}. Results obtained in a handbag approach based on generalized parton distributions taking into account the contribution from pion exchange are found to be in good agreement with these ratios. Within the model, the data favor a positive sign for the π - ρ transition form factor. By also exploiting the longitudinal beam polarization, a total of 71 ρ{sup 0} spin-density matrix elements is determined from the extracted 25 parameters, in contrast to only 53 elements as directly determined in earlier analyses. (orig.)
Dave, Jaydev K; Forsberg, Flemming
2009-09-01
The aim of this study was to develop a novel automated motion compensation algorithm for producing cumulative maximum intensity (CMI) images from subharmonic imaging (SHI) of breast lesions. SHI is a nonlinear contrast-specific ultrasound imaging technique in which pulses are received at half the frequency of the transmitted pulses. A Logiq 9 scanner (GE Healthcare, Milwaukee, WI, USA) was modified to operate in grayscale SHI mode (transmitting/receiving at 4.4/2.2 MHz) and used to scan 14 women with 16 breast lesions. Manual CMI images were reconstructed by temporal maximum-intensity projection of pixels traced from the first frame to the last. In the new automated technique, the user selects a kernel in the first frame and the algorithm then uses the sum of absolute difference (SAD) technique to identify motion-induced displacements in the remaining frames. A reliability parameter was used to estimate the accuracy of the motion tracking based on the ratio of the minimum SAD to the average SAD. Two thresholds (the mean and 85% of the mean reliability parameter) were used to eliminate images plagued by excessive motion and/or noise. The automated algorithm was compared with the manual technique for computational time, correction of motion artifacts, removal of noisy frames and quality of the final image. The automated algorithm compensated for motion artifacts and noisy frames. The computational time was 2 min compared with 60-90 minutes for the manual method. The quality of the motion-compensated CMI-SHI images generated by the automated technique was comparable to the manual method and provided a snapshot of the microvasculature showing interconnections between vessels, which was less evident in the original data. In conclusion, an automated algorithm for producing CMI-SHI images has been developed. It eliminates the need for manual processing and yields reproducible images, thereby increasing the throughput and efficiency of reconstructing CMI-SHI images. The
Tielbeek, Jeroen A.W.; Ziech, Manon L.W.; Lavini, Cristina; Bipat, Shandra; Stoker, Jaap [University of Amsterdam, Academic Medical Center, Department of Radiology, Amsterdam (Netherlands); Li, Zhang [Delft University of Technology, Quantitative Imaging Group, Department of Imaging Science and Technology, Delft (Netherlands); Bemelman, Willem A. [University of Amsterdam, Academic Medical Center, Department of Surgery, Amsterdam (Netherlands); Roelofs, Joris J.T.H. [University of Amsterdam, Academic Medical Center, Department of Pathology, Amsterdam (Netherlands); Ponsioen, Cyriel Y. [University of Amsterdam, Academic Medical Center, Department of Gastroenterology and Hepatology, Amsterdam (Netherlands); Vos, Frans M. [University of Amsterdam, Academic Medical Center, Department of Radiology, Amsterdam (Netherlands); Delft University of Technology, Quantitative Imaging Group, Department of Imaging Science and Technology, Delft (Netherlands)
2014-03-15
To prospectively compare conventional MRI sequences, dynamic contrast enhanced (DCE) MRI and diffusion weighted imaging (DWI) with histopathology of surgical specimens in Crohn's disease. 3-T MR enterography was performed in consecutive Crohn's disease patients scheduled for surgery within 4 weeks. One to four sections of interest per patient were chosen for analysis. Evaluated parameters included mural thickness, T1 ratio, T2 ratio; on DCE-MRI maximum enhancement (ME), initial slope of increase (ISI), time-to-peak (TTP); and on DWI apparent diffusion coefficient (ADC). These were compared with location-matched histopathological grading of inflammation (AIS) and fibrosis (FS) using Spearman correlation, Kruskal-Wallis and Chi-squared tests. Twenty patients (mean age 38 years, 12 female) were included and 50 sections (35 terminal ileum, 11 ascending colon, 2 transverse colon, 2 descending colon) were matched to AIS and FS. Mural thickness, T1 ratio, T2 ratio, ME and ISI correlated significantly with AIS, with moderate correlation (r = 0.634, 0.392, 0.485, 0.509, 0.525, respectively; all P < 0.05). Mural thickness, T1 ratio, T2 ratio, ME, ISI and ADC correlated significantly with FS (all P < 0.05). Quantitative parameters from conventional, DCE-MRI and DWI sequences correlate with histopathological scores of surgical specimens. DCE-MRI and DWI parameters provide additional information. (orig.)
20 CFR 211.14 - Maximum creditable compensation.
2010-04-01
... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Maximum creditable compensation. 211.14... CREDITABLE RAILROAD COMPENSATION § 211.14 Maximum creditable compensation. Maximum creditable compensation... Employment Accounts shall notify each employer of the amount of maximum creditable compensation applicable...
49 CFR 230.24 - Maximum allowable stress.
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Maximum allowable stress. 230.24 Section 230.24... Allowable Stress § 230.24 Maximum allowable stress. (a) Maximum allowable stress value. The maximum allowable stress value on any component of a steam locomotive boiler shall not exceed 1/4 of the ultimate...
Proposed principles of maximum local entropy production.
Ross, John; Corlan, Alexandru D; Müller, Stefan C
2012-07-12
Articles have appeared that rely on the application of some form of "maximum local entropy production principle" (MEPP). This is usually an optimization principle that is supposed to compensate for the lack of structural information and measurements about complex systems, even systems as complex and as little characterized as the whole biosphere or the atmosphere of the Earth or even of less known bodies in the solar system. We select a number of claims from a few well-known papers that advocate this principle and we show that they are in error with the help of simple examples of well-known chemical and physical systems. These erroneous interpretations can be attributed to ignoring well-established and verified theoretical results such as (1) entropy does not necessarily increase in nonisolated systems, such as "local" subsystems; (2) macroscopic systems, as described by classical physics, are in general intrinsically deterministic-there are no "choices" in their evolution to be selected by using supplementary principles; (3) macroscopic deterministic systems are predictable to the extent to which their state and structure is sufficiently well-known; usually they are not sufficiently known, and probabilistic methods need to be employed for their prediction; and (4) there is no causal relationship between the thermodynamic constraints and the kinetics of reaction systems. In conclusion, any predictions based on MEPP-like principles should not be considered scientifically founded.
Maximum entropy production and plant optimization theories.
Dewar, Roderick C
2010-05-12
Plant ecologists have proposed a variety of optimization theories to explain the adaptive behaviour and evolution of plants from the perspective of natural selection ('survival of the fittest'). Optimization theories identify some objective function--such as shoot or canopy photosynthesis, or growth rate--which is maximized with respect to one or more plant functional traits. However, the link between these objective functions and individual plant fitness is seldom quantified and there remains some uncertainty about the most appropriate choice of objective function to use. Here, plants are viewed from an alternative thermodynamic perspective, as members of a wider class of non-equilibrium systems for which maximum entropy production (MEP) has been proposed as a common theoretical principle. I show how MEP unifies different plant optimization theories that have been proposed previously on the basis of ad hoc measures of individual fitness--the different objective functions of these theories emerge as examples of entropy production on different spatio-temporal scales. The proposed statistical explanation of MEP, that states of MEP are by far the most probable ones, suggests a new and extended paradigm for biological evolution--'survival of the likeliest'--which applies from biomacromolecules to ecosystems, not just to individuals.
Maximum likelihood continuity mapping for fraud detection
Hogden, J.
1997-05-01
The author describes a novel time-series analysis technique called maximum likelihood continuity mapping (MALCOM), and focuses on one application of MALCOM: detecting fraud in medical insurance claims. Given a training data set composed of typical sequences, MALCOM creates a stochastic model of sequence generation, called a continuity map (CM). A CM maximizes the probability of sequences in the training set given the model constraints, CMs can be used to estimate the likelihood of sequences not found in the training set, enabling anomaly detection and sequence prediction--important aspects of data mining. Since MALCOM can be used on sequences of categorical data (e.g., sequences of words) as well as real valued data, MALCOM is also a potential replacement for database search tools such as N-gram analysis. In a recent experiment, MALCOM was used to evaluate the likelihood of patient medical histories, where ``medical history`` is used to mean the sequence of medical procedures performed on a patient. Physicians whose patients had anomalous medical histories (according to MALCOM) were evaluated for fraud by an independent agency. Of the small sample (12 physicians) that has been evaluated, 92% have been determined fraudulent or abusive. Despite the small sample, these results are encouraging.
CORA - emission line fitting with Maximum Likelihood
Ness, J.-U.; Wichmann, R.
2002-07-01
The advent of pipeline-processed data both from space- and ground-based observatories often disposes of the need of full-fledged data reduction software with its associated steep learning curve. In many cases, a simple tool doing just one task, and doing it right, is all one wishes. In this spirit we introduce CORA, a line fitting tool based on the maximum likelihood technique, which has been developed for the analysis of emission line spectra with low count numbers and has successfully been used in several publications. CORA uses a rigorous application of Poisson statistics. From the assumption of Poissonian noise we derive the probability for a model of the emission line spectrum to represent the measured spectrum. The likelihood function is used as a criterion for optimizing the parameters of the theoretical spectrum and a fixed point equation is derived allowing an efficient way to obtain line fluxes. As an example we demonstrate the functionality of the program with an X-ray spectrum of Capella obtained with the Low Energy Transmission Grating Spectrometer (LETGS) on board the Chandra observatory and choose the analysis of the Ne IX triplet around 13.5 Å.
Finding maximum JPEG image block code size
Lakhani, Gopal
2012-07-01
We present a study of JPEG baseline coding. It aims to determine the minimum storage needed to buffer the JPEG Huffman code bits of 8-bit image blocks. Since DC is coded separately, and the encoder represents each AC coefficient by a pair of run-length/AC coefficient level, the net problem is to perform an efficient search for the optimal run-level pair sequence. We formulate it as a two-dimensional, nonlinear, integer programming problem and solve it using a branch-and-bound based search method. We derive two types of constraints to prune the search space. The first one is given as an upper-bound for the sum of squares of AC coefficients of a block, and it is used to discard sequences that cannot represent valid DCT blocks. The second type constraints are based on some interesting properties of the Huffman code table, and these are used to prune sequences that cannot be part of optimal solutions. Our main result is that if the default JPEG compression setting is used, space of minimum of 346 bits and maximum of 433 bits is sufficient to buffer the AC code bits of 8-bit image blocks. Our implementation also pruned the search space extremely well; the first constraint reduced the initial search space of 4 nodes down to less than 2 nodes, and the second set of constraints reduced it further by 97.8%.
Maximum likelihood estimates of pairwise rearrangement distances.
Serdoz, Stuart; Egri-Nagy, Attila; Sumner, Jeremy; Holland, Barbara R; Jarvis, Peter D; Tanaka, Mark M; Francis, Andrew R
2017-06-21
Accurate estimation of evolutionary distances between taxa is important for many phylogenetic reconstruction methods. Distances can be estimated using a range of different evolutionary models, from single nucleotide polymorphisms to large-scale genome rearrangements. Corresponding corrections for genome rearrangement distances fall into 3 categories: Empirical computational studies, Bayesian/MCMC approaches, and combinatorial approaches. Here, we introduce a maximum likelihood estimator for the inversion distance between a pair of genomes, using a group-theoretic approach to modelling inversions introduced recently. This MLE functions as a corrected distance: in particular, we show that because of the way sequences of inversions interact with each other, it is quite possible for minimal distance and MLE distance to differently order the distances of two genomes from a third. The second aspect tackles the problem of accounting for the symmetries of circular arrangements. While, generally, a frame of reference is locked, and all computation made accordingly, this work incorporates the action of the dihedral group so that distance estimates are free from any a priori frame of reference. The philosophy of accounting for symmetries can be applied to any existing correction method, for which examples are offered. Copyright © 2017 Elsevier Ltd. All rights reserved.
Boedeker, Peter
2017-01-01
Hierarchical linear modeling (HLM) is a useful tool when analyzing data collected from groups. There are many decisions to be made when constructing and estimating a model in HLM including which estimation technique to use. Three of the estimation techniques available when analyzing data with HLM are maximum likelihood, restricted maximum…
Maximum Entropy Principle Based Estimation of Performance Distribution in Queueing Theory
He, Dayi; Li, Ran; Huang, Qi; Lei, Ping
2014-01-01
In related research on queuing systems, in order to determine the system state, there is a widespread practice to assume that the system is stable and that distributions of the customer arrival ratio and service ratio are known information. In this study, the queuing system is looked at as a black box without any assumptions on the distribution of the arrival and service ratios and only keeping the assumption on the stability of the queuing system. By applying the principle of maximum entropy, the performance distribution of queuing systems is derived from some easily accessible indexes, such as the capacity of the system, the mean number of customers in the system, and the mean utilization of the servers. Some special cases are modeled and their performance distributions are derived. Using the chi-square goodness of fit test, the accuracy and generality for practical purposes of the principle of maximum entropy approach is demonstrated. PMID:25207992
Maximum initial growth-rate of strong-shock-driven Richtmyer-Meshkov instability
Dell, Z. R.; Pandian, A.; Bhowmick, A. K.; Swisher, N. C.; Stanic, M.; Stellingwerf, R. F.; Abarzhi, S. I.
2017-09-01
We focus on the classical problem of the dependence on the initial conditions of the initial growth-rate of strong shock driven Richtmyer-Meshkov instability (RMI) by developing a novel empirical model and by employing rigorous theories and Smoothed Particle Hydrodynamics simulations to describe the simulation data with statistical confidence in a broad parameter regime. For the given values of the shock strength, fluid density ratio, and wavelength of the initial perturbation of the fluid interface, we find the maximum value of the RMI initial growth-rate, the corresponding amplitude scale of the initial perturbation, and the maximum fraction of interfacial energy. This amplitude scale is independent of the shock strength and density ratio and is characteristic quantity of RMI dynamics. We discover the exponential decay of the ratio of the initial and linear growth-rates of RMI with the initial perturbation amplitude that excellently agrees with available data.
Maximum entropy principle based estimation of performance distribution in queueing theory.
He, Dayi; Li, Ran; Huang, Qi; Lei, Ping
2014-01-01
In related research on queuing systems, in order to determine the system state, there is a widespread practice to assume that the system is stable and that distributions of the customer arrival ratio and service ratio are known information. In this study, the queuing system is looked at as a black box without any assumptions on the distribution of the arrival and service ratios and only keeping the assumption on the stability of the queuing system. By applying the principle of maximum entropy, the performance distribution of queuing systems is derived from some easily accessible indexes, such as the capacity of the system, the mean number of customers in the system, and the mean utilization of the servers. Some special cases are modeled and their performance distributions are derived. Using the chi-square goodness of fit test, the accuracy and generality for practical purposes of the principle of maximum entropy approach is demonstrated.
Maximum entropy principle based estimation of performance distribution in queueing theory.
Dayi He
Full Text Available In related research on queuing systems, in order to determine the system state, there is a widespread practice to assume that the system is stable and that distributions of the customer arrival ratio and service ratio are known information. In this study, the queuing system is looked at as a black box without any assumptions on the distribution of the arrival and service ratios and only keeping the assumption on the stability of the queuing system. By applying the principle of maximum entropy, the performance distribution of queuing systems is derived from some easily accessible indexes, such as the capacity of the system, the mean number of customers in the system, and the mean utilization of the servers. Some special cases are modeled and their performance distributions are derived. Using the chi-square goodness of fit test, the accuracy and generality for practical purposes of the principle of maximum entropy approach is demonstrated.
Aspect ratio dependence in magnetorotational instability shearing box simulations
Bodo, G; Cattaneo, F; Rossi, P; Ferrari, A
2008-01-01
Aims: We study the changes in the properties of turbulence driven by the magnetorotational instability in a shearing box, as the computational domain size in the radial direction is varied relative to the height Methods: We perform 3D simulations in the shearing box approximation, with a net magnetic flux, and we consider computational domains with different aspect ratios Results: We find that in boxes of aspect ratio unity the transport of angular momentum is strongly intermittent and dominated by channel solutions in agreement with previous work. In contrast, in boxes with larger aspect ratio, the channel solutions and the associated intermittent behavior disappear. Conclusions: There is strong evidence that, as the aspect ratio becomes larger, the characteristics of the solution become aspect ratio independent. We conclude that shearing box calculations with aspect ratio unity or near unity may introduce spurious effects.
Efficient multi-keV X-ray generation from high-contrast laser plasma interaction
Zhang Z.
2013-11-01
Full Text Available Kα line emission from Mo was experimentally and theoretically studied using clean, ultrahigh-intensity femtosecond laser pulses. The absolute yields of Kα x-rays at 17 keV from Mo were measured as a function of the laser pulse contrast ratio and irradiation intensity. Significantly enhanced Kα yields were obtained by employing high contrast ratio at optimum irradiance. Conversion efficiencies of 4.28 × 10−5/sr, the highest values obtained to date, was demonstrated with contrast ratios in the range of 10−10 to 10−11.
Contrasting strategic and Milan therapies.
MacKinnon, L
1983-12-01
Three related models of therapy are often grouped together as the strategic therapies. These are brief therapy model associated with the Mental Research Institute, approaches developed by Jay Haley and Cloë Madanes, and the model developed by the Milan associates. Controversy exists, however, as to whether the Milan model should be included as a strategic therapy. It appears that the similarities among the three models can mask deeper differences, thus confounding the confusion. This paper contrast the models in their development, theory, and practice.
Document delivery services contrasting views
1999-01-01
Design and maintain document delivery services that are ideal for academic patrons! In Document Delivery Services: Contrasting Views, you'll visit four university library systems to discover the considerations and challenges each library faced in bringing document delivery to its clientele. This book examines the questions about document delivery that are most pressing in the profession of library science. Despite their own unique experiences, you'll find common practices among all four?including planning, implementation of service, and evaluation of either user satisfaction and/or vendor per
The Generalised Phase Contrast Method
Glückstad, Jesper
. Optimal conditions for visibility, peak irradiance and accuracy are derived and shown to be perfectly in line with empirical results from the literature. New graphic methods for advanced analysis purposes are demonstrated supporting these conclusions as well as providing new tools for innovative filter...... designs and parameter settings. Finally, a number of original applications facilitated by the parallel light-beam encoding of the Generalised Phase Contrast method are briefly outlined. These include among others, wavefront sensing and generation, advanced usercontrolled optical micro......-manipulation, optical phase-only encryption/decryption and fully integrated micro-optical implementations....
Sex Ratio Elasticity Influences the Selection of Sex Ratio Strategy
Wang, Yaqiang; Wang, Ruiwu; Li, Yaotang; (Sam) Ma, Zhanshan
2016-01-01
There are three sex ratio strategies (SRS) in nature—male-biased sex ratio, female-biased sex ratio and, equal sex ratio. It was R. A. Fisher who first explained why most species in nature display a sex ratio of ½. Consequent SRS theories such as Hamilton’s local mate competition (LMC) and Clark’s local resource competition (LRC) separately explained the observed deviations from the seemingly universal 1:1 ratio. However, to the best of our knowledge, there is not yet a unified theory that accounts for the mechanisms of the three SRS. Here, we introduce the price elasticity theory in economics to define sex ratio elasticity (SRE), and present an analytical model that derives three SRSs based on the following assumption: simultaneously existing competitions for both resources A and resources B influence the level of SRE in both sexes differently. Consequently, it is the difference (between two sexes) in the level of their sex ratio elasticity that leads to three different SRS. Our analytical results demonstrate that the elasticity-based model not only reveals a highly plausible mechanism that explains the evolution of SRS in nature, but also offers a novel framework for unifying two major classical theories (i.e., LMC & LRC) in the field of SRS research. PMID:28009000
Sex Ratio Elasticity Influences the Selection of Sex Ratio Strategy
Wang, Yaqiang; Wang, Ruiwu; Li, Yaotang; (Sam) Ma, Zhanshan
2016-12-01
There are three sex ratio strategies (SRS) in nature—male-biased sex ratio, female-biased sex ratio and, equal sex ratio. It was R. A. Fisher who first explained why most species in nature display a sex ratio of ½. Consequent SRS theories such as Hamilton’s local mate competition (LMC) and Clark’s local resource competition (LRC) separately explained the observed deviations from the seemingly universal 1:1 ratio. However, to the best of our knowledge, there is not yet a unified theory that accounts for the mechanisms of the three SRS. Here, we introduce the price elasticity theory in economics to define sex ratio elasticity (SRE), and present an analytical model that derives three SRSs based on the following assumption: simultaneously existing competitions for both resources A and resources B influence the level of SRE in both sexes differently. Consequently, it is the difference (between two sexes) in the level of their sex ratio elasticity that leads to three different SRS. Our analytical results demonstrate that the elasticity-based model not only reveals a highly plausible mechanism that explains the evolution of SRS in nature, but also offers a novel framework for unifying two major classical theories (i.e., LMC & LRC) in the field of SRS research.
Continuous maximum flow segmentation method for nanoparticle interaction analysis.
Marak, L; Tankyevych, O; Talbot, H
2011-10-01
In recent years, tomographic three-dimensional reconstruction approaches using electrons rather than X-rays have become popular. Such images produced with a transmission electron microscope make it possible to image nanometre-scale materials in three-dimensional. However, they are also noisy, limited in contrast and most often have a very poor resolution along the axis of the electron beam. The analysis of images stemming from such modalities, whether fully or semiautomated, is therefore more complicated. In particular, segmentation of objects is difficult. In this paper, we propose to use the continuous maximum flow segmentation method based on a globally optimal minimal surface model. The use of this fully automated segmentation and filtering procedure is illustrated on two different nanoparticle samples and provide comparisons with other classical segmentation methods. The main objectives are the measurement of the attraction rate of polystyrene beads to silica nanoparticle (for the first sample) and interaction of silica nanoparticles with large unilamellar liposomes (for the second sample). We also illustrate how precise measurements such as contact angles can be performed.
Multilayer coated gratings for phase-contrast computed tomography (CT)
Marton, Zsolt; Bhandari, Harish B.; Wen, Harold H.; Nagarkar, Vivek V.
2014-03-01
By using the principle of grating interferometry, X-ray phase contrast imaging can now be performed with incoherent radiation from standard X-ray tube. This approach is in stark contrast with imaging methods using coherent synchrotron X-ray sources or micro-focus sources to improve contrast. The gratings interferometer imaging technique is capable of measuring the phase shift of hard X-rays travelling through a sample, which greatly enhances the contrast of low absorbing specimen compared to conventional amplitude contrast images. The key components in this approach are the gratings which consists of alternating layers of high and low Z (atomic number) materials fabricated with high aspect ratios. Here we report on a novel method of fabricating the grating structures using the technique of electron-beam (ebeam) thin film deposition. Alternating layers of silicon (Z=14) and tungsten (Z=74) were deposited, each measuring 100 nm each, on a specially designed echelle substrate, which resulted in an aspect ratio of ~100:1. Fabrication parameters related to the thin film deposition such as geometry, directionality, film adhesion, stress and the resulting scanning electron micrographs will be discussed in detail. Using e-beam method large-area gratings with precise multilayer coating thicknesses can be fabricated economically circumventing the expensive lithography steps.
Mitsouras, Dimitris; Vemula, Praveen Kumar; Yu, Peng; Tao, Ming; Nguyen, Binh T; Campagna, Christina M; Karp, Jeffrey M; Mulkern, Robert V; Ozaki, C Keith; Rybicki, Frank J
2011-01-01
An implantable MR contrast agent that can be covalently immobilized on tissue during surgery has been developed. The rationale is that a durable increase in tissue contrast using an implantable contrast agent can enhance postsurgical tissue differentiation using MRI. For small-vessel (e.g., vein graft) MRI, the direct benefit of such permanent "labeling" of the vessel wall by modification of its relaxation properties is to achieve more efficient imaging. This efficiency can be realized as either increased contrast leading to more accurate delineation of vessel wall and lesion tissue boundaries, or, faster imaging without penalizing contrast-to-noise ratio, or a combination thereof. We demonstrate, for the first time, stable long-term MRI enhancement using such an exogenous contrast mechanism based on immobilizing a modified diethylenetriaminepentaacetic acid gadolinium(3+) dihydrogen complex on a human vein using a covalent amide bond. Signal enhancement due to the covalently immobilized contrast agent is demonstrated for excised human vein specimens imaged at 3 T, and its long-term stability is demonstrated during a 4-month incubation period.
Optically measured microvascular blood flow contrast of malignant breast tumors.
Regine Choe
Full Text Available Microvascular blood flow contrast is an important hemodynamic and metabolic parameter with potential to enhance in vivo breast cancer detection and therapy monitoring. Here we report on non-invasive line-scan measurements of malignant breast tumors with a hand-held optical probe in the remission geometry. The probe employs diffuse correlation spectroscopy (DCS, a near-infrared optical method that quantifies deep tissue microvascular blood flow. Tumor-to-normal perfusion ratios are derived from thirty-two human subjects. Mean (95% confidence interval tumor-to-normal ratio using surrounding normal tissue was 2.25 (1.92-2.63; tumor-to-normal ratio using normal tissues at the corresponding tumor location in the contralateral breast was 2.27 (1.94-2.66, and using normal tissue in the contralateral breast was 2.27 (1.90-2.70. Thus, the mean tumor-to-normal ratios were significantly different from unity irrespective of the normal tissue chosen, implying that tumors have significantly higher blood flow than normal tissues. Therefore, the study demonstrates existence of breast cancer contrast in blood flow measured by DCS. The new, optically accessible cancer contrast holds potential for cancer detection and therapy monitoring applications, and it is likely to be especially useful when combined with diffuse optical spectroscopy/tomography.
Hyland, D. C.
1983-01-01
A stochastic structural control model is described. In contrast to the customary deterministic model, the stochastic minimum data/maximum entropy model directly incorporates the least possible a priori parameter information. The approach is to adopt this model as the basic design model, thus incorporating the effects of parameter uncertainty at a fundamental level, and design mean-square optimal controls (that is, choose the control law to minimize the average of a quadratic performance index over the parameter ensemble).
Maximum speeds and alpha angles of flowing avalanches
McClung, David; Gauer, Peter
2016-04-01
A flowing avalanche is one which initiates as a slab and, if consisting of dry snow, will be enveloped in a turbulent snow dust cloud once the speed reaches about 10 m/s. A flowing avalanche has a dense core of flowing material which dominates the dynamics by serving as the driving force for downslope motion. The flow thickness typically on the order of 1 -10 m which is on the order of about 1% of the length of the flowing mass. We have collected estimates of maximum frontal speed um (m/s) from 118 avalanche events. The analysis is given here with the aim of using the maximum speed scaled with some measure of the terrain scale over which the avalanches ran. We have chosen two measures for scaling, from McClung (1990), McClung and Schaerer (2006) and Gauer (2012). The two measures are the √H0-;√S0-- (total vertical drop; total path length traversed). Our data consist of 118 avalanches with H0 (m)estimated and 106 with S0 (m)estimated. Of these, we have 29 values with H0 (m),S0 (m)and um (m/s)estimated accurately with the avalanche speeds measured all or nearly all along the path. The remainder of the data set includes approximate estimates of um (m/s)from timing the avalanche motion over a known section of the path where approximate maximum speed is expected and with either H0or S0or both estimated. Our analysis consists of fitting the values of um/√H0--; um/√S0- to probability density functions (pdf) to estimate the exceedance probability for the scaled ratios. In general, we found the best fits for the larger data sets to fit a beta pdf and for the subset of 29, we found a shifted log-logistic (s l-l) pdf was best. Our determinations were as a result of fitting the values to 60 different pdfs considering five goodness-of-fit criteria: three goodness-of-fit statistics :K-S (Kolmogorov-Smirnov); A-D (Anderson-Darling) and C-S (Chi-squared) plus probability plots (P-P) and quantile plots (Q-Q). For less than 10% probability of exceedance the results show that
The Prediction of Maximum Amplitudes of Solar Cycles and the Maximum Amplitude of Solar Cycle 24
无
2002-01-01
We present a brief review of predictions of solar cycle maximum ampli-tude with a lead time of 2 years or more. It is pointed out that a precise predictionof the maximum amplitude with such a lead-time is still an open question despiteprogress made since the 1960s. A method of prediction using statistical character-istics of solar cycles is developed: the solar cycles are divided into two groups, ahigh rising velocity (HRV) group and a low rising velocity (LRV) group, dependingon the rising velocity in the ascending phase for a given duration of the ascendingphase. The amplitude of Solar Cycle 24 can be predicted after the start of thecycle using the formula derived in this paper. Now, about 5 years before the startof the cycle, we can make a preliminary prediction of 83.2-119.4 for its maximumamplitude.
Kokado, Satoshi; Sakuraba, Yuya; Tsunoda, Masakiyo
2016-10-01
We derive a simple relational expression between the spin polarization ratio of resistivity, Pρ, and the anisotropic magnetoresistance ratio Δρ/ρ, and that between the spin polarization ratio of the density of states at the Fermi energy, PDOS, and Δρ/ρ for nearly half-metallic ferromagnets. We find that Pρ and PDOS increase with increasing |Δρ/ρ| from 0 to a maximum value. In addition, we roughly estimate Pρ and PDOS for a Co2FeGa0.5Ge0.5 Heusler alloy by substituting its experimentally observed Δρ/ρ into the respective expressions.
Deriving aerosol scattering ratio using range-resolved lidar ratio
Reji K Dhaman; V Krishnakumar; V P Mahadevan Pillai; M Satyanarayana; K Raghunath
2014-02-01
The study on the optical characteristics of aerosol is carried out using the dual polarization lidar observations from the tropical inland station Gadanki (13.5°N, 79.2°E) for the period of observation during the year 2010. The summer and monsoon observation days show high scattering ratio at the tropical tropopause layer (TTL) and at the lower stratosphere region. The depolarization ratio is also high at this altitude due to the transport of particulates to the TTL layer by the active convection prevailing at the period. The study reveals more dependable values of scattering ratio that are seasonal and range-dependent.
MODEL PREDICTIVE CONTROL FOR PHOTOVOLTAIC STATION MAXIMUM POWER POINT TRACKING SYSTEM
I. Elzein
2015-01-01
Full Text Available The purpose of this paper is to present an alternative maximum power point tracking, MPPT, algorithm for a photovoltaic module, PVM, to produce the maximum power, Pmax, using the optimal duty ratio, D, for different types of converters and load matching.We present a state-based approach to the design of the maximum power point tracker for a stand-alone photovoltaic power generation system. The system under consideration consists of a solar array with nonlinear time-varying characteristics, a step-up converter with appropriate filter.The proposed algorithm has the advantages of maximizing the efficiency of the power utilization, can be integrated to other MPPT algorithms without affecting the PVM performance, is excellent for Real-Time applications and is a robust analytical method, different from the traditional MPPT algorithms which are more based on trial and error, or comparisons between present and past states. The procedure to calculate the optimal duty ratio for a buck, boost and buck-boost converters, to transfer the maximum power from a PVM to a load, is presented in the paper. Additionally, the existence and uniqueness of optimal internal impedance, to transfer the maximum power from a photovoltaic module using load matching, is proved.
Phillip M. Ligrani
1996-01-01
Full Text Available Experimental results are presented which describe the development and structure of flow downstream of a single row of holes with compound angle orientations producing film cooling at high blowing ratios. This film cooling configuration is important because similar arrangements are frequently employed on the first stage of rotating blades of operating gas turbine engines. With this configuration, holes are spaced 6d apart in the spanwise direction, with inclination angles of 24 degrees, and angles of orientation of 50.5 degrees. Blowing ratios range from 1.5 to 4.0 and the ratio of injectant to freestream density is near 1.0. Results show that spanwise averaged adiabatic effectiveness, spanwise-averaged iso-energetic Stanton number ratios, surveys of streamwise mean velocity, and surveys of injectant distributions change by important amounts as the blowing ratio increases. This is due to injectant lift-off from the test surface just downstream of the holes.
Parameter Estimation for an Electric Arc Furnace Model Using Maximum Likelihood
Jesser J. Marulanda-Durango
2012-12-01
Full Text Available In this paper, we present a methodology for estimating the parameters of a model for an electrical arc furnace, by using maximum likelihood estimation. Maximum likelihood estimation is one of the most employed methods for parameter estimation in practical settings. The model for the electrical arc furnace that we consider, takes into account the non-periodic and non-linear variations in the voltage-current characteristic. We use NETLAB, an open source MATLAB® toolbox, for solving a set of non-linear algebraic equations that relate all the parameters to be estimated. Results obtained through simulation of the model in PSCADTM, are contrasted against real measurements taken during the furnance's most critical operating point. We show how the model for the electrical arc furnace, with appropriate parameter tuning, captures with great detail the real voltage and current waveforms generated by the system. Results obtained show a maximum error of 5% for the current's root mean square error.
B-Spline potential function for maximum a-posteriori image reconstruction in fluorescence microscopy
Shilpa Dilipkumar
2015-03-01
Full Text Available An iterative image reconstruction technique employing B-Spline potential function in a Bayesian framework is proposed for fluorescence microscopy images. B-splines are piecewise polynomials with smooth transition, compact support and are the shortest polynomial splines. Incorporation of the B-spline potential function in the maximum-a-posteriori reconstruction technique resulted in improved contrast, enhanced resolution and substantial background reduction. The proposed technique is validated on simulated data as well as on the images acquired from fluorescence microscopes (widefield, confocal laser scanning fluorescence and super-resolution 4Pi microscopy. A comparative study of the proposed technique with the state-of-art maximum likelihood (ML and maximum-a-posteriori (MAP with quadratic potential function shows its superiority over the others. B-Spline MAP technique can find applications in several imaging modalities of fluorescence microscopy like selective plane illumination microscopy, localization microscopy and STED.
Madsen, Henrik; Pearson, Charles P.; Rosbjerg, Dan
1997-04-01
Two regional estimation schemes, based on, respectively, partial duration series (PDS) and annual maximum series (AMS), are compared. The PDS model assumes a generalized Pareto (GP) distribution for modeling threshold exceedances corresponding to a generalized extreme value (GEV) distribution for annual maxima. First, the accuracy of PDS/GP and AMS/GEV regional index-flood T-year event estimators are compared using Monte Carlo simulations. For estimation in typical regions assuming a realistic degree of heterogeneity, the PDS/GP index-flood model is more efficient. The regional PDS and AMS procedures are subsequently applied to flood records from 48 catchments in New Zealand. To identify homogeneous groupings of catchments, a split-sample regionalization approach based on catchment characteristics is adopted. The defined groups are more homogeneous for PDS data than for AMS data; a two-way grouping based on annual average rainfall is sufficient to attain homogeneity for PDS, whereas a further partitioning is necessary for AMS. In determination of the regional parent distribution using L- moment ratio diagrams, PDS data, in contrast to AMS data, provide an unambiguous interpretation, supporting a GP distribution.
Contrastive tone in Kalam Kohistani
Joan L.G. Baart
2004-01-01
Full Text Available It has been observed that tonal phenomena occur in quite a few Indo-Aryan languages in the northwestern corner of the South-Asian subcontinent. This paper presents a study of the tone system of one of these languages, Kalam Kohistani. After establishing that Kalam Kohistani has five contrastive surface tones—a high tone, a low tone, a rising tone, and two types of falling tone—I propose an analysis of these tones in terms of Autosegmental Phonology. Furthermore, some observations are made on the relation between aspiration and tone, and on the functional load of tone in Kalam Kohistani. Its relatively rich inventory of tones makes Kalam Kohistani, along with two of its close neighbors, stand out as unique among the Indo-Aryan languages.
Analog CMOS contrastive Hebbian networks
Schneider, Christian; Card, Howard
1992-09-01
CMOS VLSI circuits implementing an analog neural network with on-chip contrastive Hebbian learning and capacitive synaptic weight storage have been designed and fabricated. Weights are refreshed by periodic repetition of the training data. To evaluate circuit performance in a medium-sized system, these circuits were used to build a 132 synapse neural network. An adaptive neural system, such as the one described in this paper, can compensate for imperfections in the components from which it is constructed, and thus it is possible to build this type of system using simple, silicon area-efficient analog circuits. Because these analog VLSI circuits are far more compact than their digital counterparts, analog VLSI neural network implementations are potentially more efficient than digital ones.
The Method of Culture Contrast
Hasse, Cathrine; Trentemøller, Stine; Motzkau, Johanna
2009-01-01
the researcher's cultural background (i.e., emic categorisations) in the analysis of cross-cultural comparisons we suggest that the categorisations the researcher use in her tests and fieldwork descriptions are taken to be part of the research itself, rather than simply being an underlying (taken for granted......In this article, we suggest that research is a practical activity building on local category systems belonging specifically to research (etic categories) as well as categories belonging specifically to the national culture of the researcher (emic categories) (Pike 1967). Much cross-cultural......) framework on which the research is conducted. First we present a recent study of European universities as culturally diverse working places and we present an approach in which the researcher's emic and etic categorisations can be challenged when contrasted with each other (Hasse & Trentemøller 2008). Second...
Octopaminergic modulation of contrast sensitivity
Roel ede Haan
2012-08-01
Full Text Available Sensory systems adapt to prolonged stimulation by decreasing their response to prevailing stimulus conditions. Whereas visual motion adaptation has traditionally been studied in immobilized animals, recent work indicates that the animal’s behavioral state influences the response properties of higher-order motion vision-sensitive neurons. During insect flight octopamine is released, and pharmacological octopaminergic activation can induce a fictive locomotor state. In the insect optic ganglia, lobula plate tangential cells (LPTCs spatially pool input from local elementary motion detectors (EMDs that correlate luminosity changes from two spatially discrete inputs after delaying the signal from one. The LPTC velocity optimum thereby depends on the spatial separation of the inputs and on the EMD’s delay properties. Recently it was shown that behavioral activity increases the LPTC velocity optimum, with modeling suggesting this to originate in the EMD’s temporal delay filters. However, behavior induces an additional post-EMD effect: the LPTC membrane conductance increases in flying flies. To physiologically investigate the degree to which activity causes presynaptic and postsynaptic effects, we conducted intracellular recordings of Eristalis horizontal system neurons. We constructed contrast response functions before and after adaptation at different temporal frequencies, with and without the octopamine receptor agonist chlordimeform (CDM. We extracted three motion adaptation components, where two are likely generated presynaptically of the LPTCs, and one within them. We found that CDM affected the early, EMD associated contrast gain reduction, temporal frequency dependently. However, a CDM-induced change of the HS membrane conductance disappeared during and after visual stimulation. This suggests that physical activity mainly affects motion adaptation presynaptically of LPTCs, whereas post-EMD effects have a minimal effect.
The NFL Combine 40-Yard Dash: How Important is Maximum Velocity?
Clark, Kenneth P; Rieger, Randall H; Bruno, Richard F; Stearne, David J
2017-06-22
This investigation analyzed the sprint velocity profiles for athletes who completed the 40-yard (36.6m) dash at the 2016 NFL Combine. The purpose was to evaluate the relationship between maximum velocity and sprint performance, and to compare acceleration patterns for fast and slow athletes. Using freely available online sources, data were collected for body mass and sprint performance (36.6m time with split intervals at 9.1 and 18.3m). For each athlete, split times were utilized to generate modeled curves of distance vs. time, velocity vs. time, and velocity vs. distance using a mono-exponential equation. Model parameters were used to quantify acceleration patterns as the ratio of maximum velocity to maximum acceleration (vmax / amax, or τ). Linear regression was used to evaluate the relationship between maximum velocity and sprint performance for the entire sample. Additionally, athletes were categorized into fast and slow groups based on maximum velocity, with independent t-tests and effect size statistics used to evaluate between-group differences in sprint performance and acceleration patterns. Results indicated that maximum velocity was strongly correlated with sprint performance across 9.1m, 18.3m, and 36.6m (r of 0.72, 0.83, and 0.94, respectively). However, both fast and slow groups accelerated in a similar pattern relative to maximum velocity (τ = 0.768 ± 0.068s for the fast group and τ = 0.773 ± 0.070s for the slow group). We conclude that maximum velocity is of critical importance to 36.6m time, and inclusion of more maximum velocity training may be warranted for athletes preparing for the NFL Combine.
Pattern formation, logistics, and maximum path probability
Kirkaldy, J. S.
1985-05-01
The concept of pattern formation, which to current researchers is a synonym for self-organization, carries the connotation of deductive logic together with the process of spontaneous inference. Defining a pattern as an equivalence relation on a set of thermodynamic objects, we establish that a large class of irreversible pattern-forming systems, evolving along idealized quasisteady paths, approaches the stable steady state as a mapping upon the formal deductive imperatives of a propositional function calculus. In the preamble the classical reversible thermodynamics of composite systems is analyzed as an externally manipulated system of space partitioning and classification based on ideal enclosures and diaphragms. The diaphragms have discrete classification capabilities which are designated in relation to conserved quantities by descriptors such as impervious, diathermal, and adiabatic. Differentiability in the continuum thermodynamic calculus is invoked as equivalent to analyticity and consistency in the underlying class or sentential calculus. The seat of inference, however, rests with the thermodynamicist. In the transition to an irreversible pattern-forming system the defined nature of the composite reservoirs remains, but a given diaphragm is replaced by a pattern-forming system which by its nature is a spontaneously evolving volume partitioner and classifier of invariants. The seat of volition or inference for the classification system is thus transferred from the experimenter or theoretician to the diaphragm, and with it the full deductive facility. The equivalence relations or partitions associated with the emerging patterns may thus be associated with theorems of the natural pattern-forming calculus. The entropy function, together with its derivatives, is the vehicle which relates the logistics of reservoirs and diaphragms to the analog logistics of the continuum. Maximum path probability or second-order differentiability of the entropy in isolation are
OPTIMIZING THE SHAPE OF ROTOR BLADES FOR MAXIMUM POWER EXTRACTION IN MARINE CURRENT TURBINES
J.A. Esfahani
2012-12-01
Full Text Available In this paper the shape of rotor blades in Marine Current Turbines (MCTs are investigated. The evaluation of hydrodynamic loads on blades is performed based on the Blade Element Momentum (BEM theory. The shape of blades is optimized according to the main parameters in the configuration and operation of these devices. The optimization is conducted based on the ability of the blades to harness the maximum energy during operating. The main parameters investigated are the tip speed ratio and angle of attack. Furthermore, the influence of these parameters on the maximum energy extraction from fluid flow over a hydrofoil is evaluated. It is shown that the effect of the angle of attack on power extraction is greater than that of the tip speed ratio, while both are found to be significant. Additionally, the proper angle of attack is the angle at which the lift to drag ratio is at its maximum value. However, if a proper angle of attack is chosen, the variations in power coefficient would not be effectively changed with small variations in the tip speed ratio.
Relative azimuth inversion by way of damped maximum correlation estimates
Ringler, A.T.; Edwards, J.D.; Hutt, C.R.; Shelly, F.
2012-01-01
Horizontal seismic data are utilized in a large number of Earth studies. Such work depends on the published orientations of the sensitive axes of seismic sensors relative to true North. These orientations can be estimated using a number of different techniques: SensOrLoc (Sensitivity, Orientation and Location), comparison to synthetics (Ekstrom and Busby, 2008), or by way of magnetic compass. Current methods for finding relative station azimuths are unable to do so with arbitrary precision quickly because of limitations in the algorithms (e.g. grid search methods). Furthermore, in order to determine instrument orientations during station visits, it is critical that any analysis software be easily run on a large number of different computer platforms and the results be obtained quickly while on site. We developed a new technique for estimating relative sensor azimuths by inverting for the orientation with the maximum correlation to a reference instrument, using a non-linear parameter estimation routine. By making use of overlapping windows, we are able to make multiple azimuth estimates, which helps to identify the confidence of our azimuth estimate, even when the signal-to-noise ratio (SNR) is low. Finally, our algorithm has been written as a stand-alone, platform independent, Java software package with a graphical user interface for reading and selecting data segments to be analyzed.
Electronic Structure and Maximum Energy Product of MnBi
Jihoon Park
2014-08-01
Full Text Available We have performed first-principles calculations to obtain magnetic moment, magnetocrystalline anisotropy energy (MAE, i.e., the magnetic crystalline anisotropy constant (K, and the Curie temperature (Tc of low temperature phase (LTP MnBi and also estimated the maximum energy product (BHmax at elevated temperatures. The full-potential linearized augmented plane wave (FPLAPW method, based on density functional theory (DFT within the local spin density approximation (LSDA, was used to calculate the electronic structure of LPM MnBi. The Tc was calculated by the mean field theory. The calculated magnetic moment, MAE, and Tc are 3.63 μB/f.u. (formula unit (79 emu/g or 714 emu/cm3, −0.163 meV/u.c. (or K = −0.275 × 106 J/m3 and 711 K, respectively. The (BHmax at the elevated temperatures was estimated by combining experimental coercivity (Hci and the temperature dependence of magnetization (Ms(T. The (BHmax is 17.7 MGOe at 300 K, which is in good agreement with the experimental result for directionally-solidified LTP MnBi (17 MGOe. In addition, a study of electron density maps and the lattice constant c/a ratio dependence of the magnetic moment suggested that doping of a third element into interstitial sites of LTP MnBi can increase the Ms.
Maximum SINR Synchronization Strategies in Multiuser Filter Bank Schemes
Pecile Francesco
2010-01-01
Full Text Available We consider synchronization in a multiuser filter bank uplink system with single-user detection. Perfect user synchronization is not the optimal choice as the intuition would suggest. To maximize performance the synchronization parameters have to be chosen to maximize the signal-to-interference-plus-noise ratio (SINR at each equalizer subchannel output. However, the resulting filter bank receiver structure becomes complex. Therefore, we consider two simplified synchronization metrics that are based on the maximization of the average SINR of a given user or the aggregate SINR of all users. Furthermore, a relaxation of the aggregate SINR metric allows implementing an efficient multiuser analysis filter bank. This receiver deploys two fractionally spaced analysis stages. Each analysis stage is efficiently implemented via a polyphase filter bank, followed by an extended discrete Fourier transform that allows the user frequency offsets to be partly compensated. Then, sub-channel maximum SINR equalization is used. We discuss the application of the proposed solution to Orthogonal Frequency Division Multiple Access (OFDMA and multiuser Filtered Multitone (FMT systems.
tmle : An R Package for Targeted Maximum Likelihood Estimation
Susan Gruber
2012-11-01
Full Text Available Targeted maximum likelihood estimation (TMLE is a general approach for constructing an efficient double-robust semi-parametric substitution estimator of a causal effect parameter or statistical association measure. tmle is a recently developed R package that implements TMLE of the effect of a binary treatment at a single point in time on an outcome of interest, controlling for user supplied covariates, including an additive treatment effect, relative risk, odds ratio, and the controlled direct effect of a binary treatment controlling for a binary intermediate variable on the pathway from treatment to the out- come. Estimation of the parameters of a marginal structural model is also available. The package allows outcome data with missingness, and experimental units that contribute repeated records of the point-treatment data structure, thereby allowing the analysis of longitudinal data structures. Relevant factors of the likelihood may be modeled or fit data-adaptively according to user specifications, or passed in from an external estimation procedure. Effect estimates, variances, p values, and 95% confidence intervals are provided by the software.
Rayleigh-maximum-likelihood bilateral filter for ultrasound image enhancement.
Li, Haiyan; Wu, Jun; Miao, Aimin; Yu, Pengfei; Chen, Jianhua; Zhang, Yufeng
2017-04-17
Ultrasound imaging plays an important role in computer diagnosis since it is non-invasive and cost-effective. However, ultrasound images are inevitably contaminated by noise and speckle during acquisition. Noise and speckle directly impact the physician to interpret the images and decrease the accuracy in clinical diagnosis. Denoising method is an important component to enhance the quality of ultrasound images; however, several limitations discourage the results because current denoising methods can remove noise while ignoring the statistical characteristics of speckle and thus undermining the effectiveness of despeckling, or vice versa. In addition, most existing algorithms do not identify noise, speckle or edge before removing noise or speckle, and thus they reduce noise and speckle while blurring edge details. Therefore, it is a challenging issue for the traditional methods to effectively remove noise and speckle in ultrasound images while preserving edge details. To overcome the above-mentioned limitations, a novel method, called Rayleigh-maximum-likelihood switching bilateral filter (RSBF) is proposed to enhance ultrasound images by two steps: noise, speckle and edge detection followed by filtering. Firstly, a sorted quadrant median vector scheme is utilized to calculate the reference median in a filtering window in comparison with the central pixel to classify the target pixel as noise, speckle or noise-free. Subsequently, the noise is removed by a bilateral filter and the speckle is suppressed by a Rayleigh-maximum-likelihood filter while the noise-free pixels are kept unchanged. To quantitatively evaluate the performance of the proposed method, synthetic ultrasound images contaminated by speckle are simulated by using the speckle model that is subjected to Rayleigh distribution. Thereafter, the corrupted synthetic images are generated by the original image multiplied with the Rayleigh distributed speckle of various signal to noise ratio (SNR) levels and
Cardiorespiratory Fitness of Inmates of a Maximum Security Prison ...
USER
Maximum Security Prison; and also to determine the effects of age, gender, and period of incarceration on CRF. A total of 247 apparently healthy inmates of Maiduguri Maximum Security ... with different types of cardiovascular and metabolic.
Maximum likelihood polynomial regression for robust speech recognition
LU Yong; WU Zhenyang
2011-01-01
The linear hypothesis is the main disadvantage of maximum likelihood linear re- gression （MLLR）. This paper applies the polynomial regression method to model adaptation and establishes a nonlinear model adaptation algorithm using maximum likelihood polyno
CO2 maximum in the oxygen minimum zone (OMZ)
Paulmier, A.; Ruiz-Pino, D.; Garçon, V.
2011-02-01
Oxygen minimum zones (OMZs), known as suboxic layers which are mainly localized in the Eastern Boundary Upwelling Systems, have been expanding since the 20th "high CO2" century, probably due to global warming. OMZs are also known to significantly contribute to the oceanic production of N2O, a greenhouse gas (GHG) more efficient than CO2. However, the contribution of the OMZs on the oceanic sources and sinks budget of CO2, the main GHG, still remains to be established. We present here the dissolved inorganic carbon (DIC) structure, associated locally with the Chilean OMZ and globally with the main most intense OMZs (O22225 μmol kg-1, up to 2350 μmol kg-1) have been reported over the whole OMZ thickness, allowing the definition for all studied OMZs a Carbon Maximum Zone (CMZ). Locally off Chile, the shallow cores of the OMZ and CMZ are spatially and temporally collocated at 21° S, 30° S and 36° S despite different cross-shore, long-shore and seasonal configurations. Globally, the mean state of the main OMZs also corresponds to the largest carbon reserves of the ocean in subsurface waters. The CMZs-OMZs could then induce a positive feedback for the atmosphere during upwelling activity, as potential direct local sources of CO2. The CMZ paradoxically presents a slight "carbon deficit" in its core (~10%), meaning a DIC increase from the oxygenated ocean to the OMZ lower than the corresponding O2 decrease (assuming classical C/O molar ratios). This "carbon deficit" would be related to regional thermal mechanisms affecting faster O2 than DIC (due to the carbonate buffer effect) and occurring upstream in warm waters (e.g., in the Equatorial Divergence), where the CMZ-OMZ core originates. The "carbon deficit" in the CMZ core would be mainly compensated locally at the oxycline, by a "carbon excess" induced by a specific remineralization. Indeed, a possible co-existence of bacterial heterotrophic and autotrophic processes usually occurring at different depths could
CO2 maximum in the oxygen minimum zone (OMZ
V. Garçon
2011-02-01
Full Text Available Oxygen minimum zones (OMZs, known as suboxic layers which are mainly localized in the Eastern Boundary Upwelling Systems, have been expanding since the 20th "high CO2" century, probably due to global warming. OMZs are also known to significantly contribute to the oceanic production of N2O, a greenhouse gas (GHG more efficient than CO2. However, the contribution of the OMZs on the oceanic sources and sinks budget of CO2, the main GHG, still remains to be established. We present here the dissolved inorganic carbon (DIC structure, associated locally with the Chilean OMZ and globally with the main most intense OMZs (O2−1 in the open ocean. To achieve this, we examine simultaneous DIC and O2 data collected off Chile during 4 cruises (2000–2002 and a monthly monitoring (2000–2001 in one of the shallowest OMZs, along with international DIC and O2 databases and climatology for other OMZs. High DIC concentrations (>2225 μmol kg−1, up to 2350 μmol kg−1 have been reported over the whole OMZ thickness, allowing the definition for all studied OMZs a Carbon Maximum Zone (CMZ. Locally off Chile, the shallow cores of the OMZ and CMZ are spatially and temporally collocated at 21° S, 30° S and 36° S despite different cross-shore, long-shore and seasonal configurations. Globally, the mean state of the main OMZs also corresponds to the largest carbon reserves of the ocean in subsurface waters. The CMZs-OMZs could then induce a positive feedback for the atmosphere during upwelling activity, as potential direct local sources of CO2. The CMZ paradoxically presents a slight "carbon deficit" in its core (~10%, meaning a DIC increase from the oxygenated ocean to the OMZ lower than the corresponding O2 decrease (assuming classical C/O molar ratios. This "carbon deficit" would be related to regional thermal mechanisms affecting faster O2 than DIC (due to the carbonate buffer effect and occurring upstream in warm waters (e.g., in the Equatorial Divergence
M. Mihelich
2014-11-01
Full Text Available We derive rigorous results on the link between the principle of maximum entropy production and the principle of maximum Kolmogorov–Sinai entropy using a Markov model of the passive scalar diffusion called the Zero Range Process. We show analytically that both the entropy production and the Kolmogorov–Sinai entropy seen as functions of f admit a unique maximum denoted fmaxEP and fmaxKS. The behavior of these two maxima is explored as a function of the system disequilibrium and the system resolution N. The main result of this article is that fmaxEP and fmaxKS have the same Taylor expansion at first order in the deviation of equilibrium. We find that fmaxEP hardly depends on N whereas fmaxKS depends strongly on N. In particular, for a fixed difference of potential between the reservoirs, fmaxEP(N tends towards a non-zero value, while fmaxKS(N tends to 0 when N goes to infinity. For values of N typical of that adopted by Paltridge and climatologists (N ≈ 10 ~ 100, we show that fmaxEP and fmaxKS coincide even far from equilibrium. Finally, we show that one can find an optimal resolution N* such that fmaxEP and fmaxKS coincide, at least up to a second order parameter proportional to the non-equilibrium fluxes imposed to the boundaries. We find that the optimal resolution N* depends on the non equilibrium fluxes, so that deeper convection should be represented on finer grids. This result points to the inadequacy of using a single grid for representing convection in climate and weather models. Moreover, the application of this principle to passive scalar transport parametrization is therefore expected to provide both the value of the optimal flux, and of the optimal number of degrees of freedom (resolution to describe the system.
Image quality and high contrast improvements on VLT/NACO
Girard, Julien H V; Mawet, Dimitri; Kasper, Markus; Zins, Gérard; Neichel, Benoît; Kolb, Johann; Christiaens, Valentin; Tourneboeuf, Martin; 10.1117/12.925660
2012-01-01
NACO is the famous and versatile diffraction limited NIR imager and spectrograph with which ESO celebrated 10 years of Adaptive Optics at the VLT. Since two years a substantial effort has been put in to understanding and fixing issues that directly affect the image quality and the high contrast performances of the instrument. Experiments to compensate the non-common-path aberrations and recover the highest possible Strehl ratios have been carried out successfully and a plan is hereafter described to perform such measurements regularly. The drift associated to pupil tracking since 2007 was fixed in October 2011. NACO is therefore even better suited for high contrast imaging and can be used with coronagraphic masks in the image plane. Some contrast measurements are shown and discussed. The work accomplished on NACO will serve as reference for the next generation instruments on the VLT, especially those working at the diffraction limit and making use of angular differential imaging (i.e. SPHERE, VISIR, possibly ...
20 CFR 617.14 - Maximum amount of TRA.
2010-04-01
... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Maximum amount of TRA. 617.14 Section 617.14... FOR WORKERS UNDER THE TRADE ACT OF 1974 Trade Readjustment Allowances (TRA) § 617.14 Maximum amount of TRA. (a) General rule. Except as provided under paragraph (b) of this section, the maximum amount of...
40 CFR 94.107 - Determination of maximum test speed.
2010-07-01
... specified in 40 CFR 1065.510. These data points form the lug curve. It is not necessary to generate the... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Determination of maximum test speed... Determination of maximum test speed. (a) Overview. This section specifies how to determine maximum test...
14 CFR 25.1505 - Maximum operating limit speed.
2010-01-01
... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Maximum operating limit speed. 25.1505... Operating Limitations § 25.1505 Maximum operating limit speed. The maximum operating limit speed (V MO/M MO airspeed or Mach Number, whichever is critical at a particular altitude) is a speed that may not...
Maximum Performance Tests in Children with Developmental Spastic Dysarthria.
Wit, J.; And Others
1993-01-01
Three Maximum Performance Tasks (Maximum Sound Prolongation, Fundamental Frequency Range, and Maximum Repetition Rate) were administered to 11 children (ages 6-11) with spastic dysarthria resulting from cerebral palsy and 11 controls. Despite intrasubject and intersubject variability in normal and pathological speakers, the tasks were found to be…
Maximum physical capacity testing in cancer patients undergoing chemotherapy
Knutsen, L.; Quist, M; Midtgaard, J
2006-01-01
BACKGROUND: Over the past few years there has been a growing interest in the field of physical exercise in rehabilitation of cancer patients, leading to requirements for objective maximum physical capacity measurement (maximum oxygen uptake (VO(2max)) and one-repetition maximum (1RM)) to determine...
Maximum detection range limitation of pulse laser radar with Geiger-mode avalanche photodiode array
Luo, Hanjun; Xu, Benlian; Xu, Huigang; Chen, Jingbo; Fu, Yadan
2015-05-01
When designing and evaluating the performance of laser radar system, maximum detection range achievable is an essential parameter. The purpose of this paper is to propose a theoretical model of maximum detection range for simulating the Geiger-mode laser radar's ranging performance. Based on the laser radar equation and the requirement of the minimum acceptable detection probability, and assuming the primary electrons triggered by the echo photons obey Poisson statistics, the maximum range theoretical model is established. By using the system design parameters, the influence of five main factors, namely emitted pulse energy, noise, echo position, atmospheric attenuation coefficient, and target reflectivity on the maximum detection range are investigated. The results show that stronger emitted pulse energy, lower noise level, more front echo position in the range gate, higher atmospheric attenuation coefficient, and higher target reflectivity can result in greater maximum detection range. It is also shown that it's important to select the minimum acceptable detection probability, which is equivalent to the system signal-to-noise ratio for producing greater maximum detection range and lower false-alarm probability.
Carbon Monoxide Mixing Ratio System
Oak Ridge National Laboratory — The Southern Great Plains (SGP) Carbon Monoxide (CO) system provides high-precision atmospheric concentration measurements of CO mixing ratio (ppbv dry air) every 10...
Pressure Ratio to Thermal Environments
Lopez, Pedro; Wang, Winston
2012-01-01
A pressure ratio to thermal environments (PRatTlE.pl) program is a Perl language code that estimates heating at requested body point locations by scaling the heating at a reference location times a pressure ratio factor. The pressure ratio factor is the ratio of the local pressure at the reference point and the requested point from CFD (computational fluid dynamics) solutions. This innovation provides pressure ratio-based thermal environments in an automated and traceable method. Previously, the pressure ratio methodology was implemented via a Microsoft Excel spreadsheet and macro scripts. PRatTlE is able to calculate heating environments for 150 body points in less than two minutes. PRatTlE is coded in Perl programming language, is command-line-driven, and has been successfully executed on both the HP and Linux platforms. It supports multiple concurrent runs. PRatTlE contains error trapping and input file format verification, which allows clear visibility into the input data structure and intermediate calculations.
Integral equations with contrasting kernels
Theodore Burton
2008-01-01
Full Text Available In this paper we study integral equations of the form $x(t=a(t-\\int^t_0 C(t,sx(sds$ with sharply contrasting kernels typified by $C^*(t,s=\\ln (e+(t-s$ and $D^*(t,s=[1+(t-s]^{-1}$. The kernel assigns a weight to $x(s$ and these kernels have exactly opposite effects of weighting. Each type is well represented in the literature. Our first project is to show that for $a\\in L^2[0,\\infty$, then solutions are largely indistinguishable regardless of which kernel is used. This is a surprise and it leads us to study the essential differences. In fact, those differences become large as the magnitude of $a(t$ increases. The form of the kernel alone projects necessary conditions concerning the magnitude of $a(t$ which could result in bounded solutions. Thus, the next project is to determine how close we can come to proving that the necessary conditions are also sufficient. The third project is to show that solutions will be bounded for given conditions on $C$ regardless of whether $a$ is chosen large or small; this is important in real-world problems since we would like to have $a(t$ as the sum of a bounded, but badly behaved function, and a large well behaved function.
Comparison Between Bayesian and Maximum Entropy Analyses of Flow Networks†
Steven H. Waldrip
2017-02-01
Full Text Available We compare the application of Bayesian inference and the maximum entropy (MaxEnt method for the analysis of ﬂow networks, such as water, electrical and transport networks. The two methods have the advantage of allowing a probabilistic prediction of ﬂow rates and other variables, when there is insufﬁcient information to obtain a deterministic solution, and also allow the effects of uncertainty to be included. Both methods of inference update a prior to a posterior probability density function (pdf by the inclusion of new information, in the form of data or constraints. The MaxEnt method maximises an entropy function subject to constraints, using the method of Lagrange multipliers,to give the posterior, while the Bayesian method ﬁnds its posterior by multiplying the prior with likelihood functions incorporating the measured data. In this study, we examine MaxEnt using soft constraints, either included in the prior or as probabilistic constraints, in addition to standard moment constraints. We show that when the prior is Gaussian,both Bayesian inference and the MaxEnt method with soft prior constraints give the same posterior means, but their covariances are different. In the Bayesian method, the interactions between variables are applied through the likelihood function, using second or higher-order cross-terms within the posterior pdf. In contrast, the MaxEnt method incorporates interactions between variables using Lagrange multipliers, avoiding second-order correlation terms in the posterior covariance. The MaxEnt method with soft prior constraints, therefore, has a numerical advantage over Bayesian inference, in that the covariance terms are avoided in its integrations. The second MaxEnt method with soft probabilistic constraints is shown to give posterior means of similar, but not identical, structure to the other two methods, due to its different formulation.
Impact of soil moisture on extreme maximum temperatures in Europe
Kirien Whan
2015-09-01
Full Text Available Land-atmosphere interactions play an important role for hot temperature extremes in Europe. Dry soils may amplify such extremes through feedbacks with evapotranspiration. While previous observational studies generally focused on the relationship between precipitation deficits and the number of hot days, we investigate here the influence of soil moisture (SM on summer monthly maximum temperatures (TXx using water balance model-based SM estimates (driven with observations and temperature observations. Generalized extreme value distributions are fitted to TXx using SM as a covariate. We identify a negative relationship between SM and TXx, whereby a 100 mm decrease in model-based SM is associated with a 1.6 °C increase in TXx in Southern-Central and Southeastern Europe. Dry SM conditions result in a 2–4 °C increase in the 20-year return value of TXx compared to wet conditions in these two regions. In contrast with SM impacts on the number of hot days (NHD, where low and high surface-moisture conditions lead to different variability, we find a mostly linear dependency of the 20-year return value on surface-moisture conditions. We attribute this difference to the non-linear relationship between TXx and NHD that stems from the threshold-based calculation of NHD. Furthermore the employed SM data and the Standardized Precipitation Index (SPI are only weakly correlated in the investigated regions, highlighting the importance of evapotranspiration and runoff for resulting SM. Finally, in a case study for the hot 2003 summer we illustrate that if 2003 spring conditions in Southern-Central Europe had been as dry as in the more recent 2011 event, temperature extremes in summer would have been higher by about 1 °C, further enhancing the already extreme conditions which prevailed in that year.
Berry, Vincent; Nicolas, François
2006-01-01
Given a set of evolutionary trees on a same set of taxa, the maximum agreement subtree problem (MAST), respectively, maximum compatible tree problem (MCT), consists of finding a largest subset of taxa such that all input trees restricted to these taxa are isomorphic, respectively compatible. These problems have several applications in phylogenetics such as the computation of a consensus of phylogenies obtained from different data sets, the identification of species subjected to horizontal gene transfers and, more recently, the inference of supertrees, e.g., Trees Of Life. We provide two linear time algorithms to check the isomorphism, respectively, compatibility, of a set of trees or otherwise identify a conflict between the trees with respect to the relative location of a small subset of taxa. Then, we use these algorithms as subroutines to solve MAST and MCT on rooted or unrooted trees of unbounded degree. More precisely, we give exact fixed-parameter tractable algorithms, whose running time is uniformly polynomial when the number of taxa on which the trees disagree is bounded. The improves on a known result for MAST and proves fixed-parameter tractability for MCT.
无
2010-01-01
The pressure ratio required for a turbocharger centrifugal compressor increases with internal combustion engine power density. High pressure ratio causes a transonic flow field at the impeller inducer. Transonic flow narrows the stable flow range and de-teriorates stage efficiency. In this work, an advanced high pressure ratio transonic compressor was designed. The experimental results show that the maximum pressure ratio of this turbocharger is about 4.2, the maximum efficiency is above 80% and the stable flow range at the designed rotating speed is up to 34%. A turbocharger with this transonic compressor has been applied to some vehicle research actually, and improved power density by 40%.
Uniform Silicon Isotope Ratios Across the Milky Way Galaxy
Monson, Nathaniel N.; Morris, Mark R.; Young, Edward D.
2017-04-01
We report the relative abundances of the three stable isotopes of silicon, 28Si, 29Si, and 30Si, across the Galaxy using the v=0,J=1\\to 0 transition of silicon monoxide. The chosen sources represent a range in Galactocentric radii ({R}{GC}) from 0 to 9.8 kpc. The high spectral resolution and sensitivity afforded by the Green Bank Telescope permit isotope ratios to be corrected for optical depths. The optical-depth-corrected data indicate that the secondary-to-primary silicon isotope ratios {}29{Si}{/}28{Si} and {}30{Si}{/}28{Si} vary much less than predicted on the basis of other stable isotope ratio gradients across the Galaxy. Indeed, there is no detectable variation in Si isotope ratios with {R}{GC}. This lack of an isotope ratio gradient stands in stark contrast to the monotonically decreasing trend with {R}{GC} exhibited by published secondary-to-primary oxygen isotope ratios. These results, when considered in the context of the expectations for chemical evolution, suggest that the reported oxygen isotope ratio trends, and perhaps those for carbon as well, require further investigation. The methods developed in this study for SiO isotopologue ratio measurements are equally applicable to Galactic oxygen, carbon, and nitrogen isotope ratio measurements, and should prove useful for future observations of these isotope systems.
Foley, Daniel; Browne, Jacinta E; Zhuang, Xiahai; Sheane, Barry; O'Driscoll, Dearbhail; Cannon, Daniel; Sheehy, Niall; Meaney, James F; Fagan, Andrew J
2014-12-01
An investigation was carried out into the effect of three image registration techniques on the diagnostic image quality of contrast-enhanced magnetic resonance angiography (CE-MRA) images. Whole-body CE-MRA data from the lower legs of 27 patients recruited onto a study of asymptomatic atherosclerosis were processed using three deformable image registration algorithms. The resultant diagnostic image quality was evaluated qualitatively in a clinical evaluation by four expert observers, and quantitatively by measuring contrast-to-noise ratios and volumes of blood vessels, and assessing the techniques' ability to correct for varying degrees of motion. The first registration algorithm ('AIR') introduced significant stenosis-mimicking artefacts into the blood vessels' appearance, observed both qualitatively (clinical evaluation) and quantitatively (vessel volume measurements). The two other algorithms ('Slicer' and 'SEMI'), based on the normalised mutual information (NMI) concept and designed specifically to deal with variations in signal intensity as found in contrast-enhanced image data, did not suffer from this serious issue but were rather found to significantly improve the diagnostic image quality both qualitatively and quantitatively, and demonstrated a significantly improved ability to deal with the common problem of patient motion. This work highlights both the significant benefits to be gained through the use of suitable registration algorithms and the deleterious effects of an inappropriate choice of algorithm for contrast-enhanced MRI data. The maximum benefit was found in the lower legs, where the small arterial vessel diameters and propensity for leg movement during image acquisitions posed considerable problems in making accurate diagnoses from the un-registered images. Copyright © 2014 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.
Appelbaum, J.; Singer, S.
1989-01-01
A calculation of the starting torque ratio of permanent magnet, series, and shunt-excited dc motors powered by solar cell arrays is presented for two cases, i.e., with and without a maximum-power-point tracker (MPPT). Defining motor torque magnification by the ratio of the motor torque with an MPPT to the motor torque without an MPPT, a magnification of 3 for the permanent magnet motor and a magnification of 7 for both the series and shunt motors are obtained. The study also shows that all motor types are less sensitive to solar insolation variation in systems including MPPTs as compared to systems without MPPTs.
[The simultaneous contrast of the colors in Van Gogh paints].
Cernea, P
2002-01-01
Vincent Van Gogh, Dutchman painter, is a forerunner but also a spokesman of the expressionism. His life was short and sad, marked by a psychic instability. In his paintings the color is subordinated of some subjective motivations. Van Gogh uses complementary colors to get a maximum intensity of the overlapped tones. The chromatic increase serves to obtain some strong emotions. In his landscapes the special distances are suggested through tonal distances. The increase of the pure tones through complementary contrast, the cancel of the imitation colors through sensation-colors, the explosive chromatic are characteristic of her painting. In his singular creation, Vincent Van Gogh created his suffering ego.
Carbon nanoparticles as a multimodal thermoacoustic and photoacoustic contrast agent
Cai, Xin; Wu, Lina; Xing, Wenxin; Xia, Jun; Nie, Liming; Zhang, Ruiying; Lanza, Gregory M.; Shen, Baozhong; Pan, Dipanjan; Wang, Lihong V.
2013-03-01
We demonstrated the potential of carbon nanoparticles (CNPs) as exogenous contrast agents for both thermoacoustic (TA) tomography (TAT) and photoacoustic (PA) tomography (PAT). In comparison to deionized water, the CNPs provided a four times stronger signal in TAT at 3 GHz. In comparison to blood, The CNPs provided a much stronger signal in PAT over a broad wavelength range of 450-850 nm. Specifically, the maximum signal enhancement in PAT was 9.4 times stronger in the near-infrared window of 635-670 nm. In vivo blood-vessel PA imaging was performed non-invasively on a mouse femoral area. The images, captured after the tail vein injection of CNPs, show a gradual enhancement of the optical absorption in the vessels by up to 230%. The results indicate that CNPs can be potentially used as contrast agents for TAT and PAT to monitor the intravascular or extravascular pathways in clinical applications.
Leaf Dynamics of Panicum maximum under Future Climatic Changes.
Carlos Henrique Britto de Assis Prado
Full Text Available Panicum maximum Jacq. 'Mombaça' (C4 was grown in field conditions with sufficient water and nutrients to examine the effects of warming and elevated CO2 concentrations during the winter. Plants were exposed to either the ambient temperature and regular atmospheric CO2 (Control; elevated CO2 (600 ppm, eC; canopy warming (+2°C above regular canopy temperature, eT; or elevated CO2 and canopy warming (eC+eT. The temperatures and CO2 in the field were controlled by temperature free-air controlled enhancement (T-FACE and mini free-air CO2 enrichment (miniFACE facilities. The most green, expanding, and expanded leaves and the highest leaf appearance rate (LAR, leaves day(-1 and leaf elongation rate (LER, cm day(-1 were observed under eT. Leaf area and leaf biomass were higher in the eT and eC+eT treatments. The higher LER and LAR without significant differences in the number of senescent leaves could explain why tillers had higher foliage area and leaf biomass in the eT treatment. The eC treatment had the lowest LER and the fewest expanded and green leaves, similar to Control. The inhibitory effect of eC on foliage development in winter was indicated by the fewer green, expanded, and expanding leaves under eC+eT than eT. The stimulatory and inhibitory effects of the eT and eC treatments, respectively, on foliage raised and lowered, respectively, the foliar nitrogen concentration. The inhibition of foliage by eC was confirmed by the eC treatment having the lowest leaf/stem biomass ratio and by the change in leaf biomass-area relationships from linear or exponential growth to rectangular hyperbolic growth under eC. Besides, eC+eT had a synergist effect, speeding up leaf maturation. Therefore, with sufficient water and nutrients in winter, the inhibitory effect of elevated CO2 on foliage could be partially offset by elevated temperatures and relatively high P. maximum foliage production could be achieved under future climatic change.
Leaf Dynamics of Panicum maximum under Future Climatic Changes.
Britto de Assis Prado, Carlos Henrique; Haik Guedes de Camargo-Bortolin, Lívia; Castro, Érique; Martinez, Carlos Alberto
2016-01-01
Panicum maximum Jacq. 'Mombaça' (C4) was grown in field conditions with sufficient water and nutrients to examine the effects of warming and elevated CO2 concentrations during the winter. Plants were exposed to either the ambient temperature and regular atmospheric CO2 (Control); elevated CO2 (600 ppm, eC); canopy warming (+2°C above regular canopy temperature, eT); or elevated CO2 and canopy warming (eC+eT). The temperatures and CO2 in the field were controlled by temperature free-air controlled enhancement (T-FACE) and mini free-air CO2 enrichment (miniFACE) facilities. The most green, expanding, and expanded leaves and the highest leaf appearance rate (LAR, leaves day(-1)) and leaf elongation rate (LER, cm day(-1)) were observed under eT. Leaf area and leaf biomass were higher in the eT and eC+eT treatments. The higher LER and LAR without significant differences in the number of senescent leaves could explain why tillers had higher foliage area and leaf biomass in the eT treatment. The eC treatment had the lowest LER and the fewest expanded and green leaves, similar to Control. The inhibitory effect of eC on foliage development in winter was indicated by the fewer green, expanded, and expanding leaves under eC+eT than eT. The stimulatory and inhibitory effects of the eT and eC treatments, respectively, on foliage raised and lowered, respectively, the foliar nitrogen concentration. The inhibition of foliage by eC was confirmed by the eC treatment having the lowest leaf/stem biomass ratio and by the change in leaf biomass-area relationships from linear or exponential growth to rectangular hyperbolic growth under eC. Besides, eC+eT had a synergist effect, speeding up leaf maturation. Therefore, with sufficient water and nutrients in winter, the inhibitory effect of elevated CO2 on foliage could be partially offset by elevated temperatures and relatively high P. maximum foliage production could be achieved under future climatic change.
High-contrast self-imaging with ordered optical elements
Naqavi, Ali; Rossi, Markus
2016-01-01
Creating arbitrary light patterns finds applications in various domains including lithography, beam shaping, metrology, sensing and imaging. We study the formation of high-contrast light patterns that are obtained by transmission through an ordered optical element based on self-imaging.By applying the phase-space method, we explain phenomena such as the Talbot and the angular Talbot effects. We show that the image contrast is maximum when the source is either a plane wave or a point source, and it has a minimum for a source with finite spatial extent. We compare these regimes and address some of their fundamental differences. Specifically, we prove that increasing the source divergence reduces the contrast for the plane wave illumination but increases it for the point source. Also, we show that to achieve high contrast with a point source, tuning the source size and its distance to the element is crucial.We furthermore indicate and explore the possibility of realizing highly complex light patterns by using a ...
Subharmonic contrast intravascular ultrasound for vasa vasorum imaging.
Goertz, David E; Frijlink, Martijn E; Tempel, Dennie; Bhagwandas, Vijay; Gisolf, Andries; Krams, Robert; de Jong, Nico; van der Steen, Antonius F W
2007-12-01
The feasibility of subharmonic contrast intravascular ultrasound (IVUS) imaging was investigated using a prototype nonlinear IVUS system and the commercial contrast agent Definity . The system employed a mechanically scanned commercial catheter with a custom transducer element fabricated to have sensitivity at both 15 and 30 MHz. Experiments were conducted at a fundamental frequency of 30 MHz (F30; 25% bandwidth), with on-axis pressures ranging from 0.12 to 0.79 MPa, as measured with a needle hydrophone. In vitro characterization experiments demonstrated the detection of 15 MHz subharmonic signals (SH15) when pressure levels reached 360 kPa. The formation of SH15 images was shown, with tissue signals suppressed to near the noise floor and contrast to tissue ratios were improved by up to 30 dB relative to F30. In vivo experiments were performed using the atherosclerotic rabbit aorta model. Following the bolus injection of contrast agent upstream of the imaging catheter, agent was detected within the aorta, vena cava and within the perivascular space. These results provide a first in vivo demonstration of subharmonic contrast IVUS and suggest its potential as a new technique for imaging vasa vasorum.
Using Contrastive Rhetoric in the ESL Classroom
Quinn, Janet M.
2012-01-01
Contrastive rhetoric studies the writing of second language learners to understand how it is affected by their first language and culture. The field of contrastive rhetoric is as multidimensional as second language writing is complex. It draws on the work of contrastive analysis, anthropology, linguistics, pedagogy, culture studies, translation…
Spatial contrast sensitivity in clinical neurology.
Bulens, C; Meerwaldt, J D; van der Wildt, G J; Keemink, C J
1988-01-01
We studied contrast sensitivity function in normal subjects and in three illustrative cases with various neurological disorders. This was done by measuring contrast sensitivity over a range of spatial frequencies for vertical sinewave grating stimuli. It is demonstrated that contrast sensitivity function can give information about visual function not obtainable by conventional test procedures.
Present and Last Glacial Maximum climates as states of maximum entropy production
Herbert, Corentin; Kageyama, Masa; Dubrulle, Berengere
2011-01-01
The Earth, like other planets with a relatively thick atmosphere, is not locally in radiative equilibrium and the transport of energy by the geophysical fluids (atmosphere and ocean) plays a fundamental role in determining its climate. Using simple energy-balance models, it was suggested a few decades ago that the meridional energy fluxes might follow a thermodynamic Maximum Entropy Production (MEP) principle. In the present study, we assess the MEP hypothesis in the framework of a minimal climate model based solely on a robust radiative scheme and the MEP principle, with no extra assumptions. Specifically, we show that by choosing an adequate radiative exchange formulation, the Net Exchange Formulation, a rigorous derivation of all the physical parameters can be performed. The MEP principle is also extended to surface energy fluxes, in addition to meridional energy fluxes. The climate model presented here is extremely fast, needs very little empirical data and does not rely on ad hoc parameterizations. We in...
Abhijit Sinha
2014-01-01
Full Text Available A comparative analysis on thermodynamic efficiency based on maximum power & power density conditions have been performed for a solar-driven Carnot heat engine with internal irreversibility. In this analysis, the heat transfer from the hot reservoir is to be in the radiation mode and the heat transfer to the cold reservoir is to be in the convection mode. The thermodynamic efficiency function, power & power density functions have been derived and maximization of the power functions have been performed for various design parameters. From the optimum conditions, the thermal efficiencies at maximum power and power densities have been obtained. The effects of internal irreversibility, extreme temperature ratios & specific engine size in area ratio between the hot & cold reservoirs as various design parameters on thermodynamic efficiencies have been investigated for both the conditions. The efficiencies have been compared with Curzon-Ahlborn & Carnot efficiencies respectively.The analysis showed that the efficiency at maximum power output is greater than the efficiency at maximum power density. And the efficiencies can be greater than the Curzon- Ahlborn`s efficiency only for low values of design parameters.
Determination of Optimum Compression Ratio: A Tribological Aspect
L. Yüksek
2013-12-01
Full Text Available Internal combustion engines are the primary energy conversion machines both in industry and transportation. Modern technologies are being implemented to engines to fulfill today's low fuel consumption demand. Friction energy consumed by the rubbing parts of the engines are becoming an important parameter for higher fuel efficiency. Rate of friction loss is primarily affected by sliding speed and the load acting upon rubbing surfaces. Compression ratio is the main parameter that increases the peak cylinder pressure and hence normal load on components. Aim of this study is to investigate the effect of compression ratio on total friction loss of a diesel engine. A variable compression ratio diesel engine was operated at four different compression ratios which were "12.96", "15:59", "18:03", "20:17". Brake power and speed was kept constant at predefined value while measuring the in- cylinder pressure. Friction mean effective pressure ( FMEP data were obtained from the in cylinder pressure curves for each compression ratio. Ratio of friction power to indicated power of the engine was increased from 22.83% to 37.06% with varying compression ratio from 12.96 to 20:17. Considering the thermal efficiency , FMEP and maximum in- cylinder pressure optimum compression ratio interval of the test engine was determined as 18.8 ÷ 19.6.
Internal polarization limits coronagraph contrast
Breckinridge, James Bernard; Lam, Wai Sze T.; Chipman, Russell A.
2015-08-01
The performance of exoplanet imaging coronagraphs is limited by internal polarization. The point spread function (PSF) of these systems is determined by the details of the opto-mechanical layout selected to package the system and by the highly reflective metal thin films needed to maintain high optical system transmittance. To obtain the high contrast levels needed for terrestrial exoplanet science requires a comprehensive understanding of the vector electromagnetic wave from the source through the system. The literature contains many studies of polarization transmissivity of telescopes and instruments for the purpose of photo-polarimetry. Here we report for the first time the effects of polarization on high-performance image quality.We modeled a typical 2.4-meter Cassegrain telescope system with one 90-degree fold mirror and analyzed the system for polarization aberrations.We find: 1. The image plane irradiance distribution is the linear superposition of four PSF images: One for each of the two orthogonal polarizations and one for each of two cross-product polarization terms. 2. The PSF image is brighter by 9% for one polarization component compared to its orthogonal state. 3. The image of the PSF for orthogonal components are shifted across the focal plane with respect to each other, causing the PSF image for astronomical sources (polarized or unpolarized) to become slightly elongated (elliptical) with a centroid separation of about 0.6 masec. 4. The orthogonally polarized components of unpolarized sources contain different wavefront aberrations, which are separated by approximately 32 milliwaves. This implies that a wavefront correction system cannot optimally correct the aberrations for all polarizations simultaneously. 5. The polarization aberrations couple small parts (~1E-5) of each polarization component of the light into the orthogonal polarization to create highly distorted secondary, or “ghost” PSF image.. The radius of the spatial extent of the 90
Incentive Ratios of Fisher Markets
Chen, Ning; Deng, Xuaitue; Zhang, Hongyang
2012-01-01
In a Fisher market, a market maker sells m items to n potential buyers. The buyers submit their utility functions and money endowments to the market maker, who, upon receiving submitted information, derives market equilibrium prices and allocations of its items. While agents may benefit...... by misreporting their private information, we show that the percentage of improvement by a unilateral strategic play, called incentive ratio, is rather limited—it is less than 2 for linear markets and at most $e^{1/e}\\thickapprox 1.445$ for Cobb-Douglas markets. We further prove that both ratios are tight....
Ratio Bias and Policy Preferences
Pedersen, Rasmus Tue
2016-01-01
Numbers permeate modern political communication. While current scholarship on framing effects has focused on the persuasive effects of words and arguments, this article shows that framing of numbers can also substantially affect policy preferences. Such effects are caused by ratio bias, which...... is a general tendency to focus on numerators and pay insufficient attention to denominators in ratios. Using a population-based survey experiment, I demonstrate how differently framed but logically equivalent representations of the exact same numerical value can have large effects on citizens’ preferences...
Sex investment ratios in eusocial Hymenoptera support inclusive fitness theory.
Bourke, A F G
2015-11-01
Inclusive fitness theory predicts that sex investment ratios in eusocial Hymenoptera are a function of the relatedness asymmetry (relative relatedness to females and males) of the individuals controlling sex allocation. In monogynous ants (with one queen per colony), assuming worker control, the theory therefore predicts female-biased sex investment ratios, as found in natural populations. Recently, E.O. Wilson and M.A. Nowak criticized this explanation and presented an alternative hypothesis. The Wilson-Nowak sex ratio hypothesis proposes that, in monogynous ants, there is selection for a 1 : 1 numerical sex ratio to avoid males remaining unmated, which, given queens exceed males in size, results in a female-biased sex investment ratio. The hypothesis also asserts that, contrary to inclusive fitness theory, queens not workers control sex allocation and queen-worker conflict over sex allocation is absent. Here, I argue that the Wilson-Nowak sex ratio hypothesis is flawed because it contradicts Fisher's sex ratio theory, which shows that selection on sex ratio does not maximize the number of mated offspring and that the sex ratio proposed by the hypothesis is not an equilibrium for the queen. In addition, the hypothesis is not supported by empirical evidence, as it fails to explain 'split' (bimodal) sex ratios or data showing queen and worker control and ongoing queen-worker conflict. By contrast, these phenomena match predictions of inclusive fitness theory. Hence, the Wilson-Nowak sex ratio hypothesis fails both as an alternative hypothesis for sex investment ratios in eusocial Hymenoptera and as a critique of inclusive fitness theory.
Comparison of Folate Receptor Targeted Optical Contrast Agents for Intraoperative Molecular Imaging
Elizabeth De Jesus
2015-01-01
Full Text Available Background. Intraoperative imaging can identify cancer cells in order to improve resection; thus fluorescent contrast agents have emerged. Our objective was to do a preclinical comparison of two fluorescent dyes, EC17 and OTL38, which both target folate receptor but have different fluorochromes. Materials. HeLa and KB cells lines were used for in vitro and in vivo comparisons of EC17 and OTL38 brightness, sensitivity, pharmacokinetics, and biodistribution. In vivo experiments were then performed in mice. Results. The peak excitation and emission wavelengths of EC17 and OTL38 were 470/520 nm and 774/794 nm, respectively. In vitro, OTL38 required increased incubation time compared to EC17 for maximum fluorescence; however, peak signal-to-background ratio (SBR was 1.4-fold higher compared to EC17 within 60 minutes (p<0.001. Additionally, the SBR for detecting smaller quantity of cells was improved with OTL38. In vivo, the mean improvement in SBR of tumors visualized using OTL38 compared to EC17 was 3.3 fold (range 1.48–5.43. Neither dye caused noticeable toxicity in animal studies. Conclusions. In preclinical testing, OTL38 appears to have superior sensitivity and brightness compared to EC17. This coincides with the accepted belief that near infrared (NIR dyes tend to have less autofluorescence and scattering issues than visible wavelength fluorochromes.
[Physiopathology of nephropathy studied with contrast media].
Morales Buenrostro, L E; Tellez Zenteno, J F; Torre Delgadillo, A
2000-01-01
For the technological advances in diagnostic and therapeutic procedures, the use of intravenous contrast media in the hospital is more and more frequent. It can produce acute renal failure secondary to its nephrotoxicity known as contrast media nephropathy. This review describes the pathophysiologic mechanisms of contrast media injury, including cytotoxicity caused by hyperosmoloarity of contrast media, the hemodynamic factors and the role of the renin-angiotensin system, prostaglandins, oxygen free radicals, endothelin-1, adenosine, nitric oxide and others. The understanding of this information is of vital importance for the development of prophylactic strategies for contrast media nephropathy.
Maximum work configurations of finite potential capacity reservoir chemical engines
无
2010-01-01
An isothermal endoreversible chemical engine operating between the finite potential capacity high-chemical-potential reservoir and the infinite potential capacity low-chemical-potential reservoir has been studied in this work.Optimal control theory was applied to determine the optimal cycle configurations corresponding to the maximum work output per cycle for the fixed total cycle time and a universal mass transfer law.Analyses of special examples showed that the optimal cycle configuration with the mass transfer law g∝△μ,where△μis the chemical potential difference,is an isothermal endoreversible chemical engine cycle,in which the chemical potential(or the concentration) of the key component in the working substance of low-chemical-potential side is a constant,while the chemical potentials(or the concentrations) of the key component in the finite potential capacity high-chemical-potential reservoir and the corresponding side working substance change nonlinearly with time,and the difference of the chemical potentials(or the ratio of the concentrations) of the key component between the high-chemical-potential reservoir and the working substance is a constant.While the optimal cycle configuration with the mass transfer law g∝△μc,where △μc is the concentration difference,is different from that with the mass transfer law g∝△μ significantly.When the high-chemical-potential reservoir is also an infinite potential capacity chemical potential reservoir,the optimal cycle configuration of the isothermal endoreversible chemical engine consists of two constant chemical potential branches and two instantaneous constant mass-flux branches,which is independent of the mass transfer law.The object studied in this paper is general,and the results can provide some guidelines for optimal design and operation of real chemical engines.
Contrast Enhanced US in the Abdomen
Chung, Yong Eun; Kim, Ki Whang [Dept. of Radiology, Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul (Korea, Republic of)
2012-08-15
Contrast enhanced ultrasound, which was introduced in 1996, has been widely used in Europe and Eastern Asia. Ultrasound contrast agent can be classified as first generation and second generation, depending on the gas within the microbubble. With the first generation contrast agent, the high MI technique was used, and only intermittent scanning was possible due to destruction of the microbubble during scanning. Use of the second generation contrast agent with the low MI technique makes continuous scanning possible. Contrast enhanced US can be used in detection and differentiation of focal liver lesions. It is also helpful for monitoring of radiofrequency ablation and for targeting of US guided biopsy. Currently, because morphologic criteria alone may not reflect the response of the tumor to treatment, new criteria are needed for treatment evaluation after administration of anti-angiogenic agents. Contrast enhanced US could provide quantitative markers for evaluation of the response to treatment via use of dynamic contrast enhanced US. Due to cost-effectiveness, contrast enhanced US is not yet widely used in Korea; however, considering recent issues regarding contrast agent related adverse reaction, such as contrast induced nephropathy and nephrogenic systemic fibrosis, and radiation exposure, contrast enhanced US might be more widely used in Korea, as an alternative imaging modality in the future.
A Note on k-Limited Maximum Base
Yang Ruishun; Yang Xiaowei
2006-01-01
The problem of k-limited maximum base was specified into two special problems of k-limited maximum base; that is, let subset D of the problem of k-limited maximum base be an independent set and a circuit of the matroid, respectively. It was proved that under this circumstance the collections of k-limited base satisfy base axioms. Then a new matroid was determined, and the problem of k-limited maximum base was transformed to the problem of maximum base of this new matroid. Aiming at the problem, two algorithms, which in essence are greedy algorithms based on former matroid, were presented for the two special problems of k-limited maximum base. They were proved to be reasonable and more efficient than the algorithm presented by Ma Zhongfan in view of the complexity of algorithm.
Ratio Bias and Policy Preferences
Pedersen, Rasmus Tue
2016-01-01
Numbers permeate modern political communication. While current scholarship on framing effects has focused on the persuasive effects of words and arguments, this article shows that framing of numbers can also substantially affect policy preferences. Such effects are caused by ratio bias, which is ...
Gender Ratios for Reading Difficulties
Hawke, Jesse L.; Olson, Richard K.; Willcut, Erik G.; Wadsworth, Sally J.; DeFries, John C.
2009-01-01
The prevalence of reading difficulties is typically higher in males than females in both referred and research-identified samples, and the ratio of males to females is greater in more affected samples. To explore possible gender differences in reading performance, we analysed data from 1133 twin pairs in which at least one member of each pair had…
Li Xuejun; Qiu Weiliang; Yuan Yincai; Li Ping
2006-01-01
The relation between the maximum contact stress ratio and deflection angle is derived from Hertz contact theory when the deflection of rotary kiln supporting wheel happens. According to the analysis of practical example, the maximum contact stress ratio within the deflection range of rotary kiln supporting wheel is listed. The contact stress will increase largely when rotary kiln supporting wheel deflects with little angle,which probably will result in accidents correlating to safety. This will provide theory conference for the design,the operating condition analysis and adjusting of the rotary kiln.
Wang, Kaicun; Zhou, Chunlüe
2016-04-01
Global analyses of surface mean air temperature (Tm) are key datasets for climate change studies and provide fundamental evidences for global warming. However, the causes of regional contrasts in the warming rate revealed by such datasets, i.e., enhanced warming rates over the northern high latitudes and the "warming hole" over the central U.S., are still under debate. Here we show these regional contrasts depends on the calculation methods of Tm. Existing global analyses calculated Tm from daily minimum and maximum temperatures (T2). We found that T2 has a significant standard deviation error of 0.23 °C/decade in depicting the regional warming rate from 2000 to 2013 but can be reduced by two-thirds using Tm calculated from observations at four specific times (T4), which samples diurnal cycle of land surface air temperature more often. From 1973 to 1997, compared with T4, T2 significantly underestimated the warming rate over the central U.S. and overestimated the warming rate over the northern high latitudes. The ratio of the warming rate over China to that over the U.S. reduces from 2.3 by T2 to 1.4 by T4. This study shows that the studies of regional warming can be substantially improved by T4 instead of T2.
Contrast adaptation contributes to contrast-invariance of orientation tuning of primate V1 cells.
Lionel G Nowak
Full Text Available BACKGROUND: Studies in rodents and carnivores have shown that orientation tuning width of single neurons does not change when stimulus contrast is modified. However, in these studies, stimuli were presented for a relatively long duration (e. g., 4 seconds, making it possible that contrast adaptation contributed to contrast-invariance of orientation tuning. Our first purpose was to determine, in marmoset area V1, whether orientation tuning is still contrast-invariant with the stimulation duration is comparable to that of a visual fixation. METHODOLOGY/PRINCIPAL FINDINGS: We performed extracellular recordings and examined orientation tuning of single-units using static sine-wave gratings that were flashed for 200 msec. Sixteen orientations and three contrast levels, representing low, medium and high values in the range of effective contrasts for each neuron, were randomly intermixed. Contrast adaptation being a slow phenomenon, cells did not have enough time to adapt to each contrast individually. With this stimulation protocol, we found that the tuning width obtained at intermediate contrast was reduced to 89% (median, and that at low contrast to 76%, of that obtained at high contrast. Therefore, when probed with briefly flashed stimuli, orientation tuning is not contrast-invariant in marmoset V1. Our second purpose was to determine whether contrast adaptation contributes to contrast-invariance of orientation tuning. Stationary gratings were presented, as previously, for 200 msec with randomly varying orientations, but the contrast was kept constant within stimulation blocks lasting >20 sec, allowing for adaptation to the single contrast in use. In these conditions, tuning widths obtained at low contrast were still significantly less than at high contrast (median 85%. However, tuning widths obtained with medium and high contrast stimuli no longer differed significantly. CONCLUSIONS/SIGNIFICANCE: Orientation tuning does not appear to be contrast
Evaluation of Maximum O2 Consumption: Using Ergo-Spirometry in Severe Heart Failure
Majid Malekmohammad
2012-09-01
Full Text Available Although sport-physiologists have repeatedly analyzed respiratory gases through exercise, it is relatively new in the cardiovascular field and is obviously more acceptable than standard exercise test, which gives only information about the existence or absence of cardiovascular diseases (CVDs. Through the new method of exercise test, parameters including aerobic and anaerobic are checked and monitored. 22 severe cases of heart failure, who were candidates of heart transplantation, referring to Massih Daneshvari Hospital in Tehran from Nov. 2007 to Nov. 2008 enrolled this study. The study was designed as a cross-sectional performance and evaluated only patients with ejection fraction less than 30%. O2 mean consumption was 6.27±4.9 ml/kg/min at rest and 9.48±3.38 at anaerobic threshold (AT exceeding 13 ml/kg/min in maximum which was significantly more than the expected levels. Respiratory exchange ratio (RER was over 1 for all patients. This study could not find any statistical correlations between VO2 max and participants' ergonomic factors such as age, height, weight, BMI, as well as EF. This study showed no significant correlation between VO2 max and maximum heart rate (HR max, although O2 maximum consumption was rationally correlated with expiratory ventilation. This means that the patients achieved maximum ventilation through exercise in this study, but failed to have their maximum heart rate being led probably by HF-induced brady-arrhythmia or deconditioning of skeletal muscles.
An Interval Maximum Entropy Method for Quadratic Programming Problem
RUI Wen-juan; CAO De-xin; SONG Xie-wu
2005-01-01
With the idea of maximum entropy function and penalty function methods, we transform the quadratic programming problem into an unconstrained differentiable optimization problem, discuss the interval extension of the maximum entropy function, provide the region deletion test rules and design an interval maximum entropy algorithm for quadratic programming problem. The convergence of the method is proved and numerical results are presented. Both theoretical and numerical results show that the method is reliable and efficient.
Contrast-enhanced ultrasonography parameters in neural network diagnosis of liver tumors
Costin Teodor Streba; Mihaela Ionescu; Dan Ionut Gheonea; Larisa Sandulescu; Tudorel Ciurea; Adrian Saftoiu; Cristin Constantin Vere
2012-01-01
AIM:To study the role of time-intensity curve (TIC) analysis parameters in a complex system of neural networks designed to classify liver tumors.METHODS:We prospectively included 112 patients with hepatocellular carcinoma (HCC) (n =41),hypervascular (n =20) and hypovascular (n =12) liver metastases,hepatic hemangiomas (n =16) or focal fatty changes (n =23) who underwent contrast-enhanced ultrasonography in the Research Center of Gastroenterology and Hepatology,Craiova,Romania.We recorded full length movies of all contrast uptake phases and post-processed them offline by selecting two areas of interest (one for the tumor and one for the healthy surrounding parenchyma) and consecutive TIC analysis.The difference in maximum intensities,the time to reaching them and the aspect of the late/portal phase,as quantified by the neural network and a ratio between median intensities of the central and peripheral areas were analyzed by a feed forward back propagation multi-layer neural network which was trained to classify data into five distinct classes,corresponding to each type of liver lesion.RESULTS:The neural network had 94.45％ training accuracy (95％ CI:89.31％-97.21％) and 87.12％ testing accuracy (95％ CI:86.83％-93.17％).The automatic classification process registered 93.2％ sensitivity,89.7％ specificity,94.42％ positive predictive value and 87.57％ negative predictive value.The artificial neural networks (ANN) incorrectly classified as hemangyomas three HCC cases and two hypervascular metastases,while in turn misclassifying four liver hemangyomas as HCC (one case) and hypervascular metastases (three cases).Comparatively,human interpretation of TICs showed 94.1％ sensitivity,90.7％ specificity,95.11％ positive predictive value and 88.89％ negative predictive value.The accuracy and specificity of the ANN diagnosis system was similar to that of human interpretation of the TICs (P =0.225 and P =0.451,respectively).Hepatocellular carcinoma cases showed
Hutchinson, Thomas H. [Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth PL1 3DH (United Kingdom)], E-mail: thom1@pml.ac.uk; Boegi, Christian [BASF SE, Product Safety, GUP/PA, Z470, 67056 Ludwigshafen (Germany); Winter, Matthew J. [AstraZeneca Safety, Health and Environment, Brixham Environmental Laboratory, Devon TQ5 8BA (United Kingdom); Owens, J. Willie [The Procter and Gamble Company, Central Product Safety, 11810 East Miami River Road, Cincinnati, OH 45252 (United States)
2009-02-19
There is increasing recognition of the need to identify specific sublethal effects of chemicals, such as reproductive toxicity, and specific modes of actions of the chemicals, such as interference with the endocrine system. To achieve these aims requires criteria which provide a basis to interpret study findings so as to separate these specific toxicities and modes of action from not only acute lethality per se but also from severe inanition and malaise that non-specifically compromise reproductive capacity and the response of endocrine endpoints. Mammalian toxicologists have recognized that very high dose levels are sometimes required to elicit both specific adverse effects and present the potential of non-specific 'systemic toxicity'. Mammalian toxicologists have developed the concept of a maximum tolerated dose (MTD) beyond which a specific toxicity or action cannot be attributed to a test substance due to the compromised state of the organism. Ecotoxicologists are now confronted by a similar challenge and must develop an analogous concept of a MTD and the respective criteria. As examples of this conundrum, we note recent developments in efforts to validate protocols for fish reproductive toxicity and endocrine screens (e.g. some chemicals originally selected as 'negatives' elicited decreases in fecundity or changes in endpoints intended to be biomarkers for endocrine modes of action). Unless analogous criteria can be developed, the potentially confounding effects of systemic toxicity may then undermine the reliable assessment of specific reproductive effects or biomarkers such as vitellogenin or spiggin. The same issue confronts other areas of aquatic toxicology (e.g., genotoxicity) and the use of aquatic animals for preclinical assessments of drugs (e.g., use of zebrafish for drug safety assessment). We propose that there are benefits to adopting the concept of an MTD for toxicology and pharmacology studies using fish and other aquatic
Integer Programming Model for Maximum Clique in Graph
YUAN Xi-bo; YANG You; ZENG Xin-hai
2005-01-01
The maximum clique or maximum independent set of graph is a classical problem in graph theory. Combined with Boolean algebra and integer programming, two integer programming models for maximum clique problem,which improve the old results were designed in this paper. Then, the programming model for maximum independent set is a corollary of the main results. These two models can be easily applied to computer algorithm and software, and suitable for graphs of any scale. Finally the models are presented as Lingo algorithms, verified and compared by several examples.
Counterexamples to convergence theorem of maximum-entropy clustering algorithm
于剑; 石洪波; 黄厚宽; 孙喜晨; 程乾生
2003-01-01
In this paper, we surveyed the development of maximum-entropy clustering algorithm, pointed out that the maximum-entropy clustering algorithm is not new in essence, and constructed two examples to show that the iterative sequence given by the maximum-entropy clustering algorithm may not converge to a local minimum of its objective function, but a saddle point. Based on these results, our paper shows that the convergence theorem of maximum-entropy clustering algorithm put forward by Kenneth Rose et al. does not hold in general cases.
DPOAE generation dependence on primary frequencies ratio
Botti, Teresa; Sisto, Renata; Moleti, Arturo; D'Amato, Luisa; Sanjust, Filippo
2015-12-01
. Amplitude/phase vs ratio and ratio-frequency maps have been analyzed both in numerical and laboratory data. As already observed in animal studies [4], the generation of 2f1 - f2 DPOAE is around the f2 tonotopic place with a maximum around r = 1.2 for the ZL component, while the LL component shows a decreasing trend with r. Instead, 2f2 - f1 DPOAEs show a decreasing trend with r for both ZL and LL components.
DeVries, Alexander Friedrich [Department of Radio-Oncology, Academic Teaching Hospital Feldkirch, Feldkirch (Austria); Piringer, Gudrun, E-mail: gudrun.piringer@hotmail.com [Department of Oncology, Wels-Grieskirchen Medical Hospital, Wels (Austria); Kremser, Christian; Judmaier, Werner [Department of Radiology, Innsbruck Medical University, Innsbruck (Austria); Saely, Christoph Hubert [Department of Medicine and Cardiology, Academic Teaching Hospital Feldkirch, Feldkirch (Austria); Lukas, Peter [Department of Radio-Oncology, Innsbruck Medical University, Innsbruck (Austria); Öfner, Dietmar [Department of Surgery, Paracelsus Medical University, Salzburg (Austria)
2014-12-01
Purpose: To investigate the prognostic value of the perfusion index (PI), a microcirculatory parameter estimated from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), which integrates information on both flow and permeability, to predict overall survival and disease-free survival in patients with primary rectal cancer. Methods and Materials: A total of 83 patients with stage cT3 rectal cancer requiring neoadjuvant chemoradiation were investigated with DCE-MRI before start of therapy. Contrast-enhanced dynamic T{sub 1} mapping was obtained, and a simple data analysis strategy based on the calculation of the maximum slope of the tissue concentration–time curve divided by the maximum of the arterial input function was used as a measure of tumor microcirculation (PI), which integrates information on both flow and permeability. Results: In 39 patients (47.0%), T downstaging (ypT0-2) was observed. During a mean (±SD) follow-up period of 71 ± 29 months, 58 patients (69.9%) survived, and disease-free survival was achieved in 45 patients (54.2%). The mean PI (PImean) averaged over the group of nonresponders was significantly higher than for responders. Additionally, higher PImean in age- and gender-adjusted analyses was strongly predictive of therapy nonresponse. Most importantly, PImean strongly and significantly predicted disease-free survival (unadjusted hazard ratio [HR], 1.85 [ 95% confidence interval, 1.35-2.54; P<.001)]; HR adjusted for age and sex, 1.81 [1.30-2.51]; P<.001) as well as overall survival (unadjusted HR 1.42 [1.02-1.99], P=.040; HR adjusted for age and sex, 1.43 [1.03-1.98]; P=.034). Conclusions: This analysis identifies PImean as a novel biomarker that is predictive for therapy response, disease-free survival, and overall survival in patients with primary locally advanced rectal cancer.
Sex ratios in fetuses and liveborn infants with autosomal aneuploidy
Heuther, C.A.; Martin, R.L.M.; Stoppelman, S.M. [Univ. of Cincinnati, OH (United States)] [and others
1996-06-14
Ten data sources were used substantially to increase the available data for estimating fetal and livebirth sex ratios for Patau (trisomy 13), Edwards (trisomy 18), and Down (trisomy 21) syndromes and controls. The fetal sex ratio estimate was 0.88 (N = 584) for trisomy 13, 0.90 (N = 1702) for trisomy 18, and 1.16 (N = 3154) for trisomy 21. All were significantly different from prenatal controls (1.07). The estimated ratios in prenatal controls were 1.28 (N = 1409) for CVSs and 1.06 (N = 49427) for amniocenteses, indicating a clear differential selection against males, mostly during the first half of fetal development. By contrast, there were no sex ratio differences for any of the trisomies when comparing gestational ages <16 and >16 weeks. The livebirth sex ratio estimate was 0.90 (N = 293) for trisomy 13, 0.63 (N = 497) for trisomy 18, and 1.15 (N = 6424) for trisomy 21, the latter two being statistically different than controls (1.05) (N = 3660707). These ratios for trisomies 13 and 18 were also statistically different than the ratio for trisomy 21. Only in trisomy 18 did the sex ratios in fetuses and livebirths differ, indicating a prenatal selection against males >16 weeks. No effects of maternal age or race were found on these estimates for any of the fetal or livebirth trisomies. Sex ratios for translocations and mosaics were also estimated for these aneuploids. Compared to previous estimates, these results are less extreme, most likely because of larger sample sizes and less sample bias. They support the hypothesis that these trisomy sex ratios are skewed at conception, or become so during embryonic development through differential intrauterine selection. The estimate for Down syndrome livebirths is also consistent with the hypothesis that its higher sex ratio is associated with paternal nondisjunction. 36 refs., 5 tabs.
Flash Infrared Thermography Contrast Data Analysis Technique
Koshti, Ajay
2014-01-01
This paper provides information on an IR Contrast technique that involves extracting normalized contrast versus time evolutions from the flash thermography inspection infrared video data. The analysis calculates thermal measurement features from the contrast evolution. In addition, simulation of the contrast evolution is achieved through calibration on measured contrast evolutions from many flat-bottom holes in the subject material. The measurement features and the contrast simulation are used to evaluate flash thermography data in order to characterize delamination-like anomalies. The thermal measurement features relate to the anomaly characteristics. The contrast evolution simulation is matched to the measured contrast evolution over an anomaly to provide an assessment of the anomaly depth and width which correspond to the depth and diameter of the equivalent flat-bottom hole (EFBH) similar to that used as input to the simulation. A similar analysis, in terms of diameter and depth of an equivalent uniform gap (EUG) providing a best match with the measured contrast evolution, is also provided. An edge detection technique called the half-max is used to measure width and length of the anomaly. Results of the half-max width and the EFBH/EUG diameter are compared to evaluate the anomaly. The information provided here is geared towards explaining the IR Contrast technique. Results from a limited amount of validation data on reinforced carbon-carbon (RCC) hardware are included in this paper.