Investigation on Er{sup 3+}/Ho{sup 3+} co-doped silicate glass for ~2 µm fiber lasers

Energy Technology Data Exchange (ETDEWEB)

Liu, Xueqiang; Huang, Feifei; Cheng, Jimeng; Fan, Xiaokang; Gao, Song [Key Laboratory of Materials for High Power Laser, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800 (China); Graduate School of Chinese Academy of Science, Beijing 100039 (China); Zhang, Junjie [College of Materials Science and Technology, China Jiliang University, Hangzhou 310018 (China); Hu, Lili [Key Laboratory of Materials for High Power Laser, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800 (China); Chen, Danping, E-mail: dpchen2008@aliyun.com [Key Laboratory of Materials for High Power Laser, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800 (China)

2015-06-15

A stable Er{sup 3+}/Ho{sup 3+} co-doped lead silicate glass is developed. Luminescent properties are recorded under pumping with 808 and 1550 nm lasers. Energy-transfer mechanism and efficiency are analyzed. Energy-transfer efficiency from Er{sup 3+}:{sup 4}I{sub 13/2} to Ho{sup 3+}:{sup 5}I{sub 7} reaches 93.8% at 3 mol% Ho{sub 2}O{sub 3} doping concentration. Strong luminescence is detected when pumped at 1550 nm because of efficient energy transfer from Er{sup 3+}:{sup 4}I{sub 13/2} to Ho{sup 3+}:{sup 5}I{sub 7}. Peak gain coefficient at 2056 nm is detected as 1.62 cm{sup −1}. The excellent luminescent property and high stability indicate that Er{sup 3+}/Ho{sup 3+} co-doped lead silicate glass can be applied in 2 µm fiber lasers. - Highlights: • Er{sup 3+}/Ho{sup 3+} co-doped silicate glasses with high stability are prepared. • Strong luminescence is detected under pump of 1550 nm lasers owing to efficient energy transfer from Er{sup 3+} to Ho{sup 3+}. • Transfer efficiency is calculated to be 93.8% when Ho{sub 2}O{sub 3} doping concentration is up to 3 mol%. • Gain coefficient peaks at 2056 nm to be 1.62 cm{sup −1}.

Enhancement of red upconversion emission of cubic phase NaLuF{sub 4}: Yb{sup 3+}/Ho{sup 3+}/Ce{sup 3+} nanocrystals

Energy Technology Data Exchange (ETDEWEB)

Gao, Wei, E-mail: gaowei@xupt.edu.com; Dong, Jun, E-mail: dongjun@xupt.edu.cn; Liu, Jihong; Yan, Xuewen

2016-08-15

Highlights: • The upconversion emission of Ho{sup 3+} ions was tuned from green to red. • The upconversion mechanism of Ho{sup 3+} ions was discussed based on emission spectrum. • The conversion efficiency between Ho{sup 3+} and Ce{sup 3+} were studied and calculated. - Abstract: The red upconversion emission of lanthanide-doped fluoride nanocrystals have great potential applications in color display and anticounterfeiting applications, especially for biological imaging and biomedical. In this work, a significant enhancement of red upconversion emission of Ho{sup 3+} ions was successfully obtained in the cubic phase NaLuF{sub 4} nanocrystals through codoping Ce{sup 3+} ions under NIR 980 nm excitation. The ratio of red-to-green emission of Ho{sup 3+} ions was enhanced about 10-fold, which is due to two efficient cross relaxation processes derived from Ho{sup 3+} and Ce{sup 3+} ions promoted the red emission and quenched the green emission. The upconversion emission and luminescent colors of NaLuF{sub 4}: Yb{sup 3+}/Ho{sup 3+} nanocrystals were carefully investigated by a confocal microscopy setup. The possible upconversion emission mechanism and conversion efficiency of cross relaxation between Ho{sup 3+} and Ce{sup 3+} ions were discussed in detail. The current study suggests that strong red emission of NaLuF{sub 4}: Yb{sup 3+}/Ho{sup 3+}/Ce{sup 3+} nanomaterials can be used for color display and anticounterfeiting techniques.

Synthesis of novel branched β-NaLuF4: Yb/Er upconversion luminescence material and investigation of its optical properties

Science.gov (United States)

Ding, Yanli; Yang, Tonghui; Yin, Naiqiang; Shu, Fangjie; Zhao, Ying; Zhang, Xiaodan

2018-05-01

Branched β-NaLuF4: Yb/Er was synthesized using a simple hydrothermal method by controlling the NaF/Ln molar ratio. In contrast to the β-NaYF4: Yb/Er hexagonal disks, the branched β-NaLuF4: Yb/Er has stronger emission intensity. The integrated intensities of green and red emission bands were as 6.2 and 3.3 times as that of NaYF4, respectively. The branched β-NaLuF4: Yb/Er has the smaller unit cell volume, the higher absorption intensity around 980 nm and the lower crystal field symmetry than NaYF4, which made a significant contribution to the stronger upconversion (UC) fluorescence emissions. The results indicate that the branched β-NaLuF4: Yb/Er is an excellent UC luminescence material. The current research has a great potential in improving near-infrared conversion efficiency of solar cells.

Crystal growth and scintillation properties of Er-doped Lu{sub 3}Al{sub 5}O{sub 12} single crystals

Energy Technology Data Exchange (ETDEWEB)

Sugiyama, Makoto, E-mail: makoto.sugiyama@imr.tohoku.ac.jp [Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Fujimoto, Yutaka [Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Yanagida, Takayuki [New Industry Creation Hatchery Center (NICHe), Tohoku University, 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); Totsuka, Daisuke [Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Nihon Kessho Kogaku Co. Ltd., 810-5 Nobe-cho Tatebayashi Gunma (Japan); Kurosawa, Shunsuke; Futami, Yoshisuke; Yokota, Yuui; Chani, Valery [Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Yoshikawa, Akira [Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); New Industry Creation Hatchery Center (NICHe), Tohoku University, 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan)

2012-02-01

Er-doped Lu{sub 3}Al{sub 5}O{sub 12} (Er:LuAG) single crystalline scintillators with different Er concentrations of 0.1, 0.5, 1, and 3% were grown by the micro-pulling-down ({mu}-PD) method. The grown crystals were composed of single-phase material, as demonstrated by powder X-ray diffraction (XRD). The radioluminescence spectra measured under {sup 241}Am {alpha}-ray excitation indicated host emission at approximately 350 nm and Er{sup 3+} 4f-4f emissions. According to the pulse height spectra recorded under {gamma}-ray irradiation, the 0.5% Er:LuAG exhibited the highest peak channel among the samples. The {gamma}-ray excited decay time profiles were well fitted by the two-component exponential approximation (0.8 {mu}s and 6-10 {mu}s).

Metodika stanovení velikosti detekovaného signálu v EREM

OpenAIRE

Potoma, Jaroslav

2010-01-01

Předkládaná práce se zabývá problematikou environmentální rastrovací elektronové mikroskopie (EREM) a detekcí signálních elektronů pomocí ionizačního detektoru.Hlavní náplní této práce je porovnání osciloskopické metody stanovení velikosti signálu s metodou vyhodnocování velikosti signálu z úrovně šedi ze snímků standartních vzorků. Vyhodnocení výhod a nevýhod obou metod. This work deals with problematics of enviromental scanning electron microscopy and detection of signal electrons by ion...

Effective tuning of the ratio of red to green emission of Ho{sup 3+} ions in single LiLuF{sub 4} microparticle via codoping Ce{sup 3+} ions

Energy Technology Data Exchange (ETDEWEB)

Gao, Wei, E-mail: gaowei@xupt.edu.cn; Dong, Jun; Liu, Jihong; Yan, Xuewen

2016-09-15

Yb{sup 3+}/Ho{sup 3+} codoped LiLuF{sub 4} microparticles have been successfully prepared via a facile hydrothermal method. The crystal phase and morphology of LiLuF{sub 4} microparticles were inspected by x-ray diffraction and scanning electron microscope, respectively. The upconversion emission of single LiLuF{sub 4}: Yb{sup 3+}/Ho{sup 3+} microparticle was carefully studied by a confocal microscopy setup under NIR 980 nm excitation. With the increase of Ce{sup 3+} ion concentrations of 12%, the ratio of red to green emission of the Ho{sup 3+} ions of single LiLuF{sub 4} microparticle was boosted about 17-fold, and the output colors were tuned from green to red, which is due to the two efficient cross-relaxation between Ho{sup 3+} and Ce{sup 3+} ions enhances the red and suppresses the green in the emission processes. To investigate the optical properties of the single microparticle or nanoparticle through the confocal microscopy setup can effectively avoid the influence of surrounding particle or environment, and could provide more precise information for better exploring the emission mechanisms of rare earth ions. The tunable upconversion emission of Ho{sup 3+} in single LiLuF{sub 4} microparticle in this work will have great potential applications in the micro optoelectronic devices and color display applications. - Highlights: • The optical properties of the single LiLuF4: Yb3+/Ho3+/Ce3+ microparticle were studied. • The output colors of single LiLuF4 microparticle were tuned from green to red. • The upconversion mechanisms between Ho3+ and Ce3+ ions were discussed based on emission spectrum.

Cobalt-related features of spectral and magnetic properties of RNi4Co (R=Ho, Er)

International Nuclear Information System (INIS)

Lukoyanov, A.V.; Knyazev, Yu.V.; Kuz‘min, Yu.I.; Kuchin, A.G.

2014-01-01

In this paper we investigate spectral and magnetic properties of RNi 4 Co (R=Ho, Er) intermetallics to reveal the features associated with the presence of Co substituting ion in comparison with the parent HoNi 5 and ErNi 5 compounds. Our ab initio LSDA+U calculations show that in the electronic structure Co states are strongly manifested near the Fermi energy for the case of Co in 2c position, while Co in 3g position results only in weak changes of the total DOS curve. Theoretical optical conductivity calculated assuming Co equally redistributed among 2c or 3g positions agrees well with the experimental optical conductivity. Cobalt ion in RNi 4 Co (R=Ho, Er) is characterized by magnetic moment of 1μ B that increases exchange interaction in the 3d sublattice by several times that contributes to the growth of Curie temperature in comparison with the parent compounds. - Highlights: • Electronic structure of RNi4Co (R=Ho, Er) is calculated in LSDA+U. • Cobalt ion is considered in 2c or 3g position and compared. • Experimental optical conductivity is interpreted based on the calculated one

Nanosecond Tm:Y2O3 ceramic laser passively Q-switched by a Ho:LuAG ceramic

Science.gov (United States)

Wang, Hui; Huang, Haitao; Wang, Shiqiang; Shen, Deyuan

2018-02-01

A passively Q-switched 2.05-μm Tm:Y2O3 ceramic laser, employing Ho:LuAG ceramic as a saturable absorber, was demonstrated for the first time. Under the absorbed pump power of 20.5 W, a maximum output power of 497 mW was obtained. Pulses with a minimum pulse width of 642 ns under the repetition rate of 33 kHz were achieved. Our works validate that Ho-doped materials have good potential for passive Q-switching of Tm-doped lasers at 2-μm wavelength region.

Cobalt-related features of spectral and magnetic properties of RNi{sub 4}Co (R=Ho, Er)

Energy Technology Data Exchange (ETDEWEB)

Lukoyanov, A.V., E-mail: lukoyanov@imp.uran.ru [Institute of Metal Physics, Russian Academy of Sciences–Ural Branch, 620990 Yekaterinburg (Russian Federation); Ural Federal University, 620002 Yekaterinburg (Russian Federation); Knyazev, Yu.V.; Kuz‘min, Yu.I.; Kuchin, A.G. [Institute of Metal Physics, Russian Academy of Sciences–Ural Branch, 620990 Yekaterinburg (Russian Federation)

2014-11-15

In this paper we investigate spectral and magnetic properties of RNi{sub 4}Co (R=Ho, Er) intermetallics to reveal the features associated with the presence of Co substituting ion in comparison with the parent HoNi{sub 5} and ErNi{sub 5} compounds. Our ab initio LSDA+U calculations show that in the electronic structure Co states are strongly manifested near the Fermi energy for the case of Co in 2c position, while Co in 3g position results only in weak changes of the total DOS curve. Theoretical optical conductivity calculated assuming Co equally redistributed among 2c or 3g positions agrees well with the experimental optical conductivity. Cobalt ion in RNi{sub 4}Co (R=Ho, Er) is characterized by magnetic moment of 1μ{sub B} that increases exchange interaction in the 3d sublattice by several times that contributes to the growth of Curie temperature in comparison with the parent compounds. - Highlights: • Electronic structure of RNi4Co (R=Ho, Er) is calculated in LSDA+U. • Cobalt ion is considered in 2c or 3g position and compared. • Experimental optical conductivity is interpreted based on the calculated one.

Synthesis, Tunable Multicolor Output, and High Pure Red Upconversion Emission of Lanthanide-Doped Lu2O3 Nanosheets

Directory of Open Access Journals (Sweden)

Lingzhen Yin

2013-01-01

Full Text Available Yb3+ and Ln3+ (Ln = Er, Ho codoped Lu2O3 square nanocubic sheets were successfully synthesized via a facile hydrothermal method followed by a subsequent dehydration process. The crystal phase, morphology, and composition of hydroxide precursors and target oxides were characterized by X-ray diffraction (XRD, field emission scanning electron microscope (FE-SEM, and energy-dispersive X-ray spectroscope (EDS. Results present the as-prepared Lu2O3 crystallized in cubic phase, and the monodispersed square nanosheets were maintained both in hydroxide and oxides. Moreover, under 980 nm laser diode (LD excitation, multicolor output from red to yellow was realized by codoped different lanthanide ions in Lu2O3. It is noteworthy that high pure strong red upconversion emission with red to green ratio of 443.3 of Er-containing nanocrystals was obtained, which is beneficial for in vivo optical bioimaging.

Hydrogen induced structural and magnetic transformations in magnetic regenerator materials ErNi n (n=1, 2) and HoCu2

International Nuclear Information System (INIS)

Wang Dong; Li Yanli; Long Yi; Ye Rongchang; Chang Yongqin; Wan Farong

2007-01-01

The effect of hydrogenation on the structures and magnetic properties of magnetic regenerators HoCu 2 (CeCu 2 -type), ErNi 2 (MgCu 2 -type) and ErNi (FeB-type) has been investigated. All these compounds can form crystalline hydrides which remain in the structure of the original compound. In the case of ErNi 2 , hydrogenation induces volume expansion up to 13% compared with the parent compound. The magnetic moment and the Curie temperature of the crystalline hydrides decreases as the hydrogen content increases. In the case of ErNi and HoCu 2 , there is a little change in the lattice parameters and magnetic properties of the crystalline hydrides compared with original compounds. Amorphous hydrides are also observed after the hydrogenation of ErNi 2 and HoCu 2 compounds

em cristais de Ho:YLF e Er:YLF na região de 3m

Directory of Open Access Journals (Sweden)

Fábio Henrique Jagosich

2006-01-01

Full Text Available In this work, the deactivation energy transfer mechanisms of 4I13/2 of Er3+ and 5I7 of Ho3+ levels in crystals of LiYF4 (YLF co-doped with Nd3+, Tb3+ and Eu3+ are studied. It was determined the best combination with deactivator ions, capable to maximize the laser gain in the middle of the Ho3+ in 2.9 micrometers (mm and the Er3+ in 2.75 mm operation. The results showed that the Tb3+ and Eu3+ are the best deactivators to the Ho3+ laser operation, while for the Ho3+ laser operation, the best ion deactivator is the Nd3+. The energy transfer characterizations were carried out using the Förster-Dexter method, which consists in the determination of the interaction critic ray, to start from the integral superposition of the absorption cross section spectrum and the involved ions emission.

Protectin DX suppresses hepatic gluconeogenesis through AMPK-HO-1-mediated inhibition of ER stress.

Science.gov (United States)

Jung, Tae Woo; Kim, Hyung-Chun; Abd El-Aty, A M; Jeong, Ji Hoon

2017-06-01

Several studies have shown that protectins, which are ω-3 fatty acid-derived proresolution mediators, may improve insulin resistance. Recently, protectin DX (PDX) was documented to attenuate insulin resistance by stimulating IL-6 expression in skeletal muscle, thereby regulating hepatic gluconeogenesis. These findings made us investigate the direct effects of PDX on hepatic glucose metabolism in the context of diabetes. In the current study, we show that PDX regulates hepatic gluconeogenesis in a manner distinct from its indirect glucoregulatory activity via IL-6. We found that PDX stimulated AMP-activated protein kinase (AMPK) phosphorylation, thereby inducing heme oxygenase 1 (HO-1) expression. This induction blocked hepatic gluconeogenesis by suppressing endoplasmic reticulum (ER) stress in hepatocytes under hyperlipidemic conditions. These effects were significantly dampened by silencing AMPK or HO-1 expression with small interfering RNA (siRNA). We also demonstrated that administration of PDX to high fat diet (HFD)-fed mice resulted in increased hepatic AMPK phosphorylation and HO-1 expression, whereas hepatic ER stress was substantially attenuated. Furthermore, PDX treatment suppressed the expression of gluconeogenic genes, thereby decreasing blood glucose levels in HFD-fed mice. In conclusion, our findings suggest that PDX inhibits hepatic gluconeogenesis via AMPK-HO-1-dependent suppression of ER stress. Thus, PDX may be an effective therapeutic target for the treatment of insulin resistance and type 2 diabetes through the regulation of hepatic gluconeogenesis. Copyright © 2017 Elsevier Inc. All rights reserved.

Crystalline electric fields and magnetic properties of single-crystalline RNiC2 compounds R=Ho, Er and Tm

International Nuclear Information System (INIS)

Koshikawa, Y.; Onodera, H.; Kosaka, M.; Yamauchi, H.; Ohashi, M.; Yamaguchi, Y.

1997-01-01

Magnetometric investigations were performed on single-crystalline HoNiC 2 , ErNiC 2 and TmNiC 2 compounds. Susceptibility of HoNiC 2 shows no anomaly around T N , but a clear cusp appears at T t =2.9 K. Magnetization curves reveal that the anisotropy is relatively weak and that the Ho moments align not along any crystallographic axis. In addition to T N =8.5 K of ErNiC 2 , a new order-order transition at T t =3.6 K has been found. Although the Er moments align along the a-axis between T t and T N , it seems certain that the small moment-components along the b- and c-axes come into existence below T t . TmNiC 2 with T N =5.5 K has a strong uniaxial anisotropy along the a-axis. These results are discussed on the basis of competitions between the magnetic interactions and the crystal field effect which changes anomalously by the replacement of rare earth element. It has been found that the drastic change of crystal field occurs between HoNiC 2 and ErNiC 2 without any corresponding structural change. (orig.)

The normal and inverse magnetocaloric effect in RCu2 (R=Tb, Dy, Ho, Er) compounds

International Nuclear Information System (INIS)

Zheng, X.Q.; Xu, Z.Y.; Zhang, B.; Hu, F.X.; Shen, B.G.

2017-01-01

Orthorhombic polycrystalline RCu 2 (R=Tb, Dy, Ho and Er) compounds were synthesized and the magnetic properties and magnetocaloric effect (MCE) were investigated in detail. All of the RCu 2 compounds are antiferromagnetic (AFM) ordered. As temperature increases, RCu 2 compounds undergo an AFM to AFM transition at T t and an AFM to paramagnetic (PM) transition at T N . Besides of the normal MCE around T N , large inverse MCE around T t was found in TbCu 2 compound. Under a field change of 0–7 T, the maximal value of inverse MCE is even larger than the value of normal MCE around T N for TbCu 2 compound. Considering of the normal and inverse MCE, TbCu 2 shows the largest refrigerant capacity among the RCu 2 (R=Tb, Dy, Ho and Er) compounds indicating its potential applications in low temperature multistage refrigeration. - Highlights: • Large inverse magnetocaloric effect is observed in TbCu 2 compound. • The AFM to AFM transition is observed in RCu 2 (R=Tb, Dy, Ho, Er) compounds. • The MCE performance of TbCu 2 compound is evaluated in a more comprehensively way.

Magnetic ordering of YPd{sub 2}Si-type HoNi{sub 2}Si and ErNi{sub 2}Si compounds

Energy Technology Data Exchange (ETDEWEB)

Morozkin, A.V., E-mail: morozkin@tech.chem.msu.ru [Department of Chemistry, Moscow State University, Leninskie Gory, House 1, Building 3, GSP-2, Moscow, 119992 (Russian Federation); Isnard, O. [CNRS, Insitut. Néel, 25 Rue Des Martyrs BP166 x, F-38042 Grenoble (France); Université Grenoble Alpes, Inst. Néel, F-38042 Grenoble (France); Nirmala, R. [Indian Institute of Technology Madras, Chennai 600 036 (India); Quezado, S.; Malik, S.K. [Departamento de Física Teórica e Experimental, Universidade Federal do Rio Grande do Norte, Natal 59082-970 (Brazil)

2016-12-01

Magnetic properties of YPd{sub 2}Si-type HoNi{sub 2}Si and ErNi{sub 2}Si were investigated via neutron diffraction and magnetisation measurements. HoNi{sub 2}Si and ErNi{sub 2}Si show ferromagnetic-like ordering at T{sub C} of 9 K and 7 K, respectively. The paramagnetic Weiss temperatures are 9 K and 11 K and the effective magnetic moments are 10.76 μ{sub B}/fu and 9.79 μ{sub B}/fu for HoNi{sub 2}Si and ErNi{sub 2}Si compounds, respectively. The HoNi{sub 2}Si and ErNi{sub 2}Si are soft ferromagnets with saturation magnetization of 8.1 μ{sub B}/fu and 7.5 μ{sub B}/fu, respectively at 2 K and in field of 140 kOe. The isothermal magnetic entropy change, ΔS{sub m}, has a maximum value of −15.6 J/kg·K at 10 K for HoNi{sub 2}Si and −13.9 J/kg·K at 6 K for ErNi{sub 2}Si for a field change of 50 kOe. Neutron diffraction study in zero applied field shows mixed ferromagnetic-antiferromagnetic ordering of HoNi{sub 2}Si at ~9 K and its magnetic structure is a sum of a-axis ferromagnetic F{sub a}, b-axis antiferromagnetic AF{sub b} and c-axis antiferrromagnetic AF{sub c} components of Pn′a2{sub 1}′={1, m_x′/[1/2, 1/2, 1/2], 2_y′/[0, 1/2, 0], m_z/[1/2, 0, 1/2]} magnetic space group and propagation vector K{sub 0}=[0, 0, 0]. The holmium magnetic moment reaches a value of 9.23(9) μ{sub B} at 1.5 K and the unit cell of HoNi{sub 2}Si undergoes isotropic contraction around the temperature of magnetic transition. - Graphical abstract: HoNi{sub 2}Si: mixed ferro-antiferromagnet (F{sub a}+AF{sub b}+AF{sub c}){sup K0} with Pn′a2{sub 1}′ magnetic space group and K{sub 0}=[0, 0, 0] propagation vector below 10 K. - Highlights: • Ferro-antiferromagnetic ordering is observed in HoNi{sub 2}Si at 9 K and in ErNi{sub 2}Si at 7 K. • HoNi{sub 2}Si is soft ferromagnet with ΔS{sub m} of −15.6 J/kg·K at 10 K in field of 0–50 kOe. • ErNi{sub 2}Si is soft ferromagnet with ΔS{sub m} of −13.9 J/kg·K at 6 K in field of 0–50 kOe. • HoNi{sub 2}Si shows mixed F�

Peculiarities of component interaction in {Gd, Er}-V-Sn Ternary systems at 870 K and crystal structure of RV6Sn6 stannides

International Nuclear Information System (INIS)

Romaka, L.; Stadnyk, Yu.; Romaka, V.V.; Demchenko, P.; Stadnyshyn, M.; Konyk, M.

2011-01-01

Highlights: → {Gd, Er}-V-Sn ternary systems at 870 K are characterized by formation of stannides with general compositions RV 6 Sn 6 . → Isostructural RV 6 Sn 6 compounds were also found with Y, Dy, Ho, Tm, and Lu. → The crystal structure of RV 6 Sn 6 compounds was determined by powder diffraction method. → Structural analysis showed that RV 6 Sn 6 compounds (R = Gd, Dy-Tm, Lu) are disordered; YV 6 Sn 6 is characterized by structure ordering. - Abstract: The phase equilibria in the Gd-V-Sn and Er-V-Sn ternary systems were studied at 870 K by means of X-ray and metallographic analyses in the whole concentration range. Both Gd-V-Sn and Er-V-Sn systems are characterized by formation of one ternary compound at investigated temperature, with stoichiometry RV 6 Sn 6 (SmMn 6 Sn 6 -type, space group P6/mmm, a = 0.55322(3) nm, c = 0.91949(7) nm for Gd, a = 0.55191(2) nm, c = 0.91869(8) nm for Er). Solubility of the third component in the binary compounds was not observed. Compounds with the SmMn 6 Sn 6 -type were also found with Dy, Ho, Tm, and Lu, while YV 6 Sn 6 compound crystallizes in HfFe 6 Ge 6 structure type. All investigated compounds are the first ternary stannides with rare earth elements and vanadium.

Vortex operation in Er:LuYAG crystal laser at ∼1.6 μm

Science.gov (United States)

Liu, Qiyao; Zhao, Yongguang; Zhou, Wei; Shen, Deyuan

2017-09-01

An Er3+-doped Lu1.5Y1.5Al5O12 (Er:LuYAG) solid-state laser with direct generation of optical vortex is reported. The vortex laser operation was realized through being pumped by an annular beam at 1532 nm, which was reformatted by a specially fabricated optical mirror. With two different laser output couplers of 10% and 20% transmissions, pure LG01 mode lasers with right-handedness at 1647.7 nm and 1619.5 nm were yielded from a simple two-mirror cavity, respectively, without any helicity control optical element. Furthermore, stable pulse trains at 1647.7 nm have been achieved via employing an acousto-optic Q-switch, and ∼0.66 mJ pulsed energy and ∼65 ns pulse duration were finally obtained at 1 kHz repetition rate, corresponding to a peak power of ∼10.2 kW. The generated pulse vortex maintained LG01 mode with well-determined right-handedness, as in the case of cw laser operation.

Efficient Ho:LuLiF4 laser diode-pumped at 1.15 μm.

Science.gov (United States)

Wang, Sheng-Li; Huang, Chong-Yuan; Zhao, Cheng-Chun; Li, Hong-Qiang; Tang, Yu-Long; Yang, Nan; Zhang, Shuai-Yi; Hang, Yin; Xu, Jian-Qiu

2013-07-15

We report the first laser operation based on Ho(3+)-doped LuLiF(4) single crystal, which is directly pumped with 1.15-μm laser diode (LD). Based on the numerical model, it is found that the "two-for-one" effect induced by the cross-relaxation plays an important role for the laser efficiency. The maximum continuous wave (CW) output power of 1.4 W is produced with a beam propagation factor of M(2) ~2 at the lasing wavelength of 2.066 μm. The slope efficiency of 29% with respect to absorbed power is obtained.

Thermal stability of LiNaR2F8 compounds (R=Ho-Lu, Y)

International Nuclear Information System (INIS)

Fedorov, P.P.; Medvedeva, L.V.; Bondareva, O.S.; Sobolev, B.P.

1990-01-01

Monoclinic pseudorhombic compound mentioned in the title are investigated. It is determined, that the compounds are stable within temperature narrow range: Ho - 575-693 degC, Er - 566-712deg C, Tm - 560-710 deg C, Yb - less than 685 deg C, Y - 580-712 deg C. Triangulation of LiF-NaF-YF 3 system is carried out

Neutron scattering studies of the RENi2B2C (RE = Lu, Y, Ho, Er): Lattice dynamics

International Nuclear Information System (INIS)

Bullock, M.

1998-01-01

The first chapter gives a brief overview of the system discussed in this dissertation. Chapters 2--5 and Appendix B of this dissertation consist of papers that are published, or have been submitted, which show experimental data regarding the phonon softening of LuNi 2 B 2 C. These papers have been removed and processed separately. Chapter 6 will contain a summary of the conclusions up to date. Appendix A will consist of a brief derivation of χ(q) which is talked about in the introduction of the dissertation. Appendix B will contain a Born-von Karman model fit to the experimental LuNi 2 B 2 C data and a comparison with experimental data. Appendix C will contain a brief summary of the work done on LuNi 2 B 2 C as well as a complete listing of experimental data taken on the crystals which may be needed later for theoretical models of this system. Appendix D will outline a brief introduction covering some of the field theory used in the theoretical work for this thesis

2.05 xB5m emission properties and energy transfer mechanism of germanate glass doped with Ho3+, Tm3+, and Er3+

Science.gov (United States)

Xu, Rongrong; Wang, Meng; Tian, Ying; Hu, Lili; Zhang, Junjie

2011-03-01

A new GeO2-Ga2O3-Na2O-BaO-La2O3 germanate glass doped with Ho2O3, Tm2O3, and Er2O3 has been investigated for application as a laser material at the 2 μm region. The spectroscopic properties and energy transfer mechanisms of Ho3+ sensitized by Tm3+ and Er3+ are analyzed. Based on the measurement of absorption spectra, the Judd-Ofelt intensity parameters, radiation emission probability, branching ratio, and lifetime of Ho3+ are calculated to evaluate the spectroscopic properties. The maximum value of emission cross section of Ho3+ around 2.05 μm is 8.003×10-21 cm2, which indicates that the germanate glass may provide high gain as a good medium in high-power level laser system. It is also found that the 2.05 μm emission of Ho3+:5I7→5I8 can be greatly enhanced by adding the proper amount of Er2O3 and Tm2O3 under excitation at 808 nm. With the large energy transfer coefficient, the high efficient energy transfer process among Ho3+, Tm3+, and Er3+ ions is proven.

Magnetocrystalline anisotropy and magnetic domain structure of ErFe11Ti and HoFe11Ti compounds

International Nuclear Information System (INIS)

Pastushenkov, Yury G.; Skokov, Konstantin P.; Skourski, Yury; Lebedeva, Ludmila; Ivanova, Tatyana; Grushichev, Anton; Mueller, Karl-Hartmut

2006-01-01

Tetragonal ThMn 12 -type single crystalline ErFe 11 Ti and HoFe 11 Ti samples have been investigated by magnetization measurements and by observations of the magnetic domain structure at various temperatures between 10 and 300K. The magnetic structure of ErFe 11 Ti changes from room temperature 'easy axis' (c-axis) type to conical at spin-reorientation temperature T SR =50K. The HoFe 11 Ti has a metastable anisotropy energy minimum in the a-direction at T<40K. It leads to a first-order magnetization process detected by magnetization measurements along the a-axis in this temperature region

EPR experiments in LiTbF4, LiHoF4, and LiErF4 at submillimeter frequencies

DEFF Research Database (Denmark)

Magariño, J.; Tuchendler, J.; Beauvillain, P.

1980-01-01

Electron-paramagnetic-resonance experiments in LiTbF4, LiHoF4, and LiErF4 have been performed at frequencies between 70 and 600 GHz, in magnetic fields up to 60 kG and in the temperature range 1.4......Electron-paramagnetic-resonance experiments in LiTbF4, LiHoF4, and LiErF4 have been performed at frequencies between 70 and 600 GHz, in magnetic fields up to 60 kG and in the temperature range 1.4...

Spectroscopic studies of the energy transfer processes important to obtain holmium laser action in the Er:Tm:Ho:YLF

International Nuclear Information System (INIS)

Tarelho, Luiz Vicente Gomes

1995-01-01

There are several processes of energy transfer between Er, Tm and Ho ions in YLF crystal that could be evaluated using the Foerster-Dexter method. Energy transfer processes, important to understand Holmium laser action, were studied, specially involving the energy transfer between the first excited states of Er and Tm donors and Ho acceptor. The back-transfer processes were evaluated too in order to minimize the system losses. Another important process to understand Ho laser action in the host is the energy diffusion mechanism between donor ions due to excitation migration processes which take place before the energy transfer to Ho. The proposed model of energy transfer was developed to include the diffusion mechanism between donors in the absence and presence of the acceptors. The energy transfer probability was evaluated including the back-transfer processes besides the diffusion assistance. A laser medium model based on the fundamental spectroscopic parameters was used in order to determine the ideal donor acceptor concentrations in order to maximize the laser action of Ho at 2,1 μm. (author)

Rare earth elements in the Pacific and Atlantic Oceans. [Pr, Tb, Ho, Tm, Lu, La, Nd, Sm, Eu, Gd, Yb, Ce

Energy Technology Data Exchange (ETDEWEB)

Baar, H J.W. de; Bacon, M P; Brewer, P G; Bruland, K W

1985-09-01

The first profiles of Pr, Tb, Ho, Tm and Lu in the Pacific Ocean, as well as profiles of La, Ce, Nd, Sm, Eu, Gd and Yb are reported. Concentrations of REE (except Ce) in the deep water are two to three times higher than those observed in the deep Atlantic Ocean. Surface water concentrations are typically lower than in the Atlantic Ocean, especially for the heavier elements Ho,Tm,Yb and Lu. Cerium is strongly depleted in the Pacific water column, but less so in the oxygen minimum zone. The distribution of the REE group is consistent with two simultaneous processes: (1) cycling similar to that of opal and calcium carbonate, and (2) adsorptive scavenging by settling particles and possibly by uptake at ocean boundaries. However, the first process can probably not be sustained by the low REE contents of shells, unless additional adsorption on surfaces is invoked. The second process, adsorptive scavenging, largely controls the oceanic distribution and typical seawater pattern of the rare earths. (author).

Synthesis of NaLuF4:Er3+, Yb3+, Ce3+ nanoparticles and study of photoluminescent properties in C - band

Directory of Open Access Journals (Sweden)

Khaydukov K.V.

2017-01-01

Full Text Available The novel core@shell nanocrystals β-NaLuF4@NaLuF4 co-doped with rare-earth ions Er3+, Yb3+, Ce3+ have been synthesized. The nano-particles indicate the intensive lines of anti-Stokes luminescence in the telecommunication С - band of spectrum when pumped at 970-980 nm. The nanoparticles have been characterized by transmission electron microscopy and spectrofluorimetry. The nanoparticles have a size 40-80 nm and possess the intensive photo-luminescence 73 nm bandwidth centered around 1530 nm. The photo-luminescence kinetics of β-NaLuF4: Er3+/ Yb3+/ Ce3+ has been studied in IR range of spectrum. We have demonstrated that doping with cerium ions prevents serial stepwise excitation of erbium ions. Consequently, the lifetime of transition in erbium 4I13/2→4I15/2 has risen up to 6.9 ms. Intensity of 1530 nm line in Er3+ ions excited at 980 nm has been increased up to 6 times. Therefore, the nanoparticles are applicable to fabrication of compact waveguide amplifiers for C - band.

Electric quadrupole moments and strong interaction effects in pionic atoms of 165Ho, 175Lu, 176Lu, 179Hf and 181Ta

International Nuclear Information System (INIS)

Olaniyi, B.; Shor, A.; Cheng, S.C.; Dugan, G.; Wu, C.S.

1981-05-01

The effective quadrupole moments Q sub(eff) of the nuclei of 165 Ho, 175 Lu, 176 Lu, 179 Hf and 181 Ta were accurately measured by detecting the pionic atom 5g-4f x-rays of the elements. The spectroscopic quadrupole moments, Q sub(spec), were obtained by correcting Q sub(eff) for nuclear finite size effect, distortion of the pion wave function by the pion-nucleus strong interaction, and contribution to the energy level splittings by the strong interaction. The intrinsic quadrupole moments, Q 0 , were obtained by projecting Q sub(spec) into the frame of reference fixed on the nucleus. The shift, epsilon 0 , and broadening, GAMMA 0 , of the 4f energy level due to the strong interactions between the pion and the nucleons for all the elements were also measured. Theoretical values of epsilon 0 and GAMMA 0 were calculated and compared to the experimental values. The measured values of Q 0 were compared with the existing results in muonic and pionic atoms. The measured values of epsilon 0 and GAMMA 0 were also compared with existing values. (auth)

Selective separation of yttrium by CA-100 in the presence of a complexing agent

International Nuclear Information System (INIS)

Sun Xiaobo; Wang Yige; Li Deqian

2006-01-01

The selective separation of Y from yttrium solution containing small heavy rare earth (HRE) impurities (Ho, Er, Tm, Yb, Lu) by liquid-liquid extraction using CA-100 in the presence of a water-soluble complexing agent of ethylenediaminetetraacetic acid (EDTA) was experimentally studied at 298 K. Experiments were carried out in two feeds, Feed-I: [RE] f = 4.94 x 10 -3 M, Y = 98.5%, HRE (Ho, Er, Tm, Yb, Lu) = 1.5%; Feed-II: [RE] f = 4.94 x 10 -3 M, Y = 99.9%, HRE (Ho, Er, Tm, Yb, Lu) = 0.1%, as a function of equilibrium pH (pH eq ), the concentration ratio of [EDTA]:[HRE impurities]. It was shown that the extraction of HRE in the presence of EDTA was suppressed when compared to that of Y because of the masking effect, while the selective extraction of Y was enhanced and the separation factors increased to maximum at appropriate condition for Feed-I: Y/Ho = 1.53, Y/Er 3.09, Y/Tm = 5.61, Y/Yb = 12.04, Y/Lu = 27.51 at pH 4.37 and [EDTA]:[HRE impurities] = 4:1, for Feed-II: Y/Ho = 1.32, Y/Er = 1.91, Y/Tm = 2.00, Y/Yb 3.05, Y/Lu = 3.33 at pH 4.42 and [EDTA]:[HRE impurities] = 8:1. The separation and purification of Y by this method was discussed

Measurement of 167Er(n,p)167Ho reaction at 13.5 and 14.8 MeV

International Nuclear Information System (INIS)

Luo, Junhua; Liu, Jun; Han, Jiuning; Jiang, Li; Liu, Rong; Ge, Suhong; Liu, Zhenlai

2013-01-01

We have measured the 167 Er(n,p) 167 Ho cross-sections at two different neutron energies 13.5 and 14.8 MeV. Measurements were performed at Pd-300 neutron generator of Chinese Academy of Engineering Physics (CAEP) with monoenergetic neutrons produced via the 3 H(d,n) 4 He reaction using a tritium–titanium (T–Ti) target. Induced gamma activities were measured by a high-resolution gamma-ray spectrometer with high-purity germanium (HPGe) detector. The data for 167 Er(n,p) 167 Ho reaction cross-sections are reported to be 2.2±0.6 and 2.8±1.4 mb at 13.5±0.2 and 14.8±0.2 MeV incident neutron energies, respectively. The cross sections were also estimated with the TALYS-1.4 nuclear model code and compared with experimental data found in the literature, and with the comprehensive evaluation data in ENDF/B-VII.1 and JEFF-3.1/A libraries. - Highlights: • D–T neutron source was used to measure cross sections using activation method. • 27 Al(n,α) 24 Na was used as the monitor for the measurement. • The cross sections for the 167 Er(n,p) 167 Ho reactions have been measured. • Contribution of the interfering reaction 170 Er(n,α) 167 Dy was subtracted. • The results were compared with previous data and with evaluation data

Phase composition of iron-rich R-Fe-Si (R=Dy, Ho, Er) alloys

International Nuclear Information System (INIS)

Ivanova, G.V.; Makarova, G.M.; Shcherbakova, E.V.; Belozerov, E.V.

2005-01-01

Phase composition is studied in iron-rich alloys of R-Fe-Si (R=Dy, Ho, Er). In the as-cast state R 2 (Fe, Si) 17 of type Th 2 Ni 17 and R(Fe, Si) 12 compounds are observed; in the alloys of rated composition of R(Fe 0.85 Si 0.15 ) 8.5 (R=Dy, Er) a compound R 2 (Fe, Si) 17 of Th 2 Zn 17 -type is revealed as well. The annealing at 1273 K results in formation of Dy 3 (Fe, Si) 29 and also the compounds with the presumed composition of Dy 4 (Fe, Si) 41 and Ho 4 (Fe, Si) 41 . As this takes place the alloys contain a transition structure as well that represents a set of small-sized areas with various type short-range order in mutual displacement of Fe-Fe(Si) dumpbell chains. The process of phase formation at 1273 K is faced with difficulties. Even the annealing for 1000 h does not result in the state of equilibrium [ru

Crystal growth, spectroscopic characterization and laser operation of Tm3+ and Ho3+ codoped LiLuF4 crystal

Science.gov (United States)

Zhao, C. C.; Hang, Y.; Zhang, L. H.; He, X. M.; Yin, J. G.; Gong, J.; Yu, T.; Chen, W. B.

2012-02-01

Laser crystal Tm3+ and Ho3+ codoped LiLuF4 with high optical quality was grown by Czochralski technique. Its absorption and fluorescence spectra were investigated. A continuous wave output power of 1.12 W at 2066 nm was obtained with a slope efficiency of 24% by use of diode pumping. In the Q-switched mode, a slope efficiency of 18.9% and a maximum average power of 0.65 W were obtained.

Tungsten ditelluride for a nanosecond Ho,Pr:LiLuF4 laser at 2.95 µm

Science.gov (United States)

Yan, Zhengyu; Li, Tao; Zhao, Jia; Zhao, Shengzhi; Yang, Kejian; Li, Guiqiu; Li, Dechun; Zhang, Shuaiyi; Li, Jian

2018-04-01

The linear and nonlinear absorption characteristics of a home-built multilayer tungsten ditelluride (WTe2) saturable absorber at ~3 µm were demonstrated for the first time. A passively Q-switched Ho,Pr:LiLuF4 laser was realized by inserting the WTe2-saturable absorber into a plane-concave laser cavity. A maximum average output power of 128 mW, with a pulse duration of 366 ns at a repetition rate of 92 kHz was obtained under an absorbed pump power of 3.67 W, corresponding to a pulse energy of 1.4 µJ.

Scintillation properties of Nd{sup 3+}, Tm{sup 3+}, and Er{sup 3+} doped LuF{sub 3} scintillators in the vacuum ultra violet region

Energy Technology Data Exchange (ETDEWEB)

Yanagida, Takayuki, E-mail: yanagida@imr.tohoku.ac.jp [New Industry Creation Hatchery Center (NICHe), Tohoku University, 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai 980-8579 (Japan); Kawaguchi, Noriaki [Tokuyama Corporation Ltd., Shibuya 3-chome, Shibuya-ku, Tokyo 150-8383 Japan (Japan); Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, 980-8577 (Japan); Fukuda, Kentaro [Tokuyama Corporation Ltd., Shibuya 3-chome, Shibuya-ku, Tokyo 150-8383 Japan (Japan); Kurosawa, Shunsuke; Fujimoto, Yutaka; Futami, Yoshisuke; Yokota, Yuui [Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, 980-8577 (Japan); Taniue, Kojiro [Department of Physics, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo, Kyoto, 606-8502 (Japan); Sekiya, Hiroyuki [Kamioka Observatory, Institute for Cosmic Ray Research, University of Tokyo, Hida, 506-1205 (Japan); Kubo, Hidetoshi [Department of Physics, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo, Kyoto, 606-8502 (Japan); Yoshikawa, Akira [New Industry Creation Hatchery Center (NICHe), Tohoku University, 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai 980-8579 (Japan); Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, 980-8577 (Japan); Tanimori, Toru [Department of Physics, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo, Kyoto, 606-8502 (Japan)

2011-12-11

In order to develop novel vacuum ultra violet (VUV) emitting scintillators, we grew Nd 0.5%, Tm 0.5%, and Er 0.5% doped LuF{sub 3} scintillators by the {mu}-pulling down method, because LuF{sub 3} has a very wide band gap and Nd{sup 3+}, Tm{sup 3+}, and Er{sup 3+} luminescence centers show fast and intense 5d-4f emission in VUV region. Transmittance and X-ray induced radioluminescence were studied in these three samples using our original spectrometer made by Bunkou-Keiki company. In the VUV region, transmittance of 20-60% was achieved for all the samples. The emission peaks appeared at approximately 180, 165, and 164 nm for Nd{sup 3+}, Tm{sup 3+}, and Er{sup 3+} doped LuF{sub 3}, respectively. Using PMT R8778 (Hamamatsu), we measured their light yields under {sup 241}Am {alpha}-ray excitation. Compared with Nd:LaF{sub 3} scintillator, which has 33 photoelectrons/5.5 MeV {alpha}, Nd:LuF{sub 3} and Tm:LuF{sub 3} showed 900{+-}90 and 170{+-}20 ph/5.5 MeV-{alpha}, respectively. Only for the Nd doped one, we can detect {sup 137}Cs 662 keV {gamma}-ray photoabsorption peak and the light yield of 1200{+-}120 ph/MeV was measured. We also investigated their decay time profiles by picosecond pulse X-ray equipped streak camera, and the main decay component of Nd:LuF{sub 3} turned out to be 7.63 ns.

Formation enthalpies of LaLn'O{sub 3} (Ln'=Ho, Er, Tm and Yb) interlanthanide perovskites

Energy Technology Data Exchange (ETDEWEB)

Qi, Jianqi [Peter A. Rock Thermochemistry Laboratory and NEAT ORU, University of California, Davis, CA 95616 (United States); College of Physical Science and Technology, Sichuan University, Chengdu 610064 (China); Key Laboratory of Radiation Physics and Technology of Ministry of Education, Sichuan University, Chengdu 610064 (China); Key Laboratory of High Energy Density Physics of Ministry of Education, Sichuan University, Chengdu 610064 (China); Guo, Xiaofeng [Peter A. Rock Thermochemistry Laboratory and NEAT ORU, University of California, Davis, CA 95616 (United States); Mielewczyk-Gryn, Aleksandra [Peter A. Rock Thermochemistry Laboratory and NEAT ORU, University of California, Davis, CA 95616 (United States); Faculty of Applied Physics and Mathematics, Department of Solid State Physics, Gdansk University of Technology, Narutowicza 11/12, 80-233 Gdansk (Poland); Navrotsky, Alexandra, E-mail: anavrotsky@ucdavis.edu [Peter A. Rock Thermochemistry Laboratory and NEAT ORU, University of California, Davis, CA 95616 (United States)

2015-07-15

High-temperature oxide melt solution calorimetry using 3Na{sub 2}O·MoO{sub 3} at 802 °C was performed for interlanthanide perovskites LaLn'O{sub 3} (Ln'=Ho, Er, Tm and Yb) and lanthanide oxides (La{sub 2}O{sub 3}, Ho{sub 2}O{sub 3}, Er{sub 2}O{sub 3}, Tm{sub 2}O{sub 3} and Yb{sub 2}O{sub 3}). The enthalpies of formation of these interlanthanide perovskites from binary lanthanide oxides at room temperature (25 °C) were determined to be −8.3±3.4 kJ/mol for LaHoO{sub 3}, −9.9±3.0 kJ/mol for LaErO{sub 3}, −10.8±2.7 kJ/mol for LaTmO{sub 3} and −12.3±2.9 kJ/mol for LaYbO{sub 3}. There is a roughly linear relationships between these enthalpy values and the tolerance factor for these and for other LaM{sup 3+}O{sub 3} (M=In, Sc, Ga, Al, Fe and Cr) perovskites, confirming that the distortion of the perovskites as results from ionic radius difference of A-site and B-site cations, is the main factor determining the stability of these compounds. - Graphical abstract: A linear relationship between the enthalpy of formation and the tolerance factor for interlanthanide LaLn'O{sub 3} (Ln'=Ho, Er, Tm, and Yb) and other LaM{sup 3+}O{sub 3} (M=In, Sc, Ga, Al, Fe and Cr) perovskites. - Highlights: • Interlanthanide perovskites were synthesized by solid state reactions. • Their enthalpies of formation were measured by oxide melt solution calorimetry. • ΔH{sub f,ox} shows a linear relationship with tolerance factor.

Peculiarities of component interaction in {l_brace}Gd, Er{r_brace}-V-Sn Ternary systems at 870 K and crystal structure of RV{sub 6}Sn{sub 6} stannides

Energy Technology Data Exchange (ETDEWEB)

Romaka, L., E-mail: romakal@franko.lviv.ua [Inorganic Chemistry Department, Ivan Franko Lviv National University, Kyryla and Mefodiya str. 6, 79005 Lviv (Ukraine); Stadnyk, Yu. [Inorganic Chemistry Department, Ivan Franko Lviv National University, Kyryla and Mefodiya str. 6, 79005 Lviv (Ukraine); Romaka, V.V. [Department of Materials Engineering and Applied Physics, Lviv Polytechnic National University, Ustyyanovycha Str. 5, 79013 Lviv (Ukraine); Demchenko, P.; Stadnyshyn, M.; Konyk, M. [Inorganic Chemistry Department, Ivan Franko Lviv National University, Kyryla and Mefodiya str. 6, 79005 Lviv (Ukraine)

2011-09-08

Highlights: > {l_brace}Gd, Er{r_brace}-V-Sn ternary systems at 870 K are characterized by formation of stannides with general compositions RV{sub 6}Sn{sub 6}. > Isostructural RV{sub 6}Sn{sub 6} compounds were also found with Y, Dy, Ho, Tm, and Lu. > The crystal structure of RV{sub 6}Sn{sub 6} compounds was determined by powder diffraction method. > Structural analysis showed that RV{sub 6}Sn{sub 6} compounds (R = Gd, Dy-Tm, Lu) are disordered; YV{sub 6}Sn{sub 6} is characterized by structure ordering. - Abstract: The phase equilibria in the Gd-V-Sn and Er-V-Sn ternary systems were studied at 870 K by means of X-ray and metallographic analyses in the whole concentration range. Both Gd-V-Sn and Er-V-Sn systems are characterized by formation of one ternary compound at investigated temperature, with stoichiometry RV{sub 6}Sn{sub 6} (SmMn{sub 6}Sn{sub 6}-type, space group P6/mmm, a = 0.55322(3) nm, c = 0.91949(7) nm for Gd, a = 0.55191(2) nm, c = 0.91869(8) nm for Er). Solubility of the third component in the binary compounds was not observed. Compounds with the SmMn{sub 6}Sn{sub 6}-type were also found with Dy, Ho, Tm, and Lu, while YV{sub 6}Sn{sub 6} compound crystallizes in HfFe{sub 6}Ge{sub 6} structure type. All investigated compounds are the first ternary stannides with rare earth elements and vanadium.

Síntesis hidrotermal de monocristales LnMn2O5 (Ln= Y, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho y Er

Directory of Open Access Journals (Sweden)

Señarís Rodríguez, M. A.

2008-08-01

Full Text Available Ten single crystals of the series LnMn2O5 (Ln= Y, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho and Er were synthesized by hydrothermal synthesis in a single step and without subsequent thermal treatments from aqueous solutions of metals salts at 240 ºC. The obtained single crystals have a size of various micrometers and their morphology changes throughout the serie: they are polygonal in the case of the compounds with Ln= Pr, Nd, Sm, Eu and Gd and needle-like in the case of the compounds with Ln= Y, Tb, Dy, Ho and Er. After the analysis of the obtained products employing different conditions of synthesis we attributed the different morphology to a greater growth rate along the c axis when the smaller ions (Y, Tb, Dy, Ho y Er are involved, due to their better adaptation to the compound’s crystal structure.Se han conseguido preparar monocristales de 10 óxidos mixtos de la serie LnMn2O5 (Ln= Y, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho y Er mediante síntesis hidrotermal optimizada, en un único paso y sin tratamientos térmicos posteriores partiendo de las correspondientes sales metálicas en disolución acuosa a 240 ºC. Los monocristales obtenidos son relativamente grandes, de varias micras y su morfología varía a lo largo de la serie: es poligonal en el caso de los compuestos de los lantánidos del inicio de la serie (Ln= Pr, Nd, Sm, Eu y Gd y acicular en el caso de los compuestos de Y y de los lantánidos del final de la serie (Ln= Tb, Dy, Ho y Er. Tras el análisis de los productos obtenidos empleando distintas condiciones de síntesis atribuimos la diferente morfología a una mayor velocidad de crecimiento cristalino a lo largo del eje c cuando intervienen los iones más pequeños (Y, Tb, Dy, Ho y Er debido a la mejor adaptación de éstos últimos a la estructura cristalina del compuesto.

Ion-irradiation-induced phase transformation in rare earth sesquioxides (Dy2O3,Er2O3,Lu2O3)

International Nuclear Information System (INIS)

Tang, M.; Lu, P.; Valdez, J.A.; Sickafus, K.E.

2006-01-01

Polycrystalline pellets of cubic C-type rare earth structure (Ia3) Dy 2 O 3 , Er 2 O 3 , and Lu 2 O 3 were irradiated at cryogenic temperature (120 K) with 300 keV Kr ++ ions to a maximum fluence of 1x10 20 Kr/m 2 . Irradiated specimens were examined using grazing incidence x-ray diffraction and transmission electron microscopy. Ion irradiation leads to different radiation effects in these three materials. First, Dy 2 O 3 begins to transform to a monoclinic B-type rare earth structure (C2/m) at a peak dose of ∼5 displacements per atom (dpa) (corresponding to a fluence of 2x10 19 Kr/m 2 ). This transformation is nearly complete at a peak dose of 25 dpa (a fluence of 1x10 20 Kr/m 2 ). Er 2 O 3 also transforms to the B-type structure, but the transformation starts at a higher irradiation dose of about 15-20 dpa [a fluence of about (6-8)x10 19 Kr/m 2 ]. Lu 2 O 3 was found to maintain the C-type structure even at the highest irradiation dose of 25 dpa (a fluence of 1x10 20 Kr/m 2 ). No C-to-B transformation was observed in Lu 2 O 3 . The irradiation dose dependence of the C-to-B phase transformation observed in Dy 2 O 3 , Er 2 O 3 , and Lu 2 O 3 is closely related to the temperature dependence of the C-to-B phase transformation found in phase diagrams for these three materials

Magnetocrystalline anisotropy and magnetic domain structure of ErFe{sub 11}Ti and HoFe{sub 11}Ti compounds

Energy Technology Data Exchange (ETDEWEB)

Pastushenkov, Yury G. [Physics Department of Tver State University, 17000 Tver (Russian Federation); Skokov, Konstantin P. [Physics Department of Tver State University, 17000 Tver (Russian Federation); Skourski, Yury [Leibniz-Institute for Solid State and Material Research, 01171 Dresden (Germany); Lebedeva, Ludmila [Physics Department of Tver State University, 17000 Tver (Russian Federation); Ivanova, Tatyana [Physics Department of Moscow Stae University, 119889 Moscow (Russian Federation); Grushichev, Anton [Physics Department of Tver State University, 17000 Tver (Russian Federation)]. E-mail: yupast@tversu.ru; Mueller, Karl-Hartmut [Leibniz-Institute for Solid State and Material Research, 01171 Dresden (Germany)

2006-05-15

Tetragonal ThMn{sub 12}-type single crystalline ErFe{sub 11}Ti and HoFe{sub 11}Ti samples have been investigated by magnetization measurements and by observations of the magnetic domain structure at various temperatures between 10 and 300K. The magnetic structure of ErFe{sub 11}Ti changes from room temperature 'easy axis' (c-axis) type to conical at spin-reorientation temperature T{sub SR}=50K. The HoFe{sub 11}Ti has a metastable anisotropy energy minimum in the a-direction at T<40K. It leads to a first-order magnetization process detected by magnetization measurements along the a-axis in this temperature region.

In-band pumping of expitaxially grown Er:(Gd,Lu)2O3 waveguides for active integrated optical devices

NARCIS (Netherlands)

Kahn, A.; Kühn, H.; Heinrich, S.; Gün, T.; Tellkamp, F.; Petermann, K.; Bradley, J.; Ay, F.; Worhoff, Kerstin; Pollnau, Markus; Kuzminykh, Y.; Luo, Y.; Hoffmann, P.; Huber, G.

Monocrystalline lattice matched Er(0.6%):(Gd, Lu)2O3 films with thicknesses up to 3 �?�m and nearly atomically flat surfaces have been deposited on Y2O3 substrates by Pulsed Laser Deposition (PLD). The epitaxial growth has been verified in-situ by Reflection High Energy Electron Diffraction (RHEED).

Energy transfer characteristics of silicate glass doped with Er{sup 3+}, Tm{sup 3+}, and Ho{sup 3+} for ∼2 μm emission

Energy Technology Data Exchange (ETDEWEB)

Li, Ming; Liu, Xueqiang [Key Laboratory of Materials for High Power Laser, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800 (China); Graduate School of Chinese Academy of Sciences, Beijing 100039 (China); Guo, Yanyan [College of Materials Science and Engineering, Changchun University of Science and Technology, Changchun 130022 (China); Hu, Lili [Key Laboratory of Materials for High Power Laser, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800 (China); Zhang, Junjie [College of Materials Science and Engineering, China Jiliang University, Hangzhou 310 018 (China)

2013-12-28

A Er{sup 3+}/Tm{sup 3+}/Ho{sup 3+} tri-doped silicate glass with good thermal stability is prepared by melt-quenching method. Efficient ∼2 μm emission is observed under 808 nm laser excitation. It is found that the 2.0 μm emission of Ho{sup 3+} can be enhanced under the excitation at 808 nm by incorporating Er{sup 3+} and Tm{sup 3+}. Based on the measurement of absorption spectra, the Judd–Ofelt intensity parameters, radiation emission probability, and branching ratio are calculated to evaluate the spectroscopic properties simultaneously. The maximum value of emission cross section of Ho{sup 3+} is 3.54 × 10{sup −21} cm{sup 2} at 2008 nm. Additionally, the phonon assistance and the micro-parameters in the energy transfer process are quantitatively analyzed by using Dexter model. The energy transfer coefficient from Tm{sup 3+} to Ho{sup 3+} can reach as high as 21.44 × 10{sup −40} cm{sup 6}/s, respectively. The emission property together with good thermal property indicates that Er{sup 3+}/Tm{sup 3+}/Ho{sup 3+} tri-doped silicate glass is a potential kind of laser glass for efficient 2 μm laser.

Crystal structure of RCoIn5 (R - Ce, Pr, Nd, Sm, Gd, Tb, Dy, Ho, Y) and R2CoIn8 (R - Ce, Pr, Nd, Sm, Gd, Dy, Ho, Er, Tm, Y) compounds

International Nuclear Information System (INIS)

Kalychak, Ya.M.; Zaremba, V.I.; Baranyak, V.M.; Bruskov, V.A.; Zavalij, P.Yu.

1989-01-01

Usng X-ray diffraction method of monocrystal, crystal structure of HoCoIn 5 compound belonging to the HoCoGa 5 structural type is determined. Using the method of powder belonging of CeCoIn 5 structure to the HoCoGa 5 structural type is confirmed. Isostructural compounds with Y, Pr, Nd, Sm, Gd, Tb, Dy are detected. Their lattice periods are determined. Using the method of powder belonging of Ce 2 CoIn 8 compound structure to Ho 2 CoGa 8 structural type is determined. Isostructural compounds with Y, Pr, Nd, Sm, Gd, Dy, Ho, Er, Tm are detected and their lattice periods are determined

Judd–Ofelt analysis and transition probabilities of Er{sup 3+} doped KY{sub 1−x−y}Gd{sub x}Lu{sub y}(WO{sub 4}){sub 2} crystals

Energy Technology Data Exchange (ETDEWEB)

Martínez de Mendívil, Jon, E-mail: jon.martinez@uam.es [Departamento de Física de Materiales, Universidad Autónoma de Madrid, 28049 Madrid (Spain); Lifante, Ginés [Departamento de Física de Materiales, Universidad Autónoma de Madrid, 28049 Madrid (Spain); Pujol, Maria Cinta; Aguiló, Magdalena; Díaz, Francesc [Física i Cristalografia de Materials i Nanomaterials (FiCMA-FiCNA), Universitat Rovira i Virgili, Tarragona (Spain); Cantelar, Eugenio [Departamento de Física de Materiales, Universidad Autónoma de Madrid, 28049 Madrid (Spain)

2015-09-15

In this work the transition probabilities, radiative lifetimes and branching ratios of Er{sup 3+} ions in KY{sub 1−x−y}Gd{sub x}Lu{sub y}(WO{sub 4}){sub 2} crystals have been determined. With this aim, Er{sup 3+} doped KY{sub 1−x−y}Gd{sub x}Lu{sub y}(WO{sub 4}){sub 2} crystals have been grown by means of the high temperature Top-Seeded Solution Growth. A spectroscopic analysis of Er{sup 3+} ions in this crystal has been performed following anisotropic Judd–Ofelt analysis to obtain basic spectroscopic properties. A quantum efficiency over 97% has been determined for the {sup 4}I{sub 13/2}→{sup 4}I{sub 15/2} transition, indicating that this material is adequate for the development of lasers and amplifiers working in the third telecommunication window. - Highlights: • Er{sub 0.01}:KY{sub 1−x−y}Gd{sub x}Lu{sub y}(WO{sub 4}){sub 2} crystals have been grown. • Anisotropic Judd Ofelt analysis has been carried out. • Optical transition probabilities and branching ratios have been calculated. • Radiative and non-radiative lifetimes have been obtained.

Phase equilibria and crystalline structure of compounds in the Lu-Al and Lu-Cu-Al systems

International Nuclear Information System (INIS)

Kuz'ma, Yu.B.; Stel'makhovich, B.M.; Galamushka, L.I.

1992-01-01

Phase equilibria and crystal structure of compounds in Lu-Al and Lu-Cu-Al systems were studied. Existence of Lu 2 Al compound having the structure of the PbCl 2 type is ascertained. Diagram of phase equilibria of Lu-Cu-Al system at 870 K is plotted. Compounds Lu 2 (Cu,Al) 17 (the Th 2 Zn 17 type structure), Lu(Cu,Al) 5 (CaCu 5 type structure), Lu 6 (Cu,Al) 23 (Th 6 Mn 23 type structure) and ∼ LuCuAl 2 have been prepared for the first time. Investigation of component interaction in Lu-Cu-Al system shows that the system is similar to previously studied systems Dy-Cu-Al and Er-Cu-Al. The main difference consists in the absence of LuCuAl 3 compound with rhombic structure of the CeNi 2+x Sb 2-x type in the system investigated

A single crystal study of RE{sub 14}Co{sub 3}In{sub 3} (RE = Y, Tb, Dy, Ho, Er)

Energy Technology Data Exchange (ETDEWEB)

Zaremba, V.I.; Kalychak, Y.M.; Dzevenko, M.V. [Inorganic Chemistry Dept., Ivan Franko National Univ. of Lviv (Ukraine); Rodewald, U.Ch.; Heying, B.; Poettgen, R. [Inst. fuer Anorganische und Analytische Chemie, Westfaelische Wilhelms-Univ. Muenster (Germany)

2006-01-01

The rare earth-cobalt-indides RE{sub 14}Co{sub 3}In{sub 3} (RE = Y, Tb, Dy, Ho, Er) were prepared in polycrystalline form from the elements by arc-melting. Small single crystals were grown through a special annealing sequence. The compounds were investigated on the basis of X-ray powder and single crystal data: Lu{sub 14}Co{sub 2}In{sub 3} (Gd{sub 14}Co{sub 3}In{sub 2.7}) type, P4{sub 2}/nmc, Z = 4, a = 959.0(1), c = 2319.1(5) pm, wR2 = 0.055, 2289 F{sup 2} values, 65 variables for Y{sub 13.90}Co{sub 2.99}In{sub 3.02}, a = 953.8(1), c = 2315.8(5) pm, wR2 = 0.108, 2357 F{sup 2} values, 65 variables for Tb{sub 13.92}Co{sub 3.01}In{sub 2.92}, a = 949.24(3), c = 2296.5(1) pm, wR2 = 0.129, 2518 F{sup 2} values, 65 variables for Dy{sub 13.90}Co{sub 2.97}In{sub 2.95}, a = 946.3(1), c = 2289.0(5) pm, wR2 = 0.099, 2297 F{sup 2} values, 64 variables for Ho{sub 14}Co{sub 2.80}In{sub 2.89}, and a = 941.0(1), c = 2274.2(5) pm, wR2 = 0.140, 2450 F{sup 2} values, 65 variables for Er{sub 13.83}Co{sub 2.88}In{sub 3.10}. All RE{sub 14}Co{sub 3}In{sub 3} indides show a small degree of In/Co mixing (between 7 and 16% Co) on the 4c In1 site and defects on the 8g Co1 positions (between 84 and 95% Co). Except for the holmium compound, the RE{sub 14}Co{sub 3}In{sub 3} intermetallics also reveal RE/In mixing on the 4c RE1 sites, leading to the refined compositions. The seven crystallographically independent RE sites have between 9 and 10 nearest RE neighbors. The RE{sub 14}Co{sub 3}In{sub 3} structures consist of a complex intergrowth of rare earth based polyhedra. Both cobalt sites have a distorted trigonal-prismatic rare earth coordination. An interesting feature is the In2-In2 dumb-bell with an In2-In2 distance of 300 pm (for Ho{sub 14}Co{sub 2.80}In{sub 2.89}). The crystal chemistry of the RE{sub 14}Co{sub 3}In{sub 3} indides is discussed. (orig.)

Elastic Properties of Ho0.5Er0.5 Single Crystal

DEFF Research Database (Denmark)

Spichkin, Yu.I.; Bohr, Jakob; Tishin, A.M.

1996-01-01

The results of an investigation of the Young's modulus E and the interval friction Q-1 of a Ho0.5Er0.5 single crystal in the basal plane in the temperature range 4.2-400 K are reported. The measurements were carried out by the method of flexural autovibrations of a thin sample with sound frequency...... (3 kHz). The Young's modulus at 4.2 K was measured to be 154 GPa. From the obtained data the magnetic part of the Young's modulus and the Debye temperature theta-D=375 K were calculated. The anomalies on the Young's modulus and the interval friction temperature dependencies corresponding to magnetic...

The high-temperature modification of LuAgSn and high-pressure high-temperature experiments on DyAgSn, HoAgSn, and YbAgSn

Energy Technology Data Exchange (ETDEWEB)

Heying, B.; Rodewald, U.C.; Hermes, W.; Schappacher, F.M.; Riecken, J.F.; Poettgen, R. [Muenster Univ. (Germany). Inst. fuer Anorganische und Analytische Chemie; Heymann, G.; Huppertz, H. [Muenchen Univ. (Germany). Dept. fuer Chemie und Biochemie; Sebastian, C.P. [Max-Planck-Institut fuer Chemische Physik Fester Stoffe, Dresden (Germany)

2008-02-15

The high-temperature modification of LuAgSn was obtained by arc-melting an equiatomic mixture of the elements followed by quenching the melt on a water-cooled copper crucible. HT-LuAgSn crystallizes with the NdPtSb-type structure, space group P6{sub 3}mc: a = 463.5(1), c = 723.2(1) pm, wR2 = 0.0270, 151 F{sup 2}, and 11 variables. The silver and tin atoms build up two-dimensional, puckered [Ag{sub 3}Sn{sub 3}] networks (276 pm Ag-Sn) that are charge-balanced and separated by the lutetium atoms. The Ag-Sn distances between the [Ag{sub 3}Sn{sub 3}] layers of 294 pm are much longer. Single crystals of isotypic DyAgSn (a = 468.3(1), c = 734.4(1) pm, wR2 = 0.0343, 411 F{sup 2}, and 11 variables) and HoAgSn (a = 467.2(1), c = 731.7(2) pm, wR2 = 0.0318, 330 F{sup 2}, and 11 variables) were obtained from arc-melted samples. Under high-pressure (up to 12.2 GPa) and high-temperature (up to 1470 K) conditions, no transitions to a ZrNiAl-related phase have been observed for DyAgSn, HoAgSn, and YbAgSn. HT-TmAgSn shows Curie-Weiss paramagnetism with {mu}{sub eff} = 7.53(1) {mu}{sub B}/Tm atom and {theta}P = -15.0(5) K. No magnetic ordering was evident down to 3 K. HT-LuAgSn is a Pauli paramagnet. Room-temperature {sup 119}Sn Moessbauer spectra of HT-TmAgSn and HT-LuAgSn show singlet resonances with isomer shifts of 1.78(1) and 1.72(1) mm/s, respectively. (orig.)

Magnetic properties of lithium rare-earth fluorides: Ferromagnetism in LiErF4 and LiHoF4 and crystal-field parameters at the rare-earth and Li sites

DEFF Research Database (Denmark)

Hansen, P. E.; Johansson, Torben; Nevald, Rolf

1975-01-01

Single crystals of LiErF4 and LiHoF4 have been grown and their magnetic properties measured from 1.3 K to 300 K. LiHoF4 turned out to be a nearly ideal Ising ferromagnet with TC=1.30±0.05 K and a saturation magnetization along the crystalline c axis of (6.98±0.02)μB. In LiErF4 no ordering...... was observed, but extrapolation indicates that below 0.5 K it will be ferromagnetic with the magnetic moments in the crytalline ab plane. From the susceptibilities the crystal-field parameters Bnm with (n, m)=(2, 0), (4, 0), (4, 4), (6, 0), (6, 4) have been extracted giving for Er3+ in LiErF4: 430., -985......., 1185., -5., 740.+i135. (cm-1) and for Ho3+ in LiHoF4: 470., -825., 1050., -10., 760.+i150 (cm-1). The exchange constants were found to be small compared to the dipole interactions. Furthermore the 7Li NMR spectra have been obtained in these materials as well as in LiTbF4 thereby determining the second...

Fiber-optic thermometer application of thermal radiation from rare-earth end-doped SiO2 fiber

International Nuclear Information System (INIS)

Katsumata, Toru; Morita, Kentaro; Komuro, Shuji; Aizawa, Hiroaki

2014-01-01

Visible light thermal radiation from SiO 2 glass doped with Y, La, Ce, Pr, Nd, Eu, Tb, Dy, Ho, Er, Tm, Yb, and Lu were studied for the fiber-optic thermometer application based on the temperature dependence of thermal radiation. Thermal radiations according to Planck's law of radiation are observed from the SiO 2 fibers doped with Y, La, Ce, Pr, Eu, Tb, and Lu at the temperature above 1100 K. Thermal radiations due to f-f transitions of rare-earth ions are observed from the SiO 2 fibers doped with Nd, Dy, Ho, Er, Tm, and Yb at the temperature above 900 K. Peak intensities of thermal radiations from rare-earth doped SiO 2 fibers increase sensitively with temperature. Thermal activation energies of thermal radiations by f-f transitions seen in Nd, Dy, Ho, Er, Tm, and Yb doped SiO 2 fibers are smaller than those from SiO 2 fibers doped with Y, La, Ce, Pr, Eu, Tb, and Lu. Thermal radiation due to highly efficient f-f transitions in Nd, Dy, Ho, Er, Tm, and Yb ions emits more easily than usual thermal radiation process. Thermal radiations from rare-earth doped SiO 2 are potentially applicable for the fiber-optic thermometry above 900 K

Návrh a implementace internetového obchodu

OpenAIRE

Maťák, Lubomír

2010-01-01

Obsahem této práce je analýza a návrh elektronického obchodu pro firmu, zabývající se velkoobchodním prodejem elektromateriálu a poskytování služeb v oblasti dodávek elektromateriálu na stavbu různých projektů, jak ze státního, tak ze soukromého sektoru. Nejedná se o klasický internetový obchod formou B2C. Koncept této práce je navržen jako B2B. Hlavní myšlenkou je online komunikace dodavatele a odběratele a možná kontrola, jak stavu zakázky, tak stavu skladu pro případné další objednávky. ...

Studies of the energy transfer processes from Er3+ and Ho3+ to Nd3+, Tb3+ or Eu3+ in LiYF4 crystal and ZBLAN glass for the laser media optimization operating near 3μm region

International Nuclear Information System (INIS)

Jagosich, Fabio Henrique

2006-01-01

The energy transfer processes (ET) from the 4 I 13/2 ; 4 I 11/2 levels of Er 3+ and 5 I 6 levels of Ho 3+ ions in LiYF 4 (YLF) crystal and ZBLAN glass to Nd 3+ , Tb 3+ or Eu 3+ deactivators ions were studied. The micro parameters of these energy transfer processes were determined using the overlap integral method, and showed that Eu 3+ ion is the best deactivator of the first excited state of the Ho 3+ in YLF, and Nd 3+ is the best deactivator of the Er 3+ in YLF and ZBLAN materials. The 1.5 and 2.7μm emissions of Er 3+ and 2.1 and 2.9μm fluorescence of Ho 3+ were measured using short laser pulses excitations from a tunable OPO pumped 2w-Nd:YAG laser system. We proposed a criterion for discriminating the energy transfer processes assisted by excitation migration (diffusion or hopping) among donors. It was observed that diffusion model describes the ET process from the second excited state of the donor (Er 3+ or Ho 3+ ) independently of the C D-D /C D-A ratio, while the hopping model can describe the ET process involving the first excited state of donor. We proposed a modification of the hopping model in order to describe the experimental results for systems having C D-D /C D-A ≥ 10. Using the ET parameters, we determined that the best systems for laser action at 3μm are the Ho:Eu:YLF, Ho:Nd:YLF and Er:Nd:YLF systems. On the other hand, we found that Er 3+ doped (1.5 mol%) ZBLAN glasses, single and co-doped with Nd 3+ , Tb 3+ or Eu 3+ , do not show potential for laser action at 2.8μm. The up-conversion processes were studied in Er:YLF systems as a function of the Er 3+ concentration, and the excited state absorption (ESA) and up conversion by energy transfer (ETU) processes were discriminated using a time resolved fluorescence decays. It was observed that 980 nm is the most convenient wavelength for pumping the Er:YLF system for quasi cw laser operation at 2.8μm. The pump-probe technique was used to investigate the lifetime effects in Er:YLF system showing

Synthesis of Multicolor Core/Shell NaLuF4:Yb3+/Ln3+@CaF2 Upconversion Nanocrystals

Directory of Open Access Journals (Sweden)

Hui Li

2017-02-01

Full Text Available The ability to synthesize high-quality hierarchical core/shell nanocrystals from an efficient host lattice is important to realize efficacious photon upconversion for applications ranging from bioimaging to solar cells. Here, we describe a strategy to fabricate multicolor core @ shell α-NaLuF4:Yb3+/Ln3+@CaF2 (Ln = Er, Ho, Tm upconversion nanocrystals (UCNCs based on the newly established host lattice of sodium lutetium fluoride (NaLuF4. We exploited the liquid-solid-solution method to synthesize the NaLuF4 core of pure cubic phase and the thermal decomposition approach to expitaxially grow the calcium fluoride (CaF2 shell onto the core UCNCs, yielding cubic core/shell nanocrystals with a size of 15.6 ± 1.2 nm (the core ~9 ± 0.9 nm, the shell ~3.3 ± 0.3 nm. We showed that those core/shell UCNCs could emit activator-defined multicolor emissions up to about 772 times more efficient than the core nanocrystals due to effective suppression of surface-related quenching effects. Our results provide a new paradigm on heterogeneous core/shell structure for enhanced multicolor upconversion photoluminescence from colloidal nanocrystals.

Emission properties of hydrothermal Yb3+, Er3+ and Yb3+, Tm3+-codoped Lu2O3 nanorods: upconversion, cathodoluminescence and assessment of waveguide behavior

International Nuclear Information System (INIS)

Barrera, Elixir William; Pujol, MarIa Cinta; DIaz, Francesc; Choi, Soo Bong; Rotermund, Fabian; Park, Kyung Ho; Jeong, Mun Seok; Cascales, Concepcion

2011-01-01

Yb 3+ and Ln 3+ (Ln 3+ = Er 3+ or Tm 3+ ) codoped Lu 2 O 3 nanorods with cubic Ia3-bar symmetry have been prepared by low temperature hydrothermal procedures, and their luminescence properties and waveguide behavior analyzed by means of scanning near-field optical microscopy (SNOM). Room temperature upconversion (UC) under excitation at 980 nm and cathodoluminescence (CL) spectra were studied as a function of the Yb + concentration in the prepared nanorods. UC spectra revealed the strong development of Er 3+4 F 9/2 → 4I 15/2 (red) and Tm 3+1 G 4 → 3 H 6 (blue) bands, which became the pre-eminent and even unique emissions for corresponding nanorods with the higher Yb 3+ concentration. Favored by the presence of large phonons in current nanorods, UC mechanisms that privilege the population of 4 F 9/2 and 1 G 4 emitting levels through phonon-assisted energy transfer and non-radiative relaxations account for these observed UC luminescence features. CL spectra show much more moderate development of the intensity ratio between the Er 3+4 F 9/2 → 4 I 15/2 (red) and 2 H 11/2 , 4 S 3/2 → 4 I 15/2 (green) emissions with the increase in the Yb 3+ content, while for Yb 3+ , Tm 3+ -codoped Lu 2 O 3 nanorods the dominant CL emission is Tm 3+1 D 2 → 3 F 4 (deep-blue). Uniform light emission along Yb 3+ , Er 3+ -codoped Lu 2 O 3 rods has been observed by using SNOM photoluminescence images; however, the rods seem to be too thin for propagation of light.

Anti-Fibrotic Effect of Losartan, an Angiotensin II Receptor Blocker, Is Mediated through Inhibition of ER Stress via Up-Regulation of SIRT1, Followed by Induction of HO-1 and Thioredoxin

Directory of Open Access Journals (Sweden)

Hyosang Kim

2017-01-01

Full Text Available Endoplasmic reticulum (ER stress is increasingly identified as modulator of fibrosis. Losartan, an angiotensin II receptor blocker, has been widely used as the first choice of treatment in chronic renal diseases. We postulated that anti-fibrotic effect of losartan is mediated through inhibition of ER stress via SIRT1 (silent mating type information regulation 2 homolog 1 hemeoxygenase-1 (HO-1/thioredoxin pathway. Renal tubular cells, tunicamycin (TM-induced ER stress, and unilateral ureteral obstruction (UUO mouse model were used. Expression of ER stress was assessed by Western blot analysis and immunohistochemical stain. ER stress was induced by chemical ER stress inducer, tunicamycin, and non-chemical inducers such as TGF-β, angiotensin II, high glucose, and albumin. Losartan suppressed the TM-induced ER stress, as shown by inhibition of TM-induced expression of GRP78 (glucose related protein 78 and p-eIF2α (phosphospecific-eukaryotic translation initiation factor-2α, through up-regulation of SIRT1 via HO-1 and thioredoxin. Losartan also suppressed the ER stress by non-chemical inducers. In both animal models, losartan reduced the tubular expression of GRP78, which were abolished by pretreatment with sirtinol (SIRT1 inhibitor. Sirtinol also blocked the inhibitory effect of losartan on the UUO-induced renal fibrosis. These findings provide new insights into renoprotective effects of losartan and suggest that SIRT1, HO-1, and thioredoxin may be potential pharmacological targets in kidney diseases under excessive ER stress condition.

[Luís Gomes Ferreira reports on the health of slaves in his work entitled Erário mineral (1735)].

Science.gov (United States)

Eugênio, Alisson

2015-01-01

The article analyzes the reports of Luís Gomes Ferreira published in his manual on practical medicine entitled Erário mineral, of 1735, on the most common illnesses in captivity. It is shown that such reports can be interpreted as a criticism of the social relations of the slave era by issuing some warnings to the landowners who failed to look after the health of their slaves.

Photoabsorption by the 3d shell in Ce, Pr, Ho, and Er: Observations and calculations

International Nuclear Information System (INIS)

Sugar, J.; Brewer, W.D.; Kalkowski, G.; Kaindl, G.; Paparazzo, E.

1985-01-01

Improved 3d photoabsorption spectra of the series of rare-earth fluorides have been obtained by recording total electron yield and using monochromatized synchrotron radiation. They are compared with predicted spectra resulting from an average-of-configuration calculation of wave functions employing radial integrals adjusted to the observed spectrum in each case; results are presented here for Ce, Pr, Ho, and Er spectra. Improved resolution of the Ce spectrum permitted for the first time a determination of the proper scaling for all of the electrostatic parameters

Neutron scattering study on R2PdSi3 (R=Ho,Er,Tm) compounds

International Nuclear Information System (INIS)

Tang, Fei

2010-01-01

Previous studies on the family of inter-metallic rare-earth compounds R 2 PdSi 3 revealed multifaceted magnetic properties, for instance, spin-glass like behavior. Experimental observations include: Signs of a crystallographic superstructure, complicated magnetic structures both in zero field and in applied magnetic fields as well as a generic phase in applied fields for compounds in the series with the heavy rare-earths R=Gd, Tb, Dy, Ho, Er and Tm. This thesis expands the studies on the magnetic properties of R 2 PdSi 3 employing mainly neutron scattering on single crystals with the focus on the compounds with R=Ho, Er and Tm. A detailed analysis of the crystallographic superstructure using modulation wave approach and group theory is presented. The resulting structure implies the existence of two different rare-earth sites with reduced symmetry and an arrangement of the different sites according to sequences as determined by the superstructure. It is shown that the reduced symmetry of the rare-earth sites is explicitly observed in the energy spectra of inelastic neutron scattering. The results on the magnetic structures and excitations are shown and discussed in the framework of the superstructure model. Specifically the generic phase in applied fields is interpreted as a direct consequence of the crystallographic superstructure. It is rather unusual that a crystallographic superstructure is playing such a decisive, and through the field dependence also tunable role in determining the magnetic properties as observed in R 2 PdSi 3 . The mediating interactions between the crystallographic part and the magnetic part of the system are discussed. (orig.)

Slow magnetic relaxation and single-molecule toroidal behaviour in a family of heptanuclear {Cr"I"I"ILn"I"I"I_6} (Ln=Tb, Ho, Er) complexes

Energy Technology Data Exchange (ETDEWEB)

Vignesh, Kuduva R. [IITB-Monash Research Academy, IIT Bombay, Powai, Mumbai (India); Langley, Stuart K. [School of Science and the Environment, Division of Chemistry, Manchester Metropolitan University, Manchester (United Kingdom); Swain, Abinash; Rajaraman, Gopalan [Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai (India); Moubaraki, Boujemaa; Murray, Keith S. [School of Chemistry, Monash University, Clayton, VIC (Australia); Damjanovic, Marko; Wernsdorfer, Wolfgang [Institute Neel, CNRS, Universite Grenoble Alpes, Grenoble (France); Institute of Nanotechnology (INT), Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen (Germany)

2018-01-15

The synthesis, magnetic properties, and theoretical studies of three heterometallic {Cr"I"I"ILn"I"I"I_6} (Ln=Tb, Ho, Er) complexes, each containing a metal topology consisting of two Ln{sub 3} triangles connected via a Cr{sup III} linker, are reported. The {CrTb_6} and {CrEr_6} analogues display slow relaxation of magnetization in a 3000 Oe static magnetic field. Single-crystal measurements reveal opening up of the hysteresis loop for {CrTb_6} and {CrHo_6} molecules at low temperatures. Ab initio calculations predict toroidal magnetic moments in the two Ln{sub 3} triangles, which are found to couple, stabilizing a con-rotating ferrotoroidal ground state in Tb and Ho examples and extend the possibility of observing toroidal behaviour in non Dy{sup III} complexes for the first time. (copyright 2018 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim)

MoTe2 saturable absorber for passively Q-switched Ho,Pr:LiLuF4 laser at ∼3 μm

Science.gov (United States)

Yan, Zhengyu; Li, Tao; Zhao, Shengzhi; Yang, Kejian; Li, Dechun; Li, Guiqiu; Zhang, Shuaiyi; Gao, Zijing

2018-03-01

Multilayer molybdenum ditelluride (MoTe2) nanosheets were prepared by liquid-phase exfoliation (LPE) method. A YAG-based MoTe2 saturable absorption (SA) was consequently fabricated. The MoTe2-SA was employed in a passively Q-switched Ho,Pr:LiLuF4 laser at 2.95 μm. Under the absorbed pump power of 3.8 W, an average output power of 90 mW was achieved. The shortest pulse duration of 670 ns was generated with an output power of 73 mW and a repetition rate of 76.46 kHz, corresponding to a pulse energy of 0.95 μJ.

Transport properties of Y1-xRxCo2 (R=Er, Ho) in magnetic field

International Nuclear Information System (INIS)

Uchima, Kiyoharu; Nakama, Takao; Takaesu, Yoshinao; Misashi, Masataka; Yagasaki, Katsuma; Hedo, Masato; Uwatoko, Yoshiya; Burkov, Alexander T.

2006-01-01

Thermopower S and resistivity ρ of Y 1-x R x Co 2 (R=Er, Ho) compounds have been measured in the temperature range from 1.5 to 300-bar K under magnetic fields up to 15-bar T. Strong enhancement of resistivity and fundamental changes in temperature variation of thermopower are observed at low temperatures in the compounds within the composition range where uniform Co 3d magnetization collapses. The magnetic state of Co 3d electrons has a dominant effect on the characteristic behavior of S and ρ in these compounds

Investigation of A = 152 radioactivities with mass-separated sources: Identification of /sup 152/Lu

International Nuclear Information System (INIS)

Toth, K.S.; Sousa, D.C.; Nitschke, J.M.; Wilmarth, P.A.

1987-01-01

Nuclides with A = 152 were produced in /sup 58/Ni bombardments of /sup 96/Ru and their decay properties were investigated following on-line mass separation. The isotope /sup 152/Lu (T/sub 1/2/ = 0.7 +- 0.1 s) was identified by γ rays in its β-decay daughter, /sup 152/Yb. Based on its decay characteristics, the parent state has a probable spin and parity assignment of (4,5,6 - ). Several new transitions were observed to follow the β decays of /sup 152/Yb and the /sup 152/Tm low-spin isomer; they established previously unknown levels in both /sup 152/Tm and /sup 152/Er. The additional γ rays in /sup 152/Yb decay reduce from 100% to 88% the direct feeding to the one excited state in /sup 152/Tm that had been known earlier. Nevertheless, the corresponding logft value is calculated to be 3.5, indicating that this is an allowed β transition which connects the 0 + parent with a 1 + excited state in /sup 152/Tm. By comparing the β-decay rates of /sup 148/Dy and /sup 152/Ho, and the α- and β-decay rates of /sup 152/Er, an α branch of 90 +- 4 % was deduced for /sup 152/Er

Synthesis and structural characterization of inorganic luminescent materials of Cs2NaErBr6 and Cs2NaHoBr6

International Nuclear Information System (INIS)

Poblete, V.H; Fack, G

2003-01-01

The synthesis and structural characterization is described of two luminescent materials, with technological [1] and spectroscopic [2] interest, whose crystallographic charts have not been published in the literature. The synthesis of both systems: Cs 2 NaErBr 6 and CS 2 NaHoBr 6 , was done using solid state reactions in a controlled environment. The thermal analyses DTA/TGA, applied with a temperature gradient of 10 o C/min., established crystallization ranges of 490,4 o C to 545,4 o C, for the elpasolite CS 2 NaHoBr 6 and 501 o C to 556 o C, for the structure CS 2 NaErBr 6 .. The heat vacuum treatments were carried out at 505 o C and 526 o C respectively, obtaining optimum crystallization. The structural characterization was performed with powdered X-ray diffraction (XRD). The range between 12 o and 80 o (2θ), was analyzed for 3352 points, measured steps of 0.02 o (2θ using the Rietveld profile refining program. The following crystallographic parameters were established: a 0 = 11,279(1), and 11,293(4) Angstroms, for the two structures analyzed, respectively. The relationship R exp wp in both cases is highly accurate for the 32 test lines that were analyzed. The structures present cubic closed packing Cs 1+ 3 Cl 1- , with Ho 3+ and Er 3+ atoms, filling the octahedral holes. The test data obtained will be very useful for completing the mass of experimental data needed to develop the design engineering, with specific applications for luminescent devices (au)

Measurement of the K X-ray absorption jump factors and jump ratios of Gd, Dy, Ho and Er by attenuation of a Compton peak

International Nuclear Information System (INIS)

Budak, G.; Polat, R.

2004-01-01

The X-ray absorption jump factor and jump ratio of Gd, Dy, Ho and Er were measured with a Si(Li) detector by attenuation, with Gd, Dy, Ho and Er foil, a Compton peak produced by the scattering of the 59.5 keV Am-241 Gamma rays. Al was chosen as secondary exciter. The experimental absorption jump factors and jump ratios are compared with the theoretical estimates of WinXcom (Radiat. Phys. Chem. 60 (2001) 23), McMaster (Compilation of X-ray cross sections UCRL-50174, 1969; Sec. II. Rev. I), Broll (X-ray Spectrom 15 (1986) 271), Hubbel and Seltzer (NISTIR (1995) 5632) and Budak (Radiat. Meas. accepted for publication). The present results constitute the first measurement for this combination of energy and elements, and good agreement is obtained between experiment and theory

Heat capacity jumps induced by magnetic field in the Er{sub 2}HoAl{sub 5}O{sub 12} garnet

Energy Technology Data Exchange (ETDEWEB)

Shevchenko, E.V. [Centre for Diagnostics of Functional Materials for Medicine, Pharmacology and Nanoelectronics, St. Petersburg State University, St. Petersburg, 198504 (Russian Federation); Charnaya, E.V., E-mail: charnaya@live.com [Physics Department, St. Petersburg State University, St. Petersburg, 198504 (Russian Federation); Lee, M.K. [Department of Physics, National Cheng Kung University, Tainan, 70101 Taiwan (China); NSC Instrument Center at NCKU, Tainan, 70101 Taiwan (China); Chang, L.J. [Department of Physics, National Cheng Kung University, Tainan, 70101 Taiwan (China); Khazanov, E.N.; Taranov, A.V. [Kotel' nikov Institute of Radio Engineering and Electronics RAS, 125009 (Russian Federation); Bugaev, A.S. [Moscow Institute of Physics and Technology, Moscow, 141700 (Russian Federation)

2017-01-30

Measurements of the heat capacity were carried out for the mixed Er{sub 2}HoAl{sub 5}O{sub 12} garnet at magnetic fields up to 15 T. The heat capacity variations at low temperatures were dominated by the Schottky anomalies. In addition, anomalous sharp steps in the heat capacity were observed in magnetic fields stronger than 8 T upon cooling as well as upon warming. The temperatures of the steps increased with increasing magnetic field. Jumps found upon cooling and warming were shifted relative to each other showing the thermal hysteresis. The sharp decrease in the heat capacity at low temperatures suggested the blocking of magnetic flips induced by strong enough magnetic fields. - Highlights: • Anomalous steps of the heat capacity were observed in the Er{sub 2}HoAl{sub 5}O{sub 12} garnet. • The steps are induced by magnetic field at low temperatures. • The temperatures of the steps increased with increasing magnetic field. • The steps show a pronounced thermal hysteresis. • The findings suggest the blocking of the magnetic moment flips at field.

Purification of a 166mHo solution by successive high-performance liquid chromatography and gravitational chromatography for half-life determination

International Nuclear Information System (INIS)

Florence Gueguen; Helene Isnard; Carole Bresson; Celine Caussignac; Guillaume Stadelmann; Anthony Nonell; Sebastien Mialle; Karsten Kossert; Frederic Chartier

2014-01-01

A methodology to purify a 166m Ho solution has been developed by a combination of activity and mass concentration measurements in order to further determine the 166m Ho half-life. The isobaric interference at m/q ≃ 166 requires Ho purification from non-natural Er with a high purification degree due to the large amount of Ho as opposed to Er. The Ho/Er separation was achieved using high-performance liquid chromatography on a semi-preparative column followed by purification on gravitational chromatography. The efficiency of the separation was evaluated after precise determination of the Er isotopic composition. The purification methodology enabled to separate Ho from Er. (author)

Solubility of La, Pr, Eu, Er and Lu in a media of 1M ionic force of NaCl by 303 K; Solubilidad de La, Pr, Eu, Er y Lu en medio de fuerza ionica 1M de NaCl, a 303 K

Energy Technology Data Exchange (ETDEWEB)

Ramirez G, J.J.; Solache R, M.J.; Jimenez R, M.; Rojas H, A. [Instituto Nacional de Investigaciones Nucleares, A.P. 18-1027, 11801 Mexico D.F. (Mexico)

2002-07-01

The solubility and the solubility product of La, Pr, Eu, Er and Lu in media of 1M ionic force of NaCl by 303 K was determined, by means of a radiochemical method and the pLn{sup -}pCH diagrams in free conditions of CO{sub 2} were constructed. Moreover, the non saturation and the saturated zones and with them the pCH precipitation bound were determined. Finally a comparison among the obtained data in this work and those reported in the literature in several media was realized. (Author)

Magnetic ordering in the rare earth iron germanates HoFeGe2O7 and ErFeGe2O7

DEFF Research Database (Denmark)

Cascales, C.; Puebla, E.G.; Klimin, S.

1999-01-01

RFeGe2O7 (R = Ho, Er) have been prepared in polycrystalline form, and their crystal structures have been refined from room-temperature high-resolution neutron diffraction data by the Rietveld method. Both materials are isostructural, space group P2(1)/m (no. 11), Z = 4. The most interesting feature...

Energy transfer between doubly doped Er3+, Tm3+and Ho3+ rare earth ions in SiO2 nanoparticles

CSIR Research Space (South Africa)

Dhlamini, MS

2011-04-01

Full Text Available + and Ho3+ ions are reported. Another emission peak in the near infra-red (NIR) region at 875 nm from Er3+ was also measured. Blue emission at 460 nm, red at 705 nm and a NIR peak in the region of 865 nmfrom Tm3+ were observed. Red, green and blue (RGB...

Structural and magnetic properties of two branches of the tripod-kagome-lattice family A2R3Sb3O14 (A = Mg, Zn; R = Pr, Nd, Gd, Tb, Dy, Ho, Er, Yb)

Science.gov (United States)

Dun, Z. L.; Trinh, J.; Lee, M.; Choi, E. S.; Li, K.; Hu, Y. F.; Wang, Y. X.; Blanc, N.; Ramirez, A. P.; Zhou, H. D.

2017-03-01

We present a systematic study of the structural and magnetic properties of two branches of the rare-earth tripod-kagome-lattice (TKL) family A2R3Sb3O14 (A = Mg, Zn; R = Pr, Nd, Gd, Tb, Dy, Ho, Er, Yb; here, we use abbreviation A-R, as in MgPr for Mg2Pr3Sb3O14 ), which complements our previously reported work on MgDy, MgGd, and MgEr [Z. L. Dun et al., Phys. Rev. Lett. 116, 157201 (2016), 10.1103/PhysRevLett.116.157201]. The present susceptibility (χdc, χac) and specific-heat measurements reveal various magnetic ground states, including the nonmagnetic singlet state for MgPr, ZnPr; long-range orderings (LROs) for MgGd, ZnGd, MgNd, ZnNd, and MgYb; a long-range magnetic charge ordered state for MgDy, ZnDy, and potentially for MgHo; possible spin-glass states for ZnEr, ZnHo; the absence of spin ordering down to 80 mK for MgEr, MgTb, ZnTb, and ZnYb compounds. The ground states observed here bear both similarities as well as striking differences from the states found in the parent pyrochlore systems. In particular, while the TKLs display a greater tendency towards LRO, the lack of LRO in MgHo, MgTb, and ZnTb can be viewed from the standpoint of a balance among spin-spin interactions, anisotropies, and non-Kramers nature of single-ion state. While substituting Zn for Mg changes the chemical pressure, and subtly modifies the interaction energies for compounds with larger R ions, this substitution introduces structural disorder and modifies the ground states for compounds with smaller R ions (Ho, Er, Yb).

Entropy change at the magnetostructural transition in RCo2(R=Dy,Ho,Er)

International Nuclear Information System (INIS)

Herrero-Albillos, J.; Bartolome, F.; Garcia, L.M.; Casanova, F.; Labarta, A.; Batlle, X.

2006-01-01

Differential scanning calorimetry under applied magnetic field has been used to characterize the magnetocaloric effect in ErCo 2 , HoCo 2 , and DyCo 2 . The entropy change ΔS at the first-order magnetostructural transition present in these materials has been studied by inducing the transition; sweeping the temperature at a constant field and sweeping the field at a constant temperature. The corresponding values of ΔS differ significantly due to the broadness of the transition, i.e. the initial and final states involved when the transition is field or temperature induced are different. In the field-induced case, the additional work done by the magnetic field extending through the region in which the transition spread accounts roughly for the observed difference

Studies of the energy transfer processes from Er{sup 3+} and Ho{sup 3+} to Nd{sup 3+}, Tb{sup 3+} or Eu{sup 3+} in LiYF{sub 4} crystal and ZBLAN glass for the laser media optimization operating near 3{mu}m region; Estudos dos processos de transferencia de energia dos ions de Er{sup 3+} e Ho{sup 3+} para os ions de Nd{sup 3+}, Tb{sup 3+} e Eu{sup 3+} no cristal de LiYF{sub 4} e no vidro ZBLAN para a otimizacao de meios laser ativos que operam na regiao de 3{mu}m

Energy Technology Data Exchange (ETDEWEB)

Jagosich, Fabio Henrique

2006-07-01

The energy transfer processes (ET) from the {sup 4}I{sub 13/2}; {sup 4}I{sub 11/2} levels of Er{sup 3+} and {sup 5}I{sub 6} levels of Ho{sup 3+} ions in LiYF{sub 4} (YLF) crystal and ZBLAN glass to Nd{sup 3+}, Tb{sup 3+} or Eu{sup 3+} deactivators ions were studied. The micro parameters of these energy transfer processes were determined using the overlap integral method, and showed that Eu{sup 3+} ion is the best deactivator of the first excited state of the Ho{sup 3+} in YLF, and Nd{sup 3+} is the best deactivator of the Er{sup 3+} in YLF and ZBLAN materials. The 1.5 and 2.7{mu}m emissions of Er{sup 3+} and 2.1 and 2.9{mu}m fluorescence of Ho{sup 3+} were measured using short laser pulses excitations from a tunable OPO pumped 2w-Nd:YAG laser system. We proposed a criterion for discriminating the energy transfer processes assisted by excitation migration (diffusion or hopping) among donors. It was observed that diffusion model describes the ET process from the second excited state of the donor (Er{sup 3+} or Ho{sup 3+}) independently of the C{sub D-D}/C{sub D-A} ratio, while the hopping model can describe the ET process involving the first excited state of donor. We proposed a modification of the hopping model in order to describe the experimental results for systems having C{sub D-D}/C{sub D-A} {>=} 10. Using the ET parameters, we determined that the best systems for laser action at 3{mu}m are the Ho:Eu:YLF, Ho:Nd:YLF and Er:Nd:YLF systems. On the other hand, we found that Er{sup 3+} doped (1.5 mol%) ZBLAN glasses, single and co-doped with Nd{sup 3+}, Tb{sup 3+} or Eu{sup 3+}, do not show potential for laser action at 2.8{mu}m. The up-conversion processes were studied in Er:YLF systems as a function of the Er{sup 3+} concentration, and the excited state absorption (ESA) and up conversion by energy transfer (ETU) processes were discriminated using a time resolved fluorescence decays. It was observed that 980 nm is the most convenient wavelength for pumping the Er

Synthesis and structural characterization of luminescent inorganic materials of the type CS2NaErBr6 and CS2NaHoBr6

International Nuclear Information System (INIS)

Poblete, V.H.; Fack, G.

2001-01-01

The synthesis and structural characterization is described of two luminescent materials, with technological [1] and spectroscopic [2] interest, whose crystallographic charts have not been published in the literature. The synthesis of both systems: Cs 2 NaErBr 6 and CS 2 NaHoBr 6 , was done using solid state reactions in a controlled environment. The thermal analyses DTA/TGA, applied with a temperature gradient of 10 o C/min., established crystallization ranges of 490,4 o C to 545,4 o C, for the elpasolite CS 2 NaHoBr 6 and 501 o C to 556 o C, for the structure CS 2 NaErBr 6 .. The heat vacuum treatments were carried out at 505 o C and 526 o C respectively, obtaining optimum crystallization. The structural characterization was performed with powdered X-ray diffraction (XRD). The range between 12 o and 80 o (2θ), was analyzed for 3352 points, measured steps of 0.02 o (2θ using the Rietveld profile refining program. The following crystallographic parameters were established: a 0 = 11,279(1), and 11,293(4) Angstroms, for the two structures analyzed, respectively. The relationship R exp wp in both cases is highly accurate for the 32 test lines that were analyzed. The structures present cubic closed packing Cs 1+ 3 Cl 1- , with Ho 3+ and Er 3+ atoms, filling the octahedral holes. The test data obtained will be very useful for completing the mass of experimental data needed to develop the design engineering, with specific applications for luminescent devices

Magnetic properties and low-temperature large magnetocaloric effect in the antiferromagnetic HoCu{sub 0.33}Ge{sub 2} and ErCu{sub 0.25}Ge{sub 2} compounds

Energy Technology Data Exchange (ETDEWEB)

Gao, R.L. [School of Metallurgy and Materials Engineering, Chongqing University of Science and Technology, Chongqing 401331 (China); Xu, Z.Y., E-mail: zhyxu@nim.ac.cn [National Institute of Metrology, Beijing 100029 (China); Wang, L.C. [State Key Laboratory for Magnetism, Institute of Physics, Chinese Academy of Sciences, Beijing 100190 (China); Dong, Q.Y.; Zhang, Y. [Department of Physics, Capital Normal University, Beijing 100048 (China); Liu, F.H. [National Space Science Center, Beijing 100190 (China); Mo, Z.J. [School of material Science and Engineering, Hebei University of Technology, Tianjin 300401 (China); Niu, E. [State Key Laboratory for Magnetism, Institute of Physics, Chinese Academy of Sciences, Beijing 100190 (China); Fu, C.L.; Cai, W.; Chen, G.; Deng, X.L. [School of Metallurgy and Materials Engineering, Chongqing University of Science and Technology, Chongqing 401331 (China)

2015-05-15

Highlights: • Antiferromagnetic material RCu{sub x}Ge{sub 2} of high purity was prepared. • Large MCE as −10.2 J/kg K and −10.5 J/kg K for RCu{sub x}Ge{sub 2} (Ho, Er) was obtained for field change of 0–50 kOe. • The RCu{sub x}Ge{sub 2} compounds with variable x had different transition temperature which made them suitable for ‘table-like’ magnetocaloric refrigerant. - Abstract: Magnetic properties and magnetocaloric effect (MCE) of HoCu{sub 0.33}Ge{sub 2} and ErCu{sub 0.25}Ge{sub 2} compounds have been investigated. The compounds were determined to be antiferromagnetic with the Néel temperatures T{sub N} = 9 K and 3.9 K, respectively. The critical transition magnetic fields for the metamagnetic transition from antiferromagnetic to ferromagnetic state below T{sub N} were determined to be 10 kOe for HoCu{sub 0.33}Ge{sub 2} at 5 K and 6 kOe for ErCu{sub 0.25}Ge{sub 2} at 2 K. Large MCE with the maximal values of magnetic entropy changes (ΔS{sub M}) as −10.2 J/kg K at 10.5 K were found in HoCu{sub 0.33}Ge{sub 2} for field changes of 0–70 kOe and −10.5 J/kg K at 5.5 K in ErCu{sub 0.25}Ge{sub 2} for field changes of 0–50 kOe, respectively. The large ΔS{sub M} around T{sub N} as well as no hysteresis loss made RCu{sub x}Ge{sub 2} competitive candidates as low temperature magnetic refrigerant.

Competing exchange interactions and their relevance for the magnetisation process in RMn6-xCrxSn6 powders (R=Y, Gd, Tb, Dy, Ho, Er)

International Nuclear Information System (INIS)

Brabers, J.H.V.J.; Zhou, G.F.; Colpa, J.H.P.; Buschow, K.H.J.; De Boer, F.R.

1994-01-01

The free-powder magnetisation of RMn 6-x Cr x Sn 6 compounds has been measured for compounds with R=Y, Gd, Tb, Dy, Ho, Er in fields up to 38 T, and interpreted in terms of a simple model, which is also outlined in this paper. From the measurements, estimates for the R-3d mean-field coupling constant (n RT ) could be derived for the cases where R=Gd, Tb, Dy, Ho, Er. In turn, the n RT values can be related to the microscopic spin-coupling constant (J RT ). In the case of YMn 6 Sn 6 the high-field measurement presents evidence for a very weak antiferromagnetic coupling between the Mn layers. Furthermore, values for the Mn moments (μ Mn ) were also derived from the magnetisation measurements. The estimated μ Mn values are of the order of 2.0 μ B . ((orig.))

Structural and sensing characteristics of Gd2Ti2O7, Er2TiO5 and Lu2Ti2O7 sensing membrane electrolyte–insulator–semiconductor for bio-sensing applications

International Nuclear Information System (INIS)

Pan, Tung-Ming; Liao, Pei-You; Chang, Kung-Yuan; Chi, Lifeng

2013-01-01

Highlights: ► The structural and sensing properties of Gd 2 Ti 2 O 7 , Er 2 TiO 5 and Lu 2 Ti 2 O 7 sensing films grown on Si substrates by reactive co-sputtering. ► The EIS device incorporating a Lu 2 Ti 2 O 7 sensing film exhibited a higher sensitivity, a larger drift rate, a higher hysteresis voltage, and a larger hysteresis gap than other sensing films. ► The impedance effect of EIS sensors has been investigated using C–V method. -- Abstract: This paper describes the structural and sensing characteristics of Gd 2 Ti 2 O 7 , Er 2 TiO 5 , and Lu 2 Ti 2 O 7 sensing membranes deposited on Si substrates through reactive co-sputtering for electrolyte–insulator–semiconductor (EIS) pH sensors. In this work, the structural properties of Gd 2 Ti 2 O 7 , Er 2 TiO 5 , and Lu 2 Ti 2 O 7 membranes were investigated by X-ray diffraction, atomic force microscopy and X-ray photoelectron spectroscopy. The observed structural properties were then correlated with the resulting pH sensing performances. The EIS device incorporating a Lu 2 Ti 2 O 7 sensing film exhibited a higher sensitivity (59.32 mV pH −1 ), a larger drift rate (0.55 mV h −1 ), a higher hysteresis voltage (5 mV), and a larger hysteresis gap (∼70 mV) compared to those of the other sensing films. This result is attributed to the higher surface roughness and the formation of a thicker interfacial layer at the oxide–Si interface. Furthermore, the impedance effect of EIS sensors has been investigated using capacitance–voltage (C–V) method (frequency-dependent C–V curves). From the impedance spectroscopy analysis, we find that the diameter of a semicircle of an EIS sensor becomes smaller due to a gradual decrease in the bulk resistance of the device with degree of pH value

Interpretation of specific-heat and spontaneous-magnetization anomalies at the reentrant superconducting - ferromagnetic transition in (Ho0.6Er0.4)Rh4B4

International Nuclear Information System (INIS)

Woolf, L.D.; Johnston, D.C.; Mook, H.A.; Koehler, W.C.; Maple, M.B.; Fisk, Z.

1981-09-01

Analysis of neutron-diffraction data on the compound (Ho 0 . 6 Er 0 . 4 )Rh 4 B 4 indicates that the Curie temperature is depressed by about 0.2 K due to the occurrence of superconductivity, in agreement with theoretical predictions. The temperature dependence of the specific heat in the vicinity of the first-order reentrant superconducting - ferromagnetic transition was computed by means of a simple model from the temperature dependence of the spontaneous magnetization of the Ho ions and was found to be in good agreement with the experimental data

Structure, magnetism, and transport of single-crystalline R NiSi3 (R = Y, Gd-Tm, Lu)

Science.gov (United States)

Arantes, Fabiana R.; Aristizábal-Giraldo, Deisy; Masunaga, Sueli H.; Costa, Fanny N.; Ferreira, Fabio F.; Takabatake, Toshiro; Mendonça-Ferreira, Leticie; Ribeiro, Raquel A.; Avila, Marcos A.

2018-04-01

We report on the physical properties of the intermetallic series R NiSi3 (R =Y , Gd-Tm, Lu). High quality single crystals with platelike morphology were grown using the Sn flux method. X-ray powder diffraction data show that this series crystallizes in the orthorhombic space group Cmmm, and Laue patterns indicate that the b axis remains perpendicular to the plane of the plates. Magnetization measurements show anisotropic antiferromagnetic ground states for R = Gd-Tm with Néel temperatures ranging from TN=2.6 K (TmNiSi3) up to 32.2 K (TbNiSi3), as well as metamagnetic transitions that in some cases appear together with hysteresis (TbNiSi3,DyNiSi3, and HoNiSi3). The easy axis changes from a axis to b axis on going from R = Gd-Ho to R = Er-Tm. All transitions from antiferromagnetic to paramagnetic states are clearly marked by sharp peaks in specific heat as well as in the derivative of resistivity measurements, which show metallic temperature dependence for all compounds and residual values in the range of 1 μ Ω cm . DyNiSi3 has two close phase transitions, while HoNiSi3 presents distinct critical temperatures for applied fields in the a or c directions (10.4 and 6.3 K, respectively), pointing to possible component-specific ordering of the local magnetic moments.

Neutron scattering study on R{sub 2}PdSi{sub 3} (R=Ho,Er,Tm) compounds

Energy Technology Data Exchange (ETDEWEB)

Tang, Fei

2010-12-14

Previous studies on the family of inter-metallic rare-earth compounds R{sub 2}PdSi{sub 3} revealed multifaceted magnetic properties, for instance, spin-glass like behavior. Experimental observations include: Signs of a crystallographic superstructure, complicated magnetic structures both in zero field and in applied magnetic fields as well as a generic phase in applied fields for compounds in the series with the heavy rare-earths R=Gd, Tb, Dy, Ho, Er and Tm. This thesis expands the studies on the magnetic properties of R{sub 2}PdSi{sub 3} employing mainly neutron scattering on single crystals with the focus on the compounds with R=Ho, Er and Tm. A detailed analysis of the crystallographic superstructure using modulation wave approach and group theory is presented. The resulting structure implies the existence of two different rare-earth sites with reduced symmetry and an arrangement of the different sites according to sequences as determined by the superstructure. It is shown that the reduced symmetry of the rare-earth sites is explicitly observed in the energy spectra of inelastic neutron scattering. The results on the magnetic structures and excitations are shown and discussed in the framework of the superstructure model. Specifically the generic phase in applied fields is interpreted as a direct consequence of the crystallographic superstructure. It is rather unusual that a crystallographic superstructure is playing such a decisive, and through the field dependence also tunable role in determining the magnetic properties as observed in R{sub 2}PdSi{sub 3}. The mediating interactions between the crystallographic part and the magnetic part of the system are discussed. (orig.)

Miljøundersøgelser ved Kvanefjeldet 2001

DEFF Research Database (Denmark)

Asmund, G.

jordarter' (La Ce Pr Nd Sm Eu Gd Tb Dy Ho Er Tm Yb Lu) Af de mange grundstoffer, der er undersøgt er det kun 'Sjældne jordarter', zirkonium, niobium og thorium, der viser forhøjelser i forhold til baggrundsværdier og samtidigt er stærkt forhøjede i det vand, der siver ud fra minen. Imidlertid fandtes denne...

Study of X-ray L2 absorption edges of Gd, Dy, Ho and Er in metals and compounds

International Nuclear Information System (INIS)

Agarwal, B.K.; Agarwal, B.R.K.

1978-01-01

The positions and shapes of L2 X-ray absorption edges of Gd, Dy, Ho and Er have been studied in metals and in oxides and chlorides, using a forty centimetre bent mica crystal spectrograph. It has been found that the L2 edge shifts towards the high energy side in the compounds and that the chemical shift ΔE depends on the degree of covalency involved. The white line structure at the edge has been analysed in terms of transitions of L2 shell electron to optical nd (n >= 5) states. (author)

Novel Sr{sub 2}LuF{sub 7}–SiO{sub 2} nano-glass-ceramics: Structure and up-conversion luminescence

Energy Technology Data Exchange (ETDEWEB)

Yanes, A.C.; Castillo, J. del, E-mail: fjvargas@ull.edu.es; Luis, D.; Puentes, J.

2016-02-15

Novel transparent nano-glass-ceramics comprising RE-doped Sr{sub 2}LuF{sub 7} nanocrystals have been obtained by thermal treatment of precursor sol–gel glasses. The precipitated Sr{sub 2}LuF{sub 7} nanocrystals with sizes from 4.5 to 11.5 nm, confirmed by X-Ray Diffraction and Transmission Electron Microscopy images, show a cubic phase structure. The luminescent features of Eu{sup 3+} ions, used as structural probes, evidence the distribution of RE ions into the fluoride nanocrystals. Under 980 nm laser excitation, intense UV, vis and NIR up-conversion emissions were observed and studied in Yb{sup 3+}–Tm{sup 3+}, Yb{sup 3+}–Er{sup 3+} and Yb{sup 3+}–Ho{sup 3+} co-doped nano-glass-ceramics. These results suggest considering these nano-glass-ceramics for potential optical applications as high efficient UV up-conversion materials in UV solid state lasers, infrared tuneable phosphors and photonic integrated devices. - Highlights: • Novel sol-gel glass-ceramics with RE{sup 3+}-Sr{sub 2}LuF{sub 7} doped nanocrystals were obtained. • Eu{sup 3+} probe ion was used to distinguish between amorphous and crystalline environments. • The incorporation of an important fraction of RE ions into nanocrystals was confirmed. • Under 980 nm excitation, intense UV-vis-NIR up-conversion emissions were observed.

Harvard ER-2 OH laser-induced fluorescence instrument

Science.gov (United States)

Wennberg, Paul O.; Anderson, James G.

1994-01-01

The Harvard ER-2 OH instrument is scheduled to be integrated into the NASA ER-2 high altitude aircraft ozone payload in August 1992. Design and fabrication is presently underway. This experiment is a descendant of a balloon borne instrument designed and built in the mid-1980s. The ER-2 instrument is being designed to measure OH and HO2 as part of the NASA ozone payload for the investigation of processes controlling the concentration of stratospheric ozone. Although not specifically designed to do so, it is hoped that valid measurements of OH and HO2 can be made in the remote free troposphere with this instrument.

High pressure phase transitions and compressibilities of Er2Zr2O7 and Ho2Zr2O7

Science.gov (United States)

Zhang, F. X.; Lang, M.; Becker, U.; Ewing, R. C.; Lian, J.

2008-01-01

Phase stability and compressibility of rare earth zirconates with the defect-fluorite structure were investigated by in situ synchrotron x-ray diffraction. A sluggish defect-fluorite to a cotunnitelike phase transformation occurred at pressures of ˜22 and ˜30GPa for Er2Zr2O7 and Ho2Zr2O7, respectively. Enhanced compressibility was found for the high pressure phase as a result of increasing cation coordination number and cation-anion bond length.

High Pressure Phase Transitions and Compressibilities of Er2Zr2O7 and Ho2Zr2O7

Energy Technology Data Exchange (ETDEWEB)

Zhang,F.; Lang, M.; Becker, U.; Ewing, R.; Lian, J.

2008-01-01

Phase stability and compressibility of rare earth zirconates with the defect-fluorite structure were investigated by in situ synchrotron x-ray diffraction. A sluggish defect-fluorite to a cotunnitelike phase transformation occurred at pressures of {approx} 22 and {approx} 30 GPa for Er2Zr2O7 and Ho2Zr2O7, respectively. Enhanced compressibility was found for the high pressure phase as a result of increasing cation coordination number and cation-anion bond length.

Crystal Chemistry and Photocatalytic Properties of RE4S4Te3 (RE = Gd, Ho, Er, Tm): Experimental and Theoretical Investigations.

Science.gov (United States)

Chi, Yang; Rong, Liang-Zhen; Suen, Nian-Tzu; Xue, Huai-Guo; Guo, Sheng-Ping

2018-04-25

Reported are the synthesis and structural characterization of a new series of ternary rare-earth mix-chalcogenides RE 4 S 4 Te 3 (RE = Gd, Ho, Er, Tm) that have been obtained from high-temperature solid state reactions. These compounds crystallize in Ho 4 S 4 Te 2.68 structure types with monoclinic C2/ m and/or orthorhombic Immm space groups. The space group variation within this series is due to the position disorder along the Te plane (Te to TeA and TeB). The structural relationship and change between these two space groups are analyzed. It is realized that these compounds are all photocatalytic active under simulated sunlight. The trend of their photocatalytic activities and photocurrent responses is well-explained by using theoretical calculation as well as dipole moment analysis.

Solubility of La, Pr, Eu, Er and Lu in a media of 1M ionic force of NaCl by 303 K

International Nuclear Information System (INIS)

Ramirez G, J.J.; Solache R, M.J.; Jimenez R, M.; Rojas H, A.

2002-01-01

The solubility and the solubility product of La, Pr, Eu, Er and Lu in media of 1M ionic force of NaCl by 303 K was determined, by means of a radiochemical method and the pLn - pCH diagrams in free conditions of CO 2 were constructed. Moreover, the non saturation and the saturated zones and with them the pCH precipitation bound were determined. Finally a comparison among the obtained data in this work and those reported in the literature in several media was realized. (Author)

Double symmetry breaking in TmFe{sub 4}Ge{sub 2} compared to RFe{sub 4}Ge{sub 2} (R=Y, Lu, Er, Ho, Dy) magnetic behaviour

Energy Technology Data Exchange (ETDEWEB)

Schobinger-Papamantellos, P., E-mail: Schobinger@mat.ethz.ch [Laboratory of Crystallography, ETH-Zürich, 8093 Zürich (Switzerland); Buschow, K.H.J. [Van der Waals-Zeeman Institute, University of Amsterdam, NL-1018 XE (Netherlands); Rodríguez-Carvajal, J. [Institut Laue-Langevin, 156X, 38042 Grenoble Cédex (France)

2014-04-15

TmFe4Ge{sub 2} undergoes a double magneto-elastic first order transition at T{sub N},T{sub c} where the high temperature (HT) tetragonal phase disproportionate into two distinct orthorhombic low temperature (LT) phases with commensurate and incommensurate magnetic wave vectors respectively: P4{sub 2}/mnm(HT)T{sub N},T{sub c}→Cmmmq{sub 1}=(0,1/2 ,0)+Pnnm(q{sub 2}=(0,q{sub y},0),q{sub y}≈2/11(LT) Neutron diffraction shows the relative portions of the LT Cmmm and Pnnm competing phases change linearly with T. The amount of the majority HT phase Pnnm (54% at 30 K) decreases linearly to 30% down to 10 K in favour of the Cmmm phase that dominates the range 26–1.5 K. The Tm moments point along the c-axis in both phases while the Fe moments have canted arrangements. The μ{sub Tm}=3.54(3) μ{sub B}/atom at 1.5 K is strongly reduced below the Tm{sup 3+} free ion value g{sub J}J=7 μ{sub B} for the q{sub 1} phase. The q{sub 2} phase corresponds to a 3D canted sinusoidal arrangement. The results are summarised on a phase diagram and compared to the findings in RFe{sub 4}Ge{sub 2} (R=Y, Lu, Er, Ho, Dy) that are reviewed. The multitude of transition paths occurring in those systems arise from the competing magnetoelastic mechanisms involving the R-crystal field anisotropy, the exchange interactions R–R, R–Fe, Fe–Fe of the two sublattices and their coupling to the lattice strain. The geometrical frustration emerging from the compact tetrahedral Fe arrangement with antiferromagnetic interactions leads to 2D and 3D canted, incommensurate and non-magnetic states. The Cmmm transition is triggered by dominating R–R and R–Fe interactions becoming stronger at LT while the Pnnm phase is promoted by Fe–Fe and R–Fe interactions that prevail at HT. Included is also the magnetic structure of the ferromagnetic impurity phase Fe{sub 3}Ge. - Highlights: • Magnetic phase diagram of tetragonal TmFe{sub 4}Ge{sub 2} compound studied by neutron diffraction. • Unusual first

Formation of La3+, Pr3+, Eu3+, Er3+, and Lu3+ complexes with chloride ions, in aqueous medium

International Nuclear Information System (INIS)

Fernandez R, E.; Jimenez R, M.; Solache R, M.

2007-01-01

The constants of stability of the complexes of La 3+ , Pr 3+ , Eu 3+ , Er 3+ , and Lu 3+ with Cl - ions, its were determined, in the aqueous medium of HCI - HClO 4 and by a solvent extraction method. The dinonyl naphtalene sulfonic acid in n-heptane was used as extractant. The lanthanides concentration, it was measured by a VIS spectrophotometry method and by another radiochemical. The ions specific interaction theory (SIT) it was used for the extrapolation to ionic force 0 M. The results indicate that the stability constants of the LnCI 2+ species diminishes when increasing the ion force and the charge density. (Author)

Crystal electric field splitting of R{sup 3+}-ions in pure and Co- and Cu-doped RNi{sub 2}B{sub 2}C (R=Ho, Er, Tm)

Energy Technology Data Exchange (ETDEWEB)

Gasser, U.; Allenspach, P.; Henggeler, W.; Zolliker, M.; Furrer, A. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

1997-09-01

From the crystal-electric-field (CEF) splitting of the R{sup 3+}-ions, the CEF parameters of RNi{sub 2}B{sub 2}C (R=Ho, Er, Tm) were deduced. In order to get information about the influence of the variation of the density of states (DOS) at the Fermi level (E{sub F}), CEF spectroscopy measurements with Co- and Cu-doped ErNi{sub 2}B{sub 2}C-samples were performed. (author) 1 fig., 1 tab., 1 ref.

Rekonstrukce sportovního areálu - zdravotně technické instalace

OpenAIRE

Kohutek, Ivo

2013-01-01

Tato bakalářská práce se zabývá zdravotně technickými instalacemi v čás-ti rekonstruovaného sportovního objektu STARS v městě Třinci. Řešená část objektu je jed-nopodlažní s užitným podzemním podlažím. V teoretické části se věnuje druhům vodovodních armatur a jejich vlivu na úsporu pitné vody. Projektová část následně řeší výpočet, di-menzování vnitřního vodovodu a rozvodů vnitřní kanalizace v rekonstruované části objektu. This bachelor's thesis is focused on medicinal technical instalatio...

Spectral properties and laser performance of Tm, Ho: LuLF4 crystal

Science.gov (United States)

Peng, Haiyan; Zhang, Kun; Zhang, Lianhan; Hang, Yin; Xu, Jianqiu; Tang, Yulong; Cheng, Yan; Xiong, Jing

2008-12-01

LuLiF4 single crystals co-doped with thulium (5%) and holmium (0.5%), which had large size, intact shape and high optical quality, were successfully grown by the medium frequency induction heating Czochralski Technique. The absorption spectrum of the crystals showed that the main absorption peak located at 686 nm and 792nm. At room temperature, LuLiF4 single crystals co-doped with thulium (5%) and holmium (0.5%) were end-pumped by a fiber-coupled laser diode system with pumping wavelength of 795 nm. We achieved power of 50 mw continuous laser output at 2.05 μm wavelength.

Features of proteolytic properties of tetraphenylporphyrin complex with lanthanide group metals

Science.gov (United States)

Tobolkina, Elena A.; Skripnikova, Tatiana A.; Starikova, Anna A.; Shumilova, Galina I.; Pendin, Andrey A.

2018-01-01

Demetallation of metalloporphyrin molecules is one of the essential degradation reactions in photosynthesis. The effect of metalloporphyrin nature on removal of central metals from tetraphenylporphyrin complexes based on lanthanide group metals (Dy, Er, Lu, Ho) has been studied. pH values, at which the metal ions leave the metalloporphyrin complex were established using two-phase spectrophotometric titration with potentiometric pH-control. The pH values decrease with the increase of atomic numbers of lanthanide groups, as well as with increase of 4f-electrons. The reaction of an extra ligand exchange for the hydroxide ion was studied. For Dy-, Er- and Ho-tetraphenylporphyrin complexes one particle of extra ligand coordinates with one porphyrin complex. A complex with dimeric particles can be formed for the system of Lu-tetraphenylporphyrin. Constants of the ion exchange reactions were calculated.

X-ray fluorescence analysis of ytterbium oxide/oxalate for rare earth impurities

International Nuclear Information System (INIS)

Chandola, L.C.; Khanna, P.P.; Thomas, A.

1982-01-01

An XRF method for the determination of Ho, Er, Tm, Lu and Y oxides in Yb 2 O 3 is described. 450 mg sample in the oxalate form is mixed with 150 mg boric acid binding material and pressed into 1.25 inch diameter pellet over a supporting pellet of boric acid. The sample is irradiated by X-rays from a tungsten tube and the fluorescent X-rays are dispersed by a LiF(200) crystal in a Philips PW 1220 semiautomatic X-ray fluorescence spectrometer. The intensities of characteristic X-rays of the impurity elements are measured by a flow proportional counter or a scintillation counter. The lowest determination limit is 0.005% for Ho, Er, Tm and Y and 0.01% for Lu. Calculations for theoretical detection limit, standard deviation and uncertainty are done and presented. (author)

Emission properties of hydrothermal Yb{sup 3+}, Er{sup 3+} and Yb{sup 3+}, Tm{sup 3+}-codoped Lu{sub 2}O{sub 3} nanorods: upconversion, cathodoluminescence and assessment of waveguide behavior

Energy Technology Data Exchange (ETDEWEB)

Barrera, Elixir William; Pujol, MarIa Cinta; DIaz, Francesc [Fisica i Cristal.lografia de Materials, Universitat Rovira i Virgili, Campus Sescelades c/ Marcel.lI Domingo s/n, E-43007 Tarragona (Spain); Choi, Soo Bong; Rotermund, Fabian [Division of Energy Systems Research, Ajou University, 443-749 Suwon (Korea, Republic of); Park, Kyung Ho [Korea Advanced Nano Fab Center, 443-270 Suwon (Korea, Republic of); Jeong, Mun Seok [Advanced Photonics Research Institute, Gwangju Institute of Science and Technology, 500-712 Gwangju (Korea, Republic of); Cascales, Concepcion, E-mail: ccascales@icmm.csic.es [Instituto de Ciencia de Materiales de Madrid, Consejo Superior de Investigaciones CientIficas, c/Sor Juana Ines de la Cruz, 3 Cantoblanco, E-28049 Madrid (Spain)

2011-02-18

Yb{sup 3+} and Ln{sup 3+} (Ln{sup 3+} = Er{sup 3+} or Tm{sup 3+}) codoped Lu{sub 2}O{sub 3} nanorods with cubic Ia3-bar symmetry have been prepared by low temperature hydrothermal procedures, and their luminescence properties and waveguide behavior analyzed by means of scanning near-field optical microscopy (SNOM). Room temperature upconversion (UC) under excitation at 980 nm and cathodoluminescence (CL) spectra were studied as a function of the Yb{sup +} concentration in the prepared nanorods. UC spectra revealed the strong development of Er{sup 3+4}F{sub 9/2} {yields} 4I{sub 15/2} (red) and Tm{sup 3+1}G{sub 4} {yields} {sup 3}H{sub 6} (blue) bands, which became the pre-eminent and even unique emissions for corresponding nanorods with the higher Yb{sup 3+} concentration. Favored by the presence of large phonons in current nanorods, UC mechanisms that privilege the population of {sup 4}F{sub 9/2} and {sup 1}G{sub 4} emitting levels through phonon-assisted energy transfer and non-radiative relaxations account for these observed UC luminescence features. CL spectra show much more moderate development of the intensity ratio between the Er{sup 3+4}F{sub 9/2} {yields}{sup 4}I{sub 15/2} (red) and {sup 2}H{sub 11/2}, {sup 4}S{sub 3/2} {yields} {sup 4}I{sub 15/2} (green) emissions with the increase in the Yb{sup 3+} content, while for Yb{sup 3+}, Tm{sup 3+}-codoped Lu{sub 2}O{sub 3} nanorods the dominant CL emission is Tm{sup 3+1}D{sub 2} {yields} {sup 3}F{sub 4} (deep-blue). Uniform light emission along Yb{sup 3+}, Er{sup 3+}-codoped Lu{sub 2}O{sub 3} rods has been observed by using SNOM photoluminescence images; however, the rods seem to be too thin for propagation of light.

Novel condensation of Au-centered trigonal prisms in rare-earth-metal-rich tellurides: Er7Au2Te2 and Lu7Au2Te2.

Science.gov (United States)

Gupta, Shalabh; Corbett, John D

2010-07-14

A new monoclinic structure occurs for Er(7)Au(2)Te(2) according to X-ray diffraction analysis of single crystals grown at 1200 degrees C: C2/m, Z = 4, a = 17.8310(9) A, b = 3.9819(5) A, c = 16.9089(9) A, beta = 104.361(4) degrees. The isostructural Lu(7)Au(2)Te(2) also exists according to X-ray powder pattern means, a = 17.536(4) A, b = 3.9719(4) A, c = 16.695(2) A, beta = 104.33(1) degrees. The structure contains zigzag chains of condensed, Au-centered tricapped trigonal prisms (TCTP) of Er along c that also share basal faces along b to generate puckered sheets. Further bi-face-capping Er atoms between these generate the three dimensional network along a, with tellurium in cavities outlined by augmented trigonal prismatic Er polyhedra. Bonding analysis via LMTO-DFT methods reveal very significant Er-Au bonding interactions, as quantified by their energy-weighted Hamilton overlap populations (-ICOHP), approximately 49% of the total for all interactions. These and similar Er-Te contributions sharply contrast with the small Er-Er population, only approximately 14% of the total in spite of the high proportion of Er-Er contacts. The strong polar bonding of Er to the electronegative Au and Te leaves Er relatively oxidized, with many of its 5d states falling above the Fermi level and empty. The contradiction with customary representations of structures that highlight rare-earth metal clusters is manifest. The large Er-Au Hamilton overlap population is in accord with the strong bonding between early and late transition metals first noted by Brewer in 1973. The relationship of this structure to the more distorted orthorhombic (Imm2) structure type of neighboring Dy(7)Ir(2)Te(2) is considered.

The possibility of clinical application of the solid state lasers: Nd:YAG, Ho:YAG, and Er:YAG in otolaryngology - head and neck surgery

Science.gov (United States)

Tomaszewska, M.; Kukwa, A.; Tulibacki, M.; Wójtowicz, P.; Olędzka, I.; Jeżewska, E.

2007-02-01

The purpose of this study was to summarize our experiences in clinical application of Nd:YAG, Ho:YAG and Er:YAG in otolaryngology- head and neck surgery. Choosing the laser type and parameters for the particular procedures was based on our previous research on tissue effects of those lasers. During the period of 1993-2006 we performed 3988 surgical procedures with the Nd:YAG laser. Over 87% of those were made for the nasal cavity pathologies as polyps, hyperplasia of inferior nasal turbinate, granulation tissue, postoperative adhesions, vascular malformations, under the local anesthesia conditions. In our experience Nd:YAG laser gives the possibility of good clinical control and low risk of side effects for disorders of high recurrence and frequent interventions necessity, as nasal polyps or respiratory papillomatosis. Nd:YAG assisted uvulopalatoplasty gives an interesting alternative for surgical procedures for snoring and slight/mild OSA-recognized patients. Due to its good hemostatic properties, it is a perfect tool for removal of the chemodectoma from meddle ear. During the period of 1995-2006 we performed 229 surgical procedures with the Ho:YAG laser, mostly for larynx pathologies (adhesion and scar tissue removal). In our experience Ho:YAG laser can serve as a precise laser knife for both soft and bony tissue. The ER:YAG laser still remain under clinical trial. Since 2001 year we performed 24 procedures of removing stone deposits from salivary glands. We believe it may become a promising method to cope with sialolithiasis which allows for glandule function preservation. All of the laser types mentioned above, can be easily coupled with endoscopes, what makes them available for all of the head and necklocalized disorders.

Optical and magneto-optical properties of single crystals of RFe{sub 2} (R = Gd, Tb, Ho, and Lu) and GdCo{sub 2} intermetallic compounds

Energy Technology Data Exchange (ETDEWEB)

Lee, S.J.

1999-02-12

The author has studied the diagonal and off-diagonal optical conductivity of RFe{sub 2}(R = Gd, Tb, Ho, Lu) and GdCo{sub 2} single crystals grown by the flux method. Using spectroscopic ellipsometry the author has measured the dielectric function from 1.5 to 5.5 eV. The magneto-optical Kerr spectrometer at temperatures between 7 and 295 K and applied magnetic fields between 0.5 to 1.6 T. The apparatus and calibration method are described in detail. Using magneto-optical data and optical constants he derives the experimental value of the off-diagonal conductivity components. Theoretical calculations of optical conductivities and magneto-optical parameters were performed using the tight binding-linear muffin tin orbitals method within the local spin density approximation. He applied this TB-LMTO method to LuFe{sub 2}. The theoretical results obtained agree well with the experimental data. The oxidation effects on the diagonal part of the optical conductivity were considered using a three-phase model. The oxidation effects on the magneto-optical parameters were also considered by treating the oxide layer as a nonmagnetic thin transparent layer. These corrections change not only the magnitude but also the shape of the optical conductivity and the magneto-optical parameters.

First-principles calculation of structural and energetic properties for A2Ti2O7 (A = Lu, Er, Y, Gd, Sm, Nd, La)

International Nuclear Information System (INIS)

Zhang, Z.L.; Xiao, H.Y.; Zu, Xiaotao T.; Gao, Fei; Weber, William J.

2009-01-01

A first-principles method has been employed to investigate the structural and energetic properties for A2Ti2O7 (A = Lu, Er, Y, Gd, Sm, Nd, La), including the formation energies of the cation antisite-pair, the anion Frenkel pair that defines anion-disorder, and the coupled cation antisite-pair/anion-Frenkel. It is proposed that the interaction may have more significant influence on the radiation resistance behavior of titanate pyrochlores, although the interactions are relatively much stronger than the interactions. It is found that the defect formation energies are not simple functions of the A-site cation radii. The formation energy of the cation antisite-pair increases continuously as the A-site cation varies from Lu to Gd, and then decreases continuously with the variation of the A-site cation from Gd to La, in excellent agreement with the radiation-resistance trend of the titanate pyrochlores. The band gaps in these pyrochlores were also measured, and the band gap widths changed continuously with cation radius.

Experimental demonstration of an Er-doped fiber ring laser mode-locked with a Tm–Ho co-doped fiber saturable absorber

International Nuclear Information System (INIS)

Tao, Mengmeng; Wu, Junjie; Wu, Yong; Yang, Pengling; Ye, Xisheng; Peng, Junsong

2013-01-01

Mode-locking operation of an Er-doped fiber laser with a Tm–Ho co-doped fiber saturable absorber is demonstrated for the first time. Q-switching, Q-switched mode-locking and CW mode-locking operation modes are observed sequentially with increase of the pump power. In the mode-locking operation mode, a repetition rate at the fundamental cavity frequency of 9.05 MHz is obtained with a pulse duration of 46.3 ns. By rotating the polarization controller, a repetition rate up to 887 MHz is achieved, and the pulse duration is shortened to 0.548 ns. (paper)

New anisotropic rare earth fluorides BaR2F8(R=Y,Dy-Lu): growth and characterization

International Nuclear Information System (INIS)

Kaminskii, A.A.; Butashin, A.V.; Sulyanov, S.N.; Bagayev, S.N.; Eichler, H.J.; Findeisen, J.; Liu, B.; Taeuber, U.; Peuser, P.

1998-01-01

Polymorphism of BaR 2 F 8 compounds is analyzed, and some peculiarities of the crystal growth from the melt are discussed. We report on the orthorhombic BaLu 2 F 8 crystal with ordered structure, a new crystalline material for generating Ln 3+ activator ions. Spectroscopic and laser characteristics of Nd 3+ - and Er 3+ -doped BaLu 2 F 8 samples are discussed as representative examples. Besides, we pay special attention to monoclinic BaY 2 F 8 :Er 3+ crystals, as active media for highly efficient CW 3 μm laser-diode pumped lasers. (orig.)

Konstrukce vřeten vícevřetenového soustružnického automatu

OpenAIRE

Kráčmar, Tomáš

2016-01-01

Obsahem diplomové práce je konstrukce vřeten vícevřetenového soustružnického automatu pro práci z tyče maximálního průměru 7 mm. Práce se zabývá novou koncepcí pohonu vřeten, kde jsou vřetena poháněna externími asynchronními motory přes ozubená kola s vnitřním ozubením uložená vně vřetenového bubnu namísto současného způsobu pohonu centrálními koaxiálními hřídeli. Součástí práce je rešerše vícevřetenových automatů včetně popisu hlavních uzlů, konstrukční návrh, pevnostní výpočty, výpočty trva...

The lanthanoid(III) chloride oxoselenates(IV) MCl[SeO3] (M = Sm - Lu) with HoCl[TeO3]- or B-type structure

International Nuclear Information System (INIS)

Lipp, C.; Schleid, T.

2008-01-01

The B-type lanthanoid(III) chloride oxoselenates(IV) MCl[SeO 3 ] (M = Sm - Lu) crystallize in the orthorhombic space group Pnma (no. 62) with Z = 4 in the structure type of HoCl[TeO 3 ]. Their lattice constants are decreasing following the lanthanoid contraction from a = 730.01(7), b = 707.90(7), c 895.64(9) pm for SmCl[SeO 3 ] to a = 714.63(7), b = 681.76(7), c = 864.05(9) pm for LuCl[SeO 3 ]. In contrast to NdCl[SeO 3 ], the only representative of the A-type structure, where the coordination numbers of the Nd 3+ cations are 7+2 and 8, the B-type structure is dominated by pentagonal bipyramids [MO 5 Cl 2 ] 9- (CN(M 3+ ) = 7), which are connected via trans-oriented O..O edges to ∞ 1 {[MO 4/2 e O 1/1 t Cl 2/1 t ] 5- } chains (e = edge-sharing, t = terminal) running parallel to the [010] direction. Their inclination relative to each other allows for an alternating interconnection of these chains via Cl - and ψ 1 -tetrahedral [SeO 3 ] 2- anions to form a three-dimensional structure. The distances within the [SeO 3 ] 2- groups are in the normal range (d(Se-O) = 165 - 172 pm), while those of the O 2- and Cl - anions to the central M 3+ cation diminish in dependence of the increasing atomic number (d(M-O) = 226 - 244 pm / 216 - 232 pm, d(M-Cl) 277 - 278 pm / 266 - 270 pm, M = Sm / Lu). For the synthesis of the chloride oxoselenates(IV) MCl[SeO 3 ] the respective lanthanoid sesquioxide (M 2 O 3 ) and selenium dioxide (SeO 2 ) were reacted with either an eutectic mixture of RbCl and LiCl or with the corresponding lanthanoid trichloride (MCl 3 ) in evacuated silica ampoules for either five weeks at 500 C or one week at 850 C. (orig.)

Synthesis under ambient pressure and tri-axial magnetic orientation in REBa2Cu4O8 (RE = Y, Sm, Eu, Gd, Dy, Ho, Er)

International Nuclear Information System (INIS)

Yamaki, M.; Horii, S.; Haruta, M.; Maeda, T.; Shimoyama, J.

2011-01-01

REBa 2 Cu 4 O 8 (RE124) was synthesized by a flux method in ambient pressure for RE = Y, Sm, Eu, Gd, Dy, Ho and Er. Tri-axial orientation of RE124 was achieved in a modulated rotating magnetic field of 10 T. Orientation axes in RE124 depended on the type of RE. Magnetization axes were determined from magnetic anisotropies of Cu and RE ions. We report the rare-earth (RE)-dependent magnetization axes of REBa 2 Cu 4 O 8 , which was synthesized by a flux method under ambient pressure, using powder samples tri-axially oriented in a modulated rotating magnetic field of 10 T. By optimizing the growth temperature and cooling rate, RE124 crystals were successfully grown for RE = Y, Sm, Eu, Gd, Dy, Ho, and Er. From the X-ray diffraction measurement, the magnetically oriented directions were largely dependent on the type of RE ions of RE124. However, the tri-axial magnetic anisotropies of RE124 could be qualitatively understood in terms of the magnitude relation between the single-ion magnetic anisotropy of RE 3+ ions and the magnetic anisotropy generated by the CuO 2 plane and Cu-O chain. For the practical use of this magneto-scientific process, the control of magnetization axes and tri-axial magnetic anisotropies through crystallochemical control is indispensable.

Formation of La{sup 3+}, Pr{sup 3+}, Eu{sup 3+}, Er{sup 3+}, and Lu{sup 3+} complexes with chloride ions, in aqueous medium; Formacion de complejos de La{sup 3+}, Pr{sup 3+}, Eu{sup 3+}, Er{sup 3+} y Lu{sup 3+} con iones cloruro, en medio acuoso

Energy Technology Data Exchange (ETDEWEB)

Fernandez R, E.; Jimenez R, M.; Solache R, M. [ININ, 52750 La Marquesa, Estado de Mexico (Mexico)

2007-07-01

The constants of stability of the complexes of La{sup 3+}, Pr{sup 3+}, Eu{sup 3+}, Er{sup 3+}, and Lu{sup 3+} with Cl{sup -} ions, its were determined, in the aqueous medium of HCI - HClO{sub 4} and by a solvent extraction method. The dinonyl naphtalene sulfonic acid in n-heptane was used as extractant. The lanthanides concentration, it was measured by a VIS spectrophotometry method and by another radiochemical. The ions specific interaction theory (SIT) it was used for the extrapolation to ionic force 0 M. The results indicate that the stability constants of the LnCI{sup 2+} species diminishes when increasing the ion force and the charge density. (Author)

Crystal structure of 4-RbHo(PO3)4, 4-RbTm(PO3)4 and 4-CsEr(PO3)4

International Nuclear Information System (INIS)

Maksimova, S.I.; Palkina, K.K.; Chibiskova, N.T.

1982-01-01

X-ray structural study of 4-RbLn(PO 3 ) 4 (Ln=Mo, Tm) and 4-CsEr(PO 3 ) 4 is carried out. The compounds are crystallized in monoclinic crystal system, sp. gr P2 1 /n. Parameters of their unit cell, atom coordinates, anisotropic heat parameters, interatomic distances and valent angles are given. 4-RbHo(PO 3 ) 4 , 4-RbTm(PO 3 ) 4 , 4-CsEr(PO 3 ) 4 are isostructural to previously studied TlNd(PO 3 ) and 4-RbNd(PO 3 ) 4 . Using as an example the structural type 4-M 1 Ln(PO 3 ) 4 it is shown that the change of the shortest distances Ln-Ln, M 1 -M 1 and M 1 -Ln, as well as of degree of polymorphous chain corrugation to a higher extent depends on rare earth atom dimensions, than on monovalent metal ion dimensions [ru

Magnetic ordering of Hf{sub 3}Ni{sub 2}Si{sub 3}-type {Sm, Tb, Er}{sub 3}Co{sub 2}Ge{sub 3} and {Tb, Ho}{sub 3}Ni{sub 2}Ge{sub 3} compounds

Energy Technology Data Exchange (ETDEWEB)

Morozkin, A.V., E-mail: morozkin@tech.chem.msu.ru [Department of Chemistry, Moscow State University, Leninskie Gory, House 1, Building 3, Moscow, GSP-1, 119991 (Russian Federation); Yapaskurt, V.O. [Department of Petrology, Geological Faculty Moscow State University, Leninskie Gory, Moscow 119991 (Russian Federation); Nirmala, R. [Indian Institute of Technology Madras, Chennai 600036 (India); Quezado, S.; Malik, S.K. [Departamento de Física Teórica e Experimental, Universidade Federal do Rio Grande do Norte, Natal 59082-970 (Brazil); Mozharivskyj, Y. [Department of Chemistry and Chemical Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4M1 (Canada); Isnard, O. [CNRS, Institut. Néel, 25 rue des Martyrs BP166 x, F-38042 Grenoble (France); Université Grenoble Alpes, Inst. Néel, F-38042 Grenoble (France)

2017-02-15

The magnetic ordering of Hf{sub 3}Ni{sub 2}Si{sub 3}-type {Sm, Tb, Er}{sub 3}Co{sub 2}Ge{sub 3} and {Tb, Ho}{sub 3}Ni{sub 2}Ge{sub 3} compounds (space group Cmcm, oC32) was investigated via magnetization measurements and neutron diffraction study in a zero-applied field. {Sm, Tb, Er}{sub 3}Co{sub 2}Ge{sub 3} and Ho{sub 3}Ni{sub 2}Ge{sub 3} exhibit field sensitive complex antiferromagnetic orderings with T{sub N}=51 K, T{sub m}=10 K for Sm{sub 3}Co{sub 2}Ge{sub 3}, T{sub N}=34 K, T{sub m}=13 K for Tb{sub 3}Co{sub 2}Ge{sub 3}, T{sub N}=7 K for Er{sub 3}Co{sub 2}Ge{sub 3} and T{sub N}=11 K for Ho{sub 3}Ni{sub 2}Ge{sub 3}. At 2 K and above the critical field of ~5 kOe, 20 kOe, 4 kOe and 7 kOe for Sm{sub 3}Co{sub 2}Ge{sub 3}, Tb{sub 3}Co{sub 2}Ge{sub 3}, Er{sub 3}Co{sub 2}Ge{sub 3} and Ho{sub 3}Ni{sub 2}Ge{sub 3}, respectively, saturation magnetizations per rare-earth atom are 6.5 μ{sub B} for Tb{sub 3}Co{sub 2}Ge{sub 3}, 7.0 μ{sub B} for Er{sub 3}Co{sub 2}Ge{sub 3} and 8.0 μ{sub B} for Ho{sub 3}Ni{sub 2}Ge{sub 3} in the field of 140 kOe, whereas magnetization of Sm{sub 3}Co{sub 2}Ge{sub 3} has an antiferromagnetic behaviour. The isothermal magnetic entropy change, ΔS{sub m}, indicates a field-induced ferromagnetic ordering in Sm{sub 3}Co{sub 2}Ge{sub 3}, Tb{sub 3}Co{sub 2}Ge3, Er{sub 3}Co{sub 2}Ge{sub 3} and Ho{sub 3}Ni{sub 2}Ge{sub 3} with a maximal ΔS{sub m} value of −10.9 J/kg K for Ho{sub 3}Ni{sub 2}Ge{sub 3} at 11 K for a field change of 50 kOe. In a zero-applied magnetic field, below T{sub N}=33 K and down to T{sub m}{sup ND}=15 K Tb{sub 3}Ni{sub 2}Ge{sub 3} shows an ac-antiferromagnetic ordering with the C2′/c magnetic space group, a K{sub 0}=[0, 0, 0] propagation vector and a a{sub Tb3Ni2Ge3}×b{sub Tb3Ni2Ge3}×c{sub Tb3Ni2Ge3} magnetic unit cell. Below T{sub m}{sup ND}=15 K, its magnetic structure is a sum of the ac-antiferromagnetic component with the C2′/c magnetic space group of the K{sub 0} vector and a sine-modulated a

Influence of Al-atoms on the spin fluctuation scattering in R(Co,Al)2 compounds

International Nuclear Information System (INIS)

Duc, N.H.; Hung, D.T.; Kim-Ngan, N.H.; Sechovsky, V.

1992-01-01

The resistivity and magnetisation have been measured for the R(Co 1-x Al x ) 2 compounds with R=Nd, Gd, Tb, Dy, Ho, Er and Lu. For x=0.2 the resistivity enhancement is observed below T c , however, for the compounds with R=Lu-Tb only. The results are discussed in terms of the spin fluctuation scattering and indicate that the enhancement of the spin fluctuation scattering is strongly related to the lattice parameter. (orig.)

Features of magnetic and thermal properties of R(Co{sub 1−x}Fe{sub x}){sub 2} (x≤0.16) quasibinary compounds with R=Dy, Ho, Er

Energy Technology Data Exchange (ETDEWEB)

Anikin, Maksim; Tarasov, Evgeniy; Kudrevatykh, Nikolay [Institute of Natural Sciences, Ural Federal University, Ekaterinburg 620002 (Russian Federation); Inishev, Aleksander [Institute of Metal Physics, Ekaterinburg 620137 (Russian Federation); Semkin, Mikhail; Volegov, Aleksey; Zinin, Aleksander [Institute of Natural Sciences, Ural Federal University, Ekaterinburg 620002 (Russian Federation)

2016-11-15

In this work the results of measurements of high field susceptibility, paraprocess susceptibility and thermal properties of R(Co{sub 1−x}Fe{sub x}){sub 2} intermetallic compounds (R=Dy, Ho, Er and x=(0−0.16)) are presented (heat capacity and magnetocaloric effect (MCE)). A magnetic structure of the Ho(Co{sub 0.88}Fe{sub 0.12}){sub 2} at 293 K and 78 K was studied by neutron powder diffraction. Some peculiarities of a high-field susceptibility were revealed at low temperatures and around the Curie point (T{sub C}). In temperature range lower than T{sub C} by (100–150) K, magnetic contributions to a zero-field heat capacity were found. Studying MCE in wide temperatures range, the large change of the entropy magnetic contribution (∆S) was observed which correlates with ∆T phenomenon. In particular, for the Er(Co{sub 0.84}Fe{sub 0.16}){sub 2} compound the ∆S value at low temperatures is six times higher than that at Curie point. The possible reasons of such behavior were discussed. - Highlights: • Magnetic and magnetocaloric properties of R(Co–Fe){sub 2} compounds have been studied. • Fe introduction induces the disorientation effect in Ho-ions magnetic ordering. • Emergence of magnetic contribution to a heat capacity at temperatures less T{sub C}. • The existence of a broad maximum on a temperature dependence of the MCE. • Direct MCE measurements at magnetic field of (0–17.5) kOe have been performed.

In situ measurements of HO{sub x} in super- and subsonic aircraft exhaust plumes

Energy Technology Data Exchange (ETDEWEB)

Hanisco, T F; Wennberg, P O; Cohen, R C; Anderson, J G [Harvard Univ., Cambridge, MA (United States). Dept. of Chemistry; Fahey, D W; Keim, E R; Gao, R S; Wamsley, R C; Donnelly, S G; Del Negro, L A [National Oceanic and Atmospheric Administration, Boulder, CO (United States). Aeronomy Lab.; others, and

1998-12-31

Concentrations of HO{sub x} (OH and HO{sub 2}) have been obtained in the exhaust plumes of an Air France Concorde and a NASA ER-2 in the lower stratosphere and the NASA DC-8 in the upper troposphere using instruments aboard the NASA ER-2. These fast-time response in situ measurements are used in conjunction with simultaneous in situ measurements of other key exhaust species (NO, NO{sub 2}, NO{sub y}, H{sub 2}O, and CO) to analyze the emissions of HO{sub x} from each aircraft under a variety of conditions. The data are used to establish a general description of gas phase plume chemistry that is easily implemented in a photochemical model. This model is used to determine the amount of HO{sub x} emitted from the engines and the gas phase oxidation rates of nitrogen and sulfur species in the exhaust plumes. (author) 10 refs.

In situ measurements of HO{sub x} in super- and subsonic aircraft exhaust plumes

Energy Technology Data Exchange (ETDEWEB)

Hanisco, T.F.; Wennberg, P.O.; Cohen, R.C.; Anderson, J.G. [Harvard Univ., Cambridge, MA (United States). Dept. of Chemistry; Fahey, D.W.; Keim, E.R.; Gao, R.S.; Wamsley, R.C.; Donnelly, S.G.; Del Negro, L.A. [National Oceanic and Atmospheric Administration, Boulder, CO (United States). Aeronomy Lab.; and others

1997-12-31

Concentrations of HO{sub x} (OH and HO{sub 2}) have been obtained in the exhaust plumes of an Air France Concorde and a NASA ER-2 in the lower stratosphere and the NASA DC-8 in the upper troposphere using instruments aboard the NASA ER-2. These fast-time response in situ measurements are used in conjunction with simultaneous in situ measurements of other key exhaust species (NO, NO{sub 2}, NO{sub y}, H{sub 2}O, and CO) to analyze the emissions of HO{sub x} from each aircraft under a variety of conditions. The data are used to establish a general description of gas phase plume chemistry that is easily implemented in a photochemical model. This model is used to determine the amount of HO{sub x} emitted from the engines and the gas phase oxidation rates of nitrogen and sulfur species in the exhaust plumes. (author) 10 refs.

Evaluation of the 175Lu(n,2n)174Lu, 175Lu(n,2n/sup 174m/Lu, and 175Lu(n,3n)173Lu cross sections from threshold to 20 MeV

International Nuclear Information System (INIS)

Philis, C.; Young, P.G.; Arthur, E.D.

1978-04-01

An evaluation of the 175 Lu(n,2n) 174 Lu, 175 Lu(n,2n)/sup 174m/Lu, and 175 Lu(n,3n) 173 Lu reactions from threshold to 20 MeV is presented. Available experimental data were renormalized to a consistent set of standards and were used along with results from statistical-preequilibrium model calculations to produce recommended curves for each of these reactions

Hexagonal perovskites with cationic vacancies. 33. Compounds of type Ba/sub 6-x/Sr/sub x/B/sub 2-y//sup 3 +/SE/sub y//sup 3 +/W/sub 3/vacantO/sub 18/

Energy Technology Data Exchange (ETDEWEB)

Lindner, I; Kemmler-Sack, S [Tuebingen Univ. (Germany, F.R.). Lehrstuhl fuer Anorganische Chemie 2

1982-12-01

In the series Ba/sub 6-x/Sr/sub x/Lu/sub 2-y/SE/sub y//sup 3 +/W/sub 3/vacantO/sub 18/ a substitution of Sr/sup 2 +/ for Ba/sup 2 +/ is possible. According to intensity calculations on powder data of BaSr/sub 5/Lu/sub 1.6/Ho/sub 0.4/W/sub 3/vacantO/sub 18/ the compounds crystallize in a rhombohedral 18 L type with the sequence (hhccc)/sub 3/; space group R-3m. The refined, intensity related R' value is 11.5%. The differences in properties (diffuse reflectance spectra, photoluminescence) between the hexagonal modifications Ba/sub 6/B/sub 2-y//sup 3 +/SE/sub y//sup 3 +/W/sub 3/vacantO/sub 18/ (B/sup 3 +/ = Gd, Y, Lu; SE/sup 3 +/ = Sm, Eu, Tb, Dy, Ho, Er, Tm) and the corresponding cubic HT modifications are discussed.

Investigation of thermal expansion and compressibility of rare-earth orthovanadates using a dielectric chemical bond method.

Science.gov (United States)

Zhang, Siyuan; Zhou, Shihong; Li, Huaiyong; Li, Ling

2008-09-01

The chemical bond properties, lattice energies, linear expansion coefficients, and mechanical properties of ReVO 4 (Re = La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, Sc, Y) are investigated systematically by the dielectric chemical bond theory. The calculated results show that the covalencies of Re-O bonds are increasing slightly from La to Lu and that the covalencies of V-O bonds in crystals are decreasing slightly from La to Lu. The linear expansion coefficients decrease progressively from LaVO 4 to LuVO 4; on the contrary, the bulk moduli increase progressively. Our calculated results are in good agreement with some experimental values for linear expansion coefficients and bulk moduli.

Monodisperse and core-shell structured SiO{sub 2}-Lu{sub 2}O{sub 3}:Ln{sup 3+} (Ln=Eu, Tb, Dy, Sm, Er, Ho, and Tm) spherical particles: A facile synthesis and luminescent properties

Energy Technology Data Exchange (ETDEWEB)

Xu, Zhenhe, E-mail: xuzh056@163.com [College of Applied Chemistry, Shenyang University of Chemical Technology, Shenyang 100142 (China); Feng, Bin [China National Aviation Fuel Group Corporation, Planning and Development Department, Beijing 100088 (China); Bian, Shasha; Liu, Tao; Wang, Mingli; Gao, Yu; Sun, Di; Gao, Xin [College of Applied Chemistry, Shenyang University of Chemical Technology, Shenyang 100142 (China); Sun, Yaguang, E-mail: yaguangsun@yahoo.com.cn [College of Applied Chemistry, Shenyang University of Chemical Technology, Shenyang 100142 (China)

2012-12-15

The core-shell structured SiO{sub 2}-Lu{sub 2}O{sub 3}:Ln{sup 3+} particles were realized by coating the Lu{sub 2}O{sub 3}:Ln{sup 3+} phosphors onto the surface of non-aggregated, monodisperse and spherical SiO{sub 2} particles by the Pechini sol-gel method. The as-synthesized products were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), energy-dispersive X-ray (EDX) spectra, scanning electron microscopy (SEM), transmission electron microscopy (TEM), high-resolution transmission electron microscopy (HRTEM), photolumiminescence (PL), and low-voltage cathodoluminescence (CL). The results indicate that the 800 Degree-Sign C annealed sample consists of crystalline Lu{sub 2}O{sub 3} shells and amorphous SiO{sub 2} cores, in spherical shape with a narrow size distribution. The as-obtained particles show strong light emission with different colors corresponding to different Ln{sup 3+} ions under ultraviolet-visible light excitation and low-voltage electron beams excitation, which have potential applications in fluorescent lamps and field emission displays. - Graphical Abstract: Representative SEM and TEM images of the core-shell structured SiO{sub 2}-Lu{sub 2}O{sub 3}:Eu{sup 3+} particles; CIE chromaticity diagram showing the emission colors for SiO{sub 2}-Lu{sub 2}O{sub 3}:Ln{sup 3+}; Multicolor emissions of SiO{sub 2}-Lu{sub 2}O{sub 3}:Ln{sup 3+} particles. Highlights: Black-Right-Pointing-Pointer The core-shell particles were realized by coating the phosphors onto the surface of SiO{sub 2} particles. Black-Right-Pointing-Pointer The sample consists of crystalline Lu{sub 2}O{sub 3} shells and amorphous SiO{sub 2} cores. Black-Right-Pointing-Pointer The particles show different light emission colors corresponding to Ln{sup 3+} ions. Black-Right-Pointing-Pointer They have potential applications in fluorescent lamps and field emission displays.

High-gain polymer optical waveguide amplifiers based on core-shell NaYF4/NaLuF4: Yb3+, Er3+ NPs-PMMA covalent-linking nanocomposites

Science.gov (United States)

Zhang, Meiling; Zhang, Weiwei; Wang, Fei; Zhao, Dan; Qu, Chunyang; Wang, Xibin; Yi, Yunji; Cassan, Eric; Zhang, Daming

2016-11-01

Waveguide amplifiers have always been significant key components for optical communication. Unfortunately, the low concentration of rare earth ions doped in the host material and the inadequate optimization of the waveguide structure have been the common bottleneck limitations. Here, a novel material, NaYF4/NaLuF4: 20% Yb3+, 2% Er3+ nanoparticle-Polymeric Methyl Methacrylate covalent-linking nanocomposite, was synthesized. The concentrations of Er3+ and Yb3+ doping increased an order of magnitude. Under a 980 nm laser excitation, highly efficient emission at 1.53 μm was obtained. The characteristic parameters of the single mode waveguide were carefully designed and optimized by using a finite difference method. A formulized iteration method is presented for solving the rate equations and the propagation equations of the EYCDWA, and both the steady state behavior and the gain were numerically simulated. The optimal Er3+ and Yb3+ concentrations are 2.8 × 1026 m-3 and 2.8 × 1027 m-3, and the optimal waveguide length is 1.3 cm. Both theoretical and experimental results indicated that, for an input signal power of 0.1 mW and a pump power of 400 mW, a net gain of 15.1 dB at 1530 nm is demonstrated. This result is the highest gain ever reported in polymer-based waveguide amplifiers doped with inorganic Er3+-Yb3+ codoped nanocrystals.

First principle studies of electronic and magnetic properties of Lanthanide-Gold (RAu) binary intermetallics

Energy Technology Data Exchange (ETDEWEB)

Ahmad, Sardar [Center for Computational Materials Science, University of Malakand, Chakdara, 18800 Pakistan (Pakistan); Department of Chemistry, University of Malakand, Chakdara, 18800 Pakistan (Pakistan); Ahmad, Rashid, E-mail: rashmad@gmail.com [Center for Computational Materials Science, University of Malakand, Chakdara, 18800 Pakistan (Pakistan); Department of Chemistry, University of Malakand, Chakdara, 18800 Pakistan (Pakistan); Jalali-Asadabadi, S. [Department of Physics, Faculty of Sciences, University of Isfahan (UI), Hezar Gerib Avenue, Isfahan 81746-73441 (Iran, Islamic Republic of); Ali, Zahid [Center for Computational Materials Science, University of Malakand, Chakdara, 18800 Pakistan (Pakistan); Department of Physics, University of Malakand, Chakdara, 18800 Pakistan (Pakistan); Ahmad, Iftikhar [Center for Computational Materials Science, University of Malakand, Chakdara, 18800 Pakistan (Pakistan); Vice Chancellor, Abbott Abad University of Science and Technology, Abbott Abad (Pakistan)

2017-01-15

In this article we explore the electronic and magnetic properties of RAu intermetallics (R=Ce, Pr, Nd, Sm, Gd, Tb, Dy, Ho, Er, Tm, Yb and Lu) for the first time. These properties are calculated by using GGA, GGA+U and hybrid density functional theory (HF) approaches. Our calculations show that HF provides superior results, consistent to the experimentally reported data. The chemical bonding between rare-earth and gold atoms within these compounds are explained on the basis of spin dependent electronic clouds in different planes, which shows predominantly ionic and metallic nature between Au and R atoms. The Cohesive energies of RAu compounds show direct relation with the melting points. Spin-dependent electronic band structure demonstrates that all these compounds are metallic in nature. The magnetic studies show that HoAu and LuAu are stable in non-magnetic structure, PrAu is stable in ferromagnetic phase and CeAu, NdAu, SmAu, GdAu, TbAu, DyAu, ErAu, TmAu, YbAu are anti-ferromagnetic materials.

Spin reorientation behavior in Yb doped YMnO3

International Nuclear Information System (INIS)

Sharma, Neetika; Das, A.

2014-01-01

RMnO 3 with smaller rare-earths ions (R = Ho to Lu and Y) crystallize in the non-centrosymmetric hexagonal space group P6 3 cm. The magnetic structure of RMnO 3 compounds with (R=Er,Yb.Lu) are described by irreducible representations (IR) Γ 2,4 and Γ 1,3 for those with higher ionic radii (R=Ho,Y,Y-Er). Of recent the magnetic structure of YMnO 3 has been found to be better described by Γ 3 + Γ 4 IR. YbMnO 3 is another hexagonal manganite, with almost similar transition temperature, and basically shares all the physical properties of YMnO 3 , except for the magnetic structure. The magnetic structure of YbMnO 3 can be explained by Γ 2 or Γ 4 . The non collinear nature of magnetic ordering in these compounds arises due to the frustration inherent in these compounds. In this study we have probed the effect of a magnetic ion (Yb) on the magnetic structure of these frustrated isostructural compounds

General synthesis and structural evolution of a layered family of Ln8(OH)20Cl4 x nH2O (Ln = Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, and Y).

Science.gov (United States)

Geng, Fengxia; Matsushita, Yoshitaka; Ma, Renzhi; Xin, Hao; Tanaka, Masahiko; Izumi, Fujio; Iyi, Nobuo; Sasaki, Takayoshi

2008-12-03

The synthesis process and crystal structure evolution for a family of stoichiometric layered rare-earth hydroxides with general formula Ln(8)(OH)(20)Cl(4) x nH(2)O (Ln = Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, and Y; n approximately 6-7) are described. Synthesis was accomplished through homogeneous precipitation of LnCl(3) x xH(2)O with hexamethylenetetramine to yield a single-phase product for Sm-Er and Y. Some minor coexisting phases were observed for Nd(3+) and Tm(3+), indicating a size limit for this layered series. Light lanthanides (Nd, Sm, Eu) crystallized into rectangular platelets, whereas platelets of heavy lanthanides from Gd tended to be of quasi-hexagonal morphology. Rietveld profile analysis revealed that all phases were isostructural in an orthorhombic layered structure featuring a positively charged layer, [Ln(8)(OH)(20)(H(2)O)(n)](4+), and interlayer charge-balancing Cl(-) ions. In-plane lattice parameters a and b decreased nearly linearly with a decrease in the rare-earth cation size. The interlamellar distance, c, was almost constant (approximately 8.70 A) for rare-earth elements Nd(3+), Sm(3+), and Eu(3+), but it suddenly decreased to approximately 8.45 A for Tb(3+), Dy(3+), Ho(3+), and Er(3+), which can be ascribed to two different degrees of hydration. Nd(3+) typically adopted a phase with high hydration, whereas a low-hydration phase was preferred for Tb(3+), Dy(3+), Ho(3+), Er(3+), and Tm(3+). Sm(3+), Eu(3+), and Gd(3+) samples were sensitive to humidity conditions because high- and low-hydration phases were interconvertible at a critical humidity of 10%, 20%, and 50%, respectively, as supported by both X-ray diffraction and gravimetry as a function of the relative humidity. In the phase conversion process, interlayer expansion or contraction of approximately 0.2 A also occurred as a possible consequence of absorption/desorption of H(2)O molecules. The hydration difference was also evidenced by refinement results. The number of coordinated water

Phase diagram with an enhanced spin-glass region of the mixed Ising-XY magnet LiHo_xEr_1-xF₄

DEFF Research Database (Denmark)

Piatek, J. O.; Dalla Piazza, B.; Nikseresht, N.

2013-01-01

We present the experimental phase diagram of LiHoxEr1-xF4, a dilution series of dipolar-coupled model magnets. The phase diagram was determined using a combination of ac susceptibility and neutron scattering. Three unique phases in addition to the Ising ferromagnet LiHoF4 and the XY antiferromagn...

Synthesis of Halide- and Solvent free metal borohydrides

DEFF Research Database (Denmark)

Grinderslev, Jakob; Møller, Kasper Trans; Jensen, Torben René

chloride or LiBH4 is present in the sample. The synthesis pathway has been shown to work for most of the already known metal borohydrides, M = Na, Ca, Sr, Ba, Y, La, Eu, Gd, Tb, Dy, Ho, Er, Tm, and Yb, but also new borohydrides are formed, M = Pr, Nd and Lu. Besides new compounds, new polymorphs...

Dy163-Ho163 branching: an s-process barometer

International Nuclear Information System (INIS)

Beer, H.; Walter, G.; Macklin, R.L.

1984-01-01

The neutron capture cross sections of Dy163 and Er164 have been measured to analyze the s-process branching at Dy163-Ho163. The reproduction of the s-process abundance of Er164 via this branching is sensitive to temperature kT, neutron density, and electron density n/sub e/. The calculations using information from other branchings on kT and the neutron density n/sub n/ give constraints for n/sub e/ at the site of the s-process

Electronic and crystal structure, EPR and magnetic investigations of YF{sub 3}:1%RE (RE = Pr, Ho, Er and Tm) and LaF{sub 3}:1%Pr nanocrystals

Energy Technology Data Exchange (ETDEWEB)

Talik, E., E-mail: talik@us.edu.pl [Institute of Physics, University of Silesia, ul. Uniwersytecka 4, 40-007 Katowice (Poland); Zajdel, P.; Guzik, A.; Skrzypek, D. [Institute of Physics, University of Silesia, ul. Uniwersytecka 4, 40-007 Katowice (Poland); Lipińska, L.; Michalska, M. [Institute of Electronic Materials Technology, ul. Wólczyńska 133, 01-919 Warszawa (Poland)

2014-12-15

Highlights: • The thermal decomposition method was successfully applied for the first time in order to obtain the good quality nanocrystals of YF{sub 3}:1%RE. • For YF{sub 3}:1%Pr and LaF{sub 3}:1%Pr extra phase PrF{sub 3} was found. • The XPS energy gap is about 10 eV. • Surface contamination can be responsible for the deterioration of the optical properties of the composites. - Abstract: A new chemical synthesis route by a thermal decomposition of nitrates and acetates, preceded by solution displacement reaction, was successfully applied to obtain the YF{sub 3}:1%RE (RE = Pr, Ho, Er and Tm) and LaF{sub 3}:1%Pr nanocrystals. The samples were characterized by the following methods: X-ray diffraction, scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), magnetic susceptibility thermal dependence measurements and electron paramagnetic resonance (EPR). The obtained YF{sub 3}:1%RE (RE = Pr, Ho, Er and Tm) materials crystallized with orthorhombic symmetry, whilst LaF{sub 3}:1%Pr exhibits hexagonal structure. Chemical composition determined by EDX, XPS and magnetic measurements was close to nominal formula. SEM images show the nanometric size of the grains. Surface contamination can be suggested to be responsible for the deterioration of the optical properties of the composites.

Separation and Recycling for Rare Earth Elements by Homogeneous Liquid-Liquid Extraction (HoLLE Using a pH-Responsive Fluorine-Based Surfactant

Directory of Open Access Journals (Sweden)

Shotaro Saito

2015-08-01

Full Text Available A selective separation and recycling system for metal ions was developed by homogeneous liquid-liquid extraction (HoLLE using a fluorosurfactant. Sixty-two different elemental ions (e.g., Ag, Al, As, Au, B, Ba, Be, Bi, Ca, Cd, Ce, Co, Cr, Cu, Dy, Er, Eu, Fe, Ga, Gd, Ge, Hf, Hg, Ho, In, Ir, La, Lu, Mg, Mn, Mo, Nb, Nd, Ni, Os, P, Pb, Pd, Pr, Pt, Re, Rh, Ru, Sb, Sc, Se, Si, Sm, Sn, Sr, Ta, Tb, Te, Ti, Tl, Tm, V, W, Y, Yb, Zn, and Zr were examined. By changing pH from a neutral or alkaline solution (pH ≥ 6.5 to that of an acidic solution (pH < 4.0, gallium, zirconium, palladium, silver, platinum, and rare earth elements were extracted at >90% efficiency into a sedimented Zonyl FSA® (CF3(CF2n(CH22S(CH22COOH, n = 6–8 liquid phase. Moreover, all rare earth elements were obtained with superior extraction and stripping percentages. In the recycling of rare earth elements, the sedimented phase was maintained using a filter along with a mixed solution of THF and 1 M sodium hydroxide aqueous solution. The Zonyl FSA® was filtrated and the rare earth elements were recovered on the filter as a hydroxide. Furthermore, the filtrated Zonyl FSA was reusable by conditioning the subject pH.

Direct evidence for the first-order phase transition at the lower critical temperature in Er/sub 1-x/Ho/sub x/Rh4B4

International Nuclear Information System (INIS)

Lachal, B.; Ishikawa, M.; Junod, A.; Muller, J.

1982-01-01

Using a heat-pulse and a relaxation technique, we have performed an extensive calorimetric investigation on the reetrant superconductors Er/sub 1-x/Ho/sub x/Rh 4 B 4 (x = 0.4 and 0.6) around their lower critical temperature. These experiments revealed a supercooling effect and thermal hystersis, thus establishing the first-order nature of the transition. Based on the measurement of the latent heat, our thermodynamic analysis suggests that the onset of ferromagnetism is lowered by only 55 mK due to the competing superconducting phase. Results of magnetization and ac susceptibility experiments on these compounds are also included

MBE growth and characterisation of light rare-earth superlattices

DEFF Research Database (Denmark)

Ward, R.C.C.; Wells, M.R.; Bryn-Jacobsen, C.

1996-01-01

The molecular beam epitaxy growth techniques which have already successfully produced a range of heavy rare-earth superlattices have now been extended to produce superlattices of two light rare-earth elements, Nd/Pr, as well as superlattices and alloy films of a heavy/light system, Ho/Pr. High......-resolution X-ray diffraction analysis shows the Nd/Pr superlattices to be of high structural quality, while the Ho/Pr superlattices are significantly less so. In the Ho/Pr superlattices, Pr is found to retain its bulk dhcp crystal structure even in thin layers (down to 6 atomic planes thick) sandwiched between...... thick layers of hcp Ho. In addition, neutron diffraction studies of the He/Pr superlattices have shown that the helical Ho magnetic order is not coherent through the dhcp Pr layers, in contrast to previous hcp/hcp superlattices Ho/Y, Ho/Lu and Ho/Er. The series of Ho:Pr alloy films has shown structural...

Levels in 159Ho as populated from decay of 159Er

International Nuclear Information System (INIS)

Boutet, J.

1977-06-01

The level scheme of the odd proton nucleus 159 Ho has been investigated using Ge(Li) and Si(Li) detectors. Results of γ-ray singles, conversion electron spectra and coincidence experiments are reported. Assignments are made for several energy levels

Water-stable NaLuF4-based upconversion nanophosphors with long-term validity for multimodal lymphatic imaging.

Science.gov (United States)

Zhou, Jing; Zhu, Xingjun; Chen, Min; Sun, Yun; Li, Fuyou

2012-09-01

Multimodal imaging is rapidly becoming an important tool for biomedical applications because it can compensate for the deficiencies of individual imaging modalities. Herein, multifunctional NaLuF(4)-based upconversion nanoparticles (Lu-UCNPs) were synthesized though a facile one-step microemulsion method under ambient condition. The doping of lanthanide ions (Gd(3+), Yb(3+) and Er(3+)/Tm(3+)) endows the Lu-UCNPs with high T(1)-enhancement, bright upconversion luminescence (UCL) emissions, and excellent X-ray absorption coefficient. Moreover, the as-prepared Lu-UCNPs are stable in water for more than six months, due to the protection of sodium glutamate and diethylene triamine pentacetate acid (DTPA) coordinating ligands on the surface. Lu-UCNPs have been successfully applied to the trimodal CT/MR/UCL lymphatic imaging on the modal of small animals. It is worth noting that Lu-UCNPs could be used for imaging even after preserving for over six months. In vitro transmission electron microscope (TEM), methyl thiazolyl tetrazolium (MTT) assay and histological analysis demonstrated that Lu-UCNPs exhibited low toxicity on living systems. Therefore, Lu-UCNPs could be multimodal agents for CT/MR/UCL imaging, and the concept can be served as a platform technology for the next-generation of probes for multimodal imaging. Copyright © 2012 Elsevier Ltd. All rights reserved.

Journal of Earth System Science | Indian Academy of Sciences

Indian Academy of Sciences (India)

The rare earth elements like La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu and the heavy metals like Mg, V, Cr, Mn, Fe, Cu, Zn, U, Th were analysed by using standard analytical methods. The Post-Archean Australian Shale composition was used to normalise the rare earth elements. It was found that the sediments ...

Preparation, thermogravimetric study and infrared spectra of rare earth acetates

International Nuclear Information System (INIS)

Graehlert, X.; Starke, M.

1992-01-01

The anhydrous and the hydrated acetates of Ho, Er, Tm, Yb and Lu have been prepared. The compounds obtained have been investigated by thermogravimetric analysis and infrared spectroscopy. The thermal decomposition of the rare earth acetates may proceed via various steps. It depends on both the number of crystal water molecules in the acetates and the rare earth element's behaviour. (orig.)

Magnetic properties of RNi5-xCux intermetallics

International Nuclear Information System (INIS)

Kuchin, A.G.; Ermolenko, A.S.; Kulikov, Yu.A.; Khrabrov, V.I.; Rosenfeld, E.V.; Makarova, G.M.; Lapina, T.P.; Belozerov, Ye.V.

2006-01-01

The magnetic properties have been studied for the series of RNi 5-x Cu x intermetallics with R=Y, La, Ce, Pr, Nd, Sm, Gd, Tb, Dy, Ho, Er, Tm, Lu; x= 5-x Cu x but GdNi 5-x Cu x . These results are explained in the frame of band magnetism, random local crystal field, and domain wall pinning theories

Effects of pressure and magnetic field on transport properties of Y1-xRxCo2 alloys (R=Gd, Tb, Dy, Ho and Er)

International Nuclear Information System (INIS)

Takaesu, Y; Nakama, T; Kinjyo, A; Yonamine, S; Hedo, M; Yagasaki, K; Uchima, K; Uwatoko, Y; Burkov, A T

2010-01-01

Electrical resistivity ρ and thermopower S of Y 1-x R x Co 2 (R=Gd, Tb, Dy, Ho and Er) Laves phase alloy systems were measured at temperatures from 1.5 K to 300 K in magnetic fields up to 15 T and under hydrostatic pressure up to 2 GPa. We show that there is a universal linear relation between the pressure and magnetic field derivatives of the resistivity, dρ/dP and dρ/dB, with gradient, determined by pressure derivative of the critical metamagnetic field of the cobalt 3d electron system. A similar scaling behavior was found for the thermopower dependencies on pressure and alloy composition.

Spectral properties of hydrothermally-grown Nd:LuAG, Yb:LuAG, and Yb:Lu{sub 2}O{sub 3} laser materials

Energy Technology Data Exchange (ETDEWEB)

Brown, David C., E-mail: DBrown@snakecreeklasers.com [Snake Creek Lasers LLC, Friendsville, PA 18818 (United States); McMillen, Colin D.; Moore, Cheryl; Kolis, Joseph W. [Department of Chemistry and Center for Optical Materials Science and Engineering Technologies, Clemson University, Clemson, SC 29634-0973 (United States); Envid, Victoria [Snake Creek Lasers LLC, Friendsville, PA 18818 (United States)

2014-04-15

We have investigated the hydrothermal growth of, and spectrally characterized, the lutetium based laser materials Nd:LuAG, Yb:LuAG, and Yb:Lu{sub 2}O{sub 3}. Absorption cross-section data are presented for Nd:LuAG at 83, 175, and 295 K. Absorption cross-section data was also obtained for Yb:LuAG at 83, 175, and 295 K; the 295 K data was used to generate emission cross-sections using the method of reciprocity. For Yb:Lu{sub 2}O{sub 3}, we present absorption cross-sections at 295 K as well as emission cross-sections derived using reciprocity. -- Highlights: • We present spectral properties for hydrothermally-grown laser crystals. • Absorption cross-section data are presented for Nd:LuAG and Yb:LuAG at 83, 175, and 295 K. • Emission cross-sections are presented for Yb:LuAG at 295 K derived by reciprocity. • We present absorption cross-sections at 295 K as well as emission cross-sections derived using reciprocity for the laser material Yb:Lu{sub 2}O{sub 3}.

The ternary rare earth ruthenium gallides R3Ru4Ga15 (R=Y, Tb-Er) with a new structure type, a further example of a recently recognized large family of structures

International Nuclear Information System (INIS)

Schlueter, Martin; Jeitschko, Wolfgang

2003-01-01

The title compounds were prepared by reaction of the elemental components at high temperature. They crystallize with a new orthorhombic structure type which was determined from single-crystal diffractometer data of Ho 3 Ru 4 Ga 15 : Pnma, a=871.7(1) pm, b=956.4(1) pm, c=1765.9(3) pm, Z=4, R=0.040 for 1039 structure factors and 114 variable parameters. The structure may be viewed as consisting of two kinds of atomic layers, although atomic bonding within and between the layers is comparable strength, as can be judged from the near-neighbor environments, where all of the 15 atomic sites have high coordination numbers. One kind of atomic layers (A) contains all of the holmium and additional gallium atoms in the ratio Ho:Ga=3:5 with a unit mesh content of 2Ho 3 Ga 5 ; these layers are flat. The other layers (B) consist of sheets of corner- and edge-sharing condensed RuGa 6 octahedra, which are extremely compressed resulting in a hexagonal close-packed, puckered net with a Ru:Ga ratio of 2:5 and a unit mesh content of 4Ru 2 Ga 5 . These nets alternate in the sequence ABAB, ABAB, thus yielding the formula 4Ho 3 Ga 5 ·8Ru 2 Ga 5 =4Ho 3 Ru 4 Ga 15 . Similar layers are observed in the structures of Y 2 Co 3 Ga 9 , Gd 3 Ru 4 Al 12 , Er 4 Pt 9 Al 24 , CeOsGa 4 , CaCr 2 Al 10 , and the four stacking variants with the compositions TbRe 2 Al 10 , DyRe 2 Al 10 , YbFe 2 Al 10 , and LuRe 2 Al 10

Neutron scattering study of magnetic and crystalline electirc field interactions in RCrO3

International Nuclear Information System (INIS)

Shamir, N.

1978-05-01

Magnetic and crystalline electric field interactions in the compounds RCrO 3 (R-rare earth) , were studied by neutron scattering. Elastic neutron scattering was utilized in the study of the temperature dependence of the Cr 3+ and Ho 3+ magnetic reflections in Lu CrO 3 and HoCrO 3 , respectively. Analysis of this temperature dependence yielde constant canting angles for the Cr 3+ and Ho 3+ magnetic moments. Molecular magnetic field constants and crystalline electric field splitting were also calculated from the temperature dependence of the Ho 3+ magnetic reflection. These parameters were obtained directly by inelastic neutron scattering measurement. Inelastic neutron scattering measurements of crystlline electric field transitions of R 3+ (R=Pr, Nd, Tb, Ho, Er, Tm, Yb) in RCrO 3 , formed the basis for the calculation of the common crystalline electirc field parameters of the heavy R 3+ ions. (author)

EC/β+ decay of 161Er

International Nuclear Information System (INIS)

Kalinnikov, V.G.; Ibraheem, Y.S.; Stegailov, V.I.

2004-01-01

Full text: The study of odd-proton nuclei in rare-earth region has been performed to get more information on the nuclear structure of these nuclei. In the framework of a program at the ISOL complex of YASNAPP-2 at JINR to study the decay of odd-nuclei, 161 Er has been investigated. The experiments have been focused on the 161 Ho level scheme populated in the EC/β + decay of 161 Er for which a few results have been previously reported [1,2]. Spectra of single γ-ray, γ-γ coincidence and internal conversion electrons were measured. There are appreciable disagreements between results of some γ-ray intensities obtained by us and in [2]. The greatest difference was for relative γ-ray intensity of the 11.28 keV, which has reported value I γ ∼ 10 (I γ 211 =1000) in [2], but this leads to an overpopulation of the 211 keV level by 14% of the decay [3]. The relative intensities of transitions with Eγ γ211 =1000). Inaccuracy of Iγ in [2] is probably due to a sudden change in the efficiency curve of their Ge(Li) detector in the low energy region while our HPGe detector feature a much smoother variation in the efficiency curve in this γ-ray energy region. Besides, the levels earlier introduced by us in [4], three new levels in 161 Ho were proposed from γ-γ coincidences at energies 693.2 keV, 859.6 keV, and 957.97 keV. Spins, parities and Nilsson quantum characteristics of some 161 Ho levels were established

Radiation hardness of LuAG:Ce and LuAG:Pr scintillator crystals

CERN Document Server

Derdzyan, M V; Belsky, A; Dujardin, C; Lecoq, P; Lucchini, M; Ovanesyan, K L; Pauwels, K; Pedrini, C; Petrosyan, A G

2012-01-01

Single crystals of LuAG:Ce, LuAG:Pr and un-doped LuAG were grown by the vertical Bridgman method and studied for radiation hardness under gamma-rays with doses in the range 10-10(5) Gy (Co-60). A wide absorption band peaking at around 600 nm springs up in all three types of crystals after the irradiations. The second band peaking at around 375 nm appears in both LuAG:Pr and un-doped LuAG. Compositional variations have been done to reveal the spectral behavior of induced color centers in more detail and to understand their origin. Similarities in behavior of Yb2+ centers in as-grown garnets are found, indicating that radiation induced color centers can be associated with residual trace amounts of Yb present in the raw materials. Un-doped LuAG and LuAG:Ce demonstrate moderate radiation hardness (the induced absorption coefficients being equal to 0.05-0.08 cm(-1) for accumulated doses of 10(3)-10(4) Gy), while LuAG:Pr is less radiation hard. The ways to improve the radiation hardness are discussed.

Complexes of heavy lanthanides with o-aminobenzoic acid

International Nuclear Information System (INIS)

Brzyska, W.; Rzaczynska, Z.

1988-01-01

Anthranilates of Tb-Lu prepared in the reaction of the rare earth hydroxides with ortho-aminobenzoic acid (anthranilic acid) have the general formula Ln(C 6 H 4 NH 2 COO) 3 centredot 2H 2 O where Ln = Tb, Dy, Ho, Er, Tm, Yb, Lu. The water molecules in the hydrated compounds are in the outer coordination sphere. On heating in air at 493 K dehydration occurs and the anhydrous anthranilates Ln(C 6 H 4 NH 2 COO) 3 are formed. On the basis of the IR spectra it was found that the metal in dihydrated anthranilates was simultaneously coordinated through amino and carboxyl groups whereas in anhydrous anthranilates only through the bidentate carboxyl group. From X-ray analysis it was stated that the anthranilates Ln(C 6 H 4 NH 2 COO) 3 centredot 2H 2 O are isostructural, whereas the anhydrous compounds Ln(C 6 H 4 NH 2 COO) 3 are isostructural in the two groups Tb-Er and Tm-Lu. (Author)

Spectroscopic characterization and temporal dynamics of energy transfer process between Tm3+ -Ho3+ and Yb3+ -Tm3+ ions in LiYF4 and LiLuF4 crystals

International Nuclear Information System (INIS)

Tarelho, Luiz Vicente Gomes

2001-01-01

In this work, we perform spectroscopic studies to characterize the energy transfer processes occurring in rare-earth doped lithium fluoride systems, aiming the optimization of the population inversion of these media. Yb 3+ ion was used in order to probe the electron-phonon coupling in LiYF 4 , LiGdF 4 and LiLuF 4 matrices. In these systems it was obtained the average phononenergy, the vibronic transition probability and Huang-Rhys coupling constant. These parameters are dependent on the crystal host and the LiLuF 4 system presents excluded correlation effects, an electronic repulsion that weakens the vibronic coupling. The Tm:Ho:LiYF 4 system was studied under diode laser pumping at 796 nm, aiming the 2 μm emission optimization. The ideal conditions of concentration and laser power were determined favouring the latter emission. Upconversion processes of two photons were identified besides the energy transfer among ions. The dynamic processes of luminescence of donors and acceptors allowed one to classify the energy transfer process as an energy transfer process assisted by fast diffusion among donors. The spectroscopic study of the Yb:Tm:LiYF 4 allowed the determination of efficient non resonant transfer mechanisms between ( 2 F 5/2 ) Ytterbium level and ( 3 H 5 ) Thulium level, assisted by two phonon with hopping migration among donors ( Foerster-Burshtein model). The repopulation process of the Yb donor level is due to a cooperative sensitization between Yb-Tm pairs followed by an energy transfer process. (author)

Synthesis, thermal and magnetic properties of RE-diborides

Energy Technology Data Exchange (ETDEWEB)

Novikov, V.V., E-mail: vvnovikov@mail.ru [Training-Research Center ' Bryansk Physical Laboratory' , Petrovsky Bryansk State University, 14, Bezhitskaya St, 241036 Bryansk (Russian Federation); Matovnikov, A.V. [Training-Research Center ' Bryansk Physical Laboratory' , Petrovsky Bryansk State University, 14, Bezhitskaya St, 241036 Bryansk (Russian Federation); Volkova, O.S. [Lomonosov Moscow State University, GSP-1, Leninskie Gory, 119991 Moscow (Russian Federation); Vasil' ev, A.N., E-mail: vasil@mig.phys.msu.ru [Lomonosov Moscow State University, GSP-1, Leninskie Gory, 119991 Moscow (Russian Federation)

2017-04-15

Techniques of synthesis of RE diborides (RB{sub 2}) are developed (R=Tb, Dy, Ho, Er, Lu). Temperature dependence of magnetisation, a heat capacity, a lattice parameters of diborides in the range of 2–300 K are measured. According to joint calorimetric and X-ray research the analysis of a phonon component of a heat capacity and thermal expansion of RE-diborides is carried out by Debye-Einstein's models, the parameters of the model are determined. The change of magnetisation of the ferromagnetic RB{sub 2} compounds with growth of temperature caused by violation of ordering in the system of the atomic magnetic moments is compared with the change of entropy of a magnetic subsystem calculated from calorimetric data. Analytical expansion for calculation of a magnetic component of a heat capacity by RB{sub 2} magnetisation data at the temperatures of 2–300 K is obtained. - Highlights: • 1 Techniques of synthesis of RE diborides (RB{sub 2}) are developed (R=Tb, Dy, Ho, Er, Lu). • 2 Temperature dependence of magnetisation of diborides at 2–300 K is determined. • 3 Calculation method of RB{sub 2} magnetic heat capacity from magnetic data is obtained.

Magnetic structures of holmium-lutetium alloys and superlattices

DEFF Research Database (Denmark)

Swaddling, P.P.; Cowley, R.A.; Ward, R.C.C.

1996-01-01

Alloys and superlattices of Ho and Lu have been grown using molecular beam epitaxy and their magnetic structures determined using neutron-scattering techniques. The 4f moments in the alloys form a helix at all compositions with the moments aligned in the basal plane perpendicular to the wave vector...... of the helix remaining coherent through the nonmagnetic Lu blocks. The neutron scattering from the superlattices is consistent with a model in which there are different phase advances of the helix turn angle through the Ho and Lu blocks, but with a localized moment on the Ho sites only. A comparison...... of Ho and Lu. At low temperatures, for superlattices with fewer than approximately twenty atomic planes of Ho, the Ho moments within a block undergo a phase transition from helical to ferromagnetic order, with the coupling between successive blocks dependent on the thickness of the Lu spacer....

IUPAC-NIST Solubility Data Series. 100. Rare Earth Metal Fluorides in Water and Aqueous Systems. Part 3. Heavy Lanthanides (Gd–Lu)

Energy Technology Data Exchange (ETDEWEB)

Mioduski, Tomasz [Institute of Nuclear Chemistry and Technology, 03195 Warszawa (Poland); Gumiński, Cezary, E-mail: cegie@chem.uw.edu.pl [Department of Chemistry, University of Warsaw, 02093 Warszawa (Poland); Zeng, Dewen, E-mail: dewen-zeng@hotmail.com [College of Chemistry and Chemical Engineering, Central South University, Changsha 410083 (China)

2015-06-15

This is the third part of the volume devoted to solubility data for the rare earth metal (REM) fluorides in water and in aqueous ternary and multicomponent systems. It covers experimental results of trivalent fluorides of Gd, Tb, Dy, Ho, Er, Tm, Yb, and Lu (so-called heavy lanthanides), since no quantitative data on solubilities of TbF{sub 4} and YbF{sub 2} (the most stable compounds at these valencies) are available. The related literature has been covered through the end of 2014. Compilations of all available papers with the solubility data are introduced for each REM fluoride with a corresponding critical evaluation. Every such assessment contains a collection of all solubility results in aqueous solution, a selection of suggested solubility data, a solubility equation, and a brief discussion of the multicomponent systems. Only simple fluorides (no complexes or double salts) are treated as the input substances in this report. General features of the systems, such as nature of the equilibrium solid phases, solubility as a function of temperature, influence of ionic strength, solution pH, mixed solvent medium on the solubility, quality of the solubility results, and the solubility as a function of REM atomic number, have already been presented in Part 1 of the volume.

Chemical composition of Kiscellian silty sediment (sivica from the Trobni Dol area, Eastern Slovenia

Directory of Open Access Journals (Sweden)

Miha Mišič

2003-06-01

Full Text Available Kiscellian marine silt termed »sivica« is widely developed in Tertiary basins of Eastern Slovenia. Chemical composition is rather uniform and reflects the dominance of filosilicates (mainly illite/muscovite, chlorite and montmorillonite and carbonates. PAAS normalised REE and Y abundances are slightly depleted for La, Ce, Pr and Nd, very close to PAAS for Sm, Eu, Gd and Tb, and depleted for Y, Ho, Er, Tm, Yb and Lu.

Emission bands of phosphorus and calculation of band structure of rare earth phosphides

International Nuclear Information System (INIS)

Al'perovich, G.I.; Gusatinskij, A.N.; Geguzin, I.I.; Blokhin, M.A.; Torbov, V.I.; Chukalin, V.I.; AN SSSR, Moscow. Inst. Novykh Khimicheskikh Problem)

1977-01-01

The method of x-ray emission spectroscopy has been used to investigate the electronic structure of monophosphides of rare-earth metals (REM). The fluorescence K bands of phosphorus have been obtained in LaP, PrP, SmP, GdP, TbP, DyP, HoP, ErP, TmP, YbP, and LuP and also the Lsub(2,3) bands of phosphorus in ErP, TmP, YbP, and LuP. Using the Green function technique involving the muffin-tin potential, the energy spectrum for ErP has been calculated in the single-electron approximation. The hystogram of electronic state distribution N(E) is compared with the experimental K and Lsub(2,3) bands of phosphorus in ErP. The agreement between the main details of N(E) and that of x-ray spectra allows to state that the model used provides a good description of the electron density distribution in crystals of REM monophosphides. In accordance with the character of the N(E) distribution the compounds under study are classified as semimetals or semiconductors with a very narrow forbidden band

Mechanism of estrogen-mediated attenuation of hepatic injury following trauma-hemorrhage: Akt-dependent HO-1 up-regulation.

Science.gov (United States)

Hsu, Jun-Te; Kan, Wen-Hong; Hsieh, Chi-Hsun; Choudhry, Mashkoor A; Schwacha, Martin G; Bland, Kirby I; Chaudry, Irshad H

2007-10-01

Protein kinase B (Akt) is known to be involved in proinflammatory and chemotactic events in response to injury. Akt activation also leads to the induction of heme oxygenase (HO)-1. Up-regulation of HO-1 mediates potent, anti-inflammatory effects and attenuates organ injury. Although studies have shown that 17beta-estradiol (E2) prevents organ damage following trauma-hemorrhage, it remains unknown whether Akt/HO-1 plays any role in E2-mediated attenuation of hepatic injury following trauma-hemorrhage. To study this, male rats underwent trauma-hemorrhage (mean blood pressure, approximately 40 mmHg for 90 min), followed by fluid resuscitation. At the onset of resuscitation, rats were treated with vehicle, E2 (1 mg/kg body weight), E2 plus the PI-3K inhibitor (Wortmannin), or the estrogen receptor (ER) antagonist (ICI 182,780). At 2 h after sham operation or trauma-hemorrhage, plasma alpha-GST and hepatic tissue myeloperoxidase (MPO) activity, IL-6, TNF-alpha, ICAM-1, cytokine-induced neutrophil chemoattractant-1, and MIP-2 levels were measured. Hepatic Akt and HO-1 protein levels were also determined. Trauma-hemorrhage increased hepatic injury markers (alpha-GST and MPO activity), cytokines, ICAM-1, and chemokine levels. These parameters were markedly improved in the E2-treated rats following trauma-hemorrhage. E2 treatment also increased hepatic Akt activation and HO-1 expression compared with vehicle-treated, trauma-hemorrhage rats, which were abolished by coadministration of Wortmannin or ICI 182,780. These results suggest that the salutary effects of E2 on hepatic injury following trauma-hemorrhage are in part mediated via an ER-related, Akt-dependent up-regulation of HO-1.

Cross sections of (n, α) reactions on rare-earth elements from Tb through Lu at En ∼ 14 MeV

International Nuclear Information System (INIS)

Kadenko, A.O.; Gorbachenko, O.M.; Primenko, G.I.; Kadenko, I.M.; Plujko, V.A.

2012-01-01

The cross sections of the neutron reactions at E n = 14.6 MeV on the isotopes of Tb-159, Dy-164, Er-168, Er-170, Yb-174, Yb-176, Lu-175, and Lu-176 with alpha-particle emission were studied by the use of new experimental data and different theoretical approaches. New and improved experimental data were obtained with the neutron-activation technique. The samples of natural composition of rare earth elements were irradiated with d-t neutrons from the neutron generator NG-300. Gamma-ray spectra of the induced activities of irradiated samples were measured with HPGe spectrometer. The uncertainties of the experimental cross sections were thoroughly estimated. Available experimental results and evaluated nuclear data from the EXFOR, TENDL, ENDF data libraries were compared with different systematics and calculations with the EMPIRE 3.0 and TALYS 1.2 codes. Contribution of pre-equilibrium decay was analyzed. Different systematics for estimations of the investigated cross-sections have been tested

Evidence for a magnetic moment at the Lu site of LuFe2

International Nuclear Information System (INIS)

Kasamatsu, Y.; Armitage, J.G.M.; Lord, J.S.; Riedi, P.C.; Fort, D.

1995-01-01

High pressure 175 Lu NMR measurements of LuFe 2 at 4.2 K suggest that Lu, like Y and Zr, carries a negative magnetic moment, in agreement with self-consistent energy band calculations. The observed spectrum is more complicated than would be expected for a Laves phase compound. ((orig.))

n-aminobenzoates of rare earths

International Nuclear Information System (INIS)

Efremova, G.I.; Buchkova, R.T.; Lapitskaya, A.V.; Pirkes, S.B.

1977-01-01

N-aminobenzoates of r.e.e. have been synthesized. Their composition corresponds to the general formula Me(C 6 H 4 NH 2 COO) 3 xnH 2 O, where Me stands for La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu; n=1.2. The compounds obtained are identified by chemical analysis and roentgenographically. Their solubility products, which are values of the order of 10 -9 -10 -10 , are determined

Phase relations in Ca(Sr)MoO4-Ln2(NoO4)3 systems (Ln = Pr-Lu)

International Nuclear Information System (INIS)

Vakalyuk, V.V.; Evdokimov, A.A.; Berezina, T.A.

1982-01-01

Using the methods of X-ray phase and differential thermal analyses phase ratios in the systems Ca(Sr)MoO 4 -Ln 2 (MoO 4 ) 3 at Ln=Pr-Lu are studied and phase diagrams of the systems CaMoO 4 -Ln 2 (MoO 4 ) 3 , for Ln=Nd, Gd, Yb and SrMoO 4 -Sm 2 (MoO 4 ) 3 are built. It is shown that phase ratios in the systems are similar for the following groups of rare earths: Pr-Sm, Eu-Tb, Ho-Lu. In the first group of systems ordered phase over all subsolidus region are formed, in the second one - ordered phases with scheelite-like structure and wide regions of homogeneity on the basis of Ca(Sr)MoO 4 are formed above the temperature of polymorphous transformation of rare earth molybdates, for the third group of systems intermediate compounds are not detected

Studies on the electrochemical behavior of heavy lanthanide ions and the synthesis, characterization of heavy metal chelate complexes

International Nuclear Information System (INIS)

Kang, Sam Woo; Chang, Choo Hwan; Son, Byung Chan; Suh, Moo Yul; Kim, Chae Kyun

1991-01-01

Electrochemical behavior of some heavy lanthanide ions(Gd 3+ , Tb 3+ , Dy 3+ , Ho 3+ , Er 3+ , Tm 3+ , Yb 3+ and Lu 3+ ) in various supporting electrolytes has been investigated by dc polarography, differential pulse polarography and cyclic voltammetry. The peak potentials and the peak currents, their dependency on the concentration and pH effects, the reversibility of the electrode reactions are described. The reduction of Gd 3+ , Tb 3+ , Dy 3+ , Ho 3+ , Er 3+ , Tm 3+ and Lu 3+ ions in 0.1M lithium chloride solution proceeds by a three-electron change directly to the metallic state, whereas the reduction of Yb 3+ proceeds by a one-electron change followed by a two-electron change. It was found that, in differential pulse polarography and cyclic voltammetry, the peak potential, peak current and current function showed constant value in the pH range of 4.0-6.0 by varying pH and scan rates. And also the current function is found to decrease as the sweep rate is increased when the pH reaches 4.0. This fact may indicate a chemical reaction coupled with the electrochemical reaction at lower pH values(pH 3+ ion is possible to determine voltammetrically within the error of ±3.5% in the presence of other competitive lanthanide ions. (Author)

Investigations of the trend followed in heat capacity of Re_6UO_1_2 (s) along lanthanide series

International Nuclear Information System (INIS)

Sahu, Manjulata; Saxena, M.K.; Rawat, Deepak; Dash, Smruti

2017-01-01

The compound RE_6UO_1_2 (s) (RE = Ho, Er, Tm, Yb and Lu) was synthesized by complex polymerisation method and characterised using X-ray diffraction (XRD). Heat capacity measurements of RE_6UO_1_2 (s) were performed with heat flux-type differential scanning calorimeter in the temperature range of 300-870 K. The trend in heat capacity along the rare earth series was proposed for RE_6UO_1_2 (s) and thermodynamic functions were generated. (author)

Synthesis and investigation of rare earth tris-acetylacetonates addUcts with acetylaceoneimine

International Nuclear Information System (INIS)

Trembovetskij, G.V.; Smirnov, E.V.; Murav'eva, I.A.; Martynenko, L.I.

1983-01-01

Adducts of tris-acetylacetonates of pare earths With acetylacetonimine of the composition MA 3 x2L (M=La, Pr, Nd, Eu, Gd, Tb) and MA 3 XL (M=Dy, Ho, Er, Tm, Yb, LU) have been synthesized. The compounds prepared are studied using the methods of elemental analysis, IR spectroscopy, PMR spectroscopy, X-ray phase analysis. Volatile tris-acetylacetonates of the yttrium subgroUp rare earths have been prepared by thermal decomposition of MA 3 xL in vacuum

Synthesis, properties, structure and thermochemistry of hexa-aqua-tris (N,N-dimethylformamide) lanthanide tri fluoro methane sulfonates

International Nuclear Information System (INIS)

Araujo Melo, D.M. de.

1989-01-01

Addition compounds between several lanthanide salts and dimethylformamide (DMF) have been described in the literature. This thesis reports the synthesis and characterization of the compounds of general composition Ln (C H 3 SO 3 ) 3 . 3 DMF.6 H 3 O) (Ln = La - Ho) and Ln (C H 3 SO 3 ) 3 DMF.6 H 2 O (Ln = Er - Lu). The structure of the neodymium compound, isomorphous with the series, is also described. The enthalpy variations were determined by solution calorimetry. (author)

Beam delivery system for Ho:YLF and applications in endodontics; Sistema de entrega de feixe para laser de Ho:YLF e aplicacoes em endodontia

Energy Technology Data Exchange (ETDEWEB)

Bachmann, Luciano

2000-07-01

The beam delivery systems, whether using fibers or articulated arms, are very important for the expansion of laser applications into life sciences. This work aims to couple an optical fiber to a home-made Er:Tm:Ho:LiYF{sub 4} laser. For this purpose the beam profile was studied using the beam quality factor M{sup 2} to achieve an homogeneous beam. To determine the M{sup 2} factor, the knife-edge technique was used, relating the laser energy eclipsed by the knife with its transversal position. The resonant cavity was made suitable in order to obtain a stable and homogeneous transversal beam profile, for the optical fiber coupling. It was used a 365 {mu}m diameter core low OH{sup -} content fused silica optical fiber, with a proximal SMA-905 connection and a flat distal end. M{sup 2} factors for the Ho:YLF were between 3 and 8, with a non astigmatic beam, although it was observed a divergence asymmetry in the transversal sections. The coupling efficiency was 96%, and in a repeated operation without any adjustment, the new coupling were 82% and 81%. Lasers have being recently used as an adjunct to conventional endodontic preparation to reduce intracanal microbial, preventing reinfection. The knowledge of thermal profile in endodontic procedures is important to determine laser irradiation conditions avoiding periodontal damages. In this sense, the second scope of this work was to use the Ho:YLF system to register the thermal profile in vitro and to compare the results with those obtained with Nd:YAG and Er:YAG commercial lasers. The temperature was recorded in real time through a thermocouple probe at the root apex , resulting in maximum increase of 7 deg C. (author)

Návrh raketového motoru

OpenAIRE

Cejpek, Jakub

2009-01-01

Cílem této práce je navrhnout raketový motor na tuhou pohonnou hmotu s dostatečným výkonem pro vynesení zátěže o hmotnosti 500 gramů do výšky 1500 metrů. A dále navrhnout základní uspořádání rakety, která by tento motor využila. Návrh motoru se řeší nejprve teoreticky. Tedy bez ohledu na dostupnost konstrukčního materiálu, paliva a výrobních technologií. Po vyřešení této teoretické části je na se v řešení zohlední dostupnost výše zmíněných prostředků. To znamená nejprve určit vhodné a dostupn...

Estimation of human absorbed dose for (166)Ho-PAM: comparison with (166)Ho-DOTMP and (166)Ho-TTHMP.

Science.gov (United States)

Vaez-Tehrani, Mahdokht; Zolghadri, Samaneh; Yousefnia, Hassan; Afarideh, Hossein

2016-10-01

In this study, the human absorbed dose of holmium-166 ((166)Ho)-pamidronate (PAM) as a potential agent for the management of multiple myeloma was estimated. (166)Ho-PAM complex was prepared at optimized conditions and injected into the rats. The equivalent and effective absorbed doses to human organs after injection of the complex were estimated by radiation-absorbed dose assessment resource and methods proposed by Sparks et al based on rat data. The red marrow to other organ absorbed dose ratios were compared with these data for (166)Ho-DOTMP, as the only clinically used (166)Ho bone marrow ablative agent, and (166)Ho-TTHMP. The highest absorbed dose amounts are observed in the bone surface and bone marrow with 1.11 and 0.903 mGy MBq(-1), respectively. Most other organs would receive approximately insignificant absorbed dose. While (166)Ho-PAM demonstrated a higher red marrow to total body absorbed dose ratio than (166)Ho-1,4,7,10-tetraazacyclo dodecane-1,4,7,10 tetra ethylene phosphonic acid (DOTMP) and (166)Ho-triethylene tetramine hexa (methylene phosphonic acid) (TTHMP), the red marrow to most organ absorbed dose ratios for (166)Ho-TTHMP and (166)Ho-PAM are much higher than the ratios for (166)Ho-DOTMP. The result showed that (166)Ho-PAM has significant characteristics than (166)Ho-DOTMP and therefore, this complex can be considered as a good agent for bone marrow ablative therapy. In this work, two separate points have been investigated: (1) human absorbed dose of (166)Ho-PAM, as a potential bone marrow ablative agent, has been estimated; and (2) the complex has been compared with (166)Ho-DOTMP, as the only clinically used bone marrow ablative radiopharmaceutical, showing significant characteristics.

Resistance-Based Ceramic Ho123 Ionic Conductor for Oxygen Gas Sensing

Science.gov (United States)

Idrus, L. H.; Yahya, A. K.

2009-07-01

Oxygen sensing properties of HoBa2Cu3O7-δ ceramic rods utilizing hot-spot phenomenon have been characterized. The rods were prepared from high purity oxides using the conventional solid-state reaction method. I-V characterization showed increase in output current with voltage before the appearance of the hot spot. After the appearance of the hot-spot, the output current strongly depended on oxygen partial pressure. The rod showed stable sensing characteristics with good electrical stability and reproducibility with higher sensitivity at low oxygen partial pressure. The sensing property is associated with the absorption of oxygen and dissociation into holes and oxide ions. Ho123 is more sensitive at pO2 below 20% compared to Er123 possibly due to differences in oxygen activation energy related to RE ionic radius.

Resistance-Based Ceramic Ho123 Ionic Conductor for Oxygen Gas Sensing

International Nuclear Information System (INIS)

Idrus, L. H.; Yahya, A. K.

2009-01-01

Oxygen sensing properties of HoBa 2 Cu 3 O 7-δ ceramic rods utilizing hot-spot phenomenon have been characterized. The rods were prepared from high purity oxides using the conventional solid-state reaction method. I-V characterization showed increase in output current with voltage before the appearance of the hot spot. After the appearance of the hot-spot, the output current strongly depended on oxygen partial pressure. The rod showed stable sensing characteristics with good electrical stability and reproducibility with higher sensitivity at low oxygen partial pressure. The sensing property is associated with the absorption of oxygen and dissociation into holes and oxide ions. Ho123 is more sensitive at pO 2 below 20% compared to Er123 possibly due to differences in oxygen activation energy related to RE ionic radius.

CW laser properties of Nd:GdYAG, Nd:LuYAG, and Nd:GdLuAG mixed crystals

Science.gov (United States)

Di, J. Q.; Xu, X. D.; Li, D. Z.; Zhou, D. H.; Wu, F.; Zhao, Z. W.; Xu, J.; Tang, D. Y.

2011-10-01

Three mixed crystals, Nd:GdYAG, Nd:LuYAG, and Nd:GdLuAG, were grown by Czochralski method. We report the continuous-wave (CW) Nd:GdYAG, Nd:LuYAG, and Nd:GdLuAG laser operation under laser diode pumping. The maximum output powers are 4.11, 5.31, and 7.47 W, with slope efficiency of 73.0, 55.3, and 57.1%, respectively. With replacing Lu3+ or Y3+ ions with large Gd3+ ions, the pump efficiency increases.

Beam delivery system for Ho:YLF and applications in endodontics

International Nuclear Information System (INIS)

Bachmann, Luciano

2000-01-01

The beam delivery systems, whether using fibers or articulated arms, are very important for the expansion of laser applications into life sciences. This work aims to couple an optical fiber to a home-made Er:Tm:Ho:LiYF 4 laser. For this purpose the beam profile was studied using the beam quality factor M 2 to achieve an homogeneous beam. To determine the M 2 factor, the knife-edge technique was used, relating the laser energy eclipsed by the knife with its transversal position. The resonant cavity was made suitable in order to obtain a stable and homogeneous transversal beam profile, for the optical fiber coupling. It was used a 365 μm diameter core low OH - content fused silica optical fiber, with a proximal SMA-905 connection and a flat distal end. M 2 factors for the Ho:YLF were between 3 and 8, with a non astigmatic beam, although it was observed a divergence asymmetry in the transversal sections. The coupling efficiency was 96%, and in a repeated operation without any adjustment, the new coupling were 82% and 81%. Lasers have being recently used as an adjunct to conventional endodontic preparation to reduce intracanal microbial, preventing reinfection. The knowledge of thermal profile in endodontic procedures is important to determine laser irradiation conditions avoiding periodontal damages. In this sense, the second scope of this work was to use the Ho:YLF system to register the thermal profile in vitro and to compare the results with those obtained with Nd:YAG and Er:YAG commercial lasers. The temperature was recorded in real time through a thermocouple probe at the root apex , resulting in maximum increase of 7 deg C. (author)

Low-energy structure studies of odd-odd deformed nuclei and the coriolis and residual interactions

Energy Technology Data Exchange (ETDEWEB)

Dewberry, R.A.

1980-08-01

The nuclear level structure of /sup 176/Lu, /sup 170/Tm, /sup 166/Ho, and /sup 160/Tb have been studied by means of the /sup 177/Hf(t,..cap alpha..)/sup 176/Lu, /sup 171/Yb(t,..cap alpha..)/sup 170/Tm, /sup 167/Er(t,..cap alpha..)/sup 166/Ho, and /sup 161/Dy(t,..cap alpha..)/sup 160/Tb reactions and with the use of previously published (d,p) spectroscopy and gamma transitions from the (n,..gamma..) reactions. The (t,..cap alpha..) reactions have been performed and analyzed with 17 MeV tritons and the Los Alamos Q3D spectrometer. Eighty-one new rotational states in excited proton configurations or vibrational excited states are proposed. An independent parameterization of the Coriolis interaction is presented, which leads to satisfactory results in reproducing experimental single-particle transfer reaction cross-sections by theoretical calculations. The anomalous population of the excited neutron configurations (404 reduces to -624 up arrow) in /sup 176/Lu and (411 reduces to +- 512 up arrow) in /sup 170/Tm, and the anomalously low (t,..cap alpha..) cross-sections of the (411 up arrow +- 633 up arrow) configuration in /sup 166/Ho are observed. Qualitative explanation of the anomalies is presented in terms of the mixing of states which satisfy the requirement delta/sub I'/,/sub I/delta/sub K'/,/sub K/. Off-diagonal H/sub INT/ matrix elements are calculated, which show that the residual interaction cannot be used to account for the magnitude of the cross-sections observed.

Study of the production of 177Lu through 176Yb (n, γ) 177Yb → 177Lu nuclear reaction

International Nuclear Information System (INIS)

Silva, Giovana Pasqualini da; Osso Junior, Joao Alberto

2007-01-01

The beta minus emitter 177 Lu is a promising therapeutic radioisotope for the curative treatment of cancer using labelled proteins. It has a half - life of T 1/2 = 6.71 day and maximum and average β - energies of 421 and 133 keV, resulting in a short range of radiation in tissue. The decay is accompanied by the emission of low energy γ-radiation with 208.3 keV (11%) and 113 keV (6.4%) suitable for simultaneous imaging, 177 Lu can be produced by two different routes, namely, by irradiation of natural Lu 2 O 3 target ( 176 Lu, 2.6%) or enriched (in 176 Lu) Lu 2 O 3 target, as also by irradiation of Yb target (Yb 2 O 3 ) followed by radiochemical separation of 177 Lu from Yb isotopes. The objective of this work is to study the production of 177 Lu through the indirect 176 Yb(n,γ) 177 Yb → 177 Lu nuclear reaction. The results of the production yield of 177 Lu will be shown and compared with the direct reaction. The method of choice for the chemical separation between Lu and Yb was the ion exchange, using an cation exchange resin in Cl - form and α-HIBA as eluent. Preliminary results showed a good separation of 177 Lu from Yb 2 O 3 indirect targets. (author)

Memories of Lu Jingqing

Institute of Scientific and Technical Information of China (English)

1994-01-01

Lu Jingqing was a woman of letters who wrote poems when she was young and also worked as an editor and teacher. Her main works are Women poets of the Tang Dynasty (1931), Whisper (a collection of poems, 1932), Plain Writing (a collection of verses, 1930) and The Wandering (1933). In March 1993, 86-year-old Lu Jingqing, Professor of the Shanghai College of Finance and Economics, died in Shanghai. Zhu Bokang, an old friend of Lu and her husband wrote the following article in her memory.

Konstrukce nosného rámu pro satelitní anténu

OpenAIRE

Hrdonka, Štěpán

2016-01-01

Cílem bakalářské práce je konstrukční návrh nosného rámu pro satelitní anténu. Nosný rám umožní montáž satelitu na osobní automobil. Součástí řešení je i návrh rotačního uložení, které umožní rotaci paraboly kolem vertikální osy. Konstrukční řešení rámu je navrhnuto tak, aby bylo schopné odolávat požadovanému zatížení větru a jeho průhyb zásadně neovlivňoval kvalitu signálu. Pevnostní analýza byla provedena pomocí metody konečných prvků. Výsledný maximální průhyb vyšel 1,6 mm při působení vel...

Spectroscopic characterization and temporal dynamics of energy transfer process between Tm{sup 3+} -Ho{sup 3+} and Yb{sup 3+} -Tm{sup 3+} ions in LiYF{sub 4} and LiLuF{sub 4} crystals; Caracterizacao espectroscopica e dinamica temporal dos processos de transferencia de energia entre os ions Tm{sup 3+} -Ho{sup 3+} e Yb{sup 3+} -Tm{sup 3+} em cristais de LiYF{sub 4} and LiLuF{sub 4}

Energy Technology Data Exchange (ETDEWEB)

Tarelho, Luiz Vicente Gomes

2001-07-01

In this work, we perform spectroscopic studies to characterize the energy transfer processes occurring in rare-earth doped lithium fluoride systems, aiming the optimization of the population inversion of these media. Yb{sup 3+} ion was used in order to probe the electron-phonon coupling in LiYF{sub 4}, LiGdF{sub 4} and LiLuF{sub 4} matrices. In these systems it was obtained the average phononenergy, the vibronic transition probability and Huang-Rhys coupling constant. These parameters are dependent on the crystal host and the LiLuF{sub 4} system presents excluded correlation effects, an electronic repulsion that weakens the vibronic coupling. The Tm:Ho:LiYF{sub 4} system was studied under diode laser pumping at 796 nm, aiming the 2 {mu}m emission optimization. The ideal conditions of concentration and laser power were determined favouring the latter emission. Upconversion processes of two photons were identified besides the energy transfer among ions. The dynamic processes of luminescence of donors and acceptors allowed one to classify the energy transfer process as an energy transfer process assisted by fast diffusion among donors. The spectroscopic study of the Yb:Tm:LiYF{sub 4} allowed the determination of efficient non resonant transfer mechanisms between ({sup 2}F{sub 5/2}) Ytterbium level and ({sup 3}H{sub 5}) Thulium level, assisted by two phonon with hopping migration among donors ( Foerster-Burshtein model). The repopulation process of the Yb donor level is due to a cooperative sensitization between Yb-Tm pairs followed by an energy transfer process. (author)

Infrared to near-infrared and visible upconversion mechanisms in LiYF 4: Yb3+, Ho3+

NARCIS (Netherlands)

Martín-Rodríguez, R.; Meijerink, A.|info:eu-repo/dai/nl/075044986

2014-01-01

Upconversion materials have regained interest in recent years due to their potential to enhance the efficiency of solar cells. The research has focused on lanthanide based upconverters, especially Er3+- and Yb 3+-doped materials. In this paper we report Ho3+ and Yb3+ upconversion after excitation

DTA AND MOSSBAUER STUDIES IN RARE EARTH ORTHOFERRITES

Energy Technology Data Exchange (ETDEWEB)

Eibschuetz, M.; Gorodetsky, G.; Shtrikman, S.; Treves, D.

1963-11-15

Curie temperatures of 14 different orthoferrites with the chemical formula RFeO/sub 3/ (R = Y, La, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu) were measured by differential thermal analysis. Hyperfine interactions of the Fe/ sup 57/ nucleus in the same materials were determined from their Mossbauer spectra. It is found that the quadrupole splitting with the exception of the case of Sm, isomer shift, Curie temperature, and internal field vary regularly with the ionic size of R. (auth)

Constants of hyperfine interaction of lanthanoid-phosphorus for [LnCl2Hmpa4]BPh4 composition compounds from data on 1H and 31P NMR

International Nuclear Information System (INIS)

Skopenko, V.V.; Amirkhanov, V.M.; Turov, A.V.; Trachevskij, V.V.

1991-01-01

By the method of 1 H and 31 P NMR at 233 and 298 K acetone solutions of lanthanide complexes of the composition [LnCl 2 Hmpa 4 ]BPh 4 (Hmpa=OP[N(CH 3 ) 2 ] 3 , Ln=La, Ce-Lu) have been considered. Two series of complexes having similar structure of coordination sphere (Ln=Pr-Ho and Ln=Er-Yb) are revealed and for each series the values of hyperfine interaction constants, which are 0.49 and 0.28 MHz respectively, have been determined

Time-dependent transcriptional response of GOT1 human small intestine neuroendocrine tumor after 177Lu[Lu]-octreotate therapy.

Science.gov (United States)

Spetz, Johan; Rudqvist, Nils; Langen, Britta; Parris, Toshima Z; Dalmo, Johanna; Schüler, Emil; Wängberg, Bo; Nilsson, Ola; Helou, Khalil; Forssell-Aronsson, Eva

2018-05-01

Patients with neuroendocrine tumors expressing somatostatin receptors are often treated with 177 Lu[Lu]-octreotate. Despite being highly effective in animal models, 177 Lu[Lu]-octreotate-based therapies in the clinical setting can be optimized further. The aims of the study were to identify and elucidate possible optimization venues for 177 Lu[Lu]-octreotate tumor therapy by characterizing transcriptional responses in the GOT1 small intestine neuroendocrine tumor model in nude mice. GOT1-bearing female BALB/c nude mice were intravenously injected with 15 MBq 177 Lu[Lu]-octreotate (non-curative amount) or mock-treated with saline solution. Animals were killed 1, 3, 7 or 41 d after injection. Total RNA was extracted from the tumor samples and profiled using Illumina microarray expression analysis. Differentially expressed genes were identified (treated vs. control) and pathway analysis was performed. Distribution of differentially expressed transcripts indicated a time-dependent treatment response in GOT1 tumors after 177 Lu[Lu]-octreotate administration. Regulation of CDKN1A, BCAT1 and PAM at 1 d after injection was compatible with growth arrest as the initial response to treatment. Upregulation of APOE and BAX at 3 d, and ADORA2A, BNIP3, BNIP3L and HSPB1 at 41 d after injection suggests first activation and then inhibition of the intrinsic apoptotic pathway during tumor regression and regrowth, respectively. Transcriptional analysis showed radiation-induced apoptosis as an early response after 177 Lu[Lu]-octreotate administration, followed by pro-survival transcriptional changes in the tumor during the regrowth phase. Time-dependent changes in cell cycle and apoptosis-related processes suggest different time points after radionuclide therapy when tumor cells may be more susceptible to additional treatment, highlighting the importance of timing when administering multiple therapeutic agents. Copyright © 2018 The Authors. Published by Elsevier Inc. All

Luminescent properties of LuPO4-Pr and LuPO4-Eu nanoparticles

International Nuclear Information System (INIS)

Vistovskyy, V.; Malyi, T.; Vas’kiv, A.; Chylii, M.; Mitina, N.; Zaichenko, A.; Gektin, A.; Voloshinovskii, A.

2016-01-01

Spectral-luminescence parameters of LuPO 4 -Eu and LuPO 4 -Pr nanoparticles of different sizes are studied upon excitation by the synchrotron radiation with photon energies 4–40 eV. Influence of the nanoparticle size on Eu 3+ and Pr 3+ impurity luminescence is analyzed for intracenter and recombination excitation. It is shown that the luminescence intensity of impurities in the case of recombination excitation significantly stronger decreases with decreasing of nanoparticle size compared to intracenter excitation. This feature is explained by the influence of thermalization length to nanoparticle size ratio on the recombination luminescence. Electron recombination luminescence inherent for LuPO 4 -Eu nanoparticles shows a weaker dependence on the nanoparticle size than the hole one in LuPO 4 -Pr nanoparticles. The difference between energy states of praseodymium impurity ions in nanoparticles of different sizes is revealed.

Phase relations in the pseudobinary systems RAO3-R2Ti2O7 (R: rare earth element and Y, A: Fe, Ga, Al, Cr and Mn) and syntheses of new compounds R(A1-xTix)O3+x/2 (2/3≤x≤3/4) at elevated temperatures in air

Science.gov (United States)

Brown, Francisco; Jacobo-Herrera, Ivan; Alvarez-Montaño, Victor; Kimizuka, Noboru; Kurashina, Keiji; Michiue, Yuichi; Matsuo, Yoji; Mori, Shigeo; Ikeda, Naoshi; Medrano, Felipe

2017-07-01

Phase relations in the pseudo-binary systems RFeO3-R2Ti2O7 (R: Lu, Ho and Dy), RGaO3-R2Ti2O7 (R: Lu and Er), LuAlO3-Lu2Ti2O7 and RAO3-R2Ti2O7 (R: Lu and Yb. A: Cr and Mn) at elevated temperatures in air were determined by means of a classic quenching method. There exist Lu(Fe1-xTix)O3+x/2, R(Ga1-xTix)O3+x/2 (R: Lu and Er) and Lu(Al1-xTix)O3+x/2 (2/3≤ x≤3/4) having the Yb(Fe1-xTix)O3+x/2-type of crystal structure (x=0.72, space group: R3m, a(Å)=17.9773 and c(Å)=16.978 as a hexagonal setting) in these pseudo binary systems. Eighteen compounds R(A1-xTix)O3+x/2 (R: Lu-Sm and Y, A: Fe, Ga and Al) were newly synthesized and their lattice constants as a hexagonal setting were measured by means of the X-ray powder diffraction method. The R occupies the octahedral site and both A and Ti does the trigonalbipyramidal one in these compounds. Relation between lattice constants for the rhombic R(A1-xTix)O3+x/2 and the monoclinic In(A1-xTix)O3+x/2 are as follows, ah≈5 x bm, ch≈3 x cm x sin β and am=31/2 x bm, where ah and ch are the lattice constants as a hexagonal setting for R(A1-xTix)O3+x/2 and am, bm, cm and β are those of the monoclinic In(A1-xTix)O3+x/2. Crystal structural relationships among α-InGaO3 (hexagonal, high pressure form, space group: P63/mmc), InGaO3 (rhombic, hypothetical), (RAO3)n(BO)m and RAO3(ZnO)m (R: Lu-Ho, Y and In, A: Fe, Ga, and Al, B: divalent cation element, m, n: natural number), the orthorhombic-and monoclinic In(A1-xTix)O3+x/2 (A: Fe, Ga, Al, Cr and Mn) and the hexagonal-and rhombic R(A1-xTix)O3+x/2 (R: Lu-Sm and Y, A: Fe, Ga and Al) are schematically presented. We concluded that the crystal structures of both the α-InGaO3 (high pressure form, hexagonal, space group: P63/mmc) and the hypothetical InGaO3 (rhombic) are the key structures for constructing the crystal structures of these compounds having the cations with CN=5.

Complete and incomplete fusion dynamics in 20Ne + 165Ho system

International Nuclear Information System (INIS)

Linda, Sneha Bharti; Giri, Pankaj K.; Singh, D.; Kumar, Harish; Afzal Ansari, M.; Ali, Rahbar; Rashid, M.H.; Guin, R.; Das, S.K.

2016-01-01

In the present work, an attempt has been made to address some of the important aspects of CF and ICF dynamics for the system 20 Ne + 165 Ho in the projectile energy range 4-8 MeV/nucleon by employing the recoil catcher technique followed by off-line γ-ray spectroscopy. The excitation functions (EFs) of the two ERs 171 Ta and 168 Hf have been measured. In the present measurement no precursor decay contributions has been measured

Magnetic excitations in Ho2Co17 and Ho2Fe17

International Nuclear Information System (INIS)

Clausen, K.N.

1981-01-01

The low energy part ( 2 Co 17 and Ho 2 Fe 17 have been measured along the three high symmetry directions at a temperature of 4.2 K, using the inelastic neutron scattering technique. The resulting magnon dispersion relations have been interpreted using linear spin wave theory with a Hamiltonian including single ion crystal field anisotropy and isotropic exchange between spatially well localized spins. The R 2 T 17 structure contains two different Ho sites, with the same point symmetry, and from the spin wave results it was concluded that the crystal field anisotropy of the two Ho sites in both Ho 2 Co 17 and Ho 2 Fe 17 were identical. The deduced crystal field parameters for Ho 2 Fe 17 were slightly larger than for Ho 2 Co 17 , and the parameters were of the same order of magnitude as for pure Ho. For Ho 2 Fe 17 the Fe-Fe exchange was found to be anisotropic, and for both compounds the magnetic ordering temperatures of 1178 K for Ho 2 Co 17 and 335 K for Ho 2 Fe 17 were determined by the strong positive 3d-3d exchange. (Auth.)

Lanthanide phosphonates: Synthesis, thermal stability and magnetic characterization

Energy Technology Data Exchange (ETDEWEB)

Amghouz, Z., E-mail: amghouz.uo@uniovi.es [Departamentos de Quimica Fisica y Analitica y Quimica Organica e Inorganica, Universidad de Oviedo - CINN, 33006 Oviedo (Spain); Garcia, J.R.; Garcia-Granda, S. [Departamentos de Quimica Fisica y Analitica y Quimica Organica e Inorganica, Universidad de Oviedo - CINN, 33006 Oviedo (Spain); Clearfield, A. [Department of Chemistry, Texas A and M University, College Station, TX 77842-3012 (United States); Rodriguez Fernandez, J.; Pedro, I. de [CITIMAC, Facultad de Ciencias, Universidad de Cantabria, 39005 Santander (Spain); Blanco, J.A. [Departamento de Fisica, Universidad de Oviedo, 33007 Oviedo (Spain)

2012-09-25

Highlights: Black-Right-Pointing-Pointer Report of the complete series of lanthanide 1,4-phenylbis(phosphonate). Black-Right-Pointing-Pointer Synthesis under conventional hydrothermal synthesis or microwave-assisted hydrothermal synthesis. Black-Right-Pointing-Pointer Cation size is the key factor for the structural and particles size variations. Black-Right-Pointing-Pointer Thermal behaviour is characterized by unusual very high thermal stability. - Abstract: Series of novel organic-inorganic hybrids materials based on trivalent lanthanides (Ln = Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu) and 1,4-phenylbis(phosphonate) obtained under hydrothermal conditions either by oven heat or microwave irradiation. The anhydrous compounds containing La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, and Ho, are isostructural. However, the compounds based on Y, Er, Tm, Yb, and Lu are hydrated and their structures have not yet been solved. The series of compounds are characterized by PXRD, TEM, SEM-EDX and thermal analyses (TG-MS and DSC). TEM study show a variable particles size with a minimum mean-particle size of ca. 30 nm. These compounds exhibit unusual very high thermal stability. The size of particles and the thermal stability are depending on lanthanide(III) cation features. All the investigated materials show paramagnetic behaviour. The magnetic susceptibility data follow a Curie-Weiss laws with paramagnetic effective moments in good agreement with those expected for Ln{sup 3+} free ions.

Peculiarity of component interaction in {l_brace}Y, Dy{r_brace}-Mn-Sn ternary systems

Energy Technology Data Exchange (ETDEWEB)

Romaka, V.V. [Department of Materials Engineering and Applied Physics, Lviv Polytechnic National University, Ustyyanovycha Str. 5, 79013 Lviv (Ukraine); Konyk, M. [Inorganic Chemistry Department, Ivan Franko Lviv National University, Kyryla and Mefodiya Str. 6, 79005 Lviv (Ukraine); Romaka, L., E-mail: romakal@franko.lviv.ua [Inorganic Chemistry Department, Ivan Franko Lviv National University, Kyryla and Mefodiya Str. 6, 79005 Lviv (Ukraine); Pavlyuk, V. [Inorganic Chemistry Department, Ivan Franko Lviv National University, Kyryla and Mefodiya Str. 6, 79005 Lviv (Ukraine); Jan Dlugosz University, Institute of Chemistry, Environmental Protection and Biotechnology, al. Armii Krajowej 13/15, 42200 Czestochowa (Poland); Ehrenberg, H. [Institute for Complex Materials, IFW Dresden, Helmholtzstrasse 20, D-01069 Dresden (Germany); Tkachuk, A. [Inorganic Chemistry Department, Ivan Franko Lviv National University, Kyryla and Mefodiya Str. 6, 79005 Lviv (Ukraine)

2011-07-14

Highlights: > {l_brace}Y, Dy{r_brace}-Mn-Sn ternary systems at 770 K are characterized by formation of stannides with general compositions RMn{sub 6}Sn{sub 6} and R{sub 4}Mn{sub 4}Sn{sub 7}. > The crystal structure of YMn{sub 6}Sn{sub 6} was determined by single crystal and powder diffraction methods. > Structural analysis showed that Dy{sub 4}Mn{sub 4}Sn{sub 7} compound is disordered. > Isostructural R{sub 4}Mn{sub 4}Sn{sub 7} compounds were also found with Gd, Tb, Ho, Er, Tm(confirmed), Yb, and Lu. - Abstract: The phase equilibria in the Y-Mn-Sn and Dy-Mn-Sn ternary systems were studied at 770 K by means of X-ray and metallographic analyses in the whole concentration range. Both Y-Mn-Sn and Dy-Mn-Sn systems are characterized by formation of two ternary compounds RMn{sub 6}Sn{sub 6} (MgFe{sub 6}Ge{sub 6}-type, space group P6/mmm) and R{sub 4}Mn{sub 4}Sn{sub 7} (Zr{sub 4}Co{sub 4}Ge{sub 7}-type, space group I4/mmm). The disorder in Dy{sub 4}Mn{sub 4}Sn{sub 7} compound was found by single crystal method. Compounds with the same type of structure were also found with Gd, Tb, Ho, Er, Tm (confirmed), Yb, and Lu and their lattice parameters were determined.

LuFLA1PRO and LuBGAL1PRO promote gene expression in the phloem fibres of flax (Linum usitatissimum).

Science.gov (United States)

Hobson, Neil; Deyholos, Michael K

2013-04-01

Cell type-specific promoters were identified that drive gene expression in an industrially important product. To identify flax (Linum usitatissimum) gene promoters, we analyzed the genomic regions upstream of a fasciclin-like arabinogalactan protein (LuFLA1) and a beta-galactosidase (LuBGAL1). Both of these genes encode transcripts that have been found to be highly enriched in tissues bearing phloem fibres. Using a beta-glucuronidase (GUS) reporter construct, we found that a 908-bp genomic sequence upstream of LuFLA1 (LuFLA1PRO) directed GUS expression with high specificity to phloem fibres undergoing secondary cell wall development. The DNA sequence upstream of LuBGAL1 (LuBGAL1PRO) likewise produced GUS staining in phloem fibres with developing secondary walls, as well as in tissues of developing flowers and seed bolls. These data provide further evidence of a specific role for LuFLA1 in phloem fibre development, and demonstrate the utility of LuFLA1PRO and LuBGAL1PRO as tools for biotechnology and further investigations of phloem fibre development.

Separation and implantation of the rare isotope {sup 163}Ho

Energy Technology Data Exchange (ETDEWEB)

Kieck, Tom; Chrysalidis, Katerina; Dorrer, Holger; Kormannshaus, Stefan; Schmidt, Sebastian; Schneider, Fabian; Wendt, Klaus [JGU Mainz (Germany); Duellmann, Christoph [JGU Mainz (Germany); GSI Darmstadt (Germany); Gamer, Lisa; Gastaldo, Loredana [Universitaet Heidelberg (Germany); Collaboration: ECHo-Collaboration

2016-07-01

The ECHo collaboration aims at measuring the electron neutrino mass by recording the spectrum following electron capture of {sup 163}Ho. To reach a sub-eV sensitivity, a large number of individual microcalorimeters is needed, into which the isotope must be implanted in a well-controlled manner. The necessary amount of {sup 163}Ho is produced by neutron irradiation of enriched {sup 162}Er in the ILL high flux reactor. This introduces significant contaminations of other radioisotopes, which have to be quantitatively removed both, by chemical and mass spectrometric separation. The application of resonance ionization at the RISIKO mass separator guarantees the required isotope selectivity for purification and suitable energy for ion implantation. The efficiency and stability of the laser ion source was improved by Finite-Element Analysis of the thermal processes. For optimum implantation into the detector pixels (170 x 170 μm{sup 2}) with minimum losses a small ion beam spot at the implantation site is needed. For this purpose, post focusing ion optics were installed. Simulations were performed in order to optimize the homogeneous distribution of the implanted ions. The necessity to alternate implantation phases with deposition of a thin metallic layer for {sup 163}Ho activities larger than 10 Bq is being discussed.

Buffer layers and articles for electronic devices

Science.gov (United States)

Paranthaman, Mariappan P.; Aytug, Tolga; Christen, David K.; Feenstra, Roeland; Goyal, Amit

2004-07-20

Materials for depositing buffer layers on biaxially textured and untextured metallic and metal oxide substrates for use in the manufacture of superconducting and other electronic articles comprise RMnO.sub.3, R.sub.1-x A.sub.x MnO.sub.3, and combinations thereof; wherein R includes an element selected from the group consisting of La, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, and Y, and A includes an element selected from the group consisting of Be, Mg, Ca, Sr, Ba, and Ra.

Spectrographic determination of lanthanides in high-purity uranium compounds, after chromatographic separation by alumina-hydrofluoric acid

International Nuclear Information System (INIS)

Lordello, A.R.; Abrao, A.

1979-01-01

A method is presented for the determination of fourteen rare earth elements in high-purity uranium compounds by emission spectrography. The rare earths are chromatographically separated from uranium by using alumina-hydrofluoric acid. Lanthanum is used both as collector and internal standard. The technique of excitation involves a total consumption of the sample in a 17 ampere direct current arc. The range of determination is about 0.005 to 0.5 μg/g uranium. The coefficient of variation for Pr, Ho, Dy, Er, Tm, Lu, Gd and Tb amounts to 10%. (Author) [pt

Thiocarbomide coordination compounds of yttrium subgroup rare earth chlorides

International Nuclear Information System (INIS)

Sakharova, Yu.G.; Perov, V.N.; Loginov, V.I.

1978-01-01

Thiocarbamide coordination compounds of chlorides of elements of the yttrium subgroup 4MeCl 3 x5Cs(NH 2 ) 2 x2OH 2 O (where Me stands for Tb, Dy, Ho, Er, Tm, Yb, Lu, Y) were produced for the first time. The compounds obtained are stable in air, have definite melting points, are highly soluble in methyl and ethyl alcohols, and are unstable in water. They recrystallize from ethyl alcohol without changing their chemical composition. The identity of these compounds was confirmed by X-ray analysis

Multicolor upconversion emission of dispersed ultrasmall cubic Sr2LuF7 nanocrystals synthesized by a solvothermal process

International Nuclear Information System (INIS)

Gong, Lunjun; Ma, Mo; Xu, Changfu; Li, Xujun; Wang, Suiping; Lin, Jianguo; Yang, Qibin

2013-01-01

Lanthanide (Ln 3+ ) doped Sr 2 LuF 7 (Ln 3+ =Er 3+ /Tm 3+ /Yb 3+ ) nanocrystals (NCs) were synthesized via a solvothermal process using oleate as stabilizing agent. The as-synthesized NCs with a mean diameter of sub-20 nm can be well dispersed in cyclohexane and show a pure cubic phase structure with space group Fm3 ¯ m. Following appropriate lanthanide ion doping, the NCs show intense red, green, blue and white-color upconversion emission (UC) under the excitation of a 980 nm laser. Predominant near-infrared UC can also be obtained in the Yb 3+ /Tm 3+ doped Sr 2 LuF 7 NCs. The energy transfer UC mechanisms for the fluorescent intensity were also investigated. The desirable property of the ultrasmall dispersed NCs makes them promising materials for the applications in miniaturized solid-state light sources, multicolor three-dimensional display devices and fluorescent labels for biomedical imaging. - Highlights: ► Cubic-structure (Fm3 ¯ m) Sr 2 LuF 7 nanocrystals were synthesized for the first time. ► Nanocrystals (sub-20 nm) with cubic or spherical shape can be well dispersed. ► By doping properly, the nanocrystals show intense multicolor upconversion. ► Predominant near-infrared upconversion can be obtained in Sr 2 LuF 7 nanocrystals. ► Upconversion mechanism for the fluorescent intensity is mainly energy transfer.

radiolabeling of DOTA-substance P with 177Lu and biodistribution of 177Lu-DOTA-substance P

International Nuclear Information System (INIS)

Liang Jixin; Li Hongyu; Xiang Xueqin; Luo Zhifu; Luo Hongyi; Hu Liansheng; Chen Yang; Zhuang Ling; Deng Xinrong

2012-01-01

The aim of this project is to evaluate the biodistribution of 177 Lu-DOTA-SP in normal mice and in PANC-1 tumor bearing nude mice and to pave the way for its potentially medical application. In this study, 177 Lu-DOTA-SP was successfully prepared with labeling yield of greater than 90% at optimized conditions and more than 98% of radiochemical purity after C18 Sep-Pak purification. 177 Lu-DOTA-SP showed good stability in saline and in 5% serum while it decomposed slowly in 10% serum. Biodistribution studies in normal mice showed high uptake of 177 Lu-DOTA-SP in the kidneys, indicating the excretion mainly by renal pathway. In addition, 177 Lu-DOTA-SP was washed out from the blood quickly. Bio- distribution of 177 Lu-DOTA-SP in PANC-1 tumor bearing mice showed higher uptake in pancreatic tumor than that in normal pancreas, indicating the presence of NK-1 receptors in PANC-1 pancreatic tumor. However, from SPECT image, no radioactivity accumulation was observed in PANC-1 tumor. Further evaluation is needed to confirm its potential application for radiotherapy of pancreatic cancers. (authors)

Easy and General Synthesis of Large-Sized Mesoporous Rare-Earth Oxide Thin Films by 'Micelle Assembly'.

Science.gov (United States)

Li, Yunqi; Bastakoti, Bishnu Prasad; Imura, Masataka; Dai, Pengcheng; Yamauchi, Yusuke

2015-12-01

Large-sized (ca. 40 nm) mesoporous Er2O3 thin films are synthesized by using a triblock copolymer poly(styrene-b-2-vinyl pyridine-b-ethylene oxide) (PS-b-P2VP-b-PEO) as a pore directing agent. Each block makes different contributions and the molar ratio of PVP/Er(3+) is crucial to guide the resultant mesoporous structure. An easy and general method is proposed and used to prepare a series of mesoporous rare-earth oxide (Sm2O3, Dy2O3, Tb2O3, Ho2O3, Yb2O3, and Lu2O3) thin films with potential uses in electronics and optical devices. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Competing effects in the magnetic polarization of non-magnetic atoms

International Nuclear Information System (INIS)

Boada, R; Piquer, C; Chaboy, J; Laguna-Marco, M A

2013-01-01

The magnetic polarization of the Lu 5d states through the Ho 1-x Lu x (Fe 1-y Al y ) 2 series has been studied by means of x-ray magnetic circular dichroism. A combined study of the dichroic signals performed at the Fe K-, Ho L 2 - and Lu L 2,3 -edges gives a complete picture of the polarization scheme at the conduction band. The results show that in the presence of competing localized magnetic moments, μ Fe (3d) and μ Ho (4f), the dichroic signal at the Lu site is mainly due to the Fe atoms, the effect of the magnetic rare-earth being negligible. Estimation of the spin and orbital components of the Lu(5d) induced magnetic moment have been obtained by applying the magneto-optical sum rules derived for x-ray magnetic circular dichroism.

„Knowledge is power“: Studium MBA v perspektivě Bourdieuho teorie kapitálů/ “Knowledge is power”: MBA study program in Bourdieu’s perspective of capitals

Directory of Open Access Journals (Sweden)

Jana Dvořáčková

2015-01-01

Full Text Available Cílem této empirické studie, která vychází z ročního etnografického výzkumu na soukromé vysoké škole, je analyzovat, jaký význam má studijní program MBA v reprodukci sociálních diferencí. V první části je představeno teoretické pozadí studie, jímž jsou Bourdieuho koncepty kulturního, ekonomického, symbolického a sociálního kapitálu a jeho pojetí mechanismu sociální reprodukce skrze školské instituce. Druhá část příspěvku přibližuje klíčové rysy soukromé vysoké školy, kde se výzkum realizoval. Třetí část je věnována analýze manifestních cílů MBA programu, jímž je posílit kulturní a ekonomický kapitál studujících – rozvíjet jejich znalosti, kariérní perspektivy i úspěchy v podnikání. Vedle toho se zabývá MBA studiem coby zdrojem symbolického i sociálního kapitálu. Jak text ukazuje, MBA program je vedle prostředku získávání znalostí a dovedností současně prostorem konverze ekonomického kapitálu do kapitálu symbolického a sociálního. Ty následně zvyšují objem ekonomického kapitálu studujících, čímž dále upevňují jejich sociální pozici.

Blood clearance and occupational exposure for {sup 177}Lu-DOTATATE compared to {sup 177}Lu-PSMA radionuclide therapy

Energy Technology Data Exchange (ETDEWEB)

Abuqbeitah, Mohammad; Demir, Mustafa; Uslu-Besli, Lebriz; Yeyin, Nami; Soenmezoglu, Kerim [Istanbul University, Department of Nuclear Medicine, Cerrahpasa Faculty of Medicine, Istanbul (Turkey)

2018-03-15

The main target of this work is to examine blood clearance and external exposure for {sup 177}Lu-DOTATATE compared with new emerging {sup 177}Lu-PSMA therapy. Blood clearance and radiation exposure of 31 patients treated with 5.5 ± 1.1 GBq {sup 177}Lu-DOTATATE were compared to those of 23 patients treated with 7.4 GBq {sup 177}Lu-PSMA. Dose rates were measured at several distances and time points up to 120 h after treatment. Blood samples were collected conjunctively after infusion. Caregiver's cumulative dose was measured by means of an OSL (optically stimulated luminescence) dosimeter for 4-5 days and medical staff's dose was also estimated using electronic personal dosimeters. Finger dose was determined via ring TLD (Thermoluminescence Dosimeter) for radiopharmacists and nurses. Dose rates due to {sup 177}Lu-DOTATATE at a distance of 1 m, 4 h and 6 h after infusion, were 3.0 ± 2.8 and 2 ± 1.9 μSv/(h GBq), respectively, while those due to {sup 177}Lu-PSMA were 3.1 ± 0.8 and 2.2 ± 0.9 μSv/(h GBq). Total effective dose of 17 caregivers was 100-200 μSv for {sup 177}Lu-DOTATATE therapy. Mean effective doses to nurses and radiopharmacists were 5 and 4 μSv per patient, respectively, while those for physicists and physicians were 2 μSv per patient. For {sup 177}Lu-DOTATATE, effective half-life in blood and early elimination phase were 0.31 ± 0.13 and 4.5 ± 1 h, while they were found as 0.4 ± 0.1 and 5 ± 1 h, respectively, for {sup 177}Lu-PSMA. The first micturition time following {sup 177}Lu-DOTATATE infusion was noted after 36 ± 14 min, while the second and third voiding times were after 74 ± 9 and 128 ± 41 min, respectively. It is concluded that blood clearance and radiation exposure for {sup 177}Lu-DOTATATE are very similar to those for {sup 177}Lu-PSMA, and both treatment modalities are reasonably reliable for outpatient treatment, since the mean dose rate [2.1 μSv/(h GBq)] decreased below the dose rate that allows release of the patient

Completing the series. New coordination networks of composition {sup 3}{sub ∞}[RE{sub 2}(ADC){sub 3}(H{sub 2}O){sub 6}].2H{sub 2}O with RE = Pr, Nd, Sm, Eu, Tb, Dy, Ho, Er, Y and ADC{sup 2-} = acetylenedicarboxylate ({sup -}O{sub 2}C-C≡C-CO{sub 2}{sup -})

Energy Technology Data Exchange (ETDEWEB)

Gramm, Verena K.; Schuy, Andrea; Ruschewitz, Uwe [Institut fuer Anorganische Chemie, Koeln Univ. (Germany); Suta, Markus; Wickleder, Claudia [Anorganische Chemie, Universitaet Siegen (Germany); Sternemann, Christian [Fakultaet Physik / DELTA, Technische Universitaet Dortmund (Germany)

2018-02-01

The crystal structures of {sup 3}{sub ∞}[RE{sub 2}(ADC){sub 3}(H{sub 2}O){sub 6}].2H{sub 2}O (RE = Pr, Nd, Sm, Eu, Tb, Dy) were solved and refined from X-ray single crystal data. They crystallize in a structure type already known for RE = La, Ce and Gd (P1, no. 2, Z = 2), which is characterized by REO{sub 9} polyhedra forming dimeric units being the nodes of a 3D framework structure linked by ADC{sup 2-} anions ({sup -}O{sub 2}C-C≡C-CO{sub 2}{sup -} = acetylenedicarboxylate). From synchrotron powder diffraction data it was shown that isostructural coordination networks are formed for RE = Ho, Er, Y, whereas for RE = Tm, Yb, Lu a new structure type crystallizing in a highly complex crystal structure with a large orthorhombic unit cell is found. All compounds are obtained by slow evaporation of an aqueous solution containing RE(OAc){sub 3}.xH{sub 2}O and acetylenedicarboxylic acid (H{sub 2}ADC). The coordination networks of composition {sup 3}{sub ∞}[RE{sub 2}(ADC){sub 3}(H{sub 2}O){sub 6}].2H{sub 2}O were thoroughly investigated by thermal analysis and for RE = Eu, Tb, a strong red and green photoluminescence was observed and investigated by means of UV/Vis spectroscopy. (copyright 2018 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

Investigation of neutron-rich rare-earth nuclei including the new isotopes 177Tm and 184Lu

International Nuclear Information System (INIS)

Rykaczewski, K.; Gippert, K.L.; Runte, E.; Schmidt-Ott, W.D.; Tidemand-Petersson, P.; Kurcewicz, W.; Nazarewicz, W.

1989-01-01

Decays of neutron-rich isotopes in the rare-earth region were studied by means of on-line mass separation and β-γ spectroscopy using multinucleon-transfer reactions between beams of 136 Xe (9 and 11.7 MeV/u), 186 W (11.7 and 15 MeV/u) and 238 U (11.4 MeV/u) and targets of nat W and Ta. The higher beam energies appear to be advantageous for the production of such isotopes. Two new isotopes were identified: 177 Tm with a half-life T 1/2 = 85±10/15 s, and 184 Lu with T 1/2 ≅ 18 s. A new 47 s-activity found at A = 171 is tentatively assigned to the decay of the new isotope 171 Ho. The properties of the ground and excited states of neutron-rich lanthanide isotopes are interpreted within the shell model using the deformed Woods-Saxon potential. A change of the ground-state configuration for odd-mass neutron-rich lutetium isotopes from π 7/2 + [404] to π 9/2 - [514] is suggested, this change being due to the influence of a large hexadecapole deformation. The role of a possible isometric state in 180 Lu for the nucleosynthesis of 180m Ta is discussed. (orig.)

Er:YAG pre-treatment for bonding of orthodontic bracket: 1 year of in vitro treatment

Directory of Open Access Journals (Sweden)

de Jesus Tavarez RR

2017-03-01

Full Text Available Rudys Rodolfo de Jesus Tavarez,1 Gisele Lima Bezerra,2 Karla Janilee de Souza Penha,3 Carlos Rocha Gomes Torres,4 Leily Macedo Firoozmand5 1Department of Dentistry, Ceuma University (UNICEUMA, 2Dentistry Program, Ceuma University (UNICEUMA, 3Dentistry Program, Federal University of Maranhão, UFMA, São Luís, MA, 4Restorative Dentistry Department, ICT UNESP University, São Paulo, 5Dentistry Department I, Federal University of Maranhão,UFMA, São Luís, MA, Brazil Objective: The aim of this study was to evaluate in vitro bond strength of metal brackets bonded with: total etch, total etch with erbium: yttrium aluminum garnet laser (Er:YAG and self-etching adhesive systems, submitted to thermal-mechanical cycling, simulating 1 year of orthodontic treatment.Materials and methods: For the study, 80 bovine incisors were randomly divided into 3 experimental groups (n=16 each: XT- acid etching + Transbond XT, XT/Er:YAG- Transbond XT associated with Er:YAG laser irradiation (λ=2.94 μm, 60 mJ, 10 Hz and SEP- Transbond Plus Self Etching Primer. Samples were submitted to thermal-mechanical cycling, simulating 1 year of orthodontic treatment. Afterward, the shear bond strength test was performed in a universal test machine at a speed of 0.5mm/min. Samples were evaluated under a stereomicroscope and by scanning electron microscopy for analysis of enamel surface and adhesive remnant index. Data were analyzed using Kruskal–Wallis and Mann–Whitney (with Bonferroni correction statistical tests.Results: Statistically significant difference was observed between the groups studied (p<0.05. Groups XT and SEP showed the highest bond strength values, without statistical difference between them, while group XT/Er:YAG showed reduction in bond strength values. Higher frequency of adhesive failures between enamel and adhesive system was verified for groups XT and XT/Er:YAG.Conclusion: The conventional (XT and self-etching (SEP adhesive systems showed mean bond

Late night activity regarding stroke codes: LuNAR strokes.

Science.gov (United States)

Tafreshi, Gilda; Raman, Rema; Ernstrom, Karin; Rapp, Karen; Meyer, Brett C

2012-08-01

There is diurnal variation for cardiac arrest and sudden cardiac death. Stroke may show a similar pattern. We assessed whether strokes presenting during a particular time of day or night are more likely of vascular etiology. To compare emergency department stroke codes arriving between 22:00 and 8:00 hours (LuNAR strokes) vs. others (n-LuNAR strokes). The purpose was to determine if late night strokes are more likely to be true strokes or warrant acute tissue plasminogen activator evaluations. We reviewed prospectively collected cases in the University of California, San Diego Stroke Team database gathered over a four-year period. Stroke codes at six emergency departments were classified based on arrival time. Those arriving between 22:00 and 8:00 hours were classified as LuNAR stroke codes, the remainder were classified as 'n-LuNAR'. Patients were further classified as intracerebral hemorrhage, acute ischemic stroke not receiving tissue plasminogen activator, acute ischemic stroke receiving tissue plasminogen activator, transient ischemic attack, and nonstroke. Categorical outcomes were compared using Fisher's Exact test. Continuous outcomes were compared using Wilcoxon's Rank-sum test. A total of 1607 patients were included in our study, of which, 299 (19%) were LuNAR code strokes. The overall median NIHSS was five, higher in the LuNAR group (n-LuNAR 5, LuNAR 7; P=0·022). There was no overall differences in patient diagnoses between LuNAR and n-LuNAR strokes (P=0·169) or diagnosis of acute ischemic stroke receiving tissue plasminogen activator (n-LuNAR 191 (14·6%), LuNAR 42 (14·0%); P=0·86). Mean arrival to computed tomography scan time was longer during LuNAR hours (n-LuNAR 54·9±76·3 min, LuNAR 62·5±87·7 min; P=0·027). There was no significant difference in 90-day mortality (n-LuNAR 15·0%, LuNAR 13·2%; P=0·45). Our stroke center experience showed no difference in diagnosis of acute ischemic stroke between day and night stroke codes. This

Spectroscopy and microchip laser operation of Tm, Ho:KYW crystals with different Ho concentrations

Science.gov (United States)

Gusakova, N. V.; Kurilchik, S. V.; Yasukevich, A. S.; Kisel, V. E.; Dashkevich, V. I.; Orlovich, V. A.; Pavlyuk, A. A.; Vatnik, S. M.; Bagaev, S. N.; Kuleshov, N. V.

2018-02-01

The spectroscopic properties of Tm, Ho:KYW crystals with different Ho concentrations were investigated. The diode-pumped microchip laser operation of Tm (5 at.%), Ho (0.5 at.%):KYW and Tm (5 at.%), Ho (1 at.%):KYW was demonstrated. The highest, to our knowledge, output power of 480 mW with slope efficiency of 31% for CW Tm (5 at.%), Ho (0.5 at.%):KYW microchip laser was obtained.

Adhesive activity of Lu glycoproteins is regulated by interaction with spectrin

Energy Technology Data Exchange (ETDEWEB)

An, Xiuli; Gauthier, Emilie; Zhang, Xihui; Guo, Xinhua; Anstee, David; Mohandas, Narla; Anne Chasis, Joel

2008-03-18

The Lutheran (Lu) and Lu(v13) blood group glycoproteins function as receptors for extracellular matrix laminins. Lu and Lu(v13) are linked to the erythrocyte cytoskeleton through a direct interaction with spectrin. However, neither the molecular basis of the interaction nor its functional consequences have previously been delineated. In the present study, we defined the binding motifs of Lu and Lu(v13) on spectrin and identified a functional role for this interaction. We found that the cytoplasmic domains of both Lu and Lu(v13) bound to repeat 4 of the spectrin chain. The interaction of full-length spectrin dimer to Lu and Lu(v13) was inhibited by repeat 4 of {alpha}-spectrin. Further, resealing of this repeat peptide into erythrocytes led to weakened Lu-cytoskeleton interaction as demonstrated by increased detergent extractability of Lu. Importantly, disruption of the Lu-spectrin linkage was accompanied by enhanced cell adhesion to laminin. We conclude that the interaction of the Lu cytoplasmic tail with the cytoskeleton regulates its adhesive receptor function.

Optical properties of Mg2+, Yb3+, and Ho3+ tri-doped LiNbO3 crystals

Science.gov (United States)

Dai, Li; Liu, Chun-Rui; Tan, Chao; Yan, Zhe-Hua; Xu, Yu-Heng

2017-04-01

A series of LiNbO3 crystals tri-doped with Mg{}2+, Yb{}3+, and Ho{}3+ are grown by the conventional Czochraski technique. The concentrations of Mg{}2+, Yb{}3+, and Ho{}3+ ions in Mg:Yb:Ho:LiNbO3 crystals are measured by using an inductively coupled plasma atomic emission spectrometry. The x-ray diffraction is proposed to determine the lattice constant and analyze the internal structure of the crystal. The light-induced scattering of Mg:Yb:Ho:LiNbO3 crystal is quantitatively described via the threshold effect of incident exposure energy flux. The exposure energy ({E}{{r}}) is calculated to discuss the optical damage resistance ability. The exposure energy of Mg(7 mol):Yb:Ho:LiNbO3 crystal is 709.17 J/cm2, approximately 425 times higher than that of the Mg(1 mol):Yb:Ho:LiNbO3 crystal in magnitude. The blue, red, and very intense green bands of Mg:Yb:Ho:LiNbO3 crystal are observed under the 980-nm laser excitation to evaluate the up-conversion emission properties. The dependence of the emission intensity on pumping power indicates that the up-conversion emission is a two-photon process. The up-conversion emission mechanism is discussed in detail. This study indicates that Mg:Yb:Ho:LiNbO3 crystal can be applied to the fabrication of new multifunctional photoluminescence devices. Project supported by the National Natural Science Foundation of China (Grant No. 51301055), the Youth Science Fund of Heilongjiang Province, China (Grant No. QC2015061), the Special Funds of Harbin Innovation Talents in Science and Technology Research, China (Grant No. 2015RQQXJ045 ), and the Science Funds for the Young Innovative Talents of Harbin University of Science and Technology, China (Grant No. 201501).

Study of the production of {sup 177}Lu through {sup 176}Yb (n, {gamma}) {sup 177}Yb {yields} {sup 177}Lu nuclear reaction

Energy Technology Data Exchange (ETDEWEB)

Silva, Giovana Pasqualini da; Osso Junior, Joao Alberto [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)]. E-mail: gpsilva@ipen.br; jaosso@ipen.br

2007-07-01

The beta minus emitter {sup 177}Lu is a promising therapeutic radioisotope for the curative treatment of cancer using labelled proteins. It has a half - life of T{sub 1/2} = 6.71 day and maximum and average {beta}{sup -} energies of 421 and 133 keV, resulting in a short range of radiation in tissue. The decay is accompanied by the emission of low energy {gamma}-radiation with 208.3 keV (11%) and 113 keV (6.4%) suitable for simultaneous imaging, {sup 177}Lu can be produced by two different routes, namely, by irradiation of natural Lu{sub 2}O{sub 3} target ({sup 176}Lu, 2.6%) or enriched (in {sup 176}Lu) Lu{sub 2}O{sub 3} target, as also by irradiation of Yb target (Yb{sub 2}O{sub 3}) followed by radiochemical separation of {sup 177}Lu from Yb isotopes. The objective of this work is to study the production of {sup 177}Lu through the indirect {sup 176}Yb(n,{gamma}){sup 177}Yb {yields} {sup 177}Lu nuclear reaction. The results of the production yield of {sup 177}Lu will be shown and compared with the direct reaction. The method of choice for the chemical separation between Lu and Yb was the ion exchange, using an cation exchange resin in Cl{sup -} form and {alpha}-HIBA as eluent. Preliminary results showed a good separation of {sup 177}Lu from Yb{sub 2}O{sub 3} indirect targets. (author)

Comparison of Spectral and Scintillation Properties of LuAP:Ce and LuAP:Ce,Sc Single Crystals

Science.gov (United States)

Petrosyan, Ashot G.; Derdzyan, Marina; Ovanesyan, Karine; Shirinyan, Grigori; Lecoq, Paul; Auffray, Etiennette; Kronberger, Matthias; Frisch, Benjamin; Pedrini, Christian; Dujardin, Christophe

2009-10-01

Scintillation properties of LuAP:Ce and LuAP:Ce,Sc crystal series were studied under excitation by gamma-rays from a 137Cs source. Both series demonstrated comparable optical quality in terms of underlying absorption at 260 nm, slope of the optical edge and transmission in the range of emission. The light yield of LuAP:Ce crystals measured in 0.2 cm times 0.2 cm times 0.8 cm pixels increases linearly with the Ce concentration reaching at 0.58 at. % 6448 plusmn 322 ph/MeV and 9911 plusmn 496 ph/MeV in the long and in the short directions respectively (the light yield ratio is 65%) and shows no sign of light saturation. The energy resolution is found to depend, among other factors, on the uniformity of Ce concentration within the pixels and is improved to 7.1 plusmn 0.4% (I = 0.2 cm), 9.5 plusmn 0.5% (I = 0.8 cm). Intentional co-doping with Sc + ions was tested and resulted in increase of the Ce distribution coefficient to about 0.3. This enabled to increase the concentration of Ce in LuAP:Ce,Sc crystals up to 0.7 at. %, while conserving high optical quality. In contrast to LuAP:Ce, the light yield in LuAP:Ce,Sc crystals does not increase with Ce concentration, the photo peak being gradually suppressed. The involved mechanisms are discussed basing on measurements of the unit cell volumes, Ce concentration uniformity, x-ray rocking spectra, absorption spectra of pure and variously doped LuAP crystals, and emission spectra under different excitations.

High spin K isomeric target of 177mLu

International Nuclear Information System (INIS)

Roig, O.; Belier, G.; Daugas, J.-M.; Delbourgo, P.; Maunoury, L.; Meot, V.; Morichon, E.; Sauvestre, J.-E.; Aupiais, J.; Boulin, Y.; Fioni, G.; Letourneau, A.; Marie, F.; Ridikas, D.

2004-01-01

The techniques used to produce a 177m Lu (J π =23/2 - ,T 1/2 =160.4 days) target are described in this paper. Firstly, an isotopic separation of an enriched lutetium sample was used to reach a purity of 176 Lu close to 99.993%. Afterwards, the high neutron flux of the Grenoble Institut Laue-Langevin reactor was used to produce the 177m Lu isomer by the 176 Lu(n,γ) reaction. Finally, a chemical separation was performed to extract 10 13 nuclei of 177m Lu. Thanks to this experiment, we have been able to estimate the destruction cross-section of the 177m Lu

Ternary silicides ScIr{sub 4}Si{sub 2} and RERh{sub 4}Si{sub 2} (RE = Sc, Y, Tb-Lu) and quaternary derivatives RERh{sub 4}Si{sub 2-x}Sn{sub x} (RE = Y, Nd, Sm, Gd-Lu) - structure, chemical bonding, and solid state NMR spectroscopy

Energy Technology Data Exchange (ETDEWEB)

Vosswinkel, Daniel; Benndorf, Christopher; Poettgen, Rainer [Muenster Univ. (Germany). Inst. fuer Anorganische und Analytische Chemie; Eckert, Hellmut [Muenster Univ. (Germany). Inst. fuer Physikalische Chemie; Sao Paulo Univ., Sao Carlos (Brazil). Inst. of Physics; Matar, Samir F. [Bordeaux Univ., CNRS, ICMCB, UPR 9048, Pessac (France)

2016-11-01

The silicides ScIr{sub 4}Si{sub 2} and RERh{sub 4}Si{sub 2} (RE = Sc, Y, Tb-Lu) and silicide stannides RERh{sub 4}Si{sub 2-x}Sn{sub x}(RE = Y, Nd, Sm, Gd-Lu) were synthesized from the elements by arc-melting and subsequent annealing. The new compounds crystallize with the orthorhombic YRh{sub 4}Ge{sub 2} type structure, space group Pnma. They were characterized by X-ray powder patterns and several structures were refined from single crystal X-ray diffractometer data. The main structural motifs of this series of silicides are tricapped trigonal prisms formed by the transition metal and rare earth atoms. One of the two crystallographically independent silicon sites allows for formation of solid solutions with tin, exemplarily studied for ErRh{sub 4}Si{sub 2-x}Sn{sub x}. Electronic structure calculations reveal strong covalent Rh-Si bonding as the main stability factor. Multinuclear ({sup 29}Si, {sup 45}Sc, and {sup 89}Y) magic-angle spinning (MAS) NMR spectra of the structure representatives with diamagnetic rare-earth elements (Sc, Y, Lu) are found to be consistent with the crystallographic data and specifically confirm the selective substitution of Sn in the Si2 sites in the quaternary compounds YRh{sub 4}SiSn and LuRh{sub 4}SiSn.

Alternative method to determine Specific Activity of (177)Lu by HPLC.

Science.gov (United States)

Breeman, Wouter A P; de Zanger, Rory M S; Chan, Ho Sze; de Blois, Erik

2015-01-01

Peptide Receptor Radionuclide Therapy (PRRT) with (177)Lu-DOTA-peptides requires (177)Lu with high specific activity (SA) and values >740 GBq (177)Lu per mg Lu to maximise the atom% of (177)Lu over total Lu. Vendors provide SA values which are based on activity and mass of the target, whereas due to "burn-up" of target, these SA values are not accurate. For a radiochemist the SA of (177)Lu is of interest prior to radiolabeling. An alternative method to determine SA was developed by HPLC, which includes a metal titration of a known amount of DOTA-peptide with a known amount of activity ((177)Lu), and a unknown amount of metal ((177+nat)Lu). Based on an HPLC separation of radiometal-DOTA-peptide and DOTA-peptide, and the concordant ratio of these components the metal content ((177+nat)Lu) can be calculated, and eventually the SA of (177)Lu can be accurately determined. These experimentally determined SA values exceeded the estimated values provided by vendors by 27 ± 16%, (range 6-73 %). The deviation of SA values for samples from the same Lu batch was <2% (n ≥ 10). the SA of (177)Lu is apparently often higher as stated by vendors in comparison to the experimentally determined actual values. For this reason, the SA of (177)Lu-DOTA-TATE and other Lu-DOTA-peptides could be increased accordingly.

LiHo(PO34

Directory of Open Access Journals (Sweden)

Mokhtar Férid

2009-02-01

Full Text Available Lithium holmium(III polyphosphate(V, LiHo(PO34, belongs to the type I of polyphosphates with general formula ALn(PO34, where A is a monovalent cation and Ln is a trivalent rare earth cation. In the crystal structure, the polyphosphate chains spread along the b-axis direction, with a repeat period of four tetrahedra and 21 internal symmetry. The Li and Ho atoms are both located on twofold rotation axes and are surrounded by four and eight O atoms, leading to a distorted tetrahedral and dodecahedral coordination, respectively. The HoO8 polyhedra are isolated from each other, the closest Ho...Ho distance being 5.570 (1 Å.

Hybrid synchronization of hyperchaotic Lu system

Indian Academy of Sciences (India)

In this paper, we study the hybrid synchronization between two identical hyperchaotic Lu systems. Hybrid synchronization of hyperchaotic Lu system is achieved through synchronization of two pairs of states and anti-synchronization of the other two pairs of states. Active controls are designed to achieve hybrid ...

İki uçlu bozukluk 1 ve iki uçlu bozukluk 2 depresyon tedavisi arasındaki farklar

OpenAIRE

Sayar, Kemal

2013-01-01

İki uçlu bozukluk 1 ve 2 depresyonları, klinik açıdan farklılıklar gösterebilmektedir. İki uçlu bozukluk 2 ve iki uçlu bozukluk 1 depresyonların tedavisi arasındaki farklar ise tartışmalı bir alandır. Henüz İki uçlu bozukluk 2 depresyon tedavisi konusunda yeterince kanıt birikmemişse de ilk veriler her iki durumun tedavisinde farklar olması gerektiğini düşündürmektedir. Özellikle antidepresan kullanımı konusunda dikkatli olmak gerekmektedir.

The Bad Berka dose protocol: comparative results of dosimetry in peptide receptor radionuclide therapy using (177)Lu-DOTATATE, (177)Lu-DOTANOC, and (177)Lu-DOTATOC.

Science.gov (United States)

Schuchardt, Christiane; Kulkarni, Harshad R; Prasad, Vikas; Zachert, Carolin; Müller, Dirk; Baum, Richard P

2013-01-01

The objective of this study is to analyze the in vivo behavior of the (177)Lu-labeled peptides DOTATATE, DOTANOC, and DOTATOC used for peptide receptor radionuclide therapy (PRRNT) of neuroendocrine tumors (NETs), by measuring organ and tumor kinetics and by performing dosimetric calculations. Two hundred fifty-three patients (group 1) with metastasized NET who underwent PRRNT were examined. Out of these, 185 patients received (177)Lu-DOTATATE, 9 were treated with (177)Lu-DOTANOC, and 59 with (177)Lu-DOTATOC. Additionally, 25 patients receiving, in consecutive PRRNT cycles, DOTATATE followed by DOTATOC (group 2) and 3 patients receiving DOTATATE and DOTANOC (group 3) were analyzed. Dosimetric calculations (according to MIRD scheme) were performed using OLINDA software. In group 1, DOTATOC exhibited the lowest and DOTANOC the highest uptake and therefore mean absorbed dose in normal organs (whole body, kidney, and spleen). In group 2, there was a significant difference between DOTATATE and DOTATOC concerning kinetics and normal organ doses. (177)Lu-DOTATOC had the lowest uptake/dose delivered to normal organs and highest tumor-to-kidney ratio. There were no significant differences between the three peptides concerning tumor kinetics and mean absorbed tumor dose. The study demonstrates a correlation between high affinity of DOTANOC in vitro and high uptake in normal organs/whole body in vivo, resulting in a higher whole-body dose. DOTATOC exhibited the lowest uptake and dose delivered to normal tissues and the best tumor-to-kidney ratio. Due to large interpatient variability, individual dosimetry should be performed for each therapy cycle.

Experimental half-life determination of 176Lu

International Nuclear Information System (INIS)

Kossert, Karsten; Jörg, Gerhard; Gostomski, Christoph Lierse v.

2013-01-01

The half-life of the naturally occurring long-lived rare earth isotope 176 Lu was determined by a combination of highly sophisticated experimental procedures in order to further improve the reliability and the precision of literature data. The amount of lutetium in the samples was determined by inductively coupled plasma optical emission spectrometry (ICP-OES) using a NIST reference standard. The isotopic ratio N( 176 Lu)/N(Lu) in the samples was measured by means of inductively coupled plasma high resolution mass spectrometry (ICP-HRMS). The activity divided by the mass of Lu was determined by applying liquid scintillation (LS) counting. The LS counting efficiency of the beta/gamma emitter 176 Lu was determined with the CIEMAT/NIST efficiency tracing technique with low uncertainty. The influences of colour quenching and background effects are discussed in this paper. The half-life was found to be 3.640(35)×10 10 y. The result is in good agreement with other evaluations and the relative standard uncertainty of 0.95% is among the lowest of previously published data. - Highlights: • The half-life of 176 Lu was determined by ICP-OES, ICP-HRMS and LSC. • The LSC efficiency was determined with the CIEMAT/NIST method. • The half-life was found to be 3.640(35)×10 10 y

Mälu defragmenteerimine / Ilja Sundelevitsh

Index Scriptorium Estoniae

Sundelevitsh, Ilja

2007-01-01

Viktor Misiano kureeritud projekt "Mälu tagasitulek" Kumu Kunstimuuseumis kuni 29. VII. Dmitri Gutovi projektist, mis koosneb videotest "Sula" ja "Kajakad" ning kolmest maalist, Valentin Arhipovi projektist "Vassili Grigorjevitsh Arhipovi looming aastail 1962-2006", Juri Leidermani heliinstallatsioonist "Isa jutustus", Jevgeni Fiksi projektist, Gljuklja & Tzaplja (Olga Jegorova, Natalja Pershina) installatsioonist "Punased purjed", Igor Shtsherbini tööst "Defragmenteerimine. Stirlitzi mälu" ja Sergei Bratkovi tööst

On the crystal structures of USe2, UTe2, ThOTe, and Er2Se3 - a contribution to the crystal chemistry of rare earth and actinide chalcogenides

International Nuclear Information System (INIS)

Dausch, W.M.

1987-01-01

The dichalcogenides of rare earth metals and actinides were classified into isostructural compounds without considering their composition. The structures of of α-USe 2 , β-USe 2 , UTe 2 , and HoSe 2 as well as of ThOTe, Er 2 Se 3 , and UTe 3 were determined by X-ray diffraction of their crystals. The results demonstrate that α-USe 2 has a SrBr 2 -analog structure and a stoichiometric composition. The atomic parameters derived from powder data of ThOTe and UTe 2 could be confirmed by X-ray analysis of the crystalline compounds. ThOTe crystallizes into a PbFCl-analog structure. The order of atoms in UTe 2 is similar to that of the ZrSe 3 type. The crystals of ErSe 3 , UTe 3 , HoSe 2 , and β-USe 2 were investigated only by camera methods. As in the case of Er 2 Se 3 or UTe 3 twin formation could be observed in β-USe 3 . (orig./RB) [de

First evidence for triaxial superdeformation in sup 1 sup 6 sup 1 Lu and sup 1 sup 6 sup 2 Lu

CERN Document Server

Bringel, P; Domscheit, J; Neusser, A; Schoenwasser, G; Singh, A K; Amro, H; Axiotis, M; Kröll, T; Napoli, D R; Bazzacco, D; Lunardi, S; Ur, C; Bhattacharya, S; Bhowmik, R; Hagemann, G B; Jensen, D R; Pancholi, S C; Petrache, C M

2003-01-01

High-spin states in sup 1 sup 6 sup 1 Lu and sup 1 sup 6 sup 2 Lu have been investigated using the GASP gamma-ray spectrometer array. Excited states in these nuclei have been populated through the sup 1 sup 0 sup 0 Mo( sup 6 sup 5 Cu, xn) reaction at a beam energy of 260 MeV. Four presumably triaxial superdeformed bands, three in sup 1 sup 6 sup 2 Lu and one in sup 1 sup 6 sup 1 Lu, have been observed. This is the first evidence for triaxial superdeformation in the two isotopes. (orig.)

Energy levels of Ho3+ in HoCl63-

International Nuclear Information System (INIS)

Tanner, P.A.

1987-01-01

The 5 S 2 , 5 F 4 , 5 F 2 , 3 K 8 , 5 G 6 , 5 F 1 , 5 G 5 5 I 8 absorption spectra of Cs 2 NaHoCl 6 have been recorded at temperatures down to that of liquid helium and new assignments are made for the 5 S 2 , 5 F 4 , 3 K 8 and 5 G 5 terms of HoCl 6 3- . The 5 F 3 → 5 I 8 , 5 F 4 , 5 S 2 → 5 I 7 , 5 I 8 and 5 F 5 → 5 I 7 luminescence transitions of HoCl 6 3- in various elpasolite lattices are reported and assigned, together with luminescence decay measurements. Including the previously reported data, these results enable 57 of the first 60 crystal-field levels of HoCl 6 3- , comprising 14 Lsub(j) terms, to be firmly assigned and tentative assignments are made for the remaining three levels. The agreement between the calculated and observed crystal-field splittings is reasonable. (author)

Synthesis, crystal structure and electrical properties of A-site cation ordered BaErMn2O5 and BaErMn2O6

International Nuclear Information System (INIS)

Świerczek, Konrad; Klimkowicz, Alicja; Zheng, Kun; Dabrowski, Bogdan

2013-01-01

In this paper, we report on a synthesis procedure, structural and electrical properties of BaErMn 2 O 5 and BaErMn 2 O 6 , A-site double perovskites having layered arrangement of Ba and Er cations. These materials belong to a family of BaLnMn 2 O 5+δ oxides, which up to now were successfully synthesized for Ln=Y and La–Ho lanthanides. Up to our knowledge, this is the first report on the successful synthesis of BaErMn 2 O 5 and BaErMn 2 O 6 , yielding>95 wt% of the considered compounds. Structural characterization of the materials is given at room temperature, together with in situ XRD studies, performed during oxidation of BaErMn 2 O 5 in air, at elevated temperatures up to 500 °C. A complex structural behavior was observed, with oxidation process of BaErMn 2 O 5 occurring at around 300 °C. The oxidized BaErMn 2 O 6 shows a structural phase transition at about 225 °C. Results of structural studies are supported by thermogravimetric measurements of the oxidation process, performed in air, as well as reduction process, preformed in 5 vol% of H 2 in Ar. Additionally, isothermal oxidation/reduction cycles were measured at 500 °C, showing interesting properties of BaErMn 2 O 5+δ , from a point of view of oxygen storage technology. Electrical conductivity of BaErMn 2 O 5 is of the order of 10 −4 S cm −1 at room temperature and shows activated character on temperature with activation energy E a =0.30(1) eV. Positive sign of Seebeck coefficient for this material indicates holes as dominant charge carriers. Oxidized BaErMn 2 O 6 possesses much higher electrical conductivity, almost 0.2 S cm −1 at room temperature. Additional, about 10-fold increase of electrical conductivity, occurring in the vicinity of 225 °C for this material, can be associated with phase transition from charge/orbital-ordered insulator COI(CE) to paramagnetic metal PM phase. The highest conductivity for BaErMn 2 O 6 was measured near 500 °C and is almost equal to 40 S cm −1 , while

High spin K isomeric target of {sup 177m}Lu

Energy Technology Data Exchange (ETDEWEB)

Roig, O. E-mail: olivier.roig@cea.fr; Belier, G.; Daugas, J.-M.; Delbourgo, P.; Maunoury, L.; Meot, V.; Morichon, E.; Sauvestre, J.-E.; Aupiais, J.; Boulin, Y.; Fioni, G.; Letourneau, A.; Marie, F.; Ridikas, D

2004-03-21

The techniques used to produce a {sup 177m}Lu (J{sup {pi}}=23/2{sup -},T{sub 1/2}=160.4 days) target are described in this paper. Firstly, an isotopic separation of an enriched lutetium sample was used to reach a purity of {sup 176}Lu close to 99.993%. Afterwards, the high neutron flux of the Grenoble Institut Laue-Langevin reactor was used to produce the {sup 177m}Lu isomer by the {sup 176}Lu(n,{gamma}) reaction. Finally, a chemical separation was performed to extract 10{sup 13} nuclei of {sup 177m}Lu. Thanks to this experiment, we have been able to estimate the destruction cross-section of the {sup 177m}Lu.

Neutron capture reactions on Lu isotopes at DANCE

CERN Document Server

Roig, O

2010-01-01

The DANCE (Detector for Advanced Neutron Capture Experiments) array located at the Los Alamos national laboratory has been used to obtain the neutron capture cross sections for 175Lu and 176Lu with neutron energies from thermal up to 100 keV. Both isotopes are of current interest for the nucleosynthesis s-process in astrophysics and for applications as in reactor physics or in nuclear medicine. Three targets were used to perform these measurements. One was natLu foil and the other two were isotope-enriched targets of 175Lu and 176Lu. The cross sections are obtained for now through a precise neutron flux determination and a normalization at the thermal neutron cross section value. A comparison with the recent experimental data and the evaluated data of ENDF/B-VII.0 will be presented. In addition, resonances parameters and spin assignments for some resonances will be featured.

Electronic and magnetic properties of R0.5A0.5MnO3 compounds (R=Gd, Dy, Ho, Er; A=Sr, Ca)

International Nuclear Information System (INIS)

Terai, T.; Sasaki, T.; Kakeshita, T.; Fukuda, T.; Saburi, T.; Kitagawa, H.; Kindo, K.; Honda, M.

2000-01-01

Electronic and magnetic properties of the perovskitelike compounds of R 0.5 A 0.5 MnO 3 (R=Gd, Dy, Ho, Er; A=Sr, Ca) have been studied by measuring lattice parameter, electrical resistivity, magnetic susceptibility, and magnetization. All the Sr-doped compounds show a transition from a paramagnetic insulator to a spin-glass-like insulator at T g , even though the manganite La 0.5 Ca 0.5 MnO 3 , with nearly the same tolerance factor t, have been shown by others, to have different transitions. On the other hand, all the Ca-doped compounds show a charge-ordering transition at T CO and show a transition from a paramagnetic insulator to a canted antiferromagnetic insulator and/or a spin-glass-like insulator at T CA below T CO . These transition temperatures decrease with decreasing t. In the compound of Gd 0.5 Ca 0.5 MnO 3 , the collapse of the charge ordering has been observed under a pulsed high magnetic field of 45 T at 4.2 K. On the other hand, in the compound of Gd 0.5 Sr 0.5 MnO 3 , the magnetization process depends on the strength of magnetic field. These electronic and magnetic properties depend not only on the tolerance factor but also the variance (second moment) of the A-site ion radii distribution

Computational modelling of Er(3+): Garnet laser materials

Science.gov (United States)

Spangler, Lee H.

1994-01-01

The Er(3+) ion has attracted a lot of interest for four reasons: (1) Its (4)I(sub 13/2) yields (4)I(sub 15/2) transition lases in the eyesafe region near 1.5 micron; (2) the (4)I(sub 13/2) transition lases near 2.8 micron, an important wavelength for surgical purposes; (3) it displays surprisingly efficient upconversion with lasing observed at 1.7, 1.2, 0.85, 0.56, 0.55, and 0.47 micron following 1.5 micron pumping; and (4) it has absorption bands at 0.96 and 0.81 micron and thus can be diode pumped. However, properties desirable for upconversion reduce the efficiency of 1.5 and 3 micron laser operation and vice versa. Since all of the processes are influenced by the host via the crystal field induced stark splittings in the Er levels, this project undertook modelling of the host influence on the Er lasinng behavior. While growth and measurement of all ten Er(3+) doped garnets is the surest way of identifying hosts which maximize upconversion (or conversly, 1.5 and 3 micron performance), it is also expensive - costing approximately $10,000/material or approximately $100,000 for the materials computationally investigated here. The calculations were performed using a quantum mechanical point charge model developed by Clyde Morrison at Harry Diamond Laboratories. The programs were used to fit the Er:YAG experimental energy levels so that the crystal field parameters, B(sub nm) could be extracted. From these radial factors, rho (sub n) were determined for Er(3+) in garnets. These, in combination with crystal field components, Anm, available from X-ray data, were used to predict energy levels for Er in the other nine garnet hosts. The levels in Er:YAG were fit with an rms error of 12.2/cm over a 22,000/cm range. Predicted levels for two other garnets for which literature values were available had rms errors of less than 17/cm , showing the calculations to be reliable. Based on resonances between pairs of calculated stark levels, the model predicts GSGG as the best host

Nuclear Data Sheets for A=158

Energy Technology Data Exchange (ETDEWEB)

Nica, N. [Cyclotron Institute, Texas A& M University, College Station, TX 77843-3366 (United States); On leave from the National Institute for Physics and Nuclear Engineering “Horia Hulubei”, Bucharest (Romania); Under Subcontract No. 100586 with National Nuclear Data Center, Brookhaven National Laboratory, Upton, NY 11973 (United States)

2017-03-15

The experimental results published before February 2017 from the various reaction and decay studies leading to nuclides {sup 158}Nd, {sup 158}Pm, {sup 158}Sm, {sup 158}Eu, {sup 158}Gd, {sup 158}Tb, {sup 158}Dy, {sup 158}Ho, {sup 158}Er, {sup 158}Tm, {sup 158}Yb, {sup 158}Lu, {sup 158}Hf, {sup 158}Ta, {sup 158}W in the A=158 mass chain have been reviewed. These data are summarized and presented, together with adopted level schemes and properties. Large sections of the mass chain are almost identical to the ones in the previous 2004He05 NDS publication by R.G. Helmer.

X-ray fluorescence analysis of thulium oxide/oxalate for rare earth impurities

International Nuclear Information System (INIS)

Chandola, L.C.; Khanna, P.P.

1986-01-01

An X-ray fluorescence spectrometric method for the analysis of thulium oxide is described. For the analysis, the sample in oxalate form is mixed with boric acid binding material and pressed into a pellet over a supporting pellet of boric acid. A wavelength dispersive Philips PW 1220 X-ray fluorescence spectrometer is used for the experiments; the minimum determination limits are 0.002per cent for Ho, Lu and Y, 0.005per cent for Dy and Er and 0.01per cent for Yb. Calculations for theoretical minimum detection limits and percent standard deviation at each concentration of the standard are carried out. (author)

Histological and Thermometric Examination of Soft Tissue De-Epithelialization Using Digitally Controlled Er:YAG Laser Handpiece: An Ex Vivo Study.

Science.gov (United States)

Grzech-Leśniak, Kinga; Matys, Jacek; Jurczyszyn, Kamil; Ziółkowski, Piotr; Dominiak, Marzena; Brugnera Junior, Aldo; Romeo, Umberto

2018-06-01

The purpose of this study was histological and thermometric examination of soft tissue de-epithelialization using digitally controlled laser handpiece (DCLH) - X-Runner. Commonly used techniques for de-epithelialization include scalpel, abrasion with diamond bur, or a combination of the two. Despite being simple, inexpensive and effective, these techniques are invasive and may produce unwanted side effects. It is important to look for alternative techniques using novel tools, which are minimally invasive and effective. 114 porcine samples sized 6 × 6 mm were collected from the attached gingiva (AG) of the alveolar process of the mandible using 15C scalpel blade. The samples were irradiated by means of Er:YAG laser (LightWalker, Fotona, Slovenia), using X-Runner and HO 2 handpieces at different parameters; 80, 100, and 140 mJ/20 Hz in time of 6 or 16 sec, respectively. The temperature was measured with a K-type thermocouple. For the histopathological analysis of efficiency of epithelium removal and thermal injury, 3 random samples were de-epithelialized with an HO 2 handpiece, and 9 random samples with an X-Runner handpiece with different parameters. For the samples irradiated with DCLH, we have used three different settings, which resulted in removing 1 to 3 layers of the soft tissue. The efficiency of epithelium removal and the rise of temperature were analyzed. DCLH has induced significantly lower temperature increase compared with HO 2 at each energy to frequency ratio. The histological examination revealed total epithelium removal when HO 2 handpiece was used at 100 and 140 mJ/20 Hz and when DCLH was used for two- and threefold lasing at 80, 100, and 140 mJ/20 Hz. Er:YAG laser with DCLH handpiece may be an efficient tool in epithelium removal without excessive thermal damage.

Comparison of tumour and whole body absorbed doses of 177-Lu-DOTA-TATE and Lu-177-DOTA-NOC treatment in the same patient group

International Nuclear Information System (INIS)

Yeyin, N.; Kabasakal, L.; Akyel, R.; Demir, M.; Kanmaz, B.; Ocak, M.; Toklu, T.; Selcuk, N.

2015-01-01

Full text of publication follows. Peptide Receptor Radionuclide Therapy (PRRT) with Lu-177 labelled peptides in patients with neuroendocrine tumours (NETs) aroused great interest. An estimation of actual radiation doses to tumours is very important for therapy planning. There are several radiolabelled peptides, which can be used for PRRT with different biological behaviour. Aim: the aim of the study was to compare the tumour and normal organ absorbed doses in patients who have received Lu-177-DOTA-TATE and Lu-177 DOTA-NOC. Materials and methods: study was composed of 20 patients (M/F: 10/10, mean age: 51.5 ± 14.9) with histologically proven inoperable NETs. All patients received Lu-177-DOTA-NOC treatment 6 to 12 weeks after last Lu-177-DOTA-TATE treatment. Dosimetric calculations were performed using MIRD scheme and lesion doses were calculated using post therapy whole body images obtained at 4, 20, 44, and 68 hours after injection. Tumour volumes were determined from CT images. Thirteen blood samples beginning from time zero to 4 days after injection were obtained for bone marrow and whole body dosimetry. Results: There were 53 lesions in Lu-177-DOTA-TATE post-therapy whole body images and 49 lesions in Lu-177 DOTA-NOC post therapy images. Lesions were selected according to lesion delineation and superimposed lesions were excluded. Mean lesion absorbed dose is calculated to be 47.4 ± 53.4 and 42.9 ± 52.8 Gy per 370 MBq for Lu-177-DOTA-TATE and DOTA-NOC respectively (p>0.5). There were significantly higher absorbed doses for kidney and bone marrow after Lu-177-DOTA-NOC treatment as compared to Lu-177-DOTA-TATE treatment, which were 6.9 ± 2.7 vs 3.9 ± 1.7 (p<0.05) and 0.12 ± 0.0 vs 0.10 ± 0.0 (p<0.05) Gy, respectively. There was not any difference in plasma elimination times between two tracers. On the other hand the whole body absorbed dose was significantly higher after Lu-177-DOTA-NOC treatment, which was 0.24 ± 0.07 vs 0.20 ± 0.06 Gy (p<0

Advances on LuGre friction model

OpenAIRE

Fuad, Mohammad; Ikhouane, Fayçal

2013-01-01

LuGre friction model is an ordinary differential equation that is widely used in describing the friction phenomenon for mechanical systems. The importance of this model comes from the fact that it captures most of the friction behavior that has been observed including hysteresis. In this paper, we study some aspects related to the hysteresis behavior induced by the LuGre friction model.

Linear thermal expansivity and Cp measurements for LuHx and LuDx (x=0.005 and 0.053) single crystals

International Nuclear Information System (INIS)

Swenson, C.A.

1996-01-01

Linear thermal expansivity (α) measurements from 1 to 300 K and heat capacity (C p ) measurements from 1 to 110 K are reported for single crystals of the α-Lu hexagonal alloys LuH x and LuD x (x=0.005 and 0.053). The C p data confirm and extend to 110 K earlier 1 to 20 K measurements on LuH x alloys, and show that isotope effects, if any, are small. The small x dependences of the C p close-quote s above 8 K can be associated with small increases in the Debye temperature Θ 0 . This latter interpretation, which is consistent with ultrasonic and other results for these alloys, is valid only if C p is expressed as mJ/gmolK (essentially, per mole of Lu ions). Results are in agreement with the previous conclusion from more extensive polycrystalline LuH x data that the shape of the low-temperature C p vs T relation for x≤0.015 is qualitatively different from that for x≥0.032. The linear thermal expansivities of the c-axis alloys, even for x=0.005, are significantly smaller (by from 3% to 20%) than those for the pure crystals, with large isotope effects and a large, nonlinear x dependence for the low-temperature expansivity data. Other types of data have shown a feature near 170 K which is associated with the completion of pairing of the hydrogens along the c axis in next-nearest-neighbor tetrahedral sites. A distinct (approximately 15 K wide) change in α which is observed near this temperature for each alloy, except for a-axis LuD 0.005 , provides the most direct evidence of such a transition. The temperature of the c-axis discontinuity is slightly isotope and x dependent, and scales approximately with x [+24% on warming for LuH(or D) 0.053 ]. (Abstract Truncated)

The oxonitridoborate Eu{sub 5}(BO{sub 2.51(7)}N{sub 0.49(7)}){sub 4} and the mixed-valent borates Sr{sub 3}Ln{sub 2}(BO{sub 3}){sub 4} (Ln = Ho, Er)

Energy Technology Data Exchange (ETDEWEB)

Hoeppe, Henning A.; Kazmierczak, Karolina; Grumbt, Christine; Schindler, Lisa [Institut fuer Physik, Universitaet Augsburg (Germany); Schellenberg, Inga; Poettgen, Rainer [Westfaelische Wilhelms-Universitaet Muenster, Institut fuer Anorganische und Analytische Chemie (Germany)

2013-11-04

The crystal structures of the mixed borates Sr{sub 3}Er{sub 2}(BO{sub 3}){sub 4} [Pnma, no. 62, Z = 4, a = 738.08(2), b = 1588.94(4), c = 867.81(2) pm, 683 reflections, 70 parameters, R1 = 0.037, wR2 = 0.077] and Sr{sub 3}Ho{sub 2}(BO{sub 3}){sub 4} [Pnma, no. 62, Z = 4, a = 738.45(7), b = 1591.55(12), c = 871.03(9) pm, 691 reflections, 59 parameters, R1 = 0.069, wR2 = 0.098] and europium oxonitridoborate Eu{sub 5}(BO{sub 2.51(7)}N{sub 0.49(7)}){sub 4} [Pnma, no. 62, Z = 12, a = 2232.2(5), b = 1603.1(3), c = 879.59(18) pm, 2880 reflections, 313 parameters, R1 = 0.027, wR2 = 0.059] were solved from single-crystal X-ray diffraction data. Eu{sub 5}(BO{sub 2.51(7)}N{sub 0.49(7)}){sub 4} adopts a threefold superstructure of the structure of Sr{sub 3}Ln{sub 2}(BO{sub 3}){sub 4} (Ln = Ho, Er). In both structure types, the different cations are situated on common sites with a pronounced preferential occupation but no complete ordering. These conclusions are based on the crystal structure refinement, {sup 151}Eu Moessbauer spectroscopy and MAPLE (Madelung part of lattice energy) calculations. The proposed Eu{sub 5}(BO{sub 3}){sub 4} contains nitrogen and has a formula Eu{sub 5}(BO{sub 2.51(7)}N{sub 0.49(7)}){sub 4} as confirmed by {sup 151}Eu Moessbauer spectroscopy. The optical reflectance spectrum of Eu{sub 5}(BO{sub 2.51(7)}N{sub 0.49(7)}){sub 4} is in accordance with the yellow colour of the compound. (Copyright copyright 2013 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

Complexes of Y, La, and lanthanides with m-aminobenzoic acid

International Nuclear Information System (INIS)

Rzaczynska, Z.; Brzyska, W.

1989-01-01

m-Aminobenzoates of Y, La and lanthanides prepared in the reaction of the hydroxides of metal with m-aminobenzoic acid in solution have the general formula Ln(m-C 6 H 4 NH 2 COO) 3 .nH 2 O where n = 4 for Ho, Tm, n = 5 for Y, Sm, Dy, Er, Lu, and n = 6 for La, Nd, Eu, Gd, Tb, Yb. The water molecules in the hydrated compounds are in the outer coordination sphere. On heating in air at 350-410K dehydration occurs and anhydrous m-aminobenzoates Ln(m-C 6 H 4 NH 2 COO) 3 are formed. On the basis of the IR spectra it was found that the metal in hydrated m-aminobenzoate of lanthanides is simultaneously coordinated through amino- and carboxyl groups whereas in anhydrous m-aminobenzoates of lanthanides only trough the bidentate carboxyl group. From X-ray analysis it was stated that the hydrated m-aminobenzoates of lanthanides are isostructural in the whole range Y, La-Lu. (Author)

Production of 177Lu for targeted radionuclide therapy: Available options

International Nuclear Information System (INIS)

Dah, Ashutosh; Pillai, Maroor Raghavan Ambikalmajan; Knapp, Furn F. Jr.

2015-01-01

This review provides a comprehensive summary of the production of 177 Lu to meet expected future research and clinical demands. Availability of options represents the cornerstone for sustainable growth for the routine production of adequate activity levels of 177 Lu having the required quality for preparation of a variety of 177 Lu-labeled radiopharmaceuticals. The tremendous prospects associated with production of 177 Lu for use in targeted radionuclide therapy (TRT) dictate that a holistic consideration should evaluate all governing factors that determine its success. While both “direct” and “indirect” reactor production routes offer the possibility for sustainable 177 Lu availability, there are several issues and challenges that must be considered to realize the full potential of these production strategies. This article presents a mini review on the latest developments, current status, key challenges and possibilities for the near future. A broad understanding and discussion of the issues associated with 177 Lu production and processing approaches would not only ensure sustained growth and future expansion for the availability and use of 177 Lu-labeled radiopharmaceuticals, but also help future developments

Dosimetric Studies in Normal Mice of 177Lu-DOTA-SP and 177Lu-DOTA-His2-MG

International Nuclear Information System (INIS)

Puerta Yepes, N.; Rojo, A.M.; Lopez Bularte, A.C.; Nevares, N.; Zapata, M.; Perez, J.H.; Crudo, J.

2010-01-01

DOTA-Substance-P (SP) and DOTA-minigastrin (His2-MG) labeled with 177 Lu could be used in peptide receptor radionuclide therapy (PRRT) for treatment of various tumour species. Biodistribution studies of both radiopharmaceuticals in normal mice were performed at different times. Absorbed doses in mouse organs were estimated and extrapolated to humans. Dosimetric calculations showed that kidneys received the highest dose, for both radiopharmaceuticals. The Maximum Tolerated Activity (MTA) of 177 Lu-DOTA-SP that can be administered without kidney toxicity are 414 and 422 MBq/kg for the standard adult man and woman, respectively. In the same way, the MTA of 177 Lu-DOTA-His2-MG are 488 and 518 MBq/kg for the standard adult man and woman, respectively. (authors)

Heme oxygenase-1 comes back to endoplasmic reticulum

Energy Technology Data Exchange (ETDEWEB)

Kim, Hong Pyo [School of Biological Sciences, Ulsan University (Korea, Republic of); Pae, Hyun-Ock [Department of Immunology, Wonkwang University School of Medicine (Korea, Republic of); Back, Sung Hun; Chung, Su Wol [School of Biological Sciences, Ulsan University (Korea, Republic of); Woo, Je Moon [Department of Opthalmology, Ulasn University Hospital (Korea, Republic of); Son, Yong [Department of Anesthesiology and Pain Medicine, Wonkwang University School of Medicine (Korea, Republic of); Chung, Hun-Taeg, E-mail: chung@ulsan.ac.kr [School of Biological Sciences, Ulsan University (Korea, Republic of)

2011-01-07

Research highlights: {yields} Although multiple compartmentalization of HO-1 has been documented, the functional implication of this enzyme at these subcellular organelles is only partially elucidated. {yields} HO-1 expression at ER is induced by a diverse set of conditions that cause ER stressors. {yields} CO may induce HO-1 expression in human ECs by activating Nrf2 through PERK phosphorylation in a positive-feedback manner. {yields} ER-residing HO-1 and its cytoprotective activity against ER stress is discussed. -- Abstract: Originally identified as a rate-limiting enzyme for heme catabolism, heme oxygenase-1 (HO-1) has expanded its roles in anti-inflammation, anti-apoptosis and anti-proliferation for the last decade. Regulation of protein activity by location is well appreciated. Even though multiple compartmentalization of HO-1 has been documented, the functional implication of this enzyme at these subcellular organelles is only partially elucidated. In this review we discuss the endoplasmic reticulum (ER)-residing HO-1 and its cytoprotective activity against ER stress.

Comparative study of optical and scintillation properties of YVO4, (Lu0.5Y0.5)VO4, and LuVO4 single crystals

International Nuclear Information System (INIS)

Fujimoto, Yutaka; Yanagida, Takayuki; Yokota, Yuui; Chani, Valery; Kochurikhin, Vladimir V.; Yoshikawa, Akira

2011-01-01

Optical and scintillation properties of YVO 4 , (Lu 0.5 Y 0.5 )VO 4 , and LuVO 4 single crystals grown by the Czochralski (CZ) method with RF heating system are compared. All vanadate crystals show high transmittance (∼80%) in the 400-900 nm wavelength range. In both photo- and radio-luminescence spectra, intense peak around 400-500 nm, which was ascribed to the transition from triplet state of VO 4 3- , was clearly observed. The main decay time component was about 38 μs (YVO 4 ), 18 μs ((Lu 0.5 Y 0.5 )VO 4 ), and 17 μs (LuVO 4 ) under 340 nm excitation. The scintillation light yields of YVO 4 , (Lu 0.5 Y 0.5 )VO 4 , and LuVO 4 crystals (obtained from the 137 Cs excited pulse height spectra) were evaluated to be about 11,200, 10,700, and 10,300 ph/MeV, respectively.

Výložník kombinovaného skládkového stroje

OpenAIRE

Štursa, Martin

2013-01-01

Tato diplomová práce se zabývá konstrukcí částí kombinovaného skládkového stroje určeného pro obsluhu skládky hnědého uhlí u uhelné elektrárny. Nejprve jsou nadefinovány základní parametry stroje a silové účinky zatěžující stroj během provozu. Práce dále obsahuje návrh ocelové konstrukce kolesového výložníku, kolesa, korečků, pohonu kolesa, hřídele, ložisek a dalších částí kolesového výložníku. Tyto součásti jsou ověřeny analytickými nebo konečnoprvkovými výpočty. This master’s thesis deal...

Exploiting fine-grain parallelism in recursive LU factorization

KAUST Repository

Dongarra, Jack

2012-01-01

The LU factorization is an important numerical algorithm for solving system of linear equations. This paper proposes a novel approach for computing the LU factorization in parallel on multicore architectures. It improves the overall performance and also achieves the numerical quality of the standard LU factorization with partial pivoting. While the update of the trailing submatrix is computationally intensive and highly parallel, the inherently problematic portion of the LU factorization is the panel factorization due to its memory-bound characteristic and the atomicity of selecting the appropriate pivots. We remedy this in our new approach to LU factorization of (narrow and tall) panel submatrices. We use a parallel fine-grained recursive formulation of the factorization. It is based on conflict-free partitioning of the data and lock-less synchronization mechanisms. Our implementation lets the overall computation naturally flow with limited contention. Our recursive panel factorization provides the necessary performance increase for the inherently problematic portion of the LU factorization of square matrices. A large panel width results in larger Amdahl\\'s fraction as our experiments have revealed which is consistent with related efforts. The performance results of our implementation reveal superlinear speedup and far exceed what can be achieved with equivalent MKL and/or LAPACK routines. © 2012 The authors and IOS Press. All rights reserved.

Additional lesions detected in therapeutic scans with 177Lu-DOTATATE reflect higher affinity of 177Lu-DOTATATE for somatostatin receptors.

Science.gov (United States)

Mirzaei, Siroos; Bastati, Brigitte; Lipp, Rainer W; Knoll, Peter; Zojer, Niklas; Ludwig, Heinz

2011-01-01

Peptide receptor-targeted radionuclide therapy (PRRT) of somatostatin receptor (SR)-expressing neuroendocrine tumors (NETs) has become an established therapeutic option in patients with advanced NETs. The aim of this study was to compare the lesion detection rate of (99m)Tc-EDDA/HYNIC-TOC, a newly developed tracer for NET imaging, with (177)Lu-DOTATATE used for PRRT. 8 patients (4 women, 4 men, age range 46-76 years) with histologically proven NETs, who showed high SR loads by (99m)Tc-EDDA/HYNIC-TOC scintigraphy, were treated with (177)Lu-DOTATATE. After treatment, all patients were subjected to whole-body scintigraphy with additional low-dose single-photon emission computed tomography (SPECT-CT) of the chest and abdomen. All patients demonstrated (177)Lu-DOTATATE accumulation in all lesions previously detected by (99m)Tc- EDDA/HYNIC-TOC scintigraphy. Three patients showed additional lesions in the liver and lungs. SPECT-CT after (177)Lu-DOTATATE therapy may be helpful in detecting additional lesions not seen using (99m)Tc-EDDA/HYNIC-TOC. This could reflect the broader affinity of (177)Lu-DOTATATE for SRs compared with (99m)Tc-EDDA/HYNIC-TOC. Copyright © 2011 S. Karger AG, Basel.

Hydrothermal synthesis, characterization and up/down-conversion luminescence of barium rare earth fluoride nanocrystals

International Nuclear Information System (INIS)

Jia, Li-Ping; Zhang, Qiang; Yan, Bing

2014-01-01

Graphical abstract: Lanthanide ions doped bare earth rare earth fluoride nanocrystals are synthesized by hydrothermal technology and characterized. The down/up-conversion luminescence of them are discussed. - Highlights: • Mixed hydrothermal system H 2 O–OA (EDA)–O-A(LO-A) is used for synthesis. • Barium rare earth fluoride nanocrystals are synthesized comprehensively. • Luminescence for down-conversion and up-conversion are obtained for these systems. - Abstract: Mixed hydrothermal system H 2 O–OA (EDA)–O-A(LO-A) is developed to synthesize barium rare earth fluorides nanocrystals (OA = oleylamine, EDA = ethylenediamine, O-A = oleic acid and LO-A = linoleic acid). They are presented as BaREF 5 (RE = Ce, Pr, Nd, Eu, Gd, Tb, Dy, Y, Tm, Lu) and Ba 2 REF 7 (RE = La, Sm, Ho, Er, Yb). The influence of reaction parameters (rare earth species, hydrothermal system and temperature) is checked on the phase and shape evolution of the fluoride nanocrystals. It is found that reaction time and temperature of these nanocrystals using EDA (180 °C, 6 h) is lower than those of them using OA (220 °C, 10 h). The photoluminescence properties of these fluorides activated by some rare earth ions (Nd 3+ , Eu 3+ , Tb 3+ ) are studied, and especially up-conversion luminescence of the four fluoride nanocrystal systems (Ba 2 LaF 7 :Yb, Tm(Er), Ba 2 REF 7 :Yb, Tm(Er) (RE = Gd, Y, Lu)) is observed

Vodní malakofauna dolního toku Lužnice se zaměřením na stav populace velevruba tupého (Unio crassus Aquatic molluscan fauna of the lower part of the Lužnice River (South Bohemia, Czech Republic with focus on the population of Unio crassus

Directory of Open Access Journals (Sweden)

Luboš Beran

2012-02-01

Full Text Available This paper presents results of a malacological survey of the Lužnice River in ca 70 km long stretch between the inflow of its main tributary the Nežárka River in Veselí nad Lužnicí and its confluence with the Vltava River in Southern Bohemia (Czech Republic. Thirty-one species of aquatic molluscs (19 gastropods, 12 bivalves representing 40% of freshwater molluscan fauna of the Czech Republic were found at 15 sites. Differences of molluscan assemblages upstream and downstream of Tábor town were probably caused by different characters of the watercourse. The occurrence of rare bivalve Pseudanodonta complanata was confirmed. On the other hand, two non-native species Physella acuta and Sinanodonta woodiana were recorded. The research was preferentially focused on the population of the endangered bivalve Unio crassus. Its occurrence was confirmed at 8 from 15 sites under study but altogether only 31 individuals were found. Less than four specimens were found at particular sites but one.

Encapsulation of a radiolabeled cluster inside a fullerene cage, (177)Lu(x)Lu((3-x))N@C(80): an interleukin-13-conjugated radiolabeled metallofullerene platform.

Science.gov (United States)

Shultz, Michael D; Duchamp, James C; Wilson, John D; Shu, Chun-Ying; Ge, Jiechao; Zhang, Jianyuan; Gibson, Harry W; Fillmore, Helen L; Hirsch, Jerry I; Dorn, Harry C; Fatouros, Panos P

2010-04-14

In this communication, we describe the successful encapsulation of (177)Lu into the endohedral metallofullerene (177)Lu(x)Lu(3-x)N@C(80) (x = 1-3) starting with (177)LuCl(3) in a modified quartz Kraschmer-Huffman electric generator. We demonstrate that the (177)Lu (beta-emitter) in this fullerene cage is not significantly released for a period of up to at least one-half-life (6.7 days). We also demonstrate that this agent can be conjugated with an interleukin-13 peptide that is designed to target an overexpressed receptor in glioblastoma multiforme tumors. This nanoparticle delivery platform provides flexibility for a wide range of radiotherapeutic and radiodiagnostic multimodal applications.

LU factorization for accelerator-based systems

KAUST Repository

Agullo, Emmanuel

2011-12-01

Multicore architectures enhanced with multiple GPUs are likely to become mainstream High Performance Computing (HPC) platforms in a near future. In this paper, we present the design and implementation of an LU factorization using tile algorithm that can fully exploit the potential of such platforms in spite of their complexity. We use a methodology derived from previous work on Cholesky and QR factorizations. Our contributions essentially consist of providing new CPU/GPU hybrid LU kernels, studying the impact on performance of the looking variants as well as the storage layout in presence of pivoting, tuning the kernels for two different machines composed of multiple recent NVIDIA Tesla S1070 (four GPUs total) and Fermi-based S2050 GPUs (three GPUs total), respectively. The hybrid tile LU asymptotically achieves 1 Tflop/s in single precision on both hardwares. The performance in double precision arithmetic reaches 500 Gflop/s on the Fermi-based system, twice faster than the old GPU generation of Tesla S1070. We also discuss the impact of the number of tiles on the numerical stability. We show that the numerical results of the tile LU factorization will be accurate enough for most applications as long as the computations are performed in double precision arithmetic. © 2011 IEEE.

In-beam spectroscopy study of the proton emitter 151Lu

International Nuclear Information System (INIS)

Yu, C.; Rykaczewski, K.; Toth, K.S.; Akovali, Y.; Baktash, C.; Galindo-Uribarri, A.; Gross, C.J.; Paul, S.D.; Radford, D.C.; Batchelder, J.C.; Gross, C.J.; Bingham, C.R.; Grzywacz, R.; Kim, S.H.; Weintraub, W.; Ginter, T.N.; Grzywacz, R.; Rykaczewski, K.; Karny, M.; MacDonald, B.D.; Szerypo, J.

1998-01-01

Gamma rays decaying from the excited states of the proton-unbound 151 Lu were observed for the first time in an experiment using the 96 Ru( 58 Ni,p2n) 151 Lu reaction. These γ rays were identified by correlating prompt γ radiations at the target position with 151 Lu proton radioactivities at the focal plane of a recoil mass separator. Systematic data on N=80 isotones suggest a possible isomeric level at high spin in 151 Lu. Our measurement was unable to observe such an isomer, but provided an upper limit on its half-life. The observed γ rays in 151 Lu can be interpreted in terms of two possible level structures. copyright 1998 The American Physical Society

Biferroic LuCrO3: Structural characterization, magnetic and dielectric properties

International Nuclear Information System (INIS)

Durán, A.; Meza F, C.; Morán, E.; Alario-Franco, M.A.; Ostos, C.

2014-01-01

Multiferroic LuCrO 3 perovskite-type structure (Pbnm) obtained via auto-ignition synthesis was characterized by a combination of X-ray diffraction (XRD) and thermogravimetric (TG) techniques, and through magnetization and permittivity measurements. Results showed that amorphous combustion powders were fully transformed to orthorhombic LuCrO 3 structure at 1200 K after the first LuCrO 4 crystallization at 700 K. The magnetic response displays thermal irreversibility between zero-field-cooling and field-cooling condition which is due to spin canted AF switching at 116 K. Accordingly, a hysteresis loop in the M(H) data confirms weak ferromagnetism in LuCrO 3 . On the other hand, the permittivity measurement shows a broad peak transition typical of relaxor-type ferroelectrics transition at ∼450 K. Electrical conductivity increases as temperature increases showing an anomaly around the diffuse phase transition. The diffuse phase transition and the formation of the charge carriers are discussed in terms of a local distortion around the Lu Site. - Highlights: • Multiferroic LuCrO 3 was successfully obtained via auto-ignition synthesis. • Amorphous powder is transformed first to LuCrO 4 (700 K) and next to LuCrO 3 (1100 K). • The CrO 6 octahedra are tilted away and rotates from the ideal octahedral shape. • LuCrO 3 exhibits a canted AFM transition (116 K) and a relaxor ferroelectric behavior. • Tilting and rotation of CrO 6 octahedra influenced transport properties on LuCrO 3

Study of quantitative analysis of rare earth elements (Sc, Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu) in soil samples by inductively couple plasma mass spectrometry

International Nuclear Information System (INIS)

Truong Duc Toan; Nguyen Giang; Vo Tran Quang Thai; Do Tam Nhan; Nguyen Le Anh; Nguyen Viet Duc; Luong Thi Tham; Truong Thi Phuong Mai

2015-01-01

Method for the determination of 16 rare earth elements (REEs) in soil samples without separating by inductively coupled plasma mass spectrometry (ICP-MS) has been studied at Dalat Nuclear Research Institute. The optimal conditions for ICP-MS NexION 300X with three modes: Standard, Collision (KED), and Reaction (DRC) have been studied on the Montana II soil reference material. The result analysis shows that: DRC mode only gives good analysis result for Sc, Y, La, Ce, Pr, Nd, Tm, Yb, and Lu; Standard mode exhibits good analysis results for all elements with error from 1.2 - 29.0% and KED mode is the best one with error less than 15%. The concentrations of elements in the soil samples of Cau Dat, Bao Loc, and Da Lat were determined, which concentrations of REEs in soil samples of Cau Dat are higher than that of the other areas in Lam Dong Province. (author)

Motorické projevy laterality u osob středního věku a starších

OpenAIRE

Habartová, Lucie

2008-01-01

Název dielomové eráce: Motorické projevy laterality u osob středního věku a starších. Název v gnglickém jazyce: The Manifestations of Motoric Laterality of Middle-aged People and Elderly. Cíle eráce: Definovat, popsat lateralitu, zjistit stupeň laterality horní končetiny, dolní končetiny a oka. Zjistit vztah laterality horních končetin a očí, horních končetin a dolních končetin. Metoda: Lateralitu budeme zjišťovat na základě dotazníků a motorických testů. Testovaný soubor čítá 50 probandů ve ...

Reaction rate constant of HO2+O3 measured by detecting HO2 from photofragment fluorescence

Science.gov (United States)

Manzanares, E. R.; Suto, Masako; Lee, Long C.; Coffey, Dewitt, Jr.

1986-01-01

A room-temperature discharge-flow system investigation of the rate constant for the reaction 'HO2 + O3 yields OH + 2O2' has detected HO2 through the OH(A-X) fluorescence produced by photodissociative excitation of HO2 at 147 nm. A reaction rate constant of 1.9 + or - 0.3 x 10 to the -15th cu cm/molecule per sec is obtained from first-order decay of HO2 in excess O3; this agrees well with published data.

Mixed Messages from Garnet Lu-Hf and Sm-Nd Geochronology

Science.gov (United States)

Vervoort, J. D.; Wang, D.; Johnson, T. A.

2017-12-01

Garnet geochronology provides important information on the timing and conditions of metamorphism. As a major indicator mineral formed during metamorphism, its direct dating can not only help establish the timing of metamorphism, provide the "t" for P-T-t paths, but also, if the dated garnet can be placed in a textural context, can provide information on the timing of deformational features. With advances in chemistry and mass spectrometry, garnet Lu-Hf and Sm-Nd geochronology has become an important geochronological tool and we can now reliably (if not routinely) date a wide variety of garnet compositions formed under diverse conditions. In the course of dating a variety of lithologies using both Lu-Hf and Sm-Nd isotope systems, however, some intriguing results have emerged. Although there are many examples where the Lu-Hf and Sm-Nd systems give the same date within uncertainty, there are also many cases where these systems yield significantly different dates, and the differences between these dates can be considerable—many 10's of Ma of and even 100's of Ma. For example, in garnet-bearing Mesoproterozoic gneisses from across the Blue Ridge Province in Virginia, both Lu-Hf and Sm-Nd analyses (determined on the same solutions) define narrow time spans, but with the Sm-Nd dates systematically younger (for orthogneisses Lu-Hf dates are 1032 to 1019 Ma whereas Sm-Nd dates are 965 to 949 Ma—a difference of 67 to 80 Ma). There are many other examples of systematically younger Sm-Nd garnet dates in both the literature and with our ongoing research. Potential explanations for these differences include: 1) strong partitioning of Lu into garnet during growth yielding ages weighted toward the beginning of growth; 2) faster Lu diffusion from high Lu regions after garnet formation, potentially leading to isochron rotation and anomalously old Lu-Hf dates; and 3) differences in closure temperatures of the two isotope systems. We will review several examples of divergent Lu

Mälu Instituut uurib inimõiguste rikkumisi

Index Scriptorium Estoniae

2008-01-01

President Toomas Hendrik Ilvese eestvedamisel asutati 20. sajandi teisel poolel Eestis toimunu põhjalikumaks uurimiseks Eesti Mälu Instituut. Ilmunud ka: Eesti Päevaleht (Stockholm) 14. veebr. 2008, lk. 2, pealk.: Mälu Instituut alustas tegevust; Vaba Eesti Sõna 7. veebr. 2008, lk. 12, pealk.: Under the leadership of President Ilves, the Memory Institute was established

First-principles study of rare-earth (RE) cobaltites (RE=Nd,Sm,Gd,Dy,Er,Lu)

Science.gov (United States)

Topsakal, M.; Wentzcovitch, R. M.

2014-12-01

The lanthanide series of the periodic table comprises 15 members ranging from Lanthanum (La) to Lutetium (Lu). Although they are more abundant than silver, and some of them are more abundant than lead, they are known as rare-earth (RE) elements. The "rare" in their name refers to the difficulty of obtaining the pure elements, not to their abundances in nature. They are never found as free metals in the Earth's crust and do not exist as pure minerals. Using first-principles plane-wave calculations, we investigate the structural and electronic properties of rare-earth cobaltites (RECoO3). Structurally consistent Hubbard U treatment was shown to essential for proper description of strongly correlated cobalt-d electrons. We successfully capture the experimentally observed structural trends and give first-principles insights on interesting phenomena related with the cobalt spin state change. It was demonstrated that increase of crystal-field splitting energy between eg-t2g orbitals and shrinking of unoccupied σ*-bonding eg bands are responsible for the increase of onset spin-state transition temperature along the series.

Infra-red laser source using Tm:Ho optical fibre for potential sensor applications

International Nuclear Information System (INIS)

Chen, S Y; Yeo, T L; Leighton, J; Sun, T; Grattan, K T V; Lade, R; Powell, B; Foster-Turner, G; Osborne, M

2007-01-01

In this work, a 1600nm Er fibre laser, which demonstrates a high pumping efficiency, has been used to pump an efficient all-fibre Tm:Ho laser system using a 0.3 m length of optical fibre. A low threshold of 33 mW and a slope efficiency of 0.6% have been achieved with operation at a wavelength of ∼1870 nm. A cross-comparison has been made with the output of a device pumped by a 785 nm laser diode. The focus of the work is better and more compact sources for gas sensing in the near infra red region of the spectrum

Acoustic study of the characteristic temperature of metals

International Nuclear Information System (INIS)

Tekuchev, V.V.; Rygalov, L.N.; Ivanova, I.V.; Barashkov, B.I.

2000-01-01

The calculation of the Debye temperature for 64 metals, including Be, La, Mo, W, Os, Ni, Cd, In, Ta, U, Sc, Cs, Sr, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Dy, Ho, Er, Yb, Lu, Th is carried out. The data on polonium and promethium are obtained for the first time. The calculation is performed with application of ultrasound velocity value at the melting temperature of the given metal. The average derivation of the calculational data on the Debye temperature from the published ones equals 12%. It is noted, that application of the acoustic method for determination of the characteristic temperature makes it possible to solve the wide range of theoretical and applied problems [ru

Electronic, ductile, phase transition and mechanical properties of Lu-monopnictides under high pressures.

Science.gov (United States)

Gupta, Dinesh C; Bhat, Idris Hamid

2013-12-01

The structural, elastic and electronic properties of lutatium-pnictides (LuN, LuP, LuAs, LuSb, and LuBi) were analyzed by using full-potential linearized augmented plane wave within generalized gradient approximation in the stable rock-salt structure (B1 phase) with space group Fm-3m and high-pressure CsCl structure (B2 phase) with space group Pm-3m. Hubbard-U and spin-orbit coupling were included to predict correctly the semiconducting band gap of LuN. Under compression, these materials undergo first-order structural transitions from B1 to B2 phases at 241, 98, 56.82, 25.2 and 32.3 GPa, respectively. The computed elastic properties show that LuBi is ductile by nature. The electronic structure calculations show that LuN is semiconductor at ambient conditions with an indirect band gap of 1.55 eV while other Lu-pnictides are metallic. It was observed that LuN shows metallization at high pressures. The structural properties, viz, equilibrium lattice constant, bulk modulus and its pressure derivative, transition pressure, equation of state, volume collapse, band gap and elastic moduli, show good agreement with available data.

Preparation of 177Lu-DTPA-BIS-BIOTIN and biodistribution evaluation in normal mice

International Nuclear Information System (INIS)

Deng Xinrong; Luo Zhifu; Du Jin

2010-01-01

The labeling method for 177 Lu-DTPA-BIS-BIOTIN was established, and the biodistribution of 177 Lu-DTPA-BIS-BIOTIN in normal mice was carried out as well. Under the optimal experimental condition (DTPA-BIS-BIOTIN 25 μg, pH=4.5 reacting at 80 degree C for 20 min), the labeling yield of 177 Lu-DTPA-BIS-BIOTIN is more than 99.0%. 177 Lu-DTPA-BIS-BIOTIN shows pretty good in vitro stability. The biodistribution of 177 Lu-DTPA-BIS-BIOTIN in normal mice shows a rapid blood clearance. The uptake of 177 Lu-DTPA-BIS-BIOTIN is mainly accumulated in liver, spleen and kidney. 177 Lu-DTPA-BIS-BIOTIN is excreted by kidney. The results provide the basis for further study on 177 Lu-DTPA-BIS-BIOTIN used in pretargeted radioimage and radiotherapy of cancer. (authors)

Production of {sup 177}Lu for targeted radionuclide therapy: Available options

Energy Technology Data Exchange (ETDEWEB)

Dah, Ashutosh [Isotope Production and Applications Division, Bhabha Atomic Research Centre (BARC), Mumbai (India); Pillai, Maroor Raghavan Ambikalmajan [Molecular Group of Companies. Kerala (India); Knapp, Furn F. Jr. [Medical Isotopes Program, Isotope Dept. Group, Oak Ridge National Laboratory (ORNL), Oak Ridge (United States)

2015-06-15

This review provides a comprehensive summary of the production of {sup 177}Lu to meet expected future research and clinical demands. Availability of options represents the cornerstone for sustainable growth for the routine production of adequate activity levels of {sup 177}Lu having the required quality for preparation of a variety of {sup 177}Lu-labeled radiopharmaceuticals. The tremendous prospects associated with production of {sup 177}Lu for use in targeted radionuclide therapy (TRT) dictate that a holistic consideration should evaluate all governing factors that determine its success. While both “direct” and “indirect” reactor production routes offer the possibility for sustainable {sup 177}Lu availability, there are several issues and challenges that must be considered to realize the full potential of these production strategies. This article presents a mini review on the latest developments, current status, key challenges and possibilities for the near future. A broad understanding and discussion of the issues associated with {sup 177}Lu production and processing approaches would not only ensure sustained growth and future expansion for the availability and use of {sup 177}Lu-labeled radiopharmaceuticals, but also help future developments.

Measurement of the cross sections for the 175Lu(n,2n)174m,gLu reaction

International Nuclear Information System (INIS)

Yu Weixiang; Zhao Wenrong; Lu Hanlin; Han Xiaogang

1998-01-01

The 175 Lu(n,2n) 174m,g Lu reaction is an important indicator. There are 10 sets of measured data since 1960 (total 58 experimental values). Most of the data are finished at 14 MeV with 20%∼30% discrepancy. So the authors measured the cross section by activation method in neutron energies of 14 MeV and 10∼12 MeV. The measurement is carried out at the Cockcroft-Walton and HI-13 Tandem accelerator of CIAE

High-Spin Structure in Odd-Odd 160Lu Nucleus

International Nuclear Information System (INIS)

Wang Lie-Lin; Lu Jing-Bin; Yang Dong; Ma Ke-Yan; Yin Li-Chang; Zhou Yin-Hang; Wu Xiao-Guang; Wen Shu-Xian; Li Guang-Sheng; Yang Chun-Xiang

2012-01-01

The high-spin states of 160 Lu are populated by the fusion-evaporation reaction 144 Sm( 19 F,3n) 160 Lu at beam energies of 90 and 106 MeV. A new level scheme of 160 Lu is established. A possible isomeric state based on the πh 11/2 νh 9/2 configuration is observed. The new decoupled band with the configuration of πd 3/2 [411]1/2 + νi 13/2 [660]1/2 + is established, and the configurations of these similar decoupled bands in the neighboring odd-odd 162−166 Lu nuclei are suggested. A positive parity coupled band is assigned as the πd 5/2 [402]5/2 + νi 13/2 [660]1/2 + configuration. (nuclear physics)

Biferroic LuCrO{sub 3}: Structural characterization, magnetic and dielectric properties

Energy Technology Data Exchange (ETDEWEB)

Durán, A., E-mail: dural@cnyn.unam.mx [Universidad Nacional Autónoma de México, Centro de Nanociencias y Nanotecnología, Km. 107 Carretera Tijuana-Ensenada, Apartado Postal 14, C.P. 22800 Ensenada, BC (Mexico); Meza F, C.; Morán, E.; Alario-Franco, M.A. [Departamento de Química Inorgánica y Laboratorio Complutense de Altas Presiones, Facultad de Química, Universidad Complutense de Madrid, EU, 28040 Madrid (Spain); Ostos, C., E-mail: ceostoso@gmail.com [Instituto de Química, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín (Colombia)

2014-02-14

Multiferroic LuCrO{sub 3} perovskite-type structure (Pbnm) obtained via auto-ignition synthesis was characterized by a combination of X-ray diffraction (XRD) and thermogravimetric (TG) techniques, and through magnetization and permittivity measurements. Results showed that amorphous combustion powders were fully transformed to orthorhombic LuCrO{sub 3} structure at 1200 K after the first LuCrO{sub 4} crystallization at 700 K. The magnetic response displays thermal irreversibility between zero-field-cooling and field-cooling condition which is due to spin canted AF switching at 116 K. Accordingly, a hysteresis loop in the M(H) data confirms weak ferromagnetism in LuCrO{sub 3}. On the other hand, the permittivity measurement shows a broad peak transition typical of relaxor-type ferroelectrics transition at ∼450 K. Electrical conductivity increases as temperature increases showing an anomaly around the diffuse phase transition. The diffuse phase transition and the formation of the charge carriers are discussed in terms of a local distortion around the Lu Site. - Highlights: • Multiferroic LuCrO{sub 3} was successfully obtained via auto-ignition synthesis. • Amorphous powder is transformed first to LuCrO{sub 4} (700 K) and next to LuCrO{sub 3} (1100 K). • The CrO{sub 6} octahedra are tilted away and rotates from the ideal octahedral shape. • LuCrO{sub 3} exhibits a canted AFM transition (116 K) and a relaxor ferroelectric behavior. • Tilting and rotation of CrO{sub 6} octahedra influenced transport properties on LuCrO{sub 3}.

Optical and scintillating properties of Ce:Li(Y,Lu)F4 single crystals

International Nuclear Information System (INIS)

Yokota, Yuui; Kurosawa, Shunsuke; Chani, Valery; Kamada, Kei; Yoshikawa, Akira

2014-01-01

We have investigated the optical and scintillating properties of Lu co-doped Ce:LiYF 4 single crystals with various Lu content. In the transmittance and absorption spectra, the absorption peaks at 243 nm get systematically red shifted in contrast to the peaks at 197 and 200 nm which get blue shifted with the increase in Lu content. At the same time, emission peaks at 306 nm and 200 nm under 295 nm excitation also get red shifted. The decay time of Ce:Li(Y,Lu)F 4 crystals under 295 nm excitation is found to be faster than that of Ce:LiYF 4 and Ce:LiLuF 4 crystals. The alpha-peak positions in the pulse-height spectra and decay times of crystals under alpha-ray irradiation are found to vary with the Lu content. - Highlights: • Optical and scintillation properties of Ce:Li(Y 1-x Lu x )F 4 crystals were inspected. • Increase of Lu content resulted change of the position of four absorption peaks. • Admixing of Y and Lu decreased the light yield and increased the decay time. • The Ce:LiLuF 4 crystal indicated the largest light yield in the pulse-height spectra. • Li[(Y 0.8 Lu 0.2 ) 0.98 Ce 0.02 ]F 4 indicated larger light yield than Ce:LiYF 4 crystal

Pseudo-spin band in the odd-odd nucleus sup 1 sup 7 sup 2 Lu

CERN Document Server

Venkova, T; Gast, W; Podsvirova, E O; Jäger, H M; Mihailescu, L; Bazzacco, D; Menegazzo, R; Lunardi, S; Alvarez, C R; Ur, C; Martínez, T; Angelis, G D; Axiotis, M; Napoli, D; Urban, W; Rzaca-Urban, T; Frauendorf, S

2003-01-01

High-spin states in the odd-odd nucleus sup 1 sup 7 sup 2 Lu have been populated in a sup 1 sup 7 sup 0 Er( sup 7 Li,5n) reaction and the emitted gamma-radiation was detected with the GASP array. Two sequences of a new identical band have been observed with the transition energies in the favoured and unfavoured sequences being identical within approx 3 keV at low spins and approx 1 keV at high spins over the whole observed spin range. An interpretation as a pseudo-spin singlet band of pi 1/2 sup - [541] x nu 1/2 sup - [420] configuration is proposed. It represents the best example of a pseudo-spin singlet band in normal deformed nuclei known until now.

Absence of justice : Lu Chengming's struggle for compensation

Energy Technology Data Exchange (ETDEWEB)

Bai, L.

2008-03-10

This article described the efforts of Chinese citizen Lu Chengming to claim compensation from the Chinese government after being forcibly re-located during the building of the Three Gorges hydroelectric project. Research conducted by the author revealed that many households were not compensated for being resettled, and that many people who had lived in the region became refugees. Lu Chengming's family became unemployed after his hotel was demolished in 2002. The family of 11 was then divided into 4 in order to further reduce the amount of subsidies owed to them. Appeals to higher authorities began in 1993. Since then, Lu Chengming has only received the most basic welfare assistance. This article provided a translation of Lu Chengming's testimony as well as his account of the resettlement procedures. It was concluded that while the Chinese government consistently refuses his claims, Lu Chengming continues to live in hope that the government will award him his settlement. 4 refs., 3 figs.

Inflammation and ER Stress Downregulate BDH2 Expression and Dysregulate Intracellular Iron in Macrophages

Directory of Open Access Journals (Sweden)

Susu M. Zughaier

2014-01-01

Full Text Available Macrophages play a very important role in host defense and in iron homeostasis by engulfing senescent red blood cells and recycling iron. Hepcidin is the master iron regulating hormone that limits dietary iron absorption from the gut and limits iron egress from macrophages. Upon infection macrophages retain iron to limit its bioavailability which limits bacterial growth. Recently, a short chain butyrate dehydrogenase type 2 (BDH2 protein was reported to contain an iron responsive element and to mediate cellular iron trafficking by catalyzing the synthesis of the mammalian siderophore that binds labile iron; therefore, BDH2 plays a crucial role in intracellular iron homeostasis. However, BDH2 expression and regulation in macrophages have not yet been described. Here we show that LPS-induced inflammation combined with ER stress led to massive BDH2 downregulation, increased the expression of ER stress markers, upregulated hepcidin expression, downregulated ferroportin expression, caused iron retention in macrophages, and dysregulated cytokine release from macrophages. We also show that ER stress combined with inflammation synergistically upregulated the expression of the iron carrier protein NGAL and the stress-inducible heme degrading enzyme heme oxygenase-1 (HO-1 leading to iron liberation. This is the first report to show that inflammation and ER stress downregulate the expression of BDH2 in human THP-1 macrophages.

Řízení procesu reaktivního magnetronového naprašování

OpenAIRE

Dušek, Jan

2014-01-01

Bakalářská práce stručně popisuje technologii reaktivního magnetronového naprašování a zabývá se návrhem a realizací programu k jeho ovládání. K tomuto účelu byl vytvořen ovládací program pro řízení jednotlivých komponent aparatury PLS160 v programovacím prostředí LabView. Na základě znalostí technologického procesu a postupu reaktivního magnetronového naprašování byl vytvořen automatický program. Tento automatický program je možné modifikovat pomocí receptů. Vedle programové skladby byly pro...

Luminescence and scintillation properties of LuPO4-Ce nanoparticles

International Nuclear Information System (INIS)

Vistovskyy, V.; Malyy, T.; Pushak, A.; Vas’kiv, A.; Shapoval, A.; Mitina, N.; Gektin, A.; Zaichenko, A.; Voloshinovskii, A.

2014-01-01

Study of the spectral-luminescence parameters of LuPO 4 -Ce nanoparticles upon the excitation by X-ray quanta and synchrotron radiation with photon energies of 4–25 eV was performed. Nanoparticles with mean size about a=35 nm and nanoparticles with size less than 12 nm reveal the different structures of cerium centers. Luminescence efficiency of LuPO 4 -Ce nanoparticles of a 4 -Ce nanoparticles studied using synchrotron and X-ray excitation. • Different structure of Ce 3+ -centers has been revealed for LuPO 4 -Ce nanoparticles. • Luminescence of LuPO 4 -Ce with size less than 12 nm is strongly quenched upon the X-ray excitation

The infrared radiation spectrum of acupoint taiyuan (LU 9) in asthma patients.

Science.gov (United States)

Zhou, Yu; Shen, Xue-yong; Wang, Li-zhen; Wei, Jian-zi; Cheng, Ke

2012-06-01

To analyze the distinctive pathological characteristics in the spectrums of spontaneous infrared radiation at the Taiyuan (LU 9) acupoint in patients with asthma. A highly sensitive infrared spectrum detecting device was used to detect the spectrums of spontaneous infrared radiation at Taiyuan (LU 9) in 37 asthma patients and 34 healthy volunteers. Asthma patients had significantly lower infrared intensity than that of the healthy volunteers (P>0.01). Asthma patients had significantly lower overall infrared radiation intensity at the left Taiyuan (LU 9) than that of healthy volunteers (P > 0.05), but there was no significant difference between healthy volunteers and asthma patients at the right Taiyuan (LU 9) (P > 0.05). The infrared radiation intensity of 17 wavelength spots at the left Taiyuan (LU 9) and 4 wavelength spots at the right Taiyuan (LU 9) in asthma patients were significantly lower than those of healthy volunteers (P > 0.05). At 2 microm, the infrared radiation intensity of asthma patients was significantly stronger than that of healthy volunteers (P > 0.05). At 19 wavelength spots in the healthy volunteers and at 4 wave-length spots in the asthma patients, the left Taiyuan (LU 9) showed a significantly stronger intensity than that of the right Taiyuan (LU 9) (P > 0.05S). By Pearson's chi2 test, healthy volunteers had more wavelength spots that were significantly different between the left and right Taiyuan (LU 9) than the asthma patients (P > 0.01). Changes in the infrared spectrum at the Taiyuan (LU 9) acupoint in asthma patients may reflect distinct pathological changes. Certain acupuncture points may be related to specific organs.

Synthesis of DOTMP and biodistribution and imaging study of 177-Lu-DOTMP

International Nuclear Information System (INIS)

Deng Xinrong; Luo Zhifu; Xiang Xueqin; Li Fenglin; Fan Caiyun; Liu Zihua; Ye Zhaoyun; Li Hongyu; Chen Yang; Zhuang Ling

2012-01-01

Cyclen (1, 4, 7, 10-tetraazacyclododecane) and H 3 PO 3 was used to synthesis DOTMP (1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-Tetraamino methylenephosphonate). 177 Lu was produced by irradiating enriched lutetium oxide ( 176 Lu 2 O 3 ) with thermal neutron flux of 2' × 10 13 n/cm 2 /S in swimming pool reactor (SPR) for 10 days. And then DOTMP was labelled by 177 Lu. The biodistribution of 177 Lu-DOTMP in model mice bearing S180 sarcoma and SPECT imaging in Japanese white rabbit were also carried out. The results showed that the total activity of 177 LuCl 3 solution obtained was 9.19 × 10 5 MBq after corresponding chemical process. According to the optimal condition of the labeling experiment, the labelling efficiency of 177 Lu-DOTMP was 99.4%. The results of biodistribution study indicated that 177 Lu-DOTMP eliminated rapidly from blood and was delivered to target bone. The radioactivity uptake was mainly in bone and less in other viscera. The results of SPECT imaging showed that the radioactivity was accumulated in bladder. 177 Lu-DOTMP was mainly excreted by kidney. The uptake of the activity in the skeleton was observed within 22 h postinjection and it became quite significant at 46 h post injection. It indicated that 177 Lu-DOTMP has good bone targeting and is worthy of further research. (authors)

Progress in the development of LuAlO$_{3}$ based scintillators

CERN Document Server

Belsky, A; Lecoq, P; Dujardin, C; Garnier, N; Canibano, H; Pédrini, C; Petrosian, A

2000-01-01

LuAlO/sub 3/:Ce/sup 3+/ (LuAP) and Lu/sub x/Y/sub 1/-xAlO/sub 3/:Ce /sup 3+/ (LuYAP) crystals are used as scintillation materials for positron emission tomography. The actual study of these scintillators develops in three directions: (i) growth of large size LuAP crystals with stable properties, (ii) the relationship between the composition of LuYAP crystals and scintillation properties, and (iii) scintillation mechanisms in lutetium compounds. After improving of growth conditions a large size samples (length >40 mm) have been prepared. Crystals show a good correlation between growth parameters, light yield and transmission spectra. We studied a series of samples with calibrated size (2*2*10 mm3) and compare the light yield with standard BGO and LSO samples. Mixed crystals with composition of 0.6

AN ELISA ASSAY FOR HEME OXYGENASE (HO-1)

Science.gov (United States)

An ELISA assay for heme oxygenase (HO-l ) Abstract A double antibody capture ELISA for the HO-l protein has been developed to separately quantitate HO-I protein. The use of 2.5% NP40 detergent greatly assists in freeing HO-l protein from membranes and/or other cel...

Rab7a modulates ER stress and ER morphology.

Science.gov (United States)

Mateus, Duarte; Marini, Elettra Sara; Progida, Cinzia; Bakke, Oddmund

2018-05-01

The Endoplasmic Reticulum (ER) is a membranous organelle with diverse structural and functional domains. Peripheral ER includes interconnected tubules, and dense tubular arrays called "ER matrices" together with bona fide flat cisternae. Transitions between these states are regulated by membrane-associated proteins and cytosolic factors. Recently, the small GTPases Rab10 and Rab18 were reported to control ER shape by regulating ER dynamics and fusion. Here, we present evidence that another Rab protein, Rab7a, modulates the ER morphology by controlling the ER homeostasis and ER stress. Indeed, inhibition of Rab7a expression by siRNA or expression of the dominant negative mutant Rab7aT22 N, leads to enlargement of sheet-like ER structures and spreading towards the cell periphery. Notably, such alterations are ascribable neither to a direct modulation of the ER shaping proteins Reticulon-4b and CLIMP63, nor to interactions with Protrudin, a Rab7a-binding protein known to affect the ER organization. Conversely, depletion of Rab7a leads to basal ER stress, in turn causing ER membrane expansion. Both ER enlargement and basal ER stress are reverted in rescue experiments by Rab7a re-expression, as well as by the ER chemical chaperone tauroursodeoxycholic acid (TUDCA). Collectively, these findings reveal a new role of Rab7a in ER homeostasis, and indicate that genetic and pharmacological ER stress manipulation may restore ER morphology in Rab7a silenced cells. Copyright © 2018 Elsevier B.V. All rights reserved.

Návrh slaďování pracovního a soukromého života ve vybrané organizaci

OpenAIRE

Majerčíková, Andrea

2014-01-01

Cílem diplomové práce je analyzovat strategii vybrané soukromé organizace v oblasti slaďování pracovního a osobního života a navrhnout opatření ke zlepšení stávajícího stavu. Práce specifikuje pojmy jako konflikt rolí v rámci pracovního a osobního života, gender a politika rovných příležitostí, koncept „flexicurity“ a dále nastiňuje různorodá opatření napomáhající slaďování pracovního a soukromého života. V rámci analýzy bylo využito dotazníkového šetření a rozhovoru s manažerkou vybrané orga...

Crystal growth, spectroscopic and laser properties of Tm:LuAG crystal

Science.gov (United States)

Xu, X. D.; Wang, X. D.; Lin, Z. F.; Cheng, Y.; Li, D. Z.; Cheng, S. S.; Wu, F.; Zhao, Z. W.; Gao, C. Q.; Gao, M. W.; Xu, J.

2009-11-01

Tm:Lu3Al5O12 (Tm:LuAG) crystal was grown by the Czochralski method. The segregation coefficient was measured by Inductively Coupled Plasma Atomic Emission Spectrometer. The cell parameters were analyzed with X-ray powder diffraction experiments. The absorption and fluorescence spectra of Tm:LuAG crystal at room temperature were investigated. With a 20 W fiber-coupled diode laser as pump source, the continuous-wave (CW) laser action of Tm:LuAG crystal was demonstrated. The maximum output power at 2020 nm was obtained to be 3.04 W, and the slope efficiency was 25.3%.

Návrh algoritmu automatického parkování pro experimentální vozidlo se čtyřmi řízenými koly

OpenAIRE

Vrbková, Michaela

2016-01-01

Bakalářská práce je zaměřena na tvorbu parkovacího asistenta určeného pro podélné parkování vozidla s přední i zadní natáčecí nápravou (dále jen 4WS). V bakalářské práci je provedena rešerže v oblasti 4WS kinematiky a dostupných senzorů pro parkování. Součástí bakalářské práce je nově vytvořený software pro zaznamenání trajektorií 4WS automobilu včetně popisu jeho funkčnosti. Výsledkem bakalářské práce je algoritmus pro parkovacího asistenta, který byl teoreticky simulován v programu Matlab a...

PLC SCADA systém pro řízení větrného tunelu

OpenAIRE

Trenčan, Tomáš

2017-01-01

Předložená bakalářská práce se věnuje programovatelnému automatu (PLC) firmy WAGO a SCADA systémům. Skládá se ze dvou části, z teoretické části a z praktické části. V teoretické části jsou na zakladě poznatků z odborné literatury vymezeny pojmy ohledně SCADA systémů, PLC od firmy WAGO a vývojového prostředí e!COCKPIT firmy WAGO a rešerše volně dostupných SCADA systémů podporujících Modbus TCP. Na základě této rešerše byl vybrán SCADA systém pro vizualizaci dvou demonstračníc úloh v praktické ...

Proton drip-line studies at HRIBF

International Nuclear Information System (INIS)

Rykaczewski, K.P.; Batchelder, J.C.; Bingham, C.R.; Bryan, R.E.; Davinson, T.; Woods, P.J.; Ginter, T.N.; Hamilton, J. H.; Gross, C.J.; Grzywacz, R.; Janas, Z.; Karny, M.; MacDonald, B.D.; McConnell, J.W.; Toth, K.S.; Piechaczek, A.; Zganjar, E.F.; Szerypo, J.; Walters, W. B.

2000-01-01

Proton radioactivity studies performed at the Holifield Radioactive Ion Beam Facility (HFBR) within the last few years are reviewed. The discovery of five new proton radioactivities 140 Ho, 141m Ho, 145 Tm, 150m Lu and 151m Lu is presented together with a recent observation of fine structure in proton emission from 146gs,m Tm. These proton emitters were produced by means of fusion-evaporation reactions and studied with the HFBR Recoil Mass Separator and detection system based on a Double-sided Silicon Strip Detector. For 113 Cs and 151 Lu, the studies of level structure were extended beyond the proton-emitting states via the measurements with a clover array Clarion using Recoil Decay Tagging

Lu{sub 2}O{sub 3}:Tb,Hf storage phosphor

Energy Technology Data Exchange (ETDEWEB)

Kulesza, Dagmara; Trojan-Piegza, Joanna [Faculty of Chemistry, University of Wroclaw, 14 F. Joliot-Curie Street, 50-383 Wroclaw (Poland); Zych, Eugeniusz, E-mail: zych@wchuwr.p [Faculty of Chemistry, University of Wroclaw, 14 F. Joliot-Curie Street, 50-383 Wroclaw (Poland)

2010-03-15

Lu{sub 2}O{sub 3}:Tb,Hf ceramics containing 0.1% of Tb and 0-1.5% of Hf were prepared in reducing atmosphere at 1700 {sup o}C and their thermoluminescence properties were systematically studied. For comparison Tb,Ca co-doped specimen was also fabricated and investigated. The Tb,Hf ceramics shows basically a single TL band located around 180 {sup o}C as found with heating rate of 15 {sup o}C/min. Ceramics singly doped with Tb show complex TL glow curves indicating the presence of traps of very different depths. On the other hand Tb,Ca co-doping is beneficial for the development of shallow traps with the main TL band around 70 {sup o}C. Hence, the aliovalent impurities, Ca{sup 2+} and Hf{sup 4+}, strongly influenced the traps structure in Lu{sub 2}O{sub 3}:Tb ceramics, each of them in its own specific way. Isothermal decay of Lu{sub 2}O{sub 3}:Tb,Hf at 185 {sup o}C was recorded and its shape suggest that multiple hole trapping occurs in the Lu{sub 2}O{sub 3}:Tb,Hf ceramics. Due to the different traps depths the Lu{sub 2}O{sub 3}:Tb,Hf ceramics possess properties typical for storage phosphors, while Lu{sub 2}O{sub 3}:Tb,Ca is a persistent luminescent material rather.

Nekonvenční metody zpracování nožířských materiálů

OpenAIRE

Bražina, Jakub

2017-01-01

Tato práce se zaobírá problematikou nekonvenčních nožířských materiálu a jejich následnou aplikaci pro výrobu a zpracování loveckého nože. V rešeršní části je čtenáři přiblížena nožířská problematika, kde jsou uvedeny základní konstrukční charakteristiky a potřebné vlastnosti nože. V další části práce jsou popsány různé kovové i nekovové materiály, jejich vlastnosti, případné zpracování a výroba. Dále se práce zabývá problematikou povrchové ochrany těchto nožířských materiálu. Práce se také z...

Mobility of rare earth element in hydrothermal process and weathering product: a review

Science.gov (United States)

Lintjewas, L.; Setiawan, I.

2018-02-01

The Rare Earth Element (REE), consists of La, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Lu, Ho, Er, Tm, Yb, are important elements to be used as raw materials of advanced technology such as semiconductors, magnets, and lasers. The research of REE in Indonesia has not been done. Several researches were conducted on granitic rocks and weathering product such as Bangka, Sibolga, West Kalimantan, West Sulawesi and Papua. REE can be formed by hydrothermal processes such as Bayan Obo, South China. The REE study on active hydrothermal system (geothermal) in this case also has the potential to produce mineral deposits. The purpose of this review paper is to know the mobility of REE on hydrothermal process and weathering products. Mobility of REE in the hydrothermal process can change the distribution patterns and REE content such as Ce, Eu, La, Lu, Nd, Sm, and Y. Another process besides the hydrothermal is weathering process. REE mobility is influenced by weathering products, where the REE will experience residual and secondary enrichment processes in heavier minerals.

Study on the eγ coincidences in the 169Lu decay

International Nuclear Information System (INIS)

Batsev, S.; Bonch-Osmolovskaya, N.A.; Budzyak, A.; Kuznetsov, V.V.; Usmanov, R.R.

1979-01-01

The 169 Lu→ 169 Yb decay scheme was analyzed on the basis of measurements of eγ coincidence. The 169 Lu sources were obtained by irradiating a tantalum target by 660 MeV protons. The eγ-coincidence spectra were measured by an ironless β-spectrometer with a toroidal magnetic field and a detector. The γ-ray and eγ-coincidence spectra were processed by a computer. The results of processing the 169 Lu coincidence spectra are tabulated. No excited states of 169 Yb not confirmed by γγ and eγ coincidences (except for the head level of the 3/2 + (651) 720 keV band) remain in the 169 Lu decay scheme proposed. Weak transitions with the total intensity of no more than 3.3% per a 169 Lu decay have remained unarranged, they should discharge weakly excited levels of 169 Yb. Probabilities of the 169 Yb level population per a 169 Lu decay and the corresponding values of probabilities of transitions in them are presented. As a whole, the 169 Lu decay scheme involves 60 levels, 31 states of them are new

Optical spectroscopy and luminescence quenching of LuI3:Ce3+

International Nuclear Information System (INIS)

Birowosuto, M.D.; Dorenbos, P.; Haas, J.T.M. de; Eijk, C.W.E. van; Kraemer, K.W.; Guedel, H.U.

2006-01-01

Optical spectroscopy of LuI 3 doped with Ce 3+ using ultraviolet and visible light excitation is reported. LuI 3 host excitation and emission and 4f-5d excitation and emission of Ce 3+ are observed. An empirical model based on crystal field splitting was used to estimate the energy of the highest 4f-5d excitation band. The crystal field splitting and centroid shift were compared to those of LuCl 3 :Ce 3+ and LuBr 3 :Ce 3+ . Temperature dependence of X-ray excited luminescence spectra shows thermal quenching, whereas that of the decay curve of Ce 3+ emission excited at the lowest 5d band of Ce 3+ does not indicate the presence of quenching of Ce 3+ emission for temperature below 625K. The quenching in LuI 3 :Ce 3+ therefore occurs before the 5d Ce 3+ emission takes place

Posouzení účinnosti filtračního materiálu DMI-65 na odstraňování kovů z vody

OpenAIRE

Konečný, Jiří

2016-01-01

Diplomová práce se v první kapitole zabývá různými vodárenskými procesy, kterými je možno odstranit sloučeniny kovů a polokovů z vody. Podstatná část je věnována filtračním materiálům, mezi něž se řadí v celku nový filtrační materiál DMI-65. Filtračnímu materiálu DMI-65 je věnována obsáhlá kapitola, která podrobně popisuje vlastnosti, charakter a použití v praxi. Další kapitola práce popisuje průběh poloprovozní zkoušky materiálu DMI-65 na úpravně vody v Ivančicích. Na závěr je popsána labora...

Crystal growth, spectral and laser properties of Nd:LuAG single crystal

International Nuclear Information System (INIS)

Xu, X D; Meng, J Q; Cheng, Y; Li, D Z; Cheng, S S; Wu, F; Zhao, Z W; Wang, X D; Xu, J

2009-01-01

Nd:LuAG (Nd:Lu 3 Al 5 O 12 ) crystal was grown by the Czochralski method. X-ray powder diffraction experiments show that the Nd:LuAG crystal crystallizes in the cubic with space group Ia3d and has the cell parameter: a = 1.1907 nm, V = 1.6882 nm 3 . The absorption and fluorescence spectra of Nd:LuAG crystal at room temperature were investigated. With a fiber-coupled diode laser as pump source, the continuous-wave (CW) laser action of Nd:LuAG crystal was demonstrated. The maximum output power at 1064 nm was obtained to be 3.8 W under the incident pump power of 17.3 W, with the optical conversion efficiency 22.0% and the slope efficiency 25.7%

Crystal growth, spectral and laser properties of Nd:LuAG single crystal

Science.gov (United States)

Xu, X. D.; Wang, X. D.; Meng, J. Q.; Cheng, Y.; Li, D. Z.; Cheng, S. S.; Wu, F.; Zhao, Z. W.; Xu, J.

2009-09-01

Nd:LuAG (Nd:Lu3Al5O12) crystal was grown by the Czochralski method. X-ray powder diffraction experiments show that the Nd:LuAG crystal crystallizes in the cubic with space group Ia3d and has the cell parameter: a = 1.1907 nm, V = 1.6882 nm3. The absorption and fluorescence spectra of Nd:LuAG crystal at room temperature were investigated. With a fiber-coupled diode laser as pump source, the continuous-wave (CW) laser action of Nd:LuAG crystal was demonstrated. The maximum output power at 1064 nm was obtained to be 3.8 W under the incident pump power of 17.3 W, with the optical conversion efficiency 22.0% and the slope efficiency 25.7%.

Incorporation of Pr into LuAG ceramics

Science.gov (United States)

Marchewka, M. R.; Chapman, M. G.; Qian, H.; Jacobsohn, L. G.

2017-06-01

An investigation of the effects of Pr in (Lu1-xPrx)3Al5O12 (LuAG:Pr) ceramics was carried out by means of x-ray diffraction (XRD), energy dispersive x-ray spectroscopy (EDX), and attenuated total reflection Fourier transform infrared spectroscopy (ATR FTIR) measurements coupled with luminescence measurements. It was found that the Pr concentration that maximizes luminescence emission depends on the thermal processing conditions. While the calcined LuAG:Pr powder showed maximum luminescence emission for Pr concentrations between 0.18 and 0.33 at.%, maximum emission of ceramic bodies sintered at 1500 °C for 20 h was obtained with Pr concentrations between 0.018 and 0.18 at.%. Further, for short sintering times up to about 3 h, luminescence emission intensity is maximum for Pr concentrations around 0.33 at.%. Longer sintering times lead to the formation of PrAlO3 as a secondary phase, concomitant with a reduction of the intensity of luminescence emission.

Neutron and resonant x-ray scattering studies of RNi2B2C (R = rare earth) single crystals

International Nuclear Information System (INIS)

Stassis, C.; Goldman, A.I.; Iowa State Univ., Ames, IA

1996-01-01

This family of intermetallic compounds is ideal for the study of the interplay between superconductivity and magnetism since, in several of these compounds (Ho, Er, Tm, Dy), superconductivity coexists with magnetic ordering. The most important findings of the scattering studies are (a) in the Ho-compound, a complex magnetic structure characterized by two incommensurate wave vectors, rvec k a = 0.585 rvec a* and rvec k c = 0.915 rvec c*, exists in the vicinity of 5 K, where the almost reentrant behavior of this compound occurs; (b) an incommensurate magnetic structure with wave vector along rvec a*, close to the zone boundary, is observed in several of these compounds; and (c) pronounced soft-phonon behavior was observed for both the acoustic and first optical Δ 4 [ξ00] branches in the superconducting Lu and Ho compounds, a behavior characteristic of strongly coupled conventional superconductors. Furthermore, these phonon anomalies occur at wave vectors close to those of the incommensurate magnetically ordered structures observed in the magnetic compounds of this family. This observation suggests that both the magnetic ordering and phonon softening originate from common nesting features of the Fermi surfaces of these compounds. Band theoretical calculations are in qualitative agreement with these results

Determination of lanthanides in fossil samples using laser induced breakdown spectroscopy

International Nuclear Information System (INIS)

Anzano, J.M.; Lasheras, R.J.; Canudo, I.; Laguna, M.

2017-01-01

As being a fast, simple and relatively non-destructive analytical technique Laser-induced breakdown spectroscopy (LIBS) has a large variety of applications including the analysis of paleontological samples. In this work LIBS is employed for the quantitative determination of lanthanides (Ce, Dy, Er, Eu, Gd, Ho, La, Lu, Nd, Sm, Tb, Tm and Yb) in vertebrate fossil samples comprising teeth, disarticulated complete or fragmented bones, eggshell fragments, and coprolites of dinosaurs, mammals and crocodiles. For emission line data, standard AnalaR grade salts of lanthanides were used. The major components: iron, calcium, magnesium, silicon and aluminum in the samples were also determined. The analytical information may be helpful in studying the samples for their age, formation environment and other paleontological properties. (author)

Isopiestic determination of the activity coefficients of some aqueous rare earth electrolyte solutions at 250C. I. The rare earth chlorides

International Nuclear Information System (INIS)

Spedding, F.H.; Weber, H.O.; Saeger, V.W.; Petheram, H.H.; Rard, J.A.; Habenschuss, A.

1976-01-01

The osmotic coefficients of the aqueous trichlorides of La, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, and Y were determined from 0.1 M to saturation at 25 0 C. Semiempirical least-squares equations were obtained for the osmotic coefficients as a function of molality and these equations were used to calculate water activities and mean molal activity coefficients. The water activities of the light rare earth chlorides at constant molalities are higher than for the heavy rare earths, while the mean molal activity coefficients are larger for the heavy rare earths than for the light ones. The above effects are discussed in terms of changes in the cationic radii and hydration of the rare earth ions

LuIII parvovirus selectively and efficiently targets, replicates in, and kills human glioma cells.

Science.gov (United States)

Paglino, Justin C; Ozduman, Koray; van den Pol, Anthony N

2012-07-01

Because productive infection by parvoviruses requires cell division and is enhanced by oncogenic transformation, some parvoviruses may have potential utility in killing cancer cells. To identify the parvovirus(es) with the optimal oncolytic effect against human glioblastomas, we screened 12 parvoviruses at a high multiplicity of infection (MOI). MVMi, MVMc, MVM-G17, tumor virus X (TVX), canine parvovirus (CPV), porcine parvovirus (PPV), rat parvovirus 1A (RPV1A), and H-3 were relatively ineffective. The four viruses with the greatest oncolytic activity, LuIII, H-1, MVMp, and MVM-G52, were tested for the ability, at a low MOI, to progressively infect the culture over time, causing cell death at a rate higher than that of cell proliferation. LuIII alone was effective in all five human glioblastomas tested. H-1 progressively infected only two of five; MVMp and MVM-G52 were ineffective in all five. To investigate the underlying mechanism of LuIII's phenotype, we used recombinant parvoviruses with the LuIII capsid replacing the MVMp capsid or with molecular alteration of the P4 promoter. The LuIII capsid enhanced efficient replication and oncolysis in MO59J gliomas cells; other gliomas tested required the entire LuIII genome to exhibit enhanced infection. LuIII selectively infected glioma cells over normal glial cells in vitro. In mouse models, human glioblastoma xenografts were selectively infected by LuIII when administered intratumorally; LuIII reduced tumor growth by 75%. LuIII also had the capacity to selectively infect subcutaneous or intracranial gliomas after intravenous inoculation. Intravenous or intracranial LuIII caused no adverse effects. Intracranial LuIII caused no infection of mature mouse neurons or glia in vivo but showed a modest infection of developing neurons.

Gamma radiation exposure of accompanying persons due to Lu-177 patients

Directory of Open Access Journals (Sweden)

Kovan Bilal

2015-01-01

Full Text Available Neuroendocrine tumours (NET are cancers usually observed and arisen in the stomach, intestine, pancreas and breathing system. Recently, radionuclide therapy applications with Lu-177 peptide compound are rapidly growing; especially effective clinical results are obtained in the treatment of well-differentiated and metastatic NET. In this treatment, Lu-177-DOTA, a beta emitter radioisotope in the radiopharmaceutical form, is given to the patient by intravenous way. Lu-177 has also gamma rays apart from beta rays. Gamma rays have 175 keV average energy and these gamma rays should be under the control in terms of radiation protection. In this study, we measured the exposure dose from the Lu-177 patient.

First observation of yrast band in odd-odd 162Lu

International Nuclear Information System (INIS)

Zhang, Y.H.; Yuan, G.J.; Liu, X.A.

1996-01-01

High spin states of the odd-odd 162 Lu nucleus have been studied via 147 Sm( 19 F, 4nγ) 162 Lu reaction at 95MeV beam energy. Level scheme for yrast band based on π[h 11/2 ] υ[i 13/2 ] quasiparticle configuration was established up to I π =(23 - ) for the first time. This band shows the signature inversion in energy before backbending generally appeared in this mass region. It is stressed that the signature splitting in 162 Lu is larger than that in the 160 Tm nucleus. (orig.)

Beyond band termination in 157Er and the search for wobbling excitations in strongly deformed 174Hf

International Nuclear Information System (INIS)

Riley, M A; Djongolov, M K; Evans, A O

2005-01-01

High-spin terminating bands in heavy nuclei were first identified in nuclei around 158 Er 90 . While examples of special terminating states have been identified in a number of erbium isotopes, almost nothing is known about the states lying beyond band termination. In the present work the high-spin structure of 157 Er has been studied using the Gammasphere spectrometer. The subject of triaxial superdeformation and 'wobbling' modes in Lu nuclei has rightly attracted a great deal of attention. Very recently, four strongly or superdeformed (SD) sequences have been observed in 174 Hf and ultimate cranker calculations predict such structures may have significant triaxial deformation. We have performed two experiments in an attempt to verify the possible triaxial nature of these bands. A lifetime measurement was performed to confirm the large (and similar) deformation of the bands. In addition, a high-statistics, thin-target experiment was run to search for linking transitions between the SD bands and possible wobbling modes

Mälu sildistamine / Erkki Bahovski

Index Scriptorium Estoniae

Bahovski, Erkki, 1970-

2007-01-01

President Toomas Hendrik Ilvese üleskutsest moodustada Mälu Instituut Eesti lähimineviku uurimiseks. Autori arvates on Vene propaganda taustal raske uurida ajalugu sine ira et studio ("ilma viha ja eelarvamusteta"), nagu soovitas president

Absorbed dose profiles for 32P, 90Y, 188Re, 177Lu, 51Cr, 153Sm and 169Er: radionuclides used in radiosynoviortheses treatment

International Nuclear Information System (INIS)

Torres, M.; Ayra, E.; Albuerne, O.; Delgado, M.

2008-01-01

The remarkable advances in the design and synthesis of radiopharmaceuticals has created the opportunity of generating new agents for the treatment of radiosynoviortheses (RSV) which exhibit a minimum leakage from the synovial joint reducing, this way, the non desired absorbed doses to non target organs such as liver, spleen, kidney. Nowadays, the variety of beta emitters used in RSV ranges between 0.34 MeV - 0.33 mm penetration in tissue ( 169 Er) and 2.27 MeV - 3.6 mm penetration in tissue ( 90 Y). The half life of these isotopes goes from 2.3 hours ( 165 Dy) to 27.8 days ( 51 Cr). The selection criterion on which radionuclide should be used, in modern clinics, depends on which joints are to be treated. Thus, the smaller the joint, the lowest should be the energy of the beta emitted and the penetration in soft tissue of these particles. This leads to the use of fixed radionuclides and doses for each kind of joint. In the Isotopes Centre, we've been carrying on studies for the development of radiopharmaceuticals for the radiosynoviortheses treatment and focused our attention in the following radionuclides: 32 P, 90 Y, 188 Re, 177 Lu, 51 Cr, 153 Sm and 169 Er. The main objective of this paper was to obtain the absorbed dose profiles for radionuclides of frequent or potential use in radiosynoviortheses. These profiles reveal the absorbed dose imparted per unit activity of injected radionuclide (Gy/h*MBq) in the synovial membrane and the articular cartilage. The researched radionuclides were those previously mentioned. Also were calculated the therapeutic range of each radionuclides in synovial tissue. The therapeutic range is defined as the deepness at which the absorbed dose equals the 10 % of the maximum dose deposited in the synovial surface. This range determines the synovial thickness that can be sufficiently irradiated and thus successfully treated. The synovial membrane model consisted on a cylinder with the source uniformly distributed in its volume. This

Synergistic extraction and separation of yttrium from heavy rare earths using mixture of sec-octylphenoxy acetic acid and bis(2,4,4-trimethylpentyl)phosphinic acid

International Nuclear Information System (INIS)

Sun Xiaobo; Zhao Junmei; Meng Shulan; Li Deqian

2005-01-01

Synergistic extraction and separation of yttrium (Y) from heavy rare earths (HRE) in chloride medium using mixture of sec-octylphenoxy acetic acid (CA-12, HA) and bis(2,4,4-trimethylpentyl)phosphinic acid (Cyanex272, HL) in n-heptane has been investigated. The synergistic enhancement coefficients, R max , were obtained for Ho 3+ (5.12), Y 3+ (5.34), Er 3+ (7.04), Tm 3+ (7.50), Yb 3+ (13.12) and Lu 3+ (17.58). The separation factors (SF) between Y 3+ and HRE were obtained, and it was found that Er 3+ would form the new complex as ErH 6 A 4 L 5 in the mixture system. A cation exchange mechanism was proposed. The equilibrium constant, formation constant and thermodynamic parameters such as ΔG = -18.48 kJ/mol, ΔH = -1.36 kJ/mol and ΔS = 0.058 kJ/mol were determined. The CA-12 and Cyanex272 mixture system showed higher extraction efficiency, larger separation factors as well as excellent stripping behaviors. The application potential of the mixture system to separate Y from HRE has been discussed

Comparative study of optical and scintillation properties of YVO{sub 4}, (Lu{sub 0.5}Y{sub 0.5})VO{sub 4}, and LuVO{sub 4} single crystals

Energy Technology Data Exchange (ETDEWEB)

Fujimoto, Yutaka, E-mail: fuji-you@tagen.tohoku.ac.j [IMRAM, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577 (Japan); Yanagida, Takayuki; Yokota, Yuui; Chani, Valery [IMRAM, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577 (Japan); Kochurikhin, Vladimir V. [General Physics Institute, 38 Vavilov Street, 119991, Federation, Moscow (Russian Federation); Yoshikawa, Akira [IMRAM, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577 (Japan); NICHe, Tohoku University, 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai 980-8579 (Japan)

2011-04-11

Optical and scintillation properties of YVO{sub 4}, (Lu{sub 0.5}Y{sub 0.5})VO{sub 4}, and LuVO{sub 4} single crystals grown by the Czochralski (CZ) method with RF heating system are compared. All vanadate crystals show high transmittance ({approx}80%) in the 400-900 nm wavelength range. In both photo- and radio-luminescence spectra, intense peak around 400-500 nm, which was ascribed to the transition from triplet state of VO{sub 4}{sup 3-}, was clearly observed. The main decay time component was about 38 {mu}s (YVO{sub 4}), 18 {mu}s ((Lu{sub 0.5}Y{sub 0.5})VO{sub 4}), and 17 {mu}s (LuVO{sub 4}) under 340 nm excitation. The scintillation light yields of YVO{sub 4}, (Lu{sub 0.5}Y{sub 0.5})VO{sub 4}, and LuVO{sub 4} crystals (obtained from the {sup 137}Cs excited pulse height spectra) were evaluated to be about 11,200, 10,700, and 10,300 ph/MeV, respectively.

177Lu-DOTA-Bevacizumab: Radioimmunotherapy Agent for Melanoma.

Science.gov (United States)

Camacho, Ximena; Calzada, Victoria; Fernandez, Marcelo; Alonso, Omar; Chammas, Roger; Riva, Eloisa; Gambini, Juan Pablo; Cabral, Pablo

2017-01-01

Vascular endothelial growth factor (VEGF) is one of the classic factors to tumor-induced angiogenesis in several types, including melanoma. Bevacizumab is a humanized monoclonal antibody directed against VEGF. To radiolabel Bevacizumab with 177-Lutetium as a potential radioimmunotherapy agent for melanoma. Bevacizumab was derivatized with DOTA-NHS-ester at 4 ºC for 18 h. DOTABevacizumab was radiolabeled with 177LuCl3 (15 MBq/mg) at 37 ºC for 1 h. The studies were performed in healthy and B16F1 tumor-bearing C57BL/6J mice at 24 and 48 h (n = 5). Scinthigraphic imaging studies were performed at 24 h to determine the radiochemical stability, targeting specificity and pharmacokinetics of the 177Lutetium-labeled antibody. DOTA-Bevacizumab was efficiently labeled with 177LuCl3 at 37 °C. The in-vitro stability of labeled product was optimal over 72 h. In-vivo biodistribution studies showed a high liver and tumor uptake of 177Lu-DOTA-Bevacizumab, with tumor-to-muscle ratios of 11.58 and 6.37 at 24 and 48 h p.i. Scintigraphic imaging of melanoma tumor-bearing C57BL/6J mice showed liver and a high tumor selective uptake of 177Lu-DOTA-Bevacizumab at 24 h. Our results support the potential role of 177Lu-DOTA-Bevacizumab as a novel radioimmunotherapy agent for melanoma. We hope that these novel molecular imaging agents will open the path to new diagnostic and therapeutic strategies for Melanoma disease. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Green and red luminescence in co-precipitation synthesized Pr:LuAG nanophosphor

Energy Technology Data Exchange (ETDEWEB)

Kumar, S. Arun; Kumar, K. Ashok; Gunaseelan, M.; Senthilselvan, J., E-mail: jsselvan@hotmail.com [Department of Nuclear Physics, University of Madras, Guindy Campus, Chennai–600 025, Tamil Nadu (India); Asokan, K. [Materials Science Group, Inter University Accelerator Centre, New Delhi-110067 (India)

2016-05-06

Pr:LuAG nanophosphor is an effective candidate in magnetic resonance imaging coupled positron emission tomography (MRI-PET) for medical imaging and scintillator applications. LuAG:Pr (0.05, 0.15 mol%) nanoscale ceramic powders were synthesized by co-precipitation method using urea as precipitant. Effect of antisite defect on structure and luminescence behavior was investigated. Pr:LuAG nanoceramic powders are found crystallized in cubic structure by high temperature calcination at 1400 °C and it shows antisite defect. HR-SEM analysis revealed spherically shaped Pr:LuAG nanoceramic particulate powders with ∼100 nm size. By the excitation at 450 nm, Pr:LuAG nanophosphor exhibit green to red luminescence in the wavelength range of 520 to 680 nm, which is originated from multiplet transition of Pr{sup 3+} ions.

Symmetry-Breaking Transitions in RECuAs_2-xP_x (RE=Sm, Gd, Ho, and Er)

Energy Technology Data Exchange (ETDEWEB)

Mozharivskyj, Yurij [Iowa State Univ., Ames, IA (United States)

2002-01-01

Structural changes resulting in lower symmetries can be understood in terms of electronic instabilities and Coulomb interactions. The interplay of these two interrelated factors is complicated and difficult to analyze. The RECuAs_2-xP _x phases, because of the variation in the chemical content (As/P substitution), allow, with the aid of band structures, Madelung energies and Landau theory, a partial unraveling of the forces important in the symmetry-breaking transitions in RECuAs_2-xP _x (RE = Sm, Gd, Ho and Er). Distortions of the P layers in SmCu_1.15P₂, GdCuP_2.20 and ErCuP₂ are usefully thought of as generalized Peierls distortions, i.e., they lower the electronic (and total) energy and lead to more stable structures. On the other hand, the P4/nmm → Pmmn transitions, which are observed in all studied arsenophosphide series and occur upon substitution of P for As, originate from the B1g vibrational mode and are structural adaptations to smaller P atoms. These transitions provide tighter atomic packing and better Coulomb interactions. Configurational contribution to the entropy becomes important in stabilizing the mixed occupancy in the RECuAs _2-xP _x arsenophosphides. While geometric and electronic factors favor separation of the As and P atoms over two different crystallographic sites, configurational entropy stabilizes the As/P mixing on these two sites.;Progress in the research on RECuAs_2-xP _x was dependent upon the ability of Landau theory to predict, explain and dismiss structural models and transitions. The space group Pmmn (arising from the B 1g vibrational mode) in all mixed arsenophosphides and the existence of these mixed arsenophosphides followed from the analysis of GdCuAs ₂ and GdCuP₂, using Landau theory. The impossibility of obtaining the high-symmetry structure (P4/nmm) and the low symmetry structure

The Novohrad Museum and Gallery in Lučenec past and present (História a súčasnosť Novohradského múzea a galérie v Lučenci

Directory of Open Access Journals (Sweden)

Michaela Škodová

2016-09-01

Full Text Available The Novohrad Museum and Gallery in Lučenec specializes in the regional history of enamel- and glass-making and visual arts. It holds a collection of over 30,000 art, archeo-logical, historical and ethnological objects. Since 1983, the musem and gallery have been a host to the annual Acquarelle Triennale and since 1989, it has hosted the oldest symposium of its kind in Slovakia, the International Ceramic Symposium, which showcases the contemporary ceramic production in Slovakia. This paper outlines the history of the museum and its focus, concentrating on the work done in the last decade.

Progress in the development of LuAlO3 based scintillators

CERN Document Server

Belsky, A; Lecoq, P; Dujardin, C; Garnier, N; Canibano, H; Pédrini, C; Petrosian, A

2000-01-01

LuAlO3:Ce3+ (LuAP) and LuxY1-xAlO3:Ce3+ (LuYAP) crystals are the promote scintillation materials for Positron Emission Tomography. Actual study of these scintillators develops in the tree directions: (i) growth of large size LuAP crystals with stable properties, (ii) relationship between composition of LuYAP crystals and scintillation properties, and (iii) scintillation mechanisms in lutetium compounds. After improving of growth conditions a large size samples (length greater than 40 mm) have been prepared. Crystals show a good correlation between growth parameters, light yield and transmission spectra. We performed a series of samples with calibrated size (2x2x10 mm3) and compare the light yield with a standard BGO and LSO samples. Mixed crystals with composition of 0.6 less than x less than 0.8 show a significant increase of light yield. We suggest that the short order clusterisation in mixed crystals may by playing an important role in governing the scintillation efficiency. In order to clarify the scintil...

Preparation of .sup.166./sup.Ho-Macroaggregates and .sup.166./sup.Ho-Chitosan for the Radiotherapy

Czech Academy of Sciences Publication Activity Database

Kropáček, Martin; Melichar, František; Mirzajevová, Marcela

2002-01-01

Roč. 29, č. 2 (2002), s. 382 ISSN 1619-7070 R&D Projects: GA MZd NM6828; GA AV ČR KSK4055109 Keywords : Holmium-166 * 166 Ho-macroaggregates * 166 Ho-chitosan Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders

Correlating states across isomers in 152Ho isotope

International Nuclear Information System (INIS)

Pramanik, Dibyadyuti; Dey, G.; Sarkar, S.; Bisoi, A.; Ray, S.; Kshetri, R.; Ray, I.; Pradhan, M.K.; Goswami, A.; Banerjee, P.; Mukherjee, A.; Bhattacharya, S.; Saha Sarkar, M.; Chakraborty, A.; Krishichayan; Ganguly, S.; Ray Basu, M.; Ganguly, G.; Raut, R.; Ghugre, S.S.; Sinha, A.K.; Basu, S.K.

2011-01-01

The odd-odd 152 Ho (N = 85) is a very interesting candidate for investigation of interplay of single - particle oblate states and prolate collective states, because it is situated between the N=82 shell closure and the strongly collective N > 87 region. It has been shown that there is a possibility of shape coexistence even at lower spins in 153 Ho. The structural evolution of Ho isotopes from A = 151 to 154 has also been studied. The features observed have been interpreted theoretically using shell model as well as Total Routhian surface calculations. Results have been combined with that for 153 Ho to study the evolution of structural features in these Ho isotopes with increasing neutron numbers and increasing spin. In the present work, experimental data on 152 Ho have been analysed to connect the three groups of transitions and confirm the possibility of a fourth isomer in the excitation spectrum

Optimization of LSO/LuYAP phoswich detector for small animal PET

International Nuclear Information System (INIS)

Jung, Jin Ho; Choi, Yong; Chung, Yong Hyun; Devroede, Olivier; Krieguer, Magalie; Bruyndonckx, Peter; Tavernier, Stefaan

2007-01-01

LSO/LuYAP phoswich detectors for small animal PET were developed to measure the depth of interaction (DOI), and to improve the spatial resolution at the edge of the field of view (FOV). The aim of this study was to optimize the optical coupling conditions between the crystal and photomultiplier tube (PMT) to maximize the light-collection efficiency, and to develop a method for rejecting scatter events by applying an equal energy window in each crystal layer. The light yields of the phoswich detector were estimated by changing the refractive index of the optical coupling material using a DETECT simulation. The accuracy of the DOI measurement on the phoswich detector, using an optical coupling material with the optimal light yield, were evaluated experimentally and compared with the air condition. The energy window for the photopeak events cannot be applied properly because the light outputs of LSO and LuYAP are different. The LSO/LuYAP photopeaks need to be superposed in order to effectively discriminate the scattered events by applying an equal energy window. The photopeaks of the LSO and LuYAP can be superposed by inserting a reflecting material between the crystals. The optimal coverage ratio of the inserting material was derived from a DETECT simulation, and its performance was investigated. In the simulation result, optimal refractive index of the optical coupling material was 1.7. The average DOI measurement errors of the LSO/LuYAP were 0.6%/3.4% and 4.9%/41.4% in the phoswich detector with and without an optical coupling material, respectively. The photopeaks of the LSO and LuYAP were superposed by covering 75% of the contact surface between the crystals with white Teflon. The DOI measurement errors of the LSO/LuYAP were 0.2%/2.4%. In this study, the optimal condition of the optical coupling material inserted between the crystal and PMT was derived to improve the accuracy of DOI measurement, and a photopeak superposition method of the LSO and LuYAP was

Surface magnetic phase transitions in Dy/Lu superlattices

International Nuclear Information System (INIS)

Goff, J.P.; Sarthour, R.S.; Micheletti, C.; Langridge, S.; Wilkins, C.J.T.; Ward, R.C.C.; Wells, M.R.

1999-01-01

Dy/Lu superlattices comprising ferromagnetic Dy blocks coupled antiferromagnetically across the Lu blocks may be modelled as a chain of XY spins with antiferromagnetic exchange and six-fold anisotropy. We have calculated the stable magnetic phases for the cases of large anisotropy and a field applied along an easy direction. For an infinite chain an intermediate phase (1, 5,...) is predicted, where the notation gives the angle between the moment and the applied field in units of π/3. Furthermore, the effects of surface reconstruction are determined for finite chains. A [Dy 20 Lu 12 ] 20 superlattice has been studied using bulk magnetization and polarized neutron reflectivity. The (1, 5,...) phase has been identified and the results provide direct evidence in support of the theoretical predictions. Dipolar forces are shown to account for the magnitude of the observed exchange coupling. (Copyright (c) 1999 Elsevier Science B.V., Amsterdam. All rights reserved.)

Optical characteristics of BaGa2S4:Ho3+ and BaGa2Se4:Ho3+ single crystals

International Nuclear Information System (INIS)

Choe, Sung-Hyu; Jin, Moon-Seog; Kim, Wha-Tek

2005-01-01

BaGa 2 S 4 , BaGa 2 S 4 :Ho 3+ , BaGa 2 Se 4 , and BaGa 2 Se 4 :Ho 3+ single crystals were grown by using the chemical transport reaction method. The optical energy gaps of the single crystals were investigated in the temperature region from 11 K to 300 K. The temperature dependence of the optical energy gap was well fitted by the Varshni equation. Two broad emission bands were observed in the photoluminescence spectra of the single crystals. These bands were attributed to donor-acceptor pair recombinations. Sharp emission peaks were observed in the BaGa 2 S 4 :Ho 3+ and the BaGa 2 Se 4 :Ho 3+ single crystals and were assigned to radiation recombination between split Stark levels of Ho 3+ .

Embedding of $^{163}$Ho and $^{166m}$ Ho in the energy absorbers of low temperature metallic magnetic calorimeters

CERN Multimedia

The calorimetric measurement of the $^{163}$Ho electron capture spectrum is a promising tool to investigate the electron neutrino mass. A suitable method to embed the source in the detectors is the ion-implantation. This process has already been used to embed $^{163}$Ho ions in micro-fabricated low temperature metallic magnetic prototypes. The $^{163}$Ho electron capture spectrum obtained with these first prototypes is presently the most precise with an energy resolution of $\\Delta$$\\textit{E}$$_{FWHM}$ = 7.6 eV. In order to test the performance of the new generation of low temperature metallic magnetic calorimeters, we propose to perform a $^{163}$Ho ion-implantation on the new chip having two arrays consisting of 32 pixels each. An activity of about 1 Bq per pixel is required. With this new detector array we will be able to achieve a better energy resolution and to acquire a higher statistics which allows for studying the $^{163}$Ho spectral shape. We propose also to perform an ion-implantation of $^{166m}$...

Evidence for inelastic neutron acceleration by the 177Lu isomer

International Nuclear Information System (INIS)

Roig, O.; Belier, G.; Meot, V.; Daugas, J.-M.; Abt, D.; Aupiais, J.; Jutier, Ch.; Petit, G. Le; Letourneau, A.; Marie, F.; Veyssiere, Ch.

2006-01-01

The neutron burnup cross section σ burnup m on the long-lived metastable state of 177 Lu has been measured from a specially designed isomeric target. The Maxwellian averaged cross section obtained for this reaction on 177 Lu m (J π =23/2 - ) is σ burnup m =626±45 b at the reactor temperature T=323 K. The difference between the burnup cross section and the previously measured capture cross section σ n,γ clearly shows a possible existence of 177 Lu m deexcitation via (n,n ' ) inelastic neutron acceleration channels. The results are interpreted in terms of a statistical approach using parameters from a deformed optical potential calculation

Preparation of 177Lu-DOTA/DTPA-Bz-Cys-RGD dimer and biodistribution evaluation in normal mice

International Nuclear Information System (INIS)

Sheng Feng; Jia Bing; Wang Fan; He Weiwei; Liu Zhaofei; Zhao Huiyun

2008-01-01

177 Lu-DOTA-Bz-Cys-RGD dimer and 177 Lu-DTPA-Bz-Cys-RGD dimer were prepared, and the in vitro and in vivo properties were compared. TLC and HPLC show that the labeling yields of two radiolabeled compounds are more than 95% under optimal conditions (pH=5.0, reacting at 100 degree C for 15-20 min), and the two radiolabeled compounds show pretty good in vitro stability. HPLC analyses and lg P values reveal that lipophilicity of 177 Lu-DOTA-Bz-Cys- RGD dimer is higher than 177 Lu-DTPA-Bz-Cys-RGD dimer. The uptake of 177 Lu-DTPA-Bz-Cys- RGD dimer in other tissues is significantly higher than that of 177 Lu-DOTA-Bz-Cys-RGD dimer at 4 h postinjection, except for blood and spleen. The in vivo stability of 177 Lu-DOTA-Bz-Cys-RGD dimer is much better than 177 Lu-DTPA-Bz-Cys-RGD dimer. Bz-DOTA is an ideal bifunctional chelator for 177 Lu labeling of RGD dimer. (authors)

Targeting angiogenesis for radioimmunotherapy with a {sup 177}Lu-labeled antibody

Energy Technology Data Exchange (ETDEWEB)

Ehlerding, Emily B.; Hernandez, Reinier [University of Wisconsin - Madison, Department of Medical Physics, Madison, WI (United States); Lacognata, Saige; Jiang, Dawei [University of Wisconsin - Madison, Department of Radiology, Madison, WI (United States); Ferreira, Carolina A. [University of Wisconsin - Madison, Department of Biomedical Engineering, Madison, WI (United States); Goel, Shreya [University of Wisconsin - Madison, Department of Materials Science and Engineering, Madison, WI (United States); Jeffery, Justin J. [University of Wisconsin - Madison, Small Animal Imaging Facility, Madison, WI (United States); Theuer, Charles P. [TRACON Pharmaceuticals, Inc., San Diego, CA (United States); Cai, Weibo [University of Wisconsin - Madison, Department of Medical Physics, Madison, WI (United States); University of Wisconsin - Madison, Department of Radiology, Madison, WI (United States); University of Wisconsin - Madison, Department of Biomedical Engineering, Madison, WI (United States); University of Wisconsin - Madison, Department of Materials Science and Engineering, Madison, WI (United States)

2018-01-15

Increased angiogenesis is a marker of aggressiveness in many cancers. Targeted radionuclide therapy of these cancers with angiogenesis-targeting agents may curtail this increased blood vessel formation and slow the growth of tumors, both primary and metastatic. CD105, or endoglin, has a primary role in angiogenesis in a number of cancers, making this a widely applicable target for targeted radioimmunotherapy. The anti-CD105 antibody, TRC105 (TRACON Pharmaceuticals), was conjugated with DTPA for radiolabeling with {sup 177}Lu (t{sub 1/2} 6.65 days). Balb/c mice were implanted with 4T1 mammary carcinoma cells, and five study groups were used: {sup 177}Lu only, TRC105 only, {sup 177}Lu-DTPA-IgG (a nonspecific antibody), {sup 177}Lu-DTPA-TRC105 low-dose, and {sup 177}Lu-DTPA-TRC105 high-dose. Toxicity of the agent was monitored by body weight measurements and analysis of blood markers. Biodistribution studies of {sup 177}Lu-DTPA-TRC105 were also performed at 1 and 7 days after injection. Ex vivo histology studies of various tissues were conducted at 1, 7, and 30 days after injection of high-dose {sup 177}Lu-DTPA-TRC105. Biodistribution studies indicated steady uptake of {sup 177}Lu-DTPA-TRC105 in 4T1 tumors between 1 and 7 days after injection (14.3 ± 2.3%ID/g and 11.6 ± 6.1%ID/g, respectively; n = 3) and gradual clearance from other organs. Significant inhibition of tumor growth was observed in the high-dose group, with a corresponding significant increase in survival (p < 0.001, all groups). In most study groups (all except the nonspecific IgG group), the body weights of the mice did not decrease by more than 10%, indicating the safety of the injected agents. Serum alanine transaminase levels remained nearly constant indicating no damage to the liver (a primary clearance organ of the agent), and this was confirmed by ex vivo histological analyses. {sup 177}Lu-DTPA-TRC105, when administered at a sufficient dose, is able to curtail tumor growth and provide a

A routine high-precision method for Lu-Hf isotope geochemistry and chronology

Science.gov (United States)

Patchett, P.J.; Tatsumoto, M.

1981-01-01

A method for chemical separation of Lu and Hf from rock, meteorite and mineral samples is described, together with a much improved mass spectrometric running technique for Hf. This allows (i) geo- and cosmochronology using the176Lu???176Hf+??- decay scheme, and (ii) geochemical studies of planetary processes in the earth and moon. Chemical yields for the three-stage ion-exchange column procedure average 90% for Hf. Chemical blanks are international mass spectrometric standard; suitable aliquots, prepared from a single batch of JMC 475, are available from Denver. Lu-Hf analyses of the standard rocks BCR-1 and JB-1 are given. The potential of the Lu-Hf method in isotope geochemistry is assessed. ?? 1980 Springer-Verlag.

Comparative vectorial efficiency of Lutzomyia evansi and Lu. longipalpis for transmitting Leishmania chagasi.

Science.gov (United States)

Montoya-Lerma, J; Cadena, H; Oviedo, M; Ready, P D; Barazarte, R; Travi, B L; Lane, R P

2003-01-01

The infection rates and development of Leishmania chagasi in two sandfly species, Lutzomyia evansi and Lutzomyia longipalpis, were evaluated under natural and experimental conditions. Natural infection rates of Lu. evansi in San Andrés de Sotavento (Colombia) and Montañas de Peraza (Venezuela) (0.05 and 0.2%, respectively) were similar to those previously recorded for this species in Colombia and Venezuela and for Lu. longipalpis in many foci of American Visceral Leishmaniasis (AVL). Both sand fly species were able to support the development of two Colombian strains of L. chagasi experimentally acquired from dogs, hamsters or membrane feeders. However, the experimental infection rates and the sequence of parasite development in the guts of these sand flies revealed that parasite colonisation, differentiation, migration and attachment were more frequent and uniform in Lu. longipalpis than in Lu. evansi. This is consistent with a more recent association between L. chagasi and Lu. evansi, and these results might help to explain the irregularity of AVL outbreaks in foci where Lu. evansi has been reported as the sole vector. Copyright 2002 Elsevier Science B.V.

Peptide receptor radionuclide therapy (PRRT) using Lu-177 DOTA-NOC and Lu-177 DOTA-TATE: Comparative results

International Nuclear Information System (INIS)

Wehrmann, C.; Senftleben, S.; Baum, R.P.

2007-01-01

Full text: Aim: One of the few treatment options for inoperable neuroendocrine tumors (NET) is peptide receptor radiotherapy with somatostatin analogues. DOTA-NOC shows the highest affinity to the somatostatin receptors (sstr) 3 and 5 and a very high affinity to sstr 2. We compared the dosimetric parameters uptake, half-life (kinetics) and mean absorbed organ and tumor doses of 177 Lu DOTANOC and 177 Lu DOTA-TATE. Methods: 139 patients with neuroendocrine tumors with high sstr expression (verified by Ga-68 DOTA-NOC PET/CT) were studied. 130 patients (57m, 73f; aged 60±11a) were treated with 2.5-7.4 GBq Lu-177 DOTA-TATE and 9 patients (3m, 6f, aged 64±10a) with 3.6-7.4 GBq Lu-177 DOTA-NOC. Whole-body scans were performed after 0.5h, 3h, 24h, 48h, 72h and 96h p.i. Blood samples from 23 patients were obtained after therapy. By means of geometric mean and after background correction, ROI results were used to calculate the estimated absorbed organ and tumor doses according to the MIRD-scheme (OLINDA software). Results: Lu-177 DOTA-NOC showed a higher uptake as compared to Lu-177 DOTATATE (=100%): for whole-body about 38% and in normal tissue 36%, in the spleen 17% and in the kidneys 18%. The tumor uptake was about 5% higher for DOTA-TATE. The effective half-life for whole-body was comparable for both peptides (t1/2a NOC 2.9h vs. TATE 2.4h and t1/2b NOC 54h vs. TATE 56h). In normal tissue, t1/2a was similar (NOC 3.3h; TATE 2.6h) but the t1/2b was longer for DOTA-TATE (NOC 43h; TATE 48h). t1/2b was longer for DOTA-NOC in the spleen (NOC 81h; TATE 72h) and in the kidney (NOC 68.1h; TATE 65h). The mean absorbed dose in the kidney (TATE 5Sv; NOC 6Sv) and spleen (TATE 7Sv; NOC 8Sv) was higher for DOTA-NOC. In the tumor, the t1/2b was higher for DOTA-TATE (NOC 65h; TATE 77h). For DOTA-TATE the whole-body dose was lower (0.27Sv) as compared to DOTA-NOC (0.38 Sv) (significant by unpaired sign test). The estimated mean absorbed tumor doses were 47+/-66 Sv for DOTA-TATE and 35

The electron capture in 163Ho experiment - ECHo

Science.gov (United States)

Gastaldo, L.; Blaum, K.; Chrysalidis, K.; Day Goodacre, T.; Domula, A.; Door, M.; Dorrer, H.; Düllmann, Ch. E.; Eberhardt, K.; Eliseev, S.; Enss, C.; Faessler, A.; Filianin, P.; Fleischmann, A.; Fonnesu, D.; Gamer, L.; Haas, R.; Hassel, C.; Hengstler, D.; Jochum, J.; Johnston, K.; Kebschull, U.; Kempf, S.; Kieck, T.; Köster, U.; Lahiri, S.; Maiti, M.; Mantegazzini, F.; Marsh, B.; Neroutsos, P.; Novikov, Yu. N.; Ranitzsch, P. C. O.; Rothe, S.; Rischka, A.; Saenz, A.; Sander, O.; Schneider, F.; Scholl, S.; Schüssler, R. X.; Schweiger, Ch.; Simkovic, F.; Stora, T.; Szücs, Z.; Türler, A.; Veinhard, M.; Weber, M.; Wegner, M.; Wendt, K.; Zuber, K.

2017-06-01

Neutrinos, and in particular their tiny but non-vanishing masses, can be considered one of the doors towards physics beyond the Standard Model. Precision measurements of the kinematics of weak interactions, in particular of the 3H β-decay and the 163Ho electron capture (EC), represent the only model independent approach to determine the absolute scale of neutrino masses. The electron capture in 163Ho experiment, ECHo, is designed to reach sub-eV sensitivity on the electron neutrino mass by means of the analysis of the calorimetrically measured electron capture spectrum of the nuclide 163Ho. The maximum energy available for this decay, about 2.8 keV, constrains the type of detectors that can be used. Arrays of low temperature metallic magnetic calorimeters (MMCs) are being developed to measure the 163Ho EC spectrum with energy resolution below 3 eV FWHM and with a time resolution below 1 μs. To achieve the sub-eV sensitivity on the electron neutrino mass, together with the detector optimization, the availability of large ultra-pure 163Ho samples, the identification and suppression of background sources as well as the precise parametrization of the 163Ho EC spectrum are of utmost importance. The high-energy resolution 163Ho spectra measured with the first MMC prototypes with ion-implanted 163Ho set the basis for the ECHo experiment. We describe the conceptual design of ECHo and motivate the strategies we have adopted to carry on the present medium scale experiment, ECHo-1K. In this experiment, the use of 1 kBq 163Ho will allow to reach a neutrino mass sensitivity below 10 eV/ c 2. We then discuss how the results being achieved in ECHo-1k will guide the design of the next stage of the ECHo experiment, ECHo-1M, where a source of the order of 1 MBq 163Ho embedded in large MMCs arrays will allow to reach sub-eV sensitivity on the electron neutrino mass.

Development of a therapeutic radiopharmaceutical {sup 177}Lu-DOTA- Minigastrin for potential use in PRRT; Desarrollo de un radiofarmaco terapeutico {sup 177}Lu-DOTA-Minigastrina para su potencial uso en PRRT

Energy Technology Data Exchange (ETDEWEB)

Lopez Bularte, A. C.; Nevares, N. N.; Zapata, A. M.; Perez, J. H.; Crudo, J. L. [Comision Nacional de Energia Atomica (Argentina); Puerta Yepes, N.; Rojo, A. M. [Autoridad Regulatoria Nuclear (Argentina)

2010-07-01

The aim of this work is to obtain {sup 177}Lu-DOTA-Minigastrin with high radiochemical purity (RP) and the highest specific activity (Ae) as possible, using a locally produced (Nuclear Reactor RA-3, Ezeiza Atomic Center) {sup 177}LuCl{sub 3} of an intermediate level of Ae (between 6.36 to 17.95 Ci/mg of {sup 176}Lu) ) and also to perform in vitro and in vivo stability tests, dose calculation in normal mice and its extrapolation to a human model. (authors) [Spanish] El objetivo de este trabajo consistio en obtener {sup 177}Lu-DOTA-Minigastrina con una alta pureza radioquimica (PR) y la mayor actividad especifica (Ae) posible, empleando {sup 177}LuCl{sub 3} de media Ae (entre 6,36-17,95 Ci/mg de {sup 176}Lu) de produccion local (Reactor Nuclear RA-3, Centro Atomico Ezeiza), y realizar los ensayos de estabilidad in vitro e in vivo, el calculo de dosis en ratones normales y su extrapolacion a un modelo humano. (autores)

Heavy rare earth elements affect early life stages in Paracentrotus lividus and Arbacia lixula sea urchins

International Nuclear Information System (INIS)

Oral, Rahime; Pagano, Giovanni; Siciliano, Antonietta; Gravina, Maria; Palumbo, Anna; Castellano, Immacolata; Migliaccio, Oriana; Thomas, Philippe J.; Guida, Marco; Tommasi, Franca; Trifuoggi, Marco

2017-01-01

Background: Heavy rare earth elements (HREEs) have been scarcely studied for their toxicity, in spite of their applications in several technologies. Thus HREEs require timely investigations for their adverse health effects. Methods: Paracentrotus lividus and Arbacia lixula embryos and sperm were exposed to trichloride salts of five HREEs (Dy, Ho, Er, Yb and Lu) and to Ce(III) as a light REE (LREE) reference to evaluate: 1) developmental defects (% DD) in HREE-exposed larvae or in the offspring of HREE-exposed sperm; 2) mitotic anomalies; 3) fertilization success; and 4) reactive oxygen species (ROS) formation, and nitric oxide (NO) and malondialdehyde (MDA) levels. Nominal HREE concentrations were confirmed by inductively coupled plasma mass spectrometry (ICP-MS). Results: HREEs induced concentration-related DD increases in P. lividus and A. lixula larvae, ranging from no significant DD increase at 10 −7 M HREEs up to ≅100% DD at 10 −5 M HREE. Larvae exposed to 10 −5 M Ce(III) resulted in less severe DD rates compared to HREEs. Decreased mitotic activity and increased aberration rates were found in HREE-exposed P. lividus embryos. Significant increases in ROS formation and NO levels were found both in HREE-exposed and in Ce(III) embryos, whereas only Ce(III), but not HREEs resulted in significant increase in MDA levels. Sperm exposure to HREEs (10 −5 –10 −4 M) resulted in a concentration-related decrease in fertilization success along with increase in offspring damage. These effects were significantly enhanced for Dy(III), Ho(III), Er(III) and Yb(III), compared to Lu(III) and to Ce(III). Conclusion: HREE-associated toxicity affected embryogenesis, fertilization, cytogenetic and redox endpoints showing different toxicities of tested HREEs. - Highlights: • Different toxicities were exerted by five tested HREEs on sea urchin early life stages. • Sea urchin embryos and sperm were sensitive to HREE levels ranging from 1 to 100 μM, according to

Thermodynamic assessments of the Ag-Er and Er-Y systems

International Nuclear Information System (INIS)

Wang, S.L.; Wang, C.P.; Liu, X.J.; Tang, A.T.; Pan, F.S.; Ishida, K.

2010-01-01

The phase diagrams and thermodynamic properties in the Ag-Er and Er-Y binary systems have been assessed by using the CALPHAD (Calculation of Phase Diagrams) method on the basis of the experimental data including the thermodynamic properties and phase equilibria. The Gibbs free energies of the liquid, bcc, fcc, and hcp phases were described by the subregular solution model with the Redlich-Kister equation, and those of intermetallic compounds (Ag 2 Er and AgEr phases) were treated as stoichiometric compounds, and Ag 51 Er 14 phase was modeled by the sublattice model in the Ag-Er binary system. The thermodynamic parameters of the Ag-Er and Er-Y binary systems were obtained, and an agreement between the calculated results and experimental data was obtained for each binary system.

Magnetic state controllable critical temperature in epitaxial Ho/Nb bilayers

Directory of Open Access Journals (Sweden)

Yuanzhou Gu

2014-04-01

Full Text Available We study the magnetic properties of Ho thin films with different crystallinity (either epitaxial or non-epitaxial and investigate their proximity effects with Nb thin films. Magnetic measurements show that epitaxial Ho has large anisotropy in two different crystal directions in contrast to non-epitaxial Ho. Transport measurements show that the superconducting transition temperature (Tc of Nb thin films can be significantly suppressed at zero field by epitaxial Ho compared with non-epitaxial Ho. We also demonstrate a direct control over Tc by changing the magnetic states of the epitaxial Ho layer, and attribute the strong proximity effects to exchange interaction.

Holmium laser lithotripsy (HoLL) of ureteral calculi

Science.gov (United States)

Kuntz, Rainer M.; Lehrich, Karin; Fayad, Amr

2001-05-01

The effectiveness and side effects of ureteroscopic HoLL of ureteral stones should be evaluated. In 63 patients (17 female, 46 males) a total of 75 stones of 3-20 mm diameter were treated with ureteroscopic HoLL. 18.7 percent of stones were located in the proximal third, 24.0 percent in the middle third and 57.3 percent in the distal third of the ureter. HoLL was performed with small diameter semirigid and flexible ureteroscopes, 220 or 365 nm flexible laser fibers and a holmium:YAG laser at a power of 5-15 W (0.5-1.0 J, 10- 15 Hz). 47 of 63 patients (74.6 percent) were immediately free of stones, and 8 others (12.6 percent) lost their residual fragments spontaneously within two weeks. Another 2 patients received additional chmolitholysis for uric acid stone fragments, i.e. 90.5 percent of patients were stone free by one sitting of ureterscopic HoLL. Of the remaining 6 patients (9.5 percent) who still had residual calculi 4 weeks after HoLL, 2 asymptomatic patients refused any additional treatment, 2 patients preferred treatment with ESWL, and 2 patients had a successful second HoLL, thereby raising the success rate of ureteroscopic HoLL to 93.7 percent. 2 patients showed contrast medium extravasation on retrograde ureterograms, due to guide wire perforation. No ureteral stricture occurred. In conclusion, transurethral ureteroscopic HoLL proved to be a safe and successful minimal invasive treatment of ureteral calculi.

Scintillation properties of a La, Lu-admix gadolinium pyrosilicate crystal

Energy Technology Data Exchange (ETDEWEB)

Kurosawa, Shunsuke, E-mail: kurosawa@imr.tohoku.ac.jp [Institute for Materials Research (IMR), Tohoku University 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); New Industry Creation Hatchery Center (NICHe) 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); Shishido, Toetsu; Suzuki, Akira; Sugawara, Takamasa; Nomura, Akiko; Yubuta, Kunio [Institute for Materials Research (IMR), Tohoku University 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Shoji, Yasuhiro [Institute for Materials Research (IMR), Tohoku University 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); C& A Corporation, 6-6-40 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Yokota, Yuui [New Industry Creation Hatchery Center (NICHe) 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); Pejchal, Jan [New Industry Creation Hatchery Center (NICHe) 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); Institute of Physics, AS CR, Cukrovarnická 10, 162 53 Prague (Czech Republic); Ohashi, Yuji [Institute for Materials Research (IMR), Tohoku University 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Kamada, Kei [New Industry Creation Hatchery Center (NICHe) 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); C& A Corporation, 6-6-40 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Yoshikawa, Akira [Institute for Materials Research (IMR), Tohoku University 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); New Industry Creation Hatchery Center (NICHe) 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); C& A Corporation, 6-6-40 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8577 (Japan)

2015-06-01

In order to obtain new scintillator with higher effective atomic number, a pyrosilicate crystal with a composition (Ce{sub 0.01}, Gd{sub 0.54}, La{sub 0.25}, Lu{sub 0.20}){sub 2}Si{sub 2}O{sub 7} (Ce:LaLu-GPS) was grown by the floating zone method. Emission wavelengths of this material were at 370 and 390 nm. Gamma-ray-excited pulse height and scintillation decay measurement showed that Ce:LaLu-GPS had a light output of 34,000±2000 photons/MeV, an FWHM energy resolution of 6.9±0.2%, and the decay time components of 59±1 ns (13%) and 570±20 ns (87%)

Novostavba rodinného domu

OpenAIRE

Manduch, Dávid

2017-01-01

Jedná sa o samostatne stojaci, dvojpodlažný, nepodpivničený rodinný dom zastrešený plochou vegetačnou strechou v obci Šalgovce. Súčasťou rodinného domu sú dve drevené terasy. Vstupná terasa sa nachádza pred hlavným vstupom do objektu a terasa pre relax je prístupná z obytnej miestnosti s kuchynským kútom. Z tejto terasy je priamy prístup do záhrady. Hlavný stavebný materiál rodinného domu sú stenové panely EcoCocon - kombinácia dreveného rámu a slamenej výplne Garáž je samostatne stojaci jedn...

Separation of heavier rare earths from neutron irradiated uranium targets

International Nuclear Information System (INIS)

Bhargava, V.K.; Rao, V.K.; Marathe, S.G.; Sahakundu, S.M.; Iyer, R.H.

1978-01-01

A radiochemical method is described for the separation of heavier rare earths from the fission of uranium. The method is particularly suitable for the separation of low yield (10sup(-5)%-10sup(-7)%), highly asymmetric rare earth fission products viz. sup(179,177)Lu, sup(175)Yb, sup(173)Tm, sup(172,171)Er, sup(167)Ho and sup(161,160)Tb in the neutron induced fission of natural and depleted uranium targets. Additional separation steps have been incorporated for decontamination from sup(239)Np (an activation product) and sup(93-90)Y (a high fission-yield product) which show similar chemical behaviour to rare earths. Separation of individual rare earths is achieved by a cation exchange method performed at 80 deg C by elution with α-hydroxyisobutyric acid (α-HIBA). (author)

Ternary oxide nanostructures and methods of making same

Science.gov (United States)

Wong, Stanislaus S [Stony Brook, NY; Park, Tae-Jin [Port Jefferson, NY

2009-09-08

A single crystalline ternary nanostructure having the formula A.sub.xB.sub.yO.sub.z, wherein x ranges from 0.25 to 24, and y ranges from 1.5 to 40, and wherein A and B are independently selected from the group consisting of Ag, Al, As, Au, B, Ba, Br, Ca, Cd, Ce, Cl, Cm, Co, Cr, Cs, Cu, Dy, Er, Eu, F, Fe, Ga, Gd, Ge, Hf, Ho, I, In, Ir, K, La, Li, Lu, Mg, Mn, Mo, Na, Nb, Nd, Ni, Os, P, Pb, Pd, Pr, Pt, Rb, Re, Rh, Ru, S, Sb, Sc, Se, Si, Sm, Sn, Sr, Ta, Tb, Tc, Te, Ti, Tl, Tm, U, V, W, Y, Yb, and Zn, wherein the nanostructure is at least 95% free of defects and/or dislocations.

Fabrication and characterization of intrinsic Josephson junctions in RE-123 whiskers

International Nuclear Information System (INIS)

Okutsu, T.; Ueda, S.; Ishii, S.; Nagasawa, M.; Takano, Y.

2008-01-01

The series of REBa 2 Cu 3 O 7-δ RE-123; RE = Y, Eu, Gd, Dy, Ho, Er, Tm, and Lu) single-crystal whiskers have been successfully grown using the Te- or Sb-doping method. Intrinsic Josephson junctions (IJJs) were fabricated from the whiskers using a focused ion beam (FIB). As-grown IJJs with T c > 70 K showed a Josephson current but no multi-branches in the current-voltage (I-V) characteristics. Under-doped specimens were obtained by a post-annealing process. As-grown IJJs with lower T c and all the specimens of the post-annealed IJJs showed clear multi-branched structure. The post-annealing reduced the critical temperature (T c ) and the critical current density (J c ) of the IJJs, and increased the anisotropic parameter γ

The impact of repeated cycles of radioligand therapy using [{sup 177}Lu]Lu-PSMA-617 on renal function in patients with hormone refractory metastatic prostate cancer

Energy Technology Data Exchange (ETDEWEB)

Yordanova, Anna; Becker, Anja; Eppard, Elisabeth; Kuerpig, Stefan; Essler, Markus; Ahmadzadehfar, Hojjat [University Hospital Bonn, Department of Nuclear Medicine, Bonn (Germany); Fisang, Christian [University Hospital Bonn, Department of Urology, Bonn (Germany); Feldmann, Georg [University Hospital Bonn, Department of Internal Medicine, MED3, Bonn (Germany)

2017-08-15

[{sup 177}Lu]Lu-PSMA-617 is a well-tolerated therapy for the treatment of metastatic prostate cancer. However, because of the mainly renal excretion of the tracer, the kidneys are one of the most limiting organs. The purpose of this study was to examine the post-therapeutic changes in renal function over time and to identify risk factors for developing renal toxicity. We also tested the reliability of markers for renal function monitoring. Fifty-five patients with castrate-resistant metastatic prostate cancer treated with at least three cycles of [{sup 177}Lu]Lu-PSMA-617 were investigated. Renal function was assessed through laboratory tests (creatinine, GFR, cystatin C) and Tc-99 m-MAG3 measurements. Adverse events were classified according to the Common Terminology Criteria for Adverse Events (CTCAE) v4.0. To identify risk factors for renal toxicity, we used Pearson's correlation coefficient and the corresponding p values. None of the 55 patients experienced severe nephrotoxicity (grade 3/4). In 14 patients (25%), we observed increased creatinine levels of CTC 1 or 2 . There were 16 cases of increased GFR (grade 1/2). At the baseline, only 14 patients had elevated cystatin C. However, post-therapeutic cystatin C was elevated in 32 patients (58%). A significant effect on renal function was found for age (p = 0.049), hypertension (p = 0.001) and pre-existing kidney disease (p = 0.001). The most reliable predictive markers of nephrotoxicity were TER-MAG3 and cystatin C. Renal toxicity in patients treated with [{sup 177}Lu]Lu-PSMA-617 was low. There was no (sub)acute grade 3 or 4 nephrotoxicity. (orig.)

New lanthanide(III) complexes of chiral nonadendate macrocyclic amine derived from (1R,2R)-1,2-diaminocyclohexane and 2,6-diformyl-4-methylphenol

Energy Technology Data Exchange (ETDEWEB)

Paluch, Marta [Department of Chemistry, University of Wroclaw, 14 F. Joliot-Curie, 50-383 Wroclaw (Poland); Lisowski, Jerzy [Department of Chemistry, University of Wroclaw, 14 F. Joliot-Curie, 50-383 Wroclaw (Poland)], E-mail: jurekl@wchuwr.chem.uni.wroc.pl

2008-02-28

The series of complexes [LnH{sub 4}L(NO{sub 3}){sub 2}](NO{sub 3}){sub 2}.nH{sub 2}O (Ln = La, Ce, Pr, Nd, Gd, Tb, Ho, Er, Tm) of the positively charged protonated form of a chiral macrocyclic amine H{sub 4}L{sup +}, derived from the 3 + 3 condensation product of (1R,2R)-1,2-diaminocyclohexane and 2,6-diformyl-4-methylphenol, have been synthesized. The series of complexes Na{sub x}[LnL](X){sub y}(OH){sub x-y}.n(solv) (X = NO{sup 3-} or Cl{sup -}, and Ln = La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu) of the deprotonated anionic form of the ligand, L{sup 3-}, have also been synthesised. The complexes have been characterised by elemental analyses, {sup 1}H NMR and ESI MS spectra. The X-ray crystal structures of the [LaH{sub 4}L(NO{sub 3}){sub 2}](NO{sub 3}){sub 2}.5CH{sub 3}OH and [GdH{sub 4}L(NO{sub 3}){sub 2}](NO{sub 3}){sub 2}.5CH{sub 3}OH complexes have been determined. The two complexes are isostructural, and the protonated macrocycle acts as pentadentate ligand. The Ln(III) ion is bound to three phenolate oxygen atoms and two amine nitrogen atoms of the macrocyclic ligand and its coordination sphere is completed by the two axial bidendate nitrate anions.

Low Estrogen Receptor (ER)-Positive Breast Cancer and Neoadjuvant Systemic Chemotherapy: Is Response Similar to Typical ER-Positive or ER-Negative Disease?

Science.gov (United States)

Landmann, Alessandra; Farrugia, Daniel J; Zhu, Li; Diego, Emilia J; Johnson, Ronald R; Soran, Atilla; Dabbs, David J; Clark, Beth Z; Puhalla, Shannon L; Jankowitz, Rachel C; Brufsky, Adam M; Ahrendt, Gretchen M; McAuliffe, Priscilla F; Bhargava, Rohit

2018-05-08

Pathologic complete response (pCR) rate after neoadjuvant chemotherapy was compared between 141 estrogen receptor (ER)-negative (43%), 41 low ER+ (13%), 47 moderate ER+ (14%), and 98 high ER+ (30%) tumors. Human epidermal growth factor receptor 2-positive cases, cases without semiquantitative ER score, and patients treated with neoadjuvant endocrine therapy alone were excluded. The pCR rate of low ER+ tumors was similar to the pCR rate of ER- tumors (37% and 26% for low ER and ER- respectively, P = .1722) but significantly different from the pCR rate of moderately ER+ (11%, P = .0049) and high ER+ tumors (4%, P < .0001). Patients with pCR had an excellent prognosis regardless of the ER status. In patients with residual disease (no pCR), the recurrence and death rate were higher in ER- and low ER+ cases compared with moderate and high ER+ cases. Low ER+ breast cancers are biologically similar to ER- tumors. Semiquantitative ER H-score is an important determinant of response to neoadjuvant chemotherapy.

Theoretical investigations on the high light yield of the LuI3:Ce scintillator

International Nuclear Information System (INIS)

Vasil'ev, A.N.; Iskandarova, I.M.; Scherbinin, A.V.; Markov, I.A.; Bagatur'yants, A.A.; Potapkin, B.V.; Srivastava, A.M.; Vartuli, J.S.; Duclos, S.J.

2009-01-01

The extremely high scintillation efficiency of lutetium iodide doped by cerium is explained as a result of at least three factors controlling the energy transfer from the host matrix to activator. We propose and theoretically validate the possibility of a new channel of energy transfer to excitons and directly to cerium, namely the Auger process when Lu 4f hole relaxes to the valence band hole with simultaneous creation of additional exciton or excitation of cerium. This process should be efficient in LuI 3 , and inefficient in LuCl 3 . To justify this channel, we perform calculations of density of states using a periodic plane-wave density functional approach. The second factor is the increase of the efficiency of valence hole capture by cerium in the row LuCl 3 -LuBr 3 -LuI 3 . The third one is the increase of the efficiency of energy transfer from self-trapped excitons to cerium ions in the same row. The latter two factors are verified by cluster ab initio calculations. We estimate either the relaxation of these excitations and barriers for the diffusion of self-trapped holes (STH) and self-trapped exciton (STE). The performed estimations theoretically justify the high LuI 3 :Ce 3+ scintillator yield.

Problem of unstable pivots in the incomplete LU-conjugate gradient method

International Nuclear Information System (INIS)

Kershaw, D.S.

1978-01-01

Incomplete LU and incomplete-Cholesky conjugate gradient methods are becoming widely used in both laser and magnetic fusion research. In my original presentation of these methods, the problem of what to do if a pivot [L/sub ii/U/sub ii/) becomes very small or zero was raised and only partially answered by the suggestion that it be arbitrarily set to some non-zero value. In what follows it will be shown precisely how small the pivot can become before it must be fixed and precisely what value it should be set to in order to minimize the error in LU. Numerical examples will be given to show that not only does this prescription improve incomplete LU-conjugate gradient methods , but exact LU decomposition carried out with this prescription for handling small pivots and followed by a few linear or conjugate gradient iterations can be much faster than the permutations of rows and columns usually employed to circumvent small pivot problems

[{sup 177}Lu]pertuzumab: experimental studies on targeting of HER-2 positive tumour cells

Energy Technology Data Exchange (ETDEWEB)

Persson, Mikael; Gedda, Lars [Uppsala University, Biomedical Radiation Sciences, Rudbeck Laboratory, Uppsala (Sweden); Uppsala University, Experimental Urology, Rudbeck Laboratory, Uppsala (Sweden); Tolmachev, Vladimir; Andersson, Karl; Carlsson, Joergen [Uppsala University, Biomedical Radiation Sciences, Rudbeck Laboratory, Uppsala (Sweden); Sandstroem, Mattias [Uppsala University, Medical Radiation Physics, Uppsala University Hospital, Uppsala (Sweden)

2005-12-01

The new antibody pertuzumab (Omnitarg) targets the dimerisation subdomain of HER-2. The purpose of this study was to analyse whether pertuzumab retains HER-2 targeting capacity after labelling with the therapeutically interesting beta emitter {sup 177}Lu and to make initial characterisations in vitro and in vivo. Pertuzumab was conjugated with isothiocyanate-benzyl-CHX-A{sup ''}-DTPA and chelated to {sup 177}Lu. Immunoreactivity, affinity, cellular retention and internalisation were analysed using SKOV-3 cells. The affinity of non-radioactive pertuzumab was measured using a surface plasmon resonance biosensor. In vivo targeting and specific binding were assessed in Balb/c (nu/nu) mice carrying SKOV-3 xenografts. The biodistribution of {sup 177}Lu was determined 1, 3 and 7 days after [{sup 177}Lu]pertuzumab administration. Gamma camera images were taken after 3 days. The immunoreactivity of [{sup 177}Lu]pertuzumab was 85.8{+-}1.3%. The affinity of non-radioactive pertuzumab was 1.8{+-}1.1 nM, and that of [{sup 177}Lu]pertuzumab, 4.1{+-}0.7 nM. The cellular retention after 5 h pre-incubation was 90{+-}2% at 20 h. The targeting was HER-2 specific both in vitro and in vivo, since excess amounts of non-labelled antibody inhibited the uptake of labelled antibody (p<0.0001 and p<0.01, respectively). The biodistribution and gamma camera images of {sup 177}Lu showed extensive tumour uptake. Normal tissues had a surprisingly low uptake. Pertuzumab was efficiently labelled with {sup 177}Lu and showed good intracellular retention and HER-2 specific binding both in vitro and in vivo. The gamma camera images and the biodistribution study gave excellent tumour targeting results. Thus, [{sup 177}Lu]pertuzumab is of interest for further studies aimed at radionuclide therapy. (orig.)

Magnetic nanosized rare earth iron garnets R_3Fe_5O_1_2: Sol–gel fabrication, characterization and reinspection

International Nuclear Information System (INIS)

Opuchovic, Olga; Kareiva, Aivaras; Mazeika, Kestutis; Baltrunas, Dalis

2017-01-01

The magnetic nanosized rare earth iron garnets (R_3Fe_5O_1_2, where R=Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu) were prepared by an aqueous sol–gel method. Herein we present, that all these garnets can be obtained by this effective synthesis method simply by changing the temperature of the final annealing. It was also demonstrated, that a different annealing temperature leads to a different particle size distribution of the final product. The SEM analysis results revealed that the smallest particles were formed in the range of 75–130 nm. The phase purity and structure of the rare earth iron garnets were estimated using XRD analysis and Mössbauer spectroscopy. Magnetic properties were determined by magnetization measurements. The relation between the particle size, composition and magnetic properties of the sol-gel derived garnets were also discussed in this study. - Highlights: • First time series of R_3Fe_5O_1_2 (R=from Sm to Lu) are prepared by sol–gel process. • Different sintering temperature leads to the different particle size distribution. • Correlation between microstructure, composition and magnetic properties is shown.

In vivo red cell destruction by anti-Lu6

International Nuclear Information System (INIS)

Issitt, P.D.; Valinsky, J.E.; Marsh, W.L.; DiNapoli, J.; Gutgsell, N.S.

1990-01-01

An example is presented of an IgG1, anti-Lu6, that reacted by indirect antiglobulin test and was capable of destroying antigen-positive red cells in vivo. Two methods for the measurement of red cell survival, 51 Cr labeling and flow cytometry, gave the same result: 20 percent of the test dose of Lu:6 red cells was destroyed in the first hour after injection and 80 percent in the first 24 hours. The clinical relevance of the antibody was correctly predicted by an in vitro monocyte monolayer assay. The finding that this example of anti-Lu6 was clinically significant should not be taken to mean that all antibodies directed against high-incidence Lutheran and Lutheran system-related antigens will behave similarly. When such antibodies are encountered, in vivo and/or in vitro studies to assess their clinical significance are necessary before rare blood is used for transfusion

2-micron lasing in Tm:Lu2O3 ceramic: initial operation

Science.gov (United States)

Vetrovec, John; Filgas, David M.; Smith, Carey A.; Copeland, Drew A.; Litt, Amardeep S.; Briscoe, Eldridge; Schirmer, Ernestina

2018-03-01

We report on initial lasing of Tm:Lu2O3 ceramic laser with tunable output in the vicinity of 2 μm. Tm:Lu2O3 ceramic gain materials offer a much lower saturation fluence than the traditionally used Tm:YLF and Tm:YAG materials. The gain element is pumped by 796 nm diodes via a "2-for-1" crossrelaxation energy transfer mechanism, which enables high efficiency. The high thermal conductivity of the Lu2O3 host ( 18% higher than YAG) in combination with low quantum defect of 20% supports operation at high-average power. Konoshima's ceramic fabrication process overcomes the scalability limits of single crystal sesquioxides. Tm:Lu2O3 offers wide-bandwidth amplification of ultrashort pulses in a chirped-pulse amplification (CPA) system. A laser oscillator was continuously tuned over a 230 nm range from 1890 to 2120 nm while delivering up to 43W QCW output with up to 37% efficiency. This device is intended for initial testing and later seeding of a multi-pass edge-pumped disk amplifier now being developed by Aqwest which uses composite Tm:Lu2O3 disk gain elements.

Preparation of LuAG Powders with Single Phase and Good Dispersion for Transparent Ceramics Using Co-Precipitation Method

Science.gov (United States)

Pan, Liangjie; Jiang, Benxue; Fan, Jintai; Yang, Qiuhong; Zhou, Chunlin; Zhang, Pande; Mao, Xiaojian; Zhang, Long

2015-01-01

The synthesis of pure and well dispersed lutetium aluminum garnet (LuAG) powder is crucial and important for the preparation of LuAG transparent ceramics. In this paper, high purity and well dispersed LuAG powders have been synthesized via co-precipitation method with lutetium nitrate and aluminum nitrate as raw materials. Ammonium hydrogen carbonate (AHC) was used as the precipitant. The influence of aging time, pH value, and dripping speed on the prepared LuAG powders were investigated. It showed that long aging duration (>15 h) with high terminal pH value (>7.80) resulted in segregation of rhombus Lu precipitate and Al precipitate. By decreasing the initial pH value or accelerating the dripping speed, rhombus Lu precipitate was eliminated and pure LuAG nano powders were synthesized. High quality LuAG transparent ceramics with transmission >75% at 1064 nm were fabricated using these well dispersed nano LuAG powders. PMID:28793510

Preparation of LuAG Powders with Single Phase and Good Dispersion for Transparent Ceramics Using Co-Precipitation Method

Directory of Open Access Journals (Sweden)

Liangjie Pan

2015-08-01

Full Text Available The synthesis of pure and well dispersed lutetium aluminum garnet (LuAG powder is crucial and important for the preparation of LuAG transparent ceramics. In this paper, high purity and well dispersed LuAG powders have been synthesized via co-precipitation method with lutetium nitrate and aluminum nitrate as raw materials. Ammonium hydrogen carbonate (AHC was used as the precipitant. The influence of aging time, pH value, and dripping speed on the prepared LuAG powders were investigated. It showed that long aging duration (>15 h with high terminal pH value (>7.80 resulted in segregation of rhombus Lu precipitate and Al precipitate. By decreasing the initial pH value or accelerating the dripping speed, rhombus Lu precipitate was eliminated and pure LuAG nano powders were synthesized. High quality LuAG transparent ceramics with transmission >75% at 1064 nm were fabricated using these well dispersed nano LuAG powders.

Model elektronického obchodu pro služby

OpenAIRE

Zechmeisterová, Věra

2009-01-01

Obsahem práce je vytvoření modelu informačního zabezpečení služeb autoopravny a vytvoření odpovídajícího systémového řešení elektronického obchodování této autoopravny. The content of this Master thesis is the creation of the car repair shop services informational security model and also the creation of commensurate e-commerce system solution for this car repair shop. A

The quantitative analysis of 163Ho source by PIXE

International Nuclear Information System (INIS)

Sera, K.; Ishii, K.; Fujioka, M.; Izawa, G.; Omori, T.

1984-01-01

We have been studying the electron-capture in 163 Ho as a method for determining the mass of electron neutrino. The 163 Ho sources were produced with the 164 Dy(p,2n) reaction by means of a method of internal irradiation 2 ). We applied the PIXE method to determine the total number of 163 Ho atoms in the source. Proton beams of 3 MeV and a method of ''external standard'' were employed for nondestructive analysis of the 163 Ho source as well as an additional method of ''internal standard''. (author)

Reducing renal uptake of 9Y- and 177Lu-labeled alpha-melanocyte stimulating hormone peptide analogues

International Nuclear Information System (INIS)

Miao Yubin; Fisher, Darrell R.; Quinn, Thomas P.

2006-01-01

Objective: The purpose of this study was to improve the tumor-to-kidney uptake ratios of 9 Y- and 177 Lu-[1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-Re-Cys 3,4,1 , D-Phe 7 , Arg 11 ]α-melanocyte stimulating hormone 3-13 {DOTA-Re(Arg 11 )CCMSH} through coupling a negatively charged glutamic acid (Glu) to the peptide sequence. Methods: A new peptide of DOTA-Re(Glu 2 , Arg 11 )CCMSH was designed, synthesized and labeled with 9 Y and 177 Lu. Pharmacokinetics of 9 Y- and 177 Lu-DOTA-Re(Glu 2 , Arg 11 )CCMSH was determined in B16/F1 murine melanoma-bearing C57 mice. Results: 9 Y- and 177 Lu-DOTA-Re(Glu 2 , Arg 11 )CCMSH exhibited significantly (P 9 Y- and 177 Lu-DOTA-Re(Arg 11 )CCMSH at 30 min and at 2, 4 and 24 h after dose administration. The renal uptake values of 9 Y- and 177 Lu-DOTA-Re(Glu 2 , Arg 11 )CCMSH were 28.16% and 28.81% of those of 9 Y- and 177 Lu-DOTA-Re(Arg 11 )CCMSH, respectively, at 4 h postinjection. 9 Y- and 177 Lu-DOTA-Re(Glu 2 , Arg 11 )CCMSH displayed higher tumor-to-kidney uptake ratios than 9 Y- and 177 Lu-DOTA-Re(Arg 11 )CCMSH at 30 min and at 2, 4 and 24 h after dose administration. The tumor-to-kidney uptake ratio of 9 Y- and 177 Lu-DOTA-Re(Glu 2 , Arg 11 )CCMSH was 2.28 and 1.69 times of 9 Y- and 177 Lu-DOTA-Re(Arg 11 )CCMSH, respectively, at 4 h postinjection. The 9 Y- and 177 Lu-DOTA-Re(Glu 2 , Arg 11 )CCMSH activity accumulation was low in normal organs except for kidney. Conclusions: Coupling a negatively charged amino acid (Glu) to the CCMSH peptide sequence dramatically reduced the renal uptake values and increased the tumor-to-kidney uptake ratios of 9 Y- and 177 Lu-DOTA-Re(Glu 2 , Arg 11 )CCMSH, facilitating their potential applications as radiopharmaceuticals for targeted radionuclide therapy of melanoma

Scintillation properties of transparent Lu{sub 3}Al{sub 5}O{sub 12} (LuAG) ceramics doped with different concentrations of Pr{sup 3+}

Energy Technology Data Exchange (ETDEWEB)

Yanagida, Takayuki; Fukabori, Akihiro; Fujimoto, Yutaka; Kamada, Kei; Yokota, Yuui; Yoshikawa, Akira; Chani, Valery [IMRAM, Tohoku University, 2-1-1 Katahira Aoba-ku, 980-8577 Sendai (Japan); Ikesue, Akio [World Labo, Co. Ltd., Mutsuno 2-4-1, Atsuta, 456-0023 Nagoya (Japan); Kataoka, Jun [School of Advanced Science and Engineering,Waseda University, Ohkubo 3-4-1, Shinjuku, 169-0072 Tokyo (Japan)

2011-01-15

Transparent ceramics of Pr-doped (0.2 mol%, 0.6 mol%, 1 mol%, and 2 mol%) Lu{sub 3}Al{sub 5}O{sub 12} (LuAG) scintillators produced by the sintering method are discussed. These materials were cut to the specimens with physical dimensions of 5 x 5 x 2 mm{sup 3}. Similar size specimens were also prepared from Czochralski grown Pr:LuAG single crystals to compare scintillation properties. Their transmittance and radio luminescence spectra were evaluated. All specimens were highly transparent in wavelength range above 300 nm, and intense Pr{sup 3+} 5d-4f emission was detected around 310 and 370 nm under excitation with X-ray. Under {sup 137}Cs {gamma}-ray is irradiation, 2 keV photo-absorption peaks were also clearly observed in each sample. The Pr 0.6 mol% doped LuAG ceramics demonstrated highest light yield achievable among the ceramics, and it was half of that observed in the single crystals. Under pulse X-ray excitation, the decay time constants became faster when Pr concentration increased, and. the fastest decay ({proportional_to}5.7 ns time constant) was noticed in the 2 mol% doped ceramic. (copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

Emergence and present status of Lu-177 in targeted radiotherapy. The Indian scenario

Energy Technology Data Exchange (ETDEWEB)

Banerjee, S.; Das, T.; Chakraborty, S.; Venkatesh, M. [Bhabha Atomic Reseach Centre, Trombay, Mumbai (India). Radiopharmaceuticals Div.

2012-07-01

{sup 177}Lu is presently considered to be a potential radionuclide for the development of agents for radionuclide therapy owing to its favorable nuclear decay characteristics [T{sub 1/2} = 6.65 d, E{sub {beta}}{sub (max)} = 0.497 MeV, E{sub {gamma}} = 113 KeV (6.4%) and 208 KeV (11%)]. While the long half-life of this promising radioisotope offers distinct logistic advantage, particularly, in countries having limited reactor facilities, the feasibility of its large-scale production with adequate specific activity and excellent radionuclidic purity in medium flux research reactors constitute yet another desirable feature. Extensive studies have been carried out to optimize the production of this isotope, with high specific activity and radionuclidic purity by the (n,{gamma}) route using the highest available flux and the optimum irradiation time. The gradual evolution of clin ical grade {sup 177}LuCl{sub 3} as a new radiochemical, ready for commercial deployment by Radiopharmaceuticals Division, Bhabha Atomic Research Centre, to nuclear medicine centers all over India was accomplished in 2010 in a stepwise manner with the commencement of the production of high specific activity {sup 177}Lu from enriched target in 2001. Research on {sup 177}Lu has demonstrated its immense potential in radiotherapeutic applications, a direct outcome of which has resulted in indigenous development of two agents viz. {sup 177}Lu-EDTMP and {sup 177}Lu-DOTA-TATE presently being evaluated in human patients for palliative care of bone pain due to skeletal metastases and treatment of malignancies of neuroendocrine origin, respectively. Using locally produced {sup 177}Lu, the radiolabeling of a plethora of other molecules with potential applicability in radiation synovectomy and targeted therapy of malignant tumors have been successfully demonstrated. A few of these agent such as a novel {sup 177}Lu-labeled porphyrin has shown considerable promise in initial studies and is presently evaluated

Overview of Development and Formulation of ¹⁷⁷Lu-DOTA-TATE for PRRT.

Science.gov (United States)

Breeman, Wouter A P; Chan, Ho Sze; de Zanger, Rory M S; Konijnenberg, Mark K; de Blois, Erik

2016-01-01

Peptide receptor radionuclide therapy (PRRT) using radiolabeled somatostatin analogs has become an established procedure for the treatment of patients suffering from inoperable neuroendocrine cancers over-expressing somatostatin receptors. Success of PRRT depends on the availability of the radiolabeled peptide with adequately high specific activity, so that required therapeutic efficacy can be achieved without saturating the limited number of receptors available on the target lesions. Specific activity of the radionuclide and the radiolabeled somatostatin analog are therefore an important parameters. Although these analogs have been investigated and improved, and successfully applied for PRRT for more than 15 years, there are still many possibilities for further improvements that fully exploit PRRT with 177Lu-DOTA-TATE. The here summarized data presented herein on increased knowledge of the components of 177Lu-DOTA-TATE (especially the purity of 177Lu and specific activity of 177Lu) and the reaction kinetics during labeling 177Lu-DOTA-TATE clearly show that the peptide dose and dose in GBq can be varied. Here we present an overview of the development, formulation and optimisation of 177Lu-DOTA-TATE, mainly addressing radiochemical parameters.

Crystal Fields in Dilute Rare-Earth Metals Obtained from Magnetization Measurements on Dilute Rare-Earth Alloys

DEFF Research Database (Denmark)

Touborg, P.; Høg, J.

1974-01-01

Crystal field parameters of Tb, Dy, and Er in Sc, Y, and Lu are summarized. These parameters are obtained from magnetization measurements on dilute single crystals, and successfully checked by a number of different methods. The crystal field parameters vary unpredictably with the rare-earth solute....... B40, B60, and B66 are similar in Y and Lu. Crystal field parameters for the pure metals Tb, Dy, and Er are estimated from the crystal fields in Y and Lu....

Analysis of the spectrum of four-times-ionized lutetium (Lu V)

International Nuclear Information System (INIS)

Kaufman, V.; Sugar, J.

1978-01-01

Spectra of Lu obtained with a sliding spark discharge at peak currents of 50--500 A were recorded with a 10.7 m normal incidence spectrograph in the range of 500--2100 A. Intercomparison of spectra revealed a distinct separation of Lu III, IV, and V, the first two of which have already been anlayzed. The present work contains an interpretation of Lu V in which 419 lines are classified as transitions among 136 energy levels of the 4f 13 , 4f 12 5d, 4f 12 6s, and 4f 12 6p configurations. Calculated energy levels and eigenvectors, obtained with fitted values for the radial integrals, are given

Heterogeneous Uptake of HO2 Radicals onto Atmospheric Aerosols

Science.gov (United States)

George, I. J.; Matthews, P. S.; Brooks, B.; Goddard, A.; Whalley, L. K.; Baeza-Romero, M. T.; Heard, D. E.

2011-12-01

The hydroxyl (OH) and hydroperoxyl (HO2) radicals, together known as HOx, play a vital role in atmospheric chemistry by controlling the oxidative capacity of the troposphere. The atmospheric lifetime and concentrations of many trace reactive species, such as volatile organic compounds (VOCs), are determined by HOx radical levels. Therefore, the ability to accurately predict atmospheric HOx concentrations from a detailed knowledge of their sources and sinks is a very useful diagnostic tool to assess our current understanding of atmospheric chemistry. Several recent field studies have observed significantly lower concentrations of HO2 radicals than predicted using box models, where HO2 loss onto aerosols was suggested as a possible missing sink [1, 2]. However, the mechanism on HO2 uptake onto aerosols and its impact on ambient HOx levels are currently not well understood. To improve our understanding of this process, we have conducted laboratory experiments to measure HO2 uptake coefficients onto submicron aerosol particles. The FAGE (Fluorescence Assay by Gas Expansion) technique, a highly sensitive laser induced fluorescence based detection method, was used to monitor HO2 uptake kinetics onto aerosol particles in an aerosol flow tube. The application of the FAGE technique allowed for kinetic experiments to be performed under low HO2 concentrations, i.e. [HO2] atomizing dilute salt solutions or by homogeneous nucleation. HO2 uptake coefficients (γ) have been measured for single-component solid and aqueous inorganic salt and organic aerosol particles with a wide range of hygroscopicities. HO2 uptake coefficients on solid particles were below the detection limit (γ < 0.001), whereas on aqueous aerosols uptake coefficients were somewhat larger (γ = 0.001 - 0.008). HO2 uptake coefficients were highest on aerosols containing metal ions, such as Cu and Fe. Humidity and aerosol pH did not significantly impact the reactive HO2 uptake. Preliminary experiments have also

Single-crystal study of the charge density wave metal LuNiC2

Science.gov (United States)

Steiner, S.; Michor, H.; Sologub, O.; Hinterleitner, B.; Höfenstock, F.; Waas, M.; Bauer, E.; Stöger, B.; Babizhetskyy, V.; Levytskyy, V.; Kotur, B.

2018-05-01

We report on single-crystal growth, single-crystal x-ray diffraction, physical properties, and density functional theory (DFT) electronic structure as well as Fermi surface calculations for two ternary carbides, LuCoC2 and LuNiC2. Electrical resistivity measurements reveal for LuNiC2 a charge density wave (CDW) transition at TCDW≃450 K and, for T >TCDW , a significant anisotropy of the electrical resistivity, which is lowest along the orthorhombic a axis. The analysis of x-ray superstructure reflections suggest a commensurate CDW state with a Peierls-type distortion of the Ni atom periodicity along the orthorhombic a axis. DFT calculations based on the CDW modulated monoclinic structure model of LuNiC2 as compared to results of the orthorhombic parent type reveal the formation of a partial CDW gap at the Fermi level which reduces the electronic density of states from N (EF)=1.03 states/eV f.u. without CDW to N (EF)=0.46 states/eV f.u. in the CDW state. The corresponding bare DFT Sommerfeld value of the latter, γDFTCDW=0.90 mJ/mol K2, reaches reasonable agreement with the experimental value γ =0.83 (5 ) mJ/mol K2 of LuNiC2. LuCoC2 displays a simple metallic behavior with neither CDW ordering nor superconductivity above 0.4 K. Its experimental Sommerfeld coefficient, γ =5.9 (1) mJ/mol K2, is in realistic correspondence with the calculated, bare Sommerfeld coefficient, γDFT=3.82 mJ/mol K2, of orthorhombic LuCoC2.

Hvis en kartoffel er forkert, hvad er en Mars-bar så?

DEFF Research Database (Denmark)

Lichtenstein, Mia Beck; Thomsen, Freja; Hinze, Cecilie

2016-01-01

Danske unge er de slankeste af 41 europæiske unge, men de føler sig ofte tykke og går på slankekur. Hvad er årsagen, og hvorfor er det et problem?......Danske unge er de slankeste af 41 europæiske unge, men de føler sig ofte tykke og går på slankekur. Hvad er årsagen, og hvorfor er det et problem?...

[{sup 177}Lu]DOTA-anti-CD20: Labeling and pre-clinical studies

Energy Technology Data Exchange (ETDEWEB)

Audicio, Paola F., E-mail: paudicio@cin.edu.u [Departamento de Radiofarmacia, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la Republica, Mataojo 2055, 11400 Montevideo (Uruguay); Castellano, Gustavo, E-mail: gcas@famaf.unc.edu.a [FaMAF, Universidad Nacional de Cordoba, Ciudad Universitaria, 5016 Cordoba (Argentina); Tassano, Marcos R.; Rezzano, Maria E.; Fernandez, Marcelo [Departamento de Radiofarmacia, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la Republica, Mataojo 2055, 11400 Montevideo (Uruguay); Riva, Eloisa [Clinica Hematologica ' Prof. Dra. L. Diaz' , Hospital de Clinicas. Av. Italia. sn, Montevideo (Uruguay); Robles, Ana; Cabral, Pablo; Balter, Henia; Oliver, Patricia [Departamento de Radiofarmacia, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la Republica, Mataojo 2055, 11400 Montevideo (Uruguay)

2011-07-15

Anti-CD20 (Rituximab), a specific chimeric monoclonal antibody used in CD20-positive Non-Hodgkin's Lymphoma, was conjugated to a bifunctional quelate (DOTA) and radiolabeled with {sup 177}Lu through a simple method. [{sup 177}Lu]-DOTA-anti-CD20 was obtained with a radiochemical purity higher than 97%, and showed good chemical and biological stability, maintaining its biospecificity to CD20 antigens. Monte Carlo simulation showed high doses deposited on a spheroid tumor mass model. This method seems to be an appropriate alternative for the production of [{sup 177}Lu]-DOTA-anti-CD20 as therapeutic radiopharmaceutical.

Lu AA21004, a novel multimodal antidepressantwith activity exerted through serotonergic targets

DEFF Research Database (Denmark)

Mork, A.; Pehrson, A.; Montezinho, L. C. P.

2012-01-01

Background: Lu AA21004 is a multimodal antidepressant that functions as a 5-HT3 and 5-HT7 receptor antagonist, 5-HT1B receptor partial agonist, 5-HT1A receptor agonist and inhibitor of the 5-HT transporter in vitro. Here we investigated preclinical effects of Lu AA21004 1) on target occupancies, 2...... (5-HT), noradrenaline (NA), dopamine (DA), acetylcholine (ACh), histamine (Hist)] were measured by microdialysis. Antidepressant potential was assessed in the forced swim test using Flinders Sensitive Line (FSL) rats. Moreover, effects of Lu AA21004 on acquisition, consolidation and recall...

Development of 177Lu-phytate Complex for Radiosynovectomy

Directory of Open Access Journals (Sweden)

Hassan Yousefnia

2013-05-01

Full Text Available Objective(s: In this work a new possible agent for radiosynovectomy has been targeted for articular pain palliation. Materials and Methods: Lu-177 of 2.6-3 GBq/mg specific activity was obtained by irradiation of natural Lu2O3 sample with thermal neutron flux of 4 × 1013 n.cm-2.s-1. The product was converted into chloride form which was further used for labeling of 177Lu-phytate complex and checked using ITLC (MeOH: H2O: acetic acid, 4: 4: 2, as mobile phase. The complex stability and viscosity were checked in the final solution up to seven days. The prepared complex solution (100 µCi/100 µl was injected intra-articularly to male rat knee joint. Leakage of radioactivity from injection site and its distribution in organs were investigated up to seven days. Results: The complex was successfully prepared with high radiochemical purity (>99.9 %. Approximately, the whole injected dose has remained in injection site seven days after injection. Conclusion: The complex was proved to be a feasible agent for cavital radiotherapy in oncology and rheumatology

Cation sorption at the smectite edges: From transition metals to Y and Lu

International Nuclear Information System (INIS)

Schlegel, M.L.

2007-01-01

Complete text of publication follows: Introduction: Clay minerals can adsorb trace elements in soils and weathering formations, a sorption property which is also a key-point for the use of clay materials in nuclear waste repositories. Retention can occur either by adsorption on the clay basal plane or at the layer edges, depending on physicochemical conditions. Building on previous identification of sorption sites of transition metals [1-3], this study shows how the geometry of Y and Lu surface complexes on layer edges of clay minerals can be identified. Materials and methods: Suspensions of purified clay minerals (hectorite or Al-montmorillonite, 2 and 1 g/L, respectively) were reacted in 0.5 M NaCl at pH 6 (Al-montmorillonite) and 7 (hectorite) with sorbates at concentrations of 50 μM (Y) and 100 μM (Lu). Self-supporting films of reacted clay minerals were obtained by slowly filtering suspension aliquots on cellulose nitrate filters. Yttrium K-edge and Lu L3-edge polarized EXAFS (PEXAFS) spectra of the self-supporting films were collected in fluorescence mode on the FAME beamline (ESRF, France). PEXAFS data were reduced, and analyzed using standard procedures. Results and interpretation: Small but significant angular dependences were observed for all P-EXAFS data, meaning that the Y and Lu binding environments are anisotropic. Coordination spheres of 7 O at 2.36 Angstroms and 8 O at 2.27 Angstroms, were observed for Y and Lu, respectively, comparable with d(Ln-O) distances measured by EXAFS spectroscopy [4]. Lutetium sorbed on Al-montmorillonite was surrounded by an Al-shell at 3.35 Angstroms, consistent with Lu sharing edges with Al octahedra and partially incorporated in a gibbsite-like interlayer. Both Y and Lu sorbed on hectorite were surrounded by cationic shells. Modelling of these cationic contributions yielded one out-of-plane Si/Mg shell at 3.16 Angstroms (Y) or 3.04 Angstroms (Lu), and two in-plane (Mg/Si) shells at 3.50, and 3.97 Angstroms for Y, or

Cation sorption at the smectite edges: From transition metals to Y and Lu

Energy Technology Data Exchange (ETDEWEB)

Schlegel, M.L. [CEA/DANS/DPC/SCP Lab React Surfaces and Interfaces, F-91191 Gif Sur Yvette (France)

2007-07-01

Complete text of publication follows: Introduction: Clay minerals can adsorb trace elements in soils and weathering formations, a sorption property which is also a key-point for the use of clay materials in nuclear waste repositories. Retention can occur either by adsorption on the clay basal plane or at the layer edges, depending on physicochemical conditions. Building on previous identification of sorption sites of transition metals [1-3], this study shows how the geometry of Y and Lu surface complexes on layer edges of clay minerals can be identified. Materials and methods: Suspensions of purified clay minerals (hectorite or Al-montmorillonite, 2 and 1 g/L, respectively) were reacted in 0.5 M NaCl at pH 6 (Al-montmorillonite) and 7 (hectorite) with sorbates at concentrations of 50 {mu}M (Y) and 100 {mu}M (Lu). Self-supporting films of reacted clay minerals were obtained by slowly filtering suspension aliquots on cellulose nitrate filters. Yttrium K-edge and Lu L3-edge polarized EXAFS (PEXAFS) spectra of the self-supporting films were collected in fluorescence mode on the FAME beamline (ESRF, France). PEXAFS data were reduced, and analyzed using standard procedures. Results and interpretation: Small but significant angular dependences were observed for all P-EXAFS data, meaning that the Y and Lu binding environments are anisotropic. Coordination spheres of 7 O at 2.36 Angstroms and 8 O at 2.27 Angstroms, were observed for Y and Lu, respectively, comparable with d(Ln-O) distances measured by EXAFS spectroscopy [4]. Lutetium sorbed on Al-montmorillonite was surrounded by an Al-shell at 3.35 Angstroms, consistent with Lu sharing edges with Al octahedra and partially incorporated in a gibbsite-like interlayer. Both Y and Lu sorbed on hectorite were surrounded by cationic shells. Modelling of these cationic contributions yielded one out-of-plane Si/Mg shell at 3.16 Angstroms (Y) or 3.04 Angstroms (Lu), and two in-plane (Mg/Si) shells at 3.50, and 3.97 Angstroms for Y

EGR-1 regulates Ho-1 expression induced by cigarette smoke

International Nuclear Information System (INIS)

Chen, Huaqun; Wang, Lijuan; Gong, Tao; Yu, Yang; Zhu, Chunhua; Li, Fen; Wang, Li; Li, Chaojun

2010-01-01

As an anti-oxidant molecule, heme oxygenase-1 (HO-1) has been implicated in the protection of lung injury by cigarette smoke (CS). The mechanisms regulating its expression have not been defined. In this report, the role of early growth response 1 (EGR-1) in the regulation of Ho-1 expression was investigated. In C57BL/6 mice with CS exposure, HO-1 was greatly increased in bronchial epithelial cells and alveolar inflammatory cells. In primary cultured mouse lung fibroblasts and RAW264.7 cells exposed to cigarette smoke water extract (CSE), an increase in HO-1 protein level was detected. In addition, CSE induced HO-1 expression was decreased in Egr-1 deficient mouse embryo fibroblasts (Egr-1 -/- MEFs). Nuclear localization of EGR-1 was examined in mouse lung fibroblasts after exposure to CSE. Luciferase reporter activity assays showed that the enhancer region of the Ho-1 gene containing a proposed EGR-1 binding site was responsible for the induction of HO-1. A higher increase of alveolar mean linear intercept (Lm) was observed in lung tissues, and a larger increase in the number of total cells and monocytes/macrophages from bronchial alveolar lavage fluid was found in CS-exposed mice by loss of function of EGR-1 treatment. In summary, the present data demonstrate that EGR-1 plays a critical role in HO-1 production induced by CS.

166Ho-chitosan as a radiation synovectomy agent - biocompatibility study of 166Ho-chitosan in rabbits

International Nuclear Information System (INIS)

Kim, Sug Jun; Lee, Soo Yong; Jeon, Dae Geun; Lee Jong Seok

1997-01-01

Radiation synovectomy is a noninvasive therapy that has been investigated as an alternative to surgical synovectomy. It is been successfully employed in the treatment of synovitis in rheumatoid arthrits and other inflammatory arthropathies. We developed the 166 Ho-chitosan complex for possible use as a radiation synovectomy agent. Holmium is the more practical isotope based on its higher radioactivity and logner half-life. And isotope based on its higher radioactivity and logner half-life. And chitosan is ideal and suitable particles based on its soluble and biodegradable characteristics. So we investigated the biocompatibility of the 166 Ho-chitosan complex to evaluated the suitability as a radiation synovectomy agent. In this study, we performed in vivo and in vitro stability test and biodistribution test. Our results indicate that 166 Ho-chitosan may be an effective radiopharmaceutical for radiation synovectomy. (author). 30 refs., 7 tabs

In Vivo Measurement and Characterization of a Novel Formulation of [177Lu]-DOTA-Octreotate

Directory of Open Access Journals (Sweden)

Dale Bailey

2016-01-01

Full Text Available Objective(s:Lutetium-177 can be made with high specific activity and with no other isotopes of lutetium present, referred to as “No Carrier Added” (NCA 177Lu. We have radiolabelled DOTA-conjugated peptide DOTA‐(Tyr3‐octreotate with NCA 177Lu (“NCA-LuTATE” and used it in nearly 40 therapeutic administrations for subjects with neuroendocrine tumours or meningiomas. In this paper, we report on our initial studies on aspects of the biodistribution and dosimetry of NCA-LuTATE from gamma camera 2D whole body (WB and quantitative 3D SPECT (qSPECT 177Lu imaging. Methods: Thirteen patients received 39 NCA-LuTATE injections. Extensive WB planar and qSPECT imaging was acquired at approximately 0.5, 4, 24 and 96 h to permit estimates of clearance and radiation dose estimation using MIRD-based methodology (OLINDA-EXM. Results:The average amount of NCA-Lutate administered per cycle was 7839±520 MBq. Bi-exponential modelling of whole body clearance showed half lives for the fast & slow components of t½=2.1±0.6 h and t½=58.1±6.6 h respectively. The average effective dose to kidneys was 3.1±1.0 Gy per cycle. In eight patients completing all treatment cycles the average total dose to kidneys was 11.7±3.6 Gy. Conclusions: We have shown that NCA-LuTATE has an acceptable radiation safety profile and is a suitable alternative to Carrier-Added 177Lu formulations. The fast component of the radiopharmaceutical clearance was closely correlated with baseline renal glomerular filtration rate, and this had an impact on radiation dose to the kidneys. In addition, it has less radioactive waste issues and requires less peptide per treatment.

Slaďování pracovního a osobního života pracovníků

OpenAIRE

Šauerová, Martina

2017-01-01

Diplomová práce se zabývá tématem slaďování pracovního a osobního života ve vybrané společnosti. Práce je rozdělena do tří části – na teoretickou, analytickou a závěrečnou část. Teoretická část vysvětluje atraktivitu a důležitost tohoto tématu, popisuje jednotlivé nástroje umožňující slazení profesního a osobního života a zároveň poukazuje na možné komplikace jednotlivých přístupů, a to jak z pohledu zaměstnavatele, tak i zaměstnance. Analytická část zkoumá a následně vyhodnocuje současný sta...

Double ferromagnetism in single-crystal Gd-Y-Lu alloys

International Nuclear Information System (INIS)

Ito, T.; Oka, M.; Legvold, S.; Beaudry, B.J.

1984-01-01

Magnetization, electrical resistivity, specific-heat and thermal-expansion measurements have been made on Gd-Y-Lu single crystals. Low isofield magnetization data for the a-axis sample of Gd 75 Y/sub 17.5/ Lu/sub 7.5/ exhibit two different Curie-Weiss regimes, which suggests double ferromagnetism. Electrical resistivity, specific-heat, and thermal-expansion data show two anomalies at the transition temperatures. The anomaly at 231.5 K shows a lambda-type second-order phase transition and the anomaly at 223 K shows a sharp spike first-order phase transition

Intrinsic magnetic properties of hexagonal LuFeO3 and the effects of nonstoichiometry

Directory of Open Access Journals (Sweden)

Jarrett A. Moyer

2014-01-01

Full Text Available We used oxide molecular-beam epitaxy in a composition-spread geometry to deposit hexagonal LuFeO3 (h-LuFeO3 thin films with a monotonic variation in the Lu/Fe cation ratio, creating a mosaic of samples that ranged from iron rich to lutetium rich. We characterized the effects of composition variation with x-ray diffraction, atomic force microscopy, scanning transmission electron microscopy, and superconducting quantum interference device magnetometry. After identifying growth conditions leading to stoichiometric film growth, an additional sample was grown with a rotating sample stage. From this stoichiometric sample, we determined stoichiometric h-LuFeO3 to have a TN = 147 K and Ms = 0.018 μB/Fe.

ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphology.

Science.gov (United States)

Manford, Andrew G; Stefan, Christopher J; Yuan, Helen L; Macgurn, Jason A; Emr, Scott D

2012-12-11

Endoplasmic reticulum-plasma membrane (ER-PM) junctions are conserved structures defined as regions of the ER that tightly associate with the plasma membrane. However, little is known about the mechanisms that tether these organelles together and why such connections are maintained. Using a quantitative proteomic approach, we identified three families of ER-PM tethering proteins in yeast: Ist2 (related to mammalian TMEM16 ion channels), the tricalbins (Tcb1/2/3, orthologs of the extended synaptotagmins), and Scs2 and Scs22 (vesicle-associated membrane protein-associated proteins). Loss of all six tethering proteins results in the separation of the ER from the PM and the accumulation of cytoplasmic ER. Importantly, we find that phosphoinositide signaling is misregulated at the PM, and the unfolded protein response is constitutively activated in the ER in cells lacking ER-PM tether proteins. These results reveal critical roles for ER-PM contacts in cell signaling, organelle morphology, and ER function. Copyright © 2012 Elsevier Inc. All rights reserved.

Yrast bands and signature inversion in double odd 162,164Lu

International Nuclear Information System (INIS)

Cardona, M.A.; Hojman, D.; Kreiner, A.J.; Somacal, H.; Davidson, J.; Davidson, M.; Acuna, D. de; Napoli, D.R.; Rico, J.; Burch, R.; Bazzacco, D.; Lenzi, S.M.; Rossi Alvarez, C.; Blasi, N.; Lo Bianco, G.

1996-01-01

High spin rotational bands in 162 Lu and 164 Lu have been studied by means of the 139 La( 28 Si,5n) and 139 La( 29(30) Si,4(5)n) reactions respectively. For both nuclei the yrast sequence which is associated with the πh 11/2 x νi 13/2 configuration shows the signature inversion feature. (orig.)

Mixed phosphates of the Na3PO4 - LnPO4 systems

International Nuclear Information System (INIS)

Slivko, T.A.; Smirnova, I.N.; Zimina, G.V.; Spiridonov, F.M.; Chudinova, N.N.

2002-01-01

The phase relationships in the systems Na 3 PO 4 - LnPO 4 (subsolidus 950 Deg C cross-sections), where Ln=Sm, Eu, Tb, Dy, Ho, Tm, Yb, Lu, were studied by X-ray analysis. Reactions of the components were deduced, formed phases were separated and identified. The Na 6 Ln 3 (PO 4 ) 5 (Ln=Dy, Ho, Tm), Na 3 Ln 2 (PO 4 ) 3 (Ln=Tm, Yb, Lu) compounds and phases of the unstable composition Na 6+x Ln 3-x/3 (PO 4 ) 5 (Ln=Yb, Lu, 0 ≤ x ≤ 1.5) were detected for the first time. In all systems the existence of the Na 3-x Ln x/3 PO 4 unstable composition phase on the basis of the high temperature modification of sodium phosphate (sp. gr. Fm3m) is established, suggesting that stabilization of this modification by rare earth ions is possible [ru

Ultrasmall, water dispersible, TWEEN80 modified Yb:Er:NaGd(WO4)2 nanoparticles with record upconversion ratiometric thermal sensitivity and their internalization by mesenchymal stem cells

Science.gov (United States)

Cascales, Concepción; Paíno, Carlos L.; Bazán, Eulalia; Zaldo, Carlos

2017-05-01

This work presents the synthesis by coprecipitation of diamond shaped Yb:Er:NaGd(WO4)2 crystalline nanoparticles (NPs) with diagonal dimensions in the 5-7 nm × 10-12 nm range which have been modified with TWEEN80 for their dispersion in water, and their interaction with mesenchymal stem cells (MSCs) proposed as cellular NP vehicles. These NPs belong to a large family of tetragonal Yb:Er:NaT(XO4)2 (T = Y, La, Gd, Lu; X = Mo, W) compounds with green (2H11/2 + 4S3/2 → 4I15/2) Er-related upconversion (UC) efficiency comparable to that of Yb:Er:β-NaYF4 reference compound, but with a ratiometric thermal sensitivity (S) 2.5-3.5 times larger than that of the fluoride. At the temperature range of interest for biomedical applications (˜293-317 K/20-44 °C) S = 108-118 × 10-4 K-1 for 20 at%Yb:5 at%Er:NaGd(WO4)2 NPs, being the largest values so far reported using the 2H11/2/4S3/2 Er intensity ratiometric method. Cultured MSCs, incubated with these water NP emulsions, internalize and accumulate the NPs enclosed in endosomes/lysosomes. Incubations with up to 10 μg of NPs per ml of culture medium maintain cellular metabolism at 72 h. A thermal assisted excitation path is discussed as responsible for the UC behavior of Yb:Er:NaT(XO4)2 compounds.

Electrochemistry and spectroelectrochemistry of tert-butylcalix[4]arene bridged bis double-decker lutetium(III) phthalocyanine, Lu2Pc4 and dimeric lutetium(III) phthalocyanine, Lu2Pc2(OAc)2

International Nuclear Information System (INIS)

Koca, Atif; Ceyhan, Tanju; Erbil, Mehmet K.; Ozkaya, Ali Riza; Bekaroglu, Ozer

2007-01-01

In this study, electrochemical, electrochromic and spectroelectrochemical properties of a tert-butylcalix[4]arene bridged bis double-decker lutetium(III) phthalocyanine (Lu 2 Pc 4 2) were investigated explicitly as compared with a tert-butylcalix[4]arene bridged dimeric lutetium(III) phthalocyanine [Lu 2 Pc 2 (OAc) 2 1]. Distinctive differences between electrochemical and electrochromic properties of 1 and 2 were detected. Moreover, the properties of 1 and 2 were compared with previously reported S 4 (CH 2 ) 4 bridged Lu 2 Pc 2 (OAc) 2 and Lu 2 Pc 4 . The calixarene bridged phthalocyanine (Pc) compounds, 1 and 2 showed well-defined electrochromic behaviour with green-blue and blue-purple colour transitions. The enhanced electrochromic properties of 2, as compared to 1, were attributed to its double-decker structure, probably allowing the formation of suitable ion channels for the counter ion movement in the solid film

Tumoral fibrosis effect on the radiation absorbed dose of 177Lu-Tyr3-octreotate-gold nanoparticles and 177Lu-Tyr3-octreotate radiopharmaceuticals

International Nuclear Information System (INIS)

Zambrano R, O. D.

2015-01-01

In this work was comparatively evaluated the effect of tumoral fibrosis in the radiation absorbed dose of the radiopharmaceutical 177 Lu-Tyr 3 -octreotate with and without gold nanoparticles. For this, was used an experimental array of tumoral fibrosis and computer models based on Monte Carlo calculations to simulate tumoral micro environments without fibrosis and with fibrosis. The computer simulation code Penelope (Penetration Energy Loss of Positron and Electrons) and MCNP (Monte Carlo N-particle Transport Code System) which are based on the Monte Carlo methodology were used to create the computer models for the simulation of the transport of particles (emitted by 177 Lu) in the micro environments (without fibrosis and with fibrosis) with the purpose of calculating the radiation absorbed dose in the interstitial space and in the nucleus of cancer cells. The first computational model consisted of multiple concentric spheres (as onion shells) with the radioactive source homogeneously distributed in the shell between 5 and 10 μm in diameter which represents the internalization of the radioactive source into the cell cytoplasm as it occurs in target specific radiotherapy. The concentric spheres were useful to calculate the radiation absorbed dose in depth in the models without fibrosis and with fibrosis. Furthermore, there were constructed other computer models using two different codes that simulate the transport of radiation (Penelope and MCNP). These models consist of seven spheres that represent cancer cells (HeLa cells) of 10 μm in diameter and each one of them contain another smaller sphere in the center that represents the cell nucleus. A comparison was done of the radiation absorbed dose in the nucleus of the cells, calculated with both codes, Penelope and MCNP. The radioactive source ( 177 Lu) used for the simulations was given to the codes by means of a convoluted spectrum of the most important beta particles (high percentage emission). To this spectrum

Wobbling phonon excitations, coexisting with normal deformed structures in 163Lu

International Nuclear Information System (INIS)

Jensen, D.R.; Hagemann, G.B.; Hamamoto, I.; Oedegard, S.W.; Bergstroem, M.; Herskind, B.; Sletten, G.; Toermaenen, S.; Wilson, J.N.; Tjoem, P.O.; Spohr, K.; Huebel, H.; Goergen, A.; Schoenwasser, G.; Bracco, A.; Leoni, S.; Maj, A.; Petrache, C.M.; Bednarczyk, P.; Curien, D.

2002-01-01

Wobbling is a rotational mode unique to a triaxial body. The Lu-Hf isotopes with N∼94 at high spin provide a possible region of nuclei with pronounced triaxiality. We have investigated 163 Lu through the fusion-evaporation reaction 139 La( 29 Si,5n) 163 Lu with a beam energy of 152 MeV. Three excited bands decaying into the known, presumably triaxial, superdeformed (TSD) band built on the i 13/2 proton orbital are observed. The electromagnetic properties of the connecting transitions from the two strongest populated excited TSD bands have been investigated. New particle-rotor calculations in which one i 13/2 quasiproton is coupled to the core of triaxial shape produce a variety of bands, whose properties can clearly be interpreted either as 'wobbling' or 'cranking' motion of the core. Evidence for the assignment of the excited TSD bands as one, and possibly even two wobbling phonon modes built on the yrast TSD band in 163 Lu is given. These triaxial bands coexist with bands built on quasiparticle excitations in the normal deformed (ND) minimum for which new data are also presented

Comparison of the luminescent properties of Lu3Al5O12:Pr crystals and films under synchrotron radiation excitation

International Nuclear Information System (INIS)

Zorenko, Yu.; Gorbenko, V.; Zorenko, T.; Voznyak, T.; Nizankovskiy, S.

2016-01-01

The work is dedicated to comparative investigation of the luminescent properties of Lu 3 Al 5 O 12 :Pr(LuAG:Pr) single crystals and single crystalline films using excitation by synchrotron radiation with an energy of 3.7–25 eV in the exciton range of LuAG host. We have found that the differences in the excitation spectra and luminescence decay kinetics of LuAG:Pr crystals and films are caused by involving the LuAl antisite defects and oxygen vacancies in the crystals and Pb 2+ flux related dopants in the films in the excitation processes of the Pr 3+ luminescence. Taking into account these differences, we have determined the energy structure of the Pr 3+ ions in LuAG host and estimated the differences in the energies of creation of excitons bound with the isolated Pr 3+ ions in LuAG:Pr films and the dipole Pr–LuAl antisite defect centers in the crystal counterpart. - Highlights: • Comparison of the luminescent properties of LuAG:Pr single crystals and films. • Superposition of the Pr 3+ and defect centers luminescence of LuAG:Pr crystal. • Different creation energies of an excitons bound with the Pr 3+ in LuAG:Pr crystals and films. • More faster decay kinetics of the Pr 3+ luminescence in LuAG:Pr films. • Low content of slow emission component in LuAG:Pr films.

Effective lattice stabilization of gadolinium aluminate garnet (GdAG via Lu3+ doping and development of highly efficient (Gd,LuAG:Eu3+ red phosphors

Directory of Open Access Journals (Sweden)

Jinkai Li, Ji-Guang Li, Zhongjie Zhang, Xiaoli Wu, Shaohong Liu, Xiaodong Li, Xudong Sun and Yoshio Sakka

2012-01-01

Full Text Available The metastable garnet lattice of Gd3Al5O12 is stabilized by doping with smaller Lu3+, which then allows an effective incorporation of larger Eu3+ activators. The [(Gd1−xLux1−yEuy]3Al5O12 (x = 0.1–0.5, y = 0.01–0.09 garnet solid solutions, calcined from their precursors synthesized via carbonate coprecipitation, exhibit strong luminescence at 591 nm (the 5D0 → 7F1 magnetic dipole transition of Eu3+ upon UV excitation into the charge transfer band (CTB at ~239 nm, with CIE chromaticity coordinates of x = 0.620 and y = 0.380 (orange-red. The quenching concentration of Eu3+ was estimated at ~5 at.% (y = 0.05, and the quenching was attributed to exchange interactions. Partial replacement of Gd3+ with Lu3+ up to 50 at.% (x = 0.5 while keeping Eu3+ at the optimal content of 5 at.% does not significantly alter the peak positions of the CTB and 5D0 → 7F1 emission bands but slightly weakens both bands owing to the higher electronegativity of Lu3+. The effects of processing temperature (1000–1500 °C and Lu/Eu contents on the intensity, quantum efficiency, lifetime and asymmetry factor of luminescence were thoroughly investigated. The [(Gd0.7Lu0.30.95Eu0.05]3Al5O12 phosphor processed at 1500 °C exhibits a high internal quantum efficiency of ~83.2% under 239 nm excitation, which, in combination with the high theoretical density, favors its use as a new type of photoluminescent and scintillation material.

Nd-doped Lu3Al5O12 single-crystal scintillator for X-ray imaging

International Nuclear Information System (INIS)

Sugiyama, Makoto; Fujimoto, Yutaka; Yanagida, Takayuki; Totsuka, Daisuke; Chani, Valery; Yokota, Yuui; Yoshikawa, Akira

2013-01-01

The optical and scintillation properties of Nd-doped Lu 3 Al 5 O 12 (Nd:LuAG) crystals grown by the Czochralski (Cz) method were examined under X-ray excitation. Their applicability for X-ray imaging was also inspected. The radioluminescence spectrum induced by X-rays showed a broad host emission and sharp Nd 3+ 4f–4f emission peaks in the UV to visible wavelengths. The light output current of the Nd:LuAG was 85% of that of a standard CdWO 4 X-ray scintillator. The afterglow value measured 20 ms after X-ray irradiation was 1.5%. An X-ray radiographic image was successfully obtained using the Nd:LuAG scintillator coupled with the charge coupled device (CCD) photodetector. -- Highlights: ► The Nd:LuAG single crystal was produced to perform X-ray imaging test. ► The sample exhibited the 85% light output current of the standard CdWO 4 . ► The afterglow intensity of the sample was very high compared with the CdWO 4 . ► The X-ray radiographic image was obtained from the Nd:LuAG single crystal

An electro-amalgamation approach to isolate no-carrier-added 177Lu from neutron irradiated Yb for biomedical applications

International Nuclear Information System (INIS)

Chakravarty, Rubel; Das, Tapas; Dash, Ashutosh; Venkatesh, Meera

2010-01-01

Introduction: A novel two-step separation process for the production of no-carrier-added (NCA) 177 Lu from neutron irradiated Yb target through an electrochemical pathway employing mercury-pool cathode has been developed. Methods: A two-cycle electrolysis procedure was adopted for separation of 177 Lu from 177 Lu/Yb mixture in lithium citrate medium. The influence of different experimental parameters on the separation process was investigated and optimized for the quantitative deposition of Yb in presence of 177 Lu. The first electrolysis was performed for 50 min in the 177 Lu/Yb feed solution at pH 6 applying a potential of 8 V using platinum electrode as anode and mercury as the cathode. The second electrolysis was performed under the same conditions using fresh electrodes. The radionuclidic and chemical purity of 177 Lu was determined by using gamma ray spectrometry and atomic absorption spectrometry. The suitability of 177 Lu for biomedical applications was ascertained by labeling 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid D-Phe 1 -Tyr 3 -octreotate(DOTA-TATE) with 177 Lu. Results: This process could provide NCA 177 Lu with >99.99% radionuclidic purity and an overall separation yield of ∼99% was achieved within 3-4 h. The Hg content in the product was determined to be 98% was obtained with DOTA-TATE under the optimized reaction conditions. Conclusions: An efficient strategy for the separation of NCA 177 Lu, suitable for biomedical applications, has been developed.

Návrh na slaďování pracovního a soukromého života ve vybraném podniku

OpenAIRE

Švejdíková, Romana

2013-01-01

Diplomová práce se zabývá problematikou slaďování práce a soukromého života ve zvolené organizaci. Detailně popisuje nástroje slaďování práce a soukromého života, srovnává teoretické poznatky se skutečností. Práce identifikuje možnosti a překážky slaďování práce a soukromého života u zaměstnanců zkoumané firmy. Na základě semistrukturovaného rozhovoru a dotazníkového šetření jsou navržena opatření pro optimální slaďování práce a života v organizaci. The diploma thesis deals with the issue ...

OH, HO2, and HO2* Radical Chemistry During PROPHET-AMOS 2016: Measurements and Model Comparison

Science.gov (United States)

Bottorff, B.; Lew, M.; Rickly, P.; Stevens, P. S.

2017-12-01

The hydroxyl (OH) and peroxy radicals, both the hydroperoxy radical (HO2) and organic peroxy radicals (RO2), play an important role in atmospheric chemistry. In addition to controlling lifetimes of many trace gases important to issues of global climate change, reactions of these radicals can also lead to the production of ozone and secondary organic aerosols in the atmosphere. Previous measurements of these radicals in remote forest environments have shown serious discrepancies with modeled concentrations. These results bring into question our understanding of the atmospheric chemistry of isoprene and other biogenic VOCs under low NOX conditions. In the summer of 2016, OH, HO2 and HO2* (HO2 + αRO2) radicals were measured using the Indiana University Laser-Induced Fluorescence Fluorescence Assay by Gas Expansion (LIF-FAGE) technique as part of the Program for Research on Oxidants: PHtochemistry, Emissions, and Transport- Atmospheric Measurements of Oxidants in Summer (PROPHET-AMOS). This campaign took place in a forested area in northern Michigan characterized by high mixing ratios of isoprene and low mixing ratios of NOX. Ambient measurements from this campaign will be compared to previous measurements at this site and to modeled predictions using both the Regional Atmospheric Chemistry Mechanism (RACM2) and the Master Chemical Mechanism. Potential interferences associated with the OH measurements will also be examined.

Occupational Competence for Improving Industrial Enterprise Competitive Standards / Profesní Kompetence Pro Zlepšení Konkurenčních Standardů Průmyslového Podniku

Directory of Open Access Journals (Sweden)

Krčmarská Lucie

2013-09-01

Full Text Available Úspěchy firem jsou většinou poměřovány jejich dosaženými výsledky. Za základ těchto úspěchů lze považovat úroveň kompetencí lidí, kteří pro firmu pracují. Kompetence lidí chápeme jako souhrn dosahovaného výkonu a přinášeného potenciálu. Jestliže chybí jedno, pak chybí i kompetence jako celek. Problémy, které vznikají ve firmách můžete tedy převést na chybějící nebo nedostačující kompetence a je tedy nutné doplnit to, co v oblasti kompetencí chybí. Uvědomí-li si firma význam kompetencí lidí ve vztahu k úspěchům nebo neúspěchům a zaměří-li se na jejich rozvoj, odstraňuje tím příčiny vznikajících problémů, ne jen jejich viditelné problémy. Článek je zaměřen na posouzení kompetencí a kompetenčních modelů jako významného nástroje v oblasti řízení lidských zdrojů.

The coordination number of Lu(III) in a mixed system of methanol and water

International Nuclear Information System (INIS)

Arisaka, M.; Takuwa, N.; Suganuma, H.

2000-01-01

The stability constants (β 1(F) ) of the monofluoro complex of Lu(III) and those (β 1(Cl) ) of the monochloride solvent-shared ion-pair of Lu(III) have been determined in mixed solvents of methanol and water at 0.10 and 1.00 mol x dm -3 ionic strengths, respectively. The variation in lnβ 1(F) with an increase in the mole fraction of methanol (X s ) in the mixed solvent system showed an acute-angled convex inflection point at X s ∼ 0.12, an acute-angled concave inflection point at X s ∼ 0.22, and another acute-angled convex inflection point at X s ∼ 0.27. It was concluded that the first and the second convex inflection points denoted the CN of Lu 3+ from CN = 8 to a mixture of CN = 8 and 7 and from CN = 8 and 7 to a mixture containing CN = 6, respectively. The concave point is the starting point of a change in the CN of Lu(III) in LuF 2+ from CN = 8 to a mixture of CN = 8 and 7. The values at two inflection points of the CN around Lu 3+ are consistent with the inflection points of the variation in the values of lnβ 1(Cl ) versus the dielectric constant of the mixed solvent. (author)

Synthesis, characterization, and in vitro evaluation of a radio-metal organic framework composed of in vivo generator {sup 166}Dy/{sup 166}Ho and DOTMP as a novel agent for bone marrow ablation

Energy Technology Data Exchange (ETDEWEB)

Vosoghi, Sara; Shirvani-Arani, Simindokht; Bahrami-Samani, Ali; Salek, Nafise; Mirerezaei, Ehsan; Jalilian, Amir Reza [Nuclear Science and Technology Research Institute (NSTRI), Tehran (Iran, Islamic Republic of)

2016-07-01

In this study, the MOF concept contributed to the preparation of a novel, bone-ablating agent composed of Cu(II) using the in vivo generator {sup 166}Dy/{sup 166}Ho and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetramethylene phosphonic acid (DOTMP). The product was characterized (IR, elemental analysis: CHN, ICM-MS, PIXE, DLS, XRD) and quality-controlled (radio-thin layer chromatography (RTLC)). The stability and in vitro hydroxyapatite binding was checked up to one week at 37 C in human serum. Radio-MOF crystals and colloidal radio-MOF particles were obtained by varying the synthesizing conditions (including pH and temperature), and they had similar IR patterns and similar elemental analysis results. The estimated chemical formula was [1Lu-1Cu-1Cl-1DOTMP] for both. The final product was synthesized at pH = 8 while stirring at room temperature using {sup 166}Dy/{sup 166}Ho-nitrate, CuCl{sub 2}, and DOTMP (yield > 99%, RTLC). Dynamic light scattering (DLS) measurements showed particles in the size range of 60 to 100 nm for the resultant radio-MOF particles (RMP). In vitro binding experiments showed acceptable bone-seeking affinity of the prepared formula even after one week of storage in human serum at 37 C. Importantly, this is the first study of the use of the MOF concept to provide a highly-stable organometallic compound containing {sup 166}Dy/{sup 166}Ho in vivo generator for bone marrow ablation.

Lu-Hf isotope systematics of fossil biogenic apatite and their effects on geochronology

Science.gov (United States)

Herwartz, Daniel; Münker, Carsten; Tütken, Thomas; Hoffmann, J. Elis; Wittke, Andreas; Barbier, Bruno

2013-01-01

Reliable methods for direct dating of biogenic apatite from pre-Pleistocene fossils are currently not available, and recent attempts using the Lu-Hf decay system yielded highly inaccurate ages for both bones and teeth. The geological processes accounting for this poor accuracy of Lu-Hf chronometry are not yet understood. Here we explore Lu-Hf systematics in fossil bones and teeth in detail, by applying five different sample digestion techniques that are tested on bones and composites of bone and sediment. Our current dataset implies that dissolution methods only slightly affect the resulting Lu-Hf ages, while clear differences between the individual digestion techniques became apparent for element concentrations. By analysing the insoluble leftovers from incomplete sample dissolution, four main reservoirs of Hf in fossil bones were identified: (1) a radiogenic end-member associated with apatite; (2) an unradiogenic end-member represented by the authigenic minerals or the embedding sediment; (3) a highly unradiogenic end-member that can be attributed to detrital zircon; and (4) a moderately soluble phase (probably a Zr(Hf)-phosphate) that yielded very low Lu/Hf but a highly radiogenic Hf isotope composition at the same time. This Zr(Hf)-phase must have been precipitated within the fossil bone sample at a late stage of burial history, thereby incorporating radiogenic 176Hf released from apatite surfaces over geological timescales. A second focus of our study is the effect of different sediment matrices and of crystal size on the preservation of pristine Lu-Hf isotope compositions in bioapatite. Because near-depositional Lu-Hf ages of phosphate fossils have previously been reported for the London Clay (England) and a calcareous marl from Tendaguru (Tanzania), we herein investigate specimens fossilised in carbonate matrices (calcareous marl from Oker, Germany; carbonate concretions from the Santana Formation, Brazil; carbonate from the Eifel, Germany) and argillaceous

Effect of Gd substitution on structure and spectroscopic properties of (Lu,Gd)2O3:Eu ceramic scintillator

Science.gov (United States)

Cao, Maoqing; Hu, Zewang; Ivanov, Maxim; Dai, Jiawei; Li, Chaoyu; Kou, Huamin; Shi, Yun; Chen, Haohong; Xu, Jiayue; Pan, Yubai; Li, Jiang

2018-02-01

In this paper, (Lu1-xGdx)2O3:Eu (x = 0, 0.1, 0.3, 0.5, 0.7, 0.9) ceramics were consolidated by the solid-state reaction method combined with vacuum sintering without sintering aids. We investigated the effect of the varying contents of Gd2O3 on the structure and spectroscopic properties of (Lu1-xGdx)2O3:Eu ceramics. X-ray diffraction (XRD) patterns indicate that proper amount of Gd2O3 can incorporate well with Lu2O3 and form Lu2O3-Gd2O3 solid solution. However, excessive Gd3+-doping in Lu2O3 will lead to the cubic phase transforming into monoclinic even hexagonal phase. The Gd3+ substitution no more than 50% of Lu2O3 enhances the radioluminescence, and reduces the fluorescence lifetime. Transmittance, photoluminescence, and radiation damage of the (Lu1-xGdx)2O3:Eu scintillation ceramics were also studied.

Development of a therapeutic radiopharmaceutical 177Lu-DOTA- Minigastrin for potential use in PRRT

International Nuclear Information System (INIS)

Lopez Bularte, A.C.; Nevares, N.N.; Zapata, A.M.; Perez, J.H.; Crudo, J.L.; Puerta Yepes, N.; Rojo, A.M.

2010-01-01

The aim of this work is to obtain 177 Lu-DOTA-Minigastrin with high radiochemical purity (RP) and the highest specific activity (Ae) as possible, using a locally produced (Nuclear Reactor RA-3, Ezeiza Atomic Center) 177 LuCl 3 of an intermediate level of Ae (between 6.36 to 17.95 Ci/mg of 176 Lu) ) and also to perform in vitro and in vivo stability tests, dose calculation in normal mice and its extrapolation to a human model. (authors) [es

Observation of states beyond band termination in 156,157,158Er and strongly deformed structures in 173,174,175Hf

International Nuclear Information System (INIS)

Riley, M A; Djongolov, M K; Evans, A O

2006-01-01

High-spin terminating bands in heavy nuclei were first identified in nuclei around 158 Er 90 . While examples of terminating states have been identified in a number of erbium isotopes, almost nothing is known about the states lying beyond band termination. In the present work, the high-spin structure of 156,157,158 Er has been studied using the Gammasphere spectrometer. The subject of triaxial superdeformation and 'wobbling' modes in Lu nuclei has rightly attracted a great deal of attention. Very recently four strongly or superdeformed (SD) sequences have been observed in 174 Hf, and cranking calculations using the Ultimate Cranker code predict that such structures may have significant triaxial deformation. We have performed two experiments in an attempt to verify the possible triaxial nature of these bands. A lifetime measurement was performed to confirm the large (and similar) deformation of the bands. In addition, a high-statistics, thin-target experiment took place to search for linking transitions between the SD bands, possible wobbling modes, and new SD band structures

An electro-amalgamation approach to isolate no-carrier-added 177Lu from neutron irradiated Yb for biomedical applications.

Science.gov (United States)

Chakravarty, Rubel; Das, Tapas; Dash, Ashutosh; Venkatesh, Meera

2010-10-01

A novel two-step separation process for the production of no-carrier-added (NCA) (177)Lu from neutron irradiated Yb target through an electrochemical pathway employing mercury-pool cathode has been developed. A two-cycle electrolysis procedure was adopted for separation of (177)Lu from (177)Lu/Yb mixture in lithium citrate medium. The influence of different experimental parameters on the separation process was investigated and optimized for the quantitative deposition of Yb in presence of (177)Lu. The first electrolysis was performed for 50 min in the (177)Lu/Yb feed solution at pH 6 applying a potential of 8 V using platinum electrode as anode and mercury as the cathode. The second electrolysis was performed under the same conditions using fresh electrodes. The radionuclidic and chemical purity of (177)Lu was determined by using gamma ray spectrometry and atomic absorption spectrometry. The suitability of (177)Lu for biomedical applications was ascertained by labeling 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid D-Phe(1)-Tyr(3)-octreotate(DOTA-TATE) with (177)Lu. This process could provide NCA (177)Lu with >99.99% radionuclidic purity and an overall separation yield of ∼99% was achieved within 3-4 h. The Hg content in the product was determined to be 98% was obtained with DOTA-TATE under the optimized reaction conditions. An efficient strategy for the separation of NCA (177)Lu, suitable for biomedical applications, has been developed. Copyright © 2010 Elsevier Inc. All rights reserved.

Návrh internetového obchodu pro firmu

OpenAIRE

Fikáčková, Barbora

2007-01-01

Bakalářské práce analyzuje problémy související s tvorbou internetového obchodu. Obsahuje návrh vhodného řešení pro zlepšení budoucího postavení firmy AMAR marketing s.r.o. a jeho ekonomické zhodnocení. Bachelor work analyzes problems in connection with creation of internet shop. for the firm AMAR marketing s.r.o. It contains analysis of suitable solution, leading to improve future position of the firm AMAR marketing s.r.o. and its econo-mic evulation. A

Development of the therapeutic radiopharmaceutical 117Lu-DOTA-Minigastrin for potential use in PRRT

International Nuclear Information System (INIS)

Lopez Bularte, Ana C.; Nevares, Noemi; Zapata, Miguel; Perez, Juan; Crudo, Jose L.

2009-01-01

Objective: The main objectives of this work were to obtain 177 Lu-DOTA-Minigastrin with high radiochemical purity (RP) and specific activity (SA) as high as possible, using locally produced medium SA 177 LuCl3 (range 6,36-9,73 Ci/mg of 176 Lu), and to carry out in vitro and in vivo stability tests. Materials and methods: For a typical labelling, 20 or 15 μg of DOTA-MG (pi Chem, Austria) dissolved in ammonium acetate buffer pH 6 were mixed with 1mCi of 177 LuCl3 (SA = 6,36, 7,52 y 9,73 Ci/mg). The solution was incubated for 30 min. at 80 C degrees (pH 5,5). The stability assays in saline (SS) were carried out by incubation of the radiopharmaceutical with SA of 0.05 mCi/ μg of peptide in 80 μ of SS for 24 and 48 h at room temperature. The stability assays in human serum (HS) were carried out by incubation of 2.5 μ of 177 Lu-DOTA-MG with SA of 0.05 mCi/ μg of peptide in 500 μl of HS for 15 min. and 2 h at 37 C degrees. The samples were centrifuged at 3000 xg for 5 min. The supernatant (SN) was taken and acetonitrile (ACN) was added in a ratio 2:3 (SP:ACN). The solution was centrifuged at 3000 xg for 5 min. and the resulting supernatant was concentrated by ultra-filtration (Vivaspin 500, Sartorius). The concentrated SN was analyzed by Reverse Phase High Performance Liquid Chromatography (RP-HPLC) in order to determine the radiochemical purity. The serum protein binding was calculated taking into account the relation between the pellets activity in respect to the total activity. Bio distributions of 177 Lu-DOTA-MG in normal mice were done at 15 and 30 min., 1 and 4 h p.i. The results were expressed as percentage of injected activity per gram of tissue (%IAgr). Results: 20 μg of peptide were labelled with different SA 177 LuCl3 (6,36, 7,52 and 9,73 Ci/mg of 176 Lu) resulting in high radiochemical purities 96,31 %, 98,95 % and 97.57 %, respectively (SA 0.05 mCi/μg of peptide). 15 ug of peptide were labelled with 177 LuCl3 (SA 7,52 Ci/mg of 176 Lu) obtaining a

HoCaMA: Home Care Hybrid Multiagent Architecture

Science.gov (United States)

Fraile, Juan A.; Bajo, Javier; Abraham, Ajith; Corchado, Juan M.

Home Care is one of the main objectives of Ambient Intelligence. Nowadays, the disabled and elderly population, which represents a significant part of our society, requires novel solutions for providing home care in an effective way. In this chapter, we present HoCaMA, a hybrid multiagent architecture that facilitates remote monitoring and care services for disabled patients at their homes. HoCaMA combines multiagent systems and Web services to facilitate the communication and integration with multiple health care systems. In addition, HoCaMA focuses on the design of reactive agents capable of interacting with different sensors present in the environment, and incorporates a system of alerts through SMS and MMS mobile technologies. Finally, it uses Radio Frequency IDentification and JavaCard technologies to provide advanced location and identification systems, as well as automatic access control facilities. HoCaMA has been implemented in a real environment and the results obtained are presented within this chapter.

Development of 177Lu-DOTA-anti-CD20 for radioimmunotherapy

International Nuclear Information System (INIS)

Hassan Yousefnia; Amir Reza Jalilian; Ali Bahrami-Samani; Simindokht Shirvani-Arani; Mohammad Ghannadi-Maragheh; Azim Arbabi; Edalat Radfar

2011-01-01

Rituximab was successively labeled with 177 Lu-lutetium chloride. 177 Lu chloride was obtained by thermal neutron flux (4 x 1013 n cm -2 s -1 ) of natural Lu 2 O 3 sample with a specific activity of 2.6-3 GBq/mg. The macrocyclic bifunctional chelating agent, N-succinimidyl-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA-NHS) was prepared at 25 deg C using DOTA, N-hydroxy succinimide (NHS) in CH 2 Cl 2 . DOTA-rituximab was obtained by the addition of 1 mL of a rituximab pharmaceutical solution (5 mg/mL, in phosphate buffer, pH 7.8) to a glass tube pre-coated with DOTA-NHS (0.01-0.1 mg) at 25 deg C with continuous mild stirring for 15 h. Radiolabeling was performed at 37 deg C in 24 h. Radio-thin layer chromatography showed an overall radiochemical purity of >98% at optimized conditions (specific activity = 444 MBq/mg, labeling efficacy; 82%). The final isotonic 177 Lu-DOTA-rituximab complex was checked by gel electrophoresis for structure integrity control. Radio-TLC was performed to ensure that only one species was present after filtration through a 0.22 μm filter. Preliminary biodistribution studies in normal rats were carried out to determine complex distribution of the radioimmunoconjugate up to 168 h. The biodistribution data were in accordance with other antiCD20 radioimmunoconjugates already reported. (author)

Ln3+ (Ln=Ce, Tb, Dy) and Hf doping of LuI3 powders – A material and spectroscopic study

International Nuclear Information System (INIS)

Wiatrowska, Aneta; Keur, Wilco; Ronda, Cees

2016-01-01

The moisture sensitivity of LuI 3 :Ce,Hf and luminescent properties of undoped LuI 3 and LuI 3 :M (M=Ce 3+ , Tb 3+ , Dy 3+ ) powders were investigated. The possibility of improving the air and moisture stability of LuI 3 :Ce by Hf doping was tested. It was proven that the Hf contribution to the LuI 3 :Ce stability is very limited and is insignificant to render LuI 3 :Ce scintillator powders suitable for applications. Photoluminescence results of LuI 3 without dopants added on purpose showed luminescence due to a plurality of rare-earth elements' impurities. Two types of self-trapped luminescence were found. Energy transfer between host lattice, self-trapped excitons and rare-earth ions was investigated.

Electronic transitions of Ho in Pb2Sr2HoCu3O8 observed by inelastic neutron scattering

International Nuclear Information System (INIS)

Soderholm, L.; Loong, C.; Xue, J.S.; Hammonds, J.P.; Greedan, J.E.; Maric, M.

1993-01-01

The electronic behavior of the 5 I 8 Russell Saunders ground multiplet of Ho 3+ in Pb 2 Sr 2 HoCu 3 O 8 has been investigated using inelastic neutron scattering. We observe ten peaks in the excitation spectra that are associated with crystal field transitions. The peaks are only slightly broader than expected from instrument resolution, indicating that there are no strong interactions between the local Ho f states and the CuO conduction states. Comparing the energies and intensities of the experimental peaks with those expected from modeling convinces us that there are at least three states populated at the temperature of our experiment (15 K), making the assignments of transitions very difficult in the absence of further data

Revisiting the level scheme of the proton emitter 151Lu

International Nuclear Information System (INIS)

Wang, F.; Sun, B.H.; Liu, Z.; Scholey, C.; Eeckhaudt, S.; Grahn, T.; Greenlees, P.T.; Jones, P.; Julin, R.; Juutinen, S.; Kettelhut, S.; Leino, M.; Nyman, M.; Rahkila, P.; Saren, J.; Sorri, J.; Uusitalo, J.; Ashley, S.F.; Cullen, I.J.; Garnsworthy, A.B.; Gelletly, W.; Jones, G.A.; Pietri, S.; Podolyak, Z.; Steer, S.; Thompson, N.J.; Walker, P.M.; Williams, S.; Bianco, L.; Darby, I.G.; Joss, D.T.; Page, R.D.; Pakarinen, J.; Rigby, S.; Cullen, D.M.; Khan, S.; Kishada, A.; Gomez-Hornillos, M.B.; Simpson, J.; Jenkins, D.G.; Niikura, M.; Seweryniak, D.; Shizuma, Toshiyuki

2015-01-01

An experiment aiming to search for new isomers in the region of proton emitter 151 Lu was performed at the Accelerator Laboratory of the University of Jyväskylä (JYFL), by combining the high resolution γ-ray array JUROGAM, gas-filled RITU separator and GREAT detectors with the triggerless total data readout acquisition (TDR) system. In this proceeding, we revisit the level scheme of 151 Lu by using the proton-tagging technique. A level scheme consistent with the latest experimental results is obtained, and 3 additional levels are identified at high excitation energies. (author)

A prenatally detected adrenal cyst treated by adrenal-sparing ...

African Journals Online (AJOL)

Ahmet Dursun and Munevver Ho ¸sgo¨ r. A neonatal case of left adrenal cyst detected in utero and ... Correspondence to Munevver Ho ¸sgör, MD, PhD, Department II of Pediatric. Surgery, Dr Behcet Uz Children's Hospital, Koruturk Mh. ..... Radiology 1986; 161:631–633. 13 Erbil Y, Salmasliog˘lu A, Barbaros U, Bozbora A, ...

Metastatic Bone Pain Palliation using 177Lu-Ethylenediaminetetramethylene Phosphonic Acid

International Nuclear Information System (INIS)

Alavi, Mehrosadat; Omidvari, Shapour; Mehdizadeh, Alireza; Jalilian, Amir R.; Bahrami-Samani, Ali

2015-01-01

177 Lu-ethylenediaminetetramethylene phosphonic acid (EDTMP) is presently suggested as an excellent bone seeking radionuclide for developing metastatic bone pain (MBP) palliation agent owing to its suitable nuclear decay characteristics. To find the exact dosage and its efficiency, this clinical study was performed on the human being, using 177 Lu-EDTMP for MBP palliation. 177 Lu-EDTMP was prepared by Iran, atomic energy organization. Thirty consecutive patients with determined tumors, incontrollable MBP, and positive bone scan at 4 weeks before the beginning of the study participated in this study in the nuclear medicine ward. 177 Lu-EDTMP in the form of sterile slow IV injection was administered with a dose of 29.6 MBq/kg. Short form of brief pain inventory questionnaire was used to evaluate the efficiency of the intervention. Questionnaires were filled out by an expert nuclear physician every 2 weeks while the cell blood count was also checked every 2 weeks up to 12 weeks for evaluation of bone marrow suppression and hematological toxicity. Furthermore, whole body scan was done at days 1, 3, and 7. Twenty-five patients showed a significant pain relief since 2 weeks after the injection, and continued until the end of the follow up period (12 weeks). There were no significant early complications such as bone marrow suppression, hematological toxicity, and no systemic adverse effects. No complication was observed in renal function. Twenty one patients showed flare phenomenon that was started after the 12.2 ± 1.78 h lasting for 38.4 ± 23.08. Sixteen patients (53%) were completely treated; nine patients (30%) showed a partial response, and five patients (17%) had no response to treatment. Total response to treatment was achieved in 25 patients (83%). At the end of the evaluation, no bone marrow suppression or hematologic toxicity was observed. 177 Lu-EDTMP has shown suitable physical and biological properties with good results in long term bone pain relief for

Metastatic Bone Pain Palliation using (177)Lu-Ethylenediaminetetramethylene Phosphonic Acid.

Science.gov (United States)

Alavi, Mehrosadat; Omidvari, Shapour; Mehdizadeh, Alireza; Jalilian, Amir R; Bahrami-Samani, Ali

2015-01-01

(177)Lu-ethylenediaminetetramethylene phosphonic acid (EDTMP) is presently suggested as an excellent bone seeking radionuclide for developing metastatic bone pain (MBP) palliation agent owing to its suitable nuclear decay characteristics. To find the exact dosage and its efficiency, this clinical study was performed on the human being, using (177)Lu-EDTMP for MBP palliation. (177)Lu-EDTMP was prepared by Iran, atomic energy organization. Thirty consecutive patients with determined tumors, incontrollable MBP, and positive bone scan at 4 weeks before the beginning of the study participated in this study in the nuclear medicine ward. (177)Lu-EDTMP in the form of sterile slow IV injection was administered with a dose of 29.6 MBq/kg. Short form of brief pain inventory questionnaire was used to evaluate the efficiency of the intervention. Questionnaires were filled out by an expert nuclear physician every 2 weeks while the cell blood count was also checked every 2 weeks up to 12 weeks for evaluation of bone marrow suppression and hematological toxicity. Furthermore, whole body scan was done at days 1, 3, and 7. Twenty-five patients showed a significant pain relief since 2 weeks after the injection, and continued until the end of the follow up period (12 weeks). There were no significant early complications such as bone marrow suppression, hematological toxicity, and no systemic adverse effects. No complication was observed in renal function. Twenty one patients showed flare phenomenon that was started after the 12.2 ± 1.78 h lasting for 38.4 ± 23.08. Sixteen patients (53%) were completely treated; nine patients (30%) showed a partial response, and five patients (17%) had no response to treatment. Total response to treatment was achieved in 25 patients (83%). At the end of the evaluation, no bone marrow suppression or hematologic toxicity was observed. (177)Lu-EDTMP has shown suitable physical and biological properties with good results in long term bone pain relief for

Metastatic Bone Pain Palliation using 177Lu-Ethylenediaminetetramethylene Phosphonic Acid

Science.gov (United States)

Alavi, Mehrosadat; Omidvari, Shapour; Mehdizadeh, Alireza; Jalilian, Amir R.; Bahrami-Samani, Ali

2015-01-01

177Lu-ethylenediaminetetramethylene phosphonic acid (EDTMP) is presently suggested as an excellent bone seeking radionuclide for developing metastatic bone pain (MBP) palliation agent owing to its suitable nuclear decay characteristics. To find the exact dosage and its efficiency, this clinical study was performed on the human being, using 177Lu-EDTMP for MBP palliation. 177Lu-EDTMP was prepared by Iran, atomic energy organization. Thirty consecutive patients with determined tumors, incontrollable MBP, and positive bone scan at 4 weeks before the beginning of the study participated in this study in the nuclear medicine ward. 177Lu-EDTMP in the form of sterile slow IV injection was administered with a dose of 29.6 MBq/kg. Short form of brief pain inventory questionnaire was used to evaluate the efficiency of the intervention. Questionnaires were filled out by an expert nuclear physician every 2 weeks while the cell blood count was also checked every 2 weeks up to 12 weeks for evaluation of bone marrow suppression and hematological toxicity. Furthermore, whole body scan was done at days 1, 3, and 7. Twenty-five patients showed a significant pain relief since 2 weeks after the injection, and continued until the end of the follow up period (12 weeks). There were no significant early complications such as bone marrow suppression, hematological toxicity, and no systemic adverse effects. No complication was observed in renal function. Twenty one patients showed flare phenomenon that was started after the 12.2 ± 1.78 h lasting for 38.4 ± 23.08. Sixteen patients (53%) were completely treated; nine patients (30%) showed a partial response, and five patients (17%) had no response to treatment. Total response to treatment was achieved in 25 patients (83%). At the end of the evaluation, no bone marrow suppression or hematologic toxicity was observed. 177Lu-EDTMP has shown suitable physical and biological properties with good results in long term bone pain relief for patients

Antitenascin antibody 81C6 armed with {sup 177}Lu: in vivo comparison of macrocyclic and acyclic ligands

Energy Technology Data Exchange (ETDEWEB)

Yordanov, Alexander T. [Department of Radiology, Duke University Medical Center Durham, NC 27710 (United States); Hens, Marc [Department of Radiology, Duke University Medical Center Durham, NC 27710 (United States); Pegram, Charles [Department of Pathology, Duke University Medical Center Durham, NC 27710 (United States); Bigner, Darell D. [Department of Pathology, Duke University Medical Center Durham, NC 27710 (United States); Zalutsky, Michael R. [Department of Radiology, Duke University Medical Center Durham, NC 27710 (United States)]. E-mail: zalut001@mc.duke.edu

2007-02-15

Introduction: When labeled with iodine-131, the antitenascin monoclonal antibody (mAb) 81C6 has shown promise as a targeted radiotherapeutic in patients with brain tumors. Because of its more favorable {gamma}-ray properties, lutetium-177 might be a better low-energy {beta}-emitter for this type of therapy. Materials and Methods: Chimeric 81C6 (ch81C6) was labeled with {sup 177}Lu using the acyclic 1B4M ligand and the macrocyclic ligands NHS-DOTA and MeO-DOTA and evaluated for binding to tenascin. Three paired-label tissue distribution experiments were performed in normal mice receiving one of the {sup 177}Lu-labeled immunoconjugates plus {sup 125}I-labeled ch81C6 labeled using Iodogen. Paired-label experiments in athymic mice bearing subcutaneous D54 MG human glioma xenografts were done to directly compare the biodistribution of ch81C6-1B4M-{sup 177}Lu and {sup 125}I-labeled ch81C6, and ch81C6-MeO-DOTA-{sup 177}Lu and {sup 125}I-labeled ch81C6. Similar comparisons were done using murine (mu) instead of ch81C6. The primary parameter utilized for evaluation was the {sup 177}Lu/{sup 125}I uptake ratio in each tissue. Results: In the studies performed in normal mice, the NHS-DOTA ligand yielded the highest {sup 177}Lu/{sup 125}I uptake ratios in tissues indicative of loss of label from the chelate; for this reason, only 1B4M and MeO-DOTA were evaluated further. The {sup 177}Lu/{sup 125}I ratio in bone increased gradually with time for the chimeric conjugates; however, there were no significant differences between ch81C6-1B4M-DTPA-{sup 177}Lu and ch81C6-MeO-DOTA-{sup 177}Lu. In contrast, mu81C6-1B4M-DTPA-{sup 177}Lu and mu81C6-MeO-DOTA-{sup 177}Lu showed a more dramatic increase in the {sup 177}Lu/{sup 125}I ratio in bone - from 2.4{+-}0.3 and 1.7{+-}0.2 at Day 1 to 8.5{+-}1.1 and 4.2{+-}0.5 at Day 7, respectively. Conclusion: With these antitenascin constructs, the nature of the mAb had a profound influence on the relative degree of loss of {sup 177}Lu from these

Third-line treatment and 177Lu-PSMA radioligand therapy of metastatic castration-resistant prostate cancer: a systematic review

International Nuclear Information System (INIS)

Edler von Eyben, Finn; Roviello, Giandomenico; Kiljunen, Timo; Kairemo, Kalevi; Joensuu, Timo; Uprimny, Christian; Virgolini, Irene

2018-01-01

There is a controversy as to the relative efficacy of 177 Lu prostate specific membrane antigen (PSMA) radioligand therapy (RLT) and third-line treatment for patients with metastatic castration-resistant prostate cancer (mCRPC). The aim of our systematic review was to elucidate whether 177 Lu-PSMA RLT and third-line treatment have similar effects and adverse effects (PROSPERO ID CRD42017067743). The review followed Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Searches in Pubmed and Embase selected articles up to September 2017. A search in ClinicalTrials.gov indicated ongoing studies. The meta-analysis used the random-effects model. Twelve studies including 669 patients reported 177 Lu-PSMA RLT. Overall, 43% of the patients had a maximum decline of PSA of ≥50% following treatment with 177 Lu-PSMA RLT. The treatment with 177 Lu-PSMA-617 and 177 Lu-PSMA for imaging and therapy (I and T) had mainly transient adverse effects. Sixteen studies including 1338 patients reported third-line treatment. Overall, 21% of the patients had a best decline of PSA of ≥50% following third-line treatment. After third-line treatment with enzalutamide and cabazitaxel, adverse effects caused discontinuation of treatment for 10% to 23% of the patients. 177 Lu-PSMA RLT gave a best PSA decline ≥50% more often than third-line treatment (mean 44% versus 22%, p = 0.0002, t test). 177 Lu-PSMA RLT gave objective remission more often than third-line treatment (overall 31 of 109 patients versus 43 of 275 patients, p = 0.004, χ 2 test). Median survival was longer after 177 Lu-PSMA RLT than after third-line treatment, but the difference was not statistically significant (mean 14 months versus 12 months, p = 0.32, t test). Adverse effects caused discontinuation of treatment more often for third-line treatment than for 177 Lu-PSMA RLT (22 of 66 patients versus 0 of 469 patients, p < 0.001, χ 2 test). As for patients with mCRPC, treatment with 177 Lu

Measurement of thermal neutron cross-section and resonance integral for the 165Ho(n,γ) 166gHo reaction using electron linac-based neutron source

Science.gov (United States)

Nguyen, Van Do; Pham, Duc Khue; Kim, Tien Thanh; Kim, Guinyun; Lee, Manwoo; Kim, Kyung Sook; Kang, Heung-Sik; Cho, Moo-Hyun; Ko, In Soo; Namkung, Won

2011-01-01

The thermal neutron cross-section and the resonance integral of the 165Ho(n,γ) 166gHo reaction have been measured by the activation method using a 197Au(n,γ) 198Au monitor reaction as a single comparator. The high-purity natural Ho and Au foils with and without a cadmium shield case of 0.5 mm thickness were irradiated in a neutron field of the Pohang neutron facility. The induced activities in the activated foils were measured with a calibrated p-type high-purity Ge detector. The correction factors for the γ-ray attenuation ( Fg), the thermal neutron self-shielding ( Gth), the resonance neutron self-shielding ( Gepi) effects, and the epithermal neutron spectrum shape factor ( α) were taken into account. The thermal neutron cross-section for the 165Ho(n,γ) 166gHo reaction has been determined to be 59.7 ± 2.5 barn, relative to the reference value of 98.65 ± 0.09 barn for the 197Au(n,γ) 198Au reaction. By assuming the cadmium cut-off energy of 0.55 eV, the resonance integral for the 165Ho(n,γ) 166gHo reaction is 671 ± 47 barn, which is determined relative to the reference value of 1550 ± 28 barn for the 197Au(n,γ) 198Au reaction. The present results are, in general, good agreement with most of the previously reported data within uncertainty limits.

Characterization of the ER-Targeted Low Affinity Ca2+ Probe D4ER

Directory of Open Access Journals (Sweden)

Elisa Greotti

2016-09-01

Full Text Available Calcium ion (Ca2+ is a ubiquitous intracellular messenger and changes in its concentration impact on nearly every aspect of cell life. Endoplasmic reticulum (ER represents the major intracellular Ca2+ store and the free Ca2+ concentration ([Ca2+] within its lumen ([Ca2+]ER can reach levels higher than 1 mM. Several genetically-encoded ER-targeted Ca2+ sensors have been developed over the last years. However, most of them are non-ratiometric and, thus, their signal is difficult to calibrate in live cells and is affected by shifts in the focal plane and artifactual movements of the sample. On the other hand, existing ratiometric Ca2+ probes are plagued by different drawbacks, such as a double dissociation constant (Kd for Ca2+, low dynamic range, and an affinity for the cation that is too high for the levels of [Ca2+] in the ER lumen. Here, we report the characterization of a recently generated ER-targeted, Förster resonance energy transfer (FRET-based, Cameleon probe, named D4ER, characterized by suitable Ca2+ affinity and dynamic range for monitoring [Ca2+] variations within the ER. As an example, resting [Ca2+]ER have been evaluated in a known paradigm of altered ER Ca2+ homeostasis, i.e., in cells expressing a mutated form of the familial Alzheimer’s Disease-linked protein Presenilin 2 (PS2. The lower Ca2+ affinity of the D4ER probe, compared to that of the previously generated D1ER, allowed the detection of a conspicuous, more clear-cut, reduction in ER Ca2+ content in cells expressing mutated PS2, compared to controls.

Gas-Phase Reactions of Doubly Charged Lanthanide Cations with Alkanes and Alkenes. Trends in Metal(2+) Reactivity

Energy Technology Data Exchange (ETDEWEB)

Gibson, John K.; Marcalo, Joaquim; Santos, Marta; Pires de Matos, Antonio; Haire, Richard G.

2008-12-08

The gas-phase reactivity of doubly-charged lanthanide cations, Ln2+ (Ln = La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu), with alkanes (methane, ethane, propane, n-butane) and alkenes (ethene, propene, 1-butene) was studied by Fourier transform ion cyclotron resonance mass spectrometry. The reaction products consisted of different combinations of doubly-charged organometallic ions?adducts or species formed via metal-ion-induced hydrogen, dihydrogen, alkyl, or alkane eliminations from the hydrocarbons?and singly-charged ions that resulted from electron, hydride, or methide transfers from the hydrocarbons to the metal ions. The only lanthanide cations capable of activating the hydrocarbons to form doubly-charged organometallic ions were La2+, Ce2+, Gd2+, and Tb2+, which have ground-state or low-lying d1 electronic configurations. Lu2+, with an accessible d1 electronic configuration but a rather high electron affinity, reacted only through transfer channels. The remaining Ln2+ reacted via transfer channels or adduct formation. The different accessibilities of d1 electronic configurations and the range of electron affinities of the Ln2+ cations allowed for a detailed analysis of the trends for metal(2+) reactivity and the conditions for occurrence of bond activation, adduct formation, and electron, hydride, and methide transfers.

The Ho–Ni–Ge system: Isothermal section and new rare-earth nickel germanides

Energy Technology Data Exchange (ETDEWEB)

Morozkin, A.V., E-mail: morozkin@tech.chem.msu.ru [Department of Chemistry, Moscow State University, Leninskie Gory, House 1, Building 3, GSP-2, Moscow 119992 (Russian Federation); Knotko, A.V. [Department of Chemistry, Moscow State University, Leninskie Gory, House 1, Building 3, GSP-2, Moscow 119992 (Russian Federation); Yapaskurt, V.O. [Department of Petrology, Faculty of Geology, Moscow State University, Leninskie Gory, Moscow 119992 (Russian Federation); Yuan, Fang; Mozharivskyj, Y. [Department of Chemistry and Chemical Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4M1 (Canada); Pani, M.; Provino, A.; Manfrinetti, P. [Institute SPIN-CNR and Dipartimento di Chimica e Chimica Industriale, Università di Genova, Via Dodecaneso 31, 16146 Genova (Italy)

2015-05-15

The Ho–Ni–Ge system has been investigated at 1070 K and up to ~60 at% Ho by X-ray diffraction and microprobe analyses. Besides the eight known compounds, HoNi{sub 5}Ge{sub 3} (YNi{sub 5}Si{sub 3}-type), HoNi{sub 2}Ge{sub 2} (CeAl{sub 2}Ga{sub 2}-type), Ho{sub 2}NiGe{sub 6} (Ce{sub 2}CuGe{sub 6}-type), HoNiGe{sub 3} (SmNiGe{sub 3}-type), HoNi{sub 0.2÷0.6}Ge{sub 2} (CeNiSi{sub 2}-type), Ho{sub 37÷34}Ni{sub 6÷24}Ge{sub 57÷42} (AlB{sub 2}-type), HoNiGe (TiNiSi-type), Ho{sub 3}NiGe{sub 2} (La{sub 3}NiGe{sub 2}-type), the ternary system contains four new compounds: Ho{sub 3}Ni{sub 11}Ge{sub 4} (Sc{sub 3}Ni{sub 11}Ge{sub 4}-type), HoNi{sub 3}Ge{sub 2} (ErNi{sub 3}Ge{sub 2}-type), Ho{sub 3}Ni{sub 2}Ge{sub 3} (Hf{sub 3}Ni{sub 2}Si{sub 3}-type) and ~Ho{sub 5}Ni{sub 2}Ge{sub 3} (unknown structure). Quasi-binary solid solutions were observed at 1070 K for Ho{sub 2}Ni{sub 17}, HoNi{sub 5}, HoNi{sub 7}, HoNi{sub 3}, HoNi{sub 2}, HoNi and Ho{sub 2}Ge{sub 3}, but no detectable solubility was found for the other binary compounds in the Ho–Ni–Ge system. Based on the magnetization measurements, the HoNi{sub 5}Ge{sub 3}, HoNi{sub 3}Ge{sub 2} and Ho{sub 3}Ni{sub 11}Ge{sub 4} (and isostructural (Tb, Dy){sub 3}Ni{sub 11}Ge{sub 4}) compounds have been found to show paramagnetic behavior down to 5 K, whereas Ho{sub 3}Ni{sub 2}Ge{sub 3} exhibits an antiferromagnetic transition at ~7 K. Additionally, the crystal structure of the new isostructural phases (Y, Yb)Ni{sub 3}Ge{sub 2} (ErNi{sub 3}Ge{sub 2}-type), Er{sub 3}Ni{sub 11}Ge{sub 4} (Sc{sub 3}Ni{sub 11}Ge{sub 4}-type) and (Y, Tb, Dy, Er, Tm){sub 3}Ni{sub 2}Ge{sub 3} (Hf{sub 3}Ni{sub 2}Si{sub 3}-type) has been also investigated. - Graphical abstract: The Ho–Ni–Ge system has been investigated at 1070 K and up to ~60 at.% Ho by X-ray and microprobe analyses. Besides the eight known compounds, i.e. HoNi{sub 5}Ge{sub 3} (YNi{sub 5}Si{sub 3}-type), HoNi{sub 2}Ge{sub 2} (CeAl{sub 2}Ga{sub 2}-type), Ho{sub 2}NiGe{sub 6} (Ce{sub 2

Comparing particles for radiosynovectomy labeled with Ho-166

International Nuclear Information System (INIS)

Argueelles, M.G.; Luppi Berlanga, I.S.; Torres, E.A.; Pereyra Molina, V.

2002-01-01

Aim: Three types of microparticles containing Ho-166 were investigated as potential agents for radiation synovectomy. These are: hydroxyapatite (HA), ferric hydroxide macro-aggregates (FHMA) and polymeric micro-spheres (PM). Labeling was performed by three different methods: coprecipitation, two steps labeling using citrate and irradiation of Ho-165 complexed to acetylacetone (AcAc) incorporated into poly-L-lactic acid spheres (PLA) by the solvent evaporation technique. Material and methods: a coprecipitation technique of holmium hydroxide and ferric hydroxide was used in order to obtain 166 Ho-FHMA. Particle size was determined by optical microscopy and selective filtration (1.2 - 100 μm). Obtainment efficiency of FHMA was always higher than 90%. Radiochemical purity was checked by thin layer chromatography using ITLC/SG and EDTA solution as solvent. In vitro stability studies were performed by incubating labelled particles in either saline, or EDTA solution. Hydroxyapatite particles were prepared from the reaction of calcium nitrate and ammonia phosphate at high pH. By strong heating of the precipitate at 800 0 C, the product becomes largely anhydrous and hardened. The yield of the hydroxyapatite synthesis was always greater than 80%. Particle size range was studied using light microscopy. Labeling was done in two steps: 166Ho-citrate was prepared by adding sufficient citric acid to the 166 Ho-Cl 3 solution. The radioactive solution was added to the particulate suspension stirring continuously. Radiolabelled particles were rinsed and separated by centrifugation. Stable Ho-165, complexed to acetylacetone (AcAc), was incorporated into PLA spheres by the solvent evaporation technique. The particle size distribution of the micro-spheres was determined by electronic microscopy. A X-ray fluorescence technique was used to determine the percentage of 165 Ho-AcAc incorporated in the microspheres by studying standards and prepared PLA spheres. Stability studies were

177Lu-DOTA-HH1, a novel anti-CD37 radio-immunoconjugate: a study of toxicity in nude mice.

Directory of Open Access Journals (Sweden)

Ada H V Repetto-Llamazares

Full Text Available CD37 is an internalizing B-cell antigen expressed on Non-Hodgkin lymphoma (NHL and chronic lymphocytic leukemia cells (CLL. The anti-CD37 monoclonal antibody HH1 was conjugated to the bifunctional chelator p-SCN-Bn-DOTA and labelled with the beta-particle emitting radionuclide 177Lu creating the radio-immunoconjugate (RIC 177Lu-DOTA-HH1 (177Lu-HH1, trade name Betalutin. The present toxicity study was performed prior to initiation of clinical studies with 177Lu-HH1.Nude mice with or without tumor xenografts were treated with 50 to 1000 MBq/kg 177Lu- HH1 and followed for clinical signs of toxicity up to ten months. Acute, life threatening bone marrow toxicity was observed in animals receiving 800 and 1000 MBq/kg 177Lu-HH1. Significant changes in serum concentrations of liver enzymes were evident for treatment with 1000 MBq/kg 177Lu-HH1. Lymphoid depletion, liver necrosis and atrophy, and interstitial cell hyperplasia of the ovaries were also observed for mice in this dose group.177Lu-DOTA-HH1 was well tolerated at dosages about 10 times above those considered relevant for radioimmunotherapy in patients with B-cell derived malignancies.The toxicity profile was as expected for RICs. Our experimental results have paved the way for clinical evaluation of 177Lu-HH1 in NHL patients.

Heavy rare earth elements affect early life stages in Paracentrotus lividus and Arbacia lixula sea urchins

Energy Technology Data Exchange (ETDEWEB)

Oral, Rahime [Ege University, Faculty of Fisheries, TR-35100 Bornova, İzmir (Turkey); Pagano, Giovanni, E-mail: gbpagano@tin.it [“Federico II” University of Naples, Department of Chemical Sciences, I-80126 Naples (Italy); Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples (Italy); Siciliano, Antonietta; Gravina, Maria [“Federico II” University of Naples, Department of Biology, I-80126 Naples (Italy); Palumbo, Anna; Castellano, Immacolata; Migliaccio, Oriana [Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples (Italy); Thomas, Philippe J. [Environment and Climate Change Canada, Science & Technology Branch, National Wildlife Research Center – Carleton University, Ottawa, Ontario, Canada K1A 0H3 (Canada); Guida, Marco [“Federico II” University of Naples, Department of Biology, I-80126 Naples (Italy); Tommasi, Franca [University of Bari, Department of Biology, Bari (Italy); Trifuoggi, Marco [“Federico II” University of Naples, Department of Chemical Sciences, I-80126 Naples (Italy)

2017-04-15

Background: Heavy rare earth elements (HREEs) have been scarcely studied for their toxicity, in spite of their applications in several technologies. Thus HREEs require timely investigations for their adverse health effects. Methods: Paracentrotus lividus and Arbacia lixula embryos and sperm were exposed to trichloride salts of five HREEs (Dy, Ho, Er, Yb and Lu) and to Ce(III) as a light REE (LREE) reference to evaluate: 1) developmental defects (% DD) in HREE-exposed larvae or in the offspring of HREE-exposed sperm; 2) mitotic anomalies; 3) fertilization success; and 4) reactive oxygen species (ROS) formation, and nitric oxide (NO) and malondialdehyde (MDA) levels. Nominal HREE concentrations were confirmed by inductively coupled plasma mass spectrometry (ICP-MS). Results: HREEs induced concentration-related DD increases in P. lividus and A. lixula larvae, ranging from no significant DD increase at 10{sup −7} M HREEs up to ≅100% DD at 10{sup −5} M HREE. Larvae exposed to 10{sup −5} M Ce(III) resulted in less severe DD rates compared to HREEs. Decreased mitotic activity and increased aberration rates were found in HREE-exposed P. lividus embryos. Significant increases in ROS formation and NO levels were found both in HREE-exposed and in Ce(III) embryos, whereas only Ce(III), but not HREEs resulted in significant increase in MDA levels. Sperm exposure to HREEs (10{sup −5}–10{sup −4} M) resulted in a concentration-related decrease in fertilization success along with increase in offspring damage. These effects were significantly enhanced for Dy(III), Ho(III), Er(III) and Yb(III), compared to Lu(III) and to Ce(III). Conclusion: HREE-associated toxicity affected embryogenesis, fertilization, cytogenetic and redox endpoints showing different toxicities of tested HREEs. - Highlights: • Different toxicities were exerted by five tested HREEs on sea urchin early life stages. • Sea urchin embryos and sperm were sensitive to HREE levels ranging from 1 to 100 �

Návrh Rail-to-Rail proudového konvejoru v technologii CMOS

OpenAIRE

Hudzik, Martin

2016-01-01

Diplomová práca sa zaoberá návrhom rail-to-rail prúdového konvejora druhej generácie v technológii CMOS. Opisuje princípy funkcie jednotlivých generácii prúdových konvejorov a taktiež základný princíp návrhu prúdového konvejora druhej generácie založeného na operačnom zosilňovači. Venuje sa obvodovému riešeniu vstupného rail-to-rail stupňa a koncového stupňa v triede AB. Cieľom tejto práce je navrhnúť, charakterizovať vlastnosti a vytvoriť topológiu prúdového konvejora druhej generácie s rail...

Low temperature specific heat of Lu-Cu-Y metallic glasses

Energy Technology Data Exchange (ETDEWEB)

Mohammed, K.A.; Lanchester, P.C.

1987-02-01

The specific heat of a series of amorphous metallic alloys of the form Lu/sub x/Cu/sub 0.37/Y/sub 0.36/ (x=0, 0.1, 0.3 and 0.4) has been measured between 2 and 50 K, primarily in order to be able to determine the non-magnetic contributions to the specific heat in magnetic Re-Cu-Y amorphous alloys. The data at low temperature fit the simple form C/sub p/=..gamma..T+..beta..T/sup 3/ from which values of ..gamma.. and theta/sub D/(0) have been determined. Consideration is given to the error that arises if Y is used rather than Lu or La in forming non-magnetic rare earth intermetallics for purposes of determining the non-magnetic contributions to the specific heat of magnetic samples. A simple procedure is described that allows a useful improvement in accuracy in estimating non-magnetic contributions below 20 K if Y is used. The method may also be useful if only a restricted range of compositions using Lu is possible.

An electro-amalgamation approach to isolate no-carrier-added {sup 177}Lu from neutron irradiated Yb for biomedical applications

Energy Technology Data Exchange (ETDEWEB)

Chakravarty, Rubel; Das, Tapas [Radiopharmaceuticals Division, Bhabha Atomic Research Centre, Mumbai 400085 (India); Dash, Ashutosh, E-mail: adash@barc.gov.i [Radiopharmaceuticals Division, Bhabha Atomic Research Centre, Mumbai 400085 (India); Venkatesh, Meera [Radiopharmaceuticals Division, Bhabha Atomic Research Centre, Mumbai 400085 (India)

2010-10-15

Introduction: A novel two-step separation process for the production of no-carrier-added (NCA) {sup 177}Lu from neutron irradiated Yb target through an electrochemical pathway employing mercury-pool cathode has been developed. Methods: A two-cycle electrolysis procedure was adopted for separation of {sup 177}Lu from {sup 177}Lu/Yb mixture in lithium citrate medium. The influence of different experimental parameters on the separation process was investigated and optimized for the quantitative deposition of Yb in presence of {sup 177}Lu. The first electrolysis was performed for 50 min in the {sup 177}Lu/Yb feed solution at pH 6 applying a potential of 8 V using platinum electrode as anode and mercury as the cathode. The second electrolysis was performed under the same conditions using fresh electrodes. The radionuclidic and chemical purity of {sup 177}Lu was determined by using gamma ray spectrometry and atomic absorption spectrometry. The suitability of {sup 177}Lu for biomedical applications was ascertained by labeling 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid D-Phe{sup 1}-Tyr{sup 3}-octreotate(DOTA-TATE) with {sup 177}Lu. Results: This process could provide NCA {sup 177}Lu with >99.99% radionuclidic purity and an overall separation yield of {approx}99% was achieved within 3-4 h. The Hg content in the product was determined to be <1 ppm. Radiolabeling yield of >98% was obtained with DOTA-TATE under the optimized reaction conditions. Conclusions: An efficient strategy for the separation of NCA {sup 177}Lu, suitable for biomedical applications, has been developed.

PENGENDALIAN DALAM PENERBITAN IZIN GANGGUAN (HO

Directory of Open Access Journals (Sweden)

Pebriana Marlinda

2017-04-01

Full Text Available Abstrak :            Penelitian tentang pengendalian dalam penerbitan izin gangguan (HO di Kecamatan Margahayu Kabupaten Bandung menjelaskan tentang tahap-tahap pengendalian yang dilakukan oleh aparat Kecamatan Margahayu. Pengendalian dilakukan untuk memastikan agar penerbitan izin gangguan (HO berjalan dengan efektif. Namun, masih ada pelaku usaha yang belum memiliki surat izin gangguan (HO ataupun pelaku usaha yang sudah memiliki surat izin gangguan (HO akan tetapi kegiatan usahanya merugkan orang lain seperti sampah yang berserakan, polusi udara, polusi suara, dan lain-lain.                            Metode penelitian yang digunakan adalah metode penelitian deduktif kualitatif dengan teknik pengumpulan data melalui studi kepustakaan dan studi lapangan yang meliputi observasi dan wawancara mendalam. Adapun penentuan informan dalam penelitian ini dipilih berdasarkan pertimbangan-pertimbangan dengan pihak-pihak yang terkait dalam pengendalian. Kemudian data yang diperoleh dari hasil wawancara dipaparkan dengan langkah-langkah yang meliputi: reduksi data, penyajian data, menarik kesimpulan/verifikasi. Teori yang digunakan penulis dalam penelitian ini adalah teori dari Stephen P. Robbins tentang tahap-tahap pengendalian yaitu: mengukur kinerja aktual, membandingkan kinerja aktual dengan standar, dan mengambil tindakan manajerial.                            Kesimpulan dari hasil penelitian ini adalah pengendalian yang dilakukan olehaparat Kecamatan Margahayu telah melalui tahap-tahap pengendalian yaitu: mengukur kinerja aktual, membandingkan kinerja aktual dengan standar, dan mengambil tindakan manajerial. Namun perlu dilakukan penguatan di setiap tahap pengendalian terutama pada tahap mengukur kinerja aktual dan pada tahap mengambil tindakan manajerial                            Penelitian tentang pengendalian dalam penerbitan izin gangguan (HO di Kecamatan

Study on preparation of 17'7Lu, labeling with DOTATATE for using in diagnosis and treatment neuroendocrine tumors

International Nuclear Information System (INIS)

Duong Van Dong; Bui Van Cuong; Pham Ngoc Dien; Chu Van Khoa; Mai Phuoc Tho; Nguyen Thi Thu; Vo Thi Cam Hoa

2014-01-01

Due to its physical and chemical characteristics, 177 Lu is a very attractive radionuclide for use in nuclear medicine. Its main usage is in the treatment of neuroendocrine tumours but its applicability in the treatment of colon cancer, metastatic bone cancer, non-Hodgkin lymphoma, lung, ovarian, and prostate cancer, has also been studied. Two alternative production routes are generally applied to obtain 177 Lu, namely the direct route based on neutron irradiation of lutetium targets and the indirect route based on neutron irradiation of ytterbium targets followed by radiochemical separation of 177 Lu from ytterbium isotopes. The comparison of theoretically calculated and experimentally determined yield for 176 Lu(n,γ) 177 Lu reaction is presented. 177 Lu could be produced with a specific activity of 42 mCi/mg by neutron activation using enriched 176 Lu (2.59%) target when irradiation was carried out at Dalat Nuclear Research Reactor with thermal neutron flux of 2x10 13 n.cm -2 .s -1 for 100 hours. The indirect production route as an alternative production route, 177 Lu could be obtained as carrier-free from beta decay of 177 Yb produced by neutron activation of 176 Yb. In this way, enriched target material was used but it may be the neutron capture cross section is only 2.4 barn so resulting in low activity just enough to study the separation process of 177 Lu from 177 Yb. In the other hand the study on labeling 177 Lu with DOTATATE is also described the optimization of the reaction conditions to obtain the complex 177 Lu-DOTATATE with a radiochemical purity > 99%, even so the studies of stability in vitro to the dilution in saline solution during 72 hours. The bio-distribution studies of this product in mice and rabbit are also investigated. (author)

The research on biodistribution of bearing sarcoma mice and rabbit SPECT imaging of 177Lu-DOTMP

International Nuclear Information System (INIS)

Deng Xinrong; Xiang Xueqin; Li Fenglin; Fan Caiyun; Liu Zihua; Luo Zhifu; Chen Yang

2012-01-01

Cyclen (1, 4, 7, 10-tetraazacyclododecane) and H 3 PO 3 were used to synthesis DOTMP (1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-Tetraaminomethylenephosphonate), and then DOTMP was labelled with 177 Lu. The research of biodistribution of 177 Lu-DOTMP in model mice bearing S180 sarcoma and SPECT imaging in Japanese white rabbit were also carried out. The results of biodistribution of bearing S180 mice indicated that 177 Lu-DOTMP cleared rapidly from blood and was selectively delivered to target bone. The radioactivity uptake was mainly in bone and less in other organs and tissues. The results of SPECT imaging of Japanese white rabbit showed that the radioactivity was accumulated in bladder. 177 Lu-DOTMP was mainly excreted by kidney. The uptake of the activity in the skeleton was observed significantly within 22 h post-injection and it became quite significant at 46 h post-injection. It indicated that 177 Lu-DOTMP has good bone targeting and is worthy of further study. (authors)

Somatostatin-based radiopeptide therapy with [177Lu-DOTA]-TOC versus [90Y-DOTA]-TOC in neuroendocrine tumours

International Nuclear Information System (INIS)

Romer, A.; Seiler, D.; Brunner, P.; Ng, Q.K.T.; Mueller-Brand, J.; Marincek, N.; Walter, M.A.; Koller, M.T.; Maecke, H.R.; Rochlitz, C.; Briel, M.; Schindler, C.

2014-01-01

Somatostatin-based radiopeptide treatment is generally performed using the β-emitting radionuclides 90 Y or 177 Lu. The present study aimed at comparing benefits and harms of both therapeutic approaches. In a comparative cohort study, patients with advanced neuroendocrine tumours underwent repeated cycles of [ 90 Y-DOTA]-TOC or [ 177 Lu-DOTA]-TOC until progression of disease or permanent adverse events. Multivariable Cox regression and competing risks regression were employed to examine predictors of survival and adverse events for both treatment groups. Overall, 910 patients underwent 1,804 cycles of [ 90 Y-DOTA]-TOC and 141 patients underwent 259 cycles of [ 177 Lu-DOTA]-TOC. The median survival after [ 177 Lu-DOTA]-TOC and after [ 90 Y-DOTA]-TOC was comparable (45.5 months versus 35.9 months, hazard ratio 0.91, 95 % confidence interval 0.63-1.30, p = 0.49). Subgroup analyses revealed a significantly longer survival for [ 177 Lu-DOTA]-TOC over [ 90 Y-DOTA]-TOC in patients with low tumour uptake, solitary lesions and extra-hepatic lesions. The rate of severe transient haematotoxicities was lower after [ 177 Lu-DOTA]-TOC treatment (1.4 vs 10.1 %, p = 0.001), while the rate of severe permanent renal toxicities was similar in both treatment groups (9.2 vs 7.8 %, p = 0.32). The present results revealed no difference in median overall survival after [ 177 Lu-DOTA]-TOC and [ 90 Y-DOTA]-TOC. Furthermore, [ 177 Lu-DOTA]-TOC was less haematotoxic than [ 90 Y-DOTA]-TOC. (orig.)

Somatostatin-based radiopeptide therapy with [177Lu-DOTA]-TOC versus [90Y-DOTA]-TOC in neuroendocrine tumours.

Science.gov (United States)

Romer, A; Seiler, D; Marincek, N; Brunner, P; Koller, M T; Ng, Q K T; Maecke, H R; Müller-Brand, J; Rochlitz, C; Briel, M; Schindler, C; Walter, M A

2014-02-01

Somatostatin-based radiopeptide treatment is generally performed using the β-emitting radionuclides (90)Y or (177)Lu. The present study aimed at comparing benefits and harms of both therapeutic approaches. In a comparative cohort study, patients with advanced neuroendocrine tumours underwent repeated cycles of [(90)Y-DOTA]-TOC or [(177)Lu-DOTA]-TOC until progression of disease or permanent adverse events. Multivariable Cox regression and competing risks regression were employed to examine predictors of survival and adverse events for both treatment groups. Overall, 910 patients underwent 1,804 cycles of [(90)Y-DOTA]-TOC and 141 patients underwent 259 cycles of [(177)Lu-DOTA]-TOC. The median survival after [(177)Lu-DOTA]-TOC and after [(90)Y-DOTA]-TOC was comparable (45.5 months versus 35.9 months, hazard ratio 0.91, 95% confidence interval 0.63-1.30, p = 0.49). Subgroup analyses revealed a significantly longer survival for [(177)Lu-DOTA]-TOC over [(90)Y-DOTA]-TOC in patients with low tumour uptake, solitary lesions and extra-hepatic lesions. The rate of severe transient haematotoxicities was lower after [(177)Lu-DOTA]-TOC treatment (1.4 vs 10.1%, p = 0.001), while the rate of severe permanent renal toxicities was similar in both treatment groups (9.2 vs 7.8%, p = 0.32). The present results revealed no difference in median overall survival after [(177)Lu-DOTA]-TOC and [(90)Y-DOTA]-TOC. Furthermore, [(177)Lu-DOTA]-TOC was less haematotoxic than [(90)Y-DOTA]-TOC.

Lattice effects in HoVo(3) single crystal

NARCIS (Netherlands)

Sikora, M.; Marquina, C.; Ibarra, M. R.; Nugroho, A. A.; Palstra, T. T. M.

We report the study of lattice effects in the Mott insulator HoVO3 performed by means of linear thermal expansion on a single crystal in the temperature range 10-290 K. The holmium orthovanadate HoVO3 reveals gradual orbital ordering (OO) below T-OO = 200K and orders antiferromagnetically at T-N =

{sup 166}Ho-chitosan as a radiation synovectomy agent - biocompatibility study of {sup 166}Ho-chitosan in rabbits

Energy Technology Data Exchange (ETDEWEB)

Kim, Sug Jun; Lee, Soo Yong; Jeon, Dae Geun; Seok, Lee Jong [Korea Cancer Center Hospital, Seoul (Korea, Republic of)

1997-01-01

Radiation synovectomy is a noninvasive therapy that has been investigated as an alternative to surgical synovectomy. It is been successfully employed in the treatment of synovitis in rheumatoid arthrits and other inflammatory arthropathies. We developed the {sup 166}Ho-chitosan complex for possible use as a radiation synovectomy agent. Holmium is the more practical isotope based on its higher radioactivity and logner half-life. And isotope based on its higher radioactivity and logner half-life. And chitosan is ideal and suitable particles based on its soluble and biodegradable characteristics. So we investigated the biocompatibility of the {sup 166}Ho-chitosan complex to evaluated the suitability as a radiation synovectomy agent. In this study, we performed in vivo and in vitro stability test and biodistribution test. Our results indicate that {sup 166}Ho-chitosan may be an effective radiopharmaceutical for radiation synovectomy. (author). 30 refs., 7 tabs.

Crystal growth and luminescence properties of Pr-doped LuLiF4 single crystal

International Nuclear Information System (INIS)

Sugiyama, Makoto; Yanagida, Takayuki; Yokota, Yuui; Kurosawa, Shunsuke; Fujimoto, Yutaka; Yoshikawa, Akira

2013-01-01

0.1, 1, and 3% Pr (with respect to Lu) doped LuLiF 4 (Pr:LuLiF 4 ) single crystals were grown by the micro-pulling-down (μ-PD) method. Transparency of the grown crystals was higher than 70% in the visible wavelength region with some absorption bands due to Pr 3+ 4f-4f transitions. Intense absorption bands related with the Pr 3+ 4f-5d transitions were observed at 190 and 215 nm. In radioluminescence spectra, Pr 3+ 5d-4f emissions were observed at 220, 240, 340, and 405 nm. In the pulse height spectra recorded under 137 Cs γ-ray excitation, the Pr 3% doped sample showed the highest light yield of 2050 photons/MeV and the scintillation decay time of it exhibited 23 and 72 ns also excited by 137 Cs γ-ray. -- Highlights: ► 0.1, 1, and 3% Pr-doped LuLiF 4 single crystals were grown by the μ-PD method. ► Pr 3+ 5d-4f emission peaks appeared at 220, 240, 340, and 405 nm ► The Pr 3%:LuLiF 4 crystal showed the highest light yield of 2050 photons/MeV

Politik er ikke lykken

DEFF Research Database (Denmark)

Steenbuch, Johannes Aakjær

2011-01-01

Der er ikke længere nogen højere sandhed i livet end den, flertallet bestemmer sig for – og dermed ingen del af livet, der ikke er politisk. Højre- og venstrefløjen er i bund og grund enige - enige om, at det er politikernes opgave at forære os det gode liv. Dermed bliver demokratiet totalitært. ...

Magnetic ordering in Sc{sub 2}CoSi{sub 2}-type R{sub 2}FeSi{sub 2} (R=Gd, Tb) and R{sub 2}CoSi{sub 2} (R=Y, Gd–Er) compounds

Energy Technology Data Exchange (ETDEWEB)

Morozkin, A.V., E-mail: morozkin@tech.chem.msu.ru [Department of Chemistry, Moscow State University, Leninskie Gory, House 1, Building 3, GSP-2, Moscow 119992 (Russian Federation); Knotko, A.V. [Department of Chemistry, Moscow State University, Leninskie Gory, House 1, Building 3, GSP-2, Moscow 119992 (Russian Federation); Yapaskurt, V.O. [Department of Petrology, Geological Faculty, Moscow State University, Leninskie Gory, Moscow 119992 (Russian Federation); Pani, M. [Department of Chemistry, University of Genova, Via Dodecaneso 31, 16146 Genova (Italy); Institute SPIN-CNR, C. Perrone 24, 16152 Genova (Italy); Nirmala, R. [Indian Institute of Technology Madras, Chennai 600036 (India); Quezado, S.; Malik, S.K. [Departamento de Física Teórica e Experimental, Universidade Federal do Rio Grande do Norte, Natal 59082-970 (Brazil)

2016-09-01

Magnetic and magnetocaloric properties of Sc{sub 2}CoSi{sub 2}-type R{sub 2}TSi{sub 2} (R=Gd–Er, T=Fe, Co) compounds have been studied using magnetization data. These indicate the presence of mixed ferromagnetic and antiferromagnetic interactions in these compounds. One observes a ferromagnetic transition followed by an antiferromagnetic order and a further possible spin-reorientation transition at low temperatures. Compared to Gd{sub 2}{Fe, Co}Si{sub 2}, the Tb{sub 2}FeSi{sub 2} and {Tb–Er}{sub 2}CoSi{sub 2} compounds exhibit remarkable hysteresis (for e.g. Tb{sub 2}FeSi{sub 2} shows residual magnetization M{sub res}/Tb=2.45 μ{sub B}, coercive field H{sub coer}=14.9 kOe, and critical field H{sub crit}~5 kOe at 5 K) possibly due to the magnetocrystalline anisotropy of the rare earth. The R{sub 2}{Fe, Co}Si{sub 2} show relatively small magnetocaloric effect (i.e. isothermal magnetic entropy change, ΔS{sub m}) around the magnetic transition temperature: the maximal value of MCE is demonstrated by Ho{sub 2}CoSi{sub 2} (ΔS{sub m}=−8.1 J/kg K at 72 K and ΔS{sub m}=−9.4 J/kg K at 23 K in field change of 50 kOe) and Er{sub 2}CoSi{sub 2} (ΔS{sub m}=−13.6 J/kg K at 32 K and ΔS{sub m}=−8.4 J/kg K at 12 K in field change of 50 kOe). - Highlights: • {Gd–Er}{sub 2}{Fe, Co}Si{sub 2} show high-temperature ferromagnetic-type transitions. • {Gd–Er}{sub 2}{Fe, Co}Si{sub 2} show low-temperature spin-reorientation transitions. • Tb{sub 2}FeSi{sub 2} and {Tb–Er}{sub 2}CoSi{sub 2} compounds exhibit low-temperature hysteresis. • Tb{sub 2}FeSi{sub 2} shows M{sub res}/Tb=2.45 μ{sub B}, H{sub coer}=14.9 kOe and H{sub crit} ~5 kOe at 5 K • Considerable magnetocaloric effect is exhibited by Ho{sub 2}CoSi{sub 2} and Er{sub 2}CoSi{sub 2}.

A database of astrophysical interest covering the UV region

International Nuclear Information System (INIS)

Biemont, E.; Quinet, P.; University of Mons-Hainaut

2004-01-01

Full text: Our knowledge of the spectra of the rare-earths is still very poor due to the fragmentary laboratory analyses on the one hand and to the complexity of the configurations involving unfilled 4f shells on the other hand. The aim of the database DREAM is to supply the astrophysicists and the physicists with accurate atomic data (wave- lengths, energy levels, oscillator strengths, radiative lifetimes) of neutral, singly or multiply ionized lanthanides. Calculations of atomic structures and spectra in heavy ions like the lanthanides are frequently the only way to obtain the large amount of atomic data required by astrophysics, particularly for the analysis of the spectra of chemically peculiar stars. Such calculations, extremely complex, need to be tested by comparisons with experiment in order to deduce some information about their predictive power. For that reason, we have systematically compared the results obtained with our theoretical models (HFR approach including core-polarisation effects) with new lifetime measurements carried out with time-resolved laser-induced fluorescence laser techniques (collaboration with the Lund Laser Center in Sweden). The database DREAM (Database on Rare-Earths at Mons University) contains presently data for over 60 000 transitions and is continuously updated. The different tables, which cover the UV, the visible and near infrared regions, are located on the web page: http://www.umh.ac.be/ astro/dream.shtm. Up to now data are tabulated for the following ions : La III, Ce II, Ce III, Pr II, Pr III, Nd II, Nd III, Sm II, Sm III, Eu III, Gd III, Tb III, Dy III, Ho III, Er II, Er III, Tm II, Tm III, Yb II, Yb III, Yb IV, Lu I, Lu II and Lu III. Some information is also provided for Th III. All the references (about 40 papers), summarizing and discussing the new experimental and theoretical results obtained during the past few years, are given on this web site. Some specific examples of the results obtained will be discussed at

Optical characteristics of BaGa{sub 2}S{sub 4}:Ho{sup 3+} and BaGa{sub 2}Se{sub 4}:Ho{sup 3+} single crystals

Energy Technology Data Exchange (ETDEWEB)

Choe, Sung-Hyu [Chosun University, Kwangju (Korea, Republic of); Jin, Moon-Seog [Dongshin University, Naju (Korea, Republic of); Kim, Wha-Tek [Chonnam National University, Kwangju (Korea, Republic of)

2005-11-15

BaGa{sub 2}S{sub 4}, BaGa{sub 2}S{sub 4}:Ho{sup 3+}, BaGa{sub 2}Se{sub 4}, and BaGa{sub 2}Se{sub 4}:Ho{sup 3+} single crystals were grown by using the chemical transport reaction method. The optical energy gaps of the single crystals were investigated in the temperature region from 11 K to 300 K. The temperature dependence of the optical energy gap was well fitted by the Varshni equation. Two broad emission bands were observed in the photoluminescence spectra of the single crystals. These bands were attributed to donor-acceptor pair recombinations. Sharp emission peaks were observed in the BaGa{sub 2}S{sub 4}:Ho{sup 3+} and the BaGa{sub 2}Se{sub 4}:Ho{sup 3+} single crystals and were assigned to radiation recombination between split Stark levels of Ho{sup 3+}.

The mass of the electron neutrino and electron capture in 163Ho

International Nuclear Information System (INIS)

Yasumi, S.; Rajasekaran, G.; Ando, M.; Ochiai, F.; Ikeda, H.; Ohta, T.; Stefan, P.M.; Maruyama, M.; Nashimoto, N.; Fujioka, M.; Ishii, K.; Shinozuka, T.; Sera, K.; Omori, T.; Izawa, G.; Yagi, M.; Masumoto, K.; Shima, K.

1983-01-01

To determine the mass of the electron neutrino, electron capture in 163 Ho was studied. From the intensity of M X-rays and the total number of 163 Ho atoms in a source, as determined by the PIXE method, the partial M-capture half life of 163 Ho was estimated to be (4.5 +- 1.5) x 10 4 yr. A relation between the Q-value of 163 Ho and the mass of the electron neutrino was obtained. (orig.)

Diode-Pumped Thulium (Tm)/Holmium (Ho) Composite Fiber 2.1-Micrometers Laser

Science.gov (United States)

2015-09-01

Schematic of the 800-nm diode pumped Tm/Ho composite fiber laser 8 Under quasi-continuous wave (Q- CW ) pumping conditions of 1-ms duration and a...Fig. 9 (Top) Schematic of the 800-nm diode -pumped Tm/Ho composite fiber laser with outcoupler. (Left) Q- CW laser performance of the Tm/Ho composite...ARL-TR-7452 ● SEP 2015 US Army Research Laboratory Diode -Pumped Thulium (Tm)/Holmium (Ho) Composite Fiber 2.1-μm Laser by G

ON LU FACTORIZATION ALGORITHM WITH MULTIPLIERS

African Journals Online (AJOL)

Various algorithm such as Doolittle, Crouts and Cholesky's have been proposed to factor a square matrix into a product of L and U matrices, that is, to find L and U such that A = LU; where L and U are lower and upper triangular matrices respectively. These methods are derived by writing the general forms of L and U and the ...

Flood-Inundation maps for the Hohokus Brook in Waldwick Borough, Ho-Ho-Kus Borough, and the Village of Ridgewood, New Jersey, 2014

Science.gov (United States)

Watson, Kara M.; Niemoczynski, Michal J.

2015-07-20

Digital flood-inundation maps for a 6-mile reach of the Hohokus Brook in New Jersey from White's Lake Dam in Waldwick Borough, through Ho-Ho-Kus Borough to Grove Street in the Village of Ridgewood were created by the U.S. Geological Survey (USGS) in cooperation with the New Jersey Department of Environmental Protection. The flood inundation maps, which can be accessed through the USGS Flood Inundation Mapping Science Web site at http://water.usgs.gov/osw/flood_inundation, depict estimates of the areal extent and depth of flooding corresponding to selected water levels (stages) at the USGS streamgage on the Hohokus Brook at Ho-Ho-Kus, New Jersey (station number 01391000). Stage data at this streamgage may be obtained on the Internet from the USGS National Water Information System at http://waterdata.usgs.gov/nwis/uv?site_no=01391000 or the National Weather Service (NWS) Advanced Hydrologic Prediction Service at http://water.weather.gov/ahps2/hydrograph.php?gage=hohn4&wfo=okx.

Potential renal toxicity bio-markers indicating radiation injury after 177Lu-octreotate treatment

International Nuclear Information System (INIS)

Dalmo, J.; Forssell-Aronsson, E.; Westberg, E.; Toernqvist, M.; Svedborn, L.; Barregaerd, L.

2015-01-01

Full text of publication follows. The kidneys are one of the most exposed non-tumor tissues and regarded as one of the main dose-limiting organs in peptide receptor radionuclide therapy (PRRT). [ 177 Lu-DOTA0, Tyr3]-octreotate ( 177 Lu-octreotate) has shown promising results in the treatment of somatostatin receptor over-expressing neuroendocrine tumors, but optimization is still needed. The ability to give each patient as much 177 Lu-octreotate as possible without inducing nephrotoxicity is necessary for an efficient treatment. However, due to large inter-individual differences in uptake and retention in the kidneys, there is a need for efficient methods that can indicate renal injury early. A possible way is to identify bio-markers for high risk of radiation nephrotoxicity. The aim of this study was to investigate the potential of using urinary retinol binding protein (RBP), and blood valinhydantoin (VH) as bio-markers of nephrotoxicity on adult mice after 177 Lu-octreotate treatment. BALB/c nude mice (n=6/group) were i.v. injected with 60 MBq or 120 MBq of 177 Lu-octreotate. The control group was mock treated with saline. Spot urine samples were collected before injection, and 14, 30, 60 and 90 days after injection. Analysis of RBP4 and creatinine was performed using Mouse RBP4 ELISA kit and Creatinine kit from R/D Systems, respectively. Erythrocytes were separated from whole blood samples collected 90 days after injection, and analysed for VH by LC-MS/MS. The ratio between VH and a volumetric standard was calculated. The RBP/creatinine level increased with time in both groups given 177 Lu-octreotate, with earlier and higher response for the 120 MBq group. No clear change in VH level between the different groups was observed. The results show that RBP may be a promising new bio-marker for radiation induced kidney toxicity. The presently used method based on VH was not sensitive enough to be used as kidney toxicity marker. Further studies on mice are ongoing to

Overall survival and response pattern of castration-resistant metastatic prostate cancer to multiple cycles of radioligand therapy using [177Lu]Lu-PSMA-617.

Science.gov (United States)

Ahmadzadehfar, Hojjat; Wegen, Simone; Yordanova, Anna; Fimmers, Rolf; Kürpig, Stefan; Eppard, Elisabeth; Wei, Xiao; Schlenkhoff, Carl; Hauser, Stefan; Essler, Markus

2017-08-01

Up to 30% of patients with castration-resistant prostate cancer (CRPC) do not show any response to the first cycle of radioligand therapy (RLT) with [ 177 Lu]Lu-PSMA-617 (Lu-PSMA). We evaluated patient response to the second and third cycles of RLT in patients that underwent at least three cycles. The second aim of this study was to calculate the median overall survival (OS) of responders and non-responders after the first cycle and after all three cycles of RLT. CRPC patients were treated with Lu-PSMA, with a median interval of 8 weeks between each cycle. The tumour marker prostate-specific antigen (PSA) was used as the marker for response evaluation. Fifty-two patients underwent a total of 190 cycles of RLT (3-6 cycles per patient). Of these, 80.8% showed a decline in PSA 2 months after the first cycle, with 44.2% showing a PSA decline of ≥50%. When compared to baseline PSA, 73.1% showed a PSA decline after the third cycle. 50% of patients that did not show any response to the first cycle also did not respond to the second and third cycles. The median OS was 60 weeks in all patients. The median OS was significantly longer for patients that showed any PSA decline after the first cycle compared to patients without PSA decline (68 vs. 33 weeks). There was a significant difference in median OS between responders and non-responders for a change in PSA after the third cycle compared to baseline PSA. Patients with a positive response to RLT, regardless of the rate of decline, had a significantly longer median OS. Of the patients that did not show any response to the first cycle, 50% responded to the second or third cycles.

The uptake of HO2 radicals to organic aerosols

Science.gov (United States)

Matthews, Pascale; Krapf, Manuel; Dommen, Josef; George, Ingrid; Whalley, Lisa; Ingham, Trevor; Baeza-Romero, Maria Teresa; Ammann, Markus; Heard, Dwayne

2014-05-01

HOx (OH + HO2) radicals are responsible for the majority of the oxidation in the troposphere and control the concentrations of many trace species in the atmosphere. There have been many field studies where the measured HO2 concentrations have been smaller than the concentration predicted by model calculations [1,2]. The difference has often been attributed to HO2 uptake by aerosols. Organics are a major component of aerosols accounting for 10 - 70 % of their mass [3]. However, there have been very few laboratory studies measuring HO2 uptake onto organic aerosols [4]. Uptake coefficients (γ) were measured for a range of aerosols using a Fluorescence Assay By Gas Expansion (FAGE) detector combined with an aerosol flow tube. HO2 was injected into the flow tube using a moveable injector which allowed first order HO2 decays to be measured along the flow tube both with and without aerosols. Laboratory generated aerosols were made using an atomiser or by homogeneous nucleation. Secondary organic aerosols (SOA) were made using the Paul Scherrer Institute smog chamber and also by means of a Potential Aerosol Mass (PAM) chamber. The total aerosol surface area was then measured using a Scanning Mobility Particle Sizer (SMPS). Experiments were carried out on aerosols containing glutaric acid, glyoxal, malonic acid, stearic acid, oleic acid and squalene. The HO2 uptake coefficients for these species were measured in the range of γ contained elevated levels of transition metal ions. For humic acid the uptake coefficient was highly dependent on humidity and this may be explained by the liquid water content of the aerosols. Measurements were also performed on copper doped aerosols containing different organics. An uptake coefficient of 0.23 ± 0.07 was measured for copper doped ammonium sulphate, however, this was reduced to 0.008 ± 0.009 when EDTA was added in a 1:1 ratio with copper and 0.003 ± 0.004 when oxalic acid was added in a 10:1 ratio with copper. SOA aerosols were

L'U. Una història de família

OpenAIRE

Montserrat i Torrents, Josep

1994-01-01

El fals problema de l'U. Les nocions connexes d'ordre i d'unitat es troben presents ja en el pensament quodidià. Un moble tan familiar com un armari ofereix un feix de suggerències metafísiques sobre les coses, el lloc de les coses i els noms dels llocs de les coses. Agustí pensava probablement en l'armari de la seva mare quan proposà la seva bella definició d'ordre: ordo est parium disparium que rerum suo cuique loco tribuens dispositio. Filosòficament, l'U comparegué amb agressivitat ...

The regulation of prostitution in Beyoğlu (1875-1915).

Science.gov (United States)

özbek, Müge

2010-01-01

This study examines the development and nature of the regulation of prostitution in Beyoğlu during the late Ottoman Empire with special emphasis on the way the regulationist regime reinforced existing patterns of class and gender domination. The regulation of prostitution became a matter of urgency in the last decades of the nineteenth century in Istanbul, particularly in Beyoğlu, the cosmopolitan centre of the city. Through this process, the protests of the local residents of the area objecting to the proliferation of prostitution in their neighbourhoods played a crucial role in prompting the governmental authorities to tighten the regulations.

Predicted energetics and properties of rare-earth ferrites films grown on cubic (1 1 1)- and hexagonal (0 0 0 1)-oriented substrates

International Nuclear Information System (INIS)

Zhao, Hong Jian; Chen, Xiang Ming; Xu, Changsong; Duan, Wenhui; Yang, Yurong; Bellaiche, L

2015-01-01

First-principles calculations are performed to compare the energetics of several phases, including hexagonal polar P6 3 cm and perovskite non-polar Pbnm-like states, of epitaxial RFeO 3 films (with R  =  Ce, Pr, Nd, Sm, Gd, Tb, Dy, Ho, Er and Lu) grown on different cubic (1 1 1)- and hexagonal (0 0 0 1)-oriented substrates. The P6 3 cm phase is found to be the ground state for large enough in-plane lattice parameters in all investigated RFeO 3 films, and its polarization is tunable by the amount of epitaxial strain. Series of available substrates allowing the growth of hexagonal polar RFeO 3 films, as well as other phenomena of fundamental and technological importance (e.g. different ground states and coexistence between several phases) are also predicted. (paper)

Intercalation of lanthanide trichlorides in graphite

International Nuclear Information System (INIS)

Stumpp, E.; Nietfeld, G.

1979-01-01

The reactions of the whole series of lanthanide trichlorides with graphite have been investigated. Intercalation compounds have been prepared with the chlorides of Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, Sc, Y whereas LaCl 3 , CeCl 3 , PrCl 3 and NdCl 3 do not intercalate. The compounds were characterized by chemical and X-ray analysis. The amount of c-axis increase is consistent with the assumption that the chlorides are intercalated in form of a chloride layer sandwich resmbling the sheets in YCl 3 . The chlorides which do not intercalate crystallize in the UCl 3 structure having 3 D arrangements of ions. Obviously, these chlorides cannot form sheets between the carbon layers. The ability of AlCl 3 to volatilize lanthanide chlorides through complex formation in the gas phase can be used to increase the intercalation rate strikingly. (author)

Surface shift of the occupied and unoccupied 4f levels of the rare-earth metals

DEFF Research Database (Denmark)

Aldén, Magnus; Johansson, Börje; Skriver, Hans Lomholt

1995-01-01

The surface energy shifts of the occupied and unoccupied 4f levels for the lanthanide metals have been calculated from first principles by means of a Green’s-function technique within the tight-binding linear muffin-tin orbitals method. We use the concept of complete screening to identify...... the occupied and unoccupied 4f energy level shifts as the surface segregation energy of a 4fn-1 and 4fn+1 impurity atom, respectively, in a 4fn host metal. The calculations include both initial- and final-state effects and give values that are considerably lower than those measured on polycrystalline samples...... as well as those found in previous initial-state model calculations. The present theory agrees well with very recent high-resolution, single-crystal film measurements for Gd, Tb, Dy, Ho, Er, Tm, and Lu. We furthermore utilize the unique possibility offered by the lanthanide metals to clarify the roles...

X-ray fluorescence analysis of erbium oxide/oxalate for rare earth impurities

International Nuclear Information System (INIS)

Chandola, L.C.; Khanna, P.P.; Thomas, A.

1981-01-01

A method for the determination of Tb, Dy, Ho, Tm, Yb, Lu and Y oxides in Er 2 O 3 is described. 450 mg sample in the oxalate form is mixed with 150 mg boric acid binding material and pressed into a 1.25 inch diameter pellet over a supporting pellet of boric acid. The sample is then irradiated by X-rays from a tungsten tube and the fluorescent X-rays are dispersed by a LiF (200) crystal in a Philips PW 1220 semiautomatic X-ray fluorescence spectrometer. The intensities of characteristic X-rays of the impurity elements are measured by a flow proportional counter for all elements except yttrium for which the intensities are measured by a scintillation counter. The lowest determination limit is 0.005% for all impurities except for Yb for which it is 0.01%. Calculations for theoretical detection limit are given. (author)

Series of chiral interpenetrating 3d-4f heterometallic MOFs: Luminescent sensors and magnetic properties

Science.gov (United States)

Zhang, Xiaolei; Chen, Chen; Liu, Xiaoli; Gao, Peng; Hu, Ming

2017-09-01

Series of chiral 3d-4f heterometallic MOFs based on a multidentate terpyridyl carboxylic acid ligand have been synthesized under the solvothermal conditions, namely, [LnZnL(CO3)2(H2O)]n (Ln = Eu (1), Gd (2), Dy (3), Ho (4), Er (5), Tm (6), Yb (7), Lu (8)) (HL = 4‧-(4-carboxyphenyl)-2,2‧:6‧,2″-terpyridine). Compounds 1-8 were structurally characterized by the elemental analyses, infrared spectra, and single crystal X-ray diffractions. Compounds 1-8 exhibit the chiral interpenetrating 3D frameworks. Interestingly, 1 can serve as the luminescent sensor to detect nitrobenzene molecules with high sensitivity. The investigations on CD spectra of single crystals clearly assigned the Cotton effect, indicating that there exist two chiral enantiomers of 1-8 in the course of crystallization. The magnetic properties of 2 and 7 were exploited, respectively.

Rare earth element distribution and behaviour in buried manganese nodules from the Central Indian Basin

Digital Repository Service at National Institute of Oceanography (India)

Pattan, J.N.; Banakar, V.K.

.43 1.34 1.36 1.55 0.60 0.17 4977 5620 716 1746 1095 348 8 Siliceous 4.34 2.02 0.60 0.19 0.66 2.10 1.22 1.15 0.13 256 184 119 59 48 1.4 23 ooze* Buried Ba Y La Ce Nd Sm Eu Gd Dy Ho Er Yb Lu Ce # depth (cm) Surface* 1639 104 119 455 139 30.0 7.2 29....27 92.5 1416 101 80 492 86 19.1 4.5 20.6 17.0 3.1 8.5 8.0 1.4 0.46 Siliceous 2229 45 35 94 42 11.3 2.7 10.3 9.7 1.8 5.2 4.8 0.8 0.08 ooze* * sediment-nodule pair from the surface of SK-176 core. Ce # Ce anomaly = log \\[ Ce(2/3 La + I/3 Nd)\\], based...

A comparison of SuperLU solvers on the intel MIC architecture

Science.gov (United States)

Tuncel, Mehmet; Duran, Ahmet; Celebi, M. Serdar; Akaydin, Bora; Topkaya, Figen O.

2016-10-01

In many science and engineering applications, problems may result in solving a sparse linear system AX=B. For example, SuperLU_MCDT, a linear solver, was used for the large penta-diagonal matrices for 2D problems and hepta-diagonal matrices for 3D problems, coming from the incompressible blood flow simulation (see [1]). It is important to test the status and potential improvements of state-of-the-art solvers on new technologies. In this work, sequential, multithreaded and distributed versions of SuperLU solvers (see [2]) are examined on the Intel Xeon Phi coprocessors using offload programming model at the EURORA cluster of CINECA in Italy. We consider a portfolio of test matrices containing patterned matrices from UFMM ([3]) and randomly located matrices. This architecture can benefit from high parallelism and large vectors. We find that the sequential SuperLU benefited up to 45 % performance improvement from the offload programming depending on the sparse matrix type and the size of transferred and processed data.

Structure of wobbling excitations in 163Lu

International Nuclear Information System (INIS)

Carlsson, B.G.

2007-01-01

Using a many-particles plus rotor model, wobbling excitations built on top of a triaxial superdeformed band in 163 Lu are investigated. By extracting all parameters for the rotor from a mean field calculation a good correspondence with calculations based on the random-phase approximation is achieved. (author)

Scintillation properties of YAlO3 doped with Lu and Nd perovskite single crystals

Science.gov (United States)

Akatsuka, Masaki; Usui, Yuki; Nakauchi, Daisuke; Kato, Takumi; Kawano, Naoki; Okada, Go; Kawaguchi, Noriaki; Yanagida, Takayuki

2018-05-01

YAlO3 (YAP) single crystals doped with Lu and Nd were grown by the Floating Zone (FZ) method to evaluate their scintillation properties particularly emissions in the near-infrared (NIR) range. The Nd concentration was fixed to 0 or 1 mol% while the Lu concentration was varied from 0 to 30%. When X-ray was irradiated, the scintillation of Nd-doped samples was observed predominantly at 1064 nm due to 4F3/2 → 4I11/2 transition of Nd3+. In contrast, a weak emission around 700 nm appeared in the samples doped with only Lu, and the emission origin was attributed to defect centers. In the Nd3+-doped samples, the decay time was 94-157 μs due to the 4f-4f transitions of Nd3+ whereas the Lu-doped samples showed signal with the decay time of 1.45-1.54 ms. The emission origin of the latter signal was attributed to the perovskite lattice defect.

Phase stabilization in transparent Lu2O3:Eu ceramics by lattice expansion

Science.gov (United States)

Seeley, Z. M.; Dai, Z. R.; Kuntz, J. D.; Cherepy, N. J.; Payne, S. A.

2012-11-01

Gadolinium lutetium oxide transparent ceramics doped with europium (Gd,Lu)2O3:Eu were fabricated via vacuum sintering and hot isostatic pressing (HIP). Nano-scale starting powder with the composition GdxLu1.9-xEu0.1O3 (x = 0, 0.3, 0.6, 0.9, 1.0, and 1.1) were uniaxially pressed and sintered under high vacuum at 1625 °C to obtain ˜97% dense structures with closed porosity. Sintered compacts were then subjected to 200 MPa argon gas at temperatures between 1750 and 1900 °C to reach full density. It was observed that a small portion of the Eu3+ ions were exsolved from the Lu2O3 cubic crystal lattice and concentrated at the grain boundaries, where they precipitated into a secondary monoclinic phase creating optical scattering defects. Addition of Gd3+ ions into the Lu2O3 cubic lattice formed the solid solution (Gd,Lu)2O3:Eu and stretched the lattice parameter allowing the larger Eu3+ ions to stay in solid solution, reducing the secondary phase and improving the transparency of the ceramics. Excess gadolinium, however, resulted in a complete phase transformation to monoclinic at pressures and temperatures sufficient for densification. Light yield performance was measured and all samples show equal amounts of the characteristic Eu3+ luminescence, indicating gadolinium addition had no adverse effect. This material has potential to improve the performance of high energy radiography devices.

Neutron activation analysis of NBS oyster tissue (SRM 1566) and IAEA animal bone (H-5)

International Nuclear Information System (INIS)

Lepel, E.A.; Laul, J.C.

1983-10-01

Data have been presented for 35 elements determined by INAA for NBS oyster tissue (SRM 1566) and for 38 elements determined by INAA and RNAA for IAEA animal bone (H-5). The experimental data showed excellent agreement with published values wherever the comparison exists. Additional trace-element data in the ppb range have been presented for the elements Sc, Sb, Cs, La, Ce, Nd, Sm, Eu, Tb, Dy, Ho, Yb, Lu, Hf, Ta, W and Th in NBS oyster tissue. Also, additional trace-element data for IAEA animal bone (H-5) in the ppb range for the elements Al, Sc, Co, Rb, Cs, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Tm, Yb, lu, Hf, Ta and Th have been presented

68Ga/177Lu-labeled DOTA-TATE shows similar imaging and biodistribution in neuroendocrine tumor model.

Science.gov (United States)

Liu, Fei; Zhu, Hua; Yu, Jiangyuan; Han, Xuedi; Xie, Qinghua; Liu, Teli; Xia, Chuanqin; Li, Nan; Yang, Zhi

2017-06-01

Somatostatin receptors are overexpressed in neuroendocrine tumors, whose endogenous ligands are somatostatin. DOTA-TATE is an analogue of somatostatin, which shows high binding affinity to somatostatin receptors. We aim to evaluate the 68 Ga/ 177 Lu-labeling DOTA-TATE kit in neuroendocrine tumor model for molecular imaging and to try human-positron emission tomography/computed tomography imaging of 68 Ga-DOTA-TATE in neuroendocrine tumor patients. DOTA-TATE kits were formulated and radiolabeled with 68 Ga/ 177 Lu for 68 Ga/ 177 Lu-DOTA-TATE (M-DOTA-TATE). In vitro and in vivo stability of 177 Lu-DOTA-TATE were performed. Nude mice bearing human tumors were injected with 68 Ga-DOTA-TATE or 177 Lu-DOTA-TATE for micro-positron emission tomography and micro-single-photon emission computed tomography/computed tomography imaging separately, and clinical positron emission tomography/computed tomography images of 68 Ga-DOTA-TATE were obtained at 1 h post-intravenous injection from patients with neuroendocrine tumors. Micro-positron emission tomography and micro-single-photon emission computed tomography/computed tomography imaging of 68 Ga-DOTA-TATE and 177 Lu-DOTA-TATE both showed clear tumor uptake which could be blocked by excess DOTA-TATE. In addition, 68 Ga-DOTA-TATE-positron emission tomography/computed tomography imaging in neuroendocrine tumor patients could show primary and metastatic lesions. 68 Ga-DOTA-TATE and 177 Lu-DOTA-TATE could accumulate in tumors in animal models, paving the way for better clinical peptide receptor radionuclide therapy for neuroendocrine tumor patients in Asian population.

Isolation of {sup 163}Ho from dysprosium target material by HPLC for neutrino mass measurements

Energy Technology Data Exchange (ETDEWEB)

Mocko, Veronika; Taylor, Wayne A.; Nortier, Francois M.; Engle, Jonathan W.; Pollington, Anthony D.; Kunde, Gerd J.; Rabin, Michael W.; Birnbaum, Eva R. [Los Alamos National Laboratory, Los Alamos, NM (United States). Chemistry Div.; Barnhart, Todd E.; Nickles, Robert J. [Univ. Wisconsinn, Madison, WI (United States). Dept. of Medical Physics

2015-07-01

The rare earth isotope {sup 163}Ho is of interest for neutrino mass measurements. This report describes the isolation of {sup 163}Ho from a proton-irradiated dysprosium target and its purification. A Dy metal target was irradiated with 16 MeV protons for 10 h. After target dissolution, {sup 163}Ho was separated from the bulk Dy via cation-exchange high performance liquid chromatography using 70 mmol dm{sup -3} α-hydroxyisobutyric acid as the mobile phase. Subsequent purification of the collected Ho fraction was performed to remove the α-hydroxyisobutyrate chelating agent and to concentrate the Ho in a low ionic strength aqueous matrix. The final solution was characterized by MC-ICP-MS to determine the {sup 163}Ho/{sup 165}Ho ratio, {sup 163}Ho and the residual Dy content. The HPLC purification process resulted in a decontamination factor 1.4 x 10{sup 5} for Dy. The isolated Ho fraction contained 24.8 ± 1.3 ng of {sup 163}Ho corresponding to holmium recovery of 72 ± 3%.

Mechanické vlastnosti slitiny AlSi9Cu3 zpracovaného technologií SLM

OpenAIRE

Koutný, Filip

2017-01-01

Tato bakalářská práce se zabývá porovnáním mechanických vlastností hliníkové slitiny AlSi9Cu3 v odlitém stavu se stavem po zpracování technologií selective laser melting (SLM). Rešeršní část práce pojednává o problematice hliníkových slitin, především o jejich rozdělení, mechanických vlastnostech, tepelné úpravě a zpracování technologií SLM. V diskuzi je řešen návrh optimálního rozsahu procesních parametrů SLM tisku a jsou porovnány mechanické vlastnosti konvenčně odlité slitiny AlSi9Cu3 se s...

FAGE measurements of tropospheric HO with measurements and model of interferences

Science.gov (United States)

Hard, T. M.; Mehrabzadeh, A. A.; Chan, C. Y.; O'Brien, R. J.

1992-01-01

Ambient HO measurements by low-pressure laser-excited fluorescence with chemical modulation, and supporting ozone and water-vapor data, are presented for periods in May and August 1987. The observed peak daytime ambient HO concentrations are in the range (2.5 to 8) x 10 exp 6 molecules/cu cm and show small negative offsets due to photochemical interference. Direct measurements of the interference at fixed (O3) give the dependence on ambient (H2O) and on the modulating reagent (isobutane). At ambient (O3) = 30 ppb and 10 torr H2O, with excitation and detection at a total pressure of 4 torr, the net interference is equal to (HO) = -1.3 x 10 exp 6 molecules/cu cm. Production of HO by the reaction of isobutane with O(1D) accounts for the negative interference. Quenching of HO fluorescence by the modulating reagent contributes a smaller positive term to the interference; kinetic measurements of the quenching rate coefficient are reported. The experimental interference results are compared with a detailed kinetic model of HO production, excitation, relaxation, and detection; reasonable agreement is found.

Demonstration of a hybrid Ho:YLF Ho:LuLF slab laser

CSIR Research Space (South Africa)

Esser, MJD

2010-10-01

Full Text Available % at 2 ?m were selected as output couplers. The hybrid stable-unstable resonator configuration utilised a cylindrical mirror of curvature r = 449 mm in position M4 and a knife-edge mirror to couple out the laser beam. In both configurations the total...

Third-line treatment and {sup 177}Lu-PSMA radioligand therapy of metastatic castration-resistant prostate cancer: a systematic review

Energy Technology Data Exchange (ETDEWEB)

Edler von Eyben, Finn [Center of Tobacco Control Research, Odense (Denmark); Roviello, Giandomenico [San Donato Hospital, Department of Oncology, Medical Oncology Unit, Arezzo (Italy); University of Trieste, Department Medical, Surgery, and Health Sciences, Trieste (Italy); Kiljunen, Timo; Kairemo, Kalevi; Joensuu, Timo [Docrates Cancer Center, Helsinki (Finland); Uprimny, Christian; Virgolini, Irene [University Hospital Innsbruck, Department of Nuclear Medicine, Innsbruck (Austria)