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Sample records for lowering trial ideal

  1. Lessons learned from IDeAl - 33 recommendations from the IDeAl-net about design and analysis of small population clinical trials.

    Science.gov (United States)

    Hilgers, Ralf-Dieter; Bogdan, Malgorzata; Burman, Carl-Fredrik; Dette, Holger; Karlsson, Mats; König, Franz; Male, Christoph; Mentré, France; Molenberghs, Geert; Senn, Stephen

    2018-05-11

    IDeAl (Integrated designs and analysis of small population clinical trials) is an EU funded project developing new statistical design and analysis methodologies for clinical trials in small population groups. Here we provide an overview of IDeAl findings and give recommendations to applied researchers. The description of the findings is broken down by the nine scientific IDeAl work packages and summarizes results from the project's more than 60 publications to date in peer reviewed journals. In addition, we applied text mining to evaluate the publications and the IDeAl work packages' output in relation to the design and analysis terms derived from in the IRDiRC task force report on small population clinical trials. The results are summarized, describing the developments from an applied viewpoint. The main result presented here are 33 practical recommendations drawn from the work, giving researchers a comprehensive guidance to the improved methodology. In particular, the findings will help design and analyse efficient clinical trials in rare diseases with limited number of patients available. We developed a network representation relating the hot topics developed by the IRDiRC task force on small population clinical trials to IDeAl's work as well as relating important methodologies by IDeAl's definition necessary to consider in design and analysis of small-population clinical trials. These network representation establish a new perspective on design and analysis of small-population clinical trials. IDeAl has provided a huge number of options to refine the statistical methodology for small-population clinical trials from various perspectives. A total of 33 recommendations developed and related to the work packages help the researcher to design small population clinical trial. The route to improvements is displayed in IDeAl-network representing important statistical methodological skills necessary to design and analysis of small-population clinical trials. The methods

  2. Plasma triglycerides and cardiovascular events in the Treating to New Targets and Incremental Decrease in End-Points through Aggressive Lipid Lowering trials of statins in patients with coronary artery disease

    DEFF Research Database (Denmark)

    Faergeman, Ole; Holme, Ingar; Fayyad, Rana

    2009-01-01

    We determined the ability of in-trial measurements of triglycerides (TGs) to predict new cardiovascular events (CVEs) using data from the Incremental Decrease in End Points through Aggressive Lipid Lowering (IDEAL) and Treating to New Targets (TNT) trials. The trials compared atorvastatin 80 mg...

  3. Episodic Future Thinking about the Ideal Self Induces Lower Discounting, Leading to a Decreased Tendency toward Cheating.

    Science.gov (United States)

    Wu, Wen-Hsiung; Cheng, Wen; Chiou, Wen-Bin

    2017-01-01

    Delay discounting refers to a pervasive tendency toward preferring smaller immediate gains over larger future gains. Recent empirical research has shown that episodic future thinking (EFT; i.e., projecting oneself into the future to pre-experience forthcoming events) can reduce the tendency toward discounting. A common tenet of psychological theories of crime is that delinquency results from focusing on short-term gains while failing to consider adequately the longer-term consequences of delinquent behavior. We investigated whether an EFT intervention involving the ideal self could induce lower discounting rates and, as a consequence, reduced delinquency. The results showed that, compared with control participants, participants engaging in EFT, that is, envisaging life events that would be experienced by their ideal selves, exhibited a lower discounting rate in a monetary choice task (Experiments 1 and 2), as well as a decreased tendency to make delinquent choices in imaginary scenarios (Experiment 1) and cheat in a matrix task (Experiment 2). The discounting tendency mediated the relationship between engaging in EFT pertaining to the ideal self and the tendency toward morally questionable behavior (Experiments 1 and 2). The findings of the two experiments indicate that engagement in EFT with a focus on the ideal self is sufficient to induce lower discounting rates, by promoting consideration of distant costs and thus increasing resistance to delinquent involvement and cheating (given the temptation of the immediate benefits that may accrue from such behavior). The current research constitutes an innovative approach to delinquency prevention and the promotion of morality.

  4. The Anglo-Scandinavian Cardiac Outcomes Trial lipid lowering arm: extended observations 2 years after trial closure

    DEFF Research Database (Denmark)

    Sever, Peter S; Poulter, Neil R; Dahlof, Bjorn

    2008-01-01

    Aims To determine the cardiovascular benefits in those originally assigned atorvastatin in the Anglo-Scandinavian Cardiac Outcomes Trial-2.2 years after closure of the lipid-lowering arm of the trial (ASCOT-LLA). Methods and results The Blood Pressure Lowering Arm of the ASCOT trial (ASCOT......-BPLA) compared two different antihypertensive treatment strategies on cardiovascular outcomes. ASCOT-LLA was a double-blind placebo-controlled trial of atorvastatin in those enrolled into ASCOT-BPLA with total cholesterol concentrations at baseline of ... enrolled in ASCOT-BPLA and 10 305 were further assigned either atorvastatin, 10 mg, or placebo. ASCOT-LLA was stopped prematurely after a median 3.3 years follow-up because of substantial cardiovascular benefits in those assigned atorvastatin. Trial physicians were invited to offer atorvastatin to all...

  5. Potential synergy between lipid-lowering and blood-pressure-lowering in the Anglo-Scandinavian Cardiac Outcomes Trial

    DEFF Research Database (Denmark)

    Sever, Peter; Dahlöf, Björn; Poulter, Neil

    2006-01-01

    A prespecified objective of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) was to assess whether any synergistic effects were apparent between the lipid-lowering and blood-pressure-lowering regimens in preventing cardiovascular events....

  6. From the ideal market to the ideal clinic: constructing a normative standard of fairness for human subjects research.

    Science.gov (United States)

    Phillips, Trisha

    2011-02-01

    Preventing exploitation in human subjects research requires a benchmark of fairness against which to judge the distribution of the benefits and burdens of a trial. This paper proposes the ideal market and its fair market price as a criterion of fairness. The ideal market approach is not new to discussions about exploitation, so this paper reviews Wertheimer's inchoate presentation of the ideal market as a principle of fairness, attempt of Emanuel and colleagues to apply the ideal market to human subjects research, and Ballantyne's criticisms of both the ideal market and the resulting benchmark of fairness. It argues that the criticism of this particular benchmark is on point, but the rejection of the ideal market is mistaken. After presenting a complete account of the ideal market, this paper proposes a new method for applying the ideal market to human subjects research and illustrates the proposal by considering a sample case.

  7. [Lower Uterine Segment Trial: A pragmatic open multicenter randomized trial].

    Science.gov (United States)

    Rozenberg, P; Deruelle, P; Sénat, M-V; Desbrière, R; Winer, N; Simon, E; Ville, Y; Kayem, G; Boutron, I

    2018-04-01

    The data from literature show that trial of labor and elective repeat cesarean delivery after a prior cesarean delivery both present significant risks and benefits, and these risks and benefits differ for the woman and her fetus. The benefits to the woman can be at the expense of her fetus and vice-versa. This uncertainty is compounded by the scarcity of high-level evidence that preclude accurate quantification of the risks and benefits that could help provide a fair counseling about a trial of labor and elective repeat cesarean delivery. An interesting way of research is to evaluate the potential benefits of a decision rule associated to the ultrasound measurement of the lower uterine segment (LUS). Indeed, ultrasonography may be helpful in determining a specific risk for a given patient by measuring the thickness of the LUS, i,e, the thickness of the cesarean delivery scar area. Although only small and often methodologically biased data have been published, they look promising as their results are concordant: ultrasonographic measurements of the LUS thickness is highly correlated with the intraoperative findings at cesarean delivery. Furthermore, the thinner the LUS becomes on ultrasound, the higher the likelihood of a defect in the LUS. Finally, ultrasound assessment of LUS has an excellent negative predictive value for the risk of uterine defect. Therefore, this exam associated with a rule of decision could help to reduce the rate of elective repeat cesarean delivery and especially to reduce the fetal and maternal mortality and morbidity related to trial of labor after a prior cesarean delivery. This is a pragmatic open multicenter randomized trial with two parallel arms. Randomization will be centralized and computerized. Since blindness is impossible, an adjudication committee will evaluate the components of the primary composite outcome in order to avoid evaluation bias. An interim analysis will be planned mid-strength of the trial. Ultrasound will be

  8. Masculinity Ideals in a Contemporary Danish Context

    DEFF Research Database (Denmark)

    Bloksgaard, Lotte; Christensen, Ann-Dorte; Jensen, Sune Qvotrup

    2015-01-01

    discourses of gender. The article is based on a mixed methods design, consisting of: (1) a quantitative survey among lower-educated men in two male-dominated occupations, and (2) a qualitative, explorative analysis of data from five focus group interviews with both lower- and higher-educated men. The two...... occupations in the survey constitute a critical case, based on the argument that if traditional masculinity ideals are rejected here—among lower-educated men, who are likely to be more supportive of traditional gender ideals than the more highly educated—then Danish men in general are likely to reject...... traditional masculinity ideals. Both the quantitative and qualitative analyses indicate that traditional patriarchal masculinity ideals are not the most legitimate among the men. They seem to subscribe to more gender equality friendly masculinities, although this picture is not clear-cut as we also see...

  9. Increased body satisfaction after exposure to thin ideal children's television in young girls showing thin ideal internalisation.

    Science.gov (United States)

    Anschutz, Doeschka J; Engels, Rutger C M E; Van Strien, Tatjana

    2012-01-01

    This study tested the direct effect of watching thin ideal children's television on body satisfaction in preadolescent girls (6-8 years old). A within-subject design was used in which girls (N = 51) were tested three times. They watched television clips in random order containing either (1) thin ideal animated characters or (2) animated characters with no thin ideal features or (3) 'real' human actors with no thin ideal features. After watching, their state body satisfaction was measured. Girls with higher levels of thin ideal internalisation showed higher body satisfaction after exposure to the thin ideal characters than after exposure to animated or real characters featuring no thin ideal features. No differences on body satisfaction between the exposure conditions were found in girls with lower levels of thin ideal internalisation. The results might suggest that young girls who internalised the thin ideal are inspired by thin ideal characters in children's media.

  10. Hepatitis C treatment among racial and ethnic groups in the IDEAL trial.

    Science.gov (United States)

    Muir, A J; Hu, K-Q; Gordon, S C; Koury, K; Boparai, N; Noviello, S; Albrecht, J K; Sulkowski, M S; McCone, J

    2011-04-01

    Previous studies of chronic hepatitis C virus (HCV) treatment have demonstrated variations in response among racial and ethnic groups including poorer efficacy rates among African American and Hispanic patients. The individualized dosing efficacy vs flat dosing to assess optimaL pegylated interferon therapy (IDEAL) trial enrolled 3070 patients from 118 United States centres to compare treatment with peginterferon (PEG-IFN) alfa-2a and ribavirin (RBV) and two doses of PEG-IFN alfa-2b and RBV. This analysis examines treatment response among the major racial and ethnic groups in the trial. Overall, sustained virologic response (SVR) rates were 44% for white, 22% for African American, 38% for Hispanic and 59% for Asian American patients. For patients with undetectable HCV RNA at treatment week 4, the positive predictive value of SVR was 86% for white, 92% for African American, 83% for Hispanic and 89% for Asian American patients. The positive predictive values of SVR in those with undetectable HCV RNA at treatment week 12 ranged from 72% to 81%. Multivariate regression analysis using baseline characteristics demonstrated that treatment regimen was not a predictor of SVR. Despite wide-ranging SVR rates among the different racial and ethnic groups, white and Hispanic patients had similar SVR rates. In all groups, treatment response was largely determined by antiviral activity in the first 12 weeks of treatment. Therefore, decisions regarding HCV treatment should consider the predictive value of the early on-treatment response, not just baseline characteristics, such as race and ethnicity. © 2010 Blackwell Publishing Ltd.

  11. Tranexamic Acid for Lower GI Hemorrhage: A Randomized Placebo-Controlled Clinical Trial.

    Science.gov (United States)

    Smith, Stephen R; Murray, David; Pockney, Peter G; Bendinelli, Cino; Draganic, Brian D; Carroll, Rosemary

    2018-01-01

    Lower GI hemorrhage is a common source of morbidity and mortality. Tranexamic acid is an antifibrinolytic that has been shown to reduce blood loss in a variety of clinical conditions. Information regarding the use of tranexamic acid in treating lower GI hemorrhage is lacking. The aim of this trial was to determine the clinical efficacy of tranexamic acid when used for lower GI hemorrhage. This was a prospective, double-blind, placebo-controlled, randomized clinical trial. The study was conducted at a tertiary referral university hospital in Australia. Consecutive patients aged >18 years with lower GI hemorrhage requiring hospital admission from November 2011 to January 2014 were screened for trial eligibility (N = 265). A total of 100 patients were recruited after exclusions and were randomly assigned 1:1 to either tranexamic acid or placebo. The primary outcome was blood loss as determined by reduction in hemoglobin levels. The secondary outcomes were transfusion rates, transfusion volume, intervention rates for bleeding, length of hospital stay, readmission, and complication rates. There was no difference between groups with respect to hemoglobin drop (11 g/L of tranexamic acid vs 13 g/L of placebo; p = 0.9445). There was no difference with respect to transfusion rates (14/49 tranexamic acid vs 16/47 placebo; p = 0.661), mean transfusion volume (1.27 vs 1.93 units; p = 0.355), intervention rates (7/49 vs 13/47; p = 0.134), length of hospital stay (4.67 vs 4.74 d; p = 0.934), readmission, or complication rates. No complications occurred as a direct result of tranexamic acid use. A larger multicenter trial may be required to determine whether there are more subtle advantages with tranexamic acid use in some of the secondary outcomes. Tranexamic acid does not appear to decrease blood loss or improve clinical outcomes in patients presenting with lower GI hemorrhage in the context of this trial. see Video Abstract at http://links.lww.com/DCR/A453.

  12. Clinical Trials of Blood Pressure Lowering and Antihypertensive Medication: is Cognitive Measurement State-Of-The-Art?

    Science.gov (United States)

    Elias, Merrill F; Torres, Rachael V; Davey, Adam

    2018-02-22

    Randomized controlled trials of blood pressure (BP) lowering and antihypertensive medication use on cognitive outcomes have often been disappointing, reporting mixed findings and small effect sizes. We evaluate the extent to which cognitive assessment protocols used in these trials approach state-of-the-art. Overall, we find that a primary focus on cognition and the systematic selection of cognitive outcomes across trials take a backseat to other trial goals. Twelve trials investigating change in cognitive functioning were examined and none met criteria for state-of-the-art assessment, including use of at least 4 tests indexing 2 cognitive domains. Four trials investigating incident dementia were also examined. Each trial used state-of-the-art diagnostic criteria to assess dementia, although follow-up periods were relatively short, with only 2 trials lasting for at least 3 years. Weaknesses in each trial may act to obscure or weaken the positive effects of BP lowering on cognitive functioning. Improving trial designs in terms of cognitive outcomes selected and length of follow-up periods employed could lead to more promising findings. We offer logical steps to achieve state-of-the-art assessment protocols, with examples, in hopes of improving future trials.

  13. Design and rationale of the Procalcitonin Antibiotic Consensus Trial (ProACT), a multicenter randomized trial of procalcitonin antibiotic guidance in lower respiratory tract infection.

    Science.gov (United States)

    Huang, David T; Angus, Derek C; Chang, Chung-Chou H; Doi, Yohei; Fine, Michael J; Kellum, John A; Peck-Palmer, Octavia M; Pike, Francis; Weissfeld, Lisa A; Yabes, Jonathan; Yealy, Donald M

    2017-08-29

    Overuse of antibiotics is a major public health problem, contributing to growing antibiotic resistance. Procalcitonin has been reported to be commonly elevated in bacterial, but not viral infection. Multiple European trials found procalcitonin-guided care reduced antibiotic use in lower respiratory tract infection, with no apparent harm. However, applicability to US practice is limited due to trial design features impractical in the US, between-country differences, and residual safety concerns. The Procalcitonin Antibiotic Consensus Trial (ProACT) is a multicenter randomized trial to determine the impact of a procalcitonin antibiotic prescribing guideline, implemented with basic reproducible strategies, in US patients with lower respiratory tract infection. We describe the trial methods using the Consolidated Standards of Reporting Trials (CONSORT) framework, and the rationale for key design decisions, including choice of eligibility criteria, choice of control arm, and approach to guideline implementation. ClinicalTrials.gov NCT02130986 . Registered May 1, 2014.

  14. Changing Masculinity Ideals in a Danish Context

    DEFF Research Database (Denmark)

    Bloksgaard, Lotte; Christensen, Ann-Dorte

    , indicating that Danish masculinity ideals may be under change. Also several Nordic studies emphasize that traditional masculinity ideals are challenged by new, more ‘modern’ masculinity ideals related to fatherhood, child care and gender equality. The first part of the paper develops an analytical model......The purpose of this paper is to localize and discuss different masculinity ideals in a Danish context, and how these are overlapping and competing. The paper is based primarily on results from five focus group interviews with higher and lower educated men, respectively (n=50). This qualitative...... analysis builds on a survey conducted in the project ‘MARS’, which analyses the relation between masculinity and work-related accidents in two male dominated occupations. The survey shows that traditional masculinity ideals (the MRNI scale, Levant 2007) only find very low support (10 %) among the workers...

  15. Sugammadex by ideal body weight versus 20% and 40% corrected weight in bariatric surgery - double-blind randomized clinical trial

    Directory of Open Access Journals (Sweden)

    Nádia Maria da Conceição Duarte

    Full Text Available Abstract Background and objectives: The weight parameters for use of sugammadex in morbidly obese patients still need to be defined. Methods: A prospective clinical trial was conducted with sixty participants with body mass index ≥ 40 kg.m-2 during bariatric surgery, randomized into three groups: ideal weight (IW, 20% corrected body weight (CW20 and 40% corrected body weight (CW40. All patients received total intravenous anesthesia. Rocuronium was administered at dose of 0.6 mg.kg-1 of Ideal weight for tracheal intubation, followed by infusion of 0.3-0.6 mg.kg-1.h-1. Train of four (TOF was used to monitor depth of blockade. After spontaneous recovery TOF-count 2 at the end of surgery, 2 mg.kg-1 of sugammadex was administered. Primary outcome was neuromuscular blockade reversal time to TOF ≥ 0.9. Secondary outcome was the occurrence of postoperative residual curarization in post-anesthesia recovery room, searching the patient's ability to pass from the surgical bed to the transport, adequacy of oxygenation, respiratory pattern, ability to swallow saliva and clarity of vision. Results: Groups were homogenous in gender, age, total body weight, ideal body weight, body mass index, type and time of surgery. The reversal times (s were (mean ± standard deviation 225.2 ± 81.2, 173.9 ± 86.8 and 174.1 ± 74.9 respectively, in the IW, CW20 and CW40 groups (p = 0.087. Conclusions: No differences were observed between groups with neuromuscular blockade reversal time and frequency of postoperative residual curarization. We concluded that ideal body weight can be used to calculate sugammadex dose to reverse moderate neuromuscular blockade in morbidly obese patients.

  16. Childlessness Intentions and Ideals in Europe

    Directory of Open Access Journals (Sweden)

    Miettinen, Anneli

    2014-12-01

    Full Text Available Using data from Eurobarometer Surveys 2001–2011 we examine trends and correlates of childlessness intentions and ideals across Europe over the past decade. We distinguish childlessness as a personal preference (personal ideal number of children is zero from intended childlessness (intention to have no children as these reflect somewhat different dimensions of childlessness as a conscious decision. We find that, on average, childlessness as a personal preference is relatively rare in Europe, although in some western European countries a sizeable proportion of young adults express a desire to have no children. Intentional childlessness is slightly more common than ideal childlessness is, since about 11% of currently childless young adults aged 18 to 40 years in Europe intend to have no children. We analyse factors related to childlessness intentions and ideals on the individual and country levels. A weaker individual socioeconomic position influences the intention to remain childless through various channels, such as unemployment or low socioeconomic status. Associations between individual’s social position and ideal childlessness are less clear. Results also indicate that macro-economic conditions do not have a direct impact on intentional childlessness, whereas a higher prevalence of traditional family values in a country is related to a lower likelihood of individuals considering childlessness to be their ideal family form.

  17. Garlic intake lowers fasting blood glucose: meta-analysis of randomized controlled trials.

    Science.gov (United States)

    Hou, Li-qiong; Liu, Yun-hui; Zhang, Yi-yi

    2015-01-01

    Garlic is a common spicy flavouring agent also used for certain therapeutic purposes. Garlic's effects on blood glucose have been the subject of many clinical and animal studies, however, studies reporting hypoglycemic effects of garlic in humans are conflicting. A comprehensive literature search was conducted to identify relevant trials of garlic or garlic extracts on markers of glycemic control [fasting blood glucose (FBG), postprandial glucose (PPG), glycosylated haemoglobin (HbA1c)]. A meta-analysis of the effect of garlic intake on human was done to assess garlic's effectiveness in lowering glucose levels. Two reviewers extracted data from each of the identified studies. Seven eligible randomized controlled trials with 513 subjects were identified. Pooled analyses showed that garlic intake results in a statistically significant lowering in FBG [SMD=-1.67; 95% CI (-2.80, -0.55), p=0.004]. Our pooled analyses did not include PPG control and HbA1c outcomes. Because only 1 study included in the meta-analysis reported PPG variables and only 2 studies reported HbA1c variables. In conclusion, the current meta-analysis showed that the administration of garlic resulted in a significant reduction in FBG concentrations. More trials are needed to investigate the effectiveness of garlic on HbA1c and PPG.

  18. Lower limits of spin detection efficiency for two-parameter two-qubit (TPTQ) states with non-ideal ferromagnetic detectors

    Science.gov (United States)

    Majd, Nayereh; Ghasemi, Zahra

    2016-10-01

    We have investigated a TPTQ state as an input state of a non-ideal ferromagnetic detectors. Minimal spin polarization required to demonstrate spin entanglement according to entanglement witness and CHSH inequality with respect to (w.r.t.) their two free parameters have been found, and we have numerically shown that the entanglement witness is less stringent than the direct tests of Bell's inequality in the form of CHSH in the entangled limits of its free parameters. In addition, the lower limits of spin detection efficiency fulfilling secure cryptographic key against eavesdropping have been derived. Finally, we have considered TPTQ state as an output of spin decoherence channel and the region of ballistic transmission time w.r.t. spin relaxation time and spin dephasing time has been found.

  19. Total cardiovascular disease burden: comparing intensive with moderate statin therapy insights from the IDEAL (Incremental Decrease in End Points Through Aggressive Lipid Lowering) trial

    DEFF Research Database (Denmark)

    Tikkanen, Matti J; Szarek, Michael; Fayyad, Rana

    2009-01-01

    , using the Wei, Lin, and Weissfeld method. BACKGROUND: Time-to-first-event analysis of data is frequently utilized to provide efficacy outcome information in coronary heart disease prevention trials. However, during the course of such long-term trials, a large number of events occur subsequent...

  20. Not All Ideals are Equal: Intrinsic and Extrinsic Ideals in Relationships.

    Science.gov (United States)

    Rodriguez, Lindsey M; Hadden, Benjamin W; Knee, C Raymond

    2015-03-01

    The ideal standards model suggests that greater consistency between ideal standards and actual perceptions of one's relationship predicts positive relationship evaluations; however, no research has evaluated whether this differs across types of ideals. A self-determination theory perspective was derived to test whether satisfaction of intrinsic ideals buffers the importance of extrinsic ideals. Participants (N=195) in committed relationships directly and indirectly reported the extent to which their partner met their ideal on two dimensions: intrinsic (e.g., warm, intimate) and extrinsic (e.g., attractive, successful). Relationship need fulfillment and relationship quality were also assessed. Hypotheses were largely supported, such that satisfaction of intrinsic ideals more strongly predicted relationship functioning, and satisfaction of intrinsic ideals buffered the relevance of extrinsic ideals for outcomes.

  1. Students’ Perception on Ideal Age of Marriage and Childbearing

    Directory of Open Access Journals (Sweden)

    Mohanambehai Subranmiam

    2015-12-01

    Full Text Available Background: Early-age marriage is still common in Indonesia, especially in the rural areas. There are many negative effects of the marriage; the young brides may get lower education, lower social status, minimum reproduction control, higher maternal mortality, higher domestic violence rate and others. Thus, this study is conducted to identify the students’ perception on the ideal age of marriage and childbearing. Methods: A cross-sectional descriptive study was conducted from June to September 2013 in Jatinangor using secondary data from Jatinangor Cohort Survey Team. The data comprised two hundred and twenty students from Jatinangor Senior High School and PGRI Vocational School. A hundred and ten males and a hundred and ten females were chosen by random sampling. Questionnaires were given after the written informed consent was obtained from the students. Results: The results showed 74.55% of the students chose 19¬–24 years old as the ideal age of marriage for a woman and 68.64% students chose 25–30 years old as the ideal age of marriage for a man. Moreover, for childbearing, 25–30 years old was chosen to be the ideal age for both man and woman. The percentage of students agreed to this was 74.55% and 54.09% respectively. Conclusions: Majority of the students agreed on 19–24 years old and 25–30 years old as the ideal age of marriage for woman and man respectively. For childbearing, 25–30 years old was concluded as the ideal age for both genders.

  2. Procalcitonin guided antibiotic therapy and hospitalization in patients with lower respiratory tract infections: a prospective, multicenter, randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Henzen Christoph

    2007-07-01

    Full Text Available Abstract Background: Lower respiratory tract infections like acute bronchitis, exacerbated chronic obstructive pulmonary disease and community-acquired pneumonia are often unnecessarily treated with antibiotics, mainly because of physicians' difficulties to distinguish viral from bacterial cause and to estimate disease-severity. The goal of this trial is to compare medical outcomes, use of antibiotics and hospital resources in a strategy based on enforced evidence-based guidelines versus procalcitonin guided antibiotic therapy in patients with lower respiratory tract infections. Methods and design: We describe a prospective randomized controlled non-inferiority trial with an open intervention. We aim to randomize over a fixed recruitment period of 18 months a minimal number of 1002 patients from 6 hospitals in Switzerland. Patients must be >18 years of age with a lower respiratory tract infections Discussion: Use of and prolonged exposure to antibiotics in lower respiratory tract infections is high. The proposed trial investigates whether procalcitonin-guidance may safely reduce antibiotic consumption along with reductions in hospitalization costs and antibiotic resistance. It will additionally generate insights for improved prognostic assessment of patients with lower respiratory tract infections. Trial registration: ISRCTN95122877

  3. Neurocultural evidence that ideal affect match promotes giving.

    Science.gov (United States)

    Park, BoKyung; Blevins, Elizabeth; Knutson, Brian; Tsai, Jeanne L

    2017-07-01

    Why do people give to strangers? We propose that people trust and give more to those whose emotional expressions match how they ideally want to feel ("ideal affect match"). European Americans and Koreans played multiple trials of the Dictator Game with recipients who varied in emotional expression (excited, calm), race (White, Asian) and sex (male, female). Consistent with their culture's valued affect, European Americans trusted and gave more to excited than calm recipients, whereas Koreans trusted and gave more to calm than excited recipients. These findings held regardless of recipient race and sex. We then used fMRI to probe potential affective and mentalizing mechanisms. Increased activity in the nucleus accumbens (associated with reward anticipation) predicted giving, as did decreased activity in the right temporo-parietal junction (rTPJ; associated with reduced belief prediction error). Ideal affect match decreased rTPJ activity, suggesting that people may trust and give more to strangers whom they perceive to share their affective values. © The Author (2017). Published by Oxford University Press.

  4. Sex education and ideals

    NARCIS (Netherlands)

    de Ruyter, D.J.; Spiecker, B.

    2008-01-01

    This article argues that sex education should include sexual ideals. Sexual ideals are divided into sexual ideals in the strict sense and sexual ideals in the broad sense. It is argued that ideals that refer to the context that is deemed to be most ideal for the gratification of sexual ideals in the

  5. What is the Ideal Route of Administration of Tranexamic Acid in TKA? A Randomized Controlled Trial.

    Science.gov (United States)

    Lee, Sung Yup; Chong, Suri; Balasubramanian, Dhanasekaraprabu; Na, Young Gon; Kim, Tae Kyun

    2017-08-01

    TKA commonly involves substantial blood loss and tranexamic acid has been used to reduce blood loss after TKA. Numerous clinical trials have documented the efficacy and safety of intravenous (IV) or intraarticular (IA) use of tranexamic acid. Combined administration of tranexamic acid also has been suggested; however, there is no consensus regarding the ideal route of tranexamic acid administration. (1) To compare the efficacy of tranexamic acid in terms of total blood loss and the allogeneic transfusion rate among three routes of administration: IV alone, IA alone, and combined IV and IA. (2) To compare these regimens in terms of venous thromboembolism (VTE) and the frequency of wound complications. In total, 376 patients undergoing TKA between March 2014 and March 2015 were randomized to four groups by the route of tranexamic acid administration: IV only, IA only, low-dose combined (IV + IA injection of 1 g), and high-dose combined (IV + IA injection of 2 g). The calculated total blood loss, allogeneic transfusion rate, decrease in hemoglobin, the frequency of symptomatic deep vein thrombosis and pulmonary embolism, wound complications, and periprosthetic joint infection were compared among the groups. Total blood loss was calculated using estimated total body blood volume and hemoglobin loss. The decision regarding when to transfuse was determined based on preset criteria. The high- and low-dose combined groups and the IA-only group had lower total blood loss (564 ± 242 mL, 642 ± 242 mL, and 633 ± 205 mL, respectively) than the IV-only group (764 ± 217 mL; mean differences = 199 mL [95% CI, 116-283 mL], p tranexamic acid administration further reduces blood loss after TKA in comparison to IV use alone; no additional effect in further reducing blood loss was found in combination with IV tranexamic acid. Appropriately powered studies are needed to confirm the safety of this route of administration as the preferred route of administration in TKA. Level I

  6. Design of ideal cascades of gas centrifuges with variable separation factors

    International Nuclear Information System (INIS)

    Olander, D.R.

    1976-01-01

    A method of designing ideal cascades in which the separation factor varies with stage number is presented and applied to centrifuges as separating units. The centrifuge is characterized by a performance function, which gives the separative power, optimized with respect to all internal variables, as a function of cut and throughput. For centrifuges with certain types of performance functions, variable-α ideal cascades can provide a product at a lower cost than the conventional ideal cascade in which the separation factor is independent of stage number

  7. The Anglo-Scandinavian Cardiac Outcomes Trial: blood pressure-lowering limb: effects in patients with type II diabetes

    DEFF Research Database (Denmark)

    Ostergren, Jan; Poulter, Neil R; Sever, Peter S

    2008-01-01

    OBJECTIVE: To compare the effects of two antihypertensive treatment strategies for the prevention of coronary heart disease and other cardiovascular events in the large subpopulation (n=5137) with diabetes mellitus in the blood pressure-lowering arm of the Anglo-Scandinavian Cardiac Outcomes Trial...... nonsignificantly by 8% (hazard ratio 0.92, confidence interval 0.74-1.15). CONCLUSION: In the large diabetic subgroup in the blood pressure-lowering arm of the Anglo-Scandinavian Cardiac Outcomes Trial, the benefits of amlodipine-based treatment, compared with atenolol-based treatment, on the incidence of total...... with addition of thiazide as required (atenolol-based). Therapy was titrated to achieve a target blood pressure of less than 130/80 mmHg. RESULTS: The trial was terminated early due to significant benefits on mortality and stroke associated with the amlodipine-based regimen. In patients with diabetes mellitus...

  8. The magnetic properties of the hollow cylindrical ideal remanence magnet

    DEFF Research Database (Denmark)

    Bjørk, Rasmus

    2016-01-01

    We consider the magnetic properties of the hollow cylindrical ideal remanence magnet. This magnet is the cylindrical permanent magnet that generates a uniform field in the cylinder bore, using the least amount of magnetic energy to do so. The remanence distribution of this magnet is derived...... and the generated field is compared to that of a Halbach cylinder of equal dimensions. The ideal remanence magnet is shown in most cases to generate a significantly lower field than the equivalent Halbach cylinder, although the field is generated with higher efficiency. The most efficient Halbach cylinder is shown...... to generate a field exactly twice as large as the equivalent ideal remanence magnet....

  9. Lessons learned from a lipid lowering trial in adolescents with type 1 diabetes

    Directory of Open Access Journals (Sweden)

    Bishop Franziska K

    2012-07-01

    Full Text Available Abstract Herein, we describe recruitment efforts for a trial of lipid-lowering medications in adolescents with type 1 diabetes, age 12–21 years. Based on our experience, future studies will require multiple centers to enroll a sufficient number of participants for adequate data to direct dyslipidemia medication treatment guidelines for adolescents with type 1 diabetes.

  10. Randomized controlled trial of surface peroneal nerve stimulation for motor relearning in lower limb hemiparesis

    NARCIS (Netherlands)

    Sheffler, L.R.; Taylor, P.N.; Gunzler, D.D.; Buurke, Jaap; IJzerman, Maarten Joost; Chae, J.

    2013-01-01

    Objective: To compare the motor relearning effect of a surface peroneal nerve stimulator (PNS) versus usual care on lower limb motor impairment, activity limitation, and quality of life among chronic stroke survivors. Design: Single-blinded randomized controlled trial. Setting: Teaching hospital of

  11. Rough sets applied in sublattices and ideals of lattices

    Directory of Open Access Journals (Sweden)

    R. Ameri

    2015-12-01

    Full Text Available The purpose of this paper is the study of rough hyperlattice. In this regards we introduce rough sublattice and rough ideals of lattices. We will proceed by obtaining lower and upper approximations in these lattices.

  12. Weinhold'length in an isentropic Ideal and quasi-Ideal Gas

    OpenAIRE

    Santoro, Manuel

    2004-01-01

    In this paper we study thermodynamic length of an isentropic Ideal and quasi-Ideal Gas using Weinhold metric in a two-dimensional state space. We give explicit relation between length at constant entropy and work.

  13. Weinhold length in an isentropic ideal and quasi-ideal gas

    International Nuclear Information System (INIS)

    Santoro, Manuel

    2005-01-01

    In this paper, we study thermodynamic length of an isentropic ideal and quasi-ideal gas using Weinhold metric in a two-dimensional state space. We give explicit relation between length at constant entropy and work

  14. (Fuzzy) Ideals of BN-Algebras

    Science.gov (United States)

    Walendziak, Andrzej

    2015-01-01

    The notions of an ideal and a fuzzy ideal in BN-algebras are introduced. The properties and characterizations of them are investigated. The concepts of normal ideals and normal congruences of a BN-algebra are also studied, the properties of them are displayed, and a one-to-one correspondence between them is presented. Conditions for a fuzzy set to be a fuzzy ideal are given. The relationships between ideals and fuzzy ideals of a BN-algebra are established. The homomorphic properties of fuzzy ideals of a BN-algebra are provided. Finally, characterizations of Noetherian BN-algebras and Artinian BN-algebras via fuzzy ideals are obtained. PMID:26125050

  15. Effect of Increasing Doses of Saw Palmetto on Lower Urinary Tract Symptoms: A Randomized Trial

    Science.gov (United States)

    Barry, Michael J.; Meleth, Sreelatha; Lee, Jeannette Y.; Kreder, Karl J.; Avins, Andrew L.; Nickel, J. Curtis; Roehrborn, Claus G.; Crawford, E. David; Foster, Harris E.; Kaplan, Steven A.; McCullough, Andrew; Andriole, Gerald L.; Naslund, Michael J.; Williams, O. Dale; Kusek, John W.; Meyers, Catherine M.; Betz, Joseph M.; Cantor, Alan; McVary, Kevin T.

    2012-01-01

    Context Saw palmetto fruit extracts are widely used for treating lower urinary tract symptoms attributed to benign prostatic hyperplasia. However, recent clinical trials have questioned their efficacy, at least at standard doses (320 mg daily). Objective To determine the effect of a saw palmetto extract at up to three times the standard dose on lower urinary tract symptoms attributed to benign prostatic hyperplasia. Design Multicenter placebo-controlled randomized trial conducted from June, 2008 through October, 2010. Setting Eleven North American clinical sites. Participants Were men at least 45 years old, with a peak urinary flow rate ≥ 4 ml/sec, an AUA Symptom Index (AUASI) score ≥ 8 and ≤ 24, and no exclusions. Interventions One, two, and then three 320 mg daily doses of saw palmetto extract or placebo, with dose increases at 24 and 48 weeks. Main Outcome Measures Primary outcome was the difference in AUASI score from baseline to 72 weeks. Secondary outcomes were measures of urinary bother; nocturia; uroflow; postvoid residual; prostate-specific antigen; participants’ global assessments; and indices of sexual function, continence, sleep quality, and prostatitis symptoms. Results From baseline to 72 weeks, mean AUASI scores decreased from 14.4 to 12.2 points with saw palmetto and from 14.7 to 11.7 points with placebo. The group mean difference in AUASI score change from baseline to 72 weeks between the saw palmetto and placebo groups was 0.79 points favoring placebo (bound of the 95% confidence interval most favorable to saw palmetto was 1.77 points, one-sided P=0.91). Saw palmetto was no more effective than placebo for any secondary outcome. No attributable side effects were identified. Conclusions Increasing doses of a saw palmetto fruit extract did not reduce lower urinary tract symptoms more than placebo. (CAMUS study number NCT00603304 http://www.ClinicalTrials.gov) PMID:21954478

  16. Efficacy versus effectiveness trials : informing guidelines for asthma management

    NARCIS (Netherlands)

    Price, David; Hillyer, Elizabeth V.; van der Molen, Thys

    Purpose of review Randomized controlled trials, known as efficacy trials and long considered the gold standard for evidence-based asthma guidelines, are designed to test whether interventions have a benefit for selective patient populations under ideal conditions. The goal of pragmatic trials and

  17. Saturated ideal modes in advanced tokamak regimes in MAST

    International Nuclear Information System (INIS)

    Chapman, I.T.; Hua, M.-D.; Pinches, S.D.; Akers, R.J.; Field, A.R.; Hastie, R.J.; Michael, C.A.; Graves, J.P.

    2010-01-01

    MAST plasmas with a safety factor above unity and a profile with either weakly reversed shear or broad low-shear regions, regularly exhibit long-lived saturated ideal magnetohydrodynamic (MHD) instabilities. The toroidal rotation is flattened in the presence of such perturbations and the fast ion losses are enhanced. These ideal modes, distinguished as such by the notable lack of islands or signs of reconnection, are driven unstable as the safety factor approaches unity. This could be of significance for advanced scenarios, or hybrid scenarios which aim to keep the safety factor just above rational surfaces associated with deleterious resistive MHD instabilities, especially in spherical tokamaks which are more susceptible to such ideal internal modes. The role of rotation, fast ions and ion diamagnetic effects in determining the marginal mode stability is discussed, as well as the role of instabilities with higher toroidal mode numbers as the safety factor evolves to lower values.

  18. Congestive heart failure is associated with lipoprotein components in statin-treated patients with coronary heart disease Insights from the Incremental Decrease in End points Through Aggressive Lipid Lowering Trial (IDEAL)

    DEFF Research Database (Denmark)

    Holme, Ingar; Strandberg, Timo E; Faergeman, Ole

    2009-01-01

    BACKGROUND: Very few, if any, studies have assessed the ability of apolipoproteins to predict new-onset of congestive heart failure (HF) in statin-treated patients with coronary heart disease (CHD). AIMS: To employ the Incremental Decrease in End points Through Aggressive Lipid Lowering Trial...... with the occurrence of new-onset HF. Variables related to low-density lipoprotein cholesterol (LDL-C) carried less predictive information than those related to high-density lipoprotein cholesterol (HDL-C), and apoA-1 was the single variable most strongly associated with HF. LDL-C was less predictive than both non......-HDL-C (total cholesterol minus HDL-C) and apoB. The ratio of apoB to apoA-1 was most strongly related to HF after adjustment for potential confounders, among which diabetes had a stronger correlation with HF than did hypertension. ApoB/apoA-1 carried approximately 2.2 times more of the statistical information...

  19. Short-Term Effect of Laser Acupuncture on Lower Back Pain: A Randomized, Placebo-Controlled, Double-Blind Trial

    Directory of Open Access Journals (Sweden)

    Jae-Young Shin

    2015-01-01

    Full Text Available Purpose. This trial was performed to investigate the efficacy of laser acupuncture for the alleviation of lower back pain. Methods. This was a randomized, placebo-controlled, double-blind trial. Fifty-six participants were randomly assigned to either the laser acupuncture group (n=28 or the sham laser acupuncture group (n=28. Participants in both groups received three treatment sessions over the course of one week. Thirteen acupuncture points were selected. The visual analogue scale for pain, pressure pain threshold, Patient Global Impression of Change, and Euro-Quality-of-Life Five Dimensions questionnaire (Korean version were used to evaluate the effect of laser acupuncture treatment on lower back pain. Results. There were no significant differences in any outcome between the two groups, although the participants in both groups showed a significant improvement in each assessed parameter relative to the baseline values. Conclusion. Although there was no significant difference in outcomes between the two groups, the results suggest that laser acupuncture can provide effective pain alleviation and can be considered an option for relief from lower back pain. Further studies using long-term intervention, a larger sample size, and rigorous methodology are required to clarify the effect of laser acupuncture on lower back pain.

  20. Ideals in algebras of unbounded operators

    International Nuclear Information System (INIS)

    Timmermann, W.

    1977-01-01

    The paper presents a continuation of investigations on ideals in algebras of unbounded operators. A general procedure is given to get ideals in L + (D) starting with ideals in B(H). A definition of the two types of ideals is given: one contains only bounded operators, the other involves both bounded and unbounded operators. Some algebraic properties of ideals Ssub(phi)(D) derived from the well-known symmetrically normed ideals Ssub(phi) are investigated. Topologies in such ideals are introduced, and some results connected with topological properties of these ideals are given

  1. Improved DEA Cross Efficiency Evaluation Method Based on Ideal and Anti-Ideal Points

    Directory of Open Access Journals (Sweden)

    Qiang Hou

    2018-01-01

    Full Text Available A new model is introduced in the process of evaluating efficiency value of decision making units (DMUs through data envelopment analysis (DEA method. Two virtual DMUs called ideal point DMU and anti-ideal point DMU are combined to form a comprehensive model based on the DEA method. The ideal point DMU is taking self-assessment system according to efficiency concept. The anti-ideal point DMU is taking other-assessment system according to fairness concept. The two distinctive ideal point models are introduced to the DEA method and combined through using variance ration. From the new model, a reasonable result can be obtained. Numerical examples are provided to illustrate the new constructed model and certify the rationality of the constructed model through relevant analysis with the traditional DEA model.

  2. Ideal relaxation of the Hopf fibration

    Science.gov (United States)

    Smiet, Christopher Berg; Candelaresi, Simon; Bouwmeester, Dirk

    2017-07-01

    Ideal magnetohydrodynamics relaxation is the topology-conserving reconfiguration of a magnetic field into a lower energy state where the net force is zero. This is achieved by modeling the plasma as perfectly conducting viscous fluid. It is an important tool for investigating plasma equilibria and is often used to study the magnetic configurations in fusion devices and astrophysical plasmas. We study the equilibrium reached by a localized magnetic field through the topology conserving relaxation of a magnetic field based on the Hopf fibration in which magnetic field lines are closed circles that are all linked with one another. Magnetic fields with this topology have recently been shown to occur in non-ideal numerical simulations. Our results show that any localized field can only attain equilibrium if there is a finite external pressure, and that for such a field a Taylor state is unattainable. We find an equilibrium plasma configuration that is characterized by a lowered pressure in a toroidal region, with field lines lying on surfaces of constant pressure. Therefore, the field is in a Grad-Shafranov equilibrium. Localized helical magnetic fields are found when plasma is ejected from astrophysical bodies and subsequently relaxes against the background plasma, as well as on earth in plasmoids generated by, e.g., a Marshall gun. This work shows under which conditions an equilibrium can be reached and identifies a toroidal depression as the characteristic feature of such a configuration.

  3. Mathematics and geometry towards ideality in «Domus»’s ideal houses

    Directory of Open Access Journals (Sweden)

    Simona Chiodo

    2018-01-01

    Full Text Available Between 1942 and 1943 the editor of the journal «Domus» invited the most important Italian architects to design their ideal houses: fifteen projects designed by seventeen architects were published. They are most instructive to try to understand, firstly, what the philosophical notion of ideal means and, secondly, why mathematical and geometric tools are extensively used to work on ideality, namely, to design ideal houses. The first part of the article focuses on the philosophical foundations of ideality and, after an overview of the fifteen projects, on the use of the golden ratio in two particularly meaningful cases. The second part of the article focuses on the cases in which there is a hidden use of the golden ratio, on the use of the modulus and on the use of the number 2.

  4. Medical ethics and more: ideal theories, non-ideal theories and conscientious objection.

    Science.gov (United States)

    Luna, Florencia

    2015-01-01

    Doing 'good medical ethics' requires acknowledgment that it is often practised in non-ideal circumstances! In this article I present the distinction between ideal theory (IT) and non-ideal theory (NIT). I show how IT may not be the best solution to tackle problems in non-ideal contexts. I sketch a NIT framework as a useful tool for bioethics and medical ethics and explain how NITs can contribute to policy design in non-ideal circumstances. Different NITs can coexist and be evaluated vis-à-vis the IT. Additionally, I address what an individual doctor ought to do in this non-ideal context with the view that knowledge of NITs can facilitate the decision-making process. NITs help conceptualise problems faced in the context of non-compliance and scarcity in a better and more realistic way. Deciding which policy is optimal in such contexts may influence physicians' decisions regarding their patients. Thus, this analysis-usually identified only with policy making-may also be relevant to medical ethics. Finally, I recognise that this is merely a first step in an unexplored but fundamental theoretical area and that more work needs to be done. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  5. Monomial ideals, computations and applications

    CERN Document Server

    Gimenez, Philippe; Sáenz-de-Cabezón, Eduardo

    2013-01-01

    This work covers three important aspects of monomials ideals in the three chapters "Stanley decompositions" by Jürgen Herzog, "Edge ideals" by Adam Van Tuyl and "Local cohomology" by Josep Álvarez Montaner. The chapters, written by top experts, include computer tutorials that emphasize the computational aspects of the respective areas. Monomial ideals and algebras are, in a sense, among the simplest structures in commutative algebra and the main objects of combinatorial commutative algebra. Also, they are of major importance for at least three reasons. Firstly, Gröbner basis theory allows us to treat certain problems on general polynomial ideals by means of monomial ideals. Secondly, the combinatorial structure of monomial ideals connects them to other combinatorial structures and allows us to solve problems on both sides of this correspondence using the techniques of each of the respective areas. And thirdly, the combinatorial nature of monomial ideals also makes them particularly well suited to the devel...

  6. Second Order Ideal-Ward Continuity

    Directory of Open Access Journals (Sweden)

    Bipan Hazarika

    2014-01-01

    Full Text Available The main aim of the paper is to introduce a concept of second order ideal-ward continuity in the sense that a function f is second order ideal-ward continuous if I-limn→∞Δ2f(xn=0 whenever I-limn→∞Δ2xn=0 and a concept of second order ideal-ward compactness in the sense that a subset E of R is second order ideal-ward compact if any sequence x=(xn of points in E has a subsequence z=(zk=(xnk of the sequence x such that I-limk→∞Δ2zk=0 where Δ2zk=zk+2-2zk+1+zk. We investigate the impact of changing the definition of convergence of sequences on the structure of ideal-ward continuity in the sense of second order ideal-ward continuity and compactness of sets in the sense of second order ideal-ward compactness and prove related theorems.

  7. Ideals and anti-ideals students of the basic and senior school

    Directory of Open Access Journals (Sweden)

    Vladimir S. Sobkin

    2017-09-01

    Full Text Available The paper is devoted to the study of representations of the ideals and anti-ideals in secondary and high schools students. The study is important due to connection with the peculiarities of modern adolescent socialization in the context of contemporary social cultural realities. Shaping the world view in students is significantly influenced by the choice of values and the social role model. In this regard, the aim of this study was to examine gender and age dynamics of different groups of personalities related to the politics and spiritual culture in the structure of ideals and anti-idials in modern adolescents. Aggravation of the internal and external political situation, politically-oriented media content and society as a whole, the introduction of information technologies in various spheres of life, the «western» background of cultural values and information environment, the shift of sex-role identification has a significant influence on gender-specific and age-specific dynamics and significance of different groups of personalities in the structure of ideals and anti-idials in modern adolescents are based on the data of content analysis and a questionnaire survey of 2,273 students, grades 5-11. The features of the structure of ideals and anti-idials of boys and girls, which are formed under the influence of gender identification are characterized. The analysis of the students’ groups of ideals and anti-idials is held depending on their belonging to the Russian and foreign cultures. The students’ representations of the ideals and anti-idials are of a mixed structure, dominated by the personalities of the real people in comparison with the images (characters of works of literature, cinema, cartoons. The sphere of political culture and ideology (politicians, historical figures that presents male personalities is significant for boys. For girls, besides politics, the literary field (writers and movie actors is more important, where the

  8. Sugammadex by ideal body weight versus 20% and 40% corrected weight in bariatric surgery – double-blind randomized clinical trial

    Directory of Open Access Journals (Sweden)

    Nádia Maria da Conceição Duarte

    2018-05-01

    Full Text Available Background and objectives: The weight parameters for use of sugammadex in morbidly obese patients still need to be defined. Methods: A prospective clinical trial was conducted with sixty participants with body mass index ≥ 40 kg.m−2 during bariatric surgery, randomized into three groups: ideal weight (IW, 20% corrected body weight (CW20 and 40% corrected body weight (CW40. All patients received total intravenous anesthesia. Rocuronium was administered at dose of 0.6 mg.kg−1 of Ideal weight for tracheal intubation, followed by infusion of 0.3–0.6 mg.kg−1.h−1. Train of four (TOF was used to monitor depth of blockade. After spontaneous recovery TOF-count 2 at the end of surgery, 2 mg.kg−1 of sugammadex was administered. Primary outcome was neuromuscular blockade reversal time to TOF ≥ 0.9. Secondary outcome was the occurrence of postoperative residual curarization in post-anesthesia recovery room, searching the patient's ability to pass from the surgical bed to the transport, adequacy of oxygenation, respiratory pattern, ability to swallow saliva and clarity of vision. Results: Groups were homogenous in gender, age, total body weight, ideal body weight, body mass index, type and time of surgery. The reversal times (s were (mean ± standard deviation 225.2 ± 81.2, 173.9 ± 86.8 and 174.1 ± 74.9 respectively, in the IW, CW20 and CW40 groups (p = 0.087. Conclusions: No differences were observed between groups with neuromuscular blockade reversal time and frequency of postoperative residual curarization. We concluded that ideal body weight can be used to calculate sugammadex dose to reverse moderate neuromuscular blockade in morbidly obese patients. Resumo: Justificativa e objetivos: Os parâmetros de peso para o uso de sugamadex em pacientes com obesidade mórbida ainda precisam ser definidos. Métodos: Um ensaio clínico prospectivo foi realizado com sessenta participantes com índice de massa corporal ≥ 40

  9. Beware of ideals in education

    NARCIS (Netherlands)

    Heyting, G.F.

    2004-01-01

    In reaction to Doret De Ruyter's recent defence of the importance of ideals in education, I advocate cautiousness in three respects. First, I explain the importance of distinguishing ideals more sharply from goals by demonstrating the problems of considering ideals even approximately realisable.

  10. Intensive versus Guideline Blood Pressure and Lipid Lowering in Patients with Previous Stroke: Main Results from the Pilot 'Prevention of Decline in Cognition after Stroke Trial' (PODCAST Randomised Controlled Trial.

    Directory of Open Access Journals (Sweden)

    Philip M Bath

    Full Text Available Stroke is associated with the development of cognitive impairment and dementia. We assessed the effect of intensive blood pressure (BP and/or lipid lowering on cognitive outcomes in patients with recent stroke in a pilot trial.In a multicentre, partial-factorial trial, patients with recent stroke, absence of dementia, and systolic BP (SBP 125-170 mmHg were assigned randomly to at least 6 months of intensive (target SBP <125 mmHg or guideline (target SBP <140 mmHg BP lowering. The subset of patients with ischaemic stroke and total cholesterol 3.0-8.0 mmol/l were also assigned randomly to intensive (target LDL-cholesterol <1.3 mmol/l or guideline (target LDL-c <3.0 mmol/l lipid lowering. The primary outcome was the Addenbrooke's Cognitive Examination-Revised (ACE-R.We enrolled 83 patients, mean age 74.0 (6.8 years, and median 4.5 months after stroke. The median follow-up was 24 months (range 1-48. Mean BP was significantly reduced with intensive compared to guideline treatment (difference -10·6/-5·5 mmHg; p<0·01, as was total/LDL-cholesterol with intensive lipid lowering compared to guideline (difference -0·54/-0·44 mmol/l; p<0·01. The ACE-R score during treatment did not differ for either treatment comparison; mean difference for BP lowering -3.6 (95% CI -9.7 to 2.4, and lipid lowering 4.4 (95% CI -2.1 to 10.9. However, intensive lipid lowering therapy was significantly associated with improved scores for ACE-R at 6 months, trail making A, modified Rankin Scale and Euro-Qol Visual Analogue Scale. There was no difference in rates of dementia or serious adverse events for either comparison.In patients with recent stroke and normal cognition, intensive BP and lipid lowering were feasible and safe, but did not alter cognition over two years. The association between intensive lipid lowering and improved scores for some secondary outcomes suggests further trials are warranted.ISRCTN ISRCTN85562386.

  11. Design of the Revascularization With Open Bypass vs Angioplasty and Stenting of the Lower Extremity Trial (ROBUST): a randomized clinical trial.

    Science.gov (United States)

    Malas, Mahmoud B; Qazi, Umair; Glebova, Natalia; Arhuidese, Isibor; Reifsnyder, Thomas; Black, James; Perler, Bruce A; Freischlag, Julie A

    2014-12-01

    To our knowledge, there is no level 1 evidence comparing open bypass with angioplasty and stenting in TransAtlantic Inter-Society Consensus (TASC II) B and C superficial femoral artery lesions. The Revascularization With Open Bypass vs Angioplasty and Stenting of the Lower Extremity Trial (ROBUST) is the first prospective randomized clinical trial comparing both treatments. To report the design of the ROBUST trial. The primary aim of the trial is to compare (1) the patency rate (primary, primary assisted, and secondary patency at 6 and 12 months), (2) improvement of quality of life, (3) clinical improvement (at least 1 Rutherford category), and (4) wound healing and limb salvage in patients presenting with critical limb ischemia; secondary aims include (1) cost-effectiveness by factoring procedure and hospital admission costs including rehabilitation, readmission, and reintervention costs, (2) amputation-free survival, (3) reintervention rate, and (4) 30-day operative mortality, morbidity, and wound and access complications. ROBUST is a prospective randomized clinical trial with the aim to enroll 320 patients with intermittent claudication that does not respond to medical management and patients with critical limb ischemia. The maximum level of medical therapy will be administered using antiplatelet agents and statins, as well as measures to control hypertension and diabetes mellitus. Patients with TASC II B or C lesions are prospectively randomized to receive either femoropopliteal bypass or percutaneous transluminal angioplasty and stenting; patients with TASC II A and D lesions are not randomized and receive percutaneous transluminal angioplasty and stenting or femoropopliteal bypass, respectively. All patients will be evaluated at 1, 6, and 12 months postoperatively with physical examination, ankle brachial index, duplex, and a quality-of-life questionnaire. The trial is actively enrolling participants. At the time of writing, 29 patients have been enrolled

  12. The influence of family context on life, educational and occupational ideal among middle school students in China.

    Science.gov (United States)

    Yao, Benxian; Zhang, Ling; Zhen, Rui; Zhou, Xiao

    2016-06-01

    This study examined the relationship between family context of middle school students on their educational and occupational ideals. Middle school students (N = 2000) responded to questions assessing family location, family structure, parental educational level and family economic status, as well as to the Middle School Students' Ideals Questionnaire. Multivariate analysis of variance indicated that life, educational and occupational ideals of female students and students in lower grades were higher than that of male students and students in higher grades. Regression analysis indicated that paternal education level have a positive association with educational and occupational ideals, but not life ideals, and family economic status have a positive relation to life ideals, but not educational and occupational ideals. Moreover, the interaction between family economic status and family location has a negative association with students' life, educational and occupational ideals. These results suggest that different factors predicted different ideals of adolescents, and that family economic status had a negative moderating effect on the relationship between family location and ideals of students. © 2015 International Union of Psychological Science.

  13. Decomposition of fuzzy continuity and fuzzy ideal continuity via fuzzy idealization

    International Nuclear Information System (INIS)

    Zahran, A.M.; Abbas, S.E.; Abd El-baki, S.A.; Saber, Y.M.

    2009-01-01

    Recently, El-Naschie has shown that the notion of fuzzy topology may be relevant to quantum paretical physics in connection with string theory and E-infinity space time theory. In this paper, we study the concepts of r-fuzzy semi-I-open, r-fuzzy pre-I-open, r-fuzzy α-I-open and r-fuzzy β-I-open sets, which is properly placed between r-fuzzy openness and r-fuzzy α-I-openness (r-fuzzy pre-I-openness) sets regardless the fuzzy ideal topological space in Sostak sense. Moreover, we give a decomposition of fuzzy continuity, fuzzy ideal continuity and fuzzy ideal α-continuity, and obtain several characterization and some properties of these functions. Also, we investigate their relationship with other types of function.

  14. Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial.

    Directory of Open Access Journals (Sweden)

    A David Smith

    2010-09-01

    Full Text Available An increased rate of brain atrophy is often observed in older subjects, in particular those who suffer from cognitive decline. Homocysteine is a risk factor for brain atrophy, cognitive impairment and dementia. Plasma concentrations of homocysteine can be lowered by dietary administration of B vitamins.To determine whether supplementation with B vitamins that lower levels of plasma total homocysteine can slow the rate of brain atrophy in subjects with mild cognitive impairment in a randomised controlled trial (VITACOG, ISRCTN 94410159.Single-center, randomized, double-blind controlled trial of high-dose folic acid, vitamins B(6 and B(12 in 271 individuals (of 646 screened over 70 y old with mild cognitive impairment. A subset (187 volunteered to have cranial MRI scans at the start and finish of the study. Participants were randomly assigned to two groups of equal size, one treated with folic acid (0.8 mg/d, vitamin B(12 (0.5 mg/d and vitamin B(6 (20 mg/d, the other with placebo; treatment was for 24 months. The main outcome measure was the change in the rate of atrophy of the whole brain assessed by serial volumetric MRI scans.A total of 168 participants (85 in active treatment group; 83 receiving placebo completed the MRI section of the trial. The mean rate of brain atrophy per year was 0.76% [95% CI, 0.63-0.90] in the active treatment group and 1.08% [0.94-1.22] in the placebo group (P =  0.001. The treatment response was related to baseline homocysteine levels: the rate of atrophy in participants with homocysteine >13 µmol/L was 53% lower in the active treatment group (P =  0.001. A greater rate of atrophy was associated with a lower final cognitive test scores. There was no difference in serious adverse events according to treatment category.The accelerated rate of brain atrophy in elderly with mild cognitive impairment can be slowed by treatment with homocysteine-lowering B vitamins. Sixteen percent of those over 70 y old have mild

  15. Soft ideal topological space and mixed fuzzy soft ideal topological space

    Directory of Open Access Journals (Sweden)

    Manash Borah

    2019-01-01

    Full Text Available In this paper we introduce fuzzy soft ideal and mixed fuzzy soft ideal topological spaces and some properties of this space. Also we introduce fuzzy soft $I$-open set, fuzzy soft $\\alpha$-$I$-open set, fuzzy soft pre-$I$-open set, fuzzy soft semi-$I$-open set and fuzzy soft $\\beta$-$I$-open set and discuss some of their properties.

  16. Implicit Beliefs about Ideal Body Image Predict Body Image Dissatisfaction

    Directory of Open Access Journals (Sweden)

    Niclas eHeider

    2015-10-01

    Full Text Available We examined whether implicit measures of actual and ideal body image can be used to predict body dissatisfaction in young female adults. Participants completed two Implicit Relational Assessment Procedures (IRAPs to examine their implicit beliefs concerning actual (e.g., I am thin and desired ideal body image (e.g., I want to be thin. Body dissatisfaction was examined via self-report questionnaires and rating scales. As expected, differences in body dissatisfaction exerted a differential influence on the two IRAP scores. Specifically, the implicit belief that one is thin was lower in participants who exhibited a high degree of body dissatisfaction than in participants who exhibited a low degree of body dissatisfaction. In contrast, the implicit desire to be thin (i.e., thin ideal body image was stronger in participants who exhibited a high level of body dissatisfaction than in participants who were less dissatisfied with their body. Adding further weight to the idea that both IRAP measures captured different underlying constructs, we also observed that they correlated differently with body mass index, explicit body dissatisfaction, and explicit measures of actual and ideal body image. More generally, these findings underscore the advantage of using implicit measures that incorporate relational information relative to implicit measures that allow for an assessment of associative relations only.

  17. Quantifying disease activity in fatty-infiltrated skeletal muscle by IDEAL-CPMG in Duchenne muscular dystrophy.

    Science.gov (United States)

    Mankodi, Ami; Bishop, Courtney A; Auh, Sungyoung; Newbould, Rexford D; Fischbeck, Kenneth H; Janiczek, Robert L

    2016-10-01

    The purpose of this study was to explore the use of iterative decomposition of water and fat with echo asymmetry and least-squares estimation Carr-Purcell-Meiboom-Gill (IDEAL-CPMG) to simultaneously measure skeletal muscle apparent fat fraction and water T 2 (T 2,w ) in patients with Duchenne muscular dystrophy (DMD). In twenty healthy volunteer boys and thirteen subjects with DMD, thigh muscle apparent fat fraction was measured by Dixon and IDEAL-CPMG, with the IDEAL-CPMG also providing T 2,w as a measure of muscle inflammatory activity. A subset of subjects with DMD was followed up during a 48-week clinical study. The study was in compliance with the Patient Privacy Act and approved by the Institutional Review Board. Apparent fat fraction in the thigh muscles of subjects with DMD was significantly increased compared to healthy volunteer boys (p Muscle T 2,w measured by IDEAL-CPMG was independent of changes in apparent fat fraction. Muscle T 2,w was higher in the biceps femoris and vastus lateralis muscles of subjects with DMD (p muscles and six-minute walk distance (6MWD) in subjects with DMD. IDEAL-CPMG allowed independent and simultaneous quantification of skeletal muscle fatty degeneration and disease activity in DMD. IDEAL-CPMG apparent fat fraction and T 2,w may be useful as biomarkers in clinical trials of DMD as the technique disentangles two competing biological processes. Published by Elsevier B.V.

  18. Lacunary ideal convergence of multiple sequences

    Directory of Open Access Journals (Sweden)

    Bipan Hazarika

    2016-01-01

    Full Text Available An ideal I is a family of subsets of N×N which is closed under taking finite unions and subsets of its elements. In this article, the concept of lacunary ideal convergence of double sequences has been introduced. Also the relation between lacunary ideal convergent and lacunary Cauchy double sequences has been established. Furthermore, the notions of lacunary ideal limit point and lacunary ideal cluster points have been introduced and find the relation between these two notions. Finally, we have studied the properties such as solidity, monotonic.

  19. Non-ideal dust acoustic waves

    International Nuclear Information System (INIS)

    Konefka, F; Contreras, J P; Puerta, J; Castro, E; MartIn, P

    2008-01-01

    The dispersion relation for dust acoustic waves (DA waves) functionally depends on the state equation for the charged dust grains. The ideal gas equation is usually used for studying the effect of temperature on this dispersion relation. However, since the space occupied by the grains can be important in high-density plasmas, the non-ideal effects can be important in this case. This paper analyses the dispersion relation for DA waves, when more precise state equations are used as those described for Pade approximants. The correction to the usual wave equation has been determined and the break point in density, where the ideal gas-state equation has been found. The non-ideal effects are more important for short wavelength ones, and the limits where those effects become important are also studied. Since there are several experimental results for these kinds of waves, the importance of the non-ideal effects in these cases is analysed in detail.

  20. German Idealism Today

    DEFF Research Database (Denmark)

    This collection of essays provides an exemplary overwiew of the diversity and relevance of current scholarship on German Idealism. The importance of German Idealism for contemporary philosophy has recieved growing attention and acknowledgment throughout competing fields of contemporary philosophy...... scholarly debates beyond merely antiquarian perspectives. This renaissance has been a major factor of current efforts to bridge the gap between so-called "nalytic" and so-called "continental" philosophy. The volume provides a selection of readings that contributes to systematic treatments of philosophical...

  1. Randomized trials published in higher vs. lower impact journals differ in design, conduct, and analysis.

    Science.gov (United States)

    Bala, Malgorzata M; Akl, Elie A; Sun, Xin; Bassler, Dirk; Mertz, Dominik; Mejza, Filip; Vandvik, Per Olav; Malaga, German; Johnston, Bradley C; Dahm, Philipp; Alonso-Coello, Pablo; Diaz-Granados, Natalia; Srinathan, Sadeesh K; Hassouneh, Basil; Briel, Matthias; Busse, Jason W; You, John J; Walter, Stephen D; Altman, Douglas G; Guyatt, Gordon H

    2013-03-01

    To compare methodological characteristics of randomized controlled trials (RCTs) published in higher vs. lower impact Core Clinical Journals. We searched MEDLINE for RCTs published in 2007 in Core Clinical Journals. We randomly sampled 1,140 study reports in a 1:1 ratio in higher (five general medicine journals with the highest total citations in 2007) and lower impact journals. Four hundred sixty-nine RCTs proved eligible: 219 in higher and 250 in lower impact journals. RCTs in higher vs. lower impact journals had larger sample sizes (median, 285 vs. 39), were more likely to receive industry funding (53% vs. 28%), declare concealment of allocation (66% vs. 36%), declare blinding of health care providers (53% vs. 41%) and outcome adjudicators (72% vs. 54%), report a patient-important primary outcome (69% vs. 50%), report subgroup analyses (64% vs. 26%), prespecify subgroup hypotheses (42% vs. 20%), and report a test for interaction (54% vs. 27%); P journals were more likely to report methodological safeguards against bias and patient-important outcomes than those published in lower impact journals. However, sufficient limitations remain such that publication in a higher impact journal does not ensure low risk of bias. Copyright © 2013 Elsevier Inc. All rights reserved.

  2. Ideal MHD beta-limits of poloidally asymmetric equilibria

    Energy Technology Data Exchange (ETDEWEB)

    Todd, A.M.M.; Miller, A.E.; Grimm, R.C.; Okabayashi, M.; Dalhed, H.E. Jr.

    1981-05-01

    The ideal MHD stability of poloidally asymmetric equilibria, which are typical of a tokamak reactor design with a single-null poloidal divertor is examined. As with symmetric equilibria, stability to non-axisymmetric modes improves with increasing triangularity and ellipticity, and with lower edge safety factor. Pressure profiles optimized with respect to ballooning stability are obtained for an asymmetric shape, resulting in ..beta../sub critical/ approx. = 5.7%. The corresponding value for an equivalent symmetric shape is ..beta../sub critical/ approx. = 6.5%.

  3. Ideal MHD beta-limits of poloidally asymmetric equilibria

    International Nuclear Information System (INIS)

    Todd, A.M.M.; Miller, A.E.; Grimm, R.C.; Okabayashi, M.; Dalhed, H.E. Jr.

    1981-05-01

    The ideal MHD stability of poloidally asymmetric equilibria, which are typical of a tokamak reactor design with a single-null poloidal divertor is examined. As with symmetric equilibria, stability to non-axisymmetric modes improves with increasing triangularity and ellipticity, and with lower edge safety factor. Pressure profiles optimized with respect to ballooning stability are obtained for an asymmetric shape, resulting in β/sub critical/ approx. = 5.7%. The corresponding value for an equivalent symmetric shape is β/sub critical/ approx. = 6.5%

  4. Prevention of Decline in Cognition after Stroke Trial (PODCAST): a study protocol for a factorial randomised controlled trial of intensive versus guideline lowering of blood pressure and lipids

    Science.gov (United States)

    2013-01-01

    Background Stroke is a common cause of cognitive impairment and dementia. However, effective strategies for reducing the risk of post-stroke dementia remain undefined. Potential strategies include intensive lowering of blood pressure and/or lipids. Methods/Design Design: multi-centre prospective randomised open-label blinded-endpoint controlled partial-factorial phase IV trial in secondary and primary care. Participants: 100 participants from 30 UK Stroke Research Network sites who are post- ischemic stroke or intracerebral haemorrhage by three to seven months. Interventions - all patients (1:1): intensive versus guideline blood pressure lowering (target systolic cognitive decline and dementia in people with ischemic stroke; and does ‘intensive’ blood pressure lowering therapy reduce cognitive decline and dementia in patients with hemorrhagic stroke. Primary outcome: Addenbrooke’s Cognitive Examination-Revised. Secondary outcomes: feasibility of recruitment and retention of participants, tolerability and safety of the interventions, achieving and maintaining the blood pressure and lipid targets, maintaining differences in systolic blood pressure (> 10 mmHg) and low density lipoprotein-cholesterol (> 1 mmol/l) between the treatment groups, and performing clinic and telephone follow-up of cognition measures. Randomisation: using stratification, minimization and simple randomization. Blinding: participants receive open-label management. Cognition is assessed both unblinded (in clinic) and blinded (by telephone) to treatment. Adjudication of events (dementia, vascular, serious adverse events) is blinded to management. Discussion The PODCAST trial is ongoing with 78 patients recruited to date from 22 sites. Outcomes of cognitive impairment and dementia are accruing. Trial registration ISRCTN85562386 PMID:24266960

  5. Assessment of Implicit Self-Esteem in Older Adults: The Role of Actual and Ideal Self-Esteem in Negative Mood.

    Science.gov (United States)

    Demeyer, Ineke; Romero, Nuria; De Raedt, Rudi

    2018-04-01

    The interplay between actual and ideal self-esteem may be a key component in emotional disorders. Since automatic self-evaluations are not always consciously accessible, assessment through implicit measures is necessary. Given the lack of implicit self-esteem measures in late life, we aimed to identify a reliable measure and to clarify the role of actual and ideal self-esteem in mood and depressive symptoms in older adults. Forty-nine older adults completed two adapted Go/No go Association tasks measuring implicit actual and ideal self-esteem and measures of mood and depressive symptoms. The two Go/No go Association tasks showed satisfactory internal consistency. Moderation analyses revealed that lower actual self-esteem in older adults is related to higher levels of sad mood when ideal self-esteem is high. Moreover, lower actual self-esteem is related to more anxious mood. Given the role of self-esteem in emotional well-being, a reliable measure for older adults is crucial to improve age-appropriate diagnostics and treatment.

  6. Bose-Einstein condensation in the relativistic ideal Bose gas.

    Science.gov (United States)

    Grether, M; de Llano, M; Baker, George A

    2007-11-16

    The Bose-Einstein condensation (BEC) critical temperature in a relativistic ideal Bose gas of identical bosons, with and without the antibosons expected to be pair-produced abundantly at sufficiently hot temperatures, is exactly calculated for all boson number densities, all boson point rest masses, and all temperatures. The Helmholtz free energy at the critical BEC temperature is lower with antibosons, thus implying that omitting antibosons always leads to the computation of a metastable state.

  7. Bose-Einstein Condensation in the Relativistic Ideal Bose Gas

    International Nuclear Information System (INIS)

    Grether, M.; Llano, M. de; Baker, George A. Jr.

    2007-01-01

    The Bose-Einstein condensation (BEC) critical temperature in a relativistic ideal Bose gas of identical bosons, with and without the antibosons expected to be pair-produced abundantly at sufficiently hot temperatures, is exactly calculated for all boson number densities, all boson point rest masses, and all temperatures. The Helmholtz free energy at the critical BEC temperature is lower with antibosons, thus implying that omitting antibosons always leads to the computation of a metastable state

  8. Least median of squares and iteratively re-weighted least squares as robust linear regression methods for fluorimetric determination of α-lipoic acid in capsules in ideal and non-ideal cases of linearity.

    Science.gov (United States)

    Korany, Mohamed A; Gazy, Azza A; Khamis, Essam F; Ragab, Marwa A A; Kamal, Miranda F

    2018-03-26

    This study outlines two robust regression approaches, namely least median of squares (LMS) and iteratively re-weighted least squares (IRLS) to investigate their application in instrument analysis of nutraceuticals (that is, fluorescence quenching of merbromin reagent upon lipoic acid addition). These robust regression methods were used to calculate calibration data from the fluorescence quenching reaction (∆F and F-ratio) under ideal or non-ideal linearity conditions. For each condition, data were treated using three regression fittings: Ordinary Least Squares (OLS), LMS and IRLS. Assessment of linearity, limits of detection (LOD) and quantitation (LOQ), accuracy and precision were carefully studied for each condition. LMS and IRLS regression line fittings showed significant improvement in correlation coefficients and all regression parameters for both methods and both conditions. In the ideal linearity condition, the intercept and slope changed insignificantly, but a dramatic change was observed for the non-ideal condition and linearity intercept. Under both linearity conditions, LOD and LOQ values after the robust regression line fitting of data were lower than those obtained before data treatment. The results obtained after statistical treatment indicated that the linearity ranges for drug determination could be expanded to lower limits of quantitation by enhancing the regression equation parameters after data treatment. Analysis results for lipoic acid in capsules, using both fluorimetric methods, treated by parametric OLS and after treatment by robust LMS and IRLS were compared for both linearity conditions. Copyright © 2018 John Wiley & Sons, Ltd.

  9. Ideal MHD stability and performance of ITER steady-state scenarios with ITBs

    Science.gov (United States)

    Poli, F. M.; Kessel, C. E.; Chance, M. S.; Jardin, S. C.; Manickam, J.

    2012-06-01

    Non-inductive steady-state scenarios on ITER will need to operate with internal transport barriers (ITBs) in order to reach adequate fusion gain at typical currents of 9 MA. The large pressure gradients at the location of the internal barrier are conducive to the development of ideal MHD instabilities that may limit the plasma performance and may lead to plasma disruptions. Fully non-inductive scenario simulations with five combinations of heating and current drive sources are presented in this work, with plasma currents in the range 7-10 MA. For each configuration the linear, ideal MHD stability is analysed for variations of the Greenwald fraction and of the pressure peaking factor around the operating point, aiming at defining an operational space for stable, steady-state operations at optimized performance. It is shown that plasmas with lower hybrid heating and current drive maintain the minimum safety factor above 1.5, which is desirable in steady-state operations to avoid neoclassical tearing modes. Operating with moderate ITBs at 2/3 of the minor radius, these plasmas have a minimum safety factor above 2, are ideal MHD stable and reach Q ≳ 5 operating above the ideal no-wall limit.

  10. Two-step condensation of the ideal Bose gas in highly anisotropic traps

    NARCIS (Netherlands)

    van Druten, N.J.; Ketterle, W.

    1997-01-01

    The ideal Bose gas in a highly anisotropic harmonic potential is studied. It is found that Bose-Einstein condensation occurs in two distinct steps as the temperature is lowered. In the first step the specific heat shows a sharp feature, but the system still occupies many one-dimensional quantum

  11. Certain variants of multipermutohedron ideals

    Indian Academy of Sciences (India)

    quotient of an Alexander dual of a multipermutohedron ideal is the number of .... It is clearly indicated in [10] that combinatorially defined monomial ideals ...... of the 31st Southeastern International Conference on Combinatorics, Graph Theory.

  12. Effect of Uric Acid-Lowering Agents on Endothelial Function: A Randomized, Double-Blind, Placebo-Controlled Trial.

    Science.gov (United States)

    Borgi, Lea; McMullan, Ciaran; Wohlhueter, Ann; Curhan, Gary C; Fisher, Naomi D; Forman, John P

    2017-02-01

    Higher levels of serum uric acid are independently associated with endothelial dysfunction, a mechanism for incident hypertension. Overweight/obese individuals are more prone to endothelial dysfunction than their lean counterparts. However, the effect of lowering serum uric acid on endothelial dysfunction in these individuals has not been examined thoroughly. In this randomized, double-blind, placebo-controlled trial of nonhypertensive, overweight, or obese individuals with higher serum uric acid (body mass index ≥25 kg/m 2 and serum uric acid ≥5.0 mg/dL), we assigned subjects to probenecid (500-1000 mg/d), allopurinol (300-600 mg/d), or matching placebo. The primary outcome was endothelium-dependent vasodilation measured by brachial artery ultrasound at baseline and 8 weeks. By the end of the trial, 47, 49, and 53 participants had been allocated to receive probenecid, allopurinol, and placebo, respectively. Mean serum uric acid levels significantly decreased in the probenecid (from 6.1 to 3.5 mg/dL) and allopurinol groups (from 6.1 to 2.9 mg/dL) but not in the placebo group (6.1 to 5.6 mg/dL). None of the interventions produced any significant change in endothelium-dependent vasodilation (probenecid, 7.4±5.1% at baseline and 8.3±5.1% at 8 weeks; allopurinol, 7.6±6.0% at baseline and 6.2±4.8% at 8 weeks; and placebo, 6.5±3.8% at baseline and 7.1±4.9% at 8 weeks). In this randomized, double-blind, placebo-controlled trial, uric acid lowering did not affect endothelial function in overweight or obese nonhypertensive individuals. These data do not support the hypothesis that uric acid is causally related to endothelial dysfunction, a potential mechanism for development of hypertension. © 2016 American Heart Association, Inc.

  13. Strong Ideal Convergence in Probabilistic Metric Spaces

    Indian Academy of Sciences (India)

    In the present paper we introduce the concepts of strongly ideal convergent sequence and strong ideal Cauchy sequence in a probabilistic metric (PM) space endowed with the strong topology, and establish some basic facts. Next, we define the strong ideal limit points and the strong ideal cluster points of a sequence in this ...

  14. Socrates: Platonic Political Ideal

    Directory of Open Access Journals (Sweden)

    Christopher P. Long

    2012-08-01

    Full Text Available This essay articulates the differences and suggests the similarities between the practices of Socratic political speaking and those of Platonic political writing. The essay delineates Socratic speaking and Platonic writing as both erotically oriented toward ideals capable of transforming the lives of individuals and their relationships with one another. Besides it shows that in the Protagoras the practices of Socratic political speaking are concerned less with Protagoras than with the individual young man, Hippocrates. In the Phaedo, this ideal of a Socrates is amplified in such a way that Platonic writing itself emerges as capable of doing with readers what Socratic speaking did with those he encountered. Socrates is the Platonic political ideal. The result is a picture of the transformative political power of Socratic speaking and Platonic writing both.

  15. Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals12345

    Science.gov (United States)

    Clarke, Robert; Bennett, Derrick; Parish, Sarah; Lewington, Sarah; Skeaff, Murray; Eussen, Simone JPM; Lewerin, Catharina; Stott, David J; Armitage, Jane; Hankey, Graeme J; Lonn, Eva; Spence, J David; Galan, Pilar; de Groot, Lisette C; Halsey, Jim; Dangour, Alan D; Collins, Rory; Grodstein, Francine

    2014-01-01

    Background: Elevated plasma homocysteine is a risk factor for Alzheimer disease, but the relevance of homocysteine lowering to slow the rate of cognitive aging is uncertain. Objective: The aim was to assess the effects of treatment with B vitamins compared with placebo, when administered for several years, on composite domains of cognitive function, global cognitive function, and cognitive aging. Design: A meta-analysis was conducted by using data combined from 11 large trials in 22,000 participants. Domain-based z scores (for memory, speed, and executive function and a domain-composite score for global cognitive function) were available before and after treatment (mean duration: 2.3 y) in the 4 cognitive-domain trials (1340 individuals); Mini-Mental State Examination (MMSE)–type tests were available at the end of treatment (mean duration: 5 y) in the 7 global cognition trials (20,431 individuals). Results: The domain-composite and MMSE-type global cognitive function z scores both decreased with age (mean ± SE: −0.054 ± 0.004 and −0.036 ± 0.001/y, respectively). Allocation to B vitamins lowered homocysteine concentrations by 28% in the cognitive-domain trials but had no significant effects on the z score differences from baseline for individual domains or for global cognitive function (z score difference: 0.00; 95% CI: −0.05, 0.06). Likewise, allocation to B vitamins lowered homocysteine by 26% in the global cognition trials but also had no significant effect on end-treatment MMSE-type global cognitive function (z score difference: −0.01; 95% CI: −0.03, 0.02). Overall, the effect of a 25% reduction in homocysteine equated to 0.02 y (95% CI: −0.10, 0.13 y) of cognitive aging per year and excluded reductions of >1 mo per year of treatment. Conclusion: Homocysteine lowering by using B vitamins had no significant effect on individual cognitive domains or global cognitive function or on cognitive aging. PMID:24965307

  16. Statistical mechanics of an ideal gas of non-Abelian anyons

    International Nuclear Information System (INIS)

    Mancarella, Francesco; Trombettoni, Andrea; Mussardo, Giuseppe

    2013-01-01

    We study the thermodynamical properties of an ideal gas of non-Abelian Chern–Simons particles and we compute the second virial coefficient, considering the effect of general soft-core boundary conditions for the two-body wavefunction at zero distance. The behaviour of the second virial coefficient is studied as a function of the Chern–Simons coupling, the isospin quantum number and the hard-core parameters. Expressions for the main thermodynamical quantities at the lower order of the virial expansion are also obtained: we find that at this order the relation between the internal energy and the pressure is the same found (exactly) for 2D Bose and Fermi ideal gases. A discussion of the comparison of obtained findings with available results in literature for systems of hard-core non-Abelian Chern–Simons particles is also supplied.

  17. Extremely strict ideals in Banach spaces

    Indian Academy of Sciences (India)

    Abstract. Motivated by the notion of an ideal introduced by Godefroy et al. (Stu- dia Math. 104 (1993) 13–59), in this article, we introduce and study the notion of an extremely strict ideal. For a Poulsen simplex K, we show that the space of affine contin- uous functions on K is an extremely strict ideal in the space of continuous ...

  18. The ideal tensile strength and deformation behavior of a tungsten single crystal

    International Nuclear Information System (INIS)

    Liu Yuelin; Zhou Hongbo; Zhang Ying; Jin Shuo; Lu Guanghong

    2009-01-01

    We employ first-principles total energy method based on the density functional theory with the generalized gradient approximation to investigate the ideal tensile strengths of a bcc tungsten (W) single crystal systemically. The ideal tensile strengths are shown to be 29.1, 49.2 and 37.6 GPa for bcc W in the [0 0 1], [1 1 0] and [1 1 1] directions, respectively. The [0 0 1] direction is shown to be the weakest direction due to the occurrence of structure transition at the lower strain and the [1 1 0] direction is strongest. The results can provide a useful reference for W as a PFM in the nuclear fusion Tokamak.

  19. Cycling Time Trial Performance 4 Hours After Glycogen-Lowering Exercise Is Similarly Enhanced by Recovery Nondairy Chocolate Beverages Versus Chocolate Milk.

    Science.gov (United States)

    Upshaw, Adam U; Wong, Tiffany S; Bandegan, Arash; Lemon, Peter W

    2016-02-01

    Postexercise chocolate milk ingestion has been shown to enhance both glycogen resynthesis and subsequent exercise performance. To assess whether nondairy chocolate beverage ingestion post-glycogen-lowering exercise can enhance 20-km cycling time trial performance 4 hr later, eight healthy trained male cyclists (21.8 ± 2.3y, VO2max = 61.2 ± 1.4 ml·kg-1·min-1; M ± SD) completed a series of intense cycling intervals designed to lower muscle glycogen (Jentjens & Jeukendrup, 2003) followed by 4 hr of recovery and a subsequent 20-km cycling time trial. During the first 2 hr of recovery, participants ingested chocolate dairy milk (DAIRYCHOC), chocolate soy beverage (SOYCHOC), chocolate hemp beverage (HEMPCHOC), low-fat dairy milk (MILK), or a low-energy artificially sweetened, flavored beverage (PLACEBO) at 30-min intervals in a double-blind, counterbalanced repeated-measures design. All drinks, except the PLACEBO (247 kJ) were isoenergetic (2,107 kJ), and all chocolate-flavored drinks provided 1-g CHO·kg body mass-1·h-1. Fluid intake across treatments was equalized (2,262 ± 148 ml) by ingesting appropriate quantities of water based on drink intake. The CHO:PRO ratio was 4:1, 1.5:1, 4:1, and 6:1 for DAIRYCHOC, MILK, SOYCHOC, and HEMPCHOC, respectively. One-way analysis of variance with repeated measures showed time trial performance (DAIRYCHOC = 34.58 ± 2.5 min, SOYCHOC = 34.83 ± 2.2 min, HEMPCHOC = 34.88 ± 1.1 min, MILK = 34.47 ± 1.7 min) was enhanced similarly vs PLACEBO (37.85 ± 2.1) for all treatments (p = .019) These data suggest that postexercise macronutrient and total energy intake are more important for same-day 20-km cycling time trial performance after glycogen-lowering exercise than protein type or protein-to-carbohydrate ratio.

  20. Elevated vacuum suspension preserves residual-limb skin health in people with lower-limb amputation: Randomized clinical trial.

    Science.gov (United States)

    Rink, Cameron; Wernke, Matthew M; Powell, Heather M; Gynawali, Surya; Schroeder, Ryan M; Kim, Jayne Y; Denune, Jeffrey A; Gordillo, Gayle M; Colvin, James M; Sen, Chandan K

    2016-01-01

    A growing number of clinical trials and case reports support qualitative claims that use of an elevated vacuum suspension (EVS) prosthesis improves residual-limb health on the basis of self-reported questionnaires, clinical outcomes scales, and wound closure studies. Here, we report first efforts to quantitatively assess residual-limb circulation in response to EVS. Residual-limb skin health and perfusion of people with lower-limb amputation (N = 10) were assessed during a randomized crossover study comparing EVS with nonelevated vacuum suspension (control) over a 32 wk period using noninvasive probes (transepidermal water loss, laser speckle imaging, transcutaneous oxygen measurement) and functional hyperspectral imaging approaches. Regardless of the suspension system, prosthesis donning decreased perfusion in the residual limb under resting conditions. After 16 wk of use, EVS improved residual-limb oxygenation during treadmill walking. Likewise, prosthesis-induced reactive hyperemia was attenuated with EVS following 16 wk of use. Skin barrier function was preserved with EVS but disrupted after control socket use. Taken together, outcomes suggest chronic EVS use improves perfusion and preserves skin barrier function in people with lower-limb amputation. ClinicalTrials.gov; "Evaluation of limb health associated with a prosthetic vacuum socket system": NCT01839123; https://clinicaltrials.gov/ct2/show/NCT01839123?term=NCT01839123&rank=1.

  1. On (m, n)-absorbing ideals of commutative rings

    Indian Academy of Sciences (India)

    with respect to various ring theoretic constructions and study (m, n)-absorbing ideals in several commutative rings. For example, in a Bézout ring or a Boolean ring, an ideal is an (m, n)-absorbing ideal if and only if it is an n-absorbing ideal, and in an almost. Dedekind domain every (m, n)-absorbing ideal is a product of at ...

  2. Value preserving quantum measurements: impossibility theorems and lower bounds for the distortion

    International Nuclear Information System (INIS)

    Ghirardi, G.C.; Trieste Univ.; Rimini, A.; Weber, T.

    1982-11-01

    Extending previous works on the subject, we consider the problem of the limitations to ideal quantum measurements arising from the presence of additive conservation laws. We derive impossibility theorems and lower bounds for the deviations from the ideal schemes, with particular reference to the distorting case. (author)

  3. Valutazione economica dello studio IDEAL

    Directory of Open Access Journals (Sweden)

    Enrica Menditto

    2007-10-01

    Full Text Available Introduction: the IDEAL (“High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction” study was carried out to compare intensive lowering of low-density lipoprotein (LDL-cholesterol using the highest recommended dose of atorvastatin 80 mg with simvastatin 40 mg. Aim: our aim was to investigate the economic consequence of high dose of atorvastatin vs usual-dose of simvastatin in reducing major coronary events in patients with a history of acute myocardial infarction (AMI. Methods: the analysis is based on clinical outcome data from the IDEAL study. We conducted a cost-effectiveness analysis, comparing high dose of atorvastatin (80 mg/die versus usual-dose of simvastatin (20 mg/die in the perspective of the Italian National Health Service. We identified and quantified medical costs: drug costs according to the Italian National Therapeutic Formulary and hospitalizations were quantified based on the Italian National Health Service tariffs (2006. Effects were measured in terms of mortality and morbidity reduction (number of deaths, life years gained and frequency of hospitalizations. We considered an observation period of 4.8 years. The costs borne after the first 12 months were discounted using an annual rate of 3%. We conducted one and multi-way sensitivity analyses on unit cost and effectiveness. We also conducted a threshold analysis. Results: the cost of simvastatin or atorvastatin therapy over the 4.8 years period amounted to approximately 2.3 millions euro and 2.6 millions euro per 1,000 patients respectively. Atorvastatin was more efficacious compared to simvastatin and the overall cost of care per 1,000 patients over 4.8 years of follow-up was estimated at 4.3 millions euro in the simvastatin and 4,18 millions euro in the atorvastatin group, resulting into a cost saving of 121,518 euro that is 2.8% of total costs occurred in the simvastatin group. Discussion: this study is the first economic

  4. Leaders' smiles reflect cultural differences in ideal affect.

    Science.gov (United States)

    Tsai, Jeanne L; Ang, Jen Ying Zhen; Blevins, Elizabeth; Goernandt, Julia; Fung, Helene H; Jiang, Da; Elliott, Julian; Kölzer, Anna; Uchida, Yukiko; Lee, Yi-Chen; Lin, Yicheng; Zhang, Xiulan; Govindama, Yolande; Haddouk, Lise

    2016-03-01

    Cultures differ in the emotions they teach their members to value ("ideal affect"). We conducted 3 studies to examine whether leaders' smiles reflect these cultural differences in ideal affect. In Study 1, we compared the smiles of top-ranked American and Chinese government leaders, chief executive officers, and university presidents in their official photos. Consistent with findings that Americans value excitement and other high-arousal positive states more than Chinese, American top-ranked leaders (N = 98) showed more excited smiles than Chinese top-ranked leaders (N = 91) across occupations. In Study 2, we compared the smiles of winning versus losing political candidates and higher versus lower ranking chief executive officers and university presidents in the United States and Taiwan/China. American leaders (N = 223) showed more excited smiles than Taiwanese/Chinese leaders (N = 266), regardless of election outcome or ranking. In Study 3, we administered self-report measures of ideal affect in college student samples from 10 different nations (N = 1,267) and then 8 years later, coded the smiles that legislators from those nations showed in their official photos (N = 3,372). The more nations valued excitement and other high arousal positive states, the more their leaders showed excited smiles; similarly, the more nations valued calm and other low-arousal positive states, the more their leaders showed calm smiles. These results held after controlling for national differences in democratization, human development, and gross domestic product per capita. Together, these findings suggest that leaders' smiles reflect the affective states valued by their cultures. (c) 2016 APA, all rights reserved).

  5. Leaders’ Smiles Reflect Cultural Differences in Ideal Affect

    Science.gov (United States)

    Tsai, Jeanne L.; Ang, Jen Ying Zhen; Blevins, Elizabeth; Goernandt, Julia; Fung, Helene H.; Jiang, Da; Elliott, Julian; Kölzer, Anna; Uchida, Yukiko; Lee, Yi-Chen; Lin, Yicheng; Zhang, Xiulan; Govindama, Yolande; Haddouk, Lise

    2015-01-01

    Cultures differ in the emotions they teach their members to value (“ideal affect”). We conducted three studies to examine whether leaders’ smiles reflect these cultural differences in ideal affect. In Study 1, we compared the smiles of top ranked American and Chinese government leaders, chief-executive-officers (CEOs), and university presidents in their official photos. Consistent with findings that Americans value excitement and other high arousal positive states more than Chinese, American top ranked leaders (N = 98) showed more excited smiles than Chinese top ranked leaders (N = 91) across occupations. In Study 2, we compared the smiles of winning vs. losing political candidates and higher vs. lower ranking CEOs and university presidents in the US and Taiwan/China. American leaders (N = 223) showed more excited smiles than Taiwanese/Chinese leaders (N =266), regardless of election outcome or ranking. In Study 3, we administered self-report measures of ideal affect in college student samples from 10 different nations (N = 1,267) and then eight years later, coded the smiles that legislators from those nations showed in their official photos (N = 3,372). The more nations valued excitement and other high arousal positive states, the more their leaders showed excited smiles; similarly, the more nations valued calm and other low arousal positive states, the more their leaders showed calm smiles. These results held after controlling for national differences in GDP per capita, democratization, and human development. Together, these findings suggest that leaders’ smiles reflect the affective states valued by their cultures. PMID:26751631

  6. Design and control of an ideal heat-integrated distillation column (ideal HIDiC) system separating a close-boiling ternary mixture

    International Nuclear Information System (INIS)

    Huang Kejin; Shan Lan; Zhu Qunxiong; Qian Jixin

    2007-01-01

    Despite the fact that a stand-alone ideal heat-integrated distillation column (ideal HIDiC) can be thermodynamically efficient and operationally stable, the application of an ideal HIDiC system to separate a close-boiling multi-component mixture is still a challenging problem because of the possibility of strong interactions within/between the ideal HIDiCs involved. In this work, employment of two ideal HIDiCs to separate a close-boiling ternary mixture is studied in terms of static and dynamic performance. It is found that the ideal HIDiC system can be a competitive alternative with a substantial energy saving and comparable dynamic performance in comparison with its conventional counterpart. The direct sequence appears to be superior to the indirect sequence due to the relatively small vapor flow rates to the compressors. Controlling the bottom composition of the first ideal HIDiC with the pressure elevation from the stripping section to the rectifying section helps to suppress the disturbances from the feed to the second ideal HIDiC. Special caution should, however, be taken when the latent heat of the distillates is to be recovered within/between the ideal HIDiCs involved, because a positive feedback mechanism may be formed and give rise to additional difficulties in process operation

  7. Acceleration waves in non-ideal magnetogasdynamics

    Directory of Open Access Journals (Sweden)

    R. Singh

    2014-03-01

    Full Text Available The problem of propagation of acceleration waves in an unsteady inviscid non-ideal gas under the influence of magnetic field is investigated. The characteristic solution to the problem in the neighbourhood of leading characteristics has been determined. An evolution equation governing the behaviour of acceleration waves has been derived. It is shown that a linear solution in the characteristic plane exhibits non-linear behaviour in physical plane. The effect of magnetic field on the formation of shock in non-ideal gas flow with planar and cylindrical symmetry is analysed. It is noticed that all compressive waves terminate into a shock wave. Further, we also compare/contrast the nature of solution in ideal and non-ideal magnetogasdynamic regime.

  8. Improved Classification of Mammograms Following Idealized Training

    Science.gov (United States)

    Hornsby, Adam N.; Love, Bradley C.

    2014-01-01

    People often make decisions by stochastically retrieving a small set of relevant memories. This limited retrieval implies that human performance can be improved by training on idealized category distributions (Giguère & Love, 2013). Here, we evaluate whether the benefits of idealized training extend to categorization of real-world stimuli, namely classifying mammograms as normal or tumorous. Participants in the idealized condition were trained exclusively on items that, according to a norming study, were relatively unambiguous. Participants in the actual condition were trained on a representative range of items. Despite being exclusively trained on easy items, idealized-condition participants were more accurate than those in the actual condition when tested on a range of item types. However, idealized participants experienced difficulties when test items were very dissimilar from training cases. The benefits of idealization, attributable to reducing noise arising from cognitive limitations in memory retrieval, suggest ways to improve real-world decision making. PMID:24955325

  9. Improved Classification of Mammograms Following Idealized Training.

    Science.gov (United States)

    Hornsby, Adam N; Love, Bradley C

    2014-06-01

    People often make decisions by stochastically retrieving a small set of relevant memories. This limited retrieval implies that human performance can be improved by training on idealized category distributions (Giguère & Love, 2013). Here, we evaluate whether the benefits of idealized training extend to categorization of real-world stimuli, namely classifying mammograms as normal or tumorous. Participants in the idealized condition were trained exclusively on items that, according to a norming study, were relatively unambiguous. Participants in the actual condition were trained on a representative range of items. Despite being exclusively trained on easy items, idealized-condition participants were more accurate than those in the actual condition when tested on a range of item types. However, idealized participants experienced difficulties when test items were very dissimilar from training cases. The benefits of idealization, attributable to reducing noise arising from cognitive limitations in memory retrieval, suggest ways to improve real-world decision making.

  10. IDEAL Problem Solving dalam Pembelajaran Matematika

    Directory of Open Access Journals (Sweden)

    Eny Susiana

    2012-01-01

    Full Text Available Most educators agree that problem solving is among the most meaningful and importantkinds of learning and thingking. That is, the central focus of learning and instructionshould be learning to solve problems. There are several warrants supporting that claims.They are authenticity, relevance, problem solving engages deeper learning angtherefore enhances meaning making, and constructed to represent problems (problemsolving is more meaningful. It is the reason why we must provide teaching and learningto make student’s problem solving skill in progress. There are many informationprocessingmodels of problem solving, such as simplified model of the problem-solvingprocess by Gicks, Polya’s problem solving process etc. One of them is IDEAL problemsolving. Each letter of IDEAL is stand for an aspect of thinking that is important forproblem solving. IDEAL is identify problem, Define Goal, Explore possible strategies,Anticipate outcme and Act, and Look back and learn. Using peer interaction andquestion prompt in small group in IDEAL problem solving teaching and Learning canimprove problem solving skill.Kata kunci: IDEAL Problem Solving, Interaksi Sebaya, Pertanyaan Penuntun, KelompokKecil.

  11. Idealized mixing impacts

    International Nuclear Information System (INIS)

    Peterson, R.A.

    1999-01-01

    The dispersion of tetraphenylborate in continuous stirred tank reactors plays a significant role in the utility achieved from the tetraphenylborate. Investigating idealized mixing of the materials can illuminate how this dispersion occurs

  12. Investigation of the diffusion of a massive particle in a one-dimensional ideal gas

    International Nuclear Information System (INIS)

    Khazin, M.L.

    1987-01-01

    Numerical methods have been used to investigate the dependence of the diffusion coefficient of a massive particle in a one-dimensional ideal gas on its mass. It is shown that the lower limit for the diffusion coefficient obtained by Sinai and Soloveichick and Szasz and Toth is a greatest lower bound. In addition, application of Pearson's x 2 test showed that the limit distribution of a massive particle is not Gaussian with a high significance level

  13. Spin interaction with an ideal fermi gas

    International Nuclear Information System (INIS)

    Aizenstadt, V.V.; Malyshev, V.A.

    1987-01-01

    The authors consider the equilibrium dynamics of a system consisting of a spin interacting with an ideal Fermi gas on the lattice Z/sup v, v ≥ 3. They present two examples; when this system is unitarily equivalent to an ideal Fermi gas or to a spin in an ideal Fermi gas without interactions between them

  14. Idealization of The Real Stirling Cycle

    Directory of Open Access Journals (Sweden)

    Červenka Libor

    2016-12-01

    Full Text Available The paper presents a potential idealization of the real Stirling cycle. This idealization is performed by modifying the piston movement corresponding to the ideal Stirling cycle. The focus is on the cycle thermodynamics with respect to the indicated efficiency and indicated power. A detailed 1-D simulation model of a Stirling engine is used as a tool for this assessment. The model includes real non-zero volumes of heater, regenerator, cooler and connecting pipe. The model is created in the GT Power commercial simulation software.

  15. Fuzzy implicative hyper BCK-ideals of hyper BCK-algebras

    OpenAIRE

    Jun, Young Bae; Shim, Wook Hwan

    2002-01-01

    We consider the fuzzification of the notion of implicative hyper BCK-ideals, and then investigate several properties. Using the concept of level subsets, we give a characterization of a fuzzy implicative hyper BCK-ideal. We state a relation between a fuzzy hyper BCK-ideal and a fuzzy implicative hyper BCK-ideal. We establish a condition for a fuzzy hyper BCK-ideal to be a fuzzy implicative hyper BCK-ideal. Finally, we introduce the notion of hyper homomorphisms of hyper ...

  16. Negotiated media effects. Peer feedback modifies effects of media's thin-body ideal on adolescent girls.

    Science.gov (United States)

    Veldhuis, Jolanda; Konijn, Elly A; Seidell, Jacob C

    2014-02-01

    The present study introduces a theoretical framework on negotiated media effects. Specifically, we argue that feedback of peers on thin-body ideal media images and individual dispositions guide effects on adolescent girls' psychosocial responses to media exposure. Therefore, we examined the thin-body ideal as portrayed in media and peers' feedback on such thin-ideal images in their combined effects on adolescent girls' body dissatisfaction, objectified body consciousness, and social comparison with media models. Hence, media models and peer comments were systematically combined as incorporated entities in YouTube-formats. Hypotheses were tested in a 3 (media models: extremely thin vs. thin vs. normal weight)×3 (peer comments: 6kg-underweight vs. 3kg-underweight vs. normal-weight)×2 (appearance schematicity: lower vs. higher) between-subjects design (N=216). Results showed that peer comments indicating that a media model was 'only 3kg-underweight' exerted most negative responses, particularly in girls who strongly process appearance relevant information. Peer feedback interacts with media models in guiding perceptions of what is considered an 'ideal' body shape. Results highlight the important role of peers as well as individual predispositions in view of understanding how thin-ideal media images may impact adolescent girls' body image concerns. Copyright © 2013 Elsevier Ltd. All rights reserved.

  17. INTERVAL-VALUED INTUITIONISTIC FUZZY BI-IDEALS IN TERNARY SEMIRINGS

    Directory of Open Access Journals (Sweden)

    D. KRISHNASWAMY

    2016-04-01

    Full Text Available In this paper we introduce the notions of interval-valued fuzzy bi-ideal, interval-valued anti fuzzy bi-ideal and interval-valued intuitionistic fuzzy bi-ideal in ternary semirings and some of the basic properties of these ideals are investigated. We also introduce normal interval-valued intuitionistic fuzzy ideals in ternary semirings.

  18. Number of test trials needed for performance stability and interrater reliability of the one leg stand test in patients with a major non-traumatic lower limb amputation

    DEFF Research Database (Denmark)

    Kristensen, Morten Tange; Nielsen, Anni Østergaard; Madsen Topp, Ulla

    2014-01-01

    Balance is beneficial for daily functioning of patients with a lower limb amputation and sometimes assessed by the one-leg stand test (OLST). The aims of the study were to examine (1) the number of trials needed to achieve performance stability, (2) the interrater reliability of the OLST in patie......Balance is beneficial for daily functioning of patients with a lower limb amputation and sometimes assessed by the one-leg stand test (OLST). The aims of the study were to examine (1) the number of trials needed to achieve performance stability, (2) the interrater reliability of the OLST...... in patients with a major non-traumatic lower limb amputation, and (3) to provide a test procedure....

  19. Two-Step Condensation of the Ideal Bose Gas in Highly Anisotropic Traps

    International Nuclear Information System (INIS)

    van Druten, N.J.; Ketterle, W.

    1997-01-01

    The ideal Bose gas in a highly anisotropic harmonic potential is studied. It is found that Bose-Einstein condensation occurs in two distinct steps as the temperature is lowered. In the first step the specific heat shows a sharp feature, but the system still occupies many one-dimensional quantum states. In the second step, at a significantly lower temperature, the ground state becomes macroscopically occupied. It should be possible to verify these predictions using present-day atom traps. The two-step behavior can occur in a rather general class of anisotropic traps, including the box potential. copyright 1997 The American Physical Society

  20. Finite element limit loads for non-idealized through-wall cracks in thick-walled pipe

    International Nuclear Information System (INIS)

    Shim, Do-Jun; Han, Tae-Song; Huh, Nam-Su

    2013-01-01

    Highlights: • The lower bound bulging factor of thin-walled pipe can be used for thick-walled pipe. • The limit loads are proposed for thick-walled, transition through-wall cracked pipe. • The correction factors are proposed for estimating limit loads of transition cracks. • The limit loads of short transition cracks are similar to those of idealized cracks. - Abstract: The present paper provides plastic limit loads for non-idealized through-wall cracks in thick-walled pipe. These solutions are based on detailed 3-dimensional finite element (FE) analyses which can be used for structural integrity assessment of nuclear piping. To cover a practical range of interest, the geometric variables and loading conditions affecting the plastic limit loads of thick-walled pipe with non-idealized through-wall cracks were systematically varied. In terms of crack orientation, both circumferential and axial through-wall cracks were considered. As for loading conditions, axial tension, global bending, and internal pressure were considered for circumferential cracks, whereas only internal pressure was considered for axial cracks. Furthermore, the values of geometric factor representing shape characteristics of non-idealized through-wall cracks were also systematically varied. In order to provide confidence in the present FE analyses results, plastic limit loads of un-cracked, thick-walled pipe resulting from the present FE analyses were compared with the theoretical solutions. Finally, correction factors to the idealized through-wall crack solutions were developed to determine the plastic limit loads of non-idealized through-wall cracks in thick-walled pipe

  1. Family Life and Developmental Idealism in Yazd, Iran

    Directory of Open Access Journals (Sweden)

    Mohammad Jalal Abbasi-Shavazi

    2012-03-01

    Full Text Available BACKGROUND This paper is motivated by the theory that developmental idealism has been disseminated globally and has become an international force for family and demographic change. Developmental idealism is a set of cultural beliefs and values about development and how development relates to family and demographic behavior. It holds that modern societies are causal forces producing modern families, that modern families help to produce modern societies, and that modern family change is to be expected. OBJECTIVE We examine the extent to which developmental idealism has been disseminated in Iran. We also investigate predictors of the dissemination of developmental idealism. METHODS We use survey data collected in 2007 from a sample of women in Yazd, a city in Iran. We examine the distribution of developmental idealism in the sample and the multivariate predictors of developmental idealism. RESULTS We find considerable support for the expectation that many elements of developmental idealism have been widely disseminated. Statistically significant majorities associate development with particular family attributes, believe that development causes change in families, believe that fertility reductions and age-at-marriage increases help foster development, and perceive family trends in Iran headed toward modernity. As predicted, parental education, respondent education, and income affect adherence to developmental idealism. CONCLUSIONS Developmental idealism has been widely disseminated in Yazd, Iran and is related to social and demographic factors in predicted ways. COMMENTS Although our data come from only one city, we expect that developmental idealism has been widely distributed in Iran, with important implications for family and demographic behavior.

  2. Results of a prospective randomized controlled trial of early ambulation for patients with lower extremity autografts.

    Science.gov (United States)

    Lorello, David John; Peck, Michael; Albrecht, Marlene; Richey, Karen J; Pressman, Melissa A

    2014-01-01

    It is common practice to keep those patients with lower extremity autografts immobile until post-operative day (POD) 5. There is however inherent risks associated with even short periods of immobility. As of now there are no randomized controlled trials looking at early ambulation of patients with lower extremity autografts in the burn community.The objective of this study was to show that patients who begin ambulation within 24 hours of lower extremity autografting will have no increased risk of graft failure than those patients who remain immobile until POD 5. Thirty-one subjects who received autografts to the lower extremity were randomized after surgery into either the early ambulation group (EAG;17 subjects) or the standard treatment group (STG;14 subjects). Those subjects randomized to the EAG began ambulating with physical therapy on POD 1. Subjects in the STG maintained bed rest until POD 5. There was no difference in the number of patients with graft loss in either the EAG or STG on POD 5, and during any of the follow-up visits. No subjects required regrafting. There was a significant difference in the mean minutes of ambulation, with the EAG ambulating longer than the STG (EAG 23.4 minutes [SD 12.03], STG 14.1 [SD 9.00], P=.0235) on POD 5. Burn patients with lower extremity autografts can safely ambulate on POD 1 without fear of graft failure compared with those patients that remain on bed rest for 5 days.

  3. Effect of beetroot juice on lowering blood pressure in free-living, disease-free adults: a randomized, placebo-controlled trial

    Directory of Open Access Journals (Sweden)

    Coles Leah T

    2012-12-01

    Full Text Available Abstract Background The consumption of beetroot juice on a low nitrate diet may lower blood pressure (BP and therefore reduce the risk of cardiovascular events. However, it is unknown if its inclusion as part of a normal diet has a similar effect on BP. The aim of the study was to conduct a randomized controlled trial with free-living adults to investigate if consuming beetroot juice in addition to a normal diet produces a measureable reduction in BP. Method Fifteen women and fifteen men participated in a double-blind, randomized, placebo-controlled, crossover study. Volunteers were randomized to receive 500 g of beetroot and apple juice (BJ or a placebo juice (PL. Volunteers had BP measured at baseline and at least hourly for 24-h following juice consumption using an ambulatory blood pressure monitor (ABPM. Volunteers remained at the clinic for 1-h before resuming normal non-strenuous daily activities. The identical procedure was repeated 2-wk later with the drink (BJ or PL not consumed on the first visit. Results Overall, there was a trend (P=0.064 to lower systolic blood pressure (SBP at 6-h after drinking BJ relative to PL. Analysis in men only (n=13 after adjustment for baseline differences demonstrated a significant (P Conclusions Beetroot juice will lower BP in men when consumed as part of a normal diet in free-living healthy adults. Trial registration anzctr.org.au ACTRN12612000445875

  4. Improved reconstruction for IDEAL spiral CSI

    DEFF Research Database (Denmark)

    Hansen, Rie Beck; Mariager, Christian; Laustsen, Christoffer

    2017-01-01

    In this study we demonstrate how reconstruction for IDEAL spiral CSI (spectroscopic imaging scheme developed for hyperpolarized dynamic metabolic MR imaging) can be improved by using regularization with a sparsity constraint. By exploiting sparsity of the spectral domain, IDEAL spiral CSI can...

  5. What is an attractive body? Using an interactive 3D program to create the ideal body for you and your partner.

    Directory of Open Access Journals (Sweden)

    Kara L Crossley

    Full Text Available What is the ideal body size and shape that we want for ourselves and our partners? What are the important physical features in this ideal? And do both genders agree on what is an attractive body? To answer these questions we used a 3D interactive software system which allows our participants to produce a photorealistic, virtual male or female body. Forty female and forty male heterosexual Caucasian observers (females mean age 19.10 years, s.d. 1.01; 40 males mean age 19.84, s.d. 1.66 set their own ideal size and shape, and the size and shape of their ideal partner using the DAZ studio image manipulation programme. In this programme the shape and size of a 3D body can be altered along 94 independent dimensions, allowing each participant to create the exact size and shape of the body they want. The volume (and thus the weight assuming a standard density and the circumference of the bust, waist and hips of these 3D models can then be measured. The ideal female body set by women (BMI = 18.9, WHR = 0.70, WCR = 0.67 was very similar to the ideal partner set by men, particularly in their BMI (BMI = 18.8, WHR = 0.73, WCR = 0.69. This was a lower BMI than the actual BMI of 39 of the 40 women. The ideal male body set by the men (BMI = 25.9, WHR = 0.87, WCR = 0.74 was very similar to the ideal partner set by the women (BMI = 24.5, WHR = 0.86, WCR = 0.77. This was a lower BMI than the actual BMI of roughly half of the men and a higher BMI than the other half. The results suggest a consistent preference for an ideal male and female body size and shape across both genders. The results also suggest that both BMI and torso shape are important components for the creation of the ideal body.

  6. Effect of increasing doses of saw palmetto extract on lower urinary tract symptoms: a randomized trial.

    Science.gov (United States)

    Barry, Michael J; Meleth, Sreelatha; Lee, Jeannette Y; Kreder, Karl J; Avins, Andrew L; Nickel, J Curtis; Roehrborn, Claus G; Crawford, E David; Foster, Harris E; Kaplan, Steven A; McCullough, Andrew; Andriole, Gerald L; Naslund, Michael J; Williams, O Dale; Kusek, John W; Meyers, Catherine M; Betz, Joseph M; Cantor, Alan; McVary, Kevin T

    2011-09-28

    Saw palmetto fruit extracts are widely used for treating lower urinary tract symptoms attributed to benign prostatic hyperplasia (BPH); however, recent clinical trials have questioned their efficacy, at least at standard doses (320 mg/d). To determine the effect of saw palmetto extract (Serenoa repens, from saw palmetto berries) at up to 3 times the standard dose on lower urinary tract symptoms attributed to BPH. A double-blind, multicenter, placebo-controlled randomized trial at 11 North American clinical sites conducted between June 5, 2008, and October 10, 2010, of 369 men aged 45 years or older, with a peak urinary flow rate of at least 4 mL/s, an American Urological Association Symptom Index (AUASI) score of between 8 and 24 at 2 screening visits, and no exclusions. One, 2, and then 3 doses (320 mg/d) of saw palmetto extract or placebo, with dose increases at 24 and 48 weeks. Difference in AUASI score between baseline and 72 weeks. Secondary outcomes included measures of urinary bother, nocturia, peak uroflow, postvoid residual volume, prostate-specific antigen level, participants' global assessments, and indices of sexual function, continence, sleep quality, and prostatitis symptoms. Between baseline and 72 weeks, mean AUASI scores decreased from 14.42 to 12.22 points (-2.20 points; 95% CI, -3.04 to -1.36) [corrected]with saw palmetto extract and from 14.69 to 11.70 points (-2.99 points; 95% CI, -3.81 to -2.17) with placebo. The group mean difference in AUASI score change from baseline to 72 weeks between the saw palmetto extract and placebo groups was 0.79 points favoring placebo (upper bound of the 1-sided 95% CI most favorable to saw palmetto extract was 1.77 points, 1-sided P = .91). Saw palmetto extract was no more effective than placebo for any secondary outcome. No clearly attributable adverse effects were identified. Increasing doses of a saw palmetto fruit extract did not reduce lower urinary tract symptoms more than placebo. clinicaltrials

  7. Asymptotic sequences over ideals and projectively equivalent ideals with respect to modules

    International Nuclear Information System (INIS)

    Naghipour, R.; Sedghi, M.

    2007-09-01

    Let R be a commutative Noetherian ring, and let N be a non-zero finitely generated R-module. The purpose of this paper is to show that if I and J are projectively equivalent ideals w.r.t. N, then a sequence x := x 1 , . . . , x n of elements of R is an asymptotic sequence over I w.r.t. N if and only if it is an asymptotic sequence over J w.r.t. N. Also, it is shown that if R is local, then the lengths of all maximal asymptotic sequences over an ideal I w.r.t. N are the same. As a consequence we derive a generalization of Rees' theorem. (author)

  8. Quantum surface tension in ideal gases

    International Nuclear Information System (INIS)

    Sisman, A.

    2005-01-01

    Due to wave character of atoms, an ideal gas confined in a finite domain exhibits Casimir like size effects. These effects become appreciable in a domain with at least one dimension in the order of micron. On this scale, thermodynamic state functions of an ideal gas become shape and size dependent and some new effects appear. In the literature, only some domains of regular shapes have been considered. In this study, the results are generalized to a domain of an arbitrary shape by using Weyl s conjecture for density of states. It is seen that free energy expression of an ideal Maxwellian gas consists of a classical volume dependent term and also a quantum originated surface dependent term, which causes a quantum surface tension. In a rectangular box filled by an ideal gas and separated by a movable wall into two parts, it is shown that a lateral force appears on the movable wall due to quantum surface tension

  9. The Statistical Mechanics of Ideal MHD Turbulence

    Science.gov (United States)

    Shebalin, John V.

    2003-01-01

    Turbulence is a universal, nonlinear phenomenon found in all energetic fluid and plasma motion. In particular. understanding magneto hydrodynamic (MHD) turbulence and incorporating its effects in the computation and prediction of the flow of ionized gases in space, for example, are great challenges that must be met if such computations and predictions are to be meaningful. Although a general solution to the "problem of turbulence" does not exist in closed form, numerical integrations allow us to explore the phase space of solutions for both ideal and dissipative flows. For homogeneous, incompressible turbulence, Fourier methods are appropriate, and phase space is defined by the Fourier coefficients of the physical fields. In the case of ideal MHD flows, a fairly robust statistical mechanics has been developed, in which the symmetry and ergodic properties of phase space is understood. A discussion of these properties will illuminate our principal discovery: Coherent structure and randomness co-exist in ideal MHD turbulence. For dissipative flows, as opposed to ideal flows, progress beyond the dimensional analysis of Kolmogorov has been difficult. Here, some possible future directions that draw on the ideal results will also be discussed. Our conclusion will be that while ideal turbulence is now well understood, real turbulence still presents great challenges.

  10. On Classical Ideal Gases

    Directory of Open Access Journals (Sweden)

    Laurent Chusseau

    2013-02-01

    Full Text Available We show that the thermodynamics of ideal gases may be derived solely from the Democritean concept of corpuscles moving in vacuum plus a principle of simplicity, namely that these laws are independent of the laws of motion, aside from the law of energy conservation. Only a single corpuscle in contact with a heat bath submitted to a z and t-invariant force is considered. Most of the end results are known but the method appears to be novel. The mathematics being elementary, the present paper should facilitate the understanding of the ideal gas law and of classical thermodynamics even though not-usually-taught concepts are being introduced.

  11. Predicting film genres with implicit ideals

    Directory of Open Access Journals (Sweden)

    Andrew McGregor Olney

    2013-01-01

    Full Text Available We present a new approach to defining film genre based on implicit ideals. When viewers rate the likability of a film, they indirectly express their ideal of what a film should be. Across six studies we investigate the category structure that emerges from likability ratings and the category structure that emerges from the features of film. We further compare these data-driven category structures with human annotated film genres. We conclude that film genres are structured more around ideals than around features of film. This finding lends experimental support to the notion that film genres are set of shifting, fuzzy, and highly contextualized psychological categories.

  12. Predicting film genres with implicit ideals.

    Science.gov (United States)

    Olney, Andrew McGregor

    2012-01-01

    We present a new approach to defining film genre based on implicit ideals. When viewers rate the likability of a film, they indirectly express their ideal of what a film should be. Across six studies we investigate the category structure that emerges from likability ratings and the category structure that emerges from the features of film. We further compare these data-driven category structures with human annotated film genres. We conclude that film genres are structured more around ideals than around features of film. This finding lends experimental support to the notion that film genres are set of shifting, fuzzy, and highly contextualized psychological categories.

  13. Certain Solutions Of Shock-Waves In Non-Ideal Gases

    Directory of Open Access Journals (Sweden)

    Kanti Pandey

    2016-05-01

    Full Text Available In present paper non similar solutions for plane, cylindrical and spherical unsteady flows of non-ideal gas behind shock wave of arbitrary strength initiated by the instantaneous release of finite energy and propagating in a non-ideal gas is investigated. Asymptotic analysis is applied to obtain a solution up to second order. Solution for numerical calculation Runga-Kutta method of fourth order is applied and is concluded that for non-ideal case there is a decrease in velocity, pressure and density for 0th and IInd order in comparison to ideal gas but a increasing tendency in velocity, pressure and density for Ist order in comparison to ideal gas. The energy of explosion J0 for ideal gas is greater in comparison to non-ideal gas for plane, cylindrical and spherical waves.

  14. Arithmetically Related Ideal Topologies and the Infinitude of Primes ...

    African Journals Online (AJOL)

    algebra. Mathematics Subject Classification (1991): 11N80, 11N25, 11A41, 11T99, 13A15, 20M25 Keywords: x-ideal, topological semigroup, ideal topology, infinitude of primes, generalized primes and integers, distribution, integers, specified multiplicative constraints, primes, ideals, multiplicative ideal theory, semigroup

  15. Role of blood pressure and other variables in the differential cardiovascular event rates noted in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA)

    DEFF Research Database (Denmark)

    Poulter, Neil R; Wedel, Hans; Dahlöf, Björn

    2005-01-01

    Results of the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA) show significantly lower rates of coronary and stroke events in individuals allocated an amlodipine-based combination drug regimen than in those allocated an atenolol-based combination drug regimen (HR...

  16. Effect of Uric Acid Lowering on Renin-Angiotensin-System Activation and Ambulatory BP: A Randomized Controlled Trial.

    Science.gov (United States)

    McMullan, Ciaran J; Borgi, Lea; Fisher, Naomi; Curhan, Gary; Forman, John

    2017-05-08

    Higher serum uric acid levels, even within the reference range, are strongly associated with increased activity of the renin-angiotensin system (RAS) and risk of incident hypertension. However, the effect of lowering serum uric acid on RAS activity in humans is unknown, although the data that lowering serum uric acid can reduce BP are conflicting. In a double-blind placebo-controlled trial conducted from 2011 to 2015, we randomly assigned 149 overweight or obese adults with serum uric acid ≥5.0 mg/dl to uric acid lowering with either probenecid or allopurinol, or to placebo. The primary endpoints were kidney-specific and systemic RAS activity. Secondary endpoints included mean 24-hour systolic BP, mean awake and asleep BP, and nocturnal dipping. Allopurinol and probenecid markedly lowered serum uric acid after 4 and 8 weeks compared with placebo (mean serum uric acid in allopurinol, probenecid, and placebo at 8 weeks was 2.9, 3.5, and 5.6 mg/dl, respectively). The change in kidney-specific RAS activity, measured as change in the median (interquartile range) renal plasma flow response to captopril (in ml/min per 1.73 m 2 ) from baseline to 8 weeks, was -4 (-25 to 32) in the probenecid group ( P =0.83), -4 (-16 to 9) in the allopurinol group ( P =0.32), and 1 (-21 to 17) in the placebo group ( P =0.96), with no significant treatment effect ( P =0.77). Similarly, plasma renin activity and plasma angiotensin II levels did not significantly change with treatment. The change in mean (±SD) 24-hour systolic BPs from baseline to 8 weeks was -1.6±10.1 with probenecid ( P =0.43), -0.4±6.1 with allopurinol ( P =0.76), and 0.5±6.0 with placebo ( P =0.65); there was no significant treatment effect ( P =0.58). Adverse events occurred in 9%, 12%, and 2% of those given probenecid, allopurinol, or placebo, respectively. In contrast to animal experiments and observational studies, this randomized, placebo-controlled trial found that uric acid lowering had no effect on kidney

  17. IDEAL STRUCTURE OF UNIFORM ROE ALGEBRAS OVER SIMPLE CORES

    Institute of Scientific and Technical Information of China (English)

    CHEN XIAOMAN; WANG QIN

    2004-01-01

    This paper characterizes ideal structure of the uniform Roe algebra B* (X) over sinple cores X. A necessary and sufficient condition for a principal ideal of B*(X) to be spatial is given and an example of non-spatial ideal of B* (X) is constructed. By establishing an one-one correspondence between the ideals of B* (X) and the ω-filters on X, the maximal ideals of B* (X) are completely described by the corona of the Stone-Cech compactification of X.

  18. Active ideal sedimentation: exact two-dimensional steady states.

    Science.gov (United States)

    Hermann, Sophie; Schmidt, Matthias

    2018-02-28

    We consider an ideal gas of active Brownian particles that undergo self-propelled motion and both translational and rotational diffusion under the influence of gravity. We solve analytically the corresponding Smoluchowski equation in two space dimensions for steady states. The resulting one-body density is given as a series, where each term is a product of an orientation-dependent Mathieu function and a height-dependent exponential. A lower hard wall is implemented as a no-flux boundary condition. Numerical evaluation of the suitably truncated analytical solution shows the formation of two different spatial regimes upon increasing Peclet number. These regimes differ in their mean particle orientation and in their variation of the orientation-averaged density with height.

  19. Randomized, placebo-controlled trial of mipomersen in patients with severe hypercholesterolemia receiving maximally tolerated lipid-lowering therapy.

    Directory of Open Access Journals (Sweden)

    Mary P McGowan

    Full Text Available Mipomersen, an antisense oligonucleotide targeting apolipoprotein B synthesis, significantly reduces LDL-C and other atherogenic lipoproteins in familial hypercholesterolemia when added to ongoing maximally tolerated lipid-lowering therapy. Safety and efficacy of mipomersen in patients with severe hypercholesterolemia was evaluated.Randomized, double-blind, placebo-controlled, multicenter trial. Patients (n  = 58 were ≥18 years with LDL-C ≥7.8 mmol/L or LDL-C ≥5.1 mmol/L plus CHD disease, on maximally tolerated lipid-lowering therapy that excluded apheresis. Weekly subcutaneous injections of mipomersen 200 mg (n  = 39 or placebo (n  = 19 were added to lipid-lowering therapy for 26 weeks.percent reduction in LDL-C from baseline to 2 weeks after the last dose of treatment. Mipomersen (n = 27 reduced LDL-C by 36%, from a baseline of 7.2 mmol/L, for a mean absolute reduction of 2.6 mmol/L. Conversely, mean LDL-C increased 13% in placebo (n = 18 from a baseline of 6.5 mmol/L (mipomersen vs placebo p<0.001. Mipomersen produced statistically significant (p<0.001 reductions in apolipoprotein B and lipoprotein(a, with no change in high-density lipoprotein cholesterol. Mild-to-moderate injection site reactions were the most frequently reported adverse events with mipomersen. Mild-to-moderate flu-like symptoms were reported more often with mipomersen. Alanine transaminase increase, aspartate transaminase increase, and hepatic steatosis occurred in 21%, 13% and 13% of mipomersen treated patients, respectively. Adverse events by category for the placebo and mipomersen groups respectively were: total adverse events, 16(84.2%, 39(100%; serious adverse events, 0(0%, 6(15.4%; discontinuations due to adverse events, 1(5.3%, 8(20.5% and cardiac adverse events, 1(5.3%, 5(12.8%.Mipomersen significantly reduced LDL-C, apolipoprotein B, total cholesterol and non-HDL-cholesterol, and lipoprotein(a. Mounting evidence suggests it may be a

  20. Analysis of an ideal amorphous solid

    International Nuclear Information System (INIS)

    To, L.T.; Stachurski, Z.H.

    2004-01-01

    Full text: In geometrical terms, amorphous solids are fundamentally different from crystalline solids in that they can not be constructed by the crystallographic method of translation of the basis along a lattice. Therefore, to study amorphous structures we must invoke concepts and use measures different to those used for ordered structures. Nevertheless, an ideal amorphous solid must share together with the ideal crystalline solid in the same definition of the term 'ideal'. In both cases it must be a perfect body, in which perfection is carried through in every detail to an unlimited (infinite) size without fault or defect. The latest results on this research will be presented. To qualify for a solid, rigid body, close packing of the spheres is required. For an ideal amorphous solids composed of hard spheres of identical size, we impose a stricter condition for the packing, namely, to be such that all spheres are in fixed positions (no loose spheres). To define the ideal solid, we must define what we mean by a perfect amorphous structure. Here, perfection is defined by, first the definition of imperfections, and next by the requirement of absence of imperfections of any kind. We envisage two types of defects: (i) geometrical, and (ii) statistical. Geometrical defects are: a sphere of different size, a loose sphere, and a vacancy. A statistical defect is defined with respect to two statistical functions: Ψ(N C ), and Φ(S β ). The former describes the probability of a given sphere having nc number of touching contacts, and the latter describes the disposition of the contacts on the surface of the sphere. Defects relating to the two functions will be described. The results for the functions, Ψ(N C ), and Φ(S β ), for the corresponding radial distribution function, and so called blocking number will be presented from simulations of an ideal amorphous solid

  1. Health Insurance Status as a Barrier to Ideal Cardiovascular Health for U.S. Adults: Data from the National Health and Nutrition Examination Survey (NHANES.

    Directory of Open Access Journals (Sweden)

    Michael A McClurkin

    Full Text Available Little is known about the association between cardiovascular (CV health and health insurance status. We hypothesized that U.S. adults without health insurance coverage would have a lower likelihood of ideal cardiovascular health.Using National Health and Nutrition Examination Survey (NHANES data from 2007-2010, we examined the relationship between health insurance status and ideal CV health in U.S. adults aged ≥19 years and <65 (N = 3304. Ideal CV health was defined by the American Heart Association (AHA as the absence of clinically manifested CV disease and the simultaneous presence of 6-7 "ideal" CV health factors and behaviors. Logistic regression modeling was used to determine the relationship between health insurance status and the odds of ideal CV health. Of the U.S. adult population, 5.4% attained ideal CV health, and 23.5% were without health insurance coverage. Those without health insurance coverage were more likely to be young (p<0.0001, male (p<0.0001, non-white (p<0.0001, with less than a high school degree (p<0.0001, have a poverty-to-income ratio less than 1 (p<0.0001 and unemployed (p<0.0001 compared to those with coverage. Lack of health insurance coverage was associated with a lower likelihood of ideal CV health; however, this relationship was attenuated by socioeconomic status.U.S. adults without health insurance coverage are less likely to have ideal CV health. Population-based strategies and interventions directed at the community-level may be one way to improve overall CV health and reach this at-risk group.

  2. EDUCATIONAL IDEAL OF UKRAINIAN ETHNOPEDAGOGIES: CARPATHIAN VECTOR

    Directory of Open Access Journals (Sweden)

    Nelly Lysenko

    2015-04-01

    Full Text Available Educational ideal, methods, forms and means of folk-educational influence on its formation, starting from the first years of baby’s life are topical problems for researchers. The main element is an aim. The aim is an ideal image of the expecting result which is regarded as a guide for the educational activity of a certain ethnic community. The content of the notion of educational ideal is the imagery about the most important qualities of a personality, their manners, culture of relationship in the society, behavior. Ukrainian mentality is practicality, rationality, generosity, intellect in general. It is fully reflected in the pedagogical aim. At the same time mental means spiritual. That is something in thoughts and intents of a person. It is important to emphasize that Ukrainian ethos was formed on the basis of several groups, not only having formed a nation, but also having synthesized the temperament, traditions and customs, clothes and everyday life, culture in general. Hutsul, Boyko, Lemko (121 ethnic groups all together differ by the uniqueness of the appearance. At the same time their internal essence, that is educational ideal, world view, ethic morals, are unchangeable. Educational ideal is historically determined. Esthetic strategies, formation of creativity, development of the abilities by the means of folk crafts and trades, upbringing of a host pierce through the educational ideal of nowadays Ukrainians. The people aim to bring up their children as true citizens: good kids mean quiet old age, while with evil children old age becomes a hell. Thus, the educational ideal of the Ukrainians should be considered as a basis for modern educational technologies projection.

  3. The Ideal Man and Woman According to University Students

    Science.gov (United States)

    Weinstein, Lawrence; Laverghetta, Antonio V.; Peterson, Scott A.

    2009-01-01

    The present study determined if the ideal man has changed over the years and who and what the ideal woman is. We asked students at Cameron University to rate the importance of character traits that define the ideal man and woman. Subjects also provided examples of famous people exemplifying the ideal, good, average, and inferior man and woman. We…

  4. Extra-Training I-deals

    DEFF Research Database (Denmark)

    Elgoibar, Patricia; Lindholst, Morten

    2016-01-01

    illustrates the negotiation process between a team manager at TNK - a leading multinational software development company- and one of his team members. The employee is willing to negotiate an I-deal with the objective of attending a training course abroad. This case is a two-party employment deal-making......, and professionals; as well as in students from different cultural backgrounds. The feedback from the students shows a clear understanding of the information described in the test as well as a satisfactory learning experience in the concept of I-deals terms, understanding of the concept of BATNA in negotiation......, and the importance of taking into account the interests of the other party and parties when negotiating this type of agreements....

  5. Estimation of the Ideal Binary Mask using Directional Systems

    DEFF Research Database (Denmark)

    Boldt, Jesper; Kjems, Ulrik; Pedersen, Michael Syskind

    2008-01-01

    The ideal binary mask is often seen as a goal for time-frequency masking algorithms trying to increase speech intelligibility, but the required availability of the unmixed signals makes it difficult to calculate the ideal binary mask in any real-life applications. In this paper we derive the theory...... and the requirements to enable calculations of the ideal binary mask using a directional system without the availability of the unmixed signals. The proposed method has a low complexity and is verified using computer simulation in both ideal and non-ideal setups showing promising results....

  6. Intensive versus Guideline Blood Pressure and Lipid Lowering in Patients with Previous Stroke: Main Results from the Pilot ‘Prevention of Decline in Cognition after Stroke Trial’ (PODCAST) Randomised Controlled Trial

    Science.gov (United States)

    Scutt, Polly; Blackburn, Daniel J.; Ankolekar, Sandeep; Krishnan, Kailash; Ballard, Clive; Burns, Alistair; Mant, Jonathan; Passmore, Peter; Pocock, Stuart; Reckless, John; Sprigg, Nikola; Stewart, Rob; Wardlaw, Joanna M.; Ford, Gary A.

    2017-01-01

    Background Stroke is associated with the development of cognitive impairment and dementia. We assessed the effect of intensive blood pressure (BP) and/or lipid lowering on cognitive outcomes in patients with recent stroke in a pilot trial. Methods In a multicentre, partial-factorial trial, patients with recent stroke, absence of dementia, and systolic BP (SBP) 125–170 mmHg were assigned randomly to at least 6 months of intensive (target SBP Addenbrooke’s Cognitive Examination-Revised (ACE-R). Results We enrolled 83 patients, mean age 74.0 (6.8) years, and median 4.5 months after stroke. The median follow-up was 24 months (range 1–48). Mean BP was significantly reduced with intensive compared to guideline treatment (difference –10·6/–5·5 mmHg; pcognition, intensive BP and lipid lowering were feasible and safe, but did not alter cognition over two years. The association between intensive lipid lowering and improved scores for some secondary outcomes suggests further trials are warranted. Trial Registration ISRCTN ISRCTN85562386 PMID:28095412

  7. To Be or Want to Be: Disentangling the Role of Actual versus Ideal Self in Implicit Self-Esteem

    Science.gov (United States)

    De Houwer, Jan; De Raedt, Rudi

    2014-01-01

    A growing body of work suggests that both depressed and non-depressed individuals display implicit positivity towards the self. In the current study, we examined whether this positivity can be underpinned by two qualitatively distinct propositions related to actual (‘I am good’) or ideal (‘I want to be good’) self-esteem. Dysphoric and non-dysphoric participants completed a self-esteem Implicit Association Test (IAT) as well an Implicit Relational Assessment Procedure (IRAP) targeting their actual self-esteem and an IRAP targeting ideal self-esteem. Both groups demonstrated similar and positive IAT effects. A more complex picture emerged with regard to the IRAP effects. Whereas non-dysphorics did not differ in their actual and ideal self-esteem, their dysphoric counterparts demonstrated lower actual than ideal self-esteem. Our results suggest that closer attention to the role of propositional processes in implicit measures may unlock novel insight into the relationship between implicit self-esteem and depression. PMID:25268889

  8. To be or want to be: disentangling the role of actual versus ideal self in implicit self-esteem.

    Directory of Open Access Journals (Sweden)

    Jonathan Remue

    Full Text Available A growing body of work suggests that both depressed and non-depressed individuals display implicit positivity towards the self. In the current study, we examined whether this positivity can be underpinned by two qualitatively distinct propositions related to actual ('I am good' or ideal ('I want to be good' self-esteem. Dysphoric and non-dysphoric participants completed a self-esteem Implicit Association Test (IAT as well an Implicit Relational Assessment Procedure (IRAP targeting their actual self-esteem and an IRAP targeting ideal self-esteem. Both groups demonstrated similar and positive IAT effects. A more complex picture emerged with regard to the IRAP effects. Whereas non-dysphorics did not differ in their actual and ideal self-esteem, their dysphoric counterparts demonstrated lower actual than ideal self-esteem. Our results suggest that closer attention to the role of propositional processes in implicit measures may unlock novel insight into the relationship between implicit self-esteem and depression.

  9. A randomized controlled trial to evaluate the feasibility of the Wii Fit for improving walking in older adults with lower limb amputation.

    Science.gov (United States)

    Imam, Bita; Miller, William C; Finlayson, Heather; Eng, Janice J; Jarus, Tal

    2017-01-01

    To assess the feasibility of Wii.n.Walk for improving walking capacity in older adults with lower limb amputation. A parallel, evaluator-blind randomized controlled feasibility trial. Community-living. Individuals who were ⩾50 years old with a unilateral lower limb amputation. Wii.n.Walk consisted of Wii Fit training, 3x/week (40 minute sessions), for 4 weeks. Training started in the clinic in groups of 3 and graduated to unsupervised home training. Control group were trained using cognitive games. Feasibility indicators: trial process (recruitment, retention, participants' perceived benefit from the Wii.n.Walk intervention measured by exit questionnaire), resources (adherence), management (participant processing, blinding), and treatment (adverse event, and Cohen's d effect size and variance). Primary clinical outcome: walking capacity measured using the 2 Minute Walk Test at baseline, end of treatment, and 3-week retention. Of 28 randomized participants, 24 completed the trial (12/arm). Median (range) age was 62.0 (50-78) years. Mean (SD) score for perceived benefit from the Wii.n.Walk intervention was 38.9/45 (6.8). Adherence was 83.4%. The effect sizes for the 2 Minute Walk Test were 0.5 (end of treatment) and 0.6 (3-week retention) based on intention to treat with imputed data; and 0.9 (end of treatment) and 1.2 (3-week retention) based on per protocol analysis. The required sample size for a future larger RCT was deemed to be 72 (36 per arm). The results suggested the feasibility of the Wii.n.Walk with a medium effect size for improving walking capacity. Future larger randomized controlled trials investigating efficacy are warranted.

  10. Development of pitanga nectar with different sweeteners by sensory analysis: ideal pulp dilution, ideal sweetness, and sweetness equivalence

    Directory of Open Access Journals (Sweden)

    Mírian Luisa Faria Freitas

    2014-03-01

    Full Text Available The objective of this study was to develop pitanga nectar formulations in which sucrose was replaced with different sweeteners. Consumer tests were conducted with 50 fruit juice consumers, and a just-about-right scale was used to determine the ideal pulp dilution and ideal sweetness with sucrose. Furthermore, the adequate concentrations of six sweeteners were determined to obtain the equivalent sweetness of sucrose using relative to these concentrations the magnitude estimation model with 19 selected assessors. The ideal dilution test resulted in 25% pulp, and the ideal sweetness test, 10% sucrose. Sweetener concentrations to replace sucrose were 0.0160%, 0.0541%, 0.1000%, 0.0999%, 0.0017%, and 0.0360%, respectively, for sucralose, aspartame, stevia 40% rebaudioside A, stevia 95% rebaudioside A, neotame, and a 2:1 cyclamate/saccharin blend. These results can be used to prepare pitanga nectar with different sweeteners and obtain the same sweetness intensity in less caloric products than that of nectar prepared with sucrose.

  11. Professional ideals and daily practice in journalism

    DEFF Research Database (Denmark)

    Pihl-Thingvad, Signe

    2015-01-01

    Professional ideals are crucial in terms of guiding and committing journalists in modern media organizations. But what happens if there are discrepancies between the journalists’ professional ideals and their daily working practice? Research suggests negative consequences, such as withdrawal...

  12. On the containment hierarchy for simplicial ideals

    OpenAIRE

    Lampa-Baczyńska, Magdalena; Malara, Grzegorz

    2014-01-01

    The purpose of this note is to study containment relations and asymptotic invariants for ideals of fixed codimension skeletons (simplicial ideals) determined by arrangements of $n + 1$ general hyperplanes in the $n-$dimensional projective space over an arbitrary field.

  13. Fusion rings and fusion ideals

    DEFF Research Database (Denmark)

    Andersen, Troels Bak

    by the so-called fusion ideals. The fusion rings of Wess-Zumino-Witten models have been widely studied and are well understood in terms of precise combinatorial descriptions and explicit generating sets of the fusion ideals. They also appear in another, more general, setting via tilting modules for quantum......This dissertation investigates fusion rings, which are Grothendieck groups of rigid, monoidal, semisimple, abelian categories. Special interest is in rational fusion rings, i.e., fusion rings which admit a finite basis, for as commutative rings they may be presented as quotients of polynomial rings...

  14. Idealism and materialism in perception.

    Science.gov (United States)

    Rose, David; Brown, Dora

    2015-01-01

    Koenderink (2014, Perception, 43, 1-6) has said most Perception readers are deluded, because they believe an 'All Seeing Eye' observes an objective reality. We trace the source of Koenderink's assertion to his metaphysical idealism, and point to two major weaknesses in his position-namely, its dualism and foundationalism. We counter with arguments from modern philosophy of science for the existence of an objective material reality, contrast Koenderink's enactivism to his idealism, and point to ways in which phenomenology and cognitive science are complementary and not mutually exclusive.

  15. Effect of lowering blood pressure on cardiovascular events and mortality in patients on dialysis : a systematic review and meta-analysis of randomised controlled trials

    NARCIS (Netherlands)

    Heerspink, HiddoJ Lambers; Ninomiya, Toshiharu; Zoungas, Sophia; de Zeeuw, Dick; Grobbee, Diederick E.; Jardine, Meg J.; Gallagher, Martin; Roberts, Matthew A.; Cass, Alan; Neal, Bruce; Perkovic, Vlado

    2009-01-01

    Background Patients undergoing dialysis have a substantially increased risk of cardiovascular mortality and morbidity. Although several trials have shown the cardiovascular benefits of lowering blood pressure in the general population, there is uncertainty about the efficacy and tolerability of

  16. Lower gastrointestinal malignancies

    International Nuclear Information System (INIS)

    Minsky, Bruce D.

    1995-01-01

    Objective: This refresher course will review the current knowledge as well as ongoing and future research strategies in lower gastrointestinal malignancies. Radiation therapy has a significant role in the adjuvant treatment of lower gastrointestinal malignancies. Furthermore, there are data to suggest that radiation therapy is an integral component of the conservative management (organ preservation) of rectal and anal cancers. 1. Colon cancer. The standard adjuvant treatment for node positive or high risk transmural colon cancer is postoperative 5-FU and Levamisole. There are retrospective data to suggest that certain subsets of high risk patients may benefit from postoperative radiation therapy. 2. Rectal cancer. Randomized trials have revealed an advantage of postoperative radiation therapy plus chemotherapy in transmural and/or node positive rectal cancer. In the adjuvant setting the use of continuous infusion 5-FU may be more beneficial compared with bolus 5-FU. Despite the improvement in survival, postoperative therapies are associated with an approximately 35% incidence of grade 3+ toxicity. Recent data suggest that the use of preoperative combined modality therapy may be associated with less toxicity as well as increase the chance of sphincter preservation. New Intergroup trials addressing these issues will be presented. In patients with locally advanced unresectable rectal cancer, the addition of intraoperative radiation therapy may further improve local control. 3. Anal cancer. The use of combined 5-FU/Mitomycin-C and pelvic radiation therapy is effective in the treatment of anal carcinoma. The RTOG has recently completed a randomized trial addressing the question of the effectiveness and toxicity of Mitomycin-C. The replacement Intergroup Phase III trial will be presented

  17. Lower gastrointestinal malignancies

    International Nuclear Information System (INIS)

    Minsky, Bruce D.

    1996-01-01

    Objective: This refresher course will review the current knowledge as well as ongoing and future research strategies in lower gastrointestinal malignancies. Radiation therapy has a significant role in the adjuvant treatment of lower gastrointestinal malignancies. Furthermore, there are data to suggest that radiation therapy is an integral component of the conservative management (organ preservation) of rectal and anal cancers. 1. Colon cancer. The standard adjuvant treatment for node positive or high risk transmural colon cancer is postoperative 5-FU and Levamisole. There are retrospective data to suggest that certain subsets of high risk patients may benefit from postoperative radiation therapy. 2. Rectal cancer. Randomized trials have revealed an advantage of postoperative radiation therapy plus chemotherapy in transmural and/or node positive rectal cancer. In the adjuvant setting the use of continuous infusion 5-FU may be more beneficial compared with bolus 5-FU. Despite the improvement in survival, postoperative therapies are associated with an approximately 35% incidence of grade 3+ toxicity. Recent data suggest that the use of preoperative combined modality therapy may be associated with less toxicity as well as increase the chance of sphincter preservation. New Intergroup trials addressing these issues will be presented. In patients with locally advanced unresectable rectal cancer, the addition of intraoperative radiation therapy may further improve local control. 3. Anal cancer. The use of combined 5-FU/Mitomycin-C and pelvic radiation therapy is effective in the treatment of anal carcinoma. The RTOG has recently completed a randomized trial addressing the question of the effectiveness and toxicity of Mitomycin-C. The replacement Intergroup Phase III trial will be presented

  18. The ideal male jaw angle--An Internet survey.

    Science.gov (United States)

    Mommaerts, Maurice Y

    2016-04-01

    The ideal male jaw angle has not been established. With the advent of additive manufacturing, precise customized shaping is a reality. This study aimed to define the ideal masculine mandibular angle as an aid for 3-dimensional (3D) design. An Internet survey was conducted using black/white photographs of celebrities and non-celebrities. Preferences regarding gonial angle (profile and frontal views), intergonial width and vertical jaw angle position (face frontal view), and angle curvature and definition in oblique views were obtained using simplified, unbalanced Likert scales. Constructs were defined for planning 3D implant designs. The preferred jaw angle had these characteristics: 130° in face profile view, intergonial width similar to facial width, vertical position in frontal view at the oral commissure or at least not below the lower lip, jawline slope in the face frontal view nearly parallel to (with a maximum 15° downward deviation from) a line extending from the lateral canthus to the alare, ascending ramus slope 65°-75° to the Frankfort horizontal, and curvature in the oblique view visible from earlobe to chin and not pointy. Photogrammetric analysis of panel preferences lead to constructs with values useful for the design of 3D printed jaw angles. Copyright © 2016 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  19. Karakter Ideal Konselor Multibudaya Berdasarkan Nilai Luhur Semar

    Directory of Open Access Journals (Sweden)

    Nora Yuniar Setyaputri

    2017-06-01

    Full Text Available Abstract: Nowadays a lot of counselor labeling their counselee which caused counselor’s lack of multicultural insights. Labeling may have a poor impact on the counselor’s decision in selecting counseling intervention strategies. The multicultural insights of counselors must be enhanced by building an ideal character in themselves. This ideal character is concerned with the understanding and behavior of counselors to respond the condition of heterogeneous counselees and how high the curiosity, interest and motivation of counselors to constantly add multicultural insights that they have. The noble values contained within Semar can be attributed to how the ideal character of multicultural counselors. This study aims to explain the ideal character of multicultural counselor taken from the noble value of Semar as well as linking the character with multicultural competence of counselor. This research uses qualitative approach of library research type. The ideal characteristics of multicultural counselors that can be formulated include: (1 religious; (2 neutral; (3 tolerance; (4 sincere; (5 discipline; (6 social care; (7 friendly; (8 fair; (9 honest; (10 supple; (11 democratic; and (12 curiosity. Abstrak: Saat ini banyak konselor yang melakukan pelabelan karena kurangnya wawasan multibudaya konselor tersebut. Pelabelan yang dilakukan oleh konselor ini dapat berdampak kurang baik terhadap pemilihan strategi intervensi konselor terhadap konselinya. Wawasan multibudaya yang dimiliki konselor harus ditingkatkan dengan cara membangun karakter yang ideal pada diri mereka. Karakter ideal ini berkaitan dengan pemahaman dan perilaku konselor untuk menyikapi kondisi konseli yang heterogen serta seberapa tinggi rasa ingin tahu, minat maupun motivasi konselor untuk senantiasa menambah wawasan multibudaya yang mereka miliki. Nilai-nilai luhur yang terdapat di dalam diri Semar dapat dikaitkan dengan bagaimana karakter ideal konselor multibudaya. Penelitian ini

  20. [Lower is better: ENHANCE affair].

    Science.gov (United States)

    Scardi, Sabino; Umari, Paolo; D'Agata, Bianca Maria

    2008-06-01

    Ezetimibe lowers the intestinal absorption of cholesterol, being complementary to the effects of statin. To check its efficacy in lowering the carotid intima-media thickness, in 2002 a multicenter international trial called ENHANCE was started, in order to assess by ultrasound the regression of atherosclerotic plaques. The protocol tested the use of simvastatin 80 mg + placebo versus simvastatin 80 mg + ezetimibe 10 mg in 720 randomized patients. Both drugs were well tolerated. Combination therapy was associated with a larger reduction in LDL cholesterol, but there were no differences in the intima-media thickness measured at three sites in the carotid arteries, nor differences in cardiovascular events between the two groups in the trial. These results provoked disappointment of sponsors (Merck, Schering Plough) who, although the results of the trial were available since march 2007, delayed official communication of about 18 months. This led to speculations and rumors among media, American Government, cardiologic scientific associations, and consequences in the Ezetimibe market and at Wall Street. In particular, the American College of Cardiology didn't accept the communication of ENHANCE results to the Late Breaking Trial Session of the Chicago congress, diverting it to another secondary forum. In conclusion, the experience of the ENHANCE trial suggests to pharmaceutical companies, researchers, clinicians, scientific companies and media a deep meditation in order to avoid in the future similar problems in the management of results of medical research.

  1. Ideals of ITE students at Glasgow University

    NARCIS (Netherlands)

    de Ruyter, D.J.; Conroy, J.C.; Lappin, M.; McKinney, S.M.

    2003-01-01

    Analysis of a questionnaire completed by initial teacher education (ITE) students at the University of Glasgow shows a clear divergence between their personal and professional ideals. The students define their own ideals predominantly in terms of situations, like being married, having children or

  2. Medical learning curves and the Kantian ideal.

    Science.gov (United States)

    Le Morvan, P; Stock, B

    2005-09-01

    A hitherto unexamined problem for the "Kantian ideal" that one should always treat patients as ends in themselves, and never only as a means to other ends, is explored in this paper. The problem consists of a prima facie conflict between this Kantian ideal and the reality of medical practice. This conflict arises because, at least presently, medical practitioners can only acquire certain skills and abilities by practising on live, human patients, and given the inevitability and ubiquity of learning curves, this learning requires some patients to be treated only as a means to this end. A number of ways of attempting to establish the compatibility of the Kantian Ideal with the reality of medical practice are considered. Each attempt is found to be unsuccessful. Accordingly, until a way is found to reconcile them, we conclude that the Kantian ideal is inconsistent with the reality of medical practice.

  3. Effect of lung-protective ventilation with lower tidal volumes on clinical outcomes among patients undergoing surgery: a meta-analysis of randomized controlled trials.

    Science.gov (United States)

    Gu, Wan-Jie; Wang, Fei; Liu, Jing-Chen

    2015-02-17

    In anesthetized patients undergoing surgery, the role of lung-protective ventilation with lower tidal volumes is unclear. We performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the effect of this ventilation strategy on postoperative outcomes. We searched electronic databases from inception through September 2014. We included RCTs that compared protective ventilation with lower tidal volumes and conventional ventilation with higher tidal volumes in anesthetized adults undergoing surgery. We pooled outcomes using a random-effects model. The primary outcome measures were lung injury and pulmonary infection. We included 19 trials (n=1348). Compared with patients in the control group, those who received lung-protective ventilation had a decreased risk of lung injury (risk ratio [RR] 0.36, 95% confidence interval [CI] 0.17 to 0.78; I2=0%) and pulmonary infection (RR 0.46, 95% CI 0.26 to 0.83; I2=8%), and higher levels of arterial partial pressure of carbon dioxide (standardized mean difference 0.47, 95% CI 0.18 to 0.75; I2=65%). No significant differences were observed between the patient groups in atelectasis, mortality, length of hospital stay, length of stay in the intensive care unit or the ratio of arterial partial pressure of oxygen to fraction of inspired oxygen. Anesthetized patients who received ventilation with lower tidal volumes during surgery had a lower risk of lung injury and pulmonary infection than those given conventional ventilation with higher tidal volumes. Implementation of a lung-protective ventilation strategy with lower tidal volumes may lower the incidence of these outcomes. © 2015 Canadian Medical Association or its licensors.

  4. Ideal related K-theory with coefficients

    DEFF Research Database (Denmark)

    Eilers, Soren; Restorff, Gunnar; Ruiz, Efren

    2017-01-01

    In this paper, we define an invariant, which we believe should be the substitute for total K-theory in the case when there is one distinguished ideal. Moreover, some diagrams relating the new groups to the ordinary K-groups with coefficients are constructed. These diagrams will in most cases help...... to determine the new groups, and will in a companion paper be used to prove a universal multi-coefficient theorem for the one distinguished ideal case for a large class of algebras......In this paper, we define an invariant, which we believe should be the substitute for total K-theory in the case when there is one distinguished ideal. Moreover, some diagrams relating the new groups to the ordinary K-groups with coefficients are constructed. These diagrams will in most cases help...

  5. Clinical Trials

    Medline Plus

    Full Text Available ... benefits of lowering high blood pressure in the elderly outweighed the risks. Other examples of clinical trials ... child to enroll. Also, children aged 7 and older often must agree (assent) to ... as clinical trials for adults. For more information, go to "How Do Clinical ...

  6. [The style of leadership idealized by nurses].

    Science.gov (United States)

    Higa, Elza de Fátima Ribeiro; Trevizan, Maria Auxiliadora

    2005-01-01

    This study focuses on nursing leadership on the basis of Grid theories. According to the authors, these theories are an alternative that allows for leadership development in nursing. The research aimed to identify and analyze the style of leadership idealized by nurses, according to their own view, and to compare the styles of leadership idealized by nurses between the two research institutions. Study subjects were 13 nurses. The results show that nurses at both institutions equally mention they idealize style 9.9, followed by 5.5 and 1.9, with a tendency to reject styles 9.1 and 1.1.

  7. Perumusan Model Moneter Berdasarkan Perilaku Gas Ideal

    Directory of Open Access Journals (Sweden)

    Rachmad Resmiyanto

    2014-04-01

    Full Text Available Telah disusun sebuah model moneter yang berdasarkan perilaku gas ideal. Model disusun dengan menggunakan metode kias/analogi. Model moneter gas ideal mengiaskan jumlah uang beredar dengan volume gas, daya beli dengan tekanan gas dan produksi barang dengan suhu gas. Model ini memiliki formulasi yang berbeda dengan Teori Kuantitas Uang (Quantity Theory of Money yang dicetuskan oleh Irving Fisher, model moneter Marshal-Pigou dari Cambridge serta model moneter ala Keynes. Selama ini 3 model tersebut dianggap sebagai model yang mapan dalam teori moneter pada buku-buku teks ekonomi. Model moneter gas ideal dapat menjadi cara pandang baru terhadap sistem moneter.

  8. Surface dependency in thermodynamics of ideal gases

    International Nuclear Information System (INIS)

    Sisman, Altug

    2004-01-01

    The Casimir-like size effect rises in ideal gases confined in a finite domain due to the wave character of atoms. By considering this effect, thermodynamic properties of an ideal gas confined in spherical and cylindrical geometries are derived and compared with those in rectangular geometry. It is seen that an ideal gas exhibits an unavoidable quantum surface free energy and surface over volume ratio becomes a control variable on thermodynamic state functions in microscale. Thermodynamics turns into non-extensive thermodynamics and geometry difference becomes a driving force since the surface over volume ratio depends on the geometry

  9. Ideals as Anchors for Relationship Experiences

    OpenAIRE

    Frye, Margaret; Trinitapoli, Jenny

    2015-01-01

    Research on young-adult sexuality in sub-Saharan Africa typically conceptualizes sex as an individual-level risk behavior. We introduce a new approach that connects the conditions surrounding the initiation of sex with subsequent relationship well-being, examines relationships as sequences of interdependent events, and indexes relationship experiences to individually held ideals. New card-sort data from southern Malawi capture young women’s relationship experiences and their ideals in a seque...

  10. The Idealized Cultural Encounter

    DEFF Research Database (Denmark)

    Christiansen, Lene Bull

    Studies into cultural encounters have predominantly taken point of departure in ‘problematic encounters’, in which researchers and participants see cultural difference as an obstacle on the road to harmonious relationships (e.g. in ‘the clash of civilisations,’ or in migration/integration studies......). This paper proposes to study cultural encounters which are organised around ideals of cultural difference as a positive social and political force. The Danish People to People NGO Mellemfolkeligt Samvirke (MS) is build around ideals of equality, co-operation, mutuality and solidarity between people...... and cultures. A prominent feature of the organisation is organised cultural encounters between Northern (predominantly Danish) volunteers and Africans, which takes place at ‘training centres’ both in Denmark and in African countries, such as Kenya or Tanzania. In this paper I will outline the theoretical...

  11. Ideal and Nonideal Reasoning in Educational Theory

    Science.gov (United States)

    Jaggar, Alison M.

    2015-01-01

    The terms "ideal theory" and "nonideal theory" are used in contemporary Anglophone political philosophy to identify alternative methodological approaches for justifying normative claims. Each term is used in multiple ways. In this article Alison M. Jaggar disentangles several versions of ideal and nonideal theory with a view to…

  12. IN SEARCH OF IDEAL FORM- RATIO OF TRIANGULAR CHANNEL

    Directory of Open Access Journals (Sweden)

    B. C. DAS

    2014-11-01

    Full Text Available In Search of Ideal Form-Ratio of Triangular Channel. Cross-sectional form of a natural channel is a two dimensional variable which is thoroughly studied by scholars from different fields on natural sciences like hydrology, geology, geomorphology, etc. Average river channels tend to develop their channel-cross sectional form in a way to produce an approximate equilibrium between the channel and the water and sediment it transport. But how far it is deviated from the ideal cross-sectional form can only be determined by knowing the ideal form which was calculated by Hickin for rectangular channel. This ideal cross-sectional form of ‘maximum efficiency’ is virtually a theoretical one and attaining of which the river transports its water and load with least friction with its bed. ‘Ideal form ratio’ provides numerical tools for triangular channel to determine the degree of deviation of a cross-sectional form from that of an ideal one.

  13. Idealized cultural beliefs about gender: implications for mental health.

    Science.gov (United States)

    Mahalingam, Ramaswami; Jackson, Benita

    2007-12-01

    In this paper, we examined the relationship between culture-specific ideals (chastity, masculinity, caste beliefs) and self-esteem, shame and depression using an idealized cultural model proposed by Mahalingam (2006, In: Mahalingam R (ed) Cultural psychology of immigrants. Lawrence Erlbaum, Mahwah, NJ, pp 1-14). Participants were from communities with a history of extreme male-biased sex ratios in Tamilnadu, India (N = 785). We hypothesized a dual-process model of self-appraisals suggesting that achieving idealized cultural identities would increase both self-esteem and shame, with the latter leading to depression, even after controlling for key covariates. We tested this using structural equation modeling. The proposed idealized cultural identities model had an excellent fit (CFI = 0.99); the effect of idealized identities on self-esteem, shame and depression differed by gender. Idealized beliefs about gender relate to psychological well-being in gender specific ways in extreme son preference communities. We discuss implications of these findings for future research and community-based interventions.

  14. Efficacy of sacubitril/valsartan vs. enalapril at lower than target doses in heart failure with reduced ejection fraction: the PARADIGM-HF trial.

    Science.gov (United States)

    Vardeny, Orly; Claggett, Brian; Packer, Milton; Zile, Michael R; Rouleau, Jean; Swedberg, Karl; Teerlink, John R; Desai, Akshay S; Lefkowitz, Martin; Shi, Victor; McMurray, John J V; Solomon, Scott D

    2016-10-01

    In this analysis, we utilized data from PARADIGM-HF to test the hypothesis that participants who exhibited any dose reduction during the trial would have similar benefits from lower doses of sacubitril/valsartan relative to lower doses of enalapril. In a post-hoc analysis from PARADIGM-HF, we characterized patients by whether they received the maximal dose (200 mg sacubitril/valsartan or 10 mg enalapril twice daily) throughout the trial or had any dose reduction to lower doses (100/50/0 mg sacubitril/valsartan or 5/2.5/0 mg enalapril twice daily). The treatment effect for the primary outcome was estimated, stratified by dose level using time-updated Cox regression models. In the two treatment arms, participants with a dose reduction (43% of those randomized to enalapril and 42% of those randomized to sacubitril/valsartan) had similar baseline characteristics and similar baseline predictors of the need for dose reduction. In a time-updated analysis, any dose reduction was associated with a higher subsequent risk of the primary event [hazard ratio (HR) 2.5, 95% confidence interval (CI) 2.2-2.7]. However, the treatment benefit of sacubitril/valsartan over enalapril following a dose reduction was similar (HR 0.80, 95% CI 0.70-0.93, P sacubitril/valsartan relative to those on lower doses of enalapril was similar to that of patients who remained on target doses of both drugs. © 2016 The Authors. European Journal of Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.

  15. Truncated Groebner fans and lattice ideals

    OpenAIRE

    Lauritzen, Niels

    2005-01-01

    We outline a generalization of the Groebner fan of a homogeneous ideal with maximal cells parametrizing truncated Groebner bases. This "truncated" Groebner fan is usually much smaller than the full Groebner fan and offers the natural framework for conversion between truncated Groebner bases. The generic Groebner walk generalizes naturally to this setting by using the Buchberger algorithm with truncation on facets. We specialize to the setting of lattice ideals. Here facets along the generic w...

  16. Body size ideals and dissatisfaction in Ghanaian adolescents: role of media, lifestyle and well-being.

    Science.gov (United States)

    Michels, N; Amenyah, S D

    2017-05-01

    To inspire effective health promotion campaigns, we tested the relationship of ideal body size and body size dissatisfaction with (1) the potential resulting health-influencing factors diet, physical activity and well-being; and (2) with media as a potential influencer of body ideals. This is a cross-sectional study in 370 Ghanaian adolescents (aged 11-18 years). Questionnaires included disordered eating (EAT26), diet quality (FFQ), physical activity (IPAQ), well-being (KINDL) and media influence on appearance (SATAQ: pressure, internalisation and information). Ideal body size and body size dissatisfaction were assessed using the Stunkard figure rating scale. Body mass index (BMI), skinfolds and waist were measured. Linear regressions were adjusted for gender, age and parental education. Also, mediation was tested: 'can perceived media influence play a role in the effects of actual body size on body size dissatisfaction?'. Body size dissatisfaction was associated with lower well-being and more media influence (pressure and internalisation) but not with physical activity, diet quality or disordered eating. An underweight body size ideal might worsen disordered eating but was not significantly related to the other predictors of interest. Only a partial mediation effect by media pressure was found: especially overweight adolescents felt media pressure, and this media pressure was associated with more body size dissatisfaction. To prevent disordered eating and low well-being, health messages should include strategies that reduce body size dissatisfaction and increase body esteem by not focussing on the thin body ideal. Changing body size ideals in the media might be an appropriate way since media pressure was a mediator in the BMI-dissatisfaction relation. Copyright © 2017 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  17. Local thermal equilibrium and ideal gas Stephani universes

    OpenAIRE

    Coll, Bartolomé; Ferrando, Joan Josep

    2004-01-01

    The Stephani universes that can be interpreted as an ideal gas evolving in local thermal equilibrium are determined. Five classes of thermodynamic schemes are admissible, which give rise to five classes of regular models and three classes of singular models. No Stephani universes exist representing an exact solution to a classical ideal gas (one for which the internal energy is proportional to the temperature). But some Stephani universes may approximate a classical ideal gas at first order i...

  18. Measurable Control System Security through Ideal Driven Technical Metrics

    Energy Technology Data Exchange (ETDEWEB)

    Miles McQueen; Wayne Boyer; Sean McBride; Marie Farrar; Zachary Tudor

    2008-01-01

    The Department of Homeland Security National Cyber Security Division supported development of a small set of security ideals as a framework to establish measurable control systems security. Based on these ideals, a draft set of proposed technical metrics was developed to allow control systems owner-operators to track improvements or degradations in their individual control systems security posture. The technical metrics development effort included review and evaluation of over thirty metrics-related documents. On the bases of complexity, ambiguity, or misleading and distorting effects the metrics identified during the reviews were determined to be weaker than necessary to aid defense against the myriad threats posed by cyber-terrorism to human safety, as well as to economic prosperity. Using the results of our metrics review and the set of security ideals as a starting point for metrics development, we identified thirteen potential technical metrics - with at least one metric supporting each ideal. Two case study applications of the ideals and thirteen metrics to control systems were then performed to establish potential difficulties in applying both the ideals and the metrics. The case studies resulted in no changes to the ideals, and only a few deletions and refinements to the thirteen potential metrics. This led to a final proposed set of ten core technical metrics. To further validate the security ideals, the modifications made to the original thirteen potential metrics, and the final proposed set of ten core metrics, seven separate control systems security assessments performed over the past three years were reviewed for findings and recommended mitigations. These findings and mitigations were then mapped to the security ideals and metrics to assess gaps in their coverage. The mappings indicated that there are no gaps in the security ideals and that the ten core technical metrics provide significant coverage of standard security issues with 87% coverage. Based

  19. Tensor norms and operator ideals

    CERN Document Server

    Defant, A; Floret, K

    1992-01-01

    The three chapters of this book are entitled Basic Concepts, Tensor Norms, and Special Topics. The first may serve as part of an introductory course in Functional Analysis since it shows the powerful use of the projective and injective tensor norms, as well as the basics of the theory of operator ideals. The second chapter is the main part of the book: it presents the theory of tensor norms as designed by Grothendieck in the Resumé and deals with the relation between tensor norms and operator ideals. The last chapter deals with special questions. Each section is accompanied by a series of exer

  20. Promoting Spiritual Ideals through Design Thinking in Public Schools

    Science.gov (United States)

    Tan, Charlene; Wong, Yew-Leong

    2012-01-01

    Against a backdrop of the debates on religious education in public or state schools, we argue for the introduction of "spiritual ideals" into the public school curriculum. We distinguish our notion of spiritual ideals from "religious ideals" as conceptualised by De Ruyter and Merry. While we agree with De Ruyter and Merry that…

  1. IDEAL-CRT: A Phase 1/2 Trial of Isotoxic Dose-Escalated Radiation Therapy and Concurrent Chemotherapy in Patients With Stage II/III Non-Small Cell Lung Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Landau, David B., E-mail: david.landau@kcl.ac.uk [Guy' s & St. Thomas' NHS Trust, King' s College London, London (United Kingdom); Hughes, Laura [Cancer Research UK and UCL Cancer Trials Centre, London (United Kingdom); Baker, Angela [Clatterbridge Cancer Centre, Bebington (United Kingdom); Bates, Andrew T. [Southampton General Hospital, Southampton (United Kingdom); Bayne, Michael C. [Poole Hospital, Poole (United Kingdom); Counsell, Nicholas [Cancer Research UK and UCL Cancer Trials Centre, London (United Kingdom); Garcia-Alonso, Angel [North Wales Cancer Centre, Rhyl (United Kingdom); Harden, Susan V. [Addenbrookes Hospital, Cambridge (United Kingdom); Hicks, Jonathan D. [Beatson West of Scotland Cancer Centre, Glasgow (United Kingdom); Hughes, Simon R. [Guy' s & St. Thomas' NHS Trust, King' s College London, London (United Kingdom); Illsley, Marianne C. [Royal Surrey County Hospital, Guilford (United Kingdom); Khan, Iftekhar [Cancer Research UK and UCL Cancer Trials Centre, London (United Kingdom); Laurence, Virginia [Poole Hospital, Poole (United Kingdom); Malik, Zafar; Mayles, Helen; Mayles, William Philip M. [Clatterbridge Cancer Centre, Bebington (United Kingdom); Miles, Elizabeth [Mount Vernon Hospital, Middlesex (United Kingdom); Mohammed, Nazia [Beatson West of Scotland Cancer Centre, Glasgow (United Kingdom); Ngai, Yenting [Cancer Research UK and UCL Cancer Trials Centre, London (United Kingdom); Parsons, Emma [Mount Vernon Hospital, Middlesex (United Kingdom); and others

    2016-08-01

    Purpose: To report toxicity and early survival data for IDEAL-CRT, a trial of dose-escalated concurrent chemoradiotherapy (CRT) for non-small cell lung cancer. Patients and Methods: Patients received tumor doses of 63 to 73 Gy in 30 once-daily fractions over 6 weeks with 2 concurrent cycles of cisplatin and vinorelbine. They were assigned to 1 of 2 groups according to esophageal dose. In group 1, tumor doses were determined by an experimental constraint on maximum esophageal dose, which was escalated following a 6 + 6 design from 65 Gy through 68 Gy to 71 Gy, allowing an esophageal maximum tolerated dose to be determined from early and late toxicities. Tumor doses for group 2 patients were determined by other tissue constraints, often lung. Overall survival, progression-free survival, tumor response, and toxicity were evaluated for both groups combined. Results: Eight centers recruited 84 patients: 13, 12, and 10, respectively, in the 65-Gy, 68-Gy, and 71-Gy cohorts of group 1; and 49 in group 2. The mean prescribed tumor dose was 67.7 Gy. Five grade 3 esophagitis and 3 grade 3 pneumonitis events were observed across both groups. After 1 fatal esophageal perforation in the 71-Gy cohort, 68 Gy was declared the esophageal maximum tolerated dose. With a median follow-up of 35 months, median overall survival was 36.9 months, and overall survival and progression-free survival were 87.8% and 72.0%, respectively, at 1 year and 68.0% and 48.5% at 2 years. Conclusions: IDEAL-CRT achieved significant treatment intensification with acceptable toxicity and promising survival. The isotoxic design allowed the esophageal maximum tolerated dose to be identified from relatively few patients.

  2. Ideal Convergence of k-Positive Linear Operators

    Directory of Open Access Journals (Sweden)

    Akif Gadjiev

    2012-01-01

    Full Text Available We study some ideal convergence results of k-positive linear operators defined on an appropriate subspace of the space of all analytic functions on a bounded simply connected domain in the complex plane. We also show that our approximation results with respect to ideal convergence are more general than the classical ones.

  3. Relationship Between Ideal Cardiovascular Health and Disability in Older Adults: The Chilean National Health Survey (2009-10).

    Science.gov (United States)

    García-Hermoso, Antonio; Ramírez-Vélez, Robinson; Ramirez-Campillo, Rodrigo; Izquierdo, Mikel

    2017-12-01

    This study aimed to examine the relationship between disability and the American Heart Association metric of ideal cardiovascular health (CVH) in older adults from the 2009-10 Chilean National Health Survey. Data from 460 older adults were analyzed. All subjects were interviewed using the standardized World Health Survey, which includes 16 health-related questions and assesses the domains of mobility, self-care, pain and discomfort, cognition, interpersonal activities, vision, sleep and energy, and affect. A person who responds with a difficulty rating of severe, extreme, or unable to do in at least one of these eight functioning domains is considered to have a disability. Ideal CVH was defined as meeting the ideal levels of four behaviors (smoking, body mass index, physical activity, diet adherence) and three factors (total cholesterol, fasting glucose, blood pressure). Logistic regression analysis suggested that ideal physical activity reduces the odds of disability (odds ratio (OR) = 0.55, 95% confidence interval (CI) = 0.36-0.85). Moreover, participants with intermediate (3-4 metrics) (OR = 0.63, 95% CI = 0.41-0.97) and ideal (5-7 metrics) (OR = 0.51, 95% CI = 0.24-0.97) CVH profiles had lower odds of disability independent of history of vascular events and arthritis disease than those with a poor profile (0-2 metrics). In conclusion, despite the cross-sectional design, this study suggests the importance of promoting ideal CVH because of their relationship with disability. © 2017, Copyright the Authors Journal compilation © 2017, The American Geriatrics Society.

  4. An Ideal Gas Law Simulator for Atmospheric Gas Molecules ...

    African Journals Online (AJOL)

    The ideal gas law which is the equation of state of a hypothetical ideal gas that allows us to gain useful insights into the behavior of most real gases at low densities was utilized in this work to conceptualize, design and develop the ideal gas law simulator in a 3 dimensional space using Microsoft Visual Studio, Microsoft ...

  5. Clinical efficacy and prognostic indicators for lower limb pedalling exercise early after stroke: Study protocol for a pilot randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Myint Phyo

    2011-03-01

    Full Text Available Abstract Background It is known that repetitive, skilled, functional movement is beneficial in driving functional reorganisation of the brain early after stroke. This study will investigate a whether pedalling an upright, static exercise cycle, to provide such beneficial activity, will enhance recovery and b which stroke survivors might be able to participate in pedalling. Methods/Design Participants (n = 24 will be up to 30 days since stroke onset, with unilateral weakness and unable to walk without assistance. This study will use a modified exercise bicycle fitted with a UniCam crank. All participants will give informed consent, then undergo baseline measurements, and then attempt to pedal. Those able to pedal will be entered into a single-centre, observer-blinded randomised controlled trial (RCT. All participants will receive routine rehabilitation. The experimental group will, in addition, pedal daily for up to ten minutes, for up to ten working days. Prognostic indicators, measured at baseline, will be: site of stroke lesion, trunk control, ability to ambulate, and severity of lower limb paresis. The primary outcome for the RCT is ability to voluntarily contract paretic lower limb muscle, measured by the Motricity Index. Secondary outcomes include ability to ambulate and timing of onset and offset of activity in antagonist muscle groups during pedalling, measured by EMG. Discussion This protocol is for a trial of a novel therapy intervention. Findings will establish whether there is sufficient evidence of benefit to justify proceeding with further research into clinical efficacy of upright pedalling exercise early after stroke. Information on potential prognostic indicators will suggest which stroke survivors could benefit from the intervention. Trial Registration ISRCTN: ISRCTN45392701

  6. The cyclicity of a cubic system with nonradical Bautin ideal

    Science.gov (United States)

    Levandovskyy, Viktor; Romanovski, Valery G.; Shafer, Douglas S.

    We present a method for investigating the cyclicity of an elementary focus or center of a polynomial system of differential equations by means of complexification of the system and application of algorithms of computational algebra, showing an approach to treating the case that the Bautin ideal B of focus quantities is not a radical ideal (more precisely, when the ideal B is not radical, where B is the ideal generated by the shortest initial string of focus quantities that, like the Bautin ideal, determines the center variety). We illustrate the method with a family of cubic systems.

  7. Coupling and absorption of lower-hybrid waves in a thermonuclear plasma

    International Nuclear Information System (INIS)

    Puri, S.; Tutter, M.

    1975-01-01

    The three important aspects, namely 1) accessibility, 2) matching and 3) absorption of the lower-hybrid waves in a thermonuclear plasma are studied under idealized but physically pertinent conditions within the framework of linearized theory. (orig.) [de

  8. Idealization of the analyst by the young adult.

    Science.gov (United States)

    Chused, J F

    1987-01-01

    Idealization is an intrapsychic process that serves many functions. In addition to its use defensively and for gratification of libidinal and aggressive drive derivatives, it can contribute to developmental progression, particularly during late adolescence and young adulthood. During an analysis, it is important to recognize all the determinants of idealization, including those related to the reworking of developmental conflicts. If an analyst understands idealization solely as a manifestation of pathology, he may interfere with his patient's use of it for the development of autonomous functioning.

  9. Positive Implicative Ideals of BCK-Algebras Based on Intersectional Soft Sets

    Directory of Open Access Journals (Sweden)

    Eun Hwan Roh

    2013-01-01

    Full Text Available The aim of this paper is to lay a foundation for providing a soft algebraic tool in considering many problems that contain uncertainties. In order to provide these soft algebraic structures, the notion of int-soft positive implicative ideals is introduced, and related properties are investigated. Relations between an int-soft ideal and an int-soft positive implicative ideal are established. Characterizations of an int-soft positive implicative ideal are obtained. Extension property for an int-soft positive implicative ideal is constructed. The ∧-product and ∨-product of int-soft positive implicative ideals are considered, and the soft intersection (resp., union of int-soft positive implicative ideals is discussed.

  10. 40 CFR 1065.645 - Amount of water in an ideal gas.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Amount of water in an ideal gas. 1065... in an ideal gas. This section describes how to determine the amount of water in an ideal gas, which... of water in an ideal gas, x H20, as follows: ER30AP10.034 Where: x H20 = amount of water in an ideal...

  11. On the ideal gas of tachyons

    International Nuclear Information System (INIS)

    Mrowczynski, S.

    1983-01-01

    The properties of the ideal gas of classical (nonquantum) faster than light particles-tachyons have been considered. The basic notions of thermodynamics of tachyons have been introduced. We have found the partition function and other thermodynamical quantities for the ideal tachyon gas. The equation of state which we have found for tachyons is exactly the same as for the ideal gas of partictes slower than light-bradyons. The internal energy and the apecific heat have been discussed at low and at very high temperatures. It has been shown that in high temperature limit the properties of gas of tachyons and gas of bradyons are th'e same. The numerical calculations concerning the internal energy and specific heat at different temperatures were performed and the results have been presented. It has been shown that in full interval of temperature the characteristics of gas of tachyons are similar to those of gas of bradyons

  12. On Bipolar Valued Fuzzy k-Ideals in Hermirings

    International Nuclear Information System (INIS)

    Mahmood, T.; Ejaz, A.

    2015-01-01

    In this paper we discuss some results associated with bipolar valued fuzzy k -ideals of hermirings. We also define bipolar valued fuzzy k-intrinsic product and characterize k-hemiregular hermirings by using their bipolar valued fuzzy k -ideals. (author)

  13. On the union of graded prime ideals

    Directory of Open Access Journals (Sweden)

    Uregen Rabia Nagehan

    2016-01-01

    Full Text Available In this paper we investigate graded compactly packed rings, which is defined as; if any graded ideal I of R is contained in the union of a family of graded prime ideals of R, then I is actually contained in one of the graded prime ideals of the family. We give some characterizations of graded compactly packed rings. Further, we examine this property on h – Spec(R. We also define a generalization of graded compactly packed rings, the graded coprimely packed rings. We show that R is a graded compactly packed ring if and only if R is a graded coprimely packed ring whenever R be a graded integral domain and h – dim R = 1.

  14. Beyond ideal speech situations: adapting to communication asymmetries in health care.

    Science.gov (United States)

    Gillespie, Alex; Reader, Tom; Cornish, Flora; Campbell, Catherine

    2014-01-01

    Inclusive, unconstrained and honest communication is widely advocated as beneficial and ethical. We critically explore this assumption by reflecting upon our research in acute care, informal care and public health. Using Habermas' ideals of dialogue to conceptualise ideal speech, we concur with observations that health care is often characterised by intractable exclusions and constraints. Rather than advocating implementing the ideals of dialogue, however, we examine how people adapt to these difficult and intransigent contexts. Non-ideal contexts, we find, sometimes call for non-ideal responses. Deception and furthering personal interests, and thus departing from the ideals of dialogue, can be adaptive responses.

  15. Susceptibility for thin ideal media and eating styles

    NARCIS (Netherlands)

    Anschutz, Doeschka J; Engels, Rutger C M E; van Strien, Tatjana

    This study examined the relations between susceptibility for thin ideal media and restrained, emotional and external eating, directly and indirectly through body dissatisfaction. Thin ideal media susceptibility, body dissatisfaction and eating styles were measured in a sample of 163 female students.

  16. Self-Esteem, Social Support, Collectivism, and the Thin-Ideal in Latina College Undergraduates

    Science.gov (United States)

    Cordero, Elizabeth D.

    2010-01-01

    Thin-ideal internalization (TII) reflects agreement that thinness equates with beauty. TII is a risk factor for body dissatisfaction and eating pathology; this phenomenon and its correlates, however, are just beginning to be studied in Latina undergraduates. This study examined the ability of self-esteem, social support, and collectivism to predict TII in Latina undergraduates. It was hypothesized that higher levels of self-esteem, social support, and collectivism would predict lower levels of TII. Cross-sectional data were analyzed using multiple regression; the model was significant, p < .01. Although both self-esteem and social support negatively correlated with thin-ideal internalization, only self-esteem accounted for a significant amount of variance. Results indicate that investigations of self-esteem as a protective factor against TII in Latina undergraduates would be fruitful, as would how self-esteem and social support affect the relationship between TII and other variables. Implications and limitations are discussed. PMID:21147052

  17. Physical activity and trial-by-trial adjustments of response conflict.

    Science.gov (United States)

    Kamijo, Keita; Takeda, Yuji

    2013-08-01

    The relationship of physical activity to trial-by-trial adjustments of response conflict was assessed using behavioral task performance, the N2 event-related brain potential component, and phase-locking values (PLVs) in a lower gamma band during a perceptual conflict task. Nineteen physically active and 19 inactive young adults (mean age = 21.3 years) performed a Navon task, using a global letter made up of local letters of either the same kind (congruent trials) or a different kind (incongruent trials). Findings revealed that active individuals exhibited smaller N2 amplitudes and greater PLVs on incongruent trials that were preceded by incongruent trials compared with those preceded by congruent trials. Such phenomena were not observed for inactive individuals. These results suggest that greater physical activity is associated with larger trial-by-trial adjustments of response conflict, which we attribute to upregulation of top-down cognitive control and reductions in response conflict.

  18. From heaven to earth. A comparison of ideals of ITE students

    NARCIS (Netherlands)

    de Ruyter, D.J.; Conroy, J.C.; Lappin, M.; McKinney, S.M.

    2003-01-01

    This article describes and discusses the outcomes of an open-ended questionnaire completed by Initial Teacher Education (ITE) students about their personal and professional ideals, that is, ideals they would like to pass on to their pupils, their ideal teacher and ideal school. We compared five

  19. Ideal magnetohydrodynamic stability of axisymmetric mirrors

    International Nuclear Information System (INIS)

    D'Ippolito, D.A.; Hafizi, B.; Myra, J.R.

    1982-01-01

    The governing partial differential equation for general mode-number pressure-driven ballooning modes in a long-thin, axisymmetric plasma is derived within the context of ideal magnetohydrodynamics. It is shown that the equation reduces in special limits to the Hain--Luest equation, the high-m diffuse p(psi) ballooning equation, and the low-m sharp-boundary equation. A low-β analytic solution of the full partial differential equation is presented for quasiflute modes in an idealized tandem mirror model to elucidate the relationship of the various limiting cases

  20. Non-splitting in Kirchberg's Ideal-related KK-Theory

    DEFF Research Database (Denmark)

    Eilers, Søren; Restorff, Gunnar; Ruiz, Efren

    2011-01-01

    A. Bonkat obtained a universal coefficient theorem in the setting of Kirchberg's ideal-related KK-theory in the fundamental case of a C*-algebra with one specified ideal. The universal coefficient sequence was shown to split, unnaturally, under certain conditions. Employing certain K-theoretical ...

  1. Brain activation upon ideal-body media exposure and peer feedback in late adolescent girls.

    Science.gov (United States)

    van der Meulen, Mara; Veldhuis, Jolanda; Braams, Barbara R; Peters, Sabine; Konijn, Elly A; Crone, Eveline A

    2017-08-01

    Media's prevailing thin-body ideal plays a vital role in adolescent girls' body image development, but the co-occurring impact of peer feedback is understudied. The present study used functional magnetic resonance imaging (fMRI) to test media imagery and peer feedback combinations on neural activity related to thin-body ideals. Twenty-four healthy female late adolescents rated precategorized body sizes of bikini models (too thin or normal), directly followed by ostensible peer feedback (too thin or normal). Consistent with prior studies on social feedback processing, results showed increased brain activity in the dorsal medial prefrontal cortex (dmPFC)/anterior cingulate cortex (ACC) and bilateral insula in incongruent situations: when participants rated media models' body size as normal while peer feedback indicated the models as too thin (or vice versa). This effect was stronger for girls with lower self-esteem. A subsequent behavioral study (N = 34 female late adolescents, separate sample) demonstrated that participants changed behavior in the direction of the peer feedback: precategorized normal sized models were rated as too thin more often after receiving too thin peer feedback. This suggests that the neural responses upon peer feedback may influence subsequent choice. Our results show that media-by-peer interactions have pronounced effects on girls' body ideals.

  2. Media-portrayed idealized images, body shame, and appearance anxiety.

    Science.gov (United States)

    Monro, Fiona; Huon, Gail

    2005-07-01

    This study was designed to determine the effects of media-portrayed idealized images on young women's body shame and appearance anxiety, and to establish whether the effects depend on advertisement type and on participant self-objectification. Participants were 39 female university students. Twenty-four magazine advertisements comprised 12 body-related and 12 non-body-related products, one half of each with, and the other one half without, idealized images. Preexposure and post exposure body shame and appearance anxiety measures were recorded. Appearance anxiety increased after viewing advertisements featuring idealized images. There was also a significant interaction between self-objectification level and idealized body (presence vs. absence). No differences emerged for body-related compared with non-body-related product advertisements. The only result for body shame was a main effect for time. Participants' body shame increased after exposure to idealized images, irrespective of advertisement type. Although our findings reveal that media-portrayed idealized images detrimentally affect the body image of young women, they highlight the individual differences in vulnerability and the different effects for different components of body image. These results are discussed in terms of their implications for the prevention and early intervention of body image and dieting-related disorders. ( Copyright 2005 by Wiley Periodicals, Inc

  3. Group graded associated ideals with flat base change of rings and ...

    Indian Academy of Sciences (India)

    developed in [12] for G-associated ideals, that is, the behaviour of G-associated ideals. (AssG) with short exact sequences. Second, in §4 we consider the generalized notions of. G-associated prime ideals for not necessarily Noetherian rings and introduce strong Krull. G-associated ideals (AssSG) with flat base change of ...

  4. Neuromuscular training reduces lower limb injuries in elite female basketball players. A cluster randomized controlled trial.

    Science.gov (United States)

    Bonato, M; Benis, R; La Torre, A

    2018-04-01

    The study was a two-armed, parallel group, cluster randomized controlled trial in which 15 teams (160 players) were assigned to either an experimental group (EG, 8 teams n = 86), which warmed-up with bodyweight neuromuscular exercises, or a control group (CG, 7 teams, n = 74) that performed standard tactical-technical exercises before training. All injuries during the 2015-2016 regular season were counted. Epidemiologic incidence proportion and incidence rate were also calculated. Countermovement jump (CMJ) and composite Y-Excursion Balance test (YBT) were used to assess lower limb strength and postural control. A total of 111 injuries were recorded. Chi-square test detected statistically significant differences between EG and CG (32 vs 79, P = .006). Significant differences in the injuries sustained in the EG (21 vs 11, P = .024) and CG (52 vs 27, P = .0001) during training and matches, respectively, were observed. Significant differences in post-intervention injuries were observed between in EG and CG during training (21 vs 52, P training into warm-up routines reduced the incidence of serious lower limb injuries in elite female basketball players. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. Coupling Ideality of Integrated Planar High-Q Microresonators

    Science.gov (United States)

    Pfeiffer, Martin H. P.; Liu, Junqiu; Geiselmann, Michael; Kippenberg, Tobias J.

    2017-02-01

    Chip-scale optical microresonators with integrated planar optical waveguides are useful building blocks for linear, nonlinear, and quantum-optical photonic devices alike. Loss reduction through improving fabrication processes results in several integrated microresonator platforms attaining quality (Q ) factors of several millions. Beyond the improvement of the quality factor, the ability to operate the microresonator with high coupling ideality in the overcoupled regime is of central importance. In this regime, the dominant source of loss constitutes the coupling to a single desired output channel, which is particularly important not only for quantum-optical applications such as the generation of squeezed light and correlated photon pairs but also for linear and nonlinear photonics. However, to date, the coupling ideality in integrated photonic microresonators is not well understood, in particular, design-dependent losses and their impact on the regime of high ideality. Here we investigate design-dependent parasitic losses described by the coupling ideality of the commonly employed microresonator design consisting of a microring-resonator waveguide side coupled to a straight bus waveguide, a system which is not properly described by the conventional input-output theory of open systems due to the presence of higher-order modes. By systematic characterization of multimode high-Q silicon nitride microresonator devices, we show that this design can suffer from low coupling ideality. By performing 3D simulations, we identify the coupling to higher-order bus waveguide modes as the dominant origin of parasitic losses which lead to the low coupling ideality. Using suitably designed bus waveguides, parasitic losses are mitigated with a nearly unity ideality and strong overcoupling (i.e., a ratio of external coupling to internal resonator loss rate >9 ) are demonstrated. Moreover, we find that different resonator modes can exchange power through the coupler, which, therefore

  6. Exercise for lower limb osteoarthritis: systematic review incorporating trial sequential analysis and network meta-analysis.

    Science.gov (United States)

    Uthman, Olalekan A; van der Windt, Danielle A; Jordan, Joanne L; Dziedzic, Krysia S; Healey, Emma L; Peat, George M; Foster, Nadine E

    2014-11-01

    Which types of exercise intervention are most effective in relieving pain and improving function in people with lower limb osteoarthritis? As of 2002 sufficient evidence had accumulated to show significant benefit of exercise over no exercise. An approach combining exercises to increase strength, flexibility, and aerobic capacity is most likely to be effective for relieving pain and improving function. Current international guidelines recommend therapeutic exercise (land or water based) as "core" and effective management of osteoarthritis. Evidence from this first network meta-analysis, largely based on studies in knee osteoarthritis, indicates that an intervention combining strengthening exercises with flexibility and aerobic exercise is most likely to improve outcomes of pain and function. Further trials of exercise versus no exercise are unlikely to overturn this positive result. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  7. Temas de Física para Ingeniería: Gases ideales

    OpenAIRE

    Beléndez Vázquez, Augusto

    1992-01-01

    Acústica, fluidos y termodinámica: "Gases ideales". Modelo molecular del gas ideal. Interpretación microscópica de la presión y la temperatura. Equipartición de la energía. Capacidades caloríficas de los gases. Proceso adiabático en un gas ideal.

  8. Non-ideal magnetohydrodynamics on a moving mesh

    Science.gov (United States)

    Marinacci, Federico; Vogelsberger, Mark; Kannan, Rahul; Mocz, Philip; Pakmor, Rüdiger; Springel, Volker

    2018-05-01

    In certain astrophysical systems, the commonly employed ideal magnetohydrodynamics (MHD) approximation breaks down. Here, we introduce novel explicit and implicit numerical schemes of ohmic resistivity terms in the moving-mesh code AREPO. We include these non-ideal terms for two MHD techniques: the Powell 8-wave formalism and a constrained transport scheme, which evolves the cell-centred magnetic vector potential. We test our implementation against problems of increasing complexity, such as one- and two-dimensional diffusion problems, and the evolution of progressive and stationary Alfvén waves. On these test problems, our implementation recovers the analytic solutions to second-order accuracy. As first applications, we investigate the tearing instability in magnetized plasmas and the gravitational collapse of a rotating magnetized gas cloud. In both systems, resistivity plays a key role. In the former case, it allows for the development of the tearing instability through reconnection of the magnetic field lines. In the latter, the adopted (constant) value of ohmic resistivity has an impact on both the gas distribution around the emerging protostar and the mass loading of magnetically driven outflows. Our new non-ideal MHD implementation opens up the possibility to study magneto-hydrodynamical systems on a moving mesh beyond the ideal MHD approximation.

  9. Ideal magnetohydrodynamic simulations of unmagnetized dense plasma jet injection into a hot strongly magnetized plasma

    OpenAIRE

    Liu, Wei; Hsu, Scott C.

    2010-01-01

    We present results from three-dimensional ideal magnetohydrodynamic simulations of unmagnetized dense plasma jet injection into a uniform hot strongly magnetized plasma, with the aim of providing insight into core fueling of a tokamak with parameters relevant for ITER and NSTX (National Spherical Torus Experiment). Unmagnetized dense plasma jet injection is similar to compact toroid injection but with much higher plasma density and total mass, and consequently lower required injection velocit...

  10. An Ideal Integrating Bolometer Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to develop a novel detector to enable a new class of far-IR spectroscopic surveys.  The detector, the Ideal Integrating Bolometer (IIB) is able to...

  11. Phase II Pragmatic Randomized Controlled Trial of Patient-Led Therapies (Mirror Therapy and Lower-Limb Exercises) During Inpatient Stroke Rehabilitation.

    Science.gov (United States)

    Tyson, Sarah; Wilkinson, Jack; Thomas, Nessa; Selles, Ruud; McCabe, Candy; Tyrrell, Pippa; Vail, Andy

    2015-10-01

    Patient-led therapy has the potential to increase the amount of therapy patients undertake during stroke rehabilitation and to enhance recovery. Our objective was to assess the feasibility and acceptability of 2 patient-led therapies during the acute stages of stroke care: mirror therapy for the upper limb and lower-limb exercises for the lower limb. This was a blind assessed, multicenter, pragmatic randomized controlled trial of patient-led upper-limb mirror therapy and patient-led lower leg exercises. Stroke survivors with upper and lower limb limitations, undergoing inpatient rehabilitation and able to consent were recruited at least 1 week poststroke. Both interventions proved feasible, with >90% retention. No serious adverse events were reported. Both groups did less therapy than recommended; typically 5 to 15 minutes for 7 days or less. Participants receiving mirror therapy (n = 63) tended to do less practice than those doing lower-limb exercises (n = 31). Those with neglect did 69% less mirror therapy than those without (P = .02), which was not observed in the exercise group. Observed between-group differences were modest but neglect, upper-limb strength, and dexterity showed some improvement in the mirror therapy group. No changes were seen in the lower-limb group. Both patient-led mirror therapy and lower-limb exercises during inpatient stroke care are safe, feasible, and acceptable and warrant further investigation. Practice for 5 to 15 minutes for 7 days is a realistic prescription unless strategies to enhance adherence are included. © The Author(s) 2015.

  12. Minimal prime ideals in semigroups without nilpotent elements

    International Nuclear Information System (INIS)

    Ahsan, J.

    1989-07-01

    The aim of this paper is to obtain a characterization of minimal prime ideals of (non-commutative) semigroups without nilpotent elements analogous to the one for the corresponding class of rings. We also define the notion of symmetric ideals of a semigroup and establish some of their basic properties. 5 refs

  13. Effect of saw palmetto soft gel capsule on lower urinary tract symptoms associated with benign prostatic hyperplasia: a randomized trial in Shanghai, China.

    Science.gov (United States)

    Shi, Rong; Xie, Qiungwen; Gang, X; Lun, Jing; Cheng, Life; Pantuck, Allan; Rao, Jianyu

    2008-02-01

    We determined the effect of Prostataplex in men with lower urinary tract symptoms associated with benign prostatic hyperplasia. A total of 92 Chinese men between 49 and 75 years old with lower urinary tract symptoms were randomly assigned in this double-blind, placebo controlled trial. The 46 patients in the intervention group were given 2 Prostataplex soft gels daily for 12 weeks, while the 46 in the control group were given 2 placebo soft gels for the same time. The treated and control groups appeared to have more than a 95% compliance rate, as judged by counting the remaining pills in the bottle collected at the end of trial months 1 to 3. After 12 weeks of intervention the mean +/- SD maximum urinary flow rate was significantly higher in the treatment group than in the control group (14.07 +/- 2.56 vs 11.74 +/- 1.23 ml per second, p <0.001), while relative urinary resistance was significantly lower in the treatment group than in the control group (2.35 +/- 0.83 vs 3.02 +/- 1.18, p = 0.002). While there was no significant difference in mean prostate volume or International Prostate Symptom Score between the 2 groups, 18 of 46 patients (39.1%) in the treatment group showed an International Prostate Symptom Score improvement (decrease of 3 or greater) after intervention, whereas only 1 of 46 (2.2%) in the control group showed an International Prostate Symptom Score improvement (chi-square test p <0.001). Prostataplex may have short-term effects in improving symptoms and objective measures in Chinese men with lower urinary tract symptoms associated with benign prostatic hyperplasia.

  14. The Ideal of Moral Autonomy

    Directory of Open Access Journals (Sweden)

    Ricardo Marquisio Aguirre

    2017-10-01

    Full Text Available Some elements of the ideal of moral autonomy are discussed in this paper. Such ideal is a key assumption in social practices focused on normative imputation, particularly morality and law. First, a constructivist conception of normativity is introduced, taking reasons as an essential and non-reducible element, and focused on the conceptual features of moral reasons within the normative domain. Then, an idea of moral autonomy based on the self-constitution is developed including three key features: the possibility of responding to reasons based on shared social expectations; the responsibility for certain scope of actions, according to a set of reasons available to the individual and to their maximum extent of expansion; and the need to preserve autonomy as a purpose unifying the set of autonomous actions of moral agents.

  15. Smoothness in Binomial Edge Ideals

    Directory of Open Access Journals (Sweden)

    Hamid Damadi

    2016-06-01

    Full Text Available In this paper we study some geometric properties of the algebraic set associated to the binomial edge ideal of a graph. We study the singularity and smoothness of the algebraic set associated to the binomial edge ideal of a graph. Some of these algebraic sets are irreducible and some of them are reducible. If every irreducible component of the algebraic set is smooth we call the graph an edge smooth graph, otherwise it is called an edge singular graph. We show that complete graphs are edge smooth and introduce two conditions such that the graph G is edge singular if and only if it satisfies these conditions. Then, it is shown that cycles and most of trees are edge singular. In addition, it is proved that complete bipartite graphs are edge smooth.

  16. Relativistic Ideal Clock

    OpenAIRE

    Bratek, Łukasz

    2015-01-01

    Two particularly simple ideal clocks exhibiting intrinsic circular motion with the speed of light and opposite spin alignment are described. The clocks are singled out by singularities of an inverse Legendre transformation for relativistic rotators of which mass and spin are fixed parameters. Such clocks work always the same way, no matter how they move. When subject to high accelerations or falling in strong gravitational fields of black holes, the clocks could be used to test the clock hypo...

  17. IPP-rich milk protein hydrolysate lowers blood pressure in subjects with stage 1 hypertension, a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Kloek Joris

    2010-11-01

    Full Text Available Abstract Background Milk derived peptides have been identified as potential antihypertensive agents. The primary objective was to investigate the effectiveness of IPP-rich milk protein hydrolysates (MPH on reducing blood pressure (BP as well as to investigate safety parameters and tolerability. The secondary objective was to confirm or falsify ACE inhibition as the mechanism underlying BP reductions by measuring plasma renin activity and angiotensin I and II. Methods We conducted a randomized, placebo-controlled, double blind, crossover study including 70 Caucasian subjects with prehypertension or stage 1 hypertension. Study treatments consisted of daily consumption of two capsules MPH1 (each containing 7.5 mg Isoleucine-Proline-Proline; IPP, MPH2 (each containing 6.6 mg Methionine-Alanine-Proline, 2.3 mg Leucine-Proline-Proline, 1.8 mg IPP, or placebo (containing cellulose for 4 weeks. Results In subjects with stage 1 hypertension, MPH1 lowered systolic BP by 3.8 mm Hg (P = 0.0080 and diastolic BP by 2.3 mm Hg (P = 0.0065 compared with placebo. In prehypertensive subjects, the differences in BP between MPH1 and placebo were not significant. MPH2 did not change BP significantly compared with placebo in stage I hypertensive or prehypertensive subjects. Intake of MPHs was well tolerated and safe. No treatment differences in hematology, clinical laboratory parameters or adverse effects were observed. No significant differences between MPHs and placebo were found in plasma renin activity, or angiotensin I and II. Conclusions MPH1, containing IPP and no minerals, exerts clinically relevant BP lowering effects in subjects with stage 1 hypertension. It may be included in lifestyle changes aiming to prevent or reduce high BP. Trial registration ClinicalTrials.gov NCT00471263

  18. Acupuncture lowering blood pressure for secondary prevention of stroke: a study protocol for a multicenter randomized controlled trial.

    Science.gov (United States)

    Du, Yu-Zheng; Gao, Xin-Xin; Wang, Cheng-Ting; Zheng, Hai-Zhen; Lei, Yun; Wu, Meng-Han; Shi, Xue-Min; Ban, Hai-Peng; Gu, Wen-Long; Meng, Xiang-Gang; Wei, Mao-Ti; Hu, Chun-Xiao

    2017-09-15

    Stroke is the prime cause of morbidity and mortality in the general population, and hypertension will increase the recurrence and mortality of stroke. We report a protocol of a pragmatic randomized controlled trial (RCT) using blood pressure (BP)-lowering acupuncture add-on treatment to treat patients with hypertension and stroke. This is a large-scale, multicenter, subject-, assessor- and analyst-blinded, pragmatic RCT. A total of 480 patients with hypertension and ischemic stroke will be randomly assigned to two groups: an experimental group and a control group. The experimental group will receive "HuoXueSanFeng" acupuncture combined with one antihypertensive medication in addition to routine ischemic stroke treatment. The control group will only receive one antihypertensive medication and basic treatments for ischemic stroke. HuoXueSanFeng acupuncture will be given for six sessions weekly for the first 6 weeks and three times weekly for the next 6 weeks. A 9-month follow-up will, thereafter, be conducted. Antihypertensive medication will be adjusted based on BP levels. The primary outcome will be the recurrence of stroke. The secondary outcomes including 24-h ambulatory BP, the TCM syndrome score, the Short Form 36-item Health Survey (SF-36), the National Institute of Health Stroke Scale (NIHSS), as well as the Barthel Index (BI) scale will be assessed at baseline, 6 weeks and 12 weeks post initiating treatments; cardiac ultrasound, carotid artery ultrasound, transcranial Doppler, and lower extremity ultrasound will be evaluated at baseline and 12 weeks after treatment. The safety of acupuncture will also be assessed. We aim to determine the clinical effects of controlling BP for secondary prevention of stroke with acupuncture add-on treatment. ClinicalTrials.gov, ID: NCT02967484 . Registered on 13 February 2017; last updated on 27 June 2017.

  19. Ideal thermodynamic processes of oscillatory-flow regenerative engines will go to ideal stirling cycle?

    Science.gov (United States)

    Luo, Ercang

    2012-06-01

    This paper analyzes the thermodynamic cycle of oscillating-flow regenerative machines. Unlike the classical analysis of thermodynamic textbooks, the assumptions for pistons' movement limitations are not needed and only ideal flowing and heat transfer should be maintained in our present analysis. Under such simple assumptions, the meso-scale thermodynamic cycles of each gas parcel in typical locations of a regenerator are analyzed. It is observed that the gas parcels in the regenerator undergo Lorentz cycle in different temperature levels, whereas the locus of all gas parcels inside the regenerator is the Ericson-like thermodynamic cycle. Based on this new finding, the author argued that ideal oscillating-flow machines without heat transfer and flowing losses is not the Stirling cycle. However, this new thermodynamic cycle can still achieve the same efficiency of the Carnot heat engine and can be considered a new reversible thermodynamic cycle under two constant-temperature heat sinks.

  20. Formation of ideal of legal personality

    Directory of Open Access Journals (Sweden)

    Віта Олександрівна Сліпенчук

    2016-01-01

    Full Text Available Problem setting. In the process of transformation of Ukrainian society towards the assimilation and implementation of basic European values such as human rights, democracy and the rule of law the role of personality that respects the dignity of others and their right to free expression in its multifaceted manifestations becomes more important. Such definitions of it assume the character of the ideal to be pursued, but that has not received adequate expression in people's minds and in practice yet. Since this ideal inextricably links right and personality, enabling the operation of law due to the special qualities of the individual, it can be defined as the ideal of legal personality. It is the formation and realization of such ideal that becomes urgent practical task of our society, which in turn requires a comprehensive theoretical understanding. Recent research and publications analysis. It should be noted that some philosophical aspects of the meaning of legal personality and its formation are revealed in the works of Ukrainian researcher in the field of philosophy of law S.I. Maksimov. However, all actual researches are based on a certain cultural and ideological tradition. The research of  a Polish-American scholar in the history of philosophical and legal thought Andrzej Walicki pays attention to the ideological and methodological potential liberal legal philosophy of the late 19th - early 20th century in the Russian Empire, realization of which, unfortunately, failed because of the violent interruption of this tradition by Bolsheviks. Researches of philosophers of law of that period are of particular significance in this issue: Ukrainian by origin and outlook Bohdan Kistyakivskiy and one of the authors of the Universal Declaration of Human Rights (1948 Serhiy Gessen. It is reconstruction of the concept of "legal personality" in the views of philosophers of law of that period, which is really made for the first time, which will give, as

  1. On prime ideals and associated spectrum of BCK-algebras

    International Nuclear Information System (INIS)

    Ahsan, J.; Thaheem, A.B.; Deeba, E.Y.

    1989-07-01

    In this paper we study prime ideals and define the spectrum of a bounded commutative BCK-algebra. We also obtain a characterization of minimal prime (lattice) ideals of these algebras. (author). 8 refs, 4 tabs

  2. Thermodynamics of a classical ideal gas at arbitrary temperatures

    OpenAIRE

    Pal, Palash B.

    2002-01-01

    We propose a fundamental relation for a classical ideal gas that is valid at all temperatures with remarkable accuracy. All thermodynamical properties of classical ideal gases can be deduced from this relation at arbitrary temperature.

  3. Role of blood pressure and other variables in the differential cardiovascular event rates noted in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA)

    DEFF Research Database (Denmark)

    Poulter, Neil R; Wedel, Hans; Dahlöf, Björn

    2005-01-01

    Results of the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA) show significantly lower rates of coronary and stroke events in individuals allocated an amlodipine-based combination drug regimen than in those allocated an atenolol-based combination drug regimen (HR...... 0.86 and 0.77, respectively). Our aim was to assess to what extent these differences were due to significant differences in blood pressures and in other variables noted after randomisation....

  4. Self-esteem revisited: performance on the implicit relational assessment procedure as a measure of self- versus ideal self-related cognitions in dysphoria.

    Science.gov (United States)

    Remue, Jonathan; De Houwer, Jan; Barnes-Holmes, Dermot; Vanderhasselt, Marie-Anne; De Raedt, Rudi

    2013-01-01

    Although depression is characterised by low self-esteem as measured by questionnaires, research using implicit measures of self-esteem has failed to reveal the expected differences between depressed and non-depressed individuals. In this study, we used an implicit measure which enables the differentiation of ideal self- and actual self-esteem, through the introduction of propositions: "I am" versus "I want to be". We measured implicit relational associations about actual and ideal self in low (N=27) versus high dysphoric (N=29) undergraduates. Our data revealed that dysphoric individuals have a higher ideal self-esteem, and lower actual self-esteem in comparison to healthy participants. The results underscore the need to go beyond simple associations and suggest that the use of individual-specific propositions could enhance our understanding of the implicit measurement of self-esteem. Furthermore, these results underscore the importance of actual versus ideal self-discrepancy theories, which might guide the content of therapeutic interventions.

  5. Multi-axial response of idealized cermets

    International Nuclear Information System (INIS)

    Pickering, E.G.; Bele, E.; Deshpande, V.S.

    2016-01-01

    The yield response of two idealized cermets comprising mono and bi-disperse steel spheres in a Sn/Pb solder matrix has been investigated for a range of axisymmetric stress states. Proportional stress path experiments are reported, from which are extracted the initial yield surfaces and their evolution with increasing plastic strain. The initial yield strength is nearly independent of the hydrostatic pressure but the strain hardening rate increases with stress triaxiality up to a critical value. For higher triaxialities, the responses are independent of hydrostatic pressure. Multi-axial measurements along with X-ray tomography were used to demonstrate that the deformation of these idealized cermets occurs by two competing mechanisms: (i) a granular flow mechanism that operates at low levels of triaxiality, where volumetric dilation occurs under compressive stress states, and (ii) a plastically incompressible mechanism that operates at high stress triaxialities. A phenomenological viscoplastic constitutive model that incorporates both deformation mechanisms is presented. While such multi-axial measurements are difficult for commercial cermets with yield strengths on the order of a few GPa, the form of their constitutive relation is expected to be similar to that of the idealized cermets presented here.

  6. A comparative quantitative analysis of the IDEAL (iterative decomposition of water and fat with echo asymmetry and least-squares estimation) and the CHESS (chemical shift selection suppression) techniques in 3.0 T L-spine MRI

    Science.gov (United States)

    Kim, Eng-Chan; Cho, Jae-Hwan; Kim, Min-Hye; Kim, Ki-Hong; Choi, Cheon-Woong; Seok, Jong-min; Na, Kil-Ju; Han, Man-Seok

    2013-03-01

    This study was conducted on 20 patients who had undergone pedicle screw fixation between March and December 2010 to quantitatively compare a conventional fat suppression technique, CHESS (chemical shift selection suppression), and a new technique, IDEAL (iterative decomposition of water and fat with echo asymmetry and least squares estimation). The general efficacy and usefulness of the IDEAL technique was also evaluated. Fat-suppressed transverse-relaxation-weighed images and longitudinal-relaxation-weighted images were obtained before and after contrast injection by using these two techniques with a 1.5T MR (magnetic resonance) scanner. The obtained images were analyzed for image distortion, susceptibility artifacts and homogenous fat removal in the target region. The results showed that the image distortion due to the susceptibility artifacts caused by implanted metal was lower in the images obtained using the IDEAL technique compared to those obtained using the CHESS technique. The results of a qualitative analysis also showed that compared to the CHESS technique, fewer susceptibility artifacts and more homogenous fat removal were found in the images obtained using the IDEAL technique in a comparative image evaluation of the axial plane images before and after contrast injection. In summary, compared to the CHESS technique, the IDEAL technique showed a lower occurrence of susceptibility artifacts caused by metal and lower image distortion. In addition, more homogenous fat removal was shown in the IDEAL technique.

  7. Jung's Red Book and its relation to aspects of German idealism.

    Science.gov (United States)

    Bishop, Paul

    2012-06-01

    The late nineteenth century saw a renaissance of interest in the thought of the German Romantic philosopher, F.W.J. Schelling. This paper takes Jung's engagement with Schelling and his awareness of Schellingian ideas and interests (notably, the mysterious Kabeiroi worshipped at Samothrace) as its starting-point. It goes on to argue that a key set of problematics in German Idealism - the relation between freedom and necessity, between science and art, and ultimately between realism and idealism - offers a useful conceptual framework within which to approach Jung's Red Book. For the problem of the ideal is central to this work, which can be read as a journey from eternal ideals to the ideal of eternity. (Although the term 'idealism' has at least four distinct meanings, their distinct senses can be related in different ways to Jung's thinking.) The eloquent embrace of idealism by F.T. Vischer in a novel, Auch Einer, for which Jung had the highest praise, reminds us of the persistence of this tradition, which is still contested and debated in the present day. © 2012, The Society of Analytical Psychology.

  8. A Generalized Deduction of the Ideal-Solution Model

    Science.gov (United States)

    Leo, Teresa J.; Perez-del-Notario, Pedro; Raso, Miguel A.

    2006-01-01

    A new general procedure for deriving the Gibbs energy of mixing is developed through general thermodynamic considerations, and the ideal-solution model is obtained as a special particular case of the general one. The deduction of the Gibbs energy of mixing for the ideal-solution model is a rational one and viewed suitable for advanced students who…

  9. An Effectiveness Trial of a Selected Dissonance-Based Eating Disorder Prevention Program for Female High School Students: Long-Term Effects

    Science.gov (United States)

    Stice, Eric; Rohde, Paul; Shaw, Heather; Gau, Jeff

    2011-01-01

    Objective: Efficacy trials found that a dissonance-based eating disorder prevention program in which female high school and college students with body image concerns critique the thin ideal reduced eating disorder risk factors, eating disorder symptoms, and future eating disorder onset. The present effectiveness trial tested whether this program…

  10. Brahmanical idealism, anarchical individualism, and the dynamics of Indian negotiating behavior

    DEFF Research Database (Denmark)

    Kumar, Rajesh

    2004-01-01

    The article analyzes the implications of the Indian mind set on the dynamics of the Indian negotiating behavior. I argue that the constructs of Brahmanical idealism and anarchical individualism capture the nature of the Indian mind set. Brahmanical idealism reflects the tendency of the decision...... focuses on the purity of the mental world, anarchical individualism lays primacy of attaining the ideal solution through absolutist forms of interpersonal behavior. That is to say, since each individual is engaged in searching for the ideal solution , and furthermore as each individuals ideal solution...... is either no better or worse than that of their counterpart, the attainment of this ideal is problematical because under these conditions cooperative behavior is a rarity. In this sense anarchic individualism fragments rather than enhances total effort, thereby draining energy away from the system. I...

  11. Expanding the Evidence Base: Comparing Randomized Controlled Trials and Observational Studies of Statins

    NARCIS (Netherlands)

    Atar, Dan; Ong, Seleen; Lansberg, Peter J.

    2015-01-01

    It is widely accepted that randomized controlled trials (RCTs) are the gold standard for demonstrating the efficacy of a given therapy (results under ideal conditions). Observational studies, on the other hand, can complement this by demonstrating effectiveness (results under real-world conditions).

  12. Media-portrayed idealized images, self-objectification, and eating behavior.

    Science.gov (United States)

    Monro, Fiona J; Huon, Gail F

    2006-11-01

    This study examined the effects of media-portrayed idealized images on young women's eating behavior. The study compared the effects for high and low self-objectifiers. 72 female university students participated in this experiment. Six magazine advertisements featuring idealized female models were used as the experimental stimuli, and the same six advertisements with the idealized body digitally removed became the control stimuli. Eating behavior was examined using a classic taste test that involved both sweet and savory food. Participants' restraint status was assessed. We found that total food intake after exposure was the same in the body present and absent conditions. There were also no differences between high and low self-objectifiers' total food intake. However, for the total amount of food consumed and for sweet food there were significant group by condition interaction effects. High self-objectifiers ate more food in the body present than the body absent condition. In contrast, low self-objectifiers ate more food in the body absent than in the body present condition. Restraint status was not found to moderate the relationship between exposure to idealized images the amount of food consumed. Our results indicate that exposure to media-portrayed idealized images can lead to changes in eating behavior and highlight the complexity of the association between idealized image exposure and eating behavior. These results are discussed in terms of their implications for the prevention of dieting-related disorders.

  13. Bilateral control of master-slave manipulators for ideal kinesthetic coupling

    International Nuclear Information System (INIS)

    Yokokohji, Yasuyoshi; Yoshikawa, Tsuneo

    1991-01-01

    The way to control master-slave manipulators affects considerably to the maneuverability of the master-slave systems. The ideal state of master-slave systems can be regarded that the operator can operate the system as if he were directly manipulating the object which is actually existing at the remote site. In other saying, the system must be coupled with the operator to give the ideal kinesthetic sense so that he can perceive the object. So far, several researches discussed about the ideal states of master-slave systems in their own descriptions. However, there is few exact discussion about how close the ideal state can be achieved actually or what kind of control scheme should be designed in order to achieve it. In this paper, we propose a control scheme which can achieve the ideal kinesthetic coupling with the operator and realize three ideal responses which were previously defined by the authors. Secondly, we show the stability of the system controlled by the proposed scheme by using the concept of passivity. We then discuss about the system stability when the sensor signals are pass through the filters. Lastly, the validity of the proposed scheme is confirmed by simulations. (author)

  14. Bilateral control of master-slave manipulators for ideal kinesthetic coupling

    Energy Technology Data Exchange (ETDEWEB)

    Yokokohji, Yasuyoshi; Yoshikawa, Tsuneo (Kyoto Univ. (Japan). Faculty of Engineering)

    1991-01-01

    The way to control master-slave manipulators affects considerably to the maneuverability of the master-slave systems. The ideal state of master-slave systems can be regarded that the operator can operate the system as if he were directly manipulating the object which is actually existing at the remote site. In other saying, the system must be coupled with the operator to give the ideal kinesthetic sense so that he can perceive the object. So far, several researches discussed about the ideal states of master-slave systems in their own descriptions. However, there is few exact discussion about how close the ideal state can be achieved actually or what kind of control scheme should be designed in order to achieve it. In this paper, we propose a control scheme which can achieve the ideal kinesthetic coupling with the operator and realize three ideal responses which were previously defined by the authors. Secondly, we show the stability of the system controlled by the proposed scheme by using the concept of passivity. We then discuss about the system stability when the sensor signals are pass through the filters. Lastly, the validity of the proposed scheme is confirmed by simulations. (author).

  15. Performance Analyses of IDEAL Algorithm on Highly Skewed Grid System

    Directory of Open Access Journals (Sweden)

    Dongliang Sun

    2014-03-01

    Full Text Available IDEAL is an efficient segregated algorithm for the fluid flow and heat transfer problems. This algorithm has now been extended to the 3D nonorthogonal curvilinear coordinates. Highly skewed grids in the nonorthogonal curvilinear coordinates can decrease the convergence rate and deteriorate the calculating stability. In this study, the feasibility of the IDEAL algorithm on highly skewed grid system is analyzed by investigating the lid-driven flow in the inclined cavity. It can be concluded that the IDEAL algorithm is more robust and more efficient than the traditional SIMPLER algorithm, especially for the highly skewed and fine grid system. For example, at θ = 5° and grid number = 70 × 70 × 70, the convergence rate of the IDEAL algorithm is 6.3 times faster than that of the SIMPLER algorithm, and the IDEAL algorithm can converge almost at any time step multiple.

  16. Ideal cardiovascular health status and its association with socioeconomic factors in Chinese adults in Shandong, China

    Directory of Open Access Journals (Sweden)

    J. Ren

    2016-09-01

    Full Text Available Abstract Background Cardiovascular disease (CVD is the leading cause of morbidity and mortality in the world. In 2010, a goal released by the American Heart Association (AHA Committee focused on the primary reduction in cardiovascular risk. Methods Data collected from 7683 men and 7667 women aged 18–69 years were analyzed. The distribution of ideal cardiovascular health metrics based on 7 cardiovascular disease risk factors or health behaviors in according to the definition of AHA was evaluated among the subjects. The association of the socioeconomic factors on the prevalence of meeting 5 or more ideal cardiovascular health metrics was estimated by logistic regression analysis, and a chi-square test for categorical variables and the general linear model (GLM procedure for continuous variables were used to compare differences in prevalence and in means among genders. Results Seven of 15350 participants (0.05 % met all 7 cardiovascular health metrics. The women had a higher proportion of meeting 5 or more ideal health metrics compared with men (32.67 VS.14.27 %. The subjects with a higher education and income level had a higher proportion of meeting 5 or more ideal health metrics than the subjects with a lower education and income level. A comparison between subjects with meeting 5 or more ideal cardiovascular health metrics with subjects meeting 4 or fewer ideal cardiovascular health metrics reveals that adjusted odds ratio [OR, 95 % confidence intervals (95 % CI] was 1.42 (0.95, 2.21 in men and 2.59 (1.74, 3.87 in women for higher education and income, respectively. Conclusions The prevalence of meeting all 7 cardiovascular health metrics was low in the adult population. Women, young subjects, and those with higher levels of education or income tend to have a greater number of the ideal cardiovascular health metrics. Higher socioeconomic status was associated with an increasing prevalence of meeting 5 or more cardiovascular health metrics

  17. Randomized, double-blind, placebo-controlled trial of saw palmetto in men with lower urinary tract symptoms.

    Science.gov (United States)

    Gerber, G S; Kuznetsov, D; Johnson, B C; Burstein, J D

    2001-12-01

    To assess the effects of saw palmetto on urinary symptoms, sexual function, and urinary flow rate in men with lower urinary tract symptoms using a double-blind, randomized, placebo-controlled trial. The eligible patients were 45 years of age or older and had an International Prostate Symptom Score of 8 or greater. After a 1-month placebo run-in period, 85 men were randomized to receive saw palmetto or placebo for 6 months. Patients were evaluated using the International Prostate Symptom Score, a sexual function questionnaire, and by measurement of the urinary flow rate. The mean symptom score decreased from 16.7 to 12.3 in the saw palmetto group compared with 15.8 to 13.6 in the placebo group (P = 0.038). The quality-of-life score improved to a greater degree in the saw palmetto group, but this difference was not statistically significant. No change occurred in the sexual function questionnaire results in either group. The peak flow rate increased by 1.0 mL/s and 1.4 mL/s in the saw palmetto and placebo groups, respectively (P = 0.73). Saw palmetto led to a statistically significant improvement in urinary symptoms in men with lower urinary tract symptoms compared with placebo. Saw palmetto had no measurable effect on the urinary flow rates. The mechanism by which saw palmetto improves urinary symptoms remains unknown.

  18. The Slice Algorithm For Irreducible Decomposition of Monomial Ideals

    DEFF Research Database (Denmark)

    Roune, Bjarke Hammersholt

    2009-01-01

    Irreducible decomposition of monomial ideals has an increasing number of applications from biology to pure math. This paper presents the Slice Algorithm for computing irreducible decompositions, Alexander duals and socles of monomial ideals. The paper includes experiments showing good performance...

  19. Brahmanical idealism, anarchical individualism, and the dynamics of Indian negotiating behavior

    DEFF Research Database (Denmark)

    Kumar, Rajesh

    1999-01-01

    to seek the most perfect solution. Any discrepancies between the realities of the external world and the logic of the inner world as manifested through a search for the ideal solution are not problematical for it is only the inner world that defines the true reality. If Brahmanical idealism focuses...... on the purity of the mental world, anarchical individualism lays emphasis on the primacy of attaining the ideal solution through absolutist forms of interpersonal behavior. That is to say, since each individual is engaged in searching for the ideal solution, and furthermore, as each individual's ideal solution...... is either no better or no worse than that of their counterpart, the attainment of this ideal is problematic because under these conditions cooperative behavior is a rarity. In this sense, anarchic individualism fragments rather than enhances total effort, thereby draining energy away from the system. I...

  20. The American Heart Association Ideal Cardiovascular Health and Incident Type 2 Diabetes Mellitus Among Blacks: The Jackson Heart Study.

    Science.gov (United States)

    Effoe, Valery S; Carnethon, Mercedes R; Echouffo-Tcheugui, Justin B; Chen, Haiying; Joseph, Joshua J; Norwood, Arnita F; Bertoni, Alain G

    2017-06-21

    The concept of ideal cardiovascular health (CVH), defined by the American Heart Association primarily for coronary heart disease and stroke prevention, may apply to diabetes mellitus prevention among blacks. Our sample included 2668 adults in the Jackson Heart Study with complete baseline data on 6 of 7 American Heart Association CVH metrics (body mass index, healthy diet, smoking, total cholesterol, blood pressure, and physical activity). Incident diabetes mellitus was defined as fasting glucose ≥126 mg/dL, physician diagnosis, use of diabetes mellitus drugs, or glycosylated hemoglobin ≥6.5%. A summary CVH score from 0 to 6, based on presence/absence of ideal CVH metrics, was derived for each participant. Cox regression was used to estimate adjusted hazard ratios. Mean age was 55 years (65% women) with 492 incident diabetes mellitus events over 7.6 years (24.6 cases/1000 person-years). Three quarters of participants had only 1 or 2 ideal CVH metrics; no participant had all 6. After adjustment for demographic factors (age, sex, education, and income) and high-sensitivity C-reactive protein, each additional ideal CVH metric was associated with a 17% diabetes mellitus risk reduction (hazard ratio, 0.83; 95% CI, 0.74-0.93). The association was attenuated with further adjustment for homeostasis model assessment for insulin resistance (hazard ratio, 0.89; 95% CI, 0.79-1.00). Compared with participants with 1 or no ideal CVH metric, diabetes mellitus risk was 15% and 37% lower in those with 2 and ≥3 ideal CVH metrics, respectively. The AHA concept of ideal CVH is applicable to diabetes mellitus prevention among blacks. These associations were largely explained by insulin resistance. © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

  1. On the Prime Ideals of C [0, 1

    Indian Academy of Sciences (India)

    It is well known that the set C[0, 1] of real-valuedcontinuous functions on the closed interval [0, 1]has a natural ring structure. Its maximal idealsare known to be points. Here we show thatalthough there exist prime ideals which are notmaximal, the zero set is again a singleton. In particular,each prime ideal is contained in a ...

  2. A Novel Approach toward Fuzzy Generalized Bi-Ideals in Ordered Semigroups

    Directory of Open Access Journals (Sweden)

    Faiz Muhammad Khan

    2014-01-01

    Full Text Available In several advanced fields like control engineering, computer science, fuzzy automata, finite state machine, and error correcting codes, the use of fuzzified algebraic structures especially ordered semigroups plays a central role. In this paper, we introduced a new and advanced generalization of fuzzy generalized bi-ideals of ordered semigroups. These new concepts are supported by suitable examples. These new notions are the generalizations of ordinary fuzzy generalized bi-ideals of ordered semigroups. Several fundamental theorems of ordered semigroups are investigated by the properties of these newly defined fuzzy generalized bi-ideals. Further, using level sets, ordinary fuzzy generalized bi-ideals are linked with these newly defined ideals which is the most significant part of this paper.

  3. The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial

    DEFF Research Database (Denmark)

    Baigent, Colin; Landray, Martin J; Reith, Christina

    2011-01-01

    Lowering LDL cholesterol with statin regimens reduces the risk of myocardial infarction, ischaemic stroke, and the need for coronary revascularisation in people without kidney disease, but its effects in people with moderate-to-severe kidney disease are uncertain. The SHARP trial aimed to assess...

  4. The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial

    DEFF Research Database (Denmark)

    Baigent, Colin; Landray, Martin J; Reith, Christina

    2011-01-01

    Lowering LDL cholesterol with statin regimens reduces the risk of myocardial infarction, ischaemic stroke, and the need for coronary revascularisation in people without kidney disease, but its effects in people with moderate-to-severe kidney disease are uncertain. The SHARP trial aimed to assess ...

  5. Mixed multiplicities for arbitrary ideals and generalized Buchsbaum-Rim multiplicities

    International Nuclear Information System (INIS)

    Callejas-Bedregal, R.; Jorge Perez, V.H.

    2005-12-01

    We introduce first the notion of mixed multiplicities for arbitrary ideals in a local d-dimensional noetherian ring (A, m) which, in some sense, generalizes the concept of mixed multiplicities for m-primary ideals. We also generalize Teissier's Product Formula for a set of arbitrary ideals. We also extend the notion of the Buchsbaum-Rim multiplicity (in short, we write BR-multiplicity) of a submodule of a free module to the case where the submodule no longer has finite colength. For a submodule M of A p we introduce a sequence e BR k (M), k = 0,...,d + p - 1 which in the ideal case coincides with the multiplicity sequence c 0 (I, A),...,c d (I, A) defined for an arbitrary ideal I of A by Achilles and Manaresi in [AM]. In case that M has finite colength in A p and it is totally decomposable we prove that our BR-multiplicity sequence essentially falls into the standard BR-multiplicity of M. (author)

  6. Temperature and the Ideal Gas

    Science.gov (United States)

    Daisley, R. E.

    1973-01-01

    Presents some organized ideas in thermodynamics which are suitable for use with high school (GCE A level or ONC) students. Emphases are placed upon macroscopic observations and intimate connection of the modern definition of temperature with the concept of ideal gas. (CC)

  7. The impact of exposure to the thin-ideal media image on women.

    Science.gov (United States)

    Hawkins, Nicole; Richards, P Scott; Granley, H Mac; Stein, David M

    2004-01-01

    The purpose of this study was to experimentally examine the effects of exposure to the thin-ideal body image on women's affect, self-esteem, body satisfaction, eating disorder symptoms, and level of internalization of the thin-ideal. College women (N=145) were randomly exposed to photographs from popular magazines containing either thin-ideal images or neutral images. Exposure to thin-ideal magazine images increased body dissatisfaction, negative mood states, and eating disorder symptoms and decreased self-esteem, although it did not cause more internalization of the thin-ideal. Exposure to thin-ideal media images may contribute to the development of eating disorders by causing body dissatisfaction, negative moods, low self-esteem, and eating disorders symptoms among women.

  8. Perceptions of ideal and former partner's personality and similarity

    NARCIS (Netherlands)

    Dijkstra, Pieternel; Barelds, Dick P.H.

    2010-01-01

    The present study aimed to test predictions based on both the ‗similarity-attraction‘ hypothesis and the ‗attraction-similarity‘ hypothesis, by studying perceptions of ideal and former partners. Based on the ‗similarity-attraction‘ hypothesis, we expected individuals to desire ideal partners who are

  9. Non-Ideal Behavior in Solvent Extraction

    International Nuclear Information System (INIS)

    Zalupski, Peter

    2011-01-01

    This report presents a summary of the work performed to meet FCR and D level 3 milestone M31SW050801, 'Complete the year-end report summarizing FY11 experimental and modeling activities.' This work was carried out under the auspices of the Non-Ideality in Solvent Extraction Systems FCR and D work package. The report summarizes our initial considerations of potential influences that non-ideal chemistry may impose on computational prediction of outcomes in solvent extraction systems. The report is packaged into three separate test cases where a robustness of the prediction by SXFIT program is under scrutiny. The computational exercises presented here emphasize the importance of accurate representation of both an aqueous and organic mixtures when modeling liquid-liquid distribution systems. Case No.1 demonstrates that non-ideal behavior of HDEHP in aliphatic diluents, such as n-dodecane, interferes with the computation. Cases No.2 and No.3 focus on the chemical complexity of aqueous electrolyte mixtures. Both exercises stress the need for an improved thermodynamic model of an aqueous environment present in the europium distribution experiments. Our efforts for year 2 of this project will focus on the improvements of aqueous and non-aqueous solution models using fundamental physical properties of mixtures acquired experimentally in our laboratories.

  10. Non-Ideal Behavior in Solvent Extraction

    Energy Technology Data Exchange (ETDEWEB)

    Peter Zalupski

    2011-09-01

    This report presents a summary of the work performed to meet FCR&D level 3 milestone M31SW050801, 'Complete the year-end report summarizing FY11 experimental and modeling activities.' This work was carried out under the auspices of the Non-Ideality in Solvent Extraction Systems FCR&D work package. The report summarizes our initial considerations of potential influences that non-ideal chemistry may impose on computational prediction of outcomes in solvent extraction systems. The report is packaged into three separate test cases where a robustness of the prediction by SXFIT program is under scrutiny. The computational exercises presented here emphasize the importance of accurate representation of both an aqueous and organic mixtures when modeling liquid-liquid distribution systems. Case No.1 demonstrates that non-ideal behavior of HDEHP in aliphatic diluents, such as n-dodecane, interferes with the computation. Cases No.2 and No.3 focus on the chemical complexity of aqueous electrolyte mixtures. Both exercises stress the need for an improved thermodynamic model of an aqueous environment present in the europium distribution experiments. Our efforts for year 2 of this project will focus on the improvements of aqueous and non-aqueous solution models using fundamental physical properties of mixtures acquired experimentally in our laboratories.

  11. Fäder i Sovjetryssland: Ideal, känslor och praktik

    Directory of Open Access Journals (Sweden)

    Helene Carlbäck

    2017-11-01

    Full Text Available This article investigates fatherhood ideals and practices in late Soviet Russia, 1960–1989. For the theoretical basis, dominant ideals on masculinity and fatherhood have been derived from the rich but predominantly Western research literature of the past three decades. These are used as guiding tools in examining the research material for this study: the monthly magazine Semia i shkola. Zhurnal dlia roditelei (Family and School; Journal for Parents and eleven in-depth interviews with men in Russia on their memories of fatherhood in the 1960s–1980s. The research questions are: What did the ideal image of fatherhood look like in this period? What remembered practices do respondents communicate in interviews, and how do these relate to dominant public/official ideals of the time? Are there differences in the emphasis on various aspects of fatherhood ideals/practices between public discourses and the accounts given by these men? The interview narratives yield a multifaceted picture, with both coinciding and contradictory representations of the respondents’ ideal images, on the one hand, and remembered practices, on the other. Possible explanations are then discussed. In conclusion, Soviet Russian fatherhood is tentatively contextualized within the framework of research results on Western fatherhood.

  12. IDEALS GENERATED BY LINEAR FORMS AND SYMMETRIC ALGEBRAS

    Directory of Open Access Journals (Sweden)

    Gaetana Restuccia

    2016-01-01

    Full Text Available We consider ideals generated by linear forms in the variables X1 : : : ;Xn in the polynomial ring R[X1; : : : ;Xn], being R a commutative, Noetherian ring with identity. We investigate when a sequence a1; a2; : : : ; am of linear forms is an ssequence, in order to compute algebraic invariants of the symmetric algebra of the ideal I = (a1; a2; : : : ; am.

  13. Probiotics for the treatment of upper and lower respiratory-tract infections in children: systematic review based on randomized clinical trials

    Directory of Open Access Journals (Sweden)

    Georgia Véras de Araujo

    2015-10-01

    Full Text Available ABSTRACT OBJECTIVES: Evaluate the effect of probiotics on the symptoms, duration of disease, and the occurrence of new episodes of upper and lower respiratory infections in healthy children. SOURCES: In order to identify eligible randomized controlled trials, two reviewers accessed four electronic databases [MEDLINE/PubMed, Scopus (Elsevier, Web of Science, and Cochrane (Cochrane VHL], as well as ClinicalTrials.gov until January 2015. Descriptors were determined by using the Medical Subject Headings tool, following the same search protocol. SUMMARY OF THE FINDINGS: Studies showed to be heterogeneous regarding strains of probiotics, the mode of administration, the time of use, and outcomes. The present review identified 11 peer-reviewed, randomized clinical trials, which analyzed a total of 2417 children up to 10 incomplete years of age. In the analysis of the studies, reduction in new episodes of disease was a favorable outcome for the use of probiotics in the treatment of respiratory infections in children. It is noteworthy that most of these studies were conducted in developed countries, with basic sanitation, health care, and strict, well-established and well-organized guidelines on the use of probiotics. Adverse effects were rarely reported, demonstrating probiotics to be safe. CONCLUSIONS: Despite the encouraging results - reducing new episodes of respiratory infections - the authors emphasize the need for further research, especially in developing countries, where rates of respiratory infections in children are higher when compared to the high per capita-income countries identified in this review.

  14. Lower-extremity resistance training on unstable surfaces improves proxies of muscle strength, power and balance in healthy older adults: a randomised control trial

    Directory of Open Access Journals (Sweden)

    Nils Eckardt

    2016-11-01

    Full Text Available Abstract Background It is well documented that both balance and resistance training have the potential to mitigate intrinsic fall risk factors in older adults. However, knowledge about the effects of simultaneously executed balance and resistance training (i.e., resistance training conducted on unstable surfaces [URT] on lower-extremity muscle strength, power and balance in older adults is insufficient. The objective of the present study was to compare the effects of machine-based stable resistance training (M-SRT and two types of URT, i.e., machine-based (M-URT and free-weight URT (F-URT, on measures of lower-extremity muscle strength, power and balance in older adults. Methods Seventy-five healthy community-dwelling older adults aged 65–80 years, were assigned to three intervention groups: M-SRT, M-URT and F-URT. Over a period of ten weeks, all participants exercised two times per week with each session lasting ~60 min. Tests included assessment of leg muscle strength (e.g., maximal isometric leg extension strength, power (e.g., chair rise test and balance (e.g., functional reach test, carried out before and after the training period. Furthermore, maximal training load of the squat-movement was assessed during the last training week. Results Maximal training load of the squat-movement was significantly lower in F-URT in comparison to M-SRT and M-URT. However, lower-extremity resistance training conducted on even and uneven surfaces meaningfully improved proxies of strength, power and balance in all groups. M-URT produced the greatest improvements in leg extension strength and F-URT in the chair rise test and functional reach test. Conclusion Aside from two interaction effects, overall improvements in measures of lower-extremity muscle strength, power and balance were similar across training groups. Importantly, F-URT produced similar results with considerably lower training load as compared to M-SRT and M-URT. Concluding, F-URT seems an

  15. A constructive approach to minimal free resolutions of path ideals of trees

    Directory of Open Access Journals (Sweden)

    Rachelle R. Bouchat

    2017-01-01

    Full Text Available For a rooted tree $\\Gamma$, we consider path ideals of $\\Gamma$, which are ideals that are generated by all directed paths of a fixed length in $\\Gamma$. In this paper, we provide a combinatorial description of the minimal free resolution of these path ideals. In particular, we provide a class of subforests of $\\Gamma$ that are in one-to-one correspondence with the multi-graded Betti numbers of the path ideal as well as providing a method for determining the projective dimension and the Castelnuovo-Mumford regularity of a given path ideal.

  16. A full ranking for decision making units using ideal and anti-ideal points in DEA.

    Science.gov (United States)

    Barzegarinegad, A; Jahanshahloo, G; Rostamy-Malkhalifeh, M

    2014-01-01

    We propose a procedure for ranking decision making units in data envelopment analysis, based on ideal and anti-ideal points in the production possibility set. Moreover, a model has been introduced to compute the performance of a decision making unit for these two points through using common set of weights. One of the best privileges of this method is that we can make ranking for all decision making units by solving only three programs, and also solving these programs is not related to numbers of decision making units. One of the other advantages of this procedure is to rank all the extreme and nonextreme efficient decision making units. In other words, the suggested ranking method tends to seek a set of common weights for all units to make them fully ranked. Finally, it was applied for different sets holding real data, and then it can be compared with other procedures.

  17. On the relations between parents' ideals and children's autonomy

    NARCIS (Netherlands)

    de Ruyter, D.J.; Schinkel, A.

    2013-01-01

    In this article Doret J. de Ruyter and Anders Schinkel argue that parents' ideals can enhance children's autonomy, but that they may also have a detrimental effect on the development of children's autonomy. After describing the concept of ideals and elucidating a systems theoretical conception of

  18. Ideal Based Cyber Security Technical Metrics for Control Systems

    Energy Technology Data Exchange (ETDEWEB)

    W. F. Boyer; M. A. McQueen

    2007-10-01

    Much of the world's critical infrastructure is at risk from attack through electronic networks connected to control systems. Security metrics are important because they provide the basis for management decisions that affect the protection of the infrastructure. A cyber security technical metric is the security relevant output from an explicit mathematical model that makes use of objective measurements of a technical object. A specific set of technical security metrics are proposed for use by the operators of control systems. Our proposed metrics are based on seven security ideals associated with seven corresponding abstract dimensions of security. We have defined at least one metric for each of the seven ideals. Each metric is a measure of how nearly the associated ideal has been achieved. These seven ideals provide a useful structure for further metrics development. A case study shows how the proposed metrics can be applied to an operational control system.

  19. Ideal affect in daily life: implications for affective experience, health, and social behavior.

    Science.gov (United States)

    Tsai, Jeanne L

    2017-10-01

    Over the last decade, researchers have increasingly demonstrated that ideal affect-the affective states that people value and ideally want to feel-shapes different aspects of daily life. Here I briefly review Affect Valuation Theory (AVT), which integrates ideal affect into existing models of affect and emotion by identifying the causes and consequences of variation in ideal affect. I then describe recent research that applies AVT to the valuation of negative states as well as more complex states, examines how ideal affect shapes momentary affective experience, suggests that ideal affect has both direct and indirect effects on health, and illustrates that people's ideal affect shapes how they judge and respond to others. Finally, I discuss the implications of cultural and individual differences in ideal affect for clinical, educational, work, and leisure settings. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Folic Acid and Creatine as Therapeutic Approaches to Lower Blood Arsenic: A Randomized Controlled Trial.

    Science.gov (United States)

    Peters, Brandilyn A; Hall, Megan N; Liu, Xinhua; Parvez, Faruque; Sanchez, Tiffany R; van Geen, Alexander; Mey, Jacob L; Siddique, Abu B; Shahriar, Hasan; Uddin, Mohammad Nasir; Islam, Tariqul; Balac, Olgica; Ilievski, Vesna; Factor-Litvak, Pam; Graziano, Joseph H; Gamble, Mary V

    2015-12-01

    The World Health Organization estimates that > 140 million people worldwide are exposed to arsenic (As)-contaminated drinking water. As undergoes biologic methylation, which facilitates renal As elimination. In folate-deficient individuals, this process is augmented by folic acid (FA) supplementation, thereby lowering blood As (bAs). Creatinine concentrations in urine are a robust predictor of As methylation patterns. Although the reasons for this are unclear, creatine synthesis is a major consumer of methyl donors, and this synthesis is down-regulated by dietary/supplemental creatine. Our aim was to determine whether 400 or 800 μg FA and/or creatine supplementation lowers bAs in an As-exposed Bangladeshi population. We conducted a clinical trial in which 622 participants were randomized to receive 400 μg FA, 800 μg FA, 3 g creatine, 3 g creatine+400 μg FA, or placebo daily. All participants received an As-removal filter on enrollment, and were followed for 24 weeks. After the 12th week, half of the two FA groups were switched to placebo to evaluate post-treatment bAs patterns. Linear models with repeated measures indicated that the decline in ln(bAs) from baseline in the 800-μg FA group exceeded that of the placebo group (weeks 1-12: β= -0.09, 95% CI: -0.18, -0.01; weeks 13-24: FA continued: β= -0.12, 95% CI: -0.24, -0.00; FA switched to placebo: β= -0.14, 95% CI: -0.26, -0.02). There was no rebound in bAs related to cessation of FA supplementation. Declines in bAs observed in the remaining treatment arms were not significantly different from those of the placebo group. In this mixed folate-deficient/replete study population, 12- and 24-week treatment with 800 μg (but not 400 μg) FA lowered bAs to a greater extent than placebo; this was sustained 12 weeks after FA cessation. In future studies, we will evaluate whether FA and/or creatine altered As methylation profiles.

  1. Impact of a cancer clinical trials web site on discussions about trial participation: a cluster randomized trial.

    Science.gov (United States)

    Dear, R F; Barratt, A L; Askie, L M; Butow, P N; McGeechan, K; Crossing, S; Currow, D C; Tattersall, M H N

    2012-07-01

    Cancer patients want access to reliable information about currently recruiting clinical trials. Oncologists and their patients were randomly assigned to access a consumer-friendly cancer clinical trials web site [Australian Cancer Trials (ACT), www.australiancancertrials.gov.au] or to usual care in a cluster randomized controlled trial. The primary outcome, measured from audio recordings of oncologist-patient consultations, was the proportion of patients with whom participation in any clinical trial was discussed. Analysis was by intention-to-treat accounting for clustering and stratification. Thirty medical oncologists and 493 patients were recruited. Overall, 46% of consultations in the intervention group compared with 34% in the control group contained a discussion about clinical trials (P=0.08). The mean consultation length in both groups was 29 min (P=0.69). The proportion consenting to a trial was 10% in both groups (P=0.65). Patients' knowledge about randomized trials was lower in the intervention than the control group (mean score 3.0 versus 3.3, P=0.03) but decisional conflict scores were similar (mean score 42 versus 43, P=0.83). Good communication between patients and physicians is essential. Within this context, a web site such as Australian Cancer Trials may be an important tool to encourage discussion about clinical trial participation.

  2. Hollywood’s Terror Industry: Idealized beauty and The Bluest Eye

    Directory of Open Access Journals (Sweden)

    E C Koch

    2014-07-01

    Full Text Available Toni Morrison’s novel The Bluest Eye (1970 examines the effects of 1940s American white cultural hegemony on her black characters: Claudia, Pauline, and Pecola. The dominant influence of white society, specifically white ideals of beauty, are perpetuated through film, and exemplified by such actresses as Shirley Temple and Greta Garbo. The terrifying nature of the Hollywood ideal is borne from its influence and ubiquity, and is highlighted by Pecola’s deranged pursuit of this impossible standard of beauty. Ultimately by attempting to realize this paradigm, blacks are disenfranchised while the ideal is recharged with the power of those who continue to pursue it. Keywords:The Bluest Eye, Racial Hegemony, Film Studies, Terror, Ideals of Beauty.

  3. Clinical Trials

    Medline Plus

    Full Text Available ... study explored whether the benefits of lowering high blood pressure in the elderly outweighed the risks. Other examples of clinical trials that test principles or strategies include studies that explore whether ...

  4. Ideal Standards, Acceptance, and Relationship Satisfaction: Latitudes of Differential Effects

    Directory of Open Access Journals (Sweden)

    Asuman Buyukcan-Tetik

    2017-09-01

    Full Text Available We examined whether the relations of consistency between ideal standards and perceptions of a current romantic partner with partner acceptance and relationship satisfaction level off, or decelerate, above a threshold. We tested our hypothesis using a 3-year longitudinal data set collected from heterosexual newlywed couples. We used two indicators of consistency: pattern correspondence (within-person correlation between ideal standards and perceived partner ratings and mean-level match (difference between ideal standards score and perceived partner score. Our results revealed that pattern correspondence had no relation with partner acceptance, but a positive linear/exponential association with relationship satisfaction. Mean-level match had a significant positive association with actor’s acceptance and relationship satisfaction up to the point where perceived partner score equaled ideal standards score. Partner effects did not show a consistent pattern. The results suggest that the consistency between ideal standards and perceived partner attributes has a non-linear association with acceptance and relationship satisfaction, although the results were more conclusive for mean-level match.

  5. On central ideals of finitely generated binary (-1,1)-algebras

    International Nuclear Information System (INIS)

    Pchelintsev, S V

    2002-01-01

    In 1975 the author proved that the centre of a free finitely generated (-1,1)-algebra contains a non-zero ideal of the whole algebra. Filippov proved that in a free alternative algebra of rank ≥4 there exists a trivial ideal contained in the associative centre. Il'tyakov established that the associative nucleus of a free alternative algebra of rank 3 coincides with the ideal of identities of the Cayley-Dickson algebra. In the present paper the above-mentioned theorem of the author is extended to free finitely generated binary (-1,1)-algebras. Theorem. The centre of a free finitely generated binary (-1,1)-algebra of rank ≥3 over a field of characteristic distinct from 2 and 3 contains a non-zero ideal of the whole algebra. As a by-product, we shall prove that the T-ideal generated by the function (z,x,(x,x,y)) in a free binary (-1,1)-algebra of finite rank is soluble. We deduce from this that the basis rank of the variety of binary (-1,1)-algebras is infinite

  6. Interventions for preventing lower limb soft-tissue running injuries.

    Science.gov (United States)

    Yeung, Simon S; Yeung, Ella W; Gillespie, Lesley D

    2011-07-06

    Overuse soft-tissue injuries occur frequently in runners. Stretching exercises, modification of training schedules, and the use of protective devices such as braces and insoles are often advocated for prevention. This is an update of a review first published in 2001. To assess the effects of interventions for preventing lower limb soft-tissue running injuries. We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (March 2011); The Cochrane Library 2010, Issue 4; MEDLINE (1966 to January 2011); EMBASE (1980 to January 2011); and international trial registries (17 January 2011). Randomised or quasi-randomised trials evaluating interventions to prevent lower limb soft-tissue running injuries. Two authors independently assessed risk of bias (relating to sequence generation, allocation concealment, blinding, incomplete outcome data) and extracted data. Data were adjusted for clustering if necessary and pooled using the fixed-effect model when appropriate. We included 25 trials (30,252 participants). Participants were military recruits (19 trials), runners from the general population (three trials), soccer referees (one trial), and prisoners (two trials). The interventions tested in the included trials fell into four main preventive strategies: exercises, modification of training schedules, use of orthoses, and footwear and socks. All 25 included trials were judged as 'unclear' or 'high' risk of bias for at least one of the four domains listed above.We found no evidence that stretching reduces lower limb soft-tissue injuries (6 trials; 5130 participants; risk ratio [RR] 0.85, 95% confidence interval [95% CI] 0.65 to 1.12). As with all non-significant results, this is compatible with either a reduction or an increase in soft-tissue injuries. We found no evidence to support a training regimen of conditioning exercises to improve strength, flexibility and coordination (one trial; 1020 participants; RR 1.20, 95% CI 0.77 to 1.87).We found no

  7. A National Strategy to Develop Pragmatic Clinical Trials Infrastructure

    Science.gov (United States)

    Guise, Jeanne‐Marie; Dolor, Rowena J.; Meissner, Paul; Tunis, Sean; Krishnan, Jerry A.; Pace, Wilson D.; Saltz, Joel; Hersh, William R.; Michener, Lloyd; Carey, Timothy S.

    2014-01-01

    Abstract An important challenge in comparative effectiveness research is the lack of infrastructure to support pragmatic clinical trials, which compare interventions in usual practice settings and subjects. These trials present challenges that differ from those of classical efficacy trials, which are conducted under ideal circumstances, in patients selected for their suitability, and with highly controlled protocols. In 2012, we launched a 1‐year learning network to identify high‐priority pragmatic clinical trials and to deploy research infrastructure through the NIH Clinical and Translational Science Awards Consortium that could be used to launch and sustain them. The network and infrastructure were initiated as a learning ground and shared resource for investigators and communities interested in developing pragmatic clinical trials. We followed a three‐stage process of developing the network, prioritizing proposed trials, and implementing learning exercises that culminated in a 1‐day network meeting at the end of the year. The year‐long project resulted in five recommendations related to developing the network, enhancing community engagement, addressing regulatory challenges, advancing information technology, and developing research methods. The recommendations can be implemented within 24 months and are designed to lead toward a sustained national infrastructure for pragmatic trials. PMID:24472114

  8. A social-eco-democrat between ideals and reality

    Directory of Open Access Journals (Sweden)

    Đurić Jelena

    2010-01-01

    Full Text Available The challenge of discovering what is generally important vis-à-vis human being, through dealing with seemingly local topics, was the ideal of a late Serbian philosopher, ethicist and social theorist Prof. Dr. Svetozar Stojanović, the ideal that he, by his own self-understanding, was persistently explored. The rediscovery of his world-view initiated by his recent passing, has a potential to arouse momentous thinking on the principles of identity transformation.

  9. Social Network Project for IDEAL in CS5604

    OpenAIRE

    Harb, Islam; Jin, Yilong; Cedeno, Vanessa; Mallampati, Sai Ravi Kiran; Bulusu, Bhaskara Srinivasa Bharadwaj

    2015-01-01

    The IDEAL (Integrated Digital Event Archiving and Library) project involves VT faculty, staff, and students, along with collaborators around the world, in archiving important events and integrating the digital library, and archiving approaches to support the Research and Development related to important events. An objective of the CS5604 (Information Retrieval), Spring 2015 course, was to build a state-of-the-art information retrieval system, in support of the IDEAL project. Students were di...

  10. Lectures on the asymptotic theory of ideals

    CERN Document Server

    Rees, D

    1988-01-01

    In this book Professor Rees introduces and proves some of the main results of the asymptotic theory of ideals. The author's aim is to prove his Valuation Theorem, Strong Valuation Theorem, and Degree Formula, and to develop their consequences. The last part of the book is devoted to mixed multiplicities. Here the author develops his theory of general elements of ideals and gives a proof of a generalised degree formula. The reader is assumed to be familiar with basic commutative algebra, as covered in the standard texts, but the presentation is suitable for advanced graduate students. The work

  11. Wind energy: an application of Bernoulli's theorem generalized to isentropic flow of ideal gases

    International Nuclear Information System (INIS)

    De Luca, R; Desideri, P

    2013-01-01

    By considering the extension of Bernoulli's theorem to the case of the isentropic flow of ideal gases we conceive a small-scale wind–energy system able to work in the presence of low wind velocities in any direction. The flow of air inside a hyperbolically shaped pipe is studied using elementary physics concepts. The results obtained show that wind velocity in the system increases for decreasing cross-sectional areas, allowing a lower cut-in wind speed and an increase in the annual energy production of the device. (paper)

  12. An ideal job.

    Science.gov (United States)

    Leonard, Kurt J

    2012-01-01

    A brief personal history illustrates how fortunate I was to have stumbled into a career in plant pathology, which turned out to be the ideal job for me. Several of the people who steered me or facilitated my development in research on plant diseases are mentioned. Starting with my PhD research, I have had the good fortune to indulge a career-long fascination with epidemiology and genetics of disease resistance in plants, particularly coevolution of gene-for-gene host-pathogen systems. I hope that my example may inspire others of like minds to consider a research career in plant pathology.

  13. Study related to the generation of the conditional intensities of ideal Bose-gas

    International Nuclear Information System (INIS)

    Al-Oklah, H.

    2007-01-01

    In this paper, we will answer on the following question: Are there any conditions on the chemical potential and temperature of an ideal BOSE gas when generating the conditional intensities of ideal Bose-gas, and will the position distribution of the ideal Bose-gas be a Gibbs-process. The study shows that there should be no conditions on the chemical potential and thermodynamical temperature of an ideal BOSE gas when we generate the conditional intensities of ideal Bose-gas except that the fundamental conditions, the chemical potential is negative and the inverse temperature is positive. Thus the position distribution of the ideal Bose-gas may only be a Gibbs-process, in the special case when the thermodynamical temperature of the ideal BOSE gas tends to the absolute zero. (author)

  14. Ideal kingship in the late medieval world: The Ottoman case

    OpenAIRE

    Yelçe, Zeynep Nevin; Yelce, Zeynep Nevin

    2003-01-01

    The aim of this study is to examine the characteristics of the ideal ruler as seen through the eyes of the members of late medieval societies. Throughout the study, main features attributed to the ideal ruler in various cultures have been pursued. Comparing the concepts and attributes apparent in these cultures, it has become possible to talk about a single ideal of kingship as far as the "Christian" and "Muslim" realms of the late medieval era is concerned. The early Ottoman enterprise has b...

  15. Clinical Trials

    Medline Plus

    Full Text Available ... women and that are ethnically diverse. Children also need clinical trials that focus on them, as medical ... often differ for children. For example, children may need lower doses of certain medicines or smaller medical ...

  16. Prevention of Lower Extremity Injuries in Basketball

    Science.gov (United States)

    Taylor, Jeffrey B.; Ford, Kevin R.; Nguyen, Anh-Dung; Terry, Lauren N.; Hegedus, Eric J.

    2015-01-01

    Context: Lower extremity injuries are common in basketball, yet it is unclear how prophylactic interventions affect lower extremity injury incidence rates. Objective: To analyze the effectiveness of current lower extremity injury prevention programs in basketball athletes, focusing on injury rates of (1) general lower extremity injuries, (2) ankle sprains, and (3) anterior cruciate ligament (ACL) tears. Data Sources: PubMed, MEDLINE, CINAHL, SPORTDiscus, and the Cochrane Register of Controlled Trials were searched in January 2015. Study Selection: Studies were included if they were randomized controlled or prospective cohort trials, contained a population of competitive basketball athletes, and reported lower extremity injury incidence rates specific to basketball players. In total, 426 individual studies were identified. Of these, 9 met the inclusion criteria. One other study was found during a hand search of the literature, resulting in 10 total studies included in this meta-analysis. Study Design: Systematic review and meta-analysis. Level of Evidence: Level 2. Data Extraction: Details of the intervention (eg, neuromuscular vs external support), size of control and intervention groups, and number of injuries in each group were extracted from each study. Injury data were classified into 3 groups based on the anatomic diagnosis reported (general lower extremity injury, ankle sprain, ACL rupture). Results: Meta-analyses were performed independently for each injury classification. Results indicate that prophylactic programs significantly reduced the incidence of general lower extremity injuries (odds ratio [OR], 0.69; 95% CI, 0.57-0.85; P basketball athletes. Conclusion: In basketball players, prophylactic programs may be effective in reducing the risk of general lower extremity injuries and ankle sprains, yet not ACL injuries. PMID:26502412

  17. The Association of Ideal Cardiovascular Health and Atherogenic Index of Plasma in Rural Population: A Cross-Sectional Study from Northeast China.

    Science.gov (United States)

    Chang, Ye; Li, Yuan; Guo, Xiaofan; Dai, Dongxue; Sun, Yingxian

    2016-10-19

    In 2010, the American Heart Association has proposed a new concept "ideal cardiovascular health" (CVH) based on seven CVH metrics: smoking, body mass index, physical activity, diet score, total cholesterol, blood pressure, and fasting plasma glucose. We aimed to determine the association of CVH with atherogenic index of plasma (AIP), a strong marker for atherosclerosis (AS). This cross-sectional study was conducted in the rural areas of northeast China and 11,113 middle-aged subjects were enrolled. Seven CVH metrics were classified into ideal, intermediate, and poor groups. AIP was calculated as log (TG/HDL) (triglycerides/high-density lipoprotein cholesterol). AIP > 0.21 was classified into the high AIP group and served as dependent variable. All seven CVH metrics were correlated with AIP. A gradient relationship between the number of poor CVH metrics and the prevalence of high AIP existed. Log binomial regression analysis showed that compared to those with five to seven ideal CVH metrics, individuals with four, three, two, one, and no ideal CVH metrics had 1.67, 2.66, 4.00, 5.30 and 6.50 times higher prevalence for high AIP. The subjects with poor CVH status had 2.73 times higher prevalence for high AIP. We found an inversely gradient relationship between the number of ideal CVH metrics and lower prevalence of high AIP.

  18. Low-Dose Creatine Supplementation Lowers Plasma Guanidinoacetate, but Not Plasma Homocysteine, in a Double-Blind, Randomized, Placebo-Controlled Trial.

    Science.gov (United States)

    Peters, Brandilyn A; Hall, Megan N; Liu, Xinhua; Parvez, Faruque; Siddique, Abu B; Shahriar, Hasan; Uddin, Mohammad Nasir; Islam, Tariqul; Ilievski, Vesna; Graziano, Joseph H; Gamble, Mary V

    2015-10-01

    Creatine synthesis from guanidinoacetate consumes ~50% of s-adenosylmethionine (SAM)-derived methyl groups, accounting for an equivalent proportion of s-adenosylhomocysteine (SAH) and total homocysteine (tHcys) synthesis. Dietary creatine inhibits the synthesis of guanidinoacetate, thereby lowering plasma tHcys in rats. We tested the hypotheses that creatine supplementation lowers plasma guanidinoacetate, increases blood SAM, lowers blood SAH, and lowers plasma tHcys. Bangladeshi adults were randomly assigned to receive 1 of 4 treatments for 12 wk: placebo (n = 101), 3 g/d creatine (Cr; n = 101), 400 μg/d folic acid (FA; n = 153), or 3 g/d creatine plus 400 μg/d folic acid (Cr+FA; n = 103). The outcomes of plasma guanidinoacetate and tHcys, as well as whole blood SAM and SAH, were analyzed at baseline and week 12 by HPLC. Treatment effects of creatine supplementation were examined with the use of the group comparisons of Cr vs. placebo and Cr+FA vs. FA. Plasma guanidinoacetate declined by 10.6% (95% CI: 4.9, 15.9) in the Cr group while increasing nonsignificantly in the placebo group (3.7%; 95% CI: -0.8, 8.5) (Pgroup difference = 0.0002). Similarly, plasma guanidinoacetate declined by 9.0% (95% CI: 3.4, 14.2) in the Cr+FA group while increasing in the FA group (7.0%; 95% CI: 2.0, 12.2) (Pgroup difference creatine supplementation downregulates endogenous creatine synthesis, this may not on average lower plasma tHcys in humans. However, tHcys did decrease in those participants who experienced a decline in plasma guanidinoacetate while receiving creatine plus folic acid supplementation. This trial was registered at clinicaltrials.gov as NCT01050556. © 2015 American Society for Nutrition.

  19. Reported Effects of Masculine Ideals on Gay Men

    OpenAIRE

    Sánchez, Francisco J.; Greenberg, Stefanie T.; Liu, William Ming; Vilain, Eric

    2009-01-01

    This exploratory study used consensual qualitative research methodology (Hill et al., 2005) to analyze what gay men associate with masculinity and femininity, how they feel masculine ideals affect their self-image, and how masculine ideals affect their same-sex relationships. Written responses were collected from 547 self-identified gay men in the U.S. via an Internet-based survey. Findings supported previous reports that perceptions of gender roles among gay men appear based on masculine and...

  20. The electrical conductivity of a weakly non-ideal, dense plasma

    NARCIS (Netherlands)

    Rosado, R.J.; Leclair, J.; Schram, D.C.

    1977-01-01

    The electrical conductance of a non-ideal plasma was measured and compared with Spitzer's formula for ideal plasmas and a correction to this formula proposed by Rovinskii. The measured conductance proved to agree better with the Spitzer result

  1. Ideal clocks—a convenient fiction

    International Nuclear Information System (INIS)

    Lorek, Krzysztof; Dragan, Andrzej; Louko, Jorma

    2015-01-01

    We show that no device built according to the rules of quantum field theory can measure proper time along its path. Highly accelerated quantum clocks experience the Unruh effect, which inevitably influences their time rate. This contradicts the concept of an ideal clock, whose rate should only depend on the instantaneous velocity. (paper)

  2. Neutrosophic Crisp Points & Neutrosophic Crisp Ideals

    Directory of Open Access Journals (Sweden)

    A. A. Salama

    2013-03-01

    Full Text Available The purpose of this paper is to define the so called "neutrosophic crisp points" and "neutrosophic crisp ideals", and obtain their fundamental properties. Possible application to GIS topology rules are touched upon.

  3. The direct effect of thin ideal focused adult television on young girls' ideal body figure

    NARCIS (Netherlands)

    Anschutz, Doeschka J; Spruijt-Metz, Donna; van Strien, Tatjana; Engels, Rutger C M E

    The present study tested the direct effect of watching thin-ideal focused television aimed at (young) adults on body dissatisfaction in preadolescent girls (9-12 years old). A within-subject design was used in which the girls (N=60) were tested three times. They watched three movie clips in random

  4. Gravity wave generation from jets and fronts: idealized and real-case simulations

    Science.gov (United States)

    Plougonven, Riwal; Arsac, Antonin; Hertzog, Albert; Guez, Lionel; Vial, François

    2010-05-01

    The generation of gravity waves from jets and fronts remains an outstanding issue in the dynamics of the atmosphere. It is important to explain and quantify this emission because of the several impacts of these waves, in particular the induced momentum fluxes towards the middle atmosphere, and their contribution to turbulence and mixing, e.g. in the region of the tropopause. Yet, the mechanisms at the origin of these waves have been difficult to identify, the fundamental reason for this being the separation between the time scales of balanced motions and gravity waves. Recent simulations of idealized baroclinic life cycles and of dipoles have provided insights into the mechanisms determining the characteristics and the amplitude of gravity waves emitted by jets. It has been shown in particular that the environmental strain and shear play a crucial role in determining the characteristics and location of the emitted waves, emphasizing jet exit regions for the appearance of coherent low-frequency waves. It has also been shown how advection of relatively small-scales allow to overcome the separation of time scales alluded to above. Recent results, remaining open questions and ongoing work on these idealized simulations will be briefly summarized. Nevertheless, unavoidable shortcomings of such idealized simulations include the sensitivity of the emitted waves to model setup (resolution, diffusion, parameterizations) and uncertainty regarding the realism of this aspect of the simulations. Hence, it is necessary to compare simulations with observations in order to assess their relevance. Such comparison has been undertaken using the dataset from the Vorcore campaign (Sept. 2005 - Feb. 2006, Hertzog, J. Atmos. Ocean. Techno. 2007) during which 27 superpressure balloons drifted as quasi-Lagrangian tracers in the lower stratosphere above Antarctica and the Southern Ocean. High-resolution simulations (dx = 20 km) have been carried out using the Weather Research and Forecast

  5. A Unified Theory of Non-Ideal Gas Lattice Boltzmann Models

    Science.gov (United States)

    Luo, Li-Shi

    1998-01-01

    A non-ideal gas lattice Boltzmann model is directly derived, in an a priori fashion, from the Enskog equation for dense gases. The model is rigorously obtained by a systematic procedure to discretize the Enskog equation (in the presence of an external force) in both phase space and time. The lattice Boltzmann model derived here is thermodynamically consistent and is free of the defects which exist in previous lattice Boltzmann models for non-ideal gases. The existing lattice Boltzmann models for non-ideal gases are analyzed and compared with the model derived here.

  6. Effect of compositional heterogeneity on dissolution of non-ideal LNAPL mixtures

    Science.gov (United States)

    Vasudevan, M.; Johnston, C. D.; Bastow, T. P.; Lekmine, G.; Rayner, J. L.; Nambi, I. M.; Suresh Kumar, G.; Ravi Krishna, R.; Davis, G. B.

    2016-11-01

    The extent of dissolution of petroleum hydrocarbon fuels into groundwater depends greatly on fuel composition. Petroleum fuels can consist of thousands of compounds creating different interactions within the non-aqueous phase liquid (NAPL), thereby affecting the relative dissolution of the components and hence a groundwater plume's composition over long periods. Laboratory experiments were conducted to study the variability in the effective solubilities and activity coefficients for common constituents of gasoline fuels (benzene, toluene, p-xylene and 1,2,4-trimethylbenzene) (BTX) in matrices with an extreme range of molar volumes and chemical affinities. Four synthetic mixtures were investigated comprising BTX with the bulk of the NAPL mixtures made up of either, ethylbenzene (an aromatic like BTX with similar molar volume); 1,3,5-trimethylbenzene (an aromatic with a greater molar volume); n-hexane (an aliphatic with a low molar volume); and n-decane (an aliphatic with a high molar volume). Equilibrium solubility values for the constituents were under-predicted by Raoult's law by up to 30% (higher experimental concentrations) for the mixture with n-hexane as a filler and over-predicted by up to 12% (lower experimental concentrations) for the aromatic mixtures with ethylbenzene and 1,3,5-trimethylbenzene as fillers. Application of PP-LFER (poly-parameter linear free energy relationship) model for non-ideal mixtures also resulted in poor correlation between experimentally measured and predicted concentrations, indicating that differences in chemical affinities can be the major cause of deviation from ideal behavior. Synthetic mixtures were compared with the dissolution behavior of fresh and naturally weathered unleaded gasoline. The presence of lighter aliphatic components in the gasoline had a profound effect on estimating effective solubility due to chemical affinity differences (estimated at 0.0055 per percentage increase in the molar proportion of aliphatic) as

  7. Amino acids fortification of low-protein diet for broilers under tropical climate: ideal essential amino acids profile

    Directory of Open Access Journals (Sweden)

    Elmutaz Atta Awad

    2014-05-01

    Full Text Available A three-week trial was conducted to determine the effect of lowering dietary protein level (DPL with optimal amino acid (AA profile on growth performance, blood metabolites, and relative weights of abdominal fat and internal organs in broiler chickens raised under tropical hot and humid environment. Five isocaloric (3023 metabolisable energy/kg starter (1-21 days experimental diets were formulated in a gradual crude protein (CP decline from 22.2 (control to 16.2% by 1.5% interval. All diets were meeting or exceeding National Research Council recommendations except CP and metabolisable energy. The formulations were also adjusted to contain 1.1 digestible Lys to meet the ideal AA ratios concept. Body weights (BW, weight gains (WG, feed intake and feed conversion ratio of groups with 19.2, 20.7 and 22.2% DPL were not significantly different. However, BW and WG suppressed (P<0.05 with 16.2 and 17.7% DPL. Feeding the 16.2% CP diet significantly reduced serum total protein and uric acid, but increased serum triglyceride (P<0.05. Moreover, relative heart weights increased (P<0.05 but no changes occurred in liver and abdominal fat weights in chicks with 16.2% DPL. In summary, CP of broilers starter (1-21 days diet can be reduced till 19.2% with essential AA fortification and without any adverse effect on growth performance under the hot, humid tropics.

  8. Nonlinear transport properties of non-ideal systems

    International Nuclear Information System (INIS)

    Pavlov, G A

    2009-01-01

    The theory of nonlinear transport is elaborated to determine the Burnett transport properties of non-ideal multi-element plasma and neutral systems. The procedure for the comparison of the phenomenological conservation equations of a continuous dense medium and the microscopic equations for dynamical variable operators is used for the definition of these properties. The Mori algorithm is developed to derive the equations of motion of dynamical value operators of a non-ideal system in the form of the generalized nonlinear Langevin equations. In consequence, the microscopic expressions of transport coefficients corresponding to second-order thermal disturbances (temperature, mass velocity, etc) have been found in the long wavelength and low frequency limits

  9. Compliance to the prescribed dose and overall treatment time in five randomized clinical trials of altered fractionation in radiotherapy for head-and-neck carcinomas

    International Nuclear Information System (INIS)

    Khalil, Azza A.; Bentzen, Soeren M.; Bernier, Jacques; Saunders, Michele I.; Horiot, Jean-Claude; Bogaert, Walter van den; Cummings, Bernard J.; Dische, Stanley

    2003-01-01

    Purpose: To investigate compliance to the prescribed dose-fractionation schedule in five randomized controlled trials of altered fractionation in radiotherapy for head-and-neck carcinoma. Methods and Materials: Individual patient data from 2566 patients participating in the European Organization for Research and Treatment of Cancer (EORTC) 22791, EORTC 22811, EORTC 22851, Princess Margaret Hospital (PMH), and continuous hyperfractionated accelerated radiotherapy (CHART) head-and-neck trials were merged in the fractionation IMPACT (Intergroup Merger of Patient data from Altered or Conventional Treatment schedules) study database. The ideal treatment time was defined as the minimum time required to deliver a prescribed schedule. Compliance to the prescribed overall treatment time was quantified as the difference between the actual and the ideal overall time. An overall measure of compliance in an individual patient, the total dose lost (TDL), was calculated as the dose lost due to prolongation of therapy (assuming a D prolif of 0.64 Gy/day) plus the difference between the prescribed and the actual dose given. Results: The time in excess of the ideal ranged up to 97 days (average 3.9 days), and 25% of the patients had delays of 6 days or more. World Health Organization (WHO) performance status and nodal stage had a significant effect on TDL. TDL was significantly higher in the conventional than in the altered arm of the EORTC 22851 and CHART trials. In the PMH trial, TDL was significantly higher in the hyperfractionation than in the conventional arm. Centers participating in the three EORTC trials varied significantly in their compliance. There was a significant improvement in compliance in patients treated more recently. Conclusions: Even in randomized controlled trials, compliance to the prescribed radiation therapy schedule may be relatively poor, especially after conventional fractionation. This affects the interpretation of the outcome of these trials

  10. Delivering ideal employee experiences.

    Science.gov (United States)

    Weiss, Marjorie D; Tyink, Steve; Kubiak, Curt

    2009-05-01

    Employee-centric strategies have moved from employee satisfaction and brand awareness to employee "affinity" or "attachment." In today's marketplace, occupational health nurses understand that differentiation (i.e., the perception of uniqueness) is the direct result of superior employee interactions, which lead to better employee care, enduring employee relationships, loyal employees, and satisfied employers. What drives employees to occupational health nurse attachment? The answer is a passion for rising above the competition to create ideal employee experiences.

  11. Robotic kidney transplantation with regional hypothermia: evolution of a novel procedure utilizing the IDEAL guidelines (IDEAL phase 0 and 1).

    Science.gov (United States)

    Menon, Mani; Abaza, Ronney; Sood, Akshay; Ahlawat, Rajesh; Ghani, Khurshid R; Jeong, Wooju; Kher, Vijay; Kumar, Ramesh K; Bhandari, Mahendra

    2014-05-01

    Surgical innovation is essential for progress of surgical science, but its implementation comes with potential harms during the learning phase. The Balliol Collaboration has recommended a set of guidelines (Innovation, Development, Exploration, Assessment, Long-term study [IDEAL]) that permit innovation while minimizing complications. To utilize the IDEAL model of surgical innovation in the development of a novel surgical technique, robotic kidney transplantation (RKT) with regional hypothermia, and describe the process of discovery and development. Phase 0 (simulation) studies included the establishment of techniques for pelvic cooling, graft placement in a robotic prostatectomy model, and simulation of the RKT procedure in a cadaveric model. Phase 1 (innovation) studies began in January 2013 and involved treatment of a highly selective small group of patients (n=7), using the principles utilized in the phase 0 studies, at a tertiary referral center. IDEAL model implementation in the development of RKT with regional hypothermia. For phase 0 studies, the outcomes evaluated included pelvic and body temperature measurements, and technical feasibility assessment. The primary outcome during phase 1 was post-transplant graft function. Other outcomes measured were operative and ischemic times, perioperative complications, and intracorporeal graft surface temperature. Phase 0 (simulation phase): Pelvic cooling to 15-20(o)C was achieved reproducibly. Using the surgical approach developed for robotic radical prostatectomy, vascular and ureterovesical anastomoses could be done without redocking the robot. Phase 1 (innovation phase): All patients underwent live-donor RKT in the lithotomy position. All grafts functioned immediately. Mean console, anastomotic, and warm ischemia times were 154 min, 29 min, and 2 min, respectively. One patient was re-explored on postoperative day 1. Adherence to the IDEAL guidelines put forth by the Balliol Collaboration provided a practical

  12. The positive-entropy constraint for the classical ideal gas

    International Nuclear Information System (INIS)

    Ciccariello, Salvino

    2004-01-01

    The problem of determining the state parameters' sub-domain where the behaviour of the classical ideal gas approximates that of the Bose and Fermi ideal gases is tutorially discussed. The entropy of any quantum system being always positive, the classical approximation can only be satisfactory within the parameters' sub-domain where the classical entropy turns out to be positive. We show that the sub-domain determined by this condition is close to that where de Broglie's thermal wavelength is smaller than the mean interparticle distance. The exact determination of the state parameters' region, where the particle number density, the grand potential and the entropy of quantum ideal gases differ from those of the classical gas less than a specified quantity, is also illustrated

  13. The Limits of Autonomy: Ideals in Care for People with Learning Disabilities

    NARCIS (Netherlands)

    Pols, Jeannette; Althoff, Brigitte; Bransen, Els

    2017-01-01

    In the Netherlands, autonomy is a key ideal in visions of care for people with learning disability. This ideal can lead to tension when clients, in the opinion of their caregivers, overuse alcohol or drugs. In this article, we analyze how professional caregivers understand the ideal of autonomy in

  14. Caste and Choice: The Influence of Developmental Idealism on Marriage Behavior

    Science.gov (United States)

    Allendorf, Keera; Thornton, Arland

    2015-01-01

    Is young people’s marriage behavior determined by their socioeconomic characteristics or their endorsement of developmental idealism? This article addresses this question using a unique, longitudinal data set from Nepal and provides the first individual-level test of developmental idealism theory. We find that unmarried individuals with greater endorsement of developmental idealism in 2008 were more likely by 2012 to choose their own spouse, including a spouse of a different caste, rather than have an arranged marriage. Those with salaried work experience were also less likely to have arranged marriages, but urban proximity and education were not significant. We conclude that both developmental idealism and socioeconomic characteristics influence marriage and their influences are largely independent. PMID:26430712

  15. Reported Effects of Masculine Ideals on Gay Men.

    Science.gov (United States)

    Sánchez, Francisco J; Greenberg, Stefanie T; Liu, William Ming; Vilain, Eric

    2009-01-01

    This exploratory study used consensual qualitative research methodology (Hill et al., 2005) to analyze what gay men associate with masculinity and femininity, how they feel masculine ideals affect their self-image, and how masculine ideals affect their same-sex relationships. Written responses were collected from 547 self-identified gay men in the U.S. via an Internet-based survey. Findings supported previous reports that perceptions of gender roles among gay men appear based on masculine and feminine stereotypes. Additionally, more adverse versus positive effects on self-image and same-sex romantic relationships were reported including difficulty being emotional and affectionate, pressure to be physically attractive, and pressure to appear masculine in order to be accepted by society and to be seen as desirable by other gay men. While research on gay men's experience with masculinity continues, psychologists should consider the possible influence of traditional masculine ideals when conceptualizing their gay male clients.

  16. Some Results on the Intersection Graphs of Ideals of Rings

    International Nuclear Information System (INIS)

    Akbari, S.; Nikandish, R.; Nikmehr, M.J.

    2010-08-01

    Let R be a ring with unity and I(R)* be the set of all non-trivial left ideals of R. The intersection graph of ideals of R, denoted by G(R), is a graph with the vertex set I(R)* and two distinct vertices I and J are adjacent if and only if I intersection J ≠ 0. In this paper, we study some connections between the graph-theoretic properties of this graph and some algebraic properties of rings. We characterize all rings whose intersection graphs of ideals are not connected. Also we determine all rings whose clique number of the intersection graphs of ideals are finite. Among other results, it is shown that for every ring, if the clique number of G(R) is finite, then the chromatic number is finite too and if R is a reduced ring both are equal. (author)

  17. Numerical study of the axisymmetric ideal MHD stability of Extrap

    International Nuclear Information System (INIS)

    Benda, M.

    1993-04-01

    A numerical study of the free-boundary axisymmetric (n=0) ideal magnetohydrodynamical (MHD) motions of the Extrap device is presented. The dependence of stability on current profiles in the plasma and currents in the external conductors is investigated. Results are shown for linear growth-rates and nonlinear saturation amplitudes and their dependence on plasma radius as well as on the conducting shell radius. A method combined of two different algorithms has been developed and tested. The interior region of the plasma is simulated by means of a Lagrangian Finite Element Method (FEM) for ideal magnetohydrodynamics, The method is based on a nonlinear radiation principle for the Lagrangian description of ideal MHD. The Boundary Element Method (BEM) is used together with the Lagrangian FEM to simulate nonlinear motion of an ideal MHD plasma behaviour in a vacuum region under the influence of external magnetic fields. 31 refs

  18. Sclerotherapy for Reticular Veins in the Lower Limbs: A Triple-Blind Randomized Clinical Trial.

    Science.gov (United States)

    Bertanha, Matheus; Jaldin, Rodrigo Gibin; Moura, Regina; Pimenta, Rafael Elias Farres; Mariúba, Jamil Victor de Oliveira; Lúcio Filho, Carlos Eduardo Pinheiro; Alcantara, Giovana Piteri; Padovani, Carlos Roberto; Yoshida, Winston Bonetti; Sobreira, Marcone Lima

    2017-12-01

    Reticular veins are subdermal veins located in the lower limbs and are mainly associated with aesthetic complaints. Although sclerotherapy is the treatment of choice for reticular veins in the lower limbs, no consensus has been reached regarding to the optimal sclerosant. To compare the efficacy and safety of 2 sclerosants used to treat reticular veins: 0.2% polidocanol diluted in 70% hypertonic glucose (HG) (group 1) vs 75% HG alone (group 2). Prospective, randomized, triple-blind, controlled, parallel-group clinical trial with patients randomly assigned in a 1:1 ratio between the 2 treatment groups from March through December 2014, with 2 months' follow-up. The study was conducted in a single academic medical center. Eligible participants were all women, aged 18 to 69 years, who had at least 1 reticular vein with a minimum length of 10 cm in 1 of their lower limbs. The patients underwent sclerotherapy in a single intervention with either 0.2% polidocanol plus 70% HG or 75% HG alone to eliminate reticular veins. The primary efficacy end point was the disappearance of the reticular veins within 60 days after treatment with sclerotherapy. The reticular veins were measured on images obtained before treatment and after treatment using ImageJ software. Safety outcomes were analyzed immediately after treatment and 7 days and 60 days after treatment and included serious adverse events (eg, deep vein thrombosis and systemic complications) and minor adverse events (eg, pigmentation, edema, telangiectatic matting, and hematomas). Ninety-three women completed the study, median (interquartile range) age 43.0 (24.0-61.0) years for group 1 and 41.0 (27.0-62.0) years for group 2. Sclerotherapy with 0.2% polidocanol plus 70% HG was significantly more effective than with 75% HG alone in eliminating reticular veins from the treated area (95.17% vs 85.40%; P vein pigmentation length for group 1 and 7.09% for group 2, with no significant difference between the groups (P = .09

  19. Recent perspectives on the role of nutraceuticals as cholesterol-lowering agents.

    Science.gov (United States)

    Ward, Natalie; Sahebkar, Amirhossein; Banach, Maciej; Watts, Gerald

    2017-12-01

    Reduction in circulating cholesterol is an important step in lowering cardiovascular risk. Although statins are the most frequently prescribed cholesterol-lowering medication, there remains a significant portion of patients who require alternative treatment options. Nutraceuticals are increasingly popular as cholesterol-lowering agents. Despite the lack of long-term trials evaluating their use on cardiovascular endpoints and mortality, several studies have demonstrated their potential cholesterol-lowering effects. The purpose of this review is to provide an update on the role of nutraceuticals as cholesterol-lowering agents. The present review will focus on individual nutraceutical compounds, which have shown modest cholesterol-lowering abilities, as well as combination nutraceuticals, which may offer potential additive and/or synergistic effects. Berberine, red yeast rice, and plant sterols have moderate potential as cholesterol-lowering agents. Combination nutraceuticals, including the proprietary formulation, Armolipid Plus, appear to confer additional benefit on plasma lipid profiles, even when taken with statins and other agents. Although robust, long-term clinical trials to examine the effects of nutraceuticals on clinical outcomes are still required, their cholesterol-lowering ability, together with their reported tolerance and safety, offer a pragmatic option for lowering plasma cholesterol levels.

  20. Structural arrest in an ideal gas.

    Science.gov (United States)

    van Ketel, Willem; Das, Chinmay; Frenkel, Daan

    2005-04-08

    We report a molecular dynamics study of a simple model system that has the static properties of an ideal gas, yet exhibits nontrivial "glassy" dynamics behavior at high densities. The constituent molecules of this system are constructs of three infinitely thin hard rods of length L, rigidly joined at their midpoints. The crosses have random but fixed orientation. The static properties of this system are those of an ideal gas, and its collision frequency can be computed analytically. For number densities NL(3)/V>1, the single-particle diffusivity goes to zero. As the system is completely structureless, standard mode-coupling theory cannot describe the observed structural arrest. Nevertheless, the system exhibits many dynamical features that appear to be mode-coupling-like. All high-density incoherent intermediate scattering functions collapse onto master curves that depend only on the wave vector.

  1. Directions for new developments on statistical design and analysis of small population group trials.

    Science.gov (United States)

    Hilgers, Ralf-Dieter; Roes, Kit; Stallard, Nigel

    2016-06-14

    Most statistical design and analysis methods for clinical trials have been developed and evaluated where at least several hundreds of patients could be recruited. These methods may not be suitable to evaluate therapies if the sample size is unavoidably small, which is usually termed by small populations. The specific sample size cut off, where the standard methods fail, needs to be investigated. In this paper, the authors present their view on new developments for design and analysis of clinical trials in small population groups, where conventional statistical methods may be inappropriate, e.g., because of lack of power or poor adherence to asymptotic approximations due to sample size restrictions. Following the EMA/CHMP guideline on clinical trials in small populations, we consider directions for new developments in the area of statistical methodology for design and analysis of small population clinical trials. We relate the findings to the research activities of three projects, Asterix, IDeAl, and InSPiRe, which have received funding since 2013 within the FP7-HEALTH-2013-INNOVATION-1 framework of the EU. As not all aspects of the wide research area of small population clinical trials can be addressed, we focus on areas where we feel advances are needed and feasible. The general framework of the EMA/CHMP guideline on small population clinical trials stimulates a number of research areas. These serve as the basis for the three projects, Asterix, IDeAl, and InSPiRe, which use various approaches to develop new statistical methodology for design and analysis of small population clinical trials. Small population clinical trials refer to trials with a limited number of patients. Small populations may result form rare diseases or specific subtypes of more common diseases. New statistical methodology needs to be tailored to these specific situations. The main results from the three projects will constitute a useful toolbox for improved design and analysis of small

  2. Idealism and realism in International Relations: an ontological debate

    Directory of Open Access Journals (Sweden)

    Vitor Ramon Fernandes

    2016-11-01

    Full Text Available The debate between realism and idealism continues to mark the discipline of International Relations. On the one hand, realism argues that international politics is a struggle for power and a quest for survival, which results in a condition of permanent conflict between States without any possibility of evolution or progress. On the other hand, idealism considers it possible to build a world of peaceful coexistence, prosperity and well-being, achieved through cooperation and based on values and aspirations shared by humans. The object of this article is to analyse the debate between idealism and realism, considering it as an ontological debate and taking into account the controversy it has generated. The argument presented here is that both realism and idealism are two responses to the creation and maintenance of international order, that is, how States relate in international society; however these responses are not mutually exclusive and can coexist in constant tension with one another. An analysis of internationalist thought of two authors, Hans Morgenthau and Raymond Aron, is also presented, which relates to how they are positioned in this debate as well as International Relations as a whole.

  3. Does lowering cholesterol have an impact on the progression of aortic stenosis?

    DEFF Research Database (Denmark)

    Greve, A.M.; Wachtell, K.

    2008-01-01

    reviews the pathophysiological mechanisms of calcific AS, reviews current clinical trials of statin use in aortic stenosis and reports on on-going trials, evaluating whether cholesterol lowering therapy can slow disease progression in different populations. Finally, we review if computerized tomography...

  4. Hybrid normed ideal perturbations of n-tuples of operators I

    Science.gov (United States)

    Voiculescu, Dan-Virgil

    2018-06-01

    In hybrid normed ideal perturbations of n-tuples of operators, the normed ideal is allowed to vary with the component operators. We begin extending to this setting the machinery we developed for normed ideal perturbations based on the modulus of quasicentral approximation and an adaptation of our non-commutative generalization of the Weyl-von Neumann theorem. For commuting n-tuples of hermitian operators, the modulus of quasicentral approximation remains essentially the same when Cn- is replaced by a hybrid n-tuple Cp1,…- , … , Cpn- , p1-1 + ⋯ + pn-1 = 1. The proof involves singular integrals of mixed homogeneity.

  5. Variational integration for ideal magnetohydrodynamics with built-in advection equations

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Yao; Burby, J. W.; Bhattacharjee, A. [Plasma Physics Laboratory, Princeton University, Princeton, New Jersey 08543 (United States); Qin, Hong [Plasma Physics Laboratory, Princeton University, Princeton, New Jersey 08543 (United States); Department of Modern Physics, University of Science and Technology of China, Hefei, Anhui 230026 (China)

    2014-10-15

    Newcomb's Lagrangian for ideal magnetohydrodynamics (MHD) in Lagrangian labeling is discretized using discrete exterior calculus. Variational integrators for ideal MHD are derived thereafter. Besides being symplectic and momentum-preserving, the schemes inherit built-in advection equations from Newcomb's formulation, and therefore avoid solving them and the accompanying error and dissipation. We implement the method in 2D and show that numerical reconnection does not take place when singular current sheets are present. We then apply it to studying the dynamics of the ideal coalescence instability with multiple islands. The relaxed equilibrium state with embedded current sheets is obtained numerically.

  6. Variational Integration for Ideal MHD with Built-in Advection Equations

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Yao [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Qin, Hong [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Burby, J. W. [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Bhattacharjee, A. [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States)

    2014-08-05

    Newcomb's Lagrangian for ideal MHD in Lagrangian labeling is discretized using discrete exterior calculus. Variational integrators for ideal MHD are derived thereafter. Besides being symplectic and momentum preserving, the schemes inherit built-in advection equations from Newcomb's formulation, and therefore avoid solving them and the accompanying error and dissipation. We implement the method in 2D and show that numerical reconnection does not take place when singular current sheets are present. We then apply it to studying the dynamics of the ideal coalescence instability with multiple islands. The relaxed equilibrium state with embedded current sheets is obtained numerically.

  7. Simulasi Tumbukan Partikel Gas Ideal Dengan Model Cellular Automata Dua Dimensi

    OpenAIRE

    Abdul Basid, Annisa Mujriati

    2010-01-01

    Telah dilakukan simulasi tumbukan partikel gas ideal dengan menggunakan  model cellular automata dua dimensi untuk memvisualisasikan tumbukan partikel gas ideal. Tumbukan partikel  disimulasikan  dengan  menggunakan  model  cellular  automata  dua  dimensi.  Di  dalam cellular automata, pergerakan partikel diatur dengan suatu aturan  yaitu aturan delapan tetangga yang merupakan aturan acak. Hasil program simulasi tumbukan partikel gas ideal dengan model cellular automata dua dimensi  mengguna...

  8. Idealness and similarity in goal-derived categories: a computational examination.

    Science.gov (United States)

    Voorspoels, Wouter; Storms, Gert; Vanpaemel, Wolf

    2013-02-01

    The finding that the typicality gradient in goal-derived categories is mainly driven by ideals rather than by exemplar similarity has stood uncontested for nearly three decades. Due to the rather rigid earlier implementations of similarity, a key question has remained--that is, whether a more flexible approach to similarity would alter the conclusions. In the present study, we evaluated whether a similarity-based approach that allows for dimensional weighting could account for findings in goal-derived categories. To this end, we compared a computational model of exemplar similarity (the generalized context model; Nosofsky, Journal of Experimental Psychology. General 115:39-57, 1986) and a computational model of ideal representation (the ideal-dimension model; Voorspoels, Vanpaemel, & Storms, Psychonomic Bulletin & Review 18:1006-114, 2011) in their accounts of exemplar typicality in ten goal-derived categories. In terms of both goodness-of-fit and generalizability, we found strong evidence for an ideal approach in nearly all categories. We conclude that focusing on a limited set of features is necessary but not sufficient to account for the observed typicality gradient. A second aspect of ideal representations--that is, that extreme rather than common, central-tendency values drive typicality--seems to be crucial.

  9. Personality traits and appearance-ideal internalization: Differential associations with body dissatisfaction and compulsive exercise.

    Science.gov (United States)

    Martin, Shelby J; Racine, Sarah E

    2017-12-01

    Thin-ideal internalization is a robust risk factor for body dissatisfaction and eating pathology. Conversely, athletic-ideal internalization is often unrelated to body dissatisfaction, but predicts compulsive exercise (i.e., rigid, rule-driven exercise that is continued despite adverse consequences). Distinct personality traits could relate to internalization of different appearance ideals, which may be associated with divergent eating disorder outcomes. Past research has shown that neuroticism is related to body dissatisfaction, whereas extraversion and conscientiousness have been associated with regular and problematic exercise. The current study examined associations among personality traits (i.e., neuroticism, extraversion, conscientiousness), appearance-ideal internalization (i.e., thin- and athletic-ideal), and eating disorder cognitions/behaviors (i.e., body dissatisfaction, compulsive exercise) among 531 college men and women. Moreover, we tested whether appearance-ideal internalization mediated the relationships between personality traits with body dissatisfaction and compulsive exercise. As expected, body dissatisfaction was positively related to neuroticism, and compulsive exercise was positively associated with extraversion. Thin-ideal internalization positively correlated with neuroticism, athletic-ideal internalization positively correlated with conscientiousness, and both thin- and athletic-ideal internalization were positively related to extraversion. After controlling for gender, body mass index, the other appearance-ideal internalization, and the remaining personality traits, the indirect effects of both neuroticism and extraversion on body dissatisfaction through thin-ideal internalization were significant. Extraversion and conscientiousness were indirectly related to compulsive exercise through athletic-ideal internalization, whereas the indirect effect of neuroticism was dependent on covariates. As such, personality traits may be related to

  10. Effects of long-term weekly iron and folic acid supplementation on lower genital tract infection - a double blind, randomised controlled trial in Burkina Faso.

    Science.gov (United States)

    Brabin, Loretta; Roberts, Stephen A; Gies, Sabine; Nelson, Andrew; Diallo, Salou; Stewart, Christopher J; Kazienga, Adama; Birtles, Julia; Ouedraogo, Sayouba; Claeys, Yves; Tinto, Halidou; d'Alessandro, Umberto; Faragher, E Brian; Brabin, Bernard

    2017-11-23

    Provision of routine iron supplements to prevent anaemia could increase the risk for lower genital tract infections as virulence of some pathogens depends on iron availability. This trial in Burkina Faso assessed whether weekly periconceptional iron supplementation increased the risk of lower genital tract infection in young non-pregnant and pregnant women. Genital tract infections were assessed within a double blind, controlled, non-inferiority trial of malaria risk among nulliparous women, randomised to receive either iron and folic acid or folic acid alone, weekly, under direct observation for 18 months. Women conceiving during this period entered the pregnancy cohort. End assessment (FIN) for women remaining non-pregnant was at 18 months. For the pregnancy cohort, end assessment was at the first scheduled antenatal visit (ANC1). Infection markers included Nugent scores for abnormal flora and bacterial vaginosis (BV), T. vaginalis PCR, vaginal microbiota, reported signs and symptoms, and antibiotic and anti-fungal prescriptions. Iron biomarkers were assessed at baseline, FIN and ANC1. Analysis compared outcomes by intention to treat and in iron replete/deficient categories. A total of 1954 women (mean 16.8 years) were followed and 478 (24.5%) became pregnant. Median supplement adherence was 79% (IQR 59-90%). Baseline BV prevalence was 12.3%. At FIN and ANC1 prevalence was 12.8% and 7.0%, respectively (P Iron-supplemented non-pregnant women received more antibiotic treatments for non-genital infections (P = 0.014; mainly gastrointestinal infections (P = 0.005), anti-fungal treatments for genital infections (P = 0.014) and analgesics (P = 0.008). Weekly iron did not significantly reduce iron deficiency prevalence. At baseline, iron-deficient women were more likely to have normal vaginal flora (P = 0.016). Periconceptional weekly iron supplementation of young women did not increase the risk of lower genital tract infections but did increase

  11. Thermodynamics of an ideal generalized gas: I. Thermodynamic laws.

    Science.gov (United States)

    Lavenda, B H

    2005-11-01

    The equations of state for an ideal relativistic, or generalized, gas, like an ideal quantum gas, are expressed in terms of power laws of the temperature. In contrast to an ideal classical gas, the internal energy is a function of volume at constant temperature, implying that the ideal generalized gas will show either attractive or repulsive interactions. This is a necessary condition in order that the third law be obeyed and for matter to have an electromagnetic origin. The transition from an ideal generalized to a classical gas occurs when the two independent solutions of the subsidiary equation to Lagrange's equation coalesce. The equation of state relating the pressure to the internal energy encompasses the full range of cosmological scenarios, from the radiation to the matter dominated universes and finally to the vacuum energy, enabling the coefficient of proportionality, analogous to the Grüeisen ratio, to be interpreted in terms of the degrees of freedom related to the temperature exponents of the internal energy and the absolute temperature expressed in terms of a power of the empirical temperature. The limit where these exponents merge is shown to be the ideal classical gas limit. A corollary to Carnot's theorem is proved, asserting that the ratio of the work done over a cycle to the heat absorbed to increase the temperature at constant volume is the same for all bodies at the same volume. As power means, the energy and entropy are incomparable, and a new adiabatic potential is introduced by showing that the volume raised to a characteristic exponent is also the integrating factor for the quantity of heat so that the second law can be based on the property that power means are monotonically increasing functions of their order. The vanishing of the chemical potential in extensive systems implies that energy cannot be transported without matter and is equivalent to the condition that Clapeyron's equation be satisfied.

  12. When ideal and real culture clash - trust, infidelity and condom use

    Directory of Open Access Journals (Sweden)

    L Ackermann

    2003-09-01

    Full Text Available With high rates of HIV transmission in South Africa, the correct and consistent use of condoms has become critically important. The findings reported in this article form part of a larger study that investigated the vulnerability of women to HIV infection. This article concentrates on one dimension of the study: how a clash between real and ideal culture negatively impacts upon condom use. This study, conducted in Bloemfontein, revealed that an ideal culture of trust, resulted in non condom use. On the other hand, this study also revealed that despite the emphasis on an ideal culture of trust, a real culture of infidelity exists. This places individuals at risk of contracting HIV, as condom use is guided by ideal rather than real culture.

  13. When ideal and real culture clash--trust, infidelity and condom use.

    Science.gov (United States)

    Ackermann, L; de Klerk, G W

    2003-08-01

    With high rates of HIV transmission in South Africa, the correct and consistent use of condoms has become critically important. The findings reported in this article form part of a larger study that investigated the vulnerability of women to HIV infection. This article concentrates on one dimension of the study: how a clash between real and ideal culture negatively impacts upon condom use. This study, conducted in Bloemfontein, revealed that an ideal culture of trust, resulted in non condom use. On the other hand, this study also revealed that despite the emphasis on an ideal culture of trust, a real culture of infidelity exists. This places individuals at risk of contracting HIV, as condom use is guided by ideal rather than real culture.

  14. Privacy and confidentiality in pragmatic clinical trials.

    Science.gov (United States)

    McGraw, Deven; Greene, Sarah M; Miner, Caroline S; Staman, Karen L; Welch, Mary Jane; Rubel, Alan

    2015-10-01

    With pragmatic clinical trials, an opportunity exists to answer important questions about the relative risks, burdens, and benefits of therapeutic interventions. However, concerns about protecting the privacy of this information are significant and must be balanced with the imperative to learn from the data gathered in routine clinical practice. Traditional privacy protections for research uses of identifiable information rely disproportionately on informed consent or authorizations, based on a presumption that this is necessary to fulfill ethical principles of respect for persons. But frequently, the ideal of informed consent is not realized in its implementation. Moreover, the principle of respect for persons—which encompasses their interests in health information privacy—can be honored through other mechanisms. Data anonymization also plays a role in protecting privacy but is not suitable for all research, particularly pragmatic clinical trials. In this article, we explore both the ethical foundation and regulatory framework intended to protect privacy in pragmatic clinical trials. We then review examples of novel approaches to respecting persons in research that may have the added benefit of honoring patient privacy considerations. © The Author(s) 2015.

  15. The canonical ensemble redefined - 3. Ideal Bose gas

    International Nuclear Information System (INIS)

    Venkataraman, R.

    1984-12-01

    The ideal Bose gas solved in the redefined ensemble formalism exhibits a discontinuity in the specific heat suggesting that Bose-Einstein condensation is a second order phase transition. The deviations from the classical ideal gas behaviour are larger than those predicted by Gibbs ensemble. Below Tsub(c) the pressure is not independent of the volume. For a certain range of values of VT 3 , the peak in black body radiation shows a shift in the frequency scale and this could be detected, at least in principle, experimentally. (author)

  16. Influence of non-ideality on condensation to aerosol

    Directory of Open Access Journals (Sweden)

    S. Compernolle

    2009-02-01

    Full Text Available Secondary organic aerosol (SOA is a complex mixture of water and organic molecules. Its composition is determined by the presence of semi-volatile or non-volatile compounds, their saturation vapor pressure and activity coefficient. The activity coefficient is a non-ideality effect and is a complex function of SOA composition. In a previous publication, the detailed chemical mechanism (DCM for α-pinene oxidation and subsequent aerosol formation BOREAM was presented. In this work, we investigate with this DCM the impact of non-ideality by simulating smog chamber experiments for α-pinene degradation and aerosol formation and taking the activity coefficient into account of all molecules in the aerosol phase. Several versions of the UNIFAC method are tested for this purpose, and missing parameters for e.g. hydroperoxides and nitrates are inferred from fittings to activity coefficient data generated using the SPARC model. Alternative approaches to deal with these missing parameters are also tested, as well as an activity coefficient calculation method based on Hansen solubility parameters (HSP. It turns out that for most experiments, non-ideality has only a limited impact on the interaction between the organic molecules, and therefore on SOA yields and composition, when water uptake is ignored. The reason is that often, the activity coefficient is on average close to 1 and, specifically for high-VOC experiments, partitioning is not very sensitive on the activity coefficient because the equilibrium is shifted strongly towards condensation. Still, for ozonolysis experiments with low amounts of volatile organic carbon (low-VOC, the UNIFAC parameterization of Raatikainen et al. leads to significantly higher SOA yields (by up to a factor 1.6 compared to the ideal case and to other parameterizations. Water uptake is model dependent, in the order: ideal > UNIFAC-Raatikainen > UNIFAC-Peng > UNIFAC-Hansen ≈ UNIFAC-Magnussen ≈ UNIFAC-Ming. In the absence

  17. Thin-ideal internalization: How much is too much?

    Science.gov (United States)

    Schaefer, Lauren M; Burke, Natasha L; Thompson, J Kevin

    2018-03-16

    Internalization of the thin-ideal is a risk factor for eating disorders that frequently persists into recovery and increases patient risk for relapse. Addressing thin-ideal internalization as a core element of eating disorder prevention and treatment produces significant reductions in eating pathology. However, research has not yet quantified levels of thin-ideal internalization that may signal increased versus decreased risk for disordered eating. To address this gap in the literature, receiver operating characteristic (ROC) curve analysis was used to identify a thin-ideal internalization cutoff score that signified clinically-meaningful eating disorder pathology. 787 college women (age M = 20.17, SD = 2.41; BMI M = 23.58, SD = 5.29) were classified as "healthy" (N = 717) or those with significant disordered eating (N = 70) using established clinical cutoffs for the Eating Disorder Examination-Questionnaire. ROC curve analysis was used to test the performance of the Sociocultural Attitudes Towards Appearance Questionnaire-4 (SATAQ-4) Internalization: Thin/Low Body Fat subscale in predicting disordered eating status, and to identify a cutoff score that maximized sensitivity and specificity to discriminate between healthy and disordered eating samples. Mean SATAQ-4 internalization scores were 3.29 (SD = 0.92) and 4.27 (SD = 0.62) for healthy and disordered eating participants, respectively. The SATAQ-4 internalization scores were good predictors of disordered eating status (area under the curve = 0.81, 95% CI: 0.76-0.86). The optimal cutoff of 3.78 (measured on a 1-5 Likert scale) yielded a sensitivity of 0.81 and specificity of 0.64. Overall, results provide preliminary support for the discriminant validity of SATAQ-4 thin internalization scores and suggest that even moderate levels of thin-ideal internalization may be predictive of clinically-significant eating pathology. It may be important for prevention and intervention work to actively seek to reduce

  18. Twenty weeks of isometric handgrip home training to lower blood pressure in hypertensive older adults: a study protocol for a randomized controlled trial.

    Science.gov (United States)

    Jørgensen, Martin Grønbech; Ryg, Jesper; Danielsen, Mathias Brix; Madeleine, Pascal; Andersen, Stig

    2018-02-09

    Hypertension markedly increases the risk of cardiovascular diseases and overall mortality. Lifestyle modifications, such as increased levels of physical activity, are recommended as the first line of anti-hypertensive treatment. A recent systematic review showed that isometric handgrip (IHG) training was superior to traditional endurance and strength training in lowering resting systolic blood pressure (SBP). The average length of previous IHG training studies is approximately 7.5 weeks with the longest being 10 weeks. Therefore, presently it is unknown if it is possible to further lower blood pressure levels beyond the 10-week mark. Recently, we developed a novel method for monitoring handgrip intensity using a standard Nintendo Wii Board (Wii). The primary aim of this study is to explore the effects of a 20-week IHG home training facilitated by a Wii in hypertensive older adults (50 + years of age) on lowering SBP compared to usual care. Secondary aims are to explore if/when a leveling-off effect on SBP will occur during the 20-week intervention period in the training group and to explore adherence and potential harms related to the IHG home training. Based on previous evidence, we calculated that 50 hypertensive (SBP between 140 and 179 mmHg), older adults (50 + years of age) are needed to achieve a power of 80% or more. Participants will be randomly assigned to either an intervention >group (IHG home training + hypertension guidelines on lifestyle changes) or to a control group (hypertension guidelines on lifestyle changes). Participants in the intervention group will perform IHG home training (30% of maximum grip strength for a total of 8 min per day per hand) three times a week for 20 weeks. Resting blood pressure and maximal handgrip strength will be obtained by a blinded outcome assessor in both groups at specific time points (baseline, follow-up at 5, 10, 15, and 20 weeks) throughout the study. This assessor-blinded, randomized controlled

  19. Intensive lipid lowering with atorvastatin in patients with stable coronary disease

    NARCIS (Netherlands)

    LaRosa, John C.; Grundy, Scott M.; Waters, David D.; Shear, Charles; Barter, Philip; Fruchart, Jean-Charles; Gotto, Antonio M.; Greten, Heiner; Kastelein, John J. P.; Shepherd, James; Wenger, Nanette K.

    2005-01-01

    BACKGROUND: Previous trials have demonstrated that lowering low-density lipoprotein (LDL) cholesterol levels below currently recommended levels is beneficial in patients with acute coronary syndromes. We prospectively assessed the efficacy and safety of lowering LDL cholesterol levels below 100 mg

  20. Perception of various stakeholders regarding clinical drug trial industry in India

    Directory of Open Access Journals (Sweden)

    Rakesh M Parikh

    2011-01-01

    Full Text Available Context: Though India has been thought to be an ideal destination for conduct of clinical drug trials, other smaller countries seem to be doing better. The pace of growth observed during 2005-2009 seems to be plateaued in 2010. Aims: There is an urgent need for introspection and corrective actions. Materials and Methods: An online survey was conducted among various stakeholders from clinical drug trial industry in India regarding their perception about clinical drug trial industry in India. Respondents were requested to rate training of investigator sites, industry, performance of regulatory, etc. Results: Majority of respondent felt that the clinical drug trial industry in India is growing, though India is not utilizing its full potential. Lack of trained investigators and delay in regulatory approvals came out as biggest hurdles. Conclusions: Urgent steps need to be taken in terms of proper training of all stakeholders. Regulatory bodies ought to bring about some radical changes in the system so as to match the other competing nations.

  1. The Place of Idealism in Scientific –Technological Advancement in ...

    African Journals Online (AJOL)

    Idealism, a School of Thought which emphasizes a kind of philosophy that described ultimate reality as 'thought' or 'mind' has fallen under the sledge hammer of some philosophers, especially the empiricists because, the empiricists believe that Idealism has no practical or empirical basis. Due to the current emphasis on ...

  2. Evaluating the clinical and cost effectiveness of a behaviour change intervention for lowering cardiovascular disease risk for people with severe mental illnesses in primary care (PRIMROSE study): study protocol for a cluster randomised controlled trial.

    Science.gov (United States)

    Osborn, David; Burton, Alexandra; Walters, Kate; Nazareth, Irwin; Heinkel, Samira; Atkins, Lou; Blackburn, Ruth; Holt, Richard; Hunter, Racheal; King, Michael; Marston, Louise; Michie, Susan; Morris, Richard; Morris, Steve; Omar, Rumana; Peveler, Robert; Pinfold, Vanessa; Zomer, Ella; Barnes, Thomas; Craig, Tom; Gilbert, Hazel; Grey, Ben; Johnston, Claire; Leibowitz, Judy; Petersen, Irene; Stevenson, Fiona; Hardy, Sheila; Robinson, Vanessa

    2016-02-12

    People with severe mental illnesses die up to 20 years earlier than the general population, with cardiovascular disease being the leading cause of death. National guidelines recommend that the physical care of people with severe mental illnesses should be the responsibility of primary care; however, little is known about effective interventions to lower cardiovascular disease risk in this population and setting. Following extensive peer review, funding was secured from the United Kingdom National Institute for Health Research (NIHR) to deliver the proposed study. The aim of the trial is to test the effectiveness of a behavioural intervention to lower cardiovascular disease risk in people with severe mental illnesses in United Kingdom General Practices. The study is a cluster randomised controlled trial in 70 GP practices for people with severe mental illnesses, aged 30 to 75 years old, with elevated cardiovascular disease risk factors. The trial will compare the effectiveness of a behavioural intervention designed to lower cardiovascular disease risk and delivered by a practice nurse or healthcare assistant, with standard care offered in General Practice. A total of 350 people will be recruited and followed up at 6 and 12 months. The primary outcome is total cholesterol level at the 12-month follow-up and secondary outcomes include blood pressure, body mass index, waist circumference, smoking status, quality of life, adherence to treatments and services and behavioural measures for diet, physical activity and alcohol use. An economic evaluation will be carried out to determine the cost effectiveness of the intervention compared with standard care. The results of this pragmatic trial will provide evidence on the clinical and cost effectiveness of the intervention on lowering total cholesterol and addressing multiple cardiovascular disease risk factors in people with severe mental illnesses in GP Practices. Current Controlled Trials ISRCTN13762819. Date of

  3. Why the Kantian ideal survives medical learning curves, and why it matters.

    Science.gov (United States)

    Brecher, B

    2006-09-01

    The "Kantian ideal" is often misunderstood as invoking individual autonomy rather than rational self legislation. Le Morvan and Stock's otherwise insightful discussion of "Medical learning curves and the Kantian ideal"--for example--draws the mistaken inference that that ideal is inconsistent with the realities of medical practice. But it is not. Rationally to be a patient entails accepting its necessary conditions.

  4. Lower first permanent molars: developing better predictors of spontaneous space closure.

    Science.gov (United States)

    Teo, Terry Kuo-Yih; Ashley, Paul Francis; Derrick, Donald

    2016-02-01

    First, first permanent molars (FPMs) of poor prognosis are often planned for extraction at an 'ideal time' so that second permanent molars (SPMs) erupt favourably to replace them. However for lower FPM extractions, timing is not an accurate predictor of success. The aim of this study was to identify additional radiographic factors that could better predict the degree of spontaneous space closure of the lower SPM following FPM extraction. Data from a previous study of 127 lower SPMs from 66 patients was re-analysed by incorporating additional radiographic factors. These included calcification stage of the bifurcation of the SPM, position of the second premolar, mesial angulation of SPM in relation to the FPM, and presence of the third permanent molar. Results were analysed using ordered logistic regression. Only 58 per cent of FPMs extracted at the 'ideal time' (SPM development at Demirjian stage E) had complete space closure. The best outcomes resulted from a combination of SPMs not at Demirjian development stage G, together with the presence of mesial angulation of the SPM and presence of the third permanent molar, where 85 per cent of those cases had complete space closure. Apart from extraction timing of the FPM, consideration must also be given to the presence of the third permanent molar and angulation of the SPM in order to ensure a reliable degree of spontaneous space closure of the lower SPM. © The Author 2015. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  5. Developmental Idealism: The Cultural Foundations of World Development Programs

    Science.gov (United States)

    Thornton, Arland; Dorius, Shawn F.; Swindle, Jeffrey

    2015-01-01

    This paper extends theory and research concerning cultural models of development beyond family and demographic matters to a broad range of additional factors, including government, education, human rights, daily social conventions, and religion. Developmental idealism is a cultural model—a set of beliefs and values—that identifies the appropriate goals of development and the ends for achieving these goals. It includes beliefs about positive cause and effect relationships among such factors as economic growth, educational achievement, health, and political governance, as well as strong values regarding many attributes, including economic growth, education, small families, gender equality, and democratic governance. This cultural model has spread from its origins among the elites of northwest Europe to elites and ordinary people throughout the world. Developmental idealism has become so entrenched in local, national, and global social institutions that it has now achieved a taken-for-granted status among many national elites, academics, development practitioners, and ordinary people around the world. We argue that developmental idealism culture has been a fundamental force behind many cultural clashes within and between societies, and continues to be an important cause of much global social change. We suggest that developmental idealism should be included as a causal factor in theories of human behavior and social change. PMID:26457325

  6. Low-Dose Creatine Supplementation Lowers Plasma Guanidinoacetate, but Not Plasma Homocysteine, in a Double-Blind, Randomized, Placebo-Controlled Trial123

    Science.gov (United States)

    Peters, Brandilyn A; Hall, Megan N; Liu, Xinhua; Parvez, Faruque; Siddique, Abu B; Shahriar, Hasan; Uddin, Mohammad Nasir; Islam, Tariqul; Ilievski, Vesna; Graziano, Joseph H; Gamble, Mary V

    2015-01-01

    Background: Creatine synthesis from guanidinoacetate consumes ∼50% of s-adenosylmethionine (SAM)–derived methyl groups, accounting for an equivalent proportion of s-adenosylhomocysteine (SAH) and total homocysteine (tHcys) synthesis. Dietary creatine inhibits the synthesis of guanidinoacetate, thereby lowering plasma tHcys in rats. Objective: We tested the hypotheses that creatine supplementation lowers plasma guanidinoacetate, increases blood SAM, lowers blood SAH, and lowers plasma tHcys. Methods: Bangladeshi adults were randomly assigned to receive 1 of 4 treatments for 12 wk: placebo (n = 101), 3 g/d creatine (Cr; n = 101), 400 μg/d folic acid (FA; n = 153), or 3 g/d creatine plus 400 μg/d folic acid (Cr+FA; n = 103). The outcomes of plasma guanidinoacetate and tHcys, as well as whole blood SAM and SAH, were analyzed at baseline and week 12 by HPLC. Treatment effects of creatine supplementation were examined with the use of the group comparisons of Cr vs. placebo and Cr+FA vs. FA. Results: Plasma guanidinoacetate declined by 10.6% (95% CI: 4.9, 15.9) in the Cr group while increasing nonsignificantly in the placebo group (3.7%; 95% CI: −0.8, 8.5) (Pgroup difference = 0.0002). Similarly, plasma guanidinoacetate declined by 9.0% (95% CI: 3.4, 14.2) in the Cr+FA group while increasing in the FA group (7.0%; 95% CI: 2.0, 12.2) (Pgroup difference creatine supplementation downregulates endogenous creatine synthesis, this may not on average lower plasma tHcys in humans. However, tHcys did decrease in those participants who experienced a decline in plasma guanidinoacetate while receiving creatine plus folic acid supplementation. This trial was registered at clinicaltrials.gov as NCT01050556. PMID:26311810

  7. Muscle activation timing and balance response in chronic lower back pain patients with associated radiculopathy.

    Science.gov (United States)

    Frost, Lydia R; Brown, Stephen H M

    2016-02-01

    Patients with chronic low back pain and associated radiculopathy present with neuromuscular symptoms both in their lower back and down their leg; however, investigations of muscle activation have so far been isolated to the lower back. During balance perturbations, it is necessary that lower limb muscles activate with proper timing and sequencing along with the lower back musculature to efficiently regain balance control. Patients with chronic low back pain and radiculopathy and matched controls completed a series of balance perturbations (rapid bilateral arm raise, unanticipated and anticipated sudden loading, and rapid rise to toe). Muscle activation timing and sequencing as well as kinetic response to the perturbations were analyzed. Patients had significantly delayed lower limb muscle activation in rapid arm raise trials as compared to controls. In sudden loading trials, muscle activation timing was not delayed in patients; however, some differences in posterior chain muscle activation sequencing were present. Patients demonstrated less anterior-posterior movement in unanticipated sudden loading trials, and greater medial-lateral movement in rise to toe trials. Patients with low back pain and radiculopathy demonstrated some significant differences from control participants in terms of muscle activation timing, sequencing, and overall balance control. The presence of differences between patients and controls, specifically in the lower limb, indicates that radiculopathy may play a role in altering balance control in these patients. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. The tragedy of Julius Caesar: power, ideal and treason

    Directory of Open Access Journals (Sweden)

    Luís Roberto Barroso

    2018-01-01

    Full Text Available This paper briefly revisits the plot of William Shakespeare’s play The Tragedy of Julius Caesar and seeks to reflect on power and human behavior at the dusk of the Roman Republic. The play, in fact, portrays the tragedy of Brutus, who, moved by idealism and the impetus to protect the Republic, betrayed Caesar and participated in the conspiracy to kill him. The article ends with considerations about love, ideal and treason.

  9. The effect of priming materialism on women's responses to thin-ideal media.

    Science.gov (United States)

    Ashikali, Eleni-Marina; Dittmar, Helga

    2012-12-01

    Consumer culture is characterized by two prominent ideals: the 'body perfect' and the material 'good life'. Although the impact of these ideals has been investigated in separate research literatures, no previous research has examined whether materialism is linked to women's responses to thin-ideal media. Data from several studies confirm that the internalization of materialistic and body-ideal values is positively linked in women. After developing a prime for materialism (N = 50), we present an experimental examination (N = 155) of the effects of priming materialism on women's responses to thin-ideal media, using multiple outcome measures of state body dissatisfaction. Priming materialism affects women's body dissatisfaction after exposure to thin media models, but differently depending on the dimension of body image measured. The two main novel findings are that (1) priming materialism heightens the centrality of appearance to women's self-concept and (2) priming materialism influences the activation of body-related self-discrepancies (BRSDs), particularly for highly materialistic women. Exposure to materialistic media has a clear influence on women's body image, with trait materialism a further vulnerability factor for negative exposure effects in response to idealized, thin media models. ©2011 The British Psychological Society.

  10. A New Perspective on Classical Ideal Gases

    Directory of Open Access Journals (Sweden)

    Fabrice Philippe

    2013-08-01

    Full Text Available The ideal-gas barometric and pressure laws are derived from the Democritian concept of independent corpuscles moving in vacuum, plus a principle of simplicity, namely that these laws are independent of the kinetic part of the Hamiltonian. A single corpuscle in contact with a heat bath in a cylinder and submitted to a constant force (weight is considered. The paper importantly supplements a previously published paper: First, the stability of ideal gases is established. Second, we show that when walls separate the cylinder into parts and are later removed, the entropy is unaffected. We obtain full agreement with Landsberg’s and others’ (1994 classical thermodynamic result for the entropy of a column of gas submitted to gravity.

  11. Design and rationale of the QUAZAR Lower-Risk MDS (AZA-MDS-003) trial: a randomized phase 3 study of CC-486 (oral azacitidine) plus best supportive care vs placebo plus best supportive care in patients with IPSS lower-risk myelodysplastic syndromes and poor prognosis due to red blood cell transfusion-dependent anemia and thrombocytopenia.

    Science.gov (United States)

    Garcia-Manero, Guillermo; Almeida, Antonio; Giagounidis, Aristoteles; Platzbecker, Uwe; Garcia, Regina; Voso, Maria Teresa; Larsen, Stephen R; Valcarcel, David; Silverman, Lewis R; Skikne, Barry; Santini, Valeria

    2016-01-01

    CC-486 is an oral formulation of the epigenetic modifier azacitidine. In an expanded phase 1 trial, CC-486 demonstrated clinical and biological activity in patients with International Prognostic Scoring System (IPSS) lower-risk (low- and intermediate-1-risk) myelodysplastic syndromes (MDS) with poor prognostic features including anemia and/or thrombocytopenia who may have required red blood cell or platelet transfusions. The overall response rate was 40 %, including hematologic improvement in 28 % of patients and RBC transfusion independence sustained for 56 days in 47 % of patients with baseline transfusion dependence. Based on the results of this study, the randomized, placebo-controlled phase 3 QUAZAR Lower-Risk MDS trial (AZA-MDS-003) was initiated. The design and rationale for this trial comparing CC-486 with placebo for the treatment of patients with IPSS lower-risk MDS with poor prognostic features are described. Patients must have IPSS lower-risk MDS with red blood cell (RBC) transfusion-dependent anemia and thrombocytopenia. Eligible patients are randomized 1:1 to receive 300 mg of CC-486 or placebo once daily for the first 21 days of 28-day treatment cycles. Disease status assessments occur at the end of cycle 6 and patients may continue to receive treatment unless there is evidence of progressive disease, lack of efficacy, or unacceptable toxicity. The primary endpoint is RBC transfusion independence for ≥ 84 days, assessed according to International Working Group 2006 criteria. Secondary endpoints include overall survival, hematologic response including platelet response and erythroid response, RBC transfusion independence for ≥ 56 days, duration of RBC transfusion independence, time to RBC transfusion independence, rate of acute myeloid leukemia (AML) progression, time to AML progression, clinically significant bleeding events, safety, health-related quality of life, and healthcare resource utilization. This study will provide data

  12. Self-guide framing and persuasion: responsibly increasing message processing to ideal levels.

    Science.gov (United States)

    Evans, Lisa M; Petty, Richard E

    2003-03-01

    The current research examines the effect that framing persuasive messages in terms of self-guides (ideal vs. ought) has on the attitudes and cognitive responses of individuals with chronic ideal versus ought self-guides. The strength of participants' ideal and ought self-guides and the magnitude of participants' ideal and ought self-discrepancies were measured using a computerized reaction time program. One week later, participants read a persuasive message about a fictional breakfast product, framed in terms of either ideals or oughts. Matching framing to stronger self-guide led to enhanced message processing activity, especially among individuals who were low in need for cognition. Individuals who read messages framed to match their stronger self-guides paid more attention to argument quality, as reflected in their attitudes and cognitive responses. Messages with self-guide framing that matched individuals' stronger self-discrepancies did not have this effect on processing.

  13. A Darker Shade of Love: Machiavellianism and Positive Assortative Mating Based on Romantic Ideals

    Science.gov (United States)

    Ináncsi, Tamás; Láng, András; Bereczkei, Tamás

    2016-01-01

    Machiavellianism is a personality trait that is characterized by manipulative and exploitative attitude toward others, lack of empathy, and a cynical view of human nature. In itself or as part of the Dark Triad it has been the target of several studies investigating romantic relations. Nevertheless, the relationship between Machiavellianism and romantic ideals has not been revealed yet. An undergraduate sample of 143 (92 females) with an average age of 19.83 years (SD = 1.51 years) filled out self-report measures of Machiavellianism (Mach-IV Scale) and romantic ideals (Ideal Standards Scale and NEO-FFI-IDEAL). According to our results, Machiavellianism correlated negatively with the importance of partner’s warmth-trustworthiness, extraversion, openness, agreeableness, and with the importance of intimacy and loyalty in their ideal relationships. Machiavellianism correlated positively with the ideal partner’s possession over status and resources. Explorative factor analysis revealed three components of ideal partner’s characteristics. Machiavellianism loaded significantly on two out of three components. Results are discussed with regard to Ideal Standards Model and the Big Five model of personality. PMID:27247697

  14. Ambivalent Sexism in Close Relationships: (Hostile) Power and (Benevolent) Romance Shape Relationship Ideals

    Science.gov (United States)

    Lee, Tiane L.; Fiske, Susan T.; Glick, Peter; Chen, Zhixia

    2013-01-01

    Gender-based structural power and heterosexual dependency produce ambivalent gender ideologies, with hostility and benevolence separately shaping close-relationship ideals. The relative importance of romanticized benevolent versus more overtly power-based hostile sexism, however, may be culturally dependent. Testing this, northeast US (N=311) and central Chinese (N=290) undergraduates rated prescriptions and proscriptions (ideals) for partners and completed Ambivalent Sexism and Ambivalence toward Men Inventories (ideologies). Multiple regressions analyses conducted on group-specific relationship ideals revealed that benevolent ideologies predicted partner ideals, in both countries, especially for US culture’s romance-oriented relationships. Hostile attitudes predicted men’s ideals, both American and Chinese, suggesting both societies’ dominant-partner advantage. PMID:23914004

  15. Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial.

    Science.gov (United States)

    Bluth, T; Teichmann, R; Kiss, T; Bobek, I; Canet, J; Cinnella, G; De Baerdemaeker, L; Gregoretti, C; Hedenstierna, G; Hemmes, S N; Hiesmayr, M; Hollmann, M W; Jaber, S; Laffey, J G; Licker, M J; Markstaller, K; Matot, I; Müller, G; Mills, G H; Mulier, J P; Putensen, C; Rossaint, R; Schmitt, J; Senturk, M; Serpa Neto, A; Severgnini, P; Sprung, J; Vidal Melo, M F; Wrigge, H; Schultz, M J; Pelosi, P; Gama de Abreu, M

    2017-04-28

    Postoperative pulmonary complications (PPCs) increase the morbidity and mortality of surgery in obese patients. High levels of positive end-expiratory pressure (PEEP) with lung recruitment maneuvers may improve intraoperative respiratory function, but they can also compromise hemodynamics, and the effects on PPCs are uncertain. We hypothesized that intraoperative mechanical ventilation using high PEEP with periodic recruitment maneuvers, as compared with low PEEP without recruitment maneuvers, prevents PPCs in obese patients. The PRotective Ventilation with Higher versus Lower PEEP during General Anesthesia for Surgery in OBESE Patients (PROBESE) study is a multicenter, two-arm, international randomized controlled trial. In total, 2013 obese patients with body mass index ≥35 kg/m 2 scheduled for at least 2 h of surgery under general anesthesia and at intermediate to high risk for PPCs will be included. Patients are ventilated intraoperatively with a low tidal volume of 7 ml/kg (predicted body weight) and randomly assigned to PEEP of 12 cmH 2 O with lung recruitment maneuvers (high PEEP) or PEEP of 4 cmH 2 O without recruitment maneuvers (low PEEP). The occurrence of PPCs will be recorded as collapsed composite of single adverse pulmonary events and represents the primary endpoint. To our knowledge, the PROBESE trial is the first multicenter, international randomized controlled trial to compare the effects of two different levels of intraoperative PEEP during protective low tidal volume ventilation on PPCs in obese patients. The results of the PROBESE trial will support anesthesiologists in their decision to choose a certain PEEP level during general anesthesia for surgery in obese patients in an attempt to prevent PPCs. ClinicalTrials.gov identifier: NCT02148692. Registered on 23 May 2014; last updated 7 June 2016.

  16. The voice of the customer: consumers define the ideal battery charger.

    Science.gov (United States)

    Lane, J P; Usiak, D J; Stone, V I; Scherer, M J

    1997-01-01

    The Rehabilitation Engineering Research Center on Technology Evaluation and Transfer is exploring how the users of assistive technology devices define the ideal device. This work is called the Consumer Ideal Product program. The results show what device characteristics are most and least important, indicating where to place the priority on product features and functions from the consumer's perspective. The "voice of the customer" can be used (1) to define the ideal characteristics of a product, (2) to make trade-offs in product design and function improvements based on their relative importance to the consumer, (3) to compare the characteristics of existing products against the characteristics of the ideal product, or (4) to generate a product checklist for consumers to use when making a purchase decision. This paper presents the results of consumers' defining the ideal battery charger. Four focus groups generated the survey's content, then 100 experienced users rated 159 characteristics organized under 11 general evaluation criteria. The consumers placed the highest importance on characteristics from the general evaluation criteria of product reliability, effectiveness, and physical security/safety. The findings should help manufacturers and vendors improve their products and services and help professionals and consumers make informed choices.

  17. Complexity of culture: the role of identity and context in bicultural individuals' body ideals.

    Science.gov (United States)

    Guan, Mei; Lee, Fiona; Cole, Elizabeth R

    2012-07-01

    Culture plays an important role in shaping body image, and people from different cultures have different beliefs about what constitutes the "ideal" body type. This study examines the relationship between culture and body ideals in Asian-American and Black-American women. Results from two studies show that subjective cultural identity and situational cultural cues had different relationships with body ideals. Among Asian-American women, identification with Asian culture was related to a thinner body ideal, but exposure to Asian cultural cues (relative to American cultural cues) was related to a thicker body ideal. Among Black-American women, identification with Black culture was related to a thicker body ideal, but exposure to Black cultural cues (relative to American cultural cues) was related to a thinner body ideal. These results have theoretical and practical implications for understanding how internal and external manifestations of culture can differentially influence body image.

  18. Current and ideal skin tone: Associations with tanning behavior among sexual minority men.

    Science.gov (United States)

    Klimek, Patrycja; Lamb, Kalina M; Nogg, Kelsey A; Rooney, Benjamin M; Blashill, Aaron J

    2018-06-01

    Sexual minority men have high rates of skin cancer, yet little is known about skin cancer risk behaviors in this population. It was hypothesized that current skin tone would moderate the association between darker ideals and tanning behaviors. Data were collected online from 231 sexual minority men in San Diego, United States of America, with a mean age of 24.66 (SD = 5.44). Ideal and current skin tone ratings and indoor and outdoor tanning behaviors were assessed. Darker ideals were significantly associated with increased indoor and outdoor tanning. The effect of darker ideals on tanning was strongest among individuals with lighter current skin tone, indicating a significant interaction. Sexual minority men whose perceived skin tone did not match their ideal were more likely to engage in skin cancer risk behaviors. Future skin cancer prevention programs aimed at sexual minority men may consider techniques that modify ideal skin tone internalization. Copyright © 2018 Elsevier Ltd. All rights reserved.

  19. Structural arrest in an ideal gas

    NARCIS (Netherlands)

    Ketel, W. van; Das, C.; Frenkel, D.

    2005-01-01

    We report a molecular dynamics study of a simple model system that has the static properties of an ideal gas, yet exhibits nontrivial "glassy" dynamics behavior at high densities. The constituent molecules of this system are constructs of three infinitely thin hard rods of length L, rigidly joined

  20. Ideal gas scattering kernel for energy dependent cross-sections

    International Nuclear Information System (INIS)

    Rothenstein, W.; Dagan, R.

    1998-01-01

    A third, and final, paper on the calculation of the joint kernel for neutron scattering by an ideal gas in thermal agitation is presented, when the scattering cross-section is energy dependent. The kernel is a function of the neutron energy after scattering, and of the cosine of the scattering angle, as in the case of the ideal gas kernel for a constant bound atom scattering cross-section. The final expression is suitable for numerical calculations

  1. Perceptions of Ideal and Former Partners’ Personality and Similarity

    Directory of Open Access Journals (Sweden)

    Pieternel Dijkstra

    2010-12-01

    Full Text Available The present study aimed to test predictions based on both the ‗similarity-attraction‘ hypothesis and the ‗attraction-similarity‘ hypothesis, by studying perceptions of ideal and former partners. Based on the ‗similarity-attraction‘ hypothesis, we expected individuals to desire ideal partners who are similar to the self in personality. In addition, based on the ‗attraction-similarity hypothesis‘, we expected individuals to perceive former partners as dissimilar to them in terms of personality. Findings showed that, whereas the ideal partner was seen as similar to and more positive than the self, the former partner was seen as dissimilar to and more negative than the self. In addition, our study showed that individuals did not rate similarity in personality as very important when seeking a mate. Our findings may help understand why so many relationships end in divorce due to mismatches in personality.

  2. The Actual and Ideal Sexual Self Concept in the Context of Genital Pain Using Implicit and Explicit Measures.

    Science.gov (United States)

    Dewitte, Marieke; De Schryver, Maarten; Heider, Niclas; De Houwer, Jan

    2017-05-01

    The experience of pain during sexual intercourse generates significant distress and sexual impairments, which is likely to affect sexual identity and become a threat to the sense of self. To explore the role of the concept of the sexual self in the context of genital pain by measuring different states of self (ie, actual vs ideal) at different levels of responding (ie, explicit vs implicit) and examine their associations with sexual, emotional, and pain-related variables. Thirty young women who identified with genital pain and 29 women without pain completed (i) two versions of the Relational Responding Task as a measurement of implicit actual and ideal sexual self; (ii) explicit ratings of the actual and the ideal sexual self; and (iii) measurements of sexual self-esteem, global self-esteem, depression, sexual satisfaction, sexual distress or depression, sexual frequency, and pain experiences. Women with genital pain scored lower on the explicit and implicit actual-self measurements than women without pain but did not differ in their ideal self. Furthermore, the pain group reported higher ideal- than actual-self scores at the explicit level. Actual- and ideal-self measurements had differential effects on sexual, emotional, and behavioral outcome variables. In general, rating the ideal self higher than the actual self was related to more negative outcomes. Pain-related variables were predicted only by the implicit measurements, showing that the high pain group reported more pain, fear of pain, and a stronger tendency to continue with sex despite the pain when perceiving themselves as sexually less competent and when this perception did not match their ideal self. Therapeutic interventions might benefit from discussing women's internal guides for self, decreasing potential discrepancies, and developing identity-related motivational treatments that target the emotional discomfort and maladaptive behavioral strategies that result from trying to conform with their

  3. Clinical trials in allied medical fields: A cross-sectional analysis of World Health Organization International Clinical Trial Registry Platform

    Directory of Open Access Journals (Sweden)

    S. Kannan

    2016-03-01

    Conclusion: The number of clinical trials done in allied fields of medicine other than the allopathic system has lowered down, and furthermore focus is required regarding the methodological quality of these trials and more support from various organizations.

  4. Complex Neutrosophic Subsemigroups and Ideals

    Directory of Open Access Journals (Sweden)

    Muhammad Gulistan

    2018-01-01

    Full Text Available In this article we study the idea of complex neutrosophic subsemigroups. We define the Cartesian product of complex neutrosophic subsemigroups, give some examples and study some of its related results. We also define complex neutrosophic (left, right, interior ideal in semigroup. Furthermore, we introduce the concept of characteristic function of complex neutrosophic sets, direct product of complex neutrosophic sets and study some results prove on its.

  5. Calibration of non-ideal thermal conductivity sensors

    Directory of Open Access Journals (Sweden)

    N. I. Kömle

    2013-04-01

    Full Text Available A popular method for measuring the thermal conductivity of solid materials is the transient hot needle method. It allows the thermal conductivity of a solid or granular material to be evaluated simply by combining a temperature measurement with a well-defined electrical current flowing through a resistance wire enclosed in a long and thin needle. Standard laboratory sensors that are typically used in laboratory work consist of very thin steel needles with a large length-to-diameter ratio. This type of needle is convenient since it is mathematically easy to derive the thermal conductivity of a soft granular material from a simple temperature measurement. However, such a geometry often results in a mechanically weak sensor, which can bend or fail when inserted into a material that is harder than expected. For deploying such a sensor on a planetary surface, with often unknown soil properties, it is necessary to construct more rugged sensors. These requirements can lead to a design which differs substantially from the ideal geometry, and additional care must be taken in the calibration and data analysis. In this paper we present the performance of a prototype thermal conductivity sensor designed for planetary missions. The thermal conductivity of a suite of solid and granular materials was measured both by a standard needle sensor and by several customized sensors with non-ideal geometry. We thus obtained a calibration curve for the non-ideal sensors. The theory describing the temperature response of a sensor with such unfavorable length-to-diameter ratio is complicated and highly nonlinear. However, our measurements reveal that over a wide range of thermal conductivities there is an almost linear relationship between the result obtained by the standard sensor and the result derived from the customized, non-ideal sensors. This allows for the measurement of thermal conductivity values for harder soils, which are not easily accessible when using

  6. Ideal MHD Stability Prediction and Required Power for EAST Advanced Scenario

    International Nuclear Information System (INIS)

    Chen Junjie; Li Guoqiang; Qian Jinping; Liu Zixi

    2012-01-01

    The Experimental Advanced Superconducting Tokamak (EAST) is the first fully superconducting tokamak with a D-shaped cross-sectional plasma presently in operation. The ideal magnetohydrodynamic (MHD) stability and required power for the EAST advanced tokamak (AT) scenario with negative central shear and double transport barrier (DTB) are investigated. With the equilibrium code TOQ and stability code GATO, the ideal MHD stability is analyzed. It is shown that a moderate ratio of edge transport barriers' (ETB) height to internal transport barriers' (ITBs) height is beneficial to ideal MHD stability. The normalized beta β N limit is about 2.20 (without wall) and 3.70 (with ideal wall). With the scaling law of energy confinement time, the required heating power for EAST AT scenario is calculated. The total heating power P t increases as the toroidal magnetic field B T or the normalized beta β N is increased. (magnetically confined plasma)

  7. Ideal MHD Stability Prediction and Required Power for EAST Advanced Scenario

    Science.gov (United States)

    Chen, Junjie; Li, Guoqiang; Qian, Jinping; Liu, Zixi

    2012-11-01

    The Experimental Advanced Superconducting Tokamak (EAST) is the first fully superconducting tokamak with a D-shaped cross-sectional plasma presently in operation. The ideal magnetohydrodynamic (MHD) stability and required power for the EAST advanced tokamak (AT) scenario with negative central shear and double transport barrier (DTB) are investigated. With the equilibrium code TOQ and stability code GATO, the ideal MHD stability is analyzed. It is shown that a moderate ratio of edge transport barriers' (ETB) height to internal transport barriers' (ITBs) height is beneficial to ideal MHD stability. The normalized beta βN limit is about 2.20 (without wall) and 3.70 (with ideal wall). With the scaling law of energy confinement time, the required heating power for EAST AT scenario is calculated. The total heating power Pt increases as the toroidal magnetic field BT or the normalized beta βN is increased.

  8. Good feelings in christianity and buddhism: religious differences in ideal affect.

    Science.gov (United States)

    Tsai, Jeanne L; Miao, Felicity F; Seppala, Emma

    2007-03-01

    Affect valuation theory (AVT) predicts cultural variation in the affective states that people ideally want to feel (i.e., "ideal affect"). National and ethnic comparisons support this prediction: For instance, European Americans (EA) value high arousal positive (HAP) states (e.g., excitement) more and low arousal positive (LAP) states (e.g., calm) less than Hong Kong Chinese. In this article, the authors examine whether religions differ in the ideal affective states they endorse. The authors predicted that Christianity values HAP more and LAP less than Buddhism. In Study 1, they compared Christian and Buddhist practitioners' ideal affect. In Studies 2 and 3, they compared the endorsement of HAP and LAP in Christian and Buddhist classical texts (e.g., Gospels, Lotus Sutra) and contemporary self-help books (e.g., Your Best Life Now, Art of Happiness). Findings supported predictions, suggesting that AVT applies to religious and to national and ethnic cultures.

  9. Regular shock refraction in planar ideal MHD

    International Nuclear Information System (INIS)

    Delmont, P; Keppens, R

    2010-01-01

    We study the classical problem of planar shock refraction at an oblique density discontinuity, separating two gases at rest, in planar ideal (magneto)hydrodynamics. In the hydrodynamical case, 3 signals arise and the interface becomes Richtmyer-Meshkov unstable due to vorticity deposition on the shocked contact. In the magnetohydrodynamical case, on the other hand, when the normal component of the magnetic field does not vanish, 5 signals will arise. The interface then typically remains stable, since the Rankine-Hugoniot jump conditions in ideal MHD do not allow for vorticity deposition on a contact discontinuity. We present an exact Riemann solver based solution strategy to describe the initial self similar refraction phase. Using grid-adaptive MHD simulations, we show that after reflection from the top wall, the interface remains stable.

  10. Increased body satisfaction after exposure to thin ideal children's television in young girls showing thin ideal internalisation

    NARCIS (Netherlands)

    Anschutz, Doeschka J; Engels, Rutger C M E; van Strien, Tatjana

    2012-01-01

    This study tested the direct effect of watching thin ideal children's television on body satisfaction in preadolescent girls (6-8 years old). A within-subject design was used in which girls (N = 51) were tested three times. They watched television clips in random order containing either (1) thin

  11. Rationale and Design of Randomized Evaluation of Aggressive or Moderate Lipid Lowering Therapy with Pitavastatin in Coronary Artery Disease (REAL-CAD) Trial.

    Science.gov (United States)

    Miyauchi, Katsumi; Kimura, Takeshi; Shimokawa, Hiroaki; Daida, Hiroyuki; Iimuro, Satoshi; Iwata, Hiroshi; Ozaki, Yukio; Sakuma, Ichiro; Nakagawa, Yoshihisa; Hibi, Kiyoshi; Hiro, Takafumi; Fukumoto, Yoshihiro; Hokimoto, Seiji; Ohashi, Yasuo; Ohtsu, Hiroshi; Saito, Yasushi; Matsuzaki, Masunori; Nagai, Ryozo

    2018-03-30

    Large-scale clinical trials in patients in Western countries with coronary artery disease (CAD) have found that aggressive lipid-lowering therapy using high-dose statins reduces cardiovascular (CV) events further than low-dose statins. However, such evidence has not yet been fully established in Asian populations, including in Japan. The Randomized Evaluation of Aggressive or Moderate Lipid-Lowering Therapy with Pitavastatin in Coronary Artery Disease (REAL-CAD) study addresses whether intensification of statin therapy improves clinical outcomes in Japanese patients with CAD.REAL-CAD is a prospective, multicenter, randomized, open-label, blinded-endpoint, physician-initiated phase 4 trial in Japan. The study will recruit up to 12,600 patients with stable CAD. Patients are assigned to receive either pitavastatin 1 mg/day or pitavastatin 4 mg/day. LDL-C levels are expected to reach approximate mean values of 100 mg/dL in the low-dose pitavastatin group and 80 mg/dL in the high-dose group. The primary endpoint is the time to occurrence of a major CV event, including CV death, non-fatal myocardial infarction, non-fatal ischemic stroke, and unstable angina requiring emergency hospitalization during an average of 5 years. The large number of patients and the long follow-up period in the REAL-CAD study should ensure that there is adequate power to definitively determine if reducing LDL-C levels to approximately 80 mg/dL by high-dose statin can provide additional clinical benefit.After the study is completed, we will have categorical evidence on the optimal statin dose and target LDL-C level for secondary prevention in Japanese patients.

  12. Implementing an exercise-training programme to prevent lower-limb injuries: considerations for the development of a randomised controlled trial intervention delivery plan.

    Science.gov (United States)

    Finch, Caroline F; White, Peta; Twomey, Dara; Ullah, Shahid

    2011-08-01

    To identify important considerations for the delivery of an exercise training intervention in a randomised controlled trial to maximise subsequent participation in that randomised controlled trial and intervention uptake. A cross-sectional survey, with a theoretical basis derived from the Health Belief Model (HBM) and the Reach, Efficacy/Effectiveness, Adoption, Implementation and Maintenance (RE-AIM) framework. 374 male senior Australian Football players, aged 17-38 years. Beliefs about lower-limb injury causation/prevention, and the relative value of exercise training for performance and injury prevention. The data are interpreted within HBM constructs and implications for subsequent intervention implementation considered within the RE-AIM framework. Ordinal logistic regression compared belief scores across player characteristics. 74.4% of players agreed that doing specific exercises during training would reduce their risk of lower-limb injury and would be willing to undertake them. However, 64.1% agreed that training should focus more on improving game performance than injury prevention. Younger players (both in terms of age and playing experience) generally had more positive views. Players were most supportive of kicking (98.9%) and ball-handling (97.0%) skills for performance and warm-up runs and cool-downs (both 91.5%) for injury prevention. Fewer than three-quarters of all players believed that balance (69.2%), landing (71.3%) or cutting/stepping (72.8) training had injury-prevention benefits. Delivery of future exercise training programmes for injury prevention aimed at these players should be implemented as part of routine football activities and integrated with those as standard practice, as a means of associating them with training benefits for this sport.

  13. Estimation of the Ideal Lumbar Lordosis to Be Restored From Spinal Fusion Surgery: A Predictive Formula for Chinese Population.

    Science.gov (United States)

    Xu, Leilei; Qin, Xiaodong; Zhang, Wen; Qiao, Jun; Liu, Zhen; Zhu, Zezhang; Qiu, Yong; Qian, Bang-ping

    2015-07-01

    A prospective, cross-sectional study. To determine the independent variables associated with lumbar lordosis (LL) and to establish the predictive formula of ideal LL in Chinese population. Several formulas have been established in Caucasians to estimate the ideal LL to be restored for lumbar fusion surgery. However, there is still a lack of knowledge concerning the establishment of such predictive formula in Chinese population. A total of 296 asymptomatic Chinese adults were prospectively recruited. The relationships between LL and variables including pelvic incidence (PI), age, sex, and body mass index were investigated to determine the independent factors that could be used to establish the predictive formula. For the validation of the current formula, other 4 reported predictive formulas were included. The absolute value of the gap between the actual LL and the ideal LL yielded by these formulas was calculated and then compared between the 4 reported formulas and the current one to determine its reliability in predicting the ideal LL. The logistic regression analysis showed that there were significant associations of LL with PI and age (R = 0.508, P < 0.001 for PI; R = 0.088, P = 0.03 for age). The formula was, therefore, established as follows: LL = 0.508 × PI - 0.088 × Age + 28.6. When applying our formula to these subjects, the gap between the predicted ideal LL and the actual LL was averaged 3.9 ± 2.1°, which was significantly lower than that of the other 4 formulas. The calculation formula derived in this study can provide a more accurate prediction of the LL for the Chinese population, which could be used as a tool for decision making to restore the LL in lumbar corrective surgery. 3.

  14. Effect of Grain Size on Differential Desorption of Volatile Species and on Non-ideal MHD Diffusivity

    Science.gov (United States)

    Zhao, Bo; Caselli, Paola; Li, Zhi-Yun

    2018-05-01

    We developed a chemical network for modeling the chemistry and non-ideal MHD effects from the collapsing dense molecular clouds to protostellar disks. First, we re-formulated the cosmic-ray desorption rate by considering the variations of desorption rate over the grain size distribution. We find that the differential desorption of volatile species is amplified by the grains larger than 0.1 μm, because larger grains are heated to a lower temperature by cosmic-rays and hence more sensitive to the variations in binding energies. As a result, atomic nitrogen N is ˜2 orders of magnitude more abundant than CO; N2H+ also becomes a few times more abundant than HCO+ due to the increased gas-phase N2. However, the changes in ionization fraction due to freeze-out and desorption only have minor effects on the non-ideal MHD diffusivities. Our chemical network confirms that the very small grains (VSGs: below a few 100 Å) weakens the efficiency of both ambipolar diffusion and Hall effect. In collapsing dense cores, a maximum ambipolar diffusion is achieved when truncating the MRN size distribution at 0.1 μm, and for a maximum Hall effect, the truncation occurs at 0.04 μm. We conclude that the grain size distribution is crucial to the differential depletion between CO and N2 related molecules, as well as to the non-ideal MHD diffusivities in dense cores.

  15. Conference on Arithmetic and Ideal Theory of Rings and Semigroups

    CERN Document Server

    Fontana, Marco; Geroldinger, Alfred; Olberding, Bruce

    2016-01-01

    This book consists of both expository and research articles solicited from speakers at the conference entitled "Arithmetic and Ideal Theory of Rings and Semigroups," held September 22–26, 2014 at the University of Graz, Graz, Austria. It reflects recent trends in multiplicative ideal theory and factorization theory, and brings together for the first time in one volume both commutative and non-commutative perspectives on these areas, which have their roots in number theory, commutative algebra, and algebraic geometry. Topics discussed include topological aspects in ring theory, Prüfer domains of integer-valued polynomials and their monadic submonoids, and semigroup algebras. It will be of interest to practitioners of mathematics and computer science, and researchers in multiplicative ideal theory, factorization theory, number theory, and algebraic geometry.

  16. Ideal Gas Laws: Experiments for General Chemistry

    Science.gov (United States)

    Deal, Walter J.

    1975-01-01

    Describes a series of experiments designed to verify the various relationships implicit in the ideal gas equation and shows that the success of the Graham's law effusion experiments can be explained by elementary hydrodynamics. (GS)

  17. Complementary construction of ideal nonimaging concentrators and its applications.

    Science.gov (United States)

    Gordon, J M

    1996-10-01

    A construction principle for ideal nonimaging concentrators based on the complementary edge rays outside the nominal field of view is presented, with illustrations for the trumpet, compound parabolic concentrator, and compound hyperbolic concentrator. A simple string construction for the trumpet concentrator is shown to follow from this observation-the trumpet having been the one ideal concentrator for which no string-construction method had previously been noted. An application of these observations for solar concentrator design when nonisothermal receivers are advantageous is also presented.

  18. Impact of Site Selection and Study Conduct on Outcomes in Global Clinical Trials.

    Science.gov (United States)

    Sarwar, Chaudhry M S; Vaduganathan, Muthiah; Butler, Javed

    2017-08-01

    There are over 25 million patients living with heart failure globally. Overall, and especially post-discharge, clinical outcomes have remained poor in heart failure despite multiple trials, with both successes and failures over the last two decades. Matching therapies to the right patient population, identifying high-quality sites, and ensuring optimal trial design and execution represent important considerations in the development of novel therapeutics in this space. While clinical trials have undergone rapid globalization, this has come with regional variation in comorbidities, clinical parameters, and even clinical outcomes and treatment effects across international sites. These issues have now highlighted knowledge gaps about the conduct of trials, selection of study sites, and an unmet need to develop and identify "ideal" sites. There is a need for all stakeholders, including academia, investigators, healthcare organizations, patient advocacy groups, industry sponsors, research organizations, and regulatory authorities, to work as a multidisciplinary group to address these problems and develop practical solutions to improve trial conduct, efficiency, and execution. We review these trial-level issues using examples from contemporary studies to inform and optimize the design of future global clinical trials in heart failure.

  19. Clinical Trials

    Medline Plus

    Full Text Available ... benefits of lowering high blood pressure in the elderly outweighed the risks. Other examples of clinical trials ... child to enroll. Also, children aged 7 and older often must agree (assent) to take part ... about how you feel. Some people will need to travel or stay in hospitals ...

  20. On finitely generated modules whose first nonzero Fitting ideals are regular

    Directory of Open Access Journals (Sweden)

    Somayeh Hadjirezaei

    2018-01-01

    Full Text Available A finitely generated $R$-module is said to be a module of type ($F_r$ if its $(r-1$-th Fitting ideal is the zero ideal and its $r$-th Fitting ideal is a regular ideal. Let $R$ be a commutative ring and $N$ be a submodule of  $R^n$ which is generated by columns of  a matrix $A=(a_{ij}$ with $a_{ij}in R$ for all $1leq ileq n$, $jin Lambda$, where $Lambda $ is a (possibly infinite index set.  Let  $M=R^n/N$ be  a module of type ($F_{n-1}$ and ${rm T}(M$ be the submodule of $M$ consisting of all elements of $M$ that are annihilated by a regular element of $R$. For $ lambdain Lambda $, put $M_lambda=R^n/$. The main result of this paper asserts that if $M_lambda $ is a regular $R$-module, for some $lambdainLambda$, then $M/{rm T}(Mcong M_lambda/{rm T}(M_lambda$. Also it is shown that if $M_lambda$ is a regular torsionfree $R$-module, for some $lambdain Lambda$, then $ Mcong M_lambda. $ As a consequence we characterize all  non-torsionfree modules over a regular ring, whose first nonzero Fitting ideals are maximal.

  1. Thromboprophylaxis after Knee Arthroscopy and Lower-Leg Casting.

    Science.gov (United States)

    van Adrichem, Raymond A; Nemeth, Banne; Algra, Ale; le Cessie, Saskia; Rosendaal, Frits R; Schipper, Inger B; Nelissen, Rob G H H; Cannegieter, Suzanne C

    2017-02-09

    The use of thromboprophylaxis to prevent clinically apparent venous thromboembolism after knee arthroscopy or casting of the lower leg is disputed. We compared the incidence of symptomatic venous thromboembolism after these procedures between patients who received anticoagulant therapy and those who received no anticoagulant therapy. We conducted two parallel, pragmatic, multicenter, randomized, controlled, open-label trials with blinded outcome evaluation: the POT-KAST trial, which included patients undergoing knee arthroscopy, and the POT-CAST trial, which included patients treated with casting of the lower leg. Patients were assigned to receive either a prophylactic dose of low-molecular-weight heparin (for the 8 days after arthroscopy in the POT-KAST trial or during the full period of immobilization due to casting in the POT-CAST trial) or no anticoagulant therapy. The primary outcomes were the cumulative incidences of symptomatic venous thromboembolism and major bleeding within 3 months after the procedure. In the POT-KAST trial, 1543 patients underwent randomization, of whom 1451 were included in the intention-to-treat population. Venous thromboembolism occurred in 5 of the 731 patients (0.7%) in the treatment group and in 3 of the 720 patients (0.4%) in the control group (relative risk, 1.6; 95% confidence interval [CI], 0.4 to 6.8; absolute difference in risk, 0.3 percentage points; 95% CI, -0.6 to 1.2). Major bleeding occurred in 1 patient (0.1%) in the treatment group and in 1 (0.1%) in the control group (absolute difference in risk, 0 percentage points; 95% CI, -0.6 to 0.7). In the POT-CAST trial, 1519 patients underwent randomization, of whom 1435 were included in the intention-to-treat population. Venous thromboembolism occurred in 10 of the 719 patients (1.4%) in the treatment group and in 13 of the 716 patients (1.8%) in the control group (relative risk, 0.8; 95% CI, 0.3 to 1.7; absolute difference in risk, -0.4 percentage points; 95% CI, -1.8 to 1

  2. Time-dependent behavior of D-dimensional ideal quantum gases

    International Nuclear Information System (INIS)

    Oh, Suhk Kun

    1985-01-01

    The time-dependent behavior of D-dimensional ideal quantum gases is studied within the Mori formalism and its extension by Lee. In the classical limit, the time-dependent behavior is found to be independent of the dimensionality D of the system and is characterized by an extremely damped Gaussian relaxation function. However, at T=0K, it depends on the particular statistics adopted for the system and also on the dimensionality of the system. For the ideal Bose gas at T=0 K, complete Bose condensation is manifested by collapse of the dimensionality of a Hilbert space, spanned by basis vectors fsub(ν), from infinity to two. On the other hand, the dimensional effect for the ideal Fermi gas is exhibited by a change in Hilbert space structure, which is determined by the recurrants Δsub(ν) and the basis vectors fsub(ν) More specifically, the structural form of the recurrants is modified such that the relaxation function becomes more damped as D is increased. (Author)

  3. Quantization of an Ideal Monoatomic Gas

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 19; Issue 1. Quantization of an Ideal Monoatomic Gas. E Fermi. Classics Volume 19 Issue 1 January 2014 pp 82-96. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/019/01/0082-0096. Author Affiliations.

  4. Derivation of the Ideal Gas Law

    Science.gov (United States)

    Laugier, Alexander; Garai, Jozsef

    2007-01-01

    Undergraduate and graduate physics and chemistry books usually state that combining the gas laws results in the ideal gas law. Leaving the derivation to the students implies that this should be a simple task, most likely a substitution. Boyle's law, Charles's law, and the Avogadro's principle are given under certain conditions; therefore, direct…

  5. Increased body satisfaction after exposure to thin ideal children's television in young girls showing thin ideal internalisation

    NARCIS (Netherlands)

    Anschutz, D.J.; Engels, R.C.M.E.; Strien, T. van

    2012-01-01

    This study tested the direct effect of watching thin ideal children's television on body satisfaction in preadolescent girls (6–8 years old). A within-subject design was used in which girls (N = 51) were tested three times. They watched television clips in random order containing either (1) thin

  6. Monomial ideals induced by permutations avoiding patterns

    Indian Academy of Sciences (India)

    20

    supported on the order complex ∆(Σn) of a poset Σn. The Alexander dual I. [n] ... binatorially defined monomial ideals I, the standard monomials in R ...... Southeastern International Conference on Combinatorics, Graph Theory and Computing.

  7. '' Ideal Gas '' gluon plasma with medium dependent dispersion relation

    International Nuclear Information System (INIS)

    Gorenstein, M.I.

    1995-01-01

    An '' ideal gas '' model with temperature dependent particle mass is constructed for the gluon plasma equation of state. This simple model gives us an example of a system with temperature dependent effective Hamiltonian. To satisfy thermodynamical relations in these systems, standard statistical mechanics formulas have to be supplemented by special requirements which are considered in details. A self-consistent '' ideal gas '' formulation is used to describe Monte Carlo lattice data for the thermodynamical functions of SU(2) and SU(3) gluon plasma. 14 refs., 8 figs

  8. Pauli Paramagnetic Susceptibility of an Ideal Anyon Gas within Haldane Fractional Exclusion Statistics

    International Nuclear Information System (INIS)

    Qin Fang; Chen Jisheng

    2012-01-01

    The finite-temperature Pauli paramagnetic susceptibility of a three-dimensional ideal anyon gas obeying Haldane fractional exclusion statistics is studied analytically. Different from the result of an ideal Fermi gas, the susceptibility of an ideal anyon gas depends on a statistical factor g in Haldane statistics model. The low-temperature and high-temperature behaviors of the susceptibility are investigated in detail. The Pauli paramagnetic susceptibility of the two-dimensional ideal anyons is also derived. It is found that the reciprocal of the susceptibility has the similar factorizable property which is exhibited in some thermodynamic quantities in two dimensions.

  9. Dependence of ideal MHD kink and ballooning modes on plasma shape and profiles in tokamaks

    International Nuclear Information System (INIS)

    Todd, A.M.M.; Manickam, J.; Okabayashi, M.; Chance, M.S.; Grimm, R.C.; Greene, J.M.; Johnson, J.L.

    1978-08-01

    Extensive numerical studies of ideal MHD instabilities have been carried out to gain insight into the parametric dependence of critical β's in tokamaks. The large number of interrelated equilibrium quantities involved in establishing a critical β has demanded a careful, systematic survey in order to isolate this dependence. The results of this survey establish the scaling with geometrical quantities including aspect ratio, elongation, and triangularity in the parameter regimes appropriate for both current and reactor-sized plasmas. A moderate dependence on the pressure profile and a strong variation with the current profile is found. The principal result is that for aspect ratio R/a approximately equal to 3, critical β's are of the order of 2% for circular cross sections and 5% for plasmas with elongation K approximately equal to 2; somewhat higher values could be achieved with more optimal shaping. Finally, sequences of equilibria have been analyzed to compare critical β as a function of toroidal mode number n. We conclude that the infinite-n analytic ballooning theory provides a sufficient condition for ideal MHD internal mode stability. Low-n free boundary modes appear to set a lower limit

  10. [Relationship between 'ideal' cardiovascular behaviors and factors and the incidence of hypertension].

    Science.gov (United States)

    Zhang, Caifeng; Shi, Jihong; Huang, Zhe; Li, Huiying; Wei, Xiaoming; Lin, Liming; Xing, Aijun; Chen, Shuohua; Wu, Shouling

    2014-05-01

    To explore the relationship between 'ideal' cardiovascular behaviors and factors and the incidence of hypertension. A prospective cohort study including 52 133 workers who had participated in the 2006-2007 Kailuan health examination without history of cerebral infraction, myocardial infarction or hypertension but with complete data, was carried out. All workers were followed on their occurrence of hypertension. According to the AHA definition of 'ideal' cardiovascular health behaviors and factors, the cumulative incidence rates of hypertension in different groups were calculated under the life table method, and compared by Log-rank test, Cox proportional hazards regression was used to calculate the hazard rations and 95% confidence intervals for baseline behaviors and factors. The cumulative incidence rates of hypertension according 0-1, 2, 3, 4, 5-7 ideal cardiovascular health behaviors and factors were 65.72%, 59.14%, 54.59%, 50.24% and 34.22%, respectively in the 0-1, 2, 3, 4, 5-7 groups. Data from the Cox proportional hazards model showed that after adjusting for age, education level and family history of hypertension, the ones who had 2, 3, 4, 5-7 ideal cardiovascular behaviors/factors were 0.75, 0.69, 0.63, 0.36 times more than those who had 0-1 ideal behaviors. The incidence of hypertension and risk reduced along with the increase of ideal cardiovascular health behaviors and factors.

  11. Karl Jaspers on the disease entity: Kantian ideas and Weberian ideal types.

    Science.gov (United States)

    Walker, Chris

    2014-09-01

    Jaspers' nosology is indebted to Immanuel Kant's theory of knowledge. He drew the distinction of form and content from the Transcendental Analytic of Kant's Critique of Pure Reason. The distinction is universal to all knowledge, including psychopathology. Individual experience is constituted by a form or category of the Understanding to give a determinate or knowable object classified into the generic type of a real disease entity. The application of form and content is limited by the boundaries of experience. Beyond this boundary are wholes whose conception requires Ideas of reason drawn from the Transcendental Dialectic. Wholes are regulated by Ideas of reason to give an object or schema of the Idea collected into ideal types of an ideal typical disease entity. Jaspers drew ideal types from Max Weber's social theory. He anticipated that, as knowledge advanced, ideal typical disease entities would become real disease entities. By 1920, this had been the destiny of general paralysis as knowledge of its neuropathology, serology and microbiology emerged. As he presented the final edition of General Psychopathology in 1946, Jaspers was anticipating the transition of schizophrenia from ideal typical to real disease entity. Almost 70 years later, with knowledge of its aetiology still unclear, schizophrenia remains marooned as an ideal typical disease entity - still awaiting that crucial advance! © The Author(s) 2014.

  12. On multiphase negative flash for ideal solutions

    DEFF Research Database (Denmark)

    Yan, Wei; Stenby, Erling Halfdan

    2012-01-01

    simpler than the corresponding normal flash algorithm. Unlike normal flash, multiphase negative flash for ideal solutions can diverge if the feasible domain for phase amounts is not closed. This can be judged readily during the iteration process. The algorithm can also be extended to the partial negative......There is a recent interest to solve multiphase negative flash problems where the phase amounts can be negative for normal positive feed composition. Solving such a negative flash problem using successive substitution needs an inner loop for phase distribution calculation at constant fugacity...... coefficients. It is shown that this inner loop, named here as multiphase negative flash for ideal solutions, can be solved either by Michelsen's algorithm for multiphase normal flash, or by its variation which uses F−1 phase amounts as independent variables. In either case, the resulting algorithm is actually...

  13. Management of infection in myelosuppressed patients: clinical trials and common sense.

    Science.gov (United States)

    Greene, W H

    1985-01-01

    In the past fifteen years, enormous research effort has been expended in pursuit of the "ideal" approach to the management of infection in the myelosuppressed, i.e., granulocytopenic, patient. In the welter of clinical trials, some "commonsense" fundamentals have been lost or submerged, while other ideas seem to have become "modern myths." Among those commonsense approaches that should not be forgotten are the following: Granulocytopenia often precludes even the most skilled observer from assessing whether a febrile patient is truly infected. The epidemiology of infection at the local institution should be the principal determinant of the empiric antibiotic regimen in use. There is no ideal empiric antibiotic regimen. In particular, there is no absolute necessity for antipseudomonal penicillins, for aminoglycosides or for combinations of antibiotics. Some modern myths that seem to have been widely accepted without adequate data are: Antibiotic "synergism" is an essential prerequisite to a successful outcome of infection in the granulocytopenic patient. In the febrile granulocytopenic patient who responds to treatment, antibiotics should be continued until the granulocytopenia resolves. In the febrile granulocytopenic patient who does not respond to treatment, all such patients should receive amphotericin B for empiric antifungal treatment. These and other modern myths and aspects of common sense will be discussed in light of recent clinical trials.

  14. Consumer satisfaction - an unattainable ideal? | Erasmus | Journal ...

    African Journals Online (AJOL)

    Verbruikerstevredenheid, 'n na-aankoopevaluering dat 'n gekose produk aan 'n verbruiker se verwagtinge voldoen of dit oortref (Engel et al, 1995), word algemeen as die ideale uitkoms van verbruikersbesluitneming voorgehou. Verbruikerstevredenheid verlig die interne spanningstoestand (kognitiewe dissonansie) wat ...

  15. The Heat Capacity of Ideal Gases

    Science.gov (United States)

    Scott, Robert L.

    2006-01-01

    The heat capacity of an ideal gas has been shown to be calculable directly by statistical mechanics if the energies of the quantum states are known. However, unless one makes careful calculations, it is not easy for a student to understand the qualitative results. Why there are maxima (and occasionally minima) in heat capacity-temperature curves…

  16. Reduction of a family of ideals

    OpenAIRE

    Rodak, Tomasz

    2015-01-01

    In the paper we prove that there exists a simultaneous reduction of one-parameter family of $\\mathfrak{m}_{n}$-primary ideals in the ring of germs of holomorphic functions. As a corollary we generalize the result of A. P\\l{}oski \\cite{ploski} on the semicontinuity of the \\L{}ojasiewicz exponent in a multiplicity-constant deformation.

  17. Algorithms for Zero-Dimensional Ideals Using Linear Recurrent Sequences

    DEFF Research Database (Denmark)

    Neiger, Vincent; Rahkooy, Hamid; Schost, Éric

    2017-01-01

    Inspired by Faugére and Mou´s sparse FGLM algorithm, we show how using linear recurrent multi-dimensional sequences can allow one to perform operations such as the primary decomposition of an ideal, by computing of the annihilator of one or several such sequences.......Inspired by Faugére and Mou´s sparse FGLM algorithm, we show how using linear recurrent multi-dimensional sequences can allow one to perform operations such as the primary decomposition of an ideal, by computing of the annihilator of one or several such sequences....

  18. Ideal gas behavior of a strongly coupled complex (dusty) plasma.

    Science.gov (United States)

    Oxtoby, Neil P; Griffith, Elias J; Durniak, Céline; Ralph, Jason F; Samsonov, Dmitry

    2013-07-05

    In a laboratory, a two-dimensional complex (dusty) plasma consists of a low-density ionized gas containing a confined suspension of Yukawa-coupled plastic microspheres. For an initial crystal-like form, we report ideal gas behavior in this strongly coupled system during shock-wave experiments. This evidence supports the use of the ideal gas law as the equation of state for soft crystals such as those formed by dusty plasmas.

  19. Ideal gas behavior of a strongly-coupled complex (dusty) plasma

    OpenAIRE

    Oxtoby, Neil P.; Griffith, Elias J.; Durniak, Céline; Ralph, Jason F.; Samsonov, Dmitry

    2012-01-01

    In a laboratory, a two-dimensional complex (dusty) plasma consists of a low-density ionized gas containing a confined suspension of Yukawa-coupled plastic microspheres. For an initial crystal-like form, we report ideal gas behavior in this strongly-coupled system during shock-wave experiments. This evidence supports the use of the ideal gas law as the equation of state for soft crystals such as those formed by dusty plasmas.

  20. Study of Optimal Replacement of Thyroxine in the ElDerly (SORTED): protocol for a mixed methods feasibility study to assess the clinical utility of lower dose thyroxine in elderly hypothyroid patients: study protocol for a randomized controlled trial.

    Science.gov (United States)

    Wilkes, Scott; Pearce, Simon; Ryan, Vicky; Rapley, Tim; Ingoe, Lorna; Razvi, Salman

    2013-03-22

    The population of the UK is ageing. There is compelling evidence that thyroid stimulating hormone distribution levels increase with age. Currently, in UK clinical practice elderly hypothyroid patients are treated with levothyroxine to lower their thyroid stimulating hormone levels to a standard non-age-related range. Evidence suggests that mortality is negatively associated with thyroid stimulating hormone levels. We report the protocol of a feasibility study working towards a full-scale randomized controlled trial to test whether lower dose levothyroxine has beneficial cardiovascular outcomes in the oldest old. SORTED is a mixed methods study with three components: SORTED A: A feasibility study of a dual-center single-blinded randomized controlled trial of elderly hypothyroid patients currently treated with levothyroxine. Patients will be recruited from 20 general practices and two hospital trust endocrine units in Northumberland, Tyne and Wear. Target recruitment of 50 elderly hypothyroid patients currently treated with levothyroxine, identified in both primary and secondary care settings. Reduced dose of levothyroxine to achieve an elevated serum thyroid stimulating hormone (target range 4.1 to 8.0 mU/L) versus standard levothyroxine replacement (target range 0.4 to 4.0 mU/L). Using random permuted blocks, in a ratio of 1:1, randomization will be carried out by Newcastle Clinical Trials Unit. Study feasibility (recruitment and retention rates and medication compliance), acceptability of the trial design, assessment of mobility and falls risk, and change in cardiovascular risk factors. Qualitative study using in-depth interviews to understand patients' willingness to take part in a randomized controlled trial and participants' experience of the intervention. Retrospective cohort study of 400 treated hypothyroid patients aged 80 years or over registered in 2008 in primary care practices, studying their 4-year cardiovascular outcomes to inform the power of SORTED

  1. Qualifications of an Ideal Teacher According to Social Studies Preservice Teachers

    Science.gov (United States)

    Gencturk, Ebru; Akbas, Yavuz; Kaymakci, Selahattin

    2012-01-01

    In this study, the question of what kind of qualifications an ideal social studies teacher has tried to be investigated. For this purpose, freshman social studies preservice teachers' perceptions about the concept of "ideal teacher" were explored. This study was designed with document analysis, one of the methods of qualitative approach.…

  2. The Noborder Movement: Interpersonal Struggle with Political Ideals

    Directory of Open Access Journals (Sweden)

    Leslie Gauditz

    2017-09-01

    Full Text Available Over the last decade, self-organized refugee protests in Europe have increased. One strand of activism in Europe, noborder, involves a transnational network of people who are heterogeneous with regards to legal status, race, or individual history of migration, but who share decolonial, anti-capitalist ideals that criticize the nation-state. Noborder activists embrace prefigurative strategies, which means enacting political ideals in their everyday life. This is why this article asks: How do noborder activists try to meet their political ideals in their everyday practices, and what effects do these intentions entail? Noborder practices take place at the intersection of self-organization as a reference to migrants’ legal status or identity, on the one hand, and self-organization as anti-hierarchical forms of anarchist-autonomous organization, on the other. On the basis of empirical findings of a multi-sited ethnography in Germany and Greece, this article conceptualizes that noborder creates a unique space for activists to meet in which people try to work productively through conflicts they see as being produced by a global system of inequalities. This demanding endeavor involves social pressure to self-reflect and to transform interpersonal relationships. Broader society could learn from such experiences to build more inclusive, heterogeneous communities.

  3. No Surgical Innovation Without Evaluation: Evolution and Further Development of the IDEAL Framework and Recommendations.

    Science.gov (United States)

    Hirst, Allison; Philippou, Yiannis; Blazeby, Jane; Campbell, Bruce; Campbell, Marion; Feinberg, Joshua; Rovers, Maroeska; Blencowe, Natalie; Pennell, Christopher; Quinn, Tom; Rogers, Wendy; Cook, Jonathan; Kolias, Angelos G; Agha, Riaz; Dahm, Philipp; Sedrakyan, Art; McCulloch, Peter

    2018-04-24

    To update, clarify, and extend IDEAL concepts and recommendations. New surgical procedures, devices, and other complex interventions need robust evaluation for safety, efficacy, and effectiveness. Unlike new medicines, there is no internationally agreed evaluation pathway for generating and analyzing data throughout the life cycle of surgical innovations. The IDEAL Framework and Recommendations were designed to provide this pathway and they have been used increasingly since their introduction in 2009. Based on a Delphi survey, expert workshop and major discussions during IDEAL conferences held in Oxford (2016) and New York (2017), this article updates and extends the IDEAL Recommendations, identifies areas for future research, and discusses the ethical problems faced by investigators at each IDEAL stage. The IDEAL Framework describes 5 stages of evolution for new surgical therapeutic interventions-Idea, Development, Exploration, Assessment, and Long-term Study. This comprehensive update proposes several modifications. First, a "Pre-IDEAL" stage describing preclinical studies has been added. Second we discuss potential adaptations to expand the scope of IDEAL (originally designed for surgical procedures) to accommodate therapeutic devices, through an IDEAL-D variant. Third, we explicitly recognise the value of comprehensive data collection through registries at all stages in the Framework and fourth, we examine the ethical issues that arise at each stage of IDEAL and underpin the recommendations. The Recommendations for each stage are reviewed, clarified and additional detail added. The intention of this article is to widen the practical use of IDEAL by clarifying the rationale for and practical details of the Recommendations. Additional research based on the experience of implementing these Recommendations is needed to further improve them.

  4. Participant verification: prevention of co-enrolment in clinical trials in South Africa.

    Science.gov (United States)

    Harichund, C; Haripersad, K; Ramjee, R

    2013-05-15

    As KwaZulu-Natal Province is the epicentre of the HIV epidemic in both South Africa (SA) and globally, it is an ideal location to conduct HIV prevention and therapeutic trials. Numerous prevention trials are currently being conducted here; the potential for participant co-enrolment may compromise the validity of these studies and is therefore of great concern. To report the development and feasibility of a digital, fingerprint-based participant identification method to prevent co-enrolment at multiple clinical trial sites. The Medical Research Council (MRC) HIV Prevention Research Unit (HPRU) developed the Biometric Co-enrolment Prevention System (BCEPS), which uses fingerprint-based biometric technology to identify participants. A trial website was used to determine the robustness and usability of the system. After successful testing, the BCEPS was piloted in July 2010 across 7 HPRU clinical research sites. The BCEPS was pre-loaded with study names and clinical trial sites, with new participant information loaded at first visit to a trial site. We successfully implemented the BCEPS at the 7 HPRU sites. Using the BCEPS, we performed real-time 'flagging' of women who were already enrolled in another study as they entered a trial at an HPRU site and, where necessary, excluded them from participation on site. This system has promise in reducing co-enrolment in clinical trials and represents a valuable tool for future implementation by all groups conducting trials. The MRC is currently co-ordinating this effort with clinical trial sites nationally.

  5. Exploring the Professional Ideals of Christian Teachers from Conservative Protestant Schools in the Netherlands

    Science.gov (United States)

    Boele-de Bruin, H. L.; de Muynck, A.

    2018-01-01

    Professional ideals arise from personal worldviews and specify teachers' professional identities. This study aimed to explore how faith is present in the professional ideals of Christian teachers. The professional ideals of 107 Dutch teachers from conservative Protestant primary and secondary schools were explored using an open-ended…

  6. The development and validation of the Body-Image Ideals Questionnaire.

    Science.gov (United States)

    Cash, T F; Szymanski, M L

    1995-06-01

    The Body-Image Ideals Questionnaire (BIQ) was developed as a unique attitudinal body-image assessment that considers one's perceived discrepancy from and degree of investment in personal ideals on multiple physical attributes. Reliability and validity of the 20-item instrument were examined for a sample of 284 college women. The results indicated that the BIQ consists of two relatively distinct and internally consistent Discrepancy and Importance subscales, as well as their multiplicative composite. The subscales' respective convergent validities vis-à-vis extant body-image measures and specific facets of personality (i.e., public self-consciousness and perfectionism) and psychosocial adjustment (i.e., social anxiety, depression, and eating disturbance) were confirmed. Evidence also supported the incremental validity of multiple self-ideal discrepancies. Effects due to socially desirable responding were inconsequential. Directions for needed basic and clinical research were identified.

  7. CYP7A1-rs3808607 and APOE isoform associate with LDL cholesterol lowering after plant sterol consumption in a randomized clinical trial.

    Science.gov (United States)

    MacKay, Dylan S; Eck, Peter K; Gebauer, Sarah K; Baer, David J; Jones, Peter Jh

    2015-10-01

    The benefits of plant sterols (PSs) for cholesterol lowering are hampered by large heterogeneity across individuals, potentially because of genetic polymorphisms. We investigated the impact of candidate genetic variations on cholesterol response to PSs in a trial that recruited individuals with high or low endogenous cholesterol synthesis, estimated by lathosterol to cholesterol (L:C) ratio. Mildly hypercholesterolemic adults preselected as possessing either high endogenous cholesterol synthesis (n = 24; mean ± SEM: L:C ratio = 2.03 ± 0.39 μmol/mmol) or low endogenous cholesterol synthesis (n = 39; mean ± SEM: L:C ratio = 0.99 ± 0.28 μmol/mmol) consumed 2 g PS/d or a placebo for 28 d by using a dual-center, single-blind, randomized crossover design. Cholesterol synthesis and change in cholesterol absorption were measured with stable isotopic tracers. Candidate single-nucleotide polymorphisms and apolipoprotein E (APOE) isoform were assessed by TaqMan genotyping assay. The cholesterol fractional synthesis rate was higher (P cholesterol synthesis (mean ± SEM: placebo: 9.16% ± 0.47%; PSs: 9.74% ± 0.47%) than in participants with low endogenous cholesterol synthesis (mean ± SEM placebo: 5.72% ± 0.43%; PS: 7.10% ± 0.43%). Low-density lipoprotein (LDL) cholesterol lowering in response to PSs was associated with individuals' genotypes. Cholesterol 7 alpha-hydroxylase (CYP7A1-rs3808607) T/T homozygotes showed no LDL cholesterol lowering (mean ± SEM: -0.05 ± 0.07 mmol/L, P = 0.9999, n = 20), whereas the presence of the G-allele associated with LDL cholesterol response in a dose-dependent fashion (mean ± SEM G/T: -0.22 ± 0.06 mmol/L, P = 0.0006, n = 35; G/G: -0.46 ± 0.12 mmol/L, P = 0.0009, n = 8). Similarly, APOE ɛ3 carriers (mean ± SEM: -0.13 ± 0.05 mmol/L, P = 0.0370, n = 40) responded less than APOE ɛ4 carriers (mean ± SEM: -0.31 ± 0.07 mmol/L, P LDL cholesterol lowering. Cholesterol absorption decreased as a result of PS consumption, but this

  8. On the Maximal Ideals of Non-Zero-Symmetric Near-Rings and of ...

    African Journals Online (AJOL)

    Keywords: ideals, near-rings, algebra, composition algebras, polynomial functions, Ω-groups, maximal ideals, Brown-McCoy radical, operations, polynomials, primal algebras, ordinary polynomial rings, skew polynomial rings, semigroup rings, Banach, banach space, Pettis, Pettis integrable, complete, congruences, ...

  9. From the Civil War to 9/11: Democracy and the Right to a Fair Trial

    Science.gov (United States)

    Marcus, Alan S.

    2011-01-01

    In the United States, the right to a fair trial is protected by the Constitution. The ideal of justice is a critical underpinning of the democracy. However, while the United States is a model of an honorable and just court system most of the time, our constitutional rights are occasionally stretched or broken. The rationale is often national…

  10. Opportunity for Realizing Ideal Computing System using Cloud Computing Model

    OpenAIRE

    Sreeramana Aithal; Vaikunth Pai T

    2017-01-01

    An ideal computing system is a computing system with ideal characteristics. The major components and their performance characteristics of such hypothetical system can be studied as a model with predicted input, output, system and environmental characteristics using the identified objectives of computing which can be used in any platform, any type of computing system, and for application automation, without making modifications in the form of structure, hardware, and software coding by an exte...

  11. Comparison of reporting phase I trial results in ClinicalTrials.gov and matched publications.

    Science.gov (United States)

    Shepshelovich, D; Goldvaser, H; Wang, L; Abdul Razak, A R; Bedard, P L

    2017-12-01

    Background Data on completeness of reporting of phase I cancer clinical trials in publications are lacking. Methods The ClinicalTrials.gov database was searched for completed adult phase I cancer trials with reported results. PubMed was searched for matching primary publications published prior to November 1, 2016. Reporting in primary publications was compared with the ClinicalTrials.gov database using a 28-point score (2=complete; 1=partial; 0=no reporting) for 14 items related to study design, outcome measures and safety profile. Inconsistencies between primary publications and ClinicalTrials.gov were recorded. Linear regression was used to identify factors associated with incomplete reporting. Results After a review of 583 trials in ClinicalTrials.gov , 163 matching primary publications were identified. Publications reported outcomes that did not appear in ClinicalTrials.gov in 25% of trials. Outcomes were upgraded, downgraded or omitted in publications in 47% of trials. The overall median reporting score was 23/28 (interquartile range 21-25). Incompletely reported items in >25% publications were: inclusion criteria (29%), primary outcome definition (26%), secondary outcome definitions (53%), adverse events (71%), serious adverse events (80%) and dates of study start and database lock (91%). Higher reporting scores were associated with phase I (vs phase I/II) trials (ppublication in journals with lower impact factor (p=0.004). Conclusions Reported results in primary publications for early phase cancer trials are frequently inconsistent or incomplete compared with ClinicalTrials.gov entries. ClinicalTrials.gov may provide more comprehensive data from new cancer drug trials.

  12. An ideal sealed source life-cycle

    International Nuclear Information System (INIS)

    Tompkins, Joseph Andrew

    2009-01-01

    we have today. This regulation created a new regulatory framework seen as promising at the time. However, now they recognize that, despite the good intentions, the NIJWP/85 has not solved any source disposition problems. The answer to these sealed source disposition problems is to adopt a philosophy to correct these regulatory issues, determine an interim solution, execute that solution until there is a minimal backlog of sources to deal with, and then let the mechanisms they have created solve this problem into the foreseeable future. The primary philosophical tenet of the ideal sealed source life cycle follows. You do not allow the creation (or importation) of any source whose use cannot be justified, which cannot be affordably shipped, or that does not have a well-delinated and affordable disposition pathway. The path forward dictates that we fix the problem by embracing the Ideal Source Life cycle. In figure 1, we can see some of the elements of the ideal source life cycle. The life cycle is broken down into four portions, manufacture, use, consolidation, and disposition. These four arbitrary elements allow them to focus on the ideal life cycle phases that every source should go through between manufacture and final disposition. As we examine the various phases of the sealed source life cycle, they pick specific examples and explore the adoption of the ideal life cycle model.

  13. Specific heats of degenerate ideal gases

    OpenAIRE

    Caruso, Francisco; Oguri, Vitor; Silveira, Felipe

    2017-01-01

    From arguments based on Heisenberg's uncertainty principle and Pauli's exclusion principle, the molar specific heats of degenerate ideal gases at low temperatures are estimated, giving rise to values consistent with the Nerst-Planck Principle (third law of Thermodynamics). The Bose-Einstein condensation phenomenon based on the behavior of specific heat of massive and non-relativistic boson gases is also presented.

  14. American Citizens’ Views of an Ideal Pig Farm

    Science.gov (United States)

    Sato, Patrycia; Hötzel, Maria J.; von Keyserlingk, Marina A.G.

    2017-01-01

    Simple Summary The public, who also make up the largest proportion of consumers of animal products, often criticize farm animal industries in regards to their care and handling of farm animals. The U.S. swine industry has not been exempt from such criticisms. The aim of this study was to explore the views of the people not affiliated with the swine industry on what they perceived to be the ideal pig/pork farm, and their associated reasons. Through an online survey, participants were invited to respond to the following open-ended question: “What do you consider to be an ideal pig/pork farm and why are these characteristics important to you?”. Respondents considered animal care, profitability, farm size, compliance with sanitary, environmental rules and regulations, farm cleanliness and sanitary standards, and workers’ rights and welfare important, but also raised concerns relating to pigs’ quality of life including space to move, feeding, contact with outdoors or nature, absence of pain, suffering and mistreatment. Perspectives were also raised regarding the ideal farm as a profitable business operation, clean, and with optimal sanitary conditions. Respondents also emphasized naturalness, frequently stating that pigs should have access to the outdoors, and rejected the use of hormones, antibiotics, and other chemicals for the purposes of increasing production. Abstract Food animal production practices are often cited as having negative animal welfare consequences. The U.S. swine industry has not been exempt from such criticisms. Little is known, however, about how lay citizens who are not actively engaged in agricultural discussions, think about swine production. Thus, the aim of this study was to explore the views of people not affiliated with the swine industry on what they perceived to be the ideal pig/pork farm, and their associated reasons. Through an online survey, participants were invited to respond to the following open-ended question: “What do

  15. Nutritional status and the influence of TV consumption on female body size ideals in populations recently exposed to the media.

    Science.gov (United States)

    Jucker, Jean-Luc; Thornborrow, Tracey; Beierholm, Ulrik; Burt, D Michael; Barton, Robert A; Evans, Elizabeth H; Jamieson, Mark A; Tovée, Martin J; Boothroyd, Lynda G

    2017-08-16

    Television consumption influences perceptions of attractive female body size. However, cross-cultural research examining media influence on body ideals is typically confounded by differences in the availability of reliable and diverse foodstuffs. 112 participants were recruited from 3 Nicaraguan villages that differed in television consumption and nutritional status, such that the contribution of both factors could be revealed. Participants completed a female figure preference task, reported their television consumption, and responded to several measures assessing nutritional status. Communities with higher television consumption and/or higher nutritional status preferred thinner female bodies than communities with lower television consumption and/or lower nutritional status. Bayesian mixed models estimated the plausible range of effects for television consumption, nutritional status, and other relevant variables on individual preferences. The model explained all meaningful differences between our low-nutrition villages, and television consumption, after sex, was the most likely of these predictors to contribute to variation in preferences (probability mass >95% when modelling only variables with zero-order associations with preferences, but only 90% when modelling all possible predictors). In contrast, we found no likely link with nutritional status. We thus found evidence that where media access and nutritional status are confounded, media is the more likely predictor of body ideals.

  16. Lifestyle constraints, not inadequate nutrition education, cause gap between breakfast ideals and realities among Japanese in Tokyo.

    Science.gov (United States)

    Melby, Melissa K; Takeda, Wakako

    2014-01-01

    Japanese public health nutrition often promotes 'traditional' cuisine. In-depth interviews with 107 Japanese adults were conducted in Tokyo from 2009 to 2011, using free-listing methods to examine dietary ideals and realities to assess the extent to which realities reflect inadequate nutrition education or lifestyle constraints. Ideal-reality gaps were widest for breakfast. Most people reported Japanese ideals: rice and miso soup were prototypical foods. However, breakfast realities were predominantly western (bread-based). While those aged 40-59 were more likely to hold Japanese ideals (P=0.063), they were less likely to achieve them (P=0.007). All those reporting western ideals achieved them on weekdays, while only 64% of those with Japanese ideals achieved them (Pachievement of Japanese ideals were positively correlated with proportion of cooking-related housework, and negatively correlated with living standard and income. Ideal menu content was in line with current Japanese nutrition advice, suggesting that more nutrition education may not change dietary ideals or behavior. Participant-reported reasons for ideal-reality discordance demonstrate that work-life balance issues, especially lack of time and family structure/life rhythm, are the largest obstacles to the attainment of dietary ideals. People reporting 'no time' as a primary reason for ideal-reality gaps were less likely to achieve their Japanese ideals (odds ratio=0.212). Time realities of people's lives may undermine educational efforts promoting Japanese breakfasts. When dietary reality/behavior departs from guidelines, it is often assumed that people lack knowledge. If ideals are in line with dietary guidelines, then lack of knowledge is not the likely cause and nutrition education is not the optimal solution. By asking people about the reasons for gaps between their ideals and realities, we can identify barriers and design more effective policies and programs to achieve dietary ideals. Copyright

  17. Qualities of Ideal Teacher Educators

    Directory of Open Access Journals (Sweden)

    Nihal Tunca

    2015-04-01

    Full Text Available Abstract Generally, the relationship between the teacher educators' qualities and the quality of teacher education has not been discussed extensively in the literature. At the same time, various studies can be found in the eastern literature examining the characteristics of faculty members at the education faculties. The effect of teacher educators over teacher candidates has not been explored, and in this sense, there is limited number of studies examining faculty members at education faculties in Turkey. Mostly employing quantitative research designs, these studies have focused on faculty members in terms of various characteristics However, which qualities that faculty members should have as a whole have not been studied. However, faculty members, as well as teachers who are a matter of debate in terms of the qualities they are supposed to have should be examined in research studies. In this context, this study aims to identify the qualities that an ideal teacher educator should have from the perspective of education faculty students as future teachers. The current research is a qualitative study in phenomenology design. The participants of the study are third and fourth year 214 pre-service teachers from the departments of Science and Technology Teaching, Pre-School Teacher Education, Classroom Teacher Education, Social Studies Teaching and Turkish Language Teaching. Criterion sampling was used for participant selection. The data gathering tool consisted of an open-ended question that would reveal the qualities that an ideal teacher educator should have based on teacher candidates’ views. Junior and senior teacher candidates’ views were asked and the data were analyzed according to content analysis approach. As a result, the qualities that an ideal teacher educator should have been gathered under five main themes including ‘professional roles and responsibilities, professional values, personal characteristics, professional ethic

  18. Narrowing beam-walking is a clinically feasible approach for assessing balance ability in lower-limb prosthesis users.

    Science.gov (United States)

    Sawers, Andrew; Hafner, Brian J

    2018-05-08

    Challenging clinical balance tests are needed to expose balance deficits in lower-limb prost-hesis users. This study examined whether narrowing beam-walking could overcome conceptual and practical limitations identified in fixed-width beam-walking. Cross-sectional. Unilateral lower-limb prosthesis users. Participants walked 10 times along a low, narrowing beam. Performance was quantified using the normalized distance walked. Heuristic rules were applied to determine whether the narrowing beam task was "too easy," "too hard," or "appropriately challenging" for each participant. Linear regression and Bland-Altman plots were used to determine whether combinations of the first 5 trials could predict participants' stable beam-walking performance. Forty unilateral lower-limb prosthesis users participated. Narrowing beam-walking was appropriately challenging for 98% of participants. Performance stabilized for 93% of participants within 5 trials, while 62% were stable across all trials. The mean of trials 3-5 accurately predicted stable performance. A clinical narrowing beam-walking test is likely to challenge a range of lower-limb prosthesis users, have minimal administrative burden, and exhibit no floor or ceiling effects. Narrowing beam-walking is therefore a clinically viable method to evaluate lower-limb prosthesis users' balance ability, but requires psychometric testing before it is used to assess fall risk.

  19. Ideal family size in a rural Tswana population | De Villiers | South ...

    African Journals Online (AJOL)

    A questionnaire was used to discover what 350 rural Tswanas believed the ideal number of children to be; results were tabulated according to age and sex. It appears· that older people tend to want more children and, more surprisingly, that men and women agree on the ideal number of children in a family; this is contrary to ...

  20. Toward an Ideal Senior High School Governance Structure.

    Science.gov (United States)

    Treslan, D. L.

    1979-01-01

    This paper delineates six attributes of an ideal high school governance structure: respect, freedom, rationality, flexibility, equality, and involvement of staff and students in the decision-making process. (Author/SJL)

  1. Ideal for Whom? A Cultural Analysis of Ideal Worker Norms in Higher Education and Student Affairs Graduate Programs

    Science.gov (United States)

    Sallee, Margaret W.

    2016-01-01

    This chapter explores the consequences of ideal worker norms for graduate student-parents in higher education and student affairs programs. Using Schein's (2004) levels of culture as a conceptual lens, this chapter considers the ways that programmatic structures and interactions with faculty and peers reflect and reproduce a culture across…

  2. Ideal and conventional feedback systems for RWM suppression

    International Nuclear Information System (INIS)

    Pustovitov, V.D.

    2002-01-01

    Feedback suppression of resistive wall modes (RWM) is studied analytically using a model based on a standard cylindrical approximation. Two feedback systems are compared: 'ideal', creating only the field necessary for RMW suppression, and 'conventional', like that used in the DIII-D tokamak and considered as a candidate for ITER. The widespread opinion that the feedback with poloidal sensors is better than that with radial sensors is discussed. It is shown that the 'conventional' feedback with radial sensors can be effective only in a limited range, while using the input signal from internal poloidal sensors allows easy fulfilment of the stability criterion. This is a property of the 'conventional' feedback, but the 'ideal' feedback would stabilise RWM in both cases. (author)

  3. Towards an ideal preconditioner for linearized Navier-Stokes problems

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, M.F. [Univ. of Bristol (United Kingdom)

    1996-12-31

    Discretizing certain linearizations of the steady-state Navier-Stokes equations gives rise to nonsymmetric linear systems with indefinite symmetric part. We show that for such systems there exists a block diagonal preconditioner which gives convergence in three GMRES steps, independent of the mesh size and viscosity parameter (Reynolds number). While this {open_quotes}ideal{close_quotes} preconditioner is too expensive to be used in practice, it provides a useful insight into the problem. We then consider various approximations to the ideal preconditioner, and describe the eigenvalues of the preconditioned systems. Finally, we compare these preconditioners numerically, and present our conclusions.

  4. Impact of managed care on cancer trial enrollment.

    Science.gov (United States)

    Gross, C P; Krumholz, H M

    2005-06-01

    To determine the relationship between managed care market activity and cancer trial enrollment. Trial participant data were obtained from the National Cancer Institute. Participants in cooperative group trials of breast, colorectal, lung, or prostate cancer during the years 1996 through 2001 were assigned to counties based on their zip code of residence. Linear regression was used to determine the relationship between county enrollment rate and two measures of county managed care activity (penetration and index of competition [IOC]), adjusting for other county characteristics. In bivariate analysis, there was a strong inverse correlation between trial enrollment rate and IOC (r = -0.23; P penetration, proportion uninsured, and other county characteristics. Counties in the lowest quartile of managed care penetration tended to have lower enrollment rates than the remaining counties (r = -0.05; P = .048), while counties in the second, third, and fourth quartiles of penetration all had similar enrollment rates to one another. Cancer trial enrollment rates were suboptimal across all counties, and counties with higher levels of managed care competition had significantly lower enrollment rates. The relationship between managed care penetration and trial enrollment was less consistent. Future efforts to enhance trial participation should address the potential negative influence of market factors.

  5. Ideal gender identity related to parent images and locus of control: Jungian and social learning perspectives.

    Science.gov (United States)

    Shimoda, Hiroko; Keskinen, Soili

    2004-06-01

    In this research, we wanted to clarify how gender images are different or invariant and related to parents, attributes, and the attitude of controlling life (locus of control) in two cultural contexts, Japan and Finland. For this purpose, students' ideal gender images, consisting of ideal mother, female, father and male images, and parents' similarity to the four ideal gender images were studied in 135 Japanese and 119 Finnish university students. Major findings were (a) Japanese students' ideal gender images were more stereotypic than those of Finnish students; (b) students' ideal mother image and parents' similarity to the ideal mother image were related only to their sex, which supports Jung's theory; (c) students socially learned other ideal gender images, but these did not fit with expectation from social learning theory; (d) Japanese students' mothers are models or examples of gender images, but Finnish male students did not seem to base their ideal gender images on their parents. Implication of measures was discussed.

  6. Dominating sets of the comaximal and ideal-based zero-divisor ...

    African Journals Online (AJOL)

    Let R be a commutative ring with nonzero identity, and let I be an ideal of R. The ideal-based zero-divisor graph of R, denoted by ΓI (R), is the graph whose vertices are the set {x ∈ R \\ I| xy ∈ I for some y ∈ R \\ I} and two distinct vertices x and y are adjacent if and only if xy ∈ I. Define the comaximal graph of R, denoted by ...

  7. Do the Particles of an Ideal Gas Collide?

    Science.gov (United States)

    Lesk, Arthur M.

    1974-01-01

    Describes the collisional properties as a logically essential component of the ideal gas model since an actual intraparticle process cannot support observable anisotropic velocity distributions without collisions taken into account. (CC)

  8. Prerequisites of ideal safety-critical organizations

    International Nuclear Information System (INIS)

    Takeuchi, Michiru; Hikono, Masaru; Matsui, Yuko; Goto, Manabu; Sakuda, Hiroshi

    2013-01-01

    This study explores the prerequisites of ideal safety-critical organizations, marshalling arguments of 4 areas of organizational research on safety, each of which has overlap: a safety culture, high reliability organizations (HROs), organizational resilience, and leadership especially in safety-critical organizations. The approach taken in this study was to retrieve questionnaire items or items on checklists of the 4 research areas and use them as materials of abduction (as referred to in the KJ method). The results showed that the prerequisites of ideal safety-oriented organizations consist of 9 factors as follows: (1) The organization provides resources and infrastructure to ensure safety. (2) The organization has a sharable vision. (3) Management attaches importance to safety. (4) Employees openly communicate issues and share wide-ranging information with each other. (5) Adjustments and improvements are made as the organization's situation changes. (6) Learning activities from mistakes and failures are performed. (7) Management creates a positive work environment and promotes good relations in the workplace. (8) Workers have good relations in the workplace. (9) Employees have all the necessary requirements to undertake their own functions, and act conservatively. (author)

  9. The predictive validity of ideal partner preferences: a review and meta-analysis.

    Science.gov (United States)

    Eastwick, Paul W; Luchies, Laura B; Finkel, Eli J; Hunt, Lucy L

    2014-05-01

    A central element of interdependence theory is that people have standards against which they compare their current outcomes, and one ubiquitous standard in the mating domain is the preference for particular attributes in a partner (ideal partner preferences). This article reviews research on the predictive validity of ideal partner preferences and presents a new integrative model that highlights when and why ideals succeed or fail to predict relational outcomes. Section 1 examines predictive validity by reviewing research on sex differences in the preference for physical attractiveness and earning prospects. Men and women reliably differ in the extent to which these qualities affect their romantic evaluations of hypothetical targets. Yet a new meta-analysis spanning the attraction and relationships literatures (k = 97) revealed that physical attractiveness predicted romantic evaluations with a moderate-to-strong effect size (r = ∼.40) for both sexes, and earning prospects predicted romantic evaluations with a small effect size (r = ∼.10) for both sexes. Sex differences in the correlations were small (r difference = .03) and uniformly nonsignificant. Section 2 reviews research on individual differences in ideal partner preferences, drawing from several theoretical traditions to explain why ideals predict relational evaluations at different relationship stages. Furthermore, this literature also identifies alternative measures of ideal partner preferences that have stronger predictive validity in certain theoretically sensible contexts. Finally, a discussion highlights a new framework for conceptualizing the appeal of traits, the difference between live and hypothetical interactions, and the productive interplay between mating research and broader psychological theories.

  10. Ontological Choices and the Value-Free Ideal

    NARCIS (Netherlands)

    Ludwig, D.J.

    2015-01-01

    The aim of this article is to argue that ontological choices in scientific practice undermine common formulations of the value-free ideal in science. First, I argue that the truth values of scientific statements depend on ontological choices. For example, statements about entities such as species,

  11. Ontological Choices and the Value-Free Ideal

    NARCIS (Netherlands)

    Ludwig, David

    2016-01-01

    The aim of this article is to argue that ontological choices in scientific practice undermine common formulations of the value-free ideal in science. First, I argue that the truth values of scientific statements depend on ontological choices. For example, statements about entities such as species,

  12. Collective excitations of harmonically trapped ideal gases

    NARCIS (Netherlands)

    Van Schaeybroeck, B.; Lazarides, A.

    2009-01-01

    We theoretically study the collective excitations of an ideal gas confined in an isotropic harmonic trap. We give an exact solution to the Boltzmann-Vlasov equation; as expected for a single-component system, the associated mode frequencies are integer multiples of the trapping frequency. We show

  13. Dynamic optimization of a dead-end filtration trajectory: non-ideal cake filtration

    NARCIS (Netherlands)

    Blankert, B.; Kattenbelt, C.; Betlem, Bernardus H.L.; Roffel, B.

    2007-01-01

    A control strategy aimed at minimizing energy consumption is formulated for non-ideal dead-end cake filtration with an inside-out hollow fiber ultrafiltration membrane system. The non-ideal behavior was assumed to originate from cake compression, non-linear cake resistance and a variable pump

  14. Ideal gas thermodynamic properties for the phenyl, phenoxy, and o-biphenyl radicals

    Science.gov (United States)

    Burcat, A.; Zeleznik, F. J.; Mcbride, B. J.

    1985-01-01

    Ideal gas thermodynamic properties of the phenyl and o-biphenyl radicals, their deuterated analogs and the phenoxy radical were calculated to 5000 K using estimated vibrational frequencies and structures. The ideal gas thermodynamic properties of benzene, biphenyl, their deuterated analogs and phenyl were also calculated.

  15. Coming close to the ideal alternative: The concordant-ranks strategy

    Directory of Open Access Journals (Sweden)

    Neda Kerimi

    2011-04-01

    Full Text Available We present the Concordant-Ranks (CR strategy that decision makers use to quickly find an alternative that is proximate to an ideal alternative in a multi-attribute decision space. CR implies that decision makers prefer alternatives that exhibit concordant ranks between attribute values and attribute weights. We show that, in situations where the alternatives are equal in multi-attribute utility (MAU, minimization of the weighted Euclidean distance (WED to an ideal alternative implies the choice of a CR alternative. In two experiments, participants chose among, as well as evaluated, alternatives that were constructed to be equal in MAU. In Experiment 1, four alternatives were designed in such a way that the choice of each alternative would be consistent with one particular choice strategy, one of which was the CR strategy. In Experiment 2, participants were presented with a CR alternative and a number of arbitrary alternatives. In both experiments, participants tended to choose the CR alternative. The CR alternative was on average evaluated as more attractive than other alternatives. In addition, measures of WED, between given alternatives and the ideal alternative, by and large agreed with the preference order for choices and attractiveness evaluations of the different types of alternatives. These findings indicate that both choices and attractiveness evaluations are guided by proximity of alternatives to an ideal alternative.

  16. Concordance: Design Ideal for Facilitating Situated Negotiations in Out-of-clinic Healthcare

    DEFF Research Database (Denmark)

    Bagalkot, Naveen L.; Gronvall, Erik; Sokoler, Tomas

    2014-01-01

    Healthcare HCI research has explored various designs that encourage people to follow prescribed treatments, mostly adopting compliance and adherence as design ideals. However, within the medical sciences the notion of concordance also exists. Concordance promotes negotiation between the patient...... and healthcare professional for forging a therapeutic alliance. However, the HCI community has still not adopted concordance as a design ideal. This paper revisits four old design-cases to explore the role of concordance in out-of-clinic healthcare. We argue that concordance, as a design ideal, can guide new...... designs that promote a more active patient-role both at the clinic and beyond....

  17. Abanico de Gröbner y politopo de estados de un ideal

    OpenAIRE

    Rubio de Nicolás, Cristina

    2017-01-01

    Este trabajo tiene como objetivo hacer un estudio introductorio sobre los ideales iniciales respecto de órdenes monomiales de un ideal I del anillo k[x1;..., xm]. En él se enuncian algunos resultados técnicos sobre bases de Gröbner y geometría poliedral, necesarios para su desarrollo. En el trabajo se comprueba que existe un número finito de tales ideales iniciales, y se define el abanico de Gröbner de I, GF(I). Este abanico es un complejo poliedral de conos en el cual cada cono se correspond...

  18. Inclusion of Minority Patients in Breast Cancer Clinical Trials: The Role of the Clinical Trial Environment

    National Research Council Canada - National Science Library

    Kaplan, Celia P

    2007-01-01

    .... While inroads to increasing minority inclusion in breast cancer clinical trials have been made, recent reports continue to demonstrate lower enrollment among African Americans, Asian Americans...

  19. Statistical analysis plan for the Pneumatic CompREssion for PreVENting Venous Thromboembolism (PREVENT) trial: a study protocol for a randomized controlled trial.

    Science.gov (United States)

    Arabi, Yaseen; Al-Hameed, Fahad; Burns, Karen E A; Mehta, Sangeeta; Alsolamy, Sami; Almaani, Mohammed; Mandourah, Yasser; Almekhlafi, Ghaleb A; Al Bshabshe, Ali; Finfer, Simon; Alshahrani, Mohammed; Khalid, Imran; Mehta, Yatin; Gaur, Atul; Hawa, Hassan; Buscher, Hergen; Arshad, Zia; Lababidi, Hani; Al Aithan, Abdulsalam; Jose, Jesna; Abdukahil, Sheryl Ann I; Afesh, Lara Y; Dbsawy, Maamoun; Al-Dawood, Abdulaziz

    2018-03-15

    The Pneumatic CompREssion for Preventing VENous Thromboembolism (PREVENT) trial evaluates the effect of adjunctive intermittent pneumatic compression (IPC) with pharmacologic thromboprophylaxis compared to pharmacologic thromboprophylaxis alone on venous thromboembolism (VTE) in critically ill adults. In this multicenter randomized trial, critically ill patients receiving pharmacologic thromboprophylaxis will be randomized to an IPC or a no IPC (control) group. The primary outcome is "incident" proximal lower-extremity deep vein thrombosis (DVT) within 28 days after randomization. Radiologists interpreting the lower-extremity ultrasonography will be blinded to intervention allocation, whereas the patients and treating team will be unblinded. The trial has 80% power to detect a 3% absolute risk reduction in the rate of proximal DVT from 7% to 4%. Consistent with international guidelines, we have developed a detailed plan to guide the analysis of the PREVENT trial. This plan specifies the statistical methods for the evaluation of primary and secondary outcomes, and defines covariates for adjusted analyses a priori. Application of this statistical analysis plan to the PREVENT trial will facilitate unbiased analyses of clinical data. ClinicalTrials.gov , ID: NCT02040103 . Registered on 3 November 2013; Current controlled trials, ID: ISRCTN44653506 . Registered on 30 October 2013.

  20. Hereditary properties of Amenability modulo an ideal of Banach algebras

    Directory of Open Access Journals (Sweden)

    Hamidreza Rahimi

    2014-10-01

    Full Text Available In this paper we investigate some hereditary properties of amenability modulo an ideal of Banach algebras. We show thatif $(e_{\\alpha}_{\\alpha}$ is a bounded approximate identity modulo $I$ of a Banach algebra $A$ and $X$ is a neo-unital modulo $I$, then $(e_{\\alpha}_{\\alpha}$ is a bounded approximate identity for $X$. Moreover we show that amenability modulo an ideal of a Banach algebra $A$ can be only considered by the neo-unital modulo $I$ Banach algebra over $A$

  1. Radiation of ultrarelativistic particles passing through ideal and mosaic crystals

    International Nuclear Information System (INIS)

    Afanas'ev, A.M.

    1977-01-01

    When a charged particle passes through an ideal crystal, then besides the transition radiation, a new kind of radiation, connected with the periodic structure of the crystal is produced. The influence of mosaic structure of a crystal on the intensity of this radiation is considered. Simple analytical expressions for the integral intensity of this radiation for the case of an ideal crystal are obtained. The results show, that the integral radiation intensity depends weakly on the degree of crystal perfection

  2. [Multiple fractures of the lower extremities (a propos of 50 patients)].

    Science.gov (United States)

    Touzard, R C; Kudela, I

    1975-04-01

    According to a study of 50 multiple fractures of the lower limbs, the frequency of associated lesions justifies the creation of new multiple injury units, well equipped in which may be found specialists of all branches of surgery. Although internal fixation in one stage as an emergency, is ideal in all fractures, one should in fact be circumspect for the danger of infection should lead one to avoid carrying out internal fixation if this is not absolutely necessary.

  3. Provenance trials of larch in Siberia

    Energy Technology Data Exchange (ETDEWEB)

    Milyutin, L.I. [V.N. Sukachev Inst. of Forest SB RAS, Krasnoyarsk (Russian Federation)

    1995-12-31

    Some results of provenance trials of larch in Siberia are given. These provenance trials were established in the last thirty years by efforts of V.N. Sukaczev Inst. of Forest. Provenances and species of larch were tested in some field trials distributed over Siberia between Lat. N 52 deg and 66 deg, Long. E 88 deg and 113 deg: near Krasnoyarsk, in Republic Khakasia (an altitudes of 800 and 1200 metres), in the Lower Yenisei near Turukhansk, in the west and south regions of Krasnoyarsk territory, in the Upper Lena, near Chita. 2 refs

  4. Provenance trials of larch in Siberia

    Energy Technology Data Exchange (ETDEWEB)

    Milyutin, L I [V.N. Sukachev Inst. of Forest SB RAS, Krasnoyarsk (Russian Federation)

    1996-12-31

    Some results of provenance trials of larch in Siberia are given. These provenance trials were established in the last thirty years by efforts of V.N. Sukaczev Inst. of Forest. Provenances and species of larch were tested in some field trials distributed over Siberia between Lat. N 52 deg and 66 deg, Long. E 88 deg and 113 deg: near Krasnoyarsk, in Republic Khakasia (an altitudes of 800 and 1200 metres), in the Lower Yenisei near Turukhansk, in the west and south regions of Krasnoyarsk territory, in the Upper Lena, near Chita. 2 refs

  5. The Circuit Ideal of a Vector Configuration

    DEFF Research Database (Denmark)

    Jensen, Anders Nedergaard; Bogart, Tristram; Thomas, Rekha

    $, of $\\A$ which has numerous applications and is nontrivial to compute. Since circuits can be computed using linear algebra and the two ideals often coincide, it is worthwhile to understand when equality occurs. In this paper we study $\\ica$ in relation to $\\ia$ from various algebraic and combinatorial...

  6. How Is the Ideal Gas Law Explanatory?

    Science.gov (United States)

    Woody, Andrea I.

    2013-01-01

    Using the ideal gas law as a comparative example, this essay reviews contemporary research in philosophy of science concerning scientific explanation. It outlines the inferential, causal, unification, and erotetic conceptions of explanation and discusses an alternative project, the functional perspective. In each case, the aim is to highlight…

  7. Learning what feelings to desire: socialization of ideal affect through children's storybooks.

    Science.gov (United States)

    Tsai, Jeanne L; Louie, Jennifer Y; Chen, Eva E; Uchida, Yukiko

    2007-01-01

    Previous findings suggest that cultural factors influence ideal affect (i.e., the affective states that people ideally want to feel). Three studies tested the hypothesis that cultural differences in ideal affect emerge early in life and are acquired through exposure to storybooks. In Study 1, the authors established that consistent with previous findings, European American preschoolers preferred excited (vs. calm) states more (indexed by activity and smile preferences) and perceived excited (vs. calm) states as happier than Taiwanese Chinese preschoolers. In Study 2, it was observed that similar differences were reflected in the pictures (activities, expressions, and smiles) of best-selling storybooks in the United States and Taiwan. Study 3 found that across cultures, exposure to exciting (vs. calm) storybooks altered children's preferences for excited (vs. calm) activities and their perceptions of happiness. These findings suggest that cultural differences in ideal affect may be due partly to differential exposure to calm and exciting storybooks.

  8. Distribution of ideal cardiovascular health by educational levels from 1978 to 2006

    DEFF Research Database (Denmark)

    Olsen, Gitte S; Holm, Ann-Sofie S; Jørgensen, Torben

    2014-01-01

    BACKGROUND: The focus on improvements in ideal cardiovascular health is a relatively new approach and to our knowledge nobody has published the trend in regard to educational difference. DESIGN: Time trend analysis from six cross-sectional studies in 1978-2006 from the south-western part of the c......BACKGROUND: The focus on improvements in ideal cardiovascular health is a relatively new approach and to our knowledge nobody has published the trend in regard to educational difference. DESIGN: Time trend analysis from six cross-sectional studies in 1978-2006 from the south-western part...... index adjusted for age and stratified according to sex and educational level as length of vocational training. RESULTS: The proportion of women with ideal cardiovascular health increased from 2% in 1978 to 13......, the educational difference was less pronounced probably because very few men reached an ideal cardiovascular risk profile. This stresses the importance for preventive efforts targeting low educated groups, and men in particular....

  9. The effect of a sports chiropractic manual therapy intervention on the prevention of back pain, hamstring and lower limb injuries in semi-elite Australian Rules footballers: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Pollard Henry

    2010-04-01

    Full Text Available Abstract Background Hamstring injuries are the most common injury in Australian Rules football. It was the aims to investigate whether a sports chiropractic manual therapy intervention protocol provided in addition to the current best practice management could prevent the occurrence of and weeks missed due to hamstring and other lower-limb injuries at the semi-elite level of Australian football. Methods Sixty male subjects were assessed for eligibility with 59 meeting entry requirements and randomly allocated to an intervention (n = 29 or control group (n = 30, being matched for age and hamstring injury history. Twenty-eight intervention and 29 control group participants completed the trial. Both groups received the current best practice medical and sports science management, which acted as the control. Additionally, the intervention group received a sports chiropractic intervention. Treatment for the intervention group was individually determined and could involve manipulation/mobilization and/or soft tissue therapies to the spine and extremity. Minimum scheduling was: 1 treatment per week for 6 weeks, 1 treatment per fortnight for 3 months, 1 treatment per month for the remainder of the season (3 months. The main outcome measure was an injury surveillance with a missed match injury definition. Results After 24 matches there was no statistical significant difference between the groups for the incidence of hamstring injury (OR:0.116, 95% CI:0.013-1.019, p = 0.051 and primary non-contact knee injury (OR:0.116, 95% CI:0.013-1.019, p = 0.051. The difference for primary lower-limb muscle strains was significant (OR:0.097, 95%CI:0.011-0.839, p = 0.025. There was no significant difference for weeks missed due to hamstring injury (4 v14, χ2:1.12, p = 0.29 and lower-limb muscle strains (4 v 21, χ2:2.66, p = 0.10. A significant difference in weeks missed due to non-contact knee injury was noted (1 v 24, χ2:6.70, p = 0.01. Conclusions This study

  10. Solution of Riemann problem for ideal polytropic dusty gas

    International Nuclear Information System (INIS)

    Nath, Triloki; Gupta, R.K.; Singh, L.P.

    2017-01-01

    Highlights : • A direct approach is used to solve the Riemann problem for dusty ideal polytropic gas. • An analytical solution to the Riemann problem for dusty gas flow is obtained. • The existence and uniqueness of the solution in dusty gas is discussed. • Properties of elementary wave solutions of Riemann problem are discussed. • Effect of mass fraction of solid particles on the solution is presented. - Abstract: The Riemann problem for a quasilinear hyperbolic system of equations governing the one dimensional unsteady flow of an ideal polytropic gas with dust particles is solved analytically without any restriction on magnitude of the initial states. The elementary wave solutions of the Riemann problem, that is shock waves, rarefaction waves and contact discontinuities are derived explicitly and their properties are discussed, for a dusty gas. The existence and uniqueness of the solution for Riemann problem in dusty gas is discussed. Also the conditions leading to the existence of shock waves or simple waves for a 1-family and 3-family curves in the solution of the Riemann problem are discussed. It is observed that the presence of dust particles in an ideal polytropic gas leads to more complex expression as compared to the corresponding ideal case; however all the parallel results remain same. Also, the effect of variation of mass fraction of dust particles with fixed volume fraction (Z) and the ratio of specific heat of the solid particles and the specific heat of the gas at constant pressure on the variation of velocity and density across the shock wave, rarefaction wave and contact discontinuities are discussed.

  11. Public reason as a political ideal: John Rawls’s conception

    Directory of Open Access Journals (Sweden)

    Pavićević Đorđe

    2007-01-01

    Full Text Available The article dealt with Rawlsian idea of public reason as a convergence point of his conception of political liberalism. The idea of public reason is taken as a norm of political justification a as well as a political ideal. Major lines of criticism of the Rawls' conception are also discussed in the article. The conclusion is that is possible to defend major elements of Rawls' conception against criticism along Rawlsian lines of argumentation. The thesis advocated through the text is that it is significant legacy of Rawls' conception of public reason that it discloses limitations of political ideal of liberal democracy. It is argued that one important consequence is that liberalism has to disclaim its own moral superiority in order to make political ideal viable. The other is that any particular society has to find its moral bases in public reason of particular society, that is burdened with peculiar culture and history. .

  12. Ideal and conventional feedback systems for RWM suppression

    Energy Technology Data Exchange (ETDEWEB)

    Pustovitov, V.D.

    2002-01-01

    Feedback suppression of resistive wall modes (RWM) is studied analytically using a model based on a standard cylindrical approximation. Two feedback systems are compared: 'ideal', creating only the field necessary for RMW suppression, and 'conventional', like that used in the DIII-D tokamak and considered as a candidate for ITER. The widespread opinion that the feedback with poloidal sensors is better than that with radial sensors is discussed. It is shown that the 'conventional' feedback with radial sensors can be effective only in a limited range, while using the input signal from internal poloidal sensors allows easy fulfilment of the stability criterion. This is a property of the 'conventional' feedback, but the 'ideal' feedback would stabilise RWM in both cases. (author)

  13. Electronic Markets Ontology: ideal architecture for global capital market

    Directory of Open Access Journals (Sweden)

    Davide Khalil

    1998-11-01

    Full Text Available When approaching electronic capital market design and microstructure with the focus of analysing and improving existing markets with end-state analysis, it is necessary to name an ideal objective. This serves the purposes of technology evaluation and the development of a standard framework for structural measurement in modeling and language paradigm design. An ideal capital market architecture is presented in this paper that is feasible with current technology based on the end-to-end functionality of existing capital markets including internal requirements of participants. Various architectural and ethical issues are introduced and discussed sketching a framework for further work in quantifying electronic markets.

  14. Ideal 3D asymmetric concentrator

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Botella, Angel [Departamento Fisica Aplicada a los Recursos Naturales, Universidad Politecnica de Madrid, E.T.S.I. de Montes, Ciudad Universitaria s/n, 28040 Madrid (Spain); Fernandez-Balbuena, Antonio Alvarez; Vazquez, Daniel; Bernabeu, Eusebio [Departamento de Optica, Universidad Complutense de Madrid, Fac. CC. Fisicas, Ciudad Universitaria s/n, 28040 Madrid (Spain)

    2009-01-15

    Nonimaging optics is a field devoted to the design of optical components for applications such as solar concentration or illumination. In this field, many different techniques have been used for producing reflective and refractive optical devices, including reverse engineering techniques. In this paper we apply photometric field theory and elliptic ray bundles method to study 3D asymmetric - without rotational or translational symmetry - concentrators, which can be useful components for nontracking solar applications. We study the one-sheet hyperbolic concentrator and we demonstrate its behaviour as ideal 3D asymmetric concentrator. (author)

  15. Quantum cryptography with an ideal local relay

    DEFF Research Database (Denmark)

    Spedalieri, Gaetana; Ottaviani, Carlo; Braunstein, Samuel L.

    2015-01-01

    We consider two remote parties connected to a relay by two quantum channels. To generate a secret key, they transmit coherent states to the relay, where the states are subject to a continuous-variable (CV) Bell detection. We study the ideal case where Alice's channel is lossless, i.e., the relay ...

  16. Effectiveness of Acupressure on the Taichong Acupoint in Lowering Blood Pressure in Patients with Hypertension: A Randomized Clinical Trial

    Directory of Open Access Journals (Sweden)

    Gan-Hon Lin

    2016-01-01

    Full Text Available Objectives. To evaluate the effectiveness of acupressure on the Taichong acupoint in lowering systolic and diastolic blood pressure (BP in hypertensive patients. Methods. Eighty patients with hypertension attending a cardiology outpatient department in central Taiwan were included in this randomized clinical trial. Acupressure was applied to the Taichong acupoint in the experimental group (n=40 and to the first metatarsal (sham acupoint in the control group (n=40. Blood pressure was measured by electronic monitoring before and immediately 15 min and 30 min after acupressure. Results. The average age of the experimental and control participants was 59.3 ± 9.2 years and 62.7 ± 8.4 years, respectively. The two groups were similar for demographics and antihypertensive drug use. Mean systolic and diastolic BP in the experimental group decreased at 0, 15, and 30 min after acupressure (165.0/96.3, 150.4/92.7, 145.7/90.8, and 142.9/88.6 mmHg; no significant changes occurred in the control group. There was a significant difference in systolic and diastolic BP between the experimental and control groups immediately and 15 and 30 min after acupressure (p<0.05. Conclusion. Acupressure on the Taichong acupoint can lower BP in hypertensive patients and may be included in the nursing care plan for hypertension. However, additional studies are needed to determine the optimal dosage, frequency, and long-term effects of this therapy.

  17. Perturbative thermodynamic geometry of nonextensive ideal classical, Bose, and Fermi gases.

    Science.gov (United States)

    Mohammadzadeh, Hosein; Adli, Fereshteh; Nouri, Sahereh

    2016-12-01

    We investigate perturbative thermodynamic geometry of nonextensive ideal classical, Bose, and Fermi gases. We show that the intrinsic statistical interaction of nonextensive Bose (Fermi) gas is attractive (repulsive) similar to the extensive case but the value of thermodynamic curvature is changed by a nonextensive parameter. In contrary to the extensive ideal classical gas, the nonextensive one may be divided to two different regimes. According to the deviation parameter of the system to the nonextensive case, one can find a special value of fugacity, z^{*}, where the sign of thermodynamic curvature is changed. Therefore, we argue that the nonextensive parameter induces an attractive (repulsive) statistical interaction for zz^{*}) for an ideal classical gas. Also, according to the singular point of thermodynamic curvature, we consider the condensation of nonextensive Boson gas.

  18. Gender differences in the evaluation of physical attractiveness ideals for male and female body builds.

    Science.gov (United States)

    Salusso-Deonier, C J; Markee, N L; Pedersen, E L

    1993-06-01

    The purposes of this research were (1) to explore gender differences in the evaluation of physical attractiveness stimuli developed to represent commonly occurring real builds, (2) to identify observers' concepts of physical attractiveness ideals promoted by the media, and (3) to begin cross-validation of these stimuli as representations of observers' concepts of ideal physical attractiveness for male and female builds. Responses included (1) open-ended descriptions of ideal male and ideal female build, (2) ratings of relative attractiveness of 12 male and 15 female stimuli, (3) selections of stimulus types which best represented ideal builds, and (4) selections of stimulus types perceived to be promoted by the media. Analysis showed strong cross-validation among modes of response. Ideal male build included average/balanced type (small and medium), lean/broad-shouldered type (large), and muscular bulk type (medium). Ideal female body build included average/balanced type (small and medium) and lean/broad-shouldered type (small and medium). Gender differences were in emphasis only. Women emphasized lean/broad-shouldered and average/balanced male types. Men emphasized the muscular bulk male type. Body types perceived to be media-promoted highlighted stereotypic male muscularity and female leanness.

  19. Bell inequalities under non-ideal conditions

    OpenAIRE

    Especial, João N. C.

    2012-01-01

    Bell inequalities applicable to non-ideal EPRB experiments are critical to the interpretation of experimental Bell tests. In this article it is shown that previous treatments of this subject are incorrect due to an implicit assumption and new inequalities are derived under general conditions. Published experimental evidence is reinterpreted under these results and found to be entirely compatible with local-realism, both, when experiments involve inefficient detection, if fair-sampling detecti...

  20. Narrowing beam-walking is a clinically feasible approach for assessing balance ability in lower-limb prosthesis users

    Directory of Open Access Journals (Sweden)

    Andrew Sawers

    2018-03-01

    Full Text Available Objective: Challenging clinical balance tests are needed to expose balance deficits in lower-limb prost-hesis users. This study examined whether narrowing beam-walking could overcome conceptual and practical limitations identified in fixed-width beam-walking. Design: Cross-sectional. Participants: Unilateral lower-limb prosthesis users. Methods: Participants walked 10 times along a low, narrowing beam. Performance was quantified using the normalized distance walked. Heuristic rules were applied to determine whether the narrowing beam task was “too easy,” “too hard,” or “appropriately challenging” for each participant. Linear regression and Bland-Altman plots were used to determine whether combinations of the first 5 trials could predict participants’ stable beam-walking performance. Results: Forty unilateral lower-limb prosthesis users participated. Narrowing beam-walking was appropriately challenging for 98% of participants. Performance stabilized for 93% of participants within 5 trials, while 62% were stable across all trials. The mean of trials 3–5 accurately predicted stable performance. Conclusion: A clinical narrowing beam-walking test is likely to challenge a range of lower-limb prosthesis users, have minimal administrative burden, and exhibit no floor or ceiling effects. Narrowing beam-walking is therefore a clinically viable method to evaluate lower-limb prosthesis users’ balance ability, but requires psychometric testing before it is used to assess fall risk.

  1. Effect of pairwise additivity on finite-temperature behavior of classical ideal gas

    Science.gov (United States)

    Shekaari, Ashkan; Jafari, Mahmoud

    2018-05-01

    Finite-temperature molecular dynamics simulations have been applied to inquire into the effect of pairwise additivity on the behavior of classical ideal gas within the temperature range of T = 250-4000 K via applying a variety of pair potentials and then examining the temperature dependence of a number of thermodynamical properties. Examining the compressibility factor reveals the most deviation from ideal-gas behavior for the Lennard-Jones system mainly due to the presence of both the attractive and repulsive terms. The systems with either attractive or repulsive intermolecular potentials are found to present no resemblance to real gases, but the most similarity to the ideal one as temperature rises.

  2. Ground-state pressure of an ideal Fermi gas

    International Nuclear Information System (INIS)

    Delsante, A.E.; Frankel, N.E.

    1979-01-01

    A simple relationship between the pressure, internal energy and Fermi energy of an ideal ultra-degenerate Fermi gas is derived in two ways. The conditions for its validity and its use in simplifying calculations are discussed

  3. Effect of race/ethnicity on participation in HIV vaccine trials and comparison to other trials of biomedical prevention.

    Science.gov (United States)

    Dhalla, Shayesta; Poole, Gary

    2014-01-01

    Racial/ethnic minorities are underrepresented in actual HIV vaccine trials in North America, and willingness to participate (WTP) and retention in an HIV vaccine trial may differ from that in Whites. In this review, the authors identified HIV vaccine preparedness studies (VPS) in North America in high-risk populations that examined the relationship between race/ethnicity and WTP in a preventive phase 3 HIV vaccine trial, and the relationship to retention. Studies were categorized by risk group, and comparison group (Whites vs. non-Whites). Other types of trials of biomedical prevention were also identified, and WTP and retention rates were compared and contrasted to actual HIV vaccine trials. In the studies identified, WTP in a hypothetical trial HIV vaccine trial did not differ by race/ethnicity. In contrast, actual HIV vaccine trials, an HIV acquisition trial, and a phase 2B preexposure prophylaxis (PrEP) trial have enrolled a large percentage of White men. Human papilloma virus (HPV) privately-funded trials have also enrolled a large number of Whites, due to convenience sampling. Retention in the HIV acquisition trial was lower in African-Americans compared with Whites. Strategies to increase WTP and enhanced retention (ER) strategies may help in recruiting and retaining minority participants in actual HIV vaccine trials and other trials of biomedical prevention.

  4. Ideal cardiovascular health and psychosocial risk factors among Finnish female municipal workers.

    Science.gov (United States)

    Veromaa, Veera; Kautiainen, Hannu; Saxen, Ulla; Malmberg-Ceder, Kirsi; Bergman, Elina; Korhonen, Päivi E

    2017-02-01

    Ideal cardiovascular health has been defined by the American Heart Association as the absence of disease and the presence of seven key health factors and behaviours. However, little is known about the mental aspects associated with ideal cardiovascular health metrics. The objective of this study was to assess the relationships between psychosocial risk factors and ideal cardiovascular health metrics among Finnish women at municipal work units. A cross-sectional study was conducted in Finland among 732 female employees (mean±SD age 48±10 years) from ten work units in 2014. Ideal cardiovascular health metrics were evaluated with a physical examination, laboratory tests, medical history and self-administrated questionnaires. Psychosocial risk factors (social isolation, stress, depressive symptoms, anxiety, hostility and type D personality) were assessed with core questions as suggested by the European Society of Cardiology. The prevalence of having 5-7 ideal cardiovascular health metrics was 183 (25.0%), of whom 54.1% had at least one psychosocial risk factor. Anxiety (31.3%), work stress (30.7%) and type D personality (26.1%) were the most prevalent of the psychosocial risk factors. The prevalence of depressive symptoms ( ppsychosocial risk factors at municipal work units. Although the association is possibly bidirectional, screening and treating depression and dealing with type D personality might be crucial in improving cardiovascular health among women.

  5. The Decisions of Elementary School Principals: A Test of Ideal Type Methodology.

    Science.gov (United States)

    Greer, John T.

    Interviews with 25 Georgia elementary school principals provided data that could be used to test an application of Max Weber's ideal type methodology to decision-making. Alfred Schuetz's model of the rational act, based on one of Weber's ideal types, was analyzed and translated into describable acts and behaviors. Interview procedures were…

  6. Turkish Primary Science Teachers' Perceptions of an Ideal Teacher Education System

    Science.gov (United States)

    Korkmaz, Hunkar; Altindag, Ahmet

    2017-01-01

    The goals of this descriptive study were to determine Turkish pre-service science teachers' perceptions of an ideal teacher education system. The sample consisted of 137 pre-service teachers, including 74 females and 63 males. The questionnaire was based on open-ended questions and was developed to investigate ideal teacher education system…

  7. Keeping the Bar Low: Why Russia's Nonresident Fathers Accept Narrow Fatherhood Ideals

    Science.gov (United States)

    Utrata, Jennifer

    2008-01-01

    Although most Russian nonresident fathers feel torn between old and new ideals of fatherhood, they end up accepting older, narrow ideals. Fathers reproduce the dominant gender discourse, which deems men irresponsible and infantile and diminishes the importance of fathers. On the basis of extensive fieldwork, including in-depth interviews (N = 21)…

  8. Hall effect in non-ideal plasma of argon and xenon

    International Nuclear Information System (INIS)

    Shilkin, N.S.; Dudin, S.V.; Gryaznov, V.K.; Mintsev, V.B.; Fortov, V.E.

    2003-01-01

    The first data on the measurement of the electron concentration (10 16 -10 20 cm -3 ) of the low-temperature (0.5-1 eV) non-ideal (0.01 -6 -10 -1 ) inert gases plasma are presented. The measurements of the Hall constant and electric conductivity in the non-ideal partially ionized plasma of argon and xenon are carried out through the sounding methods. The plasma generation was accomplished behind the shock waves front through the linear explosive generators. The obtained results are compared with a number of the plasma models [ru

  9. Quantifying ataxia: ideal trajectory analysis--a technical note

    Science.gov (United States)

    McPartland, M. D.; Krebs, D. E.; Wall, C. 3rd

    2000-01-01

    We describe a quantitative method to assess repeated stair stepping stability. In both the mediolateral (ML) and anterioposterior (AP) directions, the trajectory of the subject's center of mass (COM) was compared to an ideal sinusoid. The two identified sinusoids were unique in each direction but coupled. Two dimensionless numbers-the mediolateral instability index (IML) and AP instability index (IAP)-were calculated using the COM trajectory and ideal sinusoids for each subject with larger index values resulting from less stable performance. The COM trajectories of nine nonimpaired controls and six patients diagnosed with unilateral or bilateral vestibular labyrinth hypofunction were analyzed. The average IML and IAP values of labyrinth disorder patients were respectively 127% and 119% greater than those of controls (panalysis distinguishes persons with labyrinth disorder from those without. The COM trajectories also identify movement inefficiencies attributable to vestibulopathy.

  10. Transcendental idealism and structuralism

    Directory of Open Access Journals (Sweden)

    Ivan Vuković

    2016-02-01

    Full Text Available The author examines possible analogies between Kant’s transcendental idealism and de Saussure’s and Levi-Strauss’s structuralism, in order to analyse if the former can be understood as a predecessor for the later. The author shows that both teachings assume a priori formal framework, but they diverge in the ways they describe it, as well as in understanding of its function. Consequently, the author concludes that structuralism can be seen as one possible use of Kant’s idea about the existence of such a frame. Furthermore, the author claims that Ricker’s understanding of structuralism as ‘Kantianism without transcendental subject’ should be rejected, since a teaching which does not assume existence of such subject cannot be understood as Kantian.

  11. High resolution kinetic beam schemes in generalized coordinates for ideal quantum gas dynamics

    International Nuclear Information System (INIS)

    Shi, Yu-Hsin; Huang, J.C.; Yang, J.Y.

    2007-01-01

    A class of high resolution kinetic beam schemes in multiple space dimensions in general coordinates system for the ideal quantum gas is presented for the computation of quantum gas dynamical flows. The kinetic Boltzmann equation approach is adopted and the local equilibrium quantum statistics distribution is assumed. High-order accurate methods using essentially non-oscillatory interpolation concept are constructed. Computations of shock wave diffraction by a circular cylinder in an ideal quantum gas are conducted to illustrate the present method. The present method provides a viable means to explore various practical ideal quantum gas flows

  12. A moral house divided: How idealized family models impact political cognition.

    Science.gov (United States)

    Feinberg, Matthew; Wehling, Elisabeth

    2018-01-01

    People's political attitudes tend to fall into two groups: progressive and conservative. Moral Politics Theory asserts that this ideological divide is the product of two contrasting moral worldviews, which are conceptually anchored in individuals' cognitive models about ideal parenting and family life. These models, here labeled the strict and nurturant models, serve as conceptual templates for how society should function, and dictate whether one will endorse more conservative or progressive positions. According to Moral Politics Theory, individuals map their parenting ideals onto the societal domain by engaging the nation-as-family metaphor, which facilitates reasoning about the abstract social world (the nation) in terms of more concrete world experience (family life). In the present research, we conduct an empirical examination of these core assertions of Moral Politics Theory. In Studies 1-3, we experimentally test whether family ideals directly map onto political attitudes while ruling out alternative explanations. In Studies 4-5, we use both correlational and experimental methods to examine the nation-as-family metaphor's role in facilitating the translation of family beliefs into societal beliefs and, ultimately, political attitudes. Overall, we found consistent support for Moral Politics Theory's assertions that family ideals directly impact political judgment, and that the nation-as-family metaphor serves a mediating role in this phenomenon.

  13. Near-ideal lasing with a uniform wiggler

    Energy Technology Data Exchange (ETDEWEB)

    Warren, R.W.; Sollid, J.E.; Feldman, D.W.; Stein, W.E.; Johnson, W.J.; Lumpkin, A.H.; Goldstein, J.C.

    1988-01-01

    Over the years the Los Alamos FEL team has reduced or eliminated many of the experimental problems that resulted in non-ideal lasing. The major problems were accelerator instabilities that cause noise and fluctuations in current, energy, and timing; wakefield effects in the wiggler and beamline that introduce fluctuations in the beam's energy; and mirror nonlinearities caused by free carriers produced in the mirror by the high light levels, which caused extra light losses and interfered with the diagnostics. Lasing is not thought to be ideal in that it lacks major disturbing effects and is limited only by emittance, energy spread, and peak current. In this paper we describe the features of lasing that we have observed over a range of optical power of 1000, from the onset of lasing, to the threshold of the sideband instability, to the organization of regular optical spikes, to the region of chaotic spikes. Cavity-length detuning is presented as an ideal technique, in most circumstances, to completely suppress sidebands. With detuning one can easily switch operating modes from that giving the highest efficiency (chaotic spiking) to that giving the narrowest spectral line (no sidebands). Alternative techniques for sideband suppression normally use some kind of wavelength selective device (e.g., a grating) inserted in the cavity. With detuning, there is no need for such a device, and, therefore, no conflict between the wavelength control exerted by this extra optical component and that exerted by the energy of the electron beam. Lasing, therefore, starts easily, a shift in wavelength, i.e., chirp, is easily accomplished, and the consequences of inadequate control of the electron beam energy are not severe. 35 refs., 16 figs.

  14. Statistical Theory of the Ideal MHD Geodynamo

    Science.gov (United States)

    Shebalin, J. V.

    2012-01-01

    A statistical theory of geodynamo action is developed, using a mathematical model of the geodynamo as a rotating outer core containing an ideal (i.e., no dissipation), incompressible, turbulent, convecting magnetofluid. On the concentric inner and outer spherical bounding surfaces the normal components of the velocity, magnetic field, vorticity and electric current are zero, as is the temperature fluctuation. This allows the use of a set of Galerkin expansion functions that are common to both velocity and magnetic field, as well as vorticity, current and the temperature fluctuation. The resulting dynamical system, based on the Boussinesq form of the magnetohydrodynamic (MHD) equations, represents MHD turbulence in a spherical domain. These basic equations (minus the temperature equation) and boundary conditions have been used previously in numerical simulations of forced, decaying MHD turbulence inside a sphere [1,2]. Here, the ideal case is studied through statistical analysis and leads to a prediction that an ideal coherent structure will be found in the form of a large-scale quasistationary magnetic field that results from broken ergodicity, an effect that has been previously studied both analytically and numerically for homogeneous MHD turbulence [3,4]. The axial dipole component becomes prominent when there is a relatively large magnetic helicity (proportional to the global correlation of magnetic vector potential and magnetic field) and a stationary, nonzero cross helicity (proportional to the global correlation of velocity and magnetic field). The expected angle of the dipole moment vector with respect to the rotation axis is found to decrease to a minimum as the average cross helicity increases for a fixed value of magnetic helicity and then to increase again when average cross helicity approaches its maximum possible value. Only a relatively small value of cross helicity is needed to produce a dipole moment vector that is aligned at approx.10deg with the

  15. Edge localized linear ideal magnetohydrodynamic instability studies in an extended-magnetohydrodynamic code

    International Nuclear Information System (INIS)

    Burke, B. J.; Kruger, S. E.; Hegna, C. C.; Zhu, P.; Snyder, P. B.; Sovinec, C. R.; Howell, E. C.

    2010-01-01

    A linear benchmark between the linear ideal MHD stability codes ELITE [H. R. Wilson et al., Phys. Plasmas 9, 1277 (2002)], GATO [L. Bernard et al., Comput. Phys. Commun. 24, 377 (1981)], and the extended nonlinear magnetohydrodynamic (MHD) code, NIMROD [C. R. Sovinec et al.., J. Comput. Phys. 195, 355 (2004)] is undertaken for edge-localized (MHD) instabilities. Two ballooning-unstable, shifted-circle tokamak equilibria are compared where the stability characteristics are varied by changing the equilibrium plasma profiles. The equilibria model an H-mode plasma with a pedestal pressure profile and parallel edge currents. For both equilibria, NIMROD accurately reproduces the transition to instability (the marginally unstable mode), as well as the ideal growth spectrum for a large range of toroidal modes (n=1-20). The results use the compressible MHD model and depend on a precise representation of 'ideal-like' and 'vacuumlike' or 'halo' regions within the code. The halo region is modeled by the introduction of a Lundquist-value profile that transitions from a large to a small value at a flux surface location outside of the pedestal region. To model an ideal-like MHD response in the core and a vacuumlike response outside the transition, separate criteria on the plasma and halo Lundquist values are required. For the benchmarked equilibria the critical Lundquist values are 10 8 and 10 3 for the ideal-like and halo regions, respectively. Notably, this gives a ratio on the order of 10 5 , which is much larger than experimentally measured values using T e values associated with the top of the pedestal and separatrix. Excellent agreement with ELITE and GATO calculations are made when sharp boundary transitions in the resistivity are used and a small amount of physical dissipation is added for conditions very near and below marginal ideal stability.

  16. An innovative method for ideal and resistive MHD stability analysis of tokamaks

    International Nuclear Information System (INIS)

    Tokuda, S.

    2001-01-01

    An advanced asymptotic matching method of ideal and resistive MHD stability analysis in tokamak is reported. The report explains a solution method of two-dimensional Newcomb equation, dispersion relation for an unstable ideal MHD mode in tokamak, and a new scheme for solving resistive MHD inner layer equations as an initial-value problem. (author)

  17. An innovative method for ideal and resistive MHD stability analysis of tokamaks

    International Nuclear Information System (INIS)

    Tokuda, S.

    2001-01-01

    An advanced asymptotic matching method of ideal and resistive MHD stability analysis in tokamaks is reported. A solution method for the two dimensional Newcomb equation, a dispersion relation for an unstable ideal MHD mode in tokamaks and a new scheme for solving resistive MHD inner layer equations as an initial value problem are reported. (author)

  18. On the Relations between Parents' Ideals and Children's Autonomy

    Science.gov (United States)

    de Ruyter, Doret J.; Schinkel, Anders

    2013-01-01

    In this article Doret J. de Ruyter and Anders Schinkel argue that parents' ideals can enhance children's autonomy, but that they may also have a detrimental effect on the development of children's autonomy. After describing the concept of "ideals" and elucidating a systems theoretical conception of autonomy, de Ruyter and…

  19. Performance evaluation of contrast-detail in full field digital mammography systems using ideal (Hotelling) observer vs. conventional automated analysis of CDMAM images for quality control of contrast-detail characteristics.

    Science.gov (United States)

    Delakis, Ioannis; Wise, Robert; Morris, Lauren; Kulama, Eugenia

    2015-11-01

    The purpose of this work was to evaluate the contrast-detail performance of full field digital mammography (FFDM) systems using ideal (Hotelling) observer Signal-to-Noise Ratio (SNR) methodology and ascertain whether it can be considered an alternative to the conventional, automated analysis of CDMAM phantom images. Five FFDM units currently used in the national breast screening programme were evaluated, which differed with respect to age, detector, Automatic Exposure Control (AEC) and target/filter combination. Contrast-detail performance was analysed using CDMAM and ideal observer SNR methodology. The ideal observer SNR was calculated for input signal originating from gold discs of varying thicknesses and diameters, and then used to estimate the threshold gold thickness for each diameter as per CDMAM analysis. The variability of both methods and the dependence of CDMAM analysis on phantom manufacturing discrepancies also investigated. Results from both CDMAM and ideal observer methodologies were informative differentiators of FFDM systems' contrast-detail performance, displaying comparable patterns with respect to the FFDM systems' type and age. CDMAM results suggested higher threshold gold thickness values compared with the ideal observer methodology, especially for small-diameter details, which can be attributed to the behaviour of the CDMAM phantom used in this study. In addition, ideal observer methodology results showed lower variability than CDMAM results. The Ideal observer SNR methodology can provide a useful metric of the FFDM systems' contrast detail characteristics and could be considered a surrogate for conventional, automated analysis of CDMAM images. Copyright © 2015 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  20. A simple ideal magnetohydrodynamical model of vertical disruption events in tokamaks

    International Nuclear Information System (INIS)

    Fitzpatrick, R.

    2009-01-01

    A simple model of axisymmetric vertical disruption events (VDEs) in tokamaks is presented in which the halo current force exerted on the vacuum vessel is calculated directly from linear, marginally stable, ideal-magnetohydrodynamical (MHD) stability analysis. The basic premise of the model is that the halo current force modifies pressure balance at the edge of the plasma, and therefore also modifies ideal-MHD plasma stability. In order to prevent the ideal vertical instability, responsible for the VDE, from growing on the very short Alfven time scale, the halo current force must adjust itself such that the instability is rendered marginally stable. The model predicts halo currents which are similar in magnitude to those observed experimentally. An approximate nonaxisymmetric version of the model is developed in order to calculate the toroidal peaking factor for the halo current force.

  1. Tv nyheder: Journalistiske Idealer er under Pres

    DEFF Research Database (Denmark)

    Thomsen, Line Hassall

    2013-01-01

    som tv-journalisterne ville ønske det. Tv-journalister har mange store idealer om god journalistik og public service. Men de vilkår journalisterne arbejder under gør idealerne nærmest umulige at opnå i dagligdagen. I dag er det ikke de journalistiske idealer men markedskræfterne der driver de...... Journalist” inside Public Service TV Newsrooms in the UK and Denmark’. Under ph.d.- studiet har jeg tilbragt halvandet år med deltager-observation på de fire største tv-redaktioner i England og Danmark. Jeg har observeret og deltaget i det daglige arbejde på redaktionerne hos TV Avisen og TV2 Nyhederne og i...... licensfinansieret tv-station. Men der tog jeg fejl. Jeg ledte efter forskelligheder, men fandt ligheder. Efterhånden som feltstudiet tog fat gik det op for mig at journalisterne på de fire forskellige tv-stationer arbejdede og tænkte ens. Derudover gik det op for mig at mange af journalisterne på de forskelligt...

  2. Randomised controlled trial of the cost-effectiveness of water-based therapy for lower limb osteoarthritis.

    Science.gov (United States)

    Cochrane, T; Davey, R C; Matthes Edwards, S M

    2005-08-01

    To determine the efficacy of community water-based therapy for the management of lower limb osteoarthritis (OA) in older patients. A pre-experimental matched-control study was used to estimate efficacy of water-based exercise treatment, to check design assumptions and delivery processes. The main study was a randomised controlled trial of the effectiveness of water-based exercise (treatment) compared with usual care (control) in older patients with hip and/or knee OA. The latter was accompanied by an economic evaluation comparing societal costs and consequences of the two treatments. Water exercise was delivered in public swimming pools in the UK. Physical function assessments were carried out in established laboratory settings. 106 patients (93 women, 13 men) over the age of 60 years with confirmed hip and/or knee OA took part in the preliminary study. A similar, but larger, group of 312 patients (196 women, 116 men) took part in the main study, randomised into control (159) and water exercise (153) groups. Control group patients received usual care with quarterly semi-structured telephone interview follow-up only. The intervention in the main study lasted for 1 year, with a further follow-up period of 6 months. Pain score on the Western Ontario and McMaster Universities OA index (WOMAC). Additional outcome measures were included to evaluate effects on quality of life, cost-effectiveness and physical function measurements. Short-term efficacy of water exercise in the management of lower limb OA was confirmed, with effect sizes ranging from 0.44 [95% confidence interval (CI) 0.03 to 0.85] on WOMAC pain to 0.76 (95% CI 0.33 to 1.17) on WOMAC physical function. Of 153 patients randomised to treatment, 82 (53.5%) were estimated to have complied satisfactorily with their treatment at the 1-year point. This had declined to 28 (18%) by the end of the 6-month follow-up period, during which support for the intervention had been removed and those wishing to continue

  3. Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial-PROSPECT: protocol for a feasibility randomized pilot trial.

    Science.gov (United States)

    Johnstone, Jennie; Meade, Maureen; Marshall, John; Heyland, Daren K; Surette, Michael G; Bowdish, Dawn Me; Lauzier, Francois; Thebane, Lehana; Cook, Deborah J

    2015-01-01

    Probiotics are defined as live microorganisms that may confer health benefits when ingested. Meta-analysis of probiotic trials suggests a 25 % lower ventilator-associated pneumonia (VAP) and 18 % lower infection rates overall when administered to patients in the intensive care unit (ICU). However, prior trials are small, largely single center, and at high risk of bias. Before a large rigorous trial is launched, testing whether probiotics confer benefit, harm, or have no impact, a pilot trial is needed. The aim of the PROSPECT Pilot Trial is to determine the feasibility of performing a larger trial in mechanically ventilated critically ill patients investigating Lactobacillus rhamnosus GG. A priori, we determined that the feasibility of the larger trial would be based on timely recruitment, high protocol adherence, minimal contamination, and an acceptable VAP rate. Patients ≥18 years old in the ICU who are anticipated to receive mechanical ventilation for ≥72 hours will be included. Patients are excluded if they are at increased risk of probiotic-associated infection, have strict enteral medication contraindications, are pregnant, previously enrolled in a related trial, or are receiving palliative care. Following informed consent, patients are randomized in variable unspecified block sizes in a fixed 1:1 ratio, stratified by ICU, and medical, surgical, or trauma admitting diagnosis. Patients receive 1 × 10 10 colony forming units of L. rhamnosus GG (Culturelle, Locin Industries Ltd) or an identical placebo suspended in tap water administered twice daily via nasogastric tube in the ICU. Clinical and research staff, patients, and families are blinded. The primary outcomes for this pilot trial are the following: (1) recruitment success, (2) ≥90 % protocol adherence, (3) ≤5 % contamination, and (4) ~10 % VAP rate. Additional clinical outcomes are VAP, other infections, diarrhea (total, antibiotic associated, and Clostridium difficile), ICU and

  4. REALISM, IDEALISM AND CRISIS RESOLUTION IN NIGERIA: A ...

    African Journals Online (AJOL)

    user

    2016-06-02

    Jun 2, 2016 ... Introduction ..... stipulated by all, there must be someone or a group who must interpret them; and such a person or group must be empowered to do so. ..... theory, idealism resolves conflicts leaving the parties involved with a ...

  5. Thin-plate spline analysis of arch form in a Southern European population with an ideal natural occlusion.

    Science.gov (United States)

    Camporesi, Matteo; Franchi, Lorenzo; Baccetti, Tiziano; Antonini, Antonino

    2006-04-01

    The purpose of the present study was to identify the mean configuration of the clinical arch form in a sample of Southern European subjects with ideal natural occlusion by means of Procrustes analysis, and to compare the identified configuration with 10 commercially produced arch forms by means of thin-plate spline (TPS) analysis. The sample comprised the study casts of 50 subjects (26 males and 24 females). The mean age of the sample was 26 years +/- 4 years. All subjects were young Caucasian adults of Southern European ancestry, and presented with an ideal natural occlusion. The three-dimensional (3D) co-ordinates of all dental points (facial axis points) were digitized using a 3D electromagnetic digitizer. The morphometric technique of TPS analysis with permutation tests was used to compare the configurations of landmarks in the various specimens. No sexual dimorphism was found for either upper or lower arch forms when the shape of the arches was assessed independently from size. The commercially available arch form that showed the least, though statistically significant, shape difference with respect to the average calculated configuration was the Brader arch form.

  6. On the Ideal Convergence of Double Sequences in Locally Solid Riesz Spaces

    Directory of Open Access Journals (Sweden)

    A. Alotaibi

    2014-01-01

    Full Text Available The aim of this paper is to define the notions of ideal convergence, I-bounded for double sequences in setting of locally solid Riesz spaces and study some results related to these notions. We also define the notion of I*-convergence for double sequences in locally solid Riesz spaces and establish its relationship with ideal convergence.

  7. Getting the Distance Right: Ideal and Nonideal Theory in Philosophy of Education

    Science.gov (United States)

    Shuffelton, Amy B.

    2015-01-01

    When the debate over the value of ideal and nonideal theory crosses from political philosophy into philosophy of education, do the implications of the debate shift, and, if so, how? In this piece, Amy Shuffelton considers the premise that no normative political theory, ideal or nonideal, is of any use to human beings unless it can be affiliated…

  8. Duct-to-mucosa versus dunking techniques of pancreaticojejunostomy after pancreaticoduodenectomy: Do we need more trials? A systematic review and meta-analysis with trial sequential analysis.

    Science.gov (United States)

    Kilambi, Ragini; Singh, Anand Narayan

    2018-03-25

    Pancreaticojejunostomy (PJ is the most widely used reconstruction technique after pancreaticoduodenectomy. Despite several randomized trials, the ideal technique of pancreaticojejunostomy remains debatable. We planned a meta-analysis of randomized trials comparing the two most common techniques of PJ (duct-to-mucosa and dunking) to identify the best available evidence in the current literature. We searched the Pubmed/Medline, Web of science, Science citation index, Google scholar and Cochrane Central Register of Controlled Trials electronic databases till October 2017 for all English language randomized trials comparing the two approaches. Statistical analysis was performed using Review Manager (RevMan), Version 5.3. Copenhagen: The Nordic Cochrane Center, The Cochrane Collaboration, 2014 and results were expressed as odds ratio for dichotomous and mean difference for continuous variables. P-value ≤ 0.05 was considered significant. Trial sequential analysis was performed using TSA version 0.9.5.5 (Copenhagen: The Copenhagen Trial Unit, Center for Clinical Intervention Research, 2016). A total of 8 trials were included, with a total of 1043 patients (DTM: 518; Dunking: 525). There was no significant difference between the two groups in terms of overall as well as clinically relevant POPF rate. Similarly, both groups were comparable for the secondary outcomes. Trial sequential analysis revealed that the required information size had been crossed without achieving a clinically significant difference for overall POPF; and though the required information size had not been achieved for CR-POPF, the current data has already crossed the futility line for CR-POPF with a 10% risk difference, 80% power and 5% α error. This meta-analysis found no significant difference between the two techniques in terms of overall and CR-POPF rates. Further, the existing evidence is sufficient to conclude lack of difference and further trials are unlikely to result in any change in the

  9. Ideal Gas Resonance Scattering Kernel Routine for the NJOY Code

    International Nuclear Information System (INIS)

    Rothenstein, W.

    1999-01-01

    In a recent publication an expression for the temperature-dependent double-differential ideal gas scattering kernel is derived for the case of scattering cross sections that are energy dependent. Some tabulations and graphical representations of the characteristics of these kernels are presented in Ref. 2. They demonstrate the increased probability that neutron scattering by a heavy nuclide near one of its pronounced resonances will bring the neutron energy nearer to the resonance peak. This enhances upscattering, when a neutron with energy just below that of the resonance peak collides with such a nuclide. A routine for using the new kernel has now been introduced into the NJOY code. Here, its principal features are described, followed by comparisons between scattering data obtained by the new kernel, and the standard ideal gas kernel, when such comparisons are meaningful (i.e., for constant values of the scattering cross section a 0 K). The new ideal gas kernel for variable σ s 0 (E) at 0 K leads to the correct Doppler-broadened σ s T (E) at temperature T

  10. The ideal gases of tachyons

    International Nuclear Information System (INIS)

    Mrowczynski, St.

    1984-01-01

    The formalism of statistical mechanics of particles slower than light has been considered from the point of view of the application of this formalism for the description of tachyons. Properties of ideal gases of tachyons have been discussed in detail. After finding general formulae for quantum, Bose and Fermi gases the classical limit has been considered. It has been shown that Bose-Einstein condensation occurs. The tachyon gas of bosons violates the third principle of thermodynamics. Degenerated Fermi gas has been considered and in this case the entropy vanishes at zero temperature. Difficulties of formulating covariant statistical mechanics have been discussed

  11. Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis

    DEFF Research Database (Denmark)

    Rossebo, A.B.; Pedersen, T.R.; Boman, K.

    2008-01-01

    BACKGROUND: Hyperlipidemia has been suggested as a risk factor for stenosis of the aortic valve, but lipid-lowering studies have had conflicting results. METHODS: We conducted a randomized, double-blind trial involving 1873 patients with mild-to-moderate, asymptomatic aortic stenosis. The patients...

  12. Tel Aviv. Tracing the Ideal City dream

    Directory of Open Access Journals (Sweden)

    Leonova, Yulia

    2017-04-01

    Full Text Available In descriptions of Tel Aviv often occur reflections about the ideal “first Hebrew city”. A gap between real Tel Aviv and its visionary model is a commonplace. Nevertheless, links between them are plentiful, although they are discussed either with irony or with pathos. The paper gives a cursory review of some of such links.

  13. Thought-shape fusion in young healthy females appears after vivid imagination of thin ideals.

    Science.gov (United States)

    Wyssen, Andrea; Coelho, Jennifer S; Wilhelm, Peter; Zimmermann, Grégoire; Munsch, Simone

    2016-09-01

    It has been shown that exposure to female thin ideals in media has minimal to moderate direct effects on body image satisfaction (BIS), mood and dysfunctional eating in healthy young women. Evidence has been found for several intervening variables such as social comparison processes. Accordingly it is assumed, that cognitive processing (rather than mere media exposure) is crucial. Consequently, vivid imagination of thin ideals after exposure to a fashion magazine was induced in order to trigger cognitive processes. Changes in mood, BIS and resulting bodyrelated cognitive distortions (Thought-Shape Fusion Body, TSF-B) were assessed. A total of 91 healthy women (mean age 21.9 years, SD = 2.0) were exposed to either a fashion magazine (thin-ideal group) or a nature magazine (control group) in a waiting room design. Afterwards they were instructed to vividly imagine either the thin ideals or landscapes. When exposed to thin ideals, a significant decrease in mood and BIS emerged after vivid imagination, but not after mere magazine exposure. Imagining thin ideals triggered body-related cognitive distortions (TSF-B). A higher degree of eating disorder (ED) symptomatology amplified this effect. These findings apply to young healthy females and cannot be generalized to samples with obesity, EDs or males. Internal validity is limited since the intensity of the exposure has not been systematically controlled. Vivid imagination of thin ideals promoted by magazines results in impaired mood and BIS and moreover in body-related cognitive distortions (TSF-B) in healthy women, especially, for those with stronger ED symptomatology. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Single exposure to disclaimers on airbrushed thin ideal images increases negative thought accessibility.

    Science.gov (United States)

    Selimbegović, Leila; Chatard, Armand

    2015-01-01

    Disclaimers on airbrushed thin ideal images can attract attention to the thin ideal standard promoted by the advertisements, which can be damaging rather than helpful. In this study, 48 female college students were exposed to a thin ideal image including a disclaimer, a neutral sentence, or nothing. Two weeks and two months after this, they were again exposed to the same image but with no accompanying text in any of the conditions. Negative thought accessibility was assessed three times, after each exposure to the thin-ideal image, using reaction time measures. Participants randomly assigned to the disclaimer condition systematically showed greater accessibility of negative thoughts than those in the other two conditions, irrespective of the time of measurement. These results suggest that disclaimers on airbrushed images may have some counter-productive effects by accentuating the problems that they precisely aim to address. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Thinspiration: Self-Improvement Versus Self-Evaluation Social Comparisons with Thin-Ideal Media Portrayals.

    Science.gov (United States)

    Knobloch-Westerwick, Silvia

    2015-01-01

    Much research has demonstrated negative impacts of idealized-body imagery exposure on body satisfaction. Yet, paradoxically, media with such imagery attract mass audiences. Few studies showed women's body satisfaction increased due to thin-ideal exposure. The kind of social comparison women engage in (self-evaluation vs. self-improvement) may explain these inconsistent findings and the paradoxical attraction to thin-ideal messages. Across 5 days, thin-ideal messages were presented to 51 women; self-evaluation and self-improvement social comparisons as well as body satisfaction were measured each day. A linear positive change in body satisfaction emerged. Greater self-improvement social comparisons increased this change, whereas greater self-evaluation social comparisons reduced it. Extent of both social comparison types changed during the prolonged exposure. A greater tendency to compare one's body with others' improved body satisfaction through self-improvement social comparisons and fostered weight-loss behaviors through self-evaluation social comparisons.

  16. A comparison of lower canine retraction and loss of anchorage between conventional and self-ligating brackets: a single-center randomized split-mouth controlled trial.

    Science.gov (United States)

    da Costa Monini, André; Júnior, Luiz Gonzaga Gandini; Vianna, Alexandre Protásio; Martins, Renato Parsekian

    2017-05-01

    To evaluate the rate of lower canine retraction, anchorage loss, and changes on lower canines and first molars axial inclination using self-ligating and conventional brackets. Twenty-five adult patients with a treatment plan involving extractions of four first premolars were selected for this split-mouth trial and had either conventional or self-ligating brackets bonded to lower canines in a block randomization. Retraction was accomplished using 100-g nickel titanium closed-coil springs, which were reactivated each 4 weeks. Oblique radiographs were taken before and after total canine retraction and the cephalograms were superimposed on stable structures of the mandible. Cephalometric points were digitized twice by a single-blinded operator for error control and the average of the points were used to determine the following variables: canine cusp horizontal changes, molar cusp horizontal changes, and angulation changes in canines and molars. Paired t tests were used to analyze the blinded data for group differences. All patients reached final phase without bracket debonds. No differences were found between the two groups for all variables tested. No serious harm was observed. Both brackets showed the same rate of canine retraction and loss of anteroposterior anchorage of the molars. No changes were found between brackets regarding the inclination of canines and first molars. Using self-ligating brackets to retract lower canines will not increase the velocity of tooth movement, does not increase anchorage, and does not decrease tipping.

  17. Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children.

    Science.gov (United States)

    Watkinson, Simon; Harrison, Jayne E; Furness, Susan; Worthington, Helen V

    2013-09-30

    Prominent lower front teeth (termed reverse bite; under bite; Class III malocclusion) may be due to a combination of the jaw or tooth positions or both. The upper jaw (maxilla) can be too far back or the lower jaw (mandible) too far forward, or both. Prominent lower front teeth can also occur if the upper front teeth (incisors) are tipped back or the lower front teeth are tipped forwards, or both. Various treatment approaches have been described to correct prominent lower front teeth in children and adolescents. To assess the effects of orthodontic treatment for prominent lower front teeth in children and adolescents. We searched the following databases: Cochrane Oral Health Group's Trials Register (to 7 January 2013), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2012, Issue 12), MEDLINE via OVID (1946 to 7 January 2013), and EMBASE via OVID (1980 to 7 January 2013). Randomised controlled trials (RCTs) recruiting children or adolescents or both (aged 16 years or less) receiving any type of orthodontic treatment to correct prominent lower front teeth (Class III malocclusion). Orthodontic treatments were compared with control groups who received either no treatment, delayed treatment or a different active intervention. Screening of references, identification of included and excluded studies, data extraction and assessment of the risk of bias of the included studies was performed independently and in duplicate by two review authors. The mean differences with 95% confidence intervals were calculated for continuous data. Meta-analysis was only undertaken when studies of similar comparisons reported comparable outcome measures. A fixed-effect model was used. The I2 statistic was used as a measure of statistical heterogeneity. Seven RCTs with a total of 339 participants were included in this review. One study was assessed as at low risk of bias, three studies were at high risk of bias, and in the remaining three studies risk of bias

  18. El ideal de Yo bajo la tutela del Superyó.

    Directory of Open Access Journals (Sweden)

    María Paulina Mejía.

    1999-01-01

    Full Text Available Este texto se ocupará de analizar la naturaleza y función del Ideal del Yo, así como s relación con la instancia del superyó. Para tal fin se retomará el texto Introducción al Narcisismo, en el cual Freud introduce el Superyó con el nombre de conciencia moral y en el que, a su vez, explica el origen del ideal del Yo como el heredero de la ley y el nacimiento de del “juicio propio”. El ideal del Yo y el Superyó, ambos herederos del Complejo de Edipo, tienen en común que, si bien son resultado de la intervención de la ley y se valen del lenguaje, no se acogen a su estructura y a sus leyes, es decir, que no funcionan con la lógica de la falta y privilegian significantes unarios, que por estar solos no posibilitan la construcción de sentido.En síntesis, este artículo pretende demostrar cómo el Ideal del Yo, bajo la tutela del Superyó, logra darle respuestas al sujeto en relación al ser hombre y ser mujer pero del lado del goce. La lógica que se contrapone a la dimensión del lenguaje y el deseo, los cuales se estructuran a partir de la falta. El ser desde esta dimensión deja de ser una certeza para constituirse en una pregunta

  19. Customization: Ideal Varieties, Product Uniqueness and Price Competition

    OpenAIRE

    Oksana Loginova; X. Henry Wang

    2009-01-01

    We study customization in the Hotelling model with two firms. In addition to providing ideal varieties, the perceived uniqueness of a customized product contributes independently to consumer utility. We show that only when consumer preferences for uniqueness are high customization occurs in equilibrium.

  20. Quantum statistics of ideal gases in confined space

    OpenAIRE

    Dai, Wu-Sheng; Xie, Mi

    2002-01-01

    In this paper, the effects of boundary and connectivity on ideal gases in two-dimensional confined space and three-dimensional tubes are discussed in detail based on the analytical result. The implication of such effects on the mesoscopic system is also revealed.

  1. Quantum statistics of ideal gases in confined space

    International Nuclear Information System (INIS)

    Dai Wusheng; Xie Mi

    2003-01-01

    In this Letter, the effects of boundary and connectivity on ideal gases in two-dimensional confined space and three-dimensional tubes are discussed in detail based on the analytical result. The implication of such effects on the mesoscopic system is also revealed

  2. Anharmonic Vibrations of an "Ideal" Hooke's Law Oscillator

    Science.gov (United States)

    Thomchick, John; McKelvey, J. P.

    1978-01-01

    Presents a model describing the vibrations of a mass connected to fixed supports by "ideal" Hooke's law springs which may serve as a starting point in the study of the properties of irons in a crystal undergoing soft mode activated transition. (SL)

  3. Assessment of blinding success among dental implant clinical trials: A systematic review

    Directory of Open Access Journals (Sweden)

    Jafar Kolahi

    2015-01-01

    Full Text Available Introduction: It is widely believed that blinding is a cornerstone of randomized clinical trials and that significant bias may result from unsuccessful blinding. However, it is not enough to claim that a clinical trial is single- or double-blinded and that assessment of the success of blinding is ideal. The aim of this study was to evaluate the prevalence of assessment of blinding success among dental implant clinical trials and to introduce methods of blinding assessment to the implant research community. Methods: In November 2014, PubMed was searched by blinded and experienced researchers with the query "implant AND (blindFNx01 OR maskFNx01" using the following filters: (1 Article type: clinical trial; (2 Journal categories: dental journals; (3 Field: title/abstract. Consequently, title/abstract was reviewed in all relevant articles to find any attempt to assess the success of blinding in dental implant clinical trials. Results: The PubMed search results yielded 86 clinical trials. The point of interest is that when "blindFNx01 OR maskFNx01" was deleted from the query, the number of results increased to 1688 clinical trials. This shows that only 5% of dental implant clinical trials tried to use blinding. Disappointingly, we could not find any dental implant clinical trial reporting any attempt to assess the success of blinding. Conclusion: The current status of turning a blind eye to unblinding in dental implant clinical trials is not tolerable and needs to be improved. Researchers, protocol reviewers, local ethical committees, journal reviewers, and editors should make a concerted effort to incorporate, report, and publish such information to understand its potential impact on study results.

  4. Mellem bureaukrati, klient og professionelle idealer

    DEFF Research Database (Denmark)

    Sandholm Larsen, Niels; Johnsen, Helle; Larsen, Kristian

    2015-01-01

    Between Bureaucracy, Clients and Professional Ideals – a Sociological Approach to Midwifes Experiences Monitoring Fetal Heartbeat Using Different Technologies. This article examines professionals’ perspectives on shifts in status of technologies. The article builds on data from focus group...... in a field of cross pressures from organizational efficiency demands, evidence based medicine, professional values and client interests. Furthermore, data analysis illustrates how professional priorities and accounts refer to structural conditions and transformation processes influenced by new technologies...

  5. Generalized uncertainty principle and the maximum mass of ideal white dwarfs

    Energy Technology Data Exchange (ETDEWEB)

    Rashidi, Reza, E-mail: reza.rashidi@srttu.edu

    2016-11-15

    The effects of a generalized uncertainty principle on the structure of an ideal white dwarf star is investigated. The equation describing the equilibrium configuration of the star is a generalized form of the Lane–Emden equation. It is proved that the star always has a finite size. It is then argued that the maximum mass of such an ideal white dwarf tends to infinity, as opposed to the conventional case where it has a finite value.

  6. Characterizations of intuitionistic fuzzy ideals and filters based on lattice operations

    Directory of Open Access Journals (Sweden)

    Soheyb Milles

    2017-11-01

    Full Text Available In a recent paper, Thomas and Nair have introduced the notions of intuitionistic fuzzy ideal and intuitionistic fuzzy filter on a lattice and some basic properties were proved. In this paper, we characterize these notions in terms of the lattice operations and in terms of their associated crisp sets. We introduce the notions of prime intuitionistic fuzzy ideal and filter as interesting kinds, and then we investigate their various characterizations and different properties.

  7. Single-stage laparoscopic common bile duct exploration and cholecystectomy versus two-stage endoscopic stone extraction followed by laparoscopic cholecystectomy for patients with gallbladder stones with common bile duct stones: systematic review and meta-analysis of randomized trials with trial sequential analysis.

    Science.gov (United States)

    Singh, Anand Narayan; Kilambi, Ragini

    2018-03-30

    The ideal management of common bile duct (CBD) stones associated with gall stones is a matter of debate. We planned a meta-analysis of randomized trials comparing single-stage laparoscopic CBD exploration and cholecystectomy (LCBDE) with two-stage preoperative endoscopic stone extraction followed by cholecystectomy (ERCP + LC). We searched the Pubmed/Medline, Web of science, Science citation index, Google scholar and Cochrane Central Register of Controlled trials electronic databases till June 2017 for all English language randomized trials comparing the two approaches. Statistical analysis was performed using Review Manager (RevMan) [Computer program], Version 5.3. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2014 and results were expressed as odds ratio for dichotomous variables and mean difference for continuous. p value ≤ 0.05 was considered significant. Trial sequential analysis (TSA) was performed using TSA version 0.9.5.5 (Copenhagen: The Copenhagen Trial Unit, Centre for Clinical Intervention Research, 2016). PROSPERO trial registration number is CRD42017074673. A total of 11 trials were included in the analysis, with a total of 1513 patients (751-LCBDE; 762-ERCP + LC). LCBDE was found to have significantly lower rates of technical failure [OR 0.59, 95% CI (0.38, 0.93), p = 0.02] and shorter hospital stay [MD - 1.63, 95% CI (- 3.23, - 0.03), p = 0.05]. There was no significant difference in mortality [OR 0.37, 95% CI (0.09, 1.51), p = 0.17], morbidity [OR 0.97, 95% CI (0.70, 1.33), p = 0.84], cost [MD - 379.13, 95% CI (- 784.80, 111.2), p = 0.13] or recurrent/retained stones [OR 1.01, 95% CI (0.38, 2.73), p = 0.98]. TSA showed that although the Z-curve crossed the boundaries of conventional significance, the estimated information size is yet to be achieved. Single-stage LCBDE is superior to ERCP + LC in terms of technical success and shorter hospital stay in good-risk patients with

  8. 75 FR 31511 - Ideal Federal Savings Bank, Baltimore, MD; Approval of Conversion Application

    Science.gov (United States)

    2010-06-03

    ... DEPARTMENT OF THE TREASURY Office of Thrift Supervision [AC-46: OTS No. 08283] Ideal Federal Savings Bank, Baltimore, MD; Approval of Conversion Application Notice is hereby given that on May 24, 2010, the Office of Thrift Supervision approved the application of Ideal Federal Savings Bank...

  9. Effects of entanglement in an ideal optical amplifier

    Science.gov (United States)

    Franson, J. D.; Brewster, R. A.

    2018-04-01

    In an ideal linear amplifier, the output signal is linearly related to the input signal with an additive noise that is independent of the input. The decoherence of a quantum-mechanical state as a result of optical amplification is usually assumed to be due to the addition of quantum noise. Here we show that entanglement between the input signal and the amplifying medium can produce an exponentially-large amount of decoherence in an ideal optical amplifier even when the gain is arbitrarily close to unity and the added noise is negligible. These effects occur for macroscopic superposition states, where even a small amount of gain can leave a significant amount of which-path information in the environment. Our results show that the usual input/output relation of a linear amplifier does not provide a complete description of the output state when post-selection is used.

  10. Numbers and meanings. Ideality in the incipient Husserl’s phenomenology

    Directory of Open Access Journals (Sweden)

    José Manuel Chillón

    2017-04-01

    Full Text Available The reflection on numbers and meanings are a good example of how the incipient phenomenology is in the realm of pure logic. The paper states that, due to ambiguities in these early works and in order to draw a reflection that does not tear the philosophical personality of Husserl, the thesis of the ideality be read from the perspective of later works. This paper reconstructs, from initial analysis of the numbers and meanings, the thesis of the ideality Husserl which, in our view, detect the fundamental aspects of phenomenology despite the subsequent abandonment of the eidetic realism.

  11. Condensation and critical exponents of an ideal non-Abelian gas

    Science.gov (United States)

    Talaei, Zahra; Mirza, Behrouz; Mohammadzadeh, Hosein

    2017-11-01

    We investigate an ideal gas obeying non-Abelian statistics and derive the expressions for some thermodynamic quantities. It is found that thermodynamic quantities are finite at the condensation point where their derivatives diverge and, near this point, they behave as \\vert T-Tc\\vert^{-ρ} in which Tc denotes the condensation temperature and ρ is a critical exponent. The critical exponents related to the heat capacity and compressibility are obtained by fitting numerical results and others are obtained using the scaling law hypothesis for a three-dimensional non-Abelian ideal gas. This set of critical exponents introduces a new universality class.

  12. Low molecular weight heparin for prevention of venous thromboembolism in patients with lower-leg immobilization.

    Science.gov (United States)

    Testroote, Mark; Stigter, Willem A H; Janssen, Loes; Janzing, Heinrich M J

    2014-04-25

    Immobilization of the lower leg is associated with venous thromboembolism (VTE). Low molecular weight heparin (LMWH) is an anticoagulant treatment which might be used in adult patients with lower-leg immobilization to prevent deep venous thrombosis (DVT) and its complications. This is an update of the review first published in 2008. To assess the effectiveness of low molecular weight heparin for the prevention of venous thromboembolism in patients with lower-leg immobilization in an ambulant setting. For this update the Cochrane Peripheral Vascular Diseases Group Trials Search Co-ordinator searched the Specialised Register (last searched June 2013) and CENTRAL (2013, Issue 5). Randomized controlled trials (RCTs) and controlled clinical trials (CCTs) that described thromboprophylaxis by means of LMWH compared with no prophylaxis or placebo in adult patients with lower-leg immobilization. Immobilization was by means of a plaster cast or brace. Two authors independently assessed trial quality and extracted data. The review authors contacted the trial authors for additional information if required. Statistical analysis was carried out using Review Manager (RevMan 5). We included six RCTs fulfilling the above criteria with a total of 1490 patients. We found an incidence of VTE ranging from 4.3% to 40% in patients who had a leg injury that had been immobilized in a plaster cast or a brace for at least one week and who received no prophylaxis, or placebo. This number was significantly lower in patients who received daily subcutaneous injections of LMWH during immobilization (event rates ranging from 0% to 37%; odds ratio (OR) 0.49; fixed 95% confidence interval (CI) 0.34 to 0.72; with minimal evidence of heterogeneity with an I(2) of 20%, P = 0. 29). Comparable results were seen in the following subcategories: operated patients, conservatively treated patients, patients with fractures, patients with soft-tissue injuries, patients with proximal thrombosis, patients with

  13. The Septic Shock 3.0 Definition and Trials: A Vasopressin and Septic Shock Trial Experience.

    Science.gov (United States)

    Russell, James A; Lee, Terry; Singer, Joel; Boyd, John H; Walley, Keith R

    2017-06-01

    The Septic Shock 3.0 definition could alter treatment comparisons in randomized controlled trials in septic shock. Our first hypothesis was that the vasopressin versus norepinephrine comparison and 28-day mortality of patients with Septic Shock 3.0 definition (lactate > 2 mmol/L) differ from vasopressin versus norepinephrine and mortality in Vasopressin and Septic Shock Trial. Our second hypothesis was that there are differences in plasma cytokine levels in Vasopressin and Septic Shock Trial for lactate less than or equal to 2 versus greater than 2 mmol/L. Retrospective analysis of randomized controlled trial. Multicenter ICUs. We compared vasopressin-to-norepinephrine group 28- and 90-day mortality in Vasopressin and Septic Shock Trial in lactate subgroups. We measured 39 cytokines to compare patients with lactate less than or equal to 2 versus greater than 2 mmol/L. Patients with septic shock with lactate greater than 2 mmol/L or less than or equal to 2 mmol/L, randomized to vasopressin or norepinephrine. Concealed vasopressin (0.03 U/min.) or norepinephrine infusions. The Septic Shock 3.0 definition would have decreased sample size by about half. The 28- and 90-day mortality rates were 10-12 % higher than the original Vasopressin and Septic Shock Trial mortality. There was a significantly (p = 0.028) lower mortality with vasopressin versus norepinephrine in lactate less than or equal to 2 mmol/L but no difference between treatment groups in lactate greater than 2 mmol/L. Nearly all cytokine levels were significantly higher in patients with lactate greater than 2 versus less than or equal to 2 mmol/L. The Septic Shock 3.0 definition decreased sample size by half and increased 28-day mortality rates by about 10%. Vasopressin lowered mortality versus norepinephrine if lactate was less than or equal to 2 mmol/L. Patients had higher plasma cytokines in lactate greater than 2 versus less than or equal to 2 mmol/L, a brisker cytokine response to infection. The Septic

  14. Holding fat stereotypes is associated with lower body dissatisfaction in normal weight Caucasian women who engage in body surveillance.

    Science.gov (United States)

    Kim, Jean; Jarry, Josée L

    2014-09-01

    This study examined the moderating effect of body surveillance on the relationship between fat stereotype endorsement and body dissatisfaction in normal weight women. Participants (N=225) completed online measures of fat stereotyping, body surveillance, body dissatisfaction, and internalized thin ideals. After accounting for thin ideals, body surveillance moderated the relationship between fat stereotypes and body dissatisfaction. Contrary to hypotheses, higher fat stereotype endorsement predicted lower body dissatisfaction in women with higher body surveillance. Conversely, higher fat stereotype endorsement predicted greater body dissatisfaction in women with lower body surveillance. Thus, endorsing fat stereotypes appears protective against body dissatisfaction in normal weight women who extensively engage in body surveillance. For women who hold fat stereotypes and report high body surveillance, we propose that downward appearance comparison may create a contrast between themselves and the people with overweight whom they denigrate, thus improving body dissatisfaction. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Genetic and environmental influences on thin-ideal internalization across puberty and preadolescent, adolescent, and young adult development.

    Science.gov (United States)

    Suisman, Jessica L; Thompson, J Kevin; Keel, Pamela K; Burt, S Alexandra; Neale, Michael; Boker, Steven; Sisk, Cheryl; Klump, Kelly L

    2014-11-01

    Mean-levels of thin-ideal internalization increase during adolescence and pubertal development, but it is unknown whether these phenotypic changes correspond to developmental changes in etiological (i.e., genetic and environmental) risk. Given the limited knowledge on risk for thin-ideal internalization, research is needed to guide the identification of specific types of risk factors during critical developmental periods. The present twin study examined genetic and environmental influences on thin-ideal internalization across adolescent and pubertal development. Participants were 1,064 female twins (ages 8-25 years) from the Michigan State University Twin Registry. Thin-ideal internalization and pubertal development were assessed using self-report questionnaires. Twin moderation models were used to examine if age and/or pubertal development moderate genetic and environmental influences on thin-ideal internalization. Phenotypic analyses indicated significant increases in thin-ideal internalization across age and pubertal development. Twin models suggested no significant differences in etiologic effects across development. Nonshared environmental influences were most important in the etiology of thin-ideal internalization, with genetic, shared environmental, and nonshared environmental accounting for approximately 8%, 15%, and 72%, respectively, of the total variance. Despite mean-level increases in thin-ideal internalization across development, the relative influence of genetic versus environmental risk did not differ significantly across age or pubertal groups. The majority of variance in thin-ideal internalization was accounted for by environmental factors, suggesting that mean-level increases in thin-ideal internalization may reflect increases in the magnitude/strength of environmental risk across this period. Replication is needed, particularly with longitudinal designs that assess thin-ideal internalization across key developmental phases. © 2014 Wiley

  16. The Masculinity of Mr. Right: Feminist Identity and Heterosexual Women's Ideal Romantic Partners

    Science.gov (United States)

    Backus, Faedra R.; Mahalik, James R.

    2011-01-01

    Our study explored the relationship between feminist identity and women's report of an ideal male partner's conformity to masculine gender role norms. Heterosexual, mostly White, college women (N = 183) completed measures assessing feminist beliefs and the masculinity characteristics of an ideal male partner. Results indicated that feminist…

  17. The influence of molecular complexity on expanding flows of ideal and dense gases

    NARCIS (Netherlands)

    Harinck, J.; Guardone, A.; Colonna, P.

    2009-01-01

    This paper presents an investigation about the effect of the complexity of a fluid molecule on the fluid dynamic quantities sound speed, velocity, and Mach number in isentropic expansions. Ideal-gas and dense-gas expansions are analyzed, using the polytropic ideal gas and Van der Waals thermodynamic

  18. In Vivo Assessment of Neurodegeneration in Type C Niemann-Pick Disease by IDEAL-IQ.

    Science.gov (United States)

    Guo, Ruo-Mi; Li, Qing-Ling; Luo, Zhong-Xing; Tang, Wen; Jiao, Ju; Wang, Jin; Kang, Zhuang; Chen, Shao-Qiong; Zhang, Yong

    2018-01-01

    To noninvasively assess the neurodegenerative changes in the brain of patients with Niemann-Pick type C (NPC) disease by measuring the lesion tissue with the iterative decomposition of water and fat with echo asymmetry and least square estimation-iron quantification (IDEAL-IQ). Routine brain MRI, IDEAL-IQ and 1 H-proton magnetic resonance spectroscopy ( 1 H-MRS, served as control) were performed on 12 patients with type C Niemann-Pick disease (4 males and 8 females; age range, 15-61 years; mean age, 36 years) and 20 healthy subjects (10 males and 10 females; age range, 20-65 years; mean age, 38 years). The regions with lesion and the normal appearing regions (NARs) of patients were measured and analyzed based on the fat/water signal intensity on IDEAL-IQ and the lipid peak on 1 H-MRS. Niemann-Pick type C patients showed a higher fat/water signal intensity ratio with IDEAL-IQ on T2 hyperintensity lesions and NARs (3.7-4.9%, p IQ instead of 1 H-MRS. The findings of this study suggested that IDEAL-IQ may be useful as a noninvasive and objective method in the evaluation of patients with NPC; additionally, IDEAL-IQ can be used to quantitatively measure the brain parenchymal adipose content and monitor patient follow-up after treatment of NPC.

  19. Fitting measurement models to vocational interest data: are dominance models ideal?

    Science.gov (United States)

    Tay, Louis; Drasgow, Fritz; Rounds, James; Williams, Bruce A

    2009-09-01

    In this study, the authors examined the item response process underlying 3 vocational interest inventories: the Occupational Preference Inventory (C.-P. Deng, P. I. Armstrong, & J. Rounds, 2007), the Interest Profiler (J. Rounds, T. Smith, L. Hubert, P. Lewis, & D. Rivkin, 1999; J. Rounds, C. M. Walker, et al., 1999), and the Interest Finder (J. E. Wall & H. E. Baker, 1997; J. E. Wall, L. L. Wise, & H. E. Baker, 1996). Item response theory (IRT) dominance models, such as the 2-parameter and 3-parameter logistic models, assume that item response functions (IRFs) are monotonically increasing as the latent trait increases. In contrast, IRT ideal point models, such as the generalized graded unfolding model, have IRFs that peak where the latent trait matches the item. Ideal point models are expected to fit better because vocational interest inventories ask about typical behavior, as opposed to requiring maximal performance. Results show that across all 3 interest inventories, the ideal point model provided better descriptions of the response process. The importance of specifying the correct item response model for precise measurement is discussed. In particular, scores computed by a dominance model were shown to be sometimes illogical: individuals endorsing mostly realistic or mostly social items were given similar scores, whereas scores based on an ideal point model were sensitive to which type of items respondents endorsed.

  20. A moral house divided: How idealized family models impact political cognition

    Science.gov (United States)

    Feinberg, Matthew; Wehling, Elisabeth

    2018-01-01

    People’s political attitudes tend to fall into two groups: progressive and conservative. Moral Politics Theory asserts that this ideological divide is the product of two contrasting moral worldviews, which are conceptually anchored in individuals’ cognitive models about ideal parenting and family life. These models, here labeled the strict and nurturant models, serve as conceptual templates for how society should function, and dictate whether one will endorse more conservative or progressive positions. According to Moral Politics Theory, individuals map their parenting ideals onto the societal domain by engaging the nation-as-family metaphor, which facilitates reasoning about the abstract social world (the nation) in terms of more concrete world experience (family life). In the present research, we conduct an empirical examination of these core assertions of Moral Politics Theory. In Studies 1–3, we experimentally test whether family ideals directly map onto political attitudes while ruling out alternative explanations. In Studies 4–5, we use both correlational and experimental methods to examine the nation-as-family metaphor’s role in facilitating the translation of family beliefs into societal beliefs and, ultimately, political attitudes. Overall, we found consistent support for Moral Politics Theory’s assertions that family ideals directly impact political judgment, and that the nation-as-family metaphor serves a mediating role in this phenomenon. PMID:29641618

  1. Accounting Employers' Expectations--The Ideal Accounting Graduates

    Science.gov (United States)

    Low, Mary; Botes, Vida; Rue, David Dela; Allen, Jackie

    2016-01-01

    This research examined what accounting employers are seeking in their "ideal" accounting graduate and sought to provide clarification on the "expectation gap" between what accounting employers require in their graduates, and the skills these graduates are exhibiting. Adopting a qualitative research method, this research paper…

  2. A decomposition of pairwise continuity via ideals

    Directory of Open Access Journals (Sweden)

    Mahes Wari

    2016-02-01

    Full Text Available In this paper, we introduce and study the notions of (i, j - regular - ℐ -closed sets, (i, j - Aℐ -sets, (i, j - ℐ -locally closed sets, p- Aℐ -continuous functions and p- ℐ -LC-continuous functions in ideal bitopological spaces and investigate some of their properties. Also, a new decomposition of pairwise continuity is obtained using these sets.

  3. A Riccati solution for the ideal MHD plasma response with applications to real-time stability control

    Science.gov (United States)

    Glasser, Alexander; Kolemen, Egemen; Glasser, A. H.

    2018-03-01

    Active feedback control of ideal MHD stability in a tokamak requires rapid plasma stability analysis. Toward this end, we reformulate the δW stability method with a Hamilton-Jacobi theory, elucidating analytical and numerical features of the generic tokamak ideal MHD stability problem. The plasma response matrix is demonstrated to be the solution of an ideal MHD matrix Riccati differential equation. Since Riccati equations are prevalent in the control theory literature, such a shift in perspective brings to bear a range of numerical methods that are well-suited to the robust, fast solution of control problems. We discuss the usefulness of Riccati techniques in solving the stiff ordinary differential equations often encountered in ideal MHD stability analyses—for example, in tokamak edge and stellarator physics. We demonstrate the applicability of such methods to an existing 2D ideal MHD stability code—DCON [A. H. Glasser, Phys. Plasmas 23, 072505 (2016)]—enabling its parallel operation in near real-time, with wall-clock time ≪1 s . Such speed may help enable active feedback ideal MHD stability control, especially in tokamak plasmas whose ideal MHD equilibria evolve with inductive timescale τ≳ 1s—as in ITER.

  4. Lower-extremity resistance training on unstable surfaces improves proxies of muscle strength, power and balance in healthy older adults: a randomised control trial.

    Science.gov (United States)

    Eckardt, Nils

    2016-11-24

    It is well documented that both balance and resistance training have the potential to mitigate intrinsic fall risk factors in older adults. However, knowledge about the effects of simultaneously executed balance and resistance training (i.e., resistance training conducted on unstable surfaces [URT]) on lower-extremity muscle strength, power and balance in older adults is insufficient. The objective of the present study was to compare the effects of machine-based stable resistance training (M-SRT) and two types of URT, i.e., machine-based (M-URT) and free-weight URT (F-URT), on measures of lower-extremity muscle strength, power and balance in older adults. Seventy-five healthy community-dwelling older adults aged 65-80 years, were assigned to three intervention groups: M-SRT, M-URT and F-URT. Over a period of ten weeks, all participants exercised two times per week with each session lasting ~60 min. Tests included assessment of leg muscle strength (e.g., maximal isometric leg extension strength), power (e.g., chair rise test) and balance (e.g., functional reach test), carried out before and after the training period. Furthermore, maximal training load of the squat-movement was assessed during the last training week. Maximal training load of the squat-movement was significantly lower in F-URT in comparison to M-SRT and M-URT. However, lower-extremity resistance training conducted on even and uneven surfaces meaningfully improved proxies of strength, power and balance in all groups. M-URT produced the greatest improvements in leg extension strength and F-URT in the chair rise test and functional reach test. Aside from two interaction effects, overall improvements in measures of lower-extremity muscle strength, power and balance were similar across training groups. Importantly, F-URT produced similar results with considerably lower training load as compared to M-SRT and M-URT. Concluding, F-URT seems an effective and safe alternative training program to mitigate

  5. Value-based HR practices, i-deals and clinical error control with CSR as a moderator.

    Science.gov (United States)

    Luu, Tuan; Rowley, Chris; Siengthai, Sununta; Thanh Thao, Vo

    2017-05-08

    Purpose Notwithstanding the rising magnitude of system factors in patient safety improvement, "human factors" such as idiosyncratic deals (i-deals) which also contribute to the adjustment of system deficiencies should not be neglected. The purpose of this paper is to investigate the role of value-based HR practices in catalyzing i-deals, which then influence clinical error control. The research further examines the moderating role of corporate social responsibility (CSR) on the effect of value-based HR practices on i-deals. Design/methodology/approach The data were collected from middle-level clinicians from hospitals in the Vietnam context. Findings The research results confirmed the effect chain from value-based HR practices through i-deals to clinical error control with CSR as a moderator. Originality/value The HRM literature is expanded through enlisting i-deals and clinical error control as the outcomes of HR practices.

  6. Evaluation of the cost effectiveness of vesico-amniotic shunting in the management of congenital lower urinary tract obstruction (based on data from the PLUTO Trial.

    Directory of Open Access Journals (Sweden)

    Lavanya Diwakar

    Full Text Available OBJECTIVE: To determine the cost-effectiveness of in-utero percutaneous Vesico Amniotic Shunt (VAS in the management of fetal lower urinary tract obstruction (LUTO. DESIGN: Model based economic analysis using data from the randomised controlled arm of the PLUTO (percutaneous vesico-amniotic shunting for lower urinary tract obstruction trial. SETTING: Fetal medicine departments in United Kingdom, Ireland and Netherlands. POPULATION OR SAMPLE: Pregnant women with a male, singleton fetus with LUTO. METHODS: Costs and outcomes were prospectively collected in the trial; three separate base case analyses were performed using the intention to treat (ITT, per protocol and uniform prior methods. Deterministic and probabilistic sensitivity analyses were performed to explore data uncertainty. MAIN OUTCOME MEASURES: Survival at 28 days, 1 year and disease free survival at 1 year. RESULTS: VAS was more expensive but appeared to result in higher rates of survival compared with conservative management in patients with LUTO. Using ITT analysis the incremental cost effectiveness ratios based on outcomes of survival at 28 days, 1 year, or 1 morbidity-free year on the VAS arm were £ 15,506, £ 15,545, and £ 43,932, respectively. CONCLUSIONS: VAS is a more expensive option compared to the conservative approach in the management of individuals with LUTO. Data from the RCT suggest that VAS improves neonatal survival but does not result in significant improvements in morbidity. Our analysis concludes that VAS is not likely to be cost effective in the management of these patients given the NICE (National Institute of Health and Clinical Excellence cost threshold of £ 20,000 per QALY.

  7. Coexistence of photonic and atomic Bose-Einstein condensates in ideal atomic gases

    Directory of Open Access Journals (Sweden)

    N. Boichenko

    2015-12-01

    Full Text Available We have studied conditions of photon Bose-Einstein condensate formation that is in thermodynamic equilibrium with ideal gas of two-level Bose atoms below the degeneracy temperature. Equations describing thermodynamic equilibrium in the system were formulated; critical temperatures and densities of photonic and atomic gas subsystems were obtained analytically. Coexistence conditions of these photonic and atomic Bose-Einstein condensates were found. There was predicted the possibility of an abrupt type of photon condensation in the presence of Bose condensate of ground-state atoms: it was shown that the slightest decrease of the temperature could cause a significant gathering of photons in the condensate. This case could be treated as a simple model of the situation known as "stopped light" in cold atomic gas. We also showed how population inversion of atomic levels can be created by lowering the temperature. The latter situation looks promising for light accumulation in atomic vapor at very low temperatures.

  8. Single fireball and fireball ideal gas

    International Nuclear Information System (INIS)

    Fiore, R.; Page, R.; Sertorio, L.

    1977-01-01

    In the paper the partition function of a macroscopic hadron system with two models is studied. In one model the mathematical fireball appears as a fundamental particle in a Boltzmann ideal gas occupying a volume V. In a second model the macroscopic volume V is divided in noninteracting boxes of volume Vsub(0), each one containing and interacting-pion gas. Both cases show the same limiting temperature Tsup(*) produced by the bootstrap equation, although far from Tsup(*) they represent different thermodynamic systems

  9. Ideal Magnetohydrodynamic Stability of the NCSX

    International Nuclear Information System (INIS)

    Fu, Guo Yong; Isaev, Maxim Yu; Ku, Long-Poe; Mikhailov, M.; Redi, M.H; Sanchez, Raul; Subbotin, A; Hirshman, Steven Paul; Cooper, W. Anthony; Monticello, D.; Reiman, A.H.; Zarnstorff, M.C.

    2007-01-01

    The ideal magnetohydrodynamic (MHD) stability of the National Compact Stellarator Experiment (NCSX) is extensively analyzed using the most advanced three-dimensional MHD codes. It is shown that the NCSX is stable to finite-n MHD modes, including the vertical mode, external kink modes and ballooning modes. However, high-n external kink modes that peak near the plasma edge are found to be weakly unstable. A global calculation shows that finite-n ballooning modes are significantly more stable than the local infinite-n modes

  10. Tipo físico ideal e satisfação com a imagem corporal de praticantes de caminhada Tipo físico ideal y satisfaccion con la imagen corporal de los praticantes de caminata Ideal physical type and body image satisfaction of regular walkers

    Directory of Open Access Journals (Sweden)

    Vinicius Oliveira Damasceno

    2005-06-01

    Full Text Available O objetivo do presente estudo foi quantificar o tipo físico ideal e verificar o nível de insatisfação com a imagem corporal de praticantes de caminhada. Participaram do estudo 186 pessoas: 87 mulheres (idade = 28,70 ± 12,6 anos, estatura = 161,6 ± 6,2cm, massa corporal = 58,9 ± 12,0kg e gordura = 25,7 ± 7,8 G% e 98 homens (idade = 27,9 ± 12,9 anos, estatura = 177,2 ± 6,9cm, massa corporal = 75,0 ± 12,3kg e gordura = 13,3 ± 6,1 G%. Solicitou-se que as pessoas indicassem qual silhueta correspondia ao seu corpo atualmente e qual gostariam de atingir. Apenas 24% das mulheres estão satisfeitas. A silhueta 3 foi apontada como ideal a ser atingido por 55% das mulheres (silhueta 2 = 18%; e 4 = 21%. A silhueta 3, de acordo com os resultados desse estudo, corresponde ao G% 20,5 ± 0,9% (EPM e ao IMC de 20,0 ± 0,3kg/m² (EPM. Quanto aos homens, apenas 18% estão satisfeitos. A silhueta 4 foi apontada como ideal por 47% dos homens (silhueta 3 = 23%; e 5 = 19%. A silhueta 4 corresponde ao G% 9,8 ± 1,4% (EPM e ao IMC de 23,1 ± 0,4kg/m² (EPM. Existe um tipo físico ideal para ambos os sexos. Não houve diferença entre o grau de insatisfação com a imagem corporal entre os sexos.El objetivo del presente estudio fué cuantificar el tipo físico ideal y verificar el nivel de insatisfacción con la imagen corporal de praticantes de caminata. Participaron del estudio 186 personas: 87 mujeres (edades = 28,70 ± 12,6 años, estatura = 161,6 ± 6,2 cm, masa corporal = 58,9 ± 12,0 kg y gordura = 25,7 ± 7,8 G% y 98 hombres (edades = 27.9 ± 12,9 años, estatura = 177,2 ± 6,9 cm, masa corporal = 75,0 ± 12,3 kg y gordura = 13,3 ± 6,1 G%. Se solicitó que las personas indicasen cual era la silueta que correspondía a su cuerpo actualmente e cual guastarian de tener. Apenas 24% de las mujeres están satisfechas. La silueta 3 fué designada como ideal a ser presentada por el 55 % de las mujeres (silueta 2 = 18%; y 4 = 21%. La silueta 3, de acuerdo con

  11. Continuous dose-response relationship of the LDL-cholesterol-lowering effect of phytosterol intake.

    Science.gov (United States)

    Demonty, Isabelle; Ras, Rouyanne T; van der Knaap, Henk C M; Duchateau, Guus S M J E; Meijer, Linsie; Zock, Peter L; Geleijnse, Johanna M; Trautwein, Elke A

    2009-02-01

    Phytosterols (plant sterols and stanols) are well known for their LDL-cholesterol (LDL-C)-lowering effect. A meta-analysis of randomized controlled trials in adults was performed to establish a continuous dose-response relationship that would allow predicting the LDL-C-lowering efficacy of different phytosterol doses. Eighty-four trials including 141 trial arms were included. A nonlinear equation comprising 2 parameters (the maximal LDL-C lowering and an incremental dose step) was used to describe the dose-response curve. The overall pooled absolute (mmol/L) and relative (%) LDL-C-lowering effects of phytosterols were also assessed with a random effects model. The pooled LDL-C reduction was 0.34 mmol/L (95% CI: -0.36, -0.31) or 8.8% (95% CI: -9.4, -8.3) for a mean daily dose of 2.15 g phytosterols. The impacts of subject baseline characteristics, food formats, type of phytosterols, and study quality on the continuous dose-response curve were determined by regression or subgroup analyses. Higher baseline LDL-C concentrations resulted in greater absolute LDL-C reductions. No significant differences were found between dose-response curves established for plant sterols vs. stanols, fat-based vs. non fat-based food formats and dairy vs. nondairy foods. A larger effect was observed with solid foods than with liquid foods only at high phytosterol doses (>2 g/d). There was a strong tendency (P = 0.054) towards a slightly lower efficacy of single vs. multiple daily intakes of phytosterols. In conclusion, the dose-dependent LDL-C-lowering efficacy of phytosterols incorporated in various food formats was confirmed and equations of the continuous relationship were established to predict the effect of a given phytosterol dose. Further investigations are warranted to investigate the impact of solid vs. liquid food formats and frequency of intake on phytosterol efficacy.

  12. Expanding the Evidence Base: Comparing Randomized Controlled Trials and Observational Studies of Statins.

    Science.gov (United States)

    Atar, Dan; Ong, Seleen; Lansberg, Peter J

    2015-01-01

    It is widely accepted that randomized controlled trials (RCTs) are the gold standard for demonstrating the efficacy of a given therapy (results under ideal conditions). Observational studies, on the other hand, can complement this by demonstrating effectiveness (results under real-world conditions). To examine the role that observational studies can play in complementing data from RCTs, we reviewed published studies for statins, a class of drugs that have been widely used to reduce the risk of cardiovascular (CV) events by lowering low-density lipoprotein cholesterol levels. RCTs have consistently demonstrated the benefits of statin treatment in terms of CV risk reduction and have demonstrated that more intensive statin therapy has incremental benefits over less intensive treatment. Observational studies of statin use in 'real-world' populations have served to augment the evidence base generated from statin RCTs in preselected populations of patients who are often at high CV risk and have led to similar safety and efficacy findings. They have also raised questions about factors affecting medication adherence, under-treatment, switching between statins, and failure to reach low-density lipoprotein cholesterol target levels, questions for which the answers could lead to improved patient care.

  13. Lower urinary tract symptoms after subtotal versus total abdominal hysterectomy: exploratory analyses from a randomized clinical trial with a 14-year follow-up.

    Science.gov (United States)

    Andersen, Lea Laird; Møller, Lars Mikael Alling; Gimbel, Helga

    2015-12-01

    Lower urinary tract symptoms (LUTS) are common after hysterectomy and increase after menopause. We aimed to compare subtotal with total abdominal hysterectomy regarding LUTS, including urinary incontinence (UI) subtypes, 14 years after hysterectomy. Main results from this randomized clinical trial have been published previously; the analyses covered in this paper are exploratory. We performed a long-term questionnaire follow-up of women in a randomized clinical trial (n = 319), from 1996 to 2000 comparing subtotal with total abdominal hysterectomy. Of the randomized women, ten had died and five had left Denmark; 304 women were contacted. For univariate analyses, a χ(2)-test was used, and for multivariate analyses, we used logistic regression. The questionnaire was answered by 197 (64.7 %) women (subtotal 97; total 100). More women had subjective stress UI (SUI) in the subtotal group (n = 60; 62.5 %) compared with the total group (n = 45; 45 %), with a relative risk (RR) of 1.39 [95 % confidence interval (CI) 1.06-1.81; P = 0.014]. No difference was seen between subtotal and total abdominal hysterectomy in other LUTS. Factors associated with UI were UI prior to hysterectomy, local estrogen treatment, and body mass index (BMI) > 25 kg/m(2). High BMI was primarily associated with mixed UI (MUI) and urgency symptoms. Predictors of bothersome LUTS were UI and incomplete bladder emptying. The difference in the frequency of subjectively assessed UI between subtotal and total abdominal hysterectomy (published previously) is caused by a difference in subjectively assessed SUI; UI prior to hysterectomy and high BMI are related to UI 14 years after hysterectomy. The trial is registered on clinicaltrials.gov under Nykoebing Falster County Hospital Record sj-268: Total versus subtotal hysterectomy: http://clinicaltrials.gov/ct2/show/NCT01880710?term=hysterectomy&rank=27.

  14. Work-Life Balance and Ideal Worker Expectations for Administrators

    Science.gov (United States)

    Wilk, Kelly E.

    2016-01-01

    This chapter explores the work-life experiences of administrators as well as whether and how the ideal worker model affects those experiences. Departmental and supervisory differences and technology complicate administrators' work-life experiences.

  15. Reconstructing the ideal results of a perturbed analog quantum simulator

    Science.gov (United States)

    Schwenk, Iris; Reiner, Jan-Michael; Zanker, Sebastian; Tian, Lin; Leppäkangas, Juha; Marthaler, Michael

    2018-04-01

    Well-controlled quantum systems can potentially be used as quantum simulators. However, a quantum simulator is inevitably perturbed by coupling to additional degrees of freedom. This constitutes a major roadblock to useful quantum simulations. So far there are only limited means to understand the effect of perturbation on the results of quantum simulation. Here we present a method which, in certain circumstances, allows for the reconstruction of the ideal result from measurements on a perturbed quantum simulator. We consider extracting the value of the correlator 〈Ôi(t ) Ôj(0 ) 〉 from the simulated system, where Ôi are the operators which couple the system to its environment. The ideal correlator can be straightforwardly reconstructed by using statistical knowledge of the environment, if any n -time correlator of operators Ôi of the ideal system can be written as products of two-time correlators. We give an approach to verify the validity of this assumption experimentally by additional measurements on the perturbed quantum simulator. The proposed method can allow for reliable quantum simulations with systems subjected to environmental noise without adding an overhead to the quantum system.

  16. Guidance for Researchers Developing and Conducting Clinical Trials in Practice-based Research Networks (PBRNs)

    Science.gov (United States)

    Dolor, Rowena J.; Schmit, Kristine M.; Graham, Deborah G.; Fox, Chester H.; Baldwin, Laura Mae

    2015-01-01

    Background There is increased interest nationally in multicenter clinical trials to answer questions about clinical effectiveness, comparative effectiveness, and safety in real-world community settings. Primary care practice-based research networks (PBRNs), comprising community- and/or academically affiliated practices committed to improving medical care for a range of health problems, offer ideal settings for these trials, especially pragmatic clinical trials. However, many researchers are not familiar with working with PBRNs. Methods Experts in practice-based research identified solutions to challenges that researchers and PBRN personnel experience when collaborating on clinical trials in PBRNs. These were organized as frequently asked questions in a draft document presented at a 2013 Agency for Health care Research and Quality PBRN conference workshop, revised based on participant feedback, then shared with additional experts from the DARTNet Institute, Clinical Translational Science Award PBRN, and North American Primary Care Research Group PBRN workgroups for further input and modification. Results The “Toolkit for Developing and Conducting Multi-site Clinical Trials in Practice-Based Research Networks” offers guidance in the areas of recruiting and engaging practices, budgeting, project management, and communication, as well as templates and examples of tools important in developing and conducting clinical trials. Conclusion Ensuring the successful development and conduct of clinical trials in PBRNs requires a highly collaborative approach between academic research and PBRN teams. PMID:25381071

  17. Existence of three-dimensional ideal-magnetohydrodynamic equilibria with current sheets

    Energy Technology Data Exchange (ETDEWEB)

    Loizu, J. [Max-Planck-Institut für Plasmaphysik, D-17491 Greifswald (Germany); Princeton Plasma Physics Laboratory, PO Box 451, Princeton, New Jersey 08543 (United States); Hudson, S. R.; Bhattacharjee, A.; Lazerson, S. [Princeton Plasma Physics Laboratory, PO Box 451, Princeton, New Jersey 08543 (United States); Helander, P. [Max-Planck-Institut für Plasmaphysik, D-17491 Greifswald (Germany)

    2015-09-15

    We consider the linear and nonlinear ideal plasma response to a boundary perturbation in a screw pinch. We demonstrate that three-dimensional, ideal-MHD equilibria with continuously nested flux-surfaces and with discontinuous rotational-transform across the resonant rational-surfaces are well defined and can be computed both perturbatively and using fully nonlinear equilibrium calculations. This rescues the possibility of constructing MHD equilibria with current sheets and continuous, smooth pressure profiles. The results predict that, even if the plasma acts as a perfectly conducting fluid, a resonant magnetic perturbation can penetrate all the way into the center of a tokamak without being shielded at the resonant surface.

  18. Relaxation in binary mixtures: Non-ideality, heterogeneity and re ...

    Indian Academy of Sciences (India)

    Unknown

    molecular dynamics simulations to evaluate the non-ideality in the ..... make sure that the clustering or phase separation (especially among similar species) ... dynamics simulation analysis of composition fluctuation in model I, which has been.

  19. Composition dependent non-ideality in aqueous binary mixtures as ...

    Indian Academy of Sciences (India)

    SBBM) where two constituents dislike each other, yet remain macroscopically homogeneous at intermediate to high temperatures. Interestingly, we find that the origin of strong composition dependent non-ideal behaviour lies in its phase ...

  20. Sensor-augmented pump therapy lowers HbA(1c) in suboptimally controlled Type 1 diabetes; a randomized controlled trial

    NARCIS (Netherlands)

    Hermanides, J.; Nørgaard, K.; Bruttomesso, D.; Mathieu, C.; Frid, A.; Dayan, C. M.; Diem, P.; Fermon, C.; Wentholt, I. M. E.; Hoekstra, J. B. L.; DeVries, J. H.

    2011-01-01

    To investigate the efficacy of sensor-augmented pump therapy vs. multiple daily injection therapy in patients with suboptimally controlled Type 1 diabetes. In this investigator-initiated multi-centre trial (the Eurythmics Trial) in eight outpatient centres in Europe, we randomized 83 patients with