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Sample records for marek osiski weng

  1. Marek Kiisa 9 ametit / Marek Kiisa ; interv. Jaana Liigand

    Index Scriptorium Estoniae

    Kiisa, Marek

    2006-01-01

    Kataloogifirma Miss Mary of Sweden juhatuse esimees oma karjäärist, juhtimiskogemustest ning Eesti ja Rootsi organisatsioonimudelitest. Vt. samas: Marek Kiisa; Katrin Verniku lühiintervjuud Marek Kiisaga

  2. Evaluation of stream discharges measurement using radioisotope and conventional method at Sungai Weng catchment area, Kedah

    International Nuclear Information System (INIS)

    Nazrul Hizam Yusoff and Wan Zakaria Wan MuhdTahir

    2006-01-01

    A number of discharge measurements using radioisotope and current metering techniques at selected streams in Sg. Weng Experimental Catchment were conducted by MINT and JPS gauging teams starting from 2003-2005. This study aims to prepare stage-discharge relationships or rating curves of the selected streams during variable flow conditions. The rating curve of the stream is one of the important parameters and usually appraised in certain routine operations of hydrological studies. It may be used in the planning of water resources management and flood control scheme. The radioisotope method employed in this study involved the injection of short-lived radioisotope tracer, that is, technetium-99m ( 99m Tc having its half-life ∼ 6.023 hrs) which was supplied from a high activity technetium generator (55.5 Gbq). Measurement of stream discharges were concurrently undertaken by JPS staff using a current meter type 0TT-C2 mounted on a wading rod at selected gauging stations for comparison purposes. Methodologies from the two methods of discharge measurements, comparison of results and identifying the uncertainties (errors) in performing the measurement during low, medium and high turbulent flows were explained in this paper. Generally, the entire results of streamflow data (2003-2005) measured by both methods during low flows (Q 3 /s) exhibit almost comparable values to each other. However, for moderate flows (1.0 m 3 /s 3 /s), the different in gauging results are slightly higher using radioisotope method ( i.e. Q isotope > Q current meter and may goes up to 40%) , and during high turbulent flows (Q>6.0 m 3 /s) the radioisotope method presented more than 40% higher discharge values as compared to the measurement made by the conventional current-meter. Observation made on site anticipated that inaccurate gauging data measured by conventional means during high flow and turbulent conditions are expected. The average estimated measurement error associated with isotope method

  3. Marek Strandberg : Rändjutlustaja või hull leiutaja? / Marek Strandberg ; interv. Piret Tali

    Index Scriptorium Estoniae

    Strandberg, Marek, 1965-

    2005-01-01

    Marek Strandberg vastab küsimustele oma praeguse tegevuse, europarlamendi valimistel kandideerimise, rohelise liikumise, Eesti Looduse Fondi toimimise kohta. Vt. samas: Strandberg joonistab ideed selgeks

  4. Marek Strandberg - rohelise tee mees / Marek Strandberg ; interv. Toomas Jüriado

    Index Scriptorium Estoniae

    Strandberg, Marek, 1965-

    2004-01-01

    Euroopa Parlamendi saadikukandidaat Marek Strandberg propageerib kolmanda, rohelise tee valikut Eesti ja Euroopa jaoks, mis tähendab uute loodussõbralike tehnoloogiate rakendamist. Lisa: Eesti keskkonnaindikaatorid

  5. Richard Wollheim 1923-2003 / Marek Volt

    Index Scriptorium Estoniae

    Volt, Marek

    2004-01-01

    Järelehüüe anglo-ameerika filosoofile Richard Wollheimile (5. V 1923-4. XI 2003), kes huvitus maalist ja psühhoanalüüsist ning kuulub XX sajandi analüütilist kunstifilosoofiat enim kujundanud filosoofide hulka. Tema peamised tööd: "Art and Its Objects" (1968), "Painting As an Art" (1987), "On Painting and the Self" (1992). Ilmunud ka raamatus: Volt, Marek. Esteetikast. Tallinn : Sirp, 2006

  6. Seroprevalence of Marek's Disease Virus antibody in some poultry ...

    African Journals Online (AJOL)

    This study reports a survey of Marek's disease virus (MDV) antibody done in 21 selected poultry flocks in Lagos, Ogun and Oyo states of southwestern Nigeria. A total of 315 serum samples were examined using the Enzyme Linked Immunosorbent Assay (ELISA) technique. Marek's disease virus antibody was present in ...

  7. 9 CFR 113.330 - Marek's Disease Vaccines.

    Science.gov (United States)

    2010-01-01

    ..., negative for Marek's disease virus antibodies, and from the same source, shall be isolated into the...) Specific pathogen free chickens or embryos, negative for Marek's disease antibodies, and from the same... diluent according to the label recommendations, and held in an ice bath at 0°C to 4°C for 2 hours prior to...

  8. Marek Demjanov : minu roll on inimestele elamusi pakkuda / Marek Demjanov ; interv. Jaana Pikalev

    Index Scriptorium Estoniae

    Demjanov, Marek

    2007-01-01

    Ilmunud ka: Delovõje Vedomosti : Vkus Zhizni, 31. jaan. 2007, lk. 2. Küsimustele karjääri kohta vastab Vene Draamateatri direktor ja restorani Sushi House üks omanikke Marek Demjanov. CV. Kommenteerib Armin Kõomägi

  9. Marek Piestrak loodab, et parim film on veel tegemata / Marek Piestrak ; interv. Urmas Lauri

    Index Scriptorium Estoniae

    Piestrak, Marek

    2008-01-01

    Haapsalu õudusfilmide festivalile HÕFF oli kutsutud poola režissöör Marek Piestrak, kes lavastas Stanislaw Lemi teose järgi Poola ja Tallinnfilmi ühistööna ulmefilmi "Navigaator Prix" (1978). Režissöör meenutab koostööd eestlastega, mida jagus kolmeks filmiks

  10. Kultuuri on üha rohkem, mõtestamist aina vähem / Marek Tamm ; intervjueerinud Heili Sibrits

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2017-01-01

    Intervjuu Marek Tammega kuluurist, kultuuri uurimisest ja kultuuri mõistest. Tallinna Ülikooli kirjastuselt ilmunud kogumikust "Kuidas uurida kultuuri? Kultuuriteaduste metodoloogia", koostajaks kultuuriajaloo professor Marek Tamm

  11. Vene Teatri juht Marek Demjanov vaatab tänasesse päeva / Marek Demjanov ; interv. Andres Keil

    Index Scriptorium Estoniae

    Demjanov, Marek

    2006-01-01

    Teatri remondi käigust, pikemalt kevadel Moskvast naasvatest noortest näitlejatest (õppisid neli aastat Moskva Kunstiteatri koolstuudios), publikust. Lisatud Marek Demjanovi eluloolised andmed ja Vene Teatri tegevuskava 2006

  12. 76 FR 66032 - Availability of an Environmental Assessment for Field Testing Avian Influenza-Marek's Disease...

    Science.gov (United States)

    2011-10-25

    ... Avian Influenza-Marek's Disease Vaccine, H5 Subtype, Serotype 3, Live Marek's Disease Vector AGENCY... authorization to ship for the purpose of field testing, and then to field test, an unlicensed Avian Influenza... product: Requester: Biomune Company. Product: Avian Influenza-Marek's Disease Vaccine, H5 Subtype...

  13. An MHC class I immune evasion gene of Marek׳s disease virus.

    Science.gov (United States)

    Hearn, Cari; Preeyanon, Likit; Hunt, Henry D; York, Ian A

    2015-01-15

    Marek׳s disease virus (MDV) is a widespread α-herpesvirus of chickens that causes T cell tumors. Acute, but not latent, MDV infection has previously been shown to lead to downregulation of cell-surface MHC class I (Virology 282:198-205 (2001)), but the gene(s) involved have not been identified. Here we demonstrate that an MDV gene, MDV012, is capable of reducing surface expression of MHC class I on chicken cells. Co-expression of an MHC class I-binding peptide targeted to the endoplasmic reticulum (bypassing the requirement for the TAP peptide transporter) partially rescued MHC class I expression in the presence of MDV012, suggesting that MDV012 is a TAP-blocking MHC class I immune evasion protein. This is the first unique non-mammalian MHC class I immune evasion gene identified, and suggests that α-herpesviruses have conserved this function for at least 100 million years. Copyright © 2014 Elsevier Inc. All rights reserved.

  14. Farmers' Awareness of Marek's Disease and Biosecurity Practices in ...

    African Journals Online (AJOL)

    Farmers' Awareness of Marek's Disease and Biosecurity Practices in Poultry Production in Selected States of Nigeria. ... The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader). If you would like more information about how ...

  15. Farmers' Awareness of Marek's Disease and Biosecurity Practices in ...

    African Journals Online (AJOL)

    The relationship between Marek's disease (MD) and factors responsible for the continuous enzootic outbreaks in Nigerian poultry farms were investigated. A structured questionnaire was served to test the level of awareness of the poultry farmers in different locations in 2009. The retrieval rate was 68.0% (150/200) from ...

  16. Tähenduslik vorm ja esteetiline emotsioon : formalism analüütilises perspektiivis / Marek Volt

    Index Scriptorium Estoniae

    Volt, Marek

    2004-01-01

    Inglise kunstikriitiku Clive Belli (1881-1964) seisukohtadest raamatus "Kunst", mida peetakse formalismi teoreetiliseks õigustuseks. Ilmunud ka raamatus: Volt, Marek. Esteetikast. Tallinn : Sirp, 2006

  17. Visceral Marek's disease in white-peafowl (Pavo cristatus)

    OpenAIRE

    Blume, G.R.; Cardoso, S.P.; Oliveira, M.L.B.; Matiolli, M.P.; Gómez, S.Y.M.; Reis Júnior, J.L.; Sant'Ana, F.J.F.; Martins, N.R.S.

    2016-01-01

    ABSTRACT Marek's disease (MD) is a lymphoproliferative disorder caused by Gallid herpesvirus 2 (MDV) that infects mainly domestic gallinaceous birds although wild birds may occasionally be affected. The current report describes the anatomopathological and molecular findings of a case of MD in a white-peafowl (Pavo cristatus). The signs included apathy, hyporexia, and diarrhea. Grossly, 0.5 to 1.5cm in diameter, yellow, soft nodules were observed in the skeletal muscle, lung, kidney, air sacs,...

  18. Märkide märkaja / Marek Strandberg ; interv. Kristel Kossar

    Index Scriptorium Estoniae

    Strandberg, Marek, 1965-

    2006-01-01

    Eestimaa Looduse Fondi nõukogu esimees Marek Strandberg vastab küsimustele, mis puudutavad tema riigikriitilisust, keskkonnateadlikku eluviisi, prügi sorteerimise vajadust, Rohelise Partei algatusrühma loomist ning tema osalemist ettevõtluses. Kommenteerib kunstnik Navitrolla (Heiki Trolla). Lisad: Marek Strandberg; Strandberg linnukatastroofist; Strandberg päikesest; Strandberg naftast

  19. Henriku kroonika pole veel ammendatud / Marek Tamm, Linda Kaljundi ; intervjueerinud Valle-Sten Maiste

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2011-01-01

    Intervjuu Marek Tamme ja Linda Kaljundiga nende poolt toimetatud artiklikogumikust: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia / edited by Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham ; Burlington : Ashgate, 2011

  20. Validation of Marek's disease diagnosis and monitoring of Marek's disease vaccines from samples collected in FTA cards.

    Science.gov (United States)

    Cortes, Aneg L; Montiel, Enrique R; Gimeno, Isabel M

    2009-12-01

    The use of Flinders Technology Associates (FTA) filter cards to quantify Marek's disease virus (MDV) DNA for the diagnosis of Marek's disease (MD) and to monitor MD vaccines was evaluated. Samples of blood (43), solid tumors (14), and feather pulp (FP; 36) collected fresh and in FTA cards were analyzed. MDV DNA load was quantified by real-time PCR. Threshold cycle (Ct) ratios were calculated for each sample by dividing the Ct value of the internal control gene (glyceraldehyde-3-phosphate dehydrogenase) by the Ct value of the MDV gene. Statistically significant correlation (P FTA cards by using Pearson's correlation test. Load of serotype 1 MDV DNA was quantified in 24 FP, 14 solid tumor, and 43 blood samples. There was a statistically significant correlation between FP (r = 0.95), solid tumor (r = 0.94), and blood (r = 0.9) samples collected fresh and in FTA cards. Load of serotype 2 MDV DNA was quantified in 17 FP samples, and the correlation between samples collected fresh and in FTA cards was also statistically significant (Pearson's coefficient, r = 0.96); load of serotype 3 MDV DNA was quantified in 36 FP samples, and correlation between samples taken fresh and in FTA cards was also statistically significant (r = 0.84). MDV DNA samples extracted 3 days (t0) and 8 months after collection (t1) were used to evaluate the stability of MDV DNA in archived samples collected in FTA cards. A statistically significant correlation was found for serotype 1 (r = 0.96), serotype 2 (r = 1), and serotype 3 (r = 0.9). The results show that FTA cards are an excellent media to collect, transport, and archive samples for MD diagnosis and to monitor MD vaccines. In addition, FTA cards are widely available, inexpensive, and adequate for the shipment of samples nationally and internationally.

  1. Visceral Marek's disease in white-peafowl (Pavo cristatus

    Directory of Open Access Journals (Sweden)

    G.R. Blume

    Full Text Available ABSTRACT Marek's disease (MD is a lymphoproliferative disorder caused by Gallid herpesvirus 2 (MDV that infects mainly domestic gallinaceous birds although wild birds may occasionally be affected. The current report describes the anatomopathological and molecular findings of a case of MD in a white-peafowl (Pavo cristatus. The signs included apathy, hyporexia, and diarrhea. Grossly, 0.5 to 1.5cm in diameter, yellow, soft nodules were observed in the skeletal muscle, lung, kidney, air sacs, small intestine, heart, ovary, ventriculus, and proventriculus. Microscopically, numerous atypical round neoplastic cells were noted. The molecular detection of MDV DNA was implemented to amplify part of the meq gene and products were sequenced for the phylogenetic analysis. Template DNA was obtained from tissues of the affected bird and from blood of all the gallinaceous birds of the Zoo. The expected amplicon for the partial amplification of MDV meq gene was obtained and the amplicons were sequenced. Sequences obtained enabled grouping the strain (accession no. KT768121 with MDV serotype 1 strains from the GenBank. Based on the anatomopathological and molecular findings, the diagnosis of MD in a white-peafowl was reached, and to the authors' knowledge, no previous report regarding MD was published in Pavo cristatus.

  2. AN MHC class I immune evasion gene of Marek's disease virus

    Science.gov (United States)

    Marek's disease virus (MDV) is a widespread a-herpesvirus of chickens that causes T cell tumors. Acute, but not latent, MDV infection has previously been shown to lead to downregulation of cell-surface MHC class I (Virology 282:198–205 (2001)), but the gene(s) involved have not been identified. Here...

  3. Nõukogude propagandamasin kasutas mõjutamiseks peamiselt trükimeediat / Marek Miil ; intervjueerinud Annela Laaneots

    Index Scriptorium Estoniae

    Miil, Marek, 1976-

    2014-01-01

    Intervjuu meedi- ja kommunikatsioonieriala doktori Marek Miiliga tema Tartu Ülikoolis kaitstud doktoritööst, mis kirjeldab, kuidas nõukogude propagandasüsteem kasutas oma eesmärkide elluviimisel Nõukogude Eesti ajakirjandust. Tolleaegse propaganda mõjust ja õpetlikkusest tänapäeval, Venemaa praegusest propagandast

  4. Ajalool on ajaloolaste nägu / Jean-Claude Schmitt ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Schmitt, Jean-Claude

    2004-01-01

    Intervjuu ajaloolase Jean-Claude Schmittiga. Ilm. ka: Keha, pilt ja unenägu : intervjuu Jean-Claude Scmittiga // Schmitt, Jean-Claude. Püha hurdakoer : Guinefort - lasteravija 13. sajandist. - Tallinn, 2000. - Lk. 296-305 ; Kuidas kirjutatakse ajalugu? // Tamm, Marek. Kuidas kirjutatakse ajalugu? - Tallinn, 2007. - 161-177

  5. Molecular characterization of Marek's disease herpesvirus B antigen

    International Nuclear Information System (INIS)

    Isfort, R.J.; Sithole, I.; Kung, H.J.; Velicer, L.F.

    1986-01-01

    The Marek's disease herpesvirus (MDHV) B antigen (MDHV-B) was identified and molecularly characterized as a set of three glycoproteins of 100,000, 60,000, and 49,000 apparent molecular weight (gp100, gp60, and gp49, respectively) by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) after immunoprecipitation from [ 35 S]methionine-labeled infected cells by specific rabbit antiserum directed against MDHV-B (RαB), as previously determined by immunodiffusion. Further identification was accomplished by blocking this immunoprecipitation with highly purified MDHV-B. The same set of three polypeptides was also immunoprecipitated from [ 35 S] methionine- and 14 C-labeled infected cells into two other sera shown to have anti-B activity. These data serve to clarify the molecular identification of the polypeptides found in common between MDHV and HVT by linking them to MDHV-B. Collectively, the data presented here and by others support the conclusion that all three glycoproteins now identified as gp100, gp60, and gp49 have MDHV-B determinants. Finally, detection of the same three polypeptides with well-absorbed RαPM, which was directed against purified infected-cell plasma membranes, suggests that at least one component of the B-antigen complex has a plasma membrane location in the infected cell. These preliminary data point to the future membrane biochemistry and membrane immunology experiments needed to understand the MDHV system, and they may explain the high level of immunogenicity of MDHV-B in the infected chicken, as shown by its immunoprecipitation with immune chicken serum

  6. Industry-Wide Surveillance of Marek's Disease Virus on Commercial Poultry Farms.

    Science.gov (United States)

    Kennedy, David A; Cairns, Christopher; Jones, Matthew J; Bell, Andrew S; Salathé, Rahel M; Baigent, Susan J; Nair, Venugopal K; Dunn, Patricia A; Read, Andrew F

    2017-06-01

    Marek's disease virus is a herpesvirus of chickens that costs the worldwide poultry industry more than US$1 billion annually. Two generations of Marek's disease vaccines have shown reduced efficacy over the last half century due to evolution of the virus. Understanding where the virus is present may give insight into whether continued reductions in efficacy are likely. We conducted a 3-yr surveillance study to assess the prevalence of Marek's disease virus on commercial poultry farms, determine the effect of various factors on virus prevalence, and document virus dynamics in broiler chicken houses over short (weeks) and long (years) timescales. We extracted DNA from dust samples collected from commercial chicken and egg production facilities in Pennsylvania, USA. Quantitative PCR was used to assess wild-type virus detectability and concentration. Using data from 1018 dust samples with Bayesian generalized linear mixed effects models, we determined the factors that correlated with virus prevalence across farms. Maximum likelihood and autocorrelation function estimation on 3727 additional dust samples were used to document and characterize virus concentrations within houses over time. Overall, wild-type virus was detectable at least once on 36 of 104 farms at rates that varied substantially between farms. Virus was detected in one of three broiler-breeder operations (companies), four of five broiler operations, and three of five egg layer operations. Marek's disease virus detectability differed by production type, bird age, day of the year, operation (company), farm, house, flock, and sample. Operation (company) was the most important factor, accounting for between 12% and 63.4% of the variation in virus detectability. Within individual houses, virus concentration often dropped below detectable levels and reemerged later. These data characterize Marek's disease virus dynamics, which are potentially important to the evolution of the virus.

  7. Modeling Marek's disease virus transmission: A framework for evaluating the impact of farming practices and evolution

    OpenAIRE

    David A. Kennedy; Patricia A. Dunn; Andrew F. Read

    2018-01-01

    Marek's disease virus (MDV) is a pathogen of chickens whose control has twice been undermined by pathogen evolution. Disease ecology is believed to be the main driver of this evolution, yet mathematical models of MDV disease ecology have never been confronted with data to test their reliability. Here, we develop a suite of MDV models that differ in the ecological mechanisms they include. We fit these models with maximum likelihood using iterated filtering in ‘pomp’ to data on MDV concentratio...

  8. First molecular detection and characterization of Marek's disease virus in red-crowned cranes (Grus japonensis): a case report.

    Science.gov (United States)

    Lian, Xue; Ming, Xin; Xu, Jiarong; Cheng, Wangkun; Zhang, Xunhai; Chen, Hongjun; Ding, Chan; Jung, Yong-Sam; Qian, Yingjuan

    2018-04-03

    Marek's disease virus (MDV) resides in the genus Mardivirus in the family Herpesviridae. MDV is a highly contagious virus that can cause neurological lesions, lymphocytic proliferation, immune suppression, and death in avian species, including Galliformes (chickens, quails, partridges, and pheasants), Strigiformes (owls), Anseriformes (ducks, geese, and swans), and Falconiformes (kestrels). In 2015, two red-crowned cranes died in Nanjing (Jiangsu, China). It was determined that the birds were infected with Marek's disease virus by histopathological examination, polymerase chain reaction (PCR), gene sequencing and sequence analysis of tissue samples from two cranes. Gross lesions included diffuse nodules in the skin, muscle, liver, spleen, kidney, gizzard and heart, along with liver enlargement and gizzard mucosa hemorrhage. Histopathological assay showed that infiltrative lymphocytes and mitotic figures existed in liver and heart. The presence of MDV was confirmed by PCR. The sequence analysis of the Meq gene showed 100% identity with Md5, while the VP22 gene showed the highest homology with CVI988. Furthermore, the phylogenetic analysis of the VP22 and Meq genes suggested that the MDV (from cranes) belongs to MDV serotype 1. We describe the first molecular detection of Marek's disease in red-crowned cranes based on the findings previously described. To our knowledge, this is also the first molecular identification of Marek's disease virus in the order Gruiformes and represents detection of a novel MDV strain.

  9. Mida oled sina teinud, et Internet oleks senisest ohutum? / Helin Puksand, Peter Fifka, Marek Strandberg, Birgy Lorenz...[jt.

    Index Scriptorium Estoniae

    2008-01-01

    Küsimusele vastavad Tallinna Mustamäe Gümnaasiumi eesti keele õpetaja Helin Puksand, Microsofti esindaja Peter Fifka, riigikogu liige Marek Strandberg, Pelgulinna Gümnaasiumi arvutiõpetaja Birgy Lorenz, Tallinna Ülikooli haridustehnoloogia keskuse juhataja Mart Laanpere, teleajakirjanik Andres Raid ja Kose Gümnaasiumi saksa keele õpetaja Astrid Sildnik

  10. Titration of Marek's disease cell-associated vaccine virus (CVI 988) of reconstituted vaccine and vaccine ampoules from dutch hatcheries

    NARCIS (Netherlands)

    Landman, W.J.M.; Pritz-Verschuren, S.B.E.

    2003-01-01

    SUMMARY. Thirty-one outbreaks of Marek¿s disease (MD) were reported in the Netherlands and retrospectively analyzed. The outbreaks occurred mostly in vaccinated commercial layer and a few breeder flocks of several breeds; however, the cause of the outbreaks could not be stablished. Therefore, in a

  11. Marek Biesiada

    Indian Academy of Sciences (India)

    Abstract. In this paper, we consider the mysterious optical transient. SCP 06F6 displaying a symmetric light curve with a (half-time) duration of about 100 days. The projected location of the event falls close to the center of the galaxy cluster CL 1432.5 + 332.8 lying at the redshift z = 1.112. Guided by suggestive symmetry of ...

  12. Route of challenge is critical in determining the clinical outcome of infection with a very virulent oncogenic herpesvirus, Marek's disease virus.

    OpenAIRE

    Butter , Colin; Staines , Karen; Baaten , Bas; Smith , Lorraine; Davison , Fred

    2007-01-01

    Abstract Susceptible (Line 7) and resistant (Line 6) white leghorn chickens were infected with a very virulent Marek?s Disease Virus, RB1B, by either the intra-abdominal or intra-tracheal routes. Birds infected by the intra-tracheal route had earlier, higher or more sustained blood, spleen and lung viral loads, than those infected by the intra-peritoneal route. Line 7 birds had higher viral loads than Line 6 birds infected by the same route. Clinical outcomes reflected these ...

  13. Telomerase Activity in Chicken EmbryoFibroblast Cell Cultures Infected withMarek's Disease Virus

    Directory of Open Access Journals (Sweden)

    Gregory A. Tannock

    2010-07-01

    Full Text Available Background:Telomerase is a ribonucleoprotein, which adds telomeric repeats onto the 3’end of existing telomers at the end of chromosomes ineukaryotes. One hypothesis states that telomere length may function as a mitoticclock, therefore expression of telomerase activity in cancer cells may be a necessary and essential step for tumor development and progression.Methods:The detectability of telomerase activity in chicken embryofibroblast (CEF cells infected with different passages of Marek's disease virus(MDV was tested with the TRAPEZE® telomerase detection kit at passages14 (P14, P80/1 and P120 for the Woodland strain, and passage 9 (P9 for theMPF57 strain. Results:The results showed increased telomerase activity in MDV Woodlands strain at P14 and MPF57 strain at P9. Conclusion:Our results suggest that MDV-transformed cells at low passage are a suitable system for the study of telomerases in tumor developmentand for testing telomerase-inhibiting drugs.

  14. Detection of Marek's disease virus DNA in Japanese quail susceptible to atherosclerosis

    International Nuclear Information System (INIS)

    Pyrzak, R.; Shih, J.C.H.

    1986-01-01

    Marek's disease virus (MDV) was demonstrated as an etiological agent which causes atherosclerosis in the chicken. Since herpes viruses are ubiquitous, incidences of viral atherogenesis in humans and other animals were speculated. In this laboratory, the atherosclerosis susceptible (SUS) and resistant (RES) Japanese quail were developed as the animal model for atherosclerosis research. The susceptibility of the animal might be due to an infection of MDV or a related quail herpes virus (QHV). An initial attempt to isolate viruses from quail and an agar gel precipitin test for MDC were not positive. A DNA hybridization technique was used to determine whether the MDC-DNA existed in the quail cell. The gene library of MDV EcoRl DNA fragments was used to prepare the DNA probe, labeled with [ 32 P] by nick translation. Dot hybridizations were carried out by mixing the MDV-DNA probe with DNAs isolated from quail tissues. A high stringent condition was used. From this experiment it was found that the tissues from the SUS quail were hybridization positive, but most of them from RES quail were negative. When aortas were compared, the severe atherosclerotic had a strong hybridization (3-4 cop. of genome/cell) whereas the others hybridized moderately (1 cop./cell). It was concluded that genes from MDV or a QHV indeed existed in Japanese quail

  15. Pathogenicity of a Very Virulent Strain of Marek's Disease Herpesvirus Cloned as Infectious Bacterial Artificial Chromosomes

    Directory of Open Access Journals (Sweden)

    Lorraine P. Smith

    2011-01-01

    Full Text Available Bacterial artificial chromosome (BAC vectors containing the full-length genomes of several herpesviruses have been used widely as tools to enable functional studies of viral genes. Marek's disease viruses (MDVs are highly oncogenic alphaherpesviruses that induce rapid-onset T-cell lymphomas in chickens. Oncogenic strains of MDV reconstituted from BAC clones have been used to examine the role of viral genes in inducing tumours. Past studies have demonstrated continuous increase in virulence of MDV strains. We have previously reported on the UK isolate C12/130 that showed increased virulence features including lymphoid organ atrophy and enhanced tropism for the central nervous system. Here we report the construction of the BAC clones (pC12/130 of this strain. Chickens were infected with viruses reconstituted from the pC12/130 clones along with the wild-type virus for the comparison of the pathogenic properties. Our studies show that BAC-derived viruses induced disease similar to the wild-type virus, though there were differences in the levels of pathogenicity between individual viruses. Generation of BAC clones that differ in the potential to induce cytolytic disease provide the opportunity to identify the molecular determinants of increased virulence by direct sequence analysis as well as by using reverse genetics approaches on the infectious BAC clones.

  16. Toetuseta jäämine šokeeris mainekat kultuuriajakirja / Ott Raun, Laine Jänes ; interv. Rebekka Lotman ; komment. Marek Tamm

    Index Scriptorium Estoniae

    Raun, Ott, 1940-

    2009-01-01

    Eesti Kultuurkapitalinõukogu otsusel jääb ajalookultuuri ajakiri "Tuna" alates 2009. aastast püsitoetusest ilma. Sellega seotud küsimustele vastavad "Tuna" peatoimetaja Ott Raun ja Eesti Kultuurkapitali nõukogu esimees Laine Jänes, kommenteerinud ajaloolane Marek Tamm

  17. Standardization of a model to study revaccination against Marek's disease under laboratory conditions.

    Science.gov (United States)

    Gimeno, Isabel M; Witter, Richard L; Cortes, Aneg L; Reddy, Sanjay M; Pandiri, Arun R

    2012-01-01

    Revaccination, the practice of administering Marek's disease (MD) vaccine a second time, has been used in commercial poultry flocks for many years. The rationale is largely anecdotal as the few published reports have failed to provide support for the value of the practice. In the present work, we have standardized a model to study MD revaccination under laboratory conditions. Nine bird experiments were conducted to evaluate homologous revaccination (same vaccine administered twice) and heterologous revaccination (administration of two different vaccines) with various challenge models. Our results demonstrated that heterologous revaccination (with a second vaccine more protective than the first vaccine) but not homologous revaccination provided a beneficial increase in protection. Administration of the first vaccine at 18 days of embryonation followed by a more protective second vaccine at hatch reproduced systematically the benefits of revaccination. In addition, our results show that revaccination protocols might aid in solving major drawbacks associated with various highly protective experimental MD vaccines; that is, lymphoid organ atrophy and residual virulence. Strain RM1 is one of the most protective vaccines against early challenge with highly virulent MD virus but it induces severe lymphoid atrophy in chickens lacking maternal antibodies against MD virus. In this study, strain RM1 did not induce lymphoid organ atrophy when administered as second vaccine in a revaccination protocol. Similarly, strain 648A100/BP5 maintains residual virulence in chickens lacking maternal antibodies against MD virus but did not induce any lesions when used as a second vaccine. Until now, arbitrary revaccination protocols have been occasionally proven useful to the poultry industry. The model developed in this study will allow for a better understanding of this phenomenon and its optimization. A more rational use of this practice will be of great help to control MD outbreaks

  18. Association of Marek's Disease induced immunosuppression with activation of a novel regulatory T cells in chickens.

    Directory of Open Access Journals (Sweden)

    Angila Gurung

    2017-12-01

    Full Text Available Marek's Disease Virus (MDV is an alphaherpesvirus that infects chickens, transforms CD4+ T cells and causes deadly lymphomas. In addition, MDV induces immunosuppression early during infection by inducing cell death of the infected lymphocytes, and potentially due to activation of regulatory T (Treg-cells. Furthermore, immunosuppression also occurs during the transformation phase of the disease; however, it is still unknown how the disease can suppress immune response prior or after lymphoma formation. Here, we demonstrated that chicken TGF-beta+ Treg cells are found in different lymphoid tissues, with the highest levels found in the gut-associated lymphoid tissue (cecal tonsil: CT, fostering an immune-privileged microenvironment exerted by TGF-beta. Surprisingly, significantly higher frequencies of TGF-beta+ Treg cells are found in the spleens of MDV-susceptible chicken lines compared to the resistant line, suggesting an association between TGF-beta+ Treg cells and host susceptibility to lymphoma formation. Experimental infection with a virulent MDV elevated the levels of TGF-beta+ Treg cells in the lungs as early as 4 days post infection, and during the transformation phase of the disease in the spleens. In contrast to TGF-beta+ Treg cells, the levels of CD4+CD25+ T cells remained unchanged during the infection and transformation phase of the disease. Furthermore, our results demonstrate that the induction of TGF-beta+ Treg cells is associated with pathogenesis of the disease, as the vaccine strain of MDV did not induce TGF-beta+ Treg cells. Similar to human haematopoietic malignant cells, MDV-induced lymphoma cells expressed high levels of TGF-beta but very low levels of TGF-beta receptor I and II genes. The results confirm that COX-2/ PGE2 pathway is involved in immunosuppression induced by MDV-lymphoma cells. Taken together, our results revealed a novel TGF-beta+ Treg subset in chickens that is activated during MDV infection and tumour

  19. History of the First-Generation Marek's Disease Vaccines: The Science and Little-Known Facts.

    Science.gov (United States)

    Schat, Karel A

    2016-12-01

    Shortly after the isolation of Marek's disease (MD) herpesvirus (MDV) in the late 1960s vaccines were developed in England, the United States, and The Netherlands. Biggs and associates at the Houghton Poultry Research Station (HPRS) in England attenuated HPRS-16, the first cell-culture-isolated MDV strain, by passaging HPRS-16 in chick kidney cells. Although HPRS-16/Att was the first commercially available vaccine, it never became widely used and was soon replaced by the FC126 strain of herpesvirus of turkeys (HVT) vaccine developed by Witter and associates at the Regional Poultry Research Laboratory (now Avian Disease and Oncology Laboratory [ADOL]) in East Lansing, MI. Ironically, Kawamura et al. isolated a herpesvirus from kidney cell cultures from turkeys in 1969 but never realized its potential as a vaccine against MD. Rispens of the Central Veterinary Institute (CVI) developed the third vaccine. His associate, Maas, had found commercial flocks of chickens with MDV antibodies but without MD. Subsequently, Rispens isolated a very low pathogenic strain from hen number 988 from his MD antibody-positive flock, which was free of avian leukosis virus and clinical MD. This isolate became the CVI-988 vaccine used mostly in The Netherlands. During the late 1970s, HVT was no longer fully protective against some new emerging field strains. The addition of SB-1, isolated by Schat and Calnek, to HVT improved protection against the emerging very virulent strains. In the 1990s CVI-988 became the worldwide vaccine gold standard. This review will present data from published papers and personal communications providing additional information about the exciting 15-yr period after the isolation of MDV to the development of the different vaccines.

  20. Mutations within ICP4 acquired during in vitro attenuation do not alter virulence of recombinant Marek's disease viruses in vivo

    Directory of Open Access Journals (Sweden)

    Evin Hildebrandt

    2015-12-01

    Full Text Available Marek's disease (MD is a T-cell lymphoma of chickens caused by the oncogenic Marek's disease virus (MDV. MD is primarily controlled by live-attenuated vaccines generated by repeated in vitro serial passage. Previous efforts to characterize attenuated MDVs identified numerous mutations, particularly a convergence of high-frequency mutations around amino acids 60–63 within ICP4 (RS1, therefore, ICP4 was considered a candidate gene deserving further characterization. Recombinant MDVs were generated containing a single Q63H mutation or double Q63H + S1630P mutations. Despite the repetitive nature of mutations within ICP4, neither recombinant virus decreased virulence, although one mutant reduced in vivo replication and failed to transmit horizontally. Our results indicate that these mutations are insufficient to reduce disease incidence in infected birds, and suggest that variants in ICP4 do not directly alter virulence, but rather may enhance MDV replication rates in vitro, offering an explanation for the widespread occurrence of ICP4 mutations in a variety of attenuated herpesviruses.

  1. [Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia. Hrsg. von Marek Tamm, Linda Kaljundi, Carsten Selch Jensen] / Volker Honemann

    Index Scriptorium Estoniae

    Honemann, Volker, 1943-

    2013-01-01

    Arvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia. Hrsg. von Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Verlag Ashgate. Farnham, 2011

  2. Morphology of immune organs after very virulent plus strain of Marek's disease virus infection in vaccinated hens.

    Science.gov (United States)

    Madej, J P; Woźniakowski, G; Gaweł, A

    2016-01-01

    Marek's disease (MD) outbreaks in poultry flocks may be associated with overriding of vaccine immune protection by very virulent (vvMDV) or very virulent plus (vv+MDV) strains. This paper presents the study on lymphoid organ morphology in the latent phase of MD caused by vv+MDV which break post-vaccinal protection in hens. We also immunohistochemically examined B and T populations as well as B/T and CD4+/CD8+ ratio of lymphocytes in lymphatic organs and, as a background, in MD lymphomas from non-lymphatic organs. The number of antigen expressed cells was evaluated as a percentage of positive cells in the one power field. Organ samples were collected from 24 dead reproductive hens (Ross 308 line) in age between 35-56 weeks, infected with vv+MDV. The hens originated from farms with MD outbreaks, despite earlier routine vaccination with CVI988/Rispens + HVT. The control organ samples originated from 15 clinically healthy hens at the same age and line, subjected to the same vaccination schedule. The number of CD3+, CD8+ and TCRγδ+ cells was significantly lower in MDV infected thymus, spleen and cecal tonsils in comparison to that found in the control organs. The proportion of CD4+ was also distinctly reduced in the thymus and limited in the spleen of MDV infected hens. This study revealed that infection with field vv+MDV isolates might break post-vaccinal protection and influence the central and peripheral immune system. The decrease in CD8+ and TCRγδ+ cell number in the thymus, spleen and cecal tonsils suggests that primarily these cells are involved in cell-mediated cytotoxicity against MDV transformed cells during latency.

  3. A phylogenomic analysis of Marek's disease virus reveals independent paths to virulence in Eurasia and North America.

    Science.gov (United States)

    Trimpert, Jakob; Groenke, Nicole; Jenckel, Maria; He, Shulin; Kunec, Dusan; Szpara, Moriah L; Spatz, Stephen J; Osterrieder, Nikolaus; McMahon, Dino P

    2017-12-01

    Virulence determines the impact a pathogen has on the fitness of its host, yet current understanding of the evolutionary origins and causes of virulence of many pathogens is surprisingly incomplete. Here, we explore the evolution of Marek's disease virus (MDV), a herpesvirus commonly afflicting chickens and rarely other avian species. The history of MDV in the 20th century represents an important case study in the evolution of virulence. The severity of MDV infection in chickens has been rising steadily since the adoption of intensive farming techniques and vaccination programs in the 1950s and 1970s, respectively. It has remained uncertain, however, which of these factors is causally more responsible for the observed increase in virulence of circulating viruses. We conducted a phylogenomic study to understand the evolution of MDV in the context of dramatic changes to poultry farming and disease control. Our analysis reveals evidence of geographical structuring of MDV strains, with reconstructions supporting the emergence of virulent viruses independently in North America and Eurasia. Of note, the emergence of virulent viruses appears to coincide approximately with the introduction of comprehensive vaccination on both continents. The time-dated phylogeny also indicated that MDV has a mean evolutionary rate of ~1.6 × 10 -5 substitutions per site per year. An examination of gene-linked mutations did not identify a strong association between mutational variation and virulence phenotypes, indicating that MDV may evolve readily and rapidly under strong selective pressures and that multiple genotypic pathways may underlie virulence adaptation in MDV.

  4. Critical role of the virus-encoded microRNA-155 ortholog in the induction of Marek's disease lymphomas.

    Directory of Open Access Journals (Sweden)

    Yuguang Zhao

    2011-02-01

    Full Text Available Notwithstanding the well-characterised roles of a number of oncogenes in neoplastic transformation, microRNAs (miRNAs are increasingly implicated in several human cancers. Discovery of miRNAs in several oncogenic herpesviruses such as KSHV has further highlighted the potential of virus-encoded miRNAs to contribute to their oncogenic capabilities. Nevertheless, despite the identification of several possible cancer-related genes as their targets, the direct in vivo role of virus-encoded miRNAs in neoplastic diseases such as those induced by KSHV is difficult to demonstrate in the absence of suitable models. However, excellent natural disease models of rapid-onset Marek's disease (MD lymphomas in chickens allow examination of the oncogenic potential of virus-encoded miRNAs. Using viruses modified by reverse genetics of the infectious BAC clone of the oncogenic RB-1B strain of MDV, we show that the deletion of the six-miRNA cluster 1 from the viral genome abolished the oncogenicity of the virus. This loss of oncogenicity appeared to be primarily due to the single miRNA within the cluster, miR-M4, the ortholog of cellular miR-155, since its deletion or a 2-nucleotide mutation within its seed region was sufficient to inhibit the induction of lymphomas. The definitive role of this miR-155 ortholog in oncogenicity was further confirmed by the rescue of oncogenic phenotype by revertant viruses that expressed either the miR-M4 or the cellular homolog gga-miR-155. This is the first demonstration of the direct in vivo role of a virus-encoded miRNA in inducing tumors in a natural infection model. Furthermore, the use of viruses deleted in miRNAs as effective vaccines against virulent MDV challenge, enables the prospects of generating genetically defined attenuated vaccines.

  5. Persistence of chicken anemia virus antigen and inclusions in spontaneous cases of Marek's disease visceral lymphomas in broiler chickens at slaughterhouses.

    Science.gov (United States)

    Ahmed, Mohamed Sabry; Ono, Hiroki; Sasaki, Jun; Ochiai, Kenji; Goryo, Masanobu

    2016-06-01

    The chicken anemia virus (CAV) and Marek's disease virus (MDV) infect chickens worldwide; a single or dual infection by these viruses has a great impact on poultry production. In the present study, we examined the existence of CAV antigen and its inclusions in Marek's disease (MD) lymphomas in chickens in the slaughterhouses of Iwate prefecture, Japan. Forty-nine spleens and 13 livers with different degrees of nodular lesions were histopathologically examined at our laboratory. Grossly, the tested organs showed various sizes and anatomical architectures. Based on the cellular morphology and the infiltrative nature of the neoplastic lymphocytes, MD was confirmed in 76% (37/49) of the spleens and 92% (12/13) of the livers. The lesions of MD, according to the pattern of lymphocytic accumulation in the affected organs, were divided into multifocal, coalesced and diffuse. CAV intranuclear inclusion bodies were detected within the small and the large bizarre lymphocytes of the MD lymphomas in 2 livers and 9 spleens, and the immunostaining test for CAV confirmed the persistence of CAV antigens and inclusions in the neoplastic cells. This study demonstrated the persistence of CAV infection within the neoplastic cells of naturally occurring MD lymphomas in chickens.

  6. Differential expression of Toll-like receptor pathway genes in chicken embryo fibroblasts from chickens resistant and susceptible to Marek's disease.

    Science.gov (United States)

    Haunshi, Santosh; Cheng, Hans H

    2014-03-01

    The Toll-like receptor (TLR) signaling pathway is one of the innate immune defense mechanisms against pathogens in vertebrates and invertebrates. However, the role of TLR in non-MHC genetic resistance or susceptibility to Marek's disease (MD) in the chicken is yet to be elucidated. Chicken embryo fibroblast (CEF) cells from MD susceptible and resistant lines were infected either with Marek's disease virus (MDV) or treated with polyionosinic-polycytidylic acid, a synthetic analog of dsRNA, and the expression of TLR and pro-inflammatory cytokines was studied at 8 and 36 h posttreatment by quantitative reverse transcriptase PCR. Findings of the present study reveal that MDV infection and polyionosinic-polycytidylic acid treatment significantly elevated the mRNA expression of TLR3, IL6, and IL8 in both susceptible and resistant lines. Furthermore, basal expression levels in uninfected CEF for TLR3, TLR7, and IL8 genes were significantly higher in resistant chickens compared with those of susceptible chickens. Our results suggest that TLR3 together with pro-inflammatory cytokines may play a significant role in genetic resistance to MD.

  7. Down-regulation of MHC class I by the Marek's disease virus (MDV) UL49.5 gene product mildly affects virulence in a haplotype-specific fashion.

    Science.gov (United States)

    Jarosinski, Keith W; Hunt, Henry D; Osterrieder, Nikolaus

    2010-09-30

    Marek's disease is a devastating neoplastic disease of chickens caused by Marek's disease virus (MDV). MDV down-regulates surface expression of MHC class I molecules, although the mechanism has remained elusive. MDV harbors a UL49.5 homolog that has been shown to down-regulate MHC class I expression in other Varicelloviruses. Using in vitro assays, we showed that MDV pUL49.5 down-regulates MHC class I directly and identified its cytoplasmic tail as essential for this function. In vivo, viruses lacking the cytoplasmic tail of pUL49.5 showed no differences in MD pathogenesis compared to revertant viruses in highly susceptible chickens of the B(19)B(19) MHC class I haplotype, while there was a mild reduction in pathogenic potential of the deletion viruses in chickens more resistant to MD pathogenesis (MHC:B(21)B(21)). We concluded that the pathogenic effect of MHC class I down-regulation mediated by pUL49.5 is small because virus immune evasion possibly requires more than one viral protein. Copyright 2010 Elsevier Inc. All rights reserved.

  8. A deletion within glycoprotein L of Marek's disease virus (MDV) field isolates correlates with a decrease in bivalent MDV vaccine efficacy in contact-exposed chickens.

    Science.gov (United States)

    Tavlarides-Hontz, Phaedra; Kumar, Pankaj M; Amortegui, Juliana Rojas; Osterrieder, Nikolaus; Parcells, Mark S

    2009-06-01

    We examined the functional role of a naturally occurring deletion within the glycoprotein L (gL) gene of Marek's disease virus (MDV) field isolates. We previously showed that this mutation incrementally increased the virulence of an MDV in contact-exposed SPF leghorn chickens, when chickens shedding this virus were co-infected with herpesvirus of turkeys (HVT). In our present study, we examined this mutation using two stocks of the very virulent plus (vv+)MDV strain TK, one of which harbored this deletion (TK1a) while the other did not (TK2a). We report that TK1a replicating in vaccinated chickens overcame bivalent (HVT/SB1) vaccine protection in contact-exposed chickens. Treatment groups exposed to vaccinated chickens inoculated with a 1:1 mix of TK1a and TK2a showed decreased bivalent vaccine efficacy, and this decrease correlated with the prevalence of the gL deletion indicative of TK1a. These results were also found using quadruplicate treatment groups and bivalently vaccinated chickens obtained from a commercial hatchery. As this deletion was found in 25 out of 25 recent field isolates from Delaware, Maryland, North Carolina, Pennsylvania, and Virginia, we concluded that there is a strong selection for this mutation, which appears to have evolved in HVT or bivalently vaccinated chickens. This is the first report of a mutation in a vv+MDV field strain for which a putative biological phenotype has been discerned. Moreover, this mutation in gL has apparently been selected in MDV field isolates through Marek's disease vaccination.

  9. Meeleparanduslik teater / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2006-01-01

    Autor tunneb muret ühe uue tendentsi pärast, mida kohtab nii teatri NO99 ja Von Krahli viimastes lavastustes ("Nafta" ja "Võluflööt") kui teisteski teatrites (Linnateatri "Genoom"). Seda tendentsi nimetab ta "meeleparanduslikuks teatriks" ja näeb selles mitmeid probleeme

  10. Pop / Marek Kallin

    Index Scriptorium Estoniae

    Kallin, Marek

    2002-01-01

    Heliplaatidest Mobb Deep "Infamy". Hilmar Örn Hilmarsson & Sigur Ros "Angels Of The Universe". Simple Minds"The Best of". Angie Stone "Mahogany Soul". Cypress Hill "Stoned Raiders". Bebel Gilberto "Tanto Tempo Remixes". Roots Manuva "Run Come Save Me"

  11. Pop / Marek Kallin

    Index Scriptorium Estoniae

    Kallin, Marek

    2003-01-01

    Heliplaatidest: Myslovitz "Korova Milky Bar", Sting "Sacred Love", Erinevad esitajad "Complications. Exogenic Breaks Compilation vol.1", Erinevad esitajad "An Anthology of Noise & Electronic Music Volume #2", Headphone Science "We Remain Faded", Mark Eitzel "The Ugly American"

  12. Pop / Marek Kallin

    Index Scriptorium Estoniae

    Kallin, Marek

    2005-01-01

    Heliplaatidest: Kano "Home Sweet Home", Static-X "Start A War", Kraftwerk "Minimum Maximum", The Juan Maclean "Less Than Human", Andrian Belew "Side Two", Saint Etienne "Tales From Turnpike House", Jamie Cullum "Pointless Nostalgic", James Blunt "Back To Bedlam", Architecture In Helsinki "In Case We Die"

  13. Uued heliplaadid / Marek Kallin

    Index Scriptorium Estoniae

    Kallin, Marek

    1999-01-01

    Heliplaatide tutvustus : Sixpence None The Richer "Sixpence None The Richer", Erinevad esitajad "No Boundaries - A Benefit For The Kosovar Refugees", K-Ci & JoJo "It's Real", Limp Bizkit "Significant Other"

  14. Pop / Marek Kallin

    Index Scriptorium Estoniae

    Kallin, Marek

    2005-01-01

    Heliplaatidest: Cardigans "Super Extra Gravity", Earth, Wind & Fire "Illumination", Stevie Wonder "A Time To Love", Shout Out Louds "Howl Howl Gaff Gaff", Goldie Lookin Chain "Safe As Fuck", Ms. Dynamite "Judgement Days", Echosilence "Distorted Horizon", Bob Dylan "No Direction Home"

  15. [Uued heliplaadid] / Marek Kallin

    Index Scriptorium Estoniae

    Kallin, Marek

    1999-01-01

    Uutest heliplaatidest: The Cranberries "Bury The Hatchet", Naughty By Nature "Nineteen Naughty Nine: Nature"s Fury", erinevad esitajad "INCredible Sound of Drum"n"Bass: Mixed by Goldie", New Radicals "Maybe You"ve Been Brainwashed Too"

  16. Lugemisnoppeid: antropoloogia / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2012-01-01

    Tutvustus: Jürgenson, Aivar. Ladina rahva seas : Argentina ja sealsed eestlased. Tallinn, 2011 ; Annist, Aet. Otsides kogukonda sotsialismijärgses keskuskülas : arenguantropoloogiline uurimus. Tallinn : Tallinna Ülikooli Kirjastus, 2011. (Acta Universitatis Tallinnensis. Socialia) ; Hiiemäe, Reet. Kaitsemaagia eesti rahvausundis. Tallinn, 2012 ; Augé, Marc. Kohad ja mittekohad : sissejuhatus ülimodernsuse antropoloogiasse. Tallinn : Tallinna Ülikooli Kirjastus, 2012. (Bibliotheca controversiarum)

  17. Quantitation of Marek's disease and chicken anemia viruses in organs of experimentally infected chickens and commercial chickens by multiplex real-time PCR.

    Science.gov (United States)

    Davidson, Irit; Raibshtein, I; Al-Touri, A

    2013-06-01

    The worldwide distribution of chicken anemia virus (CAV) and Marek's disease virus (MDV) is well documented. In addition to their economic significance in single- or dual-virus infections, the two viruses can often accompany various other pathogens and affect poultry health either directly, by causing tumors, anemia, and delayed growth, or indirectly, by aggravating other diseases, as a result of their immunosuppressive effects. After a decade of employing the molecular diagnosis of those viruses, which replaced conventional virus isolation, we present the development of a real-time multiplex PCR for the simultaneous detection of both viruses. The real-time PCRs for MDV and for CAV alone are more sensitive than the respective end-point PCRs. In addition, the multiplex real-time shows a similar sensitivity when compared to the single real-time PCR for each virus. The newly developed real-time multiplex PCR is of importance in terms of the diagnosis and detection of low copies of each virus, MDV and CAV in single- and in multiple-virus infections, and its applicability will be further evaluated.

  18. ISOLDE PH team, from left to right: Jennifer Weterings (user support), Susanne Kreim (research fellow), Marek Pfützner (scientific associate), Maria Garcia Borge (team leader), Elisa Rapisarda (research fellow) , Magdalena Kowalska (physics coordinator), Jan Kurcewicz (applied fellow), Monika Stachura (applied fellow). Not in the photo: Kara Lynch (PhD student).

    CERN Multimedia

    Visual Media Office

    2013-01-01

    ISOLDE PH team, from left to right: Jennifer Weterings (user support), Susanne Kreim (research fellow), Marek Pfützner (scientific associate), Maria Garcia Borge (team leader), Elisa Rapisarda (research fellow) , Magdalena Kowalska (physics coordinator), Jan Kurcewicz (applied fellow), Monika Stachura (applied fellow). Not in the photo: Kara Lynch (PhD student).

  19. A discussion of a book: Historiografia prasy polskiej (do 1918 roku. Naukometryczna analiza dyscypliny 1945–2009 by Władysław Marek Kolasa. Kraków: Wydawnictwo Naukowe Uniwersytetu Pedagogicznego, 2013; “Prace Monograficzne” 678, ISBN 0239-6025, 978-83-7271-843-1, 525 pp. + BIbliography (CD (in Polish

    Directory of Open Access Journals (Sweden)

    Michał Kokowski

    2016-11-01

    Full Text Available This article presents a peer review of the book by Władysław Marek Kolasa on the historiography of the Polish press. It regards the methodology of historiography, the science of science and its sub-disciplines: scientometrics and bibliometrics.

  20. Characterizing the histopathology of natural co-infection with Marek's disease virus and subgroup J avian leucosis virus in egg-laying hens.

    Science.gov (United States)

    Wen, Yawen; Huang, Qi; Yang, Chengcheng; Pan, Ling; Wang, Guijun; Qi, Kezong; Liu, Hongmei

    2018-02-01

    Marek's disease virus (MDV) and avian leucosis virus (ALV) are known to cause tumours in egg-laying hens. Here, we investigated the aetiology of tumours in a flock of egg-laying hens vaccinated against MDV. We carried out gross pathology and histopathological examinations of the diseased tissues, identified virus antigen and sequenced viral oncogenes to elucidate the cause of death in 21-22-week-old hens. At necropsy, diseased hens had distinctly swollen livers, spleens, and proventriculus, and white tumour nodules in the liver. The spleen and liver had been infiltrated by lymphoid tumour cells, while the proventriculus had been infiltrated by both lymphoid tumour cells and myeloblastic cells. Subtype J ALV (ALV-J) and MDV were widely distributed in the proventricular gland cells, and the lymphoid tumour cells in the liver and the spleen. In addition, positive ALV-J signals were also observed in parts of the reticular cells in the spleen. MDV and ALV-J antigens were observed in the same foci of the proventricular gland cells; however, the two antigens were not observed in the same foci from the spleen and liver. The amino acid sequence of the AN-1 (the representative liver tumour tissue that was positive for both ALV-J and MDV) Meq protein was highly similar to the very virulent MDV QD2014 from China. Compared to the ALV-J HPRS-103 reference strain, 10 amino acids (224-CTTEWNYYAY-233) were deleted from the gp85 protein of AN-1. We concluded that concurrent infection with MDV and ALV-J contributed to the tumorigenicity observed in the flock.

  1. Postuumne Bourdieu : Bourdieu / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2005-01-01

    Ka 2003. a. ilmunud Pierre Bourdieu' (1930-2002) fotoalbumist "Alžeeria pildid" (Images d'Algerie: Une affinite elective), kuhu on P. Bourdieu poolt 1958-1961 Alžeerias jäädvustatud mustvalgetest fotodest valitud ligemale 150. 2003. a. korraldati P. Bourdieu fotode põhjal Araabia Maailma Instituudis Pariisis näitus

  2. Kuidas portreteerida koolkonda? / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2017-01-01

    Arvustus: Theoretical schools and circles in the twentieth-century humanities : literary theory, history, philosophy / edited by Marina Grishakova and Silvi Salupere. New York ; London : Routledge, 2015. (Routledge interdisciplinary perspectives on literature ; 42)

  3. Rõivakaubanduse edu saladused / Marek Maido

    Index Scriptorium Estoniae

    Maido, Marek

    2014-01-01

    H & M, Zara, Mango ja Uniqlol rõhutavad majandustarkvara ERP lahenduste olulist rolli ning kasutavad neid klientide eelistuste kaardistamiseks, varude kiireks täiendamiseks ning tarneketi juhtimiseks

  4. Replication kinetics and shedding of very virulent Marek's disease virus and vaccinal Rispens/CVI988 virus during single and mixed infections varying in order and interval between infections.

    Science.gov (United States)

    Islam, Tanzila; Walkden-Brown, Stephen W; Renz, Katrin G; Islam, A F M Fakhrul; Ralapanawe, Sithara

    2014-10-10

    Vaccination is thought to contribute to an evolution in virulence of the Marek's disease virus (MDV) as vaccines prevent disease but not infection. We investigated the effects of co-infections at various intervals between Rispens/CVI988 vaccine virus (Rispens) and very virulent MDV (vvMDV) on the replication and shedding of each virus. The experiment used 600 ISA Brown layer chickens in 24 isolators with all treatments replicated in two isolators. Chickens were vaccinated with Rispens and/or challenged with the vvMDV isolate 02LAR on days 0, 5, or 10 post hatching providing vaccination to challenge intervals (VCI) of -10, -5, 0, 5 or 10 days with the negative values indicating challenge prior to vaccination. Peripheral blood lymphocytes (PBL), feathers and isolator exhaust dust were sampled between 7 and 56 days post infection (dpi) and subjected to quantitative real-time polymerase chain reaction (qPCR) to differentiate the two viruses. Overall Rispens significantly reduced the viral load of vvMDV in PBL and feather cells and shedding in dust. Similarly vvMDV significantly reduced the viral load of Rispens in PBL and feather cells but not in dust. VCI significantly influenced these relationships having strong positive and negative associations with load of vvMDV and Rispens respectively. Differences between the two viruses and their effects on each other were greatest in PBL and feathers, and least in dust. This study expands our understanding of the interaction between pathogenic and vaccinal viruses following vaccination with imperfect vaccines and has implications for selection of appropriate samples to test for vaccination success. Copyright © 2014 Elsevier B.V. All rights reserved.

  5. Demokraatia diversiteet = Raznoobrazije form demokratii / Marek Strandberg

    Index Scriptorium Estoniae

    Strandberg, Marek, 1965-

    2008-01-01

    Šveitsi otsedemokraatia süsteemist ja selle rakendamisest Eestis esindusdemokraatliku võimu kõrval. Diagramm: Šveitsi rahvaalgatuslike ja kohustuslike referendumite tulemused 1848-2005. Ajaleht Poljana nr. 4

  6. Riigisektoris tulevad ümberkorraldused / Marek Helm

    Index Scriptorium Estoniae

    Helm, Marek, 1973-

    2009-01-01

    Rahandusministeeriumi projektijuht kirjutab riigile vajaliku ühtse teeninduskeskuse loomisest, mis suudaks tagada riigiasutustele ühtlaselt kvaliteetset raamatupidamise, personaliarvestuse ja hangete korraldamise teenust

  7. Elektrienergia hajutatud tootmine Eestis / Marek Muiste

    Index Scriptorium Estoniae

    Muiste, Marek, 1979-

    2006-01-01

    Eestis on välja kujunemas uus energeetiline struktuur, mida iseloomustab ühe suure tootmisüksuse kõrval tegutsevate lokaalsete väikese võimsusega elektrijaamade võrgustik. Lokaaljaamu iseloomustab taastuvate kütuste kasutamine ja seotus regiooni üldise arenguga. Tabelid, diagrammid

  8. Propagandistlik tellimustöö? / Marek Kallin

    Index Scriptorium Estoniae

    Kallin, Marek

    2007-01-01

    Rets. rmt.: Jeremy Rifkin. Euroopa unistus. OÜ Hermes, 2007. Artikli autor väljendab üllatust, et president Toomas Hendrik Ilves pidas vajalikuks osaleda intellektuaalselt nii pinnapealse teose esitlusel

  9. Semiootikud elavad edasi. Ka Tartus / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2000-01-01

    Arvustus: Sign System Studies. Vol. 26. Tartu : Tartu Ülikooli Kirjastus, 1998 ; Sign System Studies. Vol. 27. Tartu : Tartu Ülikooli Kirjastus, 1999 ; Kultuurisemiootika teesid / V. Ivanov, J. Lotman, A. Pjatigorski... jt. Tartu : Tartu Ülikooli Kirjastus, 1998. (Tartu Semiotics Library ; 1). Tekst vene, inglise ja eesti k. ; Tartu-Moskva semiootikakoolkonna mõistesõnastik / toim. Jan Levtshenko. Tartu : Tartu Ülikooli Kirjastus, 1999 (Tartu Semiotics Library ; 2). Tekst vene k. Osa teksti eesti ja inglise k

  10. Orienteerumiskaart vs. LiDAR / Marek Karm

    Index Scriptorium Estoniae

    Karm, Marek

    2012-01-01

    Bakalaureusetööst, mille eesmärk oli võrrelda orienteerumiskaardi reljeefi LiDAR-i andmete põhjal saadava reljeefimudeliga ning leida vastus küsimusele, kas o-kaart võib olla kasulik kooste- või kontrollmaterjal mistahes reljeefimudelile

  11. Kuidas õigustada esteetilist hoiakut? / Marek Volt

    Index Scriptorium Estoniae

    Volt, Marek, 1973-

    2011-01-01

    Eristatakse hoiakute-vahelist ja hoiaku-sisest õigustamist ning analüüsitakse esteetilise hoiaku episteemilist, sotsiaal-bioloogilist, moraalset, kunstilist, esteetilist ja hedoonilist õigustamist hoiaku-siseses kontekstis

  12. Marek Strandberg : rohelised on muutuse Eesti poliitikas juba saavutanud / Marek Strandberg ; interv. Ingvar Bärenklau

    Index Scriptorium Estoniae

    Strandberg, Marek, 1965-

    2007-01-01

    Roheliste erakonna esinumber, erakonna esimees vastab küsimustele erakonna rajamise, valimiskampaania, partei rahastamise ja programmi, põlevkivi kaevandamise, rahvusprobleemi, energiavaldkonna, kasiinode, rohelise mõtteviisi ja valitsuse moodustamise kohta. Vt. samas: Noppeid roheliste programmist; 3 küsimust

  13. Eesti vajab terasemat valitsust / tõlk. Marek Laane

    Index Scriptorium Estoniae

    2007-01-01

    Briti mõjukas majandusajakiri Economist kirjutas oma veebiväljaandes Eesti edust 1990. aastatel. Kuid parlamendivalimised näitasid, et Eestis nagu teistes endistes kommunistlikes maades puudub reformialdis valitsus. Kiitust pälvib Eesti president Toomas Hendrik Ilves, kes pani veto pronkssõduri seadusele ja taunis Eesti iseseisvuspäeva pidustustel peetud kõnes korruptsiooni, enesega rahulolu ja takerdunud reforme. Kommenteerivad Eesti Konjunktuuriinstituudi juhtiv teadur Leev Kuum, SEB Ühispanga analüütik Hardo Pajula, majandusministri nõunik Heido Vitsur ja peaministri nõunik Taavi Rõivas

  14. Turvalisus - meie kõigi õigus ja kohustus / Marek Helm

    Index Scriptorium Estoniae

    Helm, Marek, 1973-

    2007-01-01

    Siseministeeriumis on alustatud siseturvalisuse arengukava koostamist, mis tähendab, et uus valitsus tahab oma koalitsioonilepingus kriminaalpoliitika arengusuundadele lisaks heaks kiita Eesti turvalisuspoliitika arengusuunad aastani 2015

  15. Euroopa unelm / Jeremy Rifkin ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Rifkin, Jeremy

    2006-01-01

    Autori hinnangul võiksid ameeriklased eurooplastelt õppida solidaarsust, kaasatust, elukvaliteeti, jätkusuutlikku arengut ja rahu, eurooplased aga ameeriklastelt isiklikku vastutamist, lootusetunnet, optimismi ning riskimist. Vt. samas lk. 34-37 Linnar Viigi ja Jeremy Rifkini diskussiooni

  16. Kunsti hindamise ontoloogilised ja episteemilised eeldused / Marek Volt

    Index Scriptorium Estoniae

    Volt, Marek

    2006-01-01

    VKT - kunstiteose vahetu kogemuse teesi paikapidavusest. Mentalistlikud monismid. Dualistlikud ontoloogiad. Strawsoni ajalooline dualism. Surrogaadiargumendid. Personalism ja verbaalsed surrogaadid. Kirjandus lk. 67-71

  17. Pariisi kiri. Kevadine raamatuhooaeg : [1999. a.] / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    1999-01-01

    Ka Pariisi rahvusvahelisest raamatumessist. Rets. rmt.: Genette, Gérard. Figures IV. S. l. : Seuil, 1999; Eribon, Didier. Arutlused gay-küsimusest. Pariis : Fayard, 1999. Eco, Umberto. Kant ja nokkloom. Pariis : Grasset, 1999 (prantsuse keeles, originaal itaalia k.: Milaano: Bompiani, 1997)

  18. Towards modern STI policy-making in Estonia / Marek Tiits

    Index Scriptorium Estoniae

    Tiits, Marek

    2003-01-01

    Autor arutleb rahvusliku tehnoloogia-, innovatsiooni- ja teaduspoliitika vajalikkuse üle ning leiab, et Eesti majanduslik areng peaks tulevikus põhinema eelkõige hariduse, teaduse ja innovatsiooni kvaliteedi tõstmisel

  19. Rämpsu ja sodi evangeelium / Marek Strandberg

    Index Scriptorium Estoniae

    Strandberg, Marek, 1965-

    2008-01-01

    Autori arvates vajaks me omavalitsuste korraldatud kulupõhist jäätmekäitlusmehhanismi, kus kodanikele ei panda muid lepingulisi ja rahalisi kohustusi, kui nad on oma jäätmed kokkulepitult sorteerinud

  20. Putin lubas tshetsheenidele suurt autonoomiat / Kristiina Ojuland ; interv. Marek Laane

    Index Scriptorium Estoniae

    Ojuland, Kristiina, 1966-

    2000-01-01

    ENi delegatsiooni koosseisus Moskvas ja Tšetšeenias viibinud K. Ojuland selgitab Vene presidendi nägemust võimalikust suuremast autonoomiast tshetsheenidele. Autor: Reformierakond. Parlamendisaadik. Ilmunud ka: Põhjarannik 21. jaan. lk. 2

  1. Carlo Ginzburg: anomaalia viitab normile / intervjueerinud Marek Tamm

    Index Scriptorium Estoniae

    Ginzburg, Carlo, 1939-

    2014-01-01

    Intervjuu itaalia ajaloolase Carlo Ginzburgiga tema raamatu "Ükski saar pole saar : neli pilguheitu inglise kirjandusele globaalsest vaatenurgast" eesti keeles ilmumise puhul. Teos ilmus Tallinna Ülikooli Kirjastuses

  2. Aasta pärast terrorit / Marek Laane

    Index Scriptorium Estoniae

    Laane, Marek, 1969-

    2002-01-01

    Autor analüüsib Iraani ajaloolaste Ladani ja Roya Bornmandi artiklis "Terror, islam ja demokraatia", Samuel Huntingtoni teoses "Tsivilisatsioonide kokkupõrge", Bobitti raamatus "Shield of Achilles. War, Peace and the Cource of History" esitatud seisukohti. Pärast septembriterrorit on analüütikute hinnangul radikalismi osa islamiilmas kahanenud

  3. Millal jõudsid dominikaanid Tallinna / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2001-01-01

    Dominiiklaste ajalugu, Tallinnasse jõudmine ja lahkumine Simon Tugwelli "Historia" tõlgenduste järgi. Lisa: Historia Ordinis Praedicatorum in Dania. Eludaatumid: Dominicus, Püha, 1170-1221 ; Guillelmus, Modenast, 1184-1251

  4. Kuidas kirjutatakse ajalugu? / Roger Chartier ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Chartier, Roger

    2007-01-01

    Kirjanduslikest tekstidest sotsiaalajaloo uurimisallikana, juhuse ja paratamatuse vahekorrast ajaloos ja Prantsuse revolutsiooni käsitlusest Pariisi õppe- ja teaduskeskuse Ecole des Hautes Etudes en Sciences Sociales professori R. Chartier'i teostes. Varem ilm.: Tekstid, praktikad ja lugejad : intervjuu Roger Chartier'ga // Chartier, Roger. Prantsuse revolutsiooni kultuurilised lätted. - Tallinn, 2002. - Lk. 274-290

  5. Värviline hobi seaduse piirimail / Marek Mühlberg

    Index Scriptorium Estoniae

    Mühlberg, Marek

    2007-01-01

    Tartu kõrgema kunstikooli rektor Vallo Nuust grafiti ühiskonnakriitilisest olemusest, sellega seonduvatest probleemidest, Kristjan Bachmann ja Ivari Lipp grafitientusiastidena grafiti õppimis- ja õpetamisvõimalustest. Grafitite tegemine valesse kohta võib olla varavastane süütegu, mille eest tuleb karistust kanda. Kommenteerib Lõuna politseiprefektuuri korrakaitseosakonna preventsioonitalituse komissar Marina Paddar

  6. Outbreaks of Marek's Disease in Layer Chickens Farms in Khartoum ...

    African Journals Online (AJOL)

    ... that infection of MD in vaccinated adult commercial type chickens might be due to de novo infection (Super infection) with highly virulent strains despite existing considerable levels of vaccine immunity and age resistance, also vaccination failure may perhaps considered one of the important causes of disease outbreaks.

  7. Kuidas kirjutatakse ajalugu? / Tzvetan Todorov ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Todorov, Tzvetan

    2007-01-01

    Bulgaaria päritolu prantsuse kirjandusuurija ja ideeajaloolase erialasest tegevusest ja loomingust. Varem ilm.: Tähendus, tõde ja dialoog : intervjuu Tzvetan Todoroviga // Todorov, Tzvetan. Ameerika vallutamine : teise probleem. - Tallinn, 2001. - Lk. 325-338

  8. Pudemed möödunud aegade kroonikast / Marek Laane

    Index Scriptorium Estoniae

    Laane, Marek, 1969-

    2002-01-01

    Esimene Peter Jacksoni käe all valmivast kolmest filmist J.R.R. Tolkieni triloogia "Sõrmuste isand" alusel - "Sõrmuse vennaskond", "The Lord of the Rings : The Fellowship of the Ring" : Uus-Meremaa, Ameerika Ühendriigid 2001

  9. Sokali afäär : 'postmodernismi' kriitikat / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    1997-01-01

    Kaasaegsete kultuuriteooriate kriitikast, eriti Alan D. Sokali paroodiast 'Piiride rikkudes: kvantgravitatsiooni hermeneutilise transformatsiooni poole' (Social Text 1996 (kevad-suvi), nr. 46/47) ning A. D. Sokali ja Jean Bricmont'i pamfletist 'Intellektuaalsed pettused' (Paris, 1997)

  10. Kuidas kirjutatakse ajalugu? / Alain Corbin ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Corbin, Alain

    2007-01-01

    Pariis I Ülikooli emeriitprofessori A. Corbini teoste temaatikast ja uurimistöödest. Varem ilm.: Emotsioonid, tunded ja kired : intervjuu Alain Corbiniga // Corbin, Alain. Kannibalide küla : hirm ja raev 19. sajandi Prantsusmaal. - Tallinn, 2000. - Lk. 187-195

  11. Kuidas kirjutatakse ajalugu? / Jacques Le Goff ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Le Goff, Jacques

    2007-01-01

    Prantsuse ajaloolase ja ajakirja Annales ühe peatoimetaja J. Le Goff'i teostest. Varem. ilm.: Ajalugu, antropoloogia ja imaginaarsus : intervjuu Jaques Le Goffiga // Le Goff, Jacques. Raha või elu : majandus ja religioon keskajal. - Tallinn, 2001. - Lk. 108-126

  12. McCain, Lieberman ja meie / Marek Strandberg, Indrek Tarand

    Index Scriptorium Estoniae

    Strandberg, Marek, 1965-

    2005-01-01

    USA senaatorite, vabariiklase John McCaini ja demokraat Joe Liebermani poolt USA senati menetlusse antud kahest seaduseelnõust, millest esimene kohustab USA presidenti astuma samme Venemaa ajutiseks väljaheitmiseks rikaste riikide ühendusest G7 ja teine on tuntud kui Climate Stewardship Act ehk kliimahoole seaduseelnõu. Artikli autorid Ilmahoole algatusrühmast kutsuvad üles toetama McCaini-Liebermani initsiatiivi, mis kaitseb ka Eesti välispoliitika huve

  13. Hulluse tõde mõistuse ajastul / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2004-01-01

    Rets. rmt.: Foucault, Michel. Hullus ja arutus. Hullumeelsuse ajalugu klassikalisel ajastul. Tartu, 2003 ; Foucault, Michel. Le pouvoir psychiatrique. Cours au College de France, 1973-1974. Pariis, 2003. Samal teemal : Vahing, Vaino. Ühiskond ja vaimuhaigus, lk. B10

  14. Kolm Goncourt'i laureaati korraga / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2002-01-01

    Arvustus: Tournier, Michel. Haldjakuningas / tlk. Laine Hone. Tallinn : Eesti Raamat, 2002 ; Rouaud, Jean. Auväljad / tlk. Vladimir Indrikson. Tallinn : Atlantis, 2002 ; Roze, Pascale. Hävituslendur Zéro / tlk. Kaja Riesen. Tallinn : Olion, 2002

  15. Kuidas kirjutatakse ajalugu? / Jacques Revel ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Revel, Jacques

    2007-01-01

    Prantsuse ajaloolase ja ajakirja Annales ühe peatoimetaja J. Revel'i erialasest tegevusest ja teostest. Varem. ilm.: Sündmused, jutustus ja analüüsiskaalad : intervjuu Jacques Reveliga // Revel, Jacques, Farge, Arlette. Mässu loogika : lasteröövlite afäär Pariisis 1750. - Tallinn, 2005. - Lk. 109-123

  16. Kuidas lugeda "Meeste domineerimist"? / Patrick Champagne ; tlk. Marek Tamm

    Index Scriptorium Estoniae

    Champagne, Patrick

    2005-01-01

    Rets. rmt.: Bourdieu, Pierre. Meeste domineerimine. Tallinn, 2005. Kommenteerivad (lk. 12-14) Liina Lukas, Rein Ruutsoo (TLÜ õppejõud), Marina Grišakova, Aare Pilv, Airi-Alina Allaste, Raivo Vetik (TLÜ Õppejõud), Andres Härm, Voldemar Tomusk

  17. "800 aastat" - millest ja milleks? / Linda Kaljundi, Marek Tamm

    Index Scriptorium Estoniae

    Kaljundi, Linda, 1979-

    2008-01-01

    Tallinna Ülikooli keskaja keskuse ja Põhjamaade keskajauuringute keskuse koostöös Tallinnas 22.-24. maini korraldatavast konverentsist "The Chronicle of Henry of Livonia : Crusading and Chronicle Writing at the Medieval Baltic Frontier"

  18. Kuidas kirjutatakse ajalugu? / Natalie Zemon Davis ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Davis, Natalie Zemon

    2007-01-01

    Ülevaade Princentoni Ülikooli emeriitprofessori ja Ameerika Ajalooühingu endise presidendi N. Z. Davis'e teostest. Varem ilm.: Ajalugu, filmikunst ja heidikud : intervjuu Natalie Zemon Davisega // Davis, Natalie Zemon. Martin Guerre'i tagasitulek. - Tallinn, 2002. - Lk. 162-177

  19. Inimnäoline ajalugu : medievist Marek Tamm tutvustab eesti keelde jõudnud inimesekeskseid mikroajalookäsitlusi / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2001-01-01

    Arvustus: Ginzburg, Carlo. Juust ja vaglad : ühe 16. sajandi möldri maailm /tlk. Viivika Atkin. Tln. : Varrak, 2000; Barokiajastu inimene / koost. Rosario Villari; tlk. Heete Sahkal, Heigo Sooman, Piret Peiker. Tln. : Avita, 2000

  20. Mitte rohkem kontrolli, vaid maksuanalüüs / Marek Helm

    Index Scriptorium Estoniae

    Helm, Marek, 1973-

    2005-01-01

    Maksedistsipliini parandamise eesmärgil liigub maksuhaldur seni valitsenud maksu järelkontrolli praktikalt järk-järgult ennetavate tegevusmeetodite rakendamisele ja otsib kahe meetodi vahel tasakaalu

  1. Eesti võimekusest ulatuslike metsapõlengute kustutamisel / Marek Helm

    Index Scriptorium Estoniae

    Helm, Marek, 1973-

    2006-01-01

    Ilmunud ka: Severnoje Poberezhje 19. juuli lk. 2. Siseministeeriumi sisejulgeolekupoliitika osakonna juhataja sõnul on ministeerium seadnud endale eesmärgiks parandada riskianalüüside kvaliteeti ja ohuhinnangute andmist. Sisejulgeoleku süsteemi on vaja kaasata sisulisemalt ka teised ministeeriumid, aga ka maavalitsused

  2. Baltimaad - kas "uue" Euroopa esmaasukad? / Jeroen Bult ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Bult, Jeroen

    2005-01-01

    Ajakirjanikud, teadlased ja rahvusvaheliste suhete analüütikud kasutavad "vana" ja "uue" Euroopa metafoori oma arutlustes Atlandi üleste pingete, Euroopa Liidu praeguse halvatuse ning sotsiaalmajanduslike probleemide üle, millega seisavad silmitsi EL-i suuremad liikmesriigid. See jaotus on omamoodi aluseks ka raamatule "The Baltic States And Their Region. New Europe Or Old? ". Raamatu aluseks on 2004. a. Glasgow's peetud samanimeline konverents

  3. Eesti-Vene kompleks / Jeroen Bult ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Bult, Jeroen, 1971-

    2007-01-01

    Rahvusvaheliste sotsiaaluuringute analüütik kirjutab Eesti keeldumisest anda luba Nord Streamile uuringute tegemiseks Eesti majandustsoonis, Eesti, Vene ja Saksa suhetest ja leiab, et uuringuloa andmisega merepõhja uuringuteks oleks Eesti saanud tihendada sidemeid EL-i suurima riigi Saksamaaga

  4. Euroopa halvavad ja ohtlikud ummikteed / Jeroen Bult ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Bult, Jeroen

    2005-01-01

    Prantsusmaa ja Hollandi negatiivsed hääletustulemused Euroopa Liidu põhiseadusliku leppe osas ja 2007-2013. aasta eelarvevaidlused on viinud Euroopa Liidu sügavasse kriisi, mille tagajärjel ei suudeta tõenäoliselt välja töötada ega kasutusele võtta ühist välis- ja kaitsepoliitikat. Seetõttu võib Euroopa Liidust võib kujuneda pelk vabakaubandustsoon

  5. Venemaa otsib lahendust konfliktile Tšetšeeniaga / Marek Laane

    Index Scriptorium Estoniae

    Laane, Marek, 1969-

    1998-01-01

    Tšetšeenia presidendi A. Mashadovi ja Venemaa peaministri S. Kirijenko kohtumisest 1. aug., kus S. Kirijenko lubas Tšetšeenial aidata taastada naftatööstust ning taotleda piirkonnale erimajandustsooni staatust

  6. Mida teha tumeda minevikuga? / Bruno Groppo ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Groppo, Bruno

    2005-01-01

    Autor keskendub küsimusele, kuidas trauma üle elanud ühiskond peaks oma minevikust üle saama, kui tingimused riigis normaliseeruvad, ning käsitleb lähemalt sellega seonduvalt olukorda Argentinas, Tšiilis, Venemaal

  7. Auahnus ja mitmemõttelisus / Tiago Marques ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Marques, Tiago

    2007-01-01

    Autor vaatleb arenguid, mida võib Euroopa Liidule tuua Portugal eesistujamaana ja leiab, et koos uue Euroopa Liidu lepingu eeldatava heakskiitmisega esitab Portugali programmile suurima väljakutse Euroopa Liidu ja Aafrika tippkohtumine

  8. Jaapan nõuab Ühendriikidelt hukkunud laeva ülestõstmist / Marek Laane

    Index Scriptorium Estoniae

    Laane, Marek, 1969-

    2001-01-01

    Hawaii lähistel õppustel kiiret pinnaletõusu harjutanud USA allveelaev Greeneville põrkas kokku Jaapani õppelaevaga Ehime Maru, õnnetuse tagajärjel hukkus tõenäoliselt 9 jaapanlast. Skeem: USA allveelaev uputas Jaapani laeva

  9. Abraham Lincolni nähtamatud käed / Marek Tiits

    Index Scriptorium Estoniae

    Tiits, Marek

    2005-01-01

    Eesti probleem pole mitte inimeste vähene ettevõtlikkus, arvab autor, vaid majanduskeskkond, mis soosib pigem tarbimist kui ekspordile orienteeritud tegevuste arendamist. Eesti vajab Ameerika ühendamise aegset poliitikat, mille keskmes oli sotsiaalne mobiilsus ning majanduse struktuuri ajakohastamine

  10. Islam ja sõnavabadus - Euroopa lõhestajad / Jeroen Bult ; tõlkinud Marek Laane

    Index Scriptorium Estoniae

    Bult, Jeroen, 1971-

    2008-01-01

    Autor võrdleb Taani karikatuuriskandaali tagajärgi Hollandis valminud islamiteemalise filmi "Fitna" põhjustatud pahameelega ja leiab, et mitte kõik Euroopa poliitikud ei ole veendunud sõnavabaduse kaitsmise vajaduses

  11. 76 FR 12932 - Availability of an Environmental Assessment for Field Testing Fowl Laryngotracheitis-Marek's...

    Science.gov (United States)

    2011-03-09

    ... Inspection Service (APHIS), as well as obtain APHIS' authorization to ship the product for field testing. To... Inspection Service [Docket No. APHIS-2011-0011] Availability of an Environmental Assessment for Field Testing... and Plant Health Inspection Service, USDA. ACTION: Notice. SUMMARY: We are advising the public that...

  12. Differential serotonergic mediation of aggression in roosters selected for resistance and susceptibility to Marek's disease

    Science.gov (United States)

    Serotonin (5-HT) is a primary regulating neurotransmitter involved in aggressive and impulsive behaviors in mammals. Previous studies have also demonstrated the function of serotonergic system in regulating aggression is affected by both genetic and environmental factors. The serotonergic system m...

  13. Marek Zvelebil (1952-2011) a zemědělská hranice

    Czech Academy of Sciences Publication Activity Database

    Končelová, Markéta; Květina, Petr

    2011-01-01

    Roč. 63, č. 4 (2011), s. 703-707 ISSN 0323-1267 R&D Projects: GA ČR(CZ) GAP405/11/1590 Institutional research plan: CEZ:AV0Z80020508 Keywords : neolithisation * identity * hunter-gatherers Subject RIV: AC - Archeology, Anthropology, Ethnology

  14. Kas sotsiaalmeedias turundamiseks tehtud investeeringu tootlust saab mõõta? Donna L. Hoffman, Marek Fodor

    Index Scriptorium Estoniae

    Hoffmann, Donna L.

    2010-01-01

    Sotsiaalmeedia vahendusel toimuva turunduse efektiivsuse mõõtmise võimalustest. Lisatud tabel : Sotsiaalmeediarakenduste olulisemad mõõdikud, süstematiseerituna võtmetähtsusega sotsiaalmeedia eesmärkide järgi

  15. Kas terrorismi saab neutraalselt defineerida? = Is it possible to define terrorism neutrally? / Marek Järvik

    Index Scriptorium Estoniae

    Järvik, Marek

    2006-01-01

    Terrorismi definitsioon, vägivald, poliitilised eesmärgid, terrorism ja kuritegevus, avalikkus, revolutsioon ja vabadusvõitlus. Ettekanne Kaasaegse Kunsti Eesti Keskuse 4. ettekannete päeval "Kunstnike moraalsed valikud kultuurikonfliktides" Tallinna Kunstihoones 27.04.2006. Bibliograafia lk. 99

  16. Global Conflicts and the Macro-Regional Modernities: Interview with Marek Hrubec

    Czech Academy of Sciences Publication Activity Database

    Hrubec, Marek; Solík, M.

    2015-01-01

    Roč. 6, č. 1 (2015), s. 83-98 ISSN 1338-130X Institutional support: RVO:67985955 Keywords : global conflicts * injustice * recognition * macro-regions * modernities * critical theory * intercultural Subject RIV: AJ - Letters, Mass- media , Audiovision

  17. USA peab senist kurssi jätkama / Colin L. Powell ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Powell, Colin L.

    2003-01-01

    USA riigisekretär Colin Powell kinnitab, et Ameerika Ühendriikidel tuleb Iraagis ja Afganistanis jätkata demokratiseerimispoliitikat. Artikkel on kirjutataud Colin Powelli 10. nov. City College of New Yorkis peetud kõne põhjal

  18. Eesti kirjandus Prantsusmaal 2002 : jälle ebaharilikult priske saak / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2003-01-01

    2002. a. ilmus prantsuse keeles neli eesti kirjandusteost: Antoine Chalvini koostatud novellivalimik "Les hirondelles" ("Pääsukesed"); Eva Koffi näidend " Meie isa" ("Notre père", tõlkija Eva Toulouze); Jaan Kaplinski tõlkekogu "Le désir de la poussière" ("Tolmu igatsus", koostaja ja tõlkija Antoine Chalvin); Karl Ristikivi "Inimese teekond" ("Chemin terrestre", tõlkija Tarah Montbélialtz, pseud.)

  19. Surra Tallinna eest / Patrick J. Buchanan ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Buchanan, Patrick J.

    2007-01-01

    USA presidendikandidaat kirjutab Venemaa-Eesti konfliktist pronkssõduri pärast ja võimalikust Venemaa rünnakust Eesti vastu ning arvab, et USA ei peaks, hoolimata NATO põhimõttest, sekkuma, sest see tooks kaasa veel suurema sõja

  20. Pariisi kiri. Suvine raamatuhooaeg = A letter from Paris. Summer book season / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2010-01-01

    Prantsusmaal 1999. aasta suvel ilmunud raamatutest. Ka Ülemaailmsest Kultuuride Akadeemiast (Académie universelle des cultures) ja selle organisatsiooni korraldatud konverentsist "Mälu ja ajalugu" (Pariis, 1998)

  1. Teekond Kirjasõna Vabariigis / Märt Väljataga ; intervjueerinud Marek Tamm

    Index Scriptorium Estoniae

    Väljataga, Märt, 1965-

    2015-01-01

    Märt Väljataga tõlgitud R. Rorty artiklist "Pragmatism ja filosoofia", mis ilmus Akadeemia 1992, nr. 2, lk. 281-282, 285, tema filosoofiast ja Märt Väljataga tööst ajakirja "Vikerkaar" toimetajana ning tõlkijana

  2. Energiasõltumatuse ohtlik fantaasia / A. F. Alhajji, Gavin Longmuir ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Alhajji, A. F.

    2007-01-01

    Autorid leiavad, et maailmas üha häälekamalt kõlav soov taotleda energiasõltumatust on absurdne, sest selle poole püüdlevate maade energeetiline julgeolek tegelikult väheneb. Kommenteerib energeetikaekspert Raivo Vare

  3. Postcolonial heterotopias in Marek Piestrak's Estonian co-productions : a paracinematic reading / Eva Näripea

    Index Scriptorium Estoniae

    Näripea, Eva, 1980-

    2014-01-01

    M.Piestraki populaarsete ja "parafilmidena" käsitletavate "Navigaator Prix"(1978) ja "Madude oru needus"(1988) analüüs. Piestraki filmide ruumimaailmu uurides toetutakse Foucault' heterotoopiakontseptsioonile ja mõningatele postkolonialistku teooria mõttekäikudele

  4. Iisraeli valimistel pistavad täna rinda rahukotkas ja rahutuvi / Marek Laane

    Index Scriptorium Estoniae

    Laane, Marek, 1969-

    2003-01-01

    Iisraeli parlamendivalimistel selgub, kas rahvas eelistab paremtsentristliku peaministri Ariel Sharoni poliitika jätkumist või tööparteilasi. Tabel: Ariel Sharon. Diagramm: Viimased arvamusküsitlused

  5. Kirjandusteooria ja ajalookirjutis / Hayden White ; tõlk. Erkki Sivonen, toim. Marek Tamm

    Index Scriptorium Estoniae

    White, Hayden

    2003-01-01

    Moodsa kirjandusteooria tähtsusest ajaloo, ajalooteadvuse, ajaloodiskursuse ja ajalookirjutuste teoorias. Tõlke allikas: White, H. Figural Realism. Studies in the Mimesis Effect. Baltimore, London : The John Hopkins University Press : 1999

  6. Kirjandusteooria ja ajalookirjutis / Hayden White ; tõlk. Erkki Sivonen, toim. Marek Tamm

    Index Scriptorium Estoniae

    White, Hayden

    2003-01-01

    Moodsa kirjandusteooria tähtsusest ajaloo, ajalooteadvuse, ajaloodiskursuse ja ajalookirjutuste teoorias. White, H. Figural realism : studies in the mimesis effect. Baltimore ; London : J. Hopkins University Press : 1999

  7. "Kurja lillede" kuus ärakeelatud luuletust / Charles Baudelaire ; saatesõna: Marek Tamm

    Index Scriptorium Estoniae

    Baudelaire, Charles

    2000-01-01

    Sisu: Kalliskivid / tlk. Ain Kaalep ; Lethe / tlk. Märt Väljataga ; Temale, kes on liiga rõõmus / tlk. Ain Kaalep ; Lesbos / tlk. Ilmar Laaban ; Äraneetud naised (Delphine ja Hyppolyte) / tlk. Ain Kaalep ; Vampiiri metamorfoosid / tlk. August Sang. Orig.: Les Bijoux ; Le Léthé ; A celle qui est trop gaie ; Lesbos ; Femmes damnées. Delphine et Hippolyte ; Les Métamorphoses du vampire

  8. Kujuteldavad maastikud : Ida-Baltikum ja 13. sajandi Euroopa kultuuriline geograafia / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2014-01-01

    Vajadusest tekstilise kaardistamise kaudu ühendada Eesti- ja Liivimaa läänekristlikus Euroopas käibiva geograafilise diskursusega ning selleks kasutatud retoorilistest ja narratiivsetest võtetest

  9. Tekst ja subjekt. Tartu koolkonna teine põlvkond / Marek Tamm

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    1997-01-01

    Arvustus: Lotman, Mihhail. Mandelshtam i Pasternak : popõtka kontrastivnoi poetiki. Tallinn : Aleksandra, 1996. (Biblioteka zhurnala Tallinn); Torop, Peeter. Dostojevski : istorija i ideologija. Tartu : Tartu Ülikooli Kirjastus, 1997

  10. Saudi rahuplaan ajas Iisraeli juhid tülli / Marek Laane

    Index Scriptorium Estoniae

    Laane, Marek, 1969-

    2002-01-01

    Saudi Araabia esitatud Lähis-Ida rahuplaan on ajanud Iisraeli juhtkonna tülli: peaminister Ariel Sharon on selle vastu, president Moshe Katsar on aga valmis saudidega kohtuma. Kaart: Iisraeli muutuvad piirid

  11. Sotsiaaldemokraatia taassünd Eestis / Tony Blair ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Blair, Tony, 1953-

    2004-01-01

    Ilmunud ka: Molodjozh Estonii, 9. veebr. 2004, lk. 3, lüh. Suurbritannia peaminister tervitab Mõõdukate kongressi ja sotsiaaldemokraatide taasärkamist ning kirjeldab parteide ja riikide koostöövõimalusi ühises Euroopas

  12. Teadmistepõhine Eesti 2010 : kontekst ja poliitikasoovitused / Marek Tiits, Rainer Kattel, Tarmo Kalvet

    Index Scriptorium Estoniae

    Tiits, Marek

    2004-01-01

    Autorite hinnangul on Eesti arengule suuna andmiseks vaja klastripõhist konkurentsivõime arendamise strateegiat, mis põhineks konkreetsete tehnoloogiate ja majandusklastrite pikemaajalistel strateegilistel arengukavadel. Diagramm

  13. Havipüügist hilissügisel jerklantidega / Pavel Margulis, Marek Sukk, Marko Zlatin

    Index Scriptorium Estoniae

    Margulis, Pavel

    2015-01-01

    Jerkimise kohta arvavad paljud kalastajad, et see on üks keeruline püügiviis, mida on raske õppida ning mis nõuab spetsiaalset ja kallist varustust. Oma kogemusi jagavad jergipüüdjad, kes on nende lantidega Eesti vetest muljetavaldavaid havisid välja tõmmanud

  14. Enhanced Catalogue Records Positively Impact Circulation but Are Not Used to Their Potential in Patron Searching. A Review of: Tosaka, Y., & Weng, C. (2011. Reexamining content-enriched access: Its effect on usage and discovery. College & Research Libraries, 72(5, 412-427.

    Directory of Open Access Journals (Sweden)

    Cari Merkley

    2012-09-01

    Full Text Available Objective – To determine how contentenrichedcatalogue records impact thecirculation rates of print resources in foursubject areas, and to investigate how thisadditional metadata influences OPACsearching and item retrieval.Design – Analysis of circulation data,bibliographic records, and OPAC search logs.Setting – A library at a four-yearundergraduate residential college in theNorth-eastern United States.Subjects – Bibliographic records for 88,538titles; data from 7,782 circulation transactions;and 130 OPAC search strings and relatedcirculation data.Methods – In the first part of the study,bibliographic records for print items publishedsince 1990 were extracted from the library’sintegrated library system (ILS in the followingLibrary of Congress (LC classes: D, E, F, H, J,L, P, Q, R, S, and T. It is assumed thatelectronic books were excluded from thisstudy because their usage is not tracked in theILS. These LC classes were chosen tocorrespond to the subject areas targeted by theresearchers for comparison – “history, socialsciences, language and literature, and scienceand technology” (p. 416. The data fileincluded the publication date of the title, aswell as values for the MARC fields identified by the researchers as containing content-enriched data. These fields were MARC 505 (an item’s table of contents or list of works included, MARC 520 (summaries or annotations, and MARC 856 (URL to electronic location of related material or electronic copy (p. 416; Library of Congress Network Development and MARC Standards Office, 2003, 2008a, 2008b. The authors analyzed records for 88,538 titles and determined the total number of records containing each of the MARC fields either singly or in combination.Data relating to circulation transactions for items located in these LC classes from January to May 2009 was also identified. Like the bibliographic records, circulation data was pulled for print items only. The researchers identified 7,782 circulation transactions that met the study criteria for the period in question.In the second part of the study, circulation data for September 22, 2009 was obtained and sorted into the four subject categories identified in Part I of the study. The authors indicate that this date was chosen at random, but do not specify how. Researchers compared the records of the 133 titles borrowed that day from the LC classes studied to the OPAC search logs from September 16-22, 2009 to determine which searches led to the circulation of these items. The authors felt that searches resulting in checkouts on the day in question may have begun earlier in the week. The searches that led to borrowing were recorded and categorized as keyword, title, author, or other searches. If a user entered a title or author name into the keyword field, these were classed as known item searches in the appropriate categories. The authors identified and analyzed 130 searches relating to circulated items.Main Results – In the first part of the study, the number of catalogue records that contained MARC 505, 520, and/or 856 fields significantly increased for titles published between 1990 and 2007, with a slight decrease in 2008. MARC 505 was the most common content-enriched field until 2000, after which the presence of MARC 856 grew significantly. The MARC 520 field was used least often, making it difficult to draw firm conclusions about its impact on circulation.The incidence of enhanced records was very low among older books in the study. Only 14.3% of items published between 1990 and 1994, and 19.3% of items published between 1995 and 1999, had records that contained MARC 505, 520, or 856 fields. In contrast, the percentage of enhanced records was very high (80.9% for items published between 2005 and 2008. The authors acknowledged that these stark imbalances created skewed comparison data for items published in these date ranges. As such, they suggested that the data for titles published between 2000 and 2004 offered the most balanced comparison because the numbers of enhanced and non-enhanced records were almost equal. The overall circulation of items with enhanced records published between 2000 and 2004 was 2.9% higher than for items with non-enhanced records, constituting a relative percentage difference of 30.7%. The relative percentage difference in this period was higher for books in science and technology (36.9%, followed by history (34%, language and literature (30.6%, and social sciences (25.7%. Enhanced records also had a positive impact on circulation for items published between 1990 and 2000 over their non-enhanced counterparts; however, this positive growth levelled off for items published between 2005 and 2008, with almost equal circulation rates between items with enhanced and non-enhanced records during this period. The impact of the three MARC fields was examined, and the presence of the MARC 505 field was most associated with increased circulation rates, in part because it was the most commonly used field of the three for the period in question. The number of records with MARC 520 and 856 fields was not sufficient to draw firm conclusions about their impact on circulation. While not the focus of the study, the circulation data also suggested a preference for current titles among all four subject areas, most significantly among the social sciences and science and technology. The second part of the study found that keyword searching was the most common strategy employed by patrons, with 49.6% of the 130 searches examined falling into this category. Keyword searches most commonly led to the borrowing of items from the history LC classes, while title searches were most common in science and technology. Known item searches (title or author accounted for 45.9% of the overall searches analyzed. However, in most cases, the search terms used that led to a title circulating were found in the title and subject fields, rather than in a content-enriched MARC field. The researchers suggested that this may be due to the appearance of search results in the OPAC (brief rather than full record and the way relevancy sorting was calculated, as contents notes were not given a high weighting in the OPAC’s formula.Conclusion – The study found that enhanced catalogue records led to higher circulation rates in the four subject areas studied. The increased proportion of content-enriched records in the overall catalogue in recent years suggested that their value had been recognized by the library. The limited role these enhanced fields played in the September 22, 2009 searches suggested that further work on improving how this information is displayed to users in the OPAC and sorted is needed. The researchers identified areas for future research including the role of the publication date and the impact of improvements to the display of content fields in the OPAC on the circulation of items with content-enriched records.

  15. Revision of the subfamily Opiinae (Hymenoptera, Braconidae from Hunan (China, including thirty-six new species and two new genera

    Directory of Open Access Journals (Sweden)

    Li Xi-Ying

    2013-02-01

    postpectalis sp. n. are described. All species are illustrated and keyed. In total 30 species of Opiinae are sequenced and the cladograms are presented. Neopius Gahan, 1917, Opiognathus Fischer, 1972, Opiostomus Fischer, 1972, and Rhogadopsis Brèthes, 1913, are treated as a valid genera based on molecular and morphological differences. Opius vittata Chen & Weng, 2005 (not Opius vittatus Ruschka, 1915, O. ambiguus Weng & Chen, 2005 (not Wesmael, 1835 and O. mitis Chen & Weng, 2005 (not Fischer, 1963 are primary homonyms and are renamed into Phaedrotoma depressa Li & van Achterberg, nom. n., Opius cheni Li & van Achterberg, nom. n. and O. wengi Li & van Achterberg, nom. n., respectively. Phaedrotoma terga (Chen & Weng, 2005 comb. n., Diachasmimorpha longicaudata (Ashmead, 1905 and Biosteres pavitita Chen & Weng, 2005, are reported new for Hunan, Opiostomus aureliae (Fischer, 1957 comb. n. is new for China and Hunan; Xynobius maculipennis (Enderlein, 1912 comb. n. is new for Hunan and continental China and Rhogadopsis longuria (Chen & Weng, 2005 comb. n. is new for Hunan. The following new combinations are given: Apodesmia puncta (Weng & Chen, 2005 comb. n., A. tracta (Weng & Chen, 2005 comb. n., Areotetes laevigatus (Weng & Chen, 2005 comb. n., Phaedrotoma dimidia (Chen & Weng, 2005 comb. n., P. improcera (Weng & Chen, 2005 comb. n., P. amputata (Weng & Chen, 2005 comb. n., P. larga (Weng & Chen, 2005 comb. n., P. osculas (Weng & Chen, 2005 comb. n., P. postuma (Chen & Weng, 2005 comb. n., P. rugulosa (Chen & Weng, 2005 comb. n., P. tabularis (Weng & Chen, 2005 comb. n., Rhogadopsis apii (Chen & Weng, 2005 comb. n., R. dimidia (Chen & Weng, 2005 comb. n., R. diutia (Chen & Weng, 2005 comb. n., R. longuria (Chen & Weng, 2005 comb. n., R. pratellae (Weng & Chen, 2005 comb. n., R. pratensis (Weng & Chen, 2005 comb. n., R. sculpta (Chen & Weng, 2005 comb. n., R. sulcifer (Fischer, 1975 comb. n., R. tabidula (Weng & Chen, 2005 comb. n., Xynobius complexus (Weng & Chen, 2005 comb. n

  16. Ümbrikupalk on põhjendamatu kingitus sulist tööandjale / Marek Helm, Kaja Toomsalu

    Index Scriptorium Estoniae

    Helm, Marek, 1973-

    2004-01-01

    Ümbrikupalkadega seonduvaid probleeme ning Maksu- ja Tolliameti ja ametiühingute koostööd ümbrikupalkadega võitlemisel tutvustavad Maksu- ja Tolliameti peadirektori asetäitja ning EAKL-i palgasekretär

  17. MHC Expression on Spleen Lymphocyte Subsets in Genetically Resistant and Susceptible Chickens Infected with Marek's Disease Virus

    DEFF Research Database (Denmark)

    Dalgaard, Tina; Bøving, Mette K.; Handberg, Kurt

    2009-01-01

    cytometry for MHC surface expression. In the spleen, constitutive MHC class I surface expression was found to be highest in homozygous B19, lowest in homozygous B21, and intermediate in heterozygous B19/B21 animals. This was observed on CD4(+), CD8(+), and Bu-1(+) splenic lymphocytes. Chickens of all three...... genotypes were subjected to infection with MD virus (GA strain) and spleen samples from infected as well as MHC-matched negative controls were analyzed at 1, 4, and 8 wk post-infection (p.i.). It was observed that MDV induced an increase in MHC class I expression late in the infection. Thus, MHC class I...... was increased on the surface of CD4(+) cells from infected chickens of all genotypes at 4 and 8 wk p.i. compared with negative controls. Also, MHC class I expression was increased on CD8(+) cells from infected chickens of all genotypes at 4 and 8 wk p.i., except for the homozygous B19 animals, that showed...

  18. Vastastikune sõltuvus : Euroopa Venemaa energialõa otsas / Fiona Hill ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Hill, Fiona

    2006-01-01

    Euroopa ja Venemaa energiakaubanduses valitsevast sõltuvusest. Riikide individuaalne haavatavus, Venemaa suhtlemine Euroopa ja teiste üleilmsete turgudega käib vaid nafta ja gaasi abil, mida võib nõrkuseks lugeda, Venemaa gaasimured. Euroopa strateegia peab püüdlema nafta- ja gaasiimpordi jätkuva geograafilise mitmekesistamise poole, et vähendada sõltuvust Venemaast ja Lähis-Idast. Diagrammid

  19. Euroopa tähendab ausat mängu / Bernard Bot ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Bot, Bernard

    2004-01-01

    Kui paljud eurooplased arvavad, et nad aitavad kaasa ausa mängu reeglite kehtestamisele ja püsimisele, siis Euroopa arvamust iseendast ei jaga sugugi alati teised, näiteks Venemaa, kes sageli suhtub skeptiliselt euroliidu kavatsustesse, ütleb EL-i praeguse eesistujamaa Hollandi välisminister

  20. Plejaadid jõuavad taevasse : transatlantilisus ja laienemine itta / Toomas Hendrik Ilves ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Ilves, Toomas Hendrik, 1953-

    2006-01-01

    Erinevad arusaamad ajaloost lääne- ja idaeurooplaste suhete mõjutajana. Euroopa Liidu vanade ja uute liikmesriikide suhtumisest transatlantilistesse suhetesse. Vene keeles ilmunud ajakirjas: Rossija v globalnoi politike 15. nov. 2006, nr. 6

  1. Integrér les minorités russophones en Estonie / Marek Tamm ; interv. Antoine Jacob

    Index Scriptorium Estoniae

    Tamm, Marek, 1973-

    2007-01-01

    Autor kommenteerib vene vähemuse integratsiooniprobleeme Eestis, Eesti valitsuse otsust teisaldada Teise maailmasõja mälestusmärk Tõnismäelt ning pronkssõduri teisaldamisele järgnenud aprillirahutusi

  2. Norman Davies : kogu ajaloolise tõe kirjapanek pole paratamatult võimalik / Norman Davies ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Davies, Norman, 1939-

    2008-01-01

    Intervjuu Läänes Ida-Euroopa ajalugu tutvustanud Briti ajaloolasega. Vt. samas: Bahovski, Erkki. Puhas ajalugu? Tartu Ülikooli aulas 8. oktoobril 2008 "Presidendi Kärajate" raames toimunud president Toomas Hendrik Ilvese ja Oxfordi ülikooli ajalooprofessori Norman Daviese avalikust kahekõnest. Vestlust juhatas Eesti suursaadik Suurbritannias Margus Laidre. Autori sõnul tahtis Eesti president rääkida tänapäeva poliitikast, N. Davies aga ajaloost

  3. Francis Fukuyama : edukas lõimumine toetub omakasule, mitte kultuurile / Francis Fukuyama ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Fukuyama, Francis

    2007-01-01

    Autor arutleb Huntingtoni tsivilisatsioonide kokkupõrke teooria üle ja väidab, et identiteetide konflikti aitavad ületada institutsioonidele ja reeglitele rajanev rahvusvaheline kord. Vt. samas: F. Fukuyama lühielulugu

  4. Tee Kilkennysse läheb läbi... Liivalaia / William Elliott ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Elliott, William

    2005-01-01

    Suurbritannia diplomaat rõhutab vajadust tunda hästi olukorda selles riigis, mida hakatakse rajama või taas üles ehitama. Ta esitab kolm teesi, mida peaks silmas pidama riigi taasülesehitusel. Nn. riskiriikidega diplomaatiliste sidemete säilitamise tähtsusest. Lisa: Rumalaid diplomaatilistest suhetest loobumisi

  5. Aasta kordaminekud ja vajakajäämised maakonna nimekate inimeste pilgu läbi / interv. Marek Pihlak

    Index Scriptorium Estoniae

    2005-01-01

    Valga maavanem Georg Trashanov, Valga linnapea Margus Lepik, Tõrva linnapea Agu Kabrits, Otepää vallavanem Jaanus Raidal, Valgamaa päästeteenistuse direktor Väino Rimm, AS-i Valga Haigla juhataja Riho Tapfer, Valga politseijaoskonna ülemkomissar Tõnu Kürsa ja MRP ärigrupi juhatuse liige Valter Malm vastavad küsimustele, mis puudutavad kordaminekuid ja vajakajäämisi maakonnas 2005. aastal ning nimetavad eeskuju väärivaid valgamaalasi

  6. Toites neid, kes hammustavad toitja kätt / Jean MacKenzie ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    MacKenzie, Jean

    2005-01-01

    Sõja ja rahu kajastamise instituudi Afganistani esinduse direktor räägib oma kogemustest välisabi andmisel riikide meediasektori edendamiseks, Afganistani ajakirjanike koolitusest. Vt. samas: II humanitaarkohalolek

  7. Organizational Career Growth, Affective Occupational Commitment and Turnover Intentions

    Science.gov (United States)

    Weng, Qingxiong; McElroy, James C.

    2012-01-01

    Survey data, collected from the People's Republic of China, were used to test Weng's (2010) four facet model of career growth and to examine its effect on occupational commitment and turnover intentions. Weng conceptualized career growth as consisting of four factors: career goal progress, professional ability development, promotion speed, and…

  8. Lugemisnoppeid / Toomas Tiivel

    Index Scriptorium Estoniae

    Tiivel, Toomas, 1952-

    2012-01-01

    Tutvustus: Tarand, Andres, Strandberg, Marek. Rahvusliku julgeoleku küsimus : Andres Tarandi ja Marek Strandbergi kriitilised kõned Eesti energeetika arengu asjus. Tallinn, 2010 ; Lauerma, Hannu. Usk, lootus ja ohtlik bluff : julgustamisest vaimse terrorini. Tallinn, 2008

  9. Revision of the subfamily Opiinae (Hymenoptera, Braconidae) from Hunan (China), including thirty-six new species and two new genera

    Science.gov (United States)

    Li, Xi-Ying; van Achterberg, Cornelis; Tan, Ji-Cai

    2013-01-01

    van Achterberg & Li, gen. n. (type species: Areotetes carinuliferus sp. n.) and Coleopioides van Achterberg & Li, gen. n. (type species: Coleopioides postpectalis sp. n. are described. All species are illustrated and keyed. In total 30 species of Opiinae are sequenced and the cladograms are presented. Neopius Gahan, 1917, Opiognathus Fischer, 1972, Opiostomus Fischer, 1972, and Rhogadopsis Brèthes, 1913, are treated as a valid genera based on molecular and morphological differences. Opius vittata Chen & Weng, 2005 (not Opius vittatus Ruschka, 1915), Opius ambiguus Weng & Chen, 2005 (not Wesmael, 1835) and Opius mitis Chen & Weng, 2005 (not Fischer, 1963) are primary homonymsandarerenamed into Phaedrotoma depressa Li & van Achterberg, nom. n., Opius cheni Li & van Achterberg, nom. n. andOpius wengi Li & van Achterberg, nom. n., respectively. Phaedrotoma terga (Chen & Weng, 2005) comb. n.,Diachasmimorpha longicaudata (Ashmead, 1905) and Biosteres pavitita Chen & Weng, 2005, are reported new for Hunan, Opiostomus aureliae (Fischer, 1957) comb. n. is new for China and Hunan; Xynobius maculipennis(Enderlein, 1912) comb. n. is new for Hunan and continental China and Rhogadopsis longuria (Chen & Weng, 2005) comb. n. is new for Hunan. The following new combinations are given: Apodesmia puncta (Weng & Chen, 2005) comb. n., Apodesmia tracta (Weng & Chen, 2005) comb. n., Areotetes laevigatus (Weng & Chen, 2005) comb. n., Phaedrotoma dimidia (Chen & Weng, 2005) comb. n., Phaedrotoma improcera (Weng & Chen, 2005) comb. n., Phaedrotoma amputata (Weng & Chen, 2005) comb. n., Phaedrotoma larga (Weng & Chen, 2005) comb. n., Phaedrotoma osculas (Weng & Chen, 2005) comb. n., Phaedrotoma postuma (Chen & Weng, 2005) comb. n., Phaedrotoma rugulosa (Chen & Weng, 2005) comb. n., Phaedrotoma tabularis (Weng & Chen, 2005) comb. n., Rhogadopsis apii (Chen & Weng, 2005) comb. n., Rhogadopsis dimidia (Chen & Weng, 2005) comb. n., Rhogadopsis diutia (Chen & Weng, 2005) comb. n., Rhogadopsis

  10. Eesti saab Euroopa rahaliidu 17. liikmeks / Andrus Karnau ; kommenteerinud Marek Belka, Angela Merkel, Taavi Veskimägi ja Andrus Ansip

    Index Scriptorium Estoniae

    Karnau, Andrus

    2010-01-01

    1. jaanuaril liitub Eesti euroga. Eesti majandusest. Maailmas on käimas kolm valuutasõda: Hiina jeeni ümber, maailma rikkamate riikide keskpankade ümber ja arenevate riikide valitsuste valuutainterventsioonide ümber

  11. Muutumismäng 2010. 1.-5. osa / tekst Kerttu Soans ; kommenteerinud Tõnis Elling, Maiu Herzmann, Reet Martinson, Marek Sildoja, Pille Mitt, Marko Vilipson

    Index Scriptorium Estoniae

    Soans, Kerttu, 1961-

    2010-01-01

    Ajakirja Üks Muutumismäng 2010 jälgib nende käekäiku, kes soovivad langetada kaalu osaledes spordiklubi Artic Sport XL-treeningprogrammis. Tutvustatakse ka inimest, kes on eeskujuks teistele treenijatele ja kaalulangetajatele

  12. Severe necrotic dermatitis in the combs of line 6-3 chickens is associated with Marek's disease virus-induced immunosuppression

    Science.gov (United States)

    Marek’s disease (MD), a lymphoproliferative disorder of domestic chickens is characterized by bursal–thymic atrophy and rapid onset of T-cell lymphomas that infiltrate lymphoid tissues, visceral organs, and peripheral nerves. Marek’s disease virus (MDV), the etiological agent of MD, is a highly cel...

  13. Genetic susceptibility to and presence of endogenous avian leukosis viruses impose no significant impact on survival days of chickens challenged with very virulent plus Marek's disease virus

    Science.gov (United States)

    Chicks of distinct genotypes at the tumor virus B locus (TVB) in combination with presence or absence of endogenous avian leukosis virus ev21 gene in their genomes were examined for survival day patterns after challenge with very virulent plus Marek’s disease virus (vv+MDV) in three consecutive tria...

  14. Ex uno plures´est e pluribus unum´ini? / Rein Müllerson ; inglise keelest tõlkinud Marek Laane

    Index Scriptorium Estoniae

    Müllerson, Rein, 1944-

    2010-01-01

    Õigusteadlane Rein Müllerson ühiskondliku mitmekesisuse ja homogeensuse arengutest, dissimilatsiooni asendumisest assimilatsiooniga, Ida ja Lääne ühiskondade ühildumisest üleilmastumise protsessis

  15. Kohustiste täitmine ja tagamise vahendid : [bakalaureusetöö] / Marek Sepp ; Tartu Ülikool, õigusteaduskond ; juhendaja: Irene Kull

    Index Scriptorium Estoniae

    Sepp, Marek

    1994-01-01

    Kohustiste täitmine, nõuetekohase täitmise printsiip, vastastikune täitmine, deponeerimine, kohustiste täitmine natuuras; kohustiste täitmise tagamine (käendus, garantii, leppetrahv, käsiraha, pant)

  16. Ajaloo representatsioon ja kogemus : intervjuu Frank Ankersmitiga / Frank Ankersmit ; intervjueerinud Marek Tamm ; ingliskeelsest käsikirjast tõlkinud Märt Väljataga

    Index Scriptorium Estoniae

    Ankersmit, Frank, 1945-

    2015-01-01

    Ajaloo uurimisest ja ajalookirjutusest. Historismist. Leibnizi tähtsusest ajaloofilosoofiale. Poliitilisest filosoofiast. Ajaloo kogemusest ja mineviku mõistest. Ajaloofilosoofiast ja ajalooteooriast

  17. The use of serotype 1-and serotype 3-specific polymerase chain reaction for the detection of Marek's disease virus in chickens

    DEFF Research Database (Denmark)

    Handberg, Kurt; Nielsen, Ole L.; Jørgensen, Poul Henrik

    2001-01-01

    and ovaries. The detection of MDV in feather tips appeared to be as sensitive as co-cultivation of buffy-coat cells, although an inhibiting factor was observed in extracts from feather tips of non-white chickens. This inhibition could be overcome in most extracts by applying a bovine serum albumen...

  18. Down-regulation of MHC Class I by the Marek's Disease Virus (MDV) UL49.5 Gene Product Mildly Affects Virulence in a Haplotype-specific Fashion

    Science.gov (United States)

    Marek’s disease is a devastating neoplastic disease of chickens caused by gallid herpesvirus 2 or Marek’s disease virus (MDV), which is characterized by massive visceral tumors, immune suppression, neurologic syndromes, and peracute deaths. It has been reported that MDV down-regulates surface expre...

  19. Estonski kulturist sõgrajet glavnuju rol v Gollivude

    Index Scriptorium Estoniae

    2008-01-01

    Portaal fitness.ee teatel ootab kulturisti Marek Kalmust roll Hollywoodis, kus Tõnis Carbek olevat stuudiole Pixar Animation esitanud stsenaariumi, mis kirjutatud M. Kalmust peaosalisena silmas pidades

  20. Comparative Study of Human Liver Ferritin and Chicken Liver by Moessbauer Spectroscopy. Preliminary Results

    Energy Technology Data Exchange (ETDEWEB)

    Oshtrakh, M. I. [Ural State Technical University - UPI, Division of Applied Biophysics, Faculty of Physical Techniques and Devices for Quality Control (Russian Federation); Milder, O. B.; Semionkin, V. A. [Ural State Technical University - UPI, Faculty of Experimental Physics (Russian Federation); Prokopenko, P. G. [Russian State Medical University, Faculty of Biochemistry (Russian Federation); Malakheeva, L. I. [Simbio Holding, Science Consultation Department (Russian Federation)

    2004-12-15

    A comparative study of normal human liver ferritin and livers from normal chicken and chicken with Marek disease was made by Moessbauer spectroscopy. Small differences of quadrupole splitting and isomer shift were found for human liver ferritin and chicken liver. Moessbauer parameters for liver from normal chicken and chicken with Marek disease were the same.

  1. Marek’s disease herpesvirus vaccines integrate into chicken host chromosomes yet lack a virus-host phenotype associated with oncogenic transformation

    Science.gov (United States)

    Marek's disease (MD) is a lymphotrophic and oncogenic disease of chickens that can lead to death in susceptible and unimmunized host birds. The causative pathogen, Marek's disease virus (MDV), a highly oncogenic alphaherpesvirus, integrates into host genome near the telomeres during viral latency an...

  2. Comparative Study of Human Liver Ferritin and Chicken Liver by Moessbauer Spectroscopy. Preliminary Results

    International Nuclear Information System (INIS)

    Oshtrakh, M. I.; Milder, O. B.; Semionkin, V. A.; Prokopenko, P. G.; Malakheeva, L. I.

    2004-01-01

    A comparative study of normal human liver ferritin and livers from normal chicken and chicken with Marek disease was made by Moessbauer spectroscopy. Small differences of quadrupole splitting and isomer shift were found for human liver ferritin and chicken liver. Moessbauer parameters for liver from normal chicken and chicken with Marek disease were the same.

  3. Kolm väärt väljapanekut Võru Linnagaleriis / Andrus Raag

    Index Scriptorium Estoniae

    Raag, Andrus, 1982-

    2009-01-01

    Helen Meleski, Katrin Teesi ja Liina Guiteri (ühisnimi Sigmund Freud) näitus "Keemia", Ruti Jõgi joonistuste ja Aivar Rumvoldi maalide näitus "Koos. Omaette", Marek Hämmelbergi (pseudonüüm Marek) joonistuste näitus "Tuvi ämm" 20. novembrini

  4. Neli kulda juunioride MM-ilt. Mis saab edasi? / Märt Roosna

    Index Scriptorium Estoniae

    Roosna, Märt

    2006-01-01

    Juunioride kergejõustiku MM-il Pekingis võitsid eestlased neli kuldmedalit: Kaire Leibak kolmikhüppes, Marek Niit 200 m jooksus, Margus Hunt kuulitõukes ja kettaheites. Lisaks vestlus Kaire Leibaku treeneri Kersti Viruga, Marek Niiduga ja Margus Hundiga

  5. Measuring Work Engagement, Psychological Empowerment, and Organizational Citizenship Behavior Among Health Care Aides.

    Science.gov (United States)

    Ginsburg, Liane; Berta, Whitney; Baumbusch, Jennifer; Rohit Dass, Adrian; Laporte, Audrey; Reid, R Colin; Squires, Janet; Taylor, Deanne

    2016-04-01

    Health care aides (HCAs) provide most direct care in long-term care (LTC) and home and community care (HCC) settings but are understudied. We validate three key work attitude measures to better understand HCAs' work experiences: work engagement (WEng), psychological empowerment (PE), and organizational citizenship behavior (OCB-O). Data were collected from 306 HCAs working in LTC and HCC, using survey items for WEng, PE, and OCB-O adapted for HCAs. Psychometric evaluation involved confirmatory factor analysis (CFA). Predictive validity (correlations with measures of job satisfaction and turnover intention) and internal consistency reliability were examined. CFA supported a one-factor model of WEng, a four-factor model of PE, and a one-factor model of OCB-O. HCC workers scored higher than LTC workers on Self-determination (PE) and lower on Impact, demonstrating concurrent validity. WEng and PE correlated with worker outcomes (job satisfaction, turnover intention, and OCB-O), demonstrating predictive validity. Reliability and validity analyses indicated sound psychometric properties overall. Study results support psychometric properties of measures of WEng, PE, and OCB-O for HCAs. Knowledge of HCAs' work attitudes and behaviors can inform recruitment programs, incentive systems, and retention/training strategies for this vital group of care providers. © The Author 2016. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  6. Tööandja huvide ja õiguste kaitse töösuhetes : [bakalaureusetöö] / Marek Piiroja ; Tartu Ülikooli Õigusinstituut ; juhendaja: Heino Siigur

    Index Scriptorium Estoniae

    Piiroja, Marek

    2005-01-01

    Tööandja õiguslik staatus EV-s 1918-1939, taasiseseisvunud Eesti tööõigusest tulenevad tööandja huvide ja õiguste kaitse, sellega seonduvad probleemid, Eesti tööandjate huvide ja õiguste kaitse erinevusi võrreldes Prantsusmaa tööõiguse ja EL direktiividega

  7. Toidutööstus panustab detsembris jõulutoodetele. Pühad toovad käibelisa / Ain Alvela, Ketlin Rauk ; kommenteerinud Ruth Roht, Marek Viilol, Simmo Kruustük, Imre Sokk

    Index Scriptorium Estoniae

    Alvela, Ain, 1967-

    2011-01-01

    Spetsiaalsed jõulutooted aitavad aasta lõpul suurendada toiduainetööstuste käivet. ASi Atria Eesti müügi- ja turundusdirektori Margus Masingu, ASi Fazer Eesti juhatuse esimehe Kristjan Kongo ja ASi Salvest turundusdirektori Ain Nõlvaku kommentaare

  8. Histoire de lÈstonie et de la nation estonienne : Eesti ja eesti rahvuse ajalugu : intervjuu Jean-Pierre Minaudier̀ga / Jean-Pierre Minaudier ; küsitlenud Marek Tamm

    Index Scriptorium Estoniae

    Minaudier, Jean-Pierre

    2008-01-01

    Intervjuu raamatu "Histoire de lÈstonie et de la nation estonienne" autori, prantsuse ajaloolase Jean-Pierre Minaudier̀ga. Raamatututvustus : Minaudier, Jean-Pierre. Histoire de lÈstonie et de la nation estonienne. Paris : L̀Harmattan, 2007 (Bibliothèque finno-ougrienne; 17)

  9. Convergence theorems for certain classes of nonlinear mappings

    International Nuclear Information System (INIS)

    Chidume, C.E.

    1992-01-01

    Recently, Xinlong Weng announced a convergence theorem for the iterative approximation of fixed points of local strictly pseudo-contractive mappings in uniformly smooth Banach spaces, (Proc. Amer. Math. Soc. Vol.113, No.3 (1991) 727-731). An example is presented which shows that this theorem of Weng is false. Then, a convergence theorem is proved, in certain real Banach spaces, for approximation a solution of the inclusion f is an element of x + Tx, where T is a set-valued monotone operator. An explicit error estimate is also presented. (author). 26 refs

  10. VeriML: A Dependently-Typed, User-Extensible and Language-Centric Approach to Proof Assistants

    Science.gov (United States)

    2013-01-01

    newly-arrived members of the FLINT group, especially Xinyu Feng, Alex Vaynberg, Rodrigo Ferreira, David Costanzo, Shu-Chun Weng, Jan Hoffmann and Mike...Constable, S.F. Allen, H.M. Bromley, W.R. Cleaveland, J.F. Cremer , R.W. Harper, D.J. Howe, T.B. Knoblock, N.P. Mendler, P. Panangaden, et al. Implementing

  11. A comparison of two typical multicyclic models used to forecast the world's conventional oil production

    International Nuclear Information System (INIS)

    Wang Jianliang; Feng Lianyong; Zhao Lin; Snowden, Simon; Wang Xu

    2011-01-01

    This paper introduces two typical multicyclic models: the Hubbert model and the Generalized Weng model. The model-solving process of the two is expounded, and it provides the basis for an empirical analysis of the world's conventional oil production. The results for both show that the world's conventional oil (crude+NGLs) production will reach its peak in 2011 with a production of 30 billion barrels (Gb). In addition, the forecasting effects of these two models, given the same URR are compared, and the intrinsic characteristics of these two models are analyzed. This demonstrates that for specific criteria the multicyclic Generalized Weng model is an improvement on the multicyclic Hubbert model. Finally, based upon the resultant forecast for the world's conventional oil, some suggestions are proposed for China's policy makers. - Highlights: ► Hubbert model and Generalized Weng model are introduced and compared in this article. ► We conclude each model's characteristic and scopes and conditions of applicable. ► We get the same peak production and time of world's oil by applying two models. ► Multicyclic Generalized Weng model is proven slightly better than Hubbert model.

  12. Hiina linna uued ilmed / Katja Koort

    Index Scriptorium Estoniae

    Koort, Katja

    2007-01-01

    Hiina nüüdiskunsti näitus "Linnailmed / City Expressions" Tallinna Kunstihoones kuni 28. I. Osalevad Guangzhou ja Guangzhouga seotud kunstnikud. Kuraatorid Reet Varblane ja Zuo Zhengyao, kujundaja Rosita Raud. Pikemalt Feng Fengi, Yu Xudongi, Zuo Zhengyao, Weng Feni, Li Bangyao ja Hu Xiangqiani töödest

  13. Feature Extraction Without Edge Detection

    Science.gov (United States)

    1993-09-01

    Faugeras & Maybank [24], Weng, Ahuja, & Huang[79]). Consequently, many authors assume that it is solved in their analysis (for example, Broida & Chellappa...D. Faugeras and S. Maybank . Motion from point matches: multiplicity of solutions. International Journal of Computer Vision, 4(3):225-246, June 1990

  14. Anthropometric measurements of HIV-infected children aged one to ...

    African Journals Online (AJOL)

    2015-10-12

    Oct 12, 2015 ... -5Gains in child survival attributed to implementation of survival strategies had been severely eroded by increas- ing mortality for pediatric HIV infections. There is a high level of malnutrition in children in Africa, with one in every under five being malnourished6,7. Weng et al. 8studied the association ...

  15. Synthesis of substituted guanidines using Zn–Al hydrotalcite catalyst

    Indian Academy of Sciences (India)

    Zn–Al HT was prepared by co-precipitation method and charac- terized by ... tion of highly functionalized guanidines.4 Linton et al. explained a ..... Pi C, Zhu Z, Weng L, Chen Z and Zhou X 2007 Chem. Commun. ... J P 2000 J. Mater. Chem.

  16. 1 Analyse du bruit dans un préamplificateur de harge en ...

    African Journals Online (AJOL)

    PR BOKO

    afriquescience.info. Daniel TEKO et al. Analyse du bruit dans un préamplificateur de ...... Nuclear Sciences and Techniques, Vol.21 (5) (2010) 312-315. [5] - M. Weng, et al. A high-speed low-noise CMOS 16-channel charge-sensitive preamplifier ASIC for.

  17. Kui vana on su keha? / Evelin Kivilo-Paas

    Index Scriptorium Estoniae

    Kivilo-Paas, Evelin, 1979-

    2012-01-01

    Keha vanuse testimisest Polar BodyAge'i programmi abil. Treener Kristi Roosimägi analüüsib osalejate, TV3 uudisteankur Marek Lindmaa, ilmateadustaja Liis Lusmäe ja reporter Feliks Unduski tulemusi

  18. Rahvusvaheline raamat Saaremaa vallutamisest / Raul Sulbi

    Index Scriptorium Estoniae

    Sulbi, Raul

    2007-01-01

    Arvustus: Toman, Marek. Saaremaad vallutamas : [lühijutud = The conquest of Saaremaa Island] / [illustreerinud] Jan Ungrád ; tšehhi keelest tõlkinud Leo Metsar ; ingliskeelne tekst: Mimi Rogers. Tallinn : Tiritamm, 2007

  19. Euroopa kohale koondusid mustad murepilved / Jeroen Bult

    Index Scriptorium Estoniae

    Bult, Jeroen

    2005-01-01

    Brüsselis toimunud Euroopa Liidu tippkohtumisel arutatud organisatsiooni eelarvearuteludest, Euroopa jagunemisest kahte leeri. Kommenteerivad Luksemburgi peaminister Jean-Claude Juncker, Prantsusmaa president Jacques Chirac ning Poola peaminister Marek Belka. Lisa: Kahes leeris euroliit

  20. Arhitektura budushtshego / Boris Borissov

    Index Scriptorium Estoniae

    Borissov, Boris

    2008-01-01

    Digitaalkunsti konkurss NVArt Challenge. 2008. a. teemaks oli "Art Space :Architecture and Landscape". Esikoha sai Marek Staszek Poolast projektiga "Complex at the Centre of the Universe". 2 värvilist ill

  1. Koda = Koda / Ülar Mark, Kariina Kristiina Kaufmann, Kadri Tonto ; kommenteerinud Katrin Koov

    Index Scriptorium Estoniae

    Mark, Ülar, 1968-

    2016-01-01

    Minimalistliku vormiga eramu KODA Tallinnas, Järvekalda tee 33. Autorid Ülar Mark, Taavi Jakobson, Hannes Tamjärv, Kalev Ramjalg, Marek Strandberg. Arhitektid Ülar Mark, Kariina Kristiina Kaufmann, Kadri Tonto, Hannes Praks

  2. Meediareklaamiturg kasvab aasta lõpuks kuni kaheksa protsenti / Esta Kaal

    Index Scriptorium Estoniae

    Kaal, Esta, 1962-

    2002-01-01

    Emori uuring: tänu valimistele ja pensionikindlustuse reklaamikampaaniatele on oodata aasta lõpuks kuni 8%-list reklaamituru kasvu. Diagramm. Kommenteerivad Toomas Leito, Toomas Vara ja Marek Reinaas

  3. Tallinn 2011 panustab tänavu turismifirmadesse / Kärt Anvelt, Jan Jõgis-Laats ; kommenteerib Roman Geiser

    Index Scriptorium Estoniae

    Anvelt, Kärt, 1973-

    2010-01-01

    Reklaamibüroo Zavod juht Marek Reinaas annab hinnangu SA Tallinn 2011 eelarvekava turundusosale. Kommunikatsioonispetsialist Daniel Vaarik viitab võimalusele kasutada Tallinn 2011 tutvustamiseks sotsiaalvõrgustikke, nt. Facebooki ja Twitterit

  4. Sissejuhatus sõnavõlur Tolkieni juurde / Neeme Korv

    Index Scriptorium Estoniae

    Korv, Neeme, 1974-

    2003-01-01

    Carpenter, Humphrey. J. R. R. Tolkien : elulugu / inglise keelest tõlkinud Tiina Randus.Tallinn : Tänapäev, 2002 ; Day, David. Tolkieni entsüklopeedia / inglise keelest tõlkinud Marek Laane. Tallinn : Varrak, 2002

  5. Lummav antropoloog, kes vabastas etnograafia lummusest / Eeva Kesküla

    Index Scriptorium Estoniae

    Kesküla, Eeva

    2006-01-01

    Tallinna Ülikoolis 10. novembril toimunud Ameerika kultuuriantropoloogi Clifford Geertzi mälestusõhtust, kus esinesid rektor Rein Raud, Eesti Humanitaarinstituudi lektor Marek Tamm, antropoloogia keskuse dotsent Lorenzo Cañás Bottos ja Stefano Montes

  6. Iga tund võib olla riigikaitsetund / Victoria Parmas

    Index Scriptorium Estoniae

    Parmas, Victoria

    2015-01-01

    Riigikaitseõpetuse seostamisest teiste õppeainetega. Rocca al Mare koolis teevad riigikaitseõpetuse osas koostööd geograafiaõpetaja Marek Nisuma ning ajalooõpetajad Katrin Martsik ja Ronald Juurmaa

  7. Proidi tsherez "igolnoje ushko" / Elena Rudi

    Index Scriptorium Estoniae

    Rudi, Elena

    2007-01-01

    Tallinnas avati pidulikult taastatud Trepi tänav Nõelasilma väravaga. Taastatud väravaehitist ilmestab vanast väravast säilinud barokkstiilis raidreljeef. Taastamisprojekti autor on restauraator Marek Lill

  8. President attacks Seglins on comments / Talis Saule Archdeacon

    Index Scriptorium Estoniae

    Archdeacon, Talis Saule

    2008-01-01

    Läti president kritiseeris Läti siseministrit Mareks Seglinsit, kui viimane kasutas inglaste iseloomustamiseks ebatsensuurset väljendit, saades teada, et Läti Vabadussamba rüvetajateks olid briti kodanikud

  9. Koguteos ristisõjaliikumisest / Maiki Voore

    Index Scriptorium Estoniae

    Voore, Maiki, 1983-

    2011-01-01

    Tutvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia / edited by Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham ; Burlington : Ashgate, 2011

  10. Alguses oli Henrik / Juhan Kreem

    Index Scriptorium Estoniae

    Kreem, Juhan, 1971-

    2012-01-01

    Arvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia / edited by Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham ; Burlington : Ashgate, 2011

  11. [Crusading and chronicle writing on the medieval Baltic frontier: A companion to the chronicle of Henry of Livonia] / Radosław Biskup

    Index Scriptorium Estoniae

    Biskup, Radosław

    2014-01-01

    Arvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the chronicle of Henry of Livonia, eds. Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham ; Burlington (Vt.) : Ashgate, c2011

  12. [Crusading and Chronicle Writing on the Medieval Baltic Frontier: A Companion to the Chronicle of Henry of Livonia] / Michael Amundsen

    Index Scriptorium Estoniae

    Amundsen, Michael

    2012-01-01

    Arvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia / edited by Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham : Ashgate, 2011

  13. Henriku uurimise hetkeseis / Mihkel Mäesalu

    Index Scriptorium Estoniae

    Mäesalu, Mihkel, 1985-

    2011-01-01

    Tutvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia / edited by Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham ; Burlington : Ashgate, 2011

  14. Mõttesügav ajalooteos / Enn Tarvel

    Index Scriptorium Estoniae

    Tarvel, Enn, 1932-

    2012-01-01

    Arvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia / edited by Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham ; Burlington : Ashgate, 2011

  15. Koguteos ristisõdadest Läänemere idarannikul

    Index Scriptorium Estoniae

    2011-01-01

    Tutvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia / edited by Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham ; Burlington : Ashgate, 2011

  16. Clifford Geertzi mälestusõhtu

    Index Scriptorium Estoniae

    2006-01-01

    10. novembril toimub TLÜ-s Ameerika kultuurantropoloogi Clifford Geertzi mälestusõhtu, kus esinevad rektor Rein Raud, TLÜ Eesti Humanitaarinstituudi antropoloogia keskuse dotsent Lorenzo Cañás Bottos ja kultuuriteooria lektor Marek Tamm

  17. Seltskond / Annika Haas

    Index Scriptorium Estoniae

    Haas, Annika

    2006-01-01

    Tallinna Ülikoolis toimunud ameerika kultuurantropoloogi Clifford Geertzi mälestusõhtust, kus esinesid rektor Rein Raud, Eesti Humanitaarinstituudi dotsent Lorenzo Cañás Bottos ja kultuuriteooria lektor Marek Tamm

  18. Kultuurantropoloog Clifford Geertzi mälestusõhtu

    Index Scriptorium Estoniae

    2006-01-01

    Tallinna Ülikoolis peetakse homme Ameerika kultuurantropoloogi Clifford Geertzi mälestusõhtut, esinevad rektor Rein Raud, Eesti Humanitaarinstituudi dotsent Lorenzo Cañás Bottos ja kultuuriteooria lektor Marek Tamm

  19. Mazeikiu avoids fine, gets new CEO

    Index Scriptorium Estoniae

    2007-01-01

    Leedu naftatöötlustehase Mazeikiu Nafta uueks tegevjuhiks saab Marek Mroczkowski. Endine juht Paul Nelson English tasus võimaluse eest kodumaale naasta kautsjoni. Ettevõtet ähvardas trahv turul domineerimise eest

  20. Geenmuundatud taimed võivad vallutada maailma / Riho Laurisaar

    Index Scriptorium Estoniae

    Laurisaar, Riho

    2005-01-01

    Eelmisel neljapäeval Tartus Briti nõukogu ja TÜ AHHAA teaduskeskuse korraldatud üritusel Café Scientifique vaidlesid Marek Strandberg ja briti biotehnoloog Ray Mathias geneetiliselt muundatud taimede ohtlikkuse üle

  1. Odpověď Marku Tomanovi

    Czech Academy of Sciences Publication Activity Database

    Trávníček, Jiří

    2014-01-01

    Roč. 30, č. 3 (2014), s. 5 ISSN 1211-9938 Institutional support: RVO:68378068 Keywords : Toman, Marek * Iturbe, Antonio G. * Spanish prose * literary reviews Subject RIV: AJ - Letters, Mass-media, Audiovision

  2. Riigikogu pikendas eile Iraagi ja Kosovo missiooni veel aastaks / Maria-Elisa Rannajõe

    Index Scriptorium Estoniae

    Rannajõe, Maria-Elisa

    2007-01-01

    Iraagi ja Kosovo missiooni pikendamisest Riigikogus, roheliste erakonna juhi Marek Strandbergi arvamus Iraagi missiooni pikendamise kohta. ÜRO Julgeolekunõukogu pikendas liitlasvägede mandaati Iraagis aasta võrra, Iraak palus missiooni pikendamist viimast korda

  3. [Marge Rennit. Eesti muuseumid / Estonian museums] / Tapio Mäkeläinen

    Index Scriptorium Estoniae

    Mäkeläinen, Tapio

    2009-01-01

    Tutvustus: Eesti muuseumid = Estonian museums / [Eesti Muuseumiühing ; koostaja Marge Rennit ; tõlkija Tiina Mällo ; toimetaja Ivi Tammaru ; eessõna: Piret Õunapuu ; kujundaja Marek Allvee]. Tallinn : Oomen, 2008

  4. Uus kord tõi nurina / Jaana Pikalev

    Index Scriptorium Estoniae

    Pikalev, Jaana

    2010-01-01

    IT-eksperdid Tõnu Samuel ja Jaan Jänesmäe peavad domeenireformi läbikukkunuks ning on koostanud avaliku kirja, milles kritiseerivad Eesti Interneti Sihtasutuse juhte Marek-Andres Kautsi ja Jaak Lippmaad

  5. 27. IV-18. V on Tallinna Matkamajas avatud...

    Index Scriptorium Estoniae

    2001-01-01

    Näitus "10 viimast aastat poola restaureerimises", millele eelnes seminar "Mälestiste kaitse ja restaureerimine Poolas". Põhiettekanne Marek Barazhskilt. Poola-Eesti restaureerimisalase koostöö jätkamisest.

  6. 50th Annual Technical Meeting of the Society of Engineering Science (SES)

    Science.gov (United States)

    2014-08-15

    2:00 PM 30 Sess Micr Tuesda ion Chai omecha y 8:00 - 8 rs: Dimit nics and S Georg :50 Salom ris Lagou ome Asp C e Weng ( Tuesday Award on 101...College of New York), Shahab Shojaei-Zadeh (Rutgers University), Kevin Connington (The Levich Institute), Jeffrey Morris (Levich Institute and Dept. of...Duisburg-Essen) MECHANICS OF FLUIDS AND THERMAL SYSTEMS Complex Fluids: Suspensions, Emulsions, and Gels Barus-Holley 160 Session Chairs Jeffrey Morris

  7. Dirac cone protected by non-symmorphic symmetry and three-dimensional Dirac line node in ZrSiS

    OpenAIRE

    Schoop, Leslie M.; Ali, Mazhar N.; Straßer, Carola; Topp, Andreas; Varykhalov, Andrei; Marchenko, Dmitry; Duppel, Viola; Parkin, Stuart S. P.; Lotsch, Bettina V.; Ast, Christian R.

    2016-01-01

    Materials harboring exotic quasiparticles, such as Dirac and Weyl fermions\\cite{xu2015discovery,borisenko2015time,weng2015weyl,xu2015observation}, have garnered much attention from the physics and material science communities. These fermions are massless and, in some materials, have shown exceptional physical properties such as ultrahigh mobility and extremely large magnetoresistances \\cite{liang2015ultrahigh,ali2014large,du2015unsaturated,shekhar2015large}. Recently, new materials have been ...

  8. Data-Model Assimilation at the FACE and AmeriFlux Sites Toward Predictive Understanding of Carbon Sequestration at Ecosystem and Regional Scales

    Energy Technology Data Exchange (ETDEWEB)

    Luo, Yiqi [Univ. of Oklahoma, Norman, OK (United States)

    2013-01-09

    The project was conducted during the period from 9/1/2007 to 8/31/2011 with three major tasks: (1) development of data assimilation (DA) techniques for terrestrial carbon research; (2) applications of DA techniques to analysis of carbon cycle at Duke and other FACE sites; and (3) inverse analysis at AmeriFlux sites. During this period, we have developed a variety of techniques, including (1) ensemble Kalman filter to estimate model parameters or state variables (Gao et al. 2011), (2) Conditional inversion to estimate parameters of a carbon cycle model (Wu et al. 2009), and (3) various methods to quantify uncertainty of estimated parameters and predicted C sinks (e.g., Weng et al. 2011), and (4) information theory to evaluate information content of different model structures and data sets (Weng and Luo 2011). We applied the DA techniques to and did modeling at the Duke FACE and other global change experimental sites. We addressed the following issues: (1) interactive effects of CO2, warming and precipitation on ecosystem processes (e.g., Luo et al. 2008, Weng and Luo 2008, Zhou et al. 2008), (2) effects of warming on estimated parameters related to photosynthesis and residence times (Zhou et al. 2010); and (3) uncertainty in estimated parameters and predicted C sequestration (Gao et al. 2011, Weng and Luo 2011). In addition, we have done data assimilation to estimate carbon residence and carbon sequestration in US continent (Zhou and Luo 2008) and temperature sensitivity at the global scale (Zhou et al. 2009).

  9. Herpesvirus of turkeys: microarray analysis of host gene responses to infection

    International Nuclear Information System (INIS)

    Karaca, Gamze; Anobile, Jonathan; Downs, Danielle; Burnside, Joan; Schmidt, Carl J.

    2004-01-01

    Herpesvirus of turkeys (HVT) provides an economically important live vaccine for prevention of Marek's disease (MD) of chickens. MD, characterized by both immunosuppression and T-cell lymphoma, is caused by another herpesvirus termed Marek's disease virus (MDV). Microarrays were used to investigate the response of chicken embryonic fibroblasts (CEF) to infection with HVT. Genes responding to HVT infection include several induced by interferon along with others modulating signal transduction, transcription, scaffolding proteins, and the cytoskeleton. Results are compared with earlier studies examining the responses of CEF cells to infection with MDV

  10. Protestibiennaal kunsti suukorvistamise vastu / Margit Tõnson

    Index Scriptorium Estoniae

    Tõnson, Margit, 1978-

    2006-01-01

    Tšetšeenia toetuseks organiseeritud rahvusvahelisest rändnäitusest "Emergency Biennale" Tallinna Kunstihoones, kuraator Evelyne Jouanno. Kaasaegse Kunsti Eesti Keskuse korraldatud ettekandepäevast "Kunstniku moraalsed valikud liberaalse demokraatia ja islami kokkupõrgetes", kus esinevad Margit Sutrop, Johannes Saar, Marek Järvik, Ene-Liis Semper, Eero Epner

  11. A nine - year retrospective study of avian neoplastic diseases in ...

    African Journals Online (AJOL)

    Avian neoplastic diseases have been identified as one of the leading causes of mortality and production losses in commercial chickens in Nigeria. Although available reports described the trend of Marek's disease in Zaria, Kaduna state, they did not take cognizance of other neoplastic diseases of poultry hence the need for ...

  12. Walter Benjamin ja lugemismõnu / Aija Sakova-Merivee

    Index Scriptorium Estoniae

    Sakova-Merivee, Aija, 1980-

    2014-01-01

    Arvustus: Benjamin, Walter. Lapsepõlv Berliinis 1900. aasta paiku : valik esseid. II / Walter Benjamin ; saksa keelest tõlkinud Mati Sirkel ; koostanud ja järelsõna: Marek Tamm. Tallinn : Kultuurileht, 2014. (Loomingu raamatukogu ; 2014, nr. 9/11)

  13. Loskutovs' fate still in the balance

    Index Scriptorium Estoniae

    2007-01-01

    Läti seimi õiguskomisjoni juht Mareks Seglins ütles ajakirjanikele, et valitsusel polnud piisavalt andmeid otsustamaks korruptsioonitõrje büroo juhi Loskutovsi vallandamise üle. Peaminister Aigars Kalvitis tõrjus peaprokuratuuri protesti seoses korruptsioonitõrje büroo juhi Aleksejs Loskutovsi ametist vabastamisega

  14. Lavakad, 23. lend / Eva Kübar

    Index Scriptorium Estoniae

    Kübar, Eva

    2008-01-01

    Eesti Muusika- ja Teatriakadeemia lavakunstikooli XXIII lennu lõpetajatest - näitlejad Marek Tammets, Ago Soots, Agnes Aaliste, Martin Mill, Andres Oja, Juss Haasma, Maarja Mitt, Meelis Põdersoo, Jekaterina Novosjolova, Elina Pähklimägi ja Kristo Viiding, dramaturgid Marion Jõepera, Mart Kase ja Maria Lee Liivak ning lavastajad Robert Annus ja Uku Uusberg

  15. Koda = Koda / Kadri Tonto

    Index Scriptorium Estoniae

    Tonto, Kadri

    2016-01-01

    Minimalistliku vormiga eramu KODA. Kontseptsiooni autorid Ülar Mark, Taavi Jakobson, Hannes Tamjärv, Kalev Ramjalg, Marek Strandberg; arhitektid Ülar Mark, Kariina Kristiina Kaufmann, Kadri Tonto, Hannes Praks. Eesti Arhitektide Liidu preemia "Väike 2013-2015" laureaat

  16. Why Do Athletes Drink Sports Drinks? A Learning Cycle to Explore the Concept of Osmosis

    Science.gov (United States)

    Carlsen, Brook; Marek, Edmund A.

    2010-01-01

    Why does an athlete reach for a sports drink after a tough game or practice? The learning cycle presented in this article helps students answer this question. Learning cycles (Marek 2009) are designed to guide students through direct experiences with a particular concept. In this article, students learn about "osmosis," or the moving of water into…

  17. Maksustatava väärtuse vähendamine osalise või täieliku mittetasumise korral

    Index Scriptorium Estoniae

    2010-01-01

    Ajakirja Raamatupidamisuudised peatoimetaja Jelizaveta Litau päring EL käibemaksudirektiivi 2006/112/EÜ ja Eesti käibemaksuseaduse § 29 lõige 7 kohta ning Rahandusministeeriumi aktsiisi- ja tollipoliitika osakonna juhataja Marek Uusküla vastus

  18. Reformierakond naudib ülisuurt toetust / Agnes Kuus

    Index Scriptorium Estoniae

    Kuus, Agnes

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke, 15. mai 2007, lk. 3. Uuringufirma TSN Emor korraldatud küsitluse kohaselt oli Reformierakonna toetus pärast pronkssõduri sündmusi 46%. Diagramm: Toetus parlamendierakondadele. Kommenteerivad: Kadri Must, Marek Strandberg, Jaanus Marrandi, Margus Tsahkna, Eiki Nestor. Vt. samas: Kai Kalamees. Võimupartnerid usuvad endasse

  19. Milline on Saare maakonna ettevõtjate koostöö / Vilma Rauniste

    Index Scriptorium Estoniae

    Rauniste, Vilma

    2007-01-01

    Saaremaa ettevõtete, omavalitsuste, koolitusasutuste ja riigi esindajad arutasid maakonna tulevikku. Vt. samas: Kohalviibinute arvamusi organisatsiooni loomise kohta. Arvamust avaldavad: Aadu Keskpaik, Marek Lepamets, Tullio Liblik, Villu Vatsfeld, Jüri Aus, Enn Meri, Riivo Asuja, Tarmo Sink, Robert Pajussaar, Kalle Koov

  20. Olend väljastpoolt meie maailma / Raul Sulbi

    Index Scriptorium Estoniae

    Sulbi, Raul

    1995-01-01

    Arvustus: Olend väljastpoolt meie maailma : [Ulmelood] / Koost. Jüri Kallas; Tlk. Jüri Kallas, Sander Kingsepp, Marek Laane, Leo Metsar; Ill. Ants Jaanimägi ja Christina Kuhi; Kujund. Juhan Enniko. Trt.: Elmatar, 1995. (Öölane; 1001).

  1. 13.-20. IV viiakse Kütioru Avatud Ateljees läbi metsakunsti projekt

    Index Scriptorium Estoniae

    2005-01-01

    Osalevad "isekasvava arhitektuuri" (evolutionary architecture) teooria rajaja John Frazer Londonist ning Hollandi arhitektuuribürood S333 ja Onix. Käsitletakse Eesti metsade võsastumise temaatikat. 19. IV Eesti Kunstiakadeemias seminar, lisaks väliskülalistele esinevad Marek Strandberg, Ivar Puura jt.

  2. Noormees sai Eesti Päevalehe abiga magistrikraadi / Piia Puuraid

    Index Scriptorium Estoniae

    Puuraid, Piia

    2013-01-01

    Eile sai magistrikraadi Marek Süld, kelle isa Mati Süld Eesti Päevalehest tasuta õpingud võitis. Eesti Päevaleht loosis 2010. aastal välja 13 tasuta Estonian Business Schooli bakalaureuse- või magistriprogrammi

  3. Kodukeemia hävitab meie tervist iga päev / Linda Raska

    Index Scriptorium Estoniae

    Raska, Linda

    2007-01-01

    Vt. ka Postimees : na russkom jazõke 11. okt., lk. 13. Eestimaa Looduse Fondi ja keskkonnakaitseorganisatsiooni Greenpeace eelmisel aastal korraldatud uuringul osalenud riigikogu liige ja keskkonnakaitsja Marek Strandberg tunnistab, et üritab toime tulla võimalikult vähese kodukeemiaga. Lisa: Looduslikud puhastusnipid

  4. white leghorn chimeras based on bone marrow mesenchymal stem

    African Journals Online (AJOL)

    stem cells (BMMSCs), and to assess its immune tolerance based on variations in proportion of ... Keywords: Bone marrow mesenchymal stem cells, Immune tolerance, ... in tissue injury, transplantation, and ..... 0.05, **p < 0.01; (b) expression of the duck gene in different organs .... CD30hi Marek's disease lymphoma cell.

  5. Klaasist ringhäälingumaja tuleb energiasäästlik

    Index Scriptorium Estoniae

    2007-01-01

    Kultuuriminister Laine Jänes vastuseks erakonna Eestimaa Rohelised Riigikogu fraktsiooni aseesimehe Marek Strandbergi päringule uue ringhäälingumaja energiakuludest. Hoone projekteerimisel võetakse aluseks arhitektuurivõistluse võidutöö, mille autor on taani arhitekt Erik Nobel

  6. 27 November 2014 - Warsaw University of Technology (PL) Vice-Rector for Research R. Bacewicz visitng the ALICE control room and undergorund experimental area with WUT students, accompanied by A. Charkiewicz and A. Siemko; joint signature ceremony with HNINP Director-General M. Jezabek

    CERN Multimedia

    Guillaume, Jeanneret

    2014-01-01

    CERN-PHOTO-201411-245-95: from left to right: Professor D.Sc.Ph.D. Rajmund Bacewicz, Vice-Rector for Research, Warsaw University of Technology, CERN Director-General R. Heuer and Prof. Marek Jeżabek, Director-General, Henryk Niewodniczanski Institute of Nuclear Physics, Republic of Poland

  7. Fostering international cooperation in the field of raw materials - the intraw project and the European international observatory for raw materials

    CSIR Research Space (South Africa)

    Murguía, D

    2016-10-01

    Full Text Available Tafazoli 17 A NEW DECISION SUPPORT TOOL FOR FAULT DIAGNOSIS, HAZARD PREDICTION AND ANALYSIS IN MINING INDUSTRY | Marek Sikora, Wojciech Moczulski, Piotr Przystałka, Dominik Ślęzak, Anna Timofiejczuk 28 A NEW DECISION SUPPORT TOOL FOR FAULT DIAGNOSIS...

  8. Ajalooteaduses pole absoluutset tõde olemas / Ralf R. Parve

    Index Scriptorium Estoniae

    Parve, Ralf R., 1946-2008

    2007-01-01

    4. oktoobril Tallinna Ülikoolis toimunud ümarlauast "Alternatiivsetest ajalookäsitlustest", kus ajaloo uurimise üle arutlesid ajaloolane Mart Laar, TLÜ Eesti Humanitaarinstituudi kultuuriteooria lektor Marek Tamm, TLÜ Ajaloo Instituudi direktor Magnus Ilmjärv ja TLÜ poliitikateooria professor Rein Ruutsoo. Ümarlauda juhtis rektor Rein Raud

  9. Police apathy on the rise / Monika Hanley

    Index Scriptorium Estoniae

    Hanley, Monika

    2008-01-01

    Läti politseinike palkade samale tasemele jätmine on muutnud nad oma töö suhtes ükskõiksemaks. Siseminister Mareks Seglins'e sõnul anti politseinikele nende palgatõusu suhtes vale informatsiooni

  10. Scanforesti Purila saetööstus müüdi eksjuhile

    Index Scriptorium Estoniae

    2004-01-01

    Pankrotistunud puidutööstuse Scanforest Purila saetööstus müüdi Marek Krippeli firmale OÜ Johanna Grupp, Scanforesti vara hulka kuuluv Näpi sae- ja höövlitööstus on aga seni müümata. Nõudeid Scanforesti vastu on 81,5 miljoni krooni eest

  11. A shot from a distance. On Pierwsza piątka (The First Five by Stanisław Barańczak

    Directory of Open Access Journals (Sweden)

    Marek Hendrykowski

    2016-12-01

    Full Text Available Marek Hendrykowski’s article provides an analysis and interpretation of Barańczak’s well-known poem “Pierwsza piątka” [The First Five], whose main characters are the basketball legends of Boston Celtics, NBA champions on many occasions.

  12. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... Paul D. Nuñez1 Marek Nowakowski2. Department of Physics & Astronomy, University of Utah, 115 S 1400 E, Salt Lake City, UT 84112 and Observatorio Astronómico, Universidad Sergio Arboleda, Cll. 74 No. 14–14, Bogotá, Colombia. Departamento de Física, Universidad de los Andes, Cra. 1E No.

  13. Eesti paviljon "Koda" = Estonian pavilion "Koda"

    Index Scriptorium Estoniae

    2015-01-01

    Eesti paviljon "Koda" Hollandi maailmanäitusel "Floriade". Arhitektuurivõistlus 2011. Arhitektid Joel Kopli, Koit Ojaliiv (Kuu Arhitektid), konstruktorid Alar Hammer, Marek Suursalu (Projekt 363). Lauad Kristel Jakobson (Haka Disain), toolid Aap Piho (Maast Furniture), valgustid Margus Triibmann (Keha3)

  14. Tants / Eduard Tido, Janika Sarantshina ; interv. Mel Shiffer

    Index Scriptorium Estoniae

    Tido, Eduard

    2007-01-01

    Oma harrastusest räägivad hip-hop tantsijad Eduard Tido, Janika Sharantshina, Eva Ottas, show-tantsija Helen Randmäe, club freestyle autor Monika Tuvi, dance hall'i maaletooja Helen Lõhmus ja breikar Marek Vetik

  15. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics. Arun Kumar Pati. Articles written in Pramana – Journal of Physics. Volume 56 Issue 2-3 February-March 2001 pp 393-401 Quantum information processing. Interference due to coherence swapping · Arun Kumar Pati Marek Zukowski · More Details Abstract Fulltext PDF.

  16. Kas inimkond näeb aastat 2106? / Stephen Hawking

    Index Scriptorium Estoniae

    Hawking, Stephen W., 1942-

    2006-01-01

    Briti füüsik Stephen Hawking avas Yahoo! internetifoorumis debati, küsides foorumikasutajatelt: "Maailmas valitseb poliitiline, sotsiaalne ja ökoloogiline kaos - kuidas suudab inimkond järgmised sada aastat üle elada?". Kommenteerivad julgeolekuekspert Eerik-Niiles Kross, meditsiiniteaduste doktor Mari Järvelaid ja keskkonnaekspert Marek Strandberg

  17. Tamkivi : Natura alad on ebaolulised / Ulvar Käärt

    Index Scriptorium Estoniae

    Käärt, Ulvar, 1982-

    2007-01-01

    Autori väitel on uus keskkonnaminister Jaanus Tamkivi seadnud kahtluse alla üle-euroopalise tähtsusega Natura 2000 kaitsealade vajalikkuse. Riigikogu liikme Aleksei Lotmani, Eestimaa Looduse Fondi juhatuse liikme Jüri-Ott Salmi hinnanguid. Kommenteerib Hannes Veinla. Vt. ka Aleksei Lotmani ja Marek Strandbergi kommentaare 12. apr. Meie Maa lk. 2

  18. The Effect of Spray Initial Conditions on Heat Release and Emissions in LDI CFD Calculations (Preprint)

    Science.gov (United States)

    2008-06-01

    Shih, T.-H., Povinelli , L. A., Liu, N.-S and Chen, K.-H., (2000), “Generalized Wall Function for...J. Marek, T. D. Smith, N.-S. Liu, and L. A. Povinelli (NASA, Glenn Research Center, Cleveland, OH, “A Study of Hydrogen/Air Combustor Using NCC

  19. "Klass : elu pärast" võitis peaauhinna

    Index Scriptorium Estoniae

    2009-01-01

    Genfis toimunud rahvusvahelisel festivalil Cinema Tous Ecrans sai telesarjade võistlusprogrammis peaauhinna ETV sari "Klass : elu pärast", produtsent Gerda Kordemets, stsenarist Margit Keerdo, režissöörid Ilmar Raag, Gerda Kordemets, Liina Paakspuu, Priit Valkna ja Marek Miil

  20. "Klass : elu pärast" võitis rahvusvahelisel festivalil peaauhinna

    Index Scriptorium Estoniae

    2009-01-01

    Genfis toimunud rahvusvahelisel festivalil Cinema Tous Ecrans sai telesarjade võistlusprogrammis peaauhinna ETV sari "Klass : elu pärast", produtsent Gerda Kordemets, stsenarist Margit Keerdo, režissöörid Ilmar Raag, Gerda Kordemets, Liina Paakspuu, Priit Valkna ja Marek Miil

  1. Võru linnagaleriis avati kolm uut näitust

    Index Scriptorium Estoniae

    2009-01-01

    26. oktoobrist 20 novembrini on Võru Linnagaleriis avatud Ruti Jõgi joonistuste ja Aivar Rumvoldi maalide näitus "Koos. Omaette", Marek Hämmelbergi isikunäitus "Tuvi ämm" ning grupi Sigmund Freud (Liina Guiter, Katrin Tees, Helen Melesk) näitus "Keemia"

  2. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Pseudorapidity distributions of charged particles in Pb–Pb collisions at super proton synchrotron energies from the NA50 experiment. Marek Idzik M C Abreu B Alessandro C Alexa R Arnaldi M Atayan C Baglin A Baldit M Bedjidian S Beolè V Boldea P Bordalo G Borges A Bussière L Capelli C Castanier J Castor B Chaurand ...

  3. Marek’s disease virus induced transient atrophy of cecal tonsils

    Science.gov (United States)

    Although bursal and thymic atrophy associated with Marek’s disease (MD) is well established and characterized, the effect of Marek's disease virus (MDV) infection on lymphoid aggregates within the gut-associated lymphoid tissue (GALT) is not known. The cecal tonsils (CT) are the two largest lympho...

  4. Author Details

    African Journals Online (AJOL)

    Studies of some risk factors for re-introduction and spread of highly-pathogenic avian influenza in two states of Nigeria Abstract PDF · Vol 35, No 1 (2014) - Articles Farmers' Awareness of Marek's Disease and Biosecurity Practices in Poultry Production in Selected States of Nigeria Abstract PDF. ISSN: 0331-3026.

  5. Kohus tühistas Kofkini firma konkursivõidu / Urmas Seaver

    Index Scriptorium Estoniae

    Seaver, Urmas, 1973-

    2008-01-01

    Tallinna halduskohus tühistas Tallinna kesklinna vanema Marek Jürgensoni käskkirja, millega ärimees Aleksander Kofkin sai vanalinnas enda kätte endise Pärli kohviku ruumid, sest Kofkini firma Meriton Food Boutique OÜ võitis Kesklinna valitsuse korraldatud konkursi

  6. Haapsalus hakkab õudne / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2006-01-01

    PÖFF-i abiga toimub Haapsalus õudusfilmide festival, idee autoriks reklaamiagentuuri Zavood juht Marek Reinaas. Eesti Kunstiakadeemia tudengid esinevad videoinstallatsioonide ja perfomance'ite eriprojektiga "Hirmurõõm". Lisatud festivali programmijuhi Helmut Jänese vastus ekstreemse õudusfilmi "Kannibali holokaust" näitamise kohta

  7. Provensálská ves a moravská města mezi středověkem a raným novověkem. Alleins 16. století v kontextu vědeckého díla Jaroslava Marka

    Czech Academy of Sciences Publication Activity Database

    Sterneck, Tomáš

    2016-01-01

    Roč. 135, č. 2 (2016), s. 421-443 ISSN 0323-052X Institutional support: RVO:67985963 Keywords : history * historians * Jaroslav Marek Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

  8. Provintsi veinivabrik ajas võmmid tülli / Mihkel Kärmas

    Index Scriptorium Estoniae

    Kärmas, Mihkel, 1974-

    2003-01-01

    Ärikonflikt provintsifirmas jagas kahte leeri hämara taustaga ärimehed, mõlemad osapooled leidsid endale eestkostja politseist. Arveteklaarimises osalesid ärimehed Igor Zavizion ja Jüri Plukk ning Marek Helinurm ja Eero Einmann Tallinna politseist

  9. Research update: Avian Disease and Oncology Laboratory avian tumor viruses

    Science.gov (United States)

    Genomics and Immunogenetics Use of genomics to identify QTL, genes, and proteins associated with resistance to Marek’s disease. Marek’s disease (MD), a lymphoproliferative disease caused by the highly oncogenic herpesvirus Marek's disease virus (MDV), continues to be a major disease concern to the p...

  10. .* Nigerian Veterinary Journal

    African Journals Online (AJOL)

    'Central Diagnostic, National Veterinary Research Institute Vom, Plateau State, Nigeria, 'Department of Veterinary Medicine. Ahmadu Bello ..... environment as reported by (Olabode et al., 2009; Okwor and Eze, 2011;Jwander et al., 2013b). Farmers who had the same complaints of. Marek's disease from the same source of.

  11. Küla arengukava on külaarengu toetuse saamiseks vajalik / Ain Lember

    Index Scriptorium Estoniae

    Lember, Ain

    2004-01-01

    Liikumine Kodukant kavatseb esitada põllumajandusministeeriumile protestikirja, kuna ei nõustu ministeeriumi infopäevadel levitatava tõlgendusega nagu võiks külade taastamise ja arendamise meetme toetust taotleda ka ilma küla arengukavata. Arvamust avaldavad: Maris Ode, Lemmi Maasik, Heli Raamets, Marek Raud ja Sille Rähn

  12. Organizational Storytelling for Librarians: Using Stories for Effective Leadership

    Science.gov (United States)

    Marek, Kate

    2011-01-01

    Just as literature can be used for learning, the power of storytelling can be very effective when applied to leadership and management. Library expert and author Marek shows readers how they can use storytelling to communicate vision and values with: (1) A primer on how to develop storytelling skills; (2) Tips on how to use narratives to navigate…

  13. Kunstnike moraalsed valikud kultuurikonfliktides = The moral choices of artists in cultural conflicts

    Index Scriptorium Estoniae

    2006-01-01

    Kaasaegse Kunsti Eesti Keskuse 4. ettekannete päev "Kunstnike moraalsed valikud kultuurikonfliktides" sarjast "Lisandusi eesti kunstiloole" Tallinna Kunstihoones 27.04.2006. Kava, esinevad Margit Sutrop, Johannes Saar, Andres Tali, Marek Järvik, Ene-Liis Semper ja Eero Epner, Marco Laimre. Soome filmirežissööri Pirjo Honkasalo dokumentaalfilmi "Melanhoolia kolm tuba" presentatsioon

  14. On the validity of the arithmetic-geometric mean method to locate the optimal solution in a supply chain system

    Science.gov (United States)

    Chung, Kun-Jen

    2012-08-01

    Cardenas-Barron [Cardenas-Barron, L.E. (2010) 'A Simple Method to Compute Economic order Quantities: Some Observations', Applied Mathematical Modelling, 34, 1684-1688] indicates that there are several functions in which the arithmetic-geometric mean method (AGM) does not give the minimum. This article presents another situation to reveal that the AGM inequality to locate the optimal solution may be invalid for Teng, Chen, and Goyal [Teng, J.T., Chen, J., and Goyal S.K. (2009), 'A Comprehensive Note on: An Inventory Model under Two Levels of Trade Credit and Limited Storage Space Derived without Derivatives', Applied Mathematical Modelling, 33, 4388-4396], Teng and Goyal [Teng, J.T., and Goyal S.K. (2009), 'Comment on 'Optimal Inventory Replenishment Policy for the EPQ Model under Trade Credit Derived without Derivatives', International Journal of Systems Science, 40, 1095-1098] and Hsieh, Chang, Weng, and Dye [Hsieh, T.P., Chang, H.J., Weng, M.W., and Dye, C.Y. (2008), 'A Simple Approach to an Integrated Single-vendor Single-buyer Inventory System with Shortage', Production Planning and Control, 19, 601-604]. So, the main purpose of this article is to adopt the calculus approach not only to overcome shortcomings of the arithmetic-geometric mean method of Teng et al. (2009), Teng and Goyal (2009) and Hsieh et al. (2008), but also to develop the complete solution procedures for them.

  15. Review of the East Palaearctic and North Oriental Psyttalia Walker, with the description of three new species (Hymenoptera, Braconidae, Opiinae).

    Science.gov (United States)

    Wu, Qiong; van Achterberg, Cornelis; Tan, Jiang-Li; Chen, Xue-Xin

    2016-01-01

    The East Palaearctic and North Oriental species of the genus Psyttalia Walker (Hymenoptera, Braconidae, Opiinae) are reviewed. Three new species are described and illustrated: Psyttalia latinervis Wu & van Achterberg, sp. n . and Psyttalia majocellata Wu & van Achterberg, sp. n . from China, and Psyttalia spectabilis van Achterberg, sp. n. from Japan. Coeloreuteus formosanus Watanabe, 1934, Opius (Lissosema) proclivis Papp, 1981, Opius (Psyttalia) subcyclogaster Tobias, 1998, Opius (Psyttalia) darasunicus Tobias, 1998, Opius (Psyttalia) cyclogastroides Tobias, 1998, Psyttalia extensa Weng & Chen, 2001, and Rhogadopsis longicaudifera Li & van Achterberg, 2013, are new synonyms of Psyttalia cyclogaster (Thomson, 1895); Opius (Psyttalia) ophthalmicus Tobias, 1977, and Opius (Psyttalia) brevitemporalis Tobias, 1998, of Psyttalia carinata (Thomson, 1895) and both Opius (Psyttalia) vacuus Tobias, 1998, and Opius (Lissosema) longurius Chen & Weng, 1995, of Rhogadopsis mediocarinata (Fischer, 1963). Phaedrotoma daghestanicum (Telenga, 1950), Rhogadopsis mediocarinata (Fischer, 1963) and Rhogadopsis mystica (Fischer, 1963) are new combinations. New records are Psyttalia carinata (Thomson, 1895) from The Netherlands and Norway, and Psyttalia cyclogaster (Thomson, 1895) from Japan. A lectotype is designated for Psyttalia carinata (Thomson, 1895) and Psyttalia cyclogaster (Thomson, 1895). A key to the East Palaearctic and North Oriental species of the genus Psyttalia Walker is included.

  16. Review of the East Palaearctic and North Oriental Psyttalia Walker, with the description of three new species (Hymenoptera, Braconidae, Opiinae

    Directory of Open Access Journals (Sweden)

    Qiong Wu

    2016-11-01

    Full Text Available The East Palaearctic and North Oriental species of the genus Psyttalia Walker (Hymenoptera, Braconidae, Opiinae are reviewed. Three new species are described and illustrated: P. latinervis Wu & van Achterberg, sp. n. and P. majocellata Wu & van Achterberg, sp. n. from China, and P. spectabilis van Achterberg, sp. n. from Japan. Coeloreuteus formosanus Watanabe, 1934, Opius (Lissosema proclivis Papp, 1981, O. (Psyttalia subcyclogaster Tobias, 1998, O. (P. darasunicus Tobias, 1998, O. (P. cyclogastroides Tobias, 1998, Psyttalia extensa Weng & Chen, 2001, and Rhogadopsis longicaudifera Li & van Achterberg, 2013, are new synonyms of Psyttalia cyclogaster (Thomson, 1895; Opius (Psyttalia ophthalmicus Tobias, 1977, and O. (P. brevitemporalis Tobias, 1998, of Psyttalia carinata (Thomson, 1895 and both O. (P. vacuus Tobias, 1998, and O. (Lissosema longurius Chen & Weng, 1995, of Rhogadopsis mediocarinata (Fischer, 1963. Phaedrotoma daghestanicum (Telenga, 1950, Rhogadopsis mediocarinata (Fischer, 1963 and R. mystica (Fischer, 1963 are new combinations. New records are Psyttalia carinata (Thomson, 1895 from The Netherlands and Norway, and P. cyclogaster (Thomson, 1895 from Japan. A lectotype is designated for Psyttalia carinata (Thomson, 1895 and P. cyclogaster (Thomson, 1895. A key to the East Palaearctic and North Oriental species of the genus Psyttalia Walker is included.

  17. Quantum gravity unification via transfinite arithmetic and geometrical averaging

    International Nuclear Information System (INIS)

    El Naschie, M.S.

    2008-01-01

    In E-Infinity theory, we have not only infinitely many dimensions but also infinitely many fundamental forces. However, due to the hierarchical structure of ε (∞) spacetime we have a finite expectation number for its dimensionality and likewise a finite expectation number for the corresponding interactions. Starting from the preceding fundamental principles and using the experimental findings as well as the theoretical value of the coupling constants of the electroweak and the strong forces we present an extremely simple averaging procedure for determining the quantum gravity unification coupling constant with and without super symmetry. The work draws heavily on previous results, in particular a paper, by the Slovian Prof. Marek-Crnjac [Marek-Crnjac L. On the unification of all fundamental forces in a fundamentally fuzzy Cantorian ε (∞) manifold and high energy physics. Chaos, Solitons and Fractals 2004;4:657-68

  18. The influence of atypical antipsychotic drugs on sexual function

    OpenAIRE

    Just, Marek J

    2015-01-01

    Marek J Just Department of General and Endocrine Surgery, Piekary Medical Centre, Piekary Slaskie, Poland Abstract: Human sexuality is contingent upon many biological and psychological factors. Such factors include sexual drive (libido), physiological arousal (lubrication/erection), orgasm, and ejaculation, as well as maintaining normal menstrual cycle. The assessment of sexual dysfunction can be difficult due to the intimate nature of the problem and patients’ unwillingness to di...

  19. Information about Editor-in-Chief and the Secretary of the International Scholarly Board of "Religious and Sacred Poetry"

    OpenAIRE

    Tytko, Marek Mariusz

    2014-01-01

    Tekst jest informacją biograficzną o dr. Marku Mariuszu Tytko, redaktorze naczelnym i sekretarzu Międzynarodowej Rady Naukowej "Religious and Sacred Poetry : An International Quarterly of Religion, Culture and Education". The text is the biographical information on Marek Mariusz Tytko, PhD, EDitor-in-Chief and secretary of the International Scholarly Council of "Religious and Sacred Poetry : An International Quarterly of Religion, Culture and Education".

  20. The Era of Global Disputes and Mass Media Distortions. Dialogue on Recognition, Justice and Democracy

    Czech Academy of Sciences Publication Activity Database

    Bittar, E.; Hrubec, Marek

    2017-01-01

    Roč. 8, č. 2 (2017), s. 146-154 ISSN 1338-130X Grant - others:AV ČR(CZ) StrategieAV21/15 Program:StrategieAV Institutional support: RVO:67985955 Keywords : global conflicts * international law * justice * mass media * recognition * democracy Subject RIV: AA - Philosophy ; Religion OBOR OECD: Political science https://www.communicationtoday.sk/era-global-disputes-mass-media-distortions-dialogue-recognition-justice-democracy-interview-marek-hrubec/

  1. Strandbergi imekangas tootmiseks valmis / Kaur Maran

    Index Scriptorium Estoniae

    Maran, Kaur

    2017-01-01

    Materjaliteadlased Marek Strandeberg ja Katrin Idla leiutasid kanga, millelt pinnalt radari välja kiiratud elektromagnetlained ei peegeldu tagasi ja kaitsevad nii objekte avastamise eest. Kanga eesmärgiks on muuta lennuk, tank või võitleja vaenlase radarile nähtamatuks. Senised katsetused on olnud edukad ning nüüd loodetakse kaitseministeeriumi hinnangut ja võimalikke tellimusi

  2. "Navigaator Prix" - 30 aastat hiljem / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2008-01-01

    Haapsalu õudusfilmide festivalile HÕFF on kutsutud poola režissöör Marek Piestrak, kes lavastas Stanislaw Lemi teose järgi Poola ja Tallinnfilmi ühistööna ulmefilmi "Navigaator Prix" (1978). Filmimuusika lõi Arvo Pärt, kandvas osas mängis kaasa Tõnu Saar. Lisatud andmeid režissööri kohta

  3. Annual Reports of Education, Health and Sport 9781329876002

    OpenAIRE

    Radzimińska, Agnieszka et al.

    2013-01-01

    Radomska Szkoła Wyższa w Radomiu Radom University in Radom Annual Reports of Education, Health and Sport 9781329876002 Edited by Iwona Czerwińska Pawluk Radosław Muszkieta Marek Napierała Walery Zukow http://ojs.ukw.edu.pl/index.php/johs/index www.journal.rsw.edu.pl https://pbn.nauka.gov.pl/search?search&searchCategory=WORK&filter.inJournal=49068 https://pbn....

  4. Tuumaenergiat tuleb Eestil oodata veel aastakümneid / Endel Lippmaa ; interv. Tanel Raig

    Index Scriptorium Estoniae

    Lippmaa, Endel, 1930-2015

    2008-01-01

    Akadeemiku arvates põhineb Eesti energiatootmine järgmised 25 aastat jätkuvalt põlevkivitööstusel, tuuleenergia ja hüdroenergia osa jäävad väikeseks, tuumaenergiat hakatakse arendama tulevikus. Diagramm: Põhiosa elektrienergiast tuleb soojuselektrijaamadelt. Lisa: Eesti energiamajanduse rahuldamise vahendid. Kommenteerib Riigikogu liige Marek Strandberg: talumaja peab muutuma oma energiavarustuselt sõltumatuks

  5. Levicový libertarianismus jako kritická teorie společnosti

    OpenAIRE

    Haimann, Tomáš

    2013-01-01

    Precis The Thesis comprehensively describes and explains basic concepts of Steiner-Vallentyne Left-Libertarianism. The introductory part compares this school of Left-Libertarianism with other approaches and advocates the method of critical theory of society being used, which was formulated by Marek Hrubec, successing classical authors of critical theory. This method divides the analyzed phenomena into three phases - critique, explanation and normativity. The critical phase describes relation ...

  6. Building on success / Edward Lucas

    Index Scriptorium Estoniae

    Lucas, Edward

    2007-01-01

    Eesti edust 1990ndatel aastatel. Kuid 2007. a. parlamendivalimised näitasid, et Eestis nagu teistes endistes kommunistlikes maades puudub reformialdis valitsus. Kiitust pälvib Eesti president Toomas Hendrik Ilves, kes pani veto pronkssõduri seadusele ja taunis Eesti iseseisvuspäeva pidustustel peetud kõnes korruptsiooni, enesega rahulolu ja takerdunud reforme. Vt. ka Marek Laane tõlge eesti keelde: Eesti vajab terasemat valitsust. Postimees 8. märts 2007, lk. 16

  7. Diplomatic Protection

    OpenAIRE

    Režná, Jana

    2006-01-01

    Final thesis Topic: Diplomatic protection Thesis supervisor: JUDr. Vladimír Balaš, CSc. Student: Marek Čermák Thesis on the topic of diplomatic protection deals with the granting of exercise of diplomatic protection by the states and is divided into seven chapters which follow each other. The first chapter describes the diplomatic protection and its historical foundations. The second chapter focuses on the possibility of exercise of diplomatic protection in respect of natural persons and the ...

  8. Two diagnoses become one? Rare case report of anorexia nervosa and Cushing?s syndrome

    OpenAIRE

    Sawicka, Nadia; Gryczy?ska, Maria; Sowi?ski, Jerzy; Tamborska-Zedlewska, Monika; Rucha?a, Marek

    2013-01-01

    Nadia Sawicka,* Maria Gryczyńska,* Jerzy Sowiński, Monika Tamborska-Zedlewska, Marek Ruchała Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland*These authors contributed equally to this workAbstract: Hypothalamic-pituitary-adrenal axis impairment in anorexia nervosa is marked by hypercortisolemia, and psychiatric disorders occur in the majority of patients with Cushing’s syndrome. Here we report a patient diagnosed...

  9. Kuidas üheskoos ajalugu mäletada? / Taavi Arus

    Index Scriptorium Estoniae

    Arus, Taavi

    2007-01-01

    Tallinna Ülikoolis 26. ja 27. juulil toimuvast loengusarjast, kus astuvad loengutega üles ajaloolased Peter Burke, Leonidas Donskis ja Maurice Bloch. Tallinna Ülikooli rektori professor Rein Raua sõnul on nimetatud loengusari üks selle suve intellektuaalseid kõrghetki. Loengutele järgnevad arutelud, mida juhivad vastavalt Tallinna Ülikooli Eesti Humanitaarinstituudi lektor Marek Tamm, filosoofiaprofessor Tõnu Viik ning antropoloogiadotsent Lorenzo Canas

  10. A Sixty-Year Timeline of the Air Force Maui Optical and Supercomputing Site

    Science.gov (United States)

    2013-01-01

    Physics conducts a site survey study near the summit of Haleakala to determine the suitability of the location for a solar observatory. Construction...Marek, 2001 1985 AMOS images shuttle to look for missing tiles . This is the first ever anomaly resolution using resolved imagery. Public Good...support an 8-m telescope base. The rest of the facility (azimuth base and mounting ring, azimuth yoke base, inner gimbal, dome roof , and walls) was

  11. Eestlaste arvutikeemia säästab miljoneid dollareid = Estonians' computational chemistry could save millions of dollars / Madli Kents

    Index Scriptorium Estoniae

    Kents, Madli

    2006-01-01

    Vt. ka Life in Estonia 2006/Spring, lk. 40-41. Keemik Mati Karelson on viimased 15 aastat tegelnud keemiliste ühendite omaduste ennustamisega arvuti abil. Koostöös Florida ülikooli teadlaste ja oma endiste tudengitega valmis arvutiprogramm Codessa, mis võimaldab eri keemiatoodete, sh ka ravimite testimiseks ja väljatöötamiseks kuluvat aega mitu korda vähendada. Kommenteerib Marek Strandberg

  12. Tänukiri

    Index Scriptorium Estoniae

    2000-01-01

    Tulemusliku töö eest tänukirjaga autasustatud TPÜ töötajad ja külalislektorid: Angela Arraste, Cécile Eliziere, Margus Harak, Aili Kants, Edgar Karofeld, Aili Kelam, Wolf Peter Klein, Jüri Kruusvall, Marek Kuzmin, Viivi Maanso, Avo Petrauts, Anne Rooste, Helve Siivo, Leida Talts, Aili Tamm, Anu Toots, Ülo Ugaste, Urve Väljas, Paul Ruudi / allikas : TPÜ rektori käskkiri, 13. oktoober 2000

  13. The ordered network structure and its prediction for the big floods of the Changjiang River Basins

    Energy Technology Data Exchange (ETDEWEB)

    Men, Ke-Pei; Zhao, Kai; Zhu, Shu-Dan [Nanjing Univ. of Information Science and Technology, Nanjing (China). College of Mathematics and Statistics

    2013-12-15

    According to the latest statistical data of hydrology, a total of 21 floods took place over the Changjiang (Yangtze) River Basins from 1827 to 2012 and showed an obvious commensurable orderliness. In the guidance of the information forecasting theory of Wen-Bo Weng, based on previous research results, combining ordered analysis with complex network technology, we focus on the summary of the ordered network structure of the Changjiang floods, supplement new information, further optimize networks, construct the 2D- and 3D-ordered network structure and make prediction research. Predictions show that the future big deluges will probably occur over the Changjiang River Basin around 2013-2014, 2020-2021, 2030, 2036, 2051, and 2058. (orig.)

  14. The ordered network structure and its prediction for the big floods of the Changjiang River Basins

    International Nuclear Information System (INIS)

    Men, Ke-Pei; Zhao, Kai; Zhu, Shu-Dan

    2013-01-01

    According to the latest statistical data of hydrology, a total of 21 floods took place over the Changjiang (Yangtze) River Basins from 1827 to 2012 and showed an obvious commensurable orderliness. In the guidance of the information forecasting theory of Wen-Bo Weng, based on previous research results, combining ordered analysis with complex network technology, we focus on the summary of the ordered network structure of the Changjiang floods, supplement new information, further optimize networks, construct the 2D- and 3D-ordered network structure and make prediction research. Predictions show that the future big deluges will probably occur over the Changjiang River Basin around 2013-2014, 2020-2021, 2030, 2036, 2051, and 2058. (orig.)

  15. Vägivald ja propaganda

    Index Scriptorium Estoniae

    2006-01-01

    8. IV-28. V Tallinna Kunstihoones Elin Kardi, Marco Laimre, Marko Mäetamme ja Andres Tali näitus "Vägivald ja propaganda". 26. IV-7. V näituse raames emergency biennale, rahvusvaheline rändnäitus Tšetšeenia toetuseks. 27. IV Kaasaegse Kunsti Eesti Keskuse IV ettekannete päev "Kunstniku moraalsed valikud liberaalse demokraatia ja islami kokkupõrgetes". Esinevad Margit Sutrop, Johannes Saar, Marek Järvik, Ene-Liis Semper & Eero Epner ning näitusel "Vägivald ja propaganda" osalevad kunstnikud

  16. "Poezja Religijna i Sakralna", nr 2

    OpenAIRE

    Tytko, Marek Mariusz

    2013-01-01

    Wstęp do "Religious and Sacred Poetry: An International Quarterly of Religion, Culture and Education" dotyczy głównie profilu czasopisma, jego struktury i zespołu autorskiego. Redaktor naczelny (Marek Mariusz Tytko) opisuje treść kwartalnika i jego program. Chrześcijańska kultura, religijna kultura literacka, chrześcijańska poezja religijna i poezja sakralna są głownym obszarem badawczym autorów tego kwartalnika. This introduction to Religious and Sacred Poetry: An International Quarterly ...

  17. Prefazione al quinto volume di GERBERTVS

    Science.gov (United States)

    Sigismondi, Costantino

    The act of the symposia dedicated to Gerbert of Aurillac in Rome on May 10, 2013 and May 12, 2014 are here published with contributions from Wojciech Janusiewicz on Gerbert and Poland, Flavio G. Nuvolone on Gerbert and Boethius, Gerbert and the violence, Marek Otisk on the use of Boethius Arithmetica in X century, Paolo Colona on the Poet Petrarca (XIV century) and Astronomy. Costantino Sigismondi contributes with several works dealing with history of astronomy and observational astronomy, especially the one of variable stars with naked eye, for the great didactical value of such observations.

  18. Vladimir Prelog i Zavod za organsku kemiju

    OpenAIRE

    Jakopčić, K.

    2007-01-01

    The Department of organic chemistry was founded on October 1st, 1922 as part of the Chemical Engineering Department of the High Technical School in Zagreb. The first-appointed professor of organic chemistry was Ivan Marek, formerly the professor at the School of Trade in Zagreb. The High Technical School with all its departments was soon (1926/27) incorporated into the University of Zagreb and became the nucleus of the Technical Faculty. The management of the faculty was fully aware of the ne...

  19. Colloid and surface chemistry a laboratory guide for exploration of the nano world

    CERN Document Server

    Bucak, Seyda

    2013-01-01

    Scientific Research The research processEthics in Science Design of Experiments Fundamentals of Scientific Computing, Nihat Baysal Recording Data: Keeping a Good Notebook Presenting Data: Writing a Laboratory ReportReferencesCharacterization Techniques Surface Tension Measurements, Seyda BucakViscosity/Rheological Measurements, Patrick UnderhillElectrokinetic Techniques, Marek KosmulskiDiffraction (XRD), Deniz RendeScattering, Ulf OlssonMicroscopy, Cem Levent Altan and Nico A.J.M. SommerdijkColloids and Surfaces Experiment 1: SedimentationExperiment 2: Determination of Critical Micelle Concent

  20. Cechy somatyczne i sprawność dzieci i młodzieży z wybranych szkół regionu bydgoskiego = Somatic features and efficiency of children and youth from the selected school of Bydgoszcz region

    OpenAIRE

    Wierzbowski, Łukasz Piotr et al.

    2017-01-01

    Napierała Marek Red., Zukow Walery Red. (2017). Cechy somatyczne i sprawność dzieci i młodzieży z wybranych szkół regionu bydgoskiego = Somatic features and efficiency of children and youth from the selected school of Bydgoszcz region. RSW. Radom. 160 s. ISBN 9781387327102 DOI http://dx.doi.org/10.5281/zenodo.1039563 PBN Poland https://pbn.nauka.gov.pl/sedno-webapp/works/835498 Radomska Szkoła Wyższa w Radomiu ...

  1. On the number of elementary particles in a resolution dependent fractal spacetime

    International Nuclear Information System (INIS)

    He Jihuan

    2007-01-01

    We reconsider the fundamental question regarding the number of elementary particles in a minimally extended standard model. The main conclusion is that since the dimension of E-infinity spacetime is resolution dependent, then the number of elementary particles is also resolution dependent. For D = 10 of superstrings, D = 11 of M theory and D = 12 of F theory one finds N(SM) equal to (6)(10) = 60 (6)(11) = 66 and (6)(12) = 72 particles, respectively. This is in perfect agreement with prediction made previously by Mohamed Saladin El-Naschie and Marek-Crnjac

  2. „Ósmy dzień tygodnia”

    OpenAIRE

    Anna Zawadzka

    2012-01-01

    “The Eighth Day of the Week” The Eighth Day of the Week is a short story by Marek Hłasko revolving around the topic of losing virginity. Literary scholars consider Hłasko as a representative of machismo; a masculine and male-centred narrator. This text analyses and deconstructs the short story defending it as a comprehensive record of misogynist culture written from the perspective of the main female protagonist and not the expression of misogyny of the author himself. The tools of discou...

  3. Presidents' green rhetoric at U.N. questioned / Joel Alas

    Index Scriptorium Estoniae

    Alas, Joel

    2007-01-01

    President Toomas Hendrik Ilves kõneles 24. septembril 2007 ÜRO peakorteris toimunud kliimakonverentsil, tehes seda Euroopa Liidu eesistujamaa Portugali palvel kogu Euroopa Liidu nimel. Erakonna Eestimaa Rohelised liider Marek Strandberg seab kahtluse alla mõnede president T.H. Ilvese poolt esitatud väidete paikapidavuse. Leedu presidendi Valdas Adamkuse ja Läti presidendi Valdis Zatlersi poolt väljendatud seisukohtadest. Vabariigi President töövisiidil Ameerika Ühendriikides 20.-26.09.2007

  4. Aeg on Soome ja Rootsi töösturid kinni püüda / Taivo Paju, Kärt Blumberg

    Index Scriptorium Estoniae

    Paju, Taivo, 1968-

    2008-01-01

    Ettevõtete edutegurite üle arutlevad Arengufondi juhatuse liige Heido Vitsur, Balti Uuringute Instituudi juhatuse esimees Marek Tiits, TTÜ mehhaanikateaduskonna professor Rein Küttner. Vt. samas: Ketlin Priilinn. Metsikult kallis küll, kuid seda väärt; Merike Teder. Uute seadmeteta oleksime kadunud (ilmunud ka Molodjozh Estonii : Biznes Sreda 16. apr. lk. 8); Taivo Paju. Pelmeenikuningas Ivan Zakotei (ilmunud ka Molodjozh Estonii : Biznes Sreda 30. apr. lk. 11); Poolteist kuud ja tehas töökorras

  5. LHC gets the ball rolling

    CERN Multimedia

    2007-01-01

    1. The multidisciplinary team responsible for the RF ball project to check the interconnections. From left to right: Rhodri Jones (AB/BI), Eva Calvo (AB/BI), Francesco Bertinelli (AT/MCS), Sonia Bartolome Jimenez (TS/IC), Sylvain Weisz (TS/IC), Paul Cruikshank (AT/VAC), Willemjan Maan (AT/VAC), Alain Poncet (AT/MCS), Marek Gasior (AB/BI).2. During the tests the ball is inserted very carefully into the vacuum chamber.1. Le groupe pluridisciplinaire qui a mené le projet de balle RF pour vérifier les interconnexions avec, de gauche à droite, Rhodri Jones (AB/BI), Eva Calvo (AB/BI), Francesco Bertinelli (AT/MCS), Sonia Bartolome Jimenez (TS/IC), Sylvain Weisz (TS/IC), Paul Cruikshank (AT/VAC), Willemjan Maan (AT/VAC), Alain Poncet (AT/MCS) et Marek Gasior (AB/BI).2. Lors des tests, la balle est insérée dans la chambre à vide avec beaucoup de précaution.

  6. Diverse uses of feathers with emphasis on diagnosis of avian viral infections and vaccine virus monitoring

    Directory of Open Access Journals (Sweden)

    I Davidson

    2009-09-01

    Full Text Available The large amounts of feathers produced by the poultry industry, that is considered as a waste was explored for possible uses in various industries, such as meals for animals, biofuels, biodegradable plastic materials, combating water pollution and more. That review mentions these uses, but concentrate on the utilization of feathers for the diagnosis of viral infections and for monitoring vaccine viruses in chickens after vaccination. The viral diseases in which diagnosis using nucleic acids extracted from the feather shafts was described are, Marek's disease virus, circoviruses, chicken anemia virus, fowlpox virus, avian retroviruses, avian influenza virus and infectious laryngotracheitis virus. In two cases, of Marek's disease virus and of infectious laryngotracheitis virus, the differentiation of vaccine and wild-type viruses from feather shafts was made possible, thus allowing for monitoring the vaccination efficacy. The present review demonstrates also the stability of DNA viruses in feather shafts, and the possible evaluation of environmental dissemination of pathogens. When viruses are transmitted vertically, like in the cases of the retrovirus REV, a teratogenic effect on the development of feathers of the day-old newly hatched chick might occur in the case of avian influenza and the chicken anemia virus, which might indicate on a viral infection.

  7. [Role of vaccination in animal health].

    Science.gov (United States)

    Pastoret, Paul-Pierre

    2012-03-01

    According to the IFAH, veterinary vaccines currently account for 26% of the global market in veterinary medicines, reflecting the importance of vaccines in animal health, as well as the number of wild and domesticated target species, and the monospecific nature of most vaccines. Multispecies vaccines include tetanus and rabies. In 2010, the number of food-producing animals was estimated to be roughly 20 billion and is rising gradually. Fowl currently represent the main food species. Veterinary vaccination has allowed the eradication of rinderpest, as officially declared last year (2011), jointly by the World Organisation for Animal Health (OIE) and the Food and Agriculture Organisation of the United Nations (FAO). Rinderpest was a real scourge, and was only the second viral disease to be totally eradicated (after human smallpox). One characteristic of veterinary vaccination is the DIVA approach, "differentiating infected from vaccinated animals". The DIVA strategy is especially interesting for regulated control of diseases like foot-and-mouth disease, infectious bovine rhinotracheitis, pseudorabies, and classical swine fever. DIVA vaccination requires prior serological testing. Vaccination is also used for wild animals such as foxes (rabies) and wild boars (classical swine fever). "In ovo" vaccination of fowl on day 18 of the incubation period is used to prevent Marek's disease for instance, and double vaccination (vector and insert) to prevent both Marek's disease and Gumboro's disease in fowl. Animal vaccination can also help to protect human health, as illustrated by fowl vaccination against salmonellosis.

  8. Community Radiative Transfer Model for Inter-Satellites Calibration and Verification

    Science.gov (United States)

    Liu, Q.; Nalli, N. R.; Ignatov, A.; Garrett, K.; Chen, Y.; Weng, F.; Boukabara, S. A.; van Delst, P. F.; Groff, D. N.; Collard, A.; Joseph, E.; Morris, V. R.; Minnett, P. J.

    2014-12-01

    Developed at the Joint Center for Satellite Data Assimilation, the Community Radiative Transfer Model (CRTM) [1], operationally supports satellite radiance assimilation for weather forecasting. The CRTM also supports JPSS/NPP and GOES-R missions [2] for instrument calibration, validation, monitoring long-term trending, and satellite retrieved products [3]. The CRTM is used daily at the NOAA NCEP to quantify the biases and standard deviations between radiance simulations and satellite radiance measurements in a time series and angular dependency. The purposes of monitoring the data assimilation system are to ensure the proper performance of the assimilation system and to diagnose problems with the system for future improvements. The CRTM is a very useful tool for cross-sensor verifications. Using the double difference method, it can remove the biases caused by slight differences in spectral response and geometric angles between measurements of the two instruments. The CRTM is particularly useful to reduce the difference between instruments for climate studies [4]. In this study, we will carry out the assessment of the Suomi National Polar-orbiting Partnership (SNPP) [5] Cross-track Infrared Sounder (CrIS) data [6], Advanced Technology Microwave Sounder (ATMS) data, and data for Visible Infrared Imaging Radiometer Suite (VIIRS) [7][8] thermal emissive bands. We use dedicated radiosondes and surface data acquired from NOAA Aerosols and Ocean Science Expeditions (AEROSE) [9]. The high quality radiosondes were launched when Suomi NPP flew over NOAA Ship Ronald H. Brown situated in the tropical Atlantic Ocean. The atmospheric data include profiles of temperature, water vapor, and ozone, as well as total aerosol optical depths. The surface data includes air temperature and humidity at 2 meters, skin temperature (Marine Atmospheric Emitted Radiance Interferometer, M-AERI [10]), surface temperature, and surface wind vector. [1] Liu, Q., and F. Weng, 2006: JAS [2] Liu, Q

  9. Networks of ultra-fine Ag nanocrystals in a Teflon AF (registered) matrix by vapour phase e-beam-assisted deposition

    International Nuclear Information System (INIS)

    Biswas, A; Bayer, I S; Marken, B; Pounds, T D; Norton, M G

    2007-01-01

    We have fabricated nanocomposite thin films comprising silver (Ag) nanoparticles dispersed in a Teflon AF (registered) polymer matrix using electron-beam-assisted physical vapour deposition. Four different Ag nanoparticle volume fillings (20%, 35%, 70% and 75%) were achieved by varying the relative metal-polymer evaporation rates with the formation of highly crystalline Ag nanoparticles regardless of the filling ratio. The present fabrication technique allowed full control over dispersion uniformity of nanoparticles in the polymer network. At 20% and 35% metal volume fillings, the nanocomposite film morphology consists of a uniformly dispersed assembly of equiaxed isolated Ag nanoparticles. At higher metal volume fractions the nanocomposite structures displayed two different and unique Ag nanoparticle arrangements within the polymer matrix. In particular, at 70% metal filling, the formation of irregularly shaped clusters of individually assembled nanocrystals was observed. At a slightly higher volume filling (75%), larger irregularly shaped Ag nanocrystals that appeared to be the result of coalescence and grain growth were observed. Finally, a composite theory developed by Tandon and Weng was used to estimate various elastic properties of the nanocomposite films. At high metal filling, the reinforcing effect of the Ag nanoparticles was reflected as approximately a sixfold increase in the elastic modulus compared to the virgin polymer film. Possible applications of such ultra-fine metal nanoparticles networks are discussed

  10. Microstructural characterisation and change in a.c. magnetic susceptibility of duplex stainless steel during spinodal decomposition

    Energy Technology Data Exchange (ETDEWEB)

    Lo, K.H., E-mail: KHLO@umac.m [Department of Electromechanical Engineering, University of Macau, Macau (China); Department of Physics and Materials Science, City University of Hong Kong (Hong Kong); Lai, J.K.L. [Department of Physics and Materials Science, City University of Hong Kong (Hong Kong)

    2010-06-15

    The microstructural changes during long-term (up to 10,000 h) spinodal decomposition in a duplex stain less steel, 7MoPLUS, have been characterised using TEM, a.c. magnetic susceptibility, X-ray diffractometry, microhardness measurement and optical microscopy. The microstructural changes and deformation microstructures of ferrite and austenite upon spinodal decomposition are characterised. The use of a.c. magnetic susceptibility to study the progress of spinodal decomposition is discussed. Above 450 {sup o}C, recent research by K.L. Weng et al. Mater. Sci. Eng. A 379 (2004) 119 has established that spinodal decomposition leads to crisscrossing of dislocations and the development of mottled contrast in the ferrite phase. The present work has shown that at 350 {sup o}C (the low-end of the spinodal range), crisscrossing of dislocations still occurs, but mottled contrast is absent. The G phase tends to be in contact with dislocations and its precipitation lags behind the occurrence of spinodal decomposition. No noticeable microstructural changes could be observed in the austenite phase in the spinodal temperature regime.

  11. Nanostructured magnesium has fewer detrimental effects on osteoblast function

    Directory of Open Access Journals (Sweden)

    Weng L

    2013-05-01

    Full Text Available Lucy Weng, Thomas J Webster School of Engineering and Department of Orthopedics, Brown University, Providence, RI, USA Abstract: Efforts have been made recently to implement nanoscale surface features on magnesium, a biodegradable metal, to increase bone formation. Compared with normal magnesium, nanostructured magnesium has unique characteristics, including increased grain boundary properties, surface to volume ratio, surface roughness, and surface energy, which may influence the initial adsorption of proteins known to promote the function of osteoblasts (bone-forming cells. Previous studies have shown that one way to increase nanosurface roughness on magnesium is to soak the metal in NaOH. However, it has not been determined if degradation of magnesium is altered by creating nanoscale features on its surface to influence osteoblast density. The aim of the present in vitro study was to determine the influence of degradation of nanostructured magnesium, created by soaking in NaOH, on osteoblast density. Our results showed a less detrimental effect of magnesium degradation on osteoblast density when magnesium was treated with NaOH to create nanoscale surface features. The detrimental degradation products of magnesium are of significant concern when considering use of magnesium as an orthopedic implant material, and this study identified a surface treatment, ie, soaking in NaOH to create nanoscale features for magnesium that can improve its use in numerous orthopedic applications. Keywords: nanostructured magnesium, degradation, detrimental effects, osteoblasts

  12. The ordered network structure of M {>=} 6 strong earthquakes and its prediction in the Jiangsu-South Yellow Sea region

    Energy Technology Data Exchange (ETDEWEB)

    Men, Ke-Pei [Nanjing Univ. of Information Science and Technology (China). College of Mathematics and Statistics; Cui, Lei [California Univ., Santa Barbara, CA (United States). Applied Probability and Statistics Dept.

    2013-05-15

    The the Jiangsu-South Yellow Sea region is one of the key seismic monitoring defence areas in the eastern part of China. Since 1846, M {>=} 6 strong earthquakes have showed an obvious commensurability and orderliness in this region. The main orderly values are 74 {proportional_to} 75 a, 57 {proportional_to} 58 a, 11 {proportional_to} 12 a, and 5 {proportional_to} 6 a, wherein 74 {proportional_to} 75 a and 57 {proportional_to} 58 a with an outstanding predictive role. According to the information prediction theory of Wen-Bo Weng, we conceived the M {>=} 6 strong earthquake ordered network structure in the South Yellow Sea and the whole region. Based on this, we analyzed and discussed the variation of seismicity in detail and also made a trend prediction of M {>=} 6 strong earthquakes in the future. The results showed that since 1998 it has entered into a new quiet episode which may continue until about 2042; and the first M {>=} 6 strong earthquake in the next active episode will probably occur in 2053 pre and post, with the location likely in the sea area of the South Yellow Sea; also, the second and the third ones or strong earthquake swarm in the future will probably occur in 2058 and 2070 pre and post. (orig.)

  13. A boost to visits

    CERN Multimedia

    2005-01-01

    Several guides were rewarded by CERN's Director-General and Secretary-General for their contributions in 2004. Left to right: Géraldine Chuste, the Director-General Robert Aymar, Klaus Batzner, Philippe Moret, Joanna Weng, Alberto Ribon, Head of the Visits Service, Emma Sanders, and the Secretary-General, Maximilian Metzger. Three other guides not in the photograph, Antonio Francano, Christoph Ilgner and Tzanko Spassoff, were also rewarded for their contributions. As every year, the CERN Visits Service has paid tribute to its guides, all of whom are volunteers and devote some of their time to showing people around their Laboratory. The guides were invited to a get-together in Microcosm during which the Director-General, Robert Aymar, expressed his special gratitude for their efforts and presented awards to the most dedicated among them. He encouraged members of the Laboratory to become guides and underlined that 2004 had been an exceptional year for visits, which had risen by 15% to almost 22,000. Including ...

  14. Analytical modeling of effect of interlayer on effective moduli of layered graphene-polymer nanocomposites

    Institute of Scientific and Technical Information of China (English)

    C.C.Roach; Y.C.Lu

    2017-01-01

    Nanocomposites enhanced with two-dimensional,layered graphene fillers are a new class of engineering materials that exhibit superior properties and characteristics to composites with conventional fillers.However,the roles of "interlayers" in layered graphene fillers have yet to be fully explored.This paper examines the effect of interlayers on mechanical properties of layered graphene polymer composites.As an effective filler,the fundamental properties (in-plane Young's modulus EL1,out-of-plane Young's modulus EL2;shear modulus GL12,major Poisson's ratio 1L12) of the layered graphene were computed by using the Arridge's lamellar model.The effects of interlayers on effective moduli of layered graphene epoxy composites were examined through the Tandon-Weng model.The properties of the interlayer show noticeable impact on elastic properties of the composites,particular the out-of-plane properties (Young's modulus E2 and shear modulus G12).The interlayer spacing is seen to have much great influence on properties of the composites.As the interlayer spacing increases from 0.34 nm to 2 nm,all elastic properties of the composites have been greatly decreased.

  15. What’s in the pipeline? Drugs in development for autism spectrum disorder

    Directory of Open Access Journals (Sweden)

    Sung M

    2014-02-01

    Full Text Available Min Sung,1 Chee Hon Chin,1 Choon Guan Lim,1 Hwee Sen Alvin Liew,1 Chau Sian Lim,2 Espérance Kashala,1 Shih-Jen Weng1 1Department of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore; 2Department of Psychological Medicine, Khoo Teck Puat Hospital, Singapore Abstract: Autism Spectrum Disorder (ASD is a complex neurodevelopmental disorder with both core symptoms and associated symptoms (eg, irritability, aggression, and comorbidities that affect both the individual and the family/systems around them. There have been recent advances in the understanding of the underlying pathophysiology of ASD pertaining to genetics, epigenetics, neurological, hormonal, and environmental factors that contribute to the difficulties found in individuals with ASD. With this improved understanding, there has been a shift in the application of psychopharmacology in ASD and its related disorders. A literature review was conducted to examine research published in the last 5 years between different classes of psychotropic medications and ASD. The broad scope of the existing literature for the use of conventional medications is summarized and novel medications are discussed. Keywords: pharmacology, treatment, autism, Asperger’s syndrome, medication

  16. Fiscal 1992 report on geothermal development promotion survey (Development of geothermal reservoir assessment technique); 1989 nendo chinetsu kaihatsu sokushin chosa (Chinetsu choryusou hyoka shuho kaihatsu hokokusho)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    Efforts were exerted in fiscal 1984-1992 to develop techniques for appropriately assessing a geothermal reservoir for its productivity for duly predicting the optimum scale of power generation to be provided thereby. In the development of simulators, geothermal reservoir simulators (SING-1, -2, -3) and a geothermal well 2-phase flow simulator (WENG) were developed. As for the treatment of fractures in a reservoir and of substances soluble in the hot water, the methods for dealing with them were improved and augmented. In a model field study in a Hokkaido forest, reservoir pressure continuous observation and monitoring, temperature logging and pressure logging for existing wells, and geothermal fluid chemical analysis were performed for reservoir analysis, in which both natural state simulation and history mapping excellently reproduced the temperature and pressure distributions. The temperature and pressure distributions in a natural state simulation, out of the results of an analysis of the Oguni district model field, Kumamoto Prefecture, agreed not only with those in the natural state but also with the pressure transition data in the observation well. (NEDO)

  17. Evidence of topological insulator state in the semimetal LaBi

    Science.gov (United States)

    Lou, R.; Fu, B.-B.; Xu, Q. N.; Guo, P.-J.; Kong, L.-Y.; Zeng, L.-K.; Ma, J.-Z.; Richard, P.; Fang, C.; Huang, Y.-B.; Sun, S.-S.; Wang, Q.; Wang, L.; Shi, Y.-G.; Lei, H. C.; Liu, K.; Weng, H. M.; Qian, T.; Ding, H.; Wang, S.-C.

    2017-03-01

    By employing angle-resolved photoemission spectroscopy combined with first-principles calculations, we performed a systematic investigation on the electronic structure of LaBi, which exhibits extremely large magnetoresistance (XMR), and is theoretically predicted to possess band anticrossing with nontrivial topological properties. Here, the observations of the Fermi-surface topology and band dispersions are similar to previous studies on LaSb [L.-K. Zeng, R. Lou, D.-S. Wu, Q. N. Xu, P.-J. Guo, L.-Y. Kong, Y.-G. Zhong, J.-Z. Ma, B.-B. Fu, P. Richard, P. Wang, G. T. Liu, L. Lu, Y.-B. Huang, C. Fang, S.-S. Sun, Q. Wang, L. Wang, Y.-G. Shi, H. M. Weng, H.-C. Lei, K. Liu, S.-C. Wang, T. Qian, J.-L. Luo, and H. Ding, Phys. Rev. Lett. 117, 127204 (2016), 10.1103/PhysRevLett.117.127204], a topologically trivial XMR semimetal, except the existence of a band inversion along the Γ -X direction, with one massless and one gapped Dirac-like surface state at the X and Γ points, respectively. The odd number of massless Dirac cones suggests that LaBi is analogous to the time-reversal Z2 nontrivial topological insulator. These findings open up a new series for exploring novel topological states and investigating their evolution from the perspective of topological phase transition within the family of rare-earth monopnictides.

  18. No evidence for surface organization in Kanizsa configurations during continuous flash suppression.

    Science.gov (United States)

    Moors, Pieter; Wagemans, Johan; van Ee, Raymond; de-Wit, Lee

    2016-04-01

    Does one need to be aware of a visual stimulus for it to be perceptually organized into a coherent whole? The answer to this question regarding the interplay between Gestalts and visual awareness remains unclear. Using interocular suppression as the paradigm for rendering stimuli invisible, conflicting evidence has been obtained as to whether the traditional Kanizsa surface is constructed during interocular suppression. While Sobel and Blake (2003) and Harris, Schwarzkopf, Song, Bahrami, and Rees (2011) failed to find evidence for this, Wang, Weng, and He (2012) showed that standard configurations of Kanizsa pacmen would break interocular suppression faster than their rotated counterparts. In the current study, we replicated the findings by Wang et al. (2012) but show that neither an account based on the construction of a surface nor one based on the long-range collinearities in the standard Kanizsa configuration stimulus could fully explain the difference in breakthrough times. We discuss these findings in the context of differences in the amplitudes of the Fourier orientation spectra for all stimulus types. Thus, we find no evidence that the integration of separate elements takes place during interocular suppression of Kanizsa stimuli, suggesting that this Gestalt involving figure-ground assignment is not constructed when rendered nonconscious using interocular suppression.

  19. A simple and rapid approach to develop recombinant avian herpesvirus vectored vaccines using CRISPR/Cas9 system.

    Science.gov (United States)

    Tang, Na; Zhang, Yaoyao; Pedrera, Miriam; Chang, Pengxiang; Baigent, Susan; Moffat, Katy; Shen, Zhiqiang; Nair, Venugopal; Yao, Yongxiu

    2018-01-29

    Herpesvirus of turkeys (HVT) has been successfully used as live vaccine against Marek's disease (MD) worldwide for more than 40 years either alone or in combination with other serotypes. HVT is also widely used as a vector platform for generation of recombinant vaccines against a number of avian diseases such as infectious bursal disease (IBD), Newcastle disease (ND) and avian influenza (AI) using conventional recombination methods or recombineering tools on cloned viral genomes. In the present study, we describe the application of CRISPR/Cas9-based genome editing as a rapid and efficient method of generating HVT recombinants expressing VP2 protein of IBDV. This approach offers an efficient method to introduce other viral antigens into the HVT genome for rapid development of recombinant vaccines. Copyright © 2018 The Pirbright Institute. Published by Elsevier Ltd.. All rights reserved.

  20. Franchising as a Way of Creating Entrepreneurship and Innovation

    Directory of Open Access Journals (Sweden)

    Lewandowska Lucyna

    2014-09-01

    Full Text Available Artykuł traktuje o franczyzie jako koncepcji prowadzenia działalności gospodarczej na podstawie uzgodnionego przez strony układu ekonomicznego. Dostarcza informacji o genezie franczyzy, uwarunkowaniach jej rozwoju w świecie i Polsce. Prezentuje udokumentowane tendencje wzrostu polskiego rynku franczyzowego z uwzględnieniem rodzimych i zagranicznych marek franczyzowych. Zwraca uwagę na atuty franczyzy pozwalające jej oprzeć się kryzysom gospodarczym, stymulować rozwój przedsiębiorczości i innowacyjności oraz minimalizować ryzyko biznesowe. Zawiera również komentarze, spostrzeżenia, sugestie i konstatacje na temat efektów synergicznych uzyskiwanych w firmach i całej polskiej gospodarce z tytułu zastosowań franczyzy.

  1. Measurement of Beam Tunes in the Tevatron Using the BBQ System

    International Nuclear Information System (INIS)

    Edstrom, Dean R.

    2009-01-01

    Measuring the betatron tunes in any synchrotron is of critical importance to ensuring the stability of beam in the synchrotron. The Base Band Tune, or BBQ, measurement system was developed by Marek Gasior of CERN and has been installed at Brookhaven and Fermilab as a part of the LHC Accelerator Research Program, or LARP. The BBQ was installed in the Tevatron to evaluate its effectiveness at reading proton and antiproton tunes at its flattop energy of 980 GeV. The primary objectives of this thesis are to examine the methods used to measure the tune using the BBQ tune measurement system, to incorporate the system into the Fermilab accelerator controls system, ACNET, and to compare the BBQ to existing tune measurement systems in the Tevatron

  2. Measurement of Beam Tunes in the Tevatron Using the BBQ System

    Energy Technology Data Exchange (ETDEWEB)

    Edstrom, Dean R.; /Indiana U.

    2009-04-01

    Measuring the betatron tunes in any synchrotron is of critical importance to ensuring the stability of beam in the synchrotron. The Base Band Tune, or BBQ, measurement system was developed by Marek Gasior of CERN and has been installed at Brookhaven and Fermilab as a part of the LHC Accelerator Research Program, or LARP. The BBQ was installed in the Tevatron to evaluate its effectiveness at reading proton and antiproton tunes at its flattop energy of 980 GeV. The primary objectives of this thesis are to examine the methods used to measure the tune using the BBQ tune measurement system, to incorporate the system into the Fermilab accelerator controls system, ACNET, and to compare the BBQ to existing tune measurement systems in the Tevatron.

  3. Clinical application and research of tumor markers in colorectal cancer

    International Nuclear Information System (INIS)

    Chen Yumei

    2005-01-01

    Colorectal cancer is one of the most common malignant tumors. There are many tumor markers for detecting colorectal cancer, some of which have been widely used in clinical area. However, still lack an ideal tumor marker of colorectal cancer. In this review, we simply characterized some common tumor markers including carcinoembryonic antigen, CA19-9, CA50, CA242 etc and their dignostic value. And here we discussed some combined detecting procedures which improve diagnostic accuracy of colorectal cancer. In addition, with the development of the biomoleculer technique, some newly discovered tumor markers and genetic marekers have gained great progress in the research of colorectal cancer, and will become a promissing technique in the diagnosis of colorectal cancer. (authors)

  4. „Rejs" jako gatunek

    Directory of Open Access Journals (Sweden)

    Marek Hendrykowski

    2007-06-01

    Full Text Available Marek Piwowski's film „Rejs" (The Cruise made in 1969 and the premiere of which was on 10 October 1970 at „Bajka" cinema in Warsaw, rightly (deserves to be one of the most popular Polish films of all time. This study attempts to offer a more complete characterisation of the feature of the genre of this unusual work of film art. It is commonly thought that „Rejs" is a comedy. Against the background of the model of comedy of the 60s of the 20th century, however, it is a comedy of a very special kind. The author does not doubt the comedic character of Piwowski's film, but points to different possible from those used until now ways of interpreting this film (a holiday comedy, anti-production film, social satire, pamphlet, psychodrama, sociodrama, starting from the assumption that the genre instruction written into this work contains a much richer repertoire of possible interpretations.

  5. Eesti kultuuri võimatu mõiste / Tõnu Viik

    Index Scriptorium Estoniae

    Viik, Tõnu, 1968-

    2012-01-01

    Millest lähtuda eesti kultuuri määretlemisel. Kuidas vaadelda eesti rahvuse seotust eesti kultuuri mõistega. Kultuurrahvusluse ideest. Eestis domineeriva kultuurrahvusluse osaks olevast poliitilisest alluvusnõudest. Slavoj Žižeki rahvusliku kultuuri määratlusest. "Sisevaenlase" kujundist, rahvusluse seotusest diktatuuri kehtestamise vajadusega. Autor on seisukohal, et sisuliselt ei ole võimalik eesti kultuuri kultuurrahvusluse kaudu määratleda. Mart Kivimäe, Raivo Vetiku, Jaan Kaplinski, Hasso Krulli, Märt Väljataga, Tiit Hennoste, Rein Veidemanni, Marek Tamme ja Peeter Toropi seisukohti. Eesti kultuurist kui enesekoloniseerimise kultuurist. Kaasaegse kultuuri ligitõmbavuse tekib tunne, et ta on piiranguteta lahti kogu maailmale

  6. Pathology of spontaneous tumour lesions in pullets and adult chickens in commercial farms - Short communication.

    Science.gov (United States)

    Ikezawa, Mitsutaka; Sasaki, Jun; Goryo, Masanobu

    2012-09-01

    Twenty pullets and adult chickens, aged 100 to 403 days, from several commercial chicken farms were examined by gross and histopathology. Grossly, all chickens had white-greyish masses in the visceral organs with or without enlargement of the peripheral nerves. Histopathological examination revealed Marek's disease (MD) lymphoma, lymphoid leukosis (LL) and myeloid leukosis (ML) in 14/20, 5/20 and 1/20 of the chickens, respectively. Lesions of the sciatic nerves in chickens diagnosed as having MD lymphoma were various. No neoplastic and/or inflammatory cells were noted in the peripheral nerves of chickens diagnosed as having LL and ML. These results indicated that MD lymphoma could also develop in older chickens; thus, microscopic examination is needed to identify MD in older chickens showing lymphocyte-derived tumours.

  7. Dicty_cDB: Contig-U04064-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ( FD686515 ) CBHX5739.rev CBHX Mycosphaerella fijiensis MfEST4... 38 0.068 2 ( FG292734 ) 1108770641730 New World... Screwworm Larvae 9387 EST... 38 0.069 3 ( FG293376 ) 1108770670007 New World Screwworm Larvae 9387 EST...... 38 0.069 3 ( FG292982 ) 1108770653482 New World Screwworm Larvae 9387 EST... 38 0.073 3 ( FG300950 ) 1108799246492 New World...05 Marek's disease virus-infected spleen... 40 2.4 2 ( FG294814 ) 1108770718996 New World...C... 32 2.6 2 ( EH523252 ) FDR107-P00037-DEPE-R_J20 FDR107 Danio rerio cDNA ... 36 2.7 2 ( FG300042 ) 1108793358690 New World

  8. Gombrowicz a polski film fabularny

    Directory of Open Access Journals (Sweden)

    Jacek Nowakowski

    2013-01-01

    Full Text Available This article presents the influence that Witold Gombrowicz’s work has had on Polish cinema. It covers several generations of directors, for example, Andrzej Munk (born in the 1920s, Roman Polański and Jerzy Skolimowski (born in the 1930 as well as Agnieszka Holland, Piotr Szulkin and Marek Koterski (born in the 1940s and 1950s, and discusses the topic of film adaptations of his books (Jerzy Skolimowski’s Ferdydurke and Jan Jakub Kolski’s Pornografia [Pornography]. The article shows that Polish cinema uses Gombrowicz’s works most of all by taking up the issue of life’s authenticity and inauthenticity as well as to demythologize Polish tradition and history. As for esthetics, it employs Gombrowicz’s favorite style, i.e. the grotesque.

  9. The non- -existent wall? The problem of describing Muranów

    Directory of Open Access Journals (Sweden)

    Beata Przymuszała

    2015-12-01

    Full Text Available The article presents the problem of recovering the memory of the Warsaw district of Muranów, the site of the WW2 ghetto in recent literature. Referring to one of the first works devoted to this subject (Jarosław Marek Rymkiewicz’s Umschlagplatz, the author reveals subsequent changes in the treatment Jacek Leociak, Beata Chomątowska and Elżbieta Janicka’s of the issue in their books. Indicating the oscillation between remembrance and forgetting about the ghetto, the authors adopt different perspectives to touch upon the ambiguous presence of the area's former inhabitants in the consciousness of today’s Varsovians. Their ways of focusing attention on this question may be termed a commemorative perspective, focused on the psychology of space and critical discourse. Though signaling the problem differently, the authors are united in emphasising the problems related to the Polish memory of the Warsaw ghetto.

  10. ISOLDE’s rarest isotopes

    CERN Multimedia

    Katarina Anthony

    2013-01-01

    The ISOLDE physics section (PH-SME-IS) has recently observed an unusual transformation… one that may well be a sign of things to come for CERN.   The ISOLDE PH team, from left to right: Jennifer Weterings (user support), Susanne Kreim (research fellow), Marek Pfützner* (scientific associate), Maria Garcia Borge (team leader), Elisa Rapisarda (research fellow) , Magdalena Kowalska (physics coordinator), Jan Kurcewicz* (applied fellow), Monika Stachura (future applied fellow). Not in the photo: Kara Lynch (PhD student). Although more and more women are going into the physical sciences, it’s no secret that it remains a male-dominated field. But over the past six months, the ISOLDE PH section has become an exception to this rule: with female physicists outnumbering their male colleagues 3 to 1. “We’re probably one of the few teams at CERN where the personnel is mostly female,” says Magdalena Kowalska, the ISOLDE Physics Coordinator. &am...

  11. Areeni aasta album. Isiklikud edetabelid

    Index Scriptorium Estoniae

    2003-01-01

    Areen jagas punkte heliplaatidele: 1. The Streets "Original Pirate Material" 2. Common "Electric Circus" 3. Flaming Lips "Yoshimi Battles The Pink Robots" 4. DJ Shadow "Private Press" 5. Peven Everett "Studio Confessions" 6. Andrew WK "I Get Wet" 7. Underworld "A Hundred Days Off" 8.-9. Felix Da Housecat "Kittenz and Thee Glitz" 10. X-Press 2 "Muzikizum" 11. The Music "The Music" 12.-13. The Datsuns "The Datsuns" 12. 13 Peshay "Fuzion" 14. High Contrast "True Colours" 15. Tallinn 73 meets Kalm "Autopiloot" 16. Koop "Waltz For Koop" 17.-18. Death In Vegas "Scorpio Rising" 17.-18. A "Hi-Fi-Serious" 19.-20. Arto Lindsay "Invoke" 19.-20. Akufen "My Way". Isiklikud edetabelid Tõnu Kaalepilt, Marek Kallinilt, Erkki Luukilt, Tõnis Kahult, Raul Saaremetsalt, Siim Nestorilt, Koit Raudsepalt, Erik Mornalt, Mart Juurelt ja Märt Milterilt

  12. Mesoporous Silica-Supported Metal Oxide-Promoted Rh Nanocatalyst for Selective Production of Ethanol from Syngas

    Energy Technology Data Exchange (ETDEWEB)

    Kraus, George

    2010-09-30

    The objective is to develop a process that will convert synthesis gas from coal into ethanol and then transform the ethanol into hydrogen. Principal investigators from Iowa State University include Dr. George Kraus, Dr. Victor Lin, Marek Pruski, and Dr. Robert Brown. Task 1 involves catalyst development and catalyst scale up. Mesoporous manganese silicate mixed oxide materials will be synthesized, characterized and evaluated. The first-and secondgeneration catalysts have been prepared and scaled up for use in Task 2. The construction of a high-pressure reactor system for producing synthetic liquid fuel from simulated synthesis gas stream has been completed as the first step in Task 2. Using the first- and second generation catalysts, the reactor has demonstrated the production of synthetic liquid fuel from a simulated synthesis gas stream.

  13. Mapping Global Urban Dynamics from Nighttime Lights - 1992 to 2012

    Science.gov (United States)

    Xie, Yanhua

    Accurate, up-to-date, and consistent information of urban extent is indispensable for numerous applications central to urban planning, ecosystem management, and environmental assessment and monitoring. However, current large-scale urban extent products are not uniform with respect to urban definition, spatial resolution, thematic representation, and temporal frequency. To fill this gap, this study proposed a method to update and backdate global urban extent from currently available urban maps by using nighttime light (NTL) as the main indicator. The method followed three steps: (1) exploring the spatiotemporal variation of NTL thresholds for mapping urban dynamics from NTL time series and developing an object-based thresholding method (i.e., NTL-OUT method, Xie & Weng, 2016b); (2) spatiotemporally enhancing time-series Defense Meteorological Satellite Program/Operational Linescan System (DMSP/OLS) NTL data for detecting broad-scale urban changes (Xie & Weng, 2017); and (3) detecting global urban dynamics during the period between 1992 and 2012 (i.e., 1992, 1997, 2002, 2007, and 2012) from enhanced OLS NTL time series by using the NTL-OUT method. The results show that global urban extent almost doubled during the period from 1992 to 2012, increasing from 0.52 million to 0.98 million km 2, which accounts for 0.39% and 0.72% of the total global land area, respectively. Regionally, the urbanization level varies by continent, with Europe being the most urbanized, followed by North America, Asia, South America, Africa, and Australia-Oceania. In 1992, the urban extent varied from only 0.1% of total continental land area in Australia-Oceania and Africa to 1.18% in Europe. While the proportion of urban extent in North America increased slightly from 1992 to 2002 (i.e., 0.07%), urban extent increased 0.1% for both Asia and South America. In 2012, over 0.7% of the total land was covered by the human built environment, with 0.2% in Africa and Australia-Oceania and around 0

  14. An oil production forecast for China considering economic limits

    International Nuclear Information System (INIS)

    Wang, Ke; Feng, Lianyong; Wang, Jianliang; Xiong, Yi; Tverberg, Gail E.

    2016-01-01

    In recent years, it has become apparent that oil prices may not rise endlessly. Unconventional oil is likely to be especially affected by low prices because it tends to be high-priced to extract. To estimate the impact prices might have on future Chinese oil production, we develop a model in which only future unconventional oil production is affected by price. We analyze three price scenarios: Stays Low, Best Estimate, and Ever-Rising Prices. In these scenarios, remaining Ultimate Recoverable Resources (URR) are estimated to be 10%, 50%, and 90% of remaining Technically Recoverable Resources, respectively. Since oil price can be expected to affect the shape of the extraction curve, we spread estimated URR to year using models that do not assume that future production will ultimately produce a symmetric Hubbert-type curve (Multi-Cycle Generalized Weng Model and Stochastic Resource-Constrained Growth Model). In the Best Estimate Scenario, China's oil production is expected to reach a maximum of 226.79 million tons in 2020. In the Ever-Rising Prices Scenario, China's maximum oil production occurs in 2023. In the Stays Low Scenario, maximum production has already been reached. - Highlights: • China's conventional oil reached a peak in 2010 and has begun to decline. • Unconventional oil production will be especially adversely affected by low prices. • Rising selling price of oil may lead to recession, bringing prices back down. • China's total oil supply appears likely to peak about 2020. • Likely oil production is less than Technically Recoverable Resources.

  15. Long-term safety evaluation of bimatoprost ophthalmic solution 0.03%: a pooled analysis of six double-masked, randomized, active-controlled clinical trials

    Directory of Open Access Journals (Sweden)

    Wirta D

    2011-06-01

    Full Text Available David Wirta1, Amanda M VanDenburgh2, Emily Weng3, Scott M Whitcup4, Sef Kurstjens5, Frederick C Beddingfield III4,61Private Practice, Newport Beach, CA, USA; 2Clinical Development, 3Biostatistics, 4Research and Development, 5Global Drug Development, Allergan, Inc, Irvine, CA, USA; 6Department of Medicine, Division of Dermatology, David Geffen School of Medicine, UCLA, Los Angeles, CA, USABackground: Bimatoprost ophthalmic solution 0.03% was approved in the US for reducing intraoccular pressure (IOP based on two double-masked, active-controlled clinical trials. Four additional long-term studies (≥ 12months were conducted; however, the aggregate safety profile of the six studies has not been reported.Methods: Adverse events (AEs were pooled from six double-masked, active-controlled, long-term clinical trials in which subjects received bimatoprost 0.03% once daily (QD or twice daily (BID as an eyedrop. AE terms were converted to MedDRA (V.11.0 Preferred Terms and analyzed.Results: In total, 1409 patients received more than one dose of bimatoprost 0.03% QD or BID. Most AEs were mild in severity and reported by 86.7% (QD and 94.8% (BID of subjects (≤ 12 months of treatment. AEs reported through month 12 (aggregate incidence of ≥ 5% were conjunctival hyperemia, increased eyelash growth, eye pruritus, periocular skin hyperpigmentation, eye irritation, dry eye, and hypertrichosis. AE onset was generally reported within four months of treatment. The cumulative incidence of common AEs in the QD treatment group at 24–48 months was similar to that measured at 12 months of treatment.Conclusion: Bimatoprost 0.03% has a favorable safety and tolerability profile as characterized by six long-term studies. Common AEs were due to the known pharmacological activity of bimatoprost and reversible with treatment cessation.Keywords: intraocular pressure, eyelids, pharmacology, clinical trial, medical treatment

  16. People and things. CERN Courier, Mar-Apr 1995, v. 35(2)

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    The article reports on achievements of various people, staff changes and position opportunities within the CERN organization and contains news updates on upcoming or past events: Khosrow Chadan, former director of Orsay's Laboratoire de Physique théorique et particules élémentaires has been nominated Chevalier of the Legion of Honour. R. Vinh Mau, main author of the 'Paris' nucleon-nucleon potential, has been nominated and promoted Officer of the French Ordre du Mérite. Tom Roser is Head of the Accelerator Division in the Alternating Gradient Synchrotron Department at Brookhaven, succeeding Bill Weng. We apologize for the unfortunate misprint in the December issue, page 27. Academician Moisei Alexandrovich Markov died on 1 October. Although basically a theorist, he made major contributions to the development and infrastructure of Russian experimental physics. After graduating from Moscow in 1930, he went on to join the new Lebedev Institute. His initial interests were in the problem of infinities in quantum field theory, carrying out pioneer work on the idea of nonlocality, a regular theme during his career. In the 1960s he turned to fundamental questions at the interface between particle physics and cosmology. With the advent of major accelerators in the post-war period, he was a staunch promoter of experiments at these machines, first for the Lebedev electron machine, and subsequently for the Dubna proton synchrotron. After milestone contributions to the study of weak interactions, he stressed the importance of underground or underwater detectors for cosmic rays and neutrinos, leading to the establishment of the Baksan neutrino observatory. From 1967-88, as head of the Nuclear Physics Department of the Academy of Sciences, he oversaw the establishment of major new projects, including the Moscow meson factory as well as Baksan, while continually providing new stimulation for the research community. For many years he was the USSR representative

  17. Exploration of natural product ingredients as inhibitors of human HMG-CoA reductase through structure-based virtual screening

    Directory of Open Access Journals (Sweden)

    Lin SH

    2015-06-01

    Full Text Available Shih-Hung Lin,1 Kao-Jean Huang,1,2 Ching-Feng Weng,1 David Shiuan1 1Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien, Taiwan, Republic of China; 2Development Center of Biotechnology, Taipei, Taiwan, Republic of China Abstract: Cholesterol plays an important role in living cells. However, a very high level of cholesterol may lead to atherosclerosis. HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A reductase is the key enzyme in the cholesterol biosynthesis pathway, and the statin-like drugs are inhibitors of human HMG-CoA reductase (hHMGR. The present study aimed to virtually screen for potential hHMGR inhibitors from natural product to discover hypolipidemic drug candidates with fewer side effects and lesser toxicities. We used the 3D structure 1HWK from the PDB (Protein Data Bank database of hHMGR as the target to screen for the strongly bound compounds from the traditional Chinese medicine database. Many interesting molecules including polyphenolic compounds, polisubstituted heterocyclics, and linear lipophilic alcohols were identified and their ADMET (absorption, disrtibution, metabolism, excretion, toxicity properties were predicted. Finally, four compounds were obtained for the in vitro validation experiments. The results indicated that curcumin and salvianolic acid C can effectively inhibit hHMGR, with IC50 (half maximal inhibitory concentration values of 4.3 µM and 8 µM, respectively. The present study also demonstrated the feasibility of discovering new drug candidates through structure-based virtual screening. Keywords: HMG-CoA reductase, virtual screening, curcumin, salvianolic acid C

  18. Heat-transfer-based detection of SNPs in the PAH gene of PKU patients

    Directory of Open Access Journals (Sweden)

    Vanden Bon N

    2014-03-01

    Full Text Available Natalie Vanden Bon,1 Bart van Grinsven,2 Mohammed Sharif Murib,2 Weng Siang Yeap,2 Ken Haenen,2,3 Ward De Ceuninck,2,3 Patrick Wagner,2,3 Marcel Ameloot,1 Veronique Vermeeren,1 Luc Michiels11Biomedical Research Institute, Hasselt University, Diepenbeek, Belgium; 2Institute for Materials Research, Hasselt University, Diepenbeek, Belgium; 3IMOMEC, Diepenbeek, BelgiumAbstract: Conventional neonatal diagnosis of phenylketonuria is based on the presence of abnormal levels of phenylalanine in the blood. However, for carrier detection and prenatal diagnosis, direct detection of disease-correlated mutations is needed. To speed up and simplify mutation screening in genes, new technologies are developed. In this study, a heat-transfer method is evaluated as a mutation-detection technology in entire exons of the phenylalanine hydroxylase (PAH gene. This method is based on the change in heat-transfer resistance (Rth upon thermal denaturation of dsDNA (double-stranded DNA on nanocrystalline diamond. First, ssDNA (single-stranded DNA fragments that span the size range of the PAH exons were successfully immobilized on nanocrystalline diamond. Next, it was studied whether an Rth change could be observed during the thermal denaturation of these DNA fragments after hybridization to their complementary counterpart. A clear Rth shift during the denaturation of exon 5, exon 9, and exon 12 dsDNA was observed, corresponding to lengths of up to 123 bp. Finally, Rth was shown to detect prevalent single-nucleotide polymorphisms, c.473G>A (R158Q, c.932T>C (p.L311P, and c.1222C>T (R408W, correlated with phenylketonuria, displaying an effect related to the different melting temperatures of homoduplexes and heteroduplexes.Keywords: mutation detection, heat-transfer resistance, melting temperature, nanocrystalline diamond, persistence length

  19. Photochemistry and photophysics of the amino and imino tautomers of 1-methylcytosine: tautomerisation as a side product of the radiationless decay.

    Science.gov (United States)

    Li, Quansong; Blancafort, Lluís

    2013-08-01

    The photochemistry and photophysics of the amino-oxo (AO) and imino-oxo (IO) tautomers of 1-methylcytosine are investigated with ab initio calculations, using the CASPT2//CASSCF approach. Our aim is to rationalize recent experimental results which show that the AO tautomer has an excited state lifetime of about 1 ps, similar to cytosine (J.-W. Ho, H.-C. Yen, W.-K. Chou, C.-N. Weng, L.-H. Cheng, H.-Q. Shi, S.-H. Lai and P.-Y. Cheng, J. Phys. Chem. A, 2011, 115, 8406-8418), and that irradiation with wavelengths shorter than 308 nm induces the AO→IO tautomerization (I. Reva, M. J. Nowak, L. Lapinski and R. Fausto, J. Phys. Chem. B, 2012, 116, 5703-5710). For the canonical AO tautomer we find two analogous decay mechanisms to those described previously for cytosine, involving a conical intersection of ethylenic type and one where the amino group is bent out of plane. Decay through these intersections provides an unreactive return path to the AO ground state species. More importantly, we have identified new decay paths that lead from the two intersections to the trans-IO tautomer, without a barrier. These paths provide the possibility of forming the IO tautomer, presumably in small yields, as a side product of the radiationless decay. Thus, we have established for the first time computationally the mechanism of the UV-induced tautomerization, which is compatible with the well-established decay mechanism for cytosine. For the IO tautomer, we also find a mechanism for the excited state interconversion of the cis and trans forms and for efficient radiationless decay through a conical intersection where the imino group is perpendicular to the ring and bent out of the plane. These results are likely to be valid also for cytosine.

  20. The ordered network structure and prediction summary for M ≥ 7 earthquakes in Xinjiang region of China

    International Nuclear Information System (INIS)

    Men, Ke-Pei; Zhao, Kai

    2014-01-01

    M ≥ 7 earthquakes have showed an obvious commensurability and orderliness in Xinjiang of China and its adjacent region since 1800. The main orderly values are 30 a x k (k = 1, 2, 3), 11 ∝ 12 a, 41 ∝ 43 a, 18 ∝ 19 a, and 5 ∝ 6 a. In the guidance of the information forecasting theory of Wen-Bo Weng, based on previous research results, combining ordered network structure analysis with complex network technology, we focus on the prediction summary of M ≥ 7 earthquakes by using the ordered network structure, and add new information to further optimize network, hence construct the 2D- and 3D-ordered network structure of M ≥ 7 earthquakes. In this paper, the network structure revealed fully the regularity of seismic activity of M ≥ 7 earthquakes in the study region during the past 210 years. Based on this, the Karakorum M7.1 earthquake in 1996, the M7.9 earthquake on the frontier of Russia, Mongol, and China in 2003, and two Yutian M7.3 earthquakes in 2008 and 2014 were predicted successfully. At the same time, a new prediction opinion is presented that the future two M ≥ 7 earthquakes will probably occur around 2019-2020 and 2025-2026 in this region. The results show that large earthquake occurred in defined region can be predicted. The method of ordered network structure analysis produces satisfactory results for the mid-and-long term prediction of M ≥ 7 earthquakes.

  1. A hydrogel biosensor for high selective and sensitive detection of amyloid-beta oligomers

    Directory of Open Access Journals (Sweden)

    Sun LP

    2018-02-01

    Full Text Available Liping Sun,1 Yong Zhong,1 Jie Gui,1 Xianwu Wang,1 Xiaorong Zhuang,2 Jian Weng1 1Key Laboratory of Biomedical Engineering of Fujian Province, Research Center of Biomedical Engineering of Xiamen, Department of Biomaterials, College of Materials, Xiamen University, 2Department of Neurology, The Affiliated Zhongshan Hospital of Xiamen University, Xiamen, People’s Republic of China Background: Alzheimer’s disease (AD is a neurodegenerative disorder characterized by progressive cognitive and memory impairment. It is the most common neurological disease that causes dementia. Soluble amyloid-beta oligomers (AβO in blood or cerebrospinal fluid (CSF are the pathogenic biomarker correlated with AD. Methods: A simple electrochemical biosensor using graphene oxide/gold nanoparticles (GNPs hydrogel electrode was developed in this study. Thiolated cellular prion protein (PrPC peptide probe was immobilized on GNPs of the hydrogel electrode to construct an AβO biosensor. Electrochemical impedance spectroscopy was utilized for AβO analysis. Results: The specific binding between AβO and PrPC probes on the hydrogel electrode resulted in an increase in the electron-transfer resistance. The biosensor showed high specificity and sensitivity for AβO detection. It could selectively differentiate AβO from amyloid-beta (Aβ monomers or fibrils. Meanwhile, it was highly sensitive to detect as low as 0.1 pM AβO in artificial CSF or blood plasma. The linear range for AβO detection is from 0.1 pM to 10 nM. Conclusion: This biosensor could be used as a cost-effective tool for early diagnosis of AD due to its high electrochemical performance and bionic structure. Keywords: Alzheimer’s disease, amyloid-beta oligomer, graphene, gold nanoparticles, biosensor

  2. Spatiotemporally enhancing time-series DMSP/OLS nighttime light imagery for assessing large-scale urban dynamics

    Science.gov (United States)

    Xie, Yanhua; Weng, Qihao

    2017-06-01

    Accurate, up-to-date, and consistent information of urban extents is vital for numerous applications central to urban planning, ecosystem management, and environmental assessment and monitoring. However, current large-scale urban extent products are not uniform with respect to definition, spatial resolution, temporal frequency, and thematic representation. This study aimed to enhance, spatiotemporally, time-series DMSP/OLS nighttime light (NTL) data for detecting large-scale urban changes. The enhanced NTL time series from 1992 to 2013 were firstly generated by implementing global inter-calibration, vegetation-based spatial adjustment, and urban archetype-based temporal modification. The dataset was then used for updating and backdating urban changes for the contiguous U.S.A. (CONUS) and China by using the Object-based Urban Thresholding method (i.e., NTL-OUT method, Xie and Weng, 2016b). The results showed that the updated urban extents were reasonably accurate, with city-scale RMSE (root mean square error) of 27 km2 and Kappa of 0.65 for CONUS, and 55 km2 and 0.59 for China, respectively. The backdated urban extents yielded similar accuracy, with RMSE of 23 km2 and Kappa of 0.63 in CONUS, while 60 km2 and 0.60 in China. The accuracy assessment further revealed that the spatial enhancement greatly improved the accuracy of urban updating and backdating by significantly reducing RMSE and slightly increasing Kappa values. The temporal enhancement also reduced RMSE, and improved the spatial consistency between estimated and reference urban extents. Although the utilization of enhanced NTL data successfully detected urban size change, relatively low locational accuracy of the detected urban changes was observed. It is suggested that the proposed methodology would be more effective for updating and backdating global urban maps if further fusion of NTL data with higher spatial resolution imagery was implemented.

  3. Urban heat island research from 1991 to 2015: a bibliometric analysis

    Science.gov (United States)

    Huang, Qunfang; Lu, Yuqi

    2018-02-01

    A bibliometric analysis based on the Science Citation Index-Expanded (SCI-Expanded) database from the Web of Science was performed to review urban heat island (UHI) research from 1991 to 2015 and statistically assess its developments, trends, and directions. In total, 1822 papers published in 352 journals over the past 25 years were analyzed for scientific output; citations; subject categories; major journals; outstanding keywords; and leading countries, institutions, authors, and research collaborations. The number of UHI-related publications has continuously increased since 1991. Meteorology atmospheric sciences, environmental sciences, and construction building technology were the three most frequent subject categories. Building and Environment, International Journal of Climatology, and Theoretical and Applied Climatology were the three most popular publishing journals. The USA and China were the two leading countries in UHI research, contributing 49.56% of the total articles. Chinese Academy of Science, Arizona State University, and China Meteorological Administration published the most UHI articles. Weng QH and Santamouris M were the two most prolific authors. Author keywords were classified into four major groups: (1) research methods and indicators, e.g., remote sensing, field measurement, and models; (2) generation factors, e.g., impervious urban surfaces, urban geometry, waste heat, vegetation, and pollutants; (3) environmental effects, e.g., urban climate, heat wave, ecology, and pollution; and (4) mitigation and adaption strategies, e.g., roof technology cooling, reflective cooling, vegetation cooling, and urban geometry cooling. A comparative analysis of popular issues revealed that UHI determination (intensity, heat source, supporting techniques) remains the central topic, whereas UHI impacts and mitigation strategies are becoming the popular issues that will receive increasing scientific attention in the future. Modeling will continue to be the

  4. Warm and Humid Air Blowing over Cold Water - Grand Banks Fog

    Science.gov (United States)

    Taylor, P.; Weng, W.

    2016-12-01

    The condensation of water vapour into droplets and the formation of fog in the Earth's atmospheric boundary layer involves a complex balance between horizontal advection and vertical turbulent mixing of heat and water vapour, cloud microphysical processes and radiative transfers of heat, plus the impact of water droplets, and sometimes ice crystals, on visibility. It is a phenomenon which has been studied for many years in a variety of contexts. On land, surface cooling of the ground via long wave radiation at night is often the trigger and a number of 1-D (height and time dependent) radiative fog models have been developed. Over the waters offshore from Newfoundland a key factor is the advection of moist air from over warm gulf stream waters to colder Labrador current water - an internal boundary-layer problem. Some basic properties can be learned from a steady state 2-D (x-z) model.The WTS (Weng, Taylor and Salmon, 2010, J. Wind Eng. Ind. Aerodyn. 98, 121-132 ) model of flow above changes in surface conditions has been used to investigate planetary boundary-layer flow over water with spatial changes in temperature, and to investigate situations leading to saturation and fog formation. Our turbulence closure includes the turbulent kinetic energy equation but we prefer to specify a height, surface roughness, Rossby number and local stability dependent, "master" length scale instead of a somewhat empirical dissipation or similar equation. Results show that fog can develop and extent to heights of order 100m in some conditions, depending on upstream profiles of wind, temperature and mixing ratio, and on solar radiation and the horizontal variations in water surface temperature.Next steps will involve validation against data being collected (by AMEC-Foster Wheeler in the Hibernia Management and Development Company Metocean project) over the Grand Banks and an interface with WRF and high resolution sea surface temperature data for forecasting fog conditions over the

  5. A Practical Approach to Water Education in Secondary Schools in Penang, Malaysia

    Science.gov (United States)

    Soo, P. W.; Cheam, C. S.

    2012-04-01

    In recent years, water problems have become a vital issue in our country, due to increasing population growth and urbanization. According to Prof Ngai Weng Chan, the President of Water Watch Penang (WWP), Malaysia has experienced mounting environmental degradation, and urban environmental woes in main cities like Penang. One of the many water issues affecting Malaysians is the sustainability of water that is closely related to unsustainable water supply management (Chan, 2004). Traditionally in Malaysia, Water Supply Management (WSM) and Water Demand Management (WDM) are based on the top-down-approach hierarchy. However, consumers have not been factored into the decision-making. As a result of increasing water consumption, many states in Malaysia are facing water shortages. We believe that the water consumers like our students can assist in water conservation. Education begins in school. We are certain that students with positive awareness can ultimately result in a water saving society in Malaysia. We have planned for a project that will be carried out at a local secondary school in Penang (Penang Chung Ling High School). The objective of this project is to increase the awareness among secondary students on water issues locally and globally. An initial 100 students from Chung Ling High School will be targeted for our project. We proposed to carry out water auditing of Penang Chung Ling High School to bring about awareness of water usage in the school premises for a period of time. Next, we will identify practical steps to help conserve water in Chung Ling High School. Part of the project includes formulating a water quiz to instill water awareness among the students. Hopefully with the effort to quantify the amount of water loss in unattended leaky taps will help adopting positive behavioral traits to enhance water conservation. Finally, we will look into ways to harvest rainfall for the school with the participation of these students.

  6. Can the default-mode network be described with one spatial-covariance network?

    Science.gov (United States)

    Habeck, Christian; Steffener, Jason; Rakitin, Brian; Stern, Yaakov

    2012-01-01

    The default-mode network (DMN) has become a well accepted concept in cognitive and clinical neuroscience over the last decade, and perusal of the recent literature attests to a stimulating research field of cognitive and diagnostic applications (for example, (Andrews-Hanna, Reidler, Huang, & Buckner, 2010; Koch et al., 2010; Sheline, Barch et al., 2009; Sheline, Raichle et al., 2009; Uddin et al., 2008; Uddin, Kelly, Biswal, Castellanos, & Milham, 2009; Weng et al., 2009; Yan et al., 2009)). However, a formal definition of what exactly constitutes a functional brain network is difficult to come by. In recent contributions, some researchers argue that the DMN is best understood as multiple interacting subsystems (Buckner, Andrews-Hanna, & Schacter, 2008) and have explored modular components of the DMN that have different functional specialization and could to some extent be identified separately (Fox et al., 2005; Harrison et al., 2008; Uddin et al., 2009). Such conception of modularity seems to imply an opposite construct of a ‘unified whole’, but it is difficult to locate proponents of the idea of a DMN who are supplying constraints that can be brought to bear on data in rigorous tests. Our aim in this paper is to present a principled way of deriving a single covariance pattern as the neural substrate of the DMN, test to what extent its behavior tracks the coupling strength between critical seed regions, and investigate to what extent our stricter concept of a network is consistent with the already established findings about the DMN in the literature. We show that our approach leads to a functional covariance pattern whose pattern scores are a good proxy for the integrity of the connections between a medioprefrontal, posterior cingulate and parietal seed regions. Our derived DMN network thus has potential for diagnostic applications that are simpler to perform than computation of pairwise correlational strengths or seed maps. PMID:22668988

  7. EnKF OSSE Experiments Assessing the Impact of HIRAD Wind Speed and HIWRAP Radial Velocity Data on Analysis of Hurricane Karl (2010)

    Science.gov (United States)

    Albers, Cerese; Sippel, Jason A.; Braun, Scott A.; Miller, Timothy

    2012-01-01

    Previous studies (e.g., Zhang et al. 2009, Weng et al. 2011) have shown that radial velocity data from airborne and ground-based radars can be assimilated into ensemble Kalman filter (EnKF) systems to produce accurate analyses of tropical cyclone vortices, which can reduce forecast intensity error. Recently, wind speed data from SFMR technology has also been assimilated into the same types of systems and has been shown to improve the forecast intensity of mature tropical cyclones. Two instruments that measure these properties were present during the NASA Genesis and Rapid Intensification Processes (GRIP) field experiment in 2010 which sampled Hurricane Karl, and will next be co-located on the same aircraft for the subsequent NASA HS3 experiment. The High Altitude Wind and Rain Profiling Radar (HIWRAP) is a conically scanning Doppler radar mounted upon NASAs Global Hawk unmanned aerial vehicle, and the usefulness of its radial velocity data for assimilation has not been previously examined. Since the radar scans from above with a fairly large fixed elevation angle, it observes a large component of the vertical wind, which could degrade EnKF analyses compared to analyses with data taken from lesser elevation angles. The NASA Hurricane Imaging Radiometer (HIRAD) is a passive microwave radiometer similar to SFMR, and measures emissivity and retrieves hurricane surface wind speeds and rain rates over a much wider swath. Thus, this study examines the impact of assimilating simulated HIWRAP radial velocity data into an EnKF system, simulated HIRAD wind speed, and HIWRAP+HIRAD with the Weather Research and Forecasting (WRF) model and compares the results to no data assimilation and also to the Truth from which the data was simulated for both instruments.

  8. Recombinant Gallid herpesvirus 2 with interrupted meq genes confers safe and efficacious protection against virulent field strains.

    Science.gov (United States)

    Zhang, Yanping; Liu, Changjun; Yan, Fuhai; Liu, Ailing; Cheng, Yun; Li, Zhijie; Sun, Guorong; Lv, Hongchao; Wang, Xiaomei

    2017-08-24

    Gallid herpesvirus 2 (GaHV-2) continuously evolves, which reduces the effectiveness of existing vaccines. To construct new GaHV-2 candidate vaccines, LMS, which is a virulent GaHV-2 field strain isolated from diseased chicken flocks in Southwest China in 2007, was modified such that both copies of its meq oncogene were partially deleted. The resulting virus, i.e., rMSΔmeq, was characterized using PCR and sequencing. To evaluate the safety and protective efficacy of rMSΔmeq, specific pathogen-free (SPF) chickens were inoculated with 2000 plaque forming units (pfu) and 20,000pfu of rMSΔmeq immediately after hatching. All birds grew well during the experimental period, and none of the challenged chickens developed Marek's disease-associated lymphoma. In addition, the rMSΔmeq- and CVI988/Rispens-vaccinated SPF chickens were challenged with 1000 pfu and 5000 pfu of the representative virulent GaHV-2 Md5 strain and 1000 pfu of the variant GaHV-2 strains LCC or LTS. The results showed that the rMSΔmeq strain provided complete protection, which was similar to that provided by the CVI988/Rispens vaccine (protective index (PI) of 95.5) when challenged with a conventional dose of the Md5 strain. However, rMSΔmeq provided a PI of 90.9 when challenged with 5000 pfu of the Md5 strain, which was significantly higher than that provided by the CVI988/Rispens vaccine (54.5). rMSΔmeq provided a PI of 86.4 against LCC, which was equal to that provided by the CVI988/Rispens vaccine (81.8). In addition, rMSΔmeq provided a PI of 100 against LTS, which was significantly higher than that provided by the CVI988/Rispens vaccine (68.2). Altogether, the rMSΔmeq virus provided efficient protection against representative and variant GaHV-2 strains. In conclusion, the rMSΔmeq virus is a safe and effective vaccine candidate for the prevention of Marek's disease and is effective against the Chinese variant GaHV-2 strains. Copyright © 2017. Published by Elsevier Ltd.

  9. CBIOS Science Sessions - 2015 - Part I

    Directory of Open Access Journals (Sweden)

    João Costa et al.

    2015-05-01

    Full Text Available Redox modulation by SOD mimics in renal cancer: from etiology to progression; Modulação redox por miméticos da SOD no cancro renal: da etiologia à progressão; João Costa. Role of the Notch pathway in female reproductive function; Papel da via Notch na função reprodutiva feminina; Daniel Murta; Marta Batista; Alexandre Trindade; Elisabete Silva; Luisa Mateus; António Duarte; Luís Costa. Skin permeation and in vivo antioxidant activity of gelatin nanoparticles; Permeação cutânea e actividade antioxidante in vivo de nanopartículas de gelatina; Camila Areias de Oliveira Isolation, modeling and phytosome forms of antiproliferative compounds from Plectranthus spp; Isolamento, modelação e formulações fitossomais de compostos antiproliferativos obtidos de plantas do género Plectranthus; Diogo Matias, Marisa Nicolai, A. S. Fernandes, Nuno Saraiva, M. Fátima Simões, Ana Diaz Lanza, Catarina Pinto Reis, Patricia Rijo. Role of SOD mimetics in breast cancer metastization; Papel de miméticos da SOD em metastização do cancro da mama; Ana Catarina Flórido. Royleanone derivatives from Plectranthus grandidentatus and its topical application through drug delivery nanosystems; Derivados de roileanona de Plectranthus grandidentatus e a sua aplicação tópica em nanossistemas para veiculação de fármacos; Filipe Pereira, M. J. Cebola, Rita Sobral, Ana Diaz Lanza, Lia Ascenção, Carlos Afonso, Catarina Pinto Reis, Patrícia Rijo. Research in dental veterinary medicine; Investigação em medicina dentária veterinária; João Filipe Requicha. Marek's disease virus (MDV ibiquitin-specific protease (USP performs critical functions beyond its enzymatic activity during virus replication; O papel das proteases específicas da ubiquitina na replicação viral e oncoginese induzida pelo virus da doença de Marek; Inês M.V. Veiga, Keith W. Jarosinski, Benedikt B. Kaufer, Nikolaus Osterrieder.

  10. Foreword

    International Nuclear Information System (INIS)

    Sujkowski, Z.

    1998-01-01

    The year 1997 was marked by the hundredth birthday anniversary of professor Andrzej Soltan, the first director of our Institute and the pioneer of nuclear physics in Poland. It is also about hundred years since nuclear physics has begun with the discovery of Polonium and Radium by Maria Sklodowska-Curie and Pierre Curie. In honour of these anniversaries an Exhibition entitled ''Nuclear Physics and Nuclear Technique in Service of Medicine - from Radium Needle to Accelerators'' has been organized. Some lectures, radio broadcasts, popular level articles have supplemented this effort to bring the present day nuclear sciences closer to the general public. In the year of 1997 227 articles in international journals have been published, supplemented by 24 invited talks and 219 communications at conferences. The lists of these publications are given separately for each of the Research Departments throughout this Annual Report. They are preceded by articles on the work in progress and by the brief overviews written by the Department Heads. The selected highlights of the past year are: progress in materials science (deep surface layers - on transformation of uranium lattice induced by water corrosion). The work on modification of surface properties by hot and cold ion implantation. In nuclear physics the careful study of polarization phenomena in the decay of light, weekly bound nuclei. The works on the properties of the heaviest elements have been continued (Adam Sobiczewski - international prizes: in 1997 the Alfred Jurzykowski and the Flerov prize). The study of new scintillation techniques provided by Marek Moszynski has also mentioned. The highlight this time is the demonstration of advantages offered by avalanche diodes for the light output readout. The particle physicists continue their involvement in various international projects. This year they managed to give a noteworthy instrumental and technical input to: Resistive Plate Chambers for the Compact Muon Solenoid

  11. Emerging treatments in type 2 diabetes: focus on canagliflozin

    Directory of Open Access Journals (Sweden)

    Rosiak M

    2014-08-01

    Full Text Available Marek Rosiak,1,2 Susanna Grzeszczak,2 Dariusz A Kosior,2,3 Marek Postuła1,2 1Department of Cardiology and Hypertension, Central Clinical Hospital, the Ministry of the Interior, Warsaw, Poland; 2Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland; 3Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland Abstract: Type 2 diabetes mellitus (T2DM is a prevalent metabolic disorder, which affects more than 300 million people globally. The common effect of uncontrolled diabetes is the state of hyperglycemia, which results from beta-cell dysfunction as well as insulin resistance, which is accompanied with microvascular and macrovascular complications. As hyperglycemia defines diabetes, glycemic control is fundamental to the management of diabetes. Sodium glucose co-transporter 2 inhibitors (SGLT2 are a new group of oral antidiabetic medications that act by blocking the reabsorption of glucose, causing it to be excreted in the urine. Canagliflozin was the first SGLT2 inhibitor to be approved in the US by the Food and Drug Administration for the treatment and control of T2DM and on September 19, 2013, the Committee for Medicinal Products for Human Use of the European Medicines Agency adopted a positive opinion, recommending the granting of a marketing authorization for the medicinal product Invokana®. Canagliflozin is a SGLT2 inhibitor, which acts upon the proximal tubules of the kidneys and reduces the renal threshold for glucose. It is highly selective, binding 250 times more potently to SGLT2 than sodium glucose co-transporter 1 inhibitor. This action allows a higher amount of glucose to be excreted within the urine, causing the patient's plasma glucose level to be decreased and indirectly causing weight loss. Among the most common adverse events are hypoglycemia, headache, nausea, female genital and urinary tract infections, nasopharyngitis, and transient postural dizziness. Given its

  12. Long range personalized cancer treatment strategies incorporating evolutionary dynamics.

    Science.gov (United States)

    Yeang, Chen-Hsiang; Beckman, Robert A

    2016-10-22

    approaches, by far the majority show an advantage of multi-step or ALTO over single-step optimization. ALTO-SMO delivers cure rates superior or equal to those of single- or multi-step optimization, in 2 and 3 drug cases respectively. In selected virtual patients incurable by dynamic precision medicine using single-step optimization, analogous strategies that "think ahead" can deliver long-term survival and cure without any disadvantage for non-responders. When therapies require dose reduction in combination (due to toxicity), optimal strategies feature complex patterns involving rapidly interleaved pulses of combinations and high dose monotherapy. This article was reviewed by Wendy Cornell, Marek Kimmel, and Andrzej Swierniak. Wendy Cornell and Andrzej Swierniak are external reviewers (not members of the Biology Direct editorial board). Andrzej Swierniak was nominated by Marek Kimmel.

  13. Foreword

    Energy Technology Data Exchange (ETDEWEB)

    Sujkowski, Z. [The Andrzej Soltan Institute for Nuclear Studies, Otwock-Swierk (Poland)

    1998-12-31

    The year 1997 was marked by the hundredth birthday anniversary of professor Andrzej Soltan, the first director of our Institute and the pioneer of nuclear physics in Poland. It is also about hundred years since nuclear physics has begun with the discovery of Polonium and Radium by Maria Sklodowska-Curie and Pierre Curie. In honour of these anniversaries an Exhibition entitled ``Nuclear Physics and Nuclear Technique in Service of Medicine - from Radium Needle to Accelerators`` has been organized. Some lectures, radio broadcasts, popular level articles have supplemented this effort to bring the present day nuclear sciences closer to the general public. In the year of 1997 227 articles in international journals have been published, supplemented by 24 invited talks and 219 communications at conferences. The lists of these publications are given separately for each of the Research Departments throughout this Annual Report. They are preceded by articles on the work in progress and by the brief overviews written by the Department Heads. The selected highlights of the past year are: progress in materials science (deep surface layers - on transformation of uranium lattice induced by water corrosion). The work on modification of surface properties by hot and cold ion implantation. In nuclear physics the careful study of polarization phenomena in the decay of light, weekly bound nuclei. The works on the properties of the heaviest elements have been continued (Adam Sobiczewski - international prizes: in 1997 the Alfred Jurzykowski and the Flerov prize). The study of new scintillation techniques provided by Marek Moszynski has also mentioned. The highlight this time is the demonstration of advantages offered by avalanche diodes for the light output readout. The particle physicists continue their involvement in various international projects. This year they managed to give a noteworthy instrumental and technical input to: Resistive Plate Chambers for the Compact Muon Solenoid

  14. The influence of atypical antipsychotic drugs on sexual function

    Directory of Open Access Journals (Sweden)

    Just MJ

    2015-07-01

    Full Text Available Marek J Just Department of General and Endocrine Surgery, Piekary Medical Centre, Piekary Slaskie, Poland Abstract: Human sexuality is contingent upon many biological and psychological factors. Such factors include sexual drive (libido, physiological arousal (lubrication/erection, orgasm, and ejaculation, as well as maintaining normal menstrual cycle. The assessment of sexual dysfunction can be difficult due to the intimate nature of the problem and patients’ unwillingness to discuss it. Also, the problem of dysfunction is often overlooked by doctors. Atypical antipsychotic treatment is a key component of mental disorders’ treatment algorithms recommended by the National Institute of Health and Clinical Excellence, the American Psychiatric Association, and the British Society for Psychopharmacology. The relationship between atypical antipsychotic drugs and sexual dysfunction is mediated in part by antipsychotic blockade of pituitary dopamine D2 receptors increasing prolactin secretion, although direct correlations have not been established between raised prolactin levels and clinical symptoms. Variety of mechanisms are likely to contribute to antipsychotic-related sexual dysfunction, including hyperprolactinemia, sedation, and antagonism of a number of neurotransmitter receptors (α-adrenergic, dopaminergic, histaminic, and muscarinic. Maintaining normal sexual function in people treated for mental disorders can affect their quality of life, mood, self-esteem, attitude toward taking medication, and compliance during therapy. Keywords: schizophrenia, galactorrhea, hyperprolactinemia, mood disorders, anorgasmia

  15. Isolation and serological differentiation of a herpesvirus from bobwhite quail (Colinus virginianus, L. 1758).

    Science.gov (United States)

    Kaleta, E F; Marschall, H J; Glünder, G; Stiburek, B

    1980-01-01

    An infectious agent was isolated from the liver of bobwhite quails (Colinus virginianus, L. 1758). The agent was sensitive to chloroform and its multiplication was inhibited by 5-iodine-2-deoxy-uridine. It passed filters with a pore diameter of 220 nm and more but not 100 nm filters. Electron microscopic examination revealed numerous nucleocapsids with hollow capsomeres and few enveloped particles in the supernatant fluids of infected cultures. The nucleocapsids were calculated to have 162 capsomeres on their surface. Using the plaque reduction method for neutralization tests no serological cross reactions could be detected between the quail isolate and sera against Marek's disease virus, turkey herpes-virus (HV), duck enteritis HV, infectious laryngotracheitis HV, amazon parrot HV, great horned owl HV, eagle owl HV, snowy owl HV, falcon HV, pigeon HV, Lake Victoria Cormorant HV, and stork HV. The isolate from bobwhite quail did only cross-react with antiserum against crane HV. It is concluded that the isolated virus is a member of the avian herpesvirus group and it is proposed to tentatively term it herpesvirus colinum (from Colinus virginianus = bobwhite quail).

  16. Developing computer-based training programs for basic mammalian histology: Didactic versus discovery-based design

    Science.gov (United States)

    Fabian, Henry Joel

    Educators have long tried to understand what stimulates students to learn. The Swiss psychologist and zoologist, Jean Claude Piaget, suggested that students are stimulated to learn when they attempt to resolve confusion. He reasoned that students try to explain the world with the knowledge they have acquired in life. When they find their own explanations to be inadequate to explain phenomena, students find themselves in a temporary state of confusion. This prompts students to seek more plausible explanations. At this point, students are primed for learning (Piaget 1964). The Piagetian approach described above is called learning by discovery. To promote discovery learning, a teacher must first allow the student to recognize his misconception and then provide a plausible explanation to replace that misconception (Chinn and Brewer 1993). One application of this method is found in the various learning cycles, which have been demonstrated to be effective means for teaching science (Renner and Lawson 1973, Lawson 1986, Marek and Methven 1991, and Glasson & Lalik 1993). In contrast to the learning cycle, tutorial computer programs are generally not designed to correct student misconceptions, but rather follow a passive, didactic method of teaching. In the didactic or expositional method, the student is told about a phenomenon, but is neither encouraged to explore it, nor explain it in his own terms (Schneider and Renner 1980).

  17. „Ósmy dzień tygodnia”

    Directory of Open Access Journals (Sweden)

    Anna Zawadzka

    2012-12-01

    Full Text Available “The Eighth Day of the Week” The Eighth Day of the Week is a short story by Marek Hłasko revolving around the topic of losing virginity. Literary scholars consider Hłasko as a representative of machismo; a masculine and male-centred narrator. This text analyses and deconstructs the short story defending it as a comprehensive record of misogynist culture written from the perspective of the main female protagonist and not the expression of misogyny of the author himself. The tools of discourse analysis and feminist philosophy applied to Hłasko’s text produce surprising results. Agnieszka – the main female protagonist of the short story – turns out to be a figure of non-conformity universalised by Hłasko, while the virginity and its loss become a part of female fate used by Hłasko as a motif to show the power of society over an individual. Meanwhile Agnieszka struggles for autonomy from domineering cultural patterns and gains it with the help of not so much barricades and spectacular gestures typical for male protagonists as wit, intelligence and trickery.

  18. A Concise Dictionary of Transparency

    Directory of Open Access Journals (Sweden)

    Jakub Misun

    2013-01-01

    Full Text Available The article discusses an essay collection by Marek Bieńczyk, Przeźroczystość [Transparency]. The concept, placed in various context, shows various aspects and is seen in various shades. The author does not put forward a statement, but rather proposes a work to be done: to determine the modality of transparency. The concept initially seems to be mainly epistemological: the cognizant subject would like to make the world transparent, to discover all possible mysteries. Before that, however, the subject must know itself, and here the dream of trans­parency also plays the key role. Lack of epistemological transparency is the main cause of melancholy and its reverse — hysteria. The concept turns out to be important in the domain of love — the loer thinks that (she knows the desired person more better anybody else, that (she has entirely penetrated the subjectivity of the Other. Ultimately, however, the dream of transparency goes down to a slow demise of the subject: as self-discovery progresses, there is less and less of the discoverer. In conclusion of this work, the border of modality of the concept turns out to be horrifyingly obvious. The desire for transparency consequently searches not for knowledge, but for an escape whose name is death.

  19. The potential of medical device industry in technological and economical context

    Directory of Open Access Journals (Sweden)

    Maresova P

    2015-10-01

    Full Text Available Petra Maresova,1 Marek Penhaker,1,2 Ali Selamat,1,3 Kamil Kuca1,41Faculty of Informatics and Management, University of Hradec Králové, Hradec Králové, Czech Republic; 2Department of Cybernetics and Biomedical Engineering, Faculty of Electrical Engineering and Computer Science, Technical University of Ostrava, Poruba, Czech Republic; 3Faculty of Computing, Universiti Teknologi Malaysia, Johor Bahru, Johor, Malaysia; 4Center for Biomedical Research, University Hospital Hradec Králové, Hradec Králové, Czech RepublicAbstract: The high quality of public health improves not only healthy life expectancy, but also the productivity of labor. The most important part of the health care sector is the medical technology industry. The aim of this study is to analyze the current situation in the medical device industry in Europe, its potential strengths and weaknesses in the context of topical economic and demographic development. The contribution specifies an analysis of the economic state of the medical device industry in the context of demographic development of European Union’s macroeconomic indicators and views of experts in the field of medical device development, concerning the opportunities for entities involved in the medical device market. There is fierce competition on the European market. The innovative activity is stable and well regulated by responsible authorities. Worldwide, the medical device market is expected to grow.Keywords: technology context, medical device, Europe, expenditure, review

  20. [HUGO STEINHAUS--CO-FOUNDER OF THE LWÓW SCHOOL OF MATHEMATICS].

    Science.gov (United States)

    Wócik, Wiesław

    2014-01-01

    The paper is dedicated to the presentation of professor Hugo Steinhaus--co-founder of the Lwów School of Mathematics. It is indicated that had it not been for the scholar, the founding and development of the Lwów School of Mathematics would have been almost impossible. The analyses focus on his undertakings during the Lvov period in the early 1920s and those events that preceded the founding of the school (namely Steinhaus's education at the Göttingen University, various meetings and gatherings, discussions, first fascinations and mathematical dissertations). This paper, however, does not look into the scientific output of Steinhaus, only presents his method of scientific work and highlights the strategy that he chose in order to create the scientific community. An attempt has been also made to justify the effectiveness of the adopted strategy by describing the scientific atmosphere of Lvov and intellectual potential of the students of the school. Steinhaus's activities in the 1930s will be only marginally presented with an impact on particularly interesting cooperation with the alumni of the Lwów School of Mathematics--Marek Kac, Stefan Kaczmarz, Paweł Nikliborec and scholars from other fields of science (as part of the process of the application of mathematics).

  1. LHC gets the ball rolling

    CERN Multimedia

    2007-01-01

    A technique involving a small ball with a transmitter embedded inside it has been successfully tested in Sector 7-8. The ball is sent through the LHC beam pipes to check the LHC interconnections. The multidisciplinary team responsible for the RF ball project to check the interconnections. From left to right: Rhodri Jones (AB/BI), Eva Calvo (AB/BI), Francesco Bertinelli (AT/MCS), Sonia Bartolome Jimenez (TS/IC), Sylvain Weisz (TS/IC), Paul Cruikshank (AT/VAC), Willemjan Maan (AT/VAC), Alain Poncet (AT/MCS), Marek Gasior (AB/BI). During the tests the ball is inserted very carefully into the vacuum chamber.A game of ping-pong at the LHC? On 13 September a rather unusual test was carried out in Sector 7-8 of the accelerator. A ball just a bit smaller than a ping-pong ball was carefully introduced into one of the accelerator’s two vacuum pipes, where it travelled 800 metres in the space of a few mi...

  2. Health evaluation of Galapagos Hawks (Buteo galapagoensis) on Santiago Island, Galapagos.

    Science.gov (United States)

    Deem, Sharon L; Rivera-Parra, Jose Luis; Parker, Patricia G

    2012-01-01

    Galapagos Hawks (Buteo galapagoensis), the only endemic, diurnal raptor species in Galapagos, are currently distributed on eight Galapagos Islands having been extirpated from three of the human-inhabited islands. In January 2009, we performed health assessments of 89 Galapagos Hawks on Santiago Island, Galapagos. Four of the 89 Galapagos Hawks (4%) evaluated had physical abnormalities. Blood parameters did not differ between males and females, except for aspartate transaminase values, which were significantly higher in females than males. No Galapagos Hawks tested positive for antibodies to avian encephalitis virus, Marek virus, and paramyxovirus-1 or to haemosporidian antigen. Chlamydophila psittaci antigen was detected in 2 of 86 Galapagos Hawks (2%), with 24 of 43 Galapagos Hawks (56%) antibody-positive for avian adenovirus-1 and 1 of 48 Galapagos Hawks (2%) antibody positive for Toxoplasma gondii. There were no significant differences in infectious disease results based on sex. This study contributes to the understanding of the health status of the Galapagos Hawk and to the establishment of baseline information for the species.

  3. Vacuum chambers full of ideas for the Swedish synchrotron

    CERN Multimedia

    Corinne Pralavorio

    2016-01-01

    CERN’s Vacuum, Surfaces and Coatings group has contributed to the development of vacuum chambers for the MAX IV synchrotron, which has just been officially opened in Sweden.   A section of the new 3 GeV MAX IV synchrotron at the time of installation. In the centre of the magnets you can see the vacuum chamber developed in collaboration with CERN. (Photo: Marek Grabski, MAX IV Vacuum group) On 21 June, the King and the Prime Minister of Sweden officially opened MAX IV, a brand-new synchrotron in Lund, Sweden. The summer solstice, the longest day of the year, was deliberately chosen for the ceremony: MAX IV, a cutting-edge synchrotron, will deliver the brightest X-rays ever produced to more than 2000 users. Some 1500 kilometres away, a team at CERN followed the opening ceremony with a touch of pride. The Vacuum, Surfaces and Coatings group in the Technology department (TE-VSC) participated in the construction of this new synchrotron. Its contribution lies at the very hea...

  4. Acute paretic syndrome in juvenile White Leghorn chickens resembles late stages of acute inflammatory demyelinating polyneuropathies in humans

    Directory of Open Access Journals (Sweden)

    Preisinger Rudolf

    2010-01-01

    Full Text Available Abstract Background Sudden limb paresis is a common problem in White Leghorn flocks, affecting about 1% of the chicken population before achievement of sexual maturity. Previously, a similar clinical syndrome has been reported as being caused by inflammatory demyelination of peripheral nerve fibres. Here, we investigated in detail the immunopathology of this paretic syndrome and its possible resemblance to human neuropathies. Methods Neurologically affected chickens and control animals from one single flock underwent clinical and neuropathological examination. Peripheral nervous system (PNS alterations were characterised using standard morphological techniques, including nerve fibre teasing and transmission electron microscopy. Infiltrating cells were phenotyped immunohistologically and quantified by flow cytometry. The cytokine expression pattern was assessed by quantitative real-time PCR (qRT-PCR. These investigations were accomplished by MHC genotyping and a PCR screen for Marek's disease virus (MDV. Results Spontaneous paresis of White Leghorns is caused by cell-mediated, inflammatory demyelination affecting multiple cranial and spinal nerves and nerve roots with a proximodistal tapering. Clinical manifestation coincides with the employment of humoral immune mechanisms, enrolling plasma cell recruitment, deposition of myelin-bound IgG and antibody-dependent macrophageal myelin-stripping. Disease development was significantly linked to a 539 bp microsatellite in MHC locus LEI0258. An aetiological role for MDV was excluded. Conclusions The paretic phase of avian inflammatory demyelinating polyradiculoneuritis immunobiologically resembles the late-acute disease stages of human acute inflammatory demyelinating polyneuropathy, and is characterised by a Th1-to-Th2 shift.

  5. Evolution of viral virulence: empirical studies

    Science.gov (United States)

    Kurath, Gael; Wargo, Andrew R.

    2016-01-01

    The concept of virulence as a pathogen trait that can evolve in response to selection has led to a large body of virulence evolution theory developed in the 1980-1990s. Various aspects of this theory predict increased or decreased virulence in response to a complex array of selection pressures including mode of transmission, changes in host, mixed infection, vector-borne transmission, environmental changes, host vaccination, host resistance, and co-evolution of virus and host. A fundamental concept is prediction of trade-offs between the costs and benefits associated with higher virulence, leading to selection of optimal virulence levels. Through a combination of observational and experimental studies, including experimental evolution of viruses during serial passage, many of these predictions have now been explored in systems ranging from bacteriophage to viruses of plants, invertebrates, and vertebrate hosts. This chapter summarizes empirical studies of viral virulence evolution in numerous diverse systems, including the classic models myxomavirus in rabbits, Marek's disease virus in chickens, and HIV in humans. Collectively these studies support some aspects of virulence evolution theory, suggest modifications for other aspects, and show that predictions may apply in some virus:host interactions but not in others. Finally, we consider how virulence evolution theory applies to disease management in the field.

  6. An overview on avian influenza

    Directory of Open Access Journals (Sweden)

    Nelson Rodrigo da Silva Martins

    2012-06-01

    Full Text Available Avian influenza (AI is considered an exotic disease in the Brazilian poultry industry, according to the National Avian Health Program (PNSA, with permanent monitoring of domestic, exotic and native avian species. Brazil presents privileged environmental conditions of reduced risk. In addition, all commercial poultry and conservation holdings are registered in state or national inventories and geographically located (GPS for health control. Poultry health standards are adopted for the conformity to the international market, mostly for the intensified poultry destined for exportation, but also for companion exotic and native conservation facilities. Guidelines for monitoring and the diagnosis of AI are published by the PNSA and follow the standards proposed by the international health code (World Organization for Animal Health, Organization International des Epizooties - OIE and insure the free of status for avian influenza virus (AIV of LPAIV-low pathogenicity AIV and HPAIV-high pathogenicity AIV. In addition, the infections by mesogenic and velogenic Newcastle disease virus, Mycoplasma gallisepticum, M. synoviae and M. meleagridis, Salmonella enteric subspecies enterica serovar Gallinarum biovars Gallinarum and Pullorum are eradicated from reproduction. Controlled infections by S.enterica subspecies enterica serovars Enteritidis and Typhimurium are monitored for breeders. The vaccination of chickens in ovo or at hatch against Marek's disease is mandatory. Broiler production is an indoor activity, confinement which insures biosecurity, with safe distances from the potential AIV reservoir avian species. Worldwide HPAIV H5N1 notifications to the OIE, in March 2011, included 51 countries.

  7. Animal genomics and infectious disease resistance in poultry.

    Science.gov (United States)

    Smith, J; Gheyas, A; Burt, D W

    2016-04-01

    Avian pathogens are responsible for major costs to society, both in terms of huge economic losses to the poultry industry and their implications for human health. The health and welfare of millions of birds is under continued threat from many infectious diseases, some of which are increasing in virulence and thus becoming harder to control, such as Marek's disease virus and avian influenza viruses. The current era in animal genomics has seen huge developments in both technologies and resources, which means that researchers have never been in a better position to investigate the genetics of disease resistance and determine the underlying genes/mutations which make birds susceptible or resistant to infection. Avian genomics has reached a point where the biological mechanisms of infectious diseases can be investigated and understood in poultry and other avian species. Knowledge of genes conferring disease resistance can be used in selective breeding programmes or to develop vaccines which help to control the effects of these pathogens, which have such a major impact on birds and humans alike.

  8. Essay and Ekphrasis (Herbert - Bieńkowska - Bieńczyk

    Directory of Open Access Journals (Sweden)

    Roma Sendyka

    2009-01-01

    Full Text Available Michel Riffaterre in article L'lllusion d'ekphrasis put forward an idea of "critical ekphrasis" (1994 what may become an invitation to ask if other sub-genres/modes of ekphrasis may be described. The text Essay and Ekphrasis develops this question in the field of essayistic traditions. Evoking the tendency of writing on art in that genre (from Montaigne, Diderot, Ruskin, Pater to art historians, critics and artists the article analyses three examples of ekphrases (by Zbigniew Herbert, Ewa Bieńkowska and Marek Bieńczyk to voice a hypothesis that ekphrasis in an essay may be a useful proof for those who question (ostensive representational powers of that textual tool. Essayistic ekphrasis seems to have a foremost referential character, pointing towards an object of art only to use it in order to describe cognitive procedures of the subject who in such a way (performatively and not overtly pictures himself mirroring his inner self in dispersed fragments of cultural object, dismantling the temporal and spatial difference between the viewer and the object in an illusion of an immediate presence.

  9. Two diagnoses become one? Rare case report of anorexia nervosa and Cushing’s syndrome

    Directory of Open Access Journals (Sweden)

    Sawicka N

    2013-03-01

    Full Text Available Nadia Sawicka,* Maria Gryczyńska,* Jerzy Sowiński, Monika Tamborska-Zedlewska, Marek Ruchała Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland*These authors contributed equally to this workAbstract: Hypothalamic-pituitary-adrenal axis impairment in anorexia nervosa is marked by hypercortisolemia, and psychiatric disorders occur in the majority of patients with Cushing’s syndrome. Here we report a patient diagnosed with anorexia nervosa who also developed Cushing’s syndrome. A 26-year-old female had been treated for anorexia nervosa since she was 17 years old, and also developed depression and paranoid schizophrenia. She was admitted to the Department of Endocrinology, Metabolism, and Internal Medicine with a preliminary diagnosis of Cushing’s syndrome. Computed tomography revealed a 27 mm left adrenal tumor, and she underwent laparoscopic adrenalectomy. She was admitted to hospital 6 months after this procedure, at which time she did not report any eating or mood disorder. This is a rare case report of a patient with anorexia nervosa in whom Cushing’s syndrome was subsequently diagnosed. Diagnostic difficulties were caused by the signs and symptoms presenting in the course of both disorders, ie, hypercortisolemia, osteoporosis, secondary amenorrhea, striae, hypokalemia, muscle weakness, and depression.Keywords: anorexia nervosa, Cushing’s syndrome, adrenalectomy, osteoporosis

  10. Melting hadrons, boiling quarks from Hagedorn temperature to ultra-relativistic heavy-ion collisions at CERN : with a tribute to Rolf Hagedorn

    CERN Document Server

    2015-01-01

    This book shows how the study of multi-hadron production phenomena in the years after the founding of CERN culminated in Hagedorn's pioneering idea of limiting temperature, leading on to the discovery of the quark-gluon plasma - announced, in February 2000 at CERN. Following the foreword by Herwig Schopper -- the Director General (1981-1988) of CERN at the key historical juncture -- the first part is a tribute to Rolf Hagedorn (1919-2003) and includes contributions by contemporary friends and colleagues, and those who were most touched by Hagedorn: Tamás Biró, Igor Dremin, Torleif Ericson, Marek Gázdzicki, Mark Gorenstein, Hans Gutbrod, Maurice Jacob, István Montvay, Berndt Müller, Grazyna Odyniec, Emanuele Quercigh, Krzysztof Redlich, Helmut Satz, Luigi Sertorio, Ludwik Turko, and Gabriele Veneziano. The second and third parts retrace 20 years of developments that after discovery of the Hagedorn temperature in 1964 led to its recognition as the melting point of hadrons into boiling quarks, and t...

  11. 103rd Meeting of the SPSC

    CERN Multimedia

    Morna Robillard

    2011-01-01

    from Tuesday 25 October 2011 at 09:00 to Wednesday 26 October 2011 at 16:00 Council Chamber, Bldg. 503 News from the Non-LHC Experiments at CERN Claude Vallee / CPPM Marseille Tuesday 25 October 2011 09:00 - 13:00 OPEN SESSION 09:00 Status and plans of the NA61 experiment 30' Speaker:  Marek Gazdzicki / Johann-Wolfgang-Goethe Univ. (DE) 09:40 Status and plans of the NA63 experiment 20' Speaker:  Ulrik Uggerhoj 10:10 Status and plans of the CAST experiment 30' Speaker:  Esther Ferrer Ribas / IRFU/CEA-Saclay 10:50 Coffee Break 20' 11:10 Status and plans of the OSQAR experiment 30' Speaker:  Pierre Pugnat / CNRS - LNCMI-G (Laboratoire National des Champs Magnétiques Intenses de Grenoble 11:50 Status and plans of the UA9 experiment 20' Speaker:  Walter Scandale / Universite de Paris-Sud 11 (FR) 12:20 A proposal to measure the gravitational behaviour of antihydrogen at rest 30' Speaker:  Patr...

  12. Enhancement of oral bioavailability of cyclosporine A: comparison of various nanoscale drug-delivery systems

    Directory of Open Access Journals (Sweden)

    Wang K

    2014-10-01

    Full Text Available Kai Wang,1–3 Jianping Qi,1 Tengfei Weng,1,2 Zhiqiang Tian,1 Yi Lu,1 Kaili Hu,4 Zongning Yin,2 Wei Wu1 1School of Pharmacy, Fudan University, Key Laboratory of Smart Drug Delivery of Ministry of Education, Shanghai, People’s Republic of China; 2West China School of Pharmacy, Sichuan University, Chengdu, Sichuan, People’s Republic of China; 3Tropical Crops Genetic Resources Institute, Hainan Provincial Engineering Research Center for Blumea Balsamifera, Chinese Academy of Tropical Agricultural Sciences, Danzhou, Hainan, People’s Republic of China; 4Murad Research Center for Modernized Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of ChinaAbstract: A variety of nanoscale delivery systems have been shown to enhance the oral absorption of poorly water-soluble and poorly permeable drugs. However, the performance of these systems has seldom been evaluated simultaneously. The aim of this study was to compare the bioavailability enhancement effect of lipid-based nanocarriers with poly(lactic-co-glycolic acid (PLGA nanoparticles (NPs to highlight the importance of the lipid composition, with cyclosporine A (CyA as a model drug. CyA-loaded PLGA NPs, nanostructured lipid carriers (NLCs, and self-microemulsifying drug-delivery systems (SMEDDS were prepared. The particle size of PLGA NPs (182.2±12.8 nm was larger than that of NLCs (89.7±9.0 nm and SMEDDS (26.9±1.9 nm. All vehicles are charged negatively. The entrapment efficiency of PLGA NPs and NLCs was 87.6%±1.6% and 80.3%±0.6%, respectively. In vitro release tests indicated that the cumulative release of CyA was lower than 4% from all vehicles, including Sandimmun Neoral®, according to the dialysis method. Both NLCs and SMEDDS showed high relative oral bioavailability, 111.8% and 73.6%, respectively, after oral gavage administration to beagle dogs, which was not statistically different from commercial Sandimmun Neoral®. However, PLGA NPs

  13. Association of American Geographers, Remote Sensing Specialty Group Special Issue of Geocarto International

    Science.gov (United States)

    Allen, Thomas R. (Editor); Emerson, Charles W. (Editor); Quattrochi, Dale A. (Editor); Arnold, James E. (Technical Monitor)

    2001-01-01

    This special issue continues the precedence of the Association of American Geographers (AAG), Remote Sensing Specialty Group (RSSG) for publishing selected articles in Geocarto International as a by-product from the AAG annual meeting. As editors, we issued earlier this year, a solicitation for papers to be published in a special issue of Geocarto International that were presented in RSSG-sponsored sessions at the 2001 AAG annual meeting held in New York City on February 27-March 3. Although not an absolute requisite for publication, the vast majority of the papers in this special issue were presented at this year's AAG meeting in New York. Other articles in this issue that were not part of a paper or poster session at the 2001 AAG meeting are authored by RSSG members. Under the auspices of the RSSG, this special Geocarto International issue provides even more compelling evidence of the inextricable linkage between remote sensing and geography. The papers in this special issue fall into four general themes: 1) Urban Analysis and Techniques for Urban Analysis; 2) Land Use/Land Cover Analysis; 3) Fire Modeling Assessment; and 4) Techniques. The first four papers herein are concerned with the use of remote sensing for analysis of urban areas, and with use or development of techniques to better characterize urban areas using remote sensing data. As the lead paper in this grouping, Rashed et al., examine the usage of spectral mixture analysis (SMA) for analyzing satellite imagery of urban areas as opposed to more 'standard' methods of classification. Here SMA has been applied to IRS-1C satellite multispectral imagery to extract measures that better describe the 'anatomy' of the greater Cairo, Egypt region. Following this paper, Weng and Lo describe how Landsat TM data have been used to monitor land cover types and to estimate biomass parameters within an urban environment. The research reported in this paper applies an integrated GIS (Geographic Information System

  14. A novel nanobody specific for respiratory surfactant protein A has potential for lung targeting

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    Wang SM

    2015-04-01

    Full Text Available Shan-Mei Wang,1,* Xian He,2,* Nan Li,1,* Feng Yu,3 Yang Hu,1 Liu-Sheng Wang,1 Peng Zhang,4 Yu-Kui Du,1 Shan-Shan Du,1 Zhao-Fang Yin,1 Ya-Ru Wei,1 Xavier Mulet,5 Greg Coia,6 Dong Weng,1 Jian-Hua He,3 Min Wu,7 Hui-Ping Li1 1Department of Respiratory Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 2School of Medicine, Suzhou University, SuZhou, 3Shanghai Institute of Applied Physics, Chinese Academy of Sciences, 4Department of Chest Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, People’s Republic of China; 5CSIRO (Commonwealth Scientific and Industrial Research Materials Science and Engineering, Clayton, 6CSIRO Materials Science and Engineering, Parkville, Melbourne, VIC, Australia; 7Department of Basic Sciences, University of North Dakota, Grand Forks, ND, USA *These authors contributed equally to this work Abstract: Lung-targeting drugs are thought to be potential therapies of refractory lung diseases by maximizing local drug concentrations in the lung to avoid systemic circulation. However, a major limitation in developing lung-targeted drugs is the acquirement of lung-specific ligands. Pulmonary surfactant protein A (SPA is predominantly synthesized by type II alveolar epithelial cells, and may serve as a potential lung-targeting ligand. Here, we generated recombinant rat pulmonary SPA (rSPA as an antigen and immunized an alpaca to produce two nanobodies (the smallest naturally occurring antibodies specific for rSPA, designated Nb6 and Nb17. To assess these nanobodies’ potential for lung targeting, we evaluated their specificity to lung tissue and toxicity in mice. Using immunohistochemistry, we demonstrated that these anti-rSPA nanobodies selectively bound to rat lungs with high affinity. Furthermore, we intravenously injected fluorescein isothiocyanate-Nb17 in nude mice and observed its preferential accumulation in the lung to other tissues, suggesting high

  15. Elementary Steps of Faujasite Formation Followed by in Situ Spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Prodinger, Sebastian [Institute; Vjunov, Aleksei [Institute; Hu, Jian Zhi [Institute; Fulton, John L. [Institute; Camaioni, Donald M. [Institute; Derewinski, Miroslaw A. [Institute; Lercher, Johannes A. [Institute; Department

    2018-01-24

    Ex situ and in situ spectroscopy was used to identify the kinetics of processes during the formation of the faujasite (FAU) zeolite lattice from a hydrous gel. Using solid-state 27Al MAS NMR, the autocatalytic transformation from the amorphous gel into the crystalline material was monitored. Al-XANES shows that most Al already adopts a tetrahedral coordination in the X-ray-amorphous aluminosilicate at the beginning of the induction period, which hardly changes throughout the rest of the synthesis. Using 23Na NMR spectroscopy, environments in the growing zeolite crystal were identified and used to define the processes in the stepwise formation of the zeolite lattice. The end of the induction period was accompanied by a narrowing of the 27Al and 23Na MAS NMR peak widths, indicating the increased long-range order. The experiments show conclusively that the formation of faujasite occurs via the continuous formation and subsequent condensation of intermediary sodalite-like units that constitute the key building block of the zeolite. Acknowledgement The authors thank T. Huthwelker for assistance with XAFS experiment setup at the Swiss Light Source (PSI, Switzerland). Further, we would like to acknowledge V. Shutthanandan and B.W. Arey for performing Helium ion microscopy as well as Z. Zhao, N.R. Jaeger, M. Weng, C. Wan and M. Hu for aiding in the NMR experimental procedure. T. Varga is acknowledged for his help with the capillary XRD. A.V., D.M.C., J.H., J.L.F and J.A.L. were supported by the US Department of Energy, Office of Science, Office of Basic Energy Sciences. S.P. and M.A.D. acknowledge support by the Materials Synthesis and Simulation Across Scales (MS3 Initiative) conducted under Laboratory Directed Research & Development Program at PNNL. The in situ NMR experiments were supported by the U. S. Department of Energy (DOE), Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Biosciences and Geosciences. Part of the research

  16. Biosynthesis of gold nanoparticles by the extreme bacterium Deinococcus radiodurans and an evaluation of their antibacterial properties

    Directory of Open Access Journals (Sweden)

    Li J

    2016-11-01

    Full Text Available Jiulong Li,1,* Qinghao Li,1,* Xiaoqiong Ma,2,* Bing Tian,1 Tao Li,1 Jiangliu Yu,1 Shang Dai,1 Yulan Weng,1 Yuejin Hua1 1Key Laboratory for Nuclear-Agricultural Sciences of Chinese Ministry of Agriculture and Zhejiang Province, Institute of Nuclear-Agricultural Sciences, Zhejiang University, 2Central Laboratory, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China *These authors contributed equally to this work Abstract: Deinococcus radiodurans is an extreme bacterium known for its high resistance to stresses including radiation and oxidants. The ability of D. radiodurans to reduce Au(III and biosynthesize gold nanoparticles (AuNPs was investigated in aqueous solution by ultraviolet and visible (UV/Vis absorption spectroscopy, electron microscopy, X-ray diffraction (XRD, dynamic light scattering (DLS, Fourier transform infrared spectroscopy (FTIR and X-ray photoelectron spectroscopy (XPS. D. radiodurans efficiently synthesized AuNPs from 1 mM Au(III solution in 8 h. The AuNPs were of spherical, triangular and irregular shapes with an average size of 43.75 nm and a polydispersity index of 0.23 as measured by DLS. AuNPs were distributed in the cell envelope, across the cytosol and in the extracellular space. XRD analysis confirmed the crystallite nature of the AuNPs from the cell supernatant. Data from the FTIR and XPS showed that upon binding to proteins or compounds through interactions with carboxyl, amine, phospho and hydroxyl groups, Au(III may be reduced to Au(I, and further reduced to Au(0 with the capping groups to stabilize the AuNPs. Biosynthesis of AuNPs was optimized with respect to the initial concentration of gold salt, bacterial growth period, solution pH and temperature. The purified AuNPs exhibited significant antibacterial activity against both Gram-negative (Escherichia coli and Gram-positive (Staphylococcus aureus bacteria by damaging their cytoplasmic membrane. Therefore, the extreme

  17. Oleanolic acid induces mitochondrial-dependent apoptosis and G0/G1 phase arrest in gallbladder cancer cells

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    Li HF

    2015-06-01

    Full Text Available Huai-Feng Li,1–3,* Xu-An Wang,1–3,* Shan-Shan Xiang,1–3,* Yun-Ping Hu,1–3 Lin Jiang,1–3 Yi-Jun Shu,1–3 Mao-Lan Li,1–3 Xiang-Song Wu,1–3 Fei Zhang,1–3 Yuan-Yuan Ye,1–3 Hao Weng,1–3 Run-Fa Bao,1–3 Yang Cao,1–3 Wei Lu,1–3 Qian Dong,1–3 Ying-Bin Liu1–3 1Department of General Surgery, 2Laboratory of General Surgery, 3Institute of Biliary Tract Disease, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai, People’s Republic of China *These authors contributed equally to this work Abstract: Oleanolic acid (OA, a naturally occurring triterpenoid, exhibits potential antitumor activity in many tumor cell lines. Gallbladder carcinoma is the most common malignancy of the biliary tract, and is a highly aggressive tumor with an extremely poor prognosis. Unfortunately, the effects of OA on gallbladder carcinoma are unknown. In this study, we investigated the effects of OA on gallbladder cancer cells and the underlying mechanism. The results showed that OA inhibits proliferation of gallbladder cancer cells in a dose-dependent and time-dependent manner on MTT and colony formation assay. A flow cytometry assay revealed apoptosis and G0/G1 phase arrest in GBC-SD and NOZ cells. Western blot analysis and a mitochondrial membrane potential assay demonstrated that OA functions through the mitochondrial apoptosis pathway. Moreover, this drug inhibited tumor growth in nude mice carrying subcutaneous NOZ tumor xenografts. These data suggest that OA inhibits proliferation of gallbladder cancer cells by regulating apoptosis and the cell cycle process. Thus, OA may be a promising drug for adjuvant chemotherapy in gallbladder carcinoma. Keywords: oleanolic acid, gallbladder carcinoma, apoptosis, cell cycle arrest, mitochondrial pathway

  18. 20(S-ginsenoside Rg3 promotes senescence and apoptosis in gallbladder cancer cells via the p53 pathway

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    Zhang F

    2015-08-01

    Full Text Available Fei Zhang,* Maolan Li,* Xiangsong Wu,* Yunping Hu, Yang Cao, Xu’an Wang, Shanshan Xiang, Huaifeng Li, Lin Jiang, Zhujun Tan, Wei Lu, Hao Weng, Yijun Shu, Wei Gong, Xuefeng Wang, Yong Zhang, Weibin Shi, Ping Dong,# Jun Gu,# Yingbin Liu#Department of General Surgery and Laboratory of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine, Institute of Biliary Tract Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China *These authors contributed equally to this work #These authors jointly directed this work Abstract: Gallbladder cancer (GBC, the most frequent malignancy of the biliary tract, is associated with high mortality and extremely poor prognosis. 20(S-ginsenoside Rg3 (20(S-Rg3 is a steroidal saponin with high pharmacological activity. However, the anticancer effect of 20(S-Rg3 in human GBC has not yet been determined. In this study, we primarily found that 20(S-Rg3 exposure suppressed the survival of both NOZ and GBC-SD cell lines in a concentration-dependent manner. Moreover, induction of cellular senescence and G0/G1 arrest by 20(S-Rg3 were accompanied by a large accumulation of p53 and p21 as a result of murine double minute 2 (MDM2 inhibition. 20(S-Rg3 also caused a remarkable increase in apoptosis via the activation of the mitochondrial-mediated intrinsic caspase pathway. Furthermore, intraperitoneal injection of 20(S-Rg3 (20 or 40 mg/kg for 3 weeks markedly inhibited the growth of xenografts in nude mice. Our results demonstrated that 20(S-Rg3 potently inhibited growth and survival of GBC cells both in vitro and in vivo. 20(S-Rg3 attenuated GBC growth probably via activation of the p53 pathway, and subsequent induction of cellular senescence and mitochondrial-dependent apoptosis. Therefore, 20(S-Rg3 may be a potential chemotherapeutic agent for GBC therapy.Keywords: gallbladder cancer, 20(S-ginsenoside Rg3, senescence, apoptosis, p53 pathway

  19. Double-blind comparison of ziprasidone and risperidone in the treatment of Chinese patients with acute exacerbation of schizophrenia

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    Hongyan Zhang

    2011-03-01

    Full Text Available Hongyan Zhang1, Huafang Li2, Liang Shu1, Niufan Gu2, Gang Wang3, Yongzhen Weng3, Shiping Xie4, Xinbao Zhang4, Ting Li5, Cui Ma5, Wei Yu6, Bruce Parsons7, Manjula Schou81Institute of Mental Health, Peking University, Beijing, China; 2Shanghai Mental Health Center, Shanghai, China; 3Capital Medical University, Beijing An Ding Hospital, Beijing, China; 4Nanjing Brain Hospital, Nanjing, China; 5Guangzhou Brain Hospital, Guangzhou, China; 6Pfizer China, Beijing, China; 7Pfizer Inc, New York, NY, USA; 8Pfizer Australia, Sydney, AustraliaBackground: The aim of the study was to evaluate the efficacy and safety of ziprasidone versus risperidone in Chinese subjects with acute exacerbation of schizophrenia.Methods: In patients meeting the Chinese Classification of Mental Disorders criteria for schizophrenia and with a Positive and Negative Syndrome Scale (PANSS total score ≥60 were randomly assigned to six weeks of double-blind treatment with ziprasidone 40–80 mg twice daily or risperidone 1–3 mg bid, flexibly dosed. Noninferiority was demonstrated if the upper limit of the two-sided 95% confidence interval (CI for the difference in PANSS total score improvement from baseline in the evaluable population was smaller than the prespecified noninferiority margin of 10 units.Results: The intent-to-treat population comprised 118 ziprasidone-treated and 121 risperidone-treated subjects. Improvement (reduction from baseline to week 6 in PANSS total score was (-35.6 [95% CI: -38.6, -32.6] for ziprasidone and (-37.1 [95% CI: -39.9, -34.4] for risperidone. Noninferiority was demonstrated in the evaluable population with a difference score of 1.5 [95% CI: -2.5, 5.5]. Mean prolactin levels decreased at week 6 compared with baseline for ziprasidone (-3.5 ng/mL, but significantly increased for risperidone (61.1 ng/mL; P < 0.001. More risperidone-treated subjects (14.9% than ziprasidone-treated subjects (4.2% reported weight gain ≥7%. Akathisia and somnolence in

  20. PREFACE: Joint European Magnetic Symposia - JEMS 2010

    Science.gov (United States)

    Spałek, Jozef

    2011-07-01

    łekChairman of JEMS 2010 Symposia 1. Plenary, Semi-plenary, Tutorials 2. Magnetization Processes Spin Excitations and Ultrafast DynamicsCoordinator: Andrzej Maziewski (Bialystok) 3. Hard Magnetic Materials and MagnetocaloricsCoordinator: Henryk Figiel (Kraków) 4. Magnetic HydridesCoordinators: Ladislav Havela (Praha), Zbigniew Tarnawski (Kraków) 5. Interface of Magnetic Thin FilmsCoordinators: Jürgen Fassbender (Dresden), N-T H Kim-Ngan (Kraków) 6. Magnonic CrystalsCoordinators: Bahram Djafari-Rouhani (Lille), Henryk Puszkarski (Poznan) 7. Magnetism of Metals, Alloys, and IntermetallicsCoordinator: Andrzej Szytula (Kraków) 8. Molecular MagnetismCoordinators: Stephen Blundell (Oxford), Maria Balanda (Kraków) 9. Magnetooptics of NanomagnetsCoordinators: Kamil Postava (Ostrava), Marek Kisielewski (Bialystok) 10. NanomagnetismCoordinators: Marek Przybylski (Halle), Jürgen Kirschner (Halle) 11. Other topics - Biomagnetism, Domain Walls, InstrumentationCoordinator: Henryk Figiel (Kraków) 12. Magnetic Perovskites and MultiferroicsCoordinator: Henryk Szymczak (Warszawa) 13. Magnetic Semiconductors and InsulatorsCoordinators: Klaus Baerner (Göttingen), Tadeusz Gron (Katowice) 14. Magnetic Shape Memory Effects and Related PhenomenaCoordinators: Oliver Gutfleisch (Dresden), Sebastian Fähler (Dresden) 15. Soft Magnetic MaterialsCoordinators: Julian González (San Sebastian), Krzysztof Kulakowski (Kraków) 16. SpintronicsCoordinator: Maciej Sawicki (Warszawa) 17. Strongly Correlated Electron Systems, Magnetism and SuperconductivityCoordinator: Andrzej Slebarski (Katowice) The next Joint European Magnetic Symposia, JEMS 2012, will be held in Parma, Italy, 9-14 September 2012.www.jems2012.itCo-Chairs:Franca Albertini, Institute of Materials for Electronics and Magnetism (IMEM), CNR, ParmaRoberto De Renzi, Department of Physics, University of Parma

  1. [Epizootiological and parasitological status of the flocks at a poultry combine].

    Science.gov (United States)

    Kolev, V; Markarian, M; Genchev, G; Donev, A; Tsvetkov, S

    1976-01-01

    A comprehensive epizootiologic study has been carried out at one of the large poultry dressing combines in this country. Results have shown that the part played by infections as against the remaining diseases established in the various technologic categories is as follows: 9 to 23.8 per cent in growing parents; 16.0 to 24.6 per cent in adult parents; and 4.8 to 13.4 per cent in broilers. So far as parasitic diseases are concerned the respective figures are 3.2 to 9.9 per cent, 3.0 to 3.3. per cent, and 2.9 to 3.0 to per cent. The import of birds from France and England intended for satisfying the needs of the poultry dressing combine in Roussé has contributed to the introduction of infections which have later on assumed an epizootic course, such as infections encephalomyelitis, infectious bronchitis, and Marek' disease. The epizootic status has been aggravated with the development of a number of diseases already existing in this country--fowl pox, lymphoid leukosis, chronic respiratory disease, salmonellosis, and above all infections caused by the so-called occasionally pathogenic agents--coli organisms, staphylococci, and Pseudomonas. Of the parasitic diseases only coccidiosis has developed, being caused by a variety of species: Eimeria acervulina, Eimeria necatrix, Eimeria maxima, Eimeria muvati and Eimeria tenella. The absence of helminth infections is due to the routinely adopted technological practice of raising birds in confinement and the strict veterinary control and guard. On the basis of the results obtained and the conclusions drawn some more effective prophylactic measures are suggested correcting and supplementing the existing prophylactic programme.

  2. Construction of somatic and motor skills of people training taekwondo WTF

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    Cieslicka Miroslawa.

    2012-10-01

    Full Text Available The purpose of this study was to analyze in terms of somatic and motor skills young people from high school in Bydgoszcz, taekwondo class profile. The object of the study were participants of Interschool Student Sports Club "Piętnastka" training this sport. The study included 36 patients aged 14.5, 15.5 and 16.5 years. Measured the height and body weight were and done the International Physical Fitness Test which included the following tests: long jump, hang on bent arms (girls or rising in the overhang on the stick (boys, shuttles run 4 x 10 m moving pads, traces of the lying and the slope in front trunk. The results were analyzed by gender and age, and tested the correlation between pairs of traits. It also examined how young people from their own studies compare to peers in the regional study conducted in 2005 by Marek Napierala [3]. After analyzing the test results the following conclusions: 1 Boys from our studies are characterized by a greater height and weight and achieve better results in all samples IPFT than girls; 2 Physical fitness increases with age - the best results attained IPFT students from the oldest age group (16.5 years; 3 Good results in other trials provide good performance in the course of 4 x 10 m; 4 Boys who train taekwondo in IPFT perform better than their peers from Kujawsko-Pomorskie in all age groups; 5 The sum of the calculated points obtained according to the scale T for girls is higher for taekwondo. However in not all trials, the girls from our studies performed better.

  3. Therapy of psoriasis with narrowband ultraviolet-B light influences plasma concentrations of MMP-2 and TIMP-2 in patients

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    Głażewska EK

    2016-10-01

    Full Text Available Edyta Katarzyna Głażewska,1 Marek Niczyporuk,1 Sławomir Ławicki,2 Maciej Szmitkowski,2 Monika Zajkowska,2 Grażyna Ewa Będkowska,3 Andrzej Przylipiak1 1Department of Esthetic Medicine, 2Department of Biochemical Diagnostics, 3Department of Haematological Diagnostics, Medical University, Białystok, Poland Background: Matrix metalloproteinases (MMPs, which show a significant ability to cleave the components of extracellular matrix, and tissue inhibitors of metalloproteinases (TIMPs, which slow down the activity of those enzymes, may be implicated in the pathogenesis and spread of psoriatic disease. This study aims to analyze plasma levels of MMP-2 and TIMP-2 in plaque psoriasis patients before and after the course of narrowband ultraviolet-B (NBUVB therapy with respect to disease advancement. Patients and methods: A total of 49 patients suffering from plaque psoriasis and 40 healthy volunteers were enrolled into the study. Plasma levels of MMP-2 and TIMP-2 were determined using enzyme-linked immunosorbent assay, while Psoriasis Area and Severity Index (PASI was used to define the disease advancement. Results: The results showed increased plasma levels of MMP-2 and TIMP-2, but this change was significant only in case of MMP-2 in total psoriatic group compared to healthy subjects. Moreover, there was an increase in the concentrations of chosen factors with an increase in the severity of the disease. The NBUVB therapy causes a decline in the concentration of the analyzed enzyme and its inhibitor, although this change was statistically significant in the total psoriatic group only in case of MMP-2. There was also a positive correlation between MMP-2, TIMP-2, and PASI score value. Conclusion: Our study highlights a possible important role of MMP-2 in the activity of psoriasis and clearance of disease symptoms. Moreover, plasma MMP-2 seems to be a valuable psoriasis biomarker. Keywords: gelatinase A, matrix metalloproteinases, tissue inhibitor of

  4. Parcelling activity of the National Bank for Agriculture in interwar Poland in the years 1924-1929

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    Mirosław Kłusek

    2009-01-01

    Full Text Available Scientific literature related to the problem in focus is exceptionally poor. The only book publication concerns the National Bank for Agriculture in the twenty-year interwar period is book position of Marek Nowak’s authorship [Nowak 1988]. But, on account of its modest range, bank agrarian activity has been treated too generally. In this publication author’s opinion is that this activity needs deeper analysis. Parcelling is an economic process which took part in Poland and lasted from the moment of grant freehold. It ran with special intensification towards the end of XIX century and at the beginning of XX century. In inter-war period, on account of source of parcelled soil, parcellation was divided into private and governmental. Governmental parcellation, which related to public property, included lands by Regional District Councils and territories included by military settlement. However, lands allocated by the National Bank for Agriculture and by individual people made private parcellation. The beginning of the National Bank for Agriculture’s agrarian activity’ was enabled by Poland President’s directive from 1924. One of the main tasks put against NBA was support: parcellation and settlement, agricul-tural regulations by landed estates purchase for parcelling aims and giving long-term credits for land purchase. However, according to status, the National Bank for Agriculture was able to parcel out landed properties, both purchased for private property and entrusted to commission state. Tasks put against parcellation conducted by the National Bank for Ag-riculture were not carried out in a satisfactory way. The Bank’s activity did not contribute to shopping the process of farms fragmentation at serious level and process of agrarian overpopulation’s growth among fewer ownership. Similarly, it also was not an essential source of establishing new farms capable of competing with vast-land ownership.

  5. Nowe wymiary tożsamości – media, kultura popularna, rzeczywistość cyfrowa

    Directory of Open Access Journals (Sweden)

    Wojciech Baluch

    2016-06-01

    Full Text Available The text concentrates on the issue of identity and its transformations, driven by the spread of media and digital culture. In the first part it presents three canonic proposals for reflections on virtual identity. Firstly, reflections on the communication dimension of identity derived from Martin Buber’s philosophy of dialog. Secondly, the concept of “ontological shift” as suggested by Marek Krajewski, who sees in it the remedy for the lack of a real dimension of many virtual contacts. Thirdly, the issues of the integrity of the individual and the fluidity of modern reality in the approaches proposed by Wolfgang Welsh, Anthony Giddens, and Zygmunt Bauman. The analytical part contains an analysis of the important aspects of the notion of identity. The first is the issue of the subjectivity of an utterance and its source, which will be discussed using the example of a play based on texts that adapted from Internet blogs. The second issue is an attempt to answer the question posed by Sherry Turkle of whether if it is possible to kill someone virtually. The point of reference for the search for a solution to this issue is the popular computer game “Vampire”.The last aspect has to do with celebrity identity in the media world. This concerns the phenomenon of celebrities in the pragmatic dimension as a model strategy of behaviour in the world, in which the boundary between privacy and public space has been blurred. On the basis of these analyses, which cover merely a small part of human experience, the author proposes a new methodological approach to perceiving and analysing aspects of identity revealed through the confrontation with the new virtual reality.

  6. Clinical aspects of immunosuppression in poultry.

    Science.gov (United States)

    Hoerr, Frederic J

    2010-03-01

    Chickens, turkeys, and other poultry in a production environment can be exposed to stressors and infectious diseases that impair innate and acquired immunity, erode general health and welfare, and diminish genetic and nutritional potential for efficient production. Innate immunity can be affected by stressful physiologic events related to hatching and to environmental factors during the first week of life. Exposure to environmental ammonia, foodborne mycotoxins, and suboptimal nutrition can diminish innate immunity. Infectious bursal disease (IBD), chicken infectious anemia (CIA), and Marek's disease (MD) are major infectious diseases that increase susceptibility to viral, bacterial, and parasitic diseases and interfere with acquired vaccinal immunity. A shared feature is lymphocytolytic infection capable of suppressing both humoral and cell-mediated immune functions. Enteric viral infections can be accompanied by atrophic and depleted lymphoid organs, but the immunosuppressive features are modestly characterized. Some reoviruses cause atrophy of lymphoid organs and replicate in blood monocytes. Enteric parvoviruses of chickens and turkeys merit further study for immunosuppression. Hemorrhagic enteritis of turkeys has immunosuppressive features similar to IBD. Other virulent fowl adenoviruses have immunosuppressive capabilities. Newcastle disease can damage lymphoid tissues and macrophages. Avian pneumovirus infections impair the mucociliary functions of the upper respiratory tract and augment deeper bacterial infections. Recognition of immunosuppression involves detection of specific diseases using diagnostic tests such as serology, etiologic agent detection, and pathology. Broader measurements of immunosuppression by combined noninfectious and infectious causes have not found general application. Microarray technology to detect genetic expression of immunologic mediators and receptors offers potential advances but is currently at the developmental state. Control

  7. Disruption of a Quorum Sensing mechanism triggers tumorigenesis: a simple discrete model corroborated by experiments in mammary cancer stem cells

    Directory of Open Access Journals (Sweden)

    Kirnasovsky Oleg U

    2010-04-01

    Full Text Available Abstract Background The balance between self-renewal and differentiation of stem cells is expected to be tightly controlled in order to maintain tissue homeostasis throughout life, also in the face of environmental hazards. Theory, predicting that homeostasis is maintained by a negative feedback on stem cell proliferation, implies a Quorum Sensing mechanism in higher vertebrates. Results Application of this theory to a cellular automata model of stem cell development in disrupted environments shows a sharply dichotomous growth dynamics: maturation within 50-400 cell cycles, or immortalization. This dichotomy is mainly driven by intercellular communication, low intensity of which causes perpetual proliferation. Another driving force is the cells' kinetic parameters. Reduced tissue life span of differentiated cells results in uncontrolled proliferation. Model's analysis, showing that under the Quorum Sensing control, stem cell fraction within a steady state population is fixed, is corroborated by experiments in breast carcinoma cells. Experimental results show that the plating densities of CD44+ cells and of CD44+/24lo/ESA+ cells do not affect stem cell fraction near confluence. Conclusions This study suggests that stem cell immortalization may be triggered by reduced intercellular communication, rather than exclusively result from somatic evolution, and implies that stem cell proliferation can be attenuated by signal manipulation, or enhanced by cytotoxics targeted to differentiated cells. In vivo verification and identification of the Quorum Sensing mediating molecules will pave the way to a higher level control of stem cell proliferation in cancer and in tissue engineering. Reviewers This article was reviewed by Glenn Webb and Marek Kimmel.

  8. A retrospective PCR investigation of avian Orthoreovirus, chicken infectious anemia and fowl Aviadenovirus genomes contamination in commercial poultry vaccines in Brazil

    Directory of Open Access Journals (Sweden)

    P.R. Barrios

    2012-02-01

    Full Text Available Vacinas avícolas vivas comerciais produzidas entre 1991 e 2005 foram examinadas para a presença de genomas dos vírus da anemia infecciosa das galinhas (Gyrovirus CAV, da hepatite por corpúsculo de inclusão (Aviadenovirus FAdV e da artrite viral/síndrome da má absorção (Orthoreovirus aviário ARV. Vinte e seis partidas de vacinas vivas liofilizadas de oito fabricantes com lacre original foram examinadas. As extrações de DNA e PCR de CAV e FAdV, e de RNA e RT-PCR para ARV, foram descritas previamente. Contaminações triplas de ARV, CAV e FAdV foram detectadas em vacinas de mesmo fabricante, produzidas em 1991 e 1992 contra a doença de Newcastle (DN, e para a encefalomielite aviária, produzida em 1994. ARV e CAV em co-infecção foram encontrados em vacinas contra a doença de Marek liofilizadas produzidas em 1996 por dois fabricantes diferentes. Genoma de ARV foi detectado em vacinas contra a bronquite infecciosa de setembro e dezembro de 1998, doença infecciosa bursal, de dezembro de 1998 e DN de janeiro de 1998. Três dos oito fabricantes apresentaram vacinas com contaminação e cinco nunca apresentaram vacinas contaminadas. Nenhuma vacina produzida a partir de 2001 apresentou contaminação. Cogita-se um papel epidemiológico para vacinas vivas, como fonte de infecção para ARV, CAV e FAdV e, potencialmente determinante da atual alta disseminação destes.

  9. Gp85 genetic diversity of avian leukosis virus subgroup J among different individual chickens from a native flock.

    Science.gov (United States)

    Li, Yang; Fu, Jiayuan; Cui, Shuai; Meng, Fanfeng; Cui, Zhizhong; Fan, Jianhua; Chang, Shuang; Zhao, Peng

    2017-05-01

    To compare the genetic diversity and quasispecies evolution of avian leukosis virus (ALV) among different individuals, 5 chickens, raised in Shandong Provice of China, were randomly selected from a local chicken flock associated with serious tumor cases. Blood samples were collected and inoculated into chicken embryo fibroblast and DF-1 cell lines for virus isolation and identification, respectively, of Marek's disease virus (MDV), reticuloendotheliosis virus (REV), and ALV. Five strains of ALV subgroup J (ALV-J) were identified, and the gp85 gene from each strain was amplified and cloned. For each strain, about 20 positive clones of gp85 gene were selected for sequence analyses and the variability of the quasispecies of the 5 strains was compared. The results showed that the nuclear acid length of gp85 gene of 5 ALV-J isolates is 921 bp, 921 bp, 924 bp, 918 bp, and 912 bp respectively, and amino acid homologies of different gp85 clones from the 5 ALV-J strains were 99.3 to 100%, 99.3 to 100%, 99.4 to 100%, 98.4 to 100%, 99.0 to 100%, respectively. The proportions of dominant quasispecies were 65.0%, 85.0%, 85.0%, 50.0%, 84.2%, respectively, and homology of the gp85 among these dominant quasispecies was 89.2 to 92.5%. These data demonstrated the composition of the ALV-J quasispecies varied among infected individuals even within the same flock, and the dominant quasispecies continued to evolve both for their proportion and gene mutation. © 2016 Poultry Science Association Inc.

  10. Nonlinear Dynamics, Chaotic and Complex Systems

    Science.gov (United States)

    Infeld, E.; Zelazny, R.; Galkowski, A.

    2011-04-01

    Part I. Dynamic Systems Bifurcation Theory and Chaos: 1. Chaos in random dynamical systems V. M. Gunldach; 2. Controlling chaos using embedded unstable periodic orbits: the problem of optimal periodic orbits B. R. Hunt and E. Ott; 3. Chaotic tracer dynamics in open hydrodynamical flows G. Karolyi, A. Pentek, T. Tel and Z. Toroczkai; 4. Homoclinic chaos L. P. Shilnikov; Part II. Spatially Extended Systems: 5. Hydrodynamics of relativistic probability flows I. Bialynicki-Birula; 6. Waves in ionic reaction-diffusion-migration systems P. Hasal, V. Nevoral, I. Schreiber, H. Sevcikova, D. Snita, and M. Marek; 7. Anomalous scaling in turbulence: a field theoretical approach V. Lvov and I. Procaccia; 8. Abelian sandpile cellular automata M. Markosova; 9. Transport in an incompletely chaotic magnetic field F. Spineanu; Part III. Dynamical Chaos Quantum Physics and Foundations Of Statistical Mechanics: 10. Non-equilibrium statistical mechanics and ergodic theory L. A. Bunimovich; 11. Pseudochaos in statistical physics B. Chirikov; 12. Foundations of non-equilibrium statistical mechanics J. P. Dougherty; 13. Thermomechanical particle simulations W. G. Hoover, H. A. Posch, C. H. Dellago, O. Kum, C. G. Hoover, A. J. De Groot and B. L. Holian; 14. Quantum dynamics on a Markov background and irreversibility B. Pavlov; 15. Time chaos and the laws of nature I. Prigogine and D. J. Driebe; 16. Evolutionary Q and cognitive systems: dynamic entropies and predictability of evolutionary processes W. Ebeling; 17. Spatiotemporal chaos information processing in neural networks H. Szu; 18. Phase transitions and learning in neural networks C. Van den Broeck; 19. Synthesis of chaos A. Vanecek and S. Celikovsky; 20. Computational complexity of continuous problems H. Wozniakowski; Part IV. Complex Systems As An Interface Between Natural Sciences and Environmental Social and Economic Sciences: 21. Stochastic differential geometry in finance studies V. G. Makhankov; Part V. Conference Banquet

  11. BG1 has a major role in MHC-linked resistance to malignant lymphoma in the chicken.

    Science.gov (United States)

    Goto, Ronald M; Wang, Yujun; Taylor, Robert L; Wakenell, Patricia S; Hosomichi, Kazuyoshi; Shiina, Takashi; Blackmore, Craig S; Briles, W Elwood; Miller, Marcia M

    2009-09-29

    Pathogen selection is postulated to drive MHC allelic diversity at loci for antigen presentation. However, readily apparent MHC infectious disease associations are rare in most species. The strong link between MHC-B haplotype and the occurrence of virally induced tumors in the chicken provides a means for defining the relationship between pathogen selection and MHC polymorphism. Here, we verified a significant difference in resistance to gallid herpesvirus-2 (GaHV-2)-induced lymphomas (Marek's disease) conferred by two closely-related recombinant MHC-B haplotypes. We mapped the crossover breakpoints that distinguish these haplotypes to the highly polymorphic BG1 locus. BG1 encodes an Ig-superfamily type I transmembrane receptor-like protein that contains an immunoreceptor tyrosine-based inhibition motif (ITIM), which undergoes phosphorylation and is recognized by Src homology 2 domain-containing protein tyrosine phosphatase (SHP-2). The recombinant haplotypes are identical, except for differences within the BG1 3'-untranslated region (3'-UTR). The 3'-UTR of the BG1 allele associated with increased lymphoma contains a 225-bp insert of retroviral origin and showed greater inhibition of luciferase reporter gene translation compared to the other allele. These findings suggest that BG1 could affect the outcome of GaHV-2 infection through modulation of the lymphoid cell responsiveness to infection, a condition that is critical for GaHV-2 replication and in which the MHC-B haplotype has been previously implicated. This work provides a mechanism by which MHC-B region genetics contributes to the incidence of GaHV-2-induced malignant lymphoma in the chicken and invites consideration of the possibility that similar mechanisms might affect the incidence of lymphomas associated with other oncogenic viral infections.

  12. Development of a chick bioassay for determination of infectivity of viral pathogens in poultry litter.

    Science.gov (United States)

    Islam, A F M F; Walkden-Brown, S W; Groves, P J; Wells, B

    2013-01-01

    To develop a chicken bioassay to detect infective viral pathogens in poultry litter and to determine the effects of type of chicken and age of exposure, as well as the effect of simulated litter transportation, on the level of viral infectivity detected. A 5 × 2 × 2 factorial design, plus negative controls. Five chicken litters, including two with deliberate contamination (one transported and one not), two chicken types (specific-pathogen-free (SPF) Leghorns and Cobb broilers) and two ages at initial exposure (days 1 and 8). Two replicates of each treatment combination. The 10 chickens in each of 22 isolators were either exposed (20 isolators) or not (2 isolators) to 8 L of previously used or deliberately contaminated poultry litter in two deep scratch trays. At day 35 post-exposure, sera were assayed for antibodies against chicken anaemia virus (CAV), infectious bronchitis virus (IBV), infectious bursal disease virus (IBDV), Newcastle disease virus (NDV) and fowl adenovirus (FAV). Spleen samples were tested for Marek's disease virus (MDV) using real-time polymerase chain reaction. The bioassay detected CAV, IBDV and FAV, but not NDV, IBV or MDV, in chickens exposed to infected litters. Infection in SPF chickens was detected with greater sensitivity than in the broiler chickens. Sensitivity increased with age at exposure in broiler but not SPF chickens. Simulated transportation for 24 h had little effect on pathogen detection. A bioassay based on the exposure of day-old SPF chickens to poultry litter and measurement of seroconversion at day 35 post-exposure is a useful semi-quantitative assay for viral infectivity in poultry litter, with overnight transportation of litter having little effect on the level of viral infectivity detected. This bioassay has applications in research on litter treatment protocols. © 2013 The Authors. Australian Veterinary Journal © 2013 Australian Veterinary Association.

  13. Expression patterns of endogenous avian retrovirus ALVE1 and its response to infection with exogenous avian tumour viruses.

    Science.gov (United States)

    Hu, Xuming; Zhu, Wenqi; Chen, Shihao; Liu, Yangyang; Sun, Zhen; Geng, Tuoyu; Song, Chengyi; Gao, Bo; Wang, Xiaoyan; Qin, Aijian; Cui, Hengmi

    2017-01-01

    Endogenous retroviruses (ERVs) are genomic elements that are present in a wide range of vertebrates and have been implicated in a variety of human diseases, including cancer. However, the characteristic expression patterns of ERVs, particularly in virus-induced tumours, is not fully clear. DNA methylation was analysed by bisulfite pyrosequencing, and gene expression was analysed by RT-qPCR. In this study, we first found that the endogenous avian retrovirus ALVE1 was highly expressed in some chicken tissues (including the heart, bursa, thymus, and spleen) at 2 days of age, but its expression was markedly decreased at 35 days of age. In contrast, the CpG methylation level of ALVE1 was significantly lower in heart and bursa at 2 days than at 35 days of age. Moreover, we found that the expression of ALVE1 was significantly inhibited in chicken embryo fibroblast cells (CEFs) and MSB1 cells infected with avian leukosis virus subgroup J (ALVJ) and reticuloendotheliosis virus (REV) at the early stages of infection. In contrast, the expression of the ALVE1 env gene was significantly induced in CEFs and MSB1 cells infected with Marek's disease virus (MDV). However, the methylation and expression levels of the ALVE1 long terminal repeat (LTR) did not show obvious alterations in response to viral infection. The present study revealed the expression patterns of ALVE1 in a variety of chicken organs and tissues and in chicken cells in response to avian tumour virus infection. These findings may be of significance for understanding the role and function of ERVs that are present in the host genome.

  14. Effects of feed-borne Fusarium mycotoxins with or without yeast cell wall adsorbent on organ weight, serum biochemistry, and immunological parameters of broiler chickens.

    Science.gov (United States)

    Li, Z; Yang, Z B; Yang, W R; Wang, S J; Jiang, S Z; Wu, Y B

    2012-10-01

    The objectives of the present study were to investigate the toxicity of feed-borne Fusarium mycotoxins on organ weight, serum biochemistry, and immunological parameters of broiler chickens and to evaluate the efficacy of yeast cell wall adsorbent in preventing mycotoxin-induced adverse effects. In total, 300 one-day-old vaccinated (Marek's disease and infectious bronchitis) Arbor Acres broiler chickens (mixed sex) were randomly divided into 3 treatments (5 repetitions per treatment) and fed basal diet and naturally contaminated diets with or without yeast cell wall adsorbent. Treatments were control, naturally contaminated diet (NCD; aflatoxin, 102.08 mg/kg; zearalenone, 281.92 mg/kg; fumonisin, 5,874.38 mg/kg; deoxynivalenol, 2,038.96 mg/kg), and NCD + 2 g/kg of yeast cell wall adsorbent (NCDD). The test included 2 phases: d 0-21 and d 22-42. At 42 d, broilers fed contaminated diets without yeast cell wall adsorbent had higher (P effect on the relative weight of the liver and spleen at 21 d, relative weight of the bursa of Fabricius and thymus at 42 d, antibody titers of Newcastle disease at both 28 d and 42 d, and splenic mRNA expression of IL-1β, IL-6, and IFN-γ at 42 d. It is suggested that feeding a naturally contaminated diet for 42 d might result in a deleterious effect in broiler chickens, and addition of 2 g/kg of yeast cell wall enterosorbent can partly neutralize the detrimental effects of the naturally contaminated feed.

  15. Isolation and purification of Gallid herpesvirus 2 strains currently distributed in Japan.

    Science.gov (United States)

    Machida, Yuka; Murata, Shiro; Matsuyama-Kato, Ayumi; Isezaki, Masayoshi; Taneno, Akira; Sakai, Eishi; Konnai, Satoru; Ohashi, Kazuhiko

    2017-01-20

    Gallid herpesvirus 2 (GaHV-2) causes malignant lymphomas in chickens (Marek's disease, MD). Although MD is controlled through vaccination efforts, field isolates of GaHV-2 have increased in virulence worldwide and even cause MD in vaccinated chickens. GaHV-2 strains are classified into four categories (mild, virulent, very virulent and very virulent +) based on the virulence exhibited in experimental infection in unvaccinated or MD-vaccinated susceptible chickens. Although MD cases are sporadically reported in Japan, the recent field strains of GaHV-2 in Japan have not been characterized. During isolation of recent field strains by using primary chicken kidney cell cultures, a method classically used for GaHV-2 isolation, vaccine strains were simultaneously isolated. Therefore, it is necessary to separate vaccine strains to characterize the virulence and pathogenicity of the GaHV-2 strains currently distributed in Japan. In this study, we prepared cell suspensions from the spleens of MD-symptomatic chickens, inoculated day-old-chicks and isolated GaHV-2 strains by primary chicken kidney cell cultures at 2-3 weeks post inoculation. The isolated strains were passaged several times on chicken embryo fibroblast cells, and PCR analysis revealed that the isolated strains were not contaminated with vaccine strains. Moreover, the contaminant vaccine strains were completely removed by the purification of plaques observed in chicken kidney cells. These procedures are necessary to isolate GaHV-2 field strains from vaccine strains in order to carry out future studies to characterize these strains and glean insights into GaHV-2 virulence and pathogenicity.

  16. The use of quartz crystal microbalance with dissipation (QCM-D for studying nanoparticle-induced platelet aggregation

    Directory of Open Access Journals (Sweden)

    Santos-Martinez MJ

    2012-01-01

    Full Text Available Maria Jose Santos-Martinez1–3, Iwona Inkielewicz-Stepniak1,4, Carlos Medina1, Kamil Rahme5,6, Deirdre M D'Arcy1, Daniel Fox3, Justin D Holmes3,5, Hongzhou Zhang3, Marek Witold Radomski3,51School of Pharmacy and Pharmaceutical Sciences, 2School of Medicine, 3Center for Research on Adaptive Nanostructures and Nanodevices, Trinity College Dublin, Dublin, Ireland; 4Department of Medicinal Chemistry, Medical University of Gdansk, Gdansk, Poland; 5Materials and Supercritical Fluids Group, Department of Chemistry and the Tyndall National Institute, University College Cork, Cork, Ireland; 6Department of Sciences, Faculty of Natural and Applied Science, Notre Dame University, Zouk Mosbeh, LebanonAbstract: Interactions between blood platelets and nanoparticles have both pharmacological and toxicological significance and may lead to platelet activation and aggregation. Platelet aggregation is usually studied using light aggregometer that neither mimics the conditions found in human microvasculature nor detects microaggregates. A new method for the measurement of platelet microaggregation under flow conditions using a commercially available quartz crystal microbalance with dissipation (QCM-D has recently been developed. The aim of the current study was to investigate if QCM-D could be used for the measurement of nanoparticle-platelet interactions. Silica, polystyrene, and gold nanoparticles were tested. The interactions were also studied using light aggregometry and flow cytometry, which measured surface abundance of platelet receptors. Platelet activation was imaged using phase contrast and scanning helium ion microscopy. QCM-D was able to measure nanoparticle-induced platelet microaggregation for all nanoparticles tested at concentrations that were undetectable by light aggregometry and flow cytometry. Microaggregates were measured by changes in frequency and dissipation, and the presence of platelets on the sensor surface was confirmed and imaged by

  17. Association of low serum aluminum level with mortality in hemodialysis patients

    Directory of Open Access Journals (Sweden)

    Hsu CW

    2016-09-01

    Full Text Available Ching-Wei Hsu,1–3 Cheng-Hao Weng,1–3 Cheng-Chia Lee,1–3 Dan-Tzu Lin-Tan,1–3 Kuan-Hsing Chen,1–3 Tzung-Hai Yen,1–3 Wen-Hung Huang1–3 1Department of Nephrology, Division of Clinical Toxicology, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China; 2Department of Nephrology, Division of Clinical Toxicology, Linkou Medical Center, Taoyuan, Taiwan, Republic of China; 3Department of Medicine, Chang Gung University College of Medicine, Taoyuan, Taiwan, Republic of China Background: The National Kidney Foundation–Kidney Disease Outcomes Quality Initiative recommends that the serum aluminum level (SAL should be below 20 µg/L for patients with maintenance hemodialysis (MHD. However, serum aluminum may have toxic effects on MHD patients even when it is in the apparently acceptable range (below 20 µg/L.Methods: The Medical Ethics Committee approved this study. Initially, 954 MHD patients in dialysis centers were recruited. A total of 901 patients met the inclusion criteria and were followed-up for 1 year. Patients were stratified by SAL into four equal-sized groups: first quartile (<6 µg/L, second quartile (6–9 µg/L, third quartile (9–13 µg/L, and fourth quartile (>13 µg/L. Demographic, biochemical, and dialysis-related data were obtained for analyses. A linear regression model was applied to identify factors associated with SAL. Cox proportional hazard model was used to determine the significance of variables in prediction of mortality.Results: Only 9.3% of MHD patients had SALs of 20 µg/L or more. At the end of the follow-up, 54 patients (6% died, and the main cause of death was cardiovascular disease. Kaplan–Meier survival analysis showed that patients in the fourth SAL quartile had higher mortality than those in the first SAL quartile (log rank test, χ2=13.47, P=0.004. Using the first quartile as reference, Cox multivariate analysis indicated that patients in the third quartile (hazard ratio =1.31, 95% confidence

  18. AirBase - A database of 160,000 aerial photos of Greenland 1930-1980s

    Science.gov (United States)

    Korsgaard, Niels; Weng, Willy L.; Kjær, Kurt H.

    2017-04-01

    Beginning in the 1930s Danish survey agencies and US military organizations conducted large-scale aerial photograph surveys of Greenland for mapping purposes (1), eventuating in the recording of more than 160,000 photographs. Glaciological researchers have used this amazing resource of multi-decadal observations of the Greenlandic cryosphere for many decades (e.g. (2), (3), (4)). In recent years this information has been synthesized with modern remote sensing data resulting in a range of published research and data sets ((5), (6), (7), (8)). Today, the historical aerial photographs are stored at the SDFE (Agency for Data Supply and Effiency), the successor agency for the institutions doing the surveying and mapping of Greenland where the material is accessible to researchers and general public alike. The digitized flightline maps and databases necessary for the creation of this data for this work was made available by the SDFE, and it the past and present work with this database we present here. Based on digitized flight line maps, the database contains geocoded metadata such as recording dates, camera and film roll canister, connecting the database with the analog archive material. Past work concentrated on bulk digitization, while the focus of the current work is to improve positional accuracy, completeness, and refinements for web publication. (1) Nielsen, A., Olsen, J. & Weng, W. L. Grønlands opmåling og kortlægning. Landinspektøren 37 (1995). (2) Weidick A. Frontal variations at Upernaviks Isstrøm in the last 100 years. Medd. fra Dansk Geol. Forening. Vol. 14 (1958. (3) Bauer, A., Baussart, M., Carbonnell, M., Kasser, P. Perroud, P. & Renaud, A. Missions aériennes de reconnaissance au Groenland 1957-1958. Observations aériennes et terrestres, exploitation des photographies aériennes, détermination des vitesses des glaciers vêlant dans Disko Bugt et Umanak Fjord. Meddelelser om Grønland 173(3) (1968a. (4) Rignot, E. Box, J.E., Burgess, E. & Hanna, E

  19. Actigraphy-based sleep estimation in adolescents and adults: a comparison with polysomnography using two scoring algorithms

    Directory of Open Access Journals (Sweden)

    Quante M

    2018-01-01

    Full Text Available Mirja Quante,1–3 Emily R Kaplan,2 Michael Cailler,2 Michael Rueschman,2 Rui Wang,2–5 Jia Weng,2 Elsie M Taveras,3,5,6 Susan Redline2,3,7 1Department of Neonatology, University of Tuebingen, Tuebingen, Germany; 2Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women’s Hospital, Boston, MA, USA; 3Harvard Medical School, Boston, MA, USA; 4Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA; 5Department of Population Medicine, Harvard Medical School and The Harvard Pilgrim Health Care Institute, Boston, MA, USA; 6Division of General Academic Pediatrics, Department of Pediatrics, MassGeneral Hospital for Children, Boston, MA, USA; 7Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA Objectives: Actigraphy is widely used to estimate sleep–wake time, despite limited information regarding the comparability of different devices and algorithms. We compared estimates of sleep–wake times determined by two wrist actigraphs (GT3X+ versus Actiwatch Spectrum [AWS] to in-home polysomnography (PSG, using two algorithms (Sadeh and Cole–Kripke for the GT3X+ recordings.Subjects and methods: Participants included a sample of 35 healthy volunteers (13 school children and 22 adults, 46% male from Boston, MA, USA. Twenty-two adults wore the GT3X+ and AWS simultaneously for at least five consecutive days and nights. In addition, actigraphy and PSG were concurrently measured in 12 of these adults and another 13 children over a single night. We used intraclass correlation coefficients (ICCs, epoch-by-epoch comparisons, paired t-tests, and Bland–Altman plots to determine the level of agreement between actigraphy and PSG, and differences between devices and algorithms.Results: Each actigraph showed comparable accuracy (0.81–0.86 for sleep–wake estimation compared to PSG. When analyzing data from the GT3X+, the Cole–Kripke algorithm was more

  20. EDITORIAL: The Fifth International Workshop and Summer School on Plasma Physics

    Science.gov (United States)

    2006-04-01

    , Russia, the US, China, South Korea and India (as of March 2006). It will take several years to accomplish this important task. There is no doubt that the success depends not only on funding but also on enthusiastic people willing to contribute with their skills and knowledge. Young scientists and engineers must be enrolled to the programme and trained in various disciplines of fusion science and technology. There are various education schemes and work programmes. Organization of summer schools on fusion-related plasma physics is an important part of the training process. Several schools are organized annually or every second year in Europe. Fusion-related science is so vast that it is impossible to cover all topics during an event lasting for one or two weeks. Therefore, each school has its distinctive features and focuses on a selected group of issues to be addressed in depth. This also applies to the Workshop and Summer School on Plasma Physics in Kudowa Zdrój (Poland) that, has been organised annually since 2001. It was initiated by Dr Marek Scholz with the help of his colleagues from the Institute of Plasma Physics and Laser Microfusion (IPPLM) in Warsaw. The idea was to create a forum for students mainly from Eastern Europe to learn and discuss subjects in general plasma physics and dense magnetized media, predominantly in plasma focus devices. Over the years the school has matured and created a clear profile. A unique feature has always been to accommodate in the programme not only tutorials delivered by invited senior scientists but also presentations prepared by the students. In June 2005 the 5th Workshop and Summer School on Plasma Physics was held under the heading 'Towards Fusion Energy: Plasma Physics, Diagnostics, Applications'. There were 59 participants, including 44 students, coming from plasma physics and material research laboratories in 17 countries: Belgium, Czech Republic, France, Germany, Georgia, Iran, Italy, Lithuania, Poland, Romania, Russia

  1. MicroRNA-26a-mediated regulation of interleukin-2 expression in transformed avian lymphocyte lines

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    Smith Lorraine P

    2010-05-01

    Full Text Available Abstract Background Micro(miRNAs are a class of small non-coding RNAs that play critical roles in the induction of various cancers, including lymphomas induced by oncogenic viruses. While some of the miRNAs are oncogenic, miRNAs such as miR-26a are consistently downregulated in a number of cancers, demonstrating their potential tumor suppressor functions. Global miRNA expression profiles of a number of virus-transformed avian lymphoma cell lines have shown downregulation of gga-miR-26a expression, irrespective of molecular mechanisms of transformation or the viral aetiology. The neoplastic transformation of lymphocytes by many viruses accompanies high levels of proliferative responses, mostly mediated through cytokines such as IL-2. Chicken IL-2 can modulate T-cell proliferation and cytotoxicity in vitro and in vivo and dysregulation of IL-2 expression is observed in diseases such as leukaemia. Results The expression levels of gga-miR-26a in chicken lymphoma cells transformed by 3 distinct avian oncogenic viruses, viz Marek's disease virus (MDV, avian leukosis virus (ALV and Reticuloendotheliosis virus (REV were consistently downregulated compared to the levels in the normal lymphocytes. This downregulation of miR-26a regardless of the viral etiology and molecular mechanisms of transformation was consistent with the tumor suppressor role of this miRNA. Notwithstanding this well-established role in cancer, we demonstrate the additional role of this miRNA in directly targeting chicken IL-2 through reporter and biochemical assays. The downregulation of miR-26a can relieve the suppressive effect of this miRNA on IL-2 expression. Conclusions We show that miR-26a is globally downregulated in a number of avian lymphoma cells irrespective of the mechanisms of transformation, reiterating the highly conserved tumor suppressor function of this miRNA. However, with the potential for directly targeting chicken IL-2, the downregulation of miR-26a in these

  2. Pharmacological and toxicological effects of co-exposure of human gingival fibroblasts to silver nanoparticles and sodium fluoride

    Directory of Open Access Journals (Sweden)

    Inkielewicz-Stepniak I

    2014-04-01

    Full Text Available Iwona Inkielewicz-Stepniak,1,* Maria Jose Santos-Martinez,2–4,* Carlos Medina,2,4 Marek W Radomski2,41Department of Medicinal Chemistry, Medical University Gdansk, Debinki, Poland; 2The School of Pharmacy and Pharmaceutical Sciences, Panoz Institute, Trinity College Dublin, Dublin, Ireland; 3School of Medicine, Trinity College Dublin, Dublin, Ireland; 4Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland*These authors contributed equally to this workBackground: Silver nanoparticles (AgNPs and fluoride (F are pharmacological agents widely used in oral medicine and dental practice due to their anti-microbial/anti-cavity properties. However, risks associated with the co-exposure of local cells and tissues to these xenobiotics are not clear. Therefore, we have evaluated the effects of AgNPs and F co-exposure on human gingival fibroblast cells.Methods: Human gingival fibroblast cells (CRL-2014 were exposed to AgNPs and/or F at different concentrations for up to 24 hours. Cellular uptake of AgNPs was examined by transmission electron microscopy. Downstream inflammatory effects and oxidative stress were measured by real-time quantitative polymerase chain reaction (PCR and reactive oxygen species (ROS generation. Cytotoxicity and apoptosis were measured by 3-(4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide (MTT assay and real-time quantitative PCR and flow cytometry, respectively. Finally, the involvement of mitogen-activated protein kinases (MAPK was studied using Western blot.Results: We found that AgNPs penetrated the cell membrane and localized inside the mitochondria. Co-incubation experiments resulted in increased oxidative stress, inflammation, and apoptosis. In addition, we found that co-exposure to both xenobiotics phosphorylated MAPK, particularly p42/44 MAPK.Conclusion: A combined exposure of human fibroblasts to AgNPs and F results in increased cellular damage. Further studies are needed in order to evaluate

  3. An international, multicenter, observational survey to evaluate diabetes control in subjects using insulin for the treatment of type 1 and type 2 diabetes mellitus in the Czech Republic and Slovak Republic: study protocol for a cross-sectional survey

    Directory of Open Access Journals (Sweden)

    Brož J

    2016-06-01

    Full Text Available Jan Brož,1 Denisa Janickova Zdarska,1 Jana Urbanova,2 Marek Brabec,3 Bohumila Krivska,4 Viera Donicova,5 Radka Stepanova,6 Emil Martinka,7 Milan Kvapil1 1Department of Internal Medicine, Second Faculty of Medicine, 2Center for Research on Diabetes, Metabolism and Nutrition, Second Department of Internal Medicine, Third Faculty of Medicine, Charles University, 3Institute of Computer Science of the ASCR, vvi, 4Sanofi, Prague, Czech Republic; 5Private Department of Diabetology, Internal Medicine and Metabolism, Kosice, Slovak Republic; 6ADDS sro, Brno, Czech Republic; 7National Institute of Endocrinology and Diabetology, Lubochna, Slovak Republic Background: Despite the improvements in insulin therapy, a large number of patients fail to achieve their target glycated hemoglobin (HbA1c levels. Control of diabetes is often unsatisfactory because the patient does not know about the principles of successful insulin therapy (ie, blood glucose self-monitoring, the principles of insulin administration, titration, current dose adjustments, dietary recommendations, and physical activity preventive measures or because these principles are applied incorrectly or insufficiently. Furthermore, the fear of hypoglycemia may lead to maintaining higher than recommended blood glucose levels. Methods/design: This is a noninterventional, international study focusing on a questionnaire survey of diabetes patients (patient-reported outcome treated with insulin for at least 1 year. It is designed so that the data obtained reflect real access of patients to insulin treatment. The primary objective is to show the results of glycemic control of diabetes (HbA1c achieved in diabetes patients treated with at least one dose of insulin. The secondary objective is to monitor the factors potentially affecting these results, which include the frequency and other characteristics of hypoglycemia, the frequency of blood glucose self-monitoring, and the effects produced when the results

  4. Oscillatory dynamics in a model of vascular tumour growth - implications for chemotherapy

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    Maini PK

    2010-04-01

    differential equations (PDEs. Employing a combination of numerical and analytical techniques, we demonstrate how the spatio-temporal dynamics of the untreated tumour may influence its response to chemotherapy. Reviewers This manuscript was reviewed by Professor Zvia Agur and Professor Marek Kimmel.

  5. Pharmacokinetics, safety, and efficacy of APF530 (extended-release granisetron in patients receiving moderately or highly emetogenic chemotherapy: results of two Phase II trials

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    Gabrail N

    2015-03-01

    Full Text Available Nashat Gabrail,1 Ronald Yanagihara,2 Marek Spaczyński,3 William Cooper,4 Erin O'Boyle,5 Carrie Smith,1 Ralph Boccia6 1Gabrail Cancer Center, Canton, OH, USA; 2St Louise Regional Hospital, Gilroy, CA, USA; 3Department of Gynecology, Obstetrics and Gynecologic Oncology, University of Medical Sciences, Poznan, Poland; 4TFS International, Flemington, NJ, USA; 5FibroGen, Inc., San Francisco, CA, USA; 6Center for Cancer and Blood Disorders, Bethesda, MD, USA Background: Despite advances with new therapies, a significant proportion of patients (>30% suffer delayed-onset chemotherapy-induced nausea and vomiting (CINV despite use of antiemetics. APF530 is a sustained-release subcutaneous (SC formulation of granisetron for preventing CINV. APF530 pharmacokinetics, safety, and efficacy were studied in two open-label, single-dose Phase II trials (C2005-01 and C2007-01, respectively in patients receiving moderately emetogenic chemotherapy or highly emetogenic chemotherapy. Methods: In C2005-01, 45 patients received APF530 250, 500, or 750 mg SC (granisetron 5, 10, or 15 mg, respectively. In C2007-01, 35 patients were randomized to APF530 250 or 500 mg SC. Injections were given 30 to 60 minutes before single-day moderately emetogenic chemotherapy or highly emetogenic chemotherapy. Plasma granisetron was measured from predose to 168 hours after study drug administration. Safety and efficacy were also evaluated. Results: APF530 pharmacokinetics were dose proportional, with slow absorption and elimination of granisetron after a single SC dose. Median time to maximum plasma concentration and half-life were similar for APF530 250 and 500 mg in both trials, with no differences between the groups receiving moderately and highly emetogenic chemotherapy. Exposure to granisetron was maintained at a therapeutic level over the delayed-onset phase, at least 168 hours. Adverse events in both trials were as expected for granisetron; injection site reactions (eg, erythema

  6. Some Metric Properties of Planar Gaussian Free Field

    Science.gov (United States)

    Goswami, Subhajit

    behavior by showing that the expected exit time from a ball of radius N scales as Npsi(gamma)+o(1) with psi(gamma) > 2 for all gamma > 0. The contents of these chapters are based on a joint work with Marek Biskup and Jian Ding.

  7. Titanium dioxide nanoparticles enhance production of superoxide anion and alter the antioxidant system in human osteoblast cells

    Directory of Open Access Journals (Sweden)

    Niska K

    2015-02-01

    Full Text Available Karolina Niska,1 Katarzyna Pyszka,1 Cecylia Tukaj,2 Michal Wozniak,1 Marek Witold Radomski,3–5 Iwona Inkielewicz-Stepniak1 1Department of Medical Chemistry, 2Department of Electron Microscopy, Medical University of Gdansk, Gdansk, Poland; 3School of Pharmacy and Pharmaceutical Sciences, Trinity Biomedical Sciences Institute, The University of Dublin Trinity College, Dublin, Ireland; 4Kardio-Med Silesia, 5Silesian Medical University, Zabrze, Poland Abstract: Titanium dioxide (TiO2 nanoparticles (NPs are manufactured worldwide for a variety of engineering and bioengineering applications. TiO2NPs are frequently used as a material for orthopedic implants. However, to the best of our knowledge, the biocompatibility of TiO2NPs and their effects on osteoblast cells, which are responsible for the growth and remodeling of the human skeleton, have not been thoroughly investigated. In the research reported here, we studied the effects of exposing hFOB 1.19 human osteoblast cells to TiO2NPs (5–15 nm for 24 and 48 hours. Cell viability, alkaline phosphatase (ALP activity, cellular uptake of NPs, cell morphology, superoxide anion (O2•- generation, superoxide dismutase (SOD activity and protein level, sirtuin 3 (SIR3 protein level, correlation between manganese (Mn SOD and SIR, total antioxidant capacity, and malondialdehyde were measured following exposure of hFOB 1.19 cells to TiO2NPs. Exposure of hFOB 1.19 cells to TiO2NPs resulted in: (1 cellular uptake of NPs; (2 increased cytotoxicity and cell death in a time- and concentration-dependent manner; (3 ultrastructure changes; (4 decreased SOD and ALP activity; (5 decreased protein levels of SOD1, SOD2, and SIR3; (6 decreased total antioxidant capacity; (7 increased O2•- generation; and (8 enhanced lipid peroxidation (malondialdehyde level. The linear relationship between the protein level of MnSOD and SIR3 and between O2•- content and SIR3 protein level was observed. Importantly, the cytotoxic

  8. The effects of exercise training and caloric restriction on the cardiac oxytocin natriuretic peptide system in the diabetic mouse

    Directory of Open Access Journals (Sweden)

    Broderick TL

    2017-01-01

    Full Text Available Tom L Broderick,1 Marek Jankowski,2 Jolanta Gutkowska2 1Department of Physiology, Laboratory of Diabetes and Exercise Metabolism, Midwestern University, Glendale, AZ, USA; 2Department of Medicine, Laboratory of Cardiovascular Biochemistry, Centre Hospitalier de l‘Université de Montréal-Hôtel-Dieu, Montréal, QC, Canada Background: Regular exercise training (ET and caloric restriction (CR are the frontline strategies in the treatment of type 2 diabetes mellitus with the aim at reducing cardiometabolic risk. ET and CR improve body weight and glycemic control, and experimental studies indicate that these paradigms afford cardioprotection. In this study, the effects of combined ET and CR on the cardioprotective oxytocin (OT–natriuretic peptide (NP system were determined in the db/db mouse, a model of type 2 diabetes associated with insulin resistance, hyperglycemia, and obesity. Methods: Five-week-old male db/db mice were assigned to the following groups: sedentary, ET, and ET + CR. Nonobese heterozygote littermates served as controls. ET was performed on a treadmill at moderate intensity, and CR was induced by reducing food intake by 30% of that consumed by sedentary db/db mice for a period of 8 weeks. Results: After 8 weeks, only ET + CR, but not ET, slightly improved body weight compared to sedentary db/db mice. Regardless of the treatment, db/db mice remained hyperglycemic. Hearts from db/db mice demonstrated reduced expression of genes linked to the cardiac OT–NP system. In fact, compared to control mice, mRNA expression of GATA binding protein 4 (GATA4, OT receptor, OT, brain NP, NP receptor type C, and endothelial nitric oxide synthase (eNOS was decreased in hearts from sedentary db/db mice. Both ET alone and ET + CR increased the mRNA expression of GATA4 compared to sedentary db/db mice. Only ET combined with CR produced increased eNOS mRNA and protein expression. Conclusion: Our data indicate that enhancement of eNOS by combined

  9. The Earth System Course at the University of Oklahoma: Science and Pedagogy Aimed at Pre-service Teachers

    Science.gov (United States)

    Postawko, S.; Soreghan, M.; Marek, E.

    2005-12-01

    Traditionally, education majors at the University of Oklahoma took either Introduction to Physical Geology or Introduction to Meteorology to fulfill their physical sciences requirement. Science education majors were required to take both courses. These courses are large-enrollment lecture type courses, with required lab sections taught by graduate teaching assistants. Beginning in 1997, faculty from the Colleges of Education and Geosciences at the University of Oklahoma began working together to provide effective earth science education for pre-service teachers. The first step in this collaboration was the development of a new course on The Earth System that focuses on Earth as a whole rather than on the more narrow focus of either the geology or meteorology courses. The new course, which was taught for the first time in the Spring of 2001, covers a number of major themes related to Earth Science, including the Carbon Cycle, Earth Materials, Plate Tectonics, Atmosphere and Oceans. The particular concepts within each theme were chosen based on two criteria: 1) alignment with content advocated by national (NSES) and state (Priority Academic Student Skills-PASS) standards; and 2) they are amenable to a learning cycle pedagogical approach. Besides an interdisciplinary approach to the content, the new course features pedagogical innovations. In lieu of independent laboratory and lecture times, we scheduled two class periods of longer duration, so that active learning, involving hands-on activities and experiments were possible throughout each class period. The activities modeled the learning-cycle approach with an exploration, concept invention, and an expansion phase (Marek and Cavallo, 1997). Therefore, the pre-service teachers experienced the learning cycle in practice prior to learning the theory in their upper division "methods" course. In the first 3 years that the course was taught, students were given surveys early in the semester and at the end of the semester

  10. Antimicrobial nanocapsules: from new solvent-free process to in vitro efficiency

    Directory of Open Access Journals (Sweden)

    Steelandt J

    2014-09-01

    Full Text Available Julie Steelandt,1 Damien Salmon,1,2 Elodie Gilbert,1 Eyad Almouazen,3 François NR Renaud,4 Laurène Roussel,1 Marek Haftek,5 Fabrice Pirot1,2 1University Claude Bernard Lyon 1, Faculty of Pharmacy, Fundamental, Clinical and Therapeutic Aspects of Skin Barrier Function, FRIPharm, Laboratoire de Pharmacie Galénique Industrielle, 2Hospital Pharmacy, FRIPharm, Hospital Edouard Herriot, Hospices Civils de Lyon, 3Laboratoire d’Automatique et de Génie des Procédés, University Claude Bernard Lyon 1, 4University Claude Bernard Lyon 1, UMR CNRS 5510/MATEIS, 5University Claude Bernard Lyon 1, Faculty of Pharmacy, Fundamental, Clinical and Therapeutic Aspects of Skin Barrier Function, FRIPharm, Laboratoire de Dermatologie, Lyon, France Abstract: Skin and mucosal infections constitute recurrent pathologies resulting from either inappropriate antiseptic procedures or a lack of efficacy of antimicrobial products. In this field, nanomaterials offer interesting antimicrobial properties (eg, long-lasting activity; intracellular and tissular penetration as compared to conventional products. The aim of this work was to produce, by a new solvent-free process, a stable and easily freeze-dryable chlorhexidine-loaded polymeric nanocapsule (CHX-NC suspension, and then to assess the antimicrobial properties of nanomaterials. The relevance of the process and the physicochemical properties of the CHX-NCs were examined by the assessment of encapsulation efficiency, stability of the nanomaterial suspension after 1 month of storage, and by analysis of granulometry and surface electric charge of nanocapsules. In vitro antimicrobial activities of the CHX-NCs and chlorhexidine digluconate solution were compared by measuring the inhibition diameters of two bacterial strains (Escherichia coli and Staphylococcus aureus and one fungal strain (Candida albicans cultured onto appropriate media. Based on the findings of this study, we report a new solvent-free process for the

  11. Optimal management of idiopathic scoliosis in adolescence

    Directory of Open Access Journals (Sweden)

    Kotwicki T

    2013-07-01

    Full Text Available Tomasz Kotwicki,1 Joanna Chowanska,1,2 Edyta Kinel,3 Dariusz Czaprowski,4,5 Marek Tomaszewski,1 Piotr Janusz1 1Department of Pediatric Orthopedics, University of Medical Sciences, Poznan, Poland; 2National Scoliosis Foundation, Stoughton, MA, USA; 3Department of Rehabilitation, University of Medical Sciences, Poznan Poland; 4Department of Physiotherapy, Józef Rusiecki University College, Olsztyn, 5Rehasport Clinic, Poznan, Poland Abstract: Idiopathic scoliosis is a three-dimensional deformity of the growing spine, affecting 2%–3% of adolescents. Although benign in the majority of patients, the natural course of the disease may result in significant disturbance of body morphology, reduced thoracic volume, impaired respiration, increased rates of back pain, and serious esthetic concerns. Risk of deterioration is highest during the pubertal growth spurt and increases the risk of pathologic spinal curvature, increasing angular value, trunk imbalance, and thoracic deformity. Early clinical detection of scoliosis relies on careful examination of trunk shape and is subject to screening programs in some regions. Treatment options are physiotherapy, corrective bracing, or surgery for mild, moderate, or severe scoliosis, respectively, with both the actual degree of deformity and prognosis being taken into account. Physiotherapy used in mild idiopathic scoliosis comprises general training of the trunk musculature and physical capacity, while specific physiotherapeutic techniques aim to address the spinal curvature itself, attempting to achieve self-correction with active trunk movements developed in a three-dimensional space by an instructed adolescent under visual and proprioceptive control. Moderate but progressive idiopathic scoliosis in skeletally immature adolescents can be successfully halted using a corrective brace which has to be worn full time for several months or until skeletal maturity, and is able to prevent more severe deformity and avoid

  12. Raw Pea (Pisum sativum, raw Faba bean (Vicia faba var. minor and raw Lupin (Lupinus albus var. multitalia as alternative protein sources in broiler diets

    Directory of Open Access Journals (Sweden)

    Gianfranco Piva

    2010-01-01

    Full Text Available The ban of the meat and bone meal for entering animal diets and the concern of transgenic feeds poses a challenge toanimal nutritionists in Europe. The challenge is to find homegrown protein-rich feedstuffs, making sure no antinutritionalfactors are present which could interfere in the animals’ performance. The raw Pea (Pisum sativum (RP, raw Fababean (Vicia faba, variety minor (RFb and raw Lupin (Lupinus albus, variety multitalia (RL were evaluated as alternativeprotein sources into broiler diets. Six hundred thirty 1d-old Ross male chicks, Marek vaccinated, were randomlyassigned to seven dietary treatments (5 pens per treatment/18 birds per pen. Chicks were floor housed, ad libitum fedisocaloric and isonitrogenous diets and had free access to water. Artificial light was provided 10 h/d. The bulk of the basediet (control diet was corn (48.7%, 56.6% and 57%, solvent-extracted soybean meal (42.8%, 37.3% and 33.4%, cornoil (4.4%, 5.2% and 6.3%, plus synthetic amino acids, minerals, trace minerals and vitamins, respectively for the 1-10d-old, 11-28d-old and 29 to 42d-old growing periods. The RP, RFb and RL entered diets in substitution of the soybeanand corn according to the cost optimization (P100, Fb100 and L100, respectively for RP, RFb and RL and at half of theoptimized quantity (RP50, RFb50 and RL50, respectively for RP, RFb and RL. The amount used as fed basis for the higherlevel of inclusion were: P100: 350 g/kg for all diets; Fb100: 480 g/kg (1-10d-old and 500 g/kg (11-42d-old; L100:360 g/kg (1-10d-old and 300 g/kg (11-42d-old. The average daily gain (ADG were lower (P compared to the control group. Over the whole period of growth, the RFb group had similar ADG compared to the controlgroup and for both levels of inclusion, whereas reduced (P (P growth. Birds performance was improved (P and breast and leg quarter cuts. The RFb and RL could represent valuable protein feeds in broilers diet formulation.

  13. Epidemiology of "fragile skin": results from a survey of different skin types

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    Haftek M

    2013-12-01

    Full Text Available Marek Haftek,1 Christine Coutanceau,2 Charles Taïeb3 1Université Lyon 1, Laboratoire de Recherche Dermatologique, Faculté de Médecine et de Pharmacie, Lyon, 2Département Médical, Laboratoires Dermatologiques A-Derma, Lavaur, 3Public Health, Pierre Fabre SA, Paris, France Background: Epidemiologic information regarding the prevalence of "fragile skin" in different adult populations is currently limited. The objective of the current survey was to assess the occurrence of perceived "fragile skin" across different skin types in the general adult population. Methods: Individuals aged 15–65 years from five representative geographic regions (France, Spain, Sweden, Japan, and the US were interviewed and grouped into the following skin types: Caucasian North skin (n=1,218, Caucasian South skin (n=1,695, Asian skin (n=1,500, and Black skin (n=500. The main survey question was "In your opinion, do you have fragile skin?" Concepts relating to the nature and appearance of an individual's skin were also evaluated. Results: A total of 4,913 individuals were interviewed. Subjects in the Caucasian North, Caucasian South, Asian, and Black skin type groups responded positively to the question "In your opinion, do you have fragile skin?" in the following proportions: 24.44%, 29.71%, 52.67%, and 42.20%, respectively. With the exception of individuals in the Black skin group, "fragile skin" was prevalent in significantly more women than men (P<0.0001. Compared with other age categories, the prevalence of "fragile skin" was significantly higher in individuals aged 15–34 years (P<0.0001, regardless of skin type. In general, individuals reporting "fragile skin" were 2–3-fold more likely to respond positively to a series of questions relating to the nature and appearance of their skin. The prevalence of "fragile skin" was also higher in individuals who experienced dermatosis (skin lesions of any type in the previous 12 months. Conclusion: Whilst these

  14. Comparative virology and AIDS (review).

    Science.gov (United States)

    Kodama, M; Kodama, T

    1996-03-01

    The scientific debate between pros and cons of the HIV criminal theory of AIDS still remains unsettled. The purpose of this review is to promote resolution of the problem by extracting a common principle of the host-virus relation using data resources for each of 4 viruses as follows: a) polyoma virus, b) Marek's disease virus, c) Ebola virus, d) Korean hemorrhagic fever virus. Conclusions drawn from this study are given as follows: i) Environment emerged as the cardinal factor to modify the process of virus infection in all of the 4 viruses studied. Above all, an accelerating effect of environmental stress on the progression of virus infection was noted in vivo in the majority of viral diseases. ii) Evidence is available to indicate that a healthy cell (or a healthy individual) may harbor virus genes of multiple species without manifesting any pathologic sign. iii) Evidence also suggests that the biological property as well as morphological structure of a virus may vary in reponse to a change of the bioenvironment. On the basis of the above information, we propose to renounce 2 assumptions of classical infection model: a) the hereditarily determined virulence of a microorganism (including virus) be the sole determinant of infection to the effect that its invasion into the host should automatically complete the programmed course of infection; b) virus, a quasi-living creature, should reserve its behavioral independence irrespective of a change of the bioenvironment. The new infection model was constructed on the basis of the selfish gene concept that had been invented by Richard Dawkins to explain the altruistic behavior of an individual. That is, the fate of an exogenous or endogenous virus is under the dual control of the host genome (selfish gene) and the outer environment. The progression of virus infection is conditioned by a crosstalk between them. The selfish gene may use virus (a lifeless substance) as a magic bullet to induce a designated host response. In

  15. Effects of immunosuppressive treatment on protein expression in rat kidney

    Directory of Open Access Journals (Sweden)

    Kędzierska K

    2014-09-01

    Full Text Available Karolina Kędzierska,1 Katarzyna Sporniak-Tutak,2 Krzysztof Sindrewicz,2 Joanna Bober,3 Leszek Domański,1 Mirosław Parafiniuk,4 Elżbieta Urasińska,5 Andrzej Ciechanowicz,6 Maciej Domański,1 Tomasz Smektała,2 Marek Masiuk,5 Wiesław Skrzypczak,6 Małgorzata Ożgo,6 Joanna Kabat-Koperska,1 Kazimierz Ciechanowski1 1Department of Nephrology, Transplantology, and Internal Medicine, 2Department of Dental Surgery, 3Department of Medical Chemistry, 4Department of Forensic Medicine, 5Department of Pathomorphology, Pomeranian Medical University, 6Department of Physiology, Cytobiology, and Proteomics, West Pomeranian University of Technology, Szczecin, Poland Abstract: The structural proteins of renal tubular epithelial cells may become a target for the toxic metabolites of immunosuppressants. These metabolites can modify the properties of the proteins, thereby affecting cell function, which is a possible explanation for the mechanism of immunosuppressive agents' toxicity. In our study, we evaluated the effect of two immunosuppressive strategies on protein expression in the kidneys of Wistar rats. Fragments of the rat kidneys were homogenized after cooling in liquid nitrogen and then dissolved in lysis buffer. The protein concentration in the samples was determined using a protein assay kit, and the proteins were separated by two-dimensional electrophoresis. The obtained gels were then stained with Coomassie Brilliant Blue, and their images were analyzed to evaluate differences in protein expression. Identification of selected proteins was then performed using mass spectrometry. We found that the immunosuppressive drugs used in popular regimens induce a series of changes in protein expression in target organs. The expression of proteins involved in drug, glucose, amino acid, and lipid metabolism was pronounced. However, to a lesser extent, we also observed changes in nuclear, structural, and transport proteins' synthesis. Very slight differences

  16. Herpesvirus telomerase RNA (vTR with a mutated template sequence abrogates herpesvirus-induced lymphomagenesis.

    Directory of Open Access Journals (Sweden)

    Benedikt B Kaufer

    2011-10-01

    Full Text Available Telomerase reverse transcriptase (TERT and telomerase RNA (TR represent the enzymatically active components of telomerase. In the complex, TR provides the template for the addition of telomeric repeats to telomeres, a protective structure at the end of linear chromosomes. Human TR with a mutation in the template region has been previously shown to inhibit proliferation of cancer cells in vitro. In this report, we examined the effects of a mutation in the template of a virus encoded TR (vTR on herpesvirus-induced tumorigenesis in vivo. For this purpose, we used the oncogenic avian herpesvirus Marek's disease virus (MDV as a natural virus-host model for lymphomagenesis. We generated recombinant MDV in which the vTR template sequence was mutated from AATCCCAATC to ATATATATAT (vAU5 by two-step Red-mediated mutagenesis. Recombinant viruses harboring the template mutation replicated with kinetics comparable to parental and revertant viruses in vitro. However, mutation of the vTR template sequence completely abrogated virus-induced tumor formation in vivo, although the virus was able to undergo low-level lytic replication. To confirm that the absence of tumors was dependent on the presence of mutant vTR in the telomerase complex, a second mutation was introduced in vAU5 that targeted the P6.1 stem loop, a conserved region essential for vTR-TERT interaction. Absence of vTR-AU5 from the telomerase complex restored virus-induced lymphoma formation. To test if the attenuated vAU5 could be used as an effective vaccine against MDV, we performed vaccination-challenge studies and determined that vaccination with vAU5 completely protected chickens from lethal challenge with highly virulent MDV. Taken together, our results demonstrate 1 that mutation of the vTR template sequence can completely abrogate virus-induced tumorigenesis, likely by the inhibition of cancer cell proliferation, and 2 that this strategy could be used to generate novel vaccine candidates

  17. Ground source geothermal heat. Ground source heat pumps and underground thermal energy storage systems. Proceedings; Oberflaechennahe Geothermie. Erdgekoppelte Waermepumpen und unterirdische thermische Energiespeicher. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    At the ninth international user forum on shallow geothermal heat on 28th and 29th April, 2009, at BadStaffelstein (Federal Republic of Germany), the following lectures were held: (1) Information system on shallow geothermal heat for Bavaria (Marcellus Schulze); (2) Calculation of the spreading of temperature anomalies in groundwater as an instrument of planning of heat pump systems (Wolfgang Rauch); (3) Comparison of models for simulation of deep geothermal probes (Markus Proell); (4) Impact of the geometry of boreholes and probes on heat transport (Manfred Reuss); (5) Thermal respond tests and temperature depth profiles - Experience from research and practice (Markus Kuebert); (6) A model of simulation for the investigation of the impact of different heat transfer fluids on the efficiency of ground source heat pump devices (Roland Koenigsdorff); (7) The research project EWSplus - Investigations for quality assurance of geothermal probes (Mathieu Riegger); (8) Quality management of plants for the utilization of shallow geothermal heat with geothermal probes - the example of Baden-Wuerttemberg (Bruno Lorinser, Ingrid Stober); (9) Not every heat pump contributes to climate protection (Falk Auer); (10) Field measurements of heat pumps in residential buildings with modern standard and in older buildings (Marek Miara); (11) System technology for a great annual performance factor (Werner Schenk); (12) Modification of older geothermal heat probe devices for use with modern heat pumps (Klaus Friedrich Staerk); (13) Energy-efficient modernisation of a pensioners' condominium from the 1970s with solar-geothermal-air (Michael Guigas); (14) Evaluation and optimization of operation of seasonal storage systems in the foundations of office buildings (Herdis Kipry); (15) Evaluation of an innovative heating and cooling concept with rain water vessels, thermo-active building components and phase change materials in a residential building (Doreen Kalz); (16) Contracts for ground

  18. PLASMA-2005: International Conference on Research and Applications of Plasmas combined with the 3. German-Polish Conference on Plasma Diagnostics for Fusion and Applications and the 5. French-Polish Seminar on Thermal Plasma in Space and Laboratory. Book of Abstracts

    International Nuclear Information System (INIS)

    Ksiazek, K.

    2005-01-01

    The International Conferences 'PLASMA' have been organized in Poland every two years since 1993. The German-Polish Conferences on Plasma Diagnostics were started in 2002, and the French-Polish Seminars on Thermal Plasmas were initiated in 1997. To reduce a number of topical conferences and to improve an exchange of information among different plasma research groups it was agreed to organize for the first time the triple conference at the Opole University, Poland, on September 6-9, 2005. The chairman of the International Scientific Committee (ISC) was Professor Marek J. Sadowski from IPJ in Swierk, and the co-chairmen were Professor Thomas Klinger of the IPP-Greifswald and Professor Michel Dudeck of the CNRS-Orleans. The chairman of LOC was Professor Jozef Musielok of the Opole University. This conference was designed for interested scientists, engineers and students from all the countries, but particularly for these from the Central and Eastern Europe (see http://draco.uni.opole.pl/plasma2005). The scientific programme of the conference embraced almost all directions of plasma research and technology, i.e.: 1. Elementary processes and general theory of plasma; 2. Plasmas in tokamaks, stellerators and related experiments; 3. plasmas in Z-pinch and PF discharges; 4. Plasmas produced by intense laser beams; 5. Plasmas of micro-wave and glow discharges; 6. Plasmas in spark- and arc-discharges; 7. Plasmas in space; 8. Diagnostics and experimental facilities; 9. Applications of quasi-stationary and pulsed plasmas. Participants of the conference were 127 plasma experts (including 23 invited speakers) from 13 different countries, as well as several honorary guests from local authorities and the most important plasma research centers in Poland. Most numerous groups came from Poland (58 persons), Germany (15 persons), France (14 persons), Czech Republic (11 persons), Russia (7 persons), and Ukraine (6 persons). The participants came also from Belarus, Hungary, Iran, Japan

  19. COMT Val158Met, but not BDNF Val66Met, is associated with white matter abnormalities of the temporal lobe in patients with first-episode, treatment-naïve major depressive disorder: a diffusion tensor imaging study

    Directory of Open Access Journals (Sweden)

    Hayashi K

    2014-06-01

    Full Text Available Kenji Hayashi,1 Reiji Yoshimura,1 Shingo Kakeda,2 Taro Kishi,3 Osamu Abe,4 Wakako Umene-Nakano,1 Asuka Katsuki,1 Hikaru Hori,1 Atsuko Ikenouchi-Sugita,1 Keita Watanabe,2 Satoru Ide,2 Issei Ueda,2 Junji Moriya,2 Nakao Iwata,3 Yukunori Korogi,2 Marek Kubicki,5 Jun Nakamura1 1Department of Psychiatry, 2Department of Radiology, University of Occupational and Environmental Health, Kitakyushu, Japan; 3Department of Psychiatry, Fujita Health University, Toyoake, Japan; 4Department of Radiology, Nihon University School of Medicine, Tokyo, Japan; 5Psychiatry Neuroimaging Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA Abstract: We investigated the association between the Val158Met polymorphism of the catechol-O-methyltransferase (COMT gene, the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF gene, and white matter changes in patients with major depressive disorder (MDD and healthy subjects using diffusion tensor imaging (DTI. We studied 30 patients with MDD (17 males and 13 females, with mean age ± standard deviation [SD] =44±12 years and 30 sex- and age-matched healthy controls (17 males and 13 females, aged 44±13 years. Using DTI analysis with a tract-based spatial statistics (TBSS approach, we investigated the differences in fractional anisotropy, radial diffusivity, and axial diffusivity distribution among the three groups (patients with the COMT gene Val158Met, those with the BDNF gene Val66Met, and the healthy subjects. In a voxel-wise-based group comparison, we found significant decreases in fractional anisotropy and axial diffusivity within the temporal lobe white matter in the Met-carriers with MDD compared with the controls (P<0.05. No correlations in fractional anisotropy, axial diffusivity, or radial diffusivity were observed between the MDD patients and the controls, either among those with the BDNF Val/Val genotype or among the BDNF Met-carriers. These results suggest an association

  20. Samoocena, a wybrane elementy pozycji społecznej judoków = Self-assessment and selected elements of the social position of judokas

    Directory of Open Access Journals (Sweden)

    Patrycja Janowska

    2016-09-01

    Janowska Patrycja1, Wojdat Marta1, Antkowiak Magdalena1, Stępniak Robert2, Adam Marek3   1Studenckie Koło Naukowe "WyKoNa", Uniwersytet Kazimierza Wielkiego, Bydgoszcz, Polska 2Instytut Kultury Fizycznej, Uniwersytet Kazimierza Wielkiego, Bydgoszcz, Polska 3Zakład Sportów Walki, Akademia Wychowania Fizycznego i Sportu, Gdańsk, Polska   Corresponding author: Stępniak Robert Ph. D Instytut Kultury Fizycznej, Uniwersytet Kazimierza Wielkiego, ul. Sportowa 2, 85-091 Bydgoszcz Polska email:     Słowa kluczowe: samoocena, pozycja społeczna, zawodnicy judo Keywords: self-esteem social position, judo fighters     Samoocena, a wybrane elementy pozycji społecznej judoków Self-assessment and selected elements of the social position of judokas   Streszczenie   Cel: Określenie liczbowe poziomu samooceny populacji judoków, oraz znalezienie ewentualnych związków z czynnikami określającymi pozycje społeczną. Materiał i metody: Przebadano 53 osobowa grupę judoków i byłych -nadal trenujących judoków używając ankiety samooceny Rosenberga SES, w polskiej adaptacji. Wyniki: Podgrupa społeczna judoków wykazuje się wysoką samooceną, wysokim wykształceniem i ponadprzeciętnym wynagrodzeniem za prace zarobkową. Wnioski: Istnieją istotne związki pomiędzy wynikami samooceny SES, a czynnikami określającymi daną osobę w społeczeństwie.         Abstract   Aim: To determine the numerical level of self-esteem of the judokas population and to find possible links with the factors determining the social position. Material and Methods: 53 current and formerly judokas - still trained. Research conducted using the self-assessment surveys Rosenberg SES in Polish adaptation. Results: Subgroup social judokas showed high self-esteem, high education and above-average remuneration paid for the work. Conclusions: There are significant relationships between the results of self-assessment - SES, and the factors defining a person in society.

  1. School students "Catch a Star"!

    Science.gov (United States)

    2007-04-01

    School students from across Europe and beyond have won prizes in an astronomy competition, including the trip of a lifetime to one of the world's most powerful astronomical observatories, on a mountaintop in Chile. ESO, the European Organisation for Astronomical Research in the Southern Hemisphere, together with the European Association for Astronomy Education (EAAE), has just announced the winners of the 2007 "Catch a Star!" competition. ESO PR Photo 21/07 "Catch a Star!" is an international astronomy competition for school students, in which students are invited to 'become astronomers' and explore the Universe. The competition includes two categories for written projects on astronomical themes, to ensure that every student, whatever their level, has the chance to enter and win exciting prizes. For the artistically minded, "Catch a Star!" also includes an astronomy-themed artwork competition. Students from 22 countries submitted hundreds of written projects and pieces of artwork. "The standard of entries was most impressive, and made the jury's task of choosing winners both enjoyable and difficult! We hope that everyone, whether or not they won a prize, had fun taking part, and learnt some exciting things about our Universe", said Douglas Pierce-Price, Education Officer at ESO. The top prize, of a week-long trip to Chile to visit the ESO Very Large Telescope (VLT) on Paranal, was won by students Jan Mestan and Jan Kotek from Gymnazium Pisek in the Czech Republic, together with their teacher Marek Tyle. Their report on "Research and Observation of the Solar Eclipse" told how they had studied solar eclipses, and involved their fellow students in observations of an eclipse from their school in 2006. The team will travel to Chile and visit the ESO VLT - one of the world's most powerful optical/infrared telescopes - where they will meet astronomers and be present during a night of observations on the 2600m high Paranal mountaintop. "It's fantastic that we will see the

  2. Paphlagonia Bölgesi’nde Geç Antik ve Erken Bizans Yerleşimi: Sora / Late Antique and Early Byzantine Settlement in Paphlagonia Region: Sora

    Directory of Open Access Journals (Sweden)

    Durmuş Gür

    2017-06-01

    Full Text Available Abstract The late antique, early Byzantine settlement area locates at 12 km. distance to southwest of Karabuk Central District, on a sloping land with an altitude of 700 meters piedmont of Keltepe mountain. This settlement area, called as Zora, Zara, Zopran, Sora, Sopran or some other similar names by the researchers, locates within the boundaries of Akören (Kaleköy and Zopran today. This area is one of the five central eparchies bounded to Paphlagonia district of Gangra (Çankırı. Various column headers, inscriptions, sculptures, Hellenistic sepulchres and architectural ruins belonging to Roman age are identified there. The settlement area called as Sora since the 4th century is observed by Doublet (1889, Mendel (1901, Gökoğlu (1952, Marek (1993, 2003, Belke (1996 and Umar (2007, and they found out that it used to be called Zobran in the records of 16th century Ottoman archive. Within the scope of this research, Sora is observed in details for the periods of Roman, Byzantine and Ottoman. The life of St. Autonomous, who had came there in the 4th century to proselytize Christianity and became a martyre, their sepulchre constructions, the bishops of the city, architectural plastic works and scriptures are all researched. Moreover, the problem of naming the area which was confusing for many years is tried to be solved by this research beside documenting the present condition of the architectural ruin on their original places. Öz Karabük’ün 12 km. güneybatısında bulunan geç Antik-erken Bizans dönemi yerleşim alanı Sora (günümüzde Zopran ve Akören, Keltepe Dağı’nın eteklerinde ortalama 700 m. rakımda eğimli bir arazi üzerinde yer almaktadır. Araştırmacılar tarafından Zora, Zara, Zopran, Sora, Sopran gibi çeşitli isimlerle adlandırılan yerleşim, günümüzde Akören (Kaleköy ve Zopran sınırlarında kalmaktadır. Sora, Paphlagonia bölgesinde Gangra (Çankırı Metropolitliğine bağlı beş Piskoposluk

  3. Vladimir Prelog i Zavod za organsku kemiju

    Directory of Open Access Journals (Sweden)

    Jakopčić, K.

    2007-03-01

    Full Text Available The Department of organic chemistry was founded on October 1st, 1922 as part of the Chemical Engineering Department of the High Technical School in Zagreb. The first-appointed professor of organic chemistry was Ivan Marek, formerly the professor at the School of Trade in Zagreb. The High Technical School with all its departments was soon (1926/27 incorporated into the University of Zagreb and became the nucleus of the Technical Faculty. The management of the faculty was fully aware of the necessity to engage the best scientists in the field as faculty professors. As far as organic chemistry was concerned, there was no better choice in the mid 1930's, than to invite young but already recognized organic chemist Dr. Vladimir Prelog to join the staff and to succeed professor Marek, who retired in 1935. Dr. Prelog did not hesitate to accept the invitation and was eager to continue his scientific work in an academic laboratory in Zagreb. At the time of the invitation, Dr. Prelog was engaged in a small laboratory synthesizing special samples of rare chemicals to be sold through the chemical store "Dřiza" in Prague. There he was provided the modest opportunity to carry on his own research, and together with Rudolf Lukeš and Emil Votoček, published a number of papers concerning organic synthesis and chemistry of natural products. Elected in Zagreb for the lectureship of the assistant professor in organic chemistry, Prelog started teaching as early as in the summer semester of 1934/35. The ingenious and bright lecturing of young professor Prelog inspired his students, and many of them were attracted to organic chemistry. On the other hand, the working conditions in the disposable laboratory of the Organic Chemistry Department were too modest to accept a number of students. The budget was so small that it only covered tuition, while there was no research fund at the faculty. Luckily, Dr. Prelog did not hesitate to accept an offer for scientific co

  4. UU* filtering of nighttime net ecosystem CO2 exchange flux over forest canopy under strong wind in wintertime

    Institute of Scientific and Technical Information of China (English)

    ZHANG; Junhui

    2005-01-01

    effects and density fluxes, Boundary-Layer Meteorology, 2000, 97:487-511.[12]Massman, W. J., Sommerfeld, R. A., Mosier, A. R. et al., A model investigation of turbulence-driven pressure-pumping effects on the rate of diffusion of CO2, N2O and CH4 through Layered snowpacks, Journal of Geophysical Research (D), 1997, 102:18851-18863.[13]Bink, N. J., The structure of the atmospheric surface layer subject to local advection, Ph. D. Thesis, Agricultural University, Wageningen, The Netherlands, 1996.[14]Raupach, M. R., Weng, W. S., Carruthers, D. J. et al., Temperature and humidity fields and fluxes over hills, Quart. J. Roy Meteoroi. Soc., 1992, 118: 191-225.[15]Aubinet, M., Heinesch, B., Yernaux, M., Horizontal and vertical CO2 advection in a sloping forest, Boundary-Layer Meteorology,2003, 108: 397-417.[16]Raupach, M. R., Finnigan, J. J., Brunet, Y., Coherent eddies and turbulence in vegetation canopies: the mixing-Layer analogy,Boundary-Layer Meteorology, 1996, 78:351-382.[17]Zhuang, Y., Amiro, B. D., Pressure fluctuations during coherent motions and their effects on the budgets of turbulent kinetic energy and momentum flux within a forest canopy, Journal Of Applied Meteorology, 1994, 33: 704-711.[18]Shaw, R. H., Zhang, X. J., Evidence of pressure-forced turbulent flow in a forest, Boundary-Layer Meteorology, 1992, 58: 273-288.[19]Maitani, T., Seo, T., Estimates of Velocity-pressure and velocity-pressure gradient interactions in the surface layer over plant canopies, Boundary-Layer Meteorology, 1985, 33: 51-60.[20]Schols, J. L. J., Wartena, L., A dynamical description of turbulent structures in the near neutral atmospheric surface layer: the Role of static pressure fluctuations, Boundary-Layer Meteorology,1986, 34: 1-15.[21]McBean, G. A., Elliott, J. A., The vertical transports of kinetic energy by turbulence and pressure in Boundary Layer, Journal of the Atmospheric Sciences, 1975, 32: 753-765.[22]Wilczak, J. M., Edson, J. B

  5. Abstracts from the 15th International Myopia Conference

    Directory of Open Access Journals (Sweden)

    Alexandra Benavente-Perez

    2016-11-01

    against form deprivation myopia in chickens, by local signaling within the retina Ladan Ghodsi, William K. Stell O14 Contributions of ON and OFF pathways to emmetropization and form deprivation myopia in mice Machelle T. Pardue, Ranjay Chakraborty, Han na Park, Curran S. Sidhu, P. Michael Iuvone O15 Response of the human choroid to defocus Michael J Collins O16 What can RNA sequencing tell us about myopic sclera? Nethrajeith Srinvasalu, Sally A McFadden, Paul N Baird O17 Overview of dopamine, retinal function, and myopia P. Michael Iuvone O18 The eye as a "robust" optical system and myopia Pablo Artal O19 Effect of discontinuation of orthokeratology lens wear on axial elongation in children Pauline Cho, SW Cheung O20 Myopia prevention in Taiwan Pei-Chang Wu O21 Alternatives to ultraviolet light and riboflavin for in vivo crosslinking of scleral collagen Quan V. Hoang, Sally A. McFadden O22 Absence of intrinsically photosensitive retinal ganglion cells (ipRGC alters normal refractive development in mice Ranjay Chakraborty, Duk C. Lee, Erica G. Landis, Michael A. Bergen, Curran Sidhu, Samer Hattar, P. Michael Iuvone, Richard A. Stone, Machelle T. Pardue O23 Scleral micro-RNAs in myopia development and their potential as therapeutic targets Ravi Metlapally O24 Effects of the long-wavelength filtered continuous spectrum on emmetropization in juvenile guinea pigs Ruiqin Li, Qinglin Xu, Hong Zhon, Chenglin Pan, Weizhon Lan, Xiaoning Li, Ling Chen, Zhikuan Yang O25 Ocular and environmental factors associated with eye growth in childhood Scott A. Read O26 Overview- prevention and prediction of myopia and pathologic myopia Seang-Mei Saw O27 New insights into the roles of retinal dopamine in form-deprivation myopia and refractive development in C57BL/6 mice Shi-Jun Weng, Xiao-Hua Wu, Kang-Wei Qian, Yun-Yun Li, Guo-Zhong Xu, Furong Huang, Xiangtian Zhou, Jia Qu, Xiong-Li Yang, Yong-Mei Zhong O28 The effects of the adenosine antagonist, 7-methylxanthine, on refractive development in

  6. A new phase of matter in Oakland

    International Nuclear Information System (INIS)

    Klein, Spencer; Nystrand, Joakim

    2004-01-01

    Recent results from the Relativistic Heavy Ion Collider (RHIC) and the phase diagram of matter at very high energies were the focal points of Quark Matter 2004, held January 10-17, 2004 in the Oakland, California convention center. About 700 participants, including 125 students, from 28 countries gathered for 5 days of plenary and parallel sessions. Besides the scientific discussions, participants enjoyed an afternoon of excursions; choices included visits to San Francisco, the Muir woods, and, of course, a chance to sample Napa Valley wines. There was also a day of introductory lectures for graduate students and a separate afternoon program for 50 local high school teachers. The ''Quark Matter'' conference series has evolved into the premier venue for relativistic heavy ion collisions, and QM2004 was no exception. The 44 plenary and 92 parallel session talks featured a veritable flood of data from STAR (Kai Schweda, LBNL), PHENIX (Tony Frawley, Florida State), PHOBOS (Peter Steinberg, BNL) and BRAHMS (Michael Murray, Kansas), at RHIC. This was accompanied by contributions from HERMES ( Pasquale DiNezza, Frascati) and HERA-B (Joakim Spengler, Heidelberg) and continuing analyses from NA-49 (Marek Gazdzicki, Frankfurt) and NA-57 (Giuseppe Bruno, Bari) at the CERN SPS. The theoretical contributions presented a broad range of models and calculations, from microscopic particle-by-particle simulations to hydrodynamic models that model the bulk behavior using an equation of state. A focus of much discussion was the question ''Have we found the Quark Gluon Plasma (QGP)?'' This search was the prime motivation to build RHIC. Although the RHIC experiments made no formal statement, most conference attendees seemed to feel that the answer was yes. No single measurement makes the case, but the variety of data featured at QM2004 seems most easily explained in the context of a QGP. Some of the signatures included the suppression of high transverse momentum (pT) particles and

  7. Committees and organizers

    Science.gov (United States)

    2011-07-01

    Chairman:Jozef Spałek (Kraków) Program Committee:Stephen Blundell (Oxford), J Michael D Coey (Dublin), Dominique Givord (Grenoble), Dariusz Kaczorowski (Wrocław), Roman Micnas (Poznań), Marek Przybylski (Halle), Ludiwig Schultz (Dresden), Vladimir Sechovsky (Prague), Jozef Spałek (Kraków), Henryk Szymczak (Warszawa), Manuel Vázquez (Madrid) Publication Committee:Dariusz Kaczorowski, Robert Podsiadły, Jozef Spałek, Henryk Szymczak, Andrzej Szytuła Local committee:Maria Bałanda, Anna Majcher, Robert Podsiadły, Michał Rams, Andrzej Ślebarski, Krzysztof Tomala Editors of the Proceedings:Jozef Spałek, Krzysztof Tomala, Danuta Goc-Jagło, Robert Podsiadły, Michał Rams, Anna Majcher Plenary, semi-plenary and tutorial speakers:Ernst Bauer (Wien)Stephen Blundell (Oxford)J Michael D Coey (Dublin)Russell P Cowburn (London)Burkard Hillebrands (Kaiserslautern)Claudine Lacroix (Grenoble)Lluís Mañosa (Barcelona)María del Carmen Muñoz (Madrid)Bernard Raveau (Caen)Pedro Schlottmann (Tallahassee)Frank Steglich (Dresden)Oliver Waldmann (Freiburg) Invited speakers within symposia: R Ahuja (Uppsala)A Kirilyuk (Nijmegen) M Albrecht (Vienna)L Theil Kuhn (Roskilde) K Bärner (Göttingen)J Liu (Dresden) U Bovensiepen (Duisburg)G Lorusso (Modena) V Buchelnikov (Chelyabinsk)M M Maska (Katowice) B Chevalier (Bordeaux)Y Mukovskii (Moscow) O Chubykalo-Fesenko (Madrid)M Pannetier-Lecoeur (Saclay) A V Chumak (Kaiserslautern)G Papavassiliou (Athens) J M D Coey (Dublin)K R Pirota (Campinas) B Dabrowski (DeKalb)P Przyslupski (Warszawa) S Das (Aveiro)M Reiffers (Košice) A del Moral (Zaragoza)K Sandeman (London) V E Demidov (Muenster)D Sander (Halle) B Djafari-Rouhani (Lille)M Sawicki (Sendai/Warsaw) H A Dürr (Menlo Park)J Schaefer (Würzburg) J Fassbender (Dresden)H Schmidt (Wetzikon) J Fontcuberta (Barcelona)J Spałek (Kraków) V Garcia (Orsay)L Straka (Helsinki) J N Gonçalves (Aveiro)A Szewczyk (Warszawa) M E Gruner (Duisburg)Y Taguchi (Wako) G Gubbiotti (Perugia)A Thiaville

  8. Pea seeds (Pisum sativum, faba beans (Vicia fabavar. minor and lupin seeds (Lupinus albus var. multitalia as protein sources in broiler diets: effect of extrusion on growth performance

    Directory of Open Access Journals (Sweden)

    Gianfranco Piva

    2010-01-01

    Full Text Available The effect of extrusion of pea seeds (Pisum sativum (PS, faba bean (Vicia faba, variety minor (FB and lupin seeds (Lupinus albus, variety multitalia (LS on broiler performance were evaluated. Four hundred sixty two 1d-old Ross male chicks, Marek vaccinated, were randomly assigned to seven dietary treatments (3 pens per treatment/22 birds per pen. Chicks were floor housed, ad libitum fed isocaloric and isonitrogenous diets and had free access to water. Artificial light was provided 10 h/d. The bulk of the base diet (control diet was corn (48.8%, 53.7% and 57%, solvent-extracted soy- bean meal (42.8%, 37.3% and 33.4%, corn oil (4.4%, 5.2% and 6.3%, plus synthetic amino acids, minerals, trace minerals and vitamins, respectively for the 1-10d-old, 11-28d-old and 29 to 42d-old growing periods. The amounts of PS, FB and LS used on an as fed basis were: PS and extruded PS (EPS: 353 (1-10d-old, 356 (11-28d-old and 350 (29- 42d-old g/kg; FB and extruded FB (EFB: 479 (1-10d-old, 497 (11-28d-old and 500 (29-42d old g/kg; LS and extrud- ed LS (ELS: 360 (1-10d-old and 300 (11-42d-old g/kg. High levels of pea (350 g/kg and faba bean (500 g/kg did not show negative effects on body weight gain (BWG and bird feed intake compared to control. Lupin at the 300 g/kg level reduced (P< 0.05 the BWG during the finishing period (22 to 42 d, however the effect disappeared over the whole experimental period (1-42 d compared to the control group. The ELS group had a lower (P< 0.01 feed intake com- pared to the control group and to the LS group. The feed conversion rate (FCR was similar among groups for the whole experimental period; however during the grower period the FCR was higher (P< 0.05 for the PS, FB and EFB groups com- pared to the control group. Birds consuming the PS diet had a reduced (P< 0.05 eviscerated carcass yield compared to the control group. The breast meat percent yield was higher (P< 0.01 for birds consuming the FB and EFB diets compared to the control

  9. Dysfunction of the thyroid gland during amiodarone therapy: a study of 297 cases

    Directory of Open Access Journals (Sweden)

    Czarnywojtek A

    2016-04-01

    Full Text Available Agata Czarnywojtek,1,2,* Maria Teresa Płazińska,3,* Małgorzata Zgorzalewicz-Stachowiak,4 Kosma Woliński,1 Adam Stangierski,1 Izabela Miechowicz,5 Joanna Waligórska-Stachura,1 Paweł Gut,1 Leszek Królicki,3 Maja Zioncheck,6 Marek Ruchała1 1Department of Endocrinology, Metabolism and Internal Medicine, 2Department of Pharmacology, Poznan University of Medical Sciences, Poznan, 3Nuclear Medicine Department, Medical University of Warsaw, Warsaw, 4Department of Health Prophylaxis, Laboratory of Medical Electrodiagnostics, 5Department of Computer Science and Statistics, 6Poznan University of Medical Sciences, Poznan, Poland *These authors contributed equally to this work Aim: This study aims to explore and compare the efficacy of radioiodine treatment (RIT in hyperthyroid and euthyroid patients who have been treated with amiodarone (AM in the past or are currently undergoing AM treatment. Clinical observation of a group of patients with amiodarone-induced hypothyroidism during a 12-month follow-up period was used for comparison.Design: This was a observational, two-centered study. Patients were assessed at baseline and at 2 months, 6 months, 8 months, and 12 months after RIT.Patients: Group A: At baseline (61 males [M] and 17 females [F], mean age 50±19 years, there were 78 euthyroid patients with cardiac arrhythmias, who were treated with AM and developed amiodarone-induced thyrotoxicosis, and currently require retreatment with AM. Group B: Hyperthyroid patients (92 M and 26 F, mean age 72±11.8 years after AM therapy in the past. Group C: Hyperthyroid patients (66 M and 13 F, mean age 63.9±13.2 years currently treated by AM. Group D: Hypothyroid patients (6 M and 16 F, mean age 61.4±10.4 years after AM therapy. The patients from Groups A, B, and C were retreated with AM after ~3–6 weeks of RIT.Results: In Group A, after 12 months of RIT therapy, recurrent thyrotoxicosis was observed in six (7.7% cases, and persistent

  10. 6th conference on Advances in Optoelectronics and Micro/nano-optics

    International Nuclear Information System (INIS)

    2017-01-01

    would like to thank all participants of this conference, and particularly the authors of all accepted papers for their high quality and fruitful contributions. We do hope that this volume will be beneficial for readers to their future research endeavours and careers. We also gratefully acknowledge tremendous efforts and dedication of many individuals and all the Editorial Board members in IOP Publishing for their support in producing the proceedings of this event. Sincerely, Yiping Cui Conference Co-Chair CONFERENCE OFFICIALS Conference Co-Chairs Yiping Cui Southeast University, China Xiaocong Yuan Shenzhen University, China Shining Zhu Nanjing University, China Executive Chair Zhuyuan Wang Southeast University, China Technical Program Committee Guanghui Chen China Electronics Technology Group Corporation, China Yiping Cui Southeast University, China Qihuang Gong Peking University, China Min Gu Swinburne University of Technology, Australia Satoshi Kawata Osaka University, Japan Gong-Ru Lin National Taiwan University, Taiwan, China Xu Liu Zhejiang University, China Yanqing Lu Nanjing University, China Ting Mei Northwestern Polytechnical University, China Min Qiu Zhejiang University, China Marek Samoc Wroclaw University of Technology, Poland Colin Sheppard Italian Institute of Technology, Italy Charles Surya Hong Kong Polytechnic University, China Katarina Svanberg Lund University, Sweden Sune Svanberg Lund University, Sweden Jinghua Teng IMRE, Singapore Dinping Tsai Academia Sinica, Taiwan, China Zhuyuan Wang Southeast University, China Jingjun Xu Nankai University, China Baoli Yao Xi’an Institute of Optics and Precision Mechanics, China Xiaocong Yuan Shenzhen University, China Qiwen Zhan University of Dayton, USA Shining Zhu Nanjing University, China (paper)

  11. Foreword

    International Nuclear Information System (INIS)

    Sujkowski, Z.

    2006-01-01

    formation of superconducting regions in layers of MgB 2 obtained by implantation of magnesium ions into a boron substrate followed by intense pulsed plasma treatment, and on the first evidence of ν μ oscillation in an accelerator-based experiment. In the technical category, the winning work was on large scale production of straw tube modules for the LHCb experiment at CERN together with the design of basic hardware modules concerning overall control of this experiment. Another technical achievement was that the system for brachytherapy of brain tumors based on the Photon Needle X-ray generator has entered the phase of clinical testing. Worth mentioning is also the work of our DESY team on the leptoproduction in a nuclear medium as well as that of our KASCADE collaboration participants on the detection and imaging of atmospheric radio flashes from cosmic ray air showers (see Nature 435 (2005) 313) Participation in the EURATOM fusion program was continued. The International Conference Plasma 2005 was organized by our Plasma Physics Department. Our activity in the field of general education and popularization of science has increased. As usual in such cases, we owe this to a few enthusiasts. My thanks for this go to Leszek Nowicki, Jacek Jagielski, Marek Pawlowski, Jacek Szabelski and many others as well as to our Training Department led by Professor Ludwik Dobrzynski. There was a small but significant change in the organization of the Institute: the formation of the Information Technology Division headed by Jacek Szlachciak. This brings a degree of order and expertise into the rapidly developing field with even more rapidly growing needs, possibilities and expectations. We all wish Jacek and his colleagues every successes in carrying out their tasks. The Reader of our Annual Reports may notice a certain novelty in this year's issue: the expanded general part including some details about events which we judge significant. I hope the Reader will find this part as well as the

  12. PLASMA-2013: International Conference on Research and Applications of Plasmas (Warsaw, Poland, 2-6 September 2013)

    Science.gov (United States)

    Sadowski, Marek J.

    2014-05-01

    The PLASMA-2013 International Conference on Research and Applications of Plasmas was held in Warsaw (Poland) from 2 to 6 September 2013. The conference was organized by the Institute of Plasma Physics and Laser Microfusion, under the auspices of the Polish Physical Society. The scope of the PLASMA conferences, which have been organized every two years since 1993, covers almost all issues of plasma physics and fusion research as well as selected problems of plasma technology. The PLASMA-2013 conference topics included: •Elementary processes and general plasma physics. •Plasmas in tokamaks and stellarators (magnetic confinement fusion). •Plasmas generated by laser beams and inertial confinement fusion. •Plasmas produced by Z-pinch and plasma-focus discharges. •Low-temperature plasma physics. •Space plasmas and laboratory astrophysics. •Plasma diagnostic methods and applications of plasmas. This conference was designed not only for plasma researchers and engineers, but also for students from all over the world, in particular for those from Central and Eastern Europe. Almost 140 participants had the opportunity to hear 9 general lectures, 11 topical talks and 26 oral presentations, as well as to see and discuss around 120 posters. From about 140 contributions, after the preparation of about 100 papers and the peer review process, only 74 papers have been accepted for publication in this topical issue. Acknowledgments Acting on behalf of the International Scientific Committee I would like to express our thanks to all the invited speakers and all the participants of the PLASMA-2013 conference for their numerous contributions. In particular, I wish to thank all of the authors of papers submitted for publication in this topical issue of Physica Scripta . Particular thanks are due to all of the reviewers for their valuable reports and comments, which helped to improve the quality of many of the papers. International Scientific Committee Marek J Sadowski, NCBJ

  13. In Ovo Vaccination with Turkey Herpesvirus Hastens Maturation of Chicken Embryo Immune Responses in Specific-Pathogen-Free Chickens.

    Science.gov (United States)

    Gimeno, Isabel M; Faiz, Nik M; Cortes, Aneg L; Barbosa, Taylor; Villalobos, Tarsicio; Pandiri, Arun R

    2015-09-01

    Administration of Marek's disease (MD) vaccines in ovo has become a common practice for the poultry industry. Efficacy of MD vaccines is very high, even though they are administered to chicken embryos that are immunologically immature. We have recently demonstrated that in ovo vaccination with turkey herpesvirus (HVT) results in increased activation of T cells at hatch. Our previous results suggested that in ovo vaccination with HVT might have a positive impact not only on MD protection but also on the overall maturity of the developing immune system of the chicken (Gallus gallus domesticus). The objective of this study was to evaluate the effect of administration of HVT at 18 days of embryonation (ED) on the maturation of the embryo immune system. Four experiments were conducted in Specific-Pathogen-Free Avian Supplies (SPAFAS) chickens to evaluate the effect of administration of HVT at 18 ED on the splenic cell phenotypes at day of age (experiment 1) and on the ability of 1-day-old chickens to respond to various antigens compared with older birds (experiments 2 and 3). In addition, a fourth experiment was conducted to elucidate whether administration of other serotype's MD vaccines (CVI988 and SB-1) at 18 ED had the same effect as HVT on the spleen cell phenotypes at day of age. Our results demonstrated that 1-day-old chickens that had received HVT in ovo (1-day HVT) had higher percentages of CD45+, MHC-I+, CD45+MHC-I+, CD3+, MHC-II+, CD3+MHC-II+, CD4+, CD8+, and CD4+CD8+ cells in the spleen than 1-day-old sham-inoculated chickens (1-day sham). Moreover, spleens of 1-day HVT chickens had greater percentages of CD45+MHC-I+ cells and equal or greater numbers of CD4+CD8- and CD4-CD8+ cells than older unvaccinated chickens. In addition, administration of HVT at 18 ED rendered chicks at hatch more responsive to unrelated antigens such as concavalin A, phytohemagglutinin-L, and keyhole limpet hemocyanin. Administration of MD vaccines of other serotypes had an effect

  14. PREFACE: 12th International Symposium on Multiscale, Multifunctional and Functionally Graded Materials (FGM 2012)

    Science.gov (United States)

    Zhou, Zhangjian; Li, Jingfeng; Zhang, Lianmeng; Ge, Changchun

    2013-03-01

    Technology, and was supported by National Natural Science Foundation of China. On behalf of the organizing committee of FGM-2012, I express my great appreciation to their support of the symposium. Nearly 100 scholars and students from Japan, Brazil, Germany, Russia, United States of America, Portugal, France, Switzerland, Turkey, Singapore, China, and so on, attended FGM-2012, and 57 of the presented papers were collected and selected for publication. The subjects of these papers cover simulation and characterization, advanced fabrication technology, novel application of FGM and layer materials. I cordially thank all of the authors and attendees for their support, and my appreciation is also given to the advisory committee, organizing committee, and the conference volunteers for their hard work. Professor Zhangjian Zhou Proceedings Editor Beijing, December 2012 Committees International Advisory Committee Professor Glaucio H Paulino, USA Professor Marek-Jerzy Pindera, USA Professor Jeong-Ho Kim, USA Professor Emer Fazil Erdogan, USA Professor Dr Monika Willert-Porada, Germany Professor Emer Wolfgang G J Bunk, Germany Professor Omer Van Der Biest, Belgium Professor Michael M Gasik, Finland Professor Evgeny Levashov, Russia Professor Lianmeng Zhang, China Professor Qingjie Zhang, China Professor Wei Pan, China Professor Chang-Chun Ge, China Professor Jing-Feng Li, China Professor Zhangjian Zhou, China Associate Professor Serkan Dag, Turkey Professor Fernando A Rochinha, Brazil Professor Emilio C N Silva, Brazil Professor Luis August Rocha, Portugal Dr Sasa Novak, Slovenia Dr Masayuki Niino, Japan Professor Akira Kawasaki, Japan Professor Ichiro Shiota, Japan Dr Akinaga Kumakawa, Japan Dr Yoshikazu Shinohara, Japan Professor Kiyotaka Matsuura, Japan Professor Yoshinari Miyamoto, Japan Professor Takashi Goto, Japan Professor Yoshimi Watanabe, Japan Professor Kazuhiro Hasezaki, Japan Professor Soshu Kirihara, Japan Professor Emer Toshio Hirai, Japan Mr Choji Endou, Japan Dr

  15. PREFACE: EDS2010 Preface

    Science.gov (United States)

    Heggie, Malcolm I.

    2011-03-01

    the afternoon outing to Arundel Castle and dinner in the evening at Wiston House, a mansion of Tudor origin near Steyning, West Sussex. So a short audience-participation seminar was held in the conference room of the manor, covering the history of dislocations and the history of the conference series. We were also able to extend the appreciation of the life of Prof. Yuri Ossipyan (15 Feb 1931 - 10 Sep 2008) briefly given at EDS2008. EDS2010 continued the drive into graphene-based materials with a session devoted to them, and it gave immense pleasure to many of us who were his former students to dedicate a session to the work of Professor R Jones. We are grateful to his present and former co-workers who came and presented an impressive perspective on their work with him and a vision of a vigorous future for him in his retirement and for AIMPRO, the current Density Functional Theory code that derives from the one he established with his former student, Dr Patrick Briddon. For EDS2010 we made two minor modifications to the appearance of the conference: a central webpage www.eds-conferences.org, ably managed by our webmaster, Dr Gemma Haffenden, and a Facebook page, "EDS conference series", which Dr Amy Gandy runs enthusiastically. Amongst other things the conference photographs appear here. "I like this". In fact, currently 22 FB-ers "like this" and I am sure it will grow. Finally, it is a pleasure to acknowledge the significant contributions of Co-Chair, Prof. Marek Skowronski, Conference Manager, Dr Christopher Latham, and the editors of this volume, Drs Jon Goss and Chris Ewels, who in turn wish to thank Dr Alexis Vlandas for his help proof reading the articles. We all wish the best of luck to Prof. Philomela Khomninou and her team in the organisation of EDS2012.

  16. Nitrous oxide fluxes from forest floor, tree stems and canopies of boreal tree species during spring

    Science.gov (United States)

    Haikarainen, Iikka; Halmeenmäki, Elisa; Machacova, Katerina; Pihlatie, Mari

    2017-04-01

    were 1.4 and 2.2 mg N2O ha-1 h-1, respectively, while the forest floor was a sink of -6.1 mg N2O ha-1 h-1. At the mineral soil site the upscaled N2O emissions from birch trees and forest floor were 3.6 and 8.9 mg N2O ha-1 h-1, respectively, indicating that the emissions from trees significantly contribute to the N2O emissions from boreal forests. The results also indicate that tree canopies contributed up to 89% of the whole-tree N2O emissions. Our findings demonstrate that we urgently need more studies focusing on leaf-level N2O exchange in forest ecosystems. Acknowledgement This research was financially supported by the National Programme for Sustainability I (LO1415), Czech Science Foundation (17-18112Y), ENVIMET (CZ.1.07/2.3.00/20.0246) , Emil Aaltonen Foundation, Academy of Finland Research Fellow projects (292699, 263858, 288494), The Academy of Finland Centre of Excellence (projects 1118615, 272041), and ICOS-Finland (281255). We thank Hyytiälä SMEAR II station staff and Marek Jakubik for technical support.

  17. Proceedings of the International Symposium on Topological Aspects of Critical Systems and Networks

    Science.gov (United States)

    Yakubo, Kousuke; Amitsuka, Hiroshi; Ishikawa, Goo; Machino, Kazuo; Nakagaki, Toshiyuki; Tanda, Satoshi; Yamada, Hideto; Kichiji, Nozomi

    2007-07-01

    I. General properties of networks. Physics of network security / Y.-C. Lai, X. Wand and C. H. Lai. Multi-state interacting particle systems on scale-free networks / N. Masuda and N. Konno. Homotopy Reduction of Complex Networks 18 / Y. Hiraoka and T. Ichinomiya. Analysis of the Susceptible-Infected-Susceptible Model on Complex Network / T. Ichinomiya -- II. Complexity in social science. Innovation and Development in a Random Lattice / J. Lahtinen. Long-tailed distributions in biological systems: revisit to Lognormals / N. Kobayashi ... [et al.]. Two-class structure of income distribution in the USA:exponential bulk and power-law tail / V. M. Yakovenko and A. Christian Silva. Power Law distributions in two community currencies / N. Kichiji and M. Nishibe -- III. Patterns in biological objects. Stoichiometric network analysis of nonlinear phenomena in rection mechanism for TWC converters / M. Marek ... [et al.]. Collective movement and morphogenesis of epithelial cells / H. Haga and K. Kawabata. Indecisive behavior of amoeba crossing an environmental barrier / S. Takagi ... [et al.]. Effects of amount of food on path selection in the transport network of an amoeboid organism / T. Nakagaki ... [et al.]. Light scattering study in double network gels / M. Fukunaya ... [et al.].Blood flow velocity in the choroid in punctate inner choroidopathy and Vogt-Koyanagi-Harada disease; amd multifractal analysis of choroidal blood flow in age-related macular degeneration / K. Yoshida ... [et al.]. Topological analysis of placental arteries: correlation with neonatal growth / H. Yamada and K. Yakubo -- IV. Criticality in pure and applied physics. Droplets in Disordered Metallic Quantum Critical Systems / A. H. Castro Neto and B. A. Jones. Importance of static disorder and inhomogeneous cooperative dynamics in heavy-fermion metals / O. O. Bernal. Competition between spin glass and Antiferromagnetic phases in heavy fermion materials / S. Sullow. Emergent Phases via Fermi surface

  18. Research for energy optimized building. Status seminar; Forschung fuer Energieoptimiertes Bauen. Statusseminar

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    Within the meeting of the Project Management Juelich (Juelich, Federal Republic of Germany) and the Bavarian Centre for Applied Energy Research (Wuerzburg, Federal Republic of Germany) between 30th June and 2nd July, 2009, in Wuerzburg the following lectures were held: (1) Optically switchable layers with tungsten oxide (Andreas Georg); (2) Functional coatings for application on outer surfaces of glazings (Hansjoerg Weis); (3) Functional coatings and application (Thomas Hofmann); (4) Thermal insulation in the 21st century: Vacuum-insulation panel and vacuum-isolation glasses (Ulrich Heinemann, Helmut Weinlaeder, Hans-Peter Ebert); (5) Textile composites using thermal insulation composites as an example (Alexandra Saur, Jan Beringer, Andreas Holm, Klaus Sedlbauer); (6) Design of membranes for the enhancement of the energy efficiency in buildings (Jochen Manara et al.); (7) Design of membranes for the energetic sanitation of buildings (Werner Lang et al.); (8) Total energetic analysis of complex HLK systems for buildings (Wolfgang Richter); (9) Review on hybrid aeration systems (Dirk Mueller et al.); (10) IEA SHC-Task 38 (Operating Agent) - Energy efficient cooling and dehumidification (ECOS) (Hans-Martin Henning, Alexander Morgenstern, Constanze Bongs); (11) Air quality controlled aeration of building (Jens Knissel, Marc Grossklos); (12) Development of a solar driven refrigerating absorber / heat pump with a ice storage (Thomas Brendel, Marco Zetzsche, Hans Mueller-Steinhagen); (13) Heat pumps field test 'WP efficiency' - interim results (Marek Miara); (14) ECBCS Annex 49 Low Exergy Systems for High-Performance Buildings and Communities (Dietrich Schmidt, Marlen Schurig); (15) Aquifer storage for the heat supply and cold supply of buildings (Sefan Kranz et al.); (16) Evaluation and optimization of operation of systems for the seasonal heat storage and cold storage in the foundations of office buildings (Herdis Kipry, Franziska Bockelmann, M. Norbert Fisch

  19. Prospective unmasked randomized evaluation of the iStent inject® versus two ocular hypotensive agents in patients with primary open-angle glaucoma

    Directory of Open Access Journals (Sweden)

    Fea AM

    2014-05-01

    Full Text Available Antonio M Fea,1 Jose I Belda,2 Marek Rękas,3 Anselm Jünemann,4 Lydia Chang,5 Luis Pablo,6 Lilit Voskanyan,7 L Jay Katz81Università degli Studi di Torino, Clinica Oculistica, Torino, Italy; 2Hospital Torrevieja Salud, UTE, Servicio de Oftalmologia, Alicante, Spain; 3Military Institute of Medicine, Department of Ophthalmology, Warsaw, Poland; 4Universitätsaugenklinik, Erlangen, Germany; 5Hinchingbrooke Hospital NHS Trust and Moorfields Bedford Hospital NHS Trust, United Kingdom; 6Hospital Universitario Miguel Servet, Servicio Oftalmologico, Zaragoza, Spain; 7SV Malayan Ophthalmological Center, Yerevan, Armenia; 8Wills Eye Institute, Jefferson Medical College, Philadelphia, PA, USAPurpose: The purpose of this study was to compare outcomes of subjects with open-angle glaucoma (OAG not controlled on one medication who underwent either implantation of two iStent inject® trabecular micro-bypass devices or received medical therapy consisting of a fixed combination of latanoprost/timolol.Patients and methods: Of 192 subjects who qualified for the study and were enrolled, 94 were randomized to surgery with implantation of two iStent inject® devices in the treated eye and 98 to receive medical therapy.Results: At the month 12 visit, 94.7% of eyes (89/94 in the stent group reported an unmedicated intraocular pressure (IOP reduction of ≥20% versus baseline unmedicated IOP, and 91.8% of eyes (88/98 in the medical therapy group reported an IOP reduction ≥20% versus baseline unmedicated IOP. A 17.5% between-group treatment difference in favor of the iStent inject group was statistically significant (P=0.02 at the ≥50% level of IOP reduction. An IOP ≤18 mmHg was reported in 92.6% of eyes (87/94 in the iStent inject group and 89.8% of eyes (88/98 in the medical therapy group. Mean (standard deviation IOP decreases from screening of 8.1 (2.6 mmHg and 7.3 (2.2 mmHg were reported in the iStent inject and medical therapy groups, respectively. A high

  20. Literature Review of Bozhou Tusi Studies (2001-2013)

    Institute of Scientific and Technical Information of China (English)

    LI Yueping

    2014-01-01

    Based on the topic of the “Bozhou Tusi”, we obtained 35 publications of Chinese journals from the China Academic Journal Network Publishing Database ( 2001 -2013 ) .This article will review and make some comments on all of the literature of Bozhou Tusi Studies from different per-spectives . I.Studies from the Perspective of History 1.Historical Vicissitude History is a long process .From the perspec-tive of history , we know how the name of Weng'an came into being;the formation and historical func-tions of the Tusi system in Bozhou; Yang Ying -long's rebellion and its process; the historical background and the influence of the Ping Bo Bat-tle; the documents about the Ping Bo War and their historical value; and the historical geograph-ical study on the placename of “Hai Long Tun”. 2.Historic People When we talk about historical vicissitude and its development , we must talk about those historic people and their important functions in the histori-cal vicissitude and their development .These im-portant people had “epoch -making” historic function .If there had not been these people and their great achievements , relevant histories and historical events would be have to be rewritten . These important people include Qin Liangyu , the Yang's, the Tian's, Yang Yinglong, and so on. We must take the viewpoint of the historical mate-rialism dialectic to comment on these historic peo-ple, and only by doing so , can we get the right e-valuations and conclusions , or we would only get biased conclusions . II.Studies from the Perspective of Society 1 .Social Systems Social systems were a product of social devel-opment.The Tusi system was a product of social development during a certain historical stage in China .During this historical stage , it played an active role in the fields of social security , econo-my, military, life and other aspects under their control in the regions .In the same way , all of the Yang Tusi played a positive part in all of these as

  1. Reactor Dosimetry State of the Art 2008

    Science.gov (United States)

    Voorbraak, Wim; Debarberis, Luigi; D'Hondt, Pierre; Wagemans, Jan

    2009-08-01

    Oral session 1: Retrospective dosimetry. Retrospective dosimetry of VVER 440 reactor pressure vessel at the 3rd unit of Dukovany NPP / M. Marek ... [et al.]. Retrospective dosimetry study at the RPV of NPP Greifswald unit 1 / J. Konheiser ... [et al.]. Test of prototype detector for retrospective neutron dosimetry of reactor internals and vessel / K. Hayashi ... [et al.]. Neutron doses to the concrete vessel and tendons of a magnox reactor using retrospective dosimetry / D. A. Allen ... [et al.]. A retrospective dosimetry feasibility study for Atucha I / J. Wagemans ... [et al.]. Retrospective reactor dosimetry with zirconium alloy samples in a PWR / L. R. Greenwood and J. P. Foster -- Oral session 2: Experimental techniques. Characterizing the Time-dependent components of reactor n/y environments / P. J. Griffin, S. M. Luker and A. J. Suo-Anttila. Measurements of the recoil-ion response of silicon carbide detectors to fast neutrons / F. H. Ruddy, J. G. Seidel and F. Franceschini. Measurement of the neutron spectrum of the HB-4 cold source at the high flux isotope reactor at Oak Ridge National Laboratory / J. L. Robertson and E. B. Iverson. Feasibility of cavity ring-down laser spectroscopy for dose rate monitoring on nuclear reactor / H. Tomita ... [et al.]. Measuring transistor damage factors in a non-stable defect environment / D. B. King ... [et al.]. Neutron-detection based monitoring of void effects in boiling water reactors / J. Loberg ... [et al.] -- Poster session 1: Power reactor surveillance, retrospective dosimetry, benchmarks and inter-comparisons, adjustment methods, experimental techniques, transport calculations. Improved diagnostics for analysis of a reactor pulse radiation environment / S. M. Luker ... [et al.]. Simulation of the response of silicon carbide fast neutron detectors / F. Franceschini, F. H. Ruddy and B. Petrović. NSV A-3: a computer code for least-squares adjustment of neutron spectra and measured dosimeter responses / J. G

  2. EDITORIAL: Greetings from the new Editor-in-Chief Greetings from the new Editor-in-Chief

    Science.gov (United States)

    Nielsch, Kornelius

    2012-01-01

    -review, with the aim to raise the quality of our content, three years later the number of published articles has remained stable at around 220 per year, whilst the number of downloads and citations to the journal has grown. In 2011, three topical issues have been published, on: (Nano)characterization of semiconductor materials and structures (Guest Editor: Alberta Bonanni, University of Linz, Austria) Flexible OLEDs and organic electronics (Guest Editors: Jang-Joo Kim, Min-Koo Han, Cambridge University, UK, and Yong-Young Noh, Seoul National University, Korea) From heterostructures to nanostructures: an 80th birthday tribute to Zhores Alferov (Guest Editor: Dieter Bimberg, Technische Universität Berlin, Germany) For the coming years, I will strongly support that the number of published topical issues will continue on the same level or slightly rise. SST has planned the publication of the following topical issues for 2012: Non-polar and semipolar nitride semiconductors (Guest Editors: Jung Han, Yale University, USA, and Michael Kneissl, Technische Universität Berlin, Germany) Topological insulators (Guest Editors: Alberto Morpurgo, Université de Genève, Switzerland and Björn Trauzettel, Universität Basel, Switzerland) Atomic layer deposition (Guest Editor: Marek Godlewski, Polish Academy of Sciences, Poland) 50th Anniversary of the laser diode (Guest Editors: Mike Adams, Univeristy of Essex, UK and Stephane Calvez, University of Strathclyde, UK) In addition to the traditional topics of SST, I as Editor-in-chief, strongly support and welcome the submission of manuscripts on organic semiconductors, topological insulators, semiconductor nanostructures for photovoltaic, solid-state lighting and energy harvesting, IC application beyond Moore's law and fundamental works on semiconductors based on abundant materials. I am extremely optimistic about the future of SST. I believe that we will raise the standards of acceptance while maintaining the short time from submission to

  3. Executive Summary - Overview

    International Nuclear Information System (INIS)

    2005-01-01

    Professor Andrzej Budzanowski was Director of IFJ in the years 1990-2004. On September 1st 2004, on IFJ joining the Polish Academy of Sciences, Professor Marek Jezabek has been nominated by the President of PAN as the Director of IFJ, for a 4-year term. Our Institute, with a personnel of 450 (182 research staff) and over 50 Ph.D. students, is presently one of the largest institutes of the Polish Academy of Sciences and one of the largest research institutes in Poland. The scientific staff consists on 120 post-doctoral researchers, 26 Associated Professors and 36 State-Nominated Professors. The total budget of the Institute for the year 2004 was about 56 million Euro. The IFJ is financed mainly from the state budget of the Ministry of Scientific Research and Information Technology. In 2004 this financing was about 4 million Euro, constituting 72% of the Institute's total budget. The remaining part of our 2004 budget came from individual research projects, also sponsored by the Ministry of Scientific Research (688 kEuro), from international projects (368 kEuro) and from the Institute's entrepreneurship activities (498 kEuro). Between 2003 and 2004 we doubled our income from international projects. For further budget information. The Scientific Council of the Institute, which consists of 40 elected members of the Institute's staff and 4 external members (elected representatives from other Polish institutes and universities), is authorized to confer Ph.D. degrees in Physics and related disciplines, and to initiate and conduct habilitation and professorship procedures. In 2003-2004 17 Ph.D. theses and 11 habilitations have been completed. Following their review procedures, 3 Associate Professors at the IFJ became state-nominated Professors, receiving their nominations from Poland's President, Mr. A. Kwasniewski. The Institute is structured into 17 scientific departments which cover the range of our scientific interests. A summary of our main scientific achievements in

  4. Foreword

    International Nuclear Information System (INIS)

    Wrochna, G.

    2010-01-01

    -XFEL). The Polish parliament ratified the XFEL convention and IPJ was nominated to represent Poland as the E-XFEL GmbH shareholder. Most of the 21 mln EUR of the Polish contribution will be provided in-kind. This includes elements of the accelerator delivered by our institute. IPJ was also granted over 4 mln EUR to provide Neutral Beam Injection elements for the stellarator (thermonuclear reactor) W7-X being built in Greifswald, Germany. Our experts are participating in the design of the European Spallation Source in Lund, Sweden. We are also considering contributions to other large research projects in Europe, especially those from the ESFRI roadmap. Development of new technologies resulted in 2010 in a few patent proposals. A method of surface modification by ion beams to make better forms for the production of rubber elements was given an award at international exhibition ITEX in Kuala Lumpur. It was a joint development with the Institute of Electronic Materials Technology (ITME) in Warsaw and the Institute for Engineering of Polymer Materials and Dyes (IMPiB) in Torun. Another award was given at the International Exhibition of Innovations in Warsaw to IPJ and the Techtra company for a new detector for non-destructive industrial radiography. An important element of the mission of our institute is to share the excitement of front-line research with the general public. It is not easy, however, for scientists to meet the demands of the media to present in just a few sentences the essence of a sophisticated theory or an advanced technology. This changed when dr Marek Pawlowski was appointed the IPJ Spokesman. Journalists appreciated his role in bridging the gap between scientists and the media and granted him a special award in the '' Science Popularizer of the Year 2010 '' contest. In the perspective of implementing nuclear power in Poland, society requires quite detailed information on this subject, given in an understandable way. This is the mission of our Department of

  5. PREFACE: Quantum dots as probes in biology

    Science.gov (United States)

    Cieplak, Marek

    2013-05-01

    photosynthetic systems. The next paper, by Olejnik et al, discussed metallic QDs which enhance photosynthetic function in light-harvesting biomolecular complexes. Such hybrid structures with gold QDs are shown to exhibit a strong increase in the fluorescence quantum yield. The next two papers, by Sikora et al and Kaminska et al deal with the ZnO nanoparticles passivated by MgO. In the first of these two papers, the authors describe the behavior of ZnO/MgO when introduced to human cancer cells. In the second, the authors describe the QDs with an extra outer layer of Fe2O3 which makes the nanoparticles superparamagnetic and also capable of generation of reactive oxygen species which could be applied to form localized centers of toxicity for cancer treatment. Finally, in the last paper by Yatsunenko et al, the authors discuss several semiconducting QDs like ZnO with various rare-earth dopands. They propose a microwave-driven hydrothermal technology to make them, characterize their luminescence and demonstrate their usefulness in the early recognition of cancer tissues. Quantum dots as probes in biology contents Quantum dots as probes in biologyMarek Cieplak Luminescent nanoparticles and their applications in the life sciencesVarun K A Sreenivasan, Andrei V Zvyagin and Ewa M Goldys Ferredoxin:NADP+ oxidoreductase in junction with CdSe/ZnS quantum dots: characteristics of an enzymatically active nanohybrid Krzysztof Szczepaniak, Remigiusz Worch and Joanna Grzyb Spectroscopic studies of plasmon coupling between photosynthetic complexes and metallic quantum dotsMaria Olejnik, Bartosz Krajnik, Dorota Kowalska, Guanhua Lin and Sebastian Mackowski Luminescence of colloidal ZnO nanoparticles synthesized in alcohols and biological application of ZnO passivated by MgOBożena Sikora, Krzysztof Fronc, Izabela Kamińska, Kamil Koper, Piotr Stępień and Danek Elbaum Novel ZnO/MgO/Fe2O3 composite optomagnetic nanoparticles I Kamińska, B Sikora, K Fronc, P Dziawa, K Sobczak, R Minikayev, W

  6. „To nie była Ameryka”. Z Michaelem Charlesem Steinlaufem rozmawia Elżbieta Janicka (Warszawa – Nowy Jork – Warszawa, 2014–2015

    Directory of Open Access Journals (Sweden)

    Elżbieta Janicka

    2016-01-01

    Full Text Available “This was not America.” Michael Charles Steinlauf in conversation with Elżbieta Janicka (Warsaw – New York – Warsaw, 2014–2015 Born in Paris in 1947, Michael Charles Steinlauf talks about his childhood in New York City, in the south of Brooklyn (Brighton Beach, in a milieu of Polish Jewish Holocaust survivors. His later experiences were largely associated with American counterculture, the New Left, an anti-war and antiracist student movement of the 1960s (Students for a Democratic Society, SDS as well as the anticapitalist underground of the 1970s (“Sunfighter”, “No Separate Peace”. In the 1980s, having undertaken Judaic Studies at Brandeis University, Steinlauf arrived in Poland, where he became part of the democratic opposition circles centred around the Jewish Flying University (Żydowski Uniwersytet Latający, ŻUL. In the independent Third Republic of Poland, he contributed to the creation of the Museum of the History of Polish Jews in Warsaw. Michael C. Steinlauf’s research interests focus on the work of Mark Arnshteyn (Andrzej Marek and of Yitskhok Leybush Peretz, Yiddish theatre as well as Polish narratives of the Holocaust. The latter were the subject of his monograph Bondage to the dead: Poland and the memory of the Holocaust (1997, Polish edition 2001 as Pamięć nieprzyswojona. Polska pamięć Zagłady. An important topic of the conversation is the dispute concerning the categories used to describe the Holocaust, including the conceptualisation of Polish majority experience of the Holocaust as a collective trauma. Controversies also arise in connection with the contemporary phenomena popularly conceptualised as the “revival of Jewish culture in Poland” and “Polish–Jewish dialogue.”  Another subject of the conversation is Michał Sztajnlauf (1940–1942, Michael C. Steinlauf’s stepbrother. The fate of the brothers was introduced into the canon of Polish culture by Hanna Krall’s short story Dybuk

  7. Foreword

    International Nuclear Information System (INIS)

    Sujkowski, Z.

    2001-01-01

    in the ''knee region'' (10 15 - 10 17 ) eV from the cosmic showers (the KASCADE collaboration) or inquire the Nature about the possible correlation of some cosmic radiation with the solar activity. One front-line in the low energy nuclear physics nowadays is the quest for the heaviest nuclear species - one of the specialities of our theory group. This group is known for its close contacts with experimentalists around the world. Recently, they highlighted these contacts by suggesting a new method to improve the mass determination for heavy nuclides from the Schottky noise signals in a storage ring. We move on to the plasma physics. The physics of the fourth state of matter, dominating in the Universe, the physics of non-linear phenomena, the physics of the XXI century. The physics closely linked to nuclear sciences and yet distinctly different. The physics which has numerous technological spin-offs, be it because of the experimental techniques it develops or of the phenomena it discovers. It is good to see that we are strongly entrenched in this field and have justified appetites for more. We focus now on the materials science done with nuclear techniques. We are pleased to note that our implantation techniques develop well and are now applied to e.g. hardening the steel edges. And we brag a bit about our latest work on the new crystallographic forms of uranium compounds after having done experiments we now propose explanations. The experimental physicist needs detectors. Ever better, bigger, more sophisticated. We have a strong group pursuing this improvement task, especially with respect to the scintillators. It was rewarding to learn that the international community has appreciated this effort. The appreciation came from the IEEE/Nuclear and Plasma Science Society with the award of their prestigious prize ''to Marek Moszynski for outstanding contributions to the modern scintillation detector and its application in physics experiment, nuclear medicine and other

  8. Getting an Answer Right

    Science.gov (United States)

    Moore, John W.

    1999-07-01

    really is.) Or we could ask students to make careful observations as an experiment is being carried out and then decide whether the proposed interpretation was correct. (If the only effect of burning a candle in a beaker inverted in a water bath is to use up the oxygen, then the water should rise slowly and steadily into the beaker as long as the candle burns; it does not.) Getting the right answer is not nearly as important as getting an answer right- exploring and experimenting to eliminate alternative hypotheses and finding the best-supported explanation. Diffusion and the fraction of oxygen in air can be studied with simple, inexpensive equipment, and it is easy for students to experiment with them. If we use them appropriately, these two subjects have great potential for enhancing students' skills in critical thinking and experimental design. Many other phenomena reported in these pages provide similar opportunities. Let's apply our ingenuity and effort to making the most of them. Literature Cited 1. Parsons, L. J. Chem. Educ. 1999, 76, 898. 2. Birk, J. P.; Lawson, A. E. J. Chem. Educ. 1999, 76, 914. 3. Mason, E. A.; Kronstadt, B. J. Chem. Educ. 1967, 44, 740. Kirk, A. D. J. Chem. Educ. 1967, 44, 745. 4. Davis, L. C. J. Chem. Educ. 1996, 73, 824. 5. Westbrook, S.; Marek, E. A. J. Res. Sci. Teach. 1991, 28, 649-660 6. Birk, J. P.; McGrath, L.; Gunter, S. K. J. Chem. Educ. 1981, 58, 804.

  9. Editorial

    Directory of Open Access Journals (Sweden)

    Dana Kapitulčinová

    2013-12-01

    Sciences, Philosophy, and Theology (Reviewed Paper by Zuzana Svobodová. This philosophical text analyses the work of Josef Petr Ondok – Czech theologian, philosopher and biologist – from the perspective of ethics and ecoethics. 4 The Purpose of Education: Australian and Slovenian perspectives in Education for Sustainability (Inspiration by Phil Smith and Majda Naji. The authors present their view on the purpose of education in the context of sustainable development and include examples of education for sustainable development from their countries – Slovenia and Australia. 5 Environmental mining limits in the North Bohemian Lignite Region. Book review: Říha, M., Stoklasa, J., Lafarová, M., Dejmal, I., Marek, J., Pakosta, P., Beránek, K. Environmental mining limits in the North Bohemian Lignite Region. Společnost pro krajinu, Praha 2005. Translation: Petr Kurfürst. This book review written by Andrew Barton looks at the issue of mining limits in the region of North-West Bohemia in the Czech Republic and briefly summarises from the content of the book originally published in 2005 (in Czech, but later translated into English supplemented with the most up-to-date information on the current situation. 6 Informational texts: A very interesting article on environmental literacy by Petr Daniš, originally published as a reviewed article in Czech (Envigogika 3/2013, has been translated into English and is now available to our readers. School teachers might be interested in the announcement of a school essay competition run by The Living Rainforest, a UK-based charity. 7 Related announcements: As we feel that dialogue on environmental education and ESD related issues in CZ should be promoted nationally and internationally, this time we are publishing two issues simultaneously (for the content of the Czech issue of Envigogika, see here. We wish you inspirational reading and a peaceful Christmas holiday, as well as a successful New Year. The Envigogika editorial team In

  10. 6th International Symposium on Molecular Allergology (ISMA

    Directory of Open Access Journals (Sweden)

    Christiane Hilger

    2016-10-01

    -allergic humans Almedina Kurtaj, Christoph Hillebrand, Gerda Fichtinger, Martin Danzer, Christian Gabriel, Theresa Thalhamer, Sandra Scheiblhofer, Josef Thalhamer, Richard Weiss P4 Analyzing the cross-reactivity profile of the major ragweed allergen Amb a 1 Martin Wolf, Michael Hauser, Ulrike Pichler, Teresa Twaroch, Gabriele Gadermaier, Christof Ebner, Hidenori Yokoi, Toshiro Takai, Alain Didierlaurent, Adriano Mari, Peter Briza, Heidrun Behrendt, Angela Neubauer, Frank Stolz, Fátima Ferreira, Michael Wallner P5 LTP (Pru p 3 sensitisation in skin prick test: which means in clinical practice? Sara Carvalho, Tatiana Lourenço, Joana Cosme, Fátima Cabral Duarte, Amélia Spínola Santos, Ana Célia Costa, Manuel Pereira Barbosa P6 IgE profiles, allergen exposure and lifestyle of 501 Austrian pupils: investigation of influences on the development of allergic sensitizations Teresa Stemeseder, Eva Klinglmayr, Bettina Schweidler, Lisa Lueftenegger, Stephanie Moser, Patrick Doppler, Roland Lang, Martin Himly, Gertie J. Oostingh, Arne Bathke, Joerg Zumbach, Thomas Hawranek, Gabriele Gadermaier P7 Molecular profiles of sensitization to perennial inhalant allergens in a middle European region Petr Panzner, Martina Vachova, Tomas Vlas, Marek Maly P8 Evolution of the IgE response to house dust mite allergen molecules in childhood Daniela Posa, Serena Perna, Stephanie Hofmaier, Laura Hatzler, Alexander Rohrbach, Carl-Peter Bauer, Ute Hoffmann, Johannes Forster, Fred Zepp, Antje Schuster, Philippe Stock, Ulrich Wahn, Linus Grabenhenrich, Thomas Keil, Susanne Lau, Kuan-Wei Chen, Yvonne Resch, Susanne Vrtala, Rudolf Valenta, Paolo Maria Matricardi P9 Tropomyosin (Pen a1: to include or not to include in skin prick testing? Joana Cosme, Sara Carvalho, Tatiana Lourenço, Amélia Spínola Santos, Manuel Pereira Barbosa Immunoallergy Department - Hospital de Santa Maria – Centro Hospitalar Lisboa Norte, Lisbon, Portugal, Lisbon, Portugal; Immunoallergy Department - Hospital de Santa Maria