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Sample records for lu yanfei gao

  1. Analysis of Gao Jia-lin's life tragedy in Lu Yao's"life"%路遥《人生》中高加林人生悲剧的分析

    Institute of Scientific and Technical Information of China (English)

    杜刚秀

    2013-01-01

    Gao Jia-lin personality is very complex, is shape the classic literary by Lu Yao, but also the Chinese contemporary literature in the gallery of immortal images. Gao Jia-lin want to realize their own value, want to have a bright future and perfect love, and therefore exhibit an extraordinary entrepreneurial spirit, but ultimately failed to keep the faith and his principles, resulting in his pursuit of all ended in failure, his life is full of tragic color. A careful analysis of the novel, can be found the cause of Gao Jia-lin's life tragedy both factors of society, and his own personal factor.%高加林的性格十分复杂,是路遥塑造的经典的文学典型,同时也是中国当代文学画廊中不朽的文学形象。高加林想要实现自身的价值,想拥有美好的前程与完美的爱情,并且为此表现出非凡的进取精神,但是高加林最终没有能坚守自己的信念与原则,致使他的这些追求均以失败而告终,他的人生充满了悲剧色彩。认真分析小说,可以发现造成高加林人生悲剧的原因既有社会层面的因素,又有他个人的因素。

  2. Gao Fenglian and Her Papercuts

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The papercuts of Gao Fenglian, a northern Shanxi woman, are collected by Chinese and foreign galleries, museums and individuals. For a time, it has been a hot topic in her hometown. When she returned from the UN Fourth World Conference on Women, the rural woman who has lived on the Loess Plateau for dozens of years was admired by her fellow villagers. The scissors gave the hardworking woman infinite delight

  3. 4 CFR 83.7 - GAO policy and requirements.

    Science.gov (United States)

    2010-01-01

    ... management objectives as required by statute, GAO internal directive, or formal agreements between GAO and... individual's rights, benefits, and privileges under Federal programs. Factors to be considered in determining... persons to submit written data, views, or arguments to GAO....

  4. Gaos y la religión

    Directory of Open Access Journals (Sweden)

    Silvia Valdés

    2013-11-01

    Full Text Available At first sight, one may be confused when finds that Jose Gaos rejected the possibilty of knowing something about God and at the same time insisted on Its necessity. Nevertheless, a deeper analysis on Gaos's thought about religion shows that this position is consistent with his vitalism.

  5. Gao's Conjecture on Zero-Sum Sequences

    Indian Academy of Sciences (India)

    B Sury; R Thangadurai

    2002-08-01

    In this paper, we shall address three closely-related conjectures due to van Emde Boas, W D Gao and Kemnitz on zero-sum problems on $\\mathbf{Z}_p \\oplus \\mathbf{Z}_p$. We prove a number of results including a proof of the conjecture of Gao for the prime = 7 (Theorem 3.1). The conjecture of Kemnitz is also proved (Propositions 4.6, 4.9, 4.10) for many classes of sequences.

  6. GAO Jian's Theoretical Thoughts in Translation

    Institute of Scientific and Technical Information of China (English)

    区沛仪

    2016-01-01

    As an experienced translator and theorist, GAO Jian has translated numerous English works into Chinese and pub-lished a series of theoretical thoughts concerning the most fundamental problems in translation studies. He has formed a unique style in translation and proposed some theoretical concepts with great expertise. Gao represents the translators'spirit of the time. His theories are highly comprehensive and pragmatic. His discussion of translatability of style, relativity and the Language Characteristics Theory reflect the academic thinking among translators in China, which inspires many young translators and the-orists.

  7. 4 CFR 25.3 - Admission to the GAO building.

    Science.gov (United States)

    2010-01-01

    ... 4 Accounts 1 2010-01-01 2010-01-01 false Admission to the GAO building. 25.3 Section 25.3 Accounts GOVERNMENT ACCOUNTABILITY OFFICE GENERAL PROCEDURES CONDUCT IN THE GOVERNMENT ACCOUNTABILITY OFFICE BUILDING AND ON ITS GROUNDS § 25.3 Admission to the GAO building. A person may be admitted to the GAO Building...

  8. [Gao Yuchun's experience of facial paralysis treatment].

    Science.gov (United States)

    Wang, Yanjun; Cui, Linhua; Yuan, Jun; He, Li; Xie, Zhanqing; Xue, Weihua; Li, Mei; Zhang, Zhenwei; Gao, Yuchun; Kang, Suobin

    2015-05-01

    To introduce professor Gao Yuchun's clinical experience and treating characteristics of facial paralysis treated with acupuncture and moxibustion. Professor Gao pays attention to yangming when he selects acupoints for clinical syndrome, and directs acupoints selection based on syndrome differentiation in different levels of jingjin, meridians and zangfu; he praises opposing needling technique and reinforcing the deficiency and reducing the excess highly; the acupuncture manipulation is gentle,shallow and slow for reducing the healthy side and reinforcing the affected side, and through losing its excess to complement its deficiency; besides, he stresses needle retaining time and distinguishes reinforcing and reducing. Facial paralysis is treated with key factors such as acupoints selecting based on yangming, acupuncture manipulation, needle retaining time, etc. And the spleen and stomach is fine and good at transportation and transformation; the meridians is harmonious; the qi and blood is smooth. The clinical efficacy is enhanced finally.

  9. Gao Ping's Urban Perspective

    Institute of Scientific and Technical Information of China (English)

    YANGYONGLI

    2003-01-01

    GAO Ping's candid artistic expression effectively communicates to art lovers a feeling of tranquility and peace. Her inspiration springs largely from scenery,the urban scenarios of her Cities series imbued with the spiritual. Metaphors implicit in the realist and conceptual images of her paintings—in tacit dialogues between human forms and mystic symbols against an urban backdrop—expand to the full the cityscape concept of her paintings.

  10. Gao Qingmin:Forging a Legend Back to Life

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    SWORD-MAKER Gao Qingmin first dreamt of making swords when standing by his father at the furnace. As a teenager, he was apprenticed to his blacksmith father Gao Xikun, and schooled in stories of master ironsmiths Ou Yezi and Gan Jiang,both famous for forging highquality Tangxi swords.

  11. [Professor GAO Yuchun's experience of acupuncture for headache].

    Science.gov (United States)

    Cui, Linhua; Xing, Xiao; Xue, Weihua; Wang, Yanjun; Xu, Cejun; Xuc, Jun; Gao, Yuchun; Kang, Suobin

    2015-12-01

    As one of the important founders of GAO's acupuncture academic school in YanZhao area, Professor GAO Yuchun 's experience of acupuncture for headache is summarized in this paper. In the opinion of Professor GAO, the treatment of headache should focus on eliminating evil and relieving pain, and the syndrome differentiation should be based on meridian differentiation, especially on three yang meridians of foot as well as liver meridian and kidney meridian. In the acupoint prescription, attention should be placed on strengthening the spleen and stomach. The midnight-midday ebb flow acupuncture is advocated. The combination between acupuncture order and movement of qi is emphasized. In the manipulation, the role of pressing hand, the stimulation during reinforcing and reducing methods, and needle-retention time are important. The breathing reinforcing and reducing method of acupuncture are also advocated.

  12. [Effective acupoints for bulbar paralysis by professor GAO Weibin].

    Science.gov (United States)

    Kang, Lianru; Zheng, Shuang

    2016-04-01

    Professor GAO Weibin academically advocates, based on basic theory of TCM and theories of different schools, modern science technology should be used for the methods and principles of acupuncture and Chinese medicine for neuropathy, so as to explore and summarize the rules, characteristics and advantages of TCM for nervous system disease, especially bulbar paralysis. During the treatment of bulbar paralysis, professor GAO creatively proposes the effective acupuncture points such as Gongxue, Tunyan-1, Tunyan-2, Fayin, Tiyan and Zhifanliu from the aspects of neuroanatomy, and analyzes their anatomical structure and action mechanism.

  13. The MueLu Tutorial

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Jonathan Joseph [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Wiesner, Tobias A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Prokopenko, Andrey [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gee, Michael [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-10-01

    The MueLu tutorial is written as a hands-on tutorial for MueLu, the next generation multigrid framework in Trilinos. It covers the whole spectrum from absolute beginners’ topics to expert level. Since the focus of this tutorial is on practical and technical aspects of multigrid methods in general and MueLu in particular, the reader is expected to have a basic understanding of multigrid methods and its general underlying concepts. Please refer to multigrid textbooks (e.g. [1]) for the theoretical background.

  14. WaiGao Qiao: taking supercritical technology to new heights

    Energy Technology Data Exchange (ETDEWEB)

    Kessel, W.; Weiss, G.; Kawa, P. [Alstom, Stuttgart (Germany)

    2006-06-15

    In their first two years of commercial life the two supercritical boilers of Wai Gao Qiao Phase II, at 900 MWe each the largest operating coal fired units in China and the largest tangentially fired bituminous coal fired boilers in the world have performed reliably and efficiently. 11 figs., 1 tab.

  15. GAOS: Spatial optimisation of crop and nature within agricultural fields

    NARCIS (Netherlands)

    Bruin, de S.; Janssen, H.; Klompe, A.; Lerink, P.; Vanmeulebrouk, B.

    2010-01-01

    This paper proposes and demonstrates a spatial optimiser that allocates areas of inefficient machine manoeuvring to field margins thus improving the use of available space and supporting map-based Controlled Traffic Farming. A prototype web service (GAOS) allows farmers to optimise tracks within the

  16. 48 CFR 833.104 - Protests to GAO.

    Science.gov (United States)

    2010-10-01

    ... REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Protests 833.104 Protests to GAO. (a) General procedures. (1..., or the Director, Office Construction and Facilities Management, as appropriate, within 5 workdays... Director, Office of Construction and Facilities Management, as appropriate, approves the findings of the...

  17. Level structure of 159Lu

    Institute of Scientific and Technical Information of China (English)

    SHENG Hai-Qing; ZHAI Jian; LI Xian-Feng; MA Ying-Jun; ZHAO Yan-Xin; WANG Ya-Kun; ZHAO Lei; ZHU Li-Hua; WU Xiao-Guang; HE Chuang-Ye; LIU Yin; HAO Xin; LI Xue-Qin

    2009-01-01

    The high-spin states of 159Lu were populated by fusion-evaporation reaction 144Sm (19F, 4n) with beam energy 106 MeV. A new level scheme was established, which consists of the yrast band with negative parity, the octupole vibration band based on the states and quasipartical band with positive parity. The high spin states of 159Lu were discussed by systemic characteristics.

  18. Solution of Contact Problems for Nonlinear Gao Beam and Obstacle

    Directory of Open Access Journals (Sweden)

    J. Machalová

    2015-01-01

    Full Text Available Contact problem for a large deformed beam with an elastic obstacle is formulated, analyzed, and numerically solved. The beam model is governed by a nonlinear fourth-order differential equation developed by Gao, while the obstacle is considered as the elastic foundation of Winkler’s type in some distance under the beam. The problem is static without a friction and modeled either using Signorini conditions or by means of normal compliance contact conditions. The problems are then reformulated as optimal control problems which is useful both for theoretical aspects and for solution methods. Discretization is based on using the mixed finite element method with independent discretization and interpolations for foundation and beam elements. Numerical examples demonstrate usefulness of the presented solution method. Results for the nonlinear Gao beam are compared with results for the classical Euler-Bernoulli beam model.

  19. GAO: Government Accountability Office and General Accounting Office

    Science.gov (United States)

    2007-06-22

    years, these have included the power to bring suit to require the release of impounded funds (2 U.S.C. 687); a duty to impose civil penalties under the...offices; imposed a 5-year hiring freeze; eliminated performance rewards; curtailed technology investments; and reduced travel, training, supplies, and...Washington: GPO, 1979), p. 2. 18 Ibid. 19 An article on changes at GAO at the time is by Susannah Zak Figura , “The Human Touch,” Government

  20. LU Peizhang receives Golay Award

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ Prof. LU Peizhang, an analytical chemist with the CAS Dalian Institute of Chemical Physics, received the prestigious Golay Award at the 30th International Symposium on Capillary Chromatography opened on 5 June in Dalian, a port city in northeast China's Liaoning Province.

  1. 2015年鲁迅研究述评%The Review on Lu Xun’s Research in 2015

    Institute of Scientific and Technical Information of China (English)

    崔云伟

    2016-01-01

    2015年鲁迅研究依然保持了持续发展的势头,在平淡从容中出现了诸多热点和亮点。宋剑华、勒新来、刘春勇、高旭东等皆对鲁迅小说发表了极为精彩的看法。汪卫东、彭小燕、朱崇科的《野草》研究均可称得上别具一格。张克、刘春勇的鲁迅杂文研究,文贵良、路杨的鲁迅整体研究皆有其新颖独到之处。思想研究主要集中为十个专题:鲁迅与五四、鲁迅的精神信仰、鲁迅的精神特质、鲁迅的当代性、鲁迅与革命、鲁迅与政治、鲁迅与中国传统文化、鲁迅与外国文化、鲁迅与东亚、鲁迅与自由主义等,郜元宝、汪卫东、谭桂林、杨义、李春林、王得后、李玮、孙郁、赵京华、张松等的文章皆堪称优异之作。李冬木、潘世圣、张钊贻的史料研究,傅承洲、刘克敌、刘东方的鲁迅与学术研究,皆能予人以新的感受和认识。%In 2015, the research on Lu Xun remained continuous. There were many remarkable works among these researches. Great views on Lu Xun’s novels were made by Song Jianhua, Jin Xinlai and Liu Chunyong, etc. The study on Wild Weeds made by Wang Weidong, Peng Xiaoyan and Zhu Chongke was unique. Zhang ke and Liu Chunyong’s study on Lu Xun’s essay and Wen Guil-iang, Lu Yang’s holistic study on Lu Xun have original ideas. Study on thoughts mainly focused on the following ten aspects: Lu Xun and May Fourth, Lu Xun’s spiritual belief, Lu Xun’s spiritual characteristic, Lu Xun’s contemporariness, Lu Xun and Revolution, Lu Xun and Politics, Lu Xun and Chinese Traditional Culture, Lu Xun and Foreign Culture, Lu Xun and East Asia, Lu Xun and Liberal-ism. The articles written by Gao Yuanbao, Wang Weidong, Tan Guilin, Yang Yi, Li Chunlin, Wang Dehou, Li Wei, Sun Yu, Zhao Jinghua and Zhang Song, etc, were considered to be outstanding. Both the study on historical material made by Li Dongmu, Pan Shish-eng and Zhang Zhaoyi and the

  2. Ying La or Ying Lu?

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    <正>As a new star in politics of Thailand,Yingluck Shinawatra has never thought that a dispute about her Chinese name is occurring in a Chinese speaking country--China,when people come to focus on her familY background,new deal,and her tomorrow.Media reporters and editors are wavering between"Ying La"and"Ying Lu".

  3. 4 CFR 81.5 - Records originating outside GAO, records of interviews, or records involving work in progress.

    Science.gov (United States)

    2010-01-01

    ... GAO, records of interviews, or records involving work in progress. (a) It is the policy of GAO not to... a record of interview. (c) In order to avoid disruption of work in progress, and in the interests of... 4 Accounts 1 2010-01-01 2010-01-01 false Records originating outside GAO, records of interviews...

  4. Hexagonal LuMnO3 revisited

    NARCIS (Netherlands)

    Aken, Bas B. van; Meetsma, Auke; Palstra, Thomas T.M.

    2001-01-01

    The crystal structure of hexagonal LuMnO3 at room temperature is isomorphous with YMnO3 and deviates in important details from early work. Mn is near the centre of its oxygen coordination environment. On the threefold axes, the apical O-Lu bonds have alternating long and short bond lengths, leading

  5. [Professor GAO Yuchun's experience on "sequential acupuncture leads to smooth movement of qi"].

    Science.gov (United States)

    Wang, Yanjun; Xing, Xiao; Cui, Linhua

    2016-01-01

    Professor GAO Yuchun is considered as the key successor of GAO's academic school of acupuncture and moxibustion in Yanzhao region. Professor GAO's clinical experience of, "sequential acupuncture" is introduced in details in this article. In Professor GAO's opinions, appropriate acupuncture sequence is the key to satisfactory clinical effects during treatment. Based on different acupoints, sequential acupuncture can achieve the aim of qi following needles and needles leading qi; based on different symptoms, sequential acupuncture can regulate qi movement; based on different body positions, sequential acupuncture can harmonize qi-blood and reinforcing deficiency and reducing excess. In all, according to the differences of disease condition and constitution, based on the accurate acupoint selection and appropriate manipulation, it is essential to capture the nature of diseases and make the order of acupuncture, which can achieve the aim of regulating qi movement and reinforcing deficiency and reducing excess.

  6. Highlights of GAO’s Corporate Governance, Transparency and Accountability Forum

    Science.gov (United States)

    2002-03-01

    United States General Accounting Office GAO By the Comptroller General of the United States March 2002 HIGHLIGHTS OF GAO’S CORPORATE GOVERNANCE , TRANSPARENCY...to) - Title and Subtitle HIGHLIGHTS OF GAO S CORPORATE GOVERNANCE , TRANSPARENCY AND ACCOUNTABILITY FORUMs Contract Number Grant Number Program...Subject: Highlights of GAO’s Corporate Governance , Transparency, and Accountability Forum The recent sudden and largely unexpected bankruptcy of one

  7. The influence of senior secondary school teachers on students’ achievement in Gao-Kao

    Directory of Open Access Journals (Sweden)

    Samson Maekele Tsegay

    2015-04-01

    Full Text Available This study examines the role and influence of teachers on the achievement of students in Gao-Kao (Chinese College Entrance Examination in China. Every year, millions of Chinese students participate in Gao-Kao. However, not all the students join higher education institutions due to limited opportunity for higher education. Through semi-structured interview with undergraduate students, this study examines the role and influence of teachers on the achievement of students in Gao-Kao in China. In order to understand the participants’ experiences and realities, the notion of Gao-Kao and the ways on how teachers influence students’ achievement must be understood. Gao-Kao has been an important milestone for Chinese students. Since its resumption in 1977, the exam has been the dominant means of admission in Chinese higher education institutions. As part and parcel of the teaching-learning process, teachers significantly contribute to students’ achievement in Gao-Kao through engaging students to the teaching-learning process, guidance and evaluation, role modeling as well as motivation. The study will be informative to educators interested in students’ academic achievement in national and other similar types of examinations.

  8. THE LU ISOTOPIC COMPOSITION OF ACHONDRITES: CLOSING THE CASE FOR ACCELERATED DECAY OF {sup 176}LU

    Energy Technology Data Exchange (ETDEWEB)

    Wimpenny, Josh; Yin, Qing-zhu [Department of Earth and Planetary Sciences, University of California, One Shields Avenue, Davis, CA 95616 (United States); Amelin, Yuri, E-mail: jbwimpenny@ucdavis.edu [Research School of Earth Sciences, The Australian National University, Canberra, ACT 0200 (Australia)

    2015-10-10

    Studies of Lu–Hf isotope systematics in meteorites have produced apparent “ages” that are older than Pb–Pb ages and older than the estimated age of our solar system. One proposed explanation for this discrepancy is that irradiation by cosmic rays caused excitation of {sup 176}Lu to its short-lived isomer that then underwent rapid decay to {sup 176}Hf. This explanation can account for apparent excesses in {sup 176}Hf that correlate with Lu/Hf ratio. Mass balance requires that samples with measurable excess in {sup 176}Hf should also have measurable deficiencies in {sup 176}Lu on the order of 1‰–3‰. To unambiguously test the accelerated decay hypothesis, we have measured the {sup 176}Lu/{sup 175}Lu ratio in terrestrial materials and achondrites to search for evidence of depletion in {sup 176}Lu. To a precision of 0.1‰ terrestrial standards, cumulate and basaltic eucrites and angrites all have the same {sup 176}Lu/{sup 175}Lu ratio. Barring a subsequent mass-dependent fractionation event, these results suggest that the apparent excesses in {sup 176}Hf are not caused by accelerated decay of {sup 176}Lu, and so another hypothesis is required to explain apparently old Lu–Hf ages.

  9. lu sildistamine / Erkki Bahovski

    Index Scriptorium Estoniae

    Bahovski, Erkki, 1970-

    2007-01-01

    President Toomas Hendrik Ilvese üleskutsest moodustada Mälu Instituut Eesti lähimineviku uurimiseks. Autori arvates on Vene propaganda taustal raske uurida ajalugu sine ira et studio ("ilma viha ja eelarvamusteta"), nagu soovitas president

  10. Hybrid synchronization of hyperchaotic Lu system

    Indian Academy of Sciences (India)

    K Sebastian Sudheer; M Sabir

    2009-10-01

    In this paper, we study the hybrid synchronization between two identical hyperchaotic Lu systems. Hybrid synchronization of hyperchaotic Lu system is achieved through synchronization of two pairs of states and anti-synchronization of the other two pairs of states. Active controls are designed to achieve hybrid synchronization between drive and response systems using the sum and difference of relevant variables of the chaotic systems. Numerical simulations are presented to evaluate the analysis and effectiveness of the controllers.

  11. Hydrothermal route to Eu doped LuO(OH) and Lu2O3 nanorods

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    A facile method was developed to synthesize Eu doped LuO(OH) nanorods through hydrothermal processing and Lu2O3 nanorods by subsequent calcining.The microstructural morphologies of the Lu-based nanostructures could be controlled by simply varying the concentration of NaOH in hydrothermal processing as mineralizer.TEM observation revealed that the obtained LuO(OH) nanorods after hydrothermal processing had a uniform diameter of 10-25 nm and a length around 100 nm.After heat treatment at 600-700°C for 2 h,the high length/diameter ratio was sustained in the obtained Lu2O3 nanorods with different sizes depending on the calcining temperatures.

  12. The political Thought of José Gaos. The Criticism of Totalitarianism

    Directory of Open Access Journals (Sweden)

    Antolín Sánchez Cuervo

    2017-01-01

    Full Text Available Jose Gaos's diverse writings are reviewed, many of them scantily known and still unpublished, related to the area of the politics in the wide sense of the term. It was the case of some reflections motivated by the global protagonism of the war, the totalitarianism and the technocracy in the current manners of life, including those that are typical of the democratic western companies. In line with this protagonism, Gaos raised a genealogical review of the secularizing process of modern rationality, which will connect with some of his big worries, such as the possibility of the philosophy itself and the possibility of the Hispanic philosophy especially.

  13. Preparation and Preliminary Evaluation of 177Lu-EDTMP

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>The study on 177Lu labeled radiopharmaceuticals for cancer therapy is fast emerging as an important part of nuclear medicine. 177Lu-EDTMP is possible to be an effective radiopharmaceutical for pain

  14. A Probe into Similarities between Gulian and GAO Jia-lin%于连与高加林相似性探究

    Institute of Scientific and Technical Information of China (English)

    曾丽

    2015-01-01

    The two novels,Stendhal’The Red and the Black and LU Yao’s Life ,are the two mirrors of their own time.Though there exist some differences in their backgrounds,living places and cultures between the protagonists of the two novels Gulian and GAO Jia-lin,they were in the transition of old and new times,they have shown great similarities between their struggling courses and tragic fates.%司汤达《红与黑》和路遥《人生》,是他们各自所处时代社会的一面镜子。两部作品中的主人公于连和高加林虽然存在着出身、生存地域、文化背景的不同,但他们都处于新旧交替时代,其奋斗历程、悲剧命运有许多相似之处。

  15. Spectral properties of hydrothermally-grown Nd:LuAG, Yb:LuAG, and Yb:Lu{sub 2}O{sub 3} laser materials

    Energy Technology Data Exchange (ETDEWEB)

    Brown, David C., E-mail: DBrown@snakecreeklasers.com [Snake Creek Lasers LLC, Friendsville, PA 18818 (United States); McMillen, Colin D.; Moore, Cheryl; Kolis, Joseph W. [Department of Chemistry and Center for Optical Materials Science and Engineering Technologies, Clemson University, Clemson, SC 29634-0973 (United States); Envid, Victoria [Snake Creek Lasers LLC, Friendsville, PA 18818 (United States)

    2014-04-15

    We have investigated the hydrothermal growth of, and spectrally characterized, the lutetium based laser materials Nd:LuAG, Yb:LuAG, and Yb:Lu{sub 2}O{sub 3}. Absorption cross-section data are presented for Nd:LuAG at 83, 175, and 295 K. Absorption cross-section data was also obtained for Yb:LuAG at 83, 175, and 295 K; the 295 K data was used to generate emission cross-sections using the method of reciprocity. For Yb:Lu{sub 2}O{sub 3}, we present absorption cross-sections at 295 K as well as emission cross-sections derived using reciprocity. -- Highlights: • We present spectral properties for hydrothermally-grown laser crystals. • Absorption cross-section data are presented for Nd:LuAG and Yb:LuAG at 83, 175, and 295 K. • Emission cross-sections are presented for Yb:LuAG at 295 K derived by reciprocity. • We present absorption cross-sections at 295 K as well as emission cross-sections derived using reciprocity for the laser material Yb:Lu{sub 2}O{sub 3}.

  16. Writers and Their Maps: The Construction of a GAO Report on Sexual Harassment.

    Science.gov (United States)

    Cook, Kelli Cargile

    2000-01-01

    Examines a 1994 General Accounting Office (GAO) report on sexual harassment at U.S. service academies to determine how power structures affected the report writers' rhetorical choices. Identifies what is valued and devalued in the report's contents. Describes Congress's reaction to the report and speculates on the report's impact on public…

  17. lu, kallis vara / Peeter Maimik

    Index Scriptorium Estoniae

    Maimik, Peeter, 1944-2010

    2009-01-01

    Poola ohvitseride mõrvamisest NKVD poolt 1940. aastal Katõnis, Andrzej Wajda selleteemalisest filmist "Katõn" ja ajaloolise mälu säilitamise olulisusest. Inimsusevastaste kuritegude uurimise rahvusvahelise komisjoni uurimistööst, mis käsitleb Saksa ja Nõukogude okupatsioone Eestis

  18. LU's Combined Acupuncture Techniques for Diarrhea

    Institute of Scientific and Technical Information of China (English)

    LI Yan-fang; CHEN Chen; NI Zhi-zhen; ZHONG Chen; XIAO Yuan-chun

    2003-01-01

    @@ Diarrhea refers to frequent discharge of loose, even watery stool. In clinic, we used the famous acupuncturist LU Shou-yan's combined acupuncture techniques of along-against, lifting-thrusting and quickslow reinforcing and reducing to treat diarrhea. Now it is reported as follows.

  19. LU factorization for accelerator-based systems

    KAUST Repository

    Agullo, Emmanuel

    2011-12-01

    Multicore architectures enhanced with multiple GPUs are likely to become mainstream High Performance Computing (HPC) platforms in a near future. In this paper, we present the design and implementation of an LU factorization using tile algorithm that can fully exploit the potential of such platforms in spite of their complexity. We use a methodology derived from previous work on Cholesky and QR factorizations. Our contributions essentially consist of providing new CPU/GPU hybrid LU kernels, studying the impact on performance of the looking variants as well as the storage layout in presence of pivoting, tuning the kernels for two different machines composed of multiple recent NVIDIA Tesla S1070 (four GPUs total) and Fermi-based S2050 GPUs (three GPUs total), respectively. The hybrid tile LU asymptotically achieves 1 Tflop/s in single precision on both hardwares. The performance in double precision arithmetic reaches 500 Gflop/s on the Fermi-based system, twice faster than the old GPU generation of Tesla S1070. We also discuss the impact of the number of tiles on the numerical stability. We show that the numerical results of the tile LU factorization will be accurate enough for most applications as long as the computations are performed in double precision arithmetic. © 2011 IEEE.

  20. Properties of LuAP: CE scintillator containing intentional impurities

    CERN Document Server

    Petrosyan, A G; Ovanesyan, K; Lecoq, Paul; Auffray, Etiennette; Trummer, Julia; Kronberger, Matthias; Pédrini, C; Dujardin, C; Anfre, P

    2007-01-01

    Single crystals of LuAP:Ce and LuYAP(Lu*70%):Ce co-doped with tetravalent (Hf and Zr) and pentavalent (Ta) ions were grown from melts by the Bridgman process. Underlying absorption, slope of the optical edge and transmission in the range of emission were compared to those of LuAP:Ce crystals. Absorption coefficients at 260 nm less than 2 cm−1 have been recorded in LuAP:Ce crystals containing tetravalent ions that are lower than the corresponding figures (5–6 cm−1) measured in undoped LuAP. At high concentrations of added impurities, despite of suppression of the parasitic underlying absorption below 300 nm, the slope of the optical edge and transmission in the range of emission are seriously damaged. Scintillation parameters of crystals with added impurities are compared to those of LuAP:Ce.

  1. Numerical study of compression corner flowfield using Gao-Yong turbulence model%Numerical study of compression corner flowfield using Gao-Yong turbulence model

    Institute of Scientific and Technical Information of China (English)

    GAO Ge; ZHANG Chang-xian; YAN Wen-hui; WANG Yong

    2012-01-01

    A numerical simulation of shock wave turbulent boundary layer interaction induced by a 24° compression corner based on Gao-Yong compressible turbulence model was presented.The convection terms and the diffusion terms were calculated using the second-order AUSM(advection upstream splitting method) scheme and the second-order central difference scheme,respectively.The Runge-Kutta time marching method was employed to solve the governing equations for steady state solutions.Significant flow separation-region which indicates highly non-isotropic turbulence structure has been found in the present work due to intensity interaction under the 24° compression corner.Comparisons between the calculated results and experimental data have been carried out,including surface pressure distribution,boundary-layer static pressure profiles and mean velocity profiles.The numerical results agree well with the experimental values,which indicate Gao-Yong compressible turbulence model is suitable for the prediction of shock wave turbulent boundary layer interaction in two-dimensional compression corner flows.

  2. Production of {sup 177}Lu at the new research reactor FRM-II: Irradiation yield of {sup 176}Lu(n,{gamma}){sup 177}Lu

    Energy Technology Data Exchange (ETDEWEB)

    Dvorakova, Z. [Institut fuer Radiochemie der Technischen Universitaet Muenchen, D-85748 Garching (Germany)], E-mail: nov@rad.chemie.tu-muenchen.de; Henkelmann, R.; Lin, X.; Tuerler, A. [Institut fuer Radiochemie der Technischen Universitaet Muenchen, D-85748 Garching (Germany); Gerstenberg, H. [ZWE FRM-II der Technischen, Universitaet Muenchen, D-85748 Garching (Germany)

    2008-02-15

    Due to its physical and chemical characteristics, {sup 177}Lu is a very attractive radionuclide for use in nuclear medicine. This paper introduces a method for a precise calculation of the irradiation yield of {sup 177}Lu produced by neutron activation of {sup 176}Lu in a nuclear reactor. The calculation is based on the Westcott convention which requires the knowledge of the neutron flux parameters. In this work, the neutron flux parameters of the new research reactor FRM-II (Garching, Germany) were determined and the stability of thermal neutron flux and thermal neutron flux temperature was monitored. The comparison of theoretically calculated and experimentally determined yield for {sup 176}Lu(n,{gamma}){sup 177}Lu reaction is presented.

  3. A new polymorph of Lu(PO33

    Directory of Open Access Journals (Sweden)

    Anis Bejaoui

    2008-08-01

    Full Text Available A new polymorph of lutetium polyphosphate, Lu(PO33, was found to be isotypic with the trigonal form of Yb(PO33. Two of the three Lu atoms occupy special positions (Wyckoff positions 3a and 3b, site symmetry overline{3}. The atomic arrangement consists of infinite helical polyphosphate chains running along the c axis, with a repeat period of 12 PO4 tetrahedra, joined with LuO6 octahedra.

  4. Ionic liquid-based hydrothermal synthesis of Lu2O3 and Lu2O3:Eu3+ microcrysals

    Science.gov (United States)

    Li, Yinyan; Xu, Shiqing

    2016-09-01

    Uniform and well-defined Lu2O3 and Lu2O3:Eu3+ microarchitectures have been successfully synthesized via a green and facile ionic liquid-based hydrothermal method followed by a subsequent calcination process. Novel 3D micro-rodbundles and 1D microrods of Lu2O3 and Lu2O3:Eu3+ were controllably obtained through this method. X-ray powder diffraction, scanning electron microscopy, transmission electron microscopy and photoluminescence spectra were used to characterize the micromaterials. The proposed formation mechanisms have been investigated on the basis of a series of SEM studies of the products obtained at different hydrothermal durations. The results indicated that hydrothermal temperature and the ionic liquid-tetrabutylammonium hydroxide were two key factors for the formation as well as the morphology control of the Lu2O3 and Lu2O3:Eu3+ microarchitectures.

  5. SuperLU users' guide

    Energy Technology Data Exchange (ETDEWEB)

    Demmel, James W.; Gilbert, John R.; Li, Xiaoye S.

    1999-11-01

    This document describes a collection of three related ANSI C subroutine libraries for solving sparse linear systems of equations AX = B: Here A is a square, nonsingular, n x n sparse matrix, and X and B are dense n x nrhs matrices, where nrhs is the number of right-hand sides and solution vectors. Matrix A need not be symmetric or definite; indeed, SuperLU is particularly appropriate for matrices with very unsymmetric structure. All three libraries use variations of Gaussian elimination optimized to take advantage both of sparsity and the computer architecture, in particular memory hierarchies (caches) and parallelism.

  6. Prof. Lu Yongxiang Elected IAC Co-Chair

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ CAS President Lu Yongxiang was elected co-chair of the InterAcademy Council (IAC) at the Fifth Annual Meeting of the IAC Board held from January 31 to February 2 in Amsterdam, the Netherlands. President Lu is to succeed Prof. Goverdhan Mehta,former President of the Indian National Science Academy, to represent those from the developing world in the organization.

  7. Neutron capture reactions on Lu isotopes at DANCE

    Directory of Open Access Journals (Sweden)

    Wouters J.M.

    2010-03-01

    Full Text Available The DANCE (Detector for Advanced Neutron Capture Experiments array located at the Los Alamos national laboratory has been used to obtain the neutron capture cross sections for the 175Lu and 176Lu isotopes with neutron energies from thermal up to 100 keV. Both isotopes are of current interest for the nucleosynthesis s-process in astrophysics and for applications as in reactor physics or in nuclear medicine. Three targets were used to perform these measurements. One was natLu foil and the other two were isotope-enriched targets of 175Lu and 176Lu. The cross sections are obtained for now through a precise neutron flux determination and a normalization at the thermal neutron cross section value. A comparison with the recent experimental data and the evaluated data of ENDF/B-VII.0 will be presented. In addition, resonances parameters and spin assignments for some resonances will be featured.

  8. Neutron Capture Reactions on lu Isotopes at Dance

    Science.gov (United States)

    Roig, O.; Meot, V.; Daugas, J.-M.; Morel, P.; Jandel, M.; Vieira, D. J.; Bond, E. M.; Bredeweg, T. A.; Couture, A. J.; Haight, R. C.; Keksis, A. L.; Rundberg, R. S.; Ullmann, J. L.; Wouters, J. M.

    2013-03-01

    The DANCE1 (Detector for Advanced Neutron Capture Experiments) array at LANSCE spallation neutron source in Los Alamos has been used to obtain the neutron radiative capture cross sections for 175Lu and 176Lu with neutron energies from thermal up to 100 keV. Both isotopes are of current interest for the nucleosynthesis s-process.2,3 Three targets were used to perform these measurements. One was natural Lu foil of 31 mg/cm2 and the other two were isotope-enriched targets of 175Lu and 176Lu. Firstly, the cross sections were obtained by normalizing yield to a well-known cross section at the thermal neutron energy. Now, we want to obtain absolute cross sections of radiative capture through a precise neutron flux determination, an accurate target mass measurement and an efficiency determination of the DANCE array.

  9. LuAG:Pr, LuAG:La, and LuAP:Ce thin film scintillators for visualisation of x-ray images

    Science.gov (United States)

    Zorenko, Yuriy; Gorbenko, Vitaliy; Voznyak, Taras; Martin, Thierry; Douissard, Paul-Antoine; Mares, Jiri A.; Nikl, Martin

    2009-05-01

    The work is dedicated to investigation of the luminescent properties of UV-emitting single crystalline films (SCF) based on the Lu3Al5O12:La and Lu3Al5O12:Pr garnet and LuAlO3:Ce perovskite compounds grown by liquid phase epitaxy method from the PbO-B2O3 flux onto Y3Al5O12 and YAlO3 substrates, respectively, for testing as scintillation screens in high-resolution microimaging detectors used in applications with synchrotrons radiation. The first image with a spatial resolution of about 1.5 μm of X-ray excited resolution target was obtained using only the UV part of the light of the LuAG:La SCF scintillators. The possible ways for improvement of figure-of-merit of UV emitting SCF scintillators and increase of spatial resolution of the detector are discussed.

  10. 论高似孙的考证学成就%On Gao Sisun's Research Achievements

    Institute of Scientific and Technical Information of China (English)

    毛阔龙

    2014-01-01

    《纬略》征引广博,注重考证,对文辞、名物、年代、地理、风俗、文物、制度、文献等方面多有考证。论文以《纬略》为主对高似孙的考评学成就进行了总结。%"Wei Lue"quoted informed, focusing on research on aspects of diction, name objects, age, geography, customs, cultural, institutional, and many have research literature. This thesis summarized Gao Siusn's evaluation achievements based on"Wei Lue".

  11. Comment on breakdown of Bohr's Correspondence Principle by Bo Gao, In

    CERN Document Server

    Tannous, C

    2001-01-01

    Gao applied LeRoy and Bernstein semi-classical analysis for the energy levels in a potential of the form -C/r^n to sequences of scaled energy differences progressing towards low lying states and found a better agreement with the semi-classical prediction. We checked that for the energy levels obtained by Stwalley et al. with the same potential, the agreement with the semi-classical approximation is better for higher vibrational quantum numbers in agreement with Bohr's correspondence principle.

  12. LUPOD: Collocation in POD via LU decomposition

    Science.gov (United States)

    Rapún, M.-L.; Terragni, F.; Vega, J. M.

    2017-04-01

    A collocation method is developed for the (truncated) POD of a set of snapshots. In other words, POD computations are performed using only a set of collocation points, whose number is comparable to the number of retained modes, in a similar fashion as in collocation spectral methods. Intending to rely on simple ideas which, moreover, are consistent with the essence of POD, collocation points are computed via the LU decomposition with pivoting of the snapshot matrix. The new method is illustrated in simple applications in which POD is used as a data-processing method. The performance of the method is tested in the computationally efficient construction of reduced order models based on POD plus Galerkin projection for the complex Ginzburg-Landau equation in one and two space dimensions.

  13. Ternary compounds and isothermal section in Lu-Fe-Ga ternary system at 773 K

    Science.gov (United States)

    Liu, Fusheng; Ao, Weiqin; Pan, Laicai; Wang, Qibao; Yan, Jialing; Li, Junqin

    2013-06-01

    The isothermal section of the Lu-Fe-Ga ternary system at 773 K was investigated and constructed based on X-ray powder diffraction analysis. Thirteen binary compounds, Lu2Fe17, Lu6Fe23, LuFe2, LuGa3, LuGa2, Lu3Ga5, LuGa, Lu3Ga2, Lu5Ga3, Fe3Ga, Fe6Ga5, Fe3Ga4, FeGa3, nine ternary solid solutions, T1-LuFe2-1.43Ga0-0.57, T2-LuFe1.34-0.92Ga0.68-1.08, T3-LuFe0.52-0.26Ga1.48-1.74, T5-LuFe2.04-1.72Ga0.96-1.28, T6-Lu6Fe23-21.4Ga0-1.6, T7-Lu2Fe17-14.5Ga0-3.5, T8-Lu2Fe12.9-8.1Ga4.1-8.9, T9-LuFe6.8-5.5Ga5.2-6.5, T10-LuFe5.2-4.5Ga6.8-7.5, and two ternary compounds, T4-LuFe2.35Ga0.65 and T11-Lu2FeGa8 have been confirmed. The structures of the five new ternary compounds or solid solution T2, T3, T4, T5 and T8 are determined by Rietveld refinement method.

  14. Vocational Rehabilitation: Better Measures and Monitoring Could Improve the Performance of the VR Program. Report to Congressional Committees. GAO-05-865

    Science.gov (United States)

    Robertson, Robert E.

    2005-01-01

    GAO prepared this report under the Comptroller General's authority as part of an effort to assist policy makers in determining how federal disability programs could more effectively meet the needs of individuals with disabilities and addressed it to each committee of jurisdiction. In this report, GAO assesses: (1) the extent to which state…

  15. Influenza Pandemic: Gaps in Pandemic Planning and Preparedness Need to Be Addressed. Testimony before the Committee on Homeland Security, House of Representatives. GAO-09-909T

    Science.gov (United States)

    Steinhardt, Bernice

    2009-01-01

    As the current H1N1 outbreak underscores, an influenza pandemic remains a real threat to our nation. Over the past 3 years, the US Government Accountability Office (GAO) conducted a body of work, consisting of 12 reports and 4 testimonies, to help the nation better prepare for a possible pandemic. In February 2009, GAO synthesized the results of…

  16. Atomic-layer deposition of Lu2O3

    Science.gov (United States)

    Scarel, G.; Bonera, E.; Wiemer, C.; Tallarida, G.; Spiga, S.; Fanciulli, M.; Fedushkin, I. L.; Schumann, H.; Lebedinskii, Yu.; Zenkevich, A.

    2004-07-01

    Rare earth oxides could represent a valuable alternative to SiO2 in complementary metal-oxide-semiconductor devices. Lu2O3 is proposed because of its predicted thermodynamical stability on silicon and large conduction band offset. We report on the growth by atomic-layer deposition of lutetium oxide films using the dimeric {[C5H4(SiMe3)]2LuCl}2 complex, which has been synthesized for this purpose, and H2O. The films were found to be stoichiometric, with Lu2O3 composition, and amorphous. Annealing in nitrogen at 950°C leads to crystallization in the cubic bixbyite structure. The dielectric constant of the as-grown Lu2O3 layers is 12±1.

  17. Geometric Structures and Field Equations of Dirac-Lu Space

    Institute of Scientific and Technical Information of China (English)

    REN Xin-An; ZHANG Li-You

    2008-01-01

    In this paper, a -invariant Lorentz metric on the Dirac-Lu space is given, and then the geodesic equation is investigated. Finally, we discuss the field equations and find their solutions by the method of separating variables.

  18. LU Yongxiang receives honorary doctoral degree from HKU

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ Together with 1998 Nobel Prize winner in physics Daniel Chee Tsui from Princeton University, CAS President LU Yongxiang was conferred Doctor of Science honoris causa by the University of Hong Kong (HKU) at the congregation held on 24 April.

  19. Catalog of Reports, Decisions and Opinions, Testimonies and Speeches, GAO Documents 113171-113401. Volume 5. Number 10.

    Science.gov (United States)

    1980-10-01

    Annuits tDect- Army Anament Reeeerh and Develop GAO Views on H.R. 7893 ( Tesi - Sion) 113286 en1 Cotwand. Dover. NJ Protest of Procedures IUsed in Arms% mon...Fcderal Insecti- cide , Fungicide, and Rodenticide Act. Abstract-Abeluet: Federal efforts to protect consumers from illegal and potentially harmful

  20. Gulf Coast Hurricanes: Lessons Learned for Protecting and Educating Children. Briefing for Congressional Staff. GAO-06-680R

    Science.gov (United States)

    Government Accountability Office, 2006

    2006-01-01

    In August and September 2005, Hurricanes Katrina and Rita caused devastating damage to states along the Gulf Coast. In the aftermath of the storms, many questions were raised about the status of the thousands of children living in the affected areas. The US Government Accountability Office (GAO) prepared this preliminary information under the…

  1. Luminescence and scintillation properties of BaY2F8 : Ce3+, BaLu2F8 and BaLu2F8 : Ce3+

    NARCIS (Netherlands)

    van't Spijker, JC; Dorenbos, P; van Eijk, CWE; Jacobs, JEM; den Hartog, HW; Korolev, N

    1999-01-01

    Spectroscopic and scintillation properties of BaY2F8 :Ce3+, BaLu2F8 and BaLu2F8 :Ce3+ are presented. For pure BaLu2F8, a luminescence with a decay time of similar to 1 ns is observed under gamma-ray excitation. This luminescence with a light yield of about 200 ph/MeV is attributed to core-valence lu

  2. Exploiting fine-grain parallelism in recursive LU factorization

    KAUST Repository

    Dongarra, Jack

    2012-01-01

    The LU factorization is an important numerical algorithm for solving system of linear equations. This paper proposes a novel approach for computing the LU factorization in parallel on multicore architectures. It improves the overall performance and also achieves the numerical quality of the standard LU factorization with partial pivoting. While the update of the trailing submatrix is computationally intensive and highly parallel, the inherently problematic portion of the LU factorization is the panel factorization due to its memory-bound characteristic and the atomicity of selecting the appropriate pivots. We remedy this in our new approach to LU factorization of (narrow and tall) panel submatrices. We use a parallel fine-grained recursive formulation of the factorization. It is based on conflict-free partitioning of the data and lock-less synchronization mechanisms. Our implementation lets the overall computation naturally flow with limited contention. Our recursive panel factorization provides the necessary performance increase for the inherently problematic portion of the LU factorization of square matrices. A large panel width results in larger Amdahl\\'s fraction as our experiments have revealed which is consistent with related efforts. The performance results of our implementation reveal superlinear speedup and far exceed what can be achieved with equivalent MKL and/or LAPACK routines. © 2012 The authors and IOS Press. All rights reserved.

  3. [An introduction on the editions of Zhang Gao's Yi shuo (Medical Narrations)].

    Science.gov (United States)

    Wang, Xuguang; Lu, Xiang

    2014-11-01

    Zhang Gao's Yi shuo (Medical Narrations) of the Southern Song Dynasty had 2 kinds of editions: domestic editions and foreign editions. The former includes 1 Song edition, 14 Ming editions, 3 Qing editions and 25 editions after the Republic of China. The latter, mainly 2 classes, the Japanese edition and Korean printing type edition. In the Ming Dynasty, the editions of Yi shuo generated 2 branches: inherited edition and supplementary edition. The inherited editions include Gu Dingfang's edition, Zhang Yaode's edition, Wu Mianxue's edition, Wu Zhongheng's edition, Wang Kentang's edition, editions from Si ku quan shu (Imperial Collection of Four), stereotype edition of the 3th year of Xuantong reign (1911) from Shanghai Civilization Bookstore, edition of the 2(nd) year of Manji of Japan etc. The supplemental editions include Zhang Zili's edition, Shen Fan's edition, Fu Feng'ao's edition, transcript of the late Ming Dynasty preserved in the Library of Peking University, and Korean printing type edition etc.

  4. Impact of salinity on the anaerobic metabolism of phosphate-accumulating organisms (PAO) and glycogen-accumulating organisms (GAO).

    Science.gov (United States)

    Welles, L; Lopez-Vazquez, C M; Hooijmans, C M; van Loosdrecht, M C M; Brdjanovic, D

    2014-09-01

    The use of saline water as secondary quality water in urban environments for sanitation is a promising alternative towards mitigating fresh water scarcity. However, this alternative will increase the salinity in the wastewater generated that may affect the biological wastewater treatment processes, such as biological phosphorus removal. In addition to the production of saline wastewater by the direct use of saline water in urban environments, saline wastewater is also generated by some industries. Intrusion of saline water into the sewers is another source of salinity entering the wastewater treatment plant. In this study, the short-term effects of salinity on the anaerobic metabolism of phosphate-accumulating organisms (PAO) and glycogen-accumulating organisms (GAO) were investigated to assess the impact of salinity on enhanced biological phosphorus removal. Hereto, PAO and GAO cultures enriched at a relatively low salinity level (0.02 % W/V) were exposed to salinity concentrations of up to 6 % (as NaCl) in anaerobic batch tests. It was demonstrated that both PAO and GAO are affected by higher salinity levels, with PAO being the more sensitive organisms to the increasing salinity. The maximum acetate uptake rate of PAO decreased by 71 % when the salinity increased from 0 to 1 %, while that of GAO decreased by 41 % for the same salinity increase. Regarding the stoichiometry of PAO, a decrease in the P-release/HAc uptake ratio accompanied with an increase in the glycogen consumption/HAc uptake ratio was observed for PAO when the salinity increased from 0 to 2 % salinity, indicating a metabolic shift from a poly-P-dependent to a glycogen-dependent metabolism. The anaerobic maintenance requirements of PAO and GAO increased as the salinity concentrations risen up to 4 % salinity.

  5. High frequency band crossings in ^168Lu.

    Science.gov (United States)

    Roux, D. G.; Li, Y.; Ma, W. C.; Amro, H.; Thompson, J.; Winger, J.; Hagemann, G.; Herskind, B.; Jensen, D.; Sletten, G.; Wilson, J.; Fallon, P.; Diamond, R.; Goergen, A.; Machiavelli, A.; Ward, D.; Hübel, H.; Domscheit, J.

    2003-10-01

    High spin states in ^168Lu were populated using the ^123Sb(^48Ca,3n) reaction at 203 MeV. The beam was provided by the 88" cyclotron at LBNL, and coincident gamma rays were detected with the Gammasphere spectrometer array. An analysis of the data which had been sorted into three- and four- dimensional histograms confirmed the four previously known (J.H.Ha et al. J. Phys. Soc. Japan 71 (2002) 1663-1671) pairs of signature partner bands and extended them to considerably higher spins (in one case up to a tentative 50 hbar). In addition, a new pair of signature partners, as well as a new doubly decoupled band were found. On the basis of the present data, the configuration of one of the known bands, previously assigned π d_3/2 øtimes ν i_13/2 was reassigned as π d_5/2 øtimes ν i_13/2. High frequency band crossings, beyond the first ν i_13/2 alignment, were observed for the first time. These results will be discussed with reference to Cranking Shell Model calculations.

  6. The covalent bonding interaction in the ferroelectric LuMnO3

    Science.gov (United States)

    Ahn, Suk-Jin; Kim, Jinyoung; Shin, Namsoo; Koo, Yang-Mo

    2011-10-01

    The electron density distributions of paraelectric and ferroelectric LuMnO3 are analyzed using high temperature synchrotron x-ray powder diffraction data with the Rietveld method, the maximum entropy method (MEM), and MEM-based pattern fitting. Bonding electrons due to orbital hybridization are clearly seen in the Lu1-O3 and Lu2-O4 bonds along the c-axis polarization direction. The Lu1-O3 bond was determined to be covalent due to hybridization below the ferroelectric transition temperature, and was identified as the driving force for ferroelectricity in LuMnO3. However, the Lu2-O4 bond shows covalent character in both paraelectric and ferroelectric states. Also, we suggest that the Lu2-O4 covalent bonding is responsible for large spontaneous polarization in LuMnO3, associated with the small radius of the Lu3+ ion.

  7. Adhesive activity of Lu glycoproteins is regulated by interaction with spectrin

    Energy Technology Data Exchange (ETDEWEB)

    An, Xiuli; Gauthier, Emilie; Zhang, Xihui; Guo, Xinhua; Anstee, David; Mohandas, Narla; Anne Chasis, Joel

    2008-03-18

    The Lutheran (Lu) and Lu(v13) blood group glycoproteins function as receptors for extracellular matrix laminins. Lu and Lu(v13) are linked to the erythrocyte cytoskeleton through a direct interaction with spectrin. However, neither the molecular basis of the interaction nor its functional consequences have previously been delineated. In the present study, we defined the binding motifs of Lu and Lu(v13) on spectrin and identified a functional role for this interaction. We found that the cytoplasmic domains of both Lu and Lu(v13) bound to repeat 4 of the spectrin chain. The interaction of full-length spectrin dimer to Lu and Lu(v13) was inhibited by repeat 4 of {alpha}-spectrin. Further, resealing of this repeat peptide into erythrocytes led to weakened Lu-cytoskeleton interaction as demonstrated by increased detergent extractability of Lu. Importantly, disruption of the Lu-spectrin linkage was accompanied by enhanced cell adhesion to laminin. We conclude that the interaction of the Lu cytoplasmic tail with the cytoskeleton regulates its adhesive receptor function.

  8. Superconductivity in Lu{sub 2}SnC

    Energy Technology Data Exchange (ETDEWEB)

    Kuchida, S., E-mail: s-kuchida@phys.aoyama.ac.jp [Department of Physics and Mathematics, Aoyama-Gakuin University, 5-10-1 Fuchinobe, Sagamihara, Kanagawa 252-5258 (Japan); Muranaka, T. [Department of Engineering Science, The University of Electro-Communications, 1-5-1 Chofugaoka, Chofu, Tokyo 182-8585 (Japan); Kawashima, K.; Inoue, K. [Department of Physics and Mathematics, Aoyama-Gakuin University, 5-10-1 Fuchinobe, Sagamihara, Kanagawa 252-5258 (Japan); Yoshikawa, M. [IMRA Material Co. Ltd., 2-1 Asahicho, Kariya, Aichi 448-0032 (Japan); Akimitsu, J. [Department of Physics and Mathematics, Aoyama-Gakuin University, 5-10-1 Fuchinobe, Sagamihara, Kanagawa 252-5258 (Japan)

    2013-11-15

    Highlights: •We discovered the superconductivity in Lu{sub 2}SnC. •The superconducting transition temperature is confirmed at around 5.2 K. •The M–H curve at 1.8 K shows that Lu{sub 2}SnC is categorized to be a conventional type-II superconductor. -- Abstract: We discovered the superconductivity in Lu{sub 2}SnC with the T{sub c} of 5.2 K. Lu{sub 2}SnC crystallizes in a hexagonal structure (Cr{sub 2}AlC-type) with the space group of P6{sub 3}/mmc. We measured the physical properties of Lu{sub 2}SnC in the superconducting state as functions of temperature and magnetic field. The M–H curve shows the typical type-II superconducting behavior. Superconducting parameters H{sub c1}(0), H{sub c2}(0), λ(0), ξ(0) and κ{sub GL} are determined to be about 110 Oe, 4.5 kOe, 250 nm, 27 nm, and 9.2, respectively.

  9. Nd3-xBixFe4GaO12 (x = 2, 2.5 films on glass substrates prepared by MOD method

    Directory of Open Access Journals (Sweden)

    Yoshida T.

    2014-07-01

    Full Text Available We studied Nd3-XBiXFe4GaO12 films to obtain perpendicular magnetic anisotropy as well as large Faraday effect. NdBi2Fe4GaO12 (Bi2:NIGG and Nd0.5Bi2.5Fe4GaO12 (Bi2.5:NIGG films were obtained on Nd2BiFe4GaO12 (Bi1:NIGG layer prepared on glass substrates by metal-organic decomposition (MOD method. Bi2:NIGG and Bi2.5:NIGG films showed large Faraday rotation angles of 7.5 and 10.5 degree/µm, at a wavelength of 520 nm, respectively. Those films have perpendicular magnetic anisotropy with a coercivity of 350 Oe and a saturation magnetic field of 730 Oe.

  10. 运用GAO-YONG湍流模型对扩压器内跨声速流动的数值模拟%Numerical simulation of transonic flows in a diffuser with GAO-YONG turbulence equations

    Institute of Scientific and Technical Information of China (English)

    伏晓艳; 高歌

    2008-01-01

    运用GAO-YONG可压缩湍流方程组,采用同位网格SIMPLE算法,对扩压器跨声速流动中的二维激波/湍流边界层干扰现象进行了数值模拟.将计算得到的流场的时均参数与实验值进行比较,数值模拟结果在激波强度、壁面压力分布以及分离点和再附点位置等方面,与实验值吻合较好,表明GAO-YONG可压缩湍流方程组能够比较准确的模拟较强激波/湍流边界层干扰流动,从而进一步为GAO-YONG湍流模型的正确性及其在可压缩流场模拟方面的适用性提供了佐证.

  11. CVD Lu(2)O(3):Eu coatings For Advanced Scintillators.

    Science.gov (United States)

    Topping, Stephen G; Sarin, V K

    2009-03-01

    Currently Lu(2)O(3):Eu(3+) scintillators can only be fabricated via hot-pressing and pixelization, which is commercially not viable, thus restricting their use. Chemical vapor deposition is being developed as an alternative manufacturing process. Columnar coatings of Lu(2)O(3):Eu(3+) have been achieved using the halide-CO(2)-H(2) system, clearly signifying feasibility of the CVD process. Characterization of the coatings using high resolution scanning electron microscopy (SEM) and x-ray diffraction (XRD) analysis have been used as an aid to optimize process parameters and attain highly oriented and engineered coating structures. These results have clearly demonstrated that this process can be successfully used to tailor sub-micron columnar growth of Lu(2)O(3):Eu(3+), with the potential of ultra high resolution x-ray imaging.

  12. An overview of SuperLU: Algorithms, implementation, and userinterface

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xiaoye S.

    2003-09-30

    We give an overview of the algorithms, design philosophy,and implementation techniques in the software SuperLU, for solving sparseunsymmetric linear systems. In particular, we highlight the differencesbetween the sequential SuperLU (including its multithreaded extension)and parallel SuperLU_DIST. These include the numerical pivoting strategy,the ordering strategy for preserving sparsity, the ordering in which theupdating tasks are performed, the numerical kernel, and theparallelization strategy. Because of the scalability concern, theparallel code is drastically different from the sequential one. Wedescribe the user interfaces ofthe libraries, and illustrate how to usethe libraries most efficiently depending on some matrix characteristics.Finally, we give some examples of how the solver has been used inlarge-scale scientific applications, and the performance.

  13. ^176Lu/^175Lu thermometry for Oklo natural reactors: a new look at old data

    Science.gov (United States)

    Gould, Chris; Sharapov, Eduard

    2012-03-01

    Lutetium thermometry has been used to analyze Oklo natural nuclear reactor zones but leads to widely varying and puzzling predictions for the temperatures TO, which in turn impacts Oklo bounds on the time variation of the fine structure constant α. We revisit results for reactor zone RZ10 in light of new astrophysical measurements of the isomer branching ratio B^g in ^175Lu neutron capture at 5 and 25 keV. We recalculate predictions for TO as a function of B^g using realistic models of the Oklo neutron flux. We find TO= 100 ±30 C using a new value of B^g, in contrast to 350 Oklo reactor data, but a better measurement of B^g with thermal neutrons is needed to confirm the reliability of temperature predictions.

  14. 176Lu/175Lu thermometry for the Oklo natural reactors: A new examination of old data

    Science.gov (United States)

    Gould, C. R.; Sharapov, E. I.

    2012-02-01

    Background: Lutetium thermometry has been used to analyze Oklo natural nuclear reactor zones but leads to widely varying and puzzling predictions for the temperatures TO which in turn impacts bounds on time variation of the fine structure constant α.Purpose: We revisit results for reactor zone RZ10 in light of new measurements of the isomer branching ratio Bg in 175Lu neutron capture at 5 and 25 keV.Method: We recalculate predictions for TO as a function of Bg using realistic models of the Oklo neutron flux.Results: We find TO=100±30 ∘C using a new value of Bg, in contrast to 350Oklo reactor data, but a better measurement of Bg with thermal neutrons is needed to confirm the reliability of temperature predictions.

  15. Fabrication and characterization of spark plasma sintered Ce:LuAG ceramic for scintillation application

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, S. Arun; Senthilselvan, J., E-mail: jsselvan@hotmail.com [Department of Nuclear Physics, University of Madras, Guindy Campus, Chennai–600 025, Tamil Nadu (India)

    2016-05-23

    Rare earth Cerium doped Lutetium Aluminum Garnet (Ce:LuAG) ceramics are widely used as phosphor material in medical imaging and high-energy physics. Due to its technological importance, an attempt has been made to fabricate Ce:LuAG ceramics by using spark plasma sintering (SPS) technique. XRD patterns of SPS sintered Ce:LuAG ceramics reveals a mixed LuAG and CeO{sub 2} (antisite defect) phases. The microstructures of SPS sintered Ce:LuAG ceramics shows limited densification, inappropriate compaction of particles and existence of residual pores, voids between the grain boundaries affects the transparency of Ce:LuAG ceramics. Relative density and hardness of post sintered Ce:LuAG ceramic is also determined. The effect of Ce{sup 3+} doping concentration and sintering temperature on optical luminescence behavior of Ce:LuAG ceramic is presented.

  16. Fabrication and characterization of spark plasma sintered Ce:LuAG ceramic for scintillation application

    Science.gov (United States)

    Kumar, S. Arun; Senthilselvan, J.

    2016-05-01

    Rare earth Cerium doped Lutetium Aluminum Garnet (Ce:LuAG) ceramics are widely used as phosphor material in medical imaging and high-energy physics. Due to its technological importance, an attempt has been made to fabricate Ce:LuAG ceramics by using spark plasma sintering (SPS) technique. XRD patterns of SPS sintered Ce:LuAG ceramics reveals a mixed LuAG and CeO2 (antisite defect) phases. The microstructures of SPS sintered Ce:LuAG ceramics shows limited densification, inappropriate compaction of particles and existence of residual pores, voids between the grain boundaries affects the transparency of Ce:LuAG ceramics. Relative density and hardness of post sintered Ce:LuAG ceramic is also determined. The effect of Ce3+ doping concentration and sintering temperature on optical luminescence behavior of Ce:LuAG ceramic is presented.

  17. Introducing multiple treatment plan-based comparison to investigate the performance of gantry angle optimisation (GAO) in IMRT for head and neck cancer

    DEFF Research Database (Denmark)

    Thor, Maria; Benedek, Hunor; Knöös, Tommy;

    2012-01-01

    The purpose of this study was to evaluate the performance of gantry angle optimisation (GAO) compared to equidistant beam geometry for two inverse treatment planning systems (TPSs) by utilising the information obtained from a range of treatment plans.......The purpose of this study was to evaluate the performance of gantry angle optimisation (GAO) compared to equidistant beam geometry for two inverse treatment planning systems (TPSs) by utilising the information obtained from a range of treatment plans....

  18. The Gao-Guenie impact melt breccia—Sampling a rapidly cooled impact melt dike on an H chondrite asteroid?

    Science.gov (United States)

    Schmieder, Martin; Kring, David A.; Swindle, Timothy D.; Bond, Jade C.; Moore, Carleton B.

    2016-06-01

    The Gao-Guenie H5 chondrite that fell on Burkina Faso (March 1960) has portions that were impact-melted on an H chondrite asteroid at ~300 Ma and, through later impact events in space, sent into an Earth-crossing orbit. This article presents a petrographic and electron microprobe analysis of a representative sample of the Gao-Guenie impact melt breccia consisting of a chondritic clast domain, quenched melt in contact with chondritic clasts, and an igneous-textured impact melt domain. Olivine is predominantly Fo80-82. The clast domain contains low-Ca pyroxene. Impact melt-grown pyroxene is commonly zoned from low-Ca pyroxene in cores to pigeonite and augite in rims. Metal-troilite orbs in the impact melt domain measure up to ~2 mm across. The cores of metal orbs in the impact melt domain contain ~7.9 wt% of Ni and are typically surrounded by taenite and Ni-rich troilite. The metallography of metal-troilite droplets suggest a stage I cooling rate of order 10 °C s-1 for the superheated impact melt. The subsolidus stage II cooling rate for the impact melt breccia could not be determined directly, but was presumably fast. An analogy between the Ni rim gradients in metal of the Gao-Guenie impact melt breccia and the impact-melted H6 chondrite Orvinio suggests similar cooling rates, probably on the order of ~5000-40,000 °C yr-1. A simple model of conductive heat transfer shows that the Gao-Guenie impact melt breccia may have formed in a melt injection dike ~0.5-5 m in width, generated during a sizeable impact event on the H chondrite parent asteroid.

  19. Preparation and Clinical Application of Xiaozhi Gao%消痔膏的研制及临床应用

    Institute of Scientific and Technical Information of China (English)

    马平勃

    2002-01-01

    Objective To establish the preparation and quality control of Xiaozhi Gao and to make a clinical observation on it.Methods Making an attribution analysis by thin layer scanning. Treating 81 cases of piles with the preparation. Result This analysismethod is feasible. The total rate of curation is 97.5%. Conclusion This preparation method is acceptable, with remarkable curativeeffect. It has no ill - effect.

  20. Veterans Affairs Health Care: Addition to GAO’s High Risk List and Actions Needed for Removal

    Science.gov (United States)

    2015-04-29

    appropriate nurse staffing levels and skill mixes needed to support Page 12 GAO-15-580T high-quality patient care in the different care ...facility assesses a provider’s professional competence when a question arises regarding the provider’s ability to provide safe, quality patient care . In...areas, such as clinical competence, research, teaching, patient satisfaction , and administration. Providers who were eligible for performance pay

  1. On the Stark Broadening of Lu III Spectral Lines

    Indian Academy of Sciences (India)

    Zlatko Majlinger; Zoran Simić; Milan S. Dimitrijević

    2015-12-01

    The electron-impact widths for 27 Lu III spectral lines have been calculated by using the modified semiempirical method. Calculations have been also performed with the published relativistic Hartree-Fock oscillator strengths and additionally, with the approximate formula of Cowley.With the obtained results, the influence of Stark broadening on Lu III lines was investigated in the spectra of A-type stars. The obtained data will be included in the STARK-B database, which is part of the Virtual Atomic and Molecular Data Center – VAMDC.

  2. Performance analysis of parallel supernodal sparse LU factorization

    Energy Technology Data Exchange (ETDEWEB)

    Grigori, Laura; Li, Xiaoye S.

    2004-02-05

    We investigate performance characteristics for the LU factorization of large matrices with various sparsity patterns. We consider supernodal right-looking parallel factorization on a bi-dimensional grid of processors, making use of static pivoting. We develop a performance model and we validate it using the implementation in SuperLU-DIST, the real matrices and the IBM Power3 machine at NERSC. We use this model to obtain performance bounds on parallel computers, to perform scalability analysis and to identify performance bottlenecks. We also discuss the role of load balance and data distribution in this approach.

  3. Preparation and Biodistribution Evaluation in Mice of ~(177)Lu-DOTA-TOC

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The study of 177Lu labeled radiopharmaceuticals for cancer therapy is fast emerging as an important part of nuclear medicine. 177Lu-labelling of DOTA derivatized peptide DOTA-TOC (Tyr3-Octreotide) was carried out and biodistribution of 177Lu-DOTA-TOC in normal

  4. Light yield and light loss coefficient of LuAG:Ce and LuAG:Pr under excitation with α- and γ-rays

    Science.gov (United States)

    Sreebunpeng, Krittiya; Chewpraditkul, Weerapong; Nikl, Martin

    2017-06-01

    Light yield and light loss coefficient of Lu3Al5O12:Ce (LuAG:Ce) and Lu3Al5O12:Pr (LuAG:Pr) single crystals grown by the Czochralski method were investigated under excitation with α- and γ-rays. Photoelectron yield and energy resolution were measured using the XP5200B photomultiplier. The dependence of photoelectron yield on sample height was measured under excitation with α- and γ-rays and the light loss coefficient was evaluated. It was found that the light loss coefficient of LuAG:Ce is smaller than that of LuAG:Pr. The ratio of photoelectron yield under excitation with α- and γ-rays (α/γ ratio) was also determined and discussed.

  5. ASASSN-15lu is a Type Ia Supernova

    OpenAIRE

    2015-01-01

    We report spectroscopic classification of ASASSN-15lu (ATel #7698) in SDSS J132112.88+401556.7 (z=0.035037, via NED) through inspection of an optical spectrum (range 370-680 nm, resolution 0.8 nm), obtained with the 2.3-m Bok telescope (+ Boller & Chivens spectrograph) at Kitt Peak on 2015 June 24.2 UT.

  6. ASASSN-15lu is a Type Ia Supernova

    NARCIS (Netherlands)

    Leonard, D.C.; Sheehan, P.; McCarthy, D.; Follette, K.; Moustakas, J.; Cantillo, D.; Cazares-Kelly, A.; Cazares-Kelly, S.; Cendes, Y.; Damm, N.; Donati, A.; Douglas, E.; Ferrell, L.; Fosbinder-Elkins, H.; Fox, C.; Greenberg, M.; Hart, K.; Hensley, H.; Holt, A.; Hooper, E.; Juran, C.; Keane, J.; Key, K.; Korus, L.; Lee, T.; Leidig, K.; Merchak, E.; Nessmann, K.; Pendyala, S.; Pirkl, S.; Reeder, J.; Roos, A.; Rounseville, S.; Ruddy, E.; Schlingman, A.; Schlingman, W.; Schwartzman, E.; Shanmugam, V.; Silver, E.; Stein, A.; Stock, N.; Svoboda, B.; Thomas, B.; Thomas, N.; Thompson-Taylor, K.; Walton, H.

    2015-01-01

    We report spectroscopic classification of ASASSN-15lu (ATel #7698) in SDSS J132112.88+401556.7 (z=0.035037, via NED) through inspection of an optical spectrum (range 370-680 nm, resolution 0.8 nm), obtained with the 2.3-m Bok telescope (+ Boller & Chivens spectrograph) at Kitt Peak on 2015 June 24.2

  7. Resonantly pumped room temperature Ho:LuVO₄ laser.

    Science.gov (United States)

    Yao, B Q; Cui, Z; Duan, X M; Du, Y Q; Han, L; Shen, Y J

    2014-11-01

    Spectroscopic characterization of a Ho:LuVO4 crystal grown by the Czochralski method has been performed, including the absorption and emission spectra. We demonstrate a 2 μm room temperature Ho:LuVO4 laser, resonantly pumped by a 1.94 μm Tm:YAP laser. By use of an output coupler with T=10% transmission, the Ho:LuVO4 laser generated continuous-wave output power of 2.5 W at 2074.18 nm, with a beam quality factor of Mx2=My2=1.3, for a total incident pump power of 19.4 W. The slope efficiency with respect to the pump power was 17.6%, and the optical-to-optical efficiency was 12.9%. Moreover, we obtained a Ho:LuVO4 laser that operated at 2073.77 and 2055.27 nm, by using different output couplers with transmissions of T=15 and 30%.

  8. ASASSN-15lu is a Type Ia Supernova

    NARCIS (Netherlands)

    Leonard, D.C.; Sheehan, P.; McCarthy, D.; Follette, K.; Moustakas, J.; Cantillo, D.; Cazares-Kelly, A.; Cazares-Kelly, S.; Cendes, Y.; Damm, N.; Donati, A.; Douglas, E.; Ferrell, L.; Fosbinder-Elkins, H.; Fox, C.; Greenberg, M.; Hart, K.; Hensley, H.; Holt, A.; Hooper, E.; Juran, C.; Keane, J.; Key, K.; Korus, L.; Lee, T.; Leidig, K.; Merchak, E.; Nessmann, K.; Pendyala, S.; Pirkl, S.; Reeder, J.; Roos, A.; Rounseville, S.; Ruddy, E.; Schlingman, A.; Schlingman, W.; Schwartzman, E.; Shanmugam, V.; Silver, E.; Stein, A.; Stock, N.; Svoboda, B.; Thomas, B.; Thomas, N.; Thompson-Taylor, K.; Walton, H.

    2015-01-01

    We report spectroscopic classification of ASASSN-15lu (ATel #7698) in SDSS J132112.88+401556.7 (z=0.035037, via NED) through inspection of an optical spectrum (range 370-680 nm, resolution 0.8 nm), obtained with the 2.3-m Bok telescope (+ Boller & Chivens spectrograph) at Kitt Peak on 2015 June 24.2

  9. Luminescence and scintillation properties of BaY2F8 : Ce3+, BaLu2F8 and BaLu2F8 : Ce3+

    NARCIS (Netherlands)

    van't Spijker, JC; Dorenbos, P; van Eijk, CWE; Jacobs, JEM; den Hartog, HW; Korolev, N

    1999-01-01

    Spectroscopic and scintillation properties of BaY2F8 :Ce3+, BaLu2F8 and BaLu2F8 :Ce3+ are presented. For pure BaLu2F8, a luminescence with a decay time of similar to 1 ns is observed under gamma-ray excitation. This luminescence with a light yield of about 200 ph/MeV is attributed to core-valence

  10. GAO's Family in Dali Kingdom and Shuimu Mountain's Buddhism%大理国高氏家族和水目山佛教

    Institute of Scientific and Technical Information of China (English)

    聂葛明; 魏玉凡

    2015-01-01

    GAO was the family name of an old prominent family in the history of Dali Kingdom. The power of GAO's family could influence all over the eight prefectures and four counties of Dali Kingdom. GAO's family devoted to developing the local Buddhism, and the head of GAO's family, as the abbot, took charge of the famous temples in Shuimu Mountain—a famous Buddhism mountain in Dali. After the study of archives of GAO's family, as well as the stone inscriptions and other historical documents in Shuimu Mountain, it can be concluded that the source of Shuimu Mountain's Buddhism came from the two branches of Exotoric and Tantric Buddhism of Chongsheng Temple. This paper mainly discusses the special role which GAO's family had played in the inheriting system of the Shuimu Mountain Buddhism, and the importance of Shuimu Mountain's Buddhism to GAO's family.%大理国的高氏家族是当时的名门望族,势力范围遍及大理八府四郡。高氏不仅作为护法公积极发展地方佛教,更作为住持执掌大理佛教名山水目山。通过对高氏家族及水目山碑刻、史料的研究,发现水目山师承崇圣寺并修习显密二法,探讨高氏家族在水目山传承体系中的特殊地位,分析水目山对高氏的重要性。

  11. Wei Gao and the Reopening of the Southern Silk Road in the Tang Dynasty

    Institute of Scientific and Technical Information of China (English)

    Zhao Xinyu

    2016-01-01

    Weigao was one of the famous Jie-dushi ( regional military commissioners ) of the Jiannan Xichuan ( located in today’s southern Si-chuan) in the Tang Dynasty. During the rule of Wei Gao, he successfully defeated the Tubo, and changed the Tang court’s submissiveness in the southwestern region and the fight between the Tang and Tubo along the southern line. He also restored the links between Yunnan and Xichuan including all the way to the Central Plains, and, as a result, the once closed Southern Silk Road was reopened. A further exploration and evaluation of Wei Gao’s actions and his influence on reopening the Southern Silk Road ought to be given. I. Wei Gao’s Alliance with the Nanzhao King-dom and Reopening the Southern Silk Road In 785 A. D. , Wei Gao arrived in Chengdu and was appointed Jiedushi of Jiannan Xichuan. The situation of Jiannan Xichuan at that time was very critical. After the Tianbao war, the Kingdom of Nanzhao, which had unified the area around Er-hai Lake with the support of the Tang in the past, turned against the Tang and publicly announced its alliance with the Tubo. The Nanzhao Kingdom, to-gether with the Tubo, struck the Tang in the south-western region. This shift not only put the Tang in a submissive position in the southwestern region, but also significantly influenced the relations be-tween the Tang and the Tubo. As the Jiedushi of Jiannan Xichuan, Wei Gao became a unique practitioner and actively promoted a joint strategy in Yunnan. After the Tang decided to make an alliance with the Nanzhao Kingdom, relevant actions were taken immediately. However because relations between the Nanzhao Kingdom and the Tang had been broken for many years, at the beginning, Wei Gao could only communicate through some of the tribal chiefs of the Dongman ( Eastern Barbarians) . Through several years of ef-fort and mutual contact, Wei Gao’s endeavors to make an alliance with the Nanzhao, at last, were effective. Wei Gao’s efforts to make an

  12. Modelling hydraulic transport and anaerobic uptake by PAOs and GAOs during wastewater feeding in EBPR granular sludge reactors.

    Science.gov (United States)

    Weissbrodt, David G; Holliger, Christof; Morgenroth, Eberhard

    2017-03-21

    New-generation bioprocesses using granular sludge aim for a high-rate removal of nutrients from wastewater with low footprint. Achieving enhanced biological phosphorus removal (EBPR) relies on the design of sludge beds and wastewater feeding conditions to optimally load the biomass and to select for polyphosphate- (PAOs) over glycogen-accumulating organisms (GAOs) and other heterotrophs. A hydraulic-metabolic mathematical model was developed to elucidate the impact of hydraulic transport patterns and environmental conditions on the PAO/GAO competition during up-flow feeding through an EBPR granular sludge bed. Tracer experiments highlighted plug-flow regimes with dispersion under both rapid (9 m h(-1) , Rebed  = 1.6, Pez  = 7.2, Pet  = 4.6) and slow (0.9 m h(-1) , Rebed  = 0.2, Pez  = 21.3, Pet  = 3.4) feeding. Non-turbulent regimes (Rebed Feeding time, pH, and temperature significantly impacted bacterial competition for carbon uptake under anaerobic slow feeding. Feeding duration should be designed to avoid full depletion of intracellular storage polymers within static granules. PAOs bear twice longer feeding than GAOs by using both polyphosphate and glycogen hydrolysis to sustain anaerobic C-uptake. Alkaline conditions (pH 7.25-8.0) by, e.g., dosing lime in the feed select for PAOs independently of temperature (10 - 30°C). A twice higher bed is required for full anaerobic conversions at 10 rather than 20 °C. Biosystem responses for anaerobic C-uptake can be anticipated using the model toward designing robust anaerobic selectors to manage the microbial resource in EBPR granular sludge. This article is protected by copyright. All rights reserved.

  13. Kinetics of Amorphous-Crystalline Transformation of Some Se-Te-In Chalcogenide Glasses Using Gao and Wang Model

    OpenAIRE

    Balbir Singh Patial; Nagesh Thakur; S.K. Tripathi

    2013-01-01

    The present study reports the assessment of activation energy for crystallization and crystallization reaction order (Avrami exponent n) for the amorphous-crystallization transformation process of Se85 − xTe15Inx (x  2, 6 and 10) amorphous alloys using differential scanning calorimetry (DSC) technique under non-isothermal conditions at four different heating rates (5, 10, 15 and 20 °C/min) through Gao and Wang model. The introduction of In to the Se-Te system is found to bring a change in cr...

  14. LuAG:Ce fibers for high energy calorimetry

    CERN Document Server

    Dujardin, C; Ledoux, G; Perrodin, D; Ovanesyan, K L; Amans, D; Abler, D; Petrosyan, A; Auffray, E; Mancini, C

    2010-01-01

    The main objective of this contribution is to point out the potentialities of cerium doped LuAG single crystal as pixels and fibers. We first show that after optimization of growth conditions using Bridgman technology, this composition exhibits very good performances for scintillating applications (up to 26 000 photons/MeV). When grown with the micropulling down technology, fiber shapes can be obtained while the intrinsic performances are preserved. For the future high energy experiments requiring new detector concepts capable of delivering much richer informations about x- or gamma-ray energy deposition, unusual fiber shaped dense materials need to be developed. We demonstrate in this frame that cerium doped LuAG is a serious candidate for the next generation of ionizing radiation calorimeters. (C) 2010 American Institute of Physics. {[}doi: 10.1063/1.3452358

  15. First photometric study of W UMa binary star LU Lac

    Science.gov (United States)

    Liao, W.-P.; Qian, S.-B.; Zhao, E.-G.; Jiang, L.-Q.

    2014-08-01

    LU Lac is a neglected W UMa binary star in photometric investigations. In this paper, we present BVRI CCD photometric light curves obtained on one night in 2012. The first photometric solutions of this system are computed by using the Wilson-Devinney code. It is shown that LU Lac is a marginal contact W-type system with a degree of contact factor of f=8.9%, a mass ratio of q=2.085 and a high inclination of i=82°.20. From the first analyses of orbital period changes, we found the period variation of the system includes an oscillation (A3=0.0125 days and T3=51.92 years). The cyclic change may be attributed to the light-travel time effect through the presence of a third body.

  16. Uniform, luminescent Eu:LuF{sub 3} nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Becerro, Ana I., E-mail: anieto@icmse.csic.es; Gonzalez-Mancebo, Daniel; Ocaña, Manuel [Instituto de Ciencia de Materiales de Sevilla (CSIC-University of Seville) (Spain)

    2015-01-15

    A simple procedure for the synthesis of orthorhombic, uniform, LuF{sub 3} particles with two different morphologies (rhombus- and cocoon-like) and nanometer and sub-micrometer size, respectively, is reported. The method consists in the aging, at 120 °C for 2 h, a solution containing [BMIM]BF{sub 4} ionic liquid (0.5 mL) and lutetium acetate (in the case of the rhombi) or lutetium nitrate (in the case of the cocoons) (0.02 M) in ethylene glycol (total volume 10 mL). This synthesis method was also adequate for the synthesis of Eu{sup 3+}-doped LuF{sub 3} particles of both morphologies, whose luminescence properties were investigated in detail. The experimental observations reported herein suggest that these materials are suitable phosphors for optoelectronic as well as in vitro biotechnological applications.

  17. The Romanian Căluş: Symbol of National Identity

    Directory of Open Access Journals (Sweden)

    Camelia Firică

    2010-12-01

    Full Text Available Of all Romanian dances with ritual functions the most archaic and dynamic is the căluş, a custom of great complexity in its functionality and manifestation, in which dance prevails. Over the course of time, the dance aroused the admiration and interest of many scholars due to the ancient ritual elements it contains, as well as for its spectacular virtuosity and the beauty of the performance and music. The purpose of this study is to reveal the meanings and functions of the căluş, primarily at the social level, in its natural environment – the traditional Romanian village – and to make an analysis of the key moments, the logical order of the dance sequences, gestures and ritual acts, the importance of its props and of group composition and organisation.

  18. Proton emission from an oblate nucleus {sup 151}Lu

    Energy Technology Data Exchange (ETDEWEB)

    Procter, M.G., E-mail: mark.procter@postgrad.manchester.ac.uk [School of Physics and Astronomy, Schuster Laboratory, The University of Manchester, Manchester M13 9PL (United Kingdom); Cullen, D.M.; Taylor, M.J.; Alharshan, G.A. [School of Physics and Astronomy, Schuster Laboratory, The University of Manchester, Manchester M13 9PL (United Kingdom); Ferreira, L.S. [Centro de Física das Interacções Fundamentais, Departamento de Física, Instituto Superior Tecnico, Avenida Rovisco Pais, P1049-001 Lisbon (Portugal); Maglione, E. [Dipartimento di Fisica “G. Galilei”, Istituto Nazionale di Fisica Nucleare, Via Marzolo 8, I-3513, Padova (Italy); Auranen, K.; Grahn, T.; Greenlees, P.T.; Jakobsson, U.; Julin, R.; Herzáň, A.; Konki, J.; Leino, M. [Department of Physics, University of Jyväskylä, FIN-40014 Jyväskylä (Finland); Pakarinen, J. [Oliver Lodge Laboratory, University of Liverpool, Liverpool L69 7ZE (United Kingdom); Partanen, J. [Institut für Kernphysik, Universität zu Köln, D-50937, Köln (Germany); Peura, P.; Rahkila, P.; Ruotsalainen, P.; Sandzelius, M. [Department of Physics, University of Jyväskylä, FIN-40014 Jyväskylä (Finland); and others

    2013-08-09

    Excited states in the proton-unbound nucleus {sup 151}Lu have been established using γ-ray coincidence techniques. The lifetime of the first excited state above the proton-emitting ground state has been measured using the recoil-distance Doppler-shift method combined with recoil-decay tagging. The experimental level scheme and extracted lifetime have been compared with state-of-the-art theoretical calculations based upon a non-adiabatic deformed Woods–Saxon potential. This comparison suggests that the proton-emitting ground state in {sup 151}Lu is mildly oblate with a deformation β=−0.11{sub −0.05}{sup +0.02} and represents the best evidence to date for proton emission from an oblate nucleus.

  19. Biokinetic study of free {sup 177}Lu in NIH mice

    Energy Technology Data Exchange (ETDEWEB)

    Villarreal Jimenez, V.; Crudo, J., E-mail: josierys@yahoo.com [Comision Nacional de Energia Atomica (CNEA), Buenos Aires (Argentina); Rojo, A.M.; Deluca, G.M. [Autoridad Regulatoria Nuclear (ARN), Buenos Aires (Argentina)

    2008-07-01

    Full text: {sup 177}Lu has been identified, by the scientific community, as a radionuclide with interesting advantages compared with {sup 90}Y and other beta emitters used in nuclear medicine. This paper analyses the free {sup 177}Lu biokinetic behavior in NIH male mice from activity measurements performed by the Radiopharmacy Division of CNEA (Comision Nacional de Energia Atomica) in the frame of an IAEA (International Atomic Energy Agency) Coordinated Research Project. The study of experimental data is a previous condition that allows drawing the activity-time curves for organs and to know the biodistribution of {sup 177}Lu. The cumulated activity in organs of interest in NIH male mice are calculated and critical organs are identified. The organs selected for analysis in this paper are the liver, kidneys, spleen, stomach, intestine, lungs, skeleton and red marrow. The last one is estimated from the activity measured in blood based on a recognized method published by Sgouros (2000). The results has been extrapolated to human assuming the same biokinetic behaviour as mice being the applicability of the different extrapolation methods also discussed. The direct extrapolation from mice data was the method of election from a radiological protection point of view. The measurement procedures, the data processing, the extrapolation techniques and the analysis performed in this study will contribute as a basis for future research of this group in the area of antibodies and other radiopharmaceutical labeled with {sup 177}Lu. The cumulated activity calculated in each organ is relevant because it makes possible to perform the dose assessment through the application of appropriate dose coefficients. It is a necessary step in order to evaluate the toxicity risk that is required in a pre-clinical study. (author)

  20. Lattice dynamics of LuPO{sub 4}

    Energy Technology Data Exchange (ETDEWEB)

    Nipko, J.C. [Argonne National Lab., IL (United States)]|[Colorado State Univ., Fort Collins, CO (United States); Loong, C.-K. [Argonne National Lab., IL (United States); Loewenhaupt, M. [Technische Univ. Dresden (Germany); Reichardt, W.; Braden, M. [Forschungszentrum Karlsruhe GmbH Technik und Umwelt (Germany); Boatner, L.A. [Oak Ridge National Lab., TN (United States)

    1996-06-01

    Lutetium orthophosphate is an important nonmagnetic host material for rare-earth-activated luminescence applications. We have measured the LuPO{sub 4} phonon density of states and dispersion curves along the [{xi}00],[{xi}{xi}0], and [00{xi}] symmetry directions by neutron spectroscopy using polycrystalline and single-crystal samples. A quantitative analysis of the neutron results was carried out using a lattice-dynamical shell model.

  1. Shape evolution with angular momentum in Lu isotopes

    Science.gov (United States)

    Kardan, Azam; Sayyah, Sepideh

    2016-06-01

    The nuclear potential energies of Lu isotopes with neutron number N = 90 - 98 up to high spins are computed within the framework of the unpaired cranked Nilsson-Strutinsky method. The potential and the macroscopic Lublin-Strasbourg drop (LSD) energy-surface diagrams are analyzed in terms of quadrupole deformation and triaxiality parameter. The shape evolution of these isotopes with respect to angular momentum, as well as the neutron number is studied.

  2. Automatic Blocking Of QR and LU Factorizations for Locality

    Energy Technology Data Exchange (ETDEWEB)

    Yi, Q; Kennedy, K; You, H; Seymour, K; Dongarra, J

    2004-03-26

    QR and LU factorizations for dense matrices are important linear algebra computations that are widely used in scientific applications. To efficiently perform these computations on modern computers, the factorization algorithms need to be blocked when operating on large matrices to effectively exploit the deep cache hierarchy prevalent in today's computer memory systems. Because both QR (based on Householder transformations) and LU factorization algorithms contain complex loop structures, few compilers can fully automate the blocking of these algorithms. Though linear algebra libraries such as LAPACK provides manually blocked implementations of these algorithms, by automatically generating blocked versions of the computations, more benefit can be gained such as automatic adaptation of different blocking strategies. This paper demonstrates how to apply an aggressive loop transformation technique, dependence hoisting, to produce efficient blockings for both QR and LU with partial pivoting. We present different blocking strategies that can be generated by our optimizer and compare the performance of auto-blocked versions with manually tuned versions in LAPACK, both using reference BLAS, ATLAS BLAS and native BLAS specially tuned for the underlying machine architectures.

  3. Development of 177Lu-phytate Complex for Radiosynovectomy

    Directory of Open Access Journals (Sweden)

    Hassan Yousefnia

    2013-05-01

    Full Text Available Objective(s: In this work a new possible agent for radiosynovectomy has been targeted for articular pain palliation. Materials and Methods: Lu-177 of 2.6-3 GBq/mg specific activity was obtained by irradiation of natural Lu2O3 sample with thermal neutron flux of 4 × 1013 n.cm-2.s-1. The product was converted into chloride form which was further used for labeling of 177Lu-phytate complex and checked using ITLC (MeOH: H2O: acetic acid, 4: 4: 2, as mobile phase. The complex stability and viscosity were checked in the final solution up to seven days. The prepared complex solution (100 µCi/100 µl was injected intra-articularly to male rat knee joint. Leakage of radioactivity from injection site and its distribution in organs were investigated up to seven days. Results: The complex was successfully prepared with high radiochemical purity (>99.9 %. Approximately, the whole injected dose has remained in injection site seven days after injection. Conclusion: The complex was proved to be a feasible agent for cavital radiotherapy in oncology and rheumatology

  4. Cases of Vertigo Treated by Professor Gao Ying%高颖教授治疗眩晕验案举隅

    Institute of Scientific and Technical Information of China (English)

    王羽侬; 高颖

    2014-01-01

    高颖教授从事中医临床工作多年,临床经验丰富,针对眩晕的不同病因进行治疗,疗效颇佳。本文记录四则验案,并逐一分析了高教授的诊疗思路及用药特点。%Professor.Gao Ying has been engaged in the clinical work of traditional Chinese medicine for many years,and she has rich clinical experiences,especially in the treatment of vertigo according to different etiology,which has good clinical effects.This article in-troduces four cases treated by Prof.Gao Ying,analyzes the approaches to the diagnosis and the characteristics of formulas of Prof.Gao Ying.

  5. An antibody to the lutheran glycoprotein (Lu recognizing the LU4 blood type variant inhibits cell adhesion to laminin α5.

    Directory of Open Access Journals (Sweden)

    Yamato Kikkawa

    Full Text Available BACKGROUND: The Lutheran blood group glycoprotein (Lu, an Ig superfamily (IgSF transmembrane receptor, is also known as basal cell adhesion molecule (B-CAM. Lu/B-CAM is a specific receptor for laminin α5, a major component of basement membranes in various tissues. Previous reports have shown that Lu/B-CAM binding to laminin α5 contributes to sickle cell vaso-occlusion. However, as there are no useful tools such as function-blocking antibodies or drugs, it is unclear how epithelial and sickled red blood cells adhere to laminin α5 via Lu/B-CAM. METHODOLOGY/PRINCIPAL FINDINGS: In this study, we discovered a function-blocking antibody that inhibits Lu binding to laminin α5 using a unique binding assay on tissue sections. To characterize the function-blocking antibody, we identified the site on Lu/B-CAM recognized by this antibody. The extracellular domain of Lu/B-CAM contains five IgSF domains, D1-D2-D3-D4-D5. The antibody epitope was localized to D2, but not to the D3 domain containing the major part of the laminin α5 binding site. Furthermore, mutagenesis studies showed that Arg(175, the LU4 blood group antigenic site, was crucial for forming the epitope and the antibody bound sufficiently close to sterically hinder the interaction with α5. Cell adhesion assay using the antibody also showed that Lu/B-CAM serves as a secondary receptor for the adhesion of carcinoma cells to laminin α5. CONCLUSION/SIGNIFICANCE: This function-blocking antibody against Lu/B-CAM should be useful for not only investigating cell adhesion to laminin α5 but also for developing drugs to inhibit sickle cell vaso-occlusion.

  6. Primary standardization of a {sup 177}Lu solution; Padronizacao primaria de uma solucao de {sup 177}Lu

    Energy Technology Data Exchange (ETDEWEB)

    Iwahara, Akira; Silva, Carlos Jose da; Tauhata, Luiz; Oliveira, Estela Maria de, E-mail: iwahara@ird.gov.b, E-mail: carlos@ird.gov.b, E-mail: tauhata@ird.gov.b, E-mail: estela@ird.gov.b [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Rezende, Eduarda Alexandre, E-mail: eduarda@ird.gov.b [Centro Federal de Educacao Tecnologica de Quimica (CEFET), Nilopolis, RJ (Brazil)

    2009-07-01

    For the purpose to make available reliable standards of {sup 177}Lu to the users and producers, a radionuclide solution was standardized using the primary methods of coincidence 4{pi}{beta}(PC)-{gamma}(NaI(Tl)) and of 4{pi}{beta}(LS)-{gamma}(NaI(Tl)). The results presented a convergence in the range of evaluated uncertainties. The standard uncertainties were of the 0.50 and 0.74% for the anticoincidence and coincidence respectively

  7. [On the lecture on the history of anatomy which Lu Xun heard in Sendai].

    Science.gov (United States)

    Sakai, Tatsuo

    2008-12-01

    In "Fujino Sensei," Lu Xun wrote that in his first lecture on anatomy, osteology Professor Fujino talked about the history of anatomy in Japan; although Lu Xun's extant lecture notes do not show any mention of Fujino's comments on the history of anatomy. However, since the lecture notes of senior students mention the history of anatomy, we do not find any reason to assume that Lu Xun did not hear about the history of anatomy in the lecture. Furthermore, the timetable of lectures indicates that the first lecture of anatomy was attributed to Professor Fujino. It is concluded that the description of the first anatomical lecture in "Fujino Sensei" was written based on Lu Xun's actual experience. The lecture on the history of anatomy which Lu Xun heard was made by Professor Fujino; probably based on a lecture by Professor Shikinami which was recorded in the notes of Saito Ryusho, a student who was three years senior to Lu Xun.

  8. LuF[SeO3]: the structural chameleon of lanthanoid fluoride oxoselenates(IV).

    Science.gov (United States)

    Lipp, Christian; Dinnebier, Robert E; Schleid, Thomas

    2013-10-07

    LuF[SeO3] is a compound that can easily be obtained by a solid-state reaction of Lu2O3, LuF3, and SeO2 with CsBr as the fluxing agent. The outstanding property of LuF[SeO3] is the appearance of two phase transitions within a range of less than 200 K. With an increase in the coordination number for Lu(3+) from 7 to 8, the triclinic room-temperature modification changes at temperatures below -40 °C to the monoclinic low-temperature or high-pressure phase of LuF[SeO3]. At the same time, room-temperature modification retains the structure but gains higher symmetry at the second phase transition of around +110 °C. This second transition can even be observed under a microscope using polarized light to see twinning lamellae disappear and reappear during this reversible process.

  9. LuIII parvovirus selectively and efficiently targets, replicates in, and kills human glioma cells.

    Science.gov (United States)

    Paglino, Justin C; Ozduman, Koray; van den Pol, Anthony N

    2012-07-01

    Because productive infection by parvoviruses requires cell division and is enhanced by oncogenic transformation, some parvoviruses may have potential utility in killing cancer cells. To identify the parvovirus(es) with the optimal oncolytic effect against human glioblastomas, we screened 12 parvoviruses at a high multiplicity of infection (MOI). MVMi, MVMc, MVM-G17, tumor virus X (TVX), canine parvovirus (CPV), porcine parvovirus (PPV), rat parvovirus 1A (RPV1A), and H-3 were relatively ineffective. The four viruses with the greatest oncolytic activity, LuIII, H-1, MVMp, and MVM-G52, were tested for the ability, at a low MOI, to progressively infect the culture over time, causing cell death at a rate higher than that of cell proliferation. LuIII alone was effective in all five human glioblastomas tested. H-1 progressively infected only two of five; MVMp and MVM-G52 were ineffective in all five. To investigate the underlying mechanism of LuIII's phenotype, we used recombinant parvoviruses with the LuIII capsid replacing the MVMp capsid or with molecular alteration of the P4 promoter. The LuIII capsid enhanced efficient replication and oncolysis in MO59J gliomas cells; other gliomas tested required the entire LuIII genome to exhibit enhanced infection. LuIII selectively infected glioma cells over normal glial cells in vitro. In mouse models, human glioblastoma xenografts were selectively infected by LuIII when administered intratumorally; LuIII reduced tumor growth by 75%. LuIII also had the capacity to selectively infect subcutaneous or intracranial gliomas after intravenous inoculation. Intravenous or intracranial LuIII caused no adverse effects. Intracranial LuIII caused no infection of mature mouse neurons or glia in vivo but showed a modest infection of developing neurons.

  10. Gamma radiation exposure of accompanying persons due to Lu-177 patients

    Science.gov (United States)

    Kovan, Bilal; Demir, Bayram; Tuncman, Duygu; Capali, Veli; Turkmen, Cuneyt

    2015-07-01

    Neuroendocrine tumours (NET) are cancers usually observed and arisen in the stomach, intestine, pancreas and breathing system. Recently, radionuclide therapy applications with Lu-177 peptide compound are rapidly growing; especially effective clinical results are obtained in the treatment of well-differentiated and metastatic NET. In this treatment, Lu-177-DOTA, a beta emitter radioisotope in the radiopharmaceutical form, is given to the patient by intravenous way. Lu-177 has also gamma rays apart from beta rays. Gamma rays have 175 keV average energy and these gamma rays should be under the control in terms of radiation protection. In this study, we measured the exposure dose from the Lu-177 patient.

  11. The role of phosphates for the Lu-Hf chronology of meteorites

    Science.gov (United States)

    Debaille, Vinciane; Van Orman, James; Yin, Qing-Zhu; Amelin, Yuri

    2017-09-01

    The 176Lu-176Hf isotopic system is widely used for dating and tracing cosmochemical and geological processes, but still suffers from two uncertainties. First, Lu-Hf isochrons for some early Solar System materials have excess slope of unknown origin that should not be expected for meteorites with ages precisely determined with other isotopic chronometers. This observation translates to an apparent Lu decay constant higher than the one calculated by comparing ages obtained with various dating methods on terrestrial samples. Second, unlike the well constrained Sm/Nd value (to within 2%) for the chondritic uniform reservoir (CHUR), the Lu/Hf ratios in chondrites vary up to 18% when considering all chondrites, adding uncertainty to the Lu/Hf CHUR value. In order to better understand the Lu-Hf systematics of chondrites, we analyzed mineral fractions from the Richardton H5 chondrite to construct an internal Lu-Hf isochron, and set up a numerical model to investigate the effect of preferential diffusion of Lu compared to Hf from phosphate, the phase with the highest Lu-Hf ratio in chondrites, to other minerals. The isochron yields an age of 4647 ± 210 million years (Myr) using the accepted 176Lu decay constant of 1.867 ± 0.008 ×10-11yr-1. Combining this study with the phosphate fractions measured in a previous study yields a slope of 0.08855 ± 0.00072, translating to a 176Lu decay constant of 1.862 ± 0.016 ×10-11yr-1 using the Pb-Pb age previously obtained, in agreement with the accepted value. The large variation of the Lu/Hf phosphates combined with observations in the present study identify phosphates as the key in perturbing Lu-Hf dating and generating the isochron slope discrepancy. This is critical as apatite has substantially higher diffusion rates of rare earth elements than most silicate minerals that comprise stony meteorites. Results of numerical modeling depending of temperature peak, size of the grains and duration of the metamorphic event, show that

  12. Scintillation and luminescence properties of Sm3+-activated Lu2O3-CaO-SiO2-B2O3 (LuCSB) scintillating glasses

    Science.gov (United States)

    Kirdsiri, K.; Kaewkhao, J.; Park, J. M.; Ha, D. H.

    2016-09-01

    Lutetium (Lu) is a high atomic number material and readily interacts with X-rays, which makes it a good scintillation material. In this work, Lu-glass scintillators from the series xSm2O3: 25Lu2 O3: 10SiO2: 10CaO: (55- x)B2O3 (LuCSB) were synthesized at 1500 ° C by using a simple melt quenching technique. The influence of the Sm3+ ion on their physical, optical, photo-, X-rayand proton-induced properties has been characterized. The amorphous nature of the samples was confirmed by using X-ray diffraction. The density and the molar volume were found to be increased at higher concentrations of Sm3+. The X-ray- and the proton-induced emission spectra of the Sm3+:LuCSB glasses showed an intense reddish-orange emission around 604 nm (4G5/2 → 6H7/2), which matched the photoluminescence (PL) emission spectrum well. Among the prepared glasses, the 1.0-mol% Sm3+ ion-activated LuCSB glass exhibited the highest value of the characteristic emission parameters. The X-ray-induced luminescence of the LuCSB glass was also compared with that of a commercial bismuth germinate Bi4Ge3O12 (BGO) crystal.

  13. A propósito de José Gaos: una sociofilosofía de un transterrado

    Directory of Open Access Journals (Sweden)

    Blanca Muñoz

    2005-03-01

    Full Text Available Para el autor de «Historia de nuestra idea del mundo», los puntos de referencia de cada cultura establecen el pensamiento reflexivo de cada sociedad en un momento concreto de su formación. De esta manera, la Sociología del Conocimiento y la Sociología de la Cultura coinciden en la Historia del pensamiento español. Esta va a ser una de las grandes aportaciones de Gaos al pensamiento español e hispanoamericano como lo reconocerá el mismo Octavio Paz. Pero lo auténticamente original de todo este planteamiento gnoseológico va a provenir del hecho según el cual la conciencia intelectual establece sus puntos de referencia sobre la conciencia cultural de la comunidad. Estamos ante una Sociología culturalista que abre el horizonte del conocimiento de una época a partir de sus representaciones sensibles, ya que estas representaciones sensibles y estéticas, no obstante, son los resultados de unos acontecimientos sociales sobre los que se cimenta la estructura simbólica de cada sociedad considerada como sistema, tal y como Ortega comprendía la Historia. En suma, para la Sociofilosofía o Filosociología de José Gaos, la convergencia entre lo europeo y lo hispano nace de la concepción de nuestra idea del mundo desde el punto de vista de las múltiples encrucijadas en las que ésta se ha ido conformando. Con ello, Gaos crea una nueva Sociología de la Cultura y del Conocimiento en la que su obra surge como el punto de unión entre la cultura europea y la cultura hispanoamericana a partir de la revalorización de la síntesis entre creación estética y literaria y reflexión filosófica y social.

  14. Lu-177-Labeled Zirconia Particles for Radiation Synovectomy.

    Science.gov (United States)

    Polyak, Andras; Nagy, Lívia Naszályi; Drotár, Eszter; Dabasi, Gabriella; Jóba, Róbert P; Pöstényi, Zita; Mikolajczak, Renata; Bóta, Attila; Balogh, Lajos

    2015-12-01

    The present article describes the preparation of β-emitter lutetium-177-labeled zirconia colloid and its preliminary physicochemical and biological evaluation of suitability for local radionuclide therapy. The new (177)Lu-labeled therapeutic radiopharmaceutical candidate was based on the synthesis mode of a previously described zirconia nanoparticle system. The size and shape of the developed radiopharmaceutical compound were observed through a scanning electron microscope and dynamic light scattering methods. The radiocolloid had a 1.7 μm mean diameter and showed high in vitro radiochemical and colloid size stability at room temperature and during the blood sera stability test. After the in vitro characterizations, the product was investigated in the course of the treatment of a spontaneously diseased dog veterinary patient's hock joint completed with single-photon emission computed tomography (SPECT) imaging follow-up measurements and a dual-isotope SPECT imaging tests with conventional (99m)Tc-methanediphosphonic acid bone scintigraphy. In the treated dog, no clinical side-effects or signs of histopathological changes of the joints were recorded during the treatment. SPECT follow-up studies clearly and conspicuously showed the localization of the (177)Lu-labeled colloid in the hock joint as well as detectable but negligible leakages of the radiocolloid in the nearest lymph node. On the basis of biological follow-up tests, the orthopedic team assumed that the (177)Lu-labeled zirconia colloid-based local radionuclide therapy resulted in a significant and long-term improvement in clinical signs of the patient without any remarkable side-effects.

  15. District of Columbia Opportunity Scholarship Program: Additional Policies and Procedures Would Improve Internal Controls and Program Operations. Report to Congressional Requesters. GAO-08-9

    Science.gov (United States)

    Ashby, Cornelia M.; Franzel, Jeanette M.

    2007-01-01

    The D.C. School Choice Incentive Act created the first private kindergarten-through-grade-12 school-choice program supported by federal funds. The program was named the D.C. Opportunity Scholarship Program (OSP). The United States Government Accountability Office (GAO) was asked to assess the (1) accountability mechanisms governing the use of…

  16. Eesti ja hiina keel pärinevad ühest allikast : hiina keeleteadlane Gao Jingyi jätkab uurimistööd Eestis / Raimu Hanson

    Index Scriptorium Estoniae

    Hanson, Raimu, 1957-

    2009-01-01

    Hiina keeleteadlane Gao Jingyi on avaldanud raamatu, milles ta näitab, et hiina keel ning eesti keel ja teised läänemeresoome keeled mingil määral koos teiste uurali keeltega pärinevad ühisest allikast

  17. Eesti ja hiina keel pärinevad ühest allikast : hiina keeleteadlane Gao Jingyi jätkab uurimistööd Eestis / Raimu Hanson

    Index Scriptorium Estoniae

    Hanson, Raimu, 1957-

    2009-01-01

    Hiina keeleteadlane Gao Jingyi on avaldanud raamatu, milles ta näitab, et hiina keel ning eesti keel ja teised läänemeresoome keeled mingil määral koos teiste uurali keeltega pärinevad ühisest allikast

  18. Higher Education: Improved Tax Information Could Help Families Pay for College. Report to the Committee on Finance, U.S. Senate. GAO-12-560

    Science.gov (United States)

    White, James R.; Scott, George A.

    2012-01-01

    The federal government provides billions of dollars in assistance each year to students and families through federal student aid programs authorized under Title IV of the Higher Education Act of 1965 and through tax expenditures, such as credits and deductions. GAO was asked to (1) describe the size and distribution of Title IV student aid and tax…

  19. District of Columbia Charter Schools: Criteria for Awarding School Buildings to Charter Schools Needs Additional Transparency. Report to Congressional Committees. GAO-11-263

    Science.gov (United States)

    Scott, George A.

    2011-01-01

    Almost 40 percent of all public school students in the District of Columbia (D.C. or District) were enrolled in charter schools in the 2010-11 school year. The D.C. School Reform Act established the Public Charter School Board (PCSB) for the purpose of authorizing and overseeing charter schools. Congress required GAO (US Government Accountability…

  20. Conversion coefficient measurements of 176Lu using ICEBall

    Science.gov (United States)

    Battaglia, Anthony A.

    We have studied the multipolarites of several transitions in the nucleus 176Lu. The synthesis of 176Lu in stellar environments is through the slow (s-) neutron capture process. The s-process is responsible for the creation of 50% of the heavy elements and 15-20 nuclei in the s-process are s-process branching points. Branching points determine if the synthesis path will beta-decay or neutron capture. The branching point 176 Lu is only produced via the s-process only and has both a long-lived ground state (K = 7--) of 37.6 Gy and a short-lived isomeric state (K = 0--) at 3.6 h. There is no direct decay to both the isomer and ground state due to selection rules. However, an intermediate state was found at 839 keV in the K = 4-- band and another intermediate state in the K = 4+ band at 709 keV which communicate to both the isomer and ground state. The communication to both the isomer and ground state through the intermediate states affects the final abundances of 176Lu in stellar environments which is sensitive to temperature. The experiment was performed at the University of Notre Dame Nuclear Science Laboratory (NSL) using a 176Yb(p,n) reaction at 7.75 MeV. Gamma-gamma and gamma-electron coincidences were measured for conversion coefficients using the Internal Conversion Electron Ball (ICEBall) array and two HPGe detectors (109% relative efficiency of a 3"x 3" NaI detector at 1332 keV). ICEBall was upgraded at the NSL for an improved efficiency from 6%-15% over 4. A total of 40 conversion cofficcients were measured and 35 multipolarities wer assigned. 17 new conversion coefficients were measured and the corresponding multipolarities were assigned. Levels and spin assignments in both the K = 4+ band and K = 4-- band were verified in the intermediate states that are important for establishing a thermal equilibrium in the s-process.

  1. Introducing multiple treatment plan-based comparison to investigate the performance of gantry angle optimisation (GAO) in IMRT for head and neck cancer

    Energy Technology Data Exchange (ETDEWEB)

    Thor, Maria [Depts. of Oncology and Medical Physics, Aarhus Univ. Hospital, Aarhus (Denmark); Dept. of Clinical Medicine, Aarhus Univ., Aarhus, (Denmark); Medical Radiation Physics, Dept. of Clinical Sciences Lund, Lund Univ., Lund (Sweden)], e-mail: mariator@rm.dk; Benedek, Hunor; Knoeoes, Tommy; Engstroem, Per [Medical Radiation Physics, Dept. of Clinical Sciences Lund, Lund Univ., Lund (Sweden); Radiation Physics, Skaane Univ. Hospital, Lund (Sweden); Behrens, Claus F. [Div. of Radiophysics, Copenhagen Univ. Hospital Herlev, Herlev (Denmark); Karlsson Hauer, Anna [Div. of Radiophysics, Copenhagen Univ. Hospital Herlev, Herlev (Denmark); Dept of Therapeutic Radiophysics, Sahlgrenska Univ. Hospital, Gothenburg (Sweden); Sjoestroem, David [Div. of Radiophysics, Copenhagen Univ. Hospital Herlev, Herlev (Denmark); Ceberg, Crister [Medical Radiation Physics, Dept. of Clinical Sciences Lund, Lund Univ., Lund (Sweden)

    2012-07-15

    Background and purpose: The purpose of this study was to evaluate the performance of gantry angle optimisation (GAO) compared to equidistant beam geometry for two inverse treatment planning systems (TPSs) by utilising the information obtained from a range of treatment plans. Material and methods: The comparison was based on treatment plans generated for four different head and neck (HandN) cancer cases using two inverse treatment planning systems (TPSs); Varian Eclipse representing dynamic MLC intensity modulated radiotherapy (IMRT) and Oncentra Masterplan representing segmented MLC-based IMRT. The patient cases were selected on the criterion of representing different degrees of overlap between the planning target volume (PTV) and the investigated organ at risk, the ipsilateral parotid gland. For each case, a number of 'Pareto optimal' plans were generated in order to investigate the trade-off between the under-dosage to the PTV (VPTV, D < 95%) or the decrease in dose homogeneity (D5-D95) to the PTV as a function of the mean absorbed dose to the ipsilateral parotid gland (parotid gland). Results: For the Eclipse system, GAO had a clear advantage for the cases with smallest overlap (Cases 1 and 2). The set of data points, representing the underlying trade-offs, generated with and without using GAO were, however, not as clearly separated for the cases with larger overlap (Cases 3 and 4). With the OMP system, the difference was less pronounced for all cases. The Eclipse GAO displays the most favourable trade-off for all HandN cases. Conclusions: We have found differences in the effectiveness of GAO as compared to equidistant beam geometry, in terms of handling conflicting trade-offs for two commercial inverse TPSs. A comparison, based on a range of treatment plans, as developed in this study, is likely to improve the understanding of conflicting trade-offs and might apply to other thorough comparison techniques.

  2. Negative thermal expansion and anomalies of heat capacity of LuB50 at low temperatures.

    Science.gov (United States)

    Novikov, V V; Zhemoedov, N A; Matovnikov, A V; Mitroshenkov, N V; Kuznetsov, S V; Bud'ko, S L

    2015-09-28

    Heat capacity and thermal expansion of LuB50 boride were experimentally studied in the 2-300 K temperature range. The data reveal an anomalous contribution to the heat capacity at low temperatures. The value of this contribution is proportional to the first degree of temperature. It was identified that this anomaly in heat capacity is caused by the effect of disorder in the LuB50 crystalline structure and it can be described in the soft atomic potential model (SAP). The parameters of the approximation were determined. The temperature dependence of LuB50 heat capacity in the whole temperature range was approximated by the sum of SAP contribution, Debye and two Einstein components. The parameters of SAP contribution for LuB50 were compared to the corresponding values for LuB66, which was studied earlier. Negative thermal expansion at low temperatures was experimentally observed for LuB50. The analysis of the experimental temperature dependence for the Gruneisen parameter of LuB50 suggested that the low-frequency oscillations, described in SAP mode, are responsible for the negative thermal expansion. Thus, the glasslike character of the behavior of LuB50 thermal characteristics at low temperatures was confirmed.

  3. Influence of magnetic on ferroelectric ordering in LuMnO3

    NARCIS (Netherlands)

    Van Aken, BB; Palstra, TTM

    2004-01-01

    We have studied the influence of antiferromagnetic ordering on the local dielectric moments of the MnO5 and LuO7 polyhedra by measuring neutron powder-diffraction patterns of LuMnO3 at temperatures near T-N. We show that the coupling is weak, because the magnetic exchange coupling is predominantly i

  4. Lu AA21004, a novel multimodal antidepressantwith activity exerted through serotonergic targets

    DEFF Research Database (Denmark)

    Mork, A.; Pehrson, A.; Montezinho, L. C. P.;

    2012-01-01

    Background: Lu AA21004 is a multimodal antidepressant that functions as a 5-HT3 and 5-HT7 receptor antagonist, 5-HT1B receptor partial agonist, 5-HT1A receptor agonist and inhibitor of the 5-HT transporter in vitro. Here we investigated preclinical effects of Lu AA21004 1) on target occupancies, 2...

  5. Port-Hamiltonian description and analysis of the LuGre friction model

    NARCIS (Netherlands)

    Koopman, J.; Jeltsema, D.; Verhaegen, M.H.G.

    2010-01-01

    A port-Hamiltonian formulation of the LuGre friction model is presented that can be used as a building block in the physical modelling of systems with friction. Based on the dissipation structure matrix of this port-Hamiltonian LuGre model, an alternative proof can be given for the passivity conditi

  6. Whole Body Activity Retentions in the Peptide Receptor Radionuclide Therapy with Lu-177

    NARCIS (Netherlands)

    Liu, B.

    2013-01-01

    The patients with the neuroendocrine tumours (liver, spleen, etc.) often need treatment by the Peptide Receptor Radionuclide Therapy with 177Lu. The amount of 177Lu activity in the body of patients has to be known accurately for assessment of the dosimetry and for evaluation of the effectiveness of

  7. Beta-glycosidase (amygdalase and linamarase) from Endomyces fibuliger (LU677): formation and crude enzymes properties.

    NARCIS (Netherlands)

    Brimer, L.; Nout, M.J.R.; Tuncel, G.

    1998-01-01

    In our previous studies, the yeast Endomyces fibuliger LU677 was found to degrade amygdalin in bitter apricot seeds. The present investigation shows that E. fibuliger LU677 produces extracellular beta-glycosidase activity when grown in malt extract broth (MEB). Growth was very good at 25 degrees C

  8. Europium gallium garnet (Eu3Ga5O12) and Eu3GaO6: Synthesis and material properties

    Science.gov (United States)

    Sawada, Kenji; Nakamura, Toshihiro; Adachi, Sadao

    2016-10-01

    Eu-Ga-O ternary compounds were synthesized from a mixture of cubic (c-) Eu2O3 and monoclinic Ga2O3 (β-Ga2O3) raw powders using the solid-state reaction method by calcination at Tc = 1200 °C. The structural and optical properties of the Eu-Ga-O ternary compounds were investigated using X-ray diffraction analysis, photoluminescence (PL) analysis, PL excitation (PLE) spectroscopy, and Raman scattering measurements. Stoichiometric compounds such as cubic Eu3Ga5O12 (EGG) and orthorhombic Eu3GaO6 were synthesized using molar ratios of x = 0.375 and 0.75 [x≡Eu2O3/(Eu2O3 + Ga2O3)], respectively, together with the end-point binary compounds β-Ga2O3 (x = 0) and monoclinic (m-) Eu2O3 (x = 1.0). The structural change from "cubic" to "monoclinic" in Eu2O3 is due to the structural phase transition occurring at Tc ≥ 1050 °C. In principle, the perovskite-type EuGaO3 and monoclinic Eu4Ga2O9 can also be synthesized at x = 0.5 and 0.667, respectively; however, such stoichiometric compounds could not be synthesized in this study. The PL and PLE properties of EGG and Eu3GaO6 were studied in detail. The temperature dependence of the PL spectra was observed through measurements carried out between T = 20 and 300 K and explained using a newly developed model. Raman scattering measurements were also performed on the Eu-Ga-O ternary systems over the entire composition range from x = 0 (β-Ga2O3) to 1.0 (m-Eu2O3).

  9. Femtosecond Spectroscopy of LuMnO3

    Science.gov (United States)

    Lou, Shitao; Zimmermann, Frank M.; Bartynski, Robert A.; Hur, Namjun; Cheong, Sang-Wook

    2006-03-01

    Hexagonal LuMnO3 manganite is a ferroelectric and strongly frustrated antiferromagnetic crystal. Strong coupling between lattice, electronic, and magnetic degrees of freedom makes it a promising electronic material. We have used femtosecond pump-probe spectroscopy to study the interaction of electron excitations with lattice vibrations in real time. Optical excitation of a Mn d(x^2-y^2),(xy)->d(3z^2-r^2)transition served as the primary excitation step. With both pump and probe beam polarization perpendicular to the c axis, the probe reflectivity shows a sharp drop due to saturation of the transition, recovering on a timescale of 1 ps. We also observed displacive excitation of a coherent optical phonon vibration at 3.6 THz, which is assigned to an A1 symmetry mode involving Lu ion motion along the c axis. This mode was excited in longitudinal (LO) and transverse mode (TO) geometries. While the LO-TO frequency splitting is small (<0.1 THz), a remarkable phase reversal of the reflectivity curve was observed. This is attributed to a large linear electro-optic effect (Pockels effect), induced by the THz electric field associated with the LO mode.

  10. Green and red luminescence in co-precipitation synthesized Pr:LuAG nanophosphor

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, S. Arun; Kumar, K. Ashok; Gunaseelan, M.; Senthilselvan, J., E-mail: jsselvan@hotmail.com [Department of Nuclear Physics, University of Madras, Guindy Campus, Chennai–600 025, Tamil Nadu (India); Asokan, K. [Materials Science Group, Inter University Accelerator Centre, New Delhi-110067 (India)

    2016-05-06

    Pr:LuAG nanophosphor is an effective candidate in magnetic resonance imaging coupled positron emission tomography (MRI-PET) for medical imaging and scintillator applications. LuAG:Pr (0.05, 0.15 mol%) nanoscale ceramic powders were synthesized by co-precipitation method using urea as precipitant. Effect of antisite defect on structure and luminescence behavior was investigated. Pr:LuAG nanoceramic powders are found crystallized in cubic structure by high temperature calcination at 1400 °C and it shows antisite defect. HR-SEM analysis revealed spherically shaped Pr:LuAG nanoceramic particulate powders with ∼100 nm size. By the excitation at 450 nm, Pr:LuAG nanophosphor exhibit green to red luminescence in the wavelength range of 520 to 680 nm, which is originated from multiplet transition of Pr{sup 3+} ions.

  11. Magnetic properties of Ho1- x Lu x B12 solid solutions

    Science.gov (United States)

    Gabáni, S.; Gaz̆o, E.; Pristás̆, G.; Takác̆ová, I.; Flachbart, K.; Shitsevalova, N.; Siemensmeyer, K.; Sluchanko, N.

    2013-05-01

    Magnetic properties of the geometrically frustrated antiferromagnet HoB12 (with T N = 7.4 K) modified by substitution of magnetic Ho atoms through non-magnetic Lu ones are presented and discussed. In this case, in Ho1- x Lu x B12 solid solutions, both chemical pressure resulting from different Lu3+ and Ho3+ radii and magnetic dilution take place with increasing Lu content ( x) that change properties of the system. The received results show strong indication for the existence of a quantum critical point near x = 0.9, which separates the region of magnetic order (starting with HoB12 for x = 0) and the nonmagnetic region (ending with superconducting LuB12 for x = 1).

  12. Lu AA21004, a novel multimodal antidepressantwith activity exerted through serotonergic targets

    DEFF Research Database (Denmark)

    Mork, A.; Pehrson, A.; Montezinho, L. C. P.

    2012-01-01

    (5-HT), noradrenaline (NA), dopamine (DA), acetylcholine (ACh), histamine (Hist)] were measured by microdialysis. Antidepressant potential was assessed in the forced swim test using Flinders Sensitive Line (FSL) rats. Moreover, effects of Lu AA21004 on acquisition, consolidation and recall...... of contextual memory in rats were studied in the fear conditioning paradigm, and episodic memory was evaluated in the novel object recognition test. Results: Administration of Lu AA21004 (0.1-10 mg/kg, sc) demonstrated that the compound dose-dependently occupied the studied targets. Moreover, Lu AA21004...... increased extracellular levels of 5-HT, NA, DA, ACh and Hist in the brain. Lu AA21004 counteracted the immobility of FSL rats in the forced swim test and enhanced memory of the rats in the cognition models. Conclusions: Lu AA21004 in vivo engages relevant targets and affects several neurotransmitter systems...

  13. Biferroic LuCrO{sub 3}: Structural characterization, magnetic and dielectric properties

    Energy Technology Data Exchange (ETDEWEB)

    Durán, A., E-mail: dural@cnyn.unam.mx [Universidad Nacional Autónoma de México, Centro de Nanociencias y Nanotecnología, Km. 107 Carretera Tijuana-Ensenada, Apartado Postal 14, C.P. 22800 Ensenada, BC (Mexico); Meza F, C.; Morán, E.; Alario-Franco, M.A. [Departamento de Química Inorgánica y Laboratorio Complutense de Altas Presiones, Facultad de Química, Universidad Complutense de Madrid, EU, 28040 Madrid (Spain); Ostos, C., E-mail: ceostoso@gmail.com [Instituto de Química, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín (Colombia)

    2014-02-14

    Multiferroic LuCrO{sub 3} perovskite-type structure (Pbnm) obtained via auto-ignition synthesis was characterized by a combination of X-ray diffraction (XRD) and thermogravimetric (TG) techniques, and through magnetization and permittivity measurements. Results showed that amorphous combustion powders were fully transformed to orthorhombic LuCrO{sub 3} structure at 1200 K after the first LuCrO{sub 4} crystallization at 700 K. The magnetic response displays thermal irreversibility between zero-field-cooling and field-cooling condition which is due to spin canted AF switching at 116 K. Accordingly, a hysteresis loop in the M(H) data confirms weak ferromagnetism in LuCrO{sub 3}. On the other hand, the permittivity measurement shows a broad peak transition typical of relaxor-type ferroelectrics transition at ∼450 K. Electrical conductivity increases as temperature increases showing an anomaly around the diffuse phase transition. The diffuse phase transition and the formation of the charge carriers are discussed in terms of a local distortion around the Lu Site. - Highlights: • Multiferroic LuCrO{sub 3} was successfully obtained via auto-ignition synthesis. • Amorphous powder is transformed first to LuCrO{sub 4} (700 K) and next to LuCrO{sub 3} (1100 K). • The CrO{sub 6} octahedra are tilted away and rotates from the ideal octahedral shape. • LuCrO{sub 3} exhibits a canted AFM transition (116 K) and a relaxor ferroelectric behavior. • Tilting and rotation of CrO{sub 6} octahedra influenced transport properties on LuCrO{sub 3}.

  14. Production of {sup 177}Lu for targeted radionuclide therapy: Available options

    Energy Technology Data Exchange (ETDEWEB)

    Dah, Ashutosh [Isotope Production and Applications Division, Bhabha Atomic Research Centre (BARC), Mumbai (India); Pillai, Maroor Raghavan Ambikalmajan [Molecular Group of Companies. Kerala (India); Knapp, Furn F. Jr. [Medical Isotopes Program, Isotope Dept. Group, Oak Ridge National Laboratory (ORNL), Oak Ridge (United States)

    2015-06-15

    This review provides a comprehensive summary of the production of {sup 177}Lu to meet expected future research and clinical demands. Availability of options represents the cornerstone for sustainable growth for the routine production of adequate activity levels of {sup 177}Lu having the required quality for preparation of a variety of {sup 177}Lu-labeled radiopharmaceuticals. The tremendous prospects associated with production of {sup 177}Lu for use in targeted radionuclide therapy (TRT) dictate that a holistic consideration should evaluate all governing factors that determine its success. While both “direct” and “indirect” reactor production routes offer the possibility for sustainable {sup 177}Lu availability, there are several issues and challenges that must be considered to realize the full potential of these production strategies. This article presents a mini review on the latest developments, current status, key challenges and possibilities for the near future. A broad understanding and discussion of the issues associated with {sup 177}Lu production and processing approaches would not only ensure sustained growth and future expansion for the availability and use of {sup 177}Lu-labeled radiopharmaceuticals, but also help future developments.

  15. Adsorption Behavior and Mechanism of Macroporous Phosphonic Acid Resin for Lu3+

    Institute of Scientific and Technical Information of China (English)

    WANG Hui-jun; XIONG Chun-hua

    2006-01-01

    The article is based on a research on the adsorption behavior and adsorption mechanism of macroporous phosphonic acid resin (PAR) for Lu3+ and the influence of the medium's pH, adsorption temperature, adsorption time, etc on adsorbing Lu3 + . The best value of medium's pH to the adsorption of PAR for Lu3 + was found to be 4.92. The static adsorption maximum capacity of PAR for Lu3 + is 220 mg· g-1. The thermodynamic adsorption parameters are respectively △H= 11.3 kJ·mol-1, △S =46.3 J·mol-1 ·K-1, △G = - 2.50 kJ·mol-1 and the apparent activity energy is Ea= 31.4 kJ· mol- 1. The adsorption behavior of PAR for Lu3 + obeys the Freundlich isotherm. The apparent adsorption rate constant is k298 = 4.68 × 10-5 s-1. The coordinate ratio of the functional radical to Lu3 + is approximately 4: 1. The best eluant is 1.0 mol· L- 1 HCl. The adsorption mechanism of PAR for Lu3 + was separately confirmed by chemical analysis and IR spectra.

  16. Co-precipitation synthesis of lutetium aluminum garnet (LuAG) powders: The influence of ethanol

    Science.gov (United States)

    Pan, Liangjie; Jiang, Benxue; Fan, Jintai; Zhang, Pande; Mao, Xiaojian; Zhang, Long

    2017-09-01

    Aluminum Garnet (LuAG) precursors were co-precipitated by using ethanol-water as the precipitant solvent. The effect of different volume ratios of ethanol to water (R) on the preparation of pure-phase LuAG powders has been mainly studied. The evolution of phase, composition and micro-structure of the as-synthesized LuAG powders were characterized by TG/DTA, FTIR, XRD, BET, and SEM. The BET-equivalent diameter of LuAG nano particles increased with R. The ethanol-water solvent does not change the main composition of the LuAG precursors, but has great influence on the morphology of the final LuAG nano particles. Uniformly dispersed LuAG powders calcined at 1200 °C for 3 h with a particle size of approximately 120 nm were obtained by using ethanol-water solvent with proper R = 1. The mechanism of ethanol in the preparation process was discussed.

  17. Multiferroic behavior in Lu2MnCoO6

    Science.gov (United States)

    Zapf, Vivien; Mun, E.-D.; Ueland, B. G.; Thompson, J. D.; Singleton, J.; Gardner, J.; Yáñez-Vilar, S.; Sánchez-Anduacute; jar; , M.; Señaris-Rodriguez, M. A.; Mira, J.; Biskup, N.; Batista, C. D.

    2012-02-01

    Lu2MnCoO6 is a new member of the multiferroics with coupling between net magnetization and net electric polarization. Similar to Ca3MnCoO6, an up-up-down-down order of the magnetic spins is found that breaks spatial-inversion symmetry and creates an electric polarization. Unlike Ca3MnCoO6, the Co and Mn ions are both in a S = 3/2 state, the ordering temperature is 42 K, and the magnetic field needed to suppress electric polarization is 2 T. We present an experimental study of the multiferroic properties and spin structure including neutron diffraction, electric polarization, magnetization, dielectric constant, and specific heat measurements.

  18. Coexisting normal and triaxial superdeformed structures in {sup 165}Lu

    Energy Technology Data Exchange (ETDEWEB)

    Schoenwasser, G.; Nenoff, N.; Huebel, H. E-mail: hubel@iskp.uni-bonn.de; Hagemann, G.B.; Bednarczyk, P.; Benzoni, G.; Bracco, A.; Bringel, P.; Chapman, R.; Curien, D.; Domscheit, J.; Herskind, B.; Jensen, D.R.; Leoni, S.; Lo Bianco, G.; Ma, W.C.; Maj, A.; Neusser, A.; Oedegaard, S.W.; Petrache, C.M.; Rossbach, D.; Ryde, H.; Singh, A.K.; Spohr, K.H

    2004-05-03

    High-spin states in {sup 165}Lu were populated in the {sup 139}La({sup 30}Si,4n) reaction at a beam energy of 152 MeV and {gamma}-ray coincidences were measured with the EUROBALL spectrometer array. Nine new rotational bands were discovered, known band structures were considerably extended and many inter-band transitions were found. Structures with normal deformation coexist with bands associated with the strongly deformed triaxial energy minima found in calculations. Three of these triaxial bands form a family of wobbling excitations with phonon quanta n{sub w}=0, 1 and 2. The wobbling mode is a unique signature of nuclear triaxiality. Configuration assignments are discussed for the observed band structures. An exchange of configuration between two of the new bands due to mixing is observed, resulting in different signature partnerships at low and high spins.

  19. Innovative LuYAP:Ce array for PET imaging

    Science.gov (United States)

    Cinti, M. N.; Scafe, R.; Bennati, P.; Lo Meo, S.; Frantellizzi, V.; Pellegrini, R.; De Vincentis, G.; Sacco, D.; Fabbri, A.; Pani, R.

    2017-03-01

    We present an imaging characterization of a 10 × 10 LuYAP array (2 × 2 × 10 mm3 pixels) with an innovative dielectric coating insulation (0.015 mm thick), in view of its possible use in a gamma camera for imaging positron emission tomography (PET) or in similar applications, e.g. as γ -prompt detector in hadron therapy. The particular assembly of this array was realized in order to obtain a packing fraction of 98%, improving detection efficiency and light collection. For imaging purpose, the array has been coupled with a selected Hamamatsu H10966-100 Multi Anode Photomultiplier read out by a customized 64 independent channels electronics. This tube presents a superbialkali photocathode with 38% of quantum efficiency, permitting to enhance energy resolution and consequently image quality. A pixel identification of about 0.5 mm at 662 keV was obtained, highlighting the potentiality of this detector in PET applications.

  20. Influence of Eu(3+) doping content on antioxidant properties of Lu2O3 sol-gel derived nanoparticles.

    Science.gov (United States)

    Olvera Salazar, Arturo; García Hernández, Margarita; López Camacho, Perla Yolanda; López Marure, Arturo; Reyes de la Torre, Adriana Isabel; Morales Ramírez, Ángel de Jesús; Hernández Santiago, Felipe; Aguilera Vázquez, Luciano

    2016-12-01

    This paper presents the synthesis of pure and europium-doped lutetium oxide (Lu2O3) powders prepared by sol-gel method. The influence of europium ion concentration into Lu2O3 nanocrystallites was investigated for first time in an in vitro system using a modified ABTS radical cation decolorization assay to determine the antioxidant activity. The crystalline structure of Lu2O3 and Eu:Lu2O3 powders was elucidated by XRD obtaining cubic phase in all system without secondary products in accordance with FT-IR results. By TEM and Scherrer equation, it was determined that Lu2O3 and Eu:Lu2O3 powders presented nearly spherical particle morphology with crystallites sizes in the range of 8 to 13nm. The antioxidant assays results revealed that europium ion enhance Lu2O3 powders antioxidant properties, showing that 12.5mol% of europium is sufficient to reach its maximum capacity.

  1. [{sup 177}Lu]DOTA-anti-CD20: Labeling and pre-clinical studies

    Energy Technology Data Exchange (ETDEWEB)

    Audicio, Paola F., E-mail: paudicio@cin.edu.u [Departamento de Radiofarmacia, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la Republica, Mataojo 2055, 11400 Montevideo (Uruguay); Castellano, Gustavo, E-mail: gcas@famaf.unc.edu.a [FaMAF, Universidad Nacional de Cordoba, Ciudad Universitaria, 5016 Cordoba (Argentina); Tassano, Marcos R.; Rezzano, Maria E.; Fernandez, Marcelo [Departamento de Radiofarmacia, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la Republica, Mataojo 2055, 11400 Montevideo (Uruguay); Riva, Eloisa [Clinica Hematologica ' Prof. Dra. L. Diaz' , Hospital de Clinicas. Av. Italia. sn, Montevideo (Uruguay); Robles, Ana; Cabral, Pablo; Balter, Henia; Oliver, Patricia [Departamento de Radiofarmacia, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la Republica, Mataojo 2055, 11400 Montevideo (Uruguay)

    2011-07-15

    Anti-CD20 (Rituximab), a specific chimeric monoclonal antibody used in CD20-positive Non-Hodgkin's Lymphoma, was conjugated to a bifunctional quelate (DOTA) and radiolabeled with {sup 177}Lu through a simple method. [{sup 177}Lu]-DOTA-anti-CD20 was obtained with a radiochemical purity higher than 97%, and showed good chemical and biological stability, maintaining its biospecificity to CD20 antigens. Monte Carlo simulation showed high doses deposited on a spheroid tumor mass model. This method seems to be an appropriate alternative for the production of [{sup 177}Lu]-DOTA-anti-CD20 as therapeutic radiopharmaceutical.

  2. Predicting the yield of {sup 177}Lu radionuclide produced by the cyclic irradiation technique

    Energy Technology Data Exchange (ETDEWEB)

    Odame Duodu, Godfred, E-mail: jogd14@yahoo.co [Radiological and Medical Sciences Research Institute, Ghana Atomic Energy Commission, P.O. Box LG80, Legon Accra (Ghana); Akaho, Edward H.K.; Serfor-Armah, Yaw [Ghana Atomic Energy Commission, P.O. Box LG80, Legon Accra (Ghana); Nyarko, Benjamin J.B. [National Nuclear Research Institute, Ghana Atomic Energy Commission, P.O. Box LG80, Legon Accra (Ghana); Afi Achoribo, Elom [Radiological and Medical Sciences Research Institute, Ghana Atomic Energy Commission, P.O. Box LG80, Legon Accra (Ghana)

    2011-03-15

    The feasibility study on the production of {sup 177}Lu radioisotope using a low power research reactor has been conducted. A reliable method for predicting the yield of {sup 177}Lu produced using the cyclic activation technique based on the Westcott formalism has been established. A specific activity of 243.24 mCi/g was obtained when a {sup 176}Lu{sub 2}O{sub 3} of natural abundance was irradiated for 4 h and decayed for 20 h for four cycles at GHARR-1 with a neutron flux of 5.0x10{sup 11} ncm{sup -2} s{sup -1}.

  3. Lu-hf total-rock isochron for the eucrite meteorites

    Science.gov (United States)

    Patchett, P.J.; Tatsumoto, M.

    1980-01-01

    The isotope 176Lu (2.6% of natural lutetium) decays by ??- to 176Hf, with a long half life. We present here the first Lu-Hf isochron. The eucrite meteorites, a suite of planetary igneous rocks of known age, 4,550 Myr, define a 10-point total-rock isochron with a slope of 0.0934 ?? 40, leading to a value of 3.53 ?? 0.14 ??1010yr for the ??--decay half life of 176Lu. The isochron intercept of 0.27973 ?? 12 gives the initial 176Hf/177Hf for the inner Solar System at the time of accretion. ?? 1980 Nature Publishing Group.

  4. 高敬亭案件深度剖析%Deep Analysis on the Case of Gao Jing -ting

    Institute of Scientific and Technical Information of China (English)

    童志强

    2015-01-01

    1939年6月被处死的新四军第4支队司令员高敬亭确实犯有严重错误,高案的发生有一个渐变的过程。新四军军长叶挺不应对高案负主要责任。高案的处理决定,是在矛盾激化之后,最终由中共中央拍板的。其中,皖南项英是遥控者,江北叶挺、张云逸、邓子恢等人是执行者,延安党中央是最后决断者。重庆蒋介石“所请将高敬亭处以枪刑照准”不过是顺水推舟,乐见其成罢了。%Gao Jing -ting,the commanding officer of the fourth detachment of the N4A,who was executed in June 1939, did make big mistakes.But his death is the result of a gradual process.Ye Ting,commander of the N4A,should not be pri-marily responsible for this case.Gao Jing -ting’s death sentence was decided by the Central Committee of the Chinese Com-munist Party after the conflict became acute.In this case,Xiang Ying,who was in southern Anhui,played the role of remote control;Ye Ting,Zhang Yun -yi and Deng Zi -hui,who were in north of the Chang Jiang River ,played the role of the ex-ecutor;the Central Committee of the Chinese Communist Party in Yan’an,played the role of the final decider.Chiang Kai -shek’s approval of the death sentence was just an action of pushing the boat with the current.

  5. Gao is the Protective Layer of Organs in Huangdi Neijing%《内经》的“膏”是指以脂肪为主要结构成分的一类实体

    Institute of Scientific and Technical Information of China (English)

    周波; 欧武

    2012-01-01

    By exploring the anatomy of Gao Source and Huang Source in Huangdi Neijing, Gao refers to fat as the main component of a class of entities, including at least the Apical of the fat and Omentum. Gao in disease entering Gaohuang is the Apical of the fat; Gao in Gao Source is the omentum. Ventral midline of the lower edge of the right lohe and the stomach along the greater curvature of the bottom, it is the anatomical location for Gao Source , and Jiuwei point is along the central line in this.%通过探讨《内经》“肓之原”和“膏之原”的解剖结构,认为《内经》的“膏”是指以脂肪为主要成分的一类实体,其中至少包括了心尖部脂肪和大网膜.“病入膏肓”和“膏之原”中,二者中“膏”的解剖实体,分别指的是心尖部脂肪和大网膜;“膏之原”的解剖位置是腹正中线的肝右叶下缘和胃大弯的沿线之下;“鸠尾穴”位于这条沿线的中央.

  6. A Brief Report of the Excavation of Gao Lishi's Tomb of Tang Dynasty%唐高力士墓发掘简报

    Institute of Scientific and Technical Information of China (English)

    陕西省考古研究所

    2002-01-01

    Gao Lishi is the most celeberated eunuch in China's history. He served the emperor Tang Xuan zong(Li longji) all his life, and gained almost the first rank official position.At 762 A.D.,he was died in his 73, and was buried near the emperor's mausoleum named Tai Ling next year, which located at Shanxi village, Pucheng county. The tomb composed of a vamp, four narrow patios-like spaces, three passages, six niches, a brick corridor and tomb chamber, simple murals were painted on the both side of the ramp, the corridor and the chamber wall, but most of them were destroyed. Fancy patterns were carved on the surfuces of the stone tomb-gate and the stone coffin bed. More than two handred pottery statues were found in the miches, including housemen, servants and animals such as horses, pigs, camels, dogs, rabbits and so on. Some bones found in the coffin bed have been authenticated that belong to a man older than sixty. It is unusaal that the epitaph stone is vectangular. The epitaph narrated Gao's original name, ancestry, feats, official positions and his fanmily,ect. Excavation of this tomb provide valuable date for the research of Tang dynasty history, and we can see that Gao Lishi was down and out at his death from the tomb structure and the relics.

  7. 高镜朗:中国儿科泰斗%Gao Jinglang: the Great Master of Chinese Pediatrics

    Institute of Scientific and Technical Information of China (English)

    陈挥; 宋霁

    2012-01-01

    以档案资料和历史文献为基础,记述中国儿科大家高镜朗的医学人生,并通过梳理和总结他的学术成长经历,展现其行医济世、以医强国的人生追求与抱负,进而从临床治疗、科学研究、人才培养和学科建设等四个方面,阐述他为新中国儿科医学事业的创设和发展做出的巨大贡献.%Based on the archives and historical literature, narrated the medical career of Mr. Gao Jinglang who was the great master of Chinese pediatrics. By the analysis and summary of his academic experience, it showed his pursuit and ambition to practicing medicine to save people and make China stronger. Then discussed his contribution to the foundation and development of Chinese pediatrics from four aspects: clinical care, academic research, medical education and subject development.

  8. ‘Deconstructing Gao Minglu: critical reflections on contemporaneity and associated exceptionalist readings of contemporary Chinese art’

    Directory of Open Access Journals (Sweden)

    Paul Gladston

    2014-06-01

    Full Text Available In this article, I shall seek to offer an ethically/politically focused critique of exceptionalist accounts of the development of contemporary Chinese art. I shall begin by giving a brief overview of thinking associated with the concept of contemporaneity. I shall then go on to analyze critically an essay by the historian and curator Gao Minglu, which asserts that contemporary Chinese art is open to localized Chinese interpretative perspectives separate from those of internationally dominant postmodernist discourses. In analyzing Gao’s essay, I shall not only argue that its exceptionalist account of the significance of contemporary Chinese art relies on highly selective readings of historical ‘fact’, but also that it is theoretically contradictory/inconsistent and therefore unsustainable as a categorical truth claim. I shall then conclude by examining the ethical/political implications of Gao’s exceptionalist account of the significance of contemporary Chinese art as well as advancing some first thoughts towards a general critique of contemporaneity.

  9. Gao Gong "Retaliation" Question Discrimination——Since by Wang Shizhen "Jiajing auxiliary biography Gao Gong Biography" is a center%丑诋与厚诬:高拱“报复”问题辨析——以王世贞《嘉靖以来首辅传·高拱传》为中心

    Institute of Scientific and Technical Information of China (English)

    岳天雷

    2011-01-01

    明代嘉、隆时期政治家和改革家高拱的"报复"问题,可谓由来已久。追根溯源,这一问题盖出自王世贞《嘉靖以来首辅传》之《高拱传》。该传作为高拱逝世后最早的一篇传记,多半篇幅叙述他倾轧同僚,报复朝官,排斥异己,贪赃纳贿等,从而使高拱背负"报复"恶名,并对其后史家修撰的多篇《高拱传》及其现今史学界也产生了严重负面影响。澄清这一问题,对如实评价高拱的政治品格和道德操守具有重要意义。%The Ming Dynasty statesman and the reformer Gao Gong "the retaliation" the question,as if has become the conclusion in the history educational world,however this does not tally with the historical fact.Gets to the bottom,since this question has stemmed from Wang Shizhen most early "Jiajing an Auxiliary Biography""Gao Gong Biography".Not only,therefore should the biography cause Gao Gong to shoulder repairs resentful,nurses a grudge "the retaliation" the evil reputation,moreover many which composes to the Ming and Qing Dynasties historian "Gao Gong Biography" and the nowadays history educational world has had the serious negative influence.Discriminates this question,is helpful in makes to Gao Gong political moral character and the moral personal integrity conforms to the historical evidence appraisal.

  10. Langston University - High Energy Physics (LU-HEP)

    Energy Technology Data Exchange (ETDEWEB)

    Snow, Dr., Joel [Langston Univ., OK (United States)

    2012-08-13

    This final report is presented by Langston University (LU) for the project entitled "Langston University High Energy Physics" (LUHEP) under the direction of principal investigator (PI) and project director Professor Joel Snow. The project encompassed high energy physics research performed at hadron colliders. The PI is a collaborator on the DZero experiment at Fermi National Accelerator Laboratory in Batavia, IL, USA and the ATLAS experiment at CERN in Geneva, Switzerland and was during the entire project period from April 1, 1999 until May 14, 2012. Both experiments seek to understand the fundamental constituents of the physical universe and the forces that govern their interactions. In 1999 as member of the Online Systems group for Run 2 the PI developed a cross-platform Python-based, Graphical User Interface (GUI) application for monitoring and control of EPICS based devices for control room use. This served as a model for other developers to enhance and build on for further monitoring and control tasks written in Python. Subsequently the PI created and developed a cross-platform C++ GUI utilizing a networked client-server paradigm and based on ROOT, the object oriented analysis framework from CERN. The GUI served as a user interface to the Examine tasks running in the D\\O\\ control room which monitored the status and integrity of data taking for Run 2. The PI developed the histogram server/control interface to the GUI client for the EXAMINE processes. The histogram server was built from the ROOT framework and was integrated into the D\\O\\ framework used for online monitoring programs and offline analysis. The PI developed the first implementation of displaying histograms dynamically generated by ROOT in a Web Browser. The PI's work resulted in several talks and papers at international conferences and workshops. The PI established computing software infrastructure at LU and U. Oklahoma (OU) to do analysis of DZero production data and produce simulation

  11. Influence of magnetic on ferroelectric ordering in LuMnO3

    Science.gov (United States)

    van Aken, Bas B.; Palstra, Thomas T.

    2004-04-01

    We have studied the influence of antiferromagnetic ordering on the local dielectric moments of the MnO5 and LuO7 polyhedra by measuring neutron powder-diffraction patterns of LuMnO3 at temperatures near TN. We show that the coupling is weak, because the magnetic exchange coupling is predominantly in the ab plane of the MnO5 trigonal bipyramids, and the electric dipole moments, originating in the LuO7 polyhedra, are oriented along the hexagonal c axis. Anomalies in the dielectric properties near TN are thus caused by the geometric constraints between the MnO5 and the LuO7 polyhedra.

  12. Algorithms for numerical and symbolic analysis of linear circuits and methods of derivatives LU-decomposition

    Directory of Open Access Journals (Sweden)

    V. A. Golovin

    1986-04-01

    Full Text Available The algorithms of numerical and symbolic analysis methods of linear chains of derivatives and LU-decomposition. An example of the calculation circuit functions using programs that implement the proposed algorithms.

  13. Intrinsic magnetic properties of hexagonal LuFeO3 and the effects of nonstoichiometry

    Directory of Open Access Journals (Sweden)

    Jarrett A. Moyer

    2014-01-01

    Full Text Available We used oxide molecular-beam epitaxy in a composition-spread geometry to deposit hexagonal LuFeO3 (h-LuFeO3 thin films with a monotonic variation in the Lu/Fe cation ratio, creating a mosaic of samples that ranged from iron rich to lutetium rich. We characterized the effects of composition variation with x-ray diffraction, atomic force microscopy, scanning transmission electron microscopy, and superconducting quantum interference device magnetometry. After identifying growth conditions leading to stoichiometric film growth, an additional sample was grown with a rotating sample stage. From this stoichiometric sample, we determined stoichiometric h-LuFeO3 to have a TN = 147 K and Ms = 0.018 μB/Fe.

  14. Predictor-Corrector LU-SGS Discontinuous Galerkin Finite Element Method for Conservation Laws

    National Research Council Canada - National Science Library

    Ma, Xinrong; Liu, Sanyang; Xie, Gongnan

    2015-01-01

      Efficient implicit predictor-corrector LU-SGS discontinuous Galerkin (DG) approach for compressible Euler equations on unstructured grids is investigated by adding the error compensation of high-order term...

  15. lu ja liikumine kui ruumipraktikad = Memory and motion as spatial practices / Morten Lund

    Index Scriptorium Estoniae

    Lund, Morten, 1972-

    2015-01-01

    Artiklis on käsitletud nelja uurimust ruumist, mis illustreerivad võimalusi, kuidas sisearhitektuur võib kaasata mälu ja liikumise kui ruumilised praktikad läbi ruumilise kunsti ning 1:1 eksperimentide

  16. Gamma radiation exposure of accompanying persons due to Lu-177 patients

    Directory of Open Access Journals (Sweden)

    Kovan Bilal

    2015-01-01

    Full Text Available Neuroendocrine tumours (NET are cancers usually observed and arisen in the stomach, intestine, pancreas and breathing system. Recently, radionuclide therapy applications with Lu-177 peptide compound are rapidly growing; especially effective clinical results are obtained in the treatment of well-differentiated and metastatic NET. In this treatment, Lu-177-DOTA, a beta emitter radioisotope in the radiopharmaceutical form, is given to the patient by intravenous way. Lu-177 has also gamma rays apart from beta rays. Gamma rays have 175 keV average energy and these gamma rays should be under the control in terms of radiation protection. In this study, we measured the exposure dose from the Lu-177 patient.

  17. lu ja liikumine kui ruumipraktikad = Memory and motion as spatial practices / Morten Lund

    Index Scriptorium Estoniae

    Lund, Morten, 1972-

    2015-01-01

    Artiklis on käsitletud nelja uurimust ruumist, mis illustreerivad võimalusi, kuidas sisearhitektuur võib kaasata mälu ja liikumise kui ruumilised praktikad läbi ruumilise kunsti ning 1:1 eksperimentide

  18. Intrinsic magnetic properties of hexagonal LuFeO{sub 3} and the effects of nonstoichiometry

    Energy Technology Data Exchange (ETDEWEB)

    Moyer, Jarrett A., E-mail: moyerja@illinois.edu, E-mail: schlom@cornell.edu; Schiffer, Peter [Department of Physics and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801 (United States); Misra, Rajiv [Department of Physics, Pennsylvania State University, University Park, Pennsylvania 16802 (United States); Mundy, Julia A. [School of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853 (United States); Brooks, Charles M.; Heron, John T. [Department of Materials Science and Engineering, Cornell University, Ithaca, New York 14853 (United States); Muller, David A. [School of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853 (United States); Kavli Institute at Cornell for Nanoscale Science, Ithaca, New York 14853 (United States); Schlom, Darrell G., E-mail: moyerja@illinois.edu, E-mail: schlom@cornell.edu [Department of Materials Science and Engineering, Cornell University, Ithaca, New York 14853 (United States); Kavli Institute at Cornell for Nanoscale Science, Ithaca, New York 14853 (United States)

    2014-01-01

    We used oxide molecular-beam epitaxy in a composition-spread geometry to deposit hexagonal LuFeO{sub 3} (h-LuFeO{sub 3}) thin films with a monotonic variation in the Lu/Fe cation ratio, creating a mosaic of samples that ranged from iron rich to lutetium rich. We characterized the effects of composition variation with x-ray diffraction, atomic force microscopy, scanning transmission electron microscopy, and superconducting quantum interference device magnetometry. After identifying growth conditions leading to stoichiometric film growth, an additional sample was grown with a rotating sample stage. From this stoichiometric sample, we determined stoichiometric h-LuFeO{sub 3} to have a T{sub N} = 147 K and M{sub s} = 0.018 μ{sub B}/Fe.

  19. Multimodal Somatostatin Receptor Theranostics Using [64Cu]Cu-/[177Lu]Lu-DOTA-(Tyr3)octreotate and AN-238 in a Mouse Pheochromocytoma Model

    Science.gov (United States)

    Ullrich, Martin; Bergmann, Ralf; Peitzsch, Mirko; Zenker, Erik F.; Cartellieri, Marc; Bachmann, Michael; Ehrhart-Bornstein, Monika; Block, Norman L.; Schally, Andrew V.; Eisenhofer, Graeme; Bornstein, Stefan R.; Pietzsch, Jens; Ziegler, Christian G.

    2016-01-01

    Pheochromocytomas and extra-adrenal paragangliomas (PHEO/PGLs) are rare catecholamine-producing chromaffin cell tumors. For metastatic disease, no effective therapy is available. Overexpression of somatostatin type 2 receptors (SSTR2) in PHEO/PGLs promotes interest in applying therapies using somatostatin analogs linked to radionuclides and/or cytotoxic compounds, such as [177Lu]Lu-DOTA-(Tyr3)octreotate (DOTATATE) and AN-238. Systematic evaluation of such therapies for the treatment of PHEO/PGLs requires sophisticated animal models. In this study, the mouse pheochromocytoma (MPC)-mCherry allograft model showed high tumor densities of murine SSTR2 (mSSTR2) and high tumor uptake of [64Cu]Cu-DOTATATE. Using tumor sections, we assessed mSSTR2-specific binding of DOTATATE, AN-238, and somatostatin-14. Therapeutic studies showed substantial reduction of tumor growth and tumor-related renal monoamine excretion in tumor-bearing mice after treatment with [177Lu]Lu-DOTATATE compared to AN-238 and doxorubicin. Analyses did not show agonist-dependent receptor downregulation after single mSSTR2-targeting therapies. This study demonstrates that the MPC-mCherry model is a uniquely powerful tool for the preclinical evaluation of SSTR2-targeting theranostic applications in vivo. Our findings highlight the therapeutic potential of somatostatin analogs, especially of [177Lu]Lu-DOTATATE, for the treatment of metastatic PHEO/PGLs. Repeated treatment cycles, fractionated combinations of SSTR2-targeting radionuclide and cytotoxic therapies, and other adjuvant compounds addressing additional mechanisms may further enhance therapeutic outcome. PMID:27022413

  20. The Significance of Symbolic Elements in Lu Xun’s Short Stories

    Directory of Open Access Journals (Sweden)

    Tina Ilgo

    2010-12-01

    Full Text Available The present article interprets the symbolic elements in Lu Xun’s short stories which have been neglected in earlier studies about Lu Xun. I intend to show that the most obvious symbols in his fiction, like the iron room, the cannibalism, etc., have their counter balance in the animal symbols present in his work. Following this idea, I will focus on his less famous stories, such as A Comedy of Ducks and Some Rabbits and a Cat.

  1. High-light-output scintillator for photodiode readout: LuI3:Ce3+

    NARCIS (Netherlands)

    Birowosuto, M.D.; Dorenbos, P.; Van Eijk, C.W.E.; Krämer, K.W.; Güdel, H.U.

    2006-01-01

    In this paper, we investigated the scintillation properties of LuI3:Ce3+. Radioluminescence, light output, energy resolution, and γ-scintillation decay are reported. We find an extremely high light output of 98 000±10 000 photons/MeV. LuI3:Ce3+ also gives a very high electron-hole (e-h) pair respons

  2. In Vivo Measurement and Characterization of a Novel Formulation of [177Lu]-DOTA-Octreotate

    Directory of Open Access Journals (Sweden)

    Dale Bailey

    2016-01-01

    Full Text Available Objective(s:Lutetium-177 can be made with high specific activity and with no other isotopes of lutetium present, referred to as “No Carrier Added” (NCA 177Lu. We have radiolabelled DOTA-conjugated peptide DOTA‐(Tyr3‐octreotate with NCA 177Lu (“NCA-LuTATE” and used it in nearly 40 therapeutic administrations for subjects with neuroendocrine tumours or meningiomas. In this paper, we report on our initial studies on aspects of the biodistribution and dosimetry of NCA-LuTATE from gamma camera 2D whole body (WB and quantitative 3D SPECT (qSPECT 177Lu imaging. Methods: Thirteen patients received 39 NCA-LuTATE injections. Extensive WB planar and qSPECT imaging was acquired at approximately 0.5, 4, 24 and 96 h to permit estimates of clearance and radiation dose estimation using MIRD-based methodology (OLINDA-EXM. Results:The average amount of NCA-Lutate administered per cycle was 7839±520 MBq. Bi-exponential modelling of whole body clearance showed half lives for the fast & slow components of t½=2.1±0.6 h and t½=58.1±6.6 h respectively. The average effective dose to kidneys was 3.1±1.0 Gy per cycle. In eight patients completing all treatment cycles the average total dose to kidneys was 11.7±3.6 Gy. Conclusions: We have shown that NCA-LuTATE has an acceptable radiation safety profile and is a suitable alternative to Carrier-Added 177Lu formulations. The fast component of the radiopharmaceutical clearance was closely correlated with baseline renal glomerular filtration rate, and this had an impact on radiation dose to the kidneys. In addition, it has less radioactive waste issues and requires less peptide per treatment.

  3. Progress in the development of LuAlO$_{3}$ based scintillators

    CERN Document Server

    Belsky, A; Lecoq, P; Dujardin, C; Garnier, N; Canibano, H; Pédrini, C; Petrosian, A

    2000-01-01

    LuAlO/sub 3/:Ce/sup 3+/ (LuAP) and Lu/sub x/Y/sub 1/-xAlO/sub 3/:Ce /sup 3+/ (LuYAP) crystals are used as scintillation materials for positron emission tomography. The actual study of these scintillators develops in three directions: (i) growth of large size LuAP crystals with stable properties, (ii) the relationship between the composition of LuYAP crystals and scintillation properties, and (iii) scintillation mechanisms in lutetium compounds. After improving of growth conditions a large size samples (length >40 mm) have been prepared. Crystals show a good correlation between growth parameters, light yield and transmission spectra. We studied a series of samples with calibrated size (2*2*10 mm3) and compare the light yield with standard BGO and LSO samples. Mixed crystals with composition of 0.6

  4. Overview of Development and Formulation of ¹⁷⁷Lu-DOTA-TATE for PRRT.

    Science.gov (United States)

    Breeman, Wouter A P; Chan, Ho Sze; de Zanger, Rory M S; Konijnenberg, Mark K; de Blois, Erik

    2016-01-01

    Peptide receptor radionuclide therapy (PRRT) using radiolabeled somatostatin analogs has become an established procedure for the treatment of patients suffering from inoperable neuroendocrine cancers over-expressing somatostatin receptors. Success of PRRT depends on the availability of the radiolabeled peptide with adequately high specific activity, so that required therapeutic efficacy can be achieved without saturating the limited number of receptors available on the target lesions. Specific activity of the radionuclide and the radiolabeled somatostatin analog are therefore an important parameters. Although these analogs have been investigated and improved, and successfully applied for PRRT for more than 15 years, there are still many possibilities for further improvements that fully exploit PRRT with 177Lu-DOTA-TATE. The here summarized data presented herein on increased knowledge of the components of 177Lu-DOTA-TATE (especially the purity of 177Lu and specific activity of 177Lu) and the reaction kinetics during labeling 177Lu-DOTA-TATE clearly show that the peptide dose and dose in GBq can be varied. Here we present an overview of the development, formulation and optimisation of 177Lu-DOTA-TATE, mainly addressing radiochemical parameters.

  5. Correlation between magnon and magnetic symmetries of hexagonal RMnO3 (R = Er, Ho, Lu)

    Science.gov (United States)

    Nguyen, Thi Minh Hien; Nguyen, Thi Huyen; Chen, Xiang-Bai; Park, Yeonju; Jung, Young Mee; Lee, D.; Noh, T. W.; Cheong, Sang-Wook; Yang, In-Sang

    2016-11-01

    The correlation between the magnon scattering and the magnetic symmetries of hexagonal RMnO3 (R = Er, Ho) thin films and LuMnO3 single crystal was studied through the 2D Correlation Spectroscopy (2D COS) and Perturbation-Correlation Moving Window 2D (PCMW2D) Correlation Spectroscopy which were performed on the temperature-dependent Raman spectra of RMnO3 (R = Er, Ho, Lu). From the Raman spectra, we observed much stronger intensity and more asymmetrical magnon peak in LuMnO3 single crystal than in ErMnO3 and HoMnO3 thin films. While the ratio between magnon and phonon's linewidth of LuMnO3 and HoMnO3 display an anomalous behavior, that ratio of ErMnO3 is almost stable. The result from PCMW2D also supports these results. In addition, our 2D COS analysis showed that there are more overlap peaks in broad four-spin flipping magnon peak in LuMnO3 than that in ErMnO3 and HoMnO3. The differences of hexagonal RMnO3 (R = Er, Ho, Lu) in magnon scattering are very similar to the actual differences of the magnetic symmetries of these compounds. Therefore, we suggest that the magnon scattering of hexagonal RMnO3 is strongly correlated with the magnetic symmetries of these materials.

  6. Lu-Hf and Sm-Nd garnet geochronology

    DEFF Research Database (Denmark)

    Smit, Matthijs Arjen; Scherer, Erik E.; Mezger, Klaus

    2013-01-01

    are similar among grains having radii larger than 1.3 mm (weighted mean: 2714±6 Ma2714±6 Ma; 2 s.d.) and up to 20 Myr younger for finer fractions. In contrast, Sm–Nd dates are equal to or younger than the 2641–2637 Ma age of peak metamorphism. The roles of concurrently digested inclusions and core–rim Lu......To investigate the systematics of the 176Lu–176Hf and 147Sm–143Nd garnet chronometers, we performed REE and isotope analyses on garnet crystals of different size (0.55–3.1 mm radius) from a single granulite specimen (Archean Pikwitonei Granulite Domain, Manitoba, Canada). The Lu–Hf dates....../Sm fractionation are quantitatively evaluated and excluded as causes for the observed age heterogeneity. Instead, the isotope dates are interpreted to reflect partial loss of radiogenic 176Hf and 143Nd, and are used to constrain the systematics of the garnet chronometers at high temperature. The data constrain...

  7. A Stalwart Fighter for New China All Her Life——In Memory of Comrade Lu Cui

    Institute of Scientific and Technical Information of China (English)

    Shu; Zhang

    2015-01-01

    The Spring Festival had just ended when I received a phone call from Lu Lanqin to tell me that her mother had passed away.I was saddened by this sudden news,even though she had lived a remarkable 101 years.And she will always live in our hearts.The mother of Lu Lanqin was our beloved Comrade Lu Cui,an outstanding woman who worked hard for New

  8. Problematika zvyšování podílu R - materiálu v asfaltových směsích

    OpenAIRE

    Urbanec, Luboš

    2013-01-01

    Předmětem této diplomové práce je problematika asfaltových směsí se zvyšujícím se podílem R-materiálu. V teoretické části práce jsou definovány pojmy recyklace a R-materiál a popsány druhy recyklace. Praktická část se věnuje výrobě a zkoušení asfaltových směsí s různým obsahem R-materiálu. Navrhovaná asfaltová směs je asfaltový beton pro podkladní vrstvy ACP22+. Obsah R-materiálu ve směsích je 0%, 30%, 50% a 70%. Jako speciální přísada pro změkčení asfaltu z R-materiálu se používá přísada STO...

  9. A potencial theranostic agent for EGF-R expression tumors: (177)Lu-DOTA-nimotuzumab.

    Science.gov (United States)

    Calzada, Victoria; Zhang, Xiuli; Fernandez, Marcelo; Diaz-Miqueli, Arlhee; Iznaga-Escobar, Normando; Deutscher, Susan L; Balter, Henia; Quinn, Thomas P; Cabral, Pablo

    2012-10-01

    In this work Nimotuzumab (monoclonal antibody, recognizes the EGF-R) was radiolabeled with (177)Lu as a potential cancer therapy radiopharmaceutical. In-vitro cell binding studies and in-vivo biodistribution and imaging studies were performed to determine the radiochemical stability, targeting specificity and pharmacokinetics of the (177)Lu-labeled antibody. Nimotuzumab was derivatized with DOTA-NHS at room temperature for 2 hours. DOTA-Nimotuzumab was radiolabeled with (177)LuCl3 (15 MBq/mg) at 37°C for 1 h. The radiochemical purity was assessed by ITLC, silica gel and by RP-HPLC. Binding specificity studies were performed with EGF-R positive A431 human epithelial carcinoma and EGF-R negative MDA-MB-435 breast carcinoma cells. Biodistribution studies were performed in healthy female CD-1 mice at 1 h, 4 h, 24 h, and A431 xenografted nude mice at 10 min, 1 h, 4 h, 24 h, 48 h, and 96 h. SPECT-CT imaging studies were performed in A431 xenografted mice at 24 h post injection. DOTA-Nimotuzumab was efficiently labeled with (177) LuCl(3) at 37°C. The in vitro stability of labeled product was optimal over 24 h in buffered saline and mouse serum. Specific recognition of EGF-R by (177)Lu-DOTA-Nimotuzumab was observed in A431 cell binding studies. Biodistribution studies demonstrated increasing tumor uptake of (177)Lu-DOTA-Nimotuzumab over time, with tumor to muscle ratios of 6.26, 10.68, and 18.82 at 4 h, 24 h, and 96 h post injection. Imaging of A431 xenografted mice showed high uptake in the tumor. (177)Lu-DOTA-Nimotuzumab has the potential to be a promising therapy agent, which may be useful in the treatment of patients with EGF-R positive cancer.

  10. Potential therapeutic radiotracers: preparation, biodistribution and metabolic characteristics of 177Lu-labeled cyclic RGDfK dimer.

    Science.gov (United States)

    Shi, Jiyun; Liu, Zhaofei; Jia, Bing; Yu, Zilin; Zhao, Huiyun; Wang, Fan

    2010-06-01

    In this study, we reported the preparation and evaluation of (177)Lu-DOTA-RGD2, (177)Lu-DOTA-Bz-RGD2 and (177)Lu-DTPA-Bz-RGD2 (RGD2 = E[c(RGDfK)](2)) as a potential therapeutic radiotracers for the treatment of integrin alpha(v)beta(3)-positive tumors. The BALB/c nude mice bearing the U87MG human glioma xenografts were used to evaluate the biodistribution characteristics and excretion kinetics of (177)Lu-DOTA-RGD2, (177)Lu-DOTA-Bz-RGD2 and (177)Lu-DTPA-Bz-RGD2. It was found that there were no major differences in their lipophilicity and biodistribution characteristics, particularly at latter time points. A major advantage of using DTPA-Bz as the bifunctional chelator (BFC) was its high radiolabeling efficiency (fast and high yield radiolabeling) at room temperature. Using DOTA and DOTA-Bz as BFCs, the radiolabeling kinetics was slow, and heating at 100 degrees C and higher DOTA-conjugate concentration were needed for successful (177)Lu-labeling. Therefore, DTPA-Bz is an optimal BFC for routine preparation of (177)Lu-labeled cyclic RGDfK peptides, and (177)Lu-DTPA-Bz-RGD2 is worthy of further investigation for targeted radiotherapy of integrin alpha(v)beta(3)-positive tumors.

  11. Scintillating screens for micro-imaging based on the Ce-Tb doped LuAP single crystal films

    OpenAIRE

    Douissard, Paul-Antoine; MARTIN, Thierry; Riva, Federica; Mathieu, Eric; Zorenko, Yuriy; Savchyn, Volodymyr; Zorenko, Tetyana; Fedorov, Alexander

    2014-01-01

    Single Crystal Film (SCF) scintillators are key-components of today's high-resolution 2D X-ray detectors used at synchrotrons for applications such as X-ray Radiography, Computed Tomography (CT), laminography, full-field XANES, and topography. Due to its high density and effective atomic number, LuAlO3 (LuAP) perovskite has a great potential to replace or complement the currently used Eu-doped Gd3Ga5O12 (GGG:Eu) and Tb-doped Lu2SiO5 (LSO:Tb) SCFs. In this article we present the growth of LuAP...

  12. Preparation of LuAG Powders with Single Phase and Good Dispersion for Transparent Ceramics Using Co-Precipitation Method

    Directory of Open Access Journals (Sweden)

    Liangjie Pan

    2015-08-01

    Full Text Available The synthesis of pure and well dispersed lutetium aluminum garnet (LuAG powder is crucial and important for the preparation of LuAG transparent ceramics. In this paper, high purity and well dispersed LuAG powders have been synthesized via co-precipitation method with lutetium nitrate and aluminum nitrate as raw materials. Ammonium hydrogen carbonate (AHC was used as the precipitant. The influence of aging time, pH value, and dripping speed on the prepared LuAG powders were investigated. It showed that long aging duration (>15 h with high terminal pH value (>7.80 resulted in segregation of rhombus Lu precipitate and Al precipitate. By decreasing the initial pH value or accelerating the dripping speed, rhombus Lu precipitate was eliminated and pure LuAG nano powders were synthesized. High quality LuAG transparent ceramics with transmission >75% at 1064 nm were fabricated using these well dispersed nano LuAG powders.

  13. Effective lattice stabilization of gadolinium aluminate garnet (GdAG via Lu3+ doping and development of highly efficient (Gd,LuAG:Eu3+ red phosphors

    Directory of Open Access Journals (Sweden)

    Jinkai Li, Ji-Guang Li, Zhongjie Zhang, Xiaoli Wu, Shaohong Liu, Xiaodong Li, Xudong Sun and Yoshio Sakka

    2012-01-01

    Full Text Available The metastable garnet lattice of Gd3Al5O12 is stabilized by doping with smaller Lu3+, which then allows an effective incorporation of larger Eu3+ activators. The [(Gd1−xLux1−yEuy]3Al5O12 (x = 0.1–0.5, y = 0.01–0.09 garnet solid solutions, calcined from their precursors synthesized via carbonate coprecipitation, exhibit strong luminescence at 591 nm (the 5D0 → 7F1 magnetic dipole transition of Eu3+ upon UV excitation into the charge transfer band (CTB at ~239 nm, with CIE chromaticity coordinates of x = 0.620 and y = 0.380 (orange-red. The quenching concentration of Eu3+ was estimated at ~5 at.% (y = 0.05, and the quenching was attributed to exchange interactions. Partial replacement of Gd3+ with Lu3+ up to 50 at.% (x = 0.5 while keeping Eu3+ at the optimal content of 5 at.% does not significantly alter the peak positions of the CTB and 5D0 → 7F1 emission bands but slightly weakens both bands owing to the higher electronegativity of Lu3+. The effects of processing temperature (1000–1500 °C and Lu/Eu contents on the intensity, quantum efficiency, lifetime and asymmetry factor of luminescence were thoroughly investigated. The [(Gd0.7Lu0.30.95Eu0.05]3Al5O12 phosphor processed at 1500 °C exhibits a high internal quantum efficiency of ~83.2% under 239 nm excitation, which, in combination with the high theoretical density, favors its use as a new type of photoluminescent and scintillation material.

  14. Langston University - High Energy Physics (LU-HEP)

    Energy Technology Data Exchange (ETDEWEB)

    Snow, Dr., Joel [Langston Univ., OK (United States)

    2012-08-13

    This final report is presented by Langston University (LU) for the project entitled "Langston University High Energy Physics" (LUHEP) under the direction of principal investigator (PI) and project director Professor Joel Snow. The project encompassed high energy physics research performed at hadron colliders. The PI is a collaborator on the DZero experiment at Fermi National Accelerator Laboratory in Batavia, IL, USA and the ATLAS experiment at CERN in Geneva, Switzerland and was during the entire project period from April 1, 1999 until May 14, 2012. Both experiments seek to understand the fundamental constituents of the physical universe and the forces that govern their interactions. In 1999 as member of the Online Systems group for Run 2 the PI developed a cross-platform Python-based, Graphical User Interface (GUI) application for monitoring and control of EPICS based devices for control room use. This served as a model for other developers to enhance and build on for further monitoring and control tasks written in Python. Subsequently the PI created and developed a cross-platform C++ GUI utilizing a networked client-server paradigm and based on ROOT, the object oriented analysis framework from CERN. The GUI served as a user interface to the Examine tasks running in the D\\O\\ control room which monitored the status and integrity of data taking for Run 2. The PI developed the histogram server/control interface to the GUI client for the EXAMINE processes. The histogram server was built from the ROOT framework and was integrated into the D\\O\\ framework used for online monitoring programs and offline analysis. The PI developed the first implementation of displaying histograms dynamically generated by ROOT in a Web Browser. The PI's work resulted in several talks and papers at international conferences and workshops. The PI established computing software infrastructure at LU and U. Oklahoma (OU) to do analysis of DZero production data and produce simulation

  15. Emergence and present status of Lu-177 in targeted radiotherapy. The Indian scenario

    Energy Technology Data Exchange (ETDEWEB)

    Banerjee, S.; Das, T.; Chakraborty, S.; Venkatesh, M. [Bhabha Atomic Reseach Centre, Trombay, Mumbai (India). Radiopharmaceuticals Div.

    2012-07-01

    {sup 177}Lu is presently considered to be a potential radionuclide for the development of agents for radionuclide therapy owing to its favorable nuclear decay characteristics [T{sub 1/2} = 6.65 d, E{sub {beta}}{sub (max)} = 0.497 MeV, E{sub {gamma}} = 113 KeV (6.4%) and 208 KeV (11%)]. While the long half-life of this promising radioisotope offers distinct logistic advantage, particularly, in countries having limited reactor facilities, the feasibility of its large-scale production with adequate specific activity and excellent radionuclidic purity in medium flux research reactors constitute yet another desirable feature. Extensive studies have been carried out to optimize the production of this isotope, with high specific activity and radionuclidic purity by the (n,{gamma}) route using the highest available flux and the optimum irradiation time. The gradual evolution of clin ical grade {sup 177}LuCl{sub 3} as a new radiochemical, ready for commercial deployment by Radiopharmaceuticals Division, Bhabha Atomic Research Centre, to nuclear medicine centers all over India was accomplished in 2010 in a stepwise manner with the commencement of the production of high specific activity {sup 177}Lu from enriched target in 2001. Research on {sup 177}Lu has demonstrated its immense potential in radiotherapeutic applications, a direct outcome of which has resulted in indigenous development of two agents viz. {sup 177}Lu-EDTMP and {sup 177}Lu-DOTA-TATE presently being evaluated in human patients for palliative care of bone pain due to skeletal metastases and treatment of malignancies of neuroendocrine origin, respectively. Using locally produced {sup 177}Lu, the radiolabeling of a plethora of other molecules with potential applicability in radiation synovectomy and targeted therapy of malignant tumors have been successfully demonstrated. A few of these agent such as a novel {sup 177}Lu-labeled porphyrin has shown considerable promise in initial studies and is presently evaluated

  16. High-temperature EBPR process: the performance, analysis of PAOs and GAOs and the fine-scale population study of Candidatus "Accumulibacter phosphatis".

    Science.gov (United States)

    Ong, Ying Hui; Chua, Adeline Seak May; Fukushima, Toshikazu; Ngoh, Gek Cheng; Shoji, Tadashi; Michinaka, Atsuko

    2014-11-01

    The applicability of the enhanced biological phosphorus removal (EBPR) process for the removal of phosphorus in warm climates is uncertain due to frequent reports of EBPR deterioration at temperature higher than 25 °C. Nevertheless, a recent report on a stable and efficient EBPR process at 28 °C has inspired the present study to examine the performance of EBPR at 24 °C-32 °C, as well as the PAOs and GAOs involved, in greater detail. Two sequencing batch reactors (SBRs) were operated for EBPR in parallel at different temperatures, i.e., SBR-1 at 28 °C and SBR-2 first at 24 °C and subsequently at 32 °C. Both SBRs exhibited high phosphorus removal efficiencies at all three temperatures and produced effluents with phosphorus concentrations less than 1.0 mg/L during the steady state of reactor operation. Real-time quantitative polymerase chain reaction (qPCR) revealed Accumulibacter-PAOs comprised 64% of the total bacterial population at 24 °C, 43% at 28 °C and 19% at 32 °C. Based on fluorescent in situ hybridisation (FISH), the abundance of Competibacter-GAOs at both 24 °C and 28 °C was rather low (temperature could have contributed to the presence of a unique clade. The clade IIF was hypothesised to be able to perform the EBPR activity at high temperatures. The clade's robustness most likely helps it to fit the high-temperature EBPR sludge best and allows it not only to outcompete other Accumulibacter clades but coexist with GAOs without compromising EBPR activity.

  17. Selective sludge removal in a segregated aerobic granular biomass system as a strategy to control PAO-GAO competition at high temperatures.

    Science.gov (United States)

    Winkler, M-K H; Bassin, J P; Kleerebezem, R; de Bruin, L M M; van den Brand, T P H; van Loosdrecht, M C M

    2011-05-01

    An aerobic granular sludge (AGS) reactor was run for 280 days to study the competition between Phosphate and Glycogen Accumulating Organisms (PAOs and GAOs) at high temperatures. Numerous researches have proven that in suspended sludge systems PAOs are outcompeted by GAOs at higher temperatures. In the following study a reactor was operated at 30 °C in which the P-removal efficiency declined from 79% to 32% after 69 days of operation when biomass removal for sludge retention time (SRT) control was established by effluent withdrawal. In a second attempt at 24 °C, efficiency of P-removal remained on average at 71 ± 5% for 76 days. Samples taken from different depths of the sludge bed analysed using Fluorescent in situ hybridization (FISH) microscopy techniques revealed a distinctive microbial community structure: bottom granules contained considerably more Accumulibacter (PAOs) compared to top granules that were dominated by Competibacter (GAOs). In a third phase the SRT was controlled by discharging biomass exclusively from the top of the sludge bed. The application of this method increased the P-removal efficiency up to 100% for 88 days at 30 °C. Granules selected near the bottom of the sludge bed increased in volume, density and overall ash content; resulting in significantly higher settling velocities. With the removal of exclusively bottom biomass in phase four, P-removal efficiency decreased to 36% within 3 weeks. This study shows that biomass segregation in aerobic granular sludge systems offers an extra possibility to influence microbial competition in order to obtain a desired population. Copyright © 2011 Elsevier Ltd. All rights reserved.

  18. Synthesis of Er-doped Lu2O3 nanoparticles and transparent ceramics

    Science.gov (United States)

    Serivalsatit, K.; Wasanapiarnpong, T.; Kucera, C.; Ballato, J.

    2013-05-01

    Transparent rare earth-doped Lu2O3 ceramics have received much attention for use in solid-state scintillator and laser applications. The fabrication of these ceramics, however, requires ultrafine and uniform powders as precursors. Presented here is the synthesis of Er-doped Lu2O3 nanopowders by a solution precipitation method using Er-doped lutetium sulfate solution and hexamethylenetetramine as a precipitant and the fabrication of Er-doped Lu2O3 transparent ceramics from these nanopowders. The precipitated precursors were calcined at 1100 °C for 4 h in order to convert the precursors into Lu2O3 nanoparticles with an average particle size of 60 nm. Thermal decomposition and phase evolution of the precursors were studied by simultaneous thermal analysis (STA), Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). Er-doped Lu2O3 transparent ceramics were fabricated from these nanopowders using vacuum sintering followed by hot isostatic pressing at 1700 °C for 8 h. The transparent ceramics exhibit an optical transmittance of 78% at a wavelength of 1.55 μm.

  19. Progress in the development of LuAlO3 based scintillators

    CERN Document Server

    Belsky, A; Lecoq, P; Dujardin, C; Garnier, N; Canibano, H; Pédrini, C; Petrosian, A

    2000-01-01

    LuAlO3:Ce3+ (LuAP) and LuxY1-xAlO3:Ce3+ (LuYAP) crystals are the promote scintillation materials for Positron Emission Tomography. Actual study of these scintillators develops in the tree directions: (i) growth of large size LuAP crystals with stable properties, (ii) relationship between composition of LuYAP crystals and scintillation properties, and (iii) scintillation mechanisms in lutetium compounds. After improving of growth conditions a large size samples (length greater than 40 mm) have been prepared. Crystals show a good correlation between growth parameters, light yield and transmission spectra. We performed a series of samples with calibrated size (2x2x10 mm3) and compare the light yield with a standard BGO and LSO samples. Mixed crystals with composition of 0.6 less than x less than 0.8 show a significant increase of light yield. We suggest that the short order clusterisation in mixed crystals may by playing an important role in governing the scintillation efficiency. In order to clarify the scintil...

  20. Pressure induced phase transition and thermo-physical properties in LuX (X = N, P)

    Science.gov (United States)

    Sahoo, B. D.; Mukherjee, D.; Joshi, K. D.; Kaushik, T. C.; Gupta, Satish C.

    2016-04-01

    Detailed total energy calculations have been performed in lutetium pnictides (LuX, where X = N, P) to understand their high pressure structural stability. In LuN, the ambient rocksalt type structure (B1 phase) transforms to a tetragonal structure (B10 phase) at ˜240 GPa; whereas in LuP the orthorhombic structure (B33, space group Cmcm) emerges as a high pressure structure above 48 GPa. Both the transitions are found to be of first-order type with volume discontinuities of ˜6% and 8.2%, respectively. The high pressure phases B10 and B33 are found to be stable up to 400 GPa, respectively. Further, the structural stability predicted from static lattice calculations has been supported by lattice dynamical stability analysis. The present calculations rule out the B1 to B2 (CsCl type) structural phase transitions predicted to occur at 241 GPa in LuN and at 98 GPa in LuP by previous all-electron calculations (Gupta and Bhat 2013 J. Mol. Model 19 5343-54). The temperature dependence of several thermo-physical properties such as volume, bulk modulus, specific heat and thermal expansion coefficient of the rocksalt structure of these compounds calculated in the present study, using quasi-harmonic approximation, awaits confirmation by experimental studies.

  1. Investigation of luminescence from LuAG: Mn4+ for physiological temperature sensing

    Science.gov (United States)

    Li, Fei; Cai, Jiajia; Chi, FengFeng; Chen, Yonghu; Duan, Changkui; Yin, Min

    2017-04-01

    Optical thermometry based on luminescent materials has garnered much attention due to its many advantages. But higher sensitivity is still expected in physiological temperature range which is of special significance in medicine and biology. For this purpose, quadrivalent manganese doped lutetium aluminum garnet, Lu3Al5O12: Mn4+, or simply LuAG: Mn4+, has been successfully synthesized by sol-gel method and its temperature dependent luminescence has been investigated in the present work. Compared to the common red emission phosphors Y3Al5O12: Mn4+ (YAG:Mn4+) with same structure, LuAG:Mn4+ has a stronger crystal field strength and a higher thermal-quenching activation energy (ΔE) of 5732 cm-1. Rapid thermal quenching of the Mn4+ luminescence occurred above room temperature around 90 °C for our LuAG:Mn4+ sample. Temperature dependent decay curves of Mn4+ emission from LuAG:Mn4+ revealed that an extraordinary high sensitivity can be achieved from luminescence lifetime measurements covering physiological temperature range with a sensitivity of 3.75% K-1 at 38 °C.

  2. Synthesis and luminescent properties of Pr-doped Lu3Al5O12 translucent ceramic

    Institute of Scientific and Technical Information of China (English)

    ZHAO Jiangbo; WANG Zhifang; WANG Chaonan; WEI Xiantao; LI Yong; ZHANG Weiping; YIN Min

    2009-01-01

    Lutetium aluminum garnet (LuAG) precursors doped with different Pr3+ concentration (0.25at.%, 0.5at.%, 1.0at.%, 3.0at.%, 5.0at.%) were synthesized via a co-precipitation method using ammonium hydrogen carbonate as precipitant. The phase evolution and mor-phology of the precursor were characterized with X-ray diffractometer (XRD) and transmission electron microscopy (TEM). The resultant LuAG:Pr3+ powder was sintered into translucent ceramic without any additives in vacuum at 1150℃ and then in nitrogen atmosphere at 1700℃. Photohiminescence spectra of LuAG:Pr3+ powder and ceramic were measured at room temperature in vacuum ultraviolet (VUV) and ultraviolet (VU) region. For the 5d-4f transition of Pr3+ ions, dominant emission of ceramic samples peaking round 311 nm had higher lumines-cence intensity. And the host absorption in ceramic samples was not as intensive as that in powder samples. The luminescent intensity of LuAG:Pr3+ varied with the Pr3+ contents and the quenching concentration was about 1.0at.% for ceramic and 3.0at.% for powder, which was much higher than 0.24at.% for LuAG:Pr3+ single crystals. This phenomenon showed that the ceramic had some superiority over single crystals.

  3. {sup 177}Lu-DOTA-lanreotide: a novel tracer as a targeted agent for tumor therapy

    Energy Technology Data Exchange (ETDEWEB)

    Banerjee, Sharmila; Das, Tapas; Chakraborty, Sudipta; Samuel, Grace; Korde, Aruna; Srivastava, Sudha; Venkatesh, Meera E-mail: meerav@apsara.barc.ernet.in; Pillai, M.R.A

    2004-08-01

    {sup 177}Lu of specific activity {approx}100-110 TBq/g and radionuclidic purity of {approx}100% was obtained by irradiation of enriched Lu{sub 2}O{sub 3} (60.6% {sup 176}Lu) target for 7 days at a thermal neutron flux of 3x10{sup 13}n/cm{sup 2}/sec. The {sup 177}Lu labeling of a macrocyclic bifunctional chelating agent viz. 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) has been extensively studied. Lanreotide, [{beta}-naphthyl-Ala-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH{sub 2}] a disulfide-linked cyclic octapeptide and a somatostatin analog, reported to bind with a wide variety of tumors expressing somatostatin receptors, was conjugated with DOTA. The peptide-BFCA conjugate was characterized with the help of high-resolution two-dimensional proton NMR spectroscopy. The {sup 177}Lu labeling of the DOTA-lanreotide conjugate has been standardized to give a radiolabeling yield of 85%. The tracer showed specific binding with A-431 human epidermoid carcinoma and IMR-32 human brain neuroblastoma cells.

  4. Absence of justice : Lu Chengming's struggle for compensation

    Energy Technology Data Exchange (ETDEWEB)

    Bai, L.

    2008-03-10

    This article described the efforts of Chinese citizen Lu Chengming to claim compensation from the Chinese government after being forcibly re-located during the building of the Three Gorges hydroelectric project. Research conducted by the author revealed that many households were not compensated for being resettled, and that many people who had lived in the region became refugees. Lu Chengming's family became unemployed after his hotel was demolished in 2002. The family of 11 was then divided into 4 in order to further reduce the amount of subsidies owed to them. Appeals to higher authorities began in 1993. Since then, Lu Chengming has only received the most basic welfare assistance. This article provided a translation of Lu Chengming's testimony as well as his account of the resettlement procedures. It was concluded that while the Chinese government consistently refuses his claims, Lu Chengming continues to live in hope that the government will award him his settlement. 4 refs., 3 figs.

  5. Complex cytokine modulation of a continuous line of mink lung epithelial cells (Mv1Lu).

    Science.gov (United States)

    Kelley, J; Baldor, L; Absher, M

    1992-01-01

    The continuous mink lung epithelial cell line Mv1Lu has proven to be a sensitive reporter line in the bioassay for purified TGF-beta, exhibiting a sigmoid-shaped concentration-response relationship with an EC50 of 12 pM (0.3 ng/mL). Maximal inhibition of Mv1Lu cells generates a 75-95% decrement in the number of adherent cells. However, this bioassay is not specific for TGF-beta as originally claimed. Mv1Lu cells are sensitive to other cytokines and substances found in complex biological fluids. In this study the effects of other biological response modifiers in this assay were tested and several were found to have important growth modulatory capacities that confound the quantitation of TGF-beta. EGF, TGF-alpha, fibronectin, and IGF-I all induce Mv1Lu cell proliferation. In contrast, neither PDGF (-AA, -AB, -BB) nor endotoxin ( or = 10 ng/mL) are the only cytokines examined that inhibit Mv1Lu proliferation. TGF-beta decreases final cell number both by preventing mitosis and by inhibition of adherence of cells to the uncoated dish. Several strategies are suggested to assure the specificity of this otherwise convenient bioassay for TGF-beta.

  6. Production of {sup 177}Lu, a potential radionuclide for diagnostic and therapeutic applications

    Energy Technology Data Exchange (ETDEWEB)

    Khandaker, Mayeen Uddin; Kassim, Hasan Abu [Department of Physics, University of Malaya, 50603 Kuala Lumpur (Malaysia); Haba, Hiromitsu [Nishina Center for Accelerator-Based Science, RIKEN, Wako, Saitama 351-0198 (Japan)

    2015-04-24

    {sup 177g}Lu (T{sub 1/2}=6.647d; E{sub β{sup −max}}=498.3KeV, I{sub β{sup −total}}=100%; E{sub γ} = 112.9498 keV, I{sub γ} = 6.17%; E{sub γ} = 208.3662 keV, I {sub γ} = 10.36%) is widely used in many clinical procedures due to its excellent decay characteristics. Production cross-sections of the {sup nat}Yb(d,x){sup 177g}Lu reactions have been measured from a 24-MeV deuteron energy down to the threshold by using a stacked-foil activation technique combined with high resolution γ-ray spectrometry. An overall good agreement is found with some of the earlier measurements, whereas a partial agreement is obtained with the theoretical data extracted from the TENDL-2013 library. Physical thick target yield for the {sup 177g}Lu radionuclide was deduced using the measured cross-sections. The deduced yield curves indicate that a low energy (<11 MeV) cyclotron and a highly enriched {sup 176}Yb target could be used to obtain {sup 177g}Lu with negligible impurity from {sup 177m}Lu.

  7. Thermal expansion properties of Lu2-x FexMo3O12

    Institute of Scientific and Technical Information of China (English)

    Wu Mei-Mei; Peng Jie; Zu Yong; Liu Rong-Deng; Hu Zhong-Bo; Liu Yun-Tao; Chen Dong-Feng

    2012-01-01

    The structures and thermal expansion properties of Lu2-xFex Mo3O12 have been investigated by X-ray diffraction (XRD).XRD patterns at room temperature indicate that componnds Lu2 xFexMo3O12 with x ≤ 1.3 exhibit an orthorhombic structure with space group Pnca;compounds with x =1.5 and 1.7 have a monoclinic structure with space group P21/a.Studies on thermal expansion properties show that the linear thermal expansion coefficients of orthorhombic phase vary from negative to positive with increasing Fe content.Attempts to make zero thermal expansion materials indicate that zero thermal expansion can be observed in Lu1.3Feo.7Mo3O12 in the temperature range of 200-400°C.

  8. Composite phosphor films based on spherical Lu2O3:Eu3+ nanoparticles

    Science.gov (United States)

    Babaevskaya, N. V.; Kryzhanovskaya, A. S.; Matveevskaya, N. A.; Mateichenko, P. V.; Yavetskii, R. P.; Tolmachev, A. V.; Tret'yak, S. E.

    2011-02-01

    A nanopowder of Lu2O3:Eu3+ ( C Eu = 5 at.%) was obtained by coprecipitation with urea (NH2)2CO from aqueous solutions. Using this nanopowder, compact Lu2O3:Eu3+ films with thicknesses within 20-200 μm and a relative density up to 65% of the theoretical limit were deposited using the spin-coating and painting techniques. The films were characterized by scanning electron microscopy, X-ray diffraction, and X-ray luminescence (XRL) measurements. It is established that the XRL intensity depends on the phosphor/organic binder ratio and thickness of the film. The most intense XRL and most homogeneous structure are observed for 20-μm-thick Lu2O3:Eu3+ films.

  9. Magnetic and magnetotransport properties of the orthorhombic perovskites (Lu,Ca)MnO3

    Science.gov (United States)

    Imamura, N.; Karppinen, M.; Motohashi, T.; Yamauchi, H.

    2008-01-01

    Here we extend the research of the (R,Ca)MnO3 perovskites to the smallest- R end member (Lu,Ca)MnO3 . Magnetic and magnetotransport properties of the (Lu1-xCax)MnO3 system are systematically investigated in regard to carrier doping. It is found that hole doping into the antiferromagnetic x=0.0 phase, LuMnO3 , causes a spin-glass-like magnetic competition in the wide doping range of 0.1≤x≤0.6 , whereas electron doping into the antiferromagnetic x=1.0 phase, CaMnO3 , induces a large magnetoresistance effect for 0.8≤x≤0.95 .

  10. Large magneto (thermo) dielectric effect in multiferroic orthorhombic LuMnO3

    Science.gov (United States)

    Wang, L. J.; Chai, Y. S.; Feng, S. M.; Zhu, J. L.; Manivannan, N.; Jin, C. Q.; Gong, Z. Z.; Wang, X. H.; Li, L. T.

    2012-06-01

    We have investigated the relation between ferroelectric and magnetic orders of orthorhombic (o-) LuMnO3 ceramics. The increase of dielectric constant ɛ exceeds 82% near incommensurate to commensurate E-type antiferromagnetic (AFM) spin ordering transition temperature TL, reflecting a large magneto (thermo) dielectric response. Meanwhile, distinct anomalies and thermal hysteresis behavior are observed near this temperature in both temperature dependence of ɛ and specific heat Cp, indicating a strong coupling between FE and magnetic orders in o-LuMnO3. Comparing to o-HoMnO3, TmMnO3, and YbMnO3 with similar E-type AFM ground state, o-LuMnO3 has the largest magneto (thermo) dielectric effect

  11. Toxicity of trastuzumab labeled {sup 177}Lu on MCF7 and SKBr3 cell lines

    Energy Technology Data Exchange (ETDEWEB)

    Rasaneh, Samira [Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box 14115-331, Tehran (Iran, Islamic Republic of); Rajabi, Hossein, E-mail: hrajabi@modares.ac.i [Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box 14115-331, Tehran (Iran, Islamic Republic of); Hossein Babaei, Mohammad; Johari Daha, Fariba [Department of Radioisotope, Nuclear Science and Technology Research Institute, Tehran (Iran, Islamic Republic of)

    2010-10-15

    In this study, we labeled trastuzumab with {sup 177}Lu to synthesize a new radiopharmaceutical for therapy of breast cancer and at the first stage investigated its therapeutic effects on SKBr3 and MCF7 breast cancer cell lines. Trastuzumab-{sup 177}Lu showed very good in-vitro characteristics such as high radiochemical purity (91{+-}0.9%), good stability in PBS buffer (86{+-}2.3%) and blood serum (81{+-}2.7%) up to 96 h, appropriate immunoreactivity (85.4{+-}1.1%) and high cytotoxicity in HER2 expression cells. 5 fold increase in toxicity of trastuzumab-{sup 177}Lu was observed when compared with unlabeled trastuzumab on SKBr3 cells.

  12. Scintillation properties of a La, Lu-admix gadolinium pyrosilicate crystal

    Energy Technology Data Exchange (ETDEWEB)

    Kurosawa, Shunsuke, E-mail: kurosawa@imr.tohoku.ac.jp [Institute for Materials Research (IMR), Tohoku University 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); New Industry Creation Hatchery Center (NICHe) 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); Shishido, Toetsu; Suzuki, Akira; Sugawara, Takamasa; Nomura, Akiko; Yubuta, Kunio [Institute for Materials Research (IMR), Tohoku University 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Shoji, Yasuhiro [Institute for Materials Research (IMR), Tohoku University 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); C& A Corporation, 6-6-40 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Yokota, Yuui [New Industry Creation Hatchery Center (NICHe) 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); Pejchal, Jan [New Industry Creation Hatchery Center (NICHe) 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); Institute of Physics, AS CR, Cukrovarnická 10, 162 53 Prague (Czech Republic); Ohashi, Yuji [Institute for Materials Research (IMR), Tohoku University 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Kamada, Kei [New Industry Creation Hatchery Center (NICHe) 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); C& A Corporation, 6-6-40 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Yoshikawa, Akira [Institute for Materials Research (IMR), Tohoku University 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); New Industry Creation Hatchery Center (NICHe) 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); C& A Corporation, 6-6-40 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8577 (Japan)

    2015-06-01

    In order to obtain new scintillator with higher effective atomic number, a pyrosilicate crystal with a composition (Ce{sub 0.01}, Gd{sub 0.54}, La{sub 0.25}, Lu{sub 0.20}){sub 2}Si{sub 2}O{sub 7} (Ce:LaLu-GPS) was grown by the floating zone method. Emission wavelengths of this material were at 370 and 390 nm. Gamma-ray-excited pulse height and scintillation decay measurement showed that Ce:LaLu-GPS had a light output of 34,000±2000 photons/MeV, an FWHM energy resolution of 6.9±0.2%, and the decay time components of 59±1 ns (13%) and 570±20 ns (87%)

  13. Standardization and measurement of gamma-ray probability per decay of 177Lu.

    Science.gov (United States)

    Dias, Mauro S; Silva, Fabrício F V; Koskinas, Marina F

    2010-01-01

    The procedure followed by the Nuclear Metrology Laboratory (LMN), at the Nuclear and Energy Research Institute (IPEN), for the primary standardization of (177)Lu is described. This radionuclide is widely used in radiopharmacy due to its convenient half-life and emitted beta ray energies. The (177)Lu solution was supplied during an international comparison sponsored by BIPM in 2009 and the primary standardization has been accomplished by the 4pibeta-gamma coincidence method using a proportional counter in 4pi geometry coupled with two NaI(Tl) scintillation counters. The beta efficiency was varied by placing Collodion and aluminum absorbers over and under the radioactive source. The (177)Lu calibrated sources were also measured in a previously calibrated HPGe spectrometer, in order to obtain the emission probability per decay for the selected gamma-ray transitions. The experimental extrapolation curves were also compared with Monte Carlo simulations by means of code ESQUEMA developed at the LMN.

  14. Electronic and magnetic properties of LuFe{sub 2}O{sub 4}

    Energy Technology Data Exchange (ETDEWEB)

    Kuepper, Karsten [Institut fuer Festkoerperphysik, Universitaet Ulm (Germany); Raekers, Michael; Taubitz, Christian; Prinz, Manuel; Derks, Christine; Neumann, Manfred [Fachbereich Physik, Universitaet Osnabrueck (Germany); Postnikov, Andrei V. [LPMD, Paul Verlaine University and Institute Jean Barriol, Metz (France); Groot, Frank M.F. de [Department of Inorganic Chemistry and Catalysis, Utrecht University (Netherlands); Piamonteze, Cinthia [Swiss Light Source, Paul Scherrer Institut, Villigen (Switzerland); Prabhakaran, Dharmalingam; Blundell, Stephen J. [Department of Physics, University of Oxford, Clarendon Laboratory, Oxford (United Kingdom)

    2010-07-01

    LuFe{sub 2}O{sub 4} is a compound showing fascinating magneto electric coupling via charge ordering. Electronic and magnetic properties of the charge ordered phase of LuFe{sub 2}O{sub 4} are investigated by means of X-ray spectroscopic and theoretical electronic structure approaches. We identified the electronic states of the valence band by means of valence band XPS-, and XES-spectroscopies, and GGA+U first principles calculations. Moreover, by applying XMCD, we are able to identify the spin ground state of LuFe{sub 2}O{sub 4} in the charge ordered phase to be a 2:1 ferrimagnetic configuration, ruling out a frustrated magnetic state.

  15. Predictor-Corrector LU-SGS Discontinuous Galerkin Finite Element Method for Conservation Laws

    Directory of Open Access Journals (Sweden)

    Xinrong Ma

    2015-01-01

    Full Text Available Efficient implicit predictor-corrector LU-SGS discontinuous Galerkin (DG approach for compressible Euler equations on unstructured grids is investigated by adding the error compensation of high-order term. The original LU-SGS and GMRES schemes for DG method are discussed. Van Albada limiter is employed to make the scheme monotone. The numerical experiments performed for the transonic inviscid flows around NACA0012 airfoil, RAE2822 airfoil, and ONERA M6 wing indicate that the present algorithm has the advantages of low storage requirements and high convergence acceleration. The computational efficiency is close to that of GMRES scheme, nearly 2.1 times greater than that of LU-SGS scheme on unstructured grids for 2D cases, and almost 5.5 times greater than that of RK4 on unstructured grids for 3D cases.

  16. A Zeybek folk dance in Blacksea region: Sepetçioğlu

    Directory of Open Access Journals (Sweden)

    Gülşah Yüksel

    2010-12-01

    Full Text Available Normal 0 21 false false false TR X-NONE X-NONE MicrosoftInternetExplorer4 Productions of folk literature consist of emotions, desires, needs, social textures, life dynamisms as well as all accepted behaviours and toughts of a society. Folk dances which is a one dimension of folk literature conveys clues of events that happened in the history up to current times. Story of Sepetcioğlu represents a folk hero who stands for protecting its people. As a version of “zeybek” folk dances, Sepetcioğlu takes an important place in Turkish culture with its swift figures, its story and with its folk song. This study aims document characteristics of Sepetçioğlu folk dance, including its song and its story.

  17. Trakya University Güllapoğlu Arboretum Landscape Planning Studies

    Directory of Open Access Journals (Sweden)

    A. B. Korkut

    2008-09-01

    Full Text Available The aim of this study is to determine the planning rules of the arboretum to be established in Trakya University Güllapoğlu Campus and propose landscape plan. In thıs study, several researches are made on Trakya University Güllapoğlu Arboretum in Trakya University Campus in Edirne. First of all the concept of “Arboretum”, functions, planning and application criteria and the properties of arboretums in Turkey and other countries are studied. The socio-economical structure of Edirne where Güllapoğlu arboretum will be established is studied and the establishg reasons of arboretum in Edirne were determined. Afterwords the natural properties [slop, soil, flora] of the arboretum are collected and the results are analysed.

  18. 玉红膏治疗手部皲裂性湿疹疗效观察%Clinical Effects of YuHongGao in Treating Hand Eczema Fissum

    Institute of Scientific and Technical Information of China (English)

    呼荟茹; 贾育蓉; 贾育新

    2012-01-01

    目的:观察玉红膏治疗手部皲裂性湿疹的临床疗效.方法:玉红膏外用治疗手部皲裂性湿疹56例,观察症状及体征改善情况.结果:治愈率42.0%,总有效率100%.结论:玉红膏外用治疗手部皲裂性湿疹疗效确切.%Objective: To observe clinical effects of YuHongGao in treating hand eczema fissum. Method: 56 cases of hand eczema fissum were given by YuHongGao. The improvements of symptom and sign were explored. Result: The cure rate was 42.0%, total effective rate was 100%. Conclusion: YuHongGao in treating hand eczema fissum can obtain definite effects.

  19. Characterization of Pr:LuAG scintillating crystals for X-ray spectroscopy

    Science.gov (United States)

    Bertoni, R.; Bonesini, M.; Cervi, T.; Clemenza, M.; De Bari, A.; Falcone, A.; Mazza, R.; Menegolli, A.; Nastasi, M.; Rossella, M.

    2016-07-01

    The main features of the Pr doped Lu3Al5O12 (Pr:LuAG) scintillating crystals for X-ray spectroscopy applications have been studied using different radioactive sources and photo-detectors. Pr:LuAG is cheaper, compared to a Germanium detector, but with remarkable properties which make it useful for many applications, from fundamental physics measurements to the PET imaging for medical purposes: high density, elevate light yield, fast response, high energy resolution, no hygroscopicity. A sample of Pr:LuAG crystals with 14 mm×14 mm surface area and 13 mm thickness and a NaI crystal of the same surface and 26 mm thickness used as a reference have been characterized with several radioactive sources, emitting photons in the range 100-1000keV. Different light detectors were adopted for the Pr:LuAG studies, sensitive to its UV emission (peak at 310 nm): a 3 in. PMT (Hamamatsu R11065) and new arrays of Hamamatsu SiPM S13361, with siliconic resin as a window. Preliminary results are presented on the performance of the Pr:LuAG crystals, to be mounted in a 2 × 2 array to be tested in the 2015 run of the FAMU experiment at RIKEN-RAL muon facility. The goal is the detection of the X-rays (around 130 keV) emitted during the de-excitation processes of the muonic hydrogen after the excitation with an IR laser with wavelength set at the resonance of the hyperfine splitting, to measure the muonic atom proton radius with unprecedented precision.

  20. [177Lu]Bz-DTPA-EGF: Preclinical characterization of a potential radionuclide targeting agent against glioma.

    Science.gov (United States)

    Sundberg, Asa Liljegren; Gedda, Lars; Orlova, Anna; Bruskin, Alexander; Blomquist, Erik; Carlsson, Jörgen; Tolmachev, Vladimir

    2004-04-01

    Patients with glioblastoma multiforme have a poor prognosis due to recurrences originating from spread cells. The use of radionuclide targeting might increase the chance of inactivating single tumor cells with minimal damage to surrounding healthy tissue. As a target, overexpressed epidermal growth factor receptors (EGFR) may be used. A natural ligand to EGFR, the epidermal growth factor (EGF) is an attractive targeting agent due to its low molecular weight (6 kDa) and high affinity for EGFR. 177Lu (T(1/2) = 6.7 days) is a radionuclide well suited for treatment of small tumor cell clusters, since it emits relatively low-energy beta particles. The goal of this study was to prepare and preclinically evaluate both in vitro and in vivo the [177Lu]Bz-DTPA-EGF conjugate. The conjugate was characterized in vitro for its cell-binding properties, and in vivo for its pharmacokinetics and ability to target EGFR. [177Lu]Bz-DTPA-EGF bound to cultured U343 glioblastoma cells with an affinity of 1.9 nM. Interaction with EGFR led to rapid internalization, and more than 70% of the cell-associated radioactivity was internalized after 30 minutes of incubation. The retention of radioactivity was good, with more than 65% of the 177Lu still cell-associated after 2 days. Biodistribution studies of i.v. injected [177Lu]Bz-DTPA-EGF in NMRI mice demonstrated a rapid blood clearance. Most of the radioactivity was found in the liver and kidneys. The liver uptake was receptor-mediated, since it could be significantly reduced by preinjection of unlabeled EGF. In conclusion, [177Lu]Bz-DTPA-EGF seems to be a promising candidate for locoregional treatment of glioblastoma due to its high binding affinity, low molecular weight, and ability to target EGFR in vivo.

  1. Evaluation of two intraoperative gamma detectors for assessment of (177)Lu activity concentration in vivo.

    Science.gov (United States)

    Sandblom, Viktor; Ståhl, Ingun; Olofsson Bagge, Roger; Forssell-Aronsson, Eva

    2017-12-01

    Patients with somatostatin receptor-expressing neuroendocrine tumours can be treated with intravenously administered (177)Lu-octreotate. Few patients are cured with the present protocol due to the current dose limitation of normal organs at risk, such as the kidneys. By locally administering (177)Lu-octreotate to the liver for the purpose of treating liver metastases, a substantially reduced absorbed dose to organs at risk could be achieved. The development of such a technique requires the capability of measuring the (177)Lu activity concentration in tissues in vivo. The aim of this study was to evaluate different performance parameters of two commercially available intraoperative gamma detectors in order to investigate whether intraoperative gamma detector measurements could be used to determine (177)Lu activity concentration in vivo. Measurements were made using different sources containing (177)Lu. Response linearity, sensitivity, spatial resolution and its depth dependence, organ thickness dependence of the measured count rate and tumour detectability were assessed for two intraoperative gamma detectors. The two detectors (a scintillation and a semiconductor detector) showed differences in technical performance. For example, the sensitivity was higher for the scintillation detector, while the spatial resolution was better for the semiconductor detector. Regarding organ thickness dependence and tumour detectability, similar results were obtained for both detectors, and even relatively small simulated tumours of low tumour-to-background activity concentration ratios could be detected. Acceptable results were obtained for both detectors, although the semiconductor detector proved more advantageous for our purpose. The measurements demonstrated factors that must be corrected for, such as organ thickness or dead-time effects. Altogether, intraoperative gamma detector measurements could be used to determine (177)Lu activity concentration in vivo.

  2. A Comparison of Lu You’s Phoenix Hairpin and Elizabeth Barrett Browning’s Sonnets from the Portuguese (43)

    Institute of Scientific and Technical Information of China (English)

    雷华

    2010-01-01

    Both Lu You and Elizabeth Barrett Browning enjoy great popularity as a poet.In this paper I compare and contract Lu You’s well-known love ci-poem Phoenix Hairpin with Elizabeth Barrett Browning’s famous Sonnets from the Portuguese (43) in respect of theme,style,and way of expression.

  3. Optical and scintillation properties of Ce3+ doped LiYF4 and LiLuF4 crystals

    NARCIS (Netherlands)

    Combes, CM; Dorenbos, P; vanEijk, CWE; Pedrini, C; DenHartog, HW; Gesland, JY; Rodnyi, PA

    1997-01-01

    Optical properties of LiYF4:Ce and LiLuF4:Ce were studied viz. optical absorption spectra and X-ray induced emission spectra. The scintillation characteristics of LiYF4:Ce and LiLuF4:Ce were investigated viz. gamma-ray induced pulse height spectra and decay time measurements. A model is presented to

  4. Os modelos de realeza em São Luís, segundo Joinville

    OpenAIRE

    2011-01-01

    O objetivo deste trabalho é identificar os modelos de realeza em Luís IX, rei da França entre 1226 e 1270, tendo como base principalmente a obra de Jean de Joinville intitulada Histoire de Saint Louis. No decorrer da análise, constata-se o caráter peculiar do documento como espelho de príncipe, gênero medieval que procura estabelecer um modelo ideal de realeza. Luís IX é nele retratado como um rei peregrino, cruzado que ampliou o reino de Deus na terra, buscando identificá-lo ao reino de Cris...

  5. Magnetic excitations in multiferroic LuMnO3 studied by inelastic neutron scattering

    Science.gov (United States)

    Lewtas, H. J.; Boothroyd, A. T.; Rotter, M.; Prabhakaran, D.; Müller, H.; Le, M. D.; Roessli, B.; Gavilano, J.; Bourges, P.

    2010-11-01

    We present data on the magnetic and magnetoelastic coupling in the hexagonal multiferroic manganite LuMnO3 from inelastic neutron scattering, magnetization, and thermal-expansion measurements. We measured the magnon dispersion along the main symmetry directions and used this data to determine the principal exchange parameters from a spin-wave model. An analysis of the magnetic anisotropy in terms of the crystal field acting on the Mn is presented. We compare the results for LuMnO3 with data on other hexagonal RMnO3 compounds.

  6. Esthesioneuroblastoma (olfactory neuroblastoma) treated with 111In-octreotide and 177Lu-DOTATATE PRRT.

    Science.gov (United States)

    Makis, William; McCann, Karey; McEwan, Alexander J B

    2015-04-01

    A 51-year-old man with a recurrent metastatic esthesioneuroblastoma (olfactory neuroblastoma) was referred for peptide receptor radionuclide therapy (PRRT). He received 4 treatments of 111In-octreotide over 8 months and 3 treatments of 177Lu-DOTATATE over 4 months, which helped alleviate his symptoms and improved his quality of life; however, the tumor ultimately progressed and he passed away shortly thereafter. PRRT with 111In-octreotide or 177Lu-DOTATATE could play a role in the management of esthesioneuroblastoma.

  7. Proton Decay Studies of the Light Lu, Tm and Ho Isotopes

    Energy Technology Data Exchange (ETDEWEB)

    Akovali, Y.; Batchelder, J.C.; Bingham, C.R.; Davinson, T.; Ginter, T.N.; Gross, C.J.; Grzywacz, R.; Hamilton, J.H.; Janas, Z.; Karny, M.; Kim, S.H.; MacDonald, B.D.; Mas, J.F.; McConnell, J.W.; Piechaczek, A.; Ressler, J.J.; Rykaczewski, K.; Slinger, R.C.; Szerypo, J.; Toth, K.S.; Weintraub, W.; Woods, P.J.; Yu, C.-H.; Zganjar, E.F.

    1998-10-15

    A double-sided Si-strip detector system has been installed and commissioned at the focal plane of the Recoil Mass Spectrometer at the Holifield Radioactive Ion Beam Facility. The system can be used for heavy charged particle emission studies with half-lives as low as a few {micro}sec. In this paper the authors present identification and study of the decay properties of the five new proton emitters: {sup 140}Ho, {sup 141m}Ho, {sup 145}Tm, {sup 150m}Lu and {sup 151m}Lu.

  8. Optimization of LSO/LuYAP phoswich detector for small animal PET

    Science.gov (United States)

    Jung, Jin Ho; Choi, Yong; Chung, Yong Hyun; Devroede, Olivier; Krieguer, Magalie; Bruyndonckx, Peter; Tavernier, Stefaan

    2007-02-01

    LSO/LuYAP phoswich detectors for small animal PET were developed to measure the depth of interaction (DOI), and to improve the spatial resolution at the edge of the field of view (FOV). The aim of this study was to optimize the optical coupling conditions between the crystal and photomultiplier tube (PMT) to maximize the light-collection efficiency, and to develop a method for rejecting scatter events by applying an equal energy window in each crystal layer. The light yields of the phoswich detector were estimated by changing the refractive index of the optical coupling material using a DETECT simulation. The accuracy of the DOI measurement on the phoswich detector, using an optical coupling material with the optimal light yield, were evaluated experimentally and compared with the air condition. The energy window for the photopeak events cannot be applied properly because the light outputs of LSO and LuYAP are different. The LSO/LuYAP photopeaks need to be superposed in order to effectively discriminate the scattered events by applying an equal energy window. The photopeaks of the LSO and LuYAP can be superposed by inserting a reflecting material between the crystals. The optimal coverage ratio of the inserting material was derived from a DETECT simulation, and its performance was investigated. In the simulation result, optimal refractive index of the optical coupling material was 1.7. The average DOI measurement errors of the LSO/LuYAP were 0.6%/3.4% and 4.9%/41.4% in the phoswich detector with and without an optical coupling material, respectively. The photopeaks of the LSO and LuYAP were superposed by covering 75% of the contact surface between the crystals with white Teflon. The DOI measurement errors of the LSO/LuYAP were 0.2%/2.4%. In this study, the optimal condition of the optical coupling material inserted between the crystal and PMT was derived to improve the accuracy of DOI measurement, and a photopeak superposition method of the LSO and LuYAP was

  9. Production of non carrier added (n.c.a.) {sup 177}Lu for radiopharmaceutical applications

    Energy Technology Data Exchange (ETDEWEB)

    Barkhausen, Christoph

    2011-09-06

    The goal of this dissertation was the development of a process to produce non carrier added {sup 177}Lu at the FRM II. For this purpose, preparative chromatographic methods were evaluated and applied. The highest quality of the nuclide which could only be achieved through a complex chemical process, has been already been proven by clinical studies to be very advantageous. The process has been built up in a hot cell as a semi-automated process and is now being adapted to the requirements of the 'Arzneimittelgesetz' in order to establish n.c.a. {sup 177}Lu as a pharmaceutical product.

  10. Anisotropic Multiband Many-Body Interactions in LuNi2B2C

    Energy Technology Data Exchange (ETDEWEB)

    Bergk, B.; Petzold, V.; Rosner, H.; Drechsler, S.-L.; Bartkowiak, M.; Ignatchik, O.; Bianchi, A. D.; Sheikin, I.; Canfield, P. C.; Wosnitza, J.

    2008-06-27

    We present a comprehensive de Haas-van Alphen study on the nonmagnetic borocarbide superconductor LuNi{sub 2}B{sub 2}C. The analysis of the angular-dependent effective masses for different bands in combination with full-potential density functional calculations allowed us to determine the mass-enhancement factors, {lambda}, for the different electronic bands and their wave-vector dependences. Our data clearly show the anisotropic multiband character of the superconductivity in LuNi{sub 2}B{sub 2}C.

  11. The regulation of prostitution in Beyoğlu (1875-1915).

    Science.gov (United States)

    özbek, Müge

    2010-01-01

    This study examines the development and nature of the regulation of prostitution in Beyoğlu during the late Ottoman Empire with special emphasis on the way the regulationist regime reinforced existing patterns of class and gender domination. The regulation of prostitution became a matter of urgency in the last decades of the nineteenth century in Istanbul, particularly in Beyoğlu, the cosmopolitan centre of the city. Through this process, the protests of the local residents of the area objecting to the proliferation of prostitution in their neighbourhoods played a crucial role in prompting the governmental authorities to tighten the regulations.

  12. Analysis of GAO Shi′s Idea on Social Concern and Assisting Society%浅析高适的“济世”理想

    Institute of Scientific and Technical Information of China (English)

    高立强

    2014-01-01

    GAO Shi was a great poet at glorious age of the Tang Dynasty ,he loved his country and had a strong disire to serve his country,though there were many setbacks before him,he had never stopped trying for ideal. The poet concentrated on lives of ordinary people,he dared to reveal the dark side of the society,Gao shi had special insights about border area policy of the Tang Dynasty,there were positive meanings in his peoms.%高适是盛唐杰出的诗人,他心怀天下,有着积极的济世理想,尽管遭遇诸多挫折,但诗人穷其一生都在为入仕而做积极的努力。诗人能够关注下层普通民众的生活,勇于揭露社会的阴暗面,对于唐王朝的边疆政策,有着独到的见解,这些都是有积极意义的。

  13. 高力士受唐玄宗器重原因探析%The Reasons of Gao Lishi being Valued by Tang Xuanzong

    Institute of Scientific and Technical Information of China (English)

    王瑜

    2013-01-01

    In the early Tang dynasty ,members of royal family often launched palace coups together with the outer court ministers .The fre-quent palace coups led to instable politics and the distrust of emperors to the outer court ministers .Then the inner court eunuchs power rose . One of best known was Gao Lishi who was deeply valued by Tang Xuanzong .Gao was featured with his political and military talents of loyal-ty ,cautious and holistic implementation ,monarch-subject communication ,advice-making as well as riding and shooting .%唐朝前期,皇室成员常常和外朝大臣联合发动宫廷政变,频繁的宫廷政变导致政局不稳,也引起了皇帝对外朝大臣的不信任,比较而言更为信任的是内朝宦官,宦官势力由此崛起,而其中的翘楚则当属高力士。高力士深受唐玄宗的器重的原因,除了生逢其时,还因他有对玄宗忠贞不渝、办事谨密、善于沟通君臣关系、适时对玄宗提出规谏、擅长骑射等政治和军事才能。

  14. 黄公望的“高远”式构图法赏析%Appreciation of GaoYuan type composition method of Huang Gongwang

    Institute of Scientific and Technical Information of China (English)

    谢凌凌

    2014-01-01

    Beijing's Palace Museum Danya Yushu Figure was used as the research object in this paper. The Huang Gongwang 's GaoYuan type composition method, which adopt antitheses and look down at the landscape to obtain"scene of outside mountains", was studied base on analysis of three viewing angles:looking up, looking squarely and look down at the landscape, and the drawing method of mountains, rocks and trees. On Guoxi,s landscape painting method basis, it is result that Huang Gongwang 's way is to innovate the GaoYuan type composition method.%以北京故宫博物院藏《丹崖玉树图》为研究对象,基于仰视、平视、俯视三个观察角度以及山峦巨石及树木的浅绛画法分析,研究黄公望采用对比法、鸟瞰视角获取“山外之景”的“高远”式的构图方法。在郭熙的山水画法基础上,黄公望的构图方法是对“高远”式构图法进行了创新。

  15. Tl response of KMgF{sub 3}: Lu + PTFE at ultraviolet radiation; Respuesta Tl de KMgF{sub 3}: Lu + PTFE a radiacion ultravioleta

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, P.R. [Instituto Nacional de Investigaciones Nucleares, A.P. 18 -1027, 11801 Mexico D.F. (Mexico); Alarcon, N.G. [Facultad de Quimica, Universidad Autonoma del Estado de Mexico. Paseo Tollocan, Esq. con Jesus Carranza, 50180 Toluca, Estado de Mexico (Mexico); Furetta, C.; Azorin, J. [Universidad Autonoma Metropolitana- Iztapalapa, San Rafael Atlixco 186, 09340 Mexico. D.F. (Mexico)

    2003-07-01

    Ionizing radiation has different types of interaction with a crystalline solid. However, only few effects are interesting to optimize some thermoluminescent (Tl) properties of certain Tl materials. This paper presents results obtained by irradiating KMgF{sub 3}: Lu + Ptfe Tl dosimeters with ultraviolet (UV) radiation previously exposed to gamma radiation. These results showed that those dosimeters not exposed previously to gamma radiation did not presented any Tl signal. Meanwhile, those previously submitted to gamma irradiation showed that their sensitivity was increased as the gamma dose increased. The glow curve of sensitized KMgF{sub 3}: Lu + Ptfe exposed to UV radiation, presented the dosimetric pea at 212 C. This makes this material to be promissory for measuring UV radiation. (Author)

  16. Luminescence Properties of Tb3+-Doped LuAG Films Prepared by Pechini Sol-Gel Method

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Lu3Al5O12 (LuAG) thin films with different Tb3+ concentration were prepared on carefully cleaned (111) silicon wafer by a Pechini process and dip-coating technique. Heat treatment was performed in the temperature range from 800 to 1100 ℃. The crystal structure was analyzed by XRD. The results show that LuAG film starts to crystallize at about 900 ℃, and the particle size increases with the sintering temperature. Excitation and emission spectra of Tb3+ doped LuAG films were measured. The effects of heat-treatment temperature and doping concentration of Tb3+ on the luminescent properties were also investigated. For a comparison study, Tb3+-doped LuAG powders were also prepared by the same sol-gel method.

  17. Comparison of the luminescent properties of LuAG:Pr nanopowders, crystals and films using synchrotron radiation

    Science.gov (United States)

    Gorbenko, V.; Zych, E.; Voznyak, T.; Nizankovskiy, S.; Zorenko, T.; Zorenko, Yu.

    2017-04-01

    Comparison of the luminescent properties of nanopowder, single crystal and single crystalline film of Pr3+ doped Pr-doped Lu3Al5O12 garnet (LuAG:Pr) prepared by the different technological methods is performed in this work using the time-resolved emission spectroscopy under excitation by synchrotron radiation with an energy of 3.7-25 eV at 300 K and 10 K. The notable differences in the properties of the Pr3+ luminescence are observed in LuAG:Pr crystals and films caused by involving the LuAl antisite defects and oxygen vacancies in crystals and Pb2+ flux related dopant in films in the excitation processes of the Pr3+ luminescence. At the same time, we have also found that the influence of host defects on the Pr3+ luminescence is significantly smaller in the LuAG:Pr nanopowders.

  18. Influenza Pandemic: Continued Focus on the Nation's Planning and Preparedness Efforts Remains Essential. Testimony before the Ad Hoc Subcommittee on State, Local, and Private Sector Preparedness and Integration, Senate Committee on Homeland Security and Governmental Affairs. GAO-09-760T

    Science.gov (United States)

    Steinhardt, Bernice

    2009-01-01

    As the recent outbreak of the H1N1 (swine flu) virus underscores, an influenza pandemic remains a real threat to our nation and to the world. Over the past 3 years, the US Government Accountability Office (GAO) has conducted a body of work to help the nation better prepare for a possible pandemic. In a February 2009 report, GAO synthesized the…

  19. Meteorite zircon constraints on the bulk Lu-Hf isotope composition and early differentiation of the Earth.

    Science.gov (United States)

    Iizuka, Tsuyoshi; Yamaguchi, Takao; Hibiya, Yuki; Amelin, Yuri

    2015-04-28

    Knowledge of planetary differentiation is crucial for understanding the chemical and thermal evolution of terrestrial planets. The (176)Lu-(176)Hf radioactive decay system has been widely used to constrain the timescales and mechanisms of silicate differentiation on Earth, but the data interpretation requires accurate estimation of Hf isotope evolution of the bulk Earth. Because both Lu and Hf are refractory lithophile elements, the isotope evolution can be potentially extrapolated from the present-day (176)Hf/(177)Hf and (176)Lu/(177)Hf in undifferentiated chondrite meteorites. However, these ratios in chondrites are highly variable due to the metamorphic redistribution of Lu and Hf, making it difficult to ascertain the correct reference values for the bulk Earth. In addition, it has been proposed that chondrites contain excess (176)Hf due to the accelerated decay of (176)Lu resulting from photoexcitation to a short-lived isomer. If so, the paradigm of a chondritic Earth would be invalid for the Lu-Hf system. Herein we report the first, to our knowledge, high-precision Lu-Hf isotope analysis of meteorite crystalline zircon, a mineral that is resistant to metamorphism and has low Lu/Hf. We use the meteorite zircon data to define the Solar System initial (176)Hf/(177)Hf (0.279781 ± 0.000018) and further to identify pristine chondrites that contain no excess (176)Hf and accurately represent the Lu-Hf system of the bulk Earth ((176)Hf/(177)Hf = 0.282793 ± 0.000011; (176)Lu/(177)Hf = 0.0338 ± 0.0001). Our results provide firm evidence that the most primitive Hf in terrestrial zircon reflects the development of a chemically enriched silicate reservoir on Earth as far back as 4.5 billion years ago.

  20. ¹⁷⁷Lu-Labeled Agents for Neuroendocrine Tumor Therapy and Bone Pain Palliation in Uruguay.

    Science.gov (United States)

    Balter, Henia; Victoria, Trindade; Mariella, Terán; Javier, Gaudiano; Rodolfo, Ferrando; Andrea, Paolino; Graciela, Rodriguez; Juan, Hermida; Eugenia, De Marco; Patricia, Oliver

    2016-01-01

    Lutetium-177 is an emerging radionuclide due its convenient chemical and nuclear properties. In this paper we describe the development and evaluation in Uruguay of the targeted 177Lu labelled radiopharmaceuticals EDTMP (for bone pain palliation) and DOTA-TATE (neuroendocrine tumors). We optimized the preparation of these 177Lu radiopharmaceuticals including radiolabelling, quality control methods, in vitro and in vivo stability and their therapeutic application in patients. Radiation dosimetry aspects of 177Lu are also included. Nine male patients with prostate cancer and four female patients with breast carcinoma with multiple bone metastatic lesions were treated with 177Lu-EDTMP. Four patients with gastroentheropancreatic neuroendocrine tumors (GEP-NET) and one patient with bronchial NET were treated with 1- 3 cycles with a cumulative dose of 4.44-22.2 GBq of 177Lu-DOTA-TATE. Scintigraphic images of the patients treated with 177Lu-EDTMP evidenced high and rapid uptake in bone metastasis, remaining after 7 days post administration. Images allow skeletal visualization with high definition and demonstrate increased uptake in bone metastases. For 177Lu-DOTA-TATE, partial remissions were obtained in 4 patients and the remaining patient did not show significant progression 3 months after the second cycle. No serious adverse effects were registered, even in two patients with confirmed renal disease and high risk for renal disease Dosimetry assessments confirm the predictive value of the personalized therapy with radiolabelled peptides. We found it is possible to accumulate high therapeutic doses in tumours in sequential administrations of 177Lu-DOTA-TATE, increasing the probability of biological response without significant impairment of the renal function in patients with risk factors. These results demonstrate the attractive therapeutic properties of these two 177Lu labelled agents and the feasibility of this metabolic therapy in regions far away from 177Lu producing

  1. Low threshold monocrystalline Nd:(Gd,Lu)2O3 channel waveguide laser

    NARCIS (Netherlands)

    Kahn, Andreas; Heinrich, Sebastian; Kühn, Henning; Petermann, Klaus; Bradley, J.; Worhoff, Kerstin; Pollnau, Markus; Huber, Günther

    2009-01-01

    We report the first waveguide laser based on a rare-earth-doped sesquioxide. A 2 μm thick lattice matched Nd(0.5%):${(Gd, Lu)_2O_3}$ film with a nearly atomically flat surface has been epitaxially grown on a $Y_2O_3$ substrate, using pulsed laser deposition. The film has been structured with reactiv

  2. THE USE OF SEMI INHERITED LU FACTORIZATION OF MATRICES IN INTERPOLATION OF DATA

    Directory of Open Access Journals (Sweden)

    MOHAMMAD ALI FARIBORZI ARAGHI

    2009-04-01

    Full Text Available The polynomial interpolation in one dimensional space R is an important method to approximate the functions. The Lagrange and Newton methods are two well known types of interpolations. In this work, we describe the semi inherited interpolation for approximating the values of a function. In this case, the interpolation matrix has the semi inherited LU factorization.

  3. Enhanced local lattice distortions with the antiferromagnetic transition in the multiferroic LuMnO3

    Science.gov (United States)

    Louca, Despina; Proffen, Thomas; Lee, Seung-Hun; Cheong, Sang-Wook

    2009-03-01

    The ferroelectric hexagonal manganite, LuMnO3, has been investigated via neutron scattering and the pair density function analysis to determine the nature of the local atomic distortions with the antiferromagnetic transition, TN, of the Mn ions. While in previously reported neutron diffraction data, it was shown that all atomic coordinates changed based on symmetry considerations with TN, we hereby show that it is the ferroelectric motion of the Lu ions coupled with O distortions that exhibits a strong temperature dependence below TN as reflected in the Lu-O bonds. This suggests an enhancement of the net electric polarization below TN. At the same time, the motion of the apical O1 and O2 ions distorts the MnO5 bipyramids, leading to more buckling of the ab-layers. However, the Mn ions do not appear to distort significantly away from their equilibrium position. The oxygen distortions induced with the spin reorientations below TN may be the cause for the Lu ion displacements through electrostatic interactions and this in turn produces coupling to the electric dipole moments.

  4. Hüsteeria, seks ja selektiivne mälu / Anneli Porri

    Index Scriptorium Estoniae

    Porri, Anneli, 1980-

    2006-01-01

    Marge Monko näitus "Uurimusi kodanlusest" (Charcot' klassifitseeritud krambiasendeid esitab tantsija Krõõt Juurak) Hobusepea galeriis 17.-22. V; Jane Suviste ja Piibe Piirma näitus "Editeeritud mälu" Tallinna Linnagaleriis kuni 28. V; Andres Lõo kureeritud noortenäitus "Sex" Vaal-galeriis 2.-20. V

  5. Transport properties of Ho1- x Lu x B12 solid solutions

    Science.gov (United States)

    Gabáni, S.; Bat'ko, I.; Bat'ková, M.; Flachbart, K.; Gaz̆o, E.; Pristás̆, G.; Takác̆ová, I.; Bogach, A. V.; Sluchanko, N. E.; Shitsevalova, N. Yu.

    2013-05-01

    Our studies of Ho1- x Lu x B12 solid solutions have shown that the temperature of antiferromagnetic (AF) order in geometrically frustrated system of HoB12 ( T N = 7.4 K) is linearly suppressed to zero temperature, i.e. T N → 0, as lutetium concentration increases to x→ x c ≈ 0.9. In this contribution, we present original results of electrical resistivity measurements on Ho1- x Lu x B12 single crystalline samples with x = 0, 0.2, 0.5, 0.7, 0.9, 1 in the temperature range 0.06-300 K and in magnetic fields ( B) up to 8 T. Complex B vs T N phase diagrams were received from precise temperature ρ( T) and field ρ( B) dependences of resistivity with several AF phases for x ≤ 0.5 pointing to a possibility of quantum critical point at x c ≈ 0.9. The scattering of conduction electrons in the AF phase and in the paramagnetic phase as well as Hall effect results are analyzed and discussed for various concentrations x, when magnetic dilution increases with the increasing content of nonmagnetic Lu ions in the Ho1- x Lu x B12 system.

  6. Hüsteeria, seks ja selektiivne mälu / Anneli Porri

    Index Scriptorium Estoniae

    Porri, Anneli, 1980-

    2006-01-01

    Marge Monko näitus "Uurimusi kodanlusest" (Charcot' klassifitseeritud krambiasendeid esitab tantsija Krõõt Juurak) Hobusepea galeriis 17.-22. V; Jane Suviste ja Piibe Piirma näitus "Editeeritud mälu" Tallinna Linnagaleriis kuni 28. V; Andres Lõo kureeritud noortenäitus "Sex" Vaal-galeriis 2.-20. V

  7. lu olemuse jälile juhatas meritigu / Tiit Kändler

    Index Scriptorium Estoniae

    Kändler, Tiit, 1948-

    2000-01-01

    Columbia ülikooli teadlane, tänavuse Nobeli meditsiini- ja füsioloogiapreemia saanud Eric Kandel uuris aplüüsia toel välja, kuidas aju asju mäletab. Skeem : Mälu põhineb keemiliste muutuste säilitamisel

  8. Attēlu apstrādes rīks datorredzes algoritmiem

    OpenAIRE

    Briņģe, Līna

    2016-01-01

    Kvalifikācijas darba produkts "Attēlu apstrādes rīks datorredzes algoritmiem" ir lietojumprogramma, kas paredzēta ātrai un vieglai attēlu apstrādei. Šīs programmas mērķis ir padarīt ērtāku un ātrāku attēlu kopu sagatavošanu, kas paredzētas dažādu datorredzes algoritmu izmantošanai un testēšanai. Programma piedāvā lietotājam izgriezt attēla reģionus, atlasīt vēlamos saglabāšanas kritērijus un eksportēt iegūtos datus kā jaunus attēlus. Tā rezultātā tiek iegūts ievadattēlu aprakstošs fails, kas ...

  9. 1047-nm all-solid-state laser based on Nd: LuLF

    Institute of Scientific and Technical Information of China (English)

    Rui Li; Ting Yu; Lianhan Zhang; Weibiao Chen; Yin Hang

    2011-01-01

    @@ A compact all-solid-state continuous-wave (CW) laser at 1047 nm is developed based on Nd:LuLF, which is grown through the Czochralski technique. From the laser system, 1.3-W laser can be obtained, which corresponds to the slope efficiencies of 20.1% and 49.5% with respect to the incident and absorbed pump powers, respectively. To the best of our knowledge, this is the highest power level achieved at 1047 nm based on the Nd:LuLF crystal.%A compact all-solid-state continuous-wave (CW) laser at 1047 nm is developed based on Nd:LuLF, which is grown through the Czochralski technique. From the laser system, 1.3-W laser can be obtained, which corresponds to the slope efficiencies of 20.1% and 49.5% with respect to the incident and absorbed pump powers, respectively. To the best of our knowledge, this is the highest power level achieved at 1047 nm based on the Nd:LuLF crystal.

  10. Three-phonon stimulated Raman scattering in an orthorhombic LuAlO3 crystal

    Science.gov (United States)

    Kaminskii, A. A.

    2016-12-01

    High-order stimulated Raman scattering (SRS) has been revealed in a LuAlO3 crystal upon stationary picosecond laser excitation. All recorded Stokes and anti-Stokes χ(3)-nonlinear laser components are attributed to three SRS-promoting A g vibrational modes of its octahedral anionic units (AlO3)-3.

  11. EXAFS investigation and luminescent properties of nanosized Tb: Lu2O3 phosphors

    Institute of Scientific and Technical Information of China (English)

    REN

    2010-01-01

    Nanosized terbium doped Lu2O3 phosphors were synthesized via a modified co-precipitation processing.The as-prepared Tb:Lu2O3 phosphors was consisted of well crystallized nanosized sphere particles with a diameter of about 30 nnx Local structure of Tb ions in Lu2O3 lattice was investigated by an analytical approach based on Fourier transformation of the extended X-ray absorption fine structure(EXAFS) data.X-ray near edge structure (XANES) spectra suggested that all Tb ions doped were tervalonce.EXAFS results indicated that Tb ions have entered the Lu2O3 cubic lattice by means of solid solution.The coordination number and first shell Tb-O distance dropped with the increasing of Tb concentration.Emission spectra of the phosphors was shown to be typical for Tb3+ with main components at 542,550 and 490 nm,derived from irradiative relaxation of 5D4 level.The emission intensity decreased severely with the increasing of Tb concentration from 1 mol.% to 15 tool.%,suggesting a significant concentration quenching above 1 mol.% Tb.The reduction of emission intensity was interpreted by higher distortion derived relaxation among the surface state resident Tb3+ ions.

  12. lu olemuse jälile juhatas meritigu / Tiit Kändler

    Index Scriptorium Estoniae

    Kändler, Tiit, 1948-

    2000-01-01

    Columbia ülikooli teadlane, tänavuse Nobeli meditsiini- ja füsioloogiapreemia saanud Eric Kandel uuris aplüüsia toel välja, kuidas aju asju mäletab. Skeem : Mälu põhineb keemiliste muutuste säilitamisel

  13. Pärnu Õlu omanikuks sai Soome ärimees / Andris Feldmanis

    Index Scriptorium Estoniae

    Feldmanis, Andris, 1982-

    2004-01-01

    Pärnu Õlletehase senine suuromanik Charlie Viikberg müüs oma osaluse Soome ärimehele Carl-Erik Sundbladile kuuluvale CES Holding AS-ile. Uue omaniku peaeesmärgiks kasvatada turuosa 10 protsendile. Diagramm: Pärnu Õlu väikeses kasumis

  14. An Improved Algorithm for Parallel Sparse LU Decomposition on a Distributed-Memory Multiprocessor

    NARCIS (Netherlands)

    Koster, J.; Bisseling, R.H.

    2001-01-01

    In this paper we present a new parallel algorithm for the LU decomposition of a general sparse matrix Among its features are matrix redistribution at regular intervals and a dynamic pivot search strategy that adapts itself to the number of pivots produced. Experimental results obtained on a network

  15. Demonstration of a hybrid Ho:YLF Ho:LuLF slab laser

    CSIR Research Space (South Africa)

    Esser, MJD

    2010-10-01

    Full Text Available The authors present a continuous-wave slab laser utilising both Ho:YLF and Ho:LuLF as laser gain media. 30 W of output power at 2 µm was demonstrated in a stable concave-plane resonator while 13 W was achieved in a hybrid stable...

  16. Bright Lu2 O3 :Eu Thin-Film Scintillators for High-Resolution Radioluminescence Microscopy.

    Science.gov (United States)

    Sengupta, Debanti; Miller, Stuart; Marton, Zsolt; Chin, Frederick; Nagarkar, Vivek; Pratx, Guillem

    2015-07-16

    The performance of a new thin-film Lu2 O3 :Eu scintillator for single-cell radionuclide imaging is investigated. Imaging the metabolic properties of heterogeneous cell populations in real time is an important challenge with clinical implications. An innovative technique called radioluminescence microscopy has been developed to quantitatively and sensitively measure radionuclide uptake in single cells. The most important component of this technique is the scintillator, which converts the energy released during radioactive decay into luminescent signals. The sensitivity and spatial resolution of the imaging system depend critically on the characteristics of the scintillator, that is, the material used and its geometrical configuration. Scintillators fabricated using conventional methods are relatively thick and therefore do not provide optimal spatial resolution. A thin-film Lu2 O3 :Eu scintillator is compared to a conventional 500 μm thick CdWO4 scintillator for radioluminescence imaging. Despite its thinness, the unique scintillation properties of the Lu2 O3 :Eu scintillator allow us to capture single-positron decays with fourfold higher sensitivity, which is a significant achievement. The thin-film Lu2 O3 :Eu scintillators also yield radioluminescence images where individual cells appear smaller and better resolved on average than with the CdWO4 scintillators. Coupled with the thin-film scintillator technology, radioluminescence microscopy can yield valuable and clinically relevant data on the metabolism of single cells. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Weak antilocalization effect and noncentrosymmetric superconductivity in a topologically nontrivial semimetal LuPdBi

    KAUST Repository

    Xu, Guizhou

    2014-07-21

    A large number of half-Heusler compounds have been recently proposed as three-dimensional (3D) topological insulators (TIs) with tunable physical properties. However, no transport measurements associated with the topological surface states have been observed in these half-Heusler candidates due to the dominating contribution from bulk electrical conductance. Here we show that, by reducing the mobility of bulk carriers, a two-dimensional (2D) weak antilocalization (WAL) effect, one of the hallmarks of topological surface states, was experimentally revealed from the tilted magnetic field dependence of magnetoconductance in a topologically nontrivial semimetal LuPdBi. Besides the observation of a 2D WAL effect, a superconducting transition was revealed at T c ∼ 1.7â.K in the same bulk LuPdBi. Quantitative analysis within the framework of a generalized BCS theory leads to the conclusion that the noncentrosymmetric superconductivity of LuPdBi is fully gapped with a possibly unconventional pairing character. The co-existence of superconductivity and the transport signature of topological surface states in the same bulk alloy suggests that LuPdBi represents a very promising candidate as a topological superconductor.

  18. Pretargeted 177Lu radioimmunotherapy of carcinoembryonic antigen-expressing human colonic tumors in mice.

    NARCIS (Netherlands)

    Schoffelen, R.; Graaf, W.T.A. van der; Franssen, G.M.; Sharkey, R.M.; Goldenberg, D.M.; McBride, W.J.; Rossi, E.A.; Eek, A.; Oyen, W.J.G.; Boerman, O.C.

    2010-01-01

    Pretargeted radioimmunotherapy (PRIT) with bispecific antibodies in combination with a radiolabeled peptide reduces the radiation dose to normal tissues, especially the bone marrow. In this study, the optimization, therapeutic efficacy, and toxicity of PRIT of colon cancer with a (177)Lu-labeled pep

  19. Unustagem kõvaketas, kasutagem operatiivmälu! / Katrin Ruus

    Index Scriptorium Estoniae

    Ruus, Katrin

    2008-01-01

    Valik Mart Viljuse, Katrin Teesi, Piret Räni, Reimo Võsa-Tangsoo, Merle ja Erki Kannuse ning rühmituste Puhas Rõõm ja Infotankistid viimaste aastate töödest näituseprojektina "Operatiivmälu" Pärnu Kunstnike Maja galeriis ja Pärnu Linnagaleriis. 11 ill

  20. Measurements of conversion electrons in the s-process branching point nucleus {sup 176}Lu

    Energy Technology Data Exchange (ETDEWEB)

    Battaglia, A.; Tan, W.; Avetisyan, R.; Casarella, C.; Gyurijinyan, A.; Manukyan, K.V.; Marley, S.T.; Nystrom, A.; Paul, N.; Siegl, K.; Smith, K.; Smith, M.K.; Strauss, S.Y.; Aprahamian, A. [University of Notre Dame, Department of Physics, Notre Dame, IN (United States)

    2016-05-15

    Conversion coefficients, gamma-gamma and gamma-electron coincidences were measured in the s-process branching point nucleus {sup 176}Lu. Our goal was to determine the multipolarities of the γ-ray transitions that connect the high and low K states of {sup 176}Lu. This {sup 176}Lu nucleus has a long-lived ground state (K=7{sup -}) of 37.6 Gy, a short-lived isomeric state (K=0{sup -}) at 122.8 keV with half-life of 3.6 h, as well as a 58 μs isomer at 1588 keV (K=14{sup +}). The excitation structure of this nucleus contains bands of intermediate spins of both positive and negative parities. The intermediate states can under certain stellar temperatures completely change the equilibrium between the isomer and ground state of {sup 176}Lu and change the abundance of this nucleus. We populated 37 previously known levels in this nucleus via the {sup 176}Yb(p,n) reaction and measured 42 conversion coefficients for γ-ray transitions including 17 of them for the first time. (orig.)

  1. Crystal fields at light rare-earth ions in Y and Lu

    DEFF Research Database (Denmark)

    Touborg, P.; Nevald, Rolf; Johansson, Torben

    1978-01-01

    Crystal-field parameters have been deduced for the light rare-earth solutes Ce, Pr, and Nd in Y or Lu hosts from measurements of the paramagnetic susceptibilities. In the analysis all multiplets in the lowest LS term were included. For a given host, crystal-field parameters divided by Stevens fac...

  2. Forward to cryogenic temperature: laser cooling of Yb: LuLiF crystal

    Science.gov (United States)

    Zhong, Biao; Luo, Hao; Lei, Yongqing; Shi, Yanling; Yin, Jianping

    2017-06-01

    The high quality Yb-doped fluoride crystals have broad prospects for optical refrigeration. We have laser cooled the Yb:LuLiF crystal to a temperature below the limit of current thermoelectric coolers ( 180 K). The 5% Yb:LuLiF crystal sample has a geometry of 2 mm×2 mm×5 mm and was supported by two fibers of 200 μm in diameter. They were placed in a 2×10-4 Pa vacuum chamber with an environment temperature of 294.5 K. The 1019 nm CW laser of power 38.7 W was adopted to irradiate the sample. The temperature of the sample was measured utilizing the DLT methods. After 20 minutes of laser irradiation, the 5% Yb:LuLiF crystal sample was cooled down to 182.4 K. By further optimizing experimental conditions and increasing the doped Yb concentration, the Yb:LuLiF crystal might be optically cooled below the cryogenic temperature of 123K in the near future.

  3. Vene uut kunsti ühendab mälu / Teet Veispak

    Index Scriptorium Estoniae

    Veispak, Teet, 1955-

    2007-01-01

    Näitusest "Mälu tagasitulek" Kumu Kunstimuuseumis, kuraator Viktor Misiano. Lähemalt David Ter-Oganjani (sünd. 1981) tööst "Vanad loosungid", Dmitri Prigovi (sünd. 1940) videost, Juri Leidermani installatsioonist "Isa jutustus", Jevgeni Fiksi tööst "Song of Russia"

  4. 2014年鲁迅研究述评%Review on the Research of Lu Xun in 2014

    Institute of Scientific and Technical Information of China (English)

    崔云伟; 刘增人

    2015-01-01

    In 2014, the study on Lu Xun's works took on a splendid and innovative situation.Wu Yiqin, Zhou Nan, Zhang Ke, etc.all presented brilliant ideas on Lu Xun's novels.Qian Liqun's research on Wild Grass,Yang Yi and Song Jianhua's study on Life is A Moment, Wei Jian's study on Lu Xun's essay, Tan Guilin's holistic study of Lu Xun's works were novel and distinctive.There are ten subjects which mainly focus on study of thought, for example, Lu Xun and Confucius, Lu Xun and Nietzsche, Lu Xun's individualistic consciousness, Lu Xun and Rusia, Lu Xun and the Soviet Union, Lu Xun's belief, Lu Xun and the Buddhism, Lu Xun and Chinese characters'reformation, Lu Xun and the Republic of China (1912—1949),Lu Xun and East Asia and so on.Feng Guanglian, Wang Weidong, Li Dongmu,etc.all presented marvelous works on Lu Xun's study.The following researches could refresh and enlighten us a lot to a certain degree, such as Lu Xun and academic study done by Zhao Jinghua, Lu Xun and art study done by Yang Yi, the study of Lu Xun's research made by Zhang Fugui and Tan Guilin.%2014年鲁迅研究呈现出异彩纷呈、创意不断的局面。吴义勤、周南、张克、张全之、杨义等皆对鲁迅小说发表了极为精彩的看法。钱理群的《野草》研究,杨义、宋剑华的《朝花夕拾》研究,魏建的鲁迅杂文研究,谭桂林的鲁迅作品整体研究,均有其新颖独到之处。思想研究主要集中为十个专题:鲁迅与孔子、鲁迅与尼采、鲁迅的个性意识、鲁迅与俄国、鲁迅与苏联、鲁迅的信仰、鲁迅与佛学、鲁迅与汉字改革、鲁迅与民国、鲁迅与东亚等,冯光廉、汪卫东、李冬木、朱德发、孙郁、李春林、谭桂林、张松、刘东方、文贵良、张中良、韩琛等的文章皆堪称优异之作。赵京华的鲁迅与学术研究,杨义的鲁迅与艺术研究,张福贵、谭桂林的鲁迅研究之研究,皆能予人以新的感受和认识。

  5. Photodynamic therapy trials with lutetium texaphyrin (Lu-Tex) in patients with locally recurrent breast cancer

    Science.gov (United States)

    Renschler, Markus F.; Yuen, Alan R.; Panella, Timothy J.; Wieman, Thomas J.; Dougherty, Shona; Esserman, Laura; Panjehpour, Masoud; Taber, Scott W.; Fingar, Victor H.; Lowe, Elizabeth; Engel, Julie S.; Lum, Bert; Woodburn, Kathryn W.; Cheong, Wai-Fung; Miller, Richard A.

    1998-05-01

    Photodynamic therapy (PDT) of locally recurrent breast cancer has been limited to treatment of small lesions because of non- selective necrosis of adjacent normal tissues in the treatment field. Lutetium Texaphyrin (PCI-0123, Lu-Tex) is a photosensitizer with improved tumor localization that is activated by 732 nm light, which can penetrate through larger tumors. We have evaluated Lu-Tex in a Phase I trial and in an ongoing Phase II trial in women with locally recurrent breast cancer with large tumors who have failed radiation therapy. Patients received Lu-Tex intravenously by rapid infusion 3 hours before illumination of cutaneous or subcutaneous lesions. In Phase I, Lu-Tex doses were escalated from 0.6 to 7.2 mg/kg in 7 cohorts. Sixteen patients with locally recurrent breast cancer lesions were treated. Dose limiting toxicities above 5.5 mg/kg were pain in the treatment field during therapy, and dysesthesias in light exposed areas. No necrosis of normal tissues in the treated field was noticed. Responses were observed in 60% of evaluable patients [n equals 15, 27% complete remission (CR), 33% partial remission (PR)], with 63% of lesions responding (n equals 73: 45% CR, 18% PR). In Phase II, 25 patients have been studied to date, receiving two treatments ranging from 1.0 to 3.0 mg/kg at a 21 day interval. Treatment fields up to 480 cm2 in size were treated successfully and activity has been observed. Patients have experienced pain at the treatment site but no tissue necrosis. These studies demonstrate the feasibility of Lu-Tex PDT to large chest wall areas in women who have failed radiation therapy for the treatment of locally recurrent breast cancer. Treatment conditions are currently being optimized in the ongoing Phase II trials.

  6. Autonomous parvovirus LuIII encapsidates equal amounts of plus and minus DNA strands

    Energy Technology Data Exchange (ETDEWEB)

    Bates, R.C.; Snyder, C.E.; Banerjee, P.T.; Mitra, S.

    1984-02-01

    Autonomous parvoviruses are thought to uniquely encapsidate single-stranded DNA of minus polarity. In contrast, the defective adeno-associated viruses separately encapsidate equal amounts of plus and minus DNA strands. The uniqueness of minus strand encapsidation is reexamined for the autonomous parvoviruses. Although it was found that Kilham rat virus and H-1 virus encapsidate varying but small amounts of complementary-strand DNA, it was unexpected to find that LuIII virus encapsidated equal amounts of plus and minus DNA. The extracted LuIII DNA possessed properties of double-stranded replicative-form DNA, including insensitivity to S1 endonuclease, cleavage by restriction enzymes, and conversion to unit-length, single-stranded DNA when electrophoresed under denaturing conditions. However, the inability of this DNA to form single-stranded DNA circles when denatured and then renatured in the presence of formamide and the lack of double-stranded DNA circle formation after treatment with exonuclease III and reannealing shows a lack of sequence homology of the 3' and 5' termini of LuIII DNA, in contrast to adeno-associated virus DNA. Digestion of LuIII double-stranded DNA with EcoRI and HincII and separation of plus and minus DNA strands on composite agarose-acrylamide gels identified a heterogeneity present only in the plus DNA strand. These results suggest that strand specificity of viral DNA encapsidation is not a useful property for differentiation between the autonomous and defective parvoviruses. Furthermore, encapsidation by LuIII of equal amounts of complementary DNA strands in contrast to encapsidation of minus strands by H-1 virus, when propagated in the same host cell type, suggests that selection of strands for encapsidation is a virus-coded rather than host-controlled event.

  7. Structural, microstructural and vibrational analyses of the monoclinic tungstate BiLuWO{sub 6}

    Energy Technology Data Exchange (ETDEWEB)

    Ait Ahsaine, H. [Laboratoire Matériaux et Environnement LME, Faculté des Sciences, Université Ibn Zohr, BP 8106 Cité Dakhla, Agadir (Morocco); Taoufyq, A. [Laboratoire Matériaux et Environnement LME, Faculté des Sciences, Université Ibn Zohr, BP 8106 Cité Dakhla, Agadir (Morocco); Institut Matériaux Microélectronique et Nanosciences de Provence, IM2NP, UMR CNRS 7334, Université de Toulon, BP 20132, 83957 La Garde Cedex (France); Patout, L. [Institut Matériaux Microélectronique et Nanosciences de Provence, IM2NP, UMR CNRS 7334, Université de Toulon, BP 20132, 83957 La Garde Cedex (France); Ezahri, M.; Benlhachemi, A.; Bakiz, B. [Laboratoire Matériaux et Environnement LME, Faculté des Sciences, Université Ibn Zohr, BP 8106 Cité Dakhla, Agadir (Morocco); Villain, S.; Guinneton, F. [Institut Matériaux Microélectronique et Nanosciences de Provence, IM2NP, UMR CNRS 7334, Université de Toulon, BP 20132, 83957 La Garde Cedex (France); Gavarri, J.-R., E-mail: gavarri.jr@univ-tln.fr [Institut Matériaux Microélectronique et Nanosciences de Provence, IM2NP, UMR CNRS 7334, Université de Toulon, BP 20132, 83957 La Garde Cedex (France)

    2014-10-15

    The bismuth lutetium tungstate phase BiLuWO{sub 6} has been prepared using a solid state route with stoichiometric mixtures of oxide precursors. The obtained polycrystalline phase has been characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Raman spectroscopy. In the first step, the crystal structure has been refined using Rietveld method: the crystal cell was resolved using monoclinic system (parameters a, b, c, β) with space group A2/m. SEM images showed the presence of large crystallites with a constant local nominal composition (BiLuW). TEM analyses showed that the actual local structure could be better represented by a superlattice (a, 2b, c, β) associated with space groups P2 or P2/m. The Raman spectroscopy showed the presence of vibrational bands similar to those observed in the compounds BiREWO{sub 6} with RE=Y, Gd, Nd. However, these vibrational bands were characterized by large full width at half maximum, probably resulting from the long range Bi/Lu disorder and local WO{sub 6} octahedron distortions in the structure. - Graphical abstract: The average structure of BiLuWO{sub 6} determined from X-ray diffraction data can be represented by A2/m space group. Experimental Electron Diffraction patterns along the [0vw] zone axes of the monoclinic structure and associated simulated patterns show the existence of a monoclinic superstructure with space group P2 or P2/m. - Highlights: • A new monoclinic BiLuWO{sub 6} phase has been elaborated from solid-state reaction. • The space group of the monoclinic disordered average structure should be A2/m. • Transmission electron microscopy leads to a superlattice with P2/m space group. • Raman spectroscopy suggests existence of local disorder.

  8. Environmental Health: Opportunities for Greater Focus, Direction, and Top-Level Commitment to Children's Health at EPA. Testimony Before the Committee on Environment and Public Works, U.S. Senate. GAO-10-545T

    Science.gov (United States)

    Stephenson, John B.

    2010-01-01

    This testimony discusses highlights of GAO's report about the Environmental Protection Agency's (EPA) efforts to institutionalize the protection of children's health. EPA's mission is to protect human health and the environment. As a result of mounting evidence about the special vulnerabilities of the developing fetus and child, the federal…

  9. State and Local Governments: Fiscal Pressures Could Have Implications for Future Delivery of Intergovernmental Programs. Report to the Ranking Member, Committee on the Budget, House of Representatives. GAO-10-899

    Science.gov (United States)

    Czerwinski, Stanley J.

    2010-01-01

    State and local governments work in partnership with the federal government to implement numerous intergovernmental programs. Fiscal pressures for state and local governments may exist when spending is expected to outpace revenues for the long term. GAO (Government Accountability Office) was asked to examine (1) the long-term fiscal pressures…

  10. Head Start: Undercover Testing Finds Fraud and Abuse at Selected Head Start Centers. Testimony before the Committee on Education and Labor, House of Representatives. GAO-10-733T

    Science.gov (United States)

    Kutz, Gregory D.

    2010-01-01

    The Head Start program, overseen by the Department of Health and Human Services and administered by the Office of Head Start, provides child development services primarily to low-income families and their children. Federal law allows up to 10 percent of enrolled families to have incomes above 130 percent of the poverty line--GAO (Government…

  11. [Gao Jingyi. Han yu yu bei Ou yu yan : Han yu yu Wula'er yu yan ji Yin Ou yu yan tong yuan tan jiu] / Ago Künnap

    Index Scriptorium Estoniae

    Künnap, Ago, 1941-

    2010-01-01

    Arvustus: Gao Jingyi. Han yu yu bei Ou yu yan : Han yu yu Wula'er yu yan ji Yin Ou yu yan tong yuan tan jiu = Chinese language and languages of northern Europe. Beijing : Zhongguo she hui ke xue chu ban she, 2008

  12. United States Merchant Marine Academy: Internal Control Weaknesses Resulted in Improper Sources and Uses of Funds; Some Corrective Actions Are Under Way. Report to Congressional Committees. GAO-09-635

    Science.gov (United States)

    Franzel, Jeanette M.

    2009-01-01

    The U.S. Merchant Marine Academy (Academy), a component of the Department of Transportation's Maritime Administration (MARAD), is one of five U.S. service academies. The Academy is affiliated with 14 nonappropriated fund instrumentalities (NAFI) and two foundations. The US Government Accountability Office (GAO) was asked to determine whether…

  13. Veteran Students Received Similar Amounts of Title IV Aid as Nonveterans but More Total Aid with GI Benefits. Report to the Ranking Member, Subcommittee on Economic Opportunity, Committee on Veterans' Affairs, House of Representatives. GAO-08-741

    Science.gov (United States)

    Scott, George A.

    2008-01-01

    In 2002, the Government Accountability Office (GAO) reported that veteran students were awarded similar amounts of Title IV aid as nonveteran students, and veterans' total federal aid was greater when Chapter 30 GI benefits were included. This report responds to request from the Subcommittee on Economic Opportunity, Committee on Veterans' Affairs…

  14. Combating Gangs: Better Coordination and Performance Measurement Would Help Clarify Roles of Federal Agencies and Strengthen Assessment of Efforts. Report to the Ranking Member, Committee on Oversight and Government Reform, House of Representatives. GAO-09-708

    Science.gov (United States)

    US Government Accountability Office, 2009

    2009-01-01

    The Department of Justice (DOJ) estimates that the United States has about a million gang members. While state and local agencies have primary responsibility for combating gang crime, the federal government has key roles to enforce laws and help fund programs to provide alternatives to gang membership for at-risk youth. GAO was asked to examine…

  15. [Gao Jingyi. Han yu yu bei Ou yu yan : Han yu yu Wula'er yu yan ji Yin Ou yu yan tong yuan tan jiu] / Ago Künnap

    Index Scriptorium Estoniae

    Künnap, Ago, 1941-

    2010-01-01

    Arvustus: Gao Jingyi. Han yu yu bei Ou yu yan : Han yu yu Wula'er yu yan ji Yin Ou yu yan tong yuan tan jiu = Chinese language and languages of northern Europe. Beijing : Zhongguo she hui ke xue chu ban she, 2008

  16. Opportunities to Reduce Fragmentation, Overlap, and Potential Duplication in Federal Teacher Quality and Employment and Training Programs. Testimony before the Committee on Education and the Workforce, House of Representatives. GAO-11-509T

    Science.gov (United States)

    Dodaro, Gene L.

    2011-01-01

    This testimony discusses US Government Accountability Office's (GAO's) recent report entitled "Opportunities to Reduce Potential Duplication in Government Programs, Save Tax Dollars, and Enhance Revenue." This report delineates dozens of areas across government where fragmentation, overlap, and potential duplication merit the attention of Congress…

  17. Magnetic transition anisotropies in orthorhombic LuMnO3 and HoMnO3 multiferroic thin films

    Science.gov (United States)

    Tsai, T. Y.; Lin, T. H.; Slowry, S.; Luo, C. W.; Wu, K. H.; Lin, J.-Y.; Uen, T. M.; Juang, J. Y.

    2010-01-01

    We have successfully prepared the b-axis-oriented orthorhombic LuMnO3 (LuMO) and HoMnO3 (HMO) thin films by pulsed laser deposition on (110)-LaAlO3 substrates. The nearly perfect alignment between the film growth orientation and the substrate allows us to study the magnetic transitions along the respective crystal orientation, which has displayed marked anisotropic behaviours. In particular, with the largest ionic size difference between Lu and Ho for the family of RMnO3 displaying the E-type AFM, the effects of lattice distortion on the magnetic transition are compared.

  18. 通肯酸浆的组织培养与植株再生%Tissue Culture and Plantlet Regeneration of Physalis tungkenensis Kuan et Gao

    Institute of Scientific and Technical Information of China (English)

    宗宪春; 许向阳; 王傲雪; 李景富

    2010-01-01

    @@ 1植物名称 通肯酸浆(Physalis tungkenensis Kuan et Gao). 2材料类别 无菌苗的子叶. 3培养条件 种子萌发培养基:MS基本培养基.愈伤组织诱导和分化培养基:(1)MS+6-BA 1.0 mg·L-1(单位下同)+IAA0.1;(2)MS+6-BA 1.0+IAA 0.2;(3)MS+6-BA 2.0+IAA0.1;(4)MS+6-BA 2.0+IAA 0.2;(5)MS+6-BA 3.0+IAA 0.2.

  19. 2010年鲁迅研究综述%A Summary of Studies of Lu Xun in 2010

    Institute of Scientific and Technical Information of China (English)

    崔云伟; 刘增人

    2011-01-01

    2010 saw a steady momentum in the field of research on Lu Xun. Fujii Shoz, Li Jin, Feng Guanglian and other scholars came up with very important viewpoints about Lu Xun' s fiction. The study of Wild Grass reached a new height, represented by a paper by Wang Weidong. Many original papers were published about Lu Xun' s essays. The study of his ideology is focused on the following topics: Lu Xun and contemporary China, Lu Xun and the Left-Wing Federation, Lu Xun and Enlightenment, Lu Xun and the May 4 Movement, Lu Xun and Realism, Lu Xun and radicalism, Lu Xun and Chinese and foreign culture, Lu Xun and existentialism, Lu Xun' s images of animals, studies of the reception of Lu Xun. There was also tremendous progress in research into Lu Xun' s life, the teaching of Lu Xun, Lu Xun' s viewpoints of fine arts, and the study of Lu Xun studies.%2010年鲁迅研究依然保持了持续发展的势头,在平淡从容中出现了诸多热点和亮点。藤井省三、李今、冯光廉皆对鲁迅小说发表了极为精彩的看法。《野草》研究又出现了一个新的高潮,汪卫东的文章堪称力作。鲁迅杂文研究收获颇丰,陈方竞、黄健、陈迪强、王学谦的阐释皆有其新颖独到之处。思想研究主要集中为十个专题:鲁迅与当代中国、鲁迅与左联、鲁迅与启蒙、鲁迅与五四、鲁迅与现实主义、鲁迅与激进主义、鲁迅与中外文化、鲁迅与存在主义、鲁迅笔下的动物意象、鲁迅的接受研究等,李新宇、阎真、杨义、王锡荣、刘家呜、王晓初、姜振昌、吕周聚、陈汉萍、吴康、靳新来、钱理群等的文章(专著)皆堪称优异之作。鲁迅生平和传记写作研究以周楠本、冯光廉的文章最为突出,且出现了一大批初版和再版的鲁迅传。鲁迅教学研究中张梦阳、冯光廉的论述最为引人注目。赵延年、崔云伟的鲁迅与美术研究,王富仁、贺仲明的鲁迅研究之研究皆能使人耳目一新。

  20. Gao Xing:A Speaker of Aphasiac in Sexual Distinction Perspective%《高兴》:性别视域下失语者的代言

    Institute of Scientific and Technical Information of China (English)

    于倩

    2014-01-01

    后殖民理论主将斯皮瓦克认为“底层人”既是社会弱势群体又是“不能说话”的哑言群体,他们只能作为失语者被代言。贾平凹的《高兴》就是失语者的代言,在有意为刘高兴等男性进城农民工真情代言的同时,在叙事方式及结构设计、女性形象塑造、语言运用等方面无意遮蔽了女性进城农民工的现实处境和话语权利,但也恰恰是有意的代言与无意的遮蔽揭示出了底层人,特别是女性生存状态的本质,把底层写作推向了新高度。%Spivak thinks that not only class is in the voiceless condition .As a result, They cannot speak themselves , and they must be represented by others .Jia Ping-wa’s Gao Xing is a novel about subaltern class---immigrant worker.While under sexual distinction perspective , the female workers are ignored at narrative pattern , image creation , language use , but that ’ s the real living condition about female workers , at this point, Gao Xing reached a new height .

  1. Effective lattice stabilization of gadolinium aluminate garnet (GdAG) via Lu3+ doping and development of highly efficient (Gd,Lu)AG:Eu3+ red phosphors

    OpenAIRE

    Jinkai Li, Ji-Guang Li, Zhongjie Zhang, Xiaoli Wu, Shaohong Liu, Xiaodong Li, Xudong Sun and Yoshio Sakka

    2012-01-01

    The metastable garnet lattice of Gd3Al5O12 is stabilized by doping with smaller Lu3+, which then allows an effective incorporation of larger Eu3+ activators. The [(Gd1−xLux)1−yEuy]3Al5O12 (x = 0.1–0.5, y = 0.01–0.09) garnet solid solutions, calcined from their precursors synthesized via carbonate coprecipitation, exhibit strong luminescence at 591 nm (the 5D0 → 7F1 magnetic dipole transition of Eu3+) upon UV excitation into the charge transfer band (CTB) at ∼239 nm, with CIE chromaticity coor...

  2. Analysis of heat capacity and Mössbauer data for LuZnSn2 compound

    Directory of Open Access Journals (Sweden)

    Łątka Kazimierz

    2015-03-01

    Full Text Available New analysis of heat capacity data is presented for LuZnSn2 compound that takes into account anharmonic effects together with the existence of Einstein modes. 119mSn Mössbauer spectroscopy was used to monitor the hyperfine parameters at the two crystallographically inequivalent Sn sites in the studied compound. The problem of non-unique mathematical resonance spectrum description and the problem how to choose physically meaningful set of hyperfine parameters will be thoroughly discussed. Measured quadrupole interaction constants by 119mSn Mössbauer spectroscopy give estimations for Vzz component of electric field gradient tensor at both Sn sites in LuZnSn2.

  3. High-energy, ceramic-disk Yb:LuAG laser amplifier.

    Science.gov (United States)

    Siebold, M; Loeser, M; Roeser, F; Seltmann, M; Harzendorf, G; Tsybin, I; Linke, S; Banerjee, S; Mason, P D; Phillips, P J; Ertel, K; Collier, J C; Schramm, U

    2012-09-24

    We report the first short-pulse amplification results to several hundred millijoule energies in ceramic Yb:LuAG. We have demonstrated ns-pulse output from a diode-pumped Yb:LuAG amplifier at a maximum energy of 580 mJ and a peak optical-to-optical efficiency of 28% at 550 mJ. In cavity dumped operation of a nanosecond oscillator we obtained 1 mJ at up to 100 Hz repetition rate. A gain bandwidth of 5.4 nm was achieved at room temperature by measuring the small-signal single-pass gain. Furthermore, we compared our results with Yb:YAG within the same amplifier system.

  4. Spin wave and spin flip in hexagonal LuMnO3 single crystal

    Science.gov (United States)

    Chen, Xiang-Bai; Guo, Peng-Cheng; Huyen, Nguyen Thi; Kim, Seung; Yang, In-Sang; Wang, Xueyun; Cheong, Sang-Wook

    2017-03-01

    Manipulation and control of spin wave and spin flip are crucial for future developments of magnonic and spintronic devices. We present that the spin wave in hexagonal LuMnO3 single crystal can be selectively excited with laser polarization perpendicular to the c-axis of hexagonal LuMnO3 and photon energy ˜1.8 eV. The selective excitation of spin wave also suggests that the spin flip can be selectively controlled in hexagonal manganites. In addition, a microscopic model of the spin wave generation correlated with the four-spin-flip in hexagonal manganites is suggested to account for the line-shape of the observed spin wave.

  5. Exchange effects on the electronic excitations in the optical spectrum of LuMnO_3

    Science.gov (United States)

    Drew, H. D.; Simpson, J. R.; Sushkov, A. B.; Romero, D. B.; Quijada, M.; Ahn, J. S.; Ishibashi, H.; Hur, N.; Cheong, S. W.; Millis, A. J.

    2003-03-01

    Hexagonal LuMnO3 is a multiferroic material with ferroelectric phase transition at 900 K and it becomes an antiferromagnet with a high degree of frustration at 90 K. We have measured the optical conductivity of single crystal LuMnO3 from 1 meV to 5.5 eV in E||c and E⊥ c polarizations at temperatures between 4 and 300 K. A symmetry allowed (E⊥ c) on-site d-d transition near 1.7 eV is observed to blue shift ( ˜0.15 eV) with an inflection point at TN in the antiferromagnetic state due to Mn-Mn exchange energy effects. Photoluminescence measurements reveal a Jahn-Teller splitting in the optical excited state. This work has been supported by the NSF-MRSEC at the University of Maryland, DMR 0080008.

  6. Quantum oscillation measurements of β-LuAlB{sub 4}

    Energy Technology Data Exchange (ETDEWEB)

    Reiss, Pascal; Baglo, Jordan; Chen, Xiaoye; Tan, HongEn; Sutherland, Michael; Grosche, F. Malte [Cavendish Laboratory, University of Cambridge, Cambridge (United Kingdom); Friedemann, Sven [HH Wills Laboratory, University of Bristol, Bristol (United Kingdom); Goh, Swee K. [Chinese University of Hong Kong, Shatin, N.T. (China); Kuga, Kentaro; Nakatsuji, Satoru [Institute for Solid State Physics, University of Tokyo, Kashiwa (Japan); Harima, Hisatomo [Department of Physics, Graduate School of Science, Kobe University, Kobe (Japan)

    2016-07-01

    The Yb-based heavy fermion superconductor β-YbAlB{sub 4} displays a quantum critical point without tuning by applied pressure, magnetic field, or doping, which has been attributed to an unusual renormalised band structure. Quantum oscillation measurements of the Fermi surface in β-YbAlB{sub 4} have so far proved inconclusive, motivating us to undertake a detailed study of the isostructural reference compound β-LuAlB{sub 4}, which in contrast to the Yb compound is characterised by a filled 4f shell. We present comprehensive results from rotation and mass studies in β-LuAlB{sub 4}, which broadly agree with band structure calculations and display moderate mass enhancements contrasting with the much larger enhancements seen in β-YbAlB{sub 4} - further emphasising the important contribution of f electrons to the itinerant electron physics of β-YbAlB{sub 4}.

  7. SuperLU{_}DIST: A scalable distributed-memory sparse direct solver for unsymmetric linear systems

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xiaoye S.; Demmel, James W.

    2002-03-27

    In this paper, we present the main algorithmic features in the software package SuperLU{_}DIST, a distributed-memory sparse direct solver for large sets of linear equations. We give in detail our parallelization strategies, with focus on scalability issues, and demonstrate the parallel performance and scalability on current machines. The solver is based on sparse Gaussian elimination, with an innovative static pivoting strategy proposed earlier by the authors. The main advantage of static pivoting over classical partial pivoting is that it permits a priori determination of data structures and communication pattern for sparse Gaussian elimination, which makes it more scalable on distributed memory machines. Based on this a priori knowledge, we designed highly parallel and scalable algorithms for both LU decomposition and triangular solve and we show that they are suitable for large-scale distributed memory machines.

  8. Transculturation of Madness: The Double Origin of Lu Xun's "Diary of a Madman".

    Science.gov (United States)

    Ma, Xiaolu

    2015-01-01

    Over the years scholars have examined the allegorical features of the depiction of madness in Lu Xun's "Diary of a Madman," yet to date little research has taken into consideration the intercultural angle embedded in the narrative's intersection of three cultures, namely Russian, Japanese and Chinese. This paper traces the European-Japanese-Sino route of modern neologisms of madness to explore the introduction of such neologisms into the modern Chinese language and how it corresponds with changing patterns of knowledge and power. I use my study of transculturation on the macro scale to frame a reexamination of the lexicon in "Diary of a Madman." I focus especially on kuangren and pohaikuang, the two key words employed by Lu Xun, to see how they contribute to the ambiguity in his attitude towards the power struggle between the East and the West, the old and the new.

  9. Photon strength functions in 177Lu: Study of scissors resonance in high-spin region

    Directory of Open Access Journals (Sweden)

    Bečvář F.

    2015-01-01

    Full Text Available The nucleus 177Lu is characteristic by an unusually high value of the thermal-neutron capturing state spin, J = 13/2, and by distinct low-energy rotational bands built on the 7/2+ ground state and the 9/2− level at 150 keV. The γ cascades connecting the capturing state with the members of these bands carry unique information about the role of identical M1 scissors-mode resonances, built according to Brink hypothesis assumingly on each energy level, even in conditions of fast nuclear rotation. With this motivation we measured a set of spectra of two-step γ cascades following the thermal neutron capture in 176Lu. The measurement was performed at neutron beam of the LWR-15 Reactor in Řež. From the analysis of these spectra the common parameters of the scissors resonances were deduced. The obtained results are discussed.

  10. Electronic Raman scattering and the renormalization of the electron spectrum in LuB{sub 12}

    Energy Technology Data Exchange (ETDEWEB)

    Ponosov, Yu. S., E-mail: ponosov@imp.uran.ru; Streltsov, S. V., E-mail: streltsov@gmail.com [Russian Academy of Sciences, Institute of Metal Physics, Ural Branch (Russian Federation); Levchenko, A. V.; Filippov, V. B. [National Academy of Sciences of Ukraine, Frantsevich Institute of Materials Science Problems (Ukraine)

    2016-09-15

    The electronic Raman scattering in LuB{sub 12} single crystals of various isotope compositions is studied in the temperature range 10–650 K. The shape and the energy position of spectral maxima depend on the direction and magnitude of a probe wavevector, the temperature, and the excitation symmetry and remain unchanged when the isotope composition changes. Experimental spectra are compared with the spectra simulated on the basis of a calculated electronic structure. The experimental results are successfully described when the electron spectrum renormalization effects caused by electron–phonon coupling are taken into account. This confirms that the origin of the observed spectra in LuB{sub 12} is due to Raman scattering by electrons. A comparison of the calculated and experimental data makes it possible to determine the coupling constant (λ{sub ep} = 0.32) that gives the correct superconducting transition temperature.

  11. Coexisting wobbling and quasiparticle excitations in the triaxial potential well of {sup 163}Lu

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, D.R.; Hagemann, G.B.; Herskind, B.; Sletten, G.; Wilson, J.N. [Niels Bohr Institute, Blegdamsvej 17, DK-2100, Copenhagen (Denmark); Hamamoto, I. [Niels Bohr Institute, Blegdamsvej 17, DK-2100, Copenhagen (Denmark); Department of Mathematical Physics, LTH, University of Lund, Lund (Sweden); Oedegaard, S.W. [Department of Physics, University of Oslo, PB 1048 Blindern, N-0316, Oslo (Norway); Spohr, K. [Department of Electronic Engineering and Physics, University of Paisley (United Kingdom); Huebel, H.; Bringel, P.; Neusser, A.; Schoenwasser, G.; Singh, A.K. [Helmholtz-Institut fuer Strahlen- und Kernphysik, University of Bonn, Nussallee 14-16, D-53115, Bonn (Germany); Ma, W.C.; Amro, H. [Mississippi State University, MS 39762, Mississippi State (United States); Bracco, A.; Leoni, S.; Benzoni, G. [Dipartimento di Fisica and INFN, Sezione di Milano, Milano (Italy); Maj, A. [Niewodniczanski Insitute of Nuclear Physics, Krakow (Poland); Petrache, C.M. [Dipartimento di Fisica and INFN, Sezione di Padova, Padova (Italy); Dipartimento di Matematica e Fisica, Universita di Camerino, Camerino (Italy); Lo Bianco, G.; Bednarczyk, P.; Curien, D.

    2004-02-01

    High-spin states of the nucleus {sup 163}Lu have been populated through the fusion-evaporation reaction {sup 139}La({sup 29}Si,5n) with a beam energy of 157 MeV. In addition to the two lowest excited triaxial strongly deformed (TSD) bands, recently interpreted as one- and two-phonon wobbling excitations, a third excited TSD band has been firmly established decaying to the yrast TSD band. The assignment of this band as a three-quasiparticle band shows together with the normal deformed (ND) level scheme the presence not only of shape coexistence between ND and TSD structures, but also an interplay of wobbling and quasiparticle excitations in the triaxial strongly deformed potential well of {sup 163}Lu. (orig.)

  12. Experimental evaluation and thermodynamic assessment of the LiF-LuF{sub 3} phase diagram

    Energy Technology Data Exchange (ETDEWEB)

    Santos, I.A. dos [Instituto de Pesquisas Energeticas e Nucleares, CP 11049, Butanta 05422-970, Sao Paulo, SP (Brazil); Klimm, D. [Leibniz Institute for Crystal Growth, Max-Born-Strasse 2, 12489 Berlin (Germany); Baldochi, S.L.; Ranieri, I.M. [Instituto de Pesquisas Energeticas e Nucleares, CP 11049, Butanta 05422-970, Sao Paulo, SP (Brazil)

    2013-01-20

    The phase diagram of the system LiF-LuF{sub 3} has been revised using thermal analysis. Specific heat capacity and enthalpy of phase transition and fusion were measured by differential scanning calorimetry for all compounds belonging to the system. A thermodynamic optimization of the LiF-LuF{sub 3} phase diagram was performed by fitting the Gibbs energy functions to the experimental data that were taken from the literature or measured in this work. Excess energy terms, which describe the effect of interaction between the two fluoride compounds in the liquid solution, were expressed by the Redlich-Kister polynomial function. The assessed phase diagram was in suitable agreement with the re-evaluated experimental data.

  13. Preparation and Characterization of {sup 177}Lu Labeled Antibody against Tyrosine Kinase Receptor Her2

    Energy Technology Data Exchange (ETDEWEB)

    Lee, So-Young; Hong, Young-Don; Choi, Sun-Ju [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2008-05-15

    The tyrosine kinase receptor Her2, also known in humans as erbB2, is a member of the epidermal growth factor receptor (EGFR or erbB1) family. The Her2 is highly expressed in many cancer types and over expressed in approximately 30% of all primary breast cancer. Overexpression of Her2 is associated with a poor prognosis. Her2 is a suitable target because it involves an extracellular domain that can be targeted by antibodies produced by B cells. Based on these advantages, we tried to prepare the {sup 177}Lu labeled Her2 antibody. This radioimmunoconjugate could act by not only blocking the Her2 signalling pathway using antibody but also killing the tumour cell using {beta} energy of {sup 177}Lu.

  14. Hexagonal frustrated RMnO3 manganites (R = Y, Lu) under high pressure

    Science.gov (United States)

    Kozlenko, D. P.; Kichanov, S. E.; Lee, S.; Park, J.-G.; Glazkov, V. P.; Savenko, B. N.

    2007-05-01

    The crystalline and magnetic structures of YMnO3 and LuMnO3 hexagonal manganites under pressures of 0 6 GPa and in the temperature range 10 295 K have been investigated by neutron diffraction. Application of pressure leads to a significant decrease in the ordered magnetic moment of Mn ions (at T = 10 K) from 3.27 (0 GPa) to 1.52 μB (5 GPa) for YMnO3 and from 2.48 (0 GPa) to 1.98 μB (6 GPa) for LuMnO3. Under high pressures, spin reorientation of Mn magnetic moments and a change in the symmetry of the antiferromagnetic structure are observed in YMnO3. The relationship between the triangular lattice distortion parameter and the symmetry of the triangular antiferromagnetic state of RMnO3 hexagonal manganites is discussed.

  15. Effects of Phase Composition on Microstructure and Mechanical Properties of Lu2O3-doped Porous Silicon Nitride Ceramics

    Institute of Scientific and Technical Information of China (English)

    Quan Li; Xiaowei Yin

    2011-01-01

    Porous silicon nitride ceramics (Si3N4) were fabricated by pressureless sintering using different particle size of silicon nitride powder. Lu2O3 was used as sintering additive. According to phase relationships in the ternary system Si3N4-SiO2-Lu2O3, porous Si3N4 ceramics with different phase composition were designed through the change of the content of SiO2 which was formed by the oxidation at 800℃ in air. Porous Si3N4 with different phase compositions was obtained after sintering at 1800℃in N2atmosphere. A small content of SiO2 favored the formation of secondary phase Lu4Si2O7N2, while large content of SiO2 favored the formation of secondary phase Lu2Si2O7 and Si2N2O. Porous Si3N4 ceramics with secondary phase Lu4Si2O7N2 had a flexural strength of 207 MPa, while that with secondary phase Si2N2O and Lu2Si2O7 had lower flexural strength.

  16. Spin-lattice coupling and frustrated magnetism in Fe-doped hexagonal LuMnO3

    Science.gov (United States)

    Nair, Harikrishnan S.; Fu, Zhendong; Kumar, C. M. N.; Pomjakushin, V. Y.; Xiao, Yinguo; Chatterji, Tapan; Strydom, André M.

    2015-05-01

    Strong spin-lattice coupling and prominent frustration effects observed in the 50% Fe-doped frustrated hexagonal (h)\\text{LuMnO}3 are reported. A Néel transition at T{N}≈112 \\text{K} and a possible spin re-orientation transition at T{SR}≈55 \\text{K} are observed in the magnetization data. From neutron powder diffraction data, the nuclear structure at and below 300 K was refined in polar P63cm space group. While the magnetic structure of LuMnO3 belongs to the Γ4 (P6'_3c'm) representation, that of LuFe0.5Mn0.5O3 belongs to Γ1 (P6_3cm) which is supported by the strong intensity for the (100) reflection and also judging by the presence of spin-lattice coupling. The refined atomic positions for Lu and Mn/Fe indicate significant atomic displacements at T{N} and T{SR} which confirms strong spin-lattice coupling. Our results complement the discovery of room temperature multiferroicity in thin films of h\\text{LuFeO}3 and would give impetus to study LuFe1-x Mn x O3 systems as potential multiferroics where electric polarization is linked to giant atomic displacements.

  17. Effect of Li+ ions co-doping on luminescence, scintillation properties and defects characteristics of LuAG:Ce ceramics

    Science.gov (United States)

    Liu, Shuping; Feng, Xiqi; Mares, Jiri A.; Babin, Vladimir; Hu, Chen; Kou, Huamin; D'Ambrosio, Carmelo; Li, Jiang; Pan, Yubai; Nikl, Martin

    2017-02-01

    Monovalent Li+ codoped Lu3Al5O12:Ce (LuAG:Ce) optical ceramics were fabricated by solid state reaction method and further optimized by an air-annealing process. Optical absorption, radioluminescence spectra and scintillation properties such as light yield, scintillation decay times and afterglow were measured and compared with those of the Li+ free LuAG:Ce ceramic and the commercial LuAG:Ce single crystal samples. Positive effect of Li+ codopant consists mainly in the significant increase of scintillation light yield, acceleration of scintillation decay as well as the decrease of afterglow intensity. With 0.3% Li codoping, the obtained LuAG:Ce,Li ceramic displays a light yield of ∼29200 ph/MeV at 10 μs shaping time, higher than that of the LuAG:Ce single crystal and optical ceramic scintillators ever reported. The partial conversion of the stable Ce3+ to Ce4+ centers and the shallow and deep traps effect suppression by the Li+ codoping are discussed.

  18. HORSE, WOMEN, WEAPON IN THE EPIC OF KÖROĞLU / KÖROĞLU DESTANI’NDA AT, KADIN, SİLAH

    Directory of Open Access Journals (Sweden)

    Mehmet Emin BARS (M.A.H.

    2008-05-01

    Full Text Available The epic of Köroğlu is one of the most loved epics whichreaches today from long centuries and stil keeps its place ofimportance in narration tradition. Đt is an epical work that leftdeep influences over Turkish world and over nations livedtogether with Turks for long centuries. Đt is a monument,binding the past and the present. Even today when taken intoconsideration of the wideness of its narreted and listenedgeographical area its importance from the view of maintainingthe cultural integrity between Turks will be understood muchbeter. Đt is difficult to come across such a work whichmaintains its vitality and dynamism with a wide performancearea in the lives of other nations. The perfection and thereachment of education level in Turkish epic tradition are thefactors which cause this result. Đn our writing the concepts ofhorse, woman and weapon which take place in Turkomanvariant of Köroğlu will be discussed.

  19. Efficient femtosecond high power Yb:Lu(2)O(3) thin disk laser.

    Science.gov (United States)

    Marchese, S V; Baer, C R E; Peters, R; Kränkel, C; Engqvist, A G; Golling, M; Maas, D J H C; Petermann, K; Südmeyer, T; Huber, G; Keller, U

    2007-12-10

    We demonstrate the first passively mode-locked thin disk laser based on Yb:Lu(2)O(3). The laser generates 370-fs pulses with 20.5 W of average power in a diffraction-limited beam (M(2) pump power of 56 W, resulting in an optical-to-optical efficiency of 43%, which is higher than for any previously mode-locked thin disk laser.

  20. Probability and Statistics——in Honor of Pao-Lu Hsu's 100th Birthday

    Institute of Scientific and Technical Information of China (English)

    Dayue CHEN; Zhi GENG; Zhi-Ming MA

    2011-01-01

    Professor Pao-Lu Hsu (1910-1970) was the pioneer and founding father of Probability and Statistics in China.His research work ranged from limit theory,statistical inference,multivariate analysis,to random matrices and other related topics,and were well recognized by his peers.He was the first Chinese probabilist/statistician with the world fame,though many of his papers were written in Chinese and were published in Chinese journals.

  1. First principle calculation of structure and lattice dynamics of Lu2Si2O7

    Science.gov (United States)

    Nazipov, D. V.; Nikiforov, A. E.

    2016-12-01

    Ab initio calculations of crystal structure and Raman spectra has been performed for single crystal of lutetium pyrosilicate Lu2Si2O7. The types of fundamental vibrations, their frequencies and intensities in the Raman spectrum has been obtained for two polarizations. Calculations were made in the framework of density functional theory (DFT) with hybrid functionals. The isotopic substitution was calculated for all inequivalent ions in cell. The results in a good agreement with experimental data.

  2. LU分解的增长因子%ON GROWTH FACTORS OF THE LU FACTORIZATION

    Institute of Scientific and Technical Information of China (English)

    魏木生; 刘巧华

    2008-01-01

    In this article, we derive upper bounds of different growth factors for the LU factorization, which are dominated by A11(k)-1A12(k),A21(k)A11(k)-1, where A11(k), A12(k), A21(k), A22(k) are sub-matrices of A. We also derive upper bounds of growth factors for the Cholesky factorization. Numerical examples are presented to verify our findings.

  3. Bien écrire en affaires savoir rédiger pour être lu et convaincre

    CERN Document Server

    Berrou, Jean-Paul

    1991-01-01

    Ce qu'il faut savoir pour bien rédiger ses écrits professionnels au travers d'une démarche méthodique pour bien organiser sa pensée en vue d'écrire efficacement, de conseils et de techniques pour être compris à coup sûr et être lu jusqu'au bout avec intérêt. Agrémenté de nombreux exemples concrets.

  4. Quantitative (177)Lu SPECT imaging using advanced correction algorithms in non-reference geometry.

    Science.gov (United States)

    D'Arienzo, M; Cozzella, M L; Fazio, A; De Felice, P; Iaccarino, G; D'Andrea, M; Ungania, S; Cazzato, M; Schmidt, K; Kimiaei, S; Strigari, L

    2016-12-01

    Peptide receptor therapy with (177)Lu-labelled somatostatin analogues is a promising tool in the management of patients with inoperable or metastasized neuroendocrine tumours. The aim of this work was to perform accurate activity quantification of (177)Lu in complex anthropomorphic geometry using advanced correction algorithms. Acquisitions were performed on the higher (177)Lu photopeak (208keV) using a Philips IRIX gamma camera provided with medium-energy collimators. System calibration was performed using a 16mL Jaszczak sphere surrounded by non-radioactive water. Attenuation correction was performed using μ-maps derived from CT data, while scatter and septal penetration corrections were performed using the transmission-dependent convolution-subtraction method. SPECT acquisitions were finally corrected for dead time and partial volume effects. Image analysis was performed using the commercial QSPECT software. The quantitative SPECT approach was validated on an anthropomorphic phantom provided with a home-made insert simulating a hepatic lesion. Quantitative accuracy was studied using three tumour-to-background activity concentration ratios (6:1, 9:1, 14:1). For all acquisitions, the recovered total activity was within 12% of the calibrated activity both in the background region and in the tumour. Using a 6:1 tumour-to-background ratio the recovered total activity was within 2% in the tumour and within 5% in the background. Partial volume effects, if not properly accounted for, can lead to significant activity underestimations in clinical conditions. In conclusion, accurate activity quantification of (177)Lu can be obtained if activity measurements are performed with equipment traceable to primary standards, advanced correction algorithms are used and acquisitions are performed at the 208keV photopeak using medium-energy collimators.

  5. Neutron capture measurement on {sup 173}Lu at LANSCE with DANCE detector

    Energy Technology Data Exchange (ETDEWEB)

    Theroine, C.; Ebran, A.; Meot, V.; Roig, O. [CEA DAM DIF, F-91297 Arpajon (France); Bond, E. M.; Bredeweg, T. A.; Couture, A.; Haight, R. C.; Jandel, M.; Nortier, F. M.; O' Donnell, J. M.; Rundberg, R. S.; Taylor, W. A.; Ullmann, J. L.; Viera, D. J.; Wilhelmy, J. B.; Wouters, J. M. [Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States)

    2013-06-10

    The (n,{gamma}) cross section on the unstable {sup 173}Lu(t{sub 1/2} = 1.37y) has been measured from thermal energy up to 200 eV at Los Alamos Neutron Science Center (LANSCE) with The Detector for Advanced Neutron Capture Experiements (DANCE). The main aim of this study is to validate and optimize reaction models for unstable nucleus. A preliminary capture yield will be presented in this paper.

  6. Neutron capture measurement on 173Lu at LANSCE with DANCE detector

    Science.gov (United States)

    Theroine, C.; Ebran, A.; Méot, V.; Roig, O.; Bond, E. M.; Bredeweg, T. A.; Couture, A.; Haight, R. C.; Jandel, M.; Nortier, F. M.; O'Donnell, J. M.; Rundberg, R. S.; Taylor, W. A.; Ullmann, J. L.; Viera, D. J.; Wilhelmy, J. B.; Wouters, J. M.

    2013-06-01

    The (n,γ) cross section on the unstable 173Lu(t1/2 = 1.37y) has been measured from thermal energy up to 200 eV at Los Alamos Neutron Science Center (LANSCE) with The Detector for Advanced Neutron Capture Experiements (DANCE). The main aim of this study is to validate and optimize reaction models for unstable nucleus. A preliminary capture yield will be presented in this paper.

  7. Implementation of BT, SP, LU, and FT of NAS Parallel Benchmarks in Java

    Science.gov (United States)

    Schultz, Matthew; Frumkin, Michael; Jin, Hao-Qiang; Yan, Jerry

    2000-01-01

    A number of Java features make it an attractive but a debatable choice for High Performance Computing. We have implemented benchmarks working on single structured grid BT,SP,LU and FT in Java. The performance and scalability of the Java code shows that a significant improvement in Java compiler technology and in Java thread implementation are necessary for Java to compete with Fortran in HPC applications.

  8. Measurement of conversion coefficients in normal and triaxial strongly deformed bands in {sup 167}Lu.

    Energy Technology Data Exchange (ETDEWEB)

    Gurdal, G.; Beausang, C. W.; Brenner, D. S.; Ai, H.; Casten, R. F.; Crider, B.; Heinz, A.; Williams, E.; Hartley, D. J.; Carpenter, M. P.; Hecht, A. A.; Janssens, R. V. F.; Lauritsen, T.; Lister, C. J.; Raabe, R.; Seweryniak, D.; Zhu, S.; Saladin, J. X.; Physics; Yale Univ.; Clark Univ.; Univ. of Richmond; United States Naval Academy; Univ. of Maryland; Univ. of Pittsburgh

    2008-01-01

    Internal conversion coefficients have been measured for transitions in both normal deformed and triaxial strongly deformed bands in {sup 167}Lu using the Gammasphere and ICE Ball spectrometers. The results for all in-band transitions are consistent with E2 multipolarity. Upper limits are determined for the internal conversion coefficients for linking transitions between TSD Band 2 and TSD Band 1, the n{sub w} = 1 and n{sub w} = 0 wobbling bands, respectively.

  9. Achieving numerical accuracy and high performance using recursive tile LU factorization with partial pivoting

    KAUST Repository

    Dongarra, Jack

    2013-09-18

    The LU factorization is an important numerical algorithm for solving systems of linear equations in science and engineering and is a characteristic of many dense linear algebra computations. For example, it has become the de facto numerical algorithm implemented within the LINPACK benchmark to rank the most powerful supercomputers in the world, collected by the TOP500 website. Multicore processors continue to present challenges to the development of fast and robust numerical software due to the increasing levels of hardware parallelism and widening gap between core and memory speeds. In this context, the difficulty in developing new algorithms for the scientific community resides in the combination of two goals: achieving high performance while maintaining the accuracy of the numerical algorithm. This paper proposes a new approach for computing the LU factorization in parallel on multicore architectures, which not only improves the overall performance but also sustains the numerical quality of the standard LU factorization algorithm with partial pivoting. While the update of the trailing submatrix is computationally intensive and highly parallel, the inherently problematic portion of the LU factorization is the panel factorization due to its memory-bound characteristic as well as the atomicity of selecting the appropriate pivots. Our approach uses a parallel fine-grained recursive formulation of the panel factorization step and implements the update of the trailing submatrix with the tile algorithm. Based on conflict-free partitioning of the data and lockless synchronization mechanisms, our implementation lets the overall computation flow naturally without contention. The dynamic runtime system called QUARK is then able to schedule tasks with heterogeneous granularities and to transparently introduce algorithmic lookahead. The performance results of our implementation are competitive compared to the currently available software packages and libraries. For example

  10. First principle calculation of structure and lattice dynamics of Lu2Si2O7

    Directory of Open Access Journals (Sweden)

    Nazipov D.V.

    2017-01-01

    Full Text Available Ab initio calculations of crystal structure and Raman spectra has been performed for single crystal of lutetium pyrosilicate Lu2Si2O7. The types of fundamental vibrations, their frequencies and intensities in the Raman spectrum has been obtained for two polarizations. Calculations were made in the framework of density functional theory (DFT with hybrid functionals. The isotopic substitution was calculated for all inequivalent ions in cell. The results in a good agreement with experimental data.

  11. The 4f-5d luminescence transitions in cerium-doped LuF3

    Science.gov (United States)

    Guerbous, L.; Krachni, O.

    Emission and excitation spectra of the Ce3+ ion in LuF3 single crystal were measured at 77 K. The broad bands observed in these spectra were attributed to the parity-allowed electric-dipole 4f ← 5d transitions within Ce3+ ion. No zero-phonon lines were observed, which is indicative of a strong electron-phonon coupling in this host. It is shown that Ce3+ 5d excited configuration splits into five crystal-field components in LuF3. The influence of the crystalline environment on the position of the lowest Ce3+ 5d level is investigated. The energy of the lowest level of the 4fN-15d excited configuration was predicted for all the trivalent rare earth ions embedded in LuF3. Positions of crystal field spitting levels of 4fN-15d configuration relative to the host electronic bands were discussed.

  12. Angle-dependent magnetoresistance and quantum oscillations in high-mobility semimetal LuPtBi

    KAUST Repository

    Xu, Guizhou

    2017-03-14

    The recent discovery of ultrahigh mobility and large positive magnetoresistance in topologically non-trivial Half-Heusler semimetal LuPtBi provides a unique playground for studying exotic physics and significant perspective for device applications. As an fcc-structured electron-hole-compensated semimetal, LuPtBi theoretically exhibits six symmetrically arranged anisotropic electron Fermi pockets and two nearly-spherical hole pockets, offering the opportunity to explore the physics of Fermi surface with a simple angle-related magnetotransport properties. In this work, through the angle-dependent transverse magnetoresistance measurements, in combination with high-field SdH quantum oscillations, we achieved to map out a Fermi surface with six anisotropic pockets in the high-temperature and low-field regime, and furthermore, identify a possible magnetic field driven Fermi surface change at lower temperatures. Reasons account for the Fermi surface change in LuPtBi are discussed in terms of the field-induced electron evacuation due to Landau quantization.

  13. Geochronology of the volcanic rocks in the Lu-Zong basin and its significance

    Institute of Scientific and Technical Information of China (English)

    David; COOKE; Sebastien; MEFFRE

    2008-01-01

    The Lu-Zong (Lujiang-Zongyang) basin is one of the most important volcanic basins in the middle and lower reaches of the Yangtze River area, China. It comprises four shoshonitic volcanic units, which are, in an ascending order, the Longmenyuan, Zhuanqiao, Shuangmiao and Fushan Groups. The LA-ICP MS U-Pb zircon ages of the four units are: 134.8±1.8 Ma for the Longmenyuan Group, 134.1±1.6 Ma for the Zhuanqiao Group, 130.5±0.8 Ma for the Shuangmiao Group, and 127.1±1.2 Ma for the Fushan Group. The results indicate that all volcanic rocks in the Lu-Zong basin were formed in the Early Cretaceous from about 135 Ma to 127 Ma, lasting 8-10 Ma. There were no Jurassic volcanic activities in all the volcanic basins including the Lu-Zong basin in the middle and lower reaches of the Yangtze River area. This work has provided new chronological results for the further study and understanding of the tec- tonic, magmatic and metallogenic processes of eastern China in the Mesozoic.

  14. Enhanced Multiferroicity in LuFeO3 Through Sc Doping

    Science.gov (United States)

    Disseler, Steven; Oh, Yoon Seok; Hu, Rongwei; Luo, Xuan; Lynn, Jeff; Cheong, Sang-Wook; Ratcliff, William

    2015-03-01

    Hexagonal manganites of the type RMnO3 are well known examples of single-phase multiferroic materials, but suffer from low magnetic ordering temperatures and weak magnetoelectric coupling making them unsuitable for implementation in devices. Recently, the isostructural ferrites RFeO3 have been proposed as promising materials to exhibit greatly enhanced magnetic properties, including a much stronger coupling mechanism between ferromagnetic moment and ferroelectic polarization. Here we present a magnetometry and neutron scattering investigation of LuFeO3 forced into the ferroelectric structure through Sc-doping. We find the magnetic ordering temperature dramatically increases relative to pure hexagonal LuFeO3 and LuMnO3, as well as an unusual spin-reorientation at low temperatures. We will discuss possible mechanisms for this reorientation and how it provides insight into the enhanced magnetic properties Limit of the RFeO3 series. Supported in part by DOE Grant No. DE-FG02-07ER46382.

  15. Critical magnetic scattering in geometric frastrated multiferroic LuMnO3

    Science.gov (United States)

    Yano, Shinichiro; Li, Bing; Louca, Despina; Qiu, Yiming; Copley, John

    2013-03-01

    The coexistence of competing order parameters in the class of materials referred to as the multiferroics is of great interest. The hexagonal manganites AMnO3 (A = Y, Lu, Ho and Yb) with the P63cm space group exhibit a ferroelectric transition, at very high temperatures, typically ~ 1000 K, while the antiferromagnetic transition, TN, occurs at ~ 100K. Earlier studies on YMnO3 and LuMnO3 using neutron scattering on single crystals showed that diffuse scattering is present around the forbidden nuclear (100) Bragg peak which corresponds to Q=1.20 Å-1.Its intensity rises very sharply and drops just around TN. We performed inelastic neutron scattering measurement on a powder sample of LuMnO3 form 4 to 250 K using the DCS at NIST. Strong inelastic intensity, not due to magnon excitations, is observed at Q=1.32 and 2.50 Å-1. With cooling, the intensity gradually rises and reaches a peak around 100 K. Below, it drops drastically once the system orders. This kind of scattering is due to critical scattering arising from magnetic fluctuations above TN. The S(Q, ω) is asymmetric suggesting that the Mn spin correlations are mosmost likely 2-dimensional in nature.

  16. E -type noncollinear magnetic ordering in multiferroic o -LuMnO3

    Science.gov (United States)

    Mukherjee, Saumya; Dönni, Andreas; Nakajima, Taro; Mitsuda, Setsuo; Tachibana, Makoto; Kitazawa, Hideaki; Pomjakushin, Vladimir; Keller, Lukas; Niedermayer, Christof; Scaramucci, Andrea; Kenzelmann, Michel

    2017-03-01

    Multiferroic orthorhombic o -LuMnO3 exhibits large ferroelectric polarization induced by an E -type magnetic order. Recently, the E -type magnetic phase in LuMnO3 was proposed to feature magnetic moments tilted away from the collinear ordering. We employed neutron diffraction to determine the symmetry of the magnetic order in o -LuMnO3 . We observed that below TN=39 K, the Mn3 + spins order into an incommensurate amplitude-modulated phase that obeys the Pbnm crystal symmetry and is paraelectric. The incommensurate phase locks into a commensurate phase at TC=35.5 K described by a fully antiferromagnetic and noncollinear E -type order. This noncollinear E -type ordering breaks the spatial inversion symmetry and induces a spontaneous polarization at TC. At T =2 K, an appreciably large electric polarization was observed similar to that of other orthorhombic manganites featuring E -type magnetic order. We also present a Pbnm symmetry-allowed Dzyaloshinskii-Moriya interaction that explains the noncollinear E -type order in the commensurate phase. These results are in qualitative agreement with the type of distortions from collinear E -type antiferromagnetic order found using Monte Carlo simulation for rare-earth manganites [M. Mochizuki et al., Phys. Rev. B 84, 144409 (2011), 10.1103/PhysRevB.84.144409].

  17. On the photoelectron velocity-map imaging of lutetium monoxide anion LuO(-).

    Science.gov (United States)

    Liu, Zhiling; Xie, Hua; Li, Quanjiang; Qin, Zhengbo; Cong, Ran; Wu, Xia; Tang, Zichao; Fan, Hongjun

    2014-01-21

    We report a combined photoelectron velocity-map imaging spectroscopy and density functional theory investigation on lutetium monoxide anion. Transition between the X (1)Σ(+) anion electronic ground state and the neutral X (2)Σ(+) electronic ground state is observed. Vibrationally resolved spectra were obtained at four different photon energies, providing a wealth of spectroscopic information for the electronic ground states of the anionic lutetium monoxide and corresponding neutral species. Franck-Condon simulations of the ground-state transition are performed to assign vibrational structure in the spectra and to assist in identifying the observed spectral bands. The electronic ground state of LuO(-) is found to have a vibrational frequency of 743 ± 10 cm(-1) and an equilibrium bond length of 1.841 Å. The electron affinity of LuO is measured to be 1.624 ± 0.002 eV. The fundamental frequency of ground-state LuO is estimated to be 839 ± 10 cm(-1).

  18. Intrinsic energy resolution and light output of the $Lu_{07}Y_{03}$ AP:Ce scintillator

    CERN Document Server

    Kuntner, C; Lecoq, P; Pizzolotto, C; Schneegans, M

    2002-01-01

    Light output and energy resolution for a 2*2*10 mm/sup 3/ LuYAP:Ce crystal coupled to a XP2020Q photomultiplier were studied. The measured light output of 8530 photons/MeV includes the correction for the quantum efficiency of the XP2020Q photomultiplier. An energy resolution of 7.33% was obtained for 662 keV gamma -rays with a long face coupled to the PMT. The measured number of 2130 phe/MeV implies a photoelectron statistical contribution of 6.59% and hence a LuYAP intrinsic energy resolution of 3.21%. The relative light output of the LuYAP scintillator measured for photon energies varying from 31 keV to 1.333 MeV was constant within 7%. These observations are consistent with results for the YAP:Ce scintillator, and with the assumption that there is a direct correlation between the energy resolution of scintillators and non-proportionality of their light output versus energy in the low-energy domain. The results are compared to the relative light output of the LSO:Ce scintillator measured for varying energie...

  19. An In-Depth Analysis of the Chung-Lu Model

    Energy Technology Data Exchange (ETDEWEB)

    Winlaw, M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); DeSterck, H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Sanders, G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-10-28

    In the classic Erd}os R enyi random graph model [5] each edge is chosen with uniform probability and the degree distribution is binomial, limiting the number of graphs that can be modeled using the Erd}os R enyi framework [10]. The Chung-Lu model [1, 2, 3] is an extension of the Erd}os R enyi model that allows for more general degree distributions. The probability of each edge is no longer uniform and is a function of a user-supplied degree sequence, which by design is the expected degree sequence of the model. This property makes it an easy model to work with theoretically and since the Chung-Lu model is a special case of a random graph model with a given degree sequence, many of its properties are well known and have been studied extensively [2, 3, 13, 8, 9]. It is also an attractive null model for many real-world networks, particularly those with power-law degree distributions and it is sometimes used as a benchmark for comparison with other graph generators despite some of its limitations [12, 11]. We know for example, that the average clustering coe cient is too low relative to most real world networks. As well, measures of a nity are also too low relative to most real-world networks of interest. However, despite these limitations or perhaps because of them, the Chung-Lu model provides a basis for comparing new graph models.

  20. A comparison of SuperLU solvers on the intel MIC architecture

    Science.gov (United States)

    Tuncel, Mehmet; Duran, Ahmet; Celebi, M. Serdar; Akaydin, Bora; Topkaya, Figen O.

    2016-10-01

    In many science and engineering applications, problems may result in solving a sparse linear system AX=B. For example, SuperLU_MCDT, a linear solver, was used for the large penta-diagonal matrices for 2D problems and hepta-diagonal matrices for 3D problems, coming from the incompressible blood flow simulation (see [1]). It is important to test the status and potential improvements of state-of-the-art solvers on new technologies. In this work, sequential, multithreaded and distributed versions of SuperLU solvers (see [2]) are examined on the Intel Xeon Phi coprocessors using offload programming model at the EURORA cluster of CINECA in Italy. We consider a portfolio of test matrices containing patterned matrices from UFMM ([3]) and randomly located matrices. This architecture can benefit from high parallelism and large vectors. We find that the sequential SuperLU benefited up to 45 % performance improvement from the offload programming depending on the sparse matrix type and the size of transferred and processed data.

  1. Crystal-field analysis of Eu sup 3 sup + in Lu sub 2 O sub 3

    CERN Document Server

    Karbowiak, M; Hoelsae, J

    2003-01-01

    Low temperature (7 K) absorption spectra of polycrystalline sintered ceramic Lu sub 2 O sub 3 :Eu sup 3 sup + were recorded between 3950 and 50000 cm sup - sup 1. There are two different intrinsic Eu sup 3 sup + sites, C sub 2 and S sub 6 (C sub 3 sub i), in this host. A total of 105 crystal-field (CF) energy levels were assigned and fitted to a semiempirical Hamiltonian representing the combined free-ion (FI) and CF interactions for a 4f sup 6 ion in the C sub 2 symmetry site. 10 FI and 14 CF parameters were varied simultaneously in the least square adjustments yielding an rms deviation between the calculated and experimental levels of 15 cm sup - sup 1. The CF strength parameter, S, obtained from calculated B sub q sup k parameters is larger for Lu sub 2 O sub 3 when compared to the Y sub 2 O sub 3 host, which is in accordance with the smaller ionic radius of the Lu sup 3 sup + ion. The CF splittings of the sup 7 F sub 1 and sup 5 D sub 1 levels were also determined experimentally for the Eu sup 3 sup + ion...

  2. A Comparative Study on the Two English Versions of Lu Xun’s Stories

    Institute of Scientific and Technical Information of China (English)

    ZHOU Shi-pei

    2015-01-01

    The two English versions of Lu Xun’s stories, translated by Julia Lovell and the Rangs, are to be studied from the eco-translatological perspective. A comparative study of the two English versions is made to figure out how the two translators linguis⁃tically and culturally make adaptive selections in the process of translation of Lu Xun ’s stories—In other words, how the eco-en⁃vironment has greatly influenced the two translators’decisions to make adaptations and choices in linguistic and cultural aspects. The thesis discovers that the eco-environment has greatly influenced the process of translating Lu Xun ’s stories into English and eco-translatology is feasible to analyze the two translations, that both the Yangs and Lovell have offered successful translations by making adaptive selections and selective transformations. Therefore, neither of the two translations is superior or inferior to one another in different translational eco-environments. Hopefully, the thesis may enrich current researches on the Yang ’s and Lovell’s translations and may be useful for the further study of applying eco-translatology to studies on other translators and their works.

  3. Wobbling phonon excitations, coexisting with normal deformed structures in sup 1 sup 6 sup 3 Lu

    CERN Document Server

    Jensen, D R; Hamamoto, I; Oedegard, S W; Bergström, M H; Herskind, B; Sletten, G; Toermaenen, S; Wilson, J N; Tjøm, P O; Spohr, K; Hübel, H; Görgen, A; Schoenwasser, G; Bracco, A; Leoni, S; Maj, A; Petrache, C M; Bednarczyk, P; Curien, D

    2002-01-01

    Wobbling is a rotational mode unique to a triaxial body. The Lu-Hf isotopes with N approx 94 at high spin provide a possible region of nuclei with pronounced triaxiality. We have investigated sup 1 sup 6 sup 3 Lu through the fusion-evaporation reaction sup 1 sup 3 sup 9 La( sup 2 sup 9 Si,5n) sup 1 sup 6 sup 3 Lu with a beam energy of 152 MeV. Three excited bands decaying into the known, presumably triaxial, superdeformed (TSD) band built on the i sub 1 sub 3 sub / sub 2 proton orbital are observed. The electromagnetic properties of the connecting transitions from the two strongest populated excited TSD bands have been investigated. New particle-rotor calculations in which one i sub 1 sub 3 sub / sub 2 quasiproton is coupled to the core of triaxial shape produce a variety of bands, whose properties can clearly be interpreted either as 'wobbling' or 'cranking' motion of the core. Evidence for the assignment of the excited TSD bands as one, and possibly even two wobbling phonon modes built on the yrast TSD band...

  4. Atomic and electronic structures of lutetium oxide Lu{sub 2}O{sub 3}

    Energy Technology Data Exchange (ETDEWEB)

    Kaichev, V. V., E-mail: vvk@catalysis.ru [Russian Academy of Sciences, Boreskov Institute of Catalysis, Siberian Branch (Russian Federation); Asanova, T. I.; Erenburg, S. B. [Russian Academy of Sciences, Institute of Inorganic Chemistry, Siberian Branch (Russian Federation); Perevalov, T. V., E-mail: timson@isp.nsc.ru [Russian Academy of Sciences, Institute of Semiconductor Physics, Siberian Branch (Russian Federation); Shvets, V. A.; Gritsenko, V. A. [Russian Academy of Sciences, Institute of Semiconductor Physics, Siberian Branch (Russian Federation)

    2013-02-15

    The chemical composition, electronic structure, structure, and physical properties a lutetium oxide Lu{sub 2}O{sub 3} film are studied by X-ray photoelectron spectroscopy, ellipsometry, and X-ray absorption spectroscopy. The short-range order in Lu{sub 2}O{sub 3} is found to correspond to its cubic modification. The binding energies of the 1s and 2p levels of oxygen and the 4d{sub 5/2} and 4f{sub 7/2} levels of lutetium are 529.2, 5.0 and 7.4, 195.9 eV, respectively. The energy gap determined from the electron energy loss spectrum of the film is 5.9 eV. The electron energy loss spectra have two peaks at 17.4 and 22.0 eV, which can be attributed to the excitation of bulk plasma oscillations. The dispersion of the refractive index is measured by spectral ellipsometry. The refractive index is shown to increase from 1.82 at 1.5 eV to 2.18 at 5.0 eV, and the high-frequency permittivity of Lu{sub 2}O{sub 3} is 3.31.

  5. Illustrations of neurosurgical techniques in early period of Ottoman Empire by Serefeddin Sabuncuoğlu.

    Science.gov (United States)

    Turgut, M

    2007-10-01

    Serefeddin Sabuncuoğlu (A.D. 1385-1468) was the author of the first illustrated surgery atlas Cerrahiyyetü'l Haniyye (Imperial Surgery), which was written in Turkish in 1465. The purpose of this report is to present his unique contribution to modern neurological surgery. Cerrahiyyetü'l Haniyye consists of 412 pages in three chapters, in which there are a total of 191 sections dealing with a variety of surgical specialties, including neurosurgery. In each section of the book, a sentence written in rhyme and meter gives the diagnosis, classification and surgical technique in detail. Serefeddin Sabuncuoğlu describes medical and surgical management of neurological diseases such as spinal trauma, epilepsy, migraine, facial palsy, hemiplegia, low back pain, cranial fracture, hydrocephalus and abscesses of the head in his textbook. Serefeddin Sabuncuoğlu was a great surgeon in Turkish medical history and the sections on neurological diseases in Cerrahiyyetü'l Haniyye are of great importance in neurosurgery. Today, he is justified as a pioneer of surgery, an investigator and a medical illustrator in the early period of Ottoman Empire. His atlas is a modification of original contributions from earlier treatises.

  6. Geochronology of the volcanic rocks in the Lu-Zong basin and its significance

    Institute of Scientific and Technical Information of China (English)

    ZHOU TaoFa; FAN Yu; YUAN Feng; LU SanMing; SHANG ShiGui; David COOKE; Sebastien MEFFRE; ZHAO GuoChun

    2008-01-01

    The Lu-Zong (Lujiang-Zongyang) basin is one of the most important volcanic basins in the middle and lower reaches of the Yangtze River area, China. It comprises four shoshonitic volcanic units, which are,in an ascending order, the Longmenyuan, Zhuanqiao, Shuangmiao and Fushan Groups. The LA-ICP MS U-Pb zircon ages of the four units are: 134.8±1.8 Ma for the Longmenyuan Group, 134.1±1.6 Ma for the Zhuanqiao Group, 130.5±0.8 Ma for the Shuangmiao Group, and 127.1+1.2 Ma for the Fushan Group. The results indicate that all volcanic rocks in the Lu-Zong basin were formed in the Early Cretaceous from about 135 Ma to 127 Ma, lasting 8-10 Ma. There were no Jurassic volcanic activities in all the volcanic basins including the Lu-Zong basin in the middle and lower reaches of the Yangtze River area.This work has provided new chronological results for the further study and understanding of the tectonic, magmatic and metallogenic processes of eastern China in the Mesozoic.

  7. An ebCMOS camera system for marine bioluminescence observation: The LuSEApher prototype

    Energy Technology Data Exchange (ETDEWEB)

    Dominjon, A., E-mail: a.dominjon@ipnl.in2p3.fr [CNRS/IN2P3, Institut de Physique Nucleaire de Lyon, Villeurbanne F-69622 (France); Ageron, M. [CNRS/IN2P3, Centre de Physique des Particules de Marseille, Marseille, F-13288 (France); Barbier, R. [CNRS/IN2P3, Institut de Physique Nucleaire de Lyon, Villeurbanne F-69622 (France); Universite de Lyon, Universite Lyon 1, Lyon F-69003 (France); Billault, M.; Brunner, J. [CNRS/IN2P3, Centre de Physique des Particules de Marseille, Marseille, F-13288 (France); Cajgfinger, T. [CNRS/IN2P3, Institut de Physique Nucleaire de Lyon, Villeurbanne F-69622 (France); Universite de Lyon, Universite Lyon 1, Lyon F-69003 (France); Calabria, P. [CNRS/IN2P3, Institut de Physique Nucleaire de Lyon, Villeurbanne F-69622 (France); Chabanat, E. [CNRS/IN2P3, Institut de Physique Nucleaire de Lyon, Villeurbanne F-69622 (France); Universite de Lyon, Universite Lyon 1, Lyon F-69003 (France); Chaize, D.; Doan, Q.T.; Guerin, C.; Houles, J.; Vagneron, L. [CNRS/IN2P3, Institut de Physique Nucleaire de Lyon, Villeurbanne F-69622 (France)

    2012-12-11

    The ebCMOS camera, called LuSEApher, is a marine bioluminescence recorder device adapted to extreme low light level. This prototype is based on the skeleton of the LUSIPHER camera system originally developed for fluorescence imaging. It has been installed at 2500 m depth off the Mediterranean shore on the site of the ANTARES neutrino telescope. The LuSEApher camera is mounted on the Instrumented Interface Module connected to the ANTARES network for environmental science purposes (European Seas Observatory Network). The LuSEApher is a self-triggered photo detection system with photon counting ability. The presentation of the device is given and its performances such as the single photon reconstruction, noise performances and trigger strategy are presented. The first recorded movies of bioluminescence are analyzed. To our knowledge, those types of events have never been obtained with such a sensitivity and such a frame rate. We believe that this camera concept could open a new window on bioluminescence studies in the deep sea.

  8. Peculiarities of thermoelectric half-Heusler phase formation in Gd-Ni-Sb and Lu-Ni-Sb ternary systems

    Energy Technology Data Exchange (ETDEWEB)

    Romaka, V.V., E-mail: romakav@lp.edu.ua [Department of Applied Material Science and Materials Engineering, Lviv Polytechnic National University, Ustyyanovycha Str. 5, 79013 Lviv (Ukraine); Romaka, L.; Horyn, A. [Inorganic Chemistry Department, Ivan Franko Lviv National University, Kyryla and Mefodiya str. 6, 79005 Lviv (Ukraine); Rogl, P. [Institute of Materials Chemistry and Research, University of Vienna, Währingerstrasse 42, A-1090 Wien (Austria); Stadnyk, Yu; Melnychenko, N. [Inorganic Chemistry Department, Ivan Franko Lviv National University, Kyryla and Mefodiya str. 6, 79005 Lviv (Ukraine); Orlovskyy, M.; Krayovskyy, V. [Department of Applied Material Science and Materials Engineering, Lviv Polytechnic National University, Ustyyanovycha Str. 5, 79013 Lviv (Ukraine)

    2016-07-15

    The phase equilibria in the Gd–Ni–Sb and Lu-Ni-Sb ternary systems were studied at 873 K by X-ray and metallographic analyses in the whole concentration range. The interaction of the elements in the Gd–Ni–Sb system results the formation of five ternary compounds at investigated temperature: Gd{sub 5}Ni{sub 2}Sb (Mo{sub 5}SiB{sub 2}-type), Gd{sub 5}NiSb{sub 2} (Yb{sub 5}Sb{sub 3}-type), GdNiSb (MgAgAs-type), Gd{sub 3}Ni{sub 6}Sb{sub 5} (Y{sub 3}Ni{sub 6}Sb{sub 5}-type), and GdNi{sub 0.72}Sb{sub 2} (HfCuSi{sub 2}-type). At investigated temperature the Lu-Ni-Sb system is characterized by formation of the LuNiSb (MgAgAs-type), Lu{sub 5}Ni{sub 2}Sb (Mo{sub 5}SiB{sub 2}-type), and Lu{sub 5}Ni{sub 0.56}Sb{sub 2.44} (Yb{sub 5}Sb{sub 3}-type) compounds. The disordering in the crystal structure of half-Heusler GdNiSb and LuNiSb was revealed by EPMA and studied by means of Rietveld refinement and DFT modeling. The performed electronic structure calculations are in good agreement with electrical transport property studies. - Graphical abstract: Crystal structure model and electron localization function of Lu{sub 5}Ni{sub 2}Sb. Display Omitted - Highlights: • Gd-Ni-Sb and Lu-Ni-Sb phase diagrams were constructed at 873 K. • GdNiSb and LuNiSb are characterized by disordered crystal structure. • Crystal structure optimization with DFT calculations confirmed crystal structure disorder in GdNiSb and LuNiSb.

  9. Subacute haematotoxicity after PRRT with {sup 177}Lu-DOTA-octreotate: prognostic factors, incidence and course

    Energy Technology Data Exchange (ETDEWEB)

    Bergsma, Hendrik; Konijnenberg, Mark W.; Kam, Boen L.R.; Teunissen, Jaap J.M.; Kooij, Peter P.; Krenning, Eric P.; Kwekkeboom, Dik J. [Erasmus University Medical Center, Department of Nuclear Medicine, Rotterdam (Netherlands); Herder, Wouter W. de [Erasmus Medical Center, Department of Internal Medicine, Rotterdam (Netherlands); Franssen, Gaston J.H.; Eijck, Casper H.J. van [Erasmus Medical Center, Department of Surgery, Rotterdam (Netherlands)

    2016-03-15

    In peptide receptor radionuclide therapy (PRRT), the bone marrow (BM) is one of the dose-limiting organs. The accepted dose limit for BM is 2 Gy, adopted from {sup 131}I treatment. We investigated the incidence and duration of haematological toxicity and its risk factors in patients treated with PRRT with {sup 177}Lu-DOTA{sup 0}-Tyr{sup 3}-octreotate ({sup 177}Lu-DOTATATE). Also, absorbed BM dose estimates were evaluated and compared with the accepted 2 Gy dose limit. The incidence and duration of grade 3 or 4 haematological toxicity (according to CTCAE v3.0) and risk factors were analysed. Mean BM dose per unit (gigabecquerels) of administered radioactivity was calculated and the correlations between doses to the BM and haematological risk factors were determined. Haematological toxicity (grade 3/4) occurred in 34 (11 %) of 320 patients. In 15 of the 34 patients, this lasted more than 6 months or blood transfusions were required. Risk factors significantly associated with haematological toxicity were: poor renal function, white blood cell (WBC) count <4.0 x 10{sup 9}/l, age over 70 years, extensive tumour mass and high tumour uptake on the OctreoScan. Previous chemotherapy was not associated. The mean BM dose per administered activity in 23 evaluable patients was 67 ± 7 mGy/GBq, resulting in a mean BM dose of 2 Gy in patients who received four cycles of 7.4 GBq {sup 177}Lu-DOTATATE. Significant correlations between (cumulative) BM dose and platelet and WBC counts were found in a selected group of patients. The incidence of subacute haematological toxicity after PRRT with {sup 177}Lu-DOTATATE is acceptable (11 %). Patients with impaired renal function, low WBC count, extensive tumour mass, high tumour uptake on the OctreoScan and/or advanced age are more likely to develop grade 3/4 haematological toxicity. The BM dose limit of 2 Gy, adopted from {sup 131}I, seems not to be valid for PRRT with {sup 177}Lu-DOTATATE. (orig.)

  10. {sup 177}Lu-DOTMP: a viable agent for palliative radiotherapy of painful bone metastasis

    Energy Technology Data Exchange (ETDEWEB)

    Das, T.; Chakraborty, S.; Banerjee, S. [Radiopharmaceuticals Div., Bhabha Atomic Research Centre, Mumbai (India); Sarma, H.D. [Radiation Biology and Health Sciences Div., Bhabha Atomic Research Centre, Mumbai (India)

    2008-07-01

    The suitable nuclear decay characteristics [T{sub 1/2} = 6.73 d, E{sub {beta}}{sub (max)} = 497 keV, E{sub {gamma}} = 113 keV (6.4%), 208 keV (11%)] as well as the feasibility of large-scale production with adequate specific activity and radionuclidic purity using a moderate flux reactor are important attributes towards {sup 177}Lu to be considered as a promising radionuclide for palliative care in painful bone metastasis. The present study describes the preparation of {sup 177}Lu complex of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetramethylene phosphonic acid (DOTMP) and its preliminary biological evaluation in animal models with an aim to proposing it as a viable radiopharmaceutical for bone pain palliation. The choice DOTMP as the polyaminophosphonic acid carrier ligand is based on the enhanced thermodynamic stability and kinetic inertness of the metal-ligand complexes with macrocyclic chelators. {sup 177}Lu was produced with a specific activity of {proportional_to} 12 GBq/mg ({proportional_to} 324 mCi/mg) and radionuclidic purity of 99.98% by irradiation of natural Lu{sub 2}O{sub 3} target at a thermal neutron flux of {proportional_to} 6 x 10{sup 13} n/cm{sup 2} s for 21 d. {sup 177}Lu-DOTMP complex was prepared in high yield and excellent radiochemical purity (> 99%) using DOTMP synthesized and characterized in-house. The complex exhibited excellent in-vitro stability at room temperature. Biodistribution studies in Wistar rats showed rapid skeletal accumulation of the injected activity [(1.60{+-}0.19)% per gram in femur at 3 h post-injection] with fast clearance from blood and minimal uptake in any of the major organs. Scintigraphic studies carried out in normal Wistar rats and New Zealand white rabbits also demonstrated significant accumulation of the agent in skeleton and almost no retention in any other vital organs. (orig.)

  11. Gamma camera calibration and validation for quantitative SPECT imaging with (177)Lu.

    Science.gov (United States)

    D'Arienzo, M; Cazzato, M; Cozzella, M L; Cox, M; D'Andrea, M; Fazio, A; Fenwick, A; Iaccarino, G; Johansson, L; Strigari, L; Ungania, S; De Felice, P

    2016-06-01

    Over the last years (177)Lu has received considerable attention from the clinical nuclear medicine community thanks to its wide range of applications in molecular radiotherapy, especially in peptide-receptor radionuclide therapy (PRRT). In addition to short-range beta particles, (177)Lu emits low energy gamma radiation of 113keV and 208keV that allows gamma camera quantitative imaging. Despite quantitative cancer imaging in molecular radiotherapy having been proven to be a key instrument for the assessment of therapeutic response, at present no general clinically accepted quantitative imaging protocol exists and absolute quantification studies are usually based on individual initiatives. The aim of this work was to develop and evaluate an approach to gamma camera calibration for absolute quantification in tomographic imaging with (177)Lu. We assessed the gamma camera calibration factors for a Philips IRIX and Philips AXIS gamma camera system using various reference geometries, both in air and in water. Images were corrected for the major effects that contribute to image degradation, i.e. attenuation, scatter and dead- time. We validated our method in non-reference geometry using an anthropomorphic torso phantom provided with the liver cavity uniformly filled with (177)LuCl3. Our results showed that calibration factors depend on the particular reference condition. In general, acquisitions performed with the IRIX gamma camera provided good results at 208keV, with agreement within 5% for all geometries. The use of a Jaszczak 16mL hollow sphere in water provided calibration factors capable of recovering the activity in anthropomorphic geometry within 1% for the 208keV peak, for both gamma cameras. The point source provided the poorest results, most likely because scatter and attenuation correction are not incorporated in the calibration factor. However, for both gamma cameras all geometries provided calibration factors capable of recovering the activity in

  12. Promise and Pitfalls of Lu/Hf-Sm/Nd Garnet Geochronology

    Science.gov (United States)

    King, R. L.; Vervoort, J. D.; Kohn, M. J.; Zirakparvar, N. A.; Hart, G. L.; Corrie, S. L.; Cheng, H.

    2007-12-01

    Our ability to routinely measure Lu-Hf and Sm-Nd isotopes in garnet allows broad new applications in geochronology, petrology, and tectonics. However, applications of these data can be limited by challenges in interpreting the petrologic record and preparing garnets for analysis. Here, we examine petrologic and chemical pitfalls encountered in garnet geochronology. Petrologic factors influencing trace element compositions in garnet include reactions that modify REE availability and partitioning (1,2), kinetically limited transfer of REEs to garnet (3), and bulk compositional heterogeneities (4). Interpreting the effects of these processes on Sm/Nd and Lu/Hf ages requires characterizing REE zonation prior to isotope analysis and age interpretation. Because garnet fractions are traditionally picked from crushed samples without regard to intracrystalline origins or chemistries, isochrons will represent mixtures derived to varying degrees from all periods of garnet growth. While measured zoning might generally indicate what garnet portion dominates the Lu/Hf or Sm/Nd budget, traditional mineral separation will rarely realize the chronologic potential afforded by high precision Hf and Nd isotope measurements. The potential use of alternative techniques, such as microsampling, necessitates selective digestion and/or leaching to eliminate inclusions within garnet. For Sm/Nd geochronology, H2SO4 leaching removes LREE-rich phosphates (e.g. apatite), but not silicates (e.g. epidote), precluding Sm-Nd dating of some rocks. For Lu/Hf geochronology, ubiquitous zircon microinclusions (c. 1 μm) can significantly disrupt age determinations. Microinclusions cannot be detected optically or separated physically, requiring selective chemical digestion. If complete digestion methods, such as bomb digestion, are used for garnet fractions, then "common Hf" from zircon will be contained in final solutions. These mixed analyses are of dubious utility and will fall into one of two

  13. Afnám einkasölu áfengis. Yfirlit yfir rannsóknir á breytingum á áfengissölu

    Directory of Open Access Journals (Sweden)

    Hildigunnur Ólafsdóttir

    2007-12-01

    Full Text Available Í skýrslunni er gerð grein fyrir helstu rannsóknum sem gerðar hafa verið á breytingum á áfengiseinkasölu og aðgengi áfengis. Rannsóknir á breyttu fyrirkomulagi áfengissölu eru flestar frá Norður-Ameríku og Norðurlöndunum. Nær allar rannsóknirnar sýna að í kjölfar einkavæðingar á áfengissölu hefur áfengisneysla aukist. Ennfremur er greint frá rannsóknum á breytingum á áfengissköttum, sem leiða í ljós að lækkun þeirra eykur áfengisneyslu og tjón af völdum áfengis. Stuttlega er fjallað um rannsóknir á áfengiskaupaaldri, á reglum um áfengisauglýsingar og viðvörunarmerkingar á áfengi. Til þess að setja þessa þætti áfengisstefnunnar í víðara samhengi er gerð grein fyrir norrænu samstarfi um áfengismál á alþjóðlegum vettvangi og stöðu áfengismála hjá Alþjóðaheilbrigðismálastofnuninni og Evrópusambandinu. Greint er frá því að innan Alþjóðaheilbrigðismálastofnunarinnar er stefnt að samþykkt um áfengismál, sem verði baráttutæki gegn áfengisvandamálum. Þá er sagt frá stefnuskjali Evrópusambandsins og stofnun The European Alcohol and Health Forum, sem innan tíðar mun leggja fram aðgerðaáætlun til þess að vernda íbúa Evrópu gegn skaðlegri neyslu áfengis.

  14. 高明行旅昆山无锡事迹考%Gao Ming’s Travels to Kunshan and Wuxi (Research Report)

    Institute of Scientific and Technical Information of China (English)

    吴新雷

    2015-01-01

    Gao Ming(高明), Author of The Lute, had close and amicable ties with Gu Ying, and contact with figures in the Yushan salon. He participated in literati social events and had a wide circle of acquaintance. The poems and prose pieces that he wrote during his travels in Kunshan and Wuxi reflect Gao Ming’s state of mind on the road of life. On the one hand,he loathed the official life, and longed for seclusion. On the other hand, he advocated the philosophy of Confucius and Mencius, faithfully abiding by Confucianist philosophy. His moral structure is formed by the advocacy for loyalty, filial piety, righteousness, according to the traditional ethical concepts. This philosophical basis and concepts of value are what caused him to re-write the unfilial, disloyal scriptsSecond Son Cai as the loyal, filial scriptThe Lute.%作者高明与昆山的顾瑛颇有交谊,跟玉山雅集中人时有往来,曾参与顾瑛文士集团的社会活动,接触面甚广。其昆山无锡之行所作的诗文,则反映了高明在人生道路上的思想状态。一方面,他厌倦仕宦生涯,向往隐逸;另一方面,他又崇尚孔孟之道,忠实地恪守儒家精神。他的道德建构是竭力宣扬忠、孝、节、义,这是封建社会传统的伦理观念。这种思想基础和价值理念,造成了他把不忠不孝的《蔡二郎》写成了全忠全孝的《琵琶记》。

  15. Study on the Mechanism of Starch Retrogradation of MiGao%米制松糕回生机理的研究

    Institute of Scientific and Technical Information of China (English)

    纪莹; 周恵明

    2012-01-01

    The object of the research is to characterize changes in starch of MiGao during storage.The most significant change in the pasting curve is the increase in peak viscosity over time measured with a Rapid Visco Analyser.FT-IR indicates a reduced amount of amorphous material,giving a more organised starch because retrogradation commenced.Differential scanning calorimetry is used to follow changes of starch retrogradation in MiGao crumb,as we expected,retrogradation enthalpy increased with the storage time.All the results show that the main mechanism underlying the changes in properties is suggested be slow amylopectin crystallization.%通过对米制松糕贮存过程的热特性和结晶特性的研究,探讨松糕的回生机理。从样品的粘度特性分析可知,松糕的峰值粘度、低谷粘度、崩解值、最终粘度和回复值随贮存时间的延长逐渐增大,峰值时间随贮存时间的延长而逐渐减少,糊化温度降低;松糕淀粉主要的红外光谱说明淀粉颗粒中无定形分子迅速减少,有序分子逐渐增多,即淀粉的结晶度增加。通过热力学性质的分析表明,早期的重结晶融化顶点温度略高于后期的重结晶融化顶点温度,随着储藏时间的延长,融化支链淀粉重结晶所需的热焓增加,表明淀粉回生程度增加。

  16. 高才达主任医师白芍木瓜汤临床运用经验%Clinical Experiences about Medication of Baishao Mugua Decoction of Chief Physician Gao Caida

    Institute of Scientific and Technical Information of China (English)

    邱新红; 李淳; 邱新萍; 高才达

    2015-01-01

    白芍木瓜汤具有培补肝肾,舒筋通络止痛的功效.高才达主任医师灵活运用白芍木瓜汤加减治疗多种疾病.本文总结高师白芍木瓜汤的临床运用经验及典型医案数则.%Baishao Mugua Decoction can not only nourish liver and kidney but also relieve rigidity of muscles and activate collaterals. Chief Physician Gao uses Baishao Mugua Decoction flexibly to treat many diseases. The paper presented the experiences of Chief physician Gao who medicated modified Baishao Mugua Decoction and listed several clinical cases .

  17. Synthesis of oligosaccharides derived from lactulose (OsLu using soluble and immobilized Aspergillus oryzae b-galactosidase

    Directory of Open Access Journals (Sweden)

    ALEJANDRA eCARDELLE COBAS

    2016-03-01

    Full Text Available b-galactosidase from Aspergillus oryzae offers a high yield for the synthesis of oligosaccharides derived from lactulose (OsLu by transgalactosylation. Oligosaccharides with degree of polymerization (DP ≥ 3 have shown to possess higher in vitro bifidogenic effect than di- and tetrasaccharides. Thus, in this work, an optimization of reaction conditions affecting the specific selectivity of A. oryzae b-galactosidase for synthesis of OsLu has been carried out to enhance OsLu with DP ≥ 3 production. Assays with b-galactosidase immobilized onto a glutaraldehyde-agarose support were also carried out with the aim of making the process cost-effective and industrially viable. Optimal conditions with both soluble and immobilized enzyme for the synthesis of OsLu with DP ≥ 3 were 50 °C, pH 6.5, 450 g/L of lactulose and 8 U/mL of enzyme, reaching yields of ca. 50% (w/v of total OsLu and ca. 20% (w/v of OsLu-3, being 6′-galactosyl-lactulose the major one, after a short reaction time. Selective formation of disaccharides, however, was favored at 60 °C, pH 4.5, 450 g/L of lactulose and 8 U/mL of enzyme. Immobilization increased the enzymatic stability to temperature changes and allowed to reuse the enzyme. We can conclude that the use, under determined optimal conditions, of the A. oryzae b-galactosidase immobilized on a support of glutaraldehyde-agarose constitutes an efficient and cost-effective alternative to the use of soluble b-galactosidases for the synthesis of prebiotic OsLu mixtures.

  18. 177Lu-DOTA-HH1, a Novel Anti-CD37 Radio-Immunoconjugate: A Study of Toxicity in Nude Mice

    Science.gov (United States)

    Repetto-Llamazares, Ada H. V.; Larsen, Roy H.; Giusti, Anna Maria; Riccardi, Elena; Bruland, Øyvind S.; Selbo, Pål Kristian; Dahle, Jostein

    2014-01-01

    Background CD37 is an internalizing B-cell antigen expressed on Non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia cells (CLL). The anti-CD37 monoclonal antibody HH1 was conjugated to the bifunctional chelator p-SCN-Bn-DOTA and labelled with the beta-particle emitting radionuclide 177Lu creating the radio-immunoconjugate (RIC) 177Lu-DOTA-HH1 (177Lu-HH1, trade name Betalutin). The present toxicity study was performed prior to initiation of clinical studieswith 177Lu-HH1. Methodology/Principal Findings Nude mice with or without tumor xenografts were treated with 50 to 1000 MBq/kg 177Lu- HH1 and followed for clinical signs of toxicity up to ten months. Acute, life threatening bone marrow toxicity was observed in animals receiving 800 and 1000 MBq/kg 177Lu-HH1. Significant changes in serum concentrations of liver enzymes were evident for treatment with 1000 MBq/kg 177Lu-HH1. Lymphoid depletion, liver necrosis and atrophy, and interstitial cell hyperplasia of the ovaries were also observed for mice in this dose group. Conclusions/Significance 177Lu-DOTA-HH1 was well tolerated at dosages about 10 times above those considered relevant for radioimmunotherapy in patients with B-cell derived malignancies.The toxicity profile was as expected for RICs. Our experimental results have paved the way for clinical evaluation of 177Lu-HH1 in NHL patients. PMID:25068508

  19. 177Lu-DOTA-HH1, a novel anti-CD37 radio-immunoconjugate: a study of toxicity in nude mice.

    Directory of Open Access Journals (Sweden)

    Ada H V Repetto-Llamazares

    Full Text Available CD37 is an internalizing B-cell antigen expressed on Non-Hodgkin lymphoma (NHL and chronic lymphocytic leukemia cells (CLL. The anti-CD37 monoclonal antibody HH1 was conjugated to the bifunctional chelator p-SCN-Bn-DOTA and labelled with the beta-particle emitting radionuclide 177Lu creating the radio-immunoconjugate (RIC 177Lu-DOTA-HH1 (177Lu-HH1, trade name Betalutin. The present toxicity study was performed prior to initiation of clinical studies with 177Lu-HH1.Nude mice with or without tumor xenografts were treated with 50 to 1000 MBq/kg 177Lu- HH1 and followed for clinical signs of toxicity up to ten months. Acute, life threatening bone marrow toxicity was observed in animals receiving 800 and 1000 MBq/kg 177Lu-HH1. Significant changes in serum concentrations of liver enzymes were evident for treatment with 1000 MBq/kg 177Lu-HH1. Lymphoid depletion, liver necrosis and atrophy, and interstitial cell hyperplasia of the ovaries were also observed for mice in this dose group.177Lu-DOTA-HH1 was well tolerated at dosages about 10 times above those considered relevant for radioimmunotherapy in patients with B-cell derived malignancies.The toxicity profile was as expected for RICs. Our experimental results have paved the way for clinical evaluation of 177Lu-HH1 in NHL patients.

  20. "肤敏"膏抑制小鼠变应性接触性皮炎机制的研究%Experimental Study on "Fu Min" Gao Inhibiting Allergic Contact Dermatitis in Murine Model

    Institute of Scientific and Technical Information of China (English)

    李静平; 李庆生; 李杰

    2011-01-01

    目的:研究"肤敏"膏滋剂对小鼠变应性接触性皮炎(ACD)的抑制作用,探讨其作用机理.方法:以DNFB和FITC分别建立小鼠ACD模型.采用ELISA法检测ACD小鼠产生干扰素-γ (IFN-γ)、肿瘤坏死因子-α(TNF-α)、白介素4和6(IL-4、IL-6)的水平及"肤敏"膏对4种细胞因子的作用.结果:口服不同剂量"肤敏"膏对4种细胞因子均有显著或不同程度的抑制作用(P<0.05或P<0.01).结论:"肤敏"膏对小鼠ACD疗效可能通过抑制Th1/Th2细胞因子而发挥作用.%Objective: To investigate the mechanism of "Fu Min" Gao inhibiting allergic contact dermatitis (ACD) in murine model. Methods:The murine model of allergic contact dermatitis by topical DNCB and FITC were used. After oral administration of "Fu Min" Gao in different doses, The levels of IFN - γ,TNF - α, IL - 4 and IL - 6 in the serum of these mice were detected by enzyme- linked immunosorbent assay (ELISA). Result: Different doses of "Fu Min" Gao inhibited the expression of these four cytokines to different degrees. ( P <0.05 or P < 0.01 ). Conclusion: The therapeutic effect of "Fu Min" Gao on murine ACD may be played by inhibiting the expression of some cytokines of helper T lymphocyte.

  1. The crystal structure and thermal expansion of the perovskite-type Nd0.75Sm0.25GaO3: powder diffraction and lattice dynamical studies

    Science.gov (United States)

    Senyshyn, A.; Oganov, A. R.; Vasylechko, L.; Ehrenberg, H.; Bismayer, U.; Berkowski, M.; Matkovskii, A.

    2004-01-01

    The structure of Nd0.75Sm0.25GaO3 was studied by high-resolution powder diffraction methods using conventional x-ray and synchrotron radiation in the temperature range 85-1173 K. The GdFeO3 structure type was confirmed for Nd0.75Sm0.25GaO3 in the temperature region investigated and no structural transitions were observed. The cell parameters show a monotonic and anisotropic increase with temperature. The interatomic potential was fitted using the GULP code. Using this potential, a self-consistent approximation following the Debye model was constructed from the elastic constants of the crystals. The total phonon DOS, its projections onto atomic species, heat capacity Cv, Grüneisen parameter ggr and thermal expansion coefficient agr were considered in the framework of quasiharmonic lattice dynamics and the Debye model. The shape of the phonon DOS calculated from lattice dynamics differs significantly from the respected Debye DOS. The rare earth, gallium and oxygen atoms dominate in different frequency regions of the phonon spectrum. The heat capacity is well reproduced by the Debye model below 100 K, where acoustic phonons play an important role and above 800 K when the classical limit is reached. Predicted values of Grüneisen parameter and thermal expansion coefficients in the frame of the Debye model are {\\sim } 35% too low. Therefore, the thermal properties of Nd0.75Sm0.25GaO3 cannot be explained by acoustic phonons only and hence, Nd0.75Sm0.25GaO3 cannot be described perfectly as a Debye-like solid with respect to its thermodynamic properties.

  2. WOMEN’S PROBLEMATIC AT NOVELS BY AFET (MUHTEREMOĞLU ILGAZ AFET (MUHTEREMOĞLU ILGAZ’IN ROMANLARINDA KADIN SORUNSALI

    Directory of Open Access Journals (Sweden)

    Zehra YAZBAHAR

    2011-06-01

    Full Text Available From Tanzimat to Rebuclic, women were examined in various aspects by very important part of Turkish novelists. Women's place in society by men and women in second place among the questions the writers of Afet (Muhteremoğlu Ilgaz also mention the name.In this study, classified in terms of subject Afet Ilgaz’s novels after a brief introduction and overview of feminist discourse with the struggle for independence, the author traces of her novels had been discussed Tanzimat’tan Cumhuriyet dönemine kadar kadın konusu, çeşitli yönleriyle, Türk romancılarının önemli bir kısmı tarafından ele anılıp, incelenmiştir. Kadının toplum içindeki yerini ve kadının erkeğe göre ikinciliğini sorgulayan yazarlar arasında Afet (Muhteremoğlu Ilgaz’ın da ismi sayılabilir. Bu çalışmada, Afet Ilgaz’ın romanlarını konu bakımından sınıflandıran kısa bir girişten sonra yazarın romanlarında kadına bakış ve feminist söylemin izleri ile bağımsızlık ve varoluş mücadelesi ele alınmaya çalışıldı.

  3. 高碳帘线钢精炼渣组成研究%Reserch on Gao Tanlian Line Steel Refining Slag

    Institute of Scientific and Technical Information of China (English)

    任文卓

    2014-01-01

    随着社会经济的迅速发展,我国对钢铁的需求量也越来越大,帘线钢作为洁净钢中的代表受到了人们的青睐。帘线钢在生产应用中,其质量主要取决于帘线用钢坯的质量及帘线盘条的性能及质量,一旦其含有杂物或硫化物,则会直接影响帘线钢的生产质量,本文在此针对高碳帘线钢精炼渣的组成做如下论述。%with the rapid development of social economy , China's steel demand is also growing , tire cord steel as represent-ative of clean steel in favored by the people .Tire cord steel in the production application , mainly depends on its quality in line with the performance and quality of billet quality and connecting rod , once its containing debris or sulfide , it will di-rectly affect the tire cord steel production quality , composition in this to Gao Tanlian line steel refining slag are discussed .

  4. Examples of treatment by classical prescriptions from GAO She­guang%高社光运用经方治验举隅

    Institute of Scientific and Technical Information of China (English)

    康日新

    2014-01-01

    Classical prescriptions are highly respected for its outstanding curative effect. Although generation shift and talented doctors explained, the origin of the classical prescriptions cannot be ignored. Nowadays, classical prescriptions are still effective in clinical application, all the doctor masters treat it as the Bible. Professor GAO She­guang is a famous Traditional Chinese Medicine doctor,who has been engaged in clinical medicine and scientific research work for long time. He is good at treating the internal medicine miscellaneous diseases, and also good at various departments with excellent curative effects.%经方因其疗效卓著,备受医家推崇,历传不衰。虽年移代革,英才辈出,时有发挥,然总不能脱经方之渊源。时至今日,仍然有效地应用于临床,众名医高手无不奉为圭臬。高社光教授是著名中医临床家,一直从事中医临床、科研工作,长于内科疑难杂病,旁及诸科,临证善用经方,平中出奇,每收良效。

  5. Image Mosaicking Approach for a Double-Camera System in the GaoFen2 Optical Remote Sensing Satellite Based on the Big Virtual Camera.

    Science.gov (United States)

    Cheng, Yufeng; Jin, Shuying; Wang, Mi; Zhu, Ying; Dong, Zhipeng

    2017-06-20

    The linear array push broom imaging mode is widely used for high resolution optical satellites (HROS). Using double-cameras attached by a high-rigidity support along with push broom imaging is one method to enlarge the field of view while ensuring high resolution. High accuracy image mosaicking is the key factor of the geometrical quality of complete stitched satellite imagery. This paper proposes a high accuracy image mosaicking approach based on the big virtual camera (BVC) in the double-camera system on the GaoFen2 optical remote sensing satellite (GF2). A big virtual camera can be built according to the rigorous imaging model of a single camera; then, each single image strip obtained by each TDI-CCD detector can be re-projected to the virtual detector of the big virtual camera coordinate system using forward-projection and backward-projection to obtain the corresponding single virtual image. After an on-orbit calibration and relative orientation, the complete final virtual image can be obtained by stitching the single virtual images together based on their coordinate information on the big virtual detector image plane. The paper subtly uses the concept of the big virtual camera to obtain a stitched image and the corresponding high accuracy rational function model (RFM) for concurrent post processing. Experiments verified that the proposed method can achieve seamless mosaicking while maintaining the geometric accuracy.

  6. Lu Xun's Essays and Customs of Shaoxing%鲁迅杂文与绍兴习俗

    Institute of Scientific and Technical Information of China (English)

    赵献涛

    2012-01-01

    Lu Xun's essays and Shaoxing customs are closely linked. The life in such folk spirit touched, influenced Lu Xun and raised his characteristics. The personality flow in the art atmosphere and its of Lu Xun's essays, forming a different type of essay, a steady wildness. The wildness of Lu Xun's essays is the formation of Shaoxing customs which brought the result of Lu Xun's personality.%鲁迅杂文与绍兴生活民俗存在着密切联系。鲁迅自幼生活于其间的民间习俗氛围以及它所蕴涵的精神触动着、影响着鲁迅,并养育了他的个性。这种个性气质流淌在鲁迅杂文的艺术园地里,形成一种与众不同的杂文意蕴,即一种泼辣辣的野气。鲁迅杂文所张扬着的野气的形成是绍兴民间习俗所养育的鲁迅个性的必然结果。

  7. Fabrication, microstructure and luminescence properties of Cr3+ doped Lu3A15O12 red scintillator ceramics

    Science.gov (United States)

    Shi, Yun; Zhao, Yu; Liu, Qiang; Cao, Maoqing; Ma, Peng; Chen, Haohong; Liu, Qian; Li, Jiang

    2017-04-01

    Cr3+ doped Lu3A15O12 transparent ceramics were developed as a new red scintillator ceramics. These ceramics were fabricated by a solid state reaction method under vacuum sintering at temperature range of 1550 °C-1890 °C for 10 h. The doping effect of different Cr3+ concentration (0, 0.1, 0.3 and 0.5 at. %) and air annealing effect were investigated as well. The transparent ceramics (70% @1 mm in visible light range) with dense microstructure were obtained when sintered at 1890 °C for 10 h, the average grain size of 0.3 at.% Cr:LuAG was calculated to be 7 μm. Photo-luminescence spectra revealed that there are two typical excitation bands at around 450 nm and 600 nm which were ascribed to the d-d transitions of Cr3+. 0.3 at. % Cr:LuAG exhibited the optimum photoluminescence intensity and fast decay. Radio-luminescence under X-ray excitation indicated a characteristic Cr3+ emission peaking at 687 nm and 706 nm respectively. The Lu3+Al antisite defects related emission at around 300 nm was observed to decrease with the doping of Cr3+. The steady luminescence efficiency (XEL spectrum integral) is around 20 times of the commercial BGO crystals, more important, the broad and continuous red emission between 600 nm and 800 nm demonstrated Cr:LuAG ceramics a prospective application as new red scintillators.

  8. 鲁迅民俗观形成的历史考察%Historical Study of Lu Xun's Folklore Viewpoints

    Institute of Scientific and Technical Information of China (English)

    赵献涛

    2012-01-01

    鲁迅民俗观的形成,主要与国外人类学派民俗观、中国现代民俗学运动的影响有关。与借民俗以研究历史或表达人生情趣不同,鲁迅的民俗观是一种启蒙致用的民俗观,但其部分观念并没有超出同时代的其他人物。人类学派民俗观与中国现代民俗学运动,成就了鲁迅的民俗视野,但同时也弱化了鲁迅的思想。%Formation of Lu Xun's folklore viewpoints closely associated with the foreign anthropology folklore viewpoints and modern folklore movement of China.Being different from studying the history and expressing life interest through the folklore,Lu Xun's folklore viewpoints was a kind of practical enlightenment.But some ideas of Lu Xun's folklore viewpoints do not go beyond other contemporary folklorists.Lu Xun's folklore viewpoints were formed by the foreign anthropology folklore viewpoints and the modern folklore movement of China,and to some extent Lu Xun's thoughts were weakened by them too.

  9. The locus for apolipoprotein E (apoE) is close to the Lutheran (Lu) blood group locus on chromosome 19.

    Science.gov (United States)

    Gedde-Dahl, T; Olaisen, B; Teisberg, P; Wilhelmy, M C; Mevåg, B; Helland, R

    1984-01-01

    Linkage has been described between the loci for apolipoprotein E (apoE) and the complement C3 (C3) on chromosome 19. C3 is known to belong to a linkage group with gene order C3-Se-Lu. The present study revealed linkage between Se and apoE with peak lod score +3.3 at recombination fraction 0.08 in males and +1.36 at 0.22 in females, and linkage between apoE and Lu with lod score +4.52 at zero recombination in sexes combined. The C3-apoE linkage gives lod score +4.00 at theta = 0.18 in males, but +0.04 at theta = 0.45 in females. Triple heterozygote families confirm that apoE is on the Se side and on the Lu side of C3. Allelic association between apoE and Lu has not been ruled out. Combining our data with published data on C3-Se and Se-Lu, this segment of chromosome 19 has an average age sex ratio of female/male recombination of 2.3.

  10. Crystal growth and optical properties of Gd admixed Ce-doepd Lu2Si2O7 single crystals

    Science.gov (United States)

    Horiai, Takahiko; Kurosawa, Shunsuke; Murakami, Rikito; Yamaji, Akihiro; Shoji, Yasuhiro; Ohashi, Yuji; Pejchal, Jan; Kamada, Kei; Yokota, Yuui; Yoshikawa, Akira

    2017-06-01

    Ce-doped Lu2Si2O7 scintillator contains radioactive isotope 176Lu which causes an unwanted intrinsic background signal. The development of scintillators with reduced Lu concentration were required in some applications. In this study, we developed the Gd admixed lutetium pyrosilicate, where the average ion radius at the rare earth site was similar to the Tm3+ ion radius, for which the RE2Si2O7 (RE=Tm, Yb, Lu) crystal structure is stable from room temperature to melting point. We have grown (Cex Lu1-x-y Gdy)2Si2O7 (x=0.01, y=0.00, 0.05, 0.10) single crystals. Their crystal systems were monoclinic with a space group C2/m. The absorption spectra revealed the energy transitions in Ce and Gd ions might be occurred. The light output was degraded and decay time was accelerated comparing the Gd 5% admixed sample with the Gd 10% one.

  11. On the structural origin of the single-ion magnetic anisotropy in LuFeO 3

    Energy Technology Data Exchange (ETDEWEB)

    Cao, Shi; Zhang, Xiaozhe; Paudel, Tula R.; Sinha, Kishan; Wang, Xiao; Jiang, Xuanyuan; Wang, Wenbin; Brutsche, Stuart; Wang, Jian; Ryan, Philip J.; Kim, Jong-Woo; Cheng, Xuemei; Tsymbal, Evgeny Y.; Dowben, Peter A.; Xu, Xiaoshan

    2016-03-16

    The electronic structure for the conduction bands of both hexagonal and orthorhombic LuFeO3 thin films have been measured using x-ray absorption spectroscopy at oxygen K (O K) edge. Dramatic differences in both the spectral features and the linear dichroism are observed. These differences in the spectra can be explained using the differences in crystal field splitting of the metal (Fe and Lu) electronic states and the differences in O 2p-Fe 3d and O 2p-Lu 5d hybridizations. While the oxidation states have not changed, the spectra are sensitive to the changes in the local environments of the Fe3+ and Lu3+ sites in the hexagonal and orthorhombic structures. Using the crystal-field splitting and the hybridizations that are extracted from the measured electronic structures and the structural distortion information, we derived the occupancies of the spin minority states in Fe3+, which are non-zero and uneven. The single ion anisotropy on Fe3+ sites is found to originate from these uneven occupancies of the spin minority states via spin–orbit coupling in LuFeO3.

  12. Time over threshold based multi-channel LuAG-APD PET detector

    Science.gov (United States)

    Shimazoe, Kenji; Orita, Tadashi; Nakamura, Yasuaki; Takahashi, Hiroyuki

    2013-12-01

    To achieve efficient signal processing, several time-based positron emission tomography (PET) systems using a large number of granulated gamma-ray detectors have recently been proposed. In this work described here, a 144-channel Pr:LuAG avalanche photodiode (APD) PET detector that uses time over threshold (ToT) and pulse train methods was designed and fabricated. The detector is composed of 12×12 Pr:LuAG crystals, each of which produces a 2 mm×2 mm×10 mm pixel individually coupled to a 12×12 APD array, which in turn is connected pixel-by-pixel with one channel of a time over threshold based application-specific integrated circuit (ToT-ASIC) that was designed and fabricated using a 0.25 μm 3.3 V Taiwan Semiconductor Company complementary metal oxide semiconductor (TSMC CMOS) process. The ToT outputs are connected through a field-programmable gate array (FPGA) to a data acquisition (DAQ) system. Three front-end ASIC boards-each incorporating a ToT-ASIC chip, threshold control digital-to-analog converters (DACs), and connectors, and dissipating power at about 230 mW per board-are used to read from the 144-channel LuAG-APD detector. All three boards are connected through an FPGA board that is programmed to calibrate the individual thresholds of the ToT circuits to allow digital multiplexing to form an integrated PET module with a measured timing resolution of 4.2 ns. Images transmitted by this PET system can be successfully acquired through collimation masks. As a further implementation of this technology, an animal PET system consisting of eight gamma pixel modules forming a ring is planned.

  13. Time over threshold based multi-channel LuAG-APD PET detector

    Energy Technology Data Exchange (ETDEWEB)

    Shimazoe, Kenji, E-mail: shimazoe@it-club.jp [Department of Nuclear Engineering and Management, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan); Orita, Tadashi [Department of Nuclear Engineering and Management, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan); Nakamura, Yasuaki [Department of Bioengineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan); Takahashi, Hiroyuki [Department of Nuclear Engineering and Management, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan); Department of Bioengineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan)

    2013-12-11

    To achieve efficient signal processing, several time-based positron emission tomography (PET) systems using a large number of granulated gamma-ray detectors have recently been proposed. In this work described here, a 144-channel Pr:LuAG avalanche photodiode (APD) PET detector that uses time over threshold (ToT) and pulse train methods was designed and fabricated. The detector is composed of 12×12 Pr:LuAG crystals, each of which produces a 2 mm×2 mm×10 mm pixel individually coupled to a 12×12 APD array, which in turn is connected pixel-by-pixel with one channel of a time over threshold based application-specific integrated circuit (ToT-ASIC) that was designed and fabricated using a 0.25 μm 3.3 V Taiwan Semiconductor Company complementary metal oxide semiconductor (TSMC CMOS) process. The ToT outputs are connected through a field-programmable gate array (FPGA) to a data acquisition (DAQ) system. Three front-end ASIC boards—each incorporating a ToT-ASIC chip, threshold control digital-to-analog converters (DACs), and connectors, and dissipating power at about 230 mW per board—are used to read from the 144-channel LuAG-APD detector. All three boards are connected through an FPGA board that is programmed to calibrate the individual thresholds of the ToT circuits to allow digital multiplexing to form an integrated PET module with a measured timing resolution of 4.2 ns. Images transmitted by this PET system can be successfully acquired through collimation masks. As a further implementation of this technology, an animal PET system consisting of eight gamma pixel modules forming a ring is planned.

  14. 卢作孚的伦理管理%Ethical Management of Lu Zuofu

    Institute of Scientific and Technical Information of China (English)

    王威

    2014-01-01

    Lu Zuofu implemented ethical management in Minsheng Corporation, took the realization of the overall modernization of China as the ethical objective of his company by making ethical decision for his company from the angle of serving the society and meanwhile by emphasizing the cultivation of the morality of his employees. Lu Zuofu, as the company manager, made himself an example and sticked to ethical leadship, which played a model role in the ethical selection of his employees. The ethical man-agement of Lu Zuofu made Minsheng Corporation have ethical advantage with unique characteristcs, which were further trans-formed into competitive advantage to forcefully ensure Minsheng Corporation to become the largest shipping group with Chinese private capital in modern China.%卢作孚在民生公司进行伦理管理,把帮助实现国家整体现代化作为公司的伦理目标,从服务社会的角度对公司进行伦理决策,同时重视员工的德性培育。卢作孚作为公司总经理以身垂范,坚持伦理领导,对员工的道德选择起到示范作用。卢作孚的伦理管理使民生公司形成独具特色的伦理优势,并进一步转化为竞争优势,有力地保证了公司发展成为近代中国最大的民族资本航运集团。

  15. DNA damage in blood lymphocytes in patients after {sup 177}Lu peptide receptor radionuclide therapy

    Energy Technology Data Exchange (ETDEWEB)

    Eberlein, Uta; Bluemel, Christina; Buck, Andreas Konrad; Werner, Rudolf Alexander; Lassmann, Michael [University of Wuerzburg, Department of Nuclear Medicine, Wuerzburg (Germany); Nowak, Carina; Scherthan, Harry [Bundeswehr Institute of Radiobiology affiliated to the University of Ulm, Munich (Germany)

    2015-10-15

    The aim of the study was to investigate DNA double strand break (DSB) formation and its correlation with the absorbed dose to the blood lymphocytes of patients undergoing their first peptide receptor radionuclide therapy (PRRT) with {sup 177}Lu-labelled DOTATATE/DOTATOC. The study group comprised 16 patients receiving their first PRRT. At least six peripheral blood samples were obtained before, and between 0.5 h and 48 h after radionuclide administration. From the time-activity curves of the blood and the whole body, residence times for blood self-irradiation and whole-body irradiation were determined. Peripheral blood lymphocytes were isolated, fixed with ethanol and subjected to immunofluorescence staining for colocalizing γ-H2AX/53BP1 DSB-marking foci. The average number of DSB foci per cell per patient sample was determined as a function of the absorbed dose to the blood and compared with an in vitro calibration curve established in our laboratory with {sup 131}I and {sup 177}Lu. The average number of radiation-induced foci (RIF) per cell increased over the first 5 h after radionuclide administration and decreased thereafter. A linear fit from 0 to 5 h as a function of the absorbed dose to the blood agreed with our in vitro calibration curve. At later time-points the number of RIF decreased, indicating progression of DNA repair. Measurements of RIF and the absorbed dose to the blood after systemic administration of {sup 177}Lu may be used to obtain data on the individual dose-response relationships in vivo. Individual patient data were characterized by a linear dose-dependent increase and an exponential decay function describing repair. (orig.)

  16. (90) Y/(177) Lu-labelled Cetuximab immunoconjugates: radiochemistry optimization to clinical dose formulation.

    Science.gov (United States)

    Chakravarty, Rubel; Chakraborty, Sudipta; Sarma, Haladhar Dev; Nair, K V Vimalnath; Rajeswari, Ardhi; Dash, Ashutosh

    2016-07-01

    Radiolabelled monoclonal antibodies (mAbs) are increasingly being utilized in cancer theranostics, which is a significant move toward tailored treatment for individual patients. Cetuximab is a recombinant, human-mouse chimeric IgG1 mAb that binds to the epidermal growth factor receptor with high affinity. We have optimized a protocol for formulation of clinically relevant doses (~2.22 GBq) of (90) Y-labelled Cetuximab and (177) Lu-labelled Cetuximab by conjugation of the mAb with a suitable bifunctional chelator, N-[(R)-2-amino-3-(paraisothiocyanato-phenyl)propyl]-trans-(S,S)-cyclohexane-1,2-diamine-N,N,N',N″,N″-pentaacetic acid (CHX-A″-DTPA). The radioimmunoconjugates demonstrated reasonably high specific activity (1.26 ± 0.27 GBq/mg for (90) Y-CHX-A″-DTPA-Cetuximab and 1.14 ± 0.15 GBq/mg for (177) Lu-CHX-A″-DTPA-Cetuximab), high radiochemical purity (>95%) and appreciable in vitro stability under physiological conditions. Preliminary biodistribution studies with both (90) Y-CHX-A″-DTPA-Cetuximab and (177) Lu-CHX-A″-DTPA-Cetuximab in Swiss mice bearing fibrosarcoma tumours demonstrated significant tumour uptake at 24-h post-injection (p.i.) (~16%ID/g) with good tumour-to-background contrast. The results of the biodistribution studies were further corroborated by ex vivo Cerenkov luminescence imaging after administration of (90) Y-CHX-A″-DTPA-Cetuximab in tumour-bearing mice. The tumour uptake at 24 h p.i. was significantly reduced with excess unlabelled Cetuximab, suggesting that the uptake was receptor mediated. The results of this study hold promise, and this strategy should be further explored for clinical translation.

  17. A study of response of a LuYAP:Ce array with innovative assembling for PET

    Energy Technology Data Exchange (ETDEWEB)

    Pani, Roberto [Department of Sciences and Medical and Surgical Biotechnology, Sapienza University of Rome, Rome (Italy); Cinti, Maria Nerina, E-mail: marianerina.cinti@uniroma1.it [Department of Molecular Medicine, Sapienza University of Rome, Rome (Italy); Scafè, Raffaele [Department of Molecular Medicine, Sapienza University of Rome, Rome (Italy); Bennati, Paolo [Department of Medical Engineering, Royal Institute of Technology (KTH), Stockholm (Sweden); Lo Meo, Sergio [ENEA, Ezio Clementel Research Center, Bologna (Italy); Preziosi, Enrico [Department of Molecular Medicine, Sapienza University of Rome, Rome (Italy); Morphofunctional Sciences – Biophysics, Doctorate School of Biology and Molecular Medicine – SAIMLAL Department, Sapienza University of Rome, Rome (Italy); Pellegrini, Rosanna [Department of Molecular Medicine, Sapienza University of Rome, Rome (Italy); De Vincentis, Giuseppe [Department of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza University of Rome, Rome (Italy); Sacco, Donatella [INAIL, DIPIA, Monteporzio, Rome (Italy); Fabbri, Andrea [Department of Molecular Medicine, Sapienza University of Rome, Rome (Italy)

    2015-09-21

    We propose the characterization of a first array of 10×10 Lutetium Yttrium Orthoaluminate Perovskite (LuYAP:Ce) crystals, 2 mm×2 mm×10 mm pixel size, with an innovative assembling designed to enhance light output, uniformity and detection efficiency. The innovation consists of the use of 0.015 mm thick dielectric coating as inter-pixel light-insulators, manufactured by Crytur (Czech Republic) intended to improve crystal insulation and then light collection. Respect to the traditional treatment with 0.2 mm of white epoxy, a thinner pixel gap enhances packing fraction up to 98% with a consequent improvement of detection efficiency. Spectroscopic characterization of the array was performed by a Hamamatsu R6231 photomultiplier tube. A pixel-by-pixel scanning with a collimated {sup 99m}Tc radioisotope (140 keV photon energy) highlighted a deviation in pulse height close to 3.5% respect to the overall mean value. Meanwhile, in term of energy resolution a difference between the response of single pixel and the array of about 10% was measured. Results were also supported and validated by Monte Carlo simulations performed with GEANT4. Although the dielectric coating pixel insulator cannot overcome the inherent limitations of LuYAP crystal due to its self-absorption of light (still present), this study demonstrated that the new coating treatment allows better light collection (nearly close to the expected one) with in addition a very good uniformity between different pixels. These results confirm the high potentiality of this coating for any other crystal array suited for imaging application and new expectations for the use of LuYAP for PET systems.

  18. Effects of long-term external use of Goupi Gao on renal functions and lead accumulation in rats%长期外用狗皮膏对大鼠肾功能及铅蓄积的影响

    Institute of Scientific and Technical Information of China (English)

    曾勇; 李帆帆; 李纯刚; 陈怀斌; 赵贵琴; 孟宪丽

    2012-01-01

    目的:观察长期外用狗皮膏对大鼠肾功能影响及铅在肾脏蓄积情况.方法:长期(90 d)外用给予7,3.5,1.75 g·kg-13个剂量狗皮膏,检测给药45,90d肾脏指数,血清尿素(BU),肌酐(Cr),尿β2-微球蛋白(β2-MG),N-乙酰-β-D-氨基葡萄糖苷酶(NAG)含量,并对肾脏做病理学检查;采用原子吸收光谱法测定肾脏铅的含量.结果:狗皮膏连续外用90d高、中剂量组大鼠肾脏指数增高,高剂量组尿NAG增高,给药组肾脏铅含量明显高于空白对照组,而BU,Cr,β2-MG,肾病理学无明显改变.结论:在本剂量范围内,狗皮膏连续高剂量外用90d可使大鼠肾脏指数增高、铅在肾脏蓄积、尿液NAG增高,但未影响到肾脏的排泄能力和发生器质性改变.%Objective: To observe the effect of long-term external use of Goupi Gao on renal function and lead accumulation in rats. Method: Rats were externally administered with Goupi Gao at different doses (7, 3.5 and 1. 75 g ? Kg-1) for 90 d. At 45 days and 90 days after administration, the renal indicator, levels of blood urea nitrogen ( BU) and creatinine (Cr) in serum, β2-microglobu-lin (β2-MG) and N-acetyl-β-D-glucosaminidase (NAG) in urine were determined. Lead content in kidneys was detected by atomic absorption spectrometry. Result: A 90-day administration with Goupi Gao significantly enhanced the renal indicator, levels of NAG in urine and lead content in renal, when compared with the normal rats. However, the levels of BUN and β2-MG as well as renal pathology in Goupi Gao treated rats were not obviously changed. Conclusion: Consecutive administration of Goupi Gao for 90 days can increase the renal indicator and levels of NAG in urine, enhance the accumulation of lead in renal, but with no effect on excretory function of kidneys and organic changes.

  19. Cloverleaf domain patterns in multiferroic RMnO3 (R = Ho, Er, and Lu)

    Science.gov (United States)

    Horibe, Y.; Chae, S. C.; Lee, N.; Cheong, S.-W.

    2011-03-01

    Hexagonal RMn O3 (R=rare earths) exhibits a unique improper ferroelectricity induced by structural trimerization. Intriguing domain pattern associated with ferroelectricity and trimerization, so-called ``cloverleaf'' domain pattern, has been reported in YMn O3 In this talk, we will report the domain structures in a series of RMn O3 with different rare earth elements, obtained from the results of our transmission electron microscopy. Characteristic cloverleaf domain patterns are clearly observed in RMn O3 (R = Ho, Er, and Lu). The results imply that the cloverleaf domain pattern is a common domain feature in the hexagonal manganites.

  20. Observation of the $^1$S$_0$ to $^3$D$_1$ clock transition in $^{175}$Lu$^+$

    CERN Document Server

    Arnold, Kyle J; Roy, A; Paez, E; Wang, S; Barrett, M D

    2016-01-01

    We report the first laser spectroscopy of the $^1$S$_0$ to $^3$D$_1$ clock transition in $^{175}$Lu$^+$. Clock operation is demonstrated on three pairs of Zeeman transitions, one pair from each hyperfine manifold of the $^3$D$_1$ term. We measure the hyperfine intervals of the $^3$D$_1$ to 10 ppb uncertainty and infer the optical frequency averaged over the three hyperfine transitions to be 353.639 915 952 2 (6) THz. The lifetime of the $^3$D$_1$ state is inferred to be $174^{+23}_{-32}$ hours from the M1 coupling strength.

  1. Şerefeddin Sabuncuoğlu: Forgotten Vignette of 600 Years

    Directory of Open Access Journals (Sweden)

    Murat Dıramalı

    2014-05-01

    Full Text Available Şereffeddin Sabuncuoğlu (1385-1465 was a surgeon who lived in Amasya in Ottoman Era. He was a good calligrapher and illustrator also as we saw from his works he could speak Arabic, Persian and Greek. He wrote the first treatise with colored illustrations entitled “Cerrahiyet’ül-Haniyye” with his own drawings. Mistakenly considered to be a translation of al-Zahrawi’s book but a careful analysis shows that there are 137 different observations and suggestions. He made several contributions in proctology, cancer treatment and neurosurgery. This report aims to investigate his contributions anatomy.

  2. Coherent acoustic phonons in hexagonal manganite LuMnO3

    Science.gov (United States)

    Lim, D.; Averitt, R. D.; Demsar, J.; Taylor, A. J.; Hur, N.; Cheong, S. W.

    2003-12-01

    We have observed coherent acoustic phonons in the hexagonal manganite LuMnO3 using two-color femtosecond optical pump-probe spectroscopy. The dependence of the oscillatory component of the photoinduced reflectivity on the probe wavelength and incident angle is consistent with a propagating strain pulse. Moreover, the frequency, dephasing, and phase of the oscillation are found to be temperature dependent. In particular, a large phase shift occurs in the vicinity of the Néel temperature (TN), which we relate to the temperature-dependent on-site Mn d-d transition that is coupled to antiferromagnetic ordering, as recently observed in optical conductivity measurements.

  3. Magnetic domains in the ferromagnetic and ferroelectric mixture of (La, Lu, Sr)MnO3

    Science.gov (United States)

    de Lozanne, Alex; Hur, N.

    2005-03-01

    Single crystals of (La5/8Sr3/8MnO3)x(LuMnO3)1-x (LSMO)(LMO) synthesized by the floating-zone method were studied by Magnetic Force Microscopy (MFM). Samples were mechanically cut and polished with the surface normal to the growth direction. Polarized optical microscopy shows that LSMO and LMO are separated in a stripe-like pattern due to the chemical immiscibility.ootnotetextS. Park, et al., PRL 92, 167206 (2004) MFM images show magnetic domains (˜1μm) in the LSMO stripes and no magnetic signal in the LMO phase.

  4. Intertwining of Frustration with Magneto-Elastic Coupling in the Multiferroic LuMnO3

    Science.gov (United States)

    Yano, Shin-ichiro; Louca, Despina; Chi, Songxue; Matsuda, Masaaki; Qiu, Yiming; Copley, John R. D.; Cheong, Sang-Wook

    2014-02-01

    Residual magnetic frustration in the multiferroic LuMnO3 may be key towards understanding magneto-elastic coupling in hexagonal manganites. Critical magnetic scattering present well above the magnetic ordering temperature TN persists below, as observed by inelastic neutron scattering. The magnetic fluctuations are confined in two dimensions implied by the characteristic wavevector dependence of the magnetic structure factor that changes from symmetric to asymmetric across TN. The low dimensionality of the magnetic structure is also evident in the temperature dependence of the commensurate antiferromagnetic intensity which follows a mean field exponent of β ˜ 0.2.

  5. Multiferroic Properties of o-LuMnO3 Controlled by b-Axis Strain

    Science.gov (United States)

    Windsor, Y. W.; Huang, S. W.; Hu, Y.; Rettig, L.; Alberca, A.; Shimamoto, K.; Scagnoli, V.; Lippert, T.; Schneider, C. W.; Staub, U.

    2014-10-01

    Strain is a leading candidate for controlling magnetoelectric coupling in multiferroics. Here, we use x-ray diffraction to study the coupling between magnetic order and structural distortion in epitaxial films of the orthorhombic (o-) perovskite LuMnO3. An antiferromagnetic spin canting in the E-type magnetic structure is shown to be related to the ferroelectrically induced structural distortion and to a change in the magnetic propagation vector. By comparing films of different orientations and thicknesses, these quantities are found to be controlled by b-axis strain. It is shown that compressive strain destabilizes the commensurate E-type structure and reduces its accompanying ferroelectric distortion.

  6. Strain-Induced Ferromagnetism in Antiferromagnetic LuMnO3 Thin Films

    Science.gov (United States)

    White, J. S.; Bator, M.; Hu, Y.; Luetkens, H.; Stahn, J.; Capelli, S.; Das, S.; Döbeli, M.; Lippert, Th.; Malik, V. K.; Martynczuk, J.; Wokaun, A.; Kenzelmann, M.; Niedermayer, Ch.; Schneider, C. W.

    2013-07-01

    Single phase and strained LuMnO3 thin films are discovered to display coexisting ferromagnetic and antiferromagnetic orders. A large moment ferromagnetism (≈1μB), which is absent in bulk samples, is shown to display a magnetic moment distribution that is peaked at the highly strained substrate-film interface. We further show that the strain-induced ferromagnetism and the antiferromagnetic order are coupled via an exchange field, therefore demonstrating strained rare-earth manganite thin films as promising candidate systems for new multifunctional devices.

  7. Intertwining of Frustration with Magneto-Elastic Coupling in the Multiferroic LuMnO3

    Energy Technology Data Exchange (ETDEWEB)

    Yano, Shin-ichiro [University of Virginia; Louca, Despina [University of Virginia; Chi, Songxue [ORNL; Matsuda, Masaaki [ORNL; Copley, John R. D. [National Institute of Standards and Technology (NIST), Gaithersburg, MD; Cheong, Sang-Wook [Rutgers University

    2014-01-01

    Residual magnetic frustration in the multiferroic LuMnO3 may be key towards understanding magneto-elastic coupling in hexagonal manganites. Critical magnetic scattering present well above the magnetic ordering temperature TN persists below, as observed by inelastic neutron scattering. The magnetic fluctuations are confined in two dimensions implied by the characteristic wavevector dependence of the magnetic structure factor that changes from symmetric to asymmetric across TN. The low dimensionality of the magnetic structure is also evident in the temperature dependence of the commensurate antiferromagnetic intensity which follows a mean field exponent of 0.2.

  8. Inadequate prenatal care utilization and associated factors in São Luís, Brazil

    OpenAIRE

    Bernardes,Ariane Cristina Ferreira; da Silva, Raimundo Antonio; Coimbra,Liberata Campos; Alves, Maria Teresa Seabra Soares de Britto; Queiroz,Rejane Christine de Sousa; Batista,Rosângela Fernandes Lucena; Bettiol,Heloisa; Barbieri,Marco Antônio; da Silva, Antônio Augusto Moura

    2014-01-01

    Background Over the last decades there has been a reduction of social inequalities in Brazil, as well as a strong expansion of health services, including prenatal care. The objective of the present study was to estimate the rate of inadequate prenatal care utilization and its associated factors in São Luís, Brazil, in 2010 and to determine whether there was a reduction of inequity in prenatal care use by comparing the present data to those obtained from a previous cohort started in 1997/98. M...

  9. Balet v luči dijakov Konservatorija za glasbo in balet v Mariboru

    OpenAIRE

    Kmetec, Breda

    2016-01-01

    Diplomsko delo z naslovom Balet v luči dijakov Konservatorija za glasbo in balet v Mariboru smo v začetku predstavili s krajšim teoretičnim pregledom zgodovine plesa skozi obdobja. Več pozornosti smo v nadaljevanju namenili baletni umetnosti. Predstavili smo balet od izvora do 20. stoletja, oblačila v baletu, ki so se skozi obdobja spreminjala, baletni prostor, ki je ključnega pomena za učenje in poučevanje baleta. Nato smo teoretični del diplomskega dela smiselno povezali z empiričnim, zato ...

  10. High power, high repetition rate, few picosecond Nd:LuVO₄ oscillator with cavity dumping.

    Science.gov (United States)

    Gao, Peng; Guo, Jie; Li, Jinfeng; Lin, Hua; Yu, Haohai; Zhang, Huaijin; Liang, Xiaoyan

    2015-12-28

    We investigate the potential use of Nd:LuVO4 in high average power, high repetition rate ultrafast lasers. Maximum mode-locked average power of 28 W is obtained at the repetition rate of 58 MHz. The shortest pulse duration is achieved at 4 ps without dispersion compensation. With a cavity dumping technique, the pulse energy is scaling up to 40.7 μJ at 300 kHz and 14.3 μJ at 1.5 MHz.

  11. Measurement of the half-life of sup 1 sup 7 sup 6 Lu

    CERN Document Server

    Nir-El, Y

    1998-01-01

    The half-life of sup 1 sup 7 sup 6 Lu was determined by measuring the disintegration rate of a solution of lutetium oxide, using a calibrated HPGe detector, and found to be (3.69+-0.02)x10 sup 1 sup 0 y. It is recommended that the current adopted value be calculated from the grouping of three published values since 1983, including our value, the weighted mean of which is (3.73+-0.01)x10 sup 1 sup 0 y.

  12. Afterglow, low-temperature radioluminescence and thermoluminescence of Lu 2O 3:Eu ceramic scintillators

    Science.gov (United States)

    Kappers, L. A.; Bartram, R. H.; Hamilton, D. S.; Brecher, C.; Lempicki, A.

    2005-01-01

    Comparison of thermoluminescence (TL) and scintillation light outputs with continuous gamma-ray excitation reveals that the concentration of deep hole traps in ceramic Lu2O3:Eu, tentatively attributed to anion Frenkel defects, is enhanced by reversible radiation damage. Shallow electron and hole traps are tentatively attributed to surface states at grain boundaries. Electrons in shallow traps serve as non-radiative recombination centers. A model for anomalously persistent afterglow following pulsed X-ray excitation is based on a continuous distribution of hole traps inferred from TL following extended gamma-ray irradiation at -135 °C.

  13. Luminescence properties of Lu2O3: Tb film prepared by Pechini sol-gel method

    Science.gov (United States)

    Shen, Siqing; Wang, Jian; Xu, Zhibin; Xie, Jianjun; Shi, Ying

    2011-02-01

    Uniform and crack free Tb3+ doped lutetium oxide (Lu2O3:Tb) films were prepared by Pechini sol-gel method combined with the spin-coating technique. The influence of the different substrate (monocrystalline silicon (111) and silica glass) and atmosphere (N2 and Air) on the luminescence properties of films was investigated. According to the emission spectra, we found that the luminous intensity was higher on silica glass substrate. Moreover, it was found that the luminous intensity calcined in N2 was higher almost twice as that calcined in air.

  14. Structure refinement of Lu{sub 2}WO{sub 6} and luminescent properties of Eu{sup 3+}, Pr{sup 3+} doped Lu{sub 2}WO{sub 6}

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Zhijun; Zhang Hui; Duan Chengjun; Yuan Junlin; Wang Xiaojun; Xiong Dingbang; Chen Haohong [State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050 (China); Graduate School of Chinese Academy of Science, Beijing (China); Zhao Jingtai [State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050 (China)], E-mail: jtzhao@mail.sic.ac.cn

    2008-10-20

    The crystal structure of Lu{sub 2}WO{sub 6} was determined from Rietveld refinement of X-ray powder diffraction data. It crystallizes in the monoclinic system belonging to space group P2/c (No.13) with lattice parameters: a = 7.5180(1) A, b = 5.2675(1) A, c = 11.2245(2) A, {beta} = 104.61(0){sup o}, V = 430.14(11) A{sup 3}, Z = 4. The conventional R indices obtained are R{sub p} = 0.090, R{sub wp} = 0.119 and R{sub B} = 0.075. The infinite chain comprised of Lu(2)O{sub 8} dodecahedra and Lu(3)O{sub 7} decahedra makes up the layer A, and the infinite straight chain is built of four-ring of polyhedra in which the WO{sub 6} and Lu(1)O{sub 8} groups alternate in layer B, finally, this structure is formed by stacking of these two layers with edge-shared. The X-ray and UV excited luminescence properties of Eu{sup 3+} and Pr{sup 3+} in Lu{sub 2}WO{sub 6} were investigated: Eu{sup 3+} shows high luminescent efficiency in emitting red light, and Pr{sup 3+} is less efficient in emitting orange light. The luminescent mechanism of Eu{sup 3+} and Pr{sup 3+} in the matrix of Lu{sub 2}WO{sub 6} is much different.

  15. Near-infrared to visible upconversion in Er3+ doped Cs3Lu2Cl9, Cs3Lu2Br9, and Cs3Y2I9 excited at 1.54 µm

    NARCIS (Netherlands)

    Lüthi, Stefan R.; Pollnau, Markus; Güdel, Hans U.; Hehlen, Markus P.

    1999-01-01

    A detailed study of upconversion processes in Cs3Er2X9 (X = Cl, Br, I) crystals and in the diluted systems Cs3Lu2Cl9:1% Er3+, Cs3Lu2Br9:1% Er3+, and Cs3Y2I9:1% Er3+ is presented. Efficient two-, three-, and four-step upconversion excitation along the sequence 4I15/2 4I13/2 4I9/2 4S3/2 2H9/2

  16. Investigation of magnetic structure evolution in the substitutional solid solution ScxLu(1-x)MnO3

    Science.gov (United States)

    Bieringer, M.; Greedan, J. E.; Wills, A. S.

    The hexagonal series AMnO3 (A = Lu, Sc) (space group: P63cm) is an excellent model system for the investigation of magnetic frustration as the magnetic sublattice is made up of edge sharing triangles with nearest neighbour antiferromagnetic exchange. At low temperatures the Mn3+ moments form a 120° long range ordered state. In LuMnO3 (TN=91 K) the magnetic moments are in the ab-plane and perpendicular to the hexagonal axis, whereas ScMnO3 (TN=130 K) undergoes an in-plane spin-reorientation transition below T=70 K. Powder neutron diffraction experiments for the substitutional solid solution ScxLu(1-x)MnO3 (0.0<=x<=1.0) show the evolution of the spin-reorientation as a function of x.

  17. Evaluation of (177)Lu-CHX-A''-DTPA-Bevacizumab as a radioimmunotherapy agent targeting VEGF expressing cancers.

    Science.gov (United States)

    Kameswaran, Mythili; Pandey, Usha; Gamre, Naresh; Vimalnath, K V; Sarma, Haladhar Dev; Dash, Ashutosh

    2016-08-01

    This study aimed at the preparation and evaluation of (177)Lu-CHX-A''-DTPA-Bevacizumab for targeting VEGF over-expressing cancers. Bevacizumab conjugated to p-NCS-Bn-CHX-A''-DTPA was radiolabeled with (177)Lu. The radioimmunoconjugate characterized by SE-HPLC exhibited radiochemical purity of 98.0±0.6%. In vitro stability was retained upto 4 days at 37°C. In vitro cell binding studies showed good uptake by VEGF expressing U937 tumor cells. Biodistribution studies in melanoma model showed significant uptake and retention of (177)Lu-CHX-A''-DTPA-Bevacizumab in tumor with reduction in uptake in presence of cold Bevacizumab confirming its specificity to VEGF. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Synthesis, Tunable Multicolor Output, and High Pure Red Upconversion Emission of Lanthanide-Doped Lu2O3 Nanosheets

    Directory of Open Access Journals (Sweden)

    Lingzhen Yin

    2013-01-01

    Full Text Available Yb3+ and Ln3+ (Ln = Er, Ho codoped Lu2O3 square nanocubic sheets were successfully synthesized via a facile hydrothermal method followed by a subsequent dehydration process. The crystal phase, morphology, and composition of hydroxide precursors and target oxides were characterized by X-ray diffraction (XRD, field emission scanning electron microscope (FE-SEM, and energy-dispersive X-ray spectroscope (EDS. Results present the as-prepared Lu2O3 crystallized in cubic phase, and the monodispersed square nanosheets were maintained both in hydroxide and oxides. Moreover, under 980 nm laser diode (LD excitation, multicolor output from red to yellow was realized by codoped different lanthanide ions in Lu2O3. It is noteworthy that high pure strong red upconversion emission with red to green ratio of 443.3 of Er-containing nanocrystals was obtained, which is beneficial for in vivo optical bioimaging.

  19. Comparative Efficacy of 177Lu and 90Y for Anti-CD20 Pretargeted Radioimmunotherapy in Murine Lymphoma Xenograft Models

    Energy Technology Data Exchange (ETDEWEB)

    Frost, Sophia; Frayo, Shani; Miller, Brian W.; Orozco, Johnnie J.; Booth, Garrett C.; Hylarides, Mark; Lin, Yukang; Green, Damian J.; Gopal, Ajay K.; Pagel, John M.; Back, Tom; Fisher, Darrell R.; Press, Oliver W.

    2015-03-01

    Pretargeted radioimmunotherapy (PRIT) is a multi-step method of selectively delivering high doses of radiotherapy to tumor cells while minimizing exposure to surrounding tissues. Yttrium-90 (90Y) and lutetium-177 (177Lu) are two of the most promising beta-particle emitting radionuclides used for radioimmunotherapy, which despite having similar chemistries differ distinctly in terms of radiophysical features. These differences may have important consequences for the absorbed dose to tumors and normal organs. Whereas 90Y has been successfully applied in a number of preclinical and clinical radioimmunotherapy settings, there have been few published pretargeting studies with 177Lu. We therefore compared the therapeutic potential of targeting either 90Y or 177Lu to human B-cell lymphoma xenografts in mice.

  20. Linear analysis on the stability of lanthanide vapor complexes LnAl3Cli2(Ln = La to Lu)

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    The reactions LnCl3 (s) + (3/2)Al2Cl6 (g) = LnAl3Cl12 (g) for Ln = La to Lu were studied by quenching experi-ments in roughly the same temperature and pressure ranges (588-851 K and 0.01-0.22 MPa). Stability constants Kθ oflanthanide complexes LnAl3Cl12 were calculated from the measurements. The values of lg Kθ change linearly with theionpotential (Z+/r) of lanthanide(Ⅲ) from La to Gd and from Tb to Lu, respectively, indicating the Gd break. There exist in-clined W effect between lg Kθ and the total angular momentum L of lanthanide(Ⅲ). And hereby lanthanide elements aredivided into four segments, La-Nd, Pm-Gd, Tb-Ho, and Er-Lu. In each segment, the linearity is maintained.

  1. Lu1-xI3:Cex--A Scintillator for gamma ray spectroscopy and time-of-flight PET

    Science.gov (United States)

    Shah, Kanai S.

    2009-03-17

    The present invention concerns very fast scintillator materials comprising lutetium iodide doped with Cerium Lu.sub.1-xI.sub.3:Ce.sub.x; LuI.sub.3:Ce). The LuI.sub.3 scintillator material has surprisingly good characteristics including high light output, high gamma ray stopping efficiency, fast response, low cost, good proportionality, and minimal afterglow that the material is useful for gamma ray spectroscopy, medical imaging, nuclear and high energy physics research, diffraction, non-destructive testing, nuclear treaty verification and safeguards, and geological exploration. The timing resolution of the scintillators of the present invention provide compositions capable of resolving the position of an annihilation event within a portion of a human body cross-section.

  2. 177 Lu-Dota-octreotate radionuclide therapy of advanced gastrointestinal neuroendocrine tumors: results from a phase II study

    Energy Technology Data Exchange (ETDEWEB)

    Paganelli, Giovanni; Sansovini, Maddalena; Ambrosetti, Alice; Severi, Stefano; Ianniello, Annarita; Matteucci, Federica [Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Nuclear Medicine and Radiometabolic Units, Meldola, FC (Italy); Monti, Manuela; Scarpi, Emanuela [IRST IRCCS, Unit of Biostatistics and Clinical Trials, Meldola (Italy); Donati, Caterina [IRST IRCCS, Oncology Pharmacy Laboratory, Meldola (Italy); Amadori, Dino [IRST IRCCS, Department of Medical Oncology, Meldola (Italy)

    2014-10-15

    We evaluated the activity and safety profile of {sup 177}Lu-Dotatate peptide receptor radionuclide therapy (Lu-PRRT) in patients with advanced, well-differentiated (G1-G2) gastrointestinal neuroendocrine tumors (GI-NETs). Forty-three patients with radiological tumor progression at baseline and a positive Octreoscan registered completed the treatment with Lu-PRRT, resulting in the cumulative activity of 18.5 or 27.8 GBq in five cycles. Total activity was scheduled on the basis of kidney function or bone marrow reserve. Twenty-five (58 %) patients were treated with a ''standard'' Lu-PRRT full dosage (FD) of 25.7 GBq (range 22.2-27.8), while the remaining 18 patients (42 %) who, at enrolment, showed a higher probability of developing kidney or bone marrow toxicity received a reduced dosage (RD) of 18.4 GBq (range 14.4-20.4). According to SWOG criteria, the overall response was complete response (CR) in (7 %) cases and stable disease (SD) in 33 (77 %), with a disease control rate (DCR) of 84 %. Median response duration was 25 months (range 7-50). Median progression-free survival (PFS) was 36 months (95 % CI 24-nr), and median overall survival (OS) has not yet been reached. Remarkably, none of the patients, including those at a higher risk of toxicity, showed side-effects after either dosage of Lu-PRRT. Lu-PRRT was shown to be an effective therapeutic option in our patients with advanced progressive GI-NETs, showing an 84 % DCR (95 % CI 73-95) that lasted for 25 months and a PFS of 36 months. Both activities of 27.8 GBq and 18.5 GBq proved safe and effective in all patients, including those with a higher probability of developing kidney or bone marrow toxicity. (orig.)

  3. Lu Xun and Anti-Christian Movement%鲁迅与非基督教运动

    Institute of Scientific and Technical Information of China (English)

    杨世海

    2013-01-01

    The Anti-Christian movement in 192−1927 was an important social and political movement after the May Fourth Movement. Most of the cultural elite involved in the movement, but Lu Xun did not directly participate in it, and the reason is worth exploring. Lu Xun did not intervene in the movement, but the movement was still affected Lu Xun’s attitude towards Christianity, which not only let Lu Xun changed his mind to Christianity, but also cut off the possibility that Lu Xun might realize the Christian holy transcendent value, which, in turn, might directly affect the depth and direction of Lu Xun's ideas and literary creation.%  1922−1927年的非基督教运动是继五四运动后又一次规模巨大的社会政治运动,当时大多数文化精英都介入了这一运动,但鲁迅并未直接参与,其中缘由值得探讨。鲁迅虽未介入这一运动,但仍然受到影响,他对基督教的态度由此发生变化,鲁迅走向基督教神圣超越价值的可能断绝,也就直接影响到鲁迅思想和文学创作的深度和方向。

  4. An Improved LU-SGS Implicit Scheme for High Reynolds Number Flow Computations on Hybrid Unstructured Mesh

    Institute of Scientific and Technical Information of China (English)

    WANG Gang; JIANG Yuewen; YE Zhengyin

    2012-01-01

    The lower-upper symmetric Gauss-Seidel (LU-SGS) implicit relaxation has been widely used because it has the merits of less dependency on grid topology,low numerical complexity and modest memory requirements.In original LU-SGS scheme,the implicit system matrix is construeted based on the splitting of convective flux Jacobian according to its spectral radius.Although this treatment has the merit of reducing computational complexity and helps to ensure the diagonally dominant property of the implicit system marx,it can also cause serious distortions on the implicit system matrix because too many approximations are introduced by this splitting method if the contravariant velocity is small or close to sonic speed.To overcome this shortcoming,an improved LU-SGS scheme with a hybrid construction method for the implicit system matrix is developed in this paper.The hybrid way is that:on the cell faces having small contravariant velocity or transonic contravariant velocity,the accurate derivative of the convective flux term is used to construct more accurate implicit system matrix,while the original Jacobian splitting method is adopted on the other cell faces to reduce computational complexity and ensure the diagonally dominant property of the implicit system matrix.To investigate the convergence performance of the improved LU-SGS scheme,2D and 3D turbulent flows around the NACA0012 airfoil,RAE2822 airfoil and LANN wing are simulated on hybrid unstructured meshes.The numerical results show that the improved LU-SGS scheme is significantly more efficient than the original LU-SGS scheme.

  5. A systematic study on the utility of CHX-A''-DTPA-NCS and NOTA-NCS as bifunctional chelators for (177)Lu radiopharmaceuticals.

    Science.gov (United States)

    Pandey, Usha; Gamre, Naresh; Lohar, Sharad Pandurang; Dash, Ashutosh

    2017-09-01

    This paper describes the evaluation of [(R)-2-Amino-3-(4-isothiocyanatophenyl)propyl]-trans-(S,S)-cyclohexane-1,2-diamine-pentaacetic acid (CHX-A''-DTPA-NCS) and 2-S-(4-isothiocyanatobenzyl)-1,4,7-triazacyclononane-1,4,7-triacetic acid (NOTA-NCS) as bifunctional chelators for (177)Lu. While (177)Lu-CHX-A''-DTPA-NCS could be obtained in high yields at equimolar ratios of lutetium to CHX-A''-DTPA-NCS, >95% yield of (177)Lu-NOTA-NCS could be achieved at 1:2M ratio of lutetium to NOTA-NCS. Trace metals reduced the yields of (177)Lu-NOTA-NCS significantly as compared to (177)Lu-CHX-A''-DTPA-NCS. In vitro stability of (177)Lu-CHX-A''-DTPA-NCS was also superior to (177)Lu-NOTA-NCS. It could be concluded from this study that among the two chelators evaluated, CHX-A''-DTPA-NCS is more appropriate for preparation of (177)Lu radiopharmaceuticals. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. The pseudogap and anisotropic thermal expansion in RMn(4)Al(8) (R = La,Y,Lu and Sc).

    Science.gov (United States)

    Muro, Y; Nakamura, H; Kohara, T

    2006-04-26

    The temperature dependence of the magnetic susceptibility shows a broad maximum at ∼550 and 630 K for LuMn(4)Al(8) and ScMn(4)Al(8), respectively, which can be interpreted as due to the presence of a pseudogap in the effective bands as in LaMn(4)Al(8) and YMn(4)Al(8). The anisotropic thermal expansion observed for RMn(4)Al(8) (R = La, Y, Lu and Sc) and the sensitive volume dependence of the gap width throughout the RMn(4)Al(8) system suggest dominant magnetic coupling in Mn spin chains along the c axis.

  7. Risk factors for preterm births in São Luís, Maranhão, Brazil

    OpenAIRE

    Aragão Vânia Maria de Farias; Silva Antônio Augusto Moura da; Aragão Lívia Farias de; Barbieri Marco Antônio; Bettiol Heloísa; Coimbra Liberata Campos; Ribeiro Valdinar Sousa

    2004-01-01

    Preterm birth continues to be one of the main causes of neonatal morbidity and mortality. The objective of the present study was to identify risk factors for preterm birth in São Luís, Maranhão, Brazil. The sample consisted of hospital births at 10 public and private hospitals from March 1, 1997 to February 28, 1998. A total of 2,443 live births were randomly selected, excluding multiple deliveries and stillbirths. Preterm birth rate in São Luís was 12.7%. Risk factors for preterm delivery we...

  8. Multispecies animal investigation on biodistribution, pharmacokinetics and toxicity of {sup 177}Lu-EDTMP, a potential bone pain palliation agent

    Energy Technology Data Exchange (ETDEWEB)

    Mathe, Domokos [Department of Applied Radioisotopes and Animal Experimentation, National ' Frederic Joliot-Curie' Institute of Radiobiology and Radiohygiene, H-1221 Budapest (Hungary)], E-mail: mdomokos@hp.osski.hu; Balogh, Lajos; Polyak, Andras; Kiraly, Reka [Department of Applied Radioisotopes and Animal Experimentation, National ' Frederic Joliot-Curie' Institute of Radiobiology and Radiohygiene, H-1221 Budapest (Hungary); Marian, Terez [Institute of Nuclear Medicine, Debrecen University, Debrecen (Hungary); Pawlak, Dariusz [Institute of Atomic Energy, Radioisotope Centre POLATOM, Swierk-Otwock (Poland); Zaknun, John J.; Pillai, Maroor R.A. [International Atomic Energy Agency (IAEA), Vienna (Austria); Janoki, Gyozo A. [Department of Applied Radioisotopes and Animal Experimentation, National ' Frederic Joliot-Curie' Institute of Radiobiology and Radiohygiene, H-1221 Budapest (Hungary)

    2010-02-15

    Introduction: Radionuclide therapy (RNT) is an effective method for bone pain palliation in patients suffering from bone metastasis. Due to the long half-life, easy production and relatively low {beta}- energy, {sup 177}Lu [T{sub 1/2}=6.73 days, E{sub {beta}}{sub max}=497 keV, E{sub {gamma}}=113 keV (6.4%), 208 keV (11%)]-based radiopharmaceuticals offer logistical advantage for wider use. This paper reports the results of a multispecies biodistribution and toxicity studies of {sup 177}Lu-EDTMP to collect preclinical data for starting human clinical trials. Methods: {sup 177}Lu-EDTMP with radiochemical purity greater than 99% was formulated by using a lyophilized kit of EDTMP (35 mg of EDTMP, 5.72 g of CaO and 14.1 mg of NaOH). Biodistribution studies were conducted in mice and rabbits. Small animal imaging was performed using NanoSPECT/CT (Mediso, Ltd., Hungary) and digital autoradiography. Gamma camera imaging was done in rabbits and dogs. Four levels of activity (9.25 through 37 MBq/kg body weight) of {sup 177}Lu-EDTMP were injected in four groups of three dogs each to study the toxicological effects. Results: {sup 177}Lu-EDTMP accumulated almost exclusively in the skeletal system (peak ca. 41% of the injected activity in bone with terminal elimination half-life of 2130 and 1870 h in mice and rabbits, respectively) with a peak uptake during 1-3 h. Excretion of the radiopharmaceutical was through the urinary system. Imaging studies showed that all species (mouse, rat, rabbit and dog) take up the compound in regions of remodeling bone, while kidney retention is not visible after 1 day postinjection (pi). In dogs, the highest applied activity (37 MBq/kg body weight) led to a moderate decrease in platelet concentration (mean, 160 g/L) at 1 week pi with no toxicity. Conclusion: The protracted effective half-life of {sup 177}Lu-EDTMP in bone supports that modifying the EDTMP molecule by introducing {sup 177}Lu does not alter its biological behaviour as a specific bone

  9. The Studies on Diurnal Butterflies (Lepidoptera: Rhopalocera in Canakkale Onsekiz Mart University Terzioğlu Campus

    Directory of Open Access Journals (Sweden)

    D. Zobar

    2008-09-01

    Full Text Available The purpose of the study is to determine lepidopteran species on Terzioğlu Campus during March 2005–April 2007. We surveyed Rhopalocera butterflies in Çanakkale Onsekiz Mart University, Terzioğlu Campus, in Çanakkale, Turkey. In this study, total of 44 species belonging to to Papilionidae (4, Nymphalidae (23, Pieridae (8, Lycaenidae (4 and Hesperiidae (5, were identified. The most abundant species throughout the campus are Pieris brassicae, P. rapae, P. napi, Colias crocea, Iphiclides podalirius, and Melanargia larissa.

  10. A new edge-preserving algorithm based on the CIE- Lu'v' color space for color contrast enhancement

    OpenAIRE

    ZOLFAGHARI, Mohammad; Yazdi, Mehran

    2014-01-01

    Image segmentation and edge detection are the most important presteps in machine vision, and their successfulness can affect the success of the next steps. In this paper, the performance of the Trahanias edge detector in different color spaces, such as RGB, YCbCr, HSI, and CIE Lu'v', is compared in order to find the best color space for image segmentation and edge detection. We then offer an efficient edge-preserving algorithm for color contrast enhancement in the CIE Lu'...

  11. First principle study of AlX (X=3d, 4d, 5d elements and Lu) dimer.

    Science.gov (United States)

    Ouyang, Yifang; Wang, Jianchuan; Hou, Yuhua; Zhong, Xiaping; Du, Yong; Feng, Yuanping

    2008-02-21

    The ground state equilibrium bond length, harmonic vibrational frequency, and dissociation energy of AlX (X=3d,4d,5d elements and Lu) dimers are investigated by density functional method B3LYP. The present results are in good agreement with the available experimental and other theoretical values except the dissociation energy of AlCr. The present calculations show that the late transition metal can combine strongly with aluminum compared with the former transition metal. The present calculation also indicates that it is more reasonable to replace La with Lu in the Periodic Table and that the bonding strengths of zinc, cadmium, and mercury with aluminum are very weak.

  12. Temperature dependent PAC studies with the rare earth '$^{172}$Lu' in ZnO

    CERN Document Server

    Nédélec, R

    2006-01-01

    Wide band-gap semiconductors have become an important base material for applications in optoelectronics and in high power, high temperature electronics. After doping with various rare earths, electroluminescence throughout the whole visible spectrum has been observed. We have studied the implantation behaviour of the rare earth Lu in ZnO. Our samples were implanted at the ISOLDE facility at CERN. In order to recover the sustained implantation damage the samples were treated in a rapid thermal annealing furnace. In a first attempt to measure the temperature dependence of the electric field gradient at the site of 172Lu/172Yb in ZnO a large jump in the quadrupole interaction frequency was observed between measurements at room temperature and 200 °C. Above 200 °C the frequency only changed very little. In order to understand this unusual behaviour we prepared another sample and studied the temperature range between room temperature and 200 °C in more detail. The results obtained previously could be confirmed....

  13. Characterization of 176Lu background in LSO-based PET scanners

    Science.gov (United States)

    Conti, Maurizio; Eriksson, Lars; Rothfuss, Harold; Sjoeholm, Therese; Townsend, David; Rosenqvist, Göran; Carlier, Thomas

    2017-05-01

    LSO and LYSO are today the most common scintillators used in positron emission tomography. Lutetium contains traces of 176Lu, a radioactive isotope that decays β - with a cascade of γ photons in coincidence. Therefore, Lutetium-based scintillators are characterized by a small natural radiation background. In this paper, we investigate and characterize the 176Lu radiation background via experiments performed on LSO-based PET scanners. LSO background was measured at different energy windows and different time coincidence windows, and by using shields to alter the original spectrum. The effect of radiation background in particularly count-starved applications, such as 90Y imaging, is analysed and discussed. Depending on the size of the PET scanner, between 500 and 1000 total random counts per second and between 3 and 5 total true coincidences per second were measured in standard coincidence mode. The LSO background counts in a Siemens mCT in the standard PET energy and time windows are in general negligible in terms of trues, and are comparable to that measured in a BGO scanner of similar size.

  14. Electric Field Effect on the Magnetic Order in Multiferroic LuMnO3

    Science.gov (United States)

    Duan, Chunruo; Yang, Junjie; Harriger, Leland; Louca, Despina

    LuMnO3 belongs to the family of hexagonal multiferroics in which ferroelectric and magnetic orders coexist and compete. The Mn3+ ions reside on a triangular lattice that is geometrically frustrated but undergoes a Neel transition at TN ~90 K. Neutron experiments under electric field were carried out on a single crystal of LuMnO3 at SPINS to investigate the coupling of the electric field to the magnetic order. The elastic and inelastic scattering around the commensurate (101) magnetic peak and the Mn trimerization induced (100) peak with and without electric field were investigated. When applying an E-field of 13.3 kV/cm along the (001) direction on an unpoled sample, an increase in (101) peak as well as a shift of the inelastic excitation near (100) to higher ΔE have been observed. Once the sample is polarized, these effects exist without the field. On the other hand, an E-field along (110) direction shows almost no effect. The spin arrangement of the magnetic order is within the ab-plane, thus the Dzyaloshinskii-Moriya interaction explains why a polarization perpendicular to the magnetic moment gives a larger effect. The implication will be discussed.

  15. Magnon breakdown in a two dimensional triangular Heisenberg antiferromagnet LuMnO3

    Science.gov (United States)

    Oh, Joosung; Le, Manh-Duc; Jeong, Jaehong; Park, Je-Geun; Lee, Jung-Hyun; Song, Wan-Young; Perring, T. G.; Woo, Hyungje; Buyers, W. J. L.; Cheong, S.-W.

    2014-03-01

    Magnons, the quasi-particles of long range ordered magnetic systems, have long been viewed as long lived excitations with spectra that are well described by linear spin wave theory (LSWT). Recent theoretical works, though, suggest that the magnon spectrum of 2D triangular Heisenberg antiferromagnet (THA) is highly renormalized downward with a roton-like minimum at the M point. This, as well as the decay of single magnons into two magnon states, was interpreted as the effects of a cubic interaction between magnons arising from the noncollinear spin structure LuMnO3 is a good 2D THA candidate to test this prediction since it has a noncollinear 120° spin structure with S =2. We have conducted inelastic neutron scattering experiments using a LuMnO3 single crystal. Much of the observed spectrum is well described by LSWT, but, a closer inspection of the M point show deviations: a minimum at the lowest energy mode, a flat dispersion at upper modes and line width broadening at the top of the dispersion due to magnon decay. These features agree qualitatively with the theoretical predictions, revealing the importance of the cubic interaction between magnons in 2D THA

  16. Antiferromagnetic Resonance in Multiferroic YMnO3 and LuMnO3

    Science.gov (United States)

    Zvyagin, Sergei

    2009-03-01

    Multiferroic rare-earth manganites have attracted much attention because of the coexistence of ferroelectric and magnetic orders. Combining conventional far-infrared Fourier-transform and THz-range free electron laser electron spin resonance (ESR) spectroscopy techniques, magnetic excitations in hexagonal multiferroic YMnO3 and LuMnO3 in the antiferromagnetically (AFM) ordered phase have been studied. The gap in the excitation spectrum (˜42 and ˜48 cm-1 for YMnO3 and LuMnO3, respectively) was observed directly. Similar slope of the frequency-field dependences of AFM resonance modes, ˜ 0.5 cm-1/T, was revealed for both compounds. A fine structure of AFM resonance absorption has been revealed by means of high-resolution ESR techniques, which can be explained taking into account a finite interaction between the neighboring Mn^3+ layers. The work was done in collaboration with M. Ozerov, D. Kamensky, E. Cizm'ar, J. Wosnitza, A.K. Kolezhuk, D. Smirnov, H.D. Zhou, and C.R. Wiebe.

  17. Origin of room-temperature multiferroism in hexagonal LuFeO3

    Science.gov (United States)

    Wu, Xifan; Wang, Hongwei; Solovyev, Igor; Shen, Jian; Wang, Wenbin; Wang, Xiao; Cheng, Xuemei; He, Lixin; Xu, Xiaoshan

    2014-03-01

    Combined theoretical and experimental studies are carried out, focusing on the exchange interactions and their couplings with the structural instabilities in hexagonal LuFeO3 (hLFO). We apply an extended Kugel-Khomskii model based on maximally localized Wannier functions generated from band structure calculations. The model clearly shows that the single occupied dz2 orbital in hLFO greatly increases the exchange coupling compared to that of hexagonal LuMnO3 in which dz2 is empty. The interlayer exchange interaction is the key to the spin reorientation (SR) and weak ferromagnetic moment observed below 130K. Our calculations show that SR is strongly coupled to the K1 phonon mode and only weakly dependent on K3 and Γ2- phonons. It indicates that the atomic displacements along positive direction of K1 mode is responsible for the spin reorientation. This scenario is confirmed by our X-ray diffraction and X-ray absorption experiments. In the end, we propose that TSR can be adjusted to be room temperature by structural competition between K1 and Γ2- modes in hLFO or by interface engineering.

  18. Femtosecond laser excitation of coherent optical phonons in ferroelectric LuMnO3

    Science.gov (United States)

    Lou, Shi-Tao; Zimmermann, Frank M.; Bartynski, Robert A.; Hur, Namjung; Cheong, Sang-Wook

    2009-06-01

    We have used femtosecond pump-probe spectroscopy to excite and probe coherent optical phonon vibrations in single crystals of hexagonal ferroelectric LuMnO3 . An optical phonon mode of A1 symmetry was coherently excited with 25 fs pump-laser pulses (λ≈800nm) . The phonon mode, involving Lu ion motion along the c axis, was identified as the soft mode driving the ferroelectric transition. The excitation mechanism was determined to be purely displacive in nature due to resonant excitation of a narrow intra-atomic dxy,x2-y2→d3z2-r2 transition in Mn. The lifetime of the Mndxy,x2-y2→d3z2-r2 excitation was measured to be 0.8 ps. A remarkable reversal of the sign of the oscillation amplitude ( π phase shift) of the reflectivity curve was observed upon comparing longitudinal-optical (LO) with transverse-optical (TO) mode geometries. The phase reversal is attributed to the macroscopic electric depolarization field accompanying infrared-active longitudinal phonon modes but absent in TO modes. In addition to the direct effect of the ion motion on the optical properties, which is the same in LO and TO modes, the longitudinal depolarization field of the LO mode gives rise to an additional modulation of the refractive index via the linear electro-optic effect which dominates the optical response.

  19. Preparation and biological evaluation of {sup 177}Lu conjugated PR81 for radioimmunotherapy of breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    Salouti, Mojtaba, E-mail: saloutim@yahoo.com [Department of Biology, Faculty of Sciences, Zanjan Branch, Islamic Azad University, Zanjan 45156-58145 (Iran, Islamic Republic of); Babaei, Mohammad Hossein [Nuclear Biomolecule Laboratory, Radioisotope Department, Nuclear Science and Technology Research Institute, Tehran 14144-1339 (Iran, Islamic Republic of); Rajabi, Hossein [Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran 14115-111 (Iran, Islamic Republic of); Rasaee, Mohammad javad [Department of Medical Biotechnology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran 14115-111 (Iran, Islamic Republic of)

    2011-08-15

    Aim: PR81 is a monoclonal antibody that binds with high affinity to MUC1 antigen that is over expressed in 80% of breast cancers. In this study, we developed a method for indirect labeling of PR81 with lutetium-177 and performed all preclinical qualifications in production of a biologic agent for radioimmunotherapy of breast cancer. Materials and Methods: The radiochemical purity and in vitro stability of {sup 177}Lu labeled PR81 was determined by instant thin layer chromatography. The immunoreactivity and cell toxicity of the complex were tested on MCF7 cell line. The biodistribution and scintigraphy studies were performed in BALB/c mice with breast tumor. Results: The radiochemical purity was 91.2{+-}3.8% after 2 h. The in vitro stabilities in phosphate buffer and human blood serum were 83.1{+-}3.4% and 76.2{+-}3.6% at 96 h, respectively. The immunoreactivity of the complex was 83.4{+-}2.4%. The cell toxicity study showed that the complex inhibited 85.2{+-}3.4% growth of MCF7 cells at a concentration of 2500 ng/ml after 96 h. The biodistribution and scintigraphy studies showed the accumulation of the complex at the site of tumors with high sensitivity and specificity. Conclusion: The results showed that one may consider {sup 177}Lu-DOTA-PR81 as a potential radiopharmaceutical for therapy of human breast cancer, which needs further investigations.

  20. Advancing Control for Shield Tunneling Machine by Backstepping Design with LuGre Friction Model

    Directory of Open Access Journals (Sweden)

    Haibo Xie

    2014-01-01

    Full Text Available Shield tunneling machine is widely applied for underground tunnel construction. The shield machine is a complex machine with large momentum and ultralow advancing speed. The working condition underground is rather complicated and unpredictable, and brings big trouble in controlling the advancing speed. This paper focused on the advancing motion control on desired tunnel axis. A three-state dynamic model was established with considering unknown front face earth pressure force and unknown friction force. LuGre friction model was introduced to describe the friction force. Backstepping design was then proposed to make tracking error converge to zero. To have a comparison study, controller without LuGre model was designed. Tracking simulations of speed regulations and simulations when front face earth pressure changed were carried out to show the transient performances of the proposed controller. The results indicated that the controller had good tracking performance even under changing geological conditions. Experiments of speed regulations were carried out to have validations of the controllers.

  1. Realistic multi-cellular dosimetry for (177)Lu-labelled antibodies: model and application.

    Science.gov (United States)

    Marcatili, S; Pichard, A; Courteau, A; Ladjohounlou, R; Navarro-Teulon, I; Repetto-Llamazares, A; Heyerdahl, H; Dahle, J; Pouget, J P; Bardiès, M

    2016-10-07

    Current preclinical dosimetric models often fail to take account of the complex nature of absorbed dose distribution typical of in vitro clonogenic experiments in targeted radionuclide therapy. For this reason, clonogenic survival is often expressed as a function of added activity rather than the absorbed dose delivered to cells/cell nuclei. We designed a multi-cellular dosimetry model that takes into account the realistic distributions of cells in the Petri dish, for the establishment of survival curves as a function of the absorbed dose. General-purpose software tools were used for the generation of realistic, randomised 3D cell culture geometries based on experimentally determined parameters (cell size, cell density, cluster density, average cluster size, cell cumulated activity). A mixture of Monte Carlo and analytical approaches was implemented in order to achieve as accurate as possible results while reducing calculation time. The model was here applied to clonogenic survival experiments carried out to compare the efficacy of Betalutin(®), a novel (177)Lu-labelled antibody radionuclide conjugate for the treatment of non-Hodgkin lymphoma, to that of (177)Lu-labelled CD20-specific (rituximab) and non-specific antibodies (Erbitux) on lymphocyte B cells. The 3D cellular model developed allowed a better understanding of the radiative and non-radiative processes associated with cellular death. Our approach is generic and can also be applied to other radiopharmaceuticals and cell distributions.

  2. 精神分析学说与鲁迅%Psychoanalytic Theory and Lu Xun

    Institute of Scientific and Technical Information of China (English)

    韩志荣

    2012-01-01

    As a worldwide trend of thought, Psychoanalysis has an extensive and far--reaching impact on Chinese literary in the 20th century. Lu Xun's ideas and works have been affected by psychoanalysis, theory experienced a process from acceptance and absorption to analysis and .criticism. Then, elements as theoretical weapons, and used it to reveal social problems profoundly. This process the works of Lu Xun. and his he drew acceptance of the on the reasonable of change can be seen from%精神分析学说作为一种世界性思潮,对20世纪的中国文坛产生了广泛而深远的影响。鲁迅先生的思想和作品也曾受到精神分析学说的影响,并且对它的接受经历了一个过程,从接纳吸收到分析批判,再到借鉴其中的合理成分,作为战斗的武器,用它来深刻地揭示社会问题。这一转变过程我们从鲁迅先生的作品中可以看出。

  3. Realistic multi-cellular dosimetry for 177Lu-labelled antibodies: model and application

    Science.gov (United States)

    Marcatili, S.; Pichard, A.; Courteau, A.; Ladjohounlou, R.; Navarro-Teulon, I.; Repetto-Llamazares, A.; Heyerdahl, H.; Dahle, J.; Pouget, J. P.; Bardiès, M.

    2016-10-01

    Current preclinical dosimetric models often fail to take account of the complex nature of absorbed dose distribution typical of in vitro clonogenic experiments in targeted radionuclide therapy. For this reason, clonogenic survival is often expressed as a function of added activity rather than the absorbed dose delivered to cells/cell nuclei. We designed a multi-cellular dosimetry model that takes into account the realistic distributions of cells in the Petri dish, for the establishment of survival curves as a function of the absorbed dose. General-purpose software tools were used for the generation of realistic, randomised 3D cell culture geometries based on experimentally determined parameters (cell size, cell density, cluster density, average cluster size, cell cumulated activity). A mixture of Monte Carlo and analytical approaches was implemented in order to achieve as accurate as possible results while reducing calculation time. The model was here applied to clonogenic survival experiments carried out to compare the efficacy of Betalutin®, a novel 177Lu-labelled antibody radionuclide conjugate for the treatment of non-Hodgkin lymphoma, to that of 177Lu-labelled CD20-specific (rituximab) and non-specific antibodies (Erbitux) on lymphocyte B cells. The 3D cellular model developed allowed a better understanding of the radiative and non-radiative processes associated with cellular death. Our approach is generic and can also be applied to other radiopharmaceuticals and cell distributions.

  4. End-pumped all solid-state high repetition rate Tm, Ho:LuLF laser

    Institute of Scientific and Technical Information of China (English)

    Shijiang Shu; Ting Yu; Junyan Hou; Rongtao Liu; Minjie Huang; Weibiao Chen

    2011-01-01

    @@ The characteristics of diode end-pumped Tm,Ho:LuLiF for continuous wave (CW) running and high pulse repetition frequency (PRF) Q-switched operation are illustrated. In the CW mode, 950-mW output power with a slope efficiency of 24% is obtained. In the Q-switched mode, output energy of 78 μJ under 10 kHz with a slope efficiency of 23% is achieved. The pulse stability, pulse width as a function of pump intensity, and spectral characteristics are also analyzed.%The characteristics of diode end-pumped Tm,Ho:LuLiF for continuous wave (CW) running and high pulse repetition frequency (PRF) Q-switched operation are illustrated. In the CW mode, 950-mW output power with a slope efficiency of 24% is obtained. In the Q-switched mode, output energy of 78μJ under 10 kHz with a slope efficiency of 23% is achieved. The pulse stability, pulse width as a function of pump intensity, and spectral characteristics are also analyzed.

  5. Composition and hygroscopicity of aerosol particles at Mt. Lu in South China: Implications for acid precipitation

    Science.gov (United States)

    Li, Weijun; Chi, Jianwei; Shi, Zongbo; Wang, Xinfeng; Chen, Bin; Wang, Yan; Li, Tao; Chen, Jianmin; Zhang, Daizhou; Wang, Zifa; Shi, Chune; Liu, Liangke; Wang, Wenxing

    2014-09-01

    Physicochemical properties of aerosol particles were studied at Mt. Lu, an elevated site (115°59‧E, 29°35‧N, 1165 m) within the acid precipitation area. Northeast winds transport copious amounts of air pollutants and water vapor from the Yangtze River Delta into this acid precipitation area. NH4+ and SO42- are the dominant ions in PM2.5 and determine aerosol acidity. Individual particle analysis shows abundant S-rich and metals (i.e. Fe-, Zn-, Mn-, and Pb-rich) particles. Unlike aerosol particles in North China and urban areas, there are little soot and mineral particles at Mt. Lu. Lack of mineral particles contributed to the higher acidity in precipitation in the research area. Nano-sized spherical metal particles were observed to be embedded in 37% of S-rich particles. These metal particles were likely originated from heavy industries and fired-power plants. Hygroscopic experiments show that most particles start to deliquesce at 73-76% but organic coating lowers the particle deliquescence relative humidity (DRH) to 63-73%. The DRHs of these aerosol particles are clearly smaller than that of pure ammonium sulfate particles which is 80%. Since RH in ambient air was relatively high, ranging from 65% to 85% during our study period, most particles at our sampling site were in liquid phase. Our results suggest that liquid phase reactions in aerosol particles may contribute to SO2 to sulfuric acid conversion in the acid precipitation area.

  6. Reducing Renal Uptake of {sup 177}Lu Labeled CCK Derivative using Basic Amino Acids

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Soyoung; Lim, Jaecheong; Joh, Eunha [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-05-15

    Radiolabeled peptides have been designed to target the relative receptors overespressed in tumor cells, such as integrin αvβ3, gastrin-releasing peptide receptor (GRPR), melanocortin-1 receptor (MC1-R), glucagon-like peptide-a receptor (GLP-1R), and cholecystokinin (CCK) receptor. Most of these peptides are eliminated from the body via the kidney and are partly reabsorbed in the proximal tubular cells. However, the high renal uptake of the radiolabeled peptides may lead to renal toxicity. In this study we investigated various amino acid solutions to reduce the renal uptake of {sup 177}Lu-DOTA-CCK derivative. Renal uptake of {sup 177}Lu-DOTA-CCK derivative is effectively reduced by the administration of positively charged amino acids. The administration of 12 mg of L-lysine was as effective in reducing the renal uptake as 6 mg of lysine and 6 mg of arginine combinations. Further studies will be performed to identify the most potent inhibitor of renal reuptake of radiolabeled peptides and minimize the chance of unwanted side effects.

  7. Lu Huiniang

    Institute of Scientific and Technical Information of China (English)

    1994-01-01

    en Canruo estis bela jun-ulo.Mal-sanofor-prenis vivon de lia edz-ino(anka tre bela).Foje li vizitis allan urbon.Sur-voje li vidisbel-egan vir-inon.ia belo kaptis lin,ke linepovis vidi aliajn aferojn.Li tuj sekvis in.i detempo al tempo re-turn-iSis por vidi lin,kun

  8. The Defamiliarization Interpretation of Gao Zu's Return of the Native%《高祖还乡》的陌生化解读

    Institute of Scientific and Technical Information of China (English)

    夏艳萍

    2014-01-01

    “陌生化”意味着“使其陌生”,是俄国形式主义诗学的核心概念,它昭显了俄国形式主义的纯艺术观。以“陌生化”为基点,俄国形式主义构建了一个自主性的文学理论体系。在《高祖还乡》中,睢景臣通过陌生化的艺术处理,对传统的根深蒂固的文化正统和帝王权威进行了成功的颠覆,使接受主体摆脱了机械化的定势的感知模式,以一种全新的眼光和视角来体验、观照和审视历史。%As a core concept of poetics in Russian Formalism,“defamiliarization”means “making it strange”,which shows the purely artistic view of Russian Formalism.Taking “defamiliarization”as the base point,Russian Formalism has built an autonomously literary theory system.In Gao Zu's Return ofthe Native,Ju Jingchen,by means of artistic treatment of defamiliarization,successfully overthrew the traditionally deep-rooted cultural orthodox and the emperor's authority,made the reception subjects get rid of mechanical and rigid per-ceptual modes,and experienced,observed and examined the history with a new visual angle and perspective.

  9. 高希言教授八髎穴临床应用举隅%Clinical Application Examples of Acupoints Baliao by Professor Gao Xiyan

    Institute of Scientific and Technical Information of China (English)

    徐翠香; 高崚

    2012-01-01

    目的:探讨八髎穴在临床中用于治疗腹泻、便秘的临床疗效.方法:通过病例举证具体分析针刺八髎穴治疗腹泻、便秘的临床疗效.结果:八髎穴临床运用广泛,而现在临床上多用八髎穴来治疗腰痛及妇科疾病等,而较少用于其他方面,高希言教授根据多年临床经验,运用八髎穴治疗便秘、腹泻.结论:针灸八髎穴治疗便秘和腹泻疗效显著且无不良反应,并能从根本上改善症状.%Objective:To investigate the clinical efficacy of the acupoints Baliao in the clinical treatment of diarrhea and constipation. Methods: The clinical efficacy of acupuncturing acupoints Baliao for the treatment of diarrhea and constipation were given a concrete a-nalysis through case testification. Results: The clinical application of acupoints Baliao was in a wide range, and now they are applied mostly for the treatment of low back pain and gynecological diseases in clinical practice, and less for the other aspects. Professor Gao Xiyan used acupoints Baliao to treat constipation and diarrhea based on years of clinical experiences. Conclusion: Acupuncturing acupoints Baliao for the treatment of constipation and diarrhea has significant effect with no adverse reactions and could fundamentally improve symptoms.

  10. Gui-ling-gao, a traditional Chinese functional food, prevents oxidative stress-induced apoptosis in H9c2 cardiomyocytes.

    Science.gov (United States)

    Li, Fan; Wu, Jian-Hong; Wang, Qing-Hua; Shu, Yuan-Lan; Wan, Chun-Wai; Chan, Chi-On; Kam-Wah Mok, Daniel; Chan, Shun-Wan

    2013-04-30

    Functional foods have become an increasingly popular alternative to prevent diseases and maintain body health status. Gui-ling-gao (GLG, also known as turtle jelly) is a well-known traditional functional food popular in Southern China and Hong Kong. This study aimed to investigate the antioxidative and anti-apoptotic effects of GLG, a traditional Chinese functional food, on preventing oxidative stress-induced injury in H9c2 cardiomyocytes. In this study, the antioxidative capacities of GLG were measured by using both a cell-free assay [2,2-diphenyl-1-(2,4,6-trinitrophenyl)hydrazyl assay] and biological methods [2,2'-azobis(2-amidinopropane)-induced haemolysis assay and H(2)O(2)-induced cell damage on H9c2 cardiomyocytes]. Additionally, the total phenolic content was measured using the Folin-Ciocalteu method. Furthermore, the anti-apoptotic effect of GLG was evaluated by nuclear staining and a DNA fragmentation assay. GLG was found to have good antioxidant activities and high total phenolic content. In H(2)O(2)-induced cell damage on H9c2 cells, GLG was demonstrated to ameliorate the apoptotic effects, such as nuclear condensations, increased intracellular caspase-3 activity and inter-nucleosomal DNA cleavage, induced by H(2)O(2). The present study demonstrated for the first time that GLG possesses anti-apoptotic potential in vitro and this effect may be mediated, in part, by its antioxidative function. Additionally, the antioxidative capacities of GLG were proved both chemically and biologically. This study provides scientific evidence to prove the anecdotal health-beneficial claim that the consumption of GLG could help the body to handle endogenous toxicants such as free radicals.

  11. On-orbit geometric calibration and geometric quality assessment for the high-resolution geostationary optical satellite GaoFen4

    Science.gov (United States)

    Wang, Mi; Cheng, Yufeng; Chang, Xueli; Jin, Shuying; Zhu, Ying

    2017-03-01

    The Chinese GaoFen4 (GF4) remote sensing satellite, launched at the end of December 2015, is China's first civilian high-resolution geostationary optical satellite and has the world's highest resolution from geostationary orbit. High accuracy geometric calibration is the key factor in the geometrical quality of satellite imagery. This paper proposes an on-orbit geometric calibration approach for the high-resolution geostationary optical satellite GF4 in which a stepwise calibration is performed, external parameters are estimated, and internal parameters are then estimated in a generalized camera frame determined by external parameters. First, the correlation of the imaging error sources and the rigorous imaging model of GF4 are introduced. Second, the geometric calibration model based on the two-dimensional detector directional angle and the parameters estimation method for the planar array camera are presented. LandSat 8 digital orthophoto maps (DOM) and GDEM2 digital elevation models (DEM) are used to validate the efficiency of the proposed method and to make a geometric quality assessment of GF4. The results indicate that changing imaging time and imaging area will dramatically affect the absolute positioning accuracy because of the change of the camera's installation angles caused by thermal environment changes around the satellite in a high orbit. After calibration, the internal distortion is well-compensated, and the positioning accuracy with relatively few ground control points (GCPs) is demonstrated to be better than 1.0 pixels for both the panchromatic and near-infrared sensor and the intermediate infrared sensor.

  12. 高力士人格缺陷形成的心理分析%The Psychological Analysis of Gao Lishi’s Personality Defects and Its Formation

    Institute of Scientific and Technical Information of China (English)

    王瑜

    2015-01-01

    Gao Lishi’s personality had prominent characteristics, namely“cautious and meticulous” and it showed some personality defects. To talk about the reason, on the one hand, he suffered a major blow during the important stage of personality cultivation———the adolescence, such as being confiscated his property, castrated and kicked out of the palace. On the other hand, his workplace is the imperial palace and his service object is the emperor and the concubines; besides, he was threatened many times by the palace coup at the time when he accompanied Xuan Zong to grow up from the captaincy to emperor. All of these made him physically and mentally stressed without the beneficial adjustment and relaxzation, which eventually led to his personality defects.%高力士具有突出的人格特点,即“谨、密”,并表现出一定的人格缺陷。究其原因,一方面是因为他在人格养成的重要阶段———青少年时期———遭遇多次重大打击,如被“藉家”、阉割、逐挞出宫;另一方面是因为他工作的职场是皇宫,服务的对象是皇帝及后宫妃嫔,加之伴随玄宗由藩王到皇帝,一路走来,历经多次宫廷政变的威胁,所有这些使他身心一直处于应激状态,得不到有益的调整和放松,最终导致人格缺陷。

  13. Occupational doses in neuroendocrine tumors by using {sup 177}Lu DOTATATE; Doses ocupacionais em tratamento de tumores neuroendocrinos utilizando {sup 17'}7Lu DOTATATE

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Gustavo Coelho Alves; Sa, Lidia Vasconcellos de, E-mail: gustavo@ird.gov.b, E-mail: lidia@ird.gov.b [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2011-10-26

    This paper investigated the treatment of neuroendocrine tumors (abdominal tumors) using of {sup 177}Lu DOTATATE radiopharmaceutical which is a type of treatment presently used in the experimental form in Brazil and, therefore, not contemplated in norms or specific use. This research studied the occupational doses of this treatment and suggested guidelines or rules of procedures viewing the radiological protection of workers involved and the public. The treatment were followed up by using two types of radiation detection, one a scintillator and a Geiger-Muller, and the measurements were performed in a public hospital at Rio de Janeiro and the other in a private hospital at Sao Paulo. It was observed that the equivalent occupational doses can variate from 160 {mu}Sv to 450 {mu}Sv, in function of operator, of stage of manipulation, and of the administration method, which can be through the use of infusion pump or manual injection. The use of infusion pump is highly recommended and the hospitalization of the patient until the dose rate measured at 1 m does not surpass 20 {mu}Sv/h

  14. Effect of Mg co-doping on cathodoluminescence properties of LuGAGG:Ce single crystalline garnet films

    Science.gov (United States)

    Schauer, P.; Lalinský, O.; Kučera, M.; Lučeničová, Z.; Hanuš, M.

    2017-10-01

    Mg2+ co-doped (LuGd)3(GaAl)5O12:Ce (LuGAGG:Ce,Mg) multicomponent single crystalline epitaxial garnet films were prepared and their cathodoluminescence (CL) and thermoluminescence (TSL) properties were studied in this paper. The films were prepared using the liquid phase epitaxy from lead-free BaO-B2O3-BaF2 flux and their scintillation properties were characterized using the 10 keV collimated e-beam. More specifically, temperature dependent CL intensity, CL emission spectra, CL decay characteristics as well as TSL emission characteristics of the mentioned films were measured. At the highest content of Mg (700 ppm), the CL decay time was as low as 28 ns and the CL afterglow was as low as 0.01% at 1 μs after the e-beam excitation cut-off, which are important parameters for electron detectors in e-beam devices. The CL temperature quenching of the studied films began above room temperature. An increase of Mg concentration to or above 280 ppm quenched the characteristic CL emission of LuGAGG:Ce,Mg. The TSL measurements show that the trap population in studied garnet samples is considerably suppressed. The LuGAGG:Ce,Mg multicomponent single crystalline epitaxial films were evaluated as the perspective fast scintillators for the electron detectors in the e-beam devices.

  15. Effects of thermal treatments on chemical composition and electrical properties of ultra-thin Lu oxide layers on Si

    NARCIS (Netherlands)

    Zenkevich, A.; Lebedinskii, Yu.; Spiga, S.; Wiemer, C.; Scarel, G.; Fanciulli, M.

    2007-01-01

    The correlation between chemical composition, layered structure evolution, and electrical properties of ultra-thin (2-5 nm) Lu oxide layers grown on chemically oxidized Si(100) and exposed to different thermal treatments was monitored by x-ray photoelectron spectroscopy, x-ray reflectivity and C-V,

  16. Siim Nestor soovitab : uute eesti plaatide esitlusõhtud! Metro Luminal. Lu : K. Metsatöll / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2004-01-01

    Rockansambli Metro Luminal plaadi "Reboot" esitlusest Tartu Sadamateatris 9. dets. ja Rock Café's Tallinnas 10. dets.(kaasa teeb DJ Sing). Popansambli Lu:k albumist "Raadiomaja valvelauas" ja ansambli 10. aastapäeva tähistamisest 10. dets. Tallinnas Kunstiakadeemia saalis. Ansambli Metsatöll albumi "Hiiekoda" esitlusest 11.dets. Rock Café's Tallinnas

  17. Archean Lithosphere Beneath Arctic Canada: Lu-Hf Isotope Systematics for Kimberlite-Hosted Garnet-Peridotites From Somerset Island

    Science.gov (United States)

    Schmidberger, S. S.; Simonetti, A.; Francis, D.; Gariepy, C.

    2001-05-01

    Knowledge of the age of lithospheric mantle underlying the continents provides valuable constraints for the timing of formation and stabilization of Archean cratons. This study reports Lu-Hf isotopic data for garnet-peridotites, and their constituent garnets, from the Nikos kimberlite (100 Ma) on Somerset Island in the Canadian Arctic obtained using a Micromass IsoProbe multicollector inductively coupled plasma mass spectrometer (MC-ICP-MS) at GEOTOP-UQAM. The low temperature peridotites (1100 C; 160-190 km) and their 176Hf/177Hf(0.1Ga) isotopic compositions (0.28265-0.28333; \\epsilonHf(0.1Ga)=-2 to +22) are less radiogenic than those of the shallow xenoliths. A Lu-Hf isochron for six peridotites yields a mid Archean age of 3.4\\pm0.3 Ga and an initial 176Hf/177Hf ratio of 0.28101\\pm24. The remaining peridotites (n=9), in contrast, are characterized by extremely high (+35) initial \\epsilonHf(3.4Ga) values, which correlate negatively with their 176Lu/177Hf ratios, suggesting addition of Hf as a result of metasomatic interaction with the host kimberlite. The garnets from the low temperature (3.4 Ga old) peridotites are characterized by high 176Lu/177Hf ratios and define an errorchron age of 1.4\\pm0.2 Ga, which may reflect re-equilibration of Hf during kimberlite magmatism.

  18. In-band pumping of expitaxially grown $Er:(Gd, Lu)_2O_3$ waveguides for active integrated optical devices

    NARCIS (Netherlands)

    Kahn, A.; Kühn, H.; Heinrich, S.; Gün, T.; Tellkamp, F.; Petermann, K.; Bradley, J.D.B.; Ay, F.; Wörhoff, K.; Pollnau, M.; Kuzminykh, Y.; Luo, Y.; Hoffmann, P.; Huber, G.

    2008-01-01

    Monocrystalline lattice matched Er(0.6%):(Gd, Lu)2O3 films with thicknesses up to 3 m and nearly atomically flat surfaces have been deposited on Y2O3 substrates by Pulsed Laser Deposition (PLD). The epitaxial growth has been verified in-situ by Reflection High Energy Electron Diffraction (RHEED). A

  19. Pairs of charged heavy fermions from an $SU(3)_{L}(-)U(1)_{N}$ model at $e^{+}e^{-}$ colliders

    CERN Document Server

    Cieza-Montalvo, J E; 10.1103/PhysRevD.67.075022

    2003-01-01

    We investigate the production, backgrounds, and signatures of pairs of charged heavy fermions using the SU(3)/sub L/(-)U(1)/sub N/ electroweak model in e/sup +/e/sup -/ colliders (Next Linear Collider and CERN Linear Collider). We also analyze the indirect evidence for a boson Z'. (23 refs).

  20. A density functional investigation on the electronic and magnetic properties of LnSi (Ln= La-Lu) Diatom

    Indian Academy of Sciences (India)

    Zhao Run-Ning; Chen Rui; Yuan Yan-Hong; Gu Fan; Han Ju-Guang

    2016-03-01

    Bond lengths, vibrational frequencies, electron affinities, magnetic properties, and ionization potentials of the neutral and charged LnSi (Ln=La-Lu) diatom were studied by using the density functional method with relativistic effect being taken into account. Ground state was assigned for each species. The calculated natural populations of LnSi (Ln=La-Lu) exhibit that the charges are transferred mainly from 6s2 to 5d,and most of 4f subshell in LnSi is inert without involving chemical bonding. The calculated highest occupied molecular orbital-lowest unoccupied molecular orbital (HOMO-LUMO) gaps show that the HOMO-LUMOgaps are increased and exhibit oscillating behavior from LaSi to LuSi.Interestingly, total magnetic properties of LnSi (Ln=La-Lu)diatoms depend on the localized 4f electrons which generate the magnetic moment of LnSi diatoms; additionally, the magnetic moment of EuSi is 11 μB, which is the highest one. Comparisons with the available experimental and theoretical values are made and a good agreement is reached.

  1. Comparison of ⁹⁰Y and ¹⁷⁷Lu measurement capability in UK and European hospitals.

    Science.gov (United States)

    Fenwick, Andrew; Baker, Michaela; Ferreira, Kelley; Keightley, John

    2014-05-01

    Comparison exercises involving (90)Y and (177)Lu were performed during 2009 and 2012, respectively, to assess the measurement capability of hospitals in the UK and Europe. The results from the measurement of a typical liquid solution of (90)Y show that only 40% of participants could measure the solution to within 5% of the certificated value and that a significant -6% bias was present due to the use of non-standard geometries for the calibration of equipment. The results from the measurement of a standard liquid solution of (177)Lu show that 81% of participants could measure to within 5% of the certificated value and in fact 65% of these results were within 2% of the certificated value, showing administered activities can be far more accurately measured for (177)Lu than for (90)Y and that (177)Lu has a far smaller geometry dependence. These studies were performed to identify specific measurement issues in the user community and to identify areas where future research should be focused. In addition to this the work allows the participants to adjust measurement practice and identify key measurement issues.

  2. 鲁迅对自己杂文的两种态度%Lu Xun's Ambivalent Attitudes Towards His Essay

    Institute of Scientific and Technical Information of China (English)

    陈正敏

    2015-01-01

    通过具体材料的梳理,揭示了鲁迅杂对自己杂文的两种态度:在公开发表的文字中,鲁迅对自己的杂文极为自信,甚至自负;但在私人场合——与友人的通信里,则不断地表示对自己杂文的不满,认为自己的杂文写作只是无意义的"打杂",并非真正的创作.与此同时,鲁迅常常表示小说才是真正的创作,他很想专心于这项工作,却已无力去做.%By combing concrete materials, the author finds a noticeable phenomenon from Lu Xu's essay writing. This paper puts forward some new views on Lu Xun's essays: although Lu Xun exhibited strong confidence in his public published articles, he expressed dissatisfaction with his essays constantly in private occasions, i.e. in the letters to his friends. And he said his essay writing was something worthless rather than literary creation. At the same time, Lu Xun always hinted that the writing of fiction was real literary creation, and he wanted to concentrate on fiction writing, but he was unable to do this.

  3. Lattice dynamics of xenotime: The phonon dispersion relations and density of states of LuPO{sub 4}

    Energy Technology Data Exchange (ETDEWEB)

    Nipko, J.C.; Loong, C. [Argonne National Laboratory, Argonne, Illinois 60439-4814 (United States); Loewenhaupt, M. [Technische Universitaet Dresden, Dresden (Germany); Braden, M.; Reichardt, W. [Forschungszentrum Karlsruhe, INFP, D-76021, Karlsruhe (Germany); Boatner, L.A. [Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6056 (United States)

    1997-11-01

    LuPO{sub 4} is the nonmagnetic end member of a series of rare-earth phosphates with a common zircon-type crystal structure. The phonon-dispersion curves of LuPO{sub 4} along the [x,0,0], [x,x,0], and [0,0,x] symmetry directions were measured by neutron triple-axis spectroscopy using single-crystal samples. The phonon density of states was determined by time-of-flight neutron scattering using polycrystalline samples. Phonons involving mainly motions of rare-earth ions were found to be well separated in energy from those of the P and O vibrations. A large gap in the phonon-frequency-distribution function, which divides the O-P-O bending-type motions from the P-O stretches, was observed. All of the experimental results were satisfactorily accounted for by lattice-dynamic shell-model calculations. LuPO{sub 4} is a host material for the incorporation of rare-earth ions to produce activated luminescence. Information regarding the phonon and thermodynamic properties of LuPO{sub 4} is pertinent to extended investigations of additional rare-earth spin-lattice interactions in other zircon-structure rare-earth orthophosphates. {copyright} {ital 1997} {ital The American Physical Society}

  4. Siim Nestor soovitab : uute eesti plaatide esitlusõhtud! Metro Luminal. Lu : K. Metsatöll / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2004-01-01

    Rockansambli Metro Luminal plaadi "Reboot" esitlusest Tartu Sadamateatris 9. dets. ja Rock Café's Tallinnas 10. dets.(kaasa teeb DJ Sing). Popansambli Lu:k albumist "Raadiomaja valvelauas" ja ansambli 10. aastapäeva tähistamisest 10. dets. Tallinnas Kunstiakadeemia saalis. Ansambli Metsatöll albumi "Hiiekoda" esitlusest 11.dets. Rock Café's Tallinnas

  5. Crystal Structure and Thermal Expansion Properties of Lu_(2-x)Fe_xMo_3O_(12)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Low or zero thermal expansion materials have a lot of potential applications in space shuttle, microelectronic components, and optical mirrors et al. Polycrystalline samples Lu2-xFexMo3O12 have been prepared successfully by solid state reaction,

  6. Effect of Lu2O3 on Charge/discharge Performances of Spherical Nickel Hydroxide at High Temperature

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Nickel-metal hydride (Ni/MH) batteries are one of promising batteries for electric vehicle applications, but at high temperature the charge efficiency of nickel electrode is very low. In order to improve the high-temperature-efficiency of nickel electrode, spherical nickel hydroxide mixed with various ratios of Lu2O3 was used as active material of pasted nickel electrodes. The results of charge/discharge experiments, cyclic voltammetric measurements and XRD characterizations have shown that after addition of Lu2O3, the oxygen evolution overpotential is elevated much, the charge efficiency of nickel electrode at high temperature is greatly improved and the content of β-NiOOH phase increases in charged electrodes. In addition, the mixed ratio of Lu2O3 has different effects on high temperature performances of nickel electrode at different charge/discharge currents, 3.5 % is the optimum mixed ratio, and the action of Lu2O3 on high temperature electrochemical behaviors is more apparent when nickel electrodes are charged at small current than large current.

  7. Relativistic many-body calculation of energies, lifetimes, polarizabilities, blackbody radiative shift, and hyperfine constants in Lu2 +

    Science.gov (United States)

    Safronova, U. I.; Safronova, M. S.; Johnson, W. R.

    2016-09-01

    Energy levels of 30 low-lying states of Lu2 + and allowed electric-dipole matrix elements between these states are evaluated using a relativistic all-order method in which all single, double, and partial triple excitations of Dirac-Fock wave functions are included to all orders of perturbation theory. Matrix elements are critically evaluated for their accuracy and recommended values of the matrix elements are given together with uncertainty estimates. Line strengths, transition rates, and lifetimes of the metastable 5 d3 /2 and 5 d5 /2 states are calculated. Recommended values are given for static polarizabilities of the 6 s , 5 d , and 6 p states and tensor polarizabilities of the 5 d and 6 p3 /2 states. Uncertainties of the polarizability values are estimated in all cases. The blackbody radiation shift of the 6 s1 /2-5 d5 /2 transition frequency of the Lu2 + ion is calculated with the aid of the recommended scalar polarizabilities of the 6 s1 /2 and 5 d5 /2 states. Finally, A and B hyperfine constants are determined for states of 2+175Lu with n ≤9 . This work provides recommended values of transition matrix elements, polarizabilities, and hyperfine constants of Lu2 +, critically evaluated for accuracy, for benchmark tests of high-precision theoretical methodology and planning of future experiments.

  8. Gamma induced atom displacements in LYSO and LuYAP crystals as used in medical imaging applications

    Energy Technology Data Exchange (ETDEWEB)

    Piñera, Ibrahin, E-mail: ipinera@ceaden.edu.cu [Centro de Aplicaciones Tecnológicas y Desarrollo Nuclear, CEADEN, 30 St. 502, Playa 11300, Havana (Cuba); Cruz, Carlos M.; Abreu, Yamiel; Leyva, Antonio [Centro de Aplicaciones Tecnológicas y Desarrollo Nuclear, CEADEN, 30 St. 502, Playa 11300, Havana (Cuba); Van Espen, Piet [University of Antwerp, CGB, Groenenborgerlaan 171, 2020 Antwerpen (Belgium); Díaz, Angelina; Cabal, Ana E. [Centro de Aplicaciones Tecnológicas y Desarrollo Nuclear, CEADEN, 30 St. 502, Playa 11300, Havana (Cuba); Van Remortel, Nick [University of Antwerp, CGB, Groenenborgerlaan 171, 2020 Antwerpen (Belgium)

    2015-08-01

    The radiation damage, in terms of atom displacements, induced by gamma irradiation in LYSO and LuYAP crystals is presented. {sup 44}Sc, {sup 22}Na and {sup 48}V are used as gamma sources for this study. The energy of gammas from the electron–positron annihilation processes (511 keV) is also included in the study. The atom displacements distributions inside each material are calculated following the Monte Carlo assisted Classical Method introduced by the authors. This procedure also allows to study the atom displacements in-depth distributions inside each crystal. The atom displacements damage in LYSO crystals is found to be higher than in LuYAP crystals, mainly provoked by the displacements of silicon and oxygen atoms. But the difference between atom displacements produced in LYSO and LuYAP decreases when more energetic sources are used. On the other hand, the correlation between the atom displacements and energy deposition in-depth distributions is excellent. The atom displacements to energy deposition ratio is found to increases with more energetic photon sources. LYSO crystals are then more liable to the atom displacements damage than LuYAP crystals.

  9. Hypocalcaemia after treatment with [{sup 177}Lu-DOTA{sup 0},Tyr{sup 3}]octreotate

    Energy Technology Data Exchange (ETDEWEB)

    Vliet, Esther I. van; Kam, Boen L.R.; Teunissen, Jaap J.M.; Krenning, Eric P.; Kwekkeboom, Dik J. [Erasmus MC, University Medical Center, Department of Nuclear Medicine, Rotterdam (Netherlands); Herder, Wouter W. de; Zillikens, M.C.; Peeters, Robin P. [Erasmus MC, University Medical Center, Department of Internal Medicine, Rotterdam (Netherlands); Rijke, Yolanda B. de [Erasmus MC, University Medical Center, Department of Clinical Chemistry, Rotterdam (Netherlands)

    2013-12-15

    The aim of this study was to explore the possible mechanisms involved in an observed decline in serum calcium levels in patients with a neuroendocrine tumour (NET) treated with [{sup 177}Lu-DOTA{sup 0},Tyr{sup 3}]octreotate ({sup 177}Lu-octreotate). In 47 patients with NET who were normocalcaemic at baseline, serum calcium, albumin, creatinine, alkaline phosphatase, gamma glutamyl transpeptidase, magnesium, phosphate and 25-hydroxyvitamin D were prospectively analysed at baseline and up to 6 months after treatment. Parathyroid hormone (PTH), 1,25-dihydroxyvitamin D{sub 3}, type 1 aminoterminal propeptide of procollagen, bone-specific alkaline phosphatase, carboxyterminal crosslinking telopeptide of bone collagen, collagen type I crosslinked N-telopeptide, and creatinine and calcium in 24-h urine samples, were evaluated at baseline and at 3 and 6 months. Another 153 patients with NET were included in a retrospective study to estimate the occurrence of hypocalcaemia in a larger patient group. In the prospectively included patients, the mean serum calcium level decreased significantly after treatment (2.31 {+-} 0.01 to 2.26 {+-} 0.02 mmol/l, p = 0.02). Eight patients (17 %) showed a marked decrease in serum calcium levels with a nadir of {<=}2.10 mmol/l. In five patients (11 %), calcium substitution therapy was prescribed. PTH increased significantly (5.9 {+-} 0.6 to 6.7 {+-} 0.8 pmol/l, p = 0.02), presumably in response to the decreasing serum calcium levels. 25-Hydroxyvitamin D remained stable after treatment. Creatinine levels increased significantly (73 {+-} 3 to 77 {+-} 3 {mu}mol/l, p = 0.01), but not enough to explain the hypocalcaemia. Phosphate levels remained unaffected. In the retrospectively analysed patients, the mean serum calcium level decreased significantly from 2.33 {+-} 0.01 at baseline to a nadir of 2.24 {+-} 0.01 mmol/l at 18 months after treatment (p < 0.001). Of the 153 patients, 33 (22 %) showed a serum calcium nadir of {<=}2.10 mmol/l, and 11

  10. Potential Biomarkers for Radiation-Induced Renal Toxicity following 177Lu-Octreotate Administration in Mice.

    Directory of Open Access Journals (Sweden)

    Emil Schüler

    Full Text Available The kidneys are one of the main dose-limiting organs in peptide receptor radionuclide therapy and due to large inter-individual variations in renal toxicity, biomarkers are urgently needed in order to optimize therapy and reduce renal tissue damage. The aim of this study was to investigate the transcriptional, functional, and morphological effects on renal tissue after 177Lu-octreotate administration in normal mice, and to identify biomarkers for radiation induced renal toxicity.C57BL/6N mice were i.v. injected with 0, 30, 60, 90, 120, or 150 MBq 177Lu-octreotate (0, 16, 29, 40, 48, and 54 Gy to the kidneys. At 4, 8, and 12 months after administration, radiation-induced effects were evaluated in relation to (a global transcriptional variations in kidney tissues, (b morphological changes in the kidneys, (c changes in white and red blood cell count as well as blood levels of urea, and (d changes in renal function using 99mTc-DTPA/99mTc-DMSA scintigraphy.In general, the highest number of differentially regulated transcripts was observed at 12 months after administration. The Cdkn1a, C3, Dbp, Lcn2, and Per2 genes displayed a distinct dose-dependent regulation, with increased expression level with increasing absorbed dose. Ifng, Tnf, and Il1B were identified as primary up-stream regulators of the recurrently regulated transcripts. Furthermore, previously proposed biomarkers for kidney injury and radiation damage were also observed. The functional investigation revealed reduced excretion of 99mTc-DTPA after 150 MBq, an increased uptake of 99mTc-DMSA at all dose levels compared with the controls, and markedly increased urea level in blood after 150 MBq at 12 months.Distinct dose-response relationships were found for several of the regulated transcripts. The Cdkn1a, Dbp, Lcn2, and Per2 genes are proposed as biomarkers for 177Lu-octreotate exposure of kidney. Correlations to functional and morphological effects further confirm applicability of these

  11. Anti-EGFRvIII monoclonal antibody armed with {sup 177}Lu: in vivo comparison of macrocyclic and acyclic ligands

    Energy Technology Data Exchange (ETDEWEB)

    Hens, Marc; Vaidyanathan, Ganesan; Zhao Xiaoguang [Department of Radiology, Duke University Medical Center, Durham, NC 27710 (United States); Bigner, Darell D. [Department of Pathology, Duke University Medical Center, Durham, NC 27710 (United States); Zalutsky, Michael R., E-mail: zalut001@mc.duke.ed [Department of Radiology, Duke University Medical Center, Durham, NC 27710 (United States)

    2010-10-15

    Introduction: Monoclonal antibody (mAb) L8A4 binds specifically to the epidermal growth factor receptor variant III (EGFRvIII) that is present on gliomas but not on normal tissues, and is internalized rapidly after receptor binding. Because of the short range of its {beta}-emissions, labeling this mAb with {sup 177}Lu would be an attractive approach for the treatment of residual tumor margins remaining after surgical debulking of brain tumors. Materials and Methods: L8A4 mAb was labeled with {sup 177}Lu using the acyclic ligands [(R)-2-amino-3-(4-isothiocyanatophenyl)propyl]-trans-(S,S)-cyclohexane-1, 2-diamine-pentaacetic acid (CHX-A''-DTPA) and 2-(4-isothiocyanatobenzyl)-6-methyldiethylene-triaminepentaacetic acid (1B4M-DTPA), and the macrocyclic ligands S-2-(4-isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane-tetraacetic acid (C-DOTA) and {alpha}-(5-isothiocyanato-2-methoxyphenyl)-1,4,7,10-tetraazacyclododecane-1,4,7, 10-tetraacetic acid (MeO-DOTA). Paired-label tissue distribution experiments were performed in athymic mice bearing subcutaneous EGFRvIII-expressing U87.{Delta}EGFR glioma xenografts over a period of 1 to 8 days to directly compare {sup 177}Lu-labeled L8A4 to L8A4 labeled with {sup 125}I using N-succinimidyl 4-guanidinomethyl-3-[{sup 125}I]iodobenzoate ([{sup 125}I]SGMIB). Results: Except with C-DOTA, tumor uptake for the {sup 177}Lu-labeled mAb was significantly higher than the co-administered radioiodinated preparation; however, this was also the case for spleen, liver, bone and kidneys. Tumor/normal tissue ratios for {sup 177}Lu-1B4M-DTPA-L8A4 and, to an even greater extent, {sup 177}Lu-MeO-DOTA-L8A4 were higher than those for [{sup 125}I]SGMIB-L8A4 in most other tissues. Conclusions: Tumor and normal tissue distribution patterns for this anti-EGFRvIII mAb were dependent on the nature of the bifunctional chelate used for {sup 177}Lu labeling. Optimal results were obtained with 1B4M-DTPA and MeO-DOTA, suggesting no clear advantage

  12. Clinical observation on treating 40 cases of infantile anorexia with Xiaodao Gao%消导膏穴位贴敷治疗小儿厌食症40例疗效观察

    Institute of Scientific and Technical Information of China (English)

    刘丽平

    2014-01-01

    Objective:To observe clinical effects of Xiaodao Gao on treating infantile anorexia. Methods:80 patients were divided into the treatment given Xiaodao Gao and the control received Xingpi Yanger granule, children appetite and intakeing in two groups were observed after 1 course treatment. Results:The total efficacy in the treatment was 95.0%, higher than 75.0%in the control, the difference was statistically significant (P<0.05). Effects in the treatment were better. Conclusion: Xiaodao Gao achieved good effects with easy compliance and was worthy of promotion.%目的:观察消导膏穴位贴敷治疗小儿厌食症的临床疗效。方法:将80例小儿厌食症患儿按就诊先后顺序随机分为治疗组40例与对照组40例,治疗组予消导膏穴位贴敷,对照组予醒脾养儿颗粒口服,10d为1疗程。1个疗程后观察患儿食欲、食量的变化。结果:1个疗程后治疗组总有效率95.0%,高于对照组75.0%,差异有统计学意义(P<0.05)。治疗组疗效优于对照组。结论:消导膏穴位贴敷治疗小儿厌食症有良好疗效,患儿依从性高,值得临床推广。

  13. 东方文化视野中的鲁迅与泰戈尔--“鲁迅与泰戈尔:跨时空对话”笔谈%Lu Xun and Tagore from the Perspective of Oriental Culture---Lu Xun and Tagore:“a Dialogue Across Time and Space”

    Institute of Scientific and Technical Information of China (English)

    叶飞帆

    2016-01-01

    Tagore, a renowned writer in India, is the first Asian to win the Nobel Prize for Literature. Lu Xun, the greatest writer in modern China, is known as the “national soul” in modern China. Deeply rooted in the soil of oriental culture, both Lu Xun and Tagore board the peak of the eastern literature and exert a great impact on the world literature. With the two literary giants of the oriental nations, Lu Xun and Tagore not only have extensive and profound influence on the readers of China and India, but are a symbol of the cultural exchanges between China and India as well. In 1924, Tagore visited China, which sparkled the Tagore Fever. Lu Xun attended Tagore’s sixty-fourth birthday celebration and watched the English drama Zidla. It was the great occasion when the two cultural giants from different countries met one another for the first time. Since then, Lu Xun has repeatedly talked about Tagore. According to incomplete statistics, Lu Xun mentioned Tagore in his articles for at least 14 times, demonstrating the fact that the great minds admired one another. Sponsored by Lu Xun Cultural Founda-tion, the international academic forum“Lu Xun and Tagore:a Dialogue Across Time and Space” was ceremoni-ously held in Shaoxing University on June 14, 2016. The descendants of the two colossi, together with literature experts from China and India, assembled at Shaoxing University in the hometown of Lu Xun. It is to resume the dialogue not yet made between Tagore and Lu Xun when they met in their lifetime. I believe that the “dialogue between masters” enables us to further understand not only the similarities between Lu Xun and Tagore’ s minds but also the contemporary value of their cultural heritage. Meanwhile, the “dialogues” have helped carry over the two eminent writers’ cultural exchanges up till now, and will further deepen Sino-Indian literary and cultural exchanges.

  14. Preparation and bioevaluation of {sup 177}Lu-labelled anti-CD44 for radioimmunotherapy of colon cancer

    Energy Technology Data Exchange (ETDEWEB)

    Lee, So Young; Hong, Young Don; Jung, Sung Hee; Choi, Sun Ju [Radioisotope Research Division, Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-12-15

    CD44 is a particular adhesion molecule and facilitates both cell-cell and cell-matrix interactions. In particular, splice variants of CD44 are particularly overexpressed in a large number of malignancies and carcinomas. In this study, the {sup 177}Lu-labelled CD44 targeting antibody was prepared and bioevaluated in vitro and in vivo. Anti-CD44 was immunoconjugated with the equivalent molar ratio of cysteine-based dtPA-ncS and radioimmunoconjugated with {sup 177}Lu at room temperature within 15 minutes. the stability was tested in human serum. An in vitro study was carried out in Ht-29 human colon cancer cell lines. For the biodistribution study {sup 177}Lu-labelled anti-CD44 was injected in xenograft mice. Anti-CD44 was immunoconjugated with cysteinebased dtPA-ncS and purified by a centricon filter system having a molecular cut-off of 50 kda. radioimmunoconjugation with {sup 177}Lu was reacted for 15 min at room temperature. the radiolabeling yield was >99%, and it was stable in human serum without any fragmentation or degradation. The radioimmunoconjugate showed a high binding affinity on HT-29 colon cancer cell surfaces. In a biodistribution study, the tumor-to-blood ratio of the radioimmunoconjugate was 43 : 1 at 1 day post injection (p.i) in human colon cancer bearing mice. the anti-CD44 monoclonal antibody for the targeting of colon cancer was effectively radioimmunoconjugated with {sup 177}Lu. the in vitro high immunoactivity of this radioimmunoconjugate was determined by a cell binding assay. In addition, the antibody's tumor targeting ability was demonstrated with very high uptake in tumors. this radioimmunoconjugate is applicable to therapy in human colon cancer with highly expressed CD44.

  15. 水热法制备的LuFeO3晶粒的超声催化活性%Sonocatalytic activity of LuFeO3 crystallites synthesized via a hydrothermal route

    Institute of Scientific and Technical Information of China (English)

    周明; 杨华; 县涛; 杨阳; 张云川

    2015-01-01

    LuFeO3 crystallites of different sizes and morphologies were synthesized via a hydrothermal route. The sonocatalytic properties of the as‐synthesized samples were investigated by degrading various organic dyes, including acid orange 7 (AO7), rhodamine B (RhB), methyl orange (MO), and meth‐ylene blue (MB), under ultrasonic irradiation, revealing that they exhibit excellent sonocatalytic activity toward the degradation of these dyes. Particularly, the synthesized bar‐like particles with lengths of~3μm and widths of~1μm have the highest sonocatalytic activity, and the degradation percentage of AO7 reaches 89%after 30 min of sonocatalysis. The effects of inorganic anions such as Cl−, NO3−, SO42−, PO43−, and HCO3− on the sonocatalysis efficiency were investigated. Hydroxyl radicals (•OH) detected by fluorimetry using terephthalic acid as a probe molecule were found to be produced over the ultrasonic‐irradiated LuFeO3 particles. The addition of ethanol, which acts as a•OH scavenger, leads to quenching of •OH radicals and a simultaneous decrease in the dye degrada‐tion. This suggests that•OH is the dominant active species responsible for the dye degradation.%超声波在水中传播时会产生大量空化气泡,空化气泡经历成核、生长和瞬间崩塌等过程,并在崩塌瞬间产生局部高温和高压,过程中会发出瞬间闪光,即声致发光.局部高温高压及声致发光可将半导体价带上的电子激发至导带,形成电子/空穴对,电子和空穴迁移至半导体颗粒表面,参与一系列氧化还原反应致使有机污染物发生分解.由于超声波在各种液体中都具有很强的穿透能力,因此与半导体光催化技术相比,半导体超声催化技术在降解高浓度和不透明染料废水时具有明显优势. LuFeO3是稀土正铁氧体中的一员,具有独特磁结构、巨介电常数及多铁性,近年来引起了人们极大的研究兴趣.同时, LuFeO3也是一种窄带隙半

  16. Hormonal crises following receptor radionuclide therapy with the radiolabeled somatostatin analogue [{sup 177}Lu-DOTA{sup 0},Tyr{sup 3}]octreotate

    Energy Technology Data Exchange (ETDEWEB)

    Keizer, Bart de; Kam, Boen L.R.; Essen, Martijn van; Krenning, Eric P.; Kwekkeboom, Dik J. [Erasmus Medical Center, Department of Nuclear Medicine, Rotterdam, P.O. Box 2040 (Netherlands); Aken, Maarten O. van; Feelders, Richard A.; Herder, Wouter W. de [Erasmus Medical Center, Section of Endocrinology, Department of Internal Medicine, Rotterdam (Netherlands)

    2008-04-15

    Receptor radionuclide therapy is a promising treatment modality for patients with neuroendocrine tumors for whom alternative treatments are limited. The aim of this study was to investigate the incidence of hormonal crises after therapy with the radiolabeled somatostatin analogue [{sup 177}Lu-DOTA{sup 0},Tyr{sup 3}]octreotate ({sup 177}Lu-octreotate). All {sup 177}Lu-octreotate treatments between January 2000 and January 2007 were investigated. Four hundred seventy-six patients with gastroenteropancreatic neuroendocrine tumors and three patients with metastatic pheochromocytoma were included for analysis. Four hundred seventy-nine patients received a total of 1,693 administrations of {sup 177}Lu-octreotate. Six of 479 patients (1%) developed severe symptoms because of massive release of bioactive substances after the first cycle of {sup 177}Lu-octreotate. One patient had a metastatic hormone-producing small intestinal carcinoid; two patients had metastatic, hormone-producing bronchial carcinoids; two patients had vasoactive intestinal polypeptide-producing pancreatic endocrine tumors (VIPomas); and one patient had a metastatic pheochromocytoma. With adequate treatment, all patients eventually recovered. Hormonal crises after {sup 177}Lu-octreotate therapy occur in 1% of patients. Generally, {sup 177}Lu-octreotate therapy is well tolerated. (orig.)

  17. Diode-side-pumped, passively Q-switched Yb:LuAG laser

    Science.gov (United States)

    Kaskow, Mateusz; Galecki, Lukasz; Jabczynski, Jan K.; Skorczakowski, Marek; Zendzian, Waldemar; Sulc, Jan; Nemec, Michal; Jelinkova, Helena

    2015-10-01

    A high-gain, diode-side-pumped Yb:LuAG slab laser was designed and investigated for use at room temperature. Pumping occurred from a fast-axis collimated 2D laser diode stack emitting at a wavelength of 970 nm, with 0.8 J over a duration of 0.8 ms. The pump scheme, which enabled efficient mode matching and high gain, was analysed and experimentally verified for different dopant levels. An energy of 100 mJ with 23% slope efficiency in a near fundamental mode was achieved in the free-running regime. A peak power of 2.5 MW and a pulse energy of 10.1 mJ were demonstrated in passive Q-switching by means of a Cr:YAG saturable absorber with 39% initial transmission. The study defined the indications for optimizing such a system.

  18. Improving quantitative dosimetry in (177)Lu-DOTATATE SPECT by energy window-based scatter corrections

    DEFF Research Database (Denmark)

    de Nijs, Robin; Lagerburg, Vera; Klausen, Thomas L

    2014-01-01

    and the activity, which depends on the collimator type, the utilized energy windows and the applied scatter correction techniques. In this study, energy window subtraction-based scatter correction methods are compared experimentally and quantitatively. MATERIALS AND METHODS: (177)Lu SPECT images of a phantom...... with known activity concentration ratio between the uniform background and filled hollow spheres were acquired for three different collimators: low-energy high resolution (LEHR), low-energy general purpose (LEGP) and medium-energy general purpose (MEGP). Counts were collected in several energy windows......, and scatter correction was performed by applying different methods such as effective scatter source estimation (ESSE), triple-energy and dual-energy window, double-photopeak window and downscatter correction. The intensity ratio between the spheres and the background was measured and corrected for the partial...

  19. Design and Implementation of the ScaLAPACK LU, QR, and Cholesky Factorization Routines

    Directory of Open Access Journals (Sweden)

    Jaeyoung Choi

    1996-01-01

    Full Text Available This article discusses the core factorization routines included in the ScaLAPACK library. These routines allow the factorization and solution of a dense system of linear equations via LU, QR, and Cholesky. They are implemented using a block cyclic data distribution, and are built using de facto standard kernels for matrix and vector operations (BLAS and its parallel counterpart PBLAS and message passing communication (BLACS. In implementing the ScaLAPACK routines, a major objective was to parallelize the corresponding sequential LAPACK using the BLAS, BLACS, and PBLAS as building blocks, leading to straightforward parallel implementations without a significant loss in performance. We present the details of the implementation of the ScaLAPACK factorization routines, as well as performance and scalability results on the Intel iPSC/860, Intel Touchstone Delta, and Intel Paragon System.

  20. Grain size effect on magnetic and electric properties of LuMnO3 nanocrystalline materials

    Science.gov (United States)

    Han, Tai-Chun; Chen, Jia-Wern; Liu, Yuan-Hsun; Hu, Yu-Min

    2013-05-01

    Magnetic and electric properties are investigated for the nanosized LuMnO3 samples with different grain sizes (30 nm to 500 nm) synthesized by a modified Pechini method. It shows that magnetic and electric properties are strongly dependent on the grain size. The magnetic characterization indicates that with increasing grain size, the antiferromagnetic (AFM) transition temperature increases from 72 to 89 K. The temperature-dependent dielectric measurements show an anomaly in the dielectric constant at temperatures close to the AFM ordering temperature for all samples. A corresponding shift of the peak-positions of dielectric anomaly and magnetic ordering indicates a strong correlation between the magnetic ordering and the electric polarization. Further analysis suggests that the rising of AFM transition temperature with increasing grain size should be from the structural origin, in which the strength of AFM interaction as well as the electrical polarization is dependent on the in-plane lattice parameters.

  1. Anomalous Phonon Behavior in Orthorhombic LuMnO3 at Low Temperature

    Science.gov (United States)

    Gao, Peng; Chen, Haiyan; Tyson, Trevor A.; Liu, Zhenxian; Bai, Jianming; Wang, Liping; Choi, Youngjai; Cheong, Sang-Wook

    2011-03-01

    We present the pressure dependent phonon spectra of orthorhombic-LuMnO3 which are conducted in the low temperature region (below TN and TL) . A temperature dependent anomalous phonon coincides with the ferroelectric behavior at low pressure condition. At ~ 10 GPa, this anomalous phonon exhibits an unusual softening trend which will be suppressed at higher pressure. This work is supported by DOE Grant DE-FG02-07ER46402 (NJIT), by DE-FG02-07ER46402 (Rutgers), by COMPRES (U2A beam line at NSLS), the Consortium for Materials Properties Research in Earth Sciences under NSF Cooperative Agreement EAR01-35554, U.S. Department of Energy (DOE-BES and NNSA/CDAC) and by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences, under Contract No. DE-AC02-98CH10886 (use of NSLS at Brookhaven National Laboratory).

  2. Composition and species evolution in a laser-induced LuMnO3 plasma

    Science.gov (United States)

    Bator, Matthias; Hu, Yi; Esposito, Martin; Schneider, Christof W.; Lippert, Thomas; Wokaun, Alexander

    2012-09-01

    Pulsed laser deposition is often used to grow multi-elemental thin films from stoichiometric targets. The growth process is influenced by a wide variety of parameters like the target composition, background gases, laser wavelength, laser fluence, or spot size. The changes these parameters induce in the film growth also affect the plasma plume and species formed during laser ablation. For oxide growth O2, and sometimes N2O, is utilized as background gas to achieve the required oxygen composition for the as-grown film. Mass spectrometry combined with time- and space resolved emission spectroscopy is used to investigate the behavior and evolution of plasma species in the plasma plume during the ablation process of LuMnO3 dependent on the background gas.

  3. Exchange Interaction Effects on the Optical Properties of LuMnO3

    Science.gov (United States)

    Souchkov, A. B.; Simpson, J. R.; Quijada, M.; Ishibashi, H.; Hur, N.; Ahn, J. S.; Cheong, S. W.; Millis, A. J.; Drew, H. D.

    2003-07-01

    We have measured the optical conductivity of single crystal LuMnO3 from 10 to 45 000 cm-1 at temperatures between 4 and 300K. A symmetry allowed on-site Mn d-d transition near 1.7eV is observed to blueshift (˜0.1 eV) in the antiferromagnetic state due to Mn Mn superexchange interactions. Similar anomalies are observed in the temperature dependence of the TO phonon frequencies which arise from spin-phonon interaction. We find that the known anomaly in the temperature dependence of the quasistatic dielectric constant ɛ0 below TN˜90 K is overwhelmingly dominated by the phonon contributions.

  4. Oxygen displacements and magnetoelectric coupling in LuMnO3

    Science.gov (United States)

    Tong, P.; Louca, Despina; Lee, Nara; Cheong, S.-W.

    2012-09-01

    The hexagonal multiferroic LuMnO3 transforms to the P63cm symmetry upon entering the ferroelectric phase. Using neutron diffraction and the pair density function analysis, it is shown that short-range local atomic distortions are present, calling for a lower symmetry, such as the P63, for the following reasons. With cooling, the MnO5 bipyramid tilting becomes more enhanced than previously determined. This splits the in-plane Mn-O-Mn angles especially below TN, leading to inequivalent magnetic coupling constants J between the in-plane Mn ions. Additionally, below TN, several weak incommensurate magnetic phases appear in response to the reminiscent frustration from the triangular Mn lattice. The complex magnetic structure may be the driving mechanism for the lower crystal symmetry.

  5. Femtosecond Spectroscopy of Electron-Lattice Coupling in LuMnO3

    Science.gov (United States)

    Lou, Shitao

    2005-03-01

    Hexagonal manganite LuMnO3 is a ferroelectric (Tc 900 K) and strongly frustrated antiferromagnetic (TN 90 K) crystal. Strong coupling between lattice, electronic, and magnetic degrees of freedom make it a promissing electronic material. We have used femtosecond pump-probe spectroscopy to observe the interaction of electron excitation and lattice vibration in real time. Optical excitation at a sharp absorption peak at 800 nm corresponding to a Mn d(x^2-y^2),(xy)->d(3z^2-r^2)transition served as the primary excitation step. Reflectivity changes as a function of delay time reveal electronic relaxation and coherent oscillations of several optical phonon modes. Electron and phonon excitation and relaxation dynamics were studied using different polarization geometries and symmetry analysis. The interaction mechanisms of photons, electrons, and coherent phonons are discussed.

  6. Lu2O3:Pr,Hf Storage Phosphor: Compositional and Technological Issues

    Directory of Open Access Journals (Sweden)

    Aneta Wiatrowska

    2013-12-01

    Full Text Available Lu2O3:Pr,Hf ceramics were investigated using mainly thermoluminescence (TL technique. Their ability to efficiently store energy acquired upon irradiation with X-rays was proven. The best TL performance was achieved for compositions containing 0.025%–0.05% of Pr and about 0.1% of Hf. Further enhancement of TL efficiency was attained by increasing the temperature of sintering of the ceramics up to 1700 °C and applying reducing atmosphere of forming gas. It was also proven that fast cooling after the sintering at 1700 °C significantly enhanced the storage phosphor performance. TL glow curve contained three components peaking around 130, 250 and 350 °C. Among them, the one at 250 °C contributed the most to the total TL.

  7. Flux line lattice symmetries in the borocarbide superconductor LuNi2B2C

    Indian Academy of Sciences (India)

    M R Eskildsen; A B Abrahamsen; P L Gammel; D J Bishop; N H Andersen; K Mortensen; P C Canfield

    2002-05-01

    We compare the results of small angle neutron scattering on the flux line lattice (FLL) obtained in the borocarbide superconductor LuNi2B2C with the applied field along the - and -axes. For $\\mathbf{H}||\\mathbf{c}$ the temperature dependence of the FLL structural phase transition from square to hexagonal symmetry was investigated. Above 10 K the transition onset field, 2(), rises sharply, bending away from c2() in contradiction to theoretical predictions of the two merging. For $\\mathbf{H}||\\mathbf{a}$ a first order FLL reorientation transition is observed at tr =3-3.5 kOe. Below tr the FLL nearest neighbor direction is parallel to the -axis, and above tr to the -axis. This transition cannot be explained using nonlocal corrections to the London model.

  8. Effect of amplified spontaneous emission on selectivity of laser photoionisation of the 177Lu radioisotope

    Science.gov (United States)

    D'yachkov, A. B.; Gorkunov, A. A.; Labozin, A. V.; Mironov, S. M.; Panchenko, V. Ya; Firsov, V. A.; Tsvetkov, G. O.

    2016-06-01

    A significant deselecting effect of amplified spontaneous emission has been observed in the experiments on selective laser photoionisation of the 177Lu radioisotope according to the scheme 5d6s2 2D3/2 → 5d6s6p 4Fo5/2 (18505 cm-1) → 5d6s7s 4D3/2(37194 cm-1) → autoionisation state (53375 cm-1). The effect is conditioned by involvement of non-target isotopes from the lower metastable level 5d6s2 2D5/2(1994 cm-1) into the ionisation process. Spectral filtering of spontaneous emission has allowed us to significantly increase the selectivity of the photoionisation process of the radioisotope and to attain a selectivity value of 105 when using saturating light intensities.

  9. Applying LU Decomposition of Matrices to Design Anonymity Bilateral Remote User Authentication Scheme

    Directory of Open Access Journals (Sweden)

    Xiong Li

    2013-01-01

    Full Text Available We apply LU decomposition of matrices to present an anonymous bilateral authentication scheme. This paper aims at improving security and providing more excellent performances for remote user authentication scheme. The proposed scheme can provide bilateral authentication and session key agreement, can quickly check the validity of the input password, and can really protect the user anonymity. The security of the proposed scheme is based on the discrete logarithm problem (DLP, Diffie-Hellman problem (DHP, and the one-way hash function. It can resist various attacks such as insider attack, impersonation attack, server spoofing attack, and stolen smart card attack. Moreover, the presented scheme is computationally efficient for real-life implementation.

  10. Scintillation characterizations of Tl 2 LiLuCl 6 : Ce 3+ single crystal

    Science.gov (United States)

    Rooh, Gul; Kim, H. J.; Jang, Jonghun; Kim, Sunghwan

    2017-07-01

    0.5%, 1%, 3% and 5% Ce-concentration single crystals of Tl2LiLuCl6 were grown from the melt using two zone vertical Bridgman technique. X-ray induced emission spectra showed Ce3+ emission between 370 nm and 540 nm wavelength range. Energy resolution, light yield and decay time of the grown samples were measured under {\\gamma}-ray excitation at room temperature. Energy resolution of 5.6% (FWHM) with 27,000+-2700 light yield is found for 1%Ce doped sample. For the same dopant concentration, three decay time components are also observed. Variation of scintillation properties is observed as a function of dopant concentration in this material.This material will provide excellent detection efficiency for X- and {\\gamma}-rays due to its high effective Z-number and density. It is expected that this scintillor will be a potential detector for the medical imaging techniques.

  11. Anomalous charge transport in RB12 (R = Ho, Er, Tm, Lu)

    Science.gov (United States)

    Sluchanko, N.; Bogomolov, L.; Glushkov, V.; Demishev, S.; Ignatov, M.; Khayrullin, Eu.; Samarin, N.; Sluchanko, D.; Levchenko, A.; Shitsevalova, N.; Flachbart, K.

    High precision measurements of Hall RH(T) and Seebeck S(T) coefficients have been carried out for the first time on single crystals of rare earth dodecaborides RB12 (R D Ho, Er, Tm, Lu) at temperatures 1.8-300 K. Low temperature anomalies detected on the temperature dependencies of RH(T) and S(T) are associated with antiferromagnetic phase transitions in HoB12, ErB12 and TmB12 compounds. The observed discrepancy between the change of charge carriers' mobility and de-Gennes factor (g - 1)2 J(J + 1) (J - angular momentum of the 4f shell) in the set of HoB12-TmB12 allows us to conclude about the appreciable influence of spin fluctuations on the charge transport in these compounds with B12 atomic clusters.

  12. Many-body effects in LuNi{sub 2}B{sub 2}C

    Energy Technology Data Exchange (ETDEWEB)

    Bergk, B; Bartkowiak, M; Ignatchik, O; Wosnitza, J [Hochfeld-Magnetlabor Dresden (HLD), Forschungszentrum Dresden-Rossendorf, D-01314 Dresden (Germany); Petzold, V; Rosner, H [Max-Planck-Institut fuer Chemische Physik fester Stoffe, D-01187 Dresden (Germany); Drechsler, S-L; Sheikin, I [Leibniz-Institute for Solid State and Materials Research (IFW-Dresden), D-01171 Dresden (Germany); Canfield, P C, E-mail: b.bergk@fzd.d [Grenoble High Magnetic Field Laboratory, CNRS, BP 166, F-38042 Grenoble Cedex 09 (France)

    2009-03-01

    We present de Haas-van Alphen measurements of the nonmagnetic borocarbide superconductor LuNi{sub 2}B{sub 2}C. The electronic band structure is extracted from the magnetic quantum oscillations in the normal state. In accordance with previous investigations we find a complex band structure with different open and closed Fermi-surface sheets. From the temperature dependence of the oscillations amplitude the effective mass of the single bands can be determined. Due to many-body interactions we observe enhancements of the effective masses compared to the results by full-potential-density-functional calculations. Therefore, we are able to determine the angular dependence of the interaction strength for the different bands separately.

  13. A Multigrid Block LU-SGS Algorithm for Euler Equations on Unstructured Grids

    Institute of Scientific and Technical Information of China (English)

    Ruo Li; Xin Wang; Weibo Zhao

    2008-01-01

    We propose an efficient and robust algorithm to solve the steady Euler equations on unstructured grids. The new algorithm is a Newton-iteration method in which each iteration step is a linear multigrid method using block lower-upper symmetric Gauss-Seidel (LU-SGS) iteration as its smoother. To regularize the Jacobian matrix of Newton-iteration, we adopted a local residual dependent regularization as the replace ment of the standard time-stepping relaxation technique based on the local CFL number. The proposed method can be extended to high order approximations and three spatial dimensions in a nature way. The solver was tested on a sequence of benchmark prob lems on both quasi-uniform and local adaptive meshes. The numerical results illustrated the efficiency and robustness of our algorithm.

  14. High performance matrix inversion based on LU factorization for multicore architectures

    KAUST Repository

    Dongarra, Jack

    2011-01-01

    The goal of this paper is to present an efficient implementation of an explicit matrix inversion of general square matrices on multicore computer architecture. The inversion procedure is split into four steps: 1) computing the LU factorization, 2) inverting the upper triangular U factor, 3) solving a linear system, whose solution yields inverse of the original matrix and 4) applying backward column pivoting on the inverted matrix. Using a tile data layout, which represents the matrix in the system memory with an optimized cache-aware format, the computation of the four steps is decomposed into computational tasks. A directed acyclic graph is generated on the fly which represents the program data flow. Its nodes represent tasks and edges the data dependencies between them. Previous implementations of matrix inversions, available in the state-of-the-art numerical libraries, are suffer from unnecessary synchronization points, which are non-existent in our implementation in order to fully exploit the parallelism of the underlying hardware. Our algorithmic approach allows to remove these bottlenecks and to execute the tasks with loose synchronization. A runtime environment system called QUARK is necessary to dynamically schedule our numerical kernels on the available processing units. The reported results from our LU-based matrix inversion implementation significantly outperform the state-of-the-art numerical libraries such as LAPACK (5x), MKL (5x) and ScaLAPACK (2.5x) on a contemporary AMD platform with four sockets and the total of 48 cores for a matrix of size 24000. A power consumption analysis shows that our high performance implementation is also energy efficient and substantially consumes less power than its competitors. © 2011 ACM.

  15. Helical antiferromagnetic ordering in Lu1-xScxMnSi

    Energy Technology Data Exchange (ETDEWEB)

    Goetsch, Ryan J [Ames Laboratory; Anand, V K [Ames Laboratory; Johnston, David C [Ames Laboratory

    2014-08-01

    Polycrystalline samples of Lu1-xScxMnSi (x=0, 0.25, 0.5) are studied using powder x-ray diffraction, heat capacity Cp, magnetization, magnetic susceptibility χ, and electrical resistivity ρ measurements versus temperature T and magnetic field H. This system crystallizes in the primitive orthorhombic TiNiSi-type structure (space group Pnma) as previously reported. The ρ(T) data indicate metallic behavior. The Cp(T), χ(T), and ρ(T) measurements consistently indicate long-range antiferromagnetic (AF) transitions with AF ordering temperatures TN=246, 215, and 188 K for x=0, 0.25, and 0.5, respectively. A second transition is observed at somewhat lower T for each sample from the χ(T) and ρ(T) measurements, which we speculate are due to spin reorientation transitions; these second transitions are completely suppressed in H=5.5 T. The Cp data below 10 K for each composition indicate an enhanced Sommerfeld electronic heat capacity coefficient for the series in the range γ=24–29 mJ/mol K2. The χ(T) measurements up to 1000 K were fitted by local-moment Curie-Weiss behaviors which indicate a low Mn spin S~1. The χ data below TN are analyzed using the Weiss molecular field theory for a planar noncollinear cycloidal AF structure with a composition-dependent pitch, following the previous neutron diffraction work of Venturini et al. [J. Alloys Compd. 256, 65 (1997)]. Within this model, the fits indicate a turn angle between Mn ordered moments along the cycloid axis of ~100° or ~145°, either of which indicate dominant AF interactions between the Mn spins in the Lu1-xScxMnSi series of compounds.

  16. 应用GAO-YONG湍流模式数值模拟三维激波/湍流边界层干扰%Numerical simulation of 3-D shock wave/turbulent boundary layer interaction using GAO-YONG turbulence model

    Institute of Scientific and Technical Information of China (English)

    闫文辉; 高歌; YONG Yan

    2009-01-01

    应用GAO-YONG可压缩湍流模式数值模拟了三维激波/湍流边界层干扰算例之一--单鳍流动.攻角20°,来流马赫数2.93,雷诺数9.8×105.对流项和扩散项分别采用Roe格式和二阶中心差分格式计算.Runge-Kutta显示时间推进方法求解了半离散的控制方程.包括壁面压力分布,边界层内流动偏移角等在内的计算值与试验数据进行了比较.准确地预测出了三维激波/湍流边界层干扰流场的主要流动特性--A波结构,主分离涡核,膨胀区,滑移线等.计算与Alvi等提出的单鳍流动的理论模型符合很好,得到了平板表面压力以及分离线、再附线等在单鳍流动中所独有的半圆锥特性.

  17. 张杲《医说》版本知见录%An introduction on the editions of Zhang Gao's Yi shuo (Medical Narrations)

    Institute of Scientific and Technical Information of China (English)

    王旭光; 陆翔

    2014-01-01

    Zhang Gao's Yi shuo (Medical Narrations) of the Southern Song Dynasty had 2 kinds of editions:domestic editions and foreign editions.The former includes 1 Song edition,14 Ming editions,3 Qing editions and 25 editions after the Republic of China.The latter,mainly 2 classes,the Japanese edition and Korean printing type edition.In the Ming Dynasty,the editions of Yi shuo generated 2 branches:inherited edition and supplementary edition.The inherited editions include Gu Dingfang's edition,Zhang Yaode's edition,Wu Mianxue's edition,Wu Zhongheng's edition,Wang Kentang's edition,editions from Si ku quan shu (Imperial Collection of Four),stereotype edition of the 3th year of Xuantong reign (1911) from Shanghai Civilization Bookstore,edition of the 2nd year of Manji of Japan etc.The supplemental editions inelude Zhang Zili's edition,Shen Fan's edition,Fu Feng'ao's edition,transcript of the late Ming Dynasty preserved in the Library of Peking University,and Korean printing type edition etc.%南宋医家张杲的《医说》有国内出版本和国外出版本2类.国内出版本可分为宋本、明本、清本、民国以来诸本,目前可以知见宋本1种、明本14种、清本3种、民国以来诸本25种.国外出版本主要有日本刊本、朝鲜活字本2类.《医说》的版本,在明代产生了原本传承本和增补本2个分支.原本传承本有顾定芳刊本、张尧德刊本、吴勉学刊本、吴中珩刊本、王肯堂刊本、《四库全书》诸本、清宣统三年(1911)上海文明书局铅字排印本、日本万治二年(1659)刊本等.增补本有张子立刊本、沈藩刊本、傅凤翱刊本、北京大学图书馆藏明末抄本、朝鲜活字本等.

  18. Role Discussion on "The Silent People"in Gao Xingjian's Play%高行健戏剧中“沉默的人”角色探析

    Institute of Scientific and Technical Information of China (English)

    马炜

    2015-01-01

    The setting of the characters in some plays of Gao Xingjian is relatively simple,even only two people can be found in some plays.Except the simple relations of characters,there is another role that doesn’t join the dialogue.For example,"the silent people"in The Station,"the retired old man "in The Shelter from the Rain,"the monk"in The Dialogue and Backchat.They only have gestures and expressions.They are not involved in the plot,but still can be considered as an indispensable part of the play,just like other characters.These characters express themselves by silent actions and emotions,which become more dramatic and amusing.They make some polyphonic effects and open up multilevel spaces.%高行健的一些戏剧人物设置比较简单甚至有些剧目只有两个人对话,但是在简单的人物关系之外,会设置一个不参与剧中对话的角色。比如:《车站》中的“沉默的人”,《躲雨》中的“退休老人”,《对话与反诘》中的“和尚”。这类角色在各自剧中只有动作和表情,游离于剧情之外但又贯穿整部戏,和其他角色一起构成戏剧不可或缺的一环。这类角色通过无声的动作和具象的表情进行表演和言说,增强了戏剧性和观赏性。客观上产生一种复调效果,开拓了戏剧多层的意义空间。

  19. Lu.sub.1-xI.sub.3:Ce.sub.x-a scintillator for gamma-ray spectroscopy and time-of-flight pet

    Science.gov (United States)

    Shah, Kanai S [Newton, MA

    2008-02-12

    The present invention includes very fast scintillator materials including lutetium iodide doped with Cerium (Lu.sub.1-xI.sub.3:Ce.sub.x; LuI.sub.3:Ce). The LuI.sub.3 scintillator material has surprisingly good characteristics including high light output, high gamma-ray stopping efficiency, fast response, low cost, good proportionality, and minimal afterglow that the material is useful for gamma-ray spectroscopy, medical imaging, nuclear and high energy physics research, diffraction, non-destructive testing, nuclear treaty verification and safeguards, and geological exploration.

  20. On Yang Xianyi and Gladys Yang’s Translation of Lu Xun’s My Old Home from the Perspective of Functional Equivalence

    Institute of Scientific and Technical Information of China (English)

    王常珏

    2015-01-01

    Lu Xun has many classic works which are translated into English.Because of special traditional culture,the work contains a bright feature of the times and nationality characteristics.These cultural factors become the most difficult part in translation.Yang Xianyi and Gladys Yang’s translation of Lu xun’s work is the most famous one among so many translations.This paper will study Yang Xianyi and Gladys Yang’s translation of Lu Xun’s My Old Home from the perspective of Functional Equivalence.According to Functional Equivalence,it will appreciate the work from the title,cultureloaded word and dialect.

  1. Lu.sub.1-xI.sub.3:Ce.sub.x-a scintillator for gamma-ray spectroscopy and time-of-flight pet

    Science.gov (United States)

    Shah, Kanai S.

    2008-02-12

    The present invention includes very fast scintillator materials including lutetium iodide doped with Cerium (Lu.sub.1-xI.sub.3:Ce.sub.x; LuI.sub.3:Ce). The LuI.sub.3 scintillator material has surprisingly good characteristics including high light output, high gamma-ray stopping efficiency, fast response, low cost, good proportionality, and minimal afterglow that the material is useful for gamma-ray spectroscopy, medical imaging, nuclear and high energy physics research, diffraction, non-destructive testing, nuclear treaty verification and safeguards, and geological exploration.

  2. On Yang Xianyi and Gladys Yang’s Translation of Lu Xun’s My Old Home from the Perspective of Functional Equivalence

    Institute of Scientific and Technical Information of China (English)

    王常珏

    2015-01-01

    Lu Xun has many classic works which are translated into English.Because of special traditional culture,the work contains a bright feature of the times and nationality characteristics.These cultural factors become the most difficult part in translation.Yang Xianyi and Gladys Yang’s translation of Lu xun’s work is the most famous one among so many translations.This paper will study Yang Xianyi and Gladys Yang’s translation of Lu Xun’s My Old Home from the perspective of Functional Equivalence.According to Functional Equivalence,it will appreciate the work from the title,culture-loaded word and dialect.

  3. 高普运用补阳还五汤治疗糖尿病多汗症经验%The experience of Gao Pu apply Bu Yang Huai Wu decoction in the treatment of diabetes hyperhidrosis

    Institute of Scientific and Technical Information of China (English)

    尹丽媛

    2014-01-01

    高普教授认为糖尿病多汗症的基本病机为气阴两虚、气血瘀滞。当以益气养阴、活血化瘀为治则。高教授采用“异病同治”之法,应用益气活血的代表方剂补阳还五汤,合并生脉散、玉屏风散、麦味地黄汤、当归六黄汤等,辨证治疗多汗症获效良多。%Professor Gao Pu considers that the basic pathogenesis of diabetes hyperhidrosis is deficiency of both qi and yin,qi and blood stasis.The treatment principle is tonifying qi and yin,promoting blood circulation to remove blood stasis.Professor Gao use"treating different diseases with same method",apply representative prescription Bu Yang Huai Wu decoction of benefiting qi for activating blood circulation combined with shengmai powders,Yu Ping Feng San,Mai Wei Di Huang decoction, Dangguiliuhuang decoction and so on.Syndrome differentiation and treatment in hyperhidrosis has many effects.

  4. 优化高氏Ⅰ号培养基在泰乐菌素菌种培养中的应用%Optimization of Gao I Culture Medium in Tylosin Production

    Institute of Scientific and Technical Information of China (English)

    张丽; 张萍; 石彦鹏; 马燕

    2012-01-01

    通过向高氏I号培养基中加入一定量的豆饼粉、酵母浸膏粉和玉米浆,对配方进行优化调整用于泰乐菌素产生菌的培养,与原有的麸皮斜面进行对比。结果表明在高氏I号培养基中加豆饼粉和酵母浸膏粉使斜面生长周期缩短至8~9 d,同时减小斜面批与批之间差异,数据分析进一步表明改进的高氏I号培养基提高了菌种生产水平,同时产生大量优质孢子。%Through the Gao I culture medium by adding a certain amount of soybean flour,yeast extract powder and corn syrup,the formula for optimal adjustment for tylosin producing bacteria was contrasted with the original bran slant culture medium.The results showed that in Gao I culture medium with soybean flour and yeast extract powder were reduced the slope growth cycle shortens to 8~ 9 d,at the same time,the analysis data that produced more quality and stabilized and improved strain production level.

  5. Structural, electronic, optical and thermodynamic properties of cubic REGa{sub 3} (RE = Sc or Lu) compounds: Ab initio study

    Energy Technology Data Exchange (ETDEWEB)

    Murtaza, G., E-mail: murtaza@icp.edu.pk [Materials Modeling Laboratory, Department of Physics, Islamia College Peshawar (Pakistan); Gupta, S.K. [Department of Physics, Michigan Technological University, Houghton, MI 49931 (United States); Seddik, T. [Laboratoire de Physique Quantique et de Modélisation Mathématique, Université de Mascara, 29000 Mascara (Algeria); Khenata, R., E-mail: khenata_rabah@yahoo.fr [Laboratoire de Physique Quantique et de Modélisation Mathématique, Université de Mascara, 29000 Mascara (Algeria); Alahmed, Z.A. [Department of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451 (Saudi Arabia); Ahmed, R. [Department of Physics, Faculty of Science, Universiti Teknologi Malaysia, UTM Skudai, 81310 Johor (Malaysia); Khachai, H. [Physics Department, Djillali Liabes University of Sidi Bel-Abbes (Algeria); Jha, P.K. [Department of Physics, Maharaja Krishnakumarsinhji Bhavnagar University, Bhavnagar 364001 (India); Bin Omran, S. [Department of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451 (Saudi Arabia)

    2014-06-01

    Highlights: • REGa{sub 3} (RE = Sc or Lu) compounds are mechanical stabile. • Both ScGa{sub 3} and LuGa{sub 3} exhibit metallic behavior just like other REGa{sub 3} compounds. • Melting temperature T{sub m} (K) for ScGa{sub 3} and LuGa{sub 3} are 1244.2 and 1143.8. • High absorption observed in the visible energy region. • The present study would be helpful for future experimental/theoretical explorations. - Abstract: Structural, elastic, optoelectronic and thermodynamic properties of REGa{sub 3} (RE = Sc and Lu) compounds have been studied self consistently by employing state of the art full potential (FP) linearized (L) approach of augmented plane wave (APW) plus local orbitals method. Calculations were executed at the level of Perdew–Burke and Ernzerhof (PBE) parameterized generalized gradient approximation (GGA) for exchange correlation functional in addition to modified Becke–Johnson (mBJ) potential. Our obtained results of lattice parameters show reasonable agreement to the previously reported experimental and other theoretical studies. Analysis of the calculated band structure of ScGa{sub 3} and LuGa{sub 3} compounds demonstrates their metallic character. Moreover, a positive value of calculated Cauchy pressure, in addition to reflecting their ductile nature, endorses their metallic character as well. To understand optical behavior calculations related to the important optical parameters; real and imaginary parts of the dielectric function, reflectivity R(ω), refractive index n(ω) and electron energy-loss function L(ω) have also been performed. In the present work, thermodynamically properties are also investigated by employing lattice vibrations integrated in quasi harmonic Debye model. Obtained results of volume, heat capacity and Debye temperature as a function of temperature for both compounds, at different values of pressure, are found to be consistent. The calculated value of melting temperature for both compounds (ScGa{sub 3} and Lu

  6. Tumoral fibrosis effect on the radiation absorbed dose of {sup 177}Lu-Tyr{sup 3}-octreotate-gold nanoparticles and {sup 177}Lu-Tyr{sup 3}-octreotate radiopharmaceuticals

    Energy Technology Data Exchange (ETDEWEB)

    Zambrano R, O. D.

    2015-07-01

    In this work was comparatively evaluated the effect of tumoral fibrosis in the radiation absorbed dose of the radiopharmaceutical {sup 177}Lu-Tyr{sup 3}-octreotate with and without gold nanoparticles. For this, was used an experimental array of tumoral fibrosis and computer models based on Monte Carlo calculations to simulate tumoral micro environments without fibrosis and with fibrosis. The computer simulation code Penelope (Penetration Energy Loss of Positron and Electrons) and MCNP (Monte Carlo N-particle Transport Code System) which are based on the Monte Carlo methodology were used to create the computer models for the simulation of the transport of particles (emitted by {sup 177}Lu) in the micro environments (without fibrosis and with fibrosis) with the purpose of calculating the radiation absorbed dose in the interstitial space and in the nucleus of cancer cells. The first computational model consisted of multiple concentric spheres (as onion shells) with the radioactive source homogeneously distributed in the shell between 5 and 10 μm in diameter which represents the internalization of the radioactive source into the cell cytoplasm as it occurs in target specific radiotherapy. The concentric spheres were useful to calculate the radiation absorbed dose in depth in the models without fibrosis and with fibrosis. Furthermore, there were constructed other computer models using two different codes that simulate the transport of radiation (Penelope and MCNP). These models consist of seven spheres that represent cancer cells (HeLa cells) of 10 μm in diameter and each one of them contain another smaller sphere in the center that represents the cell nucleus. A comparison was done of the radiation absorbed dose in the nucleus of the cells, calculated with both codes, Penelope and MCNP. The radioactive source ({sup 177}Lu) used for the simulations was given to the codes by means of a convoluted spectrum of the most important beta particles (high percentage emission

  7. Synthesis and Luminescent Properties of LuAG: Ce3+ Transoarent Ceramics by Solvo-Thermal Method%Synthesis and Luminescent Properties of LuAG : Ce3+ Transparent Ceramics by Solvo-Thermal Method

    Institute of Scientific and Technical Information of China (English)

    WANG Lin-xiang; ZHU Heng-jiang; WU Ling-yuan; DENG Kai-mo; GUO Chang-xin; YIN Min

    2011-01-01

    The precursor powders of LuAG: Ce3+ transparent ceramics were synthesized by solvo-thermal method. The crystal structure and morphology of powders were analyzed by means of Fourier transform infrared spectroscopy, X-ray diffraction and scanning electron microscopy. The precursor powders were sintered into transparent ceramics in vacuum and then in nitrogen without any additive. The surface morphology of the transparent unpolished ceramics was characterized using scanning electron microscopy. Some factors that affect the transparency of ceramics were discussed. The UV-Vis fluorescence excitation and emission spectra of LuAG: Ce3+ transparent ceramics were measured. The vacuum ultraviolet spectra of transparent ceramics were investigated using the synchrotron radiation as the excitation source. The excitation mechanism of Ce3+ was discussed at different excitation wavelength.

  8. Lu-Hf and Sm-Nd geochronology of garnet gneisses in the central Appalachians, U.S.: Implications for the timing and duration of Grenville Orogeny

    Science.gov (United States)

    Vervoort, Jeff; Ramsey, Molly; Mulcahy, Sean; Aleinikoff, John; Southworth, Scott

    2014-05-01

    The Grenville orogeny is one of the most significant geological events in Earth's history with remnants of this event prominent on virtually every continent. Constraining its timing and duration is important not only for understanding the tectonics of the Grenville itself, but also for understanding supercontinent cycles and other questions of Earth's evolution. In order to provide better constraints on the timing of Grenvillian metamorphism, we analyzed garnet-bearing Mesoproterozoic ortho and paragneisses, collected along a 150 km transect in the northern Blue Ridge Province, using combined Lu-Hf and Sm-Nd geochronology. The orthogneisses have U-Pb zircon crystallization ages of ~1140 and 1100 Ma. The paragneisses have maximum depositional ages ~1050 to 1020 Ma, based on the youngest detrital zircon populations. Zircon overgrowths and monazite ages suggest metamorphic events between ~1050 and 960 Ma. The Lu-Hf and Sm-Nd data for these samples both yield robust garnet ages with large spread of parent/daughter ratios, low age uncertainties, and low MSWD values. Lu-Hf ages define a narrow time span (1043±12 Ma to 1016±4 Ma; wtd. mean, 1024±7 Ma, 2σ). The Sm-Nd ages, determined on the same solutions as Lu-Hf, also define a narrow time range but are systematically younger (974±11 Ma to 932±5 Ma; wtd. mean, 957±10 Ma). The average difference between Lu-Hf and Sm-Nd ages is 67 Ma; the oldest Sm-Nd age is 40 Ma younger than the youngest Lu-Hf age. These large systematic differences in the ages are enigmatic. While Sm-Nd ages younger than Lu-Hf are not uncommon, these differences are typically small. There are, however, potential explanations for these differences. (1) Lu partitions strongly into garnet during growth resulting in high Lu/Hf ratios in the core and yielding ages weighted toward the beginning of growth (e.g., Skora, 2006); no similar partitioning exists in Sm/Nd and these ages reflect mean garnet growth. (2) Lu diffuses much faster than Hf at elevated

  9. Assessment of the land use/land cover (LU/LC) and mangrove changes along the Mandovi–Zuari Estuarine complex of Goa, India

    Digital Repository Service at National Institute of Oceanography (India)

    Misra, A.; ManiMurali, R.; Vethamony, P.

    , 2001 and 2011. Considering a spectrally heterogeneous landscape of the region, the LU/LC changes are identified by using principal component analysis (PCA) as a pre-classification step, followed by the implementation of a combination of supervised...

  10. Materials and Electrical Characterization of Physical Vapor Deposited LaxLu1-xO3 Thin Films on 300 mm Silicon

    Energy Technology Data Exchange (ETDEWEB)

    L Edge; T Vo; V Paruchuri; R Iijima; J Bruley; J Jordan-Sweet; B Linder; A Kellock; T Tsunoda; S Shinde

    2011-12-31

    La{sub x}Lu{sub 1-x}O{sub 3} thin films were deposited on 300 mm silicon wafers by physical vapor deposition and fabricated into field-effect transistors using a gate-first process flow. The films were characterized using transmission electron microscopy, Rutherford backscattering spectrometry, and synchrotron x-ray diffraction. The results show the films remain amorphous even at temperatures of 1000 C. The dielectric properties of La{sub x}Lu{sub 1-x}O{sub 3} (0.125 {<=} x {<=} 0.875) thin films were evaluated as a function of film composition. The amorphous La{sub x}Lu{sub 1-x}O{sub 3} thin films have a dielectric constant (K) of 23 across the composition range. The inversion thickness (T{sub inv}) of the La{sub x}Lu{sub 1-x}O{sub 3} thin films was scaled to <1.0 nm.

  11. Potentiometric and spectral studies of complex formation of La(III), Pr(III) and Lu(III) with aspartic acid and asparagine

    Energy Technology Data Exchange (ETDEWEB)

    Wojciechowska, A.; Lomozik, L.; Zielinski, S.

    1987-12-01

    The composition and stability of La/sup 3 +/, Pr/sup 3 +/ and Lu/sup 3 +/ complexes with aspartic acid and asparagine were analysed. The formation of complexes of the type ML and MHL was determined for La/sup 3 +/ and Pr/sup 3 +/ with aspartic acid, and of the type MHL for Lu/sup 3 +/ with aspartic acid. For La/sup 3 +/, Pr/sup 3 +/ and Lu/sup 3 +/ with asparagine the formation of ML(OH) complexes was observed. By means of /sup 1/H NMR and /sup 13/C NMR studies the participation in the coordination of both -COOH groups was determined for aspartic acid, whereas for asparagine the participation of the -COOH group was determined in complexes with La/sup 3 +/, Pr/sup 3 +/, and of the -COOH and the -NH/sub 2/ groups in the complex with Lu/sup 3 +/.

  12. Formulation of an inhibitor radiopharmaceutical of prostatic antigen of {sup 177}Lu-Glu-Nh-CO-Nh-Lys membrane; Formulacion de un radiofarmaco inhibidor del antigeno prostatico de membrana {sup 177}Lu-Glu-NH-CO-NH-Lys

    Energy Technology Data Exchange (ETDEWEB)

    Ortega S, D.

    2015-07-01

    The prostate specific membrane antigen (PSMA) is a zinc metalloenzyme that is expressed on the cell membrane and highly expressed in prostate cancer. Recently, it has been demonstrated that the peptide sequence Glu-Nh-CO-Nh-Lys inhibit PSMA activity through an electrostatic interaction with the Zn. Several theragnostic radiopharmaceuticals with base in {sup 177}Lu have been developed for radiotherapy of specific molecular targets because gamma and beta emissions of the radionuclide (β = 0.498 MeV and γ= 0.133 MeV). However, there is currently no label a formulation for preparing a radiopharmaceutical of {sup 177}Lu-Glu-Nh-CO-Nh-Lys useful treatment of prostate cancer. The aim of this research was to optimize and document the process of production of the radiopharmaceutical {sup 177}Lu-Glu-Nh-CO-Nh-Lys for sanitary registration application before the Comision Federal para la Proteccion contra Riesgos Sanitarios (COFEPRIS). The optimization of the production process was assessed a factorial design of three variables with mixed levels (3 x 3 x 2) where the dependent variable is the radiochemical purity, the analytical method was validated by UV-Vis spectrophotometry. Next, process validation was carried out by labeling 3 lots of the optimized formulation of the radiopharmaceutical (5.55 GBq (2.16 μg) of {sup 177}LuCl{sub 3}, 90 mg peptide PSMA, 50 mg ascorbic acid and 150 μL of acetate buffer 1 M ph 5), long-term stability was performed by high resolution liquid chromatography) to determine its useful shelf life. 3 validation batches were prepared under protocols of Good Manufacturing Practice (GMP) in the Production Plant of Radiopharmaceuticals of the Instituto Nacional de Investigaciones Nucleares (ININ), meet specifications preset by obtaining a sterile and free development of bacterial endotoxin yields of labeled 100% and which retains its quality characteristics radiochemical purity greater than 90% for at least 15 days. (Author)

  13. {sup 177}Lu-immunotherapy of experimental peritoneal carcinomatosis shows comparable effectiveness to {sup 213}Bi-immunotherapy, but causes toxicity not observed with {sup 213}Bi

    Energy Technology Data Exchange (ETDEWEB)

    Seidl, Christof; Zoeckler, Christine; Beck, Roswitha; Senekowitsch-Schmidtke, Reingard [Technische Universitaet Muenchen, Department of Nuclear Medicine, Munich (Germany); Quintanilla-Martinez, Leticia [Universitaetsklinikum Tuebingen, Institute for Pathology, Tuebingen (Germany); Bruchertseifer, Frank [Institute for Transuranium Elements, European Commission, Joint Research Centre, Karlsruhe (Germany)

    2011-02-15

    {sup 213}Bi-d9MAb-immunoconjugates targeting gastric cancer cells have effectively cured peritoneal carcinomatosis in a nude mouse model following intraperitoneal injection. Because the {beta}-emitter {sup 177}Lu has proven to be beneficial in targeted therapy, {sup 177}Lu-d9MAb was investigated in this study in order to compare its therapeutic efficacy and toxicity with those of {sup 213}Bi-d9MAb. Nude mice were inoculated intraperitoneally with HSC45-M2 gastric cancer cells expressing d9-E-cadherin and were treated intraperitoneally 1 or 8 days later with different activities of specific {sup 177}Lu-d9MAb immunoconjugates targeting d9-E-cadherin or with nonspecific {sup 177}Lu-d8MAb. Therapeutic efficacy was evaluated by monitoring survival for up to 250 days. For evaluation of toxicity, both biodistribution of {sup 177}Lu-d9MAb and blood cell counts were determined at different time points and organs were examined histopathologically. Treatment with {sup 177}Lu-immunoconjugates (1.85, 7.4, 14.8 MBq) significantly prolonged survival. As expected, treatment on day 1 after tumour cell inoculation was more effective than treatment on day 8, and specific {sup 177}Lu-d9MAb conjugates were superior to nonspecific {sup 177}Lu-d8MAb. Treatment with 7.4 MBq of {sup 177}Lu-d9MAb was most successful, with 90% of the animals surviving longer than 250 days. However, treatment with therapeutically effective activities of {sup 177}Lu-d9MAb was not free of toxic side effects. In some animals lymphoblastic lymphoma, proliferative glomerulonephritis and hepatocarcinoma were seen but were not observed after treatment with {sup 213}Bi-d9MAb at comparable therapeutic efficacy. The therapeutic efficacy of {sup 177}Lu-d9MAb conjugates in peritoneal carcinomatosis is impaired by toxic side effects. Because previous therapy with {sup 213}Bi-d9MAb revealed comparable therapeutic efficacy without toxicity it should be preferred for the treatment of peritoneal carcinomatosis. (orig.)

  14. Quantitative analysis of T-wave morphology increases confidence in drug-induced cardiac repolarization abnormalities: evidence from the investigational IKr inhibitor Lu 35-138

    DEFF Research Database (Denmark)

    Graff, Claus; Matz, Jørgen; Christensen, Ellen B;

    2009-01-01

    to determine a combined measure of repolarization morphology (morphology combination score [MCS]), based on asymmetry, flatness, and notching. Replicate measurements were used to determine reliable change and study power for both measures. Lu 35-138 increased the QTc interval with corresponding changes in T...... was 93%. As a covariate to the assessment of QT interval liability, MCS offered important additive information to the effect of Lu 35-138 on cardiac repolarization....

  15. Subsolidus Phase Relations of the CaO-REOx-CuO Systems (RE = Eu, Tb, Dy, Ho, Er, Lu and Sc) at 900 °C in Air

    DEFF Research Database (Denmark)

    Grivel, Jean-Claude

    2016-01-01

    The subsolidus phase relations of the CaO-REOx-CuO systems (RE = Eu, Tb, Dy, Ho, Er, Lu and Sc) were investigated in air at 900 °C. The pseudo-ternary sections with RE = Tb, Dy, Ho, Er and Lu have a similar structure. They have in common with the RE = Eu system a solid solution of Ca0.833−xRExCuO2...... in the other systems at 900 °C in air....

  16. 33000 photons per MeV from mixed (Lu0.75Y0.25)3Al5O12:Pr scintillator crystals

    NARCIS (Netherlands)

    Drozdowski, W.; Brylew, K.; Wojtowicz, A.J.; Kisielewski, J.; Swirkowicz, M.; Lukasiewicz, T.; De Haas, J.T.M.; Dorenbos, P.

    2014-01-01

    (LuxY1-x)3Al5O12:Pr (x = 0.25, 0.50, 0.75) crystals have been grown by the Czochralski method and their scintillation properties have been examined. Compared to the well-respected LuAG:Pr scintillator, which has so extensively been studied in the recent years, the new mixed LuYAG:Pr crystals display

  17. Feasibility and utility of re-treatment with {sup 177}Lu-DOTATATE in GEP-NENs relapsed after treatment with {sup 90}Y-DOTATOC

    Energy Technology Data Exchange (ETDEWEB)

    Severi, Stefano; Sansovini, Maddalena; Ianniello, Annarita; Nicolini, Silvia; Caroli, Paola; Paganelli, Giovanni [Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Nuclear Medicine Unit, Meldola, FC (Italy); Bodei, Lisa [European Institute of Oncology, Division of Nuclear Medicine, Milan (Italy); Ibrahim, Toni [Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Osteoncology and Rare Tumors Center, Meldola (Italy); Di Iorio, Valentina [Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Oncology Pharmacy Laboratory, Meldola (Italy); D' Errico, Vincenzo [Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Medical Physics Unit, Meldola (Italy); Monti, Manuela [Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Unit of Biostatistics and Clinical Trials, Meldola (Italy)

    2015-12-15

    Peptide receptor radionuclide therapy (PRRT) is a valid therapy for grade 1/2 gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs). Although a median progression-free survival (PFS) of more than 20 months is frequently observed, the majority of patients relapse after 2 - 3 years. In the present study, we investigated the use of low dosage re-treatment with {sup 177}Lu-DOTATATE (Lu-PRRT) in patients with GEP-NENs who relapsed after treatment with {sup 90}Y-DOTATOC (Y-PRRT). Upon tumour progression, 26 patients with a PFS of at least 12 months after Y-PRRT were consecutively enrolled in a phase II study of re-treatment with Lu-PRRT. All patients had preserved kidney and haematological parameters and received 14.8 - 18.5 GBq of Lu-PRRT in four or five cycles. The disease control rate (DCR), toxicity, PFS and prognostic factors were evaluated. Median total activity of Lu-PRRT was 16.5 GBq in five cycles. The DCR was 84.6 %, median PFS was 22 months (95 % CI 16 months - not reached) compared to 28 months (95 % CI 20 - 36 months) after Y-PRRT. Tumour burden and number of liver metastases were important prognostic factors. Toxicity was mild after Lu-PRRT re-treatment in the majority of patients, with only two patients with grade 2 and one with grade 3 bone marrow toxicity; one patient had grade 2 and one grade 3 renal toxicity. Patients with GEP-NEN who have previously responded to Y-PRRT are suitable candidates for Lu-PRRT re-treatment on progression. Although our sample size was limited, low-dosage Lu-PRRT was safe, and led to DCR and PFS rates comparable with those observed when Y-PRRT was used as primary treatment. (orig.)

  18. Energy Levels and Intensity Parameters of Ho3(+) Ions in Y3Al5O12 and Lu3Al5O12

    Science.gov (United States)

    Walsh, Brian M.; Grew, Gary W.; Barnes, Norman P.

    2006-01-01

    The energy levels of the trivalent lanthanide Ho(sup 3+) in Y3Al5O12 (YAG) and Lu3Al5O12 (LuAG) have been measured. The Stark split levels for the first nine Ho manifolds in these materials have been measured, and the results have been fit to a free ion plus crystal field Hamiltonian to generate a theoretical set of energy levels. Crystal field parameters were varied to determine the best fit between experimental and theoretical energy levels. The energy levels of Ho:LuAG are seen to be very similar to those in Ho:YAG. However, subtle changes resulting from replacing Y(sup 3+) with Lu(sup 3+) in the garnet crystal Y3Al5O12 result in different transition wavelengths in LuAG. This has implications for Ho (sup 5)I7yields (sup 5)I8 lasers operating at approximately 2.1 micrometers. Although the energy levels have been measured previously in Ho:YAG, they have not been measured in Ho:LuAG. A comparison of the energy levels in Ho:YAG measured here show some discrepancies with previous measurements. The consistency of the energy level placement between Ho:LuAG and Ho:YAG indicate that the earlier studies may have some errors in the assignments. Finally, a Judd-Ofelt analysis is performed on Ho:YAG and Ho:LuAG to determine the intensity parameters, and thus, the transition probabilities and branching ratios of the first eight excited manifolds.

  19. {sup 177}Lu-DOTATATE therapy in patients with neuroendocrine tumours: 5 years' experience from a tertiary cancer care centre in India

    Energy Technology Data Exchange (ETDEWEB)

    Danthala, Madhav; Raghavendra Rao, M. [HCG Oncology Hospitals, Bangalore, Karnataka (India); Kallur, K.G.; Prashant, G.R.; Rajkumar, K. [HCG Oncology Hospitals, Department of Nuclear Medicine, Bangalore, Karnataka (India)

    2014-07-15

    The choice of an appropriate treatment option in patients with inoperable or metastatic neuroendocrine tumours (NETs) is limited, and approximately 50 % of patients have advanced NET at diagnosis, and 65 % die within 5 years. Treatment with {sup 177}Lu-DOTATATE ({sup 177}Lu-[DOTA{sup 0},Tyr{sup 3}] octreotate) is a promising new option in the treatment of metastatic NETs. Patients with metastatic NET who underwent {sup 177}Lu-DOTATATE during the period 2009 to 2013 were included in this retrospective study. Follow-up imaging studies including a {sup 68}Ga-DOTANOC PET/CT scan and a posttherapy {sup 177}Lu-DOTATATE scan were compared with baseline imaging to determine response to treatment. Progression-free survival (PFS) was calculated using the Kaplan-Meier method and Cox regression analysis was also done. Ten patients (25 %) had a minimal response, 13 (32.5 %) had a partial response and 9 (22.5 %) had stable disease. Progressive disease was seen in 8 patients (20 %), including 6 patients who died during or after the treatment period. The estimated mean PFS in those who received one or two cycles of {sup 177}Lu-DOTATATE was 8.3 months (95 % CI 6.2 to 10.3 months) compared to an estimated mean PFS of 45.6 months (95 % CI 40.9 to 50.2 months) in those who received more than two cycles of {sup 177}Lu-DOTATATE (log-rank Mantel-Cox Χ {sup 2} = 8.01, p = 0.005). Our study showed that treatment with {sup 177}Lu-DOTATATE should be considered in the management of NETs, considering the limited success of alternative treatment modalities. Treatment response and PFS is determined primarily by the dose delivered and best results are obtained when more than two cycles of {sup 177}Lu-DOTATATE are given, with careful monitoring for possible side effects. (orig.)

  20. Somatostatin-based radiopeptide therapy with [{sup 177}Lu-DOTA]-TOC versus [{sup 90}Y-DOTA]-TOC in neuroendocrine tumours

    Energy Technology Data Exchange (ETDEWEB)

    Romer, A.; Seiler, D.; Brunner, P.; Ng, Q.K.T.; Mueller-Brand, J. [University Hospital Basel, Institute of Nuclear Medicine, Basel (Switzerland); Marincek, N.; Walter, M.A. [University Hospital Basel, Institute of Nuclear Medicine, Basel (Switzerland); University Hospital Bern, Institute of Nuclear Medicine, Bern (Switzerland); Koller, M.T. [University Hospital Basel, Basel Institute for Clinical Epidemiology and Biostatistics, Basel (Switzerland); Maecke, H.R. [University Hospital Basel, Division of Radiochemistry, Basel (Switzerland); Rochlitz, C. [University Hospital Basel, Department of Oncology, Basel (Switzerland); Briel, M. [University Hospital Bern, Institute of Nuclear Medicine, Bern (Switzerland); University Hospital Basel, Basel Institute for Clinical Epidemiology and Biostatistics, Basel (Switzerland); McMaster University, Department of Clinical Epidemiology and Biostatistics, Hamilton (Canada); Schindler, C. [University of Basel, Swiss Tropical and Public Health Institute, Basel (Switzerland)

    2014-02-15

    Somatostatin-based radiopeptide treatment is generally performed using the β-emitting radionuclides {sup 90}Y or {sup 177}Lu. The present study aimed at comparing benefits and harms of both therapeutic approaches. In a comparative cohort study, patients with advanced neuroendocrine tumours underwent repeated cycles of [{sup 90}Y-DOTA]-TOC or [{sup 177}Lu-DOTA]-TOC until progression of disease or permanent adverse events. Multivariable Cox regression and competing risks regression were employed to examine predictors of survival and adverse events for both treatment groups. Overall, 910 patients underwent 1,804 cycles of [{sup 90}Y-DOTA]-TOC and 141 patients underwent 259 cycles of [{sup 177}Lu-DOTA]-TOC. The median survival after [{sup 177}Lu-DOTA]-TOC and after [{sup 90}Y-DOTA]-TOC was comparable (45.5 months versus 35.9 months, hazard ratio 0.91, 95 % confidence interval 0.63-1.30, p = 0.49). Subgroup analyses revealed a significantly longer survival for [{sup 177}Lu-DOTA]-TOC over [{sup 90}Y-DOTA]-TOC in patients with low tumour uptake, solitary lesions and extra-hepatic lesions. The rate of severe transient haematotoxicities was lower after [{sup 177}Lu-DOTA]-TOC treatment (1.4 vs 10.1 %, p = 0.001), while the rate of severe permanent renal toxicities was similar in both treatment groups (9.2 vs 7.8 %, p = 0.32). The present results revealed no difference in median overall survival after [{sup 177}Lu-DOTA]-TOC and [{sup 90}Y-DOTA]-TOC. Furthermore, [{sup 177}Lu-DOTA]-TOC was less haematotoxic than [{sup 90}Y-DOTA]-TOC. (orig.)

  1. Reconciliation of the excess 176Hf conundrum in meteorites: Recent disturbances of the Lu-Hf and Sm-Nd isotope systematics

    Science.gov (United States)

    Bast, Rebecca; Scherer, Erik E.; Sprung, Peter; Mezger, Klaus; Fischer-Gödde, Mario; Taetz, Stephan; Böhnke, Mischa; Schmid-Beurmann, Hinrich; Münker, Carsten; Kleine, Thorsten; Srinivasan, Gopalan

    2017-09-01

    The long-lived 176Lu-176Hf and 147Sm-143Nd radioisotope systems are commonly used chronometers, but when applied to meteorites, they can reveal disturbances. Specifically, Lu-Hf isochrons commonly yield dates up to ∼300 Myr older than the solar system and varying initial 176Hf/177Hf values. We investigated this problem by attempting to construct mineral and whole rock isochrons for eucrites and angrites. Meteorites from different parent bodies exhibit similar disturbance features suggesting that a common process is responsible. Minerals scatter away from isochron regressions for both meteorite classes, with low-Hf phases such as plagioclase and olivine typically being most displaced above (or left of) reference isochrons. Relatively Hf-rich pyroxene is less disturbed but still to the point of steepening Lu-Hf errorchrons. Using our Lu-Hf and Sm-Nd data, we tested various Hf and Lu redistribution scenarios and found that decoupling of Lu/Hf from 176Hf/177Hf must postdate the accumulation of significant radiogenic 176Hf. Therefore early irradiation or diffusion cannot explain the excess 176Hf. Instead, disturbed meteorite isochrons are more likely caused by terrestrial weathering, contamination, or common laboratory procedures. The partial dissolution of phosphate minerals may predominantly remove rare earth elements including Lu, leaving relatively immobile and radiogenic Hf behind. Robust Lu-Hf (and improved Sm-Nd) meteorite geochronology will require the development of chemical or physical methods for removing unsupported radiogenic Hf and silicate-hosted terrestrial contaminants without disturbing parent-daughter ratios.

  2. 177Lu-DTPA-BIS-BIOTIN的制备及正常鼠体内生物分布%Preparation of 177Lu-DTPA-BIS-BIOTIN and Biodistribution Evaluation in Normal Mice

    Institute of Scientific and Technical Information of China (English)

    邓新荣; 杜进; 罗志福

    2010-01-01

    研究了DTPA-BIS-BIOTIN的177Lu标记方法,优化了标记条件,并进行了标记物在正常小鼠体内分布实验.在最佳标记条件下(DTPA-BIS-BIOTIN 25 μg,标记介质pH=4.5,80℃反应20 min),177Lu-DTPA-BIS-BIOTIN标记率大于99.0%,室温下放置96 h,标记物体外稳定性良好.正常小鼠体内分布实验结果表明,177Lu-DTPA-BIS-BIOTIN在血液中清除快,主要浓集于肝、脾和肾,经肾脏排泄.本研究为进一步采用177Lu-DTPA-BIS-BIOTIN进行肿瘤预定位显像及治疗研究提供了实验基础.

  3. Breaking the geometric magnetic frustration in controlled off-stoichiometric LuMn1+zO3+δ compounds.

    Science.gov (United States)

    Figueiras, F G; Karpinsky, D; Tavares, P B; Das, Soma; Leitão, J V; Brück, E H; Moreira, J Agostinho; Amaral, V S

    2016-05-11

    This study explores controlled off-stoichiometric LuMn1+zO3+δ (|z| LuMnO3 intrinsic hexagonal symmetry and ferroelectric properties. X-ray powder diffraction measurements evidenced a single phase P63cm structure. Thermo-gravimetric experiments show a narrow impact of oxygen vacancies while a distinguishable gas exchange at ∼700 K, a surprisingly lower temperature when compared to perovskite systems. A comparison of different nominal ceramics revealed pertinent structural and magnetic property variations owing to subtle self-doping effects. Deviations from the archetypal antiferromagnetic state were detected below ∼90 K suggesting local rearrangements of the nominal Mn(3+) ions matrix, breaking the ideal geometrical spin frustration, leading to a non-compensated magnetic structure.

  4. Role of the apical oxygen in RMnO3 (R = Ho and Lu) low temperature magneto-electric effect

    Science.gov (United States)

    Vermette, Jonathan; Jandl, Serge

    2012-02-01

    Multiferroic materials are promising candidates for new innovative devices, particularly in the field of memory storage. The strong coupling between magnetic ordering and ferroelectricity characterizing these compounds allows the modulation of the electric polarization (magnetic moment) with an external magnetic (electric) field. Hexagonal RMnO3 (Ho to Lu) compounds are type-I multiferroics in which ferroelectricity and magnetism have different sources giving a relative weak magneto-electric coupling with a large polarization. In this case ferroelectricity is induced at a relative high temperature (TC ˜ 800K) following a structural transition, while magnetic ordering of Mn^3+ and R^3+ occurs at lower temperatures (T LuMnO3 under applied magnetic field below THo = 5K. By comparing the renormalized force constants and the Born-effective charges, apical oxygen role in Ho^3+-Mn^3+ superexchange interaction is particularly underlined.

  5. Magnon Breakdown in a Two Dimensional Triangular Lattice Heisenberg Antiferromagnet of Multiferroic LuMnO3

    Science.gov (United States)

    Oh, Joosung; Le, Manh Duc; Jeong, Jaehong; Lee, Jung-hyun; Woo, Hyungje; Song, Wan-Young; Perring, T. G.; Buyers, W. J. L.; Cheong, S.-W.; Park, Je-Geun

    2013-12-01

    The breakdown of magnons, the quasiparticles of magnetic systems, has rarely been seen. By using an inelastic neutron scattering technique, we report the observation of spontaneous magnon decay in multiferroic LuMnO3, a simple two dimensional Heisenberg triangular lattice antiferromagnet, with large spin S=2. The origin of this rare phenomenon lies in the nonvanishing cubic interaction between magnons in the spin Hamiltonian arising from the noncollinear 120° spin structure. We observed all three key features of the nonlinear effects as theoretically predicted: a rotonlike minimum, a flat mode, and a linewidth broadening, in our inelastic neutron scattering measurements of single crystal LuMnO3. Our results show that quasiparticles in a system hitherto thought of as “classical” can indeed break down.

  6. Novel multiferroic state and ME enhancement by breaking the AFM frustration in LuMn1-xO3.

    Science.gov (United States)

    Figueiras, F G; Karpinsky, D; Tavares, P B; Gonçalves, J N; Yañez-Vilar, S; Moreira Dos Santos, A F; Franz, A; Tovar, M; Agostinho Moreira, J; Amaral, V S

    2017-01-04

    This study provides a comprehensive insight into the effects of controlled off-stoichiometry on the structural and multiferroic properties of the hexagonal manganite LuMn1-xO3+δ (x = 0.02; δ ∼ 0), supported by neutron powder diffraction measurements confirming single phase P63cm symmetry and evidencing a relevant ferromagnetic component, below TN ∼ 90 K, which breaks the archetypal geometrically frustrated antiferromagnetic state typically ascribed to LuMnO3. The perturbations in the triangular disposition of spins prompt an additional electric polarization contribution and a clear enhancement of the magnetoelectric coupling which are in good agreement with the results of first principles calculations. In addition, Raman spectroscopy, dielectric permittivity, pyroelectric current and magnetic measurements as a function of temperature point out the precursor effects of the magnetic phase transitions involving a strong coupling between spins, lattice and electric order, even above the Néel temperature.

  7. Topological phase, structural, electronic, thermodynamic and optical properties of XPtSb (X=Lu, Sc) compounds

    Science.gov (United States)

    Narimani, Mitra; Nourbakhsh, Zahra

    2017-03-01

    The electronic, thermodynamic and optical properties of XPtSb (X=Lu, Sc) half Heusler compounds are studied based on density functional theory. The calculations are carried out in the presence of spin orbit interaction. The exchange correlation part of total energy is calculated within local density approximation, generalized gradient approximation, Engel-Vosco generalized gradient approximation and modified Becke and Johnson exchange potential with the correlation potential of the generalized gradient approximation. The effect of pressure on the electron density of states and linear coefficient of the electronic specific heat is studied. Using the band structure calculations at different pressures, the band inversion strength and topological phase transition of these compounds are investigated. Some thermodynamic properties of XPtSb compounds by different thermal models using the non-equilibrium Gibbs function are studied and compared with experiment. Furthermore the effect of pressure on dielectric function of XPtSb (X=Lu, Sc) compounds is investigated.

  8. Magnon breakdown in a two dimensional triangular lattice Heisenberg antiferromagnet of multiferroic LuMnO3.

    Science.gov (United States)

    Oh, Joosung; Le, Manh Duc; Jeong, Jaehong; Lee, Jung-hyun; Woo, Hyungje; Song, Wan-Young; Perring, T G; Buyers, W J L; Cheong, S-W; Park, Je-Geun

    2013-12-20

    The breakdown of magnons, the quasiparticles of magnetic systems, has rarely been seen. By using an inelastic neutron scattering technique, we report the observation of spontaneous magnon decay in multiferroic LuMnO3, a simple two dimensional Heisenberg triangular lattice antiferromagnet, with large spin S=2. The origin of this rare phenomenon lies in the nonvanishing cubic interaction between magnons in the spin Hamiltonian arising from the noncollinear 120° spin structure. We observed all three key features of the nonlinear effects as theoretically predicted: a rotonlike minimum, a flat mode, and a linewidth broadening, in our inelastic neutron scattering measurements of single crystal LuMnO3. Our results show that quasiparticles in a system hitherto thought of as "classical" can indeed break down.

  9. Isomeric ratio measurements for the radiative neutron capture 176Lu(n ,γ ) at the LANL DANCE facility

    Science.gov (United States)

    Denis-Petit, D.; Roig, O.; Méot, V.; Morillon, B.; Romain, P.; Jandel, M.; Kawano, T.; Vieira, D. J.; Bond, E. M.; Bredeweg, T. A.; Couture, A. J.; Haight, R. C.; Keksis, A. L.; Rundberg, R. S.; Ullmann, J. L.

    2016-11-01

    The isomeric ratios for the neutron capture reaction 176Lu(n ,γ ) to the Jπ=5 /2- , 761.7 keV, T1 /2=32.8 ns and the Jπ=15 /2+ , 1356.9 keV, T1 /2=11.1 ns levels of 177Lu have been measured for the first time. The experiment was carried out with the Detector for Advanced Neutron Capture Experiments (DANCE) at the Los Alamos National Laboratory. Measured isomeric ratios are compared with talys calculations using different models for photon strength functions, level densities, and optical potentials. In order to reproduce the experimental γ -ray spectra, a low-energy resonance must be added in the photon strength function used in our Hauser-Feshbach calculations.

  10. Ce-doped LuAG single-crystal fibers grown from the melt for high-energy physics

    CERN Document Server

    Xu, X; Moretti, F; Pauwels, K; Lecoq, P; Auffray, E; Dujardin, C

    2014-01-01

    Under a stationary stable regime undoped and Ce-doped LuAG (Lu3Al5O12) single-crystal fibers were grown by a micro-pulling-down technique. The meniscus length corresponding to the equilibrium state was <200 mu m. Fluctuations in the fiber composition and pulling rate were found to have a significant effect on the properties of the fibers grown. A great improvement in the performance was found in samples containing low Ce concentrations (<= 0.1 at.\\%) and produced using pulling rates <0.5 mm min(-1). Under such conditions a good lateral surface fiber quality was obtained and light propagation was significantly improved. Conversely, a high Ce concentration and a high pulling rate resulted in a strong degradation of the fiber surface quality causing defects to appear and a decrease in light output. (C) 2014 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

  11. Analýza sportovního areálu vybranými metodami

    OpenAIRE

    Jelínek, Vojtěch

    2014-01-01

    Bakalářská práce se zabývá analýzou sportovního areálu U Hrocha, který má být dokončen v roce 2014. Obsahuje teoretická východiska, která jsou následně implementována do skutečné reality podniku, a to prostřednictvím PESTLE analýzy, Porterovy analýzy a SWOT analýzy. Závěrem je vyhodnocena situace a jsou navržena řešení pro optimalizaci chodu sportovního areálu. This bachelor´s thesis deals with analysis of the sports complex U Hrocha, which will be completed in 2014. It contains theoretica...

  12. 鲁迅救国思想流变探微%Research on Lu Xun's Thought of Saving Nation

    Institute of Scientific and Technical Information of China (English)

    杨坤

    2012-01-01

    Living in an era China was urgently in need of rescue,Lu Xun,as a patriot,naturally shouldered the burden of the nation rescue.From China to Japan,from Japan to China,on the issue of how to save the nation,Lu xun's experienced the thought transformation from saving the nation with science and technology,to saving the nation with literature and art,and finally to saving the nation with revolution.%生活在中国急需疗救的时代,作为爱国者的鲁迅,自然担起了救国的担子。从中国到日本,从日本到中国,对如何救国,鲁迅经历了从科技救国到文艺救国到革命救国的思想转变。

  13. Spectroscopic factor and proton formation probability for the d3/2 proton emitter 151mLu

    Directory of Open Access Journals (Sweden)

    F. Wang

    2017-07-01

    Full Text Available The quenching of the experimental spectroscopic factor for proton emission from the short-lived d3/2 isomeric state in 151mLu was a long-standing problem. In the present work, proton emission from this isomer has been reinvestigated in an experiment at the Accelerator Laboratory of the University of Jyväskylä. The proton-decay energy and half-life of this isomer were measured to be 1295(5 keV and 15.4(8 μs, respectively, in agreement with another recent study. These new experimental data can resolve the discrepancy in the spectroscopic factor calculated using the spherical WKB approximation. Using the R-matrix approach it is found that the proton formation probability indicates no significant hindrance for the proton decay of 151mLu.

  14. Influence of doping on the spin dynamics and magnetoelectric effect in hexagonal Y0.7Lu0.3MnO3

    Science.gov (United States)

    Tian, W.; Tan, Guotai; Liu, Liu; Zhang, Jinxing; Winn, Barry; Hong, Tao; Fernandez-Baca, J. A.; Zhang, Chenglin; Dai, Pengcheng

    2014-04-01

    We use inelastic neutron scattering and dielectric constant measurements to study the doping influence on the spin dynamics and magnetoelectric (ME) effect in hexagonalY0.7Lu0.3MnO3. In undoped YMnO3 and LuMnO3, the Mn trimerization distortion has been suggested to play a key role in determining the magnetic structure and the magnetoelectric effect. In Y0.7Lu0.3MnO3, at the antiferromagnetic zone center, we observed a much smaller Δ12≈0.52 meV gap (which is ˜2.5 meV for both YMnO3 and LuMnO3) that coincides with a weaker in-plane dielectric anomaly at TN; both can be attributed to a weaker Mn trimerization distortion in Y0.7Lu0.3MnO3 compared to YMnO3 and LuMnO3. The results provide strong evidence that the magnitude of ME coupling is linked to the strength of the trimerization distortion, suggesting the Mn trimerization is responsible for the ME effect in Y1-yLuyMnO3.

  15. Thermal properties measurement and laser operation of a new Yb: Gd0.68Lu0.32VO4 crystal.

    Science.gov (United States)

    Zhang, Huaijin; Yu, Yonggui; Cheng, Yan; Wang, Jiyang; Tao, Xutang; Jiang, Minhua; Xia, Huirui

    2008-07-21

    A new series mixed vanadate crystals, Yb:Gd(x)Lu(1-x)VO(4) (x=0.2, 0.35, 0.53, 0.68 and 0.84), were grown by the Czochralski method. The thermal conductivities of these crystals were measured from room temperature to 280?C, and the thermal conductivities of Yb:Gd(0.68)Lu(0.32)VO(4) at room temperature are 6.4 and 6.9 W m(-1)K(-1) along a- and c-axis, respectively. The material constants of Yb:Gd(x)Lu(1-x)VO(4) series crystals were estimated. The properties of Yb:Gd(x)Lu(1-x)VO(4) series crystals were compared with those of Yb:LuVO(4) and Yb:GdVO(4) crystals. Laser output power of 1.25 W at 1031 nm was obtained with a slope efficiency of 26% by use of diode pumping for Yb:Gd(0.68)Lu(0.32)VO(4) crystal.

  16. [Xi yuan lu (Records for Washing Away of Wrong Cases) and justice tests in the Republic of China in the context of western knowledge].

    Science.gov (United States)

    Long, Wei

    2014-09-01

    Xi yuan lu (Records for Washing Away of Wrong Cases) has become the important criterion and authority of the criminal justice tests in the proceedings of case and judicatory judgment, since it was issued royally and officially in the reign of Kangxi Emperor of the Qing Dynasty. However, the Xi yuan lu and its traditional tests was subjected to strong criticism after the introduction of modern science. Especially since the May 4(th) New Culture Movement, not only the theory in the Xi yuan lu had been met with incredulity and condemned sharply through western chemical tests by the intelligentsia, but also the traditional methods of justice tests based on the book was fully criticized. Though the Xi yuan lu has fallen down from the altar, the traditional methods in the book still were used in practice in China during 1930s--1940s because the scientific system of forensic medicine was not established yet. Xi yuan lu, though fallen yet not defeated, reveals its deep-rooted life. The modern fate of the Xi yuan lu was not only the direct result of different historical conversation in the different periods of modern time, but also a true picture of modern China.

  17. The challenges of treating paraganglioma patients with {sup 177}Lu-DOTATATE PRRT: Catecholamine crises, tumor lysis syndrome and the need for modification of treatment protocols

    Energy Technology Data Exchange (ETDEWEB)

    Makis, William; Mccann, Karey; Mcewan, Alexander J. B. [Dept. of Diagnostic Imaging, Cross Cancer Institute, Alberta (China)

    2015-09-15

    A high percentage of paragangliomas express somatostatin receptors that can be utilized for targeted radioisotope therapy. The aim of this study was to describe and discuss the challenges of treating these tumors with {sup 177}Lu-[DOTA0,Tyr3]octreotate (DOTATATE) radioisotope therapy using established protocols. Three paraganglioma patients were treated with 4–5 cycles of {sup 177}Lu-DOTATATE and were evaluated for side effects and response to therapy. Two of the three patients developed severe adverse reactions following their first {sup 177}Lu-DOTATATE treatment. One patient developed a catecholamine crisis and tumor lysis syndrome within hours of treatment, requiring intensive care unit (ICU) support, and another developed a catecholamine crisis 3 days after treatment, requiring hospitalization. The treatment protocols at our institution were subsequently modified by increasing the radioisotope infusion time from 15 to 30 min, as recommended in the literature, to 2–4 h and by reducing the administered dose of {sup 177}Lu-DOTATATE. Subsequent {sup 177}Lu-DOTATATE treatments utilizing the modified protocols were well tolerated, and response to therapy was achieved in all three patients, resulting in significantly improved quality of life. {sup 177}Lu-DOTATATE is an exciting new therapeutic option in the management of paragangliomas; however, current treatment protocols described in the literature may need to be modified by lengthening the infusion time and/or lowering the initial treatment dose to prevent or reduce the severity of adverse reactions.

  18. Inadequate prenatal care utilization and associated factors in São Luís, Brazil.

    Science.gov (United States)

    Bernardes, Ariane Cristina Ferreira; da Silva, Raimundo Antonio; Coimbra, Liberata Campos; Alves, Maria Teresa Seabra Soares de Britto; Queiroz, Rejane Christine de Sousa; Batista, Rosângela Fernandes Lucena; Bettiol, Heloisa; Barbieri, Marco Antônio; da Silva, Antônio Augusto Moura

    2014-08-10

    Over the last decades there has been a reduction of social inequalities in Brazil, as well as a strong expansion of health services, including prenatal care. The objective of the present study was to estimate the rate of inadequate prenatal care utilization and its associated factors in São Luís, Brazil, in 2010 and to determine whether there was a reduction of inequity in prenatal care use by comparing the present data to those obtained from a previous cohort started in 1997/98. Data from the BRISA (Brazilian birth cohort studies of Ribeirão Preto and São Luís) population-based cohort, which started in 2010 (5067 women), were used. The outcome variable was the inadequate utilization of prenatal care, classified according to the recommendations of the Brazilian Ministry of Health. The explanatory variables were organized into three hierarchical levels based on the Andersen's behavioral model of the use of health services: predisposing, enabling and need factors. Only 2.0% of the women did not attend at least one prenatal care visit. The rate of inadequate prenatal care utilization was 36.7%. Despite an improved adequacy of prenatal care use from 47.3% in 1997/98 to 58.2% in 2010, social inequality persisted: both low maternal schooling (prevalence ratio (PR) = 2.78; 95% confidence interval (95% CI) 2.23-3.47 for 0 to 4 years of study) and low family income, less than 0.5 monthly minimum wage per capita (PR = 1.37; 95% CI 1.22-1. 54), continued to be associated with higher rates of inadequate prenatal care utilization. Racial disparity regarding adequate utilization of prenatal services was detected, with black (PR = 1.19; 95% CI 1.04-1.36) and mulatto (PR = 1.14; 95% CI 1.02-1.26) women showing higher rates of inadequate use. On the other hand, women covered by the FHP - Family Health Program (PR = 0.92; 95% CI 0.85-0.98) showed a lower rate of inadequate prenatal care utilization. Despite strong expansion of health services and expressive improvements in

  19. Lu Xun and Bryusov%鲁迅与勃留索夫

    Institute of Scientific and Technical Information of China (English)

    李春林

    2015-01-01

    勃留索夫的"情境小说"和"面具化"叙述策略,在鲁迅小说中有相似之处.他们的许多作品都着力于展现处于非正常的情境或危机状态中的特定思想意识和情感,"对性格的描写让位于对情境的呈现";都使用了"双层次的第一人称"的叙说方式,创作了"小说中的小说",作家本人的思想与情怀掩藏在面具之后,使得作品具有了阐发的多义性和持续性,从而获得了更为久远的生命力.但鲁迅并未受有勃留索夫之明显影响.他的"情境小说"的创造,主要是他自己在多方面进行艺术探索的结果.甚至他的某些作品要比勃留索夫的一些创作更符合"情境小说"的本义.鲁迅与勃留索夫有着艺术上的某种同源关系,他们都对陀思妥耶夫斯基和爱伦·坡感兴趣.并受有影响.%Valery Bryusov is a Russian writer with great achievements in both fiction and poetry. Lu Xun paid great attention to him and his creation. In terms of fictional creation, they shared such things in common as unusual situations, specific ideology and emotions in crisis, the narrative mode of double-level first person. They created fiction within fiction, but Lu Xun was not obviously influenced by Bryusov. Their ideas were covered under the mask, and therefore their works have more vitality due to their diverse interpretations. The two writers, though far apart, have some homologous relations in their creative arts. For example, they were both interested in Dostoevsky and Allan Poe.

  20. Correlation consistent basis sets for lanthanides: The atoms La-Lu.

    Science.gov (United States)

    Lu, Qing; Peterson, Kirk A

    2016-08-07

    Using the 3rd-order Douglas-Kroll-Hess (DKH3) Hamiltonian, all-electron correlation consistent basis sets of double-, triple-, and quadruple-zeta quality have been developed for the lanthanide elements La through Lu. Basis sets designed for the recovery of valence correlation (defined here as 4f5s5p5d6s), cc-pVnZ-DK3, and outer-core correlation (valence + 4s4p4d), cc-pwCVnZ-DK3, are reported (n = D, T, and Q). Systematic convergence of both Hartree-Fock and correlation energies towards their respective complete basis set (CBS) limits are observed. Benchmark calculations of the first three ionization potentials (IPs) of La through Lu are reported at the DKH3 coupled cluster singles and doubles with perturbative triples, CCSD(T), level of theory, including effects of correlation down through the 4s electrons. Spin-orbit coupling is treated at the 2-component HF level. After extrapolation to the CBS limit, the average errors with respect to experiment were just 0.52, 1.14, and 4.24 kcal/mol for the 1st, 2nd, and 3rd IPs, respectively, compared to the average experimental uncertainties of 0.03, 1.78, and 2.65 kcal/mol, respectively. The new basis sets are also used in CCSD(T) benchmark calculations of the equilibrium geometries, atomization energies, and heats of formation for Gd2, GdF, and GdF3. Except for the equilibrium geometry and harmonic frequency of GdF, which are accurately known from experiment, all other calculated quantities represent significant improvements compared to the existing experimental quantities. With estimated uncertainties of about ±3 kcal/mol, the 0 K atomization energies (298 K heats of formation) are calculated to be (all in kcal/mol): 33.2 (160.1) for Gd2, 151.7 (-36.6) for GdF, and 447.1 (-295.2) for GdF3.

  1. Boats, cruises, planks and laddes: the Portuguese society under the intertextual perspective of Luís de Sttau Monteiro

    Directory of Open Access Journals (Sweden)

    Jaime dos Reis Sant'Anna

    2016-07-01

    Full Text Available The objective of this paper is to analyse Auto da barca do motor fora da borda (1966, by Luís de Sttau Monteiro, from the intertextual dialogue he does with Auto da barca do inferno (1517, by Gil Vicente. Boat and cruise are scenic signs used by authors to represent two historic moments in Por­tugal. However, in both instances, people who work for thrive the society cannot participate in your progress.

  2. Q-switched Ho:Lu2O3 laser at 2.12 μm.

    Science.gov (United States)

    Lamrini, Samir; Koopmann, Philipp; Scholle, Karsten; Fuhrberg, Peter

    2013-06-01

    We report on a Q-switched Ho:Lu2O3 laser resonantly pumped by a GaSb-based laser diode stack at 1.9 μm. The maximum output energy extracted from the compact plano-plano acousto-optically Q-switched resonator was 8 mJ at a 100 Hz pulse repetition rate, while the peak power was 40 kW. The laser wavelength was 2.124 μm.

  3. Therapeutic Efficacy with Treatment-related Toxicities of {sup 177}Lu-labeled Bombesin Derivative for the Peptide Receptor Radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Jae Cheong; Cho, Eun Ha; Lee, So Young [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    The gastrin-releasing peptide receptor (GRPR) has been shown to be overexpressed in many human tumours, including breast cancer, prostate cancer, small cell lung cancer, ovarian cancers, endometrial cancers, and gastrointestinal stromal tumors. In particular, GRPR expression is high in 83 % of invasive primary prostatic carcinomas. These results suggest that {sup 177}Lu-labeled bombesin derivative has promising characteristics as a novel nuclear medicine, especially for the treatment of GRPR over-expressing prostate tumors.

  4. Raman study of the antiferromagnetic phase transitions in hexagonal Y MnO3 and LuMnO3

    Science.gov (United States)

    Vermette, J.; Jandl, S.; Mukhin, A. A.; Ivanov, V. Yu; Balbashov, A.; Gospodinov, M. M.; Pinsard-Gaudart, L.

    2010-09-01

    The A1, E1 and E2 Raman active modes in hexagonal Y MnO3 and LuMnO3 single crystals are studied as a function of temperature and compared with previous measurements. In addition to anharmonicity, some phonon frequencies show below TN anomalous temperature dependences that reflect the atomic displacements while some other phonon frequencies are more sensitive to the spin-phonon coupling.

  5. 177Lu-Dendrimer Conjugated to Folate and Bombesin with Gold Nanoparticles in the Dendritic Cavity: A Potential Theranostic Radiopharmaceutical

    Directory of Open Access Journals (Sweden)

    Héctor Mendoza-Nava

    2016-01-01

    Full Text Available 177Lu-labeled nanoparticles conjugated to biomolecules have been proposed as a new class of theranostic radiopharmaceuticals. The aim of this research was to synthesize 177Lu-dendrimer(PAMAM-G4-folate-bombesin with gold nanoparticles (AuNPs in the dendritic cavity and to evaluate the radiopharmaceutical potential for targeted radiotherapy and the simultaneous detection of folate receptors (FRs and gastrin-releasing peptide receptors (GRPRs overexpressed in breast cancer cells. p-SCN-Benzyl-DOTA was conjugated in aqueous-basic medium to the dendrimer. The carboxylate groups of Lys1Lys3(DOTA-bombesin and folic acid were activated with HATU and also conjugated to the dendrimer. The conjugate was mixed with 1% HAuCl4 followed by the addition of NaBH4 and purified by ultrafiltration. Elemental analysis (EDS, particle size distribution (DLS, TEM analysis, UV-Vis, and infrared and fluorescence spectroscopies were performed. The conjugate was radiolabeled using 177LuCl3 or 68GaCl3 and analyzed by radio-HPLC. Studies confirmed the dendrimer functionalization with high radiochemical purity (>95%. Fluorescence results demonstrated that the presence of AuNPs in the dendritic cavity confers useful photophysical properties to the radiopharmaceutical for optical imaging. Preliminary binding studies in T47D breast cancer cells showed a specific cell uptake (41.15±2.72%. 177Lu-dendrimer(AuNP-folate-bombesin may be useful as an optical and nuclear imaging agent for breast tumors overexpressing GRPR and FRs, as well as for targeted radiotherapy.

  6. Skin dose saving of the staff in 90Y/177Lu peptide receptor radionuclide therapy with the automatic dose dispenser.

    Science.gov (United States)

    Fioroni, Federica; Grassi, Elisa; Giorgia, Cavatorta; Sara, Rubagotti; Piccagli, Vando; Filice, Angelina; Mostacci, Domiziano; Versari, Annibale; Iori, Mauro

    2016-10-01

    When handling Y-labelled and Lu-labelled radiopharmaceuticals, skin exposure is mainly due to β-particles. This study aimed to investigate the equivalent dose saving of the staff when changing from an essentially manual radiolabelling procedure to an automatic dose dispenser (ADD). The chemist and physician were asked to wear thermoluminescence dosimeters on their fingertips to evaluate the quantity of Hp(0.07) on the skin. Data collected were divided into two groups: before introducing ADD (no ADD) and after introducing ADD. For the chemist, the mean values (95th percentile) of Hp(0.07) for no ADD and ADD are 0.030 (0.099) and 0.019 (0.076) mSv/GBq, respectively, for Y, and 0.022 (0.037) and 0.007 (0.023) mSv/GBq, respectively, for Lu. The reduction for ADD was significant (t-test with Pisotopes. The relative differences before and after ADD collected for every finger were treated using the Wilcoxon test, proving a significantly higher reduction in extremity dose to each fingertip for Lu than for Y (Pmedical staff, the mean values of Hp(0.07) (95th percentile) for no ADD and ADD are 0.021 (0.0762) and 0.0143 (0.0565) mSv/GBq, respectively, for Y, and 0.0011 (0.00196) and 0.0009 (0.00263) mSv/GBq, respectively, for Lu. The t-test provided a P-value less than 0.05 for both isotopes, making the difference between ADD and no ADD significant. ADD positively affects the dose saving of the chemist in handling both isotopes. For the medical staff not directly involved with the introduction of the ADD system, the analysis shows a learning curve of the workers over a 5-year period. Specific devices and procedures allow staff skin dose to be limited.

  7. Energy transfer in Tb3+,Yb3+ codoped Lu2O3 near-infrared downconversion nanophosphors

    Institute of Scientific and Technical Information of China (English)

    LI Li; WEI Xiantao; CHEN Yonghu; GUO Changxin; YIN Min

    2012-01-01

    Tb3+ and Yb3+ codoped Lu2O3 nanophosphors were synthesized by the reverse-strike co-precipitation method.The obtained Lu2O3:Tb3+,Yb3+ nanophosphors were characterized by X-ray diffraction (XRD) and photoluminescence (PL) spectra.The XRD results showed that all the prepared nanophosphors could be readily indexed to pure cubic phase of Lu2O3 and indicated good crystallinity.The Tb3+→Yb3+ energy transfer mechanisms in the UV-blue region in Lu2O3 nanophosphors were investigated.The experimental results showed that the strong visible emission around 543 nm from Tb3+ (5D4→7F5) and near-infrared (NIR) emission around 973 nm from Yb3+ (2F5/2→2F7/2) of LuzO3:Tb3+,Yb3+ nanophosphors were observed under ultraviolet light excitation,respectively.Tb3+ could be effectively excited up to its 4f75d1 state and relaxed down to the 5D4 level,from which the energy was transferred cooperatively to two neighboring Yb3+.The Yb3+concentration dependent luminescent properties and lifetimes of both the visible and NIR emissions were also studied.The lifetime of the visible emission decreased with the increase of Yb3+ concentration,verifying the efficient energy transfer from the Tb3+to the Yb3+.Cooperative energy transfer (CET) from Tb3+ to Yb3+ was discussed as a possible mechanism for the near-infrared emission.When doped concentrations were 1 mol.% Tb3+ and 2 mol.% Yb3+,the intensity of NIR emission was the strongest.

  8. Sintering, Thermal Conductivity, Optical and Lasing Properties of Doped-Lu2O3 Fiberous Transparent Ceramics

    Science.gov (United States)

    2016-02-26

    convert to 60 nm Lu2O3 particles. The authors argued that the precipitation method led to well-dispersed nanopowders as compared to the hard -aggregated...Post- HIPing specimens which had remnant open porosity may have trapped compressed argon in what subsequently became closed pores. The ensuing...some specimens, e.g. the one exposed to a 1700◦C sintering soak temperature and no air anneals, opaque grey spheres were observed dispersed within other

  9. Long-term toxicity of [{sup 177}Lu-DOTA{sup 0},Tyr{sup 3}]octreotate in rats

    Energy Technology Data Exchange (ETDEWEB)

    Rolleman, Edgar J.; Krenning, Eric P.; Bernard, Bert F.; Visser, Monique de; Bijster, Magda; Jong, Marion de [Erasmus MC Rotterdam, Department of Nuclear Medicine, Rotterdam (Netherlands); Visser, Theo J. [Erasmus MC Rotterdam, Department of Internal Medicine, Rotterdam (Netherlands); Vermeij, Marcel [Erasmus MC Rotterdam, Department of Pathology, Rotterdam (Netherlands); Lindemans, Jan [Erasmus MC Rotterdam, Department of Clinical Chemistry, Rotterdam (Netherlands)

    2007-02-15

    Studies on peptide receptor radionuclide therapy (PRRT) using radiolabelled somatostatin analogues have shown promising results with regard to tumour control. The efficacy of PRRT is limited by uptake and retention in the proximal tubules of the kidney, which might lead to radiation nephropathy. We investigated the long-term renal toxicity after different doses of [{sup 177}Lu-DOTA{sup 0},Tyr{sup 3}]octreotate and the effects of dose fractionation and lysine co-injection in two tumour-bearing rat models. Significant renal toxicity was detected beyond 100 days after start of treatment as shown by elevated serum creatinine and proteinuria. Microscopically, tubules were strongly dilated with flat epithelium, containing protein cylinders. Creatinine levels rose significantly after 555 MBq [{sup 177}Lu-DOTA{sup 0},Tyr{sup 3}]octreotate, but were significantly lower after 278 MBq (single injection) or two weekly doses of 278 MBq. Renal damage scores were maximal after 555 MBq and significantly lower in the 278 and 2 x 278 MBq groups. Three doses of 185 MBq [{sup 177}Lu-DOTA{sup 0},Tyr{sup 3}]octreotate with intervals of a day, a week or a month significantly influenced serum creatinine (469{+-}18, 134{+-}70 and 65{+-}15 {mu}mol/l, respectively; p<0.001). Renal histological damage scores were not significantly influenced by dose fractionation. Lysine co-administration with three weekly treatments of 185 MBq significantly lowered serum creatinine and proteinuria. Injection of high doses of [{sup 177}Lu-DOTA{sup 0},Tyr{sup 3}]octreotate resulted in severe renal damage in rats as indicated by proteinuria, elevated serum creatinine and histological damage. This damage was dose dependent and became overt between 100 and 200 days after treatment. Dose fractionation had significant beneficial effects on kidney function. Also, lysine co-injection successfully prevented functional damage. (orig.)

  10. In situ simultaneous determination of trace elements,U-Pb and Lu-Hf isotopes in zircon and baddeleyite

    Institute of Scientific and Technical Information of China (English)

    XIE LieWen; ZHANG YanBin; ZHANG HuiHuang; SUN JingFeng; WU FuYuan

    2008-01-01

    This paper describes a combined method of simultaneously measuring U-Pb and Lu-Hf isotopes as well as trace elements in Phalaborwa baddeleyite and 91500, GJ-1, TEMORA-1 and SK10-2 zircons by means of Neptune MC-ICPMS and Agilent Q-ICPMS connected to a 193 nm excimer laser ablation system. Material ablated by laser was carried in different proportions into Q-ICPMS for U-Pb isotopic and trace elemental and MC-ICPMS for Lu-Hf isotopic compositions. Experiments indicate that different propor-tions of ablated material for the Q-ICPMS and MC-ICPMS (6∶4, 5∶5 and 4∶6 respectively) do not show any bias for the zircon/baddeleyite U-Pb age, Lu-Hf isotope and trace elemental compositions within ana-lytical errors. Using 40-60 μm spot size, the obtained U-Pb ages of Phalaborwa baddeleyite, 91500, GJ-1, TEMORA and SK10-2 zircons are 2065~15 (2σ, n=20), 1063±6 (2σ, n=19), 613±6 (2σ,=20), 416±5 (2σ, n=20) and 32.6±0.5 (2σ, n=20) Ma, respectively. The 176Hf/177Hf ratios are 0.281231±24 (2SD, n=20), 0.282310±35 (2SD, n=19), 0.282028±34 (2SD, n=20), 0.282687±34 (2SD, n=20) and 0.282752±53 (2SD, n=20), respectively. The obtained trace elemental compositions are identical to the reference values. Therefore, this kind of technique makes it possible to simultaneously obtain the U-Pb age, Lu-Hf iso-topes and trace elemental compositions of zircon and baddeleyite, which could be an important tool in solving problems in earth sciences.

  11. Distinct microRNA expression profiles in mouse renal cortical tissue after 177Lu-octreotate administration.

    Directory of Open Access Journals (Sweden)

    Emil Schüler

    Full Text Available The aim of this study was to investigate the variation of the miRNA expression levels in normal renal cortical tissue after 177Lu-octreotate administration, a radiopharmaceutical used for treatment of neuroendocrine cancers.Female BALB/c nude mice were i.v. injected with 1.3, 3.6, 14, 45, or 140 MBq 177Lu-octreotate, while control animals received saline. The animals were killed at 24 h after injection and total RNA, including miRNA, was extracted from the renal cortical tissue and hybridized to the Mouse miRNA Oligo chip 4plex to identify differentially regulated miRNAs between exposed and control samples.In total, 57 specific miRNAs were differentially regulated in the exposed renal cortical tissues with 1, 29, 21, 27, and 31 miRNAs identified per dose-level (0.13, 0.34, 1.3, 4.3, and 13 Gy, respectively. No miRNAs were commonly regulated at all dose levels. miR-194, miR-107, miR-3090, and miR-3077 were commonly regulated at 0.34, 1.3, 4.3, and 13 Gy. Strong effects on cellular mechanisms ranging from immune response to p53 signaling and cancer-related pathways were observed at the highest absorbed dose. Thirty-nine of the 57 differentially regulated miRNAs identified in the present study have previously been associated with response to ionizing radiation, indicating common radiation responsive pathways.In conclusion, the 177Lu-octreotate associated miRNA signatures were generally dose-specific, thereby illustrating transcriptional regulation of radiation responsive miRNAs. Taken together, these results imply the importance of miRNAs in early immunological responses in the kidneys following 177Lu-octreotate administration.

  12. Continuous wave channel waveguide lasers in Nd:LuVO4 fabricated by direct femtosecond laser writing.

    Science.gov (United States)

    Ren, Yingying; Dong, Ningning; Macdonald, John; Chen, Feng; Zhang, Huaijin; Kar, Ajoy K

    2012-01-30

    Buried channel waveguides in Nd:LuVOlaser writing with the double-line technique. The photoluminescence properties of the bulk materials were found to be well preserved within the waveguide core region. Continuous-wave laser oscillation at 1066.4 nm was observed from the waveguide under ~809 nm optical excitation, with the absorbed pump power at threshold and laser slope efficiency of 98 mW and 14%, respectively.

  13. Reversibility of La and Lu sorption onto smectites: Implications for the design of engineered barriers in deep geological repositories

    Energy Technology Data Exchange (ETDEWEB)

    Galunin, Evgeny [Departament de Quimica Analitica, Universitat de Barcelona, Marti i Franques 1-11, 08028 Barcelona (Spain); Alba, Maria D.; Aviles, Miguel A. [Instituto de Ciencia de Materiales de Sevilla, Consejo Superior de Investigaciones Cientificas - Universidad de Sevilla, Av. Americo Vespucio 49, 41092 Sevilla (Spain); Santos, Maria J. [Departamento de Quimica, Universidade Estadual de Londrina, Londrina, PR, 86051-990 (Brazil); Vidal, Miquel, E-mail: miquel.vidal@ub.edu [Departament de Quimica Analitica, Universitat de Barcelona, Marti i Franques 1-11, 08028 Barcelona (Spain)

    2009-12-30

    The sorption reversibility of La and Lu (considered as actinide analogues) onto a set of smectites (bentonite FEBEX; hectorite, HEC; MX80; saponite, SAP; Otay montmorillonite, SCa-3; and Texas montmorillonite, STx-1) was studied to estimate actinide retention by smectites that are candidates for use as engineered barriers in deep geological repositories. The sorption distribution coefficients (K{sub d}) and the reversibility parameters (desorption distribution coefficients (K{sub d,des}), adjusted distribution coefficients (K{sub d,adj}), and desorption rates (R{sub des})) were determined from batch tests in two ionic media: deionized water and Ca 0.02 mol L{sup -1}. The latter simulates possible conditions due to the presence of concrete leachates. The results varied greatly depending on the ionic medium, the lanthanide concentration and the clay structure. The high values of K{sub d,des} obtained (up to 1.1 x 10{sup 5} and 9.2 x 10{sup 4} L kg{sup -1} for La and Lu in water, and 2.8 x 10{sup 4} and 4.1 x 10{sup 4} L kg{sup -1} for La and Lu in the Ca medium) indicate the suitability of the tested smectites for lanthanide (and therefore, actinide) retention. Based on all the data, SCa-3, HEC and FEBEX clays are considered the best choices for water environments, whereas in Ca environments the suitable clays depended on the lanthanide considered.

  14. Therapeutic Efficacy Observation on‘Setting F ire on the Mountain’ Manipulation by Lu Shou-yan for Cervical Radiculopathy

    Institute of Scientific and Technical Information of China (English)

    Sun Yi-jun; Wu Yao-chi; Zhang Jun-feng; Li Yan; Wang Ying

    2014-01-01

    Objective:To observe the clinical effect of‘setting fire on the mountain’ manipulation by Lu Shou-yan for cervical radiculopathy as well as the infrared thermographic changes of the cervical area before and after treatment. Methods:A total of 120 eligible cases with cervical radiculopathy were randomly allocated into an observation group and a control group, 60 in each group. Cases in the observation group were treated with Lu Shou-yan’s ‘setting fire on the mountain’ manipulation, whereas cases in the control group were treated with even reinforcing-reducing manipulation. After two courses of treatment, the infrared thermographic changes and overall therapeutic efficacies in the two groups were compared. Results: The recovery rate and total effective rate in the observation group were 68.3%and 98.3%respectively, versus 28.3%and 81.7%in the control group, showing statistical differences in recovery rate and total effective rate (both P Conclusion:‘Setting fire on the mountain’ manipulation by Lu Shou-yan is better than even reinforcing-reducing manipulation for cervical radiculopathy.

  15. Muslim Selbstverständnis: Ahmet Davutoğlu Answers Husserl’s Crisis of European Sciences

    Directory of Open Access Journals (Sweden)

    SCOTT MORRISON

    2014-06-01

    Full Text Available In formulating his understanding of Islamic history, thought and politics, the Turkish Muslim thinker Ahmet Davutoğlu adopts the German philosopher Edmund Husserl’s formulation of phenomenology – or, philosophy of consciousness. Both Husserl and Davutoğlu perceive a crisis in humanity and identify its causes in scientism and logical positivism, against which they develop their respective phenomenological alternatives. This article places in parallel Husserl’s stylised history of Western thought and Weltanschauung method with that of Davutoğlu’s Muslim worldview, in order to illuminate the latter’s putatively comprehensive interpretation of Islam, diagnosis of the ills of secularism, modernisation, and crisis of values he finds in Muslim societies; and his prescribed treatment for those ills: the privileging of ontology over epistemology, and the full unfolding of core theological concepts of revelation, monotheism, and prophecy. Davutoğlu seeks to reconcile tensions and disputes within Islamic intellectual traditions concerning the nature of God and God’s attributes, and the tension between mysticism and rationalism, and the historical and the atemporal. In summary, Davutoğlu’s intervention in Islamic traditions is interesting in the effort it makes to appropriate elements of both Husserl and GWF Hegel for the purpose of reconciling a phenomenological reading of Islam with established Islamic authorities and commitments.

  16. Distribution coefficients of 60 elements on TODGA resin: application to Ca, Lu, Hf, U and Th isotope geochemistry.

    Science.gov (United States)

    Pourmand, Ali; Dauphas, Nicolas

    2010-05-15

    Batch equilibration experiments are conducted to measure the distribution coefficients (K(d)) of a large number of elements in nitric, nitric plus hydrofluoric, and hydrochloric acids on Eichrom TODGA extraction chromatography resin. The K(d)s are used to devise a multi-element extraction scheme for high-precision elemental and isotopic analyses of Ca, Hf, Lu, Th and U in geological materials, using high-purity lithium metaborate (LiBO(2)) flux fusion that allows rapid digestion of even the most refractory materials. The fusion melt, dissolved in nitric acid, is directly loaded to a TODGA cartridge on a vacuum chamber for elemental separation. An Ln-Spec cartridge is used in tandem with TODGA for Lu purification. The entire procedure, from flux digestion to preparation for isotopic analysis, can be completed in a day. The accuracy of the proposed technique is tested by measuring the concentrations of Ca (standard bracketing), Hf, Lu, Th and U (isotope dilution), and the isotopic composition of Hf in geostandards (USNM3529, BCR-2, BHVO-1, AGV-1 and AGV-2). All measurements are in excellent agreement with recommended literature values, demonstrating the effectiveness of the proposed analytical procedure and the versatility of TODGA resin.

  17. First-principles studies of magnetoelectric coupling in hexagonal LuFeO3 under applied electric fields

    Science.gov (United States)

    Zhang, Yubo; Wang, Hongwei; Dhuvad, Pratikkumar; Xu, Xiaoshan; Stengel, Massimiliano; Wu, Xifan

    The recently stabilized hexagonal LuFeO3 thin-film provides an opportunity in realizing the magnetoelectric coupling in multiferroic materials, in which the weak ferromagnetism due to Dzyaloshinskii-Moriya interaction was found to be closely associated with the trimerization (K3) mode. Here, we performed first-principles calculations in hexagonal LuFeO3 and studied the variations of weak ferromagnetic moment under applied electric fields. It is found that the weak ferromagnetism is a property that can be directly tuned by the external electric fields. As an improper ferroelectric material, such a magnetoelectric coupling is realized by the strong interaction between the trimerization mode and ferroelectric mode. Under the electric field poling, ferroelectric mode will respond. A change in ferroelectric distortion will in turn affect the amplitude of trimerization mode, and therefore, the weak ferromagnetism. Interestingly, the magnetoelectric coupling in LuFeO3 shows a strong nonlinear behavior originating again from the coupling between the trimerization and ferroelectric modes due to its improper nature.

  18. Nanocrystalline lanthanide-doped Lu3Ga5O12 garnets: interesting materials for light-emitting devices.

    Science.gov (United States)

    Venkatramu, V; Giarola, M; Mariotto, G; Enzo, S; Polizzi, S; Jayasankar, C K; Piccinelli, F; Bettinelli, M; Speghini, A

    2010-04-30

    Nanocrystalline Lu(3)Ga(5)O(12), with average particle sizes of 40 nm, doped with a wide variety of luminescent trivalent lanthanide ions have been prepared using a sol-gel technique. The structural and morphological properties of the powders have been investigated by x-ray powder diffraction, high resolution transmission electron microscopy and Raman spectroscopy. Structural data have been refined and are presented for Pr(3+), Eu(3+), Gd(3+), Ho(3+), Er(3+) and Tm(3+) dopants, while room temperature excited luminescence spectra and emission decay curves of Eu(3+)-, Tm(3+)- and Ho(3+)-doped Lu(3)Ga(5)O(12) nanocrystals have been measured and are discussed. The Eu(3+) emission spectrum shows typical bands due to 5D(0)-->7F(J) (J = 0, 1, 2, 3, 4) transitions and the broadening of these emission bands with the non-exponential behaviour of the decay curves indicates the presence of structural disorder around the lanthanide ions. Lanthanide-doped nanocrystalline Lu(3)Ga(5)O(12) materials show better luminescence intensities compared to Y(2)O(3), Gd(3)Ga(5)O(12) and Y(3)Al(5)O(12) nanocrystalline hosts. Moreover, the upconversion emission intensity in the blue-green region for the Tm(3+)- and Ho(3+)-doped samples shows a significant increase upon 647.5 nm excitation with respect to other common oxide hosts doped with the same lanthanide ions.

  19. Study of interfaces and band offsets in TiN/amorphous LaLuO3 gate stacks

    KAUST Repository

    Mitrovic, Ivona Z.

    2011-07-01

    TiN/LaLuO3 (LLO) gate stacks formed by molecular beam deposition have been investigated by X-ray photoelectron spectroscopy, medium energy ion scattering, spectroscopic ellipsometry, scanning transmission electron microscopy, electron energy loss spectroscopy and atomic force microscopy. The results indicate an amorphous structure for deposited LLO films. The band offset between the Fermi level of TiN and valence band of LLO is estimated to be 2.65 ± 0.05 eV. A weaker La-O-Lu bond and a prominent Ti2p sub-peak which relates to Ti bond to interstitial oxygen have been identified for an ultra-thin 1.7 nm TiN/3 nm LLO gate stack. The angle-dependent XPS analysis of Si2s spectra as well as shifts of La4d, La3d and Lu4d core levels suggests a silicate-type with Si-rich SiOx LLO/Si interface. Symmetrical valence and conduction band offsets for LLO to Si of 2.2 eV and the bandgap of 5.5 ± 0.1 eV have been derived from the measurements. The band alignment for ultra-thin TiN/LLO gate stack is affected by structural changes. Copyright © 2011 Published by Elsevier B.V. All rights reserved.

  20. Eu3+ doped K-Lu-F system optical materials:controlling synthesis, phase evolution, and optical properties

    Institute of Scientific and Technical Information of China (English)

    谢安; 刘小磊; 熊禹诚

    2015-01-01

    Using a hydrothermal method, by adjusting the reactant ratios, the hydrothermal temperatures, the hydrothermal time, and the pH values of prepared solutions, 1 mol.% Eu3+ doped K-Lu-F system optical materials were synthesized under control. For com-parison, the sample was also synthesized by a co-precipitation method. The X-ray diffraction (XRD) results suggested that the final crystalline phases had great relations with the hydrothermal synthesis conditions. The field emission scanning electron microscopy (FE-SEM) images and the energy-dispersive spectroscopy (EDS) patterns indicated that the morphologies and the components of some representative samples also varied with the synthesis conditions. Eu3+, acting as a probe, exhibited different optical proper-ties in the K-Lu-F system optical materials, which also indirectly proved the phase evolution of the final products. The results sug-gested that there were many crystalline phases with different symmetry in the K-Lu-F system. They would be good host matrices for the emitters.